LOCUS       DAEHWO010000001       142277 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEHWO010000001 DAEHWO010000000
VERSION     DAEHWO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 142277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 142277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..142277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.001"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            187..327
                     /locus_tag="KNP54_000001"
     CDS             187..327
                     /locus_tag="KNP54_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0890938.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(502..822)
                     /locus_tag="KNP54_000002"
     CDS             complement(502..822)
                     /locus_tag="KNP54_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBF0890939.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(942..1679)
                     /locus_tag="KNP54_000003"
     CDS             complement(942..1679)
                     /locus_tag="KNP54_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBF0890940.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1894..3717
                     /gene="acd"
                     /locus_tag="KNP54_000004"
     CDS             1894..3717
                     /gene="acd"
                     /locus_tag="KNP54_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBF0890941.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISEGNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3932..8230
                     /locus_tag="KNP54_000005"
     CDS             3932..8230
                     /locus_tag="KNP54_000005"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBF0890942.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8434..8895
                     /locus_tag="KNP54_000006"
     CDS             8434..8895
                     /locus_tag="KNP54_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBF0890943.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8925..10079
                     /gene="nusA"
                     /locus_tag="KNP54_000007"
     CDS             8925..10079
                     /gene="nusA"
                     /locus_tag="KNP54_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBF0890944.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10086..10367
                     /locus_tag="KNP54_000008"
     CDS             10086..10367
                     /locus_tag="KNP54_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBF0890945.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10357..10668
                     /locus_tag="KNP54_000009"
     CDS             10357..10668
                     /locus_tag="KNP54_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBF0890946.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10690..12630
                     /gene="infB"
                     /locus_tag="KNP54_000010"
     CDS             10690..12630
                     /gene="infB"
                     /locus_tag="KNP54_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBF0890947.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12673..13053
                     /gene="rbfA"
                     /locus_tag="KNP54_000011"
     CDS             12673..13053
                     /gene="rbfA"
                     /locus_tag="KNP54_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBF0890948.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            13034..14017
                     /locus_tag="KNP54_000012"
     CDS             13034..14017
                     /locus_tag="KNP54_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBF0890949.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEDVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            14030..14935
                     /gene="truB"
                     /locus_tag="KNP54_000013"
     CDS             14030..14935
                     /gene="truB"
                     /locus_tag="KNP54_000013"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBF0890950.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            15066..15995
                     /locus_tag="KNP54_000014"
     CDS             15066..15995
                     /locus_tag="KNP54_000014"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBF0890951.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            16099..16356
                     /gene="rpsO"
                     /locus_tag="KNP54_000015"
     CDS             16099..16356
                     /gene="rpsO"
                     /locus_tag="KNP54_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBF0890952.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            16596..17441
                     /locus_tag="KNP54_000016"
     CDS             16596..17441
                     /locus_tag="KNP54_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBF0890953.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            17566..19677
                     /gene="pnp"
                     /locus_tag="KNP54_000017"
     CDS             17566..19677
                     /gene="pnp"
                     /locus_tag="KNP54_000017"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBF0890954.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            19943..20686
                     /locus_tag="KNP54_000018"
     CDS             19943..20686
                     /locus_tag="KNP54_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBF0890955.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKAGKLSDVFK"
     gene            20844..22091
                     /locus_tag="KNP54_000019"
     CDS             20844..22091
                     /locus_tag="KNP54_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBF0890956.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINSVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            22126..22371
                     /locus_tag="KNP54_000020"
     CDS             22126..22371
                     /locus_tag="KNP54_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBF0890957.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            22381..23604
                     /gene="dapG"
                     /locus_tag="KNP54_000021"
     CDS             22381..23604
                     /gene="dapG"
                     /locus_tag="KNP54_000021"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBF0890958.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            23717..24451
                     /locus_tag="KNP54_000022"
     CDS             23717..24451
                     /locus_tag="KNP54_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBF0890959.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            24574..26985
                     /locus_tag="KNP54_000023"
     CDS             24574..26985
                     /locus_tag="KNP54_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBF0890960.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            26988..28046
                     /gene="mnmH"
                     /locus_tag="KNP54_000024"
     CDS             26988..28046
                     /gene="mnmH"
                     /locus_tag="KNP54_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBF0890961.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNDVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            28040..29374
                     /gene="rimO"
                     /locus_tag="KNP54_000025"
     CDS             28040..29374
                     /gene="rimO"
                     /locus_tag="KNP54_000025"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBF0890962.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHKIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            29361..29903
                     /gene="pgsA"
                     /locus_tag="KNP54_000026"
     CDS             29361..29903
                     /gene="pgsA"
                     /locus_tag="KNP54_000026"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBF0890963.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            30191..31237
                     /gene="recA"
                     /locus_tag="KNP54_000027"
     CDS             30191..31237
                     /gene="recA"
                     /locus_tag="KNP54_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBF0890964.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            31413..32954
                     /gene="rny"
                     /locus_tag="KNP54_000028"
     CDS             31413..32954
                     /gene="rny"
                     /locus_tag="KNP54_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBF0890965.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            33268..35604
                     /locus_tag="KNP54_000029"
     CDS             33268..35604
                     /locus_tag="KNP54_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBF0890966.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYSYDSVFLVSTKTNNYYHFNGLDRNLSANNSENQWYYTFLKNDDEYSLNVDNDEA
                     SNNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYNDKFDVVARLIDDKGFVQ
                     LAVDKTGHENINFFENSSSDLSNSKQLILNNKKEQKSFWYSSEKSKSYIVCQYIPSLK
                     WHLVLENDFTLMIKQLHLQFFKGIAVIVLIIIFVLFTITHVLKKYKNQIIKLSVSQKL
                     EYQKLLSKSTEGLYENIFEIDITNNKAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKRYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDEEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDNFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     NNNYVLIDKLERFCSKINQKKFVEQAEFSIACSIGVAMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHIFSEDSIDSISFHIDSRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSIGFDIFSPVLQDDLQMVLDTLREAISKRETFEIVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISSINTLLENK"
     gene            35986..37767
                     /locus_tag="KNP54_000030"
     CDS             35986..37767
                     /locus_tag="KNP54_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBF0890967.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(37849..38379)
                     /gene="lepB"
                     /locus_tag="KNP54_000031"
     CDS             complement(37849..38379)
                     /gene="lepB"
                     /locus_tag="KNP54_000031"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBF0890968.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(38419..39243)
                     /locus_tag="KNP54_000032"
     CDS             complement(38419..39243)
                     /locus_tag="KNP54_000032"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBF0890969.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            39500..40408
                     /locus_tag="KNP54_000033"
     CDS             39500..40408
                     /locus_tag="KNP54_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0890970.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            40552..41997
                     /locus_tag="KNP54_000034"
     CDS             40552..41997
                     /locus_tag="KNP54_000034"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBF0890971.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            42308..42760
                     /locus_tag="KNP54_000035"
     CDS             42308..42760
                     /locus_tag="KNP54_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0890972.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(43095..44291)
                     /locus_tag="KNP54_000036"
     CDS             complement(43095..44291)
                     /locus_tag="KNP54_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBF0890973.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            44676..45626
                     /gene="galT"
                     /locus_tag="KNP54_000037"
     CDS             44676..45626
                     /gene="galT"
                     /locus_tag="KNP54_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBF0890974.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            45787..46539
                     /gene="xth"
                     /locus_tag="KNP54_000038"
     CDS             45787..46539
                     /gene="xth"
                     /locus_tag="KNP54_000038"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBF0890975.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(46631..47407)
                     /locus_tag="KNP54_000039"
     CDS             complement(46631..47407)
                     /locus_tag="KNP54_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBF0890976.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKSSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMWKTNQFTLENVKQRKNK"
     gene            47722..49620
                     /locus_tag="KNP54_000040"
     CDS             47722..49620
                     /locus_tag="KNP54_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBF0890977.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            complement(49748..50869)
                     /locus_tag="KNP54_000041"
     CDS             complement(49748..50869)
                     /locus_tag="KNP54_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBF0890978.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            51068..51400
                     /locus_tag="KNP54_000042"
     CDS             51068..51400
                     /locus_tag="KNP54_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBF0890979.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            51387..52445
                     /locus_tag="KNP54_000043"
     CDS             51387..52445
                     /locus_tag="KNP54_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBF0890980.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINENSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            52438..53508
                     /locus_tag="KNP54_000044"
     CDS             52438..53508
                     /locus_tag="KNP54_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBF0890981.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDIAVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENGDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHNEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            53610..54146
                     /locus_tag="KNP54_000045"
     CDS             53610..54146
                     /locus_tag="KNP54_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBF0890982.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            54262..54969
                     /locus_tag="KNP54_000046"
     CDS             54262..54969
                     /locus_tag="KNP54_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBF0890983.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGQ"
     gene            54971..55687
                     /locus_tag="KNP54_000047"
     CDS             54971..55687
                     /locus_tag="KNP54_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBF0890984.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIASILIILLFMWQIPLCMFLASKFGMFVTVLTNMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            55689..56447
                     /locus_tag="KNP54_000048"
     CDS             55689..56447
                     /locus_tag="KNP54_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBF0890985.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            56582..57970
                     /locus_tag="KNP54_000049"
     CDS             56582..57970
                     /locus_tag="KNP54_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBF0890986.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(58046..58867)
                     /locus_tag="KNP54_000050"
     CDS             complement(58046..58867)
                     /locus_tag="KNP54_000050"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBF0890987.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYNRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            59103..60272
                     /locus_tag="KNP54_000051"
     CDS             59103..60272
                     /locus_tag="KNP54_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBF0890988.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            60455..60655
                     /locus_tag="KNP54_000052"
     CDS             60455..60655
                     /locus_tag="KNP54_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBF0890989.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            61076..61504
                     /locus_tag="KNP54_000053"
     CDS             61076..61504
                     /locus_tag="KNP54_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBF0890990.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(61647..62402)
                     /locus_tag="KNP54_000054"
     CDS             complement(61647..62402)
                     /locus_tag="KNP54_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBF0890991.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(63103..63609)
                     /locus_tag="KNP54_000055"
     CDS             complement(63103..63609)
                     /locus_tag="KNP54_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0890992.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            complement(63691..64011)
                     /locus_tag="KNP54_000056"
     CDS             complement(63691..64011)
                     /locus_tag="KNP54_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBF0890993.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            64180..64377
                     /locus_tag="KNP54_000057"
     CDS             64180..64377
                     /locus_tag="KNP54_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0890994.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            64482..64922
                     /locus_tag="KNP54_000058"
     CDS             64482..64922
                     /locus_tag="KNP54_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0890995.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            65171..65614
                     /locus_tag="KNP54_000059"
     CDS             65171..65614
                     /locus_tag="KNP54_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0890996.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            65619..66683
                     /locus_tag="KNP54_000060"
     CDS             65619..66683
                     /locus_tag="KNP54_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBF0890997.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            66697..67125
                     /locus_tag="KNP54_000061"
     CDS             66697..67125
                     /locus_tag="KNP54_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBF0890998.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYIGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            67251..67697
                     /locus_tag="KNP54_000062"
     CDS             67251..67697
                     /locus_tag="KNP54_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBF0890999.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            67724..67891
                     /locus_tag="KNP54_000063"
     CDS             67724..67891
                     /locus_tag="KNP54_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891000.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            67891..70344
                     /locus_tag="KNP54_000064"
     CDS             67891..70344
                     /locus_tag="KNP54_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891001.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MILAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     VWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            70344..70766
                     /locus_tag="KNP54_000065"
     CDS             70344..70766
                     /locus_tag="KNP54_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891002.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            71048..72577
                     /locus_tag="KNP54_000066"
     CDS             71048..72577
                     /locus_tag="KNP54_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBF0891003.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLNVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            72593..72919
                     /locus_tag="KNP54_000067"
     CDS             72593..72919
                     /locus_tag="KNP54_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBF0891004.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            72919..73347
                     /locus_tag="KNP54_000068"
     CDS             72919..73347
                     /locus_tag="KNP54_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBF0891005.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            73340..74392
                     /locus_tag="KNP54_000069"
     CDS             73340..74392
                     /locus_tag="KNP54_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBF0891006.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEINISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            74389..75087
                     /locus_tag="KNP54_000070"
     CDS             74389..75087
                     /locus_tag="KNP54_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBF0891007.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            75088..76071
                     /locus_tag="KNP54_000071"
     CDS             75088..76071
                     /locus_tag="KNP54_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBF0891008.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKVD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            76088..81409
                     /locus_tag="KNP54_000072"
     CDS             76088..81409
                     /locus_tag="KNP54_000072"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891009.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFIKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGNGNTMLIDNKGILKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDIFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNKSASQYT
                     EIGVSNVTDAYSSYNATFIVADEKKVYATGINTNYLLGVNPNDGVNINLTLINNWFYV
                     NPSGASYSTNSCTNDITKINNIIIYEYMAILCTNYGSFLTGYHGTLWTKPSDSTYRVQ
                     QQGITHAGYISNYIYNYYPTRCTQSSYSTNFAYLYYGESTSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHVFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNVFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYICNDVSIIVKNDNTCYVCGFVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNVIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAESNEPQA"
     gene            81426..81779
                     /locus_tag="KNP54_000073"
     CDS             81426..81779
                     /locus_tag="KNP54_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891010.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISSFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            82042..82302
                     /locus_tag="KNP54_000074"
     CDS             82042..82302
                     /locus_tag="KNP54_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891011.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTGIKGMLQNGV"
     gene            complement(82523..82978)
                     /locus_tag="KNP54_000075"
     CDS             complement(82523..82978)
                     /locus_tag="KNP54_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891012.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(83206..83625)
                     /locus_tag="KNP54_000076"
     CDS             complement(83206..83625)
                     /locus_tag="KNP54_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891013.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            83924..84133
                     /locus_tag="KNP54_000077"
     CDS             83924..84133
                     /locus_tag="KNP54_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891014.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            84165..84374
                     /locus_tag="KNP54_000078"
     CDS             84165..84374
                     /locus_tag="KNP54_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891015.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(84591..84989)
                     /locus_tag="KNP54_000079"
     CDS             complement(84591..84989)
                     /locus_tag="KNP54_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0891016.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(85410..87902)
                     /locus_tag="KNP54_000080"
     CDS             complement(85410..87902)
                     /locus_tag="KNP54_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0891017.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRTMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            complement(87916..88458)
                     /locus_tag="KNP54_000081"
     CDS             complement(87916..88458)
                     /locus_tag="KNP54_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0891018.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            88702..90216
                     /gene="glpK"
                     /locus_tag="KNP54_000082"
     CDS             88702..90216
                     /gene="glpK"
                     /locus_tag="KNP54_000082"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBF0891019.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(90330..90959)
                     /locus_tag="KNP54_000083"
     CDS             complement(90330..90959)
                     /locus_tag="KNP54_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0891020.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            91547..92338
                     /locus_tag="KNP54_000084"
     CDS             91547..92338
                     /locus_tag="KNP54_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBF0891021.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            92367..93587
                     /locus_tag="KNP54_000085"
     CDS             92367..93587
                     /locus_tag="KNP54_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBF0891022.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            93607..94302
                     /gene="pxpB"
                     /locus_tag="KNP54_000086"
     CDS             93607..94302
                     /gene="pxpB"
                     /locus_tag="KNP54_000086"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBF0891023.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            94332..95318
                     /locus_tag="KNP54_000087"
     CDS             94332..95318
                     /locus_tag="KNP54_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBF0891024.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGTRAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISEGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(95532..96098)
                     /locus_tag="KNP54_000088"
     CDS             complement(95532..96098)
                     /locus_tag="KNP54_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891025.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            96450..97517
                     /locus_tag="KNP54_000089"
     CDS             96450..97517
                     /locus_tag="KNP54_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBF0891026.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            97536..98696
                     /locus_tag="KNP54_000090"
     CDS             97536..98696
                     /locus_tag="KNP54_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBF0891027.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVATILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            98709..100805
                     /locus_tag="KNP54_000091"
     CDS             98709..100805
                     /locus_tag="KNP54_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBF0891028.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNGLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(100964..101308)
                     /locus_tag="KNP54_000092"
     CDS             complement(100964..101308)
                     /locus_tag="KNP54_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBF0891029.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            101600..102490
                     /locus_tag="KNP54_000093"
     CDS             101600..102490
                     /locus_tag="KNP54_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBF0891030.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEIIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            102708..103994
                     /locus_tag="KNP54_000094"
     CDS             102708..103994
                     /locus_tag="KNP54_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBF0891031.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(104083..104526)
                     /locus_tag="KNP54_000095"
     CDS             complement(104083..104526)
                     /locus_tag="KNP54_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBF0891032.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(104550..105344)
                     /locus_tag="KNP54_000096"
     CDS             complement(104550..105344)
                     /locus_tag="KNP54_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBF0891033.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(105909..106385)
                     /locus_tag="KNP54_000097"
     CDS             complement(105909..106385)
                     /locus_tag="KNP54_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBF0891034.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSIPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(106486..107655)
                     /locus_tag="KNP54_000098"
     CDS             complement(106486..107655)
                     /locus_tag="KNP54_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0891035.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNSNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            107818..108681
                     /locus_tag="KNP54_000099"
     CDS             107818..108681
                     /locus_tag="KNP54_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBF0891036.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            108752..109345
                     /locus_tag="KNP54_000100"
     CDS             108752..109345
                     /locus_tag="KNP54_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBF0891037.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(109596..110231)
                     /locus_tag="KNP54_000101"
     CDS             complement(109596..110231)
                     /locus_tag="KNP54_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBF0891038.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(110311..111042)
                     /locus_tag="KNP54_000102"
     CDS             complement(110311..111042)
                     /locus_tag="KNP54_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBF0891039.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LTLNIELKTDKINYPNIEKGVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            111373..113562
                     /locus_tag="KNP54_000103"
     CDS             111373..113562
                     /locus_tag="KNP54_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBF0891040.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKFGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDIYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            113974..115902
                     /locus_tag="KNP54_000104"
     CDS             113974..115902
                     /locus_tag="KNP54_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBF0891041.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            115889..116236
                     /locus_tag="KNP54_000105"
     CDS             115889..116236
                     /locus_tag="KNP54_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBF0891042.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(116478..118397)
                     /locus_tag="KNP54_000106"
     CDS             complement(116478..118397)
                     /locus_tag="KNP54_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBF0891043.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGFIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTPKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(118423..119229)
                     /locus_tag="KNP54_000107"
     CDS             complement(118423..119229)
                     /locus_tag="KNP54_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBF0891044.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            complement(119288..120736)
                     /gene="ddlR"
                     /locus_tag="KNP54_000108"
     CDS             complement(119288..120736)
                     /gene="ddlR"
                     /locus_tag="KNP54_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBF0891045.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            complement(120760..121659)
                     /locus_tag="KNP54_000109"
     CDS             complement(120760..121659)
                     /locus_tag="KNP54_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBF0891046.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            121917..123173
                     /locus_tag="KNP54_000110"
     CDS             121917..123173
                     /locus_tag="KNP54_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBF0891047.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGIAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            123231..124010
                     /locus_tag="KNP54_000111"
     CDS             123231..124010
                     /locus_tag="KNP54_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBF0891048.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(124114..124698)
                     /locus_tag="KNP54_000112"
     CDS             complement(124114..124698)
                     /locus_tag="KNP54_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBF0891049.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(124898..126328)
                     /locus_tag="KNP54_000113"
     CDS             complement(124898..126328)
                     /locus_tag="KNP54_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0891050.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            126646..127590
                     /locus_tag="KNP54_000114"
     CDS             126646..127590
                     /locus_tag="KNP54_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBF0891051.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            complement(127861..128796)
                     /locus_tag="KNP54_000115"
     CDS             complement(127861..128796)
                     /locus_tag="KNP54_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBF0891052.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNKIDDTLKARNSYQGCKFV"
     gene            complement(128915..129508)
                     /locus_tag="KNP54_000116"
     CDS             complement(128915..129508)
                     /locus_tag="KNP54_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBF0891053.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            129615..130043
                     /locus_tag="KNP54_000117"
     CDS             129615..130043
                     /locus_tag="KNP54_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBF0891054.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            130110..130778
                     /locus_tag="KNP54_000118"
     CDS             130110..130778
                     /locus_tag="KNP54_000118"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBF0891055.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREELVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(130896..132251)
                     /locus_tag="KNP54_000119"
     CDS             complement(130896..132251)
                     /locus_tag="KNP54_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0891056.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(133118..133504)
                     /locus_tag="KNP54_000120"
     CDS             complement(133118..133504)
                     /locus_tag="KNP54_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891057.1"
                     /translation="MNNNKFVAPNNVTLVERCYRYIKDRECSFSPNTIRNRKNMIKNQ
                     IEVFFKDMKLIDITPSILQSYINNIYNEHMLNSIKNQVDFIKSVLKESYRLKEISENI
                     CDFVTTPIKKVVQLLSFIQNKKLNYY"
     gene            133537..133683
                     /locus_tag="KNP54_000121"
     CDS             133537..133683
                     /locus_tag="KNP54_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891058.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            complement(134436..134681)
                     /locus_tag="KNP54_000122"
     CDS             complement(134436..134681)
                     /locus_tag="KNP54_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891059.1"
                     /translation="MNQKKIKISIKMVIIGIFSVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIIFANCIMFSNILLEIFLIYICRKFRKI"
     gene            135306..135410
                     /locus_tag="KNP54_000123"
     CDS             135306..135410
                     /locus_tag="KNP54_000123"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBF0891060.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     repeat_region   135940..136426
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=135940..135968
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            complement(136752..138485)
                     /locus_tag="KNP54_000124"
     CDS             complement(136752..138485)
                     /locus_tag="KNP54_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBF0891061.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     gene            complement(138725..139570)
                     /locus_tag="KNP54_000125"
     CDS             complement(138725..139570)
                     /locus_tag="KNP54_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0891062.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            complement(139601..141835)
                     /locus_tag="KNP54_000126"
     CDS             complement(139601..141835)
                     /locus_tag="KNP54_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0891063.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
BASE COUNT        54835 a        16364 c        23423 g        47655 t
ORIGIN      
        1 aataatagtt agatttttta tatgaatttt aataggtaaa atatcctatt gttttgtaga
       61 tatatcctaa ttatgtcaaa aaataaaaaa atttttattt attagagttt ttggaaataa
      121 taataacaga tattataatt aattaacagt ttttgtaagt atttgacaat agagagggtg
      181 taacaaatgg gaataataga gtcagcatca aaattggctg agatggttca tttattggct
      241 gttgaaaagg ggataactga tatagaagca tgggatgaag ctgtgaaaga atacagcaaa
      301 atttatgaag aaagaagaaa tgaatagaat gataaaaaat gaaaacttga tgataaaaaa
      361 taactttatt taaagaaatt caatttttat agaagtatta aaaataatat aaataaaaag
      421 atggtatttc aaatgtaagt aaaaaatcat tttgggatac catccttatt atttatttta
      481 ataatatata agtaataaat cttacttatc catatttttt atgtaacctc ttttttctaa
      541 cttttttata tgctccttac gtatttcatc aagattaata ccatattgtt cttctagctt
      601 aaacatcata gtaacacatg tctgagctac atccattagt tccttagcag ttttctttat
      661 aatatcaact tcatctaaat cattattttc tccacttaga tttctgaatt tacctataca
      721 ttcagctaat tcaccttgtt cttcacccat tttgataaat gtagattcta gtgttgggtc
      781 taaattatta agctctggta aagatatagt ttttagtttc ataaaagctc ctttcaagtt
      841 attcgtattt atactaaaac atcataacaa aaataatact aaaaaaaaac tttaaattca
      901 acataaaaac ttacatatat aataaaaatc gtgaaataaa tctatatttg tcttaataca
      961 gcctcatata aaacttctcc aataggttta tttattacaa gagaagctga cttatcatag
     1021 actgtatttg ctttattaat aagagcaata taatcacctt tgtaataatc tataaaactt
     1081 gctgctgggt acacagctaa tgatgtacct cctataatca ataaatcagc attacttata
     1141 gcagaaattg ttttagtaat gacatcactg tcaagagctt cctcataaag tactacatct
     1201 ggttttacta tagaaccaca gttgtcacag taaggaatat tacctcccag atttaacata
     1261 gattctaagt caaaaaactt accacattta gtacaataat ttctatgtac agaaccatga
     1321 agttctagca catttttact tccagccatt tgatgaagtc catcaatatt ttgagttatg
     1381 acagctttaa gcttacccat ttcttcgagt tttgctaaag ctatatgagc attattgggt
     1441 tttgcattag gatatattaa tttatcctta taaaattcaa aaaattcttc tggatatcta
     1501 acaaaaaaag tatgtgaaac taattgttca gcagtaaatt gtttattgag tttttggcta
     1561 aataatccag tagaacttct aaagtctgga atattagatt cagttgaaac acctgctcca
     1621 ccaaaaaata caatattatt gtgattagct attaagtctt ttaagctatt tgcatccata
     1681 gttacacctc caaattatta tatataaatt gtactacata ttaggtcgtt tatgttttat
     1741 taatttaaat aaatatatag tttaataagt taaataaagg gaatataaat aaaatgtata
     1801 cagagtataa atagacaata tttactaaaa taacaagttg tcgtataatt atattaaaat
     1861 tgttttagtg tataagaagg gcgggggaag tacgtgaaga aaaaagcagc tttagcaaca
     1921 ttggctatgt tacccttagg tgtggtaaat gcacatgctg atggagatat aggtatagtg
     1981 actataaatt atttaaatgt aagaaatgaa ccaactgccg aaagtagcat agcctttgtt
     2041 gctaaaaaag atgataaagt tttgattaaa gactcttcta atggatggta taaaataaaa
     2101 gctgaatctg gacaagaagg ttgggcttca tcaaaatata tagcaaaatc aaatagtgac
     2161 tctttaagaa cgtctacaaa taaagaaaaa caagttattt caaatagttt aaatatgaga
     2221 aatggagcag gtacaagtta cagagtaata actgtactaa aaaaaggtca aaaagtagaa
     2281 gtaatatcag agagtaatgg atggtctaaa atcaaatatg atggaagact aggatatgta
     2341 tctagctctt atttaggaga cgtttcaaac tcaactaata aatcaaaaac taaacaagtg
     2401 aatacaactt cactaaatgt aaggagtgga ccaaatacaa gttatggttt gttaggcaag
     2461 ttgccaaaag gaagtaaagt agaagtaata tcagaaggta atggatggtc caaaataaag
     2521 tataatggaa aagatgccta tgtatctagt atgtacttat cggatgtaag tcaaagtaat
     2581 tcagacaatt ctagtcaaag caatgataaa aagaatactg ataaggtcgt aaatacagct
     2641 tctttaaatg taagaagtgg accaggttct acatatagta agttgggaaa agtttataaa
     2701 ggaagtaaag taactgtact atcagaaagt agtggatggg ctaagattaa ttttaacaat
     2761 aaagaagcat ttgtagtagg caattattta tctacttcag cagatacttc aaataataac
     2821 tcaaatagta actctgataa cagttctaat agtaatggca ataattcttc atcatcaggt
     2881 caagtaaatg gtatgtcagg tataagtggg gctaaaattg attataaatc tttgagttat
     2941 actttagaat ctcatataag taaacaagtt gagaaagcag catcaggagg aaatgtgata
     3001 gctccaagta ataggaaaag cactccaagt cctgaattta gtactttttc agctcaaaga
     3061 acaagctcat ttgtaaatgc aagttcaagt gatatagaat attatttaaa tcctaaaaat
     3121 tttacaaata ctactaaagg tatgatgcag tttttaaaga ttaacagtta tagagatggt
     3181 atttcagaat caagtcttaa ctcgtatctt aatggtttat cttctagtgt atttaaaaac
     3241 cagggagcag cctttataaa tgctgccaag aagtataata tagatgttgt atatctagta
     3301 tctcatgcta tgtgggaaac tgcttatggt aagtctacac ttgcccaagg tcaaacatta
     3361 acatcttata agggacaacc tcttagtaag ccagttaaag tatacaattt ttttggtata
     3421 ggagcaatag ataaaagtgc taatgtttca ggtgcagaag cagcgtattc caatggctgg
     3481 actagtgtag aagctacaat agatggctct gcaaagtgga tatcacaaaa ttacgtaaat
     3541 agttctaagt acaatcagaa tactatctac aagatgaagt ggaattatga ttatacatgg
     3601 catcagtatg caactgatgt gaactgggct aatggaattt ctggaattat ggaaaattta
     3661 attggtcttt atggaggagg aagtagtttg gtttttgaag ttcctcaata caagtaatac
     3721 ataaataaaa aatatagact atgggtagtt ttcattttat ttaaattatc tatagtcttt
     3781 ttgtatataa tttataatct gtaaatttaa tgctaacaaa acttttatgt tataatatta
     3841 attctaagta aatataagtg agtaataggt agaaatagat aaaaagtggt aataatatat
     3901 ataaagataa ttttgagaaa ggaggatata tatggaaagt attaaggaat atttggataa
     3961 gttagaaatt aataatagtg gtcttggaaa gcaacttaaa gaagtttata taaatagagt
     4021 agtttatttt aaggaagata agatagttta tttttatcta acttctaaag atattgtttc
     4081 tcatgaactt ttagataaat ttaaagaaga attgatgtat aaactcgatt attttaaaga
     4141 tatgaggatg aagataagat ttactggtct tgaaagaaaa tccaataaag atgttataaa
     4201 aaaatattgg aataatatat tgtatatatt aaagtatctt tgtccatcta ttgcagggtg
     4261 gtataaacaa gtagaatttc tttgtttaga agaagaatta aaaataaaac ttccaaaagg
     4321 tatattttat gagcgattaa tgaaaaaaaa tgtaacttat gtacttaaaa ccgtgcttag
     4381 cgaagagttg ggattagatt taaatataac aatagaaaaa gctgttgatg aaaaggtaaa
     4441 taaagaaaga ctcataagaa tcaatgatag agaaatggaa gaaaaaatta gggctttaga
     4501 aattggaaaa gttaataact gtgaagaaaa tgaagaggaa agttatgtca ttaagtctga
     4561 tgtagatgaa aatttaatct atggagataa tgcaaatgct atgattgaaa atatagttga
     4621 attaaatgca tcttctggaa cagttgcagt tgttggagat atatttgatg ttgacactaa
     4681 agaacttaaa aacggaaaaa tacttatgat agcttcaatt acagattata ctagctcaat
     4741 aagctgtaaa ctttttttaa cagatacaaa taaggatgga gtacttgaaa atgttaaaaa
     4801 aggagcatac ttaaaaatca agggtgacat agtttatgat acatatcaaa gagaaattag
     4861 tatgatgatt agtgggataa gaaaagaaac tagaatagag agagaagata aatcagagga
     4921 aaaaagagta gaactccatg cacatacaca aatgtcttct atggatgcta tttgttctgt
     4981 taaaaagctt gtagagcgtg cagccaaatg gggtcattct gctattgcta taacagacca
     5041 tggtgttgta caaggatttc cagatgctat gaatgcaggt aagtcaaata atataaaaat
     5101 actttatgga gtagaagggt acttggttga agatgattct ctcattatag aggatgcaaa
     5161 tgataaagaa ctttcgcaga catttgttgt atttgacata gagacaactg gtttttctaa
     5221 tacaaatgat aaaataactg agattggtgc tgtaaaaata gaaaacttta agattgtaga
     5281 tagatttagt gagttaataa atcctgaaaa agatatttct tataagatac aggaattgac
     5341 aggaataact aatgaattaa ttaaagacaa gccaaccatt gaagaagttc ttcctaagtt
     5401 tatggaattt gttggagata gtgtattagt agcacataat gcagagtttg atactggatt
     5461 tatatcgcaa aaatgtaggg aacaaggctt gttatataat aacaaaaaag tagatacact
     5521 tatgttagca agagtaatgt tgccaaactt aaaaagacat agattaaatg tcgttgcaaa
     5581 agaacttggt attcctcttt taaatcacca tagagcagtg gatgatgctg aagctacagc
     5641 acttatattt aataagtttt tgcagatgct tacagaaaaa ggtgcaaaaa ctctaagtga
     5701 tgtaaacaat atacttggaa agattgatta cacaaagctt agcacaaatc atataacctt
     5761 gatagcaaaa aattctatag gtataaaaaa tttatataaa ataatttcag atgcacatgt
     5821 aaatcatttt tttagagcac caagaatcct tagaagtgta ttaaatgaat ataaagaagg
     5881 attaataatt ggttcggctt gtgaagctgg ggtggttttt caagctgtaa agaaaaacgt
     5941 gtctgatgag gaaatgaaaa aaataataga tttatacgat tatattgaag taatgcctat
     6001 agataataat agatttatga ttgataaagg agaagtaaag gacgaagaag agttaaggga
     6061 gttgaatagg aaattaattg atacagccaa aaaatttgac aaaattccag tagctactgg
     6121 ggatgttcat tttttagaca aacatgaagc tgtcttaaga aaagttctta aatattctca
     6181 aggttttaaa gtagatgaag aagaaactta tttacatttt agaacaacag atgaaatgtt
     6241 ggaagagttt agttatcttg gagaagaatt ggcatatgaa gttgtagttg aaaatagtaa
     6301 tctgattgcc gatatggttg aagatataaa acctatacca gatgatactt atcctccaat
     6361 tatagagggc tcagatgtgg agttaagaga aatgtgttac aaaaaagcca aacgaatcta
     6421 tggagaccca ataccagaaa tagttcaaaa aagactggat agagaattaa attcaataat
     6481 aagcaatggg tatgcagtta tgtatattat agctcaaaaa ctggttgcaa aatctctttc
     6541 agatggatat ttagttggtt caagaggctc agttggctca tcttttgcag ctactatgag
     6601 tgatataaca gaagttaatc ctcttccagc acattatatt tgtgaaaacg aagactgtaa
     6661 atattcattc ttttatgaaa taggtgaatg gggctcaggt gttgatttac cagacaagga
     6721 ttgtccaaag tgtggaagaa aacttgctaa aaacggtcat gatattccat ttgaggtttt
     6781 cttaggtttt gaaggtgata aagaaccaga tatagactta aatttctcag gaaattatca
     6841 gccaacaatt cataaataca cagaagaact atttggagag gggtatgtat atagggctgg
     6901 gactataggt actgtagcag aaaaaacagc ttttggatac gcaagaaaat atgtggaaga
     6961 aaataatata agtgtaccaa atgcagaagt acttaggctt tcaaatggat gtactggagt
     7021 aaaaagaacc tcaggacaac atcctggtgg agttatggtt ataccagact ataaagatgt
     7081 atacgatttt acacctatac agtatccagc aaatgatact tcttgtggtg ttataactac
     7141 tcactttgat tatcattcaa taagtggtag aatacttaaa cttgatatac ttggacacga
     7201 cggtcctacc attataagga tgcttgaaga tatgactgga ataaatataa cagaaattcc
     7261 tttagatgat aaagagacta tgtctctatt tacatctaca gaagcattag gtgttacacc
     7321 agaagaaata aactgtccta taggttgcct tgctgtacca gagtttggaa ctaagtttgt
     7381 acgacaaatg ttacttgaca caaaacctac tacatttgca gaacttgtac gtatatctgg
     7441 tctctctcat gggacagatg tttgggtaaa taatgcacaa gacttagtta gagaagatat
     7501 agttggatta aaagatgtta tatctacacg agatgacata atgaactatt taatatttaa
     7561 aggattacct cccaaaatga gctttacaat aatggagagt gtaagaaaag gtaaaggttt
     7621 aaaaccagaa cacattgaag aaatgaaaaa aaataatgtt ccagaatggt atataggctc
     7681 atgtaaaaag attaagtaca tgttcccaaa agcacatgct gttgcttatg taatgacatc
     7741 atttagaatt gcatattgta aagttcacta tccagaagca ttttatgcga cttattttac
     7801 gacaaaagtt gaggattttg atgcagattt aattgttaaa ggattagatg ctataaaatc
     7861 aaaaataaat gaaattgagt cactgggaaa tgatgcaacc acaaaagaaa aaggtatgtt
     7921 gaccgtttta gaagttgctc ttgaaatgta tgctagagga ataaaattat taccagttga
     7981 tatatataaa tcagatgcaa ctgagtttat agttgtagga gaaaaaacat tacttccacc
     8041 aatggcagca atacaaggtc ttggaggaaa tgcggctata aacatccaaa atgaaagaaa
     8101 aaatggtgaa tttatatcaa aagaagattt gagaaagaga acaaaaatat caaaaacggt
     8161 aatagaaact cttactaatc atggttcact tgagaatatg agtgagagaa atcaattgtc
     8221 attgttttaa gttagcccaa aaagttgcaa ataaaagaat tttatgatat catagtatag
     8281 aaaatagtat actttgcaga aactaagagt gagacagctg ttctcactct tttattttaa
     8341 atatattatt aaaaagctgg tttattttta ttaaatatat tttatttaag attatataaa
     8401 ctggtcattt acaattgaat aggaggaact ttaatgaaaa aaaatttaga agctacaatt
     8461 gaggagattg taactaaaat aacggatgaa catggatttg aaatggttga tgttgaatat
     8521 gtaaaagaag caggagaata ctacttaaga gtatacatag ataaagaaga aggaatatct
     8581 ttaaatgaat gtgaattagt tagtagagaa ttaagtccaa tactagatga aaaagaccct
     8641 ataaaagaaa attacttttt agaggtatct tctccagggc ttgatagagc attaaaaaaa
     8701 gacagagatt ttgttagata tcaaggtaga gatgtagatt taaaattata taaaccatta
     8761 aatggatgta agcaatttga aggtgaactt gtaggattaa cagaagataa taatataaaa
     8821 atcattgcaa atggtaagga aatggaattt aatagaaaag atgttgctat tgtcagatta
     8881 gcaataaagt tttagtggta tattaaatag ggaggatata aaaaatgaat catgaattta
     8941 tggaagcatt agatgaatta gtagttgaca gaggtataga taaagaaata cttatagata
     9001 ctatagaaca agctctttta actgcataca agaaaaactt tggttcagca caaaatgtta
     9061 gagttgaatt tgatagagac aagggagata taaaagtatt ttctcaaaga gttgttgttg
     9121 atgaatcaga tttatatgat actttcttag aaatagagtt agcagatgct agagagataa
     9181 accctaatta tgaattaggt gatattatag aacatgaagt tacacctaaa aactttggaa
     9241 gaattgcagc tcaaacagca aagcaagtag ttgttcaaag aataagggaa gctgagagag
     9301 aaatagtgta taatgaattt atagaaaaag aaaatgaaat agttacagga gaggttgcta
     9361 gagcaaataa aaatgttgtt tatgtaaatc ttggaagaat agaaggtata atgactcaaa
     9421 gtgaacaaat accatttgag aattataaag caggtcaaaa aataaaattc tatatacttg
     9481 aagttaaaaa gactaacaaa ggacctcaaa tagttgtatc aagaagtcat ccgggtctag
     9541 taaagagatt gtttgaagaa gaagttcctg aaatatatga aggaatagtt caaataaaat
     9601 ctgtagcaag agaagcaggg tcaagaacta aaatggcagt aagatctata gatgaaaaaa
     9661 tagacccaat tggagcttgt gttggaccaa aaggacttag agtaaaaaat atagtggatg
     9721 aacttggcga tgagaaaata gatataataa aatatagtga agacccagca gagtttatat
     9781 cagcagcact tagcccatca aaggttgtta gagtagatat agatgaagat gaaaagtctg
     9841 ccttagtaat cgttccagat tatcagttat cgcttgctat aggtaaagaa ggtcaaaatg
     9901 caagactagc agcaaaattg actaactgga aaatagatat taagagcgaa tctcaagcag
     9961 aacaagaaat gttaaatctt gaaaattcca aagaaataga agctgaggat gttgaagctg
    10021 aatttatcga ccaagaagag ttagatactt cagaggataa ttttagtgaa gaagagtaag
    10081 gagggatgat tttgaaaaaa gtaaaaaaag tgcctcaaag aaaatgcata gcatgtcaag
    10141 atagagactc taaaaaagag cttataagaa tagttaaaaa taaagaagga aaaatatttt
    10201 tagacccaac aggaagagcc aatggaagag gagcatatgt atgtaaaagc tctgaatgtc
    10261 taaaaaaagc tataaagagt aaagcattaa ataaagcttt taaaatagat gttcctgatg
    10321 aagtctatga taatctactt atggagttag aagaatatga aaaataataa agaaaaagta
    10381 ctttcgttct tagggctcgc aactcgtgca gggaaaatag tgtctggtga tgattcaact
    10441 ttgcttgacc ttaaaaaagg aaaagtaaat ttgattttaa tcgcagaaga tgcatcaaat
    10501 aatactaaaa aactttttaa agataaatca acttttagaa atattccata tctatttttt
    10561 tcaacaaaag aggaaatagg atttgcaata ggaaaatctc caagagcagt tgtaggaata
    10621 aaagatgaaa atttttctaa aaagataatt gaactaatag aaatttaaaa taaaataggg
    10681 ggtgatcttg tgtcaaaaac aagagtatac caaatagcag aagaattaaa tatatcaaat
    10741 gaagagctta taaataagtt agctgaatta gatataaatg taactgacaa agattcagta
    10801 ttagaaggtg aagagttaga attagcactt gaaatgttag gtgaagattt atctcaagaa
    10861 aatggaaatg ttatagaaat agatggaaag ttgacagtac aagtattagc aacgaaatta
    10921 gataaatctc catcagaaat aattatgaag cttatgaaaa tgggaactat ggcaacaata
    10981 aatcaagaga taagttttga gattgctgct ttggctgcca aagactatgg atttgaatta
    11041 acagtagctg aaagtgatga tacagaagct ttagaaatag aagctttaat ggaaattgaa
    11101 gaagataaag aagaggattt aaaacctaga ccaccagttg ttacagttat gggacatgtt
    11161 gaccatggta agacatcttt actagatgca ataagaaaaa ctgatgtgat ttcaggtgaa
    11221 gctggaggaa taactcagca tataggtgct tcagaagtta aaatcaatgg acacaaaata
    11281 gtatttttag atactccagg acatgaggct ttcacatcaa tgagagcaag aggagcacaa
    11341 gttacagata tagcaatatt agtagttgca gcagatgatg gtataatgcc tcaaacagtt
    11401 gaagctataa accatgctaa agcagcaggt gtacctttaa tagttgctat taataaaata
    11461 gataaaccag gtgcaaaccc agataaggtt aaacaggaat tagcagacca aggattatta
    11521 gttgaagact ggggtggaga agtaatagca gttccagtat cagctaagaa aaaagaagga
    11581 atagatacac ttttagaaat ggtattattg gttgctgaaa tggaagagtt aagagctaat
    11641 ccaaataaaa gagcagtagg aactgttata gaagctgagc ttgataaagg aagagggcca
    11701 gttgcaacag tacttgttca aggtggtact ttaacagtag gtgacccaat cgttgcaggt
    11761 gttgcatgtg gtaaagttag agcaatgata aatgcaaaag gtaagagagt aaaaacagca
    11821 ggaccatcta cagcagtcga gatattaggt ctatcagaag ttccacaagg aggagaccaa
    11881 tttgtcgaag ttccaactga taagattgct agaagtgtag cagcaagaag acaacaaata
    11941 gttagagatg aaatgttaaa atcaactcaa agattatcac tagatgctct atttagtcaa
    12001 atgagtgaag gttctataaa agaccttaat atagttataa aagcagatgt acaaggttca
    12061 gtacaggcag ttaaacaatc tttagaaaaa ttatcaaatg aagaagttca agttaaagta
    12121 atacatggtg gtgttggagc tgtaacagaa tcagacatat tacttgcagc agcttctaac
    12181 gcaataataa taggattcaa tgtaagacca gttccaggtg cagaatctct aggagaaaaa
    12241 gaaaatgttg atataagaac atatactata atatacaagg caatagaaga tatacaagcg
    12301 gctatgactg gtatgttaga ccctgaatat gttgatgaag aaacaggaaa agctgaaata
    12361 agagaaatat ataaaatatc tggtgttgga acagtagctg gatgttatgt gactaatggt
    12421 aagatattta gaaattgtaa agtaagatta gttagagata gcataataat acatgaaggt
    12481 gagcttgcag cacttaagag atttaaagat gatgtaaaag aagttaattc tggatacgaa
    12541 tgtggtatga gttttgtaaa ttataacgac ataaaagaag gcgatatagt agaagcttat
    12601 ataactaaag aagtagaaag aaaattataa attcgtatca aagaaaatca gttagtaaag
    12661 aaggtcgatg gtatggcatc atataataga acaagaagga tagcagaaga aataagaaaa
    12721 gtcgtaagca ctatgcttat aaatggagta aaagacccta gaataacatc tatggtgagt
    12781 gtaactgatg tagaagttac aaatgaccta agatatgctt atgtatatgt aagcattcta
    12841 ggtggagatg aagaatccac actaacaggt cttaaaagtg ctggaggata tataagaaga
    12901 gaagtaggaa aaaatataaa acttagatat attcctgaaa tagtatttaa acttgatgat
    12961 tcaatagaaa aaggaatgta tatggatagc cttataaaaa gagttaatga aaaaaatgct
    13021 caacaaaatg aggatgaaaa ttatgatgaa taatatggat agtattataa actatattta
    13081 tgagggtgac tattttatag ttacctctca tatcagtcca gatggagaca atattggttc
    13141 tacactttca atgtattata cattgaagaa tttaggaaaa aatgtatatt atgtacttga
    13201 tgatgaagct ccattaaatt taaggttttt ggttgaagat gtaaaaatct ataagtctaa
    13261 tgaatttaat atgaagaact attctctaat tgcacttgat tgtggggata agatgagaat
    13321 atgtgtgagt gatgaaatca aaaataatgc atcaaaatta atctgtattg accatcatgc
    13381 tagtaatgat tcatatggag atttaaatta tgtagatatt gatgcatctt ctacatgtga
    13441 attagtttat aatttattag ttagatttca gcaaataaaa gatattaata ttataaatga
    13501 agatatagca acatgtttat atacaggtct tgtaactgat actggaaact tttcgtattc
    13561 aaatgtacat gcaagtagct ttgaaatggc aaaaaattta cttgttttag gtgcacaaaa
    13621 aaatactata atacaaaata tatatcaaag caattcttct ggttattaca aattattagg
    13681 agaagctcta aagggtttgg agatatttga ttcaaaggta tctagtatag ttttaactca
    13741 agacatgatg aatagaaata atattagctt taatgatgtt gatggaataa caacatatac
    13801 aagagacata aaaggtatag aagttggaat tttatttaaa gagaaaaaac aaaatgaaat
    13861 taaagtgagt tttaggtcaa aaaattatgt tgatgtaagt gaaatagcca agttatttgg
    13921 tggtggtggt catgtaaggg ctgctggatg tactattaga gatagtattg ataatgcaaa
    13981 gaaaatggta ctagaggcag tgttaaaatc aatttaaggt gacagtaaaa tgaataagat
    14041 tataagtata ttgaaaccca caggtatgac atctcatgat gttgtaagta gagtgagaaa
    14101 gattttaaat ataaaaaaag ttggtcatac aggtactctt gacccagatg cttcaggtgt
    14161 tttaccaatc tgtataggga aagctacaaa agtatgtgaa gttattttaa acaaagataa
    14221 atcgtatata tgtgagctta ctttaggtat aagtacagat acttatgatg cttcaggtga
    14281 aattttaaaa aaagttgatg attttaaatt tagtaatgaa gacatagaaa gagcttttga
    14341 cacacaaaga ggagagataa atcaacttcc tccaatttat tcagctttaa aggtaaatgg
    14401 aaagagaatg tgtgatttag taagaagtgg tagacaatct gaaattactt taaaaacaag
    14461 aagagtaaat ataaaagaca taaaaatact aagtataaaa ggtaataaag taatgtttta
    14521 tgttgagtgt tctaaaggga cttatgtgag aagtatttgc catgatatag gagaatatct
    14581 aggttgtgga gctcatatgt cgtttttgaa tagaacatct tctggtaaat ttgacttaga
    14641 taattcaata acattagaag aattagaatt attttatgaa aataaaactt tagacaaata
    14701 cttatatgat atagattatg tccttgattc gtttaattat gttgtattaa accctaatgc
    14761 tataaaatat tatagtaatg gtggctcaat agatgataaa aggtttttaa agaataattt
    14821 cgataaagat gatgaatttg taagagtata cagtacagat aatttcttag gattaggaaa
    14881 gttatcaaaa cacaataata caataagtgt taaaagtgat aagatgttca tataaccaat
    14941 gtatttaaaa aaacaacaaa agagatagta ctataataac ttctatagtc tatctctttt
    15001 acttatgcta taatagtttg tgaataagtt aagagtaaat tatattttag cggggaacat
    15061 ttattatggt gattataaaa tctataaaag aaatagcaaa cataaaagaa agtgtcatta
    15121 ccataggaaa ttttgatggt gtacacaaag gacatcaagt tcttatagga aaaacagttg
    15181 aacatgcaaa aaaagaaaat atacagagta ttgtatttac atttgcaaat catcctgtaa
    15241 attactttag accaaactca acaaaaaata ttataagcaa tgatgataaa ataaaattat
    15301 tagaagattt gggaatagat atagttgtaa tcataccatt tgatgagtat atgactaaaa
    15361 tacctgcaaa ggatttcgta gatgagatac tagtaaaaaa attaaaagct aaaaagatag
    15421 taattggaca tgactttaca tttgcaaggg caaaagaagg caatgttaat ctattaaaaa
    15481 gcttagaaca tgaatttggt tttgaggtag aagtaataaa acccatcaaa atcaatgatg
    15541 taagagtgag tagtacttat attagaagtt tagtatccca gggtgatatg gctaatgtca
    15601 aggaatattt gggtagaaat tacaagttag aaggttgtgt tatacattct aaacaccttg
    15661 gaagaactat aggattccca acggcaaata ttgaccttaa gaataatatg ctcgttccaa
    15721 agagaggtat ttatgcttct attgtacata ttggagatga gacttatttt ggtgctacaa
    15781 atgtaggcta taacccaaca gttaatggaa aaactttgtc tattgaaaca aatattttag
    15841 agtttgatag agatatttat ggggaaaata taattgttga atttttggaa agaataagag
    15901 atgaaagaaa gtttaattca atagatgact taaaaaatca attgtataat gatacaaatt
    15961 atgtgtatga aaactatgtt tgcaaaaaca agtaatgtat gataaaatga ttaaggaaaa
    16021 taaccattac tcggcatttg aatactccaa tcaatgctta gtaataggcg tttctaaaaa
    16081 aatacggagg taatctaaat gataaacaaa tcagaaataa taaaagaata tggaagagct
    16141 gaaggggata ctggttctcc agaagtacaa atagctttat taacagctag aataaacgag
    16201 ttaaatggac atttaaaaac tcataagaaa gaccaccatt caagaagagg actattaaaa
    16261 atggttggta gaagaagaaa cttattagct tacttaaagg aaaaagatct tgaaggatat
    16321 agagcattaa tagctaaatt aggattaaga aagtaatttc attctttata aaaaagcagg
    16381 tatagtgtat acctgctttt ttatagttaa ttcattataa agtaaaatag ttaataataa
    16441 aagtagttta tatgttataa aaaattataa aatgaataat attgggtaag aatattaaaa
    16501 tagtatacaa atacataatc aatttaaaag gaaagacagg ataaatatag aaattttata
    16561 acaggataat tagttggaat aaggaggata ttattttgaa aataaagtta gtatgcgata
    16621 gtttgtgcga tattccagat gaaatatcgg aaaaagatta tatagagata gttccactta
    16681 cagttatttt taatgatagg gaatatatag aaggagtaga tataaagaaa gaagagtttt
    16741 ataaaaaagt aaaagaaatc aagcaaatac ctaaaacttc acaagctaca tatatggagt
    16801 ttaaagaagt gtttgataag ttcataacag aaggttatca tataatctgt atgacagggg
    16861 ctgcaaacgc atcaggaact tttcaaagtg ctatgatagc taaaaatgat gtaaatgaaa
    16921 atgaaaaaat acatatattt gatactagaa atttatctct aggtagtgga caatatgtta
    16981 taaaggcatg tgaacttctt gaagaaggac tgggatttga agaaattata gatgaattag
    17041 aaaatactcg cagtagtgta agattgcttt ttgcaccata tacacttgat tttttaaagc
    17101 agagtggaag agttccagtt gcaactgctt tgataggaaa tatgttaaat ataaagccta
    17161 tatttttctt tgataatggg gaagctaagt tggtaaataa ggttagagga ataaagaata
    17221 tagcaagtaa attggtcgat ataattttag aaatgaatga agggtcttta gaaggaaaaa
    17281 tcgtcacaat aggttgtgga gataatttac acgattgtga aatattaaaa gatgaagtaa
    17341 ataaaagaat aaaagcaaga agagtattat ttactcgagg aggagtttct atttgctctc
    17401 atacaggacc agatatattg gctataagtt gttctaatta gtagtaatat aaggtttttg
    17461 catatatatg tgaagataat tttatattgt taatttatag tatttttgat aatatagtaa
    17521 atagagtgat atacgtgttt tttaataaga ggaggacaag cattaatgtt tgaacataaa
    17581 atatttaaaa tggattttgc aggaagagaa ctttctgtag aaataggaaa gatttgtgaa
    17641 atggctagtg gtagttgtat agttcgatac agtgatagta tggtaatggt aaatacaact
    17701 aaatcagcca aacctagaga cggaatagac ttttttcctt taagtgtgga ttatgaagaa
    17761 aaattatact ctgtaggtaa gatacctgga ggttttttaa agagagaagg caagccttca
    17821 gagaaagcta tacttacatc aagattgata gatagaccaa taagaccttt attcccaaaa
    17881 ggatttagaa atgatgttca ggtagttgca acagttctat cagtagacca agattgtaca
    17941 ccagatatag tagcaatgat aggttcttca atagcccttt ctatatcaga cataccattt
    18001 aatggaccaa caggttcagt atgtgttggc cttgtagatg gtgcatttgt tgtaaatcca
    18061 aacgcagagc aaagagaaaa aagttcaatg catctagttg tttcaggtac aaaggaagca
    18121 ataatgatgg ttgaagccgg agctgatgaa gttccagatg aggtaatgct tgatgctatt
    18181 ttatttgctc accaagaaat aaaaaaaata gttgagttta tagaaggtat agttgcagaa
    18241 gttggaaaag aaaaaatgcc tgttgaatta taccatgcag gagaagaaat aactcaattg
    18301 gttcgcgaat ttgcaactga taagatgaaa aaagcagttc agacttttga aaagttagag
    18361 agaatggaaa atatggatag agttaaagaa gaaactttag ctcactttga agaaacttta
    18421 gaagattttg aagattttgt tggagatata gaagaagtat tacaagatat aataaaagaa
    18481 gaagtaagaa aacttatagt acatgaaaat gtaagaccag ataatagaaa acttgaagaa
    18541 ataagaccta tatggtgtga aactggcatg atacctagag ctcatggttc agccatattt
    18601 actagaggac aaactcaagt acttaatgtt gctactttag gtgctttagg agatgttcaa
    18661 aaactagatg ggttagatga agaagaaaac aagagatata tgcatcatta taatttccct
    18721 gcatatagtg ttggagaagc tagaccatca agaggtccag gaagaagaga aataggacat
    18781 ggtgctttag cagaaagagc tttattacca gtaataccat ctcaagaaga atttccttat
    18841 gctattagat tagtttctga agtattaagt tcaaatggtt ctacatctca agcaagtgta
    18901 tgtggttcaa cattatcttt acttgatgca ggtgtaccta taaaagatat ggttgcaggt
    18961 atagcaatgg gacttataaa gcatgatggt aaggttgcag tgctttcaga tatacaaggt
    19021 atggaagacc atttaggcga tatggacttt aaagtagctg gaacagagta tggtataaca
    19081 gcaatacaaa tggatataaa aattgatggt atagataaag aaattctaca acgtgcttta
    19141 aaacaagcta aagagggtag aatccatata ctaggagaga tgagaaaaac tatatctcag
    19201 ccaaaaccag aactttcacc atatgcacct aagattgtta aaatgcaaat aaatcctgac
    19261 aagataaaag atgtaatagg acctggtgga aagataataa ctaagataat agacgaaact
    19321 ggagttaaga tagatattga acaaactggg gaagtattta tatcaggtat tgagattgat
    19381 atgattaaga aagctcaaga acttataaat aatatagtag ttgaaccaga agtaggaaaa
    19441 acttataaag gtaaggtaag tagaataatg aactttggag catttgttga gatacttcca
    19501 ggaaaagaag gattacttca tatatctcat atagctcatg aaagagttgc caaagttgaa
    19561 gatgtattga atatagggga tgaagttgaa gttaaagtta cagagattga tgaaaaagga
    19621 agagttaatt tatcaagaaa agttctttta ccaaaaccag aacataaaaa taaataactt
    19681 attatataat taaaagcaaa gtcttaggat tttgcttttt taaatacaaa aaagtagata
    19741 attttaaaat gatagttatg gatggcttat agttcttttt ctgtcagtct ttactcttat
    19801 aaagaagcta tttaaaagct gattaataga aagctttatt gatatatata gaatcactta
    19861 agttatattt agtgcataaa cagagcttat ttttaatagt attaaataag aaacaatttg
    19921 tacataatta gggggagttt taatgataat gatggtactt aataagagta agctcaaaaa
    19981 aatcataata ctaattttag tagtgttatt agtattatca ggaggggtaa tggtattaaa
    20041 gttatttaac aacaagccag tatttaattt atttaatggt gtagatttac catatgaaag
    20101 aggtacaaag gataaaagtg gatatgttgc attaacctgt aatatagacc ttggatggga
    20161 aacagagtac gtagaatcca ttttagaaac acttaaaaaa gaaaatgtaa agattacatt
    20221 taatgtaact ggaaaatggg cagaaaagaa taaggatgaa ttattaaaga taaaaaaaca
    20281 aggacatgaa ataggtaatc atggatataa acatttagat tattctacat tatcatatga
    20341 agacaattat gagcaaatag agacctctaa aaagataatt gaagaaatta taggtgaaaa
    20401 aactaaattt tttcaagcac cagcaggttc ctttggtcca gaaacagtaa aggctgctaa
    20461 agcattaggg tatacttcta tcaaatggga tgccgatact atagattgga aatacaaaga
    20521 ccaaccagag gtaatcattg atagaatgaa gaaaaaagac attaaagata gtagtataat
    20581 cttaatgcat ccaaccaacg caacgacaaa atgtatagat gatattatag ctattgtaag
    20641 agaaaaagga ctaaaagcag gaaaacttag tgatgtattt aagtagacaa agtataaata
    20701 tttggttaag attgtataag ttgtagttga attaattaaa agactgactt ataatgtaat
    20761 acatataaaa aataaatata attaaaacat agtgttttca ataatccaat atgaaacaaa
    20821 gaataaattg ttaggagaat gtaatgtata agacaaaaat actggaaaat gggcttacaa
    20881 taattggtga agaaatacca tatctaaagt caataacatt aggtatttgg ataaatgcag
    20941 gctctaggat agaagaagca caggtgagtg gaacttctca ttttatagag catatgatgt
    21001 ttaaaggaac caaaaacaga acatcaaaag agattgctag ttcaatagat aatttgggtg
    21061 gtcaaataaa tgcatttaca agtaaagaat gtacatgtta ttatgtaaaa ctaatagatg
    21121 agcatataga tacaggaatt gatgtattga gtgatatgat actaaattct aaatttgata
    21181 aaaatgatat agataaggaa agacttataa tattggaaga acttaagatg tatgaagact
    21241 ctccagatga cttatcttat gatttattag tggaaaatat atatgctaat gatggattag
    21301 gaatgaatat aattgggaca aaagaatctc tatacaatat aactagagaa tccatgttag
    21361 aatacttaaa taagtattat attccaaata acgctgttat ttctatagct ggaaacttta
    21421 actttgatga tatggtggag aaaatcaaat caaaatttgg acactgggaa aagaaaaatt
    21481 tgagtataga cataagtgag gctaagttta atccttgctt tatatcaaaa aataaagata
    21541 ctgaacaggt gaacttagct atgtgcctaa aaggtattcc ttttgaaaat gatgaagaag
    21601 tctattcaat ggcagtggta aataatattt tcggtggaag tataagctca aggctttttc
    21661 agaaaataag ggaagaaaaa ggtttagtat attcaatata ctcatcacag acattatata
    21721 ggaaatgtgg tgaattaggt atatttgcaa gcatgagtac agaaaattta caagatgtat
    21781 ataatttaat aaagaaagaa attgaaaata taagagaaaa ctatcttaca gaaaaagaaa
    21841 tatctgaaag caaggaacag ttaaaaggaa attatatatt ggatttagaa agtactagca
    21901 gtagaatgat gtctactggt aaatctatgt tacttagtaa aaaagtaaaa actacagatg
    21961 aaatacttga atgtataaat agtgttaata ttaattcaat aaagaaggtt gttgataagg
    22021 tattcaatat cgaaaatatt ggtacatgta tagttggaag agatgtagaa aagattctac
    22081 acttggatta atattgaaaa aagtaaatct ctggaggtat aaaatatgaa tttatctgaa
    22141 atagcaggta aggaaatagt taacttggtc acaggagaaa gattgggggt cattggagaa
    22201 tgtgacctta tactagatga aactacaggc ggtatattag cgcttctaat tccaaaagaa
    22261 aaaggatttt ttgccagaag aaaagataag tcatttttag aagtaccatg gagaaatgta
    22321 aaaaaaatag gtaatgacat gataattata gaatatgagg gatatattta ggaggaaaaa
    22381 atgagtattt tagtgcaaaa gtttggtggg acatcagtag aatcatatga aaaaatgaat
    22441 gaagtatgta agatagtaaa agcatacaaa aaaaatgatg aagaattaca attagtatta
    22501 gtagtttcag caatgggaag aaaaggagct ccatatgcta cagatacact tataaatttg
    22561 tgtagtgcag taaatgatga gccaagtaaa agagaacttg atttaataat gtcttgtgga
    22621 gaaataatat caggaacaat tcttgctaat ttattgaatg cacaggggat agattctgtt
    22681 ttctttactg gtcagcaagc aggtataatt acaagtgatg aatattctaa tgcaaagata
    22741 aagtatataa atcctaaaaa ggtaaaaaga gctttagatg atggtaaggt tgtagttata
    22801 gctgggttcc agggtgtaac agatgatgga gaaataacta ctcttggaag aggcggaagc
    22861 gatacatcag cagttgctat tggtaaagct ttagaatgtg aaacagttga aatttacact
    22921 gatgtggatg gtataatgac tgcagaccct agagtagaac caaacgctaa agtattgagt
    22981 tttatagact atgaggaagt attccaaatg gctgacaaag gtgcaaaagt aatacatcca
    23041 agagcagtac agttggctaa aagtggaaat ataactttag ccataaagaa tacaatgaat
    23101 ccaacttttg aaggtacaaa aataggttct ttatgtagac acttagaaga caatatagaa
    23161 tatgaacaag aaagagattt taaggttgct gttgcaaata aagatagcgt agcacaagtt
    23221 aagattaagt cagcagaaga agtgtttaca gaagtattaa atgagataga aaagaaactt
    23281 ataactatag atatgataaa tttctttata tcagaaaaag catttgttgt agaagatgct
    23341 gatataaaat cattaaagga aatactagat aaatttgaat tagattatga agtaaataga
    23401 gactgtgcta aggtaacatt gatatgttca agaattgctg atgaaatgtc tggtatcatg
    23461 tcaaaggtag ttagaggatt atcaaaagca ggggtatccc ttttacaaac atcagactca
    23521 aatatgacta tatcttgttt agttagtgaa gaagatatgc atacagcagt acatgctata
    23581 catcaacaat tttatttaaa ataaactgta taatacaatt attttttaat caaatttaag
    23641 aatttcatat atatcttaat atatttgatt tatttggtaa aactaaatta aatataattt
    23701 tgataggagt ttttttatga aagattatag agaagataat gaaagatttg ataaagataa
    23761 ttgtagtgaa gaatctagtt gcgaagagag agaatgtata aagcaatttg gtaccaatga
    23821 aatgccacct caacctccta aagatattca atgtataact ataattggag aaattgaggg
    23881 acattttata ggaaatcctc aaaaaaaagc tacaaagtac gagcatataa ttccaatgct
    23941 atactcaatt gaggaaagta atgatgttaa aggagtgtta gttgttttaa acactgttgg
    24001 aggagatatt gaagcaggtt tagctattgc agaactttta aacagtacat ctaaaaaagt
    24061 agttactctt gttctaggag gaagtcatag tataggtgtt cctcttgcta cagcaggaga
    24121 ttactcattt atagcaccaa cagcaaccat gattatacat ccagtgcgaa ctactggtct
    24181 tgtgattggg ataaatgaga cttttgagta ttttaaaaag atgcaagata gaataattca
    24241 atttataata agaacatcaa atatcaaaaa agatgtactt gaaaaactta tgcatgaaaa
    24301 agatgaactt gtaagtgatg ttggtagtgt attaatagga aaagaagctg tggattatgg
    24361 tcttatagat gaagttggag gactaaaaga agcacttaaa aaattaagag agcttataaa
    24421 agaatctgag gaagaaaaaa ataatgatta aaatttgttt aaataataaa atttatgata
    24481 taatgatgta ataaagtagg agtgttagtg ttaaggcatt agcacttttt gctgtgaagg
    24541 ggtaaaactt gctaaaaata aggagtgata ttaatggcca cgaaaaagaa gaaaaaaaag
    24601 aaggtaaata ccttaagttt taatgcagaa tatcataatt taataacaat atttataggt
    24661 gtatttttat tatatagttt aaattctaat tctatgggat ggatacctgt gttaatgcaa
    24721 aatcttttta agggactatt tggagggctt tcaatagcaa taccatttat agtaattata
    24781 acaggacttt taggattttt tgatggaaat gaatatatat ataggctaag aaagactaaa
    24841 ctatactaca taattatttt atttatattt gtattttatg gattattaaa tgcaggaact
    24901 cttcctgtag atagcccact aaaaggtaac atgtttgatg atgttatgaa attgggtgta
    24961 agtggacaag gtagtggttt gatagcaaca actattgcgt attatatgag taaaatattt
    25021 ggtatagcag gtggatggtt aataagtatc ttcgcactta tactttctgt aatgtttata
    25081 tttaatattt ctataaaaga tttggtgtca aatgcaaaat caaaatctaa agcatctaaa
    25141 gacagcaatt taacgtttaa agataaaatt gcaaatatga aaaaatctgc aatagatatg
    25201 atgactgatg aagtagatga tactactata aataaaaaac caggtttctt taaagggtta
    25261 atgtcaaaag gtcttaataa tgatgatgaa gaagatgaat attttgaaga agaaaatagt
    25321 gatggtgtag atgataaaac tataaaaata gttggattta ataaggcaga agatgagtat
    25381 ttagaaatat tagaaggaac tcaaagtatg ccagagttag atgttttaaa agaattacaa
    25441 aaagctacca atgaaaatcc agttgtagat actaaaccag aaaaaaaagt tgatatagct
    25501 aaacctaatt taaatataga aaaaactcaa cctatgagta ttgtagcaga gccagttaat
    25561 gaggattatt caaactataa aaagcctagc attgagcttt taaataaagt aaataagaag
    25621 tctgatgaaa atggtaaaaa gaaagtgttg aaaaatgctt ctcttttaga aaagacacta
    25681 tcagattttg gagtggaagc aaaaattaat caagttacag ttggacctac tataacaaga
    25741 tatgaaatac aaccaagtcc aggagtcaag gtaagtaaaa ttgtaaattt aactgatgat
    25801 atagctttaa gtttagcagc taaaagtata agaattgaag ccccaattcc tggtaaaagt
    25861 gcaattggaa tagaagttcc aaatgaagaa gctcaaatgg ttggtgtgag agaagttcta
    25921 gaaagtgaag aatttaataa ttttaactct cctcttgcaa tgggacttgg aaaagacgta
    25981 gcaggaaaaa ttataattgg agatataggt aagatgccac acttactaat agctggttct
    26041 acaggttcag gaaagagtgt gtgtgtaaat acattaataa gtagtatttt atataaggca
    26101 aatcctgatg aagtaaaatt actattaata gacccaaaag tagttgaact tgcaaattat
    26161 aatggaatac cacatctatt gataccagta gttactgacc ctaaaaaagc tgcaaatgct
    26221 ttaaattggg cagttacaga gatgaataga aggtacaaat tatttgcaga tgctcaagta
    26281 aaagatgtaa caagttataa tgagaaagcg gaagaaaaac ttcctaaaat agtaataata
    26341 atagatgagt tagcagattt aatgatggca agtgcaaatg atgtagaaga ttatatttgt
    26401 agattagctc aaatggcaag agctgctgga atgcacttga ttgtagcaac tcaaagacca
    26461 tctgttgacg ttataacagg ggtaataaag gctaatatac catctagaat agcatttgca
    26521 gtatcatctc aaactgattc aagaacaatc cttgatatgg gtggtgcaga gaagcttcta
    26581 ggtaaaggtg atatgttatt ctatccactt ggtgcagcaa aaccagttag acttcaaggg
    26641 gcattcatat cagagagtga gtcggaaaaa gtaatcgatt ttgtaaaaag tcaagttaaa
    26701 gatggaataa aatatgaaga agatataatt gaaactatat ctaaggttaa tacttcaaag
    26761 ggtagtgatg aggatgagtt tttgagtgaa gcgatagaat ttgtcgtgga aagtggtcaa
    26821 gcatctgcct ctatgctaca gagaagattt aaaataggat tcaatagagc agctagactt
    26881 atagattcta tggaagaaag aggaataatt ggagcaagtg agggaagtaa accgagaaag
    26941 gtattaataa gcaaacagga tttgcagaat ttagaaggtg aatagaattg tcagttataa
    27001 aaatagaaaa agcacttaag ctagataaag taatatttgt agatgtgaga actgaaggag
    27061 aatatgaaga agaccatata ttgaatgcaa tcaatatgcc tctttttaaa aataatgaac
    27121 ataatgacgt tggaacaatt tataagatgc agggaaaaca tgaagcaata caaaaagggt
    27181 ttgactatgt atcgtataaa ttaaaggata tatatttaca agcagcagaa cttgcattaa
    27241 attatgataa tattgtcata tattgtgcaa gaggcggaat gagaagtggc agtatagtaa
    27301 atttattatc atcattaggt gtaaatgtat atcaacttga aggtggatat aaggcttata
    27361 gaaattttgt attagagtat ctaaggcatg taatggatac aaaaaacttt gtatctgttc
    27421 atggattgac tggtacagga aagactgatt tgttacattt attagatgaa aaaggaatag
    27481 atgtactgga tttagaaggc atagctaaaa acagtggttc tacctttggt tttataactt
    27541 ttgataaaaa gccaccttct caaaagaact ttgaaacaaa actatttgaa agtatatttt
    27601 tttcgaaaga gaattatata tttgtcgaga gtgaaagcaa acgagttgga agtgttacag
    27661 ttccaaatga aattttcgag gcaatgacac gagaaggaca tcatatatta ttagaatgtg
    27721 atattgaaaa tagagttgat agactttgta gagattatat ttatgataaa gatgaaggta
    27781 atatattgat tttaaaagaa tgtataaaca agtttagaaa aagattgggt aataaagtag
    27841 tagatgatta tattgattta ttagaatcag gtgaatataa agaacttgta aaaagatatc
    27901 ttttagaata ctacgaccca ctttatatgc attcagtaga aaaatataag tatagtaaga
    27961 ttataaattt taatgataca caaaaagctt tagaagatgt tatagactta tatgagagta
    28021 tattggaagg agaaagtgaa tgttaaaaat agcattagaa tcattaggat gctcaaaaaa
    28081 tttagtagat gcagaaataa tgatgggaat tttaaataac aaaggctata aattaattgg
    28141 agattttgaa gaagctgatg taattatagt aaatacatgt ggatttatag agtcagctaa
    28201 acaagaatct atagatacga taataaactt tgcagagtta aaaaaaactg gcaatttaaa
    28261 gttgttgata gtaacagggt gtctagccca aagatattct gaagaattaa aaactgaaat
    28321 tcctgaaata gatgctatag taggaacagg aagctatcaa aatatagata aaatacttaa
    28381 agaattaagt gaaatgcata aaattgtaag ccttaatgat atagagtttg tatttaatga
    28441 agatttacca agatatatat ctacacctag ctatatggcc tatttaaaaa ttggagaagg
    28501 atgttccaat aattgtactt attgtataat accaaaacta agaggtaaat atagaagtag
    28561 aaaatttgaa gatataatta aagaagctaa gaaattagct gaatctggag taaaagaact
    28621 tgtggttata gcacaggata cgacaaagta cggttttgat ttatatggaa aagaaagatt
    28681 atcagaactt ttagaagaac ttgcaaaaat agatggattt aagtggataa gggttatgta
    28741 ttcatatcca gaatctataa cagaagaatt gatacaagtt ataaagaaat atgataatat
    28801 atgtagttac tttgatatgc caatacagca tgcaagtaac aatattttaa aattaatgaa
    28861 tagaaaaact actaaagaag atatattaaa taaaatcaat ctgataagaa gtaatatacc
    28921 agatgctata cttagaacta caataatagt agggtttcct ggtgaaacag aagatgactt
    28981 caaacaactt gtggactttg ttgaagaggt taaatttgat agacttggtg catttgcata
    29041 ttcaagagaa gaagatacac cagcagatag attgccaaac catatagatg aagaagtaaa
    29101 aatacaaaga agagatactt taatgatgat tcaacaaaaa atatctgaag aacttaatga
    29161 caaaaagata ggaaaaactt atgaggtgtt aatagaagaa cagatagaag ataatgtata
    29221 tacaggaaga acacaaggtg atgcagagga aattgacagt atagtgtatg taaaaagtgt
    29281 agacaatctt gaagtaggag aatttgtaag tgttcaaata aatgatgcaa tggaatacga
    29341 tttaatggga gatgttttat atgaacttgc ctaacaagtt aactttgttt agaatatttt
    29401 taataccagt atttgtttta attatgttgc tcaatatacc aaataaattt ttaatagctt
    29461 gtattatttt tataatagct tcaattactg atgctttaga tggaaaaata gctagaaaat
    29521 acaatctagt cactgacttt ggaaaattta tggacccatt agcagataag ttattggtta
    29581 tttcagcact tacatgtatg atagaagacc atcttgtaag tagttggatg gtaattataa
    29641 tagtggctag agagcttaca gttagcatat taagagctat agctgctgct gatggaaaag
    29701 taattgctgc tggaaacagt ggaaaactta aaacgataac tcaaatggta tctatagtgt
    29761 ttttattgtt aggtgctcag tttgaaaatg tattgatatt aaatattggt gaaattctca
    29821 ttcttatagc tacactactt acattatatt ctggatggga atatctatat aaaaataaag
    29881 agctttttat gtcttctaag taaaaaatta tgctttaata aataaaaact aatgattaat
    29941 aaataaaaaa taacaactta aaattttaaa aatgtaaaaa agggtatact attatagtat
    30001 acctcttttc attttaagaa tattttcttt tgtgtatata attattaata atggtttata
    30061 aataaaatgt aatgaataaa aatataatca ttagtagcgt ttttaaattg actaggtttg
    30121 atttatgtta tataattaat atataacaag agaacaaatg tttgtagata aatgaaggga
    30181 tggtatagag atgagtgtag atcaagaaaa attaaaagcg ttgaatgaag ctttaggtaa
    30241 aattgaaaaa gattttggta aaggttcagt aatgaaattg ggagaagcaa catctatgtc
    30301 tatagatgtt atatcaacag gagcgattgg tttagacata gctattggta taggaggtct
    30361 acctagaggg agaatagttg aagtatatgg tccagaatct tctggtaaga ctactgttgc
    30421 gcttagttgt gtagcatcag ctcaaaaaga tggaggaata gctgcattta tagatgcaga
    30481 acatgcactt gacccagtat atgcaaaagc tttgggtgtg gatgttgata acctaataat
    30541 atctcaacca gatacaggtg aacaggcttt agagatagca gaggcattga taagaagtgg
    30601 agcgatagat ataatagtaa tagactcagt agcagcatta gttccaaagg ctgaaataga
    30661 tggagatatg ggtgattctc atgtaggttt acaagctaga cttatgtcac aagcacttag
    30721 aaagttaact ggttcaatta aaaaatcaaa ttgtgttgct atatttataa accagttaag
    30781 agagaaagta ggaataatgt ttggaaaccc agaaactact actggaggac gtgcactaaa
    30841 attctattca tcagttagat tggatgttag aaaaatagat acaataaaac aaggtgataa
    30901 agttataggt agtagaacta gagttaaagt tgttaaaaac aaagtagcac caccatttaa
    30961 gcaagctgaa tttgatataa tgtatggaga agggatttca aaaattggag accttttaga
    31021 tatagctgct gatgtagata tagttaaaaa atcaggttca tggtatagtt acaatgatac
    31081 taaacttgga caaggaagag aaaatgttaa aaaattcttg gaagataatt tagatttaac
    31141 tactgaaata gatgagaaag ttagagcatt ttacaattta aatgaagaac atgaagaatc
    31201 aggtacttca gtatcaaaag aaattgtaga agaataagta aaaatacaaa aaaataacta
    31261 gtaattaaag acatgccacg ctccctatta gcttgacaca atgttgaaaa aattataaaa
    31321 ttaagtgagg ataaaatatc taaatttaat tttaattatt aggaatattt tttaatcata
    31381 gtgatgacat tttgggatta ttaacgaagg aggtggatgt catagatagt gtagtaatga
    31441 ttgtaatagg tgcagctgtt ggtattatag ctggatattt tgttagaaaa aatatatctg
    31501 aagcaaaaat tggacaagct gaaaacttgg ccaaagaaat aatagataaa gcacaccacg
    31561 actcagaaac agtacaaaaa gaaaaattac tagaagctaa agaagagatc cataagtgga
    31621 gaacagaagc tgaaagagaa aacagagaaa gaagaacaga agtacaaaag tatgaaaaaa
    31681 gagtagtaca aaaagaagaa gtcttagata gaaaattaca aaatttagaa tctaaagaag
    31741 taaacctaag tgaaaaatta aaggtagtgg aaaagaaaga agaagaagtt gaagtaataa
    31801 aaactcaaca gttagaaaaa ttagaaagta tatcaggaat tacttctgat aaggccaaag
    31861 aaatcatctt aaccaatgcg gagagagatg taagacgtga aatgtctata atgataaaag
    31921 agatagaaag tcaagctaaa gaagaagctg ataagaaatc aagagaaatt ataggatatg
    31981 caattcaaaa atgtgcagca gatcacgtag ccgaaactac tgtaacagta gtaagcttgc
    32041 ctaatgatga aatgaaaggt agaataatag gtagggaagg tagaaatata aggactttag
    32101 aaaccttaac aggtatagac cttataatag atgacactcc agaagccgta attttatcag
    32161 gatttgatcc aataagaaga gaaattgcaa gaattgctct agaaaaatta atagcagatg
    32221 gaagaataca tccagctaga attgaagaaa tggttgaaaa ggcgagaaaa gaagttgaca
    32281 atattataaa agaatatggt gaacaagctg catttgaaac tagtgtacat gggattcatc
    32341 cggaattaat aagattatta ggtagactta actatagaac tagttatgga caaaatgtac
    32401 ttaaacattc tatagaagtt gctcatatag ctggtataat ggctgctgaa ataggagcag
    32461 atattagatt ggctaagagg gcaggtttat tacatgatat aggtaaggct gtagaccatg
    32521 aaatggaagg tacacatgtt gaaataggta tggatttact tagacgttat aaagagtcta
    32581 aagaagttat acatgccatg agtactcatc atggagatta cgagcctcaa acagtagagg
    32641 ctgtattagt tacagcagca gatgcaatat cagctgctag acctggtgcg agaagagaaa
    32701 ctttagaagc atatataaag agacttgaaa aattagaaga aatagctaat tcatatgaag
    32761 gtgtagaaaa atcatttgct atacaagctg gtagagaaat aagaataatg gtaaaaccag
    32821 aagctataaa tgatgaagaa atacatctat tggctagaga tatgactaag aaaatagagg
    32881 atgaacttga atatcctgga caaataaaag taagcataat aagagaaaca agagctatag
    32941 agtatgcgaa gtaaaagaaa taatatctaa ataataagaa aatattttta gaaatttaaa
    33001 tttgccacaa gatatgataa tatatcttgt ggcttttaaa ttgtttaagt ttaattttat
    33061 ataatgcaaa aataatctaa gtgctaaaag tgctacttac aaaagattaa taaaataaag
    33121 ctttatatat gtattattta tataattatc caagtttgtt tgatataatg aagttgtaaa
    33181 ataaatatat tactacttgg aatgcttgta cttaaataag atgaaaatac aatgacgcta
    33241 aagtgaggat tagagagagg gtacactatg aaaaaaaata cacttttaca tacaaatatt
    33301 atggtttgca ttattattac tcttggtttt gtggctacct ctataattgg atatcaatct
    33361 aataccaata tttttaaaaa tgatattgaa catgtatcta cattggctgc tgaaggtatt
    33421 tattatcaga tagataaact actttcagaa cctataaatg tatctcttac aatggcaaat
    33481 gacagtctat taaaaaattt tttagatggt gagaaagaac atttaaatga tgaagaattt
    33541 atttataaat tacaagatta tctgaatgtg tatagaaata aatattcata tgattctgtt
    33601 tttttagtat caactaaaac caataattat tatcatttta atggacttga tagaaatctt
    33661 agcgctaata actcagagaa tcaatggtat tatactttct taaagaatga tgatgaatac
    33721 tcattaaatg ttgataatga tgaagcaagt aacaatagta ttacagtctt tgtaaattgt
    33781 aagataaaag atgataatgg agcaactatg ggaattatag gtgttgggtt aaaggttaat
    33841 tcattacaaa tgttgcttaa aggatataat gacaaatttg atgttgttgc acgcttaatt
    33901 gatgataaag ggtttgtaca attagcagta gataaaaccg gtcatgagaa tataaatttt
    33961 tttgaaaatt ctagtagcga cttgtctaat tcgaaacaat taatattaaa caacaaaaag
    34021 gaacaaaaga gtttttggta ttcatctgaa aaatcaaaaa gttatattgt atgtcagtac
    34081 atacctagtt taaaatggca tcttgttcta gaaaatgatt ttactttaat gattaaacag
    34141 cttcatctgc aattttttaa aggcattgca gttatagttt taattataat atttgtactt
    34201 tttactatta cacatgtgct taaaaaatac aaaaaccaaa taataaagct tagtgtttca
    34261 cagaaattgg aatatcaaaa attgttgagc aaatctactg aaggtcttta tgaaaatatt
    34321 tttgaaattg atattactaa caataaagct ggttgtgaag atgagaatag gtattttcat
    34381 gaatttggat tagggcttaa taccccatat gatgaagcct tacatacaat agctaaaaac
    34441 caaatcaaag aagaatatgc acaaggttat ttagatacat ttttacctga aaatgtaatt
    34501 aaacgttata atagcggaat taataatatc agctatgatt ttttaattaa aaaagatgaa
    34561 gaaagttatc attggattag aattaatgca cgaattttct tttggacatc agatgaatct
    34621 gttcgtatga tatcttatcg taaaaatata gatgaagaaa aaaatagaga attactactt
    34681 ctcgaacgtt cacaacgtga ttctcttaca gggctttaca ataaagctac aacagaggaa
    34741 tttattcgtt catttttaaa aaatgaaagt aatcaagatt tagaacacgt ttttctaatt
    34801 ttcgatattg ataattttaa aaatgtaaat gataaatatg gtcatgtatt tggagacttt
    34861 gttataagtg aatttgcctt agaattaaaa tctcaatttc gtgaggacga tattgtggga
    34921 cgtattggtg gagatgagtt tgtagtatta ataaaagact ttaataataa taactatgtg
    34981 cttatagaca aattagagcg tttttgttct aagattaatc agaaaaaatt tgttgagcaa
    35041 gcagaatttt ctattgcatg tagtattggt gtagcaatgt atcctgaaca tggatatgta
    35101 tactctgaac tatatgagaa agcagaccaa gcactttact atgcaaaaag ccatgggaaa
    35161 aattcttatc atatattttc agaggattct attgatagta tttcatttca tatagactct
    35221 agagatataa aagtattatt agaaatggct actgatggtg ttgtcaaatt tgcttgtatg
    35281 gaaaacttaa aattacttta tttcaaccaa aaaatgcttg aatttactgg atattcagct
    35341 caaactgtta cttctatagg ttttgatatt ttttcgcctg tattacaaga cgacttacaa
    35401 atggtactag atacattaag agaagcaatt tctaaaagag agacttttga aatagttttt
    35461 cgtttttgtc atacagatgg tcatattttt cctgtaagga tgcaaggtaa gtttgtaagt
    35521 gaattatatc aaaatcgtta tcctgttttt tatgcgattt atacagacat atcaagtatc
    35581 aatactttac tagaaaataa atagtaaata ctacagtaaa atctaaaaat aggatataat
    35641 agtattaata taagaagatt ataaataaaa cctgctaatg aaaatagatt atttttagca
    35701 ggtttttaaa ttttttataa taaatcttat ttttggctaa caagatttat tttttttaag
    35761 actttactta ttattttaag cattaattat gaaatttatc attttattat ttacagaaag
    35821 tattttataa caataaatat ctatacttat tgcaaaattt ttttagcagt tttgtattta
    35881 tttgtattta ttttgaattt atttactaaa tttgcctata aaaagtatat ataaaaatat
    35941 agttcaaaat ggtataatta agtataacag aaggaggtaa tgtaagtgag ccaatacata
    36001 aatataaatt ctcagttaga cgccctaaaa ttgaaggagt tcgagaaaat attttacgaa
    36061 aatatcaatg aggacgttaa agtagtgcca aaagttactc cttttaaagg aataaatacc
    36121 gatttgttgt atgttaaaga tggaagaatt ttatttataa aatttatgga tacaacagaa
    36181 gatatatttt ttattttaga agaagagtta cttgaagtta tgaatgagga atatgaactt
    36241 ttgaaactaa aaatgggaca aaagaataga aatataagtt ataactacgt ttacattatg
    36301 ccatacgttg aagttgagga aacatatgaa tttgaagaat ttgttaataa taatataata
    36361 gataaaaata agcttcaaga tataatgaat aagggttcgc tggaggaata tcttaatgat
    36421 gagaatgatg aaataaactt aaatttattt ttactagaca tatgttcaga atactatata
    36481 ataaatgata aacttcatct aaatgaaaaa tttaaaaaaa tttcattcta caatgatgac
    36541 tataagtata cagcaactat gatggaagac gttcaaatta aagatgttgt ttctattaaa
    36601 tatgggaata cacttattga aggtggttct ggtataggca aaacagcaat tatgctttct
    36661 agggctataa aattagcaaa agtatatcca catcataaat tagtcatatt tacacataca
    36721 aaacaactgt gcaatgagct tcgagagagg atagagttat tatacaaaga taataacaat
    36781 ttagaagttc acacatttag ttcttttata tttaaactag ctaaaaaatt caatttaatt
    36841 gtagattata acatgttaaa aaatgattac gaaaagacct ttaataatct tgtaaaacaa
    36901 gcacagaaca ttataaaaaa taaaaatatg ttcaaggcta tttttattga tgaagcagaa
    36961 agctttttag agtatgaaat agattttata agggagtttt tatataaaac aaaattcata
    37021 tttaatgtgt gttcttgtaa ctccttgaat atctctaata gattgaatat atttaaaaaa
    37081 ttatataatg gtatagaatt tgatgataag attatcttaa gtaaaaatta tagacaagct
    37141 aaagagattg tagattttac aaataaattt tcaaataatt ctaactcata tatcaacgaa
    37201 ttaagaccaa atacagaatt tagtactttc ttttatacta aagcacttag aggtggaaat
    37261 aagtctgttg atataataaa agtaagtgac cttgatgacc aaataagttc tgtaatctgg
    37321 gaaattgagt atttaataag taaaaaaggt cttgattatt ctgaagttgc tatcgtttat
    37381 ccttacaata agaagaaatt aaaaagtgga aaaaccattt actttcaata tatgttaaaa
    37441 aaagcattgg aagaggcaaa aattccttat atatgtgcag aagataattt gacaaatata
    37501 agtaagaagg taggaactac aatagcaaat atatatgcaa taaagaattt agagtataaa
    37561 gcggtaatag tatgtgaatt agagatgtta tacaatcaaa ctataaatga tattgaacaa
    37621 gattatcaag taaatgactt tgtaggagat ttaaataagg tttatttagc tatgagtaga
    37681 gcaacagact acctaagtat agtaacaact tttaatgaag aagcaagtga tataataaga
    37741 cttattacag aatcaaaaga tatttagtaa aaaaatattt gtaatttaag aaaataaaaa
    37801 gagactgaga tttgtaaaat aaactttacc aattcagtct cttatttttt agtctacttt
    37861 cccaatatta tcaagaggta atagtctcac cataacctta ccaagaactt catcttcatc
    37921 aaccatacct acatcaggga atctactatc attactattt tctctattat ctcccattgc
    37981 aaatagttta ccttttggaa caacagtatc tatatctcca gaagtatagt tattgtgtat
    38041 atatggttca tttaataatt ttccatttac atacacttta gaatttgata tttttattct
    38101 gtcaccttca gtagctataa ctctttttat taagtctttt ttctttcctg tttctccatc
    38161 aactaaattg gttttaaaaa ctacaatatc gcctttttca ggtttaccaa ccttgtatga
    38221 tatcctattt aaaatcagat aatctttatc atctaaagta ggatacattg attctccact
    38281 tacaatagaa ggtcttataa attgtagaat tacaaatgca agtacaatag ccatagctat
    38341 tgacttaatc caatcaaata tttctttttt aacactcata acttttctcc ttatcatttg
    38401 ttattaaatt agaatacatt ataatagaaa gaaataagca agaaccacta tacccaagac
    38461 tattctataa taaccaaata ctttgaagtc atgttttttg atatagtcca taaaaaattt
    38521 aataactaca attgaaacaa caaatgctac tacagaacca acacctaaaa taagccattc
    38581 aaatccagta aatccaaatc cagcttttag aagttttaat gcactagctc caagcattgt
    38641 agggatggct aagaagaatg aaaactctgc tgctacatat ctagaagtac caagtaatac
    38701 tgcacctatt atagtagaac cagacctaga tgtacctggt ataagagcta gacactggaa
    38761 taatcctata caaagagcta atttatatgt aacttgagaa aaatctttat acttaggttt
    38821 tttatttctc ttttcaagcc ctatcattat tataccatat acaataagag caatagcaac
    38881 tactgttgaa ttaaagaata atctatctat atcatcttca aacagtattc caataactcc
    38941 agatggtata actgcaatta taaccttaag ccataaacgg actgtttctt ttttctgctt
    39001 aatattcttt gcgctatcaa aaggatttaa ttttctaaaa aatataacaa gtacagctaa
    39061 tattgaacca aattgaatta caactaaaaa tgtacttata aatgtatttg aaaaattcaa
    39121 ttttataaac tcatcaacta atatcatatg ccctgtacta cttactggta gccattctgt
    39181 tattccctga actatgccca aaatgactgc cttaaaaatt tcaagcaaac taaatgtttc
    39241 caaatcaaaa tacctccaat acaaatttat agtagcatat tttattcata gattaataaa
    39301 aaaatgccac cttttactaa cttataatac catagtactg tgtagtgcac aatggaagat
    39361 tgatattttc ataaaacctt cataatataa caaaataaac ttaaaagtta tctattgaat
    39421 aaggggtata tttgaggggg aaatatatgg tatagtaaaa gtatagctat tttattttat
    39481 gaaaaggaaa ggagttatta tgtatagtac aaaaatacta gatgattatg agtatgaaac
    39541 ttttaatgtt ttttctacaa aattaaatcc aaacacgaaa cacgattatt tatcaaaggt
    39601 tatactgttt aaagaatttt taaaagggaa agaattgatt tatgctacga aagaagattg
    39661 taaaaatttt gtagactata tacagactaa atatgcgaaa tcaacttgtg aaaagatata
    39721 tagttattta catagttttt ataacttctt aaaaaaagaa ggatacatag atataaatcc
    39781 atttagatat gtagaaaaac ccacagtaac aagaataaaa acaaaagatg atgttctaag
    39841 tatacaagaa ataaataaac ttataggtat cctaccaaaa ttaaatataa gagatagagt
    39901 aataatagtc tgtctagtta ctactgggtg tttattaaat gaattagtta gcttaaagtg
    39961 gaaagacctt atggtagatg aaaacgataa ctcatatgta aggttaggta agggaagaaa
    40021 agaaagagta gttaaattac atccatactt ttttaaactt ttagaagatt acaggaatta
    40081 ttctgggctt ccagaggtaa taatacctag tgatgatttt atttttacaa ctcaaaagag
    40141 taattctata acagatagaa atgtcagact tatagtcaaa aaagcattag atttagctgg
    40201 actttctcaa tattcagcaa gagattttag acattcattt gcagcaataa gtttaaggct
    40261 tggggcagat gaaagtgatg taaaaaatca gcttggatgg agtgataaat actatgcaat
    40321 tagatataag tatgtattaa attttgttga tagtgaaata gtggattact taattgaaaa
    40381 agataatttg gatataaata aaaaatagta ataaataaaa aatactatat ataaatgtga
    40441 acaaaaaata aaaaagtctt gttatagttc gtaaaattat atataattat ttatgtacta
    40501 atgtgtacac agtaatcaca cgacaaaaga tttaaggaag gtgctaatat aatgatagat
    40561 aataaatata ctacttactc aaacccactt acagacagat attgtagcaa ggacatgagt
    40621 tatatatttt ctccacaatt taaattctct acatggagaa ggttatgggt tgcacttgca
    40681 gaaggtgaac atgagttagg aatcaatata actgaagaac aattagatga gctaagagct
    40741 aatatagata atataaattt tgatgaagct agaaaaatag aaaaagaagt aagacatgat
    40801 gtaatgtctc acgtaaaagc ttatggttta caatgtgaaa aagccaaagg aataatacat
    40861 ttaggagcaa catctgcata tgttggagat aatacagatg ttatacaaat gaatgaagct
    40921 ttaaaacttc taagagtaaa gcttgtaaat ttaataaaca atttaaaaga atttgcactt
    40981 aagtacaaag atatgccagc tcttggattt acacacttcc aagctgctca acttacaaca
    41041 gtaggaaaaa gagcttgttt atgggctcaa gatttaattc ttgatttgga agatttaaac
    41101 tatagaatag acaacatgaa gttaagagga gttaaaggta ctactggtac tcaagcaagt
    41161 tttttaagct tatttgaagg agaccacgaa aaagtaaaag agttagataa gaaaatttgt
    41221 aaaaagatgg gataccattc ttcctatgca gtaagtggac agacatatac tagaaagtta
    41281 gattatcaag taataagcat actatcaggg atagctcaaa gtatgcataa gatgactaat
    41341 gatataagac ttttacaaag tttaaaagaa ttagaagagc catttgaaaa aaatcaaata
    41401 ggttcatcag caatggctta taagaggaat ccaatgagaa gtgagagaat agcatcttta
    41461 tctaagtata taatctctga atctataagc cctgcaatgg tacaagccac tcaatggtta
    41521 gagagaacat tagatgactc agccaataag agattggcaa tacctcaagc atttatggca
    41581 gcagatgcta tacttgaaat agggataaat gtaactgatg gtttagtagt atatgaaaat
    41641 atgataaata gacgtgtaaa tgaagaactt ccttttatgg ctacagaaac aatacttatg
    41701 gaagctgtaa aaagaggtgg agatagacag gaattgcatg aaataataag agaatattct
    41761 atgaaagctg cctatagagt aaagcatgaa ggcaaggata ataacttaat tgaacttata
    41821 atgaatgatg attcatttaa aatgagcaag gaagaaatac tatctataat ggacccaaaa
    41881 aactttatag gtagagctcc agaacaagtt gtagaatttg taaatgaagt tgtagaacct
    41941 gctataaaag attataagga agacttagga aaagtagatg tagacctaag agtatagaat
    42001 tgtacagata aaatataatt aaaaacggct atcttattta taaataagat agccatttta
    42061 atgggctagc gtcttctctc caccgctgtg aagagttctt ctttacttac tataccatga
    42121 atttaataaa atagctatat aaataatatt taataggaat aatataaata aaaataaaaa
    42181 aatgataaga ttactaatta aatttaaaca ttcagcaaaa actattgtac ttgcaatatt
    42241 tttaatgtaa actgaaataa agttatttag ataatttaat aaattttaaa acaaccgagg
    42301 tgattatatg aactatatag taaaagatac cataagtttt ttagtaaaaa catttcctaa
    42361 gatttattct agcctgtact tagaagacct aaaaaaattt gcaccagatt ataatgtaaa
    42421 taaaacacaa ttaagagcat tagttttcat aaaaaattat ggagtaataa gtatgactga
    42481 tttatgctct aagttaaata tagaaaaagg cagtttaact agtatggttg atgatttaac
    42541 tgataagaag tatgtaacaa ggaaaagaga tttagttgat agaagaaaat atctaattga
    42601 cattactgaa gagggagata agatagcaac tgattttatg gataaattaa gtgatggttt
    42661 aggagaaaaa ctttctaaat taactgaaga agacagaaaa aaatatttag aagcaataaa
    42721 tactcttcaa tatatattaa acaaagaaga atttagatag aaaaaatata aaaatttttg
    42781 tatttaatgg tactaagatt aattctttgt tattcattta actatataat tataagtcta
    42841 aatacaatct aaaaagtaca tcttaaattt tcttgatgta cttttttata atttctctaa
    42901 ctaaggcaag acaagtttta gatgctttaa ttaaagtgaa taaagattac tggccaacac
    42961 tatataaaga aaatgaaaaa tagtcaggtc taagtcttaa ttaatatatt aattaagaaa
    43021 tgtccccttt tcaaataata tctgaaaagg ggacatttta tatcattaaa tttatataaa
    43081 ttaagtttaa aaaattattt ttgtaaagct acatattgct ctaaaccttc ttttaataat
    43141 gtagcagctc tatgaaggtc tttttcattt aagatgtaag ctaatcttat ttcatcacgt
    43201 cctaaacctg gagtagcata gaatccttca gcagggcaaa ccataactgt ttcattatct
    43261 ttattaaatt cttttaacat ccaaattgtg aaatcttctg cattttcaac tggtaattta
    43321 gcaactatat agaaagcacc agttggtttt ttacatataa caccttcaac cttcattaat
    43381 tcattgtata atacatctct tctttttttg tactcttcat taacttcttt gaagtaagaa
    43441 acaggagttt tgtataactc aacagctcct atttgctcta atgtaggaac acaaagtctt
    43501 ccttgacata atttaagtat ttgagcgata agacctttat ttttgcaagc gatagaacca
    43561 attctagcac cacaagcact gtatctctta gaaacactgt ctattattat aactctatcc
    43621 tgtacaccct ctaagttacc acagcttgta tactcaagcc catcataaac aaattctcta
    43681 taaacttcgt ctgctattat ccataaatct ttttctttag ctatttcagc taggatatta
    43741 agttcttctt ttgtataaat tgcaccagtt ggatttcctg ggttagaaag aattatagcc
    43801 ttagttttat catctacttt agacaatatt tcttctttag atggaaggtg gaaaccgttt
    43861 tctgcctttg ttgtaacagc attaacttct acgtttacag attgaccaaa tccattgtag
    43921 tttgtataga atggttctgg aactaataga ttatctcctg ggtcacaaac tgccatcata
    43981 gtgaaaagta aagcttcact accaccgtta gttactaata attcatcttt ttcaaaattc
    44041 atatcgtaag ttttatagta attttgaagt gcttctaata attctggaat accttctgat
    44101 gtagcatatt ctaagacttc gctatcaaag tttttaacag catcaaaaaa tcctttagga
    44161 gtttttatgt ctggttgtcc tatgtttaag tgatatactt tgattccttt atcttttgct
    44221 gcttgtgcaa atggaacaag ttttctgatt ggagaggctt gcattgcact aactctgttt
    44281 gaataattca ttttaatacc ccctatttaa tttaaatacg tatattgtat tatgtaaatt
    44341 gtatgtttga atacaagaca tctttacaag ataataataa catacttatg ggtaaaaatc
    44401 atcaaaaaaa attaatatag ctttaaaata aacttttaac aaattatagt aaaataccca
    44461 tgtttatgcc actaaattat gtattcataa attaatttat agtaagataa tattctgatg
    44521 tactgatagt gattttttag ttataatctt tcagctatag acaaaatata taataataaa
    44581 tatgcaaaat tataaaaaat attataaatt tatttaacag atacgataaa tatcatataa
    44641 ttatattaaa ggctattaac taagaggtgt taattatgaa agaattaaga atagatccaa
    44701 ttaccaatga tgttgttata tttgctacag ataggttaaa aagaccttta gatacagcag
    44761 atatcccaaa tgaagatgaa gaaactaatg aatatgatga agaatgccca ttttgcaaag
    44821 gaaatgaagc tcatgcaact gatgcattat ttgaaataga tagtgaagaa ggatggcttg
    44881 taaaatctgt ctacaataaa tttcctataa ttgatgatat ggcaagagat gtatatggtg
    44941 ttcatgaagt aatgatagag agcgataaac ataatcgtag tttttataac atgagtcaaa
    45001 aagaatttga agatgttttt tttatgtata gaaatagatt tagagatttg tcgaaagatg
    45061 ataaagtaga gtatgttagt atcttcaaaa acttcttgag aaaggcagga gcatctttga
    45121 tgcatccaca tgctcaaata ttgtctatgt cttttattcc acctgaaatt acgaatgaac
    45181 tgttggtttc aaaggagtat tatgacagca ataaaagctc tttgtatgat gatttaatag
    45241 aaaatgaaat aagtttagat agaagagttg tttataatgg agaagctttt ttggtactta
    45301 taccatatgc aaccaagtat agtggagaag taagaataat atttaaagat aaaatagagt
    45361 ttggtgagtt aaatgataat aatatacagg agctttctac aatatttgaa aagttgttta
    45421 agaagttata caatatcaat ggatatatgc catttaattt atgtattcac actcatccaa
    45481 caaagattga aacaaaatcg tattttaatg ttcatatgca cataatccca agaaaatata
    45541 attttggagg atttgaactt ggaacaaata tgtatgtttc ttcaatgagc cctgaagatt
    45601 taacaaaaaa gttaaaaatt gattaaaaca tatattttta ggtattaagt aaatagtaat
    45661 tttagatgaa attatagtat agcattgtta aaataaaagt aaattaagaa tttacaataa
    45721 aattgttgaa aagcccccat ctttagctat ggggagtgtg tcaatgttta gatgaggagt
    45781 ataagtatga aatttatatc atggaatgtt aatggaataa gagcttgtgt tgggaaagga
    45841 tttttagact ttttcaaaga agtagatgca gatatatttt gtttacaaga aactaaattg
    45901 caagaagggc aaatagagtt agatttacca ggatattttc aatattggaa ttatgctgag
    45961 agaaagggtt attcaggtac tgctatattt acaaaaaaag agcctttaaa agtaatgtat
    46021 ggaataaata tagaagaaca tgacaaagag ggtagagtga taactctaga gtttgaagat
    46081 ttttactttg ttacagtata tacgccaaat tctcaatctg aattaaagag actagaatat
    46141 agaactagat gggaagacga ctttatagat tatttaacca aactagataa tcataagcct
    46201 gtaattgtgt gtggagatat gaacgttgca cataaagaaa tagatttaaa aaatcctaaa
    46261 aataatatga aaaatgcagg ttttactaaa gaagaaagag agaagttttc taaattatta
    46321 gacagtgggt ttatagacac atatagatat tttaatcctg ataaagaagg tgtttatagt
    46381 tggtggtcgt atagatttaa tgcaagaaaa aataatgcag ggtggagaat agattatttt
    46441 tgtgcatcca aaaaattaga agatagatta gtaagtgcgg atatacacac tgaaatatta
    46501 ggttcagacc attgtccagt tgaattagag ataaaataaa aattaattat gataaaaatt
    46561 gggctgtaga tataaattta aagttaacta gttttttaat ctacatgcct attttttatc
    46621 taaataaact ctatttgttt tttctttgct taacattttc taatgtaaat tgatttgttt
    46681 tccacatatt ataagctaag ttaatgattt ttttctcgtc tttagttaat tcacgattta
    46741 aaattttcct aaattcatca aataacttat cataatcaac tctttttttg ttagaatatc
    46801 ttatagtttt aggttttata ctcgtataaa gatatatatc tgggactata cttggattgt
    46861 atatcttaat aaaaacttta gcagtataat atgcatcatt taaagcattg tgataagaca
    46921 ttttttcatc aagttccaat atagaaatag cattttgtag gccaatgctt tttcctgctg
    46981 gattattgaa atatttagat gcatgttgtt gtatattaat ataagattta ggtaaggaat
    47041 ttgatggtag cttgtgatag ttgatattcc tgtataattc cttcaaatct ccagctcccc
    47101 aaacacataa tatagggtct tgtgatgata taaattttat aaaattgttg tagacctcag
    47161 ggaaagtagg cgaatcatta aaatcagaac ttttaatatt agtcatacga ctaataaagg
    47221 gatgtatgtc tttataaatt gtaggtttta catagctatt aaacgtatct attatattga
    47281 atttagaatc caatttaatt gctcctattt gtataatttc aaaaggacac ttttcattgg
    47341 atacagtttt attgagtttt ttatcaaatc cttggttaaa ttccaaatcg aaaattatgt
    47401 attccataaa gtttatctcc taaatttttt tattatttct tttactatag attatattat
    47461 aaataaaatt aaattttcaa ataaaaatac ttttatttta gtatacccca tatttgtaaa
    47521 aatgttaaac tattgtatgt ataatatttt ttccaataaa aaatattgcg aactttttat
    47581 acttgatata taataatata aataaaaaca cgaataaaac acgaataatt tgcaagaaaa
    47641 attcataaat gtaaggaaaa tgaaatttat cttgtattta acaaaataaa atatacataa
    47701 aaattatggg agagtggaaa aatggatagt ctattatacg taatagagaa agataaacac
    47761 actaatgaag aattaagaga aatcctaaaa agcaataaaa atataagatt tgtttcctta
    47821 atgggggttg atttaggagg aaatgcaaca gatgaaaaga ttcctgtaga attatttttg
    47881 gaggatatag ataaattttt ggaatcagct atacagactg atggttcaag tgttgagctt
    47941 tataatatag ctacattaaa taatgcgaaa gtagatttaa tgccagataa aagttgtcat
    48001 tggtatgtag attacaatat ggaatatata gacgaagaag taggtctacc tgttggaaca
    48061 ttaaagatac ctgcattttt aatacatgat aataaaaaag tatgttctag aggagtactt
    48121 caaaaagcag ataagtactt taaaaagtca atgtatgaaa tatttagaga atatccacat
    48181 gtaataaata acataggaat agattcagta gatgatatag aggaaataat gttaacagca
    48241 gctacagaac ttgagttctg ggttaatact cctgaggata aagctgactt agagaaatta
    48301 tatgtatcac aaagcctaaa agagcaatac tggaaaagaa ctcatggtat tataagaact
    48361 tgtttagaga aaagtttaat tatacttcaa aagctaggtg taaaccctga aatggctcac
    48421 aaagaggtcg gaggaataca aagttctatt agtatagatg gaagaacaaa ccatgctatg
    48481 gagcaattag aggtttcttg gaagttttct acaccgttac aagcagcaga caatgaatta
    48541 ttagtaagag atgttataga ggatgtattt acatcacatg gactagaagt tacatttaaa
    48601 gcaaaaccaa ttcatggagt agcaggaagt ggtggacata cacatgtagg agtaagtgcg
    48661 aagttaaagg atggaagtat aaaaaatcta tttgcgccaa aagatttaaa agaagattat
    48721 ctaagtgaac taggatatgg ggctcttatg ggacttcttt acaattatga agtattaaac
    48781 ccaattgtaa cagcttctaa tgatggattt aatagattag ttcctggatt tgaagctcct
    48841 gtatgcatag ttacatcttt aggtcatagt tatgagattc catcaagaaa taggtcagtg
    48901 cttgttggat taataagaga tatgaaaaat ccaaagactg taagatttga gttaaggtca
    48961 ccaagccctc tatctaacac gtatttagta atagcaggat gttatcaaac aatgttggat
    49021 ggtataaaag cagcagctaa gagtggtctt agtacaaaag aacttgaaaa agagttatct
    49081 aaaaatgtag gtgaagaaag tttctattta gaaaaagata gagcatatag agatgaaaat
    49141 gatgtatttg aacattatag tttggaagaa agaaatgcaa gatttggaat accaccggct
    49201 acagtttatg aaaatatgaa aaacttagaa atatatgctt caaaattaaa atctttaaaa
    49261 caaggtgatg tatttactga tagtataata gaatcattta agattggagc tatagataag
    49321 tggcaaaaga aattaaaaac tagaataata gaggctggga ttcaaaaaat aagaagtatt
    49381 gtcaagatac acacaaaaga aaatatggat gcgcttgatg aggtagtttg gaactcaata
    49441 tcggatttaa agttcaatat tatgaaggat actttaacta gagaatcact attcactaga
    49501 gtgagagaag ctatagaaaa taaggattac cagactgctt cagatttaca aatagaatta
    49561 aagagaagta tggaagaaat acaacaactg tatatgcagt acaagaaaaa tatatactaa
    49621 tataacaatt tgattttgat atgataaagg caatcaagta ttattaaaca ctatgagtaa
    49681 attctcaagt gtaaaagcat acttgattgc ctttaatttt atgtttgaaa ttttttaata
    49741 gtacaattta actgtaatga ttatctatta attctgatat ataatcagca attttctctg
    49801 gatgaatgac tgttttaaat tcttttaaat tttttttcat aaagtttatt atagaatcaa
    49861 attcatttga tactaattta taaaatatgt ttttaaggtc taggtcatca ctataaatca
    49921 tgccaagacc cttatctatt ataaatttag cgttttcaat ttcttgtcca acttttggca
    49981 tttttacgag tactggagtt tgtgattgaa tagcttcaaa tatagttgct cctccaggct
    50041 tagttagcat taggtcacat tctcttatta gattatacat gtcgtttaca aatccaagta
    50101 ctttaatatt ttttagaggt tttttatgag ttagattgtc atataatttt ttgtttttac
    50161 cagtaactat tgtaatttct atagaattac tatgttcttc aataaattca tctatccaat
    50221 gcataaaatc ctcatctata tcaaatagac ctcttcctcc acctagaagt aatagtctat
    50281 atttatcaca acatagttct ttactttcaa tttgaaatct cttatcaaca ggaactccag
    50341 taacctttat ggagtctgga tttattcctt tctgaaaaaa tctatttttt atttcaggag
    50401 aaggaacaaa atacaaatct gtattttcaa aaacccattc catactatct acaacatctg
    50461 ttataactgt aagtgtaggt atatttatat caggattttt tatcttaaag ttatttacac
    50521 aagcagcagc tagtggaaat gtagagataa tcaaatctgg atttatatca gcaatatact
    50581 cagaaagttt aggtgtatat aatttatgag ataaatcatg tcttgaatca aacgatttct
    50641 taaagtaata atagtaatta tataatccag gagtatattt tgtattgttt tcataaagtt
    50701 ttaccatagg cttattcatc atgggaatac ttgcatttat aaagttttgt ataacaacat
    50761 tatagttact atatttttca ataatacatt ctttgactgc ttttgcagca cttatatgtc
    50821 cagcaccaaa ttgagcagtt aggattaata ttgttttatc atctttcatt ttagccaatt
    50881 tatcaccact ttcataaaat atatctgatt agagtattat acatttatag aaggatttaa
    50941 tcaacaagaa tatttaaaaa taactattgt gcagaacata gtactgtgtt attatgagga
    51001 tataagaagt tttaacatag taccttgtaa aacacaatac tgtgtattta aagaaaggat
    51061 ggagtatatg aacacacaat ttagaaaggg tgttttagaa atttgtgtac ttgctctcat
    51121 atctaagaaa gatatgtatg gatatgagat agtacataac atctctaaag taatagatgt
    51181 aaatgaagga acaatatatc ctattctaag aagacttaca aaagatttgt atttcgaaac
    51241 atatatacta gaatctaatg aaggtcctgc tagaaaatac tatagaataa cttcactagg
    51301 aaaagagaat ttatccaatc tgatggaaga gtggagagaa tttgtaaagg ctgttgagat
    51361 tttaataagt gaagatgagg gaggtaatga acttgaataa aactgagttt cttgaaattt
    51421 taaaggatta tctaaaaaaa gatttttctg agagcgaagt taatgatata ttgagagatt
    51481 atgaagagta tttcgtagat ggtcttatag agggaaagag tgatatggag ataatagcat
    51541 cacttggctc accaaaatct atagcaaaag aacttatctt acaaactaaa gaaaaaaata
    51601 ttgaagagga aaaaataata aatacagatg ttttgaatga taagtttagt aaatttaaat
    51661 cagatatgaa aaaaggttac tctatcttaa aagatgaagc aaaagaaaag tatagtaaat
    51721 caaaagaaaa tatagatgga aaaataatga atacagacat attaaatggt aaatttagta
    51781 gatttaaatc aaatgtaaaa aaggattatt ctatcttgaa agatgaagct aaggaaaagt
    51841 acaataaatc aaaagaaaat ataaatgata aacttacacc aagtatagaa gaaggtgtag
    51901 gaggattatc cagacaagtt ataaaggggt tattagtagt gttatcttta tttctaattg
    51961 ttccagcatt tgcgtttgta tgtgctattg tatctgctac tattgcatta gtatgctcat
    52021 taattgcttt tgttatatta attccatttg tgattaaatt tatagcaatg gttccagatg
    52081 ttatgatgtt ttgtattttc gcaaccatag catttgtagg gcttgagata cttgcatggc
    52141 aaattttatt atttgccata aaactaggta aacaattact aaataattat atacattgga
    52201 taaagagaaa aaatatttat ataaaggcaa atgaaaagat ggaaaaaaga aaaaaagcta
    52261 ctttaaatga tgaagatttg aataaagaca ttaatgaaaa ttcatataat aatgattact
    52321 acaatagaga agaagaaagc ataaaagaaa ctgatgaata taatgatgat agtataaatt
    52381 ttgaggcgat atataaggac cttgaagata tagaaaataa gaaaggagaa gataaacatg
    52441 aataaaaaac ttgctatatt tgctgcagtt ttattggtaa taggtataat agggacaaca
    52501 tggtcaggga ttttagttat gccaagccta ataaactttg gtttagaaaa ggaagctgaa
    52561 ttaaacaaag aaaacaaact ttatcaagaa aaagtaaata ttgacaagtt agatatagct
    52621 gttgacaata taaatgttat gataagaaaa agttcaaatg aagatgtgcg tgtgacaaca
    52681 agagggaata atgaatttta caaatacagt gtaaccctac aagataagac tttagttgta
    52741 aaaggcgaaa gaaaatctga aaataaaatt aaaaagatta gaagtttcga ccacttatta
    52801 aatacatcta taaatagtat gttttcacgt gattatagag aaattagaat atatgtacca
    52861 aataatgtag atataaatgc atcaagtata agttcgtact tatttatatc tgatgatgta
    52921 gattcaaata atataacata taaaacttct tctggaggtt ttagcagagc tataacagaa
    52981 aataaagtaa atagattaga aaacttaaac ttaatatcta atagcaatct tcatctatca
    53041 acaaagtcaa ttttaggcgt taaaaatgta aacatagaat cagagtcatt ggatatatct
    53101 tcagagaatg gagatgtatt tatcaataat atagaagagt atatacctga aaatgtaaat
    53161 ataaaagaga aaataggtag aaattcaaat tatgaaagtg aattttactt gtactctgat
    53221 atgccaattg ctaagttcct ggacatagaa gttccaaatt ctaaggtaag acttgatata
    53281 ccagtaaata agtataaatt taattgtgat ataaagtcaa aagaagcaat tgaagaattt
    53341 aataatgatg aagaatatga caatgattca tatgattatg aacataatga agaacatagc
    53401 aacaagtata gaaatacgag ggaaataaaa gggcttttga ataaaaatct gtcgaattta
    53461 gagaaagaat atactataaa aataaattca aatagcttag aattgtaaat aatttactat
    53521 aataatttat aaattgattt aaaagtataa aaatataatc tatactatgg tataataagt
    53581 atcgaaagag aattaggaga gggatactta tgaataaaat agcagtaagt tttttaataa
    53641 ttgctactac tttattgagt acggcatgta tggattatag catcagtgca gttgagctag
    53701 ttgattctaa agaatcagca gttgtaaaga aggatgaaga tgcaaaagaa gaaacaacta
    53761 gtaaaatgat taattctaaa aaaactacta aaatacctat agagataatt tcaaaggatg
    53821 agaaaatagt aaagtactta cagattgatg aagaaagttc acttaaggat aaactgcgat
    53881 taatcttaga tacattatca aatgagtatt ttaatggttt agacatggaa gtagaagtta
    53941 aggaaaaaga taatcttgtt aaaataaact tgatagaacc agataaaaaa agtagagttt
    54001 cttggaaaga tgattatttg aatgaacaaa atataatata tactataaat aatattatta
    54061 aaaatgtcat ccaagaagaa gataatagca tttggattga agaagtagag atatactaca
    54121 atggaaaatt aatagaatta agataaaaaa agatgtgttt ttaacacatc tttttttgtt
    54181 ttttaattct tataaaatcc ttatatttat gatttagaat gattcttgta aataagtttg
    54241 acaaaagaaa ggatgaaaat tatgagtaat tatattttgc aggtaaaagg agtttctaaa
    54301 aaatttaagg agcagatggc agttgataac atttcactag caattaaatc taattctata
    54361 tatggattat taggaccaaa tggagctggg aaatctactt tattaaaaat gataactggg
    54421 attttaaatc caacttcagg aaaaataatg tttgagggac atagatggac tagaaaggat
    54481 ttatcaaata ttggttctct tattgagtct cctgctatat atgagaattt aacagcacga
    54541 gaaaatttaa aagtccatac tactttactt ggtcttcctg actctcgcat tgaagaagtt
    54601 ttagagactg tagatttaag agataccttt aaaaagcgtt caggtcaatt ctctctaggc
    54661 atgaagcaac gccttggtat tgctattgca ttattaaatc acccaaaact tttaatctta
    54721 gatgagccta caaatggtct tgaccctatt ggtattgaag aacttagaga attgattcgt
    54781 tcttttccaa aacaaggaat tacagttatt ttatcaagcc atatcttgtc tgaagttgaa
    54841 caagttgtag atgaaatagg aataatttct aatggagtaa tgggttatca aggagaagta
    54901 tcaaaagaac aaaacttaga agaacttttt atgaaagttg tagctgaaaa tagaaagaga
    54961 gggcagtaat atggaaagat ttattagagt ggaatttcaa aagatgaaag gaacttttgg
    55021 aatgaagttg atatggatag ttccagtgtt ttgtatactt ttgtgtggac taggtggagg
    55081 gcaaaatgct gctttcaact ggtggtatac gacatttctt ccaggagcat taacattaat
    55141 atcttcttta atagtattaa aagatgaaaa aagtaaatat cgtggtattt taccattgcc
    55201 aattgaaatg aaagacgttt ggactggaaa aatgatttac tgtattattt gttgttttat
    55261 agcatcaatt atttctgcaa taggtgtagt ttttgttggg ataatctata aagaaactat
    55321 ttcaataggt caaaatatca ttgcaagtat attaattatt ttactattta tgtggcagat
    55381 tcctctttgt atgtttttag cttcaaaatt tggtatgttt gttacagttc taacaaatat
    55441 gttctttact attgttggag ttgctgtttt ctcaactaca gaaatgtggt atatgtttcc
    55501 atattcgatt ccttcaagat taatggctgt tgtattgcat attctgccaa atggtcttcc
    55561 tgtaccagag ggaagtgaat ttttaaataa tgctgttatt ttgccaggag tattaatatc
    55621 tattgtttta tttgtattat ttgctttagc tacaagggtt tggttcaata atagagaggt
    55681 gaagtaatat gagacagtta ataagaatat tttgttctga tttaataaaa ttaaagagaa
    55741 attttataat actaatgcac atttgcattg ctttaatggg gatgggattg tttttatggt
    55801 attataaggt ttcaggagct gataatatac taaagatagt agcatattta caagttatag
    55861 caatagcttt tcctttattg tcaagtgttg tgtgttcaat gtttgttgaa caagaatatt
    55921 atgcagggaa ttataaacat atgttaacaa catctaatcc aaaatatctt actcttataa
    55981 gtaaatatat aatcttagta tgtcttggtt ttgtagcaac attagtgtct gtattaggtt
    56041 ttaaatttgg tatatctaag gcttacttta catcaagctt ttatatgatt tcaattctaa
    56101 ttttaattgg gtgtaattta tttgaataca tattacattt attcttaagt ttaaggttcg
    56161 gaaaaggaac atcaattgga gtaggtatag ttgaaatgtt actttcagca ttattattaa
    56221 ctggattggg ttctggtatt tggcagtatt ttccttgtgc atggggtgtt agatttataa
    56281 ctatttggtc gtctttttca agttctaaaa cggttgaata tataaaggtt gaatcaataa
    56341 aagcatatca atcaacaggt ttaatttgtg gttttgtaac aattttagca tttgtaattt
    56401 tatgtatttg gttttctaaa tgggaaggta aaaaatcaga agaatagagt aaaaattgac
    56461 tgtttattta tattattatg ttaaaatata acttagcaat aaaaagatat aaaataatca
    56521 aataaaaaac tggttgggta ttaattatga attaattaaa ctattggagg acagggtaca
    56581 aatgcttgga ggtaaaaaat ctaacaacaa aaaagttgaa aagttaagaa ctatttttat
    56641 aaaatattta tctttattct ttattatgac aatttcaatt gtactccttt taatgttatc
    56701 attttctgta ttattatcat caggtgtaat tttaccagct aattatgcag aaaaacaatt
    56761 taataaatat aaagaacaga ttatttcaag tgaaaaagta actgaagata taattccaag
    56821 tatatatgag tatggggttt atactttgga tgggaattta atttcaggga cctttaataa
    56881 aaaagaatca aaagaagtat ggaatttaat gagagatatt gaagaaaggc atgcatattc
    56941 agaaagttat ataaagtttt ttaagaaaga tgaagttttt ataataaaat acaaaatagt
    57001 atcagagtat agttctccaa ttttaagagc atatttacca aaaccagaga cattgggtat
    57061 gattattttt agtataatat tttttattga aattgttata ttatcaaaag tatttggcaa
    57121 gaaatttaat attgaaatgg agcttttaaa aaatactaca gaaaaaatag aacaacagga
    57181 tttagatttt gttgtagaat ctagtaaaat ttatgaaatt aataatgtcc ttttttctat
    57241 ggataaaatg aagttggcgt taaaagattc tttagaaaaa caatggatgc tagaagaaaa
    57301 tagaaaggaa cagatatctg cactggcaca tgatataaaa acaccactaa caattataca
    57361 tggaaatact gacttattaa ttgaaataaa tgaaaatcct gagttattag aatacatgga
    57421 atatatctca aagggtgtca ctcaaataga aaaatatatt aatactttaa tagatatatc
    57481 aaaaacagag aatggctata tattaaataa agaagcaatc agtatgagtg agtttataaa
    57541 agatgtttta gtgcaaatag aagcattagc tagtactaaa aacttagatg tggagtttta
    57601 taaacaagat aatttgccta aaaatataac tatagataga gaactgttat tcagagctat
    57661 tatgaatata atttcaaatg ctatagatta ttcaccaagc cagagtaaac tatacataag
    57721 tgtatcagta cataataaat acttaaaatt tgtagttaca gattgtggaa gtggtttttc
    57781 taaagcagat ttgtcaaaag ctacagaaca gttttataca ggagatttga gtagaaattc
    57841 taaatctcat tatggaatgg gactctatat tgtaaataat attgtacaaa aacataatgg
    57901 gactttatgt attgaaaatt ctgtgaaaac tggtggtgct atggtaacaa ttgaaatacc
    57961 aatagtttag taaataatat ccattttgta aatacctaaa ttttatgatt tataggtatt
    58021 tataaaatgg atagtttttt tgattttata tattggttaa atctgataaa aagttttcaa
    58081 acataactcc atcatttcta tcagtatcaa attgagatgt gtaatttata gttttatata
    58141 taaaatctgt tgcagtatta accgctactc ccaaatcatg tttatttact aacataccac
    58201 aaagtataga tgtgaatata tctccagttc cactgtaaga acaattatta tatttgactg
    58261 atgtaaagaa tacatggtca ttatctctat tgtaagccaa atttaatata ttatcatctt
    58321 ctaatatacc agtaataacg actttgctag gtcccaaatc agatacagat tttgcaatat
    58381 atataagctc atctctatta taatcgcttt tggtataatc atttccagtt aagaaacaag
    58441 cttctgttaa attaggagta gttaaatctg aatgtttaac taattcttta atttcctgtc
    58501 tcatttcttc tgtgaatatt ggatacataa ctccattatc acccatcaca gggtcaacta
    58561 cgataaaagc attgggataa tcgtttataa aattagccac tatctcaatt tgatgctttg
    58621 aacccaaaaa accactatat atactatcaa aattgacttt taaatttttc caaacatttg
    58681 aatattttac catttcatca gtaaagtcta agaaagtaaa ttcaggataa ccagtttgac
    58741 ttgaaagtat ggccgttgga aatggacaac attgaacctt taatgctgaa agtataggta
    58801 tagcaaccga taatgagcat tttcctattc cagataagtc attaattgct gcgacttttt
    58861 tttgcataaa aaaccctcca ttagtatgta ttaattataa tgataccaaa atatttatat
    58921 acatatatat tactataaaa aaaagaaaaa agtagattat aaaataaaaa attgtaaaaa
    58981 aaacagtgta ttgatacaat taatttttaa tattggacat aataaaatag agaattatta
    59041 aatatgaaaa ttactatatg tgacagaata ttctttgtaa tttgatttgt aaggtgtact
    59101 atttgggagg tgtagctttg aaaatactga aaaataagaa taagtacatc aaaggtataa
    59161 tggcatttgt atttttgtct ttagctacta cagcaggtgt atttttaatc aatgatttaa
    59221 gtatgaaaaa tatggaagaa aaagtcatgg aatctgcaaa tgttgaaggt gatgatgtaa
    59281 aagaccaata taaactattg cttgaaaact tatttgacta cagaaataag gcaatattag
    59341 agaaaaatga aaatatttta aaaggtcttt atgaaacgga taaaaaattt ggtctgtggg
    59401 cttatgaaaa tgaagtaaaa aagatgaaat atttagaaaa ctggtctagt aaacaaggtg
    59461 taaaatttaa agacataaag acaagggtta agattaaaaa aataaaggaa aaagaaaaag
    59521 acctctatgg tataatctgt tcagtatcca ctgaatataa gtattcatat gaaaatcaaa
    59581 aggacaaaga aaatgccttt agaataggta catatcatta tctaaatgta aaaattatag
    59641 ataatcaata tgtcataact aaagagtggt atacagaccc ttttgcagac tctttaaatt
    59701 tagaaaatat aaaatctgat gatataagaa attatattgg tcaacaagat ggtgtagagt
    59761 tacagcttac agatgaacaa aaaaaagcta tagattatgc acataaatac tgtggagccg
    59821 cagctgatga agaacatggt atgaaattta atccaaacta tagggattat aatccagaag
    59881 gtggagattg tgcaaacttt gcatcacaga taatgtttga aagtggaagg ttcaaaaaga
    59941 actcaatttg gaattatagc gagagagcag gtacaaaagc atgggtaaat gcacaagctt
    60001 ttaaaaatta tgcactgtat agtggaagag gttcattaat tgctaaaggt tcctatgaag
    60061 aagtatacaa agaagcttat aatttacgtc caggggattt tgttggttat gagaagaaag
    60121 gcagaataac acatgtttcg acagtgacag gattagactc aagaggatat cctttggtaa
    60181 cttgccataa tactgataga atgttggtgc catgggattt aggctggagt gataagtcca
    60241 taagattcca tataataaaa ataaattatt aaaaaattat aaagaaaaat aaagtgtaaa
    60301 agataataat catttaaaat tataaagtaa aaaaattgat tattaatgta taaaaataat
    60361 aataattgac aaacatagct atatatgata gagtagtaat aaggttacag aaaagagtag
    60421 ctaaatattt gtgttttttt aggaggattt attaatgaaa actggtgtag ttaaatggtt
    60481 taacaacgaa aaaggatttg gattcatatc tgtagaaggt gaaggagatg ttttcgtaca
    60541 tttctcagct ataactggag atggatacaa aacattagaa gaaggacaaa gcgttgagtt
    60601 cgaagtagta gatggagcta aaggtcctca agctgctaac gtagttagat tataattaaa
    60661 aattcatata tattagtgtt ctagtaatat gagagataag ccgctaatca tttagcggtt
    60721 ttttcagttt ttgtaaataa aattaatagc aaaataaatt aaaattatta aaataaaatc
    60781 attaataatg agataaatat gttaaaatta atagtgtaga gtaaaattat tatggctaag
    60841 tttaagtcaa ttaattttta gtaaattttc taaaaagaga ataagtgata cttatagacc
    60901 atataaaaat attaataaag cataataaga ttaaaatgag caaaggaaaa acgcttgtta
    60961 cagcgtatag tattaagaat acttagaaaa taagaaagga gaaagttact gcaaaaaagt
    61021 aacattataa atattgagta atatttataa gttttcagta acggtgggta gtgtaatgaa
    61081 catattattc tttctaacac caaaaagtga agtagcatat atatatgaag actacactat
    61141 aaggcaagcc ctagaaaaaa tggaatatca caaatactct gcaattccaa taataagtaa
    61201 ggatggtaaa tatgttggaa ctataacaga aggtgatttt ttatggacat taaaaaatga
    61261 tttaaatctg gacttaaagg gattggaaga tgttccagtg acagatataa atagaaaaat
    61321 ggataattct cctgtttcca tcaacgcaga tattgaagat ttagttataa aatctttaaa
    61381 tcaaaatttc attcctgtta tagatgacca agacacattt attgggataa taaaaagaag
    61441 agatgtaata ggttactgtt atgagataat acgtggatat aaaaatttag ctaatgataa
    61501 ttaaaaatct tatttaaact tttaagctga gttctttaca ataaaaaaat gataatatga
    61561 aactgaatat ttaaacttta atataaaaag ctgtcttttc taataaatat tgtgaaaaga
    61621 cagctttttt atatatgacc ttatgattaa tcgttgtatt ttacaaggtt tccgtactta
    61681 gcattaagag catttatctt atttccataa acttcatttt gtttttgata taataaactt
    61741 ttttcaactt cagccttaac ttcatcaaat gtagactctg tactttcttg aaggtcttct
    61801 aattttatta tatggtatcc aaattgagtt ttaactggtt cacttacttc acctttagcc
    61861 atagagaaca cagcttcttc aaattcagga accatttgtc ctctaccgaa tgttcctaaa
    61921 tcaccaccca tatctttaga tgggcaagaa gaatgtttaa gagctgcatc ttcaaaagat
    61981 atttcttctg attttatttg agcaagtatt tctttagctt tttcatcact atctactaat
    62041 atatgtttag cagttgcact ttctggttta gagaaagagc tcttattagc ttcaaagaat
    62101 tttacttttt catcttctgt tacattaaca ctagataaaa ctttatttat agcaaattgc
    62161 tttaatacat tttcttctat ctttttcatt tctaatttaa atatttcttc ttcatctaat
    62221 ttttcttctt tagcatctaa gaagaataat tcttgattca ctaaatcatt taataagtgt
    62281 ttttttcctt cttcagtttt aaattgcata gcttgataag ggtctaatga ttttaatgca
    62341 ttttcaatat caatattagt tatctctttt tctccaactg ttgctaaaac ttttttttcc
    62401 ataatagtta actccttcat agtgtatttc attattaata taagactacc atcttaaata
    62461 atatcagaaa ataatgtaga tgtctaatat ttaaagccat attaagtcaa atagaattaa
    62521 atttagtaga acaaagttat tacaattaat aaaagtgagc tcataatacc cactacacct
    62581 tcgtcatctt taaatttaag agtttttact attgaataat aaaggtatat tccagtaaaa
    62641 ataatcttta aatacaagaa aaataaactc tttgggtata ttaaaaagct aaaaagtgta
    62701 aatataaaag caagtagagt acttatcctg taaaagaaat ctatttgtgt aatgtcttta
    62761 tattttatca taaacaccga atataaaatg atgaaaacaa ttgcgacgat tgcatatatg
    62821 gtaaataaca tattttcaag agtaccattt gaaattacta tccacttata ccacataatt
    62881 ggccaaaata atagtgctaa gaacttaaaa taattatcaa acaacttttc tttatacatt
    62941 catcaaacaa cctttcttaa caaaagcata tatttgtttt tagaatttta aataatatga
    63001 tatcattatt atatattaat attgaattta tagaaaccaa aatttgttaa aataaatata
    63061 tagattttac tgttaagcca gttaaaatta ctactatttt tattatgaaa ttggatcaaa
    63121 tatgtagaaa tacggcaaat tagttaatat taaatattta ttatttccaa gttgtaaaga
    63181 ctgttttttt aatgatagaa attctaatct tttttgaaag aaagtaatat ccacattaag
    63241 tatgtctgcc atttcataaa cgcaagtgat gccagagtta attatgttta ttatatcttc
    63301 ttcagtaatt aagaactcac aagcccattt taaggcttta ttttcgcact tatctataat
    63361 aatttttgta taataatcgt tataagagga tacatagtat ccaaggctag tgaaatgatg
    63421 tccaagttct tcagctaaga tggatgtcaa tttttttgag ttttgtttta aattactgag
    63481 taatgatata attttaatac catgtttgtt tatatatagt ccttctaaat cacctgcaat
    63541 ataagtggta taatgaatta ttatctcttc ttgagaagct aattcaaaaa gcttatccaa
    63601 attattcata aaaatccccc taaaatagaa tgtatgtttg cctttgaatt atattaaaag
    63661 agcagaaaaa tagactgctc atcatatggt ttattttttt ttatatttat ttagtaaaaa
    63721 ttctatataa tcattaagtt gttcttgtgc ttcttcaggt aactcttcat gtggattttt
    63781 tctatgtgca gctactgtat caatattttc cttaactaag gttcttccaa gaaggtaatc
    63841 aactgataca ttaaatacat cagccaattt atttaaaatg tgttcatcag gaaatctgtt
    63901 ttctgtttca tagtacccta agactctttg ggaaacgcct actttttctc caagttctct
    63961 ttgagtcaat ccaaattcct ttctaagttc tcttaatctt ttggcaaaca ttataacacc
    64021 accttatgta tagattataa caaattgttc taaaaaataa aactaataaa atataaaaga
    64081 atattttttt ctaaaatcta ttgataaaga acaaataatt ctatataatc taagtgagga
    64141 agaacaaaat attcttaata gtaatggagg tataaaacaa tgtttaaaaa taacttgaaa
    64201 tattatagaa aatgcaaagg tatgacacaa attcaacttg ccagaaaggc tggaattaca
    64261 aatgattata tatctcaaat agaaagaggc ataaaaaatc ctggacttct tatggctaag
    64321 aagatttcta gtattttaga acaaaatata gaagaagttt tttttataca gttatagaac
    64381 aatatgttct tgaaggttgt gagattagta aaaaactgtg cactaaagag attattgtaa
    64441 atttgaagct aataataagt atataaaaaa ggggaagtac tatggaaaac aaaaaagata
    64501 tattatttaa agaaacagat aaaagattac ataattataa gtatttggat ataaagataa
    64561 agaatattaa cttggacata aaaagatgtg agaatgaata ctctggatgt ggagcaatgg
    64621 tatatacaga aaagactagt aacacatata acataagctc ttctgtggaa aatgaggtgt
    64681 taaaaagaga ggaaagatta agaaaattaa aaatggaaaa agaagatata gaaatagaaa
    64741 aagagaagat agaaaatgct ctaacgtgtc taaatgatat agaaatggaa ttttttaatc
    64801 ttttttataa tagtaagaca aaaaacaata tgacatatat ttctatgaaa ctacacttag
    64861 atagaacatc ttgctacaat ttaaagaaaa agatgatatt taaattgagt gagatattat
    64921 aaaaaatagg acaattttac aacactttat atacaccatt acaacaatag gcaataaaat
    64981 atgtgagata atgttattgt gaaagaaatc catattgaag gaggtgatag attgaaaaga
    65041 ataatattac ctaaaaatat agaagatact tgacaggaat aaatgagata tatatttaaa
    65101 aatgacttat atcatttata gtaagattat cagattaagc aagaatattt agtgatagtg
    65161 tggtgattat ttgcttaaat acaaggaaat attagaaaca attattgaga ttctcaaaaa
    65221 aaactttact gaaagtattt ttattgatga tgaaagtgtg caaggctctg aagggtcttg
    65281 tttttttgta agtatactat cagttatttg tacacctgta atgttaaata cgaataacaa
    65341 agatattgtt atctctataa aatacttacc aaaaccacag tcaaagagta ttagaatgta
    65401 tgaagtttca gatgaattaa ataagttatt caacagaaat ataaaggtaa cagacagaaa
    65461 attaaatata acaaagctag aacaaagtat taaaaaagaa gagtcaattt atgtattgaa
    65521 ctttacattt acactaaact atctggatag tgtatatgaa gaagatgtag tatatgaaaa
    65581 tatggaagaa atcaatttaa atttaggaga gtgatagtat ggctatagga ttaccaagta
    65641 tcaacatatc atttaaggag ctagctacaa ctgttaaaga acgttcagct agaggaataa
    65701 ttgcaatggt acttaaagat gctaaggcac taggtcttaa tgaaatacat gaaaaagagg
    65761 atataccagt tgatttatct gctgaaaata aagaatatat aaatttagct ttgatgggaa
    65821 atgttaacac tccaaataag ttattagttt atgtaataga aggagaagca gatattcaaa
    65881 ctgcattaga ttttttagag actaaggaat ttaattatct atgtatgcca aaagcagtag
    65941 aagctgataa gactgctata aaaaattgga taattaaact tagagatata gataaggtta
    66001 aggttaaagc tgtattagga aaagttgtag gaaatcatga agggataatt aattttacta
    66061 cagaagatgt gttagttgga gaaaagaaat acagtgttga tgagtttaca agtagggtgg
    66121 ctggacttat agcaggtaca cctttaagtc aatcagtaac ttatactaaa cttagtgatg
    66181 tagtcgatat acctaagatg acgaaagttg atgcagaatc aaaggttaat aaaggagagc
    66241 ttatacttat taaagaagca ggagctataa gaattgctag aggagtaaat tctttaactg
    66301 aattaacagc agaaaaagga gaaatgttcc agaaaataaa aatagttgac actttagata
    66361 ttatacatag tgacataaga aaggtgataa tagatgacta tataggaaag gttactaaca
    66421 gttatgacaa caaatgttta ttgatagtag ctataaaaag ttatttagaa gaattagaaa
    66481 aatcagcact tatagaatct gattctactg ttgaaataga ttttgaagca caaaaatcgt
    66541 atttaaaatc aaaaggagta gatttatctt atatgacatt acaagaaata aaagaagcta
    66601 acacaggttc taaagtattt ttaaaagcaa aaataaaagt acttgatgct atggaagata
    66661 tagatttatc aatagaaata taggaggatt attaatatgg caaatatgga agctagaaat
    66721 gtaatgagtg gtacttgggg agaactttgg cttgatggaa acaaagtagc agaagtaaag
    66781 aaatttcaag caaagatgga atttacaaaa gaagatatta taatagcagg tcaaatgggt
    66841 actgatacaa agtatatagg atataaagga aaaggctcaa taactctata ccacgttagt
    66901 tcaagaatgc acaagttaat tggagaaaag ataaagagag gttctgaacc taggtttgtt
    66961 gctatatcta aattaaatga cccagattct tatggagcag aaagaatagc agtaaagaat
    67021 atagcatttg atgatttaac tttagctgat tgggaggttg gcgtaaaagg agagatagaa
    67081 gcacctttca catttactga gtatgatttt cttgatataa tttagtttta tatttagttt
    67141 tatatttggt tttatactga tatttagtaa atatatactt aataaattca gatagttaat
    67201 aagtaaaaaa gttagttgat tgaatttgat tgataaagga gcaaataata atgagtgaaa
    67261 atggattatc aaaaaatata aacatagtag atttactttt aaattcagat acagaaaact
    67321 tagaaagacc gagtactata gttgaactta agagattatc aactatattt gggcaggaat
    67381 ttaaagtaat gtgtagagct ttaacaataa gtaaagatga agaaatacaa aatacttgtc
    67441 ttaaaattga tgaaaatatg aaaacggata tagacttacc ggagatgcag atgcttacaa
    67501 ttatagaagg tgtttgtgat ttggatggaa agcttttatt taaaaataag gagctaatgg
    67561 ataaatttaa ggctccaaca ccaaaagaat tagcaagaaa attattatta ccaggtgaaa
    67621 ttaccaactt atatagaata cttcaagatg ttatgggtta tggtaaaaat gcagtgatag
    67681 aagaggtaaa aaactaatag ggacggatac caggactaca ataatgtact attattggaa
    67741 gaaaaaaggt ataagaccgt ccctttttta tgcaatggat aaaggcgaat taaagcttat
    67801 tgaagctttt ttcgccttag aaattgagga agaagttgaa aaaatgaaac atggatatgg
    67861 agtgtgtcct ttgacaggag gtggtatgta atgggaaatg tgagagaaga aggtataaat
    67921 atgtacctta cagataatta cacaccaaaa atgaatcaaa ttatatcagt aactgataat
    67981 tttaggagag caactgtggc tgtttcactt tccactaatg taatggctag tagcataaaa
    68041 aattctattg gaagtgcaag taatagagta aacagtttaa attcctcgtt aagaaaagtt
    68101 caaactactg ctagtagtgt aagttcaact atgacaaaat taagttctag cataaatgct
    68161 gtttcaggag ttattggaag tttaaatgga agtattatga tactagcaat aactatagct
    68221 atgattattg attattttaa taagttgatt caaaagaaaa atgagtttaa ttcaaatatt
    68281 atgattatat taatatttaa agctaaaagt gatgaagtag aaaaaactaa aaataaatta
    68341 cttggaaatt taaaaaagat tggtggcaag gtttggaata tcgtaataaa agcaaaagat
    68401 atgactaaga gagttataag tagtatcttg ggaaaattaa aacaagtaga gaaacgtcct
    68461 tatcaaggaa gtattaatct taaagatatg gtgagtagtg ctatgggtag aattttgcct
    68521 aagttaatgt tgtttaaaaa tactttttgg agtggtgtaa tagctataaa agatatggca
    68581 agtggcatta taagtaaagt atttcccaaa ttgagattat ttgcaggtaa ggtatggagt
    68641 ggtgcaatag ctgtaaagga tatggcaagt ggaatacttg gttcgataaa agggaagata
    68701 tctgatttga caaatggtgc tactataggt gtcgctgtga aaaagggtgt tgatttactt
    68761 ggtcaggaac aaaatcagaa agttgttcta gaaagtgtaa tgaaaagaaa tactggaaaa
    68821 gttaatcaaa tagatgttga tgattattat ggcagtttag taagaatggc aaatgatacg
    68881 ccttttgacc ctgaagatgt tgttgcaatg ggaactaaag ctaaaatgat tagtaatatt
    68941 actggtggca aaaaagaaaa agatataact caagctatgg tagatgttag agctttaaat
    69001 atgaatacaa gtagtgaaca agatgtatca gcagctttct taagtgcagc aaaaggaaac
    69061 atggaatctc ttaatactct ggtaggagaa aattataaaa cttttgatga agcattggaa
    69121 ggcataagtg taaagcagat ggggttagct aaagaaatga gtaatacaat accaggtata
    69181 atatcaggag ctcaaacaag cattaacaat ggcttgaaga gtattgttaa accttttgat
    69241 gatattttag gtcaaggact aaagaaaata aaaactttta tagaaagtgg attaggcaat
    69301 ttagctggct tatctgaaaa aatggctggt aaaataggca atgtaatgaa tggtaagata
    69361 attattggca acaaatatga ccagatgcaa tctagaagtg taaaaaatgg aaaagagttt
    69421 tctgattcta ctcaatatcg aatttctaat gaggctgaaa agcgtaaaat gatggttgaa
    69481 aataagcaag aacgttttga aaatcatgca gcaacaatga tagggaatgc accaaaagca
    69541 attgttaacg caggaagtac actattacaa aatatcgatt ttacagcatt aatagattca
    69601 ttacttccag tagtaaactt agtaaataat ttactagata gtataaacaa taaatcacca
    69661 attgcacaag gattaataag tatatttggt acaatagtaa ctacagcatt ccaactaatc
    69721 ggacctgtag ttgaagctgt tagtcctatt atcacaagaa tttttacttt tttaggtgaa
    69781 tatgcacctc aaataaacaa ttttatagag acactgggtg ttatttggaa aactgtatgg
    69841 gagaccttag gacctctgtt ggaaactgga tggaaaatta tagagccaat attgggagct
    69901 ttttttaaca tattagataa agtatgtaaa atagttaaag atatatgcaa gtggtggcaa
    69961 actatgatta ataagataaa aaatggaagc atcacaggaa cagttttaaa tctagtggaa
    70021 aagagtaaaa aaaattacaa agataatcca tatgctggaa caaaggctgg tgattctggt
    70081 aaagcttatt caggtaagaa aggtaataat gcatttggat tgaactatgt tccttataat
    70141 gactatcaaa ccagactcca tgaaggtgaa atggttttaa ctaaacaaga agcaaatcaa
    70201 tatagaagca gaaaaaatgg tggaaatata aacatagcta agttagctga tacaatagtg
    70261 attagagaag aagctgatat agaaaagata acatcaaaat tagttgcaag tatccaattg
    70321 gcacagttag ggggtgtctt ataatggaaa tgtggcttag acaagctgaa gatagattta
    70381 gatttccagt atttccatct tcctttagta ttaatggaaa agctgctgta aactcttcta
    70441 gtatactcaa aataggtgaa atagcaactt ttggtggtgt agctcttaaa agcatttcaa
    70501 tatcaagttt ttttccaaat aaagactata ctttctgtga ctatacaggt tttccatcac
    70561 catatgattg tgtaaataag atagaaaaat ggatgaagga aggttttata ttaagattta
    70621 caattacgga aacaaatata aatatggaag tcataattga agggtttagt tatgaagaaa
    70681 gagatgggac tcgagatgta tattttacat tagatttaaa agagtataaa agaataaaga
    70741 taccaaaagt aactccaaaa caataactat tatagataat aagttataaa taactgctta
    70801 tagaattaaa tgaaaaggca ggtgattttt tattattaag atttgggtac acataaaaaa
    70861 cggaagtata tatgacataa ctgacatagt agacaaggta tcatggtcag gtgattataa
    70921 atctccatca aggacactag agttttcaat aatacaatca tcatttgatg taaatttcca
    70981 acaaatagat ataccaatag ctagtacagt ctgtttctat gtagatgaga aagaactctt
    71041 tagaggaatg ataattaata ggtctaaaga ttcaagcagt aatgaaatta gttttgtatc
    71101 taaagatatg ggatttttac ttacacaaag tgaagtgtca tacaatttta aagataagtt
    71161 agttgaagac atagcaaagc aagtatttgc tgaaaatagg ctttcagttg gaacaatagc
    71221 aaagaccaat gtcaagtata caaagatgtt tataggagta aatggttatg acacaataat
    71281 gagtgcatat acagaagcaa gtaaaaagac aaagaaaaag tatatgatag aggccaattt
    71341 agataagttt aatgttattg aaaaaggaac tgttacatta aatgttatgt ttgaagaggg
    71401 atttaatatt ataaatacca ccttttcgga gagcatggaa aatgtaaaaa ataaagtaat
    71461 agtggtagac cagtatggaa gcaagattag cgaaaaaata gataatgaaa tttttaagga
    71521 agtaaatgta ataatgcaaa aagtaattca gcaacaagaa aatcaagatg tagatattga
    71581 tagcgagttt aatgggatag aaaaaagctg ttctcttaaa ggttatggag atgtaagttg
    71641 tataactggt agaggagtaa aagttaaaga ttcttataca aagcttgtag gactatttta
    71701 tatagataca gacaaacata cttggcaaaa tggagaatat caaattgagc ttgaacttaa
    71761 ttttcaaaat cttatggatg aaaagtcagc aggacaggat gaacctaagg aagaaagtaa
    71821 cttaggggga gaagattatg caggaggaaa agagtttaca gcagaattta cagcttactg
    71881 tcctagaaaa gaagaaggtg gagatacaga ttgtagaaag aaaaaacttg acccatctaa
    71941 aaaaacttgc gctgctccta tggttggtaa atatgaacaa acttattata caaaagagtt
    72001 tttaaataaa catcctttat taaactatgg agatgaaata caggtaatta caggagtttc
    72061 tggtcgtgat ggagtctata aagtaaatga cgtaggacct gcaataacta tagaaaagaa
    72121 tggaacatac catatagata ttttatttgg aaatgttgaa gaagctagta aatttggaag
    72181 aagaaaagga aaaattatta ttggtggtta ttctggtaat gtatctgata aagctaaaat
    72241 agtaatatca gaagcaaaaa aacatctagg taaaccttat aaatggggtg gaaatggacc
    72301 aagtagtttt gactgttctg gtttaatggt ctattgtttt aaaaaagtta atgttagttt
    72361 gccaagaacg tcaaatcaac aatctaaaaa aggcaagaaa gtagaacaaa aaaatcttca
    72421 agcaggagat ttagtatttt ttcataatcc agtcagccat gttggattat atataggtaa
    72481 tggagaattt ttacatgctc cacaaaaagg tgatgtagtt aaaataagta agttaagtag
    72541 tagaagagat tttaatacag ctaggagagt attataaaag gatggtgata taatggctaa
    72601 tccaataaat gaatttatag gaataataag agaagaagga aagtatcata atcaaccttc
    72661 tttttttatt ggaaaaatta aaagtaaatt accagattta aaaatagaga caaataacat
    72721 catattagaa aaagaagata ttttgataga tagttggatg attgatagac agctagaaac
    72781 atttgacaca gaaacaaatc aagaacacca gcatgaagta aaaaatcctt ttatagataa
    72841 ttttgaatct ggggatatgg taataatgtt tagaataggc gaaaaatttg ctgttgtaag
    72901 taagttggtg agcttataat gagtacaata tttcctttta taggtgtccc agaggattat
    72961 atcttaccta aaacagaaga attgccaatc tttcgtgaag tggcatggga ttttgaaaaa
    73021 gatgaaccta ttttagaaaa aggtgacttt aaaataattg aaaaaaaaga agccttaaaa
    73081 gtttggatat acaagtgtat aaagacaaat agatatgaac atgagatata ctctttagaa
    73141 tatgggacag agctttcaga actaatagga caaaaatata caaaaggtct tacagaaagt
    73201 gaagctagta gattcataaa agaggccctt ctaataaatc catatatatt agaagtaaac
    73261 gtaaaaagtg ctaactttaa cagagacgta ttgagtgcaa atgtaaaagt atccactatc
    73321 tatggggagg tggaaataaa tgtatagtga ccagacatat gaagtaataa aaaatagaac
    73381 tcttgaaaat attaatcttg atatttataa aggagaaggt tcttttctaa acaacatggt
    73441 atctggaaat aatctagaac tttcaaagat atatctagaa ctttcaaaga tacataaaat
    73501 ggcttttata caagacacat ataaccagtt tctcgataaa agagtcaatg aatttggtgt
    73561 atatagaaag ttaggtacag agtcaaatgg agaagttgaa tttattggag agaaaggaac
    73621 tgtaataaat aatggcacaa taatatcata tagagattta ctatttgtag taataaaaga
    73681 tgtaactatt ggtagtgaag aaggtgacaa tagcccagtt caagctctgg aagttggtaa
    73741 gaaatataat ttacctacaa attgtgaatt taaactagtt gataatatat ctggagtaac
    73801 aaagattact aacacaagaa gttttgaagg tggtacagat atagagacag atgaagaact
    73861 aaaagaaaga ttttataaaa tccaaagaaa tcaagctaca agtggaaata aagctcacta
    73921 tgaagaatgg gctttggaag tagatggagt ctataatgtt aaggtttatc caagatggga
    73981 tggtccggga acagttaagg tcttgatatt tgggaaaaat aatcaagctg ttgatacaga
    74041 aacaattgaa aggtgtcagc aacatataga tgaagagaag cctattggac caactataac
    74101 agttgtgaca ccattaccaa tagaaataaa tataagtgca gtaatgaaat tagaagatgg
    74161 atatacatta gacaatgtaa aagaatcttt cctagaaagt ataaatacat actttagaga
    74221 tattagagga gagataatct atacaaaagt aatgggaata cttataaata ctactggtgt
    74281 acacgattta agtaacctac ttataaatgg aagtacagat aatataacta ttaatgaaga
    74341 taaaatacct agtgtaacaa ctgttaattt tagtgaggtg gaaaatcaat gaagctaatt
    74401 gataaactac catcatttga tagaaattac attgtagagg agatacaagg tgcatacgat
    74461 acagaattaa atattcttaa agaagatatt gatgatacct ttaaccaatt atttgttgac
    74521 actgcaacat ggggattaga tatgtgggaa gacatactct gcattgaaaa aaaagaactt
    74581 gattttgaca caagacgtag caatataaaa gctaaaatga gaagcagagg tactagtact
    74641 attgaagtta taaaaagtat atgtgaggca tatacaaaat cagaaacaga tataaaagtt
    74701 tatagtgatg aatttacatt cgtattgagt tttatagcaa ataattgtga ctataaaact
    74761 cttttagatt gtagcgatat gattgaaaga gtaaaacctg ctcacttatt acactattta
    74821 gaaccaataa tactagataa aagtatggtc tattgtggtg gaggtatggt atgtagtgaa
    74881 gaagtaaaag ttcatccata ctttgaacca attataaaat gtagcgctgt tgtaaactgt
    74941 ggagctggaa tgttaagtag agaagaaata aaggtttatc ctttaagcat taaatgcatt
    75001 gaaaataatt gtaagattaa tatagctatt gcaaatgata caggcgtaga aaatgtagta
    75061 gtttatccta aatcggaggt ggtataattg gaagaaaaat tttatataat attaaccaaa
    75121 attggtagag aaaaaatagc aaatgcaact gcactaggag agcttgttgg attaaccaag
    75181 tttcaagttg gagatagtaa tggagaatat tatgagccaa cagaggaaca aactgcttta
    75241 aagaatgtag tttgggaagg aaatataaat tctctaagaa ttgatgaaaa aaatcctaat
    75301 tggatagtta tagagactat tttaccagga acagttggtg gatttatgat aagagaagct
    75361 gctgttctgg ataatgagaa taatataata gctataggta agtatccaga gacgtataag
    75421 ccacgtgctg aagatggcag tattaaagat ttggttgtaa aaatgatttt acaattgtcc
    75481 aatacttcaa atgttacatt agaagtagac ccgacgttgg tttttgtaac tcaaaaggat
    75541 attcaagatt tagatgataa ggttgataaa aatataaaag aaataaaagt aaaaattgga
    75601 gaagaactct tatctacaga agctaaaaac ttatcaggag ctataaatga ggtagtagaa
    75661 aaaattaaaa atatatctat tgatgatgta ataggaggtc aaatacaaac tgaactatct
    75721 gtattaaaaa atagttacaa taaattatct gaaaaagtat tagatatttt aatatactta
    75781 gaattagagt cagaaataga tgtagatgaa gctggatatt ggtatgatac cttaactaat
    75841 gctaaaaaca taatagctat agaaggcctt aagttagatt taaatagaaa gtgtataact
    75901 ggagaacttg gtagtgttac atttaagaat gtggttctac catttaatgc aaatagagtt
    75961 agatatatac atgaaatgga taataacttt gttgaaacaa aatctaatag ggcatattca
    76021 attggccaga cagatataac tttaaataaa tattcgtatg aaataagata attaggaggt
    76081 ttttataatg aaaagaacta aactacttca aagaggtaat ttctttggcg ataaaaatat
    76141 ggtagttgat gaatttgatg aagggtatga taattatgac tttattaatt tttttactgg
    76201 atgttgtaac tatacatttg gtctaaaaaa taataatatc ttgtatggat gtggagataa
    76261 tagtaacttt caacttggat tgggagaaga caatacaaca agaaaattat ttacgaaaat
    76321 accaaatata tctactaata ttaaaaaagt tgcatgtgga gaatctcatg cagttatact
    76381 tacttcagat ggagaattac ttgtcgcagg tataaataca gatggtcaaa tgggattggg
    76441 attagaaaaa gtaggaaaaa cagtttccac atttgagaag gttccagaaa taaaaggcgt
    76501 aaaggatatt gcatgtggac ttcaatcaac atatctttta tacaatgatg gaactttata
    76561 tgttgctgga aataatttgt atggtcaatt aggtctagga actaatggag catctgcaaa
    76621 tgtaaataca tttataaaag tagatgttga taatgtaaag gctgtattct catataataa
    76681 atcagctttt ataataaaga atgacaataa atgttattct actggtttta ataatcaagg
    76741 tcaactaggt ttaggagata agaataatag agatttattt agcttagttt ctattaatga
    76801 tgttaagact atagcttgtg gttctgaaca cactgtgtta atgacgtata ataatgatat
    76861 atatggttgt ggaaaggaaa aatgttttgg aaatgcactt caatcatcac tatttactaa
    76921 gatagaagaa gtaaatataa aaactattgc atgtggtaat ggtaatacta tgcttataga
    76981 taataaaggt attttgaagg ttgctggaaa taatgatata tatcagttag gtatagcaaa
    77041 ttactctgag aatatagata attcatttat agatttaaaa aatattgtag ctaagaatat
    77101 tttcattggt ttatcacata gcatactaat tgattcaaat aatgattcat attgtacagg
    77161 agataatact tatggacaat taggttcgtt ttttgatgat atgcacattg tagaatttaa
    77221 gaaaatggat agtgaaaaat atagttatag taattatata aatttaatta aatctgagga
    77281 taaattaact ttattaaaag aagaaatgga aataaaggat attgaacttc cactagatat
    77341 acattctgta agagatgtcg tttttagtcc ttattgtact ctggttattt tagggaatgg
    77401 agatgtatat ggtctaggaa ataatagata caaaggaatg ggttctgact taccaagtca
    77461 attaaatgag ttgacaaaat taagtatctc taatgtaaag tctatagtag catcaaaaaa
    77521 tatttctgga ggaatattct acattaaaaa tgatgacact tgttattatt ctgggccaaa
    77581 tagtaactca atagcaggtg ttcttccttc taattcagat atatttaaga aaatatctat
    77641 agataatgta aaaaaagttg ttataaatac tgatttatca aactggtttt cattaattgt
    77701 aactaataat aagcaaatat atacttctgg aaagagttca agttatgtta atggacttag
    77761 taataaatca gcaagtcaat atactgagat tggtgttagc aatgtaacag atgcatatag
    77821 ttcatataat gcaacattta ttgtggctga cgaaaaaaag gtatatgcaa ctggtataaa
    77881 tacaaactat ttattgggtg ttaatcctaa tgatggagtc aatataaatt taacattaat
    77941 aaataactgg ttttatgtaa atccttcagg agcaagttat agtacaaatt cttgtacaaa
    78001 tgatattact aaaattaata atattattat atatgaatat atggctatat tatgtacaaa
    78061 ttatggttct tttttaactg gataccatgg tactttatgg acaaagccaa gtgattctac
    78121 ttatagagtt caacaacaag gaattacaca tgctggatat attagtaatt acatatataa
    78181 ctattatccc acaaggtgta cacaatcatc atattctaca aattttgcct atttgtatta
    78241 tggagaatca acaagtaatt taaaaaatgt aaatccagat aatttactta tttctggagg
    78301 ttcatcttat atacatcaat atggaaggaa ttatcttaac aatcaatcat ctaataatat
    78361 tgcagcatct aatataaatt caggtcctat tacctctgat aaagccatat ttttatataa
    78421 agctctattg tatttatctt ctaacacgtt atatggtttt gggaatatat ctgaaagtgc
    78481 aaaagaacta gatgtttcag atacacaaga tggatataat gccactaatt ataaaaaggt
    78541 aatgaaaaat ataaaaaata tatttatacc tccttatgat ttaagtagag ataaaactag
    78601 atttgcaata ttaactgata agagcttatt tatatgtgga tataactcta agggtacgca
    78661 tggtatatca gttaatagta gtttaaattt aaataataag ataaattaca ataaaaagaa
    78721 tagcagtagt gaaatatctt ctaatataca agaaatatat agccattcga agtctacata
    78781 tttattaact aataataata tgctttacag tgttggttta aatgatgtag gtcaattagg
    78841 agtgggagat gagataaata gaaaggtatt tactaaaata aatattgata atataaaatc
    78901 tataaatgta aatagattta ctgacaatag taaacatgta tttgcgataa aaaatgataa
    78961 tacctgttat gctgttggtt taaataattc tggtcagtta ggaataggag ataatgtaaa
    79021 tagaaatgta tttactaaaa taaatgttga aaatgtaaaa tatgtagctg tatatggaaa
    79081 cacatctcta ttattaacta atgatggtct tttatatgga gcaggtaata atggaaaagg
    79141 acagttagga ttgggtgata ctacaagtag gaatatattt acacgtatac ctataaatgg
    79201 agttagagat gtgtatatat gtaatgatgt atcaataatt gttaaaaatg ataatacatg
    79261 ttatgtatgt ggatttgtaa atggatattt tgggtttact gaaggaagta taagtacatt
    79321 tacaaaaata aatattgaga atgtaaaatc tgttgtaaca gcaggaagtg aagctacatt
    79381 ttttataaca aatgacaatg ttatttatac tacagggaaa aaagagaggg tattcttttc
    79441 aacagaaact aatgatataa agggtatacg agtaattaat aatattataa atgcaaaaaa
    79501 aatagtagtt aatggatata cttcagccat tttaacaaat gacaataaac tatttgttgg
    79561 aggtcttagt ggatatggaa gtatagcaaa taataataat acaaatagtg tggaagatgt
    79621 taaagatgtt tttgtaacag ctaataatac actttatata gataataata acaatttgat
    79681 atcatcaggt agagatactt atggtatatc tgatgaatct tatagggata tgtcagttcc
    79741 atattataaa gtatctataa agaaagatgt tgatactgta ttttctagtt acaatactat
    79801 atttattaaa gatatatatg gaaaatttta ttcttcaaca ggagataata gatataatca
    79861 tttaggtatt caccatagat atgataatga taaaaatgaa gctcttgaag gttccctaca
    79921 ttcatatttt aaaacagata acacatcaga taaaatagtt tttaataaga aaaatgaaaa
    79981 gctagtaatg tttaatgata agtatataaa aacaaataat aagtatataa attataaaaa
    80041 catatttaaa gataatttta agtatacttc aataatattg ccatttgagg tatctgatat
    80101 tgatatatca aaaacacatt cattggctgt tgctaaggat ggcaagttat atggaatagg
    80161 aagtaattca tataaagaaa ttaatcaaac ccttgaagat atagaattat taactcttac
    80221 tgaagtaaat atatcagatg tcaaaaaagt tgcttgtgga gataactact cctatattat
    80281 taagacagat aatactctat ggtcatatgg aaagaatact gagtaccaat tgggagttgg
    80341 ccacaataat gatgtaagag agttacaaaa ggttactgga ttaccttctg ttaaagatat
    80401 aagtatatat aactcaatga cacttgtttt aactaatgag ggagagttgt acgctcaagg
    80461 gtacaataca aatggattat ttggactagg agaaagtgaa aaagataaga taataagaac
    80521 ttttactaaa gtattaacta atgttaaaga aattaagtca cataatgatg accacatact
    80581 agtaattaaa aatgataata gtctatggat aactggtaaa aataaatcta tgtataaaat
    80641 atctatatca attactgatt tatatgaatt tactaaaata ccaattcctg aacatctaaa
    80701 tgatatttta gatatagagc tttcagatga tacaatatac atgataacaa aagtagatac
    80761 aagtaaagca tctatagaaa tagttgaaaa atcaatatct caagtgagag ttgtagtaca
    80821 agaccctaat aatgttatag aaaaacttga aatgtttata aatgatgaat taatatctac
    80881 taagactaat ttggaaataa atagcattat atttgagata ccacaaaata aaatagtatt
    80941 aggagaaaat aagatactga ttaaagccag tagtcctaca ggcgatttat attcaagtat
    81001 gtttatattt aaatcagaaa cagggcttaa agtaaaaaag gattctattt taatgataaa
    81061 caataaagta tattcaatca taaacattac tgaaaataac actgatttaa tagtaacatt
    81121 aaatgaggga ttaaaggatg acatgatgga aaacaatcct atatatcaat taataaataa
    81181 aactaaagtt caagtaaaaa taaataaatc tgacttattc aaagacatga aactagttga
    81241 aatcaaaaaa tcagactcaa gttaccaaga aatctatgaa ttagaagaag ccaacataaa
    81301 aagtgctcag cctaaaatca tagtagaaaa aggagataaa tggacagcta taaaacgtcc
    81361 atctatgatt tttagatatg atgctgaaag caacgagcca caagcttaaa atggaggtgt
    81421 gaaaattgtt taaattcgat aaaaataaaa tagaacaaat caaacaaggt agaaaagtag
    81481 aaatgcagta taaagacatt tcagacataa gtataggtca agtaaagcaa gatgatgata
    81541 taacaaataa ttttatagca aatgcagaaa tatatgagat gttgttaaat caaagttctg
    81601 tcaatgaagc aagtaatata agctctttta gtgtaagaaa atctggaggt gagagtggaa
    81661 tggtagaagt atatgtagct ttaattttaa gaggcaaaaa aacaatagaa gaagtaccag
    81721 cagtaattag agagcaagtt agaattagat gcaaagaatt agaaatacca gttgaatagt
    81781 aaatttagaa taactatgta ttagttattt tttttatgta aagtacaagg tcttaacttt
    81841 aataagtaag ccttgtactt attttttgtt atattagaaa ttgtatatat atttattatt
    81901 tattcaatct ataaattgca cctacaattt aaagtacaga agattaaatt gataatcctg
    81961 aaaatataat attgcatgat gtaagaatat aacaaaaatt aaagctataa gtataaaaaa
    82021 tttagacaat aggaggctat aatggataaa ttaataaccg aattgagtag tctaggggca
    82081 ataggtatac tatgtgctct attatttaaa aatactatgc aggagaaaaa agaagataga
    82141 gacatgtata aaaaaactgt agaaaatttt atagaattat ctacacaaca acaagaaata
    82201 aacaaaaata tacttgttca aatgggtata atgaaaacag atgtagagga aattaaggaa
    82261 gatgttactg gtataaaagg tatgttacaa aacggtgtat aacatgaaag agtagcacca
    82321 gattatatat tgttaggaaa agataaagta gtattgtaga tagtacccta ttttattgag
    82381 aaggatttga tatttaaaaa tattaattaa aaaaagtaat aaaaataata tataaaaata
    82441 atatataaaa attaaaaaag gagttgagct taaatttgat tagaaaaaat caattttaag
    82501 acaactcctt ttttttatta aattattgtc tattaaccaa aatagctatt ttagcatctg
    82561 gattataact tatttgaacc atttgatttt tcttaacatg ttcaaggtct tcaccaccat
    82621 aagctatttg taacttaact ggtaacttac cttgttttat aatagcaacg tactcttttt
    82681 tacctttttt ctctaaacta atcaaattgc caacataagg tttaaagttc tgatactttt
    82741 tactagaatt tcttatgtag aagaaagcac caacagcaat aactaaattt atgccaagtg
    82801 taacccaaga attgatttta agcatagctc cagcgattat tatcacgaac attaaaacga
    82861 taggtaatat agctttctta agaagcaatt tacccattat ttcattagcc tttttctcag
    82921 ggccactcat agtttttgat ctagcaaatg attgcgcgaa tttgtctctt aagcccattt
    82981 tatcctccta attttaataa atatttagtt ataataacga gatattactt gaaactaaaa
    83041 atttactaca tttatattat gtttgacttt tgtataaata attacattca agtaaagcaa
    83101 aatatactaa ttattttatc ataaaattat aaaaaagaaa ataaatgaaa taaaaatatt
    83161 agaacaaaga aatgatgtaa aatcgtatca aaagcaacat aaaaattatt tatctatttt
    83221 ctcatcttta tttttgttat actcaatttt tcctaaatcc ttctcttttt catattcatg
    83281 aagttttaat tcaatcatac cttctatttt ggctttatca taatcattta actttctaaa
    83341 attgtttaaa agctttattt cattagagtt tatgctatta agtggatagt ttgaggagga
    83401 atcgcaaatt aaatctgatt tatgtgatag attatctcca tttaatagcc agtctactga
    83461 aacattaaat atctcagcta tagattttaa tatttcataa tttggttttc taatgtttct
    83521 ctcaaattta cttaagttgt cacagcccaa catttcttct agttcatatt gtttaaggtt
    83581 ttttgctttt ctcaaataaa caattctttc tcctaaagta tccataaaca ctctccattc
    83641 aattaatgtc aaaaagactt tttaagatgt aaatagtttc aaatttaagg tcaaaatgac
    83701 ataaaaagca ttgacttaag gtcaaaatga ctttataatt aacttaatga tacgaattta
    83761 catcctaatt ttagcacaaa gtaatcaaaa aatcttattt agtattaaat aaatttatat
    83821 acttaatatg tgtacatatt aaaaatatat actaaataga gggggtgtgt aagctaaaat
    83881 aatataaaag taaatataaa tcacttagaa aggaagttga taaatggatg ctcgaaaaaa
    83941 atggatacct tttttgggag tgcaagtcaa gcaaagactt attgaattaa atatgactca
    84001 aagggaatta gcgaagaaaa taggtgttaa tgaaaactat ttgtcagcta ttttaaatgg
    84061 aagaagaaca ggtaaaaaat ataaatcatc aatttatcaa ttacttaata tagaatattc
    84121 agaagatgat taataaatag tatataaagt aggtgaatat tcttgtgtgt aaattggatt
    84181 cagatggggt tatagagtgt tgtagagcaa ttgatgattt tattacagca ctcagtaata
    84241 taaaaagctt aaatatggaa agattaaata ctttaactaa atattctagt acatgttcaa
    84301 tccttcttaa agaggggaat tatgaaggat gtacaattgt gtatagaaag atgttggaag
    84361 aattaaaaac atgagtaatg catttcttag gaatataagt tatacataga gatgtattat
    84421 atttttcaaa gtacttaaac taaaatatgg ataagataat ctaaatatta taaatgtgct
    84481 tgaaattaga ctatacttgt ttttaaataa tccaatatcc atattttagt aatatactac
    84541 aaaaaaagaa ggttaataga tgatgtaaaa tcgtatcaaa ttatgtatgt ttaaaccatt
    84601 ttatcttcat tattattaga ggaatgcttt tttaagtctt tatattcaga tatcttaagt
    84661 tcaagtattc cttctatttt tattttatca cgttcgttta gttgtctgta tagatttaat
    84721 atcgtcattt catcattagt aacatgtaag taatcttctt tatcttcttt tacactacta
    84781 ttgacattta ccttctcttt accatagaga agccagtcag tcgtaacatt aaaataatca
    84841 gctattgaca ttagtatatc acaattaggt tttctatctc ctgtttcata cttgcctaag
    84901 ttttcaaatt ttaaaatatc cataagtttg cgctgagtaa gttttttgga gtttctcaaa
    84961 taagcaattc tttttcctaa agtatccaca aaatacactc ctttcttttt atgagtaatg
    85021 tctaaatgac atttaaaatt aaaaatatat aaatttataa tataaaacta ctaaattaaa
    85081 gtctaaatga cattttgctt aaattaatat gctcataata tgattttaac atattatagt
    85141 tgaaaatata tggtttattt tgatttgtat atataacaat aggtttaatt gttatataaa
    85201 tgtaaagggg tgtatgaata gattgtataa atttatttcg ataaactaag attgcttttt
    85261 gattgtctgt aaaagagaaa aagattaaga gaaaaatagt attatattgt aatttatatt
    85321 aatcaattac aaaaatttta tgaatttatt ctttagaata aaatatttaa gaataagata
    85381 aatttacaat ataatactat aacactcttt tatctagttt tattttcttt atagaacaat
    85441 aatattataa atgctagtag atttacacag aatactgtta tatacatctg tttaaatcct
    85501 gagtttagag tagattgtag tgtgttttct atttttgttc tattattttc tatggaattt
    85561 atataatcca attttgattt atcaaaagcc tttggtattt cagtttttac ctcttgtgtc
    85621 tttgctaaaa ctgcttggag tgattttttt tgctgttgca ttgtatcaag gcttttttcc
    85681 atgtctttct tttggcttat agaattattt aacttgcttt gtagctcttt cttttgagat
    85741 tccattgttc ttagtttttt acttaattcg ttcttttgag ttttattttt ttgtaacttt
    85801 gtatttaagt catctcttgt cttttttagt tgctgtattt gagcatttaa actttctttt
    85861 tgttcattta catttggttt attctcgctg gaattgttat tcttattttc tgtagaatca
    85921 ttcttagtgt cgtctgattc agaattactg gtattactct ggttttgttc atttgagtta
    85981 ttttcgttat cagtaggagt tttttctgta gtaggtattt tattataagc agttgtaagt
    86041 tccttgatgg cctcatcttg tttttcaaga ccttgttcca taccttttat acctttatca
    86101 acaccagcaa tacctttttt tacaccatct attccttgat taataccagc tctagctttt
    86161 accatattgt caataccagt ttgaactcct ttaataccac tatttagttt attttcacca
    86221 tcttcaatac cgtttattcc actttgtgtt ccatctattc ctttttgtac atttttctgt
    86281 attttagtaa ttatagatgg aactttttca tcaaacattg ttgttgatat ttcttttgtt
    86341 atattggtaa tgttggttgt atctgctgac tgaactttat taagtaagga ttttggaagt
    86401 ttgccacctg tcatgtccat atttatattt gaagtatcat tcatatttgg gatagagaca
    86461 ttttttaaat tttttgccat ttcagggtct gattttaagt catctatcat gttttcaagt
    86521 tcttcaagtt gaactatttt aggagttgag ggctttccaa ctaagtccat aatattatct
    86581 tgcacagata atcctgcatg tgctataaat ccaatcatta tagctggaga aattgaagta
    86641 ccaattgagc gtatcaagga taatgttgca agtgctgaat tagattcttc taatcttgta
    86701 tttgataaca tcatatagtt tagaggagtt cccatagtaa atcccattcc taatcccata
    86761 aatattaaac ttacacatac actaaataca gtattggttt ttagagcaat taaaactagg
    86821 taaagagagc ctatcataga tacagaaaat cctagtaata gtattttttt tgccccaaac
    86881 ttgtcaataa gtcttccgct taaaggagca gcaatacctg caaataatcc caatatagct
    86941 acaaaatatc ccccagaacc agcatttatc tttaatgcat tttcagcata ctgtggaacg
    87001 aataccatac ccatcattcc aataccaaca attaaagata aaataagtac tatcaatatt
    87061 ctcggattta aaaaatattc aaagcttaaa atagggtctt tagctctatt ttcaataaat
    87121 atgaaaatag gtataagtac aataaatgtc aataagtatg gataaactga tatatcttgt
    87181 atagaatttt taaaattaaa aaagtctata ttcataagac catataatag tgatacgatt
    87241 atacatatca acatcaatgt accaagctta tctatttttt ctttagattc agacttattg
    87301 tttttaatac agaaaactcc accaataagt atgattaaac aaattggaag atttacaaaa
    87361 aatagccact tccaattttg agttccaaag atacttagaa ttgtgctacc aatgcttgaa
    87421 cctaaaatat tggcaatacc atatgttgcc ccaactaaac ctaaagccat gcctctttta
    87481 ttttctggga aggtagttcc aaattctgct gtagcaattg gcatgattcc accaccacca
    87541 attgcttgaa taacacgacc aattaataaa atatagaaat tggaaaatag tgatgataat
    87601 ccacatatta atgaaccact accaaataga aatatactaa ctagatacac atattttctt
    87661 cctattttat ctgctaattt tccagagata ggaattacag aagcgtatgt taatgtgtat
    87721 atggtaatca tccaaattcc cgttttttca tttactccaa ggctattttg tataatcgtt
    87781 cttgctggtg atactattcc agtatcaata gctcccataa atatacctaa tagataaagc
    87841 gtaagtacta aaaatatttt tggattactg tccttgttct taatactagt attatgattc
    87901 aaggtaaaca ccaccttaat gtattaattt ttcaatatag ggttttaaat cttcaaattc
    87961 tatatgaaga tatgttgaat atgaaaaaaa catttttatt atgatattgc atactaattt
    88021 gtcattatta aaaaaacttt ctttttctaa agcttcatat actttatttg aaagctgttc
    88081 atgaaagtcg tctttgtgtt ttttcatttc aaaaaatctc tctgtttcaa aagtgtttaa
    88141 aaagtcattg tattggatat tatgaacttt gtttataaaa tttcttattt cagtaaaaat
    88201 aatgtttagt ttttttatgt aatcttcagt gtttttattg gagtattcaa ttcgccttat
    88261 caataaatcc cattcagatt ttgtgatata ttctattatt tcttgttttg aattaaagta
    88321 attatacact gtacctgcac ttataccaca cctttgagct attttcctta tgctaatatt
    88381 cgagtaatct tcttctaaaa tcatatcccg agacactttt aatatatctt cttttacatt
    88441 ttctaaaatc tttggcatat taccacctct tttattaaaa ttattatgaa cactgtttat
    88501 tatactcctt taaaatttat taatcaatat gtaagctata atgtataata ttattatata
    88561 gatatgatag aaaataagtg tcttcttact aaatatctat tatattaaat ttgtacttaa
    88621 gtatgattat ttattgaaat atgtgatatt aaatttttct ttttaataaa ttaaatatta
    88681 tatgataagg agaatatggt gatggaaaag aagtatgtaa tggcattaga ccaaggaaca
    88741 accagttcaa gagctatact atttaataaa aaaggcgaaa tagtgaaaat tgcacaaaaa
    88801 gagttcaatc aaatttatcc aaaagctgga tgggtagagc atgaccctat ggaaatatgg
    88861 gggtcacaaa gtggggtaat gagagaagtt atagaaacag caggtataag accagaagaa
    88921 attgcttcaa tagggataac taatcaaaga gagactacgg ttgtttggag taggtatact
    88981 ggtaaaccta tttataacgc aatagtatgg cagtgtagga gaacgtcaga aatatgtgat
    89041 gaacttaaaa ataaaggatt ggaagaatca ataaaagaaa aaacaggtct tttaatagat
    89101 gcatactttt cagcaacaaa agtaaaatgg atattagata atgtagaagg agctagggaa
    89161 aaagcagaac aaggagagtt attatttgga actatagata catggttaat atggaattta
    89221 actcgtggaa aagtacatgt aacagattac tcaaatgcat ctagaacaat gatgtacaat
    89281 ataaatgatt tagaatggga tgaggatata ttacgagaat tggacatacc aataagcatg
    89341 ttgccattag taaaaccttc tagctatgtt tatggtcata cagatgagcg catgttatca
    89401 ggagctaaaa tacctattgc gggatgtgct ggagaccaac aagcagcatt atttggtcaa
    89461 aattgtgttg aagaaggtac tgcaaaaaat acttatggaa cgggttgttt cttgcttatg
    89521 aatacaggca gtaacatagt taaatctaag catgggttac ttacaacaat tgcttgggga
    89581 gttgatggaa aagtaacata tgcattagaa ggaagtatat ttattggagg agcatctgtt
    89641 caatggctta gagatgaatt aaagataatt gaatctgcaa aagatagtga aatgtatgca
    89701 aatagggtag aggatactaa tggtgtatat gtagtgccag catttacagg tcttggagct
    89761 ccatattggg atatgtatgc taggggttca attttaggac ttacaagagg agcaaaaaaa
    89821 gaacatatag taagagccac attggaatca attgcttatc agacaaagga tgttttagaa
    89881 gcaatgcaaa acgattcaaa attaaaacta aaatcattaa aagttgatgg tggagcaagt
    89941 aataataatt ttttaatgca atttcaatca gatatattaa atgtagatat agatagaccc
    90001 aaaatagtag aaactacagc tttaggagct gcttatttag cagggttgtc tgttggattc
    90061 tatattggaa gaaatgaaat tacttcaaag tggtcagtag aaaaagagtt taatccaaat
    90121 atgagtgaag agaagagatg taaattatat aaaggatgga aaaaagctgt atcgagagct
    90181 ttaagctggg aaaaagaaga tgaattggat atttaaaaat taatcaaagt taaatttatt
    90241 tgaatttaaa aagagcttta tgtaaaatat gaagctcttt ttttgttgtt aatcttgcat
    90301 ttttatataa tcacactaaa ttatataatt tatttttcgt tttcatataa aaacattggt
    90361 atagaattgt aaatgtgttg gtcaccaact actaagagaa tgtctccttc taaaaattca
    90421 atatatggtc caggagatat tataagttct tcacctcttt taattgcaac tattgtagca
    90481 cctgtatttt gccaaaattt agtttgtgca gctgtttgac caatatattt gcaattagaa
    90541 tttatggtga actgaacggg cactaaagga ttgattattt caagtctgtt agaatagtct
    90601 aaaattttat ttatagtatc taatatttca ttttctaaat tagatttagt atctattaaa
    90661 ttataaagtg ttgatttata tgatgatata tttgtaatat ctctatattt ttttataaaa
    90721 gaagaagctt tgtctggaga tagtacaata acacctttac cctttatgct tttaacaacg
    90781 ccaatgtcct ctaaaatttt gacagctctt cttatcgttt ctggagatac attgtattta
    90841 ccagccaaaa cagagcgtcc aaatagtact gaatcctctt gtatttcacc cgtgtatatt
    90901 ttatttgcaa tatccaacgc tattttttgg tatattggca tcgtatagtt tttatccatt
    90961 gtttttcccc caatacaaaa tttatgttaa aaaaatatat aatcttaaca atactattgt
    91021 ataatttata ggtttatatg tctacaatat gtacaaatat tgtgcatgtt ttaaaataat
    91081 attttaacat gcatttagta tacatgattt tattatactt aaaactatat aaagaattaa
    91141 ttataaaaat ataaagatat tttacttaca aagaatgata attatataga tgaaagaaac
    91201 aaatgaatga agaaaaatga ttctgtcttg catataaagt gattaaaaat gaaaaatact
    91261 ttaaaaatga aggttaaagc ccttatttta agtgaaaata attaattatt aactaaaaaa
    91321 tggtaaaaag attttttgaa aaagaaatac aaatgaatgt tcaattaaaa taattgcaaa
    91381 aatattcctt aaatggtaaa attatattaa ttaaatgcaa tagaatagtt gcaaaaataa
    91441 aattgaatac aagtgataaa atatttcatg caatatataa aataaacaaa atttaaaaat
    91501 taaaactact tattctatca aaatgttagc gaggaggggt cataaattgt ataaagtaga
    91561 tttaaatagt gatttaggag aaagttttgg aacgtataag attggtttag atgaagaagt
    91621 tttaaaatat atttcatcag ccaatatagc ttgtgggttt catgcaggtg accctagtca
    91681 tatggaaaaa acagtacagc tagctaaaaa aaatggagtg aaaataggcg cacatccagg
    91741 tttcctagat ttaataggat ttggaagacg tgagatgaaa ataacaaagc aggaagctaa
    91801 agattataca aaatatcaac tgggtgcttt aatggcattt gcaagttcaa atggatgtaa
    91861 tatacaacat gtaaaaccac atggagcatt atacaatatg gcagctaaag ataaagagtt
    91921 agctatgggg atttgtgaag ctatatatga agtcgataaa gatattatac tgttggggct
    91981 atataatagt gaaatgataa attctgctaa agaaattgga cttaggtttg caaatgaagt
    92041 atttgcagat agagcttatg ataataatgg ttttttggtt ccaagaaatg tagaaggagc
    92101 agttatacat gatacaaaac atgcaataga tagggttgtt aggatggtaa aagaaggaac
    92161 tgtagaaact ttaacaggtg aagttataca tatcaaagca gattctatat gtgtacatgg
    92221 ggacaatcca aaagcaatag agtttgtcaa agaaataaga aagcgttttg aattagaagg
    92281 tatagaagtt tgtccattag aaaacataga agtttgttcg tcagagaaca tagtataaga
    92341 ctgataacat gagggggaga taaaatatga gtacaaaaaa tattacagat aaaactaaaa
    92401 ataaaaaaga tgtcggagca cttatagggg ctgcatttat aatggcaaca tcagcaattg
    92461 gaccagggtt tttaactcag actgcacaat ttacccaaga ttttggaccg aatttttcat
    92521 ttgtaatttt aattacaaca atccttttta taggggctca agtaaatgta tggagagtaa
    92581 ttggtgtatc aggacttaga ggtcaggata tagcaaataa aataatacct ggattaggct
    92641 atttagtagc ttttttagta gctcttggag gattagcttt taatatagga aatgttggtg
    92701 gagctgcact tggtatgaat gtaatgttta atatgaatat gacattagga actgtattaa
    92761 gtggattaat agctatattt gtatttatgt caaaaaattc aaattctcta gtcgataaga
    92821 taactaaatt tttagcatta ggaatgataa ttatagttgg atatgtagca atatcaaatc
    92881 atcctcctgt tggagaggca gtatcaagaa tggtaaaacc agaaaatcca aaaggactga
    92941 tattcccaat aataacttta cttggaggaa gtgttggagg ttatataact tttgctggag
    93001 gacatagatt aatagacggt ggaataacag gagaagaaaa tataaaagaa ataactaaat
    93061 cttctctttt gggtatatta gttgccacaa tgatgagagt tcttttattt ttagcaatac
    93121 tggcagtggt ttcaaaaggt cttcaacttg acccagaaaa tccagcagct tcagctttta
    93181 aatttagtgc aggagcaata ggatataaat tctttggact tgtattatgg tctgctgcaa
    93241 ttacatcagt tataggagct gcttatacat cagtttcttt cttaaagaca ctaaatcctt
    93301 ttatagataa atatgaaaaa tattttataa tagcatttat agcaatatca acacttataa
    93361 tggcatttat aggaaaacca gctactttat taattttagc aggagcttta aatggattga
    93421 tacttccaat cacattagga attatgctta tagcatctaa aagaaaagat attgttggag
    93481 attacaagca tcctacatgg cttttaatat ttggattaat agtagtttta atatctgcat
    93541 atacaggaat aacttctctt agcagcctag gtgctttatt tgcttaattt agaagaggtg
    93601 acatttatgg aaactagata cttgatatca ggggataagg cagtggttgc tgaatttgga
    93661 aatgagatat cagaagatat aaacaaaaaa gtaatttcat ttatgagagc aatagaaata
    93721 tcgaatctta aaggtattgt aacagaaatg gtaccaacat ataggtcact tatgataagt
    93781 tataatccat tagaaataga ttttgatagt ttgattgaga atttaaaaaa aatagaagat
    93841 aatttggaaa gtatagtatt accaaaacct aaaatacatg agattccagt atgttatgat
    93901 gaggtttttg gtatagatat taaaaacgtt gcaagctaca ataatctcac tgtagatgaa
    93961 gttataaaaa tacacacaag cagagagtac ttgatatata tgctagggtt tactcctgga
    94021 tttccatatc taggtggtat ggatgaaaga atagctacac ctagattaga agtgccaaga
    94081 actaaaattt atggtgggag tgttggaata gcaggttccc agactggtgt atatcctatt
    94141 gatagtcctg gtggatggca aataattggt aggacacctt taaaattata tgatgaaaat
    94201 agagaagaac agattttgct tagagctgga gactttataa aatttgttcc aataacatta
    94261 gatgaattta tagaaatcga aaaaaataac ttaagtattt aaatatcgtt atagtacagg
    94321 gagtggtata tatgggattc aaagttgaat taggaggttt ccaaacatta atacaagaca
    94381 gaggtagagt tggctatggt caatatggtg tatctggatg tggagcaatg gatgagtatg
    94441 cacatagagt aggaaatata ttagtaggaa attctgaaga tgaggcttct ttagaagttt
    94501 taatgttagg tcctacaatt acctttgatg aatatacgca aatagcagta actgggggag
    94561 atttaggggc taaaataaat ggaaaagaaa ttcaaaactg gaggtcatat caaataaatc
    94621 caggtgatgt attatcattt agaggtgtga aatcaggtac tagagcctat gtgtcaatag
    94681 ctggtggaat agatgttcca cttgcaatgg gaagtaagtc aacttataca agagctaaaa
    94741 ttggtggatt tgaaggtaga gcacttaaaa aaggcgatta tataaatact tttattcagg
    94801 aaaaagattt tacaataaat aaaaaattaa gttcaaaata tattccaact tatagttcag
    94861 aaatcgtact aagaattgta aaaggtcctc aatttgatgc tttttctaac ggtgaagtag
    94921 agaaattttt atcaaataaa tacaaagtta cgaatgaaat agatagaatg ggttgtagac
    94981 tagatggaga gagtataaag caccttaatg gagcagatat tatatctgag ggtatttctt
    95041 atggagctat acaagtacct ggtcatggaa aacctattat aatgttatca gatagacaga
    95101 ctagtggtgg ctatactaag atagggaacg ttataagtgt agatttgtat aagttagcac
    95161 aagcaaagcc aaatgatgta gtaaaatttg aacttgtaga tatatatgaa gcacatagac
    95221 tattgagaga gcaagaagat aagattcaag atatctacaa gagtatgaaa aatataagag
    95281 ttgtaaaggc aaaagtatta aatgatatag cagtttaatt ttaacaaata caatttttat
    95341 tatagtttat aatataactt acaaatagct atttactatt taccataatt aagatggttt
    95401 agattagtca aatagctatt tttttagttt gagtaaatat tttaaattta aataaatact
    95461 tcaattttaa aataaaagca atatttaaat ctattatatt atctacaaaa agtaggtgtg
    95521 tcatattgag tttatttaga ttttattggc caaattggag gtgatataac tccatatcca
    95581 cgagctattg tatctttact tggattgatg attttatgtg gtacattagc ttttataaat
    95641 gttgagtcac ctggatttaa tctaactacc ttttcaccca tacaaatatc aaccacacca
    95701 ctcgttacca ccataatttc ttctgatgca tgatatatat aatctttggc atcctcactt
    95761 tctggtttaa gttcaaactc tacaaataaa attgaaggtg taaactcagt tgtaggcatt
    95821 ggagatacta tctcgtaaaa catttcactc tttggaaatt tcatcataac tctatcttct
    95881 tttctaatga ctaaatcatc agtattattg tcatccataa acatatataa aggagtgtct
    95941 aaaacttcag cgatttttct caatgaagac aaggatggtt caatagcatc tctttctatt
    96001 tgagagatat aacttataga taaatctgtc aatttggaaa catcacttaa tgtttttttc
    96061 ttgctttttc ttatatttct catcttttca cctagcataa gaacctccaa ataataaaat
    96121 taatataaaa tattcgctta aaacaaagta attatagcac aacatagaag tagtggcaat
    96181 aagaatacat agtagatttt gacaattaaa atttaattaa atccaaataa aagtctatga
    96241 aaatgaatta ttgttaaatt aatacaaaga aaataataat aaaaaaattt aatagaagag
    96301 tattaattga attaagatta tcacattata ttttggaaaa gagtaaattt tcagtaaatt
    96361 atcttgacat atatattgaa gtaataatat aatttaaagt ataaaatttt aaaaattgaa
    96421 ttataacttc aaaaaataag gagggtaata tgaagataac agatatcaaa tttgaaaagc
    96481 ttagaattaa attaaaaaaa cctgtagtag tttcatttgg agtaattgaa tatggagaaa
    96541 gtataatttt aaaaattgaa actgatgaag ggtattgtgg atttggcgaa gcagcgcctc
    96601 ttgcagcagt tacaggtgaa gttttggata atgttctttc agtattgctt atgtttaaaa
    96661 aagagttaat aggcaaagac ccactagata ttgaaaccat acatacaatc atggatggaa
    96721 ttattatagg taatacttct gcaaaagcag ctattgacat agctttatat gatattaaag
    96781 gaaaaattat gaatgcaccc ctttataaag ttcttggagg atttgatagt aaagtccaaa
    96841 cggatattac tataagtata gataagccag aaaaaatggc agtagaagct ttagaaagag
    96901 taaaagaagg ttttaggata ttgaagctta aagcaggtat aaatcctgaa gacgatattg
    96961 aagctgtaaa gttaattaga gaagccgttg gagagagtat aagaattaga attgatgcaa
    97021 atcaaggatg gaacgtaaat agcagtataa atactatcaa aaagttagaa gaatttaatg
    97081 ttgatgcaat tgaacaagca cttccacatt gggatttaga tggtactgct tacataagaa
    97141 ataaaagtaa tacaaaaatt atgatagatg aatcattaca ttcaccaata gatgcaatta
    97201 aggctataaa aaagaatgca gttgatacat ttaatattaa gctgatgaaa tcaagtggaa
    97261 tatatcctgc tataaaaatc aacaacatag ctgaggcaag tggagtaaat tgtatgttag
    97321 gatgtatgct ggaaacgaga attggtataa cagcagcagc aaatttaata gcatctaaaa
    97381 agaacataac agaagctgac cttgatagtt ttatgttttg tgaagaatta gaaggtatat
    97441 ctggaggatt tgtaatggat ggagatatta tgaatcttgt caataaacca ggtttaggaa
    97501 tagaagtaaa cttatgataa atttggaggt taaatatgaa tacacttttt tcaaatccag
    97561 gtagtatact tgctgtaatg acatcaatga ttgcattggg tttttactta caaagataca
    97621 aagccattaa aagcttagga ccagcactta caataatcat aatgggaata atactttcaa
    97681 acttaaaagt agttccagta agtactgagt tatatggaac tatttcaaca tatgctattc
    97741 cagtttctat gactataatg ttgatgagtg ttgacttaaa agaaatgaca aaattatcaa
    97801 gagaaccttt aattgcaatt tttgtagctg tattaactgt aagtatcatg gcatttttat
    97861 ttggattagt atttgcagaa aaaatatcag aaggttggaa ggttgctgga atgtttgtag
    97921 gtacatatac tggtggaagt gctaatctta cagctattgg aacaggtctt aatgtaagta
    97981 gacaaactct tgctgcagca aatgcagcag actatgtaat tggagtacca acattgatat
    98041 ttatgtttgc tctaccagca atattaaaaa attcaaagaa gtttaaaaaa ctttggccat
    98101 atcatgtaga agaatcagaa ttagaggatt gtcaaaatga agaatttatg gagtcaaaag
    98161 aatggagtat taaagatata gcttggatgt tggctatagg ttttgttgtt acagaagttg
    98221 caacaatact tgctggatat ttcaattcga gttttagtag tgcagcaaga atacttttag
    98281 ttacaacaat ttcaattata attgctcaat taaagccagt aaagaaacta aagggaaatt
    98341 tagatttagg attatttgtt gcattattct ttttatgtac aataggtttt tcagtagata
    98401 taaaagaatt tttaggttca acttttacta taacacttta ctgttttagc ataatttttg
    98461 cttcatttgt tttccattta ggcataacta gacttttaaa gataaagtat caatatgtaa
    98521 tactttctat agtaggagca attgctgatg gtcctacttc agctttagta gctgcttctg
    98581 caaagtggaa ttcgcttgta agtgtagcag tcgtaatggg agtaattggt ggagtattag
    98641 gaaattatgc aggtatatca gtggcatatg caataaagat gtctctagga ttataggggg
    98701 gagtttaatt gataaaattt aaattataca tatctggact atacagtgga aatgtaatct
    98761 ttgatggaga tttattaatt gaaaagttga atccttttac aaataaaata gaaagtttaa
    98821 aaccaataag caaggaagaa aatacatact atttaaatct tacaaaaata gatttaaagt
    98881 ctttatttaa taattttgat gtatatacta aaagcttagt aaacacagat aaagacacag
    98941 ttataaataa cttaggagaa acgcattcta aacttaatga atatatatgg gttcaaagaa
    99001 acaaaaagtt cccactagat ataattattg tagataataa aatagtaggt tttatctgtt
    99061 tatccagaga aacttgtact atattaatta tggatggata tgaagagtat actgtattaa
    99121 aagaatggga aaaaactcat aaaaatgaag agatatattc tataagattt ggtggaaatt
    99181 atatgattga tatgaaagat ggtataaaac tttctacaga tgtatatctc cctgattttg
    99241 tagattctac caaaaaagca ccgacaattc ttatgagaac tccatatgga aaagaaaatg
    99301 ataaagaaat atattataaa tatgtacaaa gaggatatgc tgttgtaata caagatgtta
    99361 ggggaagaaa tgaatcagaa ggtaagtggg aacctatgat tcatgagagg gaagatggag
    99421 atagtaccat aaattggata gtatcacagg aatggtcaag tggaatagtt ggaatgcttg
    99481 gagcatcata tcttggttat gtccaatggg cagctgcatc ttcaggcaat aagcatctta
    99541 aagctttagt tagtatagta acatcaggaa gcccttttat tgatatacca agaaaaggag
    99601 gagcttttgt atctggtatg cttgcatggg catttatggt atcaagaaat aaagttgata
    99661 gaagcaaaat ggtaagagat gattgggatg atgttttaaa catacgacca atagaaaata
    99721 tacctgttga agctcttgga tatagaattg aatttctgga agaatggtta aagagagtag
    99781 aaaaagatga gtattgggat ttgatggatt ggcatttaca aaaagataaa ataaatgtac
    99841 ctgcattggt tgtatctggg tggtatgatg ataatagtat gggaactaca gaggccttag
    99901 atgttataaa ggactatgaa aaaggaaaga gaaaggctat tctaggtcca tggatgcata
    99961 attcaaatac tttaagagat ataaatggta tttctttagg aaatagttca ttaagatatg
   100021 atttggatta taattatcta ttatggtttg ataaatactt aaaaggtata gaaaataaca
   100081 tagatacgac tgctccagta gagtattact ctgtaggttc taataagtgg aagacagaag
   100141 aaaattggcc aataataaat aagatagata aaagtatgta tctaataagt gatggaaatg
   100201 ctaacacatc tttaggaaat ggtagattag tatttgataa tggtttagaa gaaaagtatg
   100261 atagttatat atataatcca aaagacccat cagtacaact aattgatatg tcagagaatg
   100321 aagttggagt tccaaataac tacaaagatt tagaaaaaag aagtgatatg ttgtgttata
   100381 catcagatgc ttttagtgaa gaatttactg taacaggtga tataaagtta gagttttttg
   100441 catcaagttc tgccaaagat actgactggg ttataaaaat tatggacgtg gatttagatg
   100501 gaaattcaat taaattagct gatggtatac ttagtgctag atttagaaat agtttttata
   100561 agtcagagtt tatggaagaa ggagagattt ataagtttac gattataact tcaaaaatat
   100621 caaacacgtt taaagttggt cataaaatta gactagatat aacgtctagt gctaaaaact
   100681 ttattttcca aaatagcaac acgacagagg gatataatag tattgaatat atagaagcaa
   100741 agaatacgat ttatcatgga ggtaaatatc catctaaatt gatattgcca atagagaata
   100801 agtaaattta tatagattaa atagtgagga ggtgtctcaa aatgaatttt ttagttcgtg
   100861 agacactttc ttttatacaa aatcaaatgt attttcatca tttcaacaat gaaaaagagg
   100921 cttatctctc tgttttgaga tagcctccta taagctaaat tgattatttt gtagctgcaa
   100981 caacgctcat ttcaactaac aaatgctctc tagcaagtct agcttcaaca caagctctag
   101041 caggttcaaa tcctttttca acccaagcat cccaaacaga gttcatagct tcaaagtctt
   101101 tcatatctct taaataaata gtaacagata gcaaatgttg cttatctgaa ccatatttgt
   101161 ttaataaatc ttctatttta gctaaaactt cagttgtttg ttcaattact cctccttcag
   101221 catgagtttg tccacataaa taaactgtat tgttatgaac tacagctcta ctcattcttc
   101281 cagttccttc atatctcttt atttccatat tttaaatacc tccatagtta aaaaatctat
   101341 taaaaatcta aataataaat taaaaaaagt ctatactata taaaattata ttatatattc
   101401 tgataataat ccataaaaac atataacttt ttagctataa ttattattgt tattaattga
   101461 aaagatttat tagttacttg acatagttta cacttttaat tatagtataa attggaatat
   101521 ttagataatt attatttaat gtataagcta agtttttaat taatatggtt ttatacattt
   101581 atatagaaaa gaggtacgta tgagtagcac aatcaaatca aatcgaataa aaggtataat
   101641 gtttataata gcatcagcgc ttggctttgc aatgatgtct gcattcgtaa agctagctgg
   101701 agatttacca agttttcaaa aagtgttctt tagaaatctg gtatcagcta taatagcttt
   101761 ttggcttatc ataaaacata aaggaagtct aactggtaaa aaagaaaatt taaaagtact
   101821 tttatatagg tcaatatttg gaactctagg agttatattt aactactatg caattgacaa
   101881 gttgatgctt tcagatgcta atatgctaaa taaaatgagt cccttccttg tagtaatatt
   101941 ttgtgcaatt gctctaaaag aaaaaataaa tgtaaagcag ataggagcta ttataattgc
   102001 atttatagga gctttattca taataaaacc aacatttagt gtagaaataa ttccatatct
   102061 tgggggaatt gcaggagctg tatttgcagc aatggcatat acttgtttaa gagttcttgg
   102121 agatagagaa gattactata caattgtatt tttcttttca gttttttcat tagttactgt
   102181 agggccaatt gcttttgcag tatatgaacc aatgaccctt atgcaactta tatatctatt
   102241 actaggggga gtatttgcaa gtctaggtca atttggaata actctagcat ataaatatgc
   102301 acctgctaag gaaatctcta tatttgacta tagtaatata atcttttcag caattttaag
   102361 tatattctta ttcaatgtct atccagatat gttaagtgtt gttggatatt taatagtatt
   102421 ttcggcagca ttttatatgt ttttatacaa taagaagtta gataaattag acaaagaaaa
   102481 gaagaagtaa actagataaa agtgttttta taatttgtat tgaatattta agtctttgta
   102541 ttaaaattaa agaaaattta attaaaaatg tttggtatat taacttataa cagcagttaa
   102601 aattgaaaaa ttataactgc tgtttctttt attaaaaata tccaaatgtc tgtaaaaata
   102661 gactataata gagtagtata aataatataa aggggataaa ttaaagtatg gaaaaagtga
   102721 aagttgctgt gattggagca ggtaatagag gaacgtatgc atatgctcca tatatttatg
   102781 aaaattctga tgtatgtgaa atagttgctg tagcagaacc taaaaaagga agacgagaac
   102841 tatttacaca aaaatataac ctagatagta aaaatgtatt tgaaacttta gaagactttt
   102901 ttaaacatga caagatggca gatgcagtaa taatagctac aaatgatgat agacattatg
   102961 atgtagcaaa actagctctt gaaaaaggtt atcatgtact attagaaaag ccaatgtcta
   103021 atagtttaga tggtctggta catatagatg acttgtgtga taagtataaa gataagattt
   103081 ttatgatttg ccatgtactg agatattctc cattttataa taaattaaaa gaaattgtag
   103141 aaagcaaaaa attaggagag ctagttagta tacaatataa tgaaaatata ggatattggc
   103201 attttgcaca tagctttact agagggaatt ggagaaatag caatgaaacc agccctttaa
   103261 ttttagcaaa gagttgtcat gacatggata ttttgttata tttagtagga agtagatgca
   103321 aaaaaatatc tgcatttgga agcttaaagc atcttaataa ccaaaatgct agtggagaga
   103381 tggcacaaaa ttgtcttcag tgtttagttg aaaaaaaatg tccatattca gcaaagagaa
   103441 tttatttaga aaaagataga agtataaata gagctgttca cataaatcca actgaagaga
   103501 atctattaaa tatacttaag acaagtccat atggaagatg tgtttacaga tgtgataata
   103561 atgttgtaga caatatggta aatatactac agtttgaaaa tggagtgacg gctactttta
   103621 atttatgtgc atttactaaa gaaaatggaa gaactataaa gttaatgttt agccatggtg
   103681 aagttggtgg ggatttaaat aaaaatgaga taagaattaa agaatttgga aaaaacgaag
   103741 aaatagttat gaatccatca aatcaacaga atatggtaga ggaatatgat agaaatctta
   103801 tagctgaatt tattaaatta gtttcaaata aagaactaga aaagggtaga gtagcagcaa
   103861 aagaagctat acaaagtcat gtaatggcat ttgcagcaga atattctagg gtcagtgatg
   103921 aagtagtgta tatagaagaa ttttttgata gtgctaagca aatgactaag gagatagaag
   103981 aaactatatt ttaattaata aaaatttatt aaataaaata aagatagatt aaataataga
   104041 aatacgaaaa tatgtgttct attaaggaat ctatcttttt tattaaggtt ttttcttatc
   104101 cctatcaaaa aaatccatac attctgataa aagataagaa agtaaagcga ataagatttc
   104161 tgtacttaaa ggaatcgtta ctgaatccat aaaggtatca attatgttca tagctagaaa
   104221 agttagtata aaatcaatta taaattcgca aagtttatat attgagtatg gtaatttgtt
   104281 tacatatctg aatatatcta aaatagtagt gcatagaaaa tcaattggag tggttataca
   104341 aaaatatatt aaaaagaaaa ttaatacagc tccaagagat ttatattcaa atcctaagaa
   104401 tgataagaag ccaattccta taaccgtgaa aatacaaaaa gttataccaa aaaaaacagc
   104461 aaaaaataaa aatacagaaa taaattcgcc taaaggaatc cttcttttat tacttatctt
   104521 aatcaactcc ttaatttatg atatgaaatt tatataaata ataacattct taaaaattca
   104581 taatagtcct ctgtttcaaa tagtactgtt tgagaatcta tttttttcat atttggataa
   104641 aaagaggcct taaaagcttt ataatgttct ctaaatttta tttctatctt aaatttatct
   104701 ggcaatttta ttaagtgcct agataaatct ccagataaag cttttttgac acctttttca
   104761 atttttttta gtgcaaggtt tggatggatt gaaattgaac catttccaat tccttttgac
   104821 acaggaacag tgactatatt tggatttagt ttttttgcac tctcacaaag catttcatct
   104881 ccacttaaaa atgctacagg aacattataa tatgcagcaa tataagcatt tatagtaaat
   104941 tcagatgcta tttcatcatt tattttaaaa tagtcataat caatatccat agtatgggaa
   105001 agtggattac cattacaagt agctccagag tgatagccgg tgaatataca tgcatcaaag
   105061 ctttcatcaa ttccagccat cataactagt gggtctttgg tccatcctct aagtattttg
   105121 acgttttcag gtaaaatatt tggattaata tttctaccac tgtcatgtgc atctttaaca
   105181 agtatttcat gtacaccaga ttgagtagct ccatcacatg ctgctgttat ctctttactc
   105241 atttgtgttc tatagtgttg cgaaaattca cattcaagtt ttgtttcatc ccaatttaca
   105301 ataccacaag taccttctat atcagcactt aaatacaatt tcataatata taccccctta
   105361 tgtttattat tgatgataat aacagataac agaaaataca taatcaataa agggcataaa
   105421 aatattatgt cttactatta attattatta aatctgtaac tgaaaaataa ctaaattggt
   105481 attaaaaaat ataacactat gtgtcattta tttatatagt ttttatatct gatgtttata
   105541 taaaattgta acatataagt ggttacattt actagtttaa catagttaaa atagttaggt
   105601 attattttta agttaaattg attattataa aatcgcagaa taaaagaaag atttaattta
   105661 ttaaaatgca tgaaatgttt tttcctcaac ataatgctaa attaaactca aaaagaaata
   105721 atagaaaaat cttatgtagc ttagaaagaa tgtgaatgat ttaagggaaa aatagaaatt
   105781 tattatataa tattaggctg tattatataa tacagcctaa tattatatgt atatgtgaca
   105841 taaaatcttg gtaagtgtaa ataaaataaa tgtggaaaac aagttaatga aatcaagaaa
   105901 aaagtaattt aaaattcaat ttcatcttcc caattaaatt ctcctgattt ttctacactc
   105961 ttaggccagt gactacacca tttaggaatg gacggatttt caaccctatc aacgcttgga
   106021 gtatatggct ttaagtctat aacaggacta ttatcattag catcaatata tggtattttt
   106081 attataccat tttcatggtc gatattgata atttgtacag cagtcaatgc tattggattg
   106141 ggtcttatag gtgaccttgt tgcaaatatt cctataacgt ctggtccact tttataaggt
   106201 tttggggttt ctaaaatact tcttagttca ggattatcaa acccatcagc ccaccaaaat
   106261 acatttaaat gactgaaatc gtcgagttca tttaatgcag gtacatactt tttgtctaat
   106321 ttaataaaga cctcttcgcc ttgaatacat attttaccta taggatttat taatatttct
   106381 ttcataatat tacctccaat tatttaattt atcatttgta attttagggt ataacatgac
   106441 atcatgtgag ggtcaatata aaataataaa taaaaatatt aatagttaga atgataatac
   106501 attttttaca tggagcatga caccagtaat aaggcaatct tcgtcaatat caaaagtaga
   106561 ggtatgcaaa ggggaagtaa tgtttttttc acgatttgca caaccaaggt ggtaaaaagc
   106621 tccttcacag tgtcttagaa aatacgaaaa gtcttcagcc ccaagagtgg gcgagtcttt
   106681 aaggataata ttttcttctc caaacaattc tacagcattt tgtttgacgt aatctactag
   106741 atggtttgaa ttgataagag ctggataacc ttcctcaatt tcaacagaaa tacttcctcc
   106801 aaatgtttta caagtaaaat cgcaaatttc tctaattcgt ttttttgaaa actctctagt
   106861 ttcaggagtc aaggttctca aagtacccct tataaccact ttatcacaaa ctatattttc
   106921 cttgattcca ccttcaatct ttcctagaga aataaccaca gaatcagttg gatttgtgtt
   106981 tcgactaacg attgtctgta gagctgtaat aatatgagca gatataacaa tagcatcaat
   107041 accttgatgt ggataagctc catgacattt tgaaccatgt acagttaatt gaagtgtatc
   107101 agtggaagca tttagagtgt tgtattttaa ttcaattaga tttttgttga tattggaatt
   107161 tacatgaagt ccaaatatat attttacatt tgggttttca agacatccat cttctatcat
   107221 aagttgagcc ccaccaatag tttcctcggc aggttgaaaa aagaatttta catttacatt
   107281 taagtaatcc tttaatttaa atagtatatt acaagtaccc agtaaaatag cagtgtgtgc
   107341 atcatgacca catgcatgca ttttgccaat attaatagat ttataagaat aattaagttc
   107401 ttctgttata ggtaaggcat ctatatcagc tcttatagca actgtttcaa agtttggact
   107461 cacgttaatg tatgcagtta tccctgtatg attcttatat tcaatataat ttatacctat
   107521 ttcatttaag tatttaataa tttttttctt agtttgaaat tcttctaatc caagttctgg
   107581 agtcttatgt aaatctcttc ttatatttat aacccaatca tttatctcat gacaaagagt
   107641 ttttatatta agcataaaac acatcctaac tatattaaaa atttattttt cttcattaat
   107701 tatattattt tatgtaaatc attattatgt atcaagtaca aataaaatat cttataatta
   107761 tattagagat atttagtatg gagaagaata tatcatttta taagaagagg tgtttaaatg
   107821 ttaggaataa ttgcgccatc tgggccatta agaaatacaa gtttggagga aataaagttt
   107881 aatttagaaa gttatggtta tgaagttaag ttttctgaaa gttgtagttt aaattataaa
   107941 ggttatttag ctggtaatga tgatattaga gcaagggata tagaagatat gtttttagat
   108001 aaagatgtag atataattat gtgcttaaga ggaggttatg gaacaacaag aatattggat
   108061 aaaataaatt atgatataat aaagcaaaat ccaaaaccat ttataggttt ttctgatata
   108121 acaggtttaa atttagcttt ctataaaaat tgtggtcttt taccatatca tggaataatg
   108181 gcagcaaatg taggtaaatg ggataaattt acctataaat cattggtaaa tgctttagaa
   108241 tttaaagatg aattatattt agaaaatcca aaagaagaaa agatttatac tgtatgtgaa
   108301 ggtaaagcag agggaataat aatgggagga aatttatcct taataattgc cacaatggga
   108361 acaaaatatg aaatagatgc aaaagataaa attttgttta ttgaggaaat tggagaacct
   108421 caatataaac tggatagaat gttaacacaa ctatattctt caggaaaact tgaggaatgt
   108481 aatggtataa tttttggaga ttttaaggat tgtattgaag aaaatgattt gatggaatta
   108541 ctaatagaat ttgcaaataa ggtcaataaa ccttctatat ataatcttca gtcaggacat
   108601 tgtatcccaa tgataactat tcctttgggc agaatgtgcg aattagatgc tacagaaaaa
   108661 atcgttaaat taaaaaaata gtgtgtatat aaatataata gaaatatggt ataatcttat
   108721 acaagtaaaa atttagctag gaggatgaaa aatgtctgat gatagaataa tagactttaa
   108781 cgaactaaag aacaaagtta aagattctga tgtagataaa tttgagcaat acatatataa
   108841 cttatatttt tctgttatgg atggaaagat gtctatggct gagttttcaa gaaaaatatt
   108901 cgattatatg agagataaca acatatctca agaaaaattt atgaaaatac aaaagcaatt
   108961 tatggagaga tatggtatgg acactgaaga agtagaaaaa caacttagaa actttggaat
   109021 cgacccttct acggcaggtt ttatgagtaa taatacttcc agcaaagtat ctacagaaga
   109081 tttagagtca tttaagaaga gtgcaggatt ttatgagaaa tatggagaaa aaatccaacc
   109141 aaagagttgt ataacaacat ttataaaaaa tgacttaaat gatattaatg taataatcga
   109201 ccaagaaaag ataatgcttt gtagtgatag aaaaataaat cttatggatt cagaactaaa
   109261 tgagttttta ttagaatata agaatatgtt taataaaaaa ataaaggtag taatgtgcga
   109321 aactacgaat aagtatgatt attaaaaaat gaatttaaat actgaagtag tatcaattaa
   109381 ttgtactact taaaaataaa aatcgcaatt tattattcct tataaatttg tataaggaat
   109441 atctaaactg cgatttttta tattgtgaag attagtaata atagatagtg ttttaaattg
   109501 taatcttctc actaaaactg tgtttttcta ttagaaattt tattaaaaat aaatatctga
   109561 taattgtatt atatgggatg taaagtatta gaagcttaac gaatctcttt taatacatta
   109621 actccatttt gaatcatact gttgaaaaat actaagttta aaatctcagc agggtgaacg
   109681 ttaggaatat cataagtatc tactaaattc ataggtacaa ctatattttt ttcaatatta
   109741 tgttgattaa aatatgattt tagagttatt gcaaattgat atatacatat atctgtgcaa
   109801 tcgccaacta taattatatt atctatatta tcaaaatcca aattttctaa tgcaaaaaaa
   109861 ccattagtag aatttttagg aagaatttgt aggttttcta tcgacttaag ttcatcaacc
   109921 aattcacttt ctacatcatt ttccaaacag tgaacaggat aactcaaaag ttctattgat
   109981 ttaggagtat gagaatcagt aaatgctatt actctattta atttgtttga tatttttttt
   110041 gtaaacattt caattggctt tattaaagac tctactctag gagagtataa tgcaccttgt
   110101 cttgcaaagc cattattaac atcaattata aataaagcag ttttactcaa atcataattt
   110161 tctatttttt ctattggtag attatctaaa ttactcttta aagcttcaag ttcatttaat
   110221 aagttatcca tagttatacc tccaagataa atttaataaa attgtacata ttaattatat
   110281 aaaagtcaag gagtacaaac tattgtataa ttagctgtat tgttttgagt gtaaaagatt
   110341 tgaagcaata tctggatagt tagtaaaaat accatctaca ttgagtttta gacagtgtag
   110401 tatatcatcc tcttcattta cagtatatac attgacacca agtagatttt tgtgacaaag
   110461 ttcaattaga gattcattta ctaaaactag aggtggatga agataactat tacccagaaa
   110521 tttagcaaaa ttgactacat tgtttatagg taaataacac aataatcctg tttttacact
   110581 agggtctaat ttatgaaagt tttttaagct attgctgttg aaactagata taagaactct
   110641 atttttcata ttatacttta aaataagctc taaaacgcct ttttctatat tgggatagtt
   110701 tattttgtca gtttttagtt cgatatttaa agtaaggtct gtaggtgaga ttagaattaa
   110761 tacttcttct aaagttggaa ttttacattc tttattgctt tgatatcctt caaaagatga
   110821 gtttagagtt tttaattttc ttaaagtaaa gtcttttaca aaaccatgtc cattaaaagt
   110881 tctatcaacc ttttcatcat gaataactac aatttttcca tccttagttc tgtggacatc
   110941 aagttctatt ccatatatat ccatatccaa acatttttta aaagctagaa tagtattttc
   111001 tggatacttt ccactaaacc ccctatgagc ataaatattc atttatatgg ttccctccta
   111061 taagtataac ttatcttata aaaatttaat taatataata tatcatattc caaaaggtat
   111121 tgttatatat tagttaaata actatttgta atttatatat tatataaatg tagaaaaata
   111181 aaatcatata tgtgttataa tatattttaa acattgtaaa tattacgaat ttagtagtca
   111241 taataagtgt aattttatgc aagctcatgt ttttagagct tgcatatgta ttattaatat
   111301 atttatatat tgtgaaaata aaattccaaa agaatttttt ctatagactt agtagtaagg
   111361 gggaattttg atatgtatga agttaattta gaacgagcta tgaattattg gatggatttg
   111421 ttagatgatt atacgaatat agcaaaaatt ccaaatgatt ttttttataa agattgttct
   111481 gatgaagtag tagatgaggt ttttaagatg aatattgaga aacatgaaag gttaattcaa
   111541 tattctaaag tgaacaatat tagcatagac tctatcatag aaactatata tggccttata
   111601 cttcaaaagt atatatatga agatgatgta gtttttggta aaacaatgaa tataattcca
   111661 ataagagtaa gagttagaca aagtgaaaaa tttatagatg ttgtaaggaa gctaaaaagg
   111721 cagtggagca ggtctttaga gtatggatac tatttgttat cagatataga gaataaaaat
   111781 catctaaata ctaagcttat aaacacaata tttatagcta aaagttttga tttatcatat
   111841 gattatgaca tagaaaaaaa aggatatgat ttatctgtaa tagtatatac taagagggca
   111901 cttaaaataa aaataaagta taaaccatct atatataaaa gagaaactat tagaagaatt
   111961 ttaaatcaat ttgattatat aatagagcaa ataatagaag ataatgatat tttaatagaa
   112021 gatttagaat ttgtatgtaa ggaagaagaa aaagtattat tggaagactt taataataat
   112081 caatatgaag taccctatga taaaagttat gttgatttat ttagggagca agttaaggta
   112141 acacctagta atatagctgc tagggatgaa aatagaaagt taacatataa agaattggat
   112201 gaagtaactg ataaacttgc aggttattta aatcatatag gagtggaaag tgaagacata
   112261 gtagctgtaa tgttaccaag agatattaac ataattatta cagcaatagg gattatgaaa
   112321 tcagggggag cattttttcc aatagacaca agtaatccag aagaaagatt gaattacctt
   112381 cttgaagata gtaatgcgaa agtagtgata actacagatg aactcaaaag taaggttgta
   112441 aatgagaata ccatagtact cgatataaat gatgaagaaa tgtttaagtt tggatatgaa
   112501 ttaactgaaa aaataacatc atcaaattgt gcatatacga tatctacttc agggtcaact
   112561 ggtaggccaa agaccatagc tatagaacat aagagtttag taaatatgtg ttattatagc
   112621 gtaaaatcta taagcgctac agaaaatgat atatgtggta tatacttaag tttcagtttt
   112681 gatgctgtaa tgaaacaact attcccttat ttgcttgtag gtgcatcaat agatattatg
   112741 cctgaagaag ctaaatttga tgaatataca gtaaatgaat actgtgagga aaatgacata
   112801 actatactag cattgccaac agcatttgca aggttattta tacaaaattg caataataat
   112861 tcacttagag ttgtacagac tggaggagaa agattaaaag gatatagaaa gcgtaattat
   112921 gaactatata atgagtatgg accaaccgaa tttactgttg tatcgacttc ttttcatgtg
   112981 gacagagaat atggaaaaat accaatagga aaacctatat ttaatactta tgcatatgta
   113041 ttagataaaa agaacaaact atgtccaatt ggagcaccag gagagctatg tctatcaggc
   113101 attcaaatat caagaggata tttaaataaa aaagggctaa cagagcaagt atttgtagag
   113161 aatccttaca aaacttgtga acataataag ttaatgtata gaactggtga tttagtaaga
   113221 tggttagatg atggaaattt agattatatt ggaaggatgg acaatcaagt aaaaattgat
   113281 gagtttagga tagagctata tgagattgaa aatataataa ataatattac agaaattaaa
   113341 agtgttgttt gtatatcgag aacaaatgat gatggagata tttatatatg tgcatattat
   113401 gtaattgatg aggaagatag tggtaagata aatgaaagaa ctattagaga atatttaaat
   113461 gagcatctac ctccatatat gattccaaca ataataatga ggatagataa gataccagtt
   113521 acaccaatcg gaaaagtaaa taaaagagca ttaccagaat aattttttta ttatgatagg
   113581 tgtcataaag tgatttcaga catttcttta tgacacttat ttttataaaa taatcaattt
   113641 gcataaaaac aagaattttc tgtatatatt tactatggtg aaaatttatt tataagaatg
   113701 attattgtat tttttatact tttccgtgtt ttaaagcatt ttttttacaa aattaatttt
   113761 acattaaaaa atttttttat tttatatctt aatagttttt agtagaattg aaaaataaaa
   113821 agaaaattag cataaaaata tctaaaagta gaaattaata atatagggtt aaattttagt
   113881 agttttgact cgctatttgt aaaataataa aaagttaagt tttatatgta tatatgttat
   113941 aatatataca aattgaaaag gggtgaaaat tttatgaaca aaaaattacc taagggtgct
   114001 tatggtgagg ttagtggaaa agattacgtt ccatatatca cagataagtc cagaaccggt
   114061 ggaaatgtag ctgtactgat tatcggtatt attttagctg ccatttttgc cgcatctaca
   114121 acttactctg gaatgaaagc cggtcttaca gttgccgcag gtattccagg agctataata
   114181 ggttctgctt ttgttggagc atttgctcgt tcaaagggta ttcttggtaa aaacttaatc
   114241 caaggtatgt caagtggtgg agaatctgtt gcaagtggat ttattttcgt attaccagca
   114301 gttatattaa ttggaagcca aattacattc ttagaaggct tagctgttgg agttggtgga
   114361 gttttatttg gtataggaat tgctgctata gttcacaact atctaatagt tgaagaacat
   114421 ggtaaactta tgtacccaga atcaatggct atatctgaga cacttgttgc ttcagaggct
   114481 ggtggagatt caattaagta catgggaatt ggatttgtaa taagtggatt tattactgta
   114541 ttaactggtt cattcttaaa tgtagcaaac aatgtaatga gtcttgtagg aagcaaattc
   114601 tacaaatgga aatttgatat tgaagtaaat cctctacttt taggaattgg atttatagta
   114661 gggcttgaag tttctttaac aatgtttgca ggaagtattt tatcaaactt tggtatagca
   114721 cctttaatag gatactttac agatatggct aaagatggag ctatggtatg gaataatcct
   114781 gcaatgcctc ttaaccaaat ggatgttgga gcaatatcta gtagttatgt aaaatatata
   114841 ggtgctggta tgatgctttg tggaggtatt attggtgcaa taaaacttat accaactata
   114901 atcgcttcta taaaagaaac acttaaagct aaatcaagtg ctggagaagg agaagaaggt
   114961 tcatctatac aaatgatact tttattaggt ggagtagtta ttggattttt agcagcattc
   115021 ttaatttctg gtaacattgt tatggcaatt attggagcta tcatatctct tttattatct
   115081 ttattatttg tcatagtagc tggtcgttta acaggaacaa tcggaacatc aaatcttcca
   115141 gtttctggta tgactatagc ttctctagtt attgtaacat tagtgtttgt tataatggga
   115201 tggactgatt tagaagctaa taaatcatta cttttatttg gttcatttat agttgttgct
   115261 attgctatag ctggaggtta tactcaatct caaaaagtaa cttatattat tggtggtagc
   115321 aaaaacgaaa tgcaacgtta ctttacaatt gcaagtatag ttggtgttat agttgttgta
   115381 ggagtaattt tattactttc tgaccaactt agagcaactg gtgataatgt acaatttgca
   115441 ttaccacaag caaacttaat gtcaacatta acttctggta ttatgtcagg tagtttacct
   115501 tgggttatga ttattgttgg agtatttatg gcaatagttc tatatgcatt aaatttacca
   115561 ataatgacta tagctatagg attctattta ccaattgcaa ctacttctat aatattagtt
   115621 ggagcattaa ttcgtttatt tgttgaatta gtatctaaaa ctgaaaaaga aaaagaagtt
   115681 aaagtttcta atggtataag tttatcttct ggtcttgttg ctggtggttc tatcattggt
   115741 ttaataggta taatattaca agtaactgga gttgtaactc caaaggtacc aagtggattt
   115801 gctgcaacaa attcaatggc aattgcttta ttagtagttt tagttgtgct tacagcatta
   115861 cctattgttt tatctaaagt aaaaaataat gagcaagagt aatgatgttt tagatattgt
   115921 atttaaaatt actgatggac ttgaatatga agtagctgaa aatcgtgttg ttactatact
   115981 tgaaaaacag gaccataaaa ttcaaaagtt ttttagaaag ttaaaagcta gaatacctaa
   116041 atacaaaaaa atagaactag atgaatattc cagttttgtt tttttacaaa ttgatggtca
   116101 aaggactgtt agagaaatag gcaagaacct agaagctaaa tatggagaag aatctcatcc
   116161 actttatgaa aggttgttag tatttttaaa tcatattgaa gttaattgtc actatattga
   116221 aagactggat atatagatat aataagaatt attatagata tattagagca tataaattag
   116281 aaggtaatta tgaaagaggc tgtctcaaaa tagagataag cctcttttgt attgttgaaa
   116341 tgatgaaaat atatttgatt tctcataaaa aagagtgtct cataaaacta aaaagttcat
   116401 tttgagacac ttcctttaaa atatttataa attacagatt taaagcaaaa cttattaaac
   116461 ttaagattat tttaatatta cttattatta gctatttcat cagctagatt atttaaatat
   116521 tcccatcttt catatttgta ttcaagttct ttttctagtt tagatttctc atctaaaatt
   116581 tcttggagtt tagtaaaatc agttgaaaat tttgcagtac tttcatcaag tgttgcaatt
   116641 ttagattcga gtttttctat atcagagtca atattttcaa actccctttg ttcattatat
   116701 gagaacttaa gctttttatc atttttaggt ttttcttttt ttggggtagt agagtcatct
   116761 tttttaactg attccctttt agattcttca aattcaattc cttgaatctc tctataaata
   116821 agataatcac tgtaattacc tgtatagata tgaatttttc cattaccttc atatgcaaat
   116881 attttattac aaattctatc taagaaatat ctatcatgtg atactgtaac tactacacct
   116941 ttaaattcgt ctaggtattc ttctaatatt ttaagcgttt caatatctaa atcatttgta
   117001 ggttcatcta aaagaagcac attaggagct gtcataagga ttttaagaag atgtagtctt
   117061 cttctttcac caccagataa tttacctatc aaagtatatt gcatagtacc attaaaaagg
   117121 aatctttcac acatttgaga agctgtaatc ctagtaccat ctgaagtttc tatatagtca
   117181 ctagcttctt ttacatagtc tatagccctc atatcaatat tcatatgaga gtcgtcttga
   117241 gaaaaacaac ctattttaac tgtttctcca attgaaatat atccactatc aggctctatt
   117301 tctccattaa gtatatttat aagggtagat ttacccatac catttttgcc tattatacca
   117361 attctatctg tacgagttaa agtgtattct aaattatcta taacagtatt ttcttcaaat
   117421 gatttagata tattgtgtat ttctattatt ttatttccaa gtctacttga tgcaacagat
   117481 atatcgagat tttcatcagg tttaaaagaa tctctattta taagttcatc aaatctttgt
   117541 aaacgagctt tttgtttagt gctacgagcc tgagctcctc gtcttaccca cgcaagctct
   117601 gttcttatta aattttgtct tttatcttca atacttgctt ctagcgaaag tctttccatt
   117661 ttcttttcca aaaatattga ataattccca tcataactga ataatctacc tttgtccagt
   117721 tcaataattc tatttgtaac acggtctaaa aagtatctat catgagttat cataagcaat
   117781 gaaccttttc tggaattaag atattcctca agccaatcta tagtatcatt gtctagatgg
   117841 tttgtaggct catctagtat caaaaactca caaggtgtaa taagggctga tgccagagag
   117901 actctctttc tttgcccacc agaaagttct gctatttttt gattaaagtc atttatacca
   117961 agctttgtaa gtactgactt agcttcactt tctaaatccc aaagatttaa ggcatctatt
   118021 ttttcgtgta ctgataataa ttttttattt aattcctctg taaagtttga attaagtttt
   118081 tctaggattt cttgatattc accaagtagc tttaattctt cagaagttcc attaaatact
   118141 tgttcaagta cagttgaatt ttcattgtaa gttggatttt gaggtagata ttctatccta
   118201 ataccattag tttttgttat attaccagtc tcactttctt caactcctgc aataattttg
   118261 agtaaggtag atttaccagt accatttaca ccaataaatc ctattttttc cccttcattt
   118321 attccaagag atatattttc tagtaatttt ttttcagaat agcttttact tatattttcc
   118381 aatgtcatta aattcatata attcaccttt atttctaatc tattattttt caaaatgttg
   118441 ataatctggg tttttccaat agccacccca actccaacct ctgcttacaa aagcattata
   118501 acaatcatca ccttttttta tcattccaaa ttttgtgcta gacctatcag cataaactgt
   118561 acttacttta ggtgtaacat catttccaga aacttgagga ttctgtaatg ggtttatatc
   118621 tatagcacgt cctttaccat gatttgaaac tacatttgta ccagctatag ttctataaca
   118681 aaatgatgag gtattattat cagacataga tttttcatct acagcatcat agtcatctat
   118741 taacttaatt ttttcaattg gatatttttt ttcgtataat tccttaaaaa tatccactac
   118801 ttctggagct agttcactgt ttactatcat ttctccttga tgagtttttt catcaaatcc
   118861 ataatatgta agttttaaat aagatagact atcaaagctt ataggttcat cagtaggcat
   118921 agatttacca atcattttat tttttatatt atctggtatt gaagaatatg aaaaagtagg
   118981 tttgatatta ttatcttcct gctttttggt agagctttga ttatttttag aatcatctgt
   119041 tgtattattt ttattttgca tagtttcttg actctttata ttaccttttt tgttgggatt
   119101 agagaacagt atctcatata tagataataa agcaagaaat aatacagtta ttacaatcgt
   119161 taattttaat ttattaattt ttcttcgttt tgacttttta ctcatattat cccccagtat
   119221 tagattcata taaactatat atattatacc tcataaaaat aaactaggct aacaatattt
   119281 agttaaccta gaacatttca tttatagttt ctccaattat ttttattcca atttcaatgt
   119341 cttcaaaaga caacctagaa aatccgagcc ttaaagtatc aaaaccagag ttatctgtaa
   119401 aaaataagtc tccaggcata aatataacat ttttttcata acatttttct aataaaactc
   119461 tagtatctat attttttagt tttataaata tatgcaaacc accatcaccc aagatatatt
   119521 ctgtttttat atattttttt atacatttat atgcaaagtt aaatttgtct ccatagaatt
   119581 tacgtatttt tttaatgtat ttttcaaaac ctccattact taaataatca aataaaattc
   119641 cttggtctaa aaaggataca tgtatgtttc tgcacctttt tacactttct agcttattga
   119701 ttactttttt atctgcaaat atccatccaa ttctcattcc aggaaataaa atttttgaaa
   119761 aactaccaat atatacgacc ccattattca tattatctag ggaacagata ggaaatatat
   119821 gagaactatt gtagagtaat tcttcattaa atccatcttc tataattgct atattgtatt
   119881 ttttcataag attatagaat ttgtacctat tttcaggagt cattacaatt cctgtaggat
   119941 tgtgataaga gggtgtaatg tatgcaaact ttattttatt tttatactta actaaattgt
   120001 cttctagcat attgaagtcc aaaccatctt catttatatc tacacctaag atattgaggt
   120061 tatgagattt cataattttt atagcagtat tatgagtagg attttcacat attatgtagt
   120121 ctttttcttg ggtaaaagat gacataataa tatcaaagcc ttctgtgaat ccatttgtta
   120181 ttagtatatc tttattactt atatcagcac ctttgtttgt catatattct agtaaatagt
   120241 caataagtgg cttataacct tgtgcatatc catagttgag taatttatgt ccttctagtg
   120301 aaattctatt taaaaaggat ttttttaatt cttccatgtc gaataaatct ccatctggag
   120361 aaatactttt aaaggaaatc aggtcagagc tccaaggaat ttcacttttt ataatgtcca
   120421 attcattggc ttttttagag tatgtattct ctaaacaatc ccagtttaat gaccatgtag
   120481 tatttgaaga cttattcttt gatttaacaa atgtaccttt tcctgaaata gagtagatta
   120541 atccttctga ttttaattct tcataagtta aaactacaga atttcggcta acttgtaaaa
   120601 gctgactaag ctcccttgta gaagggagct tactattgtc tggaattagt ccttttgata
   120661 tcatatcact tatataattt tttagttgta tataaattgg ttcattatca tttaatttta
   120721 gatttgaaaa tatcaaatta ccacctcaaa ttatttcatc taatttaaag agtattctat
   120781 aagtttatct aatagttcac tgtacttaat acctctagca gcagcacttc taggaattaa
   120841 actagtttga gtcattccag gaagagtatt tagttcaaga acatatggaa taccttcact
   120901 tataatcata tcaactctta catatgcttt gcaattaaaa attttccaac aagtctcaga
   120961 aatttcgttt actctttttt gaagttcttc atctaagtaa acaacttctt cctttgcacc
   121021 tttttcaact gagtatttag cttcataatc aaagaatcct gaatcagatt ttatagatat
   121081 tgtagggaac acttctccat ttaatatgaa tgaagtatat tctccacctg gtatatattt
   121141 ttcaatcatt acaaattcat caacttccag accttttcta actgcttctt caacttcatc
   121201 cttagaatga ataaagaatg tggctacact tgaacctcct gagtttggtt ttataaatac
   121261 tggataacct atattatcta tttcatcata gtctatttca tcaactgatt ttactaaaac
   121321 ccatggagca gtaggtaggt ttgaatctct aagcattttt ttagttatat ttttatccat
   121381 acacatccca ctgcaaagag gtccacatcc agagtatggt atatccatag tctcaagtat
   121441 tgattgtata catccatctt caccaaattt tccatgtaaa gcaagtattg caaaatctat
   121501 atcttctggt atctttgtaa atatatcttt tttatcatct attattacct ttacaacttc
   121561 atatttattt ttatcaaggt tattatatat ctcttttcct gaatttaaag aaacttctct
   121621 ctctgatgat attccaccca ttataactgc tattttcata ttatacactc ctattttaat
   121681 ttttattatt ttaaagtaaa ctttttattt acatacttaa ttatatgaat taacagttga
   121741 ggatgaaagt accactatat acgaagttta tattatgtgt ggttttagaa taataatcta
   121801 gtttaaagat atgtttaaat gattttttaa ctttatttat gttattattt ttgctaaaat
   121861 tattgttatg aacttaagac tagtcttaat ggctataaat caaggagtga taaattttga
   121921 aagctgaaat aataagtgta ggaacagaaa tattattggg agatatagta aatacaaatt
   121981 ctcaattttt agctaaagaa cttgcatcat tgggaataga agtataccat cagagtactg
   122041 ttggagataa caaacaaaga cttttagaat gttttgatga aagcttaaag agaagtgatt
   122101 ttgtaattac tacaggtggt cttgggccaa ctggtgatga tatgacaaaa gaaactgctg
   122161 cagaatactt tggtcagaaa ttagaactac ataaaccttc actagaggtt ttggaatctt
   122221 tctttgttaa aacagggaaa aaaatggccg aaaataatat gaaacaagtg tactttccaa
   122281 aagatgctat agtactaaaa aataataatg gtacagctcc aggggcaatt ttaaaaaaag
   122341 atggtaaatt tataatagta ttgcctggac ctccaagaga aatgaaagct atgtttaatg
   122401 agagtgtcaa accttactta caacaattca caaatgaaat gctagtatct aagactttaa
   122461 gattatatgg aataggtgag tcaaatctag aattagaaat tctcgatata attaatgagc
   122521 agactaatcc aacagttgct ttatatgcaa aagaattaga agttacaata agaataactg
   122581 caaaggctga aaatgaaaga gaagctttta aattaataaa accagtagaa gaaaaaataa
   122641 aaagtagagt tggtaaatat gtatatactg aaggagatat ttccatatct gaaggggaga
   122701 ctgctttaga agatgctgtt tctaagctac ttgtagaaaa aaatctaaca atagcagtgg
   122761 ctgaatcttg tactggaggt ttggtttctt catctcttat aaactatcca ggtatatcct
   122821 ctgtatttct tgaaggttgt gtaacatatt ctaatgattc taaaatgaaa agattaggag
   122881 taaaaagaga aactttggaa gagtttggag cagtaagtga gcaaacagct atagaaatgg
   122941 ctgagggcat tgctaaagga cttaaagcta atataggtat atctacaact ggagtagctg
   123001 gacctggtgg aggaaccaaa gagaagcctg tgggactggt ttatactgca atatatataa
   123061 atggaaaaac aatagtaaag aaaaatatat ttaatgggga tagaagaaag ataagattaa
   123121 gagctactag agatttgctt aatgaattga gaatacaatt agaaaagctt taagttattt
   123181 tgattaaagt attagtaaaa tataaaattg tttttggagg cttttaattt atgataaaac
   123241 atatattttg tgatttagat ggaactctat atgaaaatgg aaccataaca aaagaagata
   123301 tagtagcaat tgaagaaata gaaaaaaagg gagtacagtt taatgttgct acaggtagaa
   123361 tttttaaaca agcacataat attatcaaag atagtttaga tatgaatgga tactatgtat
   123421 gtgaaaatgg ttcatttata tatgataaag attataatgt aatttttaaa agaacgatag
   123481 atgataattt agtaaaaaaa gtcattgata gatttgagtc aagtgatgca caactttatt
   123541 ttaaatataa gggtgatgta attgtgggta gtgataccac tgcttttaga cattattcta
   123601 gtgactttat agttgaccca gattttgaaa aaagaagtag ttttgataat cttataggaa
   123661 atataggcgt atgttctgaa aatttggaag agttatccag aatagaactt tatctaaaaa
   123721 gtgagtttag tgaagtctta gaaatatatt tttctggaac atatacttta aatatagttc
   123781 ctaaaagtgt gtcaaaaaga ggaagtatag agcatgtaat aaaaacgtta aatgtaagtc
   123841 cagatgaagt tgctactatt ggggattctc caaatgatat ttgcatgtta gaaggattta
   123901 aatatagttt tgcaatgtct aaggcaaggg aagatgtaaa gcaaagtgca aattatgtag
   123961 tagatagtgt aaaaagtgcc atagatgtta taatggagat aaatagttag tataaaaaat
   124021 gactgtccta gagaagtata aaattatatt ctatagagca gtcattttaa ttatattcaa
   124081 ttataagttt atataagttt aaaaattctt aagttaaccg caatttgcta tatgatatga
   124141 ttttattgta ttagataaaa tagagtcaag tatataattt atgacactat tacaagtata
   124201 agctgaaaat tttaaatcat tcatataatc agttttcttt ttgtaatcac tataaagttt
   124261 agtaaaaaac ttctcaaaac tactatttat agtaccacat ttaattttag ataaatcaac
   124321 atcttttgca aatgctccaa gttctctttc ataagtaaca tgtttattta agctatgctt
   124381 aaattcccaa cgttcactgt gagctacaca gaaaaaatca cataaaaaat gacatatgac
   124441 tcctagttcc tgactaagtc tacttactga aaagtattta gaaagactat ctatattaag
   124501 actgcataga tagtttattt tagaaacaat catattaaat gactcatcta aataatgttt
   124561 ttttaattta tatttagaaa aagcatcagg ctttatattg ccatatataa aatttttttc
   124621 gcttataaag aatgttttat tttcatctat attatcaagt attgattttg ccataataaa
   124681 atgggtattc attaacatat ttacacctcg tatagtttat tagacttatt aaatatatta
   124741 ttatgatatg atatttatga taaaagttta atggtaaata tatgaaacta agtcaacagt
   124801 atttatttaa ataatttcaa ccatattcat aataacagta aatggccaaa tttacaatat
   124861 gtaaatagtg ttaagttttt atttatcaaa tttaaaatta agtattagta tactttctaa
   124921 ttaacctatt ggctttagac tgtgagattt caaggtgttt ggctacttta taagaactac
   124981 caaatttttc ataagcatcc aaaattatat ttttttcata ctctttaatt aaagtgtcaa
   125041 aatttttatt tttataatta gtagattttg agtcagatat aataacctta ttaatttggg
   125101 atatatgtgt tttatttcca ttattggtaa tatgtatatt ttttgtaaga atgtttggta
   125161 agtcatctat tgttatatga ttatctgtac aagtaagcaa gattttttga attatatttt
   125221 gtaattctct tatattgcct gggaatctat aatttgcaat agcatccata gcttccttag
   125281 aaatagtttt atttaggttg aagtcacttg agtacctatt aaaataatat tttataattt
   125341 ccactagatt atcccttctt tctctaagag gaggcaattt tatttctata acatttaatc
   125401 tatagtataa atcttctcta aacttttttt cttttacttt tgaaactaaa tcaacatttg
   125461 tagcagatat aattcttata tcgacctttt tattttttaa gctcccaact ggagtaaaag
   125521 ttctatcctg tattaattgc aaaaattttg cctgtagatt ttgtggtata tctcctattt
   125581 catctaaaaa aagagttcct ccattagcta attctacgag cccaacttta cctttagtac
   125641 ttgcacctgt aaaagcacct gaagtatatc caaaaagttc agattcaaga agttgtggag
   125701 atatagttgc acaatttatt gttataaatg ggccattaga tctattgctg ttgtggtgta
   125761 tatatctagc aagtgagctt tttcctgttc cagattcacc caataaaagt acacttacat
   125821 ccgttttaga aacatgattt actgtgttta tgattggtct cataactatt ccgtccataa
   125881 ttacagtatc ttcaattcta agtgcagttc tgtatagtgt ttctacttca gatttatatt
   125941 tttttacttg cttttttgtg tcttcaagtt tattttttat attattaagt tcagttatat
   126001 ctctacaatt ttcaacagta aattctaagt gtccattttc atcaaatata ggggtagcag
   126061 ttatgataag ctttttccct gtttgagtat cttgttccag tgaaaattta gtctttgttt
   126121 ttaatacaat tggtatgggg ctttttgttg aatatccaga gtcttctaaa aaagaaacat
   126181 tttttcccaa aatatcttct ttttttagac cataattttc ttcaaatgct ttattacaat
   126241 atattattat tcctttatca tcagaaacac atatttcatc atgggaagct tctaatattt
   126301 tttgataaaa ttccaaatct aaattcattt ttatattttc ctcctaaatt tttaatgata
   126361 tattaaaata ggtttaattg attaatatac ttaaaatttg atatttatat ataagtttca
   126421 gtctatttta actttaaata agttatatat aactcatttt acaattaaaa taagtctaaa
   126481 tcaacttaaa gtaagcgaaa aataaatata aaaaaattga aaatttatta gtattattgg
   126541 aaagactagg gttttagagt cgatatatat tgatttaaga tggcatagtt tttgcttaaa
   126601 aagaagagtg taaattgact aaataaaaat agaagggaat ttaaaatggg agaaaaaagt
   126661 aaagggtatg tatttatagc aatagcaggg ttattatggg ctacacttgg attatttgga
   126721 aagtttttaa tgggaaatgg actgacatca gaacaagtag catttacaag attgtttttt
   126781 ggatttatag ttttaggcgt atattcatct ataaggacac cacaaatctt aaagataaac
   126841 aaaaaaggaa ttatatattc agtaataata ggaattatat gtcaggcaat gtttaattta
   126901 tgttatttta aagcaattga cattgcgggt gtatcaattg cagcagtttt actatataca
   126961 tcaccactgt ttttagcaat attttcaaaa ttatgttata aagaaaatat tactagaagc
   127021 aaattatttt cacttattct ttgttttatt ggtgcaatta tggcagtgac tggtggacgt
   127081 ttggattttc aaggtttaaa cgcttttggg cttttacttg gagtattatc agcaatagca
   127141 tatgcactta tgccaactat tagtaaaaat gctttaaagg aattttcaag ttcaacaata
   127201 ttagtataca gtttcttatt tggagctata tttatgattc cttcttcaag accttgggaa
   127261 atcttaaatt atgctaagga tttagatgtt ttatcttgta tgctaatgtt aggcattgtt
   127321 ccagctgcac ttgcatatat tttttatgca gcaggtatat ctaaaggtgt agagttgtca
   127381 gttgcaggtg ttgtggcatc agtagaatta gttggttcag taataattgg ttgcactata
   127441 ttaggagaaa gtttttcctt agggaagtta tttggagtga tgttgatgtt aatatctgca
   127501 gtagtagcac ttaatctttc ttatgatgaa ataagaatat tttataagtc caacaagtta
   127561 aagcagattg aaaaaactga aagtatttag aattatatac ttaaaaagga tttattggta
   127621 tacattgtag attccaacaa aaattatacc aaattatatt tggtattaaa aaataactat
   127681 ttataaattt tatagaataa agtggacagt acaaataaaa tataagtaga tacagtttag
   127741 actatctatt ttttattata tattgtataa atgtacaaat taatattttg ttttgtaaat
   127801 actaaataac tatagaaagg actatatttg tataaccatt tctatagtta ttattttgta
   127861 ttaaacaaac ttacagccct gataagaatt tctagccttt aaagtatcat caattttatt
   127921 taaaatttcc cattttttta ggctccatat aggacctact agttcatccc tcttaccatc
   127981 accagtgagt ctatggatta tcatagtttc aggaagtatt tctaattggt cacagacaag
   128041 attgatatat tcatcttgtt ccataagagt taacatacca ttttgtaaca tcttttccat
   128101 aggagtatct tttataacat gcaatagatg gatttttata ccgtctacac ccattttacc
   128161 aactgccttt gctgtttcca tcatcatatt ataatcttca ccaggaagac catttataat
   128221 gtgtacgaca acctttatat ttttagactt taatttttca acaccttcaa caaatgtttt
   128281 ataatcatga cctctattta taattttaga tgtagaatca tgaattgttt gaagtccaag
   128341 ttcaacccat aaattggttc ttttatttag ttcagacaag tattctacaa catcatctgg
   128401 caaacagtca ggtcttgtgg atattgaaag acctatgaca tcttcaagtt ctaatatagt
   128461 ctcatatttt tcttttaaaa cttcaagagg agcatacgta tttgtatagg cttgaaagta
   128521 gccaatatac tttgcatgag gccatttttt taacatcatt tcttttatat tataaaattg
   128581 actgataaga ttatctttag ggtttccagc aaaatcacct gagccttctt tgctacaata
   128641 ggtacatccg ccataaccaa gacttccatc aatgtttggg caagtaaatc ctgcatttat
   128701 agatacctta aaaacttttt ctccaaaagt atttctaaga tagtaattcc aagtatgata
   128761 tcttttatta tcaaaagcat atttaaattt atccaaaaaa tcacctattt ctaataaaat
   128821 tgtacgctga gcttgtacaa aaaacatatt accacaaata gataacttaa acaaattcta
   128881 ttttaagtaa tataaaaata cagcgagaaa ataattaata ttttctcgct gtatttccag
   128941 agaaaaatag aactagtcca aataatatta tgaaaaaaga cattatcgat actataaatc
   129001 tagataaaaa aagtggagat aatataaggc atataccaaa tagaatctta actatattcc
   129061 aagttgtaaa tttagaataa ggattattct tactatttac aagtgctact agttgattaa
   129121 agattaaata aaatcctaaa aataatgaaa atatgctttg tattttttga ggaaatacaa
   129181 aaagtaatat acatgcaatt attagaaccc attggatatt aatagagggt ttaatttctt
   129241 ctttagtagc atatcttttt agttcattaa tattttttaa atttaaatat gcaaagaata
   129301 aaagtgcaat accaaaagtc caagaaatta attttatacc taatgtctta aatgtaaggc
   129361 ataataatcc taatataatg agtaatactc ccattaacat aaatttaatg gcattttctt
   129421 ttttattaaa gttattaaaa tcgatattaa aatttgtgta cataaaatca cctccaaaat
   129481 cgatagaaca attataacag aaattcatat ccaaataaag cctagtgtat aaaaattaaa
   129541 ctatacttag taattaatta ataggttgta tcataaactt ctattaatag aattatatag
   129601 aaggaggttt gtccatgaca aaattatggg caataatatt tgcattatta gcaggtggtt
   129661 ctacagctct tgaagctttt ataaatggag agctaggaaa aagtacaaca gcattagtgg
   129721 ccacctttat aagcttaact gtaggagcaa tatttttttt ggcaagtata atagttacag
   129781 gtgacttaaa gtgtctagta tctataaatg gttttaatta taagttgtta ttaggaggag
   129841 tatttggagg tctaataata tattttacag taaaggcaat tccaaattta ggagtatcaa
   129901 atacacttat attaactctt gtatcccaag ttttagttgg attttttatt gatagcgtaa
   129961 ttttgggaca agaaacaatg catttataca aatacatagg ggttatactt ttaatattag
   130021 ggacattctt tatagtgaat taacaattta atataatttg ctatgcaact caaaaatttg
   130081 gtataattat gttaataaaa caaagttaga tgaaagaggt gttaaaattg gctgatgaaa
   130141 aatttgtaat gtcatttagt ggtggtaagg atagtatatt agcattaaat cgaatgttga
   130201 aaaaaggata taagcctgtg gcactcttga caactataag tgaagaacat ggaaagtcat
   130261 ggacacataa tttagaatat aatatgctta agcaagtaag tagcaatata ggattacctt
   130321 tattagttgc tgagtgtggt gtagaaggat atgaagagag ctttgagagg gctttaataa
   130381 aagctaaaaa catgggagca actatatgtg catatggaga tatagatata gaaagtcata
   130441 gaaaatggga tactgataga tgtgaagcag ttggtatgaa agtagattta ccattatggc
   130501 aagagagtag agaggagtta gtatatgaat ttatagacag tggattttgt agtgttgtaa
   130561 caaaagtaaa cttaaagcac ttaggagagg aatttttagg aaaaaaatta actagagaac
   130621 ttgtggagaa gataaaaaat gctggtgcag acccatgtgg agaacatgga gagtatcata
   130681 catttgtcgt agatggtcca atatttaaaa aacctgtaga atatgaagta aaaggaactt
   130741 taataaaaga tggctatgga tatttagaaa taaaataatt acataaataa aatacctatt
   130801 atataatcct aatttttgca aaggtttaat atttgcaaga ttgtataata ggtatttttt
   130861 atttagatat tttcatatat tgtcactctt atcatctaag caaccttatt tagattagag
   130921 tctaatgtag aaaaattctt ttttagaaaa actaatgata aaataagaca tataaactca
   130981 gaaacaatag tagtcatcca tattccttgt ccaccaaata ttagtatcat tgaaattaga
   131041 cttaaaacaa ctattacaag ccctctacca agagatataa cagtagaaat tgatggtttt
   131101 tctactgata caaagaatcc agaaattatt acattaattc ctaccaataa gaaagatata
   131161 gagaatattt taaatacacg aactccttca ttgaatagca ttgtttcttc tggatgtata
   131221 aataaagaga ctattggtcc tgaaaaagcc atacaaattg caaatacagc aactgatgct
   131281 attattgtgg cttttatccc catttttaat aattttttta cattatctat atttcctgca
   131341 ccataataaa agctagtaag tggttgcata ccttgagtta tacccatcat agtcataagt
   131401 actaatgtat ttatataatt tatgacacta taataaataa gagcattttc tccaatatat
   131461 ttagtaagac ttaagttaaa aagtaaaaca actataccac aacttaattc agtagttgaa
   131521 tcaggaaaac ctataaatac aatttttcta agtgtcttaa aatcaattct aaattttgaa
   131581 aaattcaaag tagagttttt tcttaaaaaa tgtattaaga agaaaatagt agaaaagact
   131641 tgagacaaac cagttgcaat accagcacct tttacacccc atccaaattc aattacaaac
   131701 aagtaatcaa gtatgatgtt tgtaagagca gatattatta caccaacagt agctaatatt
   131761 ggaaagccat cagtttttat tataacttct aaagaataag acactataaa gaatccgtta
   131821 aaaaatatta ttattcctaa ataatcttta accataccaa ttgtagattc tgtagctcct
   131881 aaaaatagtg ctaatctatc taaattaaaa aaagttatag ctaatataat tattgataat
   131941 ataattattg atactaagtt aaatgaaaag acttcgttag cagatttaat atcttttttc
   132001 cccagataga ttgcaattat ggtagatgca ccagttgaaa ataatagaga aactgcaaat
   132061 ataaaattaa taaaaggcat tgatatattg acagcagcta aagctaattc tccaactcct
   132121 ttacttacaa atattccatc aaccattgta tatagtgaga aaacccacat tgcaactaca
   132181 gatggtgcta ggtatttaaa aaatctttta cctagactca tgttttcgtt tatagatatt
   132241 tttgtatcca tttactatca ctccctgtaa atctattata aaattacgaa actattaatt
   132301 aataatttta tttctaatat aaatgataaa ctatggtata ataccaatgt caacagcaaa
   132361 tagtatataa ttataaattt tattaaataa tagtgatttt aagggtctta taaatatatc
   132421 ttatttatat attactgaca tttaactgac aaataggaaa aaggtacttt aagtgacatt
   132481 taactgacaa atgaaaaaaa agcactttga gtgacattta attgacataa aactgaacat
   132541 tatttgaata gtattttgct tatattttca gatgtttctt tattcatttc atctaataag
   132601 tgagaatatg gaatatatat tcatagctat ttttatatct gcatgtacta atattttata
   132661 aatagctttt atgttagtac ctgaaagtaa tatcaaagtt gcatttgcat gtattaattc
   132721 atgtactttt atatctctag gattattatc tcttaatagt tttttaaaat gaacaacaaa
   132781 agttggttga actcacgggt tgaatctttt atttaagcat atcaaatcaa attcattttt
   132841 caatataccc tgtaatttta acttattttg ttttaatttt tcccctttaa gcaaacttat
   132901 aagttcatca ggagcaaata attttctttt tgatataggg gttttagggt ctttgaagat
   132961 tattttattg tatacataaa ctaatgtttg atttacatgt gagatttttt atcaaggtct
   133021 acatctgacc atataagtga tacagcttca ccaaaacgta atccaagagt tagcatcaaa
   133081 aaaattggta tacctatagg aatatttttt gatttttcta ataataattg agctttttgt
   133141 tttgtataaa gcttagaagt tgaactactt ttttgattgg ggttgtaaca aaatcacaaa
   133201 tattttctga tatttctttt aatctataag attctttcaa tactgatttt ataaaatcga
   133261 cttggttttt tattgaattt aacatgtgct cattgtatat gttatttata taagactgta
   133321 aaatagaagg tgttatatct attaatttca tatctttaaa gaaaacttca atttgatttt
   133381 taatcatatt ttttctattt ctaatagtat taggagaaaa actacattct ctatctttta
   133441 tatatctgta acatctttct acaagtgtta cattatttgg agcaacaaac ttattattgt
   133501 ttatagtgga ctattggaaa atcgaataat aataacttgg tattcgaaac ttttgataaa
   133561 acaatagaac tatatccaaa tgcaaaacct atttttcata gtgatatagg atttagatta
   133621 gatgatgaaa gttttgaaga gtatttagga agagtattta gaaagagatg caaagggata
   133681 taagattgta aataaaaatg gattttttaa tgaatttgat ttttatgaag cagtaaatat
   133741 atgtttaaat atctcaatag aagatgcgat aaaatcatat aatatattag ttaaatcatt
   133801 agtaatgtta gataaaagat taggtaaaag gcgattaaaa aatatatatg aagatataga
   133861 aaaagagaat aatttagtaa agaaatttta taatataaga gttgaatcag aaaatatgat
   133921 tttaaagaaa aatgcataaa aaatacaact aatacagaaa taaataaagt aaagttccat
   133981 ggaaaactga gaaatttaaa aagagtatat atattgaaat gtagtaattt caatatatac
   134041 actctttttt attttgaact aattcctaaa cgtcaattta gagagtaatt gaattttaag
   134101 tttagttaaa atgaaagtta tttttactaa atattatctt tgttgtatag ttttatttat
   134161 aatataaaaa aagtaactct atgctaggat ttatgactag aattagaata aaagttctag
   134221 cttataatat ttcatttttt ataagtaaag ttatgagcaa agatgaatct atagcaaaaa
   134281 ttaaagagtt aatatttgga tgacttatcc ataaactaac ccttaggggt gatttgtttt
   134341 actaaaatca atttacttta tatgggaatt aaactttaac tagcacaata gactaaataa
   134401 tcatgaagta ttcgattcga aatacgttga ccatattaga tttttctaaa ttttctacaa
   134461 atatatatta aaaatatttc taataatata ttcgagaaca taatacaatt ggcaaatatt
   134521 atatatgaac tctcactttc aaatagctga tattgccaat tagaccttaa taattcatca
   134581 atatactcaa cgaataatct ggataataca aaagcaataa ttacagaaaa tatacctata
   134641 attaccattt taatactaat ctttattttt ttttgattca tttattctcc accctctctc
   134701 tttactttgt ttctacaata taacaattat gaccttatga ttttataata ttttatttat
   134761 aattttgtca tttttgtatt ttctttactt gttcatatca ttattatata tgattttctc
   134821 acagatttaa aagtattata atccacttgt agctaagaaa agaactctaa ataattagtg
   134881 ttcttttctt atcgacttat gaatcagttg gcaacatgaa atatttcaac gacacgtcgc
   134941 ttaagcgaag taaatttttt atttattatc gttacatagc atttgtaatt agttttataa
   135001 tttagttaaa aactttgaga tgtgtcttta gattatctaa agtatttttt aatattttag
   135061 atgtattaat tttatttttc tctaaaaagt gtactaatct gtattttctt tgcttttcta
   135121 agtgcattaa atgaagaaat atatattata aaatatatat ttcttaatgg tgttagatat
   135181 acatatatta tacaagagtt ggtcgttgcc ttgacaatgc tcctatggaa ggattttggg
   135241 gaattttaaa ggtagaaatg tactatttaa ggaaatttga tacatatgaa taattagtta
   135301 aagcaataga tgattatata tactactata ataattttag atatcaaaat agattaaatt
   135361 ctatgtctcc atttgaattt aggaaatatt taagtacaga gagagcataa tttattttaa
   135421 gtatctctaa aaaaattaaa tatctagggt tttatttgac gtgctctttt ttagatagta
   135481 agctttaaaa tatagatatt aattatatga atataataaa aagagtacta atgagttaca
   135541 ctagtacttt ataactattt ttacatgttt taactgtata aaacagcggg tatagttcac
   135601 acaggcagga gtgactttag ttttgaacta aaaatcaagt tcaaaaagaa taaacattag
   135661 tatttgaact tcactctacg tctaaataga ttgtagttct tcttgctttt attataccac
   135721 aaattggtat agatattcaa aaataatata tttatgatat aataaaaatg taaatagttt
   135781 tgcagtgagc gatatttgtt acaaagtaga gcttaacgct tgaaatataa ggtgttgagg
   135841 gtatatgata agctttatca tttgcactac tcatggttca ctgcaaattt aagagagttg
   135901 catatgtgta agtattgaaa atgcccagtt tatttggggg ttttatatta actaagtggt
   135961 atgtaaatag agagataagg caaataatct gtaacaactc caaagtttta tattaactaa
   136021 gtggtatgta aattctgaat acggaacata aatagcaaca gtaccagaat gttttatatt
   136081 agctaagtgg tatgtaaata atgatttatt aaaaattttt atttgttttg atattgtttt
   136141 atattaacta agtggtatgt aaatagagta aaacaatagt acaagaacaa ataaatacat
   136201 gttttatatt aactaagtgg tatgtaaata ctttctgtag ctctatagat aaataaggtg
   136261 ctaaagtttt atattaacta agtggtatgt aaattaactt tataaaaccc agtaattgca
   136321 acacttttat agttttatat taactaagtg gtatataaat agtataatgt tgaaaagtta
   136381 gagagtacaa tcaagaaatt ttacattaac taaaatgtat agaataaaac atgtatttat
   136441 acttaaattc tgtacctata taaaaaagtg aactctgtca acaaagcact tttttatata
   136501 gataaattat cattttgttt taagatagaa gatactaatg ataactgttt atcattagta
   136561 tctgtatgta tataaaagtt taatttttta tataaatttg ctctttagaa aaatgagcag
   136621 tatcaataaa tatattgttt aaattttttc taggaactag ttgactagct ataagattag
   136681 cttcaactct ttgattgtta gactatgaaa ttaaatttaa aggttcattc ttggtcgtat
   136741 aaatagcttt attattcgta tgtactataa caatttttgc catctgcttt tgatagataa
   136801 agagctttat cagctttaga aaataaatct ttatataatt tagttgaatc atcagtgaag
   136861 gcaataccaa tacttaatgt tattttatga ttgtccttta cttttatttt actcgcatca
   136921 tttaaaatat cattagtaat ttttattatt aaatcctttg ttaatgattt tataaatatt
   136981 gtaaattcat ctccaccaat tcgagcaact atgtctttat catgtgtgtt atgtaatagt
   137041 atttttgata cagcaactaa aacttcattt ccctctagat gcccaaaagt atcatttaca
   137101 gttttaaaat catcaatatc aataactaat agagcatcat tatttttgga atcagaacta
   137161 catagatact cttcaataag attttgtgat actctttgat tatataattg tgttagtggg
   137221 tcacgttgag cctgattaat taaactttct aatttagatt tatcttcagt tatgtctttt
   137281 aaaacgccta ttgttttgat aggattatgg tcactatcat atataactga acattgaaca
   137341 cgaatccatc tccattcatt tttagttaat gaatttactt gtcttatctc aattgtttca
   137401 cgaagatttc catgaagtac ttctagtagt tttccaatat catcaaggtg aataatttta
   137461 ccagattcta atagtttgga gtaatttttt gtttcaaaat tttctaattc aatttttttg
   137521 tcaatttcta cacgttgata ttttataagg gtatcgtttt caatatcata ctcaaacatg
   137581 atatctgtaa tattttgcaa agcaatacga tatcgctctc tttctaattt tagttcagat
   137641 tctatgtttt ttagttgggt tatgtcagta ataatactat taatttttac tatgccatca
   137701 ctatttaacg atttcattcc agaatctaat acccacatta atgttccatc tttttttcgg
   137761 attctatatt cagatgaata tgtaggtcct tttgcaaaac atcgttcaca atcttctagt
   137821 gctttaggta agtctggtgg atatacagca cccactgctg aaccaccact catttccatg
   137881 aactcatcat atgtgtatcc taatattttg ggcaatccct cattgacata gaaaaatgag
   137941 tatgtactat catcattgct accttttaag ccaccattga tattatttgt aatcatttca
   138001 ataacttctg ttttttcttt tagtaatctt tgcaaataat cataactttg agttccaatt
   138061 ttagtgggaa agtattcatc aagttgcatt tcaccataag ggtttgatat gtgcatgtgc
   138121 tttattaata attttcctct atcctcaatt atctcaaatg tacaacgttg atttacctct
   138181 aaaatcattt gagcattttc tttagttcga acagtatatc ttcctaatac catacatcta
   138241 ttctcatctt cacttacagt ttcaaatata tcattattta tatcacaaga aggaatttca
   138301 tcttgacctg cataaaaata attttttatt tcattaaaag aagtgagaaa ttcctgttct
   138361 cctggtccaa tccatgtaac attttcacaa aggtatttta atacttcatt gatatctcga
   138421 tttatataaa aacttgttat aatatgtttt gctaatttgg gtgctttttt taggagtatg
   138481 ctcatgatat tcctcctttc tttttgctat tatattttaa ttatattata catcaatata
   138541 tttaaattaa aagctttgtt aaactatgat atctttgtta aataagttaa ttttaacaaa
   138601 aaagaactga aacaatatat gcttcagtac ttaatgtcaa tatcttgtat agatacatat
   138661 ttataaacta atgtacaagt ttaaaaaaag aaagataatt ttaatttatt ttaaaataac
   138721 aatgttaata atcattttta tcaaattttt tcttgttttt ctccttgttt ttatacattt
   138781 ttttatccaa ttcaactatt gtcaatttta aatttctttt tactgtatca acaccataac
   138841 taaatgaaag atacttatac ttagagaata cttttaaaaa attttctctt aaggcttcta
   138901 gctgtgaata aacataattt ttgtcaacat cactagagaa tataacaata aattcatctc
   138961 ctcctaatcg tataatagaa gtagaattta ttaattcttt atttaaaagt gaaacaaaat
   139021 cacataaaat cttgtctcct acattatgac cttcatagtc atttatcatt ttgaaattat
   139081 ctaagtcaat tagtacaata taatctccta taaatatgtc aaatctatca tttaaatatt
   139141 ttctattata tgctccagtt aatgggtcag taattgagta gtgaagattt ctcttatttt
   139201 cttcatagag ttttgttata tcattggcca tagtaattat gtaggttttt tcatcaacat
   139261 ctactttgta ttctaaaaca ttccaatagc ttgtagtatc ttttttaaac tctaaaatcc
   139321 aatttgaaat tttatcataa ggataatttt tttcccaatc taattgaata ttgtgagaat
   139381 ccgtaaaaaa tttagcaata ttatcaggga gtttcttagc tatttctata ttagtcattc
   139441 caagtggatt atcttgcata taacttttaa ttaaattttt taaattatca tttataaata
   139501 taattctgta gttagaatct cttataatta gaaatcctgg aaaagttctt aaaaaaattt
   139561 ctttaaacat attaatttct ccaaaataaa atactttgta ctagattttt gttaaatttt
   139621 ttattttatt tacatctaca tacataccct gggcaatcga ccttccatca attgcagaaa
   139681 ggttacattg tgtatacata actgtgacaa tttgaccatc tcgttttatg aatctatata
   139741 aaaatggttc aattttattt gtgtcaatca tgtccaaact ttttttataa acaaagtcta
   139801 aatcatctgg atgaacaatt gctcttaaat ttccgcccat ctcaccaaaa aactgttctt
   139861 ttgtataacc tataatatca aacatttctt cattcatata agtaataatc atatcaccaa
   139921 ataaatcgta gcgaattata cctacaggca acattgaata aaattgtgat aaaatattac
   139981 tttcatcaag atgtgtattt gtcattttag gtattgaata tgattcaaat tcatttatat
   140041 agccagcagt tttaattaaa tccaaatgta attttgctaa gagtaattta ttttctgaaa
   140101 ttatacaatt tgcactaaag tagaaattgc tatatttttg atgttcagaa gcttcatctg
   140161 ataaaacggc ttctccacta attaataatg aatctgattc agtattatgt ggggttatac
   140221 ttttgtaaag aatagaaaat tttttacctt taatatgttt ttcaaaatgc tctattactt
   140281 taggaaaaga tgtaatttca gttttgttgt aaaaatcaaa ccattgaatg tcttcagtga
   140341 cattagctct tagttttttc atatcttgca taataaaaaa tccatcaaat atcttctcta
   140401 ttaaagattt tcctatatca gaatatttta taaacatttt ctctgaatta ttctctttag
   140461 atagtaattt ttcaaattct ttgcactcca tgggttttgc ataataataa ccttgggcga
   140521 tatcacaatt tatactttta ataaattcta catgttgttc tgtttcaaca ccttcacata
   140581 ctgtaagcat cccaagagct cttgcaatgt ttattataga gtacaaaatg gttgtatttt
   140641 taaaatcatt taaattatga gataaaaata tcctatcaat tttgattata tcaaaaggta
   140701 gattttgcaa cataccaaaa gatgaatatc cagaaccaaa atcgtccatt gatacagaaa
   140761 aaccataaga acgaagttca gctagttgtt gaataattgt atttgtattt tctattaata
   140821 tattttctgt tatttcaatg ctaaaatttg atgtagagac gctgtacttt tcagtaatac
   140881 cttttagcat acttggaaaa ttagggttaa aaaaatgaag acgagaaaag ttacaacaaa
   140941 ttggaacaaa aacatcattg ttatcaatcc atcttcttat atttttacag ttctcttcaa
   141001 ataaatgcaa atctaattcc gttatcagac caaactgttc aaataaagga ataaatttat
   141061 ctggagtaag aagtccttta atagggtgtc tccatcttgc aagtgcctca catccaacta
   141121 tagtattatt ttttatatta taaagtggtt ggtaaaatac ttcaatttgt ttagtttgta
   141181 gaacatgtga tatttctgat aagaactcct tatcattttc taatttattg taaaaactat
   141241 tatctttaaa atcaaataga atgtatctat ttttaccttc acttttagcc ttttttaaag
   141301 cactatacac ttggttgaaa agcatcaaag tagtcatgtt tggttcacca ttccagatag
   141361 tgctgccgat actaaatgta acattggagt atatttcttt ttcattagga agtcttattt
   141421 ttaattctcg ggcgctctct ataatagttg cacccatatt atttaactct ttatttgata
   141481 catttggaag tacaattaaa aaaccttctc cttttaaata agcgactatt ccctttgatt
   141541 ctggaataaa gtgcaatagg ttttgagtta gagtaattaa taaattttct ccgactaggt
   141601 atccatatat atcattaaat aatttaaagt tatcgatatt taataacatg attcctatat
   141661 gtatattttt cgaaatacag tcatcaatat gttggtacat aaattctctg tttggtattt
   141721 tagaaaaaaa atctatttca tttaaggttt ttaatttaaa atttctacta tctaattcct
   141781 tagataatac ttctaccttt ttatttaaca tttttatata attatgattt tgcatggtat
   141841 tcctccataa gatactttaa attttgatga caactgtatt tatgctagaa gtatttaaat
   141901 gttaatttgt aaataattta aatgctaaat tttaaataag tatttaaaat gaatatacat
   141961 taagttattt gctccaatgc tacaaataca aatatttttt agtttagtaa taatattaga
   142021 taaaattagt taatgcttaa attctagtat attgaaagat ttcctttttg aatgcaatta
   142081 tatcatattt tttcataaat agatagattg tgagctgtat agttagtaag gtagagtttt
   142141 tttataatta attttaagtt taatgatttt tcaaaggcat aattatttta ttcataatta
   142201 actttttata cataatttaa taccatatta ataattttgc ataattaatt ttagttatta
   142261 aaattaagtt tattctt
//
LOCUS       DAEHWO010000002       127679 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEHWO010000002 DAEHWO010000000
VERSION     DAEHWO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 127679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 127679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..127679
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.002"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            8..283
                     /locus_tag="KNP54_000127"
     CDS             8..283
                     /locus_tag="KNP54_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891064.1"
                     /translation="MTLLELYYRKAEINKIVWARIGFNLYLSKGVALTLTDAGIGISG
                     LLAGAIPGIGQYLPLIVRLITMYLESNITSGKIFKFKKYVIIKEVLV"
     gene            complement(295..468)
                     /locus_tag="KNP54_000128"
     CDS             complement(295..468)
                     /locus_tag="KNP54_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891065.1"
                     /translation="MNDATKVSIKNETNNIMNLCNLLSWNALLQNNKINAETIAKSRY
                     FIIILSPIDFYRL"
     gene            631..948
                     /locus_tag="KNP54_000129"
     CDS             631..948
                     /locus_tag="KNP54_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891066.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
     gene            complement(1933..2148)
                     /locus_tag="KNP54_000130"
     CDS             complement(1933..2148)
                     /locus_tag="KNP54_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891067.1"
                     /translation="MHINQTGFISNELGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVRGGSSWAFNFIVQP"
     gene            complement(2331..2675)
                     /locus_tag="KNP54_000131"
     CDS             complement(2331..2675)
                     /locus_tag="KNP54_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891068.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVFLILIQ"
     gene            2802..3185
                     /locus_tag="KNP54_000132"
     CDS             2802..3185
                     /locus_tag="KNP54_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891069.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            complement(4395..4646)
                     /locus_tag="KNP54_000133"
     CDS             complement(4395..4646)
                     /locus_tag="KNP54_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891070.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(4892..5047)
                     /locus_tag="KNP54_000134"
     CDS             complement(4892..5047)
                     /locus_tag="KNP54_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HBF0891071.1"
                     /translation="MALDVKIEVKIIKDVVILNITHWKKETSLLTVKIARSQGDLSYV
                     KYFANES"
     gene            5758..5982
                     /locus_tag="KNP54_000135"
     CDS             5758..5982
                     /locus_tag="KNP54_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891072.1"
                     /translation="MDVNQRIKYIRENMNSSQKELLEKTNINTSVMNRIESGERPTRD
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     repeat_region   6269..6495
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=6334..6362
                     /rpt_unit_seq="ctttacataccacttagttaatataaaac"
     gene            complement(7149..7301)
                     /locus_tag="KNP54_000136"
     CDS             complement(7149..7301)
                     /locus_tag="KNP54_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891073.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
     gene            complement(7451..8878)
                     /locus_tag="KNP54_000137"
     CDS             complement(7451..8878)
                     /locus_tag="KNP54_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HBF0891074.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISVNALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKIVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTVAKNNAIVLVDNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKVYN"
     gene            9069..9890
                     /locus_tag="KNP54_000138"
     CDS             9069..9890
                     /locus_tag="KNP54_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBF0891075.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            10015..11532
                     /locus_tag="KNP54_000139"
     CDS             10015..11532
                     /locus_tag="KNP54_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBF0891076.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKAYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            11555..11839
                     /locus_tag="KNP54_000140"
     CDS             11555..11839
                     /locus_tag="KNP54_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0891077.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(11936..13606)
                     /locus_tag="KNP54_000141"
     CDS             complement(11936..13606)
                     /locus_tag="KNP54_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBF0891078.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDIDKSMKKELEKNGIMVEEKTMRYAKDGL
                     LSHTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKT
                     VDNKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQND
                     ISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNT
                     NEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGL
                     DEEKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNM
                     NTIKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLN
                     KKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(13678..14925)
                     /locus_tag="KNP54_000142"
     CDS             complement(13678..14925)
                     /locus_tag="KNP54_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBF0891079.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEIYEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            complement(14912..15586)
                     /locus_tag="KNP54_000143"
     CDS             complement(14912..15586)
                     /locus_tag="KNP54_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBF0891080.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRKYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            complement(15758..16837)
                     /gene="mltG"
                     /locus_tag="KNP54_000144"
     CDS             complement(15758..16837)
                     /gene="mltG"
                     /locus_tag="KNP54_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBF0891081.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFSYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            complement(17050..18375)
                     /locus_tag="KNP54_000145"
     CDS             complement(17050..18375)
                     /locus_tag="KNP54_000145"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBF0891082.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            complement(18579..19391)
                     /locus_tag="KNP54_000146"
     CDS             complement(18579..19391)
                     /locus_tag="KNP54_000146"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBF0891083.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            complement(19438..20610)
                     /locus_tag="KNP54_000147"
     CDS             complement(19438..20610)
                     /locus_tag="KNP54_000147"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBF0891084.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIEGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            complement(20652..21566)
                     /locus_tag="KNP54_000148"
     CDS             complement(20652..21566)
                     /locus_tag="KNP54_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0891085.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAAEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            complement(21578..22183)
                     /locus_tag="KNP54_000149"
     CDS             complement(21578..22183)
                     /locus_tag="KNP54_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBF0891086.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKSR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            complement(22251..22787)
                     /locus_tag="KNP54_000150"
     CDS             complement(22251..22787)
                     /locus_tag="KNP54_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBF0891087.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            complement(22789..23856)
                     /locus_tag="KNP54_000151"
     CDS             complement(22789..23856)
                     /locus_tag="KNP54_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBF0891088.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQKAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            complement(23861..24685)
                     /locus_tag="KNP54_000152"
     CDS             complement(23861..24685)
                     /locus_tag="KNP54_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBF0891089.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKNLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIVFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            complement(24693..25385)
                     /locus_tag="KNP54_000153"
     CDS             complement(24693..25385)
                     /locus_tag="KNP54_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBF0891090.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            complement(25409..26284)
                     /locus_tag="KNP54_000154"
     CDS             complement(25409..26284)
                     /locus_tag="KNP54_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBF0891091.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            complement(26302..27423)
                     /locus_tag="KNP54_000155"
     CDS             complement(26302..27423)
                     /locus_tag="KNP54_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891092.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            complement(27836..28660)
                     /gene="spo0A"
                     /locus_tag="KNP54_000156"
     CDS             complement(27836..28660)
                     /gene="spo0A"
                     /locus_tag="KNP54_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBF0891093.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            complement(28802..29860)
                     /locus_tag="KNP54_000157"
     CDS             complement(28802..29860)
                     /locus_tag="KNP54_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBF0891094.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            30021..30461
                     /locus_tag="KNP54_000158"
     CDS             30021..30461
                     /locus_tag="KNP54_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0891095.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            30522..31013
                     /locus_tag="KNP54_000159"
     CDS             30522..31013
                     /locus_tag="KNP54_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0891096.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(31106..31972)
                     /locus_tag="KNP54_000160"
     CDS             complement(31106..31972)
                     /locus_tag="KNP54_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891097.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(32186..33865)
                     /gene="recN"
                     /locus_tag="KNP54_000161"
     CDS             complement(32186..33865)
                     /gene="recN"
                     /locus_tag="KNP54_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBF0891098.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            complement(33885..34697)
                     /locus_tag="KNP54_000162"
     CDS             complement(33885..34697)
                     /locus_tag="KNP54_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBF0891099.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            complement(34830..36695)
                     /locus_tag="KNP54_000163"
     CDS             complement(34830..36695)
                     /locus_tag="KNP54_000163"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBF0891100.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            complement(36729..37166)
                     /locus_tag="KNP54_000164"
     CDS             complement(36729..37166)
                     /locus_tag="KNP54_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBF0891101.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            complement(37196..38083)
                     /locus_tag="KNP54_000165"
     CDS             complement(37196..38083)
                     /locus_tag="KNP54_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBF0891102.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIGKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            complement(38086..38301)
                     /gene="xseB"
                     /locus_tag="KNP54_000166"
     CDS             complement(38086..38301)
                     /gene="xseB"
                     /locus_tag="KNP54_000166"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBF0891103.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            complement(38303..39508)
                     /locus_tag="KNP54_000167"
     CDS             complement(38303..39508)
                     /locus_tag="KNP54_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBF0891104.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            complement(39505..40575)
                     /locus_tag="KNP54_000168"
     CDS             complement(39505..40575)
                     /locus_tag="KNP54_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBF0891105.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            complement(40559..41065)
                     /gene="nusB"
                     /locus_tag="KNP54_000169"
     CDS             complement(40559..41065)
                     /gene="nusB"
                     /locus_tag="KNP54_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBF0891106.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            complement(41150..41512)
                     /locus_tag="KNP54_000170"
     CDS             complement(41150..41512)
                     /locus_tag="KNP54_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBF0891107.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            complement(41622..42311)
                     /locus_tag="KNP54_000171"
     CDS             complement(41622..42311)
                     /locus_tag="KNP54_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBF0891108.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNVDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            complement(42338..42892)
                     /locus_tag="KNP54_000172"
     CDS             complement(42338..42892)
                     /locus_tag="KNP54_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBF0891109.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            complement(42904..43521)
                     /locus_tag="KNP54_000173"
     CDS             complement(42904..43521)
                     /locus_tag="KNP54_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBF0891110.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            complement(43581..44786)
                     /gene="spoIIIAE"
                     /locus_tag="KNP54_000174"
     CDS             complement(43581..44786)
                     /gene="spoIIIAE"
                     /locus_tag="KNP54_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBF0891111.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            complement(44871..45257)
                     /gene="spoIIIAD"
                     /locus_tag="KNP54_000175"
     CDS             complement(44871..45257)
                     /gene="spoIIIAD"
                     /locus_tag="KNP54_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBF0891112.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            complement(45273..45470)
                     /gene="spoIIIAC"
                     /locus_tag="KNP54_000176"
     CDS             complement(45273..45470)
                     /gene="spoIIIAC"
                     /locus_tag="KNP54_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBF0891113.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            complement(45487..46008)
                     /locus_tag="KNP54_000177"
     CDS             complement(45487..46008)
                     /locus_tag="KNP54_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBF0891114.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            complement(45998..46966)
                     /gene="spoIIIAA"
                     /locus_tag="KNP54_000178"
     CDS             complement(45998..46966)
                     /gene="spoIIIAA"
                     /locus_tag="KNP54_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBF0891115.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            complement(47190..49175)
                     /locus_tag="KNP54_000179"
     CDS             complement(47190..49175)
                     /locus_tag="KNP54_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBF0891116.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            complement(49264..49803)
                     /locus_tag="KNP54_000180"
     CDS             complement(49264..49803)
                     /locus_tag="KNP54_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0891117.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            complement(50009..51322)
                     /locus_tag="KNP54_000181"
     CDS             complement(50009..51322)
                     /locus_tag="KNP54_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBF0891118.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKIYGENLKKIV"
     gene            complement(51344..52069)
                     /locus_tag="KNP54_000182"
     CDS             complement(51344..52069)
                     /locus_tag="KNP54_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBF0891119.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            complement(52104..52349)
                     /locus_tag="KNP54_000183"
     CDS             complement(52104..52349)
                     /locus_tag="KNP54_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBF0891120.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            complement(52700..54700)
                     /locus_tag="KNP54_000184"
     CDS             complement(52700..54700)
                     /locus_tag="KNP54_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0891121.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            complement(54731..56449)
                     /locus_tag="KNP54_000185"
     CDS             complement(54731..56449)
                     /locus_tag="KNP54_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0891122.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            complement(56675..57913)
                     /gene="fabF"
                     /locus_tag="KNP54_000186"
     CDS             complement(56675..57913)
                     /gene="fabF"
                     /locus_tag="KNP54_000186"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBF0891123.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADLMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            complement(57942..58166)
                     /gene="acpP"
                     /locus_tag="KNP54_000187"
     CDS             complement(57942..58166)
                     /gene="acpP"
                     /locus_tag="KNP54_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBF0891124.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            complement(58220..58969)
                     /gene="fabG"
                     /locus_tag="KNP54_000188"
     CDS             complement(58220..58969)
                     /gene="fabG"
                     /locus_tag="KNP54_000188"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBF0891125.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            complement(58969..59919)
                     /gene="fabD"
                     /locus_tag="KNP54_000189"
     CDS             complement(58969..59919)
                     /gene="fabD"
                     /locus_tag="KNP54_000189"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBF0891126.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAVLGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            complement(59935..60864)
                     /gene="fabK"
                     /locus_tag="KNP54_000190"
     CDS             complement(59935..60864)
                     /gene="fabK"
                     /locus_tag="KNP54_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBF0891127.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            complement(60973..61959)
                     /locus_tag="KNP54_000191"
     CDS             complement(60973..61959)
                     /locus_tag="KNP54_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBF0891128.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            complement(61985..63007)
                     /gene="plsX"
                     /locus_tag="KNP54_000192"
     CDS             complement(61985..63007)
                     /gene="plsX"
                     /locus_tag="KNP54_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBF0891129.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            complement(63018..63575)
                     /gene="fapR"
                     /locus_tag="KNP54_000193"
     CDS             complement(63018..63575)
                     /gene="fapR"
                     /locus_tag="KNP54_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBF0891130.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            complement(63782..63958)
                     /gene="rpmF"
                     /locus_tag="KNP54_000194"
     CDS             complement(63782..63958)
                     /gene="rpmF"
                     /locus_tag="KNP54_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBF0891131.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            complement(63983..64507)
                     /locus_tag="KNP54_000195"
     CDS             complement(63983..64507)
                     /locus_tag="KNP54_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBF0891132.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            complement(64600..65796)
                     /locus_tag="KNP54_000196"
     CDS             complement(64600..65796)
                     /locus_tag="KNP54_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBF0891133.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            66259..67539
                     /locus_tag="KNP54_000197"
     CDS             66259..67539
                     /locus_tag="KNP54_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBF0891134.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNLAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDV
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(67802..69193)
                     /locus_tag="KNP54_000198"
     CDS             complement(67802..69193)
                     /locus_tag="KNP54_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBF0891135.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(69204..70424)
                     /locus_tag="KNP54_000199"
     CDS             complement(69204..70424)
                     /locus_tag="KNP54_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBF0891136.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(70438..71226)
                     /locus_tag="KNP54_000200"
     CDS             complement(70438..71226)
                     /locus_tag="KNP54_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBF0891137.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(71243..72517)
                     /gene="larA"
                     /locus_tag="KNP54_000201"
     CDS             complement(71243..72517)
                     /gene="larA"
                     /locus_tag="KNP54_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBF0891138.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(72635..73348)
                     /locus_tag="KNP54_000202"
     CDS             complement(72635..73348)
                     /locus_tag="KNP54_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBF0891139.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            73473..74732
                     /locus_tag="KNP54_000203"
     CDS             73473..74732
                     /locus_tag="KNP54_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBF0891140.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            75012..75578
                     /locus_tag="KNP54_000204"
     CDS             75012..75578
                     /locus_tag="KNP54_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0891141.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(75779..76984)
                     /locus_tag="KNP54_000205"
     CDS             complement(75779..76984)
                     /locus_tag="KNP54_000205"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBF0891142.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(77087..77193)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(77285..77653)
                     /locus_tag="KNP54_000206"
     CDS             complement(77285..77653)
                     /locus_tag="KNP54_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBF0891143.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(77705..78982)
                     /gene="obgE"
                     /locus_tag="KNP54_000207"
     CDS             complement(77705..78982)
                     /gene="obgE"
                     /locus_tag="KNP54_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBF0891144.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(79093..79383)
                     /gene="rpmA"
                     /locus_tag="KNP54_000208"
     CDS             complement(79093..79383)
                     /gene="rpmA"
                     /locus_tag="KNP54_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBF0891145.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(79397..79714)
                     /locus_tag="KNP54_000209"
     CDS             complement(79397..79714)
                     /locus_tag="KNP54_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBF0891146.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(79729..80040)
                     /gene="rplU"
                     /locus_tag="KNP54_000210"
     CDS             complement(79729..80040)
                     /gene="rplU"
                     /locus_tag="KNP54_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBF0891147.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(80141..81562)
                     /locus_tag="KNP54_000211"
     CDS             complement(80141..81562)
                     /locus_tag="KNP54_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBF0891148.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(81580..82281)
                     /locus_tag="KNP54_000212"
     CDS             complement(81580..82281)
                     /locus_tag="KNP54_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBF0891149.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGAESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(82283..84127)
                     /locus_tag="KNP54_000213"
     CDS             complement(82283..84127)
                     /locus_tag="KNP54_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBF0891150.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            84446..85639
                     /locus_tag="KNP54_000214"
     CDS             84446..85639
                     /locus_tag="KNP54_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBF0891151.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(85851..86671)
                     /locus_tag="KNP54_000215"
                     /pseudo
     CDS             complement(85851..86671)
                     /locus_tag="KNP54_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428476.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(86801..87592)
                     /locus_tag="KNP54_000216"
     CDS             complement(86801..87592)
                     /locus_tag="KNP54_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891152.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFVFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(87596..87925)
                     /locus_tag="KNP54_000217"
     CDS             complement(87596..87925)
                     /locus_tag="KNP54_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891153.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(88410..88823)
                     /locus_tag="KNP54_000218"
     CDS             complement(88410..88823)
                     /locus_tag="KNP54_000218"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBF0891154.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(88864..89994)
                     /gene="rodA"
                     /locus_tag="KNP54_000219"
     CDS             complement(88864..89994)
                     /gene="rodA"
                     /locus_tag="KNP54_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBF0891155.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(90079..90363)
                     /gene="minE"
                     /locus_tag="KNP54_000220"
     CDS             complement(90079..90363)
                     /gene="minE"
                     /locus_tag="KNP54_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBF0891156.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(90381..91178)
                     /gene="minD"
                     /locus_tag="KNP54_000221"
     CDS             complement(90381..91178)
                     /gene="minD"
                     /locus_tag="KNP54_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBF0891157.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(91202..91885)
                     /locus_tag="KNP54_000222"
     CDS             complement(91202..91885)
                     /locus_tag="KNP54_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBF0891158.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(91983..94961)
                     /locus_tag="KNP54_000223"
     CDS             complement(91983..94961)
                     /locus_tag="KNP54_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBF0891159.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(94973..95461)
                     /gene="mreD"
                     /locus_tag="KNP54_000224"
     CDS             complement(94973..95461)
                     /gene="mreD"
                     /locus_tag="KNP54_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBF0891160.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(95476..96369)
                     /gene="mreC"
                     /locus_tag="KNP54_000225"
     CDS             complement(95476..96369)
                     /gene="mreC"
                     /locus_tag="KNP54_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBF0891161.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(96379..97389)
                     /locus_tag="KNP54_000226"
     CDS             complement(96379..97389)
                     /locus_tag="KNP54_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBF0891162.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(97510..98169)
                     /gene="radC"
                     /locus_tag="KNP54_000227"
     CDS             complement(97510..98169)
                     /gene="radC"
                     /locus_tag="KNP54_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBF0891163.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(98214..98798)
                     /gene="maf"
                     /locus_tag="KNP54_000228"
     CDS             complement(98214..98798)
                     /gene="maf"
                     /locus_tag="KNP54_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBF0891164.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(99018..99989)
                     /locus_tag="KNP54_000229"
     CDS             complement(99018..99989)
                     /locus_tag="KNP54_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBF0891165.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(100005..100580)
                     /gene="rsxA"
                     /locus_tag="KNP54_000230"
     CDS             complement(100005..100580)
                     /gene="rsxA"
                     /locus_tag="KNP54_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBF0891166.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(100595..101188)
                     /locus_tag="KNP54_000231"
     CDS             complement(100595..101188)
                     /locus_tag="KNP54_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBF0891167.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(101201..101770)
                     /locus_tag="KNP54_000232"
     CDS             complement(101201..101770)
                     /locus_tag="KNP54_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBF0891168.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(101770..102747)
                     /locus_tag="KNP54_000233"
     CDS             complement(101770..102747)
                     /locus_tag="KNP54_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBF0891169.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(102770..104107)
                     /gene="rsxC"
                     /locus_tag="KNP54_000234"
     CDS             complement(102770..104107)
                     /gene="rsxC"
                     /locus_tag="KNP54_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBF0891170.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(104323..105267)
                     /locus_tag="KNP54_000235"
     CDS             complement(104323..105267)
                     /locus_tag="KNP54_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891171.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(105378..106652)
                     /locus_tag="KNP54_000236"
     CDS             complement(105378..106652)
                     /locus_tag="KNP54_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBF0891172.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(106784..107155)
                     /locus_tag="KNP54_000237"
     CDS             complement(106784..107155)
                     /locus_tag="KNP54_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBF0891173.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(107383..107982)
                     /locus_tag="KNP54_000238"
     CDS             complement(107383..107982)
                     /locus_tag="KNP54_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891174.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(108183..108395)
                     /locus_tag="KNP54_000239"
     CDS             complement(108183..108395)
                     /locus_tag="KNP54_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBF0891175.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(108468..110183)
                     /locus_tag="KNP54_000240"
     CDS             complement(108468..110183)
                     /locus_tag="KNP54_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0891176.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKVKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(110183..110737)
                     /locus_tag="KNP54_000241"
     CDS             complement(110183..110737)
                     /locus_tag="KNP54_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBF0891177.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(110730..111332)
                     /locus_tag="KNP54_000242"
     CDS             complement(110730..111332)
                     /locus_tag="KNP54_000242"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBF0891178.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(111341..113989)
                     /gene="polA"
                     /locus_tag="KNP54_000243"
     CDS             complement(111341..113989)
                     /gene="polA"
                     /locus_tag="KNP54_000243"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBF0891179.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            114141..114228
                     /locus_tag="KNP54_000244"
     tRNA            114141..114228
                     /locus_tag="KNP54_000244"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:114175..114177,aa:Leu,seq:caa)
     gene            complement(114415..114858)
                     /locus_tag="KNP54_000245"
     CDS             complement(114415..114858)
                     /locus_tag="KNP54_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891180.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(114861..115058)
                     /locus_tag="KNP54_000246"
     CDS             complement(114861..115058)
                     /locus_tag="KNP54_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891181.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(115250..116116)
                     /locus_tag="KNP54_000247"
     CDS             complement(115250..116116)
                     /locus_tag="KNP54_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0891182.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(116342..117211)
                     /locus_tag="KNP54_000248"
     CDS             complement(116342..117211)
                     /locus_tag="KNP54_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0891183.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(117717..117938)
                     /locus_tag="KNP54_000249"
     CDS             complement(117717..117938)
                     /locus_tag="KNP54_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891184.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(118439..119419)
                     /locus_tag="KNP54_000250"
     CDS             complement(118439..119419)
                     /locus_tag="KNP54_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891185.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(119583..120455)
                     /locus_tag="KNP54_000251"
     CDS             complement(119583..120455)
                     /locus_tag="KNP54_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBF0891186.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANSKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(120619..121170)
                     /locus_tag="KNP54_000252"
     CDS             complement(120619..121170)
                     /locus_tag="KNP54_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0891187.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(121190..122092)
                     /locus_tag="KNP54_000253"
     CDS             complement(121190..122092)
                     /locus_tag="KNP54_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBF0891188.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(122107..124479)
                     /locus_tag="KNP54_000254"
     CDS             complement(122107..124479)
                     /locus_tag="KNP54_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBF0891189.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(124700..125389)
                     /locus_tag="KNP54_000255"
     CDS             complement(124700..125389)
                     /locus_tag="KNP54_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBF0891190.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYVK
                     FIYNLFKSLTDTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(125630..127009)
                     /locus_tag="KNP54_000256"
     CDS             complement(125630..127009)
                     /locus_tag="KNP54_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBF0891191.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPYLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(127003..>127679)
                     /gene="rgbR"
                     /locus_tag="KNP54_000257"
     CDS             complement(127003..>127679)
                     /gene="rgbR"
                     /locus_tag="KNP54_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBF0891192.1"
                     /translation="QLLIEDYLENILKDISIEYEIQKYISGEELLESNLKDIDILLLD
                     IKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRYLLKPIELEELKKH
                     VLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIHTINKNFDIKYSLG
                     KIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISRYRYKEVKEKFLKF
                     LGDTIC"
BASE COUNT        40470 a        22996 c        13425 g        50788 t
ORIGIN      
        1 aacgatattg acactacttg aattatatta tagaaaagct gaaataaata aaatagtttg
       61 ggctagaata ggttttaatt tatatctttc taaaggagtt gcattaactt taactgatgc
      121 tggtataggg atttcaggac ttttggctgg tgctattcct ggtataggac agtacttgcc
      181 acttatagtt agattaatta caatgtacct tgagtcaaat ataacatctg gaaaaatctt
      241 taaatttaaa aaatacgtta taataaagga ggtgcttgtg taaccaaata ctacttacaa
      301 tctgtagaaa tcaataggtg ataaaatgat tataaaatat ctactttttg caattgtttc
      361 agcattaatt ttattatttt gtaataaagc attccaacta agtaaattac acaagttcat
      421 tatattgttt gtttcatttt ttatactaac ttttgtagca tcattcatta gtagataaaa
      481 aataagatgg tggggttaac ttaccatctt tttctcattt aatatttgta atattttaga
      541 tactctttat acttgtgtta ctgttatact ttgattagga aaattaatac aacatgagtt
      601 gatgattata ttataaagga ggtatcttct atgaatttta ggaacattta tcttatactt
      661 atgggattgg gaattataat attaactaca ataatatctt taattgaaat taaaattggt
      721 ttttgtaatg aaaaatattt taataaatta gaatcaaaat atggaaatat agatagaaaa
      781 agaactatta aactagaagt actttatcga tatgtaacag gttttgaata tatagcaata
      841 ggattattta caaaaagatt agatattaca ataatagcaa taatattagt agctactata
      901 acagtaatat tatattactt agttagaaag agatatataa ctatataaaa tctaatagaa
      961 ttaatatcaa aagaaggtag caactaatca ccagcaatta aaataatttg tttttcaaag
     1021 ttaataaaag tcttctttat agcaatgatt taaatataat caaatattgt aacggagatt
     1081 tttttatgaa taatttaaga aaacaattaa tcaaagaaat tatataagat ggagaactta
     1141 taaaatctac agatataagt agttttagga gtaaacacag atgacttatt tcaaagagac
     1201 aatagctaca agttatcctc attctgtaat acaaaaatgt ttaatacatt agataagaaa
     1261 tactttaaat atgtttcata caaggactca aaagaattaa taagtaattt taaatctgta
     1321 tataggtcag ttaatgaata agaagcctta tcgactttag ataaaataga ttaaaaataa
     1381 tgtaaacagt atacttcaga aattaaaatt ttgggaaata actggaatgt tgtagcatca
     1441 tcctttagtt ttactaaaat aagtaatatc tataatatat attacaagta taatcgaaag
     1501 atttaataaa tatttcaaaa atgtctcaaa aacaaagtcc agatttacat caaacgcttc
     1561 actcttaaag atattattct tgacaagcga aaatgtgatg aaaaaatgga ctatgaaata
     1621 taaaaattga tataatatat acaatcattt attcatatct tttgatagta gaatataatt
     1681 ttaaaaatta taccctaaaa atttgctata attgttataa tatatataat ttccaaaaat
     1741 atttaaaaac atcccaatat acatttttta taatttatta aaataaaatt catatattaa
     1801 gaaatattaa tagtaaataa gcaattgtta ctataacata ggaattatct ttaaaaacac
     1861 aaattaattt acattctcta attttaaagt atatgtatat ctttgatttt aataaaattc
     1921 acttaaaata ttttaaggtt gaacaatgaa attgaatgcc caagaacttc ctcctcttac
     1981 taatgttgca attaattcaa acccacaatt gtattgaact gaatctctac ctactggttt
     2041 ccaactagaa ggtgcattat atgagaaaga atttgatgtt ggctctttct tttgttgctg
     2101 cttaattcct agctcattag aaataaatcc agtttgattt atatgcaccc ttctatttgt
     2161 tacacgaatc tggccgtctg caatagacca gtttccagaa actttactaa cggaaatata
     2221 ttgaaatgct ccatctcctt ttgatattgt atatgtaact gtaccagatg cttttacacc
     2281 accagtttta tcccatccat cttctgatat acttgctttt ctaagaggct ttattgtatt
     2341 agtatcaaaa aaactgtctt agaatatatc tttgatgtta aatttttaga ttgtttaact
     2401 tctaataatt gagttgttga tatagaatca acgtatatgg actctcctgt tcttgcattt
     2461 ttgattatac ctttttcatt ggaactttta acatcagtaa ttccattttt agccatatcg
     2521 tataatttgt ccatgtctgt tacttgtttc tctgaataca ttactttcat agatgaatct
     2581 tctaccttac tagcacttgc atttgttggt aatagtattg tcattatgag taaagataaa
     2641 atagttgtta cagatttttt taacctataa ttcatattaa tccttacttt ttatttgtta
     2701 taacagacat tctattgtaa tagaatataa atccacaata tttttaaaat tagtattgaa
     2761 taactattct catgttataa ttattcaaag gagggattga tatgaggaaa aaatttttta
     2821 taggtattct tatagtttta ataatctctg tgatagctat acttaatata aaaaatgata
     2881 aaaatgtctt tattggagaa tcagaaaatt ggaaagctaa atttgtaact actgaaggac
     2941 actcaaaatt agaaataaaa tataaaaata gtaaagatgt agttgaacaa aaatttaatt
     3001 attcctatca atttatagat ggtgaagatg cagttgtagt tgtaaaaaat gaaattttag
     3061 aagcaggtca agaaaaagca ataaaaatac aaagaccagg tctttattca aatagagaat
     3121 ctagttacaa gctaattata tcttggaatg gaaatgagga aactataaac ttgaaaaaga
     3181 aataaccata ttatcaattt ttaaaaaatt attattcaaa ttcttataaa aagagtgttt
     3241 agaaagatga aacactcttt tttgtataag tttttgaaaa ctataaatga aatatatcaa
     3301 aatcgttcga aaaattactg aaataaactc ttaaatatat tataaattaa ggtatattat
     3361 acatgaattt attgggagtt tatgagtttt aaaattggaa accaaacaat aagggcgaaa
     3421 aatacttcaa ggaaaatata taaagttcta taaattatca aaaatatttc gcaaaaattg
     3481 ataattatta caaataaatt gataatatta gaaatatcga aattgaacaa actaggatta
     3541 aagctcaatt agaaaaatcc actaatcctg aaaatacttt gttattctca tttattactg
     3601 ttgttttttc attatttgct aatttatttt tcagttcatt aaatgttaaa tataactcta
     3661 taaacttaat tttacagtta atatgtatta tagttcttat atttatatat attaatacat
     3721 ttttatatcg cctcttcaat ttgagcccca tcattatata aaattaacct acttgatatc
     3781 ttaatttaat atatgtacac tattcatatc ttaatagtca atattattca tttttaatag
     3841 ctctttttag atgtcagaat tattatattt tgaaatttat taaatttttg cattaaaaaa
     3901 actagaaatt aatttaagtc ttgaattact tataactttc tacgtatcta cctttatatt
     3961 cttactctga ttttatatct aatattaatt cttcatcaaa gctattaaat atacctctaa
     4021 ttgagttaat tatttcactt acttcacctt taatttttat attaacttcg accatttcaa
     4081 atctcatctt tttatcttat aatttctata agttttttta tttattgtgt tgctactttg
     4141 accagcactt ttttatttaa tagtctaaat gatatttttt accagtttta atatccttaa
     4201 atactatatt tactaaaaac ttataatttc ttttaataca tagttaatat attcttatta
     4261 ctaataacaa tactcaacaa ttttatcgcc ttttttcaaa tatgatttaa cttttttatt
     4321 cctaattatt taaaaatagt tgtccaattt tcttctatga gaaagtgcta agtattagca
     4381 acttctctat tctcttaact ttctactgtc tcaactttct tcatagctat attaatagct
     4441 acttctttag ctacttcatt gaactcttcc catcttctcc tattttcttc atcagatata
     4501 cgtggatata ctatataaac ttctgtgttt tgattagcta taattttttc atcatattct
     4561 atattttttt ctttatcata tttgtatggt ttaaattgtt gtagtatttt cataacatca
     4621 ccccttgtta taaaatatga actcataaac ttgtcttata cttatttaat tgttacaatt
     4681 tttacttaaa atcactttat attctatatt ttaaagctaa atcctttaca aaagtaacat
     4741 attcttctat aagtttctta tcctcttaca tagtatctag tttgtttaac ttatctcttt
     4801 taaacttaca tacgccttct tctgccattc gtcttttatt aattgttaac cttgtttcaa
     4861 gagacacacc aaaactcttg ttaagaagct cttagctctc attagcaaaa tattttacat
     4921 aacttaaatc accttgactt ctagctattt taactgttaa tagacttgtt tcttttttcc
     4981 aatgtgttat atttaatata acaacatctt ttattatttt aacttctatt tttacatcta
     5041 atgccatatt attgctttat taatttgtat ccttaaatct taaattttct attaatacat
     5101 cttctataca gcttagtttc tctcgcttaa tcttgaaata tattttctct aaattgtcaa
     5161 attgttccca agttttatca atatctaata ttttgcagtg tctatttgca catctttcga
     5221 tccaaaggta taattgacta gaatgttttg aaatcaactg actattaata gattagttct
     5281 taaattcttt caaatactcg aattgtaata aaacataatt tacattctct ttatttctat
     5341 tgaagttagt ttatatattg tttacatcat tttcatatat atctgctagt tgctatgcat
     5401 ttaaaattct cttattattt ctttatatta cttgtaaatt attcatcctc atcatcctct
     5461 taattaaatt tctatcttag aaatttaatt tgtaaaaaaa ttttctatat cataatcaag
     5521 tatcttagat agtttatagg taacatatca actctaattg aatattcccc tttcctgtac
     5581 ttaaaataaa ttgatgcatt tttaaaacct aactcatttg caacactttg taagtataaa
     5641 ttttatgtat gtcttctttt ttataaaatc atagtgtatc tttttcatat attcacatta
     5701 attgctatat ttcaataaca atatttccaa aacagaaact tttcgagata attatgtatg
     5761 gatgtaaatc aaaggattaa atatattagg gaaaatatga atagttctca aaaagaattg
     5821 cttgaaaaaa caaatataaa tacaagtgtt atgaatagaa tagagtctgg tgaaagacca
     5881 acaagagacg atgggttaat aatatttgct aaaatttttg gtttatatac tgattatatt
     5941 cttggtttat cagatacaga aaaactaaat attggcaatt aaagctgaat taattgtatt
     6001 atatgtgtga tgaatataaa tagagaattt tttgaaaagc ttgaaataac ttagaaaaaa
     6061 taagaggttc actcaagaac aagttgctaa agattaaaaa acaacaaagg tatctactaa
     6121 aagatatgaa aatagtttaa gagagttgag tctggaaata tttatgtgta ttctttaaat
     6181 aaaaatttat tttttaaatg ataattaaat ttttactgat atggctatgc ttttaaaagt
     6241 cctaacctta ttttgatatt atatctgtct ttacatacca cttaattaat ataaaacagt
     6301 ataaaaatta gttacagatg tatctttttt gttctttaca taccacttag ttaatataaa
     6361 actattaatt ttcctatgct tgtactcata ctcaaaaagc tttacatacc acttagttaa
     6421 tataaaacga ttgttatttt acgaaaggta cggtcgtaat ttacgacttt acataccact
     6481 tagttaatat aaaaccccaa aataaattga gcatttccaa gacttacatc tatacaattc
     6541 tctcaaattt gcagtgaacc acgagtagtg caaatgataa tatttatcat ataccctcaa
     6601 tgccttatgt ttcaactgtt aagccctatt ttatcaaaaa tatcgctcac tgcaaaacta
     6661 tttataatat tatgaatata ttatttttaa atatctgtac caatttgtag tataataaaa
     6721 tcaagaaaat aatttactcc tataaagagt gattattttt aagtgaaaat attatttttt
     6781 taaatcattc ttattggcgt ttgggagatt tttattttat cataaatata aactgatata
     6841 acaccagctg acatgcttgc cactttagat tattattctt gctacaacta ttataacata
     6901 taaaacttac ttatttttac caaatatttt atgtaaacaa taaatattaa cttatgaaat
     6961 atctgctcat ttacagatat ttaataagtt aatagctcta taataaaatt tttatcattg
     7021 tttataaaaa attttacttt gcattttttt ataaacaaca gttttattta taatgttttg
     7081 tggtataata aaagcaagaa gaactacaat ctattttgcg ttagagtgga gttcatcata
     7141 aacagagttt attttttgga tttaaatata aatttaaatt caactcgtaa gtcactcttt
     7201 gtgcgagagt ggctttttgc ttttttgaat agtttactaa ttaagtaaac taccacacta
     7261 gctgttaaac tagctaaaac attaaacaaa aagttatcca tgaactcacc tcccttcgaa
     7321 tcgttgggag gataatcttt tgtacatgaa ctccactcta tagattgtaa gttaaatctt
     7381 cttgctaaaa atattataac atattatggt aaattatata attaaaaaca cttgtttaaa
     7441 agttctaatt ttaattataa actttcccag tttctatatc tataaaaaac caaccaaaag
     7501 taccattact attttttgaa ttgattttaa cagcatagac attaccacta tatatatcat
     7561 ctctaaaatc tatcatatca actactaagt tattgatact gactttatgt ctcttagcac
     7621 attcttttaa tgctatctgt tttgcttgtt cctctgttat acttccttta tttttataat
     7681 catctggatt acatactttc atattaccat taacatcata tgtataaact ttgctcatat
     7741 catttttagc tacacagtat ctaacatcac cctctgcacc ctgtttaatg taagcaaata
     7801 catagtactc ttttcctgaa aaatcaaaat ttttatctag tagaaatatt aaatcttcat
     7861 cttctgaata attaggttcg taataaaatt tcttcacacc taatagtttt ttcactgcat
     7921 tagcagcatc ttctactgta tattctcttc cagtattaga atcgcctata ttttttgtta
     7981 catttaaaca ctgctgtaat atactatcac tcaaatttcc tatagcagtt aatttagttg
     8041 tacttttcaa tacactttta ttactatcat tatcaactaa cacaatagca ttatttttag
     8101 caacagtaga accaacaaga gcatacacta aatcagtacc acttgctata taaaattctt
     8161 ttactccact ataaaattta tttattatct ttttgttagt atcatatcta tctgtcccac
     8221 ctaatctagt tgaattagta tccttaacta ttttgtcatt cattgatgaa gtaccaccta
     8281 ttacataact ttctacacca gttgtattaa atggaacact ttttccatca gttaatacta
     8341 tagctgcttt atctctaact gctacaggtg cagcactcat tgcatcaggc tctcctttaa
     8401 atgcattagt caatatgact ttatttactt tgttaattga gtttatttct tttgcgacat
     8461 tatagcttgt cttaattcta tcactacctt gaagtctttt aatctctatt cctttgcctt
     8521 ttagaacagt ttcagtatat ttatcaatag agttttctcc tccaattata tatacttttt
     8581 ttgccttttc taatctttta agtgtagcat ttggtatgtt atttttctta gtcaaaagaa
     8641 ttggagcgtt tatagctcct gcaagtccac ttgcacttaa tccatcagcc attgtactgt
     8701 ctgcattaat taatatagct gtagtatagt tttgtttgtc tgcaattata ccagcagttt
     8761 cgtatttatc tgcaccttta attgattcaa ttttatcaag agcatttaca gatatagggc
     8821 aactagcaat aaatatagat aaagataacc ctattgttaa taatttttta attttcataa
     8881 tatctccttc tcttaaatat tttcacctaa attatataat acttttcagg aaaattttac
     8941 cataaattta aaaggttatt attacttaat ataatattaa tgaaaaatat cactcttaaa
     9001 ttaatgactt tggtagaata tggtgataaa ataaaattaa tgagagacaa tataaggggg
     9061 attatattat gataatcagt aaaaaaataa cagcaatatt agtatcattt ttaattatga
     9121 tatcaatggt tggatgtgct ccaaaagaaa gtgctacaga agtagctaaa aagtaccttg
     9181 atagtataga aatcaaagac tacgaagtag catataattt attaagtaaa gacagtaagg
     9241 aaagtgtcag tctagaaaaa tttgaagaat atcaagatac tttatttaaa cttcaaaccc
     9301 taaaagatta taaacttggt gaagaaaata aagtagagaa atacaaatat tctaataaag
     9361 agtacacaaa tcttgttaaa ataaaagaaa ctgatactat aaagtatatc actgaaaata
     9421 aagaagatac tgcaaatttt gatagatatt ttataatcga agataatgaa tataaattat
     9481 tatggcataa agactttaaa agagctctta gctctaatta tgtcaaaatc gctaggtcag
     9541 aaacagaaaa agatgaagat aaggattata ataaagctgc tattgatatc aaaaaagcta
     9601 tagaaattga tgataaaaat ccacttgcat attatacaca atcatatatt tatatagagt
     9661 tacaacgata tgatgaggct ttaaagtcaa ttgataaata cttagaatat ctagataaaa
     9721 ataatgaagc ttataaaata gacgctagtg atgcttacaa tttaagaggt gttattttta
     9781 tgagtaaatc agaatttaat aaagctagag aatcttacaa taaggcgctt gaacttaacc
     9841 cggataatga atatgcaaaa actaatctaa atgatattaa aggattataa ggcattaata
     9901 ttatagaaaa taagtatgtc aaaagttaaa ttaacttttg acatgcttat tttctatatt
     9961 ttaaactcta ttgatttact atataatagt gcataaggag tgtgattact tattatgagt
    10021 gttgccatat acttaagaaa atcccgtgct gatgaagagg cagaaaaaca aggcgaattt
    10081 gaaactttaa gtagacataa atcaacccta ctaaaactag caaaagaaca aaacttagat
    10141 gtaattgaga taaaagaaga attagtttct ggtgaaagta taatacatag acccaaaatg
    10201 cttgaacttc taaaagaagt tgaagaaaat aaatatgatg cagtcttagt aatggactta
    10261 gacagacttg gtcgtggaga catgaaagac caaggtatca tattagaaac attcaaagaa
    10321 agtaagacca aaatcatcac acctagaaaa acatacgacc taacagatga atttgatgag
    10381 gagtattcag aatttgaagc atttatggca agaaaagaat taaaacttat atcaagaagg
    10441 atgcaaagag gtagaataaa atcagttgaa gaagggaatt tcataggaac ctctgctcca
    10501 tttggatatg atgctgtaac aactggtaga aaagaaagaa tacttgtacc aaataaagat
    10561 gctgatgtag ttaggactat ctttgactta tatattaatg aagatatggg ttgtagtaaa
    10621 atatcaaaat acctaaataa cttaggcatt aaaactgcta caggtgctaa ttggtacaat
    10681 tctgcaatta caaatataat aaaaaataag gcatattgtg gctacattca gtggcaaaaa
    10741 aaggactaca aaaaatctaa aaatccaaat aaaataaaaa cagttaaact aagacctaaa
    10801 gatgaatgga ttgaggcaaa aggaaagcat gaacctttaa taagtgaaat aacatggaaa
    10861 aaagctcaaa atatactcaa aaaaaatggt catgtcagct atggtaatca aataaaaaat
    10921 ccacttgcag gaatagtgat ttgcaaaaat tgtggtagac cattagtata tagaccatat
    10981 gcagaccacg actatataat ttgttatcat cctggttgca ataaaagttc tcgatttgaa
    11041 tttattgaag ctgccatttt aaaatctttg gaagacactg taaaaaaata tcaattaaaa
    11101 gcatctgata tagacttaga taaaaataat aaagatagta atatagaatt tcaaaaacga
    11161 gtcttaaagg gcttagaaac tgaattaaaa gaattaggca agcaaaaaaa taagttatat
    11221 gatttactag aacgaggaat atatgatgaa gatacattta ttgaaaggtc caacaatata
    11281 agttcaagaa ctgaagaaat taaagattca attaagacag taaaaaatag attgagtact
    11341 gttaaaaaag acaattctaa aataatagaa gatattaaaa ctgtgttatc actttaccat
    11401 gattcagatt cccttggaaa aaataaactc ctaaaatctg taattgataa agcagtttat
    11461 tataagtcta aagaacaaaa actagattct tttgaattaa tggtccattt gaaattacat
    11521 gaagaccagt aataccaata acatataaag agtagtgtgt aatgaaataa gtcttttaga
    11581 tatacttggt acagaggcta actatgttct tgatgaagtt gaactaaaag ttcaagttgg
    11641 aaaactttac gaacaactaa acaaaattct tactcctaga gaaagagaaa ttgtccagtt
    11701 aagatatggg ttaactcctt atggctataa gacacaaaga gaaattgcac aaaaactcga
    11761 tatatcaagg tcatatgtat ctagaatcga aaaaaaagct cttaaaaaac tagaaaaaga
    11821 gcttgttcaa gaaagttaat actatatttt aaaaggatat atcgtacatc attagacaaa
    11881 attttctatc taaaatcaaa gttacgatat atccttaaat tttatagtac ataatttatt
    11941 ttatactttc acatatttcc ttaaatatag gtgttgcaga tttatttcct ttttgagttc
    12001 cttctactaa cacagttatt acatacttag gtctttcttc aggataaaat cctgttatcc
    12061 atccgtggtc tatagctttt ttatttaaac tactttgagc tgtaccagtt ttaactccac
    12121 aaccaccttc aatatctttt aggtctttag ctgtaccagt cctagataca gacttcatat
    12181 attctttaac ttgtgtacac acataaggag aaataagttc ttcttttttt gaagacttat
    12241 aagtttttat tgtattcata ttattgtcca caagactttt atataagtat agtggtttga
    12301 atgttccatt attagctatt atttgagtca tttgatttat ttgaagtggt gtaaattcta
    12361 tattttcttg acctatagct aaatttctta ttgatatgtt ttttggagct tctctaattt
    12421 tttcttcatc aagaccaata tcaacctttt caaataaatg taatttttca gcagatttga
    12481 gtatcttttc ttttccaagt ttcatagcta tatctaaaaa tgcaggattg catgaattag
    12541 aaaaagcttg tcttaagttt tggaaaccat gaccatctct tttattacat cgcagtattt
    12601 cattagtatt cccaacttta gtcttacctg tacagttgta agtatagttc tcatctataa
    12661 caccattttc aagtgcagaa aataaaacta ccatcttaaa tacagaccct ggtggatatg
    12721 tcgcttttat aactctattt tcaaattctc cattttttcc ttttaaactt tttgatatgt
    12781 cattttggtc aaaattaggt ctagagcaca ttgcaagaat ttcacctgta gatgcttccg
    12841 agattattgc tgctgtagga ttttcttctt tatttagtat ttgttctaat tttttttgaa
    12901 tgttataatc aatagtagtt tttagatgtc tatctttatc cttattatca acagttttta
    12961 cacttccctt tagtatgttt agagattttt catttcctgc atctccagct ttaaaagcac
    13021 ttatatactt ttcatttgaa tttctaagta cactatccat actcttttca attcctgatt
    13081 gacctgattt atcatcttct tttatatatc ctattgtatg tgataataaa ccatcttttg
    13141 cgtacctcat agttttttct tctaccatta ttccattttt ctcaagttct tttttcatac
    13201 tcttatcgat atcgatattt ttagtctgaa tctgtattat agggcgtgtc aattgctctt
    13261 gtacagcttt atatatatct aaatcattca tcttagtagc tttcttaata agctccaaaa
    13321 ttttatagtt attatttaat ttttcttttt caacaattaa tacctgagat ttacttgtat
    13381 ctgtaagctt cttgttgttt ctatcataga ttattcctct tccactattt aactcgactt
    13441 tctcaacgct ttgtgattca acactttgtt tgtatttatc accttttaat acttgtatat
    13501 caactagcct ataaattaaa acactataaa ttattaaaat tatagtaaat atacaccagc
    13561 ttctctttcc cacttttttc aaaaatggag tcttcttttt tgacatgaaa tcacccctta
    13621 gataatttca ttattgacaa tttctaaggg gctaatacta tttttatcaa ttttttatta
    13681 ttcttcaacc ttttcttcta taacttttct aagcatataa tctttaccaa cttttactga
    13741 tagctttaac ttcactattt gtctaggatg aggagctgat tctatagctt ctccttcttc
    13801 attatacatt tcttcaattt tagtaaacat agtttcttta tatggtccca taacttctat
    13861 ttcatcacca acacacattt tatttctttg ctcaacaaca ataagaccat cttcatcttc
    13921 tgtttctcta actataccta taaaatcata gtttctaaca tatgatgctg attgataatt
    13981 ttggtcttct gttgttggtt tattcaagta aaaacctgat gtaaaatgtc tatgactacc
    14041 tttttttagt tcttccatcc acattggatt aaacttccag ttttctgggt ctctgtaaaa
    14101 ttcatctatt gccattctgt atgctcttac aacagtagct acatagtatg cagtcttcat
    14161 tctaccttct atttttaaac ttgttatacc agatttgatt aactctggta tatactctat
    14221 catacataaa tcttttgagt taaagaagaa tgtacccctt tcatcttcgt atattggaaa
    14281 atactcacca ggtctttttt cttccaccaa atgatattgc catctacaag attgagcaca
    14341 agaacctttg tttgcatctc ttccagtcat atagttgctt attaaacatc tgccagaata
    14401 agaaatacac atagcaccat gcataaacgc ttctatatcc atatctaaag gtgtttttgc
    14461 tcttatctca tatatttcat caaaagataa ttctcttgcc actacaactc tttttattcc
    14521 atgctcgtac cagaagtttg cacttagata attggttgta tttgcttgtg tacttaaatg
    14581 tatttccata ttcggaatta cttttttaat gacactaagc actcctgggt cagctattat
    14641 aactgcatct attcctatct cttctagttc caacaaatag tcttctaatt gtagaaaatc
    14701 ttcattatga ggtattatat ttactgttac gaatactttc ttgcctcttt catgtgcaaa
    14761 agctactccc tctgccatat cttccttact aaaattcttc gctgcagacc tcattccaaa
    14821 aatttctcca cctatataaa cggcatctgc tccatatgtt atagctattt tcaatctctc
    14881 caaatcacct gctggagcta aaagttctac tttatttaat tccatctaca tcacctcttt
    14941 tactttcttt ataacttagt gctacaccat cacctattgg taccaatgat gtgcttaaat
    15001 agtcacaatt acatatataa tctaaatact ttctcattct tttaactata gtcttttttc
    15061 ttcttacaac aaaatcatca tgagcaacca tacctttata caaaatattg tcagatacta
    15121 aaagtccccc atcttttaat ttatctataa ctaaatcaaa aaatagctta tattgacctt
    15181 tggctgcatc tataaatata aggtcaaatt caccttggac ttgactaagt ttttcttctg
    15241 catctccttc tagtatagtt atgttattgt caaatccagc taattttatg ttttcttttg
    15301 ctttttctat cattttttca tttctctcaa cagttattat atctgcatct tttcctataa
    15361 tagttgcaaa aaaaatagaa gaataaccaa ttgcacatcc tacttctaaa attctctttg
    15421 gtttttgaac ctttaacaag acttttaata aatctgaaac ttctttatgt attataggaa
    15481 cactattttc ctctgcataa atttctaaat cttttaaaaa tccttctttt tcttttaatg
    15541 tcactcttat ataatcttca accaaatcat taactatatt actcataaaa acactcccta
    15601 aaataataaa tatccaagtt ttatattaat ttattatttt ttaaattcat attgttatat
    15661 atatttacac tttctttatt ataaatctaa gaataacaat tttcaataaa aaagcccaac
    15721 attattctta ccctgttaga ctttttataa tcatggttta tttttttgta ttttctttat
    15781 ttgttgcttt tgtatctttt gattgtttat cccttgcttc tttatattct ttaacgtatt
    15841 ttaaatggtc ttgatagttt gtactataat tatttccacc atcaatctta gctacaaaat
    15901 ataaatagtc tgttttctct ggatataatg ctgcttcaat agattttata ccaggatttg
    15961 atattggtgt aggaggtaat cccttatttt tataactatt atatggtgaa tcaattttta
    16021 aatcatcata tgttacaatt ttctttctct cttcaaatat atattgtatt gtagcatctg
    16081 attgaagagg catacctacc ttaagtctat tataaaacac acttgctatt ataggtctgt
    16141 ctttgtcaag aacagcttct ttctcaatta ttgatgccat ttccattact tcttgaagag
    16201 tcatatttaa ttctttttgt ttctttttaa acttgtccgt gtatttactg tcaaatactt
    16261 ttaacatttc gcttaaaata tcttcttctg attgtttctt tgaattaaaa taataagttt
    16321 ctggatacaa gaacccttct aaagaggtta ttccatcttc cttcaaatat gaaaatttat
    16381 cataaaattc ttgaggtttt tttattaaat tttcaaaagt agctttatct cctaaatttt
    16441 tacttactaa cattgctata atttctttag atgtagctcc ctctggaata gtcactttta
    16501 taccatcctg atatatttta cctgaaacta aaagacttat tatatcattg tttgaatacg
    16561 attgattaag taagtatgtt cctgatttta tagacggagc tttattgcta acctttacca
    16621 aaagtttaaa taatagttca ttctttatta atttattttc atataatatg tcagatattt
    16681 ttccaacaga tgctccactt ggaacgtcga taattacatc ttttttgtta tttttatcat
    16741 aaggacctat ttgtataaac acaaatatac ctgctaagat aatcaaaata acaattatta
    16801 atactgctat tttcaatcta ttttctttaa agttcataat ataatctact ccttatgtat
    16861 atttatccat tttctattat aaaactagat actttaattt tcaatcatct tgtagaataa
    16921 acttatttat attgtaaaaa atgttttaaa atatatattt ttggtataat ttatagttta
    16981 tcaaaaaata aaaaacctaa cattattttt gacatgttag gccttttata atcacttttc
    17041 taaaattttc taaaactttt taatctcttc tttagttaca ataccatata ttaatttatt
    17101 tttttctatt tttgaatcta caatagagta ggaatcaata aatcttccct ttgccaatga
    17161 aagcttttgt tcatcattat aatacatgta agctaaaact tcaccttcat ttacataatc
    17221 tcctactttc ttttctaaaa ttatccctgc tgataaatct aaaatatcat ctttagtttc
    17281 tctacctgct ccaagaatca tagccgatac accaacatct tcagctttaa ttttgcttat
    17341 ataacctgat ttagttgatt taactggata tttatacttt gattttttga ataaagaata
    17401 atcatctact acatctttat taccaccttg attctctata aactctttga gtttttgtat
    17461 agcagtacca gattttattg attctcttat tttttcaaca ccatcttcaa aatcatgtgc
    17521 tacctttgat aaaaccaaca tatatgctcc taatacttcg catagctcaa caaggtcttt
    17581 aggtccattt ccttttaatg tctcaattgc ctctataact tctaaagagt ttcccactgc
    17641 aaaacctaaa ggttcatcca tatctgttac aatccctatt gtatctctat tcataccagt
    17701 acctatatca accatagatt tagctaactc aaaagactct tctaatgtct tcataaatgc
    17761 tccatcacca gtttttacat ctagcacaat tgcatcagct cctgaagcta actttttaga
    17821 cattacactt gatgatatca atgatatatt atcaacagtt gctgtaacat ctctaagagc
    17881 atatattttc ttatctgcaa ttgctacctt tgcactttga ccacaaactg ctattttaga
    17941 cttatttaca gaatcaataa atttacttat ctccatttct gtcgaaaaac ctggtataga
    18001 ctccaattta tcaatagtac caccagtatg accaagacct ctacctgaca tctttgcaac
    18061 tggtgctcca catgaagcaa ccaaaggtat aagagctatg gtagtcttat ctccaacacc
    18121 accagtacta tgcttatcta cctttattcc atctatctca gataggttta tcatgtctcc
    18181 agagttcatc attgcttctg taagatgtac agtttcctgt ttattcatct tatttaaata
    18241 aatcgacatt aatagtgcag aagcttgata gtcaggtata tctccctttg aatagttttc
    18301 tataaagtag tttatctctt ttttactaag ctctaggtta tctctctttt tttttataat
    18361 atcatacatt ctcataattg aaatctccat tctaacctat aataatttaa ataaatatta
    18421 aactttaaaa cactttcaaa tgttgtagta ttataaaaaa actgtccttt attagaaata
    18481 actttctata tcaagacagc tttttattaa ttcttttcaa attaaacatt aactatttta
    18541 ttataaactt cctcaaaaaa tctataataa gctttaactt ataaattttt aaccgttgtt
    18601 ttaactaaat tcataaattc tgatttaact ttttgagtag tttctattac ttcctcatga
    18661 cttagtggtt gatttaagat gccagcagcc atatttgtta tacaagatat accaataact
    18721 cctatattag agtgagaagc tactatgact tctggaacag tagacatacc tacagcatca
    18781 gctcccaaaa tttgtgccat tctcacttct gctggtgttt catagtttgg accactaaaa
    18841 aacatataaa cgccttcttt gacatctata ttgcattctt tagcgcagtt tttaactaca
    18901 tctacatatt tagaagaata tgcatctgac atatctggaa atctagcacc aaatctgtca
    18961 tcattttttc ctactaatgg attacttcca ctaaagttta tatggtctct tataagcatc
    19021 aaatctcctg ctttaaattc tttatttacg cctccagcag cgttagttac tataagaatc
    19081 tcgactccta attctttcat aacccttact ggaaaagtag cttctttctg agaatatcct
    19141 tcatagtaat gaaatctacc ttgcatagca ataacttctt ttccttcaag ttttccaatt
    19201 acaagttgtc cagcatgtcc tgctactgtt gatacaggga agtttggaat ttcactatat
    19261 ttaattgtga cagggtcttc tatatcattt gctaaatcac ctagtccaga acctaatatc
    19321 aaaccaatct taggttttat attactttta gaatttataa atttactact ttgtgctatc
    19381 ttttcaaaca ttccaatctc tccatcctat taagctaagt ttttatcatt ttatagttta
    19441 aaataaatct tctttaaagc ttgacccatg tttaggcaac tttacattta gtatatctgc
    19501 aacagttgct ccaatatcag caaaagtatc ttttactcct aaattaaaac cttttttaat
    19561 cttattgcca taaatcataa caggtatata ttctcttgta tggtctgtac ctttatatgt
    19621 tgggtcattt ccatggtctg cattgattat taaaatatca tcttctctca tattagccat
    19681 tatttcagga agtctactat caaactcttc aagagctttc ttatatcctt ctgggtctct
    19741 cctatgacca tatttagaat caaaatcaac gagatttgaa tatattagac ctttattatc
    19801 ttgtttcata taatttaaag tttcatccac tccatccata ttgcttttag tgtggatagc
    19861 atctgtaatt ccttttccat taaaaatatc ttctattttt ccaactgcta aaacatcaag
    19921 tcctgattct tttatattat caagaactgt tggttcaaat gggtctagtg aataatctct
    19981 tctatttgaa gtcctcacaa actcaccttt tttcttacct atgaatggtc tagcaattac
    20041 tctagctact gcattatccc ccatcattat ttccctagcg attttgcaca tattatagag
    20101 ttcttctagg ggaattactt cttcattagc agcaatctga aatacactat cagctgatgt
    20161 atacactatt acatctccag tttttatttg atgctctcca tactcatcta ttattacagt
    20221 tcctgaagct ggtttatttc ctactacttt tcttccagtt tttttctcaa actcttctat
    20281 tatctcctta gagaatccat gttcaaatgt cttaaatggt ttgtcaacta ttataccagt
    20341 catttcccaa tgacctgtag tagtatcttt tccctgagac atttccttac actttccaaa
    20401 acaacctatt ggttctttta tactttcaaa aaaatctata ccttctatgt ttcctatacc
    20461 taaatttctc atattaggaa tctgaatatc tggatattcc ttaaatatat ttccaagggt
    20521 acttacatcc ttactatcac caaatttttc agcatcaggt aatgctccta tcccaacact
    20581 atcaattaca atccaaatta ctctgctcat ataaatatgc tccttctaaa ttataaaatt
    20641 tgctatatag tctatttagc ttctgctttt tgtaattcta catcaacatc atttctagga
    20701 tgtttctcct ttatttctct tctcacgttt ttatctatat gatttaaata tacttgcaaa
    20761 ctagataaat taacatttcc taaaatttta cttacaacag caatgttagc accttcattt
    20821 aacaaatgaa tagcaaatga atgtctaagc attgtaggat ttatattttt atctatattg
    20881 gctagattag aatatttttt tatgactttc caaagacctt gtcgtgtaaa cctttgacct
    20941 aatgaactta cgaataatga tttttcacct tctgcagcca ttttaggtct tgcttctttt
    21001 agatactttt ctaagtaaag ttttgtaata tcacaaagtg gtatcactct ttgattttta
    21061 caacatgaat tacaatatat ataatcaata tctaggtcaa tatcctctat attcatctct
    21121 actaattcag atacttttat accagtacca tataatactt caaaaatagc cttgtcccta
    21181 atcaacttag gtgttgttaa ctttggaaaa tttaatagtc tttcaatttc ttcttctgta
    21241 agtatattta tattttcttt ttttatttta ggttttttta tatcctttgc aggattattt
    21301 gtacatatat gatttaaaaa taaataatca tgaaaagatt ttatagagga tatcatcctc
    21361 gctattgtag ctattgatac attatctttt tccaacttta ttaagtaact tataatatca
    21421 ttttctacta tatctactag tttaatgctt ttttgattta tatattccat atattttttt
    21481 atatccataa agtatgatgc cactgtattc tctgataatt tttttttatc ttttatgtaa
    21541 tctatatatc cctctataat atccattata aactccttta tttagctagg aacttaataa
    21601 taccaatact tgcagtattt aatattaatt gcaaccccaa tgatagtgct attataatta
    21661 taatatttag tatatacctc ttaattaaaa attgcatatt ttttctactt ttctttttaa
    21721 attcataaac catttcttta aaataactta aactaattaa tgctaatatg attgcacatg
    21781 gaataataat caaattttta aataatatta ttaaaatcat ttttatactt ttaaatttta
    21841 atgccaatat acaactattt attgtataac caattgacat cccttttaat acaaaagcta
    21901 ccaacactgc tggaattgtt actacaaata gacttaatag agctattgag cccataaaga
    21961 ttgcatctga ttttaaattt tgtatcactg tatcttttat gcttatattt agattataat
    22021 actctacagc aggatttata ttgtttaata tattgttact agaacctggc aatattttat
    22081 ttatgtaaga cccaacaaca atagacatca taaacaacaa tcctataata attatttgtc
    22141 tatttaattc tctaaaatca ttttttctat atgttcttct caatttaatt cccccttgtc
    22201 ctttataaaa taatatgctt taggacaaag ggttattcat tttataaata ttaattttta
    22261 aacatatctt ttactaataa taatccaata gatgtttttg catcttcaac gtcatttttt
    22321 aataccatgt tatatgcttc ttcaagctca atttcataaa catctaaaaa ctcatctgca
    22381 tctaaattat tctctcctgg agtaagacct gttgctaaat atacaaacat tatctcatta
    22441 gaaaaacctg ctgaagtgaa aaatttatgt attagcttaa tattttttgc actataccca
    22501 gtttcttctt ttaattctct ttcagcacat tcttttggac tttcattttt ttctagttta
    22561 ccagctggaa tttcaaagat tggcttttct ataggttttc taaattgctt aactaacaca
    22621 actttattat catctgtgat tgcaactatt cctactgctc caccaacttc tactaactcc
    22681 cttttttgat atccttgccc tggaatttca acagtatcaa cctttaaagt aattacttta
    22741 cctgtataaa ccctatcact actaatagtt ttttcttcta ataccatctt aaacctccat
    22801 taagtaatat gctgctgtgc ttgcagcttt gaaaaatgcc tcatcttgtt cataatttct
    22861 tcccatactc tttactttta gattaaaata gtctaaatcc tctttcgttt tattattatc
    22921 tatataaatt atattatgct ttttgtctaa accatttaaa ttgatttgct cttttataaa
    22981 gttcaatttt tcatcatcat atatagttat tggtatgtct acatttacat ttacaatttc
    23041 tttaaataca gtcatactat gatgtgaaat accttgatgt ctttctcgtt tgtcagcaaa
    23101 actaattctt ggaattgcaa ttgctcttcc ttcaagtttt tttacagcat caagaataga
    23161 gccttgttca atccctgtaa atccatattt tgttcctgtc ccagcaattc caggtcccat
    23221 actgacaaat actgcatccg cttttagtat ttcttttgct gtaattaatg cagtatatat
    23281 atttatacat tcataatctc caccaaacgc atttcctata gttattgtac tatctattaa
    23341 ttttttttct tttaaagtat ccacattttt acttaaataa attggaagag atgctccatc
    23401 agtcattata tacactaatt ttttatttgg attatttctt ttaaatgaag ctgcaaatgg
    23461 agttaacata ctatgaagag tccctactac aacagaaaga ccttctaatc ctttaaaatt
    23521 cgcaaattta tcatgataaa tactttcttg ttcctcaaca gaatccactt ttatttgaag
    23581 aggcgtatat ctaagtttca ttatatgtcc accttcagtt aaagtagatt ctatattatt
    23641 taaattagtt attacaaaat ggtatccacc tgtacctaag ctcagttcta ctgctgttgt
    23701 atttaaaacc acttcgtcac ctatatttat agttccagat atttttggat aattatatgc
    23761 cttttgtatt tctccattta tatttactct tatatcatct agagtttcag tttgacttac
    23821 tattgattca acaatcccca ctcttttgct tatcataata ctaccttccc aatttatcta
    23881 taaaatttaa tagtttattt ttttctatta tcttagttaa tgagtatttc tcagtgaata
    23941 tatgcataat aactacaaat attaaccatc ctaatctaat gttaaatgga tacccaaaag
    24001 aaatgagcat tccaatagat attccaagga cgtttgaacc agtatctccc atcatagccc
    24061 ttgcttttaa atcataatta aagtatgcaa gtacatttgg tactataagt aatggaagaa
    24121 cttgaacaaa tcctgtcaat gttaaaaata caattaccat tatgaataaa tatgctttta
    24181 ttgcccttcc tggtcttaaa tccaaaagat tcattaaatt agttgataga gctattatta
    24241 gtgtatttac tattatatca attatgtctt ttgatatagc aacagaaact ataagcccta
    24301 caaatccacc aaataaagct ttaaaacctc ctgttgtaag acttccttta aataaacttt
    24361 taaaatgccc ctttaaacca cttacatctc tatttccaat gacatcatct agtatccctg
    24421 caaaaaacat ggatatcata ccaaacataa acataaatat atacgctaaa ttcttaaatt
    24481 ctgtagtaaa gaaagcaagt attattccat tgattacaat cataggcaaa aatacaattc
    24541 ccatacttac tggtatcata tcttttttat agtttggtct aagtacattt ccatttatca
    24601 ataaattttt aaatagtgga attacagcat aggttccaaa taatccagtt aataataaaa
    24661 tggtataaag tatataatct ttcactaaga tattacctcc attctttctt tttttgtcct
    24721 aaaacctttt ttatgtgata atactgtttc cctctatgaa taaaaccttt taaatttctt
    24781 cctgtttcat tatgagtcat atttactaat acttctttaa ttttaaatcc atactttaat
    24841 atatcaatgg tcattccaac ttctactcca tatccaaaag gtatttcatc aaacttttct
    24901 aaaacttctc ttttaaatat tctttgacct gataaagttg catctaactc aacaccagtc
    24961 atctcaaaca cagaattttt agctaaacct tttacaaatc ccaaacctcc ttttctcttt
    25021 gcaggaggaa acttggctat tgtaacatcc gcctcaccat ttaatatagg tactattaat
    25081 ttttcaactt ctttagcaga acttcctaaa tctccatcca gaaaacctat aatatctgca
    25141 tttttcattg ctaacttgat accataattt aaagcatatc ctttacctct atttttatct
    25201 aacttaaaaa atttaatctt ttcattttct agctcagata caaccttagc agtattgtca
    25261 attgaaccat catccacaac tattatttca tttatttgct taatgtccaa tatgctttct
    25321 aatgtatatt ttattctact ttcttcatta taagctggta ttattatact tatataagaa
    25381 tccatttttt ctctccttaa aattatttct atttaataga tggcaacaat gaagttgcag
    25441 tatccaatct accaaaatta ccaactatat taccttgttg tagaagaatc gctagagata
    25501 tacttcctat accttcatca atattgtcta tagttgcaac tttgttttta gaatatagtt
    25561 ctacataaga agttttaact cctgtatttt gaacttctac taaatattta ttctctgatt
    25621 taagttttga aactacaaat ttttctattt tttcaaactg ttttgtactg tcttttgcat
    25681 catttccacc agctattaca acggaatcat attttagata tgtatctcca ataaaattaa
    25741 actttattac atctagttct tgaagatatg ttaaaatgtc acttgcatct tcctttttaa
    25801 gagtgtcaat tatataatta actgcatcat ttgcattttt tacatctgta cctagtttag
    25861 ttgacatttc ctttaacttt tctggatttg ttatgttttc ttttaatatt atattaaatg
    25921 caatgcttcc attagattta tttattatgt cttctatatt ttttgtataa tcgtcatttt
    25981 cattagcaga tattattcct atactcttac cattcagcga accagctaaa atcttatcta
    26041 catttttatt tataaaatta actgcctctt cataatctct atttacactt gctaagtcac
    26101 tgtcaagttt atcatttttt tcttttaaga tattaaactt atcatccaaa tcatttatta
    26161 tatttgcttg ttgttcactt aattgttgat tattatttaa attaaatcct actaacatgc
    26221 ctatacccaa agctataaat atagccccta tagtgactat ataatatttc atattaatat
    26281 gcatatttat cctcctaaaa tttacatctg taataatact ctaaacttta attgcattag
    26341 ttgtatgaac tgttgaactc ctggtgacaa tgatgcaact accaacacag gaaataatgc
    26401 tgttgctatt aatgcccata tgtactttat ttttaattta cttctgtata acaaattaac
    26461 gcctttagca tctataagct ttgaacctat ttttagtcta actaaaaaag tacttgccat
    26521 accttttctt cctttttcaa gaaaatcaat catatttgaa tgtgtaccaa ctgctactat
    26581 taactcagcc ttatactcat aggctataag catagctata tcttcactag ttcctggcgc
    26641 aggaaataca actgcatcta agcctaattc ctcaaccctc ttaagacctg gtgctcttcc
    26701 atctgtataa gcatgtacta ctatttcact agcctttttt aaagcttcat cacttacact
    26761 atccatatca cctacaatca catctggagt atatccaaac tcaattaaag cgtctgctcc
    26821 tccatcaaca ccaaccaata ctggctttac ctcttctata taagaaagca tagtacttaa
    26881 atcttctttg tagtcctgac ctcttacaac tatcaataca tgtttattag cataattagt
    26941 tttcactttt ggaatttcta cttctccaag tataaatcct ttttcttttt tagcataatc
    27001 tatagtatta tctataaatc tatccaattc tacagctaaa ttctcatagg cagcctttat
    27061 ttggtgtgaa acctcatact tgtctaaaac ttctcctgca cctaaaaatt ttccttttct
    27121 atatatcttt ccatctacaa cttctatagt ttctccttct tttaattctt caaataactc
    27181 ttctccaaca ttatcaatta ttagtatatt attttcagtt aatatccctg gacctttatt
    27241 gggataccta ccacttatag aaggagccgc atttatgaca agttttattt tagcttctac
    27301 taaagagttt gcagcaactt catctatgtc tatatgattt ataactgcta tttccccact
    27361 ttcaactctt ttagcaagtt ttttggtttt tcgatctact tttatagggg cctcgactct
    27421 catatttaaa cctccactat cattattaaa atcacattat attatagcat tacttaacaa
    27481 taaaataaat gttttaagtt tgttttgcat ctttggcatt tacaatacta tatttcatca
    27541 tttttttatt taacatattc cataatacgc ttaaaaatac aaagtttacc tgcatcaaag
    27601 tcaatattta tattaaaaaa taaaccactg tcagtttaca acttgtaaag acacatacta
    27661 tatccatagt ataataaaat tattatattg atatagtaag caaataataa agaaaatttt
    27721 tatatttatt aaaatagcga aacggtataa ccctagtggt tataccgttt cgctgcttgt
    27781 aatacgcatt tatagccaat gccttaatta aaaagcctta ctttttatgt cttgtttatt
    27841 taaccatact atgttctaat cttaatttat cagcaatcat tgctataaat tctgaattag
    27901 ttggttttcc tttagtattg tgtaccgtat atccaaataa ttgatttatt gtgtcaactt
    27961 ttcctctact ccatgcaacc tctattgcat gtcttattgc tctttcaact ctacttggtg
    28021 ttgtattgaa ttttttagct atacttggat ataactcttt tgttactgca cctaaaagct
    28081 caacattatc aataaccatt tttattgctt ctcttaaata taaatatcct tttatatgag
    28141 ctggtactcc tatttcatgt attatatttg tgatttctgt ctctatattt cctacattct
    28201 taacaaaatc acttctagtc atttgagtct cttgaactgg tctaggtttt ggctcaactt
    28261 gtgtaactct attagaaact agctctctaa ttctgtttat aaacacaaca aaatcaaatg
    28321 gctttactat gtagtaatct gctcctagat ttattgcgct ttgagttatc ttatcttgac
    28381 ctactgctga tagtactatt atttttggca ttttaggtat atccatagta ttcaattttt
    28441 caattacacc taatccatct agatgtggca ttattacatc tagtattaat aagtccggtt
    28501 gtgtcttttt tactaagtct aatgcttcaa ttccatcctt agctatgcct aatatatcga
    28561 tatcatcttc attagacaaa tactctttta atacctgaca aaaatcctta ttgtcatctg
    28621 ctaaaactat tttgattttt tccactaaaa atccccccat taaaaaacat cttcttatta
    28681 cagaaaacta aactttttac acaattgctt cctaattatc tactctaaag catattcgac
    28741 actccaaaat tatattcctc ctagataatt gataaaataa taaaattttt taatgcctca
    28801 cctacaattt tatcatttca tctataaaaa taccatatcc ttttttcgga ttatctctaa
    28861 aaacatgagt tattgcacca ataattttat tattttgtat tattggagct ccactcatcc
    28921 cctgtacgat acctcctgtg tattccaata acttgtcatc tactactttt attaccatat
    28981 ctctataatt tcctttatca tatactatac tttctatttt tatatcatag cttgttatat
    29041 ttttgttttt atcctcaaaa agaattactg catctcctat ttttacatct tgcggtcttc
    29101 caacttctat taattgcttt tctttatttg ctacattaaa ctctttatta tggttttctg
    29161 taatattacc acttatacct aactctgaat tatttgagaa attacccatt aaattgctgt
    29221 cattaaaatc tccttttatt ttacctactt tttcattact agcttttact atttttaatt
    29281 gttctggctt atatatatat ccttgcttta tctttaatag ttcattagta tccgaatctt
    29341 ttatggcatg accgattgct ttgaactttt ccatactagg gtcgtaaaaa gtcatagttc
    29401 caattccaga tattttatct cttacccata atccaagttt atacttgcca ttttcttttt
    29461 tagtctctat tacttctgtt ttatacttat tttttctctc aaaagtcact tcaactttac
    29521 tttttttaat cttattcaaa atctctgata catcttgact attttttatc cttttattat
    29581 ctatttttac tatattatca ccgatttgta tgcctccaat atagtctaca tcctcttcct
    29641 catatcctaa gaccaataca ccatctgtat ttgcttttac tccaattata tttcccatag
    29701 gatatacaaa ttttttatca tgattcttaa ttgtaaaagc ttctatttga gtctctttat
    29761 taacattaca atttttatta aaaattataa ccatggtaaa aatcgataca gctcctaata
    29821 ttatccaaat atttttgaaa tttttattta ttttgttcat atatccatct actcctatgc
    29881 tgtattatta tgtatttata attccttttt cctgagaatt tattcattta aaaagtttat
    29941 ttaaaatctt aataagtgat ttttaataca taatatgata gtattagatt gtaacaaaaa
    30001 gtttgaaggg cggtaatatc ttgaaattaa atgtaagaat tgcagacata aataattggc
    30061 atgatttagt tagtttgtct gtagataaaa gtcagttaga ttatatagaa agcaatgcac
    30121 tttctattgc tgaatctaaa tttataacag cttgggtacc tgttggaata tatgatgaaa
    30181 attctttaat aggatttgct atgtatggtc gtttagaaga tgatagagtt tggcttgata
    30241 gatttatgat tgattcaaaa tatcaaggta aaggatatgg aaaagcatca ttagattttc
    30301 ttgtaaatca tcttaaaaat gaatataact gtgatgaact atatcttagt atattcgaag
    30361 acaataaaat ggctattaag ctttataaag attttggatt tgagtttaat ggagagcttg
    30421 actatggtgg tgaaaaagta atggtattaa aatctaattg atattaagaa aaatatacat
    30481 atatcaagga ggtgaagtca ttatataaac atgtttatat aatggcggat aaaatggctc
    30541 aaaatataac tttacaattt gttgaagaaa aagatttaga aaaccttgaa aacgtaaaac
    30601 ttctatttac tgaatattca aattctctaa atatagactt atgttttcaa gactttaata
    30661 atgaattaaa aacacttcca ggaaaatata aaaaaccttc aggctcattg atattggcat
    30721 ttgttgatga aaatttggca ggttgtgttg ctttaaaaaa acttgaaggt aaaatatgtg
    30781 aattaaaaag attatatgta agaaatcaat ttagaggatt aaaaatagga aaaatactat
    30841 tggaagaaat cattgaagaa gctaaaaaat ttggatatac acacatgaga ttagatactc
    30901 ttccaagcat gaaaagtgca caaggattat atgaaaagtt tggtttttat gatatagaac
    30961 cttatactta taatccaatt gaaggggcta gatatatgga attaaaatta taatttttta
    31021 atagagtata agtaaaacta ctacagtttt atttatactc tattttattg aacaaatcta
    31081 tttgaatatt tatttaaata tgtatttatt tttctaaatc ttgtaatccc atagttatat
    31141 cttcagttat atcctttgta tattctactc cattattgta tgtaagttta gctttaatat
    31201 aaattatgtc atcaatatcc cttttaggaa aacttacttc ataattcact tgatttctat
    31261 ttgaattatt agttttgcca tcatctaagc cttcagctaa tttggctttg tatatagtgt
    31321 ctttttttcc ttcatttaca ataatatcta ctttttctaa tctaatatta tcataaactt
    31381 tattttttga cttttcactc tcatgattga aaagattact attttctact atttcaataa
    31441 agtattctct attatctctt atcccagaat taaatatggg ttgttcaggc atataatcag
    31501 atttagtcaa tttttgcaca tcagaacttt cagatatagc tccacttgta actactttat
    31561 agtcatattc acttcctgta tttatcttaa tttcacatgc atatgataat tctccatgtt
    31621 ttgtcatctc agtttcattc catttatcac tatcttcttt atacataaaa aatacttttc
    31681 cattttttcc aagtttactt aattgaacat ctacatcaat aacacactct tttttctcga
    31741 ttttttttac ttttaagtca atactctttg ttatataact ttttgacatt tcttcattta
    31801 tagtattact aatatccgat ttagtactca taatctcttg tgacaaataa tctaatttat
    31861 tactacaact ttcaatattt ttattaatct cacttactgc taccacaata taccataata
    31921 aaataaaaat tacaattgta aaaattaagt gcatagtatc ttttttattc attttatgtc
    31981 cccctcacta ctaccttaat aaataatatt atacttaagc atttagaaat ttcaaagtta
    32041 caaatttata caaattttct tctattttta aatctacttt tcttcaatat aggcactaga
    32101 tattttaaaa taatttcatc ataaaaaata gatgtaaagc atttctataa aaattcttta
    32161 cacctattaa aatgcttgtt tttcactaac attttttagc caactcaata atttcacttg
    32221 catgttcaat agttttttct gttatattgt tacctgctat aagtctggca atttcatttt
    32281 ttcgttgaga ttcatttaac ttactaacat tggtaaacgt cctattattt gaagtatctt
    32341 tctctataca ataatgagtg tctgcatttg cagcaatttg aggtaaatga gttatacata
    32401 ttatctgttt tttctttgct atatcactca atttctcacc aactatctgt gctgctatcc
    32461 cacttattcc agtatctatc tcgtcaaaca ctaatgtatc aatatcatct atatcagcca
    32521 atatggtttt aaacgctaac ataaatctgg acatctcacc acctgatgca actttatata
    32581 taggcttaat atcttctcct aagttaaaag atatcataaa ttcaatatca tctactccat
    32641 ctaaagtaaa tggacctttt tcaaaattaa ccttgaacat tacatttttc atatttaagc
    32701 tttttaattc atcaagaagt attttttcta aagtagttgc tacttctatt cttgctttag
    32761 tcaatttact ggcttttatt tttaaatctt cttctatatt catcagtttg cttcttaact
    32821 gttcaactct ttcatctctg tttaatattt catctaatct atctttaatt tttccataat
    32881 actcaaatat atcatctata ctgtctccat attttcttct taagttatta atctcgtcga
    32941 ttctaagctc aatctgctct agctcataag gttcaaagtc tatattatct ttgtaatttc
    33001 ttatctcacc agatatgtct tgtaactcat acatgattct ttctacagta tcactatatt
    33061 cacttaaaac actgtcatat ttagatatgt cattaagttc cttagatgca agacctatta
    33121 ggtcaataac attatactca ccattatgta acttgctata actcgaattt agattattat
    33181 atatcttttc actatttcta taaacttctc tttgttttaa taaatcttca tattcattct
    33241 tatttagatt tgcagcttca atttcattta tttgaaatct taataaatct atttctcgtt
    33301 gaatttgcat ctcatcttta ttttctgtca agcaatttaa agcttttttt acttcactat
    33361 acttatggta cacattttta taagcaattt taaactcttc caattcattt tctccaaaaa
    33421 ggtctagaaa ttttaaatga gtatctttat taaacaaagc ttgattttga tgttgaccat
    33481 gtatatctat aagtgtagat gcaatttctt taagaagaga cactttaaca gtccttccat
    33541 ttactctagc agtactctta ccatctgagt atatcaacct agttattacc aataaattat
    33601 catcttccat acttatatca ttttcttcta atattttttt aagatatcta ttgtctgaaa
    33661 aaaatacagc ctcaacaagt cccttatctg ttccttttct taaaaaagac ctatcatatt
    33721 tatcacctaa acaaagtcca agtgcatcta ttattataga ttttcctgaa ccagtttcac
    33781 ctgtaagtat atttaagttt ttatcaatat tcaaccttag ttcttcaact aaggcacaat
    33841 ttttcatata taattcgagg atcaaatcta agcccccttt taacctattt gtctaaatta
    33901 tgagaagctt caacaacttc tactattttg ttattgtatg tctcaccatc aaattcatat
    33961 ccttcatttc catttctcaa atgaattaga tattctatat taccttcagg acctttaata
    34021 ggagaaaaat ctaaccctaa aatctcaaat ccattttcga ctgagaaatc agaaatcatt
    34081 tttataactt ctatatgtgt agatttttct ctaactactc cttttttacc tactttttct
    34141 cttcctgctt caaattgagg tttaattaaa gcgacaactt ccccatcatg acgtactaac
    34201 tcctttgcct ttggaagtac taactttaac gatataaaag acacatcaat tgacgcaaaa
    34261 tcagcaaact gctttgtatc ttctattgtc acatttctta tattggttct ttccatacac
    34321 acaaccctat catcttgtct caatttccat gcaagttgac cataaccaac atctatagaa
    34381 aatactttta ttgctccatt tttgagcata caatctgtaa aaccacctgt ggatgcccct
    34441 atatccatac atacctttcc atcaatagtc aaatcaaagt ttttcattgc tttttcaagc
    34501 tttaaaccac ctctactgac atatggtatt ggatttcctt ttacttctat actacaatct
    34561 tcttttactt ctgtaccagc cttatcacac ctttgattat caacaaaaac caatccagcc
    34621 attattgctt ttttggctct ttctctactt tcaaagtacc cttgttctac taataataaa
    34681 tctattcttt ttttcataca attacctttc tgttaaaagc tactttaatg ataactaaag
    34741 tagcttgaag taacacactt gatatttatt ctaattgata aattctatat tttatataaa
    34801 ttttaattta caatatctac attagatttt tactcaataa ctaatttcct tattttatca
    34861 gcaatacttt ttggcgataa tcctacaaaa tcatataatt catctatatt gccatgtttt
    34921 acaaattctt ctggtattgc tatattaagt atatttacgt tatattcatt atctataata
    34981 aacttattta ttctacttcc aaatcctcca gttacaatat tatcctctat agtaactaca
    35041 tttttatgat tttttaataa tgcttttaac ataccttcat caattggctt taagaatcta
    35101 gcattaacta ttgtcggatt tattccttct cttgataata tttctttagc ctctaaagca
    35161 tgttttacca tacttccaat acaaagtatg actgtatctt gaccgtcatc taatacctca
    35221 tatttaccca gtacaatctc tccatactct cccttatcta ggtaataact acttcctctt
    35281 gggtatctaa ttgctagtgg acaatctaat tttaatgaca aatccatcat aagctccatc
    35341 tctcttgtgt cttttggagc cattactaca atatttggaa tagaatttaa gtaacttaaa
    35401 tcaaacatac catgatgagt ttctccatca tttccaacta atccagctct atctataaga
    35461 aaagtaactg gcttttttgt tatgcataca tcatgaataa cttggtcata tgccctttgc
    35521 aaaaatgatg agtacacagc aaagtaaggt ttcataccat tttttgcaag acctgctgca
    35581 aatcctgttg catgttgttc agctatacca acatcataat atctttttgg atatgcactt
    35641 tcaaacaggt ttaaccctgt accagatggc attgcagctg ttattgctac tatattttca
    35701 ttactattag ccatatcaac aagtttttct ccaacactaa ttgacataga cttaactttt
    35761 gcagatgtaa cacctgtctt tatatcaaac tttgatactc catgatattt atcaggttgt
    35821 tcttctgcaa atctgtaccc ttttcctttt ttcgtaatta catgtaaaag aacaggccct
    35881 tttttgtgtt tagcttttct caatatatct attagttctt tagtattatg gccatctata
    35941 ggtccataat atcttatacc taatgaatca aaaaatgaac agtcctgagg agaaaagcta
    36001 tacattagtt tatctttaaa tctatgtgca gtcttagata aaatttcacc tgtttgtgta
    36061 acatttaaaa ttttatcaac ttcatctgtc attttctcaa ctgttgagtt tcttataata
    36121 cttgacagat atttagacat tcctccaaca tttttatcta tggacatctc attatcatta
    36181 aggattacta tcatattggt atctatatat cctaattgat ttaaagcttc aagtgccata
    36241 cctcctgtta tagaaccatc tcctatcaca gatataacac tatagttttc tttttttata
    36301 tccctagcac aggcaatacc tgtagctata gaaatagatg tactgctatg tcctgtatca
    36361 aaaatatcat gaggactttc attctccttt ggaaaaccac ttagtccatt aaactgtctc
    36421 aaagatacaa aacaatcttt tcttccagta actattttat gaacataaga ttgatgccct
    36481 acatcccata caatcttatc tttagggcta tcaaatactt tatgaagtgc taatgttaac
    36541 tcaaccactc ctagattaga agctaagtgt cctcctgtct ttgaaacaga ttttactaag
    36601 aactttctta tatcctttgc aagtaaatcc atttcttcta tactcatatt ttttatatcc
    36661 tttggagaat ttactttatc taaatattta tacatattat cctcaccttt attctgtaaa
    36721 ttttcaattt acatcaatat taaagctgtt actattccaa gtaaagctcc aaaccaaact
    36781 tctagtggtg tatgacctat taattctttt aatttcttct gctctatatg ctttccatgc
    36841 tgtatatctg ccaccatttg atttaatata gtagcttgtt taccaacagc ccgtctaaca
    36901 cctgctgcat catacattat aattaaggca agcacggtaa ttatagcaaa atcagtagaa
    36961 ttaaaccctt tttcaatacc taccactgta gctaaacttg taacaaaaga actatgggaa
    37021 ctaggcatac ctcctgaaat aagtattctt gataactcaa ttcttttttc cttaccagta
    37081 aatattttta taaattgtgc taagaaacaa gcaatcagac ttattcccaa agccccattg
    37141 ttaaaaatct ccgaaaaaaa atccattttt ccctcctcga ttttagctgt atattttagt
    37201 attctctatc tattatatat tcagccaatc cctttaaaaa atctacatca tcagataatt
    37261 tttctatact tttctttgct tcatcaatca aattatgtgc aatttcttta gatttatcta
    37321 aacctaaaag agatgggtat gttgacttat gattttctat atcacttcca acctttttac
    37381 ctaacttagc ttcatctcct actatgtcta gtatatcatc tactatctgg aatgataatc
    37441 cgatattttt tgcatattta gttatttctt ccatttgttc agaatttgct ccacctatag
    37501 tagctcctgc tctcatacag cctaccatca ttgcagcagt tttattcata tgtatataat
    37561 ctaatttttc ttttccaatt tgtttatttt cgctttctac atctactact tgaccaccta
    37621 tcattccata tataccagca cctttggcaa tttcatttat agcttttaga tacttttctg
    37681 gattttcttt attgattgag cctgcaagca ttacttcaaa agcatagttt aacaaagcat
    37741 ctcctgctaa aatccccata gcttctccat atactttatg atttgttggt cttccccttc
    37801 ttaaatcatc attgtcaaga gctggcaaat catcatgtat tagtgaatat gtatgtatca
    37861 tttcaattgc aatagcaaaa ggaatagctt catcttcatt acctccaact attttacaag
    37921 cctccaatgt aagtattggt cttaatcttt tacctccagc acttaagcta tagttcatag
    37981 cttcaataac agttttttga tacccttctt ctttaggcat atattcttta agtacttttt
    38041 ctacaaaact tgctttttct tttagacatt gtttaaattc caattttatt cctcctctat
    38101 tttaaagtct tcttctattc ccaattgatt aaatttactt attttcaatt tagcatcatc
    38161 taaaagctta ttacaatgtt tataaaggct tataccttct tcatataggc ttaaagattc
    38221 atccaagcta gcatttttag attctaattc acttaaaata ctttctaatc ttttataagc
    38281 ttcttcgtag gttaaattca tactatccct ctttattttc aattttatct atcatacatt
    38341 ctaaatttcc atcttttaat actatatcta tactatcctt tatttttaat ccttttatac
    38401 tatttattac ttttccattt ttttgagtta tactataacc tctatccata gtagctaatg
    38461 gacttaaatt atggagtaat gctccaattt ttactaattt ttcatcttct aattttaaat
    38521 tattttctat tccaaaaatt attttatcat atattttgtc taattgtata actttatctt
    38581 ttattgtgta cgaatctaaa tagttattta tcttattaaa tactgtttct aacctatatt
    38641 ggtctagctc tatttgattt gtaagagact tactcatcct actttttatg tttccaagtt
    38701 tatagtttat atcatccaat gatggagtag caatctcagc tgctgctgat ggcgttgggg
    38761 ctctcatatc agacacaaag tcacaaatag taaaatccgt ttcatgccca actgctgata
    38821 ttatcggaat ttgagaatta aaaacctctc ttgctaccat ttcatcatta aaagaccaaa
    38881 gttcttctat cgaaccccca cctctaccaa ctataagtgt atcaacattc ttcatatgat
    38941 tgaaaaatct aattgcttca cagatttctt cagctgattt atctccttga accgttactg
    39001 gataaagctt tatattaact ttcggatatc ttctttttat tacatttatt atatctctta
    39061 taacagcacc tgttggagat gttataacgc caattgagtt tggcatttta ggtataggta
    39121 tcttgtattt agggtcaaat aatccttctt tattaagttt ttcctttaat ctattaaact
    39181 ctatgtgtaa atttcctatt ccctctattt caatttcatt aatgtataat tgatacgcac
    39241 catctctttc atagactgat atatatccat tagctataat ttttacacca ttatctaatt
    39301 ttaaattgcg attaaaatta cttttaaaaa ttacacagtt taactttgat gtttcatctt
    39361 taagtgataa atatacattc ccactactat gaaccttaaa attagaaatt tctcctttaa
    39421 ctttaagatt agaaagtatt gggtcgttta ttaaaattct tttaatatat gagtttgctt
    39481 cacttatatc taaagctctt agtttcatac tctttctcct aaaaagttat tcaatcctat
    39541 tatagcacac ccgacagcat tatcagttga atattgtggt tctgtaaaat aagcttctat
    39601 atgctttttt cttaacttca tgcttaattc tctaagaata tacttacttg cagaaactcc
    39661 accagcaaat actacttcat ttacattata agtttcacat aaatacacta aagatttaaa
    39721 catatttcta actactgaat ctaataccaa tttagatata tattcttttt gattagtatt
    39781 atctccatta tcatttataa tcttatttac ctgattttct aatcctgata aattcatata
    39841 cccatctctt acagaagttt tcagaccact ttctatttta agattacaat ttaaagcatt
    39901 ttcatccaaa tactttcctg aaggaaattt atatccaagc ttaattccta ctctatctat
    39961 aagttgacca aagctaatat ctttacttcc tccaattata tctatattat atccaaaatt
    40021 attgtataac ttacttttat catctttttt aatacttatt ttggcaattt tacctaaatt
    40081 agtatcacat acattgtgat gactatcttg tttgcttgtt aaaagtatct ctgtagtacc
    40141 accagacata tgaacagaaa taaatttatt attatttttt aatttactat ttaataaact
    40201 tgcttcaata tgattctctt gatgagtagt ctcataaaac ctacaaccat atatactaga
    40261 caataatttt ccaaaattat gacctacatt gaatacaggc atatatgagt tttcaacagg
    40321 tctcggtttt tttgatgagc aaactccttc tacattaaac ttatctttaa aagattttat
    40381 cctatcacta agaatcccta aattattgat atgttgaaat acagcttcac tttgccttaa
    40441 accttttgaa ttatccctta cttctaacat tattttttca ttgaatataa ctttcttatc
    40501 taaagagata gctgctatag aagtagtata gcagctagta tcaattccaa ttattatatt
    40561 atttcccaat ttcatcaaca acacttccca atataccatt tataaattta ggagacttat
    40621 catcacaata tatttttgca agttctactg cttcatttat tgatacttta ttaggagtgt
    40681 ctaaataaag tatttcacac acagacaatc taagtataga aacatctacc tttggcattc
    40741 tatctactgt ccagttttta gcatgcttat ttattaactc atctattttg tcatgatttt
    40801 ctttcaatgc tttgcatact gtatttatat attttttgtc tataacatct tcaatttcag
    40861 tatcttctaa ctttaaattt gtattttttg agtattgaag tgcaagttct ttatatctat
    40921 ttataatatg ttctgaatta tcttttaaaa aattatctac tttatcttct aaagtttcaa
    40981 aatcttcttt attaatattt atttggtata taagtttcat tatatattct cttgttgtac
    41041 tcttttgtgc cctatctttt ttcatcaatc aaaattctcc tttaagttta attatccata
    41101 taaaatcaat taccagcaaa aaaccctctg acttttcaga gggctaatat taatttttct
    41161 tagttgcttt tgcttcttct ttatcaactt tatccttctt aaagctgatt ccttgaatgt
    41221 gtatatttac ttgagaaacc ttcagtcctg tcattgtctc aacagtattt tttacatttt
    41281 cttgaacttt aaaagctgta tctggtattg acattccata ctttatcgta accattacat
    41341 ctaaattaac atcctcttct tcgatttgta tttttactcc attatttttt aacaacttat
    41401 ctgttaatgt tgctgtagtt tctatgcctt caacttctaa tgctgctaaa ccagctattg
    41461 tagctattac atcattagat atttttactt gtccaaattt attatcttcc atattaaaac
    41521 ttacctcctg attttaagga actattttta taagtataat aataccaaat acaagtctac
    41581 tttgcaagaa aataacctca gttaattctg aggtttatac tttacttatt actattatta
    41641 tttgtaagtt taatattttc atacttcaca ttggcttgtt ctgcaactaa atcaaatatt
    41701 tttgctgcat ctttcttttc taatttagct tcatttacaa ctacattaac tttgttatcg
    41761 cttatataaa ctaacgcttc ttcataccct tttgtactca aaaggttttc tatttgaagt
    41821 tctttttctt gaattttaac tatatttaat ttcatattag aagcttcttt tctagattct
    41881 tctgttgtag atggattatt tatcatttca tttaaatctt gaactaactc atttctttgt
    41941 ttttctctat tcattttcat atctaaaata taagatgcct ttttcatatt tttctctgat
    42001 gataattgag cttttatttc cttacttgtc tcagttgcct tttcttttac tttactagct
    42061 ttgctatcaa ctatatcaat atcagcactt tccttaccat cttgtttatc tacattacta
    42121 gaatcctctg tcttactact atcactctca tcagtatttt tttgcaactg tgcttcttca
    42181 tatgccttaa actcttttga tgtttctaat aaagatttct tacttagttg ataattcact
    42241 gttcctacta ccactaacat tgcagttaaa gttattatta caaatcctct tcccttataa
    42301 ttaaacttca ttcatttatc cccccggtta tatgtattta tttagaatat atttctactt
    42361 gatgaccagc tacttgtaat gatgtttgta ctgcactata aagtgtctct ttaacacttg
    42421 ggtcacttgc tccacttgct accactatca ctccctttat ctttggctct gtagttttta
    42481 taactacagg gtcacttgaa tttgaagtta tcattgtttt attttcacta gaagtcgtaa
    42541 ctgttctttc tccaccttgt gcatcttttt cctctgttgt ttctgttgta ttatttgaat
    42601 taaaagcagg ttgtatttct tcacttgatt caaatgtaac cattacatca acgtctcctg
    42661 caccatcaat tttagatagt attgctgtta attttgactc taaatcatct ttttcttgtt
    42721 ctttagtgac ttgcttttca gcatttttat tagtctctgt ttttccaact tgtttatcgc
    42781 ttttgctact aggaaaacaa gataataata ctaatgaaac cacacatatt cctgctatag
    42841 ttattagtga atataccttt ctcttatctt tgtcatttaa gtttttcaac attctcccaa
    42901 ctcctattta tcaatttgta tatcttctat agaaacatcc agcaccttta ttaagtcgtt
    42961 ttttaatttt tcttcattta ggttcaaccc atactctgta ccttttttga agacttgttt
    43021 agaattttct ttgtcattag agtttatgtt ttcttcctct cttttagtac tattattttt
    43081 attttcttca ttggaactgt tattactttt tgcactatta ttcttttctt ttatttttat
    43141 attatttata tttgccccat taagctctat atcttctaaa tcataaccat attcatcaag
    43201 ttttaattta agtacttctt ttaacccatc ctcatatccc ttggatagac tattatttcc
    43261 agtctctttt gccaaagcat ttgtactatc tacatactgc ttgttgtagt ttcccataga
    43321 ttttaatatt ctatcttcta aactcatatc ttttgaaaaa aatcctacta ctggagttat
    43381 tacaataaat acaaacataa agtttaaaac taggttgaca taaggtttta tcttagaact
    43441 tggtaaaatc atatctacta tatttactat aaatgctcct atcaaaacac taactatcca
    43501 tgcctttatg ccctctaaca tagcatcctc ctctctaaaa acattagatt aaatgtaatt
    43561 atttttcact gatatataaa ttacccttga cttacgacac ttatcgaggt caagatagct
    43621 acagttacaa agaacattac tgttatagca attactgatg ctagcattat tatcattaaa
    43681 tttgccactt catttaaaaa attagatatt ccatcctctc caacaggctc tacaattatt
    43741 gctgctaatt tgtacactac tattactgat aaaattttta ttactggaag taagcaaatt
    43801 ccaacaagta agataagtcc tattcctcca aatatatttt ttataagctg agatgaagat
    43861 aataaaatat ccacagagtc agatacaaat ccacctacaa caggaataaa attacctata
    43921 gcaaatttag cagtctttac actgaattta tcaaaactgg ttacatacaa tccttgtatg
    43981 gatacaagac ctaagtaaac agtaaacata gctccaatag aaacataatt tatttgtttt
    44041 acaaaggaga aaaatctctt tagccttata ttttttgata aattgtttat tattaaaatt
    44101 ccaaatgcaa cagtaataga tacaaataga aaatttttaa aaaatacatt tataaatgtt
    44161 actcctccta tgaagatagg attcaaagta gtcgacgtta ttgggaatcc aattaaaagt
    44221 aaaaatgtta ttaatattgg cattataact tgcataagac ctacagtatg gtctattgca
    44281 tcatagcaaa tctgtaatac atctttaaaa ccaataagtg taagtgatac cattgtgata
    44341 aatattatat atgttgctat ttgacttact gcacctgatg aaaaagagtt ttccagactc
    44401 tttaaaatag atgataacag agccagtacc aaaattactg ctactacctt taaacttgct
    44461 ttaaattcat caaacatcaa tatcttcaat ccatctttat tgaataaatc taagatattt
    44521 ttttctccac taattaaatc ttttacaaat gattttaaat taacatcatt aataactatt
    44581 tctttattta tatagtcttg aatctcattt atatctagct tgtctaattg accatctata
    44641 tacttatcta tgctattttt tgtttcacca tattctttat cttcactact tggtacttca
    44701 ttagcaaata tcataatagc aaagatattt acaaaaaaga aagtaaataa aaaacctata
    44761 atcattggta aaaatctttt tttcataagc aaccatgcct ctcttcactc tataaacctc
    44821 aatacaacga aagctctcta atatacttat attcattcca agatacacat ctatggaatt
    44881 atattcacca ccatttctac aatggacaaa agtataggga aagacattga cataactatt
    44941 attttacctc caaattctag ttttgaagca atgtttcctt ccccacaatc tttacaaagt
    45001 tgtatcgcaa attccattaa gtatgctatc ccaattaatt ttattattaa tgatatatac
    45061 atagttggga tgttagcctt gttagccaaa tcttgtatac tatctactat aaaatttagc
    45121 ttaaacataa ctgacaatag tattattact ccagttatta tagctatgaa atttgctatc
    45181 tctggtctat cttttttaat tactaaacag agtgtagttg aaatgattgc aattcctatt
    45241 aattgcatta tttccaaatt actccctcct ctttagtaaa gttgaaacat tgttcttaca
    45301 gtattaaaca agtcacttat ttctgttatt accataccca atacgattat tacacctgct
    45361 aatgtagtaa gacctgccca atcttttcta tctgtttttt ccaatatcat attcaatact
    45421 gatattagaa taccgacacc tgcaaccttt aatatcaatg atatttccat aataaacctc
    45481 cccatattaa atcaatataa tacatatacc tatacctatg aatgtcacta attttttata
    45541 caatacgcct tttttgttta tatcttcctt tgtctcatag gtttgttttt tcaaattttc
    45601 tatagataaa tctatcattc tttgttgtga ctctatatcg cttttcccta aagtaagtat
    45661 tagatttttc agttcctcaa tttctttatt gcctagataa gtttctttac ttaagacatc
    45721 aatattttct gatattatta tttccaaagt tttactttgt tcattgtgaa gtccttctga
    45781 tatttgatag aaaaatttcc aaaaacaaaa ctctttattt ccacctatcc tattaaagat
    45841 ttcttctaat gtataaagtc caaaagataa atccatcctc aaaatttcta aaactcttat
    45901 taaatcgttt aattgtttat gtctacgagt ataagttttg tatatttgtt cacctatcaa
    45961 ataactactt cctatcaaga aagctataat aattatttta atttgcaaaa taccatctct
    46021 tttcttctaa atcataaatt ttttcaattg ttcctgctcc tctttttgca gaaagaatta
    46081 taaccttttt aaataactct ttatccagaa gtctatttaa ttcttttcta ttttgtatat
    46141 cctctattga atctccatgc acagtagtta ttaatcctat acctccattt aatgctgtgt
    46201 ataatgcctt tatttctttt tcacttccaa tttcatctgt cacaataaca tttggtgaca
    46261 tagaccttaa aagcattgta atacccaagt cttttgggca agtttctatt atatcagtcc
    46321 ttattcccac atccatttgt ggaacaccta gataagctcc tgctatctca ttacgctcat
    46381 ctactaaagc cacttttaaa cctttaaatc cataatcttc attaccatta cttaaatttc
    46441 ttactatatc tcttattaaa gttgtttttc cacattgagg tggtgatatt atcaaagtat
    46501 tattaatctg attttttccc tttatgatat gacttaaaat cttatccgag catccaataa
    46561 tttcccttga tacccttata tttaaagatg atatatgctt tatatttttg acttgtccat
    46621 cttctactat tgcttttcca actaacccta ctctatgacc tcctctcaaa gttatgaatc
    46681 ctttttttat gtcatccata aatgaatgta ttgaatattt acatattatt tgaaaagttt
    46741 gctctacatc ttctcttgtt actacatatg agttttgttg atttaaatca agtgtcatag
    46801 ttttttgatt gtaaaaataa tctttagagt ttgcatttag tatcaatggt ttttgtgagc
    46861 gtaacctaat ttcttctatg ttcagattat tgtttgagac tttttctacc ttttctctta
    46921 tagttgtaga aagagagttt attatttcat cagaaagttt attcatctct tgtcctcctc
    46981 ctttgtttat ataattctat ttataaagga caaggaatat aaccaaaaca tctatatttt
    47041 tttaataatg tttataaata aaaaaagtga acccatttat cttggattca cttagtaagt
    47101 ataatataaa ctactattat taatctttat aatatattta ataagtatta acaaaaagac
    47161 acttcaatca tgaagtgcct ctataacatc tacatttctt ttattagccc tttcttataa
    47221 gccattaaaa gtagttttaa atcttctatt tcctcttgta tctttattcc ttcatcagta
    47281 tctctcacca tttttctctt tgccttatgc tctactacaa cagttgtcga taagatatca
    47341 ctttcatttg caatggcttc ttcagcagaa ttaaatggtt catgcgatac taattgcaaa
    47401 gttctagaat tgtatatcaa agtgtatcca gctataccag tagttttttg gtaagcccta
    47461 gaaaaaccac catctataac gagaatttta ccattagctt ttattgggct ctctccattt
    47521 ttactctcca caggaacatg accatttatt atatgagatt catcaagttc taaatcaaat
    47581 tcttcaaata atcttttaca agccatctca ttttctctaa gtttaaaata tgggttctta
    47641 ttttctttat gagtctcttt ttcagctata aagtatcttt caaatgtagt catatcatct
    47701 ttaccaaata atgatgaaca tttcccagtc cataaatacc acataatatc catgccatac
    47761 agtttttctt ctgccttatc tttaaagaaa aatccttctc ttgctagaga ctccatctta
    47821 tccataagag ccttaccttt atactctttt cccattatat tcatagacat aaagcttcca
    47881 tcttcattta acggtacaca tccatgaatc agtaaatttg agttagcctt taaatatata
    47941 cttcctttag aaaacaaaaa tgaaacatgt ttttgtagtt tttcactacc tctaaatgaa
    48001 gatactaatt tatcaataac atttctttct tccatagtta atttatatgg gtcttttttg
    48061 tctattgtag gtaaataagt atcttttaat ttatatgttt taccttttaa attaatcgta
    48121 ccttcatcat agtttatcat attaagcaag agtctatgtt ccatttcaaa ttcaggtctt
    48181 cgtctgataa cctcaccttc aagcttaaat tgaattatac ttattgcttt gtgcattttt
    48241 gccattaaag acttttctgt tgttgttaca ctttggtcat taacctttgg aataaattct
    48301 ttacaagggt catctttata catttctata gcaaaagtgg ctaaaggcaa tagatttatt
    48361 ccatatatgt cttctacaat gtctaaattc gcatatctag ctgatatcct cagtgcattt
    48421 gctatacaag ttttttcacc tgaggctgca cccatccaca atatatcatg atttccccat
    48481 tgaatatcta cacaatgatg ttcaataagc ttatcgacaa ttatatctgg tcttggacct
    48541 ctatcataaa tatctcctat tacatgaagt ctatctacaa ccaatttttg tataactgta
    48601 gaaatagcaa ttataaactc cttagctatt cctatgtcaa ctattgtttc aactatactt
    48661 ttataatact cttctttatg ttcactttta acatgctcat gcaaaagttc ttctattatg
    48721 tatttaaaat tttctggtaa cagttttcta actttagacc tagtatattt gctagaagca
    48781 tatttacaaa gttctataag tctataaata tttattctat aaaaatcatc tatattttcc
    48841 tcttgcttaa ttattaggtc taacttttgt tcaggataat atacaagagt tgctaacatt
    48901 tttttttcgc tgtctcttat tgtatttgaa aacaattctt ctatttttct ctttattaca
    48961 ccagaaccat tttttaatac atgtacaaat ggttcatatt caccatgtac atctgttata
    49021 aaatgctctg ttccctttgg aagatttaat atagcctcta aatttattat ttctgtactt
    49081 gcttttgata tacttggata ttgttttgat aataacttta aatacttaag cttgctgttt
    49141 aaataatcat ctgatatttt acacagattt ttcataattc gtcctccaaa attatattaa
    49201 gttatattct tttttaatta taccatactt aatatacttt tttcgagata aaatgtacac
    49261 taattatatt cccaataaaa gtgacattcc tattaaatca gtataaacac cattataata
    49321 acattctttc tttagtatgc tttctacttc aaatccaact tttttgtata atcctatagc
    49381 attataattt tcttcattag tgacaagagt tatcttcttg gttattccat ttgatttaca
    49441 ccattctata aggtctaaca taagcctttt acccaatcca attccccaat atttttcttt
    49501 tacaacaatt cctaatactc caacatgctt tccttttgct ttttgattag aatcaatcgt
    49561 tgcaatccca actatttcac catctataaa tgcaatcagt ttaacagaat tatcagatgc
    49621 ttttgctgat tctatagcat tttcttgttc ctccaaagat attttatatt catcctttcc
    49681 aaatgacaga aaatgagttt ctccacccac ttcattataa aaatctataa tgctttgagc
    49741 atcttctctt acaccttctc taataagtac gtctacacca ttttttaatg ttattgttgg
    49801 cataaattta cctcctaata agttttttgt ctataaacat aatactattg ttcttctgtt
    49861 gttacaatat ttttcattta ttgataacaa tataaggcta tattaaaata aaaaattaat
    49921 aatattttaa tatagccttg tagatactta tttgtattta attttctgcc aatgtctaat
    49981 tttaactcaa taaattgtta taacataatt aaactatttt ctttaaattt tcaccataga
    50041 tttttctatt ataagacttc attataaagt ataatggtac tccaattgcc aaagctccta
    50101 atcccataat taattgatgc atagatgctt ggaataacaa ccatgttcca acacatacag
    50161 caattagagg aatcactgct ccaaaaggag ttttaaaagt acctactaat tctggtcttt
    50221 tctttctaaa cactaatacg gataaagatg ttggtatgta ttgtatgaat ctagcaactg
    50281 cacttattgc tgctaattca gcaaaacttc cagatagagc tattggtata gtgattaaca
    50341 tagtagctat tatcgctaca tatggtgtac cttttttatc ttttcttgca aatattctcg
    50401 gtaacatttt atcatcagct aaagctacac aacttcttgg atttacaaaa gcaccacaca
    50461 tacaaattcc accaacagaa accaatgttc caaaggtaac caatccagct cccatatttc
    50521 caaagcatat tcttgcagca tctgccactg gtgtagatgt actagataac gaatctccta
    50581 gtataccaac acatacaact tgatttaata tatatattat tgatgcaatt actattacac
    50641 ttataattgc tattggtata tttttttgtg gattttccat atcttctgct gcaactgcta
    50701 tagattcaaa tcctgtaaat gaataaaaca ttaaaagtgc tgctgctcca aactctgttg
    50761 ctccagctcc tggaggtacc attgttgaag aagtaaaatt aactcctttt ataaaaaata
    50821 tacctattcc tataaatagt attaatggaa ttagtttacc tacagttata acattttgta
    50881 caatttttga tagagataca cctaataagt ttataattgt aagcccaact atcatagcta
    50941 caattataat tttttgtata tgtggttcac ctgctggagc ccatactgct gataatgatg
    51001 taggaaaacc tactattaaa gctccccaag aaatacatcc tattacccat ttcataagac
    51061 ctacttcaaa accacaaaaa tctccaaaag cttcttttgt atatacatag gcagcaccat
    51121 ttttattgaa tttacctgca acctcagcaa aacagaatgc catagataaa actaacaaca
    51181 tatcaaatat atatacaaat atacttgcta caccaaatga tttcattgca tctcctggta
    51241 atagaaaaac tccagctcct actactgcat taatacctaa aagtataata cttattaatc
    51301 ccattttgtt cttttcgttc atgttcaatc cccccaaggt atattataaa ttcgaacaaa
    51361 tatttataaa atatttaaat agtttttcca ttttatcaca gtaatctacc atcatttctg
    51421 gatgccactg tactcctact acaaaatttt catcctcttt ctcaatagct tctattatac
    51481 catcttttga gtatgctatg gcttttaatc cttttccaag ctgattgaca ctttgatgat
    51541 gataactatt tgtaagtaat tgttttccta aaattccctc taaaatactt ccttctttaa
    51601 catcaacttt atgagtagct acatgtcttt tagaagattg tgtatgtttt atataacttc
    51661 cttctataag attattatct tgatataaag ttcctcctaa acttacattt aaaatttgta
    51721 gtcccctaca tacacctaat ataggctttt taagttctaa tgctatactt attgcaatta
    51781 aatcaaattc atccacttct ggatatataa atgtcgtttc ttctcttgtt tcttctccat
    51841 acagttgagg attgatatcc catcccccag atattaagac tccatcaacc atttcaatct
    51901 gtttttttat aacttcttta tctgtattta caggaattat tactggacta ccgccacctt
    51961 ttagcactgc atttatataa tcattattta catatgacct ttcaagacct ggaaacatac
    52021 cattttccat tattattaaa tttcctaaaa tccctattat tggtttcata attaaactcc
    52081 taactaatcg attgttttat gtattacttt atattcatat aattttccaa tgctagagac
    52141 agttggtctg ggcaagatgt tggctttgtt ttacactcta ttccttttaa cttttgtatt
    52201 acatcttcta tattcatgcc ttcaactaat acttttagcc cttttaaatt tccatcacat
    52261 ccacctataa agtttacatt tgtaacttta ttttctttta cttcaaattc aatttctgta
    52321 gcacaagtcc ctgttgtttt gtatttcatc attaaacctc ccaattattt tgtcgtctta
    52381 tctctataat tagcaatatg tatgccaaaa tctataatta tttttattta ttatttatct
    52441 agtattttca atagttttat tagttgtatt ttttacttct aattctatgt acacttttct
    52501 tacaaataaa aataggtaat gggttattct aacttaacct attacctatc taatcctatt
    52561 ttaaaaacct attaatattt aattataaat tacaatattc tttctgacat aatataaatt
    52621 aatctctata aatataaaag tttattatta tttaaatatc taaattcaaa atatgtgatt
    52681 tcaatatcaa atacttagct taatttatat tattataaag ttttatcccc tctgaggtta
    52741 tttgacttcc tcctctacca gatttagatg atatgtatcc acattcactt aaataagata
    52801 gcacctttct aactttgctt tcagaaatct caataccttc ctgtataagc ttttcgatta
    52861 taaaccctct tccaattcca gaggatgact ctcttctttc atatagaatc ctcagtattt
    52921 cctcaaattc ttttcttgta taaccaaatc catcttcata attgttagca cattctaccc
    52981 ttatatatgg tggtaagtca tctctaaaaa ccatactatc acacattaga cttacataag
    53041 aagcaacatt ttgtaactct cttatatttc ctggccaatt atatttttct aaaatagtta
    53101 taacttctgg cgaaagtctt atattgtttt tcaaaaagaa attcataagt gttattatat
    53161 cttcttttct attcctcaat gatggtacat ctattggcaa tacatttagt ctataataca
    53221 ggtcctctct aaattttcct tctctaatca tctttagtaa gtttttgttt gttgctgcta
    53281 tgaccctaac atctatgttt ataacattat gggaacctat aggcataacc tgcttttctt
    53341 gtaataccct tagtaacttt gtctgtagca atggaggcat atctccaatt tcatccagaa
    53401 atatagttcc attattagca agttcaaata gacccttttt tccttctctt aaagctcctg
    53461 taaaagagcc tttttcatat ccaaacagtt gactttctaa tagactatct ggaactgctg
    53521 cacaattaac tgctataaac ggttgattac ttctattgga agcattatga attgattgtg
    53581 ataataattc tttaccagta ccactttctc ctattattaa tacagaaagg tctgatttag
    53641 atattttttt agccaattct acacacttta ccatattttt atttttagtt tttatatctt
    53701 taaatgtata tcttgctatc tgaccttgtt ctcttaattt attagtaaga ttttgttcta
    53761 atttttttat atacgttatt tcttgtaagt tataatatat cccagcttta ttccccatag
    53821 aaaaaatact ttttttattt acatttatat attttttatt tgtaaatacc acttcatcaa
    53881 ttatttcttt gtcttcaagt aaaatattta aatcttcaga aatgatatct tctatgtttt
    53941 tgccttgtgg attttcattt atacctaaaa tttttaaagc ttctttatta aatgtgttta
    54001 ttataccatc tgctgaagta aatattattc catcttttga tagattcaat ataacatctt
    54061 gttcttctat ttttaaaaac agttgcctat aattatcttt aactccatta tctaaactta
    54121 ttaaactctc agaatatgcc attaaatttt tacgtatttc tttaacatct attctaagac
    54181 catttattat ttctataaag gtagatatat caatatatct atttccaagg tcgattactt
    54241 tatttatata acttggtact tttcccttta ctccaggtgt tatagctatg tctatatttt
    54301 tataaatttt tccttcaata tatggagtaa actttaaatt ttttactcct attttgtaaa
    54361 ataagcttat cgtttctaag gtagtttctt ttgtatcatt tacaaccaat acttcagttc
    54421 catttggtat tgaaaataat ccatatattt cattttcttt aagtgttctc cttatcacta
    54481 taatcttact atcttgtact aaatgctttc tcatactgtt taatctatca tcattcatta
    54541 ctagtacaaa atcaccttgt attttatcat tctcttttaa aacttccaga taatagtggt
    54601 ttatatcaat ataattacct aaaaccaaac gtatattttc ttctaagaaa gatgatagtt
    54661 tagttatttt atcagttact atagctattg attgtttcat atttatacct cttatttata
    54721 tagtatataa ttacttatat actactttat ttctaccaag ttgttttgct ttatataaat
    54781 ttttatcagc ttcttctagt acatctttgc tatctgaaac atgagctaca cctgcactta
    54841 tagtcacagt cacatcatca ttccactttt tatttgcaat tgcaaccctt atactgtcaa
    54901 ttatatctgc tacttcatca ccagatttat ttcttattaa tacagaaaat tcttctcctc
    54961 cgtacctaaa gactttatca tcttgttcta acataacaca aatggtattt gttattccct
    55021 ttataacagt gtcaccaaat ttatgtccat aattatcatt tatgagcttg aaattatcaa
    55081 tatctatcat cacaagtgca aaattatcat ctttctctct gtacttttca tacataatat
    55141 caaaactttt tctattataa acatttgtaa gaccatcatg taaattttgt gctttaaaat
    55201 acttcaatcg gttgtataaa aaagtagacc ctaatatagc aattaaaatt actgtaaata
    55261 atattttata atattttatt tcttttttag ttttttcaaa tagcttactt tcgtttgata
    55321 ctttatcaat tatatagaaa ctagtctctg aatctcttat acttttgttc tctttatatt
    55381 catttattaa catcttttga tactcattta aagattctat atttccttgt ttttcatata
    55441 tatttaatat cttatttaaa ttttttattt tctcctgggt taactttctt ttagtagata
    55501 tctctaaact ttttttataa ttatctattg cagaattata attttcgctt ttatattcta
    55561 agtttcccat tgccatataa tagtacatat ctttatctaa tatataaact gttctatctg
    55621 attttataag ataatcagct ttttctaaaa aagtctttgc cttttgtata ttatttttgc
    55681 ccacatacgc atttgactgc attatagagg ccattatatc aaaatcattg taattatccg
    55741 tatttacaaa ctttttataa tcttttatcc tgctacttat ttcaatagct ttatcatatt
    55801 cgccctcttc tacatatatt tctgctagat ttataatagc atataatcta accattccat
    55861 ttttttcacc ttcatcaata tctattttaa aagaatcctt tattaatttc tctcctgttt
    55921 catagccacc tatctttaaa aatatgctcg ccaaatcaac atctagtctt gctttttcat
    55981 aattattccc caatttctca gccaacttta tagactttac agttaaatct actgccttag
    56041 aataattatt atccattata tacactgatg ctaatctttt ttctatatta aatctacatt
    56101 catcagataa tttcacatct gattctctca tcttttctaa agaatcaatg actatcttcg
    56161 ttccatctgg aacatatgaa atagtcttta acatatccca aacttcatta tatactttat
    56221 tgtatttttt ttctggaata gattcaaaag aagtcttaac cacttttttt gcttcatcat
    56281 actccttatc tgccacaagg ctttcagaca tatattttcc cttatttata atttctcttt
    56341 ctttcaatcc attttggtca tactttataa acaaaataat actaataagt attatacata
    56401 taaaaattat ctttttgggt aaccttttct ttggtagtct aaaattcaaa attttagtcc
    56461 tccttttgta tattgtagaa tgaaaacttg catatataaa taacctctta ataattaata
    56521 atacaatata tcaaaatgat ttacaacata tcctagactt aaatcttaat aaaaaaatct
    56581 cctaaaataa tttaggagac tttaaattta agctaatata aatttataca gttaaaacaa
    56641 gtgcttgttt tttagtttta tatttaatat ttatttatac atattttttt agtactattg
    56701 tagcattatg cccaccaaat cctaaagaat ttgatagtgc atatctaata tttttttctt
    56761 taccttgatt tggaacataa tctaaatcca aatcttcacc aacttcttgt atgtttatag
    56821 ttggaggcac aaaactatct tctatactca tagcacaaac aacagcctct atagcacctg
    56881 atgctcctaa taagtgacca gtcatagatt ttgttgatga cacacataag tcatatgcct
    56941 tttctccaaa tacagttttt atagccatag tttcatataa atcattgtaa taagttgaag
    57001 ttccatgagc atttatataa tctacttctt ctaatggaac atttccatct ttcaaagcca
    57061 tattcataga cctagctgct ccctctccat tttcagctgg agttgtcata tggtatgcat
    57121 cagcagttaa accatatcca actacttctg catatatttt agcacctctt gctaaagcat
    57181 gttctaagtc ttctaagata acaatacctg ctccttctcc cattacaaaa ccatctctgt
    57241 ctttatcaaa tggtcttgat gcagttttag ggtcatcatt tctagttgac atagccttca
    57301 tgttacagaa tccagcaaaa gcaagacctg ttacagcagc ttcagaaccc cctgctacca
    57361 taaggtctgc atcacctctt tgaattacct taaaagcatc acctattgaa tgagttcctg
    57421 atgcacaagc tgtacataca ttagtgttag gtccttttgc tcctaaaaat attgaaactt
    57481 gaccagctgc catatttcct atcatcatag gtacaaaaag tgaacttact cttttatttc
    57541 ctttttccaa aagaatttta tgttgagttt ctatagcttc aactccacct attccagaac
    57601 ctattataac accaaaacgt tctctatcaa ctttatctaa atcaagattt gcatcttcaa
    57661 ctgctaattt agcagatact attgcaaatt gagcaaattt atctaatctc ttcaattcct
    57721 ttttacttat atattcttct ggatgaaaat tcttaacttc tcctgctatc tgagtttgat
    57781 atgtgctagc atcaaaatta gttattttat ctataccaga tactccagat tttatattac
    57841 tccagaactc ttcttttcct gttcccaacg gcgtaacaca tccaagtcct gttattacta
    57901 ctcttttatt catcggatac ctccactttt ttaaagctcg actatttatt agcttctata
    57961 tacttaacta tatctcctat agatttgaag ttttctgctt ctgtatctgg tatttctata
    58021 ccaaattcat cttcaagtgc cattattatt tctactgcat ctaatgaatc tgcttctaaa
    58081 tccttcatta atgatgtttc catagttatt tctttatctt ctactcctaa ttgctctatt
    58141 attatttcta caactttatt aaacattgtg tacctcctaa aattttttat tttaatagat
    58201 ttctctactt tttaaattat tattgcatta ccattccacc atctacattt attacttgtc
    58261 ctgttatata acttgacatg tcactaacta aaaatgctac ggcattggct acatcttctg
    58321 gtttaccata agatttcttt ggtatgtttg ctagtgttga ttcttttaca tcatcactta
    58381 gtactttagt catatctgtt tctataaatc caggtgctac tgcatttata tttatgtttc
    58441 ttgatgctaa ctctcttgca gaagcttttg taaatccaat tacacctgct tttgatgcac
    58501 aataattagt ttgccctgca ttacccataa ttccaactac tgaagtcata tttattattc
    58561 ttccatactt ctttttcatc ataggtttag taactgcttt tgtacaatta aagacacctt
    58621 ttaagtttat atctataact ctatcaaaat cttcttcttt cattctcata agcagaccat
    58681 ctttagttat gcctgcatta ttaaccaata tatcaatttt tccaaattcg cttacaacag
    58741 aatctatcat ttgattcact tcatcaaatt tagacacatc acattttata gaggtacact
    58801 ttacccccat actttctatt tcatttttag tttttagtgc ttcatcttct ttagaagtat
    58861 aattgattac tacatcagct ccaaaagatg ctagtttttt tgctatttct tttcctatac
    58921 ccctagaacc accagtaaca actgctactt gtcctgtaag atttatcatt atatctctcc
    58981 atttctataa ttttgtacaa attcattaag agaatctata ccatctatat tataaatatt
    59041 gacatttgct tttttattgg aagctatttt cttaataaat gcttttaaag tttttccagg
    59101 tcccatttct ataaaagtat catatccatc atttaaaagt ctttctatag aatcttccca
    59161 aagaacagat gaacttactt gttttataag caggtcttta ccttcgtttt tatagtaatc
    59221 tgcatttaca tttgccacca catcaacttt aggtttagtt atgttaactt tttctaattc
    59281 actggccaat tttacaccag cttcttttaa cattgatgag tgaaaaggtc cacttacatt
    59341 taatttaact gccctttttg ctcctgcttc tttgcatttt accattgctt cttctatctt
    59401 ttcattttca ccagatataa ctatttgtcc aggagaattg taatttgcta cttctacaat
    59461 acctccttgt atatctttaa ccacattttc aagtacattt ctatctaaac ctaaaactgc
    59521 tgccatagct ccaacacctg ctggaactgt ttcctgcata aacttacctc tttttttaac
    59581 taaacataca gcatctttaa agtcaattgc atctgctgca accaacgcac tatactctcc
    59641 taaggataat cctaagcatg cattatattt taaatctatt tgagcttgta ccgcttttaa
    59701 tactgctaca ctatgtgtaa ccatagcagg ttgagtgttt tcagttttag aaagttcttc
    59761 ttcatttcca ttaaacataa ggttttttaa atccatattt aaggcatcac tagcctcatc
    59821 tattacactt ttagcaacag cattattttc atataaatcc ttggccatac ctacatattg
    59881 agctccttga ccagggaata ctagtgcaac ttttcccatc ttgctcctcc tgatttacag
    59941 ttctattgct ggcataatct ctcttgcttg atttaccata gcctctataa tttccttaca
    60001 aggtgttatt tcttttacca tagcagcact ttgacctgcc ataaatgaac ctttttctat
    60061 gtctccatct actgttgcaa atcttaaagc tcctgtacct tttttatcca gttcttcagg
    60121 agtagctcca ttttgttcca tctttaaaaa ttcttttgat agtttatttt ttaatgttct
    60181 tactggatga ccagtacttc ttcctgttac aattgcatct ctatcttttg cttttagtac
    60241 taagttttta tagtttgaat ggacagaaca ctcttcactg caaataaatc tagttcctac
    60301 ttgaactgca ctggcaccta atgcaaatga tgctgcaatt cctctaccat ctacaattcc
    60361 tccagcagct attacaggta tgtttacagc atcagcaact tgtggaacta agaccatagt
    60421 agtaagttct cctatatgtc ctccaccttc agtaccttct gctattactg ctgtagctcc
    60481 tagcttttcc attctttgtg ccaaagctat tgtaggtact acaggaataa cctttgttcc
    60541 agcttccttt aatctatcca tatactttgc aggatttcca gcaccagtag taataacttg
    60601 aactttttct tctataatca aatcaattat atcatcaaca aatggcgaca taagcattac
    60661 atttactcca aaaggcttat ctgttaattt tttacactca acaatttctt tctttatagc
    60721 ttcttttggt gcatttcctg ctgctattat gccaagtcct cctgcattag atacagcact
    60781 tgctaatgat gcagtagcta cccatgccat tcccccttgg ataactgggt attttatatt
    60841 taatattttg caaattttat tcatacaatt ctccttcact tgaaatcata aaagtaaact
    60901 ttttattatt aatcaacttt attttgtgta taagtttaat tttgttaatt aaatcatttt
    60961 agatatttta tactataaag tccacttgac aactgaagcc ccccaagtta gacctccacc
    61021 aaagccaact aaaactacat tatcaccctt tttaatttta ccttctctat aagcttcatc
    61081 taatgctact ggtatagatg cagcagacat atttccatat ttgtctatat ttacataaac
    61141 ttttttcata tcaagctcta atctcttaga agaagcttgt atgattctta tattagcttg
    61201 atgtggcact aagtagtcta tatcagttgt atttagattt gctttttcaa gagctcttaa
    61261 agaagtttct gccatctttc taactgcaaa tttaaacaca tcactacctg ccatttctat
    61321 tgtatgtaga ttagcttcta cagtctcttt acttgcctta agtcttgaac ctccagcagg
    61381 tacttttaaa caatcttttc ctttaccatc agagcccata tgtgtagaca gtattccacc
    61441 ctcatttaca gggccaataa cagctgctcc agctccatct ccaaacaata ctgctgttgt
    61501 tctatcatca taatttaaaa acttagaaca agtttctgct cctattacaa gcacattttt
    61561 atagcaacct gtttccacaa attgctttgc aatagttact ccatatacaa atccagaaca
    61621 agctgctgat atatcaaatg cagtagcatt tactgctcct attgcatctt gtactataca
    61681 tgcagttgaa ggcaaagaca tatcaggagt aattgtagct aatataatca gctctatatc
    61741 ctctacgttt aactttgcac attctatagc ttttaaggca gctttagatg ctaagtcaga
    61801 agttgcttca gactctttgg caaatcttct ttccttaata ccagttctag tacttatcca
    61861 ctcatctgat gtatccatta ttttttcgaa gtgaaaatta tcatatgatt gctcaggtag
    61921 ataacttcct actcctaata ttccagcctt tgtattcatt atatattaaa cctccaaaac
    61981 gagtttattc atcttcgtta tttttatttt cttcattgta tttgcttata aattggttaa
    62041 tatcttcaac gacttttccc tttgaaaatt ttattccttg atttatagca ttttttatag
    62101 ctttagcatc agaactacca tgagctttta taactcctcc atttagacct aaaagtggag
    62161 ctcccccata ctcagaataa tctataaaac tttttaattt tcttaaatca tcctttataa
    62221 gtaatgctcc tattttactt tttgtactgg ccataaaagt ttcctttata agactcataa
    62281 ctgaaagtgc tacaccttca gcagatttaa gtaatatatt acctgtaaat ccatcacata
    62341 tgattatatc tgtgtatgca tttataactt ctctagcttc tacattccct ataaaattta
    62401 aatctaattt tttaatttct tcatatgacc ttttgactaa atcattgcct ttgccttctt
    62461 ctagtccaac atttgctaat gctaccttag gattttcaag acctaaaact tttcttgaat
    62521 aaatattact catagctgca aattcaacta gattcttagg tttacaatct gcatttgcgc
    62581 cacagtctgc tataagtgtc attcctcgct ttacatttgg tattgctgaa cataagcaag
    62641 gtctatcgat tccttttatt ctaccaacaa caaataatcc accagcaagt aaggctcctg
    62701 tatttccagc tgatattata gcatctgcct ttccttcttt tacaagattt aatgctacta
    62761 ccatagatga atctttttta cttcttatag cctttactgg tttatcttcg ttttctataa
    62821 tctcagtagt atgaactatc tctaatttat ttctatcaaa ttcataattt gaaaattcct
    62881 tttcaagtaa atctttatct cctgtgatta ttaaatcaac ctgatattct tttatagcat
    62941 ttactgcgcc ttctacatta gatttaggtg cattatctcc acccattcca tcaattacta
    63001 ttttcataat ttccctccta atctaattct tcaaagataa actttcctct aaatatttgc
    63061 tcttgggctt tattgttgat aacaactttt acataatgct ttttatctat atttctatac
    63121 acttctgctt ttgctataag cctatcttgt tgttctatca acttaaaact ttttacattt
    63181 gcaactctca taataacctt aggtgcatct attatagcca ttgccaatga atctgctaga
    63241 gaaaaaatat acgtatcttt taaagtatta gtcttagagt aaatcatgtc ctgtgtaact
    63301 tctaacatag atatacctaa tcgccctaca gataaatcaa tgatttctcc tgtaatttcc
    63361 tttactccta aagtctttac ttttgaactc tgagtttctg ctattgattt gactctttct
    63421 cttagctctg gtatgtttag actcattcta tctaatctta tggtctgtat acttacatca
    63481 aacagacttg ataattcttc atcagtataa aaaggatctg tctttagcat atctataagc
    63541 tctttttgtc tttgggcttt acttttcttt ttcatgttcc ctccaaattt tatagctgta
    63601 attagtacca gctactaata gtagtatata gtaacacaca aaaattttca atacttatat
    63661 tattattttt ctatttttta atatgcataa aatccactta ttttctctag taaattatct
    63721 tattttttta tatgtacaaa aaaaacatgt agagtatact ctacatgctt tttagaagct
    63781 attacttaga cacaacttct ttacctttat aatatccaca gtctggacac actctatgtg
    63841 gtaattttgg ctcatgacat tgtgggcaac ttacaaatcc tgttgcttcc atctttgagt
    63901 tagctgctct tctcattttt gtgtttgatt tagacgtttt acgctttggt actgccattt
    63961 acgccacctc cttagtcaaa atttaattaa ataaatcttt taatttagca aaacgaggat
    64021 ctatgtattc ctcatcgttt gtaatttcac tgcaagaaca ctcttcttca tttaagtttg
    64081 ccccgcatac ttgacaaaga cctttacagt tttcactaca aagaacttta tgaggtacat
    64141 taaaatctaa tgtctgttct attatatcaa taaggtcgat ttcttcacca tcgaatataa
    64201 aaggatcaaa ttcctcaaac tcatcttcat cataatcttc ttcttttact aaaaaacctt
    64261 gtatagaata ctctagtggt atttctactt ctttaagaca tcttgaacaa ttgtcaacaa
    64321 ttgtaaaatt gacatctata tctagataca aacctttatt agtctttgac actttccctt
    64381 ttaaatttac aggtgatact aatttgtaaa tctcatcaca ataactaata gtatcaattt
    64441 tttcacaaaa attcaagtct attttgtcag tttcttttct atttattttt tctatgctaa
    64501 ctttcattaa gttcacctca acatatcacc aaatttatta tacaaatcta gcatttgttt
    64561 gtcaagtatt tttacttgat aggcataggt ttaatttaat tattttacca atcttaatgt
    64621 atctctagct atcattaatt cttcattagt tggtattaaa agcattttta ctttagaatc
    64681 agcagtagat attactgttt cttttcctct aacatcatta gcttctttat ctaatttcat
    64741 tcctaaaaac tccatgttag aagcaatatc tgctcttata gcctttccat tttcaccaac
    64801 gcctgcagta aatactacaa catccaatcc attcatttca gcagcataag cgcctatata
    64861 tttttgtact tttttaacat acgcttctaa tgtagcttga gctctttcgt ctccattttt
    64921 agctgcatct tctatatctc tgaagtcact agaaattcca gtcattccat atactccaga
    64981 ttctttattc attaatttat ccaatccatc agcatctaaa ccttcttttc tcattaagaa
    65041 tggtaatata gctgggtcta tatctccaca tctagttccc attattaatc cttctaatgg
    65101 agtgaatccc atagatgtat ctacacattt tccaccatca acagcagcta tagaagcacc
    65161 atttcctaag tgacaagtta ctatttttaa atcttttata tcttttccta atatctctgc
    65221 tgctctttga gatacataat tatgagaagt tccgtggaat ccatatcttc ttaccccata
    65281 tttagtatat agctcatgag gtaaaccata taagtatgaa gatttaggca ttgtttgatg
    65341 gaaagcagta tcaaatacac ctaccattgg tacatctgga agtatagctt tacaagcatc
    65401 tattcccatt atgtttgctg gattatgaag tggagctaaa tctatacatt cttttaaagc
    65461 ttcttctact tctggagtta ttactactga agttgcaaat ttttctccag catgtacaac
    65521 cctatgtcct actgcatcta tttctttcat ttctttaact gcaccaaatt ctggatgagc
    65581 aacagcttct aaaactaatg ctattgcatc tttgtggtcc ttcattggtt gttcaacaac
    65641 gtatttatca tctctacctg ctttttcatg ttttaatata gaaccttcta ttcctattct
    65701 ttcaaccaat cctatacata aaacttcttc attattcata tctattaatt gatattttaa
    65761 tgaagaactc ccacagttta atactaatat tttcattatt atttcctcct tagatttttt
    65821 tataaataat atgtaataaa ttttgatttg taataaatgt ctaaataaaa ctctatcttt
    65881 tattattttg ttatagatat attattgtat acattaaacg attttcataa ataatatatc
    65941 accttttaat ataaaagtat atactttttt tttatattat atcatatttc tagtatggta
    66001 aattgtgtat ttcactaata atatattaac aagttaactt aatgtagatt attctttccc
    66061 atttgttata ataatataat ataaagagct aataaagtta ttttaataac atttaaccag
    66121 ttttttatgt aggtaacatt tctacatttt tataaatttt tttacgtttt ttaattttat
    66181 aattaaaaat ttaaatttta tacatattat aataaattgt gatatatata aaataattaa
    66241 agataaaagg agtattttat gaacatactt ggattaatag ttgaatataa cccatttcat
    66301 aatggacaca tatatcattt atctaaatct atagaaaaaa caaatgcaac acatactgta
    66361 gcaataatga gtggaaattt tctacaaaga ggcgaaccag ctttatttga taaatacact
    66421 agagcaaaaa ttgctgtcga aaatggtgta gacttagtta tagaattacc aactttattt
    66481 gcttgtcaaa gtgctgaaat tttttctcat ggtgctataa caattttaaa ttcactaaac
    66541 tgcataaatt ctatatgttt tggtagtgaa gaaggaaata cagaaattct ttataatcta
    66601 gctgaaattt tagcaaatga accaaatgaa tttaagttac ttttaaaaaa atatttagat
    66661 gatggtctgt tatttccaac agctagagct aatgcacttt ttgattatat acatcaagac
    66721 aaaaaaaata attttataca aaattattca aaggaacaat tatcaaaaac attaaattca
    66781 tcaaacaaca tactgggtat agaatacata aaaaacctca tccatttaaa cagtagtata
    66841 aaaccattta ctatctccag ggtccaatca gaatataatt ccgaagaaat tgagagtgat
    66901 atttgttctg ctactgctat aagaacttca cttaaagaaa atacagacct ttttcattta
    66961 aaaaatgtta ttccagaaaa aacttataac atcctaaatg aaaaaataga taatggtttt
    67021 ttacctatgt ttgatgactt cttctttgat attttaaaaa caattatact tagagatatg
    67081 gacactttaa aagagtattt tgaagtaaat gaaggcatag aaaacagaat ctataaagat
    67141 atctttacat ctgaatttct acatgaacta caattagcaa ttaaatccaa gcgatacact
    67201 ttaaccaaaa tcaaacgaac tctaaacaat atattgttag gtattaaaaa aagcgacgtg
    67261 caacttataa aaaacataga tactatacct tatataagaa tacttgcttt taatgataaa
    67321 ggtagagaaa ttctaaaaga gataaaaaat aaatctgaaa taaaaataat aaacaagttt
    67381 tcaaatatat cattttcatt agatgatacg atttttaaaa cactcataag ttatgatata
    67441 aaagctacaa atatatataa ttcaatatat tataaaaaca ataaagattt agtaaaaggc
    67501 cctatggatt tttatactca tccaatatat gtaaagtagt tttttaaaat aactatattt
    67561 ataaaaatca ttttattaac tctttattat ataagataca atagtcttac tttatttatg
    67621 tacacatgct tttaggatga caacatcaac ttaaatatta tgttactttc taaatttaag
    67681 taaatattgc catcctaaaa attttacaat ttagcttcag atttaaaagt aaagtttaaa
    67741 atattatatt taaatctaat ttaatatttt ttgttttata aatattatta aattaatatt
    67801 tctaatatat tttccctgga tttaaaatat ttttagggtc aaaagctaac tttatatttt
    67861 taattaacat catataagca tctgaatttg attcatgtaa gtactctttt ttagcatatc
    67921 ctatgccatg ttcaccagaa acttgaccac taagttctct agatttttta tacatatagt
    67981 caaaagtttc ttttaatctt attttccatg tattatcatc cataccatct tttaaaatat
    68041 atatgtgtag atttccatct cctgcatgac caaaactttt tattcttatt tttaatttgt
    68101 cttgaagctc gtgagtgtat cttataaact ctgctatctt atctcttgga acaacgacat
    68161 cacattcatc catttgtgtc gtagatgcct ttatagcttc taaaaatgca cctctggctg
    68221 accatataga atcgtttctt tcttgtgtat ctgatataaa tacatctaat gcaccatttt
    68281 ctaaacataa attagctact ttttcatatt ctttttctat atcttcagtg ctatttccat
    68341 caaatgtaag caaaagataa gcatctgatg tattatctgg aaacttttta cctaaaaatt
    68401 cttctgctgc caatatcaca tctctttcca taaattctat agccgttggt attgattttg
    68461 attttattat tttaggaaca gtttctattg ccattgataa atctggaaat ggtataagca
    68521 aacttatact tttctttggt aaaggaagca attttaatat agctttagta actattccta
    68581 aagtaccttc tgagcccact aataaatcct ttatactata tccagaacta tttttaacca
    68641 cctttccacc tacatttata atttctccat ttggtagtac aacttcaagt cctcttacat
    68701 aatcccttgt aacgccatat tttactgctc tcataccacc tgcattagtg tttatattac
    68761 ctgcaattgt agcacttttt tcacctgggt caggtgggta aaataaatct ctatcttgaa
    68821 catattgacc tattgtcatc aataaaacac ctggttctac tgtcaatgtt aaattttcat
    68881 aatcaacttc aagtatttta ttcattttac atagattaat cattattcca ccatttatgg
    68941 caacagcagc acctacaaga ccagtacctt gacctcttgg tgtgactggt atattatttt
    69001 tatatgcgta tttcattatt ttagatactt gttcagtttc aagtacattt actaaaactt
    69061 cagggtactt ctcaatccct ccaagttcat catgtgaaaa atcttcattt atatcacttc
    69121 caactaatac attttcttct ccacaagtat ctattaaaaa atctatatct tttttatcga
    69181 ttaatttata catttctatc cccctattta gctgctgatg ccatatattt ttgattatta
    69241 tctttgttat tttctatttt ttcaatcaat ttaggaataa tatcataaat atcacctatt
    69301 aaagctaaat gtgctacatc aagtataggc gctttatcat ctttatttat tgctactata
    69361 tagtcagcac cctgcatccc tgcaacaaat tgaactgctc cagatacacc acaagttatt
    69421 atcaatttag gttttacagt tctaccacta agacctattt gttttttagc atctatccaa
    69481 cctgcttcta ttacaggtct tgttcctgcc acttgagcgt ttaacttatc agctaattta
    69541 tatatcatct ccatatcttc ttgttttttt attgctctac ttgccacaac tatcacttca
    69601 gcttcttcca gaccaacttc tttatttttt tcttttacac tcagtacctt aattttagat
    69661 tttagttctt ttttttctac tttacataaa gttatctttc ctgtagtatt ctctattttt
    69721 tctggtgctg aaaatatttt atatcttaca gtggcaaatt gtggtctatt attaggtgtg
    69781 tttatatgag ccattatatt tccaccaaat gctggtctta tttggtctaa atcagtattt
    69841 gattgaatat caagtattgt acaatctgct gtaagacctg ttctaaatct agcggcaagt
    69901 cttggagcta atgacctacc taatgtagtt ccaccaacta atactatcgt tggttttatt
    69961 ttatctataa agttttctat tgcttttgaa tatggttcta tcctaaaatc tttaaattca
    70021 tcttcatcat atacaaatac ttcatccacc ccataagaaa tcaaattact gcacttatct
    70081 tttatgtctt ttcctacaaa tacacaatac acaggttgtt ttatttttga tgccatctca
    70141 cgagctttac ctataagctc gtacgttaca ggatgtatat ttccattatg atgttcaaca
    70201 tatactgcaa ttcccctcca ttcatcttta ttaatttgta ctttactact ctctataaat
    70261 tcaaatgcgc cttttggtcc acttttgaca cacaacttgc acatcttaca gccagcactt
    70321 atttctacta tacctgactt ttcttctata gccccaaaag gacatatttc taaaattctc
    70381 tttaagtcag ttattttatc ttgatttaca actatctttg acatttatta ctccccctta
    70441 caccaacttt aattcctcta atttatttac aagtgcaaaa cttagttcat ctgcatttcc
    70501 tcttacaata tttttatctg tatttggctt tggaggaaat attcttacaa cttgagtagg
    70561 agaaccatta agtccatagt tattttcatc tttatcttca aagtcatcta agctatatac
    70621 aggtatttct ctatctttag tattaagttt taatttaaat gaaggtagtc ttggttgaaa
    70681 aatgtctttt tctacagtta ttaaacatgg atattcaatc tcacatactt gtaaatcatt
    70741 tggcatatct atttcaacaa ctatactttc atctttaact tcaattaatt ttgtaacgtt
    70801 agtaacatga ggtatatcta aaaattcagc tacttcaggt cccacctgtg ctgtatcacc
    70861 atcagtagtt tgttttccac aaattattag gtctaccttt cccatcttct taataccttg
    70921 tgatatggta taggaagtag ccaatacatc tgctcctcca aatctcctat cacttattaa
    70981 tgctccttca tcagctccca tcataaaact ttcttcaatt accttctttg cctgaggagg
    71041 acccatgcta agtactttta gattcgcttt cttatcttcc tttattctaa gagctgtttc
    71101 taaagcatat aggtcatagg gattcatttt tgaatctact ccatctcttt ttagtactcc
    71161 tgtagtttca tcaacttcta ctgaagtcgt tccaggaact tgtttaatac atgtcaaaat
    71221 ttccataaag tacactcctt ttttatttaa ctataactga tactccatca ggtataacta
    71281 ctactttgct ctccttacca actatactat tcgccatttc taaagcttct ttaaagttaa
    71341 atgcatgttt catatgcatt ttttttatca tttcaggatt acacttatct gttaccatta
    71401 tcacagtata tttagataat attctcgcta gtatctgaaa ttcccattgg tctggaatcg
    71461 tatctactct atcgacactt ctaattttat ctaaaagttg ttttggagaa tctgcatttg
    71521 ctacattttc ataaaaagat tgacctccat gaccatcatt acatgctgaa atcattatta
    71581 ttactccacc gtctttacaa gtagcttcag ctgctgtcat tcctttaaca gattgataaa
    71641 tattttggtc tagtggatat ccaccatttg tagttacaac aatatcagat tttatagaat
    71701 ttacttttga taactctgtt acaaatctac atcctttagt atgtgctttt tcgacatcac
    71761 cagcaaagga agcaattatt tttttatctt tatctattac aacattcaat atgaatgcta
    71821 attttgcaac tttagctgca tataccatat cctcatgaat aggattatta ttcaattttc
    71881 cagttcttga attatcacta tctataaagt cactacaatg attgtacatt atagtctttg
    71941 cagatgcgat tcctggaagt acactttttc tgccacctga aaaacctgca aagaaatgag
    72001 gttctataaa accttctgct atcaaaagtt ctgcctcata tgctagtttg tttatatata
    72061 aatctccacc tgaaggcaat atccctactt tacacataga tttatcatca gtagatatat
    72121 gcataactat atcttcatta tctactattt cttctcccat tttataaatt agctcttccc
    72181 ttgtacttgg cctatgaaat ccagttgcca ctataatctt cacatcaatt tctggattaa
    72241 cattcctaat ccttcttaat ataattggca tagttattct acttggtaca ggtcttgtat
    72301 ggtcacttgt aattatgact acattctttt tccccttaac cagttcttcc agagaattag
    72361 agcctatagg attattcata gattcttcaa ctatctcttc ttgagtctta tgttctatat
    72421 aattatccga ttttgactcc aaaacaccga gaaaacgttc atcaggtatt tctaaaatca
    72481 ttccttgttt tgaatacggt acttttaact ttaccatttt taatctccca ttataataaa
    72541 ctataaaatt ggtatgtggt cataccagtt ttacatttat atgatagtac cattatctac
    72601 catttgcaag aataatttat tttataacaa acttttaatt ttcatttttt ctataatttt
    72661 tacttataaa atccatatgt tcctttgctt tctcacatgc aagttctaca tcattttcta
    72721 caactgcatt gtatatagct tcatgctgtt taagcaatat attttcatta aaaggttctg
    72781 cgattatttt ttctcttgca tcttctataa atccatcaaa taattttgat gctgtcataa
    72841 aaagactttg aattaaataa tttttactta atgttgctag tttactgtga aatttttggt
    72901 ctaataacac cagtactcga ttattatctt ttttattagt ttctaccctc atttcatcta
    72961 ttatatgttt caattctata acttcagaag aagttattct ctttgaagca agttttgcaa
    73021 tctcaatttc taggattatt ctaagctcta atatatcttc aagtgtacca ttattaagtt
    73081 taaaaatcat agataaaggt tctattaaag ttttttctat atttgtacat ataaaatttc
    73141 cttcaccctg tctgctttct atcactccca tagtctctaa taccctaata gcttccctta
    73201 tggaagttct actcacattc atttgttcag acagttctct ttctgatagt aatttatccc
    73261 ccttttttaa ctctccattt agtattttat attgtatttg ctcaattact tgttcataaa
    73321 cttttttact agctatacta ttaaacattt tttcctccaa tatgataatc gttgttgtaa
    73381 tatatatcta ttatatatct taagccatta cattcatata tttttattac ttttaatata
    73441 atatcttata actcaaattt acaggtgata ttatgaaaaa aaataaaatt attgcttttt
    73501 ttgctccatc tatcatagtt ggagttctag ttttagggat tatcctatac ccaaatgaag
    73561 ctataaaatc tgcaagagaa ggcttttcta tatggtctaa tgttttagtt ccatcactac
    73621 taccatttat aattggagca aacttaattg ttgatttaaa aatagtggat attatagggt
    73681 ttatcatcaa tcccataact agatttgtat ttaatgtttc aggaaagagc gctttagctt
    73741 ttgctatatc tacagtatct ggttatccag taggagtaag tttagcttct gaatttagga
    73801 gtaatggaca aatttctaag tatgaagcac aaagacttgt gtctttttgt tctacatcag
    73861 gacctttatt cataataggt tcggttggta caggtatgtt ccaaaattca aacttaggtt
    73921 atttaatgat tctctgccat tatctaggaa ctatattggt tggtcttttc tttagaaatt
    73981 atggtaatga aaatcttcca aagacaaaat tggatttaaa aacaaatata aaaaatgtaa
    74041 tcaacattag aaattcaagt gggaatggtt tttttgtttt atttggaaat gctgtattta
    74101 atggagtaaa tacattactt acagttggtg gatttgtaat tgttttttca gtagtattta
    74161 aaatactatc tctttttaat gtaatctcat taatagcatc agttatatat ttgcctcttt
    74221 catttttagg tgttagtaaa gaactctgtc aagcatttgt aagtggtcta tttgaaatta
    74281 ctataggatg caataaagta tctagtataa caagttctcc agaaatttta agagcatctt
    74341 tagctagttt tttgatagga tttagtggat tatccatcct agctcaatgt tgtacatttc
    74401 tatcaaaaac ggacatagat ttaaaattat acatactaag taaatttgcg catggagttt
    74461 tagctgctat ctttatattt atactttatc caattgcaaa ctctgctgtg ttggtttcta
    74521 gctttgctga tacatacaac gttatatata ataatttaat ctggttttat tatcttagct
    74581 attatgatac aattcttcaa attgtagtaa taatttatct aatctcagcc gtatttattg
    74641 caaaaaaaca tatgaaaact ttatctacaa atgggaaact aatgcgatat aaaaatactt
    74701 ttttcactaa gaaattttca cgaaaaaaat aaaactaaaa ataaaactaa taaaacttaa
    74761 ctaaatactt ccattttttt attatatttg tcataatttt aataaccttt ttaattagtt
    74821 taacagcata gttatttcat cacaatttaa taattttatt agaaatattt ttcaaaaaat
    74881 tctccttaat cacatatatc acacttgtat aagtttactg ggaaattttt ccattatata
    74941 atatttcatt tatattatat aataaatacc gacctaaact taccaaatca aactaagagg
    75001 agtggttgaa aatggcaaca agacctatag aaatagacga atataaaaag ataatggaac
    75061 tattacatac tggctttact tatagtgaaa atggcgttga aaaaagattt agaaaaaatc
    75121 ctaaagttgc attggcacta atgttagaag ctaatttagg tctaagaata tcagatattt
    75181 taagattaaa gataggtaat tttaaaggta atatgttgga aataaatgaa aaaaagacgg
    75241 gcaaattaca gtatagacca gttaataaaa atataattga gtccataaat gaacatgcaa
    75301 gaaagtataa tcttaaatca aatgactact tagtaaatat aaagacaaag gctattcaaa
    75361 aacagttgag gataatttgt aaatacttaa atctgtataa tataagtaca catagcttta
    75421 gaaagctcta tgctactact caatttgaaa agagtaacaa taatttagag ttggttaaag
    75481 aacttttaaa tcacagctct gtagccacta cacagcgata tataagggta actcagcaag
    75541 ctattaatga agctagtgaa aatttcttta ttggttaatt ataacgtata catttttcta
    75601 ttatcttatt aattcaccag atattaaaaa agagtgtctc aaaatgaact ttttagttca
    75661 tgagacactc tttttttata aaatcaaata tatttttatt atttcaacac tggaaaaaag
    75721 gcttatctct ctattttgag acaccctatt aaattttcat aattcttgca taaacatatt
    75781 aatctatctt caataatttt ttagctgatt cactgtaatt atttcttttt acaatttcca
    75841 aaactctatc aatctcatgt tctgactttg cacttacaaa aatcgccaat tcttcatcat
    75901 ctataatatc ataactatct acatatttat ctaaacattc taaaattcca tctttattat
    75961 tatacccacc aaatctaact actgcactac actcatcttc tataagtcca cttaaatcca
    76021 atttcccttt tgaaaaagac tttatatttg aacttctatt atctattata tctataatat
    76081 ctgcataaac agcacttcct gttgcacctc ttccagctcc cttacctaca aaagaaagtt
    76141 cacctactga atcacctact aaaataacta cgttgaactc attatctatc tttgaaagca
    76201 tattattatt gtccactaat gctggtctaa caaatccact tacttctcct gattcatact
    76261 tacttctagc aaccaatttt atcttacaat ttaatttttt tgcatattct atatcttttt
    76321 catctattga agttattcct tctaataata aatctttcca atatactatt tttccataag
    76381 ataaagtaga caatatagat aactttctag cactatcata tcctaaaaca tctgcatctg
    76441 gattaacttc tgcaaatccc aactcttgtg cctgttttaa agcgacatca tacggtaaat
    76501 tttcatcata catctttgat aatataaaat tacaagtccc atttaaaata gcgtttatgc
    76561 tctttatatt gttgccttcc agtgattcta tcaatggttt taaaactgga ataccacctg
    76621 ccacagatgc ttcaaacttg atgctaacat tatttaagtt agctaattct ataaggtcac
    76681 tacctttttc agccagtaaa tctttattag ctgtcactac atgtattttt ttatttaacg
    76741 ctcttgttac ataatcaaaa gctggattta atcctccaat tacttcaact agtatatcaa
    76801 tatccttgtc aaatatatct tctatatcag tagttatctt atcaaaatac ttcttatact
    76861 tgtgtttttc tttattttta actaaaattc caacaacttc tatatctctt tttgaagtat
    76921 tattttctat taaatcaatt aatccacttc ctactgttcc ataccctaat attgctatct
    76981 tcactgtaac atacccccat cattttgatt atattaaatt atttatatat ataaatatac
    77041 caataaaaaa agcttgagta taaactcaag ccatatgacg ggtttatact catctttcag
    77101 cataaatgct gcaggattta gcaccaatgt ataattaaat atactggttg ccgggcttca
    77161 cagggccagt ccctctgcca ctcttgataa gattgctaat ttaaatttat gtttaatagt
    77221 ataatacaat ttcttccaat tgtcactatt tttttaactt atttccctaa aaggatataa
    77281 actattatct aacagctctt ttagttggtt tacccttttt tgtaacatta ttatttttag
    77341 tctttgcttt cgcctgttca tgtcctggaa aaagtatttt aggctcttca atattcctct
    77401 tgtaaatagt aaatttaaaa ccaatagcct gcacaaattc agctcttaaa gcttcacata
    77461 ctgcattagc agtttcttta gtatcaagac ctgcattttc taatatagta acttttacta
    77521 attctctagt tcttaacata ccatctaatt gctctaagaa actctctgta acaccttctt
    77581 taccaatttg tgtagtaggc tttaaagtat ttgccaaaga tcttaaatac gccctttgtt
    77641 ttccttttaa catattctca cctctataat tctatactta aattatctat aatctatatt
    77701 taaattaatt gtaaaactca aattctaatt cataaatttt aaccacatct ccatcttcta
    77761 ttcccatttc tctaagccta tcaaaaacac cttgactctc catagctttt tggaaatatt
    77821 gaagggattc catatcatca aaatttacag aatacattat tcttctaagt gctttacctg
    77881 taactacata cacaccatct tcaatatcta tacttaactc ttcttcagta ccaatatcaa
    77941 gttctggtct atacatttct tcttctgaaa ctagctccac atcttctact tcttttagca
    78001 ttttagaaac ataggctatt acttcatcta tgccttgacg agttgctgct gacattttaa
    78061 atactgtata tcctctgcct tctaattcac tcttaaactt ctcaaactta ctctcatctt
    78121 ctaatatatc aaatttattt gcaactacaa cttgtggtct ctttgaaagc ttttcattgt
    78181 acaatttaag ctcatcattt atcttgtcaa aatcttcaat agggtctctt ccctctaatc
    78241 cagatatatc tacaatatgt atcaatacct ttgttctctc aacatgtctt aagaactcat
    78301 gacctaatcc tatgccttca gaagcaccct ctataattcc aggtatatct gcaagtacaa
    78361 aactatctcc aaacttagtt tgaacaacac ctagatttgg tgtaagtgtt gtaaaatgat
    78421 agtttgcaat tttgggttta gctttagtta caactgatag aaatgttgat ttacctacat
    78481 ttggaaatcc taaaagacca acatctgcta tcattttaag ttcaagagtt atccatcttt
    78541 cttctccatc tgtaccagat tttgcaaaag ctggagcttg tcttactgca tttgcaaagt
    78601 gttggttacc tttaccacct ataccacctt ttgcaactat agctgtatct ccttcttttt
    78661 ttaaatctgc taatacaaga cctgtagcct catctcttat tactgtacct gctggtactt
    78721 ttaatactaa attttctcca tttttaccag ctctttttcc tttgcttccg tcgccaccat
    78781 tttgagcttg atattttttc tggtacttaa agtccattag agttctaagc cccaaatcaa
    78841 cttcaaatat gatgcttgct ccacgaccac catctccacc gtctggacca ccagctggaa
    78901 cgtatttttc tcttctaaat gctaccgaac catttccacc atttccagcc ttaacaaata
    78961 ttcttgcctt atctataaac aaattcttca cctacttaat taaaaacttt taattagcat
    79021 taccaaaaat accattataa attcatcagt attataagaa aaaggagtgc ctcaacactc
    79081 cttttatgta tattactcag ctattgctac tggatatata ctaacttttt ttctcttctt
    79141 gtcttttctt tcgaatttaa cagtaccatc aactaatgca aataaagtat catcactacc
    79201 ttttccaaca ttagttcctg gatgtatttt agttcctctt tgtctaacta ttatacttcc
    79261 agcagttact aattgaccat cgaatctctt aacacctaat cttttagata tagaatctct
    79321 accattttta gaagaaccta cccctttttt agatgctaat aattgtaaat tcatgtttaa
    79381 catatggagt caccccctac ttttttaaaa tttttatatt ttttgggtat tcccgtttaa
    79441 tttctttaac cgctaattga aagtgattta gtaataattg tgcgtctttt acatgtgtat
    79501 ctttgactat acactctata tgaccttctt ctcctactac tttttcaaat tcaatcttct
    79561 gtaatttgtc taaagaattt ataactgcaa tagcattaga tgtaactgca gcacatacta
    79621 tatcatagcc tatttcagca aaatcagcat gtccctttaa acaaaaacct tgcaacaaga
    79681 aatcatcatt ataataatat ttaactttta tcataactta accaataact aagcgtttat
    79741 tttttctaca actatcttag tgtatgattg acgatgtcct tgttttcttc tgtaatcttt
    79801 ttttgcttta tacttgaaaa ctataacttt cttagcttta ccttgttcaa caactttagc
    79861 ttgaacagat gctccttcta ctactggaga acctaatttt aattctccat ctttagagca
    79921 agctaatact tcgtttaaag taacaacatc acctgcgtta gcttctaatt tttcaacgaa
    79981 taatacatca ccttcagaaa ctttatattg ctttccacca gtctttacta tagcgtacat
    80041 taaatacacc tcctcggcct caaactcgcc agtacaaggt acttcatttg aagatttaaa
    80101 cctttactgt gcggcattac aattattaat tataaaatat ttacatttta ttgtcaacta
    80161 ttttatcgaa aataacattg gttttattgt gctttaatgt actatttgcg tttaaagaaa
    80221 tctttatatt atatttttca ccaattttat caattatatc catataatat tcttttattt
    80281 gttcaaaaat aaaatcatta aattctacca ttatgttttt gtaaacagta tgttcactta
    80341 ttctcataat ttctttttca atactatcta gtatataatg tacagatttt attgtttgtt
    80401 caccatcaca acatggacaa gacattaaat aatacttatc aatggattct ttttctctac
    80461 gcctagcaac ttctactaaa ccaagttttg tcatacctaa tacttcagct tttcttttat
    80521 ctttattaaa ttcttcttct aggatgtgta aaatctcctt ttgatgcttc tttttatgca
    80581 tatcaataaa atcgattatt attatcccag ctatgtctct aattctaagc tgtcttacaa
    80641 tttcttttgc agcttcaaga ttagttttat aaacggtttc atcaagttta ccagttccaa
    80701 taaacttacc cgtatttaca tctataaccg taagagcttc tgttttttca attattaaat
    80761 aacctccact ctttaaccat acttttttat ttaataattt ttctatttta gattctattc
    80821 tgtataaatc aaatacatct ctattttcct caagacacag tttatcaaca taagtcttat
    80881 ctatacctct taaaatagac ttaagttcag agtacttatc ataactattg gtaattatag
    80941 attcaatatc atcattcaca ttatctttta catatttagt tgcaaaatct aaagacttat
    81001 ataataattt cggacctata ccaagtttat attcttttaa aatgttttca tactttaatt
    81061 tcaactcttc tatatctttc tttatttcat catgagtgca accttgagcc tcagtcctta
    81121 ttattaatcc tagattttcc ttatttactg ccttagtaat tttttttaat ctaaatcgtt
    81181 ctttttcatc agtaatttta tttgatattg tagttctatc attggaaggt atatagacaa
    81241 tataccttcc agaaatacta atctcagtgt ttaattttgc gcctttagtt cctatttctt
    81301 ctttatttat ctgaaccaaa atatcctgac cagattttat agtacttccc ttttttaatt
    81361 gtaaataagc aagtttctta aatccaatat ctacaaaaca agcttctatt cctggtataa
    81421 ctttttttac gattccacga tatatattgg atacagtctt cttatttaaa ttgtcttcaa
    81481 caaaaagttc tgttaatctt tcatcttcaa gtactgctgt tttctgggac cctattaggg
    81541 actcaataac tatctttttc acaacttcac ctctcgagct tacataggag tcactaattc
    81601 cccatcttct aatacatata aatctcttct caatatatca acatctaatg ggtcaatatc
    81661 aagttcaaac atctctaata tctttggtat aagtatatta gtatttaaat tagtttttga
    81721 gcctgtagct atagtagcag taagagtaat atgttcatct tctaaattta aaacatcaaa
    81781 ggttcttatc ataggtctta tatctacttc aaccatctta ccttttttat tcttttttgt
    81841 tatgattatt tctttattat tcataaagtc aattactttt ctttttacaa actctttcgt
    81901 cataggtctt ttcaaatcta tattaaacaa atattctcca tagtctatca cagaagaaag
    81961 agaaggtgtt tgtctatcaa tttcttttgc tttgataaaa tctatcccat ctggaagttg
    82021 aattgatact ttatttaaaa attcctctac tgataaatca tcttcttcta tttcaatatc
    82081 tacatactca ccttgacttt ctgcccctaa agccaaagca ttgccataac tcattttagg
    82141 gtgaggatta aatccttgag aatgtgataa gtttatttca gctcttctaa acgctctttg
    82201 taacaatctc tgaaggtcaa gatgtgatat atatatcatg tcgccttcct ttttaaattt
    82261 tactcttatt atcttactca tattagcaaa gcccccttcc tatatcatgt atatttattc
    82321 cacaaccatt gcagttatgt ctacaatcag aagtgatttt ttctttttta gcattttcgt
    82381 cttctctaat taagaatttt ttactaatac ctacatctat atggtcccaa ggaaatacct
    82441 cttcatagtt tctatttcta tgtgcataaa aatctataga aagattattc ttttccatag
    82501 cttctttcca tatatctaaa ttaaaatgtt ctgcccatcc atcaaattta gcacctagtc
    82561 taaatgcatc atatataact tttcctattc ttctatcgcc tctagctact actgcttcca
    82621 tcaaactagt ctttgaatca tgataattgt attttatatt gttatttctt aatttattta
    82681 ctaaatgtct ctgcttatta ataacttctt ctgtagtatc ttgaccatgc cattggaaag
    82741 gtgtaaatgg ctttggtaca aatgtagaag tactcactgt aacactaaaa cttctcttta
    82801 gctttcctcc atttactttt ctataaatat caataacttt ataagccaat ttagctatac
    82861 catctaaatc ttcataagtc tcagttggta aaccaatcat aaaatacaac ttaacactat
    82921 tccaccccat ctcaaaagct ctttctgttg cattttccaa atcttcttct gtaacacctt
    82981 tatttataac atctctaagt ctttgagttc ctgcttctgg agcaaaagta agtccagatt
    83041 ttcttacttg ttgtatttta tcagcaattt ccattgaaaa attatctaat ctaagggatg
    83101 gaagcgaaat cccaatatta ttagatgcat attcatctac caaataatca gtcaactctg
    83161 ataacttact ataatcactc gtactaagtg atgataatga tatttcatca tatccagtat
    83221 tcttaactaa tttatctaat atttctttaa gtcttttaac actcttttct cttattggcc
    83281 tgtatatcat acctgcttga cagaatctac atcctctagt acatcctcta aataattcta
    83341 gtactattct atcatgaaca gtatctatat aaggtactat tagtttttct ggataatcta
    83401 cagtctcaac atcttttatt atccttttag taggattttt agtaatccct tctctattag
    83461 gagttacact ttgaactgta ccatcttcat tgtacttgac atcataaaaa cttggtatgt
    83521 atactccttc tatgctagat attttatata aaaaatcttc tctagtcgtt ttatttttct
    83581 tccattcttt atactcattt actacttcta aattaacctc ttcaccttca cctaatatta
    83641 ctacatctac aaaatctgct aatggttcgg aattataagc acaaggacca ccaaccatta
    83701 taaatgggtc ttccaaagtt ctttcttctt ttaatattgg tatattggct aaatctaata
    83761 tatttaagat attagtgtat gaaagttcat attgaagtgt aaaagtgaca aaatcaaagt
    83821 ttgttatagg ctctcttgac tctaatgcaa ataatggtat acttttttct ctcattatat
    83881 tttccatatc aactgcagga gaatacactc tctcacaaaa tacatcttca tccttattta
    83941 ttacatcata taatatatga ctccctaagt gactcatacc aacttcatat aaatctggaa
    84001 agcaatgtgc atatcttatc aattcactat tactagtatc tttatgaatt gaatttattt
    84061 catttccaag atatctagca ggcttttcta ctttttttaa gatttttttc aagtctactt
    84121 tattcattta ttaaaattcc tccaaacaag ctctttattt ttattcttat ttataagtaa
    84181 tattatacac gataaaatat tttctatcaa aaatataact aaaatattga atttaaaata
    84241 catattattc acaaaataga atagctaaaa atatttaaga atattttcta ttaaattttt
    84301 attgaaatac aattttttta caaagtatga tatattataa acataaaact attgttttac
    84361 atgacttatc atgacatctt ttgtttcatt cacctcaaaa tggggtatgt tacttatata
    84421 atgataaatt ttaggagggt taaaaatgag taaagttttt gaagtaaaaa aagatatcta
    84481 ctttactgga gtagtagatg aaggtttaaa agtattcgac ataataatgg aaactgagtt
    84541 tgggacaact tacaactctt atttaatcaa ggacgaaaaa acggttttat ttgacactgt
    84601 aaaggcaaat tttaaagatg agtttttaag taatttatca gaggttactg atatagctaa
    84661 aattgactat gttgtaattc atcacacaga accagaccat gcaggtagtt taaaatactt
    84721 attagatata aatcctaata tagaagttta ttgtactaaa gctgctaaac tatacttaga
    84781 tggtcaaata aatagacctt ttaactgtca tgtaataaaa gatggtgaaa ttttaaatat
    84841 cggtaaaaga aatcttagat ttataactgc tccattctta cattgggttg atacaatgtt
    84901 tacttacatt gaggaggaca agactctttt aacttgtgat gcatttggtt gtcactttgc
    84961 aagtgttgat gcagaggtag tgaatagtga agattatcta aaatcagcta aacactacta
    85021 tgattgtata gttaagccat ttgctaaaca tgttttaagt gctgtagata aggtggtagg
    85081 actaaacata gaatttgata ctatattgac ttctcatggt ccaatgctta ctaaagaccc
    85141 aatggctgct gttaaaagat atgttgagtg gtctacagaa gctgttaata caactaatca
    85201 aaatcaagtt tctatattct acttatcagc ttatagtaat actttagaga tggctaaaaa
    85261 gataaaagaa ggacttgata aagaaggtgc aaaggctgaa ttatatgatt tagaagatat
    85321 gacattaaca gaaatgcacg atacattagt agtgtcaaaa gtaatattac taggctctcc
    85381 aactataaac aaaactatgg ttaaacctat gtgggattta ttctctgtta tagacccaat
    85441 ggctaaccaa ggcaagatag caggagtatt tggttcattt ggttggagtg gtgaaggtat
    85501 aactatggct gagactttac ttaaatctat gtcattcaaa atgcctgtag aatctcttaa
    85561 gaaaaaattc ttccctagtg aagagacatt aaaagagtgt atggcatttg gtgcagaatt
    85621 tgcaaaatta gttaaatagc cattaatcaa acataatatt atttaaaata aatgatttta
    85681 tatttaaaaa taaattaaaa tggagttgtc tcaaaattaa tttttctaat ctaattttaa
    85741 gttcaactcc ttttttattt tccaaaatga ctaatataat aataaatgta ccctttcgca
    85801 cagggtgcat tatttatagt ctgttctatt tgtatactag tatacttgta ttaattcacg
    85861 tatctagtat atgctactag ccctattcca gaattagatg ttgtttcacc aatttctact
    85921 ttaataatta tattattttt ttacactttt ttgataattc tgctgcagaa aggttcttac
    85981 cagtaaaatc taaagaaaat gccttatcat actcaaaagg ataactaaca ggtttgctct
    86041 ctggtgctaa tgcaaccata ccatatggtg tattcataaa ccctattaca gtaactgtat
    86101 gctttgatgg gtctaaattt gaatttttgc ttgtaaactt aattgtattt attgatgagt
    86161 tgattaaact acacggaact ccctcataca tttcaatttt tggacgtaga ttatttccat
    86221 aaacttcatc aagtattgcc ccttgttgat ctgctatcat agtgtgattc ccaggtccaa
    86281 ctggcgcaga aggcttagct ggcgtaggtt tcttaacagt tggcgttgga ttctgtgtct
    86341 ttactacttc gccaacagct ggatatgctt tcttgtcaaa tggtaatggg tgagtaagac
    86401 tcttgtatat gatgtctgct cctgctgatt tgttggcatc aatatctaca tgatacaaac
    86461 gtccatcctc aaaacgaata agattccact gatggtcatt tgttgtacta tgtacataat
    86521 aacattcaat tcccatagca tcacataaag ctttcaagct cctacacatt ccagaacaag
    86581 cacctttttt agtaaccaat gtataagcag tattggctcc ctctgctgcg ttccagttaa
    86641 catatgttgt gttgttttta atgtgattat gtatagatac aatccactat ggagaaatat
    86701 aaaagaaaag aatataacaa acaataaaaa ataagatgat tcaaatttta ttttgaaaca
    86761 tcttatttac tctacaaatt aaaattattt ggtgaattat ttaattatta ttttttatta
    86821 aagaaatttt aaatcttaat ataaaatacg ctattataca taataatcca aatacgaatg
    86881 ctactggaat taacatctcc gattcaaaat aaaagaaata ttctaagaaa atatctggat
    86941 ttactatatt cccattcttg tctaaaaaat cttttccatt atatcctaaa tgctgtataa
    87001 aattacttat gttattataa tctgcttccc tctcatatac catattagca ttcaatccag
    87061 aagaacttaa attagtgttt ccatctttca tatctattac atatagtcta agagctttga
    87121 ctttactata cttatcttta tcaagtattt tttcaagttc taacttatat tcaccaatct
    87181 ttgtcatatc atgtctttct gccaattgct ttatttctcc atcaagttct tttcctaaat
    87241 tatacatatt atgttgtaaa ctattattgt aataccacat aaatccagaa attaaaaatg
    87301 caattatact tatgtaacct aatacttttt taaaccccat tacaattgat ttatgcctat
    87361 ccaatgataa agatagttct tttattatat tacataattc atactgcatt tcatcaccat
    87421 catcaaatct ttcaattgct tttttacatg cttcttcttc atctaatcct tctaatttaa
    87481 attcatttgc agattctata agatggcatc tcatttcctg ttttaattct atagtacttt
    87541 tattgtcaca ttttttatat agtttatcta aatattcatc tattagtttc ataaattaat
    87601 ccacctctcc caaaaattga ttcataacct ttttaataaa tctccattct tgtttcttta
    87661 tttctaaaaa atctttacct tcattagtta aattataata ttttcttctt ccacctgaac
    87721 tttgttcatt gctataataa gatttaatta aatttttaga ttccattctt ttaagtgcaa
    87781 gatacattgt tccttctttt aattcaaact cacttctttc tcttacttgc tttgcaattt
    87841 catatccata acaatctttc ttttctaata tagaaacaat taatatatcg atataacctt
    87901 ttaacacttc tttatttaac tgcattatgt accaccgcct tttcacctac tactctataa
    87961 tgtatagtac ttatatttac tataatatta catagtactc tataatacaa ggtttatatt
    88021 ctacaataga cttaaaaata ataaatagct gtatattaat atttaatcta taaatactaa
    88081 tatacagcta tttatcaaat tttaaaaata aatttttgtt ttattaatgt tgtcataaca
    88141 acatttactt ggttgaaata gtattaccta taagtttaaa tatatataat aatagacttg
    88201 attctatttc atattattaa aatagagtaa tagtttaaat tctactactc tatctataat
    88261 ctatttccta attatttaat ctcaaattta gctcttcatc atttaaatct ttcataagat
    88321 ttctacaggt actagattta ttccaacaga aaaactaggg cattaaacac ttatatatct
    88381 gtttctttag actgtaatat taatattttt taaatacgtt gacttttgct ttttctaact
    88441 tctctccatg atagttctcc tctatcaaga gcttttataa atatttctgc tgaagctaga
    88501 tttgtagcta ttggaacatg ataaacatca caaagtctta ttaacgcttg tatatctgtt
    88561 tcatgagcct gagatgtcaa tgggtctctt aaaaaaataa ctaaatctat ttcttgtgtt
    88621 actattaaag aacctatttg ctggtctcca cctaaaggac cagatgctaa tctatttata
    88681 tttaattcag tttcatccat tattcttttt cctgtagttc cagttgcata tagtccatac
    88741 ttttttaaaa ttgattcata acctatacaa aatccgacca tagtgttttt catttggtca
    88801 tgtgctacta atgctatatt catatatcta atctcctcaa tttatgttta gatgtattta
    88861 aatttagaaa tttattttct ttcttctcat acacacattt agtactaatc ctaagtttgc
    88921 taaagatgtc aataacgaac ttcctccata acttacaaaa ggtaatgtta ctccagttac
    88981 tggtattaac gcaaccgtca tacctatatt ttggattatc tggtaaccaa acattcccat
    89041 aacaccaacc actatgaggg ttccataaaa atcttttgca tctcttgcaa ttgctaaaag
    89101 ccttaatagg aatatcataa ataagattat caacactgcc attcctatta caccaagttc
    89161 ttcacctaca acagcaaata taaaatcact atcttgtaca ggtaaaaaat cttcttgatt
    89221 ttgacttcca ttgtaaagtc ctttaccagt tacgcctcca gaaccaattg caatcagaga
    89281 ttgcataact tgatagtttc cttttagagt tacatcttct ggatttagaa aagcttctat
    89341 tcttaccttt tgatggtctg ccatcattaa atacatcagt ggcattgaca ctaatagtat
    89401 gattattcct ctttttatca actttgaact aagacctgct gtgaacagca ttgcaaatat
    89461 catacaacaa aatacaattc ctgttcccaa gtctggttgt gcaatcaata atccgataaa
    89521 tggaagagaa taaactacaa caggcataac ttcctttaac gtatttaatt tatccttttt
    89581 ggattcaagt atctttgcat aacttagtac aaatgttaat ttgactattt cagatgtctg
    89641 caagtcaagt ggtcctaagt taatccacga cctagctcca ccttttactg tcccaattcc
    89701 aggtaataaa actatggcta acaaaataag acttattata taaagcgctt tataatacct
    89761 gcctagaagg ttatagtcaa aaaataatat gactataatc attcctatac caagtacaaa
    89821 agctaatcct tgtttaatca attgattata tgaacctgtt gaattagcat gtgttgcact
    89881 actaagtata acaagcccaa aaataaagat agctaatact gtaactataa gtttccagtc
    89941 taactgtttt atcaacttaa ttgtcgactt ataattaata ttgatttttt tcaaagaatc
    90001 accgtctttc tatctttaaa catataatta aataaaaggg gcatatacca ataaggatat
    90061 ccccctttta agcactaatt acatacatct atcttttata ttctttagtg gtatattagc
    90121 aactaatgca gatacaggtt tgtcatcatg ctcacctctg catttagaca tttttatttc
    90181 aagaccatca tcttctattt ctgcataatt agctattact ttcaaaatgt ctgtttttat
    90241 catctctaaa agttgtggtg aacaatctac tctatcatga actaaaacta gctttaacct
    90301 ctctttagca acagatttac tagttttagc ctcgttagaa aaaactctaa ataaatctaa
    90361 cacagatgta tcctcctttg ctacttagcc atgctaaaca tttttttaag tctaccaaag
    90421 aatccatctt caacttcaag atcaagtaga ggaacttctt catttagtat cctttttgcg
    90481 atatttttgt atgcttgacc agcaagtgac ttagaatcaa gtatagctgg ctctccttta
    90541 tttgttgata taattatgct ttcatcatca ggaacaagac ctaacaaatc tattgctaat
    90601 atttctatta tatcttgttt atccatcatg tctccacgct taaccatatc atttctaatt
    90661 ctatttataa ctaatcttat ctcttttatt tcatttgctt ctaatagacc tattattcta
    90721 tcagcatctc ttactgctga tatttctgga ttagtaacta caatagctct atctgcccca
    90781 gctactgcat ttttaaagcc ttgctcaata cctgctggac aatctattat tatatactcg
    90841 aaagattctt ttagtttctc acacaggtca atcatctgct caactgagac agcattttta
    90901 tctctagttt gtgctgctgg taataaatat agattatcaa atcttttgtc ttttattaga
    90961 gcttgcttaa gcctacaagt tccttcaact acatctacta tgtcataaac tattcgattt
    91021 tcaagaccca ttactacatc taagtttcta agtccaatat ctgcatccac aactactgtt
    91081 tttttatttt ctaggcttag cgcagttcct aagtttgctg cggtagtagt ttttccaacc
    91141 ccacctttac cagatgttat aactataact tcgctcataa tactaccccc tatttttctt
    91201 tctatttgtc taactttgac aaatagcttt cgattacaat tcttccatta cttacaaagg
    91261 ctatttctgg gctaatttct gattcacttt cataattttc ttcatcatct ggagcttctg
    91321 caatattatc tgctatttgt aatattttag gattaagatt tccagcaaca acatatgcaa
    91381 attcattgcc ttctgcacct gcatgtacaa aaccttctat tttacccatt acaaaaacat
    91441 tacctcctgc tacaacctta gcaccagcat ttatatctcc cataacaact gtatttgatt
    91501 ttgaaaggac ttttgaacca ggtttcatat cattcaatat aactacatca ccttcaaatt
    91561 caatattttc accagatctt agggtattga catattttgt tggaaaatta ctattttctt
    91621 caattttttg atcttcaaca aattccacat caaatctaga agtaattcct tctttaagtt
    91681 ctagaatctc catgtcagtt aaacaatcac tattaatttt actaatttta gccccattaa
    91741 aaaagccaac atatgcttcc aatttgttta ttattttttc ctgtatttcc tcaaatggag
    91801 cttctctttt tatatttact attatccctc ttttattacc cttgaactct actagttctt
    91861 gactacaaat ttctcttaaa gacataacaa cctccagagt gatatatcat ttatattctt
    91921 caaatacgct ttaaaccctt ttattttttc tatataaagc taaagtttat acatagattg
    91981 agctatctat taatttgtga ctcgaaattt atattttcgt cagaagaatt gttaacatca
    92041 ttcgtcttgt tgtcattttt actattagtt ggctctaatc ccatataagt tccaataact
    92101 tctctagttg gtaaaagtga gaatacactt gaatcacctt gaggaattac acatacaaca
    92161 gctatttctg ggtcatctgc tggagcaaaa gcaacagtcc acgtaaaaga accataatct
    92221 tgtttaaatc tatctatttg gtcatctgtt atttttggat ttaattcttt tatagctttt
    92281 cttagatatg aagaattcac cttatcagtg tcctctaatc taacttttac tccatcttct
    92341 aattcttcct ctaatttctt tctttcttcg tctttcaaat ctttattttc taatttcttt
    92401 tttatttcct tttccttagc taatgaaagc tctttttctt tttctgcttt catcttatca
    92461 gctagtttaa tcgcatcatt taggttgaca ttataagatg acatatgact ttttaaatat
    92521 tcatactcgt tatctgtagg tattttccca cttttctcag ctgtaccagt ttttgctgct
    92581 acatctattg gaaaatcagc aaaagcactc ttcgctgtac cttgtcttgc aaccaatttc
    92641 ataccttttg ttaattcttt taagttatct ggatttttaa aaggtatttt ttcgactttc
    92701 ttctggtcat taattttaac tgatgaataa tcacttgaaa cagctctatc aactacagat
    92761 aattctacta aattacctcc atttgctata gcagctacat atcttgatat ttgagctggt
    92821 gtataagcat tttcaccttg acctatagct aagttaaatg tatctgcagt actccatttt
    92881 gcaaagttaa aataactaaa tactgctaaa tctgctactt cttcaattct atcttcttta
    92941 acatccaatt tttttagcct attcattgtt tcaactctac caggagtttt cttttctgct
    93001 gcccagctta caatctcatt gattcttttc tcatattctt taggattttt ttctctagtt
    93061 atatcaacaa aatcatttgc catttctctt tctaaatttg actttagaag agcttgtgtt
    93121 gatttcaatt tatcttctgt gctaggaact ttacctgctc tttcttctac ttcatcttga
    93181 agccctgtat tttggtcaag cccaaataat tttgcatact caagtatttt atttgcattc
    93241 atatctatac caatgctttt tccatctggc catgttttac ctgtaccaat tgttgccata
    93301 tatatattac aagactcttg tattgcttta tataagtttg tcataccatg gtttcctcta
    93361 ccatggttcc atacatagtc accaaaagat tttttaccta acattataac cccagggtca
    93421 tttatagtaa agtttggatc cagaccattt tctaacgctg ccattgaagt taccatctta
    93481 aatgaagaac ctggctgaaa ttccccttgt gtaaccaagt ttaaaagtgg acttcctgct
    93541 agtaagtcat ttggattttt tggttgaagt gctttataat cctctgtaga aatacctttt
    93601 gcaaatttat ttgggtcata attaggataa cttgatgaag ctaatacttc tccattttta
    93661 acatcaatag ctataagagc tgctgactgt gcttttcctg catatgcact aattggtttg
    93721 tccccaaatt tacttttaaa agtacctcct ttagaagcaa cttcgattat ctgttttaat
    93781 gcattgtctg aaacttcttg taaatcttta tctagtgtaa gatacacagt atctcctgat
    93841 ttaggttttt tagattcaat ttctttactg attctaccca atgcatcaac tttaaccatt
    93901 ttataaccat cagttcctct taatctactt tcattactct tttctactcc tgcaagacct
    93961 accatatctc cagtttcata acctttttga aggtatgatt ctatttgagt ggatggcatt
    94021 tttcctacat atcctaacat atgagaagct aatgacccat taggataata tcttactggt
    94081 tctactgcta ttgaaacacc aacaaggtcc atagcacttt cttcaatttg agcaatcgta
    94141 gtttctccta catccttagc aatagttact ggattatatt gagaatatcc ttttgatttt
    94201 atcaaatccc ttacgaccat tatttttctt gcatcttcat cactcaaact tttatcaatt
    94261 tctaatgcat cactatttct tactttttca aacgcttctt tggcactcag tttagtttct
    94321 tttatcttat aactagccaa ccaatctctc ttatctcttt ctgctgtgaa catccattta
    94381 ctaactaaaa taggtggata atatccattt tcatttagtt ttgcctgtaa tcttgtcgca
    94441 tccaatcttt tatcttcttg agataatatt ccagctgata taagtttgtc caccaagtaa
    94501 taaaaacttt ccttagcatt ataatcattt ggaataccat tttctgattt atattcccta
    94561 atatctctgt catatgtata atagtacttt ccattttcta catatatagg aaactcatct
    94621 acatattctt caccatttct ctccagcaaa tttataagtt ttaatgatat ttcatttgct
    94681 cttgaatgct tatttgcatc tttcttatta atatcgttac ctgaaacttg aacagtaaat
    94741 aagtttttat ttcctgccaa cagtcttcca tatctatctt ttatttctcc tcttggagct
    94801 tctattgcca actttttata tgttttattc tcagctaact cattgtaata ttcatattta
    94861 aatgtagtca tatagattat ttttactaaa atagctaaaa atatcacgcc catgactatc
    94921 ttaattattt ttagtctatc aacttgttta ttttcttcca tgaaatcacc aactaatctt
    94981 ctttaagttt taaaactgct cttttagata agcgatatat tactaaacca attaaactat
    95041 tcactattgg tgctactagt agacctttta caaaaagtgt tgatatgttg tagctttgat
    95101 aaattatact agatgtacct atattgacaa ttgaatcaat taaactgcct ataaaaatta
    95161 aaacgaaagt aataatataa ctacctttat atagctgatc tctcatgtat ccaattgcat
    95221 atgcaataat aaacaaaatt aatgcattta caccaaaaat tccaccaacg gttatgtctt
    95281 taataagccc tattattgct gctataatcc caccttctaa ttcatctaaa taaagagaga
    95341 ttatggttac atatataaga actaaattaa agcttatgcc aaaaatatct atataatttg
    95401 ttatactatt ttctatagtc ataagcacaa tccccaacag acaaagtaaa acttttttca
    95461 ttgtttttat cccctttatc ctatatttct tggttctatg actacaacgt catttatatt
    95521 cttaaaatca acataaggtt ttacaactac atattttaat gacttatctt tatcatcaac
    95581 cactttttca acttcgccaa ttggtatacc atctgggaag aatccaagac ctgatgttgt
    95641 tattatatct ccttgaatta cattatatga tgagtcaaac atatatcctt gcaaatatcc
    95701 tttactatta taactatctt tattatctaa agtagtattt tgagtaattg tacctttagc
    95761 attggcatcc tttgctagtt taaagcttac agatgcctta gaatccaata gtgaaattgc
    95821 cttactataa ttgttggaaa cttcataaac tatgccaact aatccactac cattcataac
    95881 tatactttct ttttttacac ctgaattttt tcctgcacct atgacaaaac tctcatacca
    95941 gtttccatca tttttaccaa caacacttgc tgaaatactt gtcgccttat actcttcttg
    96001 tacaaagttc agtgtctttt ttaactcttc tagcgattct gttttatcta gtttggcatt
    96061 taaagctatc atattttttt taagtttttc attttcttct tctaattttt ttaccttttt
    96121 agaattatct ttaaaatttg ctacatcttt aaaaccattt ttgataaaag aaaatccatc
    96181 atttattccc ttacctacac ttgtaatagc atctgaagct actcctaaat ttactggact
    96241 accactagaa aatttaccaa ttgatatacc cacaattcca attaaagtga tagcaactac
    96301 gcccgttgct atcactttaa cattaatcct ttttttctca tttttgttct tgtcaaatct
    96361 caaggccatc accaacttct aattcttagt attcatcatt aatacttttt caaagatttc
    96421 ttggtcttca acagatttac ctgttccaag tgcaacacaa tcaagaggtg tttctgctat
    96481 ttgtacagac ataccagttt cctgtgtaat aagcttatca agacctctaa gcaaagcgcc
    96541 tcctcctgtt agcattattc cgttttccat tatatctgag gctaattctg gtggagttct
    96601 ttctagtgta gattttattg catctactat tgaacttaca ggttctttta atgcttctct
    96661 aacttctgta gagcatattt ctattgtttt aggtaatcct gagattaaat ctctacctct
    96721 tatttgcata tttatttctt catcatcttt aaatgtagaa cctatgttaa tttttacatt
    96781 ttcagcagtt ctttcaccta tcataagatt atattctttt tttacataag ccactataga
    96841 ctcgtcaaat tcgtctccac ctattcttat agatttagca gtaacgattc ctcctaaaga
    96901 tattacagct atttctgaag tacctccacc aatatcaact accatattac cttctggttc
    96961 ttcaactttt aatccagccc ctatagccgc tgccattggc tcttctataa ggaatgcatc
    97021 tttagctcct gcttgtcttg cagcctcttc tatagctctc ttttctactt ctgtaactcc
    97081 aaaaggaaca catatagcta ttcttggact tacaacacct tttttatcag ccgctttttg
    97141 tataaaatag ctaatcattg attgagttat gtcaaaatca gctattactc catctttcat
    97201 aggtcttata gctactatat ttcctggtgt tctacctatc atttttttgg cttcttcacc
    97261 tactgctaat acctctttac tatcatctct tattgcgaca actgatggtt ctctaacaac
    97321 aataccttgt ccttttatgt aaactaatgt atttgcagtc cctaaatcta ttcccatatc
    97381 ctttgtcatc ttattaaaac taaaaaaacc ttttttttct ttcttttttt ccttagccat
    97441 gattttactc cttcctacta ttaagaatca tgtttaaaac attcttctat tattttatca
    97501 catataaagt caaattatca tattttcttt aaagctaaag tataatccat ctccaataat
    97561 tatatggtct attatttcta ttccaattat ttctccacat ttaataagtc ttgatgtgat
    97621 atttttatct tctcttgatg gttctacact tcctgaaggg tgattatgca tcactattat
    97681 cttacttgca cttcttctta tagcttcttt aaaaacctct cttggatgga ctaatgacga
    97741 gcttaaagtc cctatagata catctacatc agatattatc tcattttttg tgtttaaaag
    97801 aaccgcttta aaaacctctt tttttaaata ccttaggcta tccatataat acctctgtat
    97861 atcccaagga ttccttattt tatactttat aggtttaaaa ctagctactc tagagcctag
    97921 ttctaaagct gctttaattt gggttgattt tgataaccca attccatcta tattacacag
    97981 ctcctctatt gtcatatctt ctaaatgtct aataccctga atatctctat ttattatata
    98041 gttggctaat tcaatagcat ttttattctt gttgccagtt cttaaaagta tagccaacaa
    98101 ctcagcattt gataagcttt ttacgccttt ggcaagcatc ttttctctgg gtctttcctc
    98161 tggtgccatt tcttttacct taatggttga attaaatgac tttttcagat aaatcacact
    98221 ccataaaaaa gatttatact aaaatatttt tttaataggt cgcctaacct tgaaattgga
    98281 agaccaacta tattaaaata atctcctcta atttcttcaa ctaacaaagc tccataacct
    98341 tgtataccat aggctcctgc tttgtcaaat gactcattag ttttcagata atcctcaata
    98401 tcctgctctg ataacgtttt aaatttcaca ttgctgatta catagtcaat taccttttta
    98461 tcttcgcaca agtttattaa gctaatacct gttatgactt gatgctctct tccagatagt
    98521 ctttttaaca tatctcttgc acaagactca tcttttggtt ttcctaaaat agcattgtct
    98581 aaaacaacaa ctgtatcagc tccaataaca acatcttcat tatgttcaga tgctacagac
    98641 atactttttt caaaagctaa tctcataact aaatgttttg gtgtttcacc ttccaatata
    98701 atctcatcaa tttcattttt aattatatca aatcttacat tcgtattctc tagaatttct
    98761 ttccttcttg gagaggctga tgccaagatt atattcattt attcacctca tttgtacgta
    98821 atttgtacct atttagtcta tcactatatt gtaaaaaatt caacagaaat gtcgaacctt
    98881 ttttgttaca ctattgttat atttattacc attagaataa atatacataa aatagaggta
    98941 tggaaattat tccatacctc tgttttatgt actcattaga gatatggaaa ttattccata
    99001 tccttatttt gtccatatta caaaatttta atagctttct ttggacattt ttccatacat
    99061 aaatggcatc ctacacattt atctgcatct accttatgtt tttcttttaa ttctccctct
    99121 attgcatcaa acttacattg ttttttgcac actgtacatc caacacaaag ttcttggtca
    99181 atagtaactt tctttttctt agttatgtca cctgatatta cttttgtagg gcattttgct
    99241 acacattgca tacaacctac acacttatta gggtctatct tagctatttt gtcttcaaat
    99301 attattgcat caaatttaca agcttttaca cacattccac agccaataca tccagcagta
    99361 catttttctt taacagcttt accaaactct ttgctattac actctacaac tacttcttga
    99421 ctttctggtt ttgtgattat tataccctta ggacaaactt ctttacattt tccacaattt
    99481 acacactttt cttcatctat tactgctatt ccatcaacta tagaaatagc atcaaattta
    99541 caagcatctt tacatgttcc aagacctaaa catccaaatt tacacatctt agcacctgag
    99601 tttaaaacat ttgctgctct acaatctgat attccttcat actcatattt atcttttgca
    99661 cttgaacaag ttcctttaca aataactttt gctacttgtt tctcacctgc ttcagcactt
    99721 attcccatta tttctccaac ttttgcacca acatctgctc cacctacagg gcaaccatta
    99781 actggtgcat tgccttcaac tatcgcattt gcaagacctc cacaacctgg aaatccacaa
    99841 cctccacagt tggctcctgg aagtactcct agtatagctt ccactctctc gtctacttct
    99901 acagcaaact ttttagatgc aaaatctagt actatcccga agattaagcc cataattcct
    99961 aaaactaata cagctgtaag tatcaccatt ttcacccctc ttttttatag ctttataagt
   100021 cctgtaaatc ctaagaaagc tattgacatt aaacctgctg atataagcgt tatagggaaa
   100081 cctttaaatg cttctggtat atcagctaat tctagtcttt ctcttatacc tgcgaatatt
   100141 actattgcta aagtaaatcc agctccggct ccaaatccgt ttattattgt ttctactaaa
   100201 ttataacttt tttgaacatt aactagagct ataccaagaa ctgcacagtt tgtagttata
   100261 agaggtaaat aaactcctaa tgcttgatat aaagatggac tcatcttttg aattaccatt
   100321 tcaacgaact gaactataga agctataacc aatataaaag ctattgtttg taagaatcca
   100381 gttccagttt ttactaataa aatctgtata aaataagtta taattgaagc tagagttaaa
   100441 acgaacgtaa ctgcaactcc catccctact gctgtatcaa ccttcttaga aactcccaag
   100501 aaaggacata tacccaagaa ttgagatgtt ataacgttat taacaagaac gatacttaaa
   100561 aataaaagta ttaaattcat ttattacacc tccactatgc ttttttactt cttaatttat
   100621 taaatcctgc aaataagaat cctaatgtta agaatgcacc tggtggtaat ataaatatta
   100681 atactggttg gaaagatgct ccaaataatg tcattccaaa taaactacca tttccaagta
   100741 attctcttac tgcacctatt attgtaagtg caacagtaaa tccaagacct tgacctacac
   100801 catcaactat tgaaggcata gctcctgttt tgaaagcaaa actttctgca cgagctaata
   100861 ttaaacagtt aacaactatt aatggtatat atataccaag agccttatca agagcaggaa
   100921 catatgcttt taaaagcata cctactattg taacaaatgt agctataact actataaata
   100981 taggtattct tatcttatct ggtgtaattt ttcttattaa agatataact aaatttgcac
   101041 atattaaaac tgctgctgtt gaaagaccca taccaattcc atttattgct gaagttgtaa
   101101 cggctagtgt tggacacata cctataactt gaacaaatgt tgggttctca tctattagcc
   101161 catttttaaa tactttagct aaattcataa ttaaccctcc ttatttatta agagcactat
   101221 tgaaaacatc tatagcagca tttactcctg tagtaactgc tgtagatgta atagttgcac
   101281 ctgatattgc taatatttga ttatctgctg ttgtacttcc ttttgctact tcaagaggct
   101341 cagcagtttt tcctttgtat tgacccttaa atgcatcatc cttagctttt gctccaagac
   101401 ctgctgtttc tgacatatta ccaatgtcaa cacctgtaac ttgaccttca gatgatatac
   101461 ctaccataac ttcaatttct ccaccatatc cacttggttt agcttttaaa gtatatccaa
   101521 ccacttcaga accatctaaa ccttcataca cttcagctat aagaccatct ccaaggcctt
   101581 tgtaagtatc ttccttcatt tctttaaatt cttttgcttc tggaaggact gcttttctaa
   101641 gttcattatt tgcttgtata tttctttgtt ctattactgg agctgtaacc tgattagtag
   101701 ctccaagagc taatgcagct attgcactta tagcaagtaa agtaccacct aatctcacca
   101761 tactgttcat tatttagcca cctccccaaa tactctattt ctaacaaact tatctataag
   101821 tggagcaaga cagttcacta atagtattga gtaagataca ccttctggat atccaccata
   101881 cattcttata acagttgtta taagaccagc taatacagcg tatattattt gacctttttt
   101941 agtcataggc gaagttgtat aatccgtaag catgaagaat ccacctaaca taagtcctcc
   102001 agcaaacagt tgatatattg cgaaagttat attaaatcca cctaaaagga atgttaatat
   102061 aaatacagtt gctatgtaaa atactggtat aacataattt attatgcctt tatacattag
   102121 gtatactcca cctaataata ataatattgc tgatgtctca cctatacatc caccaatatt
   102181 ccctatcatc atgtcagcaa gactaattcc attgctagaa aggtctgcca gtcctgctgc
   102241 tccatttttc aaaaagctta atggagttgc tgtagtaact gcatctaaat ttttacctat
   102301 ccagttaaca cctggttgag tccaagcagt cattgctact gggaatgatg ctaataaaaa
   102361 tgctcttgca gcaagtgctg gattgacaaa gttacatcca attccaccaa ataccatttt
   102421 aactactaat attgcaaata ttcctcctac tagacacatc caccaaggaa gtgatgctgg
   102481 tacgttaaat gctaataata atcctgttac aacagctgaa aaatctccta tagtactttt
   102541 ttgcttcgta aatttttgat ataaaaattc agtacctact gtaccaagta tacaaaaaaa
   102601 catagcactc aaagcattaa gtctaaagaa gtatactcct gctactgctg ctggaaggag
   102661 tgctataata acttgtttca ttatatatga agtatcttca ttacttctca catgaggaga
   102721 agatgatact atcaacttat tttccatcgt ttttccccct taactttctt tatttctgag
   102781 cagcttgctt tcttctcttt gctcctattt ctctctttgc tgatcttata gattgaagta
   102841 atggtcttct tgctggacaa ataaatgagc aagacccaca ttctatacaa tccattgctc
   102901 tatgatattc agctgtgtca tagtcatctt ttaaagaata tgcacttatg aaaagtggtt
   102961 gtaagaatga tggacataca tctgtacatc ttccacatct taaacagttt tgaatatctg
   103021 gagtacgtga ttcttcctca tccaaacata aaattcctga agaacctttg ttagtcgcta
   103081 tttcagtagt atattgagct attcccatca taggtccacc cattataacc ttaccaatct
   103141 tcttatcttc tttaaatcca ccacattgtt ctattatttc tgaaactaat gttccaactt
   103201 ttgttattag gttctttggc tctttgatgc aactacctgt tattgtagtg attctttcaa
   103261 ccaaaggcat acctgtttta atagacttag ctatctgtgc tgctgtggca acattgtcaa
   103321 caactgcacc tgctgctatt ggtaatccac cagatggaac ttctttgcct gtacacgcat
   103381 aaataagttg tttctctgct ccttgtggat atttcacttg aaggccaaca acttcgattt
   103441 cgctatagtc tttagctaca ttttgaattg cttctatagc atctggttta ttcgtttcaa
   103501 ttcctataaa tccttttttg acatctaata ccttcattaa tgctcttaaa ccaaacacaa
   103561 catcttctgg attttcaacc attaatctgt ggtctgcagt taagtatggt tcacattctg
   103621 caccatttaa tataactact tctgccttgc tatctggtgg aggagatact tttacatggt
   103681 tagggaatgt agctccaccc atacctacta ttcctgcctc ttttatgata cctactatat
   103741 cttctttgct caaatcctct aactgacctt ttggttgaac actctcatgt aattcttcct
   103801 taaagtcatt ttcgataact acacattgag ctgaacctcc tggtacttca tgttgttcaa
   103861 tagcaataac tttacctgat actgaagaat gaacgttaca tgaaacaaaa ccttgttgtt
   103921 cacctatttt ttgcccaaac tttacttcat caccaacttc aacaataggt ttagctggtg
   103981 cccctatatg ttgctgaaga ggaatgtaaa ctatctttgg agcttgagct ttttcaagtg
   104041 cctttgtgtt agagtactct tttctatatg gaggatgtat ccctccctta aaagttaaga
   104101 gtttcattgt tttaccccct tatctataaa aaaacatttt ttctgccttc tataagtata
   104161 ctatatatat taaaaaatct taacaattgt taaaaaaata tccgtatttt tataatttat
   104221 tttataaatc aacacctcta tattaagtca aattgaggaa aaggattgct taattaaaca
   104281 atccttttca tatagctttc taaagtccaa attttctgta ttttatttta tagaatttat
   104341 aaacatagag tactcctgca tggatgataa aagcagactt ttacttacac tatatttttc
   104401 ttcatttgct gcttttgaag ctgtatcaat tttttcattc acattcttta catactctat
   104461 taaattatct ttaaataaac gcatttcaga ataatcaatc ttttcagctt cttttgatat
   104521 attttgtgat attgcctttc tatttgtcaa aatagtatta tatttttcca tatctacatt
   104581 attttcagca ttcgaccaaa aacttgattc ttctttaaag tttgttatta atttatttaa
   104641 ttctttagat atactctcta tataagcgta gttacttgta tactctaaag acaacatagg
   104701 tgcatctaag tgtgataaaa atgcatctgg aaacaccttt cttacactgc ttatctgctt
   104761 tctaacatca ttttcatcaa aagaggaata ggtctgtatt ttttttactc catccttctc
   104821 cataactgaa aaaggtatgt cattattaac taatgatgtc tgtatttttt tcaaatcatc
   104881 attattatct attgcagcaa cttgaatagt atacatatcc cagccttcta tagtagctaa
   104941 tttgacttct tctggctctt tagtgttatt taccgctttt tctggattag tttcttgttt
   105001 atcatctgaa ttggtttgtg atttagattt tttccctttt tttattgaat ttaattcatc
   105061 agatatatct ttataagtta tatctgatga attatttaga aatggtattt tagccgatac
   105121 atactccaat atcttgctat cttttatttt tgtataagaa taatagccaa ttagacacaa
   105181 gcaagcaatc gttataacat atttacgtaa atcaatctta tgtctattat tattaaatcc
   105241 tctgtatatc gtttttcttc tattcattag tttgtccctc ccaaaattat attattaata
   105301 aagtatattt ttaagagtca caatttatga atataaataa ttatttcttc taatttttta
   105361 ataagaaatt gtacttacta aacaaatctt cttgcaccaa gtaatacttt agaccaatat
   105421 gaactagtta aattatccac tttaacctta ttaggattag tctgagtacc actacaatgg
   105481 ataaatttac tatttcctac gtatatacct acatgattag ttgttccatc accatcagtg
   105541 tcaaaataaa ctaaatctcc tggtgcataa tttcccatag aaattgcact tccaaaatta
   105601 gcctgttctc tagaaactct aggaatagaa acgcctacag aatgtttaaa aacatactgt
   105661 gtaaatccag aacagtcaaa tttatcaggt cctgaagctc cccattgata tggtattcca
   105721 ataagagtat atgcaaaatc tacgattgtt gaaccttttg ctgtagattt atctgaattt
   105781 ccagtaaatg atggctttga gttactatta gattgagaat tttggttaga tgatgaattt
   105841 ggtttttctt ttgtatcctc attagtctca gaaatataac tggcactcac ccatccaatt
   105901 gttccactcg ataactttac cttataccaa ccattacttt tagcttttaa ttcaacaaca
   105961 tctccaccat ttaattttcc tattatagaa tagcttgtcc caggaccact tcttacattt
   106021 aaactcacag cagatgttac cttaccattc ttgccttcaa ttgattcttc gctagatggt
   106081 tttttatcag aattattagt actatttgaa ttactagaat tgttcgttcc aacatcttct
   106141 gatgttttag aaatatattg gctactagcc catccagtaa ctccatttga tagttttatt
   106201 ttataccatc cattgctttg ttctagtaac tttactacat ctccattatt tgctttacca
   106261 actaatgaat agttagtacc tgcaccactt cttacattca gtctagaact cacatttact
   106321 ttaccatttc cactaatagt tgtcccactt gaagttggat tattttgact tgatgtacct
   106381 tcagacgaac cacttgttga tatgtatttt gcacttcccc atccaacaac agaactcgat
   106441 acccttactt tataccatcc attagacttt tctaaaatct ctacagtttt tcccttgtat
   106501 aattttgcta ccttatcgca atcagaactt ggtccacttc ttatattcaa ggcacttgct
   106561 gttactgttc ccttttcaag agcacttgca tttatggagc taacagatac tgctactgcc
   106621 ccaattccta aagctgctat agcttttttc actactatca ctccccccaa caaattttta
   106681 tagtcataaa ttcataacat tattatccat ttttagtccc tacaatttaa tgataactta
   106741 ttttcttatt aattgtaaag aaattataaa catatcctta aaattagtga tttttaggaa
   106801 gtatttcaat ccaataatta tctgggtccg ctataaaata aattcccata ctttcatttt
   106861 caaaacatat gcaatctaaa tctttatgaa gtttttttgc ctcatcaaac tcctcaactt
   106921 ctaaagccag atgaaattca ttgtctccta aattatatgg tctatcccaa tctctaagcc
   106981 aagttaattc taatgtatga ctagtaatgc catctcctaa ataaactaat ataaaacttc
   107041 catcttctgc ttccttgcgc tttacctctt taagccctaa agctttttta taaaaatcta
   107101 aacttttttc taaattagta acattgaaat tgttatgaca aaaattaaac ttcattttga
   107161 aatcactctc caatttttat tttttttata ttatatcatt attataaatt tatttaaatc
   107221 atattaagtt aaaaatttga atgatgatga ccaattacca aatcatggta aattatttaa
   107281 aagaatatgt caaaaaaaga ataagctctt tcaaatgcat aaaaaattta tacccaagtt
   107341 atacttaatc atgcaaattg gcagaactta ttctttaaaa ctctaacttt taagtttttc
   107401 tttaataata taatttatta ctttttttct aatatcttca gcattataat catcttctac
   107461 ttctatatcc aaaagttttg ctattgacct catatcttct ctagtctttg acctatagct
   107521 tgatattaat tcatctttta ttttctctgg ttctaaaaga tattcttcat ctcctctttt
   107581 gaaaacaacg tatttttgag catatgaact tctattgtag tatatatatc ttgatatttt
   107641 tcttaaaatt tgattatatg aaagtcgctt gttaatatca agttttaagt actctgaaaa
   107701 agcaaatagc tctttttttg atttaaataa tgcttctttc tttatagttc ttgatattga
   107761 agttacactt tcttgatatg cacacttttt taacattttt aaatatactc tattaagacc
   107821 aatactttga ttgaattttt ttatattatt attaataatc ttatccaagt taccttcaaa
   107881 gtattttttt gctccttttt gtgatacata actctcaagt tctttgtggg ccatatcaag
   107941 tatcattttt tttaaatcct ctttatatcc cctagattcc atgatactcc ctcccttagc
   108001 tatttatagt atattcaaaa agctcaagaa atgtgagtca ttacaaaatt tttttacttt
   108061 ttatgtatat attaatttaa aaggggagat aatagtaatg taaaatcaaa catactcaat
   108121 ctcccccatt tttagacctc tattactccc ccaatagagg tcttttttta gtttatcaat
   108181 ttctattcaa ttccctttag ttcaaatcct aattctgcta tcacttcttt taatttttca
   108241 atagatacat catctttcat atctacagat gcacacttat tttctaaatc tacatctaaa
   108301 acttcaatac catctatatc ttctgttaat gcagttttaa gatggtttac acaatgacca
   108361 caactcatac cttctactaa tagtttcttc ttcatttaat tacctcctta taccctataa
   108421 gggtattcta tcatatagtt tatacttttt aaatagaaat taatcattta atttgattca
   108481 ttcgatttta tatctaaatt agatattccc tcatatacat caaaatcatt tggagtaatt
   108541 ttacctttta atctactatt acttacaata tagttgtttc tcacagctaa acttataaat
   108601 gttgcattat cttttatata tgtctgtaca tctttgtatg ctttttttgt ttcaatttca
   108661 gacgtagaac ttgtaagtgc agacatatat ccatttaact tatcatcagt atatccacta
   108721 ctcgctataa tactacttgc atctggtata attgatagtt tccatccaac taatgctaaa
   108781 tcataatttt tagaattaag agcattttcc atatccttat ctgagagctg atttactgta
   108841 ctatttattc ctatagcttt taagttttca tttattatgt ttgcagtttt tattctctca
   108901 ctattatctc tgtttactat tatctttaag ttcatttcag aaagactttt ctttacttcc
   108961 tctttttctc tatttttttt ctcttcagct tcttttttga ttctatcttc ttctgctttt
   109021 ttaacttttg cttcttcttc tggcgtaagc ttctttgagt tctttttagc tgattttttc
   109081 tgatttttta ctttattgtc attttgattt actgagttta catttgcata ttctacctta
   109141 gcaagacact ctatcgcctt atctttatta aactctaaat ccttcatttc actattatag
   109201 tattttgatt ttgaattaag tggaaaatta actggagtag catcatccat ataaccttca
   109261 ctaataattc tatctttatc tatagagtgt gcaattgctt ttctaaaatt aacatctttg
   109321 aaaaaaggat tattataatt aaataataca cactcataat ctcttccttg atattttgtt
   109381 atattaaact ctttttcttg aaacttactt aaatcattta atgtaacatt ggttatatca
   109441 ctatcaagag ccataaccat agatgtcctt gcatcttcat taggcaccat acctactttt
   109501 atgttcttca tggtttttgg aacttcttca tagtaatctt tgtttacaga taaaaccatt
   109561 ccttctcttt ctgtatatga ttctatttta tatttcccat ttcctatcat attattattc
   109621 ttgtcattta catcttttga atctaaatga ttttgagata caattggaaa aattaaacta
   109681 tcaattgaaa aagcatatct agctttaaat tttattgtaa aatctttatc tgatttaata
   109741 ttcacagaag ctatattttt agtaaattca ttatatggac tatctgcact tttttgaatt
   109801 aaaccaatag tatagtttac atcatttgaa gtaacatttt ttccatcatg ccactttgca
   109861 tcttttagct ttatatctat actcattcca tcctgagcta tattatactc cttaactaat
   109921 tgaggaatta cattgtagtt ctcatctata gtaaataaac tatcataaac taaattcatt
   109981 atataaccaa cagacttatc agtattagtt ataggattta tagtttttgg agttaccatt
   110041 gttaagttta tatacttagc atctatagaa ctttgacttt gtaaacttga atcactacta
   110101 ctttgttttg ttttagtatt actacaacca gctaccataa gagttatagc taaaacgact
   110161 gttaagactt ttattctctt cattagtttt ttcctttctt gccatatatc ttattataat
   110221 gttcgtaatt attttttact ttttctacat attttgaagt ttgcttaaaa ggtatatcat
   110281 gtagattttc gccatcttta ctatattcat tattttctaa ccattttttc acattacctg
   110341 aaccaccatt atatgcagct atcactaaat ctaatttacc aaattctttg tataacttac
   110401 ttaaatacca acagccaagt cttatattag tctctgggtc gaaaatatcc acatttttta
   110461 aatttagttc ctctgctccc caatctctag ttatgtctaa tatttgcatt aatccttttg
   110521 cttccttttt tgaaacagca gaactattaa acttactttc ggctttaata acactgtaaa
   110581 ctatattttc atctaaatta aattctttcg aatacttttc tacatactct gaatattttt
   110641 taggatataa aaatttatgt attactttgc tttccattaa tagtgcccca aataagatta
   110701 taaaaataga tagaatcaat actttcttac tattcacgcc aattctcctt catgtactca
   110761 ataaatttat gtgctttact ttctaattca gttattgttc ccgaattatc tattatataa
   110821 tcaccatatt tggatttttc ttcctgactc atctgtgaat ttatcctact aagtgcttcc
   110881 tgctcactgc aattatctct cttttgtatt ctactaattt gtacttcttg tttacaagta
   110941 actactaata gcttgtcaac catatctaaa aaaccacttt ctaccaatat tgccgcatct
   111001 aacactacta tattttcgcc tttttttctc aatttttcta tttcacttat tattttttct
   111061 cttattcgtg gatgagtcaa gttatttaat tccttaagtt tttcttcatc actaaaaact
   111121 attttcccaa gagcttttct atttagagtt ccatcatcat tttttatact ttgcccaaaa
   111181 tggacaaata ctttttccaa taacaactta tcctcaaata tcttcctgga tataatatca
   111241 gcatccacta taggaatgtt aagatttcta aatatatttg ataggctgct ttttccacag
   111301 cctattcctc ctgtaagtcc taatatcaac ataaaatcac ctactttgtc tcataccaag
   111361 aactacctac atttaaatct acatctaagt gaacatccat atttacagca ttttccattt
   111421 cttcttttac tattttctta actatatcta tttcatcatc aattgcttca actatcaact
   111481 cgtcgtgaac ttgtagtata agttttgatt tcaaattgtt ctcttccaat tttttatgaa
   111541 catttatcat agcaattttt attatatctg ctgcacttcc ttgtattggt gcattcattg
   111601 caaatctctt tcctctattt ctttccataa aattgcttga ctttatttct ggtatatatc
   111661 ttcttctgtt taaaattgtt acagcatatc catcctcact agccttttct actgttgtgt
   111721 ccataaactc ttttatttta tggtatttag caaaataact ttcgatatat tctttcgcct
   111781 ttggaacagg tatatttaaa tcatcagcta gaccaaagtc acttttacca tatataatac
   111841 caaagtttac agctttagct gcacctctca attcactagt aacatcttcc ataggaacat
   111901 taaaaacttg tgaagctgtt ttggtatgaa tatcttcatg atgtttaaat gcttctatca
   111961 tattttcatc ctgactcata tgtgcaagaa ctcttagctc tacttgtgag taatcggcat
   112021 caaccaactt acagttatca tctgcaataa acacttttct tatttttcta cccatttcca
   112081 tttttatagg tatattttga agatttggtt ctgtagatga aattcttcct gtagtcgtta
   112141 tagtttgatt aaatgatgaa tgtattctat tactttctgg atttattata tttaaaagtc
   112201 cttcaacgta agtagaattt aactttacta tttgtctata ctcagttatc ttatctatta
   112261 ttggatgctt atctcttaat ttttctaaaa catctgcatt agttgaatat ccagttttag
   112321 tttttttaat tattggaagc tctaattttt caaataatat aacacccaat tgttttggtg
   112381 aatttatatt gaatggctct cctgataatt cataaatttc cttttctaat gtagctatta
   112441 tttctttaaa ttcaacactc aattcatcca atatactttt gtctactttt ataccttcat
   112501 actccatatg acctaagact tctactaaag gcatctctac atgataaaaa agaccatcca
   112561 tactcatatc cattagactt ctttccatca taggaactgt ttctttaact gtgcatatta
   112621 tttgacccat atactctgct aaatcctcaa attctaaatc ctcatagttt ttagatttaa
   112681 caccctttcc taataattct tcttttgatt taaccttttt tgataaatac ttcatagcta
   112741 ttgcactaca atcatatgag gtagatgaag ttgaatctat taagtactca gctattgtta
   112801 tatcaaaata catattttct aagtttatat tatatggttt taaagatata taatcatctt
   112861 ttaaattata tccatacttt ttaatttcat tatttgaaaa tatactatct aactttgaca
   112921 cttcatttga atctacataa tatatttttt ctccatctac acttataaaa atatatatta
   112981 tatttttttc aagtatatta ccttgtcctc taacagtttt taaaataact tgtccttttt
   113041 tgtttacttc atctataaat ttttctatat cttttaattt taatatttct attttttctt
   113101 ctacgtgttc tgtgtcatct gaatcgacca aatcaactaa tcttgataag agacttgtaa
   113161 atccaaagta tctaaattta tctaaaagtt catctttatc ataatcgcca aaaatcatac
   113221 tatctaaatc cacttctatt ggcacatctc ttataattgt tgcaagtctt ttactttgaa
   113281 tagctatttc tttgttttcc tctattttct tttttacact acctttaagc ttatctgtat
   113341 tctctattag attctctata ctagaaaact cttttataag ctttatacct gttttttcac
   113401 ctattccagg tactccaggt atattatcag acttgtctcc cataagaccc tttaaatcga
   113461 taaattgtgt tggagtcatc tcgtattttt caattacaga attaaagttg tattcttcaa
   113521 cttctccaac tccttttttt gttataagag tagttgtatt gtctgaagca agttgaatag
   113581 catctttgtc tccagttact atgtatacct tatatccatt ttcttctgct tttttagaaa
   113641 cagtacctat aatatcatct gcctcatagc catctatttc caatctattt attctaaatt
   113701 tatctaaaag gtcttttaat ggctgtaatt gttctgccag ttcatctggc attccctttc
   113761 ttccagcctt atactcttta tattctaaat gtctaaatgt aggtgctttt ctgtcaaatg
   113821 ctacacttat atgtgttggt ttatatatat ctatcatttt aaatagcatt gttgtaaatc
   113881 catatattgc attggtcttt agcccttctt tattattcat ttctggaaga gcataaaaag
   113941 ctctatttat tattgaattt ccatctatta taattaattt tttttccaaa ttatatcact
   114001 cctaaaaatt atctattttt gtaacatata tattatatac caatatactg ttatttaata
   114061 ttcccataat aataatagta tattaaaatt aaatatgttg caaacaatat atttttttgc
   114121 tataataata tacatgacat gcccgagtgg tggaattggt agacgcagtg gactcaaaat
   114181 ccaccggact aatactccgt gccggttcga gtccggcctc gggcaccatt aaaaactcct
   114241 aaagctattt attcaataga ttaggagttt ttttattttt gatttaaatt ttaagttatt
   114301 ttttgaaatt actgtgtctt tttaaaattt atataattat ataaatttat cttctagcat
   114361 taatttaaaa actaatttat ttttatataa ttttctattt tatatcataa cttattacaa
   114421 ctttttatct aatttattgt atacaacaac actacaaata aattgaaata aaataagcaa
   114481 tccaagaaca actaaaaccc acttgcttat taccattaca gaaaatacac tcaatataga
   114541 aacaataaat ataagaatta caagaacata ggacatgatt tgattagtga tacgtccagc
   114601 tttatcacgt aacataattc gtctttcatc attcatctct atcctttgat tttttatctt
   114661 ttcttcataa tctactgctc tttcaggttt actccaatac atatattgaa gaatcataca
   114721 tacacctgga cctaaagcag ctccagataa tccccaaata aaagcctcaa atgaaaactc
   114781 agtaaatgta gccaataaaa caagtaaaat tccacaaata aaatatataa ttccaacata
   114841 taacatattc tttttcattt ttactcctcc tcataaataa atatttcttc aatactcata
   114901 tcaaagtatc tagctatctt aaaggctaag atgatagaag gattatacct accattttct
   114961 aatgaaccta tagtttgtct tgatacttgc aaaatagaag caagttcttc ttgttttatg
   115021 cctctttctt ttcttatttc ttctaatcta tttttcacat ctatccccct ttaatatctc
   115081 aactacggaa agtctacttt ccataattat acaactatat tccatttatg taaagcttac
   115141 tttccatatt tacaaaaaaa taacagacta ttttcagcct gtaattttag aatttcatgt
   115201 tgtttattaa ttttaatgtt atttattaat tccatattat ttattaattt taacttggtt
   115261 tctgaattgg aatccaaact tctgtagtat aatcaggagc attgatatcg ccattgggat
   115321 aaagttcaat atctggtaaa ttagcataca catacccaga acttggtaac cactcagtaa
   115381 taattctttt ttgcaattcc tgtattgcca gagcatttgg cattggagaa acacattcaa
   115441 atactgccca tgtgcctgat ggtattaagt attcatgagt atcttctaat acaggcttat
   115501 ctgttggagc agcaatataa taatctaaac ccttactatt tgtacacaca ctaactccaa
   115561 gcaatccaca aggttcatta tttattaact ctgaaagttt atcaattgtt ccatttttta
   115621 tgcatttagc ccacaactta ggaactttct caaagcactc ttctacaatc atgttcatac
   115681 tttcttttat accaacaata cgaaaccctt tcttttctac aatacgatat tgcatttcta
   115741 tatttccttt tacataaatg cttaatgtca tcttaggata tgcttttaaa acaacaccct
   115801 ttgctctagc tgcagatgga gaaatgttat gtatattttg aaaagctcta ttaaaagatg
   115861 ttggtgaatc gtaaccatac ttctcagata gttctaaaat tttgatgtta ctgttctgaa
   115921 gttcaaatgc agccttagtc atacgtcttc gtctaatata ttcagataat ggtacttctg
   115981 caatatatga aaacattctt tgaaaatgaa aggttgaaca acatgcaatt tttgctgctt
   116041 ctgcataatc cactccactt tcgagatttt cttcaatata agtaatagct tgatttaatt
   116101 tatttatcca ttccatttga tattacctcc aagcaaatta tacagtttaa taaaataata
   116161 tacctctcta ttcatgcaca aaattgtaag catttaaatt tataagcatt tttcaatcaa
   116221 tacaataaat ataaaaattg tattatacaa taaaaaagtt caataacatt atattataaa
   116281 atgttattga actttttata aaaattaatt taagtgtagt taaattaagt attacactat
   116341 cttatatatt acaatatcct actatcttat agtcttctgg cactttataa tctttgtctg
   116401 gagtacctaa attccatttt aaatcaaaca tagttgcact tattattgtt gcaaaataaa
   116461 gcataactat accaatgtct attttttctt catataaatt agtatgacca tcttttctaa
   116521 cagctaaaac tacagtgcct ccatcaacta taaatctcca tggttgtcta tttaatgtag
   116581 atggagctaa tcttgcatag tgaaatgcat caagaagtgc tctttcttct aagatttcta
   116641 tacttgcaac atttccccat tcgttcatat aaacaacatc ttctacacct agtctagtag
   116701 accccttatc tgttacaact tgcatatcag attttgaata attttgccca gtttttgtag
   116761 catttaatac tttagcatta cttacatttt ctccatatcc aatagctata attcctgtta
   116821 cctctttatc tgaattaatt ccaagttttt cttttacctt ttttccatct tcaaaagtaa
   116881 cccaacaaga accaattcca agttctgtta ctttaaagat tatactttct cctatgtacc
   116941 ctgaattttc aatgtaatta tcttttatgt cagataatat tataatataa cttggagaat
   117001 ctatcatatt tcctttgtac cctgctactt tatctaaatt attaaaaact tcacttctat
   117061 tcataattct tacatcaaca tctatttctg gaactagttt cttacaagat tctgagtatt
   117121 tcttaatttc actaagatat tcttctttaa tatctgtgtt cttatattct ctaacagact
   117181 ttctatttaa tatgattgtt ttataatcca taattttatc ctccccaaac tagtattgtc
   117241 ttaattatat acccattaat atattatttt actcatttat ttaataaata aagattacaa
   117301 ttttgtaatt attatttatt aataatattc cacttttaca ttaataatga ccagttgtgc
   117361 aaaatccatt gccaaccacc aaataaaaac atattataaa ggtaatataa aataacaaac
   117421 aaatcttaac aaaaaattaa acttttttta cacgaaagaa ggcttcccgt tgccttcttt
   117481 atttttataa aaaaataagc tgtttctaaa atgatttcac atttttgaaa cagccaagtt
   117541 attctataat gacaactata atttgaggat gtgagggaga gttgtcatta taaatttagg
   117601 gtaattatat tatgttttaa gctagttctt tctatattta tataatacat tttatatatg
   117661 aattttatat gagattggta taaatgatat atgaaattac atatgtttat attatattaa
   117721 attttattat tacattttcc acaacaatac tcatatgtct ccacattatt tggaatattt
   117781 acaaatacaa attctttaca gttctcacaa tactttaata tagatatagt tccacaagtg
   117841 taacattcaa atattacaca atcctcattt tcctctacta tttcaaactt tttactatgt
   117901 tcaccacact ctgggcactt gtgattattt acattcataa atactcctcc ttattagtat
   117961 agttacatgt caaaaactta attaatgtat tctatattac ttattatata ttctataata
   118021 aatcatattc taatataata aaacaaatta aataaaaaaa aaccataaat tttaaattta
   118081 tggattaatt cttgtaatga taactctatt tgaggatgtg agggagggtt atcattacaa
   118141 tagggtatta tattatggtt tttaagctag tctttctaca cctcatatga tacatatgct
   118201 atatgaattt tatatgattt ttacataaat attttatgaa atttaaattt tttagtcatt
   118261 ttgaaatttg taaaaagttc tctaaaaatc cacagcatca taaacagcca aaatttaagt
   118321 agaacatcat aaaaaaattt gtccaataat tttaacaagt aatctcacct cattataatt
   118381 attgacacaa acttaaataa acaatctata aatcttctat aaatcttaaa ctttccccct
   118441 attgatacac aatttctagt ttgtcaattt tattttgcat ttctaagaaa atttcttcaa
   118501 cagaattgtt aaatatattg cctaaataga ttcttttatc tttttgaaat gaataagatt
   118561 ttacactacc atcagaagaa atatataaat gactccactc tgctccatat tttgaaaacc
   118621 tctcctttgt atctttaaac ctcatatctt ctatttttat tgctttttct ctgtctcctc
   118681 ttactacagt gtgacccctt tttattaaac tggttatttt tatatcttct tttaatttaa
   118741 tacgtgtatc atcatttttt gaatatactt tccatatcac tttatgacga taattatcta
   118801 attcctttat taagcttcta tcaatagtaa aactatcttt agttaccaca attaaatcaa
   118861 aatggtctaa catatattga aatatttctc tcatactttt attttttaaa atatcctcac
   118921 caataacctc tataaatcta cagcctttct catacatgca gttcaataaa cttgtgattt
   118981 cagaaaaata atcatttgta ttattatctc catctatttc tatagtaaag tacaaaggag
   119041 taatgtatga tttatttcct gttatctcaa atacacttga tagtgtctgt atatcatctt
   119101 caaacgttaa gtatacattc tcataaaaca taaaaaattc cataactttt tctttcatat
   119161 tatggatatt tctatatcta ttggataata tatttattat atcgtcagta gtatttttcc
   119221 catcacattc agccagtata acaatttgct tccaacttaa gctatccaca tttccgatac
   119281 tttttttata tccatcttct tcatcataaa taggaccaat tataatgttt tcttttggcc
   119341 acagatgaac cctagttcca tcttttaatt tcggatattt attttttaca gactcataaa
   119401 atctacttgt atcacccatg attctttact accccccata gtttaaatat tctatgctaa
   119461 aaatagcact ttatttttat taattcaaca attattcaaa attggtcatt atatatgttt
   119521 aaatggattt aacatcaacc ttatttatat gttattgatg tttatatatg ttatataaaa
   119581 tcttatttct catacttcaa tgtaatctta actatctctg gtttacaatt aagcctaatt
   119641 aaaacttttg agcctcctaa gcctttattt aaaatcatag tgctattatc tttttcatat
   119701 tttccccagt catacttagg aaagaactct ctatttggag ataatacacc tccaacaaaa
   119761 ggtattctta ttatacctcc atgaacatgt cctgctaaaa ccaaatctgc tccccatttt
   119821 gcatattttt caaagaaaaa tggtgtatgt gctaaaagaa tgttatattc attttcatta
   119881 actttaccta gattgtcttc tacaaaattg tcacttagtt ctaatttttt gctattagca
   119941 aataaatatg gatagcattc caatggtata attaaaccat ataaattaag atggctatta
   120001 cctctatata ttcttacaga ttcattttcc atatttatta ttttctttga atatagttcc
   120061 ttaaaataat ccttatatag atgtttatac ttttttatta aagatttttg ttcatgattt
   120121 ccaattatat gatatacttc atatttttca accaaattat ctattaaatc taatgcaact
   120181 tgaaaatttt tattttctcc atctactaaa tctcctgtta taaatataac atctgggttt
   120241 aatgattcaa ttttatctat caatacctta ttatttttat caaacacctt attatgtaaa
   120301 tcactcactt gaactatttt aaagttatca aattcctttg gaattttttt gttgaaaata
   120361 gtatattctg tcgtttctat atgctgagtt tcatacttat acagaatata caataatatt
   120421 aatactaata ctgtcattga aacctttata atcatattct cttcctcttt attctatttt
   120481 gttaatatta ttataatgct tttatgtttt ttttaaaaca ataacatcat cacatacata
   120541 taaatctttt cgacattata aaaataagtt atccttttct aaaattttca tttattttag
   120601 aaaaggataa ctataaaatt atctataaac ctctatattg tgaaatatag tttttccttt
   120661 atttaaattt ttatatatat gctctaaagt tccatcaaac ctaatagaat gtccagactc
   120721 taaaatataa gttttcccat ccacattaag gtcaagttta ccttctatta cgagtacata
   120781 ctcttctaaa acatgactgt gtgtagatga aacatgagta cagttttcct caagctcaat
   120841 tataaaaagt tcaaaccttc tttgagggct aaaagggtat attggatata acttcatgtt
   120901 ccctttttgc tcaacaatag gctctacttc ttctttcttt ataacctcat aggtatttgt
   120961 attttcattt aatagtgtag taaaatttat tttaaatcca gatgaaattt tccataaagt
   121021 agatactgtc ggacttgatt cacctctctc aatctgtcca agcattgctt tactgacacc
   121081 tgtcatcttt gaagctttgt ctaaacttat gcccatttct tgtctcaata accttaaatt
   121141 ttctcccaca ttaggaaatt tattatccat gttaaaatcc tcctgatagc tatttgtatt
   121201 ctatgatttt tactcctgta agttctacta tctcttttaa ttttaacata tgattgttac
   121261 aaatttcatc aaattcatat atataatctt caagccctaa tgccttatat ttatcgattc
   121321 caaatttatg atatggaagt aactccatct tgcctcctgg aacattttgt ttgacaaata
   121381 atgcagtatt tcttatattt tcttcactat catttactcc ataaataatt ggcactctta
   121441 taaccataga tttattcaac tttgaaagcc tacatatatt atctaatata attttattac
   121501 ttactcctgt atattcttta tgaatattat catccataga ttttatatct acaaatatgt
   121561 ggtctatttt ctcaaataca tcatttacct tattccaatc aaaatatcca caagtttcaa
   121621 ttgcaatatt tatgccttta tcataaaaaa tatcaactaa ttctcttaaa aaatcaatct
   121681 gaagtgtagg ttcacctcca gaaaaagtta tccctccatt agattcaaag aaaaatataa
   121741 aatctttttc aacttcctct actatttctt caacactcat ttcttcggtc attatacaaa
   121801 tggcatcttt aagacatacc ttgatacact ctccacataa atcacattta ttatttattt
   121861 gcgctctatc aaatagtgaa cttatatttt gaggacaaac atctatacat ctattacagg
   121921 atacacattt atctttcata acacctaatt ttactatgtt actccaggaa tctggattag
   121981 aacaccactt acattttaat ttacatcctt ctaaaaatat agtagtcctt attccatctc
   122041 catcatttac tgaaaaatgt tgtactttta caactctacc ttttttactc ataatctacc
   122101 tcataattaa aaattgctat gtgaatttct agctattata gcatcttgca tttctcttga
   122161 taaattaaca aattgagtac tatatccagc aactctcact aataaatctt tatattcttc
   122221 tggattttct tgagctttta atagagtatc atttgatatc gtattaaatt gtacatggaa
   122281 tcctcctaaa gcaaaatatg atttaatcat agatgttaga tttctaagtc ctctttcagt
   122341 ttccaccaaa tcttgattca gtcttaaatt tagaagtgtt ccaccagtat gaacatcatg
   122401 atttattttt gatgcagatt tcattgctgc tagtggactt gttgtatcag taccaacaaa
   122461 tggagaaact ccctctgtca aaggttttgt cgcttttctt ccacaaggag ttgcgcctac
   122521 gatttttcca gttggtacat agtttgatat acccataaat gcactattaa atttagagcc
   122581 aaaaatatcc ttgtattttc tagtttcagt ataataaaaa tcagaaactt caattgctaa
   122641 tgaatctaca taatcattat catttccata cttaggaaca tccaacgcaa gttttcttaa
   122701 ttcttcataa ccttcccaat cattatttag tgcttttgtt aattcttcta acgtagtcac
   122761 cttatcctca aatactaatt tttttatagc tgccaatgaa tttgaaacta cacctaaccc
   122821 tataccagtt aatacaggac ctatattata ttttgctcct cctttactta aatcaactcc
   122881 cttatccaaa catccatcta cacaagtaga taaaaatggt cttggtacca tttctttatg
   122941 aatttgttga gcaacagtag ttcctataac agaacttttt acaagatatg ctaattgctt
   123001 taaaaactca tccttaagtt cttcaaaaga agtaaattct gtgatatttt ttgtatctaa
   123061 ccccattttt tctccagtta atctactctt accttcattc atagcatatt ctaaagctgc
   123121 tgcaaaattg atatttacgg ctgaagtcca ctgtcctgtt tttctaaaat gaggaactac
   123181 acaaccacag ttactccaat ctctagcatc ttctgcatca tatccatctt gtaataacat
   123241 ttgtgcccct gcactatcgc tgtgtatagc agggaaacca gttccttgtt ttaccaattt
   123301 agcaactgcc attacgaaat tgtctggtgc tccttgactc actctaacac ttaatcctgg
   123361 ttggtgagtt tttacacttt ctgtagcctt taaacacata tatgagatat cattcgttcc
   123421 atcagtacca tttctctttt taccaccaac agtaagattt tggaattgat tatatcctgc
   123481 aaagtaattt gctgtatttg ctgatatagt ccatacccat tctgataact taatccaaag
   123541 tgcttctatc aattcttgag cttctgattc agttatttta ccttctctag catcattttc
   123601 ataatatgga tacatatatt gatcaaatct acctaaattt aatgccaatg gattttctga
   123661 tagaatacca cctaattgaa caaaccatac aaattgtatt gcttcataaa aattagttgg
   123721 agggtttgct ggtacattca tacatatctc tgaaattttt ataagttcta actttctctt
   123781 ttcatctgtt tcttgcttac tcatctcttt tgcaagattt gaatatcttt gtgccaatgt
   123841 cataataccc tgtgcaacta tagaaacaga tttgtaaaaa tctatctttt caatattttc
   123901 tgaaactgat atatctaatt ctttaatttt tttatctgca tcttccttaa tccctttata
   123961 tccttttaca aacaatatat cttgataatc tggtgttact tcaccaactg cctgtctcca
   124021 cttagaatca ttatctatta ttcctgtatc tactaatatc ttagctgtat cttctgggat
   124081 tcttgctaag aaaacttctt ccaaagattt tcccttccaa tatggaaata tttcttttct
   124141 tataaattct atttgttctt ttgatattac atatgggtct tgagttcttt tatcaaaagt
   124201 atccatttct ttgtctaccc attgccaaga aaactctggt gtcaatatcc ctgttcttct
   124261 aaattttcct gctgtaccta ctattaattc attttcaaag atttttatag gaagttcttt
   124321 acatgtctcc aaaaaagctt tagctcttct tatacagata gcttctccct cagttttttt
   124381 atgtgattct gtaaaaattc tagccctttc acaacatatc ataggtttag aattaatata
   124441 ttcttgtcta aatgcttcta ttctattagt ttgactcatt taaaatcccc ctttggataa
   124501 tatatactac atttttgtat gttataacat actttaatta tattatactg tcctttagca
   124561 taaaatggaa gcaaaataac ttattttttt tcatctacct tgaacaccta tatattaata
   124621 ctttttttgt taaatttata aaatctaaaa aaattttcta tgatatattt tctatattgt
   124681 tatagttatg tctaatatac taatgatttg aaatatcaaa tttgtatact agacttagtt
   124741 ttaaaacctt agttgattgt ttaactttgt taacttcaac atgtatatcc ttcatataag
   124801 gaagctctac aacacctact cccttattaa agtcttcttc aaccatagaa aaaatttctt
   124861 tctcagttaa gttcgtatca gtcaatgatt taaataaatt gtatataaat ttaacatatt
   124921 tatcactctc agataactta tcatcttctg gatactcttt agcacagaga atatctattg
   124981 ttacttttcc ttctttatcg tcttcagaca tagaatagaa taaacttcga atattttttt
   125041 caggtggttt ttcagcacca tttatagata ctacaaagct accatctgat tttgagttag
   125101 taatactata accactgtct attatagctt tcgaaaatct ttgagataaa tcttttttta
   125161 cttcttctct acctttcgca tcattaatct tttgtgagta attattaaat agctcaatag
   125221 attcatcttt tttatcttca acttgttctt tcaatgaatc tttactaatt tgttctgagc
   125281 tacttaagtt cttatcagat acaggagaca tacaccctac catcaatgct aagctaagat
   125341 ttaaagccac aattattgcc actctattta tattcctttt tactttcata cacaatcctc
   125401 ccatcacact aaccgctcta aagtattatt cattgcacta gaatatattt atattttctt
   125461 tatattaaag atttattatt caatacatat caccttccta tccaattctt ataacttact
   125521 attagtaaaa ttataagctc cttaatacag aaataaggat gttatctttt gttattaaaa
   125581 gataacatcc ttattttttt gtatcaatac atatgtccca actggtaact taatcgcccc
   125641 aactgtcagt atcttggtcc aatggtatat atatatttag tataaattta tcgatactat
   125701 tttcaaataa taattctcca ttatattttt gtaaagaaga tttaatactc tgaataccta
   125761 ttccatgtac gaacttatcc attttgtttg ttaacaatat atttttatta aaagtaagct
   125821 gatttagttt actattttca catttaagta caaaaaatga ccttgttata gttcctttaa
   125881 ttctaatata tttattaata ttttcatcca ctattttatc acatgcttct attgcattat
   125941 ccaaaatatt agaaaatatg cttgacacat ctataggttt tacaaaattt acttttgaaa
   126001 aatttataga gcaagtaaat ttaattcctt tttttaaaca tacttcactc ttttcgttga
   126061 ttataatgtc taatatcata tttcctgtat tatagatata tttaaatgtt tttatttcat
   126121 cttttaaatt gttaacatat tcattaattt ctttgctatt gtttctaagg ttgtctatac
   126181 aataaatgtg attatttata tcgtgatata gtttcttaac tcgcatatga gattcttgaa
   126241 tacttaaata atgcgcatat tgcatatcta acttattttt tattaattca gcttgagatt
   126301 ttaatctatt ctcttttatt atttctttaa acaatagtat aagaaatata ctactagctc
   126361 ctaccaattt tggattaaca aaattatcaa aatagtatcc ttctgaatgt aatgacccaa
   126421 accgttctaa tttttttaat acataattta caagcatatt cattgtatta actaataagg
   126481 caaataataa atatacataa tttctcttat cttggctaat taattttata gactttctaa
   126541 aaaagctaaa tataagatat ataagaataa ttattaaatt actatatatc tgaattttta
   126601 tagattctaa gtaaggtact aataaagatt ctttagatga aataacatta cctgtaattg
   126661 caaaaaatag tattctatat ataacagcat ccaaacattt ataatataca ctaaatagat
   126721 aaaagaaaat ggaatactta atataaccca tcttataaaa ataattatag tatcctcccc
   126781 aagcaataaa tgctaatata taaaataaat agtttatatt actaaagtaa tttcctccat
   126841 taaataatct acttatctga attataatat aaataagaaa caagacaata tagaatacta
   126901 ttttttcatt ttttttacta tcctttttat aaattaaaat tccgttcatt atagaaaact
   126961 gtataaatat agataaaact actaatagct cagtcataaa gtttagcata ttgtatcacc
   127021 aagaaatttt aagaatttct ccttaacttc tttatatcta tatctactaa taggtacctc
   127081 ttctccactt tccagtattg cagtattagg ctttatattt tcaacatatc ttaaatttac
   127141 tataaaactt ttatggcatc ttataaattt atatggattt aattcttttt ctattttgcc
   127201 taaactatat tttatatcaa aattcttgtt tattgtgtgt attagcatat cttttttttg
   127261 aacttctata tattttattt catttaaata aatcttatat gtattagact tattttttat
   127321 tgtaatatga ctttccttat ttatttcaat atctttgata caagttagca catgtttttt
   127381 tagttcttcc aactctattg gctttagtaa atacctataa gctcttacct cataaccttc
   127441 ttgcacataa tctattaatg aagttacaaa tattatttcc atttcattgt ctacttctct
   127501 aatctttctt gcagtatcca ttccatttaa tttttccatt tttatatcaa gaagtaatat
   127561 atctatatct tttaaattac tttccagtaa ctcttctcca gatatatact tttgtatctc
   127621 atattctata cttatatctt ttaatatatt ctcaaggtaa tcttctatta aaagttgtg
//
LOCUS       DAEHWO010000003       114821 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEHWO010000003 DAEHWO010000000
VERSION     DAEHWO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 114821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114821
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.003"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(43..582)
                     /locus_tag="KNP54_000258"
     CDS             complement(43..582)
                     /locus_tag="KNP54_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891193.1"
                     /translation="MLNEDVVKKLKNVPNNTNTEIEKVNTNIETAKTELNTKIDQLIA
                     GGSNVASTQTITIDDWVDDTENGFKATVTHGLLTQRIVVNIIDATTKENVVTNFKIID
                     DNSIEIRSETRSELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRFVNLEEK
                     VNGGLSNIATSVNELITYC"
     gene            complement(662..985)
                     /locus_tag="KNP54_000259"
     CDS             complement(662..985)
                     /locus_tag="KNP54_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891194.1"
                     /translation="MIKIDKEKIEKSRQRKELDDLDSSQKTQDNDITDLMLATAEICE
                     MVLSSQQTSTMSLKNIKLNEGGSSMAAIYVGLIERGLKTIDQVPVKYREEVRKMCEAL
                     EISLS"
     gene            complement(997..6276)
                     /locus_tag="KNP54_000260"
     CDS             complement(997..6276)
                     /locus_tag="KNP54_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891195.1"
                     /translation="MKKNKLLQRGSLFGNKEFKIEEFNKNFDTFNVKDIFTDMDSGSV
                     FIIKDDLKLYAAGYNVFGNLGLGNKVSPIRYFSKIDIDNVKYVSSSGTHSLLLKNNGD
                     VYSTGLNTDGELGLGDNIDRNTFTKINISNVKQIACGNGYSMLVTNDNELYVCGNNKF
                     GGIGLGNTSTVNTFTKIDNLSVKEIFAGVSCSYILTLNNELFSTGLNNYGQLGLNDTT
                     NRNIFTKVNLDNVIKISTAQGAVNFLLENGDVYGCGDNSSGQVGVGGGATVTVLTKLS
                     ISNVKNIESGRYHKFYIANNNDIYVTGANPDGRLGDKINCDRSTYTPRKSSISIKNIS
                     KIKCAHAISFILTSNNELYMTGDNNYSFSYLKRYDKFIYGFEKFEDFDIEECNHIESI
                     DNRLLINKNDERVLDIGLENNFVNISLVKANDTSTFIVVNGNELYAAGYNAYGGLGLG
                     HNRHCYEFTRVPLELEEGVTIKDIYLNLGSYFTFILLSDNTLYSTGYNVFGVLGLGDN
                     INRNTFTKVNISSVDKISVGDNHALLKTTTNELFSTGLNNYGQLGLNDNTNRNIFTKV
                     STVTYVNEIIAYSNSSYCIDNSRISYAAGYNVFGELSLNDTSSRSVFVKMKYLRYKTD
                     TTVSDVSNIAEIIPFNNGCLIRTTSNNYYVSGRHNYYSTSIKNSVTDDYYSRFGEFVG
                     SKNSNANEVAVLIDEPKLSKVLVSNYNLCLLLDASDGGYKEIKFTGRPSTFGASSQDK
                     NLGLRSLISSSMPYYNHYLGTDNLLYTTSKTRMESKFEIRGRNAGGQRGDSSYYSNSQ
                     KYTLSNAFFAYNSQVIYASRLRIVIKDYFGNIYCSGVNSHGCFGIKKPYDVRHDGFVN
                     ISKQFSKKYIISNIKEIKSDRQALYILLNNSEGYVCGNNAGNKLGTIKARSEFIKVPI
                     DNIKEFIPSNDCLFILTNNNQVYSIGTNDLGQLGLGDNIDRGTFTKVPIDNVKKVITC
                     YKSSYILTYDNELFSTGSNGYGQLGLGDNINRNTFTKVNISGTIKDIFCGRYVFIILL
                     ENDNIISLMGCGNRNYISSNTNSNSLTKINIEGLTDPSTISNLMLEEGKTIITMKNRI
                     FVTGYNSLGGLGVGTSYNNSSGYIEGYKDLAFNSNIKEVALGEYTIFVLLENGDLYSG
                     GNADDGIGFNESGTVVLKKLTSNIKHIYANGKNAYYIDNDNALYVFGSRQLGQINNYS
                     DVVQKTPVRNCLNVKQVYTQHNGLIVQYTNNKLEGKGNAVVGQVGIFNGHEENQIANT
                     SGDNPSDLSFSNEMSIIRNNYGLLVNKKIFLHNDDSINYRIPFGTNAGNYSTSLPFDN
                     IKKMSLSSTHSILILENGDVYGCGSNQFGELAINKSELTTTSEFIKINLTNIIDIACG
                     DNFTYFLKNDGSLFSIGKNSEYQLGIGHNDEVNELQEVLTISNIREIYAYSNYILAIT
                     TEGQLYVQGYNINGILGLNENTKNTIIKLFTKVLENVKYIKSYDDKHIFVIKNDKTLY
                     VTGINKETYKIKDVEIGSMLYTFSQIYIPRDVNDIVDALIKDETLYIISKVDSEKTCL
                     EIKNKSYSSIEIDLQNPNNELTKIEMFINNISSSIIEDLSTGTVTFEINPENLVLGEN
                     KIVFKAHSDIGNNLYINVYIYKKETGATIVKDSTVLIDGNTYNVSSIVDNSQDVVLTL
                     NKGLLEDLNSNNPIYHLVNKLKVQLKINESDTFKDMVKVETRKTENGYKEIYELKDMN
                     IQSAQPKVIVEEGNTNTTIKKPSMLFNLDVETL"
     gene            complement(6287..8365)
                     /locus_tag="KNP54_000261"
     CDS             complement(6287..8365)
                     /locus_tag="KNP54_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBF0891196.1"
                     /translation="MKNYEIKNHTIEVDFSNYRINKRLLDYFIYNENDVKTAYIEAIL
                     KNKDEIIDLSEYDRVLVSITKSDGQKVNGECEVVDAENGIVEIELSRQALASVGINTF
                     QLSLVKDGTLLNTTNLYYRVEEGMINDDDITSTDEYGVLLVIIAQAEEIIKNNKELTK
                     RVEQLEITILGNEEVRDKAEQIRIYNEDIRNIQEEEREFNELTRQNQEANREESIQNM
                     QIQVDDKLTDCQLQLDEMIDAKSKEIDNIVDDKMLDVQVQTDKKFQDLDTRANNTFDL
                     YDKTFEDKLTDNQEQIDYKLDEVNQAISNVEDCIDESTTKLDTKIKEVDDKIVEVNTA
                     KTDMTTTVSNKITEFENRFEELESLDARGELIQARESVDGTVKDTLKDRLTYDFEKVN
                     EKIAEMTSAATNVAFSKSYVESDWVADGEYFKLIVNHNLVTENIFVAILDEATKKSMT
                     NSYTTVDSNTIEIFNESNIDVKVTVVNGNTNKEVIQATINDNITTLDSTYSSIKIDAK
                     FDESLTKINENKSNIATNLEKINLIQSKVGSSELSTVSKNISDAVNELDASVKVLESG
                     GNTNEQLKILKENYNKMSVEILKILFELELDKEATADEAGYWYDTLYDSKNISNLDGL
                     KLNKFKQQLELLSNSGTVLFKNVTVPFLCNKIRYIHDLGSNYSETKTEESYQKGDTEI
                     KINKYSYEVR"
     gene            complement(8377..8532)
                     /locus_tag="KNP54_000262"
     CDS             complement(8377..8532)
                     /locus_tag="KNP54_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891197.1"
                     /translation="MEVNLQKAYTVAFEEIKSLYNELILYKALNMQQQEEIENLKKEL
                     EEQNKEQ"
     gene            complement(8534..10456)
                     /locus_tag="KNP54_000263"
     CDS             complement(8534..10456)
                     /locus_tag="KNP54_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HBF0891198.1"
                     /translation="MILDNSPADSWIRITGVIVTYNNTLYQVVDTETNKKYIYWDADN
                     PGTLKVSNVRLPEGNTQFLVVVNDNGKHTEVPINSSIFDISFDGNSRKNTEEQIWGLY
                     ETDEKHNEKFVVIEKDIDGIHQTVLEVQEDASHIKENMSLIDQRAENVNILVKEVTKN
                     FGGSQENITLRENINKAIIKLNADLGTFSSNMSNYFNDNEVTDEEKEKIDIELNLLDT
                     DKASLYTELQKLIDRTTGVDLVAINTSKTALDAASTNLNSIINSVISDSIITPSDRIL
                     AINANAQYNLKINELKNTVDKIYITGMGGSISEEFSQINATAKEIKLEVAKVDGATKT
                     NAAEIKLTKDDITMMVTRNNSGSIVGIKPDKIEFGFNDISNYVEISRSGLTVNQGAIA
                     CDILTTPSGHEPIIRLFGSSRSGFAIDARQSDGSSQASAIRLKYDSNNYFWVGYDTAE
                     IYVDGEEHFIVERDDTFVRCGGATFTFTNGDSLGVGYSFYPERSVTDLGCERYKWRYL
                     YARSTLSESDKKFKENIVYIKDIKNRTRSSITPTPFLDFIRDDFKPATFDYIAEKDRT
                     IADSQIGFIANDFKDSYVGKTFLYDYGEENGLMFSPSGYTTVVATALQEEIQKREELE
                     MIINELNEKINNLGGY"
     gene            complement(10458..12173)
                     /locus_tag="KNP54_000264"
     CDS             complement(10458..12173)
                     /locus_tag="KNP54_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891199.1"
                     /translation="MHFNVNLKQIKSDYTLTIHKMNKSFLGQIPINFLNSIKRELGGV
                     DEIQLTIPKYITDRFLFNKIINPIFEEVKEERLICLNNKEYFVVKNVVTTDDKLKVVT
                     AKSKEVKLGKIDVNIEDYGLQMFTKDEEASIISLNDYLKQETGWKLGYVDDSIAYETD
                     SEGNKREKVRWQESINSNWLDYFNNELKEQFECIADFDTYNNLVNLYHIDSFGDNIQL
                     YLSHDNYIKSLERTTNSDDIVTRLKLEGSEDMDIIGATVTGYDYIENYSYFLDNKEMS
                     EELSRAIKKYQEMNEIREPIWRELIDTKLKKQRERDSKSNEWLHVIETIKAKKDIKKT
                     YDNPEHKDEVNSAKLAVEISELEDKKVILDVQIKHLEEEIAKLDESIKDINILCKRET
                     STDEDGYLIFNEALLDELNEFLYYDTYTNDAFLKVEDLIAEGKRQLSLKCIPTKEWTL
                     DVINFLDRIIDINFRQHWKGDLSLGDIIVLHSKESKEEELVYFTSFTQNFKNGKLDTL
                     ELTLSNKKVKEDDKRTIADYLTKAEHATRTLNSKRHLFIQQQKKRINLPDEYIPKKNI
                     QKELM"
     gene            complement(12526..12681)
                     /locus_tag="KNP54_000265"
     CDS             complement(12526..12681)
                     /locus_tag="KNP54_000265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891200.1"
                     /translation="MINNIEDCKLLIEAEIRMKDIDEKELISQRDILKDLNINEKDLE
                     DIEVNFE"
     gene            complement(13831..19905)
                     /locus_tag="KNP54_000266"
     CDS             complement(13831..19905)
                     /locus_tag="KNP54_000266"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBF0891201.1"
                     /translation="MEDKRKRGGSVLHEYGVSLGDTVGMITATNEAIQNPEKVGNGLK
                     SVAINLAGMKVSADDGTLSLNKTAKGLKEIAGITIYKNKDTGELKNMVQLLDELKGKW
                     GELREDEQKGLAEAIAGKQQAAIFQSLMGNYETFKEIRSEFSQGLQFGSAEAENKQYL
                     DSLAGRLNELKTIWADIFQTVFNSNTTYGFLDGLISVSNGINSVIKTLERLKLTTPAL
                     IGSFMTLKTLFSGMGMTNGTRNVARLINPLNMIGTPIKATTTILQSFRHAVMAANVAG
                     ANGANVITRAGTGLGALRQSLSRTSIGIGTLNIATSLLNGAMIGLATFAITKGIQWID
                     DTIHKYEKLAEKQKEVIGTTTSEISSLQQKKKSLEGISEEYNNLASKTEKTADETERF
                     SELKQQIADIAPELVLGVDENNDPILNMSGNLDEVINKLRKAIEEKNKLLKSQEDELA
                     ITTSKTAPDTKKDLDKEKKKLDKVLEDEHNLFKNALSKSNFKEQTEALKKAYNQQETD
                     FAEHHQKLLTEYEKYNEEEEVMQKRAINRLTNSDISKTYAKQSEQKKSKMNELVANMN
                     WHDYSVGQQNSIISAFDKISESIPVEKLDQWNKKITDANINYQASGDMNQYTKELQGL
                     ANELQKLSGGSISADTWLIGLQQGFSGLDLASMKLHTFLKSYGSSLAELENKDSFAIK
                     LKNQFDALNDFSQDLEVNGKVNIKLLEDIQSGEAGQDLPQQLKDIINGFTFGEDSQIE
                     AQAQLALQVTTTLQNEGQLSNDVVKQLNDLFKGKLQLTDDILKNGLKISDKLPALPGN
                     MVQALNEQFANAFTGDNAPEITPSVNGEKAKKELKELEKFKKDTFKSDKIVTEINNKG
                     LDFAKKDLSVLKEQLDRFKNEDTKLSFTTDCADAFKDVNSLEEARKKISAPMSLKYDI
                     DVDKKGLTEAKKVYDILPDNLKKKIETEVIGIDKLDTLQNLIDKAPNKKETIFEIINK
                     NPDKLNEIDEILNNVPNDKKEAVIDFIVNNLDQLEKAKNVQEFINNLPPEIKKQLGIE
                     VEGGENAEKTVNTVQNADGTKADLLVNAEVNGESQVVECIETLDKNGNKTYTPNLNPQ
                     VNNSEKVVQCMRILDEYGNESYIPIVSPQVTNEEGLNSTKQKMDELDNKTVTPTVQIK
                     TEGETEVEQATNFIENTNPTKVIELSINNSGKDEIDNTKQKLDELNNEKATPTIEATG
                     AEQASEQLNQLSQKAQEIGQGNYHINVSTSTEQGAKNISGLIARVKQFLALKVSTLVF
                     RTETAQAAKNVSGLLAKVQSYVSRYGGKTIKTTFSALTATAAKNISGLIRKIESFKSN
                     YAGKTFTTTFVTNKVTNSSGGGGGGNSSDKTNKTERTSVTNGTPIPANLSQPRTSEPA
                     PISDETPVTKPSLFSRAVSRATSAFKVIKPKVTINNDTIDSSVKYSIELFKELENAIS
                     AVTNEIALLDKKMEHATGDEKIKYLQEQNKLFAQQKDLIKQQQDGYKAESNRLKNRLK
                     EKKMGFKFDDTGNLTNYEEKLISIEKELDKLNSKSGDKENKKDESRKKELEETKKVLE
                     EYIKVTFTELPKCEQEWEEYNNKIKEHNEELRKAQEEMWKLNKNSTWTSMYKDVEQVN
                     NEIAMIDVLLKNATGDEQIELLEKKKELMAKKAKELSETTAYLQETQKELQQKLQGYG
                     FTFRDNGDITNFIQHKNQLKKNMTDEEFKRMEDAAEGYLDLLINKIPDANKEIAESKK
                     EIEALNKEIQDAYKDQLKEAQSLQEKIRDMYKKELEERLKEIDKETKAKIDSLKKQQD
                     AYNDSRKEAKYKDDYEEQQDVISDLEKQIAIAERDSSLSGQKKLKDLQKQLKEEQKKL
                     QDLVQDHVDDQVNDMYDKESDRLQEEADKLKEELEKKYSDENLVDLINEAISSGKFVG
                     LDGEVEKLQDAIIEYINKYEDGMLAMGSVTKQEWLDTLKEGKETLEDINDILDELDLS
                     KFAMPNYNPPSNSRSRSAFPTSSVNFNSPFFVVQGNVTKDTMKDLEKFGRDLENRVYR
                     KIVENIKS"
     gene            complement(20509..21966)
                     /locus_tag="KNP54_000267"
     CDS             complement(20509..21966)
                     /locus_tag="KNP54_000267"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891202.1"
                     /translation="MVEEFKIKTSIELDDKDAREKIEKLKNSGQDKPIKLNLKIGELD
                     KLSQQAEQLKGIFNKAFKIDNTALSNLKQIESTMKEINKLSRRSQESLLGGGSGNTGN
                     INNEQQDLIRQYKEISNVVSRLQNQIRTGLGDSSIERTTEQIERLKRQLDSVYAQMNS
                     SSQARMDMFDASRATRDLADMNRNLSRIEDMATQASARLNGLGDNIDTDKVNRLRNEL
                     QELKQTASRNIDLNLDVGNIVNRIQEINQEVRNLERVDSLRSNFSRIEDSIRQAFGNE
                     RVEAFRRSLEQLQGSAGNLNGDFNNIFDRLTREMRDARQEAERLNNTVSRGGGFFNDF
                     YSSVASYSIGDMLGDALTDGIRSMKDVILELDSSMTDLKKDSTSELDRIREKAIQTAK
                     DVGMSASQVQESIASSLQAGIGGMQESIAAARQSMILANVGDMDVEGASSAVNTIING
                     FRIEPLKEMQVQVGNTTKKTTELTAAMDMLNCLAC"
     gene            complement(22046..22495)
                     /locus_tag="KNP54_000268"
     CDS             complement(22046..22495)
                     /locus_tag="KNP54_000268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891203.1"
                     /translation="MFKKILLILMISLLGFGVIGCSDSKEDTNEVVKKETEEKLDEES
                     TSEDIYNKKLQFLNDTKNQSEIIGDEIRLLTEKYNNYEIVKSDWKEDLISKKKIITDL
                     KSVLEEEKSNILDGVSDFQKTILQNKYNEIIEYYDYMLKGISQNLNI"
     gene            complement(22584..25811)
                     /locus_tag="KNP54_000269"
     CDS             complement(22584..25811)
                     /locus_tag="KNP54_000269"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019291.1,HMM:NF024352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HBF0891204.1"
                     /translation="MEKYLFNQKLLKEKYNMEIDLDLYDYKQRRLILEKWRDIIDNKS
                     IDKLNEIQLKEIFVSDILNKVLRYKSLTDNIMDYNIKPEEKTKIDGTRADIVLGYFSN
                     EESDYRVAIELKKPTTNLDAKQLRKNNHNTPVEQGFSYLPKYGRNCTWLIVSNFKEIR
                     LYNANDATEYEFFSIKDIYEKDDVFKKFLYLLSSKSLMTKHGKSRVEMLWEENIKQEE
                     AIEKGFYDLYKNTRLNLFNDILLNNKDILDVKTCLTKTQKILDRVIFVCFAEHKGLIP
                     ENIFETCIQVGKKSVSRFGVWEQVKGLFESIDLGNQEKGINQFNGGLFAEDYILNNLK
                     IPNKCFENLYKLSLYDFNSDLNENILGHIFEKSISDLEELKLEINQVNIKKKDSKRNK
                     DGIFYTPKYITKHIVNNTIRRYLDEKKKELGEDKLPELKEEDYETVVVGRNIQHKRVQ
                     VVEYKTDKIQKYINFWKNYRDVVKNIKILDPACGSGAFLNEAFSMLKKEAESVNEILR
                     DLTDGEISFFDLDANILKNNLYGVDLNEESVEITKLSLWLKTANKYSLLTSLDNNIKC
                     GNSIIDNKEVDCAKAFDWNVEFEDVMMSGGFDIIIGNPPYVSTKMIPEKHREYYWKKY
                     KDLLISEMDLYELFLYEFCENKLKQDGFLGFITPNTYFTNKSFENLRKYLLKNVCVDT
                     ILDFPYRFFPFEDVNKETAIIIINKKLPNIKNNINLISINKENMKKIKIFNSNTYNSE
                     NKITIKSIINDLDNKIVIQSNPIILKMLKCKHKLGDYLNLHKGWMSVPNKTICDGIIY
                     DKKILSSNDIKDNNQLNGILNKCLEGKDIHRYYIDKVDKFVNIENMDDKTMRWHKSPK
                     IITQRIVGQNQNKIIATVDIEGTIIFPSGNIINLIKEDNLEDIYFYIGVINSSLINYF
                     YNKFYGESNTNLTADAVKNIPIPNLKNVDKSIVINNSKILINKYGKLYLYTNKFLKNV
                     FKILSIDNNPSNKLYNFYLLDFDEFYNELSKKKKLYFKNIDELEEYFNKYKDAINRII
                     YDINVCENTINTFVYDLYGITELESKSIEDICKTTKDTVVTSLAY"
     gene            complement(27306..27743)
                     /locus_tag="KNP54_000270"
     CDS             complement(27306..27743)
                     /locus_tag="KNP54_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891205.1"
                     /translation="MVFKSLDELVAYTKNKIAASMPEVGKEMKEIVKEEVNKQVYSDY
                     APSLYDRTYELLNAIDVSEITSDSVATEIKDSGSWFDIYSKAHAFPMERFENGGVWGH
                     GSTKYNPVFRPRTNIMEESNSKAQERVPKCFKSKMNELGVPVK"
     gene            complement(27744..28193)
                     /locus_tag="KNP54_000271"
     CDS             complement(27744..28193)
                     /locus_tag="KNP54_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891206.1"
                     /translation="MNKIQVDKLIQDEVRAIIPIIDENGKEEYIEVRNPDKETKEEIL
                     NKIWVGMENPDLALSQEDILKMLIDKLTNIELNIEIEDLVDGNISSELENVMYYIGQI
                     ENELTASLLMNTEIKLGQMKNEILQDRVLKETEEIEKMNNIKEKVVN"
     gene            complement(28207..28992)
                     /locus_tag="KNP54_000272"
     CDS             complement(28207..28992)
                     /locus_tag="KNP54_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891207.1"
                     /translation="MVFLDDKFLFDNISSESMNIKLVTLGDDEILNEYGLPYEEAIKS
                     DSTFNKNPCYSEDETTIEPITLQFCLCSEHGEAYEWDDYTLENICNWFWQREFKPFIS
                     YDNIEEIYYLKARKIIKRYTKDKKGVLEIEFQPYTNYAYRSFQKVITVKDTREIKLNN
                     VSNVDEEYAPVIDIECLKEGDITIRNSTISDNEEDNLVISGLELNEKITIDNLYYTVL
                     NSSGENRFNIVNRKWIRLRRGVNILKFTGNCKVSIKCKYPIIK"
     gene            complement(29089..29907)
                     /locus_tag="KNP54_000273"
     CDS             complement(29089..29907)
                     /locus_tag="KNP54_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891208.1"
                     /translation="MMRFAIKDASNIIVKNKTTGEPLFYTADLNAFNFKLDSESVYAK
                     AKGANTIAFDGAITASLALEQEVIQMPQLAMLLASDMVEESAKVGKRKLLTSDGTKKV
                     TLENVKPVTNSISAYSVEKDGISLVKKLQFTSTVTGSNTEITISTADFNAGDKVAVFY
                     LEELPKAKVIKIKEESTAPNYVIEADVMAKTADGEYMVLYMTIPNAKAQRSIELNLTA
                     ENPSGFNMTLDVLPDENKEYVVFAFVGDEDVSPVRMASMLGAELIDEKDVKSKK"
     gene            complement(29947..30723)
                     /locus_tag="KNP54_000274"
     CDS             complement(29947..30723)
                     /locus_tag="KNP54_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891209.1"
                     /translation="MLENYYITGLPIKLGETLGTVYQPTIEELIKFDMANLEIVNPFL
                     VLEKSYSQLCNEKIFELKCKYDAIPILDSSEEIELLSDKIKKSLSILYKTDIKNIEYM
                     NNIKIGILIKFDDKKKNAFISREDFGLVSDLILEMFCIDKKNLFKDDEDKWIENTGSE
                     REKQLIAHFKEKERKKREKEAYHLCDYINVVQNIDGYVPIDVILKMTYWQLINAYKTK
                     IQFKNYDESLGFAMSFKYQVEADKIKHWSKEIKIQTSTVK"
     gene            complement(30723..31217)
                     /locus_tag="KNP54_000275"
     CDS             complement(30723..31217)
                     /locus_tag="KNP54_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891210.1"
                     /translation="MAFPNKMISNIGATLMSNQDFAKFMIYNDESQKDILSMPDIKNP
                     VKELRNKKVFLNRRVEKVLKEADISVFIIMSEYRPCFEGSRTIKKTKIEIGVVCHDEC
                     QSTANGLRDVALVCCIVDIVTQNEEIAGIGKIKLENVYQMYNLNTDYNGFVITVSAES
                     FGDM"
     gene            complement(31232..32221)
                     /locus_tag="KNP54_000276"
     CDS             complement(31232..32221)
                     /locus_tag="KNP54_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891211.1"
                     /translation="MSYLSDTKKRIGLGCSTPKEKRILQLRLSFKKYLKETPTCIEVP
                     ITDIDEICITEDTKRAIVAINDITNNDKRALDEKNLLVESDLDVDVGCYLFYDNCYWL
                     TIFKEHKEMDTYKHFIIKRCNQFFNYKYKGQMYKIPIAVENLTLYSDGMADNKYTSIS
                     DTKRQLYFGSNPVTKTIDIDTRIMLTGKTVFRVTSINDFEYNGRETGADGLIKAICLQ
                     DALISKDDTINNIAWNDLSENESVIIPFSKIMGDGFINLGEENEYKIDHSQGVEWLLD
                     KQYGYCNIINQDEKKCVIQANTLAKYSGFEALLLAKDKDTNKTIDTKKITLRG"
     gene            complement(32223..32852)
                     /locus_tag="KNP54_000277"
     CDS             complement(32223..32852)
                     /locus_tag="KNP54_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891212.1"
                     /translation="MGTPLVKIYKKFLDGINDEEMLLLSNEIIEKMMYSYLEDAIVDF
                     NQCKKDLTIKYVDEKGGEIIPAAQLSYTSNYSNKNAEITLMGKDTKEEYELDKDYTIS
                     FEDEKFIISFVVETTEEIIFKYKYLGEIVSDLDLDEIKILSYGMQIHWLQPKINREEN
                     LKQMLTDSDYNAKSGANMLAKLQAREEQLRTRFNKYQQRYMLKNFEGWN"
     gene            complement(32867..33499)
                     /locus_tag="KNP54_000278"
     CDS             complement(32867..33499)
                     /locus_tag="KNP54_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891213.1"
                     /translation="MARAKKENISKTEVKVNTLEKDIKSTLNKKEARLNRLELQRKLK
                     QKKQEIDIEIKNISTWDVDYIDPREKQQIFSLSKVGSKDSTEFIDLDTLYRIVRRSPG
                     FFEEHRLIISDVDSLDVECTPMDIIDFLGLNSLYEYIRNPNEDYLEYFLSDKVDINSF
                     EKILNKNNVELTRRLAERAIDLHKKKKFDSGLKAKLLAKRIGMEDLYLFS"
     gene            complement(33553..34563)
                     /locus_tag="KNP54_000279"
     CDS             complement(33553..34563)
                     /locus_tag="KNP54_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891214.1"
                     /translation="MATAKTLKRIAHELYTDTFREYTDRDGNTITYRDAESAIKNKLK
                     EMMGGEKYNYYKFQENKWGFYNLISELISDDINRLNEEVFSPFCDFENFDLGDKKEFT
                     VENTNLFKVANIADGVNSTRRQRLLNKKVPTTAFKLSVAIYEEAERFITGRINWVVFV
                     NRVSDSYHYDIARRIAKTFEGAYSTINAKFQATGNSDKVLLELIAKVEGATGKKPIIY
                     GTPLALSNLEGVQTDLEKEEKRKYGFIQTFRGGYKVLSLPNAYDENAAEGKEWALDNK
                     AIYVIPDGEKIIKLGTEGDVLVIENTDEKERDDQQIEYFMAQKIHLGVVTAAKFGVYK
                     IQ"
     gene            complement(34651..35148)
                     /locus_tag="KNP54_000280"
     CDS             complement(34651..35148)
                     /locus_tag="KNP54_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891215.1"
                     /translation="MKKDKAIIQTDKVKNPDVLTGKYVVPSEDTNPINLENGAVINIG
                     ELEDTEYGRDTHKIYKVTNDTLDWGIVDDPATMYDERLDERDYEVSPGQICRCRRLKK
                     GDEVTISLLHIADKSIAVKDKLQLKSDSFQFEKLPTADAKTPVAEVLELWNYEGQDSV
                     TIKVL"
     gene            complement(35163..36596)
                     /locus_tag="KNP54_000281"
     CDS             complement(35163..36596)
                     /locus_tag="KNP54_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891216.1"
                     /translation="MKKIKILKLPCNLKHYSDKKKLEELNSNLLPVYIYVMHEGTNPN
                     GTKFYEEAIDKAEPTLKNVPILGYVKINEDGKYDFDGHNVLTQVVQTDEGFILEEYYE
                     ERIIGVIPETNKYEKVEIDGQKYVKCKGYIYKSYSNHAYDIIMDSDEIEISMEIDIND
                     YQLDDSDGFYNIKDYVYHGITCLGSDVKGAMGSNCCLTKFSRKINYKEEISKICSEIY
                     ALEHGEGEKNLPNKNQKLNKNSEGYALAVSNLSTEIRNKLKEYKVETENWYGEKVEVQ
                     AFYYNDLIPEENIAIVEDEINWGYYYGIPYIVNEDAVILDYENKKSYIQTWREKQEGE
                     IVQVFSRQEKLKKEIIEKFTEKQKEISNLKASLEPLQAFKEEKEFELFKSKVDDVAQK
                     FELAEDEIKDIKIKAYNKEITLDEYKKELGYIFALKTLSNKQSEKENFSINDDKNNTI
                     KIPISNNNDSFSEPEEISFIKKYSDKE"
     gene            complement(36603..36794)
                     /locus_tag="KNP54_000282"
     CDS             complement(36603..36794)
                     /locus_tag="KNP54_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891217.1"
                     /translation="MSKFIYAFSEDDKKLLMEKGYRFICENKLNNKTLYVFENKSKLI
                     NNFSNEEMKRFIFTSKIRF"
     gene            complement(36797..38275)
                     /locus_tag="KNP54_000283"
     CDS             complement(36797..38275)
                     /locus_tag="KNP54_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891218.1"
                     /translation="MGKKNNNKSKSKDNNSTQNQINMLNAQIGKYASVKESTTLATEM
                     YKLRSISRDKLRKALSNPYQISNTDILQDASMILKATSGTYRRVLNLISNMNTFDHIL
                     YPKDISRLKTKEKITKAYMNSASQLEKYNIKFTSAWITEKVLELGEVYLYKIEDNSGM
                     VLQQIPAKFCMITMIENNVMRYAINIKKLTDKNIISFPEEIKNIYKKYKSNLLTREEL
                     IDNTYFQLSDKAVAFNYDLDSVKGVPFFCFIFDDLMELEDMKDLKSTNAVIESIKLIH
                     QKIPFGKNDEPLVDLNLIPIYHNSTKANLPKGTAITTNPLELETHTLSDGKSKINDYV
                     KEAKEFIFDNAGINTALLNSDKINNESILNGIIADSLIPMRIQQMIENWVNFELNKDK
                     KANLFNMKFIGTTHFNKMNLSKQYREDMGYGGSKSLFIASTGFTPLQAINTLQAEKLM
                     GFDEFLIPQQTSHTQSSGRPDKSDIGTDNGNSTQAKGNGEND"
     gene            complement(38292..40040)
                     /locus_tag="KNP54_000284"
     CDS             complement(38292..40040)
                     /locus_tag="KNP54_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891219.1"
                     /translation="MRTKYEKRELSSNDSSRNLLESIGEYWGAFYLANPHRFCMDYFG
                     FNLHLFQQILIYMMMKSDQFVFIASRGLGKSWLLGVFCCVIAVLKPGTCVLIAAKRKK
                     QAKLLITSKILGDLYLKSDTLKREIKSFQVNAQEVSIDFWNGSRIEAVVSNDDARGYR
                     ANVLIVDEYRMVDEGTVNDVLVPFLTNPRQPGYLQNPKYRYMQEENKEIYLSSGWYSQ
                     HWSYKKFMETVKGMLSGEDMFACSIPFTCSLEHGLLTKKRILKEMKKESMSDASFMME
                     YCGVFYNESDDAFFKSSWVNPCRVLESMFYPPSDIEYLENKKKRDKKYHLNKIKGEIR
                     IIGADIALARGVKNDNSIYTLMRMLPNEGTYKRCVVHIEAYNGMEAEKQAIRLKQLFS
                     DFQADYMILDTQGIGTTVWSYIQKANYDSDRDEWYDAYTCFNEDNTVDKSLAKKSLPV
                     VYSMKAYADENHKMAMSLRDVLTNRTLELPISDIEAKEMILEKEMIKADEIDKKAELE
                     AKYIAPYLQTTALVNELINLEYSADGGKIKIKEKSGARKDRYSSLAYTNFLADYLEEK
                     EKRKNRNNQKTVMIYW"
     gene            complement(40030..40929)
                     /locus_tag="KNP54_000285"
     CDS             complement(40030..40929)
                     /locus_tag="KNP54_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891220.1"
                     /translation="MAISKTKCLNCGEEKYTDRYFWKSHSEIFTLNKRLPVCKECFRA
                     RFLLLNGCYNGELVKALKHICFNFDVYFDEKLAKELADKKNKDELIDEYMKIINRNSK
                     YKGKTSLDNLLKEIYTGNNNDKNIVINDEIKLKWGRGFDDYEYKILERKYKEYKEYYE
                     PESLTERKLFEEICIIELEKDKSREKGDMKAFNDLSKLVSSKMQDAEIKPSQKKKAGD
                     SQDDTFGMKMMIYEKNQPVKDRLKEYEDVDGFEAYVNKHMKKPLAVALGLATGKYSIN
                     DGDKDIKFKDDVRDILEGNKNED"
     gene            complement(41060..42259)
                     /locus_tag="KNP54_000286"
     CDS             complement(41060..42259)
                     /locus_tag="KNP54_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891221.1"
                     /translation="MEDILKKKEDESLVDYRIRIRLAKVNKEIDLDWGEIVELLGLEC
                     SPDHCRKVSYGLKEAFDYLNSKIQNNSTQEEIDKINEKILELKKIKVQLSDERSLVNK
                     KIREYSRIDNIIDLFNNKIDDISLHKPFLSDSSYKCYESSNQEAIMLISDIHYGLETI
                     NAFNRYNSKIFKIRIQYLKDKIIEYSKLHKVKRLHVMLLGDLISGYIHNSIRLENREN
                     IVEQIIEVSEILSEFIYELSKEIDKIIIYSVGGNHDRVLPKKDENLDKDNFTLLIDEY
                     IKLRIKNINNVIFQENIYDNDIIVAKICGNTCFGVHGDKDKMSTAIPKLTSLIKLIPD
                     YIFMAHLHNCKEDNYGESEICVNGSFSGTDSYAKNLRLSSHAMQKLMIFNESGRICTY
                     NINLSKL"
     gene            complement(42336..42524)
                     /locus_tag="KNP54_000287"
     CDS             complement(42336..42524)
                     /locus_tag="KNP54_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891222.1"
                     /translation="MKNNKGTVLEKCEIIKQENNTYKIIEHLKDGDHEVLLSDVLDKY
                     TGDTDLNITIRLSETIVQ"
     gene            complement(42894..43511)
                     /locus_tag="KNP54_000288"
     CDS             complement(42894..43511)
                     /locus_tag="KNP54_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891223.1"
                     /translation="MVKYNVHKALAEKKLLEDKIDRCINNFKIVGTKKGSDKNVYETK
                     TSVEDFNVEVSSKYQQIEDLIYNYNALDKAINISNAITNVQISNKNYTVLEAIKRKNS
                     IELDKSLLRQMVSNYDCMMSEVNRRNEEVQKNTDRMFEEKEKSKDGAELISFYKKQQE
                     WSLVDPLKVREKIEKLRDEIEEFEKEVDFALSTSNALTIIDVDLR"
     gene            complement(43567..43657)
                     /locus_tag="KNP54_000289"
     tRNA            complement(43567..43657)
                     /locus_tag="KNP54_000289"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43622..43624),aa:Ser,seq:gct)
     gene            complement(43666..43739)
                     /locus_tag="KNP54_000290"
     tRNA            complement(43666..43739)
                     /locus_tag="KNP54_000290"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43703..43705),aa:Ile,seq:tat)
     gene            complement(43758..44588)
                     /locus_tag="KNP54_000291"
     CDS             complement(43758..44588)
                     /locus_tag="KNP54_000291"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891224.1"
                     /translation="MNGEKLIENKELRDRNIDRVDVLEHVKEILTLANTDFSTVELVS
                     EYYEVDRDTIKKLIQRNRIELELDGLKLYKYNDIAEVLENTKKGLDVTFKIPPRGLIL
                     IPKRAILRIGMLLRDSEVAKEVRTRLLDIVHDAEEQTEIVIEEIRNEQNIKEDMLEAI
                     ISGDHNKLSVLQTELIGLKNKRISHLEDVITNSVTITESKAIINKCVRTIAVKKFNCM
                     FGKAWDEFYRFINYKLGINVRNRKGKGLARFSDEEILKMEKIAKSWLEENDIDFKLVI
                     "
     gene            complement(44876..45154)
                     /locus_tag="KNP54_000292"
     CDS             complement(44876..45154)
                     /locus_tag="KNP54_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBF0891225.1"
                     /translation="MKKVDFLKEVAEELGVSQIRVREILDVIEKKRNEVLQDGEELTL
                     MGVKYLTKIQKGKEGEITLKDGTKKPWKTEEKRVPKLKIAKSLKDAII"
     gene            complement(45288..46730)
                     /locus_tag="KNP54_000293"
     CDS             complement(45288..46730)
                     /locus_tag="KNP54_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891226.1"
                     /translation="MIYNNNNFYEEIDGKSAQDYIKNLDYSIDNSKDRIKYIEERLGV
                     KHTWFEESNRNYIDTFYNTLTKRNENIITRVKYQEKKQFNDKFWENIFEQTSDSPLDK
                     DGVYYVTIDGEEVVMDYNRFITWCGYNQINPIEYINVKNPFSNSNGTWEYTHHNTSKI
                     KLILNKDDSIYSTSNIAKTLEIMGSYILSVDDKPKETKIRIYNSKELFNRACQEEALL
                     NKIAPANGGNINSNTSNKDGFLEDNSFAFFQLPKNYKKIKDIKVKPKDIKKYPIIKTY
                     SDTYEWYKAKYKELGHKQLSKEELKLKRMVRKNLNALKNDMTDVKNSIERPIIWKAPL
                     ADAGSPEWDYLDMFDKSHVKELLRIQKGNDLQDDLTCIVMDLNNIISKIEFTTVQKDI
                     LNLYRKDKSLEFISNLMNITPQAINNQINKIVNKIIDAYEKNYEENYYYISVCKGKYK
                     KCSRCGKIKLLSRFDKNGKKGYRSNCKNCN"
     gene            complement(46733..46981)
                     /locus_tag="KNP54_000294"
     CDS             complement(46733..46981)
                     /locus_tag="KNP54_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891227.1"
                     /translation="MKEKKIELIYLEDLDESEKTGVHKNRYQILNEEYEQMIDTYTEM
                     SKRSSYDIVNERHKEDFKDELWDYDDTDYDDGLQGKEV"
     gene            complement(47159..48022)
                     /locus_tag="KNP54_000295"
     CDS             complement(47159..48022)
                     /locus_tag="KNP54_000295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891228.1"
                     /translation="MKRGEVLEIGKRKKSFSPEQRAIINNKKELPYHNFKLGGFVFCT
                     YVKNELLFNEVNISKANISRLIYLATYLNYNTGEENLLVRYSQFKEMIPIDRKNMREI
                     LNLKDRAFRNFLADVKKCELLYESNNKFYINPKYFTKGIPNFENKEYTRIYINTSRFL
                     FEHCTPRQHKQLSYIYQLIPYIHFESNILCLNPHETDISKIKKISLYKICQLLNISTI
                     KQDMNKFKKELLRFYIKVEDDKYYFFKYVIVEGNNKNTDYFIINPCVIWKGNNLNLAK
                     KTIDLCFFNCI"
     gene            complement(48294..48566)
                     /locus_tag="KNP54_000296"
     CDS             complement(48294..48566)
                     /locus_tag="KNP54_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891229.1"
                     /translation="MKKSSSFYLEEDIFGEIEKYQNDKNISSRNTALERIILEWKNLQ
                     EENKLLKQCLGNGVYRTNKKTNVTEEKKDIKRENPIIKNIFNNMPD"
     gene            complement(48579..49493)
                     /locus_tag="KNP54_000297"
     CDS             complement(48579..49493)
                     /locus_tag="KNP54_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBF0891230.1"
                     /translation="MEENYQVIGLDIGRGYVKGYSKYNGMVKECLFKSVFGDGRNIDF
                     EKYENPIYIDFESVSYFVGSLAEKESITPIRNSDDSKVSFTMRILVAAALNEIAVADE
                     VKLMMGVPYKSFRKTTLKEVVDTYKGKTFKVKDKIKGGHKEIKISDISIFREGDAALF
                     HTLEGKVNEDKAVGMVSIGFRSTEMSFFEKGFVFNDKLSDTLEAGNQDALTMVQKQLK
                     DRGIIRELNEIDSSNDYDELKKVAYIMASESTAQRISSKWKNIDEMDVYVSGGTALHM
                     TFDNRFKVSKDAQMATAKGLFEVGMEQF"
     gene            complement(49915..50103)
                     /locus_tag="KNP54_000298"
     CDS             complement(49915..50103)
                     /locus_tag="KNP54_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891231.1"
                     /translation="MESGLFVSRILCVVLSFPHFKKIADGFTDEIALYFPHKTNIYLK
                     IFLRFLLLNYILNKENIK"
     gene            50599..50757
                     /locus_tag="KNP54_000299"
     CDS             50599..50757
                     /locus_tag="KNP54_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891232.1"
                     /translation="MRITKGKIKELIELCHQLEKLFVQVFKSLEHILISLCSCIGWLL
                     ILIYIIKH"
     gene            51010..51201
                     /locus_tag="KNP54_000300"
     CDS             51010..51201
                     /locus_tag="KNP54_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891233.1"
                     /translation="MKLEKLIDIRKEKKYSQEDIARMLDISLRNYHRKEKGENQFTVS
                     ELEKICSYLDIESKELLDI"
     gene            complement(51415..51726)
                     /locus_tag="KNP54_000301"
     CDS             complement(51415..51726)
                     /locus_tag="KNP54_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891234.1"
                     /translation="MNRLKEVRKERGYNIQEIADKLNVAYNSVLRWENGNRKIDIDKL
                     VELSNIYNVSIDYILCKTDLKENIQLKEEEVNLLDNYRELDTKSKTIVQEQINTLKKL
                     L"
     gene            52455..52778
                     /locus_tag="KNP54_000302"
     CDS             52455..52778
                     /locus_tag="KNP54_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891235.1"
                     /translation="MDEKILELLQKMDTSINDIQGEIKWINTRLDSMDGRFDGIENQL
                     SDLKEGQEEIKKKLDLTYNQVARNMEGITEVGEKIDTLKNDMNFVEMATSKNWNEIAK
                     LKSIK"
     gene            52790..53023
                     /locus_tag="KNP54_000303"
     CDS             52790..53023
                     /locus_tag="KNP54_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891236.1"
                     /translation="MDEKTLELLREIQESIKILNDKLDEFDYTQDKIKSNVEGLLECF
                     SRIDFRIEDLENGQTSLYTKLDIVQNETAKSIK"
     gene            53118..53306
                     /locus_tag="KNP54_000304"
     CDS             53118..53306
                     /locus_tag="KNP54_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891237.1"
                     /translation="MYEQRKAKVIFNKGAGNSRGESYTNRVTIPTTWIKHMDITKLDR
                     EVLLTFDGNKIVIEKIDE"
     gene            53427..54140
                     /locus_tag="KNP54_000305"
     CDS             53427..54140
                     /locus_tag="KNP54_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBF0891238.1"
                     /translation="MLNIYITNLGKYNEGELIGEWAEFPVNEEELEEILDRIGINEEY
                     EEYFITDFETDIEGLEISEHSNIEQLNELAKELEELEEYEIEQLKALLGCGYIDFYDM
                     LEGDICRLSGNYTFIQLDDRSPLDDENLGRSYIEEICCGDLSCIENIAYYFDIEAFSR
                     DLRFDRDMIIENLYEEDIEYYENMTDIEFAENYIERLGDIEELGQETLERYFNYELYG
                     TDLRYENICIASNYLAIVS"
     gene            54208..54348
                     /locus_tag="KNP54_000306"
     CDS             54208..54348
                     /locus_tag="KNP54_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891239.1"
                     /translation="MKKLIIKIKSLFKKDLDSSYWSTTESIILKCGNSNQLELLEQAN
                     KL"
     gene            54628..55323
                     /locus_tag="KNP54_000307"
     CDS             54628..55323
                     /locus_tag="KNP54_000307"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891240.1"
                     /translation="MNKIIVFYDIEGHPGFQVLVRNVKKYTRQNIIFELVEDYIKNNI
                     GEIDLKDEKIYSSVSWKVWTISDVAIYNTLFDLRLDYNKLIESEEEDTDNKECVKELF
                     CMGKGCKWMETVLLLRQNKIDSSQYNILTINNYTYVKTWAEQCKKILLANNYSKVFKF
                     NEIMKDCDNNLIGDICFKYNNKEYKHKFTFNIKKDKLVNIDCEYKIPFLRYVFNDIEK
                     FLTRYSENISNLK"
     gene            55463..55648
                     /locus_tag="KNP54_000308"
     CDS             55463..55648
                     /locus_tag="KNP54_000308"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891241.1"
                     /translation="MQELCSMGLTYPFDFGRGKGKYQTNIDEETIYKRAKENTKIQEY
                     SKKYLNYIAKIKKSISK"
     gene            55682..55978
                     /locus_tag="KNP54_000309"
     CDS             55682..55978
                     /locus_tag="KNP54_000309"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891242.1"
                     /translation="MKKIINGYSIYKDGTWCEVIKEGKFIFAGSVNEKLSYEDIYIAL
                     TAKLEFRLHGKLLLSYSLYGTFQGEKQSTLELLAYENNCNINDIEVKQVVENIQ"
     gene            56115..56660
                     /locus_tag="KNP54_000310"
     CDS             56115..56660
                     /locus_tag="KNP54_000310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891243.1"
                     /translation="MKKIANLNKEELKIIWEKNSQLREDVRKACEDNDMYWIDEILCH
                     LNKSLDDWSIGFYNDNYIKIEDNHKFLLELKSVCEKFSFLSEEEQRPLEYAISLIDKL
                     HCMDFENKRFNMLENKINNMVKKLEEKVIEEFNKMTEPLDKEYLLENFIEFYVEAYLN
                     DNEFYIDNEYVLYEKIIKSYA"
     gene            56686..56949
                     /locus_tag="KNP54_000311"
     CDS             56686..56949
                     /locus_tag="KNP54_000311"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891244.1"
                     /translation="MLANQIKGIKTSLETSSLRELKGYIKDLRKALSGYKYKNKIDEI
                     TEYQIDKLCYKIDNTDIFDLKYKEIEKYIDSLILILDFIFMEM"
     gene            56987..57571
                     /locus_tag="KNP54_000312"
     CDS             56987..57571
                     /locus_tag="KNP54_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891245.1"
                     /translation="MNEYILISYTKGEGTCDHCGRTIKNIATIKNNVTGEVFHVGLTC
                     VEKIMKLNVTFYKALSREIKKHYKCMEYYSKGLDIETNLNKIVKNNTKYKEGSYAYKS
                     NEQMLEDAIAEVAWSLARMIDSCMRMNKLSKSGLIDIDILNSLFIKYKEYMSKFDENY
                     NKNKYKYKSCYTMKPLKVILDENEDLKELYKSMQ"
     gene            57875..58396
                     /locus_tag="KNP54_000313"
     CDS             57875..58396
                     /locus_tag="KNP54_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891246.1"
                     /translation="MKFKNIVMGMLLGLIIVGVSGVTKVKAAELDNFYIESTDRVIEV
                     LEDESIVLYDTKEQVYNFYPICMGDWNYSFKNKKDLDSAVATYKELSSNINHLSNIYV
                     VNKLNDNGNIKVFLNDGSSIVYIKQDNKYYFYPSCMGDWYLTLDSKIYLTNCINTYIE
                     YYYSLSTGGGTNE"
     gene            58389..58619
                     /locus_tag="KNP54_000314"
     CDS             58389..58619
                     /locus_tag="KNP54_000314"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891247.1"
                     /translation="MNNNDKLSILNQLEYIENDIDARNEMIEKFKDLLVKYPKSRDIR
                     RYIKQQTQFLNGIRYIYDNLDILKNMINNDKK"
     gene            58790..59599
                     /locus_tag="KNP54_000315"
     CDS             58790..59599
                     /locus_tag="KNP54_000315"
                     /inference="COORDINATES: protein motif:HMM:NF022027.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBF0891248.1"
                     /translation="MNKLKVKGKQKFMNLEIPVIEGGFGEDKKCMTDKTISEIHNQPN
                     FKIRERIKDNIKRFKEDIDYIDLKVIRDTDDNLELLQTLGYSKMQISKADNIFLLSER
                     GYSKLIKIMDTDLAWEIHDKIMDEYFSMRKKLNDPFENLSPELKVIIKLEQRQAELES
                     GQHELEEKVNVLYDFSTIDYNQQETIRSLVNRMVIQVYQCLNFSAYEDAKLRKRVYFS
                     LWKDYRKKFGVNSYKNTAKKNYDNAIKFIENWEPNYDLSNEIYMFQKVENI"
     gene            59877..60593
                     /locus_tag="KNP54_000316"
     CDS             59877..60593
                     /locus_tag="KNP54_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBF0891249.1"
                     /translation="MNILIENKFIEKLKYTKNIPNSLYKDLRHNFLFHSNKIEGSTFT
                     SESLQDLIEHNIVKGDHTLDDVITTVNSSYVFETVIDTLGEYLTEKYIKDLHGQLMYN
                     SNIHNMGLSGIYKKIPNRIIGTNSVLAQPFEVEPKMLELIEWYNNLKDITLKDLAEFH
                     YRFEIIHPFQDGNGRIGRFILLKQILENNLKLIIISSDTVDDYRQALKGCHNEYYKPL
                     EQYFESLDDYKEKNKDLWSF"
     gene            complement(60835..61134)
                     /locus_tag="KNP54_000317"
     CDS             complement(60835..61134)
                     /locus_tag="KNP54_000317"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891250.1"
                     /translation="MVIKVNFGGNYSPDYIYVPNEISLKKYEIRNEFHIWIDNTEDEH
                     PFWCYENGVQIGLHYRGDAIVYWLNNYILKNANDKARLIESFSNKKLDYDLIINL"
     gene            complement(61330..61512)
                     /locus_tag="KNP54_000318"
     CDS             complement(61330..61512)
                     /locus_tag="KNP54_000318"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891251.1"
                     /translation="MLKTLFILLAVFVIIKLSILIFKDALKFLNMFESKNESFIGWLF
                     LCILALVIYNLIDIIL"
     gene            61708..62280
                     /locus_tag="KNP54_000319"
     CDS             61708..62280
                     /locus_tag="KNP54_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBF0891252.1"
                     /translation="MTWNDLKNNDITYIVEYINNKLNNSKSLTKVAIGLGVSESSIRK
                     YLTKRGYKRINDEYVFIGDNSMTKVVNNRQQSNNDNTFNMTIEDDNNHNIVIDNQFKN
                     NIVSLAKDYDKIQDVLNWFENKEDTNVIEVVQDGIKIDLHSKDAIRTTVRLNKDAWNL
                     FDEFCGKFREFNKSDLMSMALLEYIKKYDK"
     gene            62413..63339
                     /locus_tag="KNP54_000320"
     CDS             62413..63339
                     /locus_tag="KNP54_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891253.1"
                     /translation="MNYNLKNENVLSELLQNEDEKTRIGILKVYKVLIFWFAKEGKLV
                     EEENDYIVEIVGNDKEEIVRDMSQNKTYNAIMAIIFKINKIFKTLNYDIHFSKPKNLV
                     AEFDLSKYLTQDEVLQVCSKLTNAQDKFIIYAAFCGLIGKDAEDLRGIKIKDIDLEKR
                     LIKLKDTEFKLDKFLFDFTKDTLEQKEYKQYLEQDSNAAEFYLFNSNSEYLIKTKPDA
                     RYGNGLKEMGYSTIRKRLLIINDYLDNKVQLNFTNLKISGIMHQMHLNEKKYTQSGYW
                     TNKSLKEFKEDNNLNFKIQEVLSIYKQKYIKE"
     gene            63344..64912
                     /locus_tag="KNP54_000321"
     CDS             63344..64912
                     /locus_tag="KNP54_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891254.1"
                     /translation="MSKDVKENISNEQKDLNKINLIYHIIYDNDRFKMITRKYFEIFR
                     LKGMSAEEISLKFEEFLYSLISDKFKKINTVNDVKKLRNQENSSSLKLKKRWSDMTLD
                     SLSEDTKSSRKKSSKYLKKELEIVESEYLKNGRIISAGVKNPKELKEQRKDFLDEWKS
                     SSSYNICDYPYLQELSTSKINSAFIHDILMCITEVLKDDYDFDINKIAIKTPPHISPG
                     IFLPFTKGKRYSHLNVKKNENEYMSDDYSAKNLSGKQMNFFYKFSIGQDENIENLKLE
                     LINPDTEKRALPKIYLDKQDLEIIRFVYTYSHMNSFSFYLGDLVKYLGLSDGKKNYIN
                     IKNRLLKLPYYTFYSNQTNDKGELKYEISFNLFSSTTIVNDENNNNRELVKITKSFIE
                     EVERVNTDIMYRNELEKLQLTQSINLAYFLEGRRSFLISCGEDIKNKSFRYDIEDLKF
                     DVHLNKSKTVKQNMEYLELGFNEIKENQFIIKDYKRGNSYFDVYFYEDFEKRKRLINN
                     TILSLPDYMIENKS"
     gene            65386..65652
                     /locus_tag="KNP54_000322"
     CDS             65386..65652
                     /locus_tag="KNP54_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain containing protein"
                     /protein_id="HBF0891255.1"
                     /translation="MSLKYKDKEFVLVEKKNINELDNSNIKYIDLKDKQYYVVTQGKK
                     PKRFNLEDIKNIKKDLDNGISLRKCATKWNCSTRTIQDIKNNIY"
     gene            65728..66906
                     /locus_tag="KNP54_000323"
     CDS             65728..66906
                     /locus_tag="KNP54_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891256.1"
                     /translation="MQELKPVARISKSKLKDILDVFKTSIRKVEKIDYSACNSCAIKN
                     NPSFDSHKLNEFCSNCPKLKTISEFSYVTEKETELGTIEIVTNESKCMALSKSAIKQY
                     LAYHFIVSNKNYVRKAVSFQNIADICNVSIVTARHNHNVLLRVGLVYSTEIKRGKFDI
                     VIDEEYKNHLKKEDGGKGYLTMSLDTLNHLLSFENVNELKLEIKKLIWADAKGSKLGK
                     RIRFKKDNLISILPEYIKKSNKRTEAFLRSSKTLFDVSNDTIDTKRYETKETISEKYT
                     EPIRIQISKFFDNTGCSLSSNYSKVLSQINLDRYNLFEEDLRSKLDMEKDIIINDLVG
                     LSVQYGVTRVLAALDYMFNKYTVDEEDINYNEIRNPGAFIRTLIVQSINKNGSLAIAI
                     "
     gene            67515..69275
                     /locus_tag="KNP54_000324"
     CDS             67515..69275
                     /locus_tag="KNP54_000324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891257.1"
                     /translation="MDRFEVLKYLKFNVWHSEWPLELLKGAITKDNATGNLLLQLKMC
                     NISDKEIKSAYFTIECFNDAGDLIDNNLKYVYQDINIKPHECLGDDIAIKINDNKTRA
                     INIILEQVVFSDDKVHKYEREEGLIIPKLDKIELLNIELLEELKKDYEEYDFQYEIKY
                     MPNIIEKKAWSCCCGKINKLEKDKCDNCKRSKILQIKKINKNYLESIYKKSLKKKKEI
                     EIKLEKDNRHKLKNINKNNRRTSILLISILLIFIIFIGKNIINKHAFLDEIKYKNEYS
                     KKISVEKDNVYMLKNNGKVTHRKVNGESSSIPGWENIISIASYDNSIIGIKKDGTVVS
                     KGLGNSDSDNISKWRDIIDIECDSGTFIGLKKDGTVVATGNNDYGQCNVNNWFDVVSI
                     EITKSTIEYMKNTTVIGIKKDGKVLLTGYDSLNHRKETDKWRDISKIKCGSYGIFGIK
                     NNGTVVVSGSAYDIKNWKDIVDIHIGLCGIVGIKRDGTIISTDEKFNEIIKNWKDIIS
                     AEIIDNHEGISIVGINSNGDILTSSRGQNLDNIKRLEDVEYINFDDSIDNFLVGIRKD
                     NVIFIRGINNTINEEYNEEI"
     gene            69309..69665
                     /locus_tag="KNP54_000325"
     CDS             69309..69665
                     /locus_tag="KNP54_000325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891258.1"
                     /translation="MKNYIARCLSNMGVLLAGIQVLAGIIIMCQKVEVPYDYLSDTYE
                     QYSPIMIGIGAGVIVSGIVICLVLKGLAELVENSADQTQYQKEILMLLKNNNVNEKIN
                     EVKIEQQFTNEELPKL"
     gene            69874..70587
                     /locus_tag="KNP54_000326"
     CDS             69874..70587
                     /locus_tag="KNP54_000326"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012301.1,HMM:NF016296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891259.1"
                     /translation="MIITICENDDMQRDIIYDFVKIFLTKIKVKHYDILMFKNGEELL
                     EEYPNKVDLILMDINLGGRNGFDISKDIRKFDKDARIIFVTVSEKYAIKCYEINAFRY
                     MIKPIYYKEFEKYMLDFAIDWRKREAIITIKRKKQIIKIEEHNILFVEIVNRKLRVVT
                     KNEEHIINDKMDMFEEKLKEDIFFRCHKSYLINLLEVTNFNYNFVYLTSEKIKIKVAP
                     KKTKKLKEKLANFFREIIW"
     gene            complement(71051..71404)
                     /locus_tag="KNP54_000327"
     CDS             complement(71051..71404)
                     /locus_tag="KNP54_000327"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891260.1"
                     /translation="MNENLKELRIKLGLSQKEFAEKLLVSDATISRLEKGERKLTDRF
                     IFQICEVFNVNEDWLRNGNGEMFKNIDDIELAAMMGKTFSSNDEFLKKVFLTFAELTD
                     DEREVIQKVIDKLSK"
     gene            71584..71754
                     /locus_tag="KNP54_000328"
     CDS             71584..71754
                     /locus_tag="KNP54_000328"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891261.1"
                     /translation="MYNNNDKKLINLFESFKKIDYTEQSLVYFLSLSFIVNRKCHKDA
                     NLYSRRGECNYE"
     gene            71747..72553
                     /locus_tag="KNP54_000329"
     CDS             71747..72553
                     /locus_tag="KNP54_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBF0891262.1"
                     /translation="MNNLNIKGKQKFMDLEIPIIEGGFGEGKKCITDKTISEIHNMEI
                     KHVRELINRNIRRFINAIDFIDLKVVVDNDYNLEVLELLSYRKMQISKANNIYLLSER
                     GYSKLIKIMDTDLAWEIHDKIMDEYFNMREQLIDSYMIQDSIERAKRWIEEEKERLLL
                     KETIQVQQPKVEYHDKVLNPDKLVTTTDIAKDLGMTAQALNKLLHLNRIIYPERINGR
                     IKCWKPYKNYLWLIPEYADFKITEHDTQLKWTEIGRKWLIEFVENIKKIS"
     gene            72617..72841
                     /locus_tag="KNP54_000330"
     CDS             72617..72841
                     /locus_tag="KNP54_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891263.1"
                     /translation="MIKQILNKRGSLLNLASEYLTEQDYLKFQGWYTHRYSKLDAYDA
                     SINEYLNYKNDKKLITYVFNLKFQEALIEI"
     gene            72865..73401
                     /locus_tag="KNP54_000331"
     CDS             72865..73401
                     /locus_tag="KNP54_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891264.1"
                     /translation="MNYNYVTKIDLKYGNTQFGFEKYSDALDKYRELKEEFKYVPCII
                     KLHSYVAHQDLYVKEIKADGFEKKYLDIKNLIKLFKEHKQNISDELSLCDKKKEEVLH
                     VIEEMNLDTASLNDKIDTIKELKNTLVKRRLVKYELNKYFAFCNTLYEIEEELKKYES
                     KYKQKENQGKSRFKKNKK"
     gene            73410..73550
                     /locus_tag="KNP54_000332"
     CDS             73410..73550
                     /locus_tag="KNP54_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891265.1"
                     /translation="MEEYHFNLIKKLCAERKIHKGWFRNIEKCGCGGKCNKKNCKMLE
                     KL"
     gene            73561..73794
                     /locus_tag="KNP54_000333"
     CDS             73561..73794
                     /locus_tag="KNP54_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891266.1"
                     /translation="MENQIELTEKDIENTLSALNIIKYICIKSKHCKNCPLGYMKNLD
                     EHNCMLYELIDKGLLPCDWSVKKVTRLLDTTEE"
     gene            73813..74226
                     /locus_tag="KNP54_000334"
     CDS             73813..74226
                     /locus_tag="KNP54_000334"
                     /inference="COORDINATES: protein motif:HMM:NF021182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891267.1"
                     /translation="MELDFRIWNGFRMIHGEELRLLTEEMFIKSGYSEQYYNDICIPR
                     VEDLKIMQYIGLKNCFEKKIFQYDIVKFIFDGVWKVCLVNLSLPKGATVTFESIGGKY
                     TFNLSEIFSKDRKLEIIGNFYENKDVIKKYNLSIE"
     gene            74236..74430
                     /locus_tag="KNP54_000335"
     CDS             74236..74430
                     /locus_tag="KNP54_000335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891268.1"
                     /translation="MDEMIIRVKMGEPLPTLGKIIKCTTCLTNEEKCFKVNKICKLSW
                     INDRNSEGLIVECKGKYIKY"
     gene            74637..75191
                     /locus_tag="KNP54_000336"
     CDS             74637..75191
                     /locus_tag="KNP54_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HBF0891269.1"
                     /translation="MSKKDKLSIFISLILRHKPETIGIKLDDYGYADVNELIEKINNT
                     GRNINIEILEQIVKEDNKQRYSFNDDRSKIRANQGHSINVEVELKELEPPKCLYHGTA
                     TRFLENIKKEGIIRQSRLYVHLSNDIDTAVKVGKRHGVPVVLKINTGKMYENGYKFYL
                     SENNIWLCKYIPFEYVEKISRVVK"
     gene            75218..75544
                     /locus_tag="KNP54_000337"
     CDS             75218..75544
                     /locus_tag="KNP54_000337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891270.1"
                     /translation="MDFNFRKICEKDELTDDFIIKICQLSHEEFGGTIYVPCNIHPCG
                     WDELEVPNPKDLDSDKLMEEFLLEYKFECENISSNIYDSDHPFIGKTLREILMIVDCR
                     FIIGVI"
     gene            75559..76335
                     /locus_tag="KNP54_000338"
     CDS             75559..76335
                     /locus_tag="KNP54_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891271.1"
                     /translation="MENIELTPRDYFEDIKNKKQKNTNENLDIVYENSLILLNKYIVT
                     GQKKGAKKLMFLLECIEKERNVIELGIDTFVYKEDIEKYIDDISKNTVKIIELENYER
                     EIPDEIVEIIEKTKDIFDKMYVLFTDYTGKITKEISKERRDKDPILFGVFSDEKSRAI
                     VDRFYYLGDWEDEYCDLTLEKMINDYKKKGRQDILKHIITPKSLDELKKELDSLEKNN
                     DTYKQVANIKPLPTTKNSSVEPPKLNIFKKIKNRVFKNEK"
     gene            76325..76726
                     /locus_tag="KNP54_000339"
     CDS             76325..76726
                     /locus_tag="KNP54_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891272.1"
                     /translation="MKSNVDLTENRDFRDVRGRGINILGIEDAPNRMLSFSDFGIGRL
                     YGKNLEFEFNKNEVFLTGNANDREEKKFLILCEENKVCVRCGDELREGWDKVSIELCN
                     ECYEMLDVEYKNKKIIRELFFRDRDVNIELL"
     gene            76915..77235
                     /locus_tag="KNP54_000340"
     CDS             76915..77235
                     /locus_tag="KNP54_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891273.1"
                     /translation="MFIKSFRCIFRHKFSRIKDCQLITTRSQQYTCKIWMCKYCGQIV
                     AGSTPVYHPNMKVNEYCVKCEFSACANNYEGYCNSKDKEIEFKSICLKGNKEILQCKN
                     FDLE"
     gene            77266..77451
                     /locus_tag="KNP54_000341"
     CDS             77266..77451
                     /locus_tag="KNP54_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891274.1"
                     /translation="MKINVHVKTNKIGSDCELEFEIDDDDLKDMSDEEREGYIDKIAW
                     DYVFENFIDWNWYEVED"
     gene            77506..77907
                     /locus_tag="KNP54_000342"
     CDS             77506..77907
                     /locus_tag="KNP54_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase"
                     /protein_id="HBF0891275.1"
                     /translation="MKELLEVKKIFDSLASTSSRKEKERILEKYKNNRMFVECLQFLL
                     DSNILTGISKNKICKNLNNTGHNELENIYDMLDYLIKNNTGRNIDVKTIQVFASKDEK
                     LKDFIFNLATKSIKLGITYKTVDKIMPGLII"
     gene            78009..78512
                     /locus_tag="KNP54_000343"
     CDS             78009..78512
                     /locus_tag="KNP54_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891276.1"
                     /translation="MTDKIIIASVDGEEMIFRTEMKKLEKGDSLIVSVNGVKRLALFI
                     RYISTCEEYIEDIAFQKVDEILYENTIAKEKERVKKVFKDKCMKNYKPIVNTEIDSYL
                     RECGFNCDGRQFFKSIDNTQILISRDCDKDVLTVSKGLTITKTDITNKNLITVIKIIN
                     NSLLIVR"
     gene            78572..80797
                     /locus_tag="KNP54_000344"
     CDS             78572..80797
                     /locus_tag="KNP54_000344"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBF0891277.1"
                     /translation="MKNVIKRDGRIVPFDEKKIINAIEKSFLSLRNKGKSEVFDRELA
                     TLIAKKIKNKPCEKMHIEDIQDIIEFSLMASKKKDVAKEYITYREKRNIARGRKTYND
                     YMSIVNTESNDITKENANMNADTPAGMMMKFASEATKTFTDHVLLSEEAKEAMMDNYI
                     HIHDKDYYPTKSLTCIQHPLDKIFNNGFRAGHGSSRPTKRIETSSILGCISLETVQNE
                     MHGGQAIPAFDFYNAPSVRKTFIEEIKNIEIKDDIDLSHLYNIEIEDYIIKDLKELDS
                     EKRNVQHAINRTVWRVHQSMESFIHNMNTIHSRGGNQVVFSSINYGTDTSAEGRCIIR
                     EILKSTYEGVGNGETPIFPIQIWKVKEGVNYNPTDRNYDLYELACKVSAKRFFPNFLN
                     LDATFNKHVKWKMCDPNRYIYEVATMGCRTRVFEDLHGEKTSIGRGNLSFTTLNLVKM
                     ALEAKEKYPNNEANRVAEFIFLLDKYSDVVARQLYDRYLFQCTAKAKQFPLLMSGLWK
                     NSENLNPNDDVSEVLKHGTLGVGFIGLAECLIALIGEHHGESEKAQKLGLEIISLLKS
                     KVEKYKKKYNLNYSVLGTPAEGLSGKFTQKDKKIFGEIKNITDKDYYTNSSHVPVWYN
                     CNVEHKAKIEAPYHELEGGGHIFYVELDGDATHNPKAIMKVVDLMKKYNMGYGSVNHT
                     RSRCMNCGFENADSELKECPKCGSNSINIIQRITGYLVGTTDSWNNAKLAELKDRVTH
                     G"
     gene            80790..81287
                     /gene="nrdG"
                     /locus_tag="KNP54_000345"
     CDS             80790..81287
                     /gene="nrdG"
                     /locus_tag="KNP54_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBF0891278.1"
                     /translation="MDKDYIYILDIKHDTIVDGEGFRTSIYCSGCNHMCRGCHNPQSW
                     DIKNGTLTKVLDIYKEIISNKFSDVTFSGGDPLLQLQGFVHLAKLIKKNTNKTIWCYT
                     GFKFEELITDNEKLELLKLIDVLVDGKFEEDKKSLELIFKGSSNQRIIDVQKTLYEKQ
                     IVLYE"
     gene            81488..81895
                     /locus_tag="KNP54_000346"
     CDS             81488..81895
                     /locus_tag="KNP54_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891279.1"
                     /translation="MYFETDIIKNKNTVNKIIKYCGGNTEKLKDWLKEIENKSISSLE
                     ELKEYPLKRNYKFVFSKEEAPNLDKLIKMKLRDNCLEKCEICSLENLLSMLNDEILDL
                     NKEDISYEDNIEWIENCKEELIKLKVGSICIDW"
     gene            81916..82227
                     /locus_tag="KNP54_000347"
                     /pseudo
     CDS             81916..82227
                     /locus_tag="KNP54_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900673.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            82318..82668
                     /gene="tnpA"
                     /locus_tag="KNP54_000348"
                     /pseudo
     CDS             82318..82668
                     /gene="tnpA"
                     /locus_tag="KNP54_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378761.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            82686..84125
                     /locus_tag="KNP54_000349"
     CDS             82686..84125
                     /locus_tag="KNP54_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015978935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBF0891280.1"
                     /translation="MSNYILTLQLKTEKFQEDIICNAFDKYRKVYNSCLSELFKRYNH
                     MIESKEHQANCKYKGKDRNKIFSEINKKYNLTEYSLHKFVKFIGKYYKLHSAITQKIA
                     TRCFNAFNKYIYHQAKRVNYIRYNELTSIEGKQNSTGISYKDGIIKFNKMTIPVIIKN
                     NDNYAQRAIQDKIKYCRILKKEIKGKIKWYVQLVLEGIPPKKTTNQGKIKGQIGLGNV
                     GIDIGTQTIAISSKCDVKLLELAPNVNNIDRQIKLIQRKMDRSKRATNLNKFNDNGTI
                     KQGNRDKWIFSNHYLKLKRLRKELYRKQAEIRKQDHYILINKLLNLGNKFYVETMSYK
                     RLQTRVKDTTINEKTGRINKKKRFGKSLANKAPSMFLTMLDNKLKYNNERLYKIDTAK
                     CRASQYNHFSDEYNKKELKDRWNNGMDIQRDCYSAFLIMNVNEDLKSINRELCVKTYD
                     NFKILHDKEINRLKKLKLNGYKLISSMGI"
     gene            84326..84550
                     /locus_tag="KNP54_000350"
     CDS             84326..84550
                     /locus_tag="KNP54_000350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891281.1"
                     /translation="MVIYKNKKKDIIRDESMYDYGMSLSSIMKVILNHQEDIEKLKEE
                     EVAEFIKNKLENEHDCDELKIISEVFNEIY"
     gene            84537..84647
                     /locus_tag="KNP54_000351"
     CDS             84537..84647
                     /locus_tag="KNP54_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBF0891282.1"
                     /translation="MKYIKHVDNGVMRAIGIDNYKPLLNIIKEKVNLESN"
     gene            84676..85143
                     /locus_tag="KNP54_000352"
     CDS             84676..85143
                     /locus_tag="KNP54_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891283.1"
                     /translation="MGLDLGFYSVKTKVTDLDIYLNKTRGEKYKELNNDEEEFYKFEE
                     LLDIDISLEDWSVIRMIYKAKWEKGYESYEDEAILITKEDLEDYIIPFLKQKDINSKI
                     YNKDKEYYYKNDKKVTVDDRYTQEFWDLVLKEFQKMLNIIDFEKHSLIIMYWY"
     gene            85179..85559
                     /locus_tag="KNP54_000353"
     CDS             85179..85559
                     /locus_tag="KNP54_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase"
                     /protein_id="HBF0891284.1"
                     /translation="MKKMYIAINSDLNMSPGKVGAQVAHAVYDYLYNKILDTVSCSYE
                     TEIIAHELIDLKCDLTSFKNNGDTICILKAKEAQLLKFKEKGYLTIVDRGLTEIPKNS
                     ITCVNLGIFNEDEIPSTIKRLRLY"
     gene            85575..85730
                     /locus_tag="KNP54_000354"
     CDS             85575..85730
                     /locus_tag="KNP54_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891285.1"
                     /translation="MYSKGDVVKVWCYQCERIEFQEFVGYFNSYFDNYKLKKRWKCSK
                     CDVINNF"
     gene            85757..86203
                     /locus_tag="KNP54_000355"
     CDS             85757..86203
                     /locus_tag="KNP54_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891286.1"
                     /translation="MKIKKIILGLDNLENVELGIGDVGGFYLDNIHEIIGGFALSYIG
                     KCKKADYLHIQIHKRVDEIQRLHDYKDITNVKIEYEDGSVEDIYVPYKQEGDFLGLDN
                     LYQTSFISKQGYLHIVISKDKTVEEVFNEEFEDDEGVEFSFNMYGI"
     gene            86496..86645
                     /locus_tag="KNP54_000356"
     CDS             86496..86645
                     /locus_tag="KNP54_000356"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891287.1"
                     /translation="MEEYIINLIKDKIKEEYGENILPEILMEKFIKLERKGSVTVDVR
                     DLIEG"
     gene            86689..87942
                     /locus_tag="KNP54_000357"
     CDS             86689..87942
                     /locus_tag="KNP54_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HBF0891288.1"
                     /translation="MEVQGKYNKAKIFTENVDSITIGQIINLCNQKEFKESSIRIMPD
                     CHAGKGCTIGTTMTISDKVVPNLVGVDIGCGMATIPLEKYINNINYTKLDKIIRDYIP
                     HGFKIHNKSREKLLKNLFNIDINNLRCEVNKNRAYMSLGTLGGGNHFIEVDKSEKGQM
                     YLTVHTGSRNLGKQIADYYQDKAIKYCIEKYKKSYDDAKEFLISTLKKDNKEHLINKY
                     LKDLSDRKLNKPHDDLCYLENDLMEDYLHDMSIAQKYAAANRMVIIADILFKYNSLEV
                     NYDHFIRDIKCDVIECIHNYIDMDSKILRKGAISANKDETVIIPVNMRDGIILGKGKG
                     NSEWNYSAPHGAGRILSRGKAKEKISLDEFEESMKEIFTTCVGQSTLDEAPQAYKPIE
                     DILNNIGDTIEIMEVLKPIYNFKSN"
     gene            87984..88886
                     /locus_tag="KNP54_000358"
     CDS             87984..88886
                     /locus_tag="KNP54_000358"
                     /inference="COORDINATES: protein motif:HMM:NF014342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891289.1"
                     /translation="MIKLITHNDLDGVSCCIIAKYILREQIDVNYCNYKNINDVVLDT
                     LKNHDKYEQILITDISVNEDVAKKLDRIKNKVQLLDHHPTALFLNNYDWANVEIECNK
                     GKTCGTQMLFNYLQRYYDDTSESTLKYFIELVRRYDTWEWKDKYNDLDAKYLNDLMYI
                     MGIEDFIMDMLTKIDSDEMCLFDKLSLKLLEIKQKEIDRYVEKKDENIMVKEILGYNA
                     GIVFAENHISELGNKLSELHPELDFIVIINREIISYRTIKDNINLSEIAKVFGGGGNP
                     KASGSQIDESCIDNYIKDIFNIKS"
     gene            88994..89272
                     /locus_tag="KNP54_000359"
     CDS             88994..89272
                     /locus_tag="KNP54_000359"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891290.1"
                     /translation="MMIDKFNYELYNEFPHLSPIIELYNLNIEYIREVVSILINTDMT
                     FQRFKYSKSRVECSMKAYIISPNSKLSVVFAYDCELNGIDLDNLKAII"
     gene            89319..89729
                     /locus_tag="KNP54_000360"
     CDS             89319..89729
                     /locus_tag="KNP54_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891291.1"
                     /translation="MCKFCESIIDNTKDILLTSRSRLLEDNTCEIIAEDNCNNCYDGC
                     YEYFKLNGYKIRGNTYVNVDYYKKIRKIIIAPCSESVHINYCPYCGKQVSKDIKDFNC
                     IPEHIVDVRYKNGDVYDYDMEKSVQEVMDNANNN"
     gene            89760..89933
                     /locus_tag="KNP54_000361"
     CDS             89760..89933
                     /locus_tag="KNP54_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891292.1"
                     /translation="MNLWSKIEEPVMRAVSGIVFNIWGNVCFSIYYIEENKQIELEIY
                     DRPYRYEGKKNSC"
     gene            90043..90186
                     /locus_tag="KNP54_000362"
     CDS             90043..90186
                     /locus_tag="KNP54_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891293.1"
                     /translation="MNKGIKNYITAVNYLLDNLEYMMEDDEFNNEKLQKRIDVIRKFE
                     REL"
     gene            90188..90493
                     /locus_tag="KNP54_000363"
     CDS             90188..90493
                     /locus_tag="KNP54_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891294.1"
                     /translation="MGKIKNGEIDTEDYRLFKNIQKEKDRVYSKYINEEYIMEEFINY
                     LRLEDKDYTTEILERYARYIDENLDNRCPYCVYNICSEHDNCFDGILENLKEKIKIK"
     gene            90651..90851
                     /locus_tag="KNP54_000364"
     CDS             90651..90851
                     /locus_tag="KNP54_000364"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891295.1"
                     /translation="MIKERFKAKDSFNMDEFTKIWLMDFKEDFDLSLKKMIENTIKKS
                     IKDTYEETERAITNIENLINKL"
     gene            91056..91340
                     /locus_tag="KNP54_000365"
     CDS             91056..91340
                     /locus_tag="KNP54_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5052 family protein"
                     /protein_id="HBF0891296.1"
                     /translation="MKKFLLTGLLGTMLIAMSGCTGIQSSMKDAESDVSGLNRTVNVY
                     SDNGEVLKTYTSKSMRVKDGDGGTITLDFDGKRVIICNAHVVIEENSSNK"
     gene            91698..91850
                     /locus_tag="KNP54_000366"
     CDS             91698..91850
                     /locus_tag="KNP54_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891297.1"
                     /translation="MKITISIEEAMDIIKQHYENKGIEIKDLSFNLEKTGMVRNIKFK
                     GEIILK"
     gene            91884..92483
                     /locus_tag="KNP54_000367"
     CDS             91884..92483
                     /locus_tag="KNP54_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891298.1"
                     /translation="MFISSTNRSDARSFHISDYYRTPITKIKEFLTEFSRYENILNSN
                     IKILDPCAGGDNTNPMSYPTAIQEFSNQEISIDTVDIRDDSRANIKQDYLKFQPKEKY
                     DVIITNPPFNLSLDIINKALNDVREGGFVIMLLRLNYLGGKVRQRLWGNNMPKYIFVH
                     NRRMSFTDDGKTDSIEYAHFVWQKGYNPKFSQLKVLISQ"
     gene            92509..92721
                     /locus_tag="KNP54_000368"
     CDS             92509..92721
                     /locus_tag="KNP54_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891299.1"
                     /translation="MEINRRRCEYAARTGRYPNSLILWEGYYSLLNIQYIEDKTRGYI
                     TKFNGMDVIKCNDFLKIELFEKNINN"
     gene            92750..95821
                     /locus_tag="KNP54_000369"
     CDS             92750..95821
                     /locus_tag="KNP54_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBF0891300.1"
                     /translation="MRYNNYHSHKIYSNIRSLDVITKPQQYIDRAIKLGQNTYFTTEH
                     GYQGNVYEAKTLCDEYKLKMIIGAEFYYVNDINEKDRGNYHLIVIAKNNDGYKQINKA
                     LSLANKNGYYYKPRIDEKILFEIFKPGDVVITTACVAGILKLENREELILKLKNYFKN
                     NFFLEVQSHPHKTQALHNKDVLELSNKYNIDIIHANDSHYIYPEESKYRTKFLKAKGI
                     NYPEEDGFILDYPNSEDIFKRYEKQNVLTKQEVERALKNTLIFDECEEITLINDDIKL
                     PSISKNPNKELKEILNKEWLEKRKNIPKNRWNEYLDAIRYEFDIIEKTHMEDYFIIDY
                     KIVQRAKQEYNGLLTKTGRGSAPSFIITNLLGLTEIDRLNAPVPLFPTRFMSVERILS
                     AKSLPDIDLNAEDAEPFIQSTRDLLGEENCAWMISYKPLQDASAFRLWCKANDMKLSE
                     YDEVAKNLDKYTNDVFWKDVIKESKVFVGVVESVSFSPCSMLIYDRPIDEEVGLLKTK
                     DGVCCNIDGYYCDKYKYLKNDYLTVKVWSLIRKICELANISIPTIEELNILLDAKTYD
                     IYKDKLTCTINQVDSDYATNLASKYKISSVAETSAFVASIRPGFASLLDNFINRESYT
                     TNVKELDILLEDSYHYLMYQESIMKYLIWLGIEESESYDIINKIKKKRFKEKELKELH
                     IKLKNNWIKKVGTENNFEDTWQVVNDAASYSFNASHSLSYAYDSLYCAYLKSHYPLEY
                     YTVAFNLYNEDTERTRKLTDEIEYFSIKLENPKFRFSKSEYFFNRDTNSIYKGIESIK
                     FLNSDIGEYLYSLKDNKYDSFLELLIDLQGHINSKQLSILIKLDFFEEFGKSNKLLET
                     YDIYNSIYSKKQFKRDNLPCDINTMRKYSNKETEKIFKEVDTKELCSYLESQIENTDI
                     PTNEKIQAHFEFVGSCNIKDSNSNPRYCLVIDIDTKYSPKVTLYNISSGNIKIFKVSK
                     PIFEDNKIDVYDLVYLKSIKEKAKSKKVDGKWIRSNTETEWWIQEYWKIEN"
     gene            95924..96175
                     /locus_tag="KNP54_000370"
     CDS             95924..96175
                     /locus_tag="KNP54_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891301.1"
                     /translation="MISILIDEQRYYSLLEEKKDLSMRIDELKEENAFLKQENEEYEE
                     ILNEWECVRKEIVATCKKKEILGEKPSELEMVLQKIEDI"
     gene            96175..96495
                     /locus_tag="KNP54_000371"
     CDS             96175..96495
                     /locus_tag="KNP54_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891302.1"
                     /translation="MSVNKIYEKKEYIIIKSKSGYIVYNTNKEFKEGHTHLKSYNAAK
                     TAIDLVIKRRLPKSYSIYFLTSLMRISNDVQYIKHISDIVYIRNNKGLKEKYINSKNI
                     KKNY"
     gene            96570..97691
                     /locus_tag="KNP54_000372"
     CDS             96570..97691
                     /locus_tag="KNP54_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HBF0891303.1"
                     /translation="MKSYKEKQFLVFEFEDGKNVKYNLATGEYVGKSGRIVKDVCTQL
                     RGYNLHEVINSFEDENYKCFLNFVDGRVNRSKSSRAWGRRVERIRNIGSFLNEINNYS
                     EYEQLFSAGLKKIIYPIHCDIKSIPKGLISICRNYSITLSDRLIQGYSKNPNLYNNLL
                     SLELNSIRKTNLISILDSGYDRMIFDRLIDIYKYKPQSLINYIDNLMTYEALNGLEST
                     LNELYDYVVMMSVISDKYEKYPRHFLTTHKIASRNYNRLKTQFEEEVFNKRIDKSLEY
                     SYQDYKFIYPKNTNEIKDEAVQQNNCVSSYIQNVIDGKCHILFMRKKDNPSKSLVTIE
                     VRNGKIVQAKGKYNRDVNEREQEAIDKYNNRIERMKKIC"
     gene            97685..98128
                     /locus_tag="KNP54_000373"
     CDS             97685..98128
                     /locus_tag="KNP54_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891304.1"
                     /translation="MLIEGTKIRLMKEIQGFEMLKIGDIFVITSVGNNGAIHFKTNYG
                     MGFMNYSELKKYFEVAIETKKKEHIWSEWRTATVFGTNKTCTYRTNGKKVEVRMGDFK
                     ASATCHDSDEFELNKGVELCLARIEVKKANKQVNLVLDKINNKEI"
     gene            98138..98293
                     /locus_tag="KNP54_000374"
     CDS             98138..98293
                     /locus_tag="KNP54_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891305.1"
                     /translation="MSCKFKERCENKNRDCDYCCYNPNAYLEDAFEWNGEGRKPTDEE
                     LDDALEE"
     gene            98337..98897
                     /locus_tag="KNP54_000375"
     CDS             98337..98897
                     /locus_tag="KNP54_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891306.1"
                     /translation="MRWRNILVTSVLVMGSSIHIFANTKEMSTSRMDKNIVADTAKNI
                     NLMYKYEWEQHKNSSEYKLEIKRINLEKDLGIKIEKLIPVTWEVSYYTSLNCENSKYG
                     AITATGEKLQYGFVANNYLKFGTKILVDGNLKVVKDRGSNKYFGNSNAIDVFVPKLEG
                     ESDYKYYKRVNNMGRHYKEGYIIVEG"
     gene            98909..99577
                     /locus_tag="KNP54_000376"
     CDS             98909..99577
                     /locus_tag="KNP54_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891307.1"
                     /translation="MNVNGIKIPGIIDVSNVYVYGIKESIIASGYPMYEQQVIDMKKI
                     NISEKDLKRANQLGKSKQGSGHDCFSKGIIIQMDLQWSEYMWRQWDRYHHNDYVSSQS
                     KMHRLSKFNLDDMCNKYVDKNTINFLNELIHEYNNFEELKLNNSNNIILRNGEKVEVT
                     KETLWKIIISNCPSGLMLTARVTLNYLQIKSMINQRENHKMEEWRILCDFFKTLPKYK
                     ELMM"
     gene            99623..100516
                     /locus_tag="KNP54_000377"
     CDS             99623..100516
                     /locus_tag="KNP54_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891308.1"
                     /translation="MAEKRINYNQVFVSGEVLDILNIARMNQGTGQEAIRFTLKVETA
                     PNESVNVDYFTSMFKSDGSPNQMFLGIETIANEIKTRAEDGKGDIVRCVCSLDNNLYY
                     KDGEKKERFQISGTFCNREKYDDKGNPIDDKGEVVKSIKASQVWRVYTLIENIEEKED
                     DLGKYLEIKGLINKYGKQGCNMTFRIHNEDMIEGFKSLYKIGDVGLLEGTVKSMVVSK
                     SAGFGSRIKKSAFTFLEIEGGDEPLKDGDKIFSDKNYPFTDKNIEAMREKIKEKDKKE
                     KQRDIDKNGKTIEIRDDDVPF"
     gene            100556..101113
                     /locus_tag="KNP54_000378"
     CDS             100556..101113
                     /locus_tag="KNP54_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBF0891309.1"
                     /translation="MEVKEKTMNDGFKKVVNEEIKTYISNLYSDRIDGLKESDSQIEI
                     TKALIAFHLDIESIPKDNTNPFFRSKYANLDTILKAVNPLLAKHDLILMQSAEDAGND
                     KVYIKTKLKHSSGEYIESNSAPFKPAKTNDIQARGALETYLRRYAVQSVLALSFEEDD
                     DGNSLTNKSKGKSEEENSTIKKSRV"
     gene            101174..101725
                     /locus_tag="KNP54_000379"
     CDS             101174..101725
                     /locus_tag="KNP54_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891310.1"
                     /translation="MNCKCRFCKKKLNTNDAYKVEHITSGGNKQNRYYCNEQEYRKEQ
                     QDIYFWKQCQLGIDYIMGYTVINNQKNKMLQEIIKGGYTREELYDCIIEKKDEVIELL
                     NYRKDIEEEYPKLCYVFTILKGSIRDITIKNKQMKYEKENERIYKEVEKSEEYYEIIA
                     PKKVIYNKRQSLFDKVKGVYQDE"
     gene            101766..103292
                     /locus_tag="KNP54_000380"
     CDS             101766..103292
                     /locus_tag="KNP54_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891311.1"
                     /translation="MVLGTMLKSLTLFSEYKISESDFIIDKVKFFFSLGRIMSKTHNE
                     LDEISVAKFVSSNKLKSEYERYGGWNSLSSAMEYGKETNIAAYIDDLAKNNLLIALDK
                     RGFNVIKEMEHNGLKFIPFEIFQSMKCREVEEFYEGLISSCSVNSIKNNMKVENLLLT
                     KDDREKLKQKTEAGTPYNIIFEYTEKEIGLSNNEESKYIYSLPILSNRTNGIGKGGGI
                     NIIAGFSGIGKTTLLFFNYILAMIYRGEKIVIFANEQKSQYFKSMLVSFIAYNIFNYH
                     DLDRNKIDNGDFTDFEEDLMEKIEKFLRDRCFAENLKFIYMEEFEISEILRKSKELVT
                     HQGFTGIAVDTFKSEDSSDAHYTGKLIENSKLLDSFGNKYNVITMLSMQLLTAQENKS
                     SYLSAGDLSEAKAVKNVCGLLKLMRKVVNELELDSTNKKFFLKPYKLKYNKLKKTTER
                     EYIQFDAKDLQKEYRLLFLNKSRRGQDGDVILLRFYGKTGRLEEIGRCEKVYRGQLSY
                     "
     gene            103302..104363
                     /locus_tag="KNP54_000381"
     CDS             103302..104363
                     /locus_tag="KNP54_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891312.1"
                     /translation="MEIKDLTNEQVINFMEYLGSDLSPKSNDRQLIFNTCLCHNGDSY
                     KLFYYTESKTFHCYSSCGHIGSLIDLLIHINKYEFKDAINEIKDFFGISNQPMLRKGF
                     RIKKKVEQIHDIKDIQIELLPTPKKPYVYKTFQQVPIEEWENENISFEVLKTYQVYYN
                     LYENQIVIPHFCWHDRARPVGIRVRNLDEDKAKSFGKYIPLWYDNRCYNHRLSLNLYG
                     LNVNKKSIKNSKKVIVFEGEKSVLQMATMYKNNPSVAICGSNFSREQKKILIDLGIEE
                     LIIAFDRQFKVKDDEEYVIWRDKIYKLVQDIKDVVNISVIWDKYNLLGYKDSPSDKGK
                     TIFEKLLKNRINIENFVKQ"
     gene            104468..104740
                     /locus_tag="KNP54_000382"
     CDS             104468..104740
                     /locus_tag="KNP54_000382"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891313.1"
                     /translation="MIKFLIKNVHMGDKLYCINNIGNYKKGEIYTVSDTSFFGLFHKT
                     KGENCLPIECYFIHLPKKEELESNPKSMTKEEIEDELGYKIKIVSK"
     gene            104761..105612
                     /locus_tag="KNP54_000383"
     CDS             104761..105612
                     /locus_tag="KNP54_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891314.1"
                     /translation="MSIFNKKYGRNVKITEEEPPSPPPKQPIYNRDNIQYDKEMERKL
                     LDIDRLKIELEKEKKIEEERKKVERVKENEGKEWAWVEGYKCTDKNMKCKEFQYELNK
                     AYSMDGDDINIWNWGFHLCLDLGDVFQYYAPNLSNRFFKVKALVKKADKYKYGKEYGE
                     VTLLSGSVLRGHKINKIAAKEIIFLEELTFDKLKLHIQNSFPEVNTKSKWYAICKLGE
                     QEYYHRMFMNQMKKIRFSDTFSQLLFDECRNYCEILEILNKAIAYSKENLSKDMIIYL
                     LMKDIRK"
     gene            105636..106079
                     /locus_tag="KNP54_000384"
     CDS             105636..106079
                     /locus_tag="KNP54_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891315.1"
                     /translation="MDKINKIDLIKLKEMNIYDNYQLKKIASKMILHLRYEIMDFCGC
                     GSPEDISFMIKGVLTAIQNKEKNCNLEYTERCYIFEIEFNNVCGIIGSKNDLIQEFIL
                     NALNSYGLLEHGSSIWGSWLSDYGKQILCAFEIVGDCILDVSYLD"
     gene            106106..106765
                     /locus_tag="KNP54_000385"
     CDS             106106..106765
                     /locus_tag="KNP54_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBF0891316.1"
                     /translation="MIKYVMSDLHGMYDKFISMLEQINFNSNDHLYILGDVLDRGDKS
                     LEIIDYIRKYKNITLLKGNHELMFQESYTDVNSSFLWFYNGGKDTFYDLGMKSYEYKE
                     NFYKYIKNLPYLEIIDNFILVHAGLYLPNNYENLSIEQIIELQEEDICVWDRTILNTN
                     KHIKGYTIIIGHTPTQNIKDYEKAEIYKQEGIINIDCGACFDNGKLACLRLDDMKEFY
                     I"
     gene            106776..107303
                     /gene="yyaC"
                     /locus_tag="KNP54_000386"
     CDS             106776..107303
                     /gene="yyaC"
                     /locus_tag="KNP54_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBF0891317.1"
                     /translation="MDILKISYNNLNAISKISEVLRDIVNEDTLIVCIGSDRVLADSL
                     APMIGSILEKSTIRNKIFGVLGDSIHALNLEQKIQAIKNNYPNSNIIAIDACISKISD
                     KGTIIISNKPVKPGLGVDKKLLEVGDYSIVGIIGRNKYDIYDTSDPELILDLADVISK
                     SLISILLEKEERMIV"
     gene            107300..107554
                     /locus_tag="KNP54_000387"
     CDS             107300..107554
                     /locus_tag="KNP54_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891318.1"
                     /translation="MIQEVRQEILLKNGLILYTGDLVEIKYKSDEDVIEHTCKGKIKE
                     AKELFIKLDTSKKYKTSERMIYSWELKEIKKVDDEDEKDN"
     gene            107538..107795
                     /locus_tag="KNP54_000388"
     CDS             107538..107795
                     /locus_tag="KNP54_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891319.1"
                     /translation="MKKIINSKYRALYLFIFFLIFNLIYSLYFGRNTEIGFYSSTSCI
                     EEYILDIITSIGLFFSMMLAGFDVTENFINSLRDYCEEDAK"
     gene            107806..108015
                     /locus_tag="KNP54_000389"
     CDS             107806..108015
                     /locus_tag="KNP54_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891320.1"
                     /translation="MELKDYISKVELNDMPLTLDNKYMLNEISISEDSKIFAVKDTSG
                     ITSYYTEIEFNKLFRGINSILENII"
     gene            108090..108929
                     /locus_tag="KNP54_000390"
     CDS             108090..108929
                     /locus_tag="KNP54_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBF0891321.1"
                     /translation="MEKELYSFSKLNAFNTCPFQYYLTYVKNLNREQSCYGYYGNELH
                     SLLEQLQQRKITNQEAIQKYNEVIEYANLMDYNFPTPNSRINYLECILHYIENFVPIE
                     CDRYYIEEYFEFDINGITMRGYIDLYYIIGNKIYVIDYKSSSKFSKKDLPKKSMQLIL
                     YAMYLKEKYPDKIIEYVAFDMCKYMNNEKGVLIERNKIDSINDYERAIVKIKYTKELE
                     KQLIDFVVDTVTQIKQLDSNDESVWCKSDDKSNQFFCKTLCSHYNKGCKHKENKSFRK
                     SKS"
     gene            108967..109263
                     /locus_tag="KNP54_000391"
                     /pseudo
     CDS             108967..109263
                     /locus_tag="KNP54_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895083.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            109280..109861
                     /locus_tag="KNP54_000392"
     CDS             109280..109861
                     /locus_tag="KNP54_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBF0891322.1"
                     /translation="MDKLKNIFVFLGYSGSGKDSIVTEISKQFNIPILISHTTRPPRN
                     YLEIINKTYYFVDNKFFKKEKNNFIEMRKYIVHDGSTWLYGIHKSELENKKYALTIVD
                     ASGYKALEKYFTGTKTKLVPFFINADEDTIRKRLIDRGDNLKEIERRLVDDKIKFKEF
                     LNSENYIVIANNLSITNAVEQVKIHMKEGIQWS"
     gene            109852..110346
                     /locus_tag="KNP54_000393"
     CDS             109852..110346
                     /locus_tag="KNP54_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBF0891323.1"
                     /translation="MVLALDVSMSSTGWAVINRNKNILKYGKIVTKKDKFKSEDERMC
                     YICNAIQELIITHNIQIVLIEDQFTSRNSKTILSLRKLLGAIMRTVKLNNIEIEYMYP
                     VSIRKYLLNNGKAKKEEVAAYVRENIIDIGEYIDRTCKAKTSDIYDAIALGIAYLNKL
                     DTNR"
     gene            110370..110873
                     /locus_tag="KNP54_000394"
     CDS             110370..110873
                     /locus_tag="KNP54_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5'-triphosphate
                     nucleotidohydrolase"
                     /protein_id="HBF0891324.1"
                     /translation="MSINVKIKKLNQNAIVPSYAKEGDSGIDLYTLKDTVIPAKSAVA
                     ISTGISLEIPYGYEMQVRPRSGISLKGMFFTRYVTIYDKVQPKKQIRKIFVAHPTVRL
                     GTVDSGYRGEIKIITYNEEDFDILIPKHTKLAQGVFQQVPRAILKVVDELTSSERGSN
                     GFGSTGI"
     gene            110874..111014
                     /locus_tag="KNP54_000395"
     CDS             110874..111014
                     /locus_tag="KNP54_000395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891325.1"
                     /translation="MNKYIILEKYNYYYDDKCMTLYHLENIYTGLRFSIEKIELEYYN
                     IS"
     gene            111038..111211
                     /locus_tag="KNP54_000396"
     CDS             111038..111211
                     /locus_tag="KNP54_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891326.1"
                     /translation="MYRYDDYVNLINDLELPKEIRNKCVRVIMTLENMQDIMVVHKFK
                     TYVVNEKYIEKVA"
     gene            111331..112080
                     /locus_tag="KNP54_000397"
     CDS             111331..112080
                     /locus_tag="KNP54_000397"
                     /inference="COORDINATES: protein motif:HMM:NF019976.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009617778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HBF0891327.1"
                     /translation="MFKEIFEKVFMSEEVSKTVKEVNNIIKDTKIQVKGGFGELRLDF
                     ILSRLGKDYIIIKDIIVPGSNKTTQIDSIVISMYGIFVIECKNFSGYIYGNDKDKVWT
                     QIVGKTKNTFYNPVRQNYAHIKAIENIIGNKYNIYSIIVFSDKATLKNVMISGNNIIV
                     INESEILSTISKCKDVTIDKEEIKIIRDKIFDCMKTTNQNTREHVRNLKNITEEDKCP
                     RCQIGHLIKRKGQYGEFWGCSQYPKCKYTRK"
     gene            112369..113481
                     /locus_tag="KNP54_000398"
     CDS             112369..113481
                     /locus_tag="KNP54_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBF0891328.1"
                     /translation="MNAFIRKRNKNYVVYLEFRDDESGKRKQKNMGAFDKKRDANKRL
                     AEVKDSIYKDSFLVPNEITLAGFILDFLEKYKDNISASTYKSYIAICKNHINPSIGKY
                     RLQELRNIHIQNYIDDLAGNLNPQTIKVHINVLRLAIKRAYRIKLIKENIIDGIESPR
                     IKKFKNEIYDKEQMLKLLELAKGTNMELPISLAIGLGLRLSEVLGLTWDNIDFDENTI
                     TVNKITSRLDGSVILKEPKTESSVRKIFAPIELMNLLKNYRLEQNKKLLRSIVRNEYN
                     LLFFDRKGNPIAEDVMSKKFRKFLENNDLPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNINTTLNVYSHVLKEMDKEASDRISENLFKAN"
     gene            complement(113979..114173)
                     /locus_tag="KNP54_000399"
     CDS             complement(113979..114173)
                     /locus_tag="KNP54_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891329.1"
                     /translation="MPELEINISISIPIFLVISYLAIVSIVMLGISALNNFTNITSVP
                     INALGSTVGFVIFQLLVSFF"
BASE COUNT        43078 a        14481 c        15560 g        41702 t
ORIGIN      
        1 taaccaaaat tccattcagt ctgcattttc tcactctcct ctctaacaat aagttattaa
       61 ctcatttaca ctagttgcaa tattagataa accaccattt accttttctt ctagattaac
      121 aaatctatct tcgattttct tagacgaata agtagtcatt tcagatactc tgttatcatc
      181 tacagttgca ttaataaaat gagtttctgc atttccattt atcacataaa cgtttaattc
      241 tgaccttgtt tcacttctaa tttctataga attatcatct ataattttaa aatttgtaac
      301 tacattttct tttgtagtag catctataat atttacaact attctctgtg ttaacaaacc
      361 atgtgttaca gttgctttaa atccattttc tgtatcatcc acccaatcat caattgttat
      421 tgtttgagta gatgccacat ttgaaccacc tgcgataagt tggtcaattt tagtattcaa
      481 ctctgtttta gcagtttcta tatttgtatt aactttttct atttctgtat tagtgttatt
      541 aggtacattt tttaattttt ttactacatc ttcatttaac aatttatcac cttctttttt
      601 atttagagag ctacattagt aactctctat tttgaacata aaaaaaagaa ctcttacagt
      661 tctatgataa tgaaatctct agtgcttcac acatttttct tacttcttct cgatatttaa
      721 caggtacttg gtcaattgtt tttaaacctc tctctatcaa tcctacataa attgctgcca
      781 tactacttcc tccttcattt aattttatat tttttaatga catagtagat gtctgttgac
      841 tacttaatac catttcgcat atttcagcag tcgctaacat taaatctgtt atgtcattat
      901 cttgcgtttt ttgacttgaa tctaaatcat ctaattcttt tctttgtctt gacttctcaa
      961 ttttttcttt atctattttt atcatttaat cacctcttaa agtgtttcaa catctaaatt
     1021 gaataacata gatggttttt ttatagttgt attagtgttt ccttcttcta ctattacttt
     1081 aggttgtgca gattgtatat tcatatcttt taactcatat atctccttat atccattctc
     1141 agtttttctt gtctctactt taaccatatc tttaaatgta tctgattcat ttatctttaa
     1201 ttgtactttt aatttattta ctaaatgata aattggattg ttagaattta aatcttctaa
     1261 cagaccttta ttgagtgtaa gtactacatc ttgtgaatta tcaactatac tagatacatt
     1321 ataagtattc ccatcgatta atacagttga atcttttact atagttgctc ctgtttcttt
     1381 tttataaata taaacattta tatataaatt atttccaatg tcagaatgtg ctttaaatac
     1441 aatcttattt tctccaagaa ctaaattctc tggattaatc tcaaacgtga ctgttcctgt
     1501 agataagtct tctattatac ttgaactaat attatttata aacatctcta tttttgtcaa
     1561 ttcattattt ggattttgca aatctatttc aatagatgag tatgacttat tctttatttc
     1621 caaacaagtt ttctctgaat ctacttttga gattatatat aatgtttcat cttttattaa
     1681 agcatccact atatcattaa catctcttgg aatatatatt tgtgagaaag tatataacat
     1741 agaaccaatc tctacatctt taattttata tgtttcctta tttatccctg taacatacaa
     1801 agtcttatca ttttttataa caaatatatg tttatcatca taagatttta tatattttac
     1861 attttctaat actttagtaa ataatttaat aattgtattt tttgtattct cattcagtcc
     1921 taaaatccca tttatattat atccttgtac gtataattga ccttctgtag ttatagccaa
     1981 tatataatta ctataagcat atatctccct tatattagaa atagttaata cttcttgtaa
     2041 ctcattaacc tcatcattat gccctattcc aagttgatat tctgagtttt taccaataga
     2101 aaacaatgag ccatcatttt ttaagaagta agtaaaatta tcaccacaag caatatctat
     2161 tatatttgtt aagttaattt ttataaattc agaagttgtt gttagctcag atttatttat
     2221 agcaagttcc ccaaattgat ttgaaccaca accatagaca tccccatttt ctaatatcaa
     2281 aattgaatga gttgatgata aagacatctt ttttatatta tcaaaaggca atgaagttga
     2341 gtaatttcca gcatttgtgc caaatggtat tctataatta atactatcat cattatgtaa
     2401 aaatatcttc ttatttacta atagtccata attatttctt ataatagaca tttcattaga
     2461 aaaacttaaa tcactaggat tatcaccaga agtgtttgca atctgatttt cttcatgtcc
     2521 attaaaaata cctacttgac caactacagc attacctttt ccttctaatt tattattagt
     2581 atattgaact ataagaccat tatgctgtgt atatacctgt tttacattaa ggcaatttct
     2641 aacaggtgtt ttttgtacaa catcagaata attattgatt tgacccaatt gtctactacc
     2701 aaacacatat aaggcattat cattatctat ataataagca tttttaccat ttgcatatat
     2761 gtgctttata ttacttgtta atttttttaa tactacagta ccagattcat taaaacctat
     2821 accatcatca gcatttcctc cagaatataa atctccattt tcaagtaaaa caaaaatagt
     2881 gtattctcct agagcaacct cttttatatt actattaaac gctaaatcct tatatccttc
     2941 aatatatcct gatgaattat tatatgaagt accaacacct aaacctccta atgagttata
     3001 tcctgtgaca aatattctat ttttcattgt aattatagtt ttgccttctt ccaacattaa
     3061 atttgatata gttgatgggt ctgttaatcc ttcaatattt attttagtta aactgtttga
     3121 atttgtattt gaacttatgt aatttctatt tccacaaccc attaaagaaa ttatattatc
     3181 attctccaat aatataataa aaacatacct tccacaaaat atatccttta ttgttccaga
     3241 aatatttact ttagtaaaag tatttctatt aatattatcc cctaatccta attgaccata
     3301 gccatttgaa ccagttgaaa ataattcatt gtcataggtt agaatgtaag aagatttgta
     3361 acatgttatt acttttttta cattatcaat aggcacctta gtaaaagtac ccctatcaat
     3421 attatctcct aaacctaatt gccctaagtc atttgttcca attgaataga cttgattatt
     3481 atttgtaaga ataaataaac aatcattcga tggaataaat tcttttatat tatctatagg
     3541 aacttttata aattcagacc gagctttaat tgtccctaac ttgttaccag cattattacc
     3601 acagacatat ccttcgctat tatttaataa tatatataaa gcttgtctat cacttttaat
     3661 ttcttttata tttgatatga tatatttttt agaaaattgt tttgatatat ttacaaaacc
     3721 atcatgtcta acatcataag gtttttttat gccaaaacag ccatgagaat ttactccaga
     3781 acaatatatg ttcccaaaat aatctttaat tactatcctt aatctactag catatattac
     3841 ttgtgaatta tatgcaaaaa aagcatttga taatgtgtat ttttgactat tagaataata
     3901 actactgtct cctctttgcc cacctgcatt tctacctctt atttcaaatt tagactccat
     3961 ccttgtttta cttgttgtat ataaaagatt gtctgttcca agataatgat tataataagg
     4021 catagaagac gatataagac ttcttaaacc taaattcttg tcttgggatg aagctccaaa
     4081 agtcgaaggt cttcctgtga attttatttc tttatatcct ccatcactag catctaataa
     4141 taaacataaa ttatagttag aaaccagaac ttttgataat ttaggttcat ctattaaaac
     4201 tgcgacttca tttgcatttg agtttttact tcctacaaac tctccaaacc ttgaataata
     4261 atcatcagtt acagaatttt taatacttgt gctataataa ttatgtctcc cagaaacata
     4321 gtagttatta gacgtagttc taattaaaca tccattatta aaaggaataa tttcagcaat
     4381 gttagataca tctgatactg ttgtatctgt tttatatctt aaatatttca tcttaacaaa
     4441 aacgctccta cttgaggtat cattaagact taattcgcca aaaacattat atcctgctgc
     4501 ataagatatt ctgctattgt ctatgcaata tgaagaattt gaatatgcaa taatttcatt
     4561 tacataagtt acagtactta ctttagtaaa aatatttcta ttagtattgt cattaagtcc
     4621 taactgccca taattgttta aaccagttga aaataattca ttagtagttg tttttaataa
     4681 cgcatggtta tctcctacag aaattttgtc aacagaagaa atatttactt tagtaaaagt
     4741 atttctatta atattatccc ctaatcctaa cactccaaat acattatatc ctgttgaata
     4801 taatgtatta tcacttagta atataaacgt gaaatatgag cctagattta aatatatatc
     4861 ttttatagta actccttctt ctaattccaa tggcactcta gtaaactcat aacaatgacg
     4921 attatgacct aaacctaaac ctccataagc gttgtatcct gctgcgtata gttcattacc
     4981 attcacaaca ataaatgtag aggtgtcatt tgctttcact aaagagatat tcacaaaatt
     5041 attttcaagc cctatatcta aaactctttc atcattttta tttattaata atctattatc
     5101 aatagactca atatgattac attcttcaat atcaaagtcc tcaaattttt caaatccata
     5161 tataaattta tcatatcttt ttaaataaga aaaactataa ttgttatctc ctgtcatata
     5221 caattcattg ttgctagtta atataaagct tatagcatga gcacatttaa ttttacttat
     5281 atttttaata ctaatagaag attttctagg agtatatgtt gatctatcac aatttatttt
     5341 atctcctaaa cgcccatctg ggttggctcc agttacatat atatcattat tattagctat
     5401 ataaaattta tgatatctac cactttctat attttttaca ttagatatag atagttttgt
     5461 taagactgtt actgtagctc ctccaccaac accaacttgc ccacttgaat tatctccaca
     5521 accatagaca tccccatttt ctaaaagaaa atttacagca ccttgagcag tagaaatctt
     5581 tattacatta tctaaattta ctttagtaaa aatatttcta ttagtagtgt cattaagtcc
     5641 taactgccca taattgttta aaccagttga aaataattca ttatttaaag ttaatatata
     5701 tgaacaactg actcctgcaa atatttcttt aacactcaaa ttatcaattt tagtaaatgt
     5761 atttacagta gatgtatttc ctaagcctat ccctccaaat ttattattac cacatacata
     5821 aagctcgttg tcatttgtaa ctaacataga atagccattc ccacaagcaa tttgttttac
     5881 attacttata tttatcttag taaaagtatt tctatcaata ttatctccca aacctaactc
     5941 cccatctgtg tttaagccag tagaatacac atctccgtta tttttaagta aaagagaatg
     6001 agttccagaa gatgaaacat acttaacatt gtcaatatct atttttgaaa aatatcttat
     6061 aggtgatact ttatttccaa gtcctaaatt gccaaaaaca ttatatcctg ctgcatataa
     6121 ctttaaatca tccttaatta taaacacaga accagaatcc atatctgtaa atatatcttt
     6181 aacattaaaa gtatcaaaat ttttattaaa ctcttctatt ttaaattctt tgtttccaaa
     6241 taaagaacct ctttgtaata gtttattctt tttcatataa ttccccctat ctcacttcgt
     6301 aggaatactt gtttattttt atttcagtat cacctttttg ataagattct tctgttttag
     6361 tttcactata gttgcttcct aaatcatgaa tatatcttat tttgttgcat aaaaaaggaa
     6421 ctgttacatt tttaaataat acagttccac tatttgaaag taactctaat tgttgcttaa
     6481 atttattaag ctttaaacca tctaaattac ttatgttttt agaatcatat agggtatcat
     6541 accaataccc agcttcatct gctgtagctt ccttatctaa ttctaattca aatagaattt
     6601 taagtatttc cacagacatt ttattataat tttcttttaa tattttcaat tgctcgtttg
     6661 tatttccacc agattcaaga actttaacac tagcatctaa ttcatttacc gcatctgata
     6721 tatttttaga tactgtactt aattcactcg aaccaacttt actttgtatt agatttattt
     6781 tctctaagtt agtagctata ttacttttat tttcatttat cttagttaga ctctcatcaa
     6841 attttgcatc aattttaata ctagagtaag tactatctag tgttgttata ttatcattta
     6901 ttgtagcttg tataacttct ttatttgtat taccatttac aacagttact tttacatcta
     6961 tgttactttc attaaatatt tctatcgtat tagaatctac tgtagtataa gaattagtca
     7021 tacttttctt agttgcttca tctaatattg ctacaaatat attttctgta actaaattat
     7081 gattaactat aagtttaaaa tattctccat cagcaaccca atccgattca acataagatt
     7141 tactaaaagc tacattagtt gcagcagaag tcatttctgc tattttctcg ttaactttct
     7201 caaagtcata tgttaatcta tcctttaaag tatcctttac agttccatca acactttctc
     7261 tagcttgtat taattcgcct ctagcatcaa gactttctaa ttcttcaaac ctattttcaa
     7321 attcagttat tttattacta acagttgttg tcatatcagt tttagcagta tttacttcaa
     7381 ctattttgtc atctacttct tttatctttg tatctaattt tgtagtactt tcatcaatac
     7441 aatcttctac attagatata gcttgattta cttcatcaag tttgtaatca atttgctctt
     7501 ggttatctgt aagtttatct tcaaatgtct tatcatacaa atcaaaagta ttattagctc
     7561 tagtgtctaa gtcttgaaac ttcttgtctg tctgaacttg aacatcaagc attttatcat
     7621 cgactatatt atctatttct ttagacttag catctatcat ttcatctaat tggagttggc
     7681 aatctgtaag tttatcatca acttgaattt gcatattctg aatggattct tcacgatttg
     7741 cctcttgatt ttgacgtgtt aactcattaa actctctttc ttcttcttgt atgtttctta
     7801 tatcttcatt ataaatccta atctgctctg ctttatccct aacttcttca tttccaagta
     7861 tagttatttc aagctgttca actcttttag tcaactcttt attatttttt ataatctctt
     7921 ctgcttgggc tattattacc aataatactc catattcatc agttgaggtg atatcatcat
     7981 cattaatcat accctcttca actctataat aaagatttgt agtattgagt aaagttccat
     8041 ctttcacaag ggatagttga aatgtattta taccaacaga agcaagtgct tgtcggctaa
     8101 gttctatctc tacaatacca ttttctgcat ctacaacttc acattcacca ttaacctttt
     8161 gtccatcact ttttgtaatg ctaactaaaa ctctatcata ttcagataaa tctattattt
     8221 catctttatt tttcaatata gcttcaatat aagctgtttt aacatcattt tcattataaa
     8281 taaaataatc tagcaatctt ttgtttattc tataattact aaagtcgacc tctatggtat
     8341 gattctttat ttcataattt ttcaaagtat cacatcctat tgttctttat tttgttcttc
     8401 tagttctttt ttcaagttct caatttcttc ttgttgttgc atgttgagtg ctttataaag
     8461 tattagttca ttatataaac tttttatctc ttcaaatgct actgtatatg ctttttgtaa
     8521 atttacttcc atattaatat cctcctaaat tattaatttt ctcgtttaat tcattaatta
     8581 tcatctctaa ttcttctctt ttttgtattt cttcttgaag tgcagttgct acaacagttg
     8641 tataaccaga tgggctaaac attaatccat tttcttctcc atagtcatat agaaatgttt
     8701 ttccaacata actatcttta aaatcattag ctataaaccc tatttgacta tctgcaattg
     8761 tcctatcttt ttctgctata taatcaaatg ttgctggttt aaaatcatct cttataaaat
     8821 ctaaaaatgg tgttggagtg atacttgaac gagttctatt cttaatatct tttatgtata
     8881 ctatattctc tttaaacttt ttatcagatt cactcagagt agaacgagca tataaatatc
     8941 tccatttata acgctcacaa cctaaatcag ttacagaacg ctctggataa aatgaatatc
     9001 ctacacctaa actatctcca tttgtaaatg taaaagtagc tccaccacat cttacaaaag
     9061 tatcatctct ttcaacaata aagtgttctt ctccatcaac ataaatctca gcagtatcat
     9121 atcctaccca aaaataatta ttgctatcat attttaatct tattgctgag gcttgactag
     9181 aaccatctga ttgtcttgca tctattgcaa atccagacct gctacttcca aataatctga
     9241 ttattggttc atgtccagat ggagtagtta atatatcaca tgctatagct ccttgattta
     9301 ctgttagacc actcctgctt atctctacat aatttgatat atcattaaat ccaaattcaa
     9361 ttttatcagg tttaattcct acaattgagc cagagttatt cctcgtaacc atcatggtta
     9421 tatcatcttt agttaattta atttcagcag catttgtttt agttgcacca tcaacttttg
     9481 ctacttctaa ttttatttct ttagctgtag catttatctg tgaaaattcc tctgatatac
     9541 ttccacccat acctgttatg taaattttat cgactgtatt tttaagttca tttatcttta
     9601 agttatattg agcatttgca tttatagcta aaattctgtc tgaaggtgta attatactat
     9661 ctgaaataac tgaattaatt atagagttta gattggtact tgctgcatcc aatgctgttt
     9721 ttgaagtgtt tattgctact aagtctactc cagtagttct atcaataagt ttttgtagct
     9781 ctgtatataa acttgctttg tctgtatcta ataaattaag ttcaatatca atcttttctt
     9841 tttcttcatc tgtaacttca ttatcattaa aataattaga catattagaa ctaaatgtac
     9901 ctaaatctgc atttaactta attatagctt tatttatgtt ttctcttaat gttatatttt
     9961 cttgtgaacc accaaaattt ttagtaactt cttttactaa tatatttaca ttttcagctc
    10021 tttggtctat aagagacata ttttctttta tatgagatgc atcttcttgt acttctaaaa
    10081 ctgtttgatg tattccatct atatcttttt caataactac aaacttttca ttatgctttt
    10141 catcagtctc atataatccc caaatctgtt cttctgtatt ttttcttgaa ttaccatcaa
    10201 atgaaatatc aaaaatagaa gaatttatag gaacttctgt gtgttttcca ttgtcattta
    10261 caactactaa aaattgtgtg tttccctctg gtaatcttac attagaaact tttaatgttc
    10321 ctggattatc agcatcccag tatatatatt ttttatttgt ctctgtatct actacttgat
    10381 aaagtgtatt gttgtaggta acaattactc cagtaattct aatccatgaa tctgctggtg
    10441 aattatctaa tatcaattta catcagctcc ttttgtatat ttttcttagg aatatattca
    10501 tctggtagat taattctttt cttctgttgc tgaataaata aatgtctctt agagtttaat
    10561 gttctcgttg cgtgttcagc tttagtcaaa tagtcagcta tagtcctttt gtcatcttct
    10621 tttacttttt tattacttaa agttaattct aaagtatcca atttcccatt tttaaaattt
    10681 tgagtaaaag atgtaaaata gactaattct tcttctttag attctttgct atgtaacact
    10741 ataatatctc ccagacttaa atcacccttc caatgttgtc taaaattaat atctattatt
    10801 ctatctaaga agtttataac atccagagtc cactctttgg ttggaataca ttttaaactt
    10861 aattgtctct taccttctgc tattaaatct tcaactttta aaaaagcatc atttgtataa
    10921 gtgtcataat agagaaactc atttaactca tccaatagag cctcattaaa tattaaatat
    10981 ccatcctcat cagtcgaggt ttctctctta caaagaatat ttatatcttt tatactttca
    11041 tctaactttg ctatctcttc ttctaaatgt tttatttgaa catctaatat gaccttttta
    11101 tcttctagtt cacttatttc tactgctaac ttagctgaat ttacttcatc tttatgttct
    11161 ggattatcat aagttttctt tatatccttt ttagccttta tagtctctat tacatgtaac
    11221 cattcattac ttttactatc acgttctctc tgtttcttaa gttttgtatc tattagttct
    11281 ctccaaattg gttctcttat ttcattcatt tcctggtatt tctttatagc tctactaagt
    11341 tcttcactca tttctttatt gtctaagaaa taagaataat tctcaatgta atcatatcct
    11401 gtaactgtag ctcctattat atccatatct tcactacctt caagcttcag tctagttact
    11461 atatcatcac tatttgtagt tctttcaagt gattttatgt agttatcatg agataaatat
    11521 aactgaatgt tatctccaaa actgtctata tgatacaaat taactaaatt attataagtg
    11581 tcaaaatcag ctatacactc aaattgttct tttagttcat tattgaaata atctaaccaa
    11641 ttagaattaa tactctcttg ccatcttact ttttctctct tattaccttc actatcagtt
    11701 tcataagcaa ttgaatcatc cacataacca agtttccagc ctgtctcttg ttttaaataa
    11761 tcattaagag atataataga tgcttcttca tctttggtaa acatctgtaa tccatagtcc
    11821 tcaatattca catcaatttt tcctagttta acttctttag atttagctgt tactactttt
    11881 aatttatcgt ctgtagtcac aacattctta actacaaaat attctttatt attaagacaa
    11941 ataagacgtt cttcttttac ttcttcaaaa atgggattta ttattttatt aaataaaaat
    12001 ctatctgtaa tatattttgg aatggtcagt tgtatttcat ctactccacc aagctcacgc
    12061 tttatagaat ttaaaaagtt gattgggatt tgacctaaaa atgatttgtt catcttgtga
    12121 atggttaatg tgtaatcaga ttttatctgt ttaagattca cattaaaatg catattttat
    12181 caccttcttt gtattagaaa agcccatcaa ttaagatgag ctaaaatatt ttattaatct
    12241 aaatattgta acaagtttaa tagcttgtta catatatgat aaagcaaaaa accactcaaa
    12301 cgccaataag agtagtttca aaagataaat tgatttttaa ttaactttaa ggaaacaatc
    12361 actctttgta ttaagtagat taaattcctt acttttatta taccacagat acgttttttg
    12421 taaaacagat tcgtttacag ttaataaata aaaaatcact agataaagac gattactgat
    12481 atcaactaat acatatttaa aataggtata ttataaatca tttcattatt caaaattcac
    12541 ttcaatatct tcaaggtctt tttcattaat atttaggtct ttcagaatat ccctttgaga
    12601 tattagttct ttttcatcta tatctttcat tcttatttct gcctcaataa gaagcttaca
    12661 atcttctata ttatttatca tttgtaacac ccttaaatat ataccagaat agaaaaatag
    12721 ccacttttta aggtggcata gataagtagt aattcttatg taaaattttt aaattttctg
    12781 ttatctgtat tatatcttta ttctactcct gtcgtcaata taatattaaa tttaacatat
    12841 tggaaaatta tggtataata tttttagaga ctacagttta gactattagg gtgatggctc
    12901 tttagttaaa atccccagta agaaaggggg tgagactata gagtacttag ttttgttttt
    12961 aataatgata attatgatta caagaataat caatcatttg acaaagctaa tagatgcaat
    13021 cttaaacttg aaagcatcta ttaggaaact aaagaatcac cagactggcg ggtctagtga
    13081 ttctgaaagt aatacataaa tctattcttt ttattgttaa ctttaagaac tacaccctac
    13141 agcaaatagt ttgtagtctc ttttttatgt ccctatgata taaatttata tcatttatat
    13201 tactattata ctccaatatt atcaaaatag tcaatgttgt cattatcttc attgaaaaat
    13261 aaaaaagcta tattattaat agaataactt cttagaacac aatattcttt tacaattgta
    13321 gacaatataa tattaaattt aacatattgg taatttatgg tataatattt ttagagacta
    13381 cataaaaaaa actattaggg tgaatcttca tatacataag ccttcccatg tcaaatcaag
    13441 aggggaggtg atatgatatt atgaaatatc taatttgttt gttaacgata ataacatttc
    13501 ttacaactat aattattagt ttgattaagt tggttcagaa tttaaataga ctctttaaag
    13561 aaatagatga gtttaagaaa acgttgcaaa aaattaagaa tcacccgaac ggcaattcag
    13621 gtgattcttc ctctaattaa cacttcgctt atttatgaag agacacccta gcacaaatag
    13681 ttgtagtctc tttttttatg tctttatgat ataaatttat atcatttata ttactattat
    13741 accatataca tattattttt tgaaataaaa tctggatttt attagagaaa tctggatttc
    13801 tacttaaaat cctttgtcta tataaataat ctatgattta atattttcta ctatttttct
    13861 atatactcta ttctctaaat ctctaccaaa tttttccaag tctttcatag tatccttagt
    13921 tacatttcct tgaacaacaa agaatggtga attaaaatta actgaagatg ttggaaatgc
    13981 acttcttgaa cgagaatttg aaggaggatt ataattaggc atagcaaact tacttaaatc
    14041 taattcatct aatatgtcat taatatcttc taatgtctct ttaccttctt ttagtgtatc
    14101 aagccattct tgcttagtaa cagaacccat tgccaacatg ccatcttcat atttgtttat
    14161 gtattcaatg atagcatctt gaagtttctc aacttctcca tcaagaccta caaatttacc
    14221 agaactgatt gcttcattaa ttaaatcaac taaattttca tctgagtatt ttttctctaa
    14281 ctcttctttt aatttatctg cttcttcttg tagtctgtca gactccttat catacatatc
    14341 attgacttgg tcgtctacat ggtcttgtac taaatcctgt aatttcttct gttcttcttt
    14401 taattgtttt tgtaaatctt taagtttctt ctgaccactt aaagaactat ctctttcagc
    14461 tattgctatt tgtttttcta aatcacttat tacatcttgt tgttcttcat aatcatcttt
    14521 atatttggct tcttttcttg aatcattgta agcatcttgt tgctttttaa gagaatcaat
    14581 tttagcttta gtttccttgt ctatttcttt aagtctctct tcaagttctt ttttatacat
    14641 gtctctaatt ttctcttgta gactttgagc ttctttgagt tggtctttat aagcatcttg
    14701 aatttcttta tttaatgctt caatttcttt cttagattca gcaatttcct tattagcatc
    14761 aggtatttta tttattaata aatccaaata tccctctgct gcatcttcca ttcttttaaa
    14821 ttcttcatca gtcatgttct ttttaagttg atttttatgt tgaatgaagt tagttatatc
    14881 gccattatct ctaaatgtaa atccatagcc ttgtagcttt tgttgtagct ctttttgtgt
    14941 ttcttgaaga tatgctgttg tttcagatag ttctttagcc ttcttggcca ttaactcttt
    15001 tttcttttct aacaactcta tctgctcatc acctgtagca tttttaagta atacatctat
    15061 cattgctatt tcattattta cttgctctac atctttgtac atagaagtcc atgtggaatt
    15121 cttattaagt ttccacattt cttcttgtgc tttccttaat tcctcattgt gttctttaat
    15181 tttattattg tattcttccc attcttgctc acatttaggc agttctgtaa atgtaacttt
    15241 aatatattct tcaaggactt tcttagtttc ttccaactct ttttttctgg attcatcttt
    15301 tttattttct ttgtcaccag actttgaatt taatttgtct aattcttttt ctattgatat
    15361 taacttttct tcatagttag ttagatttcc agtatcatca aacttaaagc ccattttctt
    15421 ttcttttaat ctatttttaa gtctgttact ttcagcttta tatccatctt gttgttgttt
    15481 tattaaatct ttttgttgag caaataattt attttgctcc tgtaagtatt taatcttctc
    15541 atcacctgta gcatgttcca tttttttgtc taatagagct atttcatttg ttactgctga
    15601 tatagcattt tctaactctt taaataattc tatgctatat tttacagatg agtctattgt
    15661 gtcattgttt attgtaactt taggtttgat tactttaaaa gctgatgtgg ctcttgatac
    15721 tgctcttgag aataaggatg gttttgttac aggagtttcg tcacttattg gtgctggttc
    15781 tgatgttcta ggttgggata gattagctgg aattggagtt ccattagtaa cagaggtacg
    15841 ttcagtttta ttggtcttat ctgaactatt tcctccacct ccaccaccag aactattggt
    15901 tactttatta gttacaaatg tagtagtgaa tgtttttcct gcatagtttg atttaaatga
    15961 ctctattttc ctaataagcc ctgatatgtt ctttgcagca gttgcagtta atgcactaaa
    16021 tgtagtcttt atagtttttc caccatatcg gctaacataa ctttgtactt tggctaacaa
    16081 acctgataca ttttttgctg cttgtgcagt ttcagttcta aatacaagtg tagatacttt
    16141 caaagctaag aattgtttta ctctagctat aagtcctgaa atattcttag ccccttgttc
    16201 agttgaagta ctaacattta tatgataatt accttgccca atttcttgtg ctttttgtga
    16261 taattgattt aactgttcag atgcttgttc tgcacctgta gcttcaatag taggagtggc
    16321 tttttcatta ttaagttcat ctaacttttg ttttgtattg tcaatttcat ctttaccaga
    16381 gttgtttatg gataactcaa taaccttagt tggatttgta ttttctataa aattggttgc
    16441 ctgttcaact tcagtttctc cttctgtctt tatttgtaca gttggagtta ctgttttatt
    16501 atctaactca tccatttttt gtttagtact gttaagtcct tcttcattgg taacttgagg
    16561 acttacaatt ggaatataag attcatttcc atattcatct aatattctca tgcactgaac
    16621 aactttttca ctattattaa cttgaggatt taaattagga gtgtatgttt tattcccatt
    16681 cttatctaat gtttctatgc attcaactac ttgtgattct ccatttactt ctgcatttac
    16741 taaaaggtca gctttagttc catctgcatt ttgaactgta ttaacagttt tctctgcatt
    16801 ttctcctcct tcaacttcta ttccaagttg tttttttatt tctggaggta aattgtttat
    16861 aaattcttgt acatttttag ctttttcaag ttggtctaaa ttgtttacta taaaatcaat
    16921 aacagcttcc tttttatcat ttggaacatt attaagaatt tcatctatct catttagttt
    16981 atctggattt ttattgatta tttcaaatat agtttctttt ttatttggag ctttatctat
    17041 taagttttgt aatgtgtcta atttatctat acctattact tctgtttcta tctttttttt
    17101 gagattatca ggtaaaatat catagacttt ttttgcttca gtcaatcctt ttttatctac
    17161 atctatatca tattttagac tcattggagc agatattttt tttctagctt cctctaaaga
    17221 atttacatct ttaaaagcat ctgcacaatc tgtagtaaaa gacaactttg tatcttcatt
    17281 tttaaatcta tccaactgtt cttttaatac actcaagtct ttttttgcga aatctagtcc
    17341 tttattatta atttcagtca caattttatc tgatttaaaa gtgtcttttt tgaatttttc
    17401 taattctttt aattcttttt tagctttttc tccattgaca ctaggagtga tttcaggggc
    17461 attgtctcct gtaaaagcat ttgcaaattg ctcatttaat gcttgaacca tatttcctgg
    17521 taatgcaggt aacttgtcac tgatttttag tccattttta agaatgtcat ctgttaattg
    17581 taatttaccc ttaaataagt catttaattg tttaacaaca tcattagata attgaccttc
    17641 gttttgcaac gtagttgtta cttgtagggc taattgagcc tgagcttcta tttgtgaatc
    17701 ttctccaaat gtgaatccat ttattatatc ttttagttgt tgtggtaaat cttgaccagc
    17761 ttctccactt tgtatatctt caagcagttt tatatttact ttaccattaa cttctaaatc
    17821 ttgagaaaaa tcatttaatg catcaaattg gtttttaagc tttattgcaa aactatcttt
    17881 gttttcaagt tcagctaaag atgaaccata acttttcaag aaagtatgta atttcatact
    17941 ggctaagtct aatccagaaa aaccttgttg taatccaata agccaagtat cagcacttat
    18001 acttccacca cttagctttt gaagttcatt cgccaaccct tgtaattctt tggtatattg
    18061 attcatatca ccggatgcct gataatttat attagcatca gttatcttct tattccactg
    18121 gtctaatttt tcaacaggaa ttgactcact tattttatca aaagcactta taatgctatt
    18181 ctgttgtcct acactatagt catgccaatt catattagct acaagctcat tcattttact
    18241 tttcttttgt tcagattgtt tagcatatgt tttagatata tcagaattag ttaatctatt
    18301 aatcgccctt ttctgcatta cctcttcttc ttcattatat ttttcatatt cagtaagaag
    18361 tttttgatga tgttctgcaa aatctgtttc ttgttgattg taagcctttt ttaatgcttc
    18421 tgtttgttct ttaaaattag atttacttaa agcattttta aataaattat gctcatcttc
    18481 aagaacttta tcaagttttt tcttttcttt atcaaggtct ttttttgtat ctggtgcagt
    18541 ctttgatgta gttattgcaa gttcatcttc ttgagacttt aaaagtttat ttttttcttc
    18601 tatagccttt cttaatttat taatgacctc atctaagtta ccactcatat ttagaatagg
    18661 gtcattattc tcatctacac ccaatactaa ttctggtgct atatctgcaa tttgttgttt
    18721 aagttcgcta aatctttcag tttcatcagc agtcttttcg gtcttactag ctaaattatt
    18781 gtactcttct gatatacctt ctaaactctt tttcttttgt tgcaaggagc ttatctcgct
    18841 tgtagtagtt ccaataactt ctttttgttt ttctgctaat ttttcatact tgtgaatagt
    18901 atcatctatc cattgtatac ctttagttat agcaaaagta gccaaaccta tcatagcccc
    18961 gtttaacaaa cttgtcgcta tatttaatgt tccaatacca atagaagtcc tagataaact
    19021 ttgtcttaat gctcccaaac ctgttcctgc tctagtaatt acatttgctc cattagcacc
    19081 agctacattt gctgccatta ctgcatgtct aaatgattgt agtattgtag ttgtagcttt
    19141 aataggagtt cctatcatat ttaaaggatt tataagtcta gccacatttc tagtaccatt
    19201 tgtcattccc ataccagaga ataacgtttt taaagtcata aaacttccta ttaatgctgg
    19261 tgttgttaat tttaatcttt ctaatgtttt tataacacta tttattccat tagatacaga
    19321 tattaaacca tctaaaaatc catatgttgt atttgaatta aatacagttt ggaatatatc
    19381 tgcccatatt gttttcaact catttaaacg ccctgcaaga ctatctaaat attgtttgtt
    19441 ttcagcctca gccgaaccaa attgtaaccc ttgtgaaaat tcacttctta tttctttaaa
    19501 agtctcataa ttacccatta aggattggaa tatagctgct tgttgcttac ctgctattgc
    19561 ttcagctaat cctttttgtt catcctctct gagttctccc catttgcctt tcaactcatc
    19621 taagagttga accatattct tcaattcacc agtatcttta tttttataaa tagttattcc
    19681 agctatttcc tttaaacctt ttgcggtttt atttaaagaa agtgtaccat catcagctga
    19741 aactttcata cctgctaaat ttattgcgac actttttaaa ccattaccta ctttttctgg
    19801 attttgtatc gcttcatttg ttgctgttat catacccact gtgtcaccta aactgacacc
    19861 atactcatga agtacactac ctccacgttt ccgtttatct tcaattaagt tcgctacact
    19921 taatccgttc tcttatgaac tgctatatgt ttccatacag acgagactat atcttcatcc
    19981 tataaggatg ctccccattt ccatatccaa tagcttgata tgtacggttt ataacctagt
    20041 cgttgaacct tactctattg agtcttggct gctgattgtc cctatctttt agattattac
    20101 acttagtact aaaagcctaa caggagtttc cagcagttaa aggagtttat cattatatat
    20161 tactatataa ggcgactaaa attaatcgct tcggcaacac ctgctgttcc aattgcataa
    20221 ttattccctg catagtttca aattgttatc ctacaagctt tttatcttgt agttcttaca
    20281 tttcttattc atgtaagttc agcatatatt ttcatcttca agattacttg ttaagatgga
    20341 ggacactcgt gggaaaatta tattctatac tattttaaac ataaaaatag cataggttca
    20401 tttcctatgc gttacggtga ttaaagtctt ttaattcttt aatttacctc ggtggtaaca
    20461 tctcagtctt caccgatttt gccccctcat aatattagat atttctatct aacacgccaa
    20521 acaatttagc atatccattg cagcagttaa ttctgttgtt ttctttgttg tattcccgac
    20581 ttgtacttgc atttctttaa gtggttctat tctaaatcca ttgattattg tgtttactgc
    20641 cgaagatgca ccttcaacat ccatatcacc tacattggca agtatcattg attgtcttgc
    20701 agcagcaata ctttcttgca tgcctccaat tcctgcttgt aaagaagatg ctattgattc
    20761 ttgaacttgt gatgcactca ttcctacatc tttagctgtt tgtattgctt tttctcttat
    20821 tctatctaac tcagatgtac tatccttttt aaggtcagtc atagagctat caagctctaa
    20881 tataacatct ttcatagacc taattccatc agtcaaagca tcgcccaaca tatctccaat
    20941 agaataagat gctacagatg aatagaaatc attaaaaaat cctccacctc ttgaaactgt
    21001 attatttaat ctttcagctt cttgtctagc atctctcatt tctcttgtta atctatcaaa
    21061 tatattgtta aaatcaccat ttagatttcc tgccgaacct tgaagttgct ctaaagaacg
    21121 tctaaaagct tcaactctct cattcccaaa tgcctgtcta atagaatctt ctattctgct
    21181 gaaattagac cttaagctat caactctttc tagatttcta acttcttgat ttatctcttg
    21241 tattctatta actatattac ctacatcaag atttaaatct atatttctac tagctgtctg
    21301 ttttaattct tgtaactcat tcctaagtct atttacttta tctgtatcta tattatcgcc
    21361 taatccatta agcctagcag atgcttgtgt tgccatatct tctattcttg aaagatttct
    21421 attcatatca gctaaatctc ttgttgctct tgaagcatca aacatatcca ttctagcttg
    21481 agatgatgaa ttcatttgtg catacactga atctaattgt ctttttaatc tttcaatttg
    21541 ttctgttgtt ctttcaattg aactatctcc tagacctgtt ctaatctgat tttgaagtct
    21601 agatacaaca tttgagattt ctttatattg tcttattaaa tcttgctgtt cattatttat
    21661 atttcctgtg tttccagagc caccaccaag taagctctct tgacttcttc tacttagttt
    21721 atttatttct ttcatagtag attcaatttg ctttaagttg ctcaaagcag tattatcaat
    21781 cttaaaggct ttattgaata tcccttttaa ttgctctgct tgttgtgata acttatctaa
    21841 ttcacctatt ttcaaattta atttaatagg tttatcttga ccactatttt ttaatttctc
    21901 tattttttct ctagcatctt tgtcatcaag ctcaatactg gttttaattt taaactcttc
    21961 aaccatttac tcaactcctt ttttgtataa aaaaaagaca gttcatatag aaactgtact
    22021 ttttctttat aaaaaatatt taagtttaaa tatttaagtt ctgacttatt cctttcaaca
    22081 tataatcata atactctatt atttcattat atttattttg taatattgtt ttttggaaat
    22141 cagatactcc gtctaaaata tttgactttt cttcttctaa tacacttttt aaatcagtaa
    22201 ttattttctt tttacttatt aagtcttctt tccaatcact tttcacaatt tcatagttat
    22261 tatatttttc agtaagtaat cttatttcat ctcctataat ttcactttga tttttagtgt
    22321 catttaaaaa ttgcaatttt ttattataaa tatcttcaga tgtactttct tcatctaact
    22381 tttcttctgt ttcttttttt actacttcat ttgtatcttc tttactatca ctacatccaa
    22441 taactccaaa tcctaacaaa ctaatcatta aaatcaataa tattttctta aacataatat
    22501 cccccctata ttctgataca ttaattatat caattctaaa ggaaaattta tactacaaaa
    22561 ggaaagtgac ctccaaatct ttattaataa gctaaacttg taaccacagt gtcttttgtt
    22621 gtcttacata tatcttctat agatttactt tctagctcag ttataccgta caaatcatat
    22681 acaaaagtat tgattgtatt ttcgcataca tttatatcgt atatgattct attaatagca
    22741 tctttgtact tattaaaata ttcctctaac tcatcaatat tcttaaaata aagcttcttt
    22801 tttttgctaa gttcattgta aaattcatca aaatctaata aataaaaatt atataattta
    22861 ttagatggat tattatctat gctcaatatc ttaaatacat ttttcaaaaa tttattagtg
    22921 tataagtata atttaccata tttatttatt agtattttac tattatttat aacaattgat
    22981 ttatcaacat tttttaaatt tggtattggt atatttttta ctgcatctgc tgtcaagttg
    23041 gtatttgatt ctccataaaa tttattataa aagtaattta ttaaactaga atttataact
    23101 cctatataaa aatatatatc ttccaaatta tcttctttaa ttaaatttat gatatttcca
    23161 ctagggaata ttatagtacc ttcaatatct actgttgcaa ttatcttatt ttgattttga
    23221 ccaactattc tttgtgttat tatcttaggt gatttgtgcc acctcatagt tttgtcatcc
    23281 atgttttcaa tatttacaaa tttatctact ttatcaatat agtatctatg tatatcctta
    23341 ccttccaaac atttatttaa aattccattt aattggttat tatcttttat atcattacta
    23401 cttaatattt tcttatcata tataattcca tcacaaattg ttttattagg gacactcatc
    23461 caacctttat gtaaatttaa ataatcccct aatttatgct tacatttgag catttttaat
    23521 attattgggt tgctttgtat aacaatttta ttatccaaat catttataat actttttata
    23581 gtaattttat tttcagagtt gtatgtatta ctattgaaaa tcttaatctt tttcatattt
    23641 tctttattta tacttataag atttatatta tttttaatat tcggcaattt tttattaatt
    23701 ataattatag cggtttcctt gtttacatcc tcaaaaggaa aaaatctata tggaaagtct
    23761 aaaatagtat caacacatac atttttaagt aaatattttc ttaaattttc aaagctttta
    23821 tttgtaaagt acgtattagg tgttataaat cccaaaaatc catcttgctt taatttattt
    23881 tcacaaaact catataaaaa caactcatac aaatccattt cgctaattag taaatcttta
    23941 tattttttcc aataatattc tctatgcttt tctggaatca ttttagttga aacatatggg
    24001 ggatttccaa ttataatatc aaaccctcct gacatcatta catcttcaaa ttcaacattc
    24061 caatcaaaag ctttagcaca atcaacctct ttgttatcaa taatagaatt tccacatttt
    24121 atattattat ctaagctagt taataaacta tacttgttag ctgttttaag ccataaagac
    24181 aatttagtta tttccacaga ttcttcattc aaatcaactc catataaatt attttttaat
    24241 atattagcat ctaagtcaaa aaatgatatc tcaccatcgg ttaaatcacg aagtatttcg
    24301 tttactgatt cagcttcttt ttttaacata gaaaaagcct cattcaaaaa agctccactt
    24361 ccacaagctg ggtctaaaat ttttatattt tttacaacgt ctctataatt tttccaaaag
    24421 tttatatatt tttgaatttt atcagtttta tattctacaa cttgtacacg cttatgctgt
    24481 atattcctac caaccacaac tgtttcataa tcttcttctt ttagttctgg aagtttatct
    24541 tcgcctaatt cttttttctt ctcatctaaa tatcttctta tggtgttatt aacaatatgt
    24601 ttcgttatat atttgggagt ataaaatatc ccatctttgt ttctcttact atcttttttc
    24661 ttaatattaa cttgatttat ttctagtttt agttcttcta agtcagatat agatttttca
    24721 aatatatgcc ctaatatatt ttcatttaaa tcactattaa aatcatataa agataacttg
    24781 tataaattct cgaaacattt atttggtatc tttagattat tcaaaatata atcttctgca
    24841 aataaacctc cattaaattg atttatgccc ttttcctgat tacctaaatc tatagattca
    24901 aacagaccct ttacttgttc ccagactcca aacctagata cacttttttt ccctacttga
    24961 atacatgttt caaagatatt ctctggtatt aatcctttat gttctgcaaa acaaacaaat
    25021 ataactctat ctaatatttt ttgtgtcttt gttaaacaag tttttacatc caaaatatct
    25081 ttattattta aaagtatatc attaaataaa tttaatctag tatttttata taggtcataa
    25141 aagccttttt ctatggcttc ctcttgcttt atattctctt cccaaagcat ctcaactcta
    25201 gattttccat gtttggtcat taaagattta gatgacaaaa gatataaaaa ttttttaaat
    25261 acatcatctt tttcatatat atctttaata gaaaaaaatt catactctgt agcatcatta
    25321 gcattataca atctaatttc cttgaagtta gagacaataa gccatgtgca atttcttcca
    25381 tatttaggca agtaagaaaa cccttgttct actggtgtat tatgattgtt ttttcttagt
    25441 tgttttgcat ctaaattagt tgttggtttt tttaattcta ttgctactct atagtcactt
    25501 tcttcattag aaaaatagcc tagtacaata tcagctcttg ttccatcaat cttagttttt
    25561 tcttctggtt ttatattata atccattata ttgtccgtaa gacttttata cctaagaact
    25621 ttgtttaaaa tatccgatac aaatatttcc ttaagttgaa tttcatttaa tttatcaata
    25681 gatttattat caattatatc tctccatttt tctaaaatta atcgtctttg tttatagtca
    25741 tataagtcta ggtctatttc catattatat ttttctttta atagtttttg attaaaaaga
    25801 tacttttcca tacaattccc ctaattctat ttaaatagtt tatattttta ttatatcaag
    25861 tgtaaatggt aaaatatacc aatttacact aaaatataaa atcattcatt agataaaaat
    25921 atatattatt tgtaataaat gttagataaa aggaatttat tcttggtaac acactaataa
    25981 aataataact atctgttata ataaactttt ttattctata caaaaaagac agctatataa
    26041 gctgccttaa tatttttaac tttttcatca atatgttttt caaggtgtca gatacatctt
    26101 tatatcctat tttttctact acatctttga ctacagatta aatctcatta tctatcattt
    26161 tttataaata ggtaaccctt aaacttaagg ctagttagaa gctacagaat ttaattcaca
    26221 tgataaacca ttccagtaaa tcatctaccc tcaagtagta gctcttcaat cctatcacac
    26281 tcaaagtagt gaccactcaa acatcaaaat aagctcttat ggtggctaaa caccaaacaa
    26341 aatgttcctc tcaggaacac ttgttgaaat tccaatactt tcaaccataa aaatcaacct
    26401 cctatattcg attctaagca ataaagatat atatgtcttt caatatttcc aagtgtctta
    26461 tatttgtcat acacatgtca tcattgaaat aactacaaca taaatgattc aatttaaaaa
    26521 acaatctaaa ttgattatct ttaatattta ttaatacatc ttgatattta tattacaata
    26581 gaataaacct tctattatta taagataata gaaggtttat tctatctcca caccttaaag
    26641 gtgtactatg gccactcgcc ttatctataa tattttaata ataataaacg tcttataaat
    26701 tttacaattt aatctctaaa acctatctta taacttatac attcatcatc tacaaaataa
    26761 attatatcat tgaacataaa gaagctataa tcatttttct ttgcctgatt agccattttt
    26821 attatatctc cagtccaaat atcatcatta taattatata ttaaatgttt tggaatattg
    26881 actttattat ttgtaaaact atcttttttt aattcttact tttctattat cttaccacaa
    26941 gattccctaa aatgtatatt aggataatct aattctcttg taacttctaa tacttcctcg
    27001 atatattcaa atttaaatgt taattgaaac aactatacct ctctctttat atcaatatgt
    27061 tatatacaag tatatttcac aatatacttg tatatatttt tgcatcaatc aatgtattag
    27121 aacattgaga aacaattcta aaccacttat ctaagcaaat caactaaact acctatctag
    27181 gctaaattac tcactatatg ttagagcatc accgcttttt aattttccac ttatgatata
    27241 catctactag tggataacat acaaccctta gaaaactcta taacttaata gacactcgat
    27301 attgtctatt ttactggcac gcctaattca ttcattttag acttaaaaca ctttggtact
    27361 ctctcttgtg ccttagaatt actttcctcc attatatttg ttctaggtct aaatacagga
    27421 ttatatttag tacttccatg tccccacaca cctccatttt caaatcgctc cattggaaaa
    27481 gcatgtgctt tgctatatat atcaaaccag ctcccactat ctttaatttc tgtagctaca
    27541 gaatctgatg ttatttcaga cacatctatt gcattaagta attcataagt tctatcataa
    27601 agtgatggag cgtaatcaga ataaacttgt ttgtttactt cttcttttac tatctctttc
    27661 atttcttttc caacttcagg catagatgca gcaatcttat tttttgtata agcaaccaat
    27721 tcatctaatg atttaaatac catctaattc actacctttt ctttaatatt attcattttt
    27781 tcaatttctt cagtctcttt taaaactctg tcctgtaata tctcattctt catctgacct
    27841 agcttaattt cagtattcat taataaagat gccgttaatt cattttctat ttgacctatg
    27901 taatacatca cattttctaa ttcactagat atattgccat ctactaaatc ttctatttca
    27961 atatttaact ctatattagt caatttatca atcaacattt taagaatatc ttcttgagac
    28021 aatgctaaat caggattctc cataccaacc catattttat ttaatatctc ttctttagtc
    28081 tccttatcag gatttctaac ttctatatat tcctctttac cattctcatc tataattggt
    28141 attatagccc taacttcatc ttgtattaat ttatctactt gtattttatt catatctatc
    28201 tctcccttat tttattattg gatatttaca cttaatagaa actttacagt ttccagtaaa
    28261 cttcaatata tttacacctc ttcttaacct aatccacttt ctattaacaa tattaaacct
    28321 attctcacca gaactattta aaacagtata gtataaatta tctattgtta ttttttcatt
    28381 taattctaat ccacttataa ctaaattgtc ttcttcatta tcgctgatag tagaatttct
    28441 aatagttata tctccttctt ttagacattc aatatcaatt actggagcat attcttcatc
    28501 tacattagac acattattta gtttaatttc ccttgtatcc ttgacagtta taactttttg
    28561 aaagcttcta taagcataat ttgtatatgg ttgaaactct atttctaata cgcctttttt
    28621 atcttttgta tatcttttta ttatttttct cgctttgaga tagtatattt cttctatatt
    28681 gtcataactg ataaaaggtt taaattctct ctgccaaaac caattacata tgttttctag
    28741 cgtatagtca tcccattcgt aagcctcccc atgttcgcta cacaaacaga attgtagtgt
    28801 tataggttca atagtagttt catcctctga gtaacaagga tttttattaa aagtactatc
    28861 agatttaatc gcttcttcgt agggcaatcc atattcattt agtatttcat catcacctaa
    28921 agtaactaat ttaatgttca tggattcact tgaaatatta tcaaataaaa acttatcatc
    28981 taaaaatacc actttatcac cttctttcat ttttttaagt tcaaatccga ttaaaaccag
    29041 atttaaacgt aaaaaaataa cccctactct tttgagtagg gaaattcact atttcttaga
    29101 tttaacatcc ttttcgtcta ttaattcagc acctaacata gaagccattc taacagggct
    29161 aacatcttca tctccaacaa aagcgaatac tacatattct ttattttcat ctggcaaaac
    29221 atctagtgtc atattaaatc cagatggatt ctcagcagta agatttaatt ctatacttct
    29281 ttgtgccttt gcatttggta tagtcatata taagaccata tattcaccat cagcagtttt
    29341 agccataaca tctgcttcta ttacatagtt tggagcagta gactcttctt ttatttttat
    29401 aacttttgcc tttggtaatt cctctaagta aaacactgct actttatctc ctgcattaaa
    29461 atcagctgta gatattgtta tttctgtgtt agagcctgtt acagttgaag taaactgtaa
    29521 tttcttaact aaagatatac catctttttc aacactatat gcagatatac tattagtaac
    29581 tggttttaca ttttctaaag taactttctt agtaccatca gaagttagta attttctttt
    29641 accaacctta gccgattctt caaccatatc agaagctaat agcattgcta gttgtggcat
    29701 ttgtattacc tcttgttcaa gtgctaaact tgctgttata gctccatcaa atgctattgt
    29761 gtttgcacct ttagcttttg cgtacacgct ttctgaatct aatttgaaat taaaagcatt
    29821 taaatctgct gtataaaaaa gtggttctcc agttgtttta ttttttacta ttatattact
    29881 tgcatctttt atcgcaaatc tcattatttc atcatcctct cattttttgc ataaaaaata
    29941 acactgttat ttaacagtgc tagtttgtat ttttatttct ttagaccaat gtttaatctt
    30001 gtctgcctca acttgatatt taaaagacat tgcaaagcct aaactttcat cataattttt
    30061 aaattgtatc ttagtcttat aagcattaat taattgccaa taagtcattt ttagaataac
    30121 atctattggt acatatccat ctatgttttg aactacattt atataatcac ataagtgata
    30181 tgcttctttt tctcttttct ttctttcctt ctctttaaag tgtgcaatca actgtttttc
    30241 tctttcagag ccagtatttt caatccactt atcttcatca tctttaaata aattcttttt
    30301 atcaatacaa aacatctcta aaatcaaatc tgataccagt ccaaaatcct ctctacttat
    30361 aaaagcattt ttctttttat catcaaattt aattaaaata ccaattttaa tattattcat
    30421 atactcaata tttttaatat cagttttata taatatagat aaagattttt ttatcttatc
    30481 actaagtaac tcaatttctt cagaagaatc caagataggt atagcatcat atttacattt
    30541 caattcaaat attttctcgt tacatagctg agaatagctc ttttcaagta ctaaaaatgg
    30601 attaactatc tctaaattag ccatatcaaa tttaataagt tcttcaatag taggttgata
    30661 tacagttcct aatgtttcac ctagtttaat tggtaatcct gtgatataat aattttccaa
    30721 cattacatat caccaaaact ttcagctgat acagttataa caaatccgtt ataatcagta
    30781 tttaaattat acatttgata tacattttct aacttaatct tacctatacc agctatttcc
    30841 tcattttgag ttacaatatc aactatacaa catactaatg caacatctct taagccattt
    30901 gctgtacttt ggcattcatc atgacaaaca acaccaattt ctatctttgt ttttttaatt
    30961 gtcctacttc cttcaaagca tggcctatat tctgacatta ttataaaaac tgaaatatct
    31021 gcttctttta atactttttc tactcttcta tttagaaata cttttttgtt tctaagttct
    31081 ttaacaggat tttttatatc aggcatggat aaaatatctt tttgggattc atcattataa
    31141 atcataaatt tagcgaagtc ttgatttgac attagagttg ctcctatatt acttatcatc
    31201 ttgttaggga aagccatata aacccatata tctaccccct tagtgttatt tttttagtat
    31261 ctattgtttt atttgtatct ttatctttag ccaatagcaa ggcttcaaag ccagaatatt
    31321 tagccaatgt attagcctgt atgacacatt ttttctcatc ttgattaatt atattacaat
    31381 atccgtattg cttgtctaag agccattcaa ctccttgaga atggtctatt ttgtattcat
    31441 tttcttcgcc tagattaata aatccatcac ccataatttt actaaaagga ataatcacac
    31501 tctcattttc agataaatca ttccaagcaa tattatttat tgtatcatct tttgaaatca
    31561 atgcatcttg taaacaaata gctttaataa gaccatctgc ccctgtttct ctgccattat
    31621 actcaaagtc attaatacta gtaactctaa atacagtttt accagttaac attattctag
    31681 tgtcaatatc tatagtttta gtgacaggat tacttccaaa ataaagctgt ctttttgtat
    31741 ctgagataga agtatattta ttatctgcca taccatcaga atataaggtt aaattttcaa
    31801 cagctatagg gattttatac atctgacctt tatatttata attaaagaat tgattgcatc
    31861 tttttattat gaaatgttta tatgtatcca tttctttatg ttctttaaat atagttaacc
    31921 aataacaatt atcatagaaa agataacaac ccacatctac atctaaatca gattcaacta
    31981 atagattttt ttcatctaaa gctcttttat cattattagt tatatcatta attgcaacta
    32041 tagctctttt agtatcttct gttatacaaa tttcatctat atcagttatt ggtacttcaa
    32101 tacaggttgg tgtttctttt agatatttct taaaacttaa tctaagttgt aatattcttt
    32161 tttctttagg agttgaacaa ccaagtccaa ttcttttttt tgtatcactt aagtaactca
    32221 tgctagttcc atccttcaaa attttttagc atgtatcttt gttgatattt attaaatcta
    32281 gttctcaatt gctcttctct tgcttgaagt ttagccaaca tattagcacc tgatttagca
    32341 ttataatcag aatcagttag catctgtttt aaattttctt ctctatttat cttaggttgt
    32401 aaccaatgta tttgcatacc atatgataat attttaattt catctaaatc taaatcagat
    32461 actatttctc ctaaatattt gtatttgaaa attatctctt ctgtagtttc tacaacaaaa
    32521 cttattataa atttttcatc ttcaaagctt attgtataat ctttatctaa ttcgtattct
    32581 tcttttgtat cttttcccat caaagttatc tctgcatttt tattactata attagatgta
    32641 taacttaatt gagcagcagg aataatttct ccaccttttt catcaacata ttttatagtc
    32701 aaatcttttt tacattgatt aaaatcaact atagcatctt ctaaataact gtacatcatt
    32761 ttttctatta tttcatttga tagtaataac atctcttcat cattaatacc atccaaaaac
    32821 tttttatata tttttacaag tggtgtaccc aaatattcca ccacctttaa ctaaacaagt
    32881 acaaatcttc cattccaatt cttttagcta atagtttagc ctttagccca gaatcaaact
    32941 ttttcttttt atgtaaatct attgccctct cagctaatct tcttgttaac tcaacattat
    33001 ttttatttaa tattttttca aaagaattta tatcaacttt atcagataag aaatattcta
    33061 aatagtcttc attaggattt cttatatatt catataaact attcaatcct agaaaatcta
    33121 ttatgtccat tggagtacat tcaacatcta aagaatctac atccgaaatt attaatctat
    33181 gttcttcaaa aaaacctgga cttcttctta ctattctata aagagtatct aaatctataa
    33241 attcagttga atcttttgaa cctactttag ataaagaaaa aatctgttgt ttttctcttg
    33301 ggtcaatata atcaacatcc catgtggata tattttttat ttctatatct atttcctgtt
    33361 ttttttgttt tagttttctt tgtagttcta atctatttaa tctagcttct tttttattta
    33421 aagtagactt tatatctttt tctaaagtat taactttgac ttctgtttta gaaatatttt
    33481 cttttttagc tcttgccata ataatctccc tcccataaaa aaaagaaggt ggataaccac
    33541 cttctaattc aattattgta ttttataaac tccaaattta gcagcagtta caactcctaa
    33601 atgtattttt tgagccataa aatattctat ttgttggtca tctctttctt tttcatcagt
    33661 attttctatg accaatacat ctccttcagt accaagtttg attatcttct ctccatcagg
    33721 tattacatag atagccttat tatctaaagc ccactcttta ccttctgctg cattttcatc
    33781 ataagcattt ggtaaactaa gtactttata tccacctcta aatgtttgta taaaaccata
    33841 ttttcttttt tcttcttttt ctaaatcagt ttgaacacct tctaaattac ttaatgcaag
    33901 tggagtacca tatataatag gctttttacc agtagcccct tctaccttag ctatcaattc
    33961 caataatact ttgtctgaat tacctgtagc ttgaaactta gcatttattg ttgaatatgc
    34021 accttcaaat gtcttcgcta ttcttctagc aatatcataa tgatatgaat ctgataccct
    34081 attcacaaat acaacccaat ttattcttcc tgttataaat ctctctgctt cttcatatat
    34141 agcaacagat aatttaaatg ctgttgtagg aactttttta ttaagtaatc tttgtcttct
    34201 tgtactatta acaccatctg ctatatttgc aactttaaat aaattagtat tttcaacagt
    34261 aaattctttt ttatctccta aatcaaagtt ctcaaaatca caaaacggac taaatacttc
    34321 ctcatttaat ctattaatat catcagatat taattctgat attaaattat aaaatcccca
    34381 tttattttct tggaatttat aataattata tttttctcct cccatcattt cttttaattt
    34441 attctttatt gcactttcag catctctata tgttattgtg tttccatctc tatctgtata
    34501 ttctctaaat gtatctgtat atagctcatg agctattctc tttaaagttt ttgctgttgc
    34561 cattaattta cacacttcct tttctatttt tttgcataaa aaaataacag ttatagactg
    34621 ttatctcctg tttgttaatt ttatttgatt ttataaaact tttattgtaa ccgaatcttg
    34681 accttcatag ttccataatt ctaatacttc tgctactgga gttttagcat ctgctgtagg
    34741 caatttttca aactgaaacg aatcagattt taattgtaac ttgtctttta ctgcaatact
    34801 tttatctgct atatgtaata gagatatagt tacctcatct ccttttttta gtcgtctaca
    34861 tctacatatc tgaccaggag aaacttcgta atctctttca tctaatcttt catcatacat
    34921 agttgctggg tcatcaacta taccccaatc taatgtgtca tttgtaactt tatatatttt
    34981 atgggtatcc ctaccatact ccgtgtcttc aagttctcca atatttatta cagcaccatt
    35041 ttctaaattt attggattgg tatcctctga tggaacaaca tatttacctg ttaaaacatc
    35101 aggatttttt actttatctg tttgtattat tgctttatct ttcttcatgt aaattcctcc
    35161 tattattctt tatctgaata tttttttata aaagatattt cttctggttc actaaaacta
    35221 tcattattat tacttatagg tatttttatc gtattatttt tatcatcatt tatactaaaa
    35281 ttttcctttt cgctttgttt attgctaaga gtttttaatg caaatatgta acccaattct
    35341 ttcttgtatt catctaatgt aatttcctta ttataagctt ttatttttat atctttaatt
    35401 tcatcttctg ctaattcaaa tttttgagct acatcatcaa ctttagattt aaataactca
    35461 aattcttttt cttctttgaa tgcctgtaat ggctctaaac tggcttttaa attagatatt
    35521 tctttttgct tttcagtaaa tttctctatt atttcttttt ttaatttttc ttgtctacta
    35581 aaaacctgta ctatttctcc ttcttgtttt tccctccaag tttgtatata tgatttttta
    35641 ttttcataat ccaaaatgac agcatcttca ttaactatat atggaatacc ataataatac
    35701 ccccagttaa tttcatcttc aactatagca atattctctt ctggtattaa atcattataa
    35761 taaaaagctt gtacttcaac tttttcacca taccaattct cagtttcgac tttgtattct
    35821 tttaacttat ttcttatttc agtactaaga ttactcactg ctaaagcata tccttcagaa
    35881 tttttattaa gtttttgatt cttatttggc aaattctttt ccccctctcc atgttctaat
    35941 gcataaattt ctgagcatat ttttgatatt tcttctttat aattaatttt tcttgaaaat
    36001 ttagttaaac aacaatttga acccatagct ccctttacat cagaaccaag acatgtaatt
    36061 ccatgatata catagtcttt tatattataa aatccatctg aatcatctaa ttgataatca
    36121 tttatatcta tttccattga aatttctatt tcatcagaat ccataattat atcgtaagca
    36181 tgattgctat atgatttata tatatatcct ttacatttaa catacttctg cccatcaatt
    36241 tcaacttttt catatttatt tgtttctggt ataacgccaa ttattcgttc ttcataatat
    36301 tcttctaata taaacccttc atctgtttga actacttgtg ttaaaacatt atgaccatca
    36361 aagtcatatt ttccatcttc atttattttt acatatccta gaattggaac attttttaat
    36421 gttggttcag ctttatcaat agcttcttca taaaatttag ttccatttgg atttgtacct
    36481 tcatgcataa catagatata cactggcaaa agattactat ttagttcttc caattttttt
    36541 ttatctgaat aatgttttaa attacaaggt aattttaata tttttatttt tttcacctcc
    36601 ttttaaaaac gtattttgct agtaaatata aatcttttca tttcttcatt actgaaatta
    36661 tttattaatt ttgatttatt ttcaaaaaca tataaagtct tattattcaa cttgttttca
    36721 catataaaac gatatccttt ttccattaat aatttcttat catcttcaga aaaagcatat
    36781 ataaacttac tcataattaa tcattctccc catttccttt tgcttgagta gaattaccat
    36841 tatctgtccc tatatcagat ttatctggtc taccactgct ttgagtatga gatgtttgtt
    36901 gaggtattaa aaactcatca aatcccatta atttttctgc ttgtaaagtg tttatagctt
    36961 gaagtggagt aaacccagta cttgcaataa acaagctttt actccctccg tatcccatat
    37021 cttctcgata ctgtttggat aaattcattt tattaaagtg agtagttcca ataaacttca
    37081 tattaaataa atttgccttc ttgtctttat ttagttcaaa gttaacccaa ttttctatca
    37141 tttgttgaat cctcatagga attaagctat ctgcaataat accatttaag atagattcat
    37201 tatttatctt gtcagagtta agtaaggctg tatttattcc agcgttatca aatatgaact
    37261 cttttgcttc ttttacataa tcatttattt tagattttcc atctgaaaga gtatgtgttt
    37321 ccaactctaa aggatttgta gttattgctg ttccttttgg taaatttgct tttgttgaat
    37381 tgtggtatat gggaattaaa ttaaggtcta ctagtggttc atcatttttg ccaaatggta
    37441 tcttttgatg tattaattta atactttcta ttactgcatt tgtgcttttt aaatctttca
    37501 tatcttcaag ctccattaaa tcgtcaaata taaagcaaaa aaatggaact cctttcactg
    37561 aatctaaatc ataattaaat gctactgctt tatcacttaa ttgaaaatat gtattatcaa
    37621 ttaattcttc tcgtgtaagt aaattagatt tatatttttt atatatgttt ttaatttctt
    37681 ctggaaagga tattatgttt ttgtcagtaa gtttttttat atttatagcg tatctcatta
    37741 cattattttc tatcattgtt atcatacaaa attttgctgg tatctgttgt aaaaccatcc
    37801 ctgaattatc ttctatctta tataaataaa cctctcctaa ttccaatact ttttcggtta
    37861 tccaagctga tgtaaatttt atattatatt tttctaattg actcgccgaa ttcatatatg
    37921 cttttgttat tttttctttt gtttttaatc tacttatgtc ttttgggtat aaaatatggt
    37981 caaaagtatt catattagat attaaattta aaactcttct atatgtacca gatgtagctt
    38041 ttaatatcat acttgcatcc tgaagtatat ctgtatttga aatttgatat ggattggaga
    38101 gagcttttct taatttgtct ctgcttatac ttcttaactt atacatttct gttgctaatg
    38161 ttgtggattc ttttactgag gcatattttc caatttgagc atttagcata ttgatttgat
    38221 tttgtgtaga attgttgtct ttagacttgc ttttattatt attttttttg cccacttatt
    38281 cacctcatct cttaccaata aatcataaca gttttttgat tatttctatt ttttcttttc
    38341 tctttttctt ccagataatc tgctaagaaa ttcgtataag ccaaactaga atatctatct
    38401 tttcttgctc cacttttttc ctttatttta atttttcctc catcagcact atattctaaa
    38461 tttattaact cattcactaa agccgttgtt tgaagataag gggcaatata ttttgcttct
    38521 aattctgcct ttttatctat ttcatctgcc tttatcattt ctttttctaa tatcatttct
    38581 tttgcttcaa tatcacttat aggaagttct aaggttctat ttgtaaggac atctcttaaa
    38641 gacatagcca ttttatgatt ttcatcagcg taagctttca tggaatatac aacaggaagt
    38701 gatttttttg ctagtgactt gtcaacagta ttatcttcat taaaacatgt gtaagcatca
    38761 taccattcat ctctatctga atcataattt gctttctgta tatagctcca tacagttgtt
    38821 cctatacctt gtgtatctaa tatcatataa tctgcctgaa aatctgaaaa taattgtttt
    38881 aatcttattg cttgtttttc agcttccata ccattataag cttctatatg gacaacacat
    38941 cttttatatg tgccttcatt tggaagcatc ctcatcaaag tataaataga attatcattc
    39001 ttaactcctc tggccaaagc tatatctgca ccaataatcc gtatttctcc ttttatctta
    39061 ttaagatgat atttcttatc tctttttttc ttattttcaa gatactctat atcactagga
    39121 ggataaaaca tactttctaa taccctacat ggattcaccc aagatgactt gaagaaagca
    39181 tcatctgatt cattataaaa cactccacaa tactccatca tgaaagaagc atcactcata
    39241 ctctcttttt tcatttcttt aagtattctt tttttagtta atagtccatg ttctaaagag
    39301 caagtgaatg gaatactaca tgcaaacata tcttcaccac taagcatacc ttttactgtt
    39361 tccataaact ttttataact ccaatgctga gaataccagc ctgaactaag ataaatttct
    39421 ttattctctt cttgcatata tctatattta ggattctgta aataccctgg ttgtcttggg
    39481 tttgttaaaa atggaactaa aacatcattc acagttcctt catccaccat tctatattca
    39541 tcaacaataa gaacattagc tctgtaacct cttgcatcat cattagatac aacagcttct
    39601 attctacttc cattccaaaa atctatagat acttcttgtg catttacttg gaaactttta
    39661 atttctcttt tcagagtatc tgattttaaa tataaatcac ctaaaatttt acttgtaata
    39721 agtaattttg cttgtttctt tctttttgct gctattaaaa cacaagtacc tggttttaat
    39781 acagctataa cacaacaaaa cactcctaga agccatgatt ttcccagtcc acgagaagca
    39841 ataaatacaa attggtcaga cttcatcatc atataaatta atatctgttg aaataaatgt
    39901 agattaaatc caaagtaatc catacagaat ctatgtggat ttgcgagata aaaagcaccc
    39961 caatactctc ctatactctc tagtagattt cgggatgaat cattagatga cagctctctt
    40021 ttttcatatt tagtcctcat ttttattacc ttctaaaatg tctcttacat catctttaaa
    40081 tttaatatct ttatcgccat catttatcga atacttacct gtagctaaac ctaatgcaac
    40141 agcaagtggt tttttcatat gtttatttac ataagcttca aatccatcta catcttcata
    40201 ttcctttaac ctatccttta caggttgatt tttttcatat atcatcattt tcattccaaa
    40261 tgtatcatct tgcgaatctc cagctttctt tttctgacta ggctttattt cagcatcttg
    40321 cattttactt gatactaatt tagataaatc attaaaagct ttcatatctc ccttttctct
    40381 tgatttatct ttttctaatt caataataca aatctcttca aacaattttc tttcagttaa
    40441 tgactctggt tcataatatt ctttatattc cttatatttt ctttctaaga ttttatactc
    40501 ataatcatca aaacctcttc cccattttaa tttaatttca tcatttatga ctatattttt
    40561 atcattatta tttcctgtat atatttcttt caataaatta tctaaagatg tctttccctt
    40621 atattttgaa tttctattaa taattttcat atattcatct attaattcat ctttattttt
    40681 tttatctgca agttctttag ctaatttttc atcaaaataa acatcaaagt tgaaacatat
    40741 atgttttagt gcctttacaa gttctccatt gtaacaccca tttaatagta aaaacctagc
    40801 tctaaaacat tctttgcata ctggaagtct tttatttaaa gtaaatattt cactatgact
    40861 tttccaaaaa tatctatctg tatatttttc ttcaccacaa ttcaaacact ttgttttact
    40921 aattgccatt cataacatca ccaccattaa aaaagaccac tagagaatta aatctctagt
    40981 ggttaatagg gagattcaac tcaattaaga gctgaattaa atttacaata taaacttaac
    41041 tcagctctta ataaataact tatagcttac ttaaatttat attgtaagta catattctcc
    41101 cactttcatt aaatatcatt aatttttgca ttgcgtgtga acttaatctt agattcttag
    41161 cataagaatc cgttccggag aaacttccat ttacacatat ttcactttct ccataattat
    41221 cttccttaca attgtgtaga tgagccataa agatataatc aggaattaat tttataagag
    41281 aggtcagttt aggaattgct gtagacattt tatctttgtc tccatgcact ccaaaacaag
    41341 tatttccaca tattttagcc actattatgt cattatcata tatattttct tgaaatataa
    41401 cattgtttat atttttaatt cttagcttta tatattcatc tattaataat gtaaaattat
    41461 ctttatctaa attttcatct tttttaggaa gaactctatc atggtttcca cctactgaat
    41521 aaataataat tttatcaatt tctttagata actcatatat aaattcacta agtatttcag
    41581 acacctctat aatttgttca actatatttt ctctattttc taatcttata gaattatgta
    41641 tgtatccaga aattaaatct ccaagtaaca ttacatgcag tctcttaact ttatgtaact
    41701 tactatattc aataatttta tcttttaaat attgtattct tatcttgaat atttttgaat
    41761 tatatctatt aaatgcatta atagtctcta atccataatg tatgtctgaa attagcataa
    41821 tagcctcttg atttgaagat tcatagcatt tgtaactaga atcacttaga aatggcttat
    41881 gaagtgatat atcatctatt ttattattaa ataaatcaat tatattatct attcttgaat
    41941 attctcttat tttcttattt actaatgacc tttcatcaga tagttgtact tttatctttt
    42001 ttaattctaa tattttctca tttattttat caatctcttc ttgagtagaa ttattctgta
    42061 tcttagaatt aagataatca aaagcctctt tcaacccata ggaaaccttc ctacaatggt
    42121 ctggagaaca ttctaacccc aatagttcaa ctatctctcc ccaatccaaa tctatctctt
    42181 tattaacctt tgctagtcgt attctaatcc tatagtcaac tagtgactca tcttcttttt
    42241 tcttcaatat gtcttccata tttaatatct ccctatttat cacataaata tcattatcaa
    42301 tgtattaagt aaaaaataaa tagtccaata ttgatttatt ggactattgt ttcacttaat
    42361 cttatcgtta tgtttaaatc tgtatcacca gtatacttat ccaaaacatc actaagtaat
    42421 acttcatggt ctccatcttt caaatgttct ataattttat atgtattatt ttcttgtttt
    42481 attatttcac atttttctaa tactgttcct ttattatttt tcatgcactt tcaccttttt
    42541 tataatttta ttaactctac tgggaatata tttatttgca aattaggcag ccttgtagct
    42601 aacaatagct aatataagtt aacgcattta gcatttatca aggattttct ataacttttt
    42661 tattttattt ttactatttt aataatttaa tcttttatcc ttgagatttt atatttgaat
    42721 ttttaacttt aagctttata tctattgttc tcttttatac agtacaatcg tttcgtttgt
    42781 atgtacccat cacttttata taagcagttt gatttttaac ccaaaaccaa atgggaactt
    42841 ataatttatg ttattcgcct aacctgcaaa ttaaaaaata gtccaattaa ggactatctt
    42901 aaatctacat ctataattgt aagtgcattt gatgtactca atgcaaaatc aacttctttt
    42961 tcaaattctt ctatttcatc ccttaatttt tctattttct ctcttacttt taaagggtct
    43021 actaaagacc attcttgttg ttttttataa aatgaaataa gttctgctcc atctttactt
    43081 ttttcttttt cctcaaacat tctgtctgta tttttttgca cttcttcatt tctacgattt
    43141 acttcagaca tcatacaatc atagttacta accatttgtc tcaacaagga tttatctaat
    43201 tctatactat tttttctttt tattgcttct aaaactgtat aatttttatt actaatttga
    43261 acatttgtta tagcattaga gatattaatt gctttatcta atgcgttata attatatatt
    43321 aaatcttcta tttgttggta tttacttgaa acttctacat taaaatcttc tacacttgtt
    43381 tttgtttcat atacattttt atcagaccct tttttagttc ctacaatttt aaaattatta
    43441 atgcatctat ctattttatc ttctaataac ttcttttctg ctaaagcctt gtgtacatta
    43501 tatttaacca taaaaacatc tcccttttaa ttaaaatatt atttaaaaat aacaaactct
    43561 ttttattgga agagaggaag ggatttgaac cctcgtatca aattaattga actaatagtt
    43621 tagcaaacta tcctctttac cgcttgagta cctctccata tttgctagga ataataggag
    43681 tcgaacctat gacctttcgg gtataaaccg aatgctctaa ccacctgagc tatatccctt
    43741 ttgaaaacaa atttaaatta tattaccaat ttaaaatcta tatcattttc ctctaaccag
    43801 cttttagcta tcttttccat ctttaagatt tcttcatctg aaaatctagc taatccttta
    43861 ccttttcgat ttctaacatt aatgccaagt ttatagttaa taaatctata aaattcatcc
    43921 catgctttac caaacataca attaaatttt ttaactgcta ttgttctaac acatttatta
    43981 ataatagctt tactttctgt tatagtgact gaattagtta taacatcttc taaatgagat
    44041 attcttttat tcttcaaccc tattaattct gtctgtagta cagataattt attatggtca
    44101 ccagaaatta tcgcttcaag catgtcttct tttatatttt gttcatttct aatttcttct
    44161 attacaattt cagtttgttc ttctgcatca tgtacaatat ctagtaatct agttctaact
    44221 tctttagcaa cttctgaatc tctaagtaac atgcctattc taagaatagc tcttttaggt
    44281 attaatatta gacctcttgg aggaatttta aaagtgacat ccagtccctt tttagtattt
    44341 tcaagtactt cagctatatc attgtattta tataacttaa gaccatctaa ttctaattca
    44401 attctatttc tctgtataag tttttttatt gtatctctat ctacttcata atactcagaa
    44461 acaagttcta ctgtactaaa atctgtattt gctaaagtta atatctcttt cacatgttcc
    44521 aatacatcta ctctatctat atttctatct cttaattctt tattttctat aagtttttca
    44581 ccattcattt tatcaaatct cccttttagt atttatttaa aaggaagaaa gacttactgc
    44641 tatctcacga catgtgcttt cttccagttt tgaaatggtg agtaattatc ccacaaattt
    44701 cacgttgtag tttaatattt ttagtggcat catcatctta caatataaga tacctattac
    44761 cagccactag agcttctcaa aatgagctat ctctgctaat tgtattaatt tttagcatat
    44821 tctaggtttg ctaccatatg tcaccatatg aaagggcttt taacccatac gctctctata
    44881 taattgcatc ttttaaagat ttagctattt ttaattttgg aactcttttt tcctcagttt
    44941 tccaaggttt tttagttcca tctttaagag ttatttctcc ttctttacct ttttgtattt
    45001 tagttaggta tttaactccc atcaacgtca attcttcacc atcttgtagt acttcgtttc
    45061 tttttttttc tatcacatca agtatctctc ttactcttat ctgtgataca cctaattctt
    45121 ctgctacttc ttttaaaaaa tctacttttt tcatatcttc ttaatctccc ttttcttata
    45181 taattttcat ttgataatag taaggaataa ttttattatt tttattaacc ccttacataa
    45241 gtaatatgtt ttaagcgacc cttttttaaa ccacttttcc ccaccagcta attacagttt
    45301 ttacaatttg agcgatatcc ctttttacca tttttatcaa acctagatag caacttaatt
    45361 tttccacatc tgctacattt tttatatttt cctttacaaa cagatatata ataataattt
    45421 tcttcatagt ttttctcata tgcatctatt attttgttca ctattttatt tatttgatta
    45481 tttattgctt gaggagttat attcattaaa tttgaaataa actctaatga tttatctttt
    45541 ctatataaat ttaaaatatc tttttgtact gtggtaaatt caattttaga tataatatta
    45601 tttaaatcca taactataca tgttaaatca tcttgcaaat cattaccctt ttgaatcctt
    45661 aaaagctctt taacatgtga tttatcaaac atatctaaat agtcccattc tgggcttcct
    45721 gcatctgcta atggtgcttt ccatataatt ggtctctcta tagaattttt aacatcagtc
    45781 atatcatttt ttaatgcatt taaatttttc ctaaccattc tcttaagttt taactcttct
    45841 ttacttaatt gtttatgtcc taattcttta tatttagctt tataccattc ataagtatct
    45901 gagtatgttt ttataattgg atatttttta atatctttag gtttaacttt tatatctttt
    45961 atttttttat agtttttagg taattgaaaa aatgcaaagg aattgtcttc taggaatcca
    46021 tctttattag aagtgtttga atttatattt ccaccatttg caggtgctat tttatttaga
    46081 agtgcttctt cctgacatgc tctattaaat aactcttttg aattgtatat tcttatttta
    46141 gtttccttag gtttatcatc tactgagagt atatagctcc ccattatttc taatgttttt
    46201 gctatattag aagtagaata tatactgtca tctttattta atatcaactt aattttcgat
    46261 gtattatgat gtgtgtactc ccatgtacca ttactattac taaaaggatt tttaacattt
    46321 atatattcga ttggattaat ttgattatag ccacaccaag taatgaatct attataatcc
    46381 ataactactt cttctccatc aatagtaaca taatatacac catctttatc taaaggacta
    46441 tctgatgttt gctcaaatat attttcccaa aatttatcat tgaattgttt tttttcttga
    46501 tatttcactc tagtaataat attctcattt ctctttgtaa gagtattata aaatgtatct
    46561 atataatttc tatttgactc ttcaaaccac gtgtgtttta cccctaatcg ttcctctatg
    46621 tatttaattc tatctttgct attgtctatg ctataatcta aattctttat gtaatcttgt
    46681 gcagatttgc catctatttc ttcataaaaa ttgttattat tatatatcaa tattatacct
    46741 cctttccttg caatccatca tcataatctg tatcatcata atcccatagt tcatccttaa
    46801 aatcctcctt atgcctttca tttacaatat catatgaaga ccttttactc atctctgtgt
    46861 atgtatctat catttgttca tattcctcat ttaatatttg atacctattt ttatgtacgc
    46921 ctgttttctc tgattcatct aaatcttcta aatatattaa ttctattttt ttctctttca
    46981 tacttctcct tttctatatt ataagatttt aaattaattt tcttggtcac atttctgtgc
    47041 cgtttttttg ccttttggtc acatttctgt gccaccccta aatttaattt tttaactgtt
    47101 tttcctatat ttttgttaat ttttacagtt cattacctct tattcttaga cagactttct
    47161 aaatacaatt aaaaaagcat aaatcaattg ttttctttgc taaatttaaa ttatttccct
    47221 tccatattac acaaggattt ataatgaaat agtctgtatt tttgttattc ccttcaacga
    47281 ttacatattt aaaaaaataa tatttatcat cttctacctt tatataaaat ctaagtaatt
    47341 cctttttaaa tttgttcata tcttgtttta ttgtactaat atttaataat tgacaaattt
    47401 tatataaact aatttttttt atttttgaaa tatctgtttc atgagggttt aaacataaga
    47461 tattactctc gaaatgtata tatggtatga gttgatatat ataacttaat tgtttatgtt
    47521 gtcttggtgt gcaatgttca aaaagaaatc tactagtatt tatatatatt cttgtatatt
    47581 ctttattttc aaaattagga attcctttag taaaatactt tggatttata taaaatttat
    47641 tattagattc atataataat tcacattttt ttacgtctgc taaaaaattt ctaaatgccc
    47701 tatctttaag atttaatatt tctctcatgt tttttctatc tataggaatc atttctttaa
    47761 actgagaata tctaaccaat aaattttctt ctcctgtatt atagtttaga tatgttgcga
    47821 gatatattaa tctacttata ttagctttac ttatatttac ttcattaaat aataattcat
    47881 ttttaacata agtacaaaat acaaaacctc ctaatttaaa attatggtat ggtaattctt
    47941 ttttattatt gataatagcc ctttgctctg gagaaaaact cttttttctc tttccaattt
    48001 caagtacctc acctcttttc atccctttat gctccaatat ttctcctgtt cttttgtctg
    48061 ttacaataac atcttttata aattcattac ctctaactat aaatatctac ctcttttctt
    48121 ataaatttta tttcaattac aagataaaaa tcatcttgca attgttcttc gcaacatgtt
    48181 gcttcagaaa tttcattacc ctctatgttc tatttctatt atatcatata ccctctatgt
    48241 tctcaatatt ttttttaata tctacccaaa atttcttgag tagatatttt cttttaatct
    48301 ggcatattat taaatatatt cttaataata ggattttctc tttttatatc ttttttttct
    48361 tcagtaacat ttgtcttttt atttgtccta tatacaccat tgcctaaaca ttgttttaat
    48421 aatttatttt cttcttgaag atttttccac tctaatatta ttctttccaa agctgtattt
    48481 ctactgctta tatttttatc attttgatac ttttctattt caccaaatat atcttcttct
    48541 aaataaaagc tagatgattt tttcatataa tatcactcct agaattgttc catacctact
    48601 tcaaataatc ctttagctgt agccatttgt gcatctttag aaactttaaa tctattatcg
    48661 aatgtcatat gtaatgctgt acctccactt acatatacat ccatttcatc tatgttcttc
    48721 catttagaag atattctttg agctgtgctt tcagaagcca taatgtaagc aactttctta
    48781 agttcatcat aatcattaga actatctatc tcattaagtt ctcttattat tcctctatct
    48841 tttagttgct tctgaaccat tgttaaagca tcttgatttc cagcttctaa tgtgtctgat
    48901 agtttatcat taaatacaaa acctttttca aagaaagaca tctcagtact tctaaaacct
    48961 attgaaacca tgccaaccgc tttatcttca tttacttttc cttctaatgt atgaaataat
    49021 gcagcatctc cttctctaaa aattgatata tcagatattt ttatttcttt atgtccacct
    49081 tttattttat cttttacttt aaatgtttta cctttatatg tgtctacaac ttcttttaat
    49141 gttgttttcc taaatgattt atatggaacg cccatcatca attttacttc atcagctaca
    49201 gctatttcat taagagcagc agcaactaat attctcattg taaaagatac tttagaatca
    49261 tcagaatttc ttataggtgt tatactttct ttttctgcta atgaaccaac aaagtaactt
    49321 acactttcaa aatctatgta tattggattt tcatatttct caaaatctat gtttcttcca
    49381 tcaccaaata ctgatttgaa taaacattct ttaaccattc cattgtactt actatatcct
    49441 tttacgtatc ctcttcctat atctaagcct ataacttggt aattttcttc cattttcatt
    49501 cctcctaagt aaatatttgc taaatatatt ataccatata aaaacttgat aattacatta
    49561 aatttgcaca aaaattcaac tataaaatga cattttttag ttattagtta aaattagcac
    49621 taaattagaa ctatatataa tttaaattta aaccaataat ttattattaa aaatttttag
    49681 ttaatattta aattatatat caactatttc caaaccaata aatcaatttc tttaactata
    49741 ctatttatgt ttttttagat gtcaatttta attttaagta aaatattgaa acttattttc
    49801 ttacagacga cattttcatt ctaatttaat aaatcttcct atatttcaag ttattttttg
    49861 tatttaatat ttttatatat attagttgtt tttatgtaat caatacatac acttttattt
    49921 tatattttcc ttgttaagaa tgtaatttaa gagtaaaaat ctaagaaata tctttagata
    49981 aatatttgtt ttatgaggaa aatacagagc tatttcgtct gtaaatccgt ctgcaatttt
    50041 tttgaaatgt ggaaatgaaa ggactacaca caaaatccta ctgacaaaca agccactttc
    50101 cataaaatac cccctacttc atttttattt attttaatat gtaaaacact ctatttactt
    50161 tatttaatta ataaaagtat tacttttatc ttattttaaa aatctatgtt tttgtcagca
    50221 aaaaatggca taaaattaag tattttatgc catttttcta aaacctagta ttttaaacac
    50281 ttacaacacc tacaccttct attttgtcag taaaatgtca gtcattataa ttcttagact
    50341 acaaacctgt tgtaatcact gcatttcaat ttttagttat tgatatctat ataaaatatt
    50401 atttgctata gaataaattt ttttgttatg gattataaag tcttatatac atcattttag
    50461 cattaatctg acatcgtcga atatcaactc acaacctcat tgccatattt ttcttgacaa
    50521 atttgtcatt attgtatata atttaattaa gataagaatt aatcttatct atacaattca
    50581 atattagggg gtgacgttat gagaataaca aaaggcaaaa taaaagagct aatcgagttg
    50641 tgccaccaac ttgaaaagct ctttgtacaa gtatttaaat cacttgaaca tattttgatt
    50701 tctttatgtt cttgtatcgg ttggttatta atacttatat acataattaa acattaataa
    50761 ccaatgcaat atacctataa aaatatatct ctataggtat attgtaacac acctaatatt
    50821 gaaagtaaac gaggtgacga catgagtcaa catattaaaa acactttaaa aataataaag
    50881 atactaggtt tattattctt cttatatttt gcacttagag caatatatat tgtttatctt
    50941 taatatcttt attgagttgc ttaatgtata agtaactctt ttttgttata atattaatga
    51001 ggtgatagca tgaaattaga aaaattaatt gatataagaa aagaaaaaaa atattctcaa
    51061 gaggatattg ctagaatgtt agacatatct ttaagaaatt atcacagaaa agaaaaagga
    51121 gagaatcaat ttacagtaag tgaactagaa aaaatatgta gctatttaga tatagaatca
    51181 aaagaactac ttgacatata gtaatataat ctactcaagg tagtacttaa cattaaataa
    51241 aataatttaa taatataaaa tagactagct ataatctagt ctattttatt ataataacat
    51301 attgtacaag ccatttaaat ccattctaag cacatttcaa tgcactcacc ttatgtttat
    51361 acctttaatc tttaaaatta aatataaaaa taagctagag tatatatgtc tagcttacag
    51421 tagttttttt aatgtgttta tttgttcttg aactatcgtt ttactcttag tatctaactc
    51481 tctataattg tctaatagat tgacttcttc ttcttttagt tgtatattct cttttaaatc
    51541 tgttttacac aatatataat ctatacttac attgtatata ttagacaact caactaattt
    51601 atctatatct atttttctat taccattttc ccaccttaag acactattat aagctacatt
    51661 tagtttatcg gctatttctt gtatattata gcctctttct tttctaactt cttttagtct
    51721 attcattttc tcaccttctt ttttacattt ataatatcat ataagataac tttaaacaac
    51781 accaaaaagg ttagtactat aaaacattca aacccttttc ggtattattt tttatttttt
    51841 atattgacat acaccctttt tggttgtata attgaatcat agcaaaggag aacaagaaaa
    51901 cacaaagcca cctctcaaat gaagtaacag gcaaagaacc ttcttaaaac tctaaagcta
    51961 atatcttaaa ggattctatt aaaaaatatt aaactactat taaaaaatta ctacctttaa
    52021 gttgaccttt taaatggtgt gaatggtgaa aggcacacaa cacaaatatt acacatagtt
    52081 ttttcttcat tttttaacta caaaaatgaa ttagtcatac cagttggtga ggtgttccca
    52141 acattaagta attaaataaa taaaattaat aaaggtttcc aattaaagcc tacaaaaaat
    52201 tgaggtatca acttagttgc ttctataatg gcactcaata caatttaata tgacatagca
    52261 gttgtgaggt actgcgttat aaaaagtact aaagattgag cattaaaatt atagtttgta
    52321 ctgcttgaca cctacatggt tataaactat ctaatattta ctaaaattat ttattattta
    52381 ttagattatt ttagtaagtg ttagaataca acacttaaat tatgatataa taataaaata
    52441 ggagtgtgaa cggcatggat gaaaaaatat tagaattatt acaaaaaatg gatactagta
    52501 ttaatgatat acaaggagaa ataaaatgga ttaatactag actagatagt atggatggtc
    52561 gttttgatgg gattgaaaac caacttagtg atttaaaaga aggacaagaa gaaattaaaa
    52621 agaaactaga cttaacttat aatcaagttg ctagaaatat ggaaggtata acagaagttg
    52681 gcgaaaaaat agacacttta aaaaatgaca tgaactttgt agaaatggct acatctaaaa
    52741 attggaatga aatagcaaag ttaaaatcaa ttaaatagga gtagataaaa tggatgagaa
    52801 aacattagaa ttgctacgag aaatacagga aagtattaaa attttaaatg acaaacttga
    52861 cgaatttgat tatacacaag ataaaataaa atctaatgtt gagggacttt tagaatgttt
    52921 tagtcgtatt gattttagaa ttgaagacct agaaaatggt caaacctcat tgtatactaa
    52981 gcttgatata gtgcaaaatg aaacagcaaa atcaattaaa tagcagtaca taaaaagaca
    53041 cttgaattat tgagtgtctt ttctacaagc tcttagtatg gtattattaa acaataatat
    53101 cattggaggt ataacgaatg tatgagcaga gaaaagcaaa agtaatattc aataaaggag
    53161 ctggtaattc tagaggagaa tcatatacga atagggttac aattccaact acatggataa
    53221 aacatatgga cataactaaa ctagacaggg aagttttgtt gacttttgat ggtaataaaa
    53281 tagtaataga aaaaatagat gagtagataa aaaatctact caaaaaaata cttgacaact
    53341 cgtgacgagt cgattataat taaatcataa aataaaattt tttacaaaat gactagtaac
    53401 gagtcagtaa aaagggagga tataaaatgc taaatatata cataactaac ctaggaaaat
    53461 ataacgaagg tgaactaata ggggaatggg ctgaatttcc agtaaacgag gaagaattag
    53521 aagaaatatt agatagaata gggataaatg aagaatatga ggagtatttc ataacagatt
    53581 ttgaaacaga tatagaaggg ttagaaataa gtgaacatag caatatagag caactaaatg
    53641 aattagcaaa agagcttgaa gagttagaag aatatgagat tgaacaatta aaggctttac
    53701 ttggatgtgg atacattgat ttttatgaca tgcttgaagg ggatatttgc agattatcag
    53761 gtaattatac ttttatacaa cttgatgaca ggtcaccatt ggatgatgaa aatttaggac
    53821 gtagttacat agaagaaata tgttgtggtg atttatcttg tatagaaaat attgcttact
    53881 actttgacat agaagcattt tcaagagatt tacgttttga tagagatatg attattgaaa
    53941 atttatacga agaagatata gaatattatg aaaatatgac agatattgaa tttgcagaga
    54001 attatattga acgattagga gatattgaag agttaggtca agaaacactt gaaagatact
    54061 ttaattatga gctatatgga actgacttac gttatgagaa tatttgtata gcatcaaatt
    54121 atttagctat agtttcttaa ataaaaagtt ttagggcgtt ctttaaaaac gccacttcca
    54181 ataaaaaaat tgaaagggga ataaatcatg aaaaaattaa taattaagat aaaatcattg
    54241 tttaaaaagg atttagatag tagctattgg agtactacag aaagtattat tttaaaatgt
    54301 ggaaacagca atcaattaga attattggaa caagctaata aattataagg aggtaataac
    54361 atggtcaatt attctgaata tatgacacag atttaataaa tatatgtgac cttttagaag
    54421 gtgaaataat aggagaagca ggaacttata attctttaag tactagacta ggaaatttaa
    54481 tcggattaga ttgggcttta aaaggagaag aattgagaca gcaattaata caaaatatta
    54541 ataatatgat gtatttagat aatgaaaata aaattcaata taaagaattt taagtaaaaa
    54601 ataattaatt tataggagga aaataaaatg aataaaataa tcgtatttta tgatatagaa
    54661 gggcatccag gttttcaagt tcttgtaaga aatgtaaaaa aatatactag acaaaatata
    54721 atatttgaat tggtagagga ttatattaaa aataatatag gtgaaattga tttaaaagat
    54781 gaaaaaatat atagtagtgt aagttggaag gtttggacta tatcagacgt agcgatatat
    54841 aataccttat ttgatttaag attagattac aataaattaa ttgaaagcga agaagaggac
    54901 actgataata aggaatgtgt aaaagaattg ttttgtatgg gtaaaggatg taaatggatg
    54961 gaaacagttt tattattaag acaaaataaa attgactctt ctcaatataa tattttaaca
    55021 ataaataatt atacatatgt caaaacatgg gcagagcaat gcaaaaaaat attattggct
    55081 aataactatt ctaaagtatt taaatttaat gagataatga aggattgtga caataattta
    55141 attggggata tatgttttaa atataataac aaggaatata agcataagtt tacatttaat
    55201 ataaaaaaag ataagttagt aaatatagat tgtgaatata aaataccttt tttaagatat
    55261 gtttttaatg atatagaaaa atttttaaca agatattcag aaaatataag taacttaaaa
    55321 taacaggagg gaaaatatga ataaaacaat tgaaaacaat ttaaatatag agcttaacaa
    55381 tactatagaa cacttaatag gaataggttt ttgagaacaa aaatattata aaccaactgt
    55441 atggaaatat gcaaatttag taatgcaaga attatgcagt atggggctta catatccttt
    55501 tgattttgga agaggtaagg gaaagtatca aacaaatatt gatgaagaga caatttataa
    55561 aagagctaaa gaaaatacaa agatacaaga atatagtaaa aagtatttaa actatattgc
    55621 taaaattaaa aaaagtataa gtaaataaaa ttcaactttt aatataattg gaggtaataa
    55681 aatgaaaaaa ataataaatg gatattcaat atataaagat ggaacatggt gcgaagtaat
    55741 aaaagaagga aaatttatct ttgctggttc tgtaaatgaa aaactatcat atgaagatat
    55801 atatatagct ttaactgcaa agttagaatt tagattacat ggtaagttac tactttcata
    55861 tagtctgtat ggtacatttc aaggggagaa acagtccaca ttagaacttt tagcatatga
    55921 aaataattgt aatataaatg acattgaagt taaacaagtt gttgaaaata tacaatagtc
    55981 tgcaaattca aaaaggaaac aaaatattaa atttaataga ttacataagt tactatcatt
    56041 gtcgatataa agttatatat taattgataa tgatagtaat ttgataaaac aaacatatta
    56101 ggggaggtat aaaaatgaaa aaaatagcta atttgaataa agaggaatta aaaataatat
    56161 gggagaaaaa tagtcaacta agggaggatg taaggaaagc ttgcgaagac aatgacatgt
    56221 attggataga tgaaatatta tgccatctta ataaatcatt agatgattgg tctattggat
    56281 tttacaatga taattatata aaaatagagg ataatcataa atttttatta gaacttaaat
    56341 ctgtatgtga aaaattttct tttttatcag aagaagaaca gagacctctc gagtatgcga
    56401 tttcattaat tgataaatta cattgtatgg attttgaaaa taaaagattt aatatgttgg
    56461 aaaataaaat taataatatg gtcaaaaaac ttgaagaaaa agtaattgaa gaatttaata
    56521 agatgacaga gccattggac aaagaatatt tattagaaaa ttttattgaa ttttatgttg
    56581 aagcctatct caatgataat gaattttata tagataatga gtatgtgtta tacgaaaaaa
    56641 ttattaaaag ttatgcttaa aagaatgtaa ttggagggtt ttaaaatgtt agcaaatcag
    56701 ataaaaggta ttaaaacatc acttgaaaca agcagcttaa gagaactaaa aggatacata
    56761 aaagatttaa gaaaagcact atcaggatat aaatataaga ataaaataga tgaaattaca
    56821 gaatatcaaa tagataaatt atgttacaaa attgataata cagatatatt tgacttgaaa
    56881 tataaagaaa tagaaaagta tatagatagt ttaattttga tacttgattt tatctttatg
    56941 gaaatgtaat caaaagaatg attttaatat aactggaggt ttaagcatga atgagtatat
    57001 tttgataagt tatacaaaag gcgaaggaac ttgtgaccac tgtggaagaa ctataaaaaa
    57061 tatagctaca ataaaaaata atgttacagg agaagttttt catgttggat taacatgtgt
    57121 agaaaaaata atgaaattga atgttacatt ttacaaagca ttgtcgagag agataaaaaa
    57181 acattacaaa tgcatggagt actacagtaa gggtttagat atagagacaa atcttaataa
    57241 aatagtgaag aataatacta aatacaaaga aggttcttat gcttataaat ctaatgaaca
    57301 aatgttagaa gatgcaattg cagaagtggc ttggtctttg gctcgtatga tagatagttg
    57361 tatgagaatg aataaactta gtaagtctgg attgatagat atagatatat tgaacagttt
    57421 gtttatcaag tataaggaat atatgagtaa atttgatgaa aattacaata aaaacaaata
    57481 taaatataaa agttgttata ctatgaaacc tttaaaagta atattagatg aaaatgaaga
    57541 tttaaaagaa ctatataaaa gtatgcaata aatgtatgta ggcgatgaat taatgacaat
    57601 gaattttata tagatgagga ttatatttta tataaaagag tgtcatatct ttaatatagg
    57661 acatgaagta ataaaagagt ttaaaattat atttttaata tgatatatga gttatcaaat
    57721 cactatcatt atagctatat tattataatt taaatgataa tgatagtgat ttgataaaaa
    57781 ggttttaaag attgtaaaaa tacattaaga tgattttcaa acagcttata gaggcttgta
    57841 cggggtcata attataaact aggaggatat aaaaatgaaa ttcaaaaata tagttatggg
    57901 aatgttatta ggtttaatca ttgtaggagt ttcaggagta acaaaagtta aggctgctga
    57961 attagataat ttttatatag agtccacaga tagagttatt gaagttttag aagatgaaag
    58021 tatagtttta tatgatacta aagagcaagt ttataatttc tatccaattt gtatgggaga
    58081 ctggaactat agctttaaaa ataaaaaaga tttagatagc gcagttgcaa cttacaaaga
    58141 gctatcaagt aatataaatc atttaagtaa tatatacgtg gttaataagt taaatgacaa
    58201 tggaaacatt aaagtatttt taaatgatgg aagttcaatt gtttatataa aacaggataa
    58261 taaatattac ttttatcctt cttgtatggg tgactggtac ttaacattgg atagtaaaat
    58321 ttatttaact aattgtatta atacttatat agaatattat tattccttgt caactggagg
    58381 tggcacaaat gaataataat gataagttat ctatattaaa tcaattggaa tacatagaaa
    58441 atgatattga tgcaagaaat gaaatgattg aaaaatttaa ggacttattg gtcaaatatc
    58501 caaagagtag agatataaga agatatataa aacaacaaac tcaattttta aatggtatta
    58561 gatatatata tgataattta gatattttga agaatatgat aaataatgac aagaagtgag
    58621 aacattacta gacataacaa tgtctactga atgtcaaaga gattcattta gtaaatacaa
    58681 agttattatg tcaattttta attaaattgt aatttaacat aaaaatgtag ttactatttt
    58741 aaaactcata ataactacat ttaataattt aaaaagggag atggaaaaag tgaataaatt
    58801 aaaagttaaa ggaaaacaaa aatttatgaa tttagaaata ccagttatag aaggtggttt
    58861 tggtgaagat aaaaaatgta tgacggataa gactatatca gaaatacata atcagcctaa
    58921 ttttaagata agagagagaa taaaggataa tataaaaaga tttaaagaag acatagatta
    58981 tatagattta aaagttatcc gtgacacgga tgacaattta gagctattac aaacacttgg
    59041 atatagtaaa atgcaaatat caaaagctga taatatattt ttattatctg aaagaggata
    59101 ttcaaaatta attaagataa tggatactga tttagcttgg gaaatacacg ataaaataat
    59161 ggatgaatat tttagtatga gaaaaaagtt aaatgaccct tttgaaaact tatctccaga
    59221 gttaaaagtt ataatcaaac tagaacaaag acaagcagaa cttgaatctg gtcaacatga
    59281 attagaggaa aaagttaatg tcctatatga tttttctact atagactaca atcaacaaga
    59341 aactattaga agtttggtaa atagaatggt aatacaagta tatcaatgtt taaatttttc
    59401 agcttatgaa gatgctaaat taagaaaaag agtatacttt tcactatgga aagattatag
    59461 aaaaaaattt ggtgttaata gctataagaa cactgctaaa aagaactatg acaatgcaat
    59521 taaattcata gaaaactggg agcctaatta tgatttaagc aatgaaatat acatgtttca
    59581 aaaagttgaa aatatataag aataatgatt ggagattatt atgatatgtt atgtcaaaga
    59641 tatacatact ataagcctat atgatgcttt tagatggcat acaatggggt tgtcattcat
    59701 tattaaagat ggtaaattaa aaggttttac aatgtaacta attaattgag aagagaatta
    59761 tgataacatt cttttctcaa ttaattatca ttcctaataa ataaagttca aaagatagtg
    59821 taaaagataa tacattttgt taatattagt aatataaaat aaatttaaaa atggagatga
    59881 atatattgat tgaaaataag tttatagaaa aattaaaata taccaaaaac ataccaaact
    59941 ctttatacaa agacttaaga cataattttt tatttcattc aaataaaata gaaggaagta
    60001 cattcacaag tgaaagttta caagatttaa ttgagcacaa cattgtaaaa ggtgaccata
    60061 ctttagatga tgttataaca acagtaaatt caagctatgt atttgaaact gtaatagata
    60121 cattgggcga atacttaact gaaaagtaca taaaggattt acatggacaa cttatgtata
    60181 attcaaatat tcataatatg gggctatctg gtatatacaa aaaaatacca aatagaataa
    60241 taggaactaa tagtgtatta gcccaaccat ttgaagtaga accaaagatg ttagaactta
    60301 ttgagtggta taataattta aaagatatta cattaaaaga cttagcagaa tttcattata
    60361 gatttgaaat cattcatcct tttcaagatg gcaatggaag aataggaaga tttatattac
    60421 ttaaacaaat acttgagaat aatttgaaat tgattataat atcgagtgat actgtagatg
    60481 attatagaca ggctttaaaa ggttgtcata atgaatatta taaaccttta gagcaatatt
    60541 ttgaaagttt agatgactac aaagaaaaaa ataaagattt atggagtttt taacctaata
    60601 attaaacaaa tgaatggaag tgaaaactat gctttacaga acggaagatt taaatacttt
    60661 tgcaggtatt ggaagttcta aaggtgttta ttgtcaactg ccactaccct aaagggtagt
    60721 agcttgtaaa agctagttga atagcctaag tttacactac gttatgtaag aatatatagc
    60781 tactttagaa tactttaaac ttaaaggaat attccacata ttaaaatact ctttttacaa
    60841 atttataatt aaatcataat ctaacttttt atttgaaaaa ctttcaatta accttgcttt
    60901 atcattagca ttctttaaaa tgtagttatt taaccaataa actatcgcat cacccctata
    60961 atggagtcca atttggactc cattttcata acaccaaaaa ggatgctcat cttctgtatt
    61021 gtcaatccaa atatgaaatt cgtttctaat ttcatatttt tttaaactaa tttcattagg
    61081 aacatatata taatcaggac tatagttgcc accaaaattt acttttataa ccataattat
    61141 agtctccttt ttaaataatt ataacatatt ttataaaaaa ctggtaatta cacttgtagt
    61201 ttaattccaa aatatagcat tctacaagtg tatctaaatt tattaaagca aaaatataaa
    61261 aaaataaagg atactatata tttaaatgca ataatttttg tatttaaata taaaaactca
    61321 tatatttatc tataatatta tatctattaa attataaata actaaagcca atatacataa
    61381 gaataaccac ccaataaagc tttcattctt actttcaaac atatttaaaa attttaatgc
    61441 atctttaaat atcaaaatag atagttttat aattacaaaa actgctaata gaataaacaa
    61501 tgttttaagc atatatttct ccttaataaa taatttaaaa tcttatttaa tataaatttt
    61561 gtttaaatta atctgttatt tataaataaa ttatatcaaa gtttgttgca ctttagaaat
    61621 atatgtaaat aaaaactatt agtcaactgg ttaatatggt atgacaacaa taatctcatg
    61681 tagtatactt aatttagagg tgagtatatg acttggaatg atttaaaaaa caatgatata
    61741 acatatatag ttgaatatat taataataag ttaaataata gtaagagttt gactaaagtt
    61801 gctatagggc ttggtgtgtc tgaaagtagc ataagaaaat accttactaa aagaggttat
    61861 aaacgtataa atgatgagta tgtgtttatt ggtgacaata gtatgacaaa agtagtaaac
    61921 aatagacaac agagtaataa tgataataca tttaatatga caatagaaga tgacaacaat
    61981 cacaacatag taattgacaa ccaatttaaa aataatatag tctctttagc aaaagactat
    62041 gataaaatac aagatgtatt aaattggttt gagaataaag aagatacaaa tgtaatagaa
    62101 gttgtacagg atggtattaa gattgattta cattcaaaag atgctataag gactacagtt
    62161 aggttgaata aagatgcatg gaatttattt gatgagtttt gtggaaaatt cagagagttt
    62221 aataagtctg atttaatgag tatggcttta ttagaataca taaagaagta tgataaataa
    62281 aaatgacaat aaaatcgtag ttttaattta aataacctca ttattttgag gttatttttt
    62341 ttattttcta tttaaaacgg agaaggtaaa tgttataata tatatataat taaaaaaagg
    62401 atgtttgaat ttatgaatta taatttaaaa aatgaaaatg tattatcaga gctattacaa
    62461 aatgaggatg aaaaaacaag gattggtata ctcaaagttt ataaagtgtt aatattttgg
    62521 tttgctaaag aaggaaagct tgttgaggaa gaaaatgact atattgttga gatagtaggt
    62581 aatgataaag aagaaattgt gagagatatg agccagaata aaacatacaa tgccataatg
    62641 gctataattt ttaaaattaa taagatattt aaaactttaa attacgatat tcacttttct
    62701 aaaccaaaaa atttagtcgc tgaatttgat ttatcaaaat atctaacaca agatgaagta
    62761 cttcaggtat gtagtaagct aactaatgca caagataagt ttataattta tgcagctttt
    62821 tgtggtctta ttggtaaaga tgctgaagac ctaaggggta taaaaataaa agacatagat
    62881 ttagaaaaaa gattaataaa gttaaaggat acagaattta agctggacaa gttcttattt
    62941 gattttacaa aagatacatt agaacaaaaa gagtataaac aatatttgga gcaagacagc
    63001 aatgctgctg aattttatct atttaattct aattctgaat atttaattaa aactaaacca
    63061 gatgctagat atggaaatgg attaaaagag atgggatact caacaattcg caaaagatta
    63121 cttattatta atgattattt agataataaa gtacagttga atttcaccaa tttaaaaatt
    63181 tctggtatta tgcatcaaat gcatctaaat gaaaaaaaat atactcaatc tggatattgg
    63241 actaacaaaa gcttgaaaga gtttaaggag gataacaatt taaacttcaa aatacaagaa
    63301 gttctatcta tttataagca aaaatatatt aaggagtaac cttatgagta aagatgttaa
    63361 agaaaacata agtaatgaac aaaaagattt aaataaaata aatttaatct atcatattat
    63421 atatgacaat gatagattta aaatgataac aagaaaatat tttgaaattt ttagattaaa
    63481 gggtatgtct gctgaagaaa taagtttaaa atttgaagaa tttctatatt ctcttatttc
    63541 agataagttt aaaaagataa atacagtaaa tgatgttaaa aaattaagaa atcaagagaa
    63601 ctcatcatca ttaaaactta agaagagatg gtctgatatg actttagatt ctctaagtga
    63661 agatactaaa tcttcaagaa aaaaaagcag taaataccta aaaaaagaat tagaaattgt
    63721 tgaaagtgaa tatttaaaaa atggaagaat cattagtgct ggagtaaaaa atccaaaaga
    63781 attaaaggag caaagaaaag attttttaga tgagtggaag tcaagctcta gttataacat
    63841 atgtgattac ccatatttac aagagttaag tactagcaaa ataaattccg catttataca
    63901 tgatatacta atgtgtataa cagaagtact aaaagatgat tatgattttg atattaataa
    63961 aattgcaatc aaaactccac cacatatttc acctggaatt tttttacctt tcacaaaagg
    64021 taaaagatac tcgcacttga atgttaaaaa aaatgaaaat gaatacatgt cagacgacta
    64081 tagtgctaag aatctttcag gtaaacaaat gaattttttc tataagtttt caattgggca
    64141 agatgaaaat attgaaaatc ttaaactaga gctaataaat cctgatacag aaaaaagggc
    64201 tttgccaaaa atatatttag ataaacaaga ccttgaaatt attagatttg tttatactta
    64261 tagccacatg aactcttttt cattttattt aggcgattta gtaaagtact taggactttc
    64321 agatggaaaa aagaactata ttaatatcaa aaatagactc ttaaaattac cttattatac
    64381 tttttattcg aatcaaacta atgataaagg cgaattaaag tatgagatta gttttaattt
    64441 gttttctagt acaacaatag taaatgatga aaacaataat aatagagagt tggttaaaat
    64501 cacaaaatct tttattgaag aagtcgaaag agttaataca gatataatgt atagaaatga
    64561 acttgaaaaa ttacaattaa cacagtcaat taatctagct tatttcttag agggtagaag
    64621 gtcttttctt atatcttgtg gtgaggatat aaaaaataaa agttttagat atgacataga
    64681 agatttaaaa tttgatgttc atcttaataa aagtaaaaca gtaaagcaaa atatggagta
    64741 tttagaacta ggttttaatg agataaaaga aaatcaattt ataattaaag actataaaag
    64801 aggaaattct tattttgatg tttatttcta tgaagatttt gaaaaaagaa aacgtcttat
    64861 aaataatact atactttctt tacctgacta catgatagaa aataaatctt aaaaatggcc
    64921 atatattctc cgtacttaac aaaaaatgtc gaatttattt taaataaact taataaaaaa
    64981 agtaaaatga ccgtatattc tccgtactta acaaaaaata gatttttcaa aaaaactaaa
    65041 tgaccgtata tcttccgtac ttaacaaaaa atagaccttt ttttaattat ttccttgtcg
    65101 aaaaattttt tttgtaacat attttttact tttcttagta atttcaaatc tcacgtcttc
    65161 tgaaatcact atgtctgagc taaatgaccg tatcagctcc gtacttaaca gaagacgttg
    65221 aaaccactct atttgagcta aatgaccgta tcagctccgt acttaacaaa tatagacata
    65281 aatttatttt ttgggtaaga taaatttgag taaaaggaat catcaccaaa atggctatat
    65341 cagctccgta cttctgaaat tattgatttt tcaaaggaga aaattatgag tcttaaatat
    65401 aaagataaag aatttgtact tgtagaaaaa aagaatataa atgaattaga taactctaat
    65461 ataaaatata ttgacctaaa ggacaagcag tattatgtgg ttacacaagg caaaaaacct
    65521 aaaagattta acctagaaga tattaaaaat ataaaaaaag atttagataa tggcataagt
    65581 ttaagaaagt gtgcaacaaa atggaactgt agcactagga ctatacagga tataaaaaat
    65641 aatatttatt aatatacaga ggtatttatt tactttatac ctcattaaga ttataataat
    65701 catatataga gaaaggagga ttataaaatg caagaattaa aaccagttgc tagaatatca
    65761 aagtcaaaac taaaagatat attagatgtt tttaaaactt ctataagaaa agtagaaaaa
    65821 atagattatt ctgcttgtaa ttcttgtgca ataaaaaata atccttcttt tgatagtcat
    65881 aaattaaatg aattttgttc aaattgtcct aaattaaaaa ctatatcaga gttttcttat
    65941 gttacagaaa aggaaacaga actaggtaca atagaaattg taactaatga aagtaaatgt
    66001 atggctttaa gtaaaagtgc tataaaacag tatttagcat atcattttat agtatctaat
    66061 aaaaattatg ttagaaaagc agtatccttc caaaatatag ccgatatatg caatgtttcc
    66121 attgttacag ccagacataa ccataatgta ttactacgag ttggattagt ttattctaca
    66181 gaaataaaaa gaggtaaatt tgatatagtc atagatgaag agtacaaaaa ccatcttaaa
    66241 aaagaagatg gtggaaaagg ttacttaact atgtcattag atactttaaa tcacttatta
    66301 agttttgaaa atgtaaatga gttaaaactt gaaattaaaa aattaatttg ggctgatgct
    66361 aaaggaagta agttaggtaa aagaatacga tttaaaaaag acaatcttat ttctatactt
    66421 ccagaataca taaagaaatc aaacaagcgt acagaagcct ttttaagaag ttctaaaact
    66481 ttatttgatg taagtaatga cacaatagat acaaagcgtt acgagacgaa agaaactatc
    66541 tcagagaaat atacagaacc aattagaata caaatatcga aattctttga taatactggt
    66601 tgctctttga gttctaatta tagtaaagtg ttatctcaga taaatttaga tagatataat
    66661 ttatttgaag aagatttaag aagtaaatta gacatggaaa aagatattat tataaatgac
    66721 ttagttggat tgtcggtgca gtatggagtt actagagttt tagcagcatt agattatatg
    66781 tttaataaat atacagttga tgaagaagat ataaattata atgaaatacg taatcctggt
    66841 gcatttataa gaacattgat tgttcagagc ataaataaaa atggaagttt agcaatagca
    66901 atttaatata tggagtagtt caaaaaaaat gattttggct actcctatta gtgtttgtat
    66961 tcaaattata aaatacttaa atagagctat aaagagcgtg aaatctctat tagctctatt
    67021 tttttatgcc tattttaatg aaattatata cacaatagaa agttttttat acatattact
    67081 aatttaattt tccaataata atatatattt attcaattta ttaagaaact tattaaaaaa
    67141 aaataataat acatcaacaa tatattatta ttaaaattta tattttattg tattcattgt
    67201 aattactttg atgtatagtt ttttcttatt ttctaattat tgaatttaat ttttgtatta
    67261 attgctatta ataatttctg tattaaacta atgagtaagt tataactatg aaacttatct
    67321 tacaaagtta ataaatatat attgcattaa gtaataatat aattacattc aaagcgttat
    67381 ataaatatat attatttaat acttcatatc ttatatatgt tatcattttt atttacctta
    67441 tttttacaaa ttattccata agtatattat aattatcttg agggaaataa tcatatagag
    67501 ggagaaatta gaaaatggat agatttgaag tattaaaata tctaaaattt aatgtttggc
    67561 attcagaatg gccattagag cttctcaaag gggctataac aaaggataat gctactggta
    67621 atttattatt acaattaaaa atgtgtaata tatctgataa ggagataaag tctgcatatt
    67681 ttacaataga atgttttaat gatgcaggag atttaataga taataattta aagtatgttt
    67741 atcaagatat aaacattaaa ccacatgaat gtcttggtga tgatattgct ataaaaataa
    67801 atgataataa aacaagagca ataaatatta tattagaaca agtagtattt tcagatgata
    67861 aagttcataa atatgaaaga gaagaaggtt taattatacc taaattagat aaaatagaat
    67921 tgttaaatat agaattatta gaagaactta aaaaagatta tgaagaatat gattttcaat
    67981 atgaaattaa gtacatgcct aatataatag aaaaaaaagc atggagctgt tgttgtggaa
    68041 aaataaataa attagaaaaa gataagtgtg ataattgtaa gagaagtaaa atactgcaaa
    68101 taaaaaagat aaataaaaat tatttagaat ctatttataa aaaaagccta aaaaagaaaa
    68161 aagaaataga aataaagctt gaaaaagata atagacataa attaaagaac ataaataaaa
    68221 ataatagaag aacatcaata ttattaataa gtatattatt gatttttatt atttttattg
    68281 gtaaaaatat tattaataag catgcttttt tagatgaaat aaagtataaa aatgaatata
    68341 gtaaaaaaat atctgtagaa aaagataatg tatatatgtt aaaaaataat ggaaaagtaa
    68401 cacatagaaa agtgaatggt gaaagtagtt ctatacctgg ttgggaaaat ataatatcta
    68461 tagcatcata tgataactca ataataggaa taaaaaaaga tggtacagtt gtttctaaag
    68521 gacttggaaa ttcagattca gacaatatta gtaaatggag agatataata gatatagaat
    68581 gtgatagtgg aacttttata ggattaaaaa aggatggtac tgtcgttgct actggaaata
    68641 atgattatgg tcaatgcaat gtgaataatt ggtttgatgt agtaagtata gaaataacaa
    68701 aatcaaccat tgagtatatg aaaaatacaa cagtaatagg cataaaaaaa gatggaaaag
    68761 tattacttac aggatatgat agtctgaatc atagaaaaga aacagacaaa tggagagata
    68821 tatcaaagat aaaatgtggg tcttatggca tatttggaat aaagaataat ggcacagtag
    68881 ttgtatcagg tagtgcttat gatattaaga attggaaaga tatagtggat atacatattg
    68941 gattatgtgg aatagtgggt attaaaagag atgggacaat aataagcaca gatgaaaagt
    69001 ttaatgaaat cattaaaaat tggaaggata ttatttctgc tgaaataata gataatcatg
    69061 aaggaatttc tattgtagga attaattcaa atggagatat tttaacatct agtagaggtc
    69121 agaatttgga taatataaaa agattagaag atgtagaata tataaatttt gatgactcga
    69181 ttgataattt tttagtaggt ataagaaaag ataatgtaat ttttataaga ggaataaaca
    69241 atactataaa tgaagaatac aacgaagaaa tataaaaata aatattttaa tttggaggaa
    69301 tagaaaatat gaaaaattac atagcaagat gtttatcaaa tatgggagta ttgttggcag
    69361 gtatacaagt attagcgggt ataataatca tgtgtcaaaa agtagaagtt ccatatgatt
    69421 atttgtcaga tacttatgaa caatatagtc ctattatgat tggtattggt gctggggtta
    69481 tagtaagtgg aatcgttata tgtttagttt taaagggatt agcagagtta gttgaaaatt
    69541 cagctgacca aacacaatat caaaaagaaa tattaatgtt gttgaaaaat aataatgtaa
    69601 atgaaaaaat taatgaggtt aaaattgaac aacaatttac aaatgaggaa ttaccaaaat
    69661 tataaaatgt tttaaattat atactaatac tcagtactaa ttaaagtact gagtattttt
    69721 atgtaacagt aaattatatt aatataaaaa tatattctac atacataaaa tgataaaata
    69781 accatttata atacattaaa ttacattaaa tcaaaaaagt atatgtcgaa aacatataat
    69841 attaaataaa tatatacttt aaggagtgat ttaatgatta taactatttg cgaaaatgat
    69901 gatatgcaaa gagatatcat ctatgatttt gttaagatat ttttaactaa aatcaaggta
    69961 aaacattatg acattttaat gtttaagaat ggggaagaac tgttagaaga atatccaaac
    70021 aaagtggatt taattttaat ggatataaat ttaggaggta gaaatggatt tgatatttca
    70081 aaagatatta gaaaatttga taaagatgca agaataattt ttgtaactgt atcagagaaa
    70141 tatgctatca aatgttatga gataaatgca tttagatata tgataaaacc gatatattat
    70201 aaagaatttg aaaaatatat gcttgacttt gcaattgatt ggagaaaaag agaagctatt
    70261 attactataa aaagaaaaaa acaaataata aaaatagagg aacataatat tttatttgtt
    70321 gaaatagtga atagaaaatt aagagttgtt actaaaaatg aagaacatat aataaatgat
    70381 aaaatggata tgtttgaaga aaagttaaaa gaggatatat tttttagatg ccataagagc
    70441 tatcttataa atttacttga ggtaactaat ttcaattata atttcgttta tttaacaagt
    70501 gagaaaataa aaattaaagt agctcctaaa aagaccaaaa aacttaaaga gaaattagca
    70561 aattttttta gggaaataat atggtaaatt aaagaaaaat ttctataatc gaatatatgt
    70621 tcttgataaa agtatgtgta caagatataa tattattagt aggaaaatag gaaaaatatt
    70681 aatatttttg aacattttga cattaattgt gattttagtg ttgaatttct gttaaaaaaa
    70741 tcttattatt taatcataga aatctactgt tatagagtag aagattgtta attataaatg
    70801 attttaaatt atctgagata aaattttttg tttctgaaaa gaacgaatgt tcgaatgagg
    70861 tgtagagtga gaggatgttt attaaaagat attagattat cttacttaat tcataatgca
    70921 tatatggggg ttctataata atgaaaaaac aagtcacaaa agaaatactt aaaatgctag
    70981 aaaaaatgga tttatcttat ttactcataa ttaaaagttt tgtatctaaa ttaaaatagc
    71041 ccttattggg ctatttacta agtttatcaa ttactttctg tatgacttct ctttcatcat
    71101 cagtaagttc agcaaatgtt aagaatactt tttttaaaaa ttcatcatta cttgagaatg
    71161 ttttacccat cattgctgct aattcaatat catctatatt tttaaacatt tctccatttc
    71221 catttcgtaa ccagtcctca tttacattaa aaacttcaca tatctgaaat ataaatctat
    71281 ctgttagctt tctttctcct ttttcaagtc tagaaatagt tgcatcactt actaataatt
    71341 tttctgcaaa ttctttttgt gagagaccta atttaattct taattccttt aaattctcat
    71401 tcatatttac acctcctatt atatagtata ttaataaaaa ttgacaatgt caataaaata
    71461 ggaatgataa attgcaaaaa gcaaaaaaaa taattgacaa atacagaatg tggtactaca
    71521 atgtaaatat acaaaacgca attaataatt tgacaaacgc aaataaataa ggaggtagat
    71581 tatttgtata ataataatga taaaaaatta ataaatttat ttgaatcatt taaaaaaata
    71641 gactatacag aacaaagttt agtgtatttt ttatctttaa gctttatagt aaacagaaaa
    71701 tgtcataaag atgcaaattt gtatagtagg agaggtgaat gtaattatga ataatttaaa
    71761 tatcaaagga aaacaaaaat ttatggattt agaaatacct attatagaag gaggttttgg
    71821 agagggtaaa aaatgtataa cagataaaac tatatcagaa atacacaata tggagataaa
    71881 acatgttaga gaattaataa ataggaacat aagaagattt ataaatgcta ttgattttat
    71941 agatttaaaa gtggtcgttg ataacgacta caatttagaa gtattggagt tgcttagtta
    72001 tagaaaaatg caaatatcaa aagcaaataa tatttatctt ttatctgaaa gaggatattc
    72061 aaaattaatt aagataatgg atactgattt agcttgggag atacacgata aaataatgga
    72121 tgaatacttc aatatgagag aacaactcat agatagttat atgatacaag attctattga
    72181 aagagctaaa agatggatag aagaagaaaa agaaagatta ttacttaaag aaacaattca
    72241 agttcaacaa cctaaagtag aatatcatga taaagtatta aatcctgaca aattagttac
    72301 gacaacagat attgcgaaag atttaggaat gacagcacaa gcattaaata aattactaca
    72361 tttaaacaga attatatatc cagaaagaat aaatggtcga ataaaatgtt ggaaaccata
    72421 taaaaattat ttatggttga tacctgaata tgcagatttt aaaataacag aacatgatac
    72481 gcagcttaaa tggactgaga taggtagaaa atggttaata gaatttgtag agaacattaa
    72541 aaaaataagt taaatcaaga agttaaaatg taccttgaaa agtagatatt taaaaatata
    72601 aaagataggt gattaaatga taaaacaaat actaaataaa agaggtagtc tattaaatct
    72661 agcaagtgag tatttgacag aacaagacta cctcaagttt caaggatggt atacacatag
    72721 atatagtaag ctggatgctt atgatgcttc tataaatgaa tatttaaatt ataaaaacga
    72781 caaaaaatta ataacttatg tatttaattt aaaatttcaa gaagctctca tagaaatata
    72841 atattactaa acatggtgat tgaaatgaat tataattatg taactaaaat tgacttgaaa
    72901 tatggaaata cacaatttgg gtttgagaaa tatagcgatg ctttagataa gtacagagaa
    72961 cttaaagaag aatttaagta tgttccatgt attataaaac ttcattcata tgtagcgcac
    73021 caagatttat atgtgaaaga aattaaagct gatggttttg aaaagaaata tttagatatt
    73081 aaaaatttaa taaaattgtt taaagaacat aaacaaaata tatcagatga actaagtctt
    73141 tgtgataaga aaaaggaaga agtattacat gtaatagaag aaatgaattt agacacagct
    73201 tctttaaatg ataagattga taccattaaa gaattaaaaa acactttagt taagagaagg
    73261 ttggttaaat atgaactaaa taaatacttt gccttttgta atacattata tgaaattgaa
    73321 gaagagttaa aaaaatatga atctaaatat aaacaaaaag aaaatcaagg aaaaagcaga
    73381 ttcaaaaaaa ataaaaaata ggtgattaga tggaagaata tcattttaac ttaataaaaa
    73441 agctttgtgc tgaaagaaaa atacacaaag gttggtttag aaatattgaa aaatgtggtt
    73501 gtggaggtaa atgtaataag aaaaattgta agatgttaga aaaattataa ggagatacat
    73561 atggaaaatc aaattgaatt aacagaaaaa gatatagaga acactttaag tgctttaaat
    73621 attattaaat atatttgtat aaaatctaaa cattgcaaaa attgtcctct tggatatatg
    73681 aaaaatcttg atgaacataa ttgtatgcta tatgaattaa tagacaaggg tttacttcca
    73741 tgtgattggt ctgtaaaaaa agttacaaga ttgttagata cgacagaaga ataaaacaaa
    73801 ggagctggtt aagtggagtt agatttcaga atttggaatg gatttagaat gatacatgga
    73861 gaagaattaa gattactaac agaagagatg tttataaaaa gtggatattc tgaacaatac
    73921 tataacgata tttgtatacc aagagtagaa gatttgaaaa taatgcaata catagggcta
    73981 aaaaattgtt ttgaaaaaaa gatatttcaa tatgatattg ttaaatttat ctttgatggt
    74041 gtttggaaag tatgtttagt aaatttatct ttgccaaaag gagcaacagt tacatttgaa
    74101 agcataggtg gaaaatatac ttttaattta agtgaaatat tttcaaaaga taggaaatta
    74161 gaaatcatag gtaattttta tgaaaataaa gatgtaatca aaaaatataa tcttagtatt
    74221 gaataggaga agaaaatgga tgaaatgata attagggtga aaatgggaga accattacca
    74281 acactaggaa agataatcaa atgtactaca tgtttaacta atgaagagaa atgttttaag
    74341 gttaataaga tatgtaaatt aagttggatt aacgatagga atagtgaagg gttaattgta
    74401 gaatgcaaag gtaaatatat taaatattaa taagaataat gaagttaaaa tcaagatttt
    74461 aatagaaaag gagtgattaa aaatgaagaa aaatccaata aaaattaaaa aatgtgactg
    74521 tggtggagat atatatgaac ttaatacaca attaggcact atgtatcaat gtaaaagttg
    74581 tggcgagatg tatagatagt gctgaaatat tagctaaaga agatgaggtg aagtcaatga
    74641 gtaaaaaaga taagttatct atttttataa gtttaatatt aagacataaa ccagaaacta
    74701 ttggaattaa attagatgac tatggatatg cagatgttaa tgaattgatt gaaaaaataa
    74761 ataatactgg tagaaatatt aatatagaaa tccttgagca aatagttaaa gaagataata
    74821 agcagaggta cagttttaat gatgatagaa gcaagattag agcaaatcaa ggacattcaa
    74881 ttaatgttga ggttgaattg aaagaattag aaccgccaaa atgtctttat catggaacgg
    74941 ctactagatt tttagagaat attaaaaagg aaggtattat tagacaaagt agactgtatg
    75001 tacacttatc aaatgatata gatacggctg ttaaggttgg gaaaaggcat ggtgtacctg
    75061 tagttttaaa aattaataca ggaaaaatgt atgaaaatgg ttataaattt tatttatctg
    75121 aaaataatat ttggttatgt aagtatatac catttgaata tgtagagaaa ataagtagag
    75181 tagttaaata aaattataga aaataggagg ttattgaatg gatttcaatt ttagaaagat
    75241 ttgtgaaaaa gatgaactta ctgatgattt tattataaaa atttgccagt tgtcacatga
    75301 ggagtttgga ggcactattt atgtaccatg taatattcat ccatgtgggt gggatgagtt
    75361 ggaagttccg aatccaaagg atttagattc agataaatta atggaagaat ttttattaga
    75421 atataaattt gaatgtgaaa atatttcgag caatatttat gatagtgacc atccatttat
    75481 aggcaaaaca ttgagagaga ttcttatgat agtggattgt agattcataa ttggtgttat
    75541 ataaggaggg tattaaatat ggaaaatata gaattaacac ctagagatta ttttgaggat
    75601 ataaaaaata aaaagcaaaa aaatacaaat gaaaatcttg atatagtata tgaaaactct
    75661 ttgattcttt taaacaaata tattgtaact ggtcaaaaaa agggtgctaa gaaattaatg
    75721 tttttacttg aatgtattga aaaagaaaga aatgtaatag agctgggaat agatacattt
    75781 gtgtataaag aagatataga aaaatatatt gatgatatat ctaaaaatac agtaaaaata
    75841 atagaacttg aaaattatga aagagaaata ccagatgaaa tagtagaaat aatagaaaaa
    75901 acaaaagata tatttgataa aatgtatgtt ttgtttactg attatacagg taaaattaca
    75961 aaggagataa gcaaagagag aagagataaa gacccaatat tatttggtgt tttttcagat
    76021 gagaaaagca gagctattgt agatagattt tattatcttg gagattggga ggatgagtat
    76081 tgtgatttaa cattagagaa aatgataaat gattataaga aaaaaggaag acaagacata
    76141 ttaaaacata taattacacc taaatcatta gatgagttaa aaaaagaatt agattcttta
    76201 gaaaaaaata atgatacata taagcaagtt gccaatataa agccattacc tactacaaaa
    76261 aactctagtg tagaaccacc taaattaaat atatttaaaa aaataaaaaa tagagtgttt
    76321 aaaaatgaaa agtaatgttg atttaacaga gaatagggat tttagagatg taagaggaag
    76381 aggcatcaat attttaggta tcgaagatgc gccaaataga atgttgagtt ttagtgattt
    76441 tggaattgga cgtctttatg gtaaaaattt agaatttgaa tttaataaaa atgaagtatt
    76501 tttaactgga aatgctaatg acagagaaga aaaaaagttt cttatccttt gtgaagaaaa
    76561 taaggtttgt gttagatgtg gtgatgaatt aagagagggg tgggataaag taagcataga
    76621 actatgtaat gaatgttatg aaatgttaga tgttgagtat aaaaataaaa agataattag
    76681 agaattattt tttagagata gagatgtaaa tatagagtta ctttaaaaaa tatataagaa
    76741 aaataagtag aggaggaatt tatatgaaag atgtttgatt atatagctgg gatgatgagt
    76801 gctttggaag tgatgaatac gaaagtagag aggaagctat tcaaggagct aataaaacta
    76861 gtatttttag tgatgacaac agtatgacaa gaataatgag aatataaagg agtgatgttt
    76921 attaaaagtt ttagatgtat attcagacat aagttttcaa ggataaaaga ttgtcaatta
    76981 attacaacaa ggagtcagca atatacctgt aaaatttgga tgtgtaaata ttgtggacaa
    77041 attgtagctg gttcaactcc tgtttatcat cctaatatga aagtcaatga gtattgtgta
    77101 aagtgtgagt tttcggcatg tgcaaataat tatgagggat attgtaactc taaagataaa
    77161 gaaattgaat ttaagtctat ttgcttaaaa ggtaataaag agattttgca gtgtaaaaat
    77221 tttgatttgg aataaaattt agcttaagta ggagaatttt agaatatgaa aataaatgta
    77281 catgttaaaa ctaataaaat tggttcagac tgtgagctgg agtttgaaat agatgatgat
    77341 gatttaaaag atatgtctga tgaagagaga gagggttata tagataaaat tgcatgggat
    77401 tatgtttttg aaaattttat agattggaat tggtatgagg ttgaagatta agttaaaaca
    77461 tttgttttaa tgtgatttta cctagtagat acaaggaggt ttttaatgaa agagctttta
    77521 gaagtaaaaa aaatatttga tagtttagca tctacatcta gtagaaaaga aaaagagaga
    77581 atattagaaa aatataaaaa taatagaatg tttgttgaat gtttacaatt tctactagat
    77641 tcaaatattc tcactggaat atctaagaat aaaatatgta agaatttaaa taatactggt
    77701 cataatgaat tagagaacat atatgatatg cttgactatt taattaagaa taatactggc
    77761 agaaatatag atgtaaaaac aatacaagta tttgccagta aagatgaaaa attaaaagat
    77821 tttattttta atttagctac aaaatcaatt aaattaggaa taacatataa gactgtagac
    77881 aaaataatgc caggtttaat tatctaataa attttgtatt ttttacaaaa aactattgag
    77941 aacatagagg ttatatgata taataaaaat atattgagaa cagagaagtt aaaaaggggg
    78001 gcaatgagat gactgacaaa ataataatag caagtgtaga tggagaggaa atgatattta
    78061 gaactgaaat gaaaaagtta gaaaaaggag atagtcttat agtttctgta aatggtgtaa
    78121 aaagattagc tctattcatt aggtatataa gtacttgtga agaatatata gaagatatag
    78181 catttcaaaa agtagatgaa atattatatg aaaacacaat tgccaaagaa aaagaaagag
    78241 ttaaaaaggt atttaaagat aagtgtatga aaaattataa acctattgtt aatacagaaa
    78301 tagactctta tttgagagaa tgtggtttca attgtgatgg tagacaattt ttcaaaagta
    78361 tagacaatac acaaatttta attagcaggg attgtgataa agatgttttg actgtatcga
    78421 aaggtttgac aataactaaa acagatataa caaataaaaa tttaattaca gttattaaaa
    78481 taataaataa tagtctatta atagttaggt aatagaaata aatattgaac ttttaataag
    78541 aaaaaagatt ttaaataaaa ggagtgattt aatgaagaat gttattaaaa gagatgggag
    78601 gatagttccc tttgatgaaa agaaaataat aaatgcaata gaaaaaagct ttttatcatt
    78661 aaggaacaaa ggaaaaagtg aagtatttga tagagaatta gcaacactaa tagctaaaaa
    78721 aataaaaaat aaaccatgtg aaaaaatgca tatagaagat atacaagata taatcgaatt
    78781 tagcttaatg gctagtaaaa agaaagatgt cgctaaagaa tatataacat acagagagaa
    78841 aagaaatata gcaagaggaa gaaaaactta taatgattat atgtctattg taaatactga
    78901 aagtaatgat ataactaaag aaaatgcaaa tatgaacgca gatactccag caggtatgat
    78961 gatgaagttt gcaagtgaag ctactaaaac ttttactgac catgtacttt tatctgaaga
    79021 agcaaaagaa gcaatgatgg ataattatat acatatacat gataaagact attatcctac
    79081 gaaatcattg acttgtatcc aacatccttt agataaaatt tttaataatg gttttagagc
    79141 gggacatggc tctagtagac ctactaaaag aatagagact tcaagtatat taggatgtat
    79201 tagtttagag actgtacaaa atgaaatgca tggaggacag gcgataccag cttttgattt
    79261 ttataatgct ccgagtgtaa gaaaaacatt tatagaagaa ataaaaaata tagaaataaa
    79321 ggatgatatt gatttatctc atttatacaa tatagaaata gaggattata taattaagga
    79381 cttaaaagaa ttagacagcg aaaaaagaaa tgttcaacat gctataaaca gaactgtatg
    79441 gagagttcat caatcaatgg agtcatttat acataatatg aacacaattc attcaagggg
    79501 tggaaatcag gtcgtgttta gttctataaa ttatggtaca gatacttcag cagaaggtag
    79561 atgtataata agagaaatac taaaatctac ttatgaagga gtcggaaatg gagaaacacc
    79621 aattttccca attcaaatct ggaaagtgaa agaaggtgtg aactataatc ctactgatag
    79681 aaattatgac ttatatgaat tagcatgtaa agtatcagct aaaagatttt ttcctaattt
    79741 tttaaattta gatgcaacct tcaataagca tgtaaaatgg aaaatgtgcg acccaaacag
    79801 atatatttat gaagtagcaa caatggggtg tcgtacaagg gtatttgaag atttgcatgg
    79861 agaaaaaaca agtataggaa gaggaaatct atcttttacg actcttaatt tagtaaaaat
    79921 ggcattagag gctaaagaaa aatatccaaa taatgaagct aatagagttg cagagtttat
    79981 ttttcttctt gataaatatt cagatgtagt agcaagacaa ttatatgata gatacttatt
    80041 tcaatgtact gctaaagcaa aacagtttcc actattaatg agtgggttat ggaaaaactc
    80101 agaaaattta aatccaaatg atgatgtaag cgaagtttta aagcatggaa cacttggggt
    80161 aggatttata ggtctagcag aatgtttaat agctcttata ggtgagcatc atggtgaaag
    80221 cgaaaaggca caaaaattag gtttagaaat catatcactt ctaaagtcta aagtagaaaa
    80281 atataaaaag aaatataacc tcaattattc tgtattaggc acacccgcag aaggtctttc
    80341 tggaaaattt actcaaaaag ataaaaaaat atttggagaa ataaaaaata ttacagacaa
    80401 agattattat actaatagtt ctcatgttcc agtttggtat aactgcaatg ttgaacataa
    80461 agcgaaaata gaagcacctt accatgaatt agaaggtggt ggccacatat tttatgttga
    80521 attagatggg gatgcaacac ataatcctaa agctataatg aaagttgtgg atttaatgaa
    80581 aaagtacaat atgggatatg gttctgtaaa tcatacaaga agtagatgta tgaattgtgg
    80641 ttttgaaaac gcagattcag agttaaaaga atgtcctaaa tgtggcagca atagtataaa
    80701 tattatccaa agaattacag gttatttagt tggaactacg gatagctgga ataatgcaaa
    80761 attagctgag ttaaaggata gagtcacaca tggataaaga ctatatttat attttagata
    80821 taaaacatga cacaattgtt gatggagaag ggtttagaac atctatttat tgttctggat
    80881 gtaatcatat gtgtagaggc tgccacaatc ctcaatcttg ggatataaaa aatggaactt
    80941 taactaaagt attagatatt tataaggaaa tcatttcaaa taaattttca gatgtaacat
    81001 tttcaggagg agacccactt ctacaactgc aaggatttgt tcatttagct aaattaatta
    81061 aaaagaatac aaacaaaaca atatggtgtt atacaggttt taagtttgag gaactcataa
    81121 cagacaatga aaagctagaa ttgttaaaat taatagatgt tcttgtggat ggaaaatttg
    81181 aagaagataa aaaatcttta gagttgattt ttaaaggttc gtcaaatcaa aggataattg
    81241 atgttcaaaa aacattgtat gaaaaacaaa tagtattata tgaataagag aggcttagcc
    81301 ctctctttgg aggtaaatgt tatgaccaaa gaagaattta ttactaaatt tcttaaagag
    81361 cagcagagaa gaataaaggt tttatattat gaagttgaaa atttcaagat ggatagaagg
    81421 tttaatgaga ggaaaaagtc taggagacat taaaatgttt cttttaatat aaggaggaag
    81481 tagctatatg tattttgaaa cggacattat aaaaaataag aatactgtaa ataaaataat
    81541 aaaatattgt ggtggaaata ctgaaaaatt gaaagattgg ctaaaagaaa tagaaaataa
    81601 aagtatcagt agtttagaag aattaaaaga atatccatta aaaagaaatt ataaatttgt
    81661 attttccaaa gaagaagctc ctaatttaga taagcttata aaaatgaaac taagagataa
    81721 ttgtttagaa aaatgtgaga tttgtagttt agaaaatctc ttaagtatgc taaatgatga
    81781 gattttagat ttaaataaag aagatatctc ttatgaagat aatattgaat ggattgaaaa
    81841 ttgtaaagaa gaactaatta aattaaaggt aggaagtatt tgcatagatt ggtagaaaaa
    81901 taaaggagtg atattgtgag attttggtgt gagaattgta ataaatactt caatgcggaa
    81961 gaaacattac aggaatataa ttatttttta aatgaagaga tacttatatg ccctagttgc
    82021 aaaaaagatt taatacctat agctagggaa acagaattat cattaggttt tgatagtgat
    82081 acaaaccaat taacttatgt tgaatatgat tctagtgatt atagtttact tagaaaggta
    82141 aatgcagatg ttgaagatgt agtaaaacct ataatacatt acataagaaa tttaaataaa
    82201 aatagtttag atttaaatgg aattacagaa tagtgcggaa agcccactcc tttaggtgtg
    82261 ggatggatag cacaaacagt gtataaaaag tattgacaca tacacgtata atgttaatac
    82321 tttgtattct gccctagata taaaagaaaa atatttaata tagaaggttt agaagataga
    82381 tttaaaacat tagttaaaaa taagtgtaag gaaatggata tcgaaattgt tgcaatagaa
    82441 tgcgataaag accatacaca tatgttttta aatagtcttc cgactctaaa tccttctgat
    82501 ataatgcaaa atataaaagg ctatacaagt aaaatattaa gagaagaatt tattgaatta
    82561 tcaaaaatgc ctagtttatg gactagaagc tattttgtat ctacagcagg aaacgtatgt
    82621 agtgaaacta ttaaaaaata tgtgaaaaac cagaaaacaa gatactagaa agtgaggtga
    82681 acactatgtc aaattatata ttaacattgc aattaaaaac agaaaagttt caagaagaca
    82741 ttatatgtaa tgcttttgat aagtatagaa aagtatataa ttcatgttta tcagagctat
    82801 ttaaaagata taaccacatg atagaatcta aagaacacca agcaaattgt aaatataagg
    82861 gtaaagatag aaataaaata tttagtgaaa ttaataagaa gtataattta acagagtatt
    82921 cacttcataa gtttgttaaa tttattggta aatattataa actacattct gctataactc
    82981 agaagatagc tacaagatgt tttaatgctt ttaataagta tatctatcat caagctaaac
    83041 gagttaatta tattagatat aatgaattaa catcaataga agggaaacaa aattcaactg
    83101 gtattagtta taaagatggt attattaaat ttaataagat gactattcca gtaataataa
    83161 agaataatga caattatgct caaagagcga tacaagataa aataaaatat tgtagaatac
    83221 ttaaaaaaga aattaagggt aaaattaaat ggtatgtaca attagtctta gaaggaattc
    83281 cacctaaaaa aacaaccaat caaggaaaaa taaaaggaca aattggttta ggtaatgtag
    83341 gtatagatat tggaactcaa actatagcta tatctagtaa atgtgatgtt aagttattgg
    83401 agttagcccc taatgttaat aatatagata ggcaaataaa gttaattcaa cgtaaaatgg
    83461 atagaagtaa acgtgcaact aatcttaata aattcaatga taatggtact ataaaacaag
    83521 gaaatagaga taagtggata tttagtaatc actatcttaa attaaaaaga ctaagaaaag
    83581 agttatatag aaaacaagct gaaataagaa aacaagacca ctatatatta attaacaaat
    83641 tactaaattt aggcaataag ttttatgttg aaacgatgag ttataaaaga cttcaaacta
    83701 gagtcaagga tactactatt aatgaaaaaa ctggtagaat taataaaaag aaacgttttg
    83761 gaaaatcatt agcaaataaa gcaccatcaa tgtttttgac tatgttagac aataagttaa
    83821 aatataataa tgaaagatta tataagatag atactgctaa atgtagagcc agtcaatata
    83881 atcacttttc agatgagtac aataagaagg aattaaaaga tagatggaat aatggtatgg
    83941 acattcaaag agattgctat tctgcatttt taataatgaa tgttaatgaa gatttaaaat
    84001 caatcaacag agaattgtgt gttaaaacat atgataactt taaaatatta catgataaag
    84061 agataaatag attaaaaaaa ttaaaattaa atggttataa attaatatct agtatgggga
    84121 tataaaaact atataggttg agaaacgagc ctaatattaa tgttaatggt gtcaacagat
    84181 actttgttaa taaaagtctt agggaatatg attagtgata atatgttgta ggttatgatt
    84241 tattataact gagagtattg tagaaattca tgtagtacct aagaacccca cgcctttagg
    84301 cgtaggagtt tcagaataac aatgaatggt aatatataag aataaaaaga aggatattat
    84361 aagagatgag tcgatgtatg attatgggat gtctttgtca tctattatga aggttatctt
    84421 aaatcatcaa gaagatatag aaaagttaaa agaagaggag gtagcagaat ttataaaaaa
    84481 taaattagaa aatgagcatg attgtgatga attaaaaata ataagtgagg tatttaatga
    84541 aatatattaa acatgtagat aatggagtaa tgagagcaat aggtattgat aattataaac
    84601 ctttattaaa catcataaaa gaaaaagtga atttagaatc taattaaaac agttttaatt
    84661 agcgaggtga tacatatggg attagattta ggtttttatt cagtaaaaac aaaagttaca
    84721 gatttagata tttatttaaa taaaacaaga ggtgagaaat ataaggaatt gaataatgat
    84781 gaagaagagt tttataagtt tgaagaatta ttagatattg atatatcttt agaagattgg
    84841 tcagttattc gtatgatata taaagccaaa tgggaaaaag gttatgaaag ttatgaagat
    84901 gaagccatac ttattacaaa ggaagatttg gaagattata taattccttt tcttaaacaa
    84961 aaagatataa attctaagat atacaataag gataaagagt attattataa aaatgataaa
    85021 aaagtaacag ttgatgatag gtatacacag gagttttggg atttagtatt aaaagaattt
    85081 caaaaaatgt taaacataat tgattttgaa aaacatagtt taattattat gtattggtat
    85141 taagataata attttaattt atttggaggt ttataataat gaaaaaaatg tacatagcaa
    85201 ttaattcaga cttaaatatg agtccaggca aagttggagc acaagttgca catgcagttt
    85261 atgattattt gtataacaaa attttagaca ctgtttcttg ctcttatgaa acagaaataa
    85321 tagcacatga attaatagat ttaaaatgtg atttaacgtc atttaagaat aatggggata
    85381 caatatgtat attaaaagct aaagaggcac aattattaaa atttaaagaa aaaggttatt
    85441 taactatagt ggatagagga ttaacagaaa ttcctaaaaa tagcataaca tgtgttaact
    85501 taggaatatt taatgaggat gaaataccat ctacaattaa aagattgaga ttatattaag
    85561 gagaaagaca ataaatgtat tctaaaggtg atgtagtaaa agtatggtgt tatcaatgtg
    85621 aaaggataga atttcaagaa tttgtaggat attttaattc ttattttgat aattataaat
    85681 taaagaaacg atggaaatgc tctaagtgtg atgtcatcaa taatttttaa gagtttaatt
    85741 aatggaggaa tgagttatga aaataaagaa aataatttta ggattagata acttagagaa
    85801 tgtagagttg ggtattggag atgtaggagg tttttattta gataatatac atgaaattat
    85861 tggaggattt gctttgagtt atataggtaa atgcaagaag gcagattatt tacatataca
    85921 aatacataaa cgtgttgatg aaattcaaag attgcatgat tataaggata ttacaaatgt
    85981 aaagatagaa tacgaagacg gaagtgtgga ggatatatat gtaccttata aacaagaagg
    86041 ggatttcttg ggtttagata atctttatca aacttctttt attagtaaac aaggttattt
    86101 acatatagtt atctctaagg ataaaacagt agaagaagtc ttcaatgaag aatttgagga
    86161 tgatgaaggg gtagaattta gttttaatat gtatggaata taaaacttaa aatggaagga
    86221 gatgagcaaa tataattaac tcttttaaga aattaataaa gtcaaaatat ataaaaaata
    86281 acgaatcaat aaaaccatta gaaagaattt ttgaatatga aataagaatc aaagaaaaaa
    86341 gaacatattt taatttagaa ttattgattt atgaaaaaag aattaagata attaaaaaaa
    86401 tatttttaaa agatatacta tgccattatc gaagagatat agaacaactc gtcatttatg
    86461 acctggataa atatcttaat atgacagata aagaaatgga ggaatatatt ataaatttaa
    86521 taaaagataa aataaaagaa gagtatgggg agaatatact tcctgaaata ctaatggaaa
    86581 aatttataaa actcgaaaga aaaggttcgg tgactgtaga cgtacgggat ttaatagagg
    86641 gataataaat aacaagttaa aatacaggtt ttaaaaggag aataacaaat ggaagttcaa
    86701 gggaaatata acaaagctaa aatatttaca gagaatgtag attcgataac aataggacaa
    86761 ataataaatt tatgtaatca aaaggaattt aaagaatcca gtataagaat tatgcctgat
    86821 tgtcatgctg gtaaaggatg tacaatagga acaacaatga ctataagtga taaagtagta
    86881 ccaaatctgg taggggtgga tataggttgt ggaatggcta ctattccatt agaaaaatat
    86941 attaataata taaattatac aaaattagat aagattataa gagattatat tcctcatgga
    87001 tttaaaatac ataataagtc aagagaaaaa ctattaaaga atttatttaa tatagacata
    87061 aataatctta gatgcgaggt gaataaaaat agagcatata tgtcgttagg aactttaggt
    87121 ggaggcaatc actttataga agttgataaa agtgaaaaag gtcaaatgta tcttactgtt
    87181 catacaggtt caagaaattt aggaaaacaa atagctgatt attaccaaga caaagctata
    87241 aaatattgta ttgaaaaata taaaaagtca tatgatgatg caaaagagtt tttaatatct
    87301 actctaaaaa aagacaataa agaacatttg ataaataaat atttgaaaga ccttagtgat
    87361 agaaaattga ataagccaca tgatgattta tgttatttag aaaatgattt aatggaagat
    87421 tatttacatg atatgagtat agctcaaaaa tacgctgctg caaatagaat ggttataatt
    87481 gcggatatat tgtttaaata taacagccta gaagtaaatt atgaccattt tataagagat
    87541 attaaatgtg atgttataga atgtattcat aactatatag atatggatag taaaatactt
    87601 agaaaaggag caatttctgc aaataaagat gaaacagtaa taattccagt aaacatgaga
    87661 gatgggatta tattaggaaa aggtaaaggt aattctgagt ggaattattc agcaccacat
    87721 ggagcaggaa gaattttatc aagaggaaaa gctaaagaaa aaatatcttt agatgaattt
    87781 gaagagtcta tgaaagaaat atttacaact tgtgtaggtc aatcaacact agatgaagca
    87841 ccacaagcat acaaacctat agaggatatc ttaaacaata taggagatac tattgagata
    87901 atggaggtgt taaagccaat ttataatttt aaaagcaatt agaatcttgt tatttaaata
    87961 aaatcaaaag gagaaaaaag ggtatgataa aattaataac acataatgat ttagatggtg
    88021 taagttgctg tattatagca aagtatattt tacgagaaca aatagatgtt aactattgta
    88081 attataaaaa tataaatgat gtagtattag atacattaaa aaatcacgat aaatatgaac
    88141 aaatattaat aacagatata tcagtaaatg aagatgttgc caagaagtta gataggatta
    88201 aaaataaagt tcaattgctt gaccatcatc caacagcact atttttaaat aattatgatt
    88261 gggctaatgt agaaatagag tgtaataaag gcaaaacatg tgggactcaa atgttattta
    88321 attatttaca aagatactat gatgatactt cagaatctac attaaaatat tttatagaac
    88381 ttgttagaag gtatgataca tgggaatgga aagataaata taatgattta gatgccaaat
    88441 atttaaatga tttaatgtat attatgggaa tagaggattt tataatggac atgttaacta
    88501 aaatagatag tgatgagatg tgtctatttg ataaattaag tttaaaatta ttagaaataa
    88561 aacaaaaaga aatagataga tatgtagaga aaaaagatga aaatataatg gttaaagaaa
    88621 ttctaggata taatgcagga attgtatttg cagaaaatca tataagcgaa ttaggaaata
    88681 aattaagtga gttacatcca gaacttgatt ttatagttat aattaatcga gaaatcattt
    88741 catatagaac tataaaagat aatataaatt taagtgaaat cgctaaagta tttggaggtg
    88801 gaggaaatcc gaaagcatca ggaagtcaga ttgatgagag ttgtatagat aattacataa
    88861 aagatatatt taatataaaa tcttaatttt aaatggaggt atatatgaaa tttgaaaaca
    88921 acatgattaa atacaattta gatttaataa ctatgatatg taagatgaaa ctaataattt
    88981 atgaggtgta ataatgatga tagataaatt caattatgaa ttatataatg agtttccaca
    89041 tttatcacca ataatagaat tgtataattt aaatatagag tacataagag aagttgtaag
    89101 tatacttatc aatacagata tgacatttca aaggtttaaa tattccaaat ctagagttga
    89161 gtgttctatg aaagcgtata ttatttcacc taatagtaag ctaagtgttg tatttgcata
    89221 cgattgtgaa ttaaatggaa ttgacttaga caacctgaag gcaattatat gagtataaac
    89281 aaataaaaat aatactttac aagaaaggta aattgaatat gtgtaagttt tgtgaaagta
    89341 taattgataa tacaaaagat atacttttaa cctcaagaag tagattatta gaagacaata
    89401 catgtgaaat tatagcagaa gataattgta ataattgtta tgatggatgt tatgaatatt
    89461 tcaaactaaa cggatataaa atcaggggaa atacatatgt taatgtcgac tactacaaaa
    89521 aaattagaaa aataataatt gctccatgtt cagaatcagt acatataaac tattgtccat
    89581 attgtggtaa acaagtttct aaagatataa aagattttaa ttgtattcct gagcatatag
    89641 tagatgttag atataaaaat ggtgatgtat atgattatga tatggaaaag tctgtacaag
    89701 aagtcatgga taatgcaaat aataattaaa taaaatgata cttttaatag gggataaata
    89761 tgaatctttg gtctaaaatt gaagaaccag tgatgagagc agtaagtgga atagtattta
    89821 atatatgggg aaatgtttgt ttttccatat attacataga agaaaataaa caaatagagt
    89881 tagaaatata tgatagacct tatagatatg aaggtaaaaa aaatagttgt tgagaagtta
    89941 tttgattaca agttaataaa tgcagattat aaagaaatac atgatattgt ttctatgata
    90001 gaaagatttt tactagaaaa ttattaaaag gagatattta aaatgaataa aggaattaaa
    90061 aactatataa cagcagtgaa ttacttactt gataatttag agtatatgat ggaggatgac
    90121 gaatttaata atgaaaagtt acagaaaaga attgatgtaa ttagaaaatt tgaaagagaa
    90181 ttataagatg ggaaaaataa aaaatggaga aatagatact gaagattata ggctttttaa
    90241 aaacattcaa aaagaaaaag atagagtata tagtaagtac attaatgaag aatacataat
    90301 ggaagaattc ataaactact taagattgga agataaagat tatactacag aaatattaga
    90361 aagatatgca cgatatattg atgaaaattt agacaatcgt tgtccatatt gtgtatataa
    90421 tatttgtagt gaacatgata attgttttga tggaatactt gaaaatttaa aagaaaaaat
    90481 taaaataaaa taaatatttt aatatgaaag gatgttgtga taataagtat aagagaaatt
    90541 atggaaatag atatagaaaa tctatcaatg aagcagcatg aagtgattaa aatatagaat
    90601 tattaaaaaa atatgataca tatatatata agaaggggca ttatagagaa atgataaaag
    90661 agagatttaa agcaaaagat agctttaata tggatgagtt cactaaaatt tggcttatgg
    90721 attttaaaga agattttgat ttaagcttaa agaaaatgat agaaaatacg ataaaaaaat
    90781 caataaaaga tacttatgaa gaaacagaaa gggcgataac aaatatagaa aatcttataa
    90841 ataaactata agtcaaaata ttactaacga cacctctaat ataagattag ttatagagga
    90901 aatctattat tagagaaggc atagattgcg tcactggaac aattcaagtt aaaaacttag
    90961 ataatcatat caaataaaat cttttacaac aaatcaaaat ttctaaaata aattcttatt
    91021 aataattcaa ttaaaactaa aggagtgaaa ttatattgaa aaagttttta ttaacagggt
    91081 tattaggaac aatgttaata gccatgtctg gatgtacagg aatacaaagt tcaatgaaag
    91141 atgctgaaag tgatgtatca gggcttaata gaactgtaaa tgtatattca gataatggcg
    91201 aggtattaaa aacatataca agtaaaagca tgagagttaa agatggagat ggtggtacta
    91261 taacactaga ttttgatggt aaaagggtga ttatatgtaa tgctcatgta gtaatagaag
    91321 aaaattcatc taataaataa aggagagtta aatgtttaaa attttaaaaa caattcttat
    91381 aataatttgg gtagtagata ttttaaactt cccacaattt caattcttag atacaacata
    91441 tccaatcaat accttagcat ggttgctaat ctggattctt ataccatcga gtagtatata
    91501 tattgacaaa aaagaataaa agaaaggagt attaatttga ttttaaatat tgctacaatt
    91561 tttaatttag gttgtatggt ggctaattac ttgcaagata atactaatgg gatactactt
    91621 aatggatttt gtcttatagc attattatta ttgaataatg acttagatta aaagtattat
    91681 tttaaggaga ttaaaagatg aaaataacaa tatcaattga agaagcaatg gatattatta
    91741 aacaacacta tgagaataaa ggaattgaaa tcaaagactt aagttttaat ttagaaaaaa
    91801 ctggaatggt tagaaatatt aaatttaagg gagaaataat acttaagtag gagatattta
    91861 tatttgttaa aaaaaagggg aagatattta taagtagtac aaatagaagt gatgctagaa
    91921 gtttccatat aagtgattat tatagaactc caattactaa aatcaaagag tttttaactg
    91981 agttcagtag atatgaaaat atactcaatt caaatataaa aatattagac ccatgtgcag
    92041 gtggagataa tacaaatcca atgagctatc caactgcaat ccaagaattt tcaaatcaag
    92101 aaatttcaat agatacagta gatataagag atgattcaag agcaaatata aagcaagatt
    92161 atttaaagtt tcagccaaaa gaaaaatacg atgtaattat tactaatcct ccctttaatt
    92221 taagcttgga tataattaat aaagctttaa atgatgtaag agaaggtggt ttcgttatta
    92281 tgctgctaag attaaattat cttggaggaa aagtaagaca aaggctgtgg ggaaataata
    92341 tgcctaaata catatttgtt cacaatagaa gaatgagttt tacagatgat ggaaagacag
    92401 atagcataga atatgctcat tttgtatggc agaaggggta taatccaaaa ttttctcagt
    92461 taaaagtatt aataagtcaa tgaaatagag gtgtaaagtt tattagagat ggaaataaat
    92521 agaagaagat gtgagtatgc tgccagaaca ggaagatatc ctaattctct tattttgtgg
    92581 gaaggttact atagccttct taatatccaa tatatagagg ataaaacaag aggatatatt
    92641 actaaattta atggcatgga tgttataaaa tgtaatgact ttttaaaaat agaattattt
    92701 gaaaagaata ttaataatta aaatttgttt tttaagttga ggtgatgagt tgagatataa
    92761 taattatcat agtcataaaa tttattcaaa tataaggtcg ttagatgtaa ttactaaacc
    92821 acaacaatat atagatagag caataaaact aggtcaaaat acatatttta cgacagaaca
    92881 tggatatcaa ggaaatgtat atgaggcaaa aactttatgt gatgaatata aattaaaaat
    92941 gattattgga gcagaatttt actatgtaaa tgatataaat gagaaagata gaggaaatta
    93001 tcatttaata gtaatcgcta aaaataatga tggttacaag caaataaata aagctttaag
    93061 tttagctaat aaaaatggat attactataa accaagaata gatgaaaaaa tattatttga
    93121 gatatttaaa ccaggggatg tagttattac tactgcatgt gtagctggaa tattaaaact
    93181 tgagaataga gaagaattaa tactaaaact aaagaattat tttaaaaata atttctttct
    93241 tgaagtacaa tctcatcctc ataaaactca agctttgcac aataaggatg ttttagaatt
    93301 aagcaacaaa tataatatag atataataca cgccaatgac agtcattata tttatccaga
    93361 agaatcaaaa tatagaacta aatttcttaa agctaaaggt ataaattatc ctgaagaaga
    93421 cggttttatt ttagattatc caaattcaga ggatatattt aaaagatatg aaaaacaaaa
    93481 tgtattaaca aagcaagaag ttgaaagagc attaaaaaat actctaatat ttgatgagtg
    93541 tgaagaaatc accttaataa atgatgatat aaaattacca tcaatatcta aaaatccaaa
    93601 taaagaactg aaagaaatat taaataaaga atggttagag aaaagaaaaa atatacctaa
    93661 aaatagatgg aatgaatact tagatgctat aaggtatgaa tttgatatta tagagaaaac
    93721 tcatatggag gattacttta ttatagatta taaaatagtt caaagagcaa aacaagaata
    93781 taatggtctt cttactaaaa cagggagagg ttcagcacct tcatttataa taactaatct
    93841 tttagggctt actgaaatag atagattaaa tgctccagta ccattattcc ctactagatt
    93901 tatgagtgtt gaaagaatac tatcagcaaa atctttgcca gatatagatt taaatgctga
    93961 agatgctgaa ccatttatac aatcaactag agatttatta ggagaagaaa attgtgcatg
    94021 gatgataagt tataagccat tacaagatgc ttcagctttt aggctatggt gtaaagcaaa
    94081 tgatatgaaa ctatctgagt atgatgaagt agctaaaaac ttagataaat atacaaatga
    94141 tgttttttgg aaagatgtaa taaaggaatc aaaggtattt gtaggagtag tagaaagtgt
    94201 ttctttctca ccatgctcta tgcttatata tgatagacca attgatgaag aagtaggatt
    94261 attaaaaact aaggatgggg tatgttgtaa tatagatgga tattattgtg ataagtataa
    94321 atatttaaaa aatgattatt taacagtgaa agtatggtca ttaataagaa aaatttgtga
    94381 attagcaaat attagtattc ctacaattga agaactaaac atcttattag atgctaaaac
    94441 ctatgacata tataaggaca aattaacttg cactataaat caggtagatt cagactatgc
    94501 tacaaacctg gcatctaaat acaaaatatc tagtgtggcg gaaacaagtg catttgtagc
    94561 tagtatcaga ccaggatttg catctttatt agacaatttt attaacagag agtcatatac
    94621 aactaacgtt aaagaactag atatattatt agaagatagt tatcattatc ttatgtatca
    94681 agaatcaata atgaaatatt taatatggtt aggaatagag gaatctgaga gttatgatat
    94741 tataaataag attaaaaaaa agagatttaa ggaaaaagag ttgaaagaat tgcatatcaa
    94801 actaaaaaat aactggatta aaaaagtcgg aactgaaaat aattttgaag atacatggca
    94861 agttgtaaac gatgctgcct catattcctt taatgcttca catagtcttt catatgcata
    94921 tgacagctta tactgtgcat accttaagtc acattatcca ttggaatatt atactgtagc
    94981 attcaattta tataatgaag atacagagag aacaagaaaa ttaacagatg aaatagagta
    95041 ttttagtatt aaattagaaa atcctaaatt tagattttca aaatctgaat acttctttaa
    95101 tagagacaca aatagtattt acaagggcat tgaatctatt aaatttttaa attctgatat
    95161 aggagagtat ctatattctc ttaaagataa taaatatgat tcatttttag agctattaat
    95221 agatttgcag gggcatataa actctaaaca attatctata ctgattaagc tagatttctt
    95281 tgaggaattt ggaaagtcca acaaactttt agagacttat gatatctata actcaatcta
    95341 tagtaaaaaa caatttaaaa gagataattt accatgcgat ataaatacca tgagaaaata
    95401 ctctaataaa gaaacagaaa aaatatttaa agaagttgat acaaaagaat tatgttctta
    95461 tcttgaaagt caaattgaaa atacagatat accaaccaat gaaaaaatac aagctcattt
    95521 tgagtttgtg ggttcatgta acataaaaga tagcaattca aatccaaggt attgtttagt
    95581 aatagatata gatactaaat attctcctaa agtcacattg tataatataa gttcaggaaa
    95641 tataaagatt ttcaaagtaa gtaaacctat ttttgaggat aataaaattg atgtttatga
    95701 tttagtttat ttaaaatcaa ttaaagaaaa agctaaaagt aaaaaagtag atggaaaatg
    95761 gattaggagc aatacagaaa cagaatggtg gatacaagaa tattggaaaa tagaaaatta
    95821 agaatatgac ctcgtatatg cgtttctaag agtttacata agagtctgct tgtatttata
    95881 cattgatttc ttaaaatggc atatacgaag ttggtgaaag gtagtgattt caatacttat
    95941 agatgaacaa agatattata gcttattgga agaaaaaaaa gacctaagta tgagaatcga
    96001 tgaattaaaa gaggaaaatg cttttttaaa acaagaaaat gaagagtatg aagaaattct
    96061 taatgagtgg gaatgtgtaa gaaaagaaat tgtagcaact tgtaaaaaaa aagaaatatt
    96121 aggtgaaaaa ccaagtgaat tagaaatggt tcttcaaaaa atagaggata tataatgagt
    96181 gtaaataaaa tttatgagaa aaaagaatac attattatca aatcaaaatc tggatatata
    96241 gtttataata caaataaaga gtttaaagaa ggccacactc acttaaaaag ttataatgct
    96301 gctaaaacag ctatagattt agttattaag agaaggcttc ctaaaagtta ttctatttat
    96361 tttcttacaa gtttgatgag aatatctaat gatgtacaat atataaaaca tataagcgat
    96421 attgtatata taagaaataa taaaggacta aaagaaaaat atataaattc taaaaatatt
    96481 aaaaaaaact attgagaaca tagaaggtat atgatatact atgaatataa caagaacata
    96541 gaaggtaaaa aggaggtagt gattaatatt tgaaatctta taaagaaaaa cagtttttag
    96601 tatttgaatt tgaagatggg aagaatgtaa agtataattt ggcaacagga gaatacgttg
    96661 gtaaatctgg aaggattgta aaagatgtgt gtactcaact tagaggatat aatttacatg
    96721 aggtaataaa ttcttttgaa gatgaaaatt ataagtgttt tttaaatttt gtagatggaa
    96781 gagtaaatag aagtaagagt agcagagctt ggggaaggag ggttgaaaga ataagaaata
    96841 taggaagttt tttaaatgaa ataaataatt attctgagta tgaacaatta ttctcagcag
    96901 gattaaaaaa aataatttat ccgatacatt gtgatattaa gagtatacct aaaggtctta
    96961 tttctatctg taggaattat agtattactt tgagtgaccg attgatacaa gggtatagta
    97021 aaaacccaaa tttgtataat aatttattaa gtttagaatt gaattcaata agaaaaacta
    97081 atttaatttc aattcttgat tctggttatg atagaatgat atttgatagg ttaatagaca
    97141 tatataaata taaacctcaa tcacttataa attatataga taatctgatg acatatgaag
    97201 cattaaatgg gcttgaaagc actctaaacg aattatatga ctatgttgtt atgatgagtg
    97261 taataagtga taaatatgaa aaatatccaa gacatttctt aacaactcat aaaatagcat
    97321 ctcgaaatta taatcgtctt aaaactcaat ttgaagaaga agtatttaat aaaagaatag
    97381 acaagtcact agaatattca tatcaagatt ataaatttat ataccctaaa aatacaaatg
    97441 aaattaaaga tgaagcagta caacaaaata attgtgtaag tagttatatt caaaatgtta
    97501 tagatggaaa atgtcatata ttatttatga gaaaaaagga taatccaagt aaaagtttag
    97561 taacaattga agttagaaat ggcaaaatag tccaagctaa aggtaaatat aatagagatg
    97621 tcaatgaaag agagcaagaa gcaattgata aatataataa tagaatagaa aggatgaaga
    97681 aaatatgtta atagaaggaa ctaaaataag attaatgaaa gaaatacaag gttttgagat
    97741 gttaaaaata ggagatatat ttgttattac atctgtggga aacaatggag ctatacattt
    97801 caaaacaaat tatgggatgg gattcatgaa ttatagtgaa ttaaaaaaat attttgaagt
    97861 tgcaatagag actaagaaaa aagaacatat ttggagcgaa tggagaactg cgactgtatt
    97921 tggaacaaat aaaacttgca catatagaac aaatggaaag aaagtagaag ttagaatggg
    97981 agattttaaa gcatcagcta cttgccatga ttcagatgag tttgaattaa ataaaggtgt
    98041 tgagttatgt ctggcaagaa ttgaagttaa aaaagcaaat aaacaggtga atttagtatt
    98101 agataaaata aataataaag aaatttagga ggttagaatg agttgtaaat ttaaagaaag
    98161 atgtgagaat aaaaatagag attgcgatta ttgttgttat aatccaaatg catatttaga
    98221 agatgctttt gaatggaatg gagaagggag aaagccaaca gacgaagagt tagatgatgc
    98281 tcttgaagaa taaataagta tttaaaatta tcattttaat atgattggag gtctttatga
    98341 ggtggagaaa tatattagta acaagtgttt tagtaatggg tagtagcata catatatttg
    98401 ctaatactaa agaaatgagt actagcagga tggataaaaa tattgtagca gatacagcta
    98461 aaaatattaa cttaatgtat aaatatgagt gggagcaaca caaaaatagt tctgaatata
    98521 aattagaaat caagagaatt aatttagaaa aggacttagg aataaaaata gaaaaattga
    98581 ttcctgtaac atgggaagta agttactata cttctttaaa ctgtgaaaat agtaaatatg
    98641 gagctattac agctacagga gaaaaattac aatatgggtt tgtggccaat aattatctta
    98701 aattcggaac taaaatatta gtcgatggaa atttaaaggt ggttaaagat agaggttcta
    98761 ataaatattt tggtaattct aatgctatag atgtatttgt accaaaatta gagggggaga
    98821 gtgattataa atattataag agagtaaaca acatgggaag acattataaa gaaggatata
    98881 ttatagttga aggttaggag ttgataaatt gaatgtaaat ggaataaaaa taccaggaat
    98941 tattgatgtg tcaaatgtgt atgtttatgg aattaaagaa agcataattg caagtggtta
    99001 tccgatgtat gaacaacagg taatagatat gaaaaaaata aacatttcag aaaaagattt
    99061 aaaacgagca aatcaattag gcaaatcaaa acaaggttca ggtcatgatt gcttttctaa
    99121 aggaattatc attcaaatgg atttacaatg gtcagaatat atgtggagac aatgggacag
    99181 atatcatcat aatgattatg tgtctagtca aagtaaaatg catagattat ctaaatttaa
    99241 tcttgatgat atgtgtaata aatatgttga taaaaataca ataaattttc taaatgaatt
    99301 aattcatgag tacaataact ttgaagaatt gaaattgaat aattctaata atattattct
    99361 tagaaatgga gaaaaagttg aagtcacaaa agaaactctt tggaaaatca taatatcaaa
    99421 ttgcccatca ggattgatgc taactgcaag agttacatta aattatctac aaataaaatc
    99481 tatgataaat caaagagaaa atcataaaat ggaggaatgg agaattctgt gtgacttttt
    99541 taaaacacta ccaaaatata aagaattaat gatgtaatag ttttgttagc aattaaattt
    99601 taaatataaa ggagaagtgg gtatggcaga aaaaagaata aattataatc aagtatttgt
    99661 atcaggagaa gttttagaca ttttaaatat agctagaatg aatcaaggaa ctggccaaga
    99721 agctataaga tttaccttaa aggttgaaac agcaccaaac gaatcagtaa atgtagatta
    99781 ctttacatca atgtttaagt cagatggttc accaaatcaa atgtttttag gaatagagac
    99841 aatagctaat gaaataaaaa ctagagcaga agatggaaaa ggtgatattg ttagatgtgt
    99901 ttgttcatta gacaataact tatattataa agatggtgaa aagaaagagc gattccaaat
    99961 atcaggaact ttttgcaata gagaaaaata tgatgacaaa ggtaatccta ttgatgacaa
   100021 aggcgaagta gtaaagtcaa taaaagcgag tcaggtctgg agagtatata cattaattga
   100081 aaatatagaa gaaaaagaag atgatttagg taagtattta gagattaagg gtttaattaa
   100141 taaatatggt aagcaaggtt gtaatatgac atttagaata cataatgaag atatgataga
   100201 aggatttaaa agtttatata aaataggaga tgttggcctt cttgaaggta cagtaaaatc
   100261 tatggttgtt agtaaatcag caggatttgg ttcaagaatt aaaaaaagtg cttttacatt
   100321 tttagaaata gaaggtggcg atgaaccttt gaaagatgga gacaaaatat ttagtgataa
   100381 aaattatcct ttcacagata agaatataga ggcaatgaga gaaaaaataa aagaaaaaga
   100441 taaaaaagaa aaacaaagag atattgataa aaatggtaag acaattgaga taagagatga
   100501 tgatgtacca ttttaaatta taaattaaat aatctattaa aaaggagaga tgtgaatgga
   100561 agttaaagaa aaaacaatga atgatggttt caagaaagtg gtaaatgagg aaataaagac
   100621 gtatatatca aatttatatt cagatagaat agacggatta aaagagagtg atagtcaaat
   100681 tgagataaca aaagcattaa tagcctttca tttagatata gaatcaattc caaaggataa
   100741 tacaaaccca tttttcaggt ctaaatatgc aaaccttgat acaattctta aagcagtaaa
   100801 tccattatta gcaaaacatg atttaatact aatgcaatca gcagaagatg caggtaatga
   100861 taaagtatat ataaaaacta aactaaagca ttcatcaggc gaatacatag agtcaaattc
   100921 tgcaccattt aaaccagcta aaactaatga tatacaagct agaggagcat tggaaactta
   100981 tttgagaaga tatgcagttc aatcagtatt agcattatca ttcgaggaag acgatgatgg
   101041 aaattcttta acaaacaaat caaagggtaa atcagaagaa gaaaattcaa ctattaagaa
   101101 aagtagagtg taaataaaat tgctacctct taaatgaggt agcaataaat acataacata
   101161 aggaggggaa atcttgaatt gtaagtgtag gttttgtaaa aagaaattaa atacaaatga
   101221 tgcttataaa gtagagcata ttacatctgg gggaaataag cagaatagat attattgcaa
   101281 tgaacaggaa tatagaaaag agcaacagga tatatatttc tggaaacaat gtcaacttgg
   101341 aatagattat attatgggat atacagttat aaataatcaa aaaaataaga tgttacaaga
   101401 gataataaaa ggtggttata cgagagaaga attatatgat tgcatcattg agaagaaaga
   101461 tgaagttata gaattactta actatagaaa agatatagaa gaagaatatc ctaaattatg
   101521 ttatgtgttt acaatattga aaggaagtat tagagatata acaattaaaa acaagcaaat
   101581 gaaatatgaa aaagaaaatg aaaggatata caaagaagta gagaaaagtg aagaatatta
   101641 tgaaataatt gctcctaaaa aagtaattta taataaaaga caaagtttat ttgacaaagt
   101701 gaaaggagtg tatcaagacg agtagttatg aaaaaataat agaggatagg ggtattatag
   101761 aaacattggt tttaggcaca atgttaaaat cattaactct ttttagtgaa tataaaatta
   101821 gcgaaagtga ctttataata gataaggtaa aattcttttt ctcgttagga agaataatgt
   101881 ctaaaacaca taacgagctt gatgaaataa gtgtagctaa atttgtatct tcaaataaac
   101941 tcaaatctga atatgaaaga tatggtggtt ggaatagttt atcatctgct atggagtatg
   102001 gaaaagaaac taatatagca gcatatattg atgatttagc taagaataat ttactaattg
   102061 ctttagataa aagaggtttt aatgtaataa aagaaatgga gcataatggg ttaaaattta
   102121 ttccatttga aatatttcaa tctatgaaat gtagagaagt ggaagaattt tatgaggggt
   102181 taatatcttc atgtagtgta aattctataa aaaataatat gaaagttgaa aatcttttac
   102241 ttactaaaga tgatagagaa aaattaaagc aaaaaactga agcaggaaca ccttataata
   102301 ttatatttga atacactgaa aaagaaatag gattgagtaa taatgaagaa tctaagtata
   102361 tatatagctt accaatatta tcaaatagga ctaatgggat tggtaagggt ggtggtataa
   102421 atataatagc agggttttca ggcataggaa aaactacttt actatttttt aattacatat
   102481 tagctatgat atatagagga gagaagatag tcatatttgc gaatgaacaa aaatctcaat
   102541 attttaagag tatgttagta tcgtttatag catataacat atttaattat catgatttag
   102601 atagaaataa aatagataat ggagatttta cagactttga agaagactta atggaaaaaa
   102661 tagaaaaatt tttaagagat agatgttttg cagagaatct aaaatttatc tatatggaag
   102721 aatttgaaat atctgaaata ctaaggaaaa gtaaagaact tgttacacat cagggattta
   102781 ctggaatagc agtggataca tttaaatcag aagattcgtc agatgcacat tatacaggaa
   102841 aattaattga aaattctaaa ttactcgata gttttgggaa caaatataat gtaataacta
   102901 tgttatctat gcaattactt acagctcaag aaaataaaag ctcatatctt tcggcaggag
   102961 atttgtcaga agcgaaagct gtcaaaaatg tatgtggttt attaaaactt atgagaaaag
   103021 tagtaaatga gttagaatta gattctacta acaagaaatt ctttttaaaa ccatataaat
   103081 taaaatataa taaattaaaa aagactactg aaagagaata tatccagttt gatgcaaaag
   103141 atttgcaaaa agaatataga ttattatttt taaataagtc aagaagaggt caagatggag
   103201 atgtaatttt actaagattt tatggtaaga ctggtagatt agaagagata ggaaggtgtg
   103261 agaaggtcta cagaggacaa ttgtcatact aggtgatgac tatggaaata aaggatttga
   103321 ctaatgaaca ggtgataaat tttatggaat atttaggttc ggacttatct cctaaaagca
   103381 atgatagaca gttaatattc aatacttgtt tatgtcataa tggtgattca tacaaattat
   103441 tttattatac agaaagcaaa acgtttcatt gctatagttc ttgtggccat ataggtagct
   103501 taatagattt attaatacac ataaataaat atgagtttaa agatgctatt aatgaaataa
   103561 aagatttctt tggtatttca aatcaaccaa tgctaagaaa aggatttaga ataaagaaaa
   103621 aagtagaaca gatacatgat attaaagata tacaaataga attacttcct acccctaaaa
   103681 agccatatgt atataaaact tttcagcaag tcccaattga agagtgggaa aatgaaaaca
   103741 tatcttttga agtccttaaa acatatcaag tatattataa tctatatgaa aatcaaatag
   103801 taattccaca tttctgttgg catgatagag ctaggcctgt tggtattaga gttagaaact
   103861 tagatgaaga taaggctaaa agttttggca aatatattcc attatggtac gacaataggt
   103921 gctataatca tagattaagt cttaatctat atggattaaa tgtaaataaa aaatctatca
   103981 aaaattccaa aaaagttatt gtatttgaag gtgaaaaatc ggtgttacaa atggctacta
   104041 tgtataaaaa taatccctct gtagctatat gtgggagtaa ttttagtaga gagcaaaaaa
   104101 agatattaat agatttaggt attgaagaat taatcatagc ttttgataga caatttaaag
   104161 ttaaagatga tgaagaatat gttatatgga gagataagat atataaatta gttcaagata
   104221 ttaaagatgt agtgaatata agtgtaatat gggataaata taatttattg ggctacaaag
   104281 atagtcctag cgataaagga aagacaatat ttgaaaaact attaaaaaac agaattaata
   104341 tagagaactt tgttaaacaa taaaaaagta aagaaattaa ttttatgaga aaatttttat
   104401 tgtttaggga tttattagca gatgctaaat aaaatatgtg ttttaatatg aattggaggt
   104461 agattacatg ataaaatttt taataaaaaa cgtacacatg ggagataaat tatattgtat
   104521 aaataacata ggaaattata aaaaaggtga aatttataca gtgagtgata ctagtttttt
   104581 tggactcttt cataaaacta aaggagaaaa ttgcttacca attgaatgtt attttataca
   104641 cttaccaaaa aaagaagagt tagaaagtaa tcctaaatca atgactaaag aagaaattga
   104701 agatgaacta ggatataaaa ttaaaatagt ttctaaataa taaagtgagg tgatattata
   104761 ttgagtatct tcaataaaaa atatggtaga aatgtaaaaa taacagaaga agaacctcct
   104821 tctcctcctc ccaaacaacc aatatataat agagataata tacaatatga taaagaaatg
   104881 gaaagaaaac tattagatat tgataggtta aaaatagaat tggaaaaaga aaaaaagata
   104941 gaagaagaaa gaaaaaaagt agaaagagta aaggaaaatg agggaaagga atgggcttgg
   105001 gttgaaggat ataaatgtac agataaaaat atgaaatgta aggaatttca atatgaatta
   105061 aacaaagcct atagtatgga tggtgatgat attaatatat ggaattgggg attccattta
   105121 tgtttagact tgggtgacgt atttcaatat tatgctccaa atttaagcaa tagatttttt
   105181 aaagtaaaag ctctagtgaa aaaagccgat aaatataaat atggtaaaga atatggtgaa
   105241 gtgactctcc tttcaggtag tgttttacgt ggtcataaaa taaataaaat agctgctaaa
   105301 gagataatat ttttagaaga attaactttt gataaattaa aactacatat acaaaatagt
   105361 tttcctgaag taaacactaa gtctaaatgg tatgccatat gtaaattagg agaacaagaa
   105421 tattatcata gaatgtttat gaatcaaatg aaaaagatta gattttcaga tacattttct
   105481 caattattat ttgatgaatg tcgtaattat tgtgaaatat tagaaatctt aaataaagca
   105541 atagcatatt caaaagaaaa tttatctaaa gatatgataa tatatttgct tatgaaagat
   105601 ataagaaagt aacatataaa aagaagggag ataatgtgga caaaataaat aagatagatt
   105661 tgattaagtt aaaagaaatg aatatatatg ataattatca attaaaaaaa atagcaagta
   105721 aaatgatatt acatctaaga tatgaaataa tggacttttg tggttgtggt tctcctgaag
   105781 atatatcttt tatgataaaa ggagtattga ctgccataca aaataaagaa aaaaattgta
   105841 atttagaata cacagaaaga tgttacatat ttgaaataga atttaataat gtttgtggaa
   105901 taattggtag taaaaatgat ttgatacaag aatttatatt aaatgcttta aattcatatg
   105961 ggttattaga acatggtagt agcatttggg ggtcatggct atctgattat ggtaaacaaa
   106021 tattatgtgc ttttgaaata gttggtgact gtattttaga tgttagctat ttagattaaa
   106081 aagttagttt taataggagg tggtaattat taaatatgta atgagtgact tacatggtat
   106141 gtatgataaa tttatttcaa tgttagagca aatcaatttc aattcaaatg accatttgta
   106201 tattttagga gatgtattag atagagggga taagtcttta gagattatag attatataag
   106261 aaagtataag aatataactc ttctaaaagg taatcatgag ttaatgtttc aagaaagtta
   106321 tacagatgta aatagtagtt ttctttggtt ttataatgga ggtaaagata cattttatga
   106381 tttaggaatg aagtcttatg aatataaaga aaatttttat aaatatatta agaaccttcc
   106441 atatttagag ataatagata attttatact agtccatgct ggactatacc ttccaaataa
   106501 ctatgagaat ctcagtatag agcaaataat tgagttacaa gaagaagata tttgtgtgtg
   106561 ggatagaaca atattaaata ctaataaaca tataaaagga tacacaatta ttattggtca
   106621 tacaccaact caaaacatta aagattatga aaaggctgaa atatataaac aggaaggaat
   106681 tataaatata gattgtggag catgttttga taatggtaaa ttggcttgtt taagattgga
   106741 tgatatgaaa gaattttata tttaagaggt gttatatgga catattaaaa atcagttaca
   106801 acaatctaaa tgctatatca aaaatatcag aagtattaag ggatattgta aatgaggaca
   106861 ctttaatagt atgtataggt agtgatagag ttttagctga ctcattagcc cctatgattg
   106921 gcagtatact agaaaaatct actattagaa ataaaatatt tggagtatta ggagattcaa
   106981 tacatgcttt aaatttagaa caaaaaatac aagcaataaa aaataattat ccaaattcaa
   107041 atataatagc cattgatgct tgtataagta aaatttcaga taaaggaaca attataatta
   107101 gcaataaacc tgttaaacca ggtttggggg tagataagaa gttactagaa gttggtgatt
   107161 attcaatagt tgggattata ggtagaaata aatatgatat atatgatact tcagaccctg
   107221 aacttatact tgatttagct gatgttatat cgaaatcttt aatatctata ttattagaaa
   107281 aagaagaaag gatgattgta tgatacagga agtcagacaa gaaatactat taaaaaatgg
   107341 tttgatttta tatacaggtg atttggtaga aataaaatac aaatcagatg aagatgtaat
   107401 agaacatact tgtaaaggta aaattaaaga agcaaaagaa ttatttatta aattagatac
   107461 aagtaagaaa tataaaactt ctgaaagaat gatttattct tgggaattaa aagaaataaa
   107521 aaaggtggat gatgaagatg aaaaagataa ttaatagtaa atatagagca ttatatttat
   107581 ttatattttt tctaattttc aatttaatat atagtttata ttttggaagg aatacggaga
   107641 ttggatttta ttctagtaca tcttgcatag aagaatatat actggatatt ataacctcta
   107701 taggactatt tttctcaatg atgttagctg ggtttgatgt tacagaaaac tttataaaca
   107761 gtttaaggga ttattgtgaa gaagatgcaa agtgaggtga ataaattgga attaaaggat
   107821 tatataagta aagtagaatt aaatgacatg ccattgacct tagacaataa atacatgtta
   107881 aatgaaataa gcatatctga agatagcaaa atctttgctg taaaagacac atcaggaata
   107941 acatcttatt atactgaaat agaatttaat aaactattta gaggaattaa tagcatccta
   108001 gagaatatta tctaatatat atttttaagg aactgagggt tgagagctat taattaatag
   108061 ctctctattt ttttgaaagg ggagaattaa tggaaaagga actatacagc tttagtaaat
   108121 taaatgcatt taacacatgt ccatttcagt actatcttac atatgtaaaa aatttaaatc
   108181 gagaacaaag ttgttacggt tattatggca atgaattaca tagtttacta gaacaattac
   108241 aacaaagaaa aataacaaat caagaagcta ttcaaaaata caatgaagtt atagaatatg
   108301 caaatctaat ggattacaat tttcctacac caaattcaag aattaattat ttagaatgta
   108361 tattacatta tatagaaaat tttgtaccaa ttgaatgtga tagatactat atagaagaat
   108421 attttgagtt tgatattaat ggaattacaa tgaggggata tatagactta tattatataa
   108481 taggtaataa aatttatgtt atagattata aatcgagtag taaattttct aaaaaagacc
   108541 tacctaaaaa atcaatgcag cttatcttat atgcaatgta tcttaaagaa aaatatccag
   108601 ataaaataat tgaatatgta gcttttgata tgtgtaaata tatgaataat gaaaaaggag
   108661 tattaattga aagaaataag attgatagta taaatgatta tgaaagagct atagtaaaaa
   108721 ttaaatatac taaagaacta gagaaacaat taattgattt tgttgttgat acagttactc
   108781 aaataaaaca gctagattcc aacgatgaga gcgtttggtg caaaagtgat gacaaaagta
   108841 atcagttttt ttgtaaaact ttatgctctc attataacaa gggttgcaaa cataaggaaa
   108901 acaagagttt tagaaaatca aaatcataat aaaatgtaga ttttaataag attggagagt
   108961 gtttaaatga atataccaaa gcaagtaaaa gtaggaggtt tattctataa aatagaagag
   109021 acagaagaac ctattttagt aaataatcaa ttatgttatg gattagctga ttatggaact
   109081 gaaacaataa aattatctaa taatctacaa tcagaaagag taaaagaagc tactttctta
   109141 catgagttat tccattgtat atttagagat agatgtatag agagtgaaga tgaggaatat
   109201 ttagtagatg tattaagcaa gggacttcat caagtgatta ttgataatcc taatatattt
   109261 gaacttaagg tgagtataga tggataaatt aaaaaatata tttgtatttt taggttattc
   109321 tggctcaggt aaagatagta tagtaacaga aatttcaaag caattcaata ttccaattct
   109381 aatatcacat acaacaagac ctccccgtaa ttacttagaa atcattaata aaacctatta
   109441 ttttgtagat aataaattct ttaagaaaga aaaaaataac tttatagaaa tgagaaagta
   109501 tatagttcat gatggcagca cttggctata tggtatacat aaatctgaat tagagaataa
   109561 aaaatatgct ttgactatag tagatgcaag tggatataaa gcactagaaa aatattttac
   109621 aggaacaaaa actaagttag taccattttt tataaacgca gatgaagata ctataagaaa
   109681 aagattaata gatagaggtg ataatcttaa agaaatcgaa agaagattag ttgatgataa
   109741 gattaaattt aaagagtttt taaatagtga aaactacatt gtaatagcaa ataacttaag
   109801 tataactaat gcagtagagc aagttaaaat acatatgaaa gaggggattc aatggtctta
   109861 gccttagatg tatccatgtc ctcaactgga tgggcagtta taaatagaaa taagaatata
   109921 ttaaaatatg gaaaaatagt aactaaaaaa gataaattca agtctgaaga tgagcgaatg
   109981 tgttatatct gtaatgcaat tcaagagtta attataactc ataatattca aatagtctta
   110041 attgaagacc aattcacttc aagaaactct aaaacaattc ttagtttaag aaaactctta
   110101 ggagcaataa tgaggactgt aaaattaaat aatatagaga ttgaatatat gtatccagtt
   110161 tctattagaa aatatctcct gaataatggt aaagctaaaa aggaagaagt agctgcatat
   110221 gtaagagaaa acattattga tattggagaa tatattgata ggacttgtaa ggctaaaaca
   110281 agtgatatat atgatgctat agcacttgga atagcttatt taaacaaact tgatactaat
   110341 agataatttt aaaaagggag attaaattaa tgagtataaa tgttaaaata aagaaattaa
   110401 atcaaaatgc aatagtgcca tcttatgcaa aagaaggtga tagtggaata gatttatata
   110461 cactaaaaga tacggtgatt ccagctaaat cagcagtagc aatatctaca ggtatatcat
   110521 tagaaattcc atatggatat gaaatgcaag tcagacctag aagtggtata agcttaaaag
   110581 gaatgttttt tacaagatat gtgactatat atgataaagt gcaacctaaa aaacaaatta
   110641 gaaaaatttt tgtagcacat ccaactgtaa gattaggtac agtggattca ggatatagag
   110701 gtgaaattaa aataattaca tataatgaag aggattttga tattttaatt cctaaacata
   110761 ctaaacttgc acaaggagta tttcaacaag ttccaagagc tatattaaaa gtggtagatg
   110821 aattgactag ctctgaaaga ggaagtaatg gatttggaag tacaggtata tagatgaata
   110881 agtatataat cctagaaaaa tataattatt actatgatga caaatgtatg acattatatc
   110941 atttagaaaa tatctataca ggattaagat tttctattga aaaaattgaa ttagagtact
   111001 ataatatatc ctagactaac tttgggagga gtattaaatg tacagatatg atgattatgt
   111061 aaatttaata aatgacttag aattaccaaa agaaattagg aataaatgtg ttagagttat
   111121 aatgacacta gagaacatgc aggatattat ggtagtacat aagtttaaga cttatgttgt
   111181 taatgaaaaa tatattgaaa aagtagcata aaataattaa gtcatctatt aatttaggtg
   111241 acttttttgc atttatgtcg aatatttcat ctacttcata ttgtattaga tgctataatt
   111301 aaaatatatg tcgaaaggta gatggtgagg atgtttaagg agatatttga aaaggtattt
   111361 atgtcagaag aagttagtaa aactgtaaaa gaagttaata atattattaa ggatactaag
   111421 atacaagtaa aaggtggatt tggagaactt agattagatt ttatacttag cagattaggc
   111481 aaagattaca taataattaa agacattatt gtaccaggct caaataagac tacacaaatt
   111541 gatagtattg tgatttctat gtatggaata tttgttatag aatgtaaaaa ttttagtgga
   111601 tatatttacg gaaatgataa agataaagta tggactcaaa ttgtaggaaa aactaaaaat
   111661 acattctata atccggtaag acaaaattat gctcatatta aagcaataga aaatataata
   111721 ggaaataaat ataatatata ttcaataatt gttttttcag acaaagctac actaaaaaat
   111781 gtaatgataa gtggaaataa tattatagtt ataaatgaaa gtgagatatt aagtacaata
   111841 agtaaatgta aagatgtgac tattgataaa gaagaaataa aaattatcag agataaaatt
   111901 tttgattgta tgaaaaccac taatcaaaat actagagagc atgttagaaa tttaaaaaat
   111961 attactgaag aggataagtg ccctagatgt caaattggac atttgattaa aagaaaaggt
   112021 cagtatggtg aattttgggg atgtagtcag tatccaaaat gtaaatacac tagaaaataa
   112081 aaaacaacct cttaaattcg attttaaggc tttgtaaaaa ttaatgctta taattaatcc
   112141 tgttcggaaa atcgattgct taaaatggaa aatatataaa aataatagcg tgatagtgta
   112201 aggcatagaa ttgtgtattc tatgtcttat ttctttacaa ctaagtaatt tcaataatta
   112261 tataaataaa agaattaaaa aagtcagttg aaagtcagct aaaatgacta ttttttgcct
   112321 cctctgtatg gtataataag tatatgaatt ttgataggag ggatagtcat gaacgctttt
   112381 ataagaaaaa gaaataaaaa ttatgtagtg tacttagaat ttagagatga tgaatcagga
   112441 aaaagaaaac aaaaaaatat gggagcattt gataaaaaga gagatgctaa taaaagattg
   112501 gctgaagtta aggacagtat atataaagat agttttcttg ttccaaatga aatcactcta
   112561 gctggattta tattagactt tcttgaaaaa tataaagata atatttcggc atctacatat
   112621 aaaagctata ttgctatttg taaaaatcat attaatcctt ctattggaaa atatcgtctt
   112681 caagagttga gaaatattca tatacagaat tatatagatg atttagctgg taacttaaat
   112741 cctcaaacta ttaaagtaca tataaatgta ttgagacttg caataaagag agcgtataga
   112801 attaagttaa taaaagaaaa tattatagat ggtatagaaa gtccaagaat taaaaaattt
   112861 aaaaatgaaa tttatgataa agagcagatg ctaaaattat tagagttagc taaaggaact
   112921 aatatggagc ttcctattag tttagctata ggtctaggat taagactttc agaagttttg
   112981 ggattaactt gggataatat tgattttgat gaaaatacaa taacagtaaa taagataact
   113041 agtagattag atggttctgt tatacttaaa gagccaaaga cagaaagctc tgttagaaaa
   113101 atatttgcac caatagagct tatgaattta ctaaaaaatt ataggctgga gcagaataag
   113161 aaattattga gaagtattgt tagaaatgaa tataacttac tattttttga tagaaaaggg
   113221 aatccaattg ctgaagatgt aatgagtaag aaatttagaa aattcttaga gaacaatgat
   113281 ttacctcata ttagatttca tgacttaaga cattcacatg ttactttact tataaattcc
   113341 aaagtaccta taaaggttat atctgaaagg gtgggacatt caaatattaa tactactctt
   113401 aatgtatatt ctcatgtact taaagaaatg gacaaagaag cttctgatag aatatctgaa
   113461 aacttattta aggctaatta ataattatta tcaataaata caaaattaat aataaaagca
   113521 aaggtataaa cataaagggg aatttttaca aagccttaga atggcatata gagcgtcaga
   113581 ttttagaaga tattaaaatt ttatatttcc aatatttatg atataataaa catagcaagg
   113641 aataaatatt tgaaaaagct gtgagtggtg tttccataga aatttcctca ctttcttatg
   113701 aaaggaggtg aaaaactatg gaaaatctaa tgatgagtat tatagctggt gttatagcta
   113761 gttatatcta cgataaatta aaaagccact caaacgcgac taagagtggc tgggaactta
   113821 atattaagtt ccaaagaaaa tccaaataaa ctaatttagt ttggaaacat cactcaaagt
   113881 taagtaaaat atgtttcctt gcttttatta taccacaaat taagaatatt aaaacaaaat
   113941 ttcatgtaaa taacatttaa tctgtaattt ttctattttc aaaaaaaact aactaaaagt
   114001 tgaaatataa caaatccaac tgttgaacct aaagcattta taggtactga tgttatatta
   114061 gtaaagttat ttaaagctga tatccctagc attactatag aaactatagc caaataagag
   114121 ataactaaaa aaattggtat tgatatactt atattaatct ctaattcagg caatttcata
   114181 atatcattcc tttcaacatt cttatattta accttattat accattaaat ataagaaatc
   114241 ataatgtaca aaataactta tttttaatta catactatga aagagagtgc ttttaatggg
   114301 gtctatgttt tatatatact attccttaaa aatctattta aagaatacta tcatagaaac
   114361 atatcttgtt agattttgag ttaaaagcta cattatttga ttcatttcct atctgaaatt
   114421 atattgtatg taaatcccct gaaaatttat ggttaaatac atattcttga ttatcaatag
   114481 taactatttc tgtaaaatct tttttagaag cattataagt attgttttca gttagataag
   114541 tattgtttgt ctttgtaaaa ttaacactcc tatctatgaa tgataattca acctaactta
   114601 atcatattgt tgtcacacaa cctaatgcaa ttaatctact ctgtattttt ttatcttgtt
   114661 ataccctcta cttcaattct attttaatag aattttatca tgtatagtaa caattggcaa
   114721 tataaatttt aattagttta taaaataaaa atttaaaata tttaatattt aaaatatcta
   114781 atatttaaaa taaaatacaa aaatttgttt ttatttattt t
//
LOCUS       DAEHWO010000004       103210 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEHWO010000004 DAEHWO010000000
VERSION     DAEHWO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 103210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 103210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103210
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.004"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(359..871)
                     /locus_tag="KNP54_000400"
     CDS             complement(359..871)
                     /locus_tag="KNP54_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0891330.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            1321..1797
                     /gene="purE"
                     /locus_tag="KNP54_000401"
     CDS             1321..1797
                     /gene="purE"
                     /locus_tag="KNP54_000401"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBF0891331.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDNNLRG"
     gene            1803..2501
                     /locus_tag="KNP54_000402"
     CDS             1803..2501
                     /locus_tag="KNP54_000402"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBF0891332.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            2513..3880
                     /gene="purF"
                     /locus_tag="KNP54_000403"
     CDS             2513..3880
                     /gene="purF"
                     /locus_tag="KNP54_000403"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBF0891333.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            3874..4950
                     /locus_tag="KNP54_000404"
     CDS             3874..4950
                     /locus_tag="KNP54_000404"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBF0891334.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMERYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAVAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            4944..5537
                     /locus_tag="KNP54_000405"
     CDS             4944..5537
                     /locus_tag="KNP54_000405"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBF0891335.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            5530..7062
                     /gene="purH"
                     /locus_tag="KNP54_000406"
     CDS             5530..7062
                     /gene="purH"
                     /locus_tag="KNP54_000406"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBF0891336.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            7073..8323
                     /gene="purD"
                     /locus_tag="KNP54_000407"
     CDS             7073..8323
                     /gene="purD"
                     /locus_tag="KNP54_000407"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBF0891337.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            8348..12154
                     /locus_tag="KNP54_000408"
     CDS             8348..12154
                     /locus_tag="KNP54_000408"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBF0891338.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKETSIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            12360..13232
                     /gene="rfbD"
                     /locus_tag="KNP54_000409"
     CDS             12360..13232
                     /gene="rfbD"
                     /locus_tag="KNP54_000409"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBF0891339.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIKIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            13341..14210
                     /gene="rfbA"
                     /locus_tag="KNP54_000410"
     CDS             13341..14210
                     /gene="rfbA"
                     /locus_tag="KNP54_000410"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBF0891340.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            14259..14816
                     /gene="rfbC"
                     /locus_tag="KNP54_000411"
     CDS             14259..14816
                     /gene="rfbC"
                     /locus_tag="KNP54_000411"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBF0891341.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            14854..15837
                     /gene="rfbB"
                     /locus_tag="KNP54_000412"
     CDS             14854..15837
                     /gene="rfbB"
                     /locus_tag="KNP54_000412"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBF0891342.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            15867..16535
                     /locus_tag="KNP54_000413"
     CDS             15867..16535
                     /locus_tag="KNP54_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBF0891343.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVNQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            16544..16972
                     /locus_tag="KNP54_000414"
     CDS             16544..16972
                     /locus_tag="KNP54_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBF0891344.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            16996..17310
                     /locus_tag="KNP54_000415"
     CDS             16996..17310
                     /locus_tag="KNP54_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBF0891345.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVKVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            17461..17736
                     /gene="flgM"
                     /locus_tag="KNP54_000416"
     CDS             17461..17736
                     /gene="flgM"
                     /locus_tag="KNP54_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBF0891346.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            17741..18157
                     /locus_tag="KNP54_000417"
     CDS             17741..18157
                     /locus_tag="KNP54_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBF0891347.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGNDISMSEVVENSNDGYLKEIYTDLKRILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            18175..19485
                     /gene="flgK"
                     /locus_tag="KNP54_000418"
     CDS             18175..19485
                     /gene="flgK"
                     /locus_tag="KNP54_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBF0891348.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            19504..20436
                     /gene="flgL"
                     /locus_tag="KNP54_000419"
     CDS             19504..20436
                     /gene="flgL"
                     /locus_tag="KNP54_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBF0891349.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            20452..20844
                     /locus_tag="KNP54_000420"
     CDS             20452..20844
                     /locus_tag="KNP54_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBF0891350.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            20838..21050
                     /gene="csrA"
                     /locus_tag="KNP54_000421"
     CDS             20838..21050
                     /gene="csrA"
                     /locus_tag="KNP54_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBF0891351.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            21072..21467
                     /gene="fliS"
                     /locus_tag="KNP54_000422"
     CDS             21072..21467
                     /gene="fliS"
                     /locus_tag="KNP54_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBF0891352.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            21467..21823
                     /gene="fliS"
                     /locus_tag="KNP54_000423"
     CDS             21467..21823
                     /gene="fliS"
                     /locus_tag="KNP54_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBF0891353.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            21844..23367
                     /gene="fliD"
                     /locus_tag="KNP54_000424"
     CDS             21844..23367
                     /gene="fliD"
                     /locus_tag="KNP54_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBF0891354.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSINSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            23370..23705
                     /gene="fliT"
                     /locus_tag="KNP54_000425"
     CDS             23370..23705
                     /gene="fliT"
                     /locus_tag="KNP54_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBF0891355.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            23807..24679
                     /locus_tag="KNP54_000426"
     CDS             23807..24679
                     /locus_tag="KNP54_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBF0891356.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            24772..26913
                     /locus_tag="KNP54_000427"
     CDS             24772..26913
                     /locus_tag="KNP54_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBF0891357.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            26937..28814
                     /locus_tag="KNP54_000428"
     CDS             26937..28814
                     /locus_tag="KNP54_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBF0891358.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            28807..30921
                     /locus_tag="KNP54_000429"
     CDS             28807..30921
                     /locus_tag="KNP54_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBF0891359.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDRIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            30930..31925
                     /locus_tag="KNP54_000430"
     CDS             30930..31925
                     /locus_tag="KNP54_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBF0891360.1"
                     /translation="MNNIHINKFEKSCERNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLREQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            32017..33249
                     /locus_tag="KNP54_000431"
     CDS             32017..33249
                     /locus_tag="KNP54_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBF0891361.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIELYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            33269..34213
                     /locus_tag="KNP54_000432"
     CDS             33269..34213
                     /locus_tag="KNP54_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBF0891362.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ELFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            34307..34714
                     /locus_tag="KNP54_000433"
     CDS             34307..34714
                     /locus_tag="KNP54_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBF0891363.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKVIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            34801..35892
                     /locus_tag="KNP54_000434"
     CDS             34801..35892
                     /locus_tag="KNP54_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBF0891364.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      36201..36291
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            36700..37017
                     /gene="flgB"
                     /locus_tag="KNP54_000435"
     CDS             36700..37017
                     /gene="flgB"
                     /locus_tag="KNP54_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBF0891365.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            37025..37429
                     /gene="flgC"
                     /locus_tag="KNP54_000436"
     CDS             37025..37429
                     /gene="flgC"
                     /locus_tag="KNP54_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBF0891366.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            37439..37756
                     /gene="fliE"
                     /locus_tag="KNP54_000437"
     CDS             37439..37756
                     /gene="fliE"
                     /locus_tag="KNP54_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBF0891367.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            37781..39331
                     /gene="fliF"
                     /locus_tag="KNP54_000438"
     CDS             37781..39331
                     /gene="fliF"
                     /locus_tag="KNP54_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBF0891368.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            39344..40414
                     /gene="fliG"
                     /locus_tag="KNP54_000439"
     CDS             39344..40414
                     /gene="fliG"
                     /locus_tag="KNP54_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBF0891369.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            40407..41138
                     /locus_tag="KNP54_000440"
     CDS             40407..41138
                     /locus_tag="KNP54_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBF0891370.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIRKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            41142..42461
                     /gene="fliI"
                     /locus_tag="KNP54_000441"
     CDS             41142..42461
                     /gene="fliI"
                     /locus_tag="KNP54_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBF0891371.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRIFE"
     gene            42493..42939
                     /gene="fliJ"
                     /locus_tag="KNP54_000442"
     CDS             42493..42939
                     /gene="fliJ"
                     /locus_tag="KNP54_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBF0891372.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDNVQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            42967..44172
                     /locus_tag="KNP54_000443"
     CDS             42967..44172
                     /locus_tag="KNP54_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBF0891373.1"
                     /translation="MKIQADSYNIIKDIGNRKNSSKNKNIKNNKFEDNLYKTTDHKNV
                     KDRRETSKQNVSSDRPGNSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     ENYKKDKDINTILNNIKKLSISDELKQELKLNKNILNKIANQNLELNGANTNNPNDIE
                     NLDIMKLRELLENNASEDIQVISKTTENDTKSIDLYSFDSNRMDTLNSNKQKDDSSDI
                     LEKLAGLNGNKSGNFGQVINKSVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSNQNTNDKRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            44190..44798
                     /locus_tag="KNP54_000444"
     CDS             44190..44798
                     /locus_tag="KNP54_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBF0891374.1"
                     /translation="MYGIATALAGTQVNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMND
                     KLDILLALSNSTLINSALSMATSLIGKEVEVSGEEDEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVDVKYEKLLKIGEVEANSGEENDSSEQESPEEV"
     gene            44825..45808
                     /locus_tag="KNP54_000445"
     CDS             44825..45808
                     /locus_tag="KNP54_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBF0891375.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            45821..46024
                     /locus_tag="KNP54_000446"
     CDS             45821..46024
                     /locus_tag="KNP54_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBF0891376.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            46024..46842
                     /locus_tag="KNP54_000447"
     CDS             46024..46842
                     /locus_tag="KNP54_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBF0891377.1"
                     /translation="MKKTDSLTFIGLILSTVLVLFGAVKGSSSGLKSFFDFASILITV
                     FGSFGALMITFTIDDIKLIKDALQYSFKTMNISKLDLLNQFKTLSKKARREGLLSIES
                     DVMKIQDPFMKKGLELCIDGLEINEIRSILELEIDSVEETNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            46832..47527
                     /locus_tag="KNP54_000448"
     CDS             46832..47527
                     /locus_tag="KNP54_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBF0891378.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSMFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKEDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPKLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            47539..47982
                     /locus_tag="KNP54_000449"
     CDS             47539..47982
                     /locus_tag="KNP54_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBF0891379.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            47997..48371
                     /locus_tag="KNP54_000450"
     CDS             47997..48371
                     /locus_tag="KNP54_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBF0891380.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILRIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            48372..49037
                     /gene="fliP"
                     /locus_tag="KNP54_000451"
     CDS             48372..49037
                     /gene="fliP"
                     /locus_tag="KNP54_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBF0891381.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            49050..49319
                     /gene="fliQ"
                     /locus_tag="KNP54_000452"
     CDS             49050..49319
                     /gene="fliQ"
                     /locus_tag="KNP54_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBF0891382.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            49331..51145
                     /locus_tag="KNP54_000453"
     CDS             49331..51145
                     /locus_tag="KNP54_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBF0891383.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLINNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKSFIDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPIAMTLLAFTLLVPTLFSYVVNTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            51154..53229
                     /gene="flhA"
                     /locus_tag="KNP54_000454"
     CDS             51154..53229
                     /gene="flhA"
                     /locus_tag="KNP54_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBF0891384.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            53204..54220
                     /gene="flhF"
                     /locus_tag="KNP54_000455"
     CDS             53204..54220
                     /gene="flhF"
                     /locus_tag="KNP54_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBF0891385.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIRGIFS
                     KKDIELTIGWEKKDNLEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLNLDLN
                     QEIVEFIKADLQEMKFNGIDTSKNLVESLKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            54217..55095
                     /locus_tag="KNP54_000456"
     CDS             54217..55095
                     /locus_tag="KNP54_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBF0891386.1"
                     /translation="MIDQAQILRKMAMEKRGSDEIIVENENMPKIITIASGKGGVGKS
                     NLATNLSICLTKLDKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHNVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKKSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVGVCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            55109..55810
                     /locus_tag="KNP54_000457"
     CDS             55109..55810
                     /locus_tag="KNP54_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBF0891387.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDTEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            55826..56248
                     /locus_tag="KNP54_000458"
     CDS             55826..56248
                     /locus_tag="KNP54_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBF0891388.1"
                     /translation="MIQIILIVVSILIIVTIVINLQKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            56233..56418
                     /locus_tag="KNP54_000459"
     CDS             56233..56418
                     /locus_tag="KNP54_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBF0891389.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            56459..57232
                     /gene="flgG"
                     /locus_tag="KNP54_000460"
     CDS             56459..57232
                     /gene="flgG"
                     /locus_tag="KNP54_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBF0891390.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            57253..58014
                     /gene="flgG"
                     /locus_tag="KNP54_000461"
     CDS             57253..58014
                     /gene="flgG"
                     /locus_tag="KNP54_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBF0891391.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGKDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            58037..58918
                     /locus_tag="KNP54_000462"
     CDS             58037..58918
                     /locus_tag="KNP54_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBF0891392.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNECIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            58921..59295
                     /locus_tag="KNP54_000463"
     CDS             58921..59295
                     /locus_tag="KNP54_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBF0891393.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            59327..60730
                     /locus_tag="KNP54_000464"
     CDS             59327..60730
                     /locus_tag="KNP54_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBF0891394.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYNSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            60846..62783
                     /gene="htpG"
                     /locus_tag="KNP54_000465"
     CDS             60846..62783
                     /gene="htpG"
                     /locus_tag="KNP54_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBF0891395.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            63171..64301
                     /locus_tag="KNP54_000466"
     CDS             63171..64301
                     /locus_tag="KNP54_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBF0891396.1"
                     /translation="MNFNYNLPVNILFGSGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            64528..65550
                     /gene="splB"
                     /locus_tag="KNP54_000467"
     CDS             64528..65550
                     /gene="splB"
                     /locus_tag="KNP54_000467"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBF0891397.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            65732..66643
                     /locus_tag="KNP54_000468"
     CDS             65732..66643
                     /locus_tag="KNP54_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0891398.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            66658..67074
                     /locus_tag="KNP54_000469"
     CDS             66658..67074
                     /locus_tag="KNP54_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBF0891399.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(67174..67566)
                     /locus_tag="KNP54_000470"
     CDS             complement(67174..67566)
                     /locus_tag="KNP54_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891400.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            67707..68102
                     /locus_tag="KNP54_000471"
     CDS             67707..68102
                     /locus_tag="KNP54_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBF0891401.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            68505..68711
                     /locus_tag="KNP54_000472"
     CDS             68505..68711
                     /locus_tag="KNP54_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891402.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(69023..69766)
                     /locus_tag="KNP54_000473"
     CDS             complement(69023..69766)
                     /locus_tag="KNP54_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBF0891403.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            69932..72499
                     /locus_tag="KNP54_000474"
     CDS             69932..72499
                     /locus_tag="KNP54_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0891404.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            72729..73133
                     /locus_tag="KNP54_000475"
     CDS             72729..73133
                     /locus_tag="KNP54_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0891405.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            73157..73654
                     /locus_tag="KNP54_000476"
     CDS             73157..73654
                     /locus_tag="KNP54_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891406.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            73657..74058
                     /locus_tag="KNP54_000477"
     CDS             73657..74058
                     /locus_tag="KNP54_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBF0891407.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            74076..74564
                     /locus_tag="KNP54_000478"
     CDS             74076..74564
                     /locus_tag="KNP54_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891408.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            74591..75346
                     /locus_tag="KNP54_000479"
     CDS             74591..75346
                     /locus_tag="KNP54_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0891409.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            75346..76209
                     /locus_tag="KNP54_000480"
     CDS             75346..76209
                     /locus_tag="KNP54_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBF0891410.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            76256..76735
                     /locus_tag="KNP54_000481"
     CDS             76256..76735
                     /locus_tag="KNP54_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBF0891411.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            76800..78107
                     /locus_tag="KNP54_000482"
     CDS             76800..78107
                     /locus_tag="KNP54_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0891412.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            78417..78557
                     /locus_tag="KNP54_000483"
     CDS             78417..78557
                     /locus_tag="KNP54_000483"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBF0891413.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            79067..80161
                     /locus_tag="KNP54_000484"
     CDS             79067..80161
                     /locus_tag="KNP54_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891414.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            80166..80366
                     /locus_tag="KNP54_000485"
     CDS             80166..80366
                     /locus_tag="KNP54_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBF0891415.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            80366..81283
                     /locus_tag="KNP54_000486"
     CDS             80366..81283
                     /locus_tag="KNP54_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891416.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            81280..82038
                     /locus_tag="KNP54_000487"
     CDS             81280..82038
                     /locus_tag="KNP54_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0891417.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTIYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
     gene            82286..83359
                     /locus_tag="KNP54_000488"
     CDS             82286..83359
                     /locus_tag="KNP54_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBF0891418.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            83429..83692
                     /locus_tag="KNP54_000489"
     CDS             83429..83692
                     /locus_tag="KNP54_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891419.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            83898..84875
                     /gene="bioB"
                     /locus_tag="KNP54_000490"
     CDS             83898..84875
                     /gene="bioB"
                     /locus_tag="KNP54_000490"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBF0891420.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            85104..86117
                     /locus_tag="KNP54_000491"
     CDS             85104..86117
                     /locus_tag="KNP54_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBF0891421.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            86159..87049
                     /gene="rbsK"
                     /locus_tag="KNP54_000492"
     CDS             86159..87049
                     /gene="rbsK"
                     /locus_tag="KNP54_000492"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBF0891422.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            87097..88059
                     /locus_tag="KNP54_000493"
     CDS             87097..88059
                     /locus_tag="KNP54_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBF0891423.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            88113..89624
                     /locus_tag="KNP54_000494"
     CDS             88113..89624
                     /locus_tag="KNP54_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBF0891424.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            89608..90606
                     /locus_tag="KNP54_000495"
     CDS             89608..90606
                     /locus_tag="KNP54_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBF0891425.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            90790..92052
                     /locus_tag="KNP54_000496"
     CDS             90790..92052
                     /locus_tag="KNP54_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0891426.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            92072..92815
                     /locus_tag="KNP54_000497"
     CDS             92072..92815
                     /locus_tag="KNP54_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBF0891427.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSKHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            92988..94373
                     /locus_tag="KNP54_000498"
     CDS             92988..94373
                     /locus_tag="KNP54_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0891428.1"
                     /translation="MENLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKYGFSIDELEGMDTAFAASYGEGRPVIAVLGEYDALDSLSQKVSTIKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            94592..95431
                     /locus_tag="KNP54_000499"
     CDS             94592..95431
                     /locus_tag="KNP54_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891429.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            95421..95864
                     /locus_tag="KNP54_000500"
     CDS             95421..95864
                     /locus_tag="KNP54_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891430.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            95875..96366
                     /locus_tag="KNP54_000501"
     CDS             95875..96366
                     /locus_tag="KNP54_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891431.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(96570..97298)
                     /locus_tag="KNP54_000502"
     CDS             complement(96570..97298)
                     /locus_tag="KNP54_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBF0891432.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            97423..98511
                     /locus_tag="KNP54_000503"
     CDS             97423..98511
                     /locus_tag="KNP54_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891433.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(98948..99796)
                     /locus_tag="KNP54_000504"
     CDS             complement(98948..99796)
                     /locus_tag="KNP54_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891434.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGIPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            99995..100360
                     /locus_tag="KNP54_000505"
     CDS             99995..100360
                     /locus_tag="KNP54_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0891435.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            100383..102770
                     /gene="cadA"
                     /locus_tag="KNP54_000506"
     CDS             100383..102770
                     /gene="cadA"
                     /locus_tag="KNP54_000506"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBF0891436.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKAYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
BASE COUNT        41667 a        10605 c        18830 g        32108 t
ORIGIN      
        1 ggtagtagtg gcgaagacac cgtccgaagt agcttggctt tgtaaccacc tctgttgtac
       61 tgtttaagta taaataagtg tgttagccac caagaatccc cttgctttag ctatggggag
      121 tgtgtcaata aaatacttta atgaaaaata gctaacttta attgtaggat attcttaata
      181 tatttgaaat aaataaaaat attgaaggat ataatattca actggtatat aaataataaa
      241 tgatagttaa attttacctt agaggctaat taggtgttta gtcaaagcta atgcctttag
      301 aatacaaatg tattctaaag gcatttttac tatgtatttt catttatatt actaaacatt
      361 atctattttt atatacattt ctatgtattt tattttcatc aaatcggtct ataaactcat
      421 ttttttcttc actatatcca atagatataa gtgcataagg aactaatttt aatggtaagt
      481 ctaaagtttg tctaacttta tttaccactt tatttttagg aaatactcct gcccaacaag
      541 cagctagacc ttgattagta acttctaata ataaattttg tgtgcaagca cctaaatctt
      601 gtatccattt accaggtttt aagaatttat ctctatttcc aagcactact atacataatg
      661 gtgcaaattc tatatgcttt gctctatgct gtgactttga gagctgtttc agcagttcct
      721 tatcatctac tataataaat tcccaaggtt gagcattttt tgatgaaggt gcttgcatag
      781 ctgattttag tatttcagtt attttatctt cttctatatt tttatctata tatgttctta
      841 ttgaacgtct attttttata acttctaaca tacagattct cctttaaata aaattatttc
      901 tatttatata atatcattac tttaaatttt agctattact tatataaaga ataaactttg
      961 tgttggtttt atctaagtaa aagtaacatt cagaactaaa aaacaagact ataaatccaa
     1021 agtattaatt aaaaaagaag taataaaaaa taatatacaa gatttaaaaa agagtattgg
     1081 gcttaaaatt taattagaaa accaattttg agataatctg ttttttattt taacaaaaaa
     1141 acataaataa agttcgatac gtagcgaatg aaaaaattac aagaaatatt ttttttaaaa
     1201 aatttcaaaa aagagttgat aatatatgta tattaatata aaatttaagg tgtataattc
     1261 gtataataat acgaatgatt tgtagtgtaa aataacttat aaacggagag gggaagtcta
     1321 atgaaagtag cagtagttat gggttcaaaa tcagattatc caaaattaga agaagggata
     1381 aaactgcttg aaaaatatgg aatagaagtt gtagcaagag cattatcagc tcatagaaca
     1441 ccagaacaac tttcaatatt cctaaaagaa atagaagatg atactgatgt aataatagca
     1501 gcagcaggaa aagcagcaca cttaccaggt gtaatagctt cacaaacatt aattcctgta
     1561 ataggattac ctattaaatc atcaactatg gatggactag actcactttt atcaatagtt
     1621 caaatgccaa aaggaatccc agttgcaaca gttacaatag acttaggttt aaacgcagct
     1681 ttattggcat tacaaataat gactttaaaa tacccaaaat taaaagagga tttgaaatca
     1741 tatagagaag agatggcaca aaaggtgtta gaagacgaca ataatttaag ggggtagcag
     1801 aaatgttatt atatgaagga aaagcaaaac aagtatattc tacagataat gaaaatgaat
     1861 atgttgttta ttataaagat gatgcaacag catttaatgg agaaaaaaaa gcagaaatat
     1921 cttcaaaagg tatactaaat aataagatat caacaataat ctttgaaatg ttaaaagaaa
     1981 ataatataaa tactcacttt ataaaaagtt tatcagatag agaaatgtta gttaaaaaag
     2041 tagagatttt accattagaa gtaatagtaa gaaatattgc tgctggttct atctgtaaaa
     2101 gagttggtct tgaagaaggt gtagttttcg atgagccaat ttttgaaata agctacaaaa
     2161 atgatgctta tggtgaccca atgctaaatg atgattatgc agtggcaatg aagttagcaa
     2221 ctagagaaga gttaaaattc ttaagagaag aaactttaaa aataaatgag ttactaaaag
     2281 catttttctt aaaattaaac ctaaagttag ttgactttaa aatagaattt ggtaaggatt
     2341 ctgaaggaaa tataatattg gcagatgaag tatcaccaga cacttgtaga ctttgggatg
     2401 taaatacaaa tgaaaagtta gataaggaca gatttagaaa agaccttgga gaccttgtag
     2461 aaggttatac ggaagtactt tcaagaatga ataataaata ggaggcaaat gtatgtgtgg
     2521 agttttaggg atttactcta ataaagatgt aactaaagaa ctatattatt ctttatattc
     2581 tatgcaacac agggggcaag aaagctgtgg tttagctctt ttagatgatg gagaaattaa
     2641 gtacaaaaaa gatatgggat tagttggaga tgtttttaag gaaaatgaat tatctaagtt
     2701 aaaaggaaat atagggattg gacatgttag atattcaaca gctggaggaa gtcatgtttc
     2761 taattgtcaa cctttagttg gaagttgtag aaaaagacaa ttagccatag ctcataatgg
     2821 aaatctagtt aatgcaaatt atttaaaaga tatgctagaa gaagatggat atatgttcca
     2881 aactaattca gatacagaag tgattttata tatacttgct agatattaca aaggggatat
     2941 agtagaaagt ttaaaagtga caatggatta tataaaaggt gcatatgctc ttgtaataat
     3001 gagtcaagaa gaattggttg cagttagaga cccacatgga ttcagacctc ttgtacttgg
     3061 taaaaagggt gatgaatata tatttgcatc agaaaattgt gcaatagata tacttggcgg
     3121 agaagttata agagatgtag agccaggaga gataatagta gtcaaagatg gagaactaaa
     3181 atcatatttt tattcagaaa attataaacc agttaagaaa agttgtatat ttgaacacat
     3241 atactttgca agaaatgatg caactataga caatgtaaat gcatatgaat ttagaattaa
     3301 atgtggtgag agattagctc agaatgaaac tgtaaaggca gatatggtag ttccagttcc
     3361 agattcaggt tggccaggag ctattggtta tgcaaatgct agtggattaa aaataagtga
     3421 aggcttagtt aaaaatagat atgtaggaag aacatttata aaacctacac aagaagaaag
     3481 agaaatagca gtaaaaataa aattaaatcc tctttcaaca ataataaaag gaaaatctat
     3541 aattttagta gacgactcaa ttgtaagagg aactacatct aaacaattag taaaatcttt
     3601 aagagaagca ggtgcaaaag aaattcatct tagaataact tctcctccag tagcttactc
     3661 ttgttactat ggaatagata ctccaaatcg ctctaaatta attgcatcaa gtaacaacgt
     3721 agaagaaatg agagaatata ttggatgtga tagtttaaaa ttcctagata tagaaggaat
     3781 gttagatgca acagaacata agtctacttt ctgtaaagct tgttttgatg gagaataccc
     3841 agttaagaaa attgataagg aggaactact ttcatgttaa catataaaga atcaggtgta
     3901 gatatagatg aaggaaatag agcagtagac cttataaaag gtaaaataaa aggaacttat
     3961 gatggaaatg tagttggaga tttaggtaac ttcagtggat tatacagttt aaaagatttt
     4021 gtaggtatga aagaaccagt tttgcttgca tctacagatg gtgttgggac taagttaaaa
     4081 atagctcaga tgatggacaa gcatgatact gttggaatag atttagttgc aatgtgcgtg
     4141 aatgatttaa tttgtcaagg agcaaaacca ttattcttcc ttgactatat agctcttggg
     4201 aaattagtgc ctgagcatat agaaaaaata gttggtggaa ttgcagatgg ttgcaaaatg
     4261 tctggttgtg cactaattgg tggagaaact gctgaaatgc ctggaatgta tggagaagat
     4321 gactatgatt tagcaggatt ttctgtggga atagcagaca aagaaaagat tgtttctgga
     4381 aacaatgtta aatcaggaga tgtattggtt ggtatatctt caagtggagt acacagcaat
     4441 ggattttctt ttataagaaa gatattttta gaaacttaca attataaaat ggaacgatat
     4501 gttgaagaac taggaatgac agttggagaa gcacttttaa caccaactaa aatatatgtt
     4561 aaattagctt tagatgtatt agctaaacat gacataaaag ctgtagctca cataactggt
     4621 ggagggctta tagaaaatat aacaagagtt atacctaaag gattaggact agatatcaat
     4681 aaaaaatctt gggagaagcc tcctatattt aaaatgatag aaggttttaa tgctgttgat
     4741 gagagagaac ttcataagag ttttaacatg ggtattgggc tagttttaat agtagataaa
     4801 gaaaatgctg atgatgttgt aaactttata aataatagag aaaatgacaa tgctgattat
     4861 gtagataaaa aatatagtga attattagaa gataaagctt atataattgg tgaagtagta
     4921 gatagtcatg aaggtgtaga attatgctaa atataggagt tttaatatct ggtgggggaa
     4981 caaatttaca agcagttata gatggtactg agtctggaga aataaaaggt caggttaaag
     5041 tagttatctc aagtaagcaa ggtgcttatg ggctagagag agctaaaaat cataacataa
     5101 aagcaatttg tgaaactgat gaagacaaga taatagaaat tcttaaggaa aataaaatag
     5161 atttagtagt tttggctggt tatttaaaaa taatcagccc aaagctggtt aatgagttta
     5221 gaaacaaaat gataaacata catccatcat taattccttc attttgtgga gctggattct
     5281 atggagaaaa agttcatcaa ggtgttatag attacggagc taaagtaact ggtgctacag
     5341 ttcattttgt tgatgaaggt gctgatactg gaccaatcat aatgcaagat gtagttaagg
     5401 taaatcaaga tgatgatgca aagacacttg caaaaagagt gttagaagtt gaacatagga
     5461 ttttaaaaga aagtataagt cttttttgtg aaaataaatt aaaacttcaa ggtaggagag
     5521 tgtttataaa tgagtaagag agctttaata agtgtaactg acaagactgg tgtagtggaa
     5581 tttgctaaag agttaaataa attagattat gaaattatat ctacaggaaa tacatttaaa
     5641 acattaaaag aaaatggtgt taatgtaatg caagttgaag atgttacaaa ttttccagaa
     5701 atattagatg gaagagtaaa aacattaaat ccatatatac atggtggtat actttataaa
     5761 agagataaag aatctcatgt agaaactgta aatgaacata aaatacattc aatagattta
     5821 gtagctgtaa atctatatga ttttgaagga actttaaaag ctggaaaaag tcatgatgaa
     5881 ataattgaaa atatagatat tggtggacca tctatgatac gttctgctgc caaaaactat
     5941 aaggatgtaa tagtagtagt agatataaaa gattatgatt ctataataga aaaattaaaa
     6001 acagatacaa tgacattaga agacagaaaa aaattatcat ataaagcttt ctcaactaca
     6061 ggaagatatg atgcgttaat atctagttat tttgctggag aagttggaga tacgtatcct
     6121 gacatattaa atttaacttt ccaaaaagaa caaactttaa gatatggaga aaatccacat
     6181 caaaatggtt tcttatattc acagtcaaat gcaaaaaatc caatcttaaa ttatgagcaa
     6241 ttaggcggta aagaactttc ttttaacaac ttaaatgatt tacatggatg tttagaagta
     6301 atgagagaat ttaaagatag tgaagaagta gtttcagtag ctataaaaca tgctaattca
     6361 tgtggggtag gtttaggaaa agatgctttt gaagcatata caaaatgtta tgaagcggat
     6421 aaggtttcaa tatttggagg aatagtagga ataacttcta ctatagataa agctacagca
     6481 gagaaattaa atgaaatatt cttagaaata gtagtagcat atgattttga accagaagct
     6541 ttagagatac ttaaacaaaa gaaaaatcta agaatattaa aattagctaa aatagaaaat
     6601 agtttacaac catatgaaat gaaatattta gatggaaaat tattgataca agatagaaac
     6661 aatatattag cagaaaaaag tgaaaatgta acaaaggaaa aaccaacaga tgcacaactt
     6721 aaggacatgg aatttggtat gagagtagta aaaaatatga aatcaaatgc aattgcaata
     6781 gtaaaaaatg gacaaactct agctttaggt tgtggacaaa catcaagaat ttgggcatta
     6841 aaaaatgctc ttgaaaataa caaagataaa gattttacag gagctgtttt agcgtcagac
     6901 gcatttttcc catttgatga ttgtgtaaca ttagctcatg aatatggaat atcagcagta
     6961 gttcaaccag gtggctctat aaaagataaa gattcaatag aagcttgtga caagtatgat
     7021 atggttatgg tatttacagg aataagacac ttcaaacact aaggaggata ttatgaagat
     7081 attggttgta ggcggtggcg gaagagagca tgctatatgc tggaaactaa gcaaagaaaa
     7141 aaatgtagaa aaaatttatt gtgcaccagg taatgcagga attgcaaacg tagcagaatg
     7201 tgtaaatata ggtgatacta atatagaaga acttttaaaa tttgccaaag aaaatgaaat
     7261 aggtctgaca atagtaggac cagaagtacc actagttatg ggaatagtag atgagtttga
     7321 aaaagaagga ttaagagtat ttggacctaa taaaaaatgt gctcaacttg aaggaagtaa
     7381 agctttttca aaagaattta tgataaaaca taacatacct actgcaaaat ataaagaata
     7441 tacaaactta gaagaagcta tatcagaaat agatagtttt ggatatccag tagtaataaa
     7501 agcggacgga ttagctgctg gaaaaggtgt tgtaatacct gaaaatagag aagatgctat
     7561 agcaacttta aaagaaatga tgtcagataa gaagtttgga gctgctggag ataaaatagt
     7621 aattgaagag tttttaaaag gaatagaaac ttcaattcta gcatttgtag ataatgatac
     7681 aatagttcct atggcaagtg caaaagacca taaaaaagta aacaactatg agcaaggtcc
     7741 aaacactggg ggaatgggaa ctttttcacc tagtgaaata tatacagaag aattagcaaa
     7801 taaagtaaaa gagacagtat tagaaaaaac tttagaaggc ttcaaaaaag atggacttaa
     7861 ttttaaaggt attttatttg ttggtcttat gataactgaa gatggagaaa aagtacttga
     7921 atataatgta agatttggag accctgagac acaatctgtt ttatttagat tagaaacaga
     7981 tttacatgag ataatggaag ctatactaga taataagtta aaagatatag aaataaacta
     8041 tagtgatgat gaagctgtat gtgttatgct tacatcagga gggtatccag acagttatga
     8101 aaaagggaaa attataactg gtcttgaaaa cttggatgat gatatagtag tattccatag
     8161 tggcactaag atgtttgatg gtaatttggt taccaatgga ggaagagtaa ttggtataac
     8221 tgcaaagtca actacagtta aggatgcagc agaaaaagtt tatgaaaaca taaagaagat
     8281 aaactttgaa ggaatgcact atagaacaga cataggaaga taatttttct aaaatggagg
     8341 ataaggtatg ttgaatactg aaaataaaga ctcaatggtt agaagagtat tagttgaaaa
     8401 aagagaaggt tttgaccttg aggctaaagc tttaaaaaaa gacttagtag aaagtttaca
     8461 catagataat atagaaaatt taagaatatt aaatagatat gatgtagaag gaatatcaga
     8521 agaagtttat gaaaatgcag caaagacaat attctctgaa ccaaatttag atgtagtata
     8581 ttatgaagaa ataccaaaat taaatgatga aagagtattt gcaatagaat ttcttcctgg
     8641 tcaatacgac caaagaggtg attgggcagc tcaatgtgta caaattgtaa atcaagggat
     8701 aagacctgct attaatacag caaaagttta tatattatca ggcaaaataa ctgatgaaga
     8761 gttttctaaa ataaaagatt actgtataaa tccagtagat agtagagaag catctttaga
     8821 aaaaccagaa acgttaaaaa tggaaactga aataccaaca acagttgaag tattagatgg
     8881 atttatagat ttagatgaaa atggattaaa aacatttgta agtgaaaaag gattagcaat
     8941 gactttagga gacttacaac acgttcaaaa atactttaaa gatacagaaa agagaaatcc
     9001 aactataaca gaaataaaag tattagatac ttattggtct gatcattgta gacatactac
     9061 ttttatgact gaaatagaaa atgtaaagat agaagatggt aagtttaatg atatagtaaa
     9121 agaagcgtat caaatgtatc ttaactcaag agacaatgta tatgtgaaca gacataaaga
     9181 tatatgttta atggatatag ccactgttgc agtaaaagaa ttaaagaaaa atgggaaatt
     9241 aaatgaccta gatgaaagtg aagaaataaa tgcatgtagt ataaacgtag atgttgaagt
     9301 tgatggtaag atggaaaaat atctagtaat gtttaaaaat gaaactcaca accatccaac
     9361 tgaaatagaa ccatttggtg gagcagctac ttgtttagga ggagctataa gagacccatt
     9421 atcaggaaga agttatgttt atcaagcaat gcgtgttaca ggaagtgctg acccaagaac
     9481 gactttagaa gatactttac ctggaaaact tatgcaaaga aaaataacta cagaagctgc
     9541 tcatggatat agttcatatg gtaaccaaat aggtcttaca actggacaag ttgcagaagt
     9601 atatgatgaa aactttgttg caaagagaat ggaaataggt gcagttatag cagcagcacc
     9661 aaaagagaat gtagtaagag aaagacctga agcaggagat gtaatcgttc ttcttggagg
     9721 aaaaacagga agagatggct gtggaggagc aactggttca tctaaagaac atagtgaaga
     9781 gtcaatctta acttgtagtg cagaagttca aaaaggagat gctcctaacg aaagaaaaat
     9841 acaaagattc tttagaaata aagaagttgc tcaaatgata aaaagatgta atgattttgg
     9901 agcaggtgga gtttgtgttg ctataggaga gattgctgat agcttagata taaacttaga
     9961 cttagttcct aaaaaatatg atggacttga tggaactgag cttgcaattt cagagtcaca
    10021 agagcgtatg gcagtagcca taaaaaaaga aaataaagat aaatttatac aattagcagt
    10081 agaagaaaac ttagaagcta cgcatgtagc tacagtaaca gatacaggat atttaagaat
    10141 gttctggaat ggaaaagcaa ttgtagatat aaatagagag tttttagata caaacggagt
    10201 aaaacaaact actgatgttc atgttactaa agtagatgaa gaaaatacat tctttagctc
    10261 taatgaaata gtaaaagatg ttaagtgtgc aagtatgaaa gacaagttta caaaagtact
    10321 atctgacctt aatgtttgtt ctcaaaaagg attagtagag atgtttgata atacaattgg
    10381 tggtaataca gtacttatgc catttggagg aaagtatcaa gcgactccaa cacaaggtat
    10441 ggttgctaag ataccagtac ttggaggaga aactaatact tctacaataa tgacttatgg
    10501 atacaatcca aaggtaggaa aatggagccc attccatggt gccttgtatg cagtagtaga
    10561 atctgtgtgt aaattggttg ctattggagg aaattatagt acaacaagac ttacattcca
    10621 agagtatttt gaaaaacttg gtaacaatcc agaaaaatgg ggtaaaccat tctcagcact
    10681 tttaggagca ttttatgcac aaagtaaatt tgagatacct gctataggtg gaaaagacag
    10741 tatgtctggt acatttaaag atattgaagt tccaccaaca ttagtttcat ttgctgttga
    10801 cacagtagat gcgaagaaag tagtatctcc agaatttaaa aaagcagact caaaagtagt
    10861 aatgttatgt gtaaacaagg cagaaaatga tgttgtagat tttgaggaat taaagagaaa
    10921 cttagataaa gtaagagaac ttatacatgg aaataaagtt ttatcaacat atgcattagg
    10981 atttgcaggt gtaggtgaag caataagtaa aatggctttt ggtaataaaa taggatttaa
    11041 gtttagtgaa gaggctgaaa aagcatttac agatgataaa ttatttgagg ctagttatgg
    11101 aaatatagta cttgaattag caaatgatga tttaagtatg ttagaaggat acaattatgt
    11161 tgtgcttgga agtacagtta aagaaactag tatatttatc aaaggtgaag aacttgcatt
    11221 agatgaatta tataaagcac attgtagtac tttagagcct atattcccaa ctaaaacaga
    11281 agaagtaaaa tcaaagatag aaactataag ttatatatca caaggagaag ctaaaaaatc
    11341 atcattaagt atagctactc caagagtatt tataccagca ttccctggaa caaactgtga
    11401 atatgactct gcaagagcat ttgaaagagc aggagctaat gcaagtataa gagtatttaa
    11461 gaatttaact tataaagaca tagaagattc tatagataca atagtaaacg aaataaaatc
    11521 ttctcaaata ataatgttac caggtggatt tagtgctggt gatgagccag atggttctgg
    11581 taaatttata gctactgtat ttagaaatcc tagagtgcaa gaagctataa atgaattttt
    11641 aactcaaaaa gatggactaa tgttaggtat ctgtaatgga ttccaagtat taattaaatt
    11701 agggttagtt ccatatggag aaataagagt tccaagtgaa agtgctccaa cacttactta
    11761 caataatatt ggtcgccatc aagctaagat tgctagaact agaatttcat ctaataaatc
    11821 tccttggtta gctcaaacta atgttggaga tattcataat atagcaattt ctcatggaga
    11881 aggtaagttt gttgccagtg aagatgttat gagagaatta attgctaatg gacaagtagc
    11941 aactcaatat gttgacttta ataatgaagc tacttatgat attgagttta atccaaatgg
    12001 ttcattctat gctgttgaag gtataactag tgctgatggt agagtgtttg gtaaaatggg
    12061 acattctgaa agaattggtg aggaagtata taagaatatt ataggtgaaa aagaccaaaa
    12121 gatatttgaa tctggagtta aatattttag ataaagcttt gatgtttaat tgatagctag
    12181 aatatataat ttagatattt agatttaaag agatgtaata atatgatgat aatcatttaa
    12241 tattacatct cttttttatt tatctaagaa ataataagtt caacctaagt taaaatacaa
    12301 gctgtgttat aattaattat taagtaaaat tgaatattta ttggaggaca acataattaa
    12361 tgaaaatatt aataacaggg tctaatggtc aattaggaaa agaattggtt aaccaattag
    12421 aagcaatcaa tcaaagtata aaccaaccaa aatatgttat attagctaca acaagaagtg
    12481 atttggacat atccaatcag actaatgtag ataattttat tttgcataat aaacctgatg
    12541 tagttgtaaa ctgtgcagca tatacaaagg ttgatgcatg tgaagataat atcgaaattg
    12601 catacaaaat aaatgcttta ggagtgagaa atctagcaat agcatcagaa aaagttaatg
    12661 ctaagcttat tcacatatca actgactatg tattcaatgg tttttctaaa tatccatata
    12721 gggaagacaa taaaactgaa cccaattctg tatatggaaa aagtaaactt atgggagaaa
    12781 aatttgttga acaattctca cataagtact ttatattgag aacagcatgg ttatatggta
    12841 atgggaataa ttttgtaaag accatgataa aactttcttt agaaaataaa gaggttaatg
    12901 tggttaatga ccagtttgga actccaacaa gtacagtaga cttagcaaaa attataataa
    12961 aaatcatgga aacagaacat tatggagttt atcatgctac atgtgaaggt gagtgtagtt
    13021 ggtatgattt tgccaaaaag atatttaaac taaaaaatat agatataaaa gtaaatccaa
    13081 ttaagagtaa cgaatttaaa tgtaaggctc caagaccact atattctgta ttggataatt
    13141 ttatgttgaa gttaattggt ttaaattctt ttagaaagtg ggaagaatcc attgaagaat
    13201 atttagaaag atatgatata aatgaaaagt aaatgtatta ttttgagaaa agaaaataag
    13261 atattataaa aaatataaat atttctttta tttatccgat aatcataata tgacaaaaac
    13321 aaatttaagg atggaaaaag atgaaaggaa ttattttagc aggagggtct ggtacaagac
    13381 tatatcctat aacaaaatgt atatcaaaac aaacacttcc aatatacgat aaaccaatga
    13441 tatattaccc tatgtcggtt cttatgttgg cagggataca agatatatta ataatatcta
    13501 caccaagaga tataaaagca tttgaagaat tatttggaga tggaagttca ctagggctta
    13561 acataacata tgcaattcag gagaaagcaa atggaattgc agaagcgttt ataataggag
    13621 aagaatttat aggaaatgac agagtgtctc ttgtattagg ggataatata ttttatggat
    13681 atggatttag tgaaaggttg gagaatgcag ttaaaagaaa aggagcaact atatttgggt
    13741 atcatgtaag taatccaaat tcgtttggag ttgtagaatt tgataaggat tttaatgtat
    13801 tgtcaataga agaaaaacct acagttccta aatctaatta tgctatacca ggattatatt
    13861 tttatgataa tgatgttgta gagatagcaa agctagttga accgtcagat agaggtgaat
    13921 tagaaataac ctctataaac agtgaatatc taaaacgagg aaaactaaaa gtggaacttc
    13981 taggaagagg tatggcttgg cttgatactg gtacacataa aggtctattg gatgcttcta
    14041 attatgttga agtggttcaa acaagacagg gactgtatat agcatgttta gaagagattg
    14101 catatacaaa aggatatata agtagagaac aattaatgaa actagccaag ccactgataa
    14161 aaactgaata tggtcaatat ctattaaaat tggctagtga agatatgtaa tatggtagat
    14221 aaaatttatt ataaatttta ttaagggagt ttattataat gggaaaaatc aatgttataa
    14281 agactaaaat agaaggatta tatatagtcg aaccaaatgt attttatgat gaaagaggat
    14341 attttatgga aagctataat aaaaaggatt ttatagagca gggtcttgat atgtgtttta
    14401 ttcaagataa tgagtctagc tcaagaaaag gcgttttaag aggaatgcat tttcaggtta
    14461 aatatcctca aggaaaatta gtcagagtta cagagggaga agttttcgat gttgcagttg
    14521 atttaaggaa agattcacaa acatttggga aatgggaagg tgtaatattg tctgataaga
    14581 ataaaaaaca attttatatt ccagaagggt ttgcacatgg atttttagtt ttatcagaaa
    14641 aagcagtatt tagttacaaa tgtacaaatt attattaccc agaatttgag aatggcttta
    14701 tatggaatga caagcaaata tctattgagt ggcctttaaa aggaattgaa gaaatatttt
    14761 tatcagaaaa ggacaaaaaa caaaaaagtt ttaaagatat ttgtacaaga cgttaataaa
    14821 aatttattag aattaacatt taggagaaaa aatatgaaaa aaatactgat aactggagga
    14881 gcaggattta ttgggagtaa ttttatacat tatatgctta acaagtatgt agattatttt
    14941 attgttaacc tagacttgtt gacttatgct ggtaatttag agacattaat agaaatacaa
    15001 gacaattcca attataaatt tgttaaagga gatatttcaa atagggagca ggtgtataag
    15061 ctatttgaag aagaaaggtt tgatatagtt gttaactttg ctgctgaatc tcatgtagat
    15121 aggtcagttg agaatcctga tttatttatt aaaacaaaca ttataggaac acaagtactt
    15181 ttagatgcat ctataaaata tggagttaaa aggtatcatc aaatatctac agacgaagtg
    15241 tatggtgatt taccaattga tagaaaggat ttattcttta cagaacaatc ttctatcaat
    15301 ccaagttctc catattcagc ttctaaagca tcagcagatt tattggtaag ttcttattat
    15361 agaacatatg gattgttaac aactatatct aggtgttcca acaattatgg gccatatcat
    15421 tttcctgaaa aattgattcc tcttatgatt ttaaatgctt tggaaaacaa acaattgcca
    15481 gtatatggga atggggaaaa tgtaagagat tggttacatg tatatgacca ttgtactgct
    15541 atagacttaa taatacataa aggaaatata ggggagattt acaatatagg aggtcataat
    15601 gaaagaagta atctagaagt agtaaaaatg atattaaatc ttttaggtaa atctgaagag
    15661 ttaatatcct atgtaaatga tagacctggt catgatttaa gatatgctat tgatgcaact
    15721 aaaatagaga atgagttagg ttggaaggca aaatatgact ttgatttggg tataaaagaa
    15781 actgttaagt ggtatataga aaatgaatct tggtggaaag ctgttttatc agtataactt
    15841 taaaatttag aaaggggcgt tttatattga atgagataag ttcactaatt aatatattag
    15901 cattgactca attatctggt agtaatacta caaatcaatg taattgtaca tataataatt
    15961 catctggatt tgatatgatt atgatgacct tgttaaaagc attatcacaa aataatcaac
    16021 atacttctaa tagctacaat ttattgtcta attctgagaa tttatttaat gaacttgata
    16081 atgtagtaaa taataccact agtagattta tagatgttga tacaaaagat aaaaatgtaa
    16141 agttgagaat tgaaaatgct gtaaatcaag catcaaaaaa atataacgta gattcaaatc
    16201 ttataaaagc aataattaaa gttgaatcag attttaatcc aaataccgtt tcttctgctg
    16261 gtgctaaggg tcttatgcaa cttatgccag aaaactgcag agacttaggg gttacagacc
    16321 cttttaatat agaacagaat atagatgctg gaactagaca tattaaggaa tacattgata
    16381 tgtttggagg gagcatagaa atgggattga tggcatataa tggtggtcct ggaagaatga
    16441 aaagtagagg agtagaatca atctctgacc tgtataaaat gccaaaagaa acacaaaatt
    16501 atattcctaa ggttatgaaa tattatagag ggtaggcttt attatgggaa taaatataga
    16561 taagctaaac ataagtccaa gtataaatat ggaggttaaa aaactaaaag agagtaataa
    16621 attttctgac aaattaaact ctttaaaaca atcttcttca ttggaagata taaaacgaaa
    16681 tttggaaagt gtaaaaaagg caggagaaag gcttgtactt actcaaaact atggcgatat
    16741 tagtatatat aaaaatgcag taaaagaata cctaaaatct gttgtagata atatgtattc
    16801 acttgataaa aatagtagct tttgggagca tcagtattat aagaatgtaa agattgttga
    16861 tagtaaactt gaggatatga ctagtaagtt aattagtgaa gaaaaagaaa acatagatat
    16921 tgtttctact gttgacatga tacaaggctt attgatagat atgtatagat aaggttatac
    16981 aaggagaaaa attttatgaa tagcaaaaaa gaggatatat atgaattgaa ttttgggcaa
    17041 ttaatagaag aaaaatctgg tgttatagaa gaaaatcaaa atgtttttaa tgcaaaagta
    17101 aaggtagctg tttctatagg aaatacaaca gaaacaataa aaaatatatt agatttaaaa
    17161 gaaggctcta taataaaatt aagtaagaat gtggatgaaa aattagatat atatgcaaac
    17221 gatagattgt ttgcttatgg agaaagcatt attacaaatg agaagttatc tgtaagatta
    17281 tctaaaatag aagattcaga tgtaaattag cattttaaat atatcccttt agtctattct
    17341 gtatgagttt agctaagggg atatttttat aaaaaattta aaatatgtgt gaattatata
    17401 aatattttta ttttatgagc gataactaaa ttataagtat gtaattttgg aggtgaaact
    17461 atggatatta aaaatgtaag ttcaaatatt gtagtgaata attatttaaa gaatacatct
    17521 ggtataaaaa aagtggaaga ggttaaaaaa attaataaaa cagacaagat agagttatct
    17581 aaatttgcaa aggaaatggc aagtgtgtca aatatgagtg atgagaatat tagaaataaa
    17641 aaagtcgatg aaataaaaaa tgcattagaa aatggaactt acaaaataaa accaaaagaa
    17701 attgcgaaaa aaatgataga ggatatgcga ggataaagtc atgattacag acttaaaagt
    17761 tataatatat gaagaaaaaa atataattag taagatgatg gaattattaa aagaacaatt
    17821 tgattatata gttgaaaaag acttagaaaa tttaaatatg ttaaatccta aactagaaga
    17881 tattagcagg gagcttgcat ccatagaaat aaagagaaga caactttttg gtaatgatat
    17941 ttcaatgagt gaagttgttg aaaatagtaa tgatggatat ttaaaagaaa tatatacaga
    18001 cttgaaacgc attcttgctt tagctaaaaa tcaacaagaa tcaaatgatt ctctaataaa
    18061 gaaagaactt atttttacga aaaaaatgat taatttcata aaaccagctg ataagcaaac
    18121 tacaacttat aattcttatg gaaatattag aaaataaata ttaggaggag aaatatggca
    18181 ggattatttt ccattttaaa tacagctaat tcaggaatga atgcgcacca aaaagcaata
    18241 cagacaattt ctcataatat aagtaatcta gatacagacg gttattctag gcaaaggacc
    18301 gagtttgcta caaatagtcc aatgtatatg cctagtttga gtaattcaat tgcaagagga
    18361 caattaggga ctggagtaca tgtaacggat gtaacaagag ctagaaatag tttttatgat
    18421 taccaattta gggcagaagc tcataagtat ggtaagacag tttcaaaata tgattattac
    18481 aatactatag aaactatact aaacgaacca tcagactatg gaatatctgc aggtatagat
    18541 gattttttta aaggatggga gtcattatca aaggatataa atagtgacag taaaaaaagt
    18601 ctagtggtag aaaacgcatc taatttagca actttaataa gtgaaagtta taagaagctt
    18661 gataagttaa aagaagatat agattctaat atagacactg agataaaaca aataaatgac
    18721 atgttaaaaa gtcttgaaga tttaaataaa tctattgata ttatatctgg ttctggctct
    18781 acaccaaatg atttgcttga tgaaagagat agaattttag ataacttgag ttttaaacta
    18841 gactttgaaa atagtgatgt taaaaatatg cttgcagatg gtaaattaga acttaatgaa
    18901 ttaaaaaatc cagatggaac ttggaaaaca ggtatatcag ggaccttaca aggcttgttt
    18961 gaaatgcatg gtaagattga tacatataaa agcgatttaa aagatgtatc tgatggatta
    19021 gctaaacaga taaatgatgt ttataatacg tctgcaggaa taacagtaac agattttttt
    19081 ataacttcaa atgtagatgg tgaagatatt ataaagataa atccagctat aaagagtaac
    19141 ccaaatgaat taaagcttac tgctgatgaa gcttcaaaaa ttgctaagtt aaaggatgaa
    19201 aaaatagata ttggggtggc tggtggaaaa gtaagtacaa taagtgacca ctataaagcc
    19261 tttgcagaat caatcggttt agattctcaa aaagtaaatc aagatgaagc aaatcaacgt
    19321 aaaattataa ataatattga taactcaaga atgagtgttt caggtgtatc tttggatgaa
    19381 gaaatgacag agcttataaa aatacaacgt tcatatcaag ctagtgcaaa agttatgtca
    19441 acagctgtgc aactactgga tgttgtaata aatggaataa tttaatagaa gggggaattt
    19501 ataatgagag tcagtacagg tatgatgtct agcagctatc taaactcact acaagataat
    19561 ctacaaagat tggataaggt taatagacaa gttaatacaa caaaagaaat aaacaagcta
    19621 tcagataatc catataaagc aataaagata ttaaactcaa aaagtgaaat aaagactatg
    19681 gagacttatg ttgagaattg taaagataca gggaattggt tagaaactac tgatactgca
    19741 ttagatcagc ttggaaaatt attatcagac ataaagaaaa ctttggtggc aagtggtgat
    19801 ggtgcatact cagatgatga attaaagact cttagtaatg aaactaatga aaaaatgaaa
    19861 gaaattgcaa atgctttaaa tgcaacacat gaagggaagt acatattttc aggttcaaat
    19921 acgggggtac cacctgttga atgtatagat aatgctgatg gttcagtgag tttaaagttt
    19981 aattctagtc taaatcttaa taaattaaat gactctttga gtatggatat agctcaagga
    20041 ataagtgtag attataacgt taaattgagt agccttggat ttgacccaac aaaaactgac
    20101 ccatttgaag agttaaataa catatcaaaa aaattagcaa atccagatgc tgatgctata
    20161 aaagagctta caacaacttg tttgggcgat atggaacaac taatagaaaa tacagtaaat
    20221 gttaggtcta tatatgggac aaaagcaaat acagtagagg ctatgaagga aaaaaacgat
    20281 gatagtttga tacagttaaa ggatattttg tcacaaaatg aagaaataga ttatggtgaa
    20341 aaacttgttc aattaaaggc agcagagtta acttatcaag cttcactaca aacaggagga
    20401 aagttattta atgtatctat attagattac atataataaa ataacgcaga tatgatgaag
    20461 gttacattaa aaaaaggtat attaggtttt gaaaatttaa aagaatatga gcttttagat
    20521 atagaagata atgattattt aaaagaattt aattctactg aagaagaagg tataggattt
    20581 gttgttgtat ctccatttga gattatcaat gaatatgaaa tagttttaaa tcaggaaaca
    20641 atagaaaaac tagaagtgaa atctccaaag gatgttgtat tatttaatat aattactctt
    20701 ggtcagacat ttgaagaatc aactgtgaac atgaaagctc ctatagtgat aaatataaaa
    20761 actaattttg gaatgcaaat aattttacag gatgataaat attcaataag gcatccatta
    20821 ttgagaggtg ataatggatg ctagtaattt caagaaaaaa agatgaagca gtacttatag
    20881 gagaaagcat agaagtaaaa attgtaggag tagatggaaa caatgtaaaa ctagctatat
    20941 cagcgcctaa caatataagt atattaagaa aagaaatata cgaaaaagta aagagtgaga
    21001 atataaaagc tacaaataaa aatataaaaa ttttaaagtc attaaaataa taagcttgga
    21061 ggaagtaata tatgtatgga gaaaatcctt ataattctta taaacaaaat gctgttttta
    21121 tggcatcaaa ggaacaattg ttacttatgc ttgttgatgg agcagtaaaa tataccaaaa
    21181 tagccagagc agctatctta gataaaaata cacagaaagc gcatagagaa cttgtaagag
    21241 ttcaggatat atttacagaa ctaatggtta cattagacca aaatgcagga caatgggcaa
    21301 aggatatgta caaagtttat gattttgtaa gatatgaact ttcaagagcc aatattagaa
    21361 aagacatcca ggtaatagat aatgtgttac ctgtaataga acaaattaaa gatacatggc
    21421 atgaagctga taaaaaaagt aaagaagaaa gaagtaggta caaataatgg aattaaattt
    21481 agctgaatta gataagttat caaaagagga attactattg atgcttgtag atggcacagt
    21541 aaaatatacc aatatatcca aagaagctct tttaaataac gactatttga aagcacataa
    21601 tgaacttgta agagttcaaa atatatttac agaactaatg actacattag accaaaatgc
    21661 aggacaatgg gcaaaggata tgtataaagt ttatgaattt ataaaatctg aattagcaat
    21721 agctgatgaa aataaagata ttaaaataat tgatgatata ttgccaatag taaaacaaat
    21781 tagagataca tggcatgaag tttacaatca actaaaaata taattagatg gagggataaa
    21841 ggtatgtcaa gtataagtcc tataagagtt acaggtcttt caggaaattt tgatatggaa
    21901 ggcataatcg aagctagtat gattagagac aaggaaaaag ttgataaagc aaaacaagaa
    21961 caacaaatcg ttaaatggaa gcaagaaata tatagaaatg ttatacaaga atcaaaagat
    22021 ctttatgata aatatctaag cataaattct cctaatagta tagtaagtga aaaagcatac
    22081 tcttctacaa gaataaccag ttctgatgaa agtattatag tagcaaaagg ttcagctggt
    22141 gcagaaaaaa taaattatca atttgcagtt tctcaaatgg ctgaaccagc aaaatttact
    22201 attaaattaa attcaagtga acctattgtt cgacagttcc ctccaaatgc cagtggagcg
    22261 agttctttaa ctataggaga tgtaaatata ccaatatctg aacaagatac tacaagtact
    22321 attgtaagta agataaactc cctttgcgca gataatgata taaaggcttc ttatagtgag
    22381 atgacaggtg aattgattat ttcaagaaaa cagactggtt cgtcatcaga cattaattta
    22441 agagtaattg gaaatgacaa tttagctcag caaattgcta atgataatgg tatcacattt
    22501 ataaatgatg ctggtggaaa caaagtggca aatgtatatg gaaagaatct agaagctgat
    22561 gtaactgatg aacatggaag agtaactcat ataagtaaag aacaaaattc atttaatata
    22621 gataatattg actataatgt aaattcaaaa ggaactgcaa agttgacttc tgtcactgat
    22681 actgaagaag ctgttaaaaa tatgcaagca tttgtggatg attataataa actgatggac
    22741 aaggtctatg gtttagttac tactaaaaaa ccaaaagatt atccgcctct tacagatgcc
    22801 caaaaagaag atatgacaac tgaagaaata gaaaaatggg aaaagaaagc taaagaaggt
    22861 atacttagaa atgatgatga gttaagaggt tttgttgaag atattcaatc tgcatttttt
    22921 ggagatggaa aaaatattat tgcattaaga aaactaggta tcaatgaaag tgaaaattac
    22981 aataaaaaag gtcaaatatc atttaatgca gatacttttt caaaggctct tatagatgat
    23041 agtgataagg tatacaaaac actagcaggt tattcttcga attatgatga taagggaatg
    23101 tttgaaaagc taaaagatat tgtatatgaa tattctggaa gttcaacttc taaacttcct
    23161 aaaaaagcag gtatagaaaa aactgcttct gctagtgaaa atgtatattc aaaacaaatt
    23221 gcagagcaag aaagaaatat aagcaggtta gttgaaaaaa tgaatgataa agagaaaaga
    23281 ctttatgcta aatattcagc cttagaatct ttgttgaatc agtattcttc ccaaatgaat
    23341 tatttctcac aagcacaggg taattaatta tggataaatt aaaagaaaaa ttaaatttat
    23401 ataaagatat atctttacaa attataaatt tgattgaaaa ggaagaatat ataaagataa
    23461 gtattaagtt aggtgaaaga caagagatta taaatagtgt aagtgaaatt gatagaaatg
    23521 attttataca gctttataat agaatggaat taattgaaat tgatagcagg ataagagata
    23581 ttttacaagg acaattatta gaagtaaaaa aagaattaca tgagtataag cttactaaac
    23641 aagtgaacac aatgtattat aacttaaata gagaaaaagt aaatattttt aataaaaaag
    23701 tataaagtta tgtaccatct tgtccgatta tataaatgaa gaattaataa aaaagattaa
    23761 aagtagaaat gacaaggatg tcaactatac taaggagggt aaaataatga gagttaatac
    23821 aaatgtaagt gctttgatag caaataacca aatgggaaga aacgtaaatg cacaaagtaa
    23881 gtctatggag aagctatctt ctggtgttag aattaagaga gctgctgacg atgctgctgg
    23941 gcttgctata tctgagaaaa tgagagctca aataaaaggt ttagaccaag caggaagaaa
    24001 cgttcaagat ggtatatctg ttgtacaaac agcagaaggt gcattagaag aaactggtaa
    24061 catactacaa agaatgagaa ctttatcagt acaatcttca aatgaaacta atactgctga
    24121 agaaagacaa aagatagctg atgagttact acaattaaaa gatgaagttg aaagaatatc
    24181 aagctcaatt gagtttaatg gtaagaaatt acttgatgga agttctacag aaataagatt
    24241 acaagttgga gcaaactttg gaacaaatgt tgcaggaaca tctaacaaca acaatgaaat
    24301 aaaagttgct ctagtaaata cttcaagtat aatgagtaaa gcaggtataa caagttctac
    24361 aatagcaagc ttaaatgcag atggaacttc tggaacaaat gcagctaaac aaatggtatc
    24421 tagcttagat gtagctctta aagaattaaa tacatcaaga gcaaaattag gggcacaaca
    24481 aaatagacta gaatcaactc aaaacaactt aaataatact atagaaaatg ttacagcagc
    24541 tgaatcaaga ataagagata cagatgttgc ttcagaaatg gttaacttat ctaaaatgaa
    24601 tatattagtt caagcatcac agtcaatgct tgctcaagct aatcaacaac cacaaggagt
    24661 tttacaatta ttaggataaa ataattttgt atattggata tagaagaaag ggtaaggctt
    24721 tgctttactc ctttcttttt ttacaaatat acttttgaaa ggaaaattta tatgttactt
    24781 agtatagtta tgattgttaa aaatgaagaa aaaatacttg aaaaaacttt aaaatcatta
    24841 accacattaa gaaattctat agaaagtgaa cttataatag tcgatacagg ttctacagat
    24901 gatactataa aaatatctaa gaagtacacg gaaaaagtgt attttcataa ttggaataat
    24961 gatttttcta gtatgagaaa tatatcaata tcctatgcta aaggtgaatg gttacttata
    25021 ttagatgcag atgaaatact aattgattct tcaactattg taaaattttt taaagatggt
    25081 cttgataaaa aatttaattc tgcttcaata caattaaaaa atctttactc atatgataaa
    25141 aaattatatg gatattgttc agtgcttaga ctttttaaaa acgttgattt tagataccat
    25201 ggtaaagtac atgaacaacc aatatacaaa aaccctatat ttaataatgt tgctgatttt
    25261 gaacattatg gatatttgtt tgaagatgaa gaaataagat taaataaggt gaaaagaaat
    25321 gaaaaactat tatttcaaga gttaaaagag aatgataatt ctccatatac aaactatcaa
    25381 ttagggaaaa attttattat attaggaaaa tatcaggagg ctttatacta tcttgagaaa
    25441 tcttatgaat tatattctaa actagaattg gcacctggtt acttgataac aagccttgta
    25501 aaaacatatt tatatttagg aaaacataag aagtgtgaaa gattgtgctt aaagtatatt
    25561 aagaaagaca tgaataatat tgatatatat tattatattg cacaagcaca agtagattta
    25621 ggaaagtatg aaaatagtat agattcgtat aagagatata tttacttgtt agataattat
    25681 gaaataagta cacaagcaaa tagtttattt tcagacactg atactgtagg gcttagagat
    25741 gaggctatta ttacactgat aaagatttat tataagcttg aaaaatatga gtttgtaatt
    25801 tcagagtata ataacattga agatgtggaa aagaaaaaga atgtgtactt tagcttattt
    25861 atgtcactat ataaattgaa tagatttgaa gatataaaaa attattataa agaagtttca
    25921 aattctaaaa ttgaaaaaaa tagtttttat agaaatatag aagaagttat aaataatatt
    25981 aaagaggatg aaaaagagta tgtatataaa atcctttgtg acattgaagg taattatggc
    26041 attttaaatc aaataaggat aaataaatgt gtatctatag ataaatgtaa agaaatactc
    26101 aatgaagaaa aggaaataat ttatgcatat attataaaaa tagcttttga agagaagatt
    26161 gatttactag atatttttta tgaaatggaa tatgtatgga tagagaaata tctaaaatat
    26221 cttttagcat tagaaagaag ttttaattta gtactatata agtacataat tagtcgtcca
    26281 aatacatcag atatggaaaa gataagagta tataaagcta tatctaaagt agttttagaa
    26341 agtataagct taagtgatga aaaatataag gagatttttt atctttatat aatgtattct
    26401 tataagtaca taagatacat atatagcaat ttaagtgatt ttgaattaat aaaatttgtt
    26461 tgtaatgatt tagataagtt cactatagaa tttaagcatc tacttgatat taaaaataaa
    26521 gtaaataatg ctaatgaaaa attagagtat atacatagta tgaggaaatt actaaatgag
    26581 tatccttttt ataataaaat aataaaaata cttataggtg aattagaaga aaatataaaa
    26641 gaaagtgaag aatttaagga tttaaaagat agttttatta ttagtataga aaatatgatt
    26701 gaaactggca aaataaatga tgcgaaatta ttggtagatg actattcaaa aacatttgtg
    26761 gatgatataa agattttaaa tataaaggga attttataca tgtttgaaaa taagcttgat
    26821 aaagctgatt ttatgttaaa aaaggcatta tcattagatg tagaaaatga agatactata
    26881 tataatatag aatacttaaa aagtttaaga taagtcaaaa ataggagaat tgaagaatga
    26941 atataccaat agtggttaat gaaaaatcta aagacataat aaaagattgg caatatacat
    27001 gtacaaatga agatataaaa tttacaagca taataatatt gacatataat caaatagaat
    27061 atactaaatt atgtattgaa agtattagga aatttacccc aaagaataaa tatgaaataa
    27121 taataattga taataactct tctgatggaa cagttgagtg gttaaaggga caatctgata
    27181 taaaatctgt gtataataac aaaaacttag gatttccaaa aggatgcaat caaggtattg
    27241 agttagctac tggtgaaaac atattgttgt taaataatga tgtaatagtt actccaaatt
    27301 ggctctataa tttgaataaa gctttatggt ctcaagataa tataggtgct gtaggaccta
    27361 ttacgaatgc atgttcatat tatcagcaaa ttgatgttga ttataagtca attgaggaca
    27421 tgtttatatt tgcacacaaa ataaataaat ctaatattaa cctatggaaa tatagattga
    27481 agttagttgg attttgcatg ttaataaaaa aaactgttct ggataatgta ggggttttag
    27541 atgaattatt cacacctgga aattttgaag atgatgattt atcttttagg atgatagagt
    27601 caggatataa gttattatta tgccaggata cttttataca ccattttgga agtgtgtctt
    27661 ttaaagaaaa tcgtaataaa tatacagata taatgtatat taatagaaga aaatttgaaa
    27721 ctaagtgggg atttaatcca gaatatagtg gaatgataag aacagatttg atttctaaaa
    27781 tagatgatag tttggaggca aatattaatg ttttagaaat aggatgcggt ataggggcta
    27841 ctcttttaga aataaaaaat atatataaaa atgcatcaat atatggaata gaaattagtg
    27901 agtcagcagg taaacttgca aagtatagtg cagatgtact tatagcaaat atagaaaaag
    27961 taaaattgga ttataaaaaa gatttttttg attatataat attgggagat gtacttgaac
    28021 atttgattga cccatggaag atagtcaatg aattgaaaca atatctaaag aaggatggtt
    28081 atctggtatc tagtatacca aatattatgc atgtttctgt tttaagaaat cttgtgttag
    28141 gtaattttac atatgaagat tcaggaattt tggacaagac tcatttaagg ttttttacat
    28201 taaatgagat aacaaaaatg tttaatgata gtaattacat aattaatagt attacagcta
    28261 ctagtatgcc actttcggaa attgataata gcttcattga tacaatatgt aaggaaagct
    28321 gtaaagaaat gagacaacag tacgaatctt atcaatatat agtaaaagcc tctaaaatcc
    28381 tagatactaa aagatattct agtattagta tgattaattt aaaatacgct ttaatgagaa
    28441 ttgataatga attagatgta gatagtaatt taagttatat atttgataat tataatataa
    28501 ctgaaccatg ttttgttgat gatattgaat atctaattga tacatttgtg ataaataaag
    28561 caactctatt aaatagatta ggagttgagg catttaacag aggtctagga gattttagta
    28621 taaacatgtt tatgacagta ttagagatgg atagagatga tattgactca atatataata
    28681 taacaagtgt attatgtgaa ttagaagaat ttgatactgc ttataattta attaaaaata
    28741 gtagcgaaaa agtacagagt gaaagtgata tacaagagat actttgtttt attgagggga
    28801 agaaatatga ataatgataa gatatgtttt ataacctgtg taaatgatga aaggctttat
    28861 gaagaatgtc ttgtatatat aaatagccta gacattccta aaaactttag tatagaaaca
    28921 gtagctttaa gaggagccga ttctattgcc tctgcttata ataaagctat gagagaaaca
    28981 gattctaagt ataaggtata cttacatcaa gatactttta taattaataa aaatttcata
    29041 catgatattt tagagatatt taaaaaaaat acagatgtcg gaatgattgg tgtagctgga
    29101 gtaaaagata tgcctgtgaa tggaatttgg tgggattctg ataaaaaagc agggaaagta
    29161 tatgatagtc atacaggtaa aatggatatt tatgaattta gtaactttga agaatgtttt
    29221 aatgaagtta tggctataga tggattaatt atgattactc aatatgatgt attttggaga
    29281 gaggataagt ttgatgggtg gcatttttat gatttgtcac agagtatgga gtttagacaa
    29341 aataaataca aagttattgt accaaaacaa aataagcctt ggtgtatgca tgattctgga
    29401 gtagtaaata taaataatgg atatgatgaa tataggataa aatttgtaaa agagtacata
    29461 aatcttgatt tatatagaga aaatttttat gaatttgata agaagaaagc aagtaccata
    29521 cttaagagta ataagcatgt aatggattgt atgaaagagg agcttacaga acaattaaga
    29581 ttaaagaatt acaaggatgt tttaggtatt gtttctaaaa ttgctcattt ttctgttttt
    29641 aatcatactg gtttgtattc ttgtgaagaa tgtgagagag cattgctaga atgtgcaaat
    29701 aatttaccag aaatagaaaa tacgaaatta tttacaaaaa aagatttaaa aagaagaaaa
    29761 gtattacatg ttttaagtga aggatattca acaggaggtc atacaagact agttaaaaat
    29821 tggattgaaa ttgacaaaga ctctgttcat tcagttgtaa ctacatggca atcagataca
    29881 ctgccagact ggttattaaa agcaataaat gatagtggtg gcgaagttat atctttggat
    29941 ttaatttcag atgattattt aaaaagagct gtagctttga ggaaaatagc ttatgactgg
    30001 gctgatatag ttattttata tgttcatatg tgggatacaa tacctgttgt tgcttttgga
    30061 gttgatggga aaatacctat tttacatgtt aatcactatg atagtacttt ttggttaggg
    30121 acaagtattg cagatattgt cattgatttt agcgaagcta gtcaattaat tacattagat
    30181 aaaagaggca tagataaatc tgaaatatta ccaatgccat taaaagaaaa agaagtattt
    30241 tcaaaatctg aagttagaaa acgatataat ttagaggatg atgtgacaat aatattgact
    30301 attgctagtg aaagaaaata caatagtgta aatgatatta attactttaa aattgctaaa
    30361 acattgattg aaaatacaga taatacaatt attattgttg taggagttga tacagagaat
    30421 ctctattgga aaactttaag taacgttaca gataatagag ttatatgttt tggaacaaca
    30481 gcaaatatag acgattttta caagatttcg gatatatata tggagtcttt catggtagga
    30541 agtcatactt caaaactaga tgcaatttta tatgatttaa ttcctgttaa gtttaaaaat
    30601 gaagtttcac caatttttac aaatatgtgg aattttatag ataagtttga ttataagaat
    30661 ataaaagagg ttatagatat gataaaaagg tacaatacta gtgaatttga cagggatagg
    30721 ataaaagaaa aacaatcgga aataaaacat tttgttatag ataaacactg tattgaaata
    30781 aaaaactata tagacaaaat atataatgaa gctaatcatc ataaagttaa gtatgattta
    30841 tataaaaatg atgaaatcga ggactatcag ctttttgtag cattatatgg ctatatggta
    30901 aaaaataaaa acatgtcata ggtggtaaaa tgaacaatat tcatatcaat aaatttgaaa
    30961 aaagctgtga aagaaactgg gattattttg tagaaaataa atctataaat ggtacatttc
    31021 tgcaaactag aaatttcctt aattatcatg aggagggaaa attcactgac cactcattaa
    31081 taatatgtaa aggtgaagaa atactagcag tcgtacctgc atgtgaaact tatgaagatg
    31141 gtgaaagaat atttttttct catttaggga gtacttttgg tggtattata ataagaagtg
    31201 gttttaatga tattaggcat gtaaatgcca ttacaaataa gttagaaata tatttacggg
    31261 aacaaaattt cgataaagta tatttaaaaa atacatcaag aatattttgt aaagaggata
    31321 cttcattact agaatatttt ttatttaaga ataattacat gttttatgat gaattaagta
    31381 tgtttttaga attaagtaag tataaagaag atatattagc caattttaaa tacagtaaaa
    31441 gaagagattt taaatattct ttgaagaata atcttacctt taaaagactg tatagtgatg
    31501 aagatatagt ttgttttttt aatttacttt ctaattgttt agatagtaaa ggagctaaag
    31561 taatacattc agtagaagaa cttttggagt ttaaaaataa tagattaaaa gatattgtag
    31621 aattttatgc agtatatatt gatgacatta tgatttgtgg gagcatggta tttaactttc
    31681 aagaaagagt ttatcatact caatatctag catcaaattc gacatataat aaatattatc
    31741 caatgatatt tttatactat aatctaataa aagatgcttt agagagaaat tttaagtatc
    31801 tttcttttgg aattagcact ctaaatagag gcaaatactt agacgagggt ttagctacat
    31861 ttaaagaagg ttttggttca agtgcaattt gtaacagaac atactataaa aatataaata
    31921 agtgagaatc atgttttata gagtttttag aatatagtaa atatctagta ctctaacatt
    31981 acataaaaat aattagttta taaagaaggt ttgtatatga aaagattaat gattttaggc
    32041 tcaattaagt attttgagaa tattgttata tcagctaaaa aagagggaat atatacgatt
    32101 gtttgtgata atagaattga tactcctgcg aaaaagattt gtgatgaagc aatagatgtt
    32161 gatgtatttg attttgataa aataaaaagt atagctatag ataaaaagat agatggaatt
    32221 ttaactggat ttacagattc tttaatgaaa ccatatgttt atattgcaaa tgaactaaat
    32281 ttaccatgtg tgatttcttg caatcaactt gaatctgtaa ctaacaaggc tattatgaaa
    32341 aaatatttta aaaataatgc aatacctaca actgattact gtattattga aagtctaaaa
    32401 gatttagaaa aaatacaagg attaaatttt ccacttgtaa taaaacctgt tgatggttat
    32461 ggttcaagag gtgtatattt tgtatcaaat atagaagaat taatagaaaa atttgaatat
    32521 tctaaggaag cctcacaaga tggacaagta ataattgagg aattttatga aagtgaggaa
    32581 atacaaggac tagcttgggt tcataatgga gagtcacatg tattttatat tggagataga
    32641 gagcttgtaa acatacatac aggaagagct ggaaaaccag atagattact ttatccatca
    32701 aagtattgtt ttcaatatga ggaggaaata aaatctatat atcaaaatat aacacaggct
    32761 tttgatataa aaaatggacc tctttatgta caaatgttag tgggagcata tggaataaag
    32821 gtatctgaag taatgccaag attacctgga ggttgtgact atatggctat ttctcaaata
    32881 acagatttag acataggaag tttatttgca aactttagtg tgaataatga agtaaatttt
    32941 gatgaaataa agaaatataa tatgcatcta tcaaaatgtg tatatgcatt accaatatac
    33001 ataagacccg ggacaataaa aaagataaat aatatagata aaatagaaaa cttagattat
    33061 gtcactcaat ttctattact agtaaaagaa ggagatacaa tagaattata tgaagatgag
    33121 agacaggatt gtggaagagt ttatggaata gcaaataata tatttgatgc aaatataaaa
    33181 aagaaatgta ttcatgaaat gatagaaata cttgatgaaa ataatgaaaa tatgatagaa
    33241 aatttttaaa taagggagta tgatagatat gaagctaata actcatgaac aaattatgtc
    33301 attaaacatt tctcagaaac aaggatatga gtggataaaa gaatctttct taacaaaaaa
    33361 agattgtcaa ttaccaccaa aaataagcat ggtagaagaa ggacatgtat tttacaatgt
    33421 aatgccatcc ctaaatcata atcatatgat tggtggaata aaaatggtta caagattgcc
    33481 agggagaaat ccaagtttaa actcagagat atttctatac aatatggaag atgctaaatt
    33541 aaaggctatt ttggatggta attatattac agcttttagg actgctgctg ttgctgcctt
    33601 ggctatcgat acatttgcta aaaaagattt taatactatt gctattatgg gtttaggtgt
    33661 aactgcttct gctataatga atatgctttc atatactctt aaagataaaa atataaatat
    33721 aaagttactt aaatataaag accaagcaga gttgtttgta aaaaagtatg aaaaaaatga
    33781 acaatttagt tttgaaatat gtgatacaca tgaagaactt attgtagatt cagatgtagt
    33841 tatttctact gtgacatata cagatgaata tttatcagaa tttaaatggt ttaaaaaagg
    33901 tgctttatta ttacctgtac atgttatggg atttggaaat gttgattatc tatttgataa
    33961 agtatattta gatgattata atcatttgaa acatctagaa aatatagata gatataaata
    34021 ttcttgtgaa ttttatgatg ttttaagtaa acaagctaaa ggaagagaaa atgatgatga
    34081 gagaataata tcttacaata taggtttgtc aatacatgat atattatttg caaataaaat
    34141 ttacgaattg tgtgaaacac taagctgtga agaaatagaa ttaaaagaac caaaagaaaa
    34201 atattggata tagtttattt cattcatatt tacaatagtt tattgtaaat atgaatatga
    34261 agtaatatat tgttagaaaa ttagcatgaa taggatagat aaatttatgg ataaatataa
    34321 tttaattagg ttcgtatcta ttggaaacga atatatagga aatttagttg cattagaatc
    34381 aaataaagta ataccttttg atataaagag agtttattac atatatgatg taccaaacaa
    34441 tgtaaagaga ggatttcatg cacacaaaaa cttggaacaa gtactagttt gcctaaatgg
    34501 aagtgtgaag ataaaatgtt atgatggtgt aaaagagact atatttaatt tacataaaaa
    34561 tgatgttgga ttatatatag gaacgggagt gtggcatgag atgtttgatt ttgatgaaaa
    34621 aactgtttta atttctatag catctgaaca ttataatgaa gaagattata ttagagacta
    34681 taaagaattt ttaaagtatt taaataatgt gtagttatta tacaattagt gatgtatttt
    34741 cttaattaaa taaatttaag atagccacat agagaataga tagattagga tgtgaattta
    34801 ttgttggtta aatttaataa tttattaaaa cagttccaaa ctcataaaga agaatatgaa
    34861 cagaagatta aggatgtaat ggaaagtgga tattatatcc ttggaaatga agtaaagcat
    34921 tttgaagaag aatttgctaa ctatgtaggt agcaaatatt gtgttggttt agccagtggt
    34981 ttagatgcac tgataattgc ttttagagca ttaggaataa gcaaaggtga tgaagtaatc
    35041 gtgcaatcaa atacatatat tgctagtgtt atgggaatca gtataaatgg agcaacacca
    35101 gtatttgtag aaccaaatga atattataat atagattcat ctaagataga agaaaagata
    35161 aatagcaaaa caaaagctat attagtagtg catttatatg gtcaagcaag taatatgaaa
    35221 gatatacaag aattatgtga taagtataac ttgtatttaa ttgaagattg tgctcaatct
    35281 catggagcta aatatgatgg aaaaatgaca ggaacatttg gtgatatagg ttgttttagt
    35341 ttttatccaa gtaaaaattt gggtgcattt ggagatgcag gagctatagt aactagtaat
    35401 gaggaaatag ctgataaagt gaaaattctt agaaactatg gctcagaaaa gcgatattat
    35461 aataaatttg tcggatataa ttcaagattg gacgaaattc aggcaggttt attaagagta
    35521 aaacttaaat atctaaatga aattgaaatt gaaaaatcaa aaatcgtaga tagatatctt
    35581 aatgaaatta ataatcccaa agtcatactt ccaaagatag aaaataattg tactcatgta
    35641 tggcatttat ttgttttaca agttgaaaaa cgagatacat ttatggaata cttaaagaaa
    35701 agtggtatag agtctataat acattatccg ataccaccac atctatctga agcatatgct
    35761 tatttgggat ataaaaaggg gagttttaat atagctgaga actattcaga taaagttgtt
    35821 agtatacctt tatttattgg tatggaagat gaagaagtta gttatataat taaaattata
    35881 aatgaatatt aaactactca taataatatc aaaaataaat tttttatata tcatttattt
    35941 aaatttcgtt aattgacatt tttaaatatt gatatattgt acaaataaaa ttgaaatata
    36001 tggaaaaata tagaattaag atgagatttg tcttatattt ttataaatta aaaatatttt
    36061 caaagagttt attataaaat tgtaaactat agtgtttata atctttgtaa ttattggtaa
    36121 ttaaatttaa aaaataaaat atttaattat acacaaaaaa gatatttaaa aaatttgtta
    36181 tttattgtat acttaagtta aaactaaata ggcaaatcta gagaaatcta gtgacgcaaa
    36241 gctataggga ctaaggttta tatacataaa ctatgtcagc cagttgccaa aaagagtcct
    36301 aggtgtattg tatacctaag aaaagtctat aatgactgcc tttttggcag tcattttgtt
    36361 atggaaaaat cactttattt cagtagaaaa tacacataat aacatatttt accaattata
    36421 acataaaata aagaaaaatt atctcaaaaa gttactattt tacaaaaaag agcaactttt
    36481 cgaagaaata tttaaataca tattaaaatt tttttatatt ttcatgggac ttcattaaaa
    36541 aaatattagt tttcttacta aattgataca ttattgtatt aatgtaatgg aaatgcgatt
    36601 aatttaaata aataaagaag tcattttttg taatatagca acttcatttt ttttattaat
    36661 aaacaaaata gataaaatat attttgagga ggggtgagtg tgaatacata tgacattata
    36721 aaaatgggat tagatgcaac taatctaaga agtcagacaa tagcaaataa tatagcaaat
    36781 ataaatactg aaggatataa aagacattat ataacttttg aagaaacact aaatgatgct
    36841 atgcctaaaa tagaagaaaa aacagacaat tctaaaggtt taagagtaga tggtaataat
    36901 gtagacatag aagaagaaaa agtaaatcaa gcaatggcaa cattacaata taatgctttg
    36961 ataagttttg caaatggaaa aatagcaatg accaaatcaa taataagtgg gaggtaatta
    37021 gaagatgagt gtgttcagtg gaatgagaat atctgctagt ggattaacag cagaaagttt
    37081 gaaaatggat atcatatcat ccaatgtagc taatataaat gctacaagag gtccaaatgg
    37141 agaagcatat aggagaaaag ttgtttcatt tgaagaaaac tatgataata aattaggtat
    37201 gctaggagta aaagttacat ctgttgaaga tgataaatca cctcttaaag aagtatatga
    37261 cccatctcat ccagatgcaa agccaaatgg atatgtagaa tatccaaatg taaatatatt
    37321 ggtagaaatg acagatttaa taacagcttc acgagcatat gattctaacg tagatacatt
    37381 gaatgctcag aagtctatga tatcaaaagc tttggaaata ggaaagtagg gataaattat
    37441 gccaattaca caaattaaca atttaatgca aggtgcaaag ttagataatt tgattggaga
    37501 agcaaagcca ttaactctta ataataaaga agaaaaaaag aattttgaag atgtaataat
    37561 agatactata gataaagtta attttcaaca agtaacagca gatgatatga aagaaaaatt
    37621 tataaaaggc gaagatgttt ctatgcatga agttatgtta ataggtcaag aagcacaact
    37681 atctatgcaa tatttaatag aagttagaaa taagattcat gatgcatatc aagaaatgaa
    37741 taaggtgcaa atttagcctt ttgaacagga gtaataatca atgataacca gttttaaaaa
    37801 taagattaag gagcaagttg ctaaatctag gacaaagata agttctttaa aaaagggaac
    37861 taaaatagca ttaggtatag gggttattgc tatatgttta gcgctagtat ttacagcaat
    37921 atctgcgagc aaaaataagt atgcagtctt attttcagaa ctagatgctc aagatgctgc
    37981 agatatatca gcagagctag agtctaaaaa gatagatact aaggtaaaag gaagtacgat
    38041 ttatgtacct agaacagaag ttgataagtt aaggctggag ttagcgccaa gtcttacagg
    38101 tggttctaaa ggatttgcac taatggatga tagttcatca atagggctta ctgatgaaga
    38161 atttcagatt aagaaacaaa gaatgataca aggtgaaata gaaaaaacaa taaagagttt
    38221 tccacaagtg gaagacacta gagtacatat aacatttgga gagtcatcag tatttgagaa
    38281 ggaggctgtt ccagggagtg cagcagttta tttgatgcta aaaccaggga cgactttaga
    38341 aaaaaaccaa ataaagtctg ttatggcact tatatcagga agcgttacaa atataccaga
    38401 gaaaaatgtt caggttattg ataacaaaat gaatttatta tctgaaggta ttttggagga
    38461 tgaaaatgtt gatgaaaata atcaaccaat aaatagtggc attagtgttg ataaaaataa
    38521 ggcatctgaa caagcattga ataaacaact agaaaagtct attttagaaa tgctagaacc
    38581 gatatttggt aagggaaagg tgaaagctac agtaaatgct gatttaagtt ttgatacagc
    38641 tgaaaaaact gagataaaaa ttgaccctga taaagttgca ataaaggaga caaggtcgaa
    38701 aaattcatct aaatctgctg caaataatgt tcaaggtgta gatgctaaca tgaataacca
    38761 aggaaataac aatggtacta atacagaaga tagtttagat gagagttttg agtatgaaac
    38821 aggtaagatt gaaactcaca ctatagttgc gcctggagaa cttaatagat tgacagcttc
    38881 tgttgcaata gatggaaaaa tagctaaagg tgttcaagct gatgtagagg atattgttaa
    38941 taatgctata ggtatggatg gagcgagggg agatactctt agcgttgttt caatggtatt
    39001 tgacccagaa ggtaagaaag aggctaaaca agagctggaa gagattaaaa aagaaggatt
    39061 taaaaagaac ataataaaag cagttattgg agtagtagca gtaatagcag ttggagctat
    39121 tggatactta atatataaga aaagaagtga acgagaagat atggattatg aagatgaaga
    39181 ttatatttct aaatctgatt ctgttgatag gaaggataat cctctattag gagatgaccc
    39241 agaactgaca ttagaggaag ctgttaaaat gtatgcagaa gaaaagccag accaagtaac
    39301 agagataata aagacttggt taaatgagta agggggatag aaagtgtcca cggaaattac
    39361 aaatgttaat gcgtttgact taagtgatat aaatgaaagt gataagaatg agaaggtaga
    39421 aggtgagggt ttaaaaaaag ctgctgtatt attaatgaca ttaggcccaa atgtgtctag
    39481 tgatataata aaaagcttgc ctgataaaca agttcaaaaa ataggtttgg aaattgcaaa
    39541 tatttcttca atagcttcaa aagaaagaag agaaatctta aaagagtttg tagaaataaa
    39601 tagggcaaaa gattatgtta tagaaggtgg gcttgaatat gcaagagagt tattaagtaa
    39661 tgctttagga aatgttaaag caaacaaatt acttgaaggt atatcaataa atacaagtac
    39721 aaagcctttt aaacatatta taaaactaga tgtaaagaag atattagaaa tacttaggaa
    39781 tgaaagtgca caaactatag ccgttttact tgcacatatg gaaccagaaa atggagcaga
    39841 agttttatca tacttagatt ttgatttaca aaatgaagta gctatgagaa taagctcaat
    39901 gggttcaata tctccagaag taataaaggt aattgaaagt tcattagaag ataaattaca
    39961 ttcaataagt ggtgatgatt ttaatgatta tggaggggtg tctaccttag ttcaaatatt
    40021 gattaattct gatagaaaaa cagaaaagaa tattttggga actattgaag aacaaaaccc
    40081 ggatttagca gctcaaatta aatctcatat atttgtcttt gaagatattg tcaagttaga
    40141 tgatataagc atacaaaaag tgttaaaaga agtgactatg aaagatttag tatatgcctt
    40201 aaaaggtgta gatgatgaga tttcagatgc tatatataga aatcaatctt ctagagcagc
    40261 agatgcactt aaagaagaaa tggaaatggt tggtgttata aaggttacac aagttgaggc
    40321 ttctcaacaa aagatagcta atatcgtaag aaaacttgaa agagaaggtg ccataactat
    40381 tgtaaggaat tttggtggtg actttgttga ataataagat tattaaaagt aaaaaagcat
    40441 tatataaagg agtgctagat ttaaccataa tagataaagt tagagtggga gaatcaaatg
    40501 taaataaaga aaatgattgt agatttaggg atgaggtaat aaaagaagct atagaatctg
    40561 ctgagataag aaagaatgag atattagaag aagcaaaaat gaatgcacaa aatatagaaa
    40621 agcaagcata tgaaaaaggg tatagtcaag gtcaaaaaaa tggatatgaa gatggatata
    40681 aagagtcata tgatgaatat acccaaaaag ctaaagatga agcagatttt ataaaaaatc
    40741 aggcagactt aatactatta caagctaatg agaagatgac tgagtacata aaagaaaaaa
    40801 ataaagagat tgtaagactt gctattaata tggctagttc tgttctaaaa aagcatttcg
    40861 aagatgaaga atctatgagt gatttgttaa agcaaattat tcaagattat gaaggaagta
    40921 gttcatttat agtaagatgt aattctttct ataaagataa tatagagaaa gagtttgaat
    40981 tattcaaaga ggaaacatca ctaaaatcaa gtgtatttgt tattgcagat gatagtatag
    41041 ataaaggcaa tgctattatc caaaaggaaa atggaagaat aatagttggt attgattgtg
    41101 ctatggaaaa actaaaagaa gaattgcttg gtgaataaag tatgtataaa actgatatat
    41161 ctatagattt tgacaaaata aataagaaaa tagaaaattt agaactcact atatcagaag
    41221 gtagagtaaa gaagataata ggacttactg tagaagttga aggaataaaa gcttttgttg
    41281 gggagttatg cgttatatac aaccaagtta ataaaccagt gaattgtgaa gtagtaggtt
    41341 ttaaagataa agaagtcata ttaatggcgt tgggagaatt aacattgata gcacctggtt
    41401 gtaaagttat ttctaagggg atacctttaa gtgttatgtg tagtgataat ttactaggta
    41461 aagtacttga tggtcttgga aatcctatag acaactcaga tgctgtttta ggagatagat
    41521 acaacctgaa caatgaacct cctgacccaa tgaagagaaa aaagatacga aatataatgg
    41581 aaacaggtgt aagagcaata gatgcattta ctacttgtgg tgaaggacag agaatcggca
    41641 tatttgcagg aagtggagta ggtaagagta cgactctagg tatgattgct aggaatgcaa
    41701 aagcagatgt aaatgtaatt gctcttattg gagaaagagg aagagaagta ctagatttta
    41761 ttgataaaga tttaggtgaa gagggaatga aaaaatctgt tgttgtgtgt gcaacatcag
    41821 ataaagcccc tctagttagg ttaaaaggtg ctcttactgc tactgcaata gcagaatatt
    41881 ttagagacca aggcaaaaaa gtaatactta tgatggattc agtaactaga tttgctatgg
    41941 cacaaagaga agttggtgta gcaataggag agccaccagc tcaaaaagga tatacaccat
    42001 ctgtatttgc aatgttgcca aaacttatgg agagaacagg gacatcagat aaaggttcta
    42061 taactgcatt ttatacagta ttagttgatg gagatgactt taatgagcca atagcagata
    42121 caacaagagg gatacttgat ggtcatatag ttttatctag agacttggca aataagaatc
    42181 actatccttc tatagatgta ttaaacagtt taagtaggct tatgaatgaa attgcttcaa
    42241 aagaagacat aaaaatagcg tcttttgcaa gagacatgct tgctgagtat agagaagcag
    42301 aagatttgat aaatataggt gcatatgctt caggtacaaa caaaaaaata gatgaagcaa
    42361 tctattatca tgagcatatt attaattttt taaaacaagg aataaatgaa aagagttctt
    42421 ttaatgaaac tataagtagt ttaagaagaa tctttgaata aacaatttaa aaaaatattt
    42481 gaataggttg tgatggaatt ggataaaaat tttaagttta gattacagaa agttttagac
    42541 ttaaaaataa aagatgaaga agagataaaa atggaatttg ctaagattca acaaaaaaaa
    42601 atagatatag aaactaattt agaaaactta gaaagtaatt acagcaaata ttctataagt
    42661 aaaaataatg ataatgttca aaatcaaaaa ataactatta actatttgct agctttaaac
    42721 aactctataa tggatttatc agaagaactg gataagtcga caaatgaact tgaaaaagct
    42781 agaaaacagc ttataagcaa acagatagag agaaagtcat tagaaaaatt aaaagaaaaa
    42841 aaatatggac agtattataa agaagaacag ttaaaagaac aaagcactaa tgatgagttt
    42901 gcaagcatga gttatttgag aaatagacaa gttctataaa ataataggaa gtgaggatat
    42961 tattgtatga agatacaagc agattcttat aatattatta aagatattgg gaatagaaaa
    43021 aactcatcta agaataaaaa tataaaaaat aataaatttg aagataatct atataagaca
    43081 acagaccata aaaatgttaa agatagaaga gaaacaagta agcaaaatgt tagttcagat
    43141 agaccgggaa atagtgataa tgagtgtcat ttagatgaag ataaaagtaa tcacttagaa
    43201 gatgaaaata catatgaaaa agattgtagt aagaataatg aagctttaca gcaattactg
    43261 aatcttttaa aagagaatta taaaaaagat aaagatataa acactatatt gaataatata
    43321 aaaaaactaa gtatatcaga tgaattaaaa caagaactta agcttaataa aaatatattg
    43381 aataaaattg caaatcaaaa tttagagtta aatggagcta atacaaataa ccctaatgat
    43441 atagaaaatt tagacataat gaagttaaga gaacttttag aaaataatgc tagtgaagat
    43501 attcaagtaa ttagtaaaac tacagaaaat gatactaaaa gcatagactt atacagtttt
    43561 gatagtaata gaatggatac tcttaactca aataaacaga aagatgatag ttctgatatt
    43621 ttggaaaaac tagcagggtt aaatggaaat aagagtggaa attttggaca agtaataaat
    43681 aaaagcgttg atatgaataa aattaaaaat gataatgtta atttaaaaca gatagaatct
    43741 aatgtaatgg atgattctat aaaagctatt aagcatatga aaacaaatga tatacaagaa
    43801 ttgacaatta aattaagacc aaaagaatta ggagatatga acatacaatt attaaaagat
    43861 ggtgaaagta tgagagctgt tgtgactgtt ttcaataaag atgtctttga ctctataaat
    43921 aaaaacatag cagatttaaa gcaacatctt gaacttacaa atgtaaatat aaaagatgta
    43981 tcagtgcaaa tgcatagcga taatacaaat acatctgata cctttgataa agcatttgaa
    44041 caacagaata gacaaaataa ccaagaaaac atgagtaatc aaaatacaaa tgataagcgt
    44101 aacaatgtag tcatagaaga tgagattaaa gaaaatatta ttgatgatga tagagtagat
    44161 ttactagctt agtaaggggg aagtattgca tgtacggaat agcaacggct ttggcaggaa
    44221 ctcaggtaaa ctataggtca aataacttaa gccaacttga aagaaatatt aatgatattg
    44281 ccaacaaaca agttagaagt aaaggaaatc agacagtaac agacaatggg actccaatta
    44341 taggacaagg tgatgatgct gataaagact tgtttatgaa gattcttgta gcacagatgg
    44401 gtaatcaaga cccaatgaat ccacaagacc caacggagta tgtatcacaa ttagcacagt
    44461 ttgcaacttt agaaaaaatg tcagctatga atgataagct agatatactt ttagccttaa
    44521 gtaactctac tctaataaac tctgctttga gtatggcaac atcattaatt ggtaaagaag
    44581 tagaagtatc tggggaagaa gatgaagatg aaaacattgt aggagtagta aagtccacat
    44641 acataaaaga tggggaagta cacttagaat tagaagtaga tggaagtgac aaaactgtag
    44701 atgttaaata tgaaaaatta cttaaaatag gagaggtaga ggcaaattca ggagaagaaa
    44761 atgactcttc agaacaagaa tctccagaag aagtataata ttaaatggga aaagaggtaa
    44821 atttatgata aaagcaatgt attcaggtgt aagtggaatg aaagcaaatc aaacaaaact
    44881 agatgtaatc ggtaacaatg tagccaacgc tggaactact tcttttaaga aaagttcagc
    44941 tagaataaca gattcatttt atcaaactgt actatatgca agtgctccaa cagcggcatt
    45001 agggggaaca aacttaggac aagtaggtgt aggtagtaag atatcaagta taaacaaaga
    45061 tatgacacaa ggaaatgtac aaccaactaa tagaccatct gatttaatga tagatggaga
    45121 tggatatctt ccagtagtaa gacaaggaac agttatgtat acgagagatg gttcttttaa
    45181 tttagataca ggatttaaag cagctgatgg tgctttgaag aatattaaag gtggaagact
    45241 tgtaaatggt gatggatata tgttacaagg tatgatttat gatggggaat ataaagctga
    45301 tactggagaa tttgttaaaa agggtgatgc taaaggaaaa gagcctattg taataccact
    45361 tcaaagtata agtcctaagg atggaacagt tcaaaatgta ctagagtata atatatcaaa
    45421 ggatggaaca gtagaatttt tattgagtga tggtcaaaga actcaatttg tctatgatat
    45481 acctgatggt gctaaggtag gagatacacc tgctggaata gataaattaa aaggtacaat
    45541 acaaaaagtg caaacatatg cattccaaaa tccagcagga ctagatgcag aaggaggaaa
    45601 cttgttcaag ccatcagcaa actcaggaga cccacaaata gcaggagcta caggcacaat
    45661 aatacaagga gctatagaag cttccaatgt agatatagca gaagaattta cagaaatgat
    45721 aatagcaagt aggtctttcc aagcaaacag taaaataata tcgacatcag acgaaatact
    45781 tcaagaaata ataaatctta agagatagta ggtacatatt atgataagag taacggattt
    45841 aaacggaaga aaatacatat taaattcaga tcttatagtg agaattgact ccgtgccaga
    45901 aagcaggatt ctccttacaa caggagaaaa aaatcttgta aaagagtcag tagatgagat
    45961 agtagataaa gtaataaagt ataaaagaaa aataaatgta ggttatatta ggagtgaaaa
    46021 ataatgaaaa aaacagattc actaacattc attggactaa tattatctac agtattagtt
    46081 ttatttggag cagtaaaagg aagtagttca ggattgaaaa gttttttcga ttttgcatct
    46141 atattaatca cagtatttgg gtcatttgga gctttgatga ttacatttac tattgacgat
    46201 ataaaactta taaaagatgc tctacaatac tcattcaaga caatgaatat atcgaaatta
    46261 gacttattaa atcaatttaa aacactttct aaaaaagcaa gaagagaagg acttttatct
    46321 atagaaagtg atgtaatgaa aatacaagac ccatttatga aaaaaggatt agagttatgt
    46381 attgatggtc ttgaaataaa tgaaataagg tctatactag agctcgaaat agattctgtt
    46441 gaagaaacca ataacagata ttctaaacta tttaaaactt gggggacttt cgcacctgca
    46501 tttggtatgt tgggaactct aataggttta atacaaatgt tatccgacct tacatctcca
    46561 gatttaatag catctggtat gggaaaagca ttaattacga cattttatgg gtctttactt
    46621 gccaatatcg ctttgaaccc aattgcatat aatatagatg agaagactga aaaagaaatt
    46681 tatgtaaagg aaatgatgct ggaggggata ataagcatac aatctggaga gagcagcata
    46741 gtagttgagg aacgtttagc tacatacctt tcaaataatg agaagttaga aattatgaaa
    46801 tccaataaaa atacagaaag agcaatgagt aatggcgcgt aaaaaaaata agaaaaagga
    46861 tgagataaat ccagatgcat ggttggctac ttatgcagat acgataacac tgattcttac
    46921 attttttgtg ttattgtatg ctacatcagt tgtagatatg gaaaaattta aaaatatagc
    46981 agatgcgtta aaaggtcagt tttctgggac aagtatgttt agtacaggtt caagtacaag
    47041 tgagaaatct ccaatagaga gtgttttagt ggataaaaat gataagtcaa atttagaaca
    47101 ggatttaaaa gataaagtta ataattctaa cttacaaaat agtgtaacag tcaaagatga
    47161 tagtagaggg attttactag agctagatga ttcaatttta tttgactctg ggatttctga
    47221 attaaaagaa gatagtaaag ccactcttaa taaagtatac gatatgataa agatgatgaa
    47281 aaataagata gttatagaag gccatactga taatgtacct gtaaaatcaa gtacgcatga
    47341 atccaattgg gatttatctt ctagtagagc agtaagtgtt gtaagatact ttgtagaaga
    47401 aaagggcatg gaccctaaac tattttcggc aacaggatgt ggagagtacc aacctttggt
    47461 atcaaatgaa acagcaaagg gaagagctga gaatagaaga gttaatatac ttataactat
    47521 tgactaggag gaagaggttt gttcaaaaat aaaaaaatta ttataattat tttgatactg
    47581 attattttct cagcaggagc aggttttttt atattaggag aaggtggaaa taaacaaatt
    47641 gacaagattg caggtttgtt tattccaaca gggaaaggca aagatgaagt aaagaccgaa
    47701 aatcttgact tagaagagat ggtattgaag ctagctgatg aaggtgtaag atatttaaaa
    47761 gtatcaataa ctgtatctta tgattcttca tataaagata tagaaaaaaa tacgccttta
    47821 attagggata atattataaa ttgttttatg gcaaaaaggg cagatgattt tactgctgat
    47881 aatttaaaga acataaaaga agaaattaaa aatacattaa atatacaact aggtgaaaat
    47941 gtaattcaaa atatatattt cacaaatata gtagtgcaat aaaaggatgg taagacatga
    48001 tactttattt actaaaaata ttaatatgta tcccaataat tttaatattg atagtcttat
    48061 ctttaaaaat tagccaagga actttattaa aaaaatataa tgataaatat ataaaaatac
    48121 tagatattgt aaatataagt aaaaacaata gcataataat tttaaaaata ggtgaagaag
    48181 gatgcattat ggcatcttct tcttctagca tgagtaaaat aaaagatttg accaaagaag
    48241 aaatattaag aatagaaaac gacattaaag aaagaaattt taaaattcaa gattttaaaa
    48301 tggaaagaat taaaaagaaa tatgatttca gtagatatat tggaaaattt acaaaaaagg
    48361 aagataagta aatggaacta ttatcaaaat tacctttggc tgatgtacca tatacaagtt
    48421 caatgcaatt gtttttattt ctaactgcat taatgttttt accatttgta atgttcatga
    48481 tgacaagctt tgtcagaata gttataagtt tatcattttt gaaatcagca ttaggagcac
    48541 agcaagcaat tccaagtcaa attttggtag ggcttgcaat agtattgaca atatttataa
    48601 tgagaccagt attaaatgag ataaacgaaa aggcattaca accatatatg aaagaagaag
    48661 ttactatgga agaagctatg aaggaagcag aaggacctat taaagaattt ttattaaagc
    48721 aaaccagaca gacagattta gatttatttg tagagcaagc tggtttaaaa gaaaagaaat
    48781 taactcgtga aaatatacca ttatctgttg tagttccagc atttgctata agtgaactaa
    48841 aaactgcttt tcaaataggt tttttaatat atataccatt tttgataata gaccttgttg
    48901 tggcaagtgt tttgatgtct atgggtatgt ttatgttacc tccagttatg atatcattac
    48961 catttaaatt attattattt gtaatggtgg atggatggaa cttgatagta aaaacattga
    49021 tattgggatt tggataggag aaaaatagta tgagtgaatt tatgataatg agtgttctta
    49081 aaaatggcat gtttacagga gctatgattg cagctccagt gctaattgtt tctcttgtag
    49141 tggggctttt aataagtgta tttcaagcca caactcaaat ccaagagcaa actttgactt
    49201 ttgtaccaaa actaatagca attcttttag tagtagctat tggtggaagc tggatgttac
    49261 atactcttat tagctttact tcggagatat tcaatatgat gtctctcata actaaataag
    49321 taggatatat atgatttttg tatttattag aatagtagca ttctttggaa cattaaggat
    49381 actatttcca gctggtacac ctgctttatt taagtcgctc tttgcaatca ttatatcaat
    49441 cttgatttca agtactatgc aaattgaata tgcaacaaat atagacaaca ttgtattgtt
    49501 taccttatat ggtataaatg agaccataac tgggattatg cttggatata taaccaatct
    49561 atgtttttat agtatcagaa tggctggttc tatgatggac caacagatgg gattatcaat
    49621 gattaatatg tttgacccaa attcaatgac tcagacaact ttaatcaata atcttatgaa
    49681 ctggacagca cttatgatat tttttagcat ggatggtcat catgttttaa ttagaggcat
    49741 aaggtatagt tttgagttaa ttccaatagg gaaatcattc atagataata atatagatta
    49801 tataataaac atatttgtgc agtgcttttt aactggattc aaaatagcaa tacctattgt
    49861 actttgtctg cttatggcag attttatatt agggcttata tcaagaagtg tacctcaact
    49921 aaatgtaatg ataattggta tgccattaaa aatactggtt ggtattgcat tatttatcat
    49981 atcaatacct ttaattgtca atcaaataag tcatttatta agtcaaatac caaagatgta
    50041 tgagggaact tttgcactag ctcctatgtt ttttatgggt tcaacagata aaacagaaga
    50101 agctactcca aagaaaaagg gagaacaaag aaaaaaaggt aatatagcaa agagtaaaga
    50161 attacccatt gcaatgactc tacttgcatt cactttatta gtacctacat tattttcata
    50221 tgtagtgaat acacttaaat cttctcttaa ttattttttg agtctagatt tttatatgaa
    50281 cataaattat tcaagtatag agaaattagt tatagcagga ttaatggatt tttttaagat
    50341 atttttacca atagctattc cattcttagt tttaggtata gtcgcaaacc tatttcaagt
    50401 aggaatactg tttactggtg aaactttaaa acccaattta tcaaaattaa atccaattag
    50461 tggattcaaa aacatgtttt ctatgagaag tttgtcaacc ttaataaaag atacagcgat
    50521 tatatctatt ttggcttaca taggatatac attcttccaa gataattatt tagatatatt
    50581 aaagttaggt aacatatacc tgccaacttt aatgtacaca gttaaagatt tagtatattc
    50641 aatattaagt aagatttgtg tagctatgat agttatagca gttgcagatt atgtttatca
    50701 aagatacagt cataaaaagc aacttagaat gacaaaacaa gaagttaaag atgaatataa
    50761 aaactcagaa ggagacccag aaataaaagc taagataaaa caaaaacaaa gacaaatttc
    50821 gtctcaaaga accatgcaag cagtaccaag tgctactgta atagtaacca atcccaccca
    50881 cttatctata gcagtgagat atgaaaaagg gaaagaccaa gctccagtag tggtggcaaa
    50941 aggtgcagat tatttagctt ttaaaataag ggaaattgca aagggaaatg acatacctat
    51001 aatagaaaat aaacctattg ctaggttgtt atataagcaa gtagaaatag accaagaaat
    51061 tccagaggac atgtatcaag cttttgcaga gatattagta gcagtatata aaatcaaaaa
    51121 tagatacaaa gtccccaaaa ggtaggataa gtaatgaata agtttaattt aaaggaaaat
    51181 atggacgtaa tagtggcatt tggtgttgta gggattgttc ttatgatgat agtgccgtta
    51241 cctacattta tattagatat tttactggca attaacataa gtttatctgt gctaatttta
    51301 ctaatgacac tatttacaac aaatgtactt gatttatcta tatttccaac agtgttactt
    51361 gtgacaacac tatttagatt gggattaaat ctttcatcaa ctagattgat tttaacacag
    51421 ggatatgcag gtgaagttat agaggcattt ggaagttttg ttgtaggtgg aaattacgta
    51481 gtaggaataa ttatattctt aattatatta attgttcaat ttgttgttat aaccaatggt
    51541 tctggaagag tatctgaagt aacagctaga tttacgttag atgccatgcc aggtaagcag
    51601 atgagtatag atgcagattt aaatgcagga gttatagatg acaaaactgc tagaaaaaga
    51661 agaaaagagc ttcagcaaga agcagatttt tatggctcta tggatggagc aaataagttt
    51721 gtaaagggag atgccatagc aggtcttata gtaacagcaa taaacataat aggtggaatt
    51781 gtaataggag ctgtaatgct gaatatgact cttatgggtg cagcacagac atatgtaaga
    51841 cttactatag gggatggtct tgtaagccag atacctgctc tattaatatc tacatcagca
    51901 ggtataatcg taacaagagc ttctactgat gaaaactttg gtggattagt aggtaaacag
    51961 ttaacagcaa taccaaaagc agtaatgatg actggctgtg ttctaatcgt acttggtatg
    52021 atgcctggat tacctaaacc agcatttttt tcactaggta taggtgctat agcagcaggt
    52081 tactttttag gaagagaaaa gaaagatact ttagaagact tggagtttga aaaacctgat
    52141 atggtaaatc cagataaaaa tgaagtagaa gatgtaacaa acttaataaa tgtagaatca
    52201 atagaagtag aaattggata tggtttaata tctttagctg atgaatcagc aggaggagat
    52261 ttacttcaga gaatagcatc aataagaaga caatgtgcaa tagacatggg tatagtcgta
    52321 caacctataa gaataagaga taatttacag ttaaatccaa accaatacaa tataaaaata
    52381 aaagggaatg tagttggtgg gtatgagata atgcctaata tggttttatg tatggatcct
    52441 atgaatcaag gatttagtat atttggaata aagacaattg agcctacttt tggaatagag
    52501 gcactttgga tagaaagtga caaggtagaa gatgcagagc taaagggtta tacagttgta
    52561 gattcatcca caatacttat aactcactta ctagatataa taaaatcaaa tgcacacgaa
    52621 ttactgggaa gacaagaagt taagactatt atagatgcag caagagaaaa ttatagtgct
    52681 gtagtagatg aattgatacc agatttaatg acacttggtg aaattcaaaa agtacttaaa
    52741 aatctgttaa gagaaaaagt aaatataaag gatagagtta caatacttga gacacttgca
    52801 gaccagtcta gaaatacaaa agatatagag cttcttactg aatatgtaag aatagctttg
    52861 gctagaagta tttgtaataa tttagttgat gaagataagg caattgtagt ggctacattg
    52921 tctccagaaa ctgaagaatt ggtatctaat aatttacaaa ggtctgtaaa tggaacttat
    52981 ccagcagttg acccagaaaa tacaaataaa atatttgaga gtatacaaga agtaatgaac
    53041 aatgtatatt tcaatcataa tataccagta atagtagtat caccaaagat aagagctcca
    53101 tttagaaaat tagttgaaat tgtatatcct aatttgactg tattatcatt aaatgaaata
    53161 cctaacgata ttaaaatcaa agcagaaggt gtggtgagca tatatgatga cgaaaaagta
    53221 tacagctaac acaattcaag atgctatgaa tctagccaaa atggaattgg gtgacaatat
    53281 tacattaata gataaaaaag aggtaagaaa atctggaata agaggcattt tttcaaagaa
    53341 agatattgaa ttgactattg gatgggaaaa gaaagataat ttagaacaaa aagatttaaa
    53401 acgagagata gaacaactaa agtcaattat aaataatatg gggtttgata ataaaaatga
    53461 taatgatata gataaaatat gcaagaattt actaaactta gatttaaatc aagaaattgt
    53521 agaatttata aaagctgatt tacaagaaat gaagttcaat ggaattgata caagtaaaaa
    53581 tttagtagaa agtctaaaga aaaagattaa aatagaaaat caagcaataa atggtaaaat
    53641 tgctttagtt ggaccaccag gagtaggtaa aacgactaca atagcaaagt tggctgccaa
    53701 attagttttt gaggaaaata aaaaagtagg agtaataact atagatacat acaggattgg
    53761 tgctgtagaa cagttaaaga tatatactga tataatgaat attcctttta aaggggtaat
    53821 aagccctgat gagatggaat tggcacttga tgagatgaaa gattgtgatg ttgtattaat
    53881 agatacaaca ggtagaggct ataaaaactc tatgcaaata ttagaaatca aaaatcttat
    53941 agataaagct gaaactgata atatacattt agttttgaac tgtacaacaa gagaaagtga
    54001 tacaaaagca attatagatt catatagaaa tgtgaatttt aaaagcttaa taattacaaa
    54061 gttagatgaa acaataacat atggctcaat atttaacata atgaattatg cacaaaaacc
    54121 aatatcatat attacaacag gacaaaatgt tcctgatgat attataaaac ctaatgaaga
    54181 taagattata agattactat taggagttga aagtatatga tagaccaagc tcaaattttg
    54241 agaaaaatgg caatggaaaa aagaggttct gatgagatta tagtagagaa tgagaatatg
    54301 cctaagataa ttacaatagc ttctggtaaa ggcggcgttg gaaagagtaa tctcgctaca
    54361 aatttgtcta tatgcttaac caaacttgat aaaaaagttc ttatattaga tgcagatata
    54421 ggaatgtcta atatagatat aataatgggg gtaaatgtaa aagggactat aattgatgta
    54481 attaatggcg aaaaaaatat agaagatata atttcacaga ctaagtatgg tgtaaatata
    54541 atatctggag gttctgccct taatcatata gaagacttta cagaagctca aagaaataag
    54601 tttatacata gcatagaaca gattcacaat gtggatttta taataattga tacaggagct
    54661 ggtatgagca aaagcctatt gtcatttata tactgtagta ctgaattttt cttaataaca
    54721 actccagaac cgacatcatt gactgacgca tatagtttat taaaagctat aagtaatttt
    54781 ggcataaaga aaagtgcaaa tataataatc aatagggtaa ttgatttaga agaagcgaaa
    54841 tctacataca aaagaataaa aatggttgtg gacaaatttc taaaccttaa tctggaattg
    54901 tatggatata taatagatga caaaaaagta ggtgtatgtg taaaaaaaca gataccattc
    54961 attttagaat atcctacaag tattgcatca aaatgtatta tagctatagc aaagagaatg
    55021 gtaagtcagt caagagaaga tattgttgat aataaaagtt ttctaagaaa gatgtttagt
    55081 atatttaaaa gctaaggagg cgtagttaat gaatagagaa gaattaataa aagagaatat
    55141 gcctcttgta aagagtatag caagaaaatt ttttatacca gggaaaggtt ttgaatatca
    55201 agacttagta aatagtggag tcattggatt gattgatgca ataaataaat ttgatactga
    55261 aaaaggagca aagttttcta gttactctta tataaagata aaatctgcta tattagatga
    55321 aattagaaat caaagtccaa tttctaaaca taatctaact aaagtaaata agtataatag
    55381 agtggtagaa aagttgcaat ctaaattatt aagagagcca acttcatatg aaattgcaaa
    55441 agaattaaag gtttcagaaa aagaacttca tgatatcgaa agtaatatag atatgttaaa
    55501 tattgtatca ttaaactatg taatctttga agatacaaat gaaactgtac aagatgtaat
    55561 aagtgataga gaagaggaag ctccagaaaa tataatagaa gaagaagaaa agttagagat
    55621 tctatccaaa gcaattagta atttaaatga aagagaaaaa ttaatacttt cactgtacta
    55681 ttatgaagat ttaaatctaa aggagatagg gaaagtgcta ggtgtttcag aatcaagagt
    55741 ttcacaactc cacagaaaat caataagaaa cttaagaaac aagataaaag aacttaaata
    55801 ttctatatag atggtgattg ataagatgat acaaattata ttaatagtag tgtctatttt
    55861 aataatagta actatagtta taaatttaca gaaggaatca aaaaataaag ataacagata
    55921 ctttgataaa atatttgagc aagaatatga agcaaatgat agattaataa ttgcagaaaa
    55981 aagaagattc tttttagaca aagtacttgc agaaaaaaga attaatagtc atataaaagt
    56041 ttatgaaaat tataacctaa taaaggctaa tgaagaaaga aaggaaaaca tatttataga
    56101 atcaaaaaag gaagtaagac aagaaaatga gttatctctt aaagtgaaac atcttataag
    56161 ttcaggttat gatgatgtgg aaatatgtaa gatgctagat attggaaagg gggaactgtt
    56221 attaataagg agttgttaca aaatataagg atattattat gtgataaaaa agtattctta
    56281 ggaataggta ttggtatatt aatatcaact ttatgtataa tgctttttag taataatgat
    56341 atgagtaagg cagagataga aaaaaaggcc agagcgttag gcatgaaata tacaagtgag
    56401 atgaaagttt tagaatagat gatactgttt agacatttac aaaaaaggag gtcataatgt
    56461 gataagagga ttatatacag cagtttctgc tatgataact aatcaacaaa agcaaaatgt
    56521 tgttgtcaat aacctagcta atatggatac aaatggatat aaaagtaaac aacttttgac
    56581 taaaagtttt gatgaattaa agttggaggg ttacaataac tacgcaaatg gaactaaaca
    56641 aaagcagatt ataggcgata taagtccagg tatttctatg gatgaaacta tcacaaattt
    56701 taatcaagga cctataaaaa ctactgataa taaaatggat gtagctattc aaggtaaggg
    56761 attttttcta gttagtgatg cagctggaaa tcaattttac actagaaatg ggaacttcag
    56821 aacagacaat caaggtgacc ttataacaag tgaagggtat tatgtacttg ggacgaatac
    56881 tgctactggt gctgtaggtc atataaatgt aggaaatcaa aaatttgaag tggcaaaaga
    56941 taatacaata tcactagacg gaaatgctat gtataaattt aatattgtag attttaataa
    57001 ctacaataac ttaaaaaaag aaggagataa cttatattct ggaggaggag ctatgaaagt
    57061 aaataatgca cttacaatac aaagtgcgat agagtcctct aatgtagata tggtatctga
    57121 aattaataat atgatgacaa tatcaagaga atatgaggca aatcaaaaga taattcaggc
    57181 tatggattct aaattagcaa aaatagcaag tgagattggt tcagtaagat aggtaatagg
    57241 aggtgaattt ttatgtacac aatgttttat actagtaaaa cagctttatc agcaaatcaa
    57301 agtaaactag atataatatc taacaatata gcaaattctg attcaacagg atataaaaaa
    57361 ataaatatgg aatattctga tttagtggat gaagtactaa atagaccatc ataccctaca
    57421 aatggtaaag atatatcgac tggaacagga gctaaggcaa cagctcccat gagaaattat
    57481 gaacaaggtg cattggctcc tacagatagt aagagtaatt tggcgataga tggagaagga
    57541 ttctttagag tgataagaaa agatggtaca tatgcatata caagaaatgg tggatttaat
    57601 gtagatgctt taggtaagat tgtagatgat aatggaaata tattagatgt ccaatttgat
    57661 gcaggatata actataataa tacaaatata gatagtacaa acctgacagt ttcaagaaat
    57721 ggagagctat tcgtagataa taaaaaaata ggaaaaatta acttatatca acctatagga
    57781 actcaaaatt ttatatctga aggagatagt ttatttgtcg caactgatgc agcacagatt
    57841 aaacaagttg agaaagtcga tatagttcaa ggctatagag agaggtcaaa tgtttcttta
    57901 caagaagaat ttgttgactt aatagccact caaagagcat ttcaaatgaa ctcaaaggga
    57961 ataaagacag cagatgaaat gtggcaaata gcgaataatt taagagctaa ataattatgt
    58021 aaggagagga atattcatga atgatatgaa agagtacgat tttggcaaac ctcagagtta
    58081 ttcaagagaa aatttaactt gtttaaattt tttattagct gaattttgta aaaaatataa
    58141 aaactatata atttatgaac ttaagtgtaa ttctagtatg gttgttgata gtatagacca
    58201 agtaaattat cagacttttt tagatagagt aacttcttca tgcgtagtag tacaaaatgc
    58261 aatggaacct gttatgaaaa acttttcttt tagaatagat agaagtgtag ctgatatgtg
    58321 gattgatata acttctggag gaactggagt tgtaaaggat aatgatagag agcttacaga
    58381 acttgataaa aaagtgcttt tacaccttat ggatgattta gtaagaaata tgcacttatt
    58441 tgagggtttt gaaaatatac aagtattgga tacacataca catattaatt tgccacaatt
    58501 atgttctcca actgcaccag tatgcgttgt agatttaaaa gtgctaaatg ataatgagtg
    58561 tattggaagt gtttctcttt gttttccata caatggttta gaggctctgt tagaaagtat
    58621 atctgttata gaattttttg ataatgatgt aggagatgat tcagaggaat ttacccaaaa
    58681 aatctataat agtgtatcta atatagaatt atcagttatt gcagagatag gaaaagtatc
    58741 aattaatgtt gaggatttac ttaaactaga agttggagat gtaatagtaa caaataaaaa
    58801 aataaatgat tatatagata tatttgtaga aaattcaaaa tcatacacag caacaccagg
    58861 atttatatca agtaaaaaag gtgtaaaaat aaatgatgct gttggaaaag aggtgtagtt
    58921 atggacaata gtaatcttat ttcagatgaa gaagcaaaga tgttattaaa tgataaagtt
    58981 gaaagtgaag ttgatggaga tgatgagtta gccttagatg tctctgaagt taatcgaaat
    59041 aatatacaaa ggatacttga ccttaagtta gaattatctg tagttatagg aagaactaag
    59101 atgactctaa gagatatttt aaatttacat aaaggttctc ttattgaact ggatacttta
    59161 gcagaccaag atgtggaaat actaatagat aataaggttt tggcttatgg aaaagtagtg
    59221 gtggtagatt taaattttgg tgtaaagata acaagtatag taagtgaaga agacatggta
    59281 aaatctcttg tttagagata acatcaatta atacttaagg catgaggtgg tacttatttt
    59341 aaacttaaat gatataaaaa aagatatact aaaactcaat aaaaaagact catgttctct
    59401 atataatgaa tctattaata atataaataa taattgtata tcaactggat taaaattttt
    59461 aaaacaagca agagatttaa acccagatga tgttgatata ttaaatctca caggtcttgt
    59521 aaacttacta aaatgtaatt ttgatgatgc tgtagaaagt ttctataaga gttcactttg
    59581 tgaaaaaact gctctgtgtg aaaagtatat aaacatgctt acatctgagg agtttttaat
    59641 tttctttgaa aagtacaatc aacttataag gttaataaat aaaggaatgt ataaagaagc
    59701 tatacaaggg tttaaactca taactgacca atactgtgat ttaatagaac cttatgagtt
    59761 gcttgcctta ctgtatgaca aggaagaaga atatataaaa tttgatgaat gtttagaagt
    59821 attgaagatt attgataagg aaaattattt attaaatcaa gaaaataaca cattagatat
    59881 gtataatagt gctaatatac aaactaaaag taatataaaa gtagatgatt ataagaatga
    59941 gttcttacat aaaagtagta gtaaccataa aattaatgat tataatgatg taactaaaga
    60001 aaagagttca agcaaaaacc agaaaagttc agattctaat aagaaaaaaa gtattaaaaa
    60061 aaataagtac ctatatatag ccataatatt aggaatatta ttagtaggac aaagtatata
    60121 taattcttat aagatgaata atttaactga taaaatatct aaaaataatg aaactaaaaa
    60181 tgaagagtca atagattcta acttgactaa gaaagaaaat aatatagaag aaaatgaaga
    60241 tatgagtaag gcttctaata taaataagag taataaaaac attaataaag aggatgatgt
    60301 aaaatctaaa aaaaatactg tagaaaatga agatgataaa gattctgact tatttacaga
    60361 ggatgaattg atgtctaagg cgaatacttt aaaatcagaa aagaaaacta aatcttctat
    60421 acaactatat aagaaagttg cagatatagg tgaaaataaa gggaatacat ctgaagcaac
    60481 ttatcaagtt gctattctca gtgaaaagtt aaaagactat aaaactgctg aagaatatta
    60541 taaaatgtat gtagaaaatt actcagaaaa agatgcttat tttgatgaat cttattataa
    60601 tttaggtatg atgtactata acaatggtga tttaaaaaat tctaaattga cattaaagaa
    60661 gttggttaat aaggtaccaa atagtatgta taataattca aaagtaaaag aaattttaaa
    60721 agaagaatag ttaaattaga taagaaaaat aaattatttt attttaaaat aatatgatta
    60781 taatatattg acataccatt ttaaaaaatt taaaatatta attataaaat gaggagggat
    60841 aaaaaatgga atttgaaaaa gggagtattt caattcatac agaaaatatt tttcctataa
    60901 ttaaaaaatg gttatactct gataaagaca tatttataag agagcttata agtaatggat
    60961 gtgatgcagt aagtaaacat aaaagacttg tatcactagg agaaatatca gaaaataagt
    61021 catcagatta taaaattaca gtatctgtaa ataaaggaga aggtacactt aaatttattg
    61081 acaatggaat tggtatgact gaagaagaga taaaaaaata cataaatcaa gttgcttttt
    61141 caggtgctga agatttcttt aataaatata aggataaaat ggaagagtca aatgatataa
    61201 taggtcattt tggattagga ttttattctg catttatggt gtctaaaaag gtacaaatag
    61261 atacactttc atatacagaa ggagcgactc ctgtaagatg gatatctgaa ggtggtacag
    61321 aatacgaaat atctgaatca gatgctagaa atgatagagg aactactata acactattta
    61381 ttgatgatga tagtaaagaa tttttagatg aatttactgt aagaggaata ataaataaat
    61441 actgttcttt cttaccagta gaaatatatt tagaagatgt tgaaagatta gaaagagaag
    61501 ctaaagaagc agaagaaaaa gctaaaaaac aaaaggaaga tggaaaagaa gagattgtag
    61561 atgcaaaagt aattgagcct ttaaacgaca ctaatcctct atggttaaaa tctccaaaag
    61621 actgtactga tgaggagtat aaagagtttt atagaaaggt attcaatgta tttgatgaac
    61681 ctttattttg gatacattta aatgtagatt atcctttcaa tttaaagggt atactttact
    61741 tccctaaatt aaaaaatgag tttgaactga ctgaaggaaa agtaaaatta tacaacaatc
    61801 aagtgtttgt ggctgacaat ataaaagaag ttataccaga atttttactt ttattaaaag
    61861 gagttataga ctgcccagac ttaccattaa atgtatcaag aagtttctta caaaatgaca
    61921 gggatgtaag caaaatttct aaacatataa ttaaaaaagt agctgataag ttaaaatctc
    61981 tttgtaaaaa tgaaagagaa gaatacaata agttttggga tgatatacaa atatttatta
    62041 aatatggttg cttaaaagat gaaagtttct atgagaaggt aaaagaatgt atattattca
    62101 aaactattga tgatgagtat ataacattac aagattattt agaaaagtgt aaggacaaac
    62161 atgaaaataa ggtattttat gtaagtgata aagaacagca atctcaatac attaaactat
    62221 ttaaagaata cgacttaagt gctgttgttt taaactcatc aatagatact cattttattt
    62281 catttatgga atataaagag aatggagtta agtttaatag aatagatgca gacctttctg
    62341 atgtattaaa agataaaaat gaaaataaag atagtgaaga aaacaaagaa gagatagcta
    62401 agatagaagg tctgtttaaa gaagctgttg gagaaagagt gaagaattat tctgtagaag
    62461 gattgaaaaa tgaagacact ccagctatgg tgttagtatc agaacaatct attagaatgg
    62521 cagaaatgca gtcaagattt gctggaatgg atttaggaat gaattttgaa gaagaaaaaa
    62581 ctcttgtaat aaatgagaac agtccaataa tcaaaaaatt ggtttctctt aaagatgatg
    62641 aggaaaagaa agataagatt acgcttattt gtaaccagat agcagattta gctttacttt
    62701 ctaataaaga attaaagcca gatgagttag attcatttgt acaaagaagt aataagctta
    62761 tgagtctttt gatagaatta taagattgaa tttgaataca ttgaagcaaa tttataaaaa
    62821 gtattcaata tcagtgataa gaaagaagtg tctcaaaatg aacttttcag ttcatgaggc
    62881 gcttttttta tgtgaaatta aatttatttt aatcatttca acaatgaaaa atatatttat
    62941 ctctattttg agacagaccg ttctttattt ttttatcttt ggttaatttt taaatattta
    63001 agtaggttct aataaaaaac tctatttagt taaatatagt taacttgata tataataaga
    63061 taatacatat aattaagtaa aagattgttt tttagtttat gtttaaatac ataattacac
    63121 tttgttaaaa acataaaatt attactaaag tagaaatagg aggttttagc atgaatttta
    63181 attataattt gccagtaaat atcttatttg ggagcggcag aattaatgat gtgggaaaag
    63241 aagtatctaa atatggcaaa aaagtattga tagtaacagg taaaaatagt acaaagaaaa
    63301 ctggattact tgataaaaca atagatttac taaaagactc taaaatagaa tatgaagttt
    63361 ttgatagagt agaacaaaat cctcttataa ctactatata ttcaggagta gaaattataa
    63421 aatcaactgg atgtgattgt gttttaggtc ttggtggtgg aagcattatg gatgctgcca
    63481 agagtatagc tttttcttat aaaaacccag gagatttaaa tgattatata tttggaatta
    63541 gacaaggtga agaagcttta cctataatct tagttccaac aacatcaggt acaggtagtg
    63601 aaggaaattg ttttgcagta cttacaaatt cagaaactaa agataaaaaa tctataaaga
    63661 agaatagtat gtatgcaaaa gcatcaataa ttgacccaga acttatggtt acaatgccaa
    63721 aacatataat tgcatcagtt ggatttgatg cacttgccca taatatggaa gcatatcttt
    63781 ctaatggaag aaaccctctt gcagatgtac aagctattta tgggattgaa cttatatcag
    63841 aaaacctaat aaaggtatat aatgatgtta atgatttaga agcatgggaa aaaataacac
    63901 ttgcaagtac tattggagga atgacgattg gtacagcggg tacagccttg ccacatggaa
    63961 tggagcatcc tgtaagtggt cttagagatg taatgcatgg aaaaggactt gcagctttga
    64021 ctcctactat tatagaaagt tcatgggata gtgatattga aagatttggt aatatttcaa
    64081 aggtattagg aggaacttgt gcagaagatt gttcagatgc aattagaaat ttccttaaaa
    64141 aaatagattt agatataaag ctaagtgatt taggtattga aaaatcagat atagattggt
    64201 taactgataa ttgtatgaaa atatcagttg caaatattaa gagacatcca aagtatttta
    64261 ataaggaaca aataaaggaa atgtaccata agtctttata atttgacttt acatatttag
    64321 ttttatataa aaattataaa ttaataataa aaaattataa gtaattaata gtaaaaaaat
    64381 tgtgtataga agttatatat ataataaatt tgtcttaagc ttttatttta ctttctaata
    64441 aataaaggag tttaaaaaag ggaagattaa ttaagtaata ttttataaaa ttcttcgatt
    64501 taaaaacttt aagtagaggt gaaataaatg tttaatccca aaagaataat attcgaaaaa
    64561 ggaactttag acactgatgt gggtaaaaaa atatacaata aatttagaga taataaagat
    64621 gtagagataa ttaatatatc atcaaatagg attaaagaac atattccagg tgaaaatcta
    64681 tatgaacaat atagaagtgg gaagcagact atggtagttg ggattagaaa aagtctgaag
    64741 tttcaaacat gtaaaccttc tgctaattat caactaccac ttgtcagtgg atgtatggga
    64801 agatgtgagt attgttattt gaacacacaa ttaggtgata aaccatttat aagggtgttt
    64861 gtaaatgtag atgaaatact tgaacagaca aaaaaatata ttgaagatag aaagccacag
    64921 gtaaccatat ttgaaggggc agctacatca gacccagttc cagtagagcc atatactaat
    64981 tctttgaaga aaacaataga gttttttgga agagaggaaa aaggaagatt tagatttgtt
    65041 actaaataca gtgatgtgga tagcttattg gatgctgaac ataataatca tacagaaata
    65101 cgatttagta tcaatactcc tagaattata aatgaacatg agcattatac agcctctgca
    65161 aataaaagaa tagagtcagc tgtaaaactt gctagggctg gttatcagat tggtttcata
    65221 atagcacctg tgtttttata tgaaggttgg aaagaagagt ataaaaatct gattataagt
    65281 ataaaagaag ctttaccaaa ggattttgat aaaaaaatta tatttgaagt tatatctcat
    65341 agatatacaa ctaaagcaaa aaatagaata ctagagattt atccagatac actattgcca
    65401 atggaaaatg aagatagaaa gtttaaatac ggtcaatttg gatatggtaa gtacgtgtat
    65461 gataaagaac aattagatga tatgaaagag ttctttctta aggaaataaa tggagtattt
    65521 aaaaatagtt taataaaata tataatatag caaatcttac ctaaagattt gctatatttt
    65581 atttttatat attttatgtt tataataaag caatgagatt tagcattatc atataagaaa
    65641 attaaaaagg gcactatcta tcaagaacat tttttctagt tttgatacta taaaggataa
    65701 gagtaacaaa aatatcagga ggagttatag tatgcatgca tgggagtcta ttcaaattac
    65761 attggattta atagaagcaa atttatcaga agaaatatca attaatgaat tagcaaataa
    65821 agcaaattta tcaccatttt actatcaaag actatttaaa agattggtaa ataagactgt
    65881 aatggagtat ataaagcttc gtcgtcttgc aagagcttct gaatacttag cagaacataa
    65941 gaatcgtata cttgatgtag ctttaaattt tggatttgct agtcatgaga catttacacg
    66001 ttcctttaaa aaagcatatg gattaactcc agaaaaatat agagcaaatc cagtaaaact
    66061 caatcatttt attaagccag aattaatttt aaattatgct atggttgatg aaggtgttcc
    66121 actgattgca gatgatatag tgattgaagt caatcgtaag acattgagta atccaaggac
    66181 atttgttgga atagaaatag aagtacctat ttgccagttg gtgggcggtg aaacaactgg
    66241 aattgcaata gtagaggaat tatggatgaa acttggaagt caaagacata atataccaaa
    66301 tcaaattcca ggtggaaatg aatttgctgc tctttatatg ggaaatgcaa aagaaggaaa
    66361 ttgtatgtat atggcaggtg tagaggtaga gtcaggtaca tcagtagaag gatatagtac
    66421 ttttgagttg ccagctaaag aatatttagt atgtggattt gaggcagaaa actttaatga
    66481 gttagttaat tcagctgttt ttaaagcaga taaatttatg gaaagatgga tgaagaaaca
    66541 taatttaaca actactgatt ttgcaattga gatgtattac cccactacac ctgaagcagc
    66601 atatctggaa cattggattg ttccggttcc tattgaacaa tagaaaggat gatgaatatg
    66661 aattggcaag atgcgttttt tcaagatact aaacctacat ttgagcaaat taatgaattt
    66721 attaataatc cattatggga caagttaaat aaaactttgg tttctactta taatgtagaa
    66781 cctaagcttg aatacagtaa atgttcaatg caaagaggtt ggaatgtaaa atataaaaaa
    66841 agaggtaaat cactatgtac tttatatcca caagaaggtt attttaaagc tttggttatt
    66901 gtaagtgaaa gcaatagagt agaggttgat ttatttatta atacttgttg tgattatatc
    66961 aaaaaaatat ataatgaggt aaactttttt aatggaagta aatggctaat gattcaagta
    67021 gatagtttat tggtattaaa cgatatgctt gaactaatta aatttagagc ttaacatata
    67081 gaacaggatg aatatataag tcatcctgtt tttatattca atcagataaa ttaatatata
    67141 gtctataata tgaataattt agtaaattta aatttacttt atctttctac attctttgca
    67201 actaagtcca catgtgtttt tttcttgcat attagtagca ccccaattag caaattgttg
    67261 taaaataggc acaatacttt tacctttact tgttaatgta tattcaactt ttggaggaat
    67321 ttcattatat tgtttacgat gaacaatacc agtagactct aaatctttta atgattgagc
    67381 tagcatagta tttgtaatgc catccaattt tctttttatg ctactatatc taattggatt
    67441 ttcaactgct aacatacata taataggtaa tttccactta ccaccgacaa tgtctaatgc
    67501 ataacggatt ggacaggtta attcttcaac gtttttagtt atattttttt cagtatttat
    67561 actcatttta attactcctt agttatagta gtatcttttt tatactttat cagaaaaaac
    67621 tgcatacttg ttttttctgt attttatatt aaaattatat caaaggataa tccttaatac
    67681 aagtatttaa aaggggtgta agaattatga aagcattaga atttttgaac aaggcaggag
    67741 tttattattt agcaacagtt gatgagaaca atcaagcaca tgtgcgtcct ttaggatttg
    67801 ttatggaata caatggtaaa cttacatttt gcacatctaa tcaaaaggat atgtttaagc
    67861 aacttatttt taatccaaag gttgaacttt gttgtataga ccaaaacctt aatactctac
    67921 gtattttagg tgaagcagta tttgttacat caaaagaaac acaagctaag gcacttgaaa
    67981 taatgccaag tttaggtcag atgtactctg taggagatgg taagtttgaa atattctcta
    68041 ttgataaggc aaaagttagt tgttgttcaa tgagtggtaa aaagattgat gtagagcttt
    68101 aattataatt gaatcgacat ccatagcgaa aattaagaaa acgttattac tgaaatattg
    68161 atagatttaa tttaaatgca ataaaaagat ttttaactaa tgaatatgta aaaattttta
    68221 gttattagat gtgtatttca ataatgatat actattttga ataattacat actagaaata
    68281 agataattaa aatttacttt ataatgggat agatttcttt taaaaaatat tttaactata
    68341 attgattttt atttaatctg aaaaaaatat tatgactata aaaaattgct acttattatt
    68401 tggatatttt tatatataaa taataagtag catgacttta tacattaata atgatagaat
    68461 ataaattaat agataagata tgattttaaa aggagtgata taagatgagt aaatatagtt
    68521 ctttatggga atatgttaag aaaaacaata gtcaatcgtt taaattaact tttgaagaaa
    68581 taaaagatat tgctgggata gagatagacc attcgttttt gaaatataaa aaggaattaa
    68641 atgaatatgg atatcaagta ggaaaaatct ctttaaaaga gaagactgtt attttcgata
    68701 aaattggtta agacataaat aattacatat aataaaataa tttgtattga tgattattac
    68761 aaataaaaat aaagtaaacc ttatataaga tttactttat tttagatgat tctttttttt
    68821 agctttatac tataaggtat ataaaactaa gcttattaaa aatgttataa tttctattgc
    68881 tatcatagac catatcaatc catcaagttc ataaaagtaa ttaagcttta ttaaatagct
    68941 tctttattat aatttcttta tttcatataa tataaatagt attaaaattt ttatgggagt
    69001 taaagtaagc atgtattatt acttagatat ttgtataatc aacatctagt aatttacctt
    69061 tttgatgaaa atgattaata agttttttag gataattcat tattaattca tctggaaaat
    69121 taatttcctt taagatattt tcagaatact catagttacc tatgtcaaaa caaatgtgag
    69181 catctgaagt tagtatgatt ttagcaccat attttttgca aagtgtagca atatacttac
    69241 agttatccga gctaccattt cttgacacgc ctttaataga acaattattt atttctatta
    69301 agatattctt ttctatagct aatttaatga ttaattcata gtcgattggg tagtttgggt
    69361 ttccaaggtg tcctaatatt tcaatattat catgcttatt tattgcattt attaaagctt
    69421 tagtattatt ctctaatgta tttggagaaa acacagcttc gtgaaatgac aagataagat
    69481 aatctaaccg aggaattaca aaaggctcta ggtctatgtt tcctttaata tctagtatat
    69541 ttgcttcaca gcctcttaaa attataatgt tatttatgat tcttgggata ttttgaatgt
    69601 tgtgaaagta ccatctgtgg ggagaaccag gcatcttagg accatgttca gatgtaccta
    69661 gtatcttaat tccattttct ttacaataat taatattttc tagtaaagtg ctatagccat
    69721 gaccactgac tatagagtgg gtgtgtaaat ctgataaaaa attcatataa attcctcctc
    69781 tataaaagat gagggtaacg taatttatat tataaaacga ataggaaaga aaatcaatag
    69841 ttacataatt agacaaaaat attaaaatat tgtagaatta agcttaataa taaatgttta
    69901 acagtattac tgcttatagg ggaggttaac tatgacacaa aagaagctat caaggaaaga
    69961 aaaagtttta atttgcttga aaaggttaac agaagaacac ttgaacttta ataatggcat
    70021 tagatttgga tttgatgcag aatatatagc tactgaagta ggtataaata gaagtaatgc
    70081 tagtaaggaa ttaaatcaat taataaaaga aagtatcatt ataaagataa agggtaagcc
    70141 tgttcagtac ttatataaag aaagtattga gagtatttta ggaaagaaac taaataaagg
    70201 gatatttgat aatattaact ctataaacga atatagtgaa aatgattcta tcaaagatga
    70261 gtatatttta gagagtataa aaaaagagaa caatattttt aatttagtag gatgtgatgg
    70321 aagtttaaga tcccaaatag aacaggctaa agcagcagta atatatccac ctaaggggtt
    70381 gagtacatta ataataggac ctacaggagt tggtaaatct atatttgcag aatatatgta
    70441 taagtatagt ttaactataa aagaagatag tgataatgca ccatttatca tatttaactg
    70501 tgctgattat tctgataatc agcaattatt attagcgcag ctttttggat atgtaaaagg
    70561 agcatttact ggagctgata aagataagta tggtattgta catgaagcta ataatggagt
    70621 attgttttta gatgaagttc atagattatc tgcagaggga caagaaatgc tatttctgct
    70681 tatggataaa gggatatata gaaggttagg agaggctaat aaggtacacg agtgtagagt
    70741 tatgataatt gcagccacta cagaagaccc agaaacagca atgttggaaa cgtttttaag
    70801 aagaatacct gtaactataa agattccgtc tttagaggaa agaggctttc aagagagaat
    70861 gaagcttata tgttattttt ttaaagaaga gagtgttagg attggtgtta agttaaaggt
    70921 ttcaaaagaa gttattaagg catttatttt atataagtgt aagggaaaca taggccaatt
    70981 aaaaagcgat atacaattaa tttgtgcaag agctttttta gattatatga cctataaaag
    71041 ggaatgtgta tatgtaaggc tctctcttct accaaataat attagagaat cattatatgg
    71101 aaataataga aaagaggagt ttgtacaaaa tttcagtttt attggaaaag atgatattat
    71161 ttttttacca gaagaaaagg attttgaaag tgaaaattta ttaatagaaa ataaaaaata
    71221 tgatttagat ttttatggaa tgataaaaga aacttggaat aaacttcaac aagaaggtat
    71281 taaagagtca caaattagaa gtgttataga tggagacata cagaagtatt cctataattt
    71341 aatgaatact tttatatata atagtagtaa tcaaacagct tataacaaca ttgttaatga
    71401 ttcaattgca actactgtaa aatatatttt acaaaagcat gataaatgga gcaaaagaga
    71461 aggattagat aaattaataa aagctatagc tttacatatt cagaatttaa ttgaaagaat
    71521 aaagattgga aatatagtaa agcatcctaa taaagatgaa attatgaagg aaagagcata
    71581 tgaatataac atagcaaaag aaatattatc taacatgtca ttaatgtatg gagtagagtt
    71641 tccagaagat gaagcaattt ttttagcaac atttctttat ttatcgtatg tgggattaaa
    71701 tgaggagagt atagcaatat tagtcataat gcatggtgaa tctacagcat ctagcatggt
    71761 gaatgtagcc aatactttac tggattgtaa ccatgcagtg gcaattaata tgggattaga
    71821 agatagagtt caggatattt tagtacaagc tgtagaaata gccaataaaa ttgataaagg
    71881 aaagggaatt ttaattttaa ctgatatggg gtctatttta acatttgcta aagttattcg
    71941 tgatgctaca ggaaaagaag taaaagcaat agatatggta agtacaccta ttgtaataga
    72001 agcaactaga aaggctctaa ctccagaaat gacattagag aaattatatt ttaatattat
    72061 agaatctata aagaaacatt atggagatat ggaagttaca tatgctgaaa aagataatgg
    72121 tggtagatat tttgatagat tactaattga taatattagt aaaactttga cttttttaaa
    72181 tggggaaaag gcttatttta tattaaaaga agtaattaat agaattagtg aacactattc
    72241 tttagtaatt caagatgaac ttttagtaaa gtttatattt cattgttcat gtatgattga
    72301 aagagtaata ataaaagagt ctttagttta taaatcatat gaagaaagaa ttagtagaaa
    72361 taaagaatta tatttagtta taaaagaaag ttttaagcta gtagaagaga cattcgatat
    72421 aattatttca gatatggaat atgcaaatat attagatata tttgaatcac aatatgatac
    72481 agataaattc aaaagttgat acaaaattta aaaatagcca aaaggctatc ttttttttac
    72541 tttttttgat acagatttga tacaggttga aaaaatcttt tgatacatat cgaaataata
    72601 agtttttaaa aaaaattgaa taaaaagttt tgattaaatc ctgtaaaata gccatttgtt
    72661 attgatacac ataagttggc acggcaattg cttatataaa aagtgacaag aaaagtgagg
    72721 tgaaattggt gataggaata atagttatga ctcatgggag ttttagtgaa gaaattataa
    72781 aaagctgtga acttattgca ggaccagcag aaagaacagc agcaattaaa ctaaatagga
    72841 atgataatat tgaagactta aataaaaatt ttgtagaaaa gttaaatgaa ttagatgaag
    72901 gtgacggagt tttagtatta gctgacctat taggaggttc gccaagtaat gttgcaagtt
    72961 taaaccttaa aaaaggtggc aagtttcatg cacttactgg agtaaatctt ccaatgctac
    73021 ttgaagcttt aattaataga gagggaaaaa gtttagaaga gttagcagaa gcatgtattg
    73081 aagcaggaca aactggtata aacaatatta acaaagttct tagctcaatg taatagaaaa
    73141 aggagtttga ttaaaaatgt ctttagtaaa atattgcaga tgtgatgata gattaataca
    73201 tggtcaagtt atatataaat gggttaagca tctaggtgta aaaaagatag tagtagtaga
    73261 tgatgaaaca accaatgatg ttattgctaa aggtttgata aaaatggcag caccaaagaa
    73321 tattgattta tcaatattaa ctgtaagtga atcaaggaga tatttttata ataatcaagc
    73381 tgatgataac gtttttgtat taattaaaaa tttagatact gcaaatagaa tgatagaaga
    73441 agggattaat atcaaaaaac ttattgttgg aagaatacct acaggaatag gaaaaaagaa
    73501 aatatctcaa aatgtataca ttaataaaaa agagtttctt ttaatagatg aatttattaa
    73561 aaagaatatt aatgtatcaa ttcaaatggt acctgatgaa gaagaagtag aattaaacca
    73621 aaatattaat cgctataaag gagagtttat ttagcaatga ataaatataa ggtaatcata
    73681 ctgtgccatg gaacttgggg aaaagtctta gtagaagaaa caaataaaaa ctttggattg
    73741 tcaaatcaat atgaagtttt atcactaagt tctgaaaaag atgtttctgt atttatgaaa
    73801 gaggttgaag aagtagtaga taaagaagat gtgaaaatta taatatcaga tttatatgga
    73861 ggatctacat caagtgttgc aatagctgtt gctataagaa gaggaataga tgcaataaat
    73921 ggacttagct tacagacaat tttaatcgta gatgaagaat taagcaaaga agataaatta
    73981 catacattac cagaaagaat cgtcaaaaaa aataataacc tttgtgtgga tttaattaaa
    74041 gaatttaaaa aaatataaat tatgaggtga atataatggc aaaaataaca ttagtaagag
    74101 tagaccacag attaattcat gggcaagtta taacaaaatg ggtaaaaatc gctcaagctc
    74161 aaaaaataat aatagttgat gacttcttag gtcaagatga atttatggct gacatatata
    74221 aaatggcagc accatcagga gtagaagtag ttattttaac agcagaagat gcgggacaag
    74281 cattccaaaa caacacttta ggagataaaa atatatttat tctatttaaa aatgttgata
    74341 tggcaaataa ggcttataaa gctggactta aatatgaaaa gattcaatta ggaggtattc
    74401 caaatgaagc aggaaagaaa atggtgttta cagctgtttc attaggaaat gaggatgtag
    74461 aacaacttaa tgaacttaat gaaaatgggg ttgaaatagt cctacaagtt ataccagagg
    74521 aatcatctat gacatatgaa aatgcgttaa agaaatttaa ataaaaaata taaattagga
    74581 ggaattataa atggaatctg ttttgatgtt ggcaattgta acaggattat ggtattggtt
    74641 tgcagcaggt cttgcagggt ataccctttt ctcaacacta aagtctcctt tatttatagg
    74701 ttttagcctt ggattacttt ggggtgatgt aacaactggt atgattgttg gtgcaagtat
    74761 agaaatggtt tatctaggaa tggtcgcagc agggggaaat attccatcag ataaatgtct
    74821 agctgctctt attgcaatac cagtagcact tcaaactggt gttaatgcag aagttgcagt
    74881 atctattgcg gtacctttag gtgttatagg agtattagtt aataacttaa gaagaactgg
    74941 taatgctgta ttggttcata aggcagataa gtatgctgaa gaaggtaata caaaaggcat
    75001 ctggagatgt gcaacacttt attctttaat atttgggttt gttttaaggt ttccaatagt
    75061 ttttgtatgt aacttttttg gagcagattt agttcaatca ttattagatg ttataccaca
    75121 atggttaatg aatggattaa cagtaatggg cggtatatta cctgcattag gttttgcaac
    75181 aacaatattt actataggta aaaataaatt tttaccaatg tttattatag gattttttat
    75241 ggttcaatat tttgaaatat caattactgc agctgcaata tttggtgttt gtatagctct
    75301 tttaattacc tttatgaaag aagacaaaag ggtaggtgaa gtataatgca agaaataaaa
    75361 aataaagaag ttaaaaatgg acaaggtcca actgaagtta ataagacaag agtacttaca
    75421 aagaaagatg taacaaaaac atatctaaga tggtggtgga cagcagaatt atccaactct
    75481 tttgaaagaa tgcaagcatt agcagtttgt gcaagtttca ctccggcttt agaaaagtta
    75541 tataagagaa aagaagattt agtagatgcg ttaaagagac acttacaatt ttttaatact
    75601 caagctatat ggggaggatt aattcacggt acagttttag ctatggaaga agagaaagct
    75661 actgaaggaa aaatcccagg agaagttatt tcaggtgtta agaatggtct tatgggacct
    75721 ttggctggaa ttggagatac tttagatttt ggtacatttc aaacaatatt cttagcttta
    75781 ggtgcttcat ttggagcaga aggaagtgtt ataggtgcat ttttcccaat aatgtttagt
    75841 atattactat tttgcgaagg ttattactta tttcatttag gatattcttt aggtagagat
    75901 tcaattaaga aaattctatc aggtggtatt gtcaataaga taattgatgg tgcttcaatt
    75961 ctaggaatgt ttatgatggg agcattatct gcaactacag ttaagctttc aactccgcta
    76021 tcatttgata ttggtggtaa agcaattgtt gttcaagata cattaaatat gattgctcca
    76081 ggtttattac cacttggtgt tgtattcttc gtatattggg gaatgaaata caagaagtgg
    76141 acaataacta agttattagt aattttagtt gtattagcat tggtagggtc attcattgga
    76201 atattctaat tcacagtgat taaaatatag aatttaattt taggaggaga aagaaatgtc
    76261 agaaaaaatg tatacagaaa aggaatattt agaaggaatt agaggagcaa caggagaaag
    76321 agcagtatgg ttctatcttc ttatgaaaga agctgaaaaa ttaggagcta atccagatga
    76381 tatatgtaaa gaagcaatat atggatttgg taaaatgaga ggtcaaaaat ataacgtagc
    76441 agatactcca ggaaaaatgg cagaaatgtt atataacagt aaaggacaaa aagtgtttga
    76501 aatggaatta gtagaaaata cagatgagaa tggcgtttta aaattccatc actgtccatt
    76561 agatgctgct tggaaagaat atggattaac taaagaagaa agaaaagaaa tttgtagatt
    76621 agcttgttat ggggattatg gaagagttga ctgcgcacaa ggtgttaaat tagattttgc
    76681 tcaaaaatgt gctcatgatg atgaagtttg tgaattagta tttacaaaaa aataattttt
    76741 aatgctaaaa gcctgttctt taaggacagg ctttaaaaag atagaaagta ggttgattta
    76801 tggatataag cagaagtgta gataatagtt taaatagaac catagaattt ctaaaagaat
    76861 tgataaaaat tgattcacaa caaggtgaac ctatttcaca atgtcctttt ggtataggac
    76921 ctaaaaaatc tttagataaa actttagatt actgtgctag tttaggtttt agtgttaaaa
    76981 atattgataa ttatattgga tatgcagaaa ttggagaggg agaggaatta atagggattc
    77041 caatgcattt agatatagtt ccaccaggag aggggtggag tgtagaccca ttttcgggag
    77101 cagtaattga caatattatt tatggaagag gtgtaataga taataagggt gctgtatcta
    77161 tgcttataca tgtattgaaa aacatagagg atatgtatcc tacaattaat aaaagaataa
    77221 gattaatttt tggtacaaat gaggagacag gtatgaaatg tatcaaatat tacttagata
    77281 aaggtgaaga aattccaagt atgggattta ctccagatgc tatgtatcca gtggttaatg
    77341 gagaaaaagg aagggttcat ataaggatag aaaaagaaat taaaattgac aaaagtaaac
    77401 cttacataat agtaagggga ggaactaaag aaaatgttgt tccatctcat tgtactgcaa
    77461 aaattattaa tggaattatt tcagagttaa ctactaaagg agtagctgta catgcaagta
    77521 atcctgaaaa gggagaaaat gctatatcta aaatggtaat aaagatagtt gaggataata
    77581 tggattttca gcatagagaa gatatcgaat tagtttcaaa atacctttgt agtgattatt
    77641 atggagatgc attagggatt aatcaatatg atgaggtatt caaaaacact accttaaatt
    77701 taggaatatt aaaagtaaat gaggaaaaaa tcgtatgtga gttagatata aggtatggta
    77761 aaaatatagt tttaaacaat ataatagata gattcaaaaa ggttttttgt aatggttgga
    77821 aaatagaggt tattgctcat aaagacttac attatgtgga tgagagtaat ttagtactta
    77881 aaaaattatt agaagcctat gaagaagtaa cagatgaaaa tggatataca attgctatgg
    77941 gtggtggcac atatgcaagt tggtttaaag atatggtggc gtttggacct aagttcttag
    78001 cgtataaaac tggtggtcat ggagtagatg aaagagtacc aataaatcat atacgaaaga
    78061 atatggagat atatactttg gctttaataa aactattaga attgtaaaag aagaagagac
    78121 tttatgtgca aatttacaga tatcttaaaa agagagataa aacgagttca accttattta
    78181 aatgttcaac accatcaaat ggggctgtct caaaatagag ataagcctct tacttattgt
    78241 tgaaatgatg aaaatatatt ttacttcata caaaaaagag tgccttatga agtaaaaagt
    78301 taattttgag acaccctcat ttgatgatgt tgaagagaaa ataagtatga aattattaaa
    78361 aaagatgatt ttataaaagt taaggttgaa aagaaaagtt aattgaatgg aattagataa
    78421 atggagaagg atgtatacta tctaataaaa taacaaaaga gtgttataaa gttggttata
    78481 tgattagaga aaagtctatt gatacttatc cagatagtgg atggggattt atgacttggg
    78541 atgaaaatgg agaataataa aaattatagt ttatacagtt taataagata tatgtacaag
    78601 cagttaatct aaatgattga ctgcttttct tttatagatt tttatataat agacaaatac
    78661 caatacatga tagttgcctg ttataattag agaaataaat acgaataata actttataaa
    78721 agaattaaat ggaaaatcga agagttatat tcagtatttt aaaaagaata tgaaatgaga
    78781 aatgaaaata aggtgtttat attaaaagag gttttacaca aaatatttaa aaacgtgata
    78841 aataaaaact gtatttagat agattaacta ttagttttat ataatatgga ttttatttac
    78901 aaagtttaca tattttacaa aagagattaa agataaattt aaatatatat tttatatact
    78961 tgtttatttg tttctctgtg gttgattttt tcgtcaaaag tcaacttcaa atcgcttgtt
    79021 agctttacat gtttaaggat ataattatac ataaggaggg attgacatga atgaattaaa
    79081 catcgcaaaa acgctgattt taaagcgtaa agaaaaagga attacacaag atgaacttgc
    79141 aaattatata ggcgtttcta aagcttctgt atctaaatgg gaaactggac aaagctatcc
    79201 tgacataact tttttaccgc aactcgcgac atatttcaac attaccgttg atgagttaat
    79261 atgttatgaa cctcaaatga tgaaggaaga tattaataaa ctgtataata aactgtgcaa
    79321 agactttacg gttaaaccat ttgatgaagt catggatgaa ataagagaaa tcataaaaaa
    79381 atattattca tgttttcctt tgatttttcg gatgggtctt ttaatagtta atcactatga
    79441 tattgtagat gaaaaaaagc gtgaactatt aattagtgaa gcattagaaa tatttattcg
    79501 tatacaggaa acttgtaatg acatagatat ttgccgtcaa gcaaaaagta tggaggcaac
    79561 ttgttatata ttgttaaatc aacccataca agtgattgat ttattgcaaa acagcaattt
    79621 tcccatgata aatgaatcta tacttcttgc acaggggcaa atgatgaatg gtcaaatgga
    79681 tgaagcgaga gaaacatttc aacttggtgc atatcagaac cttatatcat tagtccaaaa
    79741 cctagtgggt attttgcaaa atgcagataa attacaaatg aaggaaatag aaagacgtat
    79801 tctagcaatt tcagatatat ttgagcttga tacattatct cctgctatta tgctttcttc
    79861 atatttaaca caggcacaaa ttaatttaat acatggtgat aatgaaggag ctattaaatc
    79921 attacgaaaa tatgtagatt tagcaacacg tgatatatac ccaattataa tacatgggga
    79981 tgactttttt aataaacttg acagatggat ttctgaaatt ggaacaggta ttacacgtga
    80041 tgatacaatc gtaaaagcag gtattgttgc tgctattaaa aataatccaa tgttttctgt
    80101 attaagtgaa aacaaagaat acaaatttct tatagaaaaa ttatctttat tggaggaata
    80161 agattatgga aaatttgatg gaatacttac cacttttggt tcctgttatt attttagatt
    80221 taatacttat aattactgca cttgttcatg tattgagaca tccaaattat aaaattggaa
    80281 ataaggcaat atggattatt gtagtactgt ttattagtct aataggacca attttgtatt
    80341 ttacaatagg aagaggtgaa gaatgatgaa tattgtctca ataaatggat tatcaaaagg
    80401 ttttggtaat cgaaagataa tagataattt aaattttact gtaccagaag ggtcagtctt
    80461 tgggtttgta ggtaagaatg gtgcaggtaa gactacaaca atgaaaatgg tacttgggtt
    80521 acttaaacca gatagtggaa ctatagatgt ttgtggtgag aaagtgacct atgggaaaac
    80581 aagttctaat cgtcatgtag gttatctgcc tgatgttcca gagttttaca actatatgag
    80641 accacttgaa tatctttctc tttgtggtga aattacggga ctttcaaaaa aagaaataca
    80701 gataaggagt gaagagttgt tatcacttgt gggtcttgga aatgaaaaga gacgaatagg
    80761 tgggttttct cgtggaatga agcaacgact tggtatagct caagctttgc tttcacgccc
    80821 caaattactt atttgtgatg aaccaacaag tgcacttgac cctgttggtc gaaaagaaat
    80881 attagatatt atgcttaaaa tcaaagactc aacaactgta atattttcaa cacatatact
    80941 atcagatgtt gaaagaatct gtgaccatgt tgctatatta aacaaaggaa gcattgccct
    81001 tagtggtaca ctttcagaaa taaaaagtat gcacggaaag gatagacttt tactggagtt
    81061 tgcaagtaat gatgaaattc aaaagtttaa gtctagtgat ggtattaaat ccttactaaa
    81121 agattcagaa gaaactaata tggaaattgt tttgcatggt aaagatataa aagcaataca
    81181 aaaaacagtt atatctacac tcgcagaaat gaatctttgt ccagtaaaga tggaactaat
    81241 agaattatca cttgaaaatt tatttttgga ggtagtaaag tgagagaata catagcattt
    81301 acaaaaaaag aatttaaaga gaatttaaga aattataaat tatttagttt aattatttta
    81361 tttctaatat ttggtataag tagtcctatt tctgcaaaat ttatgccaga cttgattgct
    81421 cattttgcac cgactttaaa agttactgct gcaccaactg ctttagattc ttggacacaa
    81481 ttttttagca atatctctgg tcttggtatg agtttaactc taattatttt ttgtaatatt
    81541 ttatcaaatg aatattctaa agggacactt gttattatgc tgactaaagg tttatcacgt
    81601 tcatctatag tattgtctaa attctctgtt acggtgatta ttatgacaat tggtttttgg
    81661 ttgagttttt tatttgctta tggctataca atatattttt ggccaactgc aaatcttaat
    81721 catattatat tttcagcatt taatttatgg cttataggaa ttatgtatat tagtgtatta
    81781 attcttgggt gtgtactatt tagaccagca tttgccagtg ttttacttgt attggtggca
    81841 actcttttat tgagtttaat ttctattcct aaacagattg caccttatac tcctaatttc
    81901 ttgatgtcaa aaaatataga cttgatttca gggaaagtgg caatgccaga atttattatt
    81961 ccaattatta taacagttct tatttctgta gtatgtttac tagcagctgt tattttattt
    82021 aataaaaaac cagtttaata atacctttat cacaaggtaa agtaatctta tgttgttaaa
    82081 aactacacct aaaaatcaaa aagacttgga cttaagtttc aagtcttttt gatttttaat
    82141 atatagaatt aagtgtagaa aataatacaa ataatattat ttgtatcaaa taaatataag
    82201 aatatttaat tatgttaaaa tatactaaaa attactttaa aagtgataaa attagtataa
    82261 gtaaatattt taaaggggtg tagatatgga aaagtcaaaa gtatattttt gtgatttata
    82321 ctcaaattcg caaaataaaa acgtaccaaa caatgtaaga agattatttg atgaagcagg
    82381 attcaaagat ttaatagaaa agaatgacca agttgcaatt aaacttcact ttggagaaaa
    82441 gggaaatact acatatatga gtcctgtggc agttagacaa gtggttgata aggttaaaga
    82501 ctgcgaagga aagccatttt taacagatac aaatacactg tatacaggga gtagaacaaa
    82561 ttctgtagac catcttacaa ctgctataga aaatggattt gcttatgcag ttgtaaatgc
    82621 accagtaata attgcagatg gattatatag tagaaattat gagaatgtaa aaatagacaa
    82681 aaaacatttt gaaagtgtaa aaataggtgg agaaatttat aattcttctg caatgatagt
    82741 aatgagtcat tttaaaggtc atgaagcagc aggttttgga ggagcattaa aaaacttagc
    82801 tatgggatgt gcaagtgcag caggaaaaca aatgcaacat tctgatgtta ctccagtagt
    82861 aaaggaaaag aagtgtgtag gttgtggaaa gtgtgttaat tcttgtccta caaaagctat
    82921 aagtatagtg gataaaaaag cagttataga ttctgatgta tgttatggat gtggagaatg
    82981 tccaactgtc tgtccaacta gagcagtaac tatacaatgg gaaagtgact cagatgtgtt
    83041 tgtcgaaaag atggcagaat acgcttatgg agcagtatca aataaaaaag acaaggtagg
    83101 gtatataact tttgttatga atgtaactcc actttgtgat tgtgtacctt ggtcaggtag
    83161 accaattgcc catgatatag gaatattagc atcaacagac cctgtagcta ttgaacaagc
    83221 atgctatgat ttgatttgta aggaaatggg tcatgatgtt ttcaaacatg aacatcctca
    83281 tgtaaatgga actagaataa tagactatgc atgtgaaatg ggtatgggaa gtaaagaata
    83341 tgaattaata aaattataag aatagtagca cttaaatgca tataattatt gtaagagaaa
    83401 tctaaaagta tcaaaggagt atgcatttat gaaaatttac tatgagaagg aaaacagcaa
    83461 gaaggctaat gtaaacaata ttccaagtgt atttgcgttt aattttctaa gaaacttttt
    83521 gactagcaaa gagtatgagg aaactagaaa agaatatttt ataaataatc taacaaaaag
    83581 tcaggttaat caagccatga aggatttaaa atggctattt agagaatatg aaggcttaga
    83641 ggttattaca atggaaagct tggatggagt taagacaagg atagttttat aaaccagtaa
    83701 gaattatatt ctaataaaaa atactgtttt aataataata tgtataatcc atttactaat
    83761 attattttga agcagtattt ttttgtgtat agtaaacttg tgtctaaaat aaagttgacc
    83821 aataaatgtt atatatgcaa tactatatat aataagtaaa ctacataaaa atattaagtt
    83881 gacaaatagg aggatatatg gaaaaataca taataaaatt aaaaaataaa gtattgagag
    83941 aaaaagaaat aagttatgaa gaagctctta atttaataag ccttgataca aataataaaa
    84001 acgattttga tattctatta aaatctgcaa atgaaataag agaatatttt atgggaagaa
    84061 aagcagattt atgtacgata atgaatgcta aatctggcaa atgtagtgaa gactgtaaat
    84121 tttgtgctca atcatctcat tataaaactg gtgtagaaga atattcatta ttagattaca
    84181 atgaaatctt aaatagagct aaagagatgg agagtaaagg agtgcataga ttctcattgg
    84241 ttacaagtgg taaaggtatg tcaggaaagg agtttaataa tattttaaat atctatgaag
    84301 gattgaggga aaatactaat ttaaaattat gtgcatcttt aggtattata gattatgagc
    84361 aagctaaaat gttgaagtca gcaggtgtga ctacatatca ccacaatgtt gagacgtgta
    84421 gagataattt tcataatata tgtacaacac acacatataa agataggata aaaactataa
    84481 aagatgctaa aaaagctggg ctagatgtat gtgtaggtgg tataattgga atgaatgaga
    84541 gtgaagaaca gagactaaaa atggcttttg aaatacgaga attaaatgta aaatcatttc
    84601 caataaacat tttaaatcct attaagaata caccaatgga aaattatgat gtattagaac
    84661 caatggaaat actaaaaaca acagcagtat ttaggtttat aattcctaat gtgtacataa
    84721 ggtatgctgg tggaaggcta tcattaaagg gatatgacaa agttggattt aatgggggag
    84781 taaattctgc aattgttggt gattatttga caactgttgg aagtgggatt gaaaatgata
    84841 aaaaaatgat tatagagcaa ggatttgaac tttaataaat actgcttaaa ttaattaata
    84901 tacttttaga taattataaa agtatattaa tttttttttg cagattaatt taaatattaa
    84961 aattgaatta taagttgcaa tattttgaaa aaagggaaaa atatcaaaat ttatataaaa
    85021 tggttgcaaa tggaaaaaag atgtgatagt atctaggtaa ccggttaagt aaaacggttt
    85081 cctaaatttt gggggtgaac ttcttgagta taactataaa agaaattggc gaattggctg
    85141 gtgtttctaa aacaactgtg tcaaaagtca ttaataataa agatgaaaat ataagtcagg
    85201 caacaagaga aaaaattttg aaaataatga aggaaaaaaa ttatgtacca aataaattag
    85261 cacaaagttt agtaactaaa aaaactaata ctatagggct tcttatacca gatatacgaa
    85321 atccattctt tacagatgta tcaagaggtg tagaagacaa agctaatgaa gaaggttaca
    85381 atataatttt atgtaataca gatgaagatg ctaaaaaaga atatgaagga ataagaacac
    85441 tatcagagag gatgatagat ggaattatat ttgcagcatc ttcaaataca aactggaaag
    85501 aagcaaatta taaagatata aaaataccaa ctgtcttgat tgataagaag ataagtatga
    85561 acaaagaaac cttaaaagga attgttaaaa taaataactt tgaaggggcc tatatagcta
    85621 caaaacattt attagatatt ggaaataaga aaataatata cctaagtggt ccacttcaaa
    85681 atgaaatagc agtagataga ttagaaggat ataaaaaggc tctaatcgag tgtaatttaa
    85741 gctacaatcc tgcttatgta tttgaaggaa aatataagat tgaatgggga caagaattta
    85801 taaaaaattt agaaaagata gattttgatg caatattttg tgcaaatgat ttgattgcaa
    85861 taggtgtcat aagaggtctt aaagaaagag gattaagtat accaaatgat ataagtgtcg
    85921 tgggatttga tgatattcaa acatcaagtc taataagccc ttctcttacc acagtaaaac
    85981 agccgtctta tgatatagga tataaagcca gtgaaatatt gataaattgt ttaagaggag
    86041 ataaaaaaga atcgtttgat gaattgattt tcaaaccaga attggtcata agagattcaa
    86101 caaaagaaag tgaataacag cacgagagac ataaatagat atgtaaagga gtaatgtaat
    86161 gggaaatata gttgtcatag gaagtgtaaa catggacatg gtatgttctg tagataaaag
    86221 accagaaaaa ggagaaacag tattaggtaa tagttttttt acatcacctg gaggaaaagg
    86281 ggctaatcaa gctatctcag cttctaaact aggagcaaat gtaaaaatga tatcatgcat
    86341 aggggaagat ggcttaggag aggagttaat aagaaatttt agaacgaata aagttgatta
    86401 tagcttagta tccagaaata atcacaaaag ttctggtgtt gctgttataa cattatgtga
    86461 aaatgataat agtattgttg ttgtaccagg gactaatgag ctagtagata tagaattaat
    86521 taaaaagaat gaagaagaga taaagaatgc agatatagta ttgctacaat tagagattcc
    86581 attaaaaaca ataaattatg tagtgaattt ctgttttgaa aataggatta gggttttatt
    86641 aaatccagca ccagcagtaa aactaaatga agatataata gaaaaagtaa cttacttaac
    86701 accaaatgaa catgaatata agatagtttt tgacacaaat gaagggatag aagaagtatt
    86761 aaaaaaatat ccaaataaac ttgtaataac agaaggaaaa aatggagcta gattttatga
    86821 tggtgaggaa atcaagcatg tatcttgtat aagtgttgat gttcaagata ccacaggagc
    86881 aggagataca tttaatggag cattggcagt ggctataaca gaagggaaaa atttatatac
    86941 agcagtagaa tatgcagtag tagtatcagg tctttctgta actaaactag gtgcacaatc
    87001 tggtatgccc tataaagaag atgttgaaaa gtatttaaat aataaataaa aatctaattt
    87061 gttcaaattt aaaactatta aaaatggagg ttaattatga gagtgagaaa aattttatct
    87121 ttaggaattg ctggaatact agcaatagga atgttaacag ggtgttcaat ggaaggacca
    87181 agtaaatcag ataataaagg tggttcagac aagaaagatt taactattgg agtatctaca
    87241 ataactcttc aacatcaatt ttttatagat attgatgagg gaataaaaga aaaagctaaa
    87301 gaattaggtg tgaaagttat agtaaatgac ccagaccaag atgtagctaa gcaaacatca
    87361 gcaatagaag attttataca acagaatgta gatggaatga tagtacttgg aactgataat
    87421 tcggctatag taccagcagt agaaggagca tttgaaaaaa tgccagtagt tacagtagat
    87481 gctgtattaa atactgaaaa tattacaagt tatgtaggaa cagttagtta tgatgctggt
    87541 aaaaaattag gggaatacac taaaaaatac atagatgaaa agttaggtgg aaagtcagaa
    87601 atagcaatag tgacagattt aaaatctcaa atacaaatgc agagaataga tggatttaaa
    87661 gatgcattaa aaggttcagc aaatgttaag atattaaatt cacaaccagg atatgacaga
    87721 gaagaatctc ttaatacagt agaaaactta attcaatcta atccagatgt agatataata
    87781 tatgcaacag ctgaaaatag tgtactagga gctaaagctg cacttgaatc tgcaaaaaat
    87841 aaggatgtta agattgtagg atttgactta actgaagaag catcaagtgg aataacagat
    87901 ggaactattc ttgctatgat tcaacaacaa cctaaagaga tgggacgttt agctgtagaa
    87961 gcagtagtaa aagctataaa aggggaaaag gtagaaaaga atataccagt accagcttta
    88021 ctttatgata aggaaaatat aaaagacttt aagaattagt aaaataaaat gagattattt
    88081 gaaagaaatc ctatttaaaa aggagtgtca ttatgagtaa tataattctg aagttaagta
    88141 atattgctaa agaatttcct ggtgtcagag cattagataa tgttaatttt gagttatttc
    88201 atggcgaagt tcatgcacta ctgggtgaaa atggtgctgg taaatcaaca atgataaaga
    88261 ttttaactgg ggcacattcg aaaacttctg gaaaatttat ttttgaaggc aaagaaatag
    88321 agaatatatc cccagatatc tctaaaaaga taggtataaa tgccatatat caagaactaa
    88381 cagtttttga cgaattaaca gtagcacaaa atatttttat gggaaaagaa ataaatggca
    88441 aagtcttaac caatgacaaa aaaatgaatg aagaagctaa aaagattttc gataatatgg
    88501 gaatagatat aaatccaaat agtttagtca aagagcttag tatagctcaa aaacaaatgg
    88561 tagaaatagc aagagtttta tcatcagaaa ctaaagtatt aataatggat gaacctactt
    88621 cttcaataag taaaaaagag actgaaatac tttttagact tataaatgat ttaaaagaga
    88681 gtggagttag tataatatat atatcccata ggatggaaga actctttgag atttgtgaca
    88741 gaataactat aatgcgagat gggaaaacga tttcgacttt aaataccaaa gatgtatcgt
    88801 ctgaggaaga attagttaat ttaatgatag atagaaagct agaccaattt ttcccaaaaa
    88861 gaaaagtaga aataaaagaa gaaattatgc gagtggaaaa tctaactaag aacaatgttt
    88921 ttaatgatat tagctttaat ataagaaaag gtgaaatatt gggaataggt ggactagttg
    88981 gaagtaagag aagtgaaata gtagaagcta tatttggact tagaacatat gattctggaa
    89041 aaatatattt aaacaatgaa gaagtaaagt ttaaaactcc atcagatgca atagaaaatg
    89101 gactaggatt aataacagaa gatagaaaag gtactggatt gtttttacaa atgagtgtca
    89161 aagaaaatac aactatggct gggttaaaaa agatatctaa gtttaaatca attatagata
    89221 gaaaaaagga aaaagagatt ttagaaaaat acatagaagc tttaaagata aaaacaccac
    89281 atatgaatca agttatacaa agtttaagtg gtggaaacca acaaaaagct ataatagcaa
    89341 gatggctttt attacaacca gatatattga ttatggatga accaaccaga ggtatagatg
    89401 taaatgctaa ggcagagata tacaatctaa tgggagattt agtggagagt ggtgtaagta
    89461 taataatgat atcttctgaa ataccagaat taatatcaat gagtgacaga ataatggtta
    89521 tgagagaagg tcatataagt ggatttttag aaggtgaaga aatggttgaa aataatgtat
    89581 taaaattggc tttcggaggt aaaattaatg agttcaataa ctaagcataa agaagaaaaa
    89641 tcttctccat tattgacaaa attaacaagt gtatttagag accaagggag tgcagctgta
    89701 ggacttgtaa taatttttat aataatgagt gtagcttcat ctaacttttt aactttagat
    89761 aatttaatta atgttggaag acaaatatca ataaatgcaa tacttgcagt aggtatgaca
    89821 tttgtaataa ttacaggagg aatagattta agtgtaggag cagtaattgc tttagtaggt
    89881 acattttggg ctacaacagt agtgaattat aatgcaccta tatgggtagg tatgatactt
    89941 gcattagcaa tagggacaat tttaggagtc ataaaaggtg caattatttc aacacaaaaa
    90001 ctacctccat tcattgtaac tttagccatg ttaacgataa taagtggggc aagctttgta
    90061 tttacaggag gaagacctat atcagtaaat acagatgcat ttaagatgct cggtagagga
    90121 tatattggac caataccaat accagttata attatgatta tagttgtaat agcaggacat
    90181 tttctattaa aaagaactaa ttttggacgt catgtacatg cagtaggtgg aaatgaagag
    90241 gccgctagat tatgtggagt aaaagtaaat aaagttatag taaaagtata cgcactagct
    90301 ggactactaa cagcattagc tgggataata ctatcatcac gtttggcatc aggttcacca
    90361 actgttggag atggagcaga attggatgct atagcagccg ttgtgcttgg tggtactaat
    90421 atgatgggtg gttctggttc tatagtaggt acatgtatag gtgtcggaat aataggaata
    90481 ttaggaaatg gattaaactt attaagtgta tcttcatata atcaaatgat tataaaaggt
    90541 ttggtaatgt tatttgctat atggataaat aatataaaat taaaaaaatc agctaaatct
    90601 aaatagtaat taaattttag cttataaact ataaaaatta ttaagttttt gtatatattt
    90661 ttatacttta atttgcatac atctttatac attgaatggg aatatgctaa gtgaaaaagt
    90721 ttactatggc ttaaatagat gagattagac ttgaaatttt aaatgtaaaa ataaatctta
    90781 ggaggaaata tgaaaaaaat tctcttagat acattaaata gtaaaaaaca agaatacata
    90841 gattatttaa aagaacttgt aagtataaag actgaagatg ttggtcatgg aatactaggt
    90901 ggatttgaaa aagaaggaca ggaatatatt gaaaaacttg caaattacat aggttttagt
    90961 gtagatagac aagaaatgag cgaagaatta attaaaaaag caaaaaatat atataaagaa
    91021 ggaaatctag gtcacaatta tcaagataga tataatttaa tttgtaagta tagtgatgat
    91081 ttacctggta agacaattgt atttaatggt catgtagaca ctatgccacc aggtgatata
    91141 agtaagtgga aatataatcc atatcgtgct acagaagata atggaaaact ttatggactt
    91201 ggaactgctg atatgaaatc tggacttata gcatcaatat tagctgtaaa gcttataaaa
    91261 gatagtggtc taaatgtacc tggtaatgta aaaataatgt cagtagtaga tgaagaaggt
    91321 ggcggaaatg gtaccataaa tgcagttatg aatggtattg atggagattg ttgcataatt
    91381 tgtgaaccat cagaacaaaa cttaatagtt gcacatatgg gatttgtatt ctttgaagtt
    91441 gaggttaaag gtgtgtctct tcactgtggt agtaagtggg agggtgtaaa tgcaattgag
    91501 aaggctatgt tgttgcttca agatataaaa gagttggaac ataactggct tatgatatat
    91561 aaacatccac tattaccttc acctacaata aatttaggtg taataaatgg tggaacagca
    91621 ggttctactg tgccagataa gtgtgtattt aatttatgtg tacacttctt gccaaatata
    91681 atgagttatg aacaagttgt aaatgatgta acaaatgtca taatgacaag ggctaatgga
    91741 gatttatggc ttaaagataa taaaccaaat ataaacatat atcaatcagg gttaggtttt
    91801 gagatggaca aggattctga ttttgtagtg aatgcacata aaatactaga agaaactcta
    91861 gggaaaaaat tagagataaa aggttcaaca gctggcaatg atgcgagatt aatgaaaaat
    91921 ttagctgaaa taccaacact tatattaggg ccaggttcaa tagaacaatg tcattcaatt
    91981 gatgaatatg ttgaaattaa ggagtattta gatagtatac ttatgtatgc aagtctaata
    92041 ttaaacttat aaaagtagga ggaatatata aatgaaaaaa gtattaatag taggggaatc
    92101 ttgggtaaaa aatataactc atataaaagg atttgatacg tttgttacaa ctcattatga
    92161 agaagctgta aagtggttga aagaagcaat agaatctgga ggatatgaga cagttcatat
    92221 gcctgcacat gtagcagcag atagttttcc gtataaatta gaagagttaa atgagtatga
    92281 ctgtataata ttatctgata taggttctaa tacgttctta ttatctaata gtacttttat
    92341 agattgcaat agtaatccag atagacttga actaatcaaa gagtatgtaa ataatggtgg
    92401 ggcgttaatc atggtaggtg gatatatgtc atttacagga atagatgcaa aagctagatt
    92461 cggagaaact gctatcaaag atgtattacc aataacaatg atagataaag atgatagagt
    92521 tgaaaaacca gcaggaataa ttccagaagt tattgactct aaacatccag tattaaaagg
    92581 tataccaaca gaatggccaa agtttttagg atataacaaa acagtagcta gagataattg
    92641 tcctgtttta gcaactattg gaggagaccc atttgtagct gttggcgagt ttggaaaagg
    92701 aaaatctgct atctttagtt ctgactgtgc acctcactgg ggtccaaaag aatttactga
    92761 ttggaaatac tataataaat tatgggttaa tatgcttgat tggttaacat gctaaaaatt
    92821 ttataaaact tgaaaacctc ttacttgata aaatgaaact tacaagtcaa gaggttttat
    92881 tgtataaaat ggttgtatga tagaaaatat ttttaaatca gttaaaatta gtcattttgg
    92941 ctgataatcg ataagttatt agaaacaggg aggtttatat aattaatatg gagaatttaa
    93001 ataaaaagtt tttgatggaa tatatagatg agatacaggg agaattaaga gatatatcag
    93061 ataagatatg gaaaaatcca gaacttcagt ataaagaata ttatgcttca aatttacaaa
    93121 aagaatactt aaaaaaatat ggttttagta tagatgaatt agaaggtatg gatacagcat
    93181 ttgcggctag ctatggagaa ggtagaccag ttatagcagt tttgggagaa tatgatgctt
    93241 tagatagttt gtctcaaaaa gtatccacta ttaaagaacc tattgtagat ggtggtgcag
    93301 gtcatggatg tggacataac ttactgggta caggttcaat aggagctgta attgcagtaa
    93361 aggaattaat caaactaaaa aagctgaaag ggactataaa atactatgga tgtccagcag
    93421 aggaagattt atctggaaaa gtattgatga taaaaaaagg tttttttgat ggaattgatt
    93481 gtgcttttag ttggcatcca tttgatataa atactcctat aagaatccca acacttgcta
    93541 attactctgt gaaatttaga tataatggga ttagtgccca tgcagcacaa gctccttata
    93601 acggaagaag tgcacttgat gcagtagaac ttatgaatat aggttgtaat tatttgagag
    93661 aacatatatt tgataattgt agagtacact atgtaactac taatggtgga aaaatgccaa
    93721 atatagttcc tgattttgca gaagtgtggt attacataag aggagttaaa atggagcatg
    93781 taagagatgt atttggtagg attgttgata tagcaaaagg agcagcatta atgactggta
    93841 ctattatgga atatgacatt ataagtggag tatatgacta tattccaaat acaatattaa
    93901 cagatattct atcacaaaat atgaaattag taggtgtaca aaactataat gaagatgact
    93961 actattttgc agataaatta gctgagacag tgtctataga taaaagaagt agtgtttcta
    94021 gtgtattaag tggaaataag gatattacta agatgaatct gcatgatgaa gttacggatg
    94081 atacatttac tcataataac tgtatatcat tatcattgga tattggagat gttagttaca
    94141 taattcctac agcacagtgt tcttgttcag tttggcctat tggtatttct gcccatacat
    94201 ggcaatcttg tgccagtgca ggttctgata tgggatttaa agcaatgtta ttggcatcta
    94261 aatctatatc atgttcaata aatgatgtaa tgcttgatga attggttata aataaagcaa
    94321 aaaaagaatt gaaggatact gtaggtagtt ttaaatatat accaattatt taaaacttaa
    94381 attgatataa gcacaactaa cttgtatgag ttaatataag tatataattt aatattattt
    94441 ttaacccaac cttctaatta ttttaaattt aagatacaat gattagaagg aattttttaa
    94501 gtttcttaga atactgtaaa ttatataatc ttgataaaaa gtgttatact atatataatc
    94561 taaataaaaa atagtacaaa aaggagtatt tatgtttgga tatgttaaaa taaacaaaat
    94621 ggatttaaca tttagagaat acgattatta caaagcttac tattgtggac tatgtaaata
    94681 tttaaaaaga aatcatggag aaatctctag gttttctttg aattatgata taacattttt
    94741 aattgtttta ttaacagcag tatataaccc agagtctata agtacagagg aagtgtgtat
    94801 agtaaatcca tttaaaaaga aaaaggtaat tacaaatgat attacagaat atgcagcaag
    94861 tatgaatatt cttttaacgt attataaatt ggaagataat ttaatggatg ataaacgcat
    94921 aaaagataaa ttggcatatt atatatataa aaacaaatta aaattagcat atgaaaagta
    94981 tcctgaaaaa gcagagtata taaaacaaca actaaatgaa ttaaataagt tagaaaaaga
    95041 taaaaatata aatatagatg aagtatctag tatatttgga aatataatgg gtgaagtatt
    95101 tgtctataaa aaagatgaaa atgagagaaa cttaagaatg ataggtttta atataggtaa
    95161 gtatatatat ctactagatg cctatgaaga tttagatgaa gattttaaga aaggaagata
    95221 taatccattt atagagtata ttgataaaaa tgatgagtta aaagaaaaag taaaaaaaat
    95281 aatagtaaca tcattagggt ttttagctag gggaattgat aatctaaatc taaataaaaa
    95341 tgttggaata atagaaaata taatttattc tggtgtttat ttaagatata ttaatatatt
    95401 agaaagtaga ggtggaaaga atgtacagta atacttataa taatgaaaat tttatgagag
    95461 caagagcatt catagaaaat agtgaattta aaaaagcata tgatttttta aaaactttga
    95521 ctgacaaatg tgcagagtgg tattatttaa ctggcttttc tgcaatgaac ataggatatt
    95581 atgaagaagg tgaagacttc ttaaaaagag caaaatttat ggagcctgaa aatagtgaat
    95641 atagtgatgc acttagaagt tatacacaat atagaaatga ttatagcaat agggctgaca
    95701 attataatag aagaagacgt aatgatttag atggatgttg ttgctgttgc tgtgatgatt
    95761 gctgttgttg tctaggtgac gattgttgtg aaaattgtgc taagctttgg tgtttagatt
    95821 catgttgtga atgttttggt ggagatttaa taacttgttg ttaggatgat aaatatgagt
    95881 ataaaagttg cttatggagg agttttatta gcattaaatg tgatattgtt gactcttaca
    95941 aatattattc ctgtaaatac attgtttatt atggggttag catcactttt agtatcaatt
    96001 gtaataatgg aatggggctt taagagtgga attgcttttt atataggttc tatagtttta
    96061 ggatttatag tgatggcaag taagtctcaa tggattgtat attcacttac ctttggaata
    96121 tatggtattg taaaatatct tatagaaaaa gataggtcta tatatattga gtattttatg
    96181 aaattagtat ttgcaaatat aatgatactt atattgtatt ttttattaag aacaatagtt
    96241 tatattccaa taaacatatt tattataggt tcatttgaga tagcctttat agtatatgac
    96301 tatgtttaca gttcttttat aggttattac aataatagat taagaaagat gctatttaaa
    96361 aaataatagt tgatttttat atttaatttt aatgaaattg tagtttagat aagtgtaaat
    96421 gatatatatg aatatacatt aaagcataaa gctaaattta atatattctc ttagtgcaac
    96481 atataaaagc tttgattttt agtcaaagct tttatatgtt agatataaat attagatata
    96541 atataagttt ttaaaataga tagtataaat taaatatcca ctatatttac atctgtagat
    96601 agagaataaa taatatcttt tctttctact attatctcaa catttttaga aatttcctca
    96661 tcaagtgata tttgagataa aagttccttt gttggattta ttgctattgg atttccaact
    96721 ctttttagca tatttatatc accattagta tctccatagg catacgagtt tgataaatct
    96781 aaatcatact ttacaacaaa atcgtttata gcattattct tacttataga atcccacatt
    96841 ggaataactg tgcctgtaaa tatattgttt tcaaagacat aatcacttcc taaaaaatcg
    96901 gttacattat attttttggc cattttttca acaagaaatc cagggctacc agatataaat
    96961 ataactatgt gtccttgatt tagatgccac tcaatccttg aacgtgtgta tttataaact
    97021 ctatctgctt ttaatttaat tacttggtca cttgtaaagt tgatacaggt tttatctaat
    97081 ccttttagtg aatcaacata aaggtcacat atttctaata gataatcatc ataattacct
    97141 tgtcttttat cccaatccat aaaagtgtct ctagcatgtt tataccaatt tttttggtca
    97201 attatatcgt atttaattaa ttttttaaaa tgttcaacca taagagagtc tctataaaga
    97261 gtaccatcta tatcaaaaaa agctgctata tttttcataa gaccacctca attaatcatt
    97321 tccttatatt atattataaa ttgtatctaa gttgttaaaa tatatgtata ataatttata
    97381 tattaaaaaa caagtatttt agagtttaaa ggatgtgact atatgaattt taattttgca
    97441 aaggctacaa attctagact tatgggcagt ttaggtctta taataaattg gatagatgat
    97501 gaaaacaatc acttttgtca atatttttta ttagatgcag agggattagg attagcggat
    97561 tatgtgagtt taaataaccc aacacaagaa gaagcttata tggaagaaga aagattgatg
    97621 ggaggatttg gttcagatag agttgaatta acgaaggatg aatctttatt tttagtatct
    97681 tattttggta ataagaatct ttattatgat aagctattgc caggagataa atgtgagtat
    97741 attgatatta taaaaaacta taaaacagat ttaactatag aaaaattata caataaaata
    97801 tgtaaaagag ttgacgagga agttgaattt ataaactata tgaccatgag atttatagca
    97861 tgggatagag aaagtttaaa gtacttttct ggaagtgacg agattgcaaa tatgcacatt
    97921 actaatataa atggaacatt acttaaaaac gtggtaagtg ataaaggtca aggcagatat
    97981 ataagtgaag ctttatatga agataatgat ggatattata tatgtaaaat tgctttttgc
    98041 ataagtaagt gttatgaaac tggttttaga attaattctc tattagtgac agataaagaa
    98101 cctatgtatg attttgaggt atttgatgag atttctaaaa gtgaatttgt aagtgtttac
    98161 agtgtaaatt cacctgaaga atttgcagga gtattttata gagaaaatcc atttctgtta
    98221 aaaagtaata tgaatgaagg tatattcttt actagattta attttaataa tgaccatgta
    98281 aaagaaaatg tatatataat aaataatgat atgaaagcta tatattactt aatgggaaat
    98341 aagtttttta ttggtactta taacgaaaat gattgcaatt atatcaatga aataagtcaa
    98401 tctaattata gcgactatat taaatttgaa gagaaatttt tctttgagca aaatgcatta
    98461 tatgattttg cagaatcagg ttcattagat tttgatgatt ttttggaata ataaatttag
    98521 acattattta agcgagatta actgaattta atctcgctta aatttatttc tataatattg
    98581 ggggaatatt atgaggaata catttattat tgtggtcaat tattaaaatt ttatacagtt
    98641 tattataaaa aatttatatt tttctttatg ttgtttgcca atattagtct caaatacgag
    98701 tatcatacta ttctgaccca ccaatacaag agagcatttt taaatgaaaa agtcagataa
    98761 aattaaattt tatctgactt tttctatgtt tatcttatta gattatgtta atatctgttg
    98821 accgaataag cgcatattca gtcaactttc tatacctata ataatattgg gggaatatta
    98881 tgaggaatac atttattatt atggtcaatt attaatgttt tatacaactt acttaaaaaa
    98941 atatatatta catttcttcc tcatcaaatt cctcaatatt agtagcctgt ggtatacctt
    99001 gtatagacat attactagaa ccataaggag taggatatat attaggaggc atagtactag
    99061 gcataactac aggcatacct tgcattgtat tatgacatat aactcctggt atcatcataa
    99121 gtacattagg aggcatattt tgattacatg agaagttagg aatacccata gtattgttca
    99181 tattataccc catattactg ttcatgttat taggcatacc tgtattacca tacatattgt
    99241 tattcatatt gccagacata ttgttaggca tacccatatt actattcata ttattagaca
    99301 tattgttagg catacccata ttactattca tgttattagg aacattgtta ggaatgccca
    99361 tgttactatt catattatta ggcatattgt taggcatacc catattacta ttcatgttat
    99421 taggcatatt gttaggcata cccatattac tattcatatt gttagacata ttattaggca
    99481 tacccgtatt attattcatg ttattaggca tattatttgt agcagatgta ttgtaattca
    99541 tatttccgga tgtattattt gtgttaggca agttgtttgg agaattacta cttttaggat
    99601 aatgatttac attattagga tataggttat ttatgttctg gttattaggt atttttgtat
    99661 aaccattaga aatttgaggg tcatttctca attcatcttg gggaatttct tcattagtaa
    99721 tataatctgc atagttcgct gggtctaagt aaggcatgta actagtatct aaatcctttt
    99781 ttttcttgtt actcatatta aacttgcacc tcctagaaaa ctataaaaaa gtttacaaaa
    99841 acttattcta ataatatata tattaaaaaa gtttataata tgtgcattct atttatatta
    99901 aattaataaa aattattgtt gcaaatttag aaatgataac atataatgaa catatgaaca
    99961 gttattcata tattaaaata atggaggatt aaaaatgaga gaagagataa atgattgtaa
   100021 ttgtaatata gtacatgaag aaatagtaac agaggctaaa tcaactatgc cagatgaaga
   100081 aatgttatat gatttagcag aattatttaa agtatttggg gatactacta gagtaaagat
   100141 attatatgca ttatttgcaa atgaaatgtg tgtatgtgat atagcgagtt tattaaatat
   100201 gactcattct gcaatatctc atcaacttag agtattaaag caggctagat tagtaaagtt
   100261 tagaagagaa ggaaaaacag tgtattactc attagatgat agtcatataa gtcagatatt
   100321 tgattgtgga ttaaatcata ttagagagac ttataaatga taaatgagag gagtgaatat
   100381 atatggaagc aaataattca attaaaaaag aatttatact aggaggatta aattgtgctc
   100441 actgtgcaga ggagattaat aataaagttt ctaaactaca agaagttaaa tcttccaatt
   100501 taaattttat aaataaaaaa cttacagtaa atataaagga aagttttaat gaggatacta
   100561 ctatagaaaa gataatagat ataatagatt caacagagcc aggtcttgat atacaaataa
   100621 gttctaaaga aaatgcagct agtaaaacat caattaaaaa agagcttata ttaggaggat
   100681 taaactgtgc tcattgtgca gaagagatta ataacaaagt ttctaaatta aaagaagttg
   100741 aatcttctaa tttaaacttt gtaaataaaa aacttacagt aaatataagt aataactttg
   100801 aagaggatga tgttataaat aaaataaaag aaataataaa ttcaacagag ccagggcttg
   100861 atatacaagt agggtctact gacaaagtaa aagggagaac tactgaaaaa tcaggagctg
   100921 taaatgatac aaataagaaa gaattaattc cacttataat tggagcactt gtatatatat
   100981 ttggtatata tcaaacagct acaggttatg aaagtcagtt tagcaatata gtatttatag
   101041 ttgcctatgt aatagtaggt ggtgatgtgc ttttaagagc aataagaaat atatcaaaag
   101101 gaagagtatt tgatgagaac tttttgatgg ctctagcaac agtaggagca ttagcaatag
   101161 gggagttatc agaagcagta ggggttatgc ttttctataa agtaggagag tatttacaag
   101221 gtgttgcagt tggtaaatcc agaaagtcta taacttcact tatgcaaata agaccagact
   101281 atgcaaatct aaaagttaat tctgaagtta aggtggtgtc accagaagag gtaaatgtag
   101341 gtgatataat agtagtaaaa cctggtgaaa aagtaccatt agatggtgta gtagtagatg
   101401 gagtttctat gttagatact tctgcactca caggagagtc agtgctgaga gaagttgaaa
   101461 aaggagatga aatcttatca ggtgttataa ataaaaatgc tttattgagt attgaagtta
   101521 caaagagttt tggagaatca acagtttcta agattcttga ccttgttgaa aattcgagca
   101581 ttaaaaaatc aaagacagaa aactttatat ctaagttttc aagatactat actccaatag
   101641 tagtaatagc tgctttatta atagcatttg tgccaccact tgtaatctca ggtgaggtat
   101701 ttagtgattg gttatataga ggattgatat tcttagtcgt ttcttgccct tgtgcattag
   101761 ttttatcaat accacttagt ttctttagtg gaattgggtt tgcatctaaa aatggtatcc
   101821 ttattaaagg aagtaactat ttagaagctt taagaagtgt agatacagta gtatttgata
   101881 aaacaggaac acttactaaa ggtgtgttca atgtaactaa gttaaatcct gaaggtatat
   101941 cagaagaaga attattagaa tatgcagcta ttgcggaggt aaattcaaat catccaatag
   102001 caaagtccat attaagttac tataataaaa aaattgattt agatacaata gacagttatg
   102061 aggaaatagc agcttatgga attagagtaa agcataatgg caattttata ttagcaggta
   102121 atgagaaact tatgaaaaaa gaaaatatat cttattcatc agctaaagaa gtaggcacag
   102181 tagtctatat tgctgttgat aaagcatata gaggttatat agttatctct gatgaagtaa
   102241 aagaagatag taaaaatgcc ataagaagct taaaagaaat aggggtaaaa gaagttgtaa
   102301 tgttaactgg agataatgag aaagtagcaa aaaatattgc tcaagaatta gaattggata
   102361 cagtttactc aaatttactt cctaatgaaa aggtagatag attagaagat ttatatgaag
   102421 gaagaactga aaaagagaaa atagcatttg taggtgatgg aataaatgat gctccagtat
   102481 tagctcgtgc tgatgttggt atagctatgg gaggcttagg ttcagatgct gctattgaag
   102541 ctgcagatgt agtgcttatg acagatgagc ctagcaagat atctaaagca attgaaatag
   102601 caaacaagac taataagata gtgtggcaaa acataatatt tgctctagga gtaaaaatta
   102661 tagttatgat actaggtgct ggaggagtag ctactatgtg ggaagctata tttgctgatg
   102721 taggtgtggc acttatagca gtagtaaatg ctatgagagc tatgagataa gggataaatg
   102781 taaatccata ctatttaaaa aacttataat tatatattga agtatgtaat aatgaaaggt
   102841 atcaataagt ttcttttaac tttattggta cctttttatt ggagcgcttt gcatatataa
   102901 atttatattc attatccatt atgtttattt aatgtattta tttagtgtag agcttttata
   102961 ttgtaatttt aaaatttaga catagaaggt ttattaataa gtttatatta agtttaaatt
   103021 agattcataa aaattataat acttatgatt gtatatatat tatattaata gttgtaattt
   103081 ttacaacaaa atgtgtgtgt taaaatactc taaaccaaca gtatgactgc cattcaataa
   103141 attatgtaat ataagaaagt aaatattttt aaaaaataat ttaaaaaagt attgacgaat
   103201 tatttttaag
//
LOCUS       DAEHWO010000005        95721 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEHWO010000005 DAEHWO010000000
VERSION     DAEHWO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 95721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95721
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.005"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            229..1446
                     /locus_tag="KNP54_000507"
     CDS             229..1446
                     /locus_tag="KNP54_000507"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBF0891437.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1541..1921
                     /locus_tag="KNP54_000508"
     CDS             1541..1921
                     /locus_tag="KNP54_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBF0891438.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2205..2687
                     /locus_tag="KNP54_000509"
     CDS             2205..2687
                     /locus_tag="KNP54_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0891439.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2708..3523
                     /locus_tag="KNP54_000510"
     CDS             2708..3523
                     /locus_tag="KNP54_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0891440.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3574..5124
                     /locus_tag="KNP54_000511"
     CDS             3574..5124
                     /locus_tag="KNP54_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBF0891441.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPFLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5221..6573
                     /locus_tag="KNP54_000512"
     CDS             5221..6573
                     /locus_tag="KNP54_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBF0891442.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6704..7462
                     /locus_tag="KNP54_000513"
     CDS             6704..7462
                     /locus_tag="KNP54_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891443.1"
                     /translation="MNIINKIFWEEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7509..8228
                     /locus_tag="KNP54_000514"
     CDS             7509..8228
                     /locus_tag="KNP54_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBF0891444.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8352..9752)
                     /locus_tag="KNP54_000515"
     CDS             complement(8352..9752)
                     /locus_tag="KNP54_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBF0891445.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9756..10664)
                     /locus_tag="KNP54_000516"
     CDS             complement(9756..10664)
                     /locus_tag="KNP54_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0891446.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10925..11572
                     /locus_tag="KNP54_000517"
     CDS             10925..11572
                     /locus_tag="KNP54_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBF0891447.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11897..14536
                     /locus_tag="KNP54_000518"
     CDS             11897..14536
                     /locus_tag="KNP54_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBF0891448.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHIEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMNTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14594..15697)
                     /locus_tag="KNP54_000519"
     CDS             complement(14594..15697)
                     /locus_tag="KNP54_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBF0891449.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVREAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16057..16878
                     /locus_tag="KNP54_000520"
     CDS             16057..16878
                     /locus_tag="KNP54_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBF0891450.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16957..17168
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17255..18571
                     /gene="argH"
                     /locus_tag="KNP54_000521"
     CDS             17255..18571
                     /gene="argH"
                     /locus_tag="KNP54_000521"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBF0891451.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELQKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18820..19158
                     /locus_tag="KNP54_000522"
     CDS             18820..19158
                     /locus_tag="KNP54_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBF0891452.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGKP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19285..20574)
                     /locus_tag="KNP54_000523"
     CDS             complement(19285..20574)
                     /locus_tag="KNP54_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBF0891453.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20654..21358
                     /locus_tag="KNP54_000524"
     CDS             20654..21358
                     /locus_tag="KNP54_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBF0891454.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKLNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21450..22496
                     /gene="selD"
                     /locus_tag="KNP54_000525"
     CDS             21450..22496
                     /gene="selD"
                     /locus_tag="KNP54_000525"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21498..21500,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBF0891455.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22514..23926
                     /locus_tag="KNP54_000526"
     CDS             22514..23926
                     /locus_tag="KNP54_000526"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBF0891456.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            24040..25923
                     /gene="selB"
                     /locus_tag="KNP54_000527"
     CDS             24040..25923
                     /gene="selB"
                     /locus_tag="KNP54_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBF0891457.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26028..28766
                     /locus_tag="KNP54_000528"
     CDS             26028..28766
                     /locus_tag="KNP54_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBF0891458.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEHELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28885..29829)
                     /gene="manA"
                     /locus_tag="KNP54_000529"
     CDS             complement(28885..29829)
                     /gene="manA"
                     /locus_tag="KNP54_000529"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBF0891459.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            30002..31363
                     /locus_tag="KNP54_000530"
     CDS             30002..31363
                     /locus_tag="KNP54_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0891460.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31451..33340
                     /locus_tag="KNP54_000531"
     CDS             31451..33340
                     /locus_tag="KNP54_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0891461.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKANTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33355..33810
                     /locus_tag="KNP54_000532"
     CDS             33355..33810
                     /locus_tag="KNP54_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0891462.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33869..34186
                     /locus_tag="KNP54_000533"
     CDS             33869..34186
                     /locus_tag="KNP54_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBF0891463.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34211..35473
                     /locus_tag="KNP54_000534"
     CDS             34211..35473
                     /locus_tag="KNP54_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBF0891464.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35578..36642
                     /locus_tag="KNP54_000535"
     CDS             35578..36642
                     /locus_tag="KNP54_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBF0891465.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YAGNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36696..37874
                     /locus_tag="KNP54_000536"
     CDS             36696..37874
                     /locus_tag="KNP54_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBF0891466.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38065..39123)
                     /locus_tag="KNP54_000537"
     CDS             complement(38065..39123)
                     /locus_tag="KNP54_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBF0891467.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKNGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39190..39561
                     /locus_tag="KNP54_000538"
     CDS             39190..39561
                     /locus_tag="KNP54_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBF0891468.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39598..40272
                     /locus_tag="KNP54_000539"
     CDS             39598..40272
                     /locus_tag="KNP54_000539"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBF0891469.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40521..41360
                     /locus_tag="KNP54_000540"
     CDS             40521..41360
                     /locus_tag="KNP54_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBF0891470.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41604..41700
                     /locus_tag="KNP54_000541"
     tRNA            41604..41700
                     /locus_tag="KNP54_000541"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41638..41640,aa:Sec,seq:tca)
     gene            41850..42557
                     /locus_tag="KNP54_000542"
     CDS             41850..42557
                     /locus_tag="KNP54_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBF0891471.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42699..43535)
                     /locus_tag="KNP54_000543"
     CDS             complement(42699..43535)
                     /locus_tag="KNP54_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0891472.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43723..44628
                     /locus_tag="KNP54_000544"
     CDS             43723..44628
                     /locus_tag="KNP54_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBF0891473.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44637..45821
                     /locus_tag="KNP54_000545"
     CDS             44637..45821
                     /locus_tag="KNP54_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0891474.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            45936..47237
                     /locus_tag="KNP54_000546"
     CDS             45936..47237
                     /locus_tag="KNP54_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBF0891475.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47191..48234
                     /gene="holA"
                     /locus_tag="KNP54_000547"
     CDS             47191..48234
                     /gene="holA"
                     /locus_tag="KNP54_000547"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBF0891476.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48421..48687)
                     /gene="rpsT"
                     /locus_tag="KNP54_000548"
     CDS             complement(48421..48687)
                     /gene="rpsT"
                     /locus_tag="KNP54_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBF0891477.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            49132..50808
                     /locus_tag="KNP54_000549"
     CDS             49132..50808
                     /locus_tag="KNP54_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBF0891478.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            50820..52028
                     /locus_tag="KNP54_000550"
     CDS             50820..52028
                     /locus_tag="KNP54_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBF0891479.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            52043..53755
                     /locus_tag="KNP54_000551"
     CDS             52043..53755
                     /locus_tag="KNP54_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBF0891480.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            53748..54656
                     /gene="pilO"
                     /locus_tag="KNP54_000552"
     CDS             53748..54656
                     /gene="pilO"
                     /locus_tag="KNP54_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBF0891481.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            54683..55249
                     /locus_tag="KNP54_000553"
     CDS             54683..55249
                     /locus_tag="KNP54_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBF0891482.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            55286..55813
                     /locus_tag="KNP54_000554"
     CDS             55286..55813
                     /locus_tag="KNP54_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBF0891483.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            55834..57372
                     /locus_tag="KNP54_000555"
     CDS             55834..57372
                     /locus_tag="KNP54_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891484.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRDISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLYMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLEKLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            57472..58554
                     /locus_tag="KNP54_000556"
     CDS             57472..58554
                     /locus_tag="KNP54_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBF0891485.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            58535..59317
                     /locus_tag="KNP54_000557"
     CDS             58535..59317
                     /locus_tag="KNP54_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBF0891486.1"
                     /translation="MDIIIVNLYVFMVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            59419..60069
                     /locus_tag="KNP54_000558"
     CDS             59419..60069
                     /locus_tag="KNP54_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBF0891487.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            60083..60643
                     /locus_tag="KNP54_000559"
     CDS             60083..60643
                     /locus_tag="KNP54_000559"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBF0891488.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            60660..64046
                     /gene="mfd"
                     /locus_tag="KNP54_000560"
     CDS             60660..64046
                     /gene="mfd"
                     /locus_tag="KNP54_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBF0891489.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            64077..65072
                     /locus_tag="KNP54_000561"
     CDS             64077..65072
                     /locus_tag="KNP54_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBF0891490.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            65196..65735
                     /gene="spoVT"
                     /locus_tag="KNP54_000562"
     CDS             65196..65735
                     /gene="spoVT"
                     /locus_tag="KNP54_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBF0891491.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            65855..67468
                     /locus_tag="KNP54_000563"
     CDS             65855..67468
                     /locus_tag="KNP54_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBF0891492.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            67575..69023
                     /gene="mazG"
                     /locus_tag="KNP54_000564"
     CDS             67575..69023
                     /gene="mazG"
                     /locus_tag="KNP54_000564"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBF0891493.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            69112..69390
                     /locus_tag="KNP54_000565"
     CDS             69112..69390
                     /locus_tag="KNP54_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBF0891494.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            69462..69704
                     /locus_tag="KNP54_000566"
     CDS             69462..69704
                     /locus_tag="KNP54_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBF0891495.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            69766..70020
                     /locus_tag="KNP54_000567"
     CDS             69766..70020
                     /locus_tag="KNP54_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBF0891496.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            70021..70554
                     /locus_tag="KNP54_000568"
     CDS             70021..70554
                     /locus_tag="KNP54_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891497.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            70560..70844
                     /locus_tag="KNP54_000569"
     CDS             70560..70844
                     /locus_tag="KNP54_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBF0891498.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            70957..71877
                     /locus_tag="KNP54_000570"
     CDS             70957..71877
                     /locus_tag="KNP54_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBF0891499.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDKGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            71967..74339
                     /gene="spoIIE"
                     /locus_tag="KNP54_000571"
     CDS             71967..74339
                     /gene="spoIIE"
                     /locus_tag="KNP54_000571"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBF0891500.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            74690..76582
                     /gene="pepF"
                     /locus_tag="KNP54_000572"
     CDS             74690..76582
                     /gene="pepF"
                     /locus_tag="KNP54_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBF0891501.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            76696..77661
                     /gene="galU"
                     /locus_tag="KNP54_000573"
     CDS             76696..77661
                     /gene="galU"
                     /locus_tag="KNP54_000573"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBF0891502.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            78161..79765
                     /gene="rho"
                     /locus_tag="KNP54_000574"
     CDS             78161..79765
                     /gene="rho"
                     /locus_tag="KNP54_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBF0891503.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            79918..80118
                     /gene="rpmE"
                     /locus_tag="KNP54_000575"
     CDS             79918..80118
                     /gene="rpmE"
                     /locus_tag="KNP54_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBF0891504.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            80263..81156
                     /locus_tag="KNP54_000576"
     CDS             80263..81156
                     /locus_tag="KNP54_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBF0891505.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            81174..82022
                     /gene="prmC"
                     /locus_tag="KNP54_000577"
     CDS             81174..82022
                     /gene="prmC"
                     /locus_tag="KNP54_000577"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBF0891506.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            82066..83130
                     /gene="prfA"
                     /locus_tag="KNP54_000578"
     CDS             82066..83130
                     /gene="prfA"
                     /locus_tag="KNP54_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBF0891507.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            83259..83939
                     /locus_tag="KNP54_000579"
     CDS             83259..83939
                     /locus_tag="KNP54_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBF0891508.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            83968..85008
                     /locus_tag="KNP54_000580"
     CDS             83968..85008
                     /locus_tag="KNP54_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBF0891509.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            85025..85474
                     /locus_tag="KNP54_000581"
     CDS             85025..85474
                     /locus_tag="KNP54_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBF0891510.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            85491..85943
                     /gene="rpiB"
                     /locus_tag="KNP54_000582"
     CDS             85491..85943
                     /gene="rpiB"
                     /locus_tag="KNP54_000582"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBF0891511.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            85979..86608
                     /gene="upp"
                     /locus_tag="KNP54_000583"
     CDS             85979..86608
                     /gene="upp"
                     /locus_tag="KNP54_000583"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBF0891512.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            86903..87718
                     /locus_tag="KNP54_000584"
     CDS             86903..87718
                     /locus_tag="KNP54_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBF0891513.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            87944..88381
                     /locus_tag="KNP54_000585"
     CDS             87944..88381
                     /locus_tag="KNP54_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBF0891514.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            88566..88793
                     /locus_tag="KNP54_000586"
     CDS             88566..88793
                     /locus_tag="KNP54_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBF0891515.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            88798..89184
                     /locus_tag="KNP54_000587"
     CDS             88798..89184
                     /locus_tag="KNP54_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBF0891516.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            89187..89891
                     /gene="atpB"
                     /locus_tag="KNP54_000588"
     CDS             89187..89891
                     /gene="atpB"
                     /locus_tag="KNP54_000588"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBF0891517.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            89960..90220
                     /gene="atpE"
                     /locus_tag="KNP54_000589"
     CDS             89960..90220
                     /gene="atpE"
                     /locus_tag="KNP54_000589"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBF0891518.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            90343..90840
                     /gene="atpF"
                     /locus_tag="KNP54_000590"
     CDS             90343..90840
                     /gene="atpF"
                     /locus_tag="KNP54_000590"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBF0891519.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            90837..91382
                     /locus_tag="KNP54_000591"
     CDS             90837..91382
                     /locus_tag="KNP54_000591"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBF0891520.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            91399..92901
                     /locus_tag="KNP54_000592"
     CDS             91399..92901
                     /locus_tag="KNP54_000592"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBF0891521.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            92929..93807
                     /gene="atpG"
                     /locus_tag="KNP54_000593"
     CDS             92929..93807
                     /gene="atpG"
                     /locus_tag="KNP54_000593"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBF0891522.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            93820..95214
                     /gene="atpD"
                     /locus_tag="KNP54_000594"
     CDS             93820..95214
                     /gene="atpD"
                     /locus_tag="KNP54_000594"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBF0891523.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            95217..95477
                     /gene="atpC"
                     /locus_tag="KNP54_000595"
     CDS             95217..95477
                     /gene="atpC"
                     /locus_tag="KNP54_000595"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBF0891524.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
BASE COUNT        38132 a        10285 c        17094 g        30210 t
ORIGIN      
        1 atattattgc tttaataaga atgtaaaaaa tatttttaaa ttatcattta atgtaattta
       61 aatgaattga agatatatgt ttattgtatg caattgttgt atttttaggt tttttgtgat
      121 taattaaaaa attataaaaa tcgtttacat gttgattttt aaaaaaaaaa gatatagaat
      181 tatatagaaa gtaataaaca aaaattggat ttacgggagt ggaatgaaat gatgaatgtt
      241 accttaacag atgtgaaaga ggctagagag accattaaga acatagtaaa aagaactgac
      301 ttacttgaaa gtgttaaact tagcgaaaaa acaggagcaa atgtgttcta taaatgtgag
      361 aatcttcaaa aaacaggttc ttttaaatta agaggagctt gtaacaaaat agcgagttta
      421 acagatgaag aaaaggcaaa tggagttata gcttcaagtg cagggaatca tgctcaagga
      481 gttgcattgg gagcaaaaat gactggtata aaatctacaa tagtaatgcc agcaactgcg
      541 cctttagcaa aagttagtgc aactaaaggt tatggagcag aagtagtttt aaatggtgcg
      601 gtttatgatg atgcatatgc aaaagctgtt gaaatacaaa aagaaacagg agcaactttc
      661 ttacatccat tcaatgataa gtatgttata gcaggacaag gaactatatc tcttgaaatt
      721 ttcgaacaat tagacaataa agttgatact atactatgcc cagttggtgg aggaggaatc
      781 atctctggtg ttgctgttgc agcaaaagca ttaaatccta atgtaaaaat agtcggtgtt
      841 caaactgcaa atataccttc aatgaaagag tcaataaaaa atggaaaagt aacaacagca
      901 tttaatgata ctacaatagc tgatggtata gctgttaaaa ctccaggaga tttaactttt
      961 gaaataataa atgaattggt tgatgaaata gtagtggttg aagagacaga aattgcagaa
     1021 tcaatattat ttatgatgga aagtcaaaaa atagtttcag aaggtgctgg tgctgtatgt
     1081 acagctgcta tattaagtgg taagtatgta ccagcaaaag atgaaaatgt agtttgtata
     1141 atatctggtg gtaatataga cataaatacg ttatatagaa taataggtgt tgctttagct
     1201 aaagaaggaa gaagatattc atttagtaca attatggaag ataagccagg aaactttgct
     1261 gagttaacta gaataataag tgagaatggt ggaaacattt taagtgctaa tcaaggtaaa
     1321 ttatcagcag gggaagctct aggaaaacaa agtgcggaat ttatattaga gacaatagat
     1381 tatgaccata tagctagaat aaagaaagct atagaagaaa aaggttttaa aattatagaa
     1441 ttataataaa aagtgtatat aatatacaag aaaaatagta taatagtgta tgaagataca
     1501 ttttatgtgt attagattaa cgaattagga ggattttaaa atgaaacatg aagtaataca
     1561 tactaatgat gcaccagcag ctttaggacc atattctcaa gctataaaag ctggaaactt
     1621 gttatttgta tctggacaag ttcctcttgt accagagact atggaagtag ttgaaggaga
     1681 tgtacaagct caaactgctc aatctttaaa aaatcttaaa gctatattag ctgaaagtgg
     1741 agctgatttt tcaaatgtag ttaagactac agtatttata aaagatatga atgaatttgg
     1801 ggctataaac gaagtttatg ctgaatattt tggagaaaat aaaccagcaa gagcttgtgt
     1861 agaagttgct agattaccaa aagacgttaa agttgaaata gaagtaatag ctgtattata
     1921 aaaatacaat atttttaatt tgaaaaggct gaaaaactat attctagtga ttcagccttt
     1981 ttataaaaaa ataaatcaca ataaagaaca tgataaatat tgtcgaatta aaaaataaaa
     2041 ttaaaataaa tattgcaata tttttgagaa ggttttataa tgagtatata atttgaaacg
     2101 tgtaactatt aaattaggca tgagttcttg gatattttta tcctgaggat tcatgccttt
     2161 tttgtattga aattcaaaaa tctatttaat aaggaggaag tactgtgtta aattttttca
     2221 agaaaaataa aagctataag ttacatgcag tagtgagtgg taacagcatt aatattgaga
     2281 aagtaaacga ttctgtgttt tcaaaaaagt taatgggaga tggagttgca attattccta
     2341 atagtaatgt tgttgtagcc ccttgtaatg gtaaagtaac tgtgcttaca gaatcaaagc
     2401 atgcctttgg tatggtctca gatgagggtg ttgaaatatt agtccacata ggaattgata
     2461 cagttagttt acagggtgag gggtttaaaa atgaagtgtc tcaaggagat actgttaaaa
     2521 aaggtagtcc aataataagt tttgaaagag aaaaaataaa ttctcaggga attgattgta
     2581 caacaataat aattgtatta aatcatagcg aattttcaga aataaattgc atggtagaaa
     2641 atgaagttgt tgcagggcaa gatactgtta ttgaaattat gaaataatag gaagggatta
     2701 attcaatatg agagtagtaa aaatctttaa taataatgca ttatctacag taactaatga
     2761 taggaaagaa gctattttac taggtcttgg tataggtttt aataaacgtc caggagataa
     2821 agttaatgaa gataaaatag aaaagattta ttatgttcaa gaccacatgc aaacaaaatt
     2881 tttagaatta ttaaaaaatg ttagtccaga agtgatggat gcttcacaac aaattataag
     2941 tcttatacca ggaaatgagg gaaaatttaa taataaaggg atattatctt tagtggaaca
     3001 tattagtttt gcaatagata gaatgaaaaa taatgttttt ttacctaatt taatgctttt
     3061 ggatataaag atgatgtatt caaaagagtt tgaattagga gtaaaagctt tagaaattat
     3121 atatagagta tgtcatatcc atttgcctga agatgaagca ggttacatag ctttacattt
     3181 tgtcaattta caatcaaatg ataatttggc atatgatact ttaaaatttg taaaaggtag
     3241 tattgatttg attaaagaat gttatggatt agaattagac gaatcgagtt taagtacatt
     3301 acgttttaga actcatctta aatttcttgc tcaaagaatt tttaagaatg aaatttgtca
     3361 ggatgataaa atgattgaaa tgtatgatta tttaattaac aatcatccta aaaataaaga
     3421 atatttagaa aagttaaatg tatatattga aaaggagttt aggtataaat tagataaacc
     3481 tgaaaaaatt tatctactac tacacctaac aaaaatctta taagaatgag atgaattagt
     3541 aatagaaata tataatttta gggggggata agattgaaag aaaaactact tggaggactg
     3601 gaaacatttg caaaggcaat ggttcagcca ttaatgtatt tatcgagtgc aggaatatta
     3661 atggtggtag gtgtactact tacaaatgat atgttattag gagtacttcc attttttaaa
     3721 tgggagccaa ttcaaatatt tggaagccta atttataact gtataatggc tattattaat
     3781 aatcttgctg ttatatttgc tataggtatt cctgctgcac tagcaaaaaa agagaagcac
     3841 aaagcagcgt taataggatt tatgagttat ataatatacc ttacagcttc caacactatg
     3901 ttaacatcac taggtcaact agcaaaagaa agcaagatgc ttggactgat agggactgga
     3961 caagctacta ttttaggtat tcaagttgta gatacaagtg tatttggtgg aattatttta
     4021 gggtgtatag ctggatatgt atttaatcgt acaagcaaca aaacatttaa aggagcttta
     4081 cagatatact cgggagcaaa ttttagtttt atatgcatgt tctttgtatc cattttaatt
     4141 ggagttgtga gtaactttat atggccatta gctcaacaag gaatagcttc tcttgcaaat
     4201 gtcatcaaag atacaggtac atttggttta ttcttatatg gttttttaga gagaatatta
     4261 gtaccaactg gacttcatca tttaatctat acaccatttc agttttctga tttaggagga
     4321 gtgcttaaag ttggtgcaga tacagtttca ggagcctatg ctatagttat gacagaaatg
     4381 aatttaccag ttgagcgttt ctcagatagt atatactaca tggcaactgg atttacaaag
     4441 atgtttggtt atataggtat aggagctgcc tttatttata ctgcatataa gcaaaataag
     4501 aagaaagtta aggcaacgat tattccacta ataattacgg cagtattagc ctctgtaaca
     4561 gaaccattag actttatgtt tgtattctgt gcaccatttt tattctttgt acatgcagtt
     4621 atagctggtc tttttatagc tttattaaaa atatttgatg ttactgcatt atgtggaggg
     4681 aacttattag tatcaattat aatgaatact acagtaggcg tagaaaaaac acactggcca
     4741 gtaatgatga tattaggact tgcacaaatt attgtatatt ttgtagtatt tagtttttta
     4801 attaagaaat ttaattataa aactccaggt cgtgaagatg agagtacagc tacaggcgaa
     4861 gaacaatcaa aacaacttaa tttagatgca gggatagaaa atataattga tgggttaggc
     4921 ggaaaagaaa atattaatac agtagaaaat tgcatcacta gattacgtgt taatgtaaaa
     4981 gatgaaagta agattaatga agatataatt aatttaacgc caaatagcgg gattgtaagg
     5041 aaaggaaaag atatacaaat aatttttgga cttcatgtgc atgaggtaag acgtgcagta
     5101 gaagattttt tagaagctta ttaaagatat atatttatat agcaagggta aataacagct
     5161 ttaagtgctg tttactattt attaaagata catataattt atagaggagg aataattatt
     5221 atgattatta ctattgttgg tggaggaagc acatttactc caggtattgt taagtcaatt
     5281 gcattaagag aaaaagagtt agagcttgag gaaattcgct tatttgacat tgataaagaa
     5341 cgccaagata aagtagctgt agttgtcaac tggatactaa aagaagatgt taaaacagat
     5401 gttaaactaa ctgtaactaa ttgtgaaaaa gaagcgtata cagatgctac atttatattt
     5461 gcacaaatgc gtgttggtaa atatgaaatg cgtgagcagg atgaaaaaat tccattgaaa
     5521 tatggttgtg taggtcaaga aacttgtggt tgtggaggga tggcatacgg actgcgtaca
     5581 atacaaccaa tgataaaggt tattgatgat gtagagaaat atgctaaaaa agattattgg
     5641 atattaaatt actctaatcc tgctgcaatc gtttctgaag cttgtcgtaa gttaagacca
     5701 aatgcaagga ttataaatat ctgtgatatg ccaatagcta ttatagatat gatagcgggg
     5761 tcattaaata tcaatgacgt tcataatata cgctatgatt attttggtct aaatcatttt
     5821 ggctggttta cttcaataga ttataaacat agagacttaa tggaagagat taaggaatac
     5881 ataaaagaaa ataaaatatt attaccaaaa tcttatatag aaaacttaaa taaaagtcgt
     5941 agtacaggaa atcgccatgc tgtaagtagc tggatacatg tttgggaatc tgtttataca
     6001 atgttagaaa gcttcccaaa atatctgcca aacacttatt taacatacta tcttttaagt
     6061 aaagaaacag tggaacattc aaacataaat cgtactcgtg caaatgaggt tatggaaagc
     6121 cgtgaaaaag acttatttga aggtgtgaga cattacttag aaactggaga aatttctgaa
     6181 aaagcatttt atgcaggttc acatggagat tggattagtg atttggcagt ttcaattaaa
     6241 aatgatacac gtagtcgttt tttagttata actgaaaatc gtggagctat accaaacatg
     6301 ccatatgatg caatggtaga aattccagca tatattggta aagatggtcc agaagttatt
     6361 gctcgaggtc caatacctct atttcaacaa ggattaatga tgcaacaact taacagtgaa
     6421 aaattgatag tagaagctta tatagaaaat agttatgaaa aagctttaca agcattcaca
     6481 ttaaataaaa ctattccaag tatgaatgtt gctaaagaaa ttttggatga aatgatagaa
     6541 gttaataagg aatactggcc agaattaaga tagtaggata aaggaaaggg tttttattta
     6601 ataattagat atgttttcag agtcttttat caaaatgtat tcacaaacat atggcaatat
     6661 attaaaataa agagtgatat ttttagaaga atggggtgat gcaatgaaca ttataaataa
     6721 aattttttgg gaagaagata ggattggcat gattacaaat aatttagagg cagatacaca
     6781 tagccactgt atgttacaac tgttcttagg gatagaagac agcattgaaa taacagtcaa
     6841 tgaaaaatta gttaaatgta attgtatcat agtagataaa aatatctctc attcattttc
     6901 agcaagaaaa aaagtttatt actctgctat tattgaacct acatctatat atgcagaaca
     6961 gcttacctca aaaatgaatg attttggcta ctggatatgt gacaatgatg gattagagaa
     7021 attacgtcaa caaggaactt ttttgataga taactctagt aaagaacaat atttaagatt
     7081 tatggaaatg cttaataact atttgaatat acctataact ctcaaacatt atgatgacag
     7141 aattactgaa ttgctcaatt tattacgtac ttgtaattgt gataatcata ctatttcaag
     7201 ttttgcagat aaagtgtccc tatcagcaag tagattatca catctgttta aagaacaaat
     7261 agggatacct ttaaaaagct atatcttatt tcatcaaatg gagtgtgctt ttagagaatt
     7321 actttctggg aaaaatgtta ccgaagcttc tatgactgct ggattcgata ctccatcaca
     7381 ctttgcaggg acagttaagc gaatgatggg aatgcctgtt tctttatctt tgaaagatag
     7441 cgaatttttg aaagtatatt aaatattctc gttatataat gaagttgtac taagaaaggg
     7501 gctttgttat gaataaagaa tatttagagg aaacaaaaat gttaaattat aatgaaccac
     7561 aacttaagct tttggtatca tcaaagaatt ggttggaatt agatgatttt cataaaataa
     7621 aatctattta tgagtttgta cagaatgata ttttatttgg atataatgct tctgatatgt
     7681 taagcgcaac acaggtatta aatgatggta tgggacaatg caatacaaaa gctactcttt
     7741 taatggcatt attacgtgca gtgaatatcc cttgtaggct tcatgctttt gatgtaacaa
     7801 aagattttca acgaggagct acatccaaat tgatttcact attagcacca aaatatattc
     7861 ttcatacttg ggtagaggta ttttatcaag ataggtggat tgctcttgag ggtgtcataa
     7921 ctgataaaaa atatttagaa gcaattcaga agaaattttt taatcatggt ggaacattta
     7981 aaaagtatgc aatagctaca aatgatttga aaaatacatc tattgattgg gatggtaaag
     8041 atacttttat ccaaaaagaa gctatcgtgt atgattatgg tatttttcca tcaccagacg
     8101 tatttttttc tactcattca caacatatgt caaaattaaa aaatttcata tatgtacatc
     8161 ttatcagaaa aataatgaca aaaaatgtat gtaaggctag aaacaattat attgataaaa
     8221 acgaatgagt gtttaagagg taactatata ggaaatatat agaataatta aaactgtact
     8281 ggttaaaatg aataaaaagg agttatcaca gagcaaactt aaattgttca taggataact
     8341 ccttttctgt attaacttct aataatttga tgtcttttta taaaacatat agatacaatt
     8401 aaaccagtaa atgcaagagt agctgctatt gaaaatgcaa catctattcc atgaatgtta
     8461 gacagcatgt ttgaactcat atgagctttc ttagtagcac ttgtcattat agtaataagt
     8521 atagcagaac ctatagctcc agatatctga cggagtgtgt tattaattgc tgtggcatga
     8581 gatataagtt ctctatctaa tgttttaatt ccccatgtag ttaatggcat taaaaccatt
     8641 gaaataccaa tcatacgaat acaatacatc aatgacacat gaattaaaga tgtatctctg
     8701 cctaaaaaag cgaaggataa agttcctaaa aacaaacatc ctgttcctaa tattgataga
     8761 gcatgaggtc catatttatc taaatgacgt cctgcaattg gattgagtac aaccatcaat
     8821 atagcaccag gtaacattaa tgaacctgaa gataatgcag aaaatcctct tacagattga
     8881 acgtacagag gaatcattaa tgtagcagac atcattgagg catatacaat cataattaat
     8941 attgtagaaa taagaaatgg tttattttta aaaaccctca attctaaaaa aggttcttta
     9001 gattttaatt gacgcaatgt aaataaaatt aatgacataa ttcctattaa tattggtaaa
     9061 tatgtggcaa tattagtcca cccataatta ccttgattag taaatccaat taataaacca
     9121 ccaaaaccta gagatgatag tactattgaa ggtatatcta attttagttt ttgagtttcc
     9181 ccaacatttc ttaatagaat aaatgatagt ataacatcta atatagcaat aggggaaaga
     9241 aacagaaata aactatgcca accaaatgaa tctactaacc atcctgataa agttggacct
     9301 attgctggag caaatcctac tgtaatacca actaaactca tagctgcacc acgtttttcc
     9361 tcagggcata aatagagtat aataacttgt aaaagtggca ttagagaacc agaacccatt
     9421 gcctgcaaca cacgagcaat caacatagtt gaaaaattat tagaaaaaag tgcaataata
     9481 catcctatag aaaagataga cattgatgta ataaataact ttctagtact aaatcgattt
     9541 attaaataag ctgttgtggg tacaataata cctgcaataa gtagataaat tgttgttaac
     9601 cactgaccaa tatcagcagt aattttaaaa tctgacatta tattaggtaa tgctgttgac
     9661 aatagtgttt gactgagaga acttataaaa gcaccagtca ttacaattgc tattattaaa
     9721 tttccttttt tattgttact ttgggtttcc ataatttata acgtctcctt ttttaattga
     9781 tttttaatgc tgttcaataa aagtactttt ggtcttaaag tgtcttcttt ttctaaatat
     9841 gcaatcattg catccataat taaagaatca tattgttgat tttttccttc gacgtataat
     9901 ttttttattg cttctagtaa tttaggattt tcaaggagag aagtatcagt tttgattagt
     9961 tcttctatat cttgtatcgt tttaaaaaat agcgatttat tatgaaggga aaagtaaact
    10021 tcatcttctt gtttatgtaa aaacattgat ttttcaatta aaggatttag attatccata
    10081 ttttctacaa ctaaatctag aatttgtata gtaaatttgg caataaagta tacatttatt
    10141 tctctttttt gtacatgaat aatgtatata aactgatgaa ttagagcatc caataagaaa
    10201 actaaatcaa atataatttt ttctatttta tcaccatagt tatcaaataa gcttagtttg
    10261 tattcattca ataagttagc tcttgatttt gtttgcaatt tacttgtagc cttacgttgc
    10321 tcttcagaaa agttttctct tatataggta tttatggtag ttctagaaaa aatatttttc
    10381 catacagcaa ttatctttct gtttaacttt tctgatgatg gaatgtcatt attttcattt
    10441 atggaatgta taatttctaa aaacttttca tcataataat tgattatttc gcagataaaa
    10501 ctttccttag tttcaaaatg cttgtaaaaa gtagctttag acattttaca ctcttttaca
    10561 acatccgata ttgaagtatt ttgaaaacct ttttggtcaa aaattttttg tgcaatagtt
    10621 ataatgagcc tttgtttttc tgtcacttta ttatctcctt tcacgcaaaa acgtttagta
    10681 ctatatagta cctacaagtt ttgataaata tattatacat catttggaaa aaaaatcaat
    10741 atatagactg taatatgaaa tttttgaaaa atttgttgtt atttttagtc gtataaaaaa
    10801 gaaacttaag agtttcttaa gaattgttta aagaagttgc aataaattag tggtatgatt
    10861 atagtatgaa agagaatgtc ttgaaatttt tctgtatcaa attccaatta tggaggtgta
    10921 gtatatgaaa aagaaaattt gtgtagcaat aatttttgct ctatttatag tttttgtaga
    10981 aatgtttatt gatagctcta gcgaaggaag taaaattatg acagctgaat taagtaaata
    11041 caggaaaggc gtaaatgtat tatcaataaa caatattata gtagcgaata aaaaatatag
    11101 tttgcccaaa gattattctc ctcaggaaag cagtgaagcg agagatgctt tttataaaat
    11161 gaataaagat gctcaaaagt caggattaaa tttaaaagct tttagtacat atagaagtta
    11221 tgaatatcaa gatagattat ttaagtcata tgtaaaagaa catggagaaa aagaagcaaa
    11281 tagattttca gctaaacctg gagagagtga gcatcaaact ggacttgctt ttgatattgg
    11341 aggagatgac cagtcttgtt gggcaaataa aaagttcaac aatacaaaag aagctaagtg
    11401 gttgtatgaa aatgcatata aatatggttt tatacttaga tatccagaag gtaaagagaa
    11461 tataacagga tatatgtatg aatcttggca ctatagatat gttggaactg aacatagcaa
    11521 aaactttgca atgaataatt tgactttaga agaatattta catataaatt aagagatggt
    11581 ttgttaaaat taggttaaaa taaaaaataa cctagactat tagctgtgta aagtgatata
    11641 atgtaaatac aatttaagat aactactcga aggggagtag cttacacgaa agtggtaatt
    11701 aatcgtcaag acagtagaaa tactcggtta attagcaagg gattccttga tagcaagacc
    11761 ttcaaaataa gcattaggta tgtttgtttt ggggtctttt tttattcaag gaatttttat
    11821 ttaaaaaaat ttaaatttca agtatacata agagccccca aacataaaat aaatttattg
    11881 aagaggaggg caacaaatgt cttacaaaag tacttatcaa gaagtaatta aaaatttaga
    11941 ctcaagttta tctggtttga gtaaagaaag agcagaagag ttgttagaaa aaaatggagc
    12001 taatgaatta aaagaagcag ataaggttcc tacttataag cttttcctag aaagttttaa
    12061 agacccatta gtaataattc tattgatagc tgctttagta caaatatttt taggtgaaac
    12121 agtggagtct ataataattt ttgcagttat tattataaac tctgttctgg gtgttgtaca
    12181 aacaaaaaaa gcagaaagtt cattagaaag tttgaaaaat ttatctgcac caaacgcaaa
    12241 ggtaataaga gacaataaaa aaatgacaat tccagcaaaa aatctagtag ttggagatat
    12301 tgtattctta gaagctggcg attacatacc agcagatgga aggcttatag aagcacaatc
    12361 tctcaaggtt gtagaaggga tgttaactgg agaatcagaa ccagttttaa agcatataga
    12421 aaaaataagt gaagatgtaa gtttaggtga ccagaaaaat atggtattta gtggtgctgt
    12481 agttgtttat ggtagaggtt cttttgtagt gactggaaca ggtatgaata ctgagatggg
    12541 taaaatagct gggcttttag aaagtgctga aaataaactt acaccattgc aacaaaaaat
    12601 agaggatttt agtaaaaaac ttggtgtagg tattgtaata cttgctcttt taatatttat
    12661 aattcaagta gcaagaaatt actttatggc tggaaatgga gaaatgacac aaattatttt
    12721 agattcattc atgttctctg tagcagtagc agtagcagct ataccagaag ctctatcatc
    12781 aatagtcact atagtattgg ctgttggaac aaatagtatg gcaaaaaaac aagccataat
    12841 aagaaaatta ccagcagtag aaactttagg ttcaacaagt gtaatatgta ctgataaaac
    12901 aggtactctt acacaaaata aaatgacagt agttgattat tatatgtatg gaactaataa
    12961 tgatgagtta gataaagaaa aagtaaacta ttcttatcat gctaaattat tgactatggt
    13021 ttctacattg tgtaatgact ctcatataac tagtgatggt aaagaagttg gtgacccaac
    13081 agaagtggct ttaataaatt attcaagtaa aaatgattta gattatgata aattaagaag
    13141 taagtatatc agaataaatg aaataccatt tgactcagac agaaagctta tgtctactgt
    13201 aaatagtata tatggagatt atataatgtt tacaaaaggt gctccagata ttgtgtttag
    13261 tagatgtaaa tatgctttga aaaatggttc aaaagtagat ataacagatg agataataga
    13321 agaatataaa cataaaaatg aagagttctc aaatagagca cttagagtat tagcttttgc
    13381 aataaaagat gtcccagaag aagattttat accttcaatt gatgacgaac atgacatgac
    13441 attggttgga ataatggcaa tgatagaccc accaagagaa gaagtaatgg atgcagtaaa
    13501 agaggcaaag agtgctggta taaaaactgt tatgataact ggtgaccata aaacaacagc
    13561 agcagcaatt gcaaaagaga ttggtataat ggaagaagga gacttggctc ttactggaaa
    13621 agagcttgat gctttgagtg aagaacaact atatgaaaaa ctagaaaata taagtgtata
    13681 tgccagagtc tcgccggaaa ataaaattcg tatagtaaaa gcatggcaac ataagaataa
    13741 tataacagca atgactggtg atggtgttaa tgatgcacct gcattaaaac aagcagatat
    13801 aggaatcggt atgggaagtg gtactgatgt agcaaaagat gcttctgcta tggtattggt
    13861 tgatgataac tttgcaagta tagtaaatgc tgttgaagtt ggtagaacag tatacagtaa
    13921 tataataaaa tcaattactt atctatttgc aggaaactta ggagctatag tatccatagt
    13981 atttgcagtg tttgcaggtt ggtcaaatcc atttacagct ttacaacttt tgtttataaa
    14041 cttagtaaat gactctttac cagcaattgc attagggttt gaaaagtcag aaaaaaatat
    14101 aatgaataaa cctcctagac acccggatga aagtatacta gcaggaggaa cattgaaggc
    14161 agttgctata agaggttgta taataggtgt agttacaata attgcacaat atataggatt
    14221 acaagtatct ccagaacttg gagtagcaat ggcattttca acattgatat tagctagaat
    14281 aatgcaaaca ttacctgcac gttctaataa tcaaacagta ataaaattag gttttttcag
    14341 caataaatac gttataggag cagttttagt ctgtcttggg ctttactctt taacactaat
    14401 accagtgcta agaggaatat tctctatacc aacaacgttt ggattgtacc agttggggat
    14461 ttgcctaggg ttagcattaa tttcatcaat attaatggaa cttaacaaat taataaatag
    14521 aagtgaagta aaataatcaa aaaattaaag ggcatattga ttttaacaat atgcctttta
    14581 taaatagtct aatttattct atattatcga ttatttggaa tgcttttata acttcaggta
    14641 attctttttc ttcaggcatt ctaaatctta taaaattttt atcaagtcca gtaaaatcac
    14701 ttccagatat aactcttatt tttaatttag caaactcttg ttgtaaatct atgtccttgt
    14761 ttttatgttc aactgtcata attgatacag tatcactagt ttcagctata ttaaggtttt
    14821 tccatggaat taataattga ttttttatat cttttgtttt ttcttttaat tcttctataa
    14881 attgaacatc atctaataaa tttgctgcaa tactacgaga tatttcagac acttcgtaag
    14941 gagtagaaat ctttttaata gggctaacaa gttgttctgg aagaactgca tatcctgctc
    15001 ttagtcctgc taaaccaaat ccttttgaaa atgtttttaa agcaattaca ttatcataat
    15061 tatttagaag cttgacagct gaattttctt ttggcatgta ttcaccataa gcttcatcta
    15121 ccataactgc tatatcatat ttagctgctt cccttactat attttcaatt gatgataaag
    15181 gtataatttg tcctgtagga ttgtttggat tgtctatgta aattacttta tattctggat
    15241 ttattttttc aataaattct ttttcattaa acttgaaatt atcctctttc tttaaaagaa
    15301 cataatcata agttgcacca tgcattttta tatctgtctc atattctgag aactgaggtg
    15361 aatatcctaa aactttatct cccttttcaa taaatagtct atttaaaagg taaataacat
    15421 gtatagaacc atctgccaaa caaattctgt cagtatctaa tgctataaaa tctttccaat
    15481 aatcgactat attatctttt aaagcaattg aatgaggata tcctcttatc atatcaaatt
    15541 ttaaagcatt aaaagcttct acagctttgt ttgagtaaga cacggtattt ataccttcac
    15601 cacagtctat ctcgaataca tcttctgaat gtccagattc tattgcataa ctttttttca
    15661 actgcatttc aatagctttg ttaattttta gtttcatact ttatcactcc ttatttagtc
    15721 aataataaat gttataaaag ttgctagatt taaaatatta tgaaaatata taatagtaaa
    15781 aatgaatata aatattataa tagctcactt tatttaatat gattatatat catatattgt
    15841 aaaatttcta gcattataag actataaatt gaaaatattc agaaaaatac tacaagaaac
    15901 gatttatttt gctcttaaaa taagttaaat gaatgttatt aattttgtaa attgaaatag
    15961 tttaagtata aagttatgat ataatctaat aagggtaatt ctttagatta tattaaggaa
    16021 atataggtat acaataaaaa gttatggagt tggattatgg gatataaatt aattgtaaca
    16081 gatatggatg gaactttatt aggcaataat cataaagtta cagatgaaaa taaaactgca
    16141 ctacaaaaag ttataaaaag cggtattaat gtaactttag caacaggaag agccttcgat
    16201 tcagctaaat gcaatgtaga ttttcttaaa gaggacatgc caataatagc ttgtaatggt
    16261 tcattaataa gagagcaaaa tggaaatata atatattcaa ataagattga tacaagaaca
    16321 tgtttaaaca ttttagatgt attagataaa tacgatattt actaccaatg taatagtata
    16381 gattctatgc tttcgaaaaa aatagaagga cgtgaagata gattaagtgt atttttaggc
    16441 tctgaaacag aagtaattgt aaaagatgat ttgagagaag aaatctttaa aaaagatata
    16501 ctaaaatttg taatcataga agaaaaaaat ccatctattt tggatgaaat aagaaaagaa
    16561 ttgagaaaag ttcaaggaat aaagataacc tcttcatggc caaacaatat tgaagtcatg
    16621 aatgaaggtg ttgataaagg taatgcagtt aaaattttag ctgaaaaaat gaatatagac
    16681 agagaagata taattgcatt tggagacaat tacaatgaca tagaaatgat aaagtttgct
    16741 ggtcttgggg tagctatggg aaatgcagaa gaattgatta aacaagaagc tgattatgtt
    16801 acagatacaa atcaagacag tggagttgca aaggcaattt ataaattcct agagttaaaa
    16861 gaatcactta gctcttaaaa cagtatataa taggaaaaaa taggttgact attttgtaga
    16921 tagtaattat aatacaaata gataaaatat aaaaatttag attcagtgaa aaagagagta
    16981 gatatagaga aaatctcagc gaattggggg atggtgtgag cctaatgata acactttata
    17041 ttgaaaagaa ctttggagaa tactacttga aattcagtat ggtagtaggt aatctcgcct
    17101 taagagaata gagtgggtaa acattgttta ccaactagag tggtaacacg gaatatttcg
    17161 tctcttggtc tttttgacca agagattttt tagtttcatt gagttacaag acttataatt
    17221 aaaatacaaa aaattaaaat atgaggtgaa agttatgaaa ttatggggtg gacgctttag
    17281 aaaagcggaa aatcaactta tggaagaatt taataaatct tttggctatg attgtgtact
    17341 gtacaaaaaa gatatcgaag gaagtgtagc acatgttcat atgcaagtaa aatgtggact
    17401 tttaacagaa gaagaaggaa agtctataac agaaggttta aaagggatac ttgaagatgt
    17461 agaaaatgga aagttagtat tggatggaga gtatgaagat atacatagtt ttactgagat
    17521 aaatttaatt caaagaattg gagatgttgg caagaagctt catacagcac gtagtagaaa
    17581 tgaccaagtt gcagttgata tgagattgta tgctaaagaa aaagcaaatg atttggtgga
    17641 tttaatatct gaatttaaag ctactataaa agatgttgct gacaaaaacc cagtgatgat
    17701 gccaggctat actcatcttc aaagggcaca agtagtgaca tttaagcatc acttaatggc
    17761 atattatagt atgtttgata gagatgagaa aagaataaaa aatgctatag aaatattaga
    17821 tgaatcacct ttaggctgtg gagctttagc aggaactacg catgatatag atagaagtat
    17881 aacttgtgaa caattaggat ttaaaaaagt agtagataat tttatggatg gagtaagtga
    17941 tagagattat ttactagagc taatgagtga tttttcaatt ataatgatgc acttaagtag
    18001 attaagtgaa gagttgatac tttggagttc tcaagaattt ggatttgttg agatagatga
    18061 tttatataca actggaagta gtataatgcc tcagaagaaa aatccagatg gtgcagagct
    18121 tataagaggt aagactggta gagtatatgg aaacttattt ggtcttttta cagtaatgaa
    18181 aggaatacca ttagcatata ataaagacat gcaagaagat aaagaaggtt ttttcgatag
    18241 tgtacatact cttgaaatgt gtatacaaat aatggataga atgatagcca cactaaaggt
    18301 aaatgaggat aaaatgaaac aagcagtaaa aaatggtttt ttaaatgcaa cagaagttgc
    18361 ggattatttg gttaaaaata atgttgcttt tagagatgca catggtatag taggaagtat
    18421 cgttatatat tgtgaagata ataaaaaagc aatagaagat ttaacattag aagaattaca
    18481 aaagttttca gatgctttta aggaagatat ttatgatttt atcgactatg agagtatatt
    18541 aaataaggga ataaaaaaga atttaaaata atgtatttat ttttaaaagc tgtaaatttg
    18601 aatgttatca tttaaattta cagcttttta ttgtgtaaga ttttattata taaaagtaag
    18661 aaacttaaaa ggagtagtat ttaaaataaa tacaaataaa aaattattat taaaatgata
    18721 attaatatca ataagtattg acaaaattat ttctaaatac tattatatat aatataaata
    18781 ataatgaaaa tcaatatcaa ataaatggga ggaaatctaa tgaacttatt agtgattggt
    18841 ggtcatgaaa gaatggaaaa agattatatg gttatggcca agaaaaaagg ttataagaca
    18901 aaggtatata ctaccatgtc atctaaatta aataattcta taggaaaacc agatgcagtt
    18961 gtcatactta catcaactgt ttcacataag atgtctagaa cggttgagtc tcaagctaaa
    19021 aaacaagata tattaatcgt aaggcataaa aatagtagta aggtagcatt taatgaatgt
    19081 ctagatatgg ttgatgaatg tctgggaaat tgttcaaaat gtaagcttaa agacaaacaa
    19141 aaacaaaaaa atatataggt ataaaaaata cataaacata aaattaaaag tactgagata
    19201 atagttataa ttattatctc agtactttta gatttataag gataagtata gtataaattt
    19261 tttattataa tttccaacta cttgttactt tttcatattt tttttacttc tagctttttt
    19321 tctttttttc ttctttatat ttgaagctat tataaataaa actaaaagca ctagaatacc
    19381 tgcaataatc ttaacaaaag tcattaaaac attattttca gtcaaaaatg gaagactgct
    19441 atcaagatta ttttttgcaa ttaagtctat actgttttct agtttaccat tattatatac
    19501 atttaaagta ccaaccttag ctcctttttt tataggcaaa tcaattttat ttaactctgt
    19561 tttggtatca taattgcctt gagattcatc tttttctaag aatatcctat aactattttt
    19621 tggttcataa atcaattcat gttgttttgt aaacaatact tttttagtat ctgtgtattt
    19681 ttctttatca acaatagtag cacacttaaa gttatcaaat ccataatcaa tcagaatacg
    19741 tgagtctaaa tataaatcag cattagttga attaaataca gcaacgataa ctcttctgcc
    19801 atcttttaca gcactcgata aaagacattt accagcagca tcagtatatc cagtttttat
    19861 accatcaact atatcatatt ttatatttat aggttgacct ttgtatgtaa tcttatcatg
    19921 tgatgtcaaa aacttattag tgtttacaaa gtatctctca taaggatatg cttttgtagc
    19981 ttcaaattta agtgacttag tttttacaat ttgtctaaaa gtatcattat tcatagcttc
    20041 tctagctatg agagccatat catgagctgt tgtgtagtga tttgggtctg gtaatccatg
    20101 aggattatta aaatgagtat tagtagctcc aatttttttt gcctcagagt tcatgaggtc
    20161 aataaatttt tgtacattgc caccaccaac atatctagct aatacaaaag cagcatcatt
    20221 agcagaatga accaaaagag catctagtaa ctgctttaca gtaaaagatt ccccattttt
    20281 tagatacata ctagagccat ctatttgagg taaatcttta atttctatta cttgatttaa
    20341 atctttaacc tcctttagaa ctaaacaagc tgtccatact ttagttgttg aagctggata
    20401 aagcttagaa tttccatcct tattatatag tattttgcca gactcatagt ccattaaaac
    20461 tgcatgttta gcaactatag ctggttcatt atctgcaaaa gagatattag agcttcctaa
    20521 aaatgaagta aatatcaata aacagattaa taaaagtgat aaatttcttt tcattgtgag
    20581 cctccaaatt ttaaattcat cttttagtat agcatatatt tgtcaataat taaaagaaag
    20641 gagtgattaa tatatgaaaa aaaaggtaaa atttatttcg ttttttgttt tatttatttt
    20701 aataatatca tcaataatcg tttataaatc gcttattttc aaagatgata tttatgttgt
    20761 aagtaaaaaa aatttaccta atgaaaaaac acatgttgta gagaatgaaa ttaaaggtga
    20821 agataataat cacagtaaag taactaaaga catagataaa aattttcaaa ataataaaat
    20881 aactatatac ataagtggag cagtaaatag acctggaatt gtaactatag agtcagacaa
    20941 gagactttat gatgctgtag aattactagg aggaacgaca aaagaagcag atttaaatgg
    21001 agtcaatcta tcagtaagat tagaagatga acaacattac ataataccta aaataggtga
    21061 agcaacatct gttacaagta atgatgattc caataaacta aatcagaaga atgagtcaag
    21121 aggtgagcct aaaaataaat ccaataaaaa tatatctaac gaatcaaaag taaatataaa
    21181 tgtagcgacg atagaagagt tggattctct acctggggtt ggagaagcta cagccaataa
    21241 aattttacaa cacagagaag aaaatggaca gtttagttca attgaggaaa taaaaaatgt
    21301 aaatggtatt ggagataaaa agtatgaaaa tataaaagat ttaatttgtg tagactaaaa
    21361 tataatacaa aacttacata tagatatgtt attataaata tgtatgtata tgtgtgtaca
    21421 tgtggaaatt tagtaaagga ggcactttta tgaaaaaaga acaaaaaaaa cttacagaga
    21481 tgacaacagc aggtggttga gccgctaaaa tagggccaga ggttctggca tcagttttat
    21541 ctcaattgcc taaaaatgat aatatagaaa atttattagt aggactagat acagcagatg
    21601 atgctgcagt ttataaatta aatgatgata tggcacttat ccaaacttta gacttcttta
    21661 caccaatggt agatgaccca tacgtatttg gtcaaattgc tgcatcaaat tcactatcag
    21721 atgtatatgc tatgggaggc aaacctttgg ttgctatgaa tattgtttgt tttccatcat
    21781 gccatgatat ggatgtactt gcagaaatat taaaaggtgg gtttgataaa gtgaaagaaa
    21841 gtggagcact tttggttgga gggcatactg tagatgacaa agagcctaaa tatggtcttt
    21901 cagtttctgg gattgtaagt ccaaataaag ttttatcaaa tgctactgca aaacctggtg
    21961 ataagttaat tataacaaaa ccaattggag tgggtgtatt aaatacagcc atgaaagaag
    22021 gtatggtaga acaacatata gcagataaag taatagaaat aatgatacat ttaaataaat
    22081 atgcagcaat gagttttgag aaatttgatg taaattcggt tacagatata actggttttg
    22141 gtctacttgg tcatacttta gaaatggcca aagcttctga agtaagtatt gaaattgaat
    22201 caaaacatgt accaattatt gaaggtgcaa tagaaatggc acaaatggga attatacctg
    22261 ctggtatgta taaaaatatg cattatgtat ctaaagatgt agaagttgta ggaaatatag
    22321 aagttgcagt tcaagatatt ttatacgacc cacaaacatc aggagggttg ttaatttcag
    22381 taaaagaaga acttgcagag gagcttgtaa aagatatgaa attaaatgga gcaatagaag
    22441 ctaaaattat aggttctgta gttccaaaag gggaaaaata tattacagtt ttataaaata
    22501 ttatagagaa agagtgattg ttttgagcaa aagagaattg tttgcaatgt tgccttcagt
    22561 tgatgaagta ttaagtgata atagaattgt agaaataata aatgaatatc ctagaagttt
    22621 agttttagaa tctgtgagag aagtaataga tttaaaaaga caatttatat taagattaaa
    22681 agaagatgca tcaaactctg taacaataga gtttggtgaa ataatagaat ctgcaataga
    22741 gagagttaag ttaaattact cattatcttt aaaaaaagtt ataaatgcaa ctggtacagt
    22801 tattcataca aatttaggaa ggtctttact tagtgaagat ataaaagatg aattatggtg
    22861 tgctgcttca aggtattcaa acttagaata cgatttggat aatggagaaa gaggttcaag
    22921 atactctcat ttaactagta caataaaaag acttactgga gcagaagatg tactagttgt
    22981 aaataataat gcagcggcag tacttcttgt acttagcaca atggctaaag gaggagaagc
    23041 aattgtatct cgtggagaat tagttgaagt aggtggttca tttaggattc caagtataat
    23101 ggctcttagt ggtgcagaat tagttgaagt tggttcaact aataaaactc atttgaaaga
    23161 ttacaaggag gccattacag aagatacaaa tgtattgatg aaggttcata caagtaatta
    23221 tagaataatg ggattcacag agagtgtttc tatagaagaa ttggttaatt taggtaaaaa
    23281 atataaacta cctgtaatag aagacttagg aagtggagtt tttatagatt tatcaaaata
    23341 tggtttatct tatgaaccaa ctgtattgga ttctattcga caaggtgcag atgtagtaac
    23401 ttttagtgga gataagatgc ttggaggtcc gcaagcaggt attatagttg ggaaaaaaga
    23461 gtatatagaa aaaatgaaga aaaatcaact tactagagca cttagagttg ataagcttac
    23521 aatatgtgct cttgaagcaa cattgagaat gtatttagat gagacaaaag ctatagaaaa
    23581 tatacctact ttaaaaatgt tgacatataa aattgaagaa ttagaagtaa aagcaaataa
    23641 actatttgaa aaaataactg ctttaaactt aaatgcaaac ataaatatag aagatggatt
    23701 ttcacaggtg ggaggagggt ctatgcctct tgaaactata agtacaaagg taatatcaat
    23761 aactcctgaa catatgaatg tttcatcttt agaaaaaaaa ctaagactta gtgaagcaca
    23821 tataatagcc agagtgtatg ataataaata tgtactagat gtaagaacta tatttgatga
    23881 tgaatttgat gtaatagttg aggaattgag aaaagcattt aattaaataa atttgagtta
    23941 ataaatatta aatttagaag tataagtatg aagttttgat taaaaaatag ctacacacac
    24001 ttgtgacttt agtcatagca ggtttagagg gggcaaaaaa tgaaaaatgt agtaattgga
    24061 acagcaggtc atattgacca cggaaaaact actcttataa aagcattgac tggaagagag
    24121 actgatacgt tagatgaaga aaaaaagaga ggtatttcaa taaacttagg atttacttat
    24181 tttgatttac caaacaatag aagagctgga attgttgatg tcccaggaca cgaaaaattt
    24241 ataaaaaaca tgttagctgg agcatcagga attgatatag ttttacttgt tgtagcagca
    24301 gatgaagggg ttatgccaca gacagttgag catttagata ttctaagctt tttaaatatc
    24361 aaaaatggaa tagtggttct aactaagtct gatactgtag atgatgaatt tagagagcta
    24421 gtaaaagaag atatttgtga aaaaataaaa ggaacttttc ttgaagatgc tgaaataatt
    24481 gaagttgatt ctatatctaa aagaggtata gacactctta ttgaaaaaat agataaaatg
    24541 agtgatgata tagaagataa aaatgaaaac tctccagcaa gacttaatat agacagagta
    24601 ttttcaataa aagggtttgg tactgtaata acaggcactt taatagaagg aaagataagt
    24661 atagaagatg atttggttat atatccacag gtattaaaaa caaaaataag aagtatacaa
    24721 gttcatggag aaaataaaga tacagcttat gcaggtcaaa gaacagcaat caatatatca
    24781 aatgtaaaag tggatgatat aaaaagagga gatgttttag ctgcaccaaa ctcattggag
    24841 gaatcaatga tgttagatgt aaaattatca ttggtaaatc atttagataa aggattaaag
    24901 cactgggata gattaagatt gtatcatgga actagagaga tactttgtag agcagttcca
    24961 ctagataaag aattaattga aagtggagaa agtggctatg ttcagttgag acttgaagaa
    25021 agcatagtat ctaagaaagg tgatacgttt gtagtgagac gttattctcc aatggaaact
    25081 ataggtggag gtgtaataat tgacccatct cctaaaaaac ataagaaatt tgatgaaaaa
    25141 gttatagaag cattaaaaat aaaagaaaaa ggcgaactaa aagatataat agaagagtac
    25201 ttaaaaagga atttaaaaaa ttatccaaat ataaaagaaa taatgagcta tagtggtgct
    25261 catgaagaag atgtaaaaag agcgcttgaa acacttatat cagaagataa agtatttatt
    25321 ataggaaata tgtatatgca tataaatcaa tacaataaat taaaagaaaa tacaataaag
    25381 cttttaagtg agtaccataa gaagtatagg cttagaaaag ggatactaaa agaagaagta
    25441 aggtctaaga tagagagtaa ttttaagact agggagatgg atattttatt agaaaaattg
    25501 tctacagaaa atgctataaa aatagaaaat aatatagtat ctctattaga ttttgaggtt
    25561 attttaaatg ataagcaaaa agaaatagca aaaaaaatag aaaaaagatt aaaatcatgt
    25621 ggagtttctt ctatactgac aatagatgaa gtttctgaag gaaatcataa ctatgctgaa
    25681 gtattggagt caatgatagg taataaagta gagaaattag atgatttgta tataatggac
    25741 aaagatattt atgaaaatgc aaagaacatt ttgataaatt atataaaaga aaataaagaa
    25801 ataacattag gagaatacag agatttgatt gattctagca gaaagaattg catgattata
    25861 ttggaaaact tcgatagaaa caaaataact aaaagagtag aaaacaaaag aattttgttt
    25921 tagcagaaaa tgtctgtttt tgctttaagg tataaagaag gaattataat gtcgagtatc
    25981 gtataattaa ttagtataaa atattaatta agaggaagtg taaagtattg aagaatataa
    26041 tacctgatgt aaaaccagat ataaaagaaa gagaagacat gagcctttta tttataataa
    26101 tgggctcagt acttttatta tttattataa aagatataga gaaatatgaa actttattac
    26161 atgccatata tacgatattt ttagtagcta caggagtaat tatatttaat actacaaaat
    26221 ttaaagtaga ttcattttct acatttttag gattaatttt tatagctact ggagtattgg
    26281 agtgtatata tttatttaat tccttgggga ttaaaactaa gtctataatg gagattaaca
    26341 tcacaatatc agcaataaca gatttatttc ctatactggg tgtatactta agttttaaat
    26401 ttgttaagga taacaaacaa atttattcaa gtgtaatttt atttatagca actgctacat
    26461 taacaataac atctttattc ataatatcag gaatttgtga ctatctggga aatggtaaat
    26521 cacaatatgc tttaggagtt ataatatcta tattcataat aattatttct atcattagtg
    26581 gaattgaatt aaattcaagt tcaaataaag gtaaatggga atatgatgaa aaaaagattt
    26641 ttaacagaat aatagtaata ataatcttat caagagttcc aaatctattg catatagtta
    26701 ttgataatag aaatgtagag aggatattat cacaaataat aataaatgta gccttatatt
    26761 atttatataa ttacatagta tctaagaata ttaagaaaac agcactggaa ttgcatgata
    26821 cgaatgaaga attaacaaaa aaaacggaaa gtttaaaaga aaagaataaa aaattaatct
    26881 atgagacaga aaagatagag gaacttaagg gaatacttat gaaaagagaa tctaggctac
    26941 aatctacatt agatgtagca gtaaatagca tagtagtatt tagcaaagat ggagaaatta
    27001 catatgcaaa taagagcttt agaaatactt ttggagacta taaagaacaa gataaattga
    27061 ctgataaaat aaaaaacttc aatgatttga tagaaagcat tcattatgtg tttgttcatg
    27121 agaagaatgc agagaaactt attagtacaa gcgataataa agtttatcaa gctatatttg
    27181 cacctttaat tattgcttca caaacagaag gagtattgtg tgtactagaa gataagacta
    27241 agaaaaagga gtacgaacgc aaacttattg aagcaaataa gagaagtaaa gattttttag
    27301 aaagtattgg agatggcata gtagtgcttg aaggtaataa caaaatatat gttaataatg
    27361 catgtaggga aatttttaaa aataatttag agagtattga tttttcatta gtatgtaaaa
    27421 gtgaagaaag tatagaaaaa agatatgtaa tagatggtga agtaaagtat gtagagatga
    27481 gtttttctca gtatactaat gctggtacta ataaaactat tattgtaata cgtgatacaa
    27541 cctctcgaaa aatatctcaa ataaaacttg aggaaagtca atcatcatat tcaagattta
    27601 tagatatatt acctgatggc atatgcttat taaaagaaga tttaagtata aactatgcaa
    27661 ataagtcgtt tttagatatg ctagctttta caaacataga tgatataaaa gattctaata
    27721 ttaaactatt aatgaatgcg aatactgaag aaaaaatgaa atttacggat aatatggcta
    27781 aagttttaaa tgaaaataga agtatacttt tactggaaca tgaattgata aatagttatg
    27841 atgatatagt agaagtagaa ttaagtgcat taccttttgc tatatacaat actagataca
    27901 taatgcttat tataaaagat ttagtacata agaaatattc cgagcaagca gaaaaagaac
    27961 tgcttgaaag atttaaaaca gataaaatca aaacggagtt ttttgcaaat atgtctcatg
    28021 aactaaaaac tccactaaat gttatatcta gttcaaatca actggtagat tctttctata
    28081 gaaatgaaaa gataaaagat tacaataaca atattaaatc tcatgtggat ttagttagac
    28141 aaagttctta taggcttcaa agattaataa ataacattat agatttaaca aagatggagt
    28201 ctgggttcta tacactaaaa cttgcgaaat acaatattgt atctgtaata gaagacttat
    28261 ttatgaatat agaagagtat gcacttagaa aagacataaa aattcttttt gatacagacc
    28321 ttgaagaaat taatgtttat atagacaagg ttgaaattga gagaattatg ttgaatctat
    28381 tgtcaaactg tattaagttt actgataatg gaggctggat atatgtaagt attcattata
    28441 aaatagataa agtaatcata agtgtaaaag acactggagt tggaatacca caagataaat
    28501 tagagttgat ttttgaagaa ttttcacaag ttgataagac tttatccaga aatactgaag
    28561 gaagtggaat agggcttgct atagttaaga atctagtaag tcttcatggt ggagatatag
    28621 aagtagtaag tgaagtgaat aaaggcacag agttcttaat ttcacttcca atgaagggat
    28681 ttagtagtga acattacaca gaagataaga gaatatataa tattcaagaa aaaataaaaa
    28741 tagaattttc tgatatatat tattaaaaat gattatgagc aaaaataaaa taaaaatact
    28801 atttgtttaa atatttaagt tgtaagaaat aggctatcat aaggtaaatt attatgatag
    28861 cctattttta gctaggtttt atatctatat gtgagaacat ataatctcta aattaccttc
    28921 aaaactaaaa tctccaaagt cgtttggcag tataaaatgc ataccctttt ttaaattata
    28981 ttctacagaa ttgtgtataa gttttccatt tccatccaac acactgtata aagaaaaagg
    29041 tgtattgtgt gtaaaattac attttccaaa aacatctaat ttataaacac taaaaaattc
    29101 gtttgacaca aatgttgtgc atttaaagtc tgatgttgat acgattttat agtcagtatc
    29161 gaaatttata tgaggaacat tcgtaacatc tattgatttt tgaacatgaa gttcacgctt
    29221 attacctgaa ttgtcagttc tatcataatc atagactcta taagtagtat ctgagttttg
    29281 ttgagtttct aaaatcaatg ttcctttgca tatagcatgt atagtgccac ttggaacata
    29341 gaaaaagtct ccctttttta tattaacctt tctaagtagt ttgtcccatt cattattatt
    29401 taccatattt acaaattctt tatgagattt tgcattatga cctattataa tttctgcatc
    29461 atcagaacaa tctattacat accaacactc tgtcttacct aactctccat tttcattttt
    29521 tttagcatat tcatcatttg gatgaacttg aactgataaa ttatcatttg catccaatat
    29581 ttttgtaagt aaaggaaact tatcaccagg tgtgtttcca aataattctc tatttttatt
    29641 ccacaattca gatagttttt tacctttata ttttccattt tctattaagc aatctccatt
    29701 tttatgagag cttatagccc aacattcacc agttgttggc gaatctattt cataattaaa
    29761 tttatcttta agtgcagtac caccccatat tctatccata aaaataggtt ttaaaaataa
    29821 tggttccata atcctgttcc tcctatgata ttaaatttat cctacaaata attatatata
    29881 aatagattat aaaatcaata gtaaaaaagt tttgtccctt gaaatgacat aaagtataag
    29941 gagttattaa ataagataaa ctatgatata taatataaag ttctaaattg gagtgataat
    30001 tatggagttg tttaaggcag aaagcaaaaa atataaaaaa gaatttttaa aattattgga
    30061 gcaatgggtt agtatacctt cattttatga tagaaaaact gtatctaaag acatgccttt
    30121 tggaaaagga gtatatgatg cattaaactg gtttgaaaat ctaggtagag aaaacaattt
    30181 caaagtaaaa aatatagata atcatgctgt tcaaattgaa tatggaaatg gtaaagagta
    30241 tgtagatata tttggacatt gtgatgttgt aaatccaggt gaaggatggg atagtgaacc
    30301 atttaaacta aatattatag gtgataaatt agttgctaga ggtgtatctg ataataaagg
    30361 gcctatgata gtgaattttt tagcactaaa aatgataaag gatttagata ttaatttaaa
    30421 aagaaaggtt agattaatag ctgggggaaa tgaagagagt ggatttaaat gtataaagca
    30481 ttattatagc aaagagccat atggtgtatg tggatttact ccagatgcta aatttcctgt
    30541 attaaatgga gaaaaaggtg gagcaataat aaagttaatt tcaaatatag acgataaatc
    30601 tttatatata agtggtggaa tagagtttaa tacaatacca gataaagttt atataaagaa
    30661 tgtagaaaaa ttgggtaaag ataatatatg ttttgatatt aacaatatat cgataaatta
    30721 tgataatggc aattatattg tgtatggaaa aggtggtcat tcatctaaac ccgaaaaatc
    30781 aataaatcct atattagcta caattaaact tttgtcagaa aatattgatg aaaaatggac
    30841 aaaagattta tataagttga taaatcaaga taatataaat ggaaacttat ttggtttaaa
    30901 tattgagggg aaatgtggaa ttttatcaat ggtgccaaca ataataaata tagtagatgg
    30961 aaaattagaa gtagttttaa gcgttagata tccagaaata ttaaccattg aagatataat
    31021 aaaaaaattt aatttgtata tggagcaaaa taatattaat aaatttgagc ttattgggga
    31081 aaatttaaag caagcaaatt atatagatag aaattcaaaa cttgtaagaa gtttgcatga
    31141 tatatatata aagtattctg gagatttaaa aaatgatgtt agagtaacta gtgcaggaag
    31201 ttatgcttct gaaatgaata attcagtaat atttggttgt gaatttcctg atggtagctt
    31261 tggcaatgtc catagtgcga atgaatttgc tagcttagat agatttataa ctgcaatagg
    31321 tatatatgca gaggcaataa ttacattatg taataaaata taaatacaaa atgtccctta
    31381 tatagacata ttatatatac aattaaaatt ttacttgata tataattgaa atcaaagaga
    31441 aggtgataca atgataacta agaaacatgc aataatagta aagagtttaa gcaataaaga
    31501 tggatatatg acatcaaacg aattagctat caaattggat gtgtctacta aaactattaa
    31561 aagatatata gcagatttaa atagtgtttt aagcaaatat gatttggtaa tagcttcttc
    31621 tagaggtata ggatacaagt taagcggttc taaaaacaat atagccagag ctgttaaaga
    31681 agcaaataaa tatattgatg gttttttaga tgactctgaa gagtcaagaa tgtcaaatat
    31741 aatatgtatg cttattaata gaaattatat gagtatagaa gcaatggcag aagaattaaa
    31801 tctaagtata gccgctataa ataaattgtc tagtaagctt aaaagaaaac ttgaaaagta
    31861 tgacttagtt ataaaatcta aaccttacta tggaagctat atacatggtg aagaaattaa
    31921 tataaggcaa ttaattactg actatgcaat aaaattagat gaaaaaagta aagtgaaggt
    31981 gtttttagat gacattagtg aaaacgatat acactgtata gaaagtattt tagaaaagca
    32041 cttaagagaa aaagatacaa taatttcaga taaagatttt aatcttttgc tttcaaaaat
    32101 aatcgtttct gtatttagga gtaagagagg tcatagtaac aatataaact taatggatac
    32161 aagttataga tttcataact actactttat agaaaatcta atgaaagaaa tatctgataa
    32221 aattggattt aaacttattg aagatgaagt aatttatatt tcaaattatt ctggtgtaat
    32281 agcctataaa ggtacacaag gaagaaaaaa cacaagtgaa attgaggaac gaataagtag
    32341 tgttataagt agtgcacttc aagatatatt ccttatttca ggtagtgatt atacaaaaga
    32401 tgatgagttt atggttgcaa tctctgacca tataaagaga tttttaaata gagctagagc
    32461 taatgtaaaa tcaaataatc ctttacttca tcaaataaaa gagaagtttc ctatagcttt
    32521 taatttagcc gtgtttttat caaataaact agaaactgag tttaatttaa aacttgatga
    32581 agatgagctt ggatatatag ctatccactt tgctgcttca aatgaaagaa tgaaaaaaaa
    32641 tactagtaag aaaatttgta tagtttgtca ttatgggata ggaacaggac aacttatttc
    32701 tgaaaagcta aaacagaata taagtgattt aagtgttgta ggtgtttatc cagttagata
    32761 tctcgatatg gctataagtc aagatgttga tttgatagta tctaccgttg aattaaaagg
    32821 atatgaaaaa cctgtcttat atatagaaaa tatatttgat gatagcttaa ttgaaaacgt
    32881 aaacaaagcc ttttatgaaa aggaagaaag aagaaagata ataagcaaca tgtttgatga
    32941 aaaagctttt ttcagtataa aggctaatac taaagaagag gtcataattt cactttcaaa
    33001 taaactaaaa gaaagagatt ttatagagga aagttctata aaaagtataa tagatagaga
    33061 aaatatttca tcaactgaaa taggaaatct agtagcaata ccccacacaa tagtgaaggg
    33121 agataaaaaa tctataatag gagttggaat acttgaaaat ccaataattt gggataagca
    33181 agaggttcag ctagtattta tggtattttt taatactaaa gaaaaacata atttctcgat
    33241 atttaaatac ctttataatt ttataaaaga tgaaggcgga gtaagaggaa ttattaaaat
    33301 atgtgacttt aataaattaa tggcactgat aggtaattaa ggaggaaatt aataatggga
    33361 acaaacatat ttaacaaaga atatgtattt ttaaatgttg atgctaagtc aaaggttgaa
    33421 gttttaaaat ttatatcaaa aaaagctaaa gacttaaact tggcagaaga tgagagctta
    33481 gtatatgaag gtttaatggc tagagaagaa caatttacta caaatttagg agaatctata
    33541 gcaatacctc acactaaaaa tgatgcaatt gaaaatccag cagtagtagt attgaagttt
    33601 aatgaagatg ttgtttggaa tgaaggtgag gataaggtta aattagcaat aagcttactt
    33661 atgccaggaa aaagtaaaga gaatattcat cttaaattat tatcatctct ttcaagaaaa
    33721 ttaataaata aagaatttaa agattctctt ttaaaaagtg ataatgttga agaaatatct
    33781 aacttaataa atgaagcttt aggtttataa ttaaacacta aggttataaa ataaaaaaat
    33841 aattaactaa aaataggagg aatttgaaat gaataaaaaa ttagtagcat tatgtgcttg
    33901 tccaatggga ctagctcaca ctttcatggc agcagaagca atagagcaag cagcaaaggc
    33961 attaggttat gaagcaaaag ttgaaactca aggtgctgat ggtgtacaaa atgagttaac
    34021 aagagatgat atattaggag caactatgat aatacatgca gtagcaataa caccagaagg
    34081 tatggaaaga tttgatggtt gtgaagttta tgaagttgaa ttacaagaag ctataaaaaa
    34141 tgcagaaggt gttataaaag aaatagaaga agatttagga atataataaa tttattgtgg
    34201 aggaaataga atggcaatta agaaaaaagt tataaacagt tcaggtgctt ctacaacagg
    34261 aggaaataat gtaggaaaat ctactccatc tagtccaact caatcaaagg gaaatggaaa
    34321 atggaaagaa ataagtaaac atataatgac aggtatatca tatatgatac cagttttagt
    34381 aatgggtgga cttatagggg ccttatctca attaatacca tatgctatat taggacttga
    34441 cccatctgta ggtatagttg atgctatgaa ctcaggagaa tttacagggt tcaagcttag
    34501 tcttttaaat atagcacaat taatgtcaaa tttcggattt actttgtttg gatttgcgat
    34561 accactgttt gcagcatttt gtgcaaactc tataggtgga aaaacagctt taattgcagg
    34621 atttataggt ggatatatag ctaataaacc tgtaggtgta ccacaattcg ttgatggaca
    34681 atggactgaa gttgttccag ttgcatcagg atttttaggt gcaatactaa tagcatttat
    34741 aataggatat tttgtaaaat ggttaaataa atctataaaa gtttctcata actggttagc
    34801 ttttaaaaca acatttttaa taccattaat agcgtcatta gcttgtatgg tattgatgat
    34861 atttataata actccatttg gtggattaat taatgaaagt atgaaaaact tcttaacagc
    34921 agcaggagca gctggagaat atgtatatgc aacagctttg gcagcagcta cagcattcga
    34981 cttaggagga ccaataaata aagcagcagg attcgttgca cttggtttaa ctacagagaa
    35041 tgtacttcca ataacagcaa gaacaatagc tatagttgtt cctccaattg gattagggtt
    35101 aacaacatta ttagataaaa gattagtagg aagaagagta tatgatagac aattctatca
    35161 agcaggaaaa acttctatat tcttatcatt tatgggtata tctgaaggag caataccatt
    35221 tgcacttgag agaccaggtt ttgttatacc tttaaacata gttggaagtg taataggagc
    35281 tattacaggt ataattctag gagcaattca atggttccca gagtcagcta tatgggcatg
    35341 gcctctagta gataacttat ttggatatat aataggtata gcagttggtg ctatattcat
    35401 agcagtagga aatatattct atagaaataa attaataaaa gatggtaaac ttgttgtaga
    35461 ttatatcgac tagtatttaa tttttactat ctataaataa ctttggctgg taatatggtt
    35521 ttaatcaata ttaccagcct tacctatatg attaattaaa ggcggtggag ataagatatg
    35581 gataagatag aaaaagtaag agagtatttt agagaatatg atatagatgg atttcttata
    35641 aatagtccta caaacaagtt ttatgttgga aatttattta gctcttcagg ttatgttttt
    35701 ataacgaaag aatcacaata tataatagta gattttagat attttgaaga aattaaaaga
    35761 aaatctagtt tgtttaatgt agtattaatg gacaaaacta gaactcattt tgatataatt
    35821 aatgatattt gtagagagca gaatataaag gaaattggat ttgagggaaa tgaagtatct
    35881 tttgatttat atagaagtat gagtaataag ttaagtgcaa ccttaaaatc agttgattta
    35941 tctacattaa gggaaacaaa aaatgaagac gaaataaaat atataaaaaa agcttgtgaa
    36001 atagttgatg ctacatttta tcatatagta gactttataa aggttggtat gactgaaaag
    36061 caagttgaaa atgaaattgt tagaattata aaagatttag gtggtcaaaa agaatctttc
    36121 gatacaatag ttgcatctgg gcttagagga gcattacctc atggaaaagc aagtgaaaaa
    36181 gttatagagt atggagattt tgttaccttt gactttggtg ctaagtataa taattattgt
    36241 tcagatatta ccagaaccat ttgtatgggt actataaata aagagttaga agaaatatat
    36301 aatatagtaa gaaaagctaa tgaagagtgt ataagggttt taagaccggg aatgactact
    36361 ggagagatag ataaagttgc aagagacata attggttcat atggatatgc tggtaatttt
    36421 ggtcataatc tgggtcatgg tgtaggaatt atggttcatg aatatcctgc attagctcct
    36481 gaatcaaatg aagtattaaa agaaggaatg attgtaacta tagagcctgg tatatatgtt
    36541 ccaagtcttg gaggcgtaag aatagaagat gatgtactta taacacaaga tggatgtatg
    36601 agattgacta catctactaa ggatttaata gttgtaagct aaaaataaat tagataaata
    36661 ttttataaca ataagaaaag aagaggtaaa tttaaatgta taattttgat gataaaccag
    36721 atagagtaag tgaaaagtgt agaaaatggg atttaaatat tataagagat aaatttggag
    36781 atattagaga agattttata ccaatgtgga ttgctgatat ggattttaaa ataccaacag
    36841 aaatagaaaa caaatttatt gaagctgtaa gaagaggtgt atttggatat acatactgtt
    36901 atgatgaatt ttatgattca gttattggtt ggcaaaaaaa tatgcatgag gtaaatgtag
    36961 aaaaagaatg gattacatta acttatggaa ctgtatcaac acttcattat gtagtacaag
    37021 ctttttgtaa gaaaggtgat agtataatat taaatacacc agtttatgac ccctttgaat
    37081 catcagcaaa aaaacaaggt gtaaatgtaa tttgtaatac attagatgtt gtaaatgata
    37141 gatattatat aaattttgat aaattagaag ttcaaattaa agaaaataag cctaaattaa
    37201 tgatgttttg tacaccacat aatccatctg gaaggatatg gacaattgaa gaaatgacaa
    37261 gggtagcaac tatatgtaaa gaaaataatg ttattttggt tgcagatgaa gtacatgcag
    37321 agcatattca ttatggtaca tttaattcaa tacttaagat tggaaaagag cttttagaaa
    37381 atgttattct attgacatca ccaaataaag gatttaatct tggtggatta aagacttctt
    37441 attcaatagt tataaataag gatataaggg acaaatttag aaataaatta aagcaaaatt
    37501 ctataacttc tccaaatgtg tttggaataa taggattgat aaccgcttat aatgaatgtc
    37561 atgagtggtt aagtggtgta aatgaatata taaaatcaaa ttatgaactt ttagaaactt
    37621 gggtaaataa atataataag ataaaattga tgaaaatgga atcatcttac ttagcttgga
    37681 tggatataag tggattaggt attagtgcaa gtgagtttac agataaattg gctatagata
    37741 caggagtatt attagaagat gggagtcatt ttgtaaaaga tggtgagaag tatgttagaa
    37801 taaatttagg aactcaaaag gaaaatgtaa ttgaagcttt aaatagaatg gatttatttt
    37861 taaagtcttt ataaaaattt ggttgaatta gtattttata taaatttaaa ctattaatat
    37921 ggtatataca taagtagaat ttgttttaga ttacttaagt atataccata ttttatataa
    37981 aaattaaatt tgcattagtc atgtgataac tatttaaatt catatgtatt ttgtatgtat
    38041 aatagatata attattattt aaacttattg tttatttaat ttttcaatag aaaaagattt
    38101 atctgtaagt ttaaaattat cttttatacc cttagttaag tatactttct tatccttagt
    38161 tatgaatata gcatctacat tatcaatttt attaattaaa ttcatacctt tttcaagacc
    38221 aagaccaaat gtagaagtgg ataaggcatc acaattaata gatttatcag agattattgt
    38281 aacactactt aaattgtttt caaaaggata ccctgtaaat ggatttaaca tatgatgata
    38341 tatttttccg tttttttcga taaatctttc ataaattcca gaagtaacaa cagacttatt
    38401 tgtagtttct atgtttccta tggattcacc atttttacta gttgggtctt gaatacctat
    38461 tttaaaaggt ttatcatttt taccattttc taaagtaaat atatttcctc ctaagtttac
    38521 taaacctttt tttacgtcct ctgattttaa ataggctaca attttatcag cagcatatcc
    38581 tttagctatg gcacctaaat caattttcat attttctttg gttaatttta tagatttatt
    38641 tttttcatcc aatatgatgt tcttataatc aataagaggc agaagttttt gtatctcaga
    38701 atcacttgga actttagctt tatctgttcc aatagcccat aaatttgata atggaccaat
    38761 tgttatgtca aaatatccat ctgataattt ggaatattgt atagcttctt ttacgacgaa
    38821 aaatgtatca tcagaaactc tgacaaattt tttaccagca ttatcattta ttttagaaac
    38881 atcacttcct ggtatatgag tgctcatttt gttgtcaata tatcttaaaa ttgaatcaca
    38941 ttcatttaag attttatcac ttttggattc ttttacatta aatacagtaa cttcgtttac
    39001 tgtaccaagg tagtagctag ttttactata tttagtattc tggcttgaac tcctaaaaaa
    39061 tgaaaataaa attaatgcta aaatcaatat cacaaaaata aatgtgattt ttttcttatt
    39121 catggtatat tcctcctatg aaattgtgtt attattttat tataacataa tttcatagga
    39181 ggacaaaaaa tgaagaaaaa agacattctt cttattttag gcattttggt tgttattaca
    39241 gcatgttatg ggataataaa tgttataaat tctaaaaatg ctggaaatat tgagatttat
    39301 gtagataata aattgtataa aactgtttca ataaatgcca aagaagaatt taaaatagag
    39361 aatagagggg ggtataacat agtaaagatt catgataaag gggttgagat agtagatgct
    39421 tcatgtcctg ataaggtttg cgtacatact ggatttataa acaagccaag tcaaagcata
    39481 gtttgtatac ctaatagagt gagcataaaa ataaatacaa atgaaaagaa tgataatcaa
    39541 gaagatataa tttctaaata aaataataaa aataattgaa aggaattggt gataattatg
    39601 gttaacttag gaaacgattg ggatgaatta ttgaaagaag aatttgaaaa agattactac
    39661 ttaaacttaa gaaaatttct tatagaagaa tataaaacac gccaaatttt cccaaatatg
    39721 cacaatatat atgaagcttt aaaacacact tcatacaaag acacaaaagt cttaatatta
    39781 ggacaagacc cttatcatgg agataatcaa gctcatggtt tagctttttc agttcaacca
    39841 caagtgaaaa ctccaccatc tttattaaat atgtataaag aattaaaaga tgatttaggt
    39901 tgttttatac ctaataatgg atatttaatg ccttgggcag accaaggagt gttactttta
    39961 aatactgctc ttactgttag agcgcatgaa gctaattctc ataagaacaa aggatgggaa
    40021 attttcactg atagagtaat atctatttta agtgagcgtg aagacccagt tatttttgta
    40081 ctatggggaa gtaatgcacg taaaaaagta gagttgattg atacaagtaa acattatatt
    40141 ttggaagcac ctcatccaag cccattgtca gcaagtaaag gcttttttgg atgtaaacac
    40201 ttctctaaga taaatgaaat tttgaaaaag ctaggaaaag aacctattaa ttggcagata
    40261 gaaaatatat aaaagtaaaa ggtaacaaaa tgataacaaa acaacaataa acaatgacat
    40321 tgttgtaact aatagaaata tgcttaaata gttgaaaata ctatgtatgc atatttctat
    40381 ttttttgtca agttgacaac tcttgaaaaa atagttacaa tttagttaca caaaaaacac
    40441 aaataaaaaa agaaacttac aaagcagaat tttatgaagc aaaatatata gtgtaaaaaa
    40501 tcttagggag gaaattttat atgaatttta aaaaattgag taatgctaaa gtctcggtaa
    40561 tggcagttgt tttatcagtt ggaatattat cgggatactc tgcgcttaat aaacaagtaa
    40621 cattagtagt aaggggagaa gaaagaacta tatcaacatt tagttctaat gtaggagacc
    40681 ttttagaatc tcaaaacatt agctatgatg caaatgatat agtaacttta gatgaaaata
    40741 caaagttatc taatggagat aaaatagaag taattgatgt aaaggaaaaa acagttgtag
    40801 aaactaaaga cattccattt gaagttacag ttgttgaaga tggctcttta ttaaagggtg
    40861 attctaaggt taaagaagaa ggaaagtctg gtaaaagtga attaatatat aaagaaactt
    40921 atcacaatgg aaagaaagta gaaaaggaat ttgtgaaaaa ggttgttaaa gctgagccag
    40981 taaataaggt tgtaagcaaa gggacaaagg tagaaatgca agtagcctca tcaaggggag
    41041 aaagttcaag aagaatggct tcatcatcat ctagtagcag tagtagtaac aatggtaaaa
    41101 atatgagagt ggtagcaact gcatatactg gtcacagtat aactgcaaca ggaacaaaac
    41161 ctaagtgggg aacaatagct gtagacccta aggttatacc atatggaact aaagtttata
    41221 tacctcaatt tgacatggtg tttactgcag aagactgtgg tggagcaata aaaggaaata
    41281 aaattgatat ctacatgaat gattcaaaaa cagtttataa ctggggaaga aaaactatag
    41341 atatacgtat attaaaatag ttaaataatt tatattttta ctggaaatta tattttgatt
    41401 atatagagaa gaaactcttt atagattcta aaaatataat ttccagtttt ttattttgga
    41461 tatgtaataa aacaggtaaa ttttaaccat gtatagataa aagctattta aattataatt
    41521 tactatcata taaatctata aaaattgttg caaagagtca aaatatatga tattatagat
    41581 ttcgttgaga aggatttcat tatgggagtg gatgggtgcc ggtgtgccct ctagtcttca
    41641 aaactagtat gaggggttaa gagcctctta ggtgggttcg attcccacgc attcccgcca
    41701 atatgtaaaa ggtatctttt aattaaaaga taccttttta aatttgtttt aagataattt
    41761 agttttaatg atatataata ttttgtatta tataatgtaa attttataat actattattg
    41821 ttcagataaa agtctaggag agtgaaaaga tggaaaataa ttttacaacg agaactagtt
    41881 ttctagttgg agatgatggg atagaaaaac ttaataattc aaatataata gtatttggag
    41941 ttggaggagt tggtagtttt actgttgaag ctttagcaag agctggagta ggcaatatta
    42001 ctattgtaga ttttgatgat gtagatataa ccaatataaa tagacaaata ccagccctac
    42061 attcaactgt aggaagatac aaagttgatg tcatggaaga aagaatatta gatataaatc
    42121 ctaatatcaa tataaaaaaa ataagaagtc tttataataa agatactagt gacgaaatac
    42181 taactgaaag atatgattat gttgtggatg cgatagacat ggtaagttcc aaaatacatc
    42241 taattgaaac ttgtgaaaaa aaaggattga aaataataag ttctatgggt atgggaaata
    42301 aattagaccc aactaaaata gtcgttacag atatacacaa aacaagtact tgtcctctag
    42361 ctaaagttat gaggaaagaa cttagggata gaggtatcaa aaagttaaaa gtagtatatt
    42421 ctactgaaca accaatagaa cttaagaaga aagtaatgaa tggtagaaaa gtaacacctg
    42481 gtagtgtatc atttgtccca tctgtaggag gtttaataat cgcatctgta atagtaaatg
    42541 aactattagg acaataagtt ttaaatattt taatttataa attttatata caaatttgaa
    42601 ggctagaagg atgaatataa agcaatttta tattcatact tttagcctag ttattttata
    42661 ttaccttatt ttatgtagtt gtagctttat tttttagatt atgtatctat ttcataatta
    42721 tattttgtaa atataatttc tccatcacta taaaaaacaa tatctcctat tctgtctgtt
    42781 ctataaattg atacatggtt ttgttttaga ttattaataa cctccctatg tggatgacca
    42841 tattgatttt tatatccaca tgatattgca gctatatctg gactaatttt ttttataaat
    42901 tctaaagatg aagaagaatt acttccatga tgacctattt ttataaaatt aatattattt
    42961 aatttaaaag aatgtaaaat ttctttttca ttttcttctt cagcatcacc cataaataaa
    43021 aaagaattat cattaaaagt taatttgaaa actatagaat ttaaattaga ttcttcttgt
    43081 atatatgatg gacttaatac atatatattt atattgttat ctatgtttaa aacatcattt
    43141 ttatagagat gctgaataga taagttttta tccgtacaag aatttattag attttgataa
    43201 gcctcactat cagttgattg ttcaggcata tatatggagt ttacattaaa tttttttata
    43261 atattatcaa gacttcctat gtggtctgaa tctggatgag ttgctattat aatatcaata
    43321 gtttttattc ttttttgtct aagataacta ataattatat tttcgctatc ttcatcacct
    43381 ccatcaatta atatattctt atttgtgggt gtttgaacta aaatactatc accttgtcca
    43441 acatcaatca tatgtataga tagtagagat tttttgtcac agccgattaa aagtgatatt
    43501 ataataagta ttgataaaaa aattttattt ctcaataaaa aatcactcca ttcattacat
    43561 gtttatataa atttatgatg ggtaatataa gatatatatg acttattata ttttatattt
    43621 taaacaatat aaatgaaatt aataccataa taaaattgga gttttttata tatacaaaat
    43681 aaaattttta aaattaagca ataaaaaagg taggaggatt ttatgttttt caaagatatt
    43741 gaactaaatt caaaaaaaga gttagaccca tattttgatt tagtagatta tgaagcttgt
    43801 gagtactgtt ttagtacttt atatatgtgg caacatgttt ataagacagg atattatata
    43861 ggtgaagatt ttgccgtttt agttggggaa tacgaaggag atagcttctc aatattacca
    43921 cttgctaaaa aagataaact tccagaagtt gtagattttg tccttgaata tttttctaaa
    43981 aataataaaa aaatatactt aagaggtatt actactgaag tagtagagtt tttaaaagaa
    44041 aaatatccag gtagatttga gtatatagaa gaaagagatt tatttgacta tatttatgat
    44101 gcagaaagtt taagaactct agctggtaaa aagaatcaaa agaagagaaa ccatataaac
    44161 tatttcttaa aagagtatgc aggtagatat gaagctaaat tattagataa agaaaacttt
    44221 gatgagtgtt tagtactaat gaaggaatgg gaaagtaata aggaagaaaa taatgaattt
    44281 gatgaaagta tggatgatga attaataggt atcaaaaaga tatttaacca ttatgacata
    44341 ttaaaagata aggtaaaagt gtttggtgtt tatgtagatg gaaaattaga agcttttagt
    44401 ataggagagc ttttaaatcc aaatatggca ttgattcata tagaaaaagc taatcctgat
    44461 ataagaggtc tgtatccatt tataaatcaa caatttttgg taagtgaatt taaggacgtt
    44521 gagtttgtaa atagagaaga agatttaggt attgaaggat taagaaaagc taaactttct
    44581 tatcatcctt gcagatttgt tgaaaagtac agtgttaggg aggcttaata gactatatgg
    44641 agattaggta tgctaaagaa gaagagatag aaagtataaa agagatttgg agttattgtt
    44701 ttaacgatac ggagagtttt atgaagtact attttaatga taaatataaa tctgaaaata
    44761 ctgtagtagc tttagatgaa ggaaaaatta tttcttctct tcagctaaat cagtataagt
    44821 tattactaaa tagcaaggta tataatacat catatgtagt aggagtttct acacttccag
    44881 agggaagagg agctggatat atgaacaaag taatgaaatt tactttaaac gaattgtata
    44941 aaaaagggca attagtttct atattgatgc ctattgacta tagactttat agaagatttg
    45001 gatatgagca ttgttacgac cagattgaat atactattaa cacagatgat ttaaaaaatt
    45061 ttaagtcaag tggaaaaatg ataaagtcta atttatcaca aattgatgat ttgatacaaa
    45121 tagatagaac ttttttaaat gaggttaatg gtaatgtgtt aaaagatgaa cattattatg
    45181 aaaacttatt taaagagatt caaagtgaag atggattttt atacattcat gaaggaaatg
    45241 aaaaagatgg atatatagtt tattttcttc aggaagataa aatgtttgtc agagagttat
    45301 tttataaaaa tatagatgcc cttaaatcaa tgcttaaatt tatatataat cacaatactc
    45361 aatgtaagat agttactata tctactccta caatagataa gataagattt atattagaca
    45421 accctaaaga tagtgatata aaaataaaac cttttatgat gggaagagtt ataaatgtaa
    45481 agaagtttat tgaagatata gatattgaga atgatattaa tagctcattt aatttattaa
    45541 tagaagacaa gtttatagat gaaaataatg gtctatttaa aatttctata cagaataaga
    45601 aggtatctgt agagcagtta gataaaaaag gtgcagaaaa gcctcaagaa gattttgata
    45661 ttaaattaga tataaatacc ttaacacagt tatcattttc ttatatagat gtaaatgaag
    45721 ctattttctt aaatgatata aaagatgttt cagaagaaac actagaaaca cttaattgta
    45781 ttttttctaa aaaaaataac tatataaatg aatatatata ggtagagtac gttaaaagat
    45841 tttaaaaatc ttttgacgta tttttttgtt tagataacaa tttatcttgt ttaaaaattt
    45901 tctatttgaa aataatctaa ataatatact tttatatggg agtgattata attcaaataa
    45961 gaagaccatt attaattata ttaatgtttg tggtagctat atcatttatc attacaaata
    46021 acacaaaaaa cgacgaagaa cttaatgata agataataac tatacaagga gttgtcaaag
    46081 gaaaaattga aaagaaaaga tacaatcagt acaaggtagg ggtttttcta ataaatgatt
    46141 atacaaaaaa taaaaatttg aagattggtc agaaagttaa tattacaggt aaattcaaaa
    46201 gtttagataa aatgaagtat gatgattttg attatggaag gtatataaaa agtactggat
    46261 ataaaggtat agtgtatata aataactata aaattattga taaaaataaa ctttactctt
    46321 taatagggga aataaagttt tatattagta aaacttatag gtacttatat aagaaaaact
    46381 cagattttat aaattctata ctattagcag aagttgaaaa tttgactgag gaacaaaaag
    46441 aaatttttac tagaactgga actagtcatg taatatctat atcaggtctt catacaggaa
    46501 tattatgtgt aattatatcc tttctattaa gaggtataaa taaattgtat aaattattaa
    46561 tactgtcgat ttttataact ttatattgta taatggtagg tgcgtctcca tccataatta
    46621 ggtctatagc atttgttatg attttttatt tatcaatatt tattgataga aagaaagatg
    46681 gaatatcggc attgtctcta attgggataa ttttaattat gaataacccc tatgttatat
    46741 ataatgtaag ttttcaattg tcttttttag ctacactttc tatattaata ttctataata
    46801 aaataaatag tattataaaa ttaagtatgg tatcattgac aatatcatca aatatattaa
    46861 ctttacctat aatttattat acatttaaag gtataccatt gctttcaatt ataggaaatt
    46921 taattatagt accatttgtg ggagtaataa tgtatttaag tattgcaagt ttaatcgtat
    46981 ttaaagtaag tgtagtaata gctaaaatta tatctttttt taatagtaca tttatagaaa
    47041 gcatattttt tttactagaa aaaatcagca atttaagttt tgcatacatt aatatagaaa
    47101 atcctaaatt ttatattgtt gttatttatt acataggagt gtttttttac atattttaca
    47161 tagaaggaaa agagataaag gagcaagaga atgaattaca aggatattat aaggaatgta
    47221 aaagagaaaa actttgaaaa aatgtatctt ttttatggaa gagagtatta tttaattgag
    47281 aatgcaataa aagcatttaa agatagtcta aacgagggaa tgcttgattt taacttagat
    47341 ataatagatg ggaaggaaat agtcttaaat cagcttataa gctctataga aacacttcca
    47401 tttatggatg atagaaagat agtaataata aaagactttg aactattaaa aggaaagaaa
    47461 aagaatttta cagatagtga tgagaaatac ttaatagagc atttagacaa tattccagac
    47521 accacaacta tagtttttgt tgtatatgga gatgtagaca aaagaaaatc attagttaag
    47581 aaaataggaa acaatggaat tgtttttgat tgtgataagc tttctgatat ggatttgttt
    47641 aaatggataa aaaaatcttt tgctttaaat gatgttataa tagataattc tcaaatcatg
    47701 tattttattg aacaagaagg atacagagat aagagtagtg aaaagacatt atctgattta
    47761 gaaaatgaaa taaataaaat aagttcattt gttggtaaag ggaataatgt aaccaatgat
    47821 gtaattgata aattatctca aaaaaaagtt gagaatgata tattcaaatt aatcgattat
    47881 attggagaac aaaatgcttc taatgcaatg aaaatattaa atgatatgat acaagaaggc
    47941 gaatctgtat taggtatatt ttctatgata gcaagacaat ttaaaataat tatgcaagta
    48001 agacagttac aacttgatgg atattcaaca aaacttatag ctgataaatt aaaaatgcat
    48061 caatttgttg taggaaaagc attaaagcaa actaaaaatt tttctgatga tataattgtg
    48121 gaaatattaa actatatatt agaaagtgat tataaaataa agacaggtct tataagagat
    48181 actttagcag ttgaaatgtt ggttagtaga tactgtaaaa gagaagcaat ttaaaaaatc
    48241 tatatattaa taaaaaataa atagcaagat atgttatagt tcagagtaga tgtaagctaa
    48301 attaagtttg atatacaatc aactataata tgtctaacta tttatttttt attgtataaa
    48361 tttacaaaat aaaaaacccc tacatagggg ttattatata taagaaatat aaactggtaa
    48421 ttaagcgttc ataccgttta atttttgagc taatttagct acttttctag ctgcagcatt
    48481 cttatgtata gttcctttag aagctacttg gtatattctt ttttgagcgt attggaactt
    48541 agcaacagca tcctctctgt ttccagctgc aacagcatct tcgaatcttc ttattgcagt
    48601 ttttatttga gattttctaa ctctatttaa agcagttttc ttttcgataa cacttattct
    48661 tttcttagct gattttatat ttgccaccgt gttcacctcc ctgtattttt ttatcatatt
    48721 catcgtcaac atattagatt ttaacagaaa taaatctaaa aatcaaggat tattatttat
    48781 atattttaat aatgtttttt attttgattt tttagactgt aaattgtgta taaataattt
    48841 gcaatatctt gtttttaaat tggtatattt tgtgttttaa atattttgac atatataaat
    48901 taatatttta tttttgtaac aaatattttg agataataca aactattaac atacattttg
    48961 atagtatttc caataattat aagataatac aagaaattac tcatttttgt aaatttaatg
    49021 aaaaatataa tataaaagac aggaagaaaa tcttcctgtt tttttatact attttcttta
    49081 atgttcaatt atgaatgatg atataattga gatagtaaag gagtgaaacc tgtggctaaa
    49141 aaagttagaa taggagacaa actggtcgaa aaaggatata taacagaaga acagcttaaa
    49201 tgggcactat cagaacaaaa aaacagtgga aaaagactag gagaatttct agtacaagaa
    49261 gggcttatag atagtaactt actaataagt gtattaaaag aactcttgga tatagaaagt
    49321 atatttttag aagggacaga aatagacact ttagctacaa aaatggttcc agaaaatata
    49381 tgcaaaagat atactgtatt tccatttaaa attgatggaa ataaaatatg tctagccatg
    49441 tcagacccac aagatagaga agcagttcaa gatgtaaggc gtatgtctgg taaagacgta
    49501 gagatattta tatcaagtac agaagatata aacaaagcaa taggtcatgc ttatgcacat
    49561 tcagaaataa ataaggcaat gactgagtac aacaaaaata gaactggtgg agtaagagaa
    49621 acagtaatac ttgaagaaga tgtaaatgct gctccaatag tacgattagt aaataacata
    49681 ctagaaaatg ctgttagaat ggaagcaagt gatatacata tagaacaaag tgaaaattac
    49741 atgcgtgtta ggtttaggat agatggaatg ttaagagaat atatgaggat gaactcagca
    49801 ccatataagg cagtaatcag ccgtatcaag ataatgtcag atataaatat atctgaaaag
    49861 agaataccac aggatggtag aatctattta aaagtagata ataaacccat agattttagg
    49921 gtttctacaa tgccaactaa cagggatgaa aagatagcta tgagagttct tgataagagt
    49981 aattttatgg ttagtaaaga agtactagga atagacgaac atggctctaa gatatatgat
    50041 gaattgataa acactcctta tggtcttata ttggttgttg gccctactgg aagtggtaaa
    50101 accactacat tgtattcaat gttaaatcaa ctaaatacag aaaatagaaa tctattaaca
    50161 atagaagacc ctatagagta tgaattacct ggtgtaaatc aatctcaaat aaatgaaaag
    50221 gcagggctta ctttcgccag cggacttaga gcttttatgc gtcaagaccc agatataata
    50281 atggttggag agataagaga tactgagaca gcagaaatag caattagagc ttctcttaca
    50341 ggacatttag ttttaagtac attacatgca aatacagcag ttggagcaat ttcacgtctt
    50401 ttagatatgg atgtggaaag ttttttaata acttcatctg ttttaggtgt aatatctcaa
    50461 agacttacac gaaaaatatg tgagcattgt aaggtttcat atgaagcaga tattggagaa
    50521 aaaaaggctc ttggtattga tgtaaatgaa tcagtaacta tttatagagg aaaaggttgt
    50581 gaaaggtgta ataatactgg atataaagga cgtctaggta tatttgaaat gcttgaaatt
    50641 actccagaaa taaaagagtt aatagattca tctgcaaatc aaagagaaat tttaaagatg
    50701 gctagaaaac aaggtatggt tagcttaaaa gaggatatag ttaaaaaagt tttaaatgga
    50761 aagacaacag tagaagaaat gattagaata attttgatga ctgattaaag gatgatatta
    50821 tgaaaagttt taaatacaca gtaataaaag aggacggaaa aaagcaaact gatgtgattg
    50881 aagccaacga ttttaatgaa gctagaaatc ttcttagaaa gagaaatctt agagttattg
    50941 aaatcaaaga aagcaaaaat aaaaatataa gattatctag tagaaagaga aaaaaagact
    51001 taggagctga ccagataagc cacttttgta gacagtttgc tattatagta tcttctggta
    51061 taaatagtat ttctggatta gaaacattag ctagaaggtc aactaacatt acattaagag
    51121 aagaaattaa tcgtatagtg gcagaaataa aagtaggttc tactattgca gattcaatgc
    51181 tttcatcaaa atcaaagttt ccaaagttac ttggtgctat ggtagctaca ggtgaagcta
    51241 caggtaaatt agatgaagta ttaaaaagta tggcttcatt ttatgcaagt gaacacaggg
    51301 ttaaacaaaa gcttagaaat gctgcaacat atccattaat agttttgatt tcttcattta
    51361 taatgatttt tatatttaca acatttatgg tgcctaagat gattaattca attacaacag
    51421 taggagcaac tcttccactt ataacaagaa ttgttatggg gtttggtatg tttatgaaga
    51481 agttttggat aatagtactt ttagttatta tattatttat ctatcagttt aaaaaatatc
    51541 taaaaacgtc agttggaagg gctcataaag atagagttat aaataagata cctgttttag
    51601 gaaaaggaat aaattgtatg gtagctacac gattttcaag agcattgtat ctatttgtat
    51661 caacaggata cccattagtt caagggcttg attatattat agatagtgta aataacacca
    51721 tggcagagaa gattttagca tcagctaaag atggaataac aagaggagaa ggcttagcag
    51781 aaaatttaga gagatatacg tattttgact ctgtgttggt acagatgata gctatagggg
    51841 agcagacagg ggaattagag aatataagta gacagatggc agaattttat gagtatgaat
    51901 ccgagattta tttaaatagg atggcctcaa tgatagagcc tgttttaata attgcagttg
    51961 gtattatagt tgcgatactg gttgtatcaa tattcatgcc aatgcttagt atatatgatg
    52021 ccatgtagga gggaaaggac aaatgaacaa ggtttatgta tcatattatg gcgattctat
    52081 ttccatagtt gagggcagat ataaacacga taaggataag ttttatgtaa aaaattttaa
    52141 tgtgttttca atagaggata ttgcacaaga tttttctaag gaaaagtatg ctctattgag
    52201 atacgcatta gaaaatgtta agttaaaatc aagacatgta gttttttgtt taaatacaag
    52261 agatgtaatt ttaaaacccc aaaaacttcc taatatggac aaaaaggatt tagacggatt
    52321 tatgaagcta gagatggacg aaatgatggc tttggagtca gatgaatatg tattttcgta
    52381 tgaagtatct agtgaaacac ctgataattc agatggcgat gaatcaagtt taaatcttat
    52441 tattggagct atacaaaagg aagaggtaaa tgcaattgta gagataatgc atgaatttga
    52501 tttagtatta gatagaatag atacattatc aacagcttac ttaagaatgc ttaaaaattt
    52561 agactacaat gatataatgg taaccaatat aagtgacaat agcacaatta taaatatata
    52621 taagaaagat actttattta ttagtgataa tatacctata aagataactg ctaaagatat
    52681 ggacatgcaa ttattaaatg tagtagaaga atcaaaaggt cttatgaatt actattcgtc
    52741 aagaaacttt ggtaaggtta cggatactat attaatatta ggaaaaagat attccaataa
    52801 attaatttat gaaactttta gctctgcatt ttcaagctat gtttctcaag gccttactga
    52861 gataatggat atatctgata tgataactgg agatatagat gaagatgata taaattcaat
    52921 tgtagagctt ttaggaagta tgatagaacc taaagggaaa agagattttg aaaatataaa
    52981 ctttttacca atggatatac ttagaaaaca gataaaagct aaacaaatga aaaacatact
    53041 gaaaattgct ccaatagtta ttttgattct tgctatacct tatttatgtt taattttttc
    53101 aaataattta gcaaataagg aacttgaaaa tgttaatggt gaaataagaa atattgaatc
    53161 tgcatattat cagattggaa atatagaaaa aatgatacag agtaaaagcg aagaaataaa
    53221 ggtatatgat atgttaattg ggaaaaaggt aaagtgggaa aatttattgg atgatataga
    53281 taaaaatact ccaagtaaag ttgaactaac aagtttatca acaacttatc aaaatcttgg
    53341 aactaataat aaagctgata attcaaaaag taataagact acaacagata aatcaagtaa
    53401 caatgaaaca aaatcaagta cgaaaagtga tagtaatgga gataaaacag ataatgattt
    53461 aaatgaagat aagactacaa atgtgtcaga agcattaact ggaaatagtg agactaatag
    53521 taataacaca gataaagatg ataaaactcc attgtatgat aagataccaa atgttataaa
    53581 tatagaagga aatgctaaag attcctctta tgtaggtcaa tttttatata aattaaaggg
    53641 attatactat ttcaaggatg ttaaattaca tagcataaaa agtaatgcag aagattctaa
    53701 ctatacattt agtatgacat tatacctgaa agaaggtgta ttaactaatg aataaagata
    53761 tatttaaaaa agatataaaa gatatattta aaatggaagt tagtctaaaa gggattctta
    53821 taaaggttat aattttatta gctattttat catatggtta ttttggactt taccctcaat
    53881 atcagaaata tattgctaca aaaaattctg taaaacaggc tactgaaaaa ttaaatatat
    53941 ataaagagaa aactgcactt atgccaaaat atgaaaaaca acttgaagaa gttgaaagtg
    54001 aattaaaaga aaaaagcaaa aatcttttat atgatatgca agatggtctt tttttaatag
    54061 gtttagataa aaaaatgaag gcttataata ttgacttaac cagttatgac gttggaaatg
    54121 ttaaagaata cgaacatttt tatggtatat caacaacaat aagtgttaga ggtgattata
    54181 gaaatgtcaa aaaattaatg gcttatttag aagaacaaaa aaatgttact caaatactag
    54241 attatacaat gacttcatat atagaaccag aaaaagaaga ggaagaaaca acaaacaata
    54301 aggatttaat taaaaatgtg aacataaata aagatacaaa aatatactgg gtggaaggcg
    54361 aaaataagtg gcatttatat aaggattgtc cattgataaa agagggagag attctaaaaa
    54421 atgacaaact tttagatagg tctactaatt atctatgtaa tacttgtgta cttagagctg
    54481 caacagaaaa agaagcaaaa aaagaagtcg tagctccaaa ggcagaaggt gtagtagatg
    54541 ctacatttaa atttataatg tacactaaag agaatactac aatgatactt gatacagata
    54601 atccatcttc atggagacca ggaaaatata atccatttaa gtctagtgcg aaataaagct
    54661 aagtaagctt taaagatagg tgatgagttt gtacaaaaat aatgaaaaag gtcttacttt
    54721 attagaagta ataatagctg tttttatact gacaatagtt ttaagtattt cttataaagt
    54781 gttcaatggt ataacatcag cagtaaaaaa gcaacagatt attacagatg ctcaagtaaa
    54841 tattaatcta attaataagt atctaaatag agatttggaa aactgtaaag aactaactaa
    54901 aactggttca ggtaataatt atgaatacaa tatagagatg ccagataatg ttgtaaaata
    54961 tgaagtttct atagaaacta aaaaaaatac agaggtatat tctgtaacga gaatccaaaa
    55021 caatacaatt gatacagaaa atgaagttag agaagagata atctataatc aaccactagt
    55081 tcaaaacaat aaagaaatga aggaaacacc atttaaaata gaaaagcaaa ctggtaaatc
    55141 tatttatact gtaagtatat actataatga atcagtgcaa gaaagtcata aaaatagcaa
    55201 tttaaataac aaaacttata catttgatgt tatgtcaaga ataggataat aagaatttat
    55261 taaaaaataa gtaggttgat aaaatatgag taaaaagaat agtgaaagag gattttcctt
    55321 aattgaagtg ttagtagcta tggctattat gggaattgta ctatttgcat tttttaatat
    55381 tatcaatact aataacaaag caaacactaa aaatgacaca gatataactt ccttaaacta
    55441 tgtccaaagt gaaatagaaa atctaagaga aaagataaaa agtggagaat ttgattttga
    55501 tagtttagat aaactagaag atggaactgt cgtatatgaa aaattaatag ataaatcaaa
    55561 aaaagttgta tatgataaag ttcttagtga aggtgatgtg agcttatatg atactccata
    55621 tgaaaagatt acaacaataa aagatgaaga tggtaattta atcgacaaag gaaatattac
    55681 aaataagata aagactattg tagaagataa aagtggtcag atatataaaa tagctgtaac
    55741 tgggaaaagc atgaatgact attcaagtaa aaaagaggtt aaaattgtaa ctgaaatatt
    55801 taaagataaa taattttact tgggggtgag attttgagga agtggaataa atttaaaagt
    55861 gaaagagggg cagctttagt tttagttttg gttgtagtag cattgctttc tattgttgga
    55921 ttgatatttt caaatcagat agctaataga ataaaatcta caaagactac taatgaaggt
    55981 atacaagcaa agtatttagc agagacatgt gtggaaaata gtattgataa agcatatgaa
    56041 aaattgtatg atgagcttga gaaaatggat aatgagttta aaagtgaaaa tcaagaaaaa
    56101 tccatatcta ggtcaaaatt aagagatata tcagatgaag attttaataa tcaagatgag
    56161 gaaaatattg aagcagaaag acttggatat atgaataata taaatttcta tttaaataaa
    56221 gcttcttcag acttggaaaa agctagtatg gaattgaaaa agctatatga tttatatatg
    56281 ttggactata gagacattga atatgtagat gcaaatatta tttcacatag agattctatc
    56341 ttagaaattt gcaagaatta tacttctgga gatattagta aaataaatga atatattctg
    56401 aaagaagata tagactcaac tacattgatt gaggcaaagt tagtgaataa tgatattctt
    56461 ttaaaaatgt ttttagaaga aaataaaatt gaaaatgaac atttaaattc agccttttca
    56521 catacttata aggcattaga taacatttct ttggcgatgc aaaatatgat tgagtataga
    56581 catacgtttc atatagatga gccaaaagta gaagtatcta atgggattcc agattctcaa
    56641 caatattatg aactaataca aaatcctata ataaatagta tggagtatat ctggaatagt
    56701 aaatgggata cattagaaaa actattggaa attttaccaa atcaaactca aggatttaat
    56761 tctttaagag ttcatttgag aaataatgta agaaaatttg agaagttaag cgataatata
    56821 tctagtggta aaaaaaatac agcaaaaaat ttcttaaagt ataaagagtt attgtatgaa
    56881 atatcagacc aatgtaatca actaaaaagt atgtcttatg agaaaatacc tgttaaatat
    56941 gataacatgg ctttgataac aacttttgac tatatacaaa atgagctttt agcagagata
    57001 aaatgcagat taaaagaatt aaaaccacaa gaaattgata aaacagaagg tattactata
    57061 aaaatacctt tttataaggc tgactacgac atgacaaaag aaggatggcc taaattaaaa
    57121 gaaaatggtt caggggcgga gttaagctta atggtaactg gtgataaaga tggaataaaa
    57181 gaagtagaag ttacagatgg taaaaaaaat attattggtt taggtgttga agaaaattca
    57241 aattcaaagt ataaggttga cgccattgta aactttaatc taaatataga tacaaatgta
    57301 gttggaaatt atgatataaa agataaaatt ttgattaatc atgatataag ttcatacaaa
    57361 aaagtaaact aaatataaga agcaacttag tataaataaa taataaaata attttattat
    57421 ttactactaa aaaaataagt aaactaatag aagatatgga gagtaaatat tatgtatatt
    57481 tatgatttat tagagcaagg tataagacta aacgcatcag atatacacat aacagttgga
    57541 acaaatcctg tagctagagt aaaaggtgga tttgtaaaac taagtgaaca aatattgaca
    57601 tcagaagtaa caatgcaaat ggcaaaagac atagcagggg aatctatgtt taaagtaata
    57661 gaagaacatg gagaagctga tttttcagct tctttaaaaa caggagaaag atttagggta
    57721 aatgcatata ggcaaaaagg aaattacgca atagcaataa ggactataac agcagaaatt
    57781 ccaacatttg aaaaattagg ccttccagag agtataaaat cttttactga aaagcataaa
    57841 ggattagttt tagttacagg tccaacagga agtggtaaaa gtacaacact tgcaagtatg
    57901 ataaatataa taaatgaaaa acaacaaaaa catataatta cacttgaaga cccgatagaa
    57961 tatgtacatc atcataaaca aagtttagta aatcaaagag aagtaggaac tgatacagaa
    58021 agttttcatt cagcccttag agctattttg cgtcaggacc cagatgtaat actaatagga
    58081 gagatgagag accctgaaac tgtttcaata gcattaacag cagcagaaac aggtcattta
    58141 gtattttcaa cactacatac agtgggggca gctaagacaa ttgatagaat agtagacatg
    58201 tttcaaccat cccaacagca acaaataaaa acacagttat ctacagtttg tgaaggtgtg
    58261 gtatcacagc agttacttcc tacagcagat gggaaaggca gaatagcagc aattgaattg
    58321 atgtttgcta ctccagcaat aaaaaacctg ataagggaag gcaaaacata tcaaattcca
    58381 aacatgatac aaactggagt taaagtaggt atgaaaacta tggaccaaga tttaatggaa
    58441 ctttataaaa atggaaagat tacaaaagat atggcactta gtaggtgtac tgaccaagag
    58501 tttatgacaa gaatgatagg tggagtaaac tacaatggat attataatcg ttaatctata
    58561 tgtatttatg gtgggtatag tgtttggaag tttctttaac gtctgtattt ttaggattcc
    58621 agaaggtata tctatttcta gacctccttc tcattgtatg agttgtaata ctagactaaa
    58681 gccaatagac ttaataccag tgttaagcta tttaatgagt ggcagaaagt gtagatattg
    58741 ttatgagaaa atttctagta gatatgctat agtggaatta attacaggac ttttattttt
    58801 aacagtattt atgttatatg gaatatctac atcaactatt tattatttgg ttcttgtgtc
    58861 tttactgatt ataattacat ttatagatat tgaccacttt ataataccag ataaaatatt
    58921 ggtttttgga gctatatttt ctatgatttt taacctttta tttaaagaaa ttccagttaa
    58981 ggattcaatt ctaggtgttt ttatttgtgg aggaagtgtc tggattatag ttcttttgat
    59041 tgaatttgta ataaaaaaag agtgtatggg tggaggagat atcaaactat ttgcaatgct
    59101 aggtttttac atgggtgtta aaaatggtct tttgacagcc ttactaagcg tttatgtggg
    59161 agcagtctat ggaatctgtg taataattat aagtagaata aaaggaaagg aatataattc
    59221 tgttatacca tatggacctt ttatatctat tggagcatta ataacaatct tatgtggaaa
    59281 gcaattactt gaactttatt tttctatggt tatatagatg atagtcaagt taaataaagt
    59341 tttaatttaa aaaaatgaat taaagtattt aataaggaca atattattat taaccctatt
    59401 actaaagtgc tacaaactat ggagtatata ataataattt ccttattttt tgcacatttg
    59461 ataaataaat ctctatgtgt tttttgtgat agagaaaaga aaaatttata caatacgttt
    59521 tttatttaca taataactgt agttttatct gtattaatat atctaaaatt tgggattagt
    59581 gtagaatgtg tacaatatat ggttttaatt ccatttttaa taattatatc cattgtagat
    59641 tactacacaa tatatgtata tgatataaca atagttagtg gtataatagt tcaaggtata
    59701 atttttttgg tctttttcaa tatagttcaa tttgattata taaatcatat atttggacta
    59761 ttgataggct ttattatacc ttatattatt gctaaactaa caaaaggatt aggctatgga
    59821 gatgtaggtc tctatagctt atgttgcttt gcattgggaa ataattatgg gttttatgtg
    59881 atagttttat catttatttt agcgtttttg ttttttatta ttttatacat aactaaaata
    59941 tttaaagatg tagatataag aaagcaaatt ccttttacac cttttatttc cttgtcaaca
    60001 attttaataa tatttacaga gtataatata tttaattttt attataattt gttatacaaa
    60061 tttatataac aggaggtaag aaatgtacgt agtagtaggg ttaggtaatc caggaaagaa
    60121 gtatgagaag actagacata acgttggatt tgatgttata gatattcttg ctaaagaata
    60181 caatattagt gttactaaaa taaagcataa agctttgatt ggtgaaggga gagtaggtac
    60241 tgaaaaagta ttattagtta aaccacaaac ttatatgaat ttaagtggag aaacattaat
    60301 agatatatat aaatattata aggttgattt aagtaatata gtagtagtat atgatgatat
    60361 agatttagaa gttggaaaga tacgtataag aaaaaaagga agtggaggaa ctcataatgg
    60421 catgaaatct ataactaagt gcctaggttc aaatgacttt ccaagagtga gagtaggtgt
    60481 atctaaacca gaagctggtc aagacttagc agactttgta ctttctagat ttagaaaaga
    60541 agaatctgat aacataaatg aagcattaga aaaagcggca gatgctattg actcaataat
    60601 aagagaaaat atagatatgt ctatgaacaa atataatgga tagtgagagg gagatttaaa
    60661 tgaatgatgt ttttttatat cctttgcaaa attcaaaaga gtataaagat ataataaact
    60721 gtataaaaaa tacaaaaggc tcattattgg ttaatggact tttaccagta caaaaacctc
    60781 atatatcgta ttctatattt aatgatttat cacgacaaat gatttttata acaagtagtg
    60841 atttagaagc aaagaaagta tacgaagatt taagttttta tatggaagat aaagttgaat
    60901 atttaggttt tcaagatatt tatttttatc acttggatgc aaaggacaga aacgaagaag
    60961 cgaagaaatt aaaagtattg ttaaaactag caaataaaga aaaaatcatt ttagtaactt
    61021 ctattgaggc agttttaaga aaatacatac caaaacaagt tttgctcgat agtgtatctc
    61081 attataaggt gggagatagc ttagacttag aaaagttaac tgagaaatta gtttcattgg
    61141 gatatgaaag agtttcaaaa atagaggggt ttggtcaatt tagtataaga ggtggaatta
    61201 ttgatgtatt ttcacttgaa tatacaaatc caattcgtat ggaattattt gatgatgaga
    61261 tagattccat acgaactttt gacgtatatt cacaaaaatc aattgataaa ttgcaacaat
    61321 tctctataac tccatctagg gaatttattt atcccgaaaa aactacagat gcattagtta
    61381 aattaaaaaa agaaacaact aaaaatactg atgaaggtac atttcaaaat atagattata
    61441 tatcaagtaa gacttatttt gaaggtgtag agaactatat agattatatt tatccagaag
    61501 aaaacaaaag tatatttact tatttagcag atgatgcaat agtatttatt aatgatataa
    61561 cgagacttaa agaaagatgc gaaaattata taaatgagtt tagagaaaat tataaattaa
    61621 atcttgaaag aggtctggct attaaaaacc aaggtaaatt gttatatcac tatacagatt
    61681 tagagtactt agtaaaagac aagtctgtgg tattaaactc gctattgcca aagtctataa
    61741 ataacttttc tataaaatct ataataaatt ttgaaagtag agaagttcct acatttaatg
    61801 gaaaggtaga tttgcttgta gaagaattaa atcggctgaa atataatgga tacaaaataa
    61861 ttttagcaac aaatacctta gaaagagcaa ataaattagg aaaagattta ttggacaaag
    61921 gcttagaaac gaccatttct aaagatagag atattgaaat taaatcttca caagttataa
    61981 ttgtacctgc acacataaac agtggttttc agtataaatc tataaagttt gttgttataa
    62041 cagataacga aatgataggt gtttataaaa gagcgtctaa gactagcaat aaaaaagtta
    62101 aaaagggaaa gaaaatagaa tcctttttag atttaagtgt tggagattat gtagtccatg
    62161 aaaatagtgg tgtaggtaga tacacaggaa ttgaacaaat tacagtcaat gctattaaaa
    62221 aagattatat gaaaatagta tatcaaggtg gagataatct atatgtgcca atagaccaga
    62281 tggacaaagt acaaaaatat attggtgcag aagtagaaaa agttaagtta aataagcttg
    62341 gaacaaatga gtggacgaaa gcaaaagcaa aagttaaaaa agaaattgaa gatatgacaa
    62401 aagacttgat tgagctttat gcaaaacgtg aaaaaataca agggtataag ttttcaaaag
    62461 atacaccttg gcaggcagag tttgaatcgt tgtttccata tcaagaaaca gaagaccaat
    62521 taaaggctat agaagaaact aaaaaagata tggaatcaag taaggtaatg gataggctag
    62581 tatgtggaga tgttggttat ggaaaaacag aggtagctat tagaagtatt tttaaagctt
    62641 gtatggacca aaaacaagtt gctgtattgg ttccaacaac aatattggcc caacaacatt
    62701 ataatacatt caaagagagg tttgaaaatt atcctttgag agtagaagtt ttaagtaggt
    62761 ttaaaacacc aaaacaacaa aaacagatta ttgaagatgc taaaaaagga ttagtagata
    62821 ttttaattgg aacacataga ataatatcca aagatataaa tttaccaaac ttaggtcttg
    62881 tagtcattga tgaagaacaa agatttggag taaaacataa agaagcttta aagaaaatta
    62941 aatctacagt agatgtactt acactttcag caactcctat accaagaaca ttacatatgt
    63001 ctttaagtgg aataagagac atgagtgtta tagaagaacc tccacaagaa agacatcctg
    63061 taataacata tgttacagag agtaaggaaa gcgtaattca agatgagata gagagagaat
    63121 taagtagagg tggacaggta ttttttgtat acaatagagt tgaacacatt gaagaaatgg
    63181 caagtatgat tcaaaaactc gtaccagatg ctagagtggc tgttgcacat ggaagaatga
    63241 cttctaaatc attagaaaat ataatcctag gatttttaaa taaagattat gatgtactag
    63301 tctgtactac aataattgaa actggtatgg acatatcaaa tgcaaataca atgattatat
    63361 atgatgcaga taaaatggga ttggctcaac tttaccaatt gagaggtagg gttggaagaa
    63421 gttcaagaca aggatatgca tatcttttgt atgaaaaaga taaaacttta agtgagatag
    63481 cggagaagag attaaaagct atcagagaat ttacagagtt tggttctggt tttaaaatag
    63541 caatgagaga ccttgaaata agaggagcag gaaatatttt aggttctcaa caacatggtc
    63601 atatggcagt tataggttat gatttgtacg ttaaaatgct taatgatgca attaaaaaag
    63661 tcaaaggtga gcctattgtg gaggaaattg atgttgaaat agatttaagt gtaaatgcat
    63721 acattccaga taattatatc aaagatgagt tgattaaaat tgaaatgtat aagaaaatag
    63781 cttctattga aaacaaagaa gacatgttgg atatacaaga agaacttgag gatagattct
    63841 ctgatatacc taaaccagtc cagacacttc ttacaatagc ttatataaaa tcgttatgta
    63901 agatattaaa aatagaaaag ataagacaat taaaagatga aatattatta gttccaataa
    63961 caaagtatag aactaaacag aaaataggtt ataatatagt tacagaatta gaagaattat
    64021 tagaaaagat gtgcaaggta aaataacttg taaatttaag aagggatgtt ttaaatttga
    64081 aaaaagtaat aacattggta atagctatga ttttggtagt atctgtgact gcttgcagtt
    64141 ctagtaaagg agaaactgtg gcaacagttg aaggtacaaa gatatcatca gatgaattta
    64201 aaaaaactat agctctttat aaagattcta tggaacaaac ttatggaaaa gatatatggg
    64261 ataaggaagt tgaaaagggt gtaaaataca aggacaagtt taaagattta attcttgacc
    64321 aacttataac tacagaagta atatattctc aagctaaaaa agataactta cttcctaaaa
    64381 aagaggatgt tgaaaaaagt tttaaagaat taaaagacgc tatgggtaaa gatgaaaaat
    64441 ataaagaaca acttaagaaa ttaggtatag atgatgagtt tttaagagac caacaagaga
    64501 aagatttagc aatgcaaaac tatcaaagta actttgctaa aaagactaaa atatcagatg
    64561 aagaaatgaa aaaatactat gatacacata aagatgaatt taaaaaagat gaggtagaag
    64621 cttctcatat tttattgaaa acagtagatg ataataacaa gccactttca gataaggaaa
    64681 aagctgaagc taagaaaaag gctgaagagg ctcttaaaga agttaaatca ggtgaggatt
    64741 ttgcaaaagt agcaaaaaaa tattcacaag atacttcagc aagtgatggt ggtaaattag
    64801 gattcttttc aaggggtcaa atggttgctg aatttgaaga tgctgctttt tctatgaaaa
    64861 agggtgaagt atctgattta gttgaaactc aatatggata ccacataatt aaagtgacag
    64921 acagaataaa tgagcaaaca tcatttgaag atgctaaaga aactataaaa gaccaactgt
    64981 tgaaaaataa atatcaagaa caaatagaaa aattaactaa agaagctaag gtagaaaaag
    65041 atgaaaaagt aataaataaa atcacaatct aagacttaaa aaaagagtaa tatgcttaaa
    65101 aaagctatat ctggataaga tatagctttt tttgtatatt tttcttaaca atggtaaaaa
    65161 taaacttaaa gtaatttatg gagggattaa aaaatatgaa agcaacaggt atagttagaa
    65221 gaatagatga tcttggaagg gtagttatcc caaaagagat aagaaagaca ttaagaatta
    65281 gagaaggaga ccctttagag atattcacag caaaagatgg agaagtcata cttaaaaaat
    65341 actctccaat aggtgaatta aatgaatttt cgcaagaata tgctgaaaca ttagctgaag
    65401 tactaggata tggagtgttg ataacagact tagattctat aatagctgtg tctaagcttc
    65461 ctaaaaaaga ttataaagaa aaaagtataa gtgatgagtt agaagcaata ataagtgaaa
    65521 gaacagtaaa atattcaaaa gataaaaaca ttttaccatt attcaaggaa gaccaaaaag
    65581 aatatactag tcaagttatc atgcctataa ttagtgcatc tggtgactgt ataggttcaa
    65641 ttgtagttgt ttcaaaggat aaagatacaa ttgcagaaag tgaagaaaaa tctttaaaaa
    65701 ttgctgctaa ctttttagga aaacaagttc aataatttta tcataaagac cttttacatg
    65761 aaggtctttt gaagtttttg tgtaaaatat tgaatatagc attaaaaata tggtatatta
    65821 aagtttgtta tataaacagt atggaggtta tgttatgaac aataacaaaa ataaagactc
    65881 ctttctaaaa ggagccctta tacttgggct agcaggtgta atcgtaaaaa taatgggtgg
    65941 attttttagg attccccttg gaaacatgat tggttcagaa ggaatgggat actatcaggc
    66001 tgcttatcct gtgtatactc tatttttaac attagctact gctggatttc caacagctgt
    66061 ggcaaaattg gtttcggaaa aagttgcaat tggaaatttt aaaggtgcaa ataagatatt
    66121 taaggtatca catacagttt tattcattac cggtataata tcattttgta tattattttt
    66181 tggagccgac tacatagtaa caaacgtaat gaaaaatcca ggtgcgttat actctatgaa
    66241 agccattgct ccagcattac tatttgttcc tgcaatgtct gcatatagag gatattttca
    66301 agggagacaa gatatgacta agattgctgt gtctcaagtt gcagagcaat tttttagagt
    66361 tgtattaggt cttactttgg cttacttgct tatgaagagt ctaggtcaga cttttggtgc
    66421 agcaggtgct atatcagggg ctacaatagg ttcaatagca tctatgcttt atttggtgtt
    66481 tgcttatatg ctagggagaa aagagcgtag agcagagata gatgcaagcc aaagatttaa
    66541 agatgaaaga gtgtcttata tttttaaaaa gcttttaact gttgccattc ctataacaat
    66601 aggagcatca gtaatgccac ttgtaaatat gatagataat gttattgtaa taagaagact
    66661 tatggaagca ggctttacat acaaagtggc aaattccatg tttggtcaat taacaggtat
    66721 ggcaatggcc acaataaatt taccagcagt cataacaact gcaatgagta tgagcttagt
    66781 tccagcaatt tctaaagcat atgcattagg aaataagtca aaagctagaa aagatactaa
    66841 gagtgcagtt aaggtaactt tacttatagt attgccttgt gcgtttggta tggcttcttt
    66901 agcaatacca ataatgggtc ttttatttcc acatgaacca tcttctgtag gaactatttt
    66961 gtttactctt actccatgtg tattattttt aggattaata cagacattga ctggtataat
    67021 tcagggaatg ggaaaaccaa tagtacctgt aattgcttta tgtgttggta tgctatgtaa
    67081 aattgtaata agttatactt taacaggtat accagatatt aatgtactgg gttcagcatt
    67141 tggtacagtt acagcatact ttgtggcagc catgattaac ttactatatg ttaaaaaaca
    67201 catgaatgta aacttttcta aaaaagaatt tataataaag ccatttataa cagttatgac
    67261 aatgtttata atggttaagt tgagttatgg tgctttagtt ggattcttag gaaacagcat
    67321 atctacaata attgcaatat gtgttggtgg aattgtatat gtagtagtaa tacttggaat
    67381 aggtggaatt aaaaaagaag agattctaac tatgccaaaa ggtgataaat tatataaatt
    67441 gttaaaaaaa gttaaactta taagataata taggaatata tatgcaaata aaggaaatac
    67501 tatacaaata gtaaatctcc ttatttgtat aataatataa aaataaagtg aaatttgcta
    67561 ataggagtga tgttatgggt aagataagta ttgtaggtct tggaccagga gactattctc
    67621 ttataagcca aggtgtgtta gaatctttaa taaatagccc taaagttttt tttagaacag
    67681 agaaacatcc aataattgat aaacttaaag aaactataca atacacttct ttagactact
    67741 tttatgaaaa agaggaaaat tttgataatg tttatttgaa aatatctgaa tttatcatag
    67801 aagaatcagc aaagggtgac ctagtgtatg ctgttcctgg tcatccaaga gttgcagaga
    67861 agactgtaag tataatagag agattagcca atgaaaagca catagcagta gaaatattgc
    67921 cttctatgag ctttgtagac gctatgttta actatttggc tatagaccca tctgagggat
    67981 ttaaactggt agatgctttt gaaatagaaa attcatatat agacttggat acaagtatga
    68041 taataactca ggtatatgat aaatttatag catctaatgt aaagttaaaa cttatggaac
    68101 attatgacta taatcaagaa gtatgtatag taaatggagc tggtgtcaaa gatttagaaa
    68161 gtaaaaagtt tataaagctt tgtgaattag acagaaatga aaactttttt gactatttaa
    68221 ctagcttata tatacccaaa agttctaaaa agatgtataa tacagtacat gacttagaaa
    68281 taatagttaa tacacttaga agtccatctg gatgtgaatg ggataaaaaa caaacacatc
    68341 aatcattaaa aaattctgtt atagaggaag catatgaact ttgtaatgca attgataata
    68401 atgatataga tgaaatggta gaagagttag gtgatgttct tttacaggtt atattccatt
    68461 gtcagatagg aaatgaggag ggctactttg atttaaaaga agtagtaaat ggcatatgta
    68521 aaaaattaat tcatagacat cctcatatat ttagtggtgc aaaattagat atgtctaagt
    68581 ttgagaaaac ttgggaagaa ttaaagaaag aagagaaagg cgaaagtact ataacagatg
    68641 gccttagaag gataccaaaa catttaccag ctcttatgaa ggctagtaaa gttcaacata
    68701 aagcagcact tgtcggcttt gattgggaca atgtagaaga tgtatttaaa aaaattgaag
    68761 aagaatatca ggaattactt gacgaacaca gggtcgggaa tataaaatac ataaaggaag
    68821 agctaggcga tttattattt tcgatagtaa atctagctag atttttagac atagactcag
    68881 gagaagcctt gaactgtact acagaaaaat tcataaatag atttgacttt atagaaaaga
    68941 gtgcaatgaa cttgaataaa aaattagaag acatgacact tgaagagatg gatgagtttt
    69001 ggaatcaggc taaaaaacaa taaaattgtg gaaggaaatt tgtcaaaaat ctagaacttt
    69061 tatcacaaag atagaagtct atattataaa catttttagg aggtaaatat cgtgaataaa
    69121 gctgaattag tatcaaagat ggcagaaaaa agtggattaa caaagaagga agcagaagct
    69181 gcgttaaacg catttatgag ttctgttcaa gatgcactag taaataatga aaaagttcaa
    69241 ttagttggat ttggaacatt tgagacaaga gaaagagctg ctagacaagg aagaaatcca
    69301 agagatccag agcaagttat agatatacca gcttctaaag caccagtttt caaagctgga
    69361 aaaggattaa aggatataat aaatggataa ttagaaatct tgtgaaaaag tgtggataaa
    69421 tttgccacac tttttctata gaaccaagga aggtgataat tatgagatta gataaatttt
    69481 taaaagtatc taggattata aaaagaagaa ctgttgctaa agatgcatgt gataaaggga
    69541 ttgtcactat aaatggaaaa gttgctaaat cttcttcaga ggtgaatatt ggagatacat
    69601 tagaaataca atttggagag aagaagatga agtttaagat aaatgaagta aaagagcatg
    69661 tattaaaaaa tgatgcaaaa gaaatgtacg aaattttaga ataaaattaa tagtcctcta
    69721 gtatattaat agtagtatta ttgaaatatt tactgggggg atattatgga acagaacata
    69781 actttgaaag atagatcaaa gctggttatt tcgggagtcg agcacatata ctcttttaat
    69841 gacaaaagag tagagctcaa aacttctgta ggcgagatgg taattgaagg cgaaaaccta
    69901 gatatgagca agctaagtat agacgaaaat ataattagca tagatggaac tataaattct
    69961 atggtatatg caaagcctaa aaagccacaa gagagtttct tgaaaaaggt atttagatag
    70021 atgatacctt ttactcaaga tgtaagcatt ttttatgcta ctatttatgg tggaatactc
    70081 ataggggtgt tgtttgattt ttatagaggg ctaagaggga attttaaatt catcaattat
    70141 tttgctataa tatttgatgt attgttttgg tttctagcta cggttataat attcgtaaca
    70201 ataaacctta cagaattttt tgatttaaga tattatcatt ttgtggcttt gtttattggt
    70261 tttattttat actataacac cataagtaaa attgttttat caattatcaa taaaataatt
    70321 cgttttgtga gaaattcttt taaaaaagtt acacattaca tagtcagttt tttaaataat
    70381 ttgtattacg ttataatcta ttcactacac ctactatttg atattatatt ttatatacca
    70441 aacatattta tagcaacaag aaaaagtata aaaagaaaat caaataaaaa attaaagaac
    70501 aagaaaaaat caaaacctaa gaagaaaaaa aataaaacta aaaaaagggt gtaggaaaaa
    70561 tgaacttaag aaaaaaattt tcaggacaga ttattgttat cagtttattt ttaggaatat
    70621 caatttttag tatgatgaca ggatttgtat ttgagtatac aaaagctaag gaatataaaa
    70681 aagaaatagc aagtctaaat aaacaattaa aaaagactga aatacaaata aacagcttaa
    70741 agaaagatga aaaatcatat gaaggagact tagaggatat agcaagaaaa agattgaata
    70801 tggtaaaacc aaatgaaaca gtttatgtag acataaatcg ttgattaaaa cttgctaata
    70861 agtttacaga tgtattgatt ttaaaattta agatttaata aaaaagtcat tcagttaagg
    70921 atggcttttt gtttttattg aggagggaat ttcataatga aagtaggagc tatagatatt
    70981 gggacaaact caatgagatt attgatagca gattatagag atgggaattt tataaacaga
    71041 aaaaaatttg ttaatacaac tagaattggt tatggtgtgg atagtaaagg atatataaaa
    71101 gaagatgcta tcaaaagaaa tataaaagca ttaaaagaat tttctgataa gtgtaatgat
    71161 gaaaagtgtg aaaaaattta ttgtatgggg acatctgctc ttagagacag taaaaatgga
    71221 gattactttg ttaaattagc taaagaagaa actggaatag atgttgatat agttacggga
    71281 atagaagaat caaatttggg ctttaagggt gttttagaag gaatacaagg tgatgatact
    71341 attattgtta tagatattgg aggaggttca acagaattta ttgtaggtga ttcagaagga
    71401 attatattta ataaaagtga gaatgtaggt gctcttagga tgacagagag gtttttgaag
    71461 cacgatatta ttgaagatga agagtttgaa gctatgagtt catttatata tggtgagatt
    71521 gataaaacgt taaatcatat aaaagacaaa ggattaaaaa ctcttatagg tataggaggt
    71581 acgattacat cattatcagc aatgaatcaa gaattagaga tttactctat ggaaaaaata
    71641 cataatagta aaatacacaa aaaagaaata gaagaaattc tacaaaaatt aataaagatg
    71701 acattaagtg ataaaaagaa cttaaaaggg ctacaagaaa aacgtgcgga tattataact
    71761 gctggtgtaa aaatattgaa tataataatg gaaaaattag aaatagaaga aataaccgta
    71821 agtgaatacg ataatttgga aggcttaata tgtcaaaagt caaaaaaaat gtattaatat
    71881 tttttgattt ttaaaaccga ttatgacaaa aaaaattact cctctttgtt acaattctta
    71941 atataaacaa aagaggaggt ttttttatgc aaagaagtgt agcagttgtg aagaataaga
    72001 ctgtaaaacc aaatgtcata aaattaataa gcggatatat tgattttact acggcggcat
    72061 tcgctgtgat gggattttta cttagtaggt ctattatagt agactctgta gctcctttag
    72121 gaattgcctt ttttatatgt gcatcaaaga ttgataagta caagatacct gtattcatat
    72181 caacattatt aggaatattg ttatcatcta atgattttgg aaatgtagca aaatatgctg
    72241 tgtgccttac aatatttatg gctatgaata aaaaattaaa attatcagat tcaattgcta
    72301 aggttgcatt tataggtgca ataatactac ttccaatctc catgggacaa gctttctttt
    72361 caaataggta tgtatatggt cttcttatag caggagtaga agcaataata atgtttatat
    72421 ctatatatgt gttttcttat gggataggtt taatggccaa tgtcaacaat aggatgtctg
    72481 tacggacaga agaagccata tcaataagtt tactgctaac ctttagcata atgggaatag
    72541 gagatatatc tctgtttgga atatcaataa ggaccatttt atcgaccgta ttgatattgc
    72601 tgacctcaat agtaggtgga gctactatgg gagcatctag tggtgtaatt attggtgtag
    72661 catccatttt aaataatatg acatcagctg tttatatggg gatatattct ttttcaggat
    72721 taataagtgg agcatttaat aaaataaata aatatttctg tatactagga tatattctaa
    72781 gttggacaat aatataccta tatacttctg gtattacttc taatatgatg caattaagag
    72841 atatactatt aggttgtttg atagtactag tattgccaga gcgattattt aataagattg
    72901 aaaaattaat aaaaagtaat gtggcttcaa atgaaatcgt atacgattat attatgagaa
    72961 gcaaaaacct aactaatagc agattgaaca gtatttataa aacttatgat gaccttgcag
    73021 atacatttga taagataaga gaaaaagaca aagtgctaga ccaaagagac atagctaatg
    73081 taatagatat gattcataat gatgaatgta aaagttgtag tatgagaaga atgtgctggg
    73141 agtcaagatt taatcataca tacactatga tatataacat tcttgaaaaa attgaggaga
    73201 aaggggagtt aagtctaaac gatataccta aaaattttag aaaggaatgt atgaaaccag
    73261 agtcaatagt gaaaatatca aatcactatt acaaaatgtt tgtattagat tatgattgga
    73321 gtgtgaagtt ttcagaaagt agaaagttaa tagcaaatca gataagaagt atttcaaaat
    73381 ccattaaatc cttatctcaa gatttagaag gcgacataat gctagatata gaaaaggaaa
    73441 aaaatatata tgaacagtta gaaagatatg atataacagt tgataaagta agttacttaa
    73501 caaaaagtaa cagtgagttt gaaatatcaa tagaaaagaa aacttgccat gatggatgta
    73561 tgtgtgaaga taaaattgta aatataattt cagacctagt aggggaaaat atgtctgtta
    73621 gaaaaatagg atgtcactgt ttaggaggta aatgcaaggc aacattcgtt aaatctcaaa
    73681 aatataaggc tgttacagaa gtttcagcaa tgtcaaggga tgggcatatc ctttgtggag
    73741 acaattacac atacatggag ataaatgatg gtaaatacat gatggctata agtgatggta
    73801 tgggaaaagg taaaaaagca tatgaagaat cttctgccac tattgatata ctggaaaaaa
    73861 tgatagatgc aaaaattaaa gatgagatag tcattgatac tataaataat atgttgttgt
    73921 taaagtcttc agaagagatg ttttcaactc tggatttggg aattttagat ttaaaacgag
    73981 gttgtttaga aactataaag atgggagcgt gttctactta tataaaaaga gaggatggag
    74041 aagttgactt aatatcgtca tcatcattac ctgtgggtat attatcagat gtaaaaattg
    74101 atagaaaaaa tgtaaaagtt aaggaaggag actatgttat aatggtttct gatggaattg
    74161 tagatgcagg aagaaataac aatttaggag acaattggtt aatatacttc ttaaagaata
    74221 tagagactac aaatccaaag gaaatttcaa atttaatatt ggatagagca ttagagttac
    74281 aagcgttaca aattgaagat gacatgactg ttttagttac gaaaatatgt acaaaataag
    74341 gtttacaaga ttatgtgtat aagatgtgga taacttgtgt ataatatgtt aatagacttt
    74401 tgaaaaaagt atagttatta acaaaaataa catataaatc aacaaaattt gttgataagt
    74461 atggcagaaa tgttaataaa atgtaaaaaa agaaaaaaca aaagctatta tcaaaagaga
    74521 ttcatgttga aataactaaa tttctaagta aagaaaacct gtgaatatgt tgattattat
    74581 gtggataact attaattcga tatttattta tatagtatga ataattgaat aatatatcta
    74641 aaaaaagcca tcctattatt aagtaaactt attgaaagga tggcttttta tgaatagaaa
    74701 attgtgcaaa gcaataatac ctttatttat ttctattttt tgcatgttaa taataagtat
    74761 aaaagctgac caaggatatc aaaagaataa tgatagagca attactgtca tgaataataa
    74821 tgatactgaa gatgatgctg aaaaaaaaca agaaatagac tatgaaaaaa catgttggaa
    74881 tttgcaatct ttgtttaaaa gtgatgacca atggaaaaaa gaacttaaga gttttgataa
    74941 agatactaaa gagttgaaaa attacatagg taaagtaaca aaatcgccaa cacatttgtc
    75001 ttttgcctta aacattaaag aaaaacttga tataagacta aataaacttt ctgcctatgt
    75061 aaaattaaaa caagatacta ataaaaattc gtataagtac ttagatatga atgatagtat
    75121 gagtaaatcc tatgggaatt atatggggat ttgttcagat ttagagttag aaatactaaa
    75181 attatcaaac aaagattaca agaaaattat ttcaaataaa aatataaata ggaaatatgg
    75241 tgcatattta agagatataa gaaggaataa agtacattat ttggatgata aatcagaaga
    75301 tattctaagc aaagtatctt caataagtag tcttccaagc caagtatatg aattatttag
    75361 aaatatggat agaaaaacta atttgacacc agctcaatat gcgagtgaat tagagtcatc
    75421 agatagagaa aatagaaaaa aagcttatca agatgaactt ataacttaca atgataatat
    75481 aaatacaatt gcaggtttaa ttactggtca agttaaaaag aatatttttt attctcagga
    75541 aagaggttat gagtcttctt tagaaatgta cctggaatct gataatgtag atgaaaaagt
    75601 atacaataat ttgataagga ctgtaaatag taatatggac agtctacaca aatatataga
    75661 tttaagaaaa aaagtattaa aattagataa ggttcattca tatgatatgt ttgtgcctat
    75721 ggttaaggct gttgataata atattaatta tgaaaaggca caaagtatag tatattcagc
    75781 gttgtcacct ttaggaaaag aatacaatga tgtagtatat aaagctttca atgaaaaatg
    75841 gatagatgtt tattcacatg aaaataaagt aagtggtgga tactgcttat ctgtttatga
    75901 aaatcatcca tatatacttt taaattataa taattcatta ggttcagttt cgactttatc
    75961 acatgagctt ggacatgctg tatatgaata tttaagttct aagaatcaga attattttaa
    76021 ttcaaatccg tctatattta ctcacgaagt tgcatctaca acgaatgaag cattacttta
    76081 cgagatgctt ataaaagaag ctaaaggcaa tgatgaaaaa gcttattata taacacagta
    76141 tttagacttg ataaaagata ctctttatac acaaactatg tatgctgaat ttgaaaaaac
    76201 tatacacgag ttagtagaaa aaggaaaaag tgtaaacgca ttagtattaa atgatgtttg
    76261 gggacaactt cttaaaaaat attatggaca aagctatgaa ttagaccaat tatctaaggt
    76321 cggatgggct agaatcccac atttttataa tagtttctat gtctataaat atgctacagg
    76381 ttgtagtgca ggagtaagtt ttgcccaaga catcctaaag aatggttcag ataactatat
    76441 gagctttctt aaaaagggaa gttcagatta tccaataaac ttgttaaaat caagtggcat
    76501 aaatttaact aatacaaaac ccatagaaaa tacaatcaaa aaatttgata gtttagtagc
    76561 agaacttgaa aagctattat aaacattatt gtaattcaca tggtaaatat atcgaattaa
    76621 tgataaaata tactaaaagt ttaaagtcct atcaagatag gactttttat ttattaatta
    76681 gtgggagatg attctatgca agttaaagtt aaaaaggctg taataccagc agcaggttta
    76741 ggaactagat ttttgccagc tacaaaggca caaccaaaag agatgttacc aatagttgat
    76801 aagccaactc tacaatacat aatagaagaa gctgtggcct caggaataga ggaaatacta
    76861 ataataacag gtagaaataa aaaatctatt gaagaccact ttgataaatc tgtagaattg
    76921 gaacttgatt tagagaaaaa aggtaagaaa gaattgttgg aggtagtaca aaacatatct
    76981 aacatgatta acatacatta tataagacaa aaagagccaa aagggttggg agatgcaatt
    77041 tattgtgcga ggcattttat aggtgatgag ccgtttgcag taatgttagg ggatgatatt
    77101 gtagataatg atgtaccttg tctaaaacaa ctaacagatg catatgagga atatagaact
    77161 acaatattgg gtgttcaaaa ggtaaatcaa gaagatacta ataaatatgg gataatagaa
    77221 gcaaaaaata tagaaggtag agtttacaag gtaaaagaca tggtagaaaa gccagagtca
    77281 ggaaaagctc cttcaaatat tgctatttta ggtagatata taataactcc tgaaatcttt
    77341 gatattctta aggatttacc accaggtaaa ggtggagagg tacaacttac agatgcttta
    77401 aaaatattat ctaagaaaga agctatgtat gcatacaatt ttgaaggcaa gagatatgat
    77461 gttggggaca agctaggatt tttagaagct actgttgact ttgctctaaa gaaagaagac
    77521 cttaaggaag attttataaa atatttgaaa catgtatgta gtgaatttga taaaaataac
    77581 aatgtgttat acaataatac agatgaaaaa atagatttaa ttgaagtcaa tgaagctaga
    77641 gaacttgaaa ttcaaaaata attaatgaaa ggtgatgtat ggtggcaaaa tcaagtcaga
    77701 aaagaattaa tagaataata gctgttggga ttgtgggaat cctcgtaata acgagtataa
    77761 cagctgtttt gagtatgatt gcaactatgt aataagataa atgacagcag ttgatataca
    77821 taaatataaa aaccatatat aacttgatgt agtcaaaaac ttacaatatt ttagttatat
    77881 atggttttta gaatttataa atgtaaaaaa aaatttttat aatagttgca tattttaaag
    77941 gaaaatatta ttataagata taaatatagt gataaattta taaaaacgtg ctaagattgg
    78001 acttgaaata cagtaatata gtaggtaata atgttttaaa ttttatttat tgaccataat
    78061 atataaataa tgatattatt agacttaact gtttaaataa aacttttctt tttcatgcct
    78121 tcaatttcca aaataagtat gtatataaat gaatatatag atgaggagga tttttttgat
    78181 tttagatgat aaagtattag aaggattagg tagtaagacc ttagttgagc tacgagagat
    78241 agctaaagaa ttaaaaataa aatcaattac tacatataag aaaaatgagt taattgagat
    78301 tataaattcc aaaagtaaaa atgaggaaaa agtaaacgaa gagactaaag aaaaaaatga
    78361 agatattaaa gaagacataa agaatagaaa agaaaatata gagcgtgaaa gtatagaaaa
    78421 agaagttgaa tataagagcc ctaccaaatc atacaacaag aaagaaatag atacccaaaa
    78481 tatttcccaa aaccaagaac atagaaatca aagaaatgac tataataaga caacgagtgt
    78541 aaatgatagt aataagtcat caaatatatc taatagaatg gtcagaaata ataataaaaa
    78601 ctattatatg cctaaacaag ttgatgaatc taagatagta gatgaattta acacatcaaa
    78661 agaggatgaa gtagtaggtg tacttgaaat tctgccagat ggatttggtt ttttaagagg
    78721 ttcaaattat ttgtctactg aaggagatgt ttacgtttca ccatctcaaa taagaagatt
    78781 taatatgaaa acaggagaca agattaaggg aataactaga catccaaaaa gtggagagaa
    78841 atttagagca cttttatatg ttcaaaaaat aaatgatgaa aaccctgaca cagctataca
    78901 aagaaatgcg tttgagacat taacaccaat atttccagaa gaacgactta cactggaaac
    78961 taatagaaat gaaatagcta caagaattat agatttaatt tcacctatag gaaaaggaca
    79021 aagaggattg atagtagcac ctccaaaagc tgggaaaaca gttcttttaa aaagcgttgc
    79081 aaatagcata gctaaaaatc atccaaatgt tgaacttata gtactcctta tagatgaaag
    79141 accagaggaa gttactgata tgaaagaatc tattgaagga gacgttatat attccacttt
    79201 tgaccaagta tcaagtcatc atgtcaaggt tgcagagatg gtgttaaata gagctcaaag
    79261 attagttgaa catggtaaag atgtagtaat tttactagat agtataacca gattggcaag
    79321 ggcatataac cttacaatat ctcctacagg tagaacttta tctggaggta ttgaccctgg
    79381 tgcacttcat ggacctaaaa agttctttgg tgcagcaagg aatattagac agggtggttc
    79441 tttgacaata ttaggaacag cattggttga aactggttct aggatggatg atgtaatatt
    79501 tgaggaattt aaaggtacag gaaatatgga gctacattta gatagaaaat tagcagaaaa
    79561 aagaatattc cctgcaatag atatttacaa gtctggtaca agaagagatg atttattgct
    79621 tgatgatgaa gaaaagactg ctctttggag attaagaaga gaaatgagta ataattcagt
    79681 aatggaaatt acagataaag tcattgaact tataaagaga actaaggaca ataaagagtt
    79741 tgtaaaatca ataaagaatt tgtaaaatca ataatacaaa tgcaaatatg gattatataa
    79801 actaatagaa aaatcacttg aatggcataa taagttgtgc tataataatg tagttgataa
    79861 tgtaaaaaga aagttaatat aattaatttt tttaaataaa gagaagaggt gactataatg
    79921 caaaaggaaa tacaaccaaa atacaatcca gttgaagtgc gttgtgcttg tgggaacaca
    79981 tttgttgctg gttcaactaa ggacgaaata aaagttgaaa tatgttcaga gtgccatcca
    80041 ttctatacag gaaaacaaaa gaacatagaa aaaggtggaa gaatcgacaa attcaagaaa
    80101 agattcaaaa tggactaatt tttataaaag tggagttgga ggaagccaac tcctatttta
    80161 ttacaaaaaa acattcatat tctactttaa attgtctttt tgtattataa taataaatat
    80221 gtaaaattga gtattctaaa tacaataaaa tgaggtgagt ggatggcaaa acaagctgta
    80281 ggtgggcaag ctgttattga aggtgtaatg atgcagtcaa aagacaaaag agcggtagct
    80341 gttagaaaaa gtgacggaga aatagcacta aaagaagata gaataaaaag ttgggtaaga
    80401 gataagaata tagataagat accttttgtt agaggttctt ttgttatgat agatacaatg
    80461 attcaaggca taaaaagttt aaacttttct tcagagtttt ttatggaaga agctgaagag
    80521 gataaatttg atttatttat aaagaaaatt tttaaagata aggcaaatga tataattata
    80581 atattttcat tggtcatagc aatgttactt tctgctggat tattcatttt tatacctaca
    80641 ttggtaggag gagctttttc taaagtaatg cctaatgatt ttatgcttaa tttaatagaa
    80701 ggaatcataa ggatagctat attatttgca tatatagtat tgatttcacg aagtaaggat
    80761 atagaaagag tctttcaata tcatggagca gaacataaat ctatatattg ctatgaaaat
    80821 gatttagaac ttacagtaga gaatgctaga aaatttaaaa gattacatcc tagatgtggt
    80881 acaaatttcc tatttatagt tatggctgta tcaataatat tgtttgcatt ttttggttgg
    80941 ccaaatccaa ttcttagaat atttatgaga attatatgtg tgcctatagt agcaggttta
    81001 tcttatgagg taattagagt tcttgggaaa tatgataatg gatttactaa aattattgca
    81061 tatccaggaa tgatgttgca atattttaca acaaaagagc ctgatgatga gcaattagag
    81121 gttgctttgg aagcattgaa agcagtagta gattagagaa aaggatattt gttatgacga
    81181 taaaagatat aattattaaa tattcagata aactaaaaga tataagtgat actccaagat
    81241 tagatacaga gttattgtta caaaaaacat tgggtgttga tagattatat attcacttaa
    81301 atctgaataa agagctaact gaagaacaaa aaacaaaatt tatgggtttt gcagaagaaa
    81361 gattaaatgg aagaccaata gcatatatag ttgaaaatag ggagtttatg ggattagatt
    81421 tttttgttaa ggaaggcgta ttgattccaa gaccagatac agaaacttta gtagaagaaa
    81481 taattgaaat atgtagagaa aaaaaagatg taagtatatt agatatagga actggttctg
    81541 gagctattac aataagttta gcaaagtaca ttgaaaattc taaaatcatg tcttttgata
    81601 tatcagagac agcattagaa atagctaaaa aaaatgctat tataaatgaa gttggtgaaa
    81661 aaataaagta tattaattct gatttattta cagcaataag tgatagtaac ataaaattcg
    81721 atatcatagt ttcaaatcca ccatatatta aaaaacaaga tatagaaact ctgcacaaac
    81781 aagttaaaga ttatgaacca tataatgctc ttgaaggtgg agaagatgga ttagactttt
    81841 atagaagaat aacagaacaa ggtaagaaat atttaaataa gtgtggaata ttagcatatg
    81901 aagttggtca taatcaagct gaagatgtaa taaatattat gaaaagtaat ggatataaaa
    81961 aaatatacac aaagaaggat attcaaggca ttgatagagt tgttataggt tacaatatat
    82021 gatataatca acaattgata tgttacattt aatcgaggtg aaagtatgtt aaaaaaatta
    82081 gaggtattgg aagatacata taaagactta agtgaaaaaa taggtgatcc ggatgtaata
    82141 aatgatcaaa aagtttggca gaaatatata aaagaacatg ctgacttgga acctattgtt
    82201 atgaaataca gagagtataa aagcgtttta gatagtataa aagaatcaaa agaaatttta
    82261 caagaagagt cagatgaaga attaagagaa ttagctaaaa tggagttagc tgagatggaa
    82321 gaaaaagtag cacctctgga ggaagaaata aaaatactat tattgcctaa agaccctaat
    82381 gatgataaga acgttatagt tgaaattaga ggtggagctg gaggagatga agcagctcta
    82441 tttgctggtg atttatttag aatgtactca aggtatgctg aaagaagaag atggaaaata
    82501 gaattattga gtgcaagtga tactggagtt ggtggatata aagaagtatc ttttatgata
    82561 aaaggtaaag gtgcttattc aagattaaag tatgaatctg gagttcatag agttcaaaga
    82621 ataccatcaa ctgaatctgg tggaagaata cacacatcaa cttctactgt tgcagtatta
    82681 ccagaagttg aagatgtaga ggttgaaata aatccaaatg atttaagaat agatgttttc
    82741 cgttcttcag gtaatggagg acaaagtgtc aatactactg actctgctgt tagggtaaca
    82801 catataccta caggtgaagt agtatcttgt caagatggaa aatcacaatt aaaaaataaa
    82861 gagcaagctt taaaaatatt aaaagctaga ctttacgata aagcattggc agaacaacac
    82921 aaagatatag cagcagaaag aaaaagccaa gtcggaacag gagacaggtc agaaagaata
    82981 agaacatata atttccctca aggtagaata agtgaccata gaataaattt aactttatat
    83041 aagttagatg cattcttaga tggagatata gatgaaatga tagatgcttt aattactgtt
    83101 gaccaaacag aaaaaatgac tgcaatataa gtaatgtttt aaagaagctg tttcttccta
    83161 gaaattattt tctattttga aacagctatt ttgcatttta ggtcatgtta tcatattcta
    83221 ttgtatataa ttgttatata caagtatagg agggttatat gatactaaaa gtaacaataa
    83281 ttgggctttt ggcaggtgtt atagggacag gattaggagg agtaatatca gccattttta
    83341 aaagagaggt cgataaatat ctaagttttt ttatgggatt atctggtgga ataatgttgg
    83401 ctgtagtggt gtttgattta atgaaagaat ccatggacaa aatggggata atcaatacag
    83461 ttatatttac gtttgttgga gctctcataa ctatgtacat aaaaacaaaa ttagatgtgt
    83521 ctggaaatat ggcatctgga tatcttatat tcataagtat attactacat aatttaccag
    83581 aaggactagc cattggttct tcttttatgt caactgaaag tttaggtatt acacttgcta
    83641 tagttatagg tctacataat ataccagaag ggttagctat ggcattaggc ttagtttgca
    83701 ataaaatgaa actaagtaaa gttattttgt ttactgtaat agctggatta cctatgggtc
    83761 taggaagttt tttaggtgtt tattttggag gagtatttac ttctcttata ggagtatttc
    83821 ttgctacagc aggaggtact atgatgtatg ttgtattgga agaaattttt ccacattcaa
    83881 aaagtgtgta ttgtataatt ggtttcttgt taggtacaat gattgtaaat tatatataaa
    83941 attaaaatga aagcaggcat acaaaagatg aaaactatta taagtaatat tgatataaat
    84001 aatattgatt atgaggaaat aaaaatacaa gcaaaacttc ttagagaagg taaaacggtt
    84061 atttttccaa ctgagacagt atatgggttg ggtgcaaatg cattagatga aaatgcagta
    84121 aagaagattt atgaagctaa aggaagacct agtgataatc cattgatagt ccatatatat
    84181 gaaaaagaag aagtatatga cttagccaaa gatataagtg ataaagctaa acttgttata
    84241 gaaaagcttt ggccaggacc tataacaatt atattaaata aaaaagatat aattccatac
    84301 aaaactagtg gagggcttga tacagttgca ataaggatgc cttctaatgt tattgccagg
    84361 gcaataataa aagaagctgg tatacctatt gcagctcctt ctgcaaatat ctcaggtcgc
    84421 ccatctccaa caaaagcaaa acatgtatat gaagagatga atggaagagt ggatggaata
    84481 gttttaggag gagacagtaa ttttggattg gagtcaactg tattggattt aacagaagag
    84541 actcctatga tactgagacc aggaagtata actaaagaag ttttagagga acttcttgga
    84601 gaagtaaagc ttgacccatc attaagtaaa aaagaagata atcaaaaagc taaagctcct
    84661 ggaatgaaat ataaacatta ttctccaaat gcagatgtat atataatatc tggaaaaaga
    84721 gaaaatgtag caacaaagat taatgatatg ataaaatcta atagagacaa aggtctaaag
    84781 acaggtgtaa tgtgtattag tagaaaccga gagttttatg atggagaagt aatcgattta
    84841 ggaaactctc ttgaagaagt tgcaagtaat ctgtttgatg ctcttataga aatggacaaa
    84901 aagggtgttg atgtcatata ttcagaagag ttccccaaga ctggagttgg acaagcaatt
    84961 atgaatagac tactgaagtc agcaggatac aaagtgataa aggcttaaga gggagttgta
    85021 aaatatgaat atacttattg tgtgtacagg taatacttgt agaagcccta tggctgaggc
    85081 tatactaagg aaagcaatta aagaatctgg aagaagtatt gaagaatatt ctatatcatc
    85141 agcaggtata tctacagcaa atggaatggg tgcttctgaa aattctatag aagtactaaa
    85201 agaaatcggt atagacttat caaatcatag aagtaaagta attactaaaa aattaattga
    85261 tgaatcagat ataatactaa caatgactaa atctcataaa gaaattttag tacaagcagt
    85321 tccaaaatgc aaagaaaaag tgtatacttt taaagggttt gcaaataaaa atgaggaaga
    85381 tatatctgac ccatttggtg gaaatttgga tatttataga agcactatga gagaaataat
    85441 gtattctgtc aacgaaatag taaaaaaaat atgaaacgga ggataaacaa atgaagatag
    85501 gattaggctg tgaccatgga ggatataatt taaaaaaaga aataataagc tatttagaaa
    85561 gtaaaggtat agagtgtgta gattatggaa ctaataatgc tacagattct gttgattatc
    85621 ctgtttatgg agaaatagtt gcaaattcag ttataaataa agaagtagat tatggaatat
    85681 tatgttgtgg tacagggata ggaatatctt tagctgctaa taaggttcct gggataagat
    85741 gtgcagttgt atcagatgta ttttctgcaa aaatgtcaaa agcacataat gatgcaaata
    85801 tgttatcatt aggcgaaaga gttttaggaa aaggtctagc acttgagata gttgaagcat
    85861 ggattaatac ggattttgaa ggtgatagac atgctagaag agtaaacatg attaaatcaa
    85921 tagaagaaaa acataataaa taataaaaat tacagtttta tcaggaggaa ttatcaaaat
    85981 gagcaaagtg gtagagacaa accatccatt aatacaacat aaattaactt taatgagaga
    86041 taaaaatact ggttctaaag actttagaga gcttttaact gaaattgcaa tgttaatggg
    86101 gtatgaaata acaaaagata taccattaaa agatgtagaa atagaaactc ctattcaaaa
    86161 aacatcatct aaagtagttg caggtaaaaa attagcaata attccaattt taagagcagg
    86221 tcttggaatg gtagatggat tagtgagctt aatgccagca gcaaaagttg gacatgtagg
    86281 actatataga gacccagaaa cattaaaacc agttgaatat tattgtaagc ttcctcaaga
    86341 cataggagaa agagatataa tagtagttga ccctatgctt gcaacagggg gttctgctgt
    86401 agcagctata gatttactta agtctaaagg agctaaaagt ataaaattag ctaatttagt
    86461 agctgcacca gaaggtatag cagaagtgca aaaatatcat gatgatgttg atatatatgt
    86521 tgcatcagtt gacgaaagat taaatgaaca tggatatata attcctggtc ttggtgatgc
    86581 tggagataga ttgtttggaa ctaaataaaa ataaataact ataaatattt attagggact
    86641 ttcttatata gtgtatataa ttttatgtaa gaaggttctt ttttatatat tttttctcaa
    86701 aataggaatt attgaattga taaatttctc gaattgagaa taaaaagttt ttaccaatta
    86761 aaaaagattg cttattttac aaggttttat agaatagtag tctattttaa tgtggcatgt
    86821 tagttgctta cgattatagg tattaagtgt attagttaaa ttgagaattg aatattaata
    86881 atattattgg gagtggtaat acatgaagaa ttgtatagta gtaagagggg ctggagattt
    86941 agcaacagca gttattcata aattacacaa cagtggtttt aaagtagttg cgttagaaat
    87001 agaagagcca ttagctataa gaaggcaaat ttctttttgt gaggctgttt atgaaaaaaa
    87061 agtaactgtt gaaggtgtag aatgtatatt ttgcaatact gaaaaagaaa tagaggaagt
    87121 tttatctcaa cataaagtag ccttgattat agacccaaaa ggagaaaaat tatctaaatt
    87181 aaatccaatc gttttggttg atggaatact cgctaagaaa aacttaggta caactaaaga
    87241 tatggcacca cttacaatag ctttaggtcc tggattttgt gcaggagaag atgtagatgt
    87301 tgttatagag acaatgagag gtcataatct aggaagaata ataactaatg gtagagcaga
    87361 aaaaaataca ggagtaccag gagcaataaa aggtttttct aaagagagag ttatgcattc
    87421 acagtatgat ggcataatgg aaaatgtatg taagataggt gatatagttg aaaagggaga
    87481 cctactttgc tatattaata attatgaaaa aaaacatgaa gttagagcaa caatatctgg
    87541 agtccttaga ggtttattaa aggatggagc aaaggtaaac aaaaatttaa aaatactaga
    87601 catagaccct agaaaagaag aagttaagaa tgcttttaca atatcagata aagctagatg
    87661 tatagctgga ggggttttag aagccatact aaacaatggg atttatcccc aaaattaatt
    87721 tatattagat aaagctatta atattttatt aagatgatat aataaattta atagattaaa
    87781 gagagcatat gacgggtatt taaaatttaa atggtaaaaa tgctcttttt ttattggaca
    87841 ttcaattaac atgtgtatat aatataaaaa taagtattta tttaggttga aatctaataa
    87901 atatataata ccagtacata agcaaagagg agaaaagtaa attatgagac catcatggga
    87961 tgaatacttc atggaaattg cagaagtagt gaaaaagcgt tcaacttgta ttagaagaca
    88021 agtaggagct gtaattgtaa gagacaaaca aatattaaca actggatata atggttctcc
    88081 gagaaatctt gaacactgtg aaaatattgg atgtaagagg caggaattaa atattccctc
    88141 aggagaaagg catgaattat gtagagcatt acatgctgaa caaaatgcga taatacaagc
    88201 tgctcataat ggtattagtg tagatggggc aactttgtat gttactacaa gaccttgtgt
    88261 tttgtgtgca aaaatgtgca taaatgcagg tatattgaaa attgtttatg aaggtgatta
    88321 tccagatgat atgtctacag aattattaaa agaagcagga atagaactca taaaatttta
    88381 gtggataaaa tttatatgac aataaatgtc aaattatgac actgaaatac aatggtatca
    88441 aatgattaaa agaaagtatt tgaaaaatca tcagattagt agtaagatat attttataat
    88501 taaataaatt tatgagatag attaattaca tgttatttat tttataataa tgagggatac
    88561 tatttatgag taaaagaaat acacatacag aaattgcaaa gttgtttagt ttaataagtc
    88621 aaataggatt gatgattgta atatcaatat taggatgtac tttcttagga aaatttttag
    88681 atagtaaatt gaatactact ccagttctga caataatatt tttattgttg ggtgttggag
    88741 gtgcttttag tggtgtttat aaaactctaa tagtatatac acgaaggaag tgatatattg
    88801 gatataaaat tacttaacca ggtaaggtca gtaacaaaag gtatagtaat atttgatgta
    88861 gttttaattg tgctaatgtt gataacatca acattaagta aaccagtatt attaggactt
    88921 atatttggct ctataatagc tatgttaaat tttagattat tggcgatatc actggaaaaa
    88981 tcagtgacat ttcctgctgg gaaggcacaa gcttatgcat cagcacaata tgctgttaga
    89041 ttatttataa tggcagttgt tctaattgca tcagctacag taccacattt aaatataatc
    89101 ggaacagcat tgggattatt gagcacaaag tttgtcatat tatcaaaaaa ctttataaat
    89161 aaattaaaga ggaaggaggc ataagtatga atcaagcgca ttattatctc ataggaaact
    89221 ttaagattag tgaaacaata ctagtaagtt ggggaataat ggccttttta gcgatagcat
    89281 cttatttttt gactagaaac ttaaaaaaag ttccaactag taaagttcaa atattcttag
    89341 aatttgcagt aggtggtctt gctaaaatgg ttacagatgt tatgggtaaa aatacagtaa
    89401 aaagaatgcc atatatgata ccatacatag gaagcttgtt tttatttttc gcatgttcaa
    89461 atttaagccc attacttgga ttaaggtcac caacaaccga cttagacaca actgctgcat
    89521 gggcaatgat tacatttttt atgatttatt ttgcaggagt taaatttaag gggttatcat
    89581 actttaaaga attggctcaa ccacttgcca taatgttacc aatcaatatt ataggtgagt
    89641 tagctagacc aatatcatta agtttccgtc catttgggaa tattttaggt ggaacaataa
    89701 taatgggtct gttttatcaa cttttaggtt ttatatctag tttaatacca ggattatcaa
    89761 taccaattgg agaaatatta ataccagtcc cattacactt gtactttgac ttatttgcag
    89821 gattgttaca agcatatata tttataatgt taacaatggt atttatatca agtgcaggag
    89881 agttagatta agaaatcaac ttatattaag ataaaaataa aataatttaa aaaattaaag
    89941 ttttaaggag gaaataatta tggaaacagc aatagtagcg gcagcatcag caataggagc
    90001 agggatagca gttgcaacag gtataggtgc aggtataggt caaggtatag cagcagctaa
    90061 agctgcagaa gcagtaggaa accaaccaga agctaaaggt gatataacat caactttatt
    90121 actaggagtt gctatagcag agtcttcagc aatatatggt ttggttatat caataatact
    90181 tctattcgta aatccattct ttaaatactt aggaatgtag atttagtcct taaatatttt
    90241 gagataggtt tataggtaaa tcatctcaaa cttataatca tgagatgaac tttatcatct
    90301 cgtgattata agtagttatg atttatggaa aggaggataa ttatggaaaa agcactagta
    90361 ggtataacgt gggaatttgt gttccaaatt gttaatactt ttataatatt tttacttctg
    90421 agaaagcttt tattcaagcc agtattaaat ataattgaat caagagaaaa tgatattaaa
    90481 agtgatttgg cagaaggcga aaaagcaaaa aatgaaggtt tagctctgaa aaaagaatat
    90541 gagtcaaaaa tcaattttgc caaggatgaa ggtcaagaaa tcataaaaca agcaactata
    90601 agagcagagc agaaatcaga tgatatagta aatactgcaa agaaagatgc tcttgatata
    90661 aaagaaaaag caaacaaaga tatagaacaa gaaagacaaa aggttataaa tgaaatcaaa
    90721 aatgatatat ctaacatagc actacttgca gcatctaaag tcattgaaaa agatttagat
    90781 aaatctaaac atgaagaatt gatagaaaac tttataaaag aggtagggga agctaaatga
    90841 taaatgtaat agcaaataga tatgcagaag ccctatttca attaggagaa gaagaaaatt
    90901 caactgatgt cttattcaaa gaactagaaa aagtagtaga tatgatgact aaagttagta
    90961 aagatttcta caaagtttta aaatcaccat tagtttcaaa atcagaaaag aaaaacttgg
    91021 tagaaattat ttttagtaaa gaagtaagtt ctaacataaa aaacttttta aaagttttag
    91081 tagataaaga tagaatatca tatttagaag atatcgaatt agcttataaa gaattattaa
    91141 ataagaaaaa caatgtaatt gatggagtag caataagtgc tattccaatg agtgaaacag
    91201 atattaaaga acttgaagtc aaactttcaa ataaatacaa caaaaatgtt actatagaaa
    91261 atgttgttga caagactata ctagggggag ttctagttag aattggaaat gaacaaatag
    91321 atggcactgt gaaaactcgt cttgataaga tgaaagaaaa gctatctgaa gtaatatctt
    91381 aagaatggcg gtgaacccat gaacttaaaa cctgaagaaa taagttctat aattaaacag
    91441 caaataaaaa attatgagaa taaagttgag ttgacagata caggtagtgt tttaacagtt
    91501 ggggatggta tagcgagtgt atatggatta gaaaaagcta tgtctggtga gttgctagag
    91561 ttcccaggtg aaatatatgg tatggcactt aacttggaag aagaagtagt tggagctgtt
    91621 atccttggag atgacagtga aataaaagaa ggcgatatag ttaagagaac tggaagaata
    91681 gttgaagttc cagttggaga agctttaata ggtagagttg taaactcact aggtcagcca
    91741 atagatggaa aaggacctat agcgtacaca aaaactagac cagttgaatc tgaggcacct
    91801 ggtataatag atagaaggtc tgtttatgaa ccattacaaa caggaatcaa atcaatagat
    91861 tcaatgatac caattggtag aggtcaaaga gagttaataa taggtgacag acaaactggt
    91921 aaaacatcta tagttattga cactatacta aatcaaaaag gaaaagatgt tatctgtata
    91981 tatgtagcaa ttggacaaaa acgttctact atagctcaat tagttagctc tttagaaaaa
    92041 ggtggagctt tggattatac aatagtagtt tcagcaacag catctgaatc agcaccactt
    92101 caatatatag caccatatgc tggagcagct atgggtgaag aatttatgta caatgggaaa
    92161 catgtactta tagtgtatga tgatttaagt aaacaagctg ttgcatatag agaaatgtca
    92221 ttgttactta gaagaccacc aggacgtgag gcatatcctg gagatgtatt ctatttacat
    92281 tcaagattac ttgaaagagc agctaagtta tctgatgaat tgggtggagg ttcaatgact
    92341 gccttgccta taatagaaac tcaagctggt gacgtttctg catatatacc aacaaatgtt
    92401 atatctataa cagatggtca aatatactta caaccagagt tattctattc aggtgtaaga
    92461 ccagcagttg accctggtat atcagtatca agggttggtg gttctgcgca aattaaagca
    92521 atgaaaaaag ttgcaggaac attaaaactt gcatattcac aatatagaga acttgcagca
    92581 ttctcacagt ttggttctga cttagatgaa gatactaaaa agagacttgc tcaaggtgaa
    92641 agaatcgttg agatattaaa acaaggtgag catcaaccaa taaaagttga aaatcaagtt
    92701 atgataatat atgctgttat aaataatcat ttagaggata ttccgataga taatatagct
    92761 agatttgaat cagaattgta tgcatttgta gataataatt atccggaaat atcaagaaaa
    92821 atattaggtg gagaagactt cactcatgat ttaacagatg caataaatga atttaaagaa
    92881 aagtttgttg ttgaagtata atccttttta aaaaaggagg taaattaatt ggcaggagct
    92941 ggaatcaaag caatcaaaac acgtatggga actgttgaaa gtacaaagca aataactaaa
    93001 gcaatggaat tagttgcatc ttctaagctt agaaaagcaa aagaaaaggc tgaagattca
    93061 agagaatatt ttaatacttt atacaataca gtaaaagata ttgcccaaac aacacgtgga
    93121 attagaaatg aatttttaaa agaaagagaa gtaaaaaata aatgctatgt agtagtagct
    93181 ggagacagag gacttgcagg tggatacaat tctaatgtat taaaggaatc tgtctctcat
    93241 atgaaaggta aaaaggaaac agtgattact gttggaaaga aagcacatga atttttttct
    93301 aaaagaaact acaatatagc aaaagatata aatagtgttg aagcttgtgg atatgaagat
    93361 gcgacagaaa tttcacaaac tattattgac ctgtataaaa aaggtgaagt agatgaagtt
    93421 tatattgctt atacaaaatt taaatctgct ttatcacaag aagttgaaat tttgaaattg
    93481 cttccattag tctttgaaaa agatacagac gaacaaggaa tggcagtaaa agaagaaaaa
    93541 caaaatagat caaaagtaca atatatacca tcagcagaag cagttttaag ttatattgta
    93601 cctcagttta tatcaggtac agtatatggt ggaattttgg aatcttttgc atcagagcaa
    93661 ggtgctagaa gaactgcaat ggaatcagcc acagacaatg cgaatgaaat gctatctaat
    93721 ttagagttaa gttataacag agcaagacag tcagctgtaa ctcaagaaat aacagagata
    93781 gttggtggag ttgaagctct aaaataggga ggttaggaaa tggcaaatgt aggtaaagta
    93841 gtacagattg taggagctgt actagatgtt aagtttgata gtgaacaaag cctacctaac
    93901 ttattaaatg cgttagtaat aaagttagga gataaagaaa tagttgcaga agttgctcaa
    93961 catataggtg atgatactgt aagatgtata gctatgagtg caacagacgg acttgtaaga
    94021 ggtatggaag ttgtagatac aggagggcca ataagtgttc ctgttggaga tgaaacttta
    94081 ggtagaatat tcaatgttct tggaaaacca gttgatggga aaccagctcc aaaatctgca
    94141 cctaaattac ctatacatag accagcacca gcatatgatg aactagaaac tacagcagag
    94201 atactagaaa ctggtattaa ggtagttgac ttactagctc catatctaaa aggtggaaaa
    94261 ataggtctat ttggaggagc aggagtagga aagacagttc taatacaaga gcttataaac
    94321 aatattgcta agcaacatgg tggtatttct gtgttttcag gagtaggaga aagaacaaga
    94381 gaaggtaacg acctttatgg cgaaatgagt gagtctggag ttataaataa aacagctcta
    94441 gtatttggtc aaatgaatga accacctgga gcgagaatga gagttgcttt aactggactt
    94501 acaatggcag aacattttag agatgagcaa ggacaagacg ttttactttt cgttgataat
    94561 atattccgtt tcacacaagc tggttcagaa gtttcagcac ttctaggacg tatgccatca
    94621 gctgttggtt atcagccaac attagctact gaaatgggtg cacttcaaga gagaataaca
    94681 tcaactaaga aaggttcaat aacatctgtt caagcagtat atgtaccagc agatgactta
    94741 actgacccag caccagctac aacattctct cacttagatg caaaaacagt tttatcaaga
    94801 caaatatcat cactgggtat atatccagca gttgaccctc ttgaatctac atcaaggatt
    94861 cttgacccta gtatagtagg aaaagaacat tatgaagtag ctagaggtgt acaatcaata
    94921 cttcaaagat ataaagaact tcaagatata attgctatac ttggtatgga tgaattatct
    94981 gatgaagata agttaatagt tgcacgtgct agaaagatac aaagattctt atctcaatca
    95041 ttcacagttg ctgagcaatt tacaggaaat ccaggtcaat atgttcctgt taaagagact
    95101 gtaagaggat ttaaagaaat tcttgaaggg aaacatgatg acttaccaga gtcagcattc
    95161 ttatttgtag gaacaataga agacgctgtt agaaaagcga agggaagtat gtagtcatgg
    95221 ccagtgaatt ttcattgaaa gttgtaactc caagtaatac tttttatgat ggagatgttg
    95281 aaatgatagt agttagaact acaaaaggag acaaaggggt gttgaaaggt catataccat
    95341 ttgtttcagg tatacctgta ggaactttaa agataaaaaa agagggaagt tttaaagagg
    95401 cgaaaatagc agaaggattc attaatgtaa ctcaagataa aactgtcata ttgacagaat
    95461 ctgctgagtg gatttaataa attaatttag agtataaaaa gtcattttga ccaaaaaaac
    95521 ttttgggtaa aatggctttt ttgcgttttg gtgttaataa aataacgata aaattgtaag
    95581 tttttagtga taataaattc acaaaatgtt taaatttact gccaaattat gttgtaatta
    95641 ataagataaa gaagatttag atagctttta tgtaagtgaa aaagtcttca tataagaaat
    95701 acatataaaa tttttataaa a
//
LOCUS       DAEHWO010000006        89167 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEHWO010000006 DAEHWO010000000
VERSION     DAEHWO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 89167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89167
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.006"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(402..1493)
                     /locus_tag="KNP54_000596"
     CDS             complement(402..1493)
                     /locus_tag="KNP54_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBF0891525.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            complement(2261..4180)
                     /gene="thrS"
                     /locus_tag="KNP54_000597"
     CDS             complement(2261..4180)
                     /gene="thrS"
                     /locus_tag="KNP54_000597"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBF0891526.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     misc_binding    complement(4244..4482)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5094..5696)
                     /locus_tag="KNP54_000598"
     CDS             complement(5094..5696)
                     /locus_tag="KNP54_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBF0891527.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     gene            complement(5876..6694)
                     /locus_tag="KNP54_000599"
     CDS             complement(5876..6694)
                     /locus_tag="KNP54_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBF0891528.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            complement(6697..7458)
                     /locus_tag="KNP54_000600"
     CDS             complement(6697..7458)
                     /locus_tag="KNP54_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891529.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            complement(7948..9060)
                     /locus_tag="KNP54_000601"
     CDS             complement(7948..9060)
                     /locus_tag="KNP54_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0891530.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLLTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDFIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            complement(9186..10190)
                     /locus_tag="KNP54_000602"
     CDS             complement(9186..10190)
                     /locus_tag="KNP54_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0891531.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            complement(10478..11326)
                     /locus_tag="KNP54_000603"
     CDS             complement(10478..11326)
                     /locus_tag="KNP54_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBF0891532.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(11362..11832)
                     /gene="trmL"
                     /locus_tag="KNP54_000604"
     CDS             complement(11362..11832)
                     /gene="trmL"
                     /locus_tag="KNP54_000604"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBF0891533.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(12026..13195)
                     /gene="nth"
                     /locus_tag="KNP54_000605"
     CDS             complement(12026..13195)
                     /gene="nth"
                     /locus_tag="KNP54_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBF0891534.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKEEINKKGMNKKDIIEKEEINKKGMNKKDIIEKEEINE
                     KGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKGETEKKTKKSSSNKATQ
                     KTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNYGTAFELLIATILSAQC
                     TDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKSQKIKDTSEQLCELY
                     DGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSNRIGIVDEPNPQK
                     TEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCNYYKELNETK"
     gene            complement(13393..15630)
                     /locus_tag="KNP54_000606"
     CDS             complement(13393..15630)
                     /locus_tag="KNP54_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0891535.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(15736..16650)
                     /gene="queG"
                     /locus_tag="KNP54_000607"
     CDS             complement(15736..16650)
                     /gene="queG"
                     /locus_tag="KNP54_000607"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBF0891536.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLNYDEIQNISNKEFKR
                     KYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            17672..18076
                     /locus_tag="KNP54_000608"
     CDS             17672..18076
                     /locus_tag="KNP54_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBF0891537.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(18333..19328)
                     /locus_tag="KNP54_000609"
     CDS             complement(18333..19328)
                     /locus_tag="KNP54_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBF0891538.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKEYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(19612..20448)
                     /locus_tag="KNP54_000610"
     CDS             complement(19612..20448)
                     /locus_tag="KNP54_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBF0891539.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(20936..21499)
                     /locus_tag="KNP54_000611"
     CDS             complement(20936..21499)
                     /locus_tag="KNP54_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891540.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(21597..22526)
                     /gene="glsA"
                     /locus_tag="KNP54_000612"
     CDS             complement(21597..22526)
                     /gene="glsA"
                     /locus_tag="KNP54_000612"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBF0891541.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(23396..25063)
                     /locus_tag="KNP54_000613"
     CDS             complement(23396..25063)
                     /locus_tag="KNP54_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBF0891542.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(25137..25892)
                     /locus_tag="KNP54_000614"
     CDS             complement(25137..25892)
                     /locus_tag="KNP54_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBF0891543.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EILTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(25902..26438)
                     /gene="lepB"
                     /locus_tag="KNP54_000615"
     CDS             complement(25902..26438)
                     /gene="lepB"
                     /locus_tag="KNP54_000615"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBF0891544.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(26604..27140)
                     /gene="lepB"
                     /locus_tag="KNP54_000616"
     CDS             complement(26604..27140)
                     /gene="lepB"
                     /locus_tag="KNP54_000616"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBF0891545.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(27240..28550)
                     /locus_tag="KNP54_000617"
     CDS             complement(27240..28550)
                     /locus_tag="KNP54_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBF0891546.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(28629..29345)
                     /locus_tag="KNP54_000618"
     CDS             complement(28629..29345)
                     /locus_tag="KNP54_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBF0891547.1"
                     /translation="MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            29590..30861
                     /gene="sleC"
                     /locus_tag="KNP54_000619"
     CDS             29590..30861
                     /gene="sleC"
                     /locus_tag="KNP54_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBF0891548.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(31287..31943)
                     /locus_tag="KNP54_000620"
     CDS             complement(31287..31943)
                     /locus_tag="KNP54_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891549.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGVRILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(33055..33465)
                     /locus_tag="KNP54_000621"
     CDS             complement(33055..33465)
                     /locus_tag="KNP54_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891550.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(33681..35063)
                     /locus_tag="KNP54_000622"
     CDS             complement(33681..35063)
                     /locus_tag="KNP54_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBF0891551.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVILRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(35074..35433)
                     /locus_tag="KNP54_000623"
     CDS             complement(35074..35433)
                     /locus_tag="KNP54_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0891552.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(35638..36417)
                     /locus_tag="KNP54_000624"
     CDS             complement(35638..36417)
                     /locus_tag="KNP54_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBF0891553.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
     gene            complement(36878..37489)
                     /locus_tag="KNP54_000625"
     CDS             complement(36878..37489)
                     /locus_tag="KNP54_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBF0891554.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(37581..38570)
                     /locus_tag="KNP54_000626"
     CDS             complement(37581..38570)
                     /locus_tag="KNP54_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBF0891555.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(38637..39500)
                     /locus_tag="KNP54_000627"
     CDS             complement(38637..39500)
                     /locus_tag="KNP54_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBF0891556.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(39606..40202)
                     /locus_tag="KNP54_000628"
     CDS             complement(39606..40202)
                     /locus_tag="KNP54_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBF0891557.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(40242..41045)
                     /locus_tag="KNP54_000629"
     CDS             complement(40242..41045)
                     /locus_tag="KNP54_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBF0891558.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDRTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(41081..41521)
                     /locus_tag="KNP54_000630"
     CDS             complement(41081..41521)
                     /locus_tag="KNP54_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBF0891559.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(41534..43636)
                     /locus_tag="KNP54_000631"
     CDS             complement(41534..43636)
                     /locus_tag="KNP54_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBF0891560.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(43897..45600)
                     /locus_tag="KNP54_000632"
     CDS             complement(43897..45600)
                     /locus_tag="KNP54_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBF0891561.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(45626..46585)
                     /locus_tag="KNP54_000633"
     CDS             complement(45626..46585)
                     /locus_tag="KNP54_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBF0891562.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(46721..47239)
                     /locus_tag="KNP54_000634"
     CDS             complement(46721..47239)
                     /locus_tag="KNP54_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBF0891563.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(47282..47767)
                     /locus_tag="KNP54_000635"
     CDS             complement(47282..47767)
                     /locus_tag="KNP54_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBF0891564.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(47764..48381)
                     /locus_tag="KNP54_000636"
     CDS             complement(47764..48381)
                     /locus_tag="KNP54_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBF0891565.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(48446..48808)
                     /locus_tag="KNP54_000637"
     CDS             complement(48446..48808)
                     /locus_tag="KNP54_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBF0891566.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(49552..50049)
                     /locus_tag="KNP54_000638"
     CDS             complement(49552..50049)
                     /locus_tag="KNP54_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBF0891567.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(50224..51135)
                     /locus_tag="KNP54_000639"
     CDS             complement(50224..51135)
                     /locus_tag="KNP54_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBF0891568.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            52059..52910
                     /locus_tag="KNP54_000640"
     CDS             52059..52910
                     /locus_tag="KNP54_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBF0891569.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            52914..53384
                     /locus_tag="KNP54_000641"
     CDS             52914..53384
                     /locus_tag="KNP54_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891570.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            53397..54707
                     /locus_tag="KNP54_000642"
     CDS             53397..54707
                     /locus_tag="KNP54_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0891571.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            54919..55665
                     /locus_tag="KNP54_000643"
     CDS             54919..55665
                     /locus_tag="KNP54_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0891572.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTDDSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            56027..57568
                     /locus_tag="KNP54_000644"
     CDS             56027..57568
                     /locus_tag="KNP54_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBF0891573.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKASISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            57603..58709
                     /locus_tag="KNP54_000645"
     CDS             57603..58709
                     /locus_tag="KNP54_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBF0891574.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFQGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGEIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(59088..60374)
                     /locus_tag="KNP54_000646"
     CDS             complement(59088..60374)
                     /locus_tag="KNP54_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBF0891575.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(60497..63595)
                     /locus_tag="KNP54_000647"
     CDS             complement(60497..63595)
                     /locus_tag="KNP54_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBF0891576.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVTLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            64321..64479
                     /locus_tag="KNP54_000648"
     CDS             64321..64479
                     /locus_tag="KNP54_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891577.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKKMK"
     gene            complement(64766..65470)
                     /locus_tag="KNP54_000649"
     CDS             complement(64766..65470)
                     /locus_tag="KNP54_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891578.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(65461..67068)
                     /locus_tag="KNP54_000650"
     CDS             complement(65461..67068)
                     /locus_tag="KNP54_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBF0891579.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(67322..68500)
                     /locus_tag="KNP54_000651"
     CDS             complement(67322..68500)
                     /locus_tag="KNP54_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891580.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(68726..69220)
                     /locus_tag="KNP54_000652"
     CDS             complement(68726..69220)
                     /locus_tag="KNP54_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBF0891581.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNIGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(69221..69982)
                     /locus_tag="KNP54_000653"
     CDS             complement(69221..69982)
                     /locus_tag="KNP54_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBF0891582.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            70684..73518
                     /locus_tag="KNP54_000654"
     CDS             70684..73518
                     /locus_tag="KNP54_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0891583.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIMHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            73561..74805
                     /locus_tag="KNP54_000655"
     CDS             73561..74805
                     /locus_tag="KNP54_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBF0891584.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(75220..76962)
                     /locus_tag="KNP54_000656"
     CDS             complement(75220..76962)
                     /locus_tag="KNP54_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891585.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
     gene            complement(76946..77620)
                     /locus_tag="KNP54_000657"
     CDS             complement(76946..77620)
                     /locus_tag="KNP54_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891586.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(77657..78646)
                     /locus_tag="KNP54_000658"
     CDS             complement(77657..78646)
                     /locus_tag="KNP54_000658"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBF0891587.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(78694..79938)
                     /locus_tag="KNP54_000659"
     CDS             complement(78694..79938)
                     /locus_tag="KNP54_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0891588.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            complement(79980..82526)
                     /locus_tag="KNP54_000660"
     CDS             complement(79980..82526)
                     /locus_tag="KNP54_000660"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0891589.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIAVYFSNKMINKLSIVSGIKEN"
     gene            complement(82734..82895)
                     /locus_tag="KNP54_000661"
     CDS             complement(82734..82895)
                     /locus_tag="KNP54_000661"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891590.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            complement(82951..83967)
                     /locus_tag="KNP54_000662"
     CDS             complement(82951..83967)
                     /locus_tag="KNP54_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0891591.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            complement(83964..85262)
                     /locus_tag="KNP54_000663"
     CDS             complement(83964..85262)
                     /locus_tag="KNP54_000663"
                     /inference="COORDINATES: protein
                     motif:HMM:NF015983.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0891592.1"
                     /translation="MIDSEEMIFNVEDLIIYRKNQLVIIYNKKFRKYIKLSEEIYKYF
                     LLGQENKIKIYDFVNYFDDESDKKYIINLIDIMNKNQIFKSNNLNFDMLSNGVAIYFC
                     LTNRCNLFCKHCCVESSSNKKDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIREDFF
                     EIIKYIKQKLPDTKLILSTNGTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRGKG
                     VFNKVISSVNLLKDNGFSNIKLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPTGR
                     GLENKESYLIEDTVLPITIPYILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDGDV
                     YPCPSLIKDDYKMGNIFDNEFVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVNIF
                     CWHCPAILDSVKDNELELDRWCSMMKHNLNTAVWGDEKVN"
     gene            complement(85728..87047)
                     /locus_tag="KNP54_000664"
     CDS             complement(85728..87047)
                     /locus_tag="KNP54_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBF0891593.1"
                     /translation="MLNINVFWIFLPIFSTAIEWIVLKFLLNEFSELRKNRLTLNSSI
                     VIAIMIITMLNTIEFNINIKLFICIFITYVLYKINYVVDKWKSVFISLLYWMLLIGFD
                     SIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIPLLKFIRLKTKINKRDC
                     IYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTVFLLSNLSLVSIIGRIIK
                     DNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNHIICIQNVYGKNEFADK
                     YIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNNIYFLVDINFLECNFIEMPDI
                     CSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKCENTKINEVVLKNNKVI
                     TSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYIPLTRN"
     gene            complement(87041..87169)
                     /locus_tag="KNP54_000665"
     CDS             complement(87041..87169)
                     /locus_tag="KNP54_000665"
                     /inference="COORDINATES: protein motif:HMM:NF016296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891594.1"
                     /translation="MEYIQFICKNTVVINGKDIPVSKYRMANLKKKLTYVLGDVLC"
     gene            complement(87308..88018)
                     /locus_tag="KNP54_000666"
     CDS             complement(87308..88018)
                     /locus_tag="KNP54_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891595.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKKTVVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
BASE COUNT        29765 a        15239 c         9016 g        35147 t
ORIGIN      
        1 ttataaatat tacaataaaa tatttttttc catgatatac cttgataaaa tctctgcttc
       61 tttaagcagt aactttgagt tgaatcatta tagtgattta taacatttat agaaatgctg
      121 ttatagattt atatttaaac actacaaatg gaaatttaac tattataaaa aacaatcatt
      181 agataaaatg attcttacaa caaaagcatt tctattgtag atttattagt aaataataaa
      241 tctacaatag aaaaaactag aagtacagta tcataaaaat ataattaact gtacttctaa
      301 attattgttt ttaaaataaa ttttcattca ttaaaaaata catataaata tttccagact
      361 ccgattcagc aaacttatat aagttcactt tttatttatc atcaattatt ttcatatact
      421 tcttttatct catcttcact taagtcaaaa tcattaaatt tatttaatat gtcatctaat
      481 ttaaaaccat tttttttcaa cattataatt attttataat ctttttcttt tgcaactcta
      541 attgctgtct ctctttcaat ctcttcttta aaatttctac ttttattcat gatataagca
      601 cctcttttca gatttaataa atattcttca ttgctaccta attcttttaa tctatcaagt
      661 gcttttttaa taatagaatc attcttagct ataactctta catctaagtt agaaggatta
      721 ctaataagtt ttccccatag cataattcta tttactatat agtcagattt atgaattttt
      781 ggaagctcta taaaatataa tgcagtttta ctagaataaa tatctggatg cccgtccatt
      841 gttaatctca ggcaatttac ataatcttct atgtgattat attttacatg atttagtata
      901 tgtattccaa tagtttttcc aatttcttta tactctttac cttcttctaa ctttctacca
      961 tgtacacgac taagataata ttcagctctt tccaaataat cgttctcaaa agctctttgc
     1021 atctcaatat ttatatgatt attttcttca tcttcagcca aaatatcaag tttaggtctt
     1081 ttctctccaa tgtaattaat tgttggatca gtttcaactc taattattct ctttatttga
     1141 gtgaacggtt tgatattcct gttagcatat ggagcatctt ttagaatatc atttataaaa
     1201 tttacaagta aatcatattc attatttaaa gtgaacaatg atttaaatac ctcatcatac
     1261 tcaggcttag catatccatc ttcagtcaca acttctccaa cattttcatt agtcaaaatc
     1321 tcttttggaa ttaatgcctt gattttatct aattcatcat tagaaaaact acttctacta
     1381 agtatatcat ttaatttttt ggtccattct ttatcttttt cttcaattat agttcgctta
     1441 tattcttttg atgttttaat aatcttagat ttttcttcta ctttttctat catttcaaca
     1501 cctctctttt tcctcttttg tatttatcat ttcttgaaat taaactaagt cactacctct
     1561 tttaaaagtt cttgctccat aaacactttc ttaaactcta atgtctgtgt atgtacttga
     1621 cattctctct ctatctaaag ttaaataaat taatctatgt atagaggata agtccaaaaa
     1681 taacataaaa cactaattaa tcatttataa agcattaatt aatcactgac aatgctgtta
     1741 ttgtcaccac atagcaccaa catagattct tctattatag ggcaattatc tatgaaaaat
     1801 agactcataa gattagaaaa tgtacttaaa ttttagttca tttaaatatt cattttgaag
     1861 aaagaaattt aactttagac taaaaaggaa atatttcaag aggattaaga aattttctta
     1921 aagggataat aatttttatg aaaatggaac aaatatgaaa ataaagttat gatttttaca
     1981 gccataacct taccaacaag cacttaatta tcactcaaaa aataaacttt tatttaaaga
     2041 atgcacataa atatttccat gttcaaaaca cttctatgat atatttatta ataaatctac
     2101 catacaaaaa actagaggta cattaatcat aaaaatatga ttaactgtac ctctaattat
     2161 actcatcttt tcataaattt aatcactatg catcaacata tcaacatatt gattaaactt
     2221 atcttatata acaatatctt agctactaat ataatatata ttagtcttga ataatacttt
     2281 ctcttgattc aatttctttt gaaatactag ctataaattc atctaattta atactaccta
     2341 tttcaccttt atctcttgat ctaacagaaa cattattatc agctacttct ttttcaccta
     2401 ctattaacat gtatggcact ttttcaagct gagcttctct tatcttaaat ccaatttttt
     2461 cagctctatc atctaattca actcttatac ccttatcaaa taactctttc ttaacttcat
     2521 ttgcataatc cataaattta tcagatatag gaagtatctt aacttgagtt ggagataacc
     2581 aaactgggaa tttaccagca taatgctcta ttaatatacc tataaatctt tctatactac
     2641 caaaagcaac cctatgaatc ataactggtc tatgcttttc accatcttga ccaatataag
     2701 tattatcaaa ttgtcttgga agctgcatat ctaattggat agtaccacat tgccaagttc
     2761 ttcctaaaca atcttttaga tggaagtcta tcttaggacc atagaatgct ccatcaccct
     2821 cattaatagt atatggtaga cctaactctt ctaaagcttc tcttaatcca ttttctgctg
     2881 cttcccactc ttcgtcgctt cccatagagt tctctggtct tgtagataat tctaaattat
     2941 attcaaatcc aaaagttttg tatataccat ctattaagtt agctactcct tttatttcgt
     3001 ccttaatttg ctctggtaac atgaatatat gtgaatcgtc ttgagtaaat gctctaactc
     3061 tcattaatcc ttgtaatgca ccagataact catgtctatg aactctacca agctctgcaa
     3121 ctctcattgg gaaatctcta tatgaatgta gttgagagtt atagtaaatt aatccaccag
     3181 gacagttcat aggttttata gcataatcct catcatctat tttaactgta tacatatttt
     3241 ctttgtaatg ataccagtgt cctgaagtct cccataattt tctatttaat atgattggag
     3301 attctatctc aatatatcca gcttttctgt gtatttctct ccagaatttt aataattcat
     3361 ttttaagttc catacctttt ggtaaaaaca tagggaatcc tggaccttct tcaggtatca
     3421 taaataatcc taattcttta cctaattttc tgtggtctct ctttttagct tcttctagta
     3481 aatgtaagta ctcttctaag tctttgtttt tctcaaaaga agttccatat attctttgaa
     3541 gcatcttatt attttcgtca ccacgccaat atgcacctgc tacactttgt aatttaacag
     3601 cttttacctt tttagtagat ggtaaatgtg gtcctctaca taaatcagta aaatcacctt
     3661 gcttgtagaa agatattatt tcactttcag gtaaatcaga aataagttct accttatagt
     3721 cttctccttg ttctttcata agctctaaag cttcatttct aggaagttca aatctttcta
     3781 tttttaaatc ttctttagct atttttttca tttcagcttc tattttctct aggtcctctg
     3841 gaactaatct atggtctaaa tctatatcat agtagaatcc attttctata cttggtccta
     3901 tagcaagctt tgcttctggg taaagtcttt ttatagcttg agctaatata tgcgctgatg
     3961 tatgtctaaa aacttcctta ccttctttat cttcaaactt aaataaattc aagtcacaat
     4021 cagtatctat aatgtggtcc agacctacaa cctctccgtt cacagacgct gctaccacat
     4081 ttctagctaa tccttcacta atggatttag ctacatccat aacagaaata gcattttcaa
     4141 attcttttat tgagccatct tttaaagcaa ctttaatcat tgttttttcc tccttattga
     4201 aataattttt agattttttg taataaaaaa tcgccccaaa tatgtttggg acgatattaa
     4261 ttcgcggttc cacccaagtt ggcgtataca agtatataca accctcttga tgactataag
     4321 gtcgtcaccc gagcactttc acgtatagta taaatacaaa tactgctaat aagctcagct
     4381 ccaaggtagt tttcaaatag acctattaca tgggctctca gccatagacc caaattctct
     4441 gagaatggtt tctactctac tcttcctctt caacactatg atttttaata tattttcatt
     4501 ataacagata gttatacatc aatcaacatt aatgtaatat attaattacc cattattttt
     4561 catctcaatc agctgtaaac caatattctt atatttttat attaaattaa tctcttgatt
     4621 tatagttata ttataatatt ttcataaatt taaaattttt aaaacgtatc cacatgcatg
     4681 atagatatga ctagataaat actaaaacta atttttatta aaactaactt ctaatttttg
     4741 tactcttttt aggttttgta tacttaaata caatcaatac ttaatatggt taataagtag
     4801 tacagtaaat acttaaatac tattaataag taacacaatc aaataaataa atacaattaa
     4861 tatctaaatg ctattaataa gtaattcact caaataggta aatacaatta atatctaaat
     4921 actattaata agtaattcac tcaaataggt aaatacaatt aatatctaaa tgctattaat
     4981 aagtaattta ctcaaatagg taaatacaat taatatctaa atgttattaa taagtaattc
     5041 actcaaatag gtaaatataa ttagtactta aataaatgct acttctcata tatttaaata
     5101 aacatagtaa ttaacccttg agctatacct attaaaaacc ctaagacaag ccccaaaaac
     5161 tctatatgtt ttaattcttt cttagctatt cttattatta tctcttccaa ttcatataaa
     5221 tctagttcat taatcttatc ttcgaccatt ttttgtatat ctatacgttc atttgcttta
     5281 tttattatat ttttactcaa ttcatctata ctttgcttaa cttcagactc aattatctct
     5341 cctagataat cttgtatcat gttttttata ccactcggga taaatgaaac tttctcatgt
     5401 attataattt ttacccttgc ttttatgtat cttacaactt cttccttatc ttcgtcagta
     5461 atgatatttg caagtatttc gtccatagaa agaaattctt cttgaattat ttctcctaca
     5521 tttgctgcta tttctgctct tctctttggt ataagaccta ctatttctat atttaaaata
     5581 ggtattttaa taggctctat tggtctaaat atcagtctta tagcaactac attcgtaaca
     5641 taacctataa atccaccaat aacagctaat atcagtatcc taattaaatt atccattata
     5701 aaattactcc ttatcaattg tatatttgcc agctatattg cattaatcaa gtagatattc
     5761 tttatactta ataactctag ttatactata gctttatata caattataag tcttttgtgt
     5821 cgatttaaaa agaatttttt taattttata tggatagctt ttatatgctt agattctagt
     5881 tttccataat tatactaact ttattttcaa aaattgcttc tacagtatct ataatttcct
     5941 ttgagcaatt attatttaac aaatccaata tttctatttt tttgggacat agagttaata
     6001 aggtacttat taaaaagtcc tcataattta aattttctct tattaccata tttataattt
     6061 cttcatcatc tatactgtct atcttatttc catttttatc gtataaaaca aatgtattat
     6121 cttccattat atgaacttta agcaaatcaa tcttttcttc ttgagtatct ataaagtatt
     6181 ttaaaactct tataaattca tcttggtctt tctttattaa atactcctca actgcaatat
     6241 cacctatagc agaaatatat ttcataaatt ctctcattct aaatctaata aaaccttcta
     6301 catttataaa atcattttct tctatataat ttctcaccct agtaaatact gtttctctca
     6361 taaaaatctc ttttttagca aatatgttca gtgaatatat gtatatatta tttttatctt
     6421 caggatatgt acgcccatag cattttagaa tgtattcttt caaaagtttc tctttcatta
     6481 tacttattat catactagtt atttccgttg atatctcatc aatatttaaa gctctttgtt
     6541 cagctttagt accattaagt atttttttat ttaacacttc ttgctttgca gaatctatca
     6601 ctacttctac aatgtcattc gtatatatta atctatcgtt tacattatta ttcctcaaaa
     6661 atttcatgga agaaatatta tccttctcaa ccaaagttat cgctcctttc ttgtcatgag
     6721 aggaactata gaacctatat ctagtaaatt ttcacagcta agtgtaacta tctccttgtt
     6781 tttactttct acaaaacttt ttatacgttc atagtcagga tgttttttaa catctccaca
     6841 aaaagctagt ttatccttag aaatcaaccc tgtacatcca cctataaatc cataattcat
     6901 ctcaaataaa tttatgtgac ctttttctat caataaacac tctatttctg tattcttcat
     6961 acttttccaa atacctttat ctgatgttat tatagacgtt ctatctacta tacagattga
     7021 gcatttagaa tagccctgct ctatatttat ctttttaagt ttattatttt caatataatc
     7081 taatattgct ttgtcagtat acttaaaatt gtgtatagca tagtcaccaa ctatcgcaat
     7141 attgtaaggt atatcataag ggtatctatt taataaatta gcttctccct taattatatt
     7201 aaatttatat ctacttaata actctttgta ttgattatat acattcggcg caacaattat
     7261 atctcctttt cctaaattac aaatacatat atccgggtga tattttatgc tttcatataa
     7321 ttctttacat tctattgttt ttattatctc tatatttctt aattttaatt cattttccat
     7381 tagataacta attcttttgt ccaccaaagc tagacacaaa tcgtcatcta gtataaatgg
     7441 ttctcttgta aattccattt tttactcctt tttctttttt ttgataaatt ttttatgtga
     7501 atataaataa agtgtgtagc agaatttttc tgcccacaca cttattgtta taattttata
     7561 tagttattct aagcttaatt agtatagctt tgtacagttg gttcaaattt aataaatata
     7621 tctttttatc actaatctaa acttaagcag tatattccgt acagttagca caaatttaat
     7681 aaatatatct ttttattgct aatctaaact caatcaatat attttgtaca gttagactaa
     7741 atttaataaa tatatccttt tatcaccaat ctaaacttaa gcagtatatt ccatactgtt
     7801 aacacaaatt taataaatat atctttttat cactaatcta aacttaatca atatattttg
     7861 tacagttagc acaaatttaa taaatatatc tttttattgc taatctaaac ttaagcaata
     7921 tatttttata atcttctaca tcaataatta atatgtatct ttcactttgt tatactcttt
     7981 ttttatgtat tccaaaacat ctggtggtat atttctactg ctctttgaag tcaagccaag
     8041 ttccccatct tttattttaa attccattac tttacttccc ttaaaaccat cttttgcaac
     8101 gttctttatc agttcatata caggttgttc tacatctttt ataattgaac ttattacatt
     8161 atctggagcc atatcgtatt ggtctttatt aatagctata actttaccac cattttctct
     8221 tgctacctga atagctcttt tactatcatc ttctgtagct gaaaatacaa catctctatc
     8281 agaatctctc atttcctttg caatagttct agctgattca gggttttcaa atatatttga
     8341 atacttaact agtaactcag catctttatt tgaagtttta agcccctttc taaatccaga
     8401 ttcatactta tctctactag aaccctcaac tcctcctata aaaccgactt tcccagtatc
     8461 agtcatttta cctgcaataa gtcctgctaa atatccagta acattatctt gaaatgatac
     8521 agaaattaca ttagctggct gaactttata agtatagtca actattgcaa attgctgttt
     8581 gggatattta gtagcagctt ctttaattgg ctctgcaaat ctggctccaa ctgctattat
     8641 aaaatctggt tcatacttat gcagtttttc tatactctct ttaaaacttt tagaagtctt
     8701 tggtttttca agttttatcc taacatcaaa atcttcgtca gcccttttta aggctgatag
     8761 tacattgtta ttatatgatt cgttatttaa gttttcggta tctaacaata ctccaatagt
     8821 ttttcttaca tatgaatcat cttctgtgtc atcttcttta ttcttacttt tactatttga
     8881 tttatccttt tctgctgaag ttagcaaact tttagactca ctctgtttcg atttagcact
     8941 atctatatta gaattattct tatttacttt atcaaaccca aaatcaaaat tacatatagc
     9001 taatataaaa attgtaaaaa ctactacaaa gcaagccatc aatatccttt ttattttcac
     9061 aaaattcact ccctgattta gataggtctg acctacctct gcatatgtct ttctatatat
     9121 gtctattata acatccaatt cacctcataa ctaaactcat aagtattctt ggatattata
     9181 gtagattatt tattgttctt attaacatat tctaacacat ctggaggaat attttgagaa
     9241 ctattttggg caagtccagt acttccagac ttaactgtgt tttctataac ctttccgcct
     9301 ttataatttc cttttacaaa actttgtatc agattataag taggattctc aaaatctttt
     9361 acaatagaac ttataacatt ttctggagct aactcatgtt ggtctttatt cgttgctata
     9421 acttttttat tttttgccct tactgcatct attacagctt ttgaatcatc ttcagtagta
     9481 gaaaaaataa tatccactcc attatccatc atttttttag ctatagattc tactgatttg
     9541 ctatctttaa aaacatctgc atactcaact gaaatatcct ttatactact attagaaaat
     9601 ttaacaccct ctctaaaacc tgattcaaat ttatctctac tagaactctt tgttcctcct
     9661 ataaaaccaa ccttatcgct ttcagtcatt tttccagcaa ttaatccagc taggtatcca
     9721 gatttattat cttcataaga aattgaagtt atattagaag gttgcttgtc atactcatag
     9781 tctataattg caaattgttg ctttggatat ttcttggcta ccatctccaa tggttttgca
     9841 aatctagctc ctacagctat aattaaatcg taattgtcat tacataaaat atctatacta
     9901 ttagaaaaag ttgaggaatc atctgattcc actttgtttg tatctatatt aagtttcttt
     9961 tgagcattgt ttaatgctaa taaagctgaa ttattcatag cttcattatt tgttccttca
    10021 atatctagta tcattgatac agattttttt gaattacttt tatcgcttat atcactttta
    10081 ttatctttgc tagagctagg attattactt gggttattag cacacccaac caacattcca
    10141 gctatcattg ctacagttaa catcaatatc aatattcttt tgaaacgcat taaatttcac
    10201 tcctcataca tttacgatat ttttatatcc tatttacttt tacatcctat ttataatttt
    10261 tttatataca atttacaagt acattttgaa atttttttaa taaatcttac tataaaaaag
    10321 tgtgcaatag attcttatct atttacacac ttccctacaa actaaatcta atatatcaac
    10381 acttaatttc atccaaaata aatccaattt aacatctcaa caattaatat tctatcctaa
    10441 tttaataaaa aaataaataa tgtcatccaa aaatatatta tttatttttt aagcatatga
    10501 taccagtaac accaggacca gcatgtgcac ctatacacac accaatttgg aaaaatctaa
    10561 tttctttagg tcttaattca tcttgcataa ccttagataa ttgttctttt tccttaaaat
    10621 catcactata tcctatatac acaatttggt ctgataaatc atcaccacaa tttgatttta
    10681 tcaattccat catcttagaa attacattct tctttcctct tacttgagat atttgcgaaa
    10741 ctaatccatc tcttatttca agaatcggtt ttatatttaa tatacttcct attgctgcct
    10801 tagtagatga tattctacct cccttttgta aatattccaa tgtatctact gaaaatataa
    10861 caaaagcctt ctcttttaat tcatccaaaa caggcaatat ttcagcaaca gactttcctt
    10921 cacttgcaag ttctcctgct tttattacaa gtaaaccagt tcccatacaa agcaagttag
    10981 agtcatatgt atatatttta ccatctacat cattctttgc cattacagca ctttgatacg
    11041 tacctgtagc tgtggcagac cctgctatat aaagtatctc tctatcctca tttgtatatt
    11101 tctcaaaaat ttccttaaat tgggcataag tagcttgaga agtttttgga tatacatttt
    11161 cttctctaag ccttttataa aattcatctc cagatatatc aattctatcc ttgtattctc
    11221 tttcctccag tataactgtt aatgaaacta tatctatatc atatttatct aacaaatctt
    11281 ttggcacgtc cgataaactg tcacagatta tctttagatt tttcattaag tatgctcctt
    11341 tctcatttag gcttgttgaa actacctcat atttgggtat cctatttgtc ttaaagcctc
    11401 gtacactaca atagcaactg aatttgataa atttaatgac ctagcttttt caacatccaa
    11461 cataggcact ctaatacaag tatccatatt tgctttcaac aaaggttctg gtaatccctt
    11521 tgtttctttc ccaaatacta taaaacaatt ttcttcatat ttcacatctg aatgtgactg
    11581 tttagccttt gttgtagaaa aaaagtattt actatttgga tacttttctt gtaattcttc
    11641 aaagctatcg taatattgta tatcagctat atcccaatag tcaagcccac atctttttag
    11701 gtgtttatca tccaatgaaa aacccagtgg ttttactaaa tgtaaagttg aacctgttgc
    11761 tgcacaggtt cttattatat ttcctgtatt ttgaggtatt tctggttcta ctaatactat
    11821 atttaatgac attttaatcc tccctaagta tcgcttttat ttatcaaatt ttattttata
    11881 aacagaataa caataatatt atactattat ataaaataat gttaataata atttttattt
    11941 catgtatata atagtttttt atctaacatt ttcacaagta ttattatatc agaaaatccc
    12001 tcttgtacaa cttactttct aaaagttatt tcgtttcatt aagttcttta taataattac
    12061 aatcttcttt tattgggcaa cttgcacatt ctggatttct agctttacac attcttcttc
    12121 catgaaaaat taatacatga tgtgagtgtg accatctttc ttttggtata gcttccataa
    12181 gtgcaaattc tgttttttga ggatttggct cgtccactat tcctattcta ttgctaactc
    12241 taaatacatg agtatctaca gctattgctg gatgattaaa agcgttacta agtacaaccc
    12301 ctgccgtttt tcttccaaca ccaggtaatt ttataagctt ttctaagcta tcaggtactt
    12361 caccatcata taattcacat agctgttcag atgtatcctt tattttttga gacttgcttt
    12421 tgtaaagacc acaactcttt atctctttac taatttcttc aatgctcaaa ttagcaaagt
    12481 ctctagctgt gttgtacttt ttaaacaact ctgaagtaac tttattcact cttacatcag
    12541 tacattgtgc tgataaaata gttgctatta aaagttcaaa ggctgtccca taatttaact
    12601 cacatttagc atctggatac aatttttcta actcgtctaa aatcttattt acgtcttttt
    12661 catttgctga ctcattttta attttagact tacttttagt ttctttactt gttttttgtg
    12721 tagccttatt agaactactc ttctttgttt ttttctccgt ttcacctttt ttagtacttt
    12781 ttttacttac tttgatactt tttttatctt cttcaatatc cataaaattc tctatatctt
    12841 tctcatcaat tatctcatct tttttaccaa tcattttatc tattcctttt tcatttatct
    12901 cttccttctc aattatatct ttcttattca ttcctttttt atttatctct tccttctcaa
    12961 ttatatcttt cttattcatt ccttttttat ttatctcttc cttctcaatt atatctttct
    13021 tatctattcc ttttttattt atctcttcct tctcaattat atctttctta tctattcctt
    13081 ttttatttat ctcttccttc tcaattatat ttttcttatc cattcctttt ttatttatct
    13141 cttcttccaa aattacatct ttttcattta tctcttttag atttacattt ttcataatta
    13201 tcccccttca aaataccaat ttataaaacg ctatttataa atagtttaat catatcaaca
    13261 aaaaaataaa catcaatata taaaacatac aaaataagaa tttaatttat atatatttac
    13321 aaaaaaagca aaaacctatt aaagttcttg ctttttatta tacataaata cccattaaat
    13381 tctataataa acttattctt ttgacacagt ttgtatcttg ctgaaagata ttaatttttc
    13441 ttttaccaat ttctttattt cttcaaattt aacatctgtc aatatctcta tagcctcttc
    13501 tactctttca acagtatata tcttaaattt tccatctcgc actgcatcat taacttcatc
    13561 tgataaaacg agatttcttt gattttttct aggaattatg acgccttgct caccatttaa
    13621 ccctttagtt ttacatatag aataaaatcc ttctatcttt tcacttatac caccaactac
    13681 ttgtatatca cccttttgat ttatagaacc tgtaacagca atattttgtt taattgatac
    13741 tccactaaga gatgataata gtacatataa ttctgcagaa gatgcactat ctccatctat
    13801 tccaccataa ttttgttcaa aacaaacata tgcatttagt gacaatagta aatcctgtgc
    13861 aaaattctca gaaagatagc cacctaatat aagtactcct ttgttatgta tagagccact
    13921 catatttact tctctttcta tatttactat gcctttactt cctgggctag tggtcgctgt
    13981 aatccttgaa gctctaccaa aagagtattc tcctgtactt aagactgaca aaccatttat
    14041 cactcctact tttcttccct ctgtttctat tagagtaaat ccattttcaa ttgattcatc
    14101 catatgtgtt tccactctat tgattctttt tctcttttca cttattgctt ttttaacatc
    14161 acactgctct gtatactccg aatttctaaa ctctgcataa gcacttcctt ctattacaac
    14221 ttccattatt ttattaaact tagttgataa tttttctaaa tcaccagata atctagtgct
    14281 aaatttaata acctcttcaa ctgctgattt agtaaaatgc cttaaattat tcttatcaca
    14341 ttggtatgct ataaatcttg ctattccttc ttcattatct tcatttttat ccatttcact
    14401 atcaaagtct acaaatactt taaaatattt ttcaaaatct tcatcatatc tatataaaat
    14461 atcatatata tagtggcttc caatcagtac taatttaaca tccaatggca tattttctgg
    14521 tttaattgct gtttgtgttt ccaatattac ttttttagtc tgcaaagtct ttttaagaat
    14581 ttcccaagac attgtatatt ttagtaattg gtctgcataa agtactaaat aaccaccatt
    14641 agccctatga aatgctcctg ataatagttt tgtgaaatca gtctttatat ttccatttgc
    14701 ataatcatac tctgcctttc caaatagatt tgctggactt gggtttatct ctactacaac
    14761 aggtgctgat tctttattct ttgagcttcc attgtctaca aataggttaa ttttatattt
    14821 aataaaatgc tctttatcat acttatcttt taactcctct tcatctaaat agaataaata
    14881 catatattct attatatctt tctttatatt ttccagataa gtttgaatct tatcataatt
    14941 ttcatatttt tcacacaatc tcttgatatg aggttctact acaagtttag ctatctcttc
    15001 ttcaagctct aacactgctt tttcagctat ttcttctaag tttctaattt tatatacgac
    15061 ctgtatcgcc atattttcta gttctctttt agctttgtaa aactcttcat cagactcatc
    15121 actttcatct tcctcttctt tcaaagggat aaaaactatt cccattttac tctgttttaa
    15181 tttaaatcct ttttcttctc catatttttt aatttgcttc aaaagcatat ctttttctat
    15241 ttcatattca tccagaagtt tatttttttc tatttcaaaa ttttcacttt caaacgcatt
    15301 tttaaaatct tctaaaagac tttcaattaa tttctccata tctttcttaa gttctcttcc
    15361 aaaccccttt tctaattcaa ctataatagg ctctctaggg ttttcaaaat tatatatata
    15421 acaccaatct ttatgcgtat tttttttgga tgcatactca tttaaaacct ttaaggcata
    15481 agtactttta ccagttccag gttcaccagc tatatatatg ttgtacgctg gattatttat
    15541 tttcaaccct aattccatag cttctacagc tctttcttga cccaatatat aatctagtgg
    15601 atttatttca gatgtattat tatatttcaa tattccccca cctccccata tttaacttta
    15661 atgatataat atgactttta cacaacaagt gttaaagtaa atacacatta aagtatatga
    15721 aacagactct tattattagt catcatactt atctaaaatt atttccatat ttctctttat
    15781 tatatttctt cctctccagc taaaagctct atctccatat ttccttttaa attctttatt
    15841 tgaaatattt tgtatctcat cataattcaa ataatctatt atattttctt taaattccaa
    15901 aatatgagtt gttggtattt caacattatg tggacatact tcttgacaaa tatcgcatcc
    15961 aaataccttt ttgccattct ttaaaacaac tttttctttc tctgacaaat ctcctttttt
    16021 ttgagttata tatgataaac attttttggg gttcatatca taatttccca atatagcatt
    16081 tcccggacaa tattttacac actttccaca tttaaaacaa cttttttcta gtggtttatc
    16141 ttcttcaaat ttataattat ttactatata ccctataaat acgtaagaac catattcatc
    16201 agttatgata ttattattta ttccaaaata tcctattcct gataaataag ctaaatacct
    16261 gtcaactaat ggtccattat cagcaaataa cttgtattta aaatctgtta ctgttttaga
    16321 aatataatca caaatttgtt gtaaaaagtc ctttactaca atgtgataat cctttccatg
    16381 acaatatttt gataaatttg aatttttatt cttttcttgt ctatttatat gatatggaaa
    16441 tgcacagact attatagagt tagcatcctt cattatatgt cttgggttaa ttctgttctc
    16501 aattattggt tcttccatac cagttaaata acctttttgt tgtctgtcct taagtatctt
    16561 ttctaaatta tcatacttat ctacccctgc tactcctaca cagtttaatc ctattaaatt
    16621 acaaaatgct tttaattcct tattatccat aaaattattc ctttttaatc taattgactt
    16681 tttaaattta tttaattttt ttagtctttt taaccttttc tagctactaa ctcttttaaa
    16741 tacttaatct ttttagctat tcaattttct tacctactta aatcttttag atacttcgtc
    16801 tttttaccta tttaattttt tacctactaa cgcttttaga tacttaatct ttttatctat
    16861 ttagtttttt acctactaac tcttttagat acttcatctt ttttatttac taactctttt
    16921 agatacttcg tctttttcat ttacttattt aactttttta tctacttaac tcctttaaat
    16981 aattagtctt tttatctatt taattatttt acctactaac tcttttgaat acttagtctt
    17041 ttttatttat ttaatttttt tatctactaa cgcttttaga tacttaatct ttttatctat
    17101 ttaatttttt tatctactaa ctcctttata tacttagcct ttttcattta cttatttaac
    17161 tactaactct tttagatact tagccttttt catttactta tttaactttt ttacctactt
    17221 aactctttta gatacttagc ctttttaatc tattcaacct tttttaccca cttaaccttc
    17281 ttacctttta atataaactc taaaacttca aatatcatta gttatatttt gacattcttt
    17341 ctatagttaa gcaaaaagat tgattttttc ttataattaa tatcccattt acattgccat
    17401 ttattaaatc tttacttgac ttatatggat ttctttttac tctctttact aaactatact
    17461 tattaatatt atgaaggtct tataatagac taatatgaat atgtccatca tatatcaaat
    17521 tttaaaattt gtaagcaaaa tacttatctt atattactac atctaaagtg gaaaatttta
    17581 caaaaaagct ctgtaaaaac actttaaata acaatttgct tttaaatcat atacagatta
    17641 taataaatac tgtataagga tggtgaaaaa tttgattaaa ataacaattc caggtagacc
    17701 tattagtaaa tctaatttta agcttcataa cataaatggt caagcatgga tgccttcaaa
    17761 gggaaaatat tctaagtatc ttgcatacga aaacatgatt gcaggtttta taaaccaaca
    17821 gtatcaaggg gaaactgtcg aagaaaatct aataacagtc ttgaaattat tcttcccaaa
    17881 taagagaatg ggggatttac ataattatcc aaaaagtatt tgtgatggta ttgaaaaaag
    17941 tggaataata aaaaatgata aacaacttaa gccagtactt ttatttgatt ttatagataa
    18001 agataaccct agggttgaaa ttgaacttta tccagtatct aaatacgata tatcctataa
    18061 tatttttgaa aaataaagat tttatgtgtt attcgacatt atattgatac tccagtattt
    18121 gaaactatac taatacaaca ataataattg tgttatgtct atactcaaac aaatgttttt
    18181 aaaaagcatt aagtaaatat ttaataagta ttaaacaaat attaaattta tataatagct
    18241 ataactatgt aaatttaata tttgtatata agaccacatc taataaaaag aaatcggagt
    18301 aaatttaata caccgatttc aataaataaa atctatccta gcttttcaac aacagtctta
    18361 agcatttctc ttataggaag ttcatatgga catctactct cgcaaagccc acagtcaata
    18421 cactcagtag gtttaacatc cataacctca tatttttctt tagcccactc ttttaatcca
    18481 tatctagtat aataaccttc acataaaaaa ctcaatggta tatttattcc tacagcacaa
    18541 ggcatacaat attcgcatct tctacagaat tttttaccta aagaatttct tatttcttca
    18601 atttccttat tatctttttc atctagcaca agattttcaa gtacagcgac attttgtcta
    18661 acctgttcaa cactctccat acctggtata actacatcta tgtactcttt agatagtata
    18721 tatttaatag ccagtgttgc attgtctaaa gcacctccag ctaaaggttt cattactatt
    18781 atcccaattc ctttttcatg agctttttta aacacttcat ctgcttgtcc ttcaactata
    18841 ttataaggga attgtatagt gtcaaatttt ccatcttcta tagctttttc tatagtattt
    18901 aaattgtgac tagttatacc aatatgtttt atcttacctt gctcctttgc ctctaaaagg
    18961 gcactataag ccattttatc tttaaaaaga ttatcatact cctcttcttt aacattatgg
    19021 aattgatata aatctataaa atcagtttta aaattattta aacttatttc aacatctctc
    19081 ttcattgaat cataatctct ggacatactt ttagtagcta agaaaaattt atctcttttt
    19141 ccttcaatgg caattccgat tgcttcctca cttattgtat accctcttgc actgtcaata
    19201 aagtttattc cttgtttttc taactcattt ataactaagt tagtatcatc ttgagtaatc
    19261 ctttgtattg gaatgccccc aaagccaact ctctttattt tcatgttagt attgcctaaa
    19321 tttctcatat ctttccccac ctaactttta ataatttttt atataatata aatatgtcac
    19381 ctttaattat acaacaaatt atgagaatct ttgcaatgta tttacatact attcataata
    19441 taattatatt ttatatcagt ctattcataa tataatcata ctttataccc agttaatttg
    19501 tatacaattt tcgttattcc tatccattaa tttaaattat cacatttcat gattgtatct
    19561 ccaccctaat tatgttgagg gtggagtatt tcacatattt ttaataaagg tttatttact
    19621 agatagtatt tcttttatca ttttaagctc tctcttgtga ccttcatcat caaaaggagt
    19681 ttctaagaaa aatggtaaat gttttagact aggatgttcc ataaaatcaa ttaatgcttt
    19741 taatcctatc tttccttccc ctataggagc atgtctgtct tttttgtctc caaatggcat
    19801 catactatca tttagatgga cagttttcaa tctttctatg cctataacct tatcaaattc
    19861 ttccaaaacc ccatctaaat cattcactat atcataacca gctgaaaaaa tatgacatgt
    19921 atcaagacac acacctattt tttctttatg ctcaattttg tctattatac tttttaattg
    19981 ctcaaattta aaacctattt cagttccctt tcccgacata gtttcaagaa gtatagttat
    20041 attttcatca ccctttatgg cattgttcaa tccttttact attctatcta tgccaaaatc
    20101 tacaccacca cctacatgac ttccaggatg aaaacacatg tattcaattc ctaatgagtc
    20161 catccttctt atatcctcat ctatcaccct tgttgcaaat tcgtatacat catcctttgt
    20221 accacccaga ttcatagtat atggtgcatg tgcaagcagt ggtgcaaaat tattttcttt
    20281 tctaatttct tgaaatttaa ttatatcttt ttcatcaaat tctttagcat ttcctcctct
    20341 tggatttcta ctaaaaaatt gaaatgtatt tgcaccaata tatacagctg tctcagccgc
    20401 attagcaaat ccttttgcta ttgaaagatg tgttcctaat ttaatcatat taatctcctt
    20461 ttatttgtac tactacttgt actcaatttt aattttgaac tactccacct taactacatt
    20521 tagccaacat atgaagatgg agattcctat ttgatagtac tttttcacta aaaattcgta
    20581 agctctaagg gatgttctat cccaactaat ctcattcctc ttttaacata tttctagcat
    20641 tgatttaatt tatattaatt tttaatttta atatttacac tttaattata cccattttaa
    20701 tcaatttcaa atattataat cttacatact ttgtatatta tctaagcact tcttagatag
    20761 tgtatacatc ttacactata catattattt acaaatacaa taggtataaa aaaacaaaaa
    20821 aatagagatt aaaaatcatt gttttaccca taccaaaaac tattttttga ttattaagta
    20881 aattttgatg ttcaatctct aatattatat ctttaattaa tccataatta attctctaac
    20941 taggacattc ctcctcaaga gtaggaacta taaccatagc tatatcatac ttagaacctt
    21001 caacattgtg ttgtctttta tttaaaattt catctatctt tgacttcata gtgtcactaa
    21061 gttcaactaa ttcatcatga gtaagagaaa tatcatgata atcaactata ttttcatttt
    21121 ctaaaacatc ttcctctgct gccttataaa aaacttcact catattttca aattttgata
    21181 tgtacaattc ttctttttct tccccattgt ctaaagaaaa attaagtatc ctattcccta
    21241 taaccacatt ttttgcactt ggataatagt acttttccac aatccccgac tttatttttt
    21301 cctcaactaa ttctaaaata ccaactttgt ataacatttt tatatggtag tttatttttg
    21361 catgaggttc ttccaataat tgagataatt gttttgctga caatggcgat ttgtcaaatg
    21421 cttttagaat atctattcta cgtggatgcg caatagcctt tatgcactcc aaatctcgta
    21481 ataccaatac ctctttcatt gacccctcct aaaaaattta tttaattcat atttctttac
    21541 aatttaatta tatattaaat tatatgttgt tgtcaaaaaa atcctttctt aatattttaa
    21601 aaaatattta atttgagttt atttgacaac tcctctaaaa ctttaactcc tgcgacgctg
    21661 ttaccttttt tgtcaagcgc aggtccataa acaccaatcc ccatgcgtcc cggcacagaa
    21721 gccattatac cacccccaac tccagatttt gcaggaatgc caactttaat agcaaattcc
    21781 ccagaagcat catacattcc acaagtcatc ataaatgtct tgacaatcct agaaaccatt
    21841 tcactcatta aatgctcacc attttctata tctactccat aatttgcaag atttattcca
    21901 attctcgcta aatctacaga atctatctca attgagcatt gtttaaaata aaggtctaga
    21961 acatcttcta cattccctct gataaatcca tcacttttca ataagtaagc catagctctg
    22021 tttctatctc cagtcatttt ttcagactta tagacatcat agtttattcc tatattatca
    22081 ttttttgcta actttctaaa gaaactaagc attctttctt ctttttcttc taaacaactc
    22141 ccatttataa gggaagtggt tactatagcc cctgcattta tcattggatt acagggtttt
    22201 tttgtgtcat taatttcaag tttcattatt gaattaaatg ggtccccact tggctccatt
    22261 ccaacgtttg aaaaaacgtc ttcccaatca ttatccataa gtgccatagc aagcacaatt
    22321 ggttttgaaa tactttgtat agtaaacttt gtgctacagt ttccagcact ataaagatta
    22381 ttttcgctat ctatgataca aattcctaaa tcatttcttc tagcgttttt taattctggt
    22441 atgtaactag cgacttgtcc ataattagta tacttcttat tagaacttat aatttctttt
    22501 aataatgtct catctaacgt attcatatgc acctcttata ttatgttata tattctattt
    22561 tagcacaagt ttatactata ataaaacaat gttaaaaaaa attatacttt aaaattattt
    22621 tctacaagaa tcaattcatt tttcaaacaa tttaaatagt ttaaatagct taataattta
    22681 ataatttaac aacctagcaa tttagtaatc taataatcca gtaatttaac aacctaataa
    22741 tttagcaatc taataatcta actatctaat aatccagtaa cttaacaacc tagtaattta
    22801 gtaattcaac aatctaacaa ttcaataatt taacaattta acaacctagt aatctaacta
    22861 tctaataatc cagtaactta acaacctagt aatttagtaa ttcaacaatc taataattca
    22921 ataatttaac aacctagtaa tctaactatc taaataatcc agtaacttaa caacctagta
    22981 atttagtaat tcaacaacct aataattcaa taatttaaca acctagtaat ttagcaatcc
    23041 agcaatctaa taatccagta atttaaattt ttataacacc aaaaatttct aacccaacac
    23101 cttttactct tttactcttt tactctttta ctcttttact cttttactct tttactcttt
    23161 tactctttta aaaaataatc acataaatta acaaaatatt aaacaaaaaa gtaaaattta
    23221 aaataaaaag cttgcttcat acaaaagtat aaaacaagcc tttttatata tcaactcaaa
    23281 ctttaaaatc tgtatcaatt taattctcca ctttacactt aatatactta acataaacca
    23341 ataacactac ttgctatgcc atttaatctt cataaaacaa tctataatac acacattaat
    23401 caactatttt acttcctcca ataaattccc taagaattga aatacctggt atgtcagaag
    23461 tatcgtccaa ttcaacaaaa tactgcaaaa actttagtaa tctagtagct tcaatatgtg
    23521 caggattatc ttcctttatc tcttccaaca aaggtttcgc aaatcgtttt aaaactgcca
    23581 attcatatac acaagcagag ttaaatatag catctgcctc ctcttggtac gggaatatat
    23641 tcttcttttc tcctcttcta actgatgccc attgtaaaat agtattatca gcactatatc
    23701 ctctaaaatt atagtctcta acaattcttc ttatcattct caaatcagca gtagggattc
    23761 gattatggtc atccaaattt atttgagtaa gggcacttat gtatatctta aatttatctt
    23821 catctggtat agatgatgtt aaaataggat ttagcccatg tataccttct aatataattg
    23881 gctgatttga atctatcttt atctttttac cagtgtattc tctcttacct tctttaaaat
    23941 tgaatcttat atcatcaatt tcttcaccag ctaaaagttt ctttaagtct aagttaaact
    24001 tctctaaatc tattgcataa attgattcaa aatcataatt tccatattca tctaaaggag
    24061 tatgttttct atctataaaa taatcatcta aagaaattga aataggattt aaattattta
    24121 ctctaagatg tattgataat ctgtgagcaa aacttgtttt tccagatgaa gatggagctg
    24181 ctattaaaac tactctctta ttgccatcct ttatcatatc cgctatttgg gataacttct
    24241 tttcatgcaa tgcttcaaat gtccttatta tatctccata ttcattgttt tctattattt
    24301 tattaagaga tactaccttg tcaattccca taagtcttga ccattcttct gcttcataat
    24361 atacacttga tagcttaggt tgaggtacaa atttcatagg aagagtctta tcttcttcac
    24421 taggtcctaa aattataacg cctccattat aaagcttaat atcaaatgat tttatataac
    24481 cagttgatgg caacatataa ccataaaaat ggtctatata gtttctacac ttatatactt
    24541 tagcactatc atactctttg tatttcaaaa gctctgcctt ttcatacatt tcattatttt
    24601 caaagataga aatagcttca tttcttgtaa cttcaatttt ttctataaca taatcgttgt
    24661 ttactatctc tttcatcttg ttttttatat tttcaacatc tgcttcttta agctttctat
    24721 ctatatgaac ttcacaatat agcccatctg atagtgaatg ttctattgta actctgctat
    24781 cccaaaagat ttctctacat gccattacaa atataaatga catgactcta aagtaaactc
    24841 tctctccatc ttcattagta gtatctaaaa aatttatctc acaatccttc ttaactctac
    24901 aatttagctc ttttagttta ttgtctacaa ctgcaagtgt tatataaccc ttatgctcat
    24961 cacaaaattc ttttgctata tctcccaatc tgattccagg ggaattttct tctaatgaat
    25021 attccttatc ttttccttct atttttaagt ttattttttt cacttcaaca tctccttcct
    25081 tttgatgaat ataaatttta attaatgagg catatcaaca agataaagag aggtatttaa
    25141 ccctctccta caatattatt caatttactt atagtatctt caatgtcttc gtaatttatt
    25201 tctaatacta aatattctgc atctaatgtt aagatctctt taatcccctc ttcagataaa
    25261 attcctcttc ctataccaac atgtgtatca ttgataccat cattatcact taagtgtatc
    25321 agtcttattt tatcctttaa gttctttaca taagcatcct catcaattaa acagtgtcca
    25381 gtatcgtaac aaaaacaaat cttagaattt ttaatcctct taaatatata ttcaaaatca
    25441 taagatatat ttccaatatt tgaaaaatcc ccaccttttg aataagtatt ctctatacat
    25501 acatatgaat ttgtatttaa tttatctaaa aaatccacac tatttcctaa atatttgtct
    25561 ctattctttc taactctatt tgtcataaca tatcccaaat gaaggttaaa ataccttaaa
    25621 tcaaatcctt ttagttcaaa ttctatcttc tcaataaaat ttatccatga atttcgtata
    25681 tactctatgt tttcgcaagt atttaattcc ataggcaaat gtatccctat agataatcct
    25741 aacttagaaa ttctctcttt atatttacat aactcactac attcagatat attgtcaatt
    25801 ccaatctcta aatgagttat ttgctttata ctctcacaaa tgtttaaagc ctcctcaata
    25861 ttaaacaata aggacgctat accaactgcc atacaaatca cctactcaaa aatacctata
    25921 tctgtaaaag gaaatactct taaaataact tttcctttaa tattttcttc atctactaat
    25981 cccacttctt tatatctact gtctaaacta acttctctat tgtctcccat cgcaaatact
    26041 tttcccttag gaatcaccat atcaatatcg ccttcagtat aattatcatg tatatatgaa
    26101 acttcattta ataacttacc atttatataa accttagaat ccttaatttt tagatggtca
    26161 ccaggaacac ctataaccct ttttacaagc tcttttttcc ttccattctc ttgtaataaa
    26221 tcagtcttaa atatcattat atctccacat tttggttctg ataacttata tgtcatcctg
    26281 tttgctacca aataatcatg tgatttaagt gttgggtaca ttgattctcc atttactaat
    26341 gttggtttta taaaacgagt tataataaat gcaaaaaaaa gtgcagtaat aattattttt
    26401 atccactcta caatctcttc tttaatagtt tcattcattc acaaattctc ctttatagtt
    26461 atattatctt tattgataat gtctcttaaa cactatcttt tagataagtc tactaaataa
    26521 ggtgttgtct tttttatata gacaactatt gtgtatggtc tggtgatttc agctaatcag
    26581 cgattgctcc aaattttata tgtttagtca atagttccta tcttagaaaa tggatacaat
    26641 ctgactagaa cctttcctaa aatggtatgc tcgtcgacca atccaacctc atcgtatcta
    26701 ctatctaaac ttttttctct attatctccc attgcaaata attttccttc tggaactacg
    26761 atatcaatat ctccatcagt acgattatta tgtatatagg aagtctcatc taacaactta
    26821 tcatttacat ataccttgga gtcttgtatt tttacatggt caccaggaac cccgataact
    26881 ctttttacta aatctttttt ctttccattt tcctctgtta agtcggtttt gaatactatt
    26941 atatctttgt attttggctc tcctaccttg tacgcaattc tgttaactat caaataatca
    27001 cgttcaacta atgtaggata cattgattct cctttgacta ttgttggcac tataaaacga
    27061 gttattgcaa atgccaaaac aagagctatg acaatcactt ttatccattc tacaacttct
    27121 tttttaactg cttcacccac taaaatcgtc tcctctgtgt taaatattaa gtcaatctac
    27181 agcaaaataa tctaccataa acctacaata taaatattat acttcttttt tctaatagtt
    27241 taaaatactt ttctaagacc tttaggataa tgattcttaa ttacaccaga agattctttt
    27301 ccccaaccta aaggtattcc ttcaaccgaa accaaaaccc atcctctact atcattagaa
    27361 tttacaacat ccccttttaa atatttaaga attgattcac tctgtacact gaagttttca
    27421 acatttttta catcttcaac ttttaagtaa tgagatagtg catgagaagg ctcaaatcta
    27481 ttcttcttta aaacccctaa atgcaaacca tatctcaata cttttagttt tttcgtatct
    27541 ggatatattt caggaagtag gtacaaattt tctcctctta aataaaattt atttttttta
    27601 ttactataaa aatcaacctt taaaaatttc ttttcaaact ccctataatc ctttatttct
    27661 ttatctaaat tttttatttt taattctttg acattacatt cttcttcttc taattttttt
    27721 attttggcaa caaaatgacc ttctcccttt atcttatgag gccataatct ttccatttca
    27781 ataagttctg catgtggata ttcactgata aactcattta taacatgctc attttcctcc
    27841 cttgaaaaag tacaagttga gtaaattaaa atgccatcct tctttaacat tttatatcca
    27901 tctcttataa tctctttttg gatggattga cattctacta cctttgcata actccaatct
    27961 gatatggcaa cctcatcctt cctaaacata ccttgcccag aacaaggtgc atctataata
    28021 accttatcaa aatacccatt aaacgtcttt cttaagctat tagaatcggt gtttgttata
    28081 atacaatttc tcgctccaaa tcgctctaaa ttttccccta gagccttaat tctactagca
    28141 ttaatttcat tagaaaccaa taaacctgta tcgtttagct tagatagtat atatgtagat
    28201 tttccaccag gagcagcaca catatcgaga actttttcac cctctttaat atctgccttt
    28261 ggtattacac tcattgcaga aggctcttgc aaatagtatg ctccagcctc atgcagtgga
    28321 tttctaccag gtctgtcaat tttatcatca taataaaaac cttcttctgc ccatggtatt
    28381 tgattcaaat caaacaactc caaatcaaat aattttttct tgtcaatttt taaagtattt
    28441 attctaagcc cagtagtctt actttcctca taacttttta taaaatcatc atattcatct
    28501 tttagtattt cttcaatatc ttctaaaaat tcctttggta attctgtcaa atctataatc
    28561 ccccttcaat ctgctttact tgtgtgtcat ttattatact ttaattattt atgtctttcc
    28621 tttaaatttt atttcttctt ctttttccta agattaccga aaaacacttt tttagagtga
    28681 ttcatatatt tctcaagttt atcaagattt atcttccaca aaattattac ataaactata
    28741 agtaatataa tagcccatct atattctatc atcaatatga aatcaaaaac tccatgtaat
    28801 aaaattggaa ttaacaccgc cataaacaaa tactcacgtc ttttattttt atttccctca
    28861 aatttatact tagaaatata gtagcccata gtaattgcaa acattacatg agctggtata
    28921 gagataactg ccctattaat accaacttgc agtgctagat ttctactttc agaaaaaata
    28981 taaaccatat tttcaattgt tgcaaatcct aaagctaaaa atacagagta aataatacca
    29041 tctaactttt cagtaaagtg tttttcttta attagggcag gaatcagtat cagagctttt
    29101 acaccttctt ctacaagtcc tgcaactaca aatgatacat atattagttc tgaataccct
    29161 tcaaatacat taaacttcat cagtaaattt tctaaaagta taattataac acttagaaaa
    29221 gcacctatta aaaaaaattt aattagatgg attaggggtt ctctacaata tctatcttta
    29281 gaccttatcc aaaacatccc tatcaatata ggaattattg ctaataaaaa taaatctagc
    29341 ttcatagatt attttccttt caaaattttt gatttattta tgatttatat catctactta
    29401 tttttaactt attcgtgttt taaatacata ctaaaatata cattaaatta ttttaaatta
    29461 tttaaataca aatatactca aatactcaaa aaaatttaaa tttatatcta tattatttaa
    29521 caaatttcaa gctatattca tatcttgaaa tataagggaa ctaaattcat ttaaagaaag
    29581 ggtgatttga tgcaagatgg tttcttaaca gtaagcataa ttgatgctac taacaataga
    29641 cctattcaaa atgcagtagt aaacatatat tcaatgtcta atggtagcca aagctcatca
    29701 actttatacc aaaacctaag aagtaatgaa tctggtcaag tgactggttt agtattacca
    29761 gcaccagatg tagattactc tctacaacca tctgatgtta gaccttatag ccagtatata
    29821 gtggaagcca tagcagatgg atatgagaca gttgtcatag aaggaacaca gttgttagct
    29881 acaattgaag caagacaagg agttcccatg tctcctagaa caagaagtaa gcgttctttc
    29941 tcaagacaaa gtgagttgat ttttgatata ggagaacata ctctatatgg tacttatcct
    30001 cctaagattc cagaaagtaa cttaaaacca ttaccacctc ctactggttt cgttgtatta
    30061 gataaccccg tagtgcctga atttatagta gttcatgatg gtttgccaga agattcatca
    30121 gctccaaact attggattcc atttaaagag tacattaaaa acatagcgtc atctgaaata
    30181 tattcaactt ggcctgaaca gacaatctat gcaaatgtaa tagctataat atcatttact
    30241 ttaaatagag tctttactga atggtataga aataaaggat ataactttac aataacttca
    30301 acaacagcat acgaccataa gtttataaat aatagaaact tatttgaacc aattaacgta
    30361 gttgtagatg ctatttttaa tacttttata aaaagacctc ctacatcaag acagccacta
    30421 ttagcacaat attgtgatgg acaaaaatcc caatgtcctg accaaatgac tcaatggggc
    30481 agtaaagact taggtgacca aggatatgac tatgagagta tactaagata tttctatgga
    30541 gatgagatag tatttgaaag agcacctata gtaagtggtg taccagtgtc attccctggt
    30601 actacactac aagttggttc ttctgggcag tatgttagaa ccatacaaaa tcagttaaat
    30661 gctatatcta attcttatcc agctgtacca aaagttatag aagatggtat ctatggaaca
    30721 gatacagaaa acgctgttaa gatattccaa ggaatctttg gtttacctca aagcggagta
    30781 gtagatttta aaacatggta tgaaatatcc agagtttatg tagctacaac tagaatagct
    30841 tctttaaatc ctttaattta aagcttgatt tagaacataa actcaaatta ttgaataaaa
    30901 ttattaattt aaaataaaag tggctgttat gaactaatat ataccataag tattacttat
    30961 aagtattgta gtcttaacag ccatttttta gttataactt gtttttttag aatcttaaaa
    31021 ctttaaatgg gggattttaa gcttcttaaa aacagtgctt agcaacttag atttctttaa
    31081 aatattatat ttatttttaa gtttaataaa atgctattct aacgaaaaac ctacttttta
    31141 tttaaaatct cacttattat ttaaaacact atccatcact tagaatatta cttcttatat
    31201 aaattattat ttattataaa tacaaataat attaatttaa aaagttattc ctaatttaaa
    31261 taatactact atcttcatca gtgaacctaa actgcaactt tagacttatt agctaaagcc
    31321 aatattagac ctaaagctat agatgcaaat gcagaagcaa ttactctata ctcagcaggg
    31381 aataaaaata caattgtatg acatggtatc cagaaaaatg gtatagtttt taaaacacta
    31441 aaaccaaggt aagcattcca gtccacaata tttaccacat ctttaagttt taccttaatc
    31501 ccctttccaa cctcatattt tttatctata aaacagtcca taaccttatg gaataaaaat
    31561 acagttggtg acattagtat attcatagtt gcactcttaa atagagcatt tgcaaaagct
    31621 attccctcaa atggaagcat accatccact tgtgcttgac ctacacctga tgagtagatt
    31681 gacattccat atgtggtaac tacacctatt attccccaaa ctattgctct ataaaatact
    31741 cctactggta ttttccaatc cttatacaaa attctaacac caagtaaatc tcccattgta
    31801 gctaatacag caaactttaa aaaacctcca atatatggat gtgcacctgt tgcttccata
    31861 aatacttctc tactacttgg tattgctaag acagcaataa tacaaataag aactccactc
    31921 catataaaat cgcctttttt catatttata aatactattt aatatataaa tagttctcct
    31981 ttctattaaa gatttattta atttacaatc tatctacaat tatttattaa tcacttatta
    32041 ttagatattc attttccata tttaaattta ttctatccct ttatctattt attttcttac
    32101 tactctatcc accattatct atatatttat tttacgatta ctctttcacc ctaacccttt
    32161 aactatctat tttttcttac tattcttatc cacatcatcc atatatttat tttacgatta
    32221 ctctttcact ctaacccttt aactatctat tttttctgat attcttatcc accatcatcc
    32281 atatatttat tttacgatta ctctttcacc ctaacccttt aactatctat ttttttctgg
    32341 tattcttatc tactattatc tgtatattta ttttatgatt actcttttaa cctaccccct
    32401 atactttata gtaatatgtt tttaaccttt ttcattattc ccaatatgct ttataactac
    32461 aaatactctc cccccttaaa aataataata aaattaatca ataaatttat aatcatatta
    32521 ttactctatg tattaagcaa ttactatgcc aataaacttt gattttttta aacaaatctt
    32581 aaaaatccta aaatgctaat tttctttaac ttttaatgaa tctaatagat aacatttaat
    32641 tttcgttata tttttcagaa tatttctatt attattttta agaaaaaaaa ataatgttaa
    32701 catttcttaa catacattaa aaaatgttaa cattataaat tgggtttaat acttttactt
    32761 tgactcgatt tacttttatt ctacttctta ctttattttt aacttagact ttattttttt
    32821 attacttatt tgagtcttat ttattttatt ctcactccat atgttcaatt acatttgtct
    32881 aaattctttg atacttttat tacataattt taacaagctt aagtgttatt tgggtagtgc
    32941 agttgataat tatttaaata atcatcaact gcatgtttat atcattacag tagcttaatg
    33001 tatttaatca tacttactta ggattttgaa atatcttaga gattatattt aacattagtc
    33061 aattgctgca taattgtaag caattgaaat ttgagaccca tcttcatttt ctatagtgat
    33121 aggcttcata atttttaatc cttcagtttt tatcttttct aattcttgtt ccattttctt
    33181 aattgtttcc tcaaggtctt tttgacttac atctttgact gcattagggt ctttagcata
    33241 gtcttttaat tcttgaatat gtttagcata ctcttcataa gtataatgct caacaccata
    33301 cttttccaat tcagtagggt cagttattcc tgattttatt agagattcaa atttaggtaa
    33361 agcaatatta gatgaatcat ttccatttgc aaatactgct ccagttcctc ctagtaccat
    33421 tgcagatacc atcattgcac ttataaggga tttttttatt ttcataacca atcttccttt
    33481 cttagagatt tatttgggta gtgtagttta aaatgactat tgcaatagtt atcaactaca
    33541 ctcttagact atcacagtag tcatgtttat gtcaagcctt tttaaaaaac ttttcaataa
    33601 aaaatactat ctcaaagcaa aattaattat tttgagatag tattttaatt ctaaatcttt
    33661 tatattacta agatttatgg ttattctatc catgttctat attgttcttt attaactgct
    33721 aacaaattcc cttttcttaa tatgacaaag cgattatcat tatagccact tcgctcaatt
    33781 gaaacttctc ctgaatcagt ataaagtaca tccttactat tactagattt atttacatac
    33841 gtttcttcac tattctcaga attagttact ttgctcatag atgattcttc atgctctcta
    33901 aattcaatta cagatacttt tgccgtacta aaatgagtct ctccatcact tttagcttta
    33961 ctaacaagaa tatcagattc tactttggga gaatataaat cagttgattt actacttatt
    34021 gaaaatccaa ttttatcact ttgttcattt tttgttaaac caaaagattc aacctcatta
    34081 atctctttat tttctgttgc aaaaacaaga cctgtcccac aaactaatac agttgaaact
    34141 aaaaaagtaa cataagttga ttttttaaat ttcataatat taactattct cttttctatt
    34201 tttgtctttc caaatccact acatattgtc attgaaaatg gattattctc ctctgctaga
    34261 cttattagtg tggttgcata atcagcccta tattcttcac caagtatact cataaccttt
    34321 tcatcacaac taaattctat gtctttattt agtaaaaaaa acatcaccca aactaaggga
    34381 ttaaaccaat ggacaacaag agctacaagc ataaataact ttaacagatt atcaaagcta
    34441 ttaatatgaa ccatttcatg agttaaaaca aagtctaaag tttgattatt agcataattc
    34501 atttgctttg gcaaaataat tcgtggtttt aaaataccag atgtaagtgg tgtcctagta
    34561 aattcagata tgcaaacaat aaatcttcta aaacggctat tcttacacat ccatttttta
    34621 atgaactcat gattttttat atgaattgaa gttttaaaaa gattaattat tttaaaatat
    34681 ctaaagcata aaagtatgct aaacataata gtaactataa aagacaaaat gcccaacatt
    34741 tccaacatca taatattttc aatattagac attatttcaa attcgtcaga attgttttta
    34801 cctgtagagt cactagcttt cttaagagta taattttctg ttgatgtatt acccaattcc
    34861 acatcaaaag tcgattcaat tatactataa atactaaaac cagaatttaa acttactggt
    34921 attagaagtt taaataaaac aatcaaccac aataatacaa ataccttttt aggtaatttt
    34981 ttaaataaac atgctcttat aaaaataact attaaaagta atactccaga agtaaaactc
    35041 atttctaaca atttaatgaa cataaatctt acctcacttt aatttttcaa caatttgttt
    35101 aagttttgta atctcatcac ttgaaagatt ttctttatta ataaaagctg aaagaaattt
    35161 ttctgaagac cctccaaaca ttttattaat taaagtttct gtttcctgtt tttgtacttc
    35221 ctctttgctt attaaagctt tacaaacaaa attcggctca attctctcta ttgcaccttt
    35281 tgacactaat ttttttataa cggtatacgt agtgtttcta ttccatcctg tttcttcttt
    35341 taaaattttt actaactctc cagccttgct ttctcctctc tcccatagaa cttccattac
    35401 tttaagttct gaatcaaata attttatctc catataaaat cgctcctcaa atatagttat
    35461 cacaatagtc attactataa taaaaaacta tcatagtagt ctatactatg tcaatcattt
    35521 attttttaat aataaaaact gtctttttaa aaaattctta taaaagacag ttttatcaat
    35581 gttatacttt aatgtttaat taaagccata ttttatttaa atatataact atctatctta
    35641 gtacatagta taagattttt ctttatctaa tagtatatcc tctacatctg ggttttcttt
    35701 tactaattgt ctataaaaat tacaattagt aacacccaca tatggaatta gccatagtag
    35761 acctattcca agagtagcta ttgaaagtat ataccatcct ataaagctaa agtttagtac
    35821 aaataattta agtacatttc ctttcatcat atctaaacta gcacccattg atttaaatac
    35881 acccatatta tccttgtctt cacaaattaa gaaagtagct tgagaaacat ataatagcaa
    35941 tatataaact ggtaacataa gaacaagtat tataagaact agagttattc cagtagaaat
    36001 aatagtccct attccaacat tatcacttga taaatattca attgctccac tagtaagtaa
    36061 aactccaaat gataaaaacg ctcctataat tgtgattata aaagaataaa tatacacaat
    36121 aattgattca aataaataaa aaccaaaact tcttaaataa attctcccac ttacaaagat
    36181 atctcctatc ttgacttttt catctttagt aattttcaag aacatacatg taaatcctgc
    36241 tgaaacgcaa aaagctatta cagccactac aatagtagtc aatggttcaa aaggtaatcc
    36301 tacaattgat attaatacta tcaatgcaat atatactgcc atagaaattg cacatatccc
    36361 ccagtttcca gataactgag ctttagatac tcgttttaat tcttgccttg ataccataaa
    36421 aaacacccct ttcattttat aaaaaaactt ttaaaaatat aaataatctt ttaacgtata
    36481 atattaatat atcatatttt cgactatata agatacaatt attcaccatg ttttatcaag
    36541 atatgccata attgtattac tagttttata tagtcaacat taccaaatac atcaaataaa
    36601 tttgattaat tattcaacaa gtaataaaat aatttctatt aattatactt tatttagtaa
    36661 acaaattatt taataaaaaa attacctaat acagtaaatt aattggtaag ataaattatt
    36721 tattattagt aaagtaaatt atttactatt tatcaagata aattatttat aaaataaatc
    36781 atttataaaa tataatttat actttgaaaa taaaataaac tatcttccaa acattttatt
    36841 atatgcttaa aagatagttt tgtgtcttta aaataaatta aattgtatat attccttcac
    36901 ataacttttg tatattacta ggtggttgcc atttaccatc ttttttagta tatgtaatca
    36961 tagttgtaac ttccttagtt ggtttcttat tgtaaaggtc tataatcatt tttgtcatat
    37021 catcttgaac ttctttttct tttttatcgt aattcttttc atcagttaca taagatttta
    37081 ctaaagtgtt cgcttcactc attactttac tagtatctaa agctttactt acaactttca
    37141 aagttatctt atccttacta gaagattcca ctgttactgt cttttcaaca ccttgaatta
    37201 atttaacaat tgtttcgtat atcttttcag cattttcttt accataaaga ggtgtcaatt
    37261 gagcaatcat tgaaaccttg tccttgctgt tataagtttg aatctgttta tattcagctt
    37321 ctgttaatgc atcagaaatt cctttttcat catacttata catttctaat gcagctaaat
    37381 tagcttcaaa attcgacttt actttttctt ctgcattaga acaccctata gttagaacta
    37441 aaactagagc cataatcgta gataatatta acttttttac cattttcata caaacatcct
    37501 ccctcaatta aaataataaa aaatttattt atcaacatta taacataaat ttgtctaact
    37561 atagaattat tttgaatatt ttaccacttc cagtctattc caataccgtt ttcttttgct
    37621 ttatcgtata ttctttttgc tgttacgaca tcttgtacac ctatcccaac agttttaaat
    37681 acaattatct catcatcatc ttctcttcca ggaatagttc cgtttataac atttcctaaa
    37741 tcaccactaa aatcatcttt acttatctta ccttctttta atggaattaa tatatctcct
    37801 gactcagata aaactgcatc tgttgattca aaaaatatct tagacgctct agttaaacag
    37861 tttgggcaca actcttgcat atctggcata tatgaaccta ctgcacttat taaagctcct
    37921 tttttcacta agtttccatt aagtactggt tgttttgatg gagtagctaa aactatcaca
    37981 tctgcgttat ctatggcttc gtcagatgat tcaactgcaa ctattttagt attatattta
    38041 cttaatttta agttcatttc ttctgcaaat ttttctctac tttccttgtt tctactaaaa
    38101 actcttacct catccaaatt tctagcttct atcatggctt caagttgtgg ctcaccttgt
    38161 cctcctagac ctatcaaagc tccaatctta gaatcttttt tagccaatac gtctatagct
    38221 gctccagagg ctgctccagt acgaatctga gttacataag taccatccaa tactgcacta
    38281 acttctccag tttctccatc taataatagt actgttgctg gaattactgg tttgcctttt
    38341 tgagcatttt taggaaatac agatacaatt tttattcccc cacagcctaa ttcttctacg
    38401 tatcctggca taaataacat actagcatct tgacttggaa cagatatatt ggttctcaaa
    38461 ggatttacac tctttccttc acaataaatt ctaaaagctt ccttatcagc ttcaattgca
    38521 tctctcattg taaatacttt ttttatgtcg tcttttttta aaagtagcat ttttataccc
    38581 ccaattttaa taagtctcta tgctaaatat tatagcataa catttaattt aatcttctat
    38641 ttcaaatcaa ataaatctac atactctggt tttagcatag aacttatcaa cgctttattt
    38701 attgaaaatt ctggtattcc tgctgcatat ggagttatat catacaaatc aaaatataca
    38761 actagattct catcttgcaa gtaaaagttt tgattctctt ttataccttt aaaattatat
    38821 attccgatat tttcttcatc ctttttttca agttcagcta tttgtctttt aatttcttca
    38881 tctataactt ctttatattt agtattatcc ttaaacaagt ccattaattc taaaaatttt
    38941 ccagttctca tatccacatt atatgctata tcttgataaa atccatgtgc tccaccacta
    39001 taagtataat atctcacttt tatactaaga gcagaatcag tattcttttt aagttcaaag
    39061 tctacatttg caacaaactt atttttctcg tcaggattat ccttaagata ctgctttgct
    39121 tctttatatg atttattata aaattcaaat atgtcatttt ttatcttatc atttgtagac
    39181 ctttcaacaa ttttatttga atttgttatt acaggcatgt ttatagtact ttctaaatac
    39241 tcatcatttt tcactattgt tttacttcct attgtactta ctgataaagt ttgtttacta
    39301 tttgtattac cctttggtaa tgactggtta ctcataacag tcactgcttc cttattacta
    39361 tttaaattaa ttgaagcatc tttccttaaa ttattatatt tatagtcatg tttaattgcc
    39421 aaaacagcca ttatagtcaa tgttaaaaca aatacatatc ttaaaacttt agcttttgta
    39481 tcgactttaa aaaatttcat attatcattt tcctcctaaa tataaatctc tcttattata
    39541 tttggagttt ctagggtttt ttatccatat aatttaataa aagattaatt tttatttata
    39601 aaaaattaat ctttttgttt taaaatatta atatgtctta tcaaacagtt tgaaatttca
    39661 ccaagaggta attgtaacat aacagaacct ctatcaaaag ctaccattgg cattccatat
    39721 actatacaag aattttcatc ctgtccaatt gtaaatgaac cattttcttt catttttaaa
    39781 agtccacttg ctccatcata acccatacct gtaagtatta ttcctattga atttttacct
    39841 gctacttctg ctactgaatc aaacaaaacg tctactgatg gacagtgacc acttattctt
    39901 tctccttttt cacaagttac ataatatcct tgtttatccg tacacaattt catctggtaa
    39961 cccccaggtg caattaacac atttccttgt tctactctat cattattctt agcttctctt
    40021 acattcataa tacactgctt gtcaagccgt tgtgcataca tataagtaaa tatagctggc
    40081 atatgttgaa ctacaacaat ccctggtgtt gattttggta ggtcttttat aatttcaagt
    40141 attgcctctg taccacctac agatgcgcct atagcaataa ccatattatt aaaacgttcc
    40201 acattaccgc ctccaaaaaa tcatatatca aaaatacctt tttatcgttt atatatagca
    40261 ggttttacat atttgtattt agtactactt ctgttgatta cttctgcatg tcctacaaac
    40321 aaaaaactat cttttttggt agcattataa aatttattta taagttcttc tcttgttttt
    40381 aaatcaaaat aaatcataac atttctacaa aaaatcaaat caaaatgttg atatgagaaa
    40441 tcattcatta aattaaacgg cttaaaaatt acactttttc taatcttatc acaaatttta
    40501 aatgtaccat ccttgttgtc tataaaatac ttcttcttcc ataactcagg aacattgtta
    40561 acatttgatt ctatgtatat acctctttta gctttttcaa gtgagttagt tgaaatatct
    40621 gtggctatga ttttaatgtt ccacaactct ttattatatc caaaataatc atccaaagtc
    40681 atagctattg aatacgcttc ttctccacta gaacatcctg cactccatat atttatgttt
    40741 cttattttat tattttcttc ccaaaaagga agtatactat tctgtataaa ctcaaaatgt
    40801 tgaggttctc tcataaaaaa tgtgtggtta gtactcaatc tatttattag gtttatagct
    40861 tcatttcctg tcctatcttt aaataataga ttcatatatt gactaaaaga actaagtttt
    40921 ttctctatca ttgtattgta taagcgacct tcaattaacg ctcttttttt acttaaatca
    40981 ataccatatt ctttttttac atggtttaca agaactataa attcttcatc tgtgagtttt
    41041 atcatgcaaa aacttcctcc tgctaattta tcagaactaa ctatatgcta ttaatcaaaa
    41101 actttcgaat atctaaaatt aatatagaat tatcttcaac tttcgcaatc tcttttatat
    41161 ctttattaat attagtgttg ttagaattag tcgtctctag taaatttaga ttttctatat
    41221 gaataacatc aacaacttta tctacaataa ttccaacttg atactcatca acctttgtaa
    41281 ttattataca agttctctca ttataatcag ctttaggaag attgtacttt atatgcatat
    41341 taataactgg tattattctt cctctcaaat taataactcc acttatatat gttggaagac
    41401 atggtacata cgttattgat tgaaatctta tggtttcaat cacattttct aattctattc
    41461 cataaataac atcattgaca taaaatgtta atacttgttt aataatttca tctttagcca
    41521 tactttaaat cccctaatat atttctataa tgctatctgc atctataatt aaacttatac
    41581 ttccatcccc aagtattgta catcccgata aacccttatt ttttatatta aatcggttaa
    41641 aataaactgg aaatggtttc acaacaactt gctgattacc tattatttca tcaacaaaaa
    41701 tgcatactgc tttatgctca ttttcaataa ttatcatatt accattcatc agattggtta
    41761 cttttgtttg aatattatat attttatgta accttataat gggaatacat gctccatata
    41821 ttgtaattaa ctctgtctta tttccttctg taattatttg atttaagtct gtaagtttaa
    41881 atgttcttct tatggatgat attggtaaag taaatagtga atctccaact ttaaacttca
    41941 taccctctac tatagaaaga gttaatggta tttttatagt aaaggttgtc ccctcatcct
    42001 gtttactttt tacttcaatt gaacctccaa ctttttcaat acttttacga acaatgtcca
    42061 tgcctactcc tcttccagaa aattcagtta tagattcttt tgtagaaaag cctggagtca
    42121 taatcaaaga attgacctcg tcatcagtat actcattact ttgatgttta agaagacctt
    42181 gttccttagc ttttgccaaa atcttatctc tcataatgcc tctaccatca tctgaaatac
    42241 ttatcacagc ttctccgcct agattttcag cagataaaac tatctttccc acttcttctt
    42301 tacctttcgc tatacgctcc tcaataggct ctattgcatg gtccatagca tttcttataa
    42361 ggtgcataaa aggttccgct aaattatcaa ttacactctt atccacctct gtttctgctc
    42421 ctatagttat taactctaca tttttatcta attttttatt catatctcgt acaattctat
    42481 gcattttttg aaatacacca gcaatttgaa tcatacgcat agacattact atatcttgca
    42541 attcatctgt aagcttgtgt aattgtcttg ttgccttatt gaaattatct atatcaacac
    42601 ctgtagaatt tacgctattt acaaccattg attccataat tacaatttct ccaactatat
    42661 tttgaagtaa gtccaatttt tctaaattta cactcataat actctgctta cttattggta
    42721 aatgttcatt ttcttcactt agactatctt tttccatatc agttttttca tttaaaacat
    42781 cttcttgtat ctcatcttct gtatagttat tttgataact tttacttact ttattattat
    42841 cttttaattt attttctact gcatcattgt ttgatgtact tttcatttct atttcttttt
    42901 tactaatatt tatgtattct tttacataga gattatcttc tatagtttta taaactattg
    42961 ccttatcctc tttagctaca aattgtatat aaaacccata acttttaata tactctgtag
    43021 actctgcatt tgtttctaca tcttttggat aaaaatctat aaattcacag taatctctaa
    43081 gttcaaatac aagcatgaaa gctctcacat tttccatcat gcaaccttgt tcaaagatta
    43141 tttttactac atcagagtct tctttgtatt caaaatttga atcgattact tctttttcgt
    43201 ctttactttc taaatttgca ttatcctttg atttcataga acttgataat tccaaagtac
    43261 tcacatactc ttcaattcct tcaataaaat tagagtaatc agaagatata caacctcttg
    43321 attgtaactc atctatatct cttcttataa aatctaatga ttgaaagact aaatcaaata
    43381 ataggtcatt gtctaaaact tctattttac cttcacgtat agcataaaac aagtcttcta
    43441 cactatgtgc taaagcagat atattgtcta accccatcat agatgctgaa ccttttatcg
    43501 tatgcattat tctaaaagtt tcattaatgt tgttatgagt aaatactttc tctttttcta
    43561 tttgaatcat aatttcatct aattgttcga gtaataaact tgtctcaaat ataaacatat
    43621 ctaacatttg tctcatactc ggttcaatat aattcacatt tatcacctac gacctacaaa
    43681 taattttcta ttatatatgc atctcataat ttaaatcctt gatgattctc ttatctcact
    43741 atatgtacct cataatttaa atacacaatt attctcttac ttcaatatat atacatctca
    43801 taatttaaat ccttgataat tctcttattt caatatatat acatctcata atttaaatac
    43861 atgataattc tcttacttca atattcacct cataatttaa acccatgatg attctcttac
    43921 ttcactttcc tttagatgaa atttttctac taattctttt aaaatttgag cctgagcaga
    43981 catctcttct gaggctgctg cactttcctc tgctgttgct gagttcattt ggactactat
    44041 ggaaatttgc tctattccag ataaaatctg tgtaattgct acttcttgac tatgtacagc
    44101 cgaagaaata ccattaatat aattagtagt tttttctaca ccatttacta ccaagtccaa
    44161 tgcatttgca gtctctttag caattctgac accattttct actgttttaa tagcttcttc
    44221 tatgagaata gctgtatttt gagctgcttt tgcactttta ccagccaaag acctaacttc
    44281 atctgctaca actgcaaatc ctctaccata ttgacctgct cttgctgctt caacagctgc
    44341 atttaatgca agaatattag tttggaatgc tatctcatct attgttttga ttatttttga
    44401 tatttcactc gatttttcac ttatttcacc cattgatgtc atcatatcat ccatacatct
    44461 acttccaaaa ccaacttgtg atgcagattg gtcagatacc tcacatgcaa gactagcact
    44521 atctgcacac ttcttaattc catctgatat ctcattaatc gtggaagcta attcttctac
    44581 tgaactagct tgttcagtag caccctgtga aagagcttgt gcacctgctg caacttgttc
    44641 tgaagcactt gcaacttgct ctgctgataa atttatttca gaaaaatcac cattaaaaga
    44701 gtttattata ctttctaaag atattttaat tgatttaaaa tcacctataa attcttggtc
    44761 tatctctact cttaaatctc cttttgcaat actagttaat gtactgtcta taaggtctat
    44821 gtaatttaaa agcatacttt gcatcttttt gacagaactc actaatagcc ctatttcaga
    44881 tttactttct tcaacgtcta tacttgttct taagtcccca gatgcaattc ttgaaaagtg
    44941 tttttctact ttattaatag gaatcactat ttttaatttt attactgtat attctattat
    45001 tgtcaatatt attaaaaggg aaagtataaa tattgttctt aatattagac tttgtaattc
    45061 tttttttact tctacaattt tggaatttga acgggtaact atatcctctt gaaattcatt
    45121 tattaaagaa tccattttct cttgggagtt tatatagtca ctaccaaaaa ttatactttg
    45181 agctttactc ttatcattac tttcgactgc ctttattgca ctttgttctg ttggtactaa
    45241 agaatctgat atttcttttg cttctaagat tttatttgac tcgctctttg taagaccaat
    45301 tttttctaat ttgtttaaag ctgattctct tgtttttccg tataattctt tttcataaat
    45361 atctttattc tttttttctc ctgtaaatac atatcttctt aatacatcac ttatctctct
    45421 agttgtatct tttatatact gactttgagt cctcaaatta ttcatatcat taatactttt
    45481 ttctactttt tcaaatgctt tataagatga aatagaagaa aaaatccctg ctagaacagc
    45541 caatactata ataatcagca atacaattgc taatttagaa agctttactt ctcttttcat
    45601 atctgtactc cttcataaag taagtttata tcttttttaa tcctttcatt gtactcacta
    45661 cgctacaatc ttttcctaag tttttaccct catacattgc tttatctgct aaggatatgt
    45721 tttcttctaa tgatatattt gagtttactt ctactactcc taatgtaata gtgcacttta
    45781 ttttatgttc tttatagttg aaatcaaact cctttatctc tttacggatt ctttctgaaa
    45841 gtatcttagc accttctatt ggagtatttg tgagcattat caaaaactct tctccacccc
    45901 atcttgatac agtatcaatt tgtctacaat tcttttttat tatacttgat attactgtta
    45961 acacgaaatc ccctgcttca tgcccataag tatcattgat aaccttaaag tcatcaatat
    46021 caccaaggat aagggatatt gatgtttcac tatatttatt aattcttctt tgctccataa
    46081 gctgattaat tatatgtcgc ctattgtaaa gacctgtaag ataatctctt acaacgagtc
    46141 tattcaattt ttcaagagaa gattccagtt cattatttat cttttttaat ttatcttgag
    46201 atttctttac ttcaagatga gctataacac gagcttttaa ttctgtcata ctaaaaggtt
    46261 tcaccatata gtcaattgct cctacaccaa atccttttac tatgtctgta tctgtatttt
    46321 ttgaagttat aaaaattata ggtatatctg ctgtacgagc attagatttt acttccttac
    46381 aaaactcaaa accagagtta tctggtaaaa ttatatcaag caaaataatg tctggtataa
    46441 attcttcaat aaattctttt gcctctattg cattaaatgc ttttttaacc ttaaaattat
    46501 cttttgtaag tgttttatct attaagtcac acatcagaac actatcatca acgactaaaa
    46561 ttgttccctg ttgcttattt ttcatataca aacctctctt aaacataata tattcaaatt
    46621 ttaatgattt aaaattttta tacttaataa ttataccact atattcttaa atgttctcat
    46681 cacaatcttt ttataataac actccaacta catccctatg ttacatgata gtgcaatcaa
    46741 acccattgat taattcatct attaaaactt catctttatc tgtcaaaagt ttctccaaat
    46801 ctagtaaagt aattatttta ccttctaatt ctccaactcc acttacaaaa taatccgaat
    46861 attctatagt aactcttggt ggaggtgata ttttactttt ttctaagctt actatatcat
    46921 caactctatc aaccacaaat ccaactacca agtcctttat ttcagttact actatataca
    46981 tgcaatttgt agtcattaat tcatcttttt taagtctcaa acgcatatct attatcggaa
    47041 tgatttttcc tcttagattt attatgcctt tagaatatgt aggtagttct ggaataaata
    47101 taatttcttg atttccagta atttctatta ccttttcaag ttcaacccca aaatcttgct
    47161 catctacttt aaactttaga tacttaattc cttcatcaat tagtccataa tctaaatatg
    47221 ggtcatctgg aaatctcatt taatacctcc ctcctaaaat acactttcta tgaaatatat
    47281 attataattt cttcttacct ttatttattg aatctacaag taattcaccc gtctcagtgt
    47341 aaaaacgtat tgttctacca taattcatac ctgtgtcctc agctaatatt ggaatattta
    47401 atcctaaaag agtttttttt actgcctcaa cattcctatg tcctatactt gcaattactg
    47461 aattgctact tcctaaaaac atctgagcac ctccagcaat ttttgctttt atatatattc
    47521 tatttgcacc tatattctcc atagatttaa tgagctcatt tattcctgtg tcagcaaatt
    47581 tacacttatt ttcaatgtta atagcatctt tactatatgg caacataacg tgtaacattc
    47641 caccaattcc agctacttta tctatcaaac atactcctac acaagaacca agtgcataag
    47701 taactaaaac atttggtcta taggctatct tcatatctgc aatgttcact actatctctc
    47761 tattcatact tctaatccca acctcacgag tatttctcta agtgagctca tttctggaat
    47821 catcaaaatg tgactagtaa aataattatc actcatttta aatttatttt ctataaataa
    47881 gactttgtca ccaacatctg aaaatcttat cataggtaca tttagaacag ctccaaccat
    47941 atcaatacat atatctggaa ttgaaacact tatagtcatg tttaacatag atgcaatagc
    48001 atttacatat gaacttgcca taatatttcc tatttcctta attgctgaaa tttcaattgc
    48061 ctcaatctca tctaaaaaag cttcttcttt attaaaaaga gaacttagca taagttgagt
    48121 tattgattca tccaacaaaa acataaacat tccattgata tcacctttca tatcgagtaa
    48181 aatacatact actttgtttt ctggaccacc aagcaaattt gtcgcttcat tatattcaag
    48241 tatcttgacc ataggtatta atacttctac attgctattt atcatggatg caagtgcagt
    48301 aattgcattc ccagagccta tattaccaat ttctctaaga gcatctatat gaacatcatc
    48361 aagttctaaa taatttataa tataaacccc tccctttatt attgcattta tttgcttttc
    48421 attgtattag tgtatattta cacttttatt ttaaagcatt atctacaact ttaactaatg
    48481 tttctgtttt gaagggcttc actataaaat ctaacgctcc aagttttatg gcttctacaa
    48541 tcatattctc ttgtcctatt gcagagcaca ttacaacctt agcacttgaa tccaactttt
    48601 ttatttctct tagcacctct aaaccatctt tttttggcat tgtaatatca agcaacatca
    48661 aatcaggctt ttcatattta aatatattac acgcttcttc tccatcattt gcttctatta
    48721 aattattata gccactttta ctcagagctt ctttaattat cattctcata aaaatagcat
    48781 catctactat caaaatttta ttttccataa aactaactcc tccatatgta caacaataaa
    48841 cgcttttatc ttcagttatt gtctatacta tctgactatt tttcgctaca caataaatac
    48901 atttcattga taaataaaag taattattta tgccatatta tacttaattc tcttaacata
    48961 atttgtcaac aaaaaaactt atatatctat tgtaatatat gtttggcgtt ttgacgagtt
    49021 attaaaaata taattgtata aaacataaaa agttatcaaa agtaattaaa ttataataaa
    49081 acaactttat acctttttta tgtttgtata aaaaaaattt tcagattcat taaaatcatt
    49141 tctgtagatt catataggat ttgactttct caatatctaa tagatagttg tttatttact
    49201 taattatatt tctctatatg tattatcgat taaattagat ttagctttat acattatttt
    49261 ttatattttt caaattgtat actcataaat ccagaagtat tctaatgtgt ttataatact
    49321 ttttttcata ttttaaatta aataacaaat cattatattt acaagtatca tttatcaata
    49381 aacaatatta aatgaagaat atgtctgaag attcaaagtg atactgatac tattaattac
    49441 taaaaaagca gtaaatcttt tacagattta ctgcttatag ttataaataa taaaactatc
    49501 tataataaat gtactatact caatatttca ttcaatatag taataacaaa tctactttat
    49561 tcctatgtaa atatgaattt cttgtttctt tgtatcaaaa gtattacatt gatactcttc
    49621 aaaatcactt atataagtcc tatcaaaatc catttgccaa aactcaaacc aaaaatctcc
    49681 tacttctttt tgacctccta ctataacaaa ctttgcatac ttacctgctg gtataacttt
    49741 actaataata ctttctccaa cagtattatt agtgtttaat tcttctaaat tcttctcttt
    49801 atcagaatta ctatttactt cacaacatgc aacaaagcta tacggacttg taaaatcacc
    49861 ctggtaatct gtatatagac ctattgtctt gtcattcttt ttacccttta tagcattata
    49921 tatccctttg cccataaatt ttttccacaa ttcacctata tcatttaccg cttgtccatc
    49981 tttatttgta gtctccttcg atattcctat aactattttc tcatttatct ctactatttc
    50041 ataattcata ctttatacct cactttgttt ttattaatct attttatttt gaactaattc
    50101 aattataatt tataatatac gacaccttta tgtcatattt ttaatataat taaactcagt
    50161 gagatattat atactaaatg caagatatta tatatttaat aaaatcttta atctagcatt
    50221 atattataat gaataaattt tagacaactc ccttagtcta gttattacat tatccctaac
    50281 atctttaggt tcaagtactt caacattgtc accaaatgat aaaatatatc cataaatcca
    50341 ttcaccaata ggaaattctg taattacatc atatgtatca tcttcatttt tagttattaa
    50401 atccttatta aaatcatcaa atactctaaa aagcatcttt tctttaaacc tcaatttcaa
    50461 cgttatagta ttttccttaa ttactttaga atcattcaaa catacttctt ctattatctt
    50521 tcttgaaaat acttcatcct ttatagataa attccttatc ctactaattc taaatatcct
    50581 aaaatcatct tttagtttac aaaatccata caagtaccaa gtcttactct tatacataag
    50641 cttcagtggt tcgacagttc tgtttgtctg gcttgacaaa ctatttacat aattaaaatt
    50701 tatagtatta cgccttaaaa tagcttcttt tatttttgta aatttatcat cttcattaaa
    50761 attacttccc cattcagtaa agtctatttc aatccagttt gaaaaattct gctctccaaa
    50821 tattgagcca attttattta ctactgaatt tatttctgga tacttagtcg cctgtaatgt
    50881 tttcagtgca actattaaac tctctttatc tttttttgac aatatagcct tgtctataga
    50941 atattcttct attaaagata tccctcctcc tttgcctttc gtcatatata ctggtactcc
    51001 cgacatagac agagtttcta tatctctata tatggttctt gtagaaactt caaatctatc
    51061 tgccaactct ttagctgtta ctaatttttt atttaataga attactatta tttctgttaa
    51121 tctatttatt ttcattcatt accacctact aaaattatta aatttattta atctaaatta
    51181 atcatactaa tttttaaata aataaaatct tagaatctta tctaaattat ttttacatga
    51241 ttttatttac tttctattat ctttctcact ttggatatta tcatcttaat ttatttatta
    51301 ctatatcaat ttacttatta tcatctcatt tgttatcgtc ttacttaatt tacttatttc
    51361 tatatcaatt cacttattat tacctcactt gttatcatct tacttaattt acttatttct
    51421 atatcaattt acttattatc atctcatttg ttatcgtctt acttaattta cttattgcta
    51481 tgtcaattca tttattatta tctcacttgt tatcgtctta cttaatttac ttatttctat
    51541 atcaattcac ttattatcat cttaattcat ttgcttatta tcatttactt tattcaattt
    51601 ctatatcaaa attagtattt gtacttaata cttaaaatta atttaaagtc tttacatatt
    51661 atttattttc tattgtaata ttcatttcca tactttacta agctacttcc actcatttat
    51721 tttaaaattt caatttacta tttctcaact ctatattatt atttttcaat tttatattac
    51781 taattttaaa gctttttagc tattattcct acaatattta aacaattttt tcataataaa
    51841 gctatattac aatatattca aaatatgtaa tattttagat atttttcgtt gacaatgtta
    51901 aatttttgtt ttatccttaa ttaaggacat gttattgaca tttctgaaac ttatttgaaa
    51961 tagttttttc attttattta ggaaaacgta ttatacttaa gaaaacgtat tttctcattt
    52021 cagataagta aaatatttat tcttttgggg aggaaatcat ggaaattaat aaaaaacatt
    52081 ttattcaagt atttttaact tgcttaatct tggtagtaat atgtgaattt atagggcaaa
    52141 gaactatagc tattggaaaa gcctctatag tactgttccc tatgctttat gcagttataa
    52201 ttggacttat aataacacca gatttattag gtaaaaaaat taaagcactt aaaaaagtgg
    52261 ttggagaaaa agaaataaat attgctggtg aagttgttgg aattgcacta gtaatgcttg
    52321 gtataaaata tggtactaca gttggaccaa acattgacaa aataattcaa gctggaccag
    52381 cgtttatcgc tcaagaattt ggtcatatac ttgcaccaat cgttgcatta cctcttgcat
    52441 taatgtttgg aatgaaaaga gaagctgttg gagctactgc aagtataagt cgtgaacctt
    52501 ctttaggagt tatatcagaa aaatatggga taaactcacc agaaggtagt ggtgtacttg
    52561 gtacatattt aatgggaaca gttcttggta ctatatactt tagtgtacta ggttcaatat
    52621 ctatttatag tggtcttcac ccatatgctt tgggaatggc ctgtggtgtt ggtagtggaa
    52681 gtatgatgac agcagctgct ggttcattat ctaccatggt accacctgaa atggcagata
    52741 caatacttgc ctatgctgca acaagcaata tgatgtctag tataacagga attatattct
    52801 tagtttttgt atccttacca tttactaatt ttatgtataa gattttagaa cctaaatttt
    52861 cgagaaataa aaaaactaaa gaaattaaat ctacagaagg agagtgctaa taaatgtttg
    52921 ctaatttaaa tttaaagaaa agttcatatc aattattggt tatgtctgtt attggagtta
    52981 taattcttat aggacaaaga attagcgttg gtacatctat agttacagct cttcctggta
    53041 tggtgatgct aatattagct gctatggcag ctatgattat aaaagattta tttcctaaat
    53101 caatctttcc agcttttgga tttgcaacta taatcggcct tttacttagt atgccatata
    53161 gtccaacatc tgaagtattc ttaactaaca ctaataatat taactttatg gctataacta
    53221 ctccactact agcttttgca ggaatttctg ttggaaacaa aatagaagct ttaaaagaaa
    53281 tgtcatggaa aatagttata atttcactta ttgtatttac aactatattc tttgcatgtg
    53341 cgagtatagc tcatatagtt ttaagtattc aaggtaaaat ataggaggaa tttattatga
    53401 ataaagaaca attaaaatct ctagtaataa aaactataga tgaaaataga gaaaaaatat
    53461 taaaaatagg tcaaggaata tacaaaaatc cagaatatgg atataaagaa tttaaaacta
    53521 cagaagctgt ttcaaacttt tttgagcaag aattaaattt atctgtagaa aaaaatatag
    53581 cagttacagg atgcaaagca gatgcaaatt ctagcaagaa aggtcctcat atatctatac
    53641 ttggagaatt ggatggtata tcatgtaaag aacataaaga tgctaatgaa ataggtgctt
    53701 ctcatacttg tggacataat attcaaatag ctggaatgtt aggtgctgct gttggtttag
    53761 taaaaagtgg cgttttagaa catttagatg gtaaagtatc ttttatggct actcctgctg
    53821 aagagtttat tgagttggaa tacagagagc aattaaaaaa agaaggaaaa ataacttatt
    53881 ttggtggaaa acaagaatta ataaaaagag gttattttga tgatatagac atatctatga
    53941 tgtttcatgc ttctgattta ggagaagata aggctctagt tggtcctgag agtaatggat
    54001 ttgttggaaa aaaggttaaa tttataggta aagaatctca tgctggttct gctccacatg
    54061 atggaataaa tgctttaaat gcagcaatgc ttgctataaa caacgtgaat gcacttagag
    54121 aaacttttaa agagtctgaa agagttagat tccaccctat catcacaaaa ggtggagata
    54181 tagtaaatgt tgttcctgct gatgttcata tggaatcata tgttagagct agaactataa
    54241 atggtatgat tgatgctaat gaaagaataa ataaggcttt gatggctggt ggaatggcag
    54301 ttggagctga tgttgagata actgaaattc ctggatatct tccaatatta cgatacaaaa
    54361 gtcttgataa tttatttaaa aacaatcttg aagatttagg tctaaaagga aaagttattg
    54421 atggtggaga ttttacaggc tcttttgatt ttggagatgt gtctcatata atgcctactc
    54481 ttcaccctat gattggtggt gtaaaaggag ctcttcatac aagagatttt gaaatagttg
    54541 atgaagattt agcttacata attcctgcta aagcaatggc acttacagtt gtagaccttc
    54601 tttttgataa tgctaaggat gctaaagata tattagatac ctttactcca gttatgacta
    54661 aagaagaata tctaacattc ttagaaaaac acgataaaac tttataagtc tatttttata
    54721 atagggtggt atctactgta aaagttatac cactctttgt ttttgtaaca gtatacttct
    54781 tttcttttag tttttagatt aaactaaaat atattatcct ccttaaaact tttagagcta
    54841 cgttgaaata tcagtagaac tatgctatat tctttctaat taatataaat ttctattcta
    54901 attcaaggtg gtgaaaaaat gtttaatgca ggaaatcgaa ttataaatac atggttgtac
    54961 cctattcaag atggctttgt cttgattgat actggatatg aaaatggttt taaacatttc
    55021 aaaaaacgaa tttctaaatt caacataaaa atcaaagata ttcgatacat atttctaact
    55081 catgctcatg atgaccatgt tggttttcta aatcagattc tagacgaatc tcctaataca
    55141 aagattgtta tgcatgataa agctttagaa attctatata aaggtcaaaa ctcttttatt
    55201 ggtggttgta ccagccgtac tgcctttctc ttttgccaaa ttatgaaact atttggaaaa
    55261 ggtgagcata gtttttctcc acttaaacaa gaatttgaaa aaaggtgtat tcttgtgtct
    55321 gacaagaatc gtaaagaaat tgaaaaagaa ctaaatggaa aaattataga tacaccagga
    55381 catactgatg attcaatttc actactaatt gatgaaggtg ttttattttg tggagattct
    55441 gcaatgaatg gatttccaag tactcacaaa attaccatat ttgcagaaag caaactagaa
    55501 tttattcaat cttggaaaac aatcatcaat acaaaaccta aaatgattta tcctggacat
    55561 ggaaaaccat ttgaatacag taaattagaa caaaatctaa tctatgtaaa taaaataaat
    55621 ttatatcctc tacataattc aaaagatatt cacagatttt tgtagaaaat acaaagtaaa
    55681 tttatttgat taattaaaaa atctaacact ttactacgct acttatttta ataacttaat
    55741 cttccactag cttttcataa aattttgttt taaaattaat tttaaagtgc atatgttatt
    55801 taaatacatt agataaaatt cgtcattaat ctacttaaag catatttaac taacaccact
    55861 caaccagaaa attcagaaaa ctgcattgac acaggaaaaa gtttatttta tacttttttt
    55921 aggacatatt gtggacacgt cttaaatcga caaacagaat ttaaattgta agattaacca
    55981 caatacttat tttttaatta tatttttaaa cattagggag gatattatga atgataacgt
    56041 agttaagaag aaaaactttt ttgacaggac attaaacaga atagaaactg ttggtaataa
    56101 actaccagac ccagttacaa tatttttagg gttatgtgta cttttactta tactatctag
    56161 tctagttggt tctatgggta tatcagtagt tcatcctggt actggagaaa ctataaccgc
    56221 tgtaaattta ttgactgtag aacagcttca aattctttta ggaaacatag tcagcaattt
    56281 ccaagggttt gctcctttgg gtctagttct agtaactatg ataggtgctg gtgtatgtga
    56341 caaaacagga cttatgacag caacaatcaa agcatcagta agcaagattc ctgaaacaag
    56401 agtaactctt gttgtaatga ctataggtat gcttgccaat atagcttcag atgcaggtac
    56461 aatattattt ccaccattag ctgcacttgt atatcttggt gttggtagac atccacttat
    56521 aggtttattt tctggatatg cagcagtctg tctaggattt gccgcaaaca ttatgataag
    56581 tgtcaatgat atacttgctg caagttttac agttccagca gctcaaatga ttgattctgg
    56641 atttcaagcc aatgcaacaa tgaacttatt ttttatgata gcatcaactt ttgttctaat
    56701 acttttggca acatgggtaa cagaaaaaat tgtagctcct agatttggta aatatgaagg
    56761 aaatgcagaa ctagatgttg atggaagtct tagtgatgta gaaaagaaag ggcttaaaaa
    56821 agctagtata agtatattaa tatatgtggc tattatagta gctcttagtg taatcggtaa
    56881 aaaaccattc ttagctgacc cagaaacagg agatttacta tcaaacaatg ctcctcttat
    56941 gaaaggtatg gtacctataa tagcactagc atttttcata cctggtgttg tatacggaaa
    57001 aactataggt aaaataaaga aggataagga tgtagtctct ataatggcta gtgcaatgag
    57061 tgatatgggt ggatatataa tactagcatt tgctgcttca caatttttgc aattattcac
    57121 aaatagtaat ttaggtctga tactagctgt aaagggcgga gaatttttaa aatcagcagg
    57181 aataaatgga cctttattgt tgataggatt tattatatta tcatgtttta taaatttatt
    57241 tataggtagt gcatctgcaa agtgggctat tcttgcacct atatttgtac caatgtttat
    57301 gatggttgga tacaatccag cacttactca gatggcttat cgtataggtg attgtataac
    57361 aaatccactt agcccattat ttccgtactt ccctattata ctagcattca caagaaaata
    57421 cgataaagat gctggtatgg gtactgtaat tgctaatatg ataccatact ctatatcatt
    57481 cttaatagtg tggactatac tattaatatt gtttatggta tttaatattc cactaggacc
    57541 tggaatactt ccttcatata gcatgtaatt tatttaaatc tttctaaaag gagaaataat
    57601 ttatgttaga taaaaataga cttataaata attttatgga tatggttaga attgatagcc
    57661 catctaatca agaattagaa atgtctaagt ggttggtaaa ctacttaaaa gaaagaaata
    57721 tagatgccat tatagatgat gcaggtgaaa aatatggtgg taatacaggt aatgtcattg
    57781 cctatataaa aggtgaagaa ggaagtagac cactttgttt atgtgcacac atggaccaag
    57841 ttcaaccttg tttaggtgta aaaccaatac tagatggtaa tgtagttaga agtgatggaa
    57901 ctactacact tggtgcagat gataaagctg gaatagctgc tatacttgaa gctttagaac
    57961 atgttattac agaaaaaata ccacatagag atatttatct ttgttttaca atctgtgagg
    58021 aagctggtat gcatggtgtc aaaaacttta atcctgacaa cttgccttgt aaagatatgg
    58081 tgattttaga ttctggtgga gctattggtt cgatagcata caaagctcct gctcaacaat
    58141 ctataaaaat ctcttttcaa ggaaagaaag cacatgctgg tatagaacct gaaaaagggt
    58201 taaatgctat attagtagcc tctcatgcaa taagcaacat gcacataggc agaatagatt
    58261 cattgactac ttcaaatata ggtgaaatag aaggtggtgg agctacaaac atagtaactg
    58321 ataaggttac attgactgct gaaattaggt ctcatatacc tgaaacttta gagtatgagc
    58381 ttaatcatat ggaaaaatgt tgtaaggacg ctgcatctaa atttaatact acttatactt
    58441 ttgaacataa tatgtcttac cctagttttg aacttagtag agatagtcat gttttcaagt
    58501 taagtgaaga agcaataaga caagttggtg ttgttccaaa tccaatggta attggtggtg
    58561 gaagtgacgc aaatatatta gctaatcttg gatataattg tgctatatta agtctaggta
    58621 tgtatgatgt acacacagtt aatgaatatg taaatataga cgaattatat gatactgcca
    58681 aaatagttta tcatatgatt aaattataaa tatcataata gaactcttta aattataaaa
    58741 ataaaaacct atgtatcctc aactttataa gttatatatt agagttgttt tacataggtt
    58801 ttagtatttt tatataataa tttgttttaa catttttcat aataagcttt gatattttat
    58861 atagtaattt gttctaacat ttttcataat aagcttcaat attttgcata ataatttatt
    58921 ctagcatttt taataatagg ctctagtatt ttatattaat aatttattct agtattttac
    58981 ataattattt gttctaattt ttttcataat aagctttaat actttatata gtaatttgtt
    59041 gtagaatttt atacaatata atgatttata cagttttata aaatatctta aaacagtatt
    59101 tcagtaatat tttttggtct tcctccacca atactagtct cttttgcaca tattcgacct
    59161 aaacctgcat ttactatttt atttaatata cgtcttgcac ttctttcact tacatttaga
    59221 tactctgcta actcttttga atcataaatc ttactttttc tattctcatt tatagcaata
    59281 atttttgcaa ctgactcaca actcattcca gtctttttag atatttcgat taccttttca
    59341 tcagatagca tcaaagaata atttaattca ttttcggaag ctaaaggtcc tcttatgttt
    59401 tcatcttcat ctaccaaata tataccaatt tcttttgaat ctatggagtg tcttaatgct
    59461 ttatgtgcat tattttcagc ctgatacgca gttactccag taccaattcc tatactaaga
    59521 gaaaagccca tgtcttttat ctctctcttt agattgaata gcttatcata attatactca
    59581 ttatcagcta cccctttatg aacaaataca acataatcat ttcttccaag taaaaataag
    59641 gaaccttgaa tgcttcttac atagtttact acaagcttat ccatatctga tttttttatc
    59701 atgtcagaat aatagttatc tatcttctct ttataatcta ttaaactcaa tatttcaaca
    59761 gcaatttggg aaaatcttgc cttacttaga gcatattcac tctttacctt gtcataactt
    59821 tctttgatta attgtatagt agcttgtaaa cgaaatacag gatagcctct ttcttttaat
    59881 tcattatata ctgcaccaaa accagtcaac attatatccg tcttattttc ttcaaataat
    59941 tttatatgcc attctacaag ttcagactct cctacttcca aagaaaatgg attacaaaat
    60001 acactcgttg ctttaatatc aaattcttta agtgcatctt ccacaacata tctatcaact
    60061 acatctatac tgaatttatc taattttata tttgcacttt ttattgccca aaatgccttc
    60121 attatactcg tcccacttct cggtacaaat gaatgtggct tacttatctc atacttagat
    60181 tttataaatt cataaactgc acatcctgta aatataatag catcacattc gtcttcacat
    60241 ttagaaataa cttctattgt atctactact ttttctctta catatatttt agtctttaaa
    60301 tcactgtcta tctgttttaa atcatccttt atcttaaacc cagagtctga aggacctata
    60361 atacccacta tcataaactt cgctcctaat ccataaatat tatacttttt aaaaattata
    60421 tcctcactat tttctacttc tatttaatta ttttgaacta ctccatccta cctacattta
    60481 gaatggaata attagcttat ttttgataaa gtaacttctc aaaatcagca cttggaatag
    60541 gcttacaata ataataacct tgaattacca cacaatctaa agtcactaaa aattcagctt
    60601 gttcttttgt ctctacacct tctgccacta catccatatc taaatctttt gccatggcta
    60661 tagtgtgctt taaaactatt ttttctctgt ctgtgattcc ttcctcatta aagaaaccac
    60721 aatctatctt taatgtatca atattaatat tttttaacat atttaatgaa gaatatgctg
    60781 aaccaaagtc atccatattt aaaacaatac catccattct aaggtcggct attatcttag
    60841 taaataattt tatattttta ataaataaac tttctgtaag ctctaattct aaaaaagatt
    60901 ttggtatact atatttattt attaaactta aaacaatttc tttaaaatgt ggattatgca
    60961 aatgtaatct tgatacattt acagagatag gaactggctc ttcacctaaa tctatccatt
    61021 ttctaatcaa agaacatact tgttcccata catacatatc taatctgata ataaacccat
    61081 tcttctcaaa tagtgaaata aatttaattg gaggtattat acctttttct ggatgaaccc
    61141 atctaaccaa tgcttctgca ccaacaattt tatttgcatt aagattatac ttaggttgta
    61201 aatatacatg gaattgccca ttttcaagtg cgtattccat ttccctttcc atctgttttt
    61261 cttcaagtgc atcatttctt atagtatcat cataaaatat atagttattg atactttgtt
    61321 tctttacttt tttgtgagca tatcctgcca tttcacacgc atttgtaatt ggaatatgat
    61381 tatccaaaat tctataaacc ccaaaacatg gtactaacat atattcaaat ttttttctat
    61441 ttaagctatt tttaatctta taaattacct tatgaatatc tctatcagag taactctcat
    61501 aaaaaatgca aaatacatct gcatacatac gacaacatat accattagaa ccaatgtttt
    61561 tttgaatcaa ctctgcaaca tatattaaag ctttatctcc tcctctaact ccataaatgt
    61621 cattaattac cttgaactta tctatatcca tcattataat tgcataacgc ttgtcaggat
    61681 atcttttaag cattaaactt atttgttcac aaaaactttc ataattgtat agtcctgtta
    61741 atgtatcttt ttggttttta tgtagttgca taagataatc tatatttttt atagcaacta
    61801 aaatatgtgt ttgtttctca cctaacttat ttttactact aatctttaac atataaatta
    61861 atgcccaata gtacttttta tctattccta aacgtctata ctcaaaattt agttctaaat
    61921 cgtcttgctt gctattatta agactatcaa gagattttag aaggtggtta tcattaaata
    61981 atattatatc atcaggatga attaaatgtt tttttatgta tgaaaaagtt ttttcaagat
    62041 tttcctttat aggaaaacta aaaatattgc tctctgattg ataaattgga gtaattaaat
    62101 tcgtatcaat gcaaatagat aaaattatat catatgtatt ataagctaat ttttcataag
    62161 ccttagaata cccttttatc attaaatcat caaaataaac cttatcaact aactctttat
    62221 gtttaaataa aatattattc gtcgaatcag ctaagtcact aattactttc atttcattat
    62281 ttctaagttt gttcttatta taatacctct tcttatcttg gtacattctc tcatcagcaa
    62341 ctttaattag cttatgtata tcaatattat cgtcactcca aatactgccc actgctacac
    62401 tatatatcat ctcatcctta aattcttcac ttaaccaact cactaattct tcaaatagtt
    62461 gttttgatat atcttcacat aatacaacaa actcatctcc tccaatacgg taaacattat
    62521 aagaatgaaa gtattttttt attattacac atgctgacac aatagcagaa tcgccattag
    62581 catgtccaaa gttatcatta atatctttta acccatttat atctacaaat acaactccta
    62641 tggatttaac ttttcctttt tgaaaattat ctatatactt aatatattta tttctattat
    62701 atgcaccagt caagaagtca tagtagctca tataatttaa tttattttct acttttcttt
    62761 ttttcatctc agttaataaa aaataagata gggatgtcaa aagagaggta tctccaacag
    62821 ctttatgtgg attatcaact ccaataaacc ctactacttt atcatcttgt tttagtgaag
    62881 atgtcattaa actttcaatt ttttgaggtt ttaaaatttc atattctatt ggctgttctt
    62941 cttttatatt ttctatatca tcaattatta caaaaccttt ttgttcgaat aataaaaacc
    63001 aattctttaa ttcattaata tcaagatttg ttagtgcctg tttttgttca tcaacacctt
    63061 cattgcacca ttcatatgta ttagttactt tttttctatc ttctgatact tcaaaaacat
    63121 atgctctatc agctttatga aatttaccaa tattggttaa tacaagattt acagcatcag
    63181 aaaaattaga ttctgttata agatgtttaa tacatccaac taataactcc tttatctcta
    63241 atttttctgc tattgactta cttatatctt ccttttctgt aatatcaaga gctatttcta
    63301 atcgtgcatg tttgccctcc catttaatta acttgtcctt taatataaaa tgtctatttg
    63361 ttcgagtatt cgtattttcc catatgtaat attcatcttc ttttaaaata gagtttgtac
    63421 aaaattcgca gggagaatct ttcccctgta atgctttata acattttaaa tgggatatat
    63481 cattaagtcc cattgccttt ttcccaattt cattaatata taaaagttca tatgtatcta
    63541 aagaagaaac atatacaatt tcatccaact catctattaa atttattaca tccatttata
    63601 tatatctcct tttattcatt ttccagattg aatttttaaa gcttttaaaa ttttgctata
    63661 tatttggcaa tgatattata tttctttatg ttttaaaata gtaccttaat gaggttctat
    63721 tttttagtaa atagaattat tattgtgtca atcgtacaat agagttttgt aatacctaat
    63781 ttaatatatt tataattaat tatctcatta tgtgtttata attaattctc atataaatga
    63841 caaatctcca cctcaattaa gtattccaat catatatgaa gataatactt cattcattta
    63901 aaaatataaa actattatat attaaaattt cttcaataat aaattatcta gattgttact
    63961 ttgatatatt atataatatc acaaaggctg atataaaaag acaaaaaggg caattttttt
    64021 atatcaaaaa aaaatgttaa attgatatta tccatatata aattgatatt atccatatag
    64081 atgctatatt taacaattct acttacttcc cttacactta ttagcatata gttattaaga
    64141 gtttgttgca aaacaacact tagcacactt taaaaagtgt ggtctaataa gtaatcaacg
    64201 aagaagacat aataaagcat aaaatatgat atacttttcc acgccatcaa aactgaggat
    64261 tttattatta atatatgcta aaatatgctt aataaattaa attttaatgg gagaatagtt
    64321 atgaaaatat ttagtttctt gttgtttgtg ataggaatat gtttatgtat tgctggattt
    64381 ataggacatt acccagtatt tgttggtaca acattgagtt ttcttgcaat tgcaatgata
    64441 gctgtaagac aagtcaaaac taagaaaaaa atgaaatagg caaatcctaa ctttacaagt
    64501 taatattaca caagtaatta gtctaaaatt ggatactttt tctattacag aaatacatca
    64561 tccactttgt attttcttaa aaaaataaaa tagctatgta aattcaagat tagatagatt
    64621 aactctctat ccatttcatt gtaaaatata catagctatt tgtattcgat ttaaaatact
    64681 tagattttct tacataacaa ataatttcta tctgattatt actcatattc atttagtaac
    64741 cactcagcaa ctaatcattt agtatctatt catccgccat acggtaacct accccaacct
    64801 cagtcaaaat atattctggc tgagcaggat tcttttcaat tttccttctt atacttgcca
    64861 taaaaactct aagcgactga ttttcacttt catagtaatt tccccaaact ttatctatta
    64921 taaacttatg ggttaagact cttcctgaat acttagacat caactcaata atcttatatt
    64981 cgattggagt taaatgtatt tcttcaccat taattgacac aatatgattt tcataatcta
    65041 tctttaggtt tttaacttca aaagactttg gagcatcatt atttatatta tcctgttgag
    65101 ctttatttct aagagccaca cgtactctag ccaaaagctc tgttacacta aaaggtttag
    65161 ttaaataatc gtctgctcct ccatctaaag cttccacctt atccctctca tgctctctcg
    65221 ctgaaacaac aattatttta ttagtctttg cacatgccct aactcgtcct attacctcaa
    65281 tcccatcaat atctggtagt cctaaatcca aaattatcaa atctgggtca agagaatgta
    65341 taagtgatat agctgttcct ccattatctg tctctacaca cctataattt tgagtttcaa
    65401 gagatacttt tataaattta caaattggct tatcatcttc tacaattaga actaatggct
    65461 ttatttccac ttgtctttcc cctcctcatc atacataggt atgctaaatc taaatgtagc
    65521 tcctccagaa ggattattaa aggcgacaat ttctccacca tgagcttcta ctatagattt
    65581 acatatctcc aatccaagac caatacctct tctttcaaga tttctagact tattcttagt
    65641 ataaaaccta ttaaaaatat tcccgatatc ttcatttggt attccttttc cattatctgc
    65701 aacttcaaat agtacttgat ttgactcttt ttttacagtt agttctatct tagaattttt
    65761 aggtgtatgc cttatagcat tatcaattag atttactaac acttgttcta ttaataatac
    65821 atccacatga acgattatta tctcatctgg aatatttgtt tttatgtctc tactattggc
    65881 aaactttttg actcttaata tagattcagc tattatttca tcaacaactt ctggtcgttt
    65941 ttcaatatcc aattttcctt catctattct ggtcatacta agtatattct caacagaatg
    66001 agttagccaa ctcgtatctt catatatatt tttcaataat tctactctag tttctttatc
    66061 tatcacatca tcattttcaa gtattgttga agatgaacct aatatacttg taagtggagt
    66121 tcttaaatca tgagaaattg acctaagcaa gtttcctctt aatctctctc tctctgcctc
    66181 aagatttgct tttttatttt tctcaaataa attttctcta tcaattgcca acgcaacctg
    66241 tgttgaaact gcttctaata gtatcttttc attttctgta ataatatcta tcttaaaaca
    66301 cgcaacacct ataacaccaa gaacatttga ttcttgacct tttataggga aataatatgc
    66361 actgctgttt ttacaatatt ttgtcccaat tccaactggg ttacctgtcc taaaagcttc
    66421 ttttatagct tctttttcta atactgaatg gaatatattc tcacttccat cattgttaca
    66481 aatataaata cttggcttac ctagattatt attctcatct gcaatagtca ctattacagt
    66541 tctatttaat atatttacta aattagaccc acaaaattca ataatttgat ttttattttt
    66601 tgctttaagc aacgttttgt tattctcata gagcaatctt atcatttttt ctctcttatg
    66661 agaaagtctc acttctcttt ttatcctaga agttaaagta cttgttataa ttgctgccat
    66721 tagcataata caaaaggtca taggataatc ttttctataa gctaaaaaag tatataatgg
    66781 atgcgtaaag aaaaaattaa atgatagcac tcctattact gaagaaagta ttccaaaaaa
    66841 atatccatag gttatacttg tagcaaatag tacacctaat atgtatacta gtataatatt
    66901 agattcatta aaacctacct tttcaaaaac tactgatatt ccagtagcaa ttgtcataac
    66961 caatatagtt tttatgaagt ccttaataat tatcttttta ctgagatagc catcttcatc
    67021 ataatcatac tcttttaagt cttcatgttg tagtcgttcc tttttcattt actacaattc
    67081 ctccttattg ttactgttta aattggctct attttatata atacaatttt atcataataa
    67141 attcaatcaa tacatttaat taatgtactt aaattactaa aaggtgctgt cttaaaatga
    67201 aaataaatct ctatttcaaa acagcaccta tatatttaaa ttactaattt agtttttaca
    67261 tacttaaatc aatagtttta ttcaatttca taaattataa tacttcaatt ataaaacatt
    67321 tctatccaac aagcataaat ataaagtggg cacatatacc tgcacataaa ccacctatag
    67381 tatgcgaaag tatcgcttta ccagccaatg gtcttgcatc taaagcatcc atcataccta
    67441 tgtgtgtact taaatatcca ctccaacaca tacccattgc tgtgaatact gctatatcat
    67501 taggagttat agcgcctgat tttataaact ctggtactaa agatattgct gctccaacag
    67561 ctcctaatgc agttacaggg aatgctattg cctctggtga tgtgaatcca aataatggtt
    67621 ctattatgaa gctaatctta tcaccaatag caggtaataa ttttatacct tcatatgcag
    67681 ctcctgtgta aacagcttga cctgtagcag ggtctgtaga tggtccaaaa gttaataaca
    67741 taactaatgt acaaactact aaaactcctg gtattatagc catacccatt tcaacaccta
    67801 acttaccacc ttcaagtata gcatccaatg ttctttggaa tacattacca tctcttattt
    67861 ctctaaactc ttcaagtttt gcacctttat catttatttg cttttcagta tcatttttag
    67921 ggtcataatt ataatacttt ttagtaaaag tcaacataat tctaacacta ataatactac
    67981 ctattattgc cgcaacatta cctattatag ctggtagtac atattcttta ccttgagcta
    68041 tcataaaagt tgttacaata agtcccatac caaaggctgt tcctaaatta cataaagcag
    68101 gtacttgata cttcttaaaa tattgtgtaa atgttttgtc tttagcaaat ggtataatag
    68161 ctggattatc agataaatat gttgcaacta ctcctgctat actagcacca ggtaagcccc
    68221 atataggtct cataagaccc ttaaatatct tattaactaa agatattact ccaaactctg
    68281 aaagcaatgc actaagtgca cctgcaagaa ctgccatagc cattattaaa aatactgtgt
    68341 ctaataaaag cgcatgtgct gtactcatta ttactttaaa catcattcct gcacccatga
    68401 tgcttcctac atatccaaat cctaccgcca atagtacaat aaatacgaag gtttccatac
    68461 ttactgcctt gactcttctc ttatccgaca gcttttccat cttgaaatct tccccctttt
    68521 aattttaaat taaggttcct aacattggta caaatttttt ggtacaaact gagttctaaa
    68581 acttacactc gtaatgcaag ttgtcagttt tttgaaataa aaaaaaatta cgtttataga
    68641 ataagaatat cctctttaat ttggatactc ttattctatt ttatgttatt atattatcat
    68701 ccttttgttt aaaagtcaat tttttctatt tttgttgttt aattttattt atactctttt
    68761 tatatttttc attttctttt atctttgtaa gtactccata taagttgact tttctaaata
    68821 cagtagttat aaataccaat cctaatgcaa ttgaacttgc acacgataat gtactcaccc
    68881 catattctac agcttttata taattattgg tcaaaacaga atacatagta ttatatattc
    68941 cataacctgg tactaatatt attaaacagc aaacacttaa tgtagttgct ggagtcatat
    69001 aaattcttgc acataactca caatatatcg caaaacaaac tgtagctata aaaaaacata
    69061 agttttctgt tactcctata tttaaaagaa atttatatga aaaccaagct atacttccac
    69121 ctattcctgc tagtattaag ttttttcctt tcatattaaa tagcactcca aagcttaagg
    69181 cagtaaaaaa agctgctatt acttctataa acaaatgcac ttatatcccc cctaacttga
    69241 agtacaatcc aagtaccaag aacattccta ctgctataga tacacctaca aaaaatactt
    69301 ctgctaattt tgcaagacca gaaatcaact gtccatctaa caaatctctt aatgcattag
    69361 tcaaagcaag cccaggaact aagagcatta ttgctcctgc tattaaatgg tctaacgtct
    69421 ttatgaatcc gagctttaaa attaaaattg aacaagaagc tataataact gctccaattg
    69481 catttacaaa aaagtcatta agggaagatt tacttaaata cataataaca aacttagtca
    69541 gaatcccaac agtaaatgca gctataaatt cttccacatt tcctccaaat aatatcgaaa
    69601 aagttgctgc tgcaatacct gcaaaaaata ttgttattaa atctgagtaa tagttatctt
    69661 cacttatttc atctaaaatt ttctcacata attcaatatc taaattattt atacttattg
    69721 ctcttgataa tgagttaact tcatgaacca agtttaggtc tactcttctt gagcttattc
    69781 ttttaattgc tgaatgtaat ttcccatcta caaatacaga tgccattaca gctgttggag
    69841 ttgcaaatac atctacgtgg tctattccaa aagattgaca tattctagct atcgtttctt
    69901 caactctata ggtttctcct ccactttgca acatagcttt acctgcattt gaggaaaagt
    69961 ttaaaattct atctatatcc acaaaacata tctcccattc ttttatagta ttattcatat
    70021 tttaatacaa gatattattt atttaaacta ttttaaataa ttcatatcca atatttacat
    70081 tttatgaaaa aacttgtttt ttatgcttgt caaaatcaaa ttttaagctt gtttacacca
    70141 taaaatggct gaattaatat ttgacaaaca ctttcaacca tttatataac cttctaaatt
    70201 gtataacttt ttactacaaa taaaattata tctcttttaa ttctttctct tgagtattta
    70261 gcttatagta acttcatatt tatatatgta caatataaaa cattattttt atgatacaaa
    70321 atataatttg taaatgtata tatgtattaa ctgtgtatat ataaattatt cttgacctta
    70381 tcagtttttt catatatctt catctatacc aaccatatat taataaatga tattacatag
    70441 acttaagtat attaaaaaac ttaaatttag ttatttaaca acataatact ctaatttaat
    70501 ctataaaaat ccatacttaa tataatgcaa ctcttatttt aacaccatct attacacaaa
    70561 acaacatatt aaaaagtaaa atacaaaata tccactataa accttatttt aatactgaat
    70621 atatattata atatatttaa tgtagcttaa atatagttta aacataaaga aaggaaacgg
    70681 tatatgctaa gaaaagataa agttctatta tctctacata aattatgtga aaatatgact
    70741 ttaaaagacc ttcaatcaga taaaacagga ttcactacaa tagaaattgc taaccattca
    70801 tctcttgata gaagtaatac cagtaaagaa ttaaataacc tatacaatga aaaaaaagtt
    70861 ctgaaaatat ctggtaagcc aattttattt ctacatgcta gtattataga aaatttaatt
    70921 ggccgtactt tgaacagtga tgaattttct ataaataatt gtaatgagct acttaaatca
    70981 agtaaaaatg actcagaaga tattttttca acattacttg gacatgattc tagtcttaaa
    71041 ctacctatag aaaaagctaa atctgctata ctctatcctc caaaaggtct taatacgtta
    71101 ctaataggac ctactggtgt tggaaaaagt acatttgctg aaacaatgta caaatatgct
    71161 gtagaaagta aaatcttttc ttctgaaagc aaattcgtag tatttaactg tgctgaatat
    71221 gcagaaaatg ctaacttatt attaagtaat ttatttggtt atgtcaaagg ttcttttact
    71281 ggtgctaata aggataaatt cggcatagtt gcacaggctg atggaggcat attattctta
    71341 gatgaaatac acagattgcc accagaaggt caagagatgc tttttctttt gatggacaaa
    71401 ggcatataca gacgattagg agaatctgac attatgcaca aagctaatgt ctttattgtg
    71461 tgtgccacaa cagaagatat acattcttct ctgcttggga cttttttaag aagaatccct
    71521 gttacaatca acctacctgc tttacaggat aggtctttaa aagaaagatt atctcttatt
    71581 aaatacttct ttattataga atcaaaatac accaatgcaa ctataaaagt tcacaaagat
    71641 gtaattaaat cattactcct ttatgattgt tttggtaata taggtcagct taaatctgac
    71701 atacaactta tgagtgcaag agccttctta aattacaaaa ctggacttaa ggataatata
    71761 gaaatagatt tatcccttgt tcctgattac atctatattg gtcttttaaa attgaatgaa
    71821 aatcgtagta atctaaataa attatcagaa cttgattata tgctttttta tgaatttaat
    71881 ggtaataact tagaagttga atatacaaaa gaactatcta aatacaatat agatacatca
    71941 aacaatggat ttaaatactc tacagagatt ccttatctgg aaaatgatat aaggagtatg
    72001 tttataaatt acatggaaaa gtactctaca aaattacttt cgatatcttc agtaactcat
    72061 tctgattata caagtaatga gatttttaaa gtaatcaatc caaagattta ctatgctgtt
    72121 gaacattctt taaaagaggc tgaaaaaata tcgagaaaca aatacacaaa acaaacttat
    72181 attgctcttt caatgcatat aagtgcactt atagaaaata taaatcaaga cacatataat
    72241 cctaagtaca atttatataa tgataaaatt ttcttagata aagatttaaa tatagctaaa
    72301 atagttttaa gtataattga aaatgactta caaacatctt tacctaaaga tgaagtaaaa
    72361 tttatatcca tgtttctaaa tagcatgtat cttgaaccaa acaatcaatc tgaaagtata
    72421 ggagtcataa tacttgctca tggaaattca acagcaagca gtatgtgtga tgtagcaaat
    72481 tcattgcttg gtacaaacca ttgtaatgca attgacatgc ctcttgatgt aaaagtaagt
    72541 accatacttg ataaaactat agagttggta aaagaatgtg acgaaggtaa gggtgtactt
    72601 cttttaacag atatgggctc tcttatagct tttggagaac ttatttcaga aaaaacaaaa
    72661 atcaaaactc gctcaattga aatggtatct actccaatag ttttagaagc agtaagaaaa
    72721 agtacactac cagaaatgac tttggatgaa ttagctaatt ccttaagctc tttaaatcca
    72781 tatattggac gagcagcaat cgattcaaca gaaataaact atcctgaaaa gtcaagagag
    72841 tatgtaataa taactacttg tataacagga tatggttcag ctatgaaagt agcagacttt
    72901 ataaattctt cacttaaaaa tattagtaaa tacaatatta atttagttcc tcataatata
    72961 gaaagtttta aaatgtataa gaataaattt agtaatacta aaattctggc agttgttgga
    73021 agtgtagatt ttaatgtagc caacacccct tttatacaca tagaggaact actaaatgga
    73081 tatggcctag atatgctaaa caaaataata gaaggtacat tcaatgccaa tagtattaca
    73141 aatataaaag aaacaaatct atcatacaac agtttaataa taaactttat gacccaaaac
    73201 ttagagcttt tggactctgt taaattattc aactatgtca attcttcctt atttacaata
    73261 atagaattaa tagatgaaaa cttaaagagc aaatttaagc taggatatat actacattgc
    73321 tcttttatga tagaaagatg ttttaaaaat acaacttttc catataataa cattactgaa
    73381 ttaattagta aaaatcatga actatatagt ttaatacgtg aagcctttaa gccaacagaa
    73441 gcttatttta atattttgat accagacgaa gaaattgctt atataataga catgattaat
    73501 gagtatctaa ataaataaaa tttatagcac ttattttgtg catattaatt aatatatgaa
    73561 atggaggacg agattttgaa aggaaaaata aaacagttaa caatacttgc attaattttt
    73621 atatttataa ctcctgtatt tgcatttgca gatactccac cagtaccaaa ttcttcaaga
    73681 gcagcactac ttatagacca ggaaactaaa agaatattat ttgaaaaaaa cattgatgaa
    73741 aaaatgccat tagcgagttt aagtaaaatg atgacctttt tattggcaat agaagcagtt
    73801 gataaaaatc aagttaaaga gactgatatg gtgaaaatag acaagtctac agcttcagta
    73861 ggaggttcta cttgtaaact taaagatggt gatgaaatat ctctaggaga gcttatgcag
    73921 ggtctaatgc tagtatctgg aaatgatgct gctatagcca tagctaaaca tattggtaaa
    73981 actgaaaaga attttgtaaa tatgatgaac aaaaaagcag aagaaatagg aatgattgat
    74041 acgtattatt ttaatccaaa tgggcttcct atatatactg acccagaaca taaagaacct
    74101 cctattgaaa atatgtcaac tgctcacgat atagttacac ttggaaagta tatgtacgac
    74161 cattatgaaa atcaagttac aagaataacc actatgcaag tatataatga tactaaaaag
    74221 gattttacac attataacac aaatcctctg cttgtttcag tacctggtgt tgatggaata
    74281 aagacaggat atacagataa tgctggatat tgccttgcat tttctatgat ggtacctaaa
    74341 gatgctaaaa acgaaagaaa tcatagattg ataggtgttg tacttggtga tggtaacaag
    74401 aaaaatagaa tttcttcttc cgctacttta ttgaaatatg gtaaagataa tttccattct
    74461 aaaaagatag cacataaggg tgatattata gagactcctt gtgttgatgg tattgatgat
    74521 tttaagataa cagttaaggt tgataaagat ttgtatggtg ttgtttcaga taacgaaaat
    74581 atcaatccta aggtagtgtt taaaaatatg aattatccta tccataaggg agatattgtt
    74641 ggtgttgcaa agtattataa tgactctggt aaatttgttg gaagtgttga tgtaaaaagt
    74701 gaaagtaata taggatgtat tcctttgaag gataagatta agattaaggt tgctaagata
    74761 aataaaaaac ttgagattaa aaattctgtt tgttttaaag catagtaaag catattatta
    74821 aaagggtatg ttaaatttat aaagactcca ctttgtggag tctttttgtt ttttacaaaa
    74881 aattaaaata gtggcaacaa ttgaggatgt gagggagagt tgccactatt ttgtataggg
    74941 tattatatta tgtttttaag ctagttttac tatcttctat gtttatataa taactcttgt
    75001 gtgtgaattt aattgataat taatatgaaa attatgtgaa gttttgattt atttgtaata
    75061 tattctacta ctattataat ttttctactg gatatactaa tcatttgttt aacattatct
    75121 gagattgatt tgcaaacttt tatataacta aattagttat ataacttata gattccatta
    75181 aataccctaa taatcatata tgtacataca aagtcatgct tatgcaaaat ctgcagtttc
    75241 aactaactta ttatataaac catctttatg tagaagttca gcatcatttc cagattctat
    75301 tactctacct ttatctaata catatatatt atcagcactc ttaattgttg aaagtctatg
    75361 agctattata ataactatct tatcttgtat gtactctttc aagttgttca atatctcttt
    75421 ttgtgaaata ttatctagag ctgaagttgc ttcgtccaga ataagtacct ttttattact
    75481 tactaaagct ctagctattg atatacgttg tttttgacct cctgatattt tgacaccttt
    75541 ttctcctact acttcgtcca atcccttatc tagatttttt ataaaatcat ctaaacaagt
    75601 aacttctaat atctcatcta attctttatc acttatttta ttatttaata ctatattatt
    75661 ttttattgtg tcatcaaata caaattgatc ttgagttact atatcaatat tatttcttag
    75721 tgattttaaa ttaatatcct ttatattaac accatctatt aatatatcac cttcatttat
    75781 atcccaaagt cggtatatta gatttgttat tgttgatttg ccacatccac ttccaccaac
    75841 aattcctgtt acttcccctt tctcaaattg taaatttata tcatttaaaa caaggtttaa
    75901 atcctcacca tatctaaaag atacattttt aaaatctatt ttcttaattt cactgttatc
    75961 tattctatat ccattattat caactttaat atctatcttt tcatctatta ctgaaaatac
    76021 tctattgata gacacttttg attgtgctat tctagtattc gcccttacta tagctataca
    76081 tggtccaatt aacattcctg tatattgttg aaatgctatt aactccccca tcgtcatctt
    76141 attatttatt attttatatc ccccaattcc atatattaat attgttatca atcctgttag
    76201 tatttgagat attgctatat tactactcat aatgatgttc aaattcaaat ctttttttat
    76261 caaatctctc tctctcttta aatacttatt aaagaaattc ttttttgaat ttaatataac
    76321 aatatccata atattagata cgtactcttg aatcaaattt gataaactgc ctgaatcact
    76381 tcttatttca gaaattttct tagatataag ttttgtcatt ttattttgag aaaatgttaa
    76441 tatcaactgt aaaaataaaa ctactaaaaa taaatcaaac tgcaaattaa ttaagaaaat
    76501 taacgatatt atagctgtaa acacatttac aataatatca aatataatct ctgctccaaa
    76561 gttttctatc ataaatatat cactttccat aatggataaa atattacctg ttttcttact
    76621 tgaataatat ctaccagaaa gttttgatat atggttaagc aactttactt ttagatttat
    76681 agtaacttta ttttttattg aagtatataa atatgataat ataacatcaa atgtagctga
    76741 taatatcctt ataaaaatat atatcaatat taaatttata agcagaaaaa tatttttatt
    76801 tcctattcca tcatctatta tacatctaat tagttgaggt attacaatat ttacgccagc
    76861 aattataaaa accattataa atgatactat caacttagtc ttattcttat atactattat
    76921 atttagtatt ctaaataaat tattattaat agtttttttc atctattttt ccatctttta
    76981 tagttataat tctatcagct gtctttgcaa tattatcatt atgagttatc ataactagtg
    77041 tttgtttgta ctctttaaca caccattcaa gcatattcat aacttcattt gtagtcttac
    77101 tatctaagtt gccagtaggt tcatctgcaa atattactga cggtctattg gctaaagctc
    77161 tagctattgc aactctttgt tgttgacctc ctgatagttc attcggatat ttctttattt
    77221 gtttttcaat ccccaactta ttaattaatc tcataacata ttctttatct tcttttttcc
    77281 catcaagcaa cacaggaagt actatattat catatacatt tataactggt attaaattgt
    77341 aactttgaaa tatgaagcca aattcctgtc ttcttatttc agacagctta tcatcattta
    77401 atgtatataa atctacatca tctaagtaca cattccctaa agttggcttg tctaagcctg
    77461 caacacagtg aagtagtgta cttttaccag aaccacttgc acctacaata gctgtaaatt
    77521 tatgtggctc tatatctaaa tcaataccat caagagctct aacttcattc tcatattttc
    77581 catatatttt ttttaaatct tttaccttaa gtattttcat aacgtatctc cattcccatt
    77641 taaaaaacat atatttttaa attaaatttt cgtaaataag atctactgcc atatctaaat
    77701 tctctaattg atataagtat acttctttgt agtcaatact aatattaaac tctttattta
    77761 aaatagttaa aaaattatat gcattataat ttccaataca tgtaaaattg ttaaataaag
    77821 aatattcact tacaaattca aagtctattt ttattttaga aaagtttcta tttatcacat
    77881 ttattatttt ccttgctata tccaatctta tcaaattaga tttataactt ggagtgttca
    77941 agttttctat ttttaaatct tctttacttt tgcttttttg aataagtatt tcttccaatt
    78001 cattaaactt aatatatgga ttgtttttta atatatttgc aacaatgcca gttgccactg
    78061 cacaagcctt actattttta ccaaaatgag ttactttatc tttaaattta ataaaattat
    78121 cttttgaatt tgcatacatt tgaatcttat tttctggttc gtatatatat tgattatttt
    78181 tatatatatt ttcattacct actacaccaa taacactttc aaatatagta ggaatacttt
    78241 ctttatcttc atatttatta tgttttgaac aaataataaa tctaccttga ctatttaaaa
    78301 tattacaaac cttttctaat tctttttcat acatactatt aatagatgca gctgaaatgt
    78361 ttattatctg tatatccgac atagtcaact tgctcagtgt actaagaaga tttaaagaac
    78421 ttgtttttcc agaatcatta aatatattaa taggataaat ttgggtattt ttacttatat
    78481 ttaatatggt tttcgataca aaagttccat gtccatttat gtcatttatt tccttccccc
    78541 ccaaatcttt caattgaaaa tttgaatcat aaacataatt tccattaata tcatcatcat
    78601 ttacatctaa tcctgtgtct aagactgcta ttcttacttt agtcaattaa taatcacctc
    78661 taaaataaat taccttgaat ataaaactaa tccttaccat aatataggtt ccaagatgtt
    78721 tttcattttt ttacaatttg catcaaacat ttttttgtta ttttttaaag tatatatttt
    78781 cgatggacaa gttgtacaaa ataaatttac tttacattct ttacaactct caatatttac
    78841 tggttttaat ttatcaaata tattaaatat atccatttct ctattaagaa tcctctctaa
    78901 tatgttttca ttaaattcta atatattgaa tatctttaaa tccttatact ctaagtttgg
    78961 acacggatat acatctcctt tatgatctat acttatctga ttaacacctg ctttacacat
    79021 atttgaacat aaactacttt catccacata atcatctttg caaatgtaat caatatcaag
    79081 tttatcatta agatatttgc tatagttctc attacctcta ccaatattca taaaatttct
    79141 tattataggc gttgtaccta aatcttcatt taatttattg aatttctcta tgtctttctc
    79201 attattcttt cctaccacca tagacaaacc tacgttctcg aattttttta gttttataag
    79261 tctaatcaca tttaatactt tacagaatac tcctttacct cttacttcac tacaacttaa
    79321 ttcatcataa ccatctaaac taatttctat tgcatataaa ccattaatta tatcatcaat
    79381 ctgtttttct ttaattaaag ttgcatttgt agacagaatt attttacctt taaatttttc
    79441 ttttatataa tccaacagct ctaagaaatc atttctcatc aatggctctc cacctgtaat
    79501 ggttaatatc cttggattta atttaactat attatctatt acttttctta cttgagatgt
    79561 atctaaataa tcgttattat ctattttaga atctacacag caataatcac aacttagatt
    79621 acatctatta gttggagaaa atgaaatttt gtttattctc tctagtctaa attcacttag
    79681 aatagaatca cttagaagtc ctatatgctc taacttatct ataactcgtt cataatattt
    79741 tttatcttca ttttcttgga atacatcata caaattacca agttgtaatg cattatctac
    79801 tgaatacttt agaacttcat aacattctat tggaatttta acccatcttc catttacttt
    79861 attactaaga ataacttgat tattatttat tattttttca catatacaat ctaaaaaata
    79921 tttgtttgag ctattcattt attttatttc cttcctatat atttaaatta gaaatttcat
    79981 taattttctt ttataccact tactatacta agtttattta tcattttatt agaaaaataa
    80041 actgcaatga cacaaacaaa aacagatata gatccaaata ttagaatttc atatattgga
    80101 atttcaaatt taatagagtt atttatacca tatacctgtt gattaagttt gttagtttca
    80161 gaaactattt tataataatt gaaactagat ataattccag ctacaatcat acttaatacc
    80221 ccatatatca tattttcttt tattaacatt ctttttacat tttttttgga catccctatt
    80281 gctctaaatg tacatatctc actcaacctc acaattatat ttgatctaac tataaaaata
    80341 atgtttatag atgatattaa taaaactcca aatacacaaa tcattgctaa tttatatgag
    80401 gatttattat aatggtctcc aaaatgatta cgtacatatc ttccctctat atctgaaaat
    80461 ccactttttt ctattatatt atttatttct tttattactt ttttatctgt ttcttttttt
    80521 atcttcacaa aaactttatt ataatcactt atccctgtta attcttttaa atccttttca
    80581 ttaaatataa tttgaattcc acctgattga gattctccat cttgctctga tatatagcta
    80641 tttttcatta ttccagcgat tcttactttt gtatttatat atttatactc tccatcttta
    80701 tatacaggaa tttttatatc tattaagtct cctattttag gtgattttat aatctgagta
    80761 ttatttgaca atttaattct agaataaaaa ttatttacca ataaaacatt tttataatcc
    80821 ctgtctgtat aactataaac attttcgcct ttatctatat atttatctat attatttaat
    80881 agctctttat tgtaacctcg aattaaaact gtagactcat tattattatt tatttcagtt
    80941 ctttttagct catctaaata atcttcttct aagtcagcat ttcttagata tccttttaaa
    81001 taaatattgg gttcaacatc tgttacatct tcaatagctt ttatttcatt taataaagaa
    81061 ttatcatatt tagaaaatgt ataatttgca tttattggtg aatatcccaa ataaatatca
    81121 aaattgccat atgatttact tgttatatta gctgaatctg actcttttcc atatatgaat
    81181 tttgtagaag ttagtctgcc tataaataaa accccacata gtgatatcgt aattattatt
    81241 attattgatg taaccttatt cctaaatata tttttaaaag ctatctcatt tataattcca
    81301 acaacttttt tatgtgattt taacaacaaa agcctaggaa tataatttaa cttatctgtc
    81361 ttttttatag catcaattat agataaattt ccagctttat atattggtac tacagaggct
    81421 aatataactg ctataattga catgatgata gattcaatta tagagtttgt atttatagtt
    81481 aattctgcac ttttatcata tactatcatg agacctaagt aagaaaaaac tatacctcca
    81541 agtaaaccaa ttactatacc tacagataaa actacaatac tctgaataaa aaatacctgt
    81601 ctaatatttc tcttgctagc tccaacagct ctaagtaaac caatttgctt ggtcatatct
    81661 agtattatta tgttaaacat attgtatatt actaatgttg cacataataa agggagtaag
    81721 ctttgcttta ttgaataagt tgtttttttt gaaatatttt tcatatacat agacatactt
    81781 acttctgtat ttggataaaa ttgattactt gttaacttat attttctccc tagattcact
    81841 actttttgag aatctaaatc ttttgtattc aattttaatg tacccatatg agttattaat
    81901 tcatatggaa caatatcttt gccattgttt gaatatgtaa aagctcttac cttatattta
    81961 tttaaatttt catagtattc atcagattta cttaaaatac caactatttt aaattgctta
    82021 tctttactat aaatagaatt ttcattattt ttatttatat gctcattaac aatctgaaaa
    82081 tcaatagttt gatttaattt gacatctaat tccattttgt ctaaaacttt ttgttctatt
    82141 actaattcat tagaagttct aggctctcta cctttaacta acttatatct agtagaatct
    82201 aaaaaatctt tattgtaaga gcataaattt agagatgctc cattatcttt acttataatt
    82261 tctccaaatt taagtacatc attgaattct tttatatctt cttcaccatt aagttctttt
    82321 actatatcac tatttatatc ttcataaaaa gcatgataat ctcccgagtt tttgtatgca
    82381 tgatttatat ctgattgtcc ttgagattca ttaataacac ttaatgaaaa aactagcata
    82441 acagcaatcc ctatactaag tattaatgat aaagtttttc ctttttgtct ctttaaatat
    82501 gacaccgcaa gtttaatatt tatcataatc agaatcctcc ttattcatat ttacaagaaa
    82561 aactctataa cctaaaatag taggttatag agcactattc attaaatact aactaactcg
    82621 ttgtgctagt taaatttaat tattaaaaat actagagttg agaaaatcac atttcatttg
    82681 taaaaaacta catctagtac tttcaacata tttaatagac tgattagtat tttttaataa
    82741 gctactgttc cttttggagt tgatcctgca caatccacca tacagtctat ttgtgaaatt
    82801 attccatgct tatcataata ccatttacat ggatctgctt gcacctcaac atcttgaagt
    82861 tctatttttt cttcgatttt ttttatatgt atcataatac atatccccct ttacttttgt
    82921 tttatattta ttataactag ttaaactaga ttataaacta catagttttt ttgttgtttc
    82981 cacataaact ctttctaatc cacaataaat tggtactgca ctttggaatt tacctgttac
    83041 ctttttattg ataagtttac atctggttga catacaataa tcaagtctag tacatccatc
    83101 acactcttca ttcttagata tataaatttt tataaggttc ttaatttttt tatcatctaa
    83161 tccatcatat atatttccta gtaaaatatc tttatctcct acacatactg tacatggata
    83221 tacatctcct ctagtatcta ttgcataact atttatccct ccaaaacaat ctcctttttt
    83281 cttatttata aattgtttat ctaaaataga tatatctata tcaggataat cctttttaat
    83341 attcataatt ttactaattt gttcatttaa tattttaata tgagaattat cccaattttt
    83401 atccataaaa tctgaaattg gtgcgatatt tttaaaccct tgttttgcta tatcatatac
    83461 actctcataa agatacttaa cagtatttga gttatatgtc attcttgccc taacatatat
    83521 acctttatct ataagtcttt ttccattttc cattactttt tcataagtac ctactccgtt
    83581 agcatctatt ctatttatat catgtatatt cttttttcca tcaatactta tcgatatgtt
    83641 ttttacattc tttgctataa actctattat ttcatcattt ataatagttc catttgtagt
    83701 tatatcaaat aatatctttt tgtcactcaa tctatctact aaatccctat gtatatattt
    83761 aatcaaatca aaatttataa atggttctcc tccatgtaaa acaattgttg tataatcact
    83821 attactttct aattctttat tacaaataaa atctattgtt ttatcagcag tttcataact
    83881 catattttct ttttttttat cattaccttc ataacaatat gtacatctca aattgcagtc
    83941 ttcagttaca aatatagtaa atttcaatta actttttcat ctccccatac agctgtattt
    84001 aaattgtgtt tcatcatact acaccatcta tccaattcca attcattatc cttaactgaa
    84061 tctaatatcg ctgggcaatg ccaacaaaaa atatttacat cacaatcttt acatttttca
    84121 aagttatatg gataaatact ttctaattta atcaaagact ttagatctct tgttttattt
    84181 tcttttataa cttttacaaa ttcattgtca aatatatttc ccattttata gtcatccttt
    84241 atcagtgaag gacaaggata tacatctcca tcataattta taaatatttg agagtttcct
    84301 gcattacatg cacaacatcc cattttttta ttttttttat ctttacacat ttttaattca
    84361 ttatctaaaa tatacggaat tgtaattgga agaactgtat cttcaattaa atagctttct
    84421 ttattttcta ggcctcttcc tgttggaata aaatatcttt caacaaattc tgttccaagc
    84481 tttttattta aatctttaaa ttgtttattt aaatgagaat ttttttgtcc aaataccata
    84541 gacagcttta tattactgaa tccattgtct tttagcagat taacagagct tattacttta
    84601 ttaaatacac cttttcctcg tgtttcacta caagtatttt catctactcc atcaatacta
    84661 atatctattt tttcaaaatt agttataata aaatcaacat tatgttcatc tattaaagtt
    84721 ccatttgtgg ataatattaa tttggtatca ggtaattttt gttttatata tttaattatt
    84781 tcaaaaaaat cttctcttat caatggttct ccaccagtta taattatatg aggagtattt
    84841 aaaactgata ttatatctac gatatttttt aaatcatatg tactaagtaa atctttctta
    84901 ttagaagaag attcaacaca acaatgttta caaaataaat tgcatctatt tgtcaaacaa
    84961 aaataaattg caacaccatt gcttaacata tcaaagttta aattgttact tttaaaaatt
    85021 tgatttttgt tcataatatc tataagatta ataatatatt ttttgtcact ttcatcatca
    85081 aaataattta caaaatcata aatttttatt ttattttctt gtcctaaaag aaaatactta
    85141 tatatttctt cagacaattt aatatatttt ctaaatttct tattataaat aattactagt
    85201 tgattttttc tataaataat taaatcttct acattaaaaa tcatttcttc agaatctatc
    85261 acaactaagt cctcctcaaa ttagtaaaat atttttcttt aatatttatt actaatatca
    85321 actttactat ctaattagtt atttaattgt tgtttttatg ttcctagtta taaagtttat
    85381 caaatttaca ttttattttt ttatactata tagaactttt ggtcaataat gttaccatac
    85441 taaggtcgca tttgcagata aaaataactc tatttttcta aatttattta agatatatca
    85501 tgcaaataat ataactataa aacctatcaa cattttaaat tcaaacaaat ataaatcaca
    85561 ttttttgttc tattatttta ttgagtacta aaaaggatgt tatcttatta gcatagcatt
    85621 caaccatttt tatcacctcc aaatatccta tgccttaaag atagcatctt ctattttatc
    85681 tttcaatact actgctccaa ctgggcaatt tagagcccca actagaatta gttcctagtt
    85741 aatggtatat aaatagtaat tgtaaacttg tttttatctg agtatatttc cacatttcca
    85801 ttatattttt ctactgaact ttttacacta cttattccta ttccatgtaa aaaggaatct
    85861 ttcttacttg taataacctt attatttttt aatacaactt catttatctt tgtattttca
    85921 cattttatta caaataacct atttataaca gttcctctta atttaatctt tttttgtata
    85981 cttgtgtcct taatcttaat acaagcttct attgcattat ctattatatt tgaaaatata
    86041 ctacatatat ctggcatctc tataaaatta cattctaaaa aattaatatc tactagaaaa
    86101 tatatattat tcatatcaca aatagatttt ttatcactta aaataacatc tagaatcata
    86161 ttctgagtat taaatatagt attacattct tttatttgct tatttatatc tttaatatac
    86221 ttatctgcaa actcattttt cccataaaca ttctgaatac aaatgatatg attattcata
    86281 tcatgatata gttttcttat tttcaactga tattcctgta aatttaaata atatttatat
    86341 tgcatattca ttcttttttt tgtaatttca tattctatct ttaaactatt atcttttatt
    86401 attcttccta ttatgcttac taatgaaaga tttgatagta aaaatacagt tgatattgta
    86461 agtattatta aactctcttt agaatcgata atcttatctt taaaaataaa ttcaaatatt
    86521 actattacac caataatgtt tgctattaat ggaatagata aatatataca atccctcttg
    86581 tttatttttg tttttaatct gataaactta agcaatggta ttaatactat tagtaatgat
    86641 ttagatatca ttattaactc taacttcaac aaattatcct ctaataaatc attcatattt
    86701 tttatagaat taagtgtcat tactatactt aatccaatac tatcaaatcc aattaataac
    86761 atccaatata gcaaacttat aaatacactt ttccatttat ccactacata atttatttta
    86821 tacaatacat atgtaataaa tatacatata aataatttaa tatttatatt aaactcaatt
    86881 gtattcaaca tagtaattat cataatagca attactatgc tactatttag ggttaatcta
    86941 ttctttctta actcactaaa ttcatttaat aaaaatttta atacaatcca ttctatcgcc
    87001 gtagaaaata taggtaaaaa aatccaaaat acatttatat ttaacataat acatctccca
    87061 atacatatgt taattttttc tttaaattag ccattctata tttactaact ggtatatctt
    87121 taccattaat aactacagta tttttacata taaattgaat atactccaaa ttaattaaat
    87181 agctcttgta acatttttaa aaatttattc tttcttaaat cactgaattc atttgataaa
    87241 aattttaata caattcattc tatcgccgta gaaaatatag gtaaaaaaat ccaaaataca
    87301 tttatatcta acataataca tctcccaata catatgttaa ttttttcttt aaatcagcca
    87361 ttctatattt actaactggt acatcttcat cattaataac cacagtcttt ttacatataa
    87421 attgaatata ctccaaatta attaaatagc tcttatgaca tctaaaaaaa ttatattttt
    87481 ctagctctaa ttctatttta tccatactat ttttagtata ataagtatca tttttagtat
    87541 gtatagtcaa aacctttttc ctaacctcta tatacataat actattaatt aaaattttat
    87601 tgattatacc tttattttct atcagcataa aattttctct tttttttata atatccgata
    87661 tacaactcaa aatactttca tttaaatctc caaaatctat aggctttaat aaatatctat
    87721 aagcccttac cttatagcct tcctgtatgt aatcaactat tgaagttata aatattattt
    87781 cagaagtatc attagtttct ctaattattt tagccacatc catgcctgtt agttgaagca
    87841 ttttaatatc taaaaaaaat atatcaatac cttctaaatt tgtttccaat aattcttctc
    87901 ctgaattaaa ctcaaatagt tcaatttgac tagaaatacc ctctaaggac tttaatatac
    87961 actctcttaa aaaagctatt tgtgtaatat catcctcaca gataactatt ctatacataa
    88021 acacccctcc ttagacatta gatctgaaaa caaataaaat atcaatttat aaataattat
    88081 ttagttatac aactaacatg gtcatcaaat actattattc acttaaaaaa tcacccccta
    88141 tttttagtat gttaacaaca aaataagaag atatcttaga tttttaaaaa caattaatac
    88201 ttaatgtagt tttgtatact atttataggt aattttttat atcattttaa acattaaaat
    88261 tattgatgtt taagaactat tatattgata gtaatatata attaatgata tcaaaaattt
    88321 ttaattagac ttctctctta ttcaagattt ttctatataa aatctaagaa taaatagaaa
    88381 actaacatct aaccttttat tttttatttt cgatctattt acttgaattt taacataaat
    88441 ctatctttta gtatatatta atcatgctga atttgtgatg acatgtatac aaaatatcgt
    88501 ttagtatttt ctaataaaaa atattactga aattaaaaat ctacaatagc atttaacaag
    88561 taaaaacatg tttacacaaa tatataattt aaggtcttta aaatagagta tgtattattc
    88621 taaaaattag ttatagttat cacataaaaa tagaaaagaa ttttcaaaag atttaaagaa
    88681 catatatact tcaattgcag aagatgtaat gttaagtgaa ctagcattct tcgaggaaaa
    88741 atagactcaa aaaattagaa aatagaatca ggttttagat gatttaagta tttattttca
    88801 aaaaagaaat ttgattctaa gttaataaag aaatatttaa aaaaatcaaa aaattttctt
    88861 aaataagtaa taggttttgt aaaaatggaa aaatatcaaa ataagactat gatttttaaa
    88921 actatagcct tatcaataaa tttttattta aagaacacac ataaatattt ttaaacctaa
    88981 tttatgtgaa gttttatgta ttttttatat aagtagtatt ctaatcttac tcatctaata
    89041 taccaaaaag actgtaagta agttcacttt tatgcaaact tacccacaat ctcttttaca
    89101 cattaattct atttattaaa attaaaaata tttactgcta ttctacccaa taaagatgat
    89161 actgttg
//
LOCUS       DAEHWO010000007        89074 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEHWO010000007 DAEHWO010000000
VERSION     DAEHWO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 89074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89074
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.007"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(216..1097)
                     /locus_tag="KNP54_000667"
     CDS             complement(216..1097)
                     /locus_tag="KNP54_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBF0891596.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            1553..2527
                     /locus_tag="KNP54_000668"
     CDS             1553..2527
                     /locus_tag="KNP54_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891597.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(2643..3704)
                     /locus_tag="KNP54_000669"
     CDS             complement(2643..3704)
                     /locus_tag="KNP54_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBF0891598.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(4316..5167)
                     /locus_tag="KNP54_000670"
     CDS             complement(4316..5167)
                     /locus_tag="KNP54_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0891599.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(5184..6104)
                     /locus_tag="KNP54_000671"
     CDS             complement(5184..6104)
                     /locus_tag="KNP54_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBF0891600.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIKGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(6214..7128)
                     /gene="murQ"
                     /locus_tag="KNP54_000672"
     CDS             complement(6214..7128)
                     /gene="murQ"
                     /locus_tag="KNP54_000672"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBF0891601.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(7227..8324)
                     /locus_tag="KNP54_000673"
     CDS             complement(7227..8324)
                     /locus_tag="KNP54_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBF0891602.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(8557..9903)
                     /locus_tag="KNP54_000674"
     CDS             complement(8557..9903)
                     /locus_tag="KNP54_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0891603.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(9992..10300)
                     /locus_tag="KNP54_000675"
     CDS             complement(9992..10300)
                     /locus_tag="KNP54_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891604.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(10563..10961)
                     /locus_tag="KNP54_000676"
     CDS             complement(10563..10961)
                     /locus_tag="KNP54_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891605.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(10963..12123)
                     /locus_tag="KNP54_000677"
     CDS             complement(10963..12123)
                     /locus_tag="KNP54_000677"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBF0891606.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(12554..13573)
                     /locus_tag="KNP54_000678"
     CDS             complement(12554..13573)
                     /locus_tag="KNP54_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0891607.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLIKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(13567..14247)
                     /locus_tag="KNP54_000679"
     CDS             complement(13567..14247)
                     /locus_tag="KNP54_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891608.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GVGYIIQC"
     gene            complement(14399..16306)
                     /locus_tag="KNP54_000680"
     CDS             complement(14399..16306)
                     /locus_tag="KNP54_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0891609.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAMFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(16307..17059)
                     /locus_tag="KNP54_000681"
     CDS             complement(16307..17059)
                     /locus_tag="KNP54_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891610.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(17375..18529)
                     /locus_tag="KNP54_000682"
     CDS             complement(17375..18529)
                     /locus_tag="KNP54_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0891611.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(18532..18999)
                     /locus_tag="KNP54_000683"
     CDS             complement(18532..18999)
                     /locus_tag="KNP54_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0891612.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(19013..19501)
                     /locus_tag="KNP54_000684"
     CDS             complement(19013..19501)
                     /locus_tag="KNP54_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891613.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(19515..20846)
                     /locus_tag="KNP54_000685"
     CDS             complement(19515..20846)
                     /locus_tag="KNP54_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBF0891614.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(20860..22425)
                     /locus_tag="KNP54_000686"
     CDS             complement(20860..22425)
                     /locus_tag="KNP54_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBF0891615.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(22595..23380)
                     /locus_tag="KNP54_000687"
     CDS             complement(22595..23380)
                     /locus_tag="KNP54_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0891616.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(23547..24746)
                     /locus_tag="KNP54_000688"
     CDS             complement(23547..24746)
                     /locus_tag="KNP54_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBF0891617.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(25268..26605)
                     /gene="xylA"
                     /locus_tag="KNP54_000689"
     CDS             complement(25268..26605)
                     /gene="xylA"
                     /locus_tag="KNP54_000689"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBF0891618.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(26701..28251)
                     /gene="xylB"
                     /locus_tag="KNP54_000690"
     CDS             complement(26701..28251)
                     /gene="xylB"
                     /locus_tag="KNP54_000690"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBF0891619.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVSSLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSKVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            28459..29619
                     /locus_tag="KNP54_000691"
     CDS             28459..29619
                     /locus_tag="KNP54_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBF0891620.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(29775..30179)
                     /locus_tag="KNP54_000692"
     CDS             complement(29775..30179)
                     /locus_tag="KNP54_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0891621.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNANLLSDDE"
     gene            complement(30200..30682)
                     /locus_tag="KNP54_000693"
     CDS             complement(30200..30682)
                     /locus_tag="KNP54_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891622.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(30702..31511)
                     /locus_tag="KNP54_000694"
     CDS             complement(30702..31511)
                     /locus_tag="KNP54_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBF0891623.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(31504..32283)
                     /locus_tag="KNP54_000695"
     CDS             complement(31504..32283)
                     /locus_tag="KNP54_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0891624.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(32283..34361)
                     /locus_tag="KNP54_000696"
     CDS             complement(32283..34361)
                     /locus_tag="KNP54_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBF0891625.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(35160..35681)
                     /locus_tag="KNP54_000697"
     CDS             complement(35160..35681)
                     /locus_tag="KNP54_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBF0891626.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKIKDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            35847..36413
                     /locus_tag="KNP54_000698"
     CDS             35847..36413
                     /locus_tag="KNP54_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBF0891627.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(36630..38693)
                     /locus_tag="KNP54_000699"
     CDS             complement(36630..38693)
                     /locus_tag="KNP54_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBF0891628.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYSNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(39074..42409)
                     /locus_tag="KNP54_000700"
     CDS             complement(39074..42409)
                     /locus_tag="KNP54_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBF0891629.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMMDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTENFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(42459..42887)
                     /locus_tag="KNP54_000701"
     CDS             complement(42459..42887)
                     /locus_tag="KNP54_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891630.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(42877..43257)
                     /locus_tag="KNP54_000702"
     CDS             complement(42877..43257)
                     /locus_tag="KNP54_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBF0891631.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(43290..44462)
                     /locus_tag="KNP54_000703"
     CDS             complement(43290..44462)
                     /locus_tag="KNP54_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBF0891632.1"
                     /translation="MEYIKLNELCYINIGKTPSRNTSDYWGSGNRWLSISDLKEKYIS
                     KSKEEITDLAVEKANMKLVPKNTVVMSFKLSIGRVAILKEDMFTNEAIANFQIKNNEL
                     ITSEYLYYALRTLNFNNTDRAVMGATLNKSKLNDIKIPYFTICIQNKMVEVLNKAQEL
                     INKRKEQIEALDELVKSRFIEMFGEPINNTKKFDMKKIKEISIYLKRGVSPKYVEQSN
                     IKVINQKCIYWRNLKVENCKYYDENLKEKIEDIFLKQNDILINSTGTGTLGRCVKFNK
                     IDNSEYIADSHVTVLRSISNNLNSDYFAALFEFTNIQDTIYRKCVNGSTNQIELSVSK
                     LGEYLIMVPPIEFQNQFSEFVKQVDKLKLKIETNLKELEDNFNSLMQKAFKGELFN"
     gene            complement(44466..45929)
                     /locus_tag="KNP54_000704"
     CDS             complement(44466..45929)
                     /locus_tag="KNP54_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBF0891633.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIAVGLEELERMLEV"
     gene            complement(46439..47308)
                     /gene="gatY"
                     /locus_tag="KNP54_000705"
     CDS             complement(46439..47308)
                     /gene="gatY"
                     /locus_tag="KNP54_000705"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBF0891634.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(47328..49244)
                     /locus_tag="KNP54_000706"
     CDS             complement(47328..49244)
                     /locus_tag="KNP54_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBF0891635.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVAKLNNEEIKSV"
     gene            complement(49247..50167)
                     /locus_tag="KNP54_000707"
     CDS             complement(49247..50167)
                     /locus_tag="KNP54_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBF0891636.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(50269..51021)
                     /locus_tag="KNP54_000708"
     CDS             complement(50269..51021)
                     /locus_tag="KNP54_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0891637.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(51413..52858)
                     /locus_tag="KNP54_000709"
     CDS             complement(51413..52858)
                     /locus_tag="KNP54_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBF0891638.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            complement(52880..53233)
                     /locus_tag="KNP54_000710"
     CDS             complement(52880..53233)
                     /locus_tag="KNP54_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBF0891639.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(53262..54509)
                     /locus_tag="KNP54_000711"
     CDS             complement(53262..54509)
                     /locus_tag="KNP54_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0891640.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMETMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(54517..54834)
                     /locus_tag="KNP54_000712"
     CDS             complement(54517..54834)
                     /locus_tag="KNP54_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891641.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            55076..56989
                     /locus_tag="KNP54_000713"
     CDS             55076..56989
                     /locus_tag="KNP54_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0891642.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGAFILSSKKGYKVNLNTNCQTKIDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLVGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(57112..58266)
                     /locus_tag="KNP54_000714"
     CDS             complement(57112..58266)
                     /locus_tag="KNP54_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBF0891643.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEKLDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLDSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(58545..61160)
                     /gene="mngB"
                     /locus_tag="KNP54_000715"
     CDS             complement(58545..61160)
                     /gene="mngB"
                     /locus_tag="KNP54_000715"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBF0891644.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPDRKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLIAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEDWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(61304..63229)
                     /gene="mngA"
                     /locus_tag="KNP54_000716"
     CDS             complement(61304..63229)
                     /gene="mngA"
                     /locus_tag="KNP54_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBF0891645.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(63359..64084)
                     /locus_tag="KNP54_000717"
     CDS             complement(63359..64084)
                     /locus_tag="KNP54_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0891646.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(64347..65126)
                     /locus_tag="KNP54_000718"
     CDS             complement(64347..65126)
                     /locus_tag="KNP54_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBF0891647.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(65119..66546)
                     /locus_tag="KNP54_000719"
     CDS             complement(65119..66546)
                     /locus_tag="KNP54_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBF0891648.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            66937..67659
                     /locus_tag="KNP54_000720"
     CDS             66937..67659
                     /locus_tag="KNP54_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0891649.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            67856..69523
                     /locus_tag="KNP54_000721"
     CDS             67856..69523
                     /locus_tag="KNP54_000721"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBF0891650.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(69619..70938)
                     /locus_tag="KNP54_000722"
     CDS             complement(69619..70938)
                     /locus_tag="KNP54_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBF0891651.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(70979..71725)
                     /locus_tag="KNP54_000723"
     CDS             complement(70979..71725)
                     /locus_tag="KNP54_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBF0891652.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(71969..73978)
                     /locus_tag="KNP54_000724"
     CDS             complement(71969..73978)
                     /locus_tag="KNP54_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0891653.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(74416..75849)
                     /locus_tag="KNP54_000725"
     CDS             complement(74416..75849)
                     /locus_tag="KNP54_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBF0891654.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(75936..77852)
                     /locus_tag="KNP54_000726"
     CDS             complement(75936..77852)
                     /locus_tag="KNP54_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0891655.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQILITFDIESISKEGYCLETPVVVTNYSDYVDILENTQ
                     KHVNNSQELITVLA"
     gene            complement(77926..78786)
                     /locus_tag="KNP54_000727"
     CDS             complement(77926..78786)
                     /locus_tag="KNP54_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0891656.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(79137..80324)
                     /locus_tag="KNP54_000728"
     CDS             complement(79137..80324)
                     /locus_tag="KNP54_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0891657.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(80338..81729)
                     /locus_tag="KNP54_000729"
     CDS             complement(80338..81729)
                     /locus_tag="KNP54_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBF0891658.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VIAFLTIGLYLGF"
     gene            complement(82324..84024)
                     /locus_tag="KNP54_000730"
     CDS             complement(82324..84024)
                     /locus_tag="KNP54_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBF0891659.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(83996..85399)
                     /locus_tag="KNP54_000731"
     CDS             complement(83996..85399)
                     /locus_tag="KNP54_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0891660.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGMYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(85663..86154)
                     /locus_tag="KNP54_000732"
     CDS             complement(85663..86154)
                     /locus_tag="KNP54_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0891661.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(86180..86992)
                     /locus_tag="KNP54_000733"
     CDS             complement(86180..86992)
                     /locus_tag="KNP54_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBF0891662.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(87005..87964)
                     /locus_tag="KNP54_000734"
                     /pseudo
     CDS             complement(87005..87964)
                     /locus_tag="KNP54_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(88082..>89074)
                     /locus_tag="KNP54_000735"
     CDS             complement(88082..>89074)
                     /locus_tag="KNP54_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBF0891663.1"
                     /translation="VYKNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLD
                     NAYKKFFKEKAGFPKFKSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVP
                     QGRILNATISKEPSGRYYVSLCCTDVDIEAFENTNNHIGLDLGIKEFCISSCGEFIEN
                     PKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLI
                     KENDIICIEDLQVKNMIKNRKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFAS
                     SQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT        28801 a        16013 c         9471 g        34789 t
ORIGIN      
        1 ttataaacac caatatattt ctattatttc aataagtata caattagatt agaatctaac
       61 gctagtaata aaaaattact ttcccaaaat agatataagc ctcattttat cgttcaaata
      121 atgaaaatat atttgatttc atgcaaaaag agtgcctaat gaactaaaaa gttcattttg
      181 agacactcat ttttttatat aaatttatat agtttttaat cgttcgcatt caaccactca
      241 gttaagactt ttatatattt ctcattttct tcaacgaatg gcatatgtct tgaatactca
      301 aataattccc acttactatt aggtattcta tcatacatag tctttgcaat atatggtgaa
      361 cataaatcta ttgctccact agttactaga caaggctctt ttatttcatg taatctatct
      421 gtaaattcat atccagaaag agttcctgta ggagaaaatt cattttgtcc ccatcctaca
      481 atatatgctt cagaacctga ttttttaggt cttctcaggc actctggaga atcttctgtc
      541 acttcacctg cacaatacat ttccataaat ctttctaatg catcattata ttctttgcta
      601 gagtaatctc cagtatttac tgcatcaagt aatgcttttt ggtcaacctc actcatatat
      661 gatattcttc ttttttgttc tttctcccaa agttttgcag aagaaagagt agatgaaagg
      721 atgtaagact taataccttt tggtttatat tcaatagcat accaaatagc ctgcatacct
      781 ccccaagatt gacctaacag atgaatttca tcaagtccta gatgttttct tagttcaata
      841 agctcctcta tccaagtatc tgcattaaat agctcaggat gcccttctac aaatgaattt
      901 ccacaaccaa tttggtcata cattattact tgtctaccac tttcagctat cttatccaat
      961 acctcaaaat agttgtgtgt agaacctgga cctccatgaa gtaatactaa tggcttcttc
     1021 ccttccgtat tttctcctac tatacggtaa tacgttttaa aacctttaaa aggcatatat
     1081 ccttcagtaa ttttcatgtt tatctcctcc aatttgtaat tataaacaat aatcaagttc
     1141 attaacaata ctatttaaaa cctcttatac atatttgatt atgtatttta atctttatac
     1201 ctacttttat aaatagtata acataaaagt taaaaatctc tatactaaac caattataaa
     1261 attatattaa ctatataatt ttatttttta ataatagtat atacatattt gattattttc
     1321 atttgctatt taaaatcaat tttaagtttt cttcttataa taaacttcct ctttgtggtc
     1381 tcatgttagt ctctaaattt aaaattttac aaaaaatttt cataaaataa aattatattg
     1441 attgtatcta aacaaatagg gcaataaaat aattaagtat agttacttac ctttcaagca
     1501 atattagttt tatgttagaa ttttattata ttgatttaca ggaggtttgc atttgaataa
     1561 tattaattca cttaaagtaa taaaattatc tcttggatgt tctcttgcta tatttattgc
     1621 ttggctatta aaattagaat attcaatggt tgctggagtt atagtactac ttacagtaaa
     1681 ggacactaaa agagaaactc ttaaaggctc cattggaaag atttatggtt ttcttttatg
     1741 tactattttt tcatatttat gttttaatat tttaggatat aatttgactt cattttcaat
     1801 atttatattt ataattatac cactttgttt tttgttaaat attcaagatg ttattgctat
     1861 gtgtgtagtc atagcatccc attactacct tcaaggagaa acttctatca aatggatttt
     1921 aaatgaagct ggaatatttg cagtaggaac tggaataggt gtcttaataa atatgtatat
     1981 tccaacaaat atacataaaa tccatgaagt tcaaaaaaag ttacaggaag aagtgagtat
     2041 tgtacttata gacattgcag atattattgt aaatcctaaa aaagaaaatg gatatagtag
     2101 agatttatat acattaaatt cacttattga cagcagtatt tctgaaactt acgataatat
     2161 taataatact ttattaagtg atactagatt cttcttagag catatggata ttataaaaag
     2221 tcaacgggat atcttagaaa atttgtatag ttatgtatct caactaaatt ctacaccacc
     2281 acaagctcat attctatctg cttttataca taagataggt tatactgaat ttgaagctga
     2341 aacaggcaat cttcttcttg aagaattaaa gagactaatg cttagtatga aaaaccagcc
     2401 tctacctgtt gacagaacag agtttgaaaa tagagctatt ttattcctat gcttgactga
     2461 gttaaaacag tttttagtta atcgtaaaca tgctcagatg cttagagata ataattttta
     2521 taaataaaaa ggggagaaat ctagcagttg acctgactac aaaatatcag atataatatt
     2581 aaatgcgccc ctagtaagag ggcgcaatgt ttataactta ttctactgtc atgattaaat
     2641 cattattcat atcgaacata cattatttga ccaagtccaa tattagcttt ttcatcagtg
     2701 atttctattt taatagtcac atcatttttt ttacagtact tcgctaattc tgcaccagaa
     2761 cgatttttac cactaaaatc taaagaaaat ggcttatcat atttaaaagg atattcaaca
     2821 ggtttaccct ctggtgctaa tgcaaacatc ccatatggtg tgttcataaa tcctattaca
     2881 gcaatcgtaa gatttgatgg gtctaaattt gattcactac ctgtaaatgt aattgtattt
     2941 actgatgaat taactacact acatcgaaca ccttcataca ttacatgttt ttcatttata
     3001 tcttctcctt ttttcccaaa atttccaaca gcctttgccc cttcttgatg tggtaacata
     3061 gtgtgcttcc caggtggtgc tggtttctgt gtctgttctg gttttaccgt ctgtactatt
     3121 gcaccaactt ttggatatgc tgtcttatca aatggtaatg ggtggctaag actcttgtat
     3181 atgatatcct ttcctgctga tttattagca tcaatatcta catgatacaa acgcccatca
     3241 ccaaaacgga taagattcca ctggtggtca tttgatgtgc tgtgtacata ataagattca
     3301 attcccatag catcacacaa agctttcatg ctcctagcca ttcctgagca tgcacctttt
     3361 ttagtaacca atgtataggc agtatttgct ccctctactg cattccagtc aacatatgtt
     3421 gtgttatttt taatgtgatt gtaggcaact aaaatcttag catctgtggt catattcttt
     3481 gtgattttct tgttcataaa atctgctgtt gcttgtgcta ctgagtttag ttgggcttgt
     3541 gacagctttg gaccatatac gctattggtt ccagtgacat agctttttgg tgtttttgct
     3601 gttacctctt tggctgtcat accataaact gtcatactca tacctgagat taaaactatt
     3661 gttgtaatca ataacttggt agctaacttc ctaattttct tcatacttaa tattctcctt
     3721 tataaaacat tgttacttcc tattctctac cattaataaa attaatttag gatttaaaaa
     3781 ggtggattgt caacatgtat atttctccat tcatacattc gtgaaatatt taaatttcat
     3841 ggaaaatcta atagatattt tctagataat ttgtatacaa tacaactcgc aaatcagggt
     3901 gtttgctgtt agtttgagaa aatgatgatg attaatacat tcggaatctt tgacctataa
     3961 taaataccat tgtcttcaat cattaataat ggtaagagta aagagaatta tcaataatac
     4021 agttaaaatc aactttgtat acatttcata cattctctcc caacaacatt atacttctta
     4081 taatttgtat attcaatacg ttttctggga aaatatagga tatatctata aaaatataaa
     4141 aaaggagttg aacttaaaat ttgattaaaa aaaatcaatt ttaagacaac tcatttgtat
     4201 tataaaaatg ctatatatta ttattaagta agtcaatatt ttagatattt atctatttct
     4261 tattgactta cgcttatagt ctaacttatt tgtttagttg atatataacc tagttttaag
     4321 cattattaat atttaaataa tcaagtatcc tttttgtttc ttgtagtttc tgttctgcct
     4381 catttaagtt ttcttgaatt atagaaatat atattatatc tatcaacgta agcattgcta
     4441 ttcttgaaga aatagctcct tctctaagcc ttttttctat atttggtact actagtttta
     4501 aatcactaat cttactaaga tgattgtcac tatatttagt tatacaaatg accttacatc
     4561 cttttaattt tgcattttct atagacttta ttacttcttt tgattctcca gagtaagata
     4621 ttgctatagc tatatcttct ttatctacat ttgaagatac cataagttgt gtatgactat
     4681 ctaaagaggt aaatgcctgt ttatttatcc ttaaaagttt catctgtaaa tctagtgcaa
     4741 ctaaagccga accacctact ccaaatatat atacattttt agcctttatt atctgttcaa
     4801 ctgcttcttt tattatatct ttttcattca acaaccttgt ttggttgata gtctctatgt
     4861 ttttgtttgt aattttgttt ataacactat ctatattaca atcatagttt tcatctacat
     4921 atgtgtattc attttctttg cccatcaaat ctttagctat ctcaattttt aaatccccaa
     4981 aacccgaata tcccattttt ctagaaaacc taactatact tgctgtactt gtttttgagt
     5041 ttgacgccaa ttctgataca gaaagcttac ttatagcctc tgtattatta agtatgtaat
     5101 cagctatttt tttatctact tccgttaaat cttcatatat ctgttttaat tttaaaatgc
     5161 aactcatact ctatcacctc tacctattta ctataatatt tcttcttagc aagtaaacat
     5221 gctcctaaat ctggagtcaa cactggtctc actataccaa atctcgtttt attcaaatat
     5281 tttttaagtg gctctaatat taaatctcct gacttaaaca ctccacctga ataagatacc
     5341 tttatctttg taccttgttc aaaatgatgc tctaatccta ttataagcct acttaattca
     5401 taagctgcat catcaaatat tttactagca gtattatcac cttcaataac tgcttttaaa
     5461 catatcgtag caaactttgc tatttctatt ctatctcctt ttatttcatc atttacatat
     5521 tttattatgt cataatcatt ctctatatta agatgtcttt ttattaaatc atataatttt
     5581 gtttttgaac accttccatc agactgcatt gtgaacattt ttaaggtagc cattcctata
     5641 taatacgctg aaccttcatc tcctaataca tagccccatc ctccacatct gtgaagattc
     5701 ccatctttat ctaaagcctg tgctattgaa ccagtacctg caattatatt tatacctttt
     5761 tccccattta aagaacctgc taatgctatt tctacatcat tacctagagt ataatttata
     5821 tgactatatg cattttttgt tgctacttct aatgcataca atacttcttt tatttttcca
     5881 tatccagcaa gtccaacaaa tgcatacgtt atttcttcta catttatctt agcatcttta
     5941 caaacttctt ccaacccagt tattaataat ttcgttagat tatcaaatcc tatttgatta
     6001 taatgacaag ttcctttggt tatggttcct actatattta attcttcatc tactaatgta
     6061 aatgttgttt tcgttcctcc accatctaca cctaaaaaat acatactatc ctcctacaat
     6121 atctttaata attctttcaa tacttaatat ctaaaaataa ccttccaatg ctgttttttt
     6181 aatattgaaa ggttatcagt actattattt attttacaat ttttctattg attttaaagc
     6241 ttcacttata taaccttctt gtctatctag gatactcttt gcactatcct tatctaaacc
     6301 actttttatc ataaatatag ccaatttaac gctattatct gcttcttcta agaatttttc
     6361 tgcaacatca tattttacat ttgtagctat cattattatt ctttttgctc tttcaaccaa
     6421 cttttcattt gatgtcttaa catctaccat caagtttgag tatacttttc ccatcttaac
     6481 catagaagct gttgttaaca tattacatac cattttttga gctgtaccac ttttcattct
     6541 agttgaaccc attattactt ctgcccctac tataatgttt attggtaaat ccgctttttt
     6601 actcatttca ctattcggat tcatagttat tgatagtact gcacacccca attccttagc
     6661 atactccatt gcacctataa cataaggagt ccttcctgat gcagctatac cacatataac
     6721 atccttagat gtaactcctc tatctattat atcttgcttt ccaagttctt tatcatcttc
     6781 agcaccttct attgctttaa atattgcttg atttccacca gctattatag cttgaacaag
     6841 ctcaaaatcc actccgtaag ttggaggaca ttctgtggca tctagtattc ctatcctccc
     6901 actggtacct gctcctatat agaataatct acctccctgt ttcattctat ctactattat
     6961 attaacagct tttgctatac tctccttttg ttcttcaaca gcataggcta cagttttatc
     7021 ttcgttattt attaattcta ttatgcctaa tgtatcttct ttatctattt gcaatgtatt
     7081 cttatttcta ccttctgtaa ctaaattttc taaagttttt attaacatat catttcctca
     7141 ttttcttaat attaaatttt taaacacatt ttaattccaa ctttcataat tatattttta
     7201 taataaatta atattttcat aataaattat tttgttgagg gtttaaaatt aaacttttgc
     7261 catggtttaa tataatctaa tataaataat tcttcttttc ttatatatcc tactacattc
     7321 gatttaccac tgtttttcat atcagtcaag gctatttgta actcccctgc ataatgacca
     7381 tattcactac tttcaattac tatatctcct ctttttatta ttttaggagt attaaatagt
     7441 tcaaatttat atcctttata tttaacacga gattgagtag accttatcag actatcagat
     7501 atgtcccctc tattaaaatg tatttcttca aagagtatct tcttctcaac ttctcgtata
     7561 ttttcctcta ttgctacatc aaatgtaacc atatcttttc tcatagaacc taataccttt
     7621 agctcctcat atgttggata acaatttgat attattatat catttatatt attcatagct
     7681 attatatgct ttacttgaat atctataggt agatttctgt gcatctcaat tgttggaagc
     7741 ccatcagtta caggccatgg tccaaatgta gtttcatttt gacttgttac aaaaactgct
     7801 gttcttaatc catacttatt aaatctttct gtacatttta taaagtgttc taaatttaat
     7861 ccactatatc tatgtggata aaagttatga catcctatca aattttcttt atttggttgg
     7921 tagtccatta ttgtatctat ataattagta ttattactca tattgatttc tattttaaga
     7981 ttttgaggat taaaagtcat taatgcctct tcagaacctg taaatcccat atcaagcctt
     8041 attccgtctg ccttcgtctt tttaaaaaaa ttcaaatctt tgtagcttat ttctaattca
     8101 ccaaatactc tgggatttac atcaagtatt acctcaaaac ctttaaactt agcgtattca
     8161 tttatacttt taaatttttt aattatattt tctttagtat ctttaactga taataaacat
     8221 gaaaatatac gtgtaaatcc attttcagca gctttatcta tataatcata tatttcctta
     8281 gatgttgttt tttctggata aattgatatt cctaatcttc ccatctgtgt catctcctta
     8341 tatcctatat gtgtttaaat ttatttcgaa ttacacgaaa cttttttaaa aatttgatga
     8401 aaaaaagttt catatatatt tataaaaaaa gaaaagttta ccttttcttt ttttataaac
     8461 aatcaacaaa atatcttcgt tacttatttc ataactgtta tactttgaaa tttatactaa
     8521 tctaatatag tttttaattt ccaatatagt ttctaattaa taagcttctt gctcttcaac
     8581 tttttcttca tgaagcaacc tcttatcgta catcttgaca aatggatagt aaattattat
     8641 tgatatagct atacataata agttaagaac tgaagctctc caatctccac cagtggctaa
     8701 atatgcccct actggtcctg gtaatgtcca aggagcagta actactactc tggatactaa
     8761 attagcactc atagcaaacc atgaaactgt tgccattact attggtgcta caacaaatgg
     8821 tattattaat attgggttta atactattgg cgctccaaat attattggtt catttatatt
     8881 gaatattgct ggtattacag ttgcttttcc taaagacttt ccataagctg attttgctct
     8941 aaatgcaaga agtaaagcta agcctattgt agctccagaa cctccaatcc atataaacca
     9001 ttgaaaaaag ggttcagcag caatacctgg aactgcttga cccgcagcat atgaagctgt
     9061 attagcatct aataattgta tccataaagg tcttgccaat gaacctatta ttgatacacc
     9121 atgtattcca aatgaccaaa aaaacgttat taaaaatatt agtataatta ctgatggtaa
     9181 tgtgtcagtg gctgaaacta atggagttac taatttagct atgaagccat gccaatcaaa
     9241 ccctaggaaa taagtaacaa tagccattaa aattattatt aatgcggctg gtgtcagagc
     9301 ttcaaaagac cttgtgactg atgctggaac tgcttctggc atggttatct tgaatttaga
     9361 tttgtcagta aatctataaa tctcaacacc tattatagat gttacaatag caacaaacat
     9421 tgaacctcca ccaagattag ccattggcat ttgccatcct tgaggaattg aattatacca
     9481 agctaaaagt tctggactct tttcaactat ctttaataaa tcaggggtaa gaccctctat
     9541 tgcagtagga actattgtca aaaggaatgt agctgtagct aataaacctc ctgtcaatcc
     9601 atctaactta tatgactttg ccaaactata acctatgcca aatgtagaat atactgatat
     9661 aataaaaaat gtcattctat atggtagtaa tattgtaact gcattttcct ttagatactg
     9721 agttaccccc catgaatctg gtaatggagg aaatgctaat atcaagaaaa atgacccaac
     9781 tattataagt ggtaatgaag ctacgattcc atctcttaca gctcttaagt gacgttgttc
     9841 tgccaatctg gccatagaag ttgataattt agtgtctaaa aattctgtaa atttatctag
     9901 catcttttct ctccttaatt aatatttatt tttattatca ttaaaatttt tataaaatta
     9961 actttcttct aatctaacaa cactgcaact actatttact caacagctct tgaacttgtt
    10021 ttaataactt tggtcctcct aatggactat aagcttgtgc ttgtattaat gcacatggta
    10081 cactaacctc atcagcaaaa gcttttaaat agtcaaatct atgtctaact tgtggagcta
    10141 ccatagcaat atcccatcca tttttaactt catcctcaaa ctcttgagta ccaacagcca
    10201 aaacatctat atctattcca ttttttgctc cttctttttg taatgcatta actgctatag
    10261 cacttgacat ccctgatgaa caaacaaata atactctcat attgattccc cctgtttttt
    10321 tatttctttt caatcattat agcatgtatt tttgattaca ggaatacgtt tgtatatatt
    10381 tttttcatat tttacatttt aaattgtaat tttatttcat acatttatat cttgctttaa
    10441 ttgctttatt tatctaatca ttcttttgtc taaaattaca cactacttaa aatactcata
    10501 tcttttctta aaaaagaaaa aagactatct tattattaac ataaaatagt ctcaatactt
    10561 ttttaaatat gtattccttt atatatccag aagtaaccta ttattgcaaa tgataaagca
    10621 aataaaatat acagtctaaa aaatcccaaa gaaaaacctc tcttagtttc aacaaagtat
    10681 cttgtatatg caactgcaaa agatgtaatt aatgaatttc ctataacaac tccaaatcta
    10741 ttatctattc caaatataga taataacaaa ggaaaaacta cagtacttac tagagatgaa
    10801 actattaata ttaatccact tttaaaactt atagttggaa tattataatc tgttctttga
    10861 tttttctcca tttgtttctt agtattttta ttactttttg tactttttgc atttttataa
    10921 ttattatttt tctttctttt ctttttttta ttattagaca tgtcatttac ctccaaaagg
    10981 tttaggtgtt atattcccta aaataacttt atttttagcc cctgttgcag atattacatt
    11041 agaaaaagaa ttatttaatg tttcattgcc caagattaca aatgccaaag cctcctttgc
    11101 atcagaagaa tacccatatt catcttgagt taatacttca acctctaata ataactcttt
    11161 tatatatcct attaaagtta gattatgagc tcctccacct ccaattaata aagtatctac
    11221 attaaccttt ggaagtatga agtttttata attataatat atagcttttg ccgtaaacat
    11281 agttactgtt gctatcaaat catatttatc tacatgttta tatttgttaa gcatgttatc
    11341 caaataaact tgtccaaata cctctcttcc agtgctttta ggtggcgctt gactaagata
    11401 cttatgactc atcaaatctt ttaacatttc ttcattaatt ttaccttttg atgcaaagta
    11461 tccattttta tcatactttc tattaaataa tctttgacat actccatcta ttatcatatt
    11521 tcctggtcct gtatcaaatg caaatacatc atctatgtta catgatttag gtattatagt
    11581 aatatttcct attccaccaa tattttgaag tgctaaattt ttattgttat cactatataa
    11641 taaaaattca ctatatggta ctaatggagc accttctcca cctgctgcta tatccattac
    11701 tctaaaatta gatattacct ttgtatttgt ttcatatgct ataactgctg gttcacctat
    11761 ttgaagcgtt gaagatacaa aattattata acttcttggt atatgaaaga ttgtttgacc
    11821 atgagatgcg ataaaatcca aatttgctat atgaaagttt gctttatgac acactgattt
    11881 tacagcttta ctaaataaat atccaagctt aaaatttaag ctacagatta aatcaacact
    11941 cgattcctct tctatacagc actttcttat ttcgtctttt atatctttag gaatttctag
    12001 agttataaat tctatttgct taactttagt atttctacca ttcccactaa tttcagctag
    12061 tactgcatca actccatcta aggaagttcc tgacattaaa cctacactat acatagttat
    12121 catcctttta agtttatagt tattcctccc caaatcaagg tattaagttt aataatttta
    12181 gaattaatct tatttcatct ttaattacga taatttactc ttatgaaatt aattgagtta
    12241 atcttataca cgttttttac cttagctaaa tcttacatta atttattttc agtgtcaatg
    12301 taataccatg taattttttt tcacaaacaa aacatattct ctctccaaaa accatattaa
    12361 aatagttact acaaataaaa aacataccag gtacctatct gatatgtttt tcatatataa
    12421 taattattat tttataatat agatagagca tcatttaagg cactaattaa atcttcacta
    12481 ttttcaagaa ctaaatttat tcttattgta tatgtcgatt tgtatatgat gatagatttt
    12541 atagtctaat aacctaacta tctaggctta aataatccga tatatcataa aaatagatat
    12601 taaaaattgt atatgaacca ttttccgaac atacctcaat ctcatgccct aaactatcta
    12661 tcattttctt tacaaaatac atccccattc cagtagactt atacaattga tttcttccat
    12721 ttttccccgt aaatcccttg tcaaaaaccc tagatatatc ttcctcattt atacctatac
    12781 caaaatcttt tatagataat accactccat tttctaactt ttttgaatta aattcaatct
    12841 taccaacttc ctttgaatac tttatagcat tattaataat ttggtctaaa acatatgaca
    12901 tgcatttaga atctgtgtaa acatcatttt ctaattcatt caaactaact tctacattat
    12961 tttttataag caaaaatgaa ttatttttta tagacatttt tatcaatttt tctaaattaa
    13021 atttatttat aaatacatct tcaaacatag tgttgcttct actactatac aaaatagagt
    13081 ttactaaaaa atttatcttt gcaacctgat tcttaatatc caaactatct tctatgctac
    13141 ttaacctatc tgtaattata cttaaagaag atattggaat ttttatttca tgaacccatt
    13201 tagctatgta ctcatccaat tcttttaatg attgtttata agtctctatg tcactattat
    13261 tttttatttt taagttttct ataatatctt ttattagatt ttcttcaaaa gattgtccat
    13321 caactaaata actgtctatt tcaccactat tttctataca attatataaa tttgtgtaac
    13381 tatttctaaa atttatataa tctataacaa aaaataccat tattataaac agtactaaaa
    13441 aatctaaata tattaactct gaatatttat ttttaaaaat atctatagca aataagtaga
    13501 tatttattat actaactaca actaaaggta gagcaatata cttagaccta cctttcaaat
    13561 attttactag cattgtatta tatatcctac ccccttctta gtttttataa aatcatcaaa
    13621 acctagttct ttaactttac ttctcaatct attcatattt acagtaagtg cattgtctgt
    13681 cacaaactca tcattatccc atagagtcat cataagactt tcccttgata caaccctatt
    13741 cttatttttt aataataatg ttaaaatttt tatttcgttt ttagtcaact ctatactttt
    13801 atccttatac ttatgtttta taatcccttt ccccacatca aacatcaaat cttcacaata
    13861 caaaatacta ttagaatcac tataattata gactcttctt attataccat ttattttggt
    13921 aaccaatatt tctatagaaa atggtttggt aatgtaatca tctgctccat tatttatacc
    13981 cattattaaa tccatatcag aatctcttga tgataaaaat attaatggta catttgaaat
    14041 agctcttatt ttttcgcacc agtaaaatcc attatataat ggtaaattta catctaaaag
    14101 tactacatct ggttttttat ctataaattc atctaatact acctcaaaat catcaattaa
    14161 ttctacttta aatccccatt tttcaagtgc taatgcaatc tcttttgata aatcaatatc
    14221 gtcctctact aataaaattc tatacatttg tatattctcc attatcctaa tatttcacta
    14281 tgctatgaat tattaatatc ataacatatt ttatatgaat ttattaccca aattatttag
    14341 ttaatcaaca aggagactct tattacaaga atctcctttc tctttattaa tatatcaact
    14401 aatttttata cactacactc ttaaacttat taacagatac tgctccatat attatgaata
    14461 ttatcaaaca tatcactaaa cttagtatat atataccaaa taaatcggtc atcaataaat
    14521 ctcctgctaa tctcaatgca aaataactag atatagttgc acttaacatt ggcaaagtat
    14581 aaaacatagc tacttcttta agtatagctc tatttatatc tttttctgta gtacctattt
    14641 ttaacaaaat cttatatttc tctttatctt catatgcatc actatatatt ttcatatata
    14701 ttatacttcc agctacaatt gcaaagacta agaataaaaa cacaagcact acatatgcaa
    14761 acttcatcca ttgactctca ccttgagctt tatatccatt ttgaatatac ccatttttta
    14821 aacttaaatt cttttcaata ttgttgaaca ttacttgact attttcttct tgaaatacct
    14881 ttgcaccata aaaatacact tgttgaccct tatctcttag tttaaaatat gtatcatcat
    14941 ttaccactat aatactttga ttaagtcctg tccctagtac tggaactttt acttctcccc
    15001 ttgaaatatt atataactga ccatcaagtt ttatcttggc ttcttttgta gctattgatg
    15061 ctatcgtttg agggcttttt aactctatta cattatttcc actaactaat ctttcaccat
    15121 actcttttaa ttctttatca ttgccattca ctttaagagt attacaaaaa tcactatatt
    15181 tcattatagt atctgttgta tcataagctt cttttatatc tgttttcttt aaaattgtta
    15241 gttctggatt tactgagtac tttatcttat tagtatcttt tattatattc tctatttgtt
    15301 ttttattcac ttcatcttta tccattgaaa ctatgctaat agtgtacaca tttctttgtt
    15361 cttgggcatt cttatgtata cgcttcatcg caactgaagc accaagagtt gatattgttg
    15421 tagttataat tatagctatt atagcataag ttttatagtt tttatttaat cggtagttta
    15481 tattgtttat tgcaattata ttatttccat taaataatat ttttttattt ttgattataa
    15541 tatcaaatat aacaggcata actgatttga ataatccata agtacctact attattatac
    15601 ctataacagg tagtacacta gttatatctc cagttcttat attggtagaa agatagtagc
    15661 catatcctat tactataatt gatactatag ctaatatata tatacctatt cctacctttg
    15721 gtattttttc ttgtttttta gatatattga ttagatttat tacactactt ctacatattg
    15781 ttataaaacc ttttacagcc attattataa atatagaaat aaagattaaa gtagcatata
    15841 gtatagcttc tatactaagt ccattagata cctttatatt aaatccagat aactttatta
    15901 tcactacttg aaaaaatcta gatgttatta tccctataat tattcctgtt atacaagaac
    15961 ttattcctat aagcatattt tctacaaaat atatttttcc tatagtatat aaatctaatc
    16021 ccataaaaga caatattcca atttctttag acctattctt aaaaaatata tttgttgcat
    16081 accatataaa gaaaaataaa aatactgata gtatcattat tacagctact aacactgata
    16141 gtgtaaattt tttattttca tcttgtaaca catttatagc atcaccatat cttaataatt
    16201 caaaattagt tagcacaact actgaaaaaa ccatagatat aaaaaatgct agataagttc
    16261 ttatgttact cttaaaatta ttataagcaa ttccaagtat actcacttac atctcacctc
    16321 ccatagaggc tagcatatcc ataatttttc cataaaattc ttttctacta tttcctttgt
    16381 ttaatttaca ctttatattt ccatcattta tcatatatac ttcatttgaa taacttgctg
    16441 ttagagggtc atgtgtaatc attataatag tagcgttatt ttctctgttt attttttcta
    16501 atgattctaa aagttcatat gctgatttag agtctaaagc accagttggc tcatcagcaa
    16561 atatgactgt tggatttgta attaatgacc tagctgctgc gcctctttgt ttttgtcctc
    16621 ctgataactg atatggatat ttatctaaat gattttctaa tccaaatttt ttagctatag
    16681 aaaatacctt agcttctatc tccttacttt tcttttttcc taatgctaga ggaagtgcta
    16741 tattgtccat tagtttcata ttgtctaata gattatagtc ttgaaatata aaccctattt
    16801 tttctcttct taattttgat agttcattat tttttacttt tgatatatta attccatcta
    16861 gtattatttc tcctgaagtt tgtttgtcaa gtgtagacat taaatttagc aatgttgtct
    16921 ttcctgcacc agatggaccc attattgata taaaatcacc ttcattgact gtaagagata
    16981 tattttttaa cacatttgtt ttaaatcctt ttattccata atcttttgat atatttttta
    17041 tttttaatat ttctttcata ataatagcct ccagttgcta attttttaat atatatttat
    17101 tttaaaggtt ttatataaat aaatccttaa gtaaatatta cattttaact gttagcatta
    17161 cacttttgta acatatggaa gactattata attatagtag aaatatctta aaataaaagc
    17221 atgatttact tctttgtata aacaaagaaa agaagctcct aagaagcctc taatctatac
    17281 aattattctt ctctataaaa aaccaaaata cacattgatt gtggcaaata cagatactat
    17341 aaacaagtga tattactact atatattaaa acaattattc ctgaagataa ttcaataaga
    17401 ctatcaagca ataagctaag catccaaaaa gacttaatac cattaatgta taattatacc
    17461 caatattaat gctcaaaaaa ccagcaacag ttggaataat cagagatgaa cctcccataa
    17521 atatacttaa agctattaat tggctactac ttctaagttt tttaggagaa acttcaaata
    17581 ttaatctttt tgaagtaatt aaaattaaag gagtagaaaa cacttgaaaa acacacagta
    17641 taataatgat atttgaatca tttgttaaag caaataatag aaactgaact gttatcataa
    17701 tagcacttaa ttttaataag tttaaactgc tatatttttt taataaataa gaaccagcca
    17761 gatatgttgg tatctctaac aatgactgta aagaccactt taaagatatc tgagaatttg
    17821 tagcatttaa agctatcatt ttatctatta cagtacagtt atttgctacc accattgagt
    17881 ataataagaa taaaatacat actagtaaga tatatttttt atcttttaat aattcaataa
    17941 tatctttatt agttacattt attttcttat taatcttttc aatatcaggt aataatagta
    18001 tatttataat aagtaatact acaattaaac caatcgctac agataatcca aaatatgaga
    18061 atctaagaat caagtaagat gctaccatac ttccaatagc ccatccaatc gacccaaaag
    18121 tcttaataaa tgacaaataa ttattaatat tatctccaca acctattatc catgtatcat
    18181 ataaactaca gcaagtattt aataatcctc ctgataaagc aacaagtaat aagtatatta
    18241 taaaagttgc agattcagta gaaaacataa taactgatgc aattccataa actgataaac
    18301 taattaaaac aatttttttc attgtttgat acttatcagc taatactcca aataataatt
    18361 gaaacaatat attggttatt gcatagctcg ataatataat tcctctttca aacgctgagt
    18421 aacctaattt tgataagaaa ggtgtgaatt ttgttgaagc aaaggcaaaa ataatatatg
    18481 agaaaaaata gaatatgata aatttaaatt taatcgcttt attaatcata atcaatcaaa
    18541 attgataact ttaataccac tatttccttc ctgatttaag tttgaaagat gatattttac
    18601 cgtattagga ttctctacaa taactaaagg aatatataaa gtattttcaa gtaacttatt
    18661 atcaatttct actaactttt cccccatatt aacttcttga ccttgtttaa cttctaattt
    18721 aaagttttct ttttttgttg ttgcactatc caatccaata tgaataagaa tttgaacatc
    18781 attttgcaat ttaattccta tagcatggtt agtttgagca ataaaactta ttactccttt
    18841 agtcggtgat ttaagaatat tgtcctttgc tatcatagca aatccatctc ccattacctt
    18901 agttgaaaat actttatcag gaatttctcc aagattaatt atttttccat caatgtatga
    18961 attaattgta attgcttctt tttttctttt aaagaacatt atagacactc ctctacataa
    19021 ttaactttat tctaattatc attacaaata acgatattaa gcatactgca attgaggaaa
    19081 aaagagcctt atagctcttt ccccattgta gttctttaat actgcttatg atttgtttaa
    19141 ttccaacaaa tttataaata taggtaaaca tgataacaat agttattgtg taaatttgga
    19201 atatctgccc taataagact aaatagaaag caatcatgtt ttcttttatc tctttattct
    19261 tttttatatt gtaaataaca tatgcactgt atactgcact aaagttagag attaaattta
    19321 aacttgcatt aacatcattg tttaaaagtt gtgaaaatga aatatttgta aataatgatg
    19381 tcaattctaa atacactata tataaaacag gtaatattag aaaacaaacc ataaccactg
    19441 aaagaaatat attttcatct tttaatactg ctgtgatatt ttttatttta tttgttatca
    19501 tgtttttgtt ctccttattt aaaagttggc cagaaatcct tattagccac aatcatttca
    19561 tctaagattt cttttgctac ttttgcactt ggaacagttt tactcatagt aaacgactgc
    19621 cataattttt gataactttt ttctatccat gcttctacag ctaatttttc agaagcaact
    19681 tgttgttcca ttaaaccttt ttggaaagtt ggaattttac ctatagacat aggttcaacc
    19741 atatcttttc caacaaggca aggaatttca accattgcat catctgcaaa attttcaata
    19801 gctccattat taggaacaat cagtaaaaat ctttcctgag tattaaatgc taatgcacaa
    19861 gctaattcaa caataaattg agaatgttca cttgcatcaa accatgtatc tcttgctgtg
    19921 ccatttttta taattctttc acattcttcg aatgtatcct tttctcttct atccataatt
    19981 tcatttgctc ttgtataatt tggattagca tgttcaacag tttcatcagc cattaaataa
    20041 tattttaaat aagtattagg taatgtagtc ggttctattt ccaataaatc ctttgctgct
    20101 ctcatagttt ctaaccaact agattctttg tgttgacctt gaggtgtaaa ttcctcatat
    20161 ccttttttag cacaatattc ctgtaattta ggcattaaat catttccttc tttgtcctta
    20221 atacttgtcc accacccgaa atgattcaat ccataatatc taacatcaaa gtctttacga
    20281 gaatttaaac ctaaaactct agcaaatatt tcctctaaac atactggcat atcacaaata
    20341 ttaataattc ttgaatttgg tcttaataca cgacatgctt ctgcaactat agctgctgga
    20401 tttgaataat taagcatcca agcatttgga gaatattttt ccatataatc aatcatttcg
    20461 attattggac ctattgttct taatccatag gcaattccac ctgccccaca agtttcttga
    20521 ccaacaaccc catattttag tggaattttt tcatcttgtt cacgtaaagc atataaacca
    20581 acacgaattt gtgccattac aaaatcaata tcagtaaatg cttcttctgg atttgttgta
    20641 taactaaatt taatttctgg atttttctct ctaacaatta ttgcacatgc ttcagcaact
    20701 tttctttgtc tctcatcatt attatcatat aatttaattg attcaatagg aaatttagca
    20761 acactttcaa ttaacattgt tacaattcca gcagtataag tactaccccc accagcaatt
    20821 agtatcctct gtctttttct ttccatcttt ccttctcctt tataataaat tttcaaattc
    20881 ttctcttaca cttggtactg aaagcccaat aataatctga atagcttttc cattatgcac
    20941 taaaccatgt gcacctactg ccttaaaatc ttcttcttta gaaataattg agtcatcttt
    21001 caaggttaat ctcaacctcg tagcacagtt tgtaacatct acaacatttt ctgctccacc
    21061 aactaatttt atgtattcag atgcttgttg agaggcttta ctcaatttat ttcctttttc
    21121 atctttagtt tctaagtatt catttttagt atatagtttt gtttcttcac tatcttcctc
    21181 tctaccagga gttttcatat caaacttctt aattaagaaa gtaaatacaa agaaccagat
    21241 aaatgaaaat ataatcccta caacaacttg aacaacatat accttccagt gatacattcc
    21301 aagaggaagc caatttaata caacccagtt aataattcct ccaccaaaat caccaacaac
    21361 tcctagggca aacgaaatcg tttgcaagca tgcatctaaa aatgcatgta ctaggaataa
    21421 aagtggtgct acaaataaaa atgtaaattc taacggctca gtaattccag ttaatactgc
    21481 agtaagagta gcaggaatca ttaaacctaa tacttttttc tttttttctg gctttgcagt
    21541 tacatagaaa gcaccaaata cacctaatga accaaacacc ttcgataatc cggataatga
    21601 aaatccgatt ggatacattt cctttagagt cttagctgaa gtttgaaaat cctgaatatg
    21661 agtagcccaa tatactgatg taccacctgg aacaacaaca ctatcataac aaattggtgc
    21721 atatacaaaa tgatgtaatc cagttggtat taaaatcttt tgtaagaatg cataacacca
    21781 aactcctata tttccactat ttataaaaaa cgtttgcaaa tgtctaataa cattttgaat
    21841 atgaggccaa ataaaacaag ttaataatgc aactggtatc ataacaaaga aacaaattgc
    21901 aactacaagt gatgagcctc taaataatcc aataaaatct ggcagttctt tatcataaaa
    21961 tctattatga atataaatga caatacctga tattaacaaa gcaccaacca taccagtatc
    22021 taatgtttta ataccagcaa tgcttacaag tccacttcca gcacttattt cagctgcgaa
    22081 atcaactcca aagctttttc cccaaaaact taacatagaa cctacaaaat aattaaaagt
    22141 caaatacgtt gctaaagcct ccatacaagc tcttgcttgt tgcttttttg caagtgctat
    22201 tggtaaagaa atagcaaata ataatggcaa ttgattaaat accatccaag ctccactaga
    22261 tattacaccc caaaattggt accaaatatt ttctggtgta gcaagtgaac ccataattga
    22321 ctgattttga aatacaattg agaatccaac cattatccca gcaaaagcaa ataatagtgt
    22381 tggtgtaaac attgcccctc caaaacgctg tattttcttc atcatataaa ttactcccct
    22441 cctcatattt ttagtttatc tttggcctta gatatctatt attttaacag gttaataaat
    22501 atatacaatc tttagggtac attcggagct tattcacagt caaataagtt tttgcacatt
    22561 tttatgttca aattctcata aaaaaaaaga atgactacaa tttgcaatca atcccttctg
    22621 taatcattct atgcctttta taaatactat atttaataaa taataactca atcaatataa
    22681 aatataacat tgtcaattta taactagggt gcatttgtaa aaatgagata ttagtcgctg
    22741 aaatataaat tgattcatca cttaaatcag tcaatgtatt atttttaaac tctgtaattg
    22801 aaattatttt agttcctatt aattttaatc ttctagcaat attaagtgta ttctcattct
    22861 caccacttag ggatataata atcataacat catttttact gacaatattg taaaaagaat
    22921 catcaaatgt tcttccctca aaatcatata ttatttcttg acatgataag aacattctct
    22981 ttatctgttt tgcaaccaca ttttgaatat cacctgaacc ataagcgtat attgttcttg
    23041 attcataaag aagtttacac aatgcatcat aatctttatt tttttgatct tcaacatact
    23101 taattattga attacatgca atatcaaatg actgattttc tatgacatga accttttctg
    23161 attcccagct taataatact ttaaactcac tgaaaccttt taaatctaat tttttaacaa
    23221 atcttgtaat agttgcacga gacacattac atttcatagc aagttcattt attgacatct
    23281 tactacaatg ttttttattt gcagttatat atttccatat taataaatct gtatcattca
    23341 atttattata atttaaaaaa atcatttctt ctaatctcat aaactattac cccctttaat
    23401 taaaaatcgt cataaatatt ataccaatat tcaacattaa attacagcgt attcttatat
    23461 ttactattta gcccataaaa ttgactataa aaaatactgc tataattgat gtttaaaaaa
    23521 atgtagtttt aattttattc ttttatctaa taattaatat tttcaagttc tagtgctttt
    23581 cttatacaat tatcatcttt aaaatcagca gtccttttac aatcttttac tttaaattct
    23641 ggaatagttt taaattcctc atcacatatt ccattcttat ttaaatacat acaacttgcc
    23701 attctaacta ttagaccact attttttaaa ttaaacaata cagggtctat acaccctcca
    23761 tctccgccag tagtttcacc aactaaagtc gcaaatttat tttctttaca aaacattgca
    23821 aatgactctg atgatgaata tatttttcta tcaacaagta agtatatatt acccttaaat
    23881 tttgaatcat ctgtagattt tatagtatag gaagtatctt caaaatcatt aaaatctttt
    23941 ataatttctt taggtgcatt ttcctttaca cttgctggta aattttctac aggatttaat
    24001 tttatatttc ttgcatttgt atattttttt actatttcat tattatttct ataaattcta
    24061 taaccattta ttttgacatc attttttatg agtttagata cgattccctg ccaataccta
    24121 tcacttccac ctaaattacc tcttatatca ataattaaag ctttatgttt ttctaaagtg
    24181 ttaatataat ctccaattat ttttaaatca ttatttatag agccattctt tgatgacatt
    24241 gatggtaaat acatatatcc aatctgaccc ttaataacat cctttaaaat taattctttt
    24301 tttacaaaaa tatcatctgg catttttatt ttaagattca tagagtcata tctatccaca
    24361 acttttttat cattaagaaa atcataccaa tcattattag agtatgattt cttaaaaagt
    24421 tcatatcttt tcttattatc tattacttct gtgtgtttat tatttaaatc agataatata
    24481 gatgacagtt cttctataaa ttcttcatca ttttcagtgt tttttattcg ttttgtatat
    24541 tcatccttat ttgctaacca atcaatatta ttaagcctct tatttacacc tagatatgga
    24601 tatcctgtct ttacaacatt atacacataa ttaaagtcat ccaccttttc ctcttcagac
    24661 aactgattct tttgagaata agtagaatta cctaataata ttataaatgc taaaataatt
    24721 actaaaaata atactttctt tttcatgtaa ttctcatcca ctttcagatt ttatatttta
    24781 atacattgta tcattatttt attatcacct aaacagttaa aagaaattct tgaagatata
    24841 ttccactatt attctcttta aaaattttta tttgtatttt caaaattatt tcatgaaagt
    24901 tataaaataa caattatatt caaatatcta ttttactgct atatcctgaa agtaaattct
    24961 tatcagtgat atactaaaaa agatatgcta aaaaatttat ccattataat gacttaaatt
    25021 tagatacttt actgattttt atttattagt tgagaaagat attgataatt aaaaatattg
    25081 ataactatag aaatgattat tttttataga aattttaagg atataaacta attatactta
    25141 agtctatatc cttaatttat catgattatg agaattttta caaatactta tctttgtccg
    25201 ttttagaata aaaacaagaa catatcctgt tattttattc aaacatccaa gtttaattac
    25261 tacacaatta cttattagaa attgtatcta cttcatatat atatctgtta agtatagctt
    25321 ctagcatttc ttgtcttcca gacttattct ttataactgg catttgcagt gcataagatt
    25381 ctaactcttt aaatccaacc ttaccttcta ctatatcctt acctatacct tcactaaaac
    25441 ttgcatatct ttctttagta aagttttcaa atacctcatc ttctaataat ttatgagcta
    25501 ttaataatcc ctttgcaaat gtatccattc ctgcaatata agctaggaat aagtcttcta
    25561 cctcaaaaga tgctcttctt actttagagt caaaattaaa ccctcctggt gctattccac
    25621 cttgctttaa cacttcatac atagcaagtg ttgcatcata tatatttgtt ggaaattggt
    25681 ctgtatccca acctaataat aggtctcctt gatttgcatc tatactacct aaaacattgt
    25741 ttattcttgc tatatttaat tcatgttgga aagtatgtcc tgcaagtgtt gcatggtttg
    25801 cttctatatt cattttgaag tatttatcca gattatactt tcttaaaaat cctaaaacag
    25861 tagcagtatc aaaatcgtat tgatgtttag taggctcttt tggcttaggc tctattaaga
    25921 attgtccagt gaatcctatt tccttagcat agtctacagc catttgtaag aatcttgcaa
    25981 agttatccat ttcaagttct gtattagtgt taagtaaagt ttcataacct tctcttccac
    26041 cccagaatac aaaattttct cctcctaagt acttagttat ttccatagct tttttaacct
    26101 gagctgctgc atatgcatat acatctgcat tacatgttgt agatgcacca tgaacaaatc
    26161 ttggatttcc aaacatattg gcagttcccc ataataactt tatacctgtc ttttccatat
    26221 taacttttat atactcaact atttcatcta atatcttatt tgtctcttct aaatctcttc
    26281 cttctggtgc tatatctctg tcatgaaaac agaaatactc aattcccatc ttagacataa
    26341 attcaaatcc tgcatcaact ttaatctttg ctatctcaat tgggtctgtt atattattcc
    26401 aaggtctctc tactgtgcct actccaaatg ggtcattacc ctctccacat aaagtatgcc
    26461 aatagctcat tgcaaatctt aagtgttctt tcatagtctt attacctacc acttgttcag
    26521 gattgtagta tctaaatgct aattcattgt cagattttac tccttcaaat tttatctgtc
    26581 ctattccttt aaatatttca ctcatttcat gtcctcctaa tattttacac atataatata
    26641 tgtagtatgt tttcttaatt taaaactatt ttctatcttt atttttcttt ttaagctaat
    26701 ttaattattt atttttgcat taactacttc atctaataac ttaaagtcat ctttcaaaga
    26761 tttgtatatt cttttataca atctatgata tatattgtat gtatctacat tttcacttat
    26821 tggttctaat ttagttgaag tttttattat agcatcacaa gctttttgta tattttcata
    26881 tattccagct cctactaatg caagaattgc aactccaagt gctggtcctt cacttgaatt
    26941 tatagtatat acatcttgat taaacatatc tgcttgcatc tgtctccata ctttactttt
    27001 tccacctcca cctgaggctc ttacttcatt aacgtctata ttaagattct ctattatatc
    27061 catacagtct ttaagactat atgaaacacc ttccattatt gaccttgcaa tttctttttt
    27121 agaatggatt ggagataatc caaagaacac acctcttgca taagggtcaa gatgaggagt
    27181 tctttctccc atcatatatg gtaagtaaag caatccatta catcctgttg gtactttact
    27241 tacttgatta tttataatct catatacatc ttcacctaaa gaatttgaaa cttccacttc
    27301 actttgacag aaattatctt taaaccattt taatgacaag ccagctcctt gagtaactcc
    27361 cataacatgc catgtatttg gtattgcatg acagaaagta tgaactctac cttctttatc
    27421 aatttttggc tcttttgtat aagcaaatac tacacctgat gtacctatag tagatgaaac
    27481 tactccatct ttaactattc catttcctat agctcctgct gcttggtctc cagctcctcc
    27541 taccactatt gttccttctt taagccctgt caaacttgat acatctctag tcacataacc
    27601 tgtaatctct tgtgattcat aaactttacc taaaagattt ttatctatat ttaacttttc
    27661 tagtacttca tcgctccaat ctctttttct tatatcgagc aactgcatac cacttgcatc
    27721 tgatacctct gtagcatatt cacctgtcaa tttgtatctt atataatctt ttggaagaag
    27781 tattttatta gtatttttat atatatctgg ttcattgttt ctaacccata atatctttga
    27841 tgctgtaaat cctgtaagtg ctggattagc agttatttca atcagtcttt cttcacctac
    27901 taaatcagtt atctcctcac actcttttac tgttcgttgg tcacaccata ttatagagtt
    27961 tctcaatgtt ttaccttcat tgtccagcat aactagacca tgcatctgcc ctgataatcc
    28021 aattcctttt atacattcac tgcttatatt tgaactttga actacttctc ttatagattc
    28081 gactacagct ttccaccaat catttgcatc ctgctctgcc caacctgatt tctcttgtat
    28141 aagaggatat tcatatgtac aactttttat agtatttcct agtttatcaa ataaaactgt
    28201 tttcgtacct gatgtaccaa tatccacacc taatacatac tccaacttca tccctccttg
    28261 aatgccactt cataactatc gttttcctat cctaattttt ttatatttta ggtatatttt
    28321 acttgcttta tttttgttag tatattaaac taacttatga actaataata aaatatttaa
    28381 ttatctttgt caatgcaaaa taacctttta tttttgtgta aaaagtatta caatattatt
    28441 ttaaggagga atatcaaatt ggttactgat aaatacacta ttcgagaaat gaatgaaaga
    28501 ttggtacttg aacaaattat aaaaaatggt cctatttcta gggcaagtat agcttctact
    28561 ataggattga ataaagcaac tatatccgct attaccaaaa aacttattga tgaatctcta
    28621 gttcatgaaa taggaattgg aaatagtact catagtggcg gaagaaaacc catattatta
    28681 gtatttaata aatgtgcagg gatttcttta agtatggaca ttggatacga ctatatattt
    28741 tcttctctat cttacttaga tggaactatt ataaattcta agaaattaac agatatacaa
    28801 gtaagtaaag acaatgttat acaattgata gatgaaatta taaatagtta taacatatcc
    28861 aaaatagaca ctccttataa ggtaattggt cttactttgg ctatacatgg gattacttgt
    28921 gaaaataaag tattgtttac tccatattac aatcttaatg agattgactt atatagcatc
    28981 cttagcaaaa agtatgactt tcctattcat atagaaaatg aagcaaactt aacagcttta
    29041 gctgagaata ctttttcaac tgtacataac tcactactta gtctcagtat tcacagtgga
    29101 tttggttcag gcattataat aaataataaa ttatatagtg gcagaaatgg tatgagtgga
    29161 gaaattggtc acactatcat catgcctaac ggtaaactat gtccttgtgg aaatcgtggc
    29221 tgtttagaac agtattgttc agaaaaaaag gtatttgaac agctttcttc tttagaaaat
    29281 attcctaaaa tagattctga tatagtaaag caactatatt atgaagataa ccataatgcc
    29341 aaaaaagtta ttcatgagtt ttgtagttac ttaacaatag ctataaataa tgctattaca
    29401 acttatgctc ctgaaataat atatttaaat agccaaataa ttagtgatat ccctgagata
    29461 ttacagatta caaaagatat gttagttagc tcttttaaca aaggaataaa tatagaaatt
    29521 tcatcattag ggtctgaggc atctctatat ggtggctctg ctgtaaatat caagagcttt
    29581 ttgaatatac aaaatttaac tttaattaat gaaatataag ggttatgact atatacagcc
    29641 ataacccttt aaattataca ttctaaaatt agatttatta tatagtttat gcaagattag
    29701 ctatattttt taaaaattgt atatcaatta agtattaaca taagtatttc gttttaaata
    29761 ttaatataat cttcctactc atcatcagat aataaatttg cattttgttc aaccatagaa
    29821 atattatctt tacctatttt ctctaatttt gctgccaatt cctttgtatc taaaaaagct
    29881 gattcaataa ccatacctaa atttagccct gaaataattt taattcgact gtcattattg
    29941 gctactaata aagcagcatt gcatggagtt ccacctagta aatctgccat tataattatt
    30001 tctgaacttt ccttgtacac ttctaaagct ttttttaatt tttctattgt tccttctatt
    30061 ccatcatctt gtttcatatt tacagtagga taatctatag aatcccctat tatcattttt
    30121 gcagaattta agacttcttc agccatattg ccatgactca tcaaaataat actattcaat
    30181 ttaatacacc tctttaaatc tataagatgt ctacaagata agttttctta tcatcaggcg
    30241 tcattatagt tgtaatttca attccttcat ctaaaagtct tttaaatgct tctttctctt
    30301 cttcagtaac actgatatta ggtcttagaa ctgttgtatc ttttctactt gacatatttc
    30361 ctacatttat attatgtatt ttaaatcctg cctctacaaa tggaataagg tccacaggag
    30421 acttaacaat taataataca ttttgtcctt catactttcc tgcagtaata ttttttatag
    30481 cagtctcttc tgtaattata gatgacgcta tacctgcagg tgtagccatt cttaaaactt
    30541 gtttttgaac agaattgtta gctactgcat catttactac cattaatctt gtaacaccca
    30601 atttattact ccacatagtt gcaacttgac catggattaa acggtcatct atacgaatat
    30661 ttttaatacc tttcatttcc atatctaata tcatcctttc cttattttaa aatacctaat
    30721 gcatataaaa ttattgaaac aaccattact cctaaaatta agtatatagg ttttatattc
    30781 tttttaagag cccaataaac aatcacaact aaaattgcag gaactaaccc aggcataatt
    30841 tgatctaata tttcttgacc tttcattgta aaatcacctt gttgaaagtt caaagcaaca
    30901 ttagctttta caactgaagg tattaatgca cctacaacca ttaaacctaa aatagatgta
    30961 ctctcagtta aaatctttaa acttttttca attgaagata ttagcttagt acctgatgta
    31021 taaccagcat taaatagtgg tatacttaat aatttcaatg ctacactcac tacaatccac
    31081 agtaagattc caaatggact tccatctatc gccatattag ctgctatagc tccaaaaatt
    31141 gtccacggaa taacgacaaa taaactatct cctaaacctg ctactggtcc catcaagcct
    31201 gttttaattg aagcaacagc ctcttcagtc tcttcacttg ataactcctc cattgctaca
    31261 ttaataccca aaatataagg ggcaacccaa ggattagtgt taaaaaattg taaatgattt
    31321 aatacagcac tttgtaactt ttctggatta tctttgtata ctacttttaa aaaaggtagt
    31381 actgcataac agtatgccaa ggcctgcatc ttctcataat ttgaagaaac agaactagta
    31441 aaaaaccagc gccataagac actttttttc accttttcat ttgatttatt taatgatacc
    31501 ttatcactca tcttcgtcca tacctcctac tacagtatat tgttgttctt gattttccaa
    31561 attctttttg taaattataa gtgcaattgc tccaccaatt aaagctacac ctaataatgg
    31621 tactttcata tatactgcta aaacaaaacc aattactaag taactaaaat actccttagc
    31681 aggaagatat ctaagtaata atcctatccc tactgctgga agtagtcctc cagctactgt
    31741 taaaccacct gttaaccatt caggtgtata tttcaaaatg gtattaatta aagaaggtcc
    31801 aaatattaca gatagagcaa ctggaatacc tgttgtagct gctgttaata gtactcctaa
    31861 catttgcata taggttatat ttttataatt tcctttttta gctccatctt ctgctttatg
    31921 aactagccat ataccaatag tatttctaag aacatctaat tgtaccatca ataaagcaac
    31981 tggaatacct atagagattc ctacagatgc ttcttgctta gtcgtaatag ttataaatgt
    32041 ggctactata cttgctgttt gataatcagg tattgatgct ccaccaaagt tactaatacc
    32101 taatgataat agctgtaatg tacctccaat atataaccct gtatttatat ctcctaagat
    32161 aagaccagta ataaaacctg ctgttactgg ttgatatgtt ccaaacattg ttgaattttt
    32221 ttcatagttt ataaaaaatc catatagtac gattaataat aattgccata attgtggctc
    32281 cattatgatt tcacctctcc caaaatattt tttagttctt taaaattata actggaatct
    32341 tgctttagga aaataggaat ttcttccagt gggcattcaa cttcataagt tttcccacct
    32401 tcataactaa ctccactaaa tatattttcc catgtatgtc cttttggtaa atatactttt
    32461 ctacttctat ctttataatt cattattgga gctactaaaa tttcatctcc aagcatatat
    32521 gtattatcca cctcccaagt tttatcatct tcaggaaatt cataaaataa agttctcata
    32581 actggtgttc catcttcatg cgcttctttc atcagttttt ttaaataagt ttttaagctc
    32641 tctctaattt ttatgaattt tgtaagaatt acttcaactt cttcaccata agaccatatt
    32701 tcattaggag ctccagttac cattgagcct ccacctttat ttgataatgg tttactatga
    32761 ggcaatctat ctccatgcat tctcaaaatt ggtgaaaaag tagcatattg gaaccatctt
    32821 accataagtt ctctaaattc tgggtcttta ggatttcctc catggaaacc tccaatatca
    32881 gtagtccacc atggtatacc tgccagtccc atatttaacc ctgtatttac ttgattatta
    32941 aaagcttcaa aactagaatc aatgtcacca gaccatacta aagctccata cttttgagct
    33001 cctgcccaag ctcctcttac aagagttaca acagactcta tgtcattatg taaaccatca
    33061 taaatcattt ttaaataatc aataggataa atattaccac aacttaaaac atttcctttt
    33121 ttatatctat agttatcaaa atcatacaca gaatagccag gttcagctac atctaaccaa
    33181 taatagtcaa tcccaagttg tttataattt ttatctattc tatcccaaac atattctctt
    33241 gcattttcat ttgtcatatc tacaaagact gtatttcctt gaatttgcat tgtcattcta
    33301 acaccacgat taacattgac taaatagcca ttttctaaat aatcattgta gttttctgca
    33361 tcactttgaa ctgtaggcca tacagatact attggttcta ctgaatactc ttctttcaat
    33421 tttttaacta attctttagg atttttccaa taatctaagt caaatttata ttcaccttgc
    33481 ttaggccaat gaaaatagtc aattgcaatt gatgaaagct taattcctct tttagaatat
    33541 tccttcacaa catctaaaac ttcttctgaa gttctatatc ttagtttact ttgccatagt
    33601 cctaaaaggt tttcaggcat cataggaaca gttccagtaa cttgagagta atttttattt
    33661 aactcttttg ggctttctcc acaagtaatc caataatcta taaaatttgt agaaaacatc
    33721 ttccattctg tcatattttt agcaaaagat acttttccaa ttcccggatt attccataaa
    33781 agtccataac ctagactaga aatataaaaa ggaactgata tttgagaatt tctttgggct
    33841 aactccaaaa cagtattctt taaatctaaa aatttatgtt gatattgtcc cattccaaaa
    33901 atcttttcag aaggctcaga ttcaaatcta gtagttactt caaattctcc actatagctt
    33961 ggtcgatatt ctcttgattt taactttaga gtagagttaa agtctttggt aatctcaatt
    34021 gtccctacat cttctccacc atcatcatgt tttacagctc ttaatcgaat atattctttc
    34081 aataatattt catttttatc attataaaaa gtaattctat ctctatggtc taagacagct
    34141 tttatctttc catttttaat gattgcactt ccatcttcat ttttattaat tgtaatatca
    34201 tctttattta acttaggttt ttcgttaaga gcatagtttt catcaacaaa attttggtct
    34261 acaaacgacc taatacgtaa agagtttttt ccccatgctt ctattcgcaa tagttcattg
    34321 tcaaatcttt tttcaatata gtcttcagat atttttatca cggctacctc ctaaatcaat
    34381 ggtataatat tctatctttg tgtaacttaa gttaaataat gtcgtttagt atcgttattt
    34441 ataaattagg ttttatatat aattcatttg tacattaaac taacttacca ataatatact
    34501 ttatttgact ttgtttgtca atcgctttcc ggattttagt aaaattttct aatatattgc
    34561 tggaaagttg ttcttaatat cttttattta tacttttaat atctgtgatg atacctatat
    34621 acatctagtt tttttaaaac acatacagga ataacatttg cctattatgt agataatatc
    34681 ggacttgaaa atatgtatag tgaccttata aatacagata ataatatatt agatattgtt
    34741 caaaacaatg gattttataa ttataaataa tttatgaaat tatttaagaa aatatacaat
    34801 tgtataccaa gtcaaaaacg acaacaaata aataaaacta aaaaagatgt tgtctcaaaa
    34861 tatagataaa tttatttttc attgctaaaa tgattaaaat atatttgatt taatatactt
    34921 gatttaatat aaaaaaagag tgtctcataa actaaaaagt tcacttttag acactccttt
    34981 atatatatta tctacttctt aattcattta ttacctttct acattttctt tcagctagtg
    35041 gatacatctt tataagtact aattactcca cttaaaaatg gttcctgtac tgtccatcag
    35101 tcatattttt ctgccaaata taatggtgtt tcataatgag acaataaata tttatatctc
    35161 tacttatctt ctctaagctc gtcaaatcca actataggta tctctaaatt atattcttta
    35221 agtagctttt ctagctcttc tataaaaata cctttcccat ccaccatttg tatatccttt
    35281 attttatcca tcaattcatt gcaaccactt aactcaccaa accaacgttt agaactacat
    35341 gtcttattat aaccacaact tggactgcca tctattgcaa tgatactttt tatatcataa
    35401 tcatttttta aatattcatc aaactgcctt acatgaggta ttaacatttg cctacattgt
    35461 tctctaaaaa acaaattgtc aaactgttct tttacatgtc cccacctatt tattccatac
    35521 ataatcattt ctgggcatgg tagttgaatt attccatacc ctttatttat taaatttatc
    35581 gctatatttt gtgctccctt aaattctgac aatccctcca ctttagaatt acaatttaat
    35641 atacaatgac atactactac aatctctcta tttcttttca taataatctc cttagttatt
    35701 cttaatttta atgatactac atattttgat aattatatta tttatttgtt ctatatttcc
    35761 aatattctat atagaaatat acaattagta atcttttata atctatacta tgataaatgt
    35821 atatattttt ttaggaggta ttataattgg atactaaaaa agtcacattt tcttcaatgt
    35881 gcatagttat taatattgtc ttaggtatgg ttatatctat gataaatata ccattattat
    35941 ttttagatac agttggtact gtacttgggg ctgtcgtatt aggtcctttt tggggtgctc
    36001 ttattggtgg atgtacaaac ttagttttag gtgttatatc aggtcctaca aatatacctt
    36061 ttgcccttgt aaatattgtc cttggtctta ttgttggata tatttctaag aaaaaaggtt
    36121 ttggttataa agaagctatt attacaggag taattttatc tattgtttgt cctttaattg
    36181 gtactcctat ttcagtttta ttgtttggtg gtttaagtgg aagtggtgct gatttattgg
    36241 ttggtttttt agttcagtct ggtcagaaga tatttactgc tgcgttcttt ccaaggattc
    36301 ttagtaatat agtagacaaa cctttgtctt gtattatggt ggtatatttt ataagtaaaa
    36361 tgcctaaagg ttttataaaa caatatagta aaaatacttc tagttcatat taataaatca
    36421 tttattatgt aaggtttatt actctttaaa atgctatata ctcattttta tataacattt
    36481 ttattaataa tttaattaga tagtatttgt attactttaa ttaaacgtaa cctcttgata
    36541 taaatttgag ctataaatct atatcaagag gtgctatttt atttttaata taattaatat
    36601 tctattacgc aaaaaatgca tatatttcat tattttatgg aaaatattac ttcatttaac
    36661 tctatatcaa actcattaag taaaaatcta attatattta atttagcctc tgtatttaaa
    36721 tttgtttcta aatatatatt ttctgatatt ttaatacctt ttcttaattt atatgcatct
    36781 ctagacttaa tattatctat aaaatctctt ttataagttt tgtctacaat actgttaaac
    36841 cttacagaat ccaaatcata taaagtaaga gcaacttgtt cataaaattc tgtccaattt
    36901 ttagccttat atgactctcc taatatacta aatgatacta tactttcatt tgtaaaatta
    36961 acatcatcat cctctaacgt aaatatattt tcactgttac ttggaggttc atatgtaaca
    37021 cttggatatt tccaaatttc tacagctcta tctagtaata tcttagttct attttttatt
    37081 tcttcttcat tccatttatc tatagatgaa atatatttat ttagataaag cctactatct
    37141 ttaaatccat cttccatttc tttcttttct tcaaatgttt tattacttag ttttgaatta
    37201 tatcctgtca aagttaaatt tccaattgta tgtaaatatt tatcatgtat ctccttatag
    37261 ttatctccta gtgattcctt ccatttattt gttaatgtct gtggcattat atgctctata
    37321 tttagcatat tattattgat taaattttct aaatcaacaa tttctttatt actataattc
    37381 tctaacctct caagtatata taacttattc tttgacttag tattatatat atctttagtt
    37441 tcaaaagcat ttgaaaattc actgtcagta ggaaatcttt gagatgattt cttatttata
    37501 aaaatatatc ttaatatatt agaatagttt tctttataat cactaaattt tttaatttcc
    37561 cttcctaagt tcataaatac tttattcagt gcattcggag gtacatcaca tactattctt
    37621 cttaatataa aacattctac taaattaagg gattctacaa gtactttttt atttattata
    37681 ccttcattat aatcatcaaa taattctaat ataaacggat atgatacaaa tatttcaagt
    37741 ttgtttatcc ttttcaaaac tttgtttaca tcattatcat cagtacatga ataagatatc
    37801 tctctataat agttagaaaa tttaagtaaa tcttttaata aaatttctat atctatacca
    37861 ttatctgata catacctttt aaaactaaaa tatactttat ttttattcgg tatacttctc
    37921 tcctttatag tcaaatagtc tcttataaaa ctacttacgt tgctacttgt atttttttca
    37981 attttatacc aataattatt ataaaattcc tcttgtaact tagagcttct acccattaac
    38041 acaaagtttc ttactctatc agcttcactt aaatctaagc cagttgaatt tagactttca
    38101 aagattaatt gagggtcatc ttcaccattt tttaactcta tttctactat agttaatttc
    38161 tgtatagcat caaacaaatc atctattgat atattatctt cttttattct attataaaaa
    38221 tataaataat ttgaaactat attagaattt ctatctgtat tcatttcttc ttcaaatagt
    38281 tcatagtacg cttttctatc ttctgctatt ggttttaact ttatttttcc atctttatct
    38341 cttgagtgct tgtttataag ataacactcc ttaatctgtt cttctgttgt aataattcct
    38401 tttgattccc caaactcttt tattatttga cacatggcaa tcaataatat tgacacagta
    38461 gtcactcttt gttgtccatc tattattaaa tattcttttc ccatactata tatagataca
    38521 actgacccta agaaatgagt tctaaatcca gaatctatta tatcctctaa atcatcaaac
    38581 aatcttttac attgttcttt cttccagtta taatttcttt gatatacagg tactacaaaa
    38641 cttttgtttg acccctctaa ataactaaga aattcaattt ctcctgcttt catattaact
    38701 ccccctataa gttaaataaa ttccattcat aactccatgt atctatatat tatatcaaaa
    38761 ttttgactca taaatgtata tgaaagcctt attatatacc tttttatacc tgtttttatt
    38821 ttattaaagt aaatacatga ttattctata aaatatacaa atacttaatt ttaaaaatta
    38881 ttatttaatc ttcttcatga gtaattcata gttatttatc aattaaaaag agatattgca
    38941 taattattca atacctctct ttgtatattt acattatcca tatctagtta tctatttcaa
    39001 cccaatatta gactacctac taataaattt attctctaca tcattaacaa taattttgca
    39061 ctaaataaca tcattagcct atctctgatg cattttcttt aattttattt atagttttaa
    39121 tcaatttatt tctctcttca atatgatttt caaataaatc aattatactt ccaacagttc
    39181 taaatgggtc ttccatcaac actttgttat cctctataaa tccattcttg actacataat
    39241 cgactataag tttaacaaaa tgtatttgct tagtattaaa gctcttatta tttaaaaact
    39301 ctgaaaaagc ttcatttgca gcttctctat ccaatcccac tagtcttctc actaattgac
    39361 ttactggagt atctccaaac tccttcttat aatcatcaca attacctaac tgttttaaga
    39421 gtatttcctc caacgtttca acatcttgct ttgttatctt tttattattt cttaatttaa
    39481 atattgctaa ttcatcttta tggctattta aataatactc taccttcttt ttataattct
    39541 taagattgtt tgcattatat acagaatcat ttctatcttc tgctacaatc atatcttcaa
    39601 aacttgtata atatatcttt tgactagact tttcaagata cttaataagc tctcttaatg
    39661 atatacgtac ttcttctacc tcaaatatat ctgaatcttc ccaaaaattc tctgtcattg
    39721 ctttttcaat agtatatttt tgttgctgaa tctgtggtat agtcccaagt tttgaaagtt
    39781 tttctgctgt agccattaca tgccttatac ctttacttgc attattattt tgtaagtatg
    39841 caagttgtat attatacata actacatcaa atcttttagc caattcatca tcactatatg
    39901 aagttatgag tggtgatata tattctctta tctcattttg tgctactgct ccaatattgc
    39961 tccaaacatt ttcattttta tacttatgta cataacttaa attcatccta actatataac
    40021 tatcctcatt taaagctttt acagaagtta taagttcttc taacaattct tttctaagtt
    40081 ctgcatactc accttctata tatttaatat cttgaagttc tttaaccata cttaccttta
    40141 tattaaataa tttttcagta agtgtttctg ctttatttcc ctcaaatcct ttaggattaa
    40201 atttaaaaaa ttcaaaatta ttacaaaaat caaatattaa gaatctctcc ttatccatat
    40261 caacacctaa taaatctgga cataatctag ttcctctacc tatcatttgc caaaacttag
    40321 tcttacttct cactttcttg aaaaaaacaa gatttagtat ttcaggtatg tcaattcctg
    40381 tatcaagcat gtctactgaa actgctattt gaggtaattt attcttatca gaaaaatcat
    40441 ctattataga atctacataa tttatactat agtcaactgc ttttacaaag ttcccaccat
    40501 actttggata cagcttatta aatctttcaa ctattgccct agcatgcttt gtattctttg
    40561 caaaaattat agtcttacca atcttttctt ctccttctat tttcaacccc tctgtcatta
    40621 gcttatttaa aactaaatct attgtgtcag aattaaatag ccactcattt actgcattat
    40681 tccctatttc gtctccaata ctctcatcat cattaaatgt attttcatat tcttccttct
    40741 cttcatcaga aagctcatca tacttaattc catcttccat aatcttagtc ttaaactcaa
    40801 tactagtata atctactaaa tatccatcct cgactgcctt attatactca taagcatatg
    40861 taggtactcc attttccatg tcaaaaactg aataagtatt tttatctatc tcatcctttg
    40921 gtgtagcagt aagacccatt aagtaagaat caaaataatc aaagattgac ttatactttt
    40981 tataaatact tctatgcgat tcatctatta taattaaatc aaaatgacca ggtgtaaaca
    41041 atctctttcc atccttagac ttcgtatcat caattgcatt catcattgtt ggatatgtag
    41101 aaaatatcat cctagcatct tctgggctgt ctttgctatc caataaatta cataacgcca
    41161 agttaggtaa tagcttagta aaactttttt tagcttgctt taccaatgct tttctatctg
    41221 ctagaaataa tatattttta atccaattat gtcttgaaag tacatcaact atagatatag
    41281 caattcttgt ttttcctgta ccagtagcac ataccaaaag agttttgcgt tgcttatttt
    41341 caagggcctc acatacagcc cgaatagctt ctttttgata atatctattg gatatttcat
    41401 catttattgt tacagaactt aaagacttct tactctttct tctatccatc ataagttgta
    41461 attctgattt tttataaaat ccataaactt ttctatctga atagtcatcc caaatataca
    41521 tatcaaaacc attagtcaaa aatattactg gtctttgact atatctcttt tccaaacaat
    41581 ctgcatataa tttagcttgt tgttgaccaa tttttgggtc tttgctcgtt cttttcgcct
    41641 caactactgc taatggctta ccattttcac cataaagaac ataatctaca tatcctacac
    41701 cactttcatt aggcatacct tgtacttcta tttcctcccc tatatctttt ccaaattccc
    41761 aacctgcaag ctttaattct atatttatat atctttttct tgtctcaaat tcgcttactt
    41821 cgtctatctt gaaatcatag tttacagtat taacttttct cttttcagtt agtgactttc
    41881 ttaattcctc attttctttt attacttctt caagcttttt atcttttgaa cttaatctct
    41941 cgtaaagatt tttaagttcg tctggtctcg tccttttctc ttctccatga agtaataaat
    42001 cttcattaaa gtcttctgct gtatattcat ctgaataaca atagtctatc caactaacaa
    42061 attgatgcaa attgttaagt gaaagtattg cttctcctct ctctatgttc gcactagtat
    42121 gtacagataa attacctaac ttaactatat attttaataa aggtaacata tcatagtcta
    42181 taagttctat aaaactatta ttatgaatca acgtactgag attatcttga taaggcaata
    42241 ctaaatcact atcattagca tatagccatt ttactgcaag ctctaaagct cttcttgtta
    42301 tagttgcaca agtagatgga ctaactagta tacttttttc tgcttctaag caagcagtat
    42361 taaaactatt gaaatttttc ttcttttgta aaaaatcaaa attacccaag gcttttatcc
    42421 cccttttgtc ccttagttaa aataaatctc tctaaaaact atttcttaca gctgtttctt
    42481 atactaacaa atacttcttc attttctgta aacaattcgt acatatcttc aaactgtggt
    42541 atatcatatc catgagaatc atcatttctc aattttctaa gtgtttctat aactatagaa
    42601 gaatttttag gtaataaatt gtgatactca caagctaaaa ggtagtcata aaagttttta
    42661 gattttatgt ttaaatcaat tgatttataa tacaacattg cttttgttaa ttctagaaat
    42721 gataccatat agcttttaaa gccttctttt atgtatctag cccataactc aggcatttct
    42781 tccttatcat ataagatttt gaagttttgc aggtcataca agcaagaacc aaaatcccta
    42841 tttacttctt ctattgagtt ccaagataat ttgtttctaa ttaccataca tgtccctcca
    42901 atctaagata tctattacat cactgttttc aaaatagaat ttatttatat aatccttaaa
    42961 atctttagat tcataaataa cttcaccttc taaaatagct tttttaagtg ctattgtata
    43021 attatctgta acaattttta ggtctacatc aatgtctaat atatttctta gagcttctgt
    43081 cttagttgca agttctgtaa ttggtacttt tttgatggga atccaagcta tgtctatatc
    43141 actttctgat gtatgtttat ctgttccata actaccaaat attatgattg ctagagtatt
    43201 ttcttttgga aatacattta ttattgagtt tttaatctca tttggtatat ttctcattta
    43261 atcacctctt gtttattagg taatattgtt tagttaaata attctccttt gaaagctttt
    43321 tgcattaatg aattaaagtt atcttctaac tcttttaagt tggtttctat ttttaatttt
    43381 aatttatcca cttgcttaac aaactcagaa aactgatttt gaaattcaat tggaggaacc
    43441 attattaaat attcacctaa cttactaact gataactcaa tttgattcgt tgaaccatta
    43501 acacattttc tatatattgt gtcttgtata tttgtaaatt caaataacgc tgcaaaataa
    43561 tctgaattta agttatttga aatacttctt aaaactgtaa catgactatc tgctatatat
    43621 tcagaattat caattttgtt aaattttaca catcttccta atgtcccagt tccagtagaa
    43681 tttattaata tatcattttg tttcaaaaat atatcttcta tcttctcttt taagttttca
    43741 tcataatatt tacaattttc taccttcaaa tttctccagt atatacattt ttgatttata
    43801 acttttatat ttgattgctc tacatattta ggagatacac ctctttttaa atatatagaa
    43861 atctctttaa tcttcttcat atcaaatttt tttgtattat taattggctc cccaaacatc
    43921 tcaataaatc ttgatttaac taattcatcc aatgcttcta tttgctcttt tcttttattt
    43981 attaactctt gagctttatt taaaacttct accattttat tttgtataca aattgtgaaa
    44041 tatggtattt ttatatcatt taacttgctt ttatttaaag ttgcacccat aactgctcta
    44101 tcagtattat taaaatttaa agttctcaaa gcataatata aatattcaga tgttataagt
    44161 tcattatttt ttatttgaaa gttagcaatt gcttcatttg taaacatgtc ttcttttaat
    44221 atggcaactc tacctataga caacttaaaa ctcattacaa cggtattttt aggtactaat
    44281 ttcatattag ctttttcaac agctaaatct gttatctctt cttttgattt tgatatatat
    44341 ttttctttca aatcagaaat tgataaccat ctattaccac ttccccaata atcagaagta
    44401 tttctagatg gtgttttgcc aatatttata tagcacaatt catttaattt tatatactcc
    44461 ataccctata cctctaacat tctttctaat tcttctaatc caacagctat ttccttctct
    44521 aactccctaa ctctacctat aatcacacta ggagcatcat aaactacttc ctcatacact
    44581 acctctttat acttattaat agataaatca tacccattct ctcttatctc ttccacatca
    44641 acaaaaaagc tttgttctgt tctttttcta tctacttccc catcaagatt atcaaatctc
    44701 ttaataatat cctctatatc actatccttt atctcatttc tcttatcatc caaagaataa
    44761 ccatcagctt tcatatcata gaaccatacc ttatcagttc cacctgtccc tgttttagta
    44821 aatatcatta tagctgtaga tactcctgca taaggcttaa acactccact tggcattgat
    44881 attatagctt ccaatttatg attatcaact atttcttttc ttatcgattt atgtccacct
    44941 gttgaaccaa acaatactcc atctggcact atacatgcgc atcttccacc aatttttaaa
    45001 actcttaaaa aaagtgccaa gaataataac tctgttttct ttgtcttagt cacttttaat
    45061 aaatctgctg acactgcttc ataatctaaa cttcccttaa aaggaggatt tgctaacacc
    45121 aatgtaaact tatctttatc tgtattaacc tccgataaag aatccttata ctctatatta
    45181 ggattgtcaa cgccatgcaa catcatattc atagcaccta ttctaagcat agttctatcc
    45241 atatcaaatc catagaacat accattatta aaatgctcct tcagcccttg cactaagaaa
    45301 agacttgaat gattatccct taagtattgt tgtgatgata ctaaaaaacc tgctgaacct
    45361 gctgccgggt ctactataat atcttctggt gttggtttaa taagtcttac tatcatatct
    45421 attatgtgtc ttggagtcct aaattgacca ttagtacctg ctgtagccac tttggataat
    45481 aaatactcat acaaatctcc ctttgtatct ctatccttac ttaattctaa attactaata
    45541 ccatcaacta ttttagataa cataagaggc gtaggaattt taaatattgc atctcccatg
    45601 tactttgcat aagctgagtc tttatttcca tgtaattttt ttatgaaagg aaacacttca
    45661 ttttgtacta tttcatacat tttttctgaa tttccttcat tagaaaactt actccatctt
    45721 aaatgttgat gttcatcatc aaatatcctt tcaaaagaaa ctcccaaaag agttgcttct
    45781 gcttcatttt ttgtttctac ttcatccaat cctttaataa ataaaagata tgtaaattgt
    45841 tctataactt ctaatggatt agttaatcca ccagtccaaa atgtctccca aatcttgtct
    45901 actttgctcc ttaattctcc tgtaatcata tatgactttc cctccagtgt tcataaaata
    45961 atttaaatat atattttagt cgtacgcctt aataattagt gtcttatatt aaattcaaaa
    46021 ttttactaca cagttattaa attatttttc ctatttacat gttttagtta aaaaactaat
    46081 gcaatactct tattttatga ttattataca tcccatacaa aattatttta tcatatatcc
    46141 agcatagaag tcatctacct ggataactct taccatatta taacttttta atattaattt
    46201 aaacttagaa agaaattttt tatttaatta tatcatcttc cttatttcaa atttctcaat
    46261 tacaatctca atcaaaaaat aaaataagat gctgtctcaa aatagatata atcttctttt
    46321 ttattttcgg aatgatgaaa atatatttaa tttcatacaa aaaagagtgc ctcctgaact
    46381 aaaaagttca ttttgagaca ccccttaatt taatcttact tattctctcc ctttattatt
    46441 aacacttcac tatctctatt gcttttccta cacatccaca aacttccatc ctactcttaa
    46501 caaaatcttt aactgactct aaaccttttt taccatattt cttagggtca attacctctg
    46561 ggtcagaatt aagcacatcc ttaaccccat tgctataagc aatccttaat tcagttgcat
    46621 aattaacctt gcaaatccct ctttttatag attccttaat aacttcatct ggtattccag
    46681 acccaccatg taatactaat ggaactgata caacatctct aatttcagat aatctatcta
    46741 aatcaagctt tggctctccc ttatataatc catgtgccgt acctattgct actgccaaag
    46801 atgatacccc tgttctctct acaaactctt ttgcttctaa tgggtctgta tatgctcccc
    46861 catcaccacc atctaaatcg tcttccttac ctccaacttt acctaattca gcttcaacag
    46921 gtatatctga aggcatacat gcatctacaa cagatttaga tattgaaata ttatcttcgt
    46981 aactttcatg agaaccatca atcataatag aagtatatcc aactctaagt gcctgcatag
    47041 ctagtccaaa gcttgaacca tggtctaagt gcattgctac tggaacactt gccttctctg
    47101 atgctacctt tacattcgct aaataataat ctagccctgc atactttatt gttgaaggtg
    47161 ttgtttgcaa tattactggt gatttaagtt cttcagcagc ctctattact gccataacca
    47221 tctccatatt ttcaacatta aatgcaccta ctgcataatg tccttcttgt gcatctaata
    47281 atatttgttt agttgtcact aatgccataa tttctcctcc tatatgttta tactgatttg
    47341 atttcttcgt tatttaattt tgctactatt tctctacttg ttttgctatt taataactca
    47401 tttaaaaatt cttcattcat taattttgaa gatagttgag ataatgtttt taagtgtaaa
    47461 ttatcaccat tatctgtagc tgctatcata aatataatat gtgctaagct tccatcttct
    47521 gattcaaagt caaacccttc ttttgataca cctactgcta cacgtggtac ctttactgca
    47581 tctgtttttg catgtggtat cgctatcccc ataccaaaac ctgtagatga tatttcttct
    47641 cttttaagga tttcttcttt aaacttcttt ttatctaaaa gaacactaga tttatcaagt
    47701 attccaatca tttcatcaat tacatctgtt ttattttttc ccttaacatc taaaattact
    47761 gtttcttcgc tatataaaga gatattatta gatacgtttt ccgattctgc actttcattt
    47821 ttatgttcat cttttgttac atttgtattt tctatagtat ttttctcatt tactacttta
    47881 ggtgtaacca tcatataaag tacagcacct actaatgaac ctacaaatat acaccctacc
    47941 cataaaagtg gcttattgac taatcctaga accaaaaacc ctccatgtgg agctggtact
    48001 tctattttca ttatataagt taaaattgat gatattgatg atgcaatcat aagtactggc
    48061 aacactttta atggattttt tgctgcaaaa ggtattgccc cctctgttat atgagtacta
    48121 cctagtatat aattgattaa tcctgctgct ctatcttctt ctgtaaatct atttttaaat
    48181 aaagtagatg ctattgctat taccaatggt ggtgttatac aagctgcaga tacacctgcc
    48241 ataaataaat aatttccctg tcctagaagc atagttccag ttacatatgc tgctttattt
    48301 actggacctc ccatatcaaa tgctgacata catcctatta ctattcccaa aattataggg
    48361 cttgaatttt gtaaccccga tagaaagttc atcatagcat tgttaagtgc tgaacatggc
    48421 ccaccaagta acaacattgc tacacccaca agacctacgc tgacaatagg aattataaaa
    48481 atcgatttaa gaccttctaa ttgtcgtggt aattttctta acaaatgtac aaatagttta
    48541 actaagtaac ctgctaaaaa tcctgatatg attccaccta aaaaccccga acctgtatca
    48601 aatgatatca ttcctccaac aagtcctgct aacataccag ctcttcccga tatagattga
    48661 gctataaatg ctgccaatac aggaaccatc aagttcatag aatatccacc aacagatttt
    48721 aatgtagctg ctatttgatt atattgttct gaatttgggt caaatgaata aatcccccat
    48781 aaaaatgata tagcagtaag tactccacct gctactacta aaggtaacat gtgagataca
    48841 ccattcatta agtctttata caacttttga ccaaacgata aatttccttc ttctgcaatt
    48901 ttactgcttg ataagtttcc ttttctaata gctacttttc catcaataca tctttgtata
    48961 agttcattag ctttatgtat accttctttg acaggtactt ctattactgg ctttccattg
    49021 aatctgtcca tatcaacatt tttatcacaa gcaactatta ttgcatctgc catttcgata
    49081 tcttttgctg ttaacttatt ttctacacct atagctccat tcgtttcaac ttttatgtca
    49141 caccctaatt ccctggctga attttttaat gcttcttctg ccataaaagt atgagctatt
    49201 ccagttggac aacctgttac ccctagaatc attttctttc ccatttttat accacctttc
    49261 tgactcttat attttttata taatcttcca cattctccaa attacctata ccattacttt
    49321 cagccacact tgctcctgtt gctgctgacc tttttaatgc ttcttcaata tgttctggat
    49381 tttccaacca tatacttaaa aaagcagcta atgcagaatc accagcacat gcagagctga
    49441 ctactgtaac tggttgagca ctagcataat aaattgattt tccattataa aaataagaac
    49501 ctttttctcc taaagttagc aatatatttt gagcaccttt taaatgtagt aatttaagta
    49561 catccttaat atcttcttca tctcttacaa taattccaaa tatatctttg atttcttcat
    49621 catttggttt tatcaaatat ggattatact gtagtaactc ctttaatttt ggtgaactta
    49681 tatcgagtat tgtctttata cttttatttt tacaaatttt aaatatatcc tcatagtaat
    49741 tatcatcaat accaggaggt agacttccac ttattgataa gtaacttata tctgctaatg
    49801 actgtatctt atctagcata tctagttttt gtttttcatt tacatatgac ccagagttta
    49861 caaatttaaa ttcatcactt ccatcattta aaaatatatt tatacgagtt gtatcttcta
    49921 cccaagtagg caatacgtca aatcctctct tttcgctttc ttcaactata tattttcctg
    49981 aaaatcctcc aaaaaatcct aatatcttag attctatacc ataatgacct agtacaaaag
    50041 ttacatttaa tccctttcca ttaggagaat atacagcatt tgatgtacga tttactaatt
    50101 ttctctttat cccattagta gatatattca tatctattgc aggatttgta gttaatgtat
    50161 atatcattgt cttccccctt gcttgtgctg tgtatgtttt cattataata aaaaagtcta
    50221 tgaaaatctt ttcacaaata gaaaatcgat tttcatagac ttttcaattt aattttcaga
    50281 attattatat ctgaccatat aatctataat tatcctagat ataatataca agggcaatct
    50341 ggaagatact tcatattcag aaattgatat atgttcatgt ttgtatccta caatatataa
    50401 atccgaatac tttataagtt ttgcactttc actacaacag caagttataa ccttagctcc
    50461 aactaaattg gcattctgtg ctgattctac aagctctatg gtatttccat tcaatgaaaa
    50521 tataattata agttcgtctt tttttattga tttagatttt attttcatta tgttggggtc
    50581 atttataaaa acaacattaa aatcaagtaa ttgcaattta agactaaact cttttgctac
    50641 atattcagta agccctcttg ctaaaatata tatcttacta gatttattta tagtttttat
    50701 tatattgatt agtgtagtta aagatatttg ttctataact ctctgtgctt ctataaagga
    50761 tttatttatt atatccccca tattttgtat atcatcattt tcatctttta ctgttaatct
    50821 atacctaagt tcattgaatc catttaaacc acattttcta attgctcttg aaacggttgc
    50881 tggagatgaa tatgtttcat gagcaatctc tactatagat aattctggta atattgattc
    50941 attttcattt ataaatttaa ttatttcaag ttccgtcttc gttagatttt cagaattact
    51001 tttgtttagc tcaattatca tatgttatct ccccttatat aagttttatt tgtctaaatt
    51061 tatcgagtaa tataatatat tacctcttaa ctacttattt ttatatacaa ttaagattta
    51121 gtcaatgtct atatatgtaa atttataata taataatttt ttgcttaaag tttattatgt
    51181 tatcttatag cattttaaaa taaaaaagaa ttgtacctct accaaaattt ggatgaagta
    51241 caatagatat tcctcatact gatatgttta tgattaaaag tataaatata aatttcgcta
    51301 tgaatcatat aattaataaa tcattttatt tacaattata acccccctta taaaactata
    51361 ttaataatat atacagtatt tataaggggg gttgtttata tttaaaaact atttactttt
    51421 ctcttaattc ttctccatta gttcttatta cattttgata ccaataaaaa ctatcttttt
    51481 tataacgttc tttacttcca tttccattgt tatctatatc cacatatata aatccatatc
    51541 ttttttccat ttcttgagat gaacaactta ctatatctat tggcgaccac atacaataag
    51601 ctaatatttc ggttccatca gctatagctt cacctatttg ttctatatgt tttcctaaat
    51661 aatctattct gtaactatca tgaacttttc catcttcaaa tttatcatgc attccaaatc
    51721 cattttcagc tatcattatt ggcttttggt atctatcata atattgagat aaagtattgt
    51781 ataatccttt tgggtcaatt gcccaccccc aaggatttgc ttttaaatat ggattcttta
    51841 tattgtcagt tggattcatg gtgtttttac ttgctgatac tgttgtagaa taatagtatg
    51901 ataaagctag aaaatccata gtattttctt ttaagatttt atcatcacct tcctccataa
    51961 ctatatttat gttattttct ttgaaaaatc tcttaatata gactggatac tctcccctaa
    52021 aacttacatc agtgaaaaaa tattgtagcc tatttctttt taaagcaaat actacatttt
    52081 cagggtcaca atcttctgga taagatgtac aatctgccat catcatacct atcatcatat
    52141 ctgaatttat ttcttttcca agcttcttag tcaaagctgt agctatgaat tgatgatgaa
    52201 tagcttgata tctagtctct tctacattat caacttggtc tacacaaaat gcaactgaat
    52261 taaatgattc ataatgtatt aaatttattt gatttataac tatccaatat ttaactttat
    52321 ttttatatct atttagtatt aattctgcat atctaacaaa gaaatctacc acttttctat
    52381 tagaccatcc tttatatttt aatactaaat tcaaaggagt ctcatagtga agtagtgtta
    52441 caataggttc cataccatta tctattactt catttataag attatcataa aactttaatc
    52501 cctcttcatt aggctctaaa tcatctccat ttggaaatat tctagcccaa tttattgaaa
    52561 atctaaaaca ctttaaccct agctctttca aaagctttaa atcttctttg tatgtatgat
    52621 aaaagtctat tccactacgc ttaggataat atccattatt atctttcata gcaaacttta
    52681 ttctttctat agtcatatca gactcataag gtttagatat atctctatct ttatcataca
    52741 tatgtacatc agctaaacac caacctttgc caccttcatt ccatgcacct tctaattgat
    52801 tagctgctac agctcctccc cataaaaaac ctttaggaaa cttacccaat ttaatcactc
    52861 cttattttat ttatttaaat catttactat tatttacctt atattctata gactttacta
    52921 ttcctactaa agacatagtt atatttaact cgctgaatat ggtcataaga gtatcttgag
    52981 catgtgcaaa taacagcgaa tgtgctcttt tctctccacc agcttcccct tgtataatct
    53041 tggtttgagc tctatgtgct tctgtcataa acccttttgc tttagctagt tttaaatcag
    53101 catttctata atcaaacttt tccaaatcat taagagcatg tttaatttct gttctagcct
    53161 cacctgcacg aagtattatt tgcattgcta cttctactaa ttcttcatct attatatgtt
    53221 cttcaattgt catatttata atttcctttc aatttctaaa tttaaacctc ttgactctct
    53281 aattttatct cttctttctc ataagcttta aaaaatggat accatatcat aaatagcaat
    53341 actatattta ttgctaaaac aataagacct ctaacatctt gatttaccat aaaagtagat
    53401 ataccaaaag gaacatacca taaattaaac accttacttg gaattgtaac aaatcccata
    53461 ctcattgata aataagtagt tattgatatt actactgttc ctatccacat aggtaacatt
    53521 aaaaatgggt tccatgccac tggagctcca aatattactg gttcatttat attcattata
    53581 gaagggacaa tacatgctct tcctattgct tttattcttc caactctgga taaacacatc
    53641 attataacta atggtaatgt agcacccaac cctcctaaag ttatccagcc tgtttgaata
    53701 acttcgtaaa catatatatt agttgctact cctcctgatg ctactgctgc tgcattagct
    53761 gcaattgcac caagttgaat tgaataagtt ataggagata gtacccaccc acttattcct
    53821 aaagaatata taaatactac taagaagttt aagagtacaa atccaggtaa tgtctgtgct
    53881 atatctgata ctggtttaaa tactctaact attatttcaa acatgtcaaa gttgagtcca
    53941 taaattaatc cccagcctac aaacattatc actgttatag gtaacatatt atcaaaccac
    54001 ttgcttacaa aatccggaag tgctgaatct tctccgaaaa atgaaaaaga accaaataaa
    54061 gacattatta atccagagaa taatcctgca actagcgata caagcattcc ttctcctcca
    54121 aacctgttga agttaaatat agctccttca ttcgtaatct ctggacgaat catcattaac
    54181 attaatccag cacctgcaag accagctact acactcatac tttcaaattt cttattcttc
    54241 attgtttcca taggcaataa aaatgctata aataatccta aaagtccaaa tgtatattga
    54301 tttattggac ttaaatcagg taaaaagctt atgtaattct tcaagacaga aactatagtt
    54361 actaatgagc ctacaaatac cattggcaaa actttcatta tagttgattg aactgattgt
    54421 acccatatat tcttagtcat attatttaca acaggagtaa atttttcact taaaaaatct
    54481 ataaatttat tcataaacac tctccccata aatattttat ttgtttgata ttagttctag
    54541 tgcttcttcc aaagcctttg caccatctag tcttccatat gcagttttag atatacatgc
    54601 tactggaacg ttatattcat tagccttttg ttgaatttct tccttcatat aatctaaatg
    54661 tggtcctagt aataaacaat ctatttctga taaatactta tctatctctg actcacttct
    54721 cgcttttata tctgcttcta tacctttttt ctttgcactc tttctcatac tagttgccat
    54781 aaaacctgta cttgctcctg aaccacacgc caaaagcact cttatatttt tcataataat
    54841 acctccaata tttttatcca ttaatttatt tcttaatgaa ctttttattt tattatgttt
    54901 atattttact tcccaaataa gttcatttca cataaatata tttcctaata ataggaaatc
    54961 atttactctt aattagacct attaatatag tataatgtat cttataatac gtacattcaa
    55021 ttatataatt atcatatcat acagatttta ttttaaaact atgcgaggga atctaatgaa
    55081 aacatctaaa aaagagctat ttttaaattt cataaaaacg caacatgatt ggatagattc
    55141 atccacatta gctaattacc ttaatgtatc aacacgttcg attagaaaat atgtaaacga
    55201 gattaattct aatggtgcat ttatattatc ttctaaaaag ggctataaag taaatctcaa
    55261 tactaattgt caaactaaga ttgatagttc agagaatata tcacctgata acagattaaa
    55321 tttaatttta aaagaactta tagttaatag taatggaatt aatatatttg atttaagtga
    55381 agaattattt gttagcccag ctactattga aggggatata gtcaaagcta ataaatttat
    55441 aggaagttat aatttaaaga taaagcaatc gaaattttta ttgaaactag ttggaaatga
    55501 gtctgcaaag cgcaagttaa tgagctctat aatatttaaa gaaacgggaa gtgatttttt
    55561 aagcttattt gatgtacaaa aaatatatca agagtataat ttgactaaac taaaagaaaa
    55621 tataatatat atattaaaaa aatacaattt atttataaat gagtatgcta taaacaacat
    55681 acttcttcat ttaatgataa ctatagacag aataaaaaag aataattaca tagactctgt
    55741 tgaagtagta aactacatag acaataacgt agatataaat attgcaaaag acatatcaaa
    55801 ttttttagaa tctgaataca atataacttt aactagtgcg gaattatact atttagtatt
    55861 tcagttaaca aacaaaacta cagtcttaaa ctacaatcaa atggatacta aatcattgtc
    55921 aaattatata gatgaacact ttgttaaatt aactaaaaaa ataattaaaa atgtatatga
    55981 cttatatctt atagatttat ctgatgagga atttgttgta aaatttactc ttcatgtaaa
    56041 aaatttaatc agtagagcca aaaataatca agttttaaga aatcaaatac ctcaaaagtt
    56101 aaaagattcc taccctttga tatatgatat atctgtttat atttgcaatc agattcaaac
    56161 tttagaaaat gtagatatag acgaagatga aatatcttat atatctcttc atgtaggttc
    56221 attctttgat agacaaaaat tattagaaga taaagttcta tgtgcattaa ttactccaaa
    56281 ttactatgat ttacaattca aaatagtaag agaccttgag aagagattta atgaatccat
    56341 agaaattatt cagatttttt cagatactca taatcttgat tttgacaata aggtagacat
    56401 ggttattact actttaccaa ttaacgatag atgccctata ccttttgttt atgtaaatcc
    56461 ttacctaaat agaaaggatt atgataatat tcaaagtaaa tttattcaga ttaaagatag
    56521 aaaaaatata cttactgtac aaaatcattt agaaatgtac tttagtgaat ctttgtttat
    56581 gaaaaatata tatttagata gtgctaaaga ttatataaga tttatgggaa atattctgta
    56641 cgaaaataaa tatgtcaaac ccaattatat agatgatgtt cttataagag aaaaaatgtc
    56701 ttcaactgca tttaataaca atgtagcaat tcctcatagc atgaaaatgg atgctttaaa
    56761 aaccggagta tgtttaattg ttaacgataa accagttaaa tggggtgagg aaaaagttca
    56821 aattatagct atgataccta taaatgaaaa agaaaaagaa aaattcaatt acatatttga
    56881 aagctttatt gaaatattat ctgaatggaa taatgttaaa gaacttacta aggcagataa
    56941 ctatagtagt tttatgaata gaatagctta tcttattcaa aatatctaaa tccattaatt
    57001 tatttccaat atatgtttct taagttatta acataaaata gataagctgt cacactaaaa
    57061 agtctaaatt aatatgtgac agctttttac ctaatatacc ttgttttaat actacatatt
    57121 ttttgactgt tgtatactag ttataagatt gaatatttgt gttgttgtag ctgtcatatt
    57181 ctcactagca gttgctttat ccattgcttc ttctattgtc atagctctat ttactataga
    57241 aaaataagca tctataccct cttcattaca tttaactgca tcttctgttg tggctccagc
    57301 caaacctatt acttttaccc catatttttt tgccagtttt gcaactccta ttggagcctt
    57361 gcccatagca gtttgattgt ccaatctacc ttcaccagtt atgacaaaat ctgcatcttt
    57421 taactcttcc tctaatttaa tttcttctaa tattattttt attccagatt ctaattttga
    57481 atctaaaaat gctaaaaaag caaaacctaa tcctcctgct gctcctgctc cttctacatt
    57541 agctacatct ttacttaagt aatttttaac tactttggaa aaatttctaa gcccattatc
    57601 taacttctca attatttctg atgttgcacc tttttgagac ccgtatatgt atgcagctcc
    57661 atttttccca aacagcggat tatttacatc acaggctatt ttaaacttac attcatctaa
    57721 ttcctttaat ctattttcta tttttatatg tcttatttca tttaaaactt ttccacctaa
    57781 tcctactaac ttgttatttt tatcataaaa ctcaaaccct aaggcttgaa gcatacctat
    57841 cccagcatca ttagtagcac ttccacctat cccaactata aaatttctat agcctttatt
    57901 tattgcttcc tttattattt ccccaacacc ataagttgta gtgtataaag gatttctaag
    57961 ttcagtcgga accaatgtta atcctgatgc ttgagctatt tctattattg ctgtacttgt
    58021 attttttaat aatccatatg ttgcatccac ttttttagct attggtccag taacttctat
    58081 agtctctttt ttaccattca tcccttgaac taaagcatct actgtccctt caccaccatc
    58141 agcaagtggc aatatcttta cttgcgcatc ttctttaacc ttcaatatcc ccttttttat
    58201 tgcatttcct gcctctattg aagataagct tcctttcaaa gaatctatag aaattaatat
    58261 tttcatactt atctactcct ttttattact ccttatttta aacatataat tttataagct
    58321 taatttatct tttattttat actctacatc tctctttgta tacaacttat accattaata
    58381 ttcttttatc ttataaaaag ggagtgtctc aaaataaatt tcttagttca tgagacactc
    58441 ttttgtataa aatcaaatat atgtttatta tttcaacaat gataaggagg attatctcta
    58501 ttttaagata attccttttt agcactatct aatcattttt agcactattt aaccagtata
    58561 gttttaactt ggttcattaa gcactctaca tttacagagt tattatctat tgatatagat
    58621 tctaattctt tttcatttag gttaatccat ttagctgttt taatattttt gttaaatact
    58681 atgttagctg attttgtttc ttctttagaa ttataaaatc taactactaa tgcctcttct
    58741 ttttcagcct tttttacaac acttaacaca aggtccttat tagtttcctt aagtaaacta
    58801 tatgaataat ctacttctat ttctgattga ttcaatttca tagcattata tggcatttta
    58861 ttataagttt gtatttttgt taaatactct ttagccatat ttgcaacatt tgcttctagt
    58921 gtagattttt catgagtaac tattgctaag tctattttta tatctcctat catttgagaa
    58981 tctggagtag gcaactttat tcctgatgga cgacctgggc gtcttgccat ttcttcttta
    59041 cctaggaatc ctacacttct aaataatgtt atagctattg tgtcaaattt ttcccctact
    59101 atttcaaact ctcttgtact gtttgtaaga acagctactc catgctcttt gtcagacaat
    59161 ccaacgaatg ttagcattgg atatatagaa tctggtcttt cactccagtc ttcctgttgc
    59221 caaacttcca tagcatcatc atacacactt ctctttatat gtccaaactg attatcagac
    59281 acagaaaact ttgaagctat atttgttggt atataagttc taaccctaca atctcttgct
    59341 tggttattta tgttgaatac tacatctatt atagctttat catttggaac atttataact
    59401 atatcaaagt caataaatga atctgctcta ttattttttc tagcttgtat atcttttggt
    59461 acttttaatc tataatttat ctttatctca ttattaaatc tatttttctt tatagtggaa
    59521 tttgctacta tattatcgtt aaatattaat ttctcatttg gaagtggtga aaaatcatac
    59581 tcatctcctt catctcctcc attttccatc aataatacat tttcaaaagt tttatttaat
    59641 tttttatcaa atatctttaa tgtcccgttt tcattaactt gaatagtata aaagtcatta
    59701 tctaccatgt cacatacttc ataagctttt tctaacatat gttcaacttc ttttatcata
    59761 tacgccttat accccattgc aggtatttta tctttaaagt ttattgtata taccataaat
    59821 gaatcatagt ttccataatg aacaatttga cggtctatta atcctgcatc tattacttct
    59881 ttatgtacca cttcaaaatc caacttatta ttatctttat caaatatttc aaatgctttc
    59941 attttagtta taacttgggc gctcactatt tcattcctat cgtaaggcat taagttaaat
    60001 gctattaact tatctaaagc catttcacaa ctcattgcat caactattct tcttttgtaa
    60061 aatgttatta attggtctac tttttcctca gctaagaaaa atctattcat tatttcctgg
    60121 tgaactttat ctgaacaaca acatccaatg ctgtcatgag catgattttt cattatttct
    60181 ttccaaatta actctattaa tccatgatga tattcaaatc ctagagaata tgcaatagaa
    60241 gctagtggct ccaatatgtt agttatcttt gattctattc tagcatttgc tgattttata
    60301 tccattcttg ttgagaatat acttctatga accctcatat atttcccatc taaaaattcc
    60361 ccttttattg tatctatatc ctcatttttt tctagctctt taaatatgtt ttcatatcta
    60421 cttaagaaaa attttctgtc tggataacat tcttttaatt tatatataac ttcaaatata
    60481 ttcttttgaa ttggcatttg gtcatgtcca tttggaagta ttatatggtc agtagttgca
    60541 cccttatcaa gaaccggtaa atatttatcc attcttgttc ttagctcatc ttcattcatt
    60601 ggtagatatt ttcctattgc ataacctaat ggaagtattt gaaccaaaac agaagaccca
    60661 tcatcactct tccaattaaa ctctgtttta ttagttcctt ttctttcaga acatcctctc
    60721 caaaacattg aatattttat atcaaaccca tttagtattt gtggcatttg agcactttga
    60781 ccaaatgaat ctggtaaata tcctattttc atatattctc caaattcatc acaatctttt
    60841 attccatata gtaaatttct aagtatggat tctccaccaa ctaccatttc atcagtttga
    60901 gtataccaag gacctattat tagccttcct tcttgaacta atttttttat tctctcctta
    60961 cattcaggct taactgctaa ataatcttct aatatagcag tttgaccatc catcacataa
    61021 tatggatagt tatgattatt ttctaacata tccattattt cttccatatt atttacaagt
    61081 aatattctag attcctcagt tgagaagtac cattctctat cccaatgcat atgaggaact
    61141 atgtgtacat tttttttcat tgcttatcct ccaaaactta tctgataata ttttctgtct
    61201 aattaaaaat ccaataaaaa tactactgag tttacaaaat tttttaatat ttattttatc
    61261 actataatta aacctttgat ttaaatatct aataacgtat cttttaatgt atctttcttt
    61321 gatttttttg tttcctagtt attattaata atattgctga tattatagct ccaagtactg
    61381 ccgcaaagaa ccatattgat gctataataa atcctgacat acttccctct aaaagcgcca
    61441 atgagaatat ccccgctcca ggcacttgaa gacctatatt gaagaatgct actatagacc
    61501 cagttatggc tgaaccagct accaatgatg gtataacacg gattgggtcc tctatcataa
    61561 atggtattgc accttcagtt attccagcca atcctaatat ccaagtttgc tttcctattt
    61621 ccttttctga ttctgaaaat aaatctctgc ctaaaacagt agctattgta actccaaaag
    61681 ctgaaaccat cttaactgat gcaaatattg cataaggtat aaaatttcca cttgctattg
    61741 ctcctattgc aaatgtatag gctgctttat ttattggtcc acctaagtca aatgaaacca
    61801 tagctcctat tattgcacct agtagtattg catttactcc agtcatccca tttaaccaat
    61861 ttataagacc attgttaagt gctgctacag gctttcctac tacaaataac atcaataaac
    61921 ctactaccaa agaaccaact actggatata cccaaaaact tacgaatcca gctaatgtgc
    61981 ctttggctgg tatattcttc tttaaaaatt ttactatata accagcaagt aaacctccta
    62041 acatacctcc aagaaatcca ctacctatta aatcagctgc tagacctgct gcaaatcctg
    62101 gtccaagacc tggtttttca gctagtgagt aagacatata tgctgataat actggaacca
    62161 tcaatgtacc taacatacct ccagaaagct ttcttaattg ccataaccaa gaaccttctt
    62221 gattgtatag ttcttgtaga ccaaatgctt gagatgctaa tactgcaaat gcaagtatca
    62281 tacctcctgc cacaataagt ggtattatat gagatactcc tgtaagtatt gctgatttta
    62341 catctttttt ccatgatgat ttttcacaat atgatatatc agatgatttt tctatataat
    62401 cacctttacc ttgtttttgt gctacttcta aagcttcgta tattatttct tttgctcttt
    62461 ttagtggagc tgctactgac gtttttatgt ttggcaaatg ttcaaatctt tctgtatttt
    62521 taggtgctac atctgttgca tatattattg catctgccct ttttattata tctggcgtat
    62581 gagggtccac cataccatta gctccttgct tttctacata cacatccaca cctatttctt
    62641 taccagcttt aattaatgct tctgctgaca tatatgtatg tgctataccg gcagggcatg
    62701 ctgttattgc taatataatt ttttttgatt cattttgaat cctaatctct tcttttattt
    62761 gttctttctt ttcttttata tctaagttat taaataactc tttcttagtt tttgaattta
    62821 acaacatatt catataatct tcatttgaca gtctagtaac taactcagaa agtatttgta
    62881 tgtgtgtatt tccaccttca ctttctggta ctgctattaa aaatattagc tctactttat
    62941 tatttgggtc tacgctttcc caattttcta ttggtgtctc taaggtcata gctgcaaatg
    63001 cagcttcttt aactgactta gattttccat gaggaattgc aagccctctt tcaaaacctg
    63061 ttggagataa agtttctctg tacattacag cttctaaata ttcctcataa gatgttaact
    63121 tgccttcatc atatagcttt cttgctaaga actttattgc gtcttccttt gtttttattt
    63181 tttgttttaa aaaaacaagg ttttcatttg tgattttctt aaattccaaa attacgccct
    63241 ccttaaatca tttaatgcta tgaatatagc ataaaataaa ttatgaaaat gtttttttga
    63301 aattatacac acaatttctt cttaaaaaat aaagatttgt gtatttatac acaaatctct
    63361 atcttaacca atattgctct attattgctc tcataatcat cataattgga accttatctg
    63421 atatattgta cccatttact tgtttaattg ttgaatagca atataaactt atatctgcaa
    63481 tttgttgcaa ttgattttca catatatgtg ttaaagctac taccttacaa cccttattaa
    63541 ctgctgtctt tgctgcttct ataacttctt tcgtttctcc acttaaacta agtgcaaaaa
    63601 acatatcttg ttcacctaat tttcctatat catgaagtac ttcatgtctt tgactatagt
    63661 aagttatatt atcatgccca cctctaattt cttttactaa tatctcacat aaaggaatgt
    63721 tttgacctat tccataaact ataatactcc tagatttttg aattatatct gctactttat
    63781 ttattttttc ataatctatt agctctaatg tcttttttat atctgattca aaaccatttt
    63841 ttggctcttt atcctcattt tttaactctt cttttaaatt attttttagt tgagagaaac
    63901 catcatactc cattttttta catagcctaa ctatggtatt tgggacagta aaaaatttat
    63961 ctgctaaaga ttgtattgat aattttacta tttcttcttt gttttttctc atatattcaa
    64021 ttatcatgtc ttctgtatct gtaaatttat actcatattt ttttgctctt tcataaaatt
    64081 ccatagtttc tcctccatct attttattat tcataagtaa aattcaaaaa tattagctaa
    64141 aattttcgtt aatataatta taatttaata tttttaattt attaatgcat actactcttt
    64201 ttattataca taaaaaatgt gtacttccta tattgataga gatgattcaa gtttttattt
    64261 tgatacatct ctatcaatat ttttttagaa aatacacatt tttttcaaat acttattttt
    64321 aattaaaact ttaggtaatc tattctttat atataattat tagacttgaa aatatcttta
    64381 aaatcaacca attcaatatt atttcttttt aaccacattt taacttcctt atcacatagc
    64441 attgcatgtt catatactct ctcttgaata agagaagatg attttataag actataatct
    64501 ataaatcctg gatgagtaac catcaatgtt atatctttat ctaaatttat atatttttct
    64561 tcaaataatt taacaaaaga tttatttaac ttgtaaaaat cattctgagg atatttactt
    64621 ggcatgctaa tacatgaatc caaataatag ggacaacttg gtataccgta ttcttttgca
    64681 gcatcacaca ttgctgatat tgatacatct tcttctatac catgtatatc aatatactca
    64741 ggcaatttac tcatatacaa cttgtaagtt tcaatttgag cacaaacttc ttcatatact
    64801 tcttcataat taaaaacctc tttacctgtc agtagttgcg ttcttcttat tttgctagaa
    64861 acaaattttc caccttcatc taacaaattc tttatcttaa tatgttcttt gcaacaaggt
    64921 tctcctatta ctaaattaac atgtaaacca aaacatacat catcattttt taccatttct
    64981 atagcttgtc ttgaaaaagg catattcacc atgattccag cacttgtaac aataccgttc
    65041 ttataagaag atattatccc tagtgtaaca ccttctgaat atcctatatc atctgcccta
    65101 actactaatt tcttcatttt atgcatctgc ctgctttctc aactcatcaa gttgcatttc
    65161 catctcatcc tttactttaa caacatccgt tcctatgatg atttgaactg atgtattact
    65221 caatttaatt acccctttgg ctcctgtttt tttaatatta tcatcattca aaatagtggc
    65281 atccttcact tctaaacgta atctcgtcat acaattatta agagtcacta tattttcata
    65341 accaccacaa tttttaatta tctgtttagc catatatgaa aaattaccat gagaaagttt
    65401 taaattcttt tctttttcac taactttatc acctatctct atctcaactt cacgtcctgg
    65461 tgtttgcaca ttatctttta ttattatata tttaaatgtt acataatata atacaaagaa
    65521 tacaactcct acaggtataa ctaaccacgc tttatctcca taactaaaac ttaagacata
    65581 gtcaattata cttgctccat taaatgaacc caagcgagca cccaataaat atagtacaac
    65641 tccacctaga ccagaataaa aagaatgaat tatatataac tttggagatg caaataaaaa
    65701 cgaaaattct attggttcag ttactgttgc cataaaagaa gtcaatgctc cagcggtcat
    65761 tgcacctttt acttcttgct tctttttatc ttgtgctgtt ttatatatag cataagaaat
    65821 agcaggtatt gaaaacatca taattatgta aaatcctgtc cagaagaatc ctgcatttgg
    65881 gtctcctgcc ataaatctag gaatttctcc tcttataact tctcctgttg atgttgtata
    65941 ttcacccatt tcaaataata tgtaagcatt taaaacttga tgtaacccag ttggtattag
    66001 tgcacggtta cagaataaaa acaagaatat tcctattgca ccagctcctc ccaaccaaaa
    66061 accaaattga ttcattgcag cttgtggata tatccataat aaactaaata tatatgataa
    66121 aattaaagca accactggtg atagtgtaat tacacatttt tctcctgcaa agaagcttaa
    66181 aaatgctgga actttaactt tatatgtttt attgtaagtc catgctatac aagctccaac
    66241 aattatccca ccaaatacac ctgcatttaa tgtatcattc aataactcta aatttgactt
    66301 aaatatcata tatgcaacta cggctgcaac cattacactt gtcttgtctt tagactttga
    66361 gtaggcacta gctgctccta ataaaaataa gtagtccaca tttgaaaata ctatattaga
    66421 tatattagat atagctggca cattgagcat atttggacca aataataatc ctaatatacc
    66481 tgctgctggc attacagcta ttggcaccag catagtcttt cctaaaagtg acagttgttg
    66541 catcattttg tttaagaatc tcttcatatc caatcccctt tctatttcgg tttaattttt
    66601 tgtgaaaacg atttattcac attttatatt ttaaatatta tatttgttta aacaaattgt
    66661 caatattttt tattcatttt atttttatca tttagtttaa catataaatc cttttaagtg
    66721 tattgctata tctagtctat ttttttaatt catttttttt attttaaaaa tatgtttaac
    66781 catgtatttg aaacaaccca caaaataatt ctattttgtc ctttttatgg ttgatatgat
    66841 tctattttca ctatacatgt ctaaacacat ttgatataat ttgttcatat cagttcaata
    66901 atattactaa agacctttaa ggagggatag gggtatatgg ctaaaaataa attttcagag
    66961 atatatgaag tattgaaaga ggaaatactt gatggtaaat atacaagtaa tatgatgctg
    67021 cctactgaac ttcaacttat tgaaaggttt tcatgtagca gaaacactgt acgtagagca
    67081 atttctcaat taaacacaga aggatatgtt caaagtataa aaggcaaggg tgttgtagtg
    67141 ttagaaaata gttgttctaa tgattttttt ctaaatatgc acaatttcaa aggtgtagaa
    67201 tcgattgtag aagataaaaa ggttaatact gctactagtg ttctccactt cagcaaaatc
    67261 ttaattgata ataagttatc taaaaagaca ggttttaaag ttggtagtga agtatattac
    67321 cttcacagac taagatatat tgataacata cctaaaattc tcgacattaa ctattttcta
    67381 tgtagtatag ttaaagacct tgatgtttct atagcacaag gctctattta taaatatata
    67441 gaagagtgtc taggtacaaa aattgtttca tcaagaaaga tatttaaaat tgaaaaagct
    67501 acagaacttg agttaaaaac gctacctcta aatgattata attgtgttgg tgttattaaa
    67561 aatagtgtat atactgatga tggaaagctt tttgaatata ctgaatcaaa gcatacacct
    67621 gaaacatttg tattcatgga tgttactcaa agatattaaa aaaattatgt ttaattaaac
    67681 ataatttttt tacgtttaga cactttatcc catactaacc tcactattct atatacaatt
    67741 atatgtttat acaaataatt atttattgta tattttagct ttaatattag tttaacgctt
    67801 gacaatttgt ttaaacatat tataattaac ttataaatta caggaggtat caagtatgaa
    67861 aaattggtgg aaaaaagcaa ctgtctatca aatatatcca aaaagtttca aagatagcaa
    67921 caatgatggt ataggtgata taaatggtat tatagaaaaa ttagattatc tgtattcttt
    67981 aggtgttgat ttattatggt tgactcctat gtacgtttct cctcaaagag ataatggata
    68041 tgatatagaa gattattata atatagaccc aaaatatggg acaatgagtg actttgaaaa
    68101 actcttaaaa gaagctcata aaagagacat aaaaataatg atggatatgg tcctaaacca
    68161 tacatctact gaacataaat ggtttaaaga atctaaaaaa agcaaagaca atccatatcg
    68221 tgattattat ttctggaaag atgctaaacc tgatggttct gttcctaata actggatatc
    68281 cagatttagt ggaactgctt ggaaatatga tgaaaccact aaccaatatt atttacattt
    68341 atttgaagaa actcaagctg atttaaattg ggaaaatgaa aaggttcgtg aagaatgtta
    68401 caaaatacta gaattttggg ctgataaagg tattgatggt tttcgtttag atgtagtcaa
    68461 cctactctcc aaaacacctg gattacctga tgaccctata acaggaccaa aaggagatgg
    68521 aagaactcac tacgctgatg gtcctcgtat acacgaatat ttacataata tgaatcaaaa
    68581 agttttcaaa cctaaaaata tagttactgt aggtgaaatg tcatctacta cacctgaaga
    68641 gtgtatcaac tatactagag aaaatcgaga agaactatct atggttttta gcttccatca
    68701 tatgaaaaca gattataaag gaggcgcaaa atggactaat gaaatgttct ctctggataa
    68761 attaaaaaaa gcacaatctg actttcaata taaaatgtat gaaggaaaag gatggaatgc
    68821 tctattttac tctaatcacg accaacctag agctttatct agatttggag atgatagatt
    68881 ttttcgtcaa gaaagtgcta agatgttagc cataacatta tttggtctac agggtactac
    68941 atacatatat caaggtgaag aaataggtat gacaaatgcc tactttacta aaatagatga
    69001 atatgatgat gctgaaagta agaatgcata ctatcatatg attaaatctg gtattgatga
    69061 aaaggaggca ttgcttatac ttcaacaaaa atccagagat aatgcccgta ctcctatgca
    69121 atgggataat actatttata aggggttttc taatcataaa ccgtggttaa aagttaataa
    69181 tgacaatatt agtgtagaaa atgagcttaa tgattctcgt tcagtatttt atacttatca
    69241 aagattaatc aaatatcgta aacaatatga tatttttaca gaaggtactt atagattgtt
    69301 agatgaaaat cataaaaatc tatttgttta tgaaagagag tataaaaacc aaaatcttct
    69361 tgttataagt aattttactc atgataatgt agtatataaa ttacctgaaa cttatttgaa
    69421 taaattaaac tacacaatac ttgaaaccaa ttacactaga gatataattg aaaataaaat
    69481 ggaaataaaa ccttacgaaa gtataatgat atattataaa taaagttatt tatgtaaaaa
    69541 tcggtataac accctggtgt tataccaatt ttactaaatt caaagtaata tttatagaat
    69601 atctatagat tacaataatt atttgacttc tacatcatta tatttctttg aatatacttt
    69661 agtcatatag aaatatatag gaactacaat tatcatccca cctaatcccc aaactatctt
    69721 cataggttca tcaatacctg cttttatcag taataatata cttataataa ctgcaaatat
    69781 tggtataatt gctcctccag gtattctaaa atttacatct ttaccagcat acttctttct
    69841 caatattagt acagctaaac atgtaggaat atattgaata aatctagata caacacttat
    69901 ttgagataat gttgtgaatg aacccgacca tgctattagt aaagttccta tgacagatac
    69961 tataattgct atataaggag ctccattttt attagttttt cttatagact taggcattaa
    70021 tccttgttca accaaagcag cagcagacct tggtgtaaat atggatgatg caatatttat
    70081 acctccaaca gatactatag ttcctattgt aattatatac ccacctatag gacctaacat
    70141 cttaatggca gcatctgcaa caggagtagc tgaccctgct aagccattac ccaacacccc
    70201 tatacttatt cccagtataa gcatatatat tactgatact acaaacatta ccattaccaa
    70261 tgctttaggt acatttttct tagggttctc catatctttt gctgcaacag ctaaagattc
    70321 aaatcctgta aaagcataaa ataaagttat agatactgct acaaaagctg atgacgcact
    70381 ttgacctttt tgtattatta caaatggggt aaaattagaa ccctttataa agaataatcc
    70441 tacagctata aataaaacta ttggtaataa ttttcctata gtcatgatat tatttaagtg
    70501 cttagattgt ttcatcccca taaaatttat aatcccaagt cctacaacta atataccaat
    70561 tattatattt ttagtaagtg gttctgctgc ttgtggccat acagatgata gtgttacagc
    70621 aaagaaattt gccatagtag cccaagcaat catactaact atccacttca taaatccaac
    70681 ttcaaatcca acaaaatctc caaatgcctc ttttgcataa agatagggcc ctccatcagt
    70741 atcaaaccaa ctacctgctt cagcaaaaca taaagcaata gaaacagcta aaagcataca
    70801 aaaaactaat actaatatac ttgctggacc tatatctgta taagcatcac caggtaaccc
    70861 gaatatacct gaccctatta ttgcattgat tcctaatagt acaatactcc aaaaacctaa
    70921 cttaatgcct ttttccattg ttattccccc caaagccaac ttaatatatt tgtatttttt
    70981 atttagatgc ttctttaact attgccataa atattttttt catattatca taatccctag
    71041 tcatcatttc tggatgccat tgtatcccta ttacaaactc acttccttcc ttttctatag
    71101 cttcaattaa accgtcttta gatgtagctg aaacaatata tcccggtgct actttgttga
    71161 caactaagtg atgaaaacta ttaactaaaa cttctttttc tcctaatatt tcatataatt
    71221 ttgtcccctc ctttatctgt actgtatgtg taggtacatt agatagatgt tgctgattgt
    71281 gtttaatata agcaccttca attaaagata aatcttgata caaactacct ccttcagtta
    71341 catttataat ttgttctcct ctacatatac ctaaaactgg ttttttcata tctaaagcat
    71401 gttttaataa tttcatatca aaactatctc tctttggtga tattgccccc aacttattat
    71461 gaggttcttc tttccatatg agtggattta catcttgtcc cccagatagt ataagcgcat
    71521 ctatattaga tacctgctcc tttataatct catcatcata tacaatcggt acaatatatg
    71581 gtatagcttt acacataact actgattgta tataatcatt atttacataa gccctttcat
    71641 agccaggaaa cattcctcct tcatcaatta gtaaattacc tgatattcct attattggat
    71701 atttcttttt agccaatttc ttcacccctt aacttatttg tgaacaataa aaaatgctac
    71761 ttctcttaaa gagcaagtag cataccaaga ttttatttat ttgaacatta taatttattt
    71821 tagaaatact ttttttgaat acgagtaata taaataactt tatttactta tattttattt
    71881 taatcctgtt tagtttgact tttttaaatt gttttaagta caactaatag gtaaaatagg
    71941 catttagatt ttccttttta tcaacctatt aaatactgtt taatatattt tttccccttc
    72001 tatttaattc acttcccttt ctaccagatt cacatattat caaatccagc tcttttaaca
    72061 tattaagtat tccccttacc tcaccttctg ttatattgta gcctaattca tttattgaat
    72121 taacaatacc atttctacct atatttttat taagattatt ggcatttttt aaacactcca
    72181 ttactaactt tactttctct atagatgttc tatcctttaa tatacttatt tctttactaa
    72241 aatcttcagt tatatttaat aagttatgag gtaaatcatt tattaaaata acatcctcag
    72301 aactcataat gttaatatac atagcagtat tttttaattc tcttatatta cctggccatt
    72361 catatgcatt aataatgtct tgaacatctt gactaattgc tctcttcctt ttcataaaat
    72421 gctttaacat aacttctata tcttcttttc gctctcttaa aggtggtata tttatgggca
    72481 atacatttat cctatagtat aaatctgctc taaatctatc tccttttatc atttctaata
    72541 aatttttatt tgtagccgca attactctaa catctatatc tattacattt tctcctccaa
    72601 ccctcattac ttgattctct tgtaatactc taagtaattt gctttgtaag tatataggca
    72661 tgtctcctat ttcatccaaa aatatagttc cattgttagc ctgttcaaat aatccttttt
    72721 tacctccttt taaagctcct gtaaaagcac cttcttcata tccaaaaagt tcactttcaa
    72781 gtaaattttc tggcatagct gcacagttta tcgctataaa tggctgacta tgtcttggtg
    72841 atgcattatg aatagactga gccatgagtt cttttcccgt tccactttct cccgttataa
    72901 gaattgtata atcagattca gctattttca tacctaattt cttagttctt tccatcttcg
    72961 ttgaaactgt ttttatatca tcaaaagtat atctagcaac ttgtcccttt tctctaagct
    73021 tctttgatag gttttgctcc aattttctta tgtaagttat ttcttgaata caaaaataat
    73081 atccagtaac ccttccaaaa ctctctatat tatacttatt tacgtttaag tacttattat
    73141 taaattttat aacttcatca tgtgccttac tcaaactaaa aatcttttta atattctcat
    73201 tctctaattc atctatattt ttccctataa tattactttg aatatctagt atatccccta
    73261 aactattatt gcaaataatt atgtttccct tatctgatac cattgccata cctaagtttg
    73321 ataaatttat tatagaattt aattcatctg cttttatagt aagttcttta tatttagtat
    73381 ttattcctga atataaacta attatttcat ctgtatactt aattagcctt tcagtaattt
    73441 ctttatcatc cagtttgagt tttgctatta tttgaataaa cgttgaacta tcaatatacc
    73501 tatggcctaa atcaataact tcttctatat attttggaac taaacttgcc tctcctggcg
    73561 ttatagctat cttaatattt ctatattctt cattgggatt gtatggtata aaattcagat
    73621 gatttattcc tatattgtat aaattagata ttgtttccaa tacagtatgc ttattatcgt
    73681 ttactactaa tacatctatt ccttctggca atgaaaataa cttatatata tccttttgct
    73741 ttatgctcct atttatagtt attatctttg agacatcttc tacatatttt tttattttta
    73801 atactctatc atctatcatt accaatatta tgtcatcttt tattaattcc ttctctgtta
    73861 ttttatttaa ataataattt tttatcatta ctttatcttt aaatatcatt tctagatttt
    73921 tatttaagaa acattctaat ttagacaacc catcagttac tactgctatt gttttcattt
    73981 gattactcct tttaaaatat actctactct tttataatat acatctgatt ttcactttaa
    74041 cagcacaaaa aattgtacat ttagtatact aacatattcc tttattagtt ttatgtccct
    74101 aaatatcata gttgcaatat ctatcatatt tcttaaactt ctataaagca aaaattgtgc
    74161 caaattaata attttcttaa ttttattcta aagttcctca atagtattta cagacttagc
    74221 acttatagct tataagtctt tatattatta atctattttt ataggttaat tgtacaaatc
    74281 atatatcact tttacccatt aaatgcatta taaaaaagat ggaataacga ttcgtcactc
    74341 cacctttttt gtaataaaaa attgtatata taaacactat ttactactct tctaagtaca
    74401 aacattatct acatactata acctttcacc attagattct attacttgtt tataccagtc
    74461 aaaactcttt ttcttaatcc tagacaagtc tccacttcca tcatcatact tatccacgta
    74521 tataaaccca tatctcttgg ccatctcacc agtagatgca cttactaaat ctatacatcc
    74581 ccacggagta tatccaaata aatcaacacc atcttctaca gcttccttca tttgctctat
    74641 atgtgctttt aaatactcta tacgatagtc atcatttatc actccattag attctttttt
    74701 atcataagct cctaaaccat tttcaactac catcataggt attctatatc tatcataaat
    74761 ttcatttagt gcatatctaa gcccttcagg gtctatttgc catccccatt cactagactt
    74821 aagatatgga tttttcactc cacctaatat gttgccactt gtattatctt ctttagaatc
    74881 actacttaca catgtagaca tataataact aaatgtataa aaatctacac aaccttcttt
    74941 taaaatttct aaatctcctt tttccatttt tatttcaata ttattttctc caaaatatct
    75001 attcatataa gttggatatt cgccacgcac ttgtacatct ccacagaaat aattcattac
    75061 tctactatct ctttgagttt taactgcatc atctggatta caagtataag gatacattgt
    75121 tgcaaatatt tgcatacatc caacttgata atttgaatct atttcatgag ctaacttaac
    75181 agccttagca cttgctacaa attgatgatg taacccttga aaacgaagtt gaggtatatc
    75241 tacttggttt ataaaatctg tagtcccttc atttaatatt ccttgtgata agtagcctcc
    75301 cataggcatt gtagctgaat ttatttcatt aaatgtcagc caatatttta cttttccttt
    75361 atatctttta aatattgttt cacagtaatt catatacaag tctattacat ctcttgaaac
    75421 ccatccattg tatttctctg ttattgcaaa tggtatttca tagtgagata ttgttattaa
    75481 tggttctata ttatatttta aacattcatc tatcacattt tcataaaatt taagtcctgc
    75541 ttcatttggt tctttctcca ttccagttgg aaatattcta gtccatgcta ttgaaaatct
    75601 aaatacctta aatcccattt ctgcaaataa agctatatct tctttgtatc tgtgataaaa
    75661 atctattgct tcatgacttg gataaaatgt tcctttttct ataactctcg ttattctttt
    75721 acttactttt tgagaacctc cagtacacat atctgaacaa gaaggacctt tcccatctaa
    75781 attccatgct ccttcacatt gatttgctgc tgttgctcca ccccataaaa aatcttttct
    75841 aagtgccata attctacctc caataattta tttatagtaa ctttatttta aaataaaaat
    75901 acatatatat aattcttaat taatagaact ctcttttacg ctaaaacagt tatcaattcc
    75961 tgactattat ttacatgctt ttgtgtattt tctaaaatat ccacataatc agaataatta
    76021 gtaacaacta ctggtgtttc taagcaatat ccttcttttg aaatactttc tatgtcaaaa
    76081 gttattaata tctgaccttt tttaatctta tccccttgat taacaaaaga tttgaaatat
    76141 ttaccttcca actgaatagt atttaaccct atatgtatca atagttcaca accattatca
    76201 gatataattc ctattgcatg ttttgttgga aataaagtca ttacagtccc atcaaatggt
    76261 gccactactt ttccttcttt aggtgttatt gctacacctt ttcccaatat acctgttgaa
    76321 aacgctgcat cttgtatctg ctccaaagcc tttacttcac cttttattgg gctatatact
    76381 acttctcttt tgtttttttc tataacgcct tgcccattat catctttaga aatttctact
    76441 atagcatcat ctttccaaaa aaataatgtt aaaacaaatc ctactacaat agctactatt
    76501 attgctatta tagttgcata aacacctttc atatctccag ttgttggatt tatataatta
    76561 ggtataccaa atattccaag tccacccatt acataacttt ttacattcat tatccccatt
    76621 acagctcctg ccacaccacc acctacacag ctatatatga atggtgtttt tcttggtaaa
    76681 gttattccat atattgcagg ctctgttaca ccacatatcc ctgaaataac tgcaggtata
    76741 cacagctctt ttatcttctt atcttttaat ttaaagtaca ttgctgctac tactgctgtt
    76801 tgtgcaaaag atggtacaaa tgctcccact aatattgtgt caaaccccat agtcataagg
    76861 tttgacatag ctattggtac taatccccaa tgtagaccaa atattacaag cacttgccac
    76921 aataaaccag ttaatgcacc acataaaatt ggtgaaaagt taaataaagc taaaaatcca
    76981 tttccaacta tattagaagc ataggtagct ataggcccta taaccataaa tcccaatggt
    77041 aaagaaacta ataaaactgc cattggtaca aagaaattct ttactacatc tggtattatt
    77101 ttagcaaaca ctttctccaa cttagctgct aataatacta ttaaaattac tggtactact
    77161 gttgaagtgt agttcattgc tattactggt aatcctaaga aagttatata tactggtgat
    77221 tcaaatattg ttccagtaaa tagattgtat aaaggttgac ctgtagatgc tagagtatct
    77281 aattgaatac ctgaatagca taaaactgca cctataagca ttccaataaa tggttttaat
    77341 ttgaatttct tagcagctgt atatccaaga attattggca tatactggaa cattgcatct
    77401 ccaattgcat ttaacataat atatgcacca tcagtttctc catacaaacc caatgctgta
    77461 aatactgcat taaatccttt tatcatacca gcagcacaca gaactcctaa tattggttga
    77521 aaaactcctg atattatgtc tataaactta ttaagtaatc cttttggcgc atctgagtct
    77581 gaattatcta ttgtatctcc tcctaatcca gccaaatcgc acacaacttc ataaacatct
    77641 ggaacatgat taccaataac tacttggtat tgacctgcac ttttcattac agtaactata
    77701 ccatccattt tttttagcac atcatcattt gctattgact catcttttaa tttaaaacgt
    77761 agcctcgtta tacagtgaga taaactgcta atattatcct ttcctcctac attcgcaatg
    77821 atttcttttg atagttgttc atactttctc attttttctc ctccattttc tttttgaaat
    77881 atgaaggttt ggccaactta atgtcaccac ccaatatata taaacctaat tattaggatt
    77941 tatatctgac ttaatacttt tacttaccac tctttcaacg tgaatagtta agtataattt
    78001 ttcctcatct gttaaatcgt agttgtattt tttatgtata aattcatcca acttttctat
    78061 gaatttataa gcatttttat atttaacttt tattacattt aataaatcat cttcattatt
    78121 ttcatgtaaa ttattactaa caattcgttc tgcaaaatac tttaagtgag taataaatct
    78181 atgataataa actgaatctt catcaaatac tattctgtaa tggtatttaa ccatatttga
    78241 aatttcttgt attatttgtg taatctcata tatagttttt atactttgat ccatttgtgc
    78301 attaactata tgcagtgcta taaatccagc ttcatcttct gatagtctaa tttcaaattt
    78361 tttttctata taatccaatg cctctaaccc tattttaaat tcactcttat aaaatctttt
    78421 tatatcccaa agtaatacat tttttacact tactccttca cgagctcttt ctattgcagt
    78481 atacatatgg tctgttaaag aaatataaat actatcattt aatcttttcc ctagtttttc
    78541 tttagcatat aaaattattt catctgataa ttccatatat cttataggaa tatctgctat
    78601 tagttcttta aatttatcag atatatttgg gtctgaaagt ttgaatatct tatcaatttt
    78661 atcctttgat atatgctctc ctgtacgttt tttataagct aaacctctcc ccataactac
    78721 tatttcctta tgattttcat cagttgtaat aattacatta ttattgagta ttttttcaat
    78781 aatcattgtg atgccccctt tattagcatt aagttaaaat aaatcttttt taattattta
    78841 gaatatttaa aatgtaattt attacataaa aaaaaaccta tttattacac attaaataga
    78901 ctcccatgag tcctgagtaa taaataggtt tagcttgtat ttaaacaatc actatccgtt
    78961 tgtattttat tttaattatt atttattata tgttagcaaa tttatttttt agtgtcaact
    79021 ttttctcaat attttaattt taaataaatt atataaattg aatcttcaaa gtactatttt
    79081 tatcaataaa caaaataaaa aaggtattac tttctttaag taatacccat ttatttttaa
    79141 tttaagtggt ttttcttaat ctcatcaagt agtccatctt ctaaataaat ttctaatgca
    79201 catcctacca ttgcctttac tgctttgtga agtttatcat aagcttcctc agaatttgca
    79261 taatttagaa attctttttc atgaacatat accattggac ttatatctaa ggctatttct
    79321 gtatacatag tagggcaaac ttgacttaca ttacctatat ctgtagaacc tactggacca
    79381 tctttacctt ctaatatatc tgttatacct gcctcaatca aattattctt tgttatcttt
    79441 tgaagtactt tgttatttat tatgttgtca aaagaatttt caaagtatct ataagaaagc
    79501 ttagctcctg tcattaactc tgcacctttt gcacagttta taactttttt agttacttca
    79561 tctaaataac ttctttcagc agctcttacg aaaaacttac aagctgcttt ttctggaact
    79621 atatttggag cctctcctcc atttgaaact ataccatgta ttctaacatc tgattttaca
    79681 tgttgtctta gtgcatttat cccagcaaaa gtaagttgta ctgcatctag tgcattgact
    79741 cccatatgag ggtgactagc tgcatgtgct gatacccctt caaaactaaa ctctaatgaa
    79801 tctatcgcca aagccttaca gtttatatta ttaaaagctt ctatatgcat ttgataactt
    79861 acatcaacat catcaaaagc tcctgcctta actaaatcac attttcctcc tgttgtttct
    79921 tcagctggtg ttcctattag tacaattttt cctttaaaat tttcttttaa cttacttaat
    79981 actatacaag ctcctagtgt agatgctgca atccagttat gtccacaagc atgagctggt
    80041 tctttatttt ctccatatcc aggaagtgca tcatactcag ctaaaaatgc tatggtaggt
    80101 ccatcattat ctcctaattc agctctaaaa gcagtctcca tattacaata tggataaact
    80161 gtatcaaatc catattcctt cattttttct actaagtatt ttgatgatat gtattcttct
    80221 tcccctaatt caggattgtt aaatataaaa ttacaaactt cttcaatttc ttttccaagt
    80281 tcattctcta tctcataagc tctcttcttt atactctcta tcataattta cctcctacta
    80341 gaatcctaga tataatccta ttgtcaaaaa tgcaattaca agaattgtta atactaccat
    80401 taaaggaatt acgaatctaa cccactttga ccaaggaata ttggctactg ctagtgctcc
    80461 cattaaaaca cctgatgtag gtgttatcaa gttagttaca cctataccaa attgataagc
    80521 tgtaactatc atttgtcttg atacatctac taagtcgcca agtggtgcaa gtacaggtat
    80581 tgtaagtgat gcaagccctg atgctgatgg tattaaaaat gctattaatc cttctattaa
    80641 gaaagttaaa tttataaata tagtttttgg taatccattt aataaatttg ctgcagaatt
    80701 taaaattgta tctattataa atccattttc tgctattatt acgattccac gtgcaaatgc
    80761 tatacacaat cctgctgtaa ttaaatctcc tgctccactt ataaatgaat taactatctc
    80821 atcttgttta agccctgatg ctattcctga tattatacct atagctgtaa atatcattgc
    80881 aatttcagtt atgtaccatt ctagtcttaa aactccatat atcataatcg ccatacctat
    80941 tgtgaaaatg gctattacca tggcttctct ttttgtaaat tcctttatat ttgtatcact
    81001 attaaccatt aattcttgat ttagtgatat atcatgtact aaagattttt tagggtcttt
    81061 tttaacttta ttggcataca tcataacaaa tcctatagat atagccatat atattataaa
    81121 cataacaact ctaaactcta ttccagaacc tggtactatt tgtgataatg cttgtgctat
    81181 tcctacagag aaaggattcg tagtagctgc tccaaatcca gctgttgctc ctataaatac
    81241 tgtggccact gctgtcaatg aatcatatcc catactggtc ataagtggaa taaatatcat
    81301 ataaaaaggt agtgtctctt cactcattcc aaacgtcgtc ccacctagtc caaatagaat
    81361 cattgaaatc ggtattatta aaaattgaaa cttcttcatt ttatttacag tatgagctat
    81421 aacagcttct atagctcctg ttttattaac tatcccaaaa gctcctccaa ctattaaaac
    81481 aaatccaact acttcagctg catctataaa cccgtttata ggtgctgtaa atacatcagt
    81541 aattccttgt ggatttgatg gtgctttttc ataagttcca gctacaacaa ctgaccttcc
    81601 gtctatatct actctttcaa aatttccact tggcactatc caagtaagaa ttgccattaa
    81661 cactattagc aaaaatatta ttgtaagtgt ctgtggcata gtaaactttt tcttttttaa
    81721 actgctcatt tttaatctcc ccacttttta aattaaatat tttattattg catcccttta
    81781 tcctattttg tatagatgta aaaaagctca acatggatac atgttgagct aaatgtgcta
    81841 aatacaacat acctgcatct tccctttatc ttgtttaaga tagctctcca tcaaaattcg
    81901 ggataatttt gatgacagta ctgtacctat taaatacagt cccagcacta gcttcggaca
    81961 ctagcacttc ggcacttact ccttttatat tgcctcattg gtttccaacc tcttcaatat
    82021 taatcttagt aaatgcaacc tctacctcaa tctgtttgtt agatgaggta attcttatta
    82081 atttttatta attcaaagta attgtagcat aatatgtcga gattgtaaat attttcagta
    82141 taataattct tactttatga tttcattcca tttttcacaa ataatttttt ctccatataa
    82201 tttaaatact gtagtatatt ttaaatacac acaaactttc cacaaatttt aaattattat
    82261 aataccttta taataaaaaa taaaagctat gtaaacttat caatttacac agctttatat
    82321 acattaatct actccaagta cagctttaag ctttgatgct attgtaataa ctcgtggacc
    82381 aaatataact tgaactgagt ttttcttttt aacaactcca cttgcaccca attcatttac
    82441 ccagaagcca tcttcataga atccatcaat tgaatttagc tctaccctaa gtctagttgc
    82501 acagtttgta acatttttta tattattact tcctcctaaa ccttctatta tagaatgtac
    82561 aagctttgta tctttatcat ctacttcctc ttctactgca ttgttgtatg ctgttttacc
    82621 agcatctaca gattgtcttt ctctatattc tttcttacta taaagcttaa cttcttctga
    82681 acttcttcct ggtgttttta tatcaaactt cttgattgcc catgtaaata ttatataagt
    82741 aactataaaa aatattggta tcaaaaataa taatggtaac gcatccactt tttgtggttg
    82801 taataaatta ggaaacatat ttctaaatga ttctcccatt atagaaacat taaacatttc
    82861 tgtaaataca tacgtcaatc ctgccagtgg tacatatgct acaaaataca ataatggtgc
    82921 aacaaatagg aatgtatact ctattggttc cgttacccct accaacatgg ctgttactat
    82981 tgctggtatc aatatactta ttgctttttt cttattagca ttatcagcca acttatacat
    83041 agctaaagct gctgctggta atattgcaaa atgtattaat aaacgacctg ttgtgaagtt
    83101 acgagttata taagatagtg tatctgggtc tcccatttga gctaatctta tattattaac
    83161 accctcgtaa attgctccac ctacttccat tgttccacct actcttgtat attctatagg
    83221 gaatgcaatt aagtgatgta taccaaatgg taataatgct ttatccattg ctccaaaagt
    83281 aaatgttcct aataatccac tagaacctat ccaattacca agtttagata atgccaaccc
    83341 tactggtggc catataaagt acattgctgt acccaatact attgatgcta taaacatcat
    83401 aatcattgaa aatcttggac ctgagaaaaa agataatgca ctaggaagtt ctatgtcaac
    83461 aaatttgtta tgtactgcac tagctacaaa tccagctatt atagctccaa atatactaca
    83521 atcatatgaa aagattccta agaaagaacc atataaagaa cttcgactat atgcttctgc
    83581 ctctcctaat ccagatgcca taaacgcttc tgctgtaact gtatctgaat ttataccatt
    83641 tgctgctaac aatgtactta taactgtgtg cattcctata aataaaacaa ttcctcctaa
    83701 tgcaccccat cctttttcct ttttagataa tccaaaggct atacctgtaa caaagaatat
    83761 tggtaagtat ctcattacca taaatcctaa atcgtttatt actttaaaga atacatttat
    83821 aaatgaccct tcttttatta gtccgctaag ccctaatgca gaaacgtttt ccatatttgc
    83881 aaaagctgac cctaatccta taaatactcc tgctacaaca agtaatataa caggtatcat
    83941 cattgctcca gaaagtactt gtaatttatc cttcatagta ttatttcctc catttttatt
    84001 gaaatgccag gctatataat gcatatatat atacttctat tgctttgtat aatgtatcta
    84061 tacttatatt ttcatttgcc tgatgtgaat ttggattatc cccctctatt gtgggtccaa
    84121 atgcaactcc attttttaac actcttgcat aagatgcagc tccttttgta aaaagttcgg
    84181 cttcttttcc aaaaccttgt ttatatgcat ttgataattt atttattaat tcactatctg
    84241 gttttacata cagtaatttt aaatccttat atatatcaac tattaaattt tctttttttc
    84301 caatttcatt aattctatta gttataaact cccaacttat acccttagga tatctaaagt
    84361 ctattttcat attcaattca tttttctcta agaagatact cattatacat attgtagaaa
    84421 ctcccatatc tacatcttct ttatacatcc ctaatttttt tccatgatta tcatctgtaa
    84481 agtatgaatt taaaatatcc cttattataa cgcctttatc atttagtttt ttaattttct
    84541 ctaaatcttt tgctaaacta aatgcacagt tatatgacct gtgtggattt ctcgataaag
    84601 ccctttctcc tgtatatctt actaatactt taccttcatc taattcttct atctctgtat
    84661 aataagctaa tgattctact aaatctttct tatcattagt tttaaaaaca gcctcaattt
    84721 tgtcacatac aaatccatct tctttgtttg actttatatc aactaaattg tgatttctaa
    84781 atttatcttt atctattttc tttcttagat tgaagtataa aatacctttt tctccattta
    84841 ctattgggaa gtttccatct ggagaaaatg caaattttgg ctgttcattg acactaaagt
    84901 aatgctccat acattcccaa gtcgtctctt cagctccacc cactatcaat ctaatctttc
    84961 tcttcggctt ttcattaagt tctcttaaga aaagtaatgc atataaaatc cctatcaaag
    85021 gtcctttgtt gtcattaact cctctaccat aaagatagtt atctttttga catactttaa
    85081 aaggtttact cttccaaagt tctttattat atattggcac cacatctata tgattaagca
    85141 cccctactac ttcttctcct tctccatatt ctatatgaat tgcatatcca tcaaagtctt
    85201 ttacaacaaa atctttgtct tttgctattt gaataagctt atcgaaggca tttcttattt
    85261 ctatcccaaa tggttgattt atatctgttg tactttcatc tctaattgaa ggtatttcaa
    85321 ctaaacttct aatatcattt atgatatttt cttgattgga ttttaaataa tcaataatta
    85381 gttctttgtt tactatcatc ttaattattt atcacccctt tatattaatt ttacaaagca
    85441 tttcagttca tatctacatt ataaattttg aatattattt tttcaatatt tcaaatactt
    85501 ctctaagtta ccataatgat acggtaaaca atcaacagat tatgacaaaa tcatactata
    85561 cctattacta atattttaac ttatctatta cgtctttttt aatgtaagtt tattccaaaa
    85621 atacataaaa aaagatgtag ccttagctac atcttcttat atctattcaa cttccattat
    85681 tatgctatta atatctacat ttccaggttc tatcctatct tttactgttc tcttaacaga
    85741 atcagcatca tccattataa ctacaggagt tattatattt aaatcatttg acgttataaa
    85801 atctaaatct acttccatta ttaaatcttt agcttttacc ttatctcctg cctttacctt
    85861 aacatcaaac ggctttcctt ctagtgacat tgtctctaaa cctacatgta ttaatatatt
    85921 tgtattatca ttactcttaa tcattattgc atgctttgta tcaaatacat tgactatttc
    85981 accatcaaca ggagaatata acttaccttc acttggtatt attgctactc catctcccat
    86041 catcttttgg gcaaaaactg catctggaac atcttctaag ttcactaaat ttcccttaaa
    86101 agggctatat attttctcaa tcttattttc ttttttctta aatatattaa acataacaca
    86161 ctctccacat tataaaattt tatgataata tttttcttaa agcttttgct acaccatcat
    86221 ttacattagt atcagttaca aaatctgcca tagattttac ttcatctgta gcatttccca
    86281 tagcaatacc aagacctgca aatttaatca tggatatatc attttcatta tcacctatac
    86341 aaataacttc tttgctatct atacctaata tatcacaaaa ttttttaact gcaatacctt
    86401 ttgaagtacc tttactcata acttcaaagt ttatctttcc agaacttact acttctaaat
    86461 cttcttgttt tttaaattct tcctttgctt ctctcaaaga atctacgttt tctgagaaaa
    86521 gtatacattt taaaatttca ttatcagctt tttctaataa agtttcacaa cttgcatttt
    86581 ctattatttc aattctgtct tcttctttat ttttactatt tattaatcta tatggatgtt
    86641 cttcacctat ttcattgttg gatataacta ttttacagcc tttaaaatgt ttgtttaaat
    86701 tatacttttc acctattgta tagattttct ttagagcttc tttgctcaaa accttcttat
    86761 actcatatcc cagtaattta aaatatgtcc cattagttga tataatatat atatcatccc
    86821 ctaaaacact tgtaaaatat ttcatagcat tataaggtct tcccgtaact aaggctacct
    86881 tgataccctt ttccatggct tcttttagtg ctttaatatt ttcttctgat acttcaaatc
    86941 ctttacccat caaagtacca tccatatcag tacaaattaa tttatatcgc atttgtatca
    87001 catcctagta agatttttct aatatttcaa caaggtcttc tttctttcca aaaggtaaaa
    87061 atcctaaaac tggacagctt gttatttgtt ctaattgttc ctttgttaca ttaaactcag
    87121 acatttttgt cttaagcccc actctcttta aaaaactttc tatttcattt cctaaagttt
    87181 tagctgcttc atcatcttcc actttttcta attcttggtt tagtattctc gctactttgg
    87241 caaatttctc tatattatcc ttatagaact tttctgcaaa ttttgggaac actatagcca
    87301 aagcctcacc atgaggaata tgtgtaactc ctcctattat ttcacttagt ggatgtggtg
    87361 ctgctgctcc agcatttgcc agtgaacttc ctcctaatgt atctgctact gctaactttg
    87421 ttctgtattc tatattattt ttatcttcca ttactttagg tagatagtta atgactaatt
    87481 ccatagattt ttcagacatt atctctgtaa aatcattagc atttggattt atataacttt
    87541 caaatgcatg agtaaaagca tcaaatgctg ttgatgcagt aattctctct ggcagagtta
    87601 acataagctc tgggtcaact atacattctt ttgagaaaca attttgatga aatattgtat
    87661 ttttctcgct tcctctcgat attactgctg cttgtgtaac ttggcttcct gttccagaag
    87721 tagttgatac agctattaat ggtaattctt tttcacttac cttatcgtat attttaaatg
    87781 gatttgtata tgtactaaac atataatccc aatctatttt ttctaaacca aaagtcaatg
    87841 ctaatacttt tgcagtatct atacttgaac ctcctccaac agctaaaaca acgtctacag
    87901 attctttttt agctaattca aacccttcgt ttattaattc tacagttggg tttggctcta
    87961 ctctctgaac ctcccatgac taaagtcaca gggttcctgc ttcacagaat tttgcatact
    88021 aaaatatgtc ttactaattc tccacaggcc atccccgtag ttcctacggt tcttacataa
    88081 gttatttatt ttgaattgtt attagtctta atccttcttt taatatattt atacttgcat
    88141 ttatatctct atcgtgagtt tcattacaac taggacaaat ccattctctt atatttaagt
    88201 ccttcacttc ctcgttttta tacccacatt tattgcatat ttgtgaactt gcaaagaatt
    88261 tacctacctt tacaatttgt ctaccatgcc aattagcctt gtattctaat tgacgaataa
    88321 attctgacca tgatacatct gaaattgagc gagatagttt acgattttta atcatattct
    88381 ttacttgtaa atcttctatg caaataatat cattctcttt tattaattta gtagataatt
    88441 tttgcagaaa atcatttctt tgattagcta tatgttcttg aagtcttgca acttttaatc
    88501 ttgctttatt tctatttaaa ctaccgattg tttttctcga taattctctt tgtaatttag
    88561 caagtttgtt taatgacttc ttaagatact taggattttc tataaattct ccacaacttg
    88621 agatacaaaa ttctttaatt cccaaatcta aacctatatg attattagta ttttcaaatg
    88681 cttcaatatc tacatcagta cagcataatg atacataata tctaccactt ggttctttag
    88741 atatagtagc attaagtatt ctaccttgag gtacttgttt atcccttatc ttaaccatac
    88801 caagtttagg tagttttata tattgaccac aatacataat gtttccattt gtaaagttag
    88861 ttttatatga aaatctatta attttctttg atttaaattt aggaaatcct gctttttctt
    88921 taaagaattt tttatatgca ttatctaaat cttttaaggc gttttgtagt gaaaatttgt
    88981 caggttcttt aagccaattt aattcttttt ttaaattggt taaatcagaa ctacactgtt
    89041 tataagtaaa agtttcttta tcgtttttat aaac
//
LOCUS       DAEHWO010000008        80167 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEHWO010000008 DAEHWO010000000
VERSION     DAEHWO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 80167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80167
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.008"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(121..894)
                     /locus_tag="KNP54_000736"
     CDS             complement(121..894)
                     /locus_tag="KNP54_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBF0891664.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="KNP54_000737"
     CDS             complement(894..1280)
                     /locus_tag="KNP54_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0891665.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="KNP54_000738"
     CDS             complement(1305..1622)
                     /locus_tag="KNP54_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBF0891666.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="KNP54_000739"
     CDS             complement(1634..1894)
                     /locus_tag="KNP54_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBF0891667.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="KNP54_000740"
     CDS             complement(1894..2190)
                     /locus_tag="KNP54_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBF0891668.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KNP54_000741"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KNP54_000741"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBF0891669.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KNP54_000742"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KNP54_000742"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBF0891670.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KNP54_000743"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KNP54_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBF0891671.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="KNP54_000744"
     CDS             complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="KNP54_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBF0891672.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8083..9189)
                     /locus_tag="KNP54_000745"
     CDS             complement(8083..9189)
                     /locus_tag="KNP54_000745"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBF0891673.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="KNP54_000746"
     CDS             complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="KNP54_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBF0891674.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11409..11546
                     /gene="rpmH"
                     /locus_tag="KNP54_000747"
     CDS             11409..11546
                     /gene="rpmH"
                     /locus_tag="KNP54_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBF0891675.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11624..11968
                     /gene="rnpA"
                     /locus_tag="KNP54_000748"
     CDS             11624..11968
                     /gene="rnpA"
                     /locus_tag="KNP54_000748"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBF0891676.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            12000..12251
                     /gene="yidD"
                     /locus_tag="KNP54_000749"
     CDS             12000..12251
                     /gene="yidD"
                     /locus_tag="KNP54_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBF0891677.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            12283..12990
                     /locus_tag="KNP54_000750"
     CDS             12283..12990
                     /locus_tag="KNP54_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBF0891678.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12959..13588
                     /locus_tag="KNP54_000751"
     CDS             12959..13588
                     /locus_tag="KNP54_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBF0891679.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13700..15079
                     /gene="mnmE"
                     /locus_tag="KNP54_000752"
     CDS             13700..15079
                     /gene="mnmE"
                     /locus_tag="KNP54_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBF0891680.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15177..17069
                     /gene="mnmG"
                     /locus_tag="KNP54_000753"
     CDS             15177..17069
                     /gene="mnmG"
                     /locus_tag="KNP54_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBF0891681.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17062..17781
                     /gene="rsmG"
                     /locus_tag="KNP54_000754"
     CDS             17062..17781
                     /gene="rsmG"
                     /locus_tag="KNP54_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBF0891682.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKDEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17944..18729
                     /gene="noc"
                     /locus_tag="KNP54_000755"
     CDS             17944..18729
                     /gene="noc"
                     /locus_tag="KNP54_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBF0891683.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18864..19637
                     /locus_tag="KNP54_000756"
     CDS             18864..19637
                     /locus_tag="KNP54_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBF0891684.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19639..20502
                     /locus_tag="KNP54_000757"
     CDS             19639..20502
                     /locus_tag="KNP54_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBF0891685.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20535..21677
                     /locus_tag="KNP54_000758"
     CDS             20535..21677
                     /locus_tag="KNP54_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBF0891686.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21811..22386)
                     /locus_tag="KNP54_000759"
     CDS             complement(21811..22386)
                     /locus_tag="KNP54_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBF0891687.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22646..23938
                     /locus_tag="KNP54_000760"
     CDS             22646..23938
                     /locus_tag="KNP54_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBF0891688.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24043..24645
                     /gene="yedF"
                     /locus_tag="KNP54_000761"
     CDS             24043..24645
                     /gene="yedF"
                     /locus_tag="KNP54_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBF0891689.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24718..24981
                     /locus_tag="KNP54_000762"
     CDS             24718..24981
                     /locus_tag="KNP54_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBF0891690.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24996..25181
                     /locus_tag="KNP54_000763"
     CDS             24996..25181
                     /locus_tag="KNP54_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBF0891691.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25284..26480
                     /locus_tag="KNP54_000764"
     CDS             25284..26480
                     /locus_tag="KNP54_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBF0891692.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26694..26972
                     /locus_tag="KNP54_000765"
     CDS             26694..26972
                     /locus_tag="KNP54_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBF0891693.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27009..27443
                     /gene="ssb"
                     /locus_tag="KNP54_000766"
     CDS             27009..27443
                     /gene="ssb"
                     /locus_tag="KNP54_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBF0891694.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27462..27689
                     /locus_tag="KNP54_000767"
     CDS             27462..27689
                     /locus_tag="KNP54_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBF0891695.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27832..28152
                     /locus_tag="KNP54_000768"
     CDS             27832..28152
                     /locus_tag="KNP54_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBF0891696.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28160..29116
                     /locus_tag="KNP54_000769"
     CDS             28160..29116
                     /locus_tag="KNP54_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBF0891697.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29127..31121
                     /locus_tag="KNP54_000770"
     CDS             29127..31121
                     /locus_tag="KNP54_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBF0891698.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31122..31571
                     /locus_tag="KNP54_000771"
     CDS             31122..31571
                     /locus_tag="KNP54_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBF0891699.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31590..32918
                     /gene="dnaB"
                     /locus_tag="KNP54_000772"
     CDS             31590..32918
                     /gene="dnaB"
                     /locus_tag="KNP54_000772"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBF0891700.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33123..33431
                     /locus_tag="KNP54_000773"
     CDS             33123..33431
                     /locus_tag="KNP54_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891701.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33513..34802
                     /locus_tag="KNP54_000774"
     CDS             33513..34802
                     /locus_tag="KNP54_000774"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBF0891702.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35128..35203
                     /locus_tag="KNP54_000775"
     tRNA            35128..35203
                     /locus_tag="KNP54_000775"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35161..35163,aa:Lys,seq:ttt)
     gene            35210..35284
                     /locus_tag="KNP54_000776"
     tRNA            35210..35284
                     /locus_tag="KNP54_000776"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35243..35245,aa:Glu,seq:ttc)
     gene            35289..35364
                     /locus_tag="KNP54_000777"
     tRNA            35289..35364
                     /locus_tag="KNP54_000777"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35322..35324,aa:Val,seq:tac)
     gene            35398..35472
                     /locus_tag="KNP54_000778"
     tRNA            35398..35472
                     /locus_tag="KNP54_000778"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35430..35432,aa:Thr,seq:tgt)
     gene            complement(35855..36847)
                     /locus_tag="KNP54_000779"
     CDS             complement(35855..36847)
                     /locus_tag="KNP54_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0891703.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36856..37914)
                     /locus_tag="KNP54_000780"
     CDS             complement(36856..37914)
                     /locus_tag="KNP54_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBF0891704.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38039..39502
                     /locus_tag="KNP54_000781"
     CDS             38039..39502
                     /locus_tag="KNP54_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBF0891705.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39604..40401
                     /locus_tag="KNP54_000782"
     CDS             39604..40401
                     /locus_tag="KNP54_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0891706.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40414..42516
                     /locus_tag="KNP54_000783"
     CDS             40414..42516
                     /locus_tag="KNP54_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBF0891707.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42584..43063
                     /gene="rlmH"
                     /locus_tag="KNP54_000784"
     CDS             42584..43063
                     /gene="rlmH"
                     /locus_tag="KNP54_000784"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBF0891708.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43212..43523
                     /locus_tag="KNP54_000785"
     CDS             43212..43523
                     /locus_tag="KNP54_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891709.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43571..43888
                     /locus_tag="KNP54_000786"
     CDS             43571..43888
                     /locus_tag="KNP54_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBF0891710.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44101..44802
                     /locus_tag="KNP54_000787"
     CDS             44101..44802
                     /locus_tag="KNP54_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0891711.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            45026..46327
                     /locus_tag="KNP54_000788"
     CDS             45026..46327
                     /locus_tag="KNP54_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0891712.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46464..47558
                     /locus_tag="KNP54_000789"
     CDS             46464..47558
                     /locus_tag="KNP54_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBF0891713.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIILLDFIEPWSKFKLILEGE"
     gene            47560..48693
                     /locus_tag="KNP54_000790"
     CDS             47560..48693
                     /locus_tag="KNP54_000790"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBF0891714.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELRRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            48711..49820
                     /locus_tag="KNP54_000791"
     CDS             48711..49820
                     /locus_tag="KNP54_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBF0891715.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            49885..50625
                     /locus_tag="KNP54_000792"
     CDS             49885..50625
                     /locus_tag="KNP54_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBF0891716.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGILSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            50630..51622
                     /locus_tag="KNP54_000793"
     CDS             50630..51622
                     /locus_tag="KNP54_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBF0891717.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYITTGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51810..52691)
                     /locus_tag="KNP54_000794"
     CDS             complement(51810..52691)
                     /locus_tag="KNP54_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0891718.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52964..54352
                     /locus_tag="KNP54_000795"
     CDS             52964..54352
                     /locus_tag="KNP54_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891719.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYANGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54380..55333
                     /locus_tag="KNP54_000796"
     CDS             54380..55333
                     /locus_tag="KNP54_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBF0891720.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            55393..55617
                     /locus_tag="KNP54_000797"
     CDS             55393..55617
                     /locus_tag="KNP54_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891721.1"
                     /translation="MNEKSSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            55610..56122
                     /locus_tag="KNP54_000798"
     CDS             55610..56122
                     /locus_tag="KNP54_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBF0891722.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            56154..57008
                     /locus_tag="KNP54_000799"
     CDS             56154..57008
                     /locus_tag="KNP54_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBF0891723.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57542..58336
                     /locus_tag="KNP54_000800"
     CDS             57542..58336
                     /locus_tag="KNP54_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0891724.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            58440..59246
                     /locus_tag="KNP54_000801"
     CDS             58440..59246
                     /locus_tag="KNP54_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBF0891725.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            59308..59829
                     /locus_tag="KNP54_000802"
     CDS             59308..59829
                     /locus_tag="KNP54_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBF0891726.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            60244..62331
                     /locus_tag="KNP54_000803"
     CDS             60244..62331
                     /locus_tag="KNP54_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0891727.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMDDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            62346..62633
                     /locus_tag="KNP54_000804"
     CDS             62346..62633
                     /locus_tag="KNP54_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891728.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            62660..63931
                     /locus_tag="KNP54_000805"
     CDS             62660..63931
                     /locus_tag="KNP54_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBF0891729.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            63989..64588
                     /locus_tag="KNP54_000806"
     CDS             63989..64588
                     /locus_tag="KNP54_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBF0891730.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQEYLKWHPAGSLGKSIREGI"
     gene            64593..65498
                     /gene="dapA"
                     /locus_tag="KNP54_000807"
     CDS             64593..65498
                     /gene="dapA"
                     /locus_tag="KNP54_000807"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBF0891731.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKSQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            65604..66236
                     /locus_tag="KNP54_000808"
     CDS             65604..66236
                     /locus_tag="KNP54_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBF0891732.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGLNIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNANKIREIIKNVRKI"
     gene            66713..69220
                     /locus_tag="KNP54_000809"
     CDS             66713..69220
                     /locus_tag="KNP54_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBF0891733.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            69562..71724
                     /locus_tag="KNP54_000810"
     CDS             69562..71724
                     /locus_tag="KNP54_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBF0891734.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            71729..72346
                     /locus_tag="KNP54_000811"
     CDS             71729..72346
                     /locus_tag="KNP54_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891735.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLDLSEQADRVIKL"
     gene            72535..72879
                     /locus_tag="KNP54_000812"
     CDS             72535..72879
                     /locus_tag="KNP54_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBF0891736.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            73449..74315
                     /locus_tag="KNP54_000813"
     CDS             73449..74315
                     /locus_tag="KNP54_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBF0891737.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPINK
                     ESGKPCINLQPDFKCSVHNSLIKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESMMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            74428..74832
                     /locus_tag="KNP54_000814"
     CDS             74428..74832
                     /locus_tag="KNP54_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBF0891738.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            74996..75445
                     /locus_tag="KNP54_000815"
     CDS             74996..75445
                     /locus_tag="KNP54_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0891739.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(75601..75978)
                     /locus_tag="KNP54_000816"
     CDS             complement(75601..75978)
                     /locus_tag="KNP54_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBF0891740.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            76240..77157
                     /locus_tag="KNP54_000817"
     CDS             76240..77157
                     /locus_tag="KNP54_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBF0891741.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            77641..79059
                     /locus_tag="KNP54_000818"
     CDS             77641..79059
                     /locus_tag="KNP54_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBF0891742.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            79135..79947
                     /locus_tag="KNP54_000819"
     CDS             79135..79947
                     /locus_tag="KNP54_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0891743.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
BASE COUNT        30661 a         9428 c        13375 g        26703 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ccttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa acacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttgacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctattgcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctagtaagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcat gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tatattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat atctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 tacaatactt ttattttagt tccttctatt tcaactatat ctcctgattt tatctttttt
     7801 cctcttctta attctatttc atcatttact gtcactaaac cttcttgaat taaaaatttt
     7861 gcatgacctc ctgttgatgc aatctctgct aatttaagaa attgatccaa ctttatatat
     7921 tctgattcta tagttatttc agtcataata gttcctcctt gtcactattt taaacaaatt
     7981 cctattgata cactaaaagt atattatacc ataaatatgc ttataaaagg agttgtctaa
     8041 gattagaaaa attttctaca aaagacaact ccttcatgtc tgctatatat ttgatgatat
     8101 tcttactgga agcagtaagt aaatataatt aacatcatct gttggtttaa ttatacaagg
     8161 atttacattt gtagtaaatt ctataaatat ttcctcatta tctatatttt tcaaaccttc
     8221 gataaaatat ctagaattga aagctatatc taggtaatct ccatctaaat ctatttcaac
     8281 ttcttcatac acatttcctt tttctgtatt agaagtaatt gccattactt tatctcttat
     8341 agataacttt ataagattat ttttttctga ttgagacaat aaagacgctc tctctatact
     8401 atttaaaagt tccttagtat ttaatttaac tctgctgtta tgttctcttg gcaataattt
     8461 tttataatca ataaaatctc cttcaagcaa tcttgtaata attttcgtat cattaattat
     8521 aaaaatagca tttttttcat taaatccaac tttaacatta tcctctccag aaagcaaact
     8581 atttacatct ataagtgtct ttccaggaat tatgactttt atattttcag ttaaactatc
     8641 aaccgaacaa ctttttacag ctaatctata tccatcaatt gctactaaat ttaagtttct
     8701 atctacaatt tctaaaagtt ctcccattaa aacaggtttt gtttggtcct gtgagatagc
     8761 aaatacagtt tgtttaatca tattttttag gatttcttga ggtatgctat ataaatcttc
     8821 ttcatttaat tctggtaatt taggaaattc ttttgctgca taacctttaa ttttaaatct
     8881 tgaatttaca caatttatgt aaatattatt ttctgaatca gtttctatct caacaaagga
     8941 atctggtaat tttctaatta tatctccaaa tagccttgca tctacaacaa catcaccttt
     9001 ttctatgatt tctgcttgta cataagtttc tattcctatt tcagcatcat atccagtaag
     9061 ttttaattga ccttcttctg tagatataag tatacctttt aataattcta ttgttgtttt
     9121 tccattaata gctttttgag caattccaat tctatttgct aggatttttt gattacaaat
     9181 tattttcaat gtggataacc tcctctggct ttttatatat aaaaataagt taaaatcata
     9241 gtagtaatag tagtaggtgt tgttgataat gttaataagt atgtataaca ttataaatac
     9301 aaagatatta acatgtgtat aagatgttaa tatctttgtt attttagact tgataatttg
     9361 ttaataattt ttgttcaaaa aaagtattaa caggttattc aagagatata aacatacaat
     9421 tgtgtataaa ttatcccttc aaatctgata taattttgtc tattttagtc ttaatttctt
     9481 cactttcttc tatatcctta gatactttgt catgagcatg aattactgtt gtatggtctc
     9541 tacccccaaa ctcttcacct attttaggaa gggataaatc agtaagctcg cgcgttaaat
     9601 acatagctat ctgtcttgga taagctattg aacgtgttct ttttttagaa ttaaaatctt
     9661 ccatctttaa attgaataca gaagatactt tttcttttat tctgagaaca tttatttctt
     9721 catttttaga agttgttata atatctttta aagcttctgt agcaagatca aaagatatta
     9781 ccctattgct aagagaagaa taagcaacca ctctagttaa tgcaccttct agttccctta
     9841 tgtttgactt aatatttttt gctatatatg acataacctc atttggcaca tctatacgtt
     9901 ctagttgagc cttttttcta agtatagcaa ttcttgtctc aaagtcaggt gcttgaatat
     9961 cagttataag tcccatttca aatctcgatc ttagcctatc ttctagtgta ggtatgtctt
    10021 ttggcggtct atcactagat ataattattt gtttgtttgc ttcatgaaga gtattgaatg
    10081 tatggaaaaa ctcttcttga gttctttctt ttcctgctat aaattgaata tcgtcgatta
    10141 gtaatacatc tacgtttcta tatttattcc taaattcttc gtttttatcg tcttttatag
    10201 agtttataag ttcattagta aatttttctg aagaaacgta aactactttt gagtcttttt
    10261 tttgactaac aatatgatga cctatagcat gcattaggtg agtcttacct aatccaactc
    10321 ctccatacaa aaaaagtggg ttataagctt tagctggaga ttctgcaact gcaacgcatg
    10381 cagcatgtgc aaatctatta ctattaccaa taacgaatgt atcaaatgtg tattttggat
    10441 ttagattggg gtaaagaact ctataattta aatctgtgct atcagaattt aaatcagcaa
    10501 cctctttttc gctcaataca aatttaatat tatatttttt taatgacagt tgactaatag
    10561 catcttcaat taaatgtaaa tatctattct ctaagatatc tttattaaaa tcactaggag
    10621 ccagtaagat taaatcatta agatgtattt ttaatggtac gatgttttta aaaaaggtat
    10681 taaaacttac tgaagttaag tcacctttta ttaattgtag ggttttgtcc cataaagaaa
    10741 ctatatccat aatataaacc tccgaacaga ataattaata ttttccacaa agttattaac
    10801 agaaaagcaa aaatatatat aaattttaca gaataactaa atttatggat aatggtgttg
    10861 ataaattaat aatagtataa attattaaaa aaatatgaaa agatataaac aatatgtaga
    10921 taaagttata aataacataa acatacaata aatggtgatt ataactagag tattgtcagt
    10981 aatcttaaaa gttatacaca aaagtatcca caagctgtga ataatttcta ataagttgat
    11041 aacatttatg cacattatca acaagtatat ttataatatc aaaatatatg tcaaacttca
    11101 atgatttgta actaatttat ccacaatatt aactaattgt tgataaaaat ataaacatgt
    11161 taaaattact ttatttgtgt atataattga aaaaaataat ttagaataaa attaaataga
    11221 tttttactag tattttcaat aaaaaaaata cataatatat atatggtaga ttttgtgata
    11281 taagcgtccc aaaaactcgt tgacaacagt agtaaaagta tttataatta tatgtgttat
    11341 gtttactttg agggtaaagt tattattttt ataaacggaa aataaaatct gaaaggcggt
    11401 gcaaaataat gagtaaaaga acttatcaac caaaaaagag acaaagaagt aaagaacatg
    11461 gtttcagaaa aagaatgaag acgtctaacg gaagaaacgt gttaaagaga agaagagcta
    11521 aaggaagaaa tagattaact cattaattac aaaagggccg ctgcaaaggt ggcctttttg
    11581 tgtaaataat tacaattcat agctgtgttt atggaggtta actatggact ttaataggac
    11641 taaagggttg aaaaaagact ctgattttag aaaagtatat aaacacggca aatcttttgc
    11701 aaacaaatat ttagtaatat atatacttaa aaataaatca gattatagta gagtaggtat
    11761 ttctgtttca aaaaaagtag gaaaagctat tactaggaat agagtaagaa gattaataaa
    11821 agaagcctac agattaaata ttgatgaaaa aattaagcct ggatatgata tagtatttat
    11881 agcaagggta tctagtaagg atgctacttt taaagacata gacaagtcta taaaaaattt
    11941 agttaaaaga acggatattt ctatttaatt gtatgctata aatatggagg ttaatgactt
    12001 tgaataaaat aatttatata ttaaaggaaa taagtaagta tttatcgaat ttatgtattt
    12061 atttagtgag attttatcaa aagtatatat ctcccttaaa gggacctacc tgtagatttt
    12121 atccaacttg ctcacaatat tcaatagagg cgtttaagaa atatggattt gtaaaaggta
    12181 tgtatttaac gataagaaga attttaaaat gtcatccttt tcatccagga ggttacgacc
    12241 ctctaaaata aaagagagta actattagga ggtataaaaa aattgaatat aataggaaat
    12301 ttcttaggat tgattcttaa ggtaatattt gaatttgtta atcattatgg tatttctata
    12361 atacttttta cgatacttgt aaagattatt ttattaccat taacaattaa gcagactaag
    12421 tcaacaaagg caatgcaaga tatacaacct cgtataaaag agatacaaga aaaatataaa
    12481 aataagccag aaaaacaaaa tgaagaaatt gttaagttat atggagaagc taaaattaat
    12541 ccactatctg gttgtttacc tttattaata cagtttccta tattaatagg attatttagc
    12601 gttttgagag aaccagttgc tcatggcgtt tttgcaaaca aagctgcatt tttagcagct
    12661 gacaatgggt ttttatggat aaaaagctta acatcaccag attatgtatt agcagtattt
    12721 tcaggagcaa gtgcatatgt catgcaaaaa gtaatgacac caaaagatca gttacaaggc
    12781 tctatgaaag taatgacata tgtaatggca ggtatgtctt tctattgggg atttatattc
    12841 ccagcaggac ttacattgta ctggacagta agtaacttat tctcaatagc tcaatattac
    12901 ttaataatga atcctttaaa agctaaactg gctgctaact ctaaggagga aaaagttaat
    12961 gagaaaaagc ctaaaattaa taaaaagtaa gagtaaagag gaagctataa gtaaagctat
    13021 agcagagttg aatttaaaag cagaggatat agaagtagaa atacttgaaa atccaagtaa
    13081 agggttttta ggttttatag gtgctaaaga tggtacttat gaaatttttg ttatcgagag
    13141 ggaagtagat gtagctaaaa attttataga ggtaatgttg aaaaatgcaa atgttgatgc
    13201 caaagtcaat gtatctcaaa aagataattt aatcatggtt gatattgaag gcaaagaagc
    13261 tgcaagttta attggtagaa gaggggaaac tttagattct attcaatttt tgactggatt
    13321 agctcttaat aaaataaata aagattctca tacaagagta cttgtagata tagaaaatta
    13381 tagatcaaaa cgagaagaat ctttaataag atatgctaat aaagttgcta gagaagtagc
    13441 gaaaacaaga aaaactaaaa aattagatta tatgaatcca tatgagagaa gaataataca
    13501 ttcagctctt caaaatgaca aatatgtaat tacatatagt gaaggaaccg atccatatag
    13561 aagattagta attgagtgta aaagataaag tcaacctcct aaacattagg gggttttatt
    13621 ttttaatatt attaaatcat taatgattgg ttaaatgtaa atctatatgt aaaaaattat
    13681 gaattaagag gtgataaatt tgtttataga tgatacaatt gcagcaatag ctacagcacc
    13741 tggagaaggt ggtataggta tacttagaat aagtggagaa aaagctttga aggttgcaga
    13801 agaaatcttt aaatctatgt ctggaaagag tattgaagaa tacaataaga gaacattaat
    13861 atatggaaat atagtggata atgaaaatat aattgatgaa gttttattgg catatatgaa
    13921 aggaccaaat tcctatacag gagaagatgt tatagaaatt aattgccatg gtggatttat
    13981 ttcggtaaag aagatattag aattaatact atcaaaagat gttagattag cagaggctgg
    14041 tgagtttact aaaagagcat tcttaaatgg aagaatagat ttatctcaag cagaggctgt
    14101 aattgatgtt ataaaagcca aaactgatat agctcatgaa gttgctcaaa atcaattaga
    14161 aggttcttta tcaaagaaga taagagaatt gagagataaa gtcactgaga tattagctca
    14221 tgtagaagtt gctatagatt atcctgagga agatattgag catataacat atcaaactct
    14281 taaagaaaaa actgatgaac ttaaaaaaga cattaaaaaa ttatatgata cagctgaaag
    14341 tggaaaaata cttagagaag gcttaaagac ggtaattgtt gggaaaccaa atgtaggtaa
    14401 atcttcacta cttaattcta ttttaggaga gaatagagca atagttactg atataccagg
    14461 aactactaga gatgttatag aagagtttgt aaacataaaa ggtatacctt taaaaattgt
    14521 tgacacagca ggtataagag atactgatga tattgttgaa aaaataggtg ttgaaaagtc
    14581 taaagaatca tttactagtg cagatttgat agtaatggtt ttagatgcat ctagaaagtt
    14641 gtcagaagaa gatatagaga tattagaaaa acttaaggat aaacaaacaa tagtgctgtt
    14701 aaataagaat gatttgaaac aagagattga agaagaaaaa atacttaaat atgtagaaaa
    14761 taatagtata ataaaaatat cagctttaca acaagaagga atagaagaat tgcaagataa
    14821 aatagagtct atggtatata aaggtagtat caaaaataat tctagtttag tagtaacaaa
    14881 ttcaagacat aaagatgcac ttagtaaagc atataaatct gcaacagatg ctttaattgc
    14941 tttggaacaa agtatgccat ttgactttgt agaagtcgat ttaaaaaata tatgggacta
    15001 tcttggatat attaatggtg atacagtaac agaggattta ctagataata tattccataa
    15061 tttctgtatt ggtaagtaat gtacaaaagt aaacttgttt ttattataga gatttttaaa
    15121 aaatttgaag tgtttctcat gaaacattaa ttttgaaaag aaaggaatta taaatgataa
    15181 agtttgaagc aggaaaatat gatgttatag tagtcggagc aggacatgct ggatgtgaag
    15241 ctgctttggc tactgcaaga atgggatata aaactttgat aataacaatg tctttggatt
    15301 ccatagcatt aatgccttgt aatccatcaa ttggagggac tggtaaaggt caattagtta
    15361 aagaaataga tgccttaggt ggtcagatgg gattaaatat agacaagaca tatatacaaa
    15421 gtagaatgtt aaatactgcc aaaggtccag cggtacactc tttaagagca caagcagata
    15481 aatttaaata tcatgaagaa atgaaaaaga cattagaaga tgaaccaaat cttgatatag
    15541 ctatggatga agttgtagaa atacttcatg aaggaaatgt tgtaatagga gttggaacta
    15601 aactaggatg ttcatttaaa tctaaagctg taatattggc cactggagtt tatctgaact
    15661 caaagatata tatgggtgaa gttgcatttt atgaaggtcc taatgcattg gggtatgcaa
    15721 aatatcttac agatagctta gttgagcttg gccttagaat gagaagattt aagacgggaa
    15781 ctccagcaag agttcataga gatagtatag acttctctgt aatgtcttta caagagggtg
    15841 atgaaaaagt aactccattc tcatttatga atgaaaatat agaaaaaaaa caagaacctt
    15901 gttatttaac aagaactaca gaagaaactc aaaaagttat actggataat ttaaaaaggt
    15961 ctgctatgta tagtggagta atagaaagta ctggtccaag atactgtcct tctatagaag
    16021 ataaagtagt aagatttagt gataaaacat cacatcaatt atttatagaa ccagaagggt
    16081 taaatactaa agaaatgtat atacaaggaa tttcaactag tttacctttt gaagttcaat
    16141 tagatatgta caaaactata aagggacttg aaaattgtaa gataatgaga cctgcatatg
    16201 ctattgaata tgattgtgtt gacccaactc aactaaaaat aagtttggaa ataaagggtg
    16261 ttgagaactt atttagtgca gggcaattta atggaacttc tggatacgag gaagcagcag
    16321 ctcaagggct tatggctggt ataaatgcag ttagaaagat agaaggaaaa gagccatttg
    16381 tattagaccg ttcagaagct tatataggtg tcttattaga tgaccttgtt actaaaggaa
    16441 ctaacgagcc ttacagaatg atgacatcaa gagcagaata tcgactatat ttaagacaag
    16501 ataatgcaga tatgagatta actcaaaaag gttatgatat aggattagtt aaaaaagata
    16561 gatatgaaag gttcctaaat aaaaaggctg ctgtagagaa agaatttgaa agactaaaaa
    16621 atgaaagagt tacaccaaaa gaagtaaata gtttgttaga agaaaaagga gcaacaccaa
    16681 taaaggttgg aatatctcta tatgaatttt taaagagacc agaggttact tacgaattgc
    16741 ttgaagaatt agggaaaggc gctggagaag atgtttcaag agaagttaaa gaacagtgtg
    16801 taataataac taaatatgaa ggttatatag agaaacaatt gaaacaaata gaccaattta
    16861 aaaaacttga gaataaaaag ctggatgaga aaataaatta ttcatctata gaaggtctta
    16921 gattagaggc tagacagaaa ctagatgata taaaacctat ttcaataggg caagcatctc
    16981 gtatatctgg tgtttctcca gctgatatat cagttttact tatataccta gaacaaatca
    17041 gaagaactag aggtggcaaa ggtgaataat atagaacttc tgaaaaacgg gattgaaggt
    17101 tttaatatag atacgaatga cagtatgtta gaaaaattta aaatctatag agagatatta
    17161 gttgactgga ataaaaagat gaatcttact ggaatagaag atgaaaaaga agtgtatata
    17221 aaacattttt tagactctat ttcagctgta aagaatggat atataaaaaa tgggatgtct
    17281 ataatagatg ttggtacagg tgctggtttt cctggaatac cattgaaaat atgtttagat
    17341 agcttagaac ttactttgtt agattcgtta aataaaagaa taaacttttt agaggaagtt
    17401 agtagagtac tagagttaga taatattaca tttatacatg gaagagctga agattttggt
    17461 aaagatgaag actataggga aaaatatgat gttgctacgg caagagctgt tgctggatta
    17521 ccgattctta tggaattttg tgtaccattt gtaaaagttg gagggtattt tatttgctta
    17581 aaaggtccga atgctaattt agagctagaa gaatcacaaa aggctattga tgttttagga
    17641 ttggagtata ttgaaaaaat agatgtagag ttaccagagg tagatttaaa tcataatata
    17701 ttagttttta aaaaagtgat ggaaacacca gttaagtacc ctagaaaagc tggtaaacca
    17761 gccaaaaatc ctattaagta atgaaaaatt tattattggt aagcttaatt atttctcagg
    17821 aaataattaa gcttactgta aaaaaacaaa aataaaggaa ttattaaagt agatgcagaa
    17881 ataaatttgt atgtacatat agagaacaaa aataatttat atctaaaata agagaggtat
    17941 gttatggaag ataaaagagt tatggagata cctatagaag atgtagttcc aaatccatat
    18001 caaccaagaa aaatattttc acaagtttca ttggaggaat tgagcaattc tataaaggta
    18061 tatggtataa ttcaacctat aacagttaga gcaaaagatg gcaaatatga actaattgca
    18121 ggagaaagaa gattaagagc agctaaatta gcagagctta aaaccatacc agcaattata
    18181 aataatatga acgatgaatc ttctgctgtt ctagcgttat tagaaaattt gcaacgagaa
    18241 gacttaaatt tcattgaaga agcaattggt tatgaaaact taataaaaga acatgctttt
    18301 actcaacagc aattagcaga aaaattgggc aaaaatcaat ctactgtagc aaataagctt
    18361 agaatattaa agcttccaaa cgatataaaa atgaagctaa tagagaataa tttaacagaa
    18421 agacatgcta gagcatttct taaactacca agtgaagatt taatgcaaag tgtgttagac
    18481 aaagtcataa aaaatgaatt gactgttaaa aaaacagaaa aattgataca agatgtatta
    18541 gaagaaacta aagttcaaga agagcctgat aaaaaacaga atataaaggg tgctatgagt
    18601 ataagaattt acataaatac tataaagcag gcctttgatg ctatatcaaa tacaggaatt
    18661 gatgctaagt ataatgaaat agataaggga gattatatgg aagttgttgt aaaaatccct
    18721 aaaaaataga gattactgct taccagtaat ctttttttgt aatataagcc ttgtaatata
    18781 aattgattta tagacattat ttatacttaa aaaacaccta ttcaacattt aaaattaatt
    18841 taattcttaa aggggggaac atcatgggca aagttatagc tgtattcaat caaaagggtg
    18901 gagtcgggaa aactacaaca aatgtaaatt taagtgctag cttaggaact ttgggaaaga
    18961 aaatattagt attagattta gacccacaag gaaatacaac tagtggatat ggtattaata
    19021 aaaacgaagt agaaaataca atctatgaaa ttatgttaga tgggttacat attaaagaag
    19081 caataataag tactgaattt gagaatgtag atgtagttcc atcagctact gaactatcag
    19141 gtgcagagat agagcttaca tctaaaacta atagagagta tattttaaaa aattccataa
    19201 aagcggtaat agatgaatat gattatatat ttttagattg tccaccctca ctggggatgc
    19261 ttacaataaa ttgtttaact gctgtagata gtgttttaat tccaatacaa tgtgaatatt
    19321 atgctttaga aggtgttagt caattaatgg agactataaa attagtaaaa tcaagattaa
    19381 atgctgatat agaaattcaa ggtgttgttt taagtatgtt tgatggaaga gctaatttat
    19441 caatacaagt agttgaagaa gttaagaaat actttaaagg tagtgtatat acaactttaa
    19501 ttccaagaaa tgtaagactt gcagaagctc caagtcatgg aaaacctgta atttattatg
    19561 ataaaagatg tagagggtct gtagcttatt tggagctagc agaagaattt atagatttag
    19621 aagaggagga atggtagtat ggagaataag tctaaaagaa gtaatagatt aggtagaggt
    19681 cttagtgcat tgataccaga aattaaagga gaaacttcag aaaaagaaat agtcaacata
    19741 gatatagaca aaatatatcc aaacgaagtt caacctagaa agcaatttga tgaagaaaag
    19801 ataaaagtat tgtcggattc tataaaaaat tatggtgttt tacagccaat agtggttaaa
    19861 atggatgaaa ataataaata tatgataata gctggagaaa gaagatttag agcatcaaaa
    19921 cttgcaaata aaaatcaaat acctgctata attaaagata tagatatgaa agatataatg
    19981 gagatagcct taattgaaaa cttacagagg gaagatttaa attcaataga agaggctcta
    20041 gcatataaga gtttaataga gcattacaat gtaactcagg aagaaatatc agaagctgtt
    20101 gggaagagta gacctcatat aactaataca ctaagacttt taaatcttgg acaagatgtt
    20161 atagaaatga tagacagtgg tagaatcaca gcaggccatg gtaaggcttt attgagaatt
    20221 gcagataaag atttgcaact tcaaatagcg aaaaaaatag aagaagaaga actttctgta
    20281 agagaagtcg aaaatatagc taaaaaaata tctgaaaata aacaagaaga acctaaaaaa
    20341 tctaaaccta aggatgtatt tattttagat gttgaagata aacttagaaa tatatttgga
    20401 acaaaggtga atatttctaa aggaaagaaa aaaggtaaaa tagagataga atactataat
    20461 gatgatgatt taaatagtat tgtatcaatg cttcttgaat agaacaaaaa tataaaacag
    20521 agaggaagat tgttatgatt tatttagata atgctgcaac tacatatcca aaaccagaaa
    20581 gagtgtataa tgctgtttta gattgtatga aaaattattg tgcaaatcca ggtagagcag
    20641 gccataaact tgctatgaga gctgctaggg agatatatga tacaagagag aatatagcta
    20701 agttgttcaa tgtaagtaat cctatgaata tagtatttac atctaatgca acagattctt
    20761 taaatttagc gataaaaggt gtattacaag aaggagacca tgtaataaca acgtctatgg
    20821 agcataattc agtaataaga cctataaaag cattggaaaa aaggggtatt gaaaatactg
    20881 tagtaaaatg cgattatgag ggatttttag attatgaaga tttagaaaaa tcaataaaga
    20941 gtaatactaa actgattgta acaacacatg cgtctaatgt atgtggaact ttaatagata
    21001 taaaaaaagt tggagaaata gctaaaaaac ataatatact atttttagta gatgcatcac
    21061 aaacagcagg tgtttatgat atagacgtaa atgaatgtaa tatagatatg ttggcaatgc
    21121 caggtcataa atgcttattt ggacctcaag gaacaggtat attatatgta agagaagggt
    21181 tgaacttaaa tatattaaaa gaaggtggaa caggtagtaa atcagaagaa atagttcaac
    21241 cagagttatt cccagataaa tatgaatcag gaactcataa tactccaggt atagcaggtc
    21301 ttaaccaagg tatactattt atatttgaaa gaggaatcaa caatataaga caacatgaag
    21361 aagaattatg tcaatatatg atagacaaat tagaggaagt accagatata aagatatatg
    21421 gaccaaagga cagtaaaaaa agagcatcag taatagctct aaatatagga gatatggatt
    21481 ctggagaggt tactttctta ttagatagtg attataatat agcgactaga tcaggaatac
    21541 attgttcacc actagcacat accactttag gtactttaaa acaaggtgca gtaaggttta
    21601 gtataggata tttcaacaca aaagatgaga tagataaagc agtggaagct ttgaaaaaaa
    21661 tttcaaaaaa taaatagcat gagatttaat aatatagaaa taaaaaaagg ggatatttca
    21721 aaataaaaat ttgaatcatc tccttttttg tacaaaaaag aaaaggggtt cctaagaacc
    21781 tctaatctat ttgataatag tttcaagaaa ttactttaag taatctcctt cttcaagaac
    21841 tatatgacca ctttcgtaat tagaaccatc aacagtaatt tttatttgtt caacattcat
    21901 attttttatg taagtacgag caactgaatc aagcattaaa gtttctgcat cactacctaa
    21961 gtttgacttt gtaaagtcag agctaacatc taatatacca gtttttacac catcaatgtc
    22021 ttttgtagta aatgaattta attttgcaga ttctggaaca actttaagtt tttgaagttc
    22081 ttcaaataaa gtgttctcat caattttatt taaatcaact ttattttcaa ttaaatctgt
    22141 cttatctaca tcaaaagagt aaatagtagc tgattgagtt ttagtttctt cttttggagt
    22201 aggtttagct ttgttattag gaacctcttt ttcagtattg ttttcttctt ttggttgctc
    22261 aacatttgta ttgctcttag tttctttttt agatgaatca cttccatttt gagcattagt
    22321 acaaccaact gcgaatatag atatagataa tatacttaac actaacatta ttttcttatt
    22381 tttcataaaa atttctcctc tcttaaaaac tattcttata tataattata gtcgttatga
    22441 gcaaatatat gaatacaaaa tagtaacaaa tttaaaaaat gatttattta aattaataaa
    22501 actcaaaata aactaaattt tagtcatttt tatgggaaat catttaatgt acagtgaaaa
    22561 tattgtaaaa taaaagtagt gtttttaaaa taaatataag ttataattat attataaaaa
    22621 aatgtcttca aaaggtggga atagtatgga aattttgagc ttaggagaaa agattaaaaa
    22681 attaagaaaa gaaaaaaaca tgacattaaa agaattagct ggagatagga taacagcagc
    22741 acaaataagc catatagaga gggataaatc tcatactagt tatgaactgt tggaatatct
    22801 aggcgataag ctagatgtaa gtgtagaata cttattagag accaaggaaa tgcaatcaaa
    22861 aaagataact gataatttaa tactacagag cgaaatttat ataaaagaaa atgaattaaa
    22921 caaggctgag gaccaaataa aagaagtttt agatatatgt aagagatacg atttaatgga
    22981 gaactatggc agatgtaatt ttttaatggc taatattaat ttgaaaaaat ctaattataa
    23041 tgatgctata gaaaactttg aaaaggcatt gtacttcttt ataaaaaata gtgatagtga
    23101 aaatatactt aagtgttatt taaacatagg gaaaatatat atgcaggaag acttttataa
    23161 aggtgctata agccacttta attttgcaga ggaaattttg tcagagaata aatttgagga
    23221 tgttaacata cacaaggaac tatatagtaa gatggcatat tgttacataa aactagataa
    23281 tccaaatatg tcattgaagt acatagaaaa gataaatgaa atagataata gaaatgatag
    23341 aaaagaagat gtcgatattt tggtgttaaa agcaaataat atgcttgaga ttggaaaata
    23401 tgaagaatca agagattact ttaaaaaagc actaaaaata cttgagagtg aggataataa
    23461 aactggatta gcaaatgtgt atttaacaat ttgtgatgtt tacagaaaaa taggtgaaac
    23521 agatagagta cttgaatatt cacaaaaggt atatgacata aagaaaaatg atgaagatga
    23581 atacatgatg tcaggattat ttaagataat agaagcatat atagataaag aagattatga
    23641 tttagctaga aaatattgta agatagcctt agcttcatca ataaaaaata aaaataaatt
    23701 caatgaatat aaagcattga gattctatgc taatatgtat aaaaatcaga atgaagtaac
    23761 tcttgcaatt gaatatctga ttaaatgcat aaaaatagta tcagatttag gcaacaatag
    23821 aatattggcc aatttatata tagacttagg tcaattatat tcaaatatat caaaagaaaa
    23881 agagttagaa tattatcaaa aaggtgtatt tatgtacaaa aatttagaaa taatgtaggg
    23941 taaataaacc tataagggta tagaaacaat ctataacaag caagataata tctatgataa
    24001 aatataaatt gtatgaatat ttttaaggag atgaatcaga caatgagtat aaaaatagat
    24061 gcgagagggc ttgcttgtcc taaaccagtt ataaatacaa aaagagaatt ggataaccta
    24121 gaagaaggtg ttgtagttac aatagtcgat aatgaaacag ctaaggagaa tatattaaaa
    24181 cttgctaaat ctttaagttg tgaagcaaat attgttgacg aaaaagagaa ttttatatct
    24241 atagaaatta gaaaaggtaa aaatatacta gataaacaaa atgttgtaga taataaagaa
    24301 agtgaattag acaatacatg tatatttata tcttcagata agatgggact tggaaatgac
    24361 gaattaggaa aagtgttaat aaaaggattt atatatacat taacagaatc taaaccttat
    24421 cctaagtatg tacttttagt taatggagga gtaaaattaa gtgctgaaaa tgaagaaacc
    24481 atagaaaatc taaaaatact tgagaatatg ggtgtagaag ttttatcttg tggtacttgt
    24541 ttagattatt ataatttaaa agacaaatta caagtaggta cagttacaaa tatgtatact
    24601 atagttgaga cattaaagaa tgcatcaaat accatttcta tataatgtat gtttgtttaa
    24661 taatataaaa ttaataataa agattaactc aaatagatag tcagaaagga ttaagtaatg
    24721 aatcaaatgt atatagtgtc atttaattcg acacatcatg cgataagatc agaaaagtta
    24781 tttggtgaaa atagtctaaa agtaatggct cttccaacac caagagaaat aacagcaagt
    24841 tgtggaatat caattaaatt ttcttttgaa gatatggaaa agataaaaac tattttagtt
    24901 gaaaataatg tagatataaa aggaatttat tgtataagta aattagaaaa tggctcaaaa
    24961 gaagtagaga agttagatta ggaggctaat tatttatgcc aatggattta aaaataggtg
    25021 atattgttga attaaaaaag caacatgcat gtgggtgtaa agagtttgaa atcataagaa
    25081 cgggaatgga tataaagata aaatgtacta aatgttcaag gctaataatg cttgatagag
    25141 agaccttaga aaagagagta aaaaagctaa taaaaaagtg ataaaaattt aacacttaaa
    25201 aaatgtcaaa taccgtatat taatatccaa aattttggta taataagaat tgaagaaaac
    25261 attttcatgg gggtgcttta attatggcag ttaaatatgc aaaaagaatg caaggattac
    25321 aaggatcaga aatacgtgag cttttaaaac ttactcaaca accacaaata atatcttttg
    25381 ctggtggaat gccggctcca gagttatttc cagttgagga aatgaaaaaa gtatcagttg
    25441 cagtgcttga agaaaatgga agatcagcta tgcaatatac tacaacagaa ggatatgaac
    25501 cattaagaga aaaaatagca gctagaatga atgataaaaa caaaactaat gtaaacaaag
    25561 atgatatatt agttacaagt ggttctcaac aaggtctaga ttttgcagga aaagtattta
    25621 ttgatgaggg tgatgtaatt ttatgtgaaa gtccatctta cataggagct ataaacgcat
    25681 ttaaatctta tcaacctaaa ttcatagatg ttccaacaga ttctgatgga atgataatgg
    25741 aagaattaga aaagatacta gaaacaactg atagaataaa aatgatttat gtaatacctg
    25801 acttccaaaa tccaacagga agaacttggc cacttgaaag acgtaaaaaa ttcatggaaa
    25861 tagtaaataa atttgaaata ccagtaatag aagataatcc atatggagat ttaagatttg
    25921 aaggagagac tttaccatct ttaaaatcaa tggatacaaa aggattagta atattcttag
    25981 gaactttctc taaaatattc tgcccaggat acagattagg atggacttgt gcttctccag
    26041 aaattttatc taagtttaac tttgcaaaac aaggtgcaga cttacaagca tcaactatat
    26101 ctcaaatgga agtaagcaaa tttatggata tgtatgacct agatgcacat gttgacaaaa
    26161 taaaagcagt ttatgttaaa cgtagagatg taatgcttaa gactatggaa gaagagttcc
    26221 cagaaggatt agtatttact catccagaag gtggattatt tacatgggta gagcttccaa
    26281 gtaatttaaa tgctaaagaa ttaatgccaa aatgtttaga taagaatgtt gcttatgttg
    26341 ctggaggagg attcttccct aatggtggta gagaaaatac tttcagactt aactattcaa
    26401 atatgccaga agaaaaaata atagaaggta taaaaaatat agcagctgta ttaaaagaag
    26461 ctatgggtgt agaagcttaa ttaaaaataa taacttatat ataatacaag ggatggttgt
    26521 tgccatccct tgtttgtttg aaaagtatat aattcacctt atactaaact ttgtccaaaa
    26581 tttaaattga cagaaataag aataaatgat aaaatgtgta ggtatgagat tttagtctca
    26641 tttctctgct ctaagagtgt agagccgtta agtccaaagg gaggtgaatt atagtgagaa
    26701 attatgaatt agtttatgtg gtaaagccaa actctgatga agaagtaaga gaggctatac
    26761 taaacaaagt taaggaagtt gttgcaactg acggagaaat agttaaagtt gatacttggg
    26821 gaactaaaaa attagcttat ccaatagcta agtttacaga aggtttctat gtattagtta
    26881 acttcaaatc agcagtagac gttcctaaag agatagacag aaacttaaag ataaatgaaa
    26941 acgtaataag acacatgata gttgttgctt aataactggt tttattataa aaaataggtg
    27001 gtgtttttat gaatcaagtt gtattagtgg gaaggttgac tagagaccct gaattaagat
    27061 acatcccagg tacaggaaca ccagtggcat cctttacaat agccattgat agagactatg
    27121 taaaaaaaga tggatctaaa gaaactgatt ttatacctgt tgaagtaatg ggtaaatctg
    27181 ctgaattttg tgctaactac ataactaaag gtagattagt agcacttcaa ggatctataa
    27241 gagtagacaa ttatcagaca caatcaggtg aaaagagaac ttttacaaaa gtaagtacta
    27301 gatcagtaca agctttggat agtaagaata aatcggaaaa ttcatataga gagagtgctc
    27361 cagcttttga gccaagcttt gaacctcaag gtttagaccc acaaggtttc caagctatag
    27421 atgatgacga tataccattt taaaaaggag ggaaaaaagt catgatgaat aaaaaaagac
    27481 gtaagaaaaa aagagtttgt caattttgtg ctgacaaaaa cgctaaaata gattacaaaa
    27541 gtactcaaag attacaaaag tatataactg aaagaggaaa gatattacca agaagaatat
    27601 ctggaacttg tgctaagcat caaagagaat taacagttgc tataaaaaga gcgagaaata
    27661 tagcactttt accatataca ttagactaaa aaaatgagcc ttgtgctcat tttttattat
    27721 atgtatttat atatctaaat gaggcgagct ataaagctcg tttttttgtt tatatactta
    27781 aatatattat tatttatgat ataatattat atattaagga gggttgtaaa cgtgaaaata
    27841 gataaaggtt ctgagataac gagaaacata aagataatag aatggatgaa aacagaaata
    27901 ttaatgagtg taagtgattt gtttaattta ttgtttaaag gggtaaaacc attagatgaa
    27961 gcaattcaag atactttagc aaatataata atgataacat atctcttagc aaagagatta
    28021 ggaattagtt ttagagatgt ggattataaa gtcaaggaaa aaataaaaat tggtatagat
    28081 gaggaccata gcgttgaaag atggtatgga gatttatcta atttaaaaaa acatatggat
    28141 aatagggagt gatattaaat tgaataataa aattagacta tctaaggcaa tgtctataat
    28201 agttttagct ataataatcg ctttagtaat agcctatatt ccaatgctag gaatatttag
    28261 tatgttagca gctgttccat atgtaattat aggtgctatt actgatagaa agtattctct
    28321 tatatctatt ttggttacat tttgtgtact gattctattt gcagacattt cttatgcatt
    28381 aaatatatgt ataatgtatt ctttaccagg tatagtaata ggaaagatgc taaagagaag
    28441 ctttgaacaa gaggacagta ataaattcga accgatatat ggtggaacca taatatttgt
    28501 actttcaatg cttgtatatt tttttgtatt aaagacattt ttaaatgtga atctattaga
    28561 tgaagtttct aagatgatat cagaaattgt aaatattcaa aaaaatagtt tttctgcaac
    28621 tgaacttaaa gtgtttgata aaatgaagcc agatgagatt gtaagttatt ttacaaatat
    28681 gctaccaatg atgttatttt tacaagggtt gttatcagcg tttgtcacat attatttgag
    28741 tgtatttttt ataaaaagga ttacaaagat gaatataaga tttcctaagt ttgctgattt
    28801 ttatttaccg ggaaatgcta tactcacaac tttcttactt tatttattag tcttatttat
    28861 tcaaattatt ggttcaaaat tatatacaga attaataatg actaatttac agctagtttt
    28921 taatttaatg tttgtaattc aaggtatagc agtttgcatt tatttcttaa agaaatggat
    28981 aagacaggga ccaaataaaa ttatgttttt ttcagggata attttatgtt tatttggatt
    29041 tatgggaata tcttttgttg gtatggtaga tagtataatt gactttagaa aggtaagaag
    29101 ctataaatcc acttaggagg atagaaatga gtaataaaca aacctttaaa ttaaatatgc
    29161 cagaaataaa tttatatata attgttattg gtatttctag tataattttg ctttattaca
    29221 acttgtatgt agggtgttta tttttctgta tttttgtata tatggttttt cacaattgga
    29281 gaactactaa tattagacgt catgaatgga cagagtatat tcaaaattta tctttagata
    29341 tagatgaaac aactaaaaaa gccataataa atcttccaat accattatgt attttagaat
    29401 ttgatggaaa tatatcctgg tataatggaa agttttatga tatgattggt caaaaagatt
    29461 tacttgataa aaatatagag gatatagtta aaaatcttaa tttaagaaaa gtattaaatg
    29521 aaaataaaga gatgtacaca gaaataaact ataaagaaaa agaatataca ataatttata
    29581 atgttataaa aaatgatcaa gaaaaaaatc ctaaatattt gatgatatta tactggatag
    29641 acaagactga atatttaaaa gtaaaacaaa attatgatga tgaaaaaaat gcaatgatgc
    29701 taatacaagt agatggatat gatgaagtat taaaaagtgc agcagaagat aagagagctt
    29761 taattaatgt tgaagtagag aaaatacttt ctgctttaga attaaattca aatggtgcat
    29821 tgagaagaac ttcaaaagac aaattcttct tggtaatgca taaaaaagag ttaaaaaaat
    29881 tggaagctga gaagttttct attttagata caataagaca tattgattat ggaaataatc
    29941 ttcctgttac tataagtata ggaattggta tagatggaga tacattaaat gagaacctaa
    30001 aacttgctac gggtgctctc gatttagcac ttggtagagg tggtgaccag gctgttgtaa
    30061 aaacaaaaga taaatttgtg ttttatggag gaaaatctaa agctgtagaa aagaaaacca
    30121 aagtaaaatc cagattaata ggtcatgctt taagagaggt tatacaacaa agtgaccaag
    30181 tttatataat gggacataaa tatcctgata tggatgctat gggagcagca gttggtgttt
    30241 atgatatatg taaatcctgt aacaaaactg caaacatagt tttacaatct gtaaatgaat
    30301 ctatagaaat atttataaat aaaataaatg aaaataatta ctataaaaag ttgtttattg
    30361 gaaaagagga agctattgac aactgcacta aaaatacatt agttgtagta gttgatactc
    30421 atagaccaaa ttatactgaa tgtgaagaac tgttaaagct atcagagaag gtagtagtta
    30481 tagaccatca tagaagaggt gtagagttta taaatgatgc agtgctttta ttccatgaga
    30541 tatatgtatc ctcaacgtgt gaaatggtta cagagttagt tcagtatatg gatgaagatg
    30601 taacaataaa taaacttaca gctgaagggc ttttagcagg tataagtcta gatactaaaa
    30661 actttgcatt caaaacaggt gttagaactt ttgaagctgc ttcttacctt agaaaagttg
    30721 gagcagatac tatagaggta aagaaattct tcaattctga tgtaaaagat ttcataataa
    30781 aagctgaaat aattcaaagt actaaaataa ttaataatag aatatgttta gcatattcaa
    30841 gtactgagat agatagtata aatgttataa tagctcaaac tgctgatgag ttattaaata
    30901 tcaaagaagt agaagcttcc tttgtattag gtgaaaaaga tgatactata tttataagtg
    30961 cgaggtcttt aggacaaata aatgtacatg tacttatgga aaaattagga ggcgggggac
    31021 acatagatat agctggagca cagttaaaaa atgtttctct aaaagaagct tataagatgg
    31081 taaataaaat aatagaggag tatttggagg aggaagaata gatgaaagtt atattattaa
    31141 aagacgtaaa aggaactggt aaaaagggag aaatgaaaga agtaagtgat ggatatgcaa
    31201 gaaatttctt atttcctaaa aagatggctg tgcaagcaga tagtgtagca ataaaagaat
    31261 taaatgaaaa gaataaatct aaagaaataa aagcacaaaa agagtatgaa gaagcagttt
    31321 tattaggtaa gcaaatggaa gaaattaata tagaaatata ttcaaaagca ggagaaggtg
    31381 gaagattatt tggttcaata acttctaaag aaattgctga gcaattaaag aaacaaaaag
    31441 acatagatgt agataaaaga aaaatattat tagatgaacc aataagatct ttaggttcaa
    31501 ctttcgtaga aataaaaata catcaaaaag taactactaa aataagagtg gatgtaaaag
    31561 aaaaacagta ataactagag gtgattaaga tggaagatat gacgagaatt cctcctcata
    31621 gtgtagaatc agaacaatca atattgggtt ctatacttct agataaagat gctataataa
    31681 cggttacaga aactataaag cctgatgatt tctataaaga ggctcacaaa ataatatatg
    31741 aatgtatgat aactttaagt aataaaggtg agcctataga cttgataaca ttaacagaag
    31801 aactaagaaa acaagggcat cttaatgata ttggaggaat cagttatatt acaagtcttt
    31861 ctactatagt accgacgact tcaaatgtaa aatactatgc tgatatagta aaagaaaagt
    31921 ctgtacttag aaagcttata aaagcttcta atgaaataat aaatctagga tatagtggag
    31981 caactaagat tgaagatgtt ttagaacaag ctgaaaagag tatatttgat atatcacagg
    32041 agaaaactag tgatgatttt aaatctataa acttagtttt gatggatgcc tatgatatga
    32101 tagaaaaatt atacactaac aagagtgatg tcactggtat aactactggt tttaaagatt
    32161 taaacaaaaa aataaatggt cttcaaagga ctgatttaat attaattgca gctagaccag
    32221 caatgggtaa aactgccttt tctttaaact tggttcaaaa tgcagcctta aaaggtgatg
    32281 cctctgtagc tgtatttagt ttagagatgt ctaaggaaca attagtacaa cgtatgttat
    32341 cttcacaatc tagtgtagaa ttaaaaaaaa taaagactgg aacacttaat gataatgatt
    32401 ggcctagaat tatagatgct atggcagtat tatcagatgc caaaatacac atagatgata
    32461 ctcctggtat aaaaatatca gaactaaggt caaagtgtag aaagttaaaa atagaaaaag
    32521 gactagattt agtgcttatt gattatcttc aacttatgga aggtgaaggt aataatgaaa
    32581 gcagacaaca agagatatct aagatatcaa ggtcactaaa aatattagca aaagaattaa
    32641 actgtcctgt agtagcacta tctcagttat cacgtgcacc agaacaaaga gcagaccata
    32701 gacctatgtt atctgattta agagagtctg gagcaataga acaggatgca gatatagtta
    32761 tgttcttata cagggacgaa tattatcatg ctgattctga gagtaaaaat ataggagaag
    32821 taataatagc aaaaaataga cacggtgaaa ctggttctgt ggaacttgtt tggcttggtg
    32881 aagttcaaag atttggggat aagttgagag acctataatc taacgaatat ccacagaacg
    32941 tcctttcttt ctacaggaaa aatgtggata catgtcacta aatatgtcca aacattgaaa
    33001 tttagctaaa aaactatcca cactatccac agatggcctg ttgataagtg tgaataagta
    33061 gataaagcaa gcttttggct tgctttatct gtgtataaat attaattatt aggaggaata
    33121 atatggaaaa aataagctta aaatatatat atcccaatat aattaaagta cttgatgaaa
    33181 taaacttatt tagagtaatt gacaataatt taagagaatc tattgttgtt tatgctaata
    33241 atgtggataa tcagtatcat ataaacatga ctaatacaaa ctttggaaat ataattaaca
    33301 tatgtaaatt agaaaaactt ttagatgtgg ataaatttat ggaaaaagtt ataaaatatg
    33361 aaaaagaaat aatagagaaa gaagagtttt caaaaataga agaatatatg ttaaatattg
    33421 gagaatacta aaaaagttga aaaaaatacg aatgtttgat agaataagta agtaaagtgt
    33481 tcgagagtat ataaaatata gaggtgaatt acatgaaaac agttgcaatt gttggttctc
    33541 aatggggaga tgaaggtaaa ggtaaagtta tagattatct tgctactcaa gcagatgtag
    33601 tagtaagagg gcaaggtgga aataatgcag gacatacatt agttgtagaa ggtaaaaaat
    33661 acgcattaca tctaattcca tctggagttt taaatccaaa tacagtgaat ataatcggaa
    33721 atggaatagt gtttgaccct aaaggatttt tagaagaatt ggaaatgttt aaaacggata
    33781 atataagtac agaaaatata aaaataagtg atagagcaca tgtcatattc ccatatcata
    33841 aagaactaga tgcattgtca gaagaagcca gaggcgattt aaagataggt acaacaaaaa
    33901 aaggtattgg accttgttat atggataaaa cagagagatc tggtattaga atatgtgact
    33961 taatggataa agataaattt gctataaaat taaaagctca aatagatgct aaaaatgaaa
    34021 tagttaaaaa tatatatgga aaagaagaat tatttgattt tgaaactata tataacgaat
    34081 atctaggata tgcagagcaa ataagaaaat atgtggcaga tacgtctgtt attgtatatg
    34141 atgcagtaag agcaggtaaa aaagtattgt ttgaaggagc acaagggact ttattagatt
    34201 tagatttagg aacttatcca tttgttacat cttctcatcc aacatctggt ggatttgcaa
    34261 ttggtgcagg tatagggcca aatatgataa aagacgttgt tggtatagta aaagcatata
    34321 ctacaagagt tggagaagga ccgtttgtta cagagcaaat aaatgaaact ggagataaga
    34381 taagagaaca aggacatgaa tttggggtaa ctactggtag accaagaaga tgtgggtggt
    34441 ttgatgcagt tatagttaag tatgcagcta gagttaatgg attgactagt atttcattta
    34501 tgttacttga tgtattaact ggatttgata agataaaagt ttgtacgtct tataaaatgg
    34561 gcgataagat aataacggat ttcccagctt cattagatga tttagcaaaa tgtgaacctg
    34621 tatatgaaga attagatgga tggaatgaag atataactca aatagataac tttgatgacc
    34681 ttccagaaaa tgcaaagaaa tatgtagcaa aaatagaaga actagttgga gtaagtgtag
    34741 atatggtttc tgttggtcca aatagagctc aaactataat aagaagaaat atatttgctt
    34801 aatattttat caattaaata atttaaaata gttgaagaag agtatctcaa gataatgttt
    34861 atagttatta gagatgctct tttatatttg acttacattg attttttatt aagttaaagc
    34921 tacttataca tattctaact gaaattaaag ttgaatttat gtagatacat ataggttttt
    34981 taaaaagaat tttgttgaaa ataaatggct aaagatgatt ttaattatat tctaaaaaaa
    35041 gtaaaaaaaa ctattgacta aaaattatat agacgctata atataacttg tgagtgaaag
    35101 aaacgacgaa aaaagtcgaa aaaatgtggt ctattagctc agtcggtaga gcacctgact
    35161 tttaatcagg gtgtcccgcg ttcgagtcgc ggatagatca ccaaaatatg gctcgttggt
    35221 caagaggtta agacaccgcc ctttcacggc ggtaacaggg gttcaattcc cctacgagtc
    35281 accagtatgg gactatagct cagctgggag agcacctgcc ttacaagcag ggggtcacag
    35341 gttcgagccc tgttagtccc accaaatttt gaattagaga taaatactag attatatgct
    35401 ggtgtggctc aacggtagag cagctgactt gtaatcagca ggttgtaggt tcgattccta
    35461 tcaccagctc cacaaagtac ataaattcaa attaatataa ttttctatgt tacaggatac
    35521 ttttaagtat ctttttttaa tttcattttt attgtattaa aaatgaaatt aaacatacaa
    35581 caaaattttg aattacttgc aatgtgatag ttttaaatat aaaatttaga atcattctag
    35641 cataatatta tgtaatatag caaatttaat ttatagtatc aataaatata gactactaag
    35701 aatgtaaatg atttgttaga ttaaggtaca ttagatatgt aaatagaaaa ataaaaagta
    35761 tgttttaatt tatgtgatat aagttttaaa cagagaagca agtttgctct tacctctcta
    35821 tttaaaaata aaaaaatgtt ttttaagggc tattttattt aaatctttcc catctcaaat
    35881 catctccagt aaattctaaa atcctaaact tatctaatat tctagagaga gttctttgag
    35941 tgtaagtatt tcctatttga gatggtgtta agttggttga aataatgatt tttttaccag
    36001 caacaagtct tgtatttaca atattgaaga tttctccact agtaaaagaa ttattaagtt
    36061 cagttccaag gtcatctatt attaataaat cacaatcaaa caagttttta taattatctt
    36121 cacttatttg attatttgtg tctcttctaa atttataatc ttcaagaata tctaaaattc
    36181 taaaagaagt ttgatagatt acaacattgc ctttatctaa caattccttt gcaatacaat
    36241 tgcacatata ggtctttcct agtccagtag aaccataaaa cagtagattt tcactattat
    36301 ccttcttaaa atcatgaaca aaattttcgc agatacttaa attatttagc atattttctc
    36361 taggagatat ttcaccatca gagcctttct taggagaaaa tatattcaag ttaaaattcg
    36421 aaaaattttc ctgacttaaa atcctatcta aattagacat tttataagct tcatttacaa
    36481 tttcttgttt gaggcaagaa catttttctc cattaggtaa aaatccttta tctttacaag
    36541 aaatacattg aaactttatt tccaagtaat caagaggtat gttactttca gctaaaagtc
    36601 tttctttctt tacttttaaa gattctatat tctctttagt cttctttaca atttcatctt
    36661 tagacttagg atttaaaagt actatcttag ctaaactgag acctatttta gaaatttcat
    36721 catctataga ttttatctca gggattctat tatatacctc attttttcta tgttctaata
    36781 agagttcatt atcatctctt ctcttagcat atttagcaag tatttttctt attttatcct
    36841 cattcattta atcacctact taaacttttc tttttgactt tttttaataa tctcatcgag
    36901 ctcatcagag gtatactgag tgaatgtttc gttgaaatta tgaaacttag tttttttgta
    36961 agtattgttg ttttgagtag tattaatctg cttcttatta atattctcct taactatacg
    37021 ttcttcctct ttttgcttta aatcatttaa attttttata tttttttcat tccaattttt
    37081 aattatacca tttatataag atatacttgg gtttgaaata ttcttagact tagaacatgc
    37141 atttattatc aaatctatat ccatattaaa tttatcaaac caggtgtcca taagttcttt
    37201 ttctgatttt gatggttgtc ttgaaaatcc caattcattg aaaatcgttt tatataaaat
    37261 atatcgttca cttcttacca aaaagctttc ttcaacatct tttggcgtat ataaatttga
    37321 atcataccaa tttctaataa tgccttcaat gtatttaact ggctttgatg taccagtttt
    37381 atctttgacg tattcatatg cgcaaagtat catatcgggg ctcatattgt atttattcat
    37441 tatatccata atactcatct tttcacttgg gtcgagatat cgcccaacta ttttatttat
    37501 agaattaaac atttttctaa tacttggatt ttcagaagta gatacaactt tatctgtatt
    37561 agattttata gatgaattat tgcttaatat attctcaata tagaaatttt ttaaatctaa
    37621 aaattctatt gaataattaa aattatcata ttcttcattg tcatgtattt ttataatctt
    37681 cttttcttcc cagaatttcc aagcagataa cacatcagac aatggtatat ttaggttttt
    37741 ggctattgaa ttattgtcga acttaggatt agaagtaata tcacatgctt gtctatatcc
    37801 taaaagataa acttttacgt ataacccgtc cgccattggc ataaatatat ctataaagat
    37861 attgggaata gtgatttcac ctaaatctat ttcattgctt tctttaaaaa acattttatc
    37921 acctcagatt aaattatatc attttttata ttatatttgt ctgtaaacaa ataaaaggtc
    37981 acaagattag catgtaaata ttttctaaaa gtattcattt tgaaaaggag gagatatttt
    38041 ggttataaaa ttcaaccaaa aagtaagaag aacattatca gtagcgattc tatttatggt
    38101 attaataata ggttgcttta tagaaaagga tgacagttta gaaacataca aagaaaaaac
    38161 taattcaaaa ataaatcagt ataatatgga tgttatattt gatgatgaga ctaagaggtt
    38221 aatgtgcaat cagaatgttg actacataaa taatacaaaa tcaaacatag ataaaatata
    38281 tttccatata tatccgaatg ctttttccaa gaaagatttt gctccttttg aaaaaagtga
    38341 aatgacaagg gcttatccta atggatttaa cgaaggatat atagatataa agaatatatt
    38401 aaataataat agtaaaatgg agtataaaat taaaggagac aaaaatgaca tattagaaat
    38461 agaattaggg aaagagttaa aaccaaatga aagaatgtca ttagatataa aatataacgt
    38521 aaaaatacca aattcaattg gaagatttgg atatggagaa aatactataa atgttactaa
    38581 ttggtttcct atagcttgtg taaatgatga aaggggatgg aatttaaaga gttatgaaac
    38641 tattggcgac ccattttata gtgagactag cgattttcat gtgaaactat tgattccaaa
    38701 taaatataaa attgctcata caggaaaact tattgatgat aaacatgata ataagaaaat
    38761 gctatatgaa atagaagctg aaaacgttag agattttgca tttatactaa gtagtaaatt
    38821 tgatgtaaac aaagtagatt caaagggagt agctatcaat acatataatt taaataaaaa
    38881 gctttctaaa aaagcaactg aagtggcaaa agattcaata aatatattta gtgaattatt
    38941 tggaaagtat ccttacaaag aattttctgt tgtagcaagt gactttttta taggggggat
    39001 ggaataccct atgcttgtta tgatagacca aagtttatat aatgaaaaaa atgaattttt
    39061 actagaatat gttattgccc atgagacagc acatcaatgg tggtattctg ctgttggaaa
    39121 tgatgaaata agtgaaccct ggttagatga agcacttact gaatattcta caatagttta
    39181 ttttgaacaa aagtatggta aagatatggc aaacaagctt ataaaaacta tggagataca
    39241 gacaaaaagt tatttgagtg aaaatatatt taagccagca aatgagtata aaaattctac
    39301 tgaatacagc ttgaatgttt atacaaaagg cgcaatagca tttaatgaaa taagaaaaga
    39361 agttggagat aaagtattct ttgagacttt aaatgagtac tataataaat ataagcataa
    39421 aaatgctaat ggaagagctt ttgtggaact atggaatagt aaaggtgtag atataaataa
    39481 gattataagt gaatgtaagt aaatagtgaa tgtaagtaaa ttttgtgcag agtattaaat
    39541 tttatttaat actctgtttt tttggtataa tataatttat aaggcagaaa aagaggtgaa
    39601 ggaatgctaa agtattgttc agtagggagt ggtagtagtg gtaattgcca ctatataggg
    39661 tataaaaata ctaatatact agtagatgca ggattaagtg gcaagagaat aactacaggt
    39721 cttaaagaca ttggtgtaga tgcagataaa ttaaaaggaa tatttataac acatgagcat
    39781 gttgaccata taaaaggagc aggtatatta tcaagaaagt ttgatatacc agtatttgct
    39841 aatataaaaa catggtgttc tatgaaggac aaattaggtg acatcaaaga taaaaatatg
    39901 aaagtatttg aaaatgataa aacctactca ttaggtgata tcatagtaag acctttttca
    39961 atagaacatg atgcgtctga cccagttgga tataattttt atacagagag tgatgaaaaa
    40021 atgtctatag ctactgatat aggatgtata actcaaaata taaaaaaaca tctatataaa
    40081 tctaaattag tagtattgga atcaaattat gaccctaata tgcttatgat gggttcatat
    40141 acatatgctt taaagaaaag agtaatgtca agtactggtc atttatccaa tgaagatgca
    40201 gctaatttct gcgttgaact tattaatgaa ggtacagaat ctatattatt agcacattta
    40261 agcaaagaaa ataattttcc tgagttagcg tatgagactt caaaaggagt attagcatca
    40321 aatgatatag tagttggaca agatgtaaaa ctagatgtac tatcacgaaa tgatgtttct
    40381 aatgtttatg agatgaagta gaggtgaata actttgctaa agagaaattt tgaaaatgtt
    40441 gaggataata aaattttata ctctataaag cagggtatga ttttagcgat acctgctatt
    40501 atgactggtt caactgctct tgtaattttg aatcttccaa taaaggctta tcaagaatat
    40561 ttatcaggct tgtttaatgg agaggttaca aatattctta actttataaa tgattctact
    40621 ttaggaatta tttcattaat aatattatta acaataagct atagttatgg aaaaatatat
    40681 gggagcaagt atacagtact tgttcctata gttgcaatgt gctctttttt agtattttca
    40741 catggtaatg agcttaattc ttatatagaa atatttaaaa caaagtggtt atttacatct
    40801 ataattgttt ctatgacatc ttctgtattg tttgtaaaac ttacagaatc ttttgttaca
    40861 agtgtaaagt ttcatacaga aggggctgat gcagacttta atatggtagt ttcggctata
    40921 gttcctttca taatagtagt atttttgttt tctattttta gagtggtaat gataagtcta
    40981 attggcagtt caaactttca agatatattt tataatttat tttcaaatgt ttttaataaa
    41041 atgggaacaa accttatgag tgctctgttg tttatttttt taatgcactt tatgtggttt
    41101 tttgggattc atggtagtaa tgtattagat accgtcgcaa aaaatttatt tgaaaatagt
    41161 atggcaatta acataaattt agttaataat aatcaattac caacagaaat ttttactaag
    41221 accttttttg atacaatggt tttattggga ggatgtggct ctttactatg tttagtaatt
    41281 gcaatttttc ttagtgaaaa acgtataaat gtaagaaagt tagctaaaat tgcttcaata
    41341 ccagctcttt ttaatatcaa tgagatgcta gttttcggga taccaattgt ttttaactat
    41401 attatgtttg taccttttgt aattactcct ataatcttaa ccgttacaag ttatgtggct
    41461 atgtctacag gtattgtacc atgtacagtt tcagctgtag aatggacctc acctatattt
    41521 ttaagtggat atatgtctac aggttcaata agaggtagtt tgttgcaagt atttaattta
    41581 tgtgttggtg ttatgattta tattccgttt ataaaaatgt cgcaaaatag atatacatat
    41641 atgtttaaaa ataatataga aaatttaaca aacttattaa aaaggtatga attaacaggt
    41701 gaacagccta atcttctaaa ccataatggt aaaataggtt caatttcaaa aatgttggca
    41761 tcagacttga agtttgctat gaaaagagga gaaatagagc ttttttatca accacaagtc
    41821 aattataatg gaaatgttgt gggagcagag ggattactta gatggaaaca ttcaatagga
    41881 gggttcattt atccaccact agttataatt ttggctaaag aagaagggtt cttagatgag
    41941 cttggagagt atattattaa taaagcatgt attgatttaa agaagagtga aaagctattg
    42001 agaaatcctg ttaagttctc tgtaaatata tctccagacc aacttgatga ccctaagtta
    42061 ccagagcaaa taaaaaatat cattagtagt aatgatataa atcctaatat gttaggtata
    42121 gaaataacag agcaaattgc attatcaggt tcacaaataa ttattgaacg tatcaatgcg
    42181 atacataact tgggaataaa gttaattatg gatgattttg ggatggggca tagctctctt
    42241 atatatcttc aaaataataa ctttgatata gttaaattgg atggttcatt agttaaagag
    42301 atacttacaa ataaaagaag tagtgaaatt ataatgacta ttgtaaatct ttcaaaaaat
    42361 ttagattttg atatagttgt tgagtatgtt gaaaatatag accaaaggga taagttatat
    42421 ggtttaggat gtgaaatata tcaaggatat tattatagca aagcaatacc ttttgaagag
    42481 tttgtagaat atgcaaatca agaaagagag atataatttt ataagagctt gtaaattcta
    42541 gtaatgcata gatttgtaat aaaattaagt ttaggagaaa tatatgaata taagtatagt
    42601 agtagtaggt aaaattaaag aaaaatattt aaaattaggt attgatgagt ttaagaaaag
    42661 gctttctaag tattgtaagt tagaaattat agagttggat gatgaaaaag ctccagagaa
    42721 tttgagtgtt aaggaaatgg aaattataaa agacaaagaa ggaaagaaaa ttttagggaa
    42781 gataaagcat aatagttatg ttatagcctt ggctattgat ggtaagggtt tatcctctga
    42841 agagcttgct aagactatga gtgatttagc agttagaggt aatagtagtc tctgttttat
    42901 aataggaggt tctttagggc tttctgatga ggttttagga agggctgatt ataggttatc
    42961 cttttctaag atgacttttc ctcatcagat gatgagattg atattgttag aacagattta
    43021 tagggcttat aggataaata atggagaacc gtatcataaa taaatgatac ggtttttgtt
    43081 aatttgacac ttaataatat taaaataaca aaaaagtatt gaaagtatat tgcatttaag
    43141 gtagaattaa ataaaatatt ataacattat aatgtttata tggttgttaa taaaaatttg
    43201 gaggaaaata tatgataaaa ataatgttgg cctgttcagc aggaatgtct acaagtttat
    43261 tagttactaa aatggaaagt gcagctaaag aaaatggtat agagtcgcaa atttgggcaa
    43321 taccagaatc aactatacaa aatgaaatag aaaaatgtga tgtattatta ctaggaccac
    43381 aagttagata tgtattacct aaggctcaag aaattgctaa gccatataat ataccagtag
    43441 aagttataaa tatgatgcac tatggaacag ttaatggaga agctgtttta aatagagcga
    43501 tagaacttaa caacactaag taatataaat tataatgtat ttttaatata taaattggga
    43561 gaatcaaagg atggatgaaa agactataga aatatctttt aatataatag gttatgcagg
    43621 tgaaggtaaa ggattagctt ttgaagcaat aaaagaggct aagaatggaa atatagaaaa
    43681 agcaaaagaa ttattaaaag agtctaggga agttataaat aaagcacata gatatcaaac
    43741 agaattaata caaaacgaag ctagtggaaa caggactgaa ataagtgtca tacttataca
    43801 tgcacaggac cacttaatga atggcatgaa ttttcaacag ttagctgagg aaatcgttga
    43861 tttacatttg aaattacaag ataaataaaa attaaagata ataaattaag agagttctta
    43921 aaagatacat tatgtgtagc acactaattg ttagattatt gattcaatat ttagtgagta
    43981 atacattagg attattttga ggactctttt tatatttagt ttaaagttaa taaatattta
    44041 ttattaataa tataagatta tatgttataa tattataaca tataatttaa gaggtgaatc
    44101 atgttaagaa atcaaccatt atatatacaa gttgtagata tattaaagca aaaaatatta
    44161 aataacgaat ataaaattga tgaaaatatt ccaacagaaa gggagttaga gcaagagttt
    44221 ggagtcagta aaattactat tagaaaagct attgagatat tagaatcaga aggatatgta
    44281 gagaaaaaaa gtggaaaagg gacaaaagta ataagtaata gcctttttaa taagctatca
    44341 aaagcagagt ctttttcaag tatactttta tctaaaggtc ataagttatc taaagagact
    44401 atttcaattg aaaaaataat aaatgataca aattcacaag tatttagtat atttggagaa
    44461 aaatgtagca agattactag aatgtattat ttagatagta agccatatat attttttact
    44521 cattatattc cttttgatga aaatctaact gttgaaagtt ttaataatga aagttcttta
    44581 tatatgtact tatataggag aaatataaat ataactagat ttgaagatga attttttata
    44641 gaagaatcag aactagaggt atcaaaggct ttaaatctag ctaaagacat attattagga
    44701 agaaaaagaa agacctatga tgagaatgat aatatagttg agctatcatt tgcaagatat
    44761 aatacagaag tacaaaacta tgtaattaaa tacgaaatat aataagaatc ctgagtttat
    44821 tgaaatgata atatgctcag gatttttgtt tagttgtaaa aataaaaaat attataacat
    44881 tataatgttt acaaccaaac attataatgt tataatattt ttaataaaca agtgatatta
    44941 tcaattacat aaaaattagt ttatgttatg aaatcgttat tgcattataa ataaaggata
    45001 atatcaataa tacaggggga taactatgga aaaattcgca agttttttag agcgcaagat
    45061 tatgcctgta gcagcgaaga taagtaatca gagacatatg agagctgtaa gagcaggtat
    45121 aatagcaaca ttaccactaa caatagtggg gtcatttttc acaatattat taaacatacc
    45181 tattgatgct tatatggatt ttatagctcc atttaaagca atattagata taccatttag
    45241 atatactgta ggatttttat ctctatatgc tacttttggg atagcatcat cacttgctaa
    45301 aagctacgat ttagatacaa caggtgttgg tatgcttgca gttatggcat ttttagtttc
    45361 tacaatagtt ccaactcaag tagttgaacc agtaggtgga gttatagaag ctggtagatg
    45421 gatggatatg gcaaaactta attcgccatc attatttgga gctatcgtaa catcattaat
    45481 tacagttgaa atatatcgtt ttatgaagga aaagaatatt acaattaaga tgccagcagg
    45541 agttccagta gaggtttcaa attcatttac tgcattatta ccgacagcag taattttaat
    45601 gttattctgg gtaataagac atattctagg atttgatata agtgttgcac taagcgctat
    45661 gttatcacct ttaaaaggat tcttatcagg aaatagttta ggtggtgggt tactgacagt
    45721 attcctaata actttattct gggtacttgg aatacatggt ccagctataa tgggaccagt
    45781 aataagacct atatgggaca tgtctatagc agaaaatata actgcattca cagaaggagt
    45841 atcagctcat gcaatgccaa acatatttac agaacaattt ttacagtggt atgtatggat
    45901 agggggagca ggggctactc ttgcattagt tgtaatgttt atgttttcta agtcacaata
    45961 tctaaaaagt ttaggtagat taggattttt accagggtta ttcaacataa atgaacctat
    46021 aatatttgga gcaccaatag ttatgaatcc aatactaggg ataccattta taattggacc
    46081 tataataatg acaattctat catatgttct tactattaca ggggttatac ctatgatggt
    46141 agcaagatta ccatttgcaa tgccagcacc aatagcagca gtaatgagta ctaactggag
    46201 tatactagca ggtatcttag tattaatcaa ctttgtgata tcatttgctg tttattatcc
    46261 attcttcaaa gtttttgaaa aacaacaatt acaaagagaa caagaagaaa tgagtgaaaa
    46321 tttataaaaa tacatagata tagaggtttt gtactatata aaatatagaa aaagcttata
    46381 agttattaag ggtgaaggta ggaggaatga cctttgcctt taattttata tattttaaat
    46441 aatgtaattt gaggaggaga aagatggaaa gaagattagg aatatcagta tatccagagc
    46501 atagtaacat ggaagatgat aaggcatata taaaaatggc ttcaaaatac ggatttaaaa
    46561 gaatatttat gtgcatgctt tcaattacaa gacctaagga agaagttaaa aaacatttta
    46621 aagagattat aacctatgca agagaattag gatttgaagt aatccttgat atagctccaa
    46681 acatatttga tatattacaa atatcttatg atgatttaac attttttagt gagttaaatg
    46741 ctagtggaat aaggcttgac tatggatatg atggaagtaa agaagctatg atttctttca
    46801 atccatatga tttaaaagtg gaactaaata tgagtaatga tgtagcatac ttggataata
    46861 taattactta caagccaaat gtaaataata tatatggttg tcacaatttt tatcctcaaa
    46921 ggggtacagg cttgccatat gatttttttg taagatgttc aaatagattt aaaaagtatg
    46981 gaataagaac tgctgctttt gttaattcaa aatacgcaac aatagggcct tggaatataa
    47041 atgatgggct gtgtacgctt gaaatgcata gaaacttaga tattgctaca gcaaccaagc
    47101 acttattcgc aacaggattg attgatgatg taattgtagg gaatgcatat gcaagtgaag
    47161 atgaattaaa aagaatgtct gaagtaaata aatatcaagt tgtatttaat gtagtaactg
    47221 aagaaaaaac ttctgaagta gaaaagacaa taatggcaaa tgagcaacac tttagaagag
    47281 gggatataac caaccaagta gcaaggtcta cagaagtaag aaaaaaatat gctaaagaaa
    47341 atttccctaa gcatgataat acgaccatct ttaaaagagg agatgtagtg attggtaatg
    47401 atgactttgg aaagtataaa ggggaattac agttgatact tcaagattgt gcagatgaaa
    47461 gaaaaaataa ggtgggtaga ataaaggaag acgaaataat acttttagac tttattgaac
    47521 cttggagtaa atttaaactt attttagagg gagagtaaag tgaagataga catattaata
    47581 aaatgtggaa aaacagtaga taaaagtata attgatatag ctatattaga cgataaaata
    47641 atagaagtaa aaaatcagat agatgattct aagtatcagg caaatcaaat tataaaccta
    47701 gatggagaaa aatttattag tgctggttgg atagatatac atacgcactg ctacgaaaga
    47761 ctagaccttt ataaggatta tccagatgag gttggaataa aaagcggtgt tactactgta
    47821 gtagatgcag gaacaacagg agctttagat ataggtaaat tttatgaaga tactaaaaaa
    47881 tataaaacaa atgtatatgc tttaataaat attgctaagc agggaataac atctcaagat
    47941 gaactttcaa gtatgatgaa tattgatgaa tatgaactta gaagagcagt taaaaaatac
    48001 aaagattttg ttgttggaat caaagctaga atgagtaaaa gtgttgtaat ttcaaatgat
    48061 gttgaacctt taaaagtagc taaaagaata aaaaatgaac ttaatctacc tatgatggtt
    48121 cactttggga gttctcctcc aacgatagag gatatatttg actatatgga aaaaggagat
    48181 atattaaccc atatatataa tggaaagcca aatggaatac ttagaggcaa tgaggttaaa
    48241 aaagaaatca tagaagctag agaaagaggt ataatccttg atgtaggtca tggaaccgaa
    48301 agttttagta tggatattgc aatgaaatct aaggatgcag gaatttttcc agacactata
    48361 agtacagata tatatattaa aaatagaata aatggtccag tgtataatct atctacaaca
    48421 atggaaaagt ttatatatat gggctattca cttgaagata taatagataa agttactaaa
    48481 aatgcagcag atgcaataag tttaaaaaat aaaggtttaa taaaagaagg atatgatgct
    48541 gatttaacta tatttgatgt ggttaatgaa gaaaaagaac ttcaagattc tttgaataag
    48601 tcagtaatca caagtacgtc tataaagcca agagcagtag tagtcaatgg agaatattta
    48661 aatataggta agtctatagg agagaatgag tagaagggag aaactattgt atgagtagta
    48721 tatttgaaaa atactctgta agacgtgtta taaatgcttc aggcaaaatg actatactag
    48781 gagtatcaac agtagataag gaagttattg aagcaatagg tgaagggtgt aaaaatttct
    48841 ttataataga agaacttata aataaaacag gtgaatatat agcaaattta ttagggtgtg
    48901 aaagtgcact aatagtttct agtgcatctg ctgggattgc acagagtgtg ggagcaatga
    48961 tagcaaaaga tgatatgagt ctagtttaca atgtaaataa tcctaagaaa caagttaaaa
    49021 gggaaataat aattccaaag ggacataatg ttgattatgg agttccagta gaagtaatga
    49081 taagacttgg aggaggagaa gttgttgagg ccggttatgc taatatgtgt aacaaggaac
    49141 atataataag agagataaat gaaaatacag cagcaattat gtatattaaa tctcatcatt
    49201 gtgttcaaaa gagtatgcta agtgtattag atgcagtaca agttgctaaa gaatataatt
    49261 tacctttgat agtagatgca gcagcagaag aagatttaaa tgtatattat gaattgggag
    49321 cagacctagt gatatacagt ggtgctaagg ctatagaggg tcctagctca gggttagtaa
    49381 taggtaagaa aaaatacata gataatgtaa agcttcaatc aaagggtata ggaagagcta
    49441 tgaaaatagg aaaagaaaat attgtaggtc taacatgtgc aattgagaga tatataagta
    49501 atgataaagt aactttaaaa gaaatggagg ataagctaaa tccatttata gacaagataa
    49561 atactataaa gggagtgagt gctagtataa ctagggattc agcaggtaga gaaatacttc
    49621 gtggagaaat tgactttaat gaagatataa taaataagtc aacacaacaa attataaatg
    49681 aacttagaag tggagagata gctatataca ctagagacta taaggctaat gaaggcaaga
    49741 ttgagattga tataagaagt gtaactggaa gtgatttaga tactatttat aataggataa
    49801 aaaatatagt agaaagttag agtgtagagt aagtgacatt ataatgattt aataaattaa
    49861 attttaccaa tggaggggat aaatatgaat tgtataccac aatattataa aaatagagtt
    49921 tgtttaaatg ttcttgcagg aagcataaaa aatgctaaag aagtatatga tgcttgtgac
    49981 gggcatgtat tgataggaat actatcaaag aattatagca ctgtagaagc agctattgaa
    50041 gatatgaaaa aatactcaaa ggaaatagat aatgcaatat ctgtggggct tggagctgga
    50101 gacccaaatc agtcaaatat ggtatctcag atttctaaag aacttcagcc acaacatata
    50161 aatcaagtgt ttacaggtgt ggctacgtct agagcattgc ttggtcaaaa tgatagtata
    50221 ataaatggat tagtttctcc aactggtaaa ccaggatttg taaaaatatc cacaggtcca
    50281 ttaagttcaa aagaaaaaga tggtatagtt cctatagaaa cagcaatagc tatgatgaaa
    50341 gatatgggag gaagctcaat taagtttttt ccaatgggag ggcttaaaac aaaggatgaa
    50401 tatatagaag ttgcaaaagc ttgtgcaaag cataattttt atttagaacc aacagggggt
    50461 atagacttag ataacttcaa agagatagtt caaattgcac ttgatgctgg tgtagaaaaa
    50521 gttatacctc atgtttatac atcaataatt gataaagaaa caggtgaaac gaaagtggaa
    50581 gatataggag tactttataa aataatgaaa gaattattgg gatagattta tgaatatatt
    50641 agcttttggt gaaataatga tgagactttc agtacctgac tacaagttct taacacaaac
    50701 caatgaacta aattatataa ctacaggcac gggattaaat atattatctg gacttaaaaa
    50761 ctttggatac aatacctata tgttgacaaa gttgcctaat aataatgtag gtaaagcatc
    50821 aagtgcaaat ataagaaagc ttggagtaaa agatgacttt atcacgtatg gagggaatca
    50881 tataggagtg tattttcttg aaaatgggta tggagaaaga ccttctgaag tgacttattt
    50941 gaataggtta aatagttcat tttgtgagag taaattacaa gattatgata ttgataaatg
    51001 tttagaagaa atggatatag tccatatttg tggtattgct atgcaactta cagattcagt
    51061 taaagagatt gctttagaac tagctagaaa atcttatgaa aaggggataa aagtattctt
    51121 tgattttaat tttagacaat cattaaatcc agaaaggact tatgatgatt tagtaaatga
    51181 ttataagaaa atactaccat attgtcatgg gctgtttgct agttatagag atataaataa
    51241 gatacttaat atagatagtc taaatataaa atctagttca gaattgatta aaaaagagta
    51301 tgatatagat attgtagctg gaactatgag aagatttgat gatatgaata atagatttat
    51361 aaagggatat atatcaaatg atgatggtta ttttgaaagt agggagtata agctagaaat
    51421 atatgacagg gttggtgccg gagatggata tgtagcagga attatatatt catatttgga
    51481 aaatatgaag agtgaagata tagttgagtt tggggttgct agttcggtgt tagctcatac
    51541 aacttatggg gataattctt tagtaagcac aggtcatgta cttagactga tgaataatga
    51601 aaaaatagat atattgagat aatacatttg tatataataa aatttttatc ttttttagac
    51661 acatttttga cttgcttata tttgttaaac agagttattt ttaatgatta taaatattaa
    51721 attaaaagtt aaataataaa atagtagaaa atagcattaa ctatagaaaa aatggttaat
    51781 gctattttta tcgttaatat tgattaattt tatattatag aaatgaactt ttctaatgct
    51841 ggatttgtat tttttttatt ccatacaact acaacttcaa ttctattttc tacttctttt
    51901 ataggtacta ttgcaatatc acgttctatc attgtatctg taacacaaaa tgaaggtaaa
    51961 atggatattc ccatgttaga agataccaat gattcaatag tattaagatt atttgaacgt
    52021 tgtaccacat taggtacaaa ccctgcttca cgatatctat tctgtatcat tgacttttgt
    52081 ccatactcat cccctgtttc ctttacaaaa ataaatttat catgttgtaa ttcaattaaa
    52141 tcgatagaat cctcattgta aagtggatga ccaggaggta aaagagctac caaagaatat
    52201 ctttctacag ttttatattc aaaatctttt aatggttgat tttctggatt aataacaaaa
    52261 gcgaggtcca tagaattatt ttttactaag tttaaaagtt cggttatttc attagtacaa
    52321 atatccatag atatattagg gtatgtatta gaaaattctt ttaaatattg ttgaagtttg
    52381 tttttttcat atcctattaa ggttccaatg ctcaaagttc caaaaaaacc atgtgcaaat
    52441 tgttgtgttt ttgcaatagc atcattgata ttttttatta tagtacgtgc ctcagataaa
    52501 aaaacttttc cagctggtgt tagttcaaca tgacgtttac ttcttgtaaa tagagttaca
    52561 tttatttgtt cttctaaagc ttttatttgc tgtgtaacag cagtttgaga aatataaaat
    52621 ttttctgctg ttttggtaaa acttagattt tctgctacag atataaaata ttctaattgt
    52681 ttagtattca aataatcacc cctatttaaa cttgattgtt tgtaaacctt atttatctat
    52741 aattaaagct tattatagta taagaaaatt tacttttaaa gaatattaga aaatatttgt
    52801 ataaaaatat atgttttaag tatatcttta cattagattt tataaattta ttaataagaa
    52861 taacttatat attccaatga aaacgatatt ggatttaagt aagtttgtct cataaaatga
    52921 aagtatatca attgataata ctttaaataa gaagggagaa aaaatggaag ataaatttta
    52981 tgcaaaaggc aacggaaata acggatatat taaaaatctt gaagtttgtt cctttaataa
    53041 cttagatgga acttgtggaa tgtttcaaat ggctctgtac aaaagagatg aaaaatacta
    53101 tttatatgga tgctgttttg gaggaaataa aaaaaatgga gtaatgatta gcgatattac
    53161 agacccttat aatccacaat ttataaaaca ttttcaaatg ttagacccta aagagtatcc
    53221 tacaacaaca actcccaaaa ttcaaatagc agatgattta atgatagtag caatgagttg
    53281 tggaagtgga ccaggagcac ttgttgacca agctaaatta gcaaatatta agtgtgaagc
    53341 aggaattaga atatatagtt taaaagaaga ccctttaaat cctaagtttt taggatattg
    53401 ggattgtggc ttaaagcatg taatgggtgt tcatagattc atgtacaatg gtggaagata
    53461 tgtacattta tcaagtgatt gtgttggctt tgaaggtctg atttataggg tcatagatat
    53521 aataaatcct actaatccag tggaaatagg taaatggtgg agaccagacc aatatgcaaa
    53581 tggatatcca aatagaactt ttgatgcagg agcacctcat tgcccagaat ttatggataa
    53641 aggatggctt catggacctc catttgtaag agacggaaaa gcatattgtg gttatggagg
    53701 agctggttta gttgtattag atgttgaaga tttaacaaga ccaagatgct taggtgaatt
    53761 gccatttatg cctgcatttt ctagtagact tgcaggtgca agaactcata cagcattacc
    53821 attgccagga agagatttag tcgttgttca aaatgaggga gaaagattcc agttctttaa
    53881 accagataac attacagatg ttcaagctat gaataatata catatggttg atgttagtga
    53941 cccaacaaaa ccaacattaa ttgctcaatt tccatatcct gaagttccaa aagatttccc
    54001 ttatcctaac tttaatgttg cgggattagg aaaaccaggg ccatttggcc cacataatct
    54061 tcatgaacca atggataata agccatggtt agagcaaaga ggagatagag tatattgctg
    54121 ttatttccat gcagggctaa gggtttatga tgtatcagac ccatattata tcaaagagct
    54181 agcatatttt ataccaccaa atccaaataa aacaccagaa gaatcttatt tcccaggatt
    54241 cccaggacca cgcttggcag taacagaaga tcttatcgtt gatgatagag gctacatcat
    54301 catagatgct ttagatgatg gattctatat attaaaaatg aaagaagatt aaataaatac
    54361 taaagaggga gagttgaaaa tgaaaatact aggtatttct tttggaacaa aaaatggaaa
    54421 taatgacaca atgtgtaaag ttgcacttaa aggtgccaaa gaagcagggg ctgaagtaga
    54481 atttattcaa atgtcatcta ttaacattaa acattgtact ggatgttgtg cgtgtgttaa
    54541 aactttatta tctgggaaag gtagtatgtg tgtattaaaa gatgattttg aatggttgct
    54601 tgacaaaatg aaagatgcag atggtatagt agtttcagac cctatttttg aagaaggggc
    54661 atcaggatta ttccatacta taatggaccg ttttggaccc agagcagata gaggaaataa
    54721 cattatagga acaaaagttg cagaagctat aggaggaaaa attccagatt caagaatgct
    54781 taatgataaa gtaatatcat ttatgggaat aggaggttct gactggggta caagagttca
    54841 atgtgaacat gctatgctag ctctcatacc aatgtggaaa gttatagata atgcttggtt
    54901 cccatgggca aaggaattag taatggatga tacaaggctt gttcaagttc atcaaattgg
    54961 tttaaatata gttgaagcag caaaagattt tgaaaaagct tcatatcaag gagaagaagg
    55021 tgtatgtcca cattgccaca atagattatt ctaccttgag ccaggtacta aaaaggcaat
    55081 ttgtgctcta tgtggtatag ttggagagtt agatactata agtggaaaaa ctatatttag
    55141 ttttccagaa gagcaattag gtcatgctca tgatacttta ccaggtaagt ttatacatgg
    55201 tgatgatatt aagaaaatgg aaggtcatta tgcagaagtt cgtaaaacac aagaatttaa
    55261 agaaagaaaa acatcttata attttataga gccattaact aaagaaaagc aagctggagt
    55321 ttcattagga taataattaa aatactaaga ctctttttta aggtatgtta gatgttatag
    55381 gaggcttatt gtatgaatga aaagtcaagt tttaaacaaa ttgaaattat tttagcagtt
    55441 atttttttgg tacttacata ttacaaggtt agattaactc cagcatttat tgttatattt
    55501 ataccactat atttaagtta ttttgcagta tctatgattg taaatcaaat agcaattaag
    55561 ctattggaga taaggcaagc tagggaagct actaattaca atataggaaa tggatagaaa
    55621 gaaaaaagaa atattaacac tgtctatggg gattgcttta ctacctcctt tatgggcagt
    55681 attagcacct tatataggaa taaaaactgg agctgtagca ctaatctgtg caggattata
    55741 tgtaactaat ggtaataaac aaaaagatgg attaaaaata atgtttggtt tttggtgtgg
    55801 agatttatgg gcagtgttag ccattttaat tatgggatat atgaatttca atcaaaacct
    55861 agaattattt ttaacactta gtatattagg tttttttgca gttgtaattg catccttatt
    55921 tgaaaaaata attttcctac catcatggct ttgtggttgg gctataggtc taactattat
    55981 gacaggtgaa aatattatta atttacaaga tatttgtatt caaattgctg tagctatggc
    56041 agtaggagta tggtacgtgg gtgcaggtgt agatttgttt acaatatata ttttgagtaa
    56101 agataggaaa aagggaaatt gaaagcatgt gaatatactt tgattatagg agaatggcta
    56161 tgggttttga atttaaaata atgagaagtt taatatatgt aggacttgcc aaggaagaat
    56221 atagacctaa gctaatggac tggttatatc gtcaccatat tccagatagt attagcactt
    56281 ttggaccata ttgtactaaa tatgcctttt atcaagcata tcctacacca aatgaaggtg
    56341 agcgttttgg tgcacgtaag atgcaactaa cagaacatta ttggcttgta gatgaacata
    56401 tgcctgagat ggcaaataga attatgacag aatatatgcc tatggatgtt ctacgttggc
    56461 aagggtgtat accagatgta gaaaataaaa gggttcatga aaatgcagaa agtggagatg
    56521 caggacgtgc agtaggtgga gataatggat gtccaccatt tatatttgcc tttgttccaa
    56581 taaactggga agaagacttt agaggaaaag gacgtactgt acaagatgga ccaaactatc
    56641 gttggcaatt tatgattaag tatccagatg gtatctctaa agaagaagga gaaaaatggt
    56701 tctatgatga ggtagtgcca tactttacaa actgttgcta tgttaatcgt tttgtcagta
    56761 gtaaaataat gattaattat ggagcaactg cttttgaccg tgtatcagaa ctatggtttg
    56821 aaggggaaga agaatggtat aaagctgtgg ttgaagagac aaagtcgttt attaaaaaac
    56881 cagaatgggc acaagaagag gagttcccat atttaaaacc acaattcaat atcgcatcag
    56941 tattcttagg tgatatagca actatggatg catactcaca gtatcgtgga tatataccaa
    57001 tgagataaaa attatagttt gtgataagta gaggaggcat ttactcttac tggtagaaga
    57061 agacttattg tatccttaaa agtaggtgaa tatatagttt tatatttaaa tttatataaa
    57121 actaagacta ataaatatga aacaatagaa ttagaataat ttgataatat ttgttaaaag
    57181 agcatttaga atgtgtttaa agattaagat attcctttta tggtagcaga tagttgaaat
    57241 aataaaactg ttatcatgaa aggaatattt ttatgtatag gaaattttta aaaataaaag
    57301 ttaaatatgt ttaagaacat cttaaagtga aagaatcatt gttagaaata tgtagacaat
    57361 atagtcttta taacgtatca tattaacaag tttacacttg gattatgaaa taaaaagagt
    57421 aattccaaag gttgtaaata ctatgctgac tttgatactt caaagtttag gtgattttgt
    57481 aattgttaat agaaatacgt ttaatgagca taaagaattt atctaataat aggagaatat
    57541 aatgtataca attggacaag tatctaaatt tttaggaata tctagagata cactaaaatt
    57601 ttatgaggac aaaggattag taaatcctaa gaaaaatgat gaaaatggat atagaatata
    57661 taatcaggtt gatatctatg atattgcaac aataaacttt tatagagaaa ttgatataga
    57721 aattaaaaag attcaagaaa taagaaaaag taagagtata aacaatttag aactcttact
    57781 agaagagaag gaacaaatca tactaaaaga gatagaatat aaaaagcttc tcttaaaaaa
    57841 ggttcagtta gtcaaagaag attgtgacaa aataaaaaca tattttggaa aatacacaat
    57901 aaaagaaatg aagcctttgg aagtaaaagg taaaataaaa catgttacta actatgagga
    57961 atatgaagcc ttaaaagaga atacaaacaa cttaaaaaaa gcagttacat taactgattt
    58021 aagaagagta ataaatttta atgaagaagg tataatagaa gaaaaattta taattgtaag
    58081 ggaagtagat gactacaaca aaatcataga aggtgaagtt ctatctcatc ccaattgtat
    58141 ttatactatt attgaagatg gcagatggtc aactggagga gaaaatattg ataataaagt
    58201 ggaagacaga ttaagagaaa tagcaataga aaatgaatgt gaattacttg gaatagtcta
    58261 tgttaatata ttgcttacta cttatgaaga agggattgag cgtatatttt tagagattta
    58321 tgcacctata aaataatata aaagcattga cctgggactt actcataggt ttaaactcat
    58381 gatataagca gttataactt atatagcaat taaatattaa tttgaaatga ggattactta
    58441 tgagaacaga gaaatcatta aaaaggccta tagccagttt tattattcta acaaatataa
    58501 tttttttacc acttttttta ttggtagtag tgactataat gttaaaactt ccaacagtga
    58561 tatctgacat tgcgttgtgt atatcagcgt ggtcatccac ttttgcattt atgatattat
    58621 ttaaaaaaat ttatccaggt aagaaatttt tagtacacgt aaaagataga tttagaaata
    58681 aacttaaatt ttcaacagta tctataataa ttagtataca agtcctaata gctgtagtag
    58741 ttatatttat attagcatct aaaaatcatg gaataatgcc taactttaca gtttcatcat
    58801 ggggagcatt tatatattta tttttaaaaa atttatttgc aggatcatta ggtgaggaat
    58861 taggttggag aggatttgtt caaaatcatc ttcagaaaag acattctcct ttaaaagcat
    58921 ccataatagt aggtttttgg tgggggatgt ggcatttacc aatatggttt acaacaggat
    58981 tcaaaggact tgatttaata aaatatatta tattttttat gattgcaatt atatcaatca
    59041 gtattataat gacaactttt tataatctaa ataaaacttt gataatacct attgtaatac
    59101 atcaactatt taatttttta atagggataa ttaatggaga tttaatagag cttataaatt
    59161 actatgcaat gttatattta atatttgcaa ttgcattaat agttataaat ccaggaaatg
    59221 tattatataa aaatattaga gagtaatata tatctttatg gtaagatata aagatattat
    59281 tagaagaaca tccaaggagg aataaacatg gttttactga ttgttgatgc acaaaagtta
    59341 ataacaaacg agaggttata taaatttaat gaatttgtag taaatgtaga aaatttaatt
    59401 gatacagcta gaaaaaataa tatagaagta atatatgtac gtcatgatga tggagttgaa
    59461 aatgaattga ctaaaggtaa aaatggcttt gaaatatacg aaaaatttaa accatgtaat
    59521 ggagaaaaaa tatttgataa aaaagtaaat agtgctttta aagaaactgg tctattagaa
    59581 tacctaacaa ataatggtga aaaagatatt attattgctg gtctccaaac agattattgt
    59641 attgatgcca ctataaaatg tggatttgaa catggattta atataatagt tccagcttat
    59701 tcaaatacaa ctgttgacaa tttttttatg tcagcagaac aatcatataa atactacaat
    59761 gaatttatat ggaatgaaag atatgcgaag tgtatttcat tagaggaaac acttagaaaa
    59821 atgaaataaa aatagagtat gaattgtata tgtacataag ttgatttcat aaaaaaggat
    59881 gttaaattcc aagttaaaaa ttagattaaa tatattatat tatagataag gcacatcaat
    59941 tttattttaa attaatgtgc tttttaattg tagtaattta tttataatca atatgatttt
    60001 tattatttaa atcaattttt cttgagtttc tttgtctaaa gaaacttttt ttatttataa
    60061 aatctacagt tatattatag tatctatttt agagaagttt aatttttgta tcaatctaaa
    60121 acaaaagtta tacttaaatg aaattgaaaa cgataaaatt ctcaaataaa ataagtattg
    60181 tggaggtgat gaaagaatcc aatgataata tgaagactaa tcttaataag aaagtagggg
    60241 ttaatggtag tggacaaaga aattgtatca attctccaga ttttattaaa tagcacattg
    60301 attacaacta atggattaca agaggagtct aattcatcaa agagacaaat tacttataga
    60361 ataaataaaa tcaatgacat gcttaaagta aaaaatgtac cacttatatg tttaagagct
    60421 gataaagata ttatcgttag aaaagaaaca aaaaaagcaa ttaaagaaat tttagaaaaa
    60481 aactattcta agaatactta ttattttagt aagacagaaa gacttttata tatgtattta
    60541 atgcttttta ttaacatgga tgatatttca attaatcatt ttataaattc tataaaagta
    60601 agtaggtcta ctgtaaatct tgatttcaag gatttgatac cagagcttga aaagaagaac
    60661 attaaagtta agaacaatcg tataaatgga tattacatag ttggcaatga gatggaaatt
    60721 aggagagtgc ttattaaaaa tattatagaa actttgtcta atgagaaaag ttcaagagta
    60781 tttgatattt ttattaaaga atataattta gatagttttg aagaggctaa aaaaattata
    60841 ttaaagctaa taaaaaaata tgaaattact tttgttgaag atagattagt agaatttata
    60901 tatatattta tctttctaaa ggcaaggatg tattcaacta gaatagttac tcaggaaaat
    60961 gtagatattc ctaatatttc agttatgagt tcaatgaagg agtataaatt tgctaaggaa
    61021 ttattagaag tatatgggag tgaagataag ataaagcctc acaatataat gtatattagt
    61081 gcttggattt taggtatatc agtaggaaat tatgaagaag atacagaaga taaggatgta
    61141 atttcaaaaa ttgtaaataa aatgatgaca aagtttggat atttaagcgg agtttactat
    61201 ataagccaag aaaaaatatt taaacaatta tattctcatt ttagacctgc ctactataga
    61261 cttttattta aattacctat ttataatccg atttgtgaaa aagtaaaaga agaatataaa
    61321 ttagtttata gaattgtaag taatgcaatg aaagagtttt gcggattatt tggagaagaa
    61381 attcaggaag aagagttagc atatcttaca atgcactttg caacactttt ttcaaataaa
    61441 aaagaatttg atggttttag aaaaagaata gcattaatag tttgttcaaa tggcgttggt
    61501 agttcagcta ttttacatgc agaacttaca aacttatttc ctgacttaca ctttatacca
    61561 atgtcggaat cagttggatt agaaaatata agtgaacctg tagatattgt atttactact
    61621 aattataacg cagagggttt aaaaacagat gtaccagtaa ttaaagtaag ccctgttatg
    61681 accacaaaag aaaaatataa gattacacgt gaagtgtata ttcaattagg tgatattttt
    61741 ttaagacaac ctaaaataga tgaggttatg gatataataa aaaaatatgc aaatgtaacc
    61801 tctgaaagta ttctttcaag tgagctatta gcttatttta cacagataga gaattttaca
    61861 tctaaggaag gagaggggcc tatgctaagt gagattacta atgaaacact agtaaaaata
    61921 aaggtaaaag ctaagaattg ggaggaagct attagacagt cagcttctgt attagttgaa
    61981 aataacaaag taactgaagg gtatgtagat gctatgatta actcagcaaa agcatctgga
    62041 ccatacatag taattacaaa acatgttgca cttccacatg ctagaccaga agctgggtca
    62101 aaagagattg caataggcat tgctacttta gatagtccta ttgagtttgg gaataacgaa
    62161 aacgaccctg taaaatatgt attttgtcta agtgcaatag acaataatag ccatttacgt
    62221 gctatgtctg agctagttga actattggaa gaagatgagt tttttaaggt tttagatagt
    62281 gctaaagaag ctaaagaaat tattgatttt ataaaaacac acgaattata aaggaggatt
    62341 taattatgta taaaatttta atcgcatgta gagcaggagt tggctcaagt ttaatgttaa
    62401 aaataaagac tcaacaaatt attaaggaaa ataactttcc aattgaagta gaacatggtt
    62461 cattggattc actaaatgga ttcaatggag atgctgtaga aacattaatt gatgttgctg
    62521 aagaattaaa aaataaaaat ttgaagtttg atataattgg gattcacaat attgttgacc
    62581 gtaatgaaat aaagacagca ctagaaaaat tccttgcttc aaaagaggga taaatttaag
    62641 atgataagga ggaatattta tggagtttat tattagtttg ctgagtacac ctgctgtttt
    62701 gcttggcgta gttgcatgta taggattgat tcttcaaaag aaatcagctg ttgaagtatt
    62761 tacaggctct tcaaaaacac ttatcggttt tttgatattt ggtattggtg cctctgctat
    62821 gacaggagca cttcaaaatt tcaataaact gttccaacat ggctttggaa ttactggtgt
    62881 tatagcttca ccagaagcag ctacagcact tgcacaaggt acatatggtt ttgcagtttc
    62941 atgtacatta attcttggat tcatattaaa tttagtattt gcacgtatta caaagtttaa
    63001 gaatattttc tttacaacag gtcatagttt gttcttttct tgtgtattag ttttaattat
    63061 gaaagcacat ggatttgata atacaatcac tattttaata ggtggaacta tcttagggtt
    63121 tatgtctgct gcactacctc aattctgtca accatttatg cgtgaattaa caggtggcga
    63181 cgaacaagct attggtcact ttaacatgat tggttatggt ttatcaggtt atattgggcg
    63241 tttattttca aaacataaag atgatacaac agagactata gaatttccta agtggttatc
    63301 aatattcaga gacttcttaa tgggtctatc catagttatg ttaatcttat tttatattgc
    63361 aacattaaaa gctggtcaag catttactca agaaattgct ggttcaacac attggttggt
    63421 ttttccgctt atagaggcat ttacatttgt ggcaggtatg tcaatattga tgtcaggagt
    63481 tcgtatgttc ttagctgaaa taactgcagc atttgtaatc atttcagaaa agtatattcc
    63541 aggttcacgt cctgcgctag atgttccaac cgtatttcca tatgcaccaa atgcagttat
    63601 tattgggttt atatcagcat atgctgctgg tctattagca attgctatta tggcatcatt
    63661 tcctagtata tttcctgtag taattattcc agctgctcac atatgtttct tctcaggagg
    63721 tacagctgca atatttggca atacttcagg aggatggaga ggggctattg ctgggtcatt
    63781 tgttgtgggg ttattacttg catttttacc agttatacta tatccagttt atgggactct
    63841 tggtatagaa ggagcaactt tccctaatat tgattacaac gtagttggtt cgatattaca
    63901 taatatttta caatttataa aacctattta gactaaatta tataaaagta tagtcatagt
    63961 tactatgatt tcaaggagga tacatcttat ggaaaataca ttatctgaat ttttagataa
    64021 tatatctaat gaattgtcag aatttattgc ctcaatagat gagacatcta taaataaagc
    64081 atgcgaatta attcttgaag ctgaaaaaaa tcacggacgt gtacatgtga ctggtattgg
    64141 caaaccagga catgtatcgg gatatatttc atcattgctt tcatctactg gaacgtcagc
    64201 atatatattg catggtacag aagcagtaca tgggtcaagt ggtcaagtag ttgaaggaga
    64261 tgttgttatt gcaatatcaa atagtggtga aactcaagag ttaaaagcaa ctcttaagac
    64321 tctaaaagta aatggagcaa agataattgg tgtaagtggt aatgagagtt catttttaaa
    64381 aaatatttct gatatattcc tgtttgcagg tgttaagcag gaaggagatt gtctcaataa
    64441 agctcctcgt gcttcaattt tagctgaaac aataatatta caatcattaa gtgttgtatt
    64501 acaatatgct aaaggtctta atacacagga gtatttgaag tggcatccag caggaagtct
    64561 tggaaagtct attagagagg gaatataatt ttatgaaata taaagggatt atatgtgcaa
    64621 tgataacacc atttgatgaa aatcaaaata ttaattcaca agcaacatgt caattaattg
    64681 attatttgat tgaaaaggga atttatggat tatttatttt gggcactaat ggtgaatgtc
    64741 atgtattaac agatgatgaa aaagttgaat ttgcaaagat tgttattaat catacaaata
    64801 atcgtgtacc tgtttttgtt ggaacagggg gtaattcaac tcgtgaagtt gtagatttat
    64861 ctaagagaat ggaagcgatt ggagcaagtg cattatctat tattacacca tactttgtta
    64921 caccaacaca acaggaatta atcttacatt acaaaactat tgctaattca gttaatttac
    64981 ctattataat gtataatatg ccaggtaaga ctggaattaa tattgaacca gagtcagtac
    65041 gtgaattatc aaagataaag aatattgttg gaattaagga tagtagtggt aaacttgaca
    65101 acatgaaagc ttatattgaa gcaacgaaga atgagaattt tagtgtgttt tcaggctcag
    65161 attcacttat tctggatagt ctaaaagctg gtagccaagg agctgttgca gcaacaacaa
    65221 acttcctcac agagattggt atctctatct atgaaaactt tatgaaaggg gatttggaag
    65281 aagctcaaaa atctcaaagt agtatagaag aacttcgacg tatactgaaa cttggaacaa
    65341 ttccatctgt tatgaagaaa actattgtct tgaatggaat taatgttgga actgcacgac
    65401 ttcctgtaac tgaaccaact ggggaagtac ttgaagaaat taaacgagta gttgaaaatt
    65461 ataggacaat acttaataaa agtagtgaga atagataata taaataggga aattacactg
    65521 gtatataatt aatatatata ttataaaaca tgactaaaat taatgaataa gtaaagtggt
    65581 ttgatgagta tagaggtgat aatatgaaaa agatgaatat aaccaaaaga atgtcagaat
    65641 gtggggctct tgcaattgta agagaagaaa atcttaaccg tgcatgtgaa attgctgaag
    65701 gatgtataaa aggtggtata acagttatag aaatgagtta taccctaaat aatgctggag
    65761 aaataattca agggcttaat aaaaagtatg gtgaaatact ttgtgtggga gcaggaacag
    65821 ttttggatag tgaaacagct cgtcatgcta tattacatgg agcccaattt attattgcac
    65881 caaattataa tgaaggtgta gcgaagattt gcaatagata tcagattcct tatgctccag
    65941 gatgtacatc attgactgag gcagtagacg cactaagttt aggagcaact tttataaaag
    66001 ctttcccaat atcagatttc tatggaccta aactagtaaa ggtatttaag acaccaatac
    66061 ctgatatgcc agttttagca agtggagggc ttaatattga aaacctacat atatggttag
    66121 aaaatggagt tgatgtatgt ggatttggtg gtttattaac taaaggttct gttgaagata
    66181 ttgctaaaaa tgctaacaag attcgtgaaa tcattaaaaa tgtaagaaaa atttaacata
    66241 gggctgtatc atagtatctt ataattacta tgatacagcc tttttaatat tattcaaatt
    66301 taaaacagtt tacatttcta ttatattaca tataatttca gtaattttat cttaattttt
    66361 ctatctggaa aaaaatgatt taaaacttaa gttatgatat aatttcatta aaagaaggcg
    66421 atttttagta aatatgagaa aataatgtgt ttttagggga aaagttaaat acagatttaa
    66481 gtgaacaaga atcgataatt aagatattaa atggtgaata gggcatcaaa aaaattacta
    66541 aattaaaagt tttagaggga gaatcttagc aagtgtgtgt gaaaattcaa tttcaaacaa
    66601 aaataattgt aaatgaaatc aatttataca cgttgaagat tcacttttat cattatatta
    66661 aaaagcagag tgaattaaaa gtgagtctaa agataggagg ataattaaaa caatgaaaga
    66721 agacattagg ttacatcgaa tgtgtaaaaa agaacaagca acaaagaatg aagttatatc
    66781 agaggatatt ctaaaatcta tgagtattgg ggtcagtaaa cattttttag atgattcatt
    66841 tacaataata tggggaaata catcattcta tcaattatta ggatatacag aagaagaatt
    66901 tttagttaaa ttttctagtt taaaagatta ttatgaacag aatctttatc attttgaatc
    66961 tatgaaaaat cattttttag aggcttatca tcatggcgaa aagagtatag aatatcaaat
    67021 ttgcatttca gcaaataatg gagaccctgt ttgggtaata atgactggta tattaattga
    67081 atcacaagat aatgagaaat caatggtcta tatattgtat tcaaaaatta atgagttaaa
    67141 aataaagcaa gaagaactat ctgatatgga aaaagagagt acagagaatt ttaaatggat
    67201 gatgtcagag tatgctggga atgtttatat tagcgatatg gatacatatg aattactata
    67261 cttaaataag cactcatgca atactttaca ggcatcagca aatgaactta ttggaagaaa
    67321 atgttatgag gtaattcaag gtagaacttc gccatgtccg ttttgtacaa attcgtattt
    67381 aaaaaaagat gacatatatg aatgggaatt ttataataaa aaactgaaac gaacatttat
    67441 aattaaagac cgtatgttga attggcaagg gcgaagagtt cgtattgaat tatcttatga
    67501 tatgtatagt gctgaatata aattagcaaa aaaagatcag gaaagagaat caattttgaa
    67561 aactattcca gcaggaatgg ttagattaga tgcaagagat tatcttacta tactttggtg
    67621 taatgatata tttttgaata tgattgaata tacaaaggaa cagtttgcag aggaacttaa
    67681 taatcaatgt ggatatttat tttctgaaga ttataaacgt agtaagaaac tggcacaaga
    67741 tttgaaggag tctggggata atgttgtatt tgaagcaaaa atatatacac gttcaaggga
    67801 agaacgtata tggactgtta cattgtgtta tatcagtggg gaagacagtt gggatggaat
    67861 accatctttt tatagtatag gtattgacat aacaaaggaa agaaaacaga ttgagaaatt
    67921 acagcatata tcagagaaag atgcattaac aggaatttat aatcgtgctg agactgaaag
    67981 gcagattaag aaatattttg aaaaaaattt aaatgttatg ggtgcactgt ttatgattga
    68041 tacagataat tttaaacaga ttaatgatac agaagggcat atgattggag atatagtact
    68101 tactgagatg gcatcaggta tgaaaaaaat aatgcgtgac agtgatgttg ttggaagaat
    68161 aggtggagat gagtttacaa tttttatgaa gaatatttcc tcagttaaag atgcagaaaa
    68221 gaaagcagaa gaactattgt atatgttccg tcatctattt cagaaagaaa aaagttttct
    68281 aaaagtaact tgtagcatag gaatagctat atatccaaag gatggtacta cattcaagga
    68341 aatatatgca agagctgata aagccctgta tcaagcaaaa aatatgggaa aaaataatta
    68401 tgtaatctac aaccaagatt attttaaaga attagaagaa tttgattgtt cttctcttgg
    68461 tacagttatt gattcagaaa aacaatacgc tgaatatcct gataatctta cacgttatat
    68521 attccgtatg ctttatcaga ctgatgatat agaccaggcg attaatatga tacttgaggt
    68581 tgttgggaaa cagtttgatg taagtcgtgt ttatattttt gaaaatacag aagatggtag
    68641 atatacttct aatacttatg aatggtgtaa tgaaggaatc tcttctcaaa tggcttattt
    68701 gcaaaacagc aattatcaag actatgagga ttatgaaaag ctttttgagg atgaattagt
    68761 tttttattgt cgagatatcc atacattaag tcctaaacta gaagaattgt tttctagtca
    68821 aggtatccac tctacacttc aatgtgcata taaagaagat agagttttca gtggatttgt
    68881 tggatttgat gaatgcacag gactacgtct atggtcacaa gaggaaataa gtacattatc
    68941 attgatttct caaattatat caatgttttt acaacgtaaa aaaaataata aacttaatca
    69001 acagattcaa caataccaga atattttaga taatattgac cagtgtattt gtgtgattaa
    69061 taaagaaaat aattttttat tatatgtaaa taaaaaattt aaaaatacat attctaaatt
    69121 ccaaattgga caaccttatt atcttgattc tatagatatt cataagatat ccattatatg
    69181 gaataaaaaa gaagcatacc tatgtactag cacgatttaa tggtaaagta aagtttatat
    69241 tggacttaaa ttaaatttcg ttttaaataa gatattattt tagttgctta ctgaaaagac
    69301 tagaatctat attaatgaat tatactaatt ttataccact attaaaatat tgtttgctaa
    69361 aaataaaaaa tagccttaaa acagttgatt ataaaaaatt aactgcttta aggctatttt
    69421 tatctttgtg acgaaataga cacttgccat ttagaatgtg acaatatagt agttgtttag
    69481 aaaaggcaca aagcattata ctttaactaa agtaaaatgt attttgcttt tagaataaaa
    69541 acaattagga gggagctata attgaaaaag ataatatatg tattatttac aattgaacta
    69601 ttaatagtat ctttattagg tctaaatata gttaaagata atgaaattaa taatatttta
    69661 tataacgata caacaagtat atctgtaatg tttaaagatt ataaaaagtt aaataaaaat
    69721 tatagtaagt ggattaaaga tattgcagat gaaaataatg tggctatatc aaagtatgtt
    69781 tttaataata atgaaaaatt atctatatat acgactgata caagtttgaa taacaatata
    69841 aagttaaaat caggaaaatt tcctaatact aattcaaatg aatttattag taatataaac
    69901 actaataata gtaatcaagt aggtaaattc tcaactatga gtaaagacat atcaatttta
    69961 attagggatt ttggtaaaat aagtgaagtt ggagaatcag gaatcttata tatttcaact
    70021 caaaatgaag atacaataaa taaaatatta agagaactaa atgtagacag aagtattttt
    70081 gtagcaagat tacatgatag atatgttaac tcaaatttat acttaaatcc ttcaataatt
    70141 agagatttaa tactaattat cctttgtttc ttggctacaa taatacatta ttcaattagt
    70201 gtgagtagag aggcttctat tttaagatta aatggatact ctaagctaga tataattgct
    70261 agagttataa aaaatatact tagaattatg attttatcat ctgtcacagc attattaata
    70321 tatataatct atattttaaa attaaatata ggtgttagag catgcttata ctttgctatg
    70381 ttttcgatta tatgtatttt gataaatatt ttgatatcta tattaatagt tggttttaat
    70441 agtagaagtt ctaaatatgt gctatctcta aatggaaaaa aatcttatgg ttttgtaaat
    70501 ataatgcatt tcacattgaa aattgtattt gtatcatttc ttatattatc cataaataac
    70561 tgtattttaa attataatat gctacaaact cagttaggaa atctatctga gtgggataaa
    70621 gcaaaaaatg tttataatct tactcttaaa gatacaggcg aacaatcttt aggaaaggaa
    70681 gaagtaatta aaaatgccaa gattaaaggt ttctataaaa atttggtaga agaaaaagat
    70741 gctttcttaa tagattcaac taattttgaa aaacttgaag atggaagtta catgtatgaa
    70801 ataaattcaa agggtaaaaa cccagaagta agtcaatatg gtaaaaatat aaaaataaat
    70861 aaaaactatc ttaaagttaa ccctatttac tcaaatggca aagaaatatt taatctaatc
    70921 gattatgacg ataagactat aaatttatta gttcctaaaa agttacaagt acatgaaaat
    70981 gagattaaaa aagagtttag agaattattt tattttgaaa aaatagaagt agaaaatatg
    71041 tacaataaag agttaaatag agagttaaat aaaacaaaga agtccgattt aaatgttaat
    71101 ataatatatg tagataataa tcaaagctat tttacttata actcccttgt tatggatgac
    71161 aataggaatc tcattgatga cccaatagca atagttgaca tagataatat tgatgattct
    71221 ttttatcttt cttatatatc tagatgtgta tattttaatt ctaagaaatt agatgccctt
    71281 gcagatataa gtagcattat tgaagctcaa ggtgtagaag cgcatatcca aagtttacat
    71341 gctgtttata atgagtatgg tttagaaata aataaactag aaaaatattt gaatagtgaa
    71401 atttttacta taataataat agcaatatca aacttaatga ttacctacaa tatagtagct
    71461 agctactatg aaagaaataa atataagtta tatattaaaa aaatatttgg ttactcaact
    71521 acagctagaa gtatgttgtt aatagtctca ttaatattaa caaacattat tccaataggc
    71581 attatatcaa caagagtaga tttaagtaat aatattatct tatttggact tctaatatta
    71641 gttatagaag taattgtatc tattgtatta gacaagatta tctcaaatag ttcatttaat
    71701 aaaattataa aaggagaaca ttaaaaagat gatttcatta ataaatatat ctaaaaaatt
    71761 taaagataaa tctataatag acaaatttaa cctagaaatt tctaagggcg agtttgtagc
    71821 gataacagga aatagtggtt caggtaagac aactttactt aatataatgg gattattaga
    71881 aaaacctaat tctggtgata ttataataaa taatataaaa aatccaaata gtaaacagat
    71941 aagaatttta caaagggatt tttatggcta tctatttcaa aattatgctt taattgagaa
    72001 tgaaaatgtt gaaaataact tgaaaattgc tttaaagtat caaaaaaata tcaatcataa
    72061 tgaaaaaata aattacgcac ttgagtctgt aggtcttaga aaatacaata aaaaaaagat
    72121 atacgaattg agtggaggag aacaacaaag ggtagcatta gcaagagtaa tattaaaaga
    72181 atgtgaagta atatttgcag atgaacctac aggtaattta gataaaaaaa atagagacat
    72241 agtatttgat atacttaaaa gtctaaataa gaatggtaaa actatcgtat ttgtaactca
    72301 tgatttagat ttatcggagc aggcagatag agttataaaa ttgtaataat ataaactata
    72361 ataaatataa gaaagagatt acagctaaat taagtttaat aataatacga atagaattta
    72421 aacattaagt aaattagtag tttgtaaata taagtataat atgatatcat aaaggctcaa
    72481 aagaaatttt atataataag aaatctaaaa ataacaaatg gaggacatat aaagatggaa
    72541 aatttaccaa attgcccgaa atgtaattca gaatatactt atgaagatgg aactctttta
    72601 gtttgtccag aatgctctca tgagtgggca ttaggattgg gagctgaaga agattcaaat
    72661 attatcaaag atgtaaatgg aaatgtatta aatgatggag attctgttac agtaattaga
    72721 gaccttaaag taaaaggaag ttcatcatct ataaagattg gaacaaaagt gaaaaatatc
    72781 cgtttaatcc atgactcatc agatggacat gatatagaat gtaagataga tggttttgga
    72841 gctatgaagc taaagtcttc tgttgttaaa aaagcgtaat attataaata agctgtagtg
    72901 tttattgttt ttcagtacag tataaaacca taagaatcta ttaagtaata aaagtttgtt
    72961 tatttatctt tatattttct tatggtttta ttaaatataa attttattga acaccaaaat
    73021 attctctcct ctacaaataa gccaatctta tttaaactaa tatactttgt actatttata
    73081 ctgaaattgt aaatttaaat gctatgttat ttaggtttgt atagttaatt tatatatttc
    73141 tgattttata aattgtattt attattatat cttgattcta aaatcattaa aaatttcaac
    73201 ttctataaag atttacaatt tatcaaatac attatgagta tataaacaat ttattattac
    73261 agtgctacat ttaaaataag tcttagtata aaggtattgt tacaagtata aagaaactta
    73321 tgtatgctat tggaataaat aataccttaa attataatta agaataagaa ctgttaaata
    73381 agggacttga ttatcattta gttatagata atataatatt aaaaataaag tttaagagga
    73441 gaaaaaatat gatagatata cataaaaata tatatgataa taagttattt gaggagctaa
    73501 agattgactg taagaagtgc tttggacttt gctgtgtagc tctttatttt tctgcttcag
    73561 atggatttcc tatcaataag gaatcaggaa aaccctgtat taatttacaa ccagatttta
    73621 aatgttctgt acataatagt cttattaagc gaggttttaa agggtgtact gcatatgatt
    73681 gttttggttc aggtcaaaaa gtagcacaag taacatataa ggggatagac tggatgcaat
    73741 caccagaact aacaaatcaa atgtctgaag tgtttttaat tatgagacaa ttacatgaaa
    73801 tgttatggta tcttaaagaa gcatctgtat taaatatatc agatacaatc aaatcaaaaa
    73861 ttgatttaat aattgaagaa actgaaaaga taactaatat gggtccagaa cagataatta
    73921 atttggatat catatcacat agaacaaagg ttaatttatt attatcacaa gcgagtgagt
    73981 ctatgatggg aaaggttaaa tcatttatca agacttctac tcttaaaaac atgaaaaaat
    74041 taagtaaaaa tatagattta ataggagcag accttagaaa aataaatcta ataggagcag
    74101 atttaagagg tagatttcta atagcagcaa atttaagaaa tacagatttg agtggggcaa
    74161 atttaatagg agcagactta agagattgtg atattagagg tgctaatctt gaaaatagta
    74221 tatttttaac acaattacaa gtaaatactg caaaaggaga ttctagtacg aagttaccag
    74281 cttcactaat acgccctaaa tactgggaaa aataattaaa ttaatacata attttacaaa
    74341 atatgaactt ttttgacttt aattcatatt atacattaga gattctttac aagaatttct
    74401 taatataata tagggagaga tataaaaatg agttatcaaa attataaatg tgaaagagat
    74461 tatgtgtatg atgattataa atacaataag tgcaacaagt gctataatga ttatgaggaa
    74521 atgacacatg ttcatgaata ttcagaaagt gttaagttag cagaagaatg tgaggataga
    74581 cataaccacc gtgcagcagg ggttactggt gaagttatac caataaatgg aggtacaaat
    74641 catgttcata aaataaatga taatgtagat ttccttgacc atttccataa gatatgtgtt
    74701 acaacagggc cagcaattag aatacctgga actgataaac acattcactt aatatgtgga
    74761 gaaactactg ttaatgatgg tcattgtcat aaattccttt ttactactca aatagaagca
    74821 cctttagtat aagctgatgt gaattattgt agtgaatttg ctagattata gtataatata
    74881 taatagataa tatttaaact taatgaggac tatgatattt aaccttcgta gtcctttcta
    74941 agttttgtat aaaaaagtgt tatgcaatta aaagtgatat agggaggaaa tttttatgaa
    75001 atctggaata attcttgaaa tgaaacaaat aaattcaaca gaatatgacg aaatgttgca
    75061 agtctgggaa tcatcagtaa gagcaacgca tgatttttta acagaaaaag atattgaatc
    75121 tttgatacca ttagttgaga ttggacttaa agaagtagaa aatatagttt gtataaaaga
    75181 taatgatata ataaagggct ttataggaat agataaagat aaaattgaga tgctctttat
    75241 agaagataaa tatagaggaa atggtattgg taaaaaatta ataaaatatg ctatagataa
    75301 atacaatgta aaatatgttg atgtaaatga gcagaataaa aaagctgtag gattttatat
    75361 tcacttagga tttaaagtgt ttgataggtc tgaaatagat ggacaaggga acccatttcc
    75421 aatactacat atgaaattaa tttaaagtta tacttcccac ttattcgcaa aaatatttac
    75481 ttaaattttt atacaaataa aagtcgtgac agtcttagga cacgactttt ttactacact
    75541 attaaattga aatttatctg ttctatatta tgattattag atgtagtttt tttattttaa
    75601 ctatgtactt aaataccaag tatacccata cctatcaagt acttcagcag cgccatcatt
    75661 ttgatgtggt ggtgggtgtg gtaaaaattc ttgtacaagt gtaccacctt cggcaagttt
    75721 tacagatatt tcttctatcg cttctcgaga tggtagaaca acacaaatcg ccatgccaga
    75781 aattacaaca ggcttgtctg tatccgcacc cattatacaa ccttcgtatt ttgtgaaagt
    75841 aacacttgcg tgcataatag gattgtttgg attgctgtct aatcgcgcaa atatagtttt
    75901 tcctcctccg aaagcctcag cataaaaatt aaatgctttt tcacaagtac cattaaatat
    75961 taaatatgga gttagcatga ccaatatatc ctccttgata tagaataatt tatagttgca
    76021 cctgataatc taaattatga tttagtaaat tgtatcatag ggaaaccttg aagtatataa
    76081 ttttttatta ttatattata caaatttatt aatttaaaaa aatgttatat gtacggaagg
    76141 tttacaggat aaaatataat aaaaagatta aggtgacatt ataaaaaatg tatattgaca
    76201 ttgacgctac gtaattgtat atactttgtc ttaaaggaga tggtaaatat gaatattata
    76261 gaaattcgct cagataaaat atacaagaag ataatggatg caccaataaa caaaaaagaa
    76321 gatatataca gatatgaatt aatgaagcct tttgaattta agtggaagtg tatgaatgtt
    76381 ccaatagttg ctagacagaa aggtggatat gatgtaatta tagcaagtga aatgttaggg
    76441 gttttatcgc ctaaggatat tgatgaaaag caaaaaaaga atataaatgt gttatctgct
    76501 gataaaattt ggggcacttg caaagaaacc atagaaaact ctataaatgc ttttataaaa
    76561 gaagggtatg atttaaacat taaggactat aaatattcaa tattattggc gaatccaaat
    76621 agtccttata caatattaag tgatggatac tggggtgatg gtgggattcc tggatatata
    76681 tttctatcat tggttcctaa tgaatatact atcaatagat taccagtatt aatagcacat
    76741 gaatgtaatc acaatattag atttcagttt atagagtgga ataataatat aacattagaa
    76801 gaaatgatga taaatgaagg tcttgcagaa aattttgcaa catggatgtt tggagaggaa
    76861 atgttaggac cttgggtcag tagaacagat atcgaaacat taaatactta tataaagcca
    76921 ataataaaaa gtgctttaaa agaaactgga tttcaaaata taacatctta tctttatggt
    76981 gatgatatag ctaaaatgca aggatatttt ccagtagggt tgccttattg tgcaggatat
    77041 gcttgtggat attatatgat taagtattat ttagaaaaga caaataaatc aataatcgaa
    77101 gcgactttat tgccttatag tgagataatc gaagcagtaa aagagttttg ggaataaatt
    77161 ttataaattg cataatttga aataaattat gcaattattt tatttttaag aaaaaataaa
    77221 ttgacaataa tttataagaa atatacaata atatatataa agaaatattt caatatttaa
    77281 aagttttaag atttcatatc tagagtagct aacattacat gttagtttct tgttacttat
    77341 ctaattactt tatatttcgt agttatatat aaaattacta taaaaaatga aatatattaa
    77401 acaatcaact gaaaaatgaa atgttaataa aaaaaaattc aaattataaa tattaaatga
    77461 atataattaa aacaaatata taaatttaag tataacactc acattttaat gtattgtgaa
    77521 atttttgttg aactttatgt accataactt ataaaattta tgtcatgtta tatttgaata
    77581 agtaataaaa ttgtagatgt aaattaatct acaaaattta tatgaaatgg agttgatgct
    77641 atgacagaat taatgattat aagtgggtta gtactattga tttgtataac ttctagcaag
    77701 gtattgtata aatttggagt accaatatta ttgattttta tcttactagg gatgttattt
    77761 gggtctgatg ggatggtagg aatctatttt gataactatg aactgacaaa acaattatgt
    77821 tctattggac taatatttat aatgtttttt ggagggtttg gaacaaactg gaatatggct
    77881 aaacctgttg ctataccttc tatattaatg tcttcactgg gtgtaataat tacggctggg
    77941 gttacaggta tgttttgcca catggtaata ggaactagtt tacttgaagg tttattaatt
    78001 ggggcaattg cagcttcaac agatgctgca tctgtgtttg ctgtgttgcg ttctcaaaaa
    78061 ctaaacttaa agggttcact tgcatcatta ttagaagttg aaagtggaag taatgaccca
    78121 atagcgtata tgctgacact aattcttttg acattgatga ataattctgg ggtagaactt
    78181 attgcaccaa tggtaataaa acaaatagct tttgggttag ctataggatt tatactagca
    78241 aaattatctg tttatatttt aagacattca aacttcgaga tagaaggatt ttatactata
    78301 tttataacag ctattgcaat actttcttat gcatttagcg agtatcttgg aggaaatgga
    78361 tatttaagtg tttacatttc aggtattatt ataggaaata gtaggatacc tcttaaaaaa
    78421 agtttggttc atttctttga tggaatttca tggattatgc aaataatgtt attctttatg
    78481 ttaggattgt tatctttccc ttctaagtta ccaaatgtat ttggtatagc aatggccata
    78541 tctatattca tgatagttat tgcaagacca ttagcaacat ttatagttct agcaaaattt
    78601 aaattctcaa ataaagaaaa attattcata tcgtgggtag gtcttagagg tgcggcttca
    78661 gtagtttttg caatttatgc tgttactcaa ggagtagcca tagagaatga catattccat
    78721 ataatatttt ttatagcgtt gctttcagta ggaatacaag gttcattgat accaactgta
    78781 gccagaaagt tggatttagt tgatgataat acacctgtat taaaaacatt taatgattat
    78841 gatggagaaa ttagctctaa acttatcgaa gtaaatgttg atgagggtaa taaatgggct
    78901 aataagagta taatagattc taatatacca gacgatatat taatagttat gataaaaaga
    78961 aaggaacagg ttttaatacc taaaggttca accattataa aaacagggga tattttggta
    79021 ttgagtggag atagaattga agaattaata caattataat ttattttgta ttgactttaa
    79081 cctaagggga aagtttaaac ttaaattaat caaatctaat gcgcaggtga tgagatgttt
    79141 tctataggaa tgttttctaa aataaataaa ataactacaa agacattaag gtattatgaa
    79201 gatatagggt tgttaaaacc agaatatgta gatgaattta caaaatatag gtattataca
    79261 acagagcaat tacctaaatt acatcagata ataactttaa aacaaatggg tttatcatta
    79321 gctgagataa aaaaagctgt agaaaatcct gaagaagttg aaaatatttt aatgaataaa
    79381 gaaaaagaaa tgttggatgt aattaaaagt gaagaatata aaataattaa actacgtaat
    79441 taccttatga atttgaaagg agaagtcaat atgaatgatg taattattaa gtctttacca
    79501 aaagttaaag ttgcttctat gagaaaagtg ttaaaggggt atgatgaact ttttaatcta
    79561 tttccaaatg taatggctga agaaatgatg aaaacagggt gtacatgtgc agttcctgat
    79621 tattgtttta atatatatca tgatggtgaa tatagagaga ctgatatgga tgttgaaatg
    79681 tgtcaagcta taaatgattt aaaggaagat acggatatat taaaatttaa agaattagat
    79741 gcagttgaaa atgcagtttg tatattacac aatggtccat attcaacatt aggaaaaact
    79801 tacgcagatg catttaaatg gatagaggat aataaatata aagtggttgg aaatcctaga
    79861 gaatcttata tagatggtat atggaataaa gagagtgaag aagactggtt gacagaagtt
    79921 cagataccag tgaaacgcat gttataatat gtctacaaag tataaataag aataaaaaag
    79981 gtggtgtctc aaagtaaaca ttttagttta tgagacactc tttttcatat gaaatcaagt
    80041 atatttttat aattacgatt atgaaaaaag gcttatctat atttttagac agcctcttat
    80101 ttttttatta taatagtttt ctaaagatgc tctatttata aatttttatt aaagacttta
    80161 taaataa
//
LOCUS       DAEHWO010000009        75053 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEHWO010000009 DAEHWO010000000
VERSION     DAEHWO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 75053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75053
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.009"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            156..539
                     /locus_tag="KNP54_000820"
     CDS             156..539
                     /locus_tag="KNP54_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBF0891744.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            541..891
                     /locus_tag="KNP54_000821"
     CDS             541..891
                     /locus_tag="KNP54_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891745.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(992..1450)
                     /locus_tag="KNP54_000822"
     CDS             complement(992..1450)
                     /locus_tag="KNP54_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891746.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLEEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1495..2283)
                     /locus_tag="KNP54_000823"
     CDS             complement(1495..2283)
                     /locus_tag="KNP54_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0891747.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQEGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2422..2859)
                     /locus_tag="KNP54_000824"
     CDS             complement(2422..2859)
                     /locus_tag="KNP54_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HBF0891748.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3681..4190
                     /locus_tag="KNP54_000825"
     CDS             3681..4190
                     /locus_tag="KNP54_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891749.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            4596..5132
                     /locus_tag="KNP54_000826"
     CDS             4596..5132
                     /locus_tag="KNP54_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBF0891750.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKK"
     gene            complement(5559..6359)
                     /locus_tag="KNP54_000827"
     CDS             complement(5559..6359)
                     /locus_tag="KNP54_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0891751.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(6554..8152)
                     /locus_tag="KNP54_000828"
     CDS             complement(6554..8152)
                     /locus_tag="KNP54_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBF0891752.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINTLESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            8480..8656
                     /locus_tag="KNP54_000829"
     CDS             8480..8656
                     /locus_tag="KNP54_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891753.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            8830..9960
                     /locus_tag="KNP54_000830"
     CDS             8830..9960
                     /locus_tag="KNP54_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBF0891754.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            10201..10551
                     /locus_tag="KNP54_000831"
     CDS             10201..10551
                     /locus_tag="KNP54_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBF0891755.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            10559..11008
                     /locus_tag="KNP54_000832"
     CDS             10559..11008
                     /locus_tag="KNP54_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBF0891756.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            11110..11685
                     /locus_tag="KNP54_000833"
     CDS             11110..11685
                     /locus_tag="KNP54_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBF0891757.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            11678..13087
                     /locus_tag="KNP54_000834"
     CDS             11678..13087
                     /locus_tag="KNP54_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBF0891758.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            13271..14704
                     /gene="eutA"
                     /locus_tag="KNP54_000835"
     CDS             13271..14704
                     /gene="eutA"
                     /locus_tag="KNP54_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBF0891759.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            14722..16086
                     /locus_tag="KNP54_000836"
     CDS             14722..16086
                     /locus_tag="KNP54_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBF0891760.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            16099..16980
                     /gene="eutC"
                     /locus_tag="KNP54_000837"
     CDS             16099..16980
                     /gene="eutC"
                     /locus_tag="KNP54_000837"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBF0891761.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            17000..17653
                     /gene="eutL"
                     /locus_tag="KNP54_000838"
     CDS             17000..17653
                     /gene="eutL"
                     /locus_tag="KNP54_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBF0891762.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            17664..18365
                     /locus_tag="KNP54_000839"
     CDS             17664..18365
                     /locus_tag="KNP54_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBF0891763.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            18368..19837
                     /locus_tag="KNP54_000840"
     CDS             18368..19837
                     /locus_tag="KNP54_000840"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBF0891764.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISD
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            19933..20220
                     /gene="eutM"
                     /locus_tag="KNP54_000841"
     CDS             19933..20220
                     /gene="eutM"
                     /locus_tag="KNP54_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBF0891765.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            20347..21108
                     /locus_tag="KNP54_000842"
     CDS             20347..21108
                     /locus_tag="KNP54_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBF0891766.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYRYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            21121..21750
                     /locus_tag="KNP54_000843"
     CDS             21121..21750
                     /locus_tag="KNP54_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBF0891767.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            21792..22517
                     /locus_tag="KNP54_000844"
     CDS             21792..22517
                     /locus_tag="KNP54_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBF0891768.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKEVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKV"
     gene            22530..22802
                     /locus_tag="KNP54_000845"
     CDS             22530..22802
                     /locus_tag="KNP54_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBF0891769.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            22795..23346
                     /locus_tag="KNP54_000846"
     CDS             22795..23346
                     /locus_tag="KNP54_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBF0891770.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            23358..24449
                     /gene="eutH"
                     /locus_tag="KNP54_000847"
     CDS             23358..24449
                     /gene="eutH"
                     /locus_tag="KNP54_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBF0891771.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            24451..24924
                     /locus_tag="KNP54_000848"
     CDS             24451..24924
                     /locus_tag="KNP54_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBF0891772.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(25044..25145)
                     /locus_tag="KNP54_000849"
                     /pseudo
     CDS             complement(25044..25145)
                     /locus_tag="KNP54_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            25440..25961
                     /locus_tag="KNP54_000850"
     CDS             25440..25961
                     /locus_tag="KNP54_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0891773.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            26340..27515
                     /locus_tag="KNP54_000851"
     CDS             26340..27515
                     /locus_tag="KNP54_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0891774.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            27550..29088
                     /locus_tag="KNP54_000852"
     CDS             27550..29088
                     /locus_tag="KNP54_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBF0891775.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            29120..30322
                     /locus_tag="KNP54_000853"
     CDS             29120..30322
                     /locus_tag="KNP54_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBF0891776.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQKKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(30489..31088)
                     /locus_tag="KNP54_000854"
     CDS             complement(30489..31088)
                     /locus_tag="KNP54_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0891777.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            31258..32616
                     /locus_tag="KNP54_000855"
     CDS             31258..32616
                     /locus_tag="KNP54_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891778.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            32609..33241
                     /locus_tag="KNP54_000856"
     CDS             32609..33241
                     /locus_tag="KNP54_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBF0891779.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            33570..34727
                     /locus_tag="KNP54_000857"
     CDS             33570..34727
                     /locus_tag="KNP54_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0891780.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(34874..35509)
                     /gene="lexA"
                     /locus_tag="KNP54_000858"
     CDS             complement(34874..35509)
                     /gene="lexA"
                     /locus_tag="KNP54_000858"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBF0891781.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(35613..36740)
                     /locus_tag="KNP54_000859"
     CDS             complement(35613..36740)
                     /locus_tag="KNP54_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0891782.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(37051..37896)
                     /locus_tag="KNP54_000860"
     CDS             complement(37051..37896)
                     /locus_tag="KNP54_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891783.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(37926..38297)
                     /locus_tag="KNP54_000861"
     CDS             complement(37926..38297)
                     /locus_tag="KNP54_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBF0891784.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(38450..38710)
                     /locus_tag="KNP54_000862"
     CDS             complement(38450..38710)
                     /locus_tag="KNP54_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBF0891785.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(38899..39843)
                     /locus_tag="KNP54_000863"
     CDS             complement(38899..39843)
                     /locus_tag="KNP54_000863"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBF0891786.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(39864..40718)
                     /locus_tag="KNP54_000864"
     CDS             complement(39864..40718)
                     /locus_tag="KNP54_000864"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBF0891787.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(40733..42094)
                     /gene="accC"
                     /locus_tag="KNP54_000865"
     CDS             complement(40733..42094)
                     /gene="accC"
                     /locus_tag="KNP54_000865"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBF0891788.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(42110..42562)
                     /gene="accB"
                     /locus_tag="KNP54_000866"
     CDS             complement(42110..42562)
                     /gene="accB"
                     /locus_tag="KNP54_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBF0891789.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(42832..43278)
                     /locus_tag="KNP54_000867"
     CDS             complement(42832..43278)
                     /locus_tag="KNP54_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891790.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            43553..43831
                     /locus_tag="KNP54_000868"
     CDS             43553..43831
                     /locus_tag="KNP54_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891791.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     ILVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(43960..44706)
                     /locus_tag="KNP54_000869"
     CDS             complement(43960..44706)
                     /locus_tag="KNP54_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891792.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGKAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(44835..45479)
                     /gene="trmB"
                     /locus_tag="KNP54_000870"
     CDS             complement(44835..45479)
                     /gene="trmB"
                     /locus_tag="KNP54_000870"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBF0891793.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(45617..45937)
                     /locus_tag="KNP54_000871"
     CDS             complement(45617..45937)
                     /locus_tag="KNP54_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBF0891794.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(46390..46638)
                     /locus_tag="KNP54_000872"
     CDS             complement(46390..46638)
                     /locus_tag="KNP54_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBF0891795.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVKDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(46669..47130)
                     /locus_tag="KNP54_000873"
     CDS             complement(46669..47130)
                     /locus_tag="KNP54_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBF0891796.1"
                     /translation="MKFGGVLLIVKDINKSKKFFEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQV"
     gene            complement(47168..48001)
                     /locus_tag="KNP54_000874"
     CDS             complement(47168..48001)
                     /locus_tag="KNP54_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891797.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSWMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(48275..48961)
                     /locus_tag="KNP54_000875"
     CDS             complement(48275..48961)
                     /locus_tag="KNP54_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891798.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(48976..51453)
                     /locus_tag="KNP54_000876"
     CDS             complement(48976..51453)
                     /locus_tag="KNP54_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0891799.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNTIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGNMNEEFIEDVRHMEGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGVTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(51672..53075)
                     /locus_tag="KNP54_000877"
     CDS             complement(51672..53075)
                     /locus_tag="KNP54_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0891800.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHVTLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            53574..54434
                     /locus_tag="KNP54_000878"
     CDS             53574..54434
                     /locus_tag="KNP54_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBF0891801.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(54673..55230)
                     /locus_tag="KNP54_000879"
     CDS             complement(54673..55230)
                     /locus_tag="KNP54_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0891802.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(55420..56307)
                     /locus_tag="KNP54_000880"
     CDS             complement(55420..56307)
                     /locus_tag="KNP54_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0891803.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            56426..57625
                     /locus_tag="KNP54_000881"
     CDS             56426..57625
                     /locus_tag="KNP54_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBF0891804.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(57819..60374)
                     /locus_tag="KNP54_000882"
     CDS             complement(57819..60374)
                     /locus_tag="KNP54_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0891805.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIEVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(60371..61057)
                     /locus_tag="KNP54_000883"
     CDS             complement(60371..61057)
                     /locus_tag="KNP54_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891806.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(61134..62042)
                     /locus_tag="KNP54_000884"
     CDS             complement(61134..62042)
                     /locus_tag="KNP54_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0891807.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(62044..62715)
                     /locus_tag="KNP54_000885"
     CDS             complement(62044..62715)
                     /locus_tag="KNP54_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891808.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            62977..64041
                     /locus_tag="KNP54_000886"
     CDS             62977..64041
                     /locus_tag="KNP54_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBF0891809.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            64199..64885
                     /locus_tag="KNP54_000887"
     CDS             64199..64885
                     /locus_tag="KNP54_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891810.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            64875..65906
                     /locus_tag="KNP54_000888"
     CDS             64875..65906
                     /locus_tag="KNP54_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0891811.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSRICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            65988..66653
                     /locus_tag="KNP54_000889"
     CDS             65988..66653
                     /locus_tag="KNP54_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891812.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            66666..69083
                     /locus_tag="KNP54_000890"
     CDS             66666..69083
                     /locus_tag="KNP54_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0891813.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(69264..70055)
                     /locus_tag="KNP54_000891"
     CDS             complement(69264..70055)
                     /locus_tag="KNP54_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBF0891814.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(70088..70675)
                     /locus_tag="KNP54_000892"
     CDS             complement(70088..70675)
                     /locus_tag="KNP54_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0891815.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIDLECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKSDWNLSI"
     gene            complement(70852..72243)
                     /locus_tag="KNP54_000893"
     CDS             complement(70852..72243)
                     /locus_tag="KNP54_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBF0891816.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(72427..73731)
                     /locus_tag="KNP54_000894"
     CDS             complement(72427..73731)
                     /locus_tag="KNP54_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBF0891817.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNNYY"
     gene            complement(74090..74965)
                     /locus_tag="KNP54_000895"
     CDS             complement(74090..74965)
                     /locus_tag="KNP54_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBF0891818.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDINTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
BASE COUNT        27718 a        10387 c        10509 g        26439 t
ORIGIN      
        1 atatagaaaa tccttataaa aatttaaatt gtaatgaata ggaagtaatt aaaaagaatt
       61 tttattgatt tttaaaaatt tagttagaaa ctatatcatt atggtaaaaa atgtattata
      121 atgtttagaa atattataat aaggagcgat taaacatgaa tctatcgaag aaaatagaag
      181 ataaaagaaa agctaaacag agagctgaaa aagttaagaa agctaaaatt gctacagctg
      241 gtgtggtatt aggagctgtt actggtgcag tgagtggagt acttttggct cctaaatctg
      301 gaaaagaaac aagagaggat ataaaagatg cttcacaaca aattgctgaa aagataaata
      361 tgaaaactgt agatgtaaaa ggcaaagtat ctgagaagct agaggataaa aaaggaaact
      421 ttatagaatc aaagaaaaaa ataaaaaaat atatagataa caaaaagagt gttgaaaatt
      481 ctagtgagga agataaaata atagatatag ttgaaccagt tagtgttact gaggaataat
      541 atggacaata caataacgat taacataagt ataatatatg tattattagc tatacttgct
      601 tgtattgctt tagtttattt aattattgta cttgttaaac tacataagat tttaaataat
      661 gttggaacta tgttaaatga aaatactcaa aatataaata caactttaaa taatcttcct
      721 aatgttgtag aaacttttgg agaagtagga gaaaatatga aagatgtaac agaagtagtt
      781 actgaagtta cagcagattt tcttgttact aaagacagtg tcaaatcaaa tatggatgtt
      841 atagttgata tattgactat aattaaaaac atttttctag ataaaaaata ataagtttaa
      901 ttaaaataag cctataagat ataatttaaa cgaccttaaa atagcattta taaggtcgtt
      961 ttttattagc ttgatttgac actatgtgtt tttaataatt ggtaatattc ctctttatca
     1021 tttgaacata tatatctatg cttgttgttt caattacatc cataagaaca tctttacatt
     1081 caagctcaaa atcttccatt ccttctaaat attcatcatc ttcatcaaaa aagatataag
     1141 aattatatag ccattcttca aatttttctt caagtatatc ccaatacgaa ctccaaaata
     1201 atccacaacc tgatatataa gatgctctac tttgatttat ataaacctcc tctagaagct
     1261 tttgtaatct actgctataa agaaaatctg ctcttccact gcttgatatt aattcattta
     1321 aatcttctat tgacattaat tcaactttac cacttttatc ataaggagta taattttcat
     1381 caacccattt atgtggtttg ttttctctgc atactgttgc tatcaactct acaacttttg
     1441 ttcttatcat ttttttatcc taacttattt attttttata aaataatcat gattttataa
     1501 tttatctatt tcttgtaatg ctaatttaac agtttcatat ctatcagcac catttattac
     1561 tacatcacct tttacaagtt tattagcttc tccacctaca acataaacct ttttacctaa
     1621 accttgctta taactagacg cttcaattat taaagaatct ttcaattgcc aatgtaaaat
     1681 ctgagcagcc actttatcag catcacctgt ataaacgatt acattttcat acactttatt
     1741 ttcccctccc tcttgagaat ttgatataga tttgtttagt ataccttctg ctatcaattt
     1801 agcaacttta tctttattat taacataata atctgtatct gctttactat ctacaaaaca
     1861 tacttctatt aatattgctg gtgcaatagt atgattaagc caataaagac ctctaacatc
     1921 agactttgcg cccctatctt tgaatactgt agctaaccta gtattcactc tttctgcata
     1981 ggttttgcca ttattagtct tatatattgt ttctgtccct actggagttg aagttgtggc
     2041 atttgaatta aaatgaatct gaacagccaa atcagtttcc tgtttatttg ctatagcaca
     2101 ttggtctgct aaatgattac ttgattcatc aactcttcct gtataaacag tagctccacc
     2161 tattttaagc catttaacaa ttaagtcatt cagtattctt gtttctttgc tttcgtttat
     2221 atacccaaca gctcctgtac cttttccaat taaagtgtgc cctggtatta ttactacttt
     2281 caaactaaca tctcctttac aattaaattt aacttctatt taatatatgc ataacctaga
     2341 attttgtttc tttttatatc ttatactttt attataaccc attttgtaaa aatatagaat
     2401 attaagtaaa taatgttaaa attataattt tgtatataag acattacttg attgcaataa
     2461 ttttatagca tattcatcta ttctatatcc agttctataa tatatatgtt taattccagc
     2521 ttgaattata gccttagtac aatttaagca aggaaagtga gttacataaa tagagcaatt
     2581 tttaactgaa ataccttctt ttgcacaata ataaagggca ttttgttcag cgtgaatggt
     2641 tctaatacaa tgtccatctc tcatttcatg accaacttca ctacaatgct tatctccaga
     2701 aatactacca ttatatccag tagacactat tctgttttct gaattgacaa ttatagctcc
     2761 tacataagct ctatcacaag ttcctctttc agctactgtt tcgcacagtc tcataaaata
     2821 ttcttgccat gagcatctat tttcaagttt tttattcaaa ttatatacct ccaaaactta
     2881 tatctaatat ataagattta taccttaaaa ataatattaa aaacaaattt atacgataaa
     2941 taaaatttat taatactgtt tttagtctaa attatttcat tttaaattaa agttacaagg
     3001 aatctaaaat tatatatatc tttcttcgta atattaatgt tacaatataa aaaactgtct
     3061 caataaaata gagacagttt tacagtcaaa gtttataata caagttcata tttttcttta
     3121 aattctttta cagcttcggg ccatgccttt tgttctgtaa tacctttttc tttagctatt
     3181 ttaattgcaa tctctcttat cattgcagcg ccttctaata ttcccatttt taatctccct
     3241 tcaaatatct ttttgtatag aatataaata gtgctaagat ttattacatg ctgcatatac
     3301 aatatctata caacacataa cttgtaaatt ccttttattt tcatacgtct ttaaccgaca
     3361 tataattata ttcaataagt tttaaaatta tgaactcaat tataattatt tttatttttt
     3421 tagaatctaa acactaaaaa ttgtaggtaa atttgtctta tgcctttata aatatttcta
     3481 cagttttaat tactggacat atctattttt attataaaaa gcgattaaaa atcgagaata
     3541 tccgcataaa aactgtatat aagcaaaacg gttaaaggaa aaagaagaaa tttacttgaa
     3601 tgttaaaatg cgttgcttga agcaatgggc agttttgcct ataatatcgg taacaactga
     3661 aagaaaggtg gttagcccta atgttaagcg aaaacattaa aacaatcagg aagtcaaaag
     3721 gactttcaca acaagaactt gctataaaac tgaatgtagt gcgacaaaca atatctaaat
     3781 gggaacaagg actgtcagtt cccgattctg atatgttgat ttccatatca gaggtgcttg
     3841 aaacgcccgt aagtacttta cttggagaaa ctattgttga gtcggaagtt gataacttaa
     3901 aagtgatttc tgaaaaatta gagattataa acttgcaact tgcacaaaga aaaaacatga
     3961 gaagaaaaat gtttcattgg ttatttattt tattatgtgc agtcatatta atagtttttg
     4021 tggtcttagg gggactaaat agtccttact tggattggaa ttataccgac cctgaaaccg
     4081 ctgtttttgg agtagctttt catgcttttg agtggctatt tgtcagatta gtaccgattg
     4141 tccttatagg agcaattatt ggaatctttt tgacacgtaa gaaaatatga agtaactctg
     4201 ctttttataa tacagcaagc gttccttaaa agcgtcattc tacatggcaa tcgaggacga
     4261 ctatgtaagg aagaaccttt ttgatttcca actaagcgaa gttattgagg acgacagtaa
     4321 gaccaaaacc gcattaagta aagtacagga agcaagactg ctggacttat actctcatgc
     4381 gtcagatgca ggaaatgcga ggtctggtag catgatttac aacgatttgt acaacgactg
     4441 ctagtagaaa taatatggag ataagtatta tctacaaagt cagaaaagaa atgacttgat
     4501 aatttactca tgttataatt attgatgtga aattaataaa tcgaaattcc ttttttggat
     4561 ttaataatac tgagtaagga aaaagtgaat tacttttgca aggaggtgtt aatatcaggc
     4621 aagtaaagtc ttttgttttt ccagttatat ccttaatatt cttagaccaa attagcaaag
     4681 ttcttatagg attattctta atggactttg aaattgatat aattgggaaa tttttaagat
     4741 tcaatcctgt tcaaaataca aatctctctt atgggggaaa ctttattggt attctatcta
     4801 atttatgggt attggtattg tttaacattt tagttatatt agttattata tctggatatg
     4861 ctttttataa atcaaaaaat gaacaaacaa gctattcagt aaaagtaatt atgtcttgtg
     4921 gacttgctgg tacaatatgt agcttgatag ataaattatt ttggggagga agtttagatt
     4981 ttttgcagat accaagcttt tttattttcg acttaaaaga ctgctacctt actgttgcag
     5041 aaataatatt tgttgtcata ggaattttgc ataatagaga aatatcaatg aaagaataca
     5101 tatatttttg ctatcgtcag tttaaaaaat aaatttagaa gataaattta agtttcaagg
     5161 taaacttatt taatcacagc aaatagttgg cttacttaag cttttgggct aaactgtgag
     5221 cactaattaa gtctctgata tctaacaaac ggagcacaaa aataaaaatt aaatataaag
     5281 cacagttaat tttgattaaa aagttgactg tcttttcttt tgtagaaatt taagcatagg
     5341 taataaagaa atgactgcat ttaagcatta tgtatataat tggaggcaat aaaaagccag
     5401 caaagcccat aaaatagagc tgtgctagca acatgatgaa ttataagaag ataatcaaaa
     5461 acttacgctt tattttaatt taaaaaaatg attactgtaa agaaatcatt ttttattata
     5521 atcactgata catcaaatat tctaaataaa atttttattt atctggaatt gtatattttt
     5581 tctataatat taactacagc gtacattgcc caagcacaga tagccaatac aaatactccc
     5641 atcattacta aatctaattt aaatacttga gaaccatata ctatcaagta gcctattcca
     5701 tatcttgaaa ctaaaaattc tccaactatt acacctaccc atgccatacc aatattaatt
     5761 ttagttaaat ttattaaatt tcctgtgttt gcaggtaata tgagtttaaa taatatttga
     5821 gatttagtag ctccaaaact ttttaacatc ttaatttttt cttcatctat attcataaaa
     5881 taattataag ctgaaagtat agtaacaaca acagaaatcg ttacagctgt tacgacgatt
     5941 ccttctattc cagcacctac ccaaactata attataggag ctaaagcagt cttaggaaga
     6001 gcatttaaaa ctaccaaaaa tgggtctaat atttttgata atttttctga ccaccaaaga
     6061 gcaattgcta ccaaaatacc taatacagta cctataacaa gaccaagaac agtttcatat
     6121 acagatattc caatatgttt aaataattga ccactaaatg catattgaat aaataaattg
     6181 taaatatcac ttggtttgct aaatagaaat gtatttataa catttaagtc agctaaaagt
     6241 tcccagatta caataaaacc aattaaaatt aatagctggt agaataatac atttcttttt
     6301 tctcttttta cacctttaac atagtttata tatccttcag atcttttatt aagcctcatg
     6361 tgtatctagc tccttccata atatgtcgaa atacttttga aaatcaggaa ctttacgtgt
     6421 tttgagaggc gtttttgttc catccatgtt aagttcaata tcgtaaatat tttttatggt
     6481 agctggtctt ttagatagta ttgcaacctt atctgatatg cttattgctt ctgctatagc
     6541 taaaaaagtg caactaattg cttaaagaaa cagaattatc aacttcagca cccatataaa
     6601 caatattaag atttcctaaa ctgctatccc aaacgatact attaataata gtagataata
     6661 acaatctctt atcatctaaa ctggcattat caacttcatc attaaatctc ttcaaattac
     6721 taacaataat atcaatatta atactgtcac tactaatatt gatgttacta gattccaaag
     6781 tattaatctt atcctttaaa atactaatct cattatttag gctctcaatc tgggaaacta
     6841 tataatcaga agcagtacta ccagtatttt ttgcaagctc tataactaaa tttttaataa
     6901 gtctttcctt atctaaaatt tgatttttaa gtaaattagt ctcagattta aaaatattaa
     6961 aaacattatc agtcttaatg ttattactat tgaatgcact tataatagac tcttctttac
     7021 aattcttaat tttatctata actaaacttt caactaatgg accattaaga tttttacagt
     7081 tgcaactatc agacccaagt gtttttttag taccacaaat ataataatac tttaaatcct
     7141 tgtcagtttt tttgccttta taggtaattc tcatattaga accacattta ccacatttta
     7201 taagaccaga taaaagagca gtttttccag ttgatatcct tggagtttta tcacgatttt
     7261 tatctaattg attttgtact tcaagccata tttcaggttc tatgactcca tggtgttttg
     7321 caattgctgc tattgagtta gatgtatttt tagcataggt aaggattcca cattttctat
     7381 ctggagtacc tacaacatcc ataccactat ttttaaggta atctaaaatt tcatcattag
     7441 cttttacata tgctggattt ctaagtattc tagataaaga actagggtca aatttgccac
     7501 cacgaggacc ccttattcca ttattataga catatttata taacttagat aaggacctaa
     7561 gttctaaata tttattgtat attagcttta caatctccat ttgttcatca tttacttgaa
     7621 gcttatacat acttctttct tttagatttt catctaagaa tgtgattttt tcactgttga
     7681 atccatgagg tgtattgcct ccaagccatc taccactacg ggctaattca tacatattgt
     7741 cttttatacg ttctgctatt gtttctcttt ctaattgagc aaatacactt gatataaaca
     7801 tcatagctct tcccattgga gttgaagtat caaattgttc tttgatagat ataaatgata
     7861 tgcttagttc atttaatttt tctattaaag tagagaagtc agatacattt ctcgatatcc
     7921 tatctaatct ataacaaact aggtaactaa atttcttatc tttggcatcc tgcatcattt
     7981 tcttaaattg tggtctatct atattgctac cactaaatcc ctcatcttca tatatcaaaa
     8041 aatcttttac accaatagac tttgcataat caatacataa ttgtatttga ttttctatag
     8101 aatcaccttt tccagtaaat cttgattttc ttgaataaat tgcagctttc aaaattaaaa
     8161 ccccctataa gttaggatat atatttgaaa ctatttatct acaacctttt aagtaaactt
     8221 attagaatga atttattaat taggtaaatt tatataattc tactttttat aatatatgac
     8281 tatttatttt atttctttac tattcaagtt ctaaatcaat aataaatttt gatatttaat
     8341 tgtatcagga caaatctcta atttcataga ttattaatat aaaatcatag gttagtgtga
     8401 aaaagttgaa atttaaatat tttaaaagat aatttttttg aactaatagg tataacaaaa
     8461 atttataggg ggattgcata tggaaatcaa tgttatagaa attttcccta aagataaagc
     8521 taaacttaat aaaatagaaa tggataaagc tagttggttt gtaaatataa taagtaaaaa
     8581 atatcctaaa gaagctttaa atgaagcatt tagtacttta gaaaaagaat taaatataag
     8641 taaagctaat acataagctt tgattattga ttttatatac tattggtttt atacgctatg
     8701 acttgacatt atattaatca aatagtatat ttttaaatat agcacaatga agtgttaaaa
     8761 gagcaatgga gctccataga taaagtctat ggagcttttt tgcgtattta acttaaggag
     8821 gataggactt tgaataactt tgagattaaa actagaataa aatttggaga aggctcacta
     8881 aaagctttgc aagaattaaa aaacaaaaat gtactaataa taacagaccc ttttatggtg
     8941 aaatcaaaaa caatagataa aataacatct aatttaataa actcaacata tcaagttttt
     9001 gaagaaatag taccagaccc accaatagaa gtagtagtag caggaataga agcatttaaa
     9061 tctataaatc cagacgtaat aatagcatta ggtggtggtt ctgcaataga tgcagcaaaa
     9121 tctataatgg acttttctaa aaaaatatta aaaattaacg aagtagagtt tatagcaata
     9181 ccaacaacaa gtggaacagg ttcagaagta acatcatttg ctgtaataac agatagtcaa
     9241 aaaaaatgta agtatccatt agtgagtgat gatttacttc cagatatggc aatactagac
     9301 ccagaacttg taaaaactgt accaaatttt ataacagcag atacagggat ggatgtattg
     9361 acacatgcta tagaagctta cgtatctaca aattctaatg acttttcaga tgcactagct
     9421 gaaaaagcta taaagttagt atttaaatac ttaataaaag catataaaga tggaaatgac
     9481 atagaagcta gagaaaaaat gcacaatgca tcttgtttag caggtatggc atttaaccaa
     9541 gcatcacttg gcataaatca ttctattgca catgtattag gtggaaaatt ccatatacca
     9601 catggaagaa caaactctat attacttcct catgtaatag aatataattc atcaatagta
     9661 ggatatacta acacaactta ctctgctaca gctaaaaaat atgcacaaat agcagaatta
     9721 gtaggacttg ggagtgctaa tataagaata tctgttagaa atttagtaaa tgaaataaag
     9781 aaactacaaa aagaaatgaa tatgccaact aaattgacac aatgcaaatt aagtttagaa
     9841 gatataacta atgaagaaag agaaatagca aaacttgcta taaaagatac ttgtacatta
     9901 actaatccta aggtaccaac tgaagatgat ataataaaca tattaaagaa cattaaataa
     9961 ctacatttta ttacatgtaa atataatatt atacaaatag ggaaaatgtt tttaaaaata
    10021 taaattatat attgacaaat ataaaacata aaactataat gaaagtatca caaaggcgtg
    10081 atactttagt agaaagcaat ggagcttctt aggaatatta atattattct tatggagctc
    10141 cttttatttt aatcaaatag ctttttaata aactatattc aaagaaagca gggaataaat
    10201 ttgactgaag aatctaagca aagagttatt caagaatatg ttcctggaaa acaggttaca
    10261 ttagcacata tcatagctaa ccctaatgaa gatatatata agaagttagg attagtactt
    10321 gataaaaaag atgcaatagg aatacttaca ataacaccaa gtgaagcgtc aataatagca
    10381 gcagatgttg ctacaaaggc ttcaaatgta tctttaggtt ttatagatag atttagtggt
    10441 tcagtagtaa tatcaggtga tgtaagttct gtagaatcag cgttaaatga tgttttagaa
    10501 gtcttaggaa atatgttaaa cttctcatct acaaaaatca caaggacata ataatacaat
    10561 gaagaatata atatttatgg gaaagacagg tagtggtaaa actaccttat gtcaaaaact
    10621 agaccagtta gaattaaagt ataaaaaaac tcaatcagtg gaactttata ataatgcaat
    10681 agacactcct ggtgagtata tggaaaatag aaacctatat aatgccttaa taacaacatc
    10741 agcagatgct aaaattatag caatagtgta tgatgccaca caagaagaaa attatatagc
    10801 accaggtttt gccagtatgt tttgcaaaga cgtaatagga attataacta aaataaataa
    10861 agctactgaa aacgaagtca atatagctta tgaaagacta tcactagcag gagcaagtca
    10921 aatctttaaa atagacacag ttgataatat tggacttgaa aaattattta aatatctaga
    10981 aaaatataaa aatatagatg aagtttaagg ggaaatattt ttttattcaa aaatattatt
    11041 aaagtatgat aaaataaaaa aatgtataaa ctattttaag aagatttaat ctttaagcga
    11101 ggtaggaaca tggggaaaaa aatactattg gttgatgatg aaccactgtt aaggatggat
    11161 acaaaagata tattagaaag tcatggctat gaaataatag gcgaagcaag tgatggattt
    11221 gaagctgttg aaatgtgtaa aaaacacaaa cctgatttag ttataatgga tatagagatg
    11281 ccaatacttg atggtataaa ggcaggcaaa ataatatgta aagaaaatat agctggtgga
    11341 gtacttttat taacttcatt tgaagataaa gaatacgtag aaaaggctaa aagtataggt
    11401 gcttatggat atttagtaaa aacagcaagt gaaaaatcac ttatcccaac catagaaatg
    11461 tgtttaaata aggtaaatga atttgaaaaa atgaaaaaag atttagaaaa agtaaattct
    11521 aaattgaatg aaagaaaatt agtagaaaga gcaaaaggta tacttataag agagtttaag
    11581 atttctgagg atgaagcata cactagaata agaaaattaa gtatggataa aagaactaca
    11641 atgatggaaa ttgccaaaat gattataata ggatacgatg actaatacga taaaaaaaat
    11701 atcaactgca caaacatact taaataataa cgaaattgaa aaaattatag aagtatcaaa
    11761 atccttagat ttaatggctt ctttttatga agctgatgtt tttatagatg tactaagtaa
    11821 atttgatgat gaagcaattg ttgtggcaca tggtagacct aaagaaaagt caatgtactg
    11881 tgaaaatgtt ataggtaaaa aggctttaat tgaaaatgaa ccaggagtta taaagtgctt
    11941 aaaaacagga gaaagagtaa gagatattaa agctttaaca caggaatata aactggtcaa
    12001 acaaaatatt cagccaataa cactagatga caaagtttta gcagtactaa tagttgaaaa
    12061 agatataagt agtgaagtta agaatgagtt taatgctagt gaagacgaag aaaataaaaa
    12121 tttacatcag tttataaaac ttattggaaa taatgacttt ttagttgata atttaaattc
    12181 agccatatta atatttgata aaaatggaaa attaaaaatt aaaaatcgta ttgcaactga
    12241 gatatacaaa aatcttgggt ttggatatga tatacaagat atgcattaca atgatttaga
    12301 tatagaaacc aacacctttg aaaatatatt aatggatgaa aattatgatg agacaaatga
    12361 agtttcaata ggtaatatgt tttttaaaat aaagaccata tacatcaaag atgatgaatt
    12421 taaggtttgc aaaatagtac aagatataag tgatttaaag agaaaagaag aagaattagt
    12481 tttgaaaaca gtggctataa gagaagctca tcatagagta aaaaataatc ttcatacagt
    12541 aatatctata ataaaaaaac aaagtagatt atctcaaaat gatgaagtaa agcagtgttt
    12601 agataacata ataaataggg tatttgcaat actttcgact cattatttac tatctaaaga
    12661 agttgataat aatatatcta tacgagaagg tatcaattta ttagtgtcaa atattcaagg
    12721 tggctattta tttagtaagg atatagatat acgtataact ggtgaagatt ttaaaattag
    12781 tggagaaaaa gcaacagcaa tacttttggt tataaatgaa atactacaaa attgttatga
    12841 ccatgcattt tcggatagag aacatggtac tatacaaata ttaataaata aagataacga
    12901 ctatagaaat attgctatta tagatgatgg aattggattt gatagtaata atataaataa
    12961 aaatagctta gggacatata taatagatag ttatataaca cagatgttaa aaggaaatat
    13021 agagagaaaa agtagtgaga atggtacaga agtattaatt actataccta cacaaattaa
    13081 tatttaaata ataactcatc tacaaagtag tagttttaat tgagcaaaga ggcttaaggt
    13141 tattaataga ttaagttaat tgaatgtatt tataaaaatt ataagtatat attcaattta
    13201 acaggtattt attataactt taagcctctt tgcttgttta agacatactt aaattttagg
    13261 aggtgagaaa atgagagaag agttattaag tgttggtatt gacattggaa caagtactac
    13321 tcagttaatt ttttctaaat taatagtaga aaatactgaa tcaaattttt cggtacctag
    13381 aataagtata gtagacaaag aaattattta taaaagcaaa gtttatttca cccctcttat
    13441 ttcaaataat gaaataaatg gtcaacaaat aaaagatata gttgaaaatg aatataaaaa
    13501 agcaaatata tctaaagaag atatacatac aggagcagta ataataactg gtgaaacagc
    13561 tagaaaagaa aatgcaaatg atgtacttca tactttgagt ggatttgctg gggacttcgt
    13621 tgttgcaaca gcaggacctg atttagaaag tataatatca ggaaaaggag ctggagctca
    13681 tatttattca aaagaacatt caactacaat tgtaaatata gacataggtg ggggaactag
    13741 taacatagcc tcatttaaaa ggggagaagt aaccgatact gggtgtttgg atataggtgg
    13801 aaggcttgta aagatagata aaataagtaa aaaaataact tatatatcac ctaaaataga
    13861 taaaatcata aaagataata atttaaatct tcaagtaggc acaatggcta ctgtagaaaa
    13921 tacaaagcca atagtggata taatggttga cttattaatg gaaagcatag gattaaagaa
    13981 acagacacct ttgtttgatt ttataataac caataaatca ataagtatag atgaaaatat
    14041 taaaaatgtt tcattctctg gtggagtagc tgattatatt tactatgatg gagaaataaa
    14101 agattatttt gaatatggtg acttgggaat tttacttggg caagcaataa aaaattgtga
    14161 ataccttaaa aaagtaaatg tagttaaatc tatggaaaca ataagagcca cagtggttgg
    14221 agcaggttct catactactg aagtaagtgg aagtacaata acttacacta gcgaaaagtt
    14281 tccacttaag aacttgccag ttttaaaatt atcaattgat gaagaaacag gcacttcaaa
    14341 acaaatcagt gaagctataa aaaataaact taattggttt aaactagaaa atgatttaca
    14401 gaaagttgct atagccatga taggaaagaa aaatccaacc tttttagata tacaagagta
    14461 tgctaaaggg tttgtagatg gaatgcaaca aatcatagaa aatgatttac cttttatagt
    14521 aattgttgaa aatgatatgg caaaagtgtt aggtcaagca atatatgcat tattaaatta
    14581 tgaaaaagaa attgtttgta tagacagtgt caaggttgaa aatggagact atatcgacat
    14641 tggaaaacct atagttgaag gtaaagtttt acctgtggta ataaaaacat tagtttttaa
    14701 ttaatagaag gaggtaagta aatgatttta aatacaaaat tatttggacg tacttatcag
    14761 tttaaaggct tatatgatgt aatggctaaa gctaatgaag aaaaatcagg agataaatta
    14821 gcaggtcttg cagcagaatc agctgaagaa agaatagcag caaaagttgt tttatcacac
    14881 ataaaattgg aggatataag aaataatcct gcagtggcat atgaagaaga tgaagtaaca
    14941 agaataatac aagatgctgt aaatgaaaaa gtttatgaag aaataaaaaa ttggacagtc
    15001 tctgaactta gagaatggct attggattca aatactacaa gtcttgatat aagaagaata
    15061 tcaagaggat taacttctga aatgatagca gcagttgcaa aattaatgtc aaatatggac
    15121 ttagtttatg cagctaaaaa gataaaggtt actgctcact gtaatacaac tataggagaa
    15181 caaggaacat tatcagcaag acttcaacct aatcatccaa cagacgaccc agatggaata
    15241 cttgcatcac ttcttgaagg tttaactttt ggtataggag atgcagtact tggattaaat
    15301 ccagttgatg actctgttga gagtgttact aaagtattaa aaagatttga agaagtaaaa
    15361 caaaaatatc aaataccaac tcaaacatgt gtattggcac acgttactac acaaatggaa
    15421 gcaataagaa atggtgctcc tgcagattta atattccaat ctatagcagg ttctgaaaaa
    15481 ggaaatgaag catttggatt taatggcgac actatagaag aagctagaca gttagcctta
    15541 aaacacggta cagctacagg acctaacgtt atgtattttg aaactggaca aggttcagaa
    15601 ttatcttcag aagcacatca tggaatagac caagttacta tggaagctag atgctatgga
    15661 tttgctaaaa agtatgaacc attcttagta aatacagttg ttgggtttat aggacctgag
    15721 tacttatatg atgctagaga agttgtaaga gcaggacttg aagaccactt tatgggtaaa
    15781 ctacatggct taccaatggg tgttgatgtt tgttacacta accatatgaa ggctgaccaa
    15841 aatgatatgg aaaacttagc catactatta acaacagcag gatgtacgta ttttatggga
    15901 atacctcatg gagatgatgt tatgcttaac tatcaaacaa caggatacca tgaaacagca
    15961 tcacttagag aaatgtttgg actaacagca ataaaagaat ttgatgcttg gatggaaaag
    16021 atgggattct ctaaagatgg taagttaaca gagttggcgg gagacgcatc tgtattatta
    16081 ggataggagg tatttaatat gaatgagaag gatttaaaag cattggtaga acaattagtt
    16141 ggacaaatgg ttggagaatt agatactaat gttgtgtctg agactgttaa aaaggcaact
    16201 gaagttgtag tagacaacaa tgcttgtata gatgatataa cagaagttga tataagaaag
    16261 caattactag taaaaaatcc taaggatgca gaagcttatt tagatatgaa agcaaaaaca
    16321 cctgcaagat taggtatagg aagagctggt actagatata aaacagaaac agttttaaga
    16381 tttagagcag accatgctgc tgcacaagat gctgtattct cttatgtaga tgaagaattt
    16441 ataaaagaaa ataatatgtt tgcagtggaa actttatgta aagataaaga tgaatactta
    16501 acaagaccag atttgggaag aaaattttct ccagaaacta taaataatat aaaatctaaa
    16561 tttggtacaa atcaaaaggt tttaatatta gttggagatg ggcttagctc agctgcaata
    16621 gaggcaaatt taaaagactg tgtgccagct ataaaacagg ggctaaaaat gtatggtata
    16681 gattcaagtg aaattttatt tgttaaacat tgtagagttg gtgctatgga ccacttaggt
    16741 gaagaattag gttgtgaagt tatatgtatg ttggttggag aaagaccagg attagttact
    16801 gctgaatcaa tgtcagcata tatagcttat aagccatata taggaatggc agaagcaaaa
    16861 agaacagtta tatcaaatat tcacaaaggt ggaacaactg cagttgaagc aggtgctcat
    16921 atagctgaac ttataaaaac tatgttagat aaaaaagctt caggaataga ccttaaataa
    16981 agtcgaggga gtgtagaata tgaaaaatga tgtaattcgt cctaatatac taggaattaa
    17041 aataatttca aatataagtc cagaaatggc acaaaaacta gaattaaaat cacatcacaa
    17101 aagcttaggt ttaataactg cagactgtga tgatgttacg tatacagctc ttgacgaagc
    17161 aactaaagct tcagaagttg atgttgtata tgcaaaatca atgtatgcag gtgctgcaaa
    17221 tgcttcaaca aaacttgctg gtgaagtatt aggaataata gcaggtccaa gcccagcaga
    17281 agtaagaagt ggtctaaatg cagtagttga ttttctagag tatggagcaa cttttataag
    17341 tgcaaatgat gatgattcaa tagcatacta tgctcactgc gtatcaagaa caggtacata
    17401 cctttcagag gtagcaggaa taagagaagg tgaagcatta gcttatttag tagcaccacc
    17461 acttgaagca atgtatgcac tagatgcagc aatgaaagct gcagatgtta agatgtgtga
    17521 attatttgca cctccaactg aaacaaactt tggtggagca ttacttacag gttctcaatc
    17581 ggcttgtaaa gcagcatgtg atgcatttgc agaagcagta aaatcagttg cagacaatcc
    17641 aacaggattt taaggatagt tagatggatg ctataggctt aatagaagta ataggatatg
    17701 ttgctgcaat agaagcttct gatgcttgtt taaaatctgc aaatgttaat attgtaagag
    17761 ttgataaggt tggagcaggt attgttactt taacaatatg tggagatgtc ggtgctgtaa
    17821 aagctgcttt agaagcaggt gaaatagcag cttccagagt tggtacatta agaacatcac
    17881 atattatacc gagaatccat aatgaagtaa caaatgcttt attcaaaact aaagaaccta
    17941 aagtctgtga agtttcagaa gataaagaaa aaaactttga gattacattg gaaatagctg
    18001 ataatgtatc gaaaaattta tcagaaaaag aaaatgtaat tttagatgtc aatgaaaaca
    18061 gtggagatac tgaaaattta tatagtgata tagataaaac aaacaaaaaa attgaaacag
    18121 ttgatgatag tttaacagaa gctaatgagg aaaaaataga aaacactaat gataaagaag
    18181 tattggaaca agttaaaata gaaaattccg attttgatag agatgaccta tcaaagaaca
    18241 gtgtaaaaaa acttaaagct atggctaaga aattagattc ttcaataact tataaagact
    18301 taaatgttct taaaaaagaa gaattaataa acttagttaa aaagcttagt agaagggata
    18361 gatagttatg acacttttag ataaagattt agtatctata caagaagtaa gaactcttgt
    18421 aagaagatct aaagtggctc aagagaaact ttctaaaatg agtcaagagc aaatagataa
    18481 aatagtaaaa gctgttgtag atgcagcatt taataatgct actaaattag ctaaaatggc
    18541 aaatgaagaa actggatttg gaaaatggga agataaagta attaaaaata cttttgcatc
    18601 tatgggagtt tatgaaactt taaagaacac aaaaactatt ggaataattg gtgaagataa
    18661 agaagccaat acgatagata tagctacacc agttggagtt gttgcaggtc ttataccttc
    18721 aacaaaccca acatcaacag taatatacaa aactataata tctctaaaag caggaaatac
    18781 tatagttttc tctccacatc caaatgcaaa aaactgcata cttgaaacag ttaatataat
    18841 aagtgatgct gctataaagg ctggagctcc agaggattca atattatgta taactaatcc
    18901 aagtatagtt ggaaccaatg aattgatgaa acataaagat acaaacttaa tactagcaac
    18961 tggaggagaa gcaatggtta gagctgctta ctcttcagga acaccagcta ttggagttgg
    19021 accaggaaat ggaccagcat ttatagataa atcagcaaat gttaaattag caatcaaaag
    19081 aataatagat tctaaaactt ttgataatgg tgttatatgt gcatcagaac aatctatagt
    19141 aatagaaaaa tctatggaag aaactgtttt aaaagagctt aaaaatcaag gtgcatatgt
    19201 tttaaatgag gaggaaagtg aaagattagc aaaattcata ttaagagcta atggtactat
    19261 gaatccacaa atagttggta aaagtgttga ggtaatagca aatttagcag acttaacaaa
    19321 tgtacctaaa aatacaaaag ttctagttgc aagagaaaat aaagttggtc acaatgtagc
    19381 ctattcaaga gaaaaactta caccaatact agcgttctat gttgaagaaa atgtagaagc
    19441 tattatgaac agatgcagag aaatattgtt aaatgaaggt gcaggtcata cattctcaat
    19501 gcatgtaaat gatgaagaat tggtaaaaag atttgccctt aatatgccag tatcaagaat
    19561 acttgtgaat actccttcag cacttggagg aataggtgca tcaacaaacc ttgtaccagc
    19621 actaacactt ggttgtggtg caataggtgg aagttcaact tcaaacaata taggaccact
    19681 tgatttaata aatgttaaaa gagtagctta tggaatcaaa gaaatagaag aacttggaag
    19741 agataaatct caagttgaaa aatcaatgtt tgactcaatg gataaagaag aattaataaa
    19801 tcttcttgtt caaaaactag tcaaagaact agcataacta aaataaacaa tgaaacttat
    19861 ggctatcgct ataaatttct aaaaatataa actataaaaa actataaaat taaatttttg
    19921 gaggataaga ttatggcaag tgcaaacgca ttaggaatga tagaaactaa aggattagta
    19981 ggagcaatag aagcagcaga tgcaatggtt aaagctgcaa atgtacaatt agtaggaaaa
    20041 gagcaagtag gtggaggatt agttactgta atggtaagag gagatgttgg agctgttaaa
    20101 gctgctacag atgcaggagc tgccgctgcc gagagagttg gagaactaat atcagttcat
    20161 gttataccaa gaccacactt tgaagtagat gctatattac caaaggtatc agctgagtaa
    20221 tataagaata attataaaat ttaaattttg attgaaaaag aggctatctc aaaaatgagt
    20281 cttactaata aactcaatgt attttgaggt agtctttttt atacatctaa taggagatgt
    20341 gataaaatgg gtgttttaac agaaaacgaa gtaaaaagaa aaattggaaa aaacaaaaat
    20401 aatataactg aattttatat agaaaaaggt caaataataa ctccttctgc aaaatcttat
    20461 ttagctgaga gaagtattga gcttaaatat gttgataaac tttcagatgt aaacaatgaa
    20521 cctaaagaag ttgtaaaaga agtagttaaa gagaaaaaat atagatatac tactgtattt
    20581 ggcgctaaat tggatgaaaa accagaacat atgactcaat taaatggaaa tcttttagtt
    20641 tttaaagacc ataaaagaat aatattgaga ggaaaaatag attctcttga atcagaaata
    20701 ctaaaggtac agatactttg tcagaaacta gatatgccaa agcttgttaa ggaattgcaa
    20761 gaagtattag actttgtaag aaatataatg agatgtgaag ttttagatga aaagctaggg
    20821 gactttaaac ttttaggatt aactcctcaa gaacttagag aacaatctca ctatcctaaa
    20881 aaatactttg gtataggaca tgagttccca agttatgaaa tgggagaagt agtagtagct
    20941 ataaatagta taagaagtaa tacacgagag gttgaacttg cagcctatga agcatttaag
    21001 ggtgagtatg gaaatgttca cagagaagat ttaataaagg cacttaatag attatcgtca
    21061 gtattttgga taatgatata taaggttaga actaataagt ataagtagtt ggaggacata
    21121 atggagaatc tattaaatga aatagtggaa gaagtaataa ctagagttaa aaaagaagca
    21181 tttatagaag ttgaagcatc aggaagacac gttcacttaa gtagagaaga tgtcgataaa
    21241 ttatttggag aaggatatac tcttacaaaa ctaaaagacc tatctcaacc aggtcaatat
    21301 gcatgtaagg aaagagttac aataactggt cctaaaggaa gtataaaaaa tgtagttgta
    21361 cttggaccat gtagaaatga aactcaggta gaaatatctt taacagatgg ttcaactctt
    21421 ggactaaaag ctcctataaa acaaagtgga gacttagaag gtactttaag tattaaaata
    21481 tcaacacaat atggtgaagt tgaacttgat aaggggttaa tggttgctaa aagacatata
    21541 cacatgactc ctaaagatgc tgaaaaattc aatgtatgtg ataaagagat agttgaagct
    21601 aaggtgatgg gtcaaagacc tttaacattt gatgatgtag taataagagt gagtgacagt
    21661 tttaaaactt atatgcatat agactatgat gaagccaatg catgtggtta ttcaaaagga
    21721 actgttgcta aaataataaa gaaagcgtaa atttaaccta ctatataaat tacctctagg
    21781 gaggatttaa tatgaattat gataaccttg tagatttaat aacggaagaa atctataaaa
    21841 aaataaatag taatgaaata aaaatatcta ataaacctaa agctgtgatt gtatttgaac
    21901 aagataacaa taaatttaac ttattaaaag atgaatttga aatagtagaa tttgataaaa
    21961 gtataaggga atgtgaaata gtgatagttt caagactttg tatgaggggg ctatcgaata
    22021 tagcacttgg aaattcaaca agtgatgaag aaagatttat actaaaaatg attatgaagg
    22081 gcaaagaagt atatgtccta gatgaaggaa ttgaatacaa aaaatataag gatactgcac
    22141 caaaagcatt atataagaaa tttatgtcat ttgaagatga aatatgtaaa tttggtgtag
    22201 aaattataaa agacttaaat gttataacta aaaataagtt aaatataaag aaagaactag
    22261 aaagtactag aggttctaaa aaagaagata caaaagtttt agataaagat gttttaaatt
    22321 taaccagtgt agaaagtgta aaaatagata atgaatttag tttagattta aggaataaaa
    22381 aacttatatc ggaagctgac ttaagaaaac caactataaa tggagttaaa aacatattag
    22441 ttaataaaaa aagtataata acaccattag ctgtagattt tatgagaata caccatctca
    22501 aactaaagaa agtgtaagga ggtaatttta tggatatagg aaaagttgta ggtaatgttt
    22561 gggctacaag aaaagatgaa aaattatgtg gccaaaaact tttagttgta aaaattttaa
    22621 aaactaaaga cacatacaag gaaggcttca tggttgcagc cgataatgca ggagcaggaa
    22681 atggagactt agttcttata tccaaaggtt cctcagctag agagtcgatt gaaaaatctc
    22741 atgttccggt agatgcaact atagttggag tagtcgattc gtttgaggtg tttgatgaat
    22801 aaaagtatag gagctataga gtttaaaagc attgctaaag gtatagaagt atccaatgaa
    22861 atgataaaga aatcttcagt tgatgtattg tacttaaaaa gtatttgccc aggtaaattt
    22921 ctaataatag taggtggaga aacttcttat ataaatgaat gtgtagatta tggaataaaa
    22981 cttggagaag gatatattgt agataacttc gtaataaatg caatttcaca agaaatatta
    23041 gatggattta aaaataagta tcaaaagcta gatagtatag tctctatagg cgttgttgaa
    23101 agtagtaaag tatgcgctgg aataaaaatg cttgataaga ctttaaaatc tggcgactta
    23161 gtattagtaa aacttcaatt atcttttgct ataggtggca aattagtata tatagtagca
    23221 ggagatttaa gtagtttaga atatgcatta aaagaaagtg aaaatgtagt aagagaaaaa
    23281 gaagtaatat ataagactgt aataccatca gtagacagtc aaataataaa aagtctaata
    23341 aaataatggg gggaattatg agtataaacg aaattataat ctatgtaatg gtagtcttca
    23401 tggtacttgg agctatagat aaatgtatag gtaacaaatt tggtcttgga gaacaatttg
    23461 aagaaggtat aatggcaatg gggtcacttg cagttgcaat ggttggtgtt atatgtttag
    23521 caccagttct tgctgatgta ttaagaccaa ttgtagtacc agtatttaat atacttggag
    23581 ctgacccagc tatgtttgct ggaagtttat tagctaatga tatgggtggt gcaccacttg
    23641 cacttgaact tgcgaaagac cctaatgctg ggttatttgg tggattaata gtaggggcta
    23701 tgatgggacc tacaatagta tttataatac cagttgcgct tggaataatt gaaaaagaag
    23761 accaaaaatt cttagcaaca ggaatacttg caggtataat aacaatacct attggagcat
    23821 tcgttggtgg attagttgca ggattcgagg taatgatggt tcttagaaac ttagtgccaa
    23881 taataatatt tgcagtagtt atagcacttg gattattaaa attcgaaaat gctatgataa
    23941 aaggattcac atactttgga aaaggtgtag taatagttat aactttagga cttgctgctg
    24001 ccatagttga agctttaaca ggaatagttg taatacctgg aatgaaacca atcagtgaag
    24061 gtatagaaat agttggagat atagcaatag ttttagcagg agcattccca ttagtgtttg
    24121 ttataacaaa ggtatttaat aaaccattaa tggctttagg aaaagttctt ggaatgaatg
    24181 atgtatcagc agcaggcctt gttgcaagtt tagctaactg tataccaatg tttggtatga
    24241 tgaaagatat ggacaataga ggaaaaataa taaatgtagc attctctgta tcagcagcat
    24301 tcgtatttgg agaccactta ggatttacgg caggatttaa ttctaatatg ataacaccaa
    24361 tgatagttgc taaattagtt ggtggtataa cagcagtatt gttagctatg gttatcgcaa
    24421 ataagacact aaagaaggag aatgtataag atggatatat caaatataga taaaaattta
    24481 attgaaacat tagtaagaca aataatagaa gaaaaaataa gtggaactaa agacacagta
    24541 gattttgtta gaaataaaga cattagtgga ataacttcta taaagttacc aactgtaaaa
    24601 gttagtgaat ctgatagatt agatacaggg aatccaagtg atgtagttta cacaaaagat
    24661 ttatttacat tagaggaaag cccaagatta ggttgtggta tgatggaaat gaaagaaaca
    24721 acttttgatt ggactctaaa ctatgatgaa atagattatg taatagatgg aactttagat
    24781 ataataatag atggaagaaa ggtttctgct tcttcaggtg aattaatatt tataccaaaa
    24841 ggaagtaaga tacaattttc tgtacctgat tatgctagat ttatatatgt aacatatccg
    24901 gcagattggg catctcaaaa ttaataaaaa tcaagttaag ttaataataa tcaaataaat
    24961 aatttaaaat acaaactctt aaataagcac acatatttaa aaaagctatg aattaaaatt
    25021 catagctttt tttataaaga atgttatatt ttagacgtat tttttctata tttactggga
    25081 gacatattat attttttatt aaataatcta ataaaatgct ctacatttgg ataaccaata
    25141 ctattttact gataatcttt tccttatcac taatcttaca ttttaaaata ttatttttac
    25201 tcgtaatatt atcataagaa tttgtttctt atttaaaact aattagaatt ataaagttta
    25261 ttgccatgtt attaataaaa taaatccagt taaatcgagt gctagttaaa gtaataagaa
    25321 acttttacaa tggtttcctt tatcgattga aataaaagtt aatatggtat aatatctaaa
    25381 gagagaatct tatcaattag aatatgcata gaaacaagtg gcttaaaagg agacgttata
    25441 tggaagagat agtaaagaag gaacaagcaa gtatgaatga tatttttttg tatcttaaag
    25501 ctaaatcaaa ctcattatat aaatttgtaa tattatataa tgagtttatc aataaaccta
    25561 aagattatgg aactggggaa cttataaaca tggttgaagt acatatgcta acagcgattg
    25621 aagaaaatcc aggaataagt ccaactcagt tagctaaaat atggaacaga actaaaggtg
    25681 caatatctca aactatatct aaattggaga aaaagggtta tataactaaa gaaaagaaag
    25741 aaggaaatgc aaaaactata ttactatatc caaccacatc aggagtagag ttaagtaagg
    25801 cacataaact atatgacacc atagatgtta caagaacatt tgaatactta atcaaggagt
    25861 gtacattaga ggagatagat agtttttata aagtaattga tttgtttatt aatttattag
    25921 aagaatctcc gcaggaaaat aatgattctg aaaaagtgta gctgagattg aagttgaata
    25981 aagagaaata gatattatag aagtagtact taagtacaca ttatataaaa atataatagg
    26041 tataggatta aaaagtttag tggtttaaag tttaaccact aaactttttt aatgtctata
    26101 atctactatt atttaattta ctaaaaataa aaaaactcat tatattaaga taaaaataga
    26161 aaaataacta gaaaaatact ataatatatc agcttaatac agaaaaaagt taaaaaattt
    26221 gagaaaaata aaaatgaaaa cgttttatat tgacatagag aaaaagtagt gataccattt
    26281 aaatatagtt tagtagctaa actatattta aattataata actattttag ggggatgtta
    26341 tgaatttaaa acaattaagt gaaaaatacg aagaatatgt aattcaaatg agaagagaat
    26401 ttcataagta tccagaatta tcttttaaag aaataagaac aacccaaaga ataagggaag
    26461 aattacaaaa aataggggtc ccttttgtat ctattgaacc aaatatcgta atagctacta
    26521 tacaaggcaa aaatgaaggt aagacaattg caattagagg agatatagat gcgcttccaa
    26581 tgcaagaaga ttcagatgtt gaatacaaat cagaatatga tggaataatg cattcttgtg
    26641 gacatgatgc tcatggagct atgttactag gacttgcaca tatgctaaat gatataagaa
    26701 aagatttaaa aggtagagta ttattagttt ttcaagcagc tgaagaagtt ggtggtggac
    26761 acaaggagat aatacagtac tttaaggaaa atggaggacc agatagatta atagctactc
    26821 atgtttggtc cgatattgaa gctggtaaaa tttctgttga accaggacct cgtatggctg
    26881 gtgggtctgg ttggagaata gacataacag gtagaggagg tcatggttct agaccagatc
    26941 aaagcataga tcctataaag ccagcttgtg atatagtttt aaaagtatct tctataccag
    27001 ttaatcatat aagtgtacta gaacaatgtg ttgtacatgc atgtgcaata catggaggaa
    27061 ctacaatagg aaatgttatt ccaaacaatg cagaggtaat aggtggatat agatatttta
    27121 ctgaagaatc aggcaaaaaa gtgtttgaca ttataaagca aatgagtaat ggtgttggac
    27181 aagtttatgg agtggatgtg aaggttactc atactggagg cataggacct gttatcaatg
    27241 atgaagaagc agttaagatg gctaaagaaa tagtttctaa tatagatgga ttggagttag
    27301 attcttatga gccaatatgt gcatcagatt gttatggtga aatattaaaa gagtattctg
    27361 gcttttattg ttatctaggg gtaggtaaca aagaaaaagg aataatatat gcacaacacc
    27421 atcctaagta caatatagat gaagatacat taaagttagg ttgcgaattt atggctaaat
    27481 atgcagttga atttttaaat aaaaataata actaaaataa atcgaatttt ataaatgggg
    27541 gggatgaaaa tgcaaggtgc attaaaggaa aataagaaaa aaagtggtgg aggattttta
    27601 ggatggattg aaaaagttgg gaataaaatg ccacatcctc tagcattatt tacatatatt
    27661 acattgatag tagtagcatt atctgcaata gcaagctttt taggtttttc agcaacaagt
    27721 cctgctacag gaaagttaat aaaagttatg aacttaataa gtgcaaaagg tttagtacta
    27781 tttatgcaag agtttgttaa gaacttccaa aacttccctg tgcttggagt agttttagtt
    27841 atggcagttg ccacaggagt ttgtgaaaag acaggatttt tttcaactgc cataaaaatg
    27901 agtttatcaa aagttaaggg gaatgcggtt gtatttataa tagcttttat aggagtattt
    27961 gctaatcaag ctggtgatgc tgcttttgta ttagtaccaa ctcttgcagg agcaatattt
    28021 tatggattaa atagaaatcc attagctggt atattctgtg gatttgcatc agttggtggt
    28081 ggatttgcaa cagctgtaat tcctggggga tgggacgtta cgctaacgcc aataactgta
    28141 tcagctgctc aaactattca acctgcattt gatatgacat tattagctag ttattatgca
    28201 ctatttgtat ctgcgtttat agtagctaca gtatcaacaa tagtaacggt taaatttata
    28261 gaacctaaat taggtaagta tactggtaaa ccagaaggta tagatgataa tcaaggtttt
    28321 gaggtcacaa aagaacaagc aaaagcagca aagttagcag gttttacagt tttagcttat
    28381 gtagcgttat taattgcttt gtgtatacca gctaatagtt ttttaagaag tccagaaggt
    28441 tctttaatat ttggagcacc acttatgtct tgcttacagt tttttatagt aatactattc
    28501 ttcttgccag ggattgtgta tggaatgagg gttggtaaaa tcaagactgt aaaagactta
    28561 aatgatatat tatgtcaatc aatggcagca atggcaccgt ttatcgtact tgcaatagtt
    28621 ataggtcaat tcttaacgct attctcagtg tctaatttag cacaggtact agctataaaa
    28681 ggtggagcat tactcaactc attgccacta ccaccacaag ctataatact gctattctta
    28741 gtactagtag cgtttataaa tatatttgtt ataagcggaa gtacaaaatg gatgatattt
    28801 ggaccagtat ttgttccaat gttaatgcaa ttaaacatac atccagcatt tactcagttt
    28861 gtatatagat taggagattc tgtaaccaat catttatcac cattaaatgc attctttata
    28921 atacttttag caacagtcca aaaatacgat aaaaatgcag gtatgggaac tatattctca
    28981 gctatgatac cttacactat aggttacttt gtagtacttg cagttttagt agtagtttgg
    29041 atgacaatag gtataccagt aggaataggt ggacaagttt ggttataaaa catatttaat
    29101 aattttggga ggaaagaaaa tggaaacaac tgaaataaga tacaattttg atgaagtaat
    29161 agatagaagt ggaacaaact gtcttaaata tgatcttaag agtcaattta tgccagaatc
    29221 tccagaagat gcactaccac tatgggtagc agatatggat tttgcatgtg cccctgagat
    29281 aattaatgca atgcatgaaa gaatagacag aaaaatattt ggatatagct ctcaacaaac
    29341 tgatgattat tatgaagctg tatgtggatg gtttaagaga agatttgatt ggaaaataga
    29401 aaaagagaat atattcttta gcccaggggt tgtgcctgcg ttaggatttt tcacacaaat
    29461 attaacacaa aagggtgatg gtatcataat agaaaagcct gtatactatc cttttgaaga
    29521 taaaataact aataatgaaa gaaaagtagt taatagtcct ttaaagtttg aagatggtca
    29581 ttattctatg gattatgatg gatttgaaga attagctaaa gatgaaaata ataaggtgtt
    29641 tatattatgt agtcctcata atccagttgg tagagtatgg aaaaaagaag agcttagaaa
    29701 aatagtagac atatgtaaga aatatgattt gtggataata tctgatgaaa tacattgtga
    29761 tattattcgt aaaggtgaaa agcatatacc attagaagta gcatgtcctg attataaaga
    29821 tagaataata acttgtacag ctccaagtaa gagttttaac ttagctggta tgcaattatc
    29881 aaatatagta atcaataata aggaattaca aaaaaaatgg atgcttgaaa cagattctaa
    29941 attagctata ttcctaccta atccattcgc aatagttgct actaaagttg cttataatga
    30001 ttgtgaagat tggatgaatc aagtaaatga gtatatagat ggtaatatta aatatgtaga
    30061 agattttgtt aatgagtata tgcctaaagt aaagataata aaatctcaag gaacttactt
    30121 agtttggtta gactttagag ggtatggatt agatgcaaaa cagcttgaat atgtaatgct
    30181 taacaaggcg aaggtattgc tagatgaagg atacatattc ggagaagaag gagcaggatt
    30241 tgaaagaata aatgttgctt cacctagaac aattatagaa gagtgtatga atagaataaa
    30301 atgtgcattt gaaggattat aatagtaata tctaaataat atatttgtgt attttaaaaa
    30361 aagactatgc taaaaaaata tttcaaagca tagtctttta aagttttatg atgagtttaa
    30421 aaaatttcaa aacgttacta ttcacttata tgtttatatt agaaataatt ccacaatata
    30481 ctcattttct aaagttgcac ttttatacac cttgcttcac caatatcatg tgtaaccaaa
    30541 atagtagact tattctcatt cttaataata ctataaacat catcacaaac taataatcta
    30601 gtctgataat caagagctga aaaaggttca tctaaaagta gaatatctgg atttacagaa
    30661 agtgttctaa taagcgcaac tctttgtctc atacctccag ataattcttt tggatacata
    30721 cttctaaaat cccataatcc ataagtcttt aaaaggcttt caactctatc taaagatttt
    30781 ttatcttttt tgccttgaat ttccaatcca atagttatat tatccattat atttctccat
    30841 tcaagcaaat tatctttttg aaacatatat ccaatatttc cagtaatctt tatatcacca
    30901 ctagtcggtt ttaaaagatt agtaagaata tttaatattg tagatttacc acttccagaa
    30961 ggaccaagca aagttaatat ttctccttct ttcaagttaa aattgacatc ctttaatact
    31021 tcaagctcgc cttccttagt gtagaagttc atatttatat ttttaacttc tactatgttg
    31081 tcattcatta tgccaccccc tataactttt agctcgtata tattatgtta ttaacaatat
    31141 gacctatttg taccattttt cataaatata atataaatat tttgtttatt tacgtatttt
    31201 cttagtaact tgtacgtata aattatagat aaataaatta taaggtaggg gataaatttg
    31261 agtaacataa taacgaattt aatagagtca atatttacta atccaataac tatattgttt
    31321 ttacttgcaa taactgtgta ttctgttttt aaaataatag aaaataacag agtatattca
    31381 tttgtaagtt caaaattaga cgaaatcaat agagactata agacaagtga gttttataaa
    31441 aaggtaaggg atgactacta tacatatagt aaagaaaatc cttatgcaga cgtaaatata
    31501 acttcattta tagaggaagt tgtatctgat ttaaagcata ataatttgcc attgttagaa
    31561 aaaattagaa gtataaaaaa ttcatcttca ataagtatat tacttggggt tttaggtacg
    31621 tttgttggtc tttctacaat gcttttatgt gttgatacta aagacattat aaattcactt
    31681 ccttcaacta ttagtagtat gcaaactgca tttacaacta gtatatttgg agttgtattt
    31741 tctctaatta taggttactt tactaagata aaagattgtg aacatgtttt gatacaaata
    31801 atgttaaaat ctgaaaattt actaacatct gaaataactc attttaagtc agaaagaatg
    31861 gatttaaaag tagaagaggt aaaaaataca ataaaacaaa taagtaagtc tatagaagct
    31921 attgaaaaat ttgataaaat atctaaagat ttaaatgact ttaatgatga atttatcagt
    31981 ggtatagaag ctttaaaaag ccttttagaa ggttctcaaa gttctattaa gacatttgac
    32041 cagagcgtaa gaaaattaga taaacagttt aatattttaa atataaaatt tgtaaagctt
    32101 tttgataaat atgataatca agataatata aataaagaga ttttatttga tataaaagaa
    32161 tcttcaaaaa atatatacaa tgccactgaa agccaattca aaattagaga ttatataaaa
    32221 aatataaatg caggatttgc tctatatgaa agaagtgctc aagatttatt aactaaatta
    32281 atgacccatg aaaataaaat atctcaaaat caaaaaatcc ttttagatga aaagtttacc
    32341 ttagatgact caataaaaaa tctctcaagt attattgaaa acttttctaa tgacctacaa
    32401 gttaaactgg atatgatgtt tgaaaattct ttagatattc aagataagtt agatgttatg
    32461 tttaataact cttttatgaa tgatgaagtt cctcttgata gtgaagaatt atttaaggat
    32521 gatgttaata atgtatttaa tccttttagt gaagaaattt atgagataga ggataaagaa
    32581 ataaaggtca taggtgagga tgagttaaat gaataataaa tatagaagaa ctgttaacag
    32641 agaatttgaa aagagtagct tttggccaac atttacagat ttattatcta ctgtattgat
    32701 ggttgtgatt cttatcttat ttagctcaga aagtatttca ggttctgttg aacaagattt
    32761 agctaagaat gtcaatgctt ctgttgaaga aacttttaaa aaaagtggaa tacctgtgaa
    32821 ggtagataaa tctaatgggc aagtaacttt tggtgaaaaa accatgtttg atgtagatag
    32881 tgatgtttta aaaccagagg ctaaagaaat gctaaaaatg tttgttccaa agtacataga
    32941 gactatttat aaagattatg gtgactatat atccaaaata gttatagaag gtcatacaga
    33001 tgatgtggga agttatatat acaacttaga tttatcgcaa agaagagcat atagcgttgc
    33061 taaatttata gtgggagatg aaataggtga ctataaatac aaagataaag tgactaagca
    33121 tattattgca ataggaaggt caaaagctga actcatcaaa aatggtgaca atagcgtgaa
    33181 tagagatgca tctagaagag tagaactaaa atacgaaata aatattaatc aaaataaata
    33241 attaaatttt tataaaaaaa aagaaggcag ttggtgtgag ctttaagcct tctttaagga
    33301 aaaagtttat ttatttttgt tgatacttaa catattatag tttttagaag cagtttgcaa
    33361 tatattaaac gtaaatggtc gtttaaaatg cataactgga tactactgat gtaaaatatt
    33421 tcattttata taatataaaa attatacagt gtcaattttc tatattattg tactataatc
    33481 tattatttaa aatattatgt aaaaaaatat cataaaaacg catatcatgt tataattact
    33541 agagtattat gaatatggag gcgtagtttg tgatagaaat aagtataaaa aataaaaaaa
    33601 attctaaaat taaaactttg atacttttat tgatagtatc tatatcgatt tatttaactg
    33661 gttgtactac atcagataat ggaaataatc aatcaaataa taatgattct ttgtctagta
    33721 gtatatcaag tgataagaat gtaaaaattc attttattga cactggaaat agtgatgcaa
    33781 tattgattca agatggtaaa acttttacat tgatagatgg gggagataat gatgatgagg
    33841 gattaatggt agattaccta aacaatcaag gtgtaaaaga tattaaatat cttatagcta
    33901 cccattctca tgcagaccat ttaggtggac ttgattctgt tgtcaaaaac tttaatatag
    33961 aaaatgtttt tgtatcgaat ggttcagcag aaacaaagag ttatagggac tttataaatg
    34021 ctttagcaaa taagggttta tccccaagtg taccgcttga aaataataag ttctatttag
    34081 aagattctta ttttgaagtt ctaaatacaa atgggggaga tactactaat gaacaatctc
    34141 tagtccttgt atatactaat gggaatgata aagttttatt tacaggtgat gctgaagaag
    34201 gtaccgaaaa agaaatacta cctaagcttg agaaagtaga ccttttaaaa gtagctcatc
    34261 atggttctcg tagtagttca tctcaagagt ttttagataa agtaaatcct gaatatgcgg
    34321 ttcttttagt aggcaagggt aattcatatg gtcatccaca tcaggagaca atgaataaat
    34381 taaaaaaaat gggagtaaaa gtgcatagaa gtgatgagtg ttcagatata atatttgaat
    34441 caacaggtga tggagtattt acaagttgta aagatggaag ttataataaa ggcgttagag
    34501 aagatggaaa ctctggaaaa tcaaacagta atacaagtaa aaatgattct tttaaaaata
    34561 aacaaaatac atccaattca gaagaaatag tgtattttac tccaaaaggt aagagctatc
    34621 actctacaaa aaattgtagt gggctttcaa gaagtaaaaa aatattatca ggcacaattg
    34681 cagaaagtaa gaaaaatgac ccatgtgata tatgttatgg aaaataacaa aaaaacaacc
    34741 aatttatcta taaagcttct gaactttaaa tcatttaaaa aataaaataa atgcataaaa
    34801 aaataagcta taatcaatag ataacacatt ttatctatac gaatagctta tttttttaag
    34861 tattttttaa tagctattta ataactctaa atacaccagt tacaatacct acaatttcaa
    34921 cttctgagtc attgagcata attggttcca taaaatcatt ttctggctga agtcttatta
    34981 aatttccttc tttaaaaaac ctcttaaccg tagcagattc accatttata agtgcaacta
    35041 ctatctgaga atttaaggct gtattttttt tgtctactac aacgtaatct tcatctaaaa
    35101 ttcctgcatt aatcatactt tcgcctttta ctcttaatac aaaattgtta ctgcccttta
    35161 ctaaactggc agggaatgga atgtattcct ctatgttttg ttgagctaaa atgggttctc
    35221 cagctgttat ttgacctact aaaggaagct ctattatttc ttgattagct ccagaaacat
    35281 catttacttt actacgttct aaaacttcaa tagctcttgg tttagtaggg tcctttctta
    35341 tgtatcccag tttttcaagt ttatttagat gagagtgcac agttgaagta gatcttaacc
    35401 ctacagcagt acatatttct cttacagcag gtggataacc ttttaatatg atttgagact
    35461 ttataaattc caatatcaag acttgctttt cagttagatc taaatacata acatcactca
    35521 tttccaaaca tattttgttt ttatttccat acactttata tttttaatta taacataatc
    35581 catttatatc tgcaaacatt tgttcctgat ttttaatcgt cctcaatcca ttcaaaattc
    35641 ttgactatat cacgttttac atttttctta tgagctgcat aaagctgagt agttgtgaca
    35701 ttatcatggt caagtaagtt ttgaacatca tatatagaaa atcctgtttg gattagagaa
    35761 gttgcagccg ttgctcttaa tttatgggga ctatatccat tgtctctagt agtatcaagt
    35821 ggaatagatg tatatttttt taccagtgtt cttatagcct ttgctgtaat tctcttattt
    35881 tgaagagaca aaaataaagc atctttttct tcatcattta atagttcatc tcttgttctt
    35941 tcgttttgca aataatcttt tattacatgt tcacaagtat gatttatagg cattaaaact
    36001 tctttcccac gttttctata tattttaaat tcacctcttg aaaaattaaa agaggagata
    36061 ttgagttctc taagctcatt taatctaagc ccgtatgtaa caaataatgc tagtatagct
    36121 ttgtcacgta atttagtttt tctccaatat accttttctt tctctgtaag cccttcacct
    36181 gtttctactg attcaagcat cttagcaact tcatctatct caaggcgctt aatagcatct
    36241 ggctgaggtt taggaagttt tattggattg aatccatcag ttatattatt atctatctga
    36301 gagtttctgt ataagaattt aaatagagta gagatggatg atttttttct tgctaaagct
    36361 ctattgttat tttcaaaaat caatgtgttt ttttctgtat ttttgtaata tctactgcaa
    36421 taatcaccta agaataaatt tatatctctt gattttattg tattaaaatc atcttctgta
    36481 atgtctttta cacaatctgc atttgttaat tctttggttt caatcaaata tgaacaaaaa
    36541 aaattaatat cttctaaata agcaagtcgt gtagaaactg caacagaacc ttttaaatat
    36601 ataaaataat ccttcataaa tacaggaagt ttattttcca aaagtagaca tttttctatg
    36661 agttcatttt ctttgataac aatattatca ggtttatctg atttattatg tacttttata
    36721 attttcttat cattattcaa aattaaacct cctaaaacta aaatataaat cttttatatt
    36781 attttttgat atttatacta agtgagtata aatatttaat ttaatcattt tttacatttt
    36841 taagagatta gcagtgcttt agatgaaatt atcactaact attccctaaa tccacattta
    36901 aagactagtt gaatttaagt actctttttt atttctcaat atatttatat aaatatattg
    36961 agaaattttt tatgctctac tagaatcttt tttatataat atttttatat gtttctaacg
    37021 aaaccaaata ttagtaaaat atgtatttat ttaactaaag tttttaaatg ggctgactaa
    37081 gcttaaaata taggatatta tgagagttac tattgaaaaa ataaacccta ttgccataaa
    37141 gaaacttata aatatgttat acttaactat taaactggat atattcaagt tatcaaatcc
    37201 aaataagtat gtaattgaac ttattacaaa aataactata actataaagc tcaggccatt
    37261 taagctattt tttaaatcag cactactaag tgacatatgt gtagatatag aatacattaa
    37321 aaacataaat ataaaatact tcaatgaata tacactaggt gttaacaaca ttattcttat
    37381 aaaattggaa atatcaccta aaataatgtg tataaaacca tttatattta aattattaat
    37441 catgcttaca tataacttta aatctatatt ttgagtcact ttcatataac tatctggcag
    37501 taatatctta aaaattaaaa taatcattat tgttccacct ataataggtg caattcctat
    37561 aaagaaattt cctatacttt gataaagatt atctttttta tagctatgac ttacatatcc
    37621 tagtatacca tcatttttac tttctattgg tctgaaaaac ttaactgaat ttattttatg
    37681 catgaaaatt aaacacatta tcaaatgact caattcatga acaaatgttc ctatagctcc
    37741 agttacaata attccagttt ttccaaaaga tgaaaatata aatttattat ttagattttc
    37801 tgtaatgcta aaaatcaatc caaatacaat aaatattcct atgaaacaaa aaatatttat
    37861 tacacttatt tttaaaattt cgattatata aatcataagt taaatcctca tgtaaaagta
    37921 tttaactact ctacttcata tccattacag cttaaaattt tacaagcatt ttctatatcc
    37981 ttttctttta ctaagatata gtctgtatca taagtagaaa ttgcaaatat gcttattttg
    38041 ttgtctgcta acaaactact taacttagat aaaattccta caagtgaaaa gtctaaagga
    38101 cctagtatct taagtattct ccactccttt tctgacttaa catcagaagg aatattatta
    38161 tttaaacata caacacttaa ttcatcatca gttctagtta tagagtaaaa cttctctgta
    38221 tctatccatg ttggtatttt actgtcatta tttaatctac atactgcata ctcttctacc
    38281 aataatttta atttcataat gtatatttcc tccaatctta tttgtttact taagattata
    38341 cattaaaagt tacataaaat aaaacatata aagtaaaaaa ggttcactat agtgtcctat
    38401 ttctatagcc aacctttaaa acttaattaa attctaataa agagatatat tatctaggtt
    38461 caattataag tttaatggct gttttcttat caccttcgat ttctatatca gtaaatgcgg
    38521 gaatgcaaac taaatccatt ccactaggtg caacaaaacc tcttgctatt gcaattgatt
    38581 ttatcgcttg atttagagct ccagctccta tagcttgtat ttctgcaacg cctcgttctc
    38641 ttagtactcc agccaaggct ccagctacag aattaggatt agattttgat gaaactttta
    38701 gtacctccat ttcaacatct ccttgttaat ttgttaaagt atccattacc taaagtacta
    38761 aatcataatt gccatttact aattacaatc atcatttaaa gtatactttt ataaaaatat
    38821 acttctataa tcgttttaag aaaaccttta ttttttttaa ccattttatt atgaaaaaac
    38881 tacaaatttc tttatattct ataagcattt tccaatattt ctaaattttt tatatctttg
    38941 agctataatt tcctctttat ccatatcttt gtaatgattt aatctttcta aaatgtaagc
    39001 ttttatttct tttgaaacag cttctacatc tttttgtgct cctccaagag gttcttttat
    39061 aatcttatct attattttta aatcatataa atcattactt gtaagcttca taacatcaca
    39121 agcttcttta gctttagatg aatctttaaa tagaatacta gaaagccctt ctggagaaat
    39181 cacagaataa actgaatgtt ctaacataca tacatcattt cctactccga tacctaaagc
    39241 tcctccacta ccaccttcac caattacaaa agtgattact ggaacagaaa gtttactcat
    39301 ttcaagtaag tttcttgcaa tagcttctcc ttgtcctctt tcttctgctt ctagaccaca
    39361 aaaagctcct gatgtatcaa taaacgttat tataggtcta ttaaattttt cagcttgttt
    39421 cataagtctt aatgcttttc tgtatccttc tggatgaggc attccaaaat ttctttttat
    39481 attttctttt gtatctcttc ctttttggtg tccaactata gtaacattaa actttcctat
    39541 ctgaccaatt cctccaacca tagaagggtc atctttaaaa agcctatctc catgaagttc
    39601 taaaaaatta gaacaaatat gttctatgta ttccaatgtc gtaggtctct ttatatctct
    39661 acttaatgtt accttttcat atgctgatag atgtgaaaaa gcatcttcct taagcttttc
    39721 caatttctca ttaagtgaat ttattttatc acttaaatct atattatttg ccttagaaat
    39781 agttattaat tgtttaatat cattttctaa gacttttatt ttttcactat tattttcaat
    39841 caaaacagtt cctcctttat gccctatttc ttgtgcatag caagaatttg atataatact
    39901 tccttcattt ttcttctatc tactatcatg tcaataaaac ctttttcaag taaaaactca
    39961 gaagtttgaa atccttcagg aagtttttga tttattgttt gctctattac tcttggacct
    40021 gcaaaaccta tcaacgtatt tggctcagaa attataatat caccaagcat agcaaaacta
    40081 gcagttactc ctccagtagt agggtcagtt agaactgata tatatggcaa tgatttttct
    40141 tcaagcttag aaagtgcttg agaagtcttt gccatctgca taagagatac cataccttct
    40201 tgcattctag ctcctcctga agcagaacaa ataattatag gtaaattatt ttcagcagca
    40261 tactctattg aataagttat tttttcccca acaatagaac ccatacttcc catcataaaa
    40321 tcaggattca ttacacaaat aactgtttta attccattta ttcttccata acctgtgaca
    40381 acagcttctg actcttttgt tttttcctta taagagtcta ctttttcttt gtatttagga
    40441 aaatttagtg gattttgaaa ttctacatca gaattaaact ccataaaagt tcctttatca
    40501 atcaataaat ttattctttt tcttgctctt aagccataat gtcttgaaca ttttggacat
    40561 acaaatgaat tttcttctat gtcctttcta aatacatgac tatcacaacc tttgcaatag
    40621 gtccaaaatt tatcatctac actattcttt ttaaagttgt catctaaaga aatcgtaaca
    40681 tacttagatt cttttgatga taaaaatttt tttatcataa tctatttact ccttataatg
    40741 tagcaaattc tttcttcata aagacatctt ctataaattt ggtatgatga gtatcttctc
    40801 taaactcctc acttgttaca agtgcctttt gaaattctac atttgtatta ataccttcta
    40861 caataatttc gtctagagct ctatatattc tacttataca ttcttctcta gtttcagccc
    40921 aacatattaa cttacctatc atagaatcat ataaaggtgg tatagtatat cctgcatata
    40981 caaaagtatc aaatctaaca ccaaaacctc caggtaaatt taatgattct atcttacctg
    41041 gtgatggagc aaaattcttt gatgaatctt ctgcatttat tctacattca atagcatgac
    41101 ctctaaaagt aatatcttct tgtttaaaag gaattttatc cccattagct atagatattt
    41161 gaagttttat aaggtcaaga tttgttacca tctctgtaac tggatgttca acttgtattc
    41221 ttgtattcat ctctataaaa taaaagtttt tatctttgtc aactataaac tcaatagtac
    41281 ctgcaccgat ataacctact ccttttacta tatctactgc aattttatga agtttttgtc
    41341 tttcttcatc tgaaaggtat ggacttaaag attcttctat tactttttga tttcgccttt
    41401 gcatagaaca atctctatca cctaaatgta ttgcatttga atgtttatct ccaaatactt
    41461 gtacttctat atgtctagga ttttctataa acttttccat atataaatca ctattagaaa
    41521 atgctgctag agcttctgaa cttgccatat caaaatttga aaaaagttct tcttcttttc
    41581 taacgattct catacctttt ccaccgcctc cacttgaggc ttttatcata acaggatatc
    41641 caatttctct tgcaacttct aaagcttctt ccttagtttt caaaacagat tctgaaccag
    41701 gaacaacagg gatattcaat tccatcatag tttctcttgc tctagattta tctcccatca
    41761 aaatcatttg ttctcttgtt ggacctataa aaataatatt attatcttca cattgctttg
    41821 caaattcagg attctctgat aaaaatccaa agcctggatg aatagcatca cactttaatt
    41881 taagagcaag atagattata ttttctatat tattataact cttacttata ttatttggtc
    41941 ctatacaaat agattcatca gctatatatc tatgaaaaca atctttatct atttcagaat
    42001 agatagcaac agtttttata cctagttctt tacatgttct gatgattcta actgctatat
    42061 cgcctctatt tgcaactagt atttttttta tcaacttaaa tacctcctac tacaatggtt
    42121 ttatcttaaa taaaggttga ttatattcta ctagttcttc attactaact aatacttcaa
    42181 ttatttcacc tttaatttca cttgttatct cattcataag cttcattgct tctaatatac
    42241 ataaagtgtc gccttcttca actacatcgc caactttaac aaagctatct gcatctggac
    42301 ttggagaatc atagaatgtt cccatcaaag gagctactac tactgataga ttctcattag
    42361 atgtgacagg tgtatcgttt acaactggct tttctaaaga aagatccact actgattctt
    42421 gttgtacact taaaacaggt gaacttgtag attgagcttt tttagatact tctaatctta
    42481 aatcgctact ttcaagtttt acatattcta agttagttga gtctatggcc tttaataatt
    42541 ccttaatttc attgatgttc attttgttac ccccttgtat tattacctgg tgctaatatt
    42601 atatcacaaa aaacaaattt ataaaagaaa aagtgctgac tagagaatca acacatcaat
    42661 atatctttta attttaaatt aacaaccagt aacttatatt tgttttaatt ttccattatt
    42721 aatataaatt ataagtataa aatgaataaa attcaatatt ttttgcaaaa tacaagagaa
    42781 tacaaattaa tacctcggga atttttaaga caaataccaa tattatgcaa tttagacttc
    42841 gctttctttc aaattagtat cattttcttt atttttacat aggatgtact ttaatttagc
    42901 tatcaaaaca ttgctatata ggttaaaagt tattagaatt gcaggaatta taaagtaaac
    42961 tctagcacct ataaaaccaa aaactactgt aataagtatt aatcttttat ttaaagtaaa
    43021 aaaaggtata ttaaaaatac ttttgtcgga tgtttctgga gtataagaat atataactcc
    43081 aaaaatcaaa gtaagcatac aaagtggaag tagtgtataa cttgaaatta ttcccaaaaa
    43141 tcctatactt tcaaaatatt tgctagcact atttgtataa acaaacatgt atccatttaa
    43201 atatgcgcat atacatgata taatgccaaa agttccccct aaggattgag tgtaccaatt
    43261 aaaaaattta gattccatat acctcacctc ctaaaactgt atatataatg atatgcattt
    43321 aaatagtaaa atatatcttt atatgtttct gaataaaatt ttgttaattt cattaattta
    43381 tgtttaagaa atttgaagta tagtgtagta tatattaatg tagatgaagt tttatagtac
    43441 ttatttcata gtgcttaatc aagttatctt attatggatt caaaagttgt ttgtagggtt
    43501 ttatattttg ttgagctgaa aaatttatta taaatgaagg gatgttttcg ctttggtaga
    43561 tacattagaa tttggtctta aaattttatt ttttatatta tcaataattt ggatgggtaa
    43621 aataatgatt ttaagaactg ataagcaaat agtaatcaat cctttgctta ttggtatatc
    43681 tgcaatcctt gtgatgttgc atacctcaca gagtaacatt gaattttttg gattagatgt
    43741 ccaatatata agaatagttt tgtatataat atattcactg ataattttaa taggaatatg
    43801 ggctactaac agaagaaatg gaatttttta gataatctat ttctataaaa tttaaaggtt
    43861 gctagtaaca aatcactaat attagcgttc tgttactaac aacctttatt ttgattatac
    43921 acttaaattg aaaatagaat gattgaataa gttgacagat tattttacat tgacagtaat
    43981 tagaacttct tgagatgtat ttaaatcatt tttgtcgctt agtataactt ttaccactgc
    44041 tttacctgtt ttattacctt taattatcat atcttcacat gaaagtacac tcttatcact
    44101 tacagataca ataaaattta aatcttttgg aaggttatca gtaacttccc agtatttata
    44161 ataactatca attttcttcg taattatttt tctcaaatca atactttcac cttttgctat
    44221 atcaacatta tgatatttag agtccagttt atactgatta tcttttgtat caataaaatt
    44281 taaatcgcaa tttacatcca caccattatg agaaagagaa tttactacat cgtcatcaat
    44341 caaataatta ttggcaagat ttattgaatc catatctttt agacttaaag cttccttagg
    44401 aacctctttt atattattat tccaaaaaat aaaattgtct acattttcaa gatatgatat
    44461 accttttaaa tttgaaatac tctcaccagt tgcataaaat tctccatcta aagcctttat
    44521 attgcttata gtcatctcat ctggatttat atatcttttt acaactgctc ttaaatttgc
    44581 atcaggaaaa atatctttaa gttgattttc gctcaaaacc ttatcatttg aatttattgg
    44641 acttaaagct gctgcagaaa taataaatgg tattaaatta gctaaattca tagtaccctc
    44701 ccacataaat tttttattat aataatttaa tttctatgag agggttctgt ttccttgtta
    44761 tatataccta ctttcgtaca ctttattaat ataaattaaa ataaatttct actattaaac
    44821 ttataaacat attactagtt acgtttttta gcttcacatc taaatattcg cataccttgt
    44881 gacataaatt tgtcttcata ctctgttgta acattatttt catactcact atttcctaaa
    44941 tcaagagaaa tattctttaa tagccaatta tttgcagcaa tttcatttaa actaaactcg
    45001 aataattttt cattatctgt tttaaagtga atttcgccat catcttccaa aaccctattg
    45061 tacatttcta aaaatccaga atgagtgagt cttcttttac tccatctatt tttaggccat
    45121 gggtcacaga aatttatata aattctcgat aattctttag cttcaaagta atccaaaata
    45181 ttgcttacat ctccccataa aaatagtata ttattcaaat tagaagcatc tgctttttca
    45241 acagctttta aaagaacttc ttccttaagt tccatggcaa tataatttat gtcagggttc
    45301 tgcttagcta aagttgttat aaacttacct tttccagtcc caaattcaac atgtattgga
    45361 ttatcatttc taaactttaa attccacttg ccttttaatt tgtctatatc gtctcttaaa
    45421 acatattttg tataacttaa aagcttttca tctgcacctt tttttcgtct tcttctcaca
    45481 ataattctcc ttacatataa aaaattagta aaatacattt ttattataca ttatctcacc
    45541 aaaaaataaa aagaactctc ttaaaataga aatttatttc tataaagaga gttctaaact
    45601 tactaaaaac ttaatcttag tggcaccctg aacaaccaga gcatcctcct ccaccttgat
    45661 ctttcatatt ttcaggaata actctaaatc caaatcctgt atcttctatt attatatctc
    45721 catactgact atattcatca gagctcatta caaattgtaa ttctccaact tcataagtta
    45781 agtcatcttc ttttttctca tctaaagcta atccaaaaga aggacctcca caaccaacac
    45841 ctgcaaagta tactcttata ttattaggtt tatcttgatt gtcttttaag atacttttta
    45901 aagtatcaat agctgtttct ggtaaagtaa ttttcatcaa atcattccct ttcaaatatt
    45961 ttattaaaac aatatctatt atatacccat acaaggtaca taatcaatta gtttttgcat
    46021 attttactaa aacttctacc taatattacc taaggcttta aaatatttta tataatattt
    46081 tattacctta aataaatacc ctatcataaa cttagtaaac aaataaaatt attattctaa
    46141 aaaatataat aattttattt gttgttttaa tattataaca catttgataa tgtccaattc
    46201 atatatgcaa aatttatata ctttaaaata tctaagaaat tattcaataa aaaaatacta
    46261 ttttttaaaa attatcatta ttgataaagc tctactattt atatttttta gtgtattcat
    46321 gtataataag taaaagcaca acggtatata ctgttgtgct tttttgtaat taataaacaa
    46381 tattttggtc tataacaatg aaaaatggct actttccata attgatttca tctgacataa
    46441 gcaaaaaggg tgtccagctg ggtcaatcat aactctccag tcatcagtaa attgctcctc
    46501 tgcgattgta gctccacaat gaattgcata ttgaactgct tcttctaaat ccttaacagc
    46561 gaaatccata tgagccattt gctgttgaga ttcaggtttt tctggttcta ttatgcccca
    46621 agcctttgtt ttttgcaata taaagaaaaa attatatatt ttaatatttt atacttgttg
    46681 aaattgtgta ataaattcaa ctggatacat agtgcgtttt gaaatttctt ctaaagctaa
    46741 accttgtttt aaaagcctct ttatgacgct ttccatactt tctgaaattt ctataatatt
    46801 tttatcaaaa tcataaaacc taaaagttct ttgaccccat gggtattctt ttatataatg
    46861 caaaaattca atatttccta ttctatttat cttactttcc cattgtttga tgtcattaac
    46921 ctcaaaatac aactgaaagt tatttgattg ttgatatatt ggtaaatcat atccaattat
    46981 agctttataa ttactttgta atccaaatcc attttcaaat gatacatgtt ctcctaaatc
    47041 taatgtgatt ttttgctcca taacatcttc aaaaaacttt tttgatttat ttatgtcttt
    47101 gacaattagc aatactcctc caaatttcat cttatcacta tcctttcttt gttataagta
    47161 ttataactta aaattttgca atttcactgt aaaaatcaga catattagct cggtattttt
    47221 gaggagttat tccacagaca attttaaaat ctttaataaa atgtggtata tcatagaatc
    47281 ctaattcatt acatatagac atccatgaag ttttattatt gtttagaagt tttatagatt
    47341 tattaatacg taccaaacga gaaaatgact tcatactcaa ccctagatac tgattaaaga
    47401 gtctgtttaa atgcctagaa ctataaaata cttttttaga aatttcttgt gaagatatat
    47461 ttccagagtt ttgaataatc aactgaattg ccaaaataaa ctcatatgag tattcaattt
    47521 taatattaga aatcaataat tcttccaact ttaaaatcaa tttatctata gataaagatt
    47581 cattaaatat ttttttaatt tctaaatcta atgaagtatt aattatagaa aatggaacaa
    47641 ctttatcaat aagttcactt tgctgtatac ctataagcgg gaaaaaacca gcaggttgaa
    47701 attctataat tagtataaca tcacatctat tagcaatatt tcctactgtt tttggtttag
    47761 tagttggacc aaataataga ctatgtaacc ctgtggcatc ataaaaaaac accaaagtta
    47821 cacttccatg aggaataatc gtgtaattat cagaaattat tgtttgattt ggaaacgata
    47881 tagtaaaatt cgatatccaa tttcttaatt gtatacaagg caagagataa acaaaattgt
    47941 cttcacaaac tataagtgac ctatttttat ttataaaatg aatactttct ttttttaaca
    48001 tatattatat cctgtcctat cgtgaatatt tattaaagta agaagaatcc atattatctc
    48061 tatatatcat taactgcttt taataataga gatagtatga atactcatta gatatttaat
    48121 aaacaaataa aattaaaata atcaataaaa aatatagtac ttttatctgt tattttaata
    48181 ttatagcaca tttatagtat ttaacttata tccactttac atatgtctaa tttatataat
    48241 taaaaatgct tatctcaaat acaataatta gtccttatac aattaaacca tctgaaactg
    48301 taatagtacg actactactt ttggctgctt ctggtgagtg agttaccata attatagttt
    48361 gtccattgtc tctgtttatt ttattcagta aatctattat ttctatccct gttttactat
    48421 ctaaatttcc agtaggctca tcagcaaata gaatctctgg ttttccaatt aaagctcgag
    48481 ctatagcaac acgttgttgc tgaccaccag ataactctcg tggtgtatgt ttacgtctat
    48541 cagttaaacc aactatatct aagatttcat ctaattgatt tttataatct tttaaatttt
    48601 taccatctaa taacaaagga agcattatat tttcctccac atttaaattt ggtattaagt
    48661 tataaaattg aaatacgaat cctatatttc tacgacgtat tatgctcatt ttctcatcat
    48721 taaaatgtga tatatcagct ccattcatat acacttttcc gctcgttgga gtatctaaac
    48781 cacctaaaat atataaaaga gtacttttac cagaaccaga ttgacccatg atagaaacaa
    48841 attcaccttt cattacttgt aaagatacct cttttaacac tcgagttgtt gtatttccaa
    48901 ttttatattc tttgataata ttttttgctt ctacagctaa actattatgt gtaattttca
    48961 tattaacctc cataattatt caaacttaat ttcttctatc agtttcattt tcttcccttt
    49021 tataataggc actatcgaac ctattaaagt tactataatt cccaataacc caacaataat
    49081 aaatgtttta aaatctaaat ctggtttcat tgaaattttt ggtcctgcaa ctataaagat
    49141 agtttgaatc tcaagtatag atatcacaat accaataaca gctccaagta aacctgaagt
    49201 aaccccttca atcaatgtta cttttatatt ttgtttatta cttagtccta tagatttata
    49261 catagctata gaacgtcttt tttgaatata attaatcagt agattattaa taatacctac
    49321 tgtagcaaga agaaaaatga aataggtcat cttattcata ggagacaaaa aactacttat
    49381 agtatttaaa gaatcattat taaattcttc aactgtacga ctccaattat atgtatctcc
    49441 aaataaatat cttatctgaa tcataacagc atctggattg actgctgtat atactaaaaa
    49501 accataatta gttttatcaa aatcattaac tgcataatgt gatggtataa cagcttctac
    49561 atcatttgca cgggatttaa aactacctac tattttataa gaaaaatcat acttatcatt
    49621 agatagagtt attgtatctc ctatagataa gcctactttt tttagagtat cttcattcaa
    49681 aataacagaa cgtttatcat taaaagcttc tattacttgt ttttttatct caaaatttgt
    49741 ataattgatt ccaaacatag agttatatag ttttatatta tctgtaccct ctagtcttga
    49801 taatgttaca ccattaccag aaatctcatt attcataaca taaagaggta atattttttt
    49861 aattccttcc atatgtctaa catcttcaat aaactcttca ttcatatttc catctgcaaa
    49921 accttgtaat tctgcgtcac gaaacacatc tgttatataa gttttgacaa agttaccaac
    49981 aacacttatt gcaataactg cagaaatact tataaatagt aaagtgatat tctgtattat
    50041 atttttgtta tttttcatat ttctagcagc taatttaccc tcattcccta aaatattttt
    50101 ataaacaaac tcaaaaacta tagacatgat atcagtaata agaggaatca acacaatagt
    50161 agctacaatt aatcctagta atgaaaatcc accagctaga tacaatgtat tttcagggga
    50221 tattcttgga agtaaaatag ataaaataaa cattatactt cctataaaaa gtatagaacg
    50281 atttgaaaca ttcttttctt ctactgttcc tagtacaata ttttttatcg gcaaatggct
    50341 agctttttta acaggtatat atgcactaaa tgaagaaacg attattgcta ctataacaga
    50401 tataatcact ccaatgggtg atattactac tggaattgat attccttgtt cgagagaatt
    50461 tcctaaccca tgaagcatta aatttaaaac aactacacca ataggaatag caattaatcc
    50521 tcctatactt ccgtataata tactttcaag catcaatata cgagttacag ttttttcatt
    50581 ggcaccaata cttctaaatg ttccaataaa aggaagacgt tctaatgtaa taaccttata
    50641 actgctgtat attataaata tactaagggt taatgcaaaa aaacttatta aaaagaaagg
    50701 cattgtcttt tgtctagcat ctgaaattat cttagtttca tttatagtat ttgataccat
    50761 atatttttca gtagaaagtt cttcggataa tttatttact agattttctg taatttcttc
    50821 ttctgactct ataagaactc ttgtatatcc actgccttta tttataattt ttgatagagt
    50881 ctctttgggt agcagtgcat ttacacctct tgtgttcctc aaaaatactg tatcataaga
    50941 tgcaatatca ctaacttgaa aagtataaga ctttccataa atctgcaaag taatagaatc
    51001 accttttttt attttatatt ttgatgtaaa gcgatttgga agaataattt tatcaccaga
    51061 aaaatcagta atactatcgc cattttctaa tcgtggcttg ttgattttat ttagttgact
    51121 taagtctgct gatataagac taaattcttc atagtatccc cctttattat aaatagcaga
    51181 gctttccaat acaccaacct ttgattttat agtatttaaa tcaggtatgt cttctaaatt
    51241 ggttaatata tctggatttt tactttggac agatatagtc gctgtaccat acataccttt
    51301 tgccattttt ctttgtgcac tttcataaga taatccaatt gagaatgaaa caaaaagtaa
    51361 aactgttgat aaaactatgg acaataacat aactgctgtt ctaatttttc gttctttaat
    51421 atttgtgaaa atatacttta atataatttt caaacttaca ccttcttccc ttatctaaga
    51481 tatttcaatc taatattttt atactttaat ctaaattaaa tctctaatag actcctccat
    51541 acttttatca ttctatttat aatattttta atcaaatcac cccttaaata aaaaagattg
    51601 ataaactact atataaatat aataatctat caaccttaat atatttttta tttaacctta
    51661 attaacctta attaaatagg aaaggtgata taaaatgagc tacctaatcc aggtatactt
    51721 tcaacagata tattccctcc atgaacttca ataatttgct tcgttattgc tagtcctaaa
    51781 ccagttcctt ctattttttg ttttgtattg cttcctctat aataacgatt aaacaaattt
    51841 gatgcttctt ctcttgacat cccttttcca ttatcagata taatgatttc aattctttca
    51901 tttaatgtta catgtacaca aactttagta tttttatctc catatgtaaa agcattgaca
    51961 ataagattac taaaagctcg ttttaatagt gtacaatcaa aatcaaagtt aatattatct
    52021 atattactct taaattcaac tatatttgat tcatattctg gataatttaa aatatcaatg
    52081 gataattctt tcaagaatct tactaaatca taattatttt tatttaaagg gattattcca
    52141 ttttttaatt gataggttaa ttttaaatcg tttataagtg tatttgtata ttctatgttc
    52201 tttaacatga ttgaagcata tttatatact ttttcaggtg aataattagt actactatct
    52261 gtaagaagct ctgcataccc ttttattggt gaaagtggag tttttaaatc atgagttata
    52321 tttgaaatcc actcttctct cataatatca gttttatttt gtatctcatc acttttatga
    52381 atttcttcat ttaaaatatt taaactatta tatatatcag caaaaacacc tttaatatta
    52441 actggaagat agcttcgttt tgaaatatca ctaacagcag atgtaatatt tgatatgcac
    52501 tttgttaccc agtaaccata agcaattcca gaaaccaaaa ttattaaaaa tataatccct
    52561 atgattgaaa atacaattga cttaccacct ataaatttac ctccatcaaa aaacatattc
    52621 actttagata tatttaatgg aaaatatata atataaatat agtcattttt attattttta
    52681 attgtattaa agtatacagt tccattactt gaattatttt ggttagctaa tgctaataat
    52741 tcagaattag aataataatc tttatgctct tttggttcta aaaacccata aactctattt
    52801 ccactagaat ctaaaatttg caaccacaat tgattttctc gaagtttttc taatccagac
    52861 tgttttactt gtggcttatt atctataaat acgatttgtt cattaaagtt ttctgtaaat
    52921 tttttcggcc agtcactacg aataaattcc ccatttggtt tctgaatagt aataagtgat
    52981 aagaaaatac ctattactgt caggattaag caaataaaaa tcatgaaaaa aataatgtat
    53041 gaatgaaata ctgttttata actaggttta tgcatttaat caactctttt cttaaacttt
    53101 tattttagtt tgattgttgc ttatataaaa tagacaataa ttattgatat gtaaaaattt
    53161 atttaaaaat acaactatct acataaatta tatttatata attacatgtt atcaagctgt
    53221 ctgttgtatt taataaatca ttttgataac atataaaagt aagataaatt tttccattaa
    53281 ataccttata attatacaca aaatctctat atacgttaaa caatatagag aaaattttca
    53341 tagaaccatc tttatagggg atactttata aaagaataaa aaaattataa tatataaaaa
    53401 acttcatagg agtgtaacaa catcagtaaa gatatgaaaa cactatataa aaattcaaaa
    53461 atattaagaa taatgaaata cttgaaattg cttatatcaa gaaattttat ataatataaa
    53521 ctggtcaaat atgttataat attaaattgt gacaagttca tggaggtgtt tatatgaaaa
    53581 aacaaaagtc gccaatttta cttgaaatgc ttggactatt ttttggttgt atatcaatga
    53641 gtattggtat aaatatgttt ttaaaaccac atacaattgc tcctggagga cttagtggtc
    53701 tatcattagt actaaacaag gttacaggac ttccagtatc agctatcatg ttaattatag
    53761 gtgtcccatt agtaatactt gcttttagaa ttatgggtac aaaaaattca ttaaaaactt
    53821 tatttggaac agttgtattt tcagctatag ttcaattaac agacccatta tcaaaactaa
    53881 gatttactaa tgacttatta ttgtcttcta ttgcaggagg aatcctagtt ggtataggtt
    53941 taggaataat gtttaaatca gatgcttcta ctggaggaac agacttaatt gcactcatac
    54001 ttagtaagaa attcccagga ataaaagcta caaaattcat gtcatgccta gatggaatgg
    54061 ttgttatatc ttctggtata gtaaatcgta gtttagaaac tgctctttac tctggtatag
    54121 cactttgtgt attaataaaa atagcagata tgataatgga aggatttgac cattcaaaag
    54181 cattttttat tatctctgat gagcctgaaa gtttaagaca agctataact gaagaacttg
    54241 atagaggtct tactattctt gatggtaaag gtggatacac tagagaaaat aaagaagttc
    54301 tattagtcgt agtttctaaa aaacaagaac tttatctaaa gagattagtt aaaagaactg
    54361 accctactgc atttgttatt gttacagatg tacatgaggt tcttggagaa ggatttaaaa
    54421 atttagagaa ctaataaaaa ttaatatttt aagtatatat actattttaa ttaaaatacg
    54481 atttattcaa aaagagtgtc tcataaactt tttagttcat gagacactct tttttgtata
    54541 aaatcaaatg cattttcagt attttaacaa taaaaacagg attatctata ttttgaggca
    54601 accactttat tgaaatttta tttagaaaac aatcattact aaataaccag catagatatt
    54661 aaatgattat atctattgtt ttttcaattc atattgataa caaggaacat tttttacagt
    54721 atttccagta tgaatttttt tgatatactt tcctgtacat ttaaatccta ataaatctaa
    54781 tgattttgta gaattttggt tttcttcata ggttattgca attattttat ttaagtttag
    54841 ttccctaaat ccatactgta ttactctttt tgttatctca gtagcaaaat catgtcccca
    54901 atagcttgga tttatacata tacctatttc tgcttctaat gctttaggat ttatattatt
    54961 aaaccccata ttcccaataa ctttattgtc tcttttatat actatagcaa agtggccaat
    55021 tttccctttt ttatatggat ttagaaaaaa tgattttata aactttcttg tatcttctaa
    55081 agatttatgc tcactaaatg gtaaatgttt tactactatt ttatttttat aacagtcaaa
    55141 aaaatcttca acatcatcta atgatgcagg tcttagtata caacttctag tttctaaggt
    55201 tttcatttga ggatattcag aatcagacat ttctaatccc cctttataca ttaatctaaa
    55261 tatactgttc atatttaaaa tacgatatta attatataaa tgttctcaaa ttaaccttat
    55321 ttttattttt aataaaaact aattactata tgaatctttc aaatttacga atttatctct
    55381 atttttatat taaattactt gtgaaatatg tattctaaat tatatattat tagatatcat
    55441 gcttaaaaat tctttggttg ctaaggataa agatatatct tttaaatggc aataacctat
    55501 atttctctta ggtattggct cttttatatc taatttaaac aatttctcat tttccaaata
    55561 atctatgcta aattcttcta taacacaaga cactccaaga tttatatacg caaattctaa
    55621 aagtaattca tgagaaccca attctatatc tgggtttagt tttatacctt ttgataaaaa
    55681 atattcattt acataaagtc ttgaatttgc tttattttct agcattatta aaggcaatgt
    55741 gtttaattct tccaatgata ttttcctacc tttgtattct atgtaatcat ttgcacatac
    55801 aaatatatca tgtatttcaa tacactcaac aatatttagt gtatcatctt ctattggcat
    55861 gtttataatt gctatatcta tattcccatc tttgagtaaa gatataagtt ctctactcgt
    55921 tctatttatt gtagatacat gtatatgtgg atacttctta tgaaaaattt ctaaatattt
    55981 taacaagaaa aaacgtgcag ctgtatctcc tactcctatt ttcagagaac cgtattctaa
    56041 ttttttaaat ttatttattc tatcttctcc tgatgatatt aactttaatg cagtagtgac
    56101 atgttcactt agaattttcc cctctggagt taattttact cctttattgt ttctataaaa
    56161 taataaagta tctaattgtt cttctaattg ctttattgac tggcttacag ctggctgtga
    56221 cataaacaat tccttagcag caagagaaaa actcttatta tttacaactg cattaaaaac
    56281 cttataaagt tcaagtttta tattcatata taattactcc ttatgtcaaa tattagtatt
    56341 atttatttta cttataatta tatttgaatt ataatataca tggtactaat atgacaatat
    56401 taattcttta ggaggatttt agataatgga tagattagtt ggaactgttt caagaggggt
    56461 tagagcacct attataagac aaggagatga cttagttaaa atagttgttg attctgtttt
    56521 aaatgcgtca aaaagtgaaa actttgaagt tagggacaaa gatgtaattg ccgttacaga
    56581 agctgttgta gctagagcac agggaaatta tgctcacgtt gacaatattg caaaagatgt
    56641 aaaagataaa tttggagatg atactgttgg agttatattc ccaattttaa gtagaaatcg
    56701 ttttgctata tgtttaaaag gaattgcaaa aggatgtaga aaagtcgtat taatgttaag
    56761 ctacccttct gatgaagttg gaaatcactt aataagtatt gatgaacttg atgataaggg
    56821 aataaatcct tggtcagatg ttttaacaga agaaaaatac agagaactat ttggatataa
    56881 caagcataca tttactggtg tagattatgt tgattattat aagaatttaa tcaaggattg
    56941 tggtgcagag gtagaaatag tatttgcaaa caatccaaaa actattctta actatacaac
    57001 aagtatttta acttgtgata tacatacaag acaaagaaca aagagaattt taagacaaaa
    57061 tggagctaaa aaagtatatt cacttgatga tataatgaca gcaagtgtag atggtagtgg
    57121 ttacaatgac cagtatggac ttttaggttc aaacaaagct acagaagaaa cagtaaaatt
    57181 attccctata aattgtgatg aagttgtaaa caaaatccaa ggtaatataa aagaaataac
    57241 agggaaagat gtagaagtaa tggtttatgg agatggagct tttaaagacc ctgtaggtaa
    57301 aatatgggaa ttagctgacc cagtagtatc tcctgcttat acaaaagggc tagagggaac
    57361 tccaaacgaa gtaaaattaa aatacttagc agataatgat tttgctgact tatctggtga
    57421 tgagttaaaa gaagcaattt caaaatacat agttgaaaaa gataataaat ctgatgattt
    57481 aacaggaaac atggtttctc aaggtactac tccaagaaga ttaacagacc ttataggttc
    57541 tttagcagat ttaacatctg gaagtggaga taagggtact cctattattt acatacaagg
    57601 atatttcgat aactatacaa aatagtatgt tttaataaga tttaattttt ttggattata
    57661 tatattaaca tgaaaattta ttaaaacctc ttaatagata tgacttttca agagttatat
    57721 ctattaagag gtttatttaa tgttcacaga taagatatat ttaaataatt taaacaagat
    57781 tgtcagaaag ttatataatc ttaaaaattt atataactct aattcttatt tatttctgaa
    57841 ataatatcac tcttcaaaat ttgtcttact ggaataatta cagcaactat actaatagtg
    57901 atatttaaaa taatcatacc tatgtataga ggtgtattta ttttaagaat tggatttata
    57961 tataaatata cacgttttac cataaaataa atcataaatt gtccaataac acttccaatt
    58021 accattataa tacttgcata gaatccatat aaaaaacctt ctcttatcat cataagtaaa
    58081 aacttattat ccgtaatacc catagctctt aaaattccaa actcatgtct tcttgaaaaa
    58141 attaagtagc ttactgtatt gattatatgg aacaaactta ttgcaagaag tacaaataca
    58201 ataccatata taaataagag tttttgattt aagtaggtat tatttttttc aatagcaatg
    58261 gtataatctg ttacgataca tctttttaca tcacttacaa cactttttat gttctcagac
    58321 aattcctcac tgttactatc ttctgtcttt tttatactta ctgaattata attttcgata
    58381 tcaaagttat ttttcatttg cccattcgtc ataactatat ccataccata atcaccaatg
    58441 aaatatatgt tatttgccat cacacgtttt acagtagcag caactacaaa ttcttttgtt
    58501 gtataatcat tcttattttc ttctttaaat ttaacaattt catctgttgg tttcattgtc
    58561 tttggcactt taacttttat tgtatctcct ggatttatat caactgcatc atacatccca
    58621 gttccatcca taggtagtct aactataacc ttattatttt taaccatatc atgggtatta
    58681 atctccccat ctataatata agaatttaat ccttctaaca taccattgtt ataaccataa
    58741 atatttgttt ttaaaagata gccaccttca ttttgctttg tacaaatacc atcaaaaaaa
    58801 gtctttatcc tgtaatcttt ttcaagaggt ttaaagaaat ttttccaaaa tagttgttct
    58861 tctttaattt gcatagctcc aaataaatat cttactggat agacttttga tattccctca
    58921 acattgttta atcttgaaat tttatctttt ggtataccta catcaaaatc tgttgtttgc
    58981 atagttattt ggtagtcaga atttaaacca tcatcagctt tcattgtaag ttcattatta
    59041 tttttagtaa gctgtataga gtaactagaa cataaaaata taattccacc aagtgataat
    59101 gaaaacaaaa ttccaataaa cattcccttt ttttgagtca tgtatttatg agataatact
    59161 tttgtcatgt tagagtgttt tacactttct aatattctct ttttcttatt agtaatctta
    59221 aagtttttca tagattctat actagagtat ttattcaact gatgtacaac acgtacagca
    59281 attaaaatta acaacaataa gataaataaa aagcctaaat aaatagattt ttcacttata
    59341 aaaaatgctc ctggaacaat atcactactc aaaaatatat gtggaaattg ttcatatatt
    59401 gtagacgcca cttcaatacc taagaagcaa cctataggaa atccaacaat aaaaagtaaa
    59461 aataactcta aaaatagtag aaataaaagt tgtttattat tagcgcctaa tacttctaaa
    59521 accccatatt gtgatattct ctgaagtatt gaaacatgga aaatactata tactgctgct
    59581 gcaccaaaca ctccaacaag taatataatt gcatttgtat ttagttctaa attttttaag
    59641 aactcaaata tattatattt ttctatattt tttggtggtt ttactccaaa ttcaactgaa
    59701 agaggccagt ttatataagt tttttctttt gatatgttga attttttcat aaatttataa
    59761 ttttgctttt taatattttt attttcatca tattttacat aaactatata agaatccttt
    59821 tctttaggct gaaaataatc gtttacaaat ccctccagag cagtttctgg gtttgaaaga
    59881 cttgataaaa taccacataa cttatagatt ttaccatcta aattgatttc tgttccaatt
    59941 tctttgttta catttaaatt gtttagagaa tatgtgtcaa gtactatctc tccatcttta
    60001 ctaggaagag ttccttttaa taattttcta cctgtcatgt ctaaatatga agaatcagca
    60061 tttaaaaatt ctataataaa aggttcatct atctgatttt taggttttgt aacgccaagt
    60121 ctatctacag tgtattcctt tgatttttta ttttttttaa ttttattaag ttgttcctta
    60181 tctactttat agaaataatg ataatctcca ctatcttccc ttatcttttc aattctactt
    60241 ttgtctgcac tatgaactaa agaaccaatt cccgtcaata atgctactga tagtactata
    60301 cttaaaacta tagatataga ttgtttttta taatgcttta tatattgaat tgaaaatttt
    60361 actagagaca tcatagtact tcaccaccag tattcaccac aactccatct tcaatatgga
    60421 taattgagtc gcatacttgt gctatatttt cattgtgtgt taccataagt atcgtttgat
    60481 ggaattttgc actactttct tttaataaac ataccacttc cattgtagtt ttactatcga
    60541 gatttcctgt tggttcatct gctaatataa gcgcaggttt atttgccaaa gctctagcaa
    60601 ttgctaccct ctgttgttga ccaccagata gttcgcttgg aaattttaaa cgcttatccc
    60661 aaattcccaa tgtcttcatc agcatttcaa tatattcatg gtctatatgg tttcctttat
    60721 ctaatgtaac aggaagagct atattatcat aagtgtttaa tacgggcatt aaactgtagt
    60781 tttgaaatat aaatcctata tttcttcttc taaacactgt caaatctttt tttcctattt
    60841 tagatatgtt ctttccttta attattacat cacctgaggt tggattatct aatccaccta
    60901 taatatttaa caatgtgctt tttccagaac cagaagttcc aactatagca gtaaatgtat
    60961 ctcgttcaat ttctatactt actccattta aggcttttac tttagtctca ccttttccat
    61021 agtgttttac taaattattc gtcactaata tactcattta atttctcctt tcaatacaga
    61081 tatatgttct ataaaatatt gtaagtgacg ataattacac tcatcctaca aaattagttt
    61141 aaactcttac aattctgtaa gaagatacta aaacaacatc cacttcctag tttagattct
    61201 actataatgt ttccattttc tttttctaaa attaatcttg taagatatag accaatccct
    61261 gtgccatttt ggttttcaac atttttactt ctgtaaaatc ttttaaaaat atcatttagt
    61321 tctctactat caatacctat tccctcatct ttaatagtaa tcttcgtata tagttccatt
    61381 tttattacag aaatagtaat cgtgctatct gatggtgagt attttattgc attttctaaa
    61441 acatttacaa ttgcttctat ggtccacttt ttattatgaa ctaattttat gtctgaaaat
    61501 ggttcgagat ttatccttat atttttagct tctgctttat taaagatagt actgatactt
    61561 tgaataagag tatctttaat tagtagttct tctacttcaa attctataac tccatcctct
    61621 aatttagtca ttttaaataa ggattgtaac agccagtcaa tcttaaaagt ttcatttttc
    61681 atcttttgta aaaactcctt cttctgtaat gtggaaatat ttatattctc cagaagttca
    61741 caataaatgg ttatatttga aagtggagtt tttaattgat gtgacatatt tgatattaaa
    61801 cctttaatcg cttctttttc tgactttgac tgttctacct ctatttctat catatcctta
    61861 atttttttta cttggtgaga aatttttgac gctcttgtat cctttgtatc tggataagta
    61921 acttctttac cttccaatat ttgatttaac atcaaattta attcatcata tctttttcga
    61981 tttattttag tagatactat aaatataaca actgtacata ttataaaggc taatataaac
    62041 atattattct acctcattcc ataaataacc cattccataa gctgttttta tatattttgg
    62101 attagatggg tcatcctcta cttttactct aagtcttctt atatttacag atacaatatt
    62161 atcatcaaca taattttctt cgctgtccca aatatggtgt aaaatttgtt cctttaataa
    62221 tatttgacct ttattttcaa ttagataact tagaagctta tattctacag agctaagttc
    62281 caaacattct ttatttttat atacttttag taacttttgg tccaatttta ttccattgga
    62341 atatattact ttattattcg atttttttct tattgctact ttgactcttg cctttaatac
    62401 agataaagaa aatggttttg taatgtaatc atcaagccct atttctaatc cttttacttc
    62461 atcaatttct gagtctcttg cagtaagcat tataattggt atatctgact tttcccttat
    62521 tatttgacat acatcaaatc catctccatc tggaagattg cagtctaaga ttataaaatc
    62581 tatattttta ctattaaata tatttaatcc ttcttgtttt gtataagcct taaatacatt
    62641 aaatccatca ttctcaaatg cataaaaaag accttcattt aagtttatat catcttcaat
    62701 aattaataag ttcaatttta ctctccttta gattttttag ataaataatt attttcttgc
    62761 attatcatac taaaaatatt ttaattttat ttatttcact aaaaagattg tatttaaatt
    62821 tgttttcaaa ataaaaacat tataatcaag catatagtta tatatttccc aatttaatta
    62881 cgcttaaatt gaaaatataa ctttattctt atataattaa attatacaac aataaagtta
    62941 tattttttaa atatattttt actaggggga atagaattga aaagggttga tgagagaaat
    63001 actatgtttg caagagcaaa ttacaaaaaa gatagtactg cttataatga ctattataag
    63061 aaaaatcctg acaaaaaaga aattgatgat agtataagaa atagaccaaa tttatgtagt
    63121 gaaggaacaa tgacttacaa tgagttaaac tctccaatgg caagtagtgc attcgatttt
    63181 ttatctgata tcaaatcttt atgcgaagga aaagtttctg atactaaagt agatgtagat
    63241 gcaaagtcaa tgacaaaaaa aattaagggt cttgcaaagc agtatggagc ttctgtagtt
    63301 ggtataacta aattaaaaga ctatcatatt tatacaaata ggggtagaca tgaagaaaat
    63361 tacggtgaag aaattaatct aactcataag tatgcaattg tatttggatg tgagatggat
    63421 aaagaaatga taaatagagc tccaatgata tgtgaagtta tagaaacatc aaagtgctat
    63481 gtggatgcat ctatcgtcgg catgatttta agttactata taagaaattt aggatatgat
    63541 gctagaaatc atatggatgc taattattta gtaatgcctg tttttatagc tcgtgatgct
    63601 ggtttaggag atataggaag aaatgctata cttacaaata aagattatgg ctctagactt
    63661 agattaggtg ttgttactac agatattcct cttttagaag atgaatatgt tgattttgga
    63721 ctagaagatt tttgtaaggt ctgtaaaaaa tgctctttta actgcccttc tcattcgctt
    63781 tctaatgata ttaaaattgg tgatgatgga aaatataatt gggtaattga acatgagaca
    63841 tgctatatta aatggagata tttaggtaca gattgtggta tgtgtatatc tgcttgccca
    63901 tttagccaaa atctcgaaac tataaagaat actacttcat ttaagggtaa taatgagctt
    63961 attcaaaaag ctttagatga gtatacttca aaatttggta aaagaatatt tatacctgga
    64021 aatccatctt ggttgaaata attttattta ataaagaatc tgtactagaa tttatcatag
    64081 gacaggttct ttattaaata tataaatttt taaatacttt ttctcgttta taacaattca
    64141 gcaatgtttt tagtctataa ttgacattat aaaatattaa actaaaagga gtaactgtat
    64201 ggaaaaaata ttagtagtag aagatgattc tatattaaat aaaactctat catataacct
    64261 aattgaagat ggatatataa ttacttcaaa atttacagct aaatctgcac taaagtctat
    64321 ttttgaatgt gaatttgatt taataatttt ggatattaat ttaccagata aaagtgggtt
    64381 tgaattatgt aatgaaataa aggaaaatta caatatacca ataatttttt taactgctaa
    64441 tgatatggaa tgtgatatga ttaaaggcta tgaacttgga gctttggatt atataacaaa
    64501 accatttaat atcaatatat ttaaacaaaa aattaaagct tttttaaatc atcttacaat
    64561 aaaaacaaaa caagattact atagggatgg atatcttgaa attaactttt ctgagttatc
    64621 tgccaatata aatggaaatc aaattatatt tacaccatta gaatatcgta ctttaaaact
    64681 gcttactgaa aatcctaaaa gtattttaac aaggaaagta cttttagaaa aactctggga
    64741 tatagatgct aactttgtag atgaacatac tttaacatct gttataagta ggattagaag
    64801 caaaattgaa aaagacaatc ttaagtatat caaaacggta tatggtatgg gatatatgtg
    64861 gttaggtgaa agaaatgaat tttaaaaaat tttcttttag ttctatttat ttaataattg
    64921 ctgttggtat aatttttaca gctattttat ttagtatctc aatttatcta ataactgatg
    64981 atttaaaact aattgctcta ttattaatat atacaatagt actttgtgga tttatagcat
    65041 taataatatt tttacttcat aaaaaaatag ttatattttg ttctagaata tgtcacactt
    65101 tagatagtat gatgaatagt gaagataata ttgaaattga attagaagaa gaaactattt
    65161 tatcacgtat caatcacaga ttaattagaa tgtatgaagt tattcaagaa aatcgcaata
    65221 gtattgctat agagaaagct gatttacaag aactagtttc tgatatatct catcaaatta
    65281 aaactcctat tgcaaattta aaaatgatta atactactct actaaatcaa acatttaaaa
    65341 cagaaattca aaaggatttt ttaatggata tggaaaacca attagataaa ttagattttt
    65401 taatgcaatc tatggtaaaa acctccagac tagagacagg tataatcaca ctatctaaaa
    65461 agaaaaattc aatttatgaa acaattgcta cagcacttag tggaattttg tttgatgctg
    65521 aaaaaaagaa tattgaagtt acagttgatt gtgacccaaa tttatatata attcatgaca
    65581 agaaatggac ttctgaagct atttttaata tattagataa tgctgtaaaa tacacaagtt
    65641 ctaatggtaa gatacgtgta gctacagaat gttgggttat gtatacaaaa atagatatta
    65701 ttgataatgg aaaaggaata tcagaaagtc gccaagcaga aatctttaaa agattttatc
    65761 gtgaagaaga tgtccatgac atagaaggta ttggaatagg tctctatctt tcaagaaaaa
    65821 ttatatctct tcaaggtggc tatattaaag ttacatcaga tattggaaaa gggtcgactt
    65881 tttctatttt cttacctaat aaataaattt ttaaatattt catttgtaat gattctgcaa
    65941 cattttggtt ttatactgta tttacaagat gttaaggagg tattattatg agtattttac
    66001 aagtaattaa tttaaagaaa tattatggac aaagttcaaa cattacaaaa gctcttgatg
    66061 gtgtaactct atctattgaa aaaggcgaat ttatttctat tgtaggtaca tctggtagtg
    66121 gcaaatccac attattaaat atgatgggag gattagataa tcctacatct ggaaaggtta
    66181 ttataaaggg taaggaatta tctactatgt ctgatgaaca gcttacaatc tttagacgca
    66241 gaaatatagg ttttatattt caaaattata atcttgttcc tttacttaat gtatatgaaa
    66301 atattatctt accaatagga ttggatggag agaccataga taaggatttt ataaatgaaa
    66361 ttataaatat gctttctctt gaagaaaaat tatatgatat accaagtaat ctttctggtg
    66421 gtcaacagca acgtgttgct atagctagag cacttgtaac aaaaccagct attatactag
    66481 ctgatgaacc aacaggtaac cttgatagta gaactagttc agatgtactg agtttactta
    66541 aagtgacaag taaaaaattc aaccaaacaa ttgtaatgat tacacacaat aatgaaattg
    66601 cacaactaac tgatagaatt attcgtattg aagatggaaa aattgttaac taggaggtgt
    66661 agtatatgtt tagaaataat aatcgcacat ttataagaaa aatagcttta aatgatttaa
    66721 aaattaataa acttaaaaca tatctttcag gtatcattat aatgatttct acatgtttat
    66781 tattaacagt gaccttagtt tcatataatg cctctgtaga tttagttaat gcatctccat
    66841 atcatgctat atataaatct gtagatgaaa aagcaaaaaa tatactatat aaagataaaa
    66901 actttagtgg cgtaggaact tacaaattaa ttggaagtaa taaaaagaca gattgtatta
    66961 tgtcgattgt ttatgcagat gatacagcaa ttaaacttat gaattttcaa ccattgaaag
    67021 gcaaactacc tacaaataaa aatgaaattg ctatttcaga aaaatattta caggaatttg
    67081 gtttagataa agatattgga gatagcatta aattaaatta ttatgatgat attacgaata
    67141 aagaagttca atgtgatttt attattgttg gatttctaga aaattattat caagataatg
    67201 ccaagcaata ctatacagtc gtttcaaatg attattttaa gaatatagct tctacacctt
    67261 tacaaaataa aagtaatact tttgacgagt caagacctga tactgtagat gtattagtta
    67321 aactatcaga agaaaataca gagaaagatt cagcttcaat taagacacag ttaaataaaa
    67381 ttggtttatc tttaggtatt aagaaatata atatatactt aaatgataac tatattgaat
    67441 caaatttaat tgatggtgag cagattatta cagttttagt agttggaata gttgttcttt
    67501 tttctagcgt ttttgttata tatagtattt tttatatttc agttgttaat tcagttcaga
    67561 tgtatgctaa gttgaaatcg ttaggtatga cttcttttca gttaaaaaaa attatttctc
    67621 tacaaggaaa tattttgtca attattttta ttccattagg ggttatagct tcttgtataa
    67681 ttgcttacat aattcaacca ttagcatggc aaatgatagc tgatttattt ataattttaa
    67741 ttttatcact ggtaatgttt ttaactgtta gaatttcttt atttaaacca gctagaatta
    67801 tttctaaaat atctgctatt gaagccatgc aatatacaga aactaaattt agaaaaaaag
    67861 caaaaaattt tagttatata aatataaaaa atctagcatt aaagaatatc gagtcaaata
    67921 gaaagaaaaa tttgattgca ttaatatcgc taagcattag tggagtttta tttatttcaa
    67981 tcgctaatct tgctaattca atagatttca aaaaacaact atctcaacaa tttgtctata
    68041 acgaagatta tataattagc attaagagtg ataacttata tgagcatatt acagaaatcc
    68101 aacaaaataa tccactaaca gattctctta agaatgaaat taaatctatt catggagtaa
    68161 aaaaattaat tgaatccaaa tcaattaaaa gtaatattat agaaccttac atcaaagata
    68221 gagacgaaaa acaatttatt actctaatta aaggtattac gcctgaactt tcaaaatcac
    68281 ttgaagaata tattgtcagt ggaaaaatag actatacaca tttagattca gatagtttaa
    68341 ttataaataa atatagaaca aaatattatg gattaaattt aaaagttgga gatacagtta
    68401 catttaatat ctttagtgga aatgatatta ttaaaaagaa aatgaaaatt ataggaatca
    68461 ttgacaattc caatacagga ggtatgtttt ttgcttcaga caaaacttta gaatctctaa
    68521 caccatataa tacaaattta gatttttcta ttttaataga taaaaagcat tctaaagaag
    68581 ttgaagaaaa gttgttaagt ataattcaga aaaattcaaa tttaatgctt tattcatatg
    68641 aagatgatta tagaatgatt actagagcat ttcaatatat aattatagct tcatacattt
    68701 ttgttggttt aatttcttgc tttggtatac taaatatgac caatacccta ataaacagcg
    68761 ttttaattag aaaaaaagag tttgcattac ttcaagccgt tggaatgaca agaaagcaac
    68821 tgcgaaatat gctttataga gaaggtctaa acataagtat caaagctata tgtacttcaa
    68881 gtatactagg ttattttggt tcaaatctac tttgcacttt tataaaagat gtaattagat
    68941 tagactttat taattttaaa ttttctatat ttactatttt aattttttca ttcgtattaa
    69001 ttggtataca agttttagtg actgaattac ttgtaagaaa tatagaaaaa aaatcactta
    69061 cagaacgctt acgttctcag taagaatgta tataaaaaat agccattttt tatacaagtt
    69121 ttaacataat tttttaaaag ctaaaaggat agaaaatttt gactttacat aattttctat
    69181 ccctatactt gtttttattt tatacagata cacttactta tatctccgag caacatcacc
    69241 agagacataa acaagcatat tccttatttt ctaaatatgt caattgcatg acttgtaacc
    69301 cctactaaat cttcacgttc acaagtagca aggtgatatt ttaaatataa tgcaaatgca
    69361 tcatcatcca tagagtctac tgcttcacgc atatacaaag ccaaaccatc tgatgcgaca
    69421 taatgcagtc tagttacatt aaatgcagac atcaaatcat caatgttttc tttacgtaca
    69481 agctcaaaca aatcctttgg ttcagactta gcagcaaatg tctgtggatc aatcaaacct
    69541 ttttcaatat attcagatac attaatattt cctctatgga acccctcgtc aataagacag
    69601 ccatcagata taacatatgc agcaaaaacc acaccaccag gttttgttac acgaattgcc
    69661 tcatgtaaag cttgttgttt atcttctttg ttataaagat gatatagtgg tcctaacagt
    69721 aacgtaatat catatttatt atctgggaaa acagataaat ccatagcatt accctgagta
    69781 atgcttatat tttcatttga ttgagtattt ttatggaaaa cctctatatt atgttcgact
    69841 aattccactg cgtcaacatc atatccctga cgtgccagtg tgtgagaata acgaccagtt
    69901 gcagcgccaa tttcaagcac acaatcacct gattttatgt acttatcaat gtaatgcata
    69961 gtagtgagaa attccaccat tccatgtttt aatgcaagtc gactatcttc atcataagta
    70021 ttataaaagt caattaagta ttgttttgtt tccataattt cacctcttct atattagtta
    70081 ataaacatca aatagacaaa ttccaatctg atttttcttg tcttataaaa gctgttaata
    70141 tatttttcaa cattttttca gcactatatc tatctaatgt taattttttt gttgctgtta
    70201 agacagctat gccatgagta taaagaaata aatctaaaaa tattactttt gcacattcca
    70261 aatctattcc aatgctttcc gaaaaaagtc ttgccttttt ttcattgtca atttctttat
    70321 aaaaatcatt cgcctctttc atcatcaaat ctaaatcatt tataaataac aacttaaata
    70381 aatacgtttc ttcttgagca aattcaatgt atgaaagcgg aagcagtaaa taagggctta
    70441 cacttttaga attacgataa ttaacaacat actgattata atattcatat gcaaaagcaa
    70501 gaaattcatt ttttaattca ttcatgtttt cataacaagt aaaaattggt cgagtggaac
    70561 actgtaattt acttgcaata ctcctcgcat ttacagcttc aaatcccact tctcttgtaa
    70621 tatccaagac tgtattcaaa atcatttctt ttgttatctt tactttaggt ggcatatatg
    70681 ttcacctctc cattaaattt ttataaaaca catgtgttat ataactatag taacatatca
    70741 agaaattatg tcaagaaaaa gctttgcatt tttttgcaat tcctaaaact tataaataaa
    70801 acatgagttg caattaatct attaatagat aacagcaact cagattttcc tttaaatact
    70861 cttctttttg tctaatattt catatacaca atcttctatt gaattaatat ctttttcttt
    70921 tcttttttta gaatcaatta aaatgaaata cagtataaaa cctacagcaa gtccccatgt
    70981 tccgccttta gcagcaatta cacctcccat aagtccaatc aatcccttct caacacctgt
    71041 attacatagc tccattgata gctttgtaca taaatatcct tgaactaaaa gtgttactga
    71101 caatgctaat ggtataagag gtgtagcaat ctgcgcaatt ggataaaaac agataaaaat
    71161 tgctgaaacc catactaatg tacccatgcc actaaaaaca gactgcatgg cttcctttcc
    71221 aaccttgtac ctttgagcaa cacttcctgt aagtgtcgca gctaatggac cgcacattgg
    71281 tatatatgga gaaaagattg ccataaaaat atttcttatc ccacttataa cattagacct
    71341 atttgaattg aaatctatat attcatcttt tctattttca ctttcagaaa gtactaagtt
    71401 ttcacctgtt ataaaatcac caaaggcaat tatgtatatc ataaaagcca ttggtatccc
    71461 ttgtataaat aacattacac ttggaaaacc tattccaaaa ggagatactg tatttatcag
    71521 atttttaaaa tctactatgt aaactaaatt gtcaaaacta aatctaggaa tttctatttc
    71581 tttactaaat atacctacta ttaaactcac taaaatagct gatactacac catattctcc
    71641 taaatgaaat aaaaatttat tcttaacttt tagagtatca aatctttcag aaaacattac
    71701 aaaacaagca accaaaattc ctactgttat agatatagga taagaatcaa atctcccttt
    71761 aggattaaac tctgatatta tagtcgatat accgacaccc attagtattc cacctttaat
    71821 agaatttggt atcttactaa ctaactttcc agctacacca gttataccca ttaaaataaa
    71881 tattattcct aaatctattt gtaaagctgt taatgcttgt attctttcaa tgcccatgct
    71941 gaactttaac aaatatgcag ttgtaagagt tatagaagct gtaatccagc caggtacaac
    72001 tgggtctccc ataaaaacat gcaaacagta taatattgag ttaatgatag ccatactcca
    72061 tgccacttca tagggtaatc ccaaaatttg tgtactaagg ccaattgtgc ctaaacttgt
    72121 catacttgat attatacctt gaatagcttc tggtttctca aatctgtaat gtataaatgg
    72181 aattcttatc ttaaacattc caaattttat atgaggttgt tcccttctag cgagtctttc
    72241 cataacttca ctccaccttt caataactct tataagttta caactttata attgtttata
    72301 aattatcaat gtcattaaaa ttagtatata acatgcaaat tatataaaca ataaattaaa
    72361 tctataaaat tgatagattt tgtgcatata tagaaagacc gcttcatttt tagttactta
    72421 aatcacttaa tagtagttat ttaaatcact tgataaaggt tttttataaa attcaatagt
    72481 tctattccat gattcaaact gtccttttga atttccttct acagttccac ctgaagaaaa
    72541 aatccctcca ctcatactca tacataaagt ctcctttaga ggcataatat atggaattgg
    72601 taacggatga cccatattat tgtatgttaa taattctacg ttatatggat aattattttc
    72661 ttcaaagatt tctaatgcct ttaaacaagc ttcataacta ttccatatgt tatcttcttt
    72721 tccagcaatc ataagtatat ctgctttgga attttctatt tttattctag cctcttttct
    72781 attctctgct cttttaagac ttttcttata agtactatta aatccaaatg gaataccttt
    72841 tgatatattt tttttctgtt cttcaaagaa tatatcattg tctactttga tatatggaaa
    72901 tggctctcct ttatatgacc atgatgaagt atcatttcca ctcatcaatc cattaagagc
    72961 ttggaaacaa taaatgtgag gttgtgatac tacaaccttt ttaatttgtt catatcttga
    73021 agcaagtaaa aaggccaatt ctccaccctt tgatgtccca tgtacaaata tttctttagt
    73081 actggtaatt tcattttcac taatccactc aaatactttt tcaaaatatt ctaatggaac
    73141 ctcttctaat ttatctggta acccttctaa agcaaagtat gcaactgtta gtacattgaa
    73201 tcctctagat gcaagtggag ctgctaaaag gtctagagcg tctaaatttc catcagaacc
    73261 acctagcatt aaaattgttt tattattaga attttgttta taaaataatt ttcctataaa
    73321 ctcatcagat atatattttg tggtaatatc ttctgattta aatattctct ttaattcaac
    73381 ttcttttctt tcaatagaag tttcaaatat catattcata attattggtt tatcaataga
    73441 tatattttct gcaaaatttt taccttcagt tttagatttt tccagcgaat aaattaaccc
    73501 catacaatta tcagccttat aagtaccttc tataggttca actaaatcta aatctacttc
    73561 tcctttttca tttgaacaaa acactccata agatgaaaat tcttctccct tgcaccatgg
    73621 aaattccatt ttcacactta ttttaagttt agtatttgga attaagtccg aaaccataat
    73681 cttaagtctt tcatccacaa atgattctac attgtataca tttactttca taatctattt
    73741 ctccttataa taattattta tgttttatat aaaacagctt tatctaatac aacataaata
    73801 aatttttaaa ttaagacacc atattgacta tttcatttta tcaacatatt ctatttttgt
    73861 caacatattg tcttttttag caatttaaaa ttatgtagtc tatatgaaat ccagttgatt
    73921 tttggctaat taaagatagg aatgctatta ggtttagaat atatatattc aaaataaaaa
    73981 accactcatt ttaagaatgg tttttaatat aaactatttg ttattaataa ggatattttt
    74041 ttatttaaat ttatataatc gaacatctaa tatttaatgt ttaataaaat tatgcatttg
    74101 caaaagtata tatggcatta actcttgcta catataaatt ctcatcacta catccaatat
    74161 atctagcata tttttcaatc ttttcttttg cattttcaac atcattttca tcgctctcca
    74221 ttaactcatt tatataaata tccattaatg acgctttata ttctcttata tcatagccta
    74281 aaaattcagt caatctctca atttccttac taaaatctcc atcttctttt accaaaaatt
    74341 cgtatacatc ttccctatat ggatttaaag ttattatttg ttttactact ttgcattcgt
    74401 cagccttccc aataaaacca tctttataat tattaaataa ggcattagat ttttttatag
    74461 attcttcatc aatataagaa tgtaccgcag ttatacgatt ttctataagg gcatctacaa
    74521 cagcataatg aattttaaaa caatcattgt ataaataatt gctcattttc tttattgtcg
    74581 attctatttc taagaagctc gcgtggccat tttttttatt tttatttggt ataataaaag
    74641 ttttattcaa gttattaaaa agtctcttaa aatctaaata tttttcacaa taaacacttt
    74701 taaaggtatt gatatctata gttataattc caaaacttac tatagtctca attcctttct
    74761 taaaagactc ttctatatat ttttctccta aacttaaacc tctatcagat atttgcttta
    74821 gattttgaaa actatttaaa caatctctct caaagttttt agatatttcc aaagcatata
    74881 atttaaagat tttccttatc ttattataat tattttttgt atcatcaaat ctgataatag
    74941 ctccatttac atcaaaagta atcattgagt tttaacctcc ccattagttt catcaataaa
    75001 ataaatttaa tataaacttt ataatcataa tattaaactt atttatacta taa
//
LOCUS       DAEHWO010000010        73395 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEHWO010000010 DAEHWO010000000
VERSION     DAEHWO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 73395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73395
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.010"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(381..1103)
                     /locus_tag="KNP54_000896"
     CDS             complement(381..1103)
                     /locus_tag="KNP54_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBF0891819.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(1162..1839)
                     /locus_tag="KNP54_000897"
     CDS             complement(1162..1839)
                     /locus_tag="KNP54_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBF0891820.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(1867..2682)
                     /locus_tag="KNP54_000898"
     CDS             complement(1867..2682)
                     /locus_tag="KNP54_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBF0891821.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(2908..3118)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3836..5902)
                     /locus_tag="KNP54_000899"
     CDS             complement(3836..5902)
                     /locus_tag="KNP54_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBF0891822.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(5979..9008)
                     /locus_tag="KNP54_000900"
     CDS             complement(5979..9008)
                     /locus_tag="KNP54_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0891823.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(9061..10521)
                     /locus_tag="KNP54_000901"
     CDS             complement(9061..10521)
                     /locus_tag="KNP54_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBF0891824.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            complement(10613..10987)
                     /locus_tag="KNP54_000902"
     CDS             complement(10613..10987)
                     /locus_tag="KNP54_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891825.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            complement(11163..11903)
                     /locus_tag="KNP54_000903"
     CDS             complement(11163..11903)
                     /locus_tag="KNP54_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBF0891826.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(11924..12712)
                     /locus_tag="KNP54_000904"
     CDS             complement(11924..12712)
                     /locus_tag="KNP54_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBF0891827.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(12800..12890)
                     /locus_tag="KNP54_000905"
     tRNA            complement(12800..12890)
                     /locus_tag="KNP54_000905"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12854..12856),aa:Ser,seq:gct)
     gene            13149..13913
                     /locus_tag="KNP54_000906"
     CDS             13149..13913
                     /locus_tag="KNP54_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBF0891828.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(14194..15309)
                     /locus_tag="KNP54_000907"
     CDS             complement(14194..15309)
                     /locus_tag="KNP54_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBF0891829.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLIFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(15350..16876)
                     /gene="glpK"
                     /locus_tag="KNP54_000908"
     CDS             complement(15350..16876)
                     /gene="glpK"
                     /locus_tag="KNP54_000908"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBF0891830.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            17169..18266
                     /locus_tag="KNP54_000909"
     CDS             17169..18266
                     /locus_tag="KNP54_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBF0891831.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRY
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            complement(18757..19269)
                     /locus_tag="KNP54_000910"
     CDS             complement(18757..19269)
                     /locus_tag="KNP54_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891832.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            19822..20703
                     /locus_tag="KNP54_000911"
     CDS             19822..20703
                     /locus_tag="KNP54_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBF0891833.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKSVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(21016..21795)
                     /gene="hisJ"
                     /locus_tag="KNP54_000912"
     CDS             complement(21016..21795)
                     /gene="hisJ"
                     /locus_tag="KNP54_000912"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBF0891834.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNKILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLDLVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(22341..22691)
                     /locus_tag="KNP54_000913"
     CDS             complement(22341..22691)
                     /locus_tag="KNP54_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBF0891835.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(22707..23123)
                     /locus_tag="KNP54_000914"
     CDS             complement(22707..23123)
                     /locus_tag="KNP54_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBF0891836.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(23142..23333)
                     /locus_tag="KNP54_000915"
     CDS             complement(23142..23333)
                     /locus_tag="KNP54_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBF0891837.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(23484..24299)
                     /locus_tag="KNP54_000916"
     CDS             complement(23484..24299)
                     /locus_tag="KNP54_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBF0891838.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(24346..25284)
                     /locus_tag="KNP54_000917"
     CDS             complement(24346..25284)
                     /locus_tag="KNP54_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0891839.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(25281..26153)
                     /locus_tag="KNP54_000918"
     CDS             complement(25281..26153)
                     /locus_tag="KNP54_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0891840.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(26178..28106)
                     /locus_tag="KNP54_000919"
     CDS             complement(26178..28106)
                     /locus_tag="KNP54_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBF0891841.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(28218..28595)
                     /gene="gcvH"
                     /locus_tag="KNP54_000920"
     CDS             complement(28218..28595)
                     /gene="gcvH"
                     /locus_tag="KNP54_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBF0891842.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(28682..30808)
                     /gene="cdhC"
                     /locus_tag="KNP54_000921"
     CDS             complement(28682..30808)
                     /gene="cdhC"
                     /locus_tag="KNP54_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBF0891843.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(30865..31671)
                     /locus_tag="KNP54_000922"
     CDS             complement(30865..31671)
                     /locus_tag="KNP54_000922"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBF0891844.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(31721..33088)
                     /locus_tag="KNP54_000923"
     CDS             complement(31721..33088)
                     /locus_tag="KNP54_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBF0891845.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(33119..34063)
                     /locus_tag="KNP54_000924"
     CDS             complement(33119..34063)
                     /locus_tag="KNP54_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBF0891846.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(34083..34853)
                     /locus_tag="KNP54_000925"
     CDS             complement(34083..34853)
                     /locus_tag="KNP54_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0891847.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(34909..36294)
                     /gene="lpdA"
                     /locus_tag="KNP54_000926"
     CDS             complement(34909..36294)
                     /gene="lpdA"
                     /locus_tag="KNP54_000926"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBF0891848.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTIKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(36338..37219)
                     /locus_tag="KNP54_000927"
     CDS             complement(36338..37219)
                     /locus_tag="KNP54_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBF0891849.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(37254..37928)
                     /locus_tag="KNP54_000928"
     CDS             complement(37254..37928)
                     /locus_tag="KNP54_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBF0891850.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(37965..38837)
                     /locus_tag="KNP54_000929"
     CDS             complement(37965..38837)
                     /locus_tag="KNP54_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBF0891851.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(38929..39561)
                     /locus_tag="KNP54_000930"
     CDS             complement(38929..39561)
                     /locus_tag="KNP54_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBF0891852.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(39666..41342)
                     /locus_tag="KNP54_000931"
     CDS             complement(39666..41342)
                     /locus_tag="KNP54_000931"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBF0891853.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(41591..42370)
                     /locus_tag="KNP54_000932"
     CDS             complement(41591..42370)
                     /locus_tag="KNP54_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0891854.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(42680..44599)
                     /gene="cooS"
                     /locus_tag="KNP54_000933"
     CDS             complement(42680..44599)
                     /gene="cooS"
                     /locus_tag="KNP54_000933"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBF0891855.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKSGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(45206..46117)
                     /locus_tag="KNP54_000934"
     CDS             complement(45206..46117)
                     /locus_tag="KNP54_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBF0891856.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(46233..46811)
                     /locus_tag="KNP54_000935"
     CDS             complement(46233..46811)
                     /locus_tag="KNP54_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBF0891857.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            47037..47960
                     /locus_tag="KNP54_000936"
     CDS             47037..47960
                     /locus_tag="KNP54_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0891858.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(48132..49274)
                     /locus_tag="KNP54_000937"
     CDS             complement(48132..49274)
                     /locus_tag="KNP54_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBF0891859.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELRINK"
     gene            complement(49292..51046)
                     /locus_tag="KNP54_000938"
     CDS             complement(49292..51046)
                     /locus_tag="KNP54_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBF0891860.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            51182..51388
                     /locus_tag="KNP54_000939"
     CDS             51182..51388
                     /locus_tag="KNP54_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891861.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(51393..52316)
                     /locus_tag="KNP54_000940"
     CDS             complement(51393..52316)
                     /locus_tag="KNP54_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891862.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(52570..54270)
                     /locus_tag="KNP54_000941"
     CDS             complement(52570..54270)
                     /locus_tag="KNP54_000941"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBF0891863.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(54732..55145)
                     /locus_tag="KNP54_000942"
     CDS             complement(54732..55145)
                     /locus_tag="KNP54_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBF0891864.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(55213..57591)
                     /locus_tag="KNP54_000943"
     CDS             complement(55213..57591)
                     /locus_tag="KNP54_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBF0891865.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            57910..59361
                     /locus_tag="KNP54_000944"
     CDS             57910..59361
                     /locus_tag="KNP54_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBF0891866.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(59565..62078)
                     /locus_tag="KNP54_000945"
     CDS             complement(59565..62078)
                     /locus_tag="KNP54_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBF0891867.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPLEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIVMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(62301..63122)
                     /locus_tag="KNP54_000946"
     CDS             complement(62301..63122)
                     /locus_tag="KNP54_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0891868.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(63640..64116)
                     /locus_tag="KNP54_000947"
     CDS             complement(63640..64116)
                     /locus_tag="KNP54_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBF0891869.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(64150..64728)
                     /locus_tag="KNP54_000948"
     CDS             complement(64150..64728)
                     /locus_tag="KNP54_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBF0891870.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(64832..67414)
                     /locus_tag="KNP54_000949"
     CDS             complement(64832..67414)
                     /locus_tag="KNP54_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBF0891871.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSSISMDLYTSSSLGIPKELMGSNTNNIYTLSNTSKIDTLNKNHSNTA
                     VTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNIDCYLNA
                     FNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVTEYCPMG
                     VVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLDNLYELE
                     EIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKRATDLYKKLDEIGTVAGHYY
                     KGVE"
     gene            complement(67984..68667)
                     /locus_tag="KNP54_000950"
     CDS             complement(67984..68667)
                     /locus_tag="KNP54_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBF0891872.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(68992..69582)
                     /gene="zapA"
                     /locus_tag="KNP54_000951"
     CDS             complement(68992..69582)
                     /gene="zapA"
                     /locus_tag="KNP54_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBF0891873.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(69607..72000)
                     /locus_tag="KNP54_000952"
     CDS             complement(69607..72000)
                     /locus_tag="KNP54_000952"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBF0891874.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(72017..73036)
                     /gene="pheS"
                     /locus_tag="KNP54_000953"
     CDS             complement(72017..73036)
                     /gene="pheS"
                     /locus_tag="KNP54_000953"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBF0891875.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(73086..73320)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        22795 a        13757 c         8038 g        28805 t
ORIGIN      
        1 ttatttttac tataaaagtt aaatttataa gcttacttgt tataaaaata acttttataa
       61 tttatttcaa aaaaaatatt gatttttgtg tcgcattttg ttataataaa ttaaggttat
      121 ccccctggta accctagtta gttaatatat ctattcccaa taccctttca taaggatata
      181 ttttatattt attaaaaatc ggattagtaa cggaaattaa ttcggtggaa aaaaagagct
      241 taccccgagc tctttttttt ctgcaaaaaa tcgtaaaaat aaagttaata ttaatataac
      301 tttaatttta aaattaatat taaccatcac taaaaaagga tgtattgaat ttctaatatc
      361 aataacatcc tttttatata ttatagcact tttgctaaaa atgcttttgt tctttcatgt
      421 tttggatttc cgaaaacttc ttctggagta ttatcttcaa gtatacttcc tccatctata
      481 aaaataactc tatctgcaac ttccttagca aatcccatct catgagttac aattgccatt
      541 gtcatacctt ctttagcaag ttcttttata acatccaaaa cttcgtttac catttctggg
      601 tcaagagcag atgttggctc atcaaacaac atcatatctg gttccatagc aagtgctcta
      661 gctattgcta ttctttgctt ttgtcctcca gataattgtg atggatatga atctttttta
      721 tctaaaagac caactctact caacaaaatt tctgcttttt tttctgcttc ttccttagtc
      781 atctttttta atttaattgg tgctaatgtt atattatcta aaatagtctt atgtgggaat
      841 aaattaaagt tctgaaacac catacctata ttttgtctaa cctcatcaat attagttttt
      901 ttatcgacca aattttttcc ttcaaatatt atttctccac ctgtaggtat ttctagtaaa
      961 ttcatacatc taagaagtgt acttttacca gaaccacttg gacctactat aaccattatt
     1021 tcgcctttag cgatttctaa gtctatattt tttaatacat ttaaatctcc aaaagattta
     1081 cttaaatttt ttattgtaat catattatca ctttcctttt tactattcta tgttttccct
     1141 aaatgctaaa catgctctca tctagttaga cacagatagt ttcttttcta ataatccaac
     1201 taatcttgat agagtaaatg ttataacaaa gtaaattgct gctgctacta ttaatggctc
     1261 taatgctcta aatgctgcat tttttactat atcagcagta cgcattatct caacaactcc
     1321 tattacagat attattgaag attcttttac aagtgtaata aactcatttg ctaatgaagg
     1381 taatatattt tttatagctt gaggtattat tatatatctc atagttgacc aataatttaa
     1441 tcctaatgat ctacttgctt ccatttgtcc attatcaact gattgtatac ctgatctaag
     1501 tatctctgcc acgtatgcac cagagtttac tgataatgca aatgcactag ctataaattc
     1561 acttggtata ccaaacaaca tagggaatct tattcctaat tgaggtaaac caaaccatac
     1621 tatatatatc tgtactaata atggtgtccc tcttaaaacc tcaatataga ttgatgatat
     1681 tgctcttaat accttgctct ttgatatttt tgccatacag ataattatac ctattataaa
     1741 tccaaagcat aatgccacaa gagaaattga tactgtcaca cctgttcctt ccaaaaaaga
     1801 agtcccaaat ctacttaaaa aactaaaatc taaactcata atttcatctc ccacataact
     1861 ttcttactaa tttgaagcag cttcagtaga tgcttcattt aaaaattctt ctatcttctt
     1921 gccatcttgt aattctttta tctttttgtt taataattct ataaaatctt tgttattgtc
     1981 agattttttg attgctgctg ccataccttc tgttacatct ttcccaactt cagtatttgc
     2041 catttttatt ccatcatatt ttttaacatt tattaaagaa actgcttcat tagtaacaac
     2101 tgcatctatg tttccatttt ttaattctgt aattaaatca ggtattgctt tcaaagattt
     2161 tgtagttgtc atttttaaag tgttaactac atattcttct tggatacttc ctgcttgaac
     2221 tccaactcta agtttcttta aatcatcttc agtttttact ttgtctatat ctgcatcttt
     2281 aactataact gcatttctac ttaaataata taattctgaa aaatcaacac tcttttctct
     2341 ctctggtgtt ggagacatac ctgcaagaac aatatcaact tggtctgcat ttaaagcacc
     2401 tattaatcca tcaaatgaca tatccttaat ttcaaccttt acaccaagct cttttgcaaa
     2461 ttcttcagcc aacattatat cgaatccttt tattgaatct tttccatcta ctaccttatg
     2521 aaattcaaat ggaggaaatt ctgcactagt accaacaact aattttccat tgtcttttat
     2581 ttgttctaac tttgtttttt ctcctccacc actacatcct actagcgata atgtcaatcc
     2641 taatactaat cctaaactta ataatttttt aaatactttc attttaacta cccctctctt
     2701 ttaattataa tttccctcag attttaatac ttaaatgttt cgagttacaa aaaaagtctc
     2761 tcagtcttta atgactaaga gacgacttta ccgcgttacc actcttattg ataaatactt
     2821 atattacttt caaaatttgt gactgttagc atttaagctg tatggatact tttattttta
     2881 aatcaaaaaa gtcccttagc tttacagcta agagacgaat tatatccgcg ttaccactct
     2941 ttttgataag taagtactta tcctctcaat cccttaaggc gggtaaacca attatcatac
     3001 taaagtttct gataatctcc tccagagctc tcttcacata gacttcattg ctaggcttac
     3061 accaacccct aactcgctgt aaatccatat atgctacttt ctctatcatt ggatttgttt
     3121 ccttaaattg ttaatacaat tgtacttcct tataatattt ttgtcaataa gttttttatt
     3181 tttttaataa tttttacttg taaattatct aaatactact gtttatattt attgatatta
     3241 gttttgtaat tataaatagt atatttcata tttttagata tttcttaaat aatactaaat
     3301 aatatctttc acattgttgc tttttcttaa acaatactaa ataatatctt tcacattgtt
     3361 gcttttctta aattacacta aataatatct ttcacactgt tgctttttct ttaataatac
     3421 taaatagtat ctttcacact gttgcccttt ctttaataat actaaataat atctttcaca
     3481 ttgttgcttt ttcttaaatt acactaaata atatctttca cactgttgct ttttctttaa
     3541 taatactaaa tagtatcttt cacactgttt ctctttcttt aataatacta aataatatct
     3601 ttcacattgt tgctttttct taaattacac taaataatat ctttcacatt gttgcttttc
     3661 tttaataata ctaaataata ttttccacat tgttgctttt tctaaacaac tataaataat
     3721 atattaaacc cttatttctt tttctaataa gttaaataat acattttaca catatctatt
     3781 tgtcttgcac ataataaata atacattata tttctatcta aatttagatt ctaaattaaa
     3841 tagtataaat tatattcttc aataaacaag ttttcaaatc caagattcgc tctctatctt
     3901 taaactttat tgtaaacata attccatctt ttttaattat ttctccttca tgaaattttt
     3961 tatggtatac cttatcccct acaccaatac tgtcaatttc ttttttcgtt ggagatttta
     4021 tatcattaat aaataatgat ttatcaactt tcttaccata cttatttaaa gtagagctta
     4081 tacataactt ttcttcagct cttgtaatag caacatacat aagtcttctt tcttcttcta
     4141 attgttcttc ttttttctct tccttacaaa tatcatatga tttttcatga ggtattgttc
     4201 cttcatttac acctataata taaacatttc taaattctaa tccttttgca ctatgcatag
     4261 ttgtaaatat gacaccctca gtctgcttat tcttgttatt ttccgttaac tcagtcttta
     4321 ctctatcaat atgctctaaa aactctgtaa cagtattaaa attagttgct gaactctcaa
     4381 gttcatttaa tatctctaca agtccattag tctttatctt tctgttgcta caataatcta
     4441 aaacatatct atcataatca agactagttc taatataaga tattgcattt ttaggattta
     4501 aagtatttaa ataacttaaa tctatttcca aatcatttat tgttttaact tgtttaggat
     4561 gaagattaca cttatttatt aatgctgtta taaagtcttt ttcatcctta accatattta
     4621 tactgtcttt ggatatatat ctaaaaggct tgtttataat tctcaaccaa tctttatttg
     4681 attttggatt aatacctatt cttaaatagg ctagtatgtc ttgacttgcc caatggtcat
     4741 atattgtaat tactgagtct tttactacaa atggaatcct catatccata aatacatcta
     4801 ctaatgctct tgactgtata ttagttctat aaattactgc aaaatctgaa tactctacat
     4861 aatctttttg tatttcgtca attatttccc tggcaatata taaggcttct tcctctgaat
     4921 catgcggaga aatataggta acacttcctc catccccctg actacactta atgatttttt
     4981 catatctatt tttatttttg tcgataagtc tatttgcagt atgaactatc tcacttttag
     5041 acctgtaatt tatatctaat attatttttt tagtattatt aaagtattgt tcaaattcaa
     5101 gcaaaaaatc tggtctagca cctctaaatc catatatact ttggtcttca tctccaactg
     5161 caaatatatt gtttaatggg ctacaaatta actttaaaac ttcaaactgt actttattta
     5221 tatcttgaaa ttcatctatc aatatatatt tatacacatt tctaaccatt tctagtgcag
     5281 acttattgtt caaaagtaaa taataagttc ttataagcat atcatcaaaa tctattttat
     5341 taactttaga tttttgttct tcgtataagt tgtatacttt taaaaactca tcttttgtta
     5401 atacttctga attaaattca tttttatcca taagttcatt ttttacatag gaaatttcat
     5461 ttataacttg tcctatattc tcatcatcat cagcattctc tatatttaaa ctttttagga
     5521 ttgccttgat tgtcattcgc tttgactttt catcaaatat actgtctaag ttgtatcttt
     5581 caaagtatct tagaatttta aaaaatacag agtgaaaagt accataggtt accttattaa
     5641 gtcttatgtc atcacttaaa ttcaaagctc tatttttcat ttctattgaa gatgccttgg
     5701 taaaacttat tgccaagatt cttgttggtg ctatgttttt gtttacaacc atattggcta
     5761 ttctatatgt aattactctg gtcttacctg aaccaggccc tgcaagtatc atgcaaggcc
     5821 catctatatg ctcaactgct tctaattgat tttcatttaa ctttcttata tctatatttg
     5881 ttgtgattat tagctccacc accttgattt ataattatat tattttcttt ttaattataa
     5941 actaaaagtt cataaaaata aatttaattt ttcctctatt aaaccacatc attcctattt
     6001 tcatgacata tcttgagttc ttttttaatt ttgtcgctta tatcttcagg tataaatgat
     6061 ggtttactaa tatagtagcc ttgcatataa tctactccaa gattaattag tgtttccatt
     6121 tcaccttttg tttctacacc ttctgctatc actttaatat ttctttcgtt agaatatgag
     6181 ataagatttt ttaatatttt ctgtctgttt tcatctttat caatacctct tacaatagac
     6241 atatcaatct ttacatagtc tggcattata tataatagta cagcatctcc gttgtaacct
     6301 gtcccaaagt catctaaagc aatttctata ttccaatggt ctatatatgc tttctttttc
     6361 tcaataaaat cttcattaat cttatcattc tctgttattt ctagtactac tctatttaaa
     6421 tattcaccat ataaatcttc aatttcctca aaatctactt ttgacaaatt attattagga
     6481 atagaattta agaacagttt gcaatcgcca aatttttctt tgtatttttt aaatgattta
     6541 agtgctttaa accatgtaat acgctcaatt tgatataatt tagactgtga acgagctaat
     6601 ctaatgacat ctattggcga actaaaagtt tttattttag gtctcataag tgcttcatat
     6661 gcaaaaactt tacctttaca atctacaata ggctgaaatg catactcaac taattgacca
     6721 tcaattaact tgtttaattc ttctctatta ctcaataaga atgaatcctt attatatata
     6781 ttaatatcaa attcactaac ttcacccttg attgtatttt taatttgata catagcaaaa
     6841 tctgcgtatc tcattaattc atcatagttg gttgagtcat cagggtacca ggaaattcct
     6901 gctgatgccc ttattttaaa ttctgttcca tcatgaagtt ttaataaggt attattcatc
     6961 tgtttcttaa cagaattaat aatatctctt atactatctt tactttcata tccatatata
     7021 aatacataaa actcatcacc tgaaagtcta gatactatac cattccatga tataaacttc
     7081 ttaagtatgt ctgcagcaca cctaatatat tcatcaccag catcatgtcc atatgtatca
     7141 ttaatatatt ttagattatc taaatcccac ataataaatg ctgctatctt aagttcatct
     7201 ttattcttaa atttttcttg tatctgtgaa tgaaaagctc tcctatttaa aagattcgtt
     7261 aaaatatcaa aatctctttc atattctatc ttccttttct caataaattc ttttgttaca
     7321 tcaacaacaa caccaagaac ctttagctca tcttcaaaga tattcattct tatccactta
     7381 agttttttat ctttagattc aaacttatat atatatgtat tttctgtttc ataactttct
     7441 tgcaaatatt tatctagtcc ccttaatttt ttcaggaact tatttttttc catatatcca
     7501 tattcttcaa atttgatttc agtagtaaac acgctaaaaa attcttttgt acaaaaaaca
     7561 ttctctgcgt ttttgtataa ctcaaaagct ccaattggca tatctaccat ttcaataatc
     7621 tgtgataatt ttgacgaaga atctgcaaca tttgcactga gcaactctat agctgaagat
     7681 aattcatcta tttcagatat atttatctta tcaagattta ctggttttga tggattactg
     7741 tttctaactt tgttggctaa aagaacaatt ggttttgtaa ataatcttga tgcaatataa
     7801 atacctatta gacctattaa taaagaaatt gctatagata ttataactaa tttctctacc
     7861 ctttttgaaa atgacaaaag acttttttct tcaataatac ccaaaagagc ccaacgttca
     7921 ttttcaaatg gagtattgga gttatataaa tctaagtatt gtacactagc ataaatgttg
     7981 ccattaccac attcattatc tttattttta atcttatata tatttttata cgattccttc
     8041 tgctctaaat tagaatgtaa accatcccaa aatttttctt ttaatgagta tccatttgaa
     8101 attacatttt caaaggccat atcattattt ctatctacac ctaaaatata attacccttt
     8161 ttattcccat ttatctctga gtatggaagt aattctctta aataatttac acttaaatct
     8221 attccaagta ctccatatac agttccatct tcataaataa ggggaactgt atatgtcata
     8281 agcctatcac ctgcatttgt caataaaaac ttacttcccc agtatcctaa attagaactt
     8341 gatacatttg gattatcaat tgcagctcta aatggtttat aaaaaaaatc atctccatct
     8401 tgctcatttt cacttttaaa tgaaaactta ggttcccaat aactgtccat agatattcca
     8461 aaacttcttg ctatatctga tgaacctctc tcaattaaca aatcagaatt atcatttgga
     8521 ttaaacttag ggtctaaatc ccttatatac aatcctgtcc tacttatttc acctttacta
     8581 tctattgact tatcgttaat atttttgtca cttaggatta taaaagctcc tgtaacagaa
     8641 ttttttctca aaagatatat taaatcattt gatatgcttt ttataatatc tttgttaatt
     8701 tcttcattgt tgcctacatc ctcaattaag gcattttttt catttaatac tttttttaca
     8761 gaggaattaa ttgtagcttc cgtttcactt gtatttgacc atctttgtaa catttcattt
     8821 tgtatataat ttttacgatt aattactctt tcatttaaga tgtcaaacga attatcattt
     8881 aatttcttaa tagttcctcc ccataaaatt gtggcacaaa ataaacttgt ttgaattagc
     8941 ataacaataa ttaggggaaa tatcatcttt ttcattattg aattgttttt tcttagattg
     9001 ttttccatac ccattccacc tatacctttg tgctcgtcaa cacactaact gccaattcat
     9061 ctattttttt atagcatttt caagctcagc cttaaaactt tcaaaccaag ttttaaaatt
     9121 tttatcatta ttaaattgtg ctactgcatc cttcttagaa gttccacttt ttactaattc
     9181 atttatttta tttgaatctt ctttagcttt atcaagcatt gaatattcaa gtatttgtct
     9241 agctttagtt ccaccatcaa atgctttatt agtatataaa ttacaactgt taatctgttc
     9301 aatagatgag gctattgaac cttcaacttt atcagacaaa ctcaaattat ctttcttcat
     9361 aacttctttt ataacatcca aatcattcgt ttttttcttt actggtaagt atccagaagc
     9421 aatagagaat tttatattag gttctttatc tgtaaaccat tttaaaaatt ctactgatgc
     9481 atattcttct tctttagtag attttgttac agccattcct gcaccttgtt gtacagcata
     9541 ttttccttct cctttaaaac gtggtgcttg aaaaacagat gtttcaatat tataactctc
     9601 attatcattt agcattactc tatctggaaa gtatgctgct cctgaactag aacctacaag
     9661 agctaatata tcacctgttt ttgcatcatc agaacgaaac ttaccataag aagcaaaata
     9721 tccatttata tatggtacat agaaattatc ccatagtttt ttcataactt tttcatcaat
     9781 atttagcgta actttaccat ctttaacaga aaaaatttct actcctagtt gtttacttcc
     9841 tataataata taatttgcta aagcatctct tccaaaaaat gctttaccat cattaggctc
     9901 tttcgttaaa ctatctgtcc attcataata tttttttgat gtctctacta atccttcaat
     9961 tgtttttata tcatttatat ttgaatttgt agcttttgca aatttatccc aatcagtttt
    10021 atttaacatc aaaatttcag ttgattttgc aattgggaaa agtttaaact catccttaga
    10081 atttattctg ccttcttcta catattcgtc tatgtattca tttaattctt ctttacttat
    10141 gtacttatcc atatctacta gtaaccctaa tttatccatt tcatatgcag tatctgagta
    10201 tgctgcaaat atatttggta catcttcaga accaactttt ttatttgcag aatctaaaac
    10261 tttctctgat aaatcaacta cattaccttg actgaatgct tcaacaataa ttcctttttc
    10321 agcacctaca gtgtcattaa attccttaac aagcttatca aaagccattt tctgctgtcc
    10381 attataataa tgccaaattt gtattgatgt cggattttct gggtctaact tataattatc
    10441 ttccttcttt aaactacatc ctgtaagtaa taaaacaatc attgatgtga taattaattt
    10501 tgcaaactta cacctattca taaaatctac tccttcaaat tataaaattt ataatagcat
    10561 taaaactgta acttcactat ttatattaat tatagaacgt ttattgatat atttaaacag
    10621 gatttacaac atatttaaaa gcaattaaga aacatactat tacaaatata gaaaataaag
    10681 cttttacata atttttattt ctaaatgcac caaatgacac caatccttgt tgaatagcta
    10741 ctgtaattac taaaagtatc attattatat taagttgaac cagtttaaat aagtaaagca
    10801 atgaaaacac tactagaagt acacataata caatactaga tttattaata atatcatcaa
    10861 tcttatctac tttcttagat tgcttattaa ttttatttaa tttttcttta tttaaattct
    10921 caactttttt attatacctt tctcttgttt tatctttata tttagtattt ttatttttat
    10981 ttcccattta ttttccatcc tctataaatt ttttaattga gcttatacat tatttaaata
    11041 ttatatattt aagataccat atattcctac aaaaaggtaa cttactatgt atctattttt
    11101 gattttcgca taaaaaagcc atctccttta gaattaattc tgtattgaga cagctaattt
    11161 aactatttat cctttgaaac attttctaca ttatcatatt tactatcaac taaaactata
    11221 tcaactcttc tattttttga cctaccttct tcagatgaat tttctgctat tggtctaaac
    11281 tcaccatatc ctacagcaga taatttatct ggtgctatac ctgcattgtc aataagaagt
    11341 tgaacaacat tggttgctct cataactgat aaatcccaat ttgacttaaa ctctgaattt
    11401 tttatagaca tattgtctgt atggccttct actctcatgt aactattcat ttcatttaac
    11461 atcttaccta tttgaataat cttatctcta gaattatcct tcacaatagc tttccctgta
    11521 tcaaatagta ttgtatcttt aaggcttatt actaatcctc tatcttgaac tcttaatgat
    11581 actgaattag ccataccatt ttcgtttaaa tacttctgaa tttcttcacc aattttttta
    11641 aacttagcat tttgtaaagt atctaaatca ttacttcctg gttcaactac tggttctatc
    11701 ttgctattac caccttcaat aactccagaa gaaccaccaa aagcagaatt tagagattga
    11761 gataattgtt tatatttctc cgcatcaaca ttactcatag aatacattat tacaaagaaa
    11821 atcataagta atgttatgag gtctgaataa gttaaaagcc atcgctcatt gttttcttct
    11881 ttttcatctt catcatacaa cataaacatt ccatcctttt atattattca gctctaccac
    11941 caatttcttc aagttcaatt agttcttttg aatttaaaaa tatttttaat ttttctgtca
    12001 ttaaattaga attatcaccc tcaagtatgg ataatattgc ttctatcacc aaaagtcttt
    12061 cacttacttc ttgttgattt atagccttaa gttttgatgc tattggtaac catattaaat
    12121 tggcagaacc aacaccatac aaagtagcca agaatgcaac agaaatttga ggtcctaatg
    12181 catctggatt acttgaaaga ttacctaaaa tatgtactaa tcccataact gtacctatta
    12241 tccccagtgt aggtgcatat ccacctgctg aatcaaaaat tgctattcct tctttatgtc
    12301 gttttgatgt tatctgtatc tgtgattcca atatatttct tatagtaact gcatccactc
    12361 catctaccat aagttcaagc ccttttctaa taaaagggtc taattcatca ttctcactta
    12421 tttctttgtc aatactaaga agcccctctt tcctagcctt tgttgcaatt tctttgaaat
    12481 agattatatt ttctatgtta ttaggctttt tatttttaaa agctaataac attatcttta
    12541 tagacttttt aaacacaggg aatggagtcg aagctccaac agctcctata gttccaccaa
    12601 acacaacaag tgctgatgaa aatacaaata atgctccaac atgtccccca tcaataacaa
    12661 aagcaactac caaagatgct atccccacta tgaaaaaaat taaagttgtc atctattccc
    12721 tcctttcttt agttatacat atctaatcat ttatgacatt ataaaaagac tatctttaat
    12781 aaaaatagcc tttaataatt ggcggagaag gagggattcg aaccctcgca ccggttaccc
    12841 agcctaatcc cttagcaggg gatcctcttg agccacttga gtacttctcc atatctctat
    12901 actaataaat tatataataa aatcatattt tagtcaattg ttttataaaa tttgagttat
    12961 tttgaattat taaacatcta tttttacttt tttgcttaaa tgtaagtttt aaatatggta
    13021 aaattatctt gcataacact tataatatta tttgataaat atacatacat taacaaatat
    13081 acctaaactc tgacttaatt gtaagttatg ccaaaactaa aataatacta gtccaaggag
    13141 gatattttat gttaccacag gaaagatatg agaagatttt aagtattctc aaatcagata
    13201 atataattaa aataaatgac atagttcaaa tgtttgatat atcaatagaa actgcacgaa
    13261 gagatttagc ccatatggag agtatcggtc ttttaaaaag agtttatggt ggtgctatac
    13321 cagttatagc aagtagcgta gaacttaact atgttaaaag aaaaaaaata aactcaaacg
    13381 ataaaaaaca gattgctatt aaatgtagtg agtttataaa tacaaatgat actattttta
    13441 tggatactgg aactactgta cttgaagttt caaaaaattt gaaagataaa aagaatctaa
    13501 ctgtaataac caactcaatt ttagttgcaa acgaacttat gaatactaat ataaaagtat
    13561 atgtgcttgg gggctatctt agagaaactg aaggttcttt ttctggtccg cttacactgt
    13621 cagctattga acaatttaat gttgataaag ctattttagg cgctggaggt atcactcttg
    13681 aaaatggaat ctctgactat cacttagaag aagcacttgt tagaaaaaaa atgattgaaa
    13741 ggtctagaaa atctatagta gttgtcgaac ctcctaagtt tggtataaat tcatttgcat
    13801 cagtagctcc tatagaacat atagatacta ttattacctc tgctagtata gaccataata
    13861 taataataga gttttctcaa aaaggaatac ctttagtcat agctgataat tagcttatat
    13921 gattgatttt tagttccttg atgtaataaa ttaaaattaa ggagccaaat aattatttat
    13981 ttagctccat ttatgtctaa actatacttt atattttaat tatgtaacta ctttcagtta
    14041 gcttatcatt tttagttatt tgattgccat tttatttaat ttataagttt tagttattcg
    14101 attatttttt aattgtctgt ctttttaatt tatttttagt tatttaaact cctactttaa
    14161 aataatttaa atttgactta agtattgttt attctacact gcatctttct tcattttaat
    14221 actttgttct tcttccaagg ttaaatcttt tgtcataagt atagcaagtg caattgccaa
    14281 tactcctcca accaattttc caattacaac aggtgtaatc atctctggaa ctactcctgc
    14341 tgtaaatcct aaatggtccc ccaaagctgc tgtagcacaa accagccaag cagtatttac
    14401 tactttcccc tttggactca tatctttcat cattttatat actggaatac tattggctaa
    14461 agtaaaaact aatcctgctg cactagtggc atccatacct aattttccac ccactattgt
    14521 aagtggttta ttaagaactt taactaataa atgtaatatt ggaaaagtac ctaataacac
    14581 gattgcaata cttccaatta cttgaatacc ttctcttata ggtgtcatgc cttttataag
    14641 tactatacct gttatttctt gaaatgctgc tgctcccaaa cctatcgtta tcaatataga
    14701 tataaatttt ccaaaaatta atgacccatt tatcataaga gtagaattaa attttaaacc
    14761 tactgccaat attactgcca atattatcac tggtatcata tttataatta ccattgataa
    14821 gttaaatcct gctattaatc ctcctataat acctccaaag ggtattgtta tcaagcctat
    14881 cagtaaccct tttgcaaaga atggtctgtc ttcatattct ataagaccta gtcctactgg
    14941 aattgaaaat actaatgtac atccaagcat ggatgacaca accaatcctg caagcattcc
    15001 tgcctcttta ttgtgtgcaa gttccatagc caatggatac cctcccatat cattcgctaa
    15061 aatagttgca aacatagatg ggtcagctcc acagagattg aagattggta ttattatagg
    15121 acctagtaca tctgaaatta ctggagctaa acaaactata ccaaccattc ctaaagccaa
    15181 tggacccatt gaattaaacc cttcttcaaa ctgctcgcca agtccaaatt tatttccaat
    15241 tattctatct aacgctccta aaagcactcc cacagccatt atgtataata taattttatc
    15301 aaagggcatt tttaattcct cctatacatg taaaatactc tattgtaact taattagcac
    15361 acaccttttt ggtatcgttt tcccaattca tagctctttt tactgcttgg ttccatccaa
    15421 gtaatatttc ttctcttttt tgagtagtca tatttggaat atattttttg cttattgtaa
    15481 attcacttct aatttcatca atactgttcc agacaccaca agaaagacct gccatatatc
    15541 ctactccaag tactgtcgtc tcaggatttt ctgcaatttc aattggtata cctaatatgt
    15601 cggattgaaa ttgcattgta aagttatttt tagtaattcc accatctact ctcaacattt
    15661 ttattttttt ccctgaggct aagttcatag aatcaacaac atctttgact tgaagtgcaa
    15721 cagactcaag agtcgctctt actatatgct cttttttagt acttcctgtt atcccaacca
    15781 ttgtacctct agcatattgg tcccaataag gtgctgctat acctgcaaat gctggtacaa
    15841 aatatacacc tccagtactt gatatggaat ttgccatgtc atcagtttct gaataatttt
    15901 ttataactcc aatgccatct ctaagccatt gtattgcagc acctgctata tacactccac
    15961 catcataagc atatgtaact ttatctccta ttttccaagc aacagttgtc aaaataccat
    16021 tacctgctat atttagttcc tcacctatat tcatatatag gaaacatcct gtaccataag
    16081 tatttttaac cattcctggt tcaaaacatc cattgccaaa taaagctgct ggttggtcta
    16141 ccattgaagc agtaattttt atagaaaccc cacaaaatgc ctccttatct gtagttccaa
    16201 aatcaccact cgtaggcatt atatctgcta aaatacttct aggtactcct ataatgtcaa
    16261 gcaactctct atcccaatcc atatctctta tattaaaaag cattgttctt gctgctgtag
    16321 atacatcagt taaaaaagat tttcctcctg tcattttcca tattaaccaa ctatctaatg
    16381 ttcctgcaag tacttctcca tttttaattt tttcttttac accttttaca ttatctatta
    16441 cccatttaat ttttgtacct gagaaatatg ggtctataat taacccagtc ttatctatta
    16501 tcttattttc taaacctggt atattcttta aattttccac ataatcataa gttctcctgc
    16561 actgccacac aatagcattg taaagtggtt tacctgtatt tttatcccat aacattactg
    16621 tttcaccttg attatctata ccaattcctt ttatatcact ttcattgatt ccattttcaa
    16681 aagcctgttg taatacatta ttactcacag tttttgtatt attccaaatt tctatagggt
    16741 catgttcaac atatccagat tgtggatata tttgagtatg ttccatataa tcgctaaaaa
    16801 caaactctga tttttcgttt atcaatactg ctcttgttcc tgttgttcct tggtcaattg
    16861 ctaatacata tttcacttta aatgtcctcc tttattttca gaattaataa attctttttt
    16921 attttttgaa tatataatct attcaagtta tttatatttt atatcatcat gtggatttat
    16981 gcaatattca ttacaatatt ttttgttatt tttaattata gtgattgaaa aagtattttt
    17041 attgaaatat tgttgcaata tttattattt tattctataa tctagttaaa ataacacata
    17101 atattttaat atttacacat aatcagtcat tcaaaaattt aaatttaact ttttaaggag
    17161 gctttacaat gaaaaaaaca tatctattca gtcctggacc agtaatggtt acagataaag
    17221 tcagaaattc acttcttcac tatgatatat gccatagagg aaatgagttt atggatttat
    17281 tcaaagatac acaacaaaaa atcaataaac tatataatgc aacttctaat tactactcat
    17341 taattgtatc tggctctgga acatctgtaa atgaatgtgt actatcttct atctttgaca
    17401 aagaagatgc agttctgcta gttagtaatg gtgtttttgg agaaaggcta gaagaaatat
    17461 tatctactta taatgtaaaa acatataaac ctaattttga atgggcagaa tacccggacc
    17521 tagacatttt agaaaaatac ataattgaaa actctgatat aaaagtaatt gctatggtgt
    17581 tccatgaaac tagttcagga atgataaatc cagtccctga actaggaaaa cttgctaaga
    17641 agtataacaa aatatttttt gtagatgcaa taagtgcctc agcaggtgaa tatattgatg
    17701 tggaagagtt taatatagat ataataacag gtgttggtgg caaagctctt ggagcatttc
    17761 caggttctgc atacctttgt gctaaagaga gtattttaca aaatattaaa gaaaatcaat
    17821 gtaagaatgt gtatcttaat ctttataaac actataaagt tgctaaatca tcttctcaaa
    17881 caccaaatac acctaatgtt actttaatat ttgcccttaa tgaagcttta actgagtttt
    17941 tggaagatga cagtaaaata gaaagataca aagaatgttc tgctatttta aggtatggta
    18001 tggaagaatt gggtctaaca tttttacttc cagataagta tatgtctaat acagtaacat
    18061 ctgtatttct acctaaagaa atcaatgtaa atgagtttat attagggcta gaaagggaaa
    18121 gtggctatgt tgtctatcca ggaaaaggca aattcctaga tgctaacata ttccaagtag
    18181 caaatatggg agaaatatat ccagaagatt gttataaatt cttagatatc ttaaaatcaa
    18241 aattggagat aaaaaaagtt atataacagt ttgtttgtaa aatcctacaa tatatcagta
    18301 taaattaaat agactgattt ttttaaattt tcctataata aattatattt tatatttttg
    18361 tataagggtg aactataata tgtaaagttc acccctattt caaatctttt tccttcaata
    18421 taatcttttt cttttaattt attttatatt tttgacgcaa tcgtttttta ttcaatcatt
    18481 ttatattctt gatacaatca ttcttacact taattatttt ttgtttttga cacaatcgtt
    18541 ttttgttgaa tcattttata ttcttgatac aatcattctt acacttaatt attttttgtt
    18601 tttgacacaa tcgtttttta ttcagtcatt taatattttc aacacaatca ttcttacatt
    18661 ctattattgt ttgtttttga tacaactgtt tttattcagt catttaatat tctcaacaca
    18721 attacctttt cattcaatca aagtaatctt taagcattat ttttcaagct catcaaagta
    18781 attatatacg ataacctcac ctgtctcttt atctgtagtc tttataatgc ccttagctcc
    18841 atttacctct tcttttgtaa attcatcatc taacacaact ttgaatttat cttcctttcc
    18901 ataaccttgt tgaaattcat ctctcaaaat tgcatttttt tctgcttttg gcttcaactc
    18961 aaattcaatt ccagatttca tttcatcaaa ataatttaat actacaacct cattattcat
    19021 tttattagtt gtctttataa tccctttagc tccatttact tcttcttttg taaattcatc
    19081 atccaatgtt atattaaatt tgtcttcttt tccatattcc tcttgaaaat ccctcttcat
    19141 ttcattgtat ttagtttcaa actctttact cttgtttaat tccatagctg atacatttgt
    19201 caatgatgct ccaattgcca ttactgttaa tgccattact ataccacttt taaatttttt
    19261 tactttcata tcttacctcc taaattaaat gttctcaatg aaattatata aagaaaatcc
    19321 taagttttac agtttcattc ttgtaactaa aattactatt atgtaaccaa actttttgct
    19381 tcaactattc cttaaaagtt gcttttttga ggaatagttg aagttaaata attagatttt
    19441 atctatattt atagatttaa aatcaaattt atccatataa ataaatactt atttttgcaa
    19501 aataaaaatt tttaattact ccaatccttc ttatttactt aaaatcctat gataagaaat
    19561 ttaaaagtct ttaccttctt taacaataat ttatttactt ttaacataca aaatatagag
    19621 agtatatcaa aactatttta ctgaatattc taaaaataag taccccctat tagtatatat
    19681 atttacatat taaaaaaaag ttttaaataa agttatattt tttacaacag ttttgtaatt
    19741 aaaaacatat tgaaggtaaa tttaaaggta ctatatacta taaatatgtc gacacaataa
    19801 atttaaaaag gagaactaaa tatgaaaaaa agattaataa taatgatatt gtctgttgtc
    19861 ttagtactat caagtatact tacgatattt gcatattcaa atattaaata taataataac
    19921 aaattgatat attctaatat gatagataaa aaaactcaaa atagtgtaaa ggaaatccta
    19981 aaagaaaata aaattaatga aaaagacata gatacattta ttaaatcagt caacaattat
    20041 aataaattgc aagttaaaat acttcaaaat aatataaata tatctaaatc tggatattct
    20101 tcaatcaatg caaaacaagt tccatataac ctagaaaaat tgcaagataa ttgggtgaaa
    20161 aaattccctg attatatgga tgtaaattgt agaataactg cttttagact ttttaaagat
    20221 tttataaatt caaataagaa atttactgga gactctattg atttgaatgt cgacttggac
    20281 actataatga ataataaaga tgctaaattt agcaccaaag atgtagaaaa atttatcaac
    20341 ttcttttctg caataccagc taaagataca gatgatacaa tcaaaattgc agaacaaata
    20401 aaaaatgaat ggaaaaaaag aaaaatatct tttaaaaata ataaaaatat atctattata
    20461 aatggatttc ttcgttatcc agaaactaaa aatgtattta taggtcatac aggcatatgt
    20521 attaaaacta aaaatggcat tctattttta gaaaaatacg gtgttacatc accttatcaa
    20581 gttactaaat ttaaaaataa agaagatgta aaaaattata tgtttaatag attgaagatg
    20641 tcagaaggtg aaattgaatt acctgaccct ataataatgg aaaacgataa acttatgaaa
    20701 taataacttt aaacgcaaaa tagtatttat aattactaag tcaatataat agagaaggtc
    20761 tatagatttg tgtaaataca agcttatcta caatcttata taagaatgtt tatataaata
    20821 agatagatta attctaagtc ctattattct attgaatttt attattattt tatttagatt
    20881 ctattgttat tttacttaga acttattatt attttgttta agttctatta ctattttcaa
    20941 tcatataaat ttacaaaaga ctgtacataa atttatttta tacaaactta tctacagtct
    21001 tttgtgtgaa tatatctaaa taatatcgta tttatttatt tcctctgcac agtgagaatc
    21061 agaacctaaa actaatggaa tatcgtattt ttttaccaag tctaataagt atccatctat
    21121 ataaggctct ttgcagtact cttttctatt tccagaaaca ttataatcaa gttcataacc
    21181 tttttcttta attaacttta ttaactcttc aagaatttta tttcctttat aatcgtatgg
    21241 aaatacctga ttaaactttc taactaaatt taaatgacct attctttttg gtttatgtat
    21301 acctaaatct gaatttacag cttttatcaa tgtttcataa tacttattat aaacagcttc
    21361 aatacttcct aatttgtcga ttaaattttg aaactcctct acactgtaat ctacacaata
    21421 ataatcatca tcaatcttaa ttatatgtac tgataaaaga gaatcctcta attcctttcc
    21481 atatttattt aaattctcct ttatcccttc ttcgtatcct tctataaaat ccacttccga
    21541 cccaacattt atcttgattt taccctcata cttttctttc aacttcttga catcattaaa
    21601 atactttggt aaatcttcaa tactcataca actatcattt tcaggagcag ggtctctaaa
    21661 tccatttgca tacggaaaat gttctgtaaa tgtcatttct gttattccaa catccattgc
    21721 tctttgtaca tatttttcaa aatcatcctt acttccatga ggacaataag gtgaatgtat
    21781 atgaccatct ttcataaata attcactcct tttttaaaga aaaaatctaa tataaatgca
    21841 taaatctttt aacttcaaaa taatattttt aatcatgcta atttttatta tatctaatat
    21901 tagagtaatt ttaaactgcc ttttaagtat cttatcatta gtactatttt caacttaaca
    21961 ttaatattat tttttaactt aacattaata ctatctttaa atagtaatac tcaatatata
    22021 attacttaac ataaaataac tcaaattgct tgatgaggct tttgcagtat ttaaagaata
    22081 tataattatt taacattaaa taatccaatc ttgtaataaa atttactcat taaagtatat
    22141 tacagaaaat acctcaaaat aaacttttta gttcatgata tactcttttt tgcatgaaat
    22201 tagatatatt tttatcattt caacaatgaa agggaggctt atatccatct ttagacaacc
    22261 ccttagataa aatttttaat aattaaacat cacaaaatat aaaaatcgct tatatcaaac
    22321 gtataagcga ttaattatat ttacatatgt tttttagcct ctaacaacat tttattagct
    22381 tcttccatat actctatagc cttttcaata ctctttgctg tttcttcttt tccaatagct
    22441 ctagcctttt caacccactc tctaaatcct tcttcatgag tttcattgtg atttatccaa
    22501 tgtactaaaa gtatttttaa agttttttca tccttagact ctgatgattc ctcatgacta
    22561 tgttcgtggt cgtggtcgtg agcatggtca tgtggatgtt catgacatat atctccatga
    22621 gtatgttcgt ggcagtggtc atggtcatga tgtccatgat gatatcttac aatctcttta
    22681 tcaaaaatca ttagttattc cccctgttat tttatattaa actctttttt tataaggttt
    22741 acagaatctt ttacaagtag tgctaatggt ttaccttcta atccaactaa ctccacattt
    22801 tctggcataa taggtaaaag tatcttaagt gcctcactgt ctgcaatagc ttcacttata
    22861 ttacaagtaa cttctcccat catagaatta ggtattatta cagaaatagg tgcaactatt
    22921 atatttgctt ttttagctga tactactata gcattttccc ctgtagctcc tttattagca
    22981 tgagctttca tcatagaact agttgctata gaattagtcc ctagtgcata aatttctaca
    23041 tatgtaggta actcttctct caaagaagaa actatctggg ctccaatacc tccacccatt
    23101 ccatctatca ctgctattat catatgaaat tcccctatta attaattttc ttgtattatt
    23161 atcttatggt ccatcaatct tatttcttta attatcccat ctattatctt ttgctctcct
    23221 aataaatccg ttaaataaat ctttccatca caagggtcta tattaaccac attttccata
    23281 accttttcta actcattatt acttttacaa atgaaagctg atgattcaca catataaatc
    23341 tcctcctaat atgattttta ttaaaaatca aaaaaagatt cccttaggta tttcaataca
    23401 ccaaagaaac cttcatgatt tcagtttttg tatattatta taccttaagt atatcacttt
    23461 aatttatgta aagtcaatta aagttaacgc tttttattat actcttcatt cttgtatttt
    23521 tcatatagtt ctttaactaa ttgcttctca taatcagtca aatcgccctc cacaaactca
    23581 acattaaatt gttcagctaa tccctttact atgtttttct gtagaatatc tatgtctatt
    23641 tttctgccaa tttcattttc tattccactt gcttttttag ctgtaaattt catagctctt
    23701 tctttcaatt ctggtgtctt agtttttatt aatttaaaca atttttctac atcaaaatcc
    23761 agtattattg aaccatgttg taataaaaca ccatcttttc tactttgagc acttccaatt
    23821 accttcttat tattaatagt aacttcatat gatgcatgtg cattaaaaca tgcagctgat
    23881 aaattttccc tacttattct ctcgcctcta tttaaattat ctgtttctat accacttaga
    23941 ttcaaccctt taactagacc ttcacttata tatctataag ataggttgat gctcttatcg
    24001 attaaaggat tatcttctcc tataattata ctataggtta gctcattatc atgtaataca
    24061 gctcttccac ctgtaattct tctagtatag tctatattca tacatctaca cttatctaaa
    24121 tctatctcat cttccaattt ctgaaaatat cctatactca aacaagctgg ttcccatgta
    24181 taaaatctaa gagttggctt attatgtcct ttcttatatg cagtaaatat agcttcgtca
    24241 attgccatat tcattgctcc ttcatatgat ttattatgta taactctcca ctgattcatg
    24301 attattacgc ctccattttt agtataaata tatcctagaa atcctctata gatttatttc
    24361 tcttattgct aaatctatct cactttgatt taaaggtctt gaatagttgt atatagtact
    24421 tcctggtctt tcattatagt atggtctatt acaatcctta caacctctta tttcaaaagg
    24481 atagcctttg tttatgtctt ttaaaatatc attgtcaagc tttatactat ttaagtatcc
    24541 atttttaaac ttaaaatact cttttggata acctttattt atcatataag acattaactg
    24601 tacccttcta taactttcta tgcttggttg atttatcttt tccattttag ttcctctaac
    24661 tggagtaaat gcaaataaac taatcgttac atcattttcc tttaaataag tatataaatt
    24721 gtatatatct tcatgacttt cacccatacc aactattata tgtgtactta ttttattggg
    24781 atatgatttt gacatttcag ttataaattt taacttttca tcatagttat ttccttttat
    24841 tttttcatat agttctttat ttgctgcatc tattgctatt cctattttat caactcctgc
    24901 tgaaaaaaac ttctttatct gttcatcatt ttctaatttt gcagatagtg aaattggcat
    24961 gtctatctta ccacttatat agtttataaa gtctaaaaca gagttatgtg cttcttcact
    25021 tgccattgat tgaatacata ttctctttat attttttcct ttataagctt ttaaagcatc
    25081 taatatttct tcttttgaaa actctggcca aattactctt gataatttat cttttctagt
    25141 actactttct attgattgag aacaaaaact gcatttattt atgcattttt ctccaatcat
    25201 tatatatgct gtggtaggag gtatatcgct ttttttgttt aatatcccaa gttctattgc
    25261 tgtcccaact gatagtctaa tcataaaacg caacactcct tacactcatt tattgtcata
    25321 ttcatttcta tagccttatt ctttgcagac cttgatggta atactattct attgactcca
    25381 cacattatag ataattggtc tagctctttt ctatacactc ctcttggtct catacaacct
    25441 agattaattt cagtatctgg taaattaatt ctagcttcac ataaaatatc tgctacccct
    25501 tctaactcag gaggttctac attttcatac tcagtccctt ttgttggaat aaggactata
    25561 aatgtaagct tattaggagg atttttttgt aggtattcta taatttcata ttcacccttt
    25621 atttgtcctc cttttaaacc aatacatata tgtggtgcta cttctgtatg ttcttgtatt
    25681 gtattataga cttcaatata atcttcttta ctctttttca tcttataaac ttctcttatt
    25741 gtctcatcat caaacactaa atcaaaagaa actatatcta aatacttaca caactctaca
    25801 atgctatctt tatccataag acctaaatga gcattcaatc tatatccttg ctcttttaag
    25861 tttttaatgg tattaatatg agtatttata gggacatctc cctcataact acaaccgcca
    25921 ctcaatagaa agctagttat attccttgat tgtacttttt cctcatattc ttctattggc
    25981 accatattgt ttaagtagtg accgttgcaa tgggcacatt tcaaactaca ttgattgctt
    26041 gtagtactaa gagctagtgt ctggttagga taagcaaact ctattttatt tccaaaattc
    26101 tttaatttaa tatcaaatgc tattttcatt ttttcagata gattcttatt catagtttat
    26161 tccttcttaa gtacatttta ctcttctagt aatttctttg ctgttgggaa ctgctctata
    26221 ttcgtatgtg gtaagaaaca tgcagaaata aattcatcca tataacttgg atatacacta
    26281 agttcaacat aagttatttg attacctatt tcttcaagtt tattttttgc atctttactt
    26341 ataagcgcta agtaagaacc aacaagtgaa ctattcccta tataagtaaa tttttctcta
    26401 tcaatatcag gaagtaaccc tataattatt gagttttcta tgtctaggtt gtttcctata
    26461 ccacctgcta tataaaccct atctaatata ctaaaatcca tacctaaact atctacaaga
    26521 gtgtatgcgc ctgaatatat agctccttta gctctgatga aattatctat atcaacttca
    26581 ttgactacta tatcattttc taaatcaaat tcttctttaa atgctaatac atactctcct
    26641 atctcatgct cattaaatct aactctctta ttatctaaat ccctgtatat tttacctctt
    26701 ctatctatta cacctttagt aatcatttga cagattaaat caattatacc agaaccacat
    26761 ataccaactg gtgcacattc atcaataatc tttaatgttg gctctaaagt atctttatca
    26821 ataattactt tctctattgc tcctgctgat gctctcattc cacagcttat ccctccacct
    26881 tcaaaagcag gtcctgctga acatgcacag ctcatcatat aatctttatt tccaaataca
    26941 atctctccat tagttcctaa atctataaat aaaacatttt cttcacttga ccatatccct
    27001 gctgataata cacctgctgt tatatctcct cctacataac ttgcaacaga tggagctaag
    27061 tacacatatg cactgtcatt tacaaaaaga ccaacatttt cacccataag ttttggagat
    27121 tttaaaaatg gtggtatgta aggttcttgt cttaagaagt ctgtatacac acccaagaat
    27181 aaacttgtca tagttgtatt tccggcagcc actaatgtaa ctacatcttc cttatctatt
    27241 ccatttcttt catatattgt ttttaatagt ggatttatag tttcctcaac tatagcttta
    27301 tgaagtgtct ctaatccatt tttcttagtt gaatatataa ttctatttat aacatctgct
    27361 ccatatttta tctgtgcatt tccagaagat gctttatcta ctacctcttt tgagtatagg
    27421 tctactaaac aaacaactac tgaagttgta ccaatatcta ttgcaactcc gtataaggaa
    27481 ttttctttat ttccttgttc tatatttatg attgtaagtt tcttttgttt ttgaacatat
    27541 gttattgtaa ccttaaaatc actctttcta aatacagttg gcatttttct aagtatatcc
    27601 aatctaaaat ctatttcatt atatcctagg ttatttctaa catatctttc caatctatct
    27661 acatcactta tattatcatc taaatttggt tcttccattt ctatgtattt cttttttata
    27721 tttgttttaa attgaaggtt atgttcttca attatttttt tagctctttc aaaaatttcc
    27781 ctatcctctt ttttattact accttctatc ttcataccat gcatagaaga tgatacttta
    27841 gaaggaactt caatttctat atctgatatt acctttgtac aacaagctag tatataacct
    27901 tgctcccact catcatctgt tatatgtctt gttttttctg tatcaacttt tccattcaat
    27961 aattttactt tacacttccc acaagacacg tttccattac aaggagcatc tatgaatata
    28021 tctgcatttc ttgcaacctc tagtaatata tccccctcat tacaataaac ctctttattg
    28081 tttggtgtaa aacttacttt tatcatgtta tccctcccaa tttgttctat atatgataaa
    28141 aggaaagtat agctaaattt gcgtgcactc aaattttact atactttccc caattataat
    28201 aatatcttaa tctttaatta ttctaatcca gcctcgtatt ctttatcact taataacgta
    28261 tcaagttcag ccacatcagc tagttttact tttaatatcc agttttcata tgggtcttca
    28321 tttatacatt ctggctcatc ttctaatttt tcattaactt ccaatacctc accattaaca
    28381 ggagatatta aatcagaagc tactttagaa gactcaacta ctccaaaatc tactccctta
    28441 gttacagtat cttctacttc tggtgtttca acaaacaata tttctcctaa ttgatcttga
    28501 gcatagtctg ttatacctat atatacaaca tctccatcaa ttacttttac ccactcatga
    28561 tctttagagt attttaattc tggtaataat ttcatttcga tagaccccca atattatatt
    28621 attgattaaa ttacttaaat catattaata ttatatcata ttattttaaa ttttccatca
    28681 attacattac actttccata gctaatgctg gatgaccttt ttcttctaag aaagctaata
    28741 ctccttcaga atcgtcagct atagtttcat cacaaaccat atcacagaag ttttctattc
    28801 cagtcatttc tttaactgta gcatttaatt tatcagctac ataatctttt aattcttttg
    28861 gcatccaaac tattctttct ggtccacctt ctgcataagc gaatttttta gaagatataa
    28921 aatgtcttcc gtgtcccata aatcctggag tttgaactcc tccacctgtc atagaagcaa
    28981 gttctccgaa agtcatacca actggagtaa cacttgcaaa ttctctgtta actacaacaa
    29041 atccatttgc ttctggcatt ataccacaga tacattcgaa gcatccacaa gaagtcattg
    29101 ggtcttctag tatagagtat aatgtaacag attcaactgc accttgagat atttggttta
    29161 cagtttcatt tactgaattc catacacctg ttctatcatc taagcactcg cctttttcta
    29221 ttggttgaca aggacctgtt gggtctaatt ctttagtagc cttagcatct aaccagctaa
    29281 ctgctccaca aagaccaagt ctttcaggag taacaacaca aacgtgagct ggtgcaaatg
    29341 attgacataa gttacaagaa tagaaagtat caacactttc atcaactaat gaagctaatc
    29401 tttcatctct agcattgtac ttagctattg cttctccttt taattcagaa actttttcag
    29461 catctgtaat tatagttatt tcacacttat caactactga ttcaaattca tctaacatct
    29521 tagcatataa aacttctcct atatgctcaa gtctaaatcc tttatcaaat gcatctttag
    29581 agattcttac ccaagccata tctctttgtc caacgtgcat tacaccttct atatagttta
    29641 agaagtagtg gaaacgtctt tcaagaactg gctcgaaatc ttcttgcata tttttaccag
    29701 ctattttaac tattacagca agtggtaatc ttaatacacc atctgcatca acttcatcta
    29761 tatttggccc tattatttct atcttatggt cttcaacttc tgttgcttct ttcttaacaa
    29821 caagctccca agcttcagtt ctgtttccac caaactcagc aaacatatcg ctctttctaa
    29881 ttctctcacc ttcaaatgct gctgcaaatg aaactgggat aggtatttca gtaactttta
    29941 tttttattcc tctagcttct aatgaagtag ctactatctt atcgtaatct ttttgagtta
    30001 ataggttcat tggaacttca agaactgttt ggtcagttat aactgggaat cctaaagcta
    30061 ttgctccagc acctgcagat acaactaatt cacttaatgg tccaaatgca ttaacaaatg
    30121 caggaactct attagctgtg tactctaata atccgtttaa atcaccagga gttaatccac
    30181 cgaatattaa tgctgctctt actgcaacag atacaacgtg tataacagaa gttacatcat
    30241 atcctagagg tataactctt agctcaagac ccatttttac tccagcttct atagcttggt
    30301 ctataacttt accaactaag aaagttagta aacctttaga ttggtaatct tttataactt
    30361 ttgctgctga ttctgcatct ggacactcac caagaacaac tgcaacacca ggtatatctc
    30421 ctgtaactaa tggtacacca agtgatctga ttatagggtc agttatatga cctgcacatg
    30481 gctcactata tggagcatcc atagttgaat attttaatgc ttcaattact tctgctgcta
    30541 aagctgtagc taaaccagca ttaaaagcat gttctagtaa atgagttcta tttattaaag
    30601 attttactac ttctaaagca ccttctaagt cccctaaagt gttcatcttt tgtcctgttg
    30661 cagcatatat acaaggtaat gaatatgctg tatcagggaa agcaacttta tgctcttttc
    30721 cattcttttc tatagcttca gctaacatag cttgagccgc acctaaagct tgttctgacc
    30781 ctgtaaagat tatattatat agattcattc tatttccccc tttaatattt acacctattt
    30841 tttattaact ataccctaaa aaccctagaa agcaaatcca ccttcattta actctaagaa
    30901 agagtctgca tataaagatg ccccgttgat tatgtcacaa gattttacag ttttcattaa
    30961 ttctgggtca catggattca ttatagctga actaaatcca ttagccattg ccattgctaa
    31021 gaatgcacta tctaaaacag gtctaacatg cttaggacat ccattagata cgttagataa
    31081 tcctcctgta gttaaaagtc ccatctcagt catcattttt atagcttcta aaacttctac
    31141 ttgtttttct tgcatacctt ttataactaa gcataatggg tcaaatagta tatcagttgg
    31201 ctccattcct aacattaagc ctttttctaa tatttcttgg cagtaagcca tacgctcatc
    31261 attatctctt gggatacctt cttttgcaca taaacctata accattgctt cgtattcagc
    31321 tgctatatct attaaatcaa atcttgagcc agcatcagca gagtttatta ttggttttgc
    31381 attagttcta tcataaactt taagtccagc ttcgatagct tttttattag ctgtatctaa
    31441 tgctatagga acattgttga actcagattg aagtaatttg attccccatg tcattatttc
    31501 ttcgccatct ctttcggcag gtcctatatt aaaatctata tagtgtgctc ctgcttctaa
    31561 ttgctctttt gctcttttta agattggagc tgggtctctt tctgctaatg cttttcttat
    31621 tgaaggtgat atacaatgta ttctctcacc tataatcata aatttttcca tttataatgt
    31681 ccccctttaa atttaatatt aatagttagt taatatttta ttagtttgtt tggcatgctt
    31741 tttcttggta tccttttaag aacttaggta attccataga ttcctctggt cctataacta
    31801 cattccatcc tggtaagtta tcttctatat cacctttaag tactgcaact tttcctggaa
    31861 tgataaggtc tttacaatta gttacttctt ctaccttact ttctttaatg aaagcagaga
    31921 ttgagtttcc accaaattta ccagcagccc aagatgtaag aactgaatat ccacctgcat
    31981 ctggtattac taaccatact ggaacttttg atctttctat atcaccagca actatgaagt
    32041 aagttaatgc aaagtcaaca gtaactaata ctggagaatt ttcatctgga ttgttgattg
    32101 gataaatctt tggttcaact ctcattggtc tttgtgggtc agtgtatatg ttttgtctta
    32161 gtgcaaataa tggtaatgcc ttagcataac taatatcatc tattactatt atagaaccgt
    32221 attttatagt gaatattgat gataaagcaa cttccatcat agggtttgaa ttagataatc
    32281 tatttgcaaa tactattgaa ggatatccaa atgttctatc ttgctctttt aaagctgttc
    32341 ttctaacttg tatagcatta gtgtaagtat cttttatgtt ttctcctgtt acatctaata
    32401 ctaattcttt atatccagcg gcttgaatta attcaactgt ttcatataat tcttctaagc
    32461 taccagcttt tacacctaat ggtaaacttg ctcctttaac tacttctatc atatctttgt
    32521 agttctcttt agttgctcca tataccattg gtctagcatc ttttaatact tcaacagctt
    32581 ctttaactac ttgtgcatca tcacaagcta aaatataagc tacttctaat ccactgcctt
    32641 ttattttatc tattaatttt aaatacgcat ctttatctcc acaatactct aaaacagcca
    32701 tttcaacttt catttgttca ccaattctta catagtcaac ttttttcatg ttagctattt
    32761 tagcatctac tgcttcatca ctcatacaag tacagaatga aactgcatat ctatttctac
    32821 ttactaatgt tttttcatgt ctaaataata ctgtttctcc acctagttca tactcagatg
    32881 caccagcacc aacttttaaa gctttcatta aaggtgcagt agcctctgat aattttgcta
    32941 tagcgtcatc agacatatgt gggcatttac ctacttctac agctcctgaa gcaaccttca
    33001 tagagaaagc catacaagtt gggaatccac aatccttaca gtttttcttt ggtgttaatt
    33061 taaatatatc taaagctttt aatgccatta ttttttcccc ctaaccttaa caatttaatt
    33121 aagctaatgc gttaaccaat tcttttatag tttctattga ttttggatga cgaagtataa
    33181 ctgcgtttga accacctact aaaacacttg ctgcagttga aacttccatt gctatagttc
    33241 tttcttctgg acaaccccaa tctggctcat cttctattgg agctatagct tctttaacat
    33301 gacctacttc aaaagctact ggtgttatga taggcatttg taatgtctta tcattttgac
    33361 caaatgctgc aagtctaatt ctatccatag tagatgcaac gtactcatat ccataaccaa
    33421 ctgctgaaca tccaacattc ataactatat tttcaccttt aacgcctagt tgagttaaca
    33481 atacgtttaa ttgtttagct aggtttatat caacagaaga ttcagctcct actttatgtg
    33541 cataagccat accagctgat gctcctactc ctttgtagtt atcttctact gctgacataa
    33601 ataagcagtt atgtccatcc aatgtttgag ctaatttttc aaataattta ccatcttttt
    33661 catgatttcc tgaaccagct acaactaaag gtaattttat tgcttcaatt actgccttag
    33721 ctacatcagc acattcatca actgacttat ctaatccatt tgggtcagaa ccatcaaatt
    33781 ttaaacaaat aaaatctgct tgtgtattag cttcaacata tttagcccac tctactggac
    33841 aattagctac atctttgtat aattccttat atgaatcagt ccagctttca ggataaacgt
    33901 ctgatatttg tatacctatt tttggagaat tacctacttc tccatcaaaa ctataaaaag
    33961 gtaatacatt ttccccacct aatttaattg ctttttcccc tattcctact tcaacttctg
    34021 atatttttcc agaatatttt tgagtagaca ttttaaatgc catatttttt tcccccttaa
    34081 gcctatttta attctaattt agcaaaaatt tctttcatag ccactttaga ttttgaatct
    34141 tcaggtaaat taactaaagg aatacctgta gaatcatatt catatatcaa ttcatccata
    34201 ggtacaacac cgattagctc taggttatgc ttttcaattt cttctttaac accatcattc
    34261 ataaccccat ttggaacttt atttacaatc aaaagtattc ttccaacact taactttagt
    34321 tcctcagcta aatctcttat tctagcaaca gcttgtatgc tacgtcttga gcaatcacta
    34381 accaataaaa gtgtatcaac atgtctagtg acttttctac ttagatgttc cataccagct
    34441 tcgttgtcca tgactaagta tttgtaatga ccagatattt tgtttacttg ttctctaagt
    34501 atcccattta caaaacagta acatccttca ccttctgacc tacccattac taataagtca
    34561 tatccttcgc cttcttcgat tatagaattt aatctaaatt gaagatattg tgcctttgtc
    34621 ataccaccag ggaatgcatt gcctaacttt tctctttgat ttacttcttc tcttatttct
    34681 cctattgttg cttcaacttc gatacctaac acttcattta tgttagcatt ggcatcagca
    34741 tctacaacta atactggtcc ctttttgtcc ttaaccaaat aatcaatcaa aagccctgtg
    34801 agacttgttt taccagttcc accttttcct gcaacagcta tattgtatcc cattttaaga
    34861 cttccccctt aaatctagcc acagagcctt atgtactctg tctgtctatt ataatttagg
    34921 tacagaatga acacattctc catgtacatc atgaagtgct tccattagcc cttcagataa
    34981 acttggatgt ggatgtattg catcccctac ttgttctact gttaatccta gatgaacagc
    35041 aagtgacaac tctgtcaata aatctgtagc atgaggtcct actactgctg cacctattat
    35101 cttatcagtt tctttgtcag ctataacttt tacaaatcct tggaaatgtc ctatagcttg
    35161 tgcttttcca agacctctaa aatcaaattg acctacattg tattctacac cttcagcttc
    35221 aagttgcttt tcagtcttac caacaccagc aacttcaggt tcagtataaa cacatcttgg
    35281 aattgctcta taatctacta ccttagtctt acctaaagca ttttcaactg ctacgatacc
    35341 ttctttagaa gcaacatgtg ctaggaaagg agtatctatt atatcgccta ttgcgtatat
    35401 accttctaca ttagtttcaa gatgttcatt aactactact tttcctcttt ccatttcaat
    35461 tcctatatct tctactccag aattgtcaag gttaggtctt ctaccaacac atactaatgc
    35521 atattgtgct tctataacct ttccattaga aagagttgca acagccttac catcaactac
    35581 ttcacaagtt tgtactccaa tacctgtaat aaccttaatt ttatctttct taaattgtct
    35641 aagtagttgt ttagctacat ctttgtcttc atttaatagt atttggtcaa ccatctcaac
    35701 tatagttact tctgttccta aggctctaaa gaactgccct atctcacatc ctataactcc
    35761 accacctact attaacatag actcaggtat ctcttcaagt ccaagaactt catcactagt
    35821 tattacaact tttccatcat atgggaacat tcttggtaca actggaacag aaccatttgc
    35881 tagtattatc ttatctgctt ttatagtttc tactgttcca tcatctttag ttacttctat
    35941 agtgttttta tcaattaatt ttccaaaacc attaactaag tttactcctc ttttttcaaa
    36001 taagaactct ataccactta ttaattggtt tacaacttta ttttttcttt ccattatggc
    36061 agtgaagttt ggcttaattg taccatctat ttctatacca aaatcctttg cttcttttac
    36121 agtattcaat actcctgaag aagcaagaag tgctttagtt ggtatacatc ctgcatttaa
    36181 gcaagttcct ccaactcttc ttttttcaac aactgttaca tctgcaccaa gcatagaagc
    36241 ttttatagct gctacatatc ctcctggtcc accacctact actactatct tcatctttaa
    36301 ttcccccaaa cctaatataa tctacaatct tgcaatacta taaacctgcg gcatccagta
    36361 tagcaggtat attctcttct gccccaattg ccattatatg aacaccatca cataaatctt
    36421 cttcttttaa ttgtttgata agttcccctg ccatttttat tccttcactt acccagtttt
    36481 cttttccagc tgctcttaat ctttcgattt gttcatctgg aacaaatatt cctggtacat
    36541 ttgcagtcat aaatttagcc attcctggtg attttaaagg tactattcct gctaatacct
    36601 tgcaatccat atcccttgtt aattctctaa actttctcat tgtatttatg tcataaagtg
    36661 cttgtgtttg gaaaaattta gcccctgctt ttattttctt tttcattttt aataattgaa
    36721 cttctattgg agaatattct ggagttactg atgctcctag ataaaaatct ggagaacctt
    36781 ttaacttatt accagccatg tccgtacctg ccattaaagt ctcagcagtt tgaagtatcc
    36841 ccacagaatc taaatcaaac actcccttag cttgtggatg gtctcctacg ctagtatggt
    36901 ctcctgttag tgccaacaga ttgtttatcc caaatacacc tgctgacaac atttctcctt
    36961 gtatagctat tctatttcta tctctccctg ttatttgaat aactggctct aatccagcat
    37021 cttttaataa tttacatgta gcaagagaag ttgctctcat aactgccgat tgaaagtctg
    37081 ttacatttgc tgcatgaact cttccaacta acggctttgc acattctatt aaatgtgaaa
    37141 ggtcagtccc ttttggagga gccatttcag tagtaactgc aaattttcca ctttctaatg
    37201 tttctcttaa taagctcatc tctaatcccc cttttaacct tctaaaaaaa cttttatgaa
    37261 tttgctgctg cttctttctt tttctttgca cttaaacttc ttggattatt ttgcttagaa
    37321 tagtcttttg gtggtcttat ttctgctaag ttatctaatt gtcctatagc ttctagtctt
    37381 tcatatatct ttatccaagc acaatcattc tctgagttta cttcacactt accattttta
    37441 gctccaccac aagccccatt cataagacct ttagcacaca tagttactgg acatatccca
    37501 cctgtccaac caagttcaca gtctccacaa gccttacagg cttcttcata ttctccaact
    37561 ctttgtactt cccctataaa caaagtattg ttggctggat aaactggctt atcttttaaa
    37621 ttcttaacta ttgtctgtgt accatctcca catgctaaag ataaaactgc atcagcttcc
    37681 ttagtctctt cttttagagc ctttaaatcc tttttagact ttaaaaggtt acaagcaggg
    37741 tcaagcatta catatcctaa gatttttttg ccttcacctt caagagtttc cttcattttt
    37801 aaaacttctt cttccccacc acttttacaa gttgctgcac attgattaca accaactaaa
    37861 accagcttgt caaaatcttt taagtaccct agcacttctt ctaatggttt attttcagaa
    37921 attatcatat ctacttcccc cctaaacctt ccacatatat atatctattt attgttttgt
    37981 aatttgcaag ccttaactac atgttttgca agtatagatg ttgtaactga accaaccccc
    38041 gctggaactg gagttatcat tgatactttg tctaaaactg catttgtatc aacatctcca
    38101 cataaatttc cttcttcatc aacatttata ccaacgtcta taactaccgc tccatcttta
    38161 acaaaacttt catcaaccat cttagctcta ccaatagctg ctattagcac gtctgcctct
    38221 gctgctacac ctgatagatt tttagttttt gaatgacata ttgtaacagt tgcgtgttca
    38281 cttaataaaa gcattgatac tggctttcca actaccattg atcttccaag aactgttacc
    38341 ttacttcctt ttaaatcaac attatagtgt tttaatatct caactactgc tgtaggtgta
    38401 catggtggaa atccactttt atccccttcc attaccttag cagagtttat tggactaaaa
    38461 caatctacgt ctttttccgg tgcaataaca tattttataa cttcttcatt taagtgtttt
    38521 ggaagaggtc taaaacataa tataccatta acatttttgt catcattaac tctctttaat
    38581 acatcaatat attcctcttg tgttatatcc tcagctaact ctaacacttc tgttgttata
    38641 cctatgtttt gacatctctt tagtgctcct ctttcataag ataaatcatc acttcttgcc
    38701 ccaactctaa ctattgttag tttaggattt ataccttctt taattagtaa atcgacttct
    38761 tttattaatt cttcactaat cttatcagct acaggttttc cttttataat ttgtccttta
    38821 gttgacattc cttccataca ttcacaactc ccctacaagc aaacttaaat taatttattc
    38881 tatataccac atattaataa catagtatct actttcgtca tttaaaaatt attttccaag
    38941 agctttttca actttggcat aaacttcatc acaaattttt acaccatctt caactaactt
    39001 atctacttct gtttttacct tattaacata ttctttatct tgtatagaat ttatatttat
    39061 aactacattt aattgtccac caagtatagc agctcttaaa cactgaactc ctacaccaac
    39121 atcacttata gcaagtcttg aacctttatc aactaaatct tcatgtaact taatagcttc
    39181 atagcaaact cttactatgt ttaatggtac ttcacaagca acttttaatg ccttttccat
    39241 tgtttctgct tttattcttt tttcttcttc tgtttcttta ggaagcccgt aagcttttga
    39301 taatggtaag aaacattctg catcatcatc tatcattttt aataaatctt tttctaactt
    39361 tcctgcctta cttaatatct cttttacact ttcttcatac tcagcatact tcttcttccc
    39421 tattgtaagg ttacatacca tactacctaa agccatacct attgcaccta ctagtgcagc
    39481 agctccccca ccacctggta ctgcttcttt ggaagatagt acttctacaa aatcaacaca
    39541 agttttatct gctattttca tgataatcct ccttgaaagg atgtaggaaa atatctcaaa
    39601 ttgttcgaga tattttacga actattttaa gatatctcct actctttatt tataaattaa
    39661 tttccttaga ataatccagc tattactcca ttttcatcaa catctatttt ttctgctgct
    39721 ggaacttttg gtaatcctgg catcttcatt atttctccag taagtgcaac tataaatcca
    39781 gctcctgctg aaattgttgc ttgtcttaca gttattctaa atcctgttgg tctacctaat
    39841 ttagtttggt catcagttaa agaatattga gtcttagcca tacatactgg aactttagta
    39901 aatccaagtt tttctaagtt agctatttcc ttatcagctt caggagtata atctacacca
    39961 tctgctccat aaatcttagt agctatagca tttatcttgt cttttataga taaatcatct
    40021 tcatagcaga atctaaagtt attttcttct tcatccaata atcttaaaac ttctttagct
    40081 actgcaattc caccttctcc accttttgcc catacttcag aaagagcaac attaacacct
    40141 aattccttac acttgtcttc aacaagttta agttcagctt cagtatcaag tgggaatctg
    40201 ttgattgcaa caactgctgg taatccatat acttgagtta tgttttcaac atgttttaat
    40261 aagtttggaa gtcctttttc aagagcttct aggttttcgt tatttaagtc tgctttagca
    40321 actccaccat tgtattttaa tgctcttaca gtagcaacta ttataacagc atctggtttt
    40381 aagtttgcca ttctacattt tatatctaag aatttttctg ctccaaggtc agcaccgaaa
    40441 ccagcctcag ttattacata atctgcaaag tgcatagcca ttcttgtagc tataacagag
    40501 ttacatccat gagctatatt tgcgaatggt ccaccgtgta caaatgatgg tgttccttca
    40561 agagtttgaa ctaggtttgg ttttaaagca tcttttaata atgcagccat agcaccatta
    40621 gcttttaatt gtctagctgt tacaggttca ccttcgtagc tgtatccaac tattatgttt
    40681 cctaatcttt cttttaaatc agatatatca cttgccaaac agaacgctgc cattatttca
    40741 gaagcaacag ttatatcgaa tccatcttgt ctaactgctc catcaccttt tttacccata
    40801 ccatcaacga tatttctaag ttgtctatcg ttcatgtcta cacatcttct ccaagttatt
    40861 ttcttagggt ctattctaag tgcatttcct tggtgaatat ggttatcaag catagcagct
    40921 aaaagattgt tagcagctcc tatagcgtga aaatctcctg tgaagtgtaa gtttatatct
    40981 tccataggaa caacttgtgc atatcctcca ccagctgctc cacctttaac accaaatact
    41041 ggtcctagag atggttctct taaagcaact aatacatttt tgtctagttt agcaaatgca
    41101 tcagcaacac ctatagtagt agtagttttt ccttcacctg ctggagttgg gtttatagct
    41161 gtagttagta ttaacttagc ttttttacca gtctctcttt ttagtagatt gtagtcaact
    41221 tttgctttgt atttaccata aagttctaca tcatcttcac ctagtcctaa tttttttgca
    41281 acctctctaa tatcttgagg cttagcttct tgagctattt caatgtcaga tttaaatccc
    41341 ataactgaat ctcctcccac aacctaaata gatttaaaat ataatttttg taaaaattgt
    41401 attaatatgt aaaaattata ttttataaga taattataca tgtaaaatta cttaaaaact
    41461 agctactaag ctattaaaat attcaaactt aatagctagt tatttatcta attacttact
    41521 tattacctat ctattgccta tgtctaacct ttaaccaact taaaatccca aatcaaaatt
    41581 tctatctatt ttatttatcc ttaagtgaca ttaatttatc ttttattgct ttaatctgtt
    41641 ctttcgttgt ttcactagaa tcatatggag attgattagc tctatcagaa tcaataacat
    41701 cttggttata ataaataaat cctaaagatt ctccatcttc taagttttgg attataaatt
    41761 cttcatcttc cttatttcta attttatttc ctactacaaa tactttattt acacctatat
    41821 catgtccaag tttcttaact tttctataag tctgtagact tctctctcct ggttctacaa
    41881 ctactataaa agcatctaca ccttgggctg ttcctcttcc taagtgttca attcccgctt
    41941 ccatatccat aaccactaca tctttatttt gtagtattaa atgtgagcag agtctcttca
    42001 aaagaacatg ctctggacat acacatccag taccaccaga atctacggtt cccaatgtaa
    42061 gtaatcttac tccattgtat tctttacaga aattttcagg gatatcgtct actttaggat
    42121 tcatcttaaa catttttcca aatgaaccta cagaagcagc tgttctatct gaaactaatt
    42181 ttttcatttc tgatataggt actattgatt catatacttc ttttggaaaa cctagtgcta
    42241 aagctaaatt agcatcaggg tcggcatcaa cagcaacaac tctgtatccg tcttcagcaa
    42301 acatcctaga gagcattgaa gaaaaagtcg ttttacctac tccaccttta cctgttattg
    42361 ctatcttcat aatccctacc accttttatt actatttgct ttttagtagt taattttaca
    42421 gttaaatatt ttttatactc tatattttta tacactaaaa ataaactaca gctagtcctt
    42481 acaggaacca attaaattta ccctactagc ttttcaaagc agcatgtata gttttattat
    42541 tctttaatat tgtttatatt ttatttattc agtatattca ttatattttg atgttcttta
    42601 ctttaatatt tgactttatt caactttatt caaccagaaa cttcttataa aaacgtttat
    42661 tctataactt cactattttt taagcttcag ccttttctgc catcttttct tcaactaatg
    42721 cttcaaagtg aacacgtttt ttctctatat cttctattat tgtagctgct aactcttttg
    42781 gatttgtatt tacagtaaat gtagctccaa ctttatcttt taattcacta gttaatatat
    42841 ccactgctct tgaagaacca gctattggag gcattattcc taaataagtg tctataccag
    42901 aagctacaac atagcatcct atagcaactg ctttttctga catccactct ggagctatac
    42961 ctacaactgg aaggtcacac atatccatat ctaagtaatt agctgctgct ccaactaaat
    43021 ctagtatacg acttatatca acacaagaac ccatatgtag tactggtggg attcctacta
    43081 atttacagac agttgcaaga cctttacctg catatttttc agccgcatca gattccatta
    43141 aaccaaactt agctgctgct gaagctccac aacctgtagt aactactatt atgtcgtttt
    43201 tgattaattc tttcattatt gttacgtgag cctcatttga aactccttta gcattgttac
    43261 atccaactac accagctgct cctcttaata ctccagattt taaacagtct gttaatggct
    43321 taactgttcc tgctgggtct atatgagagt ttacaactct gtctaattga tttactactg
    43381 cttctacact atacccaact gttgcgcctg attttaattc aggtataagt acttttgatt
    43441 tatctctatt tttaaagttt aaaatagctt ctttaactat tgctttagca tcatcaagtg
    43501 cttgttcttc tctaaattca atataagttg aacctgttat cttagctttt ggagaagttg
    43561 ttacaaattt agtatggtaa caatctgcaa ctctagctaa tgcagggaat atacattgaa
    43621 cgtcaactat tacagcttca actgctccag ttattattgc aagttcttgt tgatggaagt
    43681 ctcctgctat ttttacacca tgtctcattg taatctcatt acctgtacaa cacatacctg
    43741 ctaagtttat tccatcagca ccaacttctt tagctaaagc tactaagtct ggctcttctg
    43801 atgctaaaac tatcatttct gataatgctg gctcatgtcc atgtaatatt atgttaactt
    43861 tattttcttc taatactgct aaattcgcct ctgttcttct tggcactgga gttccaaata
    43921 agatatcgct tagacgagta cctatcatag aaccacccca accatcagcc atagaagttc
    43981 taagactcat gtgtattaaa ctatctatat caccagtaca tcctatatga gtagagtgca
    44041 ttattgttgc aatttctcta tctatagctc ttggctctat agcgtattct ttccatattt
    44101 tttgtcttgg ttctggtgca ttttttataa atcttaatgt cccaaaaggt tttccaaatt
    44161 ccattaatgc aatttctgcc acttcatgtg ctacatcata gatatctcta ccttctgtct
    44221 ctacatccca ttctttagct aaagtaatta acttagcttc gtctcttatt ttatagtttc
    44281 catttggatc agctaatgct aatgtatgtg ctatatctct agcatggtct gaatgggcag
    44341 ctgtcccacc agcaaccatt cttgcaaagt ttctacctac tatagtatgc tcatctgctc
    44401 cacataaccc ccttggagtc ttagggctta ttctacatgg tcccattcca catattctac
    44461 agcaaacacc ttgaagacca aaaccacatt gtgccttaaa gccttctttt ctatcataca
    44521 ttgtttctac gccttcttct ctagctttag ctatcatctt ctggctgttt aaatcaattg
    44581 ttaacatttt ttcatccata ttcctatccc ctttttttga tttttaaaat cccccaggtg
    44641 actgacttca tgtcataaaa taataaaata aatgctttct aagttgatta tatactaatt
    44701 ttcagtgctt tgctttagat ttaaatattt ttttaacaaa attagataat acataaaaat
    44761 tttattttct acacttaatt taagttgatt ttatcgcttg tttttggcta tttgttaata
    44821 tctaaaccta cttttttgat acttcagttt aattaaatta tgttttgatt tttttaaatc
    44881 aaatttgaaa tttttctagt catttttata ttattgcaga ttgtttgtgt atttattatc
    44941 tttcactact gtttggactt attacagatt tttactccct aaacttaatt agtaaaaact
    45001 tcttagaata gcattttttg gactaatttt tttgaatttt tttatttttc ctactttaat
    45061 attaattata gcttcaaatt gaacatttgt atatattcat ttgaagctat aattattttt
    45121 tatataaaac ttttttaata cagcattaat ttagacattt tgactatttt ttctacttta
    45181 attcatttat ttcaagcgat ttatcctatt tcatattttt agctacaata gccccatatg
    45241 caatagaata taatttagat tcatgtgaat cagctcttga cactaaaact ataggagctt
    45301 ttgcacccat aattatacct gctgatttag agtctgccat atatgtaaag gctttcccta
    45361 ttccattacc aacctctatt gttggaacca atatgatatc tacatctcca gatacttcac
    45421 ttttaaaccc ttttatctca ctagcttctt ttgaaacagc taaatcaaaa gccagaggac
    45481 cttctacaat tacattttca ccaaattctc cttctttaca agcttttgct aacatatctg
    45541 catctacagt tgcttgcatc ttaggattta ctttctcttt agctgccaaa catgcaactt
    45601 ttacagtttc cattcctaaa gcttttgcag cttttataga attttttaat atctttgcct
    45661 tttgttcata atcaggagct atattcatac ctccatctgt agttataagt aatttatggt
    45721 atttttctaa ctcatatacc ataacatgac ttaataaact atcagttcta agaccatagt
    45781 ctttatttaa cacttctttt aatatgacag atgtatctaa taatcctttc attacaaagt
    45841 cggcttcttt acttgatact aatttaactg ctatttctgc acactctttg atatcatcct
    45901 tatccactat tttgatacca cttaaatcaa atcctatttc ttttgatatt tctcttattt
    45961 tgccttcatt tccaaccaat ataggagtaa ttatatttct ttctacagca tcctttattg
    46021 ccattaaaac ttctttatca tgagctgctg ctacagagag tacaattttc tctcctccct
    46081 taagttgttc taaaatatca tctaattttt ttatcaaaag taacccctcc cttatatata
    46141 tttaactaaa taataccata tttgctatac cttttctcaa tttatttttt atgttataaa
    46201 gaatttatat aactaaaaga cagtttaata ttttattctg ggatttcatc aataactctt
    46261 aaaagctttg caggaacacc acctacaata gtattttctg caacattttt tgttacaact
    46321 gctccagcag cgataattgc attatctcca atagtaactc ctggaactac agttacatta
    46381 gcaccaatcc atacattttt tcctattgtg attggagaag gataagttgt accacgtttc
    46441 tctggtgcaa taccatggtt aagtgtagcc aataccacat tatgcccaat ttgcgtatta
    46501 tctccaatct caatcccccc ctggtcttga aaatggcaac tgctatttat aaaaacattt
    46561 tttcctattg tgatgttttt tccacaatct gtataaaatg gtggaaacat aaaaaatgat
    46621 tcatctacct tttttccaat taactcagaa aataaactac ggacttcttc tggttcatga
    46681 taagaagaat ttaacttact tgtgattttc attgcttcat tactcaactt aaccataaat
    46741 tcatgtattt ctgatttact agaaacaggt tttctttgat tgatatgtgt taaaaattca
    46801 ttgatattca ttttatacat cctttcaata tgtgctttaa tttatttgta cattctaaat
    46861 aatattttaa taaaaattaa tttaatttat ttttattaaa atatcattgc ttcttttagt
    46921 gtaatataca attatatcta tatcaaatat ctatagtaaa tacttaacta tacttaaaaa
    46981 gcatataaat tgatataatt atataataga taagttaata ttgaggaggg ataattatgg
    47041 aaataagagt attaagatat tttttagcaa ttgcaagaga agaaagtata tctggtgcgg
    47101 caaccttttt acatataaca caaccaacac tttctagaca aattatggaa cttgaagaag
    47161 agttgggagt taaattattg gttcgaggaa atagaaaaat caccttaaca aatgaaggta
    47221 ggcttttaca taaaagagca gaagaaatta tatcattagt tgataaggtt gaattagaat
    47281 ttgacaatcc caatgagatt attagtggtg atatatatat aggaagtggt gaaactgaag
    47341 ctatgcgact tatagctaga actgcccatc attttcatca aaaatacccc aatgtaagat
    47401 atcacctttt tagtgggaat gctgatgatg tgactgaaaa attagacaag ggactgcttg
    47461 attttggtat tttaattgaa cctgcaaata tacagaagta tgattatgca caaattcctg
    47521 ctactgatgt atggggttta ctaatgcgta aagatagtgc ccttgcatca caaagcacaa
    47581 taaatccaaa agatttatgc aatatacctc ttattatttc aagacagaca cttgttgata
    47641 aagcaatttc taaatggctt caagacagta atgaaaaact aaacattatt gcaacataca
    47701 atttagttta taacgcttct cttttggtag aagaaggtct gggctacgct ctgtgtttag
    47761 atagactcgt caatactaca gaaaacagta atctttgttt tagacctcta tctcctcctt
    47821 tagaagctaa attaaatatt atatggaaaa aacatcaaat attttcaaag gcagcagaaa
    47881 aatttttact tcaaatacaa aaagattttt cttctatcat gttggataca tctaagttgg
    47941 atacacctaa agaaaaataa atcataataa aaggtgagag tgtctcaaaa tgaactttgc
    48001 actgtataag gcactctttt ttatacaaag taaaatatat gttcatcatt tcagcactaa
    48061 aaaagaggct tatctctatt ttgagatagc cccacttaac caataaaatt aaatacaact
    48121 taacaatatc cttacttatt tattctaagt tctcttagac aagcaatagt aatttcatct
    48181 tgtggattta attcataagc tctttctata tagtaagttg catcatcaat atcaccatta
    48241 tttaaataag ccattcctaa attgcaaagt atttctgggt cttcctttat cttagccgct
    48301 tgttcaaaat actctattgc tttatctaaa ttattcttat aagcctcaca aagccccaat
    48361 tccactatag tatccacttg attaggcttt attatcaata tcttctcaag atacatctta
    48421 gcctgctcta tttcgcccat acccttatat ccaagtgcta tcataaacag caagttccac
    48481 caatccatat gttcttcttc taatggaagt aacttctcta atccttcctt aaacttacct
    48541 tggaatacaa gtgtatatcc ttcttcatat tgaactttaa agtccatctt gcccagattc
    48601 tcttgtacct cagctactaa atcagcatct aaccctagcc ttaacgcttc ttcccaagtc
    48661 agcttagtct ttaaatattg accttgatta taataatggt agcctaagtg ataataacct
    48721 aatgcaaaat tctcatcaac atcaattacc ttttcaagct tagccatggc ttcaagtaag
    48781 aatgcattca ttgccttatc atccatatct ttttgatact gtttagctat ctcttggcaa
    48841 acaatcgcat agttatacat tgcatctaaa tcatctggat acattgttat aaatgctttt
    48901 atatatatta aagaatctgt atgttcacca atctcaaagt attttctcga catatatccc
    48961 atatacgatt tcaaatccaa atcaatatct tttgataaag catttaaaaa cttctcatac
    49021 tctgcattgt ttttaaactt actatctatt ccaattatat atatcattgc atctgctata
    49081 gacattgaat ttaacttatc ttgagcagtc ttttctttta tcccttttac taatacctca
    49141 ttttttatag gtacatctaa tccacctttt ggcacttcat agctttttaa tttaaactct
    49201 ccaccatgtt ttatagttat aaaagctaat tcttctgctt tttttagcaa atatttttct
    49261 atcttaaaat ccattttatc ctcctaaata cttaaatctc tactttatga gttttagatt
    49321 tctcaaatat ttttttatca tcatactcaa ataagactac attttctact tctcttattt
    49381 ctgtatttat atcatttttt aaatccacaa cattaaatct aaatggctca aaatgaacat
    49441 attttattat atgtttagct ggtttatcaa caaaactagg taaatatgtt gataagttat
    49501 cattatcttg taaaaataca tggcatctat tcttaaaatc atccacatct agcttattaa
    49561 aaaactgtgg tatatttgat gttttaccca gtgatatata gtcatatttt aatatatcgt
    49621 tgaatacatc attatctatg ttgatttttt cattatagaa atccatcaat attttatata
    49681 actgattctt tccttgtgcc aaatcaaagt agccattttc atcaaaatac ttggcaaaaa
    49741 cctcaaagaa tttaaaaggg ctttttttat aaaatctgcc tataatatat ctcatagata
    49801 acacaaagtt tttagaattg tagtatctct ccagtatatc ttctatatcc tttagcttca
    49861 aagtttcttc atagcttata taattattgt ataaaaactc atatggagca taatccttat
    49921 atttaaaacc atgctcatct gcaacttttc tcatacctgt ccctttaatc atctttaaaa
    49981 agcctaattg caaatgctct atacctagat taaatacatc attaaaagaa ttttcaaagc
    50041 tcttataatc ttcataaggc agtcctgcaa ttaagtctaa gtgctgatgt atatttctat
    50101 aagatgctac agtttgtaca acatgagaca actttttaaa atcatccctt ctacctactg
    50161 catcaagtgt tttttcattc gttgactgaa cacctatttc aaattgaaaa agaccttctt
    50221 tacaatcagc caaaaactca agcatcttat catctatcaa atacgctgta acttcaaaat
    50281 ggtaagttgt atatccatta tcatttttca taaggaaatc catgatttcc atagccactt
    50341 ttctatttgc attgaatgtc ctatctataa actttatctg tgatactctt gcatctatta
    50401 aagcttttaa atcactcttt atcctgtcta aactaaaata ccttagacct ggaatagtag
    50461 atgataaaca gtattggcag ttaaaagggc aacctcttga tgattcataa tacactattc
    50521 tattttcata ttcttttgga ttcaagtttt cataaggact aggaatctca tccaaatctt
    50581 gaagtaattc cataggctta ttcactatta tctcattgcc ttgtctatat acaagtccat
    50641 ttacatcatt tatttccatc tttccttgca agtgaagtac taagtctcta aaaattaatt
    50701 ctccctctcc ataaagtata taatccacaa aatcatactt tttcattgcc tcataactat
    50761 cataactcac ttccggtccg cccaaagcta ttttagtatt aggtctaatt ttttttagat
    50821 tatcacaaag tttaactata tctcccacat tccagatata tgttgagaat aatattatat
    50881 catattcatt tttatatata tcctttaaaa tatagtccaa atcgttattt atcgtgtatt
    50941 ctttcatatt aacttctatc aaatctctta caaattcttt tagatatctt atagccaaat
    51001 ttgtatgaat aaacttggaa tttaatgttg ttaataaaat tttcaaatat ttctcacctc
    51061 tttttaagat tatactgtct ttttgtaccc cttataggtt aaaatagtat atgtaaagtc
    51121 taaataatat ctatataatt aatttattaa tttcaagtaa tgtgaggaaa ggaagttttt
    51181 tatggaatta attgaaaaag tatctatcaa ctctttatca aaaagagatt tactacttat
    51241 tataaagtct cttgaataca ctaatgaaaa tactcaaatt agtgatttca ttgaccttag
    51301 gaataatata gtaaaggaat tatgtttttt aactgacact aaggaaaaag attttttaga
    51361 ttatctagaa aaaaatagca cactctaata acctaaacct ttttaaactt taatatataa
    51421 atacctgatt tagaatttat ttttatgctt aatatattat cattaaaggt tttcgacata
    51481 actgttattt gattaaatat agggtctatt atagtattac cttcttcaag tcttataaga
    51541 cttcttgggt ctatgctttt attatatgcc ttaactccaa ttttatattt tctcaattta
    51601 acaacatatt cggacataga aaaaataaaa tctatattat cttcatttaa tttactatct
    51661 tcacccaaaa tggataatat agattttttt atgctattaa ttccttcatt ttctacagtt
    51721 ctatcttcca tatatacatc atatagaaca tttaaaacat ttaataaaat actttcttca
    51781 tcataatctt cagatttcaa atcaatgtac ttatcaatta attgtattgc tttaatcctt
    51841 gccatctgaa actttacaac atctgatttg tctaattcta tagaaaatcc tattatcttg
    51901 tctttaatac tctgtagtaa ttcgacatac tctattttac tattatttat aagattgtgc
    51961 ataatggaat tatacaccac agaacctaat aaataatcaa ataaaagttc ttctttttta
    52021 aaataaataa catacttttt tattagttta ataacctcat cttcactttt ttgaatatta
    52081 gtatttgata aaattagtgg taataaaata tttaaaaaat tgatatttcc tattttttct
    52141 ccataaaatc tatagtaaat aagttcatct ctcagtctat tttcgtctat atacacacat
    52201 ctttgcgttt tatcatctat taaggatttt gtatttatta tagttaaatc tttaagagcc
    52261 ctacttgcac tactaaaaga agatgtgtag acttttttta gtaattcgtc attcataaat
    52321 atatcctttc tgaaaaattg aatgtaaata aattgttatt aaaaaaaaag agacagcccg
    52381 tttaagaagc tgtcatatat agggggatag tagtgtacaa aaatcattgt aatctactat
    52441 ctatatatta ttatacgata ctactttttt atatgtaaag catcagtttt cgacatccct
    52501 atattttaca gttatacaaa ttgcgtacta agttcaattt tattcttttt atttcaacat
    52561 tttatcatgc tacattcttt caggagcgtg cattcccaac aatttcagag aattttctaa
    52621 agtttgtttt gttgctaaaa ctaatgcaag tcttgctttt cttatttcca aattttctac
    52681 taaaattgga ttgtcatgat aaaatttatt aaacgcttga gctaaatcta gcataaatct
    52741 agtcactata tgtggctcat ttttctttag agcaagtaaa atattcttat tgaatgattc
    52801 tataactcta agaacttctg cactatcttc atcagctaat agactataat ctatatcaga
    52861 agtcacttct acttctgctt ttcttaaaac tgcacagcat ctagcatgtg tatactgaac
    52921 atatggtcca gtctcaccat caaaactaag cgttctttcc caagagaagg tatagtcttt
    52981 aattctacta ttagataact cttggaatac tactgcccca acacctactt gcttagatat
    53041 ttcatccaca tttttagcat ttgggttttt agctagtata atttccttag ttttatctat
    53101 agcttgattt aaagcatctt ctaaaaatac tactcttcct tttctagtcg acatagtacc
    53161 ttcttcaagt gcaaccatac caaatccaac atgaattaaa tcttttgccc aatcatatcc
    53221 cataagctca attaccttaa accattgttg gaaatgtaag ttttgttgag aaccaactac
    53281 atatatacac ttgtcaaaat cataagtttc ttttctatat attgcagcag ctaaatctct
    53341 tgtcatatat aacgttgagc catcattctt agtaataagt gctggtggca ttttatactc
    53401 ttctaaatca acaattcttg ctcctttaga ctcttttaaa agatttttct cttctaatag
    53461 ttcgataact ctgttcattt tatcagaata aaaactctct cctgctaaag aatcaaattc
    53521 tatatctaaa agtttataca ctctgttaaa ctcttttaaa ctctcatttc taaaccattg
    53581 ccataattct tgtgcttctt cgtcaccatt ttctaattta ttaaaccatg ctcttgcttc
    53641 atcttccatt tctgggtgtt gttcagcttc atcatggaat cttacgtata attttagtaa
    53701 ttctggaatt ggattagact ctactacttc tttttctccc cactttttaa aggccactat
    53761 taacttacca aactgagttc catagtcacc taaatgattt attcttatag tcttgtatcc
    53821 ttgcgaatca tatatcttat ataaagcatt acctataact gtagttctta tgtgccctat
    53881 atggaaaggt tttgctatat ttggagaaga atattcaact attacagttt tatcttttcc
    53941 aaaatcacta tgtccgtaat tttctttttc atctaaaact tttttaatta cagtttctgc
    54001 taattgagat ttatttacaa agaaatttac atatccgcct aattgtatta cttttgttat
    54061 ctctccactt ggttctatac tttccgccaa ttcacttgct atcatgtttg gagcttttct
    54121 aaacactttg gctaatttaa agcatggaaa agcatagtcc cccatatcct tatttggtgg
    54181 aacttctata agtgcctcta tctcttcttt cgataaatct tctatttttt ctttaaggca
    54241 atttgatatt gccaccttaa aatcttgcat tctgttgctc ctctctacat tgttcctggt
    54301 ttatattgtg cttatctctt tatgttaaat caaatttcgt gttttttcaa gtatttcatt
    54361 acagtgtaaa acactttagt aattatgttt tctgtatata ttaaaaatac tataattgca
    54421 gtttttaatc acactattat tgatttttta taagactttt ttctatttta ttgtttcttg
    54481 tactatccag ttgactttat atactttttt taatctttta tctattttca tacgtcaatg
    54541 ctaattttat atacttttct tttaatcttt tattaatttt tatacatcaa tgttaacttt
    54601 atataagttt ttttaatctt ttatctgttt tcatacatca atgtcagctt tatatacttt
    54661 ttttactttt ttatctattt ttatacatca atattagctt tatatacttt ttttaatctt
    54721 ttatctattt tctataaatc tttttcactc ttaactttta ttccttcttc ttctaatagc
    54781 cttgctgtta tacctttccc tggtatcttt ttacctgaaa aactaccatc atatattaga
    54841 ttacatccac aagaggggct accctctttt agtattgctt cgctacatac atataaattt
    54901 gctattttta gagtttcatt agcccctctt acaaagtttt ctgttacatc cttattatct
    54961 ttagtaatta cttttccatc aactatctca gcaggtggtc ttggtgtaga tagaccacct
    55021 aactgctctg ggcatacaag tgtaaattct ttgcctttta aatattcctt gactttttca
    55081 ttatcattat tatcgccact atatttacaa tttattccta ttaaacatgc agataccaat
    55141 atcataaaaa tgtgctccta tacaaattct taatatattc tcatacaaat tactaatgta
    55201 ttcttataca aattatttta atttaacaat tgttactcct gctccacctt ctccatattg
    55261 accacctctt tgtgatttta catgtctatt tcttcttaaa atgtcttgta gccctgcttt
    55321 taatactcct gtacctattc catgtattac tgttacagac tctaaacctg ccacatatgc
    55381 atcatcaaga tacttttcta cttccattat agcttcttct aggtttaacc ctctaaggtc
    55441 aacttcattt tttacactac cagattttga ccttataatg tttctcgttg atttagttac
    55501 atttgttgaa acatctttgc gtgttttttg taaagactta aaaggtagag tcatcttcat
    55561 tataccaatt tgcactactg cttcttttct ctttttatct actgaaacta cactaccatt
    55621 ttgatttaaa gttattacct taacttcttc acctggcttt aagtctttta tctccttatt
    55681 tgataccttt ggaactatca tactttttac tgttggctga agacttccca tagagctggt
    55741 caattctttt ctaagttctt ctatcttacg attcttttct tttgaagctc tttcttgttc
    55801 aagacttcta agttctttta ttataatatc tacttcttct ttagcttgtc ttataattga
    55861 aaatgcttct gatttagctt tttcaatcat cttatctctt tgactgacca atttttcaag
    55921 cttttcgtca tactctactt tcagtttttc aatctcttct tttaatcttt cagcttcttc
    55981 tctatcttct actgctttga ttctattctt ttcaacattc tgtaacacat cttctaaagc
    56041 tatgttttct gtatttatat attctttagc acgtgaaatc acataatcac ttagcccaag
    56101 ttttctagaa atctcaaacg catttgattt tccgggaaca cctataagta acttatatgt
    56161 tgggcttaaa gtttctatat caaattcaac tgctgcattt tctacacctg gtttagtaag
    56221 agcataattt ttaagctcac tatagtgagt ggtagctata catttagctc ctacagaatt
    56281 tatatcttct aatactgcta ttgcaagggc agctccttca acagggtctg ttcccgctcc
    56341 taactcgtca aatataacta aagagtctgc tgttacgttt tgtaatatag atactatatt
    56401 cgtcatatga gatgaaaatg ttgatagact ctgttcaata ctctgctcat ctcctatatc
    56461 tgcaaataca ttatcatata cacacatact acttccataa tcagcaggta tatgaagtcc
    56521 actttgtgtc ataagtgcaa atagacctac agtttttatt gtaacagtct taccacctgt
    56581 gtttggacct gttatcacca atgtatggaa gtctcttcct aaataaattg tatttgctac
    56641 taccttcttt ttatccagca gtggatgtct tccatttttt atgtttaaat atttatcctc
    56701 atttaaagtt ggttctattc ctctcatctg tatagaaagt tttccctttg aaaatgcaaa
    56761 gtccaatctt ccaagtatct cttgattaga aattaagtct tcactaactt ctccaaccat
    56821 agcagaaagc tctgataaaa ttctttctat ttcttcttgc tcacctagtt ttaactgtct
    56881 caattcattg ttcatctcta ctatagtcat tggctctata aaaagtgtcg caccagaaga
    56941 tgactggtca tgcactatac cagctacttg cgacctatat tcagatttta caggtactac
    57001 aaatctatca cctcttagag aaattattgc atcttgtaag tacttttgat aagtagttga
    57061 acttattatt gaatttaatt ttgacctaat ggattgattt ttttgggcta ttcttcttct
    57121 gatatctcta agtgtacttg aagcattgtc agatatttct acttcactaa ttatagcatt
    57181 gtatatctgg tcttctatgt ccttgtatac atatagagaa tttgatagag attgtattat
    57241 tggataatta aaatcttctt catcactact agataagcta tttcttaatc ttctagccac
    57301 tcttaaggta tctgctatca taatcagact tcctgggtca agagaagcac ctatataagc
    57361 tctctttacc ttatcttcta tatcatgaat accttccaac cctactgaac ctctctttat
    57421 aataattgat tgagcttcac tagtttcttc tagcatagat ttcacttcta caaaatcagt
    57481 atttggtact aaattttcta tatattttag acctaaagaa gatgaggctt tcttctttaa
    57541 caaatctatt attttattgt attctagaac tcttaacgat ttctcattca ttttctatat
    57601 tcaccatcct cgatatttta acttttttat ttaattttaa aaatgtatgt tttcaagcat
    57661 ttccaataaa aactgcaagt tttatttctt tttcatttct aaaattatta tattttttct
    57721 cttttagata tattttacac atattttgta ttatactatg tatgtagcta tctatatatt
    57781 atacataaac atgctttatt tgtaatataa tctgttaaaa aatcttcttt aatattttta
    57841 aaggagttta ttttagctta taaaaaaaaa tagctactta tatagataaa ttaaggagga
    57901 acatgagtca tgggaaacgt attagaagga ttaaaaccag aaagtgtttt taaaaacttt
    57961 gagaaaatat ctcaaattcc tagaggttct ggaaatgaaa aaggcataag tgatttttta
    58021 cttagctttg gtaaaaattt aggtcttgaa actattcagg atgaaagctt aaacataata
    58081 ataagaaagc ctgctacaaa aggatatgaa aattgtccag gtgtagttct tcaaggacat
    58141 atggatatgg tttgcgaaaa agaaaagaat gttgaacatg attttcttaa agaccctata
    58201 aaattaagaa ttgatggtga catgatatat gctactggaa ctactctagg agctgacaat
    58261 ggtatagctg ttgctatggg tatggctata ttagaagata atactttaga gcatcctgca
    58321 ctagaagttt tagttactgt taatgaagaa gatggtatga atggtgcaga tgcactagac
    58381 cctagcttaa ttaaaggtca atatatccta aatatggact ccgaggagga aggatactta
    58441 ttagttagct gtgctggtgg taaaacttgt gttgttagtt tacctgttga atacaaggaa
    58501 gttaaaggtg acaaacaagg attattagtt gaggttactg gactattagg tggacactct
    58561 ggtatggaaa ttgttttaca aagagcaaat gctaacaaag caatagctag agtattaagt
    58621 gtattgaatg ttgattatga attagcttct gttgatggtg gtactaagca caatgctata
    58681 cctcgtgaag ctaaatgtgt aatagctgtt aataaagctg atgttgaatc tgctaaaaaa
    58741 caaataaatg acattttaac tgcatttaaa catgagttta ctacttctga ccctggcatg
    58801 acttactcag tagctgaaac ttctgtagac aaagttctta ctaaagattg taaagaaaaa
    58861 gttgttcaaa tgtcttgctt aactcctcat ggagttcaat cagtaagtct tgatatagaa
    58921 ggattagttg aaagttctac taacttcgct ataatcgaaa ctaaagaatc tactattgaa
    58981 tttttaactt ctgttagaag ttctgttatg tctattagag atgaaatcgc tgatagaata
    59041 agacttttgg ctcaagcttt aggtgctaat tacgacctta tagctcaata cccagcttgg
    59101 gaatttaaaa aaggctcaaa attagaaaaa atatgcagtg aaacttatga gaaattaact
    59161 ggtaaagttc ctactgttat ggctctacat gctggtcttg agtgtggatt attacttgat
    59221 aaacttcctc atgctgaagc tatctctata ggaccagata tgtttgatgt tcatactcca
    59281 aatgaacatg ttagtatccc ttctgtagct aatgtttggg attatgttat tgaaatatta
    59341 aaatctatga accaatatta aatttaagtt ttgattctaa gtagatttta attttaagta
    59401 atctatataa aattaactct gtaaattaat actactgtta gtataatatt tactttcaat
    59461 attaacttat agaaataaag cctaatgata gataataaca tgtatcatta ggctttattg
    59521 taatttaaat attattaagc tttattctgt tttaaaatta attcttatac tattttaaat
    59581 ctatttcttc cttgtctctt agaatcataa agagcattat ctgctatttg atacagttca
    59641 tcatactctt gaccaggctt tgctataact acccccatac taatagataa actttctcca
    59701 tttggcaact taatgagatg aatatgattg tatacatcat tacatttatt aataagttct
    59761 tccttattta ttatatcatt gatataaaca ctaaattcat ctccacccaa acgacctact
    59821 atatcatttt ttgcaaaact ttcatcaagt acctttgcaa catcaataag tactttatct
    59881 cctaacaagt gaccataagt atcattaatc gacttaaaat aatcaatatc tataatcaat
    59941 aaagcaccat ttttttcagt tgataaattc aacaaatttt gtgcagttaa ttttctaata
    60001 tatgctgcat tataaatatt ggttaaacta tccctttgag ccttatctaa caatctattc
    60061 ttttcctctt tttcagaatc aatattacat attttcccga ttacatacat tggtattttt
    60121 ctatcattat aaattatttt tgaagtaact ctaatccaat gaaaagtatc atcaagcata
    60181 atagaataca tttcagttgt tccattttct tgtgatttta ttacatcaaa aaacttttta
    60241 ttatattctt tccttatttt atctctttca ttttctatat tgccattttc actttcctta
    60301 tcatttttat ccaaaccata ataagtctca ataccctttt ctggcataga aattatcaat
    60361 ttatcttgct tataatcata ctcaaaaaag tattcacttg tcatttcata caactgagta
    60421 tgttttttga gttctaaaga tatcttctcg ttcatacttg tacgagtatg caaaccaaat
    60481 gccataaatc caataataca aattaataaa ctggctacaa taaaaatagt ctcaattgga
    60541 ttctgttgca taatataaag caacgagaag tcttgtctat atgtagtatt ttggtagaca
    60601 attgattgca ttttttctga tgaaatactt ataatagctt tattaaatat attcaataat
    60661 tcttgtttat cttttttaat tataccaaaa caaatactct ttgctttata agtttgagga
    60721 actagacgca catttttata cttaggttga ttcatatagt actgcataga ataaccttcg
    60781 ccataagtgt aatctgcata gcctttatta acagcttcta tacactcttc taaattatca
    60841 taccaaacta tattctcttc aaactgacca taataattaa tacctttggc tagagctaca
    60901 cgttttccat ctaaactatt ctcatttaat ttattattaa tcatcatagt atattgagta
    60961 gaaagaaaag gccgagacat aactatatta tgttcacgag agtattcata atcataaatc
    61021 attcctgcta caatatcaat ttcacgcttt ttagtcatgt tttctaaatc ttcttgagat
    61081 tttacaggca caagttcaaa ttctaagcct gttttatcac atatatgatt taacaaatca
    61141 attgatatac ctcttaattc acctgtatct ttatctatat tttgaaatgg tggtttgttt
    61201 aaaagtactc ctacttttaa tttttctgtc tctttaatgt aatcagtttc ttcatcagat
    61261 aaaaacattt gattgttctc tggtgtaaag tatttttcat ataaagtagt tgaaaaatat
    61321 gggtctttct gttcaatatt attaattgct gagttaagct tttgagttaa atttgtacta
    61381 cctttaggag taatgaaata aaatggtttt gatgaaaatt ttgctacagt acgtacacct
    61441 tctagtgggt tcatactaac attaagaagt acatctgctt taccactctt tagtgcttct
    61501 agttgctcat catttgtttt acaatatacc aattcaggtg acataagatt cattttacaa
    61561 tactcatcta actctttaag tctagtatca gaattttcta ttacagcaat acggattttt
    61621 ttcacatctt gtgaactcat tatgttatca atatctgtat tttcatataa tgcttgtagt
    61681 actgtatttg ctactccata actatttcct gcataattat atattttttg cattggctca
    61741 ttgtataaca tacctcccat tatatcaatt tcaccatttt ctaacatctt cattaatttt
    61801 gtaatagatt catttatctc tccaggaact tgaacaaatt cataattcca tccagtatac
    61861 tgtgcaattt ctagtaaata ttcatatgta tacccaaaat agttaccttg ctcatctatt
    61921 tcagttaaac ctttttgaat aggataagca acacgaatgg tacgattatc attacctata
    61981 gcgttgatac caaaagaaaa tatgcaagaa gtgaatatag atgtaattac aataattaat
    62041 aaaagtaatt tttttaaatt cactacacaa tcctccatat agttaagatt tacagtataa
    62101 attactgcat aaacttgtag acatgtaaaa atagattagt atataaaagg atatataaat
    62161 ctacttagaa atttaaatat ccttaatata tacaatatat ttaaattata actcatttat
    62221 atgtctatta caacaaattt accctgctaa atacctactc tatatcccat aattttacaa
    62281 gttgtagtga agtttaagtt ctatctcacc tcaaatttag cagtgtttct atttacagtt
    62341 cttttatatt tcacatctgg ataacccaat ataaatgaag tgataacagc ttcgttctcg
    62401 ctcattccta acagttcttt tatctttggc tctacatttg atgccataac aaaaaatcca
    62461 ttataacaaa ttcctaatcc ttgagaatat gccataagtt ccatattaga tgcagccagt
    62521 cctccatcta cataagcact tccacctaga gacatatctc ctacaactac cataagtagt
    62581 ggggcatcat aaaataaaga atcatttccg ttctctttat atcttttgta cattttctta
    62641 aatgtatttt tatagataga acgtacaggg tcattgtcat cagtatctaa tgccaaatta
    62701 taaagacctt gtattgccag ttctttcact tcttttagct tttcttttac taatatgtat
    62761 cttataggct gtctattacc acctgttggt gtgtatctac cagcttccac tatgtttttt
    62821 attttttctt cttctacctc tatatcttta tattgtctta tacttcttct aaatttaata
    62881 aaattcaata acttttcggg ttctaattca aaactttcac gattgtattc tattacttca
    62941 tttttatcaa atccttgcat ttctattgca tctgttgggc aaattgccat acagtgacca
    63001 cagttaatac agagaatatt tttaaccttt gctttatcat ccttaacttt tattgcattt
    63061 acaagacagt ctgattcaca catcccacag cctacacatt tttctaaatt tatgtctatc
    63121 attccaaatt attcctcctt ttaaaaaatt tactttagta taaaacaaat agttgtctaa
    63181 gtcaattttt atttttttaa caatatacta gccttaacta cactttaatg gagaaaaata
    63241 tacataaatt ggaacttaaa ttagaactta ttcaaagtaa aagataaaag aagtagatgt
    63301 ctaaaagtga actttttagt taattagata ttctttattg tatgaaatca agtggatatt
    63361 tatcatttca acaataaaaa aggcttacct ctattttgga tatgtccctg tcaagtagac
    63421 agactaaaaa aaggctatct ttatgcactg agatagcccc ttttcccaac tactattgtt
    63481 tatcttaata ttagtcaata aatttaattt gctataacct gtaagttaca ttttaatttg
    63541 atgtaacttt aaattacatt tttaagtaat atctttaaat tatattctta aaatatatca
    63601 ttaaactaca ttttaattaa tctaaaaact atatcttaat taatctaaga aacttacatt
    63661 ataatctttt agtttcccat tatcatatac aatctttgca ctaaagatat ttccagtctt
    63721 agcccaattt aagaacagcc tgtcaccttc ccacatattt aaatcgaata ttttatcatt
    63781 atcaacccaa attaaatttc cttctttaca atcatttaaa tctttttcag ataattcacc
    63841 ttcaaactca tctgagaaat acaaaaacat ataccaatct tcttcatctt taaattttgg
    63901 aaaagttatc aaccctttat atgacaatga tttaagagta agaccagtct cttcttttac
    63961 ttctctaatt acacattctt ctggagtctc tccttgctca aactttcctc caactcctac
    64021 atacttacct tcatgtatat catctttctt tttatttctg tacaacatca aagtcttgtc
    64081 atctttttct atataacaaa tagttgtaag tttcatgtat ctcgccttgc tttctcttta
    64141 tattctcaac taattatttt cagcactttc aagcacatca cttatattct tcattgcatt
    64201 aagagaaagc tctgcaaatt catcaaatgg aatccctata tcttctatac ttctcattgc
    64261 atctctattt acatttgaag caaatctcgt ttctttcatt cttttaataa cagacttagt
    64321 ctttacactg gtaagttttt tatctggata aactaaagct atagcagtta taaacccagt
    64381 tatagggtct gctgcatata ttgctttttc cattaggcta gttcttgtaa ctcccattcc
    64441 atcatgatga ccaagtattg ctctatacat ttcttcgtca ccgaagtttt cttttttaag
    64501 cagttctact gttgttgtag catgtccctc acatatttct cctggctttc ttccaactat
    64561 atctgaatcc aaatcatgta aaagacctgc cactgcccac tcttcttctt tttctggctc
    64621 tagtcttttg gctaattctc tcataacagc ttcaacagca taacaatgtt ttctcattct
    64681 atcagtttct aaatacttaa ataaaatttc taaagcttct tctctcattt tcaccaatcc
    64741 ccctgttttt tcacatatat gatattttta tatattaata cacataaatt caagttttta
    64801 tatatattca tgtatatttt tcatgttata tctattctac acctttatag tagtgtcctg
    64861 caactgttcc aatttcatct aatttcttat acaagtctgt agcccttttt ccaagtttat
    64921 aattattact caatacctca atgtgagctt caataacctt tttaaccatc tcactatctt
    64981 caactgtaaa atctatccta aatacatcta ttccaatttc ctctaactca tatagattgt
    65041 ccaacataca agtaaccttc gaattgtaaa ttgtacttct acagaatata tcttgtgtta
    65101 tcctataact tgcatccgta aagtctctta aagcataact actttcctta catttagcaa
    65161 ctctcttgtc ctttttacaa tccctaacaa ctactcccat aggacagtat tctgtaacca
    65221 tcataggagc atatccatat attactgctt caatttctac atctgtatat tttaaagttt
    65281 gtttaatttc atttaagttt agttcttgtg acaaacaaac tgtacttgct ccctcttctt
    65341 tgaagtggtt tatactttca ctattgaatg catttaagta gcaatctata tttaagtctt
    65401 ttttcttaaa gtattccata gagccccagt taccaatttg aaccttatta attcctttta
    65461 tattatccaa tatctcaaat tgcttgtact ctttatttct aacaatcctt ggtgctgaat
    65521 agattaattt tttgtcagtg actgctgtat tagagtggtt cttattcaaa gtatctattt
    65581 tacttgtatt tgacaaagta tatatgttat ttgtatttga acccattagt tctttaggaa
    65641 tacctaaaga tgaagaagta tataaatcca tagaaatact tgaatctata gaaatacttg
    65701 agaccatttg taaagctttt gataatgtat ttatatcttc ataatagatt aaatctacat
    65761 tataatttaa tactgcttct aattgctcca agttcttaac tttaactcta atcttaggaa
    65821 ctgtatcaag ttttttctgt ttatttactc tatttggctg gtattttaat ctattcttct
    65881 taaattttct atcttttatc tttattcttt cttcatctaa aagctcaata caatcccttc
    65941 tcatctgatt taacacactt ataggcatac ttacaccttc atccaggtca atttctatct
    66001 cttttaactt atatggtgta tttccaagct tttgaatttg tgtttctatt ttttctttac
    66061 ttaaagccac ctttatagct ttttcaacta ttttgtctcc ttctaccacc gatttatttc
    66121 cacaaaaatc acttataaaa agctctggct ttttacctag tttaatactc acttttgcac
    66181 gtatattagt ttttatgaac tctttatctt gctgaaatgt agcttgtact ctatccatca
    66241 attcgctgtc agaagtctta tatataagct gatttctctt tgcttctcca acaaaatcta
    66301 attctatcaa atccccttta tgtgctattg tagttatctc tccatccttt attattcttc
    66361 caatagtacc tccacctaag ttaattccat cacctttctt aagcgtattt tctagcatta
    66421 ctctaagtct tttgttcttt ctattataat ctaaaacttt tccaatatat agcccttgat
    66481 tattaggtct attagagttc attatatcct taccaacttc acctaatata tatccttttg
    66541 taaactttct attaaatatg gtatacaaat tatttattat ttcctcagaa atacttattt
    66601 ttttcttatc tacaaattca ttaatcgctt ctctatatcc tgaaaccaca gtagctacat
    66661 actctggctt tttcattcta ccttcaattt ttaaagataa tacacctgct tcaattattt
    66721 tatccaaatc ttctatagta cttaaatctc taggactcaa caaataatct ccattacttt
    66781 ttactacttc tcctgtattt atatctatca actcatactt ttgtctacat ggctgtgcac
    66841 acctacctct atttcccgac ctattgccta tcatactact cataaggcat tgacccgagt
    66901 aacatacaca taaagctcca tgtacaaaaa cttctatatc tacagttgta ttttcacaaa
    66961 tccattttat ctcatcaaca tttaattctc ttgctaaaac aactctatca aaccctacac
    67021 tctgaaggta ttttacatct tctaaggaat gtgctaccat ttgagtgctt gcatgtagtt
    67081 caaagtcagg taatagtttt tttataagtc ttgccattcc tatatcctgt actattaaag
    67141 catcaatatc tatatcgtat aaaaatttta catactctac aaaatcttct atttcatact
    67201 gttttatcaa tgtatttaca gtaacaaaga cttgcactcc ccttatatga gagtatttaa
    67261 cagcctcaat cagctcattt ctatcaaagt tatttgcaga tgctctagca ctaaagtctt
    67321 taccacctaa atacacagca tttgctccgt tttgaactgc tgcttttaat gaatcaaaag
    67381 agcctactgg tgcaagtaat tctatttttt tcatattttt ctcctctatt tatacttgtt
    67441 aggttaatat aattatatct ataacttaaa tatttgtatt aaatttatat atttcttact
    67501 atattttaaa ttcttcaatc aatttatata ttagttattt atatttggtt catttgagtt
    67561 aacatataca ttatttacta tatttagtat atttctatta acttatatat tgattactgt
    67621 attttaaatt cttcaattaa tttatatact gcttactaaa tttaaaacat tttaattaat
    67681 ttgtacactg tttactatac ttgaaatact tctattaatc tatatattgc ctactatact
    67741 taagacattt taattaattt atacactgtt tactatactt gaaatacttc tattaatcta
    67801 tatattgcct actatactta agacatttta attaatttat acactgctta ctatacttaa
    67861 aatacttcta ttaacttata cattgcttac tatattttaa attctttaat taatctatac
    67921 aatatttgct atatataaag tatatcaaat aacagcttca tttttttgta aatttacaga
    67981 aagttaattt tcattaaatg aatcatcttt attgataaac ataattccaa agaccactgc
    68041 caaaataaaa aaacatatta gtattgattt ttccacgaaa atttttgtaa aaaaagttcc
    68101 taaaatagct ccagatataa agaatataat aatagcataa tactgtaaac tcttttttat
    68161 cataaaaata ttcttagtat gtatataatg aaataaagtt tctgtagcac ttcttaaatt
    68221 tccagtacac attgtcgttg caaaactatt cccatttact tttctaaaac tctctacttg
    68281 cattgaacaa ataaaagaaa tagcaacatt tacaaacata ttaaatcttc ctctaggaat
    68341 aaatgaaaca ataagtattg taatcatttc aattataatg ataacctgac gccaatgaat
    68401 ctttgtctta ttatttgtaa aatactttct tatcttctcg gctataaata cacctaacat
    68461 aaatgccaaa ataggaatca aataataaaa tgattccttt acattacctt ctgctatatt
    68521 aagcccaaat aaaactatat ttccagtttg tgcattagca aagactttac ctcttaccac
    68581 ataagtataa atatccaaaa atcctcctgt tattgccaac aaagaacata aaaagaatga
    68641 ttcagacatc tgactcttgc ttgtcatata taaacctctc gctttctaat gatagataca
    68701 aaatcaaaat cattttagat tctatttttc attgatataa aaaaattatt tatatttaaa
    68761 tattgtctat atttatacat tatttgtatt tatatagcat tcatatttat ttatatttaa
    68821 acattatcta tatctatata gcatttatat ttatttacat ttaaacatta tctatattta
    68881 tatagcattt atatttattt acatttaaac attatctata tttatatagc atttatattt
    68941 atacattaaa agaagctgtc tcaaaaaaca agagacagca aatcttttag tttattccac
    69001 attttttgca tcattattta accctgtaca ttttaactgt aaatcataag ctttgttttg
    69061 aaactcagaa gctaagtttt cagctatagt agctctttca tttgcttctt caagttgagt
    69121 acttaactcc tcaatcttgt ttttataagc atctaactct gctctagaac cttctgtcgt
    69181 attactaagt tcgaatattt cttgcttttt attttctata atctcaatta actctttcat
    69241 cttagtttca gcttcacgat tttctgcttc tttttctgct atcgtaagct ttaaagattt
    69301 gatttctaat tgaagctctt cattagatgc tccaaccttc ttactcaatt cttcattcgc
    69361 tttaatcaac ttctcattct catctgaaca ttcaaataaa aggtctgata tatttaatgc
    69421 agttaatatc gcagcaactg ataagctcaa tttcgggttt tgacgtgtta ttttatccat
    69481 ttctttgtct acaaaatcag caatactaat cataaacttc tctgatttgt ctccaaccat
    69541 tggatattca gcgccatgga ttttaaccat tactttgttc atcctaacct cccccgacat
    69601 tagttgttaa tttgatctta agttagcatt taatttttcg cttaattcac ttaatatctt
    69661 atcatgcacc ttagctacat cttcatctgt tagagtttta tctttacttc tataagttat
    69721 tgaatatgca attgacttgt atccagcttc tatttgagaa cctttgtaaa catcaaataa
    69781 cttgtagctt tctactaatc cttgaccatt ttcctttatt atatcttcta tttgttttac
    69841 aaatacatca tctttaacaa taagagctat atctcttgat gtagatggat attttggtaa
    69901 tggcacataa ttctttgttc tatcagaatt atcaaataca aagtcaatat ctatttcagc
    69961 gacataaact ctttgaccta gattgtagtt ttctataaca tctggatgca attcacctaa
    70021 tgtacctaca tatttattat tatacactat tttagcacat ctaccagggt ggaaggtagt
    70081 attattatct tgaggttcaa tttcataacc tttaaatccg acatttacaa gtatagtttc
    70141 tatagttcct tttagtgcaa agaagtcaac atctttacca tacataccta cacacattct
    70201 attttcttcc ttaggtaatt ctgaatcttg tgggatgaat atatgtccac actcaaatgc
    70261 agatacttct tctattttat gagatacatt agttgataaa acatctaaca tatttggtat
    70321 taaagtagtt ctcattacag aagtttcttc tcctaatggg ttaagtaatt taacaaaatt
    70381 tctctttgca ttaccttctg gtactcttat cttatctact cccttagggc ttacaaatga
    70441 atatgttaat atttcattta atcctacagc agttgaatta tcttttaaag catccatgaa
    70501 tttttgtttt gaagttttaa ttcctgctgt cgtatttcct tctaattgta cagaaggtat
    70561 attctcaaat ccataaattc tagctatttc ttcccataca tcagcttctt gttccatatc
    70621 tgttctaaag cttggtacat ctatttctaa tttatcatta gctaccaaat tacatttaaa
    70681 ctctaatgat tctaaaattc ctacaaactg ctccattggt acatctacac ctaataggtg
    70741 gttaattctt tgaggattta ctaccaattt tttaggttct ggtttatttg gatatacatc
    70801 tacaacacct tttaaaactt ttcctgctcc taacatttca acaagttgtg cagctctatt
    70861 tgctgctatc tctgcaagat tagggtctaa gtctttttca tttcttgaag atgcttctga
    70921 cctaatacca acttttttag ctgtcattct tatgttttct ggtttgaaat tggcactttc
    70981 aaaaagtaca gtcttcgtat tagaagttat ttctgagtta gcaccaccca ttacaccagc
    71041 taaaccaagt gatttttctc catttgttat aactagcata tctttgtcta atgttctctc
    71101 aacatcatct aatgttacaa gtttctctcc atctttagca tttcttacta ctattcttcc
    71161 agtctctact tgatttatat caaaagcatg aagtggttga ccaagctcta acattacgaa
    71221 gtttgttata tcgactatgt tacttatagg tcttactcct gcttctgtaa gtcttctttg
    71281 catccaatat ggagaaggtt ctatttttac atctgtaacc attctagcaa catatcttct
    71341 acataaatct ggattatcta tctcaacttt gaaatctatc tcttcgtcac tttcttttac
    71401 ttcgatttca ggatatttta cttttgttcc tatagttgca gctgcttctc tagctatacc
    71461 catcatgcat ttacaatcag gtctgtttga agttaattca aaatctatta aagcatcttt
    71521 taatcctaaa acatctttta tatcttttcc taattcataa gaatcttcgt ggtctaaaat
    71581 atatatacca cctcttttat actcctcaat gtaatgttca tctataccta gttcagctgc
    71641 tgaacacatc ataccatctg ataattcacc tctgaaatca gtctgtttga tttcaactcc
    71701 tccaggtaac ttagaaccat ttacagctac tggaatataa tctccttctg atatatttgt
    71761 agctcctgta actatttgaa caactttatc tccaatatct actttagtta caaccaactt
    71821 atcagcattt ggatgttgtt ttatttctaa aatctttcca accaatatat tttctatttc
    71881 ttcaccataa taatctattg tttcaacttt agttcctgtc attgtcattt tatcagcgaa
    71941 ctcttttaca tccatgtcta tatcaacata gtctctaagc cattttaaag atactaacat
    72001 ctacataccc tcctaattaa aattgattta agaatctcat atcattttcg aataataatc
    72061 taatatcatc tatttcgtat ttaagcattg caagtctttc aaccccaact ccaaatgcaa
    72121 atccactgta aacttctggg tctattccac aatttctaag cacatttgga tgaaccatac
    72181 ctgaacctaa tatttctatc caaccttcat atttacacat tgggcaacct ttaccaccac
    72241 atttgaaaca agtaacatca acctctgcac ttggttctgt aaatgggaag ttgtgaggtc
    72301 taaacttagt tttgatatca gaaccaaaca atttttcaac gaagatatcc atagttcctt
    72361 taaattctgc catagtaaca tcttttccaa caacaagccc ttctatctga tggaacattg
    72421 gtgagtgtgt agcatctggc gagtctgacc taaaacatct acctggtgca attactttta
    72481 ttggtaactc ttgacttctc atagttctta cttgaactgg agatgtttga gttctaagta
    72541 ataccccatc attgatatag aatgtatcgc tcatatctct tgatggatgg tctttaggag
    72601 cgtttaatgc gtcaaagttg ttttcaacag tctcaacttc tggcccttct gctatagaga
    72661 atcccattcc gataaatata tctgttactt catctataat ttgagttatt ggatgcttct
    72721 tcccaacctt taaaactttt cctggttgag taacatctat cacttcctct tttaattttc
    72781 tttctttttc aatagcattt atttcttctt ttttagaatt tatgctaagt tcaatgtttt
    72841 ctcttacctc attggcaacc ttaccaacta ctggtctttc ttcagcagat aatttaccca
    72901 tttctttaag tatggcagtt atctcacctt tttttcctaa gtacttaact cttaaacttt
    72961 ctacactttc tatgctttgt gcttctttta tttcagccaa agctgcttca cgtaaagcaa
    73021 gtaatttttc ttgcacacat atcacccttt cgtttttttg tataaaaaaa gcccctcaat
    73081 ccctgtctag ggacgaaagg ctatagtttc gcggtaccac cctagtagtt taacaattta
    73141 aaaatcatca aaccacctct aacaaactta acgcgttttt gacgtcaaag cctactgtaa
    73201 aatttcagct ctgttactcc agagggaact tctcatgacc tcttagaaaa cactcccagc
    73261 ctaggtgttt atctctttac taagtttaat caaaatactt tcctctttca ttgcatttac
    73321 aatattatat tgtttatttt agtattatat catttccatt caaattatgt gactattttt
    73381 aatatatatc caata
//
LOCUS       DAEHWO010000011        65626 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEHWO010000011 DAEHWO010000000
VERSION     DAEHWO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 65626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65626
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.011"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            454..3096
                     /gene="adhE"
                     /locus_tag="KNP54_000954"
                     /gene_synonym="adhC"
     CDS             454..3096
                     /gene="adhE"
                     /locus_tag="KNP54_000954"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBF0891876.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3456..3797)
                     /locus_tag="KNP54_000955"
     CDS             complement(3456..3797)
                     /locus_tag="KNP54_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891877.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENEDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(3824..4495)
                     /locus_tag="KNP54_000956"
     CDS             complement(3824..4495)
                     /locus_tag="KNP54_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891878.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(4507..7083)
                     /locus_tag="KNP54_000957"
     CDS             complement(4507..7083)
                     /locus_tag="KNP54_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0891879.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YTNKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            7291..8226
                     /locus_tag="KNP54_000958"
     CDS             7291..8226
                     /locus_tag="KNP54_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBF0891880.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            8245..8982
                     /locus_tag="KNP54_000959"
     CDS             8245..8982
                     /locus_tag="KNP54_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891881.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(9167..14224)
                     /locus_tag="KNP54_000960"
     CDS             complement(9167..14224)
                     /locus_tag="KNP54_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBF0891882.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSNLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(14249..14668)
                     /locus_tag="KNP54_000961"
     CDS             complement(14249..14668)
                     /locus_tag="KNP54_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891883.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            complement(14902..15153)
                     /locus_tag="KNP54_000962"
     CDS             complement(14902..15153)
                     /locus_tag="KNP54_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891884.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            15242..15973
                     /locus_tag="KNP54_000963"
     CDS             15242..15973
                     /locus_tag="KNP54_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBF0891885.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            16032..16943
                     /locus_tag="KNP54_000964"
     CDS             16032..16943
                     /locus_tag="KNP54_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0891886.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            16994..17806
                     /locus_tag="KNP54_000965"
     CDS             16994..17806
                     /locus_tag="KNP54_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBF0891887.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            17915..18607
                     /locus_tag="KNP54_000966"
     CDS             17915..18607
                     /locus_tag="KNP54_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBF0891888.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            18694..19635
                     /locus_tag="KNP54_000967"
     CDS             18694..19635
                     /locus_tag="KNP54_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891889.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            19672..20829
                     /locus_tag="KNP54_000968"
     CDS             19672..20829
                     /locus_tag="KNP54_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBF0891890.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            20981..21541
                     /locus_tag="KNP54_000969"
     CDS             20981..21541
                     /locus_tag="KNP54_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBF0891891.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            21569..22060
                     /locus_tag="KNP54_000970"
     CDS             21569..22060
                     /locus_tag="KNP54_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891892.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            22289..22840
                     /locus_tag="KNP54_000971"
     CDS             22289..22840
                     /locus_tag="KNP54_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0891893.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            22926..23858
                     /locus_tag="KNP54_000972"
     CDS             22926..23858
                     /locus_tag="KNP54_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBF0891894.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            23913..24776
                     /locus_tag="KNP54_000973"
     CDS             23913..24776
                     /locus_tag="KNP54_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBF0891895.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            25023..26885
                     /locus_tag="KNP54_000974"
     CDS             25023..26885
                     /locus_tag="KNP54_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0891896.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGSGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            26888..28354
                     /locus_tag="KNP54_000975"
     CDS             26888..28354
                     /locus_tag="KNP54_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBF0891897.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASAIATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            28378..29214
                     /locus_tag="KNP54_000976"
     CDS             28378..29214
                     /locus_tag="KNP54_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0891898.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            29780..31363
                     /gene="asnB"
                     /locus_tag="KNP54_000977"
     CDS             29780..31363
                     /gene="asnB"
                     /locus_tag="KNP54_000977"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBF0891899.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDRYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(31428..32024)
                     /locus_tag="KNP54_000978"
     CDS             complement(31428..32024)
                     /locus_tag="KNP54_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBF0891900.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEIAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(32051..32578)
                     /locus_tag="KNP54_000979"
     CDS             complement(32051..32578)
                     /locus_tag="KNP54_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBF0891901.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            complement(32940..33938)
                     /locus_tag="KNP54_000980"
     CDS             complement(32940..33938)
                     /locus_tag="KNP54_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBF0891902.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            34615..35814
                     /gene="hadA"
                     /locus_tag="KNP54_000981"
     CDS             34615..35814
                     /gene="hadA"
                     /locus_tag="KNP54_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBF0891903.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            35853..36653
                     /gene="hadI"
                     /locus_tag="KNP54_000982"
     CDS             35853..36653
                     /gene="hadI"
                     /locus_tag="KNP54_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBF0891904.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            36668..37894
                     /gene="hadB"
                     /locus_tag="KNP54_000983"
     CDS             36668..37894
                     /gene="hadB"
                     /locus_tag="KNP54_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBF0891905.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            37894..39021
                     /gene="hadC"
                     /locus_tag="KNP54_000984"
     CDS             37894..39021
                     /gene="hadC"
                     /locus_tag="KNP54_000984"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBF0891906.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            39069..40202
                     /locus_tag="KNP54_000985"
     CDS             39069..40202
                     /locus_tag="KNP54_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBF0891907.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            40235..41020
                     /locus_tag="KNP54_000986"
     CDS             40235..41020
                     /locus_tag="KNP54_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBF0891908.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            41039..42076
                     /locus_tag="KNP54_000987"
     CDS             41039..42076
                     /locus_tag="KNP54_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBF0891909.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            42559..44190
                     /locus_tag="KNP54_000988"
     CDS             42559..44190
                     /locus_tag="KNP54_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0891910.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(44325..45251)
                     /gene="fba"
                     /locus_tag="KNP54_000989"
     CDS             complement(44325..45251)
                     /gene="fba"
                     /locus_tag="KNP54_000989"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBF0891911.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            45581..45910
                     /locus_tag="KNP54_000990"
     CDS             45581..45910
                     /locus_tag="KNP54_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBF0891912.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESIDLAFTVFEKEKY
                     YENGEHF"
     gene            45910..46632
                     /locus_tag="KNP54_000991"
     CDS             45910..46632
                     /locus_tag="KNP54_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBF0891913.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            46659..48020
                     /gene="rlmD"
                     /locus_tag="KNP54_000992"
     CDS             46659..48020
                     /gene="rlmD"
                     /locus_tag="KNP54_000992"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBF0891914.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVLL
                     RRK"
     gene            48418..50481
                     /locus_tag="KNP54_000993"
     CDS             48418..50481
                     /locus_tag="KNP54_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0891915.1"
                     /translation="MTKIILSNYRCFGEEPTTIEINNLTGFIGHNSSGKTALLSALMK
                     LFGEKSSDRIIERSDFHIPESIDPDSISKNELYIEAQFEFPELERGKDSISIPVFFKN
                     MVVSEPGGKPYLRIRLEANWEKSSNPEGSIDSNVYYITSTTEEINPEDKRNIKRYELD
                     QIKMIYVPAIRRPDEQLKNVSGTIISRLLNGISWSEQTKARIKTKASETEEIFFEEKG
                     VESLKKSLETQWNSYHKDIRYSNPKINFNSTDLETILKKVEVTFSPTGTHRDYRVEEL
                     GDGLRSLFYLSLVNTFLEIEEEILKSINDGKEEDIFTLIPPVLTIVAVEEPENHISPH
                     LLGRVVEKLNFISTKENSQTILTSHSPAIVKRIEPTDIRYFRICKEYECTKVKSIILP
                     NEEKEAEQFKFVKESVLAYPELYFAKLVVLGEGDSEEIIIKQMIELKAESVDSSEISI
                     VPLGGRHVNHFWRLLNDLEIPFITLLDLDRERDGGGWGRIKYAIQQLINIGHDKNVLL
                     YTCEGISQDNEFKEMHTWDVTDTENMAKWIEMLKGYDVYFSAPLDIDFAMLQSFKDKY
                     ISALTSAEGPRIKDHGKIQDIVINEDAEDESLKAAYKDRIDSDIKSTLKQEGGDGSTY
                     TEGEKELMIWYSYFFLGRGKPTTHLSLFSNNTDIDFESFPYCLKEFVNSIIEKMIDDS
                     GGGRK"
     gene            50478..52343
                     /locus_tag="KNP54_000994"
     CDS             50478..52343
                     /locus_tag="KNP54_000994"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024642.1,HMM:NF024754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBF0891916.1"
                     /translation="MKRNWVSKEDWSPAAGFRLEVEAMNTVINDKNTLVVAGPGAGKT
                     ELLAQRACFLLETNTCRYPKKILAISFKKDAAENLKERLELRCGKELASRFESKTYDA
                     FAKEIVDRFRNSLDEAYRPLNNYNIAENRDVRRAFEIAGLNFRGNQTEFNKVYGNKLS
                     INKLPLHTDFVDKIFIDAWNVLLKGNKDTNFVSSLTFGMISRLAEYLIRTNRYIKKAI
                     EMTYSHVFLDEFQDTKSIQYDLVKACFFKTETIITAVGDGKQRIMLWAGARKSIFEDF
                     QNDFLSQKRTLIMNHRSAPRLVEIQKAMYNSLNEEAIDLKTNEKWNYEDGEVYLRLFE
                     DYIKEADILSEEIVELVETGIEINEICILVKQSVDIYSKEIINKLSERNIKARNEAMY
                     QEILKEDIIKTLVSLFRLSLSDRNPDDWDYIYDILGELYGIDEGYNPKILNDFITKVE
                     LMINDLKVNLNITDEKQFSDLVDSKVEYISYEKFASKFQKYKSKDYFDDLVDKFKKLV
                     WIEYNETKDWIKAIDNFEGKNSIPIMTIHKSKGLEYDTIFFVGLEDSAFWNFKNQPDE
                     DRCAFFVALSRAKRRIDFTFSLDRPAGFSNSQKHYCINEFYELFDNTEIVKKIEY"
     gene            52467..53281
                     /locus_tag="KNP54_000995"
                     /pseudo
     CDS             52467..53281
                     /locus_tag="KNP54_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728762.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            53306..53794
                     /locus_tag="KNP54_000996"
     CDS             53306..53794
                     /locus_tag="KNP54_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBF0891917.1"
                     /translation="MYEKDYKQYIKLDIPIDEAKIKNRFEIRLKNERAYHAAVDLLAN
                     RDEEKTAFSIINRYIRFVDKDDEKIRSEWKTNDQWSYFIGEGRAKLKLTTNPEPYNIQ
                     KTLNWLSRQVAPTLKTIKRLDSLNNSTLIEGLIRYARLTDKHKKIIEQNSVNVEDIIY
                     DE"
     gene            54308..54535
                     /locus_tag="KNP54_000997"
     CDS             54308..54535
                     /locus_tag="KNP54_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0891918.1"
                     /translation="MDIVKVFANNVRKYRNKKGLSQEAFAEKAGLHRTYICAIERKKR
                     SIALDNVQKIADALEIETYLLFIEGEEKECL"
     gene            54532..57471
                     /locus_tag="KNP54_000998"
     CDS             54532..57471
                     /locus_tag="KNP54_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBF0891919.1"
                     /translation="MKKLPIEKLIENLGFSGSKNLVNIDMLTKLDISKHDVKTLKVIN
                     PYAIYLVNSKPFILFIESSFEEKKLQQISKLIWNAQIPIAFICDSNSVKIFNGKALDL
                     KSYLIEEIYNQSIEDFSEESEFSYLKISDPLFWDQYTKQYTKTHLNDYLLDNITSLTN
                     KLKKKYKVKFATKLVLRLIFIRYLIDRGVDIAYKNFNHDIKASQKELLKITKNKVELY
                     ELFKYLKEKFNGNLFELNDEINNTCLTDEVFILLSDFLSGKISIDNGQMSLFSMYDFN
                     IIPVELISNIYEILLGKEIRNKDNAFYTPNYLAEYILDKTTLEFLKNNRQYKILDPSC
                     GSGVFLVNSFRRIIDMNLGDKLFCEDDKLLKELLLSNIYGIDINEDAIDVTIFSLYLT
                     ILDYKDPKILSEFKLPNLKGCNLIASDFFDDNKLESLKKINFDFIIGNPPWGSVSDGL
                     HLDYCNKNGYNDMQQNKEISRSFIFRAKDFSSRNTVCSFVVHSKILYTQKKPSKKFRE
                     FLLKKSQIFSVVEMSSVRKLVFKNADAPAAVISFKYNESEENLNNRIIYTSLKPNVFF
                     KLFNIIVIEKYDVKYISQKLLLENDWAWKTIVYGFSKDIDIIMNIKKKYQTVNEIILK
                     NSFVHGTGIQINGNESHDATHLKGKWYVDSKKGIDSFYVDINKGKELTQDKMRRPKAN
                     QQEIFIPPYVLLKKGVDTKTYRYRAAFSNDAFVYSDAVTGICGKKDNLTTLYCLTGML
                     NSSFYSYLNIMLGTSIGIEREQGFSTEIFTYPAIESDEIANLVVKIQEATKLEKTTMF
                     LNEKNSCKYIKQLDKLILKSFNLNDDKFIDYAINIQIPELTNSKSTNIYRKITKEDLI
                     NYSECFKEQFSSIYRRVGKSISISVYPKILNRFTVFELEVTDEKTDREIMVKAEADNN
                     MELFTKIIRYDYNDVFHQIRDIIHFGENSFYIIKPNCYKYWHPAIAEMDLADVLDQIL
                     SDTGGEE"
     gene            57471..58145
                     /locus_tag="KNP54_000999"
     CDS             57471..58145
                     /locus_tag="KNP54_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891920.1"
                     /translation="MGGFKNSSLNFYLKQGLYEIIIDGLIDCCLLMSKSCIEQSRKIL
                     NHEEKIRTHLVENYLENDIERRKTSLSKQHLRFEVEAQENYDNKNESYEGRVDIKVIS
                     KDTLADRRAYYIIECKRIDGKETLNKKYITEGVQRFITEKYSSHYGKNIMLGFIVKDI
                     NIQSNIQKINSLNQNILYTYIDTDMLTVRSDSENNYAVCESKYKVKSKLLLLNHIFYN
                     FSSIIR"
     gene            58306..58722
                     /locus_tag="KNP54_001000"
                     /pseudo
     CDS             58306..58722
                     /locus_tag="KNP54_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003455547.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            58682..61129
                     /locus_tag="KNP54_001001"
                     /pseudo
     CDS             58682..61129
                     /locus_tag="KNP54_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            61269..61691
                     /locus_tag="KNP54_001002"
     CDS             61269..61691
                     /locus_tag="KNP54_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891921.1"
                     /translation="MRLEDIIDKESYEEKYDDLTVEIKKLSKEKKTLKASLINEKSIK
                     ARLREFRKILERNELLEKFDRYVFASIVDKVIVGVINEDGIVDPYKITFVYKTSFDDK
                     QDGHKFINKSPLETYSKDNNDNKKKCSYTNNETLRDCS"
     gene            62229..63263
                     /locus_tag="KNP54_001003"
     CDS             62229..63263
                     /locus_tag="KNP54_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBF0891922.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            63350..63553
                     /locus_tag="KNP54_001004"
     CDS             63350..63553
                     /locus_tag="KNP54_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBF0891923.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            63724..64884
                     /locus_tag="KNP54_001005"
     CDS             63724..64884
                     /locus_tag="KNP54_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBF0891924.1"
                     /translation="MKLSKILLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            65143..65283
                     /locus_tag="KNP54_001006"
     CDS             65143..65283
                     /locus_tag="KNP54_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891925.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
BASE COUNT        25248 a         7493 c        11127 g        21758 t
ORIGIN      
        1 atatattttt taaaactata cagttgttat aaaaagaaaa attgcataca agtcaaaaat
       61 aagtgttatt ttataaaaat acgacaaaaa ttttatttac tacttataca aataacatgc
      121 aaataacata taaaatttaa taagtaaaaa aaatgaaaga tataaattat cattttagta
      181 ttttatttag tcgaagtaaa ttattcaaat gaaatatatc tcatttagat aaaaaatttt
      241 agtaaaagta aaaaaaataa tatatttgtt aaaaaataaa ttgacaaaat attcagaaaa
      301 aaacttcttg acctaagaga gtaaaataaa taaaatctaa ggtatagaga tgaaatctat
      361 aaaattattt taagtataag ttaaaaatat agatgatgca tttaagattt ataaaaatta
      421 gagatgcata attattttag ggaggttttt agtatggaga aaaaagaaaa ggtagtagaa
      481 aaatcaaatg ttgaagtatg tagtcctgaa attgtcaaca gtgttgaaac attaagaatg
      541 agattagaag aaattagatt ggcacaaaaa gaatttgcaa catttacgca agaacaggta
      601 gataagattt tcttagctgc ttcaactgca gctaatcaac aaagaatacc tctagcaaaa
      661 atggcagtgg aagagactgg tatgggtatt gttgaagata aggttataaa aaaccatttt
      721 gcctcagaat atatctataa tgcttataaa gatactaaaa cttgtggtgt catagaaaaa
      781 gatgaagcat ttggttttac aagaattgct gagccagtag gtgttttatc agcagttata
      841 ccaacaacta atcctacatc aactgcaata ttcaaatccc taatagcact aaaaactaga
      901 aatggtataa ttttctctcc tcatccaaga gctaaaaact gtactataga agcagctaga
      961 gttgtacatg atgcagcagt taaggcagga gcaccaaaag gacttatagg ttgggtagat
     1021 gttccttcga ttgaattaac taatgttgtc atggcagagg cagaccttat attagctact
     1081 ggtggacctg gaatggttaa atctgcatac tcttcaggta aaccagctgt cggagttggg
     1141 cctggaaatg tacctgcaat aatagatgag agtgcagata taaaaatggc tgtaagttca
     1201 atcttagtat caaaatcatt cgataatggt atgatatgtg cttccgagca agctgtaata
     1261 gtaccagaaa aaatatatga agaagttaaa aaagaattta aatatcgtgg agcacatttc
     1321 ctaaataaag aagaaactga aaaagtagga aaagtagtaa taattgatgg ttcattaaat
     1381 gccagaatag ttggacaacc agcacatgta atagccaaaa tggcggatgt agaagttcca
     1441 aaaacagcta gaataataat tggtgaagta gaatctgttg aattaaatga accttttgca
     1501 catgaaaaac tttctcctgt acttgcaatg tacaagtcta aaagttttga agatgcagtt
     1561 gctaaagcag aaaaattagt tgcagatgga ggctatggtc atacatcttc attatatgca
     1621 gactctataa atcatccaga gagagtagaa aagtttgtaa atgctatgaa gacttgtaga
     1681 gtattagtta atactccatc atcacaaggt ggtataggtg atttatataa ctttaaattg
     1741 gcaccgtctc ttactcttgg ttgtggttct tggggtggaa actcagtatc tgaaaacgtt
     1801 ggagtaaaac atttgcttaa tatcaagaca gtagctgaaa ggagagagaa tatgctttgg
     1861 ttcagagcac cagaaaaggt ttatttcaaa aaaggatgtt taggtgtagc agcaagagaa
     1921 tttaaggatg ttatggataa aaagaaagca tttatagtaa cagattcttt cctatataat
     1981 aatggatata ctaagaaatt aactgattta ttagatgaga tgggaattaa gcatactaca
     2041 ttctttgatg tagctccaga cccaacatta gcttgtgcaa gagaaggagc taaagctatg
     2101 gctgatttcc aaccagattt aataatagct gtaggtggag gaagtgcaat ggatgctggt
     2161 aagataatgt gggtaatgta tgagcatcca gaagtagatt tccaagactt agctatgaga
     2221 tttatggata taagaaaaag agtatatgta tttcctaaga tgggtgaaaa agcgtatttt
     2281 gctgctatcc caacttcagc aggaactggt tcagaagtaa ctccatttgc agttataact
     2341 gaccaagatt caggtgtaaa gtacccatta gcagattatg aattaatgcc aaacatggct
     2401 ataattgatg ctgatatgat gatggagatg ccaccaagat taacagcagc atcaggtgtt
     2461 gatgctttaa cacatgcatt agaagcatat gtatctatgt taagaactga accagctgac
     2521 ggtctagcac tacaagcagg taaaataata tttgaatatt tacctcgtgc atataaaaat
     2581 ggaaagaatg ataaagaagc aagagaaaaa atggcaatgg catctactat ggcaggaatg
     2641 tcttttgcaa atgccttctt aggaatatgt cactctttag cacataaatt aggtgcattc
     2701 caccatgttc aacacggtgt tgcaaatgca ttattaataa atgaagtaat caagttcaat
     2761 tgtgcagaag ctccaaataa gatgggtgca ttctcacaat acagatatcc tgattgcata
     2821 caaagatatg ctgaatttgc ttcttttgca ggtattaaag gaagtacaga ccaagaaaaa
     2881 gtagataatc ttataaaagc aatagatgaa ctaaaggcaa aagtaggtct tcctaagact
     2941 ataaaagagg ctggagtaga agaatctaaa ttcttagaaa gattggatgc tatggttgaa
     3001 caagcttttg atgaccaatg tacaggtgct aatcctagat acccattgat gagtgaatta
     3061 aaagagatat atctaaaagt ttattatggt aaataatatc tattgtgcaa cataggttct
     3121 attgggtttg tatataaatt attagatttg aatataaata gagttttatt agagacacgt
     3181 agaagtaact ataaataata gattataatt taaattctaa atggaaatga taaaaagtca
     3241 gtaatttaat ggtaatttcg aatatgtgta tttaatcaat taactttaaa attagtcgga
     3301 aaattttttt attacatata attttaaagc ataatatata aaaaacttta tgaaaaaatt
     3361 ataaaaatat tcagaaaatt ctattgacta atttatttat catgatataa taagtttaga
     3421 aaagaaaaaa attggggcct attaaggccc ccttactatt ttttgataga tttatttaaa
     3481 attactttct cattttgatt ttttatattt attatagagt cagtataatc cacttcaaag
     3541 ttggcaaaag cagagaataa atctatatct cttaacaaat gaattgtcat acattgattg
     3601 ttcttattta gccttagaat caatgctctt acaaatggaa attgtattct agaattaaat
     3661 aagttagaac catcagtatc tatatctaag ctacgataat taatatctat aaatatatct
     3721 acatcttcat tttcttctct tattattctg tagtcaaaat ccaagtttaa atttaaatta
     3781 cctaaaatca ataacattta aatcctcttt tctataaata gttttagagt gttaatttaa
     3841 gctctccatc tattatagat ataattctat ctgcttttct agcaatattt tcattatgtg
     3901 ttattattat aagtgtttgg ttatattttt ttatagaact ttttagtaaa tccatgactt
     3961 cttctgtagt tttactgtcc aaatttcctg ttggttcatc tgctaggatt atacttggtt
     4021 ttgcagataa agcacgtgca atagcaactc tttgctgttg accaccagat aattggttgg
     4081 gaagatgatt tttcctttca ttaagaccca ataaatttat aaggtcatca atatattctt
     4141 tatctatttt tttattgtct aactttagtg gtaattctat attttccttt acatttaata
     4201 caggaattaa gttatactgt tgaaagacaa atcctacctt ttgtcttcta tatcttgcta
     4261 attctttatc tgaaagacaa catatatctt taccatctac ctttatagta ccattacttg
     4321 gtctttcaag accacctact aaatgtagaa atgtactttt cccacttcca cttggtccaa
     4381 ttatagcaac aaattcgcct ttatttattt ttaaatttgc attctttagt gcatgtacag
     4441 atgtttcctt ttttccataa atcttaccta agttaatagt ttccaatata ggcataatta
     4501 ttcctcctat tctgtaatgt ttatagcttc aactatacta attttattta tctttcttga
     4561 tggaatatat gtagctagaa tacctacaat tatatttgct acaacaacta gtatatatat
     4621 tttgtaatct attgaaaatc ccaatccata tgatacaaag ccctgcatat aatacatttt
     4681 aaattgtatt ataattcctg acacgatagt aattatactt gagagtacac catataatat
     4741 tccttcataa agtatcatat ttttaaagcc tctctcagag ataccaatag ctcttaacat
     4801 tccaaattca ctagttcttg aagttaagtt ataacttatg ttgtttatta tgttaagtac
     4861 actgattatg aacattattg ctactatacc ataactataa atcatagttc tagatgtcat
     4921 cttatcagaa ttttcttttt ctaccatcat atctactgtt gtagttccag gaacttcact
     4981 tccaatttta cctaaaaggt tatttatttt tttcttgttt gcattttcat taaggtctgc
     5041 ataaactaag ttatacttat ctacaccagt taattttttt aggtattcgc tactcgttat
     5101 tacatctaca ccatcatctc cagagtacat accattatct gcaaaaggat aacttataat
     5161 agctccaact ttaaattcat attctaagta ttcataatta tcttttagac tttcataaag
     5221 acctgtatcc atcccaccct ttggatattt gacttttata gtatcaccta cttttatatc
     5281 tacagctggt gttccttcac caggagtaaa agtctttgtg tatttctgtg ttttagaaat
     5341 ttctggtaca tatacaatag ctaaattttc ttttttcatt tttttcaagt ttatatttcc
     5401 acttactaag tatttttcta atgactttat catctcatca ttataacctt ttagcttttg
     5461 ctttagtgta tatttgccag tagtcttatt ttttatgaac agaggattta gcttataata
     5521 aggagttgaa tttatagctt cgtagtaatc taatctattt attttattta cctctattct
     5581 tgtgtttaag atactagcag ttttgacttt gtcaattcca tctatatttt ttattttatc
     5641 tatctgatta tcattaaacc cttttatatc tttaaaagaa gtattgttac caatttcatt
     5701 gagataaaca tttgatagaa taaaatctgc attcatatat gtttgttctt gagtagattt
     5761 gttttgcaca tctaaaaaag aatatttata attgtctttt atgacgatta tacctcctat
     5821 actcatagat aatacaatta taatgaaccc ctttttattt ctaaagatgt ttttcgcaga
     5881 tatagatttt gttactgaca tatttaaagt taattttgat attaaataat taactttggt
     5941 tacattttta tcagctccaa aagtttttct gatagcatca ataggagaaa ttcttcttat
     6001 ttttaagtat gtaaagaaac ttataattag tattattagt attgtacatg caattgataa
     6061 gagaattatt ttatctggaa taacaaaagg tgtaacattt atatttcctt caaattgaat
     6121 atttcctaca gacctattaa atatttgtgc acctcccata cctatacata tacctatagg
     6181 cattgctatt agagcaagta tgaaaagttc ataaagcata agtttgaaaa tcctaaagtt
     6241 ggtggaacca atagctctta agacgccata ttcctgtact ctttggtata ttgatataac
     6301 atagatacta tatattacaa taccagcaaa tagactcata gcaattgcaa cgtatttact
     6361 tgaattatct aaagtaccgt ttttcatagt agattctata agcattgagt ttcttcctat
     6421 acttttctca tctaacatag cattttttat tatattgtct atgtttgtat ttatatcact
     6481 gccttcatta aattcaatat aagttgtaaa atcattcagt tctgattcat tgagattaga
     6541 aaaaatttca cattgtccct tttttttctc tataaatcta tcttcaagga ttccaacaac
     6601 tttaaaagtt tctggatttt ctttttgata taatttaaaa gtaaggtttt gatttatctc
     6661 tggttttaag cccatactat ttaaaatcca tttctcgact accacctcat tgctagcttt
     6721 tggaaatcga ccttttataa gtttagaatg actagtcaaa taatttttat ttgtatatag
     6781 tatgtttata ggtaattttt cattaacatc tgtagacgca tagtaagatg ttatacccag
     6841 atttttaata tctttgctag attttatgga ctttaattga tttttcttta tatttttaaa
     6901 gtatacatgg tcagttccaa gctctctttt caatctatct acatctgctt gctgagcact
     6961 tcttgagaga gtaccaatac caacaacgag tgatgtagca agaattatac tcacaacaat
     7021 tgctaaagac ctagctttat aactttttat ataccttagt actattttca aattatcttt
     7081 catatttacc acttcctttc ttaactaaat caattatata tttatctaaa atatatagca
     7141 aagtaagtat tttcaaattt taagtagtta attgtacaaa ttcatctgta tttttacaag
     7201 tttaattaat atatatgtaa attttaactt tttacataat ttttttaaaa tgatataatc
     7261 cctatataaa ttgtagaggg gaggggaatc atggataaca attttgtatt tcctatagta
     7321 atactaactt tgtttatatt tagcaatctt ataatgaata agtataaatt ttacaaagaa
     7381 ttagacatat taaaaagagg catattaaca ttttttatat cgtgttttgc attgatttta
     7441 tttatggagg gcactaaata tatacaatta aggttaggat atagtttttt acttgaagga
     7501 gtattaaata ttatactttt tttggtttta attattttaa gtttttatac aggctttaaa
     7561 gttataagat tgataaataa taataatgaa caggaatata aattacaaaa actagatagt
     7621 aaaataaatc ataaggataa tataattatc aaattaagaa gtcaaaaaca tgactatttg
     7681 aaacatttgc aagtagtgta ttctctatta aatactgggc tagatgaaga tgccaaagaa
     7741 tatataatga atatatcaaa tagctttaaa tcaaaaaatt caaggtatgg aaaagtatct
     7801 tatttagatg ctatagcttc attaaaatac gaggaatgtc ttgaaaagga tatatctttt
     7861 gatgtctaca ttcaagattt tatggataat ttagagattg aacctaatga tatgagttca
     7921 gtactattaa acataataga taatgcaata gagtctttgt ctactataaa aaaagaaaag
     7981 aagtatataa gattacatgc atatgaagat gaatttcagt atattatagc tataaaaaat
     8041 aatggtccta aaatacataa tgttgaaagt atattttgga atggatttag tactaaagaa
     8101 ggacaagata ggggatatgg gctacattta gttaaaaata tattagataa gtatgattat
     8161 agtatacttg taaatagtga tgatttttta actgaatttg taatcttaat cccaaaatat
     8221 tattagttag gaggagaaaa gtctatgata aaagttttga tttgtgatga tgataagatt
     8281 gtaagagatg atatagcaaa tatagctaaa gagtctggat atgtagatta tgttaaaaaa
     8341 gttaaggatg gtatagaggc aattgaattt ataaaaaatg agaaaataga tttattgatt
     8401 attgacattg atatgccata taaaaatggg attgattctg ctgaagaaat tctttctata
     8461 gataaggata tacatatagt atttgtgacg ggtttcgctg attatagtct tgaaagcttt
     8521 aaagtgcatc ctatagattt tgtagttaaa ccatttaaaa aagaaaaaat acttgattca
     8581 attaacatag caatagacca tattaactcc cataagattg ctaataataa ttttatagaa
     8641 gacacccttt ttgtatataa aataaggaag cagatacata tgattaattt tgatgatata
     8701 gttatgtttg agaaaaattc aagagcaatt aatctacaca ctaaagatga agatataata
     8761 aagttttatg agaactttga tgatttaaaa aaacgcctac ctcctaattt ctttatgacc
     8821 catagacaat acatagtaaa tctaagattt atacataagg ttatacctat aaataaatct
     8881 tcattagaga taaggtttat aaattttcaa gaaaatgcca tattaaacaa atctctagaa
     8941 aaagattttt tatatagatt ttatagggtt aaaagattct agtgaagata gaagaaaaat
     9001 actttttgtg tgatataata agtaccgtaa agataatgta taagagaagt ttatataaaa
     9061 attatttgta attatgattt aatctatata aattacagta tagtatatat tggactttct
     9121 aattttttta agaaagtcca atatatttta gagatagttt ttatacttat aaattactta
     9181 agatactagg gtctttaatc ttactatctt cagcaagtaa tagtatctta gacataatct
     9241 cagcagtttt agggtcttca tcagcgaatg gaaggaatat cttacctcta ctttgagaat
     9301 gtataggaag tatattcaaa gcacccatcc cttttttatg tacaatacca gaacccatat
     9361 gcacagaata ctcacctaaa ttacctgcta taagagcatg agagccttca aaattgacat
     9421 tgttaatttt taataataat aaaagttctt tagcaattgc tatacgcatc tctacagtag
     9481 aatggctagt ttcagggtca acaccaccag catgagcgac acttacaaca aggtctatat
     9541 cacgcataac ttctgagaat agaattggag gtatagaagc taattctaaa cttttataag
     9601 tttttctatc aaaaaattct actgtttcaa tagtaggagg ctctatatct gctggtgaaa
     9661 accaatctgc aagtgcaaac atctttgcca ctatattttc tttataaaat actttctgta
     9721 atccctcttc ataatcgaca gtccaaagct gatttctaag aagtgctaca gttttctttg
     9781 gctgaatttg gtgaccagca tatctgcgag atatagtttt ttcagataat tcatcactgt
     9841 ttattctata atactcacgg aatacttgct taaatggttg aacaatttgc ttactaaata
     9901 aatcatgttg gaactcactc cacttaccag attcaaacaa atgaactgga tgtgcaagtt
     9961 ttaatttatt ttttgccgtc aacttataag tttcaccttc tatattgcaa ataaagaact
    10021 tagacttatc attataaaca tatccaatat tatcatcaca tacccatact agatttttaa
    10081 tcaaagggca gataactgga tttttataga tattggcaat ttctttaact gtaaatacta
    10141 tttcattttt catagcttgt tctaaactct gttttgcacg agaatactga ctctttaaat
    10201 ctttttggac agatttaagt tcaagtacat atggatgttt agcaatagct tttggtatac
    10261 tctttaaaga cttgttgcct ttttgaactt tagtagatgc ttttccgttt tcatcaacat
    10321 ctatccaaat tgaagtacca tcaatatctt ttggtttaaa tagatgagca acttcattta
    10381 gtttttcagt ctcaagagcc cacatcatac gatttacatc tccaaatcca gcacttctag
    10441 ctagattttc tagcgctata gtacaagctt ttgattcact ttcacgacgt tgtgcaccaa
    10501 attgcttgct ttctttagca aacttttgaa taaattcata acggaaagtt gcttctttta
    10561 ggtctccttt tttcatagga agtaaagaga aacttctcaa tttatcttga tttctatttg
    10621 tttcaatttc tttcatcaac atgtctttat caagcttacc aagtgtagca tcagcataga
    10681 gttgtgcacg tctatgagag ttaccaccac tagttatata tttagctgac ttgtaaagta
    10741 tattgaatct ttcttcccca atagttttat atgaatctaa aaaccaatct acatcaaatg
    10801 caccatcaat gaaactacgt ggtgaaatag gggagaatag agcaacctct gattcttttt
    10861 gtgcagagaa gccttcattt atatgtgcat ggaagtacca aattgtactt ttcagaccct
    10921 tccagtttaa atatttttca attatgttta cccattgagg ggcatacata gcagattcta
    10981 tcaatcttaa ctcagtaatg tcggtatttt taagtaaact ttttaatttt tttgaatcat
    11041 cttctttagt aggatagcaa tttttaagta gagaacttaa aacatctttt tttgaataat
    11101 tgctaccata tgaatatcct ctctggaaag tttctttacc aagagcgacc aaaatattta
    11161 caaaataatt tataccttca aagtattgta tattattagc tagattagac acttctgttg
    11221 gcatatcacc tctacgtgat tcaatttcta taattcggtt tgtaacagtt tttaaattat
    11281 ctttaagcca agggtacttt tctaatgtgt cgccagccca tctaggattt gtcaatgttc
    11341 ttattatatt tgatgcgttg tatccactta tcatttctct attaacttgc tcttcagtca
    11401 ttaatcctaa ttcatgtgca cgagcaaaca catttatgct agtatagaaa ggaaacttat
    11461 attctagcaa ctgataattt gaaaacgtag tgtagaaaaa cttagtaaaa gaaatatcat
    11521 cataaataaa cgaatgtgct ttatcaagcc aatagtttaa aataggggca tttaaagcag
    11581 ggcagtattc attttgtctg taatagtttt tagtaaattc aactctttgt tttttacatt
    11641 gttctatagt caataagttt ctaagtttat agtatatttc taaacaatag ttaaatattt
    11701 ctttatggtc aaactcattt agtaaaactc ttaaaagttt tcttgtaagt ccattaaatt
    11761 taagtttttc aagttttgta tatattttat tttgtttttt agagtcaagg acatttgaat
    11821 atatagatga aaaccaactt ttttctgttt cattatatcc acatgtactt atactataaa
    11881 ataagatatc aagtattaat ttgtaatcta agtcaagttt tttactagtt tctctccaaa
    11941 gctctgctaa tggataatta tcaagagtat cattagaaac tttatattta ataggagtca
    12001 agttataagt agaataacct aaaagtactt tgtctacatt acctgaccat ctttcaactt
    12061 catattcata atctgcattt tcagtaataa gttcatcaaa tttttcataa acttttatta
    12121 ttttatttat atccgtatcg agaatttttt ttgcttcttt ttttgttgct acagaaacag
    12181 aatcctcacg agtagataaa cttatatttg agataatttt attaagcttt gatgagctat
    12241 tagaatcatc tttaaaatca aattgttctg gaatttgaac tttgttttca gggttatata
    12301 ttccaaaacc attttctttg cagtaatcat tttttgcttt acctaacaaa ttatcaatta
    12361 gtatttgaac ttgagatgta ttctttttag atttatcaat atcctctata agtaaaataa
    12421 gcttattata tagttcttgt ctagcagtat tgtcttttaa taagtttaca atttcaagac
    12481 ctccaaggca tttttgagaa tttgaagatt ttatcagtga agaagcaata ttttccaaat
    12541 ttgaatcatc ttgttcaagt aaaattttta ttactgtttg tctaatagag cttgtcttta
    12601 aagacaatag attggttatc ttatctaatt ctacatctgt tagctcaagc tttctaagta
    12661 gactcaatac cgtttctcta ttggaaacac tcttatcact taaacattcc aataaaaatt
    12721 cacgttgtct atctgtcttt ggttcattta caaaattgac tataagtgaa gctcttaaat
    12781 ctgaactcat aagatgacaa ttttccataa gcacatctat aaattgagca ttcatatcgt
    12841 atgctgttaa agtcatcata catttaagta tttcatgaga agaaatttca atccaagtcc
    12901 atggaaatac acttcctgaa aatgattttg tctttgaatt taaaatttct aaagtatgtt
    12961 ttaaactttc aaattgttct tttctagcat caaagtcttt gtcaatagga gtgtttgaca
    13021 agtcaaaatt agtttctctg ttttgccaac tatagtagta gccaacagaa ccttctacat
    13081 agaaatttgt aattacccat gctagtatct ctaaatcatc acccttaatg tttttagatg
    13141 ctatagaatg tttaaaatat gtactttctg tatgcgataa aaagtaaaga gctacaagtt
    13201 ttttatattt ttcctgacaa gaaagtaagt tttcaataag agagtaagag tcatatatgt
    13261 tgtaagttgc agtagcccat aaggcaaaat aaatttcaag attatcattg ctattaattg
    13321 attctatacg gaacttttca tcagtcaatg atttatatga aagttctaaa catttacgta
    13381 ttattccagg tttttggtct gaaaaaccaa gtcctgtcca tgtatccaag gctcttataa
    13441 cagaactaaa tcgctctaaa ttgttgtcca aaatagtttt taacatgtat attgatgcag
    13501 aaattgtacc ctcatctaaa ctctctacaa tttgctgtct aagtccttct tgttgtttgg
    13561 ctgccaaaag aagtttagaa agcatttcat agcatttatc actatgactc ttcatgatac
    13621 caattatcat ttgtcttgta agtagagcag tttgattttc tccaaatatt acttcttcta
    13681 aagcacttat tactttttga tttcctttgt ctatttctag tgctatttta tcactcatta
    13741 tagagtcata gtacaagacc ttatttggaa gagtaagata atctataact gaaaaatcat
    13801 aataaattaa atcaacatag tttgaaataa accttataat acctctaaaa taatccacaa
    13861 gtttatttga gcgataccct ttacgataat atcctcctga atatgtataa tccatctttc
    13921 ttttaattaa ttggcaaagt tcttctactt gttcagaagt aaatattaat tctaatgcat
    13981 tttttaaagg tccagaaagg agctcgtcca tatttttaat ttcgtagtag tggcaattgt
    14041 agtatttctt tatcatattt aagaatttgt cttcaggttc tctataatag tatgaactat
    14101 tttctatgca gtcccaaaga gactttgcta agtcgtagta ctgttttgaa gaagatttag
    14161 taaaattatt tttaaaattt tcaattattt taggattttt ttctactcta gtacgttcta
    14221 acatttatgt acctccaaat tatttatttt aaaacattct tccagcaagc aaggtaagtc
    14281 ttataaaagt aaatatatct ccacttttca gatttataga ggaatcgagt ttttcaataa
    14341 catcctcatt tataagcact ttgtagattc catcttcaaa tgcctgtaac gctacctcta
    14401 ttgccttttc tacagattgt ttattctcat tgtaaataga gccaaatcca acttttccaa
    14461 tatcagcttg agattcaatt tcttcattag ttaagaagtt tattattgat ttttctggga
    14521 ttttctcatt atattcaaga acatttttag atacaatttc agagatagct tcttttaggc
    14581 aattgatgtt gtcagataca tcaaaagggg taagttctag cataggtttg cgtttgccaa
    14641 cagccttaac tctaaaataa atttgcataa aatcacctcg caaaatatta attatgtatt
    14701 tagaaattta aaaatttatc tatttgttat attatatcat tttgtgaatt attaatgtga
    14761 attatggaat tattttacaa aaaatagaaa aaaagctatc ttaaagtcta aaaaagcaat
    14821 aaaagataac ttttaactat aattatatag aattataact gtacatttat taaattttaa
    14881 ttttagaatt atttttgata actatctttt tttatttata aattttgctc ctaaatattt
    14941 tttgatatct tcttcaggag aaaagtcatc aataagtatt tctttcccag tgtcttcaaa
    15001 tactacaaga acttcacagt caccttgtaa gaaaaatttt ctaactgtat cttctttaac
    15061 ttctctaact tttattacat tctttttttc tttttcaaag tcttttgtgt aataacttcc
    15121 catcatatta attatttttg tatatctatt cataaaatac ctccatatgc gattaaattt
    15181 aaaaaatatg ttataataat tgtttgtatt aacttaataa ttataacaag gagtaataat
    15241 aatgactagt ataaaaaata aagatatttt aaattgtata gattattcca ttaaaaataa
    15301 gctctttgac aaactaaatg atgtatataa gtccttgcca gtaggaaatt gttctggatg
    15361 tggaaattgt tgtatggagt cagtaggtat aaatttaatt gagttcttga atatattttg
    15421 ttatcttgaa gatagagttg atttaaaaaa aagctgtata agtaaaatat tagattatta
    15481 ttttgaggag tatacaagaa agaacccatg tccatttaaa gatactaata atagatgttt
    15541 aatatatgaa gttagaccat taaattgtag gatgtttgga cattggaaaa aagaggatta
    15601 taataaaaat ttagataatg ttattgagaa aaataataac tatagagagt taatgaaaaa
    15661 gcaatatgga tttgaaataa atgatgaagt agtaaattac aggatagatt attgtgatag
    15721 atttattcca aataaagatt atttaagtaa atctaagaga ttaagctttt ttgatgagct
    15781 tatgatatta gactcaaata tttattcaag tggaaatata gatatagact ttagggatag
    15841 aggtatagtt gaatatttta tagagtcatt actttataga aatttagcat ataatgtgaa
    15901 aataaggata tctaaagaat acaaaataag aaaaagaact atagatagaa taaaaaggat
    15961 tgttcttgta tagttttata ttagtaagta ataaattgta tcataaatat tgtcaaaatg
    16021 aggtgaagaa ggtgaatctt acaaaagtaa aaggaaatac cttttttata aaaggtggca
    16081 cgaatacagg aatatatgta tttgaagata acacagcact tatgatagac ccagggttat
    16141 gtggttcaag acctaggaga gtaaataaag tattagatga aaataatata caggttagat
    16201 atattataaa tactcatggt catgatgacc actatggagc ttgtaatcaa tttaaagaat
    16261 attataaaga tgtgtgtata atgtcatctg aatacgataa attatatata gaaaatccag
    16321 aattgttttc aaagtatatt gttgggggaa agagcaatgt atttatggat aatatcttaa
    16381 aaaataaaat gttggatgat ataaaaatag ataaatctat agaagctgga aaaattgaat
    16441 taaacaatga aatgtttgat ataattgaat ttcagggtca tacacctggt agtatagctg
    16501 ttttgacgaa ggataatgtg atttttgttg gcgatttatt gataggagat gaaattctat
    16561 caaaatacga tttcttgttt ctatatgata tacaagaaca aataaattca ttagaaaaat
    16621 taaaaaatat agattttgag tacttagttt tagggcatgg caagcaagtt atatcgaaag
    16681 aagattctta taaattaata gaaaaacatt tgaatgcttt aaaaaaatat ttatatcaaa
    16741 taagagagtt gcttgtagaa ccgaaatctt tagaaatttt attaaaaaac attataaata
    16801 acaataattt aagcaataat tataaagagt atcatttttt taaatcttcg ttagtatctg
    16861 tcataagtta cttagttgat ttagaagaaa tagggtatat attggaaaat ggagaattgc
    16921 tttactatac aaaaacaaaa taaattatga taaaataaag aaggtcataa aaaacaaata
    16981 aagggtgagc aatatggaat acgaaaaatg gaatgagata ctagcacctt atgaacatgc
    17041 agtagaggaa ttgaaaataa aatttaaaaa tataagaaaa gaatatttag caaaaggtga
    17101 atattctccc atagagtttg tcacaggtag aacaaaaaaa atatcttcca taatatctaa
    17161 gttaaaaagg ataaatgcaa aagatataga aactgaaatt gatgatattg ctggtataag
    17221 aataatgtgc cagtttgttg aggatatata tgctatagtt gatttgataa aagtaagaaa
    17281 tgatatgact ataataggag aaaaagatta tattacaaat tacaaagata gtggttatag
    17341 aagctatcat gttataataa aataccctat aaactccatt gcgggttcaa aggaaattat
    17401 atgtgaaata caaataagaa ctcttgcaat gaatttctgg gctacaatag aacattcatt
    17461 aaaatataaa tatgaccatt acatacctga gactcttgct gaaaggctta gaagagcatc
    17521 tgatgctgcc tttcttttag accaagaaat gagtgaaata agagaggaca taatgaaagc
    17581 tcaggctatg taccaaatga agtctatagc tattagagat actttaaata gaatacaaga
    17641 gttatatgac ttgggtgata cacataaagc tatgcagtac caaagaaaac ttgatagaac
    17701 tgaaacagat aaaaatataa ctgaaatttt ggaattaaaa caagaaatag atatattatt
    17761 agagcaatat aaggatacta aggtagatga taaagtagtt cagtaaaaac tacttgtaga
    17821 aaatttgcta aatattaatg gggctgcctc ttaatggaaa ataatttcta aaaagagaca
    17881 gcctatttag tgtaattaag aaaggaatga tattatgagt ttgtatgcta taggtgattt
    17941 acatttttca acatcagtca ataagccaat gaatatcttt ggaagtaatt gggatggtca
    18001 tgaaaagaaa attatagata attggaaaga agttgttaag gaagaagata tggtcttagt
    18061 actaggagat acatcttggg gaattaattt atccgaagct aaaaaagatt tagatataat
    18121 aagcaaactt ccaggtcaga aaatacttat aaagggaaat catgattact ggtggacaac
    18181 cgttacaagt ttaaataagc tatatgaaga catgcgtttt attcagacaa atttttatga
    18241 atataaagat tatgcaattt gtggaggtag gggctggata tgtcctaatg atgttaaatt
    18301 tgatgagact gatgaaaaag tttataaaag agaagaacat agacttagac tatcattaga
    18361 atctgctcgt aaaagtggtc actcaaaaat aattgtgatt actcattatc ctcctacgaa
    18421 tgataaattg gaagaatctt tatttacaaa gttatttgaa gaatataatg ttgaaaaggt
    18481 gatttatggt cacttgcatg gtaaagaatc ttttaaaatg ggattgaagg ggattcgaaa
    18541 tggagtagaa tatacattag catcttgtga ctatacagaa tttaatttaa taaaagttca
    18601 cgattaaaaa acataaattg gtaaatacta taagatacat gattaaaaat aaatatttga
    18661 gggatttcgg ttttgagaaa ggagacacga cttatgaggt ggatattagt ttttatattt
    18721 ttatatctta ttcctttagt agtgatattc agaaattaca agaattttaa gaggtcttgt
    18781 atctacagta gtatttatgt ggtattagct acaacaataa tgataagtaa tatttatatg
    18841 agtggactta ataaaataaa agagtctatg tattatcaca attatatttc tgatgagaca
    18901 tatgatgaaa agtatgtatc aaattttaag gaaaaagaaa gtactgattt aaaacaggat
    18961 aataaaaaga atgaagaaat atcaaataat aaaaatttaa acaacaaaca agatagaaat
    19021 atacaaaata aagaaagtaa tgaagaagga agtaatgata taaaagaaaa gaataattct
    19081 gatagtaatg tttcagtgaa taataaatca gaaaaacaag aagataatac aaaagaaaat
    19141 aataaatata caagtaaaga aaaaaatagt gaagatataa aaaaaataga tatggaaagt
    19201 ataggaattt ttaagaaaga aatttataat atagaaagag cagctttagt tccaatgaga
    19261 gaatgtatac cttacactaa ggatatagca aaaaatataa ctaaattatc tagtataaaa
    19321 aaagatgtta caaatgccag aaacaagtgt aaagaagttg taaaagaata tgaaaatatg
    19381 cagattccag aactttctaa ggagaagtat acagaaacat tgagtaatgc tagagatgac
    19441 gtaaagaaag catatgagct tagagaaaaa tctatggaaa gtgctttgaa attaataaat
    19501 actaaaagcc ctaaatatat agggaagata acagaatatc ttgatttatc agataagcag
    19561 atagaaagtt ttaaaaatag attgaacgat ttaaaagaag aaataaataa ttcagaaaca
    19621 aataatatta attaataaga tttaaagata taagttaaaa gggagattat gatgaataaa
    19681 cagagtatag gaaaactaaa tatgtttttt atggggatta ctcaaagaaa ccttgataat
    19741 agggattttt ttattgagtt agaggtgatt tttaaatctg gaagaaaaga gtttaaagga
    19801 attgcaatag aggaagataa taaatataaa tttaatttta aaggaaaatc agatttatat
    19861 acgtttaatg agttgcttaa gaatatttct aaagaggcag aaaattatga tggattagta
    19921 tttaaatatg ttgagcgagg aactattgtt gtaattgaag gagacaataa gaaggtaaat
    19981 gtaaaatatt tagataataa ggaagaagta cctaaaatag atgaatttac ggcatctcaa
    20041 ataaaaaaca gagattatta tgtaaaagta ggacaagcaa atgcactttt aaaagaaatt
    20101 ggagtactta caaaagatgg taagataaaa aatgataaaa taagaaaata caatcagata
    20161 gaccattttg ttgaattgat agatagtatt ttaaaagaaa taaaggataa agactgtata
    20221 actatcttgg attgtgcttg tggaaaatct tacttaagct ttgtcttaaa tttttatata
    20281 aaagaagtat tgaagaaaaa ctgttatttt ataggaatag attattcaga tgtagttata
    20341 gaagcatcaa aaaatatggc taaaaacttg ggttataaaa atatgtcatt tataaaagag
    20401 gatttgacta attatacacc taatagggat gttgaccttg taataagtct acatgcttgt
    20461 gatacagcta cagatatggc aataggtcta ggaattagag caaaatctga agctatagta
    20521 gtagtaccat gttgtcataa ggagttatta gggcaatata gatatgaagc tatggaacca
    20581 atattaaaac atggtgtatt taaagctaga tttgcagatt taataactga tggtttaaga
    20641 acattgttat tggagggcaa tggatatgat acttctgtag tagaatacat atctccactt
    20701 gatacaccaa aaaatttaat gataagagcg ataaaaacta aaacgaataa tgacaaagca
    20761 ttaaaagaat ataaagaact gaaatcacaa tttggagtgg aaccaacctt agaaaaactt
    20821 atatattagt taaaaatgta aaatttacga aaagcttgct taaatatgca agctttttgg
    20881 tattatatag gtatagtcat atccagagtt ttgatttata attaaagctg tgctataata
    20941 tttgattaat caaatcaata aatgttacat ggaggtaaaa atgaacaaat tgaatatatg
    21001 tattgatata gatggaacaa taacaagccc ttatcatttt cttccatacc taaatgatat
    21061 ctttaataaa aatataactg aagcagagtg tataacacat aattgggaag aattgtatgg
    21121 ttcgggaata agagatgtgt atgcggagtt taataataag tatatacact catatgatga
    21181 agcaaagatt gtagagggtg ctacagaggt aattagcaca ttatctaaag gacataattt
    21241 atcttttgta acggctagac atgagtgttt aactgatgta actaaaaatt ggctatcgag
    21301 acaaggattt tcagatatag atgtttactt attaggaagt gattataaag ttgaaaaggc
    21361 aagagaactg agttgtgaca tatttataga agataatcct ttaaactcag tgcaactagc
    21421 tgatgatggt gttaaagtaa tacttctgga tactaactat aataaagatg ttaaacatca
    21481 aaatatagtt agagttagta attggataga tattgaaaag attataaaac aaggtattta
    21541 aagatttgta gattgaaagg gggagcatat gatagattta aaaattgaaa atagaaaagg
    21601 aaaaatccat gtaaagagca gtgaaataaa agacatttta gaattacgtc cagacttcga
    21661 atatgtacaa gatatatcaa atactataaa tcaagaaaat atattggtat ttgattgcca
    21721 gttgacagga aattcttttg atatggatga tttagatata gaagaaatat tggaagagtt
    21781 aggtgaagaa atagatgagt cttatttcag tgttttattt gaagatgtaa gagcgtattt
    21841 aaaagatgct actgatgaga tagaagcaga cttacaggat aattacttat ttgataattt
    21901 gagatgttat tttgatatat acaatataaa tcaagaattt acagatttta agtttgtatt
    21961 tttagtttct tttaaagata taaaaatttc ttcattagca aacctagcta agattgtttc
    22021 taagagacag cttataggtg catctaagtt ttatagttaa aatgaaatat tattataata
    22081 aaagctagta accttgtaaa aatataggtt actagttttt tatttattca ttttcacaaa
    22141 atttcagaaa actatttaca ttctaaaaaa agtaatgtat attaaacata atgtacatta
    22201 taatggataa aaagtttcta ttaaattact aagtttattt aataatcaaa ataatttatc
    22261 ttatattagt atgtattagg gggtatttat gcaaagttta aatgaaataa ttgctgaaaa
    22321 tttaaaaaag ataaggaaag aaaaacatct tagtttagac aagattgcac aacttagtgg
    22381 tgtaagtaag agtatgctat ctcaaattga aaagtgtgag gtaaatccta ctatatctac
    22441 tttgaagaaa ataactaatg ggctaaaaat ttcatttaca tcattgatgg agaggcagga
    22501 aagtgacata gaattgattc aaaaaagtga tatagaccat tttattgaag ataatggaaa
    22561 gtatataagt tatccaatat ttccatttga ctccaaaaga agatttgaga tatttatgat
    22621 tgaaatagaa gaaggtggaa atttagattc aaatgctgaa cttccaggaa cacaagagtt
    22681 tataactgtt tttagtggcg aagtaaccat taaaataaat ggagaagatt acattgtatc
    22741 tagtggaaat tctataagat ttaaagctga tgtatcacat atatatagaa actcaggcaa
    22801 aggtatagct aaaatgagta tggtagtata ttatatataa ataatttaat ggaattagag
    22861 tgatatttag atgattttag gtatgaagat atattatatt taagttatag gagtgtgatt
    22921 tatggatgaa taataaaaaa gcagtttttt tcttttgcag tgatttaaag aaagacccag
    22981 tagccagtaa tgtgataaaa tgttgtgaag aaataatgga tttaaatcaa actgatattg
    23041 ttattgatga taattttgta ttagagttta aggataaaaa caataactta tttcattttg
    23101 taaaaacaaa agatgtaata agtcataatt ataaatatta tcttccaatt ttaaatagac
    23161 attttagaga ttatgatttt gcaggagttg taaattggca tgagggagaa aatgctccag
    23221 aacatatcct aacagctcat acaattggag atgttccaac aggagaattt ggaaattcaa
    23281 atccaagata ctttaaaaat ctaatcaatg ctattgagga tataaaaaat gaaaatctac
    23341 ttgatgaatt tactacatta acagaagcaa ctcactggtc tggaacaaca tatggtgaag
    23401 aatctaaatt aattacagaa tattctgtac ctatgttgga tattgagata ggaagtagta
    23461 gtgatagttt taataatagt atagcaatac aggtattggc aaaatcatta attagagtat
    23521 ttgattgtga tgaacctttg aagactttgt tatgtgttgg aggggtacat tttgagaaat
    23581 ctttctcaga tattataaaa aataaagaat ataacatatc aattggacat gtattgccaa
    23641 atcaatggat tgtaagtgga atgtatgatg atgaatctgg atttgagaaa ctagaaaagt
    23701 gtataaatag cattgaagga ggaattgatt gtatagtttt tcatgataaa ttaaaaggta
    23761 cctataaaga gcaatgccgt aaactaggtg aaaaacttaa tgtacctgta tttaaacata
    23821 aaatattaaa aaatccaaaa gacttaccta tatggtagtc ttatacagtt aatataacaa
    23881 taagtcggat taatttttaa gcgaggtcaa aaatgatatt atcttatttt gcattattaa
    23941 ttagagtagt gctattagct tttgaaagag tagttgtaag attattaggt gatgaagaag
    24001 gagatattta taaaaatata gcttcatcat ttctattttt ctttataggg ggagtatgtt
    24061 tacttccatt tagcataatg gatagagtta gtgattggtc gtttttaata ccatgttata
    24121 taagtagttt agtctattca attggttcag tagcgtatgt aacgtcttta gcaactgggg
    24181 aagtttcact tgttactcca ataaatagtt taaattcatt gtttttactg cttttatcag
    24241 ttatattttt aggtgaaggt ttaagtttag caaaagttgc aggaatcata attatgattg
    24301 gtggagtgtt tatattaaaa aaagtaagtt cttttttaaa gaatgtctct gtaattttta
    24361 acaatttacc atgtagatta atgtttttat acatattttt gcagtcagta ggaagagtat
    24421 tggataaggc tttttttgta caagtatctc ctatattata ttcaactata ctgtattttt
    24481 tcgtaggttt aaatttattt atctttttag catttaaaaa gaaacaaaaa ataatttgtg
    24541 agatttttac taataaaaag gggctttcaa ttttaagtgg tgctattaat ggatattctt
    24601 atttagcatt attaattgct ttaaataatc tagaacttag tatagcagag ccattttctc
    24661 aagtatctat gataataact ttaatacttg ctcattttat attcaaagaa aatataaaag
    24721 aaaaaatacc aggttcaatt ttgatactaa ttggtgggtg gctactgtta ctttaattga
    24781 cataaaaaat gaattataaa ggtgctatta gttagtatca gaaaatttaa aaaagtattg
    24841 acaattcttt taggcaaatg ttaatataat aatacaaaat agtataaata gaagacatgt
    24901 tactggtaat gcaggcagga tcgaatatat tgctttgatt tttcaaggtg tttatatagg
    24961 ttctgccttt tttgcatctt gaatggccat tcataaaaaa ttatggagaa ggagattaca
    25021 agatgaatta taaaaaaact gccattgaca ttattgaaca agttggtggt tcaaaaaata
    25081 ttttagcttt agaacactgt tcaactagac tacgctttaa gttgattgat agaagtaaag
    25141 tcaatcaaga tgctttaaaa aaagtacaag gtgttatgag tatagttaat ggggcacaat
    25201 ttcaagttgt cattggaaat agtgttgttg atgtgtatga tgaaatttta aaagtttgcc
    25261 ctttagatac aaatgatagt actgtaaaaa ctgaagaaaa aataaactta ggaacaagat
    25321 ttatagaatt tattattaat atttttcaac cactgatttt tgctattgca ggagctggta
    25381 ttttaaaatc actgttgatg ttattagcaa tgtttaatat tttaaaatca gattctacta
    25441 tatatacatt attagttgct atttcagatg caacattcta tttcctacct cttatggtag
    25501 ctgtaactac tgccaatgta ttgaaatgta atcgtttagt agctattgcc gctgtaggat
    25561 acttattgct tccagcaaca acaactgctt taagtgaagg tgttgaacta tttggattta
    25621 caattccaaa cattgcctat aatgcacagg ttttcccggc tatcttatgt gtgtctttct
    25681 tggcaacaat ggagaaaatt tttaacaagt attcaccaaa accaattcga actttctttg
    25741 ttcctatgat gtctttggca attactgttc caattactct aactatttta ggtcctttag
    25801 gatataacgt tggtacaatt tttacaacca ttattttatt cttatataac aaaatgggat
    25861 tcttagttgt aggattactt gctgcttttc ttccatttat ggttgcaaca ggaatgcaca
    25921 aagcactaat accttattca attaatacaa ttggaaagtt gggttatgaa gctttatata
    25981 tgacatcttc attagcccac aatatttctg aaagtggtgc ttgttttgca gtagccttgc
    26041 gaacaaaaga tgaaacatta aaacaaacag cattatctgc aggaatttct gccttgatgg
    26101 gaattacaga gccagcttta tatggtatta ccttacaaca taaaagagca atgttaggtg
    26161 ttgtattctc aagtgcaatt tctggtacct ttttaggatt atttgcagta aaaggatttg
    26221 taattgttgg atcagggctt gccagtatga gtatgtttat tgacccaaac aatggaaaca
    26281 atttgatttt tgcgagtatt ggttttgtta ttgcaatatt aggctcgttt attattacac
    26341 tgattatttg gaaggaagat acaaatacag tagagtcatc aattggagat gttgttgaag
    26401 aagagctaga agaagaaaaa gaagtaaata tcttagtaac tccagtagaa ggaaaagtaa
    26461 tagatttaag taaggttaat gatgaactat ttgcaagtaa gactttggga gatggagttg
    26521 caattatacc aaccaatgga aatttatacg caccttgtga ttcagaagtt gtgatgttat
    26581 ttgaaacaaa acatgcaatt ggtttaagaa caaaaaatgg ggctgagatt ttgattcata
    26641 ttggaataaa tactgtaagt atgaatggag atggatttaa aacatttgtt aagacaggcg
    26701 ataatgtaaa agaaggagat ttattaattc aatttgattt agacaaaatc tcacatgcta
    26761 atttagattc aactgttatg attgtaaaca ataatggagc agattatgct tataaagtgt
    26821 taaaccagtc ttatggcaat gtaaaaaaag gaagtatctt gtttgatgta aagggaggaa
    26881 tataaatatg agaaaatttc cagaaggatt tctttgggga ggagctacag ctgctaatca
    26941 atttgaaggt ggttggaatt taggtgggaa agggtggtct gtatcagatg tagcaaaggc
    27001 acactttgat gcagatgtga aagattataa atctaataat gaaatcacaa caaaagatat
    27061 agaagaagga ttagcacatc ctgaagatga agtaaattat ccaaaacgtc atggtagtga
    27121 tttttatcat cactataaag aagatattgc tctaatggca gaaatgggat ttaagacata
    27181 tcgaatgagt attgcttggt ctcgtatttt tccaaatgga gatgataaag agccaaatga
    27241 agaaggttta cagttttatg atgatgtatt tgatgagttg ataagttatg gaattgaacc
    27301 acttgttact atgtcacatt atgaaccacc attaaatatc gttttaaact atgatggatg
    27361 gtattcacga caagttatca atatgtttgt taggtatgta gaaactatct gtgaaagata
    27421 taaaaacaaa gtgaaatatt ggcttacatt taatgaagtt gattctatga ttcgtcatcc
    27481 gtacactact ggtggtttag ttcgagaccg ttttaaggat aaaaactttg aggaagttat
    27541 ttttcaagct atgcatcatc aatttgtagc tagtgccatt gcaacaaaaa tttgccatga
    27601 gattattcca aattcaaaag tagggtgtat gttaacaaaa ttaacgtatt atccatatac
    27661 atgtagacca gaagatgttt tggcaactca acaaaaaatg agaagtattt atgcatatag
    27721 tgatacgcag gtttttggtg agtatccagt atatttactg tcgtatttta aaaataataa
    27781 cattcaaata gtaaaagaag aacatgatga tgaaattatg aaaaagtatc cagtagattt
    27841 tatttcattc tcttactata tgtcttcttg tgaggcagct gatacaactg gattagatat
    27901 tacacctggg aatacgttat tagctgtaaa aaatccttat ttagaaatga gtgaatgggg
    27961 ttggcaaatt gattcaatag gtctacgtat atctttgatt gaattatatg atagatacag
    28021 aaagccttta tttatagttg aaaatggatt gggagctaaa gatattttaa ctgaagataa
    28081 aaaagttcat gaccaatata gaattaatta tttaaaagaa cactttaaat gtatgttaga
    28141 tgcgattatc gaagatggcg ttgaactttg gggatatact tcatggggtt gtattgattt
    28201 ggtcagtgaa tcaacgaaac aaatgtcaaa acgttatgga tatatttatg tggatgctga
    28261 tgactatgga aaggggacat ataatcgata taagaaagat agtttttatt ggtataaaaa
    28321 ggtaattgaa aataatagta tagattttaa atgaccaata gaaggtgagc aaataaaatg
    28381 aactacataa taaagaaagt tttgaactcg agcgttgttt tagttcatga tgcaaagtat
    28441 aatgaattta ttttgctagg gaaaggaatt ggatatggta aaaaaacagg agaatatatt
    28501 tgtggttcca atgataatca aatgtttgtc cctgttgaaa atacaaaatc aaaacaattt
    28561 ttagaattaa tggatgatat tcctgtcgac attttaaaga taacacagga aataatagta
    28621 gaggcagaaa agttattgaa ctcatctttt aataaaaact tatacttaat attagcagac
    28681 cattttaact ttgcaattga aaggatgcgt aaaggaataa aaattacaaa tcgagtattt
    28741 tgggaaataa aaaattatta tccaaatgag tttaaggttg gaatggttgc aatttatatg
    28801 gtagaggaga gattgggcat tcaattacca gaggaagaag cagctaacat tgctttccat
    28861 tttgcaaatg ctatggcttc agatggaaat tcatatgata cgattaagta tgccaaagta
    28921 attggagaaa taattaatat ttttgttttt tctttgaata gaaccttaga taaaaagagt
    28981 atgcattata tgagatttat aacacatata aaattttttg tggaaagatt tttttcagat
    29041 agtatgttaa gcagtggtga tgatttatta tttaatcaaa tgaaaaggtc aaatccaaaa
    29101 gaaatgttaa ttgcattaaa agttagagat tttttagaaa agaaatatgg aaaaaagtta
    29161 acaaatgagg aaatagcttt cttggttgta catatcgcac gagttaagca atagagtgaa
    29221 ttactaatat tatcttatac gtctacatgg tagaaaattg aaagaaggta aagtatataa
    29281 agaaactgag acatattatt ttgttgttca ttatgtttat tttatgagtg tatcctgtta
    29341 aaaatttaag ttaatattta taattaaaat atacaaatag ttaaaataag tttatgtggt
    29401 tatgaattta ttttaactat ttttttgttt aatggaaaat atgttttata actagaattt
    29461 tatttttaat taattataat acaaaaaact ttataaaatc ttcagaattt cttaaagaat
    29521 atgtaagtaa cataagatat attatattta gttggtaata taaagggggc aatatttatg
    29581 aagaataaaa aattcaatgt tataacactg ataatacttg ataatcatat ttatgccatt
    29641 aataaagagc agattagtac taattcaaaa agaatttact ttgaaaaaag tcgatttttc
    29701 agtgattata agtgaataaa tatatataaa catttaataa atttagaagt taaatgtttt
    29761 aatacgaaag gatacacata tgataaattt agaagaaaag tatttaacac gaaaagacac
    29821 atatatgata aaaattctag aatacaatgg gcatattcga aactggaaag ttctttgtga
    29881 agaacttgga atcgattctt cattatgtag agatgagcgt gaacgagcaa ttttagtgga
    29941 agcatataag acatggggat atgatatggc aaatcacatg catggaatgt ttgcttttgc
    30001 attatgggat actgtggaaa agaaactctt ctgcctaaga gaccagtttg gggtaaaacc
    30061 tttctattat tatgagactg aaaatgggaa gcttctctat ggttcatcta ttcgtaagat
    30121 tatggagcaa ccaggatttg tgaaagagtt aaatgaagac atgttacaga tttatatgtc
    30181 tttcacatat gtagcaggtg aaaatacatt cttccgtgga gtaaagaagc ttatgccagg
    30241 acattacctt gtctatcaga ataaaacagt atgtattggt cgttattgga aacctgaatt
    30301 tcatcctgac cacagcaagt ctattgagga atggacggat gaaattcata caacacttca
    30361 gaaaattatg ccagaggtaa aatcagagaa tgaaactgca gagttattcc tatcaggagg
    30421 tgttgattca tcttatatat tggcaatgtc agatatagaa aaaacaggtt catgtggtta
    30481 tgaggaagag cgttttgatg aatcaaaatt agcacaacag acagctaata ttcttgggtg
    30541 taaaaattcg agatatataa ttacacctga agagtatttt gcgtcagtac cttatgtaat
    30601 gtaccatatg gagcaaccaa ctggagatgc atctgctatc gtttttgcta ttggatgcaa
    30661 ggcagcagct gaaaacacaa atatctgtta ctctggagaa ggagcagatg agttttttgg
    30721 tggatataat atataccata aggcagagtg ttatggagag aatttgaaga cattttatat
    30781 tggaaataca aacattatga atgagggtga gaaaagaaaa attcttaaga aatacaatcc
    30841 tgatgtgctt cctattgaag tggtaaaagg aatttatgaa gaaacagaag aactagatac
    30901 acttactaac atgtcaaatg tagatattca aatatggttg gaaggagata tttattttaa
    30961 tatagataaa atgagtactg cagtaggatt ggaagtcaga atgcctctta cagatacaag
    31021 aatatttgat attgcatcca gaataccatc agaatataaa gtgaaaggaa aagagaataa
    31081 aattgccttt cgtacagctg catcaaaaac attaccagaa gagattgctt ttagaaataa
    31141 attaggattt attgtgccaa ttcgtatatg gatggctgat gaccgatata ataaggatat
    31201 ccgagataaa ttcaatagtg agatagcaga taaattcttt aacatagatg agattaatga
    31261 gatttttaat gactacatta gtggaaactc tgataattgg agaaagattt ggatgattta
    31321 cacattccta gtgtggtatg aaatctattt tgtaaaatgt taatacaaga ggaagaatca
    31381 cctgaaatac cattcaggtg attcttaatg ttttataatt ttacttgcta attcttatgt
    31441 ctaactctta atggtatatc aagttttttt gccagttgtt tagattcttc tatttcttct
    31501 ggagatattt catctactac tgaaaaagct acttctttta tatatttttt gcaatctctt
    31561 gcaaaatcta acatataatc aaatgatttt tctccaaact ttggttgagt aactctatta
    31621 taagcttctt tatttggggc attaagactt attgatactg catctataac attttttaac
    31681 agaatagctg tttttttgtt atgtattaaa tcacttagac catttgtatt tattcttatc
    31741 tttatgctac ttttttcttt tataaacttt gctatctcta tcaattcatt tattctcatt
    31801 aatggttcgc catatccaca aaatacgatt tcatcatagt cgtctaaatt gtatttattg
    31861 aaggcttctt ttacttcatc tacacttggc tcatgctcca accataaact accactattt
    31921 gcaacttcat ctttttcgtt tcttatacaa aaaacacaac tacatggaca tgtattagtt
    31981 atatttacat agatactatt ttcaattgta tataagatat tcataatttt ccctccataa
    32041 atttaaattc ttaattaaaa taacgttttt taaaatcaag tttatcaagt gccataccta
    32101 agattataaa aacaataaaa cttcctattg gctgtaataa gccaagtaag ctcattacaa
    32161 atgcacttgt aaaacttcca ataattatac cttcagcaaa catgtataaa actaatccta
    32221 ctatacctgc tacaaccgaa gcaactatat ttctcttatt tattatcttg tcacttttag
    32281 aagtgaaaaa taatacaagt attggtttta tgattatagt tggtattacc cagatagcag
    32341 cacctgtaga taaatcagct agaccagcac caattgcaga agcagctata gcatagtttg
    32401 ttggcaaaat agttgcagct agataaataa aagcatctcc tatatgaaca tatccattgt
    32461 ttccaccaac tggaatatgt aatatatatg ctattgtcag gcatattatg gatgcaaata
    32521 atgctgaagt aacaatatag gtagtttttt tagaagtaac tttattcatt ttttccaata
    32581 tactccctcc ctaaaaatcc agagctaaca taattgttat gttttcttat aaatatatta
    32641 atattaatca tacaattttc atagtttgtt aggtgttttt tttgtaaaat acagattgta
    32701 cccattcaaa tgtatataat tagaaaagta aaaataggta aaatgtatag agtaggagta
    32761 gttagaataa gttaatataa atttaatttg gtatgaataa gaagagtaca agtttaatat
    32821 aaaaaataat ataagagagt ctactcaata tatactgagc tgactctctt atatttggga
    32881 aattaaaggc tattttgtta gataatagct aattaatgaa aaaatatatt tataaaatac
    32941 taatttactc tattagtagc agttcctgtt tttataactt ctacagcact acttaaacta
    33001 gaataaacta tattttcaat cgctgtacta gtgaagaaac caaggtgatg agtgaatata
    33061 acttgttcca tagaaagaag tttatttatt tctgggtcag ttaattctcc aggattcatt
    33121 tttttgttta agaacaatcc ttcagtttca aatgtatcaa gggcagcagc tctaattttt
    33181 cctgactcta gtgcttctat taaatcccct gtattaatta aaccaccacg gccagtattt
    33241 actatgtaag ctccatcctt cattatagct agagtatctt tatttatcat atgttttgtt
    33301 ccttcaagta aaggagtatg taatgttata aggtcagctt cttttagaag gtcttctaaa
    33361 gaatctttgt aagttaatat atcatttaaa tcactatttg gatattggtc aaatgcaatt
    33421 acattagctc ctaggccttt gaataatttt gcagaagtag cacctatttt tcctgtacct
    33481 ataacaccaa ctgtaataga tctaacttct gttccaagaa gttcagctat ccaacggtaa
    33541 tcaccttcac agactttttt ctttactaga ggagtctttc ttaaaaggtt catagcttga
    33601 gtaacagcta attcagctat tgcattaggt gaataagaag gaacgtttgt aacgataagt
    33661 ccattttcat taactaaatc aaaatgtatc atgtcaaccc ctgcagttct tgaagctata
    33721 actttaaccc cagcatcttt taaagtttca taaatataag gattatctat atagttagtt
    33781 tgttgtatag atataccatc atacccttta gctttaacta cattttcttc agtcatgttt
    33841 tcaggataaa tatccacttg aacatcctta tgttcttcag accatttttt tattactggt
    33901 tcttcataat cgcgtgctcc aaatactagt attttcatat caataccctc ctgtaattat
    33961 taaattatta tggtaatttt tcatttagaa ataatatgta gcatataagg ttatattttt
    34021 tatacaaaat ttttaaggtt aaaaatttag ttttgaaatt gttttccctg tgttattttg
    34081 atatttagta attttttatt taatgtaata attactctaa aatttatcaa agaaattgtt
    34141 attttttaga ttaaatatta ttaaaaaatt atctaagttt gaaattagtt aactaacttg
    34201 ctgattaatt acaatgataa catgtgtttt tgagtttagc aatgaaaact ttttttgaaa
    34261 tgtcaagctt tttcataaaa aaatatataa aaaaaacttt tataagcata gaaagaatag
    34321 caaaatgcaa tggatagtgg caagatgcca cgatatgaaa aagattattc aattgcatat
    34381 tgttaaaaaa cattcaaatc aagcgatatt ttgattaaat ataaagttgg cacgataaat
    34441 gcttaacaat ataggtgtaa gacaataaaa caataaaaaa taattttaat aatttttaag
    34501 ttattttaga taagattagg aactttgaca tcagacagtt aatatcagaa aaaagtattt
    34561 tatgagtgat ttaatcgaaa ttttataatt gatactatta aggaggaaaa cgttatgctt
    34621 ttagaaggag ttaaagtagt agaactttca agtttcatcg cagcaccatg ttgtgcaaaa
    34681 atgttaggtg actggggtgc agaggttatt aagattgaac ctatagaagg tgatggaata
    34741 agagttatgg gtggaacatt taaatctcca gcatcagatg atgaaaaccc tatgtttgaa
    34801 ttagaaaatg gaaataaaaa gggtgtaagt attaatgtaa aatcaaaaga aggagtagaa
    34861 atattacata aattattatc agaagcagac atatttgtaa ctaatgttag agttcaagca
    34921 ttagaaaaaa tgggtatagc ttatgaccaa ataaaagata agtatccagg attaatattc
    34981 tctcaaatat taggatatgg tgaaaaagga cctttaaaag ataaaccagg atttgactat
    35041 actgcatact tcgcaagagg aggagttagc caatctgtta tggaaaaagg aacatctcca
    35101 gcaaatacag cagcaggatt tggtgaccac tatgcaggtc tagcactagc agcaggaagt
    35161 ttagcagcat tacataaaaa agctcaaact ggtaaaggtg agagagtaac agtaagtctt
    35221 ttccatacag ctatatatgg aatgggaaca atgataacaa cagcacaata cggaaatgaa
    35281 atgcctttat caagagaaaa tccaaacagc ccattaatga ctacatataa atgtaaagat
    35341 ggaagatgga ttcaattagc tttaatacaa tacaacaagt ggttaggcaa attctgtaag
    35401 gttataaata gagaatatat attagaagat gatagatata ataacataga ttcaatggtt
    35461 aatcatgttg aagatttagt taagatagtt ggagaagcta tgttagaaaa aacattagac
    35521 gagtggtcag ctttattaga agaagcagac ttaccatttg aaaaaattca aagctgtgaa
    35581 gatttattag atgacgaaca agcttgggca aatgacttct tatttaagaa aacatacgat
    35641 agcggaaata caggtgtctt agttaatact ccagttatgt ttagaaatga aggaattaaa
    35701 gaatatacac cagcaccaaa agtaggtcaa catactgtag aagtattaaa atctttaggc
    35761 tacgatgaag agaaaataaa taactttaaa gatagtaaag ttgtaagata ttaattagta
    35821 attctagatt ttttaaaagg agaatgctaa agatgtacac aatgggatta gatataggtt
    35881 caactgcatc aaagggagta atcttaaaga atggggaaga tattgtagct tctgaaacaa
    35941 tatcctctgg tactgggact actggaccat caagagtttt agaaaaatta tatggcaaga
    36001 caggtcttgc aagagaagat attaaaaaag ttgtagttac aggatatgga agaatgaact
    36061 attcagatgc tgataagcaa ataagtgaat taagctgtca tgctagaggg gtaaatttca
    36121 taattccaga gacaagaacc attattgaca taggtggtca agatgcaaag gtattaaaat
    36181 tagataataa tggaagacta ttaaactttc ttatgaatga caaatgtgct gcaggtacag
    36241 gaagattttt agatgtaatg gcaaaaataa tagaggttga tgtatctgaa ctcggaagta
    36301 tatctatgaa ttctcaaaat gaagtatcaa taagcagtac atgtacagta tttgcagagt
    36361 ctgaggttat atcacattta tctgaaaatg caaaaattga agatatagtg gcaggtattc
    36421 atacttcagt agcaaagaga gtttctagcc tagtaaaaag aataggagta caaagaaatg
    36481 tagttatggt tggtggagtt gctagaaata gtggtattgt aagagctatg gcaagagaaa
    36541 tcaacacaga aattattgta cctgatatac ctcaattaac tggtgcttta ggagcagcgt
    36601 tatatgcttt tgatgaagca aaagaatcac aaaaagaagt gaaaaatata taaaaagagg
    36661 gatgaaaatg tctgaaaaaa aagaagctag agtagtaatt aatgatttat tagctgaaca
    36721 atatgcaaat gcatttaaag ctaaagaaga aggaagacct gtaggttggt caacatcagt
    36781 atttcctcaa gagttagcag aagtatttga cttaaacgta ttatatccag aaaaccaagc
    36841 agctggagta gcagctaaaa aaggttcttt agaattatgt gaaatagctg aatctaaagg
    36901 atattctatt gacctatgtg catatgcaag aacaaatttt ggtcttttag aaaatggtgg
    36961 atgtgaagct ttggatatgc cagctccaga tttcctactt tgctgtaaca atatatgtaa
    37021 ccaagttata aaatggtatg aaaatatttc aagagaatta gatatacctt taataatgat
    37081 tgatacaact ttcaataatg aagacgaagt tactcaatca agaatagatt atattaaagc
    37141 tcaatttgaa gaagctataa aacaactaga aattatatca ggaaagaaat ttgaccctaa
    37201 gaagtttgaa gaagtaatga aaatatcagc tgaaaacgga agactatgga agtattctat
    37261 gagtttacca gcagattctt ctccttctcc aatgaatgga tttgacttat ttacttacat
    37321 ggctgtaata gtttgtgcta gaggtaaaaa agaaactaca gaagcattta agttacttat
    37381 agaagaatta gaggacaaca tgaaaactgg taaatcttct ttcagagggg aagaaaaata
    37441 cagaataatg atggaaggta taccttgttg gccatatata ggatacaaga tgaaaacatt
    37501 agctaaattt ggagttaaca tgacaggtag tgtttaccca catgcttggg cattacaata
    37561 tgaagttaat gatttagatg gaatggcagt agcatatagt actatgttta acaatgtaaa
    37621 cctagaccgt atgacaaaat atagagttga ttctttagta gagggtaaat gtgatggagc
    37681 attctatcat atgaacagaa gctgtaaact tatgagttta atacaatatg aaatgcaaag
    37741 aagagcagct gaagaaactg gattaccata tgctggattt gatggtgacc aagcagaccc
    37801 tagagctttc actaatgctc aatttgaaac aagaattcaa ggtttagttg aagtaatgga
    37861 agaaagaaaa aaacttaata gaggtgagat ataatggaag ctattttatc taaaatgaaa
    37921 gaagtagttg aaaatccaaa tgcggctgta aaaaaatata aaagtgaaac tggtaaaaaa
    37981 gctataggtt gtttcccagt ttattgccca gaagaaatta tacatgcagc tggaatgctt
    38041 ccagttggta tatggggagg gcaaacagaa ttagatttag ctaaacaata tttccctgca
    38101 tttgcatgtt caataatgca atcatgttta gaatatggat taaaaggtgc ttatgatgaa
    38161 ttatctggag ttattatacc aggtatgtgt gatacactaa tttgtttagg acaaaactgg
    38221 aaatcagcag tacctcatat aaaatatata tcattagtac acccacaaaa tagaaaactt
    38281 gaagctggtg taaaatactt aatcagtgag tacaaaggcg taaaaagaga acttgaagaa
    38341 atttgtggat atgaaataga agaagcaaaa attcatgaaa gtatagaagt ttacaatgaa
    38401 catagaaaaa ctatgagaga ctttgttgaa gtagcttata aacattctaa tactataaaa
    38461 ccatcaataa gaagcttagt aattaagagt gggttcttta tgagaaaaga agaacatact
    38521 gagctagtga aagatttaat agcaaaatta aatgctatgc cagaagaagt ctgttctgga
    38581 aagaaagttt tattaacagg tatattagct gattctaaag atatattaga cattttagaa
    38641 gacaacaata tatcagttgt agctgacgac ttagcacaag aaacaagaca attcagaaca
    38701 gatgtaccag caggtgatga tgcgttagaa agattagcaa gacaatggtc aaacatagaa
    38761 ggatgttcat tagcttatga ccctaagaaa aaacgtgggt cacttatagt agatgaagtt
    38821 aaaaagaaag atatagatgg tgttatcttc tgtatgatga aattctgtga cccagaagaa
    38881 tacgattatc ctttagttag aaaagatata gaagatagtg gaatacctac tttatatgtt
    38941 gaaatcgacc aacaaactca gaataatgaa caagccagaa ctcgtattca aacttttgct
    39001 gagatgatga gtttagcgta agttcattaa aataaattta ctataaaata tgaaaattgg
    39061 aggaagctat gttatataac aaagaacaag aacttttaag aaaagcagta agagattttg
    39121 ttagtaaaga attagatact ttaccagcag aaatggataa aacaggtgta atgcctaagg
    39181 aattaatcaa aaaattagct gatgcaaaat ttataagcag taatatccca gaagaatatg
    39241 gtggtggggg agcaggatat gtttcttacg ctatagtaat ggaagaaata gctagaagat
    39301 gtgcttcaac agctactttt gttacagctg gttcttctct tgcttcatta ccaatacttt
    39361 acaatggtac tgaagagcaa aaacaaaaat acttaaaagg tatagcaaca ggtgaattaa
    39421 taggagcatt tggtttaact gagccaggag ctggttctga tgcaggtgga caacaaacaa
    39481 cagcagaatt agttggagac cactatatat taaatggtag aaaaactttc ataactaatg
    39541 gaccattctg tgatgtagct atagtaatag cagttacaga tagaagtaaa ggacttagag
    39601 gaacatcagc gtttatagta gaaagtaaat gggatggttt ctcaacagga gctcatgaag
    39661 ataagatggg tataagagga actgaaactt ctgacttaat atttgaaaac gttaaagttc
    39721 caaaagaaaa cttacttgga aaagaaggtc aaggatttaa gatagcaatg ggtactctag
    39781 aagttggtag aataggtgtt gctgccttag ctctaggaat agctcaaggt gctttagatg
    39841 aagctgttaa atatacaaaa caaagagttc aatttggtaa gcctatagct aaattccaaa
    39901 atactcaatt tactatagct gacatggaaa caaaagtttg tgcagctaga ggattagttt
    39961 atgatgcagc acaaaagaga gatgcaggaa tgagagttgc tcaagaatct gctatggcta
    40021 aatactatgc atcagaaatt gcaaatgaag ttgcttataa agcattacaa cttcacggtg
    40081 gatatggatt tataaaagat tatgaaatcg aaagaatgta cagagatgct agaatcgtat
    40141 caatatacga aggaacatca gaagttcaaa aaatggtaat ttcatcaaac gtattaaaat
    40201 aataaataat ctaatgaaat tggaggtata gactttgaaa atattagttt gcgtaaaaca
    40261 agttccagat actaacgaag taagaataaa taaagaaaca ggtactctta taagagatgg
    40321 agttccaagt atattaaacc cagatgatgc aaatgcatta gaggaagctt taaaaattaa
    40381 agatgagcat gatgatgtaa ctataacagt tataacaatg ggacctcctc aagcagactt
    40441 tatgctaaga gagtgtttag ctatgggtgc tgatgatgca atattattaa gtgatagagc
    40501 atttggagga gctgatactt gggctacatc aaatactatt gcagcgggaa tatctaaagt
    40561 aggtgactat gacataatat ttgcaggaag acaagcaata gatggagata ctgcacaagt
    40621 tggaccacaa attgcagaga aattagacat tcctcaagtt acatatgtac aagatttcaa
    40681 aatagaagga aaagatataa tagttcaaag acaattagaa gatggatacg aattaataaa
    40741 agtaagtaca cctgtacttt taacagcagt aaaagagtta aatacaccta gatacatgtc
    40801 tgttgataaa atagtaaaag catataaaca tgatgtaaaa gtttggacaa ttgatgattt
    40861 agatgtaaat aaagaagaag ttggtttaaa agcatcacca actaaagtat ttagatcatt
    40921 tactcctgaa ccaagaggaa aaggagaaat cttagaaggt aaagctgatg aaatagctag
    40981 taaaataata atcggtctaa aacaaaagca cattatataa gttggaggag tacaaactat
    41041 gaatgatata aaagatttaa gttcttataa aaacgtatgg atatttgcag aacaaagaga
    41101 aggaaaaata gctccagtag ttatagaatt attaggagaa ggaagaaaat tagctaaaga
    41161 agtagatgca gaactttgtg caatattatt aggaaaagat gttgatggat tagctaaaga
    41221 attaatcact tttggagctg acaaagttta tgttgcagat gatgctcttt tagaaaaata
    41281 tacaactgat gcatatacaa aagtaataaa agatgcaata gatgaaataa aaccagaaat
    41341 aatgcttttc ggagcaactc atataggtag agacttagca cctagaatag cttcaagagt
    41401 tggaactgga ttaacagctg actgtactaa gttagaaata gacccagaag ataagaaaat
    41461 aaaacaaact cgtccagcat ttggtggaaa cataatggct acaatcattt gtccaaacca
    41521 tagacctcaa atgtctacag ttagacctgg tgttatggat aaagctgaaa aagacgaaac
    41581 aagaactggt gaagttatag cattagacta caaaataact caagatgata taagaactac
    41641 tgttttagaa acagttaaaa ctaagaaaga tttagtatct cttacagatg caaatgttat
    41701 agtatcaggt ggtctaggat taggtggacc agaaggattt gaaatgctta agaaattagc
    41761 tgacaaatta ggtggagtag ttggttcttc tcgtgcggct gttgatgctg gatggataga
    41821 ccattctcac caagtaggtc aaacaggaac tactgttaaa ccaaacctat atatagcttg
    41881 tggtatatca ggagcaatac aacatttagc aggtatgcaa tcatcagatt tcataattgc
    41941 tataaacaaa aacccagcag ctccaatttt agaaatcgct gactatggag tagttggaga
    42001 cttacatgaa atagttccaa tgcttataga aaaattagat agcgttgatg atttattaga
    42061 agctataaaa gcttaataga tacaaactat ataaatatta ctgattgaat aagtcttatt
    42121 agttagtaac ataattatta accctttgat aagttattgc tagtgtgtat ttgtcagtta
    42181 ttaaaaagtc tgtttgaata aaattttata atacaagata atctggataa tccttatatg
    42241 tatattgctt acaaattgtg agttatattc tgtaaggatt atctttgttt ttttaaataa
    42301 atcttaaatt taattaaatt gtattaaata gacaaataat tactaaatat gtgataaaat
    42361 acaattaaaa gcaaaatgaa atttttaaca aactataatc attaaaatta tatcttagtt
    42421 acgttttaat gaaataaact acttgaaaag acgaatatta taaggagttg attatatgtg
    42481 ctgatggtat ttattgtaag caaacaataa attttgtatg tagttcaata aattacttaa
    42541 tgaaaggtgc gaatattaat ggataataat ttaatagggc ttatagaaca tgtagaaaat
    42601 ccagccattt tatgtaaaga atcaggcgaa ataatatact gtaatcatct aatagatagt
    42661 atttttagtt ttctagatat aaaaaagcct agaaatataa atgaattaga ttcaaatttt
    42721 gacaaaacag aaatactgac agatagtaaa aagaaaatag ctttcagaga gttaaggatg
    42781 actgcacata tatacaatat gaaagataat aataatgaaa ataatatagt ttatttattt
    42841 gagaagtctc taatatctga taaagtaatt gaagatataa tagagcatat agatgaagtt
    42901 gttgttgtgt ttaacaaaga tggggtaatt gaaaagatga acactgtcag tgatgagata
    42961 ttacctttta aaagaactga ggtacttggt agaaatataa cagaccttgt gagacaagga
    43021 ttagttgaag aaccaataat attaaacatg cttaaagtga agaaaaagat ttatagaaat
    43081 atcgtttacc cagatgggaa gcttattgca tatacggcag ttccaagatg ggattctaag
    43141 ggaaagctta caggaggagt actaacaggg agagatattt caagggttat taagcttgaa
    43201 tctcagataa aatatagtga tatatcagaa gacacagagt atataagtca aagtaagatt
    43261 atggacaata taaaaaaagt tgttaagaga gctgcagcct cagattcttc tatatttata
    43321 aatggagaat caggtgtagg aaaagaaata atagcaagaa caatatataa gtatagttca
    43381 aggagagaca aaccttttat agctataaac tgtggagcta taccaaatga attattagag
    43441 tcagagtttt ttggatatga agaaggttct tttactggag ctaagaaaaa aggtaaaaag
    43501 ggactttttg aagaggcgaa tggtggaact attttcttgg atgagatagg tgagttacca
    43561 atgcagatgc aaaaaaaatt acttagggtt atacaagaaa atactattac tagaataggt
    43621 ggtagtaagc ctataaaaat agatgttaga tatataagtg ctactaatat ttctcatgaa
    43681 gaccttagaa ataaccttaa atttagacaa gatttgtact atagattaag tgttattcca
    43741 gtaaaaatac ctcctcttag agaaagaaaa gaggatatag taccattagt aaattatttc
    43801 ttaaaacttt acaatgaaaa gtacaataga gaagtagaag tttcgcctaa agttattgag
    43861 ttattagaag aatattcttg gccaggaaac ataagagaat taaaaaacat cattgaaaga
    43921 tttgtagtat tatcagctaa aaatgtaatt ggagaagatg aatttaacat gctgataaat
    43981 ttagatatga ttgataatga aacagatgat ttatcaccaa tagtggtaaa tggaattatg
    44041 aatcttaatg atgcatataa aatagtggac caaataatga taagtaaggc tataaataag
    44101 tatggttcaa taacaaaggc tgctgaagtt ataggtatat atccttctac catccataga
    44161 aagataaaga gtggacatat tcacgtttag ctgtcagttt aaaaagacaa tataattaaa
    44221 atattataag atacataatt tatacaactt aaaagagatg gcttaaaaat aaatttaatt
    44281 actttaagtc atctcttttc ttttataaat atttaaaagt tatattagtt tatagagtta
    44341 gcagaaccta aaacatcatc tatcttgctt tcaactacag cttgtatagc atctctacca
    44401 gcaccaatgt attttcttgg gtcaaattct tttggatttt cagctaagaa ttttctgata
    44461 gcagcagtca tagctagtct taagtcagta tccatgttta ttttacaaac agccatagaa
    44521 gatgcttttc ttaacatatc tacaggtaca cctttagcac cagctatatt tccaccaaat
    44581 tcattacatg tagcaacagc gttttggtca acagcagatg caccatgaag aactattggg
    44641 aaacctggta atttgctttg gatttcttct agtatatcga atcttaattt agcttctcct
    44701 ttgaatttga aagcaccatg agaagttcca atagctattg ctaatgaatc aacacctgtt
    44761 ctttcaacga actcaactgc ctcagctggt tgagtatact tgtgaacatc agaagtaaca
    44821 tcatcttctg ttccagctag aacaccaagt tctgcttcaa caacaacacc tttagagtgt
    44881 gcatattcaa cagcttcttt agttattcta acattttctt caaagtcaaa atgagaacca
    44941 tctatcataa ctgaagagaa accagcatca atacaagttt taatagcatc catatttgga
    45001 ccatggtcta agtgaagagc tacatctaca cctatttcat cagaagcagc cttaaccatt
    45061 tcaactaatg tatgaggtcc agcatattta acagctgaca tagaagcttg tatcataaca
    45121 taagaatttt tagctttagc agcttttaaa acaccttgta attgttctaa gtcacttatg
    45181 ttaaatgcac ctatagcaaa tccaccttcg taagcttttt taaacatttc ttttgtagta
    45241 attaatgcca ttttaaactc ctcctattaa cttttaaaat ttacccatca cttatattat
    45301 aacgttaaat caaaaaaagt atatagtaaa ttgtaataac tataaattac aagtataatg
    45361 ttaaatagaa gacaatagga ttaaataaaa taataaagaa tataaacaat ttaggaaaac
    45421 tagctatata atgctaacta taagggtagg aactacctta ttagtttgga gatactgata
    45481 acaatagttg ccttgaccaa gaagttacca cttcaaacgt tatcgaaagg aattaagtgg
    45541 atgataattc actaaaaatt taaaataaag gagataaact atgccacaga taaaaataag
    45601 aggaattaat gaaaatgata tatgtaaaat aagtgaaaaa atgataaatg atttagttga
    45661 agctgtaaaa tgtccaagag actactttga aatagaatgt ataaagtcag ttgcaataag
    45721 agatggtaaa atagcagatg tatatccttt tgttgaagta gcttggtttg atagaggaca
    45781 agaagtacaa gatatagtag caagaataat aactgatagt ataagaaata atttagatgt
    45841 agaaagtata gatttagcat ttacagtatt tgaaaaagaa aaatattatg agaatggaga
    45901 gcatttttaa tggctaaaaa gcaacgtata gataaaattc tttcaaattt aggttatgga
    45961 agtagaagtg aaataaagaa gtattgtaaa caagggtctg tagtagtaaa tggaagtgaa
    46021 gtttcaaatc caggaactca agtagacact gaaaatgatg agatattatt taatggagaa
    46081 gaagttatat atagagaata tatatatttg atgatgaata aacctgatgg atatatatca
    46141 gcaactacag ataaatatga cccaacagta ttagatttaa ttgatttatc atacttagct
    46201 tttgaaccat ttcctgttgg aaggttagat aaagacacag agggattatt agttttaact
    46261 aatgatggaa agctttctca tagagtttta tctcctaaga agcatgtgcc taagacttat
    46321 tatgcaaaaa ttgatggagt agttactgaa gaagatgtag aagctttttt agaaggtgta
    46381 gtgcttgatg acggatataa aactatgcca tcacagttaa atatattaaa aagtgatgat
    46441 gaatcagaaa tagagcttac aatacatgaa ggtaagtttc accaagtaaa aagaatgttt
    46501 gaaagcgtag gcaaaaaagt agtatactta aaaagattgt ctatgggcaa tttaaaattg
    46561 gatgaaagtt tagagttagg tgagtataga gagttaacag atgaagaagt aaaattgatt
    46621 gaagaaagat aataaagata ctatagtaaa ttggaggaat gtctgtgaag aaaaaagatg
    46681 ttatagaatt tgaagtagat aaaatggaat ttggtggtac atctttaagc caagttggag
    46741 atagagttat ccatatgaag ggtggaataa gtggtcaaaa ggtgagagct ggagttaaaa
    46801 aagttagaag taagaaagct gaagttaaga tgatagaatt attagagaac tcaccacttg
    46861 aaactgaaga aacttgcaag cactttagag agtgtggagg atgtacacta ttgtctgtgc
    46921 catatgaaaa acaattagaa ataaaagaaa aacaagttat ggatttattt ttaaagcaag
    46981 atttatttgg atttcagttt ttagggatag aaggaagtcc agaaaacaaa tattatagaa
    47041 ataagatgga atatactttt ggagatgaag taaaaaatgg acctttgaca ttaggtcttc
    47101 ataaaaaagg aaagcatata gatatacaaa ctgttgagga gtgtatgttg gttgatgaag
    47161 acttctcaaa gatattagtt tctagtgtag agtttttcaa tgaaaaaaag cttccttatt
    47221 atagaacaat gaatcacaaa ggatatttga gacatcttgt agttagaaaa gggattcata
    47281 ctaatgagat tatggttaat atagtaactt cttctcaaga agattttgat atgtatgagt
    47341 ttaaagatat gcttttaggg attgatttaa aagctgagtt agtaggtgta cttcatacta
    47401 ttaatgatgg tttagcagat gcagtccaat gtgatgagtt aagagtattg tatggaagag
    47461 attatataca agaagaaatt ttaggtctta agtttaagat ttcaccattt tcgtttttcc
    47521 aaaccaatac taagggagca gaggttcttt atagtattgc tagggatttt attggagatt
    47581 acaatgataa agttgtattt gacttgtata gtggtactgg gtctattgga caggttatgg
    47641 ctggtgctgc taagaaagtg tatggtattg agatagttga ggaagctgtt gttgctgcta
    47701 atgagaatgc taagttgaat ggacttacta attgtgagtt tattgctggg gatgtggcta
    47761 aggttgttaa ggatttaaag gacaagcctg atttgattat tgttgaccct cctagaccag
    47821 gcattcataa ggatgctatt agggatattt gtggatttgg tgctaaggag attgtttata
    47881 tttcttgtaa tcctaagtct ttggttgttg atttggttga ttttaagggg tatggttatg
    47941 agattaagat ggttaagtgt atggatatgt tcccaaatac gccacattgt gagactgtag
    48001 tgttgctacg tcgaaaataa tgctagaaat cttgagcttt agacagtttc atagacatat
    48061 aatatttaga ttagagggta ataaaattag gaataaagaa ttgaaaaggt gttttgatgt
    48121 gtctgtagtt atatatatgg agtgtgggaa tacgaaataa aaaaagtttt aattatagaa
    48181 atagatatta aatttataaa tttaatatct attttttatg tgaaaatata tttaatctaa
    48241 agaatgatat ttcataaaaa aaattaaata tatttttaaa atatttacaa tagagttatt
    48301 ttttattcgt ataataatag aaatatttta gcataagatg tataataaag gaaaaaatac
    48361 agaattaaaa aacataagat agataagtgg acttagggga gagaaattat tatgcaattg
    48421 acaaaaataa ttcttagtaa ctataggtgt tttggagaag aacctacaac tattgaaatt
    48481 aataatttaa ctggatttat aggtcataat agcagtggta aaactgcttt attaagtgca
    48541 cttatgaaac tttttggaga aaagtctagt gatagaatta ttgaaagatc agatttccat
    48601 atacctgaaa gtattgatcc agatagtatt tctaagaatg aattatatat tgaagcacaa
    48661 tttgagtttc ctgaattgga gagaggtaaa gacagcatat ctataccagt attttttaaa
    48721 aatatggttg ttagtgaacc aggtgggaaa ccttatttaa gaattagact tgaagcaaat
    48781 tgggagaaaa gctcaaatcc tgaaggaagt attgattcaa atgtatacta tataacatct
    48841 acaacagagg agataaatcc tgaagataag cgtaatatca aaagatatga gcttgatcaa
    48901 ataaagatga tttatgtacc tgccattagg agaccagatg aacagttaaa aaatgtctca
    48961 ggaacaataa tttcaagatt attaaatggt ataagttggt cagaacaaac aaaggcaaga
    49021 attaaaacga aagcaagtga aacggaggaa attttctttg aagaaaaagg ggttgaatca
    49081 ttaaagaaat cactcgaaac tcaatggaat agttatcata aggatattag atattctaat
    49141 ccaaagataa acttcaatag tactgattta gagacaattt taaaaaaagt tgaagtaact
    49201 ttttcaccta cagggacaca tcgagattat cgggttgaag agcttggaga tgggttacgt
    49261 tctttatttt atctttcact tgtaaataca tttttagaaa ttgaagaaga aattctaaaa
    49321 tctattaatg atggtaaaga agaagatata tttacattaa taccgcctgt attaacaatt
    49381 gttgcggttg aagaaccaga aaatcatatt tcacctcatc ttttaggaag ggtagttgaa
    49441 aaattaaatt ttatttctac aaaagaaaat tcacagacaa tattgacatc acattcacca
    49501 gcaatagtaa aaagaattga accaacagac ataaggtatt ttaggatttg taaggaatat
    49561 gaatgtacaa aagtgaagtc aattatatta ccaaatgaag aaaaggaagc agaacaattt
    49621 aaatttgtaa aggaatcagt attagcatat cctgaacttt attttgcaaa acttgttgta
    49681 ttgggcgaag gtgatagtga agagatcatt attaagcaga tgattgaatt aaaagcagaa
    49741 tctgtagatt catcagaaat ttcaatagta ccattaggtg gtaggcatgt taatcatttt
    49801 tggcgtttat taaatgattt agaaattcca tttattactt tgttagattt agatagagaa
    49861 cgagatggag gtggttgggg acgtataaag tatgcaatac aacaattaat aaatattggt
    49921 catgataaga atgtattact ttatacatgt gaaggaattt cacaagataa tgaatttaaa
    49981 gagatgcata cttgggatgt aactgatact gaaaatatgg ctaaatggat tgaaatgcta
    50041 aaaggttatg atgtttattt ttcagctccg ttagatatag attttgcaat gttacaaagt
    50101 tttaaagata aatatatttc agcattaaca agtgcggaag gtcctaggat aaaagatcat
    50161 ggaaaaatac aagatattgt gatcaatgaa gatgctgaag atgaatcatt gaaagctgct
    50221 tataaagata gaatagatag tgatattaaa tcaaccttaa aacaagaagg tggtgatgga
    50281 tctacttata ctgagggaga gaaagaacta atgatatggt attcatattt ctttttagga
    50341 agaggtaaac caactactca tttatcttta ttttctaata atactgatat agattttgaa
    50401 agttttccat actgtctaaa ggagtttgta aatagtatta ttgaaaagat gatagatgat
    50461 tcagggggtg gaagaaaatg aagaggaatt gggttagtaa agaagattgg agtccagcgg
    50521 ctggattcag actagaagtt gaagcgatga atacagttat taatgataag aatacacttg
    50581 ttgtagctgg tcctggcgct ggaaaaacag agttattagc tcagagagcc tgctttttac
    50641 tagagactaa tacctgtaga tatcctaaaa aaatccttgc tattagtttt aaaaaggatg
    50701 ctgctgaaaa tttaaaagag cgtttagaat tgagatgtgg gaaagaatta gcttcaagat
    50761 ttgaatcaaa gacctatgat gcttttgcaa aagaaatcgt agatagattt agaaatagtt
    50821 tagatgaagc atatagacct ttaaataatt acaatatagc tgaaaatcgt gatgttagaa
    50881 gagcatttga gatagcagga ttaaatttca gaggaaatca aactgaattt aataaagtat
    50941 atggaaataa actatcgata aataaattgc ctttacatac agattttgta gataagattt
    51001 ttatagatgc ttggaatgta ctacttaaag gcaacaaaga tactaatttt gtaagttcac
    51061 ttacttttgg tatgatatca cgtttagccg aatatttgat aagaaccaat aggtatatta
    51121 agaaagcaat tgaaatgact tatagtcatg tgtttttaga tgagtttcaa gatactaaat
    51181 ctattcaata tgatcttgtt aaagcttgtt tttttaaaac agaaacaata attactgctg
    51241 taggggatgg caaacaacga attatgttat gggctggtgc tagaaagtca atatttgaag
    51301 attttcaaaa tgatttttta agtcaaaaaa gaacattaat tatgaatcat cgttcagcgc
    51361 caagacttgt agagattcaa aaagcaatgt ataacagttt gaatgaagag gcaattgatt
    51421 taaaaactaa tgaaaagtgg aattatgaag atggagaagt gtatttaaga ctttttgagg
    51481 attatataaa agaagctgat atacttagtg aggaaatagt cgaattggtg gaaacaggta
    51541 tagaaattaa tgaaatatgt atattagtaa aacagagcgt agatatttat tcaaaagaga
    51601 ttataaataa actttctgaa cgtaatatta aggcgcgtaa tgaagcaatg tatcaggaga
    51661 tattaaaaga agatataata aagacactgg tttcgctttt taggttgtcg ttaagtgata
    51721 gaaatcccga tgattgggat tatatttacg atattctagg tgaattatat ggaatagacg
    51781 aagggtataa ccctaaaata ttaaatgatt tcattaccaa agtagaatta atgattaatg
    51841 atctcaaggt aaatttaaat attactgatg aaaaacaatt ttcagattta gttgattcta
    51901 aggttgaata tatttcatat gaaaaatttg catcaaagtt tcaaaaatat aaatctaaag
    51961 attattttga tgatttggta gataaattta aaaagctggt atggattgaa tataatgaaa
    52021 ctaaagattg gattaaagcg attgataact ttgaaggtaa aaattcaatt ccaataatga
    52081 caattcataa aagtaaagga cttgaatatg atactatctt ttttgttggg ttagaagatt
    52141 cagcattttg gaattttaaa aatcaaccag atgaagatag atgtgcattt tttgttgcat
    52201 tatcaagagc taaaagaaga attgatttta catttagctt agatagacca gcaggatttt
    52261 cgaattcaca gaagcattat tgtattaatg aattctacga attgtttgat aatactgaga
    52321 ttgtaaaaaa gatagagtat tgattaagat gataaaaact ttagtatatt atattttaag
    52381 atattagtta tataagtaga cattgaattt atgtatttga tgtctatttt ttatataaaa
    52441 atatattaaa gaaaggatga atttgcatga agaaaaaaac aaaaatatct aaaaagattg
    52501 taagttttat tatggttttt ataactatag ttactactat acttacatca tcagtttcag
    52561 cttatgctag cgagttggat atgagtgaac agacaggctt taattattta ggtattagtc
    52621 caattacagg aaaaaaatta atcataacat ttatcgtatg aagatggata ataaaattgt
    52681 attttgtgta gagccaggaa ttaaaacttc aagtggagga ggatatatat cggaggagtt
    52741 aggagataaa tttatatcta caacacttcc aaattatcat aaaagaaaag ctgaaatact
    52801 tgagaaggta aatagacata atatattacc ttcatggaat aatgaaaaag ttgcagttaa
    52861 aagtggagaa acaattgagt tagaagataa gaatggtatt attagagaaa tgcaattaga
    52921 atcaaataat actggaacag atatattact tgaagaaaat actttgaaaa ttacagcaaa
    52981 taaaaattct aattcaggag ttattagtta tataaagatt cctaaaaatg aggttggaat
    53041 atcaatagtt tatcgtaagc ataactatca aagcttatca gaatttcata tggaaagttc
    53101 gatgagtgca aatttaaata taaatgtaat caagttagga attgttaaag taaaaaagat
    53161 tgatgaaggc acaggaaagg aattagcaaa tgcaaaactt agatttgagt atgatggtga
    53221 tagtaaagaa attataacgg gttctaatga aattgctagt atagaagata ttattggttg
    53281 attaaaaagt gaagtatact tttgtatcta tgaaaaagac tataagcaat atataaaatt
    53341 agatatacct attgatgaag caaaaataaa aaatagattt gaaataaggt taaaaaatga
    53401 aagagcatat catgcagcag ttgatttgtt agcaaataga gatgaagaaa agacagcatt
    53461 ttcaattatt aatcgttata tacgttttgt tgataaagat gatgaaaaaa ttagaagtga
    53521 atggaaaact aatgatcagt ggagttattt tattggtgaa ggtagagcga agttaaaact
    53581 aacaacaaat ccagaaccat ataatattca aaaaacttta aattggttat caagacaagt
    53641 tgcaccaacg ttaaaaacaa ttaaaaggtt agatagtttg aacaactcaa cattaattga
    53701 gggcttaata aggtatgcaa gactaacaga taaacataaa aaaataattg aacaaaattc
    53761 agtaaatgtt gaagacatta tttatgatga ataaaaaaat gtaattagta ttgcagattt
    53821 taatataaaa gaagggagat atacgaatga attttggtca aaatttatat aattagtttt
    53881 tatcaaatgc acaatcattg gtattaatgg ctatagctat aattggtgta tatttaggat
    53941 tttagagaga gttttcaaaa cttataggat ttttagtagt tgcattaatt gcagtagggc
    54001 ttgtgtttaa tacagcagga gttaaagata tattattgga gctatttaat aaaataatag
    54061 gtgtgtaagg attaaaagag aatagaaaat tatgagtata tgatgaaggg ttctaataag
    54121 ttttattaaa atatatattg aaagacaagt agagctattt cgagttatta catgtaatgc
    54181 taatatatat aactgcattt tggaaattaa atacataatt agaaatagca aattttatag
    54241 gtgacttatt aatatgttta cttattgtat actatttgat atatttaata tgaggtgatt
    54301 cttgaaaatg gacatagtga aagtttttgc taacaatgtg agaaaatata gaaataaaaa
    54361 aggtctatca caagaagctt ttgctgaaaa agctggattg catagaactt atatttgtgc
    54421 tattgaaaga aaaaagagaa gtattgcttt agataatgtg cagaaaattg ctgatgcgct
    54481 tgagattgag acttacttac tatttataga aggtgaggag aaagaatgtc tatgaaaaaa
    54541 ttaccaatag aaaagcttat agaaaattta ggtttttcag ggtcaaagaa tcttgtgaat
    54601 atagatatgc ttacaaaatt agatatatct aaacatgatg taaaaacttt aaaagttata
    54661 aatccttatg caatttattt agtaaatagt aagccattta tattatttat agagtcttct
    54721 tttgaagaaa aaaaattaca acaaattagt aagcttatat ggaatgctca aataccaatt
    54781 gcttttatat gcgattctaa ttctgttaaa atatttaatg gaaaagcttt ggatttaaag
    54841 tcatatttaa ttgaggaaat atataatcaa tctattgagg atttttcgga agaatctgag
    54901 ttttcttatt tgaaaatatc tgatccatta ttttgggatc aatacactaa acaatatacc
    54961 aaaacgcatt taaatgatta tttgctagat aatattactt cattgacaaa taaattaaag
    55021 aaaaaatata aggtgaaatt tgcaacgaag cttgttctaa gattaatatt tattagatat
    55081 ttaatcgata gaggtgtcga tatagcttat aaaaatttta atcatgatat taaagcttca
    55141 caaaaagaac tgctaaagat tactaaaaac aaagttgaat tatatgaact gtttaaatac
    55201 ttaaaagaaa agtttaatgg taatttattt gagttaaatg acgaaattaa taatacttgt
    55261 ttaacagatg aagtgtttat tttactatct gattttttat caggtaaaat aagtattgac
    55321 aatggacaaa tgtctttatt ttcaatgtat gactttaata tcataccagt tgaactaatt
    55381 agtaatatat acgaaattct tttaggaaaa gaaattcgta ataaagataa cgcattctat
    55441 actccgaatt acttagcaga atatatttta gataaaacaa cacttgaatt tctgaaaaat
    55501 aataggcaat acaaaattct agatccttct tgtggatcag gagtattttt agtaaatagt
    55561 tttagacgta ttattgatat gaatttgggt gataaacttt tttgtgaaga tgataaactt
    55621 ttaaaagaac ttttattatc taatatttat ggaattgata tcaatgaaga tgctatcgat
    55681 gttactattt tctcgttata tctaactatt ttagattaca aagaccctaa gatattatca
    55741 gaatttaaac tgcctaattt aaaagggtgt aatttaatag cgagtgattt ttttgatgat
    55801 aataaattgg agagtttaaa gaaaattaac tttgatttta tcattggaaa tccgccttgg
    55861 ggaagtgtct cagatggatt acatttagat tattgcaata aaaatggcta taatgatatg
    55921 caacaaaaca aagaaatcag tagaagtttt atttttagag caaaagattt tagctctaga
    55981 aatacagtat gttcttttgt agtgcattct aaaatactat atactcaaaa aaagccatca
    56041 aaaaaattcc gtgaattttt gcttaaaaaa agtcaaatat ttagtgtagt tgaaatgtca
    56101 tctgtaagaa aattagtgtt taaaaatgca gacgctcctg cagcagttat atcatttaag
    56161 tataacgaaa gtgaagaaaa tttaaataat agaatcatct atacatcttt aaaaccaaat
    56221 gtatttttta aattatttaa cattattgta attgaaaaat atgatgttaa atatatttca
    56281 caaaaactat tattggagaa tgattgggct tggaaaacta ttgtgtatgg attcagtaaa
    56341 gatatagata taattatgaa tatcaaaaaa aaatatcaaa ctgtaaatga aattattttg
    56401 aaaaacagtt ttgttcatgg aacagggata caaatcaatg gtaatgaaag ccatgatgcg
    56461 acacatttaa aaggaaagtg gtatgttgat tcaaagaaag gaatagattc attctatgtt
    56521 gatataaata aagggaaaga acttactcaa gataaaatga gaagacctaa ggctaatcag
    56581 caagaaatat ttattcctcc atatgtatta ttaaaaaagg gagttgacac gaaaacatat
    56641 agatatagag cagcattttc aaatgatgca tttgtatatt cagatgcagt tacaggaata
    56701 tgtggaaaaa aagataattt aactacactt tattgcttga ctggtatgct taactcttct
    56761 ttttactcat acttaaatat aatgctaggt acatcaattg gaatagaaag agaacaagga
    56821 ttttcaacgg aaatttttac gtatccagca atagaaagtg atgaaattgc taatctggta
    56881 gtaaaaatac aagaagcgac taaattagaa aaaacaacta tgttcttgaa tgaaaaaaat
    56941 agttgtaagt atatcaaaca attagataag ttaattttga agtcttttaa tttaaatgat
    57001 gataaattta ttgactatgc aataaatatt caaattcctg agcttacaaa ttctaagtca
    57061 actaacatat atagaaaaat aactaaggaa gatttaatta attatagtga atgtttcaaa
    57121 gaacagtttt catcgatata tcgtagggtt gggaaaagta tttcaatttc ggtatatcca
    57181 aaaatattaa atcgttttac agtatttgaa ctagaagtaa cagatgaaaa aacagataga
    57241 gagattatgg ttaaagcaga agctgataat aatatggagt tgtttacgaa aataattaga
    57301 tatgattata atgatgtttt tcatcaaatt agagatatta ttcattttgg agaaaattca
    57361 ttttatatca taaagcctaa ttgctataaa tattggcatc ctgctatcgc agaaatggat
    57421 cttgctgatg ttttggatca gattttatct gatacagggg gtgaagaata atgggaggat
    57481 ttaaaaattc ttcactaaac ttttatttaa agcaagggct ttatgaaata attatagatg
    57541 gattaataga ctgttgttta cttatgagca aatcatgtat tgaacaatct agaaaaatat
    57601 taaatcacga agaaaagata agaacgcatt tagttgaaaa ttatttagaa aatgatattg
    57661 aaagaagaaa aacatcttta tctaaacaac atctaagatt tgaagtagaa gcacaagaaa
    57721 attatgacaa caaaaatgaa tcttatgagg gtagggttga tataaaagtt atatctaaag
    57781 acactttagc ggatagaagg gcttattata tcattgaatg taaaaggata gatggtaagg
    57841 aaactttaaa taaaaaatat ataaccgaag gtgtacaacg atttattact gagaaatatt
    57901 cttcgcatta tggcaaaaat ataatgcttg gatttatagt aaaagatata aatatccaga
    57961 gcaatataca aaaaattaat tcactgaatc agaacatatt atatacatat atagatacag
    58021 atatgttgac agttagaagt gattctgaaa ataattatgc tgtttgtgaa agtaaatata
    58081 aagtaaaatc taaactacta ttgttaaatc atatttttta taacttttcg agtataataa
    58141 gataatctta tgaatataaa atattactat gttaaaatta tagtttggtt ttgataatat
    58201 tataaaaata agtttaagaa taaaatataa aggaaaaaag gggcgtagca ctatttttta
    58261 gtgtgacagc ccctttaatt ttaaaatcgg taaggaggag tgtatttgaa aaaaattaag
    58321 tcatatacag ggattttgaa tgtggagaag gttatatatg caataaatga ttttcagctt
    58381 ccatttccag ttacttttac gcagatgaca tggtttgtat taacactttt tataattata
    58441 ttatttggta agttacctcc attatttatg atagaaggag catttttaaa gtatcttggc
    58501 ataccaattt ttataactta gtttatgtct caaaagactt ttgatggaaa gaaaccatat
    58561 ggatttttaa agtcaataat actatattca ttaagaccta aaataacata cgcaggaaaa
    58621 aacattaaat ttaaaaataa aattattgat gaaaatataa ctatagtaag gagtgaatta
    58681 tatgttcccg ataaaatata tagagaacaa tcttgtattt aataaggaag gagaatgttt
    58741 tgcatattat gaattaatac catataatta ttcattctta taagctgaac aaaaatttat
    58801 tgtacatgat aattttaggc aattaatatc acaaagtaga aatggtaaaa ttcatgcact
    58861 tcaaatagcc actgaaagtt ctataagagt tacacaagaa aggttaaaga aaaatattac
    58921 aggaaaatta aaagaaattg cttatgaaaa aatagacgag caaacagagg cacttgtttc
    58981 tatgattggc gataatcaaa ttgattatcg tttttttatt gggtttaagc ttttagttac
    59041 agagaaagaa atgaatataa agagtataaa aaagtcaata ttagctaatc tatcagattt
    59101 tatatatgat gttaataata aattgatgga tgactttgtc agtataaata atgatgaaat
    59161 tatgagattt ttaaaaatgg aaaagttatt agaaaataaa atctcaagaa gatttaaagt
    59221 tagaaggtta gataaaaatg attttggata tttaattgaa cataattatg gaaagaaagg
    59281 cacagttttt gaagattatc aataccattt acctacaaag aaacttaaaa gagaaacatt
    59341 agtaaagaaa tacaatctta taaagccaac tagatgtctt atagaagaga agcaaagata
    59401 cttaaaaatt atacatgagg attcagaaag ttttgtagct tattttacta ttgaaattat
    59461 tattggagaa atgaattttc catctagtga gatattctat tatcagcaac aacagtttgc
    59521 atttcctatt gatactagta tgaatgtgga aattgtaaca aataaaaagg ctttaactac
    59581 agttagaaat aagaaaaaag aattaaaaga tttagacaat catgcttggc agtcagggaa
    59641 tgaaacagta acaaatgtag tagaagcatt agaggctgta aatgagcttg taaataattt
    59701 aaatcaaaca aaagaatcaa tgtataagtt aagctatgta attagggtat cagcagatag
    59761 cattgatgaa ttaaaacgcc gttgtgatga agttaaagat ttttatgacg atttaaatat
    59821 aaaattagta cgcctaatgg gagatatgat aggatttcac aatgaattta taccttcaag
    59881 caaaaggtat ataaatgatt atattcaata tgtaactagt gattttctag caggattagg
    59941 gtttggagca actcaatagc ttggagagaa cgaaggaata tatattggat atagtttaga
    60001 tacaggaaga aatgtctatc ttcaaccatc tcttgcaagt caaggagtaa aagaatctgt
    60061 aactaatgcg ttggtagcag cattctttgg atttttagga ggtgggaaat catttgctaa
    60121 taacttactt gtttactatt cagtattgtt tggagggcaa gctgttttgg tggatccaaa
    60181 agctgaacgt ggcaaatgga aagaaaattt accagatata tatcatgaag taaatattgt
    60241 taatttaaca agtgatatag aaaataaggg aatgctagat ccttatgtaa ttatgaaaga
    60301 agtaaaagat agtggaagtc tagctattga tatattaact tttcttacag gaataagtag
    60361 tcatgatgga gagcagtttc ctatacttag aaaatcaatc ataaatgtta ctcaagacaa
    60421 atgcagagga cttttgaagg taatagatga attaaggaaa gataattctc aaatatcaaa
    60481 taatattgca gatcatattg aaagttttac agattatgat tttgcacaat tacttttctc
    60541 agatggaaat attaaaggct caattaatct agaaaaacaa atgaatataa tacaagttgc
    60601 agatcttgtt ttaccgaata aagatacttt atttgaagaa tatacaacaa tggaaagtct
    60661 ttcagtagct atgttgatag taattagtac ttttgcatta gattttatcc atacagatag
    60721 aagtactttt aaaatagtag atttagatga agcttggaca tttcttaatg tagcacaagg
    60781 aaaaacttta tctaataaat tagttagagc aggatgtgct atgaatgcag gagtgtattt
    60841 tgtaactcaa aatgcaggtg atgtatcaga tgaaaattta aaaaacaata ttggattaaa
    60901 atttgcattc agaagcacag atatcaatga aattaagaga atacttgaat tttttggagt
    60961 tgataaggaa gatgagaata atcaaaaaag gttaagagag ttagagaatg gacagtgttt
    61021 aatacaagat ttatatggac gagttggggt aatacaaata catctagttt ttcaagaact
    61081 ccttactgca tttgatacaa gaccacctat aagaaaagag gtggattaat gaaatcgaaa
    61141 gtatttagaa atttaagctg gataactatt ttaatagtag tacttttact attttttatt
    61201 tatataaatt tatagattta gagaaacaaa tagatacatt agataagaaa agaaaaaaac
    61261 tcatagatat gagattagaa gatataattg ataaagaatc atatgaagaa aagtatgatg
    61321 atttaacagt tgaaataaag aaacttagta aagagaaaaa aactcttaaa gcatcattaa
    61381 taaatgaaaa gagtataaaa gcaagactta gagaatttag aaagatactt gaaagaaatg
    61441 aattgttaga aaaatttgat agatatgtat ttgcaagtat agtagataag gttatagttg
    61501 gagttattaa tgaagatggt atagttgatc cttataaaat aacttttgtt tataaaacta
    61561 gctttgatga taaacaagat ggacataaat ttataaataa gagtccgtta gaaacgtatt
    61621 caaaagataa caacgataat aaaaagaagt gttcatatac taataatgag acattgcgag
    61681 actgtagtta aacttattag agaataacaa ggtttcagac ttttatattg tgtcttaaaa
    61741 gtagatttgc cacctatttg ccaccataat tatttttggg tggcaaattt attctacaat
    61801 gatttcaaaa atatttaccg tctggtttct catgttgtta gttacatgta aatatgtatc
    61861 catagttgtt gaagttttag catgtccgag tatatgctgg atatctttta tattagtacc
    61921 attttctaat aacatagtat cagggttttt aaaataaagt gtgtattctt ctaaagtagt
    61981 gataattaaa atatcaaata tcactataca aaggaaagtg cacgcttttt atgtttaaca
    62041 aaaacgaaat attaaaaaac ttattgaaga atatgatgtc aaaacaacta cagatattca
    62101 agatatgcta aaagatttat ttacaaatac aattcatcaa atatttacat tgtcgaattt
    62161 tagcggttta aacataatat attgactgat ataataaaat catagaatat tttaggggga
    62221 aatagattat gtttaagaaa aagttaatag ctgttgcaat gagtataact atgattagtg
    62281 tagggagctt ttcgtatgct cattcaggaa gaactgattc atcaggaggt catcgtgata
    62341 ataaaaataa atctggatta ggaagttatc actatcattg tggtggttat ccagctcatt
    62401 tacataataa tggtggttgt ccttatactg gaggaggaag cagttctgga acaacaactt
    62461 cggttaataa tgaagaaaag caaaagaggt ctgttggaga aaaaggatat aatcaagggt
    62521 atgaagatgg gtataaagga aattatagtt catcaaatta tagtggagat tatagtgata
    62581 catatgaatc aaagtactca gaaggatatg aaaaaggtaa ggctaaatta gaagaggaag
    62641 aaaaggtggc taaagagact ggatataatt tagggcttac aggtgctaaa tctaataata
    62701 catatgaaaa agaagtttta aaaaatgctt atgataccgg atattcaact ggatacaatg
    62761 aatataagac taaaaagata gaagaatata aagctaaagg gatagaggat agcaataaag
    62821 ataaggaaaa aatgacattt gaagaaaaca tagattctga atttatagat gcttataata
    62881 atgcttatga cgaaatacaa gaacaattaa aaaatgatta cactactcaa ggatttgaga
    62941 gtgctatcaa aggagaaaga tttgacacat caactatagg taatgttaaa tatgctaatt
    63001 ggtttaaaga aggatatgat aatggtaagg ttaagttacc taaagcaaaa gaaagtgtat
    63061 ataatcaagg ttacaatgaa gaagatttta gtataccaga tgaaatgaag tctattgaaa
    63121 ctaagttaaa aggtgtatat gatgaaggtt tagaaaaaag agaagaagag aaaagtagaa
    63181 atgctactta tggggttgga gctggaacag cagctgtagt tgctggagta gtatataaga
    63241 agaaaaaacg taaaaagata tagatgctag atataccaat gatgacaagt gtataacaaa
    63301 tataatttta agtataaata tttaaaatat agaagggaag gttatatcta tgggatttaa
    63361 ctttaggaaa agcataaatc taggaggagg actcaaatta aatttaggta agaagagtgt
    63421 aggtataagt gctggtgtta aaggtgctag agtgtcagtt aattcaaaag gaagaaaatc
    63481 agctacattg agtatacctg gaactggaat atcatataca aaaactagta caaagaaacg
    63541 taaacctaaa taaatatttg atatactaag aaatagactg ttacaaatag tctatttttt
    63601 agtatataga tttaaaaagt gacaaaattt tgaaatataa actaatttca taaaggaaaa
    63661 tattatttta tgtagaatta taatatttaa gtaatattat aaaatttata ggaggatttc
    63721 attatgaaat taagcaaaat actattggca atagggatgt ctgtttcatt attgattgct
    63781 agttgtccaa catcaaacgc tcttagttct attaattcaa taaaaggtac aaataagtat
    63841 gaaacagcag gtttaatagc agataaacaa aattatgata ttgcaatact tattaattct
    63901 gaaaatggat tatctgatgg attgtcagca agtggattgt caggagctaa aaatgcccca
    63961 atattgttaa ctaagaaaga tacaatccct tcagaaacat taaaaagatt agaaaaggta
    64021 aaagaagtat atctaattgg aggaaaaaat tcgataggag catcagttca gaaaatatta
    64081 agtgataaaa aaataagcat aaatagaata agtggaactg atagaataga tacaagtcat
    64141 aaagttgcaa aagaaatagg aagagtaagt acggttaaaa aagtaatatt aactaatgct
    64201 tttaaaggcg aaccagatgc tatgagtgtt gcttctatag cagttagaga taaatctcca
    64261 atagtattaa ctgatggaaa tactacaagt tttgctacag atggattaga aacttatgca
    64321 attggtggaa aagtcagtat gagtgataag ttaataaatg aaactaaagc aacaagaata
    64381 ggtggagtag atagatacga tacaaataaa caaataataa ataaatttta taatggctca
    64441 aaagaatttt acatagcaag tgggactgat ttagtttatt ctttagttgg ttctacaatt
    64501 gcacaaaaaa cacctatagt gttagttgga aatggaagta ataagagtat attaaaaaat
    64561 gcaagtaaaa taactgctat tggaaatatt gatgatgttg ttataaaaca atgtttaaat
    64621 ataactaata atgttgggga ttcaaataca ggtattgtaa aagatactaa ttcaaataat
    64681 acgaacaaac caagtaatga gcctagctct aataatcctg gattaactga taaaagtaca
    64741 gtatatgtaa ctcctaatgg aaaatcatat catctaacaa aaaattgttc tacactaaaa
    64801 agaagtaaaa caataaataa agtaacatta aaacaagcta agtcacaagg taaaatagat
    64861 ccttgtaatg tttgtgtaaa ataatgtatt agccaaatat atattaaaaa agacaattaa
    64921 ttaagattgt cttttttatt gaagaaatat aaatttatat tatgtattat taaaaaaaaa
    64981 ttattaatta taaaaaataa taataaagac gataagtatt aaaattttat gtttccaata
    65041 tttatgatat aattaatatg gcaaggaata aatatttgaa aaagctatga gtggtgtttc
    65101 catggaagtt tcttcacttt cttatgagag gaggtgaaaa ctatggaaaa tctaatgatg
    65161 agtattataa ctggtgttat agccagttac atttacgata aattaaagag ccactctgag
    65221 cgaccaacta agagtggctg ggaacttaat ataaagttcc agaaaagtaa atcttcaaaa
    65281 taatttgttg aaggaaacat cactcaaagt taagtaaaat atgtttcctt gcttttatta
    65341 tatcacaaat taaaaatatt aacacaaaat tttgtgaata tatacttatt attgttctaa
    65401 aaaaatatgt aaataattga tttgattgca tggaattatt gatgtaatat ttaagttaaa
    65461 tatacacaat ctcaattaaa gaagataagt actataaatt catatcaaaa aaatacataa
    65521 acttttaagt tataatttta taaaaagtct tttagtatca ttatttcaag aggaattatc
    65581 atatgaaaaa ataacttcat tagaaaagtg gataaaaaac tggtaa
//
LOCUS       DAEHWO010000012        61232 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEHWO010000012 DAEHWO010000000
VERSION     DAEHWO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.012"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(209..2179)
                     /gene="ftsH"
                     /locus_tag="KNP54_001007"
     CDS             complement(209..2179)
                     /gene="ftsH"
                     /locus_tag="KNP54_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBF0891926.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIIVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(2213..3601)
                     /gene="tilS"
                     /locus_tag="KNP54_001008"
     CDS             complement(2213..3601)
                     /gene="tilS"
                     /locus_tag="KNP54_001008"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBF0891927.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDGEGIICVGDYKISENYKIDES
                     TKEVLKINFNKL"
     gene            complement(3784..4212)
                     /locus_tag="KNP54_001009"
     CDS             complement(3784..4212)
                     /locus_tag="KNP54_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBF0891928.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(4229..5035)
                     /locus_tag="KNP54_001010"
     CDS             complement(4229..5035)
                     /locus_tag="KNP54_001010"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBF0891929.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(5237..5722)
                     /locus_tag="KNP54_001011"
     CDS             complement(5237..5722)
                     /locus_tag="KNP54_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBF0891930.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(5773..6432)
                     /gene="spoIIR"
                     /locus_tag="KNP54_001012"
     CDS             complement(5773..6432)
                     /gene="spoIIR"
                     /locus_tag="KNP54_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBF0891931.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(6577..7257)
                     /locus_tag="KNP54_001013"
     CDS             complement(6577..7257)
                     /locus_tag="KNP54_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0891932.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(7241..8131)
                     /locus_tag="KNP54_001014"
     CDS             complement(7241..8131)
                     /locus_tag="KNP54_001014"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBF0891933.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(8249..9799)
                     /locus_tag="KNP54_001015"
     CDS             complement(8249..9799)
                     /locus_tag="KNP54_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBF0891934.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVECIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(9893..10159)
                     /locus_tag="KNP54_001016"
     CDS             complement(9893..10159)
                     /locus_tag="KNP54_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBF0891935.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(10307..11167)
                     /gene="yabG"
                     /locus_tag="KNP54_001017"
     CDS             complement(10307..11167)
                     /gene="yabG"
                     /locus_tag="KNP54_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBF0891936.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(11251..12189)
                     /locus_tag="KNP54_001018"
     CDS             complement(11251..12189)
                     /locus_tag="KNP54_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBF0891937.1"
                     /translation="MKFLDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(12299..12460)
                     /locus_tag="KNP54_001019"
     CDS             complement(12299..12460)
                     /locus_tag="KNP54_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891938.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(12470..12967)
                     /locus_tag="KNP54_001020"
     CDS             complement(12470..12967)
                     /locus_tag="KNP54_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBF0891939.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(13082..13792)
                     /locus_tag="KNP54_001021"
     CDS             complement(13082..13792)
                     /locus_tag="KNP54_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBF0891940.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(13968..14498)
                     /locus_tag="KNP54_001022"
     CDS             complement(13968..14498)
                     /locus_tag="KNP54_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891941.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(14515..14745)
                     /locus_tag="KNP54_001023"
     CDS             complement(14515..14745)
                     /locus_tag="KNP54_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891942.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(14760..16154)
                     /locus_tag="KNP54_001024"
     CDS             complement(14760..16154)
                     /locus_tag="KNP54_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBF0891943.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(16280..17533)
                     /locus_tag="KNP54_001025"
     CDS             complement(16280..17533)
                     /locus_tag="KNP54_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0891944.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTIPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(17584..18738)
                     /locus_tag="KNP54_001026"
     CDS             complement(17584..18738)
                     /locus_tag="KNP54_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBF0891945.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGISGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(19298..19867)
                     /locus_tag="KNP54_001027"
     CDS             complement(19298..19867)
                     /locus_tag="KNP54_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBF0891946.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            20070..20297
                     /locus_tag="KNP54_001028"
     CDS             20070..20297
                     /locus_tag="KNP54_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBF0891947.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(20516..21259)
                     /locus_tag="KNP54_001029"
     CDS             complement(20516..21259)
                     /locus_tag="KNP54_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBF0891948.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            21427..22299
                     /locus_tag="KNP54_001030"
     CDS             21427..22299
                     /locus_tag="KNP54_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBF0891949.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            22299..22964
                     /locus_tag="KNP54_001031"
     CDS             22299..22964
                     /locus_tag="KNP54_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBF0891950.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            22985..23842
                     /locus_tag="KNP54_001032"
     CDS             22985..23842
                     /locus_tag="KNP54_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0891951.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(23998..26544)
                     /locus_tag="KNP54_001033"
     CDS             complement(23998..26544)
                     /locus_tag="KNP54_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0891952.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMINGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVISKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(26544..27230)
                     /locus_tag="KNP54_001034"
     CDS             complement(26544..27230)
                     /locus_tag="KNP54_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0891953.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(27313..28302)
                     /locus_tag="KNP54_001035"
     CDS             complement(27313..28302)
                     /locus_tag="KNP54_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0891954.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(28289..28975)
                     /locus_tag="KNP54_001036"
     CDS             complement(28289..28975)
                     /locus_tag="KNP54_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891955.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(29475..32681)
                     /gene="carB"
                     /locus_tag="KNP54_001037"
     CDS             complement(29475..32681)
                     /gene="carB"
                     /locus_tag="KNP54_001037"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBF0891956.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(32874..33923)
                     /gene="carA"
                     /locus_tag="KNP54_001038"
     CDS             complement(32874..33923)
                     /gene="carA"
                     /locus_tag="KNP54_001038"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBF0891957.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(34180..37386)
                     /gene="carB"
                     /locus_tag="KNP54_001039"
     CDS             complement(34180..37386)
                     /gene="carB"
                     /locus_tag="KNP54_001039"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBF0891958.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(37439..38482)
                     /gene="carA"
                     /locus_tag="KNP54_001040"
     CDS             complement(37439..38482)
                     /gene="carA"
                     /locus_tag="KNP54_001040"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBF0891959.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(38508..39224)
                     /gene="pyrF"
                     /locus_tag="KNP54_001041"
     CDS             complement(38508..39224)
                     /gene="pyrF"
                     /locus_tag="KNP54_001041"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBF0891960.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(39600..40235)
                     /locus_tag="KNP54_001042"
     CDS             complement(39600..40235)
                     /locus_tag="KNP54_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBF0891961.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(40259..41173)
                     /locus_tag="KNP54_001043"
     CDS             complement(40259..41173)
                     /locus_tag="KNP54_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891962.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            41774..43003
                     /locus_tag="KNP54_001044"
     CDS             41774..43003
                     /locus_tag="KNP54_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBF0891963.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(43208..45589)
                     /locus_tag="KNP54_001045"
     CDS             complement(43208..45589)
                     /locus_tag="KNP54_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBF0891964.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(45561..46286)
                     /locus_tag="KNP54_001046"
     CDS             complement(45561..46286)
                     /locus_tag="KNP54_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBF0891965.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(46276..46731)
                     /locus_tag="KNP54_001047"
     CDS             complement(46276..46731)
                     /locus_tag="KNP54_001047"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBF0891966.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(47013..48194)
                     /locus_tag="KNP54_001048"
     CDS             complement(47013..48194)
                     /locus_tag="KNP54_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBF0891967.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(48184..48876)
                     /locus_tag="KNP54_001049"
     CDS             complement(48184..48876)
                     /locus_tag="KNP54_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0891968.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(49010..49726)
                     /locus_tag="KNP54_001050"
     CDS             complement(49010..49726)
                     /locus_tag="KNP54_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBF0891969.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            49851..50585
                     /locus_tag="KNP54_001051"
     CDS             49851..50585
                     /locus_tag="KNP54_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBF0891970.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(50870..51721)
                     /locus_tag="KNP54_001052"
     CDS             complement(50870..51721)
                     /locus_tag="KNP54_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBF0891971.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDSIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(51747..52685)
                     /locus_tag="KNP54_001053"
     CDS             complement(51747..52685)
                     /locus_tag="KNP54_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBF0891972.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(52788..53438)
                     /locus_tag="KNP54_001054"
     CDS             complement(52788..53438)
                     /locus_tag="KNP54_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBF0891973.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(53587..53775)
                     /locus_tag="KNP54_001055"
     CDS             complement(53587..53775)
                     /locus_tag="KNP54_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBF0891974.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(53882..55066)
                     /locus_tag="KNP54_001056"
     CDS             complement(53882..55066)
                     /locus_tag="KNP54_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBF0891975.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTYLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(55208..56125)
                     /locus_tag="KNP54_001057"
     CDS             complement(55208..56125)
                     /locus_tag="KNP54_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBF0891976.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(56147..56875)
                     /locus_tag="KNP54_001058"
     CDS             complement(56147..56875)
                     /locus_tag="KNP54_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0891977.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(57071..57271)
                     /locus_tag="KNP54_001059"
     CDS             complement(57071..57271)
                     /locus_tag="KNP54_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891978.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(57396..57776)
                     /locus_tag="KNP54_001060"
     CDS             complement(57396..57776)
                     /locus_tag="KNP54_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBF0891979.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(58049..59407)
                     /locus_tag="KNP54_001061"
     CDS             complement(58049..59407)
                     /locus_tag="KNP54_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0891980.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            59855..60307
                     /locus_tag="KNP54_001062"
     CDS             59855..60307
                     /locus_tag="KNP54_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HBF0891981.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(60464..61081)
                     /locus_tag="KNP54_001063"
     CDS             complement(60464..61081)
                     /locus_tag="KNP54_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBF0891982.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
BASE COUNT        19386 a        11124 c         6689 g        24033 t
ORIGIN      
        1 ttattataat ggttgtttta tattttatat tgatgattta tataatttta cattttattt
       61 aaataatttt aaaataataa aaaaactgaa agtatcaatt aaattaatac atgcaaatat
      121 aatttgctta ttaatttaat attatacttt cagttttagt atttaatcca catcagataa
      181 taatcttaaa atgaccaagg tcttaaaact atttatcttt atcagattta tcttctaaat
      241 ttttatttat atcaataaca ttgtttcttt cttcttcatc tttttctaat tttatagtta
      301 attgttcttc aacttcttta gaagaatttt cctctgtaac tgcattttca atttcattca
      361 gaggtaactc tttattaaat gcttttacaa attgttctgc atctaaagtt tcatatataa
      421 gtaaagcttg tgctacatac tctaatctat ccatattttc ttgtaatata cttcttgtct
      481 tatcatatgc accatcaact atacgctttg tttcttggtc tatctcaaaa gcaacttctt
      541 cagaataatt tctcttactt gaaaaactat tacctaggaa tacttcatca tcactgtcaa
      601 atgacattgg accaagttta gaactcattc catactttgt taccatactt cttgcagtag
      661 ctgtaactct ttctaagtca tttgaagcac ctgtagatac atccttaagt actagctctt
      721 ctgctactct accaccaagt aaaactataa tattttcttt catttcattt tttgtagcat
      781 agaacttatc ttcaacagga agttgcattg taaaccctcc agctcttcct cttggaacta
      841 ttgtaacttg atgaacagga cttacttctt caagtacatg ggcacaaact gcatgccctc
      901 cttcatggta tgctgtaagt cttctttctt tctcacttat tactttcgat tttttagcca
      961 cacctgctat aacctttgtt atagcttctt ctatagtttc catcttaatt ttcttttctc
     1021 tttttctagc tgttaatatt gcagcctcat tcattaagtt ctctatatca gcaggagtaa
     1081 atcctggtgt tcttctagcc aagacatcca tttttacatc atcacttaat ggtttatttc
     1141 ttgagtgaac tttaaatata gcctctctac cttttacatc tggtgtacca acaacaactt
     1201 gtctgtcaaa tcttcctggt ctaagtaaag ctgggtcaag tatatctggt ctatttgtag
     1261 ctgccatgat tattatacct tgatttaccc caaatccatc catttcaact agaagttgat
     1321 taagagtttg ctctctttca tcatgacctc caccaagacc tgcacctctt tttctaccaa
     1381 ctgcatcaat ttcatctatg aatatgatag ctggagcact tttcttagcc tgttcaaata
     1441 aatctcttac tcttgaagca ccaaccccaa caaacatctc aacgaaatca gaaccactta
     1501 tactgaaaaa gggaactcct gcttctcctg caactgctct tgatagatat gttttaccag
     1561 ttccaggagg tcctaccata agcattcctt ttggtattct tgcacccaat tcaatatatt
     1621 tcttaggatt ctttaagaaa tctactacct cctgcaaatc ttctttttcc tcatctagtc
     1681 cagctacatc tttaaatgta actctagttt tttcatcatc tttatgaacc ttagcttttg
     1741 atttgccaaa actcataacc tttccgcctc caccttgaga ctgattcata aacacgaacc
     1801 aaataatcac catgaagaat attaacagta atgtaggcaa catttcgaca aaccaaggtg
     1861 tagatggctt agcttcacca ccaaaagtta gtttcccagc cttagcttgg tctaacacct
     1921 catctgcaag tttatttccc atcacttctg ttggaacata tgacttaaac tttgtatttg
     1981 tatcttttat agtaccttct acagaagttt gatttacaaa gtataatctt gatatattct
     2041 catctgttaa ttctctatat acttcagaga attttaaatc ttttattttt tctgtaggct
     2101 tacctgagaa ttgaactata cctactataa ttataaaaac aagtagataa aaacctgccc
     2161 cttttagcaa cttattcaat atagaagccc tcctttcata cattgctttg ccctataatt
     2221 tgttaaaatt aatttttaat acttcttttg tgctttcatc aattttataa ttttcactga
     2281 ttttataatc tccaacacat attattcctt caccatctgt gattatagga attttacatc
     2341 tttcttctct tgggattttt aaatctatga ataaatcttt cactttttta cttcccatag
     2401 caagctttat cttatcacct tgccttctgc ttcttattac tataccccct tttaccttat
     2461 taaaatcaaa ccctttagat gaattgtcta atttcatact cttataccta tctatgctca
     2521 ttacttgggt ctcaataatt tgttttaatt cttttatttt aataaaccca ttactaggta
     2581 cattgtaata aaattcaatt tcctcattaa caatttcctc attcgttaat attatactgt
     2641 ctttttttct ataaacaaat atatttcttg gaagagttaa cattttattt acttttgaat
     2701 tatcttctaa agacattata tcttctatat gtctttggtc aacaaaatta gtatctccta
     2761 gtatatgttt tatggaattt ctaagaactc taactttgat agcatcatgt aagcaaacaa
     2821 aatcgtctaa atttatctct acaaagcctt tttcttttat atttgaaact tctctaaatt
     2881 tagcttctgc ctctttctca atataatcgt tatcactttt taaactattg ctcatcctca
     2941 ctatagattc tattacattt gaattaaaat tatccttcat atatggtaaa aggtctaacc
     3001 ttatcttatt tctagtgtat atattttcta aatttgtttt atctatcctc ggatttaaat
     3061 tataagcttc acaatactcc tctatctcat ttctttccac gtctaatatg ggtctaatta
     3121 tgcaattatc tctaatataa tcaattccct ttaagccttt taaacctgtt cctctcatga
     3181 tacgcatcat aaccgtttcg gcttggtcat tgagattatg acctattgct attttattgg
     3241 ctttaatctt atccttaatt tcataaaaca tttcatatct tagcttcctt gctccttctt
     3301 ctaatgataa tccctcattt tcacaatatt ttggtacatt aatagacttt acaaagaata
     3361 taattcccat atcctcacaa agtttagata catataatgc atctttttga gcttctatcc
     3421 ctcttatttg atggtttaaa tgtgctgcat atatttctat attaaaatct ttttttaatc
     3481 tatttagtac atgcaataaa caaactgaat caggtcctcc agaaagacct aaaactattt
     3541 tatcgccttt ttgtattaaa ttatgtttat ttatagtact tagtacctta tcaaatatca
     3601 tatttatccc tcttacactt agttttattc acttttaagt atactttcta taaaaaaacg
     3661 ctaaaccctt gtatcaattt taagaaatta aagtttaata taaatataat aataccaaat
     3721 aaattaaata aaaggtagtt ttttcactac ctttataaaa tttctggaaa atagccatag
     3781 ttattattta gtacctatgt atatatctat tttattccta cctaaaaata aatcttgtac
     3841 ctttatatta tagtctattt tcaattttat gtgttcccct tcttgtatat ttatatctaa
     3901 ttctcttgta tcaatatcaa ttaataaagt accttgtggg gtcacatact ttgtagtact
     3961 actttctcca catttaaaca gcattgttga gttaatagca ccaaactttt tgatactaac
     4021 ttgattttta agtatcttta tagtattagt tatttctata tcttcttctt tttccttgta
     4081 aataacatat attccatcat ttttataaaa aattttacca aaggcagtca tctctatggt
     4141 gtccatattt cctttttcat catattgtct agtatttata cttattttta cactcaacga
     4201 tttttcctcc atagattctt catataaact agtatttttg tatttctact ttttgaatct
     4261 tatcaatttt tttctttaag aactctcttg ctatatctga aaatttttca ggtatatctg
     4321 atacataata ttgataagtt ccatgaattt ctgtattgtt tataatattt tgcacctcta
     4381 aaatcttttt taaatccttt gcagtctctt tagctggatt aacaagtttt atatgctctc
     4441 caacttcttc acctattgtt ctctttaaaa taggataatg agtacatcct aacactaaag
     4501 aatctatatt tttttctttc aattcttgta aatatatctt tgctgtcagt ttagccactt
     4561 ctgtatttgc ccatccttct tcaacaatag gcacaaataa aggacatgct ttattaacaa
     4621 tttctatact ctcatctatt ttagatattt ccaagttgta tgcttttgaa cttatagttc
     4681 cttcagttcc tattattcct acaattttgt tttttgtaga acttacagct gttctagctc
     4741 ctgcttctat aactccaatt atcggtatat catatttttc ttgagcttct tttaagcttc
     4801 ttgcagtagc agtgttacat gctataacta tagcttttac accttttgtt tttaaaaagt
     4861 ttatagcttg aaaagtatat ttaattatag tttctttgga tcttgaacca tatggtattc
     4921 tggcagtatc tccaaagtat attatatcct catttggtaa tatcttcatt atctctttta
     4981 gaactgttaa tccacctaat cccgaatcaa aaactcctat tggtttattg ttcatcttta
     5041 tacaacacct actttacatt tttgtgttta acaacaactt atttatcgct aaaatttata
     5101 tttatattca taattaatat attattacct aaatgattat tatagtttat tttacacaaa
     5161 aaataaagga gctatcttaa attagaaaat aatttctaca aaaagacaac tcctttcact
     5221 acttaaaaat ttaaatttat tttgcaaaca catgatttcc tattctcata taaggattca
     5281 atctatttat ccatttgcaa gtggctattt ctggattcca aaaatatact gctttattag
     5341 ttgggtcagt tccataaaga gcttcctgag ctgctttacg tgctgagtct gttggtgcca
     5401 tctttattga accatcaagc acaactgaga aagcattttt ttgatatatg acttcttcta
     5461 ttgtgtctgg aaatctaggg tccaatactc tatttattac tacagctgct acagcaacct
     5521 gtccctcata gctttctcct ctagcttctc ctgcaaccaa cttagataat aacatcaagt
     5581 cattatcaga taaatttatt acttctttct ttgctatatt tttttcttgt ttgtttactt
     5641 tcttaatatt ttctgttggt tcatatgcaa atacctcttt aataggcata aatataaaag
     5701 tcaaagctaa tagtgtagcc atcagtttac tccacctgtc catgattaaa accactcctt
     5761 acattcttat ttttaaaatt ttttctctaa atccttgact acttcaagta ctttaaactt
     5821 aatttttact ctacttgttt tttttggtgt atcttgtttt attaacttat attctttatc
     5881 agttaaaact tccttcaact tatcatctgt agatttatct atcactccat tagattcatc
     5941 aacaaaacat agtggaggga acataacaca ccaccagttt tttccttcac ctttcccaat
     6001 aataatcttt aatgctttat attcaccagc tggaagaact atattagaat attgtttagt
     6061 agggaaattg ctatattgta tacctacctt tacactgtaa ttatatccat ttttaagaat
     6121 aatattttta cttatttctt ccagactact atattccttt tttataatag cttcactttc
     6181 ttttatactt tttgaatttt gaagctttgg ctgtaaatat tttattactt catctctaac
     6241 ttttagttta agttcttggt cttcatctgt attgctgttt gctataacat gaaatcttat
     6301 taatttatct ttataatctt ttgatatatt gtctactttt tttacctcac catttattac
     6361 tattgtcatt attgatatga ctgatataag acttaatatt aatagtccca atctaatctt
     6421 aatttttctc attgaaaatt ccccctcaag ataaatttat atcatcaatt atgtccaatt
     6481 aaatttaatt tattcataat attttttaat actaataaaa aaagctatct taaaatgatt
     6541 acaatcattt taaaatagct ttttaaacct tatattttat aagtctttac taatcatagc
     6601 cttatctatc ataaactgct ctgctttttc tatatgctct gtagcatact tcttggatag
     6661 ctcactatca cctttaatta tagcatcaag taaatattta tgctcttcaa caatattatg
     6721 tgatgtatca taagcagaca tataggtaac tctaaatcta tatacttgtt cccacaatga
     6781 gtttattaat tggattaatt ttttattatt agttgcttta aatatacatt catgaaattc
     6841 tacatcaagt tttaataacg catctacatc ggattccaaa gtgctttttt taaattcttc
     6901 tgatatatct ttaagctttt taatatcttc atcactaatt ctttcagcgg caagatatgc
     6961 tgctaagcct tctaggcttg ctcttacttc taatacatcc ataatatcct ttaatgacat
     7021 atttgccaca tacgcacctt ttctaggcaa cataacgact aaaccttcta attcaagctt
     7081 tcttattgcc tctctcactg gagtcctact tactcctaat tgttctgcta gttgcacttc
     7141 cattagcctt tgaccaggct ttaattttcc ttctaagatt gcttctctta aattctcaaa
     7201 gactacatct cttaatggct tgtaattatc caagttcagt ttagttaaat tctccacaaa
     7261 tttcaacccc tttttgactg ctattaacaa catacacctg tttatatttt tttaataatt
     7321 ctttttttcc aattagagca tcttctttat ttttaaatag tccaaaaact gtaggaccac
     7381 ttccactcat catagaacct aaagcattat ttttcatcat tacttgtttt atatcactta
     7441 tttctttgtg tttacctata gtaacatttt caagaatatt taccatgctt tctgatacag
     7501 cttttatatc ttcagatttt aaacactcta tcaaatattt attatttggt ctttttttaa
     7561 tattattcaa atctaatcct tgataaactt ctttagtaga aacgaataag tctggtttgc
     7621 atatcaatat atttgtatca catggtaaac ctttgatatt tgttagcttt tctccaatac
     7681 cttgagctaa ggcaggtctt cctgatatac aaaaaggaac atctgcgccc aaattaagtc
     7741 ctatttcttt taattcatct tcagataatc taagttccca taggtgattt aaacctacta
     7801 atactgcggc tgcattagaa cttcctccag ccatccctgc tgctacagga atattttttt
     7861 ctatgaatat ttctacacct ttttttatat aaaatttatt tttaagtatt ttggcagctt
     7921 tataaacaat attatcttca tctaaaggaa tatctaaact agtgcttttt acctttattt
     7981 catcttcgtc taattctttt atctttacta tatcgtataa atctatcgtt tgcattatca
     8041 tttcaacaaa atgataaccg tcttgccttt ttcccaagac atcaatggat aaatttattt
     8101 ttgctctact ctttagtctt ataaaatcca ttctatcctc cttgtttaaa gaataatgca
     8161 tcactaacaa taatattata ctacaaaaaa taaaataata gggtattata ataccctatt
     8221 atacttaatt actttaaatt ttttaatatt aatctactaa tacgactttt ttttctaaaa
     8281 taagacactt cccaggctta attggttcat caagttttat atcattaagt tctgcaattt
     8341 cattttctgt tgtattgtat ttttttgcta tattccagaa agtatctcct tctttgcata
     8401 tatatacgat tatgctagga gctttagata aatcatatac accttggtct tctcccttga
     8461 taataaaatt ttctgctttc ttatctaatg cttcagtaaa tctcttaatt ttgataatca
     8521 agtctatctg gtccctattc aaatcaactt cgactttatc aatacatgct gtattaaaca
     8581 cagatgctgt atcagttaga ttatccattt ctatatcatg ttcaaatgga atttcctcac
     8641 taattttata aaccaatttt aaaccttcaa ctgggacaaa taaaatttca acttttatga
     8701 ttccttgtat aatgctttta tttccttcaa tataactatt ttctatagac atggttggac
     8761 aaacgcttac aatatctttt atttgtatat catcattatc atttcttatg ccttctctaa
     8821 ccataaatgt ttcttcacta cgtcttaaag tcttatttaa ttgaataggt ttgtggtcaa
     8881 attttattat cttttgaggc gaatatgcat cttgtaatac ttctcttgta acttcatctg
     8941 taacttttac cttacaacaa gccatacaat ctatttctaa aagacctgtg ttgctttcac
     9001 tattttgctt gaaaatatga ttaaaatctg acatagacaa caatacttct tcagtcatac
     9061 catcactaac tccagggact tctacaaatt gagtaaactc aatacctact ctatccaact
     9121 ctacaagttc accctcatat gtacaagcta acggatttat ttctaatact ccaccaataa
     9181 taactttatt gtcagtcact ctactttctt ttactttaac acatggattt aaacttatta
     9241 tagattgaat ttcctctgtg tttattgtta tagtatctct tatagaactt tctgcttttt
     9301 ctattccaac tatatcttga aaacaaattt cctttctgtg cttttgtatg cattccactt
     9361 gcgccacatc ttttacaatg tctaaccttt gcttttcaaa caaacttccc cttatattca
     9421 taagagctcc tactttaatc tttctctcat tcattatagt acaatccata tgctctactt
     9481 ctgaaaataa catgtattcc atatcttgaa taacattgtc tttttctatt acttcgttta
     9541 tatctacttt tccgtctaca ttagaaatag tatttttatc atctgcaata tagattacat
     9601 tataattaaa actacctctg caaagtatct tcccatctgc catttcaatt tttttaagtg
     9661 atatgtatcc ttctgttttt acaatttcat atacatctaa ttttttgtct ggcacaactg
     9721 cctccgcttc aatgaatgtt tgaaattttc caaagtctat tctattgtca actttaatta
     9781 catctttaat taattccata gtctacctcc ttaagtatta taaaaatatc acactatatt
     9841 tatatttaag gagcaaaaaa aaaattacac ctatttttaa ataggtataa ttttaactta
     9901 tttgtaattt atcttgatct ctaaaaactt gcaactttac attagatgtt aataaatctg
     9961 agtaactata agatactcta ggatatccat tactttcatc atctaacttt ataacaaaca
    10021 cgcttggata aactttttct agtataccct cttttgtaat aatctgcttt cttcctttat
    10081 tagctttcaa caatattttc tttcctatat gtctctctaa gcttactctt atcttatcta
    10141 gagtttgaac agtagccaca atatcacctt ctttaacgtt tatatgttta cataatatca
    10201 catataaaca tttttgtcaa atgtttaaac taattatttt atatattttt tgcaaaaatg
    10261 tcaatactat ttttgaagat atacagtata attatgttaa tttttgctaa tgtaatattg
    10321 tttttggcat tgcccatcta aattttcctc ttgtttcaga accaccaatt cccttaacac
    10381 ctgtaatagt ctgctctata acctcatcaa taggaactac tacatcaatt cttgaacaag
    10441 caattttctc cactataaaa acagggtcta atgcatgtat cattattctt ccaggcgaac
    10501 ttgcatagtt tgctcctgca cttattattt tttcataatt tgattggcat gctcctgcga
    10561 atatgacaag attatccaaa tttggttgcc atttacgtgc ttcttttact gttttaacaa
    10621 aatttgaaga gtttctatag ttactcatat cttctatatc tcctcttttt attgtcattg
    10681 catcatgacc tgttattact agtatatccg gattatattt ttctagtagt gctcttactt
    10741 ctttatactg attttgctct gaaacagcta cacctactgc aggtattcca agttgagcat
    10801 atacatccaa gcaaattttt aaatattctt tatctccatc tatctgtagt acttttccag
    10861 gcattccata tgtgttagga tttaattgaa gttttggaac tgctctagtc attctttttt
    10921 gtctttcttt agcttttctt actgacttat ataataaatt ttctacattt ttatctatta
    10981 atatatcttt tatatcaggt gcttttacta attctaggtc atcaatataa gcatctgcta
    11041 ttactctaaa tgcaattccc tttagtatag ctattttctc attattttca tctacaccaa
    11101 aagagactat tttaaatact atatctttgt tatgtgactt tctagctaca atgtctccta
    11161 ccttcatagt taaacctcca ataaattttt atcttagttt atactatgtt cgatataaaa
    11221 ctttgtttcc taatgtcaaa aaaacatttc ttataatact tcttttatca ctcttaaagc
    11281 atttttatag tatatctttt ctatatcatc ttcactaaac ccttcttttt ttagaggttc
    11341 atacagttta cccatctgag atatatcttc aatctcaact tttgaatcta ttccatcaaa
    11401 atctgaccct agagatacaa catctattcc tccaacattt acaatatgtt ttatgtgtct
    11461 aaccatatct tcaagtttac tttcactttt atcacttaaa aataagtgga agaagtttat
    11521 acctgtaact ccacctttat ttgctaatac tttaatcata tcatcagtta aatttctaga
    11581 atgattcatc attgctcttg aattagaatg tgtagcaatt attggtttag aagaaatctt
    11641 tgcaatttca taaaatccac catctgaaat atgagaaaca tcaaccaaca ttcccaattc
    11701 attcatctta tgtaccactt ctcttccaaa atcagtaagc cctttttctc tatattctac
    11761 tttattatga ggaaagctca attcattcac atgattccaa cttattgtca tcattctaac
    11821 ccctaagtcg taaaatttct ttaaattttc taatttacct tcaagtactg caccttcctc
    11881 aatagataaa agagctgtaa gtttaccttc tgattggttt ttcataattt cttcatagtt
    11941 agtagctaaa gctatttcat cactattttt tttcatttcc tcatgaaatt tatttgccat
    12001 actcatgcaa taatcaaaag gatgttttac ttcttcagta tcaacaaaaa gagcaaatgt
    12061 ttgagctaat gaatccccct ttttcaatct gtctatatca acagaatatt tattagactt
    12121 aagttcactt gtttctacat tttccattaa ttttgctata gtatcacaat gtaaatcaag
    12181 aaatttcata tttatacccc ctgtatattt tatatttata tctaaaaata gaaatagttg
    12241 tccttataga caactattga caactatttt ttaatattct ttttaatatt acttaatctt
    12301 attcttcttt taagttaggt attacttttt taacttcttc aatttgatgc catgttttat
    12361 ctatattatt ttcactaata tattttttta aatcagttaa agatgtaaaa tctttaactg
    12421 ataaattgtc atcatcatct gcaaatctta aaataaacat gagactccct tactttccac
    12481 aacatttctt atattttttt ccgcttccac atgggcatga atcatttctt cctatttttg
    12541 cttctttaac tattgtttta gacttcttat aagcctttat tatttctttt ctttggtctg
    12601 ctggtagtat atcttcccaa ccttgtaaat tatatagcca atgagcctca acagttacca
    12661 tattgttata taatttttcc caatctattt ttatagaaac ttctttatca gcttctactt
    12721 cttctaaaac tatatcttct tttaagcttt cacttattcc atctatgaat cccatgaaaa
    12781 attcattagt agttccaaat ttttcagcca attcacttac tttaccttca acaacatcca
    12841 ttttattatt taatatttca ttgtatattc cagcttcaac tttcaaatat tcttcccaga
    12901 attttacttc tgcttcttga ctttcatgat tatcacttaa atttctccat tcagtatata
    12961 aactcatact ttttcctcct aagtatacct atatttttat agtttttata gtataaaatc
    13021 ttttagttag attggaagtt tcttcttttt gattatacca tattctattt aaagttaact
    13081 cttatattat atcataatta aacaattctt ttaatacttt tatagcatac tcttggttta
    13141 taaaataagg gcttgtcgca attgttatta ctttggcttt tttaattaag ttttttatct
    13201 tgtaaaattt gagttcaaat ggtatatagt ccatatcact tgaaaatata tccaaatcta
    13261 tatcaagaac aaactctgat tctacttcta aatcaaatcc atatagacta tctattatta
    13321 ttaattctga aaatatgtta tattttaaag caggttttat aaaacttccc acatttaaaa
    13381 cttcatttgt atatctaaat acatctttta gattatttac atctacatca tagttctcag
    13441 gttctctagt atccttatgt tggtctacat gcactaactt gcatcctttt gtaaactcac
    13501 cctttaacaa agattttgcc caaaaataaa atgcatggtt atgattgtca aacacatata
    13561 tctttttatt tcccaggaca tattcgacca tattctccaa tccttttgct tttatttcct
    13621 tattttcatc tacttcatta aatactacct cattgcctaa ccttacatca tttaatgtac
    13681 catttattag ttttggaacg tatatgctct tattttctct tttatcatat gaaaatacat
    13741 tatttcctac tggtttttct atataaaatc cactatattc ataattttcc ataaaacttt
    13801 atttcctcca ttgttatata aatatataag ttataatttt aaaaattaaa atgcacttat
    13861 tgtaaatcat atcatctatt atagaaaaca tcttatataa ctaaatataa tatcttctct
    13921 caatatgtat tatacaataa gtgcaaaata tatttatata aaatatacta cattcctata
    13981 acaaaaccat cagcttcaat tggaaggtaa ctaactcttc tattcaactc cacctttcca
    14041 aaaaatacta cccaatatgg tctaaaaata ctttcaattt taactatttc aatctctggg
    14101 attcctccca taaacctatg agttaatctc atagccattt tatttgcctt tgcttttact
    14161 cttcgttcgt ccttatcact atactgcaca atattacaat ccacattttt tacaacttca
    14221 tatgtaggaa aatcttgtac tatactacca gaacctgtag aaccattcac taaaattttt
    14281 aattcattta tatcattaga atatctccta ttcttgaaaa tggatttcgt tttgtgaatt
    14341 ttaagtgtga taattttaaa ctctatataa tgaagtctaa cttcatgagc atatttgttc
    14401 tttaatatta gcttactaaa taaagaattt tttccacttt tagctatctc tatagcttct
    14461 tcttttgtaa ttcttatagg taacgctctt atatccataa aatcattctc tttcttattt
    14521 ttttcttgtc atttttaaaa ctctatatat ataatcaaaa aatattacaa ttacaactgc
    14581 cataactcca tatggaatta tttttccaac tataatatca tttctagtca atataccata
    14641 aaatataaat cctgttatta aaaagtacaa taatactaga aaaccgtcta ttccaagcca
    14701 ttttatttct aaatcttttt ttaccttaga cactaattta gacatagcag tttctccttt
    14761 tatagattat tttgtgtatt taaattttca ccgattctat taccaatcat ccatgcaata
    14821 aatgaaaaag gtatagctat cacaagaggc tctaactcaa agctctgaac tggaaatatt
    14881 ttaaaataac caaaagtcac tccaccaaca atcattccta aaataccacc catagatgtt
    14941 cttcttccat ttccaagaag cccacctact ataggtacaa atgccgaacc catccaaata
    15001 cttcctacaa atatacatgc atcatataca ttttcaaatc taaatgctac gctaagcccc
    15061 ataactgctg ctaaacatac acctattcta gtaaacttta ctaattgttt ctgagataac
    15121 tctttttttg taattcttcc atatatatca tttgctaatg tagccccagc tgctagataa
    15181 tagctatcca atgttgatat tatagaacct aaaattccta ttataaatat tactcttatt
    15241 ccttgtggta atgtatctaa aactaaagtt atatatccag cagctggagc catttctgga
    15301 taagtagctc ttactataag tcctgtcata gttaacacca tgtcaaaaca tatccatagt
    15361 gaaaaacagg ttaataaggc tcttcttcca accttaggag aatctgctgc tgaaaatctt
    15421 tgataaaaag ttgggtctga ataagctcca aaagaatata caattaacat caatgctttc
    15481 atagctgaca taccttttgt agggtgcata agctgtggtg catctttgag tgcttctgta
    15541 agaccttgaa accctcctat ttgttcaaat tgacctggca taaccatagt taaaccaaat
    15601 accatacaaa aaaacaatac catatctgta atggcaactc ccataagccc accaagtact
    15661 gtaagtacaa cgactactcc taccattatt aatcctatta attctttatc tattttccat
    15721 gctacgttac ctatagttcc catagcagtt atttctccaa gttgtgcaca atatataaac
    15781 atcaaaattg ccccaattat agcaacatgc ttgccataaa aactttccag taaatcagga
    15841 actgttatat tggttcttat atgaatcctt ggaccaaccc acaatgctaa aggcattctc
    15901 ccaatatgtg cagctattga ccaaactgcc catgcagata ttccatatat agccgcatac
    15961 tctacactac ctactgtacc aactcctcca taccatgatg caaccaaagt tcctactatt
    16021 aaggaccatg gtaaacttcg atttcctagg taataacttt ccatatcttt tacatttcta
    16081 gaaaaataat aacctattcc taataatata aatgcaaata taactataat cccattttcc
    16141 caaaatgtta acatatctaa tctccacatt cttatatttt aatttttaac tttaatatct
    16201 aaatatgaac aactctaccc atttccataa aaataggtag agttatataa taattataag
    16261 tatttaagta atcttgttat taagcaattt tattgtttaa acctttattt tctcttttat
    16321 ttattttatt taaagcataa gtagcaaata tccctataac tgcacatact acagataaaa
    16381 taaatatata tgtatatcct gtttgtccat atttatctaa ccaattacct gcaatagtgt
    16441 aataaaacgc atctggagaa aatcctataa atgaagcaaa tccaactact gctcctgtag
    16501 tttctaaaga tatattagac tctgaaacag atgcaaagta tatacctcta aatccaaata
    16561 aaattacact tagtattatc atgtttatta cagctatcca tataaatcct gtactcttag
    16621 gaataaccaa gtaagcagct gtacttactg tcattaatat aaatcctaca aacattactc
    16681 ttatagatga accaacttta tctgttataa caccagcaac tggagatgct cccattttta
    16741 taacataagt tcttattatt gataaagcag aaactagagt cattggcatt acataaactt
    16801 ctgataagta tggacttaaa taagttaaac ttgagaatac taaataagtt gaaaatatta
    16861 taagaccaat taaccaagcc tttggtattg taactacttt taacaatgac ttaatactta
    16921 atccttcatc tgatgctcca ctatcttttt tctcttccac taagaaaaat agaagtatac
    16981 cacatattat agatgctgca gaatataacc atactacata tttgaatcct actgttattt
    17041 cagcaaattt accaaagaaa taaagaccta taaaagaaat taatgtacct gatacacctg
    17101 ataacccttc ataaaaacca aatattcttc cttgctctga ctcacttcct tgcattctaa
    17161 caaccttaac agaggctgag aagaaggtta atattgtcgt aaatccccat aatacaaata
    17221 ttaaaagtat catactatat gatgggaatg tagagaaata aaatccaagt atccctgaag
    17281 caattaaaga aaaagttatt aattttctaa ctgagaatct atctgcaaac catcctccta
    17341 taaaataaga taccattcct actaatccat ataaactcaa taagttccct atttgtgtat
    17401 gacttaatgc taaagcttgt tgcattgggt cataaaatga tgatttcata tatggtaaac
    17461 tatacatagc tgttgttcca aatgccaata tgaatattat caaaaatctt ttaacattat
    17521 ttttgctttc cattgattct ctctccttaa aattttattg tttataatct cattcatata
    17581 attttatttt aatttttcta ttgcttgttt aaaatcattt attatatcat ttgaagattc
    17641 taatcctaca gctattctta ttagattttc cccattcatt tgaactaatg tatgctcttc
    17701 ccctaagctt gttgctattg ttgcaagctc taaagagttc attaatcttc tactagcttg
    17761 gtctcttgtc aatccactga taccatcctt aagtttaaat gaaactacgc ctccacctaa
    17821 accattcatt tgagttttac aaagctcata ttgaggatgt gattttaatg ctggatactt
    17881 taccaattcc acattctctt cttcctctaa aaactctgct actgctaatc cattttcaca
    17941 atgctttttc atcctcatat ctaacgtttt catacccctt aaaatcatcc atgcactcat
    18001 tggtggtaaa gatgctcctg taaaacaaca taaacttggc catctaacta aatctattaa
    18061 ttcttttgaa cctgctactg ctccccctaa agtatctcca tgtccattta taaacttagt
    18121 aagactatgt attactaaat ctgcacctaa atctattggt ctttgtacaa ttggtgtccc
    18181 aaaagtacta tcaactatag ctaagctttt attttcatga gcaatttctg ctattgtttt
    18241 tatatctact aagtctaatg atggatttaa aggactttct atataaacta ttttagtatt
    18301 tggtctcatt gcttctttta cattttgtgg atttactgca tctacaaatg taacttcaac
    18361 tccaaattta gataacaact cagacatgaa taatttagtg tgtgaaaata ttccatctga
    18421 actaactata tggtcaccac tttttaccaa tgctaatata gtagatgtta ttgcccccat
    18481 gcctgatgta ctagatatgg cactttctgc attttcaagc atagccaact tagcttctaa
    18541 ctctgtaaga gtaggattac actctcttgt atacacatat ccccatgtca tacacaactc
    18601 ttcaaaatgc tctactgtct ttgcagcaaa tgttgctgtt tgacatattg gtgtagccaa
    18661 tgcacctgtt gttgggtctg cactatgtcc ccaatgtatt atttttgtct ctaaatcttg
    18721 attaatattg ttactcattt tgatttcctc ccattttgac ttatttatac aacgttttcc
    18781 ctgccaaatt tcatcaattt agcttagtct taatacattt tttcaagtat acttttttat
    18841 ttgttataat ttctaaaaat atgacactta ttttgttttt ttacagttct aattataaac
    18901 tctatagtaa ctatagagtc aatatgtttt tgatattttt tttacaatgt ttaaaatagt
    18961 caatacaaaa ataggtatat cttagaataa ctaaagtcat cctaagatat acctattttt
    19021 atatcacaat ataaataatt acatataagc attagttttt ttatcataaa tagatttttc
    19081 aagatttatc attttttcat aaatatatta tagttaaata ttttaatatt acctaacatc
    19141 tacaataaaa tatactctta aaataaaatt atataattaa aaatactcta taaaagctaa
    19201 aaagtttttc tattcgctac atctaaaaat aattagatag aggtataaat gtatttagtt
    19261 tatttatacc tctagtcttt tataaattat atctctacta aattgatttt ttagcacgaa
    19321 taagtgtgct cttggagata ccagtcatct tcacaacctc tctatatggc ttagaattta
    19381 ataaccccaa tgcatattgt atctgttgat tgctgtattt ctttggccta ccatctttaa
    19441 agtccttttt ctttttagca aattcttttc ctaattgagt acgttctatt atcatatttc
    19501 tctcaagttc tgcaactgca agtaatgtag tcaaaaagaa tttacccatt gaagtatttt
    19561 ctaaaaggcc tatatttaaa atatgaacac ttacttcttt agcaaataaa ccttctatta
    19621 gttgtattcc ttctgatgta cttctagcta gtctatccag cttagttgca acaagtaagt
    19681 ctcccttttt tagagatgat ataatttttt caaatttagg cctgtttgta gtagtgcctg
    19741 tataagtttc ctttattatt ttagcatcat tatatttatt caaaatttct tgctgttgct
    19801 gatacaaact gttgttgtct gtttgatttt ttgtacttac acggcaatat ccatatataa
    19861 taatcatcac ttcctaacat aaagattttg tacagaagtt acccagaagc ttgtttttac
    19921 ttatctttat ccattttact aaaacgattt ttgggtgtca atactgttaa cttttgacac
    19981 cataataatt cctttataat ttgtttgact atgtcaaaaa ttaccaatat aatgaaatta
    20041 atgagtttat acaaattgga ggaaataata tgaatagtct gttaaaagaa gcaatagatg
    20101 aattaaaaaa catccattgc ggggaagttt ttttattaaa agaattgttc aaaggctatg
    20161 aatggaacag gttggagatg aatatcagat tgaaattagg aaaacttttt ttgtatgaag
    20221 tggtaactaa tcccaattta aatgtagagg tcatcaataa aaattctgct tatcagcaaa
    20281 tgtataaaaa aaaatagtga cttaaatgta tataatagta taatcttctt attgattcaa
    20341 aagttaaaac ttttaataca aaacaatcat tctattttaa catttatcaa tatgtctaaa
    20401 tttatataat taacacatac gaatagtatt gtttaaatca cattatttaa gatagataaa
    20461 tcttaaccct actccagcat aaatactaaa atagggctta gaattatcta tatttttatc
    20521 ccataaaatg cttagctctt cctcttgatt gaacatatat atctggggaa atacaataga
    20581 agcgtaaatt tataaaattt ccaaagtcag aaaacttcag ttcaaactta ggtataccaa
    20641 aactttcagg tgctatttcg tcaacgccaa aatagatgat aattccatta tctgtaagat
    20701 aaaatgcttg gtcttcaggt ataactaact caacattaga ataatacatt tctctatttt
    20761 catttatttg agatttaatg taatcagtaa ttatattaat ataatcaact ccatctctaa
    20821 aaatgtcatt aagtaaaagt tcttttccag ttgtcaaatc tatattgtaa ttattcaatg
    20881 tattgtattt aggcccatag ttattagcaa accccataag gtttaatatc atactcagta
    20941 cataattttt attaaaagta actgcgtaac tggtagatac ccaatagctt tgttttggaa
    21001 gtgaattttg agaagctgcg ttattatatt ctcgttcttc ttcctgtaag ccatttttaa
    21061 aattatttac agtcattctt acagcattgt ttatgttatt taaaataact gggtttacat
    21121 acgtggattg atttctaata ttgtatataa caggatactt tacatcatat gaaaaatact
    21181 tacttctttc aaaatcttca ttaaattgta catataatat attatatgta caggtatttg
    21241 tagattgata attttccatt aaaatcctcc cccttttata aaaaaatcag atacaatata
    21301 atatgcttaa aacagtaata atgttaatgg taaatgtaaa gaatagaaag tatctaaaac
    21361 agcaaaaaat gactaatttt gtggtataat acataggatt gagagttatt ttataggagg
    21421 aaaaatatgt tattattagc agataaatgg aaagattatg aacttataga tatgggaaat
    21481 ggagaaaaat tagaacgttg gggaagttat gtacttagaa gaccagaccc acaggttgta
    21541 tggccaatgg aatctgaatg ggctttatgg aaaaaccctc atggacatta tcacagaagc
    21601 aataaaggtg gaggtcaatg ggaacacaaa aaaagatatc cagaacaatg gactataaat
    21661 tataaaaact taaagtttca cattaaacca actggcttta aacatactgg attattccca
    21721 gagcaagcag ctaactggga ttggatgata gagaaaataa agaaagctaa cagacctata
    21781 aaagtgttga atctttttgc atatacaggt ggagctactg tagcatgtgc atctgctggt
    21841 gcagaagtat gtcatgttga tgctgcaaaa ggtatggtta attgggcaaa agaaaatata
    21901 gaattatcag gtcttaaaaa tcaaacagta agatttatag tggatgatgt tgtaaagttt
    21961 gttgaaagag aaataagaag aggtaaaaaa tatgatgcaa taataatgga ccctccttct
    22021 tatggaagag gtcctaaagg agaagtatgg caaatagaag aaaagttata cagttttgta
    22081 gatttatgta tgggagtttt atcagataac cctttatttt tcttaattaa ttcttataca
    22141 acaggatttt ctccaatagt tcttgaaaat gtattgtcta caacaatagg taaaaagaca
    22201 aatacaggag atatatacgg tggggaatta ggaataccag cttccagaga tggtaagata
    22261 cttccttgtg gtatatttgg aagatgggag aaaaaataat gataaaagtc atatatgaag
    22321 ataaccattt attagttgta gaaaaaccag ttaacatatt gtctcaagga gataatacta
    22381 atgataaaga tatggtaaat cttttaaaag actatattaa aaaaaagtat aacaaacctg
    22441 gaaatgtata tattggttta atacatagat tggatagacc agtaggtgga gttatggtgt
    22501 ttgcaaaaac atcaaaagca gcatctagat tgtctgagca ggtaagaagt aagactttca
    22561 aaaaaactta tctagctgtt gttcatggca agataaaatc taactcagat atactaaaag
    22621 attttttata taaaaataaa aaaactaata tggtaactgt agtgaaaaaa agccataaag
    22681 atgccaaaga agctgaactt aactataatg tattagattt taaagaaaat ctaagtttag
    22741 ttcaagttaa tttaaagact ggtcgttctc atcaaataag agttcaattt gcaagcagaa
    22801 aacatccatt atacggagac caaagatatg gcaaagaaat aaataagatt ggacaacaaa
    22861 tatctctttg gtccaataag atagaaattt gccatcctac tacaaaagaa aaaatggaat
    22921 ttacatgtca tccacctgac aaatatccat ggaatatatt ttaaatctca aatgaggtga
    22981 ttatatgagt aaaaaatttt caataggaga aatgtctaaa cttcataaaa taagcataca
    23041 gacactaagg tactatgacc aaatagattt atttaaacct gttcatgttg accaagaaag
    23101 caattacaga tattactcaa ttgaccaatt ttcacaatta gatattataa aatatttaaa
    23161 atatttaggt atgcctttaa aagaaattaa gtcaaagctt gatgaaaata atgaagaaat
    23221 tctaaaatta ctaacaaata aaattaatat agtggatgaa aaaattaaag aattagagct
    23281 tataaagaag gtactaagca caaagaaaga aactatggaa aaaggtatga aagtagatga
    23341 agttggtaaa atagtgagaa aacatattcc acgaagaagt atcttatcta tagagtatga
    23401 agaaggatta agtagtgaag aaactatgga actttccaga agacaaatag caaatatatt
    23461 agaagataat atatctgtgt tctatggtgg agtaagtgga cttgtatcta tagataaatt
    23521 tttaaaagaa gataaagtta tttatgacaa tagttttgtt actgttgaaa gagacttatt
    23581 tgatataaaa tcacaaaaac atataacaga aatttcatct ggtgatttta tttgtatgac
    23641 atataaaggg ccttacaaag aaaattatac cgcttttaag aaactggttg attatgttga
    23701 atataaaaga atacctattg aaaattatat atatgaaata cctataatag accctctgtc
    23761 tacaaacaac gaagaggaac ttctaacaga aattcaaata caagttaaaa agagagaaat
    23821 tgacttaaga tgtctagtgt agtaatctag tttacttaca catcttaata tagttgtcta
    23881 ttatcaacat atgatttttc tagatagtga ttcctaacag tgagattttc aaaaaatagg
    23941 aggaaatatg gctaatgcta attccctcct atttttaatt aagccatatc attttaatta
    24001 agccatgtca tcacgaagtg catcaataat attttctttt tttatcttat taatagtata
    24061 caacattgta ataaatacta taaataaaac actaaatata ctaattccaa tactaaacca
    24121 tggaatcaca aaatcaatat catctgtaac cattacttta tgaattagcc atgaagaaat
    24181 tactgctata ggaagtccaa agaacaatgc tctcatgcca taaaaggcac actcaaaatt
    24241 catcatcttt tggaaatcat gctcagacat tcctacagag cgaagcatgg caagttctct
    24301 acgacgtaac ttaatattag ttgaaattgt attaaacaca ttggcaatcg aaatcagaga
    24361 aatcataatt atgaaagtat aagcaaaaac attggcaata aaaatgtaat tacggttctc
    24421 atccatcatt ccatacatat tgtacagatt gtactcattc gtaactccct cactctcaat
    24481 aatttgctcc atttctgcaa ctgactgagt aggatttttc gattgaaagc ttaaactttc
    24541 aattcctgta gaaacaccag gaatctcaaa cttatctttg gctgaataag gagccaatac
    24601 tctgaagctt gctttcttca catctgaact tctgattcct ggaggagaat caggtggcac
    24661 tactttgaca aatgaaatat tcacattttg tctctcaggt atctccaact tgccattagt
    24721 ttcaggagtg aggctaacat tcatagaaga actgttgaaa atatcaataa tattattatc
    24781 ctttgttacc atagaaacag caatcagttt tgcattttgt ccagtatatt cttctgctgg
    24841 taatccaaga cttttaataa tattcagata agttctatca tcaagaaatt gcatatctac
    24901 tggtaattca agcatttcac tcatagaatg tgaaccctca tagttcaaat aatcgtctgt
    24961 aagctcactt actttggcaa cacatgaata ggtcataagt ttctgataca aaccttcgta
    25021 aacaccattt gcagttttta gcttatcgta aagcttcaac atttcgttgt ctttcatacc
    25081 ttgtgtagaa aaaataatat cctggtcagt aacctctgac ctctgatttg acatctgttt
    25141 taggtctgct actaaagcac ttgtagatat aaatagaact atgcttaaaa caagcgacaa
    25201 tacaatactt cgataacgtt tcttgtttct tttaaagttt ttcatagcaa gaactccctc
    25261 aagaccataa actcgctgtg ttagttttga tgtcttcaca gatttagatt caatttttac
    25321 ctcatttgtc tgacgaatac actccatcac tggtgtgttg gcagcctttc ttgctggtat
    25381 gtaagcagaa attaagattg taaccatact taccactgct gcaacgatga ttgcagggat
    25441 agacaatgtt aatgtcaacg gaacgtttac atagagaata tttgcaaagt ttttagatat
    25501 gacagaaatc acaagtccaa tactgactat accgattgca acaccaattg gtataccaat
    25561 cgcaccaatg caaattcctt caaatagcac cgaatttcgt aactgttttg ctgtagctcc
    25621 aacagatgaa agtattccaa attgatgtgt tcgctcgttc aatgacatgt taaatgaatt
    25681 atatattaga aaaattgagc ctagcatgat tatggcaagc acaatgccac caaccgagta
    25741 caaaaacata ttgaacaaat tgttatcaga gacacctatg aatcgcaaca cattgtcatt
    25801 gaaaatggaa gcatggtctt tagtgctact tgtgtaagag cgaatctgat gtggattttt
    25861 caatgtgaca aaaaggctaa gactgtcagt cttgacttgt ttatcttctt tggttatcaa
    25921 ggtatatcct ggtgcagaag attcttcaaa tacgggcttt ctacagatac ccacaactgt
    25981 ataagttttc ttatcctgtg gcacaaaaac ttcactccca gcagtgtatg ggtcactctg
    26041 accaagcttt tcattttcac tcattcgttt ccctacatcc aaagaaatag tatcccctac
    26101 tgcaaatttg acaccaccat ctgtcgcaac tttacttgaa acaagaatct ctctactatt
    26161 ttcaggtaat cttccagaaa ttaaagttat aggcaaagta tcaaaagctt ctttgctaaa
    26221 tccagcaata aaaagatatg gtttatctgg atttctgtta ccttcaagtg ttgcatagcc
    26281 aatattttca aatgttgcag tatttgcaac ttcatcattg actctttgtt cctgtacaaa
    26341 agaagaatcc acatccaaaa actggacatg ccaatcacca tattttataa tagctccatt
    26401 tatcatatag ttcatcaaag aaactccaaa ggtagtaact gctgtaatca tagcagctga
    26461 cagaacaact cctataattg ttacaagagt tcgagttcga ttctttttca atccttgcag
    26521 agcaactttg ttaaaaatgt tcattaacga ttcaccttcc tctcatcacg cactactttt
    26581 ccatctgaaa tacagataat tctatctgcc tgtaaagcaa tgttttcatc atgtgtgaca
    26641 ataatgagag tttggtgata tttactatgg ctctctttca gtaactggat aatctcttgt
    26701 ccatttttac tgtctaagct acctgtaggc tcatcagcaa gcataactgc tggtgcattc
    26761 atcaatgcac gaccaatggc aacacgttgc tgttggccac cagaaagttg atttggtaaa
    26821 tgtgtttttc gttcttttaa accaagtaat tctaacaagt catttaaccg ttcttgattg
    26881 accttacgct tatccataag tataggcaat gtgatatttt ccactacatt taatgtgggt
    26941 atcagattgt gaaactgata aatcaatcca acttgtcgcc tacgaaaaat agcaagtttt
    27001 tcattgcttt ggccatatac atcttgcccc tccagatata tctttccact tgttggtacg
    27061 tctactcctg caatggaatg tagtagtgta gatttaccag aaccagaaga accaatgatt
    27121 gcagtaaact cccctttttc aatagtaagt gagacatggt caagtgcagt aaccttattt
    27181 tcattcttac cataaacctt acataaatct tcaatcttta aaaacgccat tatataagtc
    27241 tcctttcata ttttataaat atatcataga actttcaact tacatttaag tgacatttaa
    27301 atgagagatt cgtcactttg gaaaacgaat aacaaatatt gcaccacctt gtgggtgatt
    27361 ttgtgcagta attgttcctc cttgtctcat aataatcgtc ttacaaagtg ccaatcctat
    27421 tccataaccg gctgtgcttg aatttttccc acgataaaat ctgttaaata gacatggtaa
    27481 atcttctttt ttaaagcctg ctccgttgtc atgaatagta agttgagtaa acaaaaagtt
    27541 gtcctcacaa atgatatcaa tttttccatt atcacccaca ctctccatgc agtttttaaa
    27601 tatattttga attgcttctg aaagccaatt taaatcaccc aaaatcctta ctccttttgg
    27661 tatatcaata tgtaaagtga tattgtgcag ttccatggga atcaaaagtt gatgaagtgc
    27721 agaactaatc aaattattca catcaatttg ttctttttga aagactacaa tacctgcatc
    27781 taaacgtgat aattttaaaa gggaagtaat cagccagtcc attcgtataa gtaattcctc
    27841 tgtttctcgt atcaactctt ttctctcatc ttcatcagaa gtattctcta acagtgacaa
    27901 aataagagtt actgatgtaa gaggagtgcg aagctggtgg gctatgtcag ctagtgagtc
    27961 agcaaggtgt tctttttctt ttttcagtgc gtaattttgc tctctaatgc gtaacgtcat
    28021 tttagttatt tcactttgta gaatagaaag ctcaccctca tctgattcag caatatacag
    28081 atggttagca ttatgaagca caagattaat ttgttctgaa atctgtgcaa tacttttgta
    28141 tcgattttta gtaaacacaa aaaatgctat tccaaaggta gtggcagaaa caatagaaag
    28201 tattccagtc ataatactga ttgcaaatcc cagggctaca gtgagaatag taattaataa
    28261 gaataaaata gcaaattttc gaaactctct atttcgaaac ataacttccc cccaatctat
    28321 accctgtccc acgaacagtc aaaattattt gtggacttga agggtcatct tctatcttct
    28381 ctcgcaagcg tttgatgtac acagtcaatg tgttgtcatt aacaaactca cctgccgcat
    28441 cccacaattc atcaagtaat cttaccctcg taataatact tttaggattg ctaataaaca
    28501 ccaataacaa acggtattct aaagctgaaa gaaaaacctc attgccattc tttttcacaa
    28561 caccagttgc tgtatctaca taaagcccac aaatttcaaa agttgaccca aaacgcccac
    28621 tttttcgtag tgctgttcta attcgcgcaa tcagttcacg tggacgaaaa ggtttagtaa
    28681 tataatcatc tgcacccata ttcagtccag taacaacact tgattcatca ccggaagctg
    28741 tcaaaaagat aacaggaatg tcttgctttt ctttgatttc tgtgcaaatc gtaaacccat
    28801 ttccatcagg taaagaaata tcaataagtg ccaaatcaaa tttattctta gcaatctcta
    28861 caagtgcttc acttcttgtg gatacatggg ttactataaa tccttctgaa ttaagcaaaa
    28921 gaataagatt tttggcaatt gctttatcat cctcaactaa aaatatccgt ttcatttact
    28981 ttcatcctcc tttattttat tagttttata tattccagca gagcaatagt acactactat
    29041 tttacttatc attacacaat tttcagtagt ttcttttgtt cttatataat ccatgcataa
    29101 tacctccatt gatttattat atttcttata acataaatac acaagataag acaaaaaaca
    29161 taatgtaagt gcaagttttt taactcacta acttataaac atacactcct actaacacta
    29221 ctttcttgat gacacatctt acaagcttat attcatacat caatgaaaaa ttaaatttat
    29281 ccatttatta aaataaaagg caatagcttc tatagctaat gccctttatc ttaaaatgat
    29341 ttaaatacta tacaattttt ataaatggct ataaataaac tcgtatagaa tataaaattt
    29401 atctacagtc ttttgttata caaaatttat aacctcttat agaacaaatt taccactttg
    29461 caaacttatc acttttactc agctatatta taaactttta atttatcttt gtttaaatgt
    29521 ttcttcttaa cttctactaa agcttttagc gtatccaaag atgtcattat ttcagtagaa
    29581 aattcaatgg ctgttcttct catcttaaat ccatctcttg tagagtcatt tcctttagtt
    29641 ggtgtattta ttactatatc aacttgttta tttcttatag catctaatat gtttggtcta
    29701 ggttcttcaa ttctatttac tatatcagcc tctattccat tttctcttaa actcttcgct
    29761 gttccttctg tagcaacaaa agtatatcct aattctttca tatcttttgc tatctctata
    29821 aactcatctt tatcatgatt atttacagta gcaagtacta ctcctctttc atcagacata
    29881 tgtctacctg ctgccaagaa ccctttatat aaggcttctt ctaaattttc tcctacacct
    29941 aggacttctc ctgtagactt catttcaggt cctagactta cttcaacttt agataattta
    30001 gacattgaga atactggtac ttttactgat actaattttg gctctttgta aactcctgta
    30061 ccatatccta aatcctttaa tttagctcct aacatacact tagtagccaa gtcaactatt
    30121 ggtactccac ttactttact tatatatgga actgttctac tagctctagg gttaacctca
    30181 attatatata attcattttg aaattctata aactgtatat taaccatacc aagcacatta
    30241 aggtctaaag ctattttttt agtgtattct actatctttt cttttatttc atcagatata
    30301 ttttgacttg gatacattgt tgtactatct ccagagtgaa ctccagctct ttctaaatgc
    30361 tccattatac caggtatcaa tatatcttct ttatcacata tagcatctac ttctatttct
    30421 ctaccagtta gatatttatc tataagtact ggatttttat ggtctctatc aaatgcatca
    30481 tccaaatact gaattagttt ttcttcgtta taagttattt ccataccttg accaccaagt
    30541 acataagatg gtctaactaa tactggataa cctaactcct tagcaatttc aacaccttca
    30601 ttagttgtcc atacaccttt tccttttggt ctatttatat ctagtctctc tagtaaatca
    30661 tcaaattttt ctctatcttc tgctgcatct atatctctaa agtctgttcc cagtataggt
    30721 atattttttt catgtaaaaa cttagccaat tttatagctg tttgtccacc aaactgtagt
    30781 attacacctt ctggtttttc tttttctatt atatttaaaa cttcttcttc tgttaatggt
    30841 tcaaaataca acttatcaga tgtatcaaaa tccgtactta cagtttcagg gttattgttt
    30901 acaattatag tttctattcc catttttctt aaagatttta cacagtgaac tgaacaatag
    30961 tcaaattcta ttccttgacc tattcttatt ggaccagaac ccaatactac aacttttctc
    31021 ttatcactaa ctactacctc atcatattgt tcataagttg aatagtaata aggtgataga
    31081 gcttcaaatt ctcctccaca tgtatcaacc attttataaa ctggttgtat attatataaa
    31141 cttctcaatt catataattt ttctgggctt atcttcatta agtcagatat acctttatca
    31201 gaaaatccct ttttctttaa ttcatgtaaa tattctttat ctaagtcttc tatttttaga
    31261 acttttaact tttcttcttg ttctactatc catttaaatt tatttataaa ccacttatca
    31321 acaccagtta tttctgatat catttctact ttatagcctc ttcttatcat ttcagctaag
    31381 tcaaatagtc tctcatcatc aggtactact actctagcct ttaattcttc taatgttcta
    31441 ccttctgatg gagcatgaac caatgaatat tttcctgttt caagtgatct tataccttta
    31501 agaatagcag cctcaaagtt acttcctata ctcatgattt caccagttgc catcatctta
    31561 gttcctaatt ttctattggc atgtctaaat ttatcaaatg gccactttgg tatttttact
    31621 accacataat ctaatgttgg ctcaaaacaa gcataagttt ttttagttac tgcattttct
    31681 atctcatcca aagtataacc taaagctatc ttagctgcta cttttgctat tgggtatcct
    31741 gtagcttttg atgctagggc tgatgaccta ctaactcttg ggtttatttc tattatcgca
    31801 tattctaaac tatgtgggtt taaagctatt tgaacgttac atccaccttg aacctctatt
    31861 gcatttatta tgtctattga tgcctttcta agtagttgat actcttcatc acttagagtt
    31921 tgacttggag caacaactat actgtctccc gtatgaactc caactgggtc tacattttcc
    31981 atattacata cagttataca gtttccattt ccatctctca ttacttcata ttctatttct
    32041 ttccaacctt ttatactctt ttcaagaaga acttgtccaa caggacttag ctgtagtcca
    32101 tgtgaaagta tttctcttaa ttcttcctca gtatcagcta tacctccacc agttccacct
    32161 agcgtatatg ctggtcttac aactactgga tatcctatct tattggcaaa ctcaagacct
    32221 gcttctaaat ttgtaactat atcactaact attactggtt gatttatttc tttcattact
    32281 tctctaaata aatctctatc ttcgcccttt tttatagatt ctatagatgt tcctataact
    32341 tttacattat atttatctaa tataccagca tcatgtaatt ctacagctaa gtttaatcct
    32401 gtctgaccac ccatacctgc aagtaaactg tctggtcttt ctttttctat tattttttct
    32461 ataaattcta ttgttaatgg ttctatatat attttatctg caatttcttt atcagtcatt
    32521 atagtagctg ggttactatt tactaataca acttcaattc cctcttcttt taatgcttgg
    32581 caggcctgtg ttcctgaata gtcaaactct gcagcttgac ctattattat tggccctgac
    32641 cctaatacta aagttttctt tatactatct aatttaggca taactctttc tccttatcta
    32701 aacaattttc acagttctta tcttcatcat ctatacaatc aactttaatt actttatttt
    32761 atcttaagtt caaatttact catcaataca tctatttaat acatctatgt taattaaacc
    32821 aaactttttg atttaagtta ttcttgtttt ttagttagct attctaatgt tgtttatttt
    32881 actaattcta aaaatttatc aaaaatatag tcattatctt ttggtcctgg gcaagcttca
    32941 ggatggtatt gaacactgta tacatctagc ttctcatgtc gcattccttc aacagtatta
    33001 tcatttaaat ttatatgtgt cactttcatt tgttcaggaa cttctgaaac ataataacca
    33061 tgattttgag aagttataaa tacttttcct tcttctaaat ctttaactgg atgatttcca
    33121 cctctatgcc caaatttaag tttagcagtt tttcctccaa gagctaaagc taaaagttga
    33181 tgtcctaagc atattccaac tataggtttt ttaccaataa gagcttttat attttctata
    33241 acatcttcta agtcttctgg gtctccaggt ccatttgaca agaatattaa gtcagggttt
    33301 atactcaata catcttctgg agatgttgta gctggaaata ttgttatatc acatccacga
    33361 gctataaatg atcttaatat atttcttttt actccaaaat ccataacagc cacttttgga
    33421 ccatttcctt ttatatgctc tacttctttt cttgtaacag ttctaactgc ttctgtattt
    33481 gaaaacttat ccaatttatg tttaacatct tctaatttac tgtcttctaa tgtaattata
    33541 cctttcattg ttccattatt tctaagtatc ttagtcaaag ctcttgtatc tattccttca
    33601 agtccgataa ctttattttg ctttaaatat tggtctatat caatttcaca tctaaaatta
    33661 cttggagaat cacttttctc ccttactatg aatcccttta cttgaacttt ttcagactct
    33721 gctgatgata aatttatacc ataatttcct acaagaggat aagtcatagt aactatttga
    33781 ccatagtaag aagggtctgt taaaacttca ccatatccta tcatcgaagt attaaatact
    33841 acttctccta cactttcttc taaatatcca aatgcctttc ctataaaaac tgttccatct
    33901 tctaatatta accttgcttt catactacag tacctcctat aattctcttt agacaaacta
    33961 aagaacatta actaaatata agcttttaaa tatctatatc tatttttcac ttttacattc
    34021 tagttttata cttatttaca tttatttttt atctttttct attatactac aaatttctta
    34081 aaaaaaagaa gttatctcaa aagtaaaaac tcctagaaaa aataacctct tttttttatt
    34141 taataattaa attcttaaac tatacaatca acttaatttc tattcagcta tattgtaaac
    34201 ttttaactca tctttattta aatgtttctt cttaacttct actaaagctt ttagtgtatc
    34261 caaagatgtc attatttcag tagaaaattc aatagctgtt cttcttatct taaatccatc
    34321 tcttgtagag tcatttcctt tagttggtgt atttattact atatcaactt gtttatttct
    34381 tatagcatct aatatgtttg gtctagattc ttctactcta tttactatat cagcctctat
    34441 tccattttct cttaagctat tagctgttcc ttctgtagca acaaaagtat atcctaattc
    34501 tttcatatct tttgctatct ctataaactc atctttatca tgattattta cagtagcaag
    34561 tactactcct ctttcatcag acatatgtct acctgctgcc aagaaccctt tatataaggc
    34621 ttcttctaaa ttttctccta cacctagaac ttctcctgta gacttcattt caggtcctag
    34681 acttacttca actttagata atttagacat tgagaatact ggtactttta ctgatactaa
    34741 ttttggctct ttgtaaactc ctgtaccata tcctaaatcc tttaatttag cccctaacat
    34801 acacttagta gccaagtcaa ctattggtac tccacttact ttacttatat acggaactgt
    34861 tctactagct ctagggttaa cctcaattat atataattca ttttgaaatt ctataaactg
    34921 tatattaacc ataccaagca cattaaggtc taaagctatt tttttagtgt attctactat
    34981 cttttctttt atttcatcag atatattttg acttggatac attgttgtac tatctccaga
    35041 gtgaactcca gctctttcta aatgttccat tataccaggt atcaatatat cttccttatc
    35101 acatatagca tctacttcta tttctctacc agttagatat ttatctataa gtactggatt
    35161 tttatggtct ctatcaaatg catcttgtag gtattgagat aatttttctt cgttataagt
    35221 tatttccata ccttgaccac caagtacata agatggtcta actaatactg gataacctaa
    35281 ctcattagca acttcaatac cttcgttaag tgaccataca ccctttcctt ttggtctatt
    35341 tatatctagt ctctctagta aatcatcaaa tttttctcta tcttctgctg catctatatc
    35401 atcaaaatca gttcccaata taggtatatt tttttcatgt aaaaatttag ccaattttat
    35461 agctgtttgt ccaccaaact gtagtattac accttctggc ttttcttttt ctattatact
    35521 taaaacttct tcttctgtta atggttcaaa atacagctta tctgatgtat caaagtctgt
    35581 acttacagtt tcagggttat tgtttatgat tatagtttct atgtccattt ttcttaaaga
    35641 ttttacacag tgaactgaac aatagtcaaa ttctatacct tgacctattc ttattggacc
    35701 agaacctaat actatcacct ttttcttatc actaacaact acctcatcat attgctcata
    35761 agttgaataa tagtaaggag atatagcatc tatctcacct gcacaagtat caaccatttt
    35821 atatgctggt tttatattgt atagacttct caattcatat aatttttctg gacttatctt
    35881 cattaggtca gatatacctt tatcagagaa tccctttttc tttaattcaa gaagatagtc
    35941 tttagttaaa tcttcaattt tcataacttt taatttttct tcttgctcta ctatccattt
    36001 aaatttattt ataaaccatt tatctatacc tgtaatttgt tctatcattt ctactttata
    36061 gcctcttctt atcatttcag ctaaatcaaa tagtctctca tcatcaggta ctacaactct
    36121 tttctttaat tcctcaatgc ttctctcctc agatggtgtg tgaactaatg aatattttcc
    36181 tgtttcaagt gatcttatcc ctttaagaat agcagcctca aagttacttc ctatactcat
    36241 aatttcacca gttgccatca tcttagttcc taattttcta tttgcttttt taaatttatc
    36301 aaaaggccat tttggtattt ttgccaccac ataatctata gttggttcaa aacaagcata
    36361 agttttttta gttactgcat tttctatctc atctaaagta taacctaaag ctatttttga
    36421 cgaaacttta gctattggat atcctgtagc ttttgatgct aaagctgatg acctactaac
    36481 tcttggattt atctctataa ctgcatattc aaaactatgt ggattaagtg caaattgaac
    36541 gttacaacca ccttgaactt ctactgcatt taatatatct aaagatgctt ttttaagcat
    36601 tgcacattct ttgttactta aagtttgagt tggagcaaca actatactgt ctcctgtatg
    36661 aactccgact gggtctatat tttccatgtt acatacaact atacaatttc cctttgaatc
    36721 tcttattacc tcatattcta tttctttcca accttttata ctcttttcaa ttaatacttg
    36781 tccaacagga cttaattgta gaccatgtga aagtatttct cttaattctt cctcattatc
    36841 agctataccc ccaccagttc cacctagtgt gtatgctggt cttacaacta ctggataacc
    36901 aattgtaagt gcataatcaa gacctgcttg taaatctgta actatatcac taactattac
    36961 aggctgattt atttctttca ttacttctct aaatatatct ctatcttcac cttttttgat
    37021 agattctact gaagtaccta ttatctttac tccatattta tctagtatgc ctttttcata
    37081 aagttcaact gctaggttta gccctgtttg tccacccata cctgcaagta aactgtctgg
    37141 tctttctttt tctattattt tttctataaa ttctattgtt aatggttcta tatatatttt
    37201 atctgccact tctttatcag tcattatagt ggctggatta ctatttatta atacaacttc
    37261 aattccttcc tctttcaaag actggcaagc ttgtgttcct gaatagtcaa actctgcagc
    37321 ttgacctatt attattggtc ctgaccctaa tactaaagtt ttctttatac tatctaattt
    37381 aggcataaat ttttctcctt atctaaatgg tttttactat ctgtaaataa tactaaatct
    37441 atattaatgc taagaattta ttaaatatac aatctaaatc ttcttttgtt gtgtattctg
    37501 gaatgtattg aacactatat attggtaatt ccttatgtct cattccttct atagtattgt
    37561 catttaaatt tatgtgagtt acttctgtat tttctggcat ttctgaaaca ttatatccat
    37621 gattttgaga agttataaat acctttccag tttctaaaca tttaactggg tgattacctc
    37681 ctctatgtcc aaatacaagc tttgaagtct ttcctcctaa tgccaatgct aaaatttgat
    37741 gtcctaaacc tattcctgtc aatggctttt tgcctattaa tttttttata ttttcaacta
    37801 tatcatttat atcctctgga tttcctgggc cattagataa taagattaag tcaggattta
    37861 tatttaaaat ttcttctact gtagtcattg ctggtactat agttatatca cagttacaag
    37921 ccttaagaga ctctagtaca ctatttttaa caccaaagtc tataactaca actttagctc
    37981 cagtaccttt tatattttca atttcttttc ttgtaacatt ttttactgaa tctttgttac
    38041 aatgctcttc taatttagac tgaacatctt gtaatgatac attttctaaa gttataattc
    38101 ctctcttagt tccattgttt ctaataattt tagttaatgc tcttgtatct attccttcaa
    38161 gtcctattac cttattttgc tttagatatg tgtctatatc catttcacat ctaaaattat
    38221 ttgggttatc acttttttct cttacaataa gtccttttac ttgcacctta tttgattcaa
    38281 catcttctaa atttattcca tagtttccta taagtggata agtcatagta actatttgtc
    38341 cataataagt tgcatctgtc aatagttctc catacccagc cattgaagta ttaaatacaa
    38401 cttctccaat agcttccttt agatatccaa atgcttttcc ttcaaatact gttccatctt
    38461 ctaaaattaa tttccccttc atgtaagcta cctcccaaat attttatcta agcattttct
    38521 atttctctta caatattaat agctgattct cttggatttt ctgcttttgt tataggtctt
    38581 ccaacaacta aataatgagc accttttttt attgcatctg atggagttac aactcttttt
    38641 tggtctccaa cctctgctga tttaggtctt attcctgggc aaactgttat aaaatcagtt
    38701 ccacatgctt ctactatttt atctacttct tgcgctgaac aaacaacccc atctattcct
    38761 gattcttttg ccagtttagc tctctttata gctaactctt ctgttgtcat attacatcct
    38821 atgtcctgta aatcttggtt gcttaatgaa gttaaaactg ttactccaac tactaatggc
    38881 ttttctatat ttaatctttc tgcttcttcc ctagcaatta gtgcacattg tctcattcct
    38941 tccatatctg atacatgtat tgtcattaac caaacattat ctctcactgc agctttcact
    39001 gcacttttca tagtatttgg tatatcatgg aatttaaggt ctaaaaatat ttttttccct
    39061 ttttctttaa gataatctat tgttttacct tttgtggcaa cgtattgctc tagccctacc
    39121 ttaaatatgt ctacactatc ttctaatctg tctattagtt ctttagcttt atcaaattcg
    39181 tcagtatcaa ttgcaactat caatttttct ttaccattta tcatttttac atctcctttt
    39241 taataaagcc taaataatca taaaaaaatc ctcacaccaa aagaggcata aggattttat
    39301 ctatacataa ctctattcat tagctatgag atatctttcc cagtctctct ggactagttt
    39361 aaaagacttt attatattta aatttttatt ttatactcat caaaaacctc tagaagattt
    39421 actagaggtt atatactaac attatctata accctttagt ctctctggac tactttaagg
    39481 aatttagctg taatattttt ctttatttat ataactttat gtatctatag gataatttaa
    39541 agttttatct tttttataat taaaccacta attgcttttt atgtcaataa gtctttgaat
    39601 tattcttcat ctttatcaaa caattttttc tcaaaatatg attctgcatt atatattgca
    39661 gcaactggat tatgcccagt tactctatct ttgacaacta aagttgttat aggagcttcc
    39721 atatatttca tggctaaagt atcgtgacca acacataatc caagaattac attaaggtca
    39781 accttagctt catttaaaaa taaagcttgt cctattggat tgcacattac ctcatctgaa
    39841 cactttgata ttgtttgaga tgcttctagt ccaattgtac tcttaggcat tgccccattt
    39901 ttacatataa cagaaaatac ttcaaaccca tgatgttcaa atattttttg cactgtttgc
    39961 atttctcttt ttagtccaat acaaaatgct atgccaatct ttttataacc acacttttta
    40021 gcaaactcta taatctcttt tagtctagta tattgacaat acccctctgc ttcaactaat
    40081 ccagcattat aagctatttt tctattctct tcttcttcat aaagttgctt tgctttttgt
    40141 tgtagttcaa tttctctagt tggacatatc ttcattaatt tatccatatt tccattagaa
    40201 cagcctctaa gattacattt tccacactta tacatatcca atatcccctt ccaaaatttt
    40261 attcatcttg cgattcttct ttttctagag ttacattttc ttcttgggtt tcttcttctg
    40321 gtttcacatg ctcgactaca gttataaaat atgattttcc tattttattc cttataggaa
    40381 gtttttcata tgaaacatct attttatttt ttatacaagc tatatcaaaa tgtcttaagg
    40441 ctacacctaa gctaacctta ttcatatctt cacagtgttt cttaggtctc ttttcaaata
    40501 aatgaagacc tcgttcatcc ttatggaaat accacggttg agaatttttt acagatggag
    40561 ctcttcttgt caattctaag atatctttcc actttctatt cctatttatc ttatttatca
    40621 tatcttttac tggctttcta tcaggtctag catatctcgt cctaaacaac tcttcatttt
    40681 ttgctggata tccaaatgct attattatat aaggattttc tattttgttt tcatcatctt
    40741 cttctgtttt tattccagct agataatcta aatcatcttc ctcatcttct tcaaaattct
    40801 tattcccaat atctacaaat tccaagatat cttctctctt taagtttcct tccaaccagc
    40861 aagtagctat tcccaatgtt gtaaggcgca aaactacacc ttctgtagca aatcctatat
    40921 tctgtaaata gtcctcacct ttgtctgatg taactactat ataatgaggt gcctttactt
    40981 tacattcctt ccccatcaaa aaatgtatta tatgacctct atcaacaaca tgtgctttaa
    41041 tatttaaatc ttcatttaag tattctaaat ttttacaact tctttttatt tcttccatca
    41101 atggcttttt tatcttttta ctggaaaaat ttcttacaga ttttctataa aaaatggctt
    41161 cataaagctc catttatgcc ctcctaactg aaatcttctg acgtataaac tctataaatt
    41221 tatataaata ctttatattt tttatagttt tatttccttt ttcctcctgc cctattttga
    41281 aattcataag aatatctact ctagtttaat atagcattca aaaggcttaa attctacctt
    41341 atcaatgtct atacattagc ataatttttt tatttgattt tctatgctaa tttaaataac
    41401 aacactagct attacctttt taattaagct ttgccagaaa aatttttttt catttataaa
    41461 tatctatctc attattatat tataagtttt tttcggtatt cttgtatagc ttttcactaa
    41521 aaaagtattt ttatttctac tttaatatta ttatcaacaa aaaacatact acttaaataa
    41581 gtttgttatc ctcataattt gttttaatta aaatattttt tttatttctc aatctataaa
    41641 gtataaatat tttgaatatg acccaaaatc taagtaaagt tataatattt tataagttgt
    41701 tcaatattaa aaacataagt aatgttataa tactttataa gttattcaat attaaaaata
    41761 taggaggata aatatgaatt taaatagaaa tttagaaaaa tacgctgaat tagcaataaa
    41821 agttggagtt aacatacagc caggtcaaat tctacttata aagtcaccaa tagaatgtgc
    41881 tgattttgca agaaatgcac ttaaagaagc atataaatgt ggtgctaaaa atgtttatat
    41941 agagtggtct gatgaagaaa gtactcttat taaatactta tatgctccag atgaagcatt
    42001 tcatgagttc cccaaatgga cagcagaaca atatgtagat atagcaaaag aaggtggggc
    42061 atttttatca gtctatgccc aaaatccaga tttattaaaa gatgttgacc ctgaaagagt
    42121 tgcaaatttt cagaaggcat ctggaaaagc tttaaaagaa tggcgttctt acactctaac
    42181 tgataaatgt aaatggagta tagtctctgt gccaacaaaa gattgggcaa aaaaagtgtt
    42241 tccaaattta tcagaagata aagcaataga aaaactgtgg gatgctatat ttaaatgttc
    42301 aagagtagat ggtcaggacc ctataaaagc atgggaagaa cataatgaaa atcttaaatc
    42361 taaaatggac tttctaaata aaaataactt taaaacttta aaatataaat cctcaaaaac
    42421 tgatttgact ctagacttgc caaagggtca tgtttggcta agtggagcat ccaaagaccc
    42481 taatggaata agttttaatc cgaatattcc aactgaagag atttttggaa tgccacataa
    42541 gtttaaagta aatggaactg tttatagtac aaaacctctt gtttatggtg gaaacataat
    42601 tgacaatttc ttcttaacat ttaaagatgg taaaataata gatttctctg ctgaaaaggg
    42661 actagataca ctagaaaaac ttattgaaac ggatgaaggc tctcattatt taggagaagt
    42721 tgctcttgtt ccatacaact caccaatatc caatacggat ataatttttt ataatactct
    42781 atatgatgaa aatgcttctt gccactttgc aattggttct gcttataaga cttgtctgga
    42841 aggtggaaac aatttaaaag atgaagaatt agatgaacat ggtgtaaatg acagtttaac
    42901 acatgtagat tttatgattg gttctgctga tatggatatt attggtgaga cttatgatgg
    42961 aaagcaaata cagattttta aaaatggtaa ttgggctttt taacatatga ttttaactaa
    43021 aaagggctga tggaagttat accagacttc ccagcccttt ttaatgttga tgataaatat
    43081 tttttatatt aattaatctc attattatag attaattcct attgttttaa acataagtat
    43141 ctaaaactta tatttatatt atatataaaa tatcctattt agtaaaacct ttattttaat
    43201 ttatatgcta aaaatttaac tttgctattt caacagcaga ctttgcatcc tttgaataat
    43261 aatcagcacc catttcttca gcgtattctt ctgtcaaaac tgcacctcct acaaatacct
    43321 ttgcatttat ctcattatct ctcagtgcct gaattgtatc tttcatactt tgaacagtcg
    43381 tagtcataag tgcacttaat cctactaatt ttatatttct ctttttagca acttccacta
    43441 cttcttcaat agggacatct ttacctaaat ctataacttc atatccataa ttttctagca
    43501 ttatttttac tatatttttc ccaatatcat ggatatcacc ttttactgta gcaactatta
    43561 tttttccttt ggatacatta ttgctacttt tacttaataa agtttccttt attgtattta
    43621 atgaaacttt taccgtttct gctgattgaa tcaattgtgg taaaaatata tctccactat
    43681 catatctttt tcctacttta tcaagagcag gaattaaaat ctcatctaat atataatttt
    43741 catccttctc ttttaaaaga ttcagtgtta cattttttgc ttcatctttt aatcctcttt
    43801 caactaaaat atccaagggc aaatctttat caatctttgt agatgaatcc gatttttttg
    43861 aattatttat attgctatat tgatttatat agtttataca tcctttatct gtgttattta
    43921 atattttaaa agaattgata gcttccatca tactatattc atttggattt ataattgcta
    43981 aatcaagccc tgcccctaaa gctaatgtta gaaaagaagc attaagtgct ttcctatttg
    44041 gaagaccaaa tgaaatattt gaaacaccta atatagtttt tactcctagt gtctttacca
    44101 ttgttatagc ttttatagtt tctattgctt cttcttgttg tgctgaaaca gttaatgata
    44161 aacagtctat aaatatatct tttggtttta tcccataaga aactgctcta ttaactatcc
    44221 tttttgctat ttcaaatctt tcttcagcct ttttaggtat ccccttttca tcaagtgtaa
    44281 gtccaaccac acatgaacca tactttttaa ctattggtaa tatactttct aaagactcct
    44341 ctttgccatt tacagagttt actattgttc taccattata atatctaagt ccttgctcta
    44401 aggcctctac attggaagaa tcaacttgta aaggtgtatc tactactgct tgaatctctc
    44461 ttattaattt tggcattagt tttttttcat caatctctgg aagaccaaca tttactccaa
    44521 gtatttgtgc tccagcattt acttgttcta aacctaaatt tatagcataa tcaacatttt
    44581 cattttttaa tgcttcttgt agagattttc tacctgtggg attcaatctt tctccaacaa
    44641 ctgtaggcga ttgtacttcc acaaattttg atggtgaaca gactacacat ttatcaattt
    44701 tctcgataca tccctttgta acagaattta tattctcaga tatttctttt ataaaacttg
    44761 gattcgtacc acaacatcca cctattatag tagcaccaac ttcaacgaac tttttaaccc
    44821 cttcaaaaaa ttcttttgca tcaacatcat atatagcctc tccatcaact atatttggaa
    44881 gacctgcatt tgcttgaacc ataacaggga ctgtagctct tgatgctatt ttttcaacta
    44941 ttggtaaaag ttgtttaggt cctaatgaac aattaactcc tattgcatct acacctagac
    45001 cttctatagt agccaccata cattctggca tacatccagt aaaacttctt ccaccttcat
    45061 caaatgtcat agtacagaaa ataggtaaat cagagttttc ttttgctgct aatacagcta
    45121 ctttagcttc atataaatcc atcatagtct ctattactat tacatcaact ccagatttaa
    45181 cgccttgtag tacttgtctt ttaaatattt catatgcttt atcaaaactt aaagtaccca
    45241 taggctctag catttctcct ataggaccaa tatctaaagc tacatatctt ggtttagtat
    45301 tatctacatt ttctatagct tttctagcca ccaaaacagc attgtcaatc acttcttcta
    45361 cagtatactt actatctaat tttagttcat tacatccaaa agtatttgta agaattacat
    45421 tcgaacctgc ctctaagtat gctgtatgta tttctataag tttatctgga ttttgaagac
    45481 caaatacttc tggattttca cctaacttta accctttttg ttgaagcatt gttcccattg
    45541 caccatcaaa tattaatata ttatttttca gatattgtct tatttccaca agagttcgct
    45601 ccttttctat atgtacagtt tctatagttt ttacaatttt cacacgactt ttctttctta
    45661 gatttattta ttcttgtatt agaaatacct ataatagcca ctactgactt tctcggtatc
    45721 ataattccat tagaagtaat tgttagacct atttgttttt gagcattcaa aacgtttaat
    45781 atatctatat ttttttctat tggtaaatct ccatatcctg ggctatatcg catagttata
    45841 aatttatctt gctttaaaaa aaccttttct aaattatttt gaacaatgtc acacacttct
    45901 tctattgctg ttgttccaca tgaatcaatt attagtcctt ttgttaaatt tgaataagag
    45961 tgtcgtctta tttctttttc tatatctatc cctatagtag ctgccataat tacacactca
    46021 ttacattctt ttaaaagttc atatacatct ttactctcta atgttaaatt tgttccctct
    46081 aattctacaa cattatcttt atttatttta ataggataaa tcctagataa atatctagga
    46141 tttattttat ttttagttat agctacacat tcatcaatag tatatttaag gtctttatct
    46201 atctcttgac ctctatattg taaatatctt aaaacttcac tttgatttat gcttatatct
    46261 tctcttccaa ttaaattatt ctccatatat atttaaagaa aatcctttat ctaaaacatc
    46321 ttttgcatat tcctttgccc caaataaaga taagtctctg tagtttccac attctatagc
    46381 tgtagctgct ggcattttat ctgattcaag aacttttttt aatgcttctt ctaaaccaat
    46441 cttaactgtt ttggcatcta catctcccca tagtattaaa taaaatcctg ttctacatcc
    46501 cattggagat aagtctatta caccatctaa tgtatctctt aaataagtag ctaaaagatg
    46561 ctctaaaccg tgcatagcag cagttccaaa actttctaca tttggctgta aaaatctcaa
    46621 gtcaaattta gttactttat ctccctttac tccatcaagt acactacact ttcttacaaa
    46681 aggagctttt acttttgtat ggtctagctt aaaactttct actttttcca ttatttaatc
    46741 ctccattata ctttaaaatt tgttacatta attctaaaaa aaactcttcc tatctattat
    46801 tgataagaag agtatattat ttcaagtcat ctcatcgttg ttagcaggac cacctgataa
    46861 aaggttggta taggatcact gagctaactc tctcccctaa ctcttgataa gtatcttatt
    46921 aaactgactt aaattatata ttactttttt atttttgtaa acactttatt gttataatat
    46981 ttatatcaca taatcgtact tttattttat aactaagctg attgtattat tggcagttgt
    47041 acttcaaaca cagtttgata tttatcgctt gaaacagtaa tttctccatc atgtaaattt
    47101 acaatatttt ttgtaatcgc aagacccaat ccagaacctc caacatttct atttctcgat
    47161 ttttcaactc tataaaatct atcaaatata tttggtaaat ctaacactgg aattggttcc
    47221 ccataattta tcacttttac aaccgccata tcttcctttt tctctgtgac tatatctaca
    47281 taatgcccat cttttccata tttcacagca ttagttataa gattttcaaa tgctcttacc
    47341 aatttatttg gatcagcttt tacaattaat ttttcttcat taaaattaat tctactaacc
    47401 ataaattctt gtttaaaata aatttcaaat tgagatacta cttgacttaa taactctact
    47461 aaatttattt ctattttgtt taattttatt gtattatttt gcattttagt caattcaaac
    47521 aaatcattta taagaacatt taaatttttc gatttttcat atgcaatatc aacataatac
    47581 atcatctgaa cttcatcttt atacttacct tcttctatca ctcctaaata acccattatg
    47641 gatgtcaaag gtgttcttaa gtcatgtgac acatttgtta ttaaatctgt ttttgtctgc
    47701 tgagcttgtc tctcttcaat agttatattt ctaagttgat ggactatatt attgatttta
    47761 tgtgctagtt catcaatatc atccttttct ttatccttta atatatctaa atcatactca
    47821 atatctatac ttttttctaa gttaccttca tccattaaat ttacagcact tttaatgatt
    47881 tctaattttt gattttttct attagtcttt cttataaaat ctacaatttg cttatttctc
    47941 ttgtacgata tcatggaata aattgctaat gatgtgattg taaataaaaa tggataaaat
    48001 aaatcatacc ctataagact tctgaaatct cttgcttgat atacaagttg attaactaca
    48061 gacatatcac tattgacata taatgatttt attatataca tacttgttaa aataagcatt
    48121 gaagttaaag cacagcttat tataagatct aatatgggtc gaaacatatg atttaataaa
    48181 cttttatttt tcaattttat atcctactcc ccatacagta tgaattattt tttctccatc
    48241 tgtatatttt tcaattttat cccttattct gctcatatga accattacag tattattaga
    48301 ttggtaatat ttctctttcc ataccttttc aaatatttct tctgtactat atactctgcc
    48361 tttattattt gctagtaaat ataatatatc aaattctctt gatgtcaaaa ttatttcatt
    48421 tccagccact gttacactat gtttttcctt atctataatt actactccaa cctttatgac
    48481 atctttatct tcattattag caccactaaa ataatatgct cttctaatca gcgacttcac
    48541 tctcacagta agttcaagtg ggttaaatgg ttttgtcaaa taatcatctg caccagtcat
    48601 tatcccttgt attttatcca tgtcttctga ttttgcactt aacataagta ttggtatatt
    48661 caaactttct ctaacttttc tacaaacttc tatcccatcc attttaggca tcattatatc
    48721 caatatcatt aaatgaatat tttccttttt taaaatatct agagcctctt ttccatcttc
    48781 agctttaatt acattatatc cactatttaa aagatatatc tctataaggt ctcttatttc
    48841 cttttcatca tccacaacaa gaactgtatt attcattttt acacatccta acttaatctt
    48901 tgtatatagc tttattcata taaaattata ctatatttta gttagtgtaa tctataaatt
    48961 tattaatttc taaatttcca atataataca aattatttac acatttatat tatttatttt
    49021 gtaaatattc ttctaaagtt aatccttttg aataaatttc ctcggcagca tccttaccaa
    49081 catatctaat atgccatggt tcatatgctg tacctgttat atcttcttta ccttcaggat
    49141 atcttattat aaatccaaac ttgtgagcat tttctgccaa ccatttagct tcttttgtac
    49201 ttccaacaaa ccatctttct ggatttgtta aatcaataca aagtccagtt tggtgctcac
    49261 tgtaaccagg ctttgctaca tacgcatctg ccttttctcg cccctgagat tttacccttc
    49321 ttgtataagt atccagttga gtatcataag atctgtatgc tgaagaccct aaaaactgta
    49381 ttccttctga attagcttgc ttaactaaat cttcaactgc ctttgcaggt tctcctgcca
    49441 tttgtttttc ttcctctgtt gcttcttcaa caaaaggtat gtttacctta gtaatatttt
    49501 caggagtata gtttttgcta attccatttg tcttgtttac caataatata tttgatatac
    49561 tatttgagtg atttttattt tgagaatttg cctcaacatc ttgttctgaa tcatgttgag
    49621 cagctactat tggatcttta tctttcttaa gtaatctatc tttagatata aatacactta
    49681 taaatactac taaaataatg gctcctatta atttaaattt tttcataatt aaatcttctc
    49741 ctttttgtta tgtttgctat aatgttaatt ttagagtata agacttaagt attttataag
    49801 taaatcttaa ataaatctta aatttaatat ttttaaagga tggtgataaa atgtctatac
    49861 aaaaacttct aagtaaagct cgtaaggcta tacaagattt tgatatgata caagaaaatg
    49921 ataaaattgc ggttggactt tctggtggaa aagatagttt aactctactt catatactta
    49981 aaagttatca aagattttct ccacaaaact ttgaattgat agccataaca ttaaatactg
    50041 gaggtgttga taattctcca ctagataaat tgtgtaaaga aataaatgtt cctttttatg
    50101 aatttcaaac tgacataaaa gaaattgtat ttgatataag acaagaaaag aatccttgtg
    50161 cattgtgtgc taatttaaga agaggtgctt tgaacgataa tgctaaaaaa cttggatgta
    50221 ataaagtagc tcttggtcat cataaagatg atgcaattga gacattttta atgtctatgt
    50281 tttatgaggg tagagtaaat tgtttttccc caaagacata cctagacaga caggatttaa
    50341 cagttataag acctatggtt tacatagaag agtatatgac taagaaaatt tcaaaagatt
    50401 ctaactatcc tattatcaca aatccctgcc ctgcaaatgg tcatactagg agagagtaca
    50461 taaaaaatct tattgctaat ttaaataaag agatgcctga ttttaaaaga aatgtatttg
    50521 gtgctttaaa taattctgag aaattgttta tatgggataa agagaagata aaaaatttta
    50581 aataataatt aaaattttta aataaaaaag caagattgta ttaattgtaa ataatcttta
    50641 tataatctac acaatcttac ttttttattt attatatgtt attatcttta atctatattt
    50701 taatagttct taatagtatt tattttgtct aatacattaa ttataactta aatattttat
    50761 atattaattt aatctattaa ttcattcaat ctactggttt aatccatttt tacagtatat
    50821 acatctacat attataaaaa gcaaaattat attttctaaa tattttatgt tagattataa
    50881 tattaaattc tattatctct ggtatattaa aaaatctaaa tggtaacttt gtacttccaa
    50941 gacccgaact cacatataaa tgatttccat ttatgtcata aaacccttta gtatatttcc
    51001 ttccatatgg aggagtaact aatgctccct taataggtaa tcttatttga ccaccatgac
    51061 tatgcccaga tagaactaaa ttcattgtat ctttactaag catatctact aaatctggtt
    51121 catgtgctaa caataaatta aaacttttat tatctatttg actctccaga tattttatat
    51181 taggatttcc atttaatatt tcatcaacac ctaatatatt aatatattta tcatctttta
    51241 attttatttt tttattttca tttactaaaa gattgaagtt ggaatttttc ataatctgcc
    51301 tataatacct aggaagttta tacatataat catgattgcc aaatactgaa aattttccca
    51361 acctagcatt catacttgat aaaatagttg taatttcatc tacacttgga tttttattgg
    51421 agtaatcaat taaatcacca gtaaatacta ttatatctgg attcaaagtg ttaatcttat
    51481 tagctacttt tttgagattc ttagttgaat aaaaactacc tatttgagta tctgaaattt
    51541 gaactacttt tacactttca gatttactct caattgaatc attttttatc aatgctccat
    51601 tttcacttat attatatttt ttcacaatta atagactcgg ctctatcgca actgagtata
    51661 taaaaatcaa aataaatatt aagataaaaa attttaaaaa atacttaatt tttgagttca
    51721 aaatatctac ctacttattt atttttttaa actatttgca ttacagactc aactttgttc
    51781 atttttctgt catgcatttt tggcttattt gctgaaaacc atttatatgt tgctgtaaga
    51841 ccttctttta gtaacacgtt tggtatataa agcccatgtt caataagctt atttatatca
    51901 agattaaagt ctatatttct aaatgggaaa tacgttcttt ctctaaactc tactttttcc
    51961 atatctacat attttattat aggttctttg ccaataattt ctccacatgt atatataagg
    52021 tcatcccaag aaattaactg tggatttgtc acattatagg cctctcttac atgaggattt
    52081 ttcattatgc tttccaatac ctttaccaaa tccccaatat atataaattg attactaact
    52141 tgttttcctt ttggtactgg tatcttttca tttttttcta ttttttcaaa gaaataatac
    52201 tctctatata aattattatt ttcaccatat atgtaagttg gtctaataat tatatatggt
    52261 atagggctat ttataataaa atcttcagcc tcttttttat ttaacccata ttttccccag
    52321 ttttcatttt cacctttctc attttcttct tttatatttc ttccactatc tttatatact
    52381 gctcctgctg acaatactat atactttttt aagttatcca tgcttataaa atcaatcaga
    52441 ttacttacat cttcttttgt atatgctgtc atatcatata tgtaatcata ttttcttcct
    52501 gtgataatgt tttccatatc ttttcgaact tttctatcac aaattagatg ttctttaaaa
    52561 ccattataat ctatttcctt tttaccattt gtaagtatat caatttgata cccacattta
    52621 atcaagcgct tagcaagtgc agaacctatg aagtcgcttc cacccataat taaaatagat
    52681 ttcattttaa gtgcatcctc ctctttttta aatgacttcc ttaactataa tatcatattt
    52741 ttaaatatgc gacaccattt tgtaatattt ttgtctataa aagatattta taacaaaata
    52801 tcttttatag actctacatt ttcgacaata taagtaggtt cactttcact aatctcttca
    52861 aaagaaccat acccatacaa tactccaata gaatctatac ctattttttt agctccaatt
    52921 atgtcatact ttctatctcc aaccataata actttatctt tatcttttac attacatagg
    52981 tctagtacat attgtataac ttcattttta ttcactcttg taccatcaag attgctacct
    53041 gctatatatt taaaatatct atctatatca aaatatctaa gtatagtttc tgcaaaaact
    53101 gttggcttag aagttgctac taataatatt ttaccatttt tatagagcat ttctaatatc
    53161 tctttcatat tctcataaat tttattttca aatatccctt tatcagcaaa atattctcta
    53221 tacttttcaa cagcttcttt agctttttta tcttcaaatt tataatactc cttgaaagta
    53281 tcatgtaatg gtggtcctat aaattggtct aagttttcca aatcttcttt tatgccaaag
    53341 ctatttaaag aatactgaat agactttgtt attccttctt tagggtctgt aagtgttcca
    53401 tctaaatcga ataatactat ttcataattt tttttcatat ttcagtcctc catatttgta
    53461 aaaagtaata tcttatatat taagtttatc tattttaaaa agctatagta atagaaattt
    53521 ctaatactat agcttaagta ccaattaaat cttatatatt tattttaaaa ataaatttaa
    53581 acagctctat ttaactgtta tagctgaaac tggacatcct tcttcggctt ctttacataa
    53641 atcttgtaaa tctgctggta tttctccttc aattgctact gaatgccctt catcgctcat
    53701 actaaaaacg tctggacatg ttcctataca tgctccacaa gctacacata catccttatc
    53761 aacaaatgct ttcatactaa aatacctccc ctaaaattat tattttttaa ttgttgtttc
    53821 cttagatatt tatccaatat ataccaattt aaacatatat ttattatttt atcactattg
    53881 tttagtttat tatagtattt tcgtatccat gtctataaac ttcactgctt ttcatccatg
    53941 attttacagt atattgcaat cttaattttt tatttaaaac aagttcatta ttattgtagt
    54001 cttttataat atcattacac tcctccattg taaatattgt aaaatcacct tctccaccaa
    54061 tctttattct gcctttattt ccatgtaaat cgaaaatctt tgttgggtat tcagttactt
    54121 tttctataca cttttctagg gatatcccaa gttccataat tttatttata acatttaaaa
    54181 gagaatagtt tacgtctttc atgtttttta tatgcatatc agtacttatt aggtcaggct
    54241 ctaaaccttg ctttattgct tttttaaaaa ctttaaaatc aaattggtcc actccatgac
    54301 atacatcaaa caatactcct ctattctttg catttattac tgattttctt aatgtgccag
    54361 attctttaag gattccattt gtactatttc catataccgg tgtaaccaca tctccttttc
    54421 ccaaaatatt cattacttca tctatatatg atggatactc tcctatatat accactaagg
    54481 gtaaatttaa ttttttagca acttgctttg atttcttaat tatatctata ccactttcat
    54541 tagattgaaa tttactcgct tttactttta taccctttat cttttctata tttttttcta
    54601 caattgactc aaccttgtca aaatttataa catctaaata agttgattca ttcaatatat
    54661 ttagtccctc atttgtaaca tttaaaaaag aatatacttc tgttttacac tcatccatat
    54721 actttttttt aaaatcatag tagtttgagg gaccagctgt acctgcatca aatataactg
    54781 tagaaccttt ttcaattcca attgaatcag aatccatacc tgtaggtaat tttctcttat
    54841 aacaatgggt gtgaacatct ataaatcctg gggaaatata catattatcg gcatttatta
    54901 tctcgaactc tttatttgta agtaattttt cttttcttat tttctcttta aggttcaatc
    54961 caatagcata tattttccca tgtaaaacca agatatctct tttttcaaat ttgataccat
    55021 ctgttggaga tattattgtc ccatttctta taagtaaatt tttcatttat tccacatcct
    55081 aattacaata taatttctct aatagctttt cttacataaa gaaaataagc ctaaaaataa
    55141 aaatatttta gacttattca ctatattata ctatattaat tatattaaat taaataaaat
    55201 ctttaattta ctttaagaag caattaagta tttgttgctc ggcttcttct tcagtaagac
    55261 ctaatgtcat catctttagt atttggtctc ctgcaatctt tccaatagct gcttcatgta
    55321 ctaaaagagc atctggatga tttgcagcaa tttcaggtat agcactaatt tgagaatttc
    55381 ccataattat tgaatcacat tgaacatgtg cagaacaaag ggaatcccca ataacacaag
    55441 gattaaactt ttgcttagaa ttatcttgcc caactgtacg agaaactact tgagcagaag
    55501 agttttcacc ctctaagata accttcatat tagattctgc aacttgatta ccatgagtta
    55561 ataatttctc aaatacaact attttagctc ctttacctag gtttgcatcc atttctcttt
    55621 tagttgaatc tacaccctta atttgaattg tttccatttc acaatatgaa tcctcatcca
    55681 tattgacaat agtaactgga tttaaaattc tctttccttc tccatcacct tcaccataat
    55741 gtttttctac atattttagt cgagctcctt tacgtaagaa aaatctatgt ataccattat
    55801 gttcactatc atcacaacca cagttatgta taccacaccc agcaattata acaacatctg
    55861 cattttctcc aatttcaaaa tcattatata ccatatcctg tacaccagcc tctgttacta
    55921 ttactggtat atgtacattt tctccttttg tatttggctt tactataata tctattccag
    55981 gtttatcagt tttaggaatt atagttacat tttcagttga atgtctctct actccttgcc
    56041 catttttacg tatattgtat gctcctaatg gagttccacg aagttcagca actttttcta
    56101 aaagatttaa atctattttg ttcatttaat ttgccttcct ttctaattaa ttcatgtctt
    56161 tcattaattc acaacttgaa ttaacttgac acatgatttc aggtaatata gcctcttttg
    56221 ttccatggct ttttactgaa ccatcttgta gaacaattat ttcatcagct aactctaata
    56281 ttctttcttg gtgagaaatt atgattatag tctgattaga ctcttcatgt attttcttaa
    56341 aactttcatt gagttttcca aagctccaaa ggtctatccc tgcttcaggt tcatcaaata
    56401 tagaaacctt taaatctcta gcaaaaagag ttgctatctc aattcttttc atttcccctc
    56461 cagaaagaga gttatcaact tcacgattta aatagtcttt tgaacacaat ccaacatctg
    56521 taaggtattg gcaacataca tcagtagaca atggttttcc atgagcaagt gtaagtaaat
    56581 tttcaactgt catacctttt attcttggtg gttgttgaaa tgcgtatcct attccttttt
    56641 ttgctctttc tgtaatacta agatttgtta tatcttctcc atctaaaatt atctgaccac
    56701 tcgtagcttt ttcaattccc ataataagct tagcaattgt agattttcct ccaccatttg
    56761 gacctgtgat aacaataagt tttcccctct caaatgaaag gctaacatca tttattattc
    56821 ctagttcctc attgttagac tcaacattaa aggaaagatt ttttatttca agcataatac
    56881 ccctcttttc tataaaatat tacattaata tccattcttt tattatatca gtaattttta
    56941 tatatcagca actctaagga gataaaatgt atattaaata ataaaacaaa gttattgaaa
    57001 agtaaaaaag atgagtttta tgtaaactca tctcagaaat ttagtatatc aacttatatg
    57061 tatttaaaat ttaaccttct atatactcta atattatttt ttgattatct tttaacataa
    57121 tttcttcttt tttagattct attccattct tttttatctt tacctcagct acaaaggcat
    57181 cattaccttc aaccatttct aatagttcat acgctttttt acgacctatt ttagttgcta
    57241 tatcttttag tactgccatt ttcttaaaca ttttatcacc tctactcaaa atttacactt
    57301 aatttttaat tatataattc taatcctaga ctagtttata ataattattg tctctaatta
    57361 tatcagatat tgagtaaatt taatactttg taaaattatt tatcctctct gaccaaataa
    57421 tcatttccat cttggtcttt aaaagaaaac atccttccat atggcatctc cattaattcc
    57481 ccaacctcaa cctcgttatt tgccatttgt tcataagttc cattaatatc tcttgtactt
    57541 aaaattattg atggatgaga tacatttatc tctttgtttt gcttcatcat tagattttta
    57601 tcatacaaca caaatgttgt aaattcattt ttacttggtg ctacttccac ccatttcata
    57661 tttggaccca tttccttttc ataagttact acaaagttca atttttctgt ccaaaataac
    57721 tttgcatcct cttgattatt tacatagaga gttatttttc ctattttatt tatcataaca
    57781 atacccacct ttattattaa ataaatacct aatatttttt atatttaata atatacccat
    57841 atatattatt ttctatagat atatatttct aatatttatc gccaaattat gtaattctgc
    57901 tcaatatata atttataata tccatactat tatagccttt atttatgtaa tttaatcacc
    57961 ttatatatca tacttataat tatgataata actacataaa aaatcacttc taaatagagt
    58021 tatccatcta aaagtgattt catatattct atgcaacttt gtgttttagc cactttgttc
    58081 ctcttaatct taaacaatat aaagtccctc taacaagcca atcagtatac atacctatcc
    58141 aaattcctaa cactccaaat tctaatacaa cccccaatac gtaacctgta aaaattctaa
    58201 aaatccacat acctattact gcagtcatca ttgtatatct agtatcaccg gctcccttta
    58261 gccctgctga taatacaaag gatataggcc atattaccat agctaaacaa tcacttcgaa
    58321 ttaattgtgt tgagatgtca attacactag cattttgagt atacatactt gaaatccagg
    58381 gtgcaattgg tataaatata gctcctacta taaataaaca aattgttgca aatttagtta
    58441 aatataataa agtactctta gctcctttaa tatctccacg tcctatatac tgtcccacca
    58501 aggttgtagc agacaaagct aaagcattcc caattacatt tattatggat gcaattgaca
    58561 ttcctattgc attggatgca attgctgatg ttcccatagt aactataaat acttgaacaa
    58621 tcaatttacc tgcattaaaa agtagttgtt caactccagc tggtattcct atattaaata
    58681 tagacttttg agtttcaaca tcaatcttaa atggaaatat tttacccata gatataaatt
    58741 cgtttccttt aaataaagct cttataatta ctatacatcc aattattcta gctatagcaa
    58801 tagatatagc tgcacctgtt atgccatagg atggtgtttg caaatttatt cctagaggat
    58861 ttaaatcaat accatatata agtatatatc ccaatgttac atttactata ttcataaaca
    58921 tagtcacata cataggtttc tttacatctc cacaccctct taaaatacca tttgctattt
    58981 gttgtgtcgc aataaatgga tacgtaaata atgtaaactc tatgtataat tttgcatttg
    59041 attttaccaa ttcttctgcg gaaccataaa ataaattaat tacaccagtt ctaaaaaccc
    59101 acatcaatat tgttattgta aaggataata ttactccaga cactagagcc tgcttaatag
    59161 tttcattcac cttttcacta tctttttttc ctatttgttg agctacaaca acagtagctc
    59221 caacagatag tgcagcaaat acagatataa atatattgtt tattgaatca accattccaa
    59281 ctgcagatac agcttcttcc ccaatatgac ctgccatcat tgtattaaat actcctaaaa
    59341 gcatgacaaa cgtctgctct atcattatag gaattgctaa ctttataaca tttttcctta
    59401 taaacatccc tattcctctt ttccctcttt atataaattt aatttttaat tagtttatcg
    59461 aactgtaaat tgacaatgca aagtttagaa ttgtattgtt cgcattataa tatactgctt
    59521 tcaaataata taaatcttgt ttaatatcat ttgaacacag tatatcttta taattatctt
    59581 atgtttatta ttttttatgg ataccacatt taaaatattt attaatttaa tataaatatt
    59641 ttccgttatt attaaaagta gctatatttc gttaatattg tatcactatc gtgtagcaat
    59701 aacaataagt acattttata tattttttat aatattattt aatcatccaa acttttacca
    59761 ctttttcaat atataaaata ttacacttta gatgtaacaa aatcgcatcc atttaaatat
    59821 tgtattttat agactaattt taggatgtga tactttggtt aatttaaatg caaataatct
    59881 aaatgtaaat atggtttatc ctatttcttc cacagcaccc atacgtttca gaagatatac
    59941 tgtttcatat ttagaaaaca tggaaaatat ttatttaact atagcaacat actttgatac
    60001 acttggttta ggcacaatga atattgacaa agtttatggt caatgggctt ggtttactga
    60061 taatatatat gatttaaatc tatttgtttt tgtaggaaat tatccttatc aaattgctaa
    60121 aaacagatat gatacatttg tagatatttt gccagtagct attacttcta ttgtcaatgg
    60181 agatagagta tttttaattt caaatccttg tttgttaaat tcaaaaatta cagttagatt
    60241 tatatctagt catcctactc ttaatagaac agttgattat ggcaatatta gagattttat
    60301 tttttaaaac tgcaacatga tgtgctatta aaaaataccc taaatttaat gatattatta
    60361 aataactaga atatttttaa ttggcacatc atgcctagct attataaatt cataatatta
    60421 ttttacttaa gataagtact gtattttatc tatttgtata tttttattta cctagtttct
    60481 cagttctata tcctatttct ttattagcta gcttataacc ttcttgtatc atttcttctc
    60541 tcgttaatgc actccctaat aaattgtcaa tactcagttg ctttctatca ctaaaatact
    60601 tatccaataa tgattcctct atatcttcct gatatgccaa atttccttca tgcattatat
    60661 attttacatc aaaaccttct ttatttaata cttttcccac caagatactt ctatgacatc
    60721 ttataggttc ttgcatagct cctaataaaa ctatcctata acccatttga caaccctttt
    60781 ttaatctttc tattccgttt aaaaaaatat cttcttttgc tactttctca aaatctgcat
    60841 aaccttcttg cgtatataca tctttattag ttcttttagc tccaaattct tttcccatgt
    60901 atatatataa aaatccggaa tttctaagag attcgttaaa tgcctcttta ttgtattgaa
    60961 tattatattt agaatatgga gtttctctaa tgtcaactac acaatttatg tcatattttt
    61021 ttatcatatt aataagctta tcatatggat aatttgaatg tcctattgcg aatatttcca
    61081 tataaacacc ctcctattct ttgaaattag tatctatata tgtagatacc cgatttactt
    61141 aaaattaaat aaagtattac tttaaatacc caatatcttt ttttcttgat attgtatatt
    61201 tttttacttt atatccttaa aaaaatatac aa
//
LOCUS       DAEHWO010000013        58767 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEHWO010000013 DAEHWO010000000
VERSION     DAEHWO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58767
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.013"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            130..480
                     /locus_tag="KNP54_001064"
     CDS             130..480
                     /locus_tag="KNP54_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBF0891983.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            499..2142
                     /locus_tag="KNP54_001065"
     CDS             499..2142
                     /locus_tag="KNP54_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBF0891984.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2223..4280
                     /gene="recG"
                     /locus_tag="KNP54_001066"
     CDS             2223..4280
                     /gene="recG"
                     /locus_tag="KNP54_001066"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBF0891985.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4339..4893
                     /gene="rsmD"
                     /locus_tag="KNP54_001067"
     CDS             4339..4893
                     /gene="rsmD"
                     /locus_tag="KNP54_001067"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBF0891986.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4895..5392
                     /gene="coaD"
                     /locus_tag="KNP54_001068"
     CDS             4895..5392
                     /gene="coaD"
                     /locus_tag="KNP54_001068"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBF0891987.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5396..5920
                     /locus_tag="KNP54_001069"
     CDS             5396..5920
                     /locus_tag="KNP54_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891988.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6264..8183
                     /locus_tag="KNP54_001070"
     CDS             6264..8183
                     /locus_tag="KNP54_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0891989.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENIL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8196..8483
                     /locus_tag="KNP54_001071"
     CDS             8196..8483
                     /locus_tag="KNP54_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0891990.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8616..9875
                     /locus_tag="KNP54_001072"
     CDS             8616..9875
                     /locus_tag="KNP54_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBF0891991.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLMGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            9878..10618
                     /locus_tag="KNP54_001073"
     CDS             9878..10618
                     /locus_tag="KNP54_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBF0891992.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10941..12251
                     /locus_tag="KNP54_001074"
     CDS             10941..12251
                     /locus_tag="KNP54_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBF0891993.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLISS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12349..13266
                     /locus_tag="KNP54_001075"
     CDS             12349..13266
                     /locus_tag="KNP54_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBF0891994.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            13282..14091
                     /locus_tag="KNP54_001076"
     CDS             13282..14091
                     /locus_tag="KNP54_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBF0891995.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14149..15897
                     /locus_tag="KNP54_001077"
     CDS             14149..15897
                     /locus_tag="KNP54_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBF0891996.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYIGIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKVREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     RYDKVKKYVLELLDRV"
     gene            16159..17181
                     /locus_tag="KNP54_001078"
     CDS             16159..17181
                     /locus_tag="KNP54_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBF0891997.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLSSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEVSRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            17186..19492
                     /locus_tag="KNP54_001079"
     CDS             17186..19492
                     /locus_tag="KNP54_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBF0891998.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTTS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            19464..20579
                     /locus_tag="KNP54_001080"
     CDS             19464..20579
                     /locus_tag="KNP54_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0891999.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLNSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20597..22015
                     /locus_tag="KNP54_001081"
     CDS             20597..22015
                     /locus_tag="KNP54_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBF0892000.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            22030..23238
                     /locus_tag="KNP54_001082"
     CDS             22030..23238
                     /locus_tag="KNP54_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892001.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(23312..24700)
                     /locus_tag="KNP54_001083"
     CDS             complement(23312..24700)
                     /locus_tag="KNP54_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBF0892002.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IGFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            25041..26375
                     /locus_tag="KNP54_001084"
     CDS             25041..26375
                     /locus_tag="KNP54_001084"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBF0892003.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREISYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26517..27434)
                     /locus_tag="KNP54_001085"
     CDS             complement(26517..27434)
                     /locus_tag="KNP54_001085"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBF0892004.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27642..28526
                     /locus_tag="KNP54_001086"
     CDS             27642..28526
                     /locus_tag="KNP54_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBF0892005.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEEKKVVEGSKKTQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            28739..30580
                     /locus_tag="KNP54_001087"
     CDS             28739..30580
                     /locus_tag="KNP54_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HBF0892006.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVED
                     IKIENKSARLIGKEEALKYKLDSVVSKKVDKIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSSRESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            30885..31592
                     /locus_tag="KNP54_001088"
     CDS             30885..31592
                     /locus_tag="KNP54_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892007.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            31586..32896
                     /locus_tag="KNP54_001089"
     CDS             31586..32896
                     /locus_tag="KNP54_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0892008.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNVAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKSEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            33013..33696
                     /locus_tag="KNP54_001090"
     CDS             33013..33696
                     /locus_tag="KNP54_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892009.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDEPFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            33689..36076
                     /locus_tag="KNP54_001091"
     CDS             33689..36076
                     /locus_tag="KNP54_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0892010.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGKMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKLNDKSNLSI
                     EQAKSKLNKIANDVGLDTINVAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQVKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            36356..37498
                     /locus_tag="KNP54_001092"
     CDS             36356..37498
                     /locus_tag="KNP54_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBF0892011.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            37517..38041
                     /locus_tag="KNP54_001093"
     CDS             37517..38041
                     /locus_tag="KNP54_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBF0892012.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            38141..38959
                     /locus_tag="KNP54_001094"
     CDS             38141..38959
                     /locus_tag="KNP54_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0892013.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYIASNIHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLNPTKAIEKVVLCLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFSGENKTIKENIKYSYL"
     gene            39037..39348
                     /locus_tag="KNP54_001095"
     CDS             39037..39348
                     /locus_tag="KNP54_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBF0892014.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSVSSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(39525..40208)
                     /locus_tag="KNP54_001096"
     CDS             complement(39525..40208)
                     /locus_tag="KNP54_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892015.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(40301..40942)
                     /locus_tag="KNP54_001097"
     CDS             complement(40301..40942)
                     /locus_tag="KNP54_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0892016.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHTYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(41116..43119)
                     /locus_tag="KNP54_001098"
     CDS             complement(41116..43119)
                     /locus_tag="KNP54_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBF0892017.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELMKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(43272..43910)
                     /gene="recX"
                     /locus_tag="KNP54_001099"
     CDS             complement(43272..43910)
                     /gene="recX"
                     /locus_tag="KNP54_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBF0892018.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            44186..44875
                     /locus_tag="KNP54_001100"
     CDS             44186..44875
                     /locus_tag="KNP54_001100"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBF0892019.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            44876..45448
                     /gene="yqeK"
                     /locus_tag="KNP54_001101"
     CDS             44876..45448
                     /gene="yqeK"
                     /locus_tag="KNP54_001101"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBF0892020.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            45565..45915
                     /gene="rsfS"
                     /locus_tag="KNP54_001102"
     CDS             45565..45915
                     /gene="rsfS"
                     /locus_tag="KNP54_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBF0892021.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            46269..48689
                     /locus_tag="KNP54_001103"
     CDS             46269..48689
                     /locus_tag="KNP54_001103"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBF0892022.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDILDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            49542..50210
                     /locus_tag="KNP54_001104"
     CDS             49542..50210
                     /locus_tag="KNP54_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBF0892023.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            50250..50330
                     /locus_tag="KNP54_001105"
                     /pseudo
     CDS             50250..50330
                     /locus_tag="KNP54_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(50693..51810)
                     /locus_tag="KNP54_001106"
                     /pseudo
     CDS             complement(50693..51810)
                     /locus_tag="KNP54_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861579.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            52026..53396
                     /locus_tag="KNP54_001107"
     CDS             52026..53396
                     /locus_tag="KNP54_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBF0892024.1"
                     /translation="MKLKKLLSLGLVSMFVAGFPISANALDKIDKIQGADKYETAGII
                     ADKQSYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETFLKDKGIETRRLQGNDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGIESYAIGGTSSMSDSLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            53690..53848
                     /locus_tag="KNP54_001108"
     CDS             53690..53848
                     /locus_tag="KNP54_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892025.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   54134..54692
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=54134..54163
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaatt"
     regulatory      complement(54833..54930)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            55157..55540
                     /locus_tag="KNP54_001109"
                     /pseudo
     CDS             55157..55540
                     /locus_tag="KNP54_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(55718..56713)
                     /locus_tag="KNP54_001110"
     CDS             complement(55718..56713)
                     /locus_tag="KNP54_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBF0892026.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(56834..58462)
                     /gene="aspD"
                     /locus_tag="KNP54_001111"
     CDS             complement(56834..58462)
                     /gene="aspD"
                     /locus_tag="KNP54_001111"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBF0892027.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        22647 a         6662 c         9948 g        19510 t
ORIGIN      
        1 ttttctaggt ttaaattata ccatatttat agtatgatat gattataatt ttatataata
       61 aataagtaaa aatagtaaaa aataaattaa gaaatgtttt taataaaaat aagcttaagg
      121 gggtcaacca tgagtgcaaa ggtaacgaat caatatggaa atatagaaat agataatcaa
      181 gtaatagctc aagtcgtata tagagctgca atggaaagtt atggcttagt aggtttagca
      241 tataagtcta aaggaatagt agagctatta aaaggcgaga acgcaactaa aggtgtaaga
      301 gttgaggaag tagaagaaga tgccatagca atcgaacttt atgttataat acaatatggt
      361 acaaatatat ctactgttgc caataatata atagatagag taaaatatgt agttgaaaaa
      421 atgactggcg taagagttac tagaattgat attaatgtac aaggaataag agttaagtaa
      481 tttcatagga ggaaacaaat gattcaatat atagatggta aaaggttaag ggagatgttt
      541 atttcaggtg caaacaatct ccaaaacaat aaagagttag ttgacaagtt aaatgtattc
      601 cctgtaccag atggagatac aggaactaat atgtcattaa caatatctta tgccttaaaa
      661 gaattagcaa aagttgaaaa tgataatata tcagatatcg gaaaagcatt atctaaaggt
      721 tctttaatgg gagctagagg aaactcagga gttatacttt cacaaataat cagaggtata
      781 gctaaatcta tagaaggaaa aagtaaatta tcaacagaag atttagcaaa agcttttaaa
      841 aatggttcag acacagcata taaagctgta ataaaaccaa ttgaaggaac tatacttact
      901 gtagttagag aaagtggaga gtttgcaata aaaactgcga aaaaagagaa agatgtagta
      961 aagtttttaa gtatgcttgt gaaggaatca aattcttcat tagaaagaac tccagacctt
     1021 ctaaagaatc taaaagaagc tggtgtggtt gactctggtg gaaagggtct tgtacttata
     1081 tatgaaggaa tgttagcttc tataaaaggc gataacatag aaataaaaaa tgttgaccta
     1141 gatactaata tttcaacaag tatggatttt gcaaagagta ctactagcac agatgatata
     1201 aaatattgct attgtacaga atttatttta gaaagttcta aggtagaaga tactaaaata
     1261 agagacataa tgatggctta tggtgatagc ctagcagtag ttggagatga tggagtcata
     1321 aaggtacatg tacacactaa tgacccagga aatgtacttc aagaagctct aaagtacggt
     1381 caattattaa ctataaaaat agaaaatatg aagttacaac atgaaaatac attactggat
     1441 gtagaagaaa agaaagaaaa tgatagtgaa cctttagaag aagaaaaaga gtttgggttt
     1501 atagctactt ctatgggtga aggtttggca aatatattta aagatttcgg agttgaccat
     1561 ataatagaag gtggtcaaac tatgaatcca agtactgaag attttatgaa tgctataaag
     1621 catataaatg ctaaaaatat atttattttc ccaaataaca gcaatataat aatggctgct
     1681 aatcaggcaa aagaattgag tgataaaaat ataatagtta tacctacaaa aaatacgcct
     1741 caaggatttg ctgcattagt aacttttaat ggagaattaa gcgaagatga aaataaagaa
     1801 gctatgatga atgctttaaa ctcagttaaa tcaggtcaag taacttttgc tgttagggat
     1861 acagtgatga atgaaattga tgttaaagaa ggtaatataa ttggaattgc agaaggaaat
     1921 ttattatcag caggagatta tgtggatgaa gtaacatcaa accttattga aaagttggtt
     1981 gatgaagata ctgctataat aacattattc tttggtgaag atgttacaga atctcaagca
     2041 aatgaactac gtacttcttt agaagaaaag tttgaagatg tagatgtaga gttatattat
     2101 ggaggacaac ctctttatta ttacttaatt tcagttgaat aatgattata agaacctgta
     2161 tgaccaagta gcttttataa aattggttgt acaggatttt tgtgtagtag gtgatatatt
     2221 tgttggattt atataaagat gttcaatatg ttaagggaat aggacctaaa aaagcagata
     2281 aattaaataa actgggtata tttacactaa aagacctatt gtattatttt ccaagacaat
     2341 ttgaagatag aaataatcta aagaaaatag cacaattaga agatggtgag aaagttacga
     2401 taaaagcagt aatatcaagt ataaatacat ttagcccaaa agaaggtatg actttaacaa
     2461 agattgatgt aaaagatgag acaggctcgg ctaaattagt gttttttaat aagagttata
     2521 taaaaaatac ttttcgtcca ggagattcaa tattagtttt tgggaaggtt aagaaaaaat
     2581 ttaataactt agaacttaca tcatgtgaat tagaatatct tactaattca cctaagaata
     2641 catgtagatt tatgcctgtg taccagctta catacggtgt tacaaataaa gaaattatga
     2701 gtataattag aacagtactt gaagataaag aattaattat acaagaatat atgccacaaa
     2761 gaattataga aaaatatagg ctatgtagta tagattttgc agttagaaac atacattcac
     2821 caagtagtaa ggaatcatta aaaatagctt tatatagaat tgtatttgaa gaattactta
     2881 tactacaact agggttgttt gtatttaaaa gtggcagaaa taaagaagat ggaataaagt
     2941 ttgaaacaag taaagactta aaaaaaataa taagtgcttt accatttaaa ctgactaaag
     3001 ctcaaaacag ggcattagat gaaattatac aagatatgaa tttagagaaa ataatgaata
     3061 gattggtaca aggtgatgta gggagtggta aaacagtagt agctctctta gcacttgcaa
     3121 attgtgtttt aaatggttat cagggcgctt tgatggcacc tacagagata ttagcagggc
     3181 aacattatat ttcacttact gagtctctaa aagattttgg aataaatgta ggtctattaa
     3241 taggtagtct tacaaaaaaa caaaaggata cagtattgga acaaataaag aataatgaga
     3301 ttgatatatt aataggtaca catgcactaa ttgaagataa ggttgaattt aataatattg
     3361 gtttagttat aacagatgaa caacatagat ttggtgttat gcaaaggagc aaactttcat
     3421 tgaaaggagc aaatcctgat atattagtaa tgacagcaac accaatacca agaactttag
     3481 cacttatact ctatggagat ttagatattt ctattataga tgaacttcct ccaggaagac
     3541 agccaataga aacaattgct attgaaaaaa gtaagcgaga tagagcatat aataatcttg
     3601 taagaagaga ggttgaatca ggaagacaag tgtacattgt atgtcccttg gtagaagaaa
     3661 gtgaagccat agaagccaaa tcagcagttg aacttgttga ggagttaaga gcggaatatt
     3721 ttcacgactt aaggcttggg ttgcttcatg gtaaaatgaa gtcaagtgaa aaagatgaag
     3781 taatgagact ttttaaagat aaagaaatag atattttagt ttcaacaaca gtaatagaag
     3841 ttggtgtcaa tgtgccaaat gcaacattaa tgataataga aaatgcagaa agatttggac
     3901 ttgcacaatt acatcagctt agagggcgag ttggaagagg tagtcataaa tcgtattgtg
     3961 tactaattta tgattctaaa acagatgtat gtagacaaag aatggctata atggaagaga
     4021 ccaatgatgg ttttaagatt tcagagaagg atttagaaat aagaggacct ggggaatttt
     4081 ttgggacaag gcagcatggt cttccagaac ttaaggtagc aaacttattt aagcatataa
     4141 aaatactgaa gttagcacag caagaagctc gatatatatt gggtgaagat aataatctac
     4201 aattaaaaga aaacatggca ctcaaaaaag aaattataga taaatttaaa gatacattga
     4261 aagaaatttc attaaattaa ttttaaattg tgttaaaata ttactaatgt aataatgtgc
     4321 tgaagggaga ttgtcatatt gagagtaatt tcaggaaaag cgagaggatt aaaactaaat
     4381 actccaaaaa atgaagatgt aaggccaact acagatagag taaaagagtc tctatttaat
     4441 atgataaatt catatataat ggaaagtgaa gttctggatt tatttgctgg gactggttct
     4501 ttaggaatag agtgcttatc taggggtgcc aagtcatgta cttttgtaga tattagtaag
     4561 gaaagcatag atattgttaa gtccaatata aaaaaggcaa gagttgaaag tgaaagtatt
     4621 attttaaacc ttgattttaa gactgcaata gataaactta aattacaaaa tagtaaattt
     4681 gacataattt ttatggaccc tccgtattat aaaaatatgt ttatagaagc tattgaaaaa
     4741 attgataatt ctaatctatt gaacgaagat ggaataatag ttgtagaaca tgatacgaat
     4801 gatttatttc cagataagat atgtaaattg gagaaaacta gagataagaa atatggaaat
     4861 actacattaa ctttttataa gatggaggca taatatggaa aataaaccta gaaaagctat
     4921 atttgcagga agttttgacc caattactaa tggacattta gatattattt gcagggcttc
     4981 gaagttattt gacgaattac aaataggagt attaaataat cctaataaaa agggtctatt
     5041 tagctttgat gaaagagtaa aacttataga aaaaagtaca agccatttaa ataatataaa
     5101 agttgtgact tttgatggtt tattaataaa ttactgtcag gaaaatggga ttggagcatt
     5161 agttagaggt gtgagaagtg gtgctgatgt tgattatgaa cttcagatgg cacatatgaa
     5221 tagagagctt aatccagata tagagactat aattttacca agttgtacaa aatattcatt
     5281 tataagttca tctttaataa aagaggtttt gctctttgat gctgatataa aaaatttggt
     5341 tccaaagatt gttttggaag aattaaagaa aaaaactagt gggggtaatt gatatatgaa
     5401 gatagattta gaaatgattg aactatttga gcagttagag gagatattta gaagtgcttc
     5461 tacaatccct ttctcacata aatgcacagt ggataaagat gaggttttag caataattaa
     5521 tgatataaga actttaatac cagaagaagt aacacaggca gtatggatta ataaagaaag
     5581 aaataaaata ataagtcaag ctaagcaaga tgctacaaat atagttgaac aagcgaaaaa
     5641 agaagctgag agaatacaac aagaatatca agataatata gaggaattaa agaaaaattc
     5701 tgaagatgta gtaaaggcat atgtagaatc cagtgaacct gttgttcaag cagaccaaag
     5761 agcaaaagat atagttgata gagctgagag aatagccaat gagataagaa ttgggtcaat
     5821 tgaatatgca gaggatgtgc tttctagtgt tgagtataat ttaagagaaa tattagaaga
     5881 agtaaaaaga gataaagctg aacttagacc taaaaaataa attttaaata aataaaaatg
     5941 gagctatcac acaaaaaatt ccaatttatg tgtgatagct ctcttttaat atagcaattt
     6001 tttgttatat aattgtgctt tttagattac ttatatctta ttttgatatt ataatgtagt
     6061 ttaatctttt atttgttgaa atcaacttat ttatttgtat aaataatata ggttattttc
     6121 aaattttttt aataatttta ccactgtctt cttttagatt agagttagac tgtgcaaaat
     6181 tataaaataa tactaaatca tgtgcaatta tttggtatgg cactacatgt agaaaatata
     6241 gataataaaa ttaaggaggt agtatgaagg aaagggctaa aaaaatatta gattttatta
     6301 ttaaaaataa caatgtaaca tcacaagaac tacaagaaaa gtttaatgtt tcaaagagaa
     6361 ctatttatta cgatattcta gctataaatg aacaactagg aaaaagtggt aatataaaaa
     6421 atgtaaaaca caaatttata tttgaaggta atttatgtga tgcaaggaaa ataatttcaa
     6481 ctgaagaaga taaattttta gatagtgatt acagaaaaac ttttatatta aacaagatat
     6541 tacttggcga aaaaatatca atagaaaaac taacaaatga aatgttactt tcaaaaaaca
     6601 cagtagtaca aacaataact gatgtaaaaa aataccttca aacaatgggg ttaagattag
     6661 agtataaggg aaagtacaaa attataggtg atgaatacgt tattagagag ctgtttctga
     6721 taattgttca agaaaatata ttggaaatta attctataag tgaggaagta agtagtttcg
     6781 atacaaaagg acatataaaa cttactgatt attctttatt aaatctaact aagtttgtgg
     6841 aatttctaaa taaaaggata agagatggga aaacattata ctcatataaa tatctaaatg
     6901 aagctaaaaa aattagttac tttagtaatt gtaaagaact tttatgtgaa gaagctaatg
     6961 aaaatgaaca agcctatata tgcacttaca taagttcact tcccagctta aatagtgaag
     7021 ttaaggaaga tgttgttgaa gaatatgtag ataaacttat agataagttt gaagtaaata
     7081 cagcaataaa attagaaagt aagcatgagt ttaagaaaaa tattttaagg cacctccatt
     7141 cttcttacaa cagaatacga tttaagtttc ctattagaaa tccaatgtta gatgagacta
     7201 agtataaaca tgagtcactt tataaaatta taaaatcaat tatagaaaat gaagaagagt
     7261 ttcctgtatt tgaggggata agagaagaag aaataggatt tatagcagcg tattttggag
     7321 gatatttaag agggtctagg gataatggtc taagaagaaa taaagtctta ctagtttgtc
     7381 ctaatggtct tatggtatca aagagtttgg aaatacaact atataaatac ataccaacca
     7441 tagaaatagt aggtatagta tccattaagc aactaaaaga agtaaatgta tactacgatt
     7501 acataattac aactatagat atacaaaatg taaacaacgt aattgttgta aatcctcttt
     7561 taacatcatc agatgttcaa ttacttatga acaaactaat aagtgtaaaa gaaaacgaga
     7621 agtatttcaa tcttgaatta ataatacaag ctataagaaa aaatggagtt atcaataatg
     7681 aagaagcact aaaagctgat ttattaaaca taatacacaa gatagatgaa ggagagatgt
     7741 atcaaccaat gttaaaggaa ttaattaatg cagaaagggt caatataata aaaagtgtta
     7801 gagattggaa agaagcaata aaaatagcct caaagccatt gttagaagat aactctatag
     7861 aagagttata tatagaaaat atgataaagt cagttgagaa atatggacca tatattgttt
     7921 tagctgatag atttgctcta ccacatgcaa gttctaaaga aggagtaaac aagcttgcta
     7981 tgtctttact aatagtagaa gatgaagttg atttattagg aaaaccagta aatatattta
     8041 tggtattagc tgctgtagat aacactactc acattagagc attagcatca ctatcagaga
     8101 tgatgtacga ggaagaaaat gtaaaactaa taattaatgg tgataaaagt tcaatactag
     8161 aacttataaa taagcaaaat taggaggaat gaaaaatgaa gatattagca gtatgtggtt
     8221 ttggtgtagg ttcatcaatg gtattaaaaa tgacaataca aaaggctcta aagcagttag
     8281 gtatagaatg tgaagtagaa aatacagata taaattcagc tagaggtgct gattgtgact
     8341 gtatattcac aagtcaagaa ttgttaaatg aattaaaagg aacttgtaat gtagatgtat
     8401 atccagttaa aaagtacatg gatttagcag aagtcacaga agttgttcaa acttttttaa
     8461 gtgataaaaa tgataagaaa tagtataagt tttaaaaagt aaatttaagt taatcagaat
     8521 aaaataaaaa cttactaaat tcaaaaatag taagaaagag aggagggatt tagtggtaga
     8581 aaacttaaac agttgaccta tcactaaaaa atataatgct tgattttatt tcaaataata
     8641 ttttacgtaa tccatctatg ttaattggat taatagcagc atttggtctt gtactacaga
     8701 agaagaaagc atctgatgtt ataaaggggt cactacttgc agctttcgga attataatta
     8761 tggagactgg aacaggtatg ttagttagtt caatagcacc aattaatgga gctttccaaa
     8821 gtataagtgg tggtgcagta acaaaaggtt taagtgatgt tacttttact gcaagttatg
     8881 gtggaattat aggtttagca atgtttgcgg gtttagctat tcacctaatg atagcaagat
     8941 ttactcctat taagacaatc tttttaacag gtcacatgct ttattggttc ccattcatat
     9001 ttgtagcttc aggagttgaa gctggattaa atggtggagt attaatagct tttgcagcag
     9061 tattatcagc actctattgg tcaataatgc cttggttatt aagaaaatat gtgtttgatg
     9121 ttataggaga tgattctttt acattaggtc atccatctgg ttgtttagca cttatatcag
     9181 gatttgttgc taaattagta ggaaataaag aaaaatctac agaagatata aacatacctc
     9241 aaagtttatc attttttaga gaaatatcta taagtggtgg aatggcagtg tttttaatgt
     9301 ttatagttgt tgggatagta ataccaggtg cgtttaaaga tagtaatgag tttattggaa
     9361 cgtatgcaat aaagcaaggt ctttcttttg gagcaggtct tataataatg cttcatgggg
     9421 taagaatgct aataaatcaa ataatgccag catttcaagg tatatctgaa aaagttgtgc
     9481 caaatgcact acctgctttt gactgtccaa tattatttaa ttataaacca aatgctgtat
     9541 taatgggatt cttagttgct atgctaacat ctacagctat gattttaata tgtaactact
     9601 ttaatgtatt taatttgcta cttataccac ttgttataac ttcattcttt gagtgtggag
     9661 cagcagcagt aataggagaa tcacaaggtg gtatacgtgg agctataata ggtacagcta
     9721 tagctgcaat atttatggta gttttagtag gaatatctgc tgtaatttac tcaggaacta
     9781 ttcaaaattg gatactaata tttggaggta atgacctttc attatttggt ataatcagta
     9841 ggtttatagg ttcactattt ggaggaatat tatagatatg aaatttaaat acatagatga
     9901 gataagaaga ttaattgata taatagaaaa cgaagaaaaa gtcaatatgg aaaaagcagt
     9961 acaaatcttt gttgaagcaa tagaaagtaa aaatgctata ttttcatttg gagcttcaca
    10021 tgcaggaata ttaacagaag aattattcta tagagcaggt ggctgtgttc ttataaatcc
    10081 agtatttgca aaatctctaa tgttagatac agcgcctata actcacacaa gtaagatgga
    10141 aagattagaa ggatatggta cagctctagc tgataaaact ccaattaaaa aaggagatgt
    10201 agttatagtt cattcagtat ctggtagaaa tccagtaagt atagagtttg ctatgaaagc
    10261 taaggaaaat aaggcaatag taatatgtat aactaattta agttactcaa aaagtgtatc
    10321 ttcaagacat tcttcaggaa aaaaacttta tgaagtatgc gatttagtga tagataatca
    10381 tggtcaaaag ggagatgcct gtgtagagat agatggatta aaccaaaaag ttagtccaac
    10441 ttctactgta atagcaacta ctgtgatgaa ctctattata gctcaagcta ctcaggaatt
    10501 agttaataaa gggctaaaga atcctccgat tttctatagt gcaaatattg atggtggaga
    10561 tgagttaaat aagaagattt ttgatgaata taaaagtgta attcattatg aatattaagg
    10621 ttaaaaaaat atgttaatga actttgaagt ttatcaacaa agaatattaa taatatataa
    10681 taaatgctat catttaaaag ctgtaggtaa aaatctacag ctttttatta ttgtagatta
    10741 aaaagatgcg taattaaatt ttaaattgga gaaaataaat tggaaggtat caattataaa
    10801 tattagaaac gttgtcatag aaaaaaacta tattaaaaaa aagtacatag aaaaaactga
    10861 ttagacaata aatacatgct ttgataatat tttaaatgga gtgaaaatgt gtagaattat
    10921 aatgaaaaaa gaaaataaaa atgaaaaaag aaaataaaat ggagggaata aaagtgggta
    10981 tgttaaaaaa attatgttca ctagctatgg tagcaattat gactacaaca cttataacag
    11041 ggtgttcaag tggaaatgga aaagattcaa aaaaggatgg cgaaaaagaa aaactagttc
    11101 tttggatgcc accagtagaa aataatatga aggaagtttg ggaccctatt ttagataaat
    11161 ttgaggaaaa aaataactgt gaagtagatt tacagataat tccttgggat aattattctg
    11221 aaaaatttgc aacagctata agtgctggcg aaggtccaga tgtaggatat atgtatgcag
    11281 aaatgtatcc acagtttata gaaagtggag cagtagaaga tttgactaac tatgcaacta
    11341 aagaggataa agagcaatct atttatataa aaacatctga aatgatgggt ggaatgtatg
    11401 gtatgccatt ccaagcagca aatccagggg tattatacta taacaaggat attttagaga
    11461 aactaggaga aaaacctcct aaaacatggg aagattttaa aagaatttgt aaaaaagcaa
    11521 cgcaagatac tgatggtgat ggaaagatag accaatgggg attagctcag ggatggggag
    11581 ctaaaacttt tggtaactta aactggaact ggtatcctta tttatggcaa gctggtggag
    11641 atatatttaa tgatgattta aaatcggtta aatttaatga taagagtggt ttagaagcag
    11701 ctaagttctt aaaagaatta caagcatatg tgcctgaaga ttctttatct aaagatagta
    11761 atgaaatgat agaaagtgta tttggaccag ggaaagcagc atttacaata atgttatctt
    11821 ctgctgcaac aagtgtattt gatgaatcat tcccggattt aaattgggga tttgtaactg
    11881 gactagaaga taagaaagca gcaacttttg gagcagtaga ccatttatct ttaatctcat
    11941 ctgcgaaaaa taaagaactt gcatacaagt taatacaaca tatgttaagt gttgaatcaa
    12001 tgacagaatt tcataaagca ataccaagag caccaataac aaaaggtgaa ccatatcaag
    12061 gtgatgaaag attcaaagaa atggtggaaa atgacaaaaa tgtatataga ccattagtag
    12121 taggacctca tggagttgaa atatatgaat atttatggaa agaacttcaa actatgattt
    12181 caggagataa aactccaaaa caagcgttag atgatgctgc aaaatattca aatgatttat
    12241 tagcacaata aaagtttaaa gctgtaatat gttgtaaagt actttacaga ttaaaattag
    12301 cattgtattt ataaatacaa tgctaatatt tatattggag aggataaaat ggaaaactta
    12361 gttagagagt ttgaagaaaa ttcaaaaaga aaaaaaacaa aattaaatat taaaccatat
    12421 atgtatatat tgccattggg aataatttta gtggcgtttt atgtgatacc aataataatg
    12481 tcaatatact ttagttttac aaagtataat attattagtc cagctacttt tataggttta
    12541 gaaaattata aaaaattatt tacagatgaa acattaaaag tatctattat aaatactatt
    12601 aaatttactg ttgttgtagt accttgccaa actatattat cattgatttt ggctgtttgg
    12661 attacaggaa aaggaaatag taaaatagct tcatttgcta aaggtgctat atttatacca
    12721 gtattatcat ctatggtttt gataggtatg gtatggaggg ctttattgaa tggagaaggt
    12781 tctattatat atcaggtatt aggtgccttt ggaatagaat catctaaact tttaggagat
    12841 agtaagacag cattacctac acttatgttt atatctatgt ggaaaaatat agggtatttc
    12901 atggtaattt atatttcagc tataatgaat ttaccaaaac actgctatga agtagcgaag
    12961 gttgatgggg ctacaaaact tcaagaattt ataaaaataa ctgtaccttt attgaaacca
    13021 actacaataa tggttgtatt tttagggtcg atatggtcat tacaagtatt tgacttaatt
    13081 tatactgtga caggtggagg tccaggtata tctactatga gtatagttat gcatgcattt
    13141 aacttaaact ttaaaaactt taattctgga tatgcaatga ctgtagcaaa cgtattattt
    13201 ttgttaatag cagtagtttc gattttacaa aataagcttg taaaacgaga caattcagat
    13261 ttttagaaag gtaggtataa tatgaaaaca gcaagaagat tattaagtga tggtttactt
    13321 ttatttatag cgtgtgcaag tttggtacct tttatataca tgttgataat atcattgaag
    13381 ataacatata actcatatag tttggatata tctttttcaa cagtaaccct tcaaaactat
    13441 atagatattt ttactaaaaa aggatttgca caatattttt ttaatacagc aatagtatct
    13501 ttttcaggtg tattattaaa tttagtattt agtacattag caggatattc ttttgcgaag
    13561 atggatttta aaggtagtga taagttattt ttatttatga taatgacttt aattatacct
    13621 tcccaagtta caatgatacc actatatata ataatgaaac acttaggatg gataaatagt
    13681 tatcttgcac ttattatgcc aataccaact gcatttggcg tatttataat gagacaagct
    13741 attttaggag taccaaaaga gttattagaa tcagcaaaga tagatggttg ttcggatttt
    13801 agaattttaa tacaaatagt gttgccttta attaaaccag cattaattac actagcaata
    13861 tttactttta tgggagcatg gaacgagttt atgtggcctc ttatagctac aactaaagat
    13921 gcaatgagaa cattaacagt tggattatct actcttaaga cattccagat aactaattat
    13981 ggacagatga tggcaggggc tacaataaca tttttacctc catttatttt ctatttgatt
    14041 ttacagagta aatttgttga aggtgtgtct ttgtctggta taaaaggtta aatagtctaa
    14101 tttaataata tataaagaaa cttatataaa tatggaggaa tttaaactat ggaaatttca
    14161 tatgtactga aagattgcac attcaaacac aataaatact cagttgtaga agctgaaact
    14221 tggaaagata aggatttgga tattgtagta gctaaaggtg aaaaatttgc atttcaaatt
    14281 atgttaaaag caacagaaga atttaattgt acaattgata aaagtagtgc tatatcatgg
    14341 aaaggcctgg gaaatagagt aaggttagca ttaaatatgc ctaatagttt agaaaataat
    14401 tttagtataa atatattagg atatgttcaa gatgatacaa aggcatttgt gaatgatgct
    14461 attttaaggg ataaagatgt gttagtagag caatatttgc ctcaaacatt ttggattgaa
    14521 ggtcaagtac cagaagattt tgaagaaaat aaccttgata taggtattga tatatttaaa
    14581 agctttggat atgaagatga agaaaaagtt tgtacaattg atgttcctgt aaaagtaaga
    14641 aatgttgtgc taaagccttt agatgaaagc aagttctttt tagatttatg gcaacatcca
    14701 agctgtttag ctagaatgta taaagttgag ttatggtctg atatacattt tgaaatagtc
    14761 gataactatt taaaagaatt agcatcttta ggagaaaaag ttgcaacagt tatagtttca
    14821 gattatccat gggcagggca aagttgttat aaagtttata aaaatccatc aaacttatat
    14881 gaatataaca tggtaagtgt atcaaaagga ttggatggaa agattaaatg taactttgag
    14941 agtatggata ggtatatagg catagctgat aagtataaaa tggctaagga gatagattta
    15001 tttggtctat taggtaattg gtgtgctggt gagtttggaa atcctgtaga aggttataag
    15061 gaccctataa gagtaagata ttttgatgaa aaggataaag tatttaaatt tataaacaat
    15121 acaaatgatt taaaagaata tataggatta gtattaaatc atttaataga gtgtggatta
    15181 tgggacagag taaggattat agctgatgaa ccaaataatc cagaagtagt caaagagtgt
    15241 atagaattta taaattctac tgtaggtact catcaagtta aatataaatc agcaactcac
    15301 gaccaaaact ttttagacag agctaaagat gaaattgatg atatgtcaat aaatttaaaa
    15361 cttactatac aaaattataa agatatagaa agtcttaaga aaaaaatcaa tgacaagggt
    15421 gggatattga cttggtttgt atgctgtttt ccagaaaaac caaatagttt tttaagttct
    15481 ccttttgtag aaaatagaat aataggatgg tatacttatt actttggtct tgatggattt
    15541 ttaagatggg actataattt atggacagaa gacccttgga aagattcaag ttacaaattc
    15601 cctatttgga aagctggaga tatgttcttt gtttatcctg gaaaagattt aaagccagtt
    15661 agaagtgtca gaatggagaa tttaagattt ggaatacagg attttgagtt atttacaatg
    15721 ttagaaaaag aaaaggtaag agagtatata gaagttgagc ttatgcaaga attattaaat
    15781 aaaaaagaaa atgctgaaat taaaggtttt ggtgacatag aactaggata ttcacttgat
    15841 aattggagat atgataaagt taaaaaatat gtattagagt tgttagacag agtataaaaa
    15901 atataagagt gtctcaaaat gaacttttta gttcatgagg cactcttttt gtatgaaatc
    15961 aatatagttt cattgtttca acaatgaaaa ataggattat ttctattcta agacagccct
    16021 ttagtttttt agttgtattc aatgttttaa aactaactat aaacgctata aagtttataa
    16081 atgacaataa ttatatataa catgatgtac tttaatttgc tataataggg attgaataat
    16141 attatatgga agataacatt gtttgggggg attaatataa aaagaatagg tattattata
    16201 atgttttttt taagtatatc ttttattgga ttttatcttg taataagaga taacagtgat
    16261 acagttaaga tgcaacgagg gataaatata ggtaatgcac tagaatcacc taaggatttt
    16321 ccgtgggatg taaaaatgtc aaataagttt tttgatgata taaaagatgc aggttttgac
    16381 acagtacgta taccagtaag gttttctgat tatacgtcag attctgataa ttttaaaatt
    16441 gatgaagaat tttttaaaaa gattgataaa tatgtagatt atgcattgga taaagactta
    16501 atagttgtgt tggatttaca ccattttgaa gaaattatga aagaaccaag agttcataaa
    16561 gaaaagtttt taaaaatatg gcaacagata gctaataggt atcaaaaata tgataaaaaa
    16621 ttggtatttg aattattaaa tgaacctaaa gaaaatttat cttcacaatt actaaacgaa
    16681 tacattgaag aagcaataaa gataattaga aaaactaacc ccaaaagaac tattatagta
    16741 ggaccatata atttctatca aattgattat ttgaatgaat taaatattcc taaagattct
    16801 aatatagtag tttcttttca ctattacgag ccaaatgatt ttgcatttca aggaaatatc
    16861 tatcataagg gatttgagca cttaagcaat attacttggg aaggaacaaa tgaacaaatg
    16921 gattatttaa aaaaaaggtt tgatactgtg gaaaattggg caaataaaaa taaggtaaaa
    16981 atcttcttgg gtgaatttgg aataacaaaa gaggcaccag aagtttcaag aagagcatgg
    17041 ataaaagctg taagagaaga agctgaaaaa cgaaactttt catgggctta ttgggagctt
    17101 gcatctggat ttggtatata caatcaaatt gaagggactt gggatagaga tatattaagt
    17161 gcattaatag aaaagaggtg attttatgaa gaaaaattca aaaaagatac ttataacttt
    17221 aactattatt actaatgtca tatatatatt gtggagaatt ttttacacag tacctaaaga
    17281 agaagggaag tttgccttaa tatgtgccat aatacttctt tttgtagaga taatgggtat
    17341 gatggaaatg tttgtgcatt attatggtat gtcaaatatt gagtatcctg aaaaaccaat
    17401 cataagtgaa gaactttatc cacatgtaga tgtatttatt gcaacatata atgaatctgt
    17461 tgatttggtt agaaaaactg taaatggatg tattcatatg cagtatccag ataagaaaaa
    17521 ggtacatata tacatatgtg atgatggaaa tcgtgaagaa atgcgtattc tagcagaaaa
    17581 aatgggtgta aattacataa ctagaactga aagagaagga gcaaaagctg gaaatttaaa
    17641 taatgcaatg caacatacaa cttctccttt gattgctaca tttgatgcag atatgatacc
    17701 aatgcatgac tttttaattg ctacagtacc atacttttta aaaaatgagc aagctaaaaa
    17761 agatggagaa aaagaggagt atgaaaaggt tggttttgtg caaactccac agagttttta
    17821 taatccagat ttgttccaat ttaatctgca ctctgaagga aggattccaa atgagcaaga
    17881 ttatttttac agagatattc aattggctag aaataggaca aattctgtaa tttatggtgg
    17941 tagtaataca gttatttcaa gggaagcact tgaagaagtt gatggatttt atacttattc
    18001 tattacagaa gattttgcaa caggtatctt aattcaaagt aaggggtata gatgttatgc
    18061 tattccagaa gtacatgcat caggtttatc tcctacagat ttaaaaagtc ttattaagca
    18121 acgtgaaaga tgggcacgtg gatgtataca aactggtaga cgtctaaata ttttgtttag
    18181 gagaggttta ggtttttggc agaaaataag ttatatttct tcaattactt attggtatgc
    18241 aagtataaaa cgctttgtat atataatggc acctatttta ttttctgtgt ttaatgtgat
    18301 tgtagtaaaa tgtacgttac ttcaagtatt ggtattttgg ttgccaatgt atattttaag
    18361 tagtttatct cttaaaatat tttctcaaaa tataagaaat actagatgga ccaatatata
    18421 tgaaactata atgtttcagt ctttaatgcc agcagtaata cttgaaacgt ttgcaatatc
    18481 taaaaataaa ttttcagtaa caaataagag taaattagaa gaaaatagaa tgtataagtt
    18541 tttacaggga ataccttatt ttatttacat ggtcttatct atcataggaa ttttaaaaat
    18601 gtttgtagca atatttaaaa tgagttcaat gacatattca gttgtattat tttggttgat
    18661 tggaaacctt tttaaccttg ttatggctac attatttata tcagggagac agcagttaag
    18721 aaagtctgag cgttatattg ctgaaattga ttttaagtta aagcaaaatt cttatgttct
    18781 ttcttcaaaa acaattgata tatcagaaaa tgggtttgca tttttgctag aaaatccaga
    18841 atatatttca ccagaagaag agtttgaggt agagtttaga gaaaaatctg gaaatgaaat
    18901 gtatatagcc aatatgaaag caaagattgt taatgttgtg gaagtaaatt caaagtggaa
    18961 atatgcagct tatattacac atattgaaga tagtgaaata gataattgga tgtgtattgt
    19021 tcacgataga atacctactt taccaatgac aatatctaat caactaggtt tctttgatga
    19081 tttgcaaatt aatgtgaaaa aacgtattga aaaaactaga acattatcac gaagaagtcc
    19141 aagaatcaat atgaattttc agatggatat aaaaaataca ggtaaattaa gaatagtgaa
    19201 ttttaattat caatatgtat tattaaattt tgagaataaa agtatttatc ctaaagaaat
    19261 agcattggaa attaatgaaa atattgtgtt agaatgtgat ttgtgtgagg gtaaaattga
    19321 tgaaagaggt atcttatata aagtaaataa cattgacagc ataatgcaaa atttcttttt
    19381 aagagatgaa atgatggatt ggatattaca aaataagaca attcttgttt caaagcctag
    19441 tgaaaagaag gaaaaaagta tagatgagtt tgaacccatg gaatatattt aggagagatg
    19501 aaatgaagac tttaaaagtg tttttttgtt ctacaaaata tcttattttg gtgtttattt
    19561 tttttataaa tactactttt ataagttcag caacaagtga taaaatttta gatttgtcct
    19621 ttaaaaagat agagactgac ttaaattcta agattacata tgaagataca ggtgtaaaaa
    19681 tagaaacgga tagttctaaa agcgataagg aacgttattt atatatttac caaaatataa
    19741 aagaaaattg gagcatgtat aataattttt atattgaaat tcaaaataaa aataaaagtt
    19801 ctcagagaat aaatttaagc atacaaagta aaaatatgct tgaatttaga ttaaaagaag
    19861 gtagtgaagt atttttagaa ggtaaaaata taatatattc agataaaata aaagaaggat
    19921 gcatagaagt accaggtgaa tttgaaggca aaatttatgt gaactttaat agccttataa
    19981 atgaggaaag taatgttgtg ctggactcaa atatgctttc aaacattgtt agttggggaa
    20041 ttacgtttat tccatctgat gaagaacata atattgttat tataaaaaag atatctttat
    20101 tgtctgaaga gaaattaaga tttttaaata atattaaaat aattggcgat gaagaagtac
    20161 aaataccagt attgggtcaa agtataagtc agtatgaagt attaggtctt aaaagtgatt
    20221 ctaaaattaa gtactctctt atgggaaaac aagataatgt aagcatatct caaaaaggta
    20281 aattaacatt aagtaataaa gccaaacctg gacaaattat tttacaagtt aatgttgatg
    20341 ataagtttaa aattggaaag aaaataacat taactgagtc ttggagtgtt aataaaaaag
    20401 ataaggatgg tgttccatat acattagtat atcctgagca atcaccaaca gtacaagata
    20461 tgaaaaaaat aaactttatg aataacatca taacgtttgt tcgaatttta tttgtatctc
    20521 tagtaataat atgctttgga atatatttat attggaaaaa atgttcaaaa actaagtaaa
    20581 gagaggaggt tagattgtgt tattttcaag tttaattttt ttattttatt ttttacctat
    20641 aactttggtt ttatattatg tatttaggtt taaccgaacg atacagaaca tgatattgct
    20701 tgctgttagt ttattttttt atgcttgggg agagccaaaa tttgttgtta tcatgatagt
    20761 ttccataata atgaactata tatttggttt actggtagat agatataggg aaagtaaaat
    20821 aaaagtaaaa gtttttttag ttttgatgtg tgcatacaat ataggtgttt tatttatatt
    20881 taaatatcta gcttttgcgc taagaaatat tagtgaactt attagtactg aattgactat
    20941 acctagtatt gttttaccca taggaatttc attttttaca tttcagggaa tgtcttatgt
    21001 tatagatgta tatcgtagac atggagaagt ccaaaagaac cctttttatg tgggattgta
    21061 tatagcattt ttcccacaat taatagcagg tcctatagtt agatatgaga gtgtggcaga
    21121 acaaattctc aatagaaaag aaacttggaa taaattttct attgggactt gtaggtttat
    21181 aacaggtcta ggtaaaaaag tattaatttc aaataacatg gctatagtag cagactatat
    21241 ttacactatg aatagtcaag gagaaatagc tgcatcactt gcatggcttg gttcaatagc
    21301 ctatactctg caaatattct ttgatttttc tgcttattca gatatggcta taggcttagg
    21361 tcttatgttt ggttttaaat ttgaagagaa ctttaattat ccatatatat caaaatcaat
    21421 tagtgagttt tggagaagat ggcacatttc tttgggaatg tggtttaaga gctatatata
    21481 ctttccgctt ggaggttcta gagtagcaaa taaagatatt atgattagaa atatgtttat
    21541 agtgtggtta tttactggaa tatggcatgg agcagaatgg acatttgtaa tttgggggat
    21601 tttaaacttt gttttcctaa ttatagagcg atttataatg tttgaaaaga ttgaaaatca
    21661 caattttata aaacatattt atgctttatt agtagttaat tttgggtggg tattatttag
    21721 gtcacctaat ttaaaagaag catataatta ttttaaagct atgtttggag gcaatggagc
    21781 tatatggagt gattatacat atatgttttt aaaagaatac tgggttttct ttatatttgc
    21841 atttattttt agtgtaccta ttgcaaagaa aatcaataag tttgttgttg aacaagctaa
    21901 atatagtatg atatttaacg tattttatcc aatctcagct attttattgt tttttatttc
    21961 tgtgacatat ttagtaactg gaagctataa tccatttatt tattttaatt tttagttggg
    22021 aggaaaagta tgaatagatt ttttaaagta agattaataa ctgcaattat gttcttaatt
    22081 attttattcg ctttctctat ctttaatgtt tgttattctg gaaaagatac gatacaggaa
    22141 ataaaaaatt caatagctga aaaaagtagt ttaaaagata caatatcatc tattgataat
    22201 acagtgaatg acaaagtaat atacaaaaat acgttcattg aaacttatgg ctatttacaa
    22261 aaattaatgg gtaaaaatga gttttcaaaa tttagtgttg taaaagatac ttctggaaag
    22321 atgcattata catattttgc taaagctcca aatccagttg gtgtgatagc agatagggta
    22381 agaaaatttt ctgatgaaat ggaaaagcaa aacactaaat tggtttacct aatgactcca
    22441 gataagtata taaaaggagt gacaaaattt ccaaaaggaa taccttattc ttatagtaat
    22501 gagacagcag ataatttttt aaatcaacta aaaaagtata atgtggacta tattgatttt
    22561 agagaaaata ttttaaagag tggtattcca aaagatgatt tattttttaa aacagaccat
    22621 cactggaaag tagaaacttc tttttgggca tttggagaat tagttgagca acttaataaa
    22681 aaatacaata tgaatttaga tgaaaatcat tattatagag ataaggacaa ttataattca
    22741 attgtatatc ctaagtcatt tcttggttct atgggaagaa agactggtat cttatatggt
    22801 ggtatagatg attttacatt aatttatcct aaatttaaga ctaattatac ttattataca
    22861 gattctaaat ctcaaaaatt tgaattaaaa ggaaggtttg aagagagttt aatattatca
    22921 tatcctttta atgcagacct tgatttaatg gatggtcaat cagataagta ttttacatat
    22981 ttattgggga acagaccatt agttaaaata aaaaatatag aaaatccaga tggattaaaa
    23041 gtgctgtttg ttaaagattc tctaattgta ccaacagcag catttttttc ctctgtttgt
    23101 tcatctatag atatgataga ccctagatat tatgatggag atatactaga atatgcaaaa
    23161 tcccatgact atgactttgt ttttatatct gtatatcccc aaaatcttac aaaagaattt
    23221 tttccgtttt gtgagtaaat ttctaaaaaa gttttctgat aaaataaatg gctaactggt
    23281 aaaaagttag ccatttattt tgagtgttat tctaagaaat atttttttta ctaaatactt
    23341 ctttatctat ttttccaagt gattttccta cagtaattga tgataccata gcaccattaa
    23401 catttatcat agtacgtccc atatctagta tagggtctat tgcaagtata ccaccaacta
    23461 atggaaaata agaaccaaga ccaactccag agataacaac tgaaacggcc attgtagcag
    23521 ttcctggaag accagctatt ccaaacgaac taattgttat aacaattaac aacataacat
    23581 aaaagctcat atccatgttt actccagcca tattggcaag tgttacagcc attaaagcag
    23641 gatatatacc tgcacaacca ttcataccca tatttgcacc taaacttgct gtaaagcttg
    23701 atacaccctc atcaactccg tgattttgta ctagactttc tatcgttaca ggcaatgttc
    23761 ctaaactaga acgtgaagta aatgccagaa gtaaagcttc agttgaattt tttatataag
    23821 taatgggatt tagaccattt aaagttataa aaattaaatg tataataaat aatattgcaa
    23881 ctgatatata aagagctaat ataaactgta aaacagatac tattgaacta ataccttgtg
    23941 aagttattgt atttgcaagc agagcaacca cagcataagg cataaattta ataacagtca
    24001 tagacacact tacaattatt ttgtaagatg cttctataaa acctataaat ggttttattg
    24061 tttcaaaatg ttttttactt aatctcttta ttgaggtagc tataaatgta gcaaatatta
    24121 ttgtagctac aatatttcca tttgccatag ccattacagg attagatggt agtaatcctc
    24181 ttaaagtatc cacaagagag tttatttctt taagttcttg attttcaact aaagtaggca
    24241 tattagctcc tacacctaac ttcattatat ttgcaacgat aattccaaca attgcagcta
    24301 tagcagtagt agcaagaagc atacctaaag atttaaatgt cagagttcca agattgttat
    24361 ctttcatatt tataattact tttataatgg ataagaaaac taaaggtact actaacattt
    24421 ttaataagtc cataaatcca gaaccaaata ggctatacca cttacttact tcttgtagcc
    24481 aaatgacttg agttgtatca ttaggaaaac cagcaaaagc ttgtattatg attcccaata
    24541 tgagtcctag tactgtagca tatattgttc tcaatgaaaa ttttattttt ttcttttcaa
    24601 attgtctaac aataaagaac gtacctagaa gtaatattat gaaaaaaatt gttttaaaat
    24661 ctgtaatcat aagaaattgt gataaaaatg aactttccaa tatttttctc cttttattta
    24721 aaaataaatt tttctaagtt taaatgatat caatatatta aaaaaatgtc aatattatat
    24781 cacaatttac ttaaatagag taaaacaagt tgattttgaa aaatgtgatt aagtacagaa
    24841 aaatagggta taataaatgt ttaaagaatt tgaattgtgg taagaaaata aaaaatagct
    24901 tttataagat ttgatttcaa attaaaatgt gttaaataaa taactaaaaa ttattataaa
    24961 aaatgttttc atagaatata tatcaaatga aaagcttaaa ataagtgaag aaattaacta
    25021 gacatcaaag gagagataaa atgagagtaa taataattgg tggtgttgca gctggtatga
    25081 gtgctgcagc aaaattaaaa agaataaaac ctgagtatga agttgttgtt tatgaaaaaa
    25141 ctgaaatagt atcttttggt gcttgtggat taccatactt tgttggtgga ttttttaatg
    25201 atgctgatga attattagca agaacaccag agaaacttag agaagctgga attgatttaa
    25261 atatatttag agaagtcgtt gaggttgata gtgaatctaa gaaaataaaa gtaaaaaaca
    25321 taaaaacaga tgaaatatat gaagattact atgataaatt gatgatagca actggagcaa
    25381 gaagtattat gcctcctata aaaaacataa aattaaagaa tgtttctaca ttaaaaagtt
    25441 tatatgatgg agaatattta aaaaaacttt taagtaatga agataataaa agagtgacaa
    25501 taataggagc tggttttata gggttagaag cagttgaggc atgtaagaaa ttaggtaaag
    25561 atgtagatgt aattcagtta gaagatagaa tattgccaca agtatttgat aaggaaatga
    25621 cggatgtatt agaagaagaa ataaatagac ataatgttaa tttgcactta gatgaaatgg
    25681 ttgtagaact ttgtggagaa gataaagtag aaaaagttat aacaaacaaa ggggaaatag
    25741 atacagatgt agtaataatt gctactggcg tgagacctaa taccgagttt ttgtcaaata
    25801 ctaatataaa aatgctaaaa aatggagcta tagtagttga tgagtatgga agaacttctg
    25861 tagaagatat atactctgct ggagattgtg caactataaa gaatatagta agtaatgaaa
    25921 atgtatatgt tcctttagct actggagcta ataaattggg taggatagta ggagaaaacc
    25981 tagcaggaag agaaatatct tatcaaggtt cactatcttc aagctgtata aaaattatgg
    26041 atatggaggc agcatcaact ggaattacag aaaggcaagc taaagattta ggcataaatg
    26101 tcaaatctaa atttatttct gattataatc aaactcatta ttatccagga agaaataaaa
    26161 tatatgtaaa gcttatttat gatgcagata caaaagttat tttaggcgga caagtggctg
    26221 ggtttaagga tgctgtccaa agagcaaatg tattggcagc tgctatcttt ggaaaaatga
    26281 ccacaaatca acttggaatg ttagatttat gttatgctcc accatttgca agaacatggg
    26341 atgttttaaa tgtagctgga aatgtatcta aataatattt agattatagc taatatagtt
    26401 gacaagcaat taagggaatg aatttaccta aactattttt atcatggtaa aattcattcc
    26461 taaattttta ttccaaattt ttattccaaa tttttagaaa taaggattcc attaaattat
    26521 tcatcaaaat ttaaacgcaa gcttaatcta tcttctccaa gaatagtatt ttcaaaaaca
    26581 ttagtagcat tttctaaata catactaggt atgtctaaag aaggactaaa atgagtcagt
    26641 aaaagttgtt tgacatttcc aagttttgca agattagcag cttctctaaa agtcatatgt
    26701 ttgtttctaa cagcttttga tatatctaaa tcatcaccat acatggcttc acatataaat
    26761 aaatcactat cttttatgaa atctggtatt gattctatag gtcttgtatc ggttgtaaga
    26821 cttatcttaa ctccctttct caattctcct aagaccatat ctggagtgta ttgttttgaa
    26881 tctaaaacta tattttgacc ttcttggagt ttgttccata atattttagg aacttcgttt
    26941 ttagttgcct tatctatatc aaatttaggg tttcttctaa aattaaaact gtatcctaaa
    27001 cactctatag agtgttctaa actgattgtt gaaatttcta aatttcttaa aactttatta
    27061 tctaaagaaa aattgccttg agggttttct ataattttta aagtgtatgg tacatattct
    27121 actaaatttc tcatagaacg tatacaatcg actattccaa ctggaccaac tatagttaaa
    27181 tcacttgtac gaccactatt cccaattgtt gataaaagtc ctaaaagtcc aaatatatgg
    27241 tcaccatgta aatgggttat acaaatcaag tctatatctt taaagccaca tttttttagc
    27301 ttcatagata cctgagtacc ttcaccacag tcaattagta tttttctacc tttatagttt
    27361 ataaatacag aggatagaaa tctgtttggc ataggtacat ttccaccaca tccaagtaaa
    27421 gttaaatcta tcattttttc ccctttctaa aattaacaca aatctgttgt ttgtttttat
    27481 tatgatatcc tattataatt attttaacat taaatataac aataaatgtg tatttgagtc
    27541 aagaaatatt gtcaaataaa gtttttatat agcaatgtat aaaaatttgg aaaacgaaaa
    27601 gtgaaaatta tatttaggag tatttaaagg aggaaaattt aatgaaagta ttaaagaaaa
    27661 ttactatttt gtcattaatt acattaacct tagttggttg tagtaacgga gaagagaaaa
    27721 aagtggttga aggttctaag aaaactcaaa attctaaaaa agatgaacag cctataatag
    27781 tacataaaga tgcaaatata ttgaaagata ggtatgagcc accaaaagga tttaaaagag
    27841 ttgatgtaga aaaaggtagt tttgaatcat ttcttaggaa tactaagcta aaaaattatg
    27901 gagagaaagt aaagtattat gatggaagaa ctaaggaatc aaaaggtatt tatgatagtg
    27961 tatttgatgt tgatattgga aatagagatt tacatcaatg tgcagatgca attatgctta
    28021 tgagagcaga atacttgtat cagaataaac tatatgatga aataagtttt gattttgttg
    28081 atggttttaa ggcgaagtat tcaaaatggg cacaaggata tagaatttca gtaaaagata
    28141 gtggttcaag ctggtataaa gcaactgaat attcaacatc ttatgagagt ttcagaaagt
    28201 ttatggatat agtgtttgca tattcaggaa cgttatctct tgaaaaagaa ttggagcctg
    28261 taaaagttga ggatatgaaa ataggagatg tgtttatagt tggtggaagt ccaggacatg
    28321 caagtataat tatggatatg gcagaaaatg aaaagactgg tgaaaaggta tttatgatag
    28381 cccaaagcta tatgcctgca caacaaacgc aacttcttat taatcgtaaa aatccaaatt
    28441 tgagtccttg gtatagttta gattttgaag gtgatttgac aatacctcaa tggactttta
    28501 aaagagacca gttgaaaaga ttttaaaata ataattttat ataataaaag aaaaatatag
    28561 atgtgaaaaa atgtaattag attaaaacta attggatatg gacaaaatta aattgataga
    28621 taaatattaa aaattacact aattaatctt actatagttt aatatttatc taaaaagttt
    28681 tatgtaaaat ataaatttta tattaaagct aaaactaatt tgaggaggct aatttatatt
    28741 gaagattaga aggtatttaa ttttggtaat tataattcta attacaacaa gtcagagttt
    28801 tatttcttat gggctagagc gatttgaaga aataaccatt tttcacacta atgatataca
    28861 tggaagatat gctgaaggtg atgaccatat acaaatagga aatctagcca cattgaaaaa
    28921 agaaactcca aactcaattt tagtagatgc aggagattgt ttgcatggac ttccaatagt
    28981 aaatatggat agagggaaaa gtgcaattga attaattaaa tgtgctggat atgactatat
    29041 tactcctgga aatcatgact ttaattatgg aaaagataga ctgtttgagt tatctaaaag
    29101 tgctaattta ggagagaata ctttaaaatt tttatcatca aatatttttg aaaatgggaa
    29161 aaaagttttt gatagtaatg atataaaaga aatagatgga ataaaaatag gattttttgg
    29221 actctcaacc caggaaacaa agagcaaaac tggatttaaa aatgtggaag gattagagtt
    29281 taaaaatcct atagaaagtg caacagaaca agtaaatgaa ttaaaaggaa agggtgccaa
    29341 tgtaatagtt gcaatatgtc atattggtac aaatagttta agtaagccaa atagtataga
    29401 tatagcaaat gaggttcaag gaattgattt gattattgat ggacacagcc acactaagtt
    29461 tgaaaatggt aaacaagtgg gtgatacatt gattgtaagt gcaggacaat atttagaaaa
    29521 tattggcgag ataaaactaa ctttggatac taatgatgta gaagatataa aaatagaaaa
    29581 taaatcagct agattaattg gaaaagaaga agcattaaag tataagcttg actccgttgt
    29641 aagtaaaaag gttgataaaa taaaagaaca acaagaaaaa atattagata aagttatagg
    29701 ggtaactaca aatactctag atggttcata tgaaaatgta aggacaaaag aaactaattt
    29761 gggtaattta ataagtgaca ttttactaga taaaactaag gctgatattt ctttatttaa
    29821 tggagggaat attcgagata cgatagaaaa aggcaatata acaagaagag atattgtaga
    29881 tgtatttcct tttagcaata ctatagttac caaagaactt acaggagcac agattaaaga
    29941 tgtattggag catggagtaa aactttatcc agaaaaaagt tcagcctttt tgcaagtggg
    30001 aggaatttca tattacttta atcctaaaca aaaagaaggc gaaaaaataa caaatattca
    30061 aaaagaagga aagccattag atttaaataa aaagtatgta gttgcaacga atgattatat
    30121 agcatcaggt ggagatgaat ttccttgttt ttcaaaagag ccagtactaa aggaatttgg
    30181 aaatttagag agtgcagtca ttgaatatat agagtacaaa aaagaaatat caaaaaatgt
    30241 agatggaaga attggtatta aatctaaaga tgagttaata agcaagaatc atgagagtga
    30301 tttgatatta agtgaaaatg aaaaaaatat caatgataat gaagagaatc tatctaataa
    30361 tataaaaagc tctgatagtg ataaaaataa aagcttagat aaaacaagtt ctagagaaag
    30421 ttctaatcta ggaatatcta aaagagaagc taaagaaaaa tctcctaaaa caggagattt
    30481 aggtttttca aatagtataa ttatatttat agtttcaagt acattgatat gtttattgaa
    30541 ttttaatcaa aaagagttaa aggataaaaa gtcaaaataa aaattaatga gcaaaaatta
    30601 gtagatagta atttaatttt agataatagt aaacagcaaa ggaaattagt tatataaata
    30661 ctaatttcct ttgttttatg ttttaacatg attactttta aataaaattg tattttatga
    30721 aaaataatta tactaaatgg catagtatta tggggatttt tagtttttat tcaagtaaat
    30781 gaaatcatat taacaacttc tgatatattt acaaattgat aaaaaaatga ttttattagt
    30841 atgatataat ttagctagta tgtatgataa tggaggatat agggatgaat aatatattac
    30901 ttttggaaga tgacaaatct ttaaatagag gaattagttt taaattaaaa aaagaaggat
    30961 acaatgtttt tagtgcattt ggtatagaag aagcaaaaaa tattttcgca aaagaagaga
    31021 tatgcttaat tatttccgat ataggtctac ctgatggtag tggttttgac ttttgtgagg
    31081 agattagaaa gaaaagtgat gtttacataa taatgttgac agctcttgat gaagaggtgg
    31141 atattgtcac aggatatgat ttaggtgcag atgattatat cacaaagcct tttagcttga
    31201 tggtattaat atcaaaagtg aatgcgctta tgaaaagagt aaatacagta aaaaattata
    31261 ctctattagt ttgtgatgat ttattctttt attatataga aaataaatta attataagaa
    31321 cagatgataa ggaagaagag ataattttaa gtaagacaga gacaaaacta ttaaaatatt
    31381 tgatggaaaa ttctatgcag acattgacta aagagcaact gttagaatct ttatgggata
    31441 gtagtggtaa ttttgtagat gataatacga ttgcagtaaa tataagaaga cttagacaaa
    31501 aggttgaaaa aaatccatct gaacctaaat atataaaaac agtaagaggg gttggatata
    31561 tgtggggaga aaggagtata aaaaaatgct aaaaaatatg aacctcaaag atggtttaag
    31621 tgtgaaagat gattatataa tgagaagagt tattgtatat tctgttttat ctgtactaat
    31681 agtaaccctt gtatttatac tttttgaata tagcagatta cataaattgt atgaacatca
    31741 aataaaaaat actcaaaatg ttgctggaat attgattgaa aaatatccta atgatgaaat
    31801 agatatagta aattctattt ataattctga ttatagtaag gtgtctactg gagaaaaggc
    31861 atttaagaaa tttggctatg gattggaaaa taaaatgtca aatgataaaa attttagctt
    31921 atacttaaaa tcttttttta aggaatcatt ttttattttt ttaatgatgt ttatagtagt
    31981 tataggtata atatattatt ttataagata cataaataaa agattgagta aaatttattt
    32041 tatagtagat aagatgtcac aagaaaacta cttgaaggac actactgagt cagaagaaac
    32101 tggttatcta gtagaatata atgaatactt taaagaaggc atatttagta agataaataa
    32161 ctgtctatat gagcttaata gaagtttaaa gataaagttt attaaattag aaaaagaaaa
    32221 agaaagtgta aaatcattag taacagatat ttcccatcaa ttaaaaactc ctttagcatc
    32281 cttaaaatta tacaatacat tacttataga agaagaatta gaagaagatg aagccaacga
    32341 gttcttatta accaataagg cttctataaa taaattagaa aatttaataa attctttagt
    32401 gaacatatca aggttagaaa ttagcatgat aaacataaaa aaagaagata atgatataaa
    32461 aaatactatt ctaaatgcag taaaaagtgt tacccctaag gctaagagca aaagtataac
    32521 attaaattta aatgaattta acagtagaat tataccacat gataaaaagt ggactgagga
    32581 gagtattttt aatgtattag acaatgctgt aaagtataca caggtaaatg gagaaataaa
    32641 tatatctgta gaagaaactg ctaatttctt taaaattata atagaggata atggcatagg
    32701 gattgaaaaa agtgagttta ataatatatt taaacgtttt tatagaggtt ctgctgatga
    32761 aattgaatct gtagaaggta gtggggtagg attgtattta agtagaaaga ttttagaaga
    32821 acaaggtgga aatattatag tttcttcaaa agtaggaata gggagcaagt tttctttgtt
    32881 tcttacaact atgtaatatt aaatgaaagg aaaatgtaag cctctacatt tattatataa
    32941 gtataaacag ctccagaaat aaaaaattaa taaaatatgg agtaatataa cttagaatga
    33001 gaggataatt ttatgaaaat actatatact gaaaatttat caaagcatta tggaaaagga
    33061 gaaagcttag taagagcttt ggacaatgtt gacttagaaa taaatgaagg tgaatttgtt
    33121 gcaataatag gaaaatcagg ttctggaaaa agtacacttt tgcatatgat tggaggtctt
    33181 gatataccta catctgggaa ggtgtatata gataataaaa atatatttac attaaaagaa
    33241 gaagaacttg ctgtatttag aagaagaaaa atagggttta tatttcaaag ctataattta
    33301 attccatctc ttaatgtatg ggaaaatgta gtgttgccaa tcggtttaga tggtagagag
    33361 gtagatgaac cttttataaa agagctttta aaatcattag gacttgaaaa taaacacgac
    33421 gttttaccaa atacattatc aggtggtcaa caacaaaggg tggcaatagc aagagcatta
    33481 gctacaagac cagctataat acttgctgat gaaccaactg gaaacctaga ttctaaaaca
    33541 tctgatgagg ttatgagtat attaaaatct atgtctaaga agtacagtca aactctagtt
    33601 atgataactc atgatgacag tatagcccaa atggctgata gagttatatt catagaagat
    33661 ggcagggtgt caaaggttgg tgataaaaat gattaatact actaaaatag caaaaagtaa
    33721 tttaaagcaa aataaatcaa aaagtattct aataataatt actataatac tttcaacctt
    33781 aatgctttct tctattggaa tttatattgt tgatgcagga gcatatcaaa aagaaaatac
    33841 tataaagtat tcaggtaatt atcaaggtat attagcaaat gtagacgaaa aacaagctga
    33901 tatattgagt aatcatgcag atgttgaatt aactggtaaa atgaatggag taggtgttga
    33961 aaaactggaa gatgattcaa atatttctct agcatacatg aatgaagatg ctttgaaatt
    34021 aaatagtttt gaatttatca aaggaaaatt gccatcaaaa gagaatgaaa ttgtgttaga
    34081 tagtggagct ttaaaggcac ttggttataa aaataaagat ttaggtgaaa agataaaaat
    34141 atcttataat gactataaaa gtgataaaaa aattgaaaaa gagttcatta taagtggaat
    34201 cttaaaaact agcgaaatat ctgaagcagg taaatattat tatgctatta tatcagaatc
    34261 atatatgaga aatactagag atatgtcaca agaagatttt aatatatatg tgaaattaaa
    34321 tgataaaagt aatttatcga tagaacaagc aaaatcaaaa ttaaataaga ttgctaatga
    34381 tgtaggattg gacactatta atgtagctgt aaatgaaaac tatataaatg ctttaaaacc
    34441 agatatggaa acaattatgg gtggagtatt tgtagggtta gtaattgtat tgtctagtat
    34501 tttagtaata tacaatatat tttatatttc aatagttaca aaggttcaag aatttggaaa
    34561 gcttagagca attggtgcaa ctaaaaaaca agtaaaaaat atagtattta aggaagggtt
    34621 catattagcc ggaatagcaa taccaatagg aataatttta ggctatgtac ttgcaaatat
    34681 tataataaaa tcatttatgg atatagatgt aaaatcatca cgattaccag ttatattatc
    34741 ggttgtggta ataagcttta tatctgttgt tttatcactt ttaaaaccaa tgaaagtagc
    34801 atcaaaagta tccattgttg acgcagtaag atatacagga aataaaataa gtaataagag
    34861 taagagaaaa ggatataaaa atataaatct aaagagatta tcacatgcca atttagaaag
    34921 aaataaaaaa cgtacttaca tgacattggc atcacttata cttagtggaa ctatatttat
    34981 aacagtatca actgccttag aaagttttga tgctgagaaa atggcaagag aacactttcc
    35041 ttatgatata gaagttagac tatctggtta tgaaatgaac agtgataaaa atcctaaaga
    35101 taatttgaat attttacaaa tggataatcc tctaagtaaa gattttttta atcaaataaa
    35161 gaacatggaa ggaattaaaa gaatagaatc tgcaagaagt gtaaaaattg gtatggagga
    35221 ctatgatgtt gaatttaagt atgacctttt acaaagtata aatgaaaatg atgtaaaatc
    35281 attaaacaag aatataatag atggaaaaat aaatcttgaa agacttcaaa ctggagatga
    35341 aatagtaatt actcatgttg atacagcaaa agaaatggga gtaaaagcag gagataaaat
    35401 aagattaact ttatatgatg gagataaaaa gataaaaaaa gaatttaaag ttcaagcaat
    35461 agctatgggg gttccaagtt ttggtatagg gaaggatttt attgatagaa ctttgaaata
    35521 cgattcaact agtagcttgg gaatatatac agaagaagga aagtatcaag aaatcaaaga
    35581 tagtatcaag aagattgcta aaaataatgg atttttagag actgatttta tagatagtag
    35641 aattgagtca aataaggcta ctatttcatt tataaagata atgggataca cgctaacagg
    35701 cataataggt gtgattggat ttatgaatct tgtcaacaca atgataacta gcatagttac
    35761 tagaaaaaaa gaacttggta tgcttcaagc tattggtctt actaataaac aattagtgaa
    35821 aatgcttaat tcagaggcaa tgtattacac ttctggaatg atgataggaa gtattctatt
    35881 tggaggtata ttagggtata ttgctgttat atttctaaaa aagactggat tatcttatgc
    35941 aacatattct ttgccaatag taccaatctt gttgatgatt gtgtgtattc ttatagctca
    36001 atttataaca acttatttga taggacgaag ttttaataaa gaatctctta ttgatagagt
    36061 aagatacagt gaataaaata caaatattta tggttagttt aactagcaaa aaacatataa
    36121 aaaaatatag ttaaagagat tcataattaa ataggttaaa gcatagtaca gagcaaacaa
    36181 tttaagcaga tgtttgctct gtattttatt atgtaatcaa taatatatct aatatactga
    36241 tattattcat gttagaaaat gtaccggtac aattctaaaa aagtataaaa ttgtaccata
    36301 taaaatgaaa attttgtata ataatcgtat agaaaataaa taggagctga tatatatgaa
    36361 taagaagatt aattatgcac caggaccaac tgaaactagg gaaaatgtaa gattagcaag
    36421 agcagaaaaa acaacaaatc cagatataga tattgatttt gttgaatttt ataaaaagac
    36481 atgcgagaag tttggtaata taattggaac aaaaaacgat gtttacatat tgagtggtga
    36541 aggaatatta ggtcttgaag cagcatgtgc atcacttaca gaaaaaggag atagagtact
    36601 tgtaattgac aatggtatat atggagaagg ttttaaagat tttgtaacaa tgtatggtgg
    36661 ggagtatgtg cttttttcaa gtgaatatac taaaagtata gatattgatg aattgaaagc
    36721 atttttagat gaggatagta attttaaata tgcaacagta gtgcattgtg atactccaac
    36781 tggcgtatta aatgatgtaa gcaaaatatg tccattactt aaagaatatg gaatattaac
    36841 tgtagttgat tctgtagcag gtatggtagg agaaagatta agtgtagatg aatctaaaat
    36901 agatataata ttaggtggtt cacaaaaagc tatttctgca ccagcaggac ttactatagt
    36961 cggaataagt caagatgcaa aaaattgtat aaaaaataga aaaactgatg taataggttt
    37021 ttattgtaat ttaaatatat gggaaggcta ttatgaaaaa aaatacttcc cttatacaat
    37081 gccaataagt gacataatgg ggcttgataa agcacttgat aatatattag aagaaggaat
    37141 agaaaatgta ttaaatagac atgaaaagat agcttatagt gttagaaaat ctattgagga
    37201 atatggtcta gaactatttt tagaagaagg atattctaat acagtcacag ctataaaaat
    37261 tcctgaaagt ataggagctt tagaacttac tgattatatg cttaaaaatt ataatacact
    37321 tgttgcaaca tcactaaatc aatatatgga tactatttta agaataggtc atatgggaga
    37381 gaatgcaaat ctaaataaaa tagaacatgt actaaatgtt ttggataaaa gtttaagtgc
    37441 attaggattc aaaggaaatg gaaatttgtt aaatttattt aataagtatt atttttaata
    37501 gataggggga tatagtatgg aagttacagc taagcaaaaa tttacaacga aagacatggt
    37561 ggaaacctca ctattaatag cattagtatt tattgcaact aaatttataa acataagatt
    37621 accaatatct ataaatggtg ggcttgtgca tttaggaact gcaatgttgt tcatatcagc
    37681 aatagtattt ggaagtaaaa aaggtgcttt atcaggagct attggtatgt cactttttga
    37741 tttgatatct gggtggactt tatgggcacc gtttaccttt atagttagag gagttatggg
    37801 ttatttactt ggaaagattg catgggcaaa tggtaataat gggaataatt ttttaatcaa
    37861 tgtaatagga atatgtgttt catcaatttg gatgctattt ggatattatg taacagaagt
    37921 tatactttat ggtaatttta tagtacctct tacttcaata ccaggtaatt taatgcaagt
    37981 attgataggt cttataatag cgcttcctat ttctaaggta ttgaaaaaat gtataaaata
    38041 aatataaagt gaactaaaat ttatgatagc ataaattata ctgtataata ttaggatgga
    38101 gtacataatt aaaaaatttt agtatagagg ttagttcaca atgttatcag ttacaagata
    38161 ttcaatcaaa aatgttcgtt taaagccgtg ggtaaagttt atttggtatt ttgagacaaa
    38221 atcaaatata ctgttaaata ataagttact tccgacagac agtatagata ttattctcaa
    38281 tctttctgat gttatggaat ataaaattga aaatcaagac tatattgcta gtaatattca
    38341 ttttaatgga ataagggata aacatggatt tattattcaa catggaaata tacgtgttat
    38401 agggatttct ttttatccat ttggtctcta tccattttta aagataccaa tttcagagtt
    38461 taacagacaa attgttgacc tagaagcagt atcaaaacta tttgcaaaaa aattagaaga
    38521 gtcattaaat ccaacaaaag caatagaaaa agttgtttta tgtttagaag aagtattatt
    38581 atccatatta gaagaagatt taatttcaaa taaatatgta aagcttctaa attcatttat
    38641 atatgttaat agatatagca atataaaagc attttgtgat gatacaaata taaatattaa
    38701 aacattggaa agaatctgtt taaaatatac agggtataca cctaagattt taaagagaat
    38761 ttacagattt aaaatggcaa gcaatcaact tatttataat tataaagatg atgaactttt
    38821 tgattttatt tatgaaaatg agtactatga ccaagcacac tttataaaag aatttaaaaa
    38881 attttcaggg acgtcaccaa ttaaatttag tggtgagaat aagacgatta aagaaaatat
    38941 aaagtacagc tatttataat tatactgtcg attttttaca atacctccaa tttatttttt
    39001 gatatgatat aggaaaataa attggaggtt ttacatatga aaattattac agaaatagtt
    39061 gagtttaatg tggaagaaaa tttatcaaaa gaagagttta tagaaattgt aaatgactta
    39121 gaattaaaat ttcattctat tcaatctggt tttattgata ctgagctttt atatgatgaa
    39181 aagtctcaaa agtggattat gatacaacat tgggaatcta tagaagacct caagagtgtt
    39241 tctagtaaaa tgtttaaaga ttcttcaact gagaaattta gaaaagcttt aaagaatcaa
    39301 actgttaaga tgaatataat accacaaatt aaaagttgga aattatagaa ctgaatgtaa
    39361 aagatagtta aatagtatca aactaaatta gccaaataac attttgtatt taaattgtta
    39421 tttggctttt agtgtttatt ttaatatgag tgttatatac tagaaaaacc aacaaactgt
    39481 tagagtgtgg attatcataa tgtcatattc gggagctaaa aggcttaata ctgatttgcc
    39541 aattggtcaa tccatgcatg tccatctgga tatgctgtta ttaaagcatt tacaagccaa
    39601 tccctttgct cttgtgataa tagtgggact gttacatcga agtctttttg ataaccaagc
    39661 ctatctatgt atattgattt gcaaaacaaa accacttcgg gagccatata tgggatatta
    39721 tctgatgtta tcagtctggc cttatccata tctcttataa ttctttgatt ttgggaaaaa
    39781 agaaattttc catctttctg tggattatat atcaattcaa taaaatcgaa ctgtaactgt
    39841 tcgtcacact gtatattcat tttatagtta tcatcctcga ctttttttaa ttcaataaat
    39901 gagcaatcag gcttaatcgc aaaaacacaa atttgctcta tatgttgctt gttaaggtcg
    39961 ataataggtc gtaataaata attacccaag ggctcatata tatcccatcc ttgattaagc
    40021 atatactgaa tgctcttttc tttatctgtg tcagaaatcc atatgtcaat atcactgtgt
    40081 gggcgaatat gcatattcgc aaataattct agggcatatc caccacatat tgaatatgaa
    40141 aagccacaat cattaaaaaa gtttacacaa tctttaatta gtttgttcat agcaacctcc
    40201 ttttgcatgt actgaaataa attaaatttt ttaaaatacc aactaaatgt ttgttttgtg
    40261 taaatataaa actgccgata ttaaggcagt tttatattta ctatttagaa aatttattaa
    40321 caaatttttg atattcacac attatcttat cattcataaa agaaataccc ataaaagcag
    40381 cttgctcacc aaacaaagta aaacgttcta tcatctgttg tggattacct ggataaactg
    40441 ttggaataca ccatgtgttt agaagaaaac caaacatttg agcagcaatc tctggatttt
    40501 taacttccat agaattatct tgatttcctt cttcaatcaa tgcttttatc caaggcacaa
    40561 tatcatttat aatctcatca aactgcgtag ctaaatactt aggattacgc aatagtgatg
    40621 atgacattaa aaaaatgtct tgtttattgt gctgttcata agtatgaagc aacctatatt
    40681 gtaatttttc taatgcggtc tttccttcat cattttttac ctcataccca taaaatccat
    40741 cattatacaa ccgacttgtg attgccttaa ttatttcgtc ttttgattta aagtgatgat
    40801 aaatagcacc tcttgaaagg ccatctaaat tatctacaat gtcttgaatc gttgtctgct
    40861 catacccttt ttctaagaat aacttatgtg aaatatcaag tattttttgt atagtattat
    40921 caggttcttt ttttcttccc aaaaaactca ctcctcgaaa caatcatttg gtatgtttat
    40981 cttagcaaat acataatgat ttgtcaatgt gtctttttag catgttgaac aggtatattg
    41041 ccatgctttc attattttat ttttttgcct tatactggac tatatttgca gtttcctaat
    41101 atatttggct catatttaaa taccattatc taaaagcact attgctgtac gagaggcaat
    41161 aggcatttta gaagaaggag gagttgagct aaagtataca tcataatctc ttaagttttc
    41221 tttttttgtg tttcctccaa actctaccat atcagtattt aatatcgttt tgtagtttgt
    41281 attttgaaac tttgaaatat caactgattg tattagatta gggtggaaat taaatataaa
    41341 taaatatttg cccttactgt acaccaaaat ctttttatca ttatccatat gtataagttc
    41401 atgactattt tggataaaaa tatcactgta ttttgtaagt tcgagcatag atttatcaaa
    41461 atttaataat tgtttatact ttaagttgtt atcttctgaa aggctccatt gtcttctggc
    41521 atacttatag ctccaattgt tgccttctcg tggaaaatca atccactcag gatgtccaaa
    41581 ttcatttccc ataaaattta gatatccttc acctgctaga gaaaaagtta ttaatttaat
    41641 taatttaata agagatattg ctctattgat aacatggtta tttgagttta tttccatatt
    41701 ccagtacatt tccttgtcag ctagccaaaa aataattgtt ttatcgccaa ctaatgcttg
    41761 gtcatgggat tcacaatatc ctatattttt ttctccaggt cgtctagtag taagttcata
    41821 ccacattttg cccaaatccc agtcttcatc agataagtta gagatagttt ttatccaaaa
    41881 atcaggtact cccattgcga gtctatagtc aaatccaatt ccgccgtctt ttatagggat
    41941 acacatacca ggcattccac tcatatcttc tgcaatactt atcgaattag gtttaatttc
    42001 tttcattaat tcatttgcaa attggagata tgttatagct tcaatatctg tattcatact
    42061 aaaatatttt tcataactat caaatgaaac tccaagacca tggttatgat ataacattga
    42121 agttacacca tcaaacctaa agccatcaaa atggtactca tttaaccaaa attttatatt
    42181 tgaaagcaaa aaatgtatta cttcaggttt accatagtta aaaagttttg taccccaagc
    42241 aggatgattt ccctttgaac ctgagtggaa aaattgatgt tcacttccat caaactcatt
    42301 tattccttct aaagtattct ttacagcatg agaatgaact aaatctaata aaacagcaat
    42361 ccccattgaa tgagcagtgt ttatgaggtt ttttaagtct tcaggagtac caaacctaga
    42421 tgagattgca taaaagtttg aaacttggta tccaaaagat gcataatatg gatgttccat
    42481 aatagccata agctgaatgg tattgtatcc agcttttttt atcttaggaa gtattttttc
    42541 agtaaattca ttataagttc caatagattc gctttcagta gacataccta tatgacattc
    42601 atagattagt ggagaagtta tgttttttaa gtcaaaatca ttgtcagtcc agataaatgg
    42661 agtttttggt tgccatattt gtccattaaa tccaccaaaa tctttttgaa ttactctttt
    42721 tatatataat ggtatacggt caaatgtttt tccatttgca gtaacttgta cctttacctc
    42781 tgatttgtga ggtaagctat tttgaccagg aataaatatt tcccaattac cagacccaat
    42841 ttttcttaga ggatgagatt ttctattcca attattaaag tcaccaatta gtgacaaact
    42901 atctgcattt ggagcccatt ccctatagaa gaatccatca tttgtctgat gaaatccata
    42961 gtaaagatga gcatttgcaa aagaactaaa atctttatag tttttcaatg tttttgattt
    43021 catatcctca taatgtttca ttcgcttttt tatatcagat tcaaatggtt gtaggtatac
    43081 atcaatatct aaaattttaa atcttttttg acttttcatt gtatttctcc tccataataa
    43141 atattacatc taaaaaataa tatttatctc atactatctt ctctgtataa ttgatatata
    43201 ttatataatc ctaataaaaa gcttaagcca ccaatgatta atttcataat ttacctccct
    43261 agtatttata cttatatatc gtattcatca aaatttaaaa gtttgtttaa aactctttta
    43321 ataatatcat aatcaaagcc tttataggaa agatgttgag aaattttttg atatattttc
    43381 tttttatctt ctttctttac tctttcatac cttttttttg ctagatacat agcattttca
    43441 aattcagtgt ccttgtctaa ttcagatact gcttcattga ttgtacttct attgatacct
    43501 ttattatata aattctgctt aattctgttt ttgccacatt tatttaggtt aacatttgtg
    43561 ttaacaattt tttgagctaa tacactgtca tttacgagat tataactttt aagaaaatct
    43621 atgaccctct caattatatt ttcatcaaat tctgatgata gtttttcttt taattttttt
    43681 tcagattggt cagcatgaga taaaatattt aatgctttat ttttagcttt tatatacatt
    43741 tcatcatcta aaataggttt taattcttct tcatttattt cattcccttt ttttaaatta
    43801 aatgtataaa ccagttcttt aaatatagca ataaaaaatt tatcatctac ataaatatta
    43861 actctatcat catttctttt ttgttgttct atttttgtaa ttatacccat aagtcctcct
    43921 tttttatatg taattatatt aacaaaagca actaataaaa tttaacaaaa aacttatatt
    43981 tgtatgttat attttatcaa aattaagaca aaatagtaaa aagttatttt tattaaaaag
    44041 taaagcagaa ttatgttaaa taattatttt ttaaagtgtt ttttagcata taaatataat
    44101 tatataccca aaaaaacaaa ttataagctt taagaaataa aaaataatgg tacaatagta
    44161 ttataacatt aaaaggagac aaaatatgag aagtgaaaat ctagttaaga tggcagagtt
    44221 gaaaaatact gaaaaactag agaaatttaa tcgccataaa ggcaaaatca aaataggtat
    44281 attgggaggt acttttgacc ctatacacta tgctcattta gcaacagcag aatttattag
    44341 agacaagtat gacattgaca aaataatctt tataccatca ggaaatccac cacataaatt
    44401 atgtatcact acagataagt atgatagata taatatgaca cttctagcaa ctgaaagcaa
    44461 cgaagatttt ttagtttcaa aagtagaaat cgaaagaaag aaaaggactt atacaataga
    44521 tacattaaaa tacttaaaga aaaaatacaa aaatgcagac atttatttta taacaggtgc
    44581 agatgcaatt tgtagtgttg aagagtggaa agatgtaaag aaaaactttg agttagctac
    44641 ttttatagcc gcaactagac caggaattag tttgttaagg tcacaagaga ctatagaaaa
    44701 actaactaag aagtataatg ctgacattat aacagtttat gttccatcac tggatatatc
    44761 gtccacatat ataagggaac agctaaatga aggcaagtca atacgttact tagtacccga
    44821 aaatgtagaa aattatttat atgaaaataa actatatcaa tatggagatg attaaatgaa
    44881 cttagaaaat attaaccaaa gactaaatca aatgctacca gtggggaggc ttagccattc
    44941 aaaaaatgtt gcaaaatgtg ctgaaaaatt atgtgagatt tatggatgtg acaaagaaaa
    45001 agcttactta gcaggaatga ttcatgattg tgcaaagtat ttaagtgaca aggaaataga
    45061 ggattatgta aataagtatg aaatatattt agacccaata gaggatggaa atcgttcctt
    45121 gtctcatagt gtaattgggg cgtacatatg cgagtatgaa tttgaagtgg aagatgaaga
    45181 tattataaat gcaatcaaat atcatacaac agggagagag gacatgtctc ttttagaaaa
    45241 aataatttac atagctgatt taattgaaga aggaagaaaa ttcccagttg tagatacatt
    45301 aagagaatta gcatatggag ggaagcttga tgaagcactt ttaacttctt ttaataatac
    45361 tttaatgttt gtcatcaata aaaaagaaga gatacatcca agaacagtta tggcaagaaa
    45421 ctatctaatt aaagaaaagt tattataaaa aagctatata aaggcaaaca tattaataaa
    45481 tttaaatttg actatgttac aaaatcgtat taatatgtta caataactaa gtgtatttta
    45541 attaggaaag tgaggaattt ttatatgaca gtggaacaaa tgacaaaaat agcatatgat
    45601 gccatagaag ataaactggg tcaagataca gttataataa atataggaaa agtttctagt
    45661 ttgtgtgatt attttattat tactacagca tcttctcaga gacaggtaaa agctattgct
    45721 gacaatgtgg aagatgaatt agcaaaacta ggattagagc caagaggtaa agaaggacaa
    45781 ggaactcaaa cttgggtact ccttgattat ggagacataa tggttcatgt atttaatgag
    45841 gaaaatagag ggttttataa tttagaaaaa ttatggaaag atgcacctta tatagatatt
    45901 gacacattag cataaacatg ataatatatg ttattataat tagaaaattt caaaaattat
    45961 attaaattga atagactaga gcagtaaaag attatatttt ttcagagagt tagtggaagg
    46021 tgagaactaa tattatataa ctttgaactt actagattaa aatctattct ccatggctgg
    46081 attaaaagct atctaagaga gtctatatat gtagtaggct aattagggtg gtaccgcgaa
    46141 gatttatcct cgtccctaaa cgtaagttta gtgacgagga ttttttattt tcaaagaatt
    46201 atttggaaat tataagtaaa taatactaaa taaggtagtt atacacaatt aaaaatagga
    46261 ggcaaaatat gagcgtatat aattttaaag aagtagaatc gaaatggcaa aaaatctgga
    46321 aagataataa tcagtataaa atggatactg cacaaactga aaaacctaat tattacacat
    46381 tagaaatgtt cccttatcca tctggaaaaa tacacatggg acatgttaga aattattcta
    46441 taggtgatgt tgtcgcaaga ttcaaaaaaa tggaaggata taatgtactt catccaatgg
    46501 gatgggattc ttttggatta ccagctgaaa atgcagctat aaaacatgga atacatccac
    46561 ataaatggac aatggaaaat atagaagaaa tgaaagagca attaaattta ttaggtatta
    46621 gttatgattg ggataaagaa gttgcaactt caacgccaga atactataga tttacacaag
    46681 aaatattttt gaagttttta gagcatgggc ttgcatataa gaaaaaatca tatgttaact
    46741 ggtgtccttc ttgtgagact gttcttgcaa atgagcaagt tgttcaagga gcatgtgaga
    46801 gatgtaaagc aacagtatta aagaaagatt tagaacaatg gtattttaag actactgaat
    46861 ttgcagaaga attacttaat gacttagata tattagatgg atggccagaa aaagttaaaa
    46921 caatgcaaaa aaattggata ggtaaaagta caggagcaga tttagttttt gatatagatg
    46981 gaactgataa atctatgaca gtatttacaa ctagaccaga cacaacttat ggagttactt
    47041 atatggtact tgctccagag catgaattag ttaaagaatt ggttgcaggg actgaatatg
    47101 aagcagatgt tgaagctttt gttcaaaaaa tgcatactat gacagaaata gaaagaacag
    47161 cagctgatgt agaaaaagaa ggaatgttta taggtagata tgttataaat cctttaaatg
    47221 gcaagaaagt tcctctatgg atagctaact atgtattagt tgagtatgga acaggtgcta
    47281 taatggcagt tccagcacat gatgaaagag atagagattt tgctgaaaaa tataatttag
    47341 acataattga tgtaataaca gaagataaca aaatgataaa ttcagaagaa tttaatggat
    47401 tagatgcttc agaaggattt gaaggaataa tcgataagtt agaaaaagaa ggtagaggaa
    47461 agagaacaat taattataga cttagagact ggttagtttc aagacaaaga tactggggtt
    47521 gtcctatacc tgtggtttat tgtgatgaat gtggaatagt tccagttaaa aaggaagatt
    47581 taccagttct tttaccaaca gatgttgaat ttactggaaa aggggaatct ccacttacga
    47641 cttcaaagca atttatgtca acaacttgtc ctcactgtgg aaaaccagct agaagggaag
    47701 ttgatactat ggatacattc gttgattctt cttggtattt cttaagatat gtggatagca
    47761 ataatgaaaa tgaaccattt agtaaggaat tagttaatag atggcatcca gtagaccaat
    47821 atataggtgg agtagaacat gctataatgc atttacttta tgcaagatgg tttgtaaagg
    47881 catttaagag tatgggaatg gtagacttca atgagccatt taaaaactta cttactcaag
    47941 gaatggtact tatggatggt tctaaaatga gtaagtctaa agggaataca gtatctccta
    48001 tggatataat agatgagtat ggagcagata ctgcaagact tttcgtatta tttgcagcac
    48061 caccagaaag agatttggac tggtcagagc aaggtgttga tggatgcttt agattcttaa
    48121 atagggttta tagattggtt gacgagttag cagatgtggt taaaaaggat gtagagtttg
    48181 gagaattaaa ttcccaagat aaggatatga gatatactat acactctaca cttaaaaaag
    48241 ttactgctga tttaagtgaa aaattcggat ttaatactgc tatatcagct cttatggaat
    48301 taataaatga tatgtataaa tataaagagt tagataatat aaacgaagca gttataaaag
    48361 aaggtgtaca aactatagta actataattg caccatttgc ccctcattta ggtgaagaac
    48421 tatggactat gataggtaaa gaaggaagtg tatttgacat agactggcct aaatatgacg
    48481 aaaaagcttt agtaaaagat gaaatagaag ttgttgtaca agttaatgga aaagttagag
    48541 gaaaattaac tgttaactca aatatatcta aagatgagat ggaaaaggta gctttagaag
    48601 atgaaaaaat aaaaggatta gttgaaggta aaactatagt taaagttgta gctgtaccta
    48661 aaaaactagt aaatatagtt gttaaataac tcaaaaatat gaacaaaaat ataaatttat
    48721 aaaataaacg aggctgtctc aaaatagaga taagcctttt ttcattgttg aaattataaa
    48781 attgttgaaa ttataaaaat agatttgatt ttatacaaaa aaatgattaa agaactaaaa
    48841 agttcattct tatataccct agttgttgtt ttaaatatta ttataattaa tgttaaatcg
    48901 agttaatgta ttaagtggta tgtaaatcat tcagtttcca aagtgttgtt catcaaggaa
    48961 ctgctctaag cttaaacgaa aaaaatataa ttattgtatt ttgaaatttt tttctatata
    49021 atgaaaacag gcaaaaaagg tgcgtatcta tgctttatat gaaacaccca gacaacgaaa
    49081 ttcagattca tataatagct accatgtttc taaaaaggaa cttgtaaaaa agatagcgtt
    49141 tcaacttccc agttgattaa aattatcagc aggaaaacaa gtatggtcag cagtggtatt
    49201 ctaatgggtg ttgtcgatat atccaagttg ggattgtctg aggatgttat caaataactt
    49261 gtgataggtg cagtagatgt ggagattcct gatacggatt tattctcagg ggatggttgc
    49321 ttcgggagat atggagcgta accagtttat tgatatggta accatttttt gtctaatttg
    49381 atgaaagaat cccaagaata ccatacagaa gtaagacagg aattaactgg tggtataaac
    49441 tgataaaggc aaatttaaaa attttgatag gatgatttta agatttatct tctattttgt
    49501 gttttagaaa taattgaaat gttatgagga ggtatgtaca aatggagact gtaacaaata
    49561 atcaatcagg tgtagaaatt caactcagtc tgtttgaagc tatcaaagat ttattgttaa
    49621 ttaatcctat tttcttgttg ggaattatct tgattggtat tttcttagtt gtaatattca
    49681 agaaaaatag tgatattcca aaggtaaaaa catctatttt atcactggca atgtattact
    49741 acttatgttt aacactatcg catattgttg gtatccctac attcagtgaa tatataagac
    49801 tgtcacagtt aggggaaacg ttctttaatc caaacataaa tcttattcct tttagtgatg
    49861 gatttagttt gagttttatt ttgaatattt tactttttgt cccattaggt tttttatgtc
    49921 cgcttatcag caaaaccttt gaacgtttga gaaatacatt cttgattggt tttggattat
    49981 ctctttttat cgaaactatt cagcttttta cgttacacag agcaaccgat atagacgact
    50041 tactcacgaa tgtaattgga acaataatag gctatttctg cttcaaactg attgctaaat
    50101 tgcgaattgt aaaactacat tcagatgatg actctatgga acaggattac acagtatgta
    50161 ttccgattgc cattataata gttgccctta tattaggatt ttttagttaa gttccaaata
    50221 gctaatttgg gaattatgga ggtcattaag tgaataaaat tacttttata tgtttaggtg
    50281 taaaaagtat ggagaagtca attaaatttt atagagatgg attaggattt tagattacaa
    50341 acttttagtt taccaaggag atagcaaagt tgtgtgccaa agggtaacca tttggaaatc
    50401 cagacaacat aacagatagt acgttacctt ttacaggagc atactatctg ttatattgtc
    50461 aacatcctat tttatggttt gtgtgtagtt tcctgtaaac tgaactaaat aattaaatag
    50521 aagctattag aattaataat aacagataga tattaataag cataaacaaa tagtaaaatg
    50581 tgtagatata gacgttttta agtgaaacta ttataaaata attgactgat aatcaactga
    50641 caaaacctat ttttttaggt ttaactgaca tttaactgac agtcagtttt tactatttaa
    50701 atagaagttc gcttagattg tcggaagctt ctttgtccat ttctttaagt acatgagaat
    50761 atctattcat agttattttt atatctgtat gacccaatct ttcagaaaca actttcatat
    50821 tagttccccc taaaagcagc agagtggcac ttgtatatct taaatcatgt attctaatct
    50881 tttttaaatt attttttttg taaaattgtg aaacgttttt cttagtgaag aaggtagaaa
    50941 cggatttaaa ttggtgttta gacaaactaa attatttctg ttttccagga taccttacaa
    51001 ttttaatttg ctttgtctta gttttttaat tttcaatttt tcaattaatt cttttggagc
    51061 tgataaagct ctttttgatt ttggtgtttt tggctcttta aaagatattt tgccattaga
    51121 atagacaaga atttgattaa catttatcag attgttatct aagtcaacat ctgaccacct
    51181 aagcccagta gcttctccca ttcttaaacc tagaagtaac attaaaagaa taggtatttc
    51241 tatattatta ctaagtaact tttctattag caataatact tcttttctat tgtatatttc
    51301 atttgtagaa tatttttctt tagaaggaag ttttataaaa tcacatgaat tttcttgtat
    51361 ttctcttaat ctatatgctt cccttattac agaacttaga aagctatacc ttactttagc
    51421 actagtaaag gtagaattat taaagttata atttacaaaa gcttgtactg aactaggatt
    51481 tacttctgtg agttttagat tcttaaaaag aggttctatg taatttttaa cccaagattt
    51541 tgtatttgta acagtatatg gagaccaatt atttttattc atgtccatgt atttataaca
    51601 tctttctaca aatgtcatat cttttggagc aacaaactta ttattgttta tagtagattt
    51661 tatttcaatt aaatgttttt cagcatcctt tttcttttca taacttccat aacttttctg
    51721 ttttatcttg ccagttgttt cctctatgta ctccacatat acatagaatt tttcccctct
    51781 ttttcttata aaagctgatt tgatattcat atatgtacgc tccctttata agttagtttt
    51841 ataaaagaac agttgtacta ctctaattat gtcattatct ttttaattct ttacagttac
    51901 attataacac gtatttgtat acacttaaat taacaggaag ataaatatcg ttaaaggagg
    51961 aaaagaaaat ttaatgtaga attattaaga tatatagtat ttcatatata aaagggggag
    52021 atattgtgaa attaaagaaa ttattatcac tagggttagt gtcaatgttt gttgctggtt
    52081 ttcctatatc agctaatgca cttgataaaa ttgataaaat tcaaggagca gataaatacg
    52141 aaactgctgg tatcatagct gacaaacaaa gttatactac tgcaatactt ataaatgcag
    52201 atagtacaat ggctgatggg ctaagtgcga gtggacttgc aggagcaaca aatgcaccaa
    52261 tccttttgac taaaaagaat aatataccta atgcaactct taaaagagta gaaaaagcta
    52321 aaaaggtata cataatagga ggagaaagtt ccattgataa agcaacagaa acttttctaa
    52381 aagataaagg aatagagact agaaggcttc aaggtaatga taggattaag acaagttata
    52441 atgtagcaaa agaaataaat tccattaata aagtaaataa agtaatatta actaacgctt
    52501 tcaaaggtga gccagatgct atgagtgctg cacctgtagc agttagagat aaagcagcta
    52561 tagtattaac tgatggaaaa agtgttccat ttaatacaac tggtatagaa agttatgcaa
    52621 taggtggcac ttcatcaatg agtgatagtt tagtaaatga tactaattca actcgattgg
    52681 gtggagtaga tagatatgat actaataaaa aaatagtaaa taagttctat aatggcgcaa
    52741 aagaatttta tatagctagt ggtactgatt tagtttatgc tttagttgct tcaccaatgg
    52801 ctaaaaataa tcctattgta ctagttgata ttggaagtaa taaagatata cttaaaaatg
    52861 ctgcaaaagt aaccgggata ggaaatctaa gtgataaaat tatgctagag tgtgaaaata
    52921 ccatcaataa tattagtctt ccatcttcaa ataaaaatat aatatgtgga ttaaagattg
    52981 attttgattc aaatcacata atttggcaag ataaaggaag ttatcttgaa tgttatgatg
    53041 ataaccttga atattatact gaaaaatata aagacccaac agttcctata aatatagaaa
    53101 atacaagtac acaaaattta gatgtaacaa aattaaaagt ttatggagaa gctaattcaa
    53161 cattatatat ggggcaatac gctaaaataa aaatggattt taatagtttc ggtgtattaa
    53221 agccaggaga aaaatgtact atttatttag atataatttc attagatcca tcaagaagca
    53281 tgacattaac attttcttat gtaggtgata aagaaaatta taaatatgaa caaggattgg
    53341 caagtagaat attattttat aacccggatg gagaagattt ttttgaatat aaataactag
    53401 tgggtatgta aatgtctcga tattgctcat atgttgagtt attatattta gtttcatatg
    53461 aactatatgg attttaaaat taaaaatact taaaaacatt tattttaata gtaggtgttt
    53521 ttttgattaa aagaatatta ttataatgta aaaagtaata aataggtaaa atatgtaaga
    53581 attatatgtt ataatatttt tagcaagaag atgtaatcta caatttatag agtggagttc
    53641 atgtatcaaa aaattatcct cccgacgtta agaagggagg tgaatataca tggataattt
    53701 tttacaaggc atactagcaa gtctatctgc tagcttaata gtttatatag ctagcaaact
    53761 atttagaaag cgtaaaaaac cactcaaagc ggcaactaag agtggttggg aatttgattt
    53821 aaaaatcaga ttccataaaa ctaagtaatt tctaaattat gaactccact ctacagcaaa
    53881 atagattgta gttcttcttg cttttattat atcacaaatt ggtacagata ttcaaaaata
    53941 atatttttat gatataataa agtcatagaa attttgcagt gttcgatttt ttgaagaaat
    54001 taaggcttaa cagttgaaat ataaggcatt gaggacttgt gataagtgtt atcaattgca
    54061 ctactcatgg ttcactgcaa atttgagaga tttgtatatg tgtaggcatt ggaaatactc
    54121 aatttatttt ggggttttat attaactata tggaatgtaa atttcatatt ccatgcattc
    54181 tgcttacact taatagaaaa gttttatatt aactatatgg aatgtaaatt atttctagcg
    54241 acttggtcgg ttgctccatt tagcttgttt tatattaact atatggaatg taaatttttt
    54301 caaatctgat atatcgacct taaatttcgt gggttttata ttaactatat ggaatgtaaa
    54361 tgatataaac tttgggagtt cagaagaagg attaaaaagt tttatattaa ctatatggaa
    54421 tgtaaattag agatgaactc agatagaaaa acatgtagat gtgtgtttta tattaactat
    54481 atggaatgta aattcttcaa cagttgtgtt accatctcct acacgcacag gttttatatt
    54541 aactatatgg aatgtaaatt gctacgtaac cagtttcacc gctttcagta tataacgttt
    54601 tatattaact atatggaatg taaattgttg gtatagtttc agaaaagaaa ttcgaaacac
    54661 ttgttttata ttaactatat ggaatgtaaa ttgtatccaa aaaattacaa taatcatacg
    54721 aactgctaat ataagcagtc aatatatgtg tacatttatc tattttatct ctaaatatat
    54781 aaattattat ccccctaaaa aactttcata aaaacaaaaa gaacaatatc tctttggcaa
    54841 ctggctgaca taactcataa gatatttata taagtcttag tctctatagc tttgcgtcac
    54901 tagatttctc tagttttgcc gatttagttt tattctataa ctaaataata caatagaatt
    54961 agttattatt caataagatt gtttgaaaat tgaataaatt tataggtatg aacgtaattt
    55021 cacacttaaa aaacagacta aatacgtaga atatatagaa aaatttacct gtagtttttg
    55081 tgataaaaag ctcctattat taatttaagc tagataagtt tgaggaagtg acataaattg
    55141 aaagaaggaa tatattatgt tgaataaaaa attaccagat gcagaattaa aaattatgaa
    55201 atacatatag aatactggtt ataaaactgt aatatcaaaa gatgttgcag atgaaataga
    55261 aaaaacatat gcttggaagc atacaactac aattacactt ttagctagat taactaaaaa
    55321 aggttttttc atatcgcaga gaattgggaa acatgtacac tatagagtat taataaaaga
    55381 gaaagaatat ctcaaaatag agggaaaaag aatttttgga ggtctacata acaatccatt
    55441 atcagaatta atttcaaaat tgcatgatgg agaagaaata actgaagaaa aaataataga
    55501 aataggaaat tggataaaaa gctggaaaga tgaagattaa taaataaaag gtagctacta
    55561 atataagtgc tacctttttt cttgtggata atattgggga taagttgtgg aaaacttgtg
    55621 gataaaatat tttgctgaca tttaactgac ataagtatta gattttgatt taaaaatgtt
    55681 gaaatatcaa taaataatta aatagaagtt attagaatta acaatagatt cctttttcaa
    55741 agaaatcttt gatttcatca aggttatcag tttttccaag tgctaagata agttttattc
    55801 tagctttttg acctggtaag tccccaccaa atatacaacc aagatttttt aaatctctac
    55861 cagaaccaaa gtaaccataa ctatcgaata ctctacctga atgacatcta gaaactataa
    55921 ctacaggaag tcctttttct ctagcatatt caactccaga aagcatttga ggaggaatat
    55981 tacctctacc cattgcctca ataactatac ctttataacc actatcaaca gcaaatctta
    56041 taaagtcagc attttctcct acatatgctt taaataaggc aactttagat tctaccttat
    56101 cagtatctat aattgttcta tttacaatat ctcttgtaag gacaagttcg ttgcagtcaa
    56161 ttattcctaa tgggccacta gttagagatt taaatgtatt tagagaaaga gtatttgttt
    56221 tagtagcttc agaagctaat aatacttcat tgtttaaaac tacaaggact ccttttccca
    56281 tagcatcttt ggatactgca gtacaaactg atgcagataa attacttgaa ccatcatatc
    56341 caagttcaga actacttctc atagcacctg tgactattac aggtttgatg ttgtcaattg
    56401 taaggtctag aaaataagct gtttcctcta aactatctgt accatgtgtt attacaacac
    56461 ctgtaatatc ttttcttgct aataaatcat ttacataatt tttcaattcc atcattctat
    56521 aaggtgttat gtgaggtcct ggaatttcat caaaattaaa aacttcaaca tctgcaactt
    56581 tatcaatgtt ggtaaccatt gatagtattt gttcacctga taaagttggt atagctgctc
    56641 cgactttatc atctactgtc atagatatag ttccaccagt aaaaactatg gcaacttttt
    56701 tcttaatact catactattc tctgcctttc ataaataaaa tttataattc cgataggatt
    56761 atatcaaaaa aagtagttaa ggtctacata aactctttta ttcatataat ttagatattt
    56821 cagtgtaata taattatttc ttaatttttt gccattcaac gatataacca tttaatatct
    56881 ctcttatggc ttttcctatc ttagtataag cttcatcata tagatttgct agagatattc
    56941 taattgacca ttcaggacca tagaatccat ttccactaag taaaactact gaatagtcat
    57001 tagctaattt ataaagaaca tctactggag atgcagtttt acttataaat ttaaataagt
    57061 cttctccgta gtttaattta gcccattctt caatatcaaa ttgagtgtaa tatgcagcat
    57121 tgtttttgtt ttcattaatt ggaagctcta aagcttcaaa taatagtttt tgacgtctat
    57181 ggcagatact catattgagt tttttgtagg catctacttt gtcaatcaat gcaaaagcag
    57241 agaaaaacgc catttgtact tgctgtggag tagaaagacc agcagtatgg ttgagagcaa
    57301 caagtctgct atcagcaaca actctttcca taaatgaaag gctagaaggg ttaagactca
    57361 tatcactgta acgcttatct actgattttt ttaattctcc agttaaatca tttattttct
    57421 tatcaaaaac atttttctta tgaagggcaa atgtaccaag tctccatcct gtaactccaa
    57481 aatattttga ataagaatat actccaacag tgttgtaagg tagttttgac attaaggatg
    57541 aaaaatcttc tacaaaagtt ccatatacat catctgatat tatcattaaa tctttattat
    57601 aattttcaat tacatctatt agattattac aagatgtttc atccatagct atagaagcag
    57661 gattattagg attaacaacg aataaagctt taatagattt gtcacgaagt ttctctaatt
    57721 ctttttttgt atattgccat gtatgagcac ctttttcatc aacttcatta gcatttatat
    57781 ttaccacttt aaagtcgtaa cgaggaaggt taggtatttc aagataaggt gtaaatattg
    57841 gagtcattaa ggctatggta tctccttttt ttagaagttc atttgccatt aatgaatcaa
    57901 atatatagca catagcagct gtagcacctt caacagcaaa aatttctaca tcaccatatt
    57961 tacctgatat atcatatttc atttcttgaa ctaggtaatc gtgtactatt ttttccatat
    58021 gaggtaacat tctatctgga agtggatagt tatcaccaat aattccatca gctagttcat
    58081 gaacaaattc atctccatca aatccaagtt catttatacc aaagtttata atatctctag
    58141 ctaaatatgc tccaggcata tctatatttt catttataaa tttaaaaaat ctttctttaa
    58201 tacccttttt ttgaggcatt ccagccaaat gacctaaatc ccaattagaa cgagtttcag
    58261 taatagcgaa atgaccaaaa gtaaaaaagg cttctctagc agttgaacaa gtccagtttg
    58321 gatttccacg acctgcatca agtaattctc tgttattttc ttttgcagtg tattttgcaa
    58381 tatctattaa tttgtcctta aattcaaaag ggcttatttt tccatatatg tttttgattt
    58441 ctttataagt atgatttttc atgttaaatt cctccttatg taataagttt cacattttta
    58501 taataaaata aacaagttgc aaaaatgatt atactttaat tataataggt ttatagaaaa
    58561 agtaaagtat gaaattaaaa taataactct atttagcctt attaaatata tgttaaaata
    58621 aaaaatacct tttaataaaa aatgattgtt atataaaata aatattcaat ttaattatca
    58681 ccttagtttt tttattgtat tttattatat atgtatagtt ttctaatttt gaataaaaat
    58741 aaagtaaaac tttcttttat attgaag
//
LOCUS       DAEHWO010000014        58313 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEHWO010000014 DAEHWO010000000
VERSION     DAEHWO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.014"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(<1..335)
                     /locus_tag="KNP54_001112"
     CDS             complement(<1..335)
                     /locus_tag="KNP54_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBF0892028.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVGNKEIKILHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELT"
     gene            complement(328..1377)
                     /locus_tag="KNP54_001113"
     CDS             complement(328..1377)
                     /locus_tag="KNP54_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBF0892029.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLSATNTIAKGVFNIDIPLDSRFNLGE
                     YNYIAIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHKVTVTGVVSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINEVKSNL
                     TINSNSIVVRGEVVG"
     gene            complement(1378..1797)
                     /locus_tag="KNP54_001114"
     CDS             complement(1378..1797)
                     /locus_tag="KNP54_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBF0892030.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLNIEKSKIDGICDD
                     VEALKQTIFLILNTERYEHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFQNVKGKVHCKFTVHSKYGNIKAEKVVSV"
     gene            complement(1802..2062)
                     /locus_tag="KNP54_001115"
     CDS             complement(1802..2062)
                     /locus_tag="KNP54_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBF0892031.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMQIAFGTIESVNPLIVKIEQKA
                     SFEEFFLIQTETFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            complement(2076..4046)
                     /locus_tag="KNP54_001116"
     CDS             complement(2076..4046)
                     /locus_tag="KNP54_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBF0892032.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILQFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIIAYDQLRYFKNK
                     DTYVYSNKTASELIKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMFTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLSLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKNEKQNGPAQSTTSKEDTDMANKINKLLKGKLSNTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDLTYQVQNNNSNTSTNNNNKVSKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFK
                     RGAGINLKRVSADQSKDSRGKLLCNINDVKAGDLVFFAYNKGKGNVHHVGLYIGNDQY
                     IHAPQTGDVVKISSLSGRQKKKHDFARARRFF"
     gene            complement(4039..4734)
                     /locus_tag="KNP54_001117"
     CDS             complement(4039..4734)
                     /locus_tag="KNP54_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBF0892033.1"
                     /translation="MAYDFYLDGVQLPIAPGKLEIKITNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFKDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPSVKIEPK
                     RVDSVNATNTKTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLS
                     KYTIYKGQVLKLG"
     gene            complement(4750..7116)
                     /locus_tag="KNP54_001118"
     CDS             complement(4750..7116)
                     /locus_tag="KNP54_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBF0892034.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMTNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIREADEQQKRFNDDVRKGASSTDKLVENAKRLVA
                     TYIGLRSVGGLINLSDQMTSTNARLAMINDGQQSDGGLNKMIFQSAERARASYLDTAK
                     IVSRVGMNAGKAFSSTKEIVAFAEQLNKKFVIAGATTEETNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIQSIADYLEVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNSEFE
                     KMPYTFSQIWTSIKNNAIMIFGVIQKKIEQAMSSRGFRTFIDNFIDSLYVLGAVAFSI
                     FNGIINILGSPFFQAFVNAIIVGVSLIVQVLGWVITQALNITNVFAQNWSIIAPIVLG
                     VAAAMLVYNNALLLSIANKVKDIALSAKTLAMNFAHIIAESYRAAALVASTIAQDGLN
                     AAMAACPITWILYGIIAIVVAFFVAIAVINKFAGTSYSAIGIVAGALSGLTAFIINSV
                     FFWINVFISFAEFFTNVLDHPVYSVKKLFFNLATAVLNNLISMTKGCDEFATNLANSI
                     IDGINGALKAWNKFVDVLNKFGGLGDKLGLGKADMVGHTKSITSTLQKAKGDLNKWLG
                     AEPKGYKSFKQLEYNNVGDWAKNGYAFGQNLENKIKDTFDISKIADKAKKDLGLDDLW
                     DDKYGLGDGIGSAGLNSPLGDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQET
                     INRFTGVNIKIDMNNTNNINKDADLDGIVNVLTEKLNDAMVVSAEGVV"
     gene            complement(7194..7754)
                     /locus_tag="KNP54_001119"
     CDS             complement(7194..7754)
                     /locus_tag="KNP54_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein L7/L12"
                     /protein_id="HBF0892035.1"
                     /translation="MFCSNCGAEITGIGKFCSNCGAAVENEIIEDNNIKSNDLIIDAN
                     GIEVNMTEIYRKYRKEKVNAIKNVMEISGLNIKEAKKIVDSSFEELKNNFIDDTMSNS
                     EKEKITNNQNRKNNIEKAQQESVACCPKCGSTSLTAQKKGFGIGKAVVGASLTGGIGL
                     VAGNLGAKKVRVTCLNCGKQFWAGKK"
     gene            complement(8217..8657)
                     /locus_tag="KNP54_001120"
     CDS             complement(8217..8657)
                     /locus_tag="KNP54_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBF0892036.1"
                     /translation="MSNLSAFLSQNAIKNENVMYVASDRFLDEGGKPVEWELRVLSSE
                     EDEVLRRNCTKRVKVIGNNGKPTGQFTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTTFEDKVEEAKN"
     gene            complement(8726..9202)
                     /locus_tag="KNP54_001121"
     CDS             complement(8726..9202)
                     /locus_tag="KNP54_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBF0892037.1"
                     /translation="MAKNITMKSKDAISASLAECYVTIEGKRYLLMQCIKVEAKFKKN
                     KSKIPILGQTGKGNKTTGWEGTGSATVHYNTSIFRKLMLRYKETGEDIYFDMQITNED
                     PTSSVGRQTIILKDCNMDEVTLAKFDADSEYLDEDIDFTFDDWDMPEEFKILLGMI"
     gene            complement(9223..10533)
                     /locus_tag="KNP54_001122"
     CDS             complement(9223..10533)
                     /locus_tag="KNP54_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBF0892038.1"
                     /translation="MALGGGTFVTQNKVLPGAYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEIFTVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATAKYSGTRGNDLKVIVTTNIDDNTKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDTTLEASAGLVFTGGTNGESVTGAEYQAFLDKIESYSFNALGSLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKVKDTGLLESSLVYWTTGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKSGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS"
     gene            complement(10534..10710)
                     /locus_tag="KNP54_001123"
     CDS             complement(10534..10710)
                     /locus_tag="KNP54_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892039.1"
                     /translation="MNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINNFMKGVS"
     gene            complement(10703..11140)
                     /locus_tag="KNP54_001124"
     CDS             complement(10703..11140)
                     /locus_tag="KNP54_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892040.1"
                     /translation="MLNNIIDGISIKLDKSFGNEYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRTLKKNSFDVHYFPRSKDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNDTEKMNDVELFGGLKRGDNFE"
     gene            complement(11133..11558)
                     /locus_tag="KNP54_001125"
     CDS             complement(11133..11558)
                     /locus_tag="KNP54_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBF0892041.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIERKLLILLKGVFDA"
     gene            complement(11558..11920)
                     /locus_tag="KNP54_001126"
     CDS             complement(11558..11920)
                     /locus_tag="KNP54_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892042.1"
                     /translation="MMDKTRKAIEMLYRDKCTIIEYQPVKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNINSTEEGKVAKLAQTIKLFISPNISVKAGSKLIITTQNNITREYVRSGES
                     AIYPNHQEIILELFKDKA"
     gene            complement(11920..12264)
                     /locus_tag="KNP54_001127"
     CDS             complement(11920..12264)
                     /locus_tag="KNP54_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBF0892043.1"
                     /translation="MEVERLKKLLGISKEDYSKEMILEFILEDVEEIVKNYCNVSVIP
                     EGLNSTVLRMAIDMYKNENLGSEDIALGSISSISEGDTSVSYRSSASEFKESLLKDYK
                     SQLNRYRKIRWK"
     gene            complement(12275..13294)
                     /locus_tag="KNP54_001128"
     CDS             complement(12275..13294)
                     /locus_tag="KNP54_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HBF0892044.1"
                     /translation="MARVEELLSVQELINYTKTRKLKETMGDLLFPTQKIEGLEIKMI
                     KGASNLPVSASVHAFDTEAEIASREGANLSIAELALVKRKIKLDEKDIIVLEEPRNSQ
                     EETQMINQIFNDVDNLVSSVNTRIEAMRMEVLSTGELNINENGVKASLKYGTPTNHKE
                     TKTWSSGTPDILGDIYNMTDKIVVDTGFTPTRSLTSKTILNIILRDEKLRKAIFGVNS
                     DKLLTLNELNTFLVSQSLPPIFTYDERYRVQGKDGKYTTKRFLDENKFILMPDGKMGD
                     TFFGLTAEELELRKNPAIDISSVGNIIVEQYSTADPVAKWIKAVATALPSFPYADQVF
                     MGTIN"
     gene            complement(13306..13686)
                     /locus_tag="KNP54_001129"
     CDS             complement(13306..13686)
                     /locus_tag="KNP54_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892045.1"
                     /translation="MYFKEVNFDNTPEFLASQHYINFSKTALDTDVVADENGKKYVLA
                     GSLLGESGKVVKITRGGSSGSYTYTLSEDPVGIVFSTVDVTYGPQPVASMVEGYVIIE
                     RLQGEYVKEAIETIKTKLPNIKFM"
     gene            complement(13702..14274)
                     /locus_tag="KNP54_001130"
     CDS             complement(13702..14274)
                     /locus_tag="KNP54_001130"
                     /inference="COORDINATES: protein motif:HMM:NF018515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBF0892046.1"
                     /translation="MKKGELIALGLSEEDAKKVEAESLKELENYINKIEYEKVKEELK
                     ASKEAIEGFKDGMTKEQIEELKKGYETKLTAKDEEYQKKLKEKEQKEFDMALENELIK
                     LNVHSTKAAKAELDLEKIKYENGTFTGLKEQTDTWLTQKSFLIKTGETKINYSPDNGN
                     KNTLSRAENIAKEKNEEGSKNPYADAWSIK"
     gene            complement(14320..14547)
                     /locus_tag="KNP54_001131"
     CDS             complement(14320..14547)
                     /locus_tag="KNP54_001131"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892047.1"
                     /translation="MKEYVIWFKSGNCVSGITNEDVTDKLMKDFMEADSDCRYLKGYL
                     DEDGTTVIDLSQIEAISINNCSENNIGFSKS"
     gene            complement(14598..14870)
                     /locus_tag="KNP54_001132"
     CDS             complement(14598..14870)
                     /locus_tag="KNP54_001132"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892048.1"
                     /translation="MFKKKYIKKPSKISVRNIMAFIITVVGIALGVFIGINIIMAHVL
                     GIANMVDNNTFTCVRLVYGLAGVISGYLIGKAIYLIASLISHIIYE"
     gene            complement(14889..15425)
                     /locus_tag="KNP54_001133"
     CDS             complement(14889..15425)
                     /locus_tag="KNP54_001133"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892049.1"
                     /translation="MAKFKKKSEEVEAFKWILGSPNTPIWFYQAFEKGTIWLDESLNS
                     MNRKGEVKKTICIKYKNGVIRATNGDFIIKDSEGKIYSCTFSEFEKLYENLERGHRYV
                     DEDNNKKNKLELSAKLELDTTDFEENIKSATKEIETLNEVVDRLEKKLNRIFAKENKV
                     DIDSIVKQLEERLRESIE"
     gene            complement(15427..15672)
                     /locus_tag="KNP54_001134"
     CDS             complement(15427..15672)
                     /locus_tag="KNP54_001134"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892050.1"
                     /translation="MLKLYILSIIVFCTGLYLFKMKIDSNEELIEILKNKKVRRKCNF
                     IFMALFPLLNFILGVIFIISSLLVSNEDMIKNLKGDK"
     gene            complement(15743..15991)
                     /locus_tag="KNP54_001135"
     CDS             complement(15743..15991)
                     /locus_tag="KNP54_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892051.1"
                     /translation="MDNKFKNLQHLIDSIDLGLDIEFDLYNKPYNISIGDDDTRFITL
                     CPNGDTKYYKNGKDMVDNYNIDGKLLKDLWKDIQIVNM"
     gene            complement(15993..17528)
                     /locus_tag="KNP54_001136"
     CDS             complement(15993..17528)
                     /locus_tag="KNP54_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBF0892052.1"
                     /translation="MKHNDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAINSIEKDI
                     LAWYNRFAKNEGISLLEARKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRHIYTSGYYHAAFNVQQGVNVGWS
                     LMNLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKNLV
                     NDFSKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGVTAPPFHCHCRTTTAPWFEDEEGYRAAKGEDGKTYYVPSNMKYN
                     EWYEKHIEGRLGKEKADTLRKMQLNESKDRKQFEEYKKVLGNEIPSKFDEYQHMKYND
                     TIRYEEAKKLYKDVNWQVKNQRNLTSGSVHSVPFESKPNSVFDNYKDGKLIQRRYYGN
                     TGKPRLDLDLTDHRNPKQHKIVPHKHDWLADENNHDKVKREKDMELTKAHKIANKDIL
                     KGE"
     gene            complement(17518..18912)
                     /locus_tag="KNP54_001137"
     CDS             complement(17518..18912)
                     /locus_tag="KNP54_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002603318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBF0892053.1"
                     /translation="MELDVIKKLIEQTNSKHSNFVKKADEAEKYYKNENDIIRDRSPN
                     NIGKVNTTNNPLRNADNRIPFNWFGFLVNQKISYLFTYPPTFDVGDDRVNSKITDILG
                     DRYPKEAKTLGKNASIYSKAWLHIWVDDNNNFQYANIDPRQIRAVYSSDLNRKLLAVL
                     REYKKTDDKGKEYVIYEYWTDECCYTYQNKDGNSNINGLEILNKFIEKNLDNKLETQT
                     NVYKHNFGEVPFIEFLNNDLEVRDLDNVKHLIDVYDKVYSGFVNDIEDIQEVIFVLTN
                     YGGADLTEFLKGLKEYKTIDLQSSGADDKSGLSTITINIPIEARDSLLKTTEKQIYVQ
                     GQGVDPKPENFANTSGVALKFLYTLLELKAGLMETEFRLGFAKLVRMICRHLGYSPKR
                     VLQTWTRNMIQNDLELAEICSKSVGIISEKTNLKNHPLVDNAEEEEKQIKKENSQQEY
                     DDLIPNQDGGIDET"
     gene            complement(18917..20146)
                     /locus_tag="KNP54_001138"
     CDS             complement(18917..20146)
                     /locus_tag="KNP54_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBF0892054.1"
                     /translation="MIDELYHSKQLEVLNFALNNDYFMLINYGAKRTGKTIIDNDLFL
                     LELRRVRKIANELGIKLPQYILAGADLGALQRNVLSELTNKYDIEFKFDKHNRFVLFG
                     VQVCCFGHSKTNDLGRIRGMTSFGAYINEGTVANEEVFNEIKSRCSGEGARILVDTNP
                     DQPEHWLKTNFVDKTDGKVIQSFHYKLDDNIFLSERYRANIKKSTPSGVFYDRDINGL
                     WVSADGLVYQDFNKDIHYISKDKLNDINFVRYFAGVDWGYEHFGAIVVIGEDDKGNLY
                     LLEEHSAQHKEIDYWIDKAKSIKEKYGNIKFYCDSARPEHLAAFKRNGIKAFNANKAV
                     LSGVEAVAKRIKTNTLFVVHENVNLFRKEIFMYAWNKNTGEPIKKWDDVLDALRYAIY
                     TDSLGTGIKVLTPNGRR"
     gene            complement(20139..20825)
                     /locus_tag="KNP54_001139"
     CDS             complement(20139..20825)
                     /locus_tag="KNP54_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012704107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892055.1"
                     /translation="MNEKADLAHEDYLKGLKYKEIAEKYNVSLSTVKSWATRYWKQKG
                     CNQSKKVATKKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETQDLINEIKDKDKFD
                     ILWEQITIQYAAIIRAQKIMYVKDKEEMVKELKKYESTENGEKIEYEFQFAWDRQASF
                     LNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQRARVEVLKSKINNQESKEDKLDRYF
                     DKLESVIKND"
     gene            complement(20892..21059)
                     /locus_tag="KNP54_001140"
     CDS             complement(20892..21059)
                     /locus_tag="KNP54_001140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892056.1"
                     /translation="MSDGKICVSCQRTIADVATELTIAYMENASLTPEKIAEIYKLFY
                     KNANEAFNGKF"
     gene            complement(21203..21880)
                     /locus_tag="KNP54_001141"
     CDS             complement(21203..21880)
                     /locus_tag="KNP54_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HBF0892057.1"
                     /translation="MLKILQDKNVKVMWSKNGEEVWFNANDVGEELGIVNIRDTLRNI
                     DREYKKKFNESTVGDSYTRNFKDKLPNFGTTFVTEEAVYNMSFRSNKPEAKLFTKWVT
                     QTLKQIRIHGYYIATEKDQEWLDIRAEGKKVRKDFTDEIQEFVYYATSQGSNKPQMYY
                     KHFTELVRKKLGIPKGVKRDELNQSELFDIQALERIISMKLPKLIDKDMNYKEVYKKI
                     KELIEMI"
     gene            complement(22403..22885)
                     /locus_tag="KNP54_001142"
     CDS             complement(22403..22885)
                     /locus_tag="KNP54_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892058.1"
                     /translation="MNKKTLFQEVEGRLYNYKKLESQIRIKDIYIKKLENEFCGCKAQ
                     SYEEKTGPTYNISSSVENEVIKREEDLNRLKEDKKTLEIEKETIECALTSLNSFETEF
                     FNEMYMNNEKINMDYMSNAMHIDRSHCFRIRKRIVCKIIDMLYPKIKEFELPIFSWKA
                     "
     gene            complement(22997..23722)
                     /locus_tag="KNP54_001143"
     CDS             complement(22997..23722)
                     /locus_tag="KNP54_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HBF0892059.1"
                     /translation="MNEIMTNENLRVVADDLVTVYETDTGEKIVFARELHNNLEVKRQ
                     FIDWIEDRIKQYGFKENEDYSVFHKNMKNSTGGRPSKEYVLKLDVAKELAMVQNNNKG
                     REIRRYFIRLEKLLNRTLSNSQLSQINTIVNESLLKMEVKHNIQIEQLKKECSEYYRP
                     TSKTKYDISSYIKERLGISKVNEEFELVKKRTLLALGADKWEDIPKDVLLNSLNLIDE
                     SIRIIKSERKTNQISFFEKDNFC"
     gene            complement(23737..24144)
                     /locus_tag="KNP54_001144"
     CDS             complement(23737..24144)
                     /locus_tag="KNP54_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBF0892060.1"
                     /translation="MKVFLVIDGEPVGKERPRMNSITKRTYTPNKTKNYEDLIKWLYQ
                     SKVKHYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDII"
     gene            complement(24281..24511)
                     /locus_tag="KNP54_001145"
     CDS             complement(24281..24511)
                     /locus_tag="KNP54_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBF0892061.1"
                     /translation="MIHELKILPQYFKEVVNGNKNFEVRKNDRGFKKGDLLVLQEFDG
                     EKYTGLEIRKEITYLLDNSNYLQDGYVVLGIK"
     gene            complement(24534..24803)
                     /locus_tag="KNP54_001146"
     CDS             complement(24534..24803)
                     /locus_tag="KNP54_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892062.1"
                     /translation="MITTQMYKINNEIYLNNICLEENKEITIWVEKNNTHELIWLKIA
                     NVNGKLAIFVQDIENAAIKEWQGRIAYERVISQIEDEQVEKGEID"
     gene            complement(24902..25075)
                     /locus_tag="KNP54_001147"
     CDS             complement(24902..25075)
                     /locus_tag="KNP54_001147"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892063.1"
                     /translation="MNKCEDCKYRAYEEDGEVYFYSDGSYEGGICREEYCSRGYEKKF
                     KNNGENCKSFKKL"
     gene            complement(25172..25567)
                     /locus_tag="KNP54_001148"
     CDS             complement(25172..25567)
                     /locus_tag="KNP54_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008422387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892064.1"
                     /translation="MDLPDNVIEIDILRINRNNDKKCKCKNREFIVDTVNKSVHCSEC
                     GFRVEPYDALYELAMNFERVNGQVNTLLKQRKEIASYKPHLIVFKRLESKYRGKKMLP
                     VCPICGEAFYFENLTSWINKDFYERRKNK"
     gene            complement(25570..26289)
                     /locus_tag="KNP54_001149"
     CDS             complement(25570..26289)
                     /locus_tag="KNP54_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HBF0892065.1"
                     /translation="MKYIASFSGGKDSAAMLLLILEKGLKLDDIVFIDTGLEFKEIYD
                     IIDDFEKRINFKITRIKAEKTFEEYFYTVNEKGKRKGQIWGFPYTLGAWCNSRLKLAP
                     ANKYFNKLGEHKRYIGIAYDEPSRYKRLEKNCIAPLFEEKMTESDCLKYLEEKDFYYE
                     IHHRFKRTGCYLCPKQSLESLKTLRKYYPILWQKMLKFDRDSPVPFRANGVTVNDLEK
                     RFSNEDIENERQISFFSKGVV"
     gene            complement(26294..26533)
                     /locus_tag="KNP54_001150"
     CDS             complement(26294..26533)
                     /locus_tag="KNP54_001150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892066.1"
                     /translation="MKKYKIKFEEKVTLEHEIIVEIPEEISINDICHCIENKCQRVYD
                     IADYIREFNGRQIDFTEDTCGETEMLVESFRKCKE"
     gene            complement(26629..26877)
                     /locus_tag="KNP54_001151"
     CDS             complement(26629..26877)
                     /locus_tag="KNP54_001151"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892067.1"
                     /translation="MDKLYICSSQGVEEVEILEGTKGRFKVGSNSQYLRVINKNVLDV
                     KSASYVASLNRDTAINIWNDEISKEIERLKGFLYTENI"
     gene            complement(26877..27050)
                     /locus_tag="KNP54_001152"
     CDS             complement(26877..27050)
                     /locus_tag="KNP54_001152"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892068.1"
                     /translation="MTNFEMIKSLDEDGMANFFGSTDCICEYCIYEGEPCGYICYESP
                     EGFKEWLYMEVEE"
     gene            complement(27043..27201)
                     /locus_tag="KNP54_001153"
     CDS             complement(27043..27201)
                     /locus_tag="KNP54_001153"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892069.1"
                     /translation="MDDRLEICKKMFPIITKNTRLLCHYCDGRNICSYDEEKAHELLR
                     NEEGAKND"
     gene            complement(27304..27753)
                     /locus_tag="KNP54_001154"
     CDS             complement(27304..27753)
                     /locus_tag="KNP54_001154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892070.1"
                     /translation="MSLIKYRGYDFENEKWIYSETIKWSDAVDCLFMLKENCEWQKVS
                     NVGVFSKCWSGNNEEIYEGDILKEPYNTKNKYEYGIVRQENYALELYVEWHYLKQFEG
                     KWEEITSKATIMNSKKYVVVGNECENLEEIKKEFLERKEMLENEHLG"
     gene            complement(27871..28236)
                     /locus_tag="KNP54_001155"
     CDS             complement(27871..28236)
                     /locus_tag="KNP54_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892071.1"
                     /translation="MLKVEKYFNGSVADNIFEDDLTLRNYLALYCCVHGVRKNGELVF
                     PTSEKMLIEFNVDKNRKKKKKGSKVKLINAKTGEEKIFDSIDSAACFLRLQSQAVYQT
                     IKKKTKTRSGWKAEYIKEE"
     gene            complement(28250..28507)
                     /locus_tag="KNP54_001156"
     CDS             complement(28250..28507)
                     /locus_tag="KNP54_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892072.1"
                     /translation="MIIIRSQDRLDLMRVNRVEISNKQVCAVFEEESNAREIGRYKSE
                     ERAIEVLNMIQNAVIAGTKFDIINKDGVRCNKEKVFEMPVE"
     gene            complement(28494..28904)
                     /locus_tag="KNP54_001157"
     CDS             complement(28494..28904)
                     /locus_tag="KNP54_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892073.1"
                     /translation="MELKFREWNKNGKEMYSYDEMVCYSKNLLREVYSGVYLPKNNEN
                     FEVMIYTGLKDCDGKEIYEGDIVLCRSIFFTEFAGEVKFKDGCFIAVNEMSGDCFRLS
                     ELAIVKIDGNIYEDLSKLNDIRRCDEGEIRDDNN"
     gene            complement(28979..29386)
                     /locus_tag="KNP54_001158"
     CDS             complement(28979..29386)
                     /locus_tag="KNP54_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBF0892074.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKAKPVYAIGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVLPGLDPQGFQAIDDDDIPF"
     gene            complement(29402..29575)
                     /locus_tag="KNP54_001159"
     CDS             complement(29402..29575)
                     /locus_tag="KNP54_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBF0892075.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKIAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            complement(29635..30516)
                     /locus_tag="KNP54_001160"
     CDS             complement(29635..30516)
                     /locus_tag="KNP54_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBF0892076.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLYKRSKNGRDATANILRELIENGYITRTPCRDSNTNKMLGGYDYQVYEIPL
                     ENPQKLKSRKTDFPETGFPGNRVSRKPENTEVVSNDFKVNNDITTIVINEQPQQDKTT
                     YIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAIDEAISNGVKNYKYVKTILNN
                     WIEAGVKTNLELTEYQNEFERKKKNKQEKKQSNHKNVNTPNVSKNKFHNFNETFTQYS
                     PDELDDIIKKSQKVKFK"
     gene            complement(30531..31115)
                     /locus_tag="KNP54_001161"
     CDS             complement(30531..31115)
                     /locus_tag="KNP54_001161"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBF0892077.1"
                     /translation="MEINNIYIKLMNVRVKFSKLNLKKSGENKFANFKYFELADFLPQ
                     ATGLLEEAKLCPIVTFTNEYATLTLINGENPSEQIVFTSPMRDLQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITESDTFDATSGKNEAKSNSNNRILTDKQLSRLYAIASNANVDK
                     ESLKEKVFKRFGKEIKDLTKQEYDTICNAYENKQ"
     gene            complement(31125..31634)
                     /locus_tag="KNP54_001162"
     CDS             complement(31125..31634)
                     /locus_tag="KNP54_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBF0892078.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNETEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRMQELKKIKKNALDRLKSNIKECMELLGTKKVETFL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNSIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            complement(31718..32035)
                     /locus_tag="KNP54_001163"
     CDS             complement(31718..32035)
                     /locus_tag="KNP54_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892079.1"
                     /translation="MKSLIIVRNAVEQQLNRANLEINKNEQLYTKLRKKEERNISEEI
                     ELSNALREKSVNERLKIFAESLLEIIDTQIEIKEYEENEDCKIFQLILEELERDRPID
                     VQI"
     gene            complement(32048..32275)
                     /locus_tag="KNP54_001164"
     CDS             complement(32048..32275)
                     /locus_tag="KNP54_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892080.1"
                     /translation="MKILKVKFPTKILKAGKAIRVTCARFGFESDCIITQSQEFELTV
                     VYFDKELDDLVQSSITIDDAISYDYCIEMLN"
     gene            complement(32377..32706)
                     /locus_tag="KNP54_001165"
     CDS             complement(32377..32706)
                     /locus_tag="KNP54_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892081.1"
                     /translation="MSVALQFIDTKDLVQELMRRDDTTDIIKMFLDREGIKRMELMTI
                     EEFCEYLKISDVTARNMAREAMITKDFIALKIGRKYMIDRISFEEFIMKNAMKDKDVM
                     KKRKGVI"
     gene            complement(32776..33567)
                     /locus_tag="KNP54_001166"
     CDS             complement(32776..33567)
                     /locus_tag="KNP54_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBF0892082.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDARNISNNFNNNKDRFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFTSKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EETYFKVKQHKPTCIEDVLIESLKEMKDLRLQVNQANSIALEAKTEVETIKDVVSLDS
                     NSWRTNTHQLIARIAKKQGGFEHINMLRTESYELLNKRFGVDLHRRLINKRRKMAEEG
                     VSESKREKVNNLDVIQDDKKLIEGYVAIVKDMALKYGISSDLSKN"
     gene            complement(33560..33796)
                     /locus_tag="KNP54_001167"
     CDS             complement(33560..33796)
                     /locus_tag="KNP54_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892083.1"
                     /translation="MNKLKDFRIQKGLSRNQLGAELGLTSRYIAFLENGERVPSLNTA
                     VKIAAYFNTSIEYIFLKNNCTKSTFKEKGAEKYE"
     gene            33941..34306
                     /locus_tag="KNP54_001168"
     CDS             33941..34306
                     /locus_tag="KNP54_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892084.1"
                     /translation="MIGYRIKELRKEKDITQKELATFLGLTPKMISFYEKEERFPPHD
                     IILKLSDFFNVSTDYLLGKVNVKNIDNLSELELIENLNFSDDIKEALKLISELSPSSQ
                     EKMFKIAKVFLEEELNEKK"
     gene            complement(34321..34461)
                     /locus_tag="KNP54_001169"
     CDS             complement(34321..34461)
                     /locus_tag="KNP54_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892085.1"
                     /translation="MEKSKKLLIDTGDTLNKLRENNSEKLEKYIELLKEYYKQENKKE
                     RE"
     gene            34958..36406
                     /locus_tag="KNP54_001170"
     CDS             34958..36406
                     /locus_tag="KNP54_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HBF0892086.1"
                     /translation="MSILNLFRKNKNKNNVDCNEKSNESKQSYNDSTTLSLECNSNSP
                     HNIEVKNEINKVLNVSCNDTTNLYELEKQAREKSDALYDIHTNSINKFNPQNNILETD
                     TKPLTSIEKSFLKYIIGENIYEPYIATYWTYEYNINYSYLISKFFNMDYLKISNYIED
                     LTKLTVSELKEILKSNNIKSTGKKAELIERIEKEISCKDLSNFFNSSNKYYALTDKGK
                     ELLKDVRKSVTKNTDLEDQCLELIYIDKYEEAYDLICKYESSKNIQRGININWENHKI
                     TPMKIESYKAIKELDINLKDTLLDNIIKSSYILCDMLGNNSKTSILVKRLVGEKIDNI
                     EINNAINSINDVIYNHSTITYNANDSINNKNLHYMDIVKNNKSIPFEVNNKNYNFKIN
                     ENEIYFFNILKIKMYENELKNNFVFDRMSDGAFNVFDTSDNFIGKVKLQGRKKWIMYT
                     KNEFGSEHIYGELIHLIDGIDAWIKYSKEYLK"
     gene            36677..38341
                     /locus_tag="KNP54_001171"
     CDS             36677..38341
                     /locus_tag="KNP54_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBF0892087.1"
                     /translation="MNNENEQLKSDLLINDEKIKNLNFKIPWYYSLWTISILILSTFS
                     TYSISFIVAIIFLFKRNKIMKKHKDSISILLSDVEKINNKYILLNDEIKMKEKHFEDL
                     CESNENKLKELSNLLDKKKVEIDKFDSENQDKFKLIEELKIEKERLDNLIKDKNILKD
                     NINTLNSHLEELKNEREELRDINTTLKNKKEELKRLSEELIQTEDEVLLQSFGLYNPK
                     YDFENSDEYMEKLKEIREMQKLLIRNKTGVKYSDSWTVDGSVQKGRTMTNQNIKTALK
                     LFNSECDIAMSKVSFKNIDSIEKRIRKAFTDTNKLNTSNKVSIKENYLNLKIDELYLY
                     YEYLQMKEEEKEEQRALREQMKEEALVQKEIENQKRKLKKEELQFKNELLRLKSTIPE
                     DENDKLEWEQKINSIEEKLALLSKDLDDVLNREQNTRAGHVYIISNIGSFGENIYKIG
                     VTRRLDPTERINELSSASVPFKYDIHATIFSEDAPKLESALHKAFDNKRVNKVNNRKE
                     FFKVTLDEIRTEVEKNFDKTVEYTKLAEAQEYRQTLKIQELNNKLA"
     gene            38855..39973
                     /locus_tag="KNP54_001172"
     CDS             38855..39973
                     /locus_tag="KNP54_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBF0892088.1"
                     /translation="MNIKSAFIRKRGEKFHVYVEYIEETTGKIKQKSYGSYEKKKDAE
                     KHLIEIKSTINNNKFITPNKTTLVERCYKYIMTNEKNWSPYTVINRKSWVKNYIEPFF
                     KDTILIDVNPSLLQIFIDKNFDGSAPSTAKVRYNFLSSVLKEAYRLKEISENPCDFVK
                     LPAQNVTYEIEIYNREETLLLIEKLKDSLIEIPILLMLLLGLRIGEVAGLRWSDVNLD
                     NSIININQILIYANSKITFKEPKTAKSKRALSVPKELVEKLKIEKLKQNKMKLQGTLI
                     NENNLVCLNTNFNAWIPTALSKTFHNFIKRNNLRNIRVHDLRHTNASLLLLGGTNMKV
                     VSERLGHTDIKITMNRYSHVLEEMDKEASDNLSKLLFK"
     gene            complement(40124..40804)
                     /locus_tag="KNP54_001173"
     CDS             complement(40124..40804)
                     /locus_tag="KNP54_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892089.1"
                     /translation="MQTKILIIDGDKDNCKKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(40854..42869)
                     /locus_tag="KNP54_001174"
     CDS             complement(40854..42869)
                     /locus_tag="KNP54_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBF0892090.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLYFL"
     gene            complement(42941..43618)
                     /locus_tag="KNP54_001175"
     CDS             complement(42941..43618)
                     /locus_tag="KNP54_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892091.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(44198..44281)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(44514..45356)
                     /locus_tag="KNP54_001176"
     CDS             complement(44514..45356)
                     /locus_tag="KNP54_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0892092.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(45608..47392)
                     /gene="pepF"
                     /locus_tag="KNP54_001177"
     CDS             complement(45608..47392)
                     /gene="pepF"
                     /locus_tag="KNP54_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBF0892093.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYAKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(47458..48123)
                     /locus_tag="KNP54_001178"
     CDS             complement(47458..48123)
                     /locus_tag="KNP54_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBF0892094.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(48274..48435)
                     /locus_tag="KNP54_001179"
     CDS             complement(48274..48435)
                     /locus_tag="KNP54_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBF0892095.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(48513..49022)
                     /locus_tag="KNP54_001180"
     CDS             complement(48513..49022)
                     /locus_tag="KNP54_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBF0892096.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            49228..49446
                     /locus_tag="KNP54_001181"
     CDS             49228..49446
                     /locus_tag="KNP54_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBF0892097.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            49464..51410
                     /gene="feoB"
                     /locus_tag="KNP54_001182"
     CDS             49464..51410
                     /gene="feoB"
                     /locus_tag="KNP54_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBF0892098.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(51589..52644)
                     /locus_tag="KNP54_001183"
     CDS             complement(51589..52644)
                     /locus_tag="KNP54_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBF0892099.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(52692..53492)
                     /locus_tag="KNP54_001184"
     CDS             complement(52692..53492)
                     /locus_tag="KNP54_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBF0892100.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(53485..54276)
                     /locus_tag="KNP54_001185"
     CDS             complement(53485..54276)
                     /locus_tag="KNP54_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0892101.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(54316..54738)
                     /locus_tag="KNP54_001186"
     CDS             complement(54316..54738)
                     /locus_tag="KNP54_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBF0892102.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(54754..55233)
                     /locus_tag="KNP54_001187"
     CDS             complement(54754..55233)
                     /locus_tag="KNP54_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0892103.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(55365..58121)
                     /locus_tag="KNP54_001188"
     CDS             complement(55365..58121)
                     /locus_tag="KNP54_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0892104.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDIIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT        18487 a        10393 c         6270 g        23163 t
ORIGIN      
        1 atagttaact cataattacc ttctccaact atactatcta gccaattcct taaaaatctc
       61 tctgagtaag gtaatttact tatatattta ctaaaaatcc taaaccttct atcttctaaa
      121 ctctcattac ttttaggagt tatagacatt atcttttccc atctttttat accacttata
      181 gttaggtcct ctaaaaactg gtcatttgat aggtccttta atttatcatg taatattttt
      241 atttctttat ttcctacatt aaatactttt atatattctt ctttatcttg tagaatttgt
      301 ggtaagtaat ttattagatt aatctcttta tccaactacc tcacctctca ctactatact
      361 gttactattt attgttagat tagatttaac ctcatttatc attgtatttg caatgtctaa
      421 tactccatca atactaagta atctagtttc aatttgagat atacggacta ttaagttttc
      481 ttcatcttcc caactcatgt taagttcatt taaatagtcg tctattgctt cttctgcaat
      541 tgattttata ttctcccaag tgtagccatt tttgtatgtt atctctgctg atatatttat
      601 agttgtactt acaacacctg taacagtaac tttatgccct attggtgcta atcctaagcc
      661 ttgtccttga tgtccaattg ggtcaatttc ttcttgcact aaattaacta aatcctctga
      721 tggtactttg aaattagagt taattattac taacttaaca gttcctccac cgtcccacac
      781 aggataaacc ttaactcctc caacatcttg tattttgtta acttcatctt tataattttg
      841 catatttcca ccaaagctct gtgaatttag gctatcataa tatctttgtc ttaaactatc
      901 ctcactctct tcatcctctc catttatcaa gatttcagtt agttcagcag tttcaagacc
      961 atctatatat tcaataggta ttagttttcc taactcaaat ataggtccag cagtttcaca
     1021 tttcatttta tatgtttttt cagatattct ctcaattgca atataattgt attctcctag
     1081 attaaaccta gaatcaagtg gaatatctat attaaacact ccttttgcaa tggtattagt
     1141 tgcagatagt ggtgtaattc ctcgttcttt acatcttttc tccaagtaat aataactagc
     1201 agtatctacg aatgtttggt ctagtaattc atccatagca atgtatgttt ctgtaagttc
     1261 tatagcaaca ggagcaagag cattatatat tatagaacct tcccttttat caaaagtatc
     1321 tggtacacta tctaacattc ttttaattat attttcaaat gtcattaact caaacaatta
     1381 tacactcacc accttctctg cttttatatt tccatattta ctgtgaactg tgaacttaca
     1441 atgtactttt ccttttacat tttgaaattc aaaattatct acattttcaa ccctatcatc
     1501 ttgaattagt gcttctttga ttcgtctttc aagttcgggg attacaaagg atataggttc
     1561 tccaataagg tcgttcaact cgactccata attccaagaa taaatgaggt gctcatacct
     1621 ttcagtattt aaaattaaaa agatggtctg ttttaatgct tcaacatcat cacaaatacc
     1681 atctatctta gatttttcta tatttaattt aaaggtctta cttggttctt gccttacatc
     1741 aaaattaatt attgatacat cttcaatgtc ataatccaaa ttatcgcttg gtaacacctc
     1801 atcacatcct atctaaaatc aaatattgct gtcctccttg catcctaatt aagactaatt
     1861 tatcccctat ttttttatct gtatatcttt taaaagtctc tgtttgtatt agaaaaaatt
     1921 cttcaaaaga tgctttttgt tctatcttaa ctatcaaagg attaacactt tctatagttc
     1981 caaatgcaat ttgcattgga ttgcttgttt ctactgcatc cattgcagcc ttcttaatta
     2041 tttgcaataa ttcttgtgac actttatcac ctcacttaaa agaatcttct agctcttgca
     2101 aaatcatgct ttttcttttg tctaccactt aaactactta tttttactac gtcaccagtt
     2161 tgtggagcat gaatatattg gtcatttcct atatatagtc caacatgatg tacatttcct
     2221 tttcctttgt tgtatgcaaa gaatactaaa tcaccagctt ttacatcatt tatgttacat
     2281 aatagttttc ctctactatc ttttgattgg tctgctgaaa ctcttttgag atttattcct
     2341 gcacctcttt taaatgccca caccataaga ccactacagt caaaactctt tggaccatta
     2401 ccaccccatt tgtaaggctt gccaagttga ttttttgctt cttgaataac tttacttact
     2461 ttattattat tgtttgttga tgtattagaa ttattgtttt gaacttgata agttaaatct
     2521 tttaaattct tttctgcttc ttcattactt ccaactcctg tgcctgcact attagaatta
     2581 taagtacttc ctgttatttg cttataaaat gcacctacac attttaccca ttctttgtct
     2641 gaactagaag aatatttatt tctgatgctt tctaaagttt ttcgtcctat atggatatag
     2701 tttcttgata aattacttat acctcttttt attccttcgt ctacactaga aaaactcatg
     2761 taatctccat tttttttcat tccaaagaaa ttatttttag tatttgcaat atttgaagtc
     2821 cctctagctg attcgtgcat agatatagca gccatgagtg ctggattaac tttataagca
     2881 tttgaatatt taacaaatat atttcctgta tttgataatt tacctttaag tagtttatta
     2941 atcttattag ccatatcagt atcttcttta cttgtagtac tttgtgcagg accattttgt
     3001 ttctcatttt tattattagt atttccacta ctataacttg atgaagaata agaagcaaat
     3061 tcgtctccat caaccaaagt taggtccata aaatgactgt tattttcaaa tgtatgtttt
     3121 actttctcaa ctaacatata attttgtaaa tcaatatctc ctaacgacaa aaaaacaggt
     3181 actaaacaac ctgctcttac tctaatatct cctaacacat tttttaaact taatgactta
     3241 gttttcttat tatatagttt taggagtata tcacattttt gttttatctc tgcttcactc
     3301 atatttttat caactgtatc aaatagttgt agtattcccc aactcctcat atgcgttgag
     3361 tcttgagcaa tatacacatc tctttttcct gtttcttcat tatctcttac aagtttgatt
     3421 tttgtataag tatcactatc aatagaagaa ttatagtcaa agtcctcgat tacatcatta
     3481 ttcataacag tatcaagttt cattgatgca acatttttta gtgttattct tccaaagtca
     3541 tcatacaagg taaacatttc ttttttttct cttaaagtat catctagtgc agttaaaatc
     3601 atatcaaata aagttttgtt ttcttctatt ctagatattt tatattttgt atcttctatg
     3661 acattgtatt ttaaattaaa atctttagcg agcattttta taagttcgct tgctgtttta
     3721 ttactatata cataagtatc tttattttta aaatatctta actggtcata tgcaataatt
     3781 ttgatgtgat tttctttatc tcttttcttc tgaaatatat atccatagaa tatgcctaca
     3841 cccttgtaat ataatctcac tgaattacct tcacaaaact gtagtatatc atccatgact
     3901 atagtaaact ctaacttaga aggtgttcct cgtctttcta tttcccatgt gataccatca
     3961 atgacagcag gttcgtagaa atcttcccaa tgtgcaataa ctaaccttac atctctatca
     4021 tttgctaaca ctaattcatc aaccaagttt taacacctgc cctttgtaaa tagtgtattt
     4081 acttaagttt ttgcccttat ttgccttatc catcatagat ttatttagtt cgtatacttt
     4141 cttatataat gaaccattac caagttgttt ctgacaaatt gaccaaaggc tatcccctgc
     4201 ttttactgta tatgttttag ttttagtgtt tgtggcattg actgaatcaa ctcgttttgg
     4261 ctctatcttt acgcttggtc taccagtctc atttttagga ggggcaagaa ctaacttttt
     4321 agttgagtaa tctctatatt gctttaactt tattgcaact tttgtatctg aaccattttc
     4381 tgcatcttct gaaatagcat actcttcaag agatactttt atattagtgt taaatagtac
     4441 tttattacct aattccctcg atacaataaa ttggaatggc ttacaatctg tttttaatag
     4501 ttctaattta cttaaaaaga attgaacatc tttaaaagct ccacgataaa aaggtaattt
     4561 attatgtgta aattctgctt caaaacttat ctcggataac ccttcttttt ttagtatgtt
     4621 tacttctcca gtatttatca aatcaactgt tttattttta tttgttattt ttatttctaa
     4681 tttgccaggt gcgattggta attgtactcc atctaaataa aagtcataag ccatttatat
     4741 ccctcctttc taaactactc cctcagcaga tacaaccata gcgtcattta atttttctgt
     4801 tagtacatta actattccat ctaagtcggc atctttattt atgttatttg tgttgttcat
     4861 gtcaatttta atgttgactc ctgtaaaacg gtttattgtt tcctgttctg caatatctct
     4921 aagatatttt aagtcttctt gacttttatc cattgtttta gccattttag ctgtatttcc
     4981 tgcggtatct tttgctcctt ttgctgcatc gcccaaaggt gagtttaatc ctgctgagcc
     5041 tattccatca cctaatccat atttatcatc ccacaaatcg tcaagaccta aatctttttt
     5101 tgccttatca gctattttac taatatcaaa agtatccttt attttatttt ctaagttttg
     5161 accaaaggca tatccatttt tagcccaatc tccaacattg ttatactcta attgtttaaa
     5221 ggatttataa ccttttggct ctgctccaag ccatttattt aagtctcctt tagctttttg
     5281 caatgtactt gtaatagact ttgtatgacc aaccatatca gcttttccaa gtcctaactt
     5341 atctccaagt cctccaaatt tatttaagac atctacaaat ttattccaag cttttaatgc
     5401 cccattaatt ccatctataa tagagtttgc taaattagta gcaaattcat cacatccttt
     5461 tgtcatagat ataagattat ttaatactgc tgtggctaaa ttaaaaaata atttctttac
     5521 tgaataaact ggatggtcta atacatttgt aaaaaactca gcaaatgata taaaaacatt
     5581 aatccagaaa aatacactat ttataataaa tgctgttaaa cccgataatg ctcctgcaac
     5641 aattccaatt gctgaataag atgttcctgc gaatttattt attacagcta tagctacaaa
     5701 aaaggcaaca actatggcta taattccata taaaatccaa gtgatagggc aagctgccat
     5761 tgctgcgttc aatccgtcct gtgcaattgt gcttgctact aatgctgctg ctctataaga
     5821 ctctgctatt atatgagcaa aattcatcgc taaagtttta gcagataacg caatatcttt
     5881 tactttatta gctatactaa gtaatagtgc attgttatat actaacatag cagctgcaac
     5941 tccaagtact attggtgcaa taatactcca gttctgagca aatacattag taatatttaa
     6001 tgcttgtgtt attacccagc caagcacttg cactatcaga ctaacaccta caataatagc
     6061 atttacaaat gcttgaaaaa atggacttcc taatatattt ataattccat taaaaatact
     6121 aaatgcaact gctcctaaaa catataacga atctataaaa ttatctataa aggttcgaaa
     6181 acccctacta gacatagctt gttctatttt tttctgtata acaccaaata tcatgattgc
     6241 attattttta attgaagtcc aaatttgaga aaatgtgtaa ggcatttttt caaactctga
     6301 attggtctgc tctgctgctg caagtaatga gttttttaca atatctgctg ttaacattcc
     6361 ttcacttgcc atacctctta tcttccctat atcgacctcg agatagtcgg caatagactg
     6421 aataatatta ggtgctgact caaacacagc atttagttcc tcgcctctta acacaccact
     6481 tcctaaacct tgtgtaagtt gtaaaagtgc tgaattagtt tcttctgttg ttgctcctgc
     6541 aattacaaat ttcttgttaa gttgttccgc gaatgctact atttcttttg tactactaaa
     6601 tgctttgcct gcattcatgc ccactctgct tacaattttt gcagtatcta aataagatgc
     6661 tcttgctctt tccgctgatt gaaatatcat tttgttgagt cctccatcag attgttgccc
     6721 gtcatttatc atagctagtc tcgcattagt actcgtcatt tggtcactta aattaatcaa
     6781 accaccaaca cttctcaatc caatataagt tgctactaat cttttagcat tttctactaa
     6841 cttatctgta ctacttgctc cttttctaac atcatcatta aatctttttt gttgttcatc
     6901 agcttctctt atttgttgtt ctaatctatc aaatccagct tctgcccttg ctaactcttc
     6961 tctagctgtt ctaatactat tagcatctat agcattgcta gatgttcttt gtaattgctc
     7021 gaatgaactt aatacaatat tcatagcatt agtcatgtgt ctaaaagcag gtgtcattcc
     7081 gtcgaaaatt cggatagatg tttgtatagt tgccattttt ctgctctcct ttctgttaat
     7141 ttagataata aaaacactta ctaatttagt aagtgttttt attatgaata catctatttt
     7201 ttgcctgccc aaaattgctt gccacagttc aaacatgtta ctctaacttt ctttgctcct
     7261 aaatttccag ctactaaacc tattccacca gttaaactcg ctcctactac tgcttttcct
     7321 ataccaaaac cctttttttg agctgtcaag gatgttgaac cacacttagg acaacaagca
     7381 actgattctt gttgagcttt ttcaatatta ttttttctat tttgattgtt tgttattttt
     7441 tccttttctg aattactcat agtatcatca ataaagttgt tttttaactc ttcaaaggaa
     7501 gaatccacta ttttttttgc ttcctttata ttcaaaccgc ttatttccat tacatttttt
     7561 attgcattta ctttttcttt tctatatttt ctataaatct cagtcatatt tacttctatt
     7621 ccattagcat caatgattaa atcatttgat ttaatattat tatcttcaat aatctcattt
     7681 tctacagcag ccccacaatt cgaacaaaac ttgcctatac ctgtgatttc tgcaccacaa
     7741 tttgagcaaa acataataat tcccccctgt acaatatttt tataaatatt atactatatc
     7801 cataaaaatt tttacattat agtttgactc caaaacccat tttaagacct gtaattttag
     7861 ataatttctt aaatgtggtg cagtgataaa tatctacaac atggattatc ttctcttttt
     7921 atcacttcat catttttttg aacatataca ctttaatatg tctagtgata caatataaat
     7981 ctttttctgt aagttctata tctttattca tttaatccct gcctaccttc tccttcctct
     8041 ctttttctct ctttcagatt ctttcattgc ttcctcttca tcctctatct taacaagtat
     8101 tgaggcggct gctaatgctc tctcattaac ttctaaattc atatattcac taggtttcca
     8161 ctttaatttt tggatacaat aatgagtgat gctagcatca aaatcaccgc ccctaattag
     8221 ttttttgctt cttctacttt atcttcaaat gttgtatcaa atccattaac ttcgttaact
     8281 tttactgtat aatttacata ctcacctgct gtaagcattg tttttaataa ctgagcttct
     8341 cccatcactc cataactatt ttggagttcg gcatccttta aatctggaaa tactgtagat
     8401 gctacacata actctgctac ataactattg tagtcaattt cacttgtgaa ttgacctgtt
     8461 ggcttcccat tattgccaat cactttcact cttttggtac agtttcttct taatacttca
     8521 tcttcctcag aagataaaac tcttaattcc cattcaactg gctttcctcc ttcgtctaaa
     8581 aatctatcgc ttgccacata cattacattc tcatttttta ttgcattttg acttaaaaaa
     8641 gcacttaaat tactcatttc ttaattctcc ttttatttta atttttacat aaaaaacaca
     8701 catctataat ttataaatgt gtattctata tcatacctaa taaaatttta aattcttctg
     8761 gcatatccca atcatcaaaa gtaaaatcta tatcctcatc taaatattca ctatctgcat
     8821 caaatttagc taatgtaacc tcatccatat tgcaatcttt taatataata gtttgacgac
     8881 ctactgaact tgttgggtct tcattagtaa tttgcatatc gaaatatata tcttctccag
     8941 tttccttata tctaagcata agttttctaa agatagaagt attataatga acagttgcac
     9001 ttcctgtgcc ttcccatcca gtagttttgt ttccttttcc tgtttgccct aaaattggta
     9061 tcttactttt attcttctta aatttagcct ctaccttgat acactgcata agaaggtatc
     9121 ttttaccttc aatggtaaca tagcattctg ccaaagatgc acttattgca tcttttgact
     9181 tcatagtaat atttttagcc attctaatat tctccttcct aattaactaa ctgaaacagt
     9241 catataaagc ttactcatag catttataac cttaaccgca tcactcacta taactgtttt
     9301 cttgtcattt ccaagctcca cactaacatc atcagtttta aaatcttcta ttgcccttat
     9361 attctctaat tctttatggt gtttaacaac atcattccag aaacttattc ttcctgcctt
     9421 atcattcgga actttaccta aatacttttc attaaataaa gttgcaatat cattagcaat
     9481 ttggtcaagt actctaacac tttggttact tgaaaaatcg tcatttttat catctgtaaa
     9541 tgatacaaaa gtatttatgt cctctaacac atgaacttca tcaccaactt tatgaaatat
     9601 aaatttacca ctctttagtg cttcttcaag ttgtatttgt gtgtaattta catcaacatc
     9661 aaactcacca tcatactttt tattagtatt agatttattt atatcgcatc ctgctatagc
     9721 tccagtagtc caataaacta aactagattc taataaccca gtatctttaa ctttattttc
     9781 tacagatact acaccttcgt aatctgcatc attcttttta tatagtacag tttgaaactt
     9841 agctcctact ttatctctca ttcttttagt aaactctaca aataaacttt taatttctgc
     9901 tgttgtagcc aaactgccta gtgcattaaa tgagtagctt tctattttat ccaagaaagc
     9961 ttgatactct gctcctgtga ctgattcgcc attagttcca ccagtaaata caagccctgc
    10021 acttgcttct agtgttgtat ccttcttcca agtaatatag tcattgtcct gtaagtctgt
    10081 aataactttt gctatttggg tatctacttt cttattatcc aaaagtgtta caacatcaaa
    10141 cttagtgtta tcatcaatgt ttgttgtaac tataactttt aaatcattac ctctagtacc
    10201 tgagtactta gctgtagcaa tactgcaact agctttaaca cctttattca atttataaaa
    10261 atatcccaac cttatatttt tgaataaatc tctcaaacct ttcagcttct catgagtata
    10321 atcatatcca aaatacttag ttgaatactt ctcaaaatca tcactggtta ctgtgaaaat
    10381 ttcttcatct atgccccaat ctaactctaa aggcattgca acaatacctc tatccgataa
    10441 tgaactggtt gcccttgtag cacttacaaa atttatatat gcaccaggta ggaccttatt
    10501 ttgtgttaca aatgttcctc cacctaaagc catctaactc actcctttca taaaattatt
    10561 tattatttcc tctacttctg agaaggaata taactcattt tcttttaaaa ttgcatttaa
    10621 taagtctttt ctatttacat acttcttaga attaactatt tgctccttag taaacttgta
    10681 gtcatcttct ttgcttaatg ttttattcaa aattatcacc tctcttcaaa ccaccaaata
    10741 attcaacatc attcattttt tctgtatcat tactttttat agtgaagtag ttataatcaa
    10801 cgaagaaatg aagaacatta tctataattt caaaattcat atttgtgcct ctaactaaat
    10861 ctccatcaat ttctatatac tctaattcct caagtagcat ctcagctacc tcatttattt
    10921 caaaactctt atcttttgaa cgaggaaaat aatgtacatc aaaagagttc ttttttaatg
    10981 tcctgccact tggatatgat actttgcttg gatttaaagg aacaataaaa aaacaaggtt
    11041 catttatacc ttgctccaca tcttcactat aaattgtata ttcatttcca aatgatttat
    11101 ctaatttaat agatattcca tcaattatat tattaagcat caaatactcc tttcaacaag
    11161 attaataact ttctctctat aatcttatca acttgacttt gtagttccat ctctgaaatt
    11221 gttaagaaat gttgtccttt aacccatccc ttaccatctt tagttctatg cccgaaattt
    11281 acataacttg catattcagt cggattaaca acttctataa tataattatt tccttgttta
    11341 tacacaggaa gcgacctagc ataagccact ccattccatc cttgtcgtaa gaatcctgta
    11401 tcaactggtg ttcttctaat tactttccca agtaatcgtg ctgctaattc tcttgctgca
    11461 tccttgcaaa acttatctaa atcaatcttt gtaagcttct ccatcttttt acaaactctt
    11521 ttaaactctc taaaatcaac actgccccat ctagccatta tgctttatcc ttaaataact
    11581 caagtattat ttcttgatga tttggatata tagctgattc tccacttctt acatactctc
    11641 ttgttatgtt attttgagta gttataataa gctttgaacc tgctttaacg cttatgtttg
    11701 gagatataaa gagtttgatg gtttgtgcaa gtttagctac ttttccttct tctgtagaat
    11761 taatgttttt atatgaaagc ttacaaggtt gattttctaa tacaatcact tctttattgt
    11821 tagttcgttt tgtcacaggg tctttgactg gctgatactc aattatagta catttatctc
    11881 tgtataacat ttctattgct tttctagtct tatccatcat tatttccacc taatttttct
    11941 gtatctgttt aattgtgact tataatcttt gagtaacgat tccttaaatt cactagctga
    12001 acttctgtat gaaactgatg tatcaccttc tgatatagaa gaaatagaac ctagtgcaat
    12061 atcttcactt cctagattct catttttata catatctata gccatcctta aaacagtact
    12121 atttagccct tcgggaataa cagatacatt acaataattt ttaactattt cctccacatc
    12181 ttctaatata aactctaata tcatctcttt tgaataatct tccttactga ttcctaaaag
    12241 tttttttagt ctttcaactt ccatatcaac acctctaatt tattgtaccc ataaacactt
    12301 ggtcagcata aggaaaacta ggtaatgctg ttgcaactgc ttttatccac ttagcaactg
    12361 ggtcagcagt agagtattgt tctacaatta tatttccaac tgaactaata tctattgctg
    12421 ggttttttct aagttctaat tcctctgctg ttagcccaaa gaaagtatct cccatcttgc
    12481 cgtcaggcat aagaataaac ttattttcat ctaagaatct ctttgttgtg tacttaccat
    12541 ccttgccttg tactctgtat ctttcatcat aagtaaaaat aggaggaaga gattgagaaa
    12601 ctaaaaatgt atttaattca tttaaagtaa gtagtttatc actatttaca ccaaatatag
    12661 cttttcttag tttttcatct cttaagatta tatttaaaat agttttagaa gttaatgacc
    12721 ttgttggagt aaatccagta tcaacaacta ttttatcagt catattataa atatctccta
    12781 atatatctgg tgttccacta gaccaagttt ttgtttcttt atgatttgtt ggagttccat
    12841 attttaaaga agctttaact ccattttcat ttatattaag ttctccagtt gataaaactt
    12901 ccattctcat tgcttctatt ctagtattta cacttgatac aaggttatca acatcattaa
    12961 atatttgatt tatcatttga gtttcttctt gtgagtttct tggctcttca agtacaatta
    13021 tatctttttc atctagttta atttttcttt tcacaagtgc aagttcagca atacttaaat
    13081 tagcaccttc tcttgatgca atctctgctt ctgtatcaaa agcatgaaca cttgctgata
    13141 ctggaagatt agatgcacct tttatcatct ttatttcaag tccttctatc ttttgagttg
    13201 gaaataataa atctcccatt gtttctttta attttctagt ctttgtatag tttatcagct
    13261 cttgaactga caataattct tctactcttg ccatatttca tcctcctaca taaatttaat
    13321 atttggtaat tttgtcttta tagtttctat agcttctttt acatactcac cttgcaatct
    13381 ttcgattatt acatagcctt ccaccattga tgcaactggt tgtggtccat aagtaacatc
    13441 tacagttgaa aaaactattc ctacagggtc ttctgataat gtgtatgtat aactacccga
    13501 agaacctcct ctggttatct ttaccacttt gccactctca cctaataaac tacctgctaa
    13561 cacatatttc tttccatttt catcagccac tacatctgta tctaatgctg tttttgaaaa
    13621 gttaatatag tgttgagaag ctagaaactc gggtgtgtta tcaaaattta cctctttaaa
    13681 atacatactt tatcctcctt tttattttat actccatgcg tcagcatatg gatttttaga
    13741 accttcctca ttcttttctt tagcaatatt ttcagctcta cttaatgtat ttttattgcc
    13801 attatcgggg ctgtaattta tcttagtctc tcctgttttt attaagaaag atttttgagt
    13861 taaccaagta tcagtctgtt cctttagtcc tgtaaaagta ccattttcat attttatttt
    13921 ttctaaatca agttctgctt ttgctgcttt agtgctatga acattaagtt taataagttc
    13981 attttctaac gccatatcaa actctttttg ttctttttcc tttaatttct tttgatattc
    14041 ttcatctttt gcagttaatt tagtctcata gcctttttta agctcttcaa tctgctcttt
    14101 tgtcattcca tccttaaaac cttcaattgc ttctttagag gcttttagtt cctcttttac
    14161 cttttcatac tcaattttat taatataatt ttctaattct tttaatgatt cagcttctac
    14221 tttctttgca tcttcttcac taagacctag tgcaattagt tcaccttttt tcattttatt
    14281 taattctcct ttcattttta gaaaataaaa aagcccttgt taggacttac taaaaccaat
    14341 attattctca ctacaattat ttattgatat agcttctatt tgtgataaat ctattacagt
    14401 tgttccatct tcatctaaat accctttcaa atacctacaa tctgagtcag cttccataaa
    14461 atctttcatt aacttatcag taacatcttc gtttgttatt ccagatacac aatttccact
    14521 cttaaaccaa attacatact ctttcaataa tacaaccctc ctttcatttc ttacaaaata
    14581 aaaaatcttt gaacaaatta ttcataaata atatggctta ttagcgaagc tataaggtat
    14641 attgcttttc ctatcaaata cccacttata actcctgcta agccataaac taatctaaca
    14701 catgtaaaag tattattatc taccatgtta gctataccta aaacatgagc catgattatg
    14761 ttgataccta taaaaacacc taaagctata ccaacaactg taataataaa tgccataata
    14821 tttctaacac ttattttgct tggcttttta atatatttct ttttaaacat atttccatcc
    14881 ctcaaaactt attcaatact ttctcttaga cgttcctcta attgttttac aatactatct
    14941 atatcaactt tattttcttt tgcaaatatt ctatttaatt ttttctctaa tctatctact
    15001 acttcattga gtgtttcaat ttcttttgta gcacttttta tattttcctc aaaatcagtt
    15061 gtatctagtt ccaatttagc tgaaagttct aatttatttt tcttgttgtt atcttcatca
    15121 acatatctat gtcctctttc taaattttca tataacttct caaattcact aaatgtacat
    15181 gaataaatct tgccttcact atcttttata ataaaatctc cattagttgc cctaataact
    15241 ccatttttat attttataca gatagttttc tttacttcac ctttacgatt catagagttt
    15301 aaagattcat caagccatat agttcccttc tcaaaagctt gataaaacca tataggagta
    15361 ttaggacttc ctaatatcca tttaaaagct tctacttcct ctgatttctt tttaaattta
    15421 gccatattat ttatccccct ttaaattttt aatcatatct tcattgctaa ctagtaaaga
    15481 agatatgata aatatcacac ctaaaataaa attaagtagt ggaaataaag ccataaaaat
    15541 aaaattacac tttcttctca cttttttatt tttaagaatc tcaatcaatt cctcattact
    15601 atcaatcttc attttaaata aataaagccc tgtacaaaac acaattattg ataaaatata
    15661 taatttaagc atttcaaatc accctctcaa taaattttta cataataaaa gcacctacta
    15721 atttataact tagcaagtgc ttttacatat ttactatttg tatatctttc cataaatcct
    15781 ttagtaattt accatcaatg ttgtaattat caaccatatc cttaccattt ttataatact
    15841 ttgtatctcc attagggcaa agagtaataa accttgtatc atcatctcca atagatatat
    15901 tatatggttt attatataag tcaaattcta tatctaatcc taaatcaata gaatcaatta
    15961 aatgttgtaa attcttaaat ttattatcca ttttactctc ctttcaaaat atctttgttt
    16021 gctattttat gagcttttgt aagctccata tccttctctc tttttacctt atcatggtta
    16081 ttttcatcag ctaaccaatc atgtttatga ggtacaattt tatgttgctt tgggtttcta
    16141 tggtcagtta agtctaaatc taatctaggt tttcctgtat taccatagta tcttctttga
    16201 attaatttac catctttgta attatcaaat acactatttg gttttgattc aaatggcact
    16261 gaatgaacac ttccactagt taaatttctc tgattcttaa cttgccaatt tacatcctta
    16321 taaagctttt tagcttcctc ataccttata gtatcattat acttcatatg ttgatattca
    16381 tcaaatttag aaggtatttc atttcctaat acctttttat attcttcaaa ttgttttcta
    16441 tctttactct catttagttg catttttcta agagtatcag ctttttcttt tccaagtcta
    16501 ccctctatat gtttctcata ccactcatta tacttcatat tagatggtac ataatatgtt
    16561 tttccatctt ctccttttgc tgctctgtaa ccttcttcat cttcaaacca aggagctgtt
    16621 gttgtcctac aatgacaatg aaatggtgga gctgtaactc caacttgata atccttcata
    16681 tcaaatactt ttccatctaa ctctctacat atatttgatg tttttaagtc tagtgtggca
    16741 ataatctcat acttctctac atctaaatca ttgaaacaat cttttcttga agctgatgca
    16801 aagaaagctg attcagtcat tatcaaattc ttagcttgtg atttagatac attaaatctc
    16861 ttagaaaagt catttactag gttctttgga ttttcacctc taataattga ttgagttagc
    16921 ttagtatgta actcattaat taaagcaggt ctatgtttgc cccaaatcct ttcactaaaa
    16981 tttaatccat cactagtcca tggtttagag ataactttat ttattctatt agtatcaaga
    17041 ttcattaaac tccaaccaac gtttactcct tgttgaacat taaaagctgc atgataatat
    17101 ccacttgtat aaatatgtct cattaattta tcaataccat caagttcatt tccataaagc
    17161 acttccactt gttgctgtat ttgtaacttt aaagcttcaa gccttgttat atgaactctt
    17221 gcactagcat tttctaactc tttcatccac ttttgattta tagcattttc tttaccatat
    17281 ttaatatatt cttctacact ccatttaaac tcttctagtt ctcttgtatt tagtagtttc
    17341 ctagcttcta ataaagatat tccttcattt ttggcaaatc tgttgtacca tgctaatata
    17401 tctttttcta tactatttat agctagttta tattgctttt ctaattcaag ataatatttt
    17461 acacttttgt tattttgagc ttcttctaat tgttcaaatc tctttctcca ataatcatta
    17521 tgtttcatct atgccaccgt cttgattagg aattaaatca tcatattctt gttggctatt
    17581 ttctttttta atctgttttt cttcttcctc tgcattatct acaagcggat gattttttaa
    17641 attagtcttt tctgatatta ttccaacact cttagagcat atctcagcta gttctaaatc
    17701 attttgaatc atattcctag tccaagtttg caaaaccctt ttaggagaat atcctaaatg
    17761 tctacatatc attcttacta gtttagcaaa ccctaatcta aactctgttt ccataagtcc
    17821 tgcttttaat tctaacaaag tgtacaagaa tttgagtgct acaccacttg tattggcaaa
    17881 gttttcgggt ttagggtcaa caccttgacc ttggacatag atttgctttt ctgttgtttt
    17941 aagaagtgaa tctcgagctt caattggaat atttattgta attgtactta acccactctt
    18001 atcatctgca ccactacttt gtaaatcaat agttttatat tctttaagtc cttttaagaa
    18061 ctctgttaag tctgcacctc catagttcgt aagaacgaaa ataacttctt gtatatcttc
    18121 aatatcattc acaaaaccgc tataaacctt gtcatataca tcaatgaggt gtttaacatt
    18181 atctaaatct cttacctcta aatcattgtt tagaaattcg ataaatggaa cttctccaaa
    18241 attgtgttta tatacattag tttgagtttc aagtttatta tctaaatttt tctctataaa
    18301 tttattaagt atctccaatc cattgatatt actatttcca tctttatttt gataagtata
    18361 acaacattca tctgtccaat actcataaat tacatattct tttcctttat catcagtctt
    18421 tttatattct ctaagtactg caagaagctt tctgtttaaa tctgatgaat atactgctct
    18481 tatttggcga gggtctatat tagcatattg aaagttatta ttatcatcca cccaaatatg
    18541 taaccatgct ttagaatata tactagcatt tttgccaagt gttttagctt cttttgggta
    18601 tctatcgcct aaaatatcag ttatctttga atttactcta tcatctccaa catcaaatgt
    18661 aggtggataa gtaaacagat atgatatttt ttggttaact aaaaaaccaa accaattaaa
    18721 tggtattcta ttatctgcat ttcttagtgg attattagtt gtatttactt ttccaatatt
    18781 attagggctt ctatccctta taatgtcatt ttcattttta tagtattttt cagcttcatc
    18841 agctttttta acaaagttac tatgtttact attagtttgt tcaattaact tttttattac
    18901 atctaattcc aatttatcac cttcttccat ttggtgtaag tactttaatt cctgttccta
    18961 aggaatctgt atagatggca tatctaagtg cgtctaatac atcatcccac tttttaattg
    19021 gctcacctgt atttttattc caagcataca taaaaatttc tttcctgaat aaattaacat
    19081 tctcatgaac tacaaataaa gtattagttt taattctttt agctacagct tcaacgccag
    19141 acaatacagc tttattagca ttaaaagctt ttataccatt tcttttaaat gctgccaaat
    19201 gttcgggtct agcactatca caataaaact ttatatttcc atacttttct tttatacttt
    19261 tagccttatc tatccagtaa tctatttcct tatgttgagc tgaatgttct tctaataaat
    19321 ataagttacc tttatcatct tctccaatta caacaatagc tccaaaatgt tcatatcccc
    19381 aatcaacgcc tgcaaagtat cttacaaaat taatatcatt taatttatcc ttagaaatat
    19441 aatgaatatc cttattaaaa tcttgataaa ctaatccatc tgctgacacc cataaaccat
    19501 ttatatctct gtcataaaaa acgccactag gagtagactt cttaatattt gctctgtatc
    19561 tttcacttaa aaatatatta tcatctaatt tgtaatgaaa agattgaata accttgccat
    19621 ctgttttatc tacaaagtta gtttttaacc aatgctctgg ttggtctggg ttagtatcta
    19681 caagtattct agcaccttct ccactacatc ttgatttgat ttcattaaat acttcttcat
    19741 ttgcaactgt accttcattt atgtatgccc caaacgaagt catacctctt attctgccta
    19801 aatcatttgt ttttgagtgt ccaaagcaac atacttgaac tccaaacaat acaaatctat
    19861 tatgtttgtc aaacttaaac tcaatgtcat acttatttgt aagctcactt agtacatttc
    19921 tttgtaaagc tcctaaatct gctcctgcta agatgtattg aggaagctta atacctagct
    19981 cattagctat ctttctaacc cttctaagtt caagtaagaa taaatcattg tcaattattg
    20041 tttttcctgt tcttttagca ccataattaa ttagcatgaa gtagtcatta ttcaaagcaa
    20101 agttaagaac ttcaagttgt ttactatgat ataattcatc aatcattttt tatcacactt
    20161 tcgagtttat caaaatatct atcaagttta tcttctttac tttcttgatt atttatcttt
    20221 gattttaata cttctactct tgctctttgc tcctctgtag ctaaattcca atccttatga
    20281 atcatttcat catattgttt aattaaactc cttaactcac tcattgccct actctgtgca
    20341 ttaagaaaag atgcttgcct atcccatgca aattgaaatt catactctat cttttcacca
    20401 ttttctgtgc tttcatattt ctttaattct ttaaccattt cttccttgtc tttaacatac
    20461 attatctttt gtgctcttat tattgctgca tattgtattg ttatctgttc ccaaagaata
    20521 tcaaatttat ctttatcctt tatctcatta attaagtctt gggtttcttc aggtaagtat
    20581 tttgagaaga aaccaaattt ttcagcattt ttattacctg gtggaccagt agcgttttta
    20641 ttacctatgg gtgcacctct ctttttggtt gcaacttttt ttgattggtt gcaacctttt
    20701 tgtttccagt atctagttgc ccatgatttt acagtcgata aacttacatt atacttttca
    20761 gctatttcct tgtacttaag cccttttaag taatcttcat gagctaaatc tgccttttca
    20821 ttcataccac cacctcgttt gtttgtcgtt ttgggaacaa aaaaagaact ctggttagag
    20881 ttcttaatct tttagaattt accattaaac gcttcatttg catttttata aaataactta
    20941 tatatttcag caattttttc tggagttaaa gaagcatttt ccatatatgc tattgtaagc
    21001 tctgtagcta catctgcaat tgttctttga caagaaacac atatttttcc atcagacata
    21061 atagtcacct ccttataaag tatataattc aacttcaaag gtcaatatcc ttcaaaaact
    21121 attcgacaac tacaaaataa ttctaaataa tacacttatt taatttatta tataaaaaaa
    21181 gaccatccat caagacagtc atttaaatca tttctattaa ctctttaatc tttttatata
    21241 cctctttata attcatatct ttatctatta gcttaggtaa tttcatagat ataattcttt
    21301 cgagtgcttg tatatcaaac aattcacttt gatttaattc atcccttttc acaccttttg
    21361 gtatacctaa tttttttctt acaagttcag taaaatgttt ataatacatc tgaggtttat
    21421 tacttccttg actagtagca taataaacaa actcttgtat ttcatctgta aaatcttttc
    21481 ttaccttttt accctctgct cttatatcca gccattcttg gtctttttct gtagcaatgt
    21541 aataaccatg tattctaatt tgtttaagtg tttgtgtaac ccattttgta aataactttg
    21601 cttctggttt attacttcta aatgacatat tgtacacagc ttcttctgta acaaaagtag
    21661 taccgaagtt aggtaattta tctttaaagt ttctagtgta ggaatctccg acagtagact
    21721 cattaaattt ctttttatat tctctatcta tatttcttaa tgtatcacga atatttacta
    21781 tgcctagttc ctctcctacg tcatttgcat taaaccaaac ttcttctcca tttttggacc
    21841 acattacttt tacattttta tcttgtaaaa ttttcaacat actactacct cctaaattag
    21901 ttattaataa agggtgctca acttgaacac ccttattttc tgttatcaga gttactgata
    21961 tctaaaactt attaaatttt tgtataaaaa agacctagaa attaatctaa gcctttttaa
    22021 tgggggatac atattattaa gggagcaagt tctaggaatc gaacctagat taaaccacta
    22081 cctgcatggt gagtgaggtt accaagcccc acccgatttt ttagatttct gaattaagat
    22141 acaaaactgt atgagatttt aatcttaatt caaatactta atatagtgta tcaatagatt
    22201 ttgaacatag ttagaattga actaacagcg tcctcacgcc ctgcctagtc tgttcatatt
    22261 gctagattag ccctttaaac taacctagca attatttagt tttgagaggg aaatctttca
    22321 tttccacaat attattatct catggttttg ccaataaaaa gtctcacgat agtctccaaa
    22381 aagtctcaaa atagtctcat ttttaagctt tccatgaaaa aataggcaac tcaaactctt
    22441 ttatttttgg atataacata tctataatct tacaaactat cctctttctt attctaaagc
    22501 aatgacttct atctatgtgc atagcattag acatataatc catgtttatc ttttcattgt
    22561 tcatgtacat ttcattgaag aactctgttt caaagctatt tagacttgtt aatgcacatt
    22621 ctatagtttc tttttcaatt tctaatgttt tcttatcctc ttttaatcta tttaaatctt
    22681 cttctctctt aataacttca ttttcaacac ttgaacttat attataagta ggtcctgttt
    22741 tttcttcata actttgagcc ttacatccac aaaattcatt ttctaatttt ttaatatata
    22801 tatcttttat tcttatttga ctttctagtt ttttatagtt atataatcta ccttcaacct
    22861 cttgaaatag tgtcttttta ttcatacttc cacactccca tcaatttttt atgtttttat
    22921 gttataataa tatttgtata taaaagtttt atatttttga caagtggagt gtgaaagcac
    22981 tccttttttc tttttattaa cagaaattat ctttttcaaa gaaactaatt tgatttgttt
    23041 ttctctcaga ttttataatt ctgattgatt catctattaa gtttaatgaa ttaagtaata
    23101 catctttcgg gatatcctcc catttgtcag cacctaatgc caatagagtt cttttcttaa
    23161 ctaattcaaa ttcttcatta acttttgata tacctagtct ttcttttata taagaagata
    23221 tatcatattt agttttagag gttggtctat aatattctga acactctttt ttaagttgct
    23281 ctatttggat attatgttta acttccatct taagtaatga ttcattcaca atagtattaa
    23341 tttgactaag ctgtgaattt gataaggttc tatttagtaa cttttctaat cttataaaat
    23401 atcttcttat ttctcttcct ttattattgt tttgtaccat agcaagttct tttgctacat
    23461 caagcttcaa tacatattct tttgaaggtc tccctccagt tgagtttttc atatttttgt
    23521 gaaaaactga ataatcctca ttttccttaa atccatattg tttaattcta tcttcaatcc
    23581 agtctataaa ctgtctctta acttctaagt tattatgtag ttctcttgca aaaactattt
    23641 tctctcctgt atcagtttca taaactgtaa ctaaatcatc tgctacaact cttaaatttt
    23701 catttgtcat aatctcattc atatttatag tcctccttaa ataatatctt ctaatataac
    23761 ctcaaccctt ggcttatcac tatagtattt actagctaca acctcaacaa tctgtgtatc
    23821 atctttataa gctatctcat ttagtgaatc agctataatc ttaaccacat tatcaatatc
    23881 gggtttcttg ctaggtctta acacattatt tcttttctgc tctttaactt ttttactgtt
    23941 acttttagct atagaatagt aacatcttaa agtcattttt atataacctt caaagtaatg
    24001 tttaacttta gattgatata gccattttat taggtcctcg taatttttag ttttattagg
    24061 tgtataggtc cttttagtta tagagttcat tctaggtctt tctttgccaa ctggctctcc
    24121 atctattaca agaaaaactt tcattttttc accttcttag ccttctttct acattcctta
    24181 caacaataaa catccttaga tttttcctca agataaaata atttgccaca ccaactgcat
    24241 cttcttcgtt tcataaactc acttcctagt cacaaaacat ttattttatt cctaaaacaa
    24301 catacccatc ttgcagataa ttgctattat caagtaaata agtaatttct ttgcgtatct
    24361 caagacctgt gtatttttct ccatcaaatt cctgcaacac caacaagtcg ccttttttaa
    24421 aacctctatc atttttccta acttcaaaat ttttgttccc atttacaact tctttaaaat
    24481 attgaggtaa tatttttaat tcatgtatca taagctcaca ccctttaaaa gttttagtct
    24541 atttcccctt tttcaacttg ttcatcttct atttgcgata tcactcgttc gtatgctata
    24601 cgaccttgcc attcttttat tgcagcattt tcaatatctt gtacaaatat agctaacttg
    24661 ccatttacat tcgctatttt taaccatata agttcatgtg tgttattctt ttctacccat
    24721 atggtaattt ccttattttc ttccaaacat atattattta gatatatctc attatttatc
    24781 ttatacattt gagtagtaat cataatctcg ctccttttaa aagttaattt tctcaaaaat
    24841 ttttttatat tttttaataa aatatagcaa taccaatgac tctattttat tttttatggt
    24901 cctacaattt tttaaaactt ttacagtttt ctccattatt tttaaacttt ttttcatatc
    24961 ctctgctaca atactcttct ctacatatac ctccttcata acttccatct gagtaaaaat
    25021 aaacttctcc atcttcctca taagctctat atttgcaatc ttcacattta ttcattttat
    25081 tacctcctat tttttaaaaa ctccctttta taagtcaaag taagtctata gacttctagt
    25141 ttcattcaca aacttacctt gaccaattat tttatttatt ttttcttctt tcatagaaat
    25201 ctttattaat ccatgaagtt aaattttcaa aataaaatgc ttctccacaa atcggacata
    25261 ctggtaacat ttttttaccc ctgtatttac tttcaagcct cttaaaaact atcaagtgag
    25321 gtttataact agctatttct tttctctgtt ttaataatgt gtttacttgc ccatttactc
    25381 tttcaaagtt cattgctagt tcatataggg catcatatgg ttctactcta aatccacatt
    25441 ctgaacaatg aacagattta ttgactgtat ctactataaa ttctctattc ttacacttac
    25501 atttcttatc attatttcta ttaattctta atatatcaat ttcgataaca ttatctggta
    25561 aatccatttc taaaccactc ctttactaaa gaaacttatc tgtctttcat tttctatatc
    25621 ttcattacta aatcgctttt ctaggtcatt cactgtgacc ccattagctc taaaaggtac
    25681 agggctatct ctatcaaact taagcatctt ttgccacaaa atgggatagt attttcttag
    25741 tgtttttagg ctctctaagc tttgtttagg gcacaaatag caaccagttc tcttgaatct
    25801 gtgatgtatc tcatagtaaa agtctttttc ctctagatac ttcaaacaat cactttcagt
    25861 cattttttct tcaaacaatg gtgctataca gtttttttct agtcttttat atctgctagg
    25921 ttcatcgtac gcaattccaa tatacctctt atgctctcct agtttattaa aatatttatt
    25981 agcaggagca agctttaatc tgctattaca ccatgcccct agagtatacg gaaaacccca
    26041 tatttgccct ttgcgtttgc ctttttcatt tacagtataa aagtattcct caaaagtttt
    26101 ttctgcttta attcttgtta ttttaaagtt tattcttttc tcaaaatcat ctattatatc
    26161 ataaatttct ttaaattcta gtcctgtatc tatgaaaact atgtcatcta atttaagacc
    26221 tttttctaat attaaaagaa gcattgcagc cgaatctttt cctccactaa aacttgcaat
    26281 atacttcata aaatcactcc ttgcattttc taaatgattc aactaacatt tcagtctctc
    26341 cacaagtatc ttctgtaaaa tctatttgtc tcccattaaa ttctcttata taatctgcta
    26401 tatcatatac tctttgacat ttattctcta tacaatggca aatgtcattt atacttattt
    26461 cttctggtat ttcaactata atttcatgtt ctaaagttac tttttcctca aacttaattt
    26521 tatatttttt cattttaaat actcctttat ttcgtttttg agagttacaa aacacttcaa
    26581 caataattta tactaaaaga cattttgcaa ctctctaaac tgttttaatt agatattttc
    26641 tgtatataaa aatcctttta atctttctat ttctttgctt atttcatcat tccagatgtt
    26701 tatagctgta tctctattta aagaagcaac ataactagca ctttttacat caagtacatt
    26761 tttattaata actcttaaat attgactatt actccccact ttgaatctac cttttgttcc
    26821 ttctagtatt tcaacttctt ctactccttg tgaactgcat atataaagtt tatccattat
    26881 tcttctacct ccatataaag ccattctttg aacccttcgg gactttcata acatatataa
    26941 ccacaaggtt ctccctcata tatacaatac tcacaaatac aatctgtact tccaaaaaaa
    27001 ttagccattc catcctcatc caaacttttt atcatttcaa aattagtcat ttttagcacc
    27061 ctcttcattt ctcaataatt catgagcttt ttcttcatca taactgcaaa tatttctacc
    27121 atcacaataa tgacaaagta atctagtatt tttagtaatg ataggaaaca tttttttgca
    27181 aatctccaat ctatcatcca ttcttataca cctcttttgt tatcacaatt ttcacactct
    27241 ttaagattca atctatactc ataaactcta ccagctataa aactaattcc tatcagtagc
    27301 acactagcca agatgttcat tttccaacat ctccttacgt tctaagaact cttttttaat
    27361 ttcttccaaa ttctcgcatt cattaccaac tactacatat tttttgctat tcattatagt
    27421 tgctttactt gtaatttcct cccatttacc ttcaaattgc tttaaataat gccattcaac
    27481 atataattca agagcataat tttcttgtct tacaattcca tattcatatt tatttttagt
    27541 attatagggt tctttcaata tatctccctc ataaatttct tcattatttc cagaccaaca
    27601 tttagagaat actccaacat tagatacttt ttgccattcg caattctctt ttagcataaa
    27661 taaacaatct actgcatcac tccactttat tgtttcagaa taaatccact tctcattctc
    27721 aaaatcataa cctctgtact taattaaact cacttttaat catctcctca tattcttctc
    27781 tagccttatc tatagcaata aatatgtcct ctccattgtc atacaactct tttgctcttt
    27841 taattgtgta ttcagtcctt gaaacttcca ttattcctcc ttaatatatt cagctttcca
    27901 gccacttctt gttttagttt tctttttaat tgtttggtaa actgcctgac tctgtagtct
    27961 taaaaaacac gctgcactat ctatagaatc aaatattttt tcttcaccag ttttggcatt
    28021 aatcaacttt acctttgaac ctttcttttt cttttttcta tttttatcaa cattaaactc
    28081 tattagcatt ttttcagaag ttggaaatac aagctctcca ttttttctta ctccatgaac
    28141 acaacaatat agtgctaagt agtttctaag agtcaaatca tcttcaaata tgttatctgc
    28201 aacagaacca ttaaaatatt tttcaacctt taacatttca gctccctcct tattcaactg
    28261 gcatttcaaa cactttttct ttgttgcatc taaccccgtc tttatttata atgtcaaact
    28321 tagttcctgc aataacagca ttctgtatca tgtttaatac ttcaatagct ctttcttctg
    28381 atttatacct acctatttct ctagcatttg attcctcttc aaacactgca catacttgtt
    28441 tattacttat ttcaactcta ttaactctca ttaaatctaa tctatcttga cttctaatta
    28501 ttatcatccc taatctcccc ctcatcacat cttcttatat catttaactt acttaaatct
    28561 tcatatatat tcccatcaat cttaactatt gcaagttcag ataatctaaa gcaatctcct
    28621 gacatttcat tcactgcaat aaaacaacca tctttaaatt ttacctcccc tgcaaactct
    28681 gtaaaaaata tacttctaca taaaacaata tcgccttcat agatttcttt tccatcacaa
    28741 tcctttaaac ctgtgtatat cataacctca aaattttcat tgttttttgg caaataaaca
    28801 ccactataaa cctctctaag caaattttta gaatagcaca ccatttcatc ataactatac
    28861 atttctttac catttttatt ccattctcta aattttaact ccatctttca tccctccaat
    28921 atttttcaac tcctaggaag taatattgta taactacccc ctagactatt taacttaatt
    28981 aaaaaggtat atcgtcatca tctattgctt gaaaaccttg tgggtctaat cctggtagta
    29041 catattcttg tttagcatta ttatcatttt tactagaaag tagttctaag gcatttacat
    29101 taaccttagt aatagatttc cagcaaccat tttcatcttt gtaattatat atatttaact
    29161 ctccaatagc atagacaggc ttagctttaa caagatattg cactagattc tctacatgtt
    29221 ttcctaattg ttcacattga ataaaatcag ttattttatt tccattttta tctttaaacc
    29281 ttctatctac tgccattgaa aaggttattt ttggagtacc cgaatttgga aggtacttca
    29341 attctgcatc tgcaactaat cttccaacta aagttattgt attcatttaa ctagccccct
    29401 tctatttttc ttcctgctct tctgtatact caacaaagta agtataagtt gtcttgctat
    29461 tttgcttctc tctagcaatc tttactgtat atccagcttt cccaagtaat cttaataatt
    29521 ccaatctatc ttgttcgttt aaagaaccac ttctttgtgc atatattctc gccattttat
    29581 acctcccctt tctaggaagt aatatattga tatttacttc ctagaagtat aattttattt
    29641 aaatttaacc ttttgacttt tcttaattat gtcatctagt tcgtcaggtg aatattgagt
    29701 aaaggtttca ttgaagttat gaaacttatt tttactcaca ttaggagtat tcacattttt
    29761 atgattagac tgcttcttct cctgtttatt ctttttcttc ctctcaaact cattttgata
    29821 ctctgtaagt tctaaattag tttttacacc tgcttctatc caattgttta atattgtctt
    29881 tacatactta taattcttaa ctccatttga tattgcttca tcaatagctc ttataattac
    29941 atcagcttcc attccatcat ctaagtaact cattaactct ataaagttat taggagtaat
    30001 cacacctata tatttttcaa agtatttttt tatataggtg gttttatctt gttgaggttg
    30061 ttcattaata acaatagtag taatatcatt atttacttta aagtcattac ttactacttc
    30121 cgtgttttcc ggtttccgag aaacccggtt tccgggaaat ccggtttccg ggaaatcagt
    30181 ttttcgggat tttagcttct gaggattttc aagtggtatc tcatatactt gataatcata
    30241 tcctccaagc atcttattag tattagaatc tcgacaaggt gttcttgtta tatatccatt
    30301 ttctatgagc tcccttaaaa tatttgctgt agcatccctc ccatttttac ttcttttata
    30361 taaatcatta acatagattt tccaatggtc gggcttacta atcagatatg aatgtaaacc
    30421 ttttgcttgc cagcttaatt ttacatcttc caaacaagtt ttatttaaaa ccacatatgg
    30481 attatctttg tctttgctta ctcttataat ccccacaata tcacctgccc ttattgctta
    30541 ttttcataag cattacaaat agtgtcatac tcttgttttg ttaaatcttt tatctctttt
    30601 ccaaatcttt taaatacttt ttctttcaaa ctttctttat caacatttgc attacttgct
    30661 attgcatata acctacttaa ttgtttatct gttaaaattc tattgttaga attactttta
    30721 gcttcatttt tgccactggt tgcgtcaaaa gtgtcacttt cagttatatt aagtaactga
    30781 atatataaat atctagtttg ataggtttct atacctccta gtgcttgtaa ttcattagaa
    30841 cctttaagtt gcaagtctct cattggagaa gtgaatacaa tctgctctga tgggttttct
    30901 ccattaatta atgttagagt tgcatattca tttgtaaagg tcactatagg gcatagctta
    30961 gcttcttcaa gtaatccagt tgcttgtggt agaaagtctg ctaactcaaa atacttgaag
    31021 ttagcgaact tattttctcc acttttcttt aaattcaact tactaaattt aactcttaca
    31081 ttcatcaatt taatgtaaat attattaatt tccatggtcc tcacctactc ttttttagct
    31141 tttggaattg ttagtgtagt tccatattca atcctgcaac cttcgacctc atgacctttt
    31201 ttaataaagt cttttatact atttttatct acttttacaa cttgctctac tgttttatat
    31261 atagcaggta tcttttcttc atcttctatg actaagctac ctgctgactt tcttatactt
    31321 atatttccta aaaatgtttc tactttttta gtaccaagta gttccataca ttcctttata
    31381 ttgcttttta atctgtcaag agcattcttc ttaatcttct ttaactcttg cattctctta
    31441 atctctgaat ctatagagtt tatatcactg tcaatgttta atattactga aactatccta
    31501 gtgtttttat tttgtatctc ttgttttatt atttctttta tttcctctag tttttcagtt
    31561 tcatttcctg ttgtttctgt taaaccttct tctatttcta ataaatctgt agttaattca
    31621 tataaagtac tcataatttc cctccgtttg tgctataatt agcttaatta aattttgata
    31681 tatttatttg aattgagcca cggcaatggc tcttttctta tatctgaaca tctataggtc
    31741 tatctctttc aagttcttct aaaattaatt gaaatatctt gcaatcctca ttttcttcat
    31801 attcttttat ttcaatttgt gtatctataa tttctagtaa tgactcagca aatattttta
    31861 atctttcgtt tacacttttt tctcttaaag cattactcaa ttcaatttct tctgatatat
    31921 ttctttcttc tttttttcta agttttgtat aaagttgctc gtttttattt atttctaaat
    31981 tagctctatt tagttgttgt tctactgcat ttctcactat aattaaactt ttcatgatta
    32041 atccccctta atttagcatt tcaatacaat aatcatagct tattgcatca tctatagtta
    32101 tagacgattg tactaaatca tctaattctt tatcaaaata aactactgtt aattcaaatt
    32161 cttgtgattg agttattata caatcgcttt caaaaccaaa tcttgcacat gttactctga
    32221 ttgctttacc tgctttaaga atttttgtag gaaattttac tttaagtatt ttcatatcac
    32281 tatcccctta ttgtattttt taagaccttc aaaacttgct ttcttattgt attgcttaca
    32341 gaattgtaca taagctatca gtactcttac attcaactaa atcaccccct ttcttttttt
    32401 cattacatct ttatctttca ttgcattttt cataataaat tcttcaaatg atattctatc
    32461 aatcatgtac tttcttccta tttttaaagc aataaaatct tttgttatca tggcttctct
    32521 tgccatgttt ctagctgtta catcagatat tttcaagtac tcacaaaatt cttctatagt
    32581 cattaactcc attcttttaa ttccttctct atctaaaaac atcttgatga tgtctgttgt
    32641 atcatctctt cgcattaact cttgtactaa gtcttttgtg tctatgaatt gtaatgctac
    32701 actcattttc aaacctcctt ctcatattaa ttgaatatcc tgtatttagt tttcaaggta
    32761 ctgtcatgat ttaacctaat ttttgcttaa atcacttgat attccatatt ttaaagccat
    32821 atcttttaca atagccacat acccctctat tagcttctta tcatcttgta ttacatctaa
    32881 attgttaact ttctctcttt tagattcaga tacaccttct tctgccattt ttcttctttt
    32941 attgattaat cttctatgta ggtcaactcc aaatctctta tttaataatt cataactttc
    33001 tgttctaagc atatttatat gttcaaaacc accttgtttt tttgctattc ttgcaattag
    33061 ttgatgtgta tttgttctcc aactatttga gtctaatgaa actacatctt ttattgtttc
    33121 aacctctgtc tttgcttcta aagcaatgct atttgcttga ttaacttgaa gtcttaaatc
    33181 tttcatttct tttaaacttt ctattaatac atcttctata caagttggct tatgttgctt
    33241 aactttgaaa tatgtttctt ctaagttatc aaactgctcc caagctttgt cagtatccaa
    33301 tattttgcag tgtctatttg ctcctctttc agtccaaaga tacatttttg aagtaaattt
    33361 taggttttca tattctgtat gaataccttt aaaatttttt aaatcatcac cttgcaataa
    33421 aaaataatgt ttaccttcaa taaatctatc tttgttattg ttaaaattgt tgcttatatt
    33481 tcttgcatct gtttcatata catctgctag ttgctgtgta gttaaaactc tttcgttatt
    33541 tctttctatt acttgtaagt tattcatatt tttcagctcc tttttcttta aatgtacttt
    33601 tagtacagtt gtttttcaaa aaaatatact ctattgaagt attgaaataa gctgctattt
    33661 ttacagctgt atttagagac ggtactcttt cgccattctc taagaaagct atatacctac
    33721 ttgtaagacc taattcagct cctaactgat ttctacttag tcctttttgt attctaaaat
    33781 cttttagttt attcattttt tcaccttctt ttactttatc ttatgtacta atagtacagt
    33841 actattagta cattgtcaat agctttttta aaaaaaatga gctataattg ataattaaga
    33901 actaatagtt caatataaat taaaaaggtg gctaaataac atgattggat atagaataaa
    33961 ggaattaaga aaagaaaaag atattactca aaaagaactt gcaacttttt taggtcttac
    34021 tcctaaaatg atttcttttt atgagaagga agaaagattt cctccacatg acataatttt
    34081 aaaattatca gattttttta atgtatctac agattatttg cttggaaagg tcaatgtaaa
    34141 aaatatagac aatcttagtg agttagagct aattgaaaat ctaaatttct ctgatgatat
    34201 aaaagaagct ttaaaactaa ttagcgaatt aagtccttct agtcaagaaa aaatgttcaa
    34261 aatagcaaaa gtatttcttg aagaagaact taatgagaaa aaataagaaa gagaagaaaa
    34321 ctattctctt tcttttttat tttcttgttt ataatattct tttaataatt ctatgtactt
    34381 ttctaacttc tcactattat tttctcttaa tttgttcaat gtatcccctg tgtcaattag
    34441 tagttttttt gatttttcca cacgccttcc ccctactatc agaacttacg ttcttatttt
    34501 tagtcaaaat tccctaatga attttaataa aatataacta tgtattttca tttctaaaaa
    34561 tatttttaga ttattcaaaa ttttcttgga taattatctt acttacataa taatactttt
    34621 gttaaatata tgcaataaaa aaaggggaat tgtaacaaaa aaatcgaatt ttgtagagtc
    34681 ttggttattt tttccattcc tgtgtattat taatcgtctt tttaattata attttttgta
    34741 ttttcttgtt tatataatat tttttattat ttaattttaa aatcttcgtt ttacttttta
    34801 taccatataa atatagtatt cttttcaaaa ctatttaatt ctatgttttt tcctaatata
    34861 catagcattt atacagaaag ttttatatac ttaaattgtt attgtcacaa agtagaatac
    34921 actagaaatt aattaaatac aaaaggagta attttttatg agcattttga atctatttag
    34981 aaaaaataaa aacaaaaata atgttgattg caatgaaaaa tcgaacgaat caaaacaaag
    35041 ctataatgat agtactacac tttcactaga atgtaattct aattcacctc ataacataga
    35101 agtaaaaaat gaaattaata aagtgctgaa tgtaagttgt aatgatacaa caaatttata
    35161 tgaattagaa aaacaagcaa gagaaaaatc agatgcttta tatgatatac atactaatag
    35221 tattaataag tttaacccac aaaacaatat attagaaaca gatactaaac cacttacatc
    35281 aatagaaaaa tctttcctaa aatacataat tggagaaaat atatacgagc cttatatagc
    35341 aacctattgg acatatgaat ataatattaa ctattcatat ttaatttcta agtttttcaa
    35401 catggattat cttaagattt caaattacat tgaagacctt actaagttaa cagtttcgga
    35461 attgaaagaa atattaaaat ctaataatat taaatcaact ggtaaaaagg ctgaattaat
    35521 agaaaggata gaaaaagaaa tctcatgcaa agatttatct aattttttta atagctccaa
    35581 caaatattat gctttaacag ataaaggaaa agaactgttg aaagatgtgc gtaaatctgt
    35641 tactaaaaat actgacctag aagaccagtg tttagaatta atttatattg ataaatatga
    35701 ggaagcatat gacttaattt gtaaatatga atcctctaaa aatatccaaa gaggaattaa
    35761 tataaactgg gaaaatcata aaattacacc tatgaaaatt gagtcttaca aagccataaa
    35821 ggaattagat ataaatttaa aagacacact tttagataac ataattaaat catcctatat
    35881 actttgtgat atgttaggaa ataactccaa aacttctata ttagtaaaac gtttggtagg
    35941 agaaaaaatt gataatatcg aaattaataa tgctataaat agtataaatg atgtaatata
    36001 caatcactct actataacat ataacgcaaa tgatagtatt aataataaaa atttacatta
    36061 tatggatatt gttaaaaata acaaatcaat accattcgaa gttaataata aaaattacaa
    36121 cttcaaaatt aatgaaaatg aaatctactt ttttaatata cttaaaatta aaatgtacga
    36181 aaatgaatta aaaaataatt ttgtctttga tagaatgtca gatggagcat ttaatgtatt
    36241 tgatacttca gataacttca ttggtaaagt taaattgcaa ggtagaaaaa aatggataat
    36301 gtacacgaaa aatgaatttg gttcagaaca tatttatggc gaattaattc acttaatcga
    36361 tggtattgat gcttggatta aatattcaaa ggagtatcta aaataataaa agagctactt
    36421 aaaatgatta aaactaattt taagtagctt ttccttatgt tcaaaatact gataacatac
    36481 ttttataaga atgttatatt atttttataa tttctgttaa cataccttta taatccaact
    36541 aaattctttt aaataactac cattttgttt tatttttacc tttttttgca aatatatgga
    36601 aattgcacat aaaattttat atacttaaat tattattatc ataaagtaga acaaaaaata
    36661 aaaaaggagt tttgatatga acaatgaaaa tgaacagtta aaaagtgatt tactcatcaa
    36721 cgatgaaaaa atcaaaaatc ttaatttcaa gataccctgg tattattctt tatggactat
    36781 atccatacta attctttcta cgttttcaac atactctata tcatttatag ttgcaataat
    36841 attcttattt aaaagaaata agataatgaa aaaacataaa gatagcatta gtatactatt
    36901 atctgatgtc gaaaaaatca ataataaata tattttatta aatgatgaaa ttaaaatgaa
    36961 agaaaaacac tttgaagatt tatgtgaatc aaatgaaaat aagttaaaag aattatccaa
    37021 tctattagac aaaaagaaag ttgaaattga taaatttgat tcagaaaacc aagataaatt
    37081 taaacttatc gaagaactaa aaatagaaaa agaaagactt gataatctta taaaagataa
    37141 aaatatactt aaagataata ttaatacttt aaattctcat ttagaagaat taaaaaatga
    37201 aagggaagag cttagagata taaacacaac tttaaaaaat aaaaaagaag agctaaaaag
    37261 attatcagaa gaattaatac agactgaaga tgaggttctg cttcaatcat ttggattata
    37321 taatccaaaa tatgattttg aaaactctga tgaatatatg gaaaaattaa aagaaataag
    37381 agaaatgcaa aaactattaa taagaaataa aacaggtgta aaatattctg attcttggac
    37441 tgttgatgga agtgttcaaa aaggtagaac tatgactaat caaaatatta aaacagctct
    37501 taaactcttc aatagtgagt gcgacattgc tatgtcaaaa gttagtttta aaaatattga
    37561 ttctatagaa aaaagaatac gaaaagcatt tactgataca aataaattaa atacttcaaa
    37621 taaggtttct ataaaagaaa actatcttaa tttgaaaata gatgagcttt atttatatta
    37681 tgaatacctt caaatgaaag aagaggaaaa agaagaacaa agagctttga gagaacaaat
    37741 gaaagaagaa gctcttgttc aaaaagaaat tgaaaatcag aaaagaaaac taaaaaaaga
    37801 agaattacaa ttcaagaatg aattacttag actaaaatca actatcccag aagatgaaaa
    37861 tgataaatta gaatgggaac aaaaaattaa ttctatagaa gaaaaactag ctttgctatc
    37921 aaaagattta gatgatgtat taaatagaga acaaaataca agagcaggac atgtatacat
    37981 aatctccaat attggtagtt ttggagaaaa tatatataaa ataggagtaa ctagaagatt
    38041 agacccaact gagagaataa atgaattaag tagtgcatca gttcctttta aatatgatat
    38101 acatgcgact atatttagtg aagatgcacc taaattagaa tcagctttac ataaagcttt
    38161 tgataataag agagttaaca aggtaaataa tagaaaggaa ttcttcaaag ttacgcttga
    38221 tgaaataaga acagaagttg agaaaaattt cgataagact gtggaatata caaaattggc
    38281 agaagcacaa gaatatagac aaacattaaa aatacaagaa ttaaataata aattagctta
    38341 aatatattca aacaattata ctttaataaa atattatttt tgaatatcta taccaatttg
    38401 tgatataata atagcaagga gataaaattt actttttaaa aggtgaattt ctctaattga
    38461 ttagaattta aaagttattt ctttaaatca cccttattgg cgtttgggtg attttttatt
    38521 ttgtcatata tgaaagctga tacaatacca gctactatac tcaataaaaa gttaattaac
    38581 atataaattc acctccttcc tatattggaa tttggcgttt atatgagaaa atcacccttc
    38641 gcttttcaat tttattttcc ttgctaaaaa tattataaca tataattctt acatatttta
    38701 cctatatatt acttttttaa agattcgtct atatatttct gtatacatct actctatcat
    38761 cgaatagaat ttataactta gatttgatat aataaaacca tagttattca atatatttta
    38821 aacatgaata atacttataa aggagtgtac atatatgaat atcaaatcag cttttataag
    38881 aaaaagaggg gaaaaatttc atgtatatgt ggagtacata gaagaaacaa ctggcaaaat
    38941 aaagcaaaaa agttatggaa gctatgaaaa gaaaaaggat gctgaaaaac atttaattga
    39001 aataaagtct actataaaca ataataagtt tataactcca aacaaaacaa ctcttgtaga
    39061 gagatgctat aagtacataa tgacaaatga aaaaaattgg tctccttata cagttataaa
    39121 taggaaatct tgggttaaga attatataga accttttttt aaagatacaa tattgataga
    39181 tgtaaaccct agccttcttc aaatctttat agataaaaat tttgatggtt ctgcaccatc
    39241 aactgcaaaa gttagatata attttctatc ttctgtttta aaagaagctt ataggctaaa
    39301 agaaatatct gaaaatcctt gcgattttgt aaaattgcca gctcaaaatg ttacatatga
    39361 aattgaaata tataatagag aagaaacgct attgttaata gagaagttga aagatagttt
    39421 gatagagata cccattctct taatgttgct gttaggttta agaattggag aggtagctgg
    39481 tcttagatgg tctgatgtta atttagataa tagtataata aatattaatc aaattctcat
    39541 atatgcaaat agcaaaataa cttttaaaga accaaaaact gcaaaatcaa aaagagcgtt
    39601 atctgttcca aaagagttag ttgaaaaact aaaaatagaa aaattaaaac aaaacaaaat
    39661 gaaattacaa ggtacactta taaatgaaaa taacttagta tgtctaaata caaattttaa
    39721 tgcttggata ccaactgcat taagtaaaac ttttcataac tttattaaaa gaaataattt
    39781 aagaaatatt agagtacatg atttaagaca cacaaacgca agtttgcttt tgctaggagg
    39841 tacaaatatg aaagttgttt cagaaagatt aggtcataca gatataaaaa taactatgaa
    39901 taggtactct catgtgttag aggaaatgga caaagaagct tctgataatt taagtaaact
    39961 tctatttaaa taataaaaac tgactgtcag ttaaatgtca gttgaaccta aaaaaatagg
    40021 ttttgtcagt taaatgtcag tcagttagtt tataataatt tcttttaaat accgctaaaa
    40081 ctgcacgttt taatacttat ttatgtttgt ttatatgtat ttattattct ttattaaaat
    40141 aatatcctgc tcctcttatt gttataattt tctgaggatt tttataatct ttctctattt
    40201 tctttcttaa tccattcact gcaactacca cactatagtt atcctctaag tattcattca
    40261 tccatacatg ttcatatatc tctttagtag tcaaagtctt ttcaggattc tctataaaaa
    40321 agtttaacaa cttattttct gttggagtca attttattat tttatcttct aactttatta
    40381 ctccactagt tctattatat tcctctaatt ttgtattatt ttcattatta tttacatatg
    40441 agttcattct tcttaaaata gcttttactt ttgcgtataa tatttctaaa tttagaggct
    40501 ttattaagta atcgtctcca ccagaattta aagcatttaa aatgctttgg tcttcattta
    40561 tataagtcat ataaacaatt ggacaagtag ttacatttct aattttttta caaagagtcc
    40621 atccatcacc atcacttaga attatttcta aaaatattaa atcatattta ttgctaaata
    40681 tttttccaat agcttcttca caattatatg ctaaatctat acttattcct ttttcctcca
    40741 gaaatccttt tagcttcttg caattatcct tgtctccatc tattatcaat atcttagttt
    40801 gcattataat cactcccaaa tatcattatt cttttatatt aaataagcta ttattataaa
    40861 aaatatagac ttaattttat tgtaaaaaca gttccttttc ctagttctga atctacaaag
    40921 atttctccac catgctctct tataatggat ttgacaatat atagccctaa cccttgccct
    40981 tttggctcat tattgtctct ttctgtaaag aatctgtcaa atacctttgg tatattttct
    41041 ggaggtatac cttttccatt atcagaaatt ttaataattg caaatccatc ttctttatcc
    41101 attgataaaa ttatctttcc atcaaatgga gtaaaggtca aagcattata aattaaattc
    41161 tcaaatgctc ttgtaagcat ctctttattt atctttgcat atattttttt ctccaatacg
    41221 taagtttcaa agtttacacc acatgcttgt gtatctggca aattattttc atatatctct
    41281 ttaataaaat tattcagaca tattttttca ctaataccaa tgcttttatc ttgtgatgta
    41341 aattcttgca aactacgtac tctattttgt acttcatttg acttttgatt tatagcataa
    41401 agataggttc ttgtctcttc atctacatga atattaccaa cctttatcaa atctataaat
    41461 gcttgtatag ccgaaacagg tgcctttaaa tcatgtgcta catctgccaa gaatctttta
    41521 cgttcattta acaatgttgt aagttcatta gttctcactt caacttcatg ttcaagattc
    41581 cttgtaagtt tttcattctc ttttattatt attctattcc tgtttatcat cataacagaa
    41641 aataaaataa caattacaaa cccacaatat tctgtttgcc accctgtaaa tataggctca
    41701 aatctattac tcgtaactgc atcaaataat atgctaattc caaaaacagt gtttactgaa
    41761 actaaaatat aagaacttat atgctcagag catgtctttt tatatattga aaccagcgaa
    41821 gacattaata tatatataaa tacaatatat ttatatatgt ctattaactt cccatatatg
    41881 ttgacaaagt acatatcata tggaagaaga ataattggta tcactataga tatgatactc
    41941 attgtaattc ctaatggtaa aattaaaaat ctgtacactt tattttcttc tattttggat
    42001 atacttccat ttatacaaat aatacataaa actaccataa aatatgacaa atcttcaacc
    42061 gcatatgtaa agcttaccaa aggcagtcct aacaaatgta caaagggata ggatacatgg
    42121 atggcaaaga aaacacacat acatccaaaa tataagtaaa ttttactttt gtttgaaaga
    42181 aaccatacag acaatgaaaa tatagctatt gcaaaagttg tgaagcaaat tatactataa
    42241 aaaagtaatc gataaaacat catattactt atgtcctttg tttctcctaa tgcaggcgga
    42301 taatacaaac cactataata atgtgaaaaa ttcgatacat tgattataat ttctgtattt
    42361 ttctttgcaa taaaacttac tactgaattt ttaattttgg gtctatattt ttctgttcct
    42421 acatctccta atttagaaac catttctcca tttatccata cttcacttgc ggaaaaaatc
    42481 tcaggaagct ctaaacttag tagcttatcc ttgccttcat tttttattct catacgataa
    42541 gtagcattcc catatggtga ctgagtcccc tttctcatag aaaaatctgg atattgacct
    42601 ataaaaacat attctggttt tatatcttgc tctgtaaaat cattcggttt aaatatttta
    42661 tgattataaa actcccagtc atctatcaaa aagacaagtt tacctttagt gaaagtatca
    42721 ttatctatag ttaaaattcc attacttgct ctaatagact tatatgtata tttattatca
    42781 tatttataca gaagatttaa tcctgttatt gccaacagag agactatcaa tacaatgaga
    42841 gttcctttta gtatattata ctttttcatt gtatcaacca catctctttc atagtagtat
    42901 taaataaaac aagaactatt tattaattac agtatctcac ttatggtaca aacttatatc
    42961 cttttcccca tacggtttga atgtattgat gctccctgct taaagaatta attttttttc
    43021 tcatctgtgc aatatgaacc tgcactgtat gttgatctcc aatatcaggc attttccaaa
    43081 cttggttata tatctctatc ttcgaaaata cttgttcttt gttttcagct agaaacaata
    43141 atatttcaaa ttccatagta gttaaatcta tactttctcc atcaaaagtt acttttcttg
    43201 aatttacatt tattactaac gctgaaaact ttaacacatt aggaactgat gtaatatttt
    43261 tgtactgcct catacgagca tatattctaa gttcaagttc ttttaaacta taaggttttg
    43321 ttatataatc atccccccca gctaaaaatc cccgaacttt ttcttcttca tgctcataat
    43381 tagataaaaa tattataggt atgttaacct tttcttttat atcattgcac attttatatc
    43441 catctatatc tggcaatgaa atatccaaaa ttatacagtc taaaactata ctctctacta
    43501 tatccatagc atctttagca gtctctgatg tatatacatt aaaacctata ttagaaaaat
    43561 aaatttgatt tatgtttaaa atatcaacat catcatctac aaccagtaaa ttatacatta
    43621 caccactcca ttcaaaggta ttttaattat aattccaagt tttatagtta ttacaaatta
    43681 taatgtttta ttttcatata taactggtat tattatttta taatatcttt acaaactaga
    43741 ctataatact taagtatttt tgaataattc ttgaatattg tattaaacat taagattcat
    43801 tattaaatac taattaaagt ctccgattgt tggagaatgg agcttaaagt cattttcacg
    43861 tataaattta ttatttttct agaaacttgt ctattggcta gtttgagtat tgatttatat
    43921 gatttatatg gttataatat aaaataaatt gtattatttt ggtaaatata ttgttacaaa
    43981 aggtttatat tctgcatctc aatgtttata aaaactttat tttcttatta taatactatt
    44041 attcttttaa aaaaatttcc cttttccaac aaatggctac tttaaaagcc aaaattttac
    44101 ctatcaataa aaatcttaac gactaatact cttattttca aattttgcaa catatttgtt
    44161 aattttaaaa caaaaaaaga ctatgcaata taaaaattat attcatagcc ggttgcacca
    44221 ctaactccat atatctctag atgcccaata ataagatata cttctcagtt tctaaaatat
    44281 ttttattaaa aatcttttat atattttcat aaatttcttt tttattctaa cattgtaata
    44341 ttattttgtc aatatttcca tattcttaga gataagatac taaaatacct attttatcta
    44401 aagatattta tatttctaca ttcaataata gacaataccc tgcaagttaa agcatcattt
    44461 ttatgagctt atctcacagg gtattatatg tttactttat attataactc ttgttattga
    44521 ttaactttaa taaatccttt ttctgaaaca agtgcttgtc cttcatcact taatatataa
    44581 tctattaaag ctttaccttt ttctgacaaa ccatcttctt tattaactaa tataaatggt
    44641 cttgatattg gatatttatt agctattaca tttgcatcag ttgcttcaac atcatttatt
    44701 tttaaactat ttactttctc atcaacatat ccaaatgata tatatcctat agcattttca
    44761 tttccttcaa ctgtagtttt tatatttcct gaaccatcac ttatttgtgc atctttagtt
    44821 agttcttctg aatcaaaccc tacaatttct tggaatccat ctctagttcc tgaaccttct
    44881 tctcttgata ctattactat tggtgcatca tttcctccta cttctttcca gttagtaatc
    44941 tttcctgtat atataccttt aacttggtcc attgtcagat tttttactga gtttgcagta
    45001 ttagttatca atgctatacc atctattgct attttagttt cctttaatcc agcacttttt
    45061 tcttcatctt ttaaatctct tgaactcatt cctatttcag atgttccttc tatagcattt
    45121 tttatacctc cagaagaacc aatctgttgt acttctacac taacaccttg atttttttct
    45181 tgaaactttt ctccgatagt ttccataaga ggacctattg aagttgaacc tgaaacagaa
    45241 actttgcttg aatctcctga atcacctgaa cctcctgagt tagaactaca tcctactgct
    45301 aaagctccaa ctaacattgt actagctaaa agaacgccta ttttcttttt aaacatttta
    45361 cttacccccg cttatatttt aattttttgt tgtcattttt ctatatttta ataatacaga
    45421 ttctttgtta aatgaatatt agagcagggt taagtaaatg taaatattgt taaatacatg
    45481 taaaaactta attttatatg atttattctt aattagatta actttttaaa gttactttag
    45541 gcagatataa acataataca actcatatta tcagaagtct tcattgaagc tatcaaccta
    45601 tcacatccta taattctttt tctagtttat taactaattc agcaaataca tttaaggctt
    45661 cctctataga ttcttttttc gtcatatcta caccagcaga ttttaattgt tctagtgggt
    45721 attctgaccc tccacttttt aagaagttta tatatctatc tactgcagta cttccttctg
    45781 aaagtatctg ttgacttaaa gcacttgcag cagaaaaccc tgtggcatac ttatatacat
    45841 agaagtttga ataaaaatga ggtattctcg cccattctat tcctatttgt ttatctacta
    45901 ttgcagattt tccgtaatac ttttcattta atttgtagta tatattagta aattcatcag
    45961 cagtaagtgg ttctccactc tctacccttt gatgtacaat tttttcaaat tcagcaaaca
    46021 tagtttgtct atgaactgta gttctaaatt gttctaaata ataatttaat aagtatatag
    46081 tttcatcctt agacttagaa ttttctaata aataatttat aagaagtaat tcatttaatg
    46141 tagatgcaac ttctgcaacg aatatcttat agtccgaata taaaaatggt tgacttgttc
    46201 ttgaataatg actgtgaaca gagtgcccta attcatgaat taaagtgaat agagaattaa
    46261 ggtcattttt atagctcatt aatatataag gatgtgaatc ataacttccc caagaataag
    46321 ctcctccttt tttaccttca ttatcatata catcaatcca cccttcatca aaagcacttt
    46381 ttatgacctt caagtattct tctcctaaag gtttaagtgc ctctaatatg atatcctgtg
    46441 ctttatcata tggtatatcc atgtcaaatt tatctgtcaa aggaacatac aaatcataca
    46501 tgtgtatttc attcaatcct aaaaatttct ttttaagctc aacatattta tttagattag
    46561 gaatactttt atctatagct gatataagat tattgtaaac atctaaactt acatcatctg
    46621 aaaataaaga cgcttctatt gctgaattat actttctagt ttttgcgtaa aatatctctg
    46681 attttattcc accataaagc gttgaggcaa atgtattttt atatttctca tatgttgaaa
    46741 attcaccttc aaaagcgtct tttctaactc tactattctt actttttata aataaagagt
    46801 agtttgaatg agaaagctta accttattcc cctcctcatc ttctatctca ggaaattcca
    46861 tatctgcata tgctaacata tcgtatacat tttctggaat tgtcgataat tctgatgtag
    46921 ctgcaagtat ttcttcctct cgttcactca aagtatgtgg tttatctctc aatatatcct
    46981 ttatatattt tgcataaaag gatagcttct catcttttaa gtattcactt aacttattct
    47041 cttctatcgc cagtatttct ggaactatat aagaagtagc cacacctaaa tcagtagata
    47101 acatttctgt cttagtggct cttccttgat tatcattaat tctagtatct tcatgttgtt
    47161 tcatatgagt atatacatat aaattttgaa caatcctaga tgcattttca gagatattta
    47221 atactttata taagttctcc ttactctcag aaagcttccc tttatattct tttacttctt
    47281 ggataagatt ttttacttta cttatgtctt tttcaatttc ctctttactg gagtacatct
    47341 tatctatctt ccatttgtac ttttcttcta ttgtacttct atcagttccc atatcataca
    47401 cctctatttt aatttgtttt atattttatt cactttacaa aatatattgt atatatttta
    47461 gtccaaataa tctacattta ttactccttc tatcatattt atttctttca taacgtcgtg
    47521 taagtgtatt ctcttagcat aagatacaaa aaaattaacc ttccagtatt cttcattacg
    47581 acattctatt tccatatttc ttacgataag ttgatttttt tcaaatttat catataaaaa
    47641 aggtatagaa tccaaattgc ttaattttaa tatcaataca ttcttttctt ggctaaataa
    47701 aaacgtattg attatcctaa gcacaaataa tgctatcatt acaaataatc cacctagaat
    47761 tgccaattca taataaccat atccaactgc tataccaata catgcagttg cccacatccc
    47821 agcagctgta gtaagccctt ttactccacc tttatttttt aaaattgctc ctgcacctaa
    47881 aaaaccaatt ccagataata cttgagcagg cattcttgct gggtcagcat ttgtatacaa
    47941 attataatca aagaataatt gaatcgaagt tattgaaaca atacaagaac ctattgcaat
    48001 tagtatatgt gtcctaaatc ctgcaaactg tcttattttt tctctctcta agcctattat
    48061 tcctcctatt attagtgcta atagtaacct tattgctatc tccttacttc ctatatcaat
    48121 cataatataa aaccctcctg acttaattac aacttatgtc ctacagataa tttacacatc
    48181 agaaatacta ttttatatct taatattatt attaatatat gtaaaatata gccatctgtt
    48241 aatttttgat acaaaaaaac ccacaactgt gggctatttg cttaggtaca tgtatttatt
    48301 tattaatata tctattttct tacttgattc tactaactct tcttgaaata tttctggata
    48361 ttctatgtat gtatttatct cttccctaac tgcttcaatc tcatttttta acgcttctaa
    48421 ttcattgttc gccataataa tcaccactat tacaaatttg tatattttta tatacatttt
    48481 atcaaacaat attatatttt gtcaatatta tgtcaataaa acttactata aaaatgcttt
    48541 aatttaggta ttgtatacct ggatactaag cctacaaaca taccagttac taatgatgcc
    48601 attaacataa atggtaagta ccctatagca agtatatttt ctatgattaa acttgcaact
    48661 attaattgac ctatattatg ccctattgca cctataatgc ttatccctat tagtgataaa
    48721 tcttttattt tactcgctaa atacataaat aaaagactca gataagctcc tcctatacta
    48781 aatagtagat atgataaagg gcctgcaaat attgatgaca aaattaccct gatagtaaca
    48841 attataacag tatctttgac acctaacaac attaatgaaa ttaaagttat aatattgctc
    48901 aaacccaatt ttgcccctgg aaatataact ataagaggat ttggtatata tgtctctaat
    48961 acatataaag ctaaactata ccctatcata agacctaaaa atgtcatttt tctagttttc
    49021 attaagttaa ctcctccaaa ttttatctat catcttacat tataatacaa aatatataaa
    49081 aacacctaat ttagactaaa atatttttaa tctatttaga ataaatatta gttatttcaa
    49141 tgtgcaatta cctctataaa tcttgacttt ttgtatcata cttgttacaa ttttaatgat
    49201 aatgaatttc attaggaggt gttaataatg actgtttacg atttaaaaat aggagaaaaa
    49261 ggatttatta atagtataga tggagatatt aaattatcta aaagattgct tgcacttgga
    49321 tgtataaata gtactgaaat agaagttaaa aaggttgccc cacttggaga cccaattata
    49381 attagattta gaggctttga ccttgcgatt agaaaatctg atgctaaaaa tatttcttta
    49441 caataataga ggaggagcta cccgtgatta atgtagcatt attaggaaac ccaaatgtcg
    49501 gtaaaactac tgtttttaat ctacttacag gttcaaatca atatgtaggt aactggcctg
    49561 gtgttactat agaaaaaaaa gaaggatttc ttggaaaaga gataaaggtt gtcgatttac
    49621 ctggtatata tgcaatggat actttctcaa atgaagaaaa ggtttctaaa tcatatttag
    49681 aaaatgaaga tgttgatgta atagtaaatg tagttgatgc ttctaattta tcaagaaacc
    49741 tttacttaac aactcaactt atgcaattta acaagcctat agttatattg cttaatatgt
    49801 tagacattgc agaatctaaa ggagttaata tagatgccaa aaaattaagt gaagaacttg
    49861 gagtaattgt tgttccaatt atagcaaaaa agaaaaatgg tgttgatagg atagaagaag
    49921 agattaaggg agctacgcaa aaagctttta tatatcagaa aaactttgga agtgaaacag
    49981 aaacatataa aaaattagaa tccattttat cgagatgtac aaaaactaca tatacacaaa
    50041 agaaatctat cagtgataag atagacaata tagtcttgaa tcctatatta gcatatccga
    50101 tatttattgg tgtattgttc ctcttattta aatttacctt tgactgggtc ggaggaccac
    50161 tacaagaggg atttgctagt cttatagagg cttatatttc tgcacctgtt agtgatatgt
    50221 tatctaactc tagcccatgg tttaaatcac ttatagttga tggaataatt ggaggtgttg
    50281 gtggtacttt accattcttc cctttaatat ttacattatt ctttggtata tcgttgtttg
    50341 aagatagtgg atatatgtca agaacagcat ttttaatgga taaagttatg agaaaggttg
    50401 gtctatctgg taaagctttt atacctatag ttatgggtat gggatgttct tctccagcta
    50461 taatggcaac tagaacattg gaaagcgaaa aagatagaag agttacagct cttattgcac
    50521 cacttatgac ttgtggagca aagctaccta tatatgcact atttgtagct atattctttc
    50581 cacataatgc tgctttagta actacatcac tgtatttggt gggtatagtt atggcaattg
    50641 tagttgcatt attcttaaat aaaacagcct ttaaaacaga ggctgaacca tttatattag
    50701 aattaccaga atatagaatc cctactatag atgcacttat taaaaatact tggaataaat
    50761 caaaaggttt cttgataaga gttgttactg tcatgtttgc aatgtcagtc gtaatttggg
    50821 gactttcttc attcaatgtt tttggatata cagaagatat aaatgtaagc ttcttggcta
    50881 ctctaggtca tattatatct cctatattca aacctcttgg ttttgatgat tggagaactt
    50941 cagttgctat tttaagtggt cttggagcaa aagaaatcgt agtaaactct ttaaatatac
    51001 tatatggtaa tctaactgtt gtcttaccaa caatatttaa tggagttact gcatatacat
    51061 tcttgatatt tactgcttta tatactccat gtatagctgc acttgcaact atgaaaaaag
    51121 aatatggcaa taaaatgatg tttacatcat ttgcatatca atttatacta gcatggataa
    51181 tggcttttat agttaaaagt ataggtggag tactatttat gggtaattca ataatagaag
    51241 ctttgatagg tggaataatt atagtccttg cactctttat tctgtttaat aaattcaagt
    51301 ctacaaaaaa cggaaatgtc tgtagtggat gttctatttg ttctggatgt ccaagtgcta
    51361 attcttgctc aagtaaggaa gacagcaata aaaaaaataa tgcacactaa tatataaata
    51421 ttttagttta aaataagata aaagtgggtg tctcaaaatt aactttttag ttcatgaggc
    51481 actctttttt atagaaaatc aaatatattt tcatcatttc aacagtaaaa aagagcttat
    51541 ctagtaaaaa agaggcttat ctctattttg agacaacctc tttttttgtt acttattcag
    51601 tttcttgcta cctaacttca tgtggaacct agtatctttt ggaacacttg ggtctacacc
    51661 tcttaatgta ggtatttccc cacatattag ttgtataggt actataaaat taaatgtttg
    51721 atagtaagga ttatctgtga tatcaatctt taaattttta tcattttctg taacatctct
    51781 acctatagca aatacatttt ccgtccaacc agaaagtaca tcaatcatct tagttactct
    51841 aggttctttt cctgtatcta gtataaatat agtagaatca ctatttatag cattatatat
    51901 accatgtata aactcttcaa actcataccc agttacaggt attctcattg tttccaataa
    51961 ttttaatgct gcttctaatg tatctccata tatatcagag tgacctatta ttcttatttc
    52021 tttagaatta actaactttt ctttgtttct ttcaatccat tgtttagaga gcttatacac
    52081 tgcttcaaat ctattaattg cgtctaatat cttatttatt tcctcattgt acttttcact
    52141 agatattata cctttttctc tagctatttg aagacctaat aacattaagt ttaactttgt
    52201 acaataatat ccttttgttt tagctccaga tttttcttca ccacaattta ctgttaatat
    52261 ataatcagaa atctcatcta ttaaagcatt cttacaacct gccatagatg ctattttaca
    52321 gcccttatct tcagctaact tcatagcgtt gtatgtagaa taactactcc caccttgaga
    52381 tacacctact actagggtat tttcattatc aaacttgaat gtatcttcag ttatcataaa
    52441 tggatacatt ttcacaacat ctatatctaa taaattttgt aaatatggtt gtacttgcac
    52501 tcctgagtga tagctagtac ctgaacctgt tattataatc ttttttagat ttgttctctt
    52561 aacttcatta aataagctat ctgcattaga tataatttct ctcattctaa ctggtgtttc
    52621 taacatataa tcttgtattg tcattttata caccttcctt atctatatat tcaataaatt
    52681 ataattaatt tctataacaa acctatagca tgtaaagcga ttcctgttac tatagtgcct
    52741 atagttaatt ttgttacact tacctttctc tttaacatgt agtatattac aaatgcaaag
    52801 gttaaaggta acatattagg tattatttta tctagtatat cttgtaaaat tacttctgca
    52861 ccatttaagt tgaatttcag aggagtagtt atactcaaca tagttgcaac cattcctcct
    52921 acaacgaata aaccaacagt tgtagccata gacattattt tctccataag tccctctctt
    52981 tgtattcttt caagagaatt tacccctact tgataaccat acttaagtcc aaatattcta
    53041 agggcaaatg ctggtatatt gtataatagt aagaataata gtggtccaaa gatattacct
    53101 tcttttgcaa gtgatactcc tactcctgct gctataatcc taaatgttcc ccagaataat
    53161 gaatcaccaa ttcctgcaag aggtcccata agagctgttt taacagcact aattgaactt
    53221 tcatcaaatt ctggattatt agcattctct tcttccatag ctgctgttat acctaatata
    53281 gcaggaacta ctactgtcgt tgtattaaaa atctccaaat gcctttctat tgcttttgct
    53341 tgattttctt tcttattgta tagcttcttt attgcaggta acattgaata acagtaacct
    53401 aagttttgca ttctttcgta attaaatgca ccttgaagag caaatgaacg ccaaaacata
    53461 cttcttaatt ctttttttgt taatttattc aaagtcaatc tctccttccg ttaaagtatt
    53521 gattgctaat tgaggatttt gattattttc tttgttattg atataaaagt ttagtacaaa
    53581 tgctacacat actccaaata aagctatagc agttatatct aatccaccat aagatgctaa
    53641 caaaaaccct ataaagaaaa atacagacat cttttttgaa agtaacatat ccataagcaa
    53701 tgcaaaacct actgctggca acaatgttcc tgcaacaccc agtccgtcta atataacttt
    53761 aggtattgca tttatcaatg ctgtaacttt atcagcacca atcataattg ctaaaaaggt
    53821 tggaactgat gtacttaaaa agaataatat tactggcaac cacatcatta tggtaacttt
    53881 cttaaaatca gcttgtttag catagaaaac tgccttttga gaaaagtacg aatttattat
    53941 tctaactaat actccaagag attgtgctaa gactgctact ggtactgcta ctgctaaagc
    54001 aacttctgca ccattacctg ataatatagc aaaagctgta cctaatacac ctcctgttac
    54061 tacatctgga ggagtagctg cacctattcc tgcaattccc atccaaatta attcaagctg
    54121 tgcaccaatc ataattcctg attttatgtc tcctaaaact aatcctacta acatacctgt
    54181 aactattggc ctatcaagca tagattgacc aaatatacgc ccatctagta taccaactcc
    54241 tgctataata gctaacatag tagcttgtac taacatattg aacctccatt ttaacttagt
    54301 ttaatttaca ttaaattaca ttacattttt gattttgttt tgattttcta ataactcatt
    54361 tacataaaca attccatttt ttgcttcctc taatcctgat ttaactatta gttttgtatc
    54421 ctcctcaact aataaaagta tagataaaag cattggtaaa tttactcctg tcaataattc
    54481 aaatttgaac ccttgtaaaa gtaagtttgt acatatgttt gccacacttc caccaaaaac
    54541 atctgttaag acaacaaatt cttcactatc tttattattt gataatatac ttctaatttc
    54601 tttctcagca tcatctgctg atttatccgt tgtcatacaa aaatactcaa tattagttaa
    54661 tgaaccaatt attaatttac ttgtgtcaac aagctctctg gacaattctc catgtgttgc
    54721 aattagaaat tttttcattc tctttctcct aaattatttt attaaatctg atagttgttt
    54781 ctttttgtct ctaggtaaca ttctaaattc tatatcaatc cctaaatcac ctatttgttt
    54841 aaagttattt atatcatcat catcaacagc aactaaatct gtaagtttct tcttcccttc
    54901 ctcatatctt aatcctccta catttatttc ttttaatact cctcctgaat ttttagctac
    54961 aactaaagca tctttggtat tttttactaa cactaataca ttgcttttct ttgaagaagc
    55021 aaatttttct actatttctc cagattcctc tacccccctt atatataaag ttacattgct
    55081 aggtttcgct aagttcagtg acatagcttt catttggtca ttttttgctt catcatttgc
    55141 aactagtatt acatttatac ctagtgatgt tgcccatcca tatgcaacct gaccatgtat
    55201 caatctgtca tcaattctca tcaaagatac cattttcccc aaatcctcca tcatacatta
    55261 aaatttttat tgtttatact ctcatttatc tataaaagca aaaagtatgc caaatactgg
    55321 catacttttt taaatttcat tcacttattt tgtaatcttg tattttactg tggtagacca
    55381 tagataatat tataaatata tcctatctct gaaattggta tttgcacact ataactcttt
    55441 tctagcacac taaatgcatt ttttattagt tttacttcac tatgatggtt tttgattaac
    55501 aaatccatat cagtatactc ttcaatttca gtttgtctaa ctaatctttc aatcatacaa
    55561 cttaagtgaa catataaaga aatcttttta tcatttgaaa gttttttctt ttgaatattt
    55621 tctatagcat taattccttc ttctattctc tctattatct tttttgaatc taaaatagtt
    55681 agactatcta ttactctaat taatgaaaaa ttctttacaa tagaatcatt tatgttcttt
    55741 attttttcat tttctactac tctgctaaat attctaaaaa catcatcttc tccttttcct
    55801 gatattatat cctctaataa tataaaatct accccattca catttggatt ggcagttcct
    55861 actatagcca tcacatcata catttcaaaa actggttctt tatctcccat agaaacaaga
    55921 ctatcataat cataaggtat tattttgaca tcaactattc caattaaact ttcggaaagt
    55981 agatgttgga tttttatagc agtacctatc cctgtaaaac aagatgatat tatagcatat
    56041 tctttatttt tttgaggata atacaattgt atattaggtt tagtttcttc atccataatt
    56101 tctgcaatct cttcaatgtt tttaccttgc attaataaat ttcctacttc tagtgcagaa
    56161 atagtggata tttggtctat aaataacatt gggctattta tcttattctt taaatcttca
    56221 tatataagat taagagagcc catatcaaat aacacaatta aaccattctt tatcctatct
    56281 ccctctaggt atctagacat ttgttttgat acatccgcaa tagtagcatc tataggcata
    56341 tcaatagctg taaatatatt tttacccaac atccgattac atacattcgc catactactg
    56401 gcagtagcat atccatgtgc tataatagtc gcattaactt gattaaattt cattcttata
    56461 attgttgatt taataaatat aatcattatg attatatcta cattattaag atacatatcc
    56521 aatctattcg ttattaatgt tgatatttta cttattatag agtattcttt gtaactctct
    56581 ttttttaaat atattagtaa tttattttct aaagctttat actcatcaga caattgataa
    56641 gattcgtcct tcaaataaag ataagacgaa aatgccaata cattattccc atcatatttt
    56701 atattgttat taacttctaa atttctaaat atatcctgca ttatcgatat tataagctcc
    56761 ataagtacgt tattattttc atcattattt gaaaagacta aattgtccat tagtctaatc
    56821 attagattag aactcttttt actaaatttt tcctttgtta tttcattttt ttctagtcta
    56881 tcaaagtaat ctaaacattt tatgaaactt tgatagatta tatttctttt atttcttcca
    56941 tttgacattt caatactaaa ttgtttagga gaaaagataa tgcttttgct tttaccactt
    57001 tggaattgaa atatatctac attttctata taaagatttc taggaaggtc ttgaagagta
    57061 acaaaaatat ttccatttct tctttgattt tttgcataag ctcgtccaca tgcatatttt
    57121 attacatttt tacattcacc tatattcccc ttgaatttta tctttaaaat cgcatttaat
    57181 gtaatttgag ttatctctat aggcaaacca agtaccttac tttcttcata aataaaatgt
    57241 tctacaatct ttcttttttc aatagtccct ctttcttcta tattgggaac ataaatattt
    57301 atgggtattc ttcttaaaaa ggtttgtaaa aattcagata gactttctgt tgtagcaaat
    57361 attaatctta ccctagcttt tctaattact ccattctctc caatcctaga aaacgtacct
    57421 gtatccataa atgtaaataa cttttcctga ccttcactat ttaatctatg tacttcatct
    57481 aaaaataaaa caccaccatc tgattgttct attagacctg ctctagattc atttgctcca
    57541 gtatatgctc cttttacatg cccaaataat agactagaca ataactccaa attattataa
    57601 tactgcgcac agtttaacac attgtatgga gaattttttt ctaatacatt actgcttaca
    57661 ctatatttgt atattatctt ggctaaaaaa gtttttccta ctccactttc acctgtcagc
    57721 attattgtaa gtccgccatt tggataaagt acagcggttt ttatttgttc gattacttct
    57781 tttaagctat tatcatatcc tatgatacta ttaaacacag tctcttgctt taataattta
    57841 cactcatttt taagttcatc taaattttca taaatacttt tttttgtagg tcctactaca
    57901 tcatttattt tatttttagg taaaaaaata acaggtctac tgtttatctt tataagatta
    57961 tcagatttta ctaaatcatt taataatcta cttgattgag ttctacttaa attaaacttt
    58021 tttactatat cttctgttat tatgccactt tcttttttaa gttcatcaaa gttgttaaat
    58081 aatacacatt catttacaaa acttaaaatt tcatccctca tgttcaacct ccaatacaaa
    58141 tatcaataat actataatat tagtatatca tttatatatt tatgaaaaag ataattatat
    58201 tcctatcttg attctctttt gtaagtttgt aaaatcaaac tttttataag tataaaatct
    58261 agatttttta acataatctc aaggttctta tctttccata tatctgacat aga
//
LOCUS       DAEHWO010000015        56061 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEHWO010000015 DAEHWO010000000
VERSION     DAEHWO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.015"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            123..926
                     /locus_tag="KNP54_001189"
     CDS             123..926
                     /locus_tag="KNP54_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBF0892105.1"
                     /translation="MMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVLK
                     LLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIVP
                     TSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKLG
                     VIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCAI
                     IHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
     gene            complement(1025..1987)
                     /locus_tag="KNP54_001190"
     CDS             complement(1025..1987)
                     /locus_tag="KNP54_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBF0892106.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFAWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(2303..3253)
                     /gene="hpdA"
                     /locus_tag="KNP54_001191"
     CDS             complement(2303..3253)
                     /gene="hpdA"
                     /locus_tag="KNP54_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBF0892107.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSVENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(3246..3503)
                     /gene="hpdC"
                     /locus_tag="KNP54_001192"
     CDS             complement(3246..3503)
                     /gene="hpdC"
                     /locus_tag="KNP54_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBF0892108.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            complement(3507..6215)
                     /gene="hpdB"
                     /locus_tag="KNP54_001193"
     CDS             complement(3507..6215)
                     /gene="hpdB"
                     /locus_tag="KNP54_001193"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBF0892109.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            complement(6512..7528)
                     /gene="tsaD"
                     /locus_tag="KNP54_001194"
     CDS             complement(6512..7528)
                     /gene="tsaD"
                     /locus_tag="KNP54_001194"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBF0892110.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            complement(7534..8010)
                     /gene="rimI"
                     /locus_tag="KNP54_001195"
     CDS             complement(7534..8010)
                     /gene="rimI"
                     /locus_tag="KNP54_001195"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBF0892111.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            complement(8000..8716)
                     /gene="tsaB"
                     /locus_tag="KNP54_001196"
     CDS             complement(8000..8716)
                     /gene="tsaB"
                     /locus_tag="KNP54_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBF0892112.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            complement(8716..9168)
                     /gene="tsaE"
                     /locus_tag="KNP54_001197"
     CDS             complement(8716..9168)
                     /gene="tsaE"
                     /locus_tag="KNP54_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBF0892113.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            complement(9307..10347)
                     /locus_tag="KNP54_001198"
     CDS             complement(9307..10347)
                     /locus_tag="KNP54_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBF0892114.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            complement(10676..11281)
                     /locus_tag="KNP54_001199"
     CDS             complement(10676..11281)
                     /locus_tag="KNP54_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBF0892115.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     regulatory      complement(11406..11523)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(11583..12749)
                     /locus_tag="KNP54_001200"
     CDS             complement(11583..12749)
                     /locus_tag="KNP54_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0892116.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     gene            complement(12897..15038)
                     /locus_tag="KNP54_001201"
     CDS             complement(12897..15038)
                     /locus_tag="KNP54_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBF0892117.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            complement(15182..16289)
                     /gene="prfB"
                     /locus_tag="KNP54_001202"
     CDS             complement(join(15182..16213,16215..16289))
                     /gene="prfB"
                     /locus_tag="KNP54_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBF0892118.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            complement(16304..18979)
                     /gene="secA"
                     /locus_tag="KNP54_001203"
     CDS             complement(16304..18979)
                     /gene="secA"
                     /locus_tag="KNP54_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBF0892119.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            complement(19111..19662)
                     /gene="raiA"
                     /locus_tag="KNP54_001204"
     CDS             complement(19111..19662)
                     /gene="raiA"
                     /locus_tag="KNP54_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBF0892120.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQENYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            complement(20215..20889)
                     /locus_tag="KNP54_001205"
     CDS             complement(20215..20889)
                     /locus_tag="KNP54_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBF0892121.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            complement(20892..21944)
                     /locus_tag="KNP54_001206"
     CDS             complement(20892..21944)
                     /locus_tag="KNP54_001206"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBF0892122.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            complement(21993..22952)
                     /locus_tag="KNP54_001207"
     CDS             complement(21993..22952)
                     /locus_tag="KNP54_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBF0892123.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            complement(23045..23566)
                     /locus_tag="KNP54_001208"
     CDS             complement(23045..23566)
                     /locus_tag="KNP54_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBF0892124.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCYQ"
     gene            complement(23577..24911)
                     /gene="celB"
                     /locus_tag="KNP54_001209"
     CDS             complement(23577..24911)
                     /gene="celB"
                     /locus_tag="KNP54_001209"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBF0892125.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            complement(24950..25276)
                     /locus_tag="KNP54_001210"
     CDS             complement(24950..25276)
                     /locus_tag="KNP54_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0892126.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            complement(25300..25608)
                     /locus_tag="KNP54_001211"
     CDS             complement(25300..25608)
                     /locus_tag="KNP54_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBF0892127.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            complement(25749..27662)
                     /locus_tag="KNP54_001212"
     CDS             complement(25749..27662)
                     /locus_tag="KNP54_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0892128.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            complement(27994..28776)
                     /locus_tag="KNP54_001213"
     CDS             complement(27994..28776)
                     /locus_tag="KNP54_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBF0892129.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            complement(28779..30998)
                     /locus_tag="KNP54_001214"
     CDS             complement(28779..30998)
                     /locus_tag="KNP54_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBF0892130.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEENFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            complement(31262..32359)
                     /locus_tag="KNP54_001215"
     CDS             complement(31262..32359)
                     /locus_tag="KNP54_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892131.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            complement(32674..33867)
                     /locus_tag="KNP54_001216"
     CDS             complement(32674..33867)
                     /locus_tag="KNP54_001216"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBF0892132.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     regulatory      complement(34004..34107)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            34296..34805
                     /gene="yyaC"
                     /locus_tag="KNP54_001217"
     CDS             34296..34805
                     /gene="yyaC"
                     /locus_tag="KNP54_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBF0892133.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     gene            complement(34916..35344)
                     /gene="fabZ"
                     /locus_tag="KNP54_001218"
     CDS             complement(34916..35344)
                     /gene="fabZ"
                     /locus_tag="KNP54_001218"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBF0892134.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNITVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(35360..36379)
                     /locus_tag="KNP54_001219"
     CDS             complement(35360..36379)
                     /locus_tag="KNP54_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBF0892135.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            complement(36576..36836)
                     /gene="spoIIID"
                     /locus_tag="KNP54_001220"
     CDS             complement(36576..36836)
                     /gene="spoIIID"
                     /locus_tag="KNP54_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBF0892136.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            complement(36934..37602)
                     /locus_tag="KNP54_001221"
     CDS             complement(36934..37602)
                     /locus_tag="KNP54_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBF0892137.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            complement(37668..38732)
                     /gene="spoIID"
                     /locus_tag="KNP54_001222"
     CDS             complement(37668..38732)
                     /gene="spoIID"
                     /locus_tag="KNP54_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBF0892138.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            complement(38819..40072)
                     /gene="murA"
                     /locus_tag="KNP54_001223"
     CDS             complement(38819..40072)
                     /gene="murA"
                     /locus_tag="KNP54_001223"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBF0892139.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            complement(40093..40830)
                     /locus_tag="KNP54_001224"
     CDS             complement(40093..40830)
                     /locus_tag="KNP54_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBF0892140.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            complement(41286..42581)
                     /locus_tag="KNP54_001225"
     CDS             complement(41286..42581)
                     /locus_tag="KNP54_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBF0892141.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWREESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            complement(43032..44864)
                     /gene="glmS"
                     /locus_tag="KNP54_001226"
     CDS             complement(43032..44864)
                     /gene="glmS"
                     /locus_tag="KNP54_001226"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBF0892142.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            complement(45131..46477)
                     /locus_tag="KNP54_001227"
     CDS             complement(45131..46477)
                     /locus_tag="KNP54_001227"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBF0892143.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            complement(46647..47204)
                     /locus_tag="KNP54_001228"
     CDS             complement(46647..47204)
                     /locus_tag="KNP54_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBF0892144.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            complement(47205..47957)
                     /locus_tag="KNP54_001229"
     CDS             complement(47205..47957)
                     /locus_tag="KNP54_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBF0892145.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            complement(47957..49036)
                     /locus_tag="KNP54_001230"
     CDS             complement(47957..49036)
                     /locus_tag="KNP54_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBF0892146.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            complement(49065..49280)
                     /locus_tag="KNP54_001231"
     CDS             complement(49065..49280)
                     /locus_tag="KNP54_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0892147.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            complement(49323..50000)
                     /locus_tag="KNP54_001232"
     CDS             complement(49323..50000)
                     /locus_tag="KNP54_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0892148.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            complement(49990..51069)
                     /gene="buk"
                     /locus_tag="KNP54_001233"
     CDS             complement(49990..51069)
                     /gene="buk"
                     /locus_tag="KNP54_001233"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBF0892149.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLA
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            complement(51091..51993)
                     /gene="ptb"
                     /locus_tag="KNP54_001234"
     CDS             complement(51091..51993)
                     /gene="ptb"
                     /locus_tag="KNP54_001234"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBF0892150.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            complement(52297..53478)
                     /locus_tag="KNP54_001235"
     CDS             complement(52297..53478)
                     /locus_tag="KNP54_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892151.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESMEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            complement(53475..54314)
                     /locus_tag="KNP54_001236"
     CDS             complement(53475..54314)
                     /locus_tag="KNP54_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBF0892152.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            complement(55298..55371)
                     /locus_tag="KNP54_001237"
     tRNA            complement(55298..55371)
                     /locus_tag="KNP54_001237"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55335..55337),aa:Arg,seq:tct)
     gene            complement(55381..55455)
                     /locus_tag="KNP54_001238"
     tRNA            complement(55381..55455)
                     /locus_tag="KNP54_001238"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55421..55423),aa:Gly,seq:gcc)
     gene            complement(55466..55542)
                     /locus_tag="KNP54_001239"
     tRNA            complement(55466..55542)
                     /locus_tag="KNP54_001239"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55506..55508),aa:Asp,seq:gtc)
     gene            complement(55548..55623)
                     /locus_tag="KNP54_001240"
     tRNA            complement(55548..55623)
                     /locus_tag="KNP54_001240"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55588..55590),aa:Val,seq:tac)
     gene            complement(55629..55702)
                     /locus_tag="KNP54_001241"
     tRNA            complement(55629..55702)
                     /locus_tag="KNP54_001241"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55668..55670),aa:Gly,seq:tcc)
     gene            complement(55717..55791)
                     /locus_tag="KNP54_001242"
     tRNA            complement(55717..55791)
                     /locus_tag="KNP54_001242"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55756..55758),aa:Glu,seq:ttc)
     gene            complement(55799..55874)
                     /locus_tag="KNP54_001243"
     tRNA            complement(55799..55874)
                     /locus_tag="KNP54_001243"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55839..55841),aa:Met,seq:cat)
     gene            complement(55890..55975)
                     /locus_tag="KNP54_001244"
     tRNA            complement(55890..55975)
                     /locus_tag="KNP54_001244"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55939..55941),aa:Leu,seq:taa)
     gene            complement(55981..56055)
                     /locus_tag="KNP54_001245"
     tRNA            complement(55981..56055)
                     /locus_tag="KNP54_001245"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56021..56023),aa:Asn,seq:gtt)
BASE COUNT        16909 a        10622 c         6044 g        22486 t
ORIGIN      
        1 aaataaaaag aaaaaaaata caaattatta tctttttctt tataaacttt ggtttaactt
       61 attcattagg tttactgtta tattataata aatttattga tccagaaaac tttgcatcat
      121 tcatgatgat attacctcta tcttcagttg ccattgcaaa gttttatact gaaggattaa
      181 ataatgatat gtatgaattt tattcactaa tcatattatt ttttcttatt tattcattat
      241 taattgttct taagttatta aatctaataa ataataatga atttataatt ataaacctaa
      301 tattaacttt tataagtagc ttatcaatta taatatattc atcaaataaa aaaaatttat
      361 atcctgtaaa aaatattaaa ctaggttctt tattaattat ttactttatg atttctgtaa
      421 ttgttccaac atcatttata ctaatactac aaggggctca acctaattat agtggtatca
      481 taaaatttat atttactcca ataacatcat taactactat ttatattttt tttagtgaag
      541 aatatgcctg gagaggtttt ttacagaata ttttttttga taaatttggt aaaaagttag
      601 gagttataat attaggtatg tgttggagct tgtggcactt accactaata tttacattat
      661 atacacctga agcgccaata ttaggaataa tattacgttc aatacatata gttggaattt
      721 caatattttt aggatatctt tatataaaaa ctaagaatat ctggttttgt gctataattc
      781 atgttttaaa taatagtgct tttcttatca caaattctaa agaatcaact atcacttacc
      841 atgatatact aatagtatct atggttgttt taatttttta tgttccattt ctatttacaa
      901 aagaatataa aaataacttg gagtaaatag aatatccaag ttatttttat atttttgcaa
      961 atttccaaca atcctacaga atactttaag cttagaagat attattaaaa tttattataa
     1021 tcaactaatt cttgatattg gtcacattta ctttatcact aacaaaatca tacttagaat
     1081 ctctatagta ataccataca aatataaagc taagtagatt aacaaaagta gtcaaaattc
     1141 caccttcaat accaaacatt cctccattta atagattacc atgagtgatt tgtgtagtta
     1201 taatccctgg aacttgaagt ccacttacag gcataccata tataatcccc tgaaatacat
     1261 tccatgcaaa atgataacct atacacatcc atatattcga cgattttata aacatatatg
     1321 aaaaaagaat cccaataatt ataatattaa ttacagacaa aaaagtaaca tcaggattcc
     1381 atatatgaat caacccaaaa ataacagatg gaacaatcat tataaaataa atatttttac
     1441 atcttcgtaa aactgccata aaaaaaccac gatttaaaat ttcttctgca aaagcaacta
     1501 aaataaagac cagtatccaa gaaactgtta aaggtgaaat ttttggtacc catgaagtaa
     1561 catgaccacc accaattgtt attgttataa taaagattac tgtacaatta aatattccta
     1621 ataacattcc tacatatcct tcttttttct taattctata agaatgtaat cccatttcac
     1681 taataggatt tttcataata aatctccata caattatagg aataataatc ataagtgaat
     1741 ctgttagaat ttgaaataca atctgtaacc caacatcatt taaccaatta gcatattctg
     1801 aaaaatagtt tgtttttaaa ttaatgtcac ctgtagcaac caggattttt cttattattt
     1861 ccacaagtat catgcttaaa taatactgaa gtatgtaaaa ggtagccata acagctataa
     1921 taatccaccc tgaacgtact tttttgtctt tattcttaat aatcaagttg ctccatgatt
     1981 tgttcatata gatgtcttcc tcctaactat tatttttagt tgtttctaaa atatattcta
     2041 ttaaattttt tcatagtagt attttaccac aaaacttctg cttcaatgaa gtaagcgtaa
     2101 tatattctct aactgtaatt taaactataa aaaatatata aagtatattt aaagcaatat
     2161 ttatggacat aaagcaatat aaacaatata taaaacatat aaaactttac ttaattattt
     2221 ctacataaaa accacataaa aaaggatgta actctagctt ttagtgtaac atcctttttt
     2281 taattaaaac ttgtatttaa ttttagaaag ctgtctcatg accaacataa caagctatac
     2341 cattatccaa aaatatatct tgtaattctt caagatgacc ttcatcaaca tcacccttat
     2401 cagaatactc atattccttg cctaattgaa tccattttga ttctcctaat ctgtgaaatg
     2461 gtaatagatt aatttctacc aaattatttt tgtgcataaa agatataata tcacttatat
     2521 tttcaacact atcattaaac ccagagataa ctggtactct aagtactaat cttccattcc
     2581 aatcagaatt tgcaaggttt gatatatttt ctaatattaa atcattatac acacctgttt
     2641 gttctttgtg tttttctcta tccatatgct ttatatcaat aaatgcaaaa tcaatatcgt
     2701 taaatatttt attaaaaact tcatttgata cacatgcact cgtttcaatg gcagtgtgta
     2761 tatttacctc atgacacttt aataatactt catgtaaaaa ttcatgctga agtagtggct
     2821 cacctccact aaatgttact cctccattac ttctccaatt gttagaatca cgtttaatta
     2881 cctgcacaag ttcatctaca gtgtaaggtt ttgcacataa tttaaacgca ttataataac
     2941 atgagttgac gcattcaaaa ctttcacagt ccttacagat gttccaatct ataactggct
     3001 tattatcaag attaaagctc aatgcaccat ttttacactt accatgacat acagtacatc
     3061 cattttcata ttgacaagat aattcactaa acatcatatg tggtcttaca gtccaacttt
     3121 ctggatttgc acaccattta caactcagtg gacatccatt taaaaataca gttgttctac
     3181 aacctggacc atcatgaact gaaaagcttt gtacatcaaa aatcatgcct tctaattgct
     3241 tttgactact cattaaacac atgtccttca caagtaattg cattcaatgt tgaatatacc
     3301 cagtcttctt tctctaggcc aacacatttg cctatacctt catcattagc ttcaacaaaa
     3361 tttttacaat ttttacattt tggcattact tttatctctg gacatgctgc atcatctaaa
     3421 ttaatcattt gttttgataa tctacaaatt cctttggttg catctactgc acaaaaattc
     3481 atacaatcac tatgctttct catattttac accccttcat actctgttct agcaattact
     3541 tcatcttgta ttggtttacc taattcacac caatattgag taaacccagc aacacgtacc
     3601 attaattgac gataattgtc aggatttttt tgtgcatctt ttaatgtttc tgaatctaca
     3661 acattatatt gaatatggaa cccacctttt cttaaataac ttcttgttaa atctaataat
     3721 tttttagttc cttgttgtcc ttttatagta gttggatgaa gttttaaatt catctgagaa
     3781 ttttgaacta ctgcttggtc ccaaatagtt gcagattcaa ataatgcata tactccattt
     3841 ttatctgttc ctgcatatgc agagactgaa ccatctgaat atgttgttcc acttagtcta
     3901 ccatctggag tagccaaggt agcagctccc tgtggcccat gtgtagaaac agatatttgg
     3961 caagggtaca tcttcttagc atataaagat tgtgcttctt cacatacttt tgataaccat
     4021 acctcatagt ttttaagaat attatctgca tacaaatcat tatttccata tttaggtgca
     4081 tcaagacagg ccttataaat agcatcatat ttaccagtct tatctacttt tacttggtct
     4141 gccatagaat aatttcctac ttctaatgca tctttaaatc caaaattatt taatatggca
     4201 tccttcattt cctctattgt aaatgctttg tcatcatata caagtttctt aagtgctgca
     4261 aatgaattga ccatagtaac agtaccacaa gtttctacgt ttaatgttgc attataacga
     4321 tatcccatat ttcctatatg ttgacctttg tctaaacagt ctggctttag tagtgaattt
     4381 attatagaag tatcaaattt tctccatata tctaactcaa tgttatttgc tctttctaaa
     4441 acatttattg cttgtttata ataatcttta aatacttcta tgacttcttc ataagtatct
     4501 aatggcttat tatgaggctc aaatacttgt atattcatac gatagtcttt accattcata
     4561 agaacaagtt ctaaaatttt tggattagct ataaagtgaa ctccagagcc agcagattga
     4621 cctgctccac ctgcaataga gtatgttttt ccgtttaaag ttaactgttt ccaacaccct
     4681 ggagacgttt ccaaacatcc acctaatgca aatgctcttg cttcttcaac agtcatacct
     4741 tcatcagcaa attgtttcat cataaatgtt gttccatttg agttgtttac ccatgctgga
     4801 taaccagaac caagctttgt acattcagca gctttcatta agaaatcttc tggaagcttt
     4861 tcatcatata gcatagttaa actaggttga ggagttctac atctcatact tgcttctaat
     4921 aataactctt ctagttcatt agctcctgta gaaccatctt cttttaatcc acctatagat
     4981 aaagtattaa atgtattgcc tgatagtact cctccattta cgcccgctga agcaaaacag
     5041 tcaatacaag tgatttttat tctataaagc tctaataatt cgataacctc ttcttttgta
     5101 attagtcctt tttctatatc ttgttcatac caaggatata aaatttgacc aaaacgtcct
     5161 atagacatac cagatatagc atcctcattt actgatgcta tatgaattgt ataagtcaac
     5221 tgaagagctt ccctaaatgt acgaggttgt ttatgtgcaa tatgttctaa tatctccact
     5281 aaatctgagt attctttttt agcttctaaa tctgtctcta tactttctaa atattttgca
     5341 tgttttgcat aatttaaaat ccaagtttgt aatccttcaa taacttgaat aacagcctca
     5401 taaaaatata gacggtccat accaataagc ccatctccag atgcatttcc tgcaactgcc
     5461 tttttacatt cttttgccat ttctataatt ccatctaatc cataatttaa aggataaaaa
     5521 taatttataa cttctctacc ttgaggaagt gtataccctg aatcaaacat gcatataagt
     5581 gtactcatta ggttttcttt taaatcataa tctggcatca ttttttcata gtgaaaacct
     5641 aaatcttcaa cagactttcc aacccattcc tttgccattt ttacaagtac aggtacttct
     5701 tcttttctca ttccgaattt accagctatt gaaacgacat ttccaaaact ttcagtaaca
     5761 tttcctccac cagacccaaa ttttgtaagt tcatcagctg tgttactggc taatttcttt
     5821 gcctcttctc tcatttgttc tccttgagca acaaagaagc tttcacttac ccatggcatt
     5881 ggaaaagaac ctctataatg gcgtgtcttt tgcattacta ttttctcacc aggtattata
     5941 tttggtgtca tatgtgaaaa agcagcttta agagctttag ctcttctaac tactggtata
     6001 tcaccatctg attttctata ttctctatta taccaatatg gaaattccat atcagcagta
     6061 gataatgtat tataatatac atctaataag tcttctgctc ttttacttgc ttttttttca
     6121 ttaaattcac ttaaattttc tttattttga aaatttgatt taatattttt tgcttccaaa
     6181 atacttctta ttttgtcttc tttactttga ctcatttctt cccctcctta atctttctat
     6241 aattagtata aaacttttta agaatgaaaa aaaagggtat attacccact ttttaaaata
     6301 atctttctat agaaaaaaat aaacttgaag caaatctaag ccaaagacaa tctgtatatc
     6361 ctaaaatttg ttgcaattca ttggaatata aagattataa atagttttac ttcaagtttt
     6421 aatatatact atatttattt ttattatatt taatttcact tctacttact tttttgaaac
     6481 aatactttta tatttacaaa ttcatctaac tctactgatt tatctttaaa tttggaactg
     6541 catttaaact catatcatgc gttttcccat ttataaaatt ataatatcct gcacacccta
     6601 tcatagctgc attatctgtg cataaaatta gaggaggata cttaacagta ataccattgt
     6661 ctttagcaag ctctgttatt ttagctctaa gccccgaatt agaagcaacc ccaccagaaa
     6721 gagttatgat attgtatcct ttgtctttta ctgcttttag tgctttagta gataaaacct
     6781 ctactacagc ctcttggaaa gatgctgcta catcttcaac tactatttct tcatttttca
     6841 ttctttttcc atttagataa tttaatacag aagattttaa tccactaaaa ctaaaatcat
     6901 agctatcttc ttctaaatag gctcttggaa attctatagc atgtttattt ccattcttgg
     6961 ccagattatc aataatagga cctcctggat agcctaaatt catagctctt gaaatcttat
     7021 caaatgcttc tccagatgca tcatctcttg tttttcctaa aatttcatac ttgccataat
     7081 cttttacttc aaccaagtga gtatgacctc cagatactat taatgttata aaaggaggtt
     7141 ttaaatcctt atgctctata tagtttgcac ttagatgccc ttctatatga tttactccta
     7201 caagtggaat attcaaagta tatgcaagtg ctttagcata agatagacca accaataaag
     7261 cacctactag cccaggtcca tatgtaactg cgatatggtc tatatcatta aaacctatat
     7321 ttgctttgtc taaagcttct tgaacaacta tatcaatatt ttccacatgt tttcttgagg
     7381 ccacttctgg aactacacca ccaaattttt tatgtgtctc gatttgagta gagattatgt
     7441 ttgaaagtac ttctctacca ttttttaaaa ctgatgcagc tgtttcgtca caactactct
     7501 ctatagctaa tgttattata tcactcataa actctacacc tcttttaatt ggttccacat
     7561 tataattgca tcttctttat tatcactgta gtattctttt cttattccac ccattttaaa
     7621 tccatatttt ctatataaat tttgtgctat tttatttgat gctctaactt ctaatgtcat
     7681 agatgcaata ttattatctt tacataaatc aactatgcct tttatcaact tgtcccctat
     7741 ttttttccct ctatagtcac tatgaacagc cacattattt atatgccctt catcaagtat
     7801 aagccaaatt cccacatatc cgacaatttt tccatttaac ttagctacta tataccttgc
     7861 tacttcatta gacaactctt ttctaaaaga ctcttttgac caataatctt caaaacaatt
     7921 tttttctact tcaaaaactt catctatatc ttctgtagtc atttcttcta tttttatatc
     7981 atctactatt agttttgtat tatcttccat tatttagcct cttcattttt tcatcatatt
     8041 gtacttcagc ttgagatttt ctgatataca taggatttat cgtataacaa gtatgtacat
     8101 ctatattttt attatattta tttaatgcta aagagcataa gcttcctgcg ttagatacat
     8161 tattagctgg tgaaggtatt tttatatttt ttatattctc taacttgtct ttatatttgt
     8221 atacagcttc tccaactatt ataaattctt cattagttga tacaatttca tctactaaag
     8281 catcaaactc tacaacatca acaccatcta attctatcat ctctccattt tcaaacttgt
     8341 atttagctga ataaacttga tttttctgtg catctaatat acaacatatc tttctatcac
     8401 agaaatttat gttatttgct agagattcca aagaatttac tgctattatt ggtatattat
     8461 ttacatgggc catagctttt actgtagcca tacctattct aagtcctgta aacgaacctg
     8521 gacctataca tacagctaat aaatccatat cttttatact taaatcactc atactcaaca
     8581 tattttctat cattggcata agcttttgtg aatgagtttt tttgttgttt actgtaaact
     8641 cacatattaa gttatcatct tcaacaactg ctacacttgc tgccatagaa gacgtatcca
     8701 tacctagtat tttcattatt taatcaactc ctcaactatc tctttataaa actctccttt
     8761 tggagttaat atcatttctc ttccttcatc tttatatctc aattctatat tcaaatattc
     8821 ttttggaagt atatcttcta ttagattagc ccattctatt atacagattc catttgaatt
     8881 tacatattca tcataaccaa tatcatacat ttcatcacta ctacctattc tataaacatc
     8941 aaaatgatac aaaggtattt ttccttcata ttcatttatt atagtaaaag taggacttgt
     9001 tatataatct tctatcccta atgaatctgc caaactttgt gtcattgtag ttttaccagc
     9061 tcctaaatct cctactaaac agataacact gccttctttt aaaagtttac ctaatttata
     9121 tcctatttct ctagttttat tttcattttc taaatatatt tttgccatca attcatctcc
     9181 attttgatat aatcgtcatg tgaatttata tcactgctta attaattata gtataagcct
     9241 agattattat aaagtacttg tctttatctt tttttatctt tcactattga tggctgtatc
     9301 tacaccttat atacaatcat caatagcaat ttttacatac tcttttgctt tatggttttg
     9361 cttcaatgct tctttacata ttctctcaga ttgctctttt acatacttaa gagacttata
     9421 gttctctttt actgcttcaa tacacatttt ttctgtttga ttttttatat acataagcat
     9481 ttttccattt tgtcttacaa tctctataca tatatcttct gtatacttat ctatgtaact
     9541 tagtacatct ttaatattat attttttatt taaatatctt atagcattta tacatatttc
     9601 ttctgtctta ttgttgacaa attgtatact tcttccatct tgtttgacag cttctataca
     9661 tattttatca gtttgtttat ttacatattg taatgccata ccattttgtc ttacggattc
     9721 tatacacatt ttttccgttt gattttttac atattttaat gctttataat tttgcttaat
     9781 ggcctctata cataattctt cactctgttc tctaacgtat gcaagacacc tgccatcttt
     9841 tttaattgct tctaaacata tccttcttgt ttgagtctct aaagccttta gtatacttac
     9901 aacatctata ttggaagaat gacttattgc ttttataata agcccttctg ttttatttcg
     9961 tacatactta agtgcattac aatctttttt tatagcttca agacacaagt attctgtttg
    10021 ttcttttaca tattcaagtg ctttataatt atactttatt gcttctaaac ataattcttc
    10081 ggtttgattt tttacatact ctaatgcctt gtaattctgc cttattgcta aaatacacat
    10141 accatcagtt tgattttcta tattttttaa ttcacgataa tcgtatttta ccctttccat
    10201 attttcaata tattcattag tgatatactt taaagaatct cctaattttg tatcataaat
    10261 accaatatga atatctttcc aattactatt aaaataatac cctttatcat ctaaaaataa
    10321 tttttttatt tttttagata aatgcatgaa tatacacccc tatcattatt aaattagtta
    10381 ttattaaaag tttgattatt aatctttata gttttttaat aataacttta ttttttgttt
    10441 attataaatt cgctctgtat attgtagata cctttttcat attttaatag ttaatcgttt
    10501 taattcttcc tttattttaa aatttaaatt tgtctaaata tttcttattt tatatacatt
    10561 ttttgataaa ttaataaagc cataatatat ttaatatatc aatcacaata taggactgaa
    10621 gttataaata aattatggct attcaataca tttaatttta tattttcttg tctaattatt
    10681 tctttattat atttcccatt tttttataaa gtggcaatgt tactaaagat attataacag
    10741 ccttcagcac attaaatgga gctatcatcc aaattacaaa agtgaataaa tcatgaactt
    10801 gaggatttat agctgaacct aaacctatta tagcatctag tcccataagt tgaccataaa
    10861 gtggcaacat tacaaaataa tttactaatg aaccaattat agtcatagat attgttccta
    10921 atacaaaacc aatcagtaca ccttttaaat ctccacttct cttatatgaa taacaaagta
    10981 tcattacata agaaccacca attaatatat ttgcaaattc tcctattcct ccagttgttg
    11041 ttgctgttat tgcttgtaac acatttttta ctacaactat tccaaatcca actaatggtc
    11101 ctagagacat tcctccgaat attgctggaa tatctgataa gtcaattttt aagaaatctg
    11161 gaaatatacc tggtattggt gcttgaataa acattaataa ataagatatt gcagataaaa
    11221 ttgacattac tactaaagtt cttgttgaaa tcatattgcc tctttttgct gtgttttgca
    11281 taattatttt ccccctaatc aatatgttta tattttttag gaaaaacaaa aaactcgaag
    11341 accctatctt cgagttttta tggatatagt ttaaacaaac taaaataaac ttatttatct
    11401 tccataaata tcttctctca tccagacttt actgtcggct ttggaatctc accaaatcaa
    11461 ccacctaagt agttcgcggg ctataccgcc ggtagggaat ttcaccctgc cccgaagatc
    11521 ttctttgatt ttttaatttt ccttacactc ttatattagt taatttttta ataattgtca
    11581 agttattttt tctcatacac tactttgcca tttattatag tgtaaagtac attactttga
    11641 atctctagtg gagaattatc ccaaattact aggtctgcat ctttaccaac ttctatagag
    11701 cctactctat cttctattcc taaagcctta gctggattta tcgtaattga ttctattgct
    11761 ttttcttctt tcataccatg ttttactgca atacctgcac atattggaag atattgaact
    11821 ggtattactg gatggtctgt cattatacat acatcaagac ctgcatttga aagtattcct
    11881 gctgtattaa atgtcaaatt tctaagctca aatttagacc tttctgacaa agatggccct
    11941 actattacag gaaacccttc ttccactaat tcatctacaa taagatgacc ttctgtacaa
    12001 tggtctaatg taagctttaa attaaattct tttgcaattc ttattgctgt aaacatatca
    12061 tctgctctat gagcatgtgc cttaaaagga atttctcttc ttaaaactgg tattaaactt
    12121 tccattttta tatcatattc aggtttttca cagtcttcat catcatgact ctcatacata
    12181 tcaatatcct ctaaatattc ttctgctttt tttaggtttt ctctaagtaa agcagctata
    12241 gccattctag tttgaggaga tttatcatcc tgaccataac agctctttgg attttctcca
    12301 aaagcaattt tagatgcaac tggatttttt attaccattt tatcaattct ttttccacat
    12361 gtctttatag ctatacattg accacccata acatttgcac ttccaggggt tgtacaaaca
    12421 gaagttattc caccttcaaa agcttcttta aaagttctat ccattggatt aattccatct
    12481 ataggattta attgtggtgt tattgggtca gtctcttcat ttccatctgc tccttcaaac
    12541 cctataccat cttcccataa acctaagtga gtatgagcat ctataaatcc aggaaacaca
    12601 agtttattac tagcatctat tacctctaca tctaaaggag ctatcaaatc ttctccaatt
    12661 tctattattt ttccttcatc tataagtata tctccatgaa ttatcccatt tgttatggta
    12721 tttattttac cattttttat aaaaatcatt cattttcctc ctgattttca agactatcgt
    12781 tcttatttta atatattttc ttactatata cttttacaaa tttttaacat ttatacactc
    12841 gagtaatctt atttacaaat atagaatcta agtactataa ccatacataa acttatctat
    12901 tttttcattg ataaggcaac tctttttttg tttaagtcaa ttccaatgac ttttacatct
    12961 actatatcac ctactgtaac aatactcata gggtctttca caaaactatt actcatttct
    13021 gatttatgaa ctaatccgtc attttttatt ccaatatcta caaatgcacc aaagtctaca
    13081 acatttctta ttgtaccttt taaagtcata ccctcttgta tatcttcaat ttttaagaca
    13141 tcagttctaa gtataggttt tataccttct tctcttgggt ctcttcctgg ttttttgatt
    13201 tcagctatga tatcttttaa cgtaacttgt cctacttcca gtttttcact taattccctc
    13261 aagccaattt cttttatttt ttcatctatt tcacctatat tcttattctt tacatcatct
    13321 aaagaatatc caattatctc aatcattttt ttacatatat cataactttc aggatgcaca
    13381 cctgtattat ctagtggatt tttaccctct aagattctca taaatccagc acattgagta
    13441 aatgcttgag gtcctagtct ttttactttt ttcaattgtg ctcttgacgt aaaatctcca
    13501 ttttcttctc tatatgctat tatatttttt gctatagctt tacttattcc tgcaacatgt
    13561 tctagtaggg agtatgatgc agtatttaaa tctactccaa cactatttac agaatcttca
    13621 acaactccat ctagtacttc ttctaatctc tttttgttta aatcatgctg atattgacca
    13681 acaccaatac ttttagggtc tatttttaca agctctgcta atgggtcttg taatcttcta
    13741 gctatagata tagctcctct tattgataca tttatatctg gatgttcctc atttgcaagt
    13801 tcagatgctg aataaacaga tgctcctgct tcactaacta tcacatactg cacttcgcta
    13861 tctatttctt ttatcatttc tgatacaaaa gtttctgatt ctctagatgc agtaccattt
    13921 ccaattgaaa ttatatctat atcgtatttt tcaatcaatc cttttaaaac tttctttgct
    13981 ccctctacat cattttgagg gtctgttgga tatactgttg tataatctag tagtttacca
    14041 tttttatcta ctacagctat tttacatcca gttctaaatg cagggtcaaa tcccataact
    14101 actttgtctt taactggtgg ttgaagcaat aaacttttaa cattctttcc aaatacactt
    14161 atagctcttt cttgagctat ttctgttaaa tgatttctta tttctctttc tattgatggg
    14221 aaaattaatc ttttataaga atcttctatt gaacttacga tttcttcttt atttttgaaa
    14281 tttttatcat ttacatattc gtttattatg taatttaaaa ctttatcatt atttatttcc
    14341 aacttaacct ttaggaagct ttctttttct cctctgttta ttgccaaaac tctatgtgga
    14401 gccatacttt ttactgcttc gctataatca taatacatat cataaaccga tttctcatca
    14461 gtagcacttt tgctaactat cataccttct cttaaagcta attctcttat atactttcta
    14521 atcttagcat catctgagac tagttctgca attatatctc tagcaccttt tagagcatct
    14581 tcaatagaaa gaacttcttt ctcttcatca agataattct ttgcctctat ttctatatta
    14641 tctaaattat tctctagtat tgacaatgct aaattttcta atcctttttc ttttgctatt
    14701 gttgctctag ttcttttctt ttgtttatat ggagcatata tatcttctac ttcttgtaat
    14761 gtttttgctt tttctatatt ttgtgttatt tcatctgtta atttcccttg ttcatctatt
    14821 agtctaacta catcatcttt tctactttga agatttctca aatacattaa tttttcataa
    14881 aattctctta gtgtaacatc actcatttcg ccagtcattt cttttctata tctagctata
    14941 aatggtattg tatttccttc atcaataagt tttaatgtat tatttatttg ttcatctcta
    15001 agattaaact ctttttttaa gatttgattt atatccaatt tattcactcc taatgttagt
    15061 ttttcataag tataacaaaa cagaacgaag gctgagggtt atcgtcctca gcctaagtgc
    15121 tgtaagtgca tattaagcac taaccttctt atacatatat cttaattaca gtgcatattt
    15181 attaaactat tttattcatt tttaagtatt cattaataaa caagtctata tttccattca
    15241 ttacactatc tacatttcca aactcagcat ttgttctatg gtctttaacc aatttatatg
    15301 gttgaaaaac atatgaccta atttgactac cccaagttat ttgtgagtat ttgccttgta
    15361 tatcttctat tttttccttt tgctctaact cttttaattc tatcaatttc gccattaaaa
    15421 gtctcatagc tctgtcctta tttagatgct gagacctttc attttggcac tgaactacta
    15481 caccagtagg gatatgtgtt attctaactg ctgaatcagt cgtatttaca tgttgccctc
    15541 cagctccaga agctctatat gtgtctatct ttaaatctga tggattaatt tctacttcta
    15601 tattttcatc taactctggt gttacatcta tagatgcaaa tgaagtatgt ctttttcctg
    15661 atgggtcaaa tggagatatt ctcactaatc tatgaactcc tttttcactc tttaaatacc
    15721 cataagcatt tgttccttct acaagaattg tagctgtctt tatccctgct tcagggtctg
    15781 atattatatc taaaagctta actttataac ccttactttc tgaccatctt atatacattc
    15841 tcaaaagcat ttgagcccaa tcttgagcat ctaagccacc agtaccagca tttatagata
    15901 atatagcatt atttttatca tactctccat ttagaagagt ctttattttc atttcagata
    15961 atttttcttc cattgattct atggactttt ctatatctct ttctacagaa tcatcatctt
    16021 cttctaaacc tatttcaatt aatacttcta tatcttctaa taagcttttt aagctttcat
    16081 attcttctaa tgtctctttt aaagatttat tttcttgaag tactctttga gcgacttcat
    16141 tatcattcca aaaatcttgt tgattcatct tttcttcatt aatttgtata tttttcatca
    16201 atgaagctat gtcaaagaga aaccctcaat tcttctaaat ttgaagccat ctgctccata
    16261 ctatgtctat actcttgtaa ctttaacatt taatcctccg agattatctt ccacaacagt
    16321 ttttatattt tttaccactt ccacaagggc ataagtcatt tcttccaacc ttttcatctt
    16381 ttttaacagt tttacttgtt ggaagtgttc catctgatgg agaagataga ttttcaacat
    16441 ctacaactgc ttttctttcc actggagttt ctattgttat attaaataaa tatcttacag
    16501 tatcttcttt gatatgttta ttcatttcat caaacatatc aaaaccttcc attttataag
    16561 caataactgg gtcttgctga cctacagcac gaagaccaat accttggcgt aattggtcca
    16621 tagcatctat atggtctatc caatggttat caacagcttg aagtaagatt actctctcaa
    16681 cttctctcat tctctcatag ccaacttgtt cttcttttga agtatatatc ttcatagcta
    16741 tttcataaac tttttctgtt atttcaactg gattaagttt ttctatttct ggtatttcta
    16801 tgctaccttt tggcaagaac agattataca tatgttcttt gaatccttct tcatcaaatc
    16861 ctttatcttg tgtataaaga gtaactgctt cttctattat agaatgagtc attgattgta
    16921 tttgttcttg taaatcttca ccttctaata cacgttttct ctctgcatat attatttctc
    16981 tttgtttatt cataacatca tcatattgaa gtacatgctt tcttattcca aagtttttac
    17041 cttcgacttt cttttgtgct ccttcaatag acttagataa tattctatgt tctatcggca
    17101 tgtcttcttc aagacctatt ttatctacaa taccagatat tctatcacta ccaaacaatc
    17161 tcataaggtc atcatcaaga cctatataga atcttgaact ccctgggtca ccttgacgtc
    17221 cagcacgacc tctcaactgg ttatctattc ttcgagattc gtgtctttct gtacctatta
    17281 tagcaagtcc acctgcttct acaacttgtt tttgttcttc ttgtgtttgt tgcttaaact
    17341 tttcaaatag tttttcatac tcttctctag cttcaaatag aatttcatta ccttttacag
    17401 gtataccttc tattggagta tctactctat ttactatttc ttctttaaat ccatttcttc
    17461 tcatttctct cttagttaaa aagtctggat ttccacctag aactatatct gtaccacgac
    17521 cagccatatt agtagctatt gtaacagctc caagtctacc agcttgtgct attatttctg
    17581 cctctttatc atgatgctta gcatttaata cctcgtgctt tatgcccttt ttctttagta
    17641 tttgtgataa taattctgat ttttctattg atactgtacc tacaagtatt ggttgattga
    17701 ctttgtgcct ttcaattatt tcttgtgcta cagcattaaa tttacctatt tcacttttgt
    17761 atacacagtc tggtaagtct tcccttatca taagcttatt agtaggtact tggaaaacat
    17821 ccattttgta gattgcttta aactcttctt cttctgtttt tgctgtacca gtcatcccag
    17881 aaagtttttt gtacattcta aagtaatttt ggaatgttac agtagctagt gttttagatt
    17941 ctctttgtat tttaagacct tctttagcct ctattgcttg atgtaaacct tctgaatatc
    18001 ttctaccaaa cataagtcta cctgtgaact catctactat tactatttct ccatctttag
    18061 caacataatc aacatctttc ttcattatta catgtgctct taaagcttga tttatatgat
    18121 ggtataattc tgtatgagat atatctgtta tattatcaac attaaaatac acttctgctt
    18181 tttgtatacc cgatgctgtt agagatacag ccttatcttt ttcttctaat tcataatcat
    18241 ctggttttaa ggttaaaaca aatgtgtttg catctgaata taagtgagtt gatttgtctc
    18301 caggtccaga tatgataagt ggtgttctag cctcatctat tagtatagag tcaacctcat
    18361 ccactatagc ataatttaat cctctttgaa ctctttgctc tttgtgtatt accatattgt
    18421 cctttagata gtcaaatcca tattcattat ttgtaccata agttatatca caatcatatt
    18481 gttcttttct aacttttgga ttttgaccgt gtataataac gcctacactc attcctaaaa
    18541 actcatagat ttttgccatt tggtctctat cacgttttgc aaggtaatca tttactgtta
    18601 caacatgtac accttttcca gtaagcgcat tcaaataaac aggagcagtt gcaaccaaag
    18661 ttttaccttc acctgttttc atttctgcta ttcttccttg atgtagtact atacctccaa
    18721 tcatttgaac tctgtagtgt ctaagtccta acactctctt agaaacttct ctaactactg
    18781 caaaagcttc tggaagtata tcatctatac tttcaccatt tgctaatctt tctttaaata
    18841 tatttgtcat atttttaagt tccgagtctg ccatagattc aaatttaggt tctaatgaat
    18901 ctattatatc aacagtttta ttgaactttt ttaattcttt tttatctgcc atgttgaata
    18961 aattatccat aaagctcata ttttacatct ctcctcgttc tttattgtac tattattcat
    19021 tttaccataa aaactatact tttaatatta atttaaaaag ctatcgataa tttatttatc
    19081 gatagctaat atgattaaat ctaaattgct ttattcatgt tctattatac catatccacc
    19141 attattacgc ttataaacta ctgctatttc atctgaatct atgttcttga acatataaaa
    19201 atcatgtcct attaattcca tctgtaatac agcttcttct tcactcattg gcttaacact
    19261 aaatttctta cgtctttgaa ttactaattc ttgattttca tccccataat tctcttgttc
    19321 atcagctaga tttatctctg catcttggaa tcttatactc ttgttgtctt tatgtttatc
    19381 ttgtaatctc tttttatatt tttttaattg tttacttaat ttatcatata caacatctat
    19441 agctgtgtat aaattttcct gcatatcttc tgctctaatt ataggaccat ttacagtagc
    19501 tattgttact tctatttttt gtcttgcttt tctcgcactt actgtaactt ttacatcagt
    19561 gtctggatga atgtaattat ctaacttact tagtttagtt tcgattttat tttttattgc
    19621 atcagttaat tcgatttgtt ttccagatat aattatgttc ataaatacat ctcccttcaa
    19681 ttatgccagt ataagaaaat ttatacttta ataatatatt ctacacgaac tctcataatc
    19741 ctctttttat tatttacttt tatgattttt tctattcaat tgatagaatt atttatcatt
    19801 tttagttaca ttgatactta tgtggattaa tattattaca aacacctgtg gataatgtgg
    19861 ataaaactgt taataactct tgtttttgtt tatttaaagc tatttttact cctatttcta
    19921 tccacaaaaa tctccattaa ttgtttatta atatgtgaat tcatgtcata agatggtaat
    19981 tttaggaaat tatgtgtatt atatgccaat atacctttat aattttttaa taaatataaa
    20041 ccctctaaaa cctccataat ctatcttttc tttcattatt tatatttaaa actaattaaa
    20101 agttataaag catactcaac aataatttca tatttaatac ctattaacat tcatataccc
    20161 aaattataat taacttactc tctttattta aactaagtat tttatattca tatactatct
    20221 tgaaattata tttacgagtt gtttaagctt ttgtctatct atatcttcaa aaggactgtt
    20281 atttattcta atcgctgtac caaaatgaaa attacttgcc ttagttaatt cctttatctt
    20341 ttctatatta ttaaaattaa gacctccacc taaaagaatt tttatgtgat tagaactaag
    20401 catcatattc tttatcattt gtatgttatc aactatactt cctttccctc ctgatgttaa
    20461 tatattcgta attttatcat aatccttcaa aattttaaca ctatctattg tatttgattc
    20521 atctattgct ctatgaaatg taacatcaag attatcacaa catttcaata aaacatttag
    20581 atttttctca tctatactat tgtttttatc caatacacca aatacaactc cattagcacc
    20641 aatctcttta accacactta tatctttttg cattatactt atatcttctt tactgtatac
    20701 aaaacttttc gcatgatgtc ttatcattac gttcacaggt atctttacac tgttaacaac
    20761 actttctata agaccaaaac ttggtgtcaa tccaccttca gttaaagcac taactaactc
    20821 tattctatct gcaccacaat cttctataat tttagcgtct tctactgaca ttcctattat
    20881 ttctaacata actactcctt tgctaattca tatattgcat ttgcaaatat ctttgcattt
    20941 aatattatat cttctatatc catgtattca tcaggattat gagctattcc tttttgtcct
    21001 ggaaatgaag gtccaaacgg aactatattt ggcattactt ttgcatacgt acctccatta
    21061 gttgttacgg gagttccatc taatgatgta accctttcat aagctagctg aagcttttta
    21121 acaagattac tctctttatc aaaatataca ggattaaaat tagaaattac ctctatatcg
    21181 atactatttg gaaaactagc ttttatttca tccaatacat ctttcaattt ataactaaaa
    21241 tcgtatttta cctttatatc taatatagta tcactatttt ctatattcag ctctttatat
    21301 gtaacaagca cattttcaga catattttct ataaaaccta ggtatacatc ttcttcataa
    21361 ttgattttac tttttattct aatctttgcc atgccttttt caccatatac aacaggatat
    21421 ttacaatctg gtgtaaatcc cataataggt gctttttctt tttctaaata atatggtata
    21481 tcttcaaatc cactttcttc atttgtacca aatattattc taactctctt atctaatttt
    21541 aagtttaatt ctttaatagc atataatcca tataaggcag acattatagg tcctttattg
    21601 tctagtactc ctcgtccata aattcttcca ttagtttctt ctcccttata aggctgatgc
    21661 ttccaaccat ctccttcatg tacaacatct acatgtccaa ttacacaaac ataatcatca
    21721 ctatctccat gctctgcata accaatataa ttatccaagt ttctaacctt aaatcccaat
    21781 ttttctgata tttctaatgc tttattaagt gcctccccta ctttttcgcc aaaagggaag
    21841 ccattttctg actccccttt gacactaggt atttttacaa tatctataat atcacttaat
    21901 aaatcttctt ttaactcatc tattttatta cttatgatat tcataaaaat ctccttatta
    21961 taaaactcta ttttaattat gtaaccacta ctttactcac ttacttctat tggtgctttt
    22021 attctagcct catatgcttc catccactca tttgatataa ccttatgtat agtctttcca
    22081 tctactctat ttgaaatata tacagtagga gattcttctt tagttactac tgaaaaagta
    22141 aaatcagcta tatttgtagc tactccccat tcacctttat tattcatggc aactaatgat
    22201 aaatcaccag cttttcctct tcttttgata agctgtttat caagttcatt tactgcaata
    22261 tcacatgctt cttgtggatg cttcccttct ttcataagtc taactatctc ataagatata
    22321 catcccttca ttaaatcttc tcccaaacca gtagctgtag ctcctcctat actactatca
    22381 acatagaatc ctgaaccaga tagtgcagaa tctcctattc tacctctttt cttcataaac
    22441 aatccacttg ttgatgtagc tgcacacatt tttccagttt tgtctaaaga tatcatacca
    22501 acagtatcat gaccagcata tgggcttaat cctttgtcta aagtctcttt ttttctcttt
    22561 ttataatgta acttcgctct atcagtcaac atattttttc tttcaaatcc atttttatga
    22621 gcataatctt cagcacctat tccaactaaa aaattattta ccttctcata acttaacttc
    22681 ctagctatgc tgacaggatt agaataatct cttataccag caactgcgcc aatatctaat
    22741 gtgttaccat ccataaatgc agcgtcaagt tctacctcac aattttcatt tggaagtcca
    22801 ccatatccaa ccgatttata gaatggatag tcttcaactc ttcttacagc aagctctaca
    22861 gcatcacctg cttccatgcc tttttctaaa tgttctgatg cctcagttat tccttctagg
    22921 gccattctcc atgtcgctat cattccccac atgttaaaat tcccctcctt aaattatata
    22981 gattttacta atgtatgctt attataaata gtataatatt taaacttgct aataattaat
    23041 actcttattg ataacaaaac tcttctttca tcaaagttat atcttcttta tttgctattg
    23101 cttttgccaa tttacatatg ttatttaatg aatcattaag accaattcca cctttttttg
    23161 gagtcttaac tatacatatg tcatttttat attcgtttat cacatctata ttttcttctg
    23221 acatagctgc aaaagctggt atatctgttt tatcatttat atttttagac agtattgctg
    23281 acatcttaga aaagttttcg taattaaagc ttggtccaca gattactaca tcagggttta
    23341 atttttttac catagctatc atcttactcg ttacttcttc ttgattattt acaaaaaatt
    23401 catccccaca aaataaggta gctattacct tagattcatt taaaaattgc tccatcatta
    23461 cacctggtcc taatgggctt gattttccag caggaggtat attacttttc tcttttcctc
    23521 cagctccagc ttgtatttgg tccaatatca taactatttt cttcataatc ttcctcctat
    23581 aatactaaat catcaaaaga tatatcatca tcttcctctt caacagtttc attttcttct
    23641 ctcaagtatt gcttatctag catttttata aatggtatat acataaatat tcctagtata
    23701 agaagtacta attgtaagac tgcaccttgc catcctgttg ttaaaaaacc agagaatata
    23761 attggagttg tccacggtaa ctgaactcca tttgtaagag gcactaatcc tgctgacata
    23821 cagaagtaag ctattattat atttattgtt ggaactattg caaatggtat caatagtatt
    23881 gggttaagca ttattggtag accaaatatc aatggctcat ttataccaaa tattcctggt
    23941 aaaattgata gttttcccat tgactttata cgtttacttt tacatattaa taacatagct
    24001 atgactaatg atagtgtact acctgctcca ccaaatgtcg caaacatatc ttggaattga
    24061 cctgttatta tgtttggtat ttttgaacca gcttgaaaag cagctaagtt ttcagctgat
    24121 agaattttta atattggatt atacacagcc ccaacaacac tacttccatt tattccaaag
    24181 aaccagaata aatgtaagaa tatataagcg attgccatag cacctaaact atttcctaat
    24241 tttaataatg gcatttgtaa aaacttaaat ataaattcat gtatacttcc atatggtgta
    24301 gcttcaaaag ctatcttaac taaaaagaaa actaccataa ctattgcact tggtattaat
    24361 gctgcaaatg attttgatac agttggagga actccatctg gcattttcaa tgtccatcct
    24421 ttttttacaa ctgcagcaaa taattttaca gaggttattg ctgttatcat acctacaaac
    24481 attcccttag aacccatcca acctagtggt atacctgtta ccatgtaaac tgattctgtt
    24541 ccttctggtg tatatggtat tacaaatggt gttattataa aaaaggcaac tattgcaact
    24601 gctgctgatg ctattgggtc tacatctatt tgctttgcat aagaatatcc aatccctaaa
    24661 actgcaagta gagtcattac ttcaaatgtt gctacagttg gttgttgcaa ttttacagcc
    24721 caatctggac caaaaatttg acctacaaat tcattccatc cttttatagg aaaatttgct
    24781 actaataaaa ataatgaacc tattattaat aatggtgatg atactaaaaa accatctcta
    24841 attgcaatta ataatttatt tttacctatt ttttcagcca atggcataag tattctttcc
    24901 aatctattca tctatccacc ctcatttcct attatttttt actataattc tacgcttgtt
    24961 tagattttat tagctttata gcaagtttta atactttttc cccattcata gttccataat
    25021 caacttcatt gattatatct ataagttttc cttgagcttc aaactttggt tttaactcct
    25081 ttagcatgta tttaacttgt ggtcctaata atatacaatc tggatttttt tcttcaacta
    25141 ttttgtcaat ttctgctatc ggaaatgcct ctacttctat tggtaaattg tgttcatctg
    25201 ctaccttctg cattttatct gcaagtaaac ttgttgacat accaaagcta caaaataaat
    25261 atacttttct tttcattttt taaatccccc ttaatttttt tattttaatt tttgaatttc
    25321 ttttcttaac ataatcattt cttttataag gtttctctca ctcatacaag tcattaaatg
    25381 gtcttgagag tgaatcaata aaatagatat atctgattta tctcccccag cttccttttg
    25441 tataagttca gtttgtactt tatgtgcttt taaaatttct tcatttgcat tttcaattaa
    25501 ttcatctgct tttttaaaat cgttttcctt tgcatagtca agtgcttcat aaagcataga
    25561 ttttgcattt ccagcatgaa ttataatctt taaaactatt tcttccattt tttcctccta
    25621 agttgcttct ctacttttag attatttata ccttacaaac atataatatc ttataaaaac
    25681 aaaaaaacat gcacaacttt ttccatcaca tggaaaattt tgtgcttatc catagttcac
    25741 tatgaatttt atataagaat atcttttacc ttttcaatgt cacatttact tagaatatct
    25801 agcatatttt catcctctgt taaattagat atttctttaa ataattctct aaatactttt
    25861 ctatcatcat cttttttata cgctaacaaa agtataatct ttatatcctt tccatttcta
    25921 atttttattg gtgtttttaa ccttgcaaaa cataaaacag attgttttat atatttcatg
    25981 tctccatgag ggaataatat tccttttcca acattggttg gatatgactt ttctcttgtt
    26041 ataatagatt gtaaatactc tttttctgca taatgttttt caattaataa attagttaaa
    26101 tatgttatag cttcataaat atcatcatgt tctaactctc ttattaaata atcagacatc
    26161 attaatctgt tcataagttt atatgaagtg tctttttctt ttattttgtt tgtgaactct
    26221 ttaagtttat tctcatcctc atcagtaaat aatggtgttg ttataaaaat tggtttttgg
    26281 atattttcat actcttgaaa tgcaattata aaatctatag tcttattaaa gttatctctt
    26341 tttaaatctt cctctcttaa tgtttcaata atttttatgt tatcaaatct cttttctatc
    26401 tttactttta atagcatact tactccaaaa ctaaatggac atacaatact tgccttttta
    26461 tttgattccc ttttgctgta ttttctttct agagaggttt gaaagtgaag tgtaagataa
    26521 ccaatttcat cttccgttat ttgttttcct tttaattcaa tttctattga acttgatatt
    26581 actgtaaata aaaaacaaaa tttagttttt atgttatcta aaagtggatt ttctaagtaa
    26641 acattgcttt tcatttgatg cattgtaaca ttcaaatgac atattaattg ttcataaagt
    26701 aatatatcat tattaaaatt tattcctgat tcttctgata ctaaatttat aatttttttt
    26761 gtataacttg ctaattcttc atttagatat aaagatttct taatattatt actatttatt
    26821 tgtttgttca tacccaatat taaagattct ataaacaatt tttcttcata atttaatact
    26881 atggataaat tagatttcaa ttcatcttct atatccaata taagcatttt tagcttaagc
    26941 tctttcttag tatttgatac ttttaaagaa tttcccagcc ttattcgtat tatatttata
    27001 agcaaaaata gcatcaattg cttgaatgat atatctgtaa gtcttatatc catatcctct
    27061 tctatagtaa gcattatgtt ttttacaatt attatatcta ctatatggaa gtactctatt
    27121 tcatctatgt ttaatctgta tttatctata tatttaaata agaatgatac taacattatt
    27181 cttatgtctt tctcatcccc ttcaatatat ataccactgc cttttttagt cgagatattt
    27241 aaattataat tatttaatgc tactgataat ttacttattt cttctctgac aatattttta
    27301 tttatgtaca acttattaga taaatcattt aaagtaactt ttttattatt acaaagtagt
    27361 aaatttagta tctcaacttg cttatgaagc tcactattta ctcttttaac ttcacctcgc
    27421 aacttctgat ttaccagtat tttgtctgtt ccatctccac taaatttaat cccaatatta
    27481 ggttttcttt tgatataagc attacaaaaa gtagataacc attcatcaat atatttgcaa
    27541 tcatttctta ttgtcctttc tgaacactca aaatcattgg caatcttatt aacatttata
    27601 aactcttctt ttaatagcaa tgttgttaat aaattttctt gtcttttatt caaacatatc
    27661 acctctttat gactcaacct aaatttatta tatataaaaa agagctatac ataaaggtat
    27721 gctagctctc ttttaatatg atatttagct gacctggttt ttgaccccac actcgcctac
    27781 tggagggttc gcttgggttc gccgcactac tactctctct cgattttatt atcggtaggt
    27841 cttacttcta agccgcacca tgatcattaa cccaattttt agtgttaact tacgtggatc
    27901 cctttgcctg cgactggctt ggactttcaa ccacagacct aaatatcact tattcatttt
    27961 aatattttaa actaaaattg tcaatatata agattattcc ataatataat tatcatttgc
    28021 ttttgtaagt agagtcaata caaaaacctt attagcacct gataacttta aaagtttaga
    28081 aatttcgttt gttgttagac cagtagtaaa tatatcatct attaaaagta tatttttatt
    28141 atttattaat ttaacatttt ctttaacaac aaatacattt tttaattctt cttttcgttc
    28201 tttcttattc aatttatata gcattcttgt atattttttt ctacttatgc aatctaataa
    28261 tggaatattt actattttac ttaaattaaa tgctattttt tgtgcctgat taaaacctct
    28321 tttatttagc ctttttttat gaagtggaac aaataatata taatcaaatt ttatgttttc
    28381 taaatataat ttttctttca ttatttgagc tatatactta gccataaagg ttttttggtt
    28441 atacttcagc cctaacacca tcttttttgt cacatcattg tattcaatac aagatattga
    28501 tttatcaaaa taaaagtctt tattaaaaca ataactacac tcttcaataa attctttttc
    28561 aattgaatga cgtattattg gttttccaca cttcatgcaa ccatcttgta taaaattcat
    28621 ttctttaaaa caacttttac atattgaata agtatttgtt ttctttatgg atttatcaca
    28681 aattatgcaa cttatattct caggatatat aaaatccaaa catttattaa tcatattttt
    28741 aaaattctta ataaaattat cattgcatat tttcatattt attctatcaa caacccttct
    28801 tgtttaaatt tatttagctt atatcctaaa tttgaatacc tttgattaac tctattattt
    28861 tttatcatat attcaagata tttcacatct ccaactaata caactaattt ttttgctctt
    28921 gttactgctg tatataataa attacggcta agtaacatag gaggagccca cgctattggc
    28981 aatactacaa ctggaaattc acttccctgg cttttatgta ttgttgtaca aaaactatga
    29041 tcaatttcat ctaattcatc atataggtat gatacaattt tagtctggtc aaataatata
    29101 taaatagttt tcttatcttt atctatgtga taaacatatc ctatatctcc attatagata
    29161 ccttctccac tttctttttg gtcttctgtt tcccattttt ttgtataatt attttttact
    29221 tgcattacct tatcgccaac tctaaataat cttttagaaa aattttcttc aactttaaat
    29281 ttttcttttt tgttaagata cttctgtaac tctatattta gattagtaac tcccaattca
    29341 ccttttctca ttgaagataa aacttgtata tcttttaatt tatcaacttt ataaaattta
    29401 ggtaatcttt cattaaccaa tcctattatt tcatttaaaa tttcttcatt agttgatttt
    29461 cttataaaaa agaaatcttt accttttgta tttagataaa gtggttctcc attgtttatc
    29521 ttatgggcat ttacaattat catactttct tgcgcttgtc taaatatttc atttaattta
    29581 actacattta tgatattaga attaatcata tccttaagta catttccagc acctacagaa
    29641 ggtaattggt cactatctcc aactaaaatt actcttgttc ctaactttat agctctaagt
    29701 aaattgtaca ttaagataat gtctaccatt gatacctcat caacaattat tacatctgaa
    29761 tttattgggt cttcttcatc cttaaaaaaa gttaaatcat catctgttga aaatcccatt
    29821 tctagcaacc tatgtatagt ttttgcttct ttattagaag tttcactcat tctctttgct
    29881 gctcttcccg ttggagctgc cagagtcaca cttttaccat tattttcaaa tatatctatg
    29941 atagcattaa tggtagttgt tttaccagtt cctggtccac cagttataat taatactcca
    30001 ctattaacag attctttgac tgctaaaatt tgtttttctg ctaacttaat tttcttatct
    30061 tcttctaaaa cattaatctc gttatctata tctattttta agtcttcaaa ttcatactgt
    30121 gataatttta ctatttgact acatactcca ttttcagcta aatagtatgg cataaggtat
    30181 ataagatttt cattgtttac tttctctata tgtatttttt gattataaac tagcatcatt
    30241 acacactctt ttattatttc tccatttagc tccaataatt tttccgaatc ttgtattaga
    30301 acatgctctg gtaaatatgt atgcccatta cttaaagatt tatttaaagt gtataagatt
    30361 ccctgacaaa ttctatcttt agagttttta tctataccaa ttttacttgc tatactatca
    30421 gctactttaa atccaattcc tcttatatct tcagcaagtt ggtatgggtt tttatttata
    30481 acttctattg cactgctttt atatttttta tatattttta ggcagtaatt tggtgttatt
    30541 ccaaaaggag atagctgtat tattatattt ctcaattctc tgtcttcttc ataacttttt
    30601 actatttgtt ttactttttt actccctata ccttctactt cttgtagttt ttctggtgaa
    30661 ttttgtatca cctctaacgt atctacacca aacttatcaa ttattctttt tgccattttt
    30721 tcaccaatac catgtatcat tccagaagat aagtaaacat aaattccttc taaggatgat
    30781 ggtgttactg gcataaaact attcacttca aattgagtcc cataaatctt atgatttacc
    30841 cactttcctt caacttctat gctttctcca attgctaaag taggcataca tcctacaacc
    30901 acaatttcat cattttcatt taccaggtga gctattgtat aaccattatc ttcgttttta
    30961 aagactattt cacttatcat tccttctaat ttttccattt ttatctccta aaaatactaa
    31021 taatcgctcc atttaaatgt tagtataatt ttatatatta aaactatgat aatcgtagaa
    31081 aagttttata tttttatact taacgtaatt tccaactatt atacatttta tcagaaacaa
    31141 aaaaaatctg catccataaa atatggtacc atgaaataca ggtaccatat ttaaatagct
    31201 attttatttt aattactcta tatttagagt ataaattaaa tttcataagt atattacagt
    31261 actaacttat ttcagattta ttctccttgt acccctcagt tttagtaatt cttctataaa
    31321 gcatacatag taaaattaaa attcccatgt aacctgtata tggatatagt gtacctacta
    31381 acttatcaaa tggcagtaaa cctcctatac aagctaatat acttaccact attgttataa
    31441 ttttaaactt agggtggtca tcttctacaa atcggtttgt tactgaccat aacaatggta
    31501 cagctgtagt gtatattcct agtaaaagta ctactgagaa taaaatacct attattggag
    31561 atatcttatc agctaagtaa agtgctggta tctcttttgt gtatatattt cctatgtctg
    31621 aaagtaatgc caaattcatc attatagctg ctgccataag tgctactcca cctactatac
    31681 caccccatac agcatctttc ttatttactg cagaagctcc cattcctgtc aagaatgtta
    31741 ttactattat tacattgtaa caagtataaa gtactcccga gaaatatcca tttgatgtag
    31801 cagttttaat atttaaacta tcaaccatat ttccagcatt tgataaagca tcaatattgc
    31861 taaataaact aattgctcct actaaaagtg taaatattat tattataggt cctatattac
    31921 ctagtatttt agaaagcctt gtcaaaccta atgaaacagt tattagggaa acgattgcca
    31981 taccaatcct acctacatat ggatttaatc catagtactc tgataatgta gctcctgctc
    32041 ctgcaatcat tattactaat gttccaaata aaaacaatgg accaaaccat tcaaaaaatg
    32101 ttccaagata ttttccacaa tatacttgat aaatttttat tggctcctta agtttcaatt
    32161 ctcttccctt atctataact tctgctccaa accatgaaaa tagtaccata gagattattc
    32221 cacctataat acccgcatat ccataaaacg taaaaaattg cagtatttct tgaccagttg
    32281 caaatccaga acctattaca gtagcaacat aagctccagc aaaacttata accgttttaa
    32341 tatttacttt gcctgacata cactactccc cccaattaaa attattttta aagtgtaagt
    32401 ttattaagat tatattagac tcattattgt gatatttcaa tatattttta attatttaac
    32461 attagttaac acattcttaa ccatccttta acatatatcc cataatatgt ataaatttag
    32521 tagagtatta tataaaatgt attgaccaga ttaaatactg tttattcatt atatgatgat
    32581 aaattaacat ttattaaaaa tatttaactc ataataaaaa agctgttaga aagtaatcgt
    32641 aaaattacat tctaacagct ttttagttaa aaattattca cctaaagcat cttttcttaa
    32701 ctgctcaacc ttgtcagttc tttcccaagg taaatctata tcagttctac caaagtgacc
    32761 ataagcagca acctttttat aaagaggctt tcttaaatct aagtctctta ttatcgctcc
    32821 cggtcttaaa tcaaagtgtt tatttactaa ttcaacaagt ttttcttctg aaaccttgcc
    32881 tgtcccaaaa gtatctataa atatagataa tggtctagct atacctatag catatgcaag
    32941 ttctatctca catttgtctg caagaccagc cgcaacaata ttttttgcaa catatctagc
    33001 tgcgtaagca gcagatctat caacttttgt agggtctttt cctgagaaag ctcctccacc
    33061 atgtctagaa tatccaccat aagtatctat tattattttt cttcctgtaa gacctgtatc
    33121 tccttgtggt cctcctataa cgaatcttcc tgttggattt atataaattt tagtctcttc
    33181 atcaagtaat tctgctggta taacttcctt aataacatga ttaattaaat cttctcttat
    33241 tttatcattt gatactgttt cacaatgttg agctgatata agaactgtat gtactcttac
    33301 agctttactt ccttcatatt caacagtaac ttgagttttt ccatctggtc ttaaataatc
    33361 aactaaacct gtttttctaa cttctgtaag tcttcttgat aatttatgtg ccaaagatat
    33421 cggaagtggc attaattctg gagtctcatt acatgcaaat ccaaacatta taccttggtc
    33481 tccagctcca actttttcta tttcttcttc tatctcttct ccagtcttac tttctagacc
    33541 ctcatcaact cccatagcta tatctccaga ttgttcatca atagaagtta taactgcgca
    33601 agtatcacaa tcaaatccat attttgctct tgtatatcca atttctctta ctgtttctct
    33661 tactaattta ggaatgtcta cataagcaga tgtacttatt tctcctgcta ctaaaactaa
    33721 accagtagta actgtagttt cacaagctac tctagattgt gggtcttttt ctaataatgc
    33781 atctaatatt gaatctgata tttggtcaca tatcttatca ggatgtcctt ctgtaactga
    33841 ttctgacgta aataaatgtc ttgccatttt tattccccct tatttattct taatttttat
    33901 tataggtttt accttgtttt taattttaga aatttactca aaataaaaaa acctctcctt
    33961 tataagaaga ggttaataat cgtaattaca tactaattaa ctgacctcat ctttcaagac
    34021 ttttgtcttg taggaattag caccttttcc catttgggtg gttgctgggc ttcacagggc
    34081 ctatccctca gcctctcttg ataaggtaat caagatttaa gttttgtttt actttactag
    34141 cttactattt ttttaaaatt ttgtcaatat ttttagtcat attttttcta ttcctttttt
    34201 tgtaagacaa ataaaatttt ctatctatct gaaatttaaa gttaggtctt tttaatgctt
    34261 tttattcata tatttttttg aagggggtgt tcctattgta tttagctaaa gtaaactaca
    34321 gcgatgatga tgttatacag atgctaagtt cagttctaaa aactataatt aatgaaaata
    34381 cgattgttgt ttgcatagga acagacaggg ctataggtga tactttaggc cctttagttg
    34441 gaacaatact taagaacagt aactttaaat accccgttta cggtacacta gataacccta
    34501 ttcacgcctt aaatatatat gagtctttag atactataaa aaatacacat atacaaggta
    34561 acttcttggc tatagatgct tgcttggggt cgcagagtaa cataggtaat atacagatta
    34621 gagaaggacc tatcctgccc ggaaaaggtg ttggtaaaaa actacctcaa ataggaaatt
    34681 attctatagt aggaattgta gataaaattg atgaaaataa taaactttca tttaataata
    34741 tacgccttag ctttatatta gatttagctg aaacaatagc cttggcttta ttagtatcca
    34801 cctaatctaa atataaacta aatgataaaa ttctttatat aaaaaggtag atattttaga
    34861 gtatctgatt aaatactcca aattatctac ctttttactt ttatatttca agtttttatt
    34921 tttctactaa agcaaacatt aattcacctt tacagacaag ttcttcacct acatatgcct
    34981 tagcatctgc cttagctata ttttttctaa gagttgtcat ttcaacttcc atagttaatg
    35041 tatctcctgg tcttacttct ctcttgattc taactttatc tatacctgca aatacaccta
    35101 gttttccttt gttttcctct acagacatca ttgccactcc acatacttgt gctagagctt
    35161 ctactattag tactcctggc atcaaaggat attctggaaa gtgaccttgg aaaaatggtt
    35221 cattaactgt tatattcttt ataccaacag ctcttttccc aacttctagc tctgtaatct
    35281 tgtctactaa taaaaatgga tatctatgtg gtattaattt ttttatttca tctatattta
    35341 acattctaaa ctctcctaat tattttcttt tgaaagaccc accagtttca agtaagtcta
    35401 ttgaacctaa agctattcct gtaccttttg caacacaaga taatggttca tctgctattg
    35461 taacagttat tcctgtcctc tgttctatta ttttatctaa tccatataat aatgaacctc
    35521 ctccagtcat tattataccg acatctccta tatctgctgc taactcagga ggcgtttttt
    35581 ccaaaacagc atgagtagca actactattt gctcaacaca ttctctaagt gcttccaaca
    35641 tttctgttga atttatagtt atagaactag gaagtcctgt aattaaattt cttcctgtta
    35701 tcttcatata tttttcttct tctctcttaa atgcagaacc tatttcaaac ttgattttct
    35761 ctgctgttct ttctcctata agaagattgt gttgtttttt catatattta actatagcat
    35821 catcaaatct atctccacca acctttatag attcacttac aacagctcct cctagagata
    35881 ttacagctat atctacagta cctccaccaa tatctataat catattacca ttaggctgtg
    35941 atatgtctac accagctcct atggcagctg ctattggttc ttctatgata tatacttctc
    36001 tagctccagc ttgtctcgta gcatcttcta ctgctctttt ttccacttct gtgacacctg
    36061 ttggtacgca taccataatt cttggcataa aaaatcttcc aaatcccttt ttatcaacta
    36121 tcttatctat aaaagatttt aacatcttct cagttacatc ataatctgaa attacaccat
    36181 ctcttaaagg tcttatagcg actatattac ctggtgttct ccctatcatc tttttagctt
    36241 cttctcccac agctaaaaca gaatctgttc ttttgtctat cgccacaaca gatggttctt
    36301 ctaaaacgat tcccttacca ctaacataaa caagcacatt tgcagtacct aaatctatgc
    36361 ctatatcagc tccagccatt ttttcaactc ctttatttat aatattagat tatattataa
    36421 gcctatttta atactcctat aataaagcat atacaaaaat ctcgctttaa tcaagagaaa
    36481 ataaatcttt tgagagtatt attattttgc tatttataat tacttaatat atttcttttt
    36541 ataatttaat tcaataaaaa aagtaggttt ttaacctaca tttttttatg ttccttctca
    36601 tattttaatt tcgttgctaa tccccctcta atatgtctct ctgatttatt tttgtccagc
    36661 acatttttaa cttctttggc aagggatgga tttatttcct tcaatctttc tgtaacatcc
    36721 ttatgaattg tacttttact tactccaaat gtcttggcgg tttgtcttac tgtagtgttt
    36781 ttttcaagta tatattttgc taccactatg gccctttcct ctatatgaga tctcaaagat
    36841 tacccccctc acataatagc tttaatgata tatatgtaaa aacaccaaaa aatataacaa
    36901 gcttaaccaa atatgattaa acttgttata ctattactta attagactca ttgggtctat
    36961 agatttttct ccactatacg cctctaaatg cacatgtata ccttcttcac tttctatttg
    37021 agaagtacta cctacagtac ctagagattg tccttctgtt accttctgtt ctttcttaac
    37081 actaacattt ttatctagat ttgaatatac tactacaatg ttattgtcac tttttatttt
    37141 gactgattgt ccatattctt catcatcaaa tacatctact actattccgt ttaatagaga
    37201 ttttacttct ttgcctttag tacaactaat atctacacct ttatgagttt cccaaacatc
    37261 aagtgtttta gaataactag gctctttttc tgaatatcct cttattactt tatctccaat
    37321 gtaatttaat tttgttgtac tcgatttatt ttcctctttt gacttagctt tttctaagtt
    37381 ttgttttgaa tccgttgcag tagggatagc atctttcttg tctttttcaa ttaaatgtat
    37441 ttcctcttca ctatctttat tagcattttc cataattcct ttattagaag ccaatttatc
    37501 tacattatta tttgtaaacc aaactccacc tactgctaat aaacaaacac atacaaacaa
    37561 agataaataa aaaccatctt tttctaacag ctttttcttc attttgcacc tccaaatata
    37621 tttctacatt tggattattg acgtgttttt ggcattttat acaattatta gtatatatct
    37681 tttatttttg tatctgtgta gtaatgtgat aatatatcat aatatttata accctcttct
    37741 gccattcctt ctgctcccca ctggctcata ccaacaccat gaccatatcc ttttaccacg
    37801 aaatctatgt atccttctcc aaattttatg tcaaagtttg cagagttcaa cttaaaaaca
    37861 gttctaatgt cttttccagt caattcttta tttcctaatt ttattttttc tacagttccg
    37921 gcatcacttc ttttagttat tgaaacttgt ttacttaaat tattcacatc tatcacaata
    37981 gtgctatatg cccttctaag acttttaaca aaatctgtgt tacttatttt aagtgttgac
    38041 gcaaatttag gggaatactt atcataagga ctttccacag actttaaata aggatatttt
    38101 gcagaaaata cttcttcact attttctgtt tttcctgaag atgtagaaaa ataaagagga
    38161 agtatcgcct tatcattata agttattatt tgacctttag ttcctctaac tgcttcttgg
    38221 attttggaat atttattctt aatccattct tcaccattta attttttaag agtatcataa
    38281 ctcttatatt cttgacaatg tttataatca gtacatacta ctgcattttt atgtttacta
    38341 gatttaccat gttcctgttt atatactaca tatgttctag ctgctacaga ttgagctttt
    38401 aaagcttcta tatcaaactc tgaagacatc tcaccagcta gtactccaca taaatagttc
    38461 tccatgtcca tcttttcggt tttccctgtt atatgattat atacattgat aattggtgct
    38521 tttttattta cagtttcata gttcactgta tttttttctt ctttattacc tttgtcttca
    38581 atatcacttt ttttaatagt tttgtttata gatactgggc tctctggttt ttcagttaat
    38641 tctacatttt tataagaaac taaagttata agtgatggaa ctaacacaga gcaagtcaca
    38701 aatcctaaca aaacaaccaa tgggttcttc atatactctc ctccttagct tttaaaacct
    38761 tgtatttaag tatatgaaca accctattaa tttataactt tcttctataa accaattatt
    38821 aatcttctac tatttcgatt tgaccaccta gtgctgttat cttcttatct atatcaacat
    38881 aacctctttg gatatggtat atttctccta tttgagtttc tccttctgct ataagaccgc
    38941 ataaaataag ggctgcccct gctcttaaat cagtagcgtt tactgctgca ccgtgtagct
    39001 catctacacc attaacaacc gcacttcttc catctatttt tatattagca cccattctat
    39061 taaattcagc aacatgcata aatctgtttt caaaaacagt ttctataact acaccagttc
    39121 cattggctac agtaagcata gccataaatt gtgcttgaac atctgtagga aatcctggat
    39181 gtggtaaagt ttttatatct attggtttta atacttttgg acctacaact cttacagaat
    39241 tgtccatttc tgttatttca caaccagctt ctcttaattt agctacaact ggttttaaat
    39301 gctccattaa aacattttca acagttatat caccttttgt catagctgct gcaaccatat
    39361 aagttgctgc ttctattctg tctggaatta cattatgttc tgctcctttt aactctttaa
    39421 caccttttat ttttatagta ttagtacctg cacctttaac atctgctccc atttcgttca
    39481 agaagtttgc taaatctact atttctggct cttctgctgc attctctatt attgtagtcc
    39541 cttctgctaa agaagctgcc atcattatgt tttcagttgc tccaacagat gggaaatcta
    39601 aatataattt atttcctact aacttttctg ttgctgcttc aacaaaacca tggtccattt
    39661 ctatctttgc acctaaagct ttaaatcctt ttaaatgtaa atctataggt cttgttccta
    39721 tagcacatcc tcctggcata gaaattttcg tactattaaa tctagcaagc aatggtccca
    39781 taaccaaaaa agaagctctc atctttctta caagctcata tggagcttca caagttttta
    39841 tattgcttgc atcaacagta agtgtatttt ctttatattc aacttctgct cctacatgtc
    39901 ttaataaatc tgatataaca tgaacatctc ttaaatttgg tactccattt aatgttgatt
    39961 ttccgtttgc taataaagtc gctgctatta ttggtaaaac tgcatttttt gcaccatcta
    40021 ttttaacact acctttaagt ggattactct tttttactat tatcttagcc atattttttg
    40081 atctcctcat aattaataat ctaattttat aattggtgtg gcaatatata tgagtgtttt
    40141 tccgtcatcc tcattatatt taattcctat atttaaatta attttttccc ctaaatattc
    40201 taattcataa tcatttaata ctttactata tgctgttata gataaaaagt ttacgtcttt
    40261 aacttcatct atttgcttag cactcatatt atataatatt ttttgtaaaa tatcatcata
    40321 tttgttgttt tgtaaccttt ttgtgtattc tccaacaata caagcagaca catctacttg
    40381 agatgaatat ttatttaaca cattttctac gttactataa ataacctctt tatgtttata
    40441 tactttgtta tccaatatgt caactactat gtaactttct ttgttatttt tatttattcc
    40501 ttttatagaa atttctttat cgctaccttt tatagtagca cataattgta ttttatcgcc
    40561 agaccctttt tgattccaat ttattccttt tttatccaac tttagattgt taattatttc
    40621 tataaaaata ttatgaaatt ctttatttga taaattatga tttataacag aattaatttt
    40681 aacattataa aatttaaaat ttgcttctga tatttcaaga gctttactta atctattgta
    40741 tctagtattt atacttgtat ctgcataaga tattgtcatt cctataatca ttaatataaa
    40801 aaagcttata gctaatttta cttttttcat agtaaaaaat cccccttaaa tatgtttttc
    40861 tgtataatag aattattaac aaatttaaga gagatatact ttctcaatat gtatttttat
    40921 acatttttgt atttttcatc taataatctc tttcaaactc ttcaatctca attttctcta
    40981 tccttctcct ggacttgcca atttcttata tgtatcaaat acatcttgca ttaattctta
    41041 tatattctct tctgtaatat aaattactta gtctatactt aaatctataa tctataatct
    41101 ataatctata atctataatc tattcatatt ttaccaacaa aataaacaga taatactttt
    41161 ttatcaattt ccatagctcc aaatgaacat acctaagtac acttcccaat acacaattta
    41221 cacactcttc ctaataaatc aaaaacacct ttgttttaaa caactctatt gcactttcaa
    41281 aaactttatt tgtgttctcc cacttcaatt aaatttgaat tatcaagact ccagcccatc
    41341 catccatcac tataaaggga ggtattttcc actcctatga catttgcata tgttaatact
    41401 tcagcagcac gccatccact tccacacata aatataagct gtttattcac atctatattt
    41461 tccttgtccc acatttctaa aatctcatat ttatttctca ttgtattatc aatattacga
    41521 tattcttcta gtgaaacact atcactacct gaatgtccat ataaagctcc tggtatacgc
    41581 ccttttttat cataatatgt atatccagat acttttccta tatgttcatc ccaagtacgg
    41641 ttatctacta gtataaactt atttttttct tttagttttt gtcttaattc agatgtagta
    41701 acaattaatt gtgagttaac tggtatatct gctccaaaat tagtacatga atgttttgga
    41761 ttactaataa attctaattc atatcctgct gataaccatg agtttgttcc accattcaaa
    41821 actcttacat cttttactcc tatatatctc aatataacag ctagtctata agatgccata
    41881 ggtgtactac ttgaaactat tacagtatca tcctttgtta atccatagtc taaagcaaac
    41941 ttagttaagt tatcatcatt atcaagcatc catgttggag gaggttctat aatatcagta
    42001 tttacatgaa cacttgtagg tatatgccct tttgtatacg attcttctct ccaactcgct
    42061 tcaatcattt ttatattctt tgaatcttca aatgtctcag gaatttttcc atctaatata
    42121 tcttttatta taaaagcagg aactatcatt tgataatttt tatatctttc cattggaaga
    42181 ttttcgtcgt ctgcccattg tttaatatca tatttatata gatatttata tcctttttta
    42241 gataaataat ctgctacaac caaagcatct tttccatttg catcatacaa tactatattt
    42301 ttatctaaat caattctttt agttttcaat gcttgttcta acacttcatc ttttctatct
    42361 gagtatacac ttaaccaatt agcagaaaaa tctactgctc cttttatatg tccacctctt
    42421 tttactccat ctaacttcca gccattataa gcatcattta agcgagtatc aactataacc
    42481 caagcgttat cttgcacttt ttcttgtaaa acttcagtag atattgcctt aagattaaca
    42541 aaataatctt ctttcttttc ttttttaaaa tcatttgtca taatttatac tcccaattta
    42601 aaaaaatttt tatttgaaat tattttacta aaataaagta attttcttat actctattag
    42661 cttcattata ttcttttata aatagttcct tatattctta ttttaaacta ctcactttat
    42721 cttatcacaa ggttactaat accttgtatt ttaatttttc tcataagcta ttattttttt
    42781 atctgatatt gactatatgt ttattaagta ctcactatat tttatatgaa ctatatttat
    42841 cgttccctat acctggtatg gtctatatat ttatcatttt acagatgatt taatatcaat
    42901 ctttttataa aatttattat agcaaaaaca aaacaaattt aatatttatc taaaaaactc
    42961 atcctataaa atacaaataa caggatgagt tcttttcaat aaatattatc tatttaattt
    43021 ttaatctgtt tttattcaac tgttactgat ttagctagat ttcttggctt atctacatcg
    43081 catcctctta gtacagagac atgataagca agtaattgca ttggtacaac tgctaatatt
    43141 ggtgataaaa tatcatctga atttggtata tagattattt tatcagcagc tttctcaaca
    43201 tccttattat ggctttgagc tattgctact acataagctc ctcttgctct tacttcttcc
    43261 atattagaaa ccattttttc aaataacttt tcttgagtag ctatggcaat tacaggagtt
    43321 cctttttcta ttaaagctat tgttccatgc tttagctctc ctgctgcaaa agcttctgca
    43381 tgtatatatg aaatctcttt taatttcaat gaaccttcca ttgctaagct atagtctata
    43441 cctcttccta aatagaatgc atgttcagaa ctaacaactg ttttagcaac ttcttttata
    43501 tattcttcat tgtctagtat ttcttgtatt tttgatggta tttctttcat cttagaaatc
    43561 atactatcat aaaattctct agttattgtt ccttttttga tagcaaagtc taaagctatc
    43621 atgtataaag aagttatttg agtagtatat gccttagttg atgcaactgc tacttcaggt
    43681 cctgcccaag tatagaatac atcatctgat tctcttgcta tagatgaacc tacaacatta
    43741 gttattgaaa gtattcttgc tcctttagcc tttgaatctc ttaatactgc tagagtatct
    43801 gctgtctcac cagattgact aactaatatt actaatgaat tttcatctac aaatgggtcg
    43861 ctatatctaa attctgatgc tatatcagtt attactggta tatttacaaa tttttctatg
    43921 gcatacttac caagtaatcc agcattatat gctgttccac aagccactat ataaacttta
    43981 tttatttttt ctaagtcttc tttagaaata tttatactgt ctagaattat atttccatta
    44041 tcatcaagtc ttctttctaa agtttctctt actcctgttg gttgctcatg aatttctttt
    44101 gacataaagt agtcatatcc acctttagac gcagcttcta catcccaagt tacatgaaat
    44161 acttcttttt caacaagatt tctattagag tcataaactg ttacattttc gtcttttaga
    44221 tgaactactt ctccattttc taagaaataa acatctctag tatattttaa taatgcaggt
    44281 atatctgatg ctataaagtt ttcaccttca ccaacaccaa ctacaagagg actatctttt
    44341 cttactgcaa ctaattcatt tccatgttct ttacatataa cacctaatgc ataagctcct
    44401 cttaattttg atatagtttt gtatacagca tctaataaat taccctcata gtatttatct
    44461 actaaatgtg ctattacctc tgtatctgtt tgagattcaa acttaacacc ttcagaaatt
    44521 aattcttctt ttatttccat atagttttct attatcccat tatgaacaac tgctattgtt
    44581 ttggcttgat taaaatgagg atgtgagttt acatcagatg gttctccatg agttgcccat
    44641 ctcgtatgcc ctatacctaa atttccatca ataggattct tttctaagtc ttctgcaagt
    44701 acagaaagtc tacctttaaa ctttctaata ttaagttctt tttcattaga actattaact
    44761 gctactcctg ctgagtcata acctctgtac tctagcttag aaagcccttc tactataact
    44821 tctgctgcct ttctacttcc taaatatcca actattccac acattatttg tgtcctccta
    44881 aaaatattat ttatatattt taagagttag gtcatataag tttactttgg cttccctttg
    44941 tccataggat tgctcctatt atttaaagaa gtctttcgat ggtaaacaca ccgcagagca
    45001 tccgccgaca attcgattaa ctctgacctc gtcaacttag ttcctatatt actcaataat
    45061 tatgtctata actaagttct ggcgcttaga aaggtgtcct cagtatttat atctgagaat
    45121 accctttaaa ttacgataat ttttcttgta taagattagc taagtttgtt gctaattctt
    45181 ttatttgacc ttcctcttta ccctctaaca taactctaac taatggctca gttcctgatg
    45241 gtcttatcaa aactctacca tttccgtcta aaatagattc tattctttct atctcagttt
    45301 ttatttctgg atattccata tatttgttct tattttcatt ttttattgtt gcatttacta
    45361 atacttgtgg gtattggctc attattgatg caatttctga taaaggtttc ttttcttgca
    45421 agattatatt tgcaagtatt agagaactaa gcactccatc tccagtagtg ttgtaatcta
    45481 aaaatatcat atgtccagat tgctctccac caagattata tccattttta accatatctt
    45541 ctaaaacata tctgtctcca actgctgtag tagataaatt tattccattt tccttagcag
    45601 ctattgtcaa ccctatatta ctcataactg taactaccaa agtatcttgt gccaatttat
    45661 tatttttctt taaatttaag gcactcaata tcattatatg gtctccatca acaatttgac
    45721 ccttttcatt tactgcaatt aatctatcag catctccatc atatgcaaga cctaagtcag
    45781 cattatgttc caaaacagcc ctttgaagtt gttctggatg tgtagagcca catttatagt
    45841 ttatattatt tccatctggt gaactattta ttgaaattac acttgctcct agttcatcaa
    45901 acactattgg tgccacttta tatgacgcac cattagcaca gtccaaaact acttttaatc
    45961 ccttaaagtc agtgcttatt attgatttta ggtagtctac atagtctctt tgtgcacaat
    46021 gttcatgtaa ttttcttcct acattttcac caattggaag acaatcaatt ttgtctatat
    46081 cgtctatata ttcttctatt ttcaattcaa tttcatcatc taatttatat ccattcttat
    46141 taaagaattt gattccatta tattcaacag gattgtgaga tgcagatata accacaccac
    46201 aatcagcacc atattttcta gttaaatatg ccactgcagg tgttggtatt attccaacag
    46261 taataacatc acatccaaca gacataagtc ctgctattaa agatgcttcc aacatatcac
    46321 ctgatattct agtatcctta cctactacta cttttactct gtggtctcct tgagctaaga
    46381 caaatccacc agctctacca agtttatatg ctaaatcaca tgttagttct gtatttgcta
    46441 ctcctctaac tccatctgtt ccaaaatact ttctcactaa agattctcct ttcataattg
    46501 aaaagcttgt aatttgtatt atatttttat agttcataaa atatcattat aggcttaatt
    46561 tcagtcataa aaatatttta atacttatca gcaaaaaaga caatagaaat aattctattg
    46621 tctttttttt gacatctttt tctttattag ttagttgctt tagaacatgt agcatccata
    46681 cctttttgta aagcttctct gtttaatgga acgaattttt cttttctagg tccgaaaact
    46741 tttttgaatg cttctagtac agattctata tctacagtat cagatacttt taagtaagcg
    46801 cctaacatta tcatgttagc aactttatca tttcctaatt cagctgctaa ttcatttgct
    46861 ggtatataat aaacatctac atctgttcta tcaacttttt cttttattaa agaactattt
    46921 actattattt ttccaccagg aataacatca tctttgaatt tttcaaatgc tggtatattt
    46981 aataatatag ctgcagttgc atcatctgtt ataagtggag aaccaactgg ctcattagat
    47041 acagttactg cacagtttgc tgtacctcca cgcatttctg gtccataaga tggtaaccaa
    47101 gaaacttctt ttccttctag cattcctgca taagtaagta attgtcccat agacataaca
    47161 ccttggcctc cgaagcctgc acatattact ctagctgtag acatttactt cacctcctca
    47221 acttcaacat ttttgaaatt tcctaatgga tagtatggta tcatgttgtc tcttaaccat
    47281 tgtaaagcat cgtttggagc tagtccccag tttgtaggac aagtagataa tacttctact
    47341 attccaaatc ctaatcctgc ttgttgaact tggaatgctt tctttatagc ttttttagct
    47401 tgtctaacat gagctggagt atcaactgct actctttcta caaatacagc tcctgttaat
    47461 gtagctaaca tttcacttac tcttattgga taaccttgag tttcagcatt tcttcctgat
    47521 tgagcagtag tagctctttg tccaactaat gtagttggag ccatttgtcc accagtcata
    47581 ccataagttg tattgtttac aaatatagta gttatttttt ctcctctagc agctgcatga
    47641 actatttcag cagtaccaat tgaagctaag tctccatcac cttgataagt gaatactgta
    47701 ttttcaggat gaactctttt tattcctgta gcagcagctg gcgctctacc atgagcagct
    47761 tcttgagtgt cacagttaaa atatttatat cctaaaactg aacatccaac tggaacaaca
    47821 cctacagcat cacctaatac tcctagttct tctaatactt caccaactaa tctatggatt
    47881 ataccatgtg tacatcctgg acagtagtga gtttgagtat cttgtaatcc ttcagttttc
    47941 ttaaatacaa cagccattat ctagcacctc ctgcaaccaa ttctccggca ataatttttt
    48001 tagctttttc aactatttct gctggtgttg gagtcattcc tcctggtctt ccatggaagt
    48061 aaactggtaa tttaccttct actgccattt taacatcttc caccatttgt cccatactca
    48121 tttcaacagt caatatgttt ctagcattag gaatttggtt gaatgcttcg aatgggaatg
    48181 gccataatac tttaggtctt ataagacctg cttttattcc ttcttctctt aatatatcaa
    48241 ttgcgctttt tactactctt gaagtagttc cataagctgc aaatacaaat tcagcatctt
    48301 ctgttttgta catttcgtat tgtacttcat tcttttccat tgcatcaaat ttttcttgta
    48361 aatgccaaca atggtcttct agtacttctg gctctaagta tagagagttt attacattag
    48421 gttttctttt tcctttagtt ccaacagttg cccaatcttt aggaggcaat tctcttttct
    48481 tctcaggagc tctaaattca actggctcca tcatttgacc tatcatacca tctgcaacta
    48541 ccataactgg tgatctgtaa taatctgcaa cgtcaaaagc ttccattatc atatcaacag
    48601 cttcttgaac tgtagctggt gcgaatactg gagttctgta gtctccattt cctccacctc
    48661 ttgtagacat aaagtagtca gcttgtgaag gttgtatact tccaagtcct ggaccacctc
    48721 tcattacatt aagtacaaca caaggaactt ctgctcctac tgcatatgtt ataccttctt
    48781 gctttaaagc aactcctggt gaagatgaag aagtcataac tcttgctcct gcacctgctc
    48841 caccataaac catgtttatc gcagaaactt ctgattcagc ttgaacgaac gctccaccta
    48901 ttttaggtaa ctctcttgat aaatattctg gtaattcact ttgtggagtt attgggtaac
    48961 cgaagaaata tttgcaacca gcttctatag ctgcttttcc aaatgcttcg ttacctttca
    49021 taagtatctt agccattaaa attccccctt aaatattaat taaattaatc tctttctact
    49081 gttataacta catctggaca catagttgca caacttgcac atcctatgca tttttccatt
    49141 tcaaaaacag ttgctgggtt ataccctttt ttgtttatta catttgagtc taattgtatg
    49201 atttttactg gacatgcttc aacacacaat ccacaacctt tacaacgttc ttgattaaaa
    49261 gatacttttc ctttagccat ttacctaagc ctccttaaac tttctatata tttgagctca
    49321 aactacatcc agtcttctct catatataat tttataggaa aaatttctcc ttctaaatct
    49381 tttggtaact gttcaacaag attttctaaa catgcaacat atcttatcgg tatattacat
    49441 ttttcagaaa cttcttttgc aactttctga cctcttaaaa catcatcaat agtagtaaac
    49501 ctaataagat gagtattatt aattagacct gttaccttta atttagaaga tttttctatt
    49561 tcttttatat attggataac ttcttcagaa gtttgagttt tctccctatt tgcatttatt
    49621 acaaaaagca tatcataatc gccttctttt aacaaatgac taaatcttcc tataacccta
    49681 gcacctacat tatctccacc taaatctata acagaattgt atgaatggtc taccatagga
    49741 gacattacct ctgctgatac tgctggtaaa tctaatgttg gagcattaat tgagctatct
    49801 attggttgta tacctaagga tttcattaac tctttctttt ctctagttct aaagtataca
    49861 tttaccacat ctaaatcggc tatagcaact ttgccagaaa ccatatctct taacttaaca
    49921 acatagttca tcgcaaattc acttttacca cttccatagt gaccagttat gattcttatt
    49981 cttttatcat tagttatcat aaacttgagc ctcttcttca ccagttaaaa ctctaagtcc
    50041 accttgagct aatgcaatca tttcatcttc acctggataa acttttacat ctgctataaa
    50101 tttaactcta tctgcaatca tttctgtaaa catttttgaa tatgcgattc caccagttaa
    50161 taatattgct tttacatctc ccttaagaac tgcagcacta gctcctattt ctttagagat
    50221 ttgatatgcc atagcttcat atgctaattt agctttttca tcaccagctt caattctttc
    50281 ttcaacttct ctagcatcat tagtgtttaa gtatgcaact aatccgccat taccttttat
    50341 tttcttttta atttcatctt gagtatattt tccactaaag cacattttta ctaatgcacc
    50401 tactggtagt ccaccacttc tttctggaga gaaaggtcct tctccatcta atgcgtttgc
    50461 aacatctact attttaccat ttttatgagc tccaacagaa actcctccac ccatatgtgc
    50521 aactataaga tttatatctt catatttctt gtttatttct ctagcatatc ttcttgctat
    50581 tgccttttga tttaaagcat gtactacact tgctctactt atttcaggca taccagaaat
    50641 tctagcaaca tcttctaatt catctacaac aacagggtct actatgtatg aaggaacatt
    50701 tacttcttca cctatttgtt ttgctattat tccacctagg tttgaagcgt gttctcctaa
    50761 aactcccact tttaaatctt caatcatagc agcacttact gaataagtac caccttttat
    50821 aggtttaaga agtcctcctc tacctactac agcatctaat tcagatgttt ttactccacc
    50881 ttcttttaga gcttcttcta ttacttgttt acgaaattca aattggtcag acaccttctc
    50941 atattttcct atttcttctg aagaatgtct taaagttttt tcaaatacta aatcctcatt
    51001 atcaaataca gctattttag ttgatgtcga accaggattt attgttaaga ttttaaatat
    51061 tttgctcatt tgcctatttc ccccttaaaa ttatgccttt gctgccatta aaacacctaa
    51121 agctattgag tttagtttag tttcttcact gtctgctcta gaagttaata ttattggtgc
    51181 tttagcccca actataactc ctgcattttt tgattttgag aagaatacca aagctttata
    51241 taatatgtta ccaccttcaa tatctggggc taataatata tcagctcttc ctgctacagg
    51301 atgatttata cctttatgtt tagctgcttc taaagatact gcattatcaa ttgcaaaagg
    51361 tccaccaacc atacaacctt tgatttctcc tctttcatac atttcttcta gttctttagc
    51421 ttcaactgta tctttcattt ttggatttac tttttctttt gcgcatattg cagcaacttt
    51481 tggttcactt atatctaatg aatgtgctac tgtgcaagca ttttctatga tttgcttttt
    51541 agtatttgta tcaggagcta agttcatagc tgcgtcagtt acgaaaaata atctatcata
    51601 tccctctaca tcaaatactg ctacgtgact taatacattt ccagttctaa gacctacttc
    51661 tttatttaaa actgctttta gtattattga tgtgtctact aagcctttca ttaccatgtc
    51721 ggcttttcct tgtgaaacta attcaacaga ttttagagat gcttctgcta aatcttttat
    51781 atctatcagt tcataatttt cgatatccat gtctatgctt tttgcaattt ctttagtctt
    51841 ttctatatct cctactaaaa tggcatttgc tattttttct tttctagcca tttcaactgc
    51901 cattaaaact tctttatctt ggcaacatgc tactgatata gttttaggtc ctctttcttt
    51961 tgcaaactta attacttctt caaaacttct catgcatttc cacctcatct tgaatttttt
    52021 gaaatagaac tttttatatc tcaattaaat tataactcgt tcagcaacgt tttcctagag
    52081 ataattgaaa tatttaattc aaaatattta tttaaatcta tttatcagtc ttttttcata
    52141 tatctagcgc tttttagatt taacaaatat ctcattgtcc ttattttata atataactaa
    52201 aataaacaag atgcaacaaa aacataaaat taacaaactt aattttatag gtttttttgt
    52261 cgcatcttgt aacaactaaa tattcgaaat atttgttcat tccacttcaa caatattagg
    52321 ttctatattt atttttttaa attgatatgt tgtttcatat tttattttat atttactatc
    52381 ttcctcagga ccttgtgata aatcaatata taatgaaata tcttttttat ttaacttact
    52441 caaatcctcc attgactcta caacaacttt tatatctaca tcagaaatta catttggatt
    52501 atccatattt gttgggatat ttcttaattc aatatctccc gcattatata aaaattctgc
    52561 actcaattgt tttgtatcat ttaatttaat tgttatagag ctatcctcaa gagttatacc
    52621 ctctggaatt tctaagctaa cttctttttc ttcaccatta gccaaatcag ctaagtcaat
    52681 aggttttgtc ttaatataac ttattttgtc tatatcttct ttctttcctt ttattgtaac
    52741 ttgttcctta cttaatttat agtttttcag tacatcatta tctttattat catttagact
    52801 tactcttatt gggacaattt tttccttcaa tagttctatc tttgcagtca caaaggatga
    52861 acttaatgtt actccttcaa ccttagttcc atcactattt aatggtatta attgcaattt
    52921 tttagaaaaa tcatctgtct cattaccaac atctagatta gctcttacac ttttgacttc
    52981 tttaactaga gttcttggac ctgatacatc gacaaattcc ttactaagtt caattttatt
    53041 tatatttctt tttgaatttc cacttacttc tacctttata tctctttttt cttttatgtt
    53101 tttttcaaga tttactacta aaacatcatg cttaaattct agagtaacac cttgaggaat
    53161 atttgctttt aaatatactt ccttctgtcc ttgtattggg tcttcaatgg ttccatatac
    53221 atgtatatct tcttttttaa cactttgtac ctttgataaa ctacctttta tatatacatc
    53281 tgctgttaat ttttcgtctg gatatataac aagattttta tcctttaaat cactcatatt
    53341 acttatagat acaggtatat cttcaaaccc tttagtttct tcagggtcaa ctacagccat
    53401 aacatacatc cataatgcaa ttgcacttaa aaatgatatt atttttattt tggtattatt
    53461 ttttagtcta tttatcattt aaatatacca cctttgaaaa aacttcttgt ttctgtattt
    53521 gtttttaaat tactacgtaa tatattcatc attctttctc tagaaatatc tctatataac
    53581 ttacctgctt tagcaattga tacgccacct gtttcctctg atacaatcaa agttatacag
    53641 tcagacacct cacttacccc tattcctgct ctatgtctag tacccaaatc tttacttaaa
    53701 tccttacttt ctgtcaatgg caaaaaacat gcagctgctt ttaccttaga atctctaatt
    53761 acaacagctc catcgtgtaa tggtgtattt ggtataaata tatttattaa tagttgccta
    53821 gaaatttcag catcaataat agttcctgta tttattatat cacttattct agtttctctc
    53881 tccattatga taagagctcc tattttttgt ctagaaagtg aatataaagc ttctacaatt
    53941 tcttctatat ttctattgag agtttcttca gaagtattta cattctttcc aaataaatta
    54001 aactttgctc ttcctatatg ttcaagtcct gctctaaatt ctggttgaaa aattataaga
    54061 gcagctataa ctccataatc taaagcttta agagatatcc aataaacggt atgcaattta
    54121 aaggtgttac taagttgagt tgctaataaa agaaatatta tacctttaaa cacttgttct
    54181 gctcttgtat cttttataaa cataaatatt ttgtaaaaaa tatacgctac tatagatatg
    54241 tcaattaaat catatatact cattcttaat attatattaa aaaatccatt taaaaaagaa
    54301 tttatatcta acacagtttt atcctcctgt ttgataactt cttaattatt tacactaagt
    54361 attatactat ataaatctaa ctctatacaa actatttaac ttttatgtaa ataattctag
    54421 ttttatattt ggagattgtt aaataatctc taaacacatt aaaaatatca acttaataaa
    54481 tacatatttc ttattaaagt tagtttttac tcaaataact caaaccatca aggcgcgaat
    54541 acaaaatagt actcgcgcct taattcagtt ttatgttcta aaatatctta atatatcttt
    54601 gtttaatata tattaattat tataaattct ataatccact tattaactat aaacaaatac
    54661 aaaatctaaa tattacttat catcaatatt attccattag attcattttt atattaaagt
    54721 aataacttat ttcatatcta gattagataa atttatttta atatcttact ataaactatc
    54781 attaaaactt attatgtata actagatata atctcctaca gtgaaaataa tacacaatac
    54841 ctaaagttat atatccattt cacagtataa taatttattt agtataactt ataaatatta
    54901 cattaaattg taaattcact atagtctcta attttttata atttcttata cttattgttt
    54961 agacaaaaat atgctcatga atctctttat aaataatttc ataagttatt tcaatatata
    55021 aataccataa agtatacaat ataatgtata taactcttac taattagtta tatttattat
    55081 atttaactga tgccttcata aacatcttgt agactattat acattaccct ccgtatgttt
    55141 acaatattaa tgaatatact gtaactctat tagaatatac tgtaattttt acatagttta
    55201 aagtttataa ataaaaagac acaggtaata tacatgtttc ctgtgtcttt ttaaacaata
    55261 taaaagttta ctataattta tagtaaactt ttcttaatga gcgcacaggg attcgaaccc
    55321 cggacacacg ccttagaagg gcgttgctct atccagctga gctatgcacc caagttatta
    55381 tggagcggga aacgagattc gaactcgcga cttcaacctt ggcaaggttg cgctctacca
    55441 ctgaactatt cccgcttatt taatttggcg acctggaagg ggctcgaacc ctcgacctcc
    55501 agcgtgacag gctggcattc taaccaactg aactaccagg ccgcgaatgg tgggaccaac
    55561 agggctcgaa cctgtgaccc cctgcttgta aggcaggtgc tctcccagct gagctatggt
    55621 cccatttttg gagcgggtga aggggatcga accctcacag ctggcttgga aggccagaac
    55681 tctaccattg agctacaccc gcatatttaa ttgaattggt gactcgtagg ggaattgaac
    55741 ccctgttacc gccgtgaaag ggcggtgtct taacctcttg accaacgagc cgttttaatg
    55801 gttgcggagg caggacttga acctacgacc ttcgggttat gagcccgacg agctgccaac
    55861 tgctccaccc cgcgatattg ttttataagt gccgaagacc ggaatcgaac cggtacgaga
    55921 ggtaagtccc gcaggatttt aagtcctgtg cgtctgccag ttccgccact tcggcttttt
    55981 tggctccaag ggtggggctc gaacccacag cctaccggtt aacagccggt tgctccaccg
    56041 ttgagctacc ttggaacatt t
//
LOCUS       DAEHWO010000016        55258 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEHWO010000016 DAEHWO010000000
VERSION     DAEHWO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55258
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.016"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            49..1863
                     /locus_tag="KNP54_001246"
     CDS             49..1863
                     /locus_tag="KNP54_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0892153.1"
                     /translation="MTLKYKCYDMPLNTTLNYNQSTGAYEGTINYNQDPEYLNVWELQ
                     GITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLRKTSSPITE
                     LTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPILLVEKNNV
                     PNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRYETSLLIAK
                     EIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTYKWLKSEDL
                     QNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFYTDDELEAV
                     LVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKIGGGLTS
                     KVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYNLNTSLA
                     TTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNKQGHGVEVF
                     YKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRSNDMPAV
                     LVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            2105..4018
                     /locus_tag="KNP54_001247"
     CDS             2105..4018
                     /locus_tag="KNP54_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892154.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERSLRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYREILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            4011..6230
                     /locus_tag="KNP54_001248"
     CDS             4011..6230
                     /locus_tag="KNP54_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBF0892155.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDNLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            6339..7169
                     /locus_tag="KNP54_001249"
     CDS             6339..7169
                     /locus_tag="KNP54_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBF0892156.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            7159..10626
                     /gene="addB"
                     /locus_tag="KNP54_001250"
     CDS             7159..10626
                     /gene="addB"
                     /locus_tag="KNP54_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBF0892157.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            10626..14453
                     /gene="addA"
                     /locus_tag="KNP54_001251"
     CDS             10626..14453
                     /gene="addA"
                     /locus_tag="KNP54_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBF0892158.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGCRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVNNPDSDY
                     YGEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            14499..15710
                     /locus_tag="KNP54_001252"
     CDS             14499..15710
                     /locus_tag="KNP54_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBF0892159.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            15697..19224
                     /locus_tag="KNP54_001253"
     CDS             15697..19224
                     /locus_tag="KNP54_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0892160.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKDNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            19355..20608
                     /locus_tag="KNP54_001254"
     CDS             19355..20608
                     /locus_tag="KNP54_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBF0892161.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            20757..21809
                     /gene="ytvI"
                     /locus_tag="KNP54_001255"
     CDS             20757..21809
                     /gene="ytvI"
                     /locus_tag="KNP54_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBF0892162.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            21899..23125
                     /gene="pepT"
                     /locus_tag="KNP54_001256"
     CDS             21899..23125
                     /gene="pepT"
                     /locus_tag="KNP54_001256"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBF0892163.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            23332..24384
                     /locus_tag="KNP54_001257"
     CDS             23332..24384
                     /locus_tag="KNP54_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBF0892164.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(24719..25288)
                     /gene="yfcE"
                     /locus_tag="KNP54_001258"
     CDS             complement(24719..25288)
                     /gene="yfcE"
                     /locus_tag="KNP54_001258"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBF0892165.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(25313..26113)
                     /locus_tag="KNP54_001259"
     CDS             complement(25313..26113)
                     /locus_tag="KNP54_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBF0892166.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            26248..27108
                     /locus_tag="KNP54_001260"
     CDS             26248..27108
                     /locus_tag="KNP54_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892167.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            27108..27794
                     /locus_tag="KNP54_001261"
     CDS             27108..27794
                     /locus_tag="KNP54_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBF0892168.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            27846..28388
                     /locus_tag="KNP54_001262"
     CDS             27846..28388
                     /locus_tag="KNP54_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892169.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            28467..28934
                     /locus_tag="KNP54_001263"
     CDS             28467..28934
                     /locus_tag="KNP54_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBF0892170.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            29643..30779
                     /locus_tag="KNP54_001264"
     CDS             29643..30779
                     /locus_tag="KNP54_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBF0892171.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            30838..31620
                     /locus_tag="KNP54_001265"
     CDS             30838..31620
                     /locus_tag="KNP54_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBF0892172.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            31639..32649
                     /locus_tag="KNP54_001266"
     CDS             31639..32649
                     /locus_tag="KNP54_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBF0892173.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            32668..33465
                     /locus_tag="KNP54_001267"
     CDS             32668..33465
                     /locus_tag="KNP54_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBF0892174.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            33563..34408
                     /locus_tag="KNP54_001268"
     CDS             33563..34408
                     /locus_tag="KNP54_001268"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBF0892175.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            34495..35670
                     /locus_tag="KNP54_001269"
     CDS             34495..35670
                     /locus_tag="KNP54_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBF0892176.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            35865..36767
                     /locus_tag="KNP54_001270"
     CDS             35865..36767
                     /locus_tag="KNP54_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBF0892177.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            36781..37785
                     /locus_tag="KNP54_001271"
     CDS             36781..37785
                     /locus_tag="KNP54_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBF0892178.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(37929..38156)
                     /gene="acpP"
                     /locus_tag="KNP54_001272"
     CDS             complement(37929..38156)
                     /gene="acpP"
                     /locus_tag="KNP54_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBF0892179.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            38328..38753
                     /locus_tag="KNP54_001273"
     CDS             38328..38753
                     /locus_tag="KNP54_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892180.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            38801..39007
                     /locus_tag="KNP54_001274"
     CDS             38801..39007
                     /locus_tag="KNP54_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892181.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            39189..39368
                     /locus_tag="KNP54_001275"
     CDS             39189..39368
                     /locus_tag="KNP54_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892182.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            39402..39602
                     /locus_tag="KNP54_001276"
     CDS             39402..39602
                     /locus_tag="KNP54_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892183.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            39855..40871
                     /gene="ccpA"
                     /locus_tag="KNP54_001277"
     CDS             39855..40871
                     /gene="ccpA"
                     /locus_tag="KNP54_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBF0892184.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(40994..41392)
                     /locus_tag="KNP54_001278"
     CDS             complement(40994..41392)
                     /locus_tag="KNP54_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892185.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            41604..42515
                     /locus_tag="KNP54_001279"
     CDS             41604..42515
                     /locus_tag="KNP54_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892186.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDYDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDE
                     ELYNINEQESEYNYNEKNTKTRAKKKR"
     gene            42630..42810
                     /gene="ssrS"
                     /locus_tag="KNP54_001280"
     ncRNA           42630..42810
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KNP54_001280"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            42993..44210
                     /gene="cdeC"
                     /locus_tag="KNP54_001281"
     CDS             42993..44210
                     /gene="cdeC"
                     /locus_tag="KNP54_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBF0892187.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(44311..45633)
                     /locus_tag="KNP54_001282"
     CDS             complement(44311..45633)
                     /locus_tag="KNP54_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBF0892188.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(45684..46478)
                     /locus_tag="KNP54_001283"
     CDS             complement(45684..46478)
                     /locus_tag="KNP54_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBF0892189.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            46588..48033
                     /locus_tag="KNP54_001284"
     CDS             46588..48033
                     /locus_tag="KNP54_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBF0892190.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            48062..48271
                     /locus_tag="KNP54_001285"
     CDS             48062..48271
                     /locus_tag="KNP54_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBF0892191.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            48291..49685
                     /locus_tag="KNP54_001286"
     CDS             48291..49685
                     /locus_tag="KNP54_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBF0892192.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVIWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            49925..50677
                     /locus_tag="KNP54_001287"
     CDS             49925..50677
                     /locus_tag="KNP54_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0892193.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            50703..51116
                     /locus_tag="KNP54_001288"
     CDS             50703..51116
                     /locus_tag="KNP54_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0892194.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            51120..51863
                     /locus_tag="KNP54_001289"
     CDS             51120..51863
                     /locus_tag="KNP54_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBF0892195.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            51863..52333
                     /locus_tag="KNP54_001290"
     CDS             51863..52333
                     /locus_tag="KNP54_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0892196.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            52350..53108
                     /locus_tag="KNP54_001291"
     CDS             52350..53108
                     /locus_tag="KNP54_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0892197.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            53092..53934
                     /locus_tag="KNP54_001292"
     CDS             53092..53934
                     /locus_tag="KNP54_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBF0892198.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(54094..54999)
                     /locus_tag="KNP54_001293"
     CDS             complement(54094..54999)
                     /locus_tag="KNP54_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0892199.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
BASE COUNT        22442 a         5761 c         9821 g        17234 t
ORIGIN      
        1 aaatcaaaag ttagtgtcaa atttaaagaa aaaccagatg cagatagcat tacattaaag
       61 tataaatgct atgacatgcc attgaataca actctaaatt acaatcaatc aactggggca
      121 tatgaaggaa ctatcaatta taaccaagac ccagaatatc taaatgtttg ggaactacaa
      181 gggataacaa taaacagcaa aaataatcct aaaactttaa acagacaaga cctagaaaag
      241 ctgggattaa atttaaaaga ctataatgta acacaggaat gtataattga agatataact
      301 tctagaaaag atgtaaataa atatttgaga aaaacttctt cacctattac agaacttaca
      361 ggaagtgata gatatgaaac agcagttaaa ataagtaaag agggctggaa aaatggttca
      421 gataaggtag ttataataaa tggggatgta agtatagatg gcattatatc aactccactg
      481 gcaaccacat ataatgcacc aatacttttg gttgaaaaaa acaatgtacc taatagtgta
      541 aaatcagaat taaagcgcct aaaccctaaa gatataatta taattggaga tgagaatgct
      601 atttctaaaa ctactgctaa tcaaattaaa tcaactgtaa atgctagtca aacacgttta
      661 aatggttcta atagatatga gacatcttta ttgatagcaa aggaaataga taaaaatcat
      721 gatgtggaaa aagtatacat aacaaatgct aatggcggag aagtggatgc acttactata
      781 gcagcaaaag caggtcaaga caagcaacca attatattaa ctgataaaga tagtattaca
      841 gacaatacat ataaatggtt aaagagtgag gatttacaaa atgcttattt tataggtggt
      901 cctcaaatga tatcaacaaa tgttataaat aaggtaaatg gaataactaa agatagtgtt
      961 actaataata gagtatacgg agcagataga cacgaaacaa atgcaaacgt aataaaaaaa
     1021 ttctatacag atgatgagtt agaggctgtt ttagtagcta aatcagatgt acttgttgat
     1081 gctttagcag caggtccatt ggctgcgaac ctaaagtctc caatacttat aacaccaaag
     1141 acgtatgtat ctgcatacca taaagataat ttagaagcta aatcagctaa taaggtatac
     1201 aaaataggag gaggattgac ttctaaggta atgagctcta tagcatcatc attatctaaa
     1261 cacaatacga ctccaacaga accaggaaat agtgggggca agacagttat gattgaccca
     1321 gggcatggtg gttcagcacc tggaaattca tctggaggaa tgattgaaaa agattacaat
     1381 ttaaatactt cacttgcaac aactgaatat ttacgttcaa agggattcaa tgtaataatg
     1441 acaagagaca cagataagac tttatctctt ggaaatagaa ctgctctatc taattcattg
     1501 aaaccagatt tatttacaag tatacattat aatggctcaa ctaataaaca aggtcatggt
     1561 gtagaagtat tttataagct taaagataaa aatggaggga ctactaaaac tgtagctacc
     1621 aatatattaa atagaatttt agagaaattt aaacttacaa atagaggtat aaaaacaaga
     1681 gtacttccta gtgattctac aaaagattat ttatacgttt taagaagtaa tgatatgcca
     1741 gctgtacttg tagaatgtgc atttttggat aatgaaaatg atatgagttt aataaactca
     1801 tctgcaaaag taaaagaaat gggtacacaa ataggtaaag gaatagaaga ttcattaaaa
     1861 taaatggaaa taaaaatatt taaaaactta atgtaaattt atagttgtaa atttatacta
     1921 aagtcaaaaa atgaaatata agtgtatcaa tagtaagact gtatgtacat ttgcacgtgt
     1981 gaatgcaagt atatatacag tctttttttg tagttaaatg caataatttg aatgtgtttt
     2041 gtaaaataca caatatgata taattagata atatacactt aatttaattg aggaaggtga
     2101 ttatatggaa tatttatttg aaaaaagtag tttaaaagaa tatggaaatg aagctttaga
     2161 taaatataga gaattattag ataaaactgg taataattca aggtgtattc ttttgttagt
     2221 accaaacaat aacacaaaga tacgatatga aaggtctcta agattaaatt atagtgaaga
     2281 actgaaaata acaacatata taagttttgt gaagaaagaa ttagttaaat actggccact
     2341 aataatagaa aaatgtgatg aaataagtac aaaggttgta tctccaacat ttatatcaaa
     2401 tagtttaagt gaatatttaa tagtgcaaaa agttaaggaa aaaaggatac aagaaggata
     2461 ttttgaagat attacaggaa ccaataaatc catagcaaat agtataatga ctaacataaa
     2521 taagtctgca tttaatttaa ttgattttga ttttattgga gaaaaaatat attcatcaaa
     2581 gaaaaataaa gatagtatat atagattttc atacactcaa atggatgaaa ttatatcata
     2641 ttatataaat tccttactat caaattcaat tttagataat gcattaagca tatatttata
     2701 caatcaatac ctacttaatg atgattttta tttaaaaaac ttatttacag aagtgagata
     2761 tataattgtg gatagccttg aaagctcaag taatgcagaa gttgatttta taacagaagc
     2821 attggataat acattacaaa gttatatata ttttgattat agtagggatt attctgtatt
     2881 taataatgtg gatatagact atataaatga gaaaataata tcaaaaatta agcctaaaga
     2941 agaaaatatt aaaaagaagg agattagaat agaagattta tacttattac ctgcaaatat
     3001 agaattaaat caatcaagtc aattatataa tgaaatgtta gatttaataa gtgaaaaagt
     3061 tatatctctt atagaagaag atgtatctcc aagagatata gcaattatat ctcctataaa
     3121 caatagtata ttggagcatc aaattagaga ttctttgata gaaaaaaata tagatgtttt
     3181 tagtactaag aaggataaaa aagctgtgga ttatccatat gggaatgcat tggtagtggc
     3241 tacatgtata ttttatggat atttagattt tataaaagat gatgaatact taagcttttt
     3301 agaaactctt ttagaaataa ataggataaa agcatttaag atttttaatg aaacaagaca
     3361 tttaagtatt gataatatag atgaacatag tcagtatcgt gagattttac agtatattga
     3421 agaaaaaaag aagagtgata taaaaataca tgaattttta actcaatttt acatagataa
     3481 aatgttaaat ttaaaagaag gtaaaaagaa tgttgggtta tgtaaaaaga taatagctga
     3541 aagtgagtct tttagtgaaa gtttaagtct acttgggatg aaaaaagaaa agatatttat
     3601 agaagcttta aaaagtacaa taaacgatta ttactctgtt gtcgatatag aagagttgaa
     3661 atccaaagac aaaatagtaa taactactcc ttattcatat atatcatcaa atatagatag
     3721 aagtatacaa atatgggtag atataggaag taatgcttgg aatatgaaaa tagaaaaaga
     3781 tataagtaat ttaattgtac ttagaaaatc ttttgaagaa aaaaagattt atacaaatga
     3841 aatggaagaa tattataaaa aatactatct atacaataca gtatataatt tgttattaaa
     3901 tgcaaagaaa atctatgcat ttaaaagtga atatgcgatt aatggttata tccaagagag
     3961 tatattatat agtatacttt taaaaatctc acataaagga gataaaaatt atgattaata
     4021 taaattatag agaagaccag ataccaataa taaattacga taatggtact atggcagtac
     4081 cagcagtacc aggtgctgga aaaacattta taataacaaa tttagtagct aaactattac
     4141 ttgagcagaa acataagggt ggtaaaatat taattcttac atatatgaat agtgctgtaa
     4201 ataattttaa aggtagaata agaaaaattc ttgaagagaa taaaatagat gatactaatt
     4261 cgtatgaagt aatgactata cacagtttgg ctgtaaaaat aataaaggaa aagccagaag
     4321 ttgtaatgtt aagtgaggat tttaacatag ctgacgattt gcaaaaaagt attatattaa
     4381 atgaatgtat aagtagattt agatttgaag gtggagaaag agcttttaga tggtttttaa
     4441 aggagcaaaa agatgaacgc tggaaagaaa taactcttga agcctgggaa agaggttttt
     4501 ttgaatttgc aggaaatgca ataagtgaac ttaagtataa gggaatttct ccagataacc
     4561 ttgaagaaat attgtcaaga ggacacaaag gaatgcttaa aattatttta ccaatatata
     4621 aattgtatga tagaaaatta aagcaaaatg gattgctaga ttatgatgat atattaattt
     4681 tagcagaaaa aactttaagc ttagacgaag ggcttagaaa gaagtttcaa actagataca
     4741 aatatatatt tgaagatgag tgtcaggact caaatgaaat tcaaggtaat ataataaaaa
     4801 ttatatctag cgaaaataaa aacctagtta gagttggaga tataaatcag agtataacag
     4861 gaacattttc atcatcagac cctaaatttt ttaaagaatt tataaatagt gcagatttct
     4921 gttataggat ggatatgtca aatcgaagtt caaaagatat acttgattta gcaaacactc
     4981 ttgtcaagta tgttacaaag gaatttagac agaaagaatg tagacatgct cttgaagata
     5041 tgcaaataaa aactgtgcca aatggaatgg gatataaaga aaatcctaat ccagaacatt
     5101 ataatataaa tgtaaagtgg tatgagagtt ggaaaattga aatagagcaa actgctagat
     5161 atgttaaagg tataaaaaat aaatatccag ataaaagtat aggtatattg gttccattta
     5221 atgaacaagt gacacaagtt gctaaagaac ttagagagaa taatctaact tttgaagaat
     5281 taggaccaaa ttctttgaat aaaaggaagg ttataaacaa catagcatat attattgatt
     5341 ttatgttaca ttgtgatgat gtagaaaagt taatagttgt acttaataaa gtttttatag
     5401 atactgataa tgaagaagaa ataaagtatt ttttagaaga attaaaaaac tattctactg
     5461 aagaaattat ttataatttt gaatttagta agttagataa tgatttaata gaatttaaag
     5521 aagaaagtga catatattta agttttaaaa gaggaataga tattataaaa cagatattag
     5581 aatatccaat aataaggtta gacctcttag ttttgtttat tgggaaaaaa cttaatttag
     5641 aaaaagaaga taaagctgta ctggattata tatcttttta tataaagtat ctagtatcag
     5701 aaaatataaa tatggattta gaagatgtat ataatttatt gtttgatgta aagaacaggg
     5761 tgtttaatca tataatagat gtggtatatg agataaatgg atatgaacca gagcccggta
     5821 gtataacact atgtaactat cataaatcaa aggggatgga atgggattgt gtgtttttac
     5881 taggtcttgt tgaatataat ttccctgaca atattaatca aaagtttcag agtgataaat
     5941 ggtatctaaa agaaaaatat aaaaacccta tggcaattat taaatcagaa gttgaagcta
     6001 tattaaaagg aagtatttca acagattatg ctcataaaac gaagattgat tctataaatg
     6061 aaaagattag acttttatat gtagggatta ctagagcaaa ggaaatgtta gtactttcag
     6121 gaagtgctta tagagatgaa agtgatatag ggaataagag aaaagagcaa aaaccatgta
     6181 tatatttaag cagacttaat caacatatta ttgaaaaaag gtcaaattaa tatataataa
     6241 gttattaaaa gattgcttga aatatatcta aaaggggata aaacaatatg tacagtaagt
     6301 aactactaaa aaataaagtt aagagagaag tgatatgagt gaacgataaa ttaaaatatt
     6361 tttcttatag tcaaaattca attaacacat ataaatcatg tccattgaaa tttaaatata
     6421 aatatattga tagaataaat tggaaaaatg atgatgttgg tagtagagag tattatgaaa
     6481 ctttaaaaac aggaagagat tttcatttga tttgtgaaag atattttagc aatatacctc
     6541 ttggaatcta ttttaatgag gatgataaaa atagtaaaaa gtttttaaag tggatggaaa
     6601 atataaaaaa agttgttcct attgaaaaag gaaaaacgta tttgccagaa tatgaagtaa
     6661 ggatgacatt aaatggggat ataatacagg caaagtatga tttagttgta attggaaata
     6721 acaatataga aatatgggat tggaaaaccg agtctaaaaa gattgactat aaacacgtag
     6781 aaaatagaat acaaactatt gtttatatgt ttttagcaaa agaagtaata cctaaagttt
     6841 taaaaatgga cataaatgtt aaagatataa atatgagata ttatcaacct gaatttgatg
     6901 acttaccaat taccatttta tatgatgaag aaaaacatga agcaaataga aataaaattc
     6961 aaaattatat aagtatgata aaaaacacta attatgaaga acatacatac gaagacaatc
     7021 tatacaatga tatagaaaag gtatataata aagaagaacg tatgtgctat agaaataaaa
     7081 agcattgcaa gtattgtgaa tttaataagt tatgtaatgg caaagaaata gattatagta
     7141 ttttggaggc ggaaatttat gggacttagg tttgtattag gtagaagtgg aagtggaaaa
     7201 tccacctata tactagatga aattaaaaaa gaagctcaaa aaaatgaaac gacatcaatt
     7261 atacttttag ttccagaaca gtacacattt gaggctgaaa atagagtaag taaactattt
     7321 ttaggaaaag aaaaagataa gtatctaaga gttagggtac ttagctttaa gacactaagt
     7381 aatatagttt tttctcaagt aggaggattg acagatgtaa atataaattc tagtggaaaa
     7441 gcaatgatgg tatatagagc tattgaagat gtaagtgaag aattaaatgt gttttcaaaa
     7501 tcaaaatcgc agtctggttt tgtaagttca attacagata tgatatcaga aatgaaacaa
     7561 tacaatataa gccctgaaat gttagaaaat atatctggag aattggataa tgaaacttta
     7621 agtttaaaat taaaagatat aagtaaaata tataattctt ttgaagggaa attgcatgaa
     7681 aattatgtag atgctcaaga tatgttaact tcattggcaa gtaaaattga attaagcagt
     7741 tatttagatg gagcttgtgt ttatatagat gaatttacag gttttacacc aaatcagtac
     7801 aatgtcataa agagtatatt aaataagtct aaaagtgtta atatctcttt gactgtagat
     7861 gatatcaact atattgggta cagtaaatct gatatgtttt ctagaacgaa atttacttat
     7921 tcaaaattga ctcaattgtg caacgaagaa ggcataaaaa tattgccaca agtaaattta
     7981 aacacaggtg ttataaaaag atttgaaaaa gttaaggaat tacagcactt agaaagattt
     8041 tataatgctt atccatataa aatatattca aatccaactg aaaatataaa gataaaagag
     8101 tttaacaatt tatattcaga ggtggaagag atagccagag aaattgtaca tttagttaga
     8161 gataagaatg tcagatatag agatataacc attgctacaa gagatttaaa tagatatgat
     8221 tttttagtac actctatatt taatgaatat aatataccaa actttataga taagaagaga
     8281 gaggcaaaaa gtaatccaat agttatttta attatttcag ctttagaaat gaagaataga
     8341 cgatatgggt atgaaactat gtttaggtat ttaaaaagtg gacttatagg aattgataat
     8401 gatgatataa atttactaga aaattatgtg ttggctaatg ggattaaagg taaaaaatgg
     8461 tttgatgaaa aatgggatta tagaataacc caaagtcttt caggtcaaga aagtgaattt
     8521 gaactggaat taaaagagaa aataaatgaa ataaaaaata gagtattaga gcctatagta
     8581 attttacaag aaaaattaag aggaaaaaat agagtaaaag aaatctgtag atatatatat
     8641 gaatttttat tagatataaa tatgccagaa actatagaaa gtttaatagt aaattttaag
     8701 gataaagggg aacttgatgt tgcaaatcaa tactcacaag tttgggacat agtagtggac
     8761 atattagacc aaatggtgga acttatgggt gatgaaataa tttctttaga aaaatttata
     8821 aaattaataa ccttaggttt tgatgaatat gaattaggac tggttcctcc tagtatagac
     8881 caggtacttg taagtagtgt ggatagaatg aaaaatccag acacgaaata tttataccta
     8941 gttggaacta ctgatggtgt gtttccgctg attacaaagg atagtggaat attgagtgat
     9001 aatgataggg aaagtcttgg aaacaaagga atcgaagttg atattgatag taagactagg
     9061 agttttgaag aacagtttct tgtatataaa gctcttactt cgacatctaa gaatttaacc
     9121 ataacatatc caatatcaga ccatgaaggt aaaacgctta gaccatcaat aattatatca
     9181 agacttaaga agatatttcc aaatatagaa aataaaagtt atttagtgga agaaaataaa
     9241 agcactgata aagatatact taaaaaaata acggttaaat cccctacatt taatgaactt
     9301 ataaacgtaa taaaaaatta tgacagtgat ggttacaata cagaagagat taatagtatt
     9361 tggttagata tatataggta ctatttaaaa gatgaaatct atagttctat aacaaaaaaa
     9421 gttataaaag gtcttagtta tactaatcaa gttcataaga ttgaagagaa aaaaataagg
     9481 tcattgtata aaagtaattc tcttagcata tctaggcttg aaaaatatgc tgaatgtcca
     9541 tttgcttact ttatacaata tggtctaaaa gcaaaaaagc gtaaagagta ttcatttaca
     9601 ccaccagatt taggaacttt tattcataat attttagata ggttttcaaa agaactttta
     9661 caagataatt taacttggag agatattgat gaaaaatata tagaattaaa gataggtata
     9721 atagttgatg aaataatttt aaagatacca ggatatatat taaatagttc tgagaggtat
     9781 aaataccttg catatagatt aaagaatatg ttgacaactg ctataactat aattagtcag
     9841 caaataaaac aaggttcatt tgaaccaata gattatgaag ttaaatttgg caacaatgga
     9901 aaatatccac ctataaaaat ggtgttagaa aatggacaag aagtaagttt aattggacaa
     9961 atagatagag ttgatgaatt tgaagaagga gaaaataaat atataagaat aatagattat
    10021 aagtcaggca ataagtccat aagtctaaca gaaatatatt atggtctaca attacaatta
    10081 cttgtgtatt tagatgcaat ccttgaaagt gcaaaggatg aagatataaa tataaatcca
    10141 gctgcaatac tatattgtag aataaataat ccaatagcaa aatttaatga agataaagat
    10201 gatgaagaaa tacaagaagc aatattaaaa gaacttagaa tgaaggggct tgtagtaaaa
    10261 gactctcaca tagttaaaga gatggataaa tcattaatag atggagaaag gaaaaactct
    10321 ttagtaatac cagtaggtct tactaaggat ggaaatgtag gtaaaagtac ttcagcaata
    10381 agctatgagg atttcaaact gcttagaaaa tatgtaaggc atgctataaa ggatttatgt
    10441 gaagaaatgt taagtggaga aatacgtata gctccatata aacataaaga tggaacatca
    10501 tgtgactttt gtgattactc tgctatatgt cagtttgatt caactataaa agataacaag
    10561 tataaaaatt taaataataa gagtaatgaa gagataataa aaatgatgaa aggagatgtt
    10621 aattagtgag ttctcctaaa tggacaaaag agcaattaga agttatagaa agtagagaat
    10681 gcaatttatt ggttgctgct gctgctggtt caggaaaaac agccgttcta gttgagcgta
    10741 taattcaaat gataacaagt agagaaaatc caattgatat agataagtta ttagttgtta
    10801 catttactaa tgctgctgcg tcagaaatga gagagaggat aggggatgct ataggaaaag
    10861 ccttagatga aaacccagaa aataaacatt tacaaaacca acttgtttta ttaaataaat
    10921 ctagtattac aacaatacac tcattctgtt tggatgttat aaaatcaaac tttcatagaa
    10981 taaacttaga ccctaatttc agaataggag accaaactga atgtgctatt ttgaaacaag
    11041 aagcaataga ggaagtattt gaagatttat atgaagaaag agatgagggg tttttaaatt
    11101 tagttgaaag ttatgcagaa agaggaggag ataaagaagt acaagatatt atcttgggaa
    11161 tatattcatt tgcaatggct tctcctgaac ctaaaaaatg gttgattgac tcagcagaac
    11221 gatttaatat tgatgaaaat tttgattttt cacagtctat ttgggctaga gctatattag
    11281 acactgtaaa aatagagatt aatggtcttt gtctaaatat ggaaagggca ttaaaagaag
    11341 tggaatcaat agaagaatta gaaacttttg cagaaaagtt atccgttgaa tataaaaaaa
    11401 ttgctgacat ttcacaagca tgtaataaat cttgggatga ggcatataaa aagatggcaa
    11461 gtatgtcctt tgaaaattat gtaaaaggag taaaaagaat ttcaaaagat gctccttcgt
    11521 atataaaaga atcaaaagaa aaggcaaaaa ctataagaga taagactaag aagtctttag
    11581 aaagtatagt aagtgctaca ttcaataaag ataatgattc tattagagaa gaaataaaat
    11641 atctttataa catagttaaa ccaatatcta gtgttgtact gagatttgaa gaggaatata
    11701 gcaataagaa aagagaaaaa ggaataatag attttaacga tatagagcat tttgcattaa
    11761 atatacttac agatgtagat gaaaaaggta atattgtacc ttctgatata gcagttggat
    11821 gtagaaacaa gttttatgaa atatttatag atgaatatca ggatagtaat ctagtgcagg
    11881 aagtactgct taaagctgtt gcaaatacag aaactccaaa tagatttatg gttggtgatg
    11941 taaaacagag tatatataga tttagacaag caaagccaga attatttttg caaaaatata
    12001 ataactataa tgataaaaag ggaagctccc atagaaaaat aatgctttac aaaaacttta
    12061 gaagtagaga agaagttgta gatgctgtaa attatatatt tgaaaatata atgaatgaga
    12121 atataggaga aattgaatat acagaaaaag aaagactaaa tttaggtgca aattttaatg
    12181 tggatacaga cgagaaatct attattggtg gagcaacgga gatacaccta atacaaaaag
    12241 ataataaact tgatgatgat attataaatg ataaagacga tagaattaat aacaaagaaa
    12301 atgaaataga ggaagaagaa aaattagata atatacaact tgaggctaga atggttggaa
    12361 acattatcaa agatttaatg aaagtcaatg aagatggaaa aattcaaaag gtctatgata
    12421 agggaataga tggatataga cctgtggaat ttagagatat agttattctt ttaagagcta
    12481 catctgcatg ggctccagtg tttgcagatg aattgatgaa tatggatata ccaacgtatg
    12541 ctgatgttgg agtggggtat tttgatacga ttgaaataaa aacaatattg tcattacttc
    12601 aaataataga taatccaatg caagatatac ctcttatatc tgtattaaaa tcacctatat
    12661 ttggatttac accagaggat ttgattgata ttagagttca gagtaaagat aaaatttttt
    12721 atgaggtttt aaaaagtaca gcagagtatg atggatttac agattctcaa aatgaaaatg
    12781 agtctgagtt tataccaagt gaagagtgca taaacaaaag taaagatttt ttaattaagc
    12841 taaaggaatt taaagaaaag tcaatgtaca tgagtacaga tgaatttata tggtacttgt
    12901 acacaaggac tggatactat gcctatgttg gagcattgcc aggtggaagt caaagacaag
    12961 ctaatttaaa agtattgttt gagagagcaa aacaatttga agaaaccagt cttaaaggaa
    13021 tattcaactt tgtaaatttt atagagaaat taaaaaaatc tagttctgat atgggaagtg
    13081 caaaaacact tggtgagaat gcaaatgttg ttagaataat gagtattcat aaaagtaaag
    13141 gtctagaatt tccagtagtc atatgctctg caatgggtaa aaatttcaat actcaagatt
    13201 ttaaaaagag tattttatat catcataatt tagggtatgg acctcaattt gtagactatg
    13261 agagaaggat ttcttttcca agtatagcca aagaagcatt aaaaagcaaa ataaatatag
    13321 aaaatttatc agaagagatg agagttttat atgttgcatt tacaagagct aaagaaaaat
    13381 tgattataac tggttctact agaaatatac aagatagtat aaagagatgg tcaaatggaa
    13441 ttgaaagttt agatacaata tcacaatacg agatattaaa aggtaaaaat tttttagatt
    13501 ggataatgcc ttgtgtatta agacataggg atttatctaa tctactagaa gaagtaggat
    13561 tagacgcagt ttttaatgtt gaacataatt caaaatggta tggaaagttg tggaataaga
    13621 atgatatttt agtggaaaag aagagtgatg aagaaaaaga aagtattgaa gaaattcttg
    13681 aaaaaataga tgtaaataat cctgacagtg attattacgg tgaaatagaa gaaaaattaa
    13741 actatatata tccatatgaa tttagtacaa gaaaacctgc tactatatct gttacagaaa
    13801 taaaaaagat acaaaataat tatgaagaag agttaataaa tactatattt gaacaaaaag
    13861 taatattaaa aaagcctcta tttattcaaa atgaagaaga aagagaaaaa ataagtggaa
    13921 cagaaagagg tacaatagtc catttagtta tggaggtttt agacttaaaa aatgtaagta
    13981 gtgtaaatga tataaaatca caaataagag gttttgtttc aaaaggtata ataacagaaa
    14041 aacaagctag tatagtaaat ccatataaaa tatataaatt ttttgcctct aacataggaa
    14101 aaagaatgtt gaatgctgaa attataaata gagaaaaatc aatttatgca caagtaaata
    14161 tgaaagacat atatatttat gaaaagctta taaacaatga cgataaaaaa ctttatgata
    14221 atgaaagtgt catgttaaga ggtatagttg atgcttattt tgaagaagat aatcaaatag
    14281 ttttggtgga ttataaaaca gattttgtaa atgaggaaaa tataaatcaa ataatagaga
    14341 aatataaaaa acagttggat ttatatgcag atattattga aactttaact ggtaagtcag
    14401 taaaagagaa atgtatatat ttatttggag ttgatgaagc tgtttgttat tagtttttat
    14461 atataaatta aacctaaaag atagaggaag gggaaaaaat gagatttatt catacatcag
    14521 attggcatct agggaagtcc ctagaaggcc attctagaat tgaggaacaa gcaaagtttt
    14581 gtgaggaatt tataaaaata gtagaatcaa atgaaataga tatggttata attgctggag
    14641 atgtatatga tacttctaat cccccagcac aagcagaaaa actattttat cagactgtat
    14701 caagacttgc caataatggt cagaggtgtg tattaataat ttcaggaaat catgataatc
    14761 cagagagact ctctgcaata acacctctag cacatgaaca ggggatactt atatatggtt
    14821 atccattaag tgctacgata gaagctaagt ataaagggtt tgaaataaca tatgcaactc
    14881 agggatgtac aaaactgaat ataaatggag aaaatattgt ggttgctaca ttaccttatc
    14941 caagtgaaaa aagattaaat gaagtttttt caagtgaaga tgagtttgag aaacaaaaaa
    15001 attattctga aaaggtagga gatatattta gaagtttaga agaaaatttt agaagtgata
    15061 ctataaatat agccgtatca catatatttg taataggtgg agagagtact gaatcagaaa
    15121 gacctataca gttaggtgga agttttttag ttgaaagaaa agatttgcca gaaaaggctc
    15181 aatatactgc actaggtcat ttacataaac aacaaaaagc ttccgaacgt ttaaatgcat
    15241 actattctgg ttctccactt caatatagca aggatgagag agcgtatacc aaaggggcat
    15301 acatagtgga tataaaagct ggtgaaaaac caataattga agatgtatat tttaataatt
    15361 acaaacctat agaagtattt aaatgtaatg gaatagaaga agcactagat atatgtgagc
    15421 aaaatcaaga tagagagatt tggtcatatt ttgaaataaa tactgatgag ataatatcac
    15481 agaatgaaat taaaaaaatg aaggaactat taaaagacat aatagaaata aaaccaataa
    15541 taacatcttg ttatgaacaa gaaagtgtag atataaaaga aaagtctatg gcagagttgt
    15601 ttagagagtt ctattctttt agtaaaggtg tagagccaaa aggagaactt atggatttat
    15661 ttctagatat aataagtgaa gaaggtgaat cagcagatga gaccaattag attagaactt
    15721 acagggctta atagctatat tgataaacaa gttatagact ttgaaaaatt aattgaaaga
    15781 ggtttgtttg ggatatttgg aactactgga agtggaaaat ctacaatctt agatgcaata
    15841 actattgcta tgtatggaaa tatatccaga aatacaaaag aatatataaa cagtgtgtgc
    15901 gataaggcaa ttatatcata cgagtttgag ataggaagca aaaacactag aagaagatac
    15961 attgtagata gaaccattgc tagaagcaaa acaggaacaa agacctctaa tgctagatta
    16021 atagaagtat tgaatgacaa tacccaaaat gttttagctg ataaagttgt ggaagtaaat
    16081 gaaaaagtag cacaggttgt aggattaaca gcaaatgatt ttactaggtc agtagtttta
    16141 ccacaagaca aatttaatga gtttctaaga ttatcacgtg cagatagaag agacatgtta
    16201 gagagaattt ttaatcttga gaaatatgga agaagtcttg gagaaaaagt gaaaaagaga
    16261 aaaaatatac agttacaaaa tttaaaagat ttgaaatcaa aattaagtca atatgatgga
    16321 attacagagg aagtatacaa caatataaac caagaattaa tagagttaaa aaatttggaa
    16381 aaagataagg ataatgcttt agacctagct caaaaatctt atgaagaaag taaaacagta
    16441 tatgaagaac aattaaagtt agaaaaaaat gaacttagaa aaaatgagct tgatttaaaa
    16501 aatagtgaga taaaagaaaa gattgctctt gtagaaaatg atagtaacgc taaaaaggta
    16561 gacccataca taagttcagt tcaaaatcta gaaaaaaaga tagatgaaga tagcttcgca
    16621 gtaagtaatt tagaaaagaa attagcaata ttaaatcagg agcttgaagt tacaaaaaat
    16681 agatatgaaa aaataaacaa aattaagaat gaagaagtcc ctaaattgag tgaagaaaaa
    16741 ataagattgc aacaagcaat aaaattagaa gaagagttag ttttattaga tagagagtta
    16801 aaagagctaa aagaaagtgg aattaattta aataagacta aagttgaatt agaaaaagta
    16861 aagcaggtgt cagagtccag aaaagatgca gttactaaat ctataaaaga agttgaagga
    16921 aagattgata aagtaaatat aagtgcagaa ttaaaacaaa aaatatttct agcatatgaa
    16981 tacgagaaag attacaacaa cgtattggaa gaaaaaaatc aaaagctaaa taaactagaa
    17041 gaaatactca aagagacaga aaatataaat ttaaaagtta gatatattga taaagataag
    17101 aatgatgtaa atcgtaattt agaaaattta tcacttcact tggatgttct tcttaaaaaa
    17161 tgtcctggta agagtgctga tttactttta aaatctgaat atgttactga attaagaaat
    17221 aaagcaaata atactaaaga aaatgaaatt aagaaaagca gtatacaaga tgaattaaag
    17281 ataatacttg aaagtaagtt taatactgaa agggaagtaa atttactaaa tgaaaaactt
    17341 gaaaataata gaaagaacag agatgactta gaaaaagaat tagaagaact aaagtattta
    17401 aatttagcct ctgaacttag acgtgaatta aaagaaaata tgccttgtcc agtttgtggg
    17461 tcaaaacatc atgaaaatca tgatataact aagtatgatg aaaatatatc ttttgtcaaa
    17521 gaaaaactgg agaaattaga aaaagaaaaa ataagtataa gaaacaatat agaggaatta
    17581 aatgctaaag taagtgggta tttatctata gaaaaaatga agactaaaga acttgaagat
    17641 gtaaaaggaa aactaggggg gattccatct agtcaattat taaaaaaact tgatgaagaa
    17701 caaagaaaac ttgcattgtt aaaatctaat attcaggagt gggagaaaga aaaagagagt
    17761 actgaaaata aagtaacatt agctaaagaa gaaaaaaata aaattgaaaa agaagaatta
    17821 aaaataagag agagtctgaa taattataag aaattaacaa gagatttaaa catagaaata
    17881 gaaggtttag aaaataaatg taaaaaactt aaacaggaat acctaggatt aaagacgatt
    17941 actaaagtct ctaatctatt gtcaaaagta aaagaaataa gagagaatga aaaagaatta
    18001 gaattactaa gtactgggca ttcaaattta ttaaaaaata gagactcact agatattaaa
    18061 ataagagaaa atgagagtaa actacatgaa atagagatag aattaataaa ggctagagaa
    18121 ttatatgtag aaaagaaatt gagtagagat aataagtata aagaagttat tagcataacg
    18181 aaaggtgatt tagctaaaaa tcttttacat aatgttgaag aaaatatatg taagatatta
    18241 gaacaagaag aatcaagtaa gaaaaaattg gaagagcaaa gattagaata tgaaaaaaac
    18301 attgctgaaa agcacaatat agatggtaga cttaaaactg ctaaggaaca atataaagac
    18361 caaaaatcaa cactaaataa actattagca gaaaataaat ttgaaagtat atatgcagta
    18421 aaaagagctt tattagatac tgatgcagta aaaaaattga ttgaagaaat actagagcat
    18481 gaagaagaac aaaagttatt atcatttaaa ataaaatcat caaaagaaaa attaaatgga
    18541 agaagcataa agaaggagta ctttgaacag ttaaaagatg aaatttataa tttgaaagta
    18601 gaaataggaa atatatccaa agatattgga gctaatcaaa atcagttaat aacattaaaa
    18661 gactctttag ataagataaa tgattttaat aaacaactta aggtagttga acacaatgtg
    18721 gacttattgg aagaattaga taaatgtgta caaggaaata aatttgtaga atatgtttct
    18781 acaaaccaat taaaatatat agcgttggaa gcatcaaaac gattggatgg aataacaaaa
    18841 ggaagatatg cacttgaaat tgactcaaca ctaaactttg taatgagaga taactttaat
    18901 ggaggagaaa gaagaagcat tgatactcta tctggtggag agacattctt gacatctcta
    18961 tcattagcac ttgctctttc atctcaaata caattaaagg gaagtgcacc attagaattt
    19021 ttctttttag atgaaggttt tggttcatta gatagtgaac ttttagaaat tgttatagaa
    19081 tcattggaaa gattgcatag taataatcta agtgtgggta taataagtca tgtcgaggaa
    19141 cttaaaaata gagttcctgt taagctatta gtttcatcta gtgaggctgg aataggttca
    19201 aaagtaaaaa ttgaatatag ttagaaaata tatgttaatt gaatatatta tctaatattt
    19261 ccaaataata tgtaattgtg atataataaa aactaatatt aaagttattt ataattaata
    19321 ttaatataaa aacatgtaag taggagtgtg gtaagtgttg gaatcgccca ataatttgat
    19381 tcagattatt tttttaatag tattacttat agggtctgca tttttctcag catctgaaac
    19441 ggctttaatg tcgttgagta aaatcagaat cagatatatg caagatgaag gagttaaagg
    19501 agctaagtta gtaagttcat taatagaaaa tccaaataag cttttaagtt ctatattggt
    19561 tggaaataac gtcgtaaata tagcagcaac atccatatca acatctttgt ttataggatt
    19621 aatgggagaa aaaggagtgg cacttgctac agctgttatg acagtattag tattaatatt
    19681 tggtgagatt actccaaaaa caatagcagc aaataattca gaaaaggttt ctctattagt
    19741 atctaaacct ataaaagcaa ttatatttat attaagacca atagtatgga tatttaatat
    19801 aattacaaat attatattta aattatttgg tataacaaat aaaggagcta aatcattcat
    19861 aactgaagaa gagctaaaaa ctatggtaaa tgtaagtcat gaagaaggcg tccttgaaat
    19921 ggaagagaga gaaatcataa ataatgtttt tgaatttgga gatatgcaag ctaaaaatgc
    19981 aatggtacaa agaatagata tggtagctat agatatggaa gatagttatg atgagataat
    20041 acaggtattt aaaactgaaa aattaagcag aatgcctgtg tatgaagaaa ctatagatga
    20101 tattgtagga atacttaata taaaagatat tatattttta tctgatgaag aaatagagtc
    20161 atttgatatt aaaaattata tgagagaacc ttttttcacg tatgagttca aaaagataac
    20221 acaacttctt gaagagatga aacttgaaaa aagtcagatg gctatagttg tagatgagta
    20281 tggtggaaca tctggacttt taactataga agatttagta gaagtcattg ttggagatat
    20341 agaggatgaa tatgatgaag aagaggatga aatacaagtt ataaaagaag atgagtatat
    20401 tgtagatgga agtactaaaa ttggtgatgt taatgaactt attggtgtaa acttggaatc
    20461 tgaggagttt gattccatag gaggttttat aattggacac ctaagcagat tgccagaaga
    20521 aaatgaagta attgaggttg ataatataag attttgtata gaaagtatag aaaaaaatag
    20581 aattaaaaaa ataagaatat atacataatg taataatgtt cttaaattta ttagaagtgt
    20641 ataaatataa aagatatctt ttatatttat acacttcttt ttattttgta ttcaaataaa
    20701 actagtatga aatggacaaa ataaaaatat aaattagaag aaaggagatt tttaagatga
    20761 gcatactaga aaataatttt ttatacaaat taaaaaacaa cactatcttt ttttgtatat
    20821 atacattgtt atttattttt atttacaaag cgtttccata catagctcca ttttttctag
    20881 gtgctataat agcacttatg attaatccta tatcacaaaa gttagaaaat aagtttcgta
    20941 taaataaagg tatctctact cttgttctaa gttttcttgc agtggctata gtcagtacag
    21001 ttactacaat aatagtaata aattcaatga aagaattaat gggattttta aataatatat
    21061 ctgctaatcc tgaggatata agtaatacta ttatgtattt tttaaataaa ataaatgact
    21121 ttatgaaatc atttcaagaa atagccaatt ttgatgtaga acaattagta aacaaattca
    21181 gtggtgaagt aatgcaaatt acaaaaaatc ttcttactag tatacttgga ttggctactt
    21241 ctattccata tattataata tttataatta ccttgtttat tgctacgtac tttatagcaa
    21301 aagaccttga taagattgaa aatagttttt ataatatgtt tactgttgat gttagaaaga
    21361 aggtaaaaaa cgtaaagaaa gaggcagggc tttcacttgt tggatatata agggcctata
    21421 caatacttat ggctataaca ttttttgcaa tctggggaag ttttgcttta tttggattga
    21481 aatacggtct aatagtaggg tttgtaggag ctttaatgga tttaattcca ttcctaggta
    21541 taataacaat atatcttcca gtaattgttt attatttcct tataaaaaat tattttatag
    21601 ctataagtat gactgtgata ttttttgttt tgtctttgat tagagaaata cttgaaccta
    21661 aactagtatc agtaaatgtt ggactaaatc cattagctac cctagcagcg atttttattg
    21721 gaatccaagt aaaaggaata attggagtaa ttttttgttt gggtttggta tgtatgcatg
    21781 atatacttaa gaaggtggat attttttaat tataataatt gatagatttt ttaaaaataa
    21841 aattttattc acaggtaaat aaaaaaatat taatcttatt aagaaagagg gtatatacgt
    21901 gaaacaaaaa gtagtggaaa gatttttaaa atatgtatca tttgatacaa catctaattc
    21961 tcagtgtgag aactgtccat cttcagaagg tcaaagagtt ttagctaagt atatagttga
    22021 agagctaaaa acaatgggtg ttgatgatgt gagtttagat gaaaatagtt atataatggc
    22081 tactttaaaa ggaaatactg atggtgtgga tactatagga ttcatatcac atttagatac
    22141 aattgaagat gttagtggaa aagatattaa accaagaata atagaaaatt atgatggaaa
    22201 agacatagtt ttaaatgaag cgttaaatgt tattacgtat gtaaaggatt ctccagagtt
    22261 ggaagaattt aaaggtgacg atttaatagt cactgatgga acaactctac ttgggtctga
    22321 tgataaagct ggtatagctg agatagtgac tgcaatagag tatctaataa atcatccaga
    22381 aattaagcat ggagatataa aaataggatt tacaccagat gaagaaattg gtagaggtgc
    22441 tgatttattt gatgttgaaa aatttggagc aaaatatgca tatactttag atggaggaat
    22501 agttggagaa cttgaatgtg aaaattttaa tgctgcaaat gcaaccatta ctatacatgg
    22561 tagaaatgtt catccaggtt cagctaaaaa taaaatggta aatgctatac atatagctgc
    22621 tgaaatatca gaaatgttcc cagcagatga aagaccagaa acaacagaag gatatgaagg
    22681 attttggcat ttaaattcta taggtggaaa tgtcgagaat gtaagtatgg cttatattat
    22741 tagagaccat tgtaaagaaa aatttgaaaa tagaaaatct attatgatag agaatataga
    22801 aaaaataaat aagaaatacg ataatagagt ggaattggat ttaaaagact cttattacaa
    22861 tatgaaagaa aagattgagc cagttatgtt tatagttgat atagctaaag aagctatgga
    22921 ggaattaggt ataaaaccac gtttagttcc tgtaagaggt ggtactgatg gagcaagatt
    22981 atcttttaat ggattacctt gtccaaatat atttactggt ggattaaact tccatgggaa
    23041 aaatgagtgt ataccagtta gttctatgga gaaagctact aaactaattg taagaatagc
    23101 tgaaaaatat gctgaaagag tttagttaaa aagtatttaa aaattaagca tttaaagtta
    23161 taatagctat atcattcttt ataagtcaag ctgattataa gcttgtgttg tacttaaaat
    23221 ggtatagcta tttttgtaat tatttttata aaagataatt atttttagtt tagggtatca
    23281 ataaaaagta tgaatatcaa taggtattaa catttaaaag ggggaattgt attgaaaatt
    23341 aaatctaaaa aaataatagc atttgcactt tcacttggga ttatgttgcc aagttgtgta
    23401 tatgcagaca ctattagtaa aaatcaaaat gcacaggtag atatgaacaa ttatcttcaa
    23461 ggtagaaaat ctccaaagga ggaaaaactt attggtgaag atagatttga tacagcgata
    23521 aaaatatctc aaagtggttg gaataatggt tcagaaaggg tgtttctagt taactcaaat
    23581 tcattgccag atgcattggc ttcaactcct ttggcaagta aattggatgc accaatactg
    23641 cttacaaata aaaatagtat accatataat gtaacagagg aaataaaaag gcttaatcca
    23701 gcagaagtta ttttaattgg aagtgaagga gctatttcat caagtgtaaa agaatctctt
    23761 gaagatatgg aagtattagt cagtagaatc ggtggagcag atagagaaga aacatcttta
    23821 cttcttacta gacagctaga tgatactggt gatttaggtg tctcaaaagt ggcagtggtt
    23881 aatgggtata atggactggc agatgcaact tcaatatcaa gcccagctgc aagtgataat
    23941 acagctataa tatatacagg taaggatagc ataagaagtg aggcaaagaa ttttattaca
    24001 caaaactcaa ctaagacata catagtaggt ggggagtaca gtataagtaa aaaacttgaa
    24061 ggacagttag taaactcaga aagactagca gggacagata gaaaagatac taatgcgaaa
    24121 gttttagaaa agttttatgg aaaatcaagt aaggttaata atatgtattt tgcaaaagat
    24181 ggaagtggta gagaagctga tttagttgat gggcttgctg ctggagtatt agcatcaaaa
    24241 acaaagtcac ctgtagtact tgcaagtgga agtttaagta gtgcacagaa aagttttata
    24301 aaaaaagtaa aggctgataa atttgtacaa gttggtggag gtaaaaatag taaaccatat
    24361 gcagaagcat tagccttaca gtaatattgt gtaaatcaaa attaatatat aataatagca
    24421 agtaaaccaa gttgcacttc aatatatata ataaaataag taaactaagc tatgtttcaa
    24481 tataatatat aataaaataa gtaaactaag ttatatttca gtataatata taatgaaata
    24541 agtaaactaa gttatatttc aatatagcat ataataaaac aagtaaacca gattctattt
    24601 aattagaagt ttaaggtatt gtacttaaac ttctaattga gatagaaata aaatggttta
    24661 cttgttttta ttatgagttt aataaattaa agcttatttt atttttatta aaaatttact
    24721 aatcattgat atttattata tttccagtat tgatgtcaat taagtttata tcaagttcaa
    24781 gctcatcctc atcatcagtt tttatgatat ctataattgc gacagaatgg cttccatctt
    24841 ttgggataga agtacttcct ggatttatta ctattaaatt atcatccatg tatagctttt
    24901 ttacatgagt atgtcctaaa actaatatgt caccacccat tttctttgct ttgtcaataa
    24961 tttcttcttc tgattctata taaccatgat tcaatataat tctaatttca ccaaattggc
    25021 tcatgacata aggactctga ataggatgtt ctataaccat ctggtcaaca tctgcatcac
    25081 agttcccttt tacaatcaca atgttttcta atttatttaa tgtctcaata aattttttag
    25141 gattatatcc ttctggaata tcatttctag gtccatgata taagacatct ccaccatgta
    25201 ataaaacatc acaatcagat aatacattta acgctttttc aaagtaaagt aagctaccat
    25261 gagtatcact cattattcct attttcatat taaaaatcct cctaagtaca gtctataaaa
    25321 atttttcaga tactctatgc caaaactcat agtttgacat tctaagtaat tttatttttg
    25381 catcagatat actaactttt atattttcga tttgtctaaa tctgtgctca actccatcaa
    25441 cgacaatcaa tacagaatct tcaaatctat attctggtgc aatctttata acagattcat
    25501 ttgaacatat tatacttgat gtaaagcacc tatatgcatt ggtatttatc ggatgtaaag
    25561 gtgtaatctg cataagttca agatttatat caacaatact acctccagca gaatagttat
    25621 aggctgttga acctgtggaa gtagaaataa tcataccatc tccactaaaa ttttgtatat
    25681 gtttattatc aaggcttaaa tttaggtgta tagtcctaga cttgtctcct cttataacaa
    25741 cctcatttac agcaagcata ttagaaccac tagtagttgt atatacttcc gcattaagaa
    25801 gtgacatttc ttgaataata taatcttttt ttgtataagc ttcaataaag ctatcaatct
    25861 tatctggtaa aatatcagga aaaaacccca gatgacctgt atttattccc attatgggaa
    25921 tttcaggaaa atcgaaatct ctaactgttc ttaaaaaaga gccatcacca ccaattgata
    25981 taataagctc tgtatctgga taaatatctg aatacacttc aaagccagca ttgataagtt
    26041 ttctagttaa gagttcttta gtctcaaggg acttatttaa ttggtttgta tttatagtta
    26101 taattctttt catatattca cctcttcata ctttgtatta taacatagtt ttataattct
    26161 taatttataa atttataaat gacctttgta gtgaatgtgt taaaatatgt ataggtgggt
    26221 ataaaaaaat gcataagagg tgaagatgtg tttagcataa ggaatatcac aaaaaaatta
    26281 ggaaaattca agttaaataa tataaactta gagttaaagg aaggggatat tgttgggatt
    26341 ataggaccaa atggttcggg aaaaacgact ttaataaaaa ttataatggg gattattgat
    26401 gcagatgaag gtgaaattga actttgtaat gaaactattg aaaattctcc aataagcttt
    26461 aaaaacaata ttggttttgt atatgattct ttacaatttt atccgcattt aaaggttaag
    26521 gaatttagaa aaatagtttc tttattttat aagaattttg atagagaaag gtttgatgaa
    26581 taccttaata agtttgatat agaagaaaat atgcatattg aaaatttatc taaaggtcaa
    26641 tctgaaaagc ttatgttatc aagtgcactt agtcacaatg ctaagttatt gattttggat
    26701 gaaccaactg ctgggataga cccaattgta agaactgaaa taatgcagta cttacaagat
    26761 tttgtgaaaa atggaagtag tagtgtaata atttctactc ataatactga taatttaatt
    26821 aaaattgctg attatcttgt ttttataaat agaggaaatc agatttttac tgttaagaaa
    26881 gaattaatag aacaagaata taagataatt agggcaaata aagcagagtt agaagcaatt
    26941 aaagaaagca tagttggtgt gaaagagtat aaatattata atgaggcact tgttaaagtt
    27001 ggagatagct tgaaagtaaa aagcctattg atagaaattg ataagcataa ggtcaaaaat
    27061 cctactatag aagaactaat gtattattat gtaaatgagg tgagatgatg ttcaatttaa
    27121 taagaaaaga tttaataata gggattagtt cagatggtat ccgtaattta aagtacatat
    27181 tgctattttt tgtgttttat tttttcctta attcaatttc atattataca gtaagtattg
    27241 ttgttagtta tttgatattt ataaatacat ttgagtgtga ttatgaaaat gattcaagga
    27301 tttttataag gagtatgcca gttagtatag aagatatagt ttactcaaaa tatttattag
    27361 gtgtaggatt aataatttct gtaacaataa ttgtgtcctt actaagtaaa ttgacatcac
    27421 tagtgttctt tagaaatatg gttttaaatg atgtattttt ttctgtaaat atatttttag
    27481 caattttgac gattttactg cctttaattt ttaagtttgg atatggaaaa atgaaagttt
    27541 gtggttttat agtaagtatt ttaatttact ttgtatatgg aagtcttttg aagatgatta
    27601 gtatgattgt atatcaagta aagcatttta attatagtaa agttggagga gtatatcttt
    27661 caaattatgt aactgatata gctaatacta agtatataaa tttatatagt atgacatttt
    27721 taacaataat aatttttata atatcaatgt atttttctat taagatttca aaaaagaata
    27781 agtttaatta ttaaaatttt gattaatatt atagcacaat agcacaaaat ataaggagac
    27841 taaaaatgaa gaagtttata aaagtttcat tttttatttt ggggattttt acactattca
    27901 tagctataaa taaattagta tatagagata tggtaagtgt caaagattat gaaataaatc
    27961 atttagagga aattgttttt gattttgata gcaggagaag tagagatgtt ggtactattg
    28021 taagatttaa aataagcaat aatagtaaat atagttataa attaaacagt gctaaaatga
    28081 agtttgaaaa ttgtgtggaa aataaaaagg gaatgaataa gtgttctgca tatgtaaatg
    28141 tagatttatt taatgaaaaa aattctataa ctgaaagaac tctgaaatat ggaataaaac
    28201 caaataatca aggttatgtt gattttgtaa ttccaaaagg actaaatttt gattataggt
    28261 actttaatga atctggtatg agtgtagagt ataaaggaga atatattgtc aatattccaa
    28321 tggcaaaagg actttatcta gtagttggaa aaaataatga tacatggaat gctaatatta
    28381 tggaataatt tgaaaaataa atcaattata gatataatta agaataatat gaaatttata
    28441 aaagttcaga ctaggagggg tatttaatgt caataagtaa tgtaagagag tattttaaac
    28501 aatttggcaa ggaagacagt atattagaat ttgaacaatc tagtgctact gtggaacttg
    28561 cagctgaagc agctggggtt attccagcaa gaatagctaa gacactctca tttaaaatag
    28621 gagatgatgc aattttaatt gtgacagctg gtgatgctaa gattgataat aagaagtata
    28681 aggctgaatt taattgtaag gctaaaatgt tgacaccaga agaagtcttg gagtttactg
    28741 gacatgctat tggtggagtc tgtccatttg gtttaaaaaa ttctataaaa gtctatttag
    28801 atgattcaat gaaaagattt gatacagtat ttcctgcatg tggcagtagt aactctgcaa
    28861 tagaacttac atgtgaagaa atggagaagt tttctaagtg tgaaaaatgg gtagatgttt
    28921 gtaagaattg gtaaaaaaat atagtaaact atagtaggaa ttagtaaaaa actacctctg
    28981 tatacaatct atacagaggt agtttttttg tgtaaatatt tataaatcta agaggaaaat
    29041 ctaatttaaa ctaataatcc aaaataaagt taaaaaattc tgattttttt tcgaaacaat
    29101 aaaaaaatga caaaaaagtg gaaaaaatgt aataaatatt gttaaaaaaa taattagaaa
    29161 ttattgaaaa attatccttt gagtgatact attatagatg taagatattt aaaaataaaa
    29221 aatagtcaga taaaaatatg attatttagc tctattaaaa taatttttat acgataaaaa
    29281 tcttctgtac atggctaaaa aacagatgta cagacaatat ttaatgttta atatacctta
    29341 atataaatat cgtaaacaaa ttattttatc tctaaccagt gtgaaagaaa tcttattcta
    29401 acttgaaatt tcacaaaatt ccaaaaagcg agattttttt taagtatagt tgattttaaa
    29461 ttaacaattt atgattaaat taatgtcata attggttagt ataatcacat ataaatatag
    29521 agcgtagttt gattaaggtt ataaatttct cgacgtatat tcaaatacct tattatagat
    29581 gttgccgaga ttttaattaa taaatgaaaa taaaatattt ataaaatact gaggaggcta
    29641 ttatggattt aaattctaaa aaatatcaga tgcttaaaga gctatatgta agcttcgctg
    29701 aaaatgaagt taaaccttta gcaacagaac ttgatgaaga agaaagattt ccttatgaaa
    29761 cagtggaaaa aatggcaaaa gcaggaatga tgggtatacc atatccaaaa gaatatggtg
    29821 gagaaggtgg agacactgta ggatatataa tggcagttga agaattgtct agagtttgtg
    29881 gtactacagg agttatatta tcagctcata catctcttgg ctcatggcct atatatcaat
    29941 atggtaatga agaacaaaaa caaaaattct taagaccatt agcaagtgga gaaaaattag
    30001 gagcatttgg tcttactgag cctaatgctg gtacagatgc gtctggccaa caaacaactg
    30061 ctgttttaga cggggatgaa tacatactta atggctcaaa aatatttata acaaatgcaa
    30121 tagctggtga catatatgta gtaatggcaa tgactgataa atctaagggg aacaaaggaa
    30181 tatcagcatt tatagttgaa aaaggaactc ctgggtttag ctttggagtt aaagaaaaga
    30241 aaatgggtat aagaggttca gctacgagtg aattaatatt tgaggattgc agaataccta
    30301 aagaaaattt acttggaaaa gaaggtcaag gatttaagat agcaatgtct actcttgatg
    30361 gtggtagaat tggtatagct gcacaagctt taggtttagc acaaggtgct cttgatgaaa
    30421 ctgttaaata tgtaaaagaa agagtacaat ttggtagacc attatcaaaa ttccaaaata
    30481 cacaattcca attagctgat atggaagtta aggtacaagc ggctagacac cttgtatatc
    30541 aagcagctat aaataaagac ttaggaaaac cttatggagt agaagcagca atggcaaaat
    30601 tatttgcagc tgaaacagct atggaagtta ctacaaaagc tgtacaactt catggaggat
    30661 atggatacac tcgtgactat ccagtagaaa gaatgatgag agatgctaag ataactgaaa
    30721 tatatgaagg aactagtgaa gttcaaagaa tggttatttc aggaaaatta ttaaaataga
    30781 taaatattaa aatatacaca ataggtcgat attaaaatag atatggagga aggatttatg
    30841 aatatagtcg tttgtataaa acaagttcca gatacaacag aagttaaact agatcctaat
    30901 acaggtactt taattagaga tggagtacca agtataataa accctgatga taaagcaggt
    30961 ttagaagaag ctataaaatt aaaagaagaa atgggtgctc atgtaactgt tataacaatg
    31021 ggacctcctc aagcagatat ggctttaaaa gaagctttag caatgggtgc agatagaggt
    31081 atattattaa cagatagagc atttgcaggt gctgatactt gggcaacttc atcagcatta
    31141 gcaggagcat taaaaaatat agattttgat attataatag ctggaagaca ggcgatagat
    31201 ggagatactg cacaagttgg acctcaaata gctgaacatt taaatcttcc atcaataaca
    31261 tatgctgaag aaataaaaac tgaaggtgaa tatgtattag taaaaagaca atttgaagat
    31321 tgttgccatg acttaaaagt taaaatgcca tgccttataa caactcttaa agatatgaac
    31381 acaccaagat acatgaaagt tggaagaata tatgatgctt tcgaaaatga tgtagtagaa
    31441 acatggactg taaaagatat agaagttgac ccttctaatt taggtcttaa aggttctcca
    31501 actagtgtat ttaaatcatt tacaaaatca gttaaaccag ctggtacaat atacaatgaa
    31561 gatgcgaaaa catcagctgg aattatcata gataaattaa aagagaagta tatcatataa
    31621 tttaaggggg gataaagaat gggtaacgtt ttagtagtaa tagaacaaag agaaaatgta
    31681 attcaaactg tttctttaga attactagga aaggctacag aaatagcaaa agattatgat
    31741 acaaaagttt ctgcattact tttaggtagt aaggtagaag gtttaataga tacattagca
    31801 cactatggtg cagatgaggt aatagtagta gatgatgaag ctttagcagt gtatacaact
    31861 gaaccatata caaaagcagc ttatgaagca ataaaagcag ctgaccctat agttgtatta
    31921 tttggtgcaa cttcaatagg tagagattta gcacctagag tttctgctag aatacataca
    31981 ggtcttactg ctgactgtac aggtcttgca gtagctgaag atacaaaatt attattaatg
    32041 acaagacctg cctttggtgg aaatataatg gcaacaatag tttgtaaaga tttcagacct
    32101 caaatgtcta cagttagacc aggggttatg aagaaaaatg aacctgatga aactaaagaa
    32161 gctgtaatta accgtttcaa ggtagaattt aatgatgctg ataaattagt tcaagttgta
    32221 caagtaataa aagaagctaa aaaacaagtt aaaatagaag atgctaagat attagtttct
    32281 gctggacgtg gaatgggtgg aaaagaaaac ttagacatac tttatgaatt agctgaaatt
    32341 ataggtggag aagtttctgg ttctcgtgcc actatagatg caggttggtt agataaagca
    32401 agacaagttg gtcaaactgg taaaactgta agaccagacc tttatatagc atgtggtata
    32461 tctggagcaa tacaacatat agctggtatg gaagatgctg agtttatagt tgctataaat
    32521 aaaaatccag aagctccaat atttaaatat gctgatgttg gtatagttgg agatgttcat
    32581 aaagtgcttc cagaacttat cagtcagtta agtgttgcaa aagaaaaagg tgaagtttta
    32641 gctaactaat ttcttgggga gggtattatg agtacaagtg atgttaaagt ttatgagaat
    32701 gtagctgttg aagtagatgg aaatatatgt acagtgaaaa tgaatagacc taaagccctt
    32761 aatgcaataa attcaaagac tttagaagaa ctttatgaag tatttgtaga tattaataat
    32821 gatgaaacta ttgatgttgt aatattgaca ggggaaggaa aggcatttgt agctggagca
    32881 gatattgcat acatgaaaga tttagatgct gtagctgcta aagattttag tatcttagga
    32941 gcaaaagctt ttggagaaat agaaaatagt aaaaaagtag tgatagctgc tgtaaacgga
    33001 tttgctttag gtggaggatg tgaacttgca atggcatgtg atataagaat tgcatctgct
    33061 aaagctaaat ttggtcagcc agaagtaact cttggaataa ctccaggata tggaggaact
    33121 caaagactta caagattggt tggaatggca aaagcaaaag aattaatctt tacaggtcaa
    33181 gttataaaag ctgatgaagc tgaaaaaata gggctagtaa atagagtcgt tgagccagac
    33241 attttaatag aagaagttga gaaattagct aagataatag ctaaaaatgc tcagcttgca
    33301 gttagatact ctaaagaagc aatacaactt ggtgctcaaa ctgatataaa tactggaata
    33361 gatatagaat ctaatttatt tggtctttgt ttttcaacta aagaccaaaa agaaggaatg
    33421 tcagctttcg ttgaaaagag agaagctaac tttataaaag ggtaaaaatc taattaaaaa
    33481 tatatttgct gttaactaga ttaaatagta ttttaatcta gttaacagaa tataaatact
    33541 aaaataacag gaggttataa ctatgaaatt agctgtaata ggtagtggaa ctatgggaag
    33601 tggtattgta caaacttttg caagttgtgg acatgatgta tgtttaaaga gtagaactca
    33661 aggtgctata gataaatgtt tagctttatt agataaaaat ttaactaagt tagttactaa
    33721 gggaaaaatg gatgaagcta caaaagcaga aatattaagt catgttagtt caactactaa
    33781 ctatgaagat ttaaaagata tggatttaat aatagaagca tctgtagaag acatgaatat
    33841 aaagaaagat gttttcaagt tactagatga attatgtaaa gaagatacta tcttggcaac
    33901 aaatacttca tcattatcta taacagaaat agcttcttct actaagagac cagataaagt
    33961 tataggaatg catttcttta atccagttcc tatgatgaaa ttagttgaag ttataagtgg
    34021 tcagttaaca tcaaaagtta cttttgatac agtatttgaa ttatctaaga gtatcaataa
    34081 agtaccagta gatgtatctg aatctcctgg atttgtagta aatagaatac ttatacctat
    34141 gataaatgaa gctgttggta tatatgcaga tggtgttgca agtaaagaag aaatagatga
    34201 agctatgaaa ttaggagcaa accatccaat gggaccacta gcattaggtg atttaatcgg
    34261 attagatgtt gttttagcta taatgaacgt tttatatact gaatttggag atactaaata
    34321 tagacctcat ccacttttag ctaaaatggt tagagctaat caattaggaa gaaaaactaa
    34381 gataggattc tatgattata ataaataaga atttgggaat taaaagttta aataaaattg
    34441 tttaaaaaac aatttcggat atatgaaaaa tctaatttaa tgggggtaat gaatatgaga
    34501 gaagtagtaa ttgccagtgc agctagaaca gcagtaggaa gttttggagg agcatttaaa
    34561 tcagtttcag cggtagagtt aggggtaaca gcagctaaag aagctataaa aagagctaac
    34621 ataactccag atatgataga tgaatctctt ttagggggag tacttacagc aggtcttgga
    34681 caaaatatag caagacaaat agcattagga gcaggaatac cagtagaaaa accagctatg
    34741 actataaata tagtttgtgg ttctggatta agatctgttt caatggcatc tcaacttata
    34801 gcattaggtg atgctgatat aatgttagtt ggtggagctg aaaacatgag tatgtctcct
    34861 tatttagtac caagtgcgag atatggtgca agaatgggtg atgctgcttt tgttgattca
    34921 atgataaaag atggattatc agacatattt aataactatc acatgggtat tactgctgaa
    34981 aacatagcag agcaatggaa tataactaga gaagaacaag atgaattagc tcttgcaagt
    35041 caaaataaag ctgaaaaagc tcaagctgaa ggaaaatttg atgaagaaat agttcctgtt
    35101 gttataaaag gaagaaaagg tgacactgta gtagataaag atgaatatat taagcctggc
    35161 actacaatgg agaaacttgc taagttaaga cctgcattta aaaaagatgg aacagttact
    35221 gctggtaatg catcaggaat aaatgatggt gctgctatgc tagtagtaat ggctaaagaa
    35281 aaagctgaag aactaggaat agagcctctt gcaactatag tttcttatgg aacagctggt
    35341 gttgacccta aaataatggg atatggacca gttccagcaa ctaaaaaagc tttagaagct
    35401 gctaatatga ctattgaaga tatagattta gttgaagcta atgaggcatt tgctgcccaa
    35461 tctgtagctg taataagaga cttaaatata gatatgaata aagttaatgt taatggtgga
    35521 gcaatagcta taggacatcc aataggatgc tcaggagcaa gaatacttac tacactttta
    35581 tatgaaatga agagaagaga tgctaaaact ggtcttgcta cactttgtat aggtggagga
    35641 atgggaacta ctttaatagt taagagatag ttttagatta taatatttac aaattaaata
    35701 tttaattatg aatttaacct gtaagaataa ctatttgtta ttcttacagg tttttatagt
    35761 taaaaataat tattatctat taaacaaaaa tagtgtaaaa tatataatat catgattttg
    35821 aagatataaa aagtaggaag atataaaaga aagtaggtaa aagtttgttt aaaaaagaga
    35881 atcaaagata taatcttata tcgtatacaa atgaagaaga aatgacttta aaagaagttt
    35941 tattggacaa gctaaatttc tcagttaggt cattatcaaa aatgaagagg gaaaagagtg
    36001 ttttagtaaa tggagtatat aaaaaaccga gtttaaaggt gtatagtggt gatttaatag
    36061 aagtaaaaat agacgaggaa aaagcaaatt ttgaacctca agatttaaat ttacagataa
    36121 tttatgatga ttttgatata attatggtga ataaacctcc gtttatggta gttcacccaa
    36181 caaaaagcca ctatgataaa acaatagcaa atggtattag ttactatata gataatcaaa
    36241 aagaaaacgt aaaaataaga tttgtaaata ggttagatat gaatacttca gggttagtta
    36301 tagtagcaaa aaatgcttat gcacatcata ctttgtctac agcaatgagt gaaaataaag
    36361 ttgaaaaaaa gtatataaca gtagttgatg gaattataaa agaaaatgag ggaactatag
    36421 atgagccaat ttatagacct acagaagatt caataaagag gataatagat gaaagaggac
    36481 agtcatctgt tactcactat aaagtaatag aaagactaga aaatgcaact gtattagaag
    36541 taagcttaga aactggtaga acacatcaaa taagagtaca tatggctcat ataggtcatg
    36601 gaataatagg tgatgagttg tatggttatg tagatgaaga gctaataaat aggcaagcac
    36661 ttcatgcata taagctagag tttgaacaac caagaacaaa agaaaaattg aaatttaaag
    36721 cagatatacc agaggatatg aaagagttaa tatcgaaatt aagataatgg ggtgatatat
    36781 atgataatac ataaatttat aatacatgtt ttggacaaaa atagtgatgt tccaatatta
    36841 aatgactttg aaggcaaagt taatcaagaa gtggatggtt ttttccagaa agctataaaa
    36901 agaattgcaa aagatgagga tttaagaaaa ggtgttttta aagattataa tgacaattta
    36961 attaaaaact gttgtgaaca aataatatat gatgaaagta cttttttgaa aaattctaaa
    37021 gaaattgcat cttacttgtt tgacgttatg aaaattaatg ctgcactaga atcttgtgat
    37081 ttggcaattt gtttatacac tattaaagat gaaaagagtg tagcaatact gaaattagat
    37141 tataaaaagt tgtacactca ttcaattgaa tttgtggatg ataaatttaa tattcaaatg
    37201 gtttcaaatg aaattggtat cccagagact ttaagacaaa agcaaggagc tttgattagt
    37261 ctaagtggta taaatgatga gtttcatcta aggcttttag ataaggatgc tgaaaaagaa
    37321 gggtcagaat ctaagtttgt aacagaattt ttaaatgcta aaaaaataga tgatgataag
    37381 tacaagacca aggtatttaa aaatacagct gaaaattgga taaccaatgc tcttagtaat
    37441 gatataaagc aagctgaaga tgtaagaagt atattaaatt atacactgaa ggaaaaacat
    37501 gaagttgata taaatgactt tgttgataat tcaattaaag atgatgagtt aaaggatagc
    37561 tttaaagagc atatggaaga aaaaggtctt gacgaaagtt ttagtataga taaaaaatgg
    37621 gttgagaaaa agcttaaaaa aagaagtata aaaacggata atggttttga cataaaaggg
    37681 aatctaactg attttgaaga cccaatgaag tatactgtaa aacaaaatca agatggaact
    37741 atagatataa taataaagaa tgttacgttt tatgaagaaa agtaatttat atacttagta
    37801 tataaattaa atataagagc gtgtatttta tatattgtaa ataaatgtaa tctagtctgt
    37861 gcgaactcta atataattta ttatgtagaa gtttacacag actatttata tttgtagaca
    37921 aaacgatact atttgttttc ttcgatatat ttacatatat caccaataca tttaaagttc
    37981 tcagcttcct cgtctggtat ttctattcca aattcatctt caagggccat tataatttca
    38041 acagcatcta atgaatcagc ttctaagtcg tccattaaag atgcttccat agttatctca
    38101 tctaaattgt ctacccctaa ttgttctgct attatttctt ttattttctc aaacatttta
    38161 agcctcctaa agcagtttta attaatttta atgttagttt aatataatat caagaatttt
    38221 tcaatatgga atctataaaa aataataaaa ttttataaat gtagtaataa agtattattt
    38281 gatgaataaa ctttattgat aacaaatata acttaggagg aaatgctatg aaatatgtag
    38341 gactattact aacttcagta ggaatgtttt tacttatagc agtaaatttt tattataatt
    38401 caataacttt agatatgcaa cgtatagagg attatgtaat ggagaccaat ttaatccttg
    38461 aagatgtagc tgaaaaggag agttatgtat ctaatgaaaa agaagactac atatcaaggt
    38521 taatgcatgt aaagaaagga atagaaaatt caaaaacatc cttcttgata gaaagatata
    38581 aggagtacaa aataaaatca atagaaagtt taatctatac tatatcagag gagaaaaaag
    38641 attatctgga tgaagttgat agatacaata aacttggtga aaaagaaata aataaactaa
    38701 tcaataaaaa ctttttagaa gtaacttatc tgtctattac tacatatatt taattaaaga
    38761 gacaaaactt agtctcttaa tgattcaagg aggattagtt atgacaaaat tagaagacaa
    38821 tatggaacgt ttctttggag gatgcgaagg attttttggg aataaaatgt tgataataat
    38881 agttatagta ttcttactat tatgcacaga cattttagaa gacttattat gcgatgacaa
    38941 tatatggata tgggttatat taatagtatt gttattattt aacttcgatg atggttgttg
    39001 ttgctaaaaa atattgatta ttaaataggt aaaaccagta acttatacaa gttatggttt
    39061 tacctttttt agttcaaatt aaaaaattta aaaaaatagt aaaaatacat tagcaaaatg
    39121 gaaaccaaat gcatagtata tgttaggagc gaaaagctca acaaaatatc aacaggaggt
    39181 aacgtataat gttagataga ttctttggag aagaaggatg ttttggtgga ggaggatggt
    39241 ggataatagt actattcttc ctattcttag cttttggaga tagctgggca gaatttgaca
    39301 taatggcatg gataccattc ctaatagttt tattaatact ttgctgctgt ggtggatgct
    39361 tagaataaga acacagttat taaaaaaagg agggctttgt tatgttagat agattttttg
    39421 gagaagaagg atgctttggt ggaggaggat ggtggataat agtactattc ttcctattct
    39481 tagcttttga agattgctgg agagacattg acataatgtc atggatacct ttcttaatat
    39541 tattgctaat aacttgttca tgtggtggat tctttgatgg tgaagtaggt tgcggctgct
    39601 aatacttaaa tcattagaat aaaaaaatgc tggtatttta taccagcatt tttttatttt
    39661 attttttaat atgatttaaa ttaagaatga atattattaa atttgttgaa tatagggtat
    39721 aatataaaat ataatgtatt taaatgtact tgcttttatg gtaaaataaa aacttatata
    39781 aatgtagtta aaataggaac cttcaaaaat ttggttcagt tttagataaa tttagtaaaa
    39841 taaggaggat gaagatgaaa ggcaatataa cgataaaaga tgttgctaaa caagcaggag
    39901 tgtcaatatc tactgtatct agagttataa atgattcaaa acctgtaact gatgaagtca
    39961 aacaaaaagt tttagaggtt ataaaagaga ctggatatat accaaatcca cttgctagaa
    40021 gcttagtaac aaagaagagt caattaatag gggtaatagt tccagaagtt tcagattctt
    40081 ttgttaatga ggtgttaaat gggatagaag aggttgctaa aatgtatgac tatgatattc
    40141 ttttagcgaa tacatactct gataaggaac aagaacttaa gagtataaat ctattgagag
    40201 caaaacaagt ggaaggtata gttatgattt catggatagt tgaacaagaa catatcaact
    40261 atatacaaaa ttgtggaata ccagcgacat atataagtaa aactgctaga aattatgata
    40321 tatatacagt aagtactagc aacgaagaag ctacttttga tatgacagag catcttataa
    40381 agaaaggtca tgaaaagata gcttttataa tgacgagtaa agatgatact gttttagaaa
    40441 tggaaagact tgctggttat gagaaagcac tttcaaataa caatatagaa ttagacaaga
    40501 gtttgattaa gtatggtgga actgattatg agagtggata caatagtatg aaagaactat
    40561 tagatgatgg aataatacct catgcggctt ttgtaacagg tgatgaggct gccataggtg
    40621 ctataaatgc tatatgtgat gctggatata aggttccaga agacatatct gttgcaggat
    40681 ttaatgatgt taagatagct agaatgtata gacctaaact tactacagta tatcaacctc
    40741 tatacgatat gggagcagta gcaataagaa tggttataaa gttaataaat aaggaattaa
    40801 ttgagaataa gaaaatagaa ttaccttata gaattgttga tagagaaagt gttacagaaa
    40861 gaaaaaaata aaactattaa aatcaatcag gtagtgccta aggcactacc tgatttttta
    40921 tgtcaataat atcaaattta ataatagatt aactaaaaat aattatctaa ttacttaaat
    40981 agtttatttt tatctattca tgagggttag actttttagt tttcttaaat aaacttttag
    41041 attttttttg ttgactacct ggtgtatttt ttggtgcagg tgaatttgac ttacctttag
    41101 taggtttagc cttcttagtt ttagctggtt tagtatctct ttggttttct gcatctgaga
    41161 ttttttccat tatattatcc agttttttgc gttgattttc atctaaaaat gctttgaatt
    41221 ttgatactac ttcatctctg ccatctaggt tcttacctat ttttataagt tcctccataa
    41281 gttcattttc tgattttcct ttgtaactat cagccatctt ttctatttta tccttgtcaa
    41341 tatttttttg tttagccatt ttttctaatg actctgtatc taattttttc ataaaaaaac
    41401 ccctttctat aaatatatat tgaattatat tcatactatt tatatataga aataatattg
    41461 aagtggtgaa ttgtgagtga tatataatat aaataaaaat tcttatagat aatatatatg
    41521 cactgagctt taaaaatgga acattaaaat atgaaaaaca tactttaata tagggcaatt
    41581 atataatata agggggaatt gtcttgaata acttactatt tttgattgga gtgattgcat
    41641 tgagtaatgg taatatctct atatttgatg ataaaaataa atcaaaagga aataatagag
    41701 ttagaaaaaa caaaaaaaat gcaaatgata aactttcaca gtctacacat ggcaatttaa
    41761 ggtttgatgc aaatgatata aaaagaggtt taaggctcat ggatttaagt gaagaagatt
    41821 tagaaatggg aatggaaata ataacaagaa ctaaaaaata catgtcaaga gatgaaagaa
    41881 aaatactaat aaaaatagaa agtgttttag atttagttag aggaataaaa aaattaaata
    41941 atatagatat ggtagataca gaagatgaaa cggatttttt cagaaaaatg gatagtgatg
    42001 ataaaaagaa tatgatgata aaggaaatta tagatgtatt cccagaaaaa agaaaaaatt
    42061 cagttgaaaa agctatagga atgaaaaaga agatagattt atttgcagaa ttatttttac
    42121 cagatgactt tggtgaaggt ggatttagtt tgagctcttt ggcaaatata aacaatcttg
    42181 gtagtatgaa taatctcaaa ttgttaggaa gtcttttaag aggtgatgat agtaataatg
    42241 atgatgaaga caataatgat gagttaaatt atgaagacga agaattagat tgtgaagaca
    42301 aagaattgga tgatgattat gatgagttaa cagacgaagg tgaaatggag gataatgaag
    42361 atgaattagt agaagataag aacacaggct atgaaaatat agaaaatgat gaagatatag
    42421 tatatgatga ggaactatac aacattaatg agcaagaatc cgaatacaat tataatgaaa
    42481 aaaatactaa aactagagct aagaaaaaac gataattaac taaatacata aagaaaaaag
    42541 gaagaaaaag taatgataga ataagattat ctcaattact atataaaacc actttaaaaa
    42601 attcaaaatt tattatataa taataatatg aaatcctgaa acatacgata aggctttttt
    42661 aaattcaacc tacaaatgaa atacgggaga ccgtgtctgg taaattataa catgcctagt
    42721 tagtttggac gttaaaggtt actggcaagt cacccacctg ggagtgccta gggtgtgaat
    42781 ttacttagcc accggtgttt cgggacaaaa aaagtgctac tatttcaaat agtagtactt
    42841 tttttattaa tatgcatttt tctactaaat acgcctaatt attgataaat tcaaaaagca
    42901 agtaacaatt aagattataa aagcatagta ttaattaggc ttcaaaaagc caaagactta
    42961 ataagaatcg cttacaggga gggcaatgaa aaatgcaaga ttataaaaaa aataaaagaa
    43021 gaatgatgaa tcagccaatg tctacaatga atgaagaaga agtgtataca gatgaaataa
    43081 attcagaaga catgagaggt tttaaaaaat cacaccatca taatggatgt aatactgata
    43141 ataagtgtga gtgccatgat gattgcaatc catgcaaccc atgtaatcca tgtaaaccta
    43201 acccatgcaa tccatgcaaa cctaatccat gtgatgacaa ttgtggatgc catgacaatt
    43261 gtaaatgtga ttgtgaacca tgtgaaatgg attcagatga atgttttgaa aacaaatgtg
    43321 gaccagaatg ctgtaatcct atatctccaa gaaacttctc tgtatcaaat gcagtgccat
    43381 ttgcaataga ggctaataga atatttgata ctatgcaatt ccaaacattt acagatgcaa
    43441 caggaccaaa tggagagcca ttaacttttg aaacagaagt agtagaagta tttggttcag
    43501 ttccaagtgc aggtcaagca agtgtaacta tagaaaaaat atgcttaagt aatgatggaa
    43561 tcgttataga cacaggaatg acaactttag aagatttcga tttagaccca ttaggagata
    43621 tagtaggaag aaactgtgaa acaacttttg aatttgcagt ttgtggagaa agaaacgctg
    43681 agtgctgtag acaaggaaaa ggcaaatcag tagcttataa acaaagagga ttaactgtag
    43741 cagttcgtaa tttagtacta gagctaagag gtagatgtgg atgtacagag ttcgttgcat
    43801 tagctttccc agcagttaga gcaggaggtg gatgtaagag aagagttgat tatgtagaat
    43861 ttacttttaa cacactttca gcaccaatat gcttgccagc tgacggaaga gctgttactt
    43921 taagacaaga atatcaaact aacttaactg tagattgtat aggaaaatct atattaaaat
    43981 tagaatgcaa cgaatgttgt gaacctttct atgaattaat tataccaaat gatatagatt
    44041 tagtactttg cttacaagaa acagttagca cattaataag tgaacaaata gtagttttag
    44101 catcaccaaa tccaatccaa ccaagacttg ttgatacttt ctctaaagta tgtgattttt
    44161 cgcaatgtgg acctaatcat ggaagtggaa agccaagttg ccacagatag ataggtaaga
    44221 tatatagaca gtttaaatta taaataaaaa tcatctaagg aaggctacca aagtgtataa
    44281 tttacattgg tagccttcac gtttttataa ctagcgtata gattttagtg atttaaaaag
    44341 cactatagta tgtaatagac aagtaaagat tgatactatc gtcattgtgt atatgtatgc
    44401 ataaatatta agtcctggaa ttggaagaaa tacatataaa gctattagtt gaattaacat
    44461 gccagtaata gtatttatac ttgaagctaa ttcttttctt attgaatgta aaatgccaga
    44521 tagagtttga tttagggaca taaatagtgg aactaaaaac atagctttta gatattctcc
    44581 tgcaagtgta tttttaaata ctaatataca taaatctttt ccaaagaaat aaaaaaatat
    44641 tgatgatagt atgcctacaa ataaagtaag aagtatggag tatttgattt ttttaattac
    44701 actcttacgc tttcttagag ccatttcttg tgaaatagtt ggtattaaat ttacaataag
    44761 cgctgaacca acagtaaaag gtaaaaatat aaaaggcatt accatcccac tgacaatacc
    44821 atacatactt aaagattgtt gataagtcat tcctgataat gctaatcttg atggtatcat
    44881 catagaactt atagattgca aaagtatgtt tgacattcta ttacaagtta tgggaataga
    44941 catttttaat gtttccatag aagaattata aaaatctttt atgcttataa tatacctatt
    45001 gtcaaatgat gaatctcgcc ataagcaaat aagcataaat ataatattac tcaactcacc
    45061 gattgatata cctaatagag ctatataaca attcatagat ttattattta tgtacataac
    45121 tagtaaaaaa acaaataata ttttaccaat ttgttcaatg atttgtccaa tagcagggat
    45181 ttttacattc tttatgccat agtaatatcc tcttagtacg tttgaaagag ttattataac
    45241 tatagcagga caaacagcta gtataaatag atttaattta gcatctttta aaaatttaag
    45301 tgataaaaaa gaactattga aagatgcaac tatagatata attagtgcta cgaaaaatga
    45361 tatatataaa gttgatataa ataaagcatt agtattgtgt ctatcgttta aagcttttct
    45421 ctttgcaact agacaactaa gtgcagtagg tatacctgtt gttgtaacag ctaagcaaat
    45481 catcaaaaag ttaaaaatca tatgatagat acctaaacct gtttcaccta gtgctcttga
    45541 taagaatatt ttatataaaa aaccaaatat tcttacaata aaattggata taaataaaat
    45601 aactgttgat agtactaaat aaggtacttt caaaaaaatc acctccttat cttttaaata
    45661 tattcacaag gaggtgtaaa aatttataat tttataaatt ctggtttcaa tttattaaat
    45721 ttagatacat atttaaatcc catatttttt agtaatgaat atatgtagtc aaactcacat
    45781 gcaacttgac ttatatgatg tgaatctgaa cctgtggtta tgatttcccc tcccaagtct
    45841 ttatacattt gaagtatata cttagatggg gttaggtctg gaagattata tctataacaa
    45901 gaggtattta tctcgatacc tttgccatca taaatagctt gtttaagagt ttcttcaatt
    45961 atatcagaaa atagtctatc atctaaaata gtgtcataag gtgcatacct tttaatcaaa
    46021 tctaaatgac ctaagacaga gtaatcttta taattcttaa caatattata taaataaaga
    46081 tagtaatttt cataaacttc atgttgagtt ttatctttaa aataattacc aaggtataag
    46141 tccattgtat ctatagcatg gatagaacat attataaagt ccaatggata ttgatgtgct
    46201 tcctttttgt atgtatccat taattgagtt tgaactccaa attcaattcc tttttttatt
    46261 gatattttat ctttatattt gctttgaaga gtctctaaac tcttaaaata atcttcgtag
    46321 acaattgaaa aagaatcatc agcatataca tcatagtcaa catggtctgt gaaacaaatt
    46381 tcctccaaac cgagttcaat agattttttt accatttctt ccattgtaga ttttccgtct
    46441 gtagagaaac ttgagtgcat gtgatagtcg taaaacataa atatttcccc tttttataaa
    46501 aattttggta ttatatatac atactaaata atatcaaata tacataaaag catcaataaa
    46561 atataaatac aatgagcggt gataaatttg gaaaaataca gaatagattt aaatgagaaa
    46621 aaatcaacta aatatataca gatatttaat catataaaag aattgataat aaataaagag
    46681 ttagtagaac atgaaaaatt gcctccaata agaaaactat caaatttttt acaagtaaat
    46741 aacactacta tagttaaggt atacgagctt ttagaaaatg aaggatatgt atataaaatt
    46801 atagggagtg gtacttttgt atcaagttta aattcttata aaagcggtat agataacagg
    46861 aaaaataaga ttattgtgca aagagaagat ttaattcatt ttgacaatgg gaatccatct
    46921 aatgatatgt ttcctatcga ttcatttaaa aatgctgtaa atatggcatt atctaaagat
    46981 ggtagttcaa tatttgaata tgatgaaggt cttggctctg aagaattaag agaaaaaatg
    47041 gtagagtatc taagtgatgg aaatataaaa actactaagg aaaatattca aataatatca
    47101 ggtgctcaac aaggtataga tatagtttgt aaaggactta taagttattc agatgttgtt
    47161 tttatggaag aaccttctta caatggagca attgaagtgt ttaaaagtag aggtgcaaaa
    47221 ataatatcta tacctatgtt agatgatgga attgatatag gtattttaaa attaaagttg
    47281 gaaaaaataa aaccaagact tatatacatt atgcctaatt ttcaaaatcc aactggaata
    47341 tcttactcaa catataaaaa aaagaaattg atagaattgg cagaagaaca tgatttttat
    47401 ataatagaag atgattttat aagtgatttt gtttttgaat caaaggacaa tagaacaatt
    47461 agaagttatg atgataaaaa tagagtagta tatataaaaa gcttttcaaa aatacttatg
    47521 ccaggtctta ggataggaat tgtagaaatg ccaaatgagt tgttaaaaaa agttttatgg
    47581 gctaaatatt catcagatat atcaacacca ggtttaattc aaaaatcaat gtattactat
    47641 atgaataatt ttgattggaa gaattatttg agtcatatag aaaagatata tactgataag
    47701 tataaattgg caaaaaactt gattaatgac aaattgagtg gtaaattaaa agttagaaaa
    47761 tcttgtggag gaataaactt ttttttagaa ttaccaagag gatatacatc tcaagcattt
    47821 acaaatttta tgttaaacaa aggagtgtca atgcttccag ggacttattt ttttgacaat
    47881 ctagtggatg atagattctt taggataaat atagctcgcc caagcatgga agaactagaa
    47941 aagggaatat ctataataag tgataatata gatgagtttt tttgtgaata taaaaacaag
    48001 ttagatataa aaagcaataa attattttat taaataaata gaggtttttt aggaggaaaa
    48061 aatgtttgac aagaagaaat tagataggat taatgaatta gcaaagaaaa ataaagaggg
    48121 aatcctttct gctgatgaaa tcaaagaaag agaaatttta aggaaagaat atttagaaaa
    48181 ctttagagcc cactttagat caagactaga tagtgtcaaa gtagtttcac cagaagaata
    48241 tgagcaatac atgaaaaaca ataaaaatta gaacttagta ggaggaaaat atgaacttaa
    48301 agtacgaatt taagaatgct tgggattttg aaagaaaaga aaatactatt gaacaaatta
    48361 tgcaatattc tagcaattat atggagtttt taagtaagtc aaagactgaa agactttcag
    48421 taaaagaaat tataaaattg gctaaagaaa ataactatat ttcaatagat gaagctatgg
    48481 aaaaaggaag cataagttgt ggtgataaga tttatgttat aaataaagag aaggcagtag
    48541 cactttttgt aataggtaaa aattatatag aaaaaggtat gaagattata ggaagccata
    48601 tagattcgcc aagattagat ttaaaaccaa atccactgta tcaagagagt aatctaggtt
    48661 tttttaagac tcattattat ggtggaataa aaaaatacca atggacggct attccacttg
    48721 ctttacatgg tatagttata ttaaatgatg gaacaaaagt ggacatatct attggggaag
    48781 aagatagtga cccagtattt tgtgtaactg atttattgat tcatttggct ggagaccaaa
    48841 tgcaaaagaa actatcagaa ggaattagtg gagaagcttt aaatatatta attggaaata
    48901 tgcctttaga agatgaagaa aaagaaccta taacagcaaa tatattaaag attttaaatg
    48961 agaaatacaa tatagttgaa gaagatttat taagtgctga aattgaagta gttccagctg
    49021 gtaaggctag agatttaggg cttgataggt ctatggtgtt gggatatggg catgatgata
    49081 gggtatgttc atatgctgct gtaaaagcta tactagaaac tgaacaacca gaatttactt
    49141 cagttgcatt atgtgtagat aaagaagaaa ttggttctaa agggaataca ggtatgcact
    49201 caaagttttt tgaaaatact gtggctgaac tgattgcttt agaaggagat tattgtgata
    49261 ttaaagtaag aagagcttta gcaaatagta aggtattatc agctgatgtt tctgctggat
    49321 atgacccaaa ttttggagaa gcatatgaaa agagaaattc ggcatatatg ggaaatggag
    49381 tagttttaac taagtataca ggttcaagag gaaagagtgg atgtaatgat gctaatgctg
    49441 aatttatgtc agaagtaaag agaattttta ataaaggaaa tgtaatatgg caaactgctg
    49501 aacttggaaa agtagaccaa ggaggaggcg gaactatagc ccatatattg gcaaatcaag
    49561 gtgcagaggt tatagactgt ggtgttggag ttttaaatat gcatgcacca catgagattg
    49621 tctctaaagt agacatatat gaaatgtata agggatataa ggcatttttt aatataaatt
    49681 tataagtaaa aatataaatg taataagtga ataaaggctg ttgtataaac aatttaatct
    49741 gttgtacaac agtcttattt ttatgtaaaa atagcaattt gtcacactag agaaaataaa
    49801 agaaaatact gtcaaattaa aaattattta aaaaaaaatt gacaacgatt tcatcttgtt
    49861 ataatatgta ataaagaact tgttatataa tgttataaaa atgttacata gggaggtgag
    49921 caaaatggat gaaaagagac aaaaaaaaga aatggattta gaagtaaatt cctttgttcc
    49981 tttatatcaa caactatatg acaacataaa aaaacaaata gcatctggca tatataaacc
    50041 aggagataaa cttccatctg aaggagactt atgtaaagaa tttaatataa gtcgtataac
    50101 tgtgagaaat gcacttaatg aacttgtaaa agaagatata ttatgtaaaa aacgtggtaa
    50161 agggacttat gtaacaatac cagagagaat agaagcaaca tgtgcaggaa atagttttac
    50221 taattcttgt catcgtatta atgcaaaacc aagtaccaaa ataatctctg ttttaataaa
    50281 aaaagcagat aagcaagtag ctgaagcttt aagtattgaa ctagaagaga aggtaatatg
    50341 tattaaaaga cttagattaa tagatgaagt acctgttatt tttgaagttg actattttag
    50401 aatagattac atgtttttat taaaagaaga attagaagat aaatctttaa tggaggttat
    50461 atctaataat ataagcacat tacctaaacg agtagaaaat atatttgaag taaaacattc
    50521 aaacaaagaa tattctgacc atcttaaatg tgcaagtaat atgccactat tgaaagtaag
    50581 acaatcggtg tatacagaaa ataatgatgt cttatattac aatgagcaat ttataagaag
    50641 tgataagtac aaatatgcag tatcagcaga aatataatct ataatttagt aggaggatga
    50701 gtatgaaaaa gataatatta gcatctcatg gagacttttc aaaagggctt ttaaatgcag
    50761 taaaaatgat agtaggagat ttagcagatt gtgtcagttc gtatggtttg taccctggac
    50821 aaagtgcttc agattttgct ttagaattag aaaaaacaat atcagaagat aaagaatgtg
    50881 aatatataat tttatctgac ttatatggag caagtgtatg tacagcaatg ttaagattaa
    50941 ctaatctaca taatgttagg ttattttctg gaatgaattt gaatatggta ttagaacttc
    51001 ttacaaggtt ttctgatgaa ttaacagttg aagatataga ccaattagtg gaagaatcta
    51061 gaagaggaat acaaagcgtg acattacaaa ttaaagaaga agaagaggta ttttagttta
    51121 tgaaaaaaaa gggaatatta tcagtattta aaagtaaaaa accaattata gcaatgatac
    51181 acttaaaagg agatactcca gaagatatct ttgaaagagc taaaaaagag attacaatct
    51241 ttgaagaaaa tggtgtagat ggaataatgt tagaaaatta ctatggtaat tattatgatt
    51301 tagaaagaat acttgaatat gtatcaaaag ctaatttatc aataccatat ggagtaaact
    51361 gtttaaatgt tgatactatg ggatttgaac tggcaacaaa atataatgct agttatatac
    51421 aggttgattc tgtagtaggt catgttaaac ctagagatga agctacttta gaagagtttt
    51481 ttaaattaca acgttcaaaa tgtccagcgt atttaattgg aggcgtacgt tttaaatatc
    51541 agccagtatt atcagaaaat gatgttgaag aagatttaaa aataggaatg acaagatgtg
    51601 atgctatagc agttacagaa aatgctacag gtcaagaaac atcaatggaa aaaatagaac
    51661 tgtttcgtaa aaatttagga gacttcccat tggttatagc tgctggagtt acattagaaa
    51721 atgcaaaaaa acagcttaaa ttaggagata tggcaataat aggaagttac tttaaagata
    51781 attacaaaga ttttggggat gttagtgtag aacacgtaaa aacattcatg gatgaaatca
    51841 aaaaaattag ggaggaatta taatgattaa attagtaaga gtagaccaca gacttataca
    51901 tggacaagta gcatttacat ggacaaagtt tttaagtaca gactgtatat tgatagcaag
    51961 tgatgactta ttaaaagatg aattaagaat ggcaggactt aaaatggcta aaccatctaa
    52021 tgttaagtta gtaatgaaaa gcatagcaga ttctataaaa gcacttaact caggtgttac
    52081 tgataaatac aacttattga tactttgtga atctgtagaa gatgtttaca gacttgctaa
    52141 agaggtaaaa gctattaaat ctataaacct tggtggaaca aaatcagatg ataatcgtga
    52201 aaatatatct aaagcagtgc atgtatcaaa agatgatata aagatgatta aagagttaga
    52261 ttcagaaggc gtaaatgtat ttgtacaatt agttcctgat gatgatgcta caaatgtaat
    52321 gaaattaata taattttagg gggatgaaaa tggaatttac acaagttatt ttgataactc
    52381 taattgcatt ctttgcatat atgcatagtt ttgtaggttc tacaatgcat aatagaccta
    52441 tagttgttgc accacttgtt ggtttagcac taggtaatct tcatacaggt atagtaatag
    52501 gttcaacatt agaattagta tttatgggtg catttcctgt tggggcaagt aatcctcctg
    52561 attttgtgtc tggttctatt attgccacag cgtttgtaat attaacgggt caagatgtat
    52621 cagcagcagt tgtacttgca gttcctatag caactctagt attgcttata gataacttct
    52681 taatgacagt agtacttaca tggggagctc atattgctga ccgttatgca gaagagggga
    52741 atattgaagg cgtagaacgt gtgcaattat tatttggtat aggaaataaa ttaatattag
    52801 caataatagt aggtatagga ttttcattag gtgttccagt aatagaaaaa atactttcat
    52861 ttataccatc atatgtaact catggaatgg atgttgcagc aggcgtgatt ccagcaatag
    52921 gttttgccat gttagctaga atgatgctta ataagaaaac agtagcattt ttattattag
    52981 gatttatatt ggttgcttac ctaaacataa cagtaacagg agttgcattg tttggattag
    53041 caatagcttt aatatatgtt aactttgtag gagagaagga ggtaatagta gatgacaacg
    53101 agttctaaga aattagagac aatttcacca gatagtaaaa taacgaggaa agacttttgg
    53161 aaatgtttta gaaggtcatt gacattagat tcatcttgga actacgaacg tatgcaaaat
    53221 atagcatatg catacatgat ggcaccaata atccgtagat tatataaaga tgataaagaa
    53281 aagaaatcta aggctttaaa aagacattta gaatttatgt cagttactcc tcatataagt
    53341 actcttttgg taggtatatc tggagctatg gaagaagaaa atgcaaagaa taaagaattt
    53401 gatgctaata gtataaatgc tgttaaatca agtttaatgg gtccagtttc tgggatagga
    53461 gattcatttt tctggggaac attaaagctt atagcagctg gggttggtat agctttagct
    53521 tctcagggta acataatggg accgatttta ttccttttaa taataaatgt tcctcatttt
    53581 attatacgct atatatgtct agataaagga tttaagtatg gaactcaatt ctttaaagat
    53641 gtgagtggtt caagtatagt ttcaaaagtt atggaagcag cttcaatgtt agggcttatg
    53701 gtaattggag gtatgactgc atctaatgta atgttaaaac ttagtgttaa tgtaggtagt
    53761 ggagaatggg cagagcctat tcaaacttac ttagaccaaa taatgccatg tatgcttcca
    53821 gctatgatat tcggtattat gtattggtta ttaggaaaaa aggtaaagac aactacgata
    53881 ttaatttcag ttatgattat ttgtatagta ttggctgcta ttggagtagt ataaataaaa
    53941 aaatcccaag ttcatttgaa cgagggattt tttgactaaa ttaaataaaa aagaaagatg
    54001 gttcataata atttataagc atttatgtga tagttataat tagcttatta attagttata
    54061 aactcaaaat taagcactac tttattaaag ttattatatt ataatttcga aatactcaca
    54121 taatctgttt agaaatttat cttctaatgg ggaaaaagtt ttctttttag agtaaatgaa
    54181 gaaaaacttt ctagtaaaat caacatcctt tattttataa cattttattt tacctgcatt
    54241 gagataatcg atagctgaaa tgtacgatat aaaggacact ccaagaccta atctaaccat
    54301 ttccttaata gcctcatttg attctacatg agcgattaca tttaatttac ttactggaaa
    54361 gttattttta ctaagtgtgt ttagtattaa gtttcttgta cctgaccctt cttttctcat
    54421 aataaaattt agataagcca attctcctat atcgatacaa ttatttttat tatcaatttt
    54481 aaaatctgaa ggagtgataa gaacaagttc atcatctaat aagtctaggt actctatttg
    54541 aggattattg attttagaac caactaatcc aaagcttatt cgttcattta aaatttctga
    54601 tatagcatat tgagaatcat aatggcttat ggaaaatttt acatctggat aactcataga
    54661 aaaactcttc ataaaatcag gtaaaatata agtttcaggt atggaactac atgctatatc
    54721 tataatacct tctatttttc ctgaatattc ttttatatca taaattgcac gtttgcaatt
    54781 attcaatata tatatagcat gttcataaag aatttcacca gattttgtga gtgtaataac
    54841 tttgttgctt ctatttataa gaacagtttc tagctctctc tctaaattct gtatgtgtgc
    54901 gcttacagta ggttgagtta aaaaaagttc tcttgcagcc tttgaaaaac tctgatgttt
    54961 tgcaacagca acaaatactt caagttgttt aaaatccatt atttaatcct ccttaaatta
    55021 tctaaaacta ttataacata tttgataaat taatagtcaa aggtgatttt taaaatagaa
    55081 aacctttaaa tattcatgga gtttttgatt gtttaggaat aatttggtat aatgttgtaa
    55141 ggtacttaca ataaaaatat cgtaaattga attttcaaaa ttcaacttta aagtgttttt
    55201 tattacagaa aaattacaat tagcttctta atcttattaa attcaaataa atattata
//
LOCUS       DAEHWO010000017        53272 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEHWO010000017 DAEHWO010000000
VERSION     DAEHWO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53272
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.017"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(83..1111)
                     /locus_tag="KNP54_001294"
     CDS             complement(83..1111)
                     /locus_tag="KNP54_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBF0892200.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVVYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            complement(1159..2019)
                     /locus_tag="KNP54_001295"
     CDS             complement(1159..2019)
                     /locus_tag="KNP54_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBF0892201.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2288..2497
                     /locus_tag="KNP54_001296"
     CDS             2288..2497
                     /locus_tag="KNP54_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBF0892202.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2497..2763
                     /locus_tag="KNP54_001297"
     CDS             2497..2763
                     /locus_tag="KNP54_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBF0892203.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2792..3364
                     /locus_tag="KNP54_001298"
     CDS             2792..3364
                     /locus_tag="KNP54_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBF0892204.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3599..4789)
                     /locus_tag="KNP54_001299"
     CDS             complement(3599..4789)
                     /locus_tag="KNP54_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBF0892205.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(5049..5480)
                     /gene="dut"
                     /locus_tag="KNP54_001300"
     CDS             complement(5049..5480)
                     /gene="dut"
                     /locus_tag="KNP54_001300"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBF0892206.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5593..7821
                     /locus_tag="KNP54_001301"
     CDS             5593..7821
                     /locus_tag="KNP54_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBF0892207.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7932..8417)
                     /locus_tag="KNP54_001302"
     CDS             complement(7932..8417)
                     /locus_tag="KNP54_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0892208.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8669..9892
                     /locus_tag="KNP54_001303"
     CDS             8669..9892
                     /locus_tag="KNP54_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBF0892209.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPSILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9896..13030
                     /locus_tag="KNP54_001304"
     CDS             9896..13030
                     /locus_tag="KNP54_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBF0892210.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            13064..14362
                     /locus_tag="KNP54_001305"
     CDS             13064..14362
                     /locus_tag="KNP54_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBF0892211.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLTDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14651..14896)
                     /locus_tag="KNP54_001306"
     CDS             complement(14651..14896)
                     /locus_tag="KNP54_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBF0892212.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(15110..17737)
                     /locus_tag="KNP54_001307"
     CDS             complement(15110..17737)
                     /locus_tag="KNP54_001307"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBF0892213.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17798..18640)
                     /locus_tag="KNP54_001308"
     CDS             complement(17798..18640)
                     /locus_tag="KNP54_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBF0892214.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18647..19285)
                     /locus_tag="KNP54_001309"
     CDS             complement(18647..19285)
                     /locus_tag="KNP54_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892215.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19721..21013)
                     /locus_tag="KNP54_001310"
     CDS             complement(19721..21013)
                     /locus_tag="KNP54_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBF0892216.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDIDLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(21050..21406)
                     /locus_tag="KNP54_001311"
     CDS             complement(21050..21406)
                     /locus_tag="KNP54_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBF0892217.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21441..21800)
                     /locus_tag="KNP54_001312"
     CDS             complement(21441..21800)
                     /locus_tag="KNP54_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892218.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAVISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21869..23842)
                     /locus_tag="KNP54_001313"
     CDS             complement(21869..23842)
                     /locus_tag="KNP54_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBF0892219.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFD
                     KGLLFPHSINEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(24064..25077)
                     /locus_tag="KNP54_001314"
     CDS             complement(24064..25077)
                     /locus_tag="KNP54_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBF0892220.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(25090..25635)
                     /locus_tag="KNP54_001315"
     CDS             complement(25090..25635)
                     /locus_tag="KNP54_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBF0892221.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            complement(26011..26880)
                     /locus_tag="KNP54_001316"
     CDS             complement(26011..26880)
                     /locus_tag="KNP54_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0892222.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSRRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            complement(27032..28147)
                     /locus_tag="KNP54_001317"
     CDS             complement(27032..28147)
                     /locus_tag="KNP54_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBF0892223.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            complement(28383..29519)
                     /locus_tag="KNP54_001318"
     CDS             complement(28383..29519)
                     /locus_tag="KNP54_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0892224.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            complement(29575..31038)
                     /locus_tag="KNP54_001319"
     CDS             complement(29575..31038)
                     /locus_tag="KNP54_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBF0892225.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            complement(31683..32942)
                     /locus_tag="KNP54_001320"
     CDS             complement(31683..32942)
                     /locus_tag="KNP54_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0892226.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            complement(32966..34174)
                     /locus_tag="KNP54_001321"
     CDS             complement(32966..34174)
                     /locus_tag="KNP54_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBF0892227.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            complement(34204..35097)
                     /locus_tag="KNP54_001322"
     CDS             complement(34204..35097)
                     /locus_tag="KNP54_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBF0892228.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            complement(35115..36173)
                     /gene="buk"
                     /locus_tag="KNP54_001323"
     CDS             complement(35115..36173)
                     /gene="buk"
                     /locus_tag="KNP54_001323"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBF0892229.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            complement(36330..36869)
                     /locus_tag="KNP54_001324"
     CDS             complement(36330..36869)
                     /locus_tag="KNP54_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBF0892230.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            complement(36882..37601)
                     /locus_tag="KNP54_001325"
     CDS             complement(36882..37601)
                     /locus_tag="KNP54_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBF0892231.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            complement(37604..38680)
                     /gene="vorB"
                     /locus_tag="KNP54_001326"
     CDS             complement(37604..38680)
                     /gene="vorB"
                     /locus_tag="KNP54_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBF0892232.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            complement(38709..38906)
                     /locus_tag="KNP54_001327"
     CDS             complement(38709..38906)
                     /locus_tag="KNP54_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0892233.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            complement(39189..39956)
                     /locus_tag="KNP54_001328"
     CDS             complement(39189..39956)
                     /locus_tag="KNP54_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBF0892234.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            40236..41783
                     /locus_tag="KNP54_001329"
     CDS             40236..41783
                     /locus_tag="KNP54_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBF0892235.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEKLFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     IENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNKEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            complement(41949..44015)
                     /locus_tag="KNP54_001330"
     CDS             complement(41949..44015)
                     /locus_tag="KNP54_001330"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBF0892236.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(44015..44893)
                     /gene="glyQ"
                     /locus_tag="KNP54_001331"
     CDS             complement(44015..44893)
                     /gene="glyQ"
                     /locus_tag="KNP54_001331"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBF0892237.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            complement(45053..45652)
                     /locus_tag="KNP54_001332"
     CDS             complement(45053..45652)
                     /locus_tag="KNP54_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBF0892238.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            complement(45645..46418)
                     /gene="recO"
                     /locus_tag="KNP54_001333"
     CDS             complement(45645..46418)
                     /gene="recO"
                     /locus_tag="KNP54_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBF0892239.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            complement(46384..46539)
                     /locus_tag="KNP54_001334"
     CDS             complement(46384..46539)
                     /locus_tag="KNP54_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBF0892240.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            complement(46612..47991)
                     /gene="mgtE"
                     /locus_tag="KNP54_001335"
     CDS             complement(46612..47991)
                     /gene="mgtE"
                     /locus_tag="KNP54_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBF0892241.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            complement(48003..48896)
                     /gene="era"
                     /locus_tag="KNP54_001336"
     CDS             complement(48003..48896)
                     /gene="era"
                     /locus_tag="KNP54_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBF0892242.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            complement(48960..49361)
                     /locus_tag="KNP54_001337"
     CDS             complement(48960..49361)
                     /locus_tag="KNP54_001337"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBF0892243.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            complement(49480..50199)
                     /locus_tag="KNP54_001338"
     CDS             complement(49480..50199)
                     /locus_tag="KNP54_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBF0892244.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            complement(50205..50666)
                     /gene="ybeY"
                     /locus_tag="KNP54_001339"
     CDS             complement(50205..50666)
                     /gene="ybeY"
                     /locus_tag="KNP54_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBF0892245.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            complement(50723..51838)
                     /locus_tag="KNP54_001340"
     CDS             complement(50723..51838)
                     /locus_tag="KNP54_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBF0892246.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            complement(51777..53120)
                     /gene="yqfD"
                     /locus_tag="KNP54_001341"
     CDS             complement(51777..53120)
                     /gene="yqfD"
                     /locus_tag="KNP54_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBF0892247.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            complement(53133..>53272)
                     /locus_tag="KNP54_001342"
     CDS             complement(53133..>53272)
                     /locus_tag="KNP54_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBF0892248.1"
                     /translation="YEVDLIRIKTKVKTIKISGDKLSLKYITDSEIGIKGIIYNVEYV
                     D"
BASE COUNT        17485 a         9405 c         6229 g        20153 t
ORIGIN      
        1 tatattaatt taattttatc ttgattcagt tttataaaaa attgttataa ttgtcaagtt
       61 ctactctatt atttataatt tcttatatct tattaacaac atttaggtta ttacatttat
      121 ttatatatat tttttcatta tctaagtctt catcaaacat ttttattata ttttttatct
      181 catacttgta ctcatcttca ttcattctat aaagcattaa atcttctagt acatctttca
      241 tgtcgaagta cacatcttct aataaataaa aatagccttc ctctatatct ttcaatttat
      301 ctatagtatc cattttttta cttatatctt tcataatttc taaattttgt atatttacat
      361 ctatgattgt taataagtac attctcacag tttttattat ttcaacagaa aaatctacaa
      421 tattataatt tccttctttt ttatataatg actccttaaa tttgttaaaa caattatcta
      481 aattagaatt tatatcgtta aatggtggtc ttattatgtc acgtattatt aaaagatttt
      541 gtatatctac attatttgtg attgcctcat ccaaaataaa taaattatat gcatcattta
      601 atgggtcatg ggcatctcca ctaaactcta agttaacaaa ttcaagtaaa tttttcaatg
      661 atatatagtt catacatctc ataccacaat ttatatattt ttcttttata tctacaaata
      721 aatctctaat gttatttaca aaccttggat ggttattttt tttagcactt ctcatatctg
      781 tgttattgaa acatgtcaaa tccaaattac caaaagtata tattccttta atatcagaaa
      841 atatgccaag ccatttttta aactttctca tgacctcttc ataacttggt gcactcttca
      901 attcttcaga agatatatgt gttaattctt gtatatgagg atacaactcc tcattactta
      961 ctggtcttat taaagattta aatttatcaa tattttttgt tttttcatca tacacaactg
     1021 ctccaattgc aattatatca gaattaaata ctgctctttt tgatttagaa tttggcatat
     1081 tcatttcaaa atctatatat actcttttca atataaacac cctttccaat tgtttatagt
     1141 gattcttttt aactattttt attcaaaatt ttctaagaaa gaatgtttct ccccatcttt
     1201 ttgccaacca agtactgaat caagatttac attttctgcc gccttaaata tagatttttc
     1261 tacattttta aaatttgatt ctaaactctt tattaagtct tttatctcat atcttttatt
     1321 acctgttttt ttagcagcaa ccatacatgc acaatttaat ggccatatac cactattttg
     1381 aataaatctt ataatatgtt cttctcttat ataataaagt ggtcttataa tttttatacc
     1441 ttcaaaatta gtagaattaa gtttaggaag cattgtttta aaatttccag cacacaataa
     1501 gttaagcatt gttgtctcta ttacatcgtc ataatgatga cctaatgcaa gtttgttgca
     1561 ccctagttct tctgcctttg aatataatgc tcctctcctc attcttgcac acatatagca
     1621 tggataatct tttgctattt catctgctat ctcaaatatc cttgaatcaa ataaatgtat
     1681 tggtatattt agatactcac aattatctat aagtaattgt cttatatttg catgatatcc
     1741 agggtccata gcaataaatt caacatcaaa attaacttgt ccatgttttt ttaactcttg
     1801 aaacatttta gccataagaa tactgtcttt tccaccagaa atcgctacag ctatcttatc
     1861 accttcttca accaatttat aatctcttat tgccttcata aacttagacc ataaattttt
     1921 tctatatttt tttattatac ttttttctat atctcttact ggaagtcttt cctcaaaagg
     1981 aactataatt tcacagcctt ttcctgatag ttcactcatc taatcacctc gtatatttat
     2041 gttaataata ttttacaaaa aagtctacct tcatccacaa aatactataa tttttacttt
     2101 aattttacta aataatttat agtttacaat aacacataaa cttataataa cataaataac
     2161 ctctttcttt tattatcttt tttatttttc tcatttaata ttttattatt agtaacgatt
     2221 tttaaatgat tgaatattat acactagata gagttaccta tctatttaca acaaggaggt
     2281 tttcatcttg gaaaataaga ctagagatat caaaaaaaat tgtggtccat ctttggctag
     2341 accatacatt aataatcaaa ttttcacaga aatgtactgc ctttctgatg cattaaaatt
     2401 tggaactata tttccagaac taaacttact agagtctgaa atgtacaaca aagaattata
     2461 tgctaagcca aaaaaatata gaggaggtag aagataatga aagactcatc tagagctgaa
     2521 cttatgagaa aagttcagga aacatctttt gcatgtgttg atatgaactt atatttagac
     2581 aatcaccctg atgataaaaa tgctatcaac acttataatt cattatgtaa tcaatttgcg
     2641 caagctagat atgcttacga aaataaatac ggtcctttaa ctaactttgg gtatgctcca
     2701 agtagatgcc cttggcaatg ggctgaccaa ccttggcctt gggacagaga atttaattat
     2761 tagacatcaa gtattggagg attgaaaatt catgtggata tatcagaaaa ctatacaaca
     2821 cccagttaat ataaaaactt gtgaccctag aatggctaaa tttcttataa ctcaatttgg
     2881 tgggccaaat ggagaacttg ctgcatcttt aagatattta agccaaagat atacaatgcc
     2941 tactggtaat atgcgtgcac ttttaacaga tattggtaca gaagaactag ctcacgttga
     3001 gcttatatgt actatggttt atcagttaac ttctgatgca agcccagaag agttaaaagc
     3061 tgcaggtctt ggttcaaact atgctcaaaa tggatatgga atttatccaa cagattcaaa
     3121 tggtgttcca tttgatgtaa gacctatagc agttatgtca aatcccgtaa ccgatttaca
     3181 tgaggatatg gcagctgaac aaaaagcact tgcaacttat tatcaactta taaacctaac
     3241 agatgacgtt gatgttatag atgtattaaa attcttgggt caaagagaaa taattcacta
     3301 tcaaagattt ggtgaagctt taatggatgc ttacgagtta gaagaatctc aaaaaatgtt
     3361 ctaaaatttt tatttgtata actattatta tttgataatt tataatttac tgttgtgtta
     3421 aaatttataa aaaatataaa tataatttat tttctataaa cagagaaaat aaataaaaag
     3481 caggtatcaa tcaaatagta acatgtatta tactatacat tactatcaat attgtacctg
     3541 ctttcatatt ataagcaata aagaaaaatc tatttattag gttttataat aaaaacaatt
     3601 ataaaactct tcttgcattt acatatctac ttgaatagta gctactattt atattagata
     3661 ttgttacttt ttttgatgaa cctgaagatg catgtatcat atctccattt cctatgtata
     3721 ttccaacatg acttacagaa ccattatttg aaccttgtgt atcaaagaat actaaatctc
     3781 cacttctaag gtctcctcta tttacatatg ttccatactt actttggtct ctagatactc
     3841 ttggtatact aactcctaca gattttttca taacgtactg tgtgaatcca gaacagtcaa
     3901 aactatttgg accttctgct ccccatacat atggttttcc aagtagtgtc tttgcaaaac
     3961 ttattacact atcagctcct tgacttggag aattagtcga ataagatgga attgaagtat
     4021 caacagaacc tttttcagca aggtattgac ttgacacata tccagtttga ttgccataac
     4081 ttacttttgt ccatcctcca ctttcagaaa tacttccaac ctcagtacca taacttaatg
     4141 tagctatttt agaatgactt gtacctggtc ctgttctaac gttcaatgac tttgctgtta
     4201 caacctttgt accctttaca aggtcatttg aactgttttc agcattttca tttgtagagt
     4261 catttacact agttcctaaa tatttacttg aaacataacc tactctacca ttagaactta
     4321 tttttgacca tccatttgac tcagatatgt atccgacttc agtcccatat cctagtgttg
     4381 atattttaga actacttgta cttggtcctg ttctaaaatt taatcctttt gctgttacaa
     4441 cttttgtcga cttaactgaa gtatcactac tttcattgct acttccaagg ctatttattg
     4501 ctacataatt tccatgcaca taacctgtgt ttccattata tttaactttt acccaagaac
     4561 cttcttttcc tacgtactca actttatcac ctttgtaaag tttccccatt gattcatggt
     4621 ttgtacctgg tccttttcta aaatttaccg cattccctgt tattgttctg ctttctatac
     4681 tcacactctc tacttcagac tcattagcat atgctaaatt ccccatagta ggcattatta
     4741 tcgcagttgc cattatactg gctgctattc tcttttgatt aaaattcata actttccact
     4801 catctcctct tttctactat ctttatttca cttcaaaata taaaagaaat aattgacact
     4861 attaaaatat caattatttc ttttatatta atattattac aaatttgtaa ctatttgtct
     4921 atagtaatat ttgcttacca taaattacca tgtataaatt ttaatcttta atagcctgta
     4981 atttagtaat atagccatct tttacctttt ttaaaaatgg ctatattttt taactttttt
     5041 gtaacttttt aaaatccagt tgagccaaac ccaccttttc ctctttcgga gtcacttaat
     5101 tcttttactt cttctatgtt aatatcatag ataggtttta ctatcatttg agcaattttc
     5161 atatgctttt caaccttaaa atcattttta ccatgattta ttaatataat tttaagctct
     5221 cctctgtatc cttcgtcaat agttcctggt gtatttaata cagtaacaga atgctttaag
     5281 gcaagcccac ttctaggtct tacctgcgct tctgtcatag taggaagctc tatacatatc
     5341 ccagttttga taagtttagt ctctccagga ggtattacaa cctcttctat agaatacaaa
     5401 tccataccag catcaccttt gtgagcaaaa ttaggtatta tagcatcatc atttaatttt
     5461 tttactttta aattgtacat cttatatctc ctttcaactt tctataaata ttataactta
     5521 aatttcgacc tcttgaagtt ttttattttt ttgtggtaat ataattatta gtgttttaaa
     5581 ggaggatttt ttatgaaact tgtacttgct gagaaaccat ctgtggcaaa aactatagca
     5641 tcatttttag gtgcaaagac cagacaagat ggttactttg aaggaaatga ttatataatt
     5701 acttatgcag ttggacactt agtatcatta tatgatatga aggattatga taaagataaa
     5761 tactctggct cttggaaaat gaacaatttc ccatttgttc ctgaggataa gtttaaattt
     5821 aagattgata gttctaaaac taaacaattc aacactgtaa aaaagctttt gaatagaaaa
     5881 gatgtagaat atgtaataaa tgccactgac aatgaccgag aaggagaact tatagcattt
     5941 ttaatatttt tactggcaaa aaataaaaaa ccagtaaaaa gaatcttggt aaatgaatgg
     6001 acaccagaag atattacaag aggtataaaa aacctaaaag atgaagatga aatgagaaat
     6061 cttcaagctg ctggatatac taggcttatt actgactggt tgattggaat aaatttcact
     6121 tctgttgcta cattgaaata tggaaatggg aaactattaa acataggtag ggtaattctt
     6181 ccaacagtta aattagtcta tgatagagat atggaaatac taaactttgt tcctaaaacc
     6241 tattatgaaa tagaagggca ttttaaagct gaagctggtg aatataaagg taaatatgtt
     6301 aagggtaaag aaagtaaatt tgatacactt gaagatgcaa ataaaattat agcttcaatt
     6361 acatctgaaa ctggtaaaat actagataaa aaagttacta tgtcaaagga atatgcacca
     6421 aaacttttta gtttgacatc acttcaagga tatataactt ctaagtattc caattttaca
     6481 tctgataagg ttttaaatgt ctgtcaatct ctctatgagg gtaatggtaa gggtggatac
     6541 ataacttacc ctagaactga ttccattttc ttagaagaaa gtttggcttc aaaagcttct
     6601 caaactttag ataaattaaa ggttggtctt gaatatgaaa ataaaattaa attttctaaa
     6661 actaaaagag tttttgattc ttctaaagta gactcccata gtgctataat tccaacttat
     6721 ataattccaa aaagtttatc taaggatgaa caattagttt atgatgccat aaaagataga
     6781 tttgtagcaa actttatgcc tcctgctgaa tatgagaata cagaaattaa gactgaagta
     6841 gataattgta ctttcttaac aaaaggtaag gtgcttaaat caaaaggata ccttgaggta
     6901 tataataagg aagaaaaaaa cgatttactt ccacttgtaa ataaagatga tgttgtagat
     6961 gtgttagaaa taaaaccatt aactaagcaa actactccac ctaaaccata tactgaggac
     7021 acacttttaa aggctatgaa aaattgtggt aaaaatgtgc ctgaagaaga tacaacagtg
     7081 ctatctggat attcgattgg aacatcagcc acacgtgctg atgtgttaaa gaagataagt
     7141 caagtgggct atgtaaagaa aaaaggtaaa tcttattcta taacagacct tgggaaaaat
     7201 ttagttgaaa tttttcctgt taaagactta tttgatgtag attatactgg aaaacttgaa
     7261 aaaagtttaa gcgatattca aaaaggaaag tatacaagaa aagaatatct tactaatatc
     7321 attagtttta tatatcaaaa tgtcaatatt ataaaacaag atgcttcaaa aaatataaac
     7381 acagaagcat atactttcga ttcaaaaact aaaaaattta ctaaaacaaa agaaaaaaaa
     7441 cagaaaaaag atgtaactaa tactgaaaaa gaagttgcta tatcaaagga ttctaataac
     7501 aaaaaagaag ttaaaaatgg tgatgaaaat caatctcttg gcaaatgccc catttgtcaa
     7561 ggtgatgtac tagaatttga caaaggcttt gcttgtaaaa atcataaaga atgtaaattt
     7621 gttatttgga aaaatgataa gtatttaagt ctttataaaa agaaagttaa caaaacaatg
     7681 gtcaaaaata ttttaaaaaa aggtgaaact aaagtaaaat ctttaactgc taaaaacggt
     7741 aataaatttg atgctacatt aaaatatgat aaaaatccag atactggcta tttcaattgg
     7801 aaaatagagt ttgacaacta aatattcata agaaaagaaa tagcagtagt ataataatct
     7861 atattatatt actgctattt cttttcttat gaagttttaa cttttttaat agtgactttt
     7921 acaatcacac tctaacctaa tttctttact atttctgata actttaatgt atgttcatct
     7981 aataaagtta gttcctcttc agaaagatta gataattttt ttactagaga ttctttgaga
     8041 atagctttta ctgcatcaaa taatttaaat gctttatctg ttaattcaac cctaagaatc
     8101 cttctatctt ttgggtcagg aaatttattg actaaaccat gttccactaa tctgtcaata
     8161 atcggagtca tatttgattt taaaattcct aaattagaag ctatttgaga aattgatgat
     8221 gaatttgatg tcataagata aagaattacc ttagcatgtg atggagccat tggacattct
     8281 tcaaaataag ctttcattat atcagagtta ttttgaaact tttttaacaa atcgctttct
     8341 ttaaatatat tattttcaag cacaaataaa aaatctaaaa aagagtccgc tattttaagt
     8401 atattgttgt tatccatatt tgtaacatcc cttcaataga taatataata aaacattgtt
     8461 gtttaatata gtataaatta taaactatta ataaatttaa aacaagaaaa agttattgac
     8521 tcataataat tataaattta taatcaaatt agagaattat aaattgccaa taaagggaag
     8581 ttttttaatt agtctaaaac taaacttaaa ttataagaca ctttaaattc tacaacaagc
     8641 tagtgtgcaa tatataatag gaggagatat gaaaagatat ttaatagttt tcttaatgtg
     8701 tagttcactg tttttagttg gatgtggaaa aacagaagaa tctgaacctg agaaaccaat
     8761 agcagtttct gttcaaaaag caataggtgg agaaattgaa aacacaaatt ctttctcagg
     8821 aactacaaag gttaaagatg aaacagctgt tactgcacag actgttggca cagttcaaga
     8881 agtgtatgta aaacttgggc aaaatgtaag aaaaggagat gaattattga gtataagcag
     8941 tccagagcta gaaaatagtg taaagcaaag taaagcctca ctagatttag caaaagcaag
     9001 ttattcaagt gccactggtg gttcattaga ggcacaagta aatcaggcaa aaacagctct
     9061 tgacaatgca aagattcaat atgaggagtc tcaaagaaat tatgacaata ataagattct
     9121 ttatgaacag gaagtcatta gtttagacca atttaaaaaa atagaatttt ctttagagca
     9181 aacaaaacaa cagttagatt ctgctcaaag agcatacgat acagcaactt caaaaagtat
     9241 acctcaagct aaagcacttg ctaaaaaaca gcttgaccaa gctcaagtat catataattt
     9301 agcaatgagt aatttagaca aattaacatt aacatctcca gtagatggta caataacagc
     9361 taaaaacttt gattcaaagg aaatgataac acaatcacaa ccagctttta ttatttctaa
     9421 tcctagtata ctagaagttg atttaaatgt agcagaatca gatataggta aatttaagaa
     9481 agatggaaat gtagatgtta taattgaaga ccaaaggatt ttaggaaaaa tagattatgt
     9541 accttcagta gttgaccctc agacatcttt atatcctgtt aaagtacttg taaataatac
     9601 aaacaacaaa tttaaggcag gtatgtctgc tcaagtaaac ttaagtgttg aaaaagaaaa
     9661 tggtgctgtt acagtaccta aaaaagcaat atttgaagaa aatggtaaaa aatatgtata
     9721 catagcaaca aaagacaata tagcaaagaa acacttggtt caaactggaa ttgtaacaga
     9781 ggataaaata gaaattaaaa gtggtgtaag tgataaagat acagtgatta ttggagggat
     9841 aagtcttatt tctgacggaa ctaagatatt tcctgtagaa aaggagaagt agactatgaa
     9901 tttaacacag acttccgtta aacgtcctct cacaatcata atggtctttt tagtattaat
     9961 agtttttggt ggtattggat ataaaaaaat gtcaataaat ctaatgcctg atatagaaat
    10021 accagttgta atggtcatga ctacttggac aggtgctggt cctcaagacg ttgatgaaca
    10081 agttagtcaa aaagttgatg aaagtttatc tgccgtttca aatgtaaaat ctactatatc
    10141 aagttcacaa gaaagtgttt ctatggtagt tgctcagttt gaatttggaa ctaatttgga
    10201 tgaaataatg aatgatgtta ggtctaaagt tgatgcatta cagaccagcc tcccagatga
    10261 tgcagctaaa ccaacagttt taaagctgga tatgaatgca caggccatag gtcaacttgt
    10321 catatctgga ggaaatgaaa atagttcaca agccttaaga aaatacgctg aagatgtaat
    10381 tcagcctaaa atagaatcca tagatggtgt tacttcagca gaccttaaag gtggaaaaaa
    10441 agcacaggtt aatgtaatag ctgacccagc tgttctttca aattatgggg ttagtttatc
    10501 cactataaaa ggtgtcttat cctctagtaa taaaacattc ccttatggtt caattactca
    10561 aggtgaggat aaaatagttt taagagcgat tgataaatta gaatccctag atgatataaa
    10621 acagattcaa attcctgtaa aaggaggaaa tacagttaga ttagataatc tttgtagtgt
    10681 agattatgga tatgcagaca aagatagtat ttatagatac aatggaaaag acagtttggt
    10741 aatagatatt tctaaacaac aagatgccaa cactgtaaaa gttatgcaga gtgcatacaa
    10801 atacgtagat gaattgaata aggaaaatcc tcaatttaaa attaaaattg ctaatgatac
    10861 aagttcatac ataagtgaat caataaacag tgtaatgagc aacttgctta taagtgctgt
    10921 tatcgcattt attgtaatat ttgctttcct aaaaagtgta agagcttcac tagttgttgc
    10981 agttgcaata ccaatttcta taataggtgc tatagcaatt ctctacttta ctggtgaaag
    11041 tttaaatctt attactgcaa gttcattggt aatttcagtt ggtatggttg ttgataatgc
    11101 tacagttgta attgaaaata tatttaaata taggaaaagt ggcagattga gtcttgatga
    11161 ttgtgctatt gagggaacaa gaactgtaac aaatgcaata cttgcatcaa cattgaccac
    11221 aatagcaata ttcttaccta tcatgtttac agaaggtata gctaaaataa cttttggggc
    11281 attaggtaaa acactaatag cttcactagc attctccttt ataggtgcaa ttacactcgt
    11341 tcctagtgta tttgcaaaat taagcagagg aaaaaatagt caaaagatgc aagaaaaaga
    11401 tagtcctata tttgataagg taagtgaagc atataaaaaa ttattaagtg tatgtttgag
    11461 acatcaacgc ttagttgtaa tatcaagttt acttattttt gtagcttcct tatttggaat
    11521 gggatttata ggtatggact ttatgcctgc agcagacaag ggtgaattat ctatttctat
    11581 agaacttcca aaaggtctta gcctagaatc caatgattac tatgtatcta tgactgagaa
    11641 aaaagtctca gatattccag aaattaaaac tttaataaca actttgacat cagattcaaa
    11701 taatagtaaa gcaagtatag caattgaatt agaatctcaa aaaaatagaa aaagaactac
    11761 tgatgaaata gaaaaagaga taattgatag agtggctact gtaccagatt gtaaaataaa
    11821 tgtaagtcaa aacagtagtg ttatgggtgg agctggagga gcagacttca cattagaaat
    11881 gaaaggtcct gatttagatg tattaaaaat actgggaaaa gaagctgaaa aagaatttag
    11941 ctctataaaa ggatttagaa atgttgaaac ttctcttaca gatacaacac aagaagctca
    12001 atttactata gataaacata aggctcaaga atatggtgta aataccgctg aaattgcagg
    12061 catgttacgt acagcaataa atggtgactc cgtaaccact gctactattg atgattacaa
    12121 agtggatgta aacctaaaat ttaaagcaga tactattgat agcttagaag atataaagca
    12181 actaaaagta aactctgcaa ctggaaaaga agttcctctt ggtgcttttt cagatataaa
    12241 aatggcagat ggtctacaat ctatatctag gactgatgga gatttttctg taaatataac
    12301 tgctacactt gacaatttag atgctggtac tgctacaaaa ctagcactag aaaaaacgaa
    12361 taaaatggta attcctaaag attactctat aggtgttggt ggtgaaacag aaatgatgaa
    12421 tgaatctatg gcaagtcttg gattttcaat ggtcatagct atagcattag tttatatggt
    12481 aatggtagct cagtttgaat catttagtaa accatttata atcatgttct gtgttccatt
    12541 tgcattcgtt ggagttgtgc tttcgcttct agttagtggt caaagtttaa gtactgtcgg
    12601 tatgctaggt ataatcttac ttatcggtat tgttgttaat aatggtatag ttcttattga
    12661 ctacatagag caacttagaa aaacaaatcg taacaatgat ttaattggtt tggtttcaat
    12721 tggttgtgca gcaagattaa gaccagtctt aatgactaca gcaacaacaa ttttaggtat
    12781 gttgccaaca gcactatctc ttggtgaagg tggagaaact atgcaaccac tagccatagt
    12841 tataatgggt ggtctaactg tatctacact tataactttg gtgcttatac ctactatata
    12901 cttaatattt gataaatggg aaaataagtt ttcagacaaa atgcctaaaa tatttggtaa
    12961 gataacagat aaaataggaa gtataaaacg taaaataata aagaaaccaa aattgaaagc
    13021 taaagtttaa atagaatgga gggtgattgt attgaataaa aaaatgagca aaatagttgc
    13081 aattggctgt ggtgttggta taataactgc caatttaatc ccagtttacg cagataataa
    13141 tacttcttct ataaacaaag ttgataattc tattttaagt gactcaaata aaagaacatc
    13201 tgaaaaggaa attttgactg ctagagaagc tgttagtgct gcacttaaaa atagtgaaaa
    13261 attaaaaatg aaatcagaag aaataaaaat gttaaaagaa aagttagaag tacaagatga
    13321 gtttgatagt tttactggaa gtgacaactc gtttccatac gaccaaattg gacttcttaa
    13381 aaatcaaagt gaacaggcta aaggctttat ggaggaccaa atagcaaatg atattactaa
    13441 taaatttaac gatttagttt caagagaaaa tgagctagac aagataaaaa acaatcttga
    13501 aataaaaact aaagaaatta aagatatgaa attaaaaaaa gatttagggt tagtaacatc
    13561 tttagaaact gaatcagctg aacttgaact tcaaacacta caaaatactc aaaaagctaa
    13621 acttcaagaa ctaaaaaaca atcaagacta ctttaagttg ttgactaata tagatttaaa
    13681 taattatcaa ttggataaag aatatagatt tgaatctttt agagtaggtg gctcagttga
    13741 ttcatatatg gaaggtaagg ttaatgaata tttaaaatac gaccaattga ttttagaacg
    13801 tacagaagaa agctttaatg ataaagatga gaacaaagca gatttaccag atagacctaa
    13861 tcttacaaga ccagttgctc ctacaaaacc agagcaaggt aacctaactg atgatgaata
    13921 taaggttctt acggataagt atgaaaaaga ctacaagaga tatgaaaaag aagttgaagc
    13981 atacaatctt gaaagacaga cttatgctgc tggccttact acttatgcaa attatcttca
    14041 acaaaaattt aataccgaaa atggtctagt aacattagaa gacagtaaaa aagctcttaa
    14101 aaaagggtta attgatagct atgctcaatt acttgcttta gaagatacaa ttcagattac
    14161 taaaaaacaa cttgatttat cagaaaaaca attaaaaaat actaaattaa gatatgattt
    14221 aggattaatt actctaactg attataaaaa acaagtggta agtaatgaag atgctaaaaa
    14281 tagctatgac actcttattg tgaattataa ctcactaaaa aatggtatag aaaaaccttg
    14341 gatacttaat actggaaaat aattctggta aatagaaaga ttactttaac atacgtttga
    14401 ttaaaaaata gttatgcaca ctcgtggctt tagtcatgga agattcagaa ggcaaataat
    14461 agaaatagat tagtaaaaat atatttgctt ataaaactgt ataattttat agaggctatc
    14521 tcaaaataga gataagcctc ttttttattg tttaaattat aaaaatatat ttaattccat
    14581 acaaaaagag tgccttatga actaaaaagt tcattttgag acaccctcaa aagcttaact
    14641 ctaaatttaa ttatttttta tcaaatgtct catctatttt acatctcacc atgttaacaa
    14701 attcagaaat attatatcct ctaagtttgc atccacattt aggacaataa tccaatttcc
    14761 tagataccaa agccctacaa ctaggttctg gacatcttat ttttagactc tcatctgcta
    14821 ctttaaatcc acatcgtggg catatactac ctggacgtga tgatacttcc tttccacatt
    14881 taggacactt tgtcaacttt atcccctcca gtaaactcaa tttaattgat agttgaaatt
    14941 tctctctaca ataatatatg caatataatt aaatacgttt cacttacaac tatataagtt
    15001 aaatttttat aataaaaatc ccctatattc aatttacaaa tacttaattt gatacattga
    15061 acaatagggg attttatttt tatttagtta catattttgc agtctattat tatctaggat
    15121 tttttataga tgcttgagct gctgcaagtc tagcaattgg cactctaaat ggtgaacaag
    15181 atacatagtt aagtcctaca ctataacaga actctactga agatggttct cctccatgct
    15241 ctccacatat tcctagtttt aattctggtt taacttctct acctaattta gctcccatct
    15301 taactaactt accaacacca ttttggtcta gtacttggaa tgggtctttt tctaatattt
    15361 cttcatctac atattgacct aagaatttac cagcatcatc tcttgaatat ccaaatgcca
    15421 tttgagttaa gtcattagta ccaaaactga agaagtctgc ttcttgtgct atttcatcag
    15481 cagttaaaca agctctaggt atttctatca tagtacctac agtataagga acttctatac
    15541 cttcttcttt tattatagcg tcaacagttt ctactatcat ttttcttatt atttttaact
    15601 catttacttc tccaactaat ggaaccatta tctctggaga aactttaaca cctgctttga
    15661 ttgcttctat agcaccttgt attatagctt tagattgcat tacacatatt tcaggataag
    15721 ttattgcaag tctacaacct ctgtgtccaa gcattgggtt aaactcatct aaatcaacta
    15781 ttctcttctt aatatcactt acttttattc ccatagattt tgaaagttct tctatagtct
    15841 catcatcatg aggcaaaaat tcatgtagtg gtgggtctag taatcttata ttaactggtt
    15901 ttccatccat aactttaaat aactctacaa aatcttctct ttgcattggt aatatttttt
    15961 caagagcttt ttctctttgt tctactgtat tagataatat catttctcta actgctggca
    16021 atctagcttc atcaaagaac atatgctcag ttctacatag acctatacct tctgcaccaa
    16081 actctatagc tgcacgagca tctctaggat tatctgcatt agttctaacc atcatacatt
    16141 tgtgtttgtc tacccagttc attaattttt caaaatttcc agttaaagat acttctgttt
    16201 tcttaacatc tcctaggtat acatttcctg tagaaccatc tatagaaatg tattctcctt
    16261 cttttataac tacatcatca agtgctctta tttctttatt aaactcatca acttttattt
    16321 ctccacatcc agcaacacaa catttaccca tacctctagc aacaactgct gcatgtgatg
    16381 tcattccacc tctagctgta aggattcctt ctgctttaac cattccttct atatcttctg
    16441 gagatgtctc tagtctaact aaaactactt tttctccttt ttcatttgct tttactacat
    16501 catcagcatt gaaataaact ttaccacttg ctgcacctgg tgatgctggt aaaccttttg
    16561 ctataacctt agcttctttt aatgccttat cttcaaattt tggatgtaat aattggtcta
    16621 attgattagg ctcaattctc atgatagctt ctttttcatc aattattcca gcttcaacta
    16681 aatcaaccgc tacatttatt gctgctgctg ctgttctctt accatttcta gtttgtagta
    16741 tatataatct ttcattttct atagtaaact ctatatcttg catatcttta taatgacctt
    16801 caagtatatg agtaattttt acaaattcat cgaatacagc tggcattaca tctgcaagag
    16861 ttgatatatt ttgaggagtt cttatacctg caacaacgtc ttcaccttgt gcattcatta
    16921 aaaattcacc aaataattta ttttctcctg tagctggatt tctagtaaat gcaacacctg
    16981 taccactagt ttctcccata ttaccaaata ccattgattg aatatttact gctgttccta
    17041 agttatgagc tatatcattc aatttacggt atacgattgc acgaggatta ttccatgatc
    17101 taaatacagc ctctattgca agcattaatt gctcttttgg gtcttgtggg aaatcatttt
    17161 ttatttcttt tttataaatt gctttaaatt cttttactat ttcttttaaa tcatcagttg
    17221 taagttctgt atcaactgtg tatccctttg cttcttttac tctgtctaat acattttcaa
    17281 atttatattt tggaacttcc atagcaacat cagaaaacat ttgtatgaat cttctgtaac
    17341 tatcatatgc aaatctttca ttttgtgtag cctctgctaa gccaacaaca ctattgtcat
    17401 taagacctag gttaagaatt gtatccatca ttcctggcat agagaatact gcaccagaac
    17461 gaactgatac taataatgga ttcttattgc atcctaatgt tttatttaag tctttttcta
    17521 aagtagctaa atgctcttct atttctttta ttatctctgc tcttatactt tcattgttaa
    17581 cataataatc attacatgct tctgttgtta tagtgaatcc aggagggaca ggtaagccta
    17641 tcttagtcat ttctgctaaa ttggcacctt tacctcctag taaagatttc atgtctttgc
    17701 ttccttcacc aaaactataa acatacttag tttccattgt taaatccccc attaatcttt
    17761 ttattttaat ttatatcatt tttattaata gacattatta aatttctatt tctttgtata
    17821 tctttagacc attttctttc attatgtcta aaattatacc tgctgtttct tctattgcct
    17881 tatttgaaac gtttattact gggcatccaa ttcttttcat tatctcttct gaataatcta
    17941 actcctgaag tattctttct aaattagcat agtttgcttt actggacaat cctaaagctt
    18001 ttaatctttg ggttcttatc tcattcagct tttcaggtga attagtaaga cctattatct
    18061 ttttagtatc tatctcaaac acttctttag gaattggtat ttctggaact aatggaacat
    18121 tagctacttt tatattttta ttagctaaat acatactcaa aggagtttta gatgttcttg
    18181 atattcccac taaaattatg tctgcttgaa gaacacctct agggtctttt ccatcatcat
    18241 atttcactgc aaattctata gcttcaactc tcttaaagta agattcatct aattttctaa
    18301 ttataccagc ttctctttta ggttttcttc ctgttctctt gcttatttct cttagtatat
    18361 ctgtcattaa atctatacaa ctaagacctt ctctttcgca atatctttca acaatactgc
    18421 ataattcttc atcaactaat gtatatacaa ttaaagcgtt ttcagctttt gcattctcca
    18481 aagtttcaag tagtactcct ttattaatca tgtatggaaa tctttttatt tcataagttt
    18541 cattcacata aaactgagac atacatgcct ttgcaacttg ttgtgcagtc tcccctactg
    18601 aatctgatac tgcatatata attaggtttt tcaccagcat acctccttaa ttgtcaacta
    18661 tttctaagaa tagcttagtt atgttggttt ttgatattct cccaacaact ctcatatgat
    18721 ttttgtcttc tcccttatat tcaacaatcg gaatcgaatc tacttcatgt tctattattt
    18781 ttcttgaagc taataaaaca cttgctcctt tagttaaagt gactacattt ggagttcttg
    18841 tcattatcat acctattggc attttattta tatcagaacc tcctatagtt gcttttagca
    18901 agtcttttct ggaaacaact ccacataact cttcattctc atctataata actatactcc
    18961 ctacatcaga taaaaacata gtgactatta catcatatat actttcatcc ttcttagcta
    19021 gtacaggcat gctcattata tcctctactg ttttttcttt tacactttta ccaattaaat
    19081 ttatttcact aactcctgaa taaaaatatc caacttttgg tcttgcgtct aatattcctg
    19141 tcattgttaa tatagctaaa tcagatctaa gtgtagcacg agtcacattc aagctggagg
    19201 caatactttc actcgttatt ggttcatttt ccttaactat atctataatt tttagttgtc
    19261 tttcattaag ctgaataata atcaccttct ttcattgtgc tatacttttt atcttttcgc
    19321 atcttatata gtatattata taactatata taccattctg taaacagatt ttttattgaa
    19381 tacgatatat tttttactaa gttctctcgc ttaaagatat ttattatata ttaatggggg
    19441 atatttcttt aattaataga actatattag tattacagtt aatattataa tacataattg
    19501 gtcattttaa ttcattttat attaaaattt ttaataatat tatttcaatg tgaatataaa
    19561 attgcagaac taattcaaaa taatttttac gactacaaat aacctataat atacttttaa
    19621 agaaagtatc ctaacaagaa tatataaaaa tttaaaaggg ttgatttaaa aataaccatc
    19681 aacccttttt actaatatct atttatatta ccatcaaatc ttacccaaat attttttctt
    19741 gcaattgtct taaatgatat aaagtagtat ctttttctat ctctaccata tcgtaagtta
    19801 taacttcacc ttttttaata tcttttacaa ctttagtctt tttacttatc aaaccaatag
    19861 gtacagcatt catagccttt gctacatcgt atttttctat agtaccatag catgtatatg
    19921 ctccatagcc atccataaac tcaccttttt tcaaatcttt cttagctata gtcataactt
    19981 ctgctactag tccagcttta ggtactattg tagccttatg gtctaaaact gccatagctg
    20041 ctgataaagg agtctctaaa ctacataaat gatatggtct atataatatg taattaggtc
    20101 catcacccat acttaaatat tttagttcat cattaactgc ttttaattta tgggcaacta
    20161 ctacgaaaac tccaggtgct ataccattta caaaatcaac tacaccataa ttatctaata
    20221 ctccaccttc gctttttaat gcatatttct taggtacttc attaactgta gcttcaatac
    20281 catgaccacc tcttacatca ggcacaaatc cagttgcatt acacattaaa gccatttcta
    20341 ccattgtttt agttccttct ttaaaagaag ctatcatatg aggtgaagct ccttttcttt
    20401 ctgcttcttc tctaactgta tcaggattac aatctaaatc taatttatta tttttacctt
    20461 tacctatcac tctaacttca aaccccattg catctgcaaa atcaaataat tccattactg
    20521 cacctggctc atctcctgca gaacctgtaa atattactcc agcatcatct gctaattttt
    20581 taagtattgg tccaacaaca caatcagttt cagcatttaa cataactata tgttttttat
    20641 ttaaaataga gtttaatgct atctctgcac caattgcaat acccccagtt gcatctataa
    20701 ctacatctat tgacttagtt ttacaagcca caagaaagtc attacatgtc aatacttttc
    20761 cttcttgtaa ttttatttct gcatcctttt catttgttac attatctata atttcttcat
    20821 ctattcctgc atcagtaaaa gctttatgag ccaactccaa atctatatct acaacaatag
    20881 aagcttcaat acctttcata tttgccattt ggcttaccat tccatttccc atatgcccag
    20941 ctcctataag agctactttt atttttttac cttcctcttc caattttgca agttttctgt
    21001 ttaaatctaa cataccaatt cctcctgtta taataatttt attttcaaat taagaaatag
    21061 ttattaaatc tccaatagtt atatctggat ttcctatttc cacatgtatt tctcctggta
    21121 aatttacttc acattttcca tcaaatttga ttgtacaatg cccaatttct ctaagagtct
    21181 tctgagcaat atcaccaact gaaactatac aataatctct attccctata gtaagtgtat
    21241 ctcctatttc aacatcactt tttaatgttg ctattgaatg aattacagat atatccttta
    21301 agtcgtcatc attaatggtt tcatcatata taataagaca attgctttca tccattaact
    21361 ctttaactaa actgcctatc ccacttatct taacttcata tttcatgaca ttcctcctga
    21421 taatttatat ttatattgag ttaattaaaa gaaacattta ttttttcttt tataaatttt
    21481 atagcttgta caatactctc ttcatcttta aatttttgct ctgcactata tatatctaat
    21541 ccttctattt cttcaatctc tttaaattta gccattactg tacgcccttt taaaatttct
    21601 ccaaacttta taaacccatc tgaatctgaa gatataacgg ctatacttcc tttagaaaaa
    21661 tagcttttct ttttgcctgt agacactata tcaccctttt ttttagctct atttaaagtt
    21721 ttaaaataca atttattctg cttcattata aatatagtat ttaaaatata agcaacaaat
    21781 aaaattacta ataatttcat atttatacac cttccaaaaa tcacattatt tttaaatctg
    21841 tataacaact ataaatgctg tacaatagtt atataaggtt tttaagtaac acctttttaa
    21901 attctaaaaa agttctacat ttacttatct tattcgttaa ttttacatct tggcctatct
    21961 ttaaaacttc ttcataaatt tttactaata agtctgagtc tatcttattc tcacatggaa
    22021 acattgtcat aagaattatt tttatacttc tatttgcata ttctattggt tcttctaaaa
    22081 ttccaactgc cattaaaaac ttatctgatt tttcatttat agaatgagga aataataaac
    22141 ctttatcaaa tactgtggga gatttttctt ctctattgac tatatttttt ctaaacttct
    22201 catcaataca tcccaaatcc ataagatggt ccatcatttt ttctaatgag gcaagtatag
    22261 tcttttcatt taatatcata aatttatctt catctaacaa attatttatt agtaaatttg
    22321 tagaattagt agtgtcaata ttcccttctc ttaggcacaa tactgttttt aattgttctc
    22381 ttagtttgtt ttcatcaaat attgtattta tttttaatac tattgtattt atatttgatg
    22441 tgtctaaatc aatagttgta aaaactatat cgtattcatc taagttaata tttctcaaat
    22501 taaaacttga aagagtatca attttaggat tatttcctat cagtttttct actcttattt
    22561 tcaatagttt tgctgttcct agacctgtac tacatataat tgctattttt tttattgaat
    22621 agaatctact gctatttctt tctaaatatc cactgaaatg gattgctata tatccaatct
    22681 catcttctga aacttctaag ttatactttt tctctattac ttttcctgct atttgtgcta
    22741 atttaaatgg aagtatataa ttttgcttaa tctcttctaa caaaacattt tttaacttta
    22801 tattaaataa tagcctgttt aaagtaaaac taagatgata tcctagacct actcttaatt
    22861 catcctcatt tataaaaata cccatatcga catatatttg attaaatata ttttccatca
    22921 actcatcaat gtttttacta attctactac tatttaaagc acattctgat gctggtgcat
    22981 ttccactaac taacggtata gttaaataaa taatttcttc atcatttaaa gtacattcaa
    23041 acattcctga tattatatgt tttatttccc tagcaataaa gtattcatca tatgatttaa
    23101 gtaaatcaaa ctttacatca taatctttta ctttcttttc ttcttttact ctatagacta
    23161 aaactactat gtagttaata acttctctta acatttcatc tgtaacataa aaattatttt
    23221 ttttaaataa agtcaatagt ttttcttcta aatttatgat ttcttctttt ttgattcctt
    23281 taaaatactt tgaattactg aaatctttcc ttgagttttt atacaactga tttaatataa
    23341 acagtctaat atcaagttca tttccattta atttcatacc tgtattctgt tttttaatca
    23401 agtttaaatt atatgaagcc aaaacttttt ctacatactg gaaatcattt actaaagtag
    23461 ttcttcctac acacatctca tcagctaaac tatcaagtgt aataaatcca tctagttcta
    23521 tcaagtaatt tagtataaac tctactctat cttcttttga atttaatgaa aatacatttt
    23581 ttctattcat atcaataatc ttattgagta tctgctcatc ttttatttct agtttatagc
    23641 cttgaccctt tatatatttg attactgcta tatcattacc taaatcttta ttcaattgtt
    23701 ttatatacgt ccttacactt ctagttgtga cattcaattc atttgctatt gagttaatac
    23761 tcacaaactc ttttttacta cacataatca atatcttaaa tatcttgcgg tcaatagaag
    23821 gaattttctc agttacactc attttgtatc tcctccttga tttcattcta gtacaaattt
    23881 gaaaccaaat taatacataa aatttcactt taataaagga aaatttagta ttaatctaac
    23941 tcgataatta cagctaatta atagtataaa agctagtctt tcattaacaa aaaatcttga
    24001 ctagcttaaa tttatattta caattttatt aattaattcc aagccttata ttgacattaa
    24061 atattatctc aatgcaaata ctgcaactcc atatgcaata ataacagcta ttggaccagt
    24121 tattaaacga gagtaaaata aagctggaac accatactct acagtttctg gttctgcttc
    24181 tcccaaactt aatcctactg gtacaaaatc acatccagct tgcccattta ttgcaaataa
    24241 agctggaagt gctaaatatg ctggtattgc accaagacca atttgtgtac ctacaagagt
    24301 ccctactact tgagctataa ctgcaccagg tcctagtatt ggtgataaga atggaagtgt
    24361 gcaaattact gatataatca ataatccacc aatattacct gcaagtggag atataactct
    24421 tgcaatccag tctcccagtc cagatgctaa aataattccc ataagcatac ttacaaatgc
    24481 cataaatggt attacgttat tcattaccat ttggatagta tctcgacctg catcataaaa
    24541 ttttgatact acttgccctg ccccttgacc aatagaaagt attatgttct ttttagcata
    24601 ttcaccttgt gcttttgact taacctcatc ataattatca ggctttctaa tagaactctt
    24661 attttcgctt ttattttctt gagatttttg tggcatatct tccccatcta caacacttat
    24721 acagttagga ttaacatctg atacataata ttcttctgtt ataaattttg ctaaaggacc
    24781 tgtttttcca actggattta catttattgt aggtattttt ttctttggat aaactccaca
    24841 tctagcagtt ccaccacaat caataataac tactgctact tcttcatcag aaactccagt
    24901 tttaaatcca tctacaattt cacaacccag tagttctttt atttttaatg ttacttcatg
    24961 gataccgcca gcagtcattg atagtatctt atttctattc ccttcttttt ttatatacaa
    25021 aggacctccc cagcctgaag ttcccttttc tatttttaat attttattct cctccatttt
    25081 atctacctcc taagccttat ttgttgctct attttttctt gttagaaaag catacatttt
    25141 ttctgttact atacctctta taaaaattac aattagacca actataaaat accacaatgc
    25201 caatgtagta gtttctttac ctaaagtagt caaacctgca gatattccca accatacaaa
    25261 aagttctcct gcatttgcat gtggaaaaag acctgtaatt ggatgtacaa atgaaactgc
    25321 tgcatcataa aatcctgctt tgtgctcttc ttttaaaaat ctaccaaatg tatagcacat
    25381 aggatttccc aagaaaaata ctgatactaa tggaagtaga atatatcttg taaaagagtt
    25441 ctttcctagc ttagaagccc aattattaac tctttcctca ccaattatct taatcaaaga
    25501 gttaatagct accattaata caattagcgt tggaagagta cctgaaacaa gacctataaa
    25561 ttgttctccc cctttctgaa acaaaccgat aaaccactct gcacctttac ttagacctgt
    25621 aataacgttt tccataaaat tataacctcc ctataatatc tttaaatttt taattttact
    25681 gcttaccata aattttacaa attacatctt ttttctgtac tatatgctaa tattgtaaat
    25741 gtttttttat taatatcatt ttaatataat atttttgata aataaataca tcttttttca
    25801 attttataaa ggaaaaaatt gtactaatta gaattttcag aaatatacaa ttcttatttc
    25861 gactatattc taaattcttc ttagaaattt aagaacttat ttttatttct tttattatta
    25921 aaattatcta aatcttataa aaataaaaaa tagatgctct tttacgaaca tctatttctt
    25981 aatcaaatta tcttttagtt ttcttataga ttattttata ggtatataaa tatcaatttg
    26041 tgagttcaca ttactaggac ctaaaaatcg ttcatcatat acttcaaaat catctcttat
    26101 atcaagttct tcttttgaac ttaaaaacca agtaccccat atatattcat aagttttgtc
    26161 taaattatct aagctaccag tatgagtaaa tatagcatac tttccttcct taatagtttt
    26221 tgaaacaaat gaatttggaa tcacatcata actattaact tcaagtccta ttatctcatt
    26281 aaactccata ctttcactaa ctaggtgtat ttcagagatt gcttcacaga ttccaaaaac
    26341 tctccttgat ggcaaagtat ttgggacaat atgatgtact tttctgaatt tctcccacaa
    26401 gtcaggtaat gaattatttt ctaaaattac tttatccttt atacctatta cctttatttt
    26461 ttctatttct tttataactg gtttaatcgt tatatttcca acaagatgtc tcataaaatc
    26521 taactctaat tttttctttt taccaacaaa tacatcaatt ctattttttc tatattctat
    26581 agggctaacc ttgtatatag atttaaatgc tctgctaaat gcttctgaag attcaaatcc
    26641 actaccaata gctatatcta tcactttttt atcactatat aaaagttctt ttgtactact
    26701 tactaatcgt ctttttttta tataacttcc tacactttca ccaaacatag acttaaataa
    26761 gcgtgttaaa tgataataag aatatccagt ttcttttgcc acatcattta cagttatatt
    26821 ttcatgtaaa ttattctcaa tatacattac agctttttca aaatacttta agtaatccaa
    26881 tatggcacct ctcttctact taaactcttt aaatatgtaa aatagcacta ttttttacta
    26941 tactaaaata ttataactaa ttcaatacga taaataaaaa cttttagttg atttatatgt
    27001 cctaattatt tagaataatt aaatacattt tttattcaat gaaatcaaaa aagtcagatg
    27061 gtgctttttc aatatttatg tttatcctct gtgttataga tttaatgtca ttttttaaat
    27121 agtagctctc ccatttattc tctagtccac cccataaaat attaaacttt cctatattta
    27181 aatccataac tatacttttt aaagttccaa aaaaatcatt atagtaatta caagataagc
    27241 catttggata ttttgaagac aataaattca ttaactcttt ctctccaatt tttttagact
    27301 tatttatata ttctttaatt aatttatatc tatgaataga atttttcatt gattgtggat
    27361 ctaatttatg aagtttatca atatgtgtat gattagtaga gtgtaaaaaa tattctcttt
    27421 tactttctaa actgttgatt atatttactt cttttttccc atctaaagtc tccacaagtg
    27481 caatgtttcc agacttatct gcaagcaata aattaatatt gtatgcaatt ggcatatctt
    27541 ttaaatattc taatgcttca tctacatctt tgcaattttc taacaaatat ctaataacag
    27601 cccaaaactg taaacctaca attgctggtt ttcttaaacc atctgaattg cctacaggaa
    27661 taccacatga tgactgactt acacctaagc cacattcatt cataccttca cctcttccaa
    27721 attgcataat ggtagtacct atatgtgcat attttccatt taccttagtt ttacataaaa
    27781 caaaatcctc catattgtgt gagaaatcga aattacgtgc aaatagtaca tgcccatttt
    27841 cagttaattc tggtgctaat gcaacttgac tacaacctgg tttaagataa gtcatagtat
    27901 aatataaaat ttgattacaa ttcacttgaa ttgcatcagc aaaaccttgc aattcttcat
    27961 taagacctgg acaatattta tcaaacaact ctatcatctc tttttcttct tttttgctta
    28021 ccagattaga tttattaatc tgaccttcta ttatctctgg catattagca accaattctc
    28081 ctagtctgta tcctatctca taatttgtac cactcaattc aatatttctt acttctaaag
    28141 tttccatatg tacccctcct atatatctta taatcgattt tatcattcga attgtaatca
    28201 ttcatgatat tttgtgctac aagttaaaaa aggtcatata aaaacagata agcctctttt
    28261 tcatgtttaa aataataaaa atatatttaa tttcatacaa aaaagagtgt ctcataaact
    28321 aaaaagttca ttttgagaca ctcttcttat tttaaagagt ataattaaaa atagtctaag
    28381 ttctactctt ccttcatttt tttcaataat tctggatttt caaataaatt aaatcctgtt
    28441 aaagctaata tttttatacc atcaattact ctatcttttg catatgaatt tatagaagcc
    28501 tccaaaaatt cttttgtatg tagttcttct ccattttcag aaaacttcat caaaggatgt
    28561 atacatggca ttatttgact taaatttccc atatctgttg aacctaacat tacttgttca
    28621 tcttcatata ttccaaattc ctccataatc tttgtaaata tgtctaccaa aactttattt
    28681 tcatttaatc cttggcaagt tggttcaaag tgataaaatt caagttcaca tccagtggct
    28741 attgcagcac ctctagcaca atttttcact ttttctacta cttcatcaaa gtaattttgt
    28801 tcttttgccc ttatctctaa tcttactttt cccatatcag gtattacatt tgcagcagtt
    28861 cctgcttcta atataatacc atgtattctc gttccatcta ctaattgttg tcttagtgca
    28921 tttatattat tatatagtag tactactgca tctaaagcat ttattccgtt atatggctta
    28981 gctcctgcat gagatgcttt tccagtaaat atgaaatcta gacctcctat tgctataatt
    29041 tcaggtgtta cacaagtttt tgaatttgga tgtatcatca ttgctgcatc atagccatca
    29101 aatacaccat gttctatcaa gtaaggcttt ccatctccag tttcttcagc aggtgttcca
    29161 attatactta cttctccctt gtaagtatcc agtatacttg aaagagctat tccagctcca
    29221 actcccatag atgcaattaa atgatgtcca catgcatgtc cattgcctgg aagagcatca
    29281 tattctgcta taaatgctat tttaggacca tctccatttt tcttggttgc tttaaaagct
    29341 gtagccatac ctgccaagtt ttcctcaaca tcaaaaccct cttctcttag aaattctgat
    29401 atttttttag cagatttata ttcttgcaaa gcaatttctg gttcatcata taaagattga
    29461 catagcccta gaattttttc tttctttgaa tcagccactt gtattattct ttctttcata
    29521 ccaatcttac ctcccactaa atttatttag taatttttat attttattat aactttaatt
    29581 taactcatgc ttatcctctt ttaagtatct attttcccaa aactcagcat ttcttatatc
    29641 taactctata gggttaaaag ttctatcact cctttttatt cccatcttct tctgtcttat
    29701 ataatcataa tatgccttta tagctggttt ttttagtgta aagatggcaa ttaaatttat
    29761 atatgttaat acacctatac atatatcacc taatgcccag cttgtaagtg gttctataaa
    29821 acaacacatt gctgcacatg ctataagcat aaatctacag acattaatta tgtacttttc
    29881 atgtttttct gctttaattc tagttactaa gtaagataca ttagtctcca tcatatatga
    29941 gaaggctaat aaagttgtaa atgtaaataa taataaaact attgctataa aaatatcacc
    30001 taattgtgga tgtaatgtat ttattgcact ctgtacatat tgtggtcccg gttctacacc
    30061 tggtagtgct gtgcaaacac ctgtaacatt atacattcct gttattacaa tcataatacc
    30121 tgtagccata catattaata atgtgtctac ataaacagaa aatgcttgaa ctaatccttg
    30181 tttggctgga tgacttactt ctgctgctgc cgcaccataa gtcccagaac cttctcctgc
    30241 ttcatttgag tatatacctc tttttactcc ccaagatatt gctgaaccta gcattcctcc
    30301 aaaaactgaa ccaaatccaa atgcagattt aaacattgtt acaatagcct ctggaactaa
    30361 actaatattt gttataatta ttactaatgt cataataagg tatgctccac ccattatagg
    30421 tactactttt tcagcaaata aaccaatcct tttaattcct ccaaaaatta ttatcgctaa
    30481 tgcaatagaa gatgctactg ctattgtcat ttttgaaaat ccaaatgctt gattcattgc
    30541 tagatataaa gtgtttgatt gtgtaccagg cataaaaaat gtataactta ttattgcaac
    30601 tattgaaaat aaaactgaac actttttcca cccaagacct ttttcaaaat aatatggagg
    30661 tcctcctcta tactgcccat catgctcatc tttatatatt tgagctaaag tagattctac
    30721 aaatgcagtt gctgaaccta atgtagccat tatacacatc catactaatg ctcctggacc
    30781 tcccattgct attgctacag ctacaccagc tatatttcca gtccctattc ttccagccat
    30841 agatgtagca aaaccttgaa atgatgatat accaacatga gaactatctc cctcaagcaa
    30901 gagagtaaac atttctttta catctcttat ttgaaaaaat tttaatttca atgaaaaata
    30961 taatcctata cacaaacaca ttgcaactaa tacgggtgac caaacaattc cattaatggt
    31021 gttaactaaa tcggtcactt aactcaccac cattcatttt atatttatag acaataattt
    31081 aaacagctat atttcaatat tttatataat ctttatatta atatatctaa aaaatctacc
    31141 ttctatttat ttatattatc tttaatctac aatctacaaa tatttatttc taaaatcaag
    31201 agtattaatc atatctaaac ataaatttat aaaattttta acgacgtgtg tttgaataat
    31261 aatcaaacaa tataaattgg aatacatata atgaaaagcc tgaaattatt attatataaa
    31321 tagtacaata tatatttatt aatatataat taaatagtat ctagttagat tttaaatttt
    31381 cgtatttatt atgaggttta aaattgagta caactaccat ctattttgaa aatctcttag
    31441 aatttaaatt aaataggttt atgtaggtaa gaaaatagat aataattgcc actcaatttt
    31501 acaccttcag gggtaacttt atgttaaaac ctagaaaact tgataacatt ttgattttta
    31561 tactttattc tctaaacatt attataaaac ttaatctatt gatatttttt atgttattta
    31621 tacaatcaca ttcatcaaaa taagtattgt atttatatat acttaattac caaattgaat
    31681 atttaagctt ctaatttact tgctcttctc tttttaacct ttaatatata taaacaagat
    31741 agtattccaa taactagaat tgctatttgg aatataaatg tatatgtgta acctttattg
    31801 ccataagtat ctatccagtg tcctattaat gcaaattgga atacatctgg tgaaaatcct
    31861 aaagctgcag ctatacctat agtagttgct gaatatttaa ctggaacttt tacttcatct
    31921 tgtactgcat aatatatacc ttttcccatg taacctaata tacctactac aaatgttaaa
    31981 gctatgaata tagtcattgg agttgatgca ggtaatacta ggaataaaac tattactgct
    32041 ataccaaata catatattgg taaaagtact tttgtaggag attttaattt gtctgcacaa
    32101 tatcctccaa atggtgctcc aaataatttt agaccatgct gtcttattat tgctaatgca
    32161 ccagataatg ctacagaacc tccaagtaca gatgttatat atggtgtaaa ataagacatt
    32221 gtaactgtga atgaatatac acagaatata cttattccta ctagccaagt atttggtgat
    32281 tttagtactg ttataaaatc accagcagac attttttcac ctgcttcttc tctttcttct
    32341 ttaatatcta catctttaat tacaaaccat aatactggac acattgctat tgataatatt
    32401 cctaaagata tcattaccca tctcataccc aatgtaggag ttgcaaagca tgtataaata
    32461 tataagaata ttgctcccat tactactcca gaaactccaa ccatagcttc attaaatcca
    32521 taaaccttac cttgattatc ttttcctata actctaagta tttttaccat agaaggatag
    32581 ttcataacta atgatgtgat tgcacaacct acccaagtag caactgcaaa tggatagttc
    32641 atattaaatg caaataaaaa tgatactact ccattaagaa atacagaacc taaaattatc
    32701 tttctataat caaatctatc tgctaaccag cctcctatag gagctccaaa tatattacct
    32761 aacccataaa ttgtaagtag aaaacctagt tgagtgtttg tacattctaa tgcttttagg
    32821 attggatcat ataatgtata ttggataaat ggtataatat aaactaattc ccaagatatt
    32881 gctataataa caagttgaaa cattaacttt ccaaacttta taccgttttc tttttctccc
    32941 atatttaaac cctcactttt tatatttatt cacaagcata attgagttct ttttttataa
    33001 cttctgcaag tatctcaaca cctttaacga tttgttcttc tgacattgtt gtatagttaa
    33061 gtctcatagt attttttgga ccattatttg caaagaagga ctctccagaa acataagcaa
    33121 ctccagcatc aatggcttta tctaataaat catctacatt tatactttca ggaagttcaa
    33181 cccatataaa cattcctcca tctggttctg tatatttagc ttcctctggg aaatgtttct
    33241 tcatagcatc taacattagc agacatcttt tcttatactc tgctcttatt ttttctatat
    33301 gttcatttaa gttgtatttc tttaaaaatt ctattacttg tacttgcgaa aattgatttg
    33361 actgtaaatc tataccttgt tttaaaagtt ctgccttatc tatgatgtct acattaccac
    33421 acatccaagc aactctaaat cctggacata atacctttga aaatgaccca aggtacaata
    33481 ctttatcttt agtatcaaga gatttaagtg taggtagagg ttctggtgta aatcttattt
    33541 ctccataagg attatcctct attactatga catcatattt attcacgact tccataaaat
    33601 cttttcttct ttgtaaagac catgtttttc ctgtagggtt ttgaaatgtt ggtattacat
    33661 atatcacctt tatgttagaa ttttcagata ataatttgtc taaatcatct gttaccattc
    33721 cttcttcatc tgtatctact cctaaaaaat cacattcata aggtctaaat gcatttattg
    33781 cacctaagta acttggattt tctgtaacta ctacatctcc cttttctaat aaaatcatag
    33841 cacttaatgc tatcccttgt tgtgacccag tagttattat aatattttct gcttttgtat
    33901 caatattttc ttcttctttc attcttttta ctaatagatc taacaactca tcttcacctt
    33961 tagtaggtcc atatgctagg gcaaattttc ccctttcatt aagtactttt tgagttattt
    34021 cacttatctc ttctattgga aataaatttg ggtcaggaag ccctgcagca aaagatataa
    34081 cagttccacc acttgctacc ttctgagcta ttttcttttg agaatctctt atagctgaag
    34141 cttttaccat atccattctt tttgcatatt tcataatact ttttcctcct taataataat
    34201 ttcttattgt gatgctaggc acgctaatgc tattgaattt atttttattt cagctgtgtc
    34261 agaacgtgaa cctaaaatta tcggatttgt tgctcctaaa actatacctg cccacttagc
    34321 tttattaaat ctaagccatg actttcctaa tatattccct gcttctatat ttggaaatac
    34381 taataaatca acatcaccag caatattact tttaatacct ttatgttctg ctgcatgtgc
    34441 atcaaatgct acatcaaatg ctattggacc ttccactata cactttggta tttctcccga
    34501 tttttccatc tctacaagta ggttggcatc cactgtagat tgtatcttag ggtctaccat
    34561 ttcatttgca gtaagtatcg cagttttagg attttccatg cctatacttt tcatagtaag
    34621 aagtgcattt gtcattatat cttttttttg atttaagttt ggcgatacat ttattccact
    34681 atcagtacaa taaagaagtt tatgatattg aggtaattca tatactgcaa gcaaacttaa
    34741 taatcttcct gttctaagac ccgtttcttt atttaatata gctctcatat agacacttgt
    34801 atttactaat cccttcataa gaactttagc ttccttattt ttaactatct ctacagcttt
    34861 tttaactgat tcatcgggat tttgacaacc tattatttca tgacctttta atccaatttc
    34921 tcttgatata ctttctattt tatccttgtc tcctacaaga attggcttta taatgtttaa
    34981 atctgttgct gatttcacag cctttaatac ttctttgtct tctgcaacag caacacttac
    35041 aataacaggt tcaagctttt tagcctcttc taataaatta ttaaaatctt ttaacatact
    35101 ctttctccta aatattaata agtttttgct atttcttctc cattaagtac tctaagtgcc
    35161 cctagagcaa gtgcctccat ttccatctct cctggtacta tctctattgg agctagatat
    35221 gaaacttttt ctgctactcc tttgactacc atttctgagt gagatatccc tcctgtcaag
    35281 ataactctat ctacattccc tgaaagtgaa gctccataca tagaaatttc ttttgctact
    35341 tgataaataa atgcatccat tataagtttt gccttttcat caccctcctt gattctgttt
    35401 tcaatttcta tcatgtcctt tgttcctaaa taatcgtaca ttcccccaat cgaacttact
    35461 tttgcgacca tttcatcatg agtatatttt ccggagtaac acaattctat aagaggatat
    35521 gcaagtaatc caccactcct ttctggagaa aatggaccat cagacctacc accacttcca
    35581 tcaatcattt tgccttgttt atgtgctaca atcgatattc ctgaacctaa atgagctaca
    35641 ataaagttat aatcctcgta ttttccccct agtttttgtg caatttttct tgaaacagct
    35701 ttatggttta atgcatgtaa ccaacttgct ttttctatgt ctgatattcc tgtaatcctc
    35761 gatacatcat caaattcatc tacagaaact gggtctacta caaatgattg tactcctatt
    35821 tcatcagcta tagttttagc taataatgca cctaaatttg atgcatgttc cccatttatt
    35881 tcatttctca tatcctcaat catttcttca ctcacagtat aggtaccacc ttttatagcc
    35941 ttcataagtc caccacgacc aactactgcg tcaaaagaat ttatactatg attctcacta
    36001 cttaaaatat ctactatcag ttgttttcta taatcatatt catcaaatac tttagaaaaa
    36061 ttttttaaat cttctcttgt atgggttata ttttttttca aaatttcatt ttcatcttgg
    36121 aaaacagaaa tttttgtgga tgtaccacca ggatttatta ctaaaacttt caatttaaca
    36181 ccccctagtt ctattataca gaacgccgtt cttgtattcc gacctaaaga cttcgtccca
    36241 ttgtccagaa cgacgttcta tattttatta attaaatact aacatataaa aataagtatt
    36301 tcaataatta ttttaaatat ttaaaatatt cattcgtagt cgtatccagc ttcaaatgct
    36361 tctacatttt tagaattgaa tttacctttg ccttgatttt caaagtattc acacatacca
    36421 ctttcaaatt cttcttttgt aaataaatcc aaactcttta ccatagcacc taacatgcaa
    36481 atgttagcag ctttttcatt gcctaaattt tgtgctattt cagtaacagg tacttttata
    36541 acattaatgt cttctctgta ctttctatcc ttacttacta gtgattcatt gacaaacata
    36601 taaccatttt ttttcattaa actttcatac ttatctactg atacgctgtt cattcccaat
    36661 agtatatctg gattttttac acaaggattt gcaatttttt catcacttac aacaacattg
    36721 caatttgcac ttcctcccct catctcattt ccataagatg ggaaccatgt aattttcttt
    36781 tctgccttat atgcaacata cattataatt tttcctgctg taagaactcc ctgtcctcca
    36841 aaaccagcac atataatttc attcaacata ttatttcctc cctaatcaat aaattctcca
    36901 agtggatact ttggaacaag ttcattttca attctcttca tagcatctac tggctttaat
    36961 ccccagtttg ttggacatgg tacaagcact tctattaagc aaaaaccttt cttttctttt
    37021 tgtttttcta gagctttttt gatgtatctt tttgttgtat ttatttcttt agggttagtt
    37081 attgttcctc ttgctagata tgctatatct aaatttccca taacttttac aacatcaaat
    37141 gttgaaccat gatctgcgta atttctaccc gctggagtag aagctgtata ttgaccttct
    37201 atagtagttg gagccatttg ccctcctgtc attgcaaaca tattattgtt cataacaaga
    37261 aatattacat tatcatttct agtagcagct gacatagttt ctccaagccc tattgcataa
    37321 gctccaccat ctccagctat tgtaaatata tatttatctg gtctaactct tttcatagct
    37381 gccattgctg ctcccatttt accatgaggt ggaacgacaa catctacatt catactaaat
    37441 tgaaacatat gattacaacc tatatctgaa catataattg tatcttgaca tatatccatt
    37501 tctgttaata cttctccaat aattctatcg actatagagt gtccacagcc tccacagaac
    37561 atattttcac acatcattat tgctggtgct tttttagcca taattaaaat acctcctctt
    37621 gcttagcttt tccatctata atctgttgag caaaatctat taattgattt acttctgcca
    37681 tatattgagc tgttgctact gaatatactg gaaatctatt atcacatgct ataattacat
    37741 cttccttcat ctgtgccatc atgttcattt caactgttac aagtcccttc aatgaatcac
    37801 ttaatttctt aaatgctttt cttgggtaag gccacaatgt ttttggtctt attagaccta
    37861 atttcattcc ttttgctcta gcatctctaa ctgcaccttc tgctattctt gatgaaatac
    37921 cgtatgccac aaataccact tcagcatctt ctatttctat ctcttcccat ctttgttcat
    37981 cttcttgaac ttttctcatt ttttctatat accctttttg ccatgtatct tggtcttcaa
    38041 aatatgttat atcagttatt actttatttt tttctcctac aggtgttcct tttgcagccc
    38101 atggagcttt atccatatcg tattctttca ttggtggtgc tatacaaggt tctaccattt
    38161 gacctattgt agcatcagaa agtataagta ctggatgcat atatttttca gccaattcaa
    38221 aagattcata tgccatatcc atattttctt gaacactatt aggtgctaac acgattaaat
    38281 gataatctcc atttccaccg ccttttactg cttgccaata attatcttga ccagctccta
    38341 taaatccatc acctatacca tatctttgca cacatgctac aactgctggc aaaccagctg
    38401 atacccaata tgcaatacct tcttgtttta atgaaaatcc tggaccagat gaagaagtca
    38461 tagctcttgc tccaagtgca cttgctccca taaccatatt tacactggct atttctgatt
    38521 caccttggat aaatactcct ccaacttctt tttgtctcca tgccatcatt tctaatattt
    38581 ctgattgtgg cgttattgga taacctgcat aaaatctgca gccaccacgt atagcacctt
    38641 ctgctaaagc ttcatttcct ttaattaata aactttgcat accttttctc ccctctaata
    38701 aaaataattt ataatatctc aaatactaaa tcagggcaca ttgtataaca agcgccacat
    38761 tgaatacatt tttcttcatc gactttaata gttacaaagc cttttttatt tgtgtagtca
    38821 gaaagactta ttgcatcttt tttacaagct tcaatacaaa gatagcatcc cttacatctt
    38881 tcaacactca acttgacttt ttccatttct caaatctccc ctttatgtaa tatttttact
    38941 taattttaaa tatataatat ttatattttg tataaatact atatatgcat caattttgtt
    39001 ctatagtata gaaccttgtt ctatttttat tgcttaatta aaagataaca cattcgctta
    39061 tatatttcaa taacatttta aattttaaga atatttaatt ttagattaaa gaaaaatagg
    39121 ctacatttaa actgatattt acaaataaca atttaaatat agcctatttt tattatcgag
    39181 attaaaaatc atctaaaaag ttcagatata ctttttgcag tttctataac tcttttaatc
    39241 ttatactcaa agtccccttc tctcattctt atagttggac ctgacaaact tatggctgca
    39301 atagctttat tatttttatc taagataggt gctccaatac aagttagtcc atgttctagt
    39361 tcttcatcat ctatagcata tccttgttct tttatttttg ctaaaaaaag catcatatca
    39421 tcccaattat caattgtatg ttctgtatac ttgtgtattg gtgtttttct atatttttca
    39481 aaatctatag aatcattaaa tgccataaga catttaccaa ctgctgaaca ataacattca
    39541 ctacttgaac caacggatgg atttactgaa agtaattgat ttgaaccata ctctttatgt
    39601 attatgatac ttcttggaga atcttgagct ctttcttcta atatagatac attaactact
    39661 tcgttaaatt cttgatttaa ttttttcgta tatggtttta ctatttcagt caatgacatt
    39721 ttttctccca caaccatacc tattgcatat aaatttattc ctagccaata cttaccattc
    39781 tctgcatttt gtataacaaa acctttgttt tcaagagtaa ccaaagttct atgtacagta
    39841 cttttatata ctcccatagc cttgcttatt tcagttattc ccatttctct cttttcatga
    39901 tataacagca aaattatgtc tagggctcta tctaatgcat ttattatttc tcccatatac
    39961 aaaaactcct ccttcaaata ttaagtgcta ctcccacact ctactaaata ttatatatta
    40021 aaattacaaa attatctatt tatcttaatt atattttata aaacaaaaat attatactta
    40081 atttgtaaaa taaaaacaaa atactcacta tgtccttatt attcttactt ttaatagaat
    40141 tattctgtta tatttttatc ctgactagat aataatatat atatctatta tacaatagat
    40201 atatttttat acaagactaa caatgaggtg aaataatgga taattttaaa aagatattgt
    40261 taaatgaact acctaatttt aaagaatatt cttcaaaatt tttaaatgga gaaataaata
    40321 aaatgcaata taagggattt tctggtggat atggtgttta tgctcaaaga gacaaaaaat
    40381 cttttatgat aagacttaga gtatctgctg gagttttatc tcagtatcaa cttaataaaa
    40441 tctatgaaat agctattaaa cacaacttag ataagataca cttaacaact agacaagcta
    40501 tacaattaca cgatttatct ataaattcaa ttgttgatat catggaagaa ggaataaaaa
    40561 atgatatatt cactagaggt ggtggtggta attatcctag aaatgtcgga ttatctccat
    40621 tatctggagt tgaccctagt gaagtctttg atgttactcc atatgcagtt gctactgata
    40681 aatattttat caaaaatgct actacatacc atttacctag aaaattaaaa gtttcttatt
    40741 ctaattgtta cacagatact gctcattgta gtatacaaga cttaggattt gttgctactt
    40801 tgaaaaatga tgaaccatat ttcagagttt tcttaggtgg aggtctaggt aaacaaccca
    40861 aagttgcttt agaacttgat gaacttataa aaccgaaaga tgccttatat tgtgttgaag
    40921 gtatgattaa attctttatg gattatggaa attatgaaaa taaaaacaga gctagggtta
    40981 gatatatggt cgaatcactt ggtgaaaaat tattcttaga aaaatttaaa gaatactata
    41041 aattagaaaa agaaaatggt agtcttgaac tcaatattga agaaatagat tactctaaac
    41101 ctggggttaa aatagatata caggattcta gactaatacc tcaaaaacag gatggtttat
    41161 acactgtata tatacatcca gttggaggta ttttgttaac aaaggattta agtactttac
    41221 ttaaagaatt agataatatt gaaaatccta tgattagact aggaatgaca gagggattat
    41281 atattttaaa tttaaatgga aatgaagcaa aaagaatatt agaaataagt aaaactatta
    41341 gttgtaattc tcaattagaa caaagtatat cttgcatagg tgttccaatt tgtcaaatgg
    41401 gcatacaaaa tagtcagaaa atgttacatg aaatcataga ttattttaga ttacaaaata
    41461 ataaagaaat tttaaataaa gcacctaagt tatatatatc aggatgttta aattcatgtg
    41521 gtgttcatca agttggtagc ataggtttat gtggtaaaaa gaagaatgtt gatggtatat
    41581 ctacagatgc atttgaatta tttgttggag gcagttttga aataggtaag actagattgg
    41641 gaaaatcact tggagatttt aaagctagtg atattcctga aatgctttat aaaatatcgg
    41701 acgcatcatc aggcaatttt tatgaatggg taaattcaaa tgataatatt ttaaacaaaa
    41761 taactgataa gtataaaata taatttatta tatttactta caaaaagcat gggtgtctca
    41821 aaatgaactt tttagtttat gagacactct ttttctatga aatcaaatat attttcatca
    41881 tctcaacaat gaaaaataag actatctcta ttttgagaca gccttatttc ttataaatag
    41941 tttaaatttt atttataaac aattttagat aaatcacaaa ttcctagcat agtatcatat
    42001 acttgtttaa gtaaagcaag tctattgttc ttaatagctt catcattatc cataaccata
    42061 actgtatcaa ataaattatc aactactggt cttaaagatg caaattcatc taaagcaata
    42121 ccatatttct tatcctttaa taattcatta acttttacct ttacttgttt aaattcattg
    42181 taaagtttaa tttcagcatc ttcttttaat aaagattcat caattttatc actttctgct
    42241 ttttgagcta gagtagaaac tctattaaat gcagtaagca tctccactaa ttcatctttt
    42301 tctagccaat tattaagctc taaagctctc atatgcatat cagaaacatc atttatatca
    42361 gaacttaaaa cagcatcaac aacatcatat cttattccta aatctttaaa tagatttttt
    42421 actctctcat tgaagaaatt cattatttgc tcaacaactt cttctttatt aaaatctaat
    42481 tcagaataat tgtctaaagc atgttcaata agtactttta tatccacagc aacttttctg
    42541 tccataagta tactaagtat acctaaagct tgtcttctta aagcatatgg gtcttgagaa
    42601 cctgttggtt gtattcctat agcaaagaaa cctgctattg aatccaactt atcagctatt
    42661 gataaggcaa ctcctgcatt agtcttagga agtatatctc ctgcaaatct tggaagataa
    42721 tgttcaaaaa tagcttcact tacaacatca ttttctcctc caacttttgc gtattctttt
    42781 cccataaaac cttgtaattc atcaaattct cctaccattc cagtaactaa atctgcctta
    42841 gataatttag cagcccttat agtatctgcc ttttcatcta ctaaacctaa actatcaagt
    42901 atatcagcac ttaatttttc aagtcttaaa gttttgtcgt aaatagttcc tagttttact
    42961 tggaatacaa cagtttttaa tttttctatg tagctttcta agtttctctt agtatcttct
    43021 ctatagaaaa ataaagcatc tgcaagtctt gcttctaaaa ctttttcatt tccagcttta
    43081 acattgtcta ttctgtaaga atcaccattt ctaacagcta taaagttagg taacagtttt
    43141 ccttctttaa gtactggaaa atatctttga tgttgtttca taggagttat aacaacttct
    43201 tttggtagtt ttatataatc cacatcaaat tctccataaa aagcagttgg atattcaact
    43261 aagtaagtta cctcttcaag taaatcttca tcaaattcaa cttctccacc taaagaattt
    43321 gccacttcta tacattgttt tcttatcatt tcttttctct tgttttggtc taaaactata
    43381 taattttttt ctaatttttc aaaataatct tctatagaat caacttctat tgtactttca
    43441 cctaaaaatc tatgaccttt tgttacatta gaagatatta ttccttctaa atcaaactct
    43501 aatactttat catttaacaa tgcaactatc catcttatag gtcttgcaaa tttaagattt
    43561 tttcctcccc aacgcatagc ttttgggaat actacagatt ttatagtctc tggtaatatg
    43621 tcttttagta cttctgaagt ttcttttcca tcttgcttta tagtcgcaaa tatatattct
    43681 tcttttccaa cttgtttaaa atatatgtca gattcgctta atcctttgct ttttataaat
    43741 cctaatgctg gttttgttaa attattttct gcatcaacag caattttctt agcaggaccc
    43801 tttatttcct cttctaaatc attttgtcta tcactcaatc cttcgactac taaagtaagt
    43861 cttcttggtg tcccatacgc atttatttta tcaaaagcta ttctattttc atcaaataat
    43921 ttactaagat tgttttttaa ttgttctagt gtactgccta caaatcttga tggcatttct
    43981 tcaacaccga tttcaaataa aagataattt ttcattattt gtcaccgtcc tttaaaagag
    44041 ggaatcccat ttcttctctt tgttttacaa aagtttctgc aacagtcttt gccatatttc
    44101 taactctacc tataaatgaa gctctttgac taactcctat tgcacctctt gcatccaatg
    44161 tattaaatgc atgagagcat tttaacacat agtcatatga aggtattaca aggccatttt
    44221 ccataagtct taatgcttct ttttcatata tatcaaacag attaaacaac atatctgcat
    44281 cacataattc aaatgcgtac attgagtttt catactcagc tttattaaat acttcaccat
    44341 aagttatttt atcattccat tttaaatcat aaacactatc aacttcttga atgtacatag
    44401 ctaatctttc taatccatat gtaatttctc ctgtctcaag ctcacattca atattaccta
    44461 cttgttgaaa atacgtaaat tgagttattt ccataccatc tagccaaact tcccatccaa
    44521 gtccccaagc accaactgta gcagcttccc agttatcttc aacaaatctt atgtcatgct
    44581 cacttgggtc aattccaatc tcttttaaac tttccaaata taattcttgt atattatctg
    44641 gagaaggttt tagtataact tggaattgat gatgttgata tagtctgttt gggttttcac
    44701 catatcttcc atctgctggt cttcttgaag gctctacata gcatacttgc caaggctcag
    44761 gtcctaatga tcttaaaaaa gtattaggat tcatagttcc tgcacctttt tcaatatcat
    44821 aaggctgcat catgatacaa ccttgctttg accagtattt ttgcaacgcc agtatcatct
    44881 cttgaaaatt cataaaaatc cctcctataa caataaagcc tctcgtctac acgaaaggct
    44941 attttaatag ttcttctaca acttttagaa tatcaaattc tataaaattt gtcaatgtta
    45001 gtgataattc ttataattat cttctcttca ttttttaaaa gtcactttat atctatttat
    45061 tttcgtcttc gtcttcttta ttcttttcag attcttcttt cataaggtca gcagttacat
    45121 ctttgtcatc ttcttttttg tcaactacta catccttcac atcttttgct gcattagtta
    45181 tcatattctt caaaacgtga agtttttctt cattcaattc acctaaatct acaatttctc
    45241 catcttcttc attttgaact tttatacgat atttacttat aacagcagct gataatccaa
    45301 ctaaagtagc taatggtaca aaagctaatc caacaactcc aactgttaaa ggaatgttca
    45361 tcatagtttt tccatctttt tcaactatta ttcgcactac actacttttt ctaagaagct
    45421 cttttaattg aaactttata ttttctccat ctttgccaaa tacttcttcc atagtttctt
    45481 tagcagattt tgctttacaa ttacaagtat tttttttatt ttctaaatat attactgcct
    45541 caattacatc tccattgcac attactaatg cttcttttgc ttctgcataa gttgctcctg
    45601 gaactctttc aaagactgaa tcaaccattt caatagttat attactactc atcattatcc
    45661 actcccttat tattttttac actttgcaat acgtgtaatg atttaaaatt aatattatca
    45721 acataaactt tcaaatactt gtctagaata ttctcaagtt catgtgttat atattttgat
    45781 actttagctt tactacatgt taaaatatca tttcttaata catattccat aagacttata
    45841 gttgttaagt ctaattttat attattatca aaaagtttac tacacttact acatagtata
    45901 ccaccttcgt agatattaaa cacagaattt tgtaaaattt tacattcaca attaatgcat
    45961 ttatttacta taggtttaaa tcctatatag tctaaaaatt ttaactcgaa tgctgctgtt
    46021 ataaacctat tgtctgtatt atcctgtgta tacaaataca gagtctgcgc aagtaatata
    46081 aatagcctat tattagtctg attttcaagt atagaatttt caactaattt tgtaatatat
    46141 gtagcataag aaaatgcctc tatatcatag gatatattat aaaaactttt tattatttca
    46201 ctttgagtaa ccttgtacat attaccttgt ttttttaagg taaaattgct ataagaaaat
    46261 aactgtgatg atgaaagcaa agagctctta ttttttttag ctccttttgc tattgcagat
    46321 acttttccaa gctttcttgt aaatagtgta agtattatat cactttcctt ataccttata
    46381 gctttaagta ctatcccctg ggtgttcagg attatcatcg tcttcttttt tctcccttac
    46441 ttcttcaatt tcttcatgta tgtttttgca atcacagaaa tataaatatg catctatact
    46501 acctgttttt ttaaaaactt cccaactgat attgttcatt tttaaaaaac ccccttctta
    46561 catttatact tatattttta gtaagaagag gataaatcat acataaagtt attaaacaat
    46621 ttttgacaat aatgccgttg ttattataaa gtaaactgct ataccagtta tatcaagagc
    46681 tgtagatata attggtgatg aaactgtaga tgggtctgca tccatttttt ttaataaaac
    46741 aggcataaac gcacctattg ttgcacctaa aaccatattt ataaataatg atattgaaac
    46801 aattaataca atgtctaact ttctcataac aaagtaaatt acaatacctg ttattatact
    46861 acacaaaaga cctgtaataa tacctacaat accttctcta accacattgc taaaatttaa
    46921 atccttatta gacaatgtta ttactgtaac agatgatgat tgagttccaa tatttccacc
    46981 cataccaatt actacaggta taaaaaatac taatggagca tatacaggat tcattatata
    47041 gtctaagtta gaaagtatta acgaagccaa caaccctcca actaaggtaa taattaacca
    47101 aggtaatcgt cctctaagtg ctgatattat ttgctctctc aatgtagggt tttctttttc
    47161 cgcaacttct ctttcatgtt ctgaacttcc tgcaaattta tacatatctt cagttgcttc
    47221 ttcttccatt acatcaatta tatcatctac tgttattatt ccttttaatt tttcttgtct
    47281 gtctactact ggaattgcta ttaaattgta tttagatact aatcttactg cttcttctct
    47341 atcttcatct acataaacag agattatatt ttcactcatc aaatcttcta ctatatttgc
    47401 gtctctagct attattaatt ctcttaatga caatactcca actagttttt cttcatcatc
    47461 aaccacatat atataataaa tagtttcagc ttcttcagct tcttctctca tatggtctat
    47521 agcctcaaga gctgtcatat ctttatttat agaaatatat ccagtggtca ttgttccacc
    47581 agcagaatct tcatcataga atagtaactc ttttacataa tcggcattct cttgattcaa
    47641 aagatttatt atgtgttctc tttcttcttc ttcaagttca ctcaacttgt ctgccatatc
    47701 tccaagagac ataagttcaa gtatattttt cgagtgttct acatccagtt tagataaaat
    47761 actaataaaa aactctacac taccttcttc taatatagaa gatgccatat ctaaaggaag
    47821 tacttcaaat aattgaattt tcatgtcttc ctctaaattt tccattatat cgaatatatc
    47881 aattatatga tattcctcta ttaattctct taactccaat actttattat tatcaattaa
    47941 tgattttact tcatataata aatcttggga agcatccagt ttcctatcca tataacccac
    48001 ctttatttat cattatatcc aaaattattt atataatttt gtaaatttct ccaattttcc
    48061 ttgactttaa cccataattg aagatttatt tgtgaaccta aaagcaattc tatatcttgt
    48121 cttgctgact tacctattcc ttttagtttc ctaccatttt ttcctattat tattccctta
    48181 tgtgaatctc tttcacagta tattacagca gatacatcta ctatttcctt atcatttctc
    48241 gctttcattt tttcaatttc aacagctaca ccatgaggta tttcatcatt aagatagtga
    48301 agaacttttt ctcttataag ttctgctatt aatactcttt ctggctggtc tgtaatcata
    48361 taatctggaa aatactttgg cccttcttct aaataatttt gtataacttt tattaaggta
    48421 tccgtattct ttccttttaa tgctgatatt ggtactattt ctttaaaaat accttctcta
    48481 tcatacattt tgattatatc aaatagctca tctttttggt ctagttggtc tattttgttt
    48541 acaactaaaa ttattggtgt cttaacactt cttaaatcct ctattatctt tctatctcca
    48601 ggacctattt ttttagaatc atcaactaca aataatatta aatctacatt tttaaaagct
    48661 tctgttgctg cctttaccat aaattcacct aatttatttt ttggtttgtg aatacctggt
    48721 gtatctaaga atactatctg catttcttca tctgtatata ctgcttgtat tgtatttctt
    48781 gtagtttgag gcttatcact cattatagct attttttctc caactacatt attcattaaa
    48841 gtagattttc ctacatttgg tctacccact atactgacaa aacctgattt gaacattaac
    48901 tgtctcctaa ctttttatct tcttgtttta attacttaaa tttatttata cttttaaatt
    48961 tattttaaat catttccaga gaaatagttt ggcaacaaat cctttatact atgctcaaac
    49021 acctctcctt tagtatatcc cgttattatt tttatatcag aaccaaactc tataattacc
    49081 tgcctgcata ttccacatgg atatgtttgc tcattatttt ctgagttatc acttgctata
    49141 gctattttat agatatcctt atcaccctct gatattgctt taaaaatagc tgttctttct
    49201 gcacaatttg ttccacctaa tgatgcacat tctatattac atccagtata aactttacca
    49261 ctcttagtta aaagagctgc acctactcta aaacctgagt aaggagcata agaatgttgt
    49321 ctggcatctt ctgccaacct taacaattct atgttatcca caacaactcc tcctgtatac
    49381 aataattaaa agttattttt atttaatact ctacattata tcataaaaat ttaattagca
    49441 cagatttgtt ttattttaaa tattttatgt acatttattt taattataga acattccaag
    49501 ctgaaatact aatatagcta tcaacacacc taacaaagct ccagcaatag tctcccaaaa
    49561 tgtatgtatt tttccttcaa ttctactttg ggcaactaat acagccatta tatatgcaag
    49621 agtagaggca acaactcttt cagtcataag tgtaattgca gttgctatag caaatgctaa
    49681 ggcagcatga ccacttggca ttcctccttt tagaggagta cctgtagaag tcaatgcttt
    49741 tacaactaca acagctataa gaaccaataa tatacatatc aaggttatat gtaattctga
    49801 ttctcttatt ttataaatta atattccaga tatatctgtc aatttatcat aaaacaaaat
    49861 atatccaact actactgaat ttagtgctgc cactagaacg cctccagctg caacatcttt
    49921 tgctatctta gcaagaacat gatattcatc agttactaaa tcaacagctt tttctatagc
    49981 tgtattaaac atttcagcaa ctacaactaa acatatggac ataagtaaca ttatcatttc
    50041 taattttgaa aagttaaaaa acaaacttat tataagaaca gcaactgaac ctaaataatg
    50101 tattttcata tttctttcaa atttaaatgt atacaatatc ccttctatag ctgcattaaa
    50161 tgctttaatt ataccttgac gagttttttc tggtttcata aaaactactc ccttgttatg
    50221 tttaacttat ttaatatgtg ttcttctttt tctctcattt cttttgtatt ttcatctgta
    50281 tcgtggtcat aacctaaaag atgaaacata ctatgacata ttaaaaaaca tacttctctt
    50341 tcaaaactat ggttatactc tatactctgt tctaaggctc tttcaagaga tactactatg
    50401 tcacctaggg attcttcttc taactcaaca tcttcaaaat catcacttaa aagaggaaat
    50461 gataaaacat cagtcactct atcaactcct ctatattctc tatttaattc atgaatctct
    50521 ttattatcta caaaagaaag actcacttca taattatcat catatccttc ataatctaaa
    50581 cattctatga ttatatcctt tatcttttca attaactcct cacttacttc taatttatct
    50641 tgtctatcat ctagtatcaa atccattcac tacacctact ttttattcat taataatgct
    50701 atatatctat attactacac ttttactttc ttttgaaagt cttttcctgc attttcgctt
    50761 ttttacgttc ttctttttta aattcttctc ttttgtcgtg cttctcataa gctcttatta
    50821 ttctctgtac caactcatgt cttacaacat ctctatctgt tagcattata gacccaatac
    50881 ctggaacacc tttaagaatc tctgtagctt gtattagacc actcttctta ttttgtggta
    50941 aatctgtttg agttacatct cctgtaacta cagctttaga gccaaatcca agtctagtta
    51001 aaaacatttt catttgttca gaagtagtat tttgagcttc atccaatatt ataaatgaat
    51061 tatcaagtgt tctacctctc ataaatgcaa gtggtgcaac ctcaatagta cctctttcta
    51121 aatacttatt aaatttatca gcacccaaca tttcaaataa ggcatcatat agtggtctta
    51181 aatatgggtc aactttgtcc tttaaatctc ctggtaaaaa acctagactc tctcctgctt
    51241 ccacagctgg tcttgtaagt ataattctac taacttcatc tcttttaaaa gcttttactg
    51301 ccatagcaac cgcaagataa gtctttcctg ttccagcagg tccaacacca aaagttatat
    51361 cattattttc tataagtttt atatattctt tttgacctaa agttttaggt tgaacagctt
    51421 ttcccctttg agttatgacg attgtcccct caagttcttt tattttttgt tcacttcctt
    51481 caagcaaaag agataatgaa taagaaatac tctgcttatc taaatgctta ccatttgata
    51541 cagtttggtg taattcattc ataagtttta atgcagaatc tacatttttt tcttctccaa
    51601 ttaaaattat attgccttct ctaagtatta catctatatt taaagtcttc tctattaatt
    51661 ttacattttc atcaaagttg ccaaataact ctctttcaaa gttaccatct gctattgtaa
    51721 atttcttttg tattatcaat tgaattagtc ctcctaagat tttaagttta attttattag
    51781 ttgttattgc tattattatt ttgactatta ttactatttt gattactatt attttcatca
    51841 gaattgtttt ggtctttatt atccttatta tcctcatcaa actcatttct tatatcattt
    51901 aatggtcttt tttctggatt ggaaggaact tcctcttcac cttcatctgg tttactttct
    51961 tcctttataa acctttctgc ttctgactta ctaagaggat aaattttagc aatattttca
    52021 ctagtttgaa ctgttattaa atattctaac atatttttat taaccttaaa gttatgtttt
    52081 acatctatta ttctagccga agctgggatt atgtattcta actcttttaa agctttttca
    52141 gataattctt tttttaactc ttctttattc ctttttactt caaccttttt tgtttcataa
    52201 aaagtactcg tttttatctt tattggaaaa gtatagtttc ctattgatag ttttttttct
    52261 ttattttcaa caacataatc tttatatttt atattttttc tcattgtaaa ctctttatca
    52321 taaaaactta gtgtatatat atttttcttt tctccagttt ttttatttac agtatctaca
    52381 taacttgcct tttttgtgga ctcataaaaa gtacttgccc atacttctgg tattgacttg
    52441 gtattagctc catttaataa gacatctccc ttttggacta tgtctccaga tttaataact
    52501 gatttaccac ttctagggat taccttttct attataccat tttttaaagc aattacatta
    52561 caataatttg attggtctgt agattttagg gattctgcct tttttgtaac agtaacaaat
    52621 atatttgttc cttttacatt gatagataaa tatgccacat cattaaattt tgacatcata
    52681 tggtctctaa cttcttttct atcaatactc ttcttataga ctcctggcct tactccaacc
    52741 ttataaagct catttctaag agcttctttt tttatacctt caggagattg tatatataca
    52801 tctgtcacaa actgtgatgt agacatcaat aaaaataaag aaacaagagc acaaatccac
    52861 atacctttgt gcttataaac tcttttgata ataaaaggga ccccagtttt ttgctttacc
    52921 tttatatcaa acttacttcc tctataaaca ttcttaaagt cttttatatc ttgtctatct
    52981 atatgaaact ccattttagt attttttatt ctagttacat tgtaaacact tatcccattt
    53041 cttataagat gatttaaaaa ttgttcgagt cctactcctt ccacaactat aacatagtat
    53101 ccccttataa aacttatcaa gtgtatctcc tcctaatcaa catactcaac attgtagata
    53161 atccctttta tacctatctc actatcagta atatacttaa gtgaaagttt atccccagat
    53221 attttaattg ttttaacttt agtctttatt cttattaaat caacttcata tt
//
LOCUS       DAEHWO010000018        53252 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEHWO010000018 DAEHWO010000000
VERSION     DAEHWO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53252
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.018"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(88..1443)
                     /locus_tag="KNP54_001343"
     CDS             complement(88..1443)
                     /locus_tag="KNP54_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBF0892249.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(1469..1738)
                     /locus_tag="KNP54_001344"
     CDS             complement(1469..1738)
                     /locus_tag="KNP54_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBF0892250.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(2028..3983)
                     /locus_tag="KNP54_001345"
     CDS             complement(2028..3983)
                     /locus_tag="KNP54_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892251.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLKDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKLVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(4166..5641)
                     /gene="spoIVA"
                     /locus_tag="KNP54_001346"
     CDS             complement(4166..5641)
                     /gene="spoIVA"
                     /locus_tag="KNP54_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBF0892252.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(5813..7108)
                     /locus_tag="KNP54_001347"
     CDS             complement(5813..7108)
                     /locus_tag="KNP54_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0892253.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDESGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERCKELIEMNNNSNENTTKVS"
     gene            complement(7292..8701)
                     /locus_tag="KNP54_001348"
     CDS             complement(7292..8701)
                     /locus_tag="KNP54_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBF0892254.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGC"
     gene            complement(8753..9892)
                     /locus_tag="KNP54_001349"
     CDS             complement(8753..9892)
                     /locus_tag="KNP54_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBF0892255.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            10211..10861
                     /locus_tag="KNP54_001350"
     CDS             10211..10861
                     /locus_tag="KNP54_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0892256.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(11018..12037)
                     /locus_tag="KNP54_001351"
     CDS             complement(11018..12037)
                     /locus_tag="KNP54_001351"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBF0892257.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(12068..12682)
                     /gene="plsY"
                     /locus_tag="KNP54_001352"
     CDS             complement(12068..12682)
                     /gene="plsY"
                     /locus_tag="KNP54_001352"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBF0892258.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(12717..14036)
                     /gene="der"
                     /locus_tag="KNP54_001353"
     CDS             complement(12717..14036)
                     /gene="der"
                     /locus_tag="KNP54_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBF0892259.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(14070..15398)
                     /locus_tag="KNP54_001354"
     CDS             complement(14070..15398)
                     /locus_tag="KNP54_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBF0892260.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(15636..15836)
                     /locus_tag="KNP54_001355"
     CDS             complement(15636..15836)
                     /locus_tag="KNP54_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892261.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(15838..16770)
                     /locus_tag="KNP54_001356"
     CDS             complement(15838..16770)
                     /locus_tag="KNP54_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBF0892262.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(16815..17747)
                     /locus_tag="KNP54_001357"
     CDS             complement(16815..17747)
                     /locus_tag="KNP54_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBF0892263.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(17802..19091)
                     /locus_tag="KNP54_001358"
     CDS             complement(17802..19091)
                     /locus_tag="KNP54_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0892264.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(19120..19812)
                     /locus_tag="KNP54_001359"
     CDS             complement(19120..19812)
                     /locus_tag="KNP54_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892265.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(19827..20588)
                     /gene="pgeF"
                     /locus_tag="KNP54_001360"
     CDS             complement(19827..20588)
                     /gene="pgeF"
                     /locus_tag="KNP54_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBF0892266.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(20585..21046)
                     /gene="nrdR"
                     /locus_tag="KNP54_001361"
     CDS             complement(20585..21046)
                     /gene="nrdR"
                     /locus_tag="KNP54_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBF0892267.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(21068..21331)
                     /locus_tag="KNP54_001362"
     CDS             complement(21068..21331)
                     /locus_tag="KNP54_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBF0892268.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(21435..22208)
                     /gene="sigG"
                     /locus_tag="KNP54_001363"
     CDS             complement(21435..22208)
                     /gene="sigG"
                     /locus_tag="KNP54_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBF0892269.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(22300..23022)
                     /gene="sigE"
                     /locus_tag="KNP54_001364"
     CDS             complement(22300..23022)
                     /gene="sigE"
                     /locus_tag="KNP54_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBF0892270.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(23047..23919)
                     /locus_tag="KNP54_001365"
     CDS             complement(23047..23919)
                     /locus_tag="KNP54_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBF0892271.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(24209..25483)
                     /locus_tag="KNP54_001366"
     CDS             complement(24209..25483)
                     /locus_tag="KNP54_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBF0892272.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(25767..26924)
                     /gene="ftsZ"
                     /locus_tag="KNP54_001367"
     CDS             complement(25767..26924)
                     /gene="ftsZ"
                     /locus_tag="KNP54_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBF0892273.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(27114..27467)
                     /locus_tag="KNP54_001368"
     CDS             complement(27114..27467)
                     /locus_tag="KNP54_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBF0892274.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(27566..28240)
                     /locus_tag="KNP54_001369"
     CDS             complement(27566..28240)
                     /locus_tag="KNP54_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBF0892275.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VDLFAK"
     gene            complement(28245..28943)
                     /locus_tag="KNP54_001370"
     CDS             complement(28245..28943)
                     /locus_tag="KNP54_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBF0892276.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(28966..29706)
                     /locus_tag="KNP54_001371"
     CDS             complement(28966..29706)
                     /locus_tag="KNP54_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBF0892277.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(29976..31202)
                     /gene="murG"
                     /locus_tag="KNP54_001372"
     CDS             complement(29976..31202)
                     /gene="murG"
                     /locus_tag="KNP54_001372"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBF0892278.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(31220..32350)
                     /gene="spoVE"
                     /locus_tag="KNP54_001373"
     CDS             complement(31220..32350)
                     /gene="spoVE"
                     /locus_tag="KNP54_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBF0892279.1"
                     /translation="MPKENLKKQIDIRVKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(32402..33757)
                     /locus_tag="KNP54_001374"
     CDS             complement(32402..33757)
                     /locus_tag="KNP54_001374"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBF0892280.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSDNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(33776..34744)
                     /locus_tag="KNP54_001375"
     CDS             complement(33776..34744)
                     /locus_tag="KNP54_001375"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBF0892281.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(34785..36158)
                     /locus_tag="KNP54_001376"
     CDS             complement(34785..36158)
                     /locus_tag="KNP54_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBF0892282.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVIDGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(36325..38304)
                     /locus_tag="KNP54_001377"
     CDS             complement(36325..38304)
                     /locus_tag="KNP54_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBF0892283.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(38316..38663)
                     /locus_tag="KNP54_001378"
     CDS             complement(38316..38663)
                     /locus_tag="KNP54_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892284.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(39144..40079)
                     /gene="rsmH"
                     /locus_tag="KNP54_001379"
     CDS             complement(39144..40079)
                     /gene="rsmH"
                     /locus_tag="KNP54_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBF0892285.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(40109..40855)
                     /locus_tag="KNP54_001380"
     CDS             complement(40109..40855)
                     /locus_tag="KNP54_001380"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBF0892286.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(41249..42535)
                     /locus_tag="KNP54_001381"
     CDS             complement(41249..42535)
                     /locus_tag="KNP54_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBF0892287.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(42550..43815)
                     /locus_tag="KNP54_001382"
     CDS             complement(42550..43815)
                     /locus_tag="KNP54_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBF0892288.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            44131..45228
                     /gene="ychF"
                     /locus_tag="KNP54_001383"
     CDS             44131..45228
                     /gene="ychF"
                     /locus_tag="KNP54_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBF0892289.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            complement(45707..47986)
                     /locus_tag="KNP54_001384"
     CDS             complement(45707..47986)
                     /locus_tag="KNP54_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0892290.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(48257..49711)
                     /locus_tag="KNP54_001385"
     CDS             complement(48257..49711)
                     /locus_tag="KNP54_001385"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBF0892291.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            49875..50744
                     /locus_tag="KNP54_001386"
     CDS             49875..50744
                     /locus_tag="KNP54_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892292.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNMHDIESIKSFIEQINISESNTEFGNEILRNTLFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(50957..53029)
                     /locus_tag="KNP54_001387"
     CDS             complement(50957..53029)
                     /locus_tag="KNP54_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBF0892293.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENTLVEKIDSLTNGELLDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
BASE COUNT        16833 a         9692 c         5581 g        21146 t
ORIGIN      
        1 tcattatctt atataatatt taaatgcata ggcttcttta atttaaccat ctaaatattt
       61 aattaaatat tattatatgt aatataacta atttttaaat gaatgtatag gagctggaat
      121 ccttcctcct ctttgagtaa ataattcaga tgaatttgta tttataggca ttactggtgc
      181 tcgtcctaaa agtcctccaa attctaccat atcacctaca tcacatcctg gggctggtat
      241 aattctaacg gctgtagtct tattattaat catacctatt gctgcctcat cagctatcat
      301 ggctccaagc gtacctgctg tagtatttcc tggcacagct atcatatcaa gacctacaga
      361 acaaatagca gtcattgctt caagcttatc tatacttaaa gcacctttaa taacagcatc
      421 aatcatacct gcatcttcag atactggtat aaacgctcca ctaagtcctc caacatgtga
      481 acatgccatt actccacctt ttttaacagc atcatttaaa agtgctaatg ctgctgtagt
      541 cccatgagta ccaacaactt caagacccat ttcctctaat atatttgcta ctgaatcacc
      601 aatagcaggt gtaggagcta gtgataagtc tattatccca aatggaacat ccaatctact
      661 agaagcttcc tttgccacaa gttgtccaac tcttgtaatt ttaaatgcag tctttttaac
      721 tgtttctgaa acaacatcaa aaggctctcc ctttactttc tctaaagctc tcttaacaac
      781 accagggcca cttacaccaa catttataat tctatcagcc tcaccaacac catggaaagc
      841 tcctgccata aatggattat cttctactgc attacaaaat actactaatt ttgcacaacc
      901 aaaacctttt gcatcttttg ttaattctgc agtttctttt atgatttctc ccatttcttt
      961 cactgcatcc atatttatac cacatcttgt agaacctaca tttactgaag cacatacttt
     1021 attagtactt gctagagctt ttggaattga cttaattagt atcttatcac cttttgtata
     1081 tcccttttga actaatgctg agaatccacc aataaaatct atacctaaat cctctgcagc
     1141 cttatccaat gtctgtgcaa actttacata gtcattttca tctgttgcac ctgcaataat
     1201 ggaaattgga gttactgata cccttttatt tacaattggg ataccaaatt cacgctctat
     1261 atcttttcca accttcacca aatctttagc agaactcata atcttattgt atattttttc
     1321 tctagcttta tctccatcag ggtctataca atctaataaa gaaatcccca tagttatagt
     1381 tcttatatcc aactgttctt catctatcat ctttattgtt tcaagtatat ttcctacatt
     1441 cactattatc acctcccctt actgtctact acagattatg cattgaatta aatatttctt
     1501 ctcgctgaat ttttacatcc actgataatt tcttacctct ttcaaccaag tcctcaaccg
     1561 ttttctcaaa agaatttaat gatttctcta aatcaactat cataatcata gtaaaataat
     1621 cctgtaatat tttttgtgat atatctacta tgttgatatt ttgcttgtat aattcatcac
     1681 taattcctgc cactatacct ggtttatcct ttccaattac tgttaaaatt gctttcataa
     1741 taatatcctc ccttattttt ttataaatct tatattttta caaattgaac tatgttttaa
     1801 catatatttc atttatttgt tagtaaacca ctttttatgt atatatttaa tatattttaa
     1861 tacctataca ttcatttgtc aatttttttt caatattcta ttatttttat actatttaga
     1921 aaattcatat attatatatg ttttctcaac aataaataca gttttcataa taatgaaagg
     1981 tattacttag caatcgcatg attttctaaa taataccttt ctaaaaatta tttttttaat
     2041 tttatgaatt taattatact ttttctagta tcaggattta caattaatat agaaccaatc
     2101 ataattggtg ttagtataca aaataaaaaa ataatatctt tttttagatt atattcttta
     2161 gattctaatt tataattatt atttattatt ccatcataat cacttatatt tgacttattt
     2221 ttatttgtat cttgattttt gttagaaata ctttccctat aaggaaaaga atgttcattg
     2281 gtaccaaata ctaattttga gcttaaatca taattatcat cattttctgt aattgaattt
     2341 ttattgtaaa atcctttttc tttatcagaa ttattttctt tattaccgtc tttaggtata
     2401 tcatgaggat ttttattttc attgctatca gtacttgatt ctacatcatc tttaggagta
     2461 tttggttgtt tctcatcaga attatcattt tcattattat tattttcatt attattgttt
     2521 tgattgttat tactatcatt attttcattt ccattattcc catcttgatt gttatcatcc
     2581 tcatctctat ccgggtcgtc tctacctcct cctccacggt caccatcaat atcatcattt
     2641 tcccgttcat catctggtgt ctcttggttg tctccgcctc ccattataaa tcctggttta
     2701 aaaactatat ttgaataccc ttcttttaat cctcctacca cttttactct aaaacaacgc
     2761 aacttaaaat cttcaaaaaa aagtatagct tgatctctaa tatcctcctg ttcttcagat
     2821 atccaattga ttccatcgct tgaatattca acaaaaacct tacttgcact atacggcata
     2881 tcataaaata aaacagctac atatccattt tttgtatttt gaaattccag ttccaaattg
     2941 tctattggtt ttttctctat aacagataca ttcaaaatag gaactacatc atcatttatt
     3001 ataatttttt ctttatttaa catttctgtt ttaaactttc ctgttatatt aaaattttct
     3061 cccttttcca acttttcata ataatcagta aaatcccatt ctacatctat atcaagtcga
     3121 ttaccactag atgtttctaa taccatatat ttgggaaatt ttatattttc tattttatca
     3181 tctttactta cttttatttc atcactaaat acaccaattc ccctatgaca acatttcaca
     3241 atatcatagc cagaatcttc agctatagag ggtataagct cattataatc atcaattata
     3301 taaactttct tactttctga tataattgat tgtgccaact tattattatc ttttagtaac
     3361 ccactttcat tgttgctact atatgctttt attgaagttt cttctatctc aacatcacct
     3421 ttagaataaa cacctatagc atgttctcca ttcacttcaa tatccttatt tagtattcta
     3481 atatcatttt cagtataaat tcctattgca tctttcccat ttgcctttat tttttcaaca
     3541 gattcgtagg atgatttaat atgtaagtct cctccttctt caacgtataa ggctgtccca
     3601 tcagtagcaa ttatgttgtt tataccaata cttatacttc caccattttc tatatgtatt
     3661 actccttctt ttcctccttc acctattata ttcaattcat tatcatcaat aataaatctc
     3721 ccatgatttt ttatcaatat tttatatttg ttggtatcta ttgtaaaatt actgtcataa
     3781 ggaatataaa atctaaactc ttcatctatt accatatcac aagaaagagt ataaactatt
     3841 tcttctttat tatttttatt ttcttgaacc cacctttcaa aatcttcaag acaattttcc
     3901 tcttgtccaa aaactttatg tggaaaactt ataaaacaca aaactattat actcataaaa
     3961 ataaatatct catacttttt catcttacac tcctagaaat tttttagctt tgaaacaatc
     4021 tgtcgaaaca tacacttcac ccactataat ttttccacaa ttatcaatta ttgtcaattt
     4081 ataaaagtat ctttattaat tgttataaat aaaaagctac ttactaaagt aaacagacgt
     4141 ttcactttaa taagtagcta tatttttata acaaaatagt tataatatta gaacttcctt
     4201 catttacaat tttttgtaaa gtcttttgca ttttaactct tatctcttct ggcatagtat
     4261 ataatttact ttgtaattgc tcttttacta agtcatgtag tgatttacca aacatatttg
     4321 attcccataa atctgctggt tgctcttcaa atacttccat aagatatttt atcatctctt
     4381 caccttgatt ttgatttcca actattggag aaacctctgt agatatatct gcttttataa
     4441 tatgaagtga tggtgcattg gcttttaact tgataccata ttgttttcct tgtttcatta
     4501 tttctggttc ttccagacta agttcttcta aggaaggagc tactactcca tatcctttta
     4561 tcttggcatc tattaaagca ctttctattt tatcatactc atttttaact ttagatagtc
     4621 tagttatcag actaagcagt tgataatctc cttcaatttt aaatccactt ttttcttcaa
     4681 ggacattata gaataaatct tgctttgtct gtaaatcaat atttataaca ccttctccta
     4741 gctctacatt atcaacacct gtatcttcca aaaactctaa ctcagaaaat ccttgtataa
     4801 taccttctat atcccttatt ttacctatat ctataatact ttgttttaat gttgttatta
     4861 tgctactttt tatccaatga tttctttcaa gaccttcaac ccattttggt aagttgattc
     4921 ttatttctgt aagtggaaaa tcatataata cagcttccat aacctcctct atatcttctt
     4981 cttccatttc aaccacattc attggaagaa ctggaacttc atacttttct tccaattcac
     5041 ttctaagcat actcgtttcc tcactttttg gacttaacgt atttaaaacc actgcaaatg
     5101 gttttttaag atttttcaat tcttgtataa ctctctcttc tggttctaca tagctttttc
     5161 tgtcaattcc agtaactgaa ccatctgtca agacaactat ccctattgta gaatggtctt
     5221 ttataacttt tttagttcct atctctgctg ccttttcaaa tgtcatagct tcttgtgacc
     5281 aaggagtgga tactaatctt tgttttccac cttcctcatg ccctaaagct ccttcaacta
     5341 tgtatccaac acaatctacc attcttactt ttaaagatac tgtgtctttt atttttattt
     5401 ctacaccatc tgctggtaca aattttggtt ctactgtcat tatcgtttta cctgaaccac
     5461 tttggggtat ctcatctctt gttctatcct ttttaaattc attgtctata ttaggtataa
     5521 ccaacttttc cataaatttt cttataaaag ttgattttcc tgttcttaca ggtccaacta
     5581 ctccaatata tatatccccc tgagtccttt tggatatatc ttcgtatatg ttattattca
     5641 tattattcct cctatacatc taatcttatt aaattatatt tagagttaag ggttaatatt
     5701 cttaaaatag aaaaataaag accagcaata ttaatttaat ttatatatag aaatttgtaa
     5761 atttcaatgt aaattaaatt aatattgctg gtccaaatag tagtgtatta tattaactga
     5821 ctttagtagt attttcattt gaattattat tcatctcaat aagttcttta catctttctt
     5881 ttgtcatgtt catccatata aatgtaaaca ccaatccaat tatggctact atagtaagaa
     5941 ctatgaagta gtacctatat ccagttacac ccggaaatgc atccaatatc ttccctgctg
     6001 ctaaaggaca aagtacttct ggaagatatc ctaacgtagc aactattcct atagcagttc
     6061 ctgatattga taatgaataa ttaccttctt caagtaacga atagtgtaaa ccttgaattg
     6121 catacataga tacatatatt gcaacacatc caatcaatag tatataaatc atagatgatt
     6181 ttgttggtgt aaatattaca cctaaaagac ctgcaatcat aagtataaat ccataagata
     6241 taatctttga tgaaccaact ttatctccaa gtaatccaga agcagctgat gctactggtc
     6301 tacaatactg agctaatatt gagattgcag atgcaaacac cacagtagct ccaaatgctt
     6361 cagttgaata aggcgtaaaa taataaaatg acatattagc tgaatatgaa caaaacatta
     6421 ttattgttat tatccatgta tgaggcattt ttattactgc aaaaaaggct tctttatcaa
     6481 attttgctga tacctctttt tcattatcct ttaatttgaa aaatactaat actccaacta
     6541 ttacatttat tgctgagtat aatactataa tagctgtaag accagattca tcacttactt
     6601 ttgatgaaat atacccaaat agtatcaata ctagagatag atgaattgca ttggtaattc
     6661 cacgaccact ttccataaat ccaaaagctt ttccttgttc attttcagat gctaacattc
     6721 taacagcttt tacaagagct ggccaaaaag taagtattgt tgttattccc cataaggcat
     6781 ggattaaaaa cacaacaata tatggaggat aaagtgttaa tacaagacca gatattcctg
     6841 taataattaa agaacctgaa agcaattttc tggctgaaat acggtctgct aaaaaaccac
     6901 caaaaaggta tgataccatt gcaagtagac cataaatgct tcctaagctt cccatttgtg
     6961 tatttgtaag attaaatgct tgtgcaaaag tatcataata ataattcttt aaatatggta
     7021 aagcatatat aaatgctcct gctacaaaga gtattatcaa gactttgaaa tttttccaaa
     7081 tgcttggttt atttacttca actgacatac ttcctcctta tgtaaatacc tgtaaatttt
     7141 cataataatt aattattgct tattttattg tttattcaat atttaggaat atttattaat
     7201 atattaggtt aatctatcaa taatttatgg tgagttatga gctaaaagta aactctttta
     7261 gctcaccata ataattatat ttttatttat actaacatcc agagttatta gatatctttt
     7321 tttcatagtt cttccatagc attaaacctg ttattataac aaaaagacct cctcctatca
     7381 tttcaatctc atagattata ttatctttta aagtctccat aactggtgcc gttgagaaaa
     7441 gtatgccaac tacagttact acaagtacca ttctggcaat attgatacaa actgaatcac
     7501 tttttgcaat tgaatatggt ctttcttcat ttggtcttgt ctttctaagt ctaatataag
     7561 atgtaaaaag caagacatat ggaaataatg ctgttaatgc tgtcatagta acaagaacat
     7621 tgtatatatt atctactgat ggtaataagt ttgttcctac aagaagtaga ctcactatta
     7681 tagcctgaac tattactgca tttgatggta tattgtattt atttgtaaca gtcaattgct
     7741 taggaaatac accttctctt acatttccaa aaagcatctt tactggacct gctatataaa
     7801 gtattaatgc tcctagtact gataaagtta ttccaaatgc tactattctt ataaaccaac
     7861 ttcctatacc taaatcttgt gcaactttag ctaatgcatc tagtatccct gtagatgctg
     7921 caattttatc tggaggaagt atcattgtta ttgctactga acctaagata tagattcctc
     7981 ctattaaaac agccacagtt aatatagctt taggaaagtt tttcttagca ttatccattt
     8041 cggttatgaa attagcagtc gtttcagctc ctgataatgc aaatattata gcagatatag
     8101 aaactaatga attggcatct atttttggta ttatattttg gattgtatat atcgatgctg
     8161 atggagcttt tttgagaata actacagaca taaatgccat cactataagt aatatagcag
     8221 gaattgtaga acctaatgct cctgtattcg taaaaaattt tccaaatgcc atcccacgag
     8281 tacttactaa ggacaacagc caaaatatta tgagtgaaag tgctaaaata aacatcttat
     8341 tgtttgataa atctggattt ccaagcatat atgcaatatt tatcgctaaa aaagtcaaga
     8401 aagaagaata ccaaaatatc tttgatgtcc aatttagcca tgacaccata aatccccact
     8461 tctctccata agcttgttta acccattctc caagtccacc atcttttgga tatgttgcag
     8521 ccaactctgc acatataagt gatgcaggaa caaagaatat aaaagcaaac aataaccaaa
     8581 ctggtataga accaagaccc aatccaaaac tagaggcagt agatttagct atccatctaa
     8641 tcccaaatag tgctgatata ttcataaata ctaaatccca aaatccaatt ttctttttca
     8701 ctgtaattcc tccaatttca aatttattca gactcataca caatgtattg acttaaatat
     8761 caagtataag ttcttcaaca cttcttggat aattagttat aattgtagca ccattcttac
     8821 ctactattgc tgtatctgag tgtctaaatc ctccaactcc aggtatatat atccctggct
     8881 ccatagaaaa taccattcct tcttctaata ttaattcatt gtcaaatctt aaatatggct
     8941 cttcatgttc tgataaacct aaaccatgac caattctatg atttgaatat aactctagac
     9001 catactttgc aacaacagct cttgctgctt catccaccat tcttgctggt ataccagctt
     9061 ttattgtatc taatccagct tgttgagcct ctactgcaat cttaaacact tctttttgtc
     9121 tttctgttgg tttgcctata ataaaagttc tttcattttc tgctctatag ttttcatacc
     9181 aaacctgtct actatgtatt actatatctc ctctttgaag tattctagta ttggaatcta
     9241 aatgaggttg tgctgttcta tcaatccctg aacaagtcca gtttgcaaat cctatatatg
     9301 tatcaggata attttcagaa acatatttta gtaaagcatt atcccctgca acgtcaaact
     9361 ccaattcact catcccaact ctaacatttt ctaaagaccc ttttattcct atatcagata
     9421 ggtaacctgc tatcttcaaa aattctattt cttttgcatc ttttacatat ctcatttcaa
     9481 atattttact tccaacatct ttgatagcaa atgacttatc agttatatac tctgaaaagc
     9541 ttgcagatac tatatctttt tctattccaa cagttgttcc tttagggtat ttatttaaaa
     9601 ttatatctaa gtaatgttta tgtgatattc catgttcttt catttctggt atttcataat
     9661 acacatatac attatcaact tttgcaactt ctttagcatg taattcttct aatccaggta
     9721 ctattaattc tattttatct tgagttacta ctgttacaat tggtctagaa taagttattg
     9781 ctttaaatcc actaatataa aattgattgt ctggttcaaa tattaaagca atttcaatgc
     9841 ttttttcatt catgtacttt ctcaatcttt ctagtctcat attatttgac ataatgcacc
     9901 tctttcttaa tattcagata atttattcaa tacaacaagg atgaatatat tattttaaaa
     9961 ttcttaatat ttttagtact tgtcgtattt gtatgtaaat taattttatt tgtgattatt
    10021 ttatcataat catgattatt ttgtcaatca tgattttatt ttaaaaaatt ttttatattc
    10081 tagtgatttt aaattatcta aaatataacg agtatacatt gtattttgta atattattct
    10141 tgatttatgg taagtttaat gataaaatca cgattatata aactatattg attatttgta
    10201 ggtgaataaa atgacaaata aagaattaca aaagaaaagg atattgatgt atttcataga
    10261 agctgctcaa aatattatgg aaaacgaagg tatagaaaat attacacttc gtaaggttgc
    10321 agatatggct ggctataata gttcaactct atataaatac tttaaaaatt tagaccattt
    10381 aatatcattt gcatctataa aatattttaa agattataac ttgaatattt caagatgtat
    10441 agaaaatgtc aatgatgaat ataagaaata tataattatg tggaaattat tttgtaagca
    10501 ttcttttgat aatgctcaag ctttttacca ggtatttttt aacttgtcta gtgatgaact
    10561 tagctatata acaaaacaat attatgatat gtttccagaa gatttaggta ttcatgatag
    10621 tgacatatct ttaatgatta caggagaaag tataaaggaa agaaataaga tactattaaa
    10681 caatcttgta gatactggat atataccagc taaagattta gacataatca atgatataat
    10741 tatttctttt tatcaaaatc tattattctt aaaaaagaac acaggaaaaa attctgatga
    10801 tgatgaatta actatgaaaa tgatttcttc tattgaatac ataataaaac atgctaaata
    10861 aaattaaaat atggctgtct caaaatagag ataagccttt tttattgttg aaataataaa
    10921 aatatattta atttcatata aaaaagagtg cctcgtaaac taaaaagttc attttgagac
    10981 acccctaaaa taaatttatt atttattata caatagttta tatatcatca cctaaaacta
    11041 cttcttccat ttcatgcttt ttacttctca tcattagttc tattccaact tctttaggat
    11101 ttgaaccttt ctttattaca gaatatatag cattagttat aggcatatct atatctaatt
    11161 tttcagcaac atcatgtgct acttcagtag cagttatgcc ttctacaacc atctttactt
    11221 cttttaaagt atcttctaaa ctcatccctt tacctatgag tataccagct cttctatttc
    11281 tactatgcat acttgtacaa gtaactatta aatctccaat acctgaaaga cctgcaaagg
    11341 tagacatatt agctcccata gcaattccaa gtctgctcat ttcactaata cctcttgtca
    11401 taagggcagc ttttgcatta tcaccatacc ctaatccgtc acatatccca gctccaaatg
    11461 ctataatatt ttttaatgct cctccaagtt ctactccaac tatgtctgga ttcgtataaa
    11521 ctctaagttt agggctcata aataaatctt gtatcatctg tgctattttt aaatctttag
    11581 aagcaactac tacggtagta ggaatatccc ttgctacttc ttcagcatga gatggcccag
    11641 atagtattac atatggattt tgtggtaatt cttcttcaca gacttgagat aatctaagcc
    11701 cagtcccttt ttcaagacct ttagctacat taacaataac ttgtccttct tttataaatg
    11761 gttttatttt ttggcaagta cttcttacag cctgtgatgg aactgctaaa actattacct
    11821 tacaatcttt tatagttttt tctatatcag tacttatagt tatattattt ggaaataata
    11881 ctcctggtaa atagtctgta ttttctttag ttctgtttat ttttttagct tgttcctctt
    11941 ttcgagtcca catgctcaca tcattacctt tttttgcaag ccctaaagct aatgcacttc
    12001 cccagcttcc agtacctaat acacatactt tctccatgtt taacaccacc tgagtataat
    12061 atatttacta ttctttcttt tgaccaattt ttctctctgt cccatttaat aatcgcttta
    12121 tatttgctct gtgattatat attactgatg cagttaagaa cagagctact attaaaccag
    12181 ctttattttt taccataatc ataaatattg gtgaacatcc tattcctaca acagaaccca
    12241 atgaaacata ctttgttata gctaccacca atataaatac tgctagacac attagtgtta
    12301 ttactggatt tacagctagc attgccccta gtgaagttgc aacacctttg cctcctctaa
    12361 atcctaaaac cgctggccaa ttatgacctg ctacaacaca tataactgcc agatatccag
    12421 ctaaaagagt atctattcca accaatcttg ctgcaaattc tgatattaaa acagccatta
    12481 cacctttaag aacatcacct aaaaatgtca ttgctcctgc tctttttcca agtgtcctaa
    12541 gtacatttgt cgaacctgca ttaccagaac cttgagtcct tatatcaacc ccagcaattc
    12601 gctttgcaac tatgtatgag gtagatatat ttcctaaaag atatgcaact acagcaataa
    12661 ttatataact aaatatctcc actgaatttc ccccctttag ttatatttta agatatttat
    12721 tttttatttt tttgtctata ctcaaacttt atggaagttc cttcaaatcc aaaattttct
    12781 cttatcttat tctcaaggta tctttgatat gagaagtgag ttaaatcctt atcatttata
    12841 aacaatgtaa ttttaggagg tctaatgtca gtttgagtcc catagtaaat ttttaatctt
    12901 ctacctttgt cagatggtgg ttgatttaac attacagctt ctccaattac ttcattcagt
    12961 gctgaagttg atattctctt agaatgttca tttgacacat attcaactgt atctagtatc
    13021 ttgttcattc tttgattagt ttttgcagaa acaaatacga ttggagcata catcataaat
    13081 ggaaattttt cttttatatc ttttgtgtaa ttgctcatag tcttattatc tttctctatt
    13141 aaatcccatt tattgattac aaatatgcat ccttttcctt catcatgtgc tatacctgca
    13201 acctttgtat cttgttctgt tacaccttct aaggcatcta ttactatcaa tactacatct
    13261 gctctatcta cagcactcat agcccttatt acactgtatt tttctattgt ctcatatatt
    13321 ttactttttc ttctaagccc tgctgtatct attagaagaa atttctgtcc atttttttca
    13381 aaataagtat caattgcgtc tctagtagtt cctgcaattg gacttacaat tactctttct
    13441 tctccaagta tcttattgag tatagaactt tttcctgcat ttggtttacc tgttatagct
    13501 actcttatta tatcttcttc atactctgta tctaatcctg ctggaaaatt ttcaactatc
    13561 tcatctaata aatctccaaa tcccatacta ttggctcctg aaactgcaaa aggcgttcca
    13621 aatcccaact cataaaaatc gtatatatta tcaaattgac tttgactatc aatcttatta
    13681 accactaaga ttactggttt ttttgtcttt ctaagcaatt gtgcaatttc tttatcagca
    13741 gctgttattc cagctttacc atcaactata aaaagtatta catgtgacat gtccattgca
    13801 agcatggctt gatttctcat ttgagataat attatatctt cgctatcagg ttcaattcct
    13861 cctgtatcca ctaatgtaaa atatttatct aaccattcta cttcagcaaa tattctatct
    13921 cttgtaactc caggtgtatt ttcaactatt gatatccttt ttcctgcaaa tttattaaat
    13981 attgtagact taccaacgtt tggtctccca actacagcta caactggcct acttatactc
    14041 attttatttc tccttccatc ttttgttttc tattttaaaa ttttatccac aaaatctttt
    14101 ccttcattca aacaagggat aatttttatt ctcataagtt cttctaattg atttaattca
    14161 atattatcta agaaaatttc ttcatctgct tttagcatac ttcttgttat ataaagagct
    14221 tctcctaatt ctttatcttc aagttgttct tttaaatcct tagctgttaa aagacctgat
    14281 acagttattg tctctccaaa aaacttgttt ttgatttcat atacatttac ttgaagattt
    14341 ttaaacttgt ccatcatagc atctgccata ctctgtataa attcatatgc agaatgacca
    14401 gtagctattg atactttctt ctctcttttt agaatcttct caggcaatat atttagatac
    14461 tcttcaatct ctgtttttaa cttacgtatc atacctacac catcttcaaa ctgtaaaaaa
    14521 ccttcatatt cttcatatcc aggcaattca ctattagata gtatataaaa ttcatctgat
    14581 aaaaatgcaa atcgagtacc taatttttca agatatttct gttgtatttg atgtatttgc
    14641 tctatagttt tacttgcgct cttatcatta aatatattta attctactag attttctcta
    14701 tgctttgtaa tcccaactgg aactatcgca acactgttta catacggata aagttgagct
    14761 agttctttta ttgttctatc caattccttt ccatcattta tacctggaca taaaacaatt
    14821 tgacagttca tttctatatg agcatctgcc aatctcttca ttataccata taattttcct
    14881 gcaaatttat tgcttatcat tttttgtctt aactctggat tagttgtatg cacagatata
    14941 tttataggac ttattctata ttttataata ttatttatat cttcttcact catatttgta
    15001 agtgtgacaa aatttccttg taaaaaagat aatctcgaat catcatcttt aaaataaaga
    15061 gtttctctca taccttctgg caattggtct ataaaacaaa acatacactt atttctacag
    15121 cttttagctt ggtcaattat cggatttgta aattcaacac ccaaatcttc atcatagtct
    15181 ttttctatct cgtatatgta gacttcgcca tctttttttt gtatttctac atctaaatat
    15241 tcatcactta gtaagaatct atactctatt atatcatgta ttggctgttc attcacagat
    15301 ataagtaaat ctcctacctc tatacccatt tcttctgcaa tactatcttt ataaacctta
    15361 cttataatat tatttacttt ttttacattt acttccaata ttttcaccac tcttttgtat
    15421 tcatcaatgc ttattataat gtattttaat atgcaattta tttatttatt atattttatg
    15481 atagcatttt taagcatttc atgtcataat aacacatttt aattctaata gtcaatataa
    15541 gtaaatagct ataaaataga ttagaacaaa taatattcaa atttaagttt cttaaaaatt
    15601 taaatattat ttgttcttaa aaaaatttta taaatttaat gttttactat gattaacgtc
    15661 ccatttgtca tatcatgaac cattccacct acacactttg acatcaacaa tgccttattt
    15721 tgtaagtctt tctcatcatt tgcataaaat attggacaac ctccaccatt tttcatattc
    15781 ttatcaagtg taactatagc tagggtatat tcatttaaac ctatatccat tcccatctca
    15841 tgcacttcct ttctttccta ttttataatt ttttagtgat aagttttttc ctttagagct
    15901 tgaaagtatt gggcatgact ttacagcttc cattactttt tccacattct tatctactgg
    15961 taaataagca atcattatac tttcatcctc tttatttctt ctaggtaatg gtacgaatga
    16021 aggttctcca taatctccat ataaacctaa ccttgaatat atattgtata ctattgcttg
    16081 tctttgaccg gagtcaaata atattcctgc attagcataa tccttatttt taggaattat
    16141 ttgtattcct acacctctat taatatatac ttctctatcg ctttttagac ctatatttgt
    16201 tatacctttt aaatctccca cctttagtat agattcgtcc acaaaactaa tttcagcagg
    16261 cattacatca gctatgtctc caatactttt tctagtaaga agttttttta atataaaggc
    16321 taacactaat ccacaaattg aacttattac caaactcatc ccttcactta ttttcgtttc
    16381 tgcaagtatt acataataca atcctattgt taaaaaagat gtaactatac acatataatt
    16441 tcttacttca taggttctag ctatctcttc tatgaatgca gctcctctct ttacaagttg
    16501 aacttcctct aaattttgca atgtatttct tctatttgct ctcacttgtc taaattgttc
    16561 tgctgctaga gataaaaaag ttatagatgt ataagaacga tttataagag ctggaaccaa
    16621 taatgctcct aatgaagaag cgacgaatgc taatataagt tgagatagta aaacatttgg
    16681 ttgcgttgga tactgttttt ggtctaaatt caacattata attctagatg ttataccaat
    16741 aataacagca acaaaaaata ctctatccat taaatcactc ctaaaatatt taatttgaaa
    16801 ttttacatgt aaatctacaa agtctttcta gaaaaatcac tctgctttcc ttttgatgtt
    16861 tctatgatag gtgtactttt cactacatct atcatgacat ctatatcttt gagtattggc
    16921 atatatggta taaccacagt acttttttct aaattggtct tagatatagc aacaatatca
    16981 acctcatcta catctctatc tatccccata tgaataaata gattatgtat tatagcttgt
    17041 ctttgcccta tatcatttac tattccaaat gcacctaaat ctcttggtat aacttctatg
    17101 gccagacatt catttctata cttttctctt gtactttcta gacctatgtt agttattatt
    17161 acaccattta ccattaaaat aggtccttca aaacttattt ttgcaggaac tatatctgct
    17221 atatctgcta tactgttcct tcttaaaaat cttctaaaaa tcaaaccaac aatagctcct
    17281 gacacaatag ctaggattgt gcaataaaaa aagctaaggc catactttct tgcaaaaacg
    17341 atataaacta tcgaagatac cagtgcagaa aaaagactta tataacttct agattcatac
    17401 gtagatgcta tttcttcaac gtaagcgtct ccttttggta ctaattcttc attatcgata
    17461 ttctttagtg ttattctttc ttgttctgca agaccttgaa actgttgtat tgctactgca
    17521 aaaaatgtca aggctgcaaa ctccttatct ataagtgcag gtaatgctat agcacctaac
    17581 gaagctgaaa gcccagatat aattatctgt tctaaataat cttgtggtct tgatgggtat
    17641 tgtttgtctg taactcttaa aactaatcct ctacataata ttcctacaac taatgcaact
    17701 ataaaagagt gtctaaataa atttgcattc aataaacttt cttccatttt ctcagctcct
    17761 tctcttatat agtttgtgca aaaaacaaaa aaaattccct tctatttaag gaaatttttt
    17821 tgtaatattg taactataaa ttcgctacca atgccaagtt cactttttac ttttatacat
    17881 ccatttagtg atttgactat atgctttgtt atagccaatc ctaaacccgt tcctcctaca
    17941 tccctacttc ttgctttatc taccctataa aatcgttcaa atatgcgttc tacatcttct
    18001 tttggtatcc ctacaccatt gtctataact ttaattacga ttttttcttc atcttttaac
    18061 actacaactt gtacaatccc attatcttgg gtatacttta tagcattatc aactaggttt
    18121 aagaacactt gctttatata gtctttattg gatagtatac ttattgattt atcatcacat
    18181 ttatataaaa cttctatatt tttttcacta gctgaatgtt gagttatttc atatacctct
    18241 ttaaatacat catatactac aacattttcc ataagaagag tatctttatt ttctacaaat
    18301 gataacagca atatatcatc aatcaacctt tttaatctat ctgattcgct ttctattatt
    18361 tctaagaatc tatttctagt attcacatct atattttcat ttgactttag tgtttcaaca
    18421 aacccactta tagatgtaag tggtgtttta agttcatgac ttacatttgc aacaaaatca
    18481 cttctcatat tttcaagttt aactttttta gtaatatctt ctatatttac tatcgaacct
    18541 attattacgt tgttagtatt ctgaagataa actgggtcta cttttatctt atatacgata
    18601 tcatctttag tagtaatatt agcagtttca ttatctttag aaccaataaa ttgaagtatt
    18661 tgttttaata tttcttcttc ttttattaca acattaatat tatgaccttc aactaattga
    18721 tttggttcac tctttatcat ttcttttgct tcatcattta tcagaagtat atttccattt
    18781 acatctatag ccaaaattcc atgagatata ctctttaata tagaccttaa ctgtaaatgt
    18841 ttatactgta cttcttctaa ggttttatcc atattcttta tcatatgatt aaaatttcta
    18901 gctaattcgc caagttctcc tttggctgat atgttaagcc tagcatgata ttcattatta
    18961 cttacttttt ttgagacgta tataaactct tttaaatatt tccttaatgt tattgtgtat
    19021 cttacagcta atataacaat ggctatggac aacataacaa taaaaaaata tatactattt
    19081 aaatcttcca caagataaca ctcctaaaat ataacctttt taatctattt tgtatcctac
    19141 acctcttata gtctctatat atttttccga tttatcttca tcttctattt tttttcttaa
    19201 atatcttata tgaacatcta ctgttctagt ttctccatag tattcatacc cccatatttt
    19261 atccaaaaga taatttcttg aaagtacttt tcctttattt tgaattaata attttaacaa
    19321 ttcaaattcc ttaagagtta actctatctt ttcagagcct ttggtaactt catgttttga
    19381 taaatctagt tttaaattac ctgtagtaag tatattgttt tcttcaccta agctagtcaa
    19441 attatatctc cttaaaacag aactaatcct agctaacaac tcttttatac taaatggctt
    19501 agttatatag tcatcagcac ctatttcaag cccttcaacc ttgtcatttt ccatattttt
    19561 agcagtaagc attataacag gaatattttt taagtcctta tcacttctta tttttctcaa
    19621 aacttctatt ccacttatat ttggtaacat ccaatctaaa agtattaaat ctggtttaat
    19681 ttccttagcc tttataaatc cgtcaaatcc atcatatgaa taactaactt cgtaatttga
    19741 cacctccaaa ttgaatttta atagctcaac tatatgcatt tcatcgtcta taacaagcac
    19801 tttagtattc attaaaaagc tcctctctat tttatctgta gtaccgttcc tattcgttct
    19861 gatgccttat tatgttttct ataagagtgg aatttatctg ctctacaact agtgcataaa
    19921 tttaaattta ttatattttc ttttttaact ccactacatc taagcatata ctcattaatt
    19981 ttccataaat ctaaatagta acttccctct tttattatat agaacttttc atcattattt
    20041 gtaagaattg tgttaaattt ttctactaaa tcttcagaca cttcataaca acatggtcca
    20101 attgatggcc caattataca tactaaatct tcaggaactg ttttatagca ttcagacatt
    20161 aattttattg ttttatgacc tatattacta aaagtccctc tccaacctgc atgagccagt
    20221 cctatggctt tatttttagc atctataatt gatataggta cacagtctgc tgtaaacagt
    20281 aaaagtggta ctttttccaa gtttgttata agtgcatctc catctcttct tttccctata
    20341 gtatctttat tgactatatt aactatatct gaatgtattt gagaattact agttagattt
    20401 tcaaatgtca aatcacattc tttacatact tttaacatat cttctctatt ttttgcatct
    20461 atattcttac atgttataac tagatttaca gaatttaatt tttcatcaag ttcttcacaa
    20521 ttaccactta aattaacata ctctttaata tcttgtacat tttttatatt tatataatct
    20581 ttcatcattt gtctcctttt tctatcagta tacttttaag ttcatttaca aaagtattta
    20641 tatctttaaa ttgtctatac acagaagcaa atcttacata ggcaacctca tctaactctt
    20701 tcaatttatc cattaccatc tcaccgattt ttttggtttc aatttcttct ataaaacatt
    20761 tatttatttc attttcaata tgtacaacaa tactttcaat ctcgtcaata gaaacaggtc
    20821 ttttttcaca tgcttttagc aatccatatt ttatcttttc tctatcaaaa tattctctac
    20881 tattatcctt tttaatgacc attaaaggag ttgtttctat tttctcatac gtagtaaacc
    20941 tctttttaca tgattcacac tcacgtcttc ttctgataga ttttaaatct gtatgtctag
    21001 aatctattac ctttgattct ttataattac aataaggaca ttgcatctat attcctcctt
    21061 tgtttaacta tatctcaaac tcatctaagc ttaattctga acctatattt actattattg
    21121 tatcacaacc tattttaagt atatcattcc aaaatataac ttcttcatcc cctcctcttg
    21181 aaaaaaaact tctacttcca tctccaaaaa tggtaaatga gactacctta ccttcgtgaa
    21241 tatccatgtc tatgtctatt ataaacccca tcctttttcc attttttaca tttataattt
    21301 ctttttccat tatatcagaa actctaatca tattgtactc accctttctt taaaaataaa
    21361 tatgtatcga agtaaaaaaa aatgacctat ataggtcatt taaattaaaa taatgtttac
    21421 agtccatgga ttacttatac atattttctc atatttttta aagcattttt ttcaattctt
    21481 gatacttgtg cttgagatat accgatttca tcagcaactt ctatctgagt tcttcctttg
    21541 taaaacctta aatctaatac caacttttct ctactattta atttcttaat agcttcttta
    21601 agtgatattt cttgcaacca attttcatca gtatcttttt tatcttgaac ctgatccata
    21661 acgaatattg catctccatt gtcttgatat actgggtcaa acagagatat tgggtcttgt
    21721 atggcatcaa gtgccattac aactgattct acttctaatt ctaattcctt tgctatttct
    21781 gatactgtag gttctttaga atttgttcta attaatcttt ctctaacttg tagtgcctta
    21841 tatgctatat cttttaatga cctacttact ctaattgggt tattgtctct tagatacctt
    21901 ctaatttctc ctataatcat aggaacagca taagttgaaa accttacatt ttggcttaaa
    21961 tcaaagttat ctatagcttt tataagacca atacaaccta tttgaaataa atcgtctata
    22021 ttttctcctc tgttgttaaa cttttttatt acactcaaga ctaatcttaa attccctctt
    22081 acaaactgtt gtctggcttc ttcatcacca ttttttattt gtaataaaag ttccttcatt
    22141 tgcttatttt taagaactgg aagttctgat gtattaacac cacatatttc aaccttatta
    22201 acttgcatat attttcagtc ctctctcaaa agtattcatc tattgaaatt atttacattt
    22261 ccaatttttt tatacttttt aagaagaatt aatttagcat tatacaaatt ttttcatttc
    22321 tttttgcaac cttgagatta ttttcttttc aagtctagat atgtaggact gtgatattcc
    22381 aagcattcca gcaacttctt tttgtgtttt ttcaatacct ttatcaataa gaccaaatct
    22441 taattccata atttgctttt ctctgtcact taatctgtca agtgccataa ccaacaaatc
    22501 tctatctatt tcttcttcaa ttattttgta tatttcatca ttttctgtac ccaatacatc
    22561 agataataaa agttcgtttc catctaaatc tatatttaaa ggttcatcaa atgatacttc
    22621 tgttttcttt ttattatttt ttcttaagta cattaatatt tcattttcta tacatctcga
    22681 agcataagtt gccaatttta tatttttatt cagtttaaaa gtattaactg cttttatcaa
    22741 acctatagtt cctattgaaa tcaaatcttc tacatctata cctgtatttt caaattttct
    22801 cgatatgtag actactaatc taagatttct ttctattaaa attgacttta cactttcatc
    22861 tgtttctagc ttttgtaaaa gctccatttc ttcttctggt ttcaatggag gaggaagtat
    22921 atttgcccct cccatatagt atattccctt tggctttatt atttttaatt taatacctaa
    22981 catagtaata aagcttatta ttctttcttt caatcgtaac attccttgtc ccccttaaat
    23041 tttcacctaa aatccaggca atatatttgg attcattatt gctccatatt ctctatcatt
    23101 aaaatttgaa ataccaagta ttatatttcc tatcttttgc tcatctactt ctatatagtc
    23161 agcttttaag cctattatta tgcttgtctt attacttcca gcatgtttat aaggtattat
    23221 tctaactcta cctgaagttt tatcatctaa acttcctata atttcttgtg ctttcttcat
    23281 atctatatct tcataattaa tatttaatag tttttctgga ataaatcctt ctaacacact
    23341 agacttaact attattacat cactttgact tattgggtct tttaacaaat taccactatc
    23401 tactaaagcc ttacagcaaa aacttttttc tagtaagttt atatttatag tctttgtaag
    23461 ctccttaatg tacttaagca ttttcaaatc tttataaatg tattttaata attcacaact
    23521 cacataagta catgcaatta agaaagatat ttttaagtga cttattcctg taaaataaat
    23581 tataaaataa gtgcttccag aaataaaaat gtttactaga taaaaaacta acgctacatg
    23641 aacataatct tttttgctct tacttctaaa tgaaattaaa gttattatac tcatgattat
    23701 tattttaaat ggtacagtaa atagtatatt cattgatgga tacaaataag caacagaata
    23761 ggcacctcct aaactagccc ccaataactt atttttttta ggattatatc ttttagtaag
    23821 aatagaagta caacttataa taatataatt tattactagg ttttctataa catagtactc
    23881 aatatacacc atgtatcccc ccttaaaacc tttaaacata ttataagata gtatgtacaa
    23941 aattttatgt cacttttgat ggtcgaatcc aaaacaaatt ctatttaaaa agaacaatga
    24001 tatatgtctt atactttatg tcgtcaaaag atattttttt aataccaaac aaatagactt
    24061 ttttgtagaa tccaatatat ctaggtagaa gttattcact ctacttttgg tatatttaca
    24121 aaaaaagact acataattta ataatatatc aagtaaatct tttacttata taaaatcaaa
    24181 ttatatagtc tgtaaattca aatataaatt attgtgctag taatccattt gcatattttg
    24241 cagattcatt tagtgcttgt tctggagtta tgtctccagc tatcatcatt tgaagttgtt
    24301 tccataaata ttcatatatc tctactccat gaggtccaac tgtcaatggt ctatacatat
    24361 gtttatctct tgtcaccatt tcttcaaatc ttgggtctcc ttggtatttt tcacctttag
    24421 caactggagc tctaggtatt tctttgtgga aagcttccat tgattctttg cttagcatat
    24481 actcaagaag tttaaatcca agttctttat ttttacatgc tgacattaat gttaaatcat
    24541 ctactgaagc aaaacttcca actgtcttat cttctaatga tgttacatat ccccagttta
    24601 aatccgggaa tgatttatca aaagtacttg tagcagcaga ggatagcatt atagtaaatg
    24661 cagcttttcc tggtccaaat acactttcaa tcatttcatt actatctttt gataaagcat
    24721 cttctggaat atactttttc atatcattta taaagtttgc agctttcaag ccttctgcat
    24781 tattaaattt aactgatttt aaatcatcat tatatatatc tccaccagct tgccataaat
    24841 acggatacca gttccagttt aagcttccaa atactttaga accccaacct tgtgcaagac
    24901 cccactggtc gatttttcca tctccatcag tatcttttgt tgctttttca cagattcttt
    24961 taaaatcatc ccatgttttt ggaggttttt ctcctaattt ttctagtata tctttattgt
    25021 agtacaatac gcctggatta gcagcttcta taggtaaacc ataaatacca cccatcattt
    25081 ttgcatcatc taagtataga taattatctg aagttcctga tttttctaaa taaggtgtta
    25141 aatcttctac cgcacccatt tctataaatt gaggaaacat ctctgcatac atgtatccta
    25201 tatctggacc ttcacctgca cttattgctg ttgcatattt ttctgcgtag ttatcccatg
    25261 gtactatctg aaattcaatt tcacagttat tttctttttc aaatttttca aatatcggct
    25321 tccatgcatc tgcatcatgg tctgttaatg gtgcagacca tacaactaat ttttctttac
    25381 cctctttgcc tttagaatct tctttttttg aacatcctgc aagaattgat actgatagaa
    25441 tccctaccat aactaaagaa agaacctttt ttagtttaat catgcttaat cccctttcag
    25501 actttaattt gtctttttcc tcaaatgttt acatttaatt cagatttaat attaacaaat
    25561 aagattactc ttgtctaatc ataaaaaact atactaactc ctataactat attttttttc
    25621 tatacctatt agatttaatt catactaaaa acttactttt taaattttat caatatttaa
    25681 aaattttttt aagtctagcc acaaactaac tatctaaatt gagcaaaata aaaagaagtc
    25741 tattgacttc tttataagct tacatattat cttcttcttc ttaggaatgt aggtatctcc
    25801 atgctctcat catcatcttc ttcaattata cttgcctttt taggaggctc tattttttcc
    25861 tcagcaatta cttcttcttc aatttctttt acagcttgtt ttactgttgt atttaatgaa
    25921 gaacgtatgc ttgatttagg tttagtatct aaatctaagg caccattttg taatccttca
    25981 aatcctgtcg cgattactgt aatcattatt tcatcaccta aatcttcttt tatagaagct
    26041 ccaaatataa catttgcttc tgggtcacag gattccataa ctaaagttga tgcctcatta
    26101 acttcaaata atcctaagtt aggaccacct gtaacattaa gaagtactcc tttagctcct
    26161 tgtattgatg tttctagaag tggagattga atagcttgtc ttgcagcatc aattgctcta
    26221 gtttcaccac tagcactacc tatacccata tgagcaagtc ccttgtcttt cattatagta
    26281 gtaacatctg caaagtccaa gtttattaac ccttcaactg ctataaggtc tgaaattgat
    26341 tgtatacctt gttttaatac atcatctgca actgcaaaag catctaacat tgatgtattt
    26401 ttttgtacta tctgtaaaag tctatcattt ggtatcgtta taagagtatc tacttttgat
    26461 ttaagttctg ctattccacc ttcagcgttc ttcattctta tcttaccttc aaatgcaaaa
    26521 ggtttggtaa ctacacctac tgtaagtatc cccatttctt ttgccaagcc tgcaaccact
    26581 ggagcagctc ctgtaccagt accaccgccc attccggctg ttacaaagac catatcagct
    26641 ccttgaagta actttactat ttcatcttta ctctcctcag cagctctttt ccctacttct
    26701 ggatttgctc ctgctccaag tcctctagtt aatttttctc ctatttgaac tttatattca
    26761 gcttttgatg tatataaagc ttgtttatct gtatttactg atataaattc aacgcctttt
    26821 agttgagctt ctaccattct attgacagca ttgtttccac cgccacctac acctattact
    26881 ttaatttgtg cacattcttc taattctacg tcaaagttta gcatcataaa cccccttctc
    26941 tcatgattca aagttatcgt atgtattaat tatatcattt tcttctttta ttttgttaac
    27001 ctttaagtaa catattccac aaaaacgtaa attttccttt ttaaatttct tacttatatt
    27061 gtcaaatatt actctttaag tataaaataa tttacgtata tattaaatgc tctttaattt
    27121 ttacgttttt tgttcataat attactaata atatatcgtc taattataga taagttatta
    27181 aacaatctca taccaaaaac taatacagca acatagtaaa gagaaactcc taacttttct
    27241 cctatataag tcaataatat agccaatata gcattaccta tgaaaccagt aataaaaatt
    27301 acattatcat agttatcttc aaaattggat tttatcgctc caaaaataga atccattatt
    27361 gcaagaatag ctactgacat atatatggaa taatccatag aatatgtaaa tggaatatag
    27421 taacctacta ctacaccaaa tgctaatcct cctaaaaccc ataacataaa tcttcacctc
    27481 tttattttac tttgaaacac aactacatta caatcctttt tattaatttt ttttactttt
    27541 tctttatttt tttgtatttt tcgttttatt ttgcaaataa atccacttta tttccattat
    27601 tttcctgaac ttttatatta attccatata tatccttaag agatttagca tatgattctg
    27661 gagagtttat agctgcactc aataaatcta tatctcctat agcttttatt ataaatggtt
    27721 gtccatatgt agtatcattt actgtaatag tagctcctga acattttatc ttacttgttg
    27781 ctagtactct ttctccattt atagaaattg ctcttgctcc agcctttttt aaatcattta
    27841 aaaccctcaa aatatctata tcatgtataa tcaaatcgtt tggattctgt ccgtctttta
    27901 actctctctc actatccctc atagtaatag ttatgcctgg ccctgtaaca gttgaataac
    27961 cacttaattc tttaacttct tcaagctctt tttgcataag tgtttggata gattcatttc
    28021 cattcttttt tgcttcttta tattcattca aagttttttt gttgttttta agagtttctt
    28081 ttaaattttt tatttctttt tttgtatttt ctacctcact ttcaatactt tcagtttgac
    28141 ctaatgttat gtatactcta tttgggtcta gtgattttat ataagttgat atgaaaacgc
    28201 ctaatatgaa tgctcctaat ataactattt tctttttcat actattattt cccctctgct
    28261 ttgtttatat cactatgacc atttatttct atattgtctt ctttggtcac ttttactttg
    28321 gcattataat atgtttctat ttcccagaca ataccatact ttatattaag tgccgaagcc
    28381 aatgtatcag aatcaccaat tgcttttatt ataattggtt cttttatgac agtgtcattc
    28441 atataaagct tgtcttcttt taaatacata tatgtattag aaactattct ctggtcgttt
    28501 atagatatgg cacttgcttg tgctgaattt aatttattta tcattgacaa taataaatca
    28561 taattatata gtatactatc atttttatca gagtttccta agtcttttgt agaatttatc
    28621 tcaattttta tgcctgttcc ttcaacatct gtatatccag ctaatgtttc atatttttct
    28681 atttctgact taagtatgtc ttgttctcct tcattgtttt tgcctctata agtctctata
    28741 tctttcttca cactattaac ttctgattgt agattctctt tttctttttt taaagattta
    28801 agttcttctg taagttgctc tcctctttta aaagttgtca tccctctatt ttctatatta
    28861 ataattttaa gttgtaaact aacaagaaca cccaatacaa tacttcctat gattatactt
    28921 ttatttataa atcttttttt caatatatca cttccttaca attgtctatc cttctggact
    28981 atacactgcc aactttccat agttaagatt tatagtccct ccattagtat ttttattttg
    29041 caggtcaatc agaattttac ttaccctaga tatattataa tctaagttat catcattaga
    29101 aagtaagatt tttatattac ttcttgtaag catttctata ttgctttctt tttttaagtt
    29161 tacataattt atttttctat aaattccttc ttcttttaaa taatttaaag ttttaaatac
    29221 attctcctta gttttataat ttttaaattt tatagattta ttatcatcaa tgctataatc
    29281 tacatctact atcaagtctt ttttactttc attagaacct cttagttctt ccaataaatt
    29341 tcctttttta tctatataac aataattatc ttcatctttt aatactgcaa atatttcttt
    29401 ttcttttaaa cttataatta tcttattggg aagttttctt tttatttcca cattttctat
    29461 atatggattt tttataagtt tatttttcat atctttaaaa ttgtatgcaa aaatattttc
    29521 atttagattt acatttagtt ctttcattat atttgatttg gtcaccctct tatttccaat
    29581 tacatctatt ttctttacat caaataaatc actttttaca attatacata tacaaaaaga
    29641 taacataagt ataaaaacta aaactatcat gacattattc gtatttaact ttcttctttt
    29701 tttcaaatat aatcaacccc tttggttaat aaatacacct ttagagcttg tttttcctac
    29761 aaaaaaatta taatatttaa agtcaaattt ttgcatttta ttacataaca tccaaataag
    29821 gtattaaatt ttataaataa atcaatattt catcaaaata aacatagcat actacatact
    29881 atttatatat ttaaatctgt atacatacaa ataaacccct aatttataat aatttagaaa
    29941 atctaatata ttataaatta ggggtaaata tttacttatc ttttctttat tcctattacc
    30001 ttagcttgac cttctatact tggagtcgtt tcttttttta tttcttttac ttccttaata
    30061 actttttctt tttttgtttt tttagaagtt gacttttgtg ttgaattgta tactttcatt
    30121 atctcatcat atataaggtc tatggcttca ggcttaccta tagttttact tgcatttgcc
    30181 atatcaacca aaagttctct atctcctaaa agtttaaata ctgctgtatt taggctctct
    30241 ggagttagat ttttttctaa aatagcaatt cctgcccctt gtttttctat actcttggca
    30301 ttatactctt gatgattttc agcagtataa gctttaggta ttattataga tggctttcca
    30361 agagccgtta tctcagctaa tgaaattgct cctgcgctac ctataaccaa atcacttgct
    30421 gcaagtgcat ttgccatatc ttctaagtaa ggcacaactt tttggtatgg tttaagattt
    30481 atatcgctaa tacttcccat aaattcatca taatagcttt tgcctgtagc aaatataaaa
    30541 gctatatctt catttaccat attctttatt acaagtctca ttgcatcatt tatttttctt
    30601 gaacctccac taccaccata gcaaagtacc attctttttt cgtcacttat tgatagattc
    30661 tttcttgcaa tattttttct tgataataaa atttcttttc taactggatt tcctgtaaaa
    30721 actaatttat cttctgctgc ctctggaaat cttttatgcg aatcttcaaa acttgtaagt
    30781 acctttgtaa ctgttttaga taaaatctta ttagttacac caggaaaaga attttgctca
    30841 tgtattatgg ctggtatttt ccccatagat gcattaaata aaacaggtcc actaacatat
    30901 ccaccagttc ctataactat atctggttta aatttcttaa caatctttct tgattgctcc
    30961 aaacctttaa aaagcttaaa aactcttttt acattatcga aatctatttt tcgcttaaaa
    31021 ccttgaactg ttacagtctt taattcaaat ccatacttag gaactatttc tgactctatt
    31081 cccttttccg tcccaacaaa aattatctca gcgtctggat gctcatctct tattttgttt
    31141 gcaatagcta tagctggata cacgtgccct ccagttccac cgcctgataa taaaactttc
    31201 atcaaatcat catctcctgt taattaattt tgacatgctt tgagatgttt aacactattc
    31261 ctacagctcc cataaagatg gtgagtgaag ttcctccata acttataaat ggtagtgcta
    31321 cacctgtagc tggcattgat gatgtcgcaa ctgctatatt taaagctgct tgtattccaa
    31381 tttgtgcacc tatacctata acaaccatac aagcaaatac attagaagtc ttcaaagcta
    31441 ttcttacaca tctgtagact aaaactacaa atagcataat aactattata caaccaatca
    31501 atcctaactc ttctcctatt atagcaaata taaagtcatt ttgtggctct ggtatataaa
    31561 aatacttttg tttactcttt cctaagccta gaccaaacaa tccacctgaa cctagtgcat
    31621 atagaccttg tattacctga taccccttac caagagggtc ttgaaaaggg tctaaaaatg
    31681 atgtaacacg actaagtcta tagggttcag caattactaa tgcagcaaat aaagcagccc
    31741 cactccctat catagcaaat acaattttca tatccattcc agcaacaaat atcattacaa
    31801 aagtaactag aattacagta cctgctgttg acaaatttgg ctgaagtatt atcaacgcaa
    31861 aaaatatccc tggaactacg agaagtggta caacaccttt tgtcaaagat tttattttat
    31921 cataattttt ttcaattaat tttgcagtta atattattgt agcaaacttt gcgatttctg
    31981 caggttgaaa tgttaaagct cctattccca accatctttt tgctccgttt gcttctatcc
    32041 ctaaaggggt caaaactaac aataataata ctactgctat agctccaatt gctgtagcat
    32101 ttttcttcca aaaactataa tctattcttg atgtaataat cataactata aatccaagta
    32161 cagcatatat tacattcttt tttagaaaat agtacgcatc attgtgttta aatgaagatt
    32221 gtataaaact tgcactaaac accataacta ttcctacaaa tactaaaagc atagtagtgt
    32281 aaaacactac tccatcaaat tcagtcttca cccttatgtc aatttgtttt ttcaaatttt
    32341 ctttaggcat ccaactaatc tacctccatt cttccattta agtaagttta gaggtaagag
    32401 attattttaa attgtttaca ttatctttga agtcttttcc tcttacttca aaactttcat
    32461 acatatccca acttgcacaa gctggtgaaa gaagcactat atctccactt tttgaaattt
    32521 cataagaagt cttaactgct tcttccatat cttttactat atgtatgtca ttaaatcctt
    32581 tatttttagc acaattttct atatttgatg cagtttctcc taataagacc aatgatttaa
    32641 catatgactt tgcagtttca agaagttcat caaaattact tcccttatcc atcccccctg
    32701 ctataagtat tataggtcta tcataagact gtatagcttt tatagtggaa tctggattag
    32761 ttccctttga atcatttaca tatattacat tgtctaaatt tcttacaaac tcttgtctgt
    32821 gttccactcc tttaaatgtc ataagtacat cctttataac ttctaaatca attttgcaga
    32881 catatgctat tgctatagct gccatacaat tttctaagtt atgacctcca ggtaaactta
    32941 catcatcttt atttagaaat ttgattttat catctatatc tattattatg tcattatttt
    33001 ctaaatatac tcctccattt acttttttag ttcttgaaaa gtaaattact ttggcattgc
    33061 atttatcagc taaagatttt actatctcat catcatagtt taatacacag aaatcctcaa
    33121 cagtttggtt cataaatata tttgcctttg cttctatgta tttttccata gtatggtgtc
    33181 tatttaaatg gtcctctgta atatttaata ttgcgcttac tttaggtcta aattcatcta
    33241 tactctcaag ctgaaaactg cttagttcag ttactaacac agactcttca cttgaagttt
    33301 ctatagtatc tattacagga tttcctatat taccaactac atatgtatct cgttttgctc
    33361 ttgaaaaaat ttctcctacc aaactagttg tagttgtctt tccatttgta cctgtaatcc
    33421 ctataaaaat tggattatcc gatagtttaa aagctaattc tacctcacca attatatact
    33481 tgcctgaatt ttttaatttc aatatgaatg gtaggtctag tggtacacct ggagacacta
    33541 caaccatatc tatatcatct acatcttctg ggtgatgtcc taatatgtat tttatgtcat
    33601 ttatagattt caattcatca agtatatttc tcaatttatt ttcatctttt atatcattta
    33661 cgattatact tgcacccaat ttatctaaat gtttaattgt agatatacca gtttttgcaa
    33721 gtcctactaa taaaactttt tttcctttta agtccatttt tcattccccc tagccctaaa
    33781 atactgctat tatacttatc caagctaaaa caactgttat aatccaaaaa ataaatacaa
    33841 ctcttgtttc tggccaacca cactgttcaa agtggtggtg tattggagcc atcttaaaga
    33901 atctctttct tgttgcctta aaatatccaa cttgaatcaa aactgataga gcctccgcaa
    33961 aataaattcc tccaattata ggtattataa gcactgagtt agttagaact gaaaatgcta
    34021 caactgcacc tcctaatgcc attgaacctg tgtcgcccat aaacactcta gccggatatg
    34081 aattaaatcc taagaaacct aaacatgctc caacagttgc tgctgctaaa actgcgactt
    34141 ctgtatttcc agcaatagaa cttgcaaata gcataaagaa tacagaaact attaatgtta
    34201 ctcctgatgc taatccatct aatccatcag tcaagtttac agcatttact attgctacga
    34261 ttataaacat cattattggt atatataata ttccaacatt tatcacaaaa tctgtaaatg
    34321 gtatcataag ttgtgaagca cttgatgatg atgtatactg ataaaaagca acataaaaag
    34381 ataatgcaac ttgaaggatt attttttgat atgcttttag tccaagtgat ctttttagct
    34441 ttatttttat aaaatcatct aaaaagccaa taaaaccaaa acctgcaata catataagac
    34501 ctactgccat atcatgacta acttttactc ttgtaagtcc agttattaga attgcaacaa
    34561 tcattataat tccacccata gtaggtgttc cgtttttagc tagatgtgtt tggggtccat
    34621 catctctaac tgtctgacca aatttaaatt ttctaagcat tggtataaat attggtccta
    34681 ttataattac tattaaaaac gcaatcaatg cggtgtacgt aagctctgtt attcctaaca
    34741 tcataaaact cctctccctt gtcaattaac tcattagttt aagcttattt atttagatat
    34801 tcgactattt tttctaatct catgcctctt gagcctttta ctaaaatagt gtctcctgtt
    34861 tttactaatt catttaactt gttaaacaca tcttctctat tctcaaagtg atatatattg
    34921 gctgaattga atcctaattg ttttgcttct tctccaataa acactgaatt ttcacctata
    34981 gttattataa tatcagtatt attcatagat gattttccaa ctaatctatg accatactct
    35041 gaaatttcac ccatttctag tatatctcca agtatcgcta cccttctacc tttatatctt
    35101 ccaagtatct ttaaagcagc atccatagaa tctggactag cattatatga atcattaatt
    35161 attgttaatt tttcattttt tattatgtct agtctcattt ttgtcccttt aaaatttttt
    35221 aaaccttttt ttatataatc taaagaaata tttagacaca aaccaactaa tatagcagac
    35281 attgcattat atatattatg ttctcctatt gttggtataa atatttcctc ttttttccca
    35341 tctattacac atataaatgt taaactatcc tcttccatag tataactttc acaataaaca
    35401 tcattgtttt tattaaagcc aaatgttttt aacttatata catgttcttt ttcttttaat
    35461 gtagataaaa acttatcatc tccatttaca attaaagtat ttgtttcatc aaagtttgaa
    35521 gtaatctcca tctttgcttt caaaataccc tcttgtgaac ctagtttttc tacatgtgat
    35581 aatcctatat tcgatatgac tgcaatttta ggatttacta tatccactaa atattttatt
    35641 tcattgaatc cagacatacc catctctatt acagcacact catgttcttt atttagatta
    35701 aataaagtca atggaactcc aaaatgatta tttaagtttt tttcattttt tagtatattt
    35761 aactttgcag atatggcaga gtaaatcata tctctagtag tagtttttcc cacactacct
    35821 gtaacaccta taaatggaat atcaaatttt tctttatagt attttgaaat atctcctaga
    35881 gccaaagatg tatcttttac ctctattaaa tttatatccg aactttctaa ttttattcca
    35941 ttactttcat tttttataaa agttttacat ccactatcat atgcagactt cataaatgta
    36001 tgcccatcta aattttctcc aactatggct acaaatgcat tttgggcatt tgcctccctg
    36061 ctatctataa ctatatcact tacacagtca ttataatctc catatattaa cttcccatta
    36121 gttgcaagta ctaactcttt tattgttaag cactccatta ttaaactcct cctttaaaac
    36181 cttagctata ttctcttagc aacaaaaggc aatgtatacc gttatatata cattgcctac
    36241 gataactctt aactttataa ttatatacta tatttctgtt tttttgaaga tgtttatggg
    36301 tatatgttaa ttatctgtta ctttttagtt ttcaaaatat agggttatac ttgagtcttc
    36361 attaactttt actccaggtt ttgggaatat atcctttacc tttgtatctt ctggaagttc
    36421 tatatctgca tctaagtctg gttttaactt cgcatcctcc aatgccttta cagcatctcc
    36481 tatttttaga tttcttacat ctggcacttt aacttgcttc ttttcatact cagctttttc
    36541 ttcttcttta tatactggtt taactcccaa atattttaaa gagtcattca ttatttcttt
    36601 cactattggt cctgctgtag tactaccaaa tgcacttact cctgttggtt cgtcaacaat
    36661 agcaagaact actatttgcg ggtcatcaca aggtgctatt ccaacaaatg aacatatata
    36721 ctttcctgga gcatacttac catctataac tttttgagct gtacctgttt taccaccaag
    36781 tctataacct ggtatatacg ctatctttcc tccaccttca gttacaactg attctgcaat
    36841 ttctaacatt tttttagatg tttctttaga tataacactt cttacttttt ttggttttac
    36901 tgtttcagtt atatttcctt tattgtcagt ataagatttt accactcttg gttgcattaa
    36961 atctccacca ttagctattg atgatatagc tgttataagt tgtattggag ttactgatat
    37021 agattgacca aatgatattg tagccaattc aactggtcct acattttttt cgttatacag
    37081 tattccctta gcttctcctg gtaaatctat acctgtctta tccataagac caaatgattc
    37141 tatataatca tacatttttc caacacctaa tctgcttcct aactcaacaa atactgggtt
    37201 gcaagagttt tgtactgctt gtttaaattc ttgtgttcca tgaggtctgt aatgtctcca
    37261 acatttaatc tttcttcctc caacagttac actacctgta catgtgaatt tttctccatc
    37321 tttaattact ccttcttcaa gagcactgga agatgtaata agcttaaatg tagaacctgg
    37381 ttcatatgta tcacttactg ctggatttct ccacatttga taatagcctt ttattttatc
    37441 tttatcatta tatttttcaa gttcttcttg ataatatgga tatattggcg tccttgagtc
    37501 attagggtca taatctggtt ttgatgctaa agcaagtata tcacctgttt tagggttcat
    37561 agctattgca gtaacctttt ttgcattatt taactcataa gctttctgta ctgctttttc
    37621 agtatagtgt tgaattactt catctataga caacacaaga ccattacctt gtacaggctc
    37681 ataatatttt tccattcctt gtggtatttc tcttcctgaa gcatcagtac ttactataag
    37741 ttttccaggc tttcctttta actttttatc atattgcatt tctacaccag atatacctgt
    37801 tgcatctgaa gaagtatgtc ctaacacata tggtgcaaaa ttcccatatg ggtaatatct
    37861 ttgattatct tctgccaccc atattccact taatttagca tctcttattt gacttgcctt
    37921 atcatcatct atccatcttt ttacttttac aagagccata ttttttttgc ttattaaagc
    37981 gtaaatatct ttataatctt catccaaaat ctcagctacc ttttcggctg cttctttttt
    38041 atcttctact tccacaggtt tacaccaaac agtatactta gttacactta ctgctaactc
    38101 tttcatattt ctatcatata tagttcctct tttgggttct attggtatat ctcttgtttg
    38161 ttgttctagt gcttttgtac tcaaccaatt tcccttcata agttgtagat acccagtcct
    38221 aataacaagg caaaaaaaca atgcacatgc tagaataaga acgagtacca gccttttctt
    38281 acttatcctc tttacttttc tcaaatctat tccccctagt tatccacatc tatatacttt
    38341 atttgtccat cttttggata gtccatattg agcaattcct tagcctttag ctcaatttct
    38401 tttattgatg ttttttcagt ttcttttgcc tttagttcct ctaatactat ctcttttttt
    38461 cttaaatctt tttgtaaata atagatatcg tacttcattt ccgagatttt tgaataacca
    38521 catagattca atattattac tgaaaaagtt gcaatcagta aaatgcattt agctcctatt
    38581 tttttcttat ttctcttttt ataattattc ttttttttat ttttatattc atttagatta
    38641 tgtattttat aatttttttt caaattctca ccccgatagt atatagttta aattttcctc
    38701 tatactatat ttgttattaa tcatatttct tcctctaaaa tttcatcgct aaattaatac
    38761 actattacac aatctaattg tatttttttc tatacacaac aaaaacctat aaattcactt
    38821 atacttttat atgaatctat aggttagata ttaatttcta tttattttta tcacttctag
    38881 tatttttaga taatttcttc cataaatata atatgtaact aactatctac tctctgattc
    38941 ctaagttctc cattatatta cttaatacca tctatatcta tatttttata tctaaatttt
    39001 cattatatat ctcaataaca aagaacattt cttatagtgt taattgtttt ttaattgctt
    39061 taccagtgca acaaaatata taatactttt taattaatta taataatctt atatataaga
    39121 ttattcttta gccttataac tacttatatt ttttctgcta ctcttagctt agcacttctt
    39181 gaacgtggat ttacttctat ttcttcctca ctaggtaata taggttttct agttattatt
    39241 ttcacctcag attctttatc acattggcat ataggtaaat gctgtggaca tatacaatct
    39301 gatgctaaat gcttaaatgc atttttcact attctatctt ctaatgaatg gaatgttatt
    39361 atacatattc ttccaccttc attcattata gaagaagcat catttatcat ctttgtaatt
    39421 actccaagtt cattatttac ttctattcgt attgcctgaa aagttctttt agctgggtga
    39481 ggtccatcta ttctggcttt cttagggata gcttttttaa ttacatctac taattctcct
    39541 gtagtttcta ttggtttgtt tgctctttct tcaactataa atttagctat acgcttagcc
    39601 cagttatctt ctccataatc ttttattatc ttagttaatt catcttctgt ataagtattt
    39661 acaacatcat atgcagaaaa ctcacaccta acatccattc tcatatcaag tggtgcatct
    39721 tgcatataag aaaatcctct atcagcttca tcaagttgat gagatgaaac tcctaaatca
    39781 gctaatacac catcaatttt gtaaactcct attttttcta attcctcttt tatattttca
    39841 aaattgctgt gaacaaactt cactctactt tcatattcac tcaatctctc ttttgctgtg
    39901 cttatagcat ttttatcttg gtcaaaccct ataaataatc ccttatctga cagttttttt
    39961 actatttctt tagaatgtcc tgctcctccc atagtacagt caacatacac gccatctggc
    40021 tttatattta aattctctat acactcattt aaaagaactg atacatgatg aaattccata
    40081 gttacctccc ttaaattcac tttttaaact attcttcact aatattattt ttatttttct
    40141 ttgataaata aacatgtgca attatgccac caataactcc aattagactt ataacttgtg
    40201 ccattctaag tggtcctaac attaaactat ctgttcttaa tccctctata aaaaatcttc
    40261 ctattgaata taaagttata taagtaacta taacttgacc ttcatatttt ttattttttc
    40321 taaatagtaa taaaactata aatattccaa aatcccatat agactcatat aaaaaagttg
    40381 gatgtacctt tactccatca accattattc cccaaggtaa attggtagca cctccatgtg
    40441 cttctccatt aataaaattt ccccatcttc caatagcttg tgctaaaggc attccaagta
    40501 taactgtatc agccattttt aagaagttaa tatttttaat cttagtgtat atataaccag
    40561 ctaatattcc accaattaac cctccatgta tagcaagtcc accacctcta aaattaaaaa
    40621 tttgagacat attttgagca tagtaactcc aattaaatac aacataatag attcttgcac
    40681 agattagtcc aactggaatt gctattatag ctatatttaa tacatcatct tctttaattc
    40741 ccactctttt tgcttctttt attgctatta aagttcctaa aatcattcca catgccataa
    40801 gtattccata ccacatgatg tctatgccaa acagtgtaaa tgctactcta tccataacgt
    40861 cacctctttg tattaattga aaatatttcc aaagcaatat gctataatta caattaattg
    40921 taattatact aaattatgat aacacattaa tgttaattct acaaaaaata ttaaaattta
    40981 ttctacaact ccctacacta tattatatct aattactata aaatttttta aactaaatct
    41041 ctcatgacta aagttacaag tgtacataga tattttttaa tcaaaaagat tgatgcatat
    41101 atacatcaac ctcttctaat tcttatctat agctcttaaa tttttacctc aatttatata
    41161 aatatatttt ataaatttgt tttaccaaaa taaacattta aaaacataaa ctaatactta
    41221 attagttatt cttattatga ttaagtttct atttaggctc tacaatagaa ataacacaat
    41281 actcttcttt aaaatgctct tttaatcttt cttcaacttc ctcaaaagta atatctttaa
    41341 taatatctaa ataatccaat agatttatat ccttaaaaac ataagatata aaactattac
    41401 ctataaagtt tatagaatca aagcacttaa taaatgaccc tatttttttc tttttagttc
    41461 tctcaaactc ttcttttgat aatccttctt tttttgattt ttctatataa tcaagaatta
    41521 tttcttttac ttttttaggc tctttagaat ctccagctat tatgctaaaa gcataatcca
    41581 cttgagacga aaatccagct ccaaaatttt catttattaa accttgcata tacaaatctt
    41641 cataaagctt acttcctttt ttaaataaca tccctacaag tatatcagtt acaatctctt
    41701 tacgtaaaag ttctttccct tttaaaccaa cattgctatc tttaaaacct atgttgaaca
    41761 taggcataga tatagggaat ttttctataa cctctttttc ttttacactt tctggttctt
    41821 ctggataaaa tctttctata ctcttagaga gtctgtctac tttgtaattg tttgactttt
    41881 tagttacatc tataactttt tctacatcta agtcaccaac aacaaataaa gccatatttc
    41941 ctggattata gaaagtatta taacatttat atagctcttc cttagttatc ttatatatac
    42001 tatcaacagt acctgctata tcaattctag caggataatt tacatacatt gccttcaagc
    42061 aattaaagta tacattccaa tcagggtcat cattgtacat ttttatctct tgtgctatta
    42121 tacctttttc cttttcaaca ttttcatctg taaaataagg tgtttgaaca tagtcaatta
    42181 gatgttctaa actctcataa aaattttcag tagcagaaaa taagtaggct gtcattgtaa
    42241 aattagtaaa tgcatttgca tttactccta attttgaaaa tttatcaaat gcatctcctc
    42301 catcaggttg ctcaaacatc ttatgctcta gaaaatgtgc aataccttca ttcactctaa
    42361 ttttcttatc ttctccaatt ggtacaaatt ctaagtcatt tgaaccataa ttagtagcca
    42421 aaatagcata ctttttcata aaaccccttt taggcataaa atatacatct aatccatttt
    42481 gcaatttctc ataataaact tcttctttca atatatcatt aactattttt tccatagaca
    42541 tctcctccat taatttctca agaagtatac agtatcaagc tctatatttt ttatagcttc
    42601 aactatatct ttttttgtaa ccttttctat actagatatt atgtcttgta cttcagaatt
    42661 tgtctttgcc atagactgag agaaaacaaa atcagacata ccacctatat tatcagttat
    42721 agatttcata gaattaacta aagcaagttt actgttttct aattcttcat cagatatatc
    42781 acctgctttt acactttcta cttgtttttt tatcaattct acagctttat cataatcttt
    42841 agtttctata ccagatgata taaacatgat acttttatac ttctctattg aagagaatat
    42901 atagtaacat aaactttctt tttctcttac attaacaaat aatttagagt gtggaccacc
    42961 acctaagaca ttgctcccaa ctactaaagc ataatattta tctatgtctg cataatccac
    43021 atttgctcta taacccataa ctaacttacc ttgagttatt tccatttgtt catctataac
    43081 ttttacctca tccacatttt ttataaaatc tgctcttggt atatttataa tttcttctct
    43141 ttcaaatttt agatttttac ttattatatc tacaacttta tcttcatcaa aattaccttc
    43201 tacaactata tctataggtg atgttttaag tatgttttta taatgttcat ataactctct
    43261 tgaagttata ctatctattt catcttcata accaaattca cttacactat atctctctcc
    43321 tttacacata gcctcaatac atttatcttg cgcatattcc tttttatcat ttattattga
    43381 ttgtatcttt tctcttaaat tctctttttc aatatttaaa tattcttctt taaacccacc
    43441 atctacaaca agcgtattat ttattacttc attaaaaaat tctactactt cttcaaatat
    43501 actctcatct aaatactttt cacttatgtt aattacttta aaactcaata cttgacgttc
    43561 tccacgtttt acagcatcag ctcccataga tgaaccatat aaatcatcta atttattgga
    43621 tattgctcta gcactaggat atttagcgct tccacttgct attattgatg gtattagagc
    43681 attttttgta gtttcttttt catccaatag tctctgaaca tataaactta taagattcga
    43741 tttaaacttt tctgttttta tcaaagtaag attaatatta ttacctaaat ttattatttt
    43801 tttagtatta accatatgta cctcctattt ttatttaaac atcaatttta aaattgaaat
    43861 ttatttattt tttaattaca tatactcaca tataaaaacc ttctatttaa ttatatcctt
    43921 tttattattt tctaaaagca atatttttat ttaaattaaa tacaaatatt atttaaatca
    43981 atatgcttta aagtctagtt tacaagcttg atatatatga tgtataatca atatgtatgt
    44041 ctataattaa aacaattttg caatcctata gattgattgt ttaaagttat ataaagaata
    44101 taaaaaagaa taagagagag gacgattaat atgaaattag gtatagttgg tttaccaaat
    44161 gtaggtaaaa gcacactatt taacgcaata actcaagcag gtgcagaatc tgcaaattac
    44221 cctttttgta caatagaccc aaatgtggga gttgtatctg ttccagatga aagattaaac
    44281 aaactacaag aattatataa ttctgaaaaa atagttccta ctgctataga attttgtgat
    44341 atagcaggtt tagttagagg agcttctaaa ggagaaggtt taggaaataa attcttatca
    44401 catataagag aagttgatgc aatagttcat gttgttagat gttttgagga tgaaaatgtt
    44461 gtacatgtag atggttctgt agacccactt cgtgatatag aaactataaa cttagaatta
    44521 attttctcag atatagagat tcttgaaaga agaattaata aaactcaaaa agctgctaag
    44581 gctgataaaa ctttaggttc tgaacttgat ttattaaaat caataatgtc tactttagaa
    44641 gaaagtaaat gtgtaagaac tatggaattt acagaagatg aacaaacatt cgtaaattca
    44701 ttggatttac ttacatctaa gcctgtaata tatgcttcaa atgtatcaga agatgattta
    44761 gctgataatg gagaaaataa taaatatgtt caacaagtta aagcatttgc agaaacagaa
    44821 gatgccgaag ttgttgtagt atgtgcacaa atagaagcag aaatttctga acttgattct
    44881 gctgaagaaa agaaagagtt tttagaaaca ttaggtcttg aacaatcagg gcttgataag
    44941 cttataaaat cttcttatgc tttacttggt ttaatttcat tcttaactgc tggtccaaaa
    45001 gaagttagag catggactat aaaagttgga agtaaagctc ctcaggcagg aggaaaaata
    45061 cattctgata tagaaagagg atttatcaga gcagaaacaa tagcctttaa tgatttggtt
    45121 gagcatggta ctatggctgc tgctaaagaa aaagggttgg ttaaattaga aggtaaagaa
    45181 tacatagtta aagatggaga tgtaatatta tttagattta atgtttaaaa tgattaatcg
    45241 tatacacttt gactattata tataataact aaaaaactaa gattataata atacaatatt
    45301 atcttataat aattatatag aatttaaaaa taaaagaaga gtatttcaaa tgatttgtat
    45361 aaattattat gaaaaactct ttttttgata taataaaatt acttacatat ataatattta
    45421 aatttataaa ttatattttt attttttaaa atatgtataa cacacctata gaaattacta
    45481 ttattactat ctaaagtatt ttgctataat cccatatact cttacctcaa aaacattcaa
    45541 atgtaaaaaa tactacatat taataaactt tgcccaataa ttcctaaaat aatatcctaa
    45601 caatgattta tgtttttata atagtatatt tttacataaa aaagtgaaca ttgattaaca
    45661 aagttcactt ttttataaat ttttatgtta taattcacaa ttttatttaa tttgtttctt
    45721 ttctatttaa actatatcta tctaatatta atttttcata ttcttctatt ggcattggtc
    45781 tagcaaataa aaatccttgg gccatatcac aacctataaa ccttaaaaac tctgcttgct
    45841 ctacagtttc aacaccttct gaaacaactt ttatatcaag ttgctttgcc atttgaacaa
    45901 tacttgaaac tacaatttga ctcttttttg catttcccac tgttataaag aattgcctat
    45961 ctaatttcaa tacatcaatt ggcatatctt taagcatatt taaagaagaa taaccagaac
    46021 caaaatcatc catagaaatt ttaaatccaa cagatttcaa agtttgcatt attttaaata
    46081 atatttttgt attgtcaaat attgcacttt ctgtcaattc aatctcaatt aaatttggtt
    46141 caatttcata ttcttttgtt attctttcaa gctcagaaat aaagcctgga ttctcaagat
    46201 gtactcttga taagtttatt gatataggaa atgtggggaa attttcattt tcccaacgtt
    46261 taaaattttt acaaacttgg gtaaatacaa acatatccaa ttctgttata aaaccatttt
    46321 tctcaaaaat aggaataaat acacctggac ttattagacc ttttttggga tgttgccaac
    46381 gtacaagtgc ttcagcacct acaattttag tagttgataa atcaacctta ggctgtaaat
    46441 aaactttaaa ttgttcattt tttaaagcat catgcatttc ttgttcaata tcacgttctt
    46501 ctatgagagt ttcttttaaa ttttcagcat aaatctcata aacttttaaa tattttcttt
    46561 ttactgtagt ttttgcaatc atagctttgt caagacaggt agaaatattt gtttctccct
    46621 cttcaacaaa atatacacct atggatggaa ttaaattgag ttctactccc aaacttgttt
    46681 ttatcattga caatttttta cgtataagtt cacatatttc tataattgac tctctattat
    46741 ttttcttttc aaatattata gcaaaattgt catttgaaat tcttgaaaat acagattgct
    46801 ctttaaatat attcttaatt atctctgcta tttcctttaa tactctatct ccttcttcat
    46861 acccaaacct atcatttact agcttaaact tatctatatc aaaataaatt aaaactagat
    46921 tctttttctc atgagaggat aaaaattttc ccccttcaag attaaattta tttgaattgc
    46981 caatacctgt aacgttatct ttaaaagcaa attcttccaa tttttcctta ctctttttat
    47041 gtataaatag tatataaatt gttaatgccg taaagattat aatcaagact acacatgctg
    47101 ataatgtaag ttttataata gcatatgatt tctcagatat agcagtttta ggaacttcag
    47161 aaaaaagata ccaatcattg attcctattg gggcataact taaataatat ccttttccaa
    47221 acatactata acttaatgaa cctgatttaa agttttttat atttgacttc atattgttga
    47281 tactagattt tgatattgaa tcacttctgc caatgtaaga aaataaattt tctttagtag
    47341 agttggcgtt tttactgctt ggatttaaaa caatatcacc attacttcta gttatataag
    47401 aatatccttt tccattaaat gtaggtacag aaagtatttt ttcatacaac ttcgtactat
    47461 gtgtggcaaa tataactcct ttaacctcat tatctttata aattggtaca gaatatacat
    47521 taatattact attggtattt ttatcatctt ctattacatc ttttaatttt cctgttataa
    47581 ccacttctcc ttgcattgat tttaagaaat aatctctttt agagaagtct tctatataac
    47641 catctgtagt gtatgctgta ccatttggta aaataactcc cattctttta aatgaactat
    47701 taatagcttg tctttttagt atagaaagga tattatctac ttcaaaagac tcttctcctt
    47761 caataaatat tgaaattgac tctagtaact ttatatctcc attaatttgt ttttttaaca
    47821 cattgacgct ttgatttgct atttctgaaa gatattgatt cgtttcttca cctaatgtct
    47881 tattcaacct tgaaccataa atcaaacagg aaattgtaat tactaagata cttatgacag
    47941 caattatgga caaaccatac ctattatttt ttgcatcact taacattatg cttcctgcct
    48001 ttctcgaatc tatgtatgta taatcattat cttatgacaa ttattgtaaa cattttataa
    48061 taatacttat ttttccatat ttactgtaat tatacaaaat tataaacttt attacaacaa
    48121 taaattaatt aatatagata ttagtgttta cattattgca ttatctattt tacaattatt
    48181 tacatataaa aaaatgtaat atcaaagtga agcttgatat tacatttttg ttcttgtatt
    48241 ttgtttaatt tttatgctac atcttactta aacactcatt tgcaacttct ttatcatcaa
    48301 aatgatgctt aactttacct ataatttgat aagtttcatg tcccttacct gttataatta
    48361 caacatcatc cttttttgcc atacttatag cttctgctat agcttgttct ctatcaacaa
    48421 caacatggta attttctttt ttcttgtcaa ttccttcaag tatatctttt attattgcct
    48481 ctggttcttc agttcttgga ttatcagaag ttataataca taaatcagaa tatttttgtc
    48541 caattgctcc catcaaaggt ctcttttcag tatctctatc tccaccacac ccaaacacag
    48601 aaattatttt tccttctgca aattgttgag ttgtctttag tacattttca agtgcgtcag
    48661 gagtatgagc atagtctaca attacgctta tacctttatc atttggaact gtttcaaacc
    48721 ttcctgatac tccattagaa agtctaaggc cttctttata tattggttta ggtatgccaa
    48781 gtacatagca agcagctata actgctaaag tattatatac tgtaaacatc cctggaactg
    48841 gtataaatat tacttcttca tatgaaggtg ttattaatct ataagatact ccatccgaat
    48901 ctgattttat atctctagcc ataaaatcag ccttagtatc aacaccataa gtgtaacaag
    48961 gtacatttat accttttata ttttcatata tcttttttcc accttcatca tctatgttta
    49021 ttatatttgc catagtagtc ttaaaaaata atttttcttt tgcttttcta taatcctcta
    49081 aatctttatg aaaatctaaa tggtctggtg ttaaatttgt aaatatgcct agtttaaagt
    49141 ctgtttcatc aactctattt aatgccaatg aatgtgatga aacttccatt gcacagtagt
    49201 cacatccatt atccaacata ttattaaaat gatattgtaa atctatactt tctggagttg
    49261 ttgaattgga aacaatgtct ttttctccat caaaaatttt tatagttcct ataagtccaa
    49321 ctttattctt atttaaagtt aatatctcat ttagtatagt agttatacta gtttttccat
    49381 tagtacctgt aactcctata acgttaaatt tttgagatgg atgattgtaa aaattatcag
    49441 ctacttttgc catatctttt cttgtatctt ttacctttat aaatgtacat ccttttattg
    49501 ctacatcttc ttcaacaaga aatgcacttg ctcccttttc tatggcatct tttatatact
    49561 tatgaccatc tgacacaaat ccttttatac atataaataa tgtacctttt gtaacctttc
    49621 ttgaatcata ttgtacatta ttaatatcta tatttaattc acccttgaca ttgattatat
    49681 ccaacccctg tataatatca tttaatttca taaatgcttt cctcccttta aactctttct
    49741 gctaaaatta cactacatat aatattatat taagaatttt ttactatgtg aatggttaaa
    49801 aatgcttgaa acattgcaaa aaatgctcta taattttcta taatataact gaggaaaggt
    49861 cttctataaa aactatggat aataaaatcg ggtacttaaa cgataacttt aaaatattta
    49921 atattagaga taaaaaagat atacaatttg aataccataa tcatgatttt aataagataa
    49981 ttatatttat aaatggaaat gtaacttatt ttgttgatgg tattccctat aaactaaagc
    50041 cttgggatat actctttatc agcaataatg aaatccataa accagttata gattcaaatg
    50101 tcttttatga gagaattgca atatggatta gcccagaatt tatgaaaaaa aatagtgatg
    50161 ctagtagtga cttagaaaaa tgttttaaaa tagctacaga gaataaatgc aatagattgc
    50221 gtttaaatat gcatgatatt gaatctatta agagttttat tgagcaaata aatatttccg
    50281 aatccaatac tgaatttgga aatgaaatat tgagaaatac attatttata caacttatga
    50341 tattcttaaa cagaattttc ctaaaaaatg aaaatatgga atcaacagaa gatgtttttt
    50401 atgatgaaac tattaagaaa gtattaaact atataaattc aaatatagat gataagcttt
    50461 caatagatag catatcgtct gaatttttta taagtaagta ttatcttatg agaaaattta
    50521 aatctcatac tggaacgtct atacacaatt atatagttca aaaaagatta attttggcaa
    50581 agtcactaat aaccaatggt caccttatga gtgaagtttg taataaatgt ggattcaacg
    50641 attattctag ttttgtaagg gcatttaaaa aaaactacgg tgtatctcct aaaaattata
    50701 taaacaataa aaatccttta gatattactc ttttagatga atagataatt tatgtaaatt
    50761 ttattttaat aaaacttgaa gtattagtgt atttatctta ctaatacctc aagtttttta
    50821 atgttttaaa atatatcaaa atataatgat atatatttct attacttaaa atatatatta
    50881 aataaattgc atgttaactg aacctattta tatatttatt aaatctcaca taacttttag
    50941 ttacactatc atatagctat cctatttttt caatatcatc tcttaatata cttactctat
    51001 tctcctcttt tgctgtggtt actccttttt taatgcttaa tttctgattt tgttctaaat
    51061 tcgtaaatac tacaggactt attgttgata gaccattttt ttcaatatat tctaagtcca
    51121 ttttaactaa tttttctccc gcttttactt catctcctac attcacaaat acttcaaatc
    51181 catttccttc taagtttaca gtttctatcc ctaaatgtat aagtatttct actccacttt
    51241 tttgggattt tattattatt gcatgcttag ttggaaatat aactccaata gttccatcaa
    51301 ctggtgaata aatcaatcca tcactagatt taattgcaaa tccatccccc atcagtttac
    51361 ttgaaaatac agaatctggc acttcttcta tatctaataa ctctccattt gttaatgaat
    51421 caatcttttc tactaaagta ttttccatat ttgcaacttc catatttttt ttcactttat
    51481 ttttatcaac atttttagta acagtacttt caacctttgt ttttccctct attatatctt
    51541 ttatatcaga ctttattgaa tctgattttg gtccaaatat agcttgaaca ttgttgccaa
    51601 taaccataac acctgctgct ccaagtgatt tcaatttttc tttatctact ttatttatat
    51661 catttacaac caatctaagt cttgttatac acgcatctag actctttaag ttgtctttat
    51721 ttcctaaagc aatcaaaatc tctgatgcta attcattctt agacatttca atgacttcag
    51781 cgttagtttc tgactcatct tctcttcctg gtgtctttaa attaaatttt cttatcataa
    51841 atctaaatac actatagtat aatactgcaa aaccaatacc taccaagata gccaagtacc
    51901 atggagttct attaggaaga acaccaaata ataagaaatc tattaatcct cctgaaaatg
    51961 tgaatccaat tttaactcct aataattgca taattgcgta tgataaacct gaaaataaac
    52021 aatgtattgc aaataatact ggtgcaacaa ataaaaacgc aaactctatt ggctcggtta
    52081 ttcctgttaa aaaagaggtt aatgctgctg atgccattat acctgctaca aattttttct
    52141 tttctggctt tgcttcatgc accatagcaa gagctgctgc tggaagacca aacatcataa
    52201 atggaaatgc acctgtcata aaagtacctg ctgtgaaatt tactccatct ttaagttgag
    52261 caaagaatat cttttggtca cccattacaa gctcaccagc tttatttaca tattctccaa
    52321 attgatacca aaatggatta tggaaaacat gatgcaaacc aaatggtatt aatagtcttt
    52381 ccaaagaacc ttccataaat gctgctagtg tttgatttgc ttctataaca ttttttgaga
    52441 aactaagtaa tccctcttgt attggaggcc aaataaaaga caatataatt cctattgcta
    52501 tagcaactaa tgaagtaacg attggtacaa atcttttacc tgcaaaaaaa cctagatact
    52561 gaggtaattc aattttataa aactttttat aaagataagc agccactatc cctataataa
    52621 taccaccaaa tacccctgtt tgaattgttg gtattccaac aatatttgca tacatagaat
    52681 tgtctaccat atcttctgta acacctgcca taacacccat agatgtattg agaattaaaa
    52741 aacctactat ggctgccaat gctgcaacac cttctccttc agttaaacca acagctaccc
    52801 caactgcaaa tataagtggt aagttattaa atataatttg acctgaactt tccattatac
    52861 ttattataag ttgaaatgta ggattcgcca aagctggaaa atgagccaac aatgcgtctc
    52921 ctgctaaagc attactcacg ccaagtaata tacctgctgc aggaagtaat gcaactggta
    52981 gcattagaga ttttcctact ttttgtaaaa caccaaatac ttttttcatt tacttttctc
    53041 tccttattat tttatatttt tttaaataaa aaagacttaa gtttataaaa agttacatta
    53101 gtatacttaa ttctaaaatt aaacttatgt taatataaac aaacctatat taacctaatt
    53161 tcagaattaa aaataaacta ttataatttt tttataaaca taagtcttgc ctgcattatc
    53221 agtaacaatc ttaatgtttt aaaattatta tt
//
LOCUS       DAEHWO010000019        50807 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEHWO010000019 DAEHWO010000000
VERSION     DAEHWO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.019"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            266..1792
                     /locus_tag="KNP54_001388"
     CDS             266..1792
                     /locus_tag="KNP54_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBF0892294.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            1820..2377
                     /locus_tag="KNP54_001389"
     CDS             1820..2377
                     /locus_tag="KNP54_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892295.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            2899..3936
                     /locus_tag="KNP54_001390"
     CDS             2899..3936
                     /locus_tag="KNP54_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892296.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNQILTKVVNDDNEIEEKIIEEDLLISENTIKLDDKEAIINDKNIELCKKEVQVE
                     SEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAINL
                     YTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKSEW
                     SYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYDEY
                     FKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTKVG
                     RNFIRYSLRSI"
     gene            4047..5189
                     /locus_tag="KNP54_001391"
     CDS             4047..5189
                     /locus_tag="KNP54_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBF0892297.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            5643..7034
                     /locus_tag="KNP54_001392"
     CDS             5643..7034
                     /locus_tag="KNP54_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBF0892298.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            7287..9080
                     /locus_tag="KNP54_001393"
     CDS             7287..9080
                     /locus_tag="KNP54_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBF0892299.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIAPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(9161..10543)
                     /locus_tag="KNP54_001394"
     CDS             complement(9161..10543)
                     /locus_tag="KNP54_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBF0892300.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            10801..11148
                     /locus_tag="KNP54_001395"
     CDS             10801..11148
                     /locus_tag="KNP54_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBF0892301.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            11166..12200
                     /locus_tag="KNP54_001396"
     CDS             11166..12200
                     /locus_tag="KNP54_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892302.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(12249..13298)
                     /locus_tag="KNP54_001397"
     CDS             complement(12249..13298)
                     /locus_tag="KNP54_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0892303.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            13573..15108
                     /locus_tag="KNP54_001398"
     CDS             13573..15108
                     /locus_tag="KNP54_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892304.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(15293..15979)
                     /locus_tag="KNP54_001399"
     CDS             complement(15293..15979)
                     /locus_tag="KNP54_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBF0892305.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            16104..17486
                     /locus_tag="KNP54_001400"
     CDS             16104..17486
                     /locus_tag="KNP54_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBF0892306.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            17888..19156
                     /gene="eam"
                     /locus_tag="KNP54_001401"
     CDS             17888..19156
                     /gene="eam"
                     /locus_tag="KNP54_001401"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBF0892307.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDTCDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(19249..19605)
                     /locus_tag="KNP54_001402"
     CDS             complement(19249..19605)
                     /locus_tag="KNP54_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892308.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(19756..20850)
                     /locus_tag="KNP54_001403"
     CDS             complement(19756..20850)
                     /locus_tag="KNP54_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBF0892309.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            21314..22135
                     /locus_tag="KNP54_001404"
     CDS             21314..22135
                     /locus_tag="KNP54_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBF0892310.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            22156..23352
                     /locus_tag="KNP54_001405"
     CDS             22156..23352
                     /locus_tag="KNP54_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBF0892311.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSISYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            23519..26917
                     /locus_tag="KNP54_001406"
     CDS             23519..26917
                     /locus_tag="KNP54_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBF0892312.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            26927..28600
                     /locus_tag="KNP54_001407"
     CDS             26927..28600
                     /locus_tag="KNP54_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBF0892313.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLEPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            28873..29067
                     /locus_tag="KNP54_001408"
     CDS             28873..29067
                     /locus_tag="KNP54_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBF0892314.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    29236..29469
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            29546..30943
                     /gene="asnS"
                     /locus_tag="KNP54_001409"
     CDS             29546..30943
                     /gene="asnS"
                     /locus_tag="KNP54_001409"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBF0892315.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(31116..32291)
                     /locus_tag="KNP54_001410"
     CDS             complement(31116..32291)
                     /locus_tag="KNP54_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0892316.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            32710..34074
                     /locus_tag="KNP54_001411"
     CDS             32710..34074
                     /locus_tag="KNP54_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBF0892317.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            34096..34587
                     /locus_tag="KNP54_001412"
     CDS             34096..34587
                     /locus_tag="KNP54_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBF0892318.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            34860..35531
                     /locus_tag="KNP54_001413"
     CDS             34860..35531
                     /locus_tag="KNP54_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBF0892319.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            35616..36482
                     /locus_tag="KNP54_001414"
     CDS             35616..36482
                     /locus_tag="KNP54_001414"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBF0892320.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            36515..38017
                     /locus_tag="KNP54_001415"
     CDS             36515..38017
                     /locus_tag="KNP54_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBF0892321.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            38147..38599
                     /locus_tag="KNP54_001416"
     CDS             38147..38599
                     /locus_tag="KNP54_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBF0892322.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            38759..39562
                     /locus_tag="KNP54_001417"
     CDS             38759..39562
                     /locus_tag="KNP54_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892323.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            39620..40507
                     /locus_tag="KNP54_001418"
     CDS             39620..40507
                     /locus_tag="KNP54_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBF0892324.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGKDATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            40526..41374
                     /locus_tag="KNP54_001419"
     CDS             40526..41374
                     /locus_tag="KNP54_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0892325.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            41437..42126
                     /locus_tag="KNP54_001420"
     CDS             41437..42126
                     /locus_tag="KNP54_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBF0892326.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            42517..43524
                     /gene="asrA"
                     /locus_tag="KNP54_001421"
     CDS             42517..43524
                     /gene="asrA"
                     /locus_tag="KNP54_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBF0892327.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            43525..44316
                     /gene="asrB"
                     /locus_tag="KNP54_001422"
     CDS             43525..44316
                     /gene="asrB"
                     /locus_tag="KNP54_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBF0892328.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            44329..45300
                     /gene="asrC"
                     /locus_tag="KNP54_001423"
     CDS             44329..45300
                     /gene="asrC"
                     /locus_tag="KNP54_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBF0892329.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            45357..46133
                     /locus_tag="KNP54_001424"
     CDS             45357..46133
                     /locus_tag="KNP54_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBF0892330.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLIDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     NTVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            46404..48422
                     /locus_tag="KNP54_001425"
     CDS             46404..48422
                     /locus_tag="KNP54_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBF0892331.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIINTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            48637..49494
                     /locus_tag="KNP54_001426"
     CDS             48637..49494
                     /locus_tag="KNP54_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0892332.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            49591..50460
                     /locus_tag="KNP54_001427"
     CDS             49591..50460
                     /locus_tag="KNP54_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0892333.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
BASE COUNT        20176 a         5377 c         8762 g        16492 t
ORIGIN      
        1 ataaaattta agcagaagaa taaatttcta acgaaattgg atatttcttc tgtaaataca
       61 tattcaaaaa aagaattata agagtttagt cagcagtcgt gtaagtaata aggactttat
      121 aaatatatag aaatataatg atattaatat aaccaagcga tttttaattt agctttttaa
      181 taagcttatt ttttatacta tttataataa ataaactcca tgatgggaaa actattacta
      241 tttaatatgt aaaggagtat tttaaatgaa tgaatcatat tggtttttaa actcaagtcc
      301 aaaagaatat aacaaattag gtgaaaatat aaaaacagat tgtcttatag taggtggtgg
      361 aataacggga ttgacaactg catatttatt agcaaaagaa ggtaaaaaag tagtgcttgt
      421 tgaggctgat aaaataggat atggaacttc tggaaggaat actggtaagg taacttgtca
      481 gcatgatata ttttactcta agatagagaa aaaatatgga ttagataaag caaaatcata
      541 ttataatgca aataatgaag ctttaaattt agttgaacaa ataatagaag aaaacaatat
      601 aaaatgtgat tttaaaaggg aaacttcttt tgtatttaca gaaaaagagg atactataaa
      661 ggatattaaa gatgaatatc gtacatgtaa aaaaatagga ataaattgtg agtatcatga
      721 aactatagaa aatattccat tagatataaa gggggctatt agttttacta atcaaggtca
      781 atttaaccca aagaagtata ttgatggatt ggcaaaagca gcagtaaatt tagggctaaa
      841 aatatatgaa aatacaccag tagtagacct tgaaaaagga aaaatatgta gggttaaaac
      901 aagagaggat aatataatag aagctgagaa tgttataatt tcatctcata gtccatggta
      961 tgatggattg aatttttatt ttgcaaaaga atatgcagag cgtgcttatt taatggttgc
     1021 agttttggaa aataaattag cagatggtat gtttataagt atagatgacc catcaataac
     1081 ttttagacaa tataatgatg gaagtgaaaa tttactgatt tttggaggag gagaccataa
     1141 agttggtcag ggaggaactg agaaagaaat atttgatgat ttagagcatt atggtaaaga
     1201 agtctttaag gtaaaagatt ttaaggggaa atggtctgct caagataata tgagttttga
     1261 caatgttcct tatattggtt atatcaacaa aagagaagac aatatttatg tagctacagg
     1321 gttctctaaa tggggaatta ctaatggaac tgctgctgga ataataataa aagatttaat
     1381 aataaataat aattctgatt ataaagatac ttttaatcca tccagactag gtagctactt
     1441 ttcaaaagat tttataaagg aaaatgcaaa cgtagcaata aattatgtaa gtggaaaatt
     1501 aaaaataggt agtggagata tgcctaaaaa taatggagaa ggaaagattg ttaatattga
     1561 tggaaaaaga tatggtgtat ataaggatga taatggagat ttttatattg tagacactac
     1621 atgtactcat ttaggatgtg aacttaattt taacagtgaa gaaaaaacat gggactgtcc
     1681 atgtcatggt tctagatttg actataaggg aaatatactt gaaggaccag ctcttaagcc
     1741 attaaaactt tatggacatg gtgataatga tgttaatcct aagttattat aaaattattt
     1801 ttaggaaggt aaagtgtata tgaataaact tttaaagcca ataactatac tattgtatat
     1861 agtttatatt ttatctgccg tattttttgt agcaaacaaa gaatatggaa gtctaggtct
     1921 agtagcaatt agtttagttg gtactttcat tttgagtttt ataaataagc aaactgaaag
     1981 attattgagt aaagaattat atataatgct tgctttattt ataatgtttt catcattgtt
     2041 aggtacttgt tttaattttt atgatataaa ttattatgat gattttttgc atttatggtc
     2101 aggtataata tcttgtattg tggctttttc tataattaaa tacttttata cacaaagaga
     2161 gataagtaaa atgagtaaag tgtttttagt tatattttta tttatgttta gtatgggagt
     2221 agcgagttta tgggaaatag gtgaattttt aatggatact tttgttggga ctactacaca
     2281 ggccggaggg ttagaagata ctatgattga tatggtagat gctttaatag gcacaattat
     2341 aactattcct tttatagtaa aaaaatctaa tatatagttt taaatttttt atattaatta
     2401 taatggattt aattaatcat gttgagtttc aaggtctata tgattaatta aatccatttt
     2461 tgttatttat aattattatt gaatatattt ttacatataa gatataaggt gatagataga
     2521 aattgttgga ttatgtaaat aattaatata taataccatt atgggcaata aatacaaatc
     2581 aaatgataat atagtctatt tatgtaaatg ttatattgta tcctaagtat aatagtaagt
     2641 tttttgatag tggtgtagaa agtaaaaatc tactagccta aattgatgta tggattagtt
     2701 taggaacagt aattgcatat cttaagtttg atgtcatgtt gggctactag aaataggtca
     2761 tctttttcac ttgaatatct tttctttaaa catggggagt atcatatcaa aaacatatga
     2821 aaattaagtg atttatgaga acagtaatat tttatatgat agtatagaat agtaataaag
     2881 tattaggagg aacattgagt gttaaaaaag tggtttggta ttgtgaaaaa aagacaaaaa
     2941 agtgagtcag taaaagaaga aggtgaagta atattaaaaa acgaaaaaat attatctgaa
     3001 gaaaagttga tagatgaaga aggagttgta gttaatattg ataatcaaat attaactaaa
     3061 gtagtaaatg atgacaatga aatagaagaa aaaataatag aagaagattt gttaattagt
     3121 gaaaatacca taaaattaga tgataaagaa gcaattatta atgataaaaa catagaatta
     3181 tgtaaaaaag aagttcaagt tgaaagtgaa aaaataggtt taaataagtt tgaaggactg
     3241 gaccaaaatg aaaattataa tctagaaaaa aatgttattg aagaaaaaaa agtaagtgaa
     3301 tgtttgacag aagaagattt agagtacata aaagaaatta aaataaaaag aggaaaaagt
     3361 ataaaagcta taaacttgta tactaaagaa gagtgggttt ttgacactca tatacagtgt
     3421 agtaaaaaac tcaaagttcc attagggtac ataagagaaa atttaaaata tggatatatg
     3481 gattactttg gagatgcaat aaattattta agtgaagtat taaatataga tgaatactgc
     3541 aaaagtgaat ggagctatct cgataatagc aaatctccat ctgagatatt taatattcta
     3601 aacaataaaa tatttagtat aaggctttct aatgaaaaaa gaaatgaaat tttgacaaat
     3661 gataaaattg aagcattaaa aatgaattat agatttgaat gtattgatga agaatatgat
     3721 gaatatttta aaaaatataa gtctataatc aaaagaggtg gaaagaaaaa agttgaatta
     3781 gtaaataaaa aaggtgacat tttagaaata tttaagtctt tagaagaatg tgccatttat
     3841 ttgcaaaagg aaaagaatga agttatacaa atgttaaaat atggagatac aaaagtagga
     3901 agaaacttta taaggtatag tttgagaagt atttaatttc attttaaatt cataagagtt
     3961 tcatttctga ttcacacatt taatattatt ttaatgtaaa ataataaagg tgaagtattg
     4021 cacaattaaa attaaggagg gtattaatgt ctgaagaaaa aaatccaaaa gaaaatacat
     4081 tagatgaatc taaaaattca gataatgtaa attctaaaaa agatgatgtg tcagatgaaa
     4141 aaaatactga taacaaagtt aaaaaaaggg aaataaagct aaacaacaaa acacttaaag
     4201 ctattgtagc aattgttgca gtaggagcta tatgtttagg tggaggctat gtttttggca
     4261 aagaagctgg aagaaaattg cctgctactt caaaacacta taatagcagt gaggtagtag
     4321 ctactattgg ggataaaaaa ataacaggtg aaatgttaag aaagagaatg gagccattat
     4381 tttatttaaa tgcaaaaact actatgactg atgacgaaat acgttcatat gaatcaaata
     4441 tgattgaaac tatgattaca tctgatatat tatcctctga agcagcaaaa gagaaaataa
     4501 gtataactaa tgaccaacta gatgctcagt ataataattt aatgagtagt atagaatcag
     4561 caatgggaat gactaaagaa gagtttttaa aacagtttga tttgactgaa aaatatataa
     4621 aagatgatat gaaaaaagag ctagtagcat caaaatattt aaatgaaaaa tcaaaagtta
     4681 ctgataaaga agcagagaac tattacaata aaaacaagag caattattta caagttagag
     4741 cttcacatat tttaataaaa actgttgatg ataaaggtaa gcaagttagt agtagcaaaa
     4801 aagctgaact taagaaagaa gctgaagaaa tacttaaaaa agcccaagct ggggaagatt
     4861 ttgctactct agctaaaaaa tactctgaag atagtagtgc agaatcaggt ggagatttag
     4921 gtttctttgg taaaggtcag atggtggaat cttttgaaaa agcagccttt gcattgaaga
     4981 agggagaggt atctaacaaa cttgtagaaa gtgattatgg atatcatata attaagaaaa
     5041 ctgatgaaaa atatcagcca tttgaagagg taaaatcaga tttagtaagc agtttaacat
     5101 cagaaaaaca aaacctactt atacaaaatc taaaagaaaa atataatgtt aaaattacag
     5161 ataaatatca aatgaaagct aaagaataga taaagtcaat ttattaaaaa aaagaaaaat
     5221 taactgtatg gataaaagct atttttactc tcaatataga gagtataaaa tagcttttat
     5281 tattttgcaa taaaatctat ttatatatat gaagtgataa agaaataaca tgcaaaaagg
     5341 tattaaaaag aaatattttt aatttgaatt ttttcaataa aaatttacaa aaatgaaaaa
     5401 ataaacaaaa aagaattgaa gatttaagtt gttatttaaa tatatatata ttaagatttt
     5461 ctgctgaaga tactaaaaaa ataatatttt tcataatttt aaaaataata ataaaaaaat
     5521 gaaaatacag gctataatct attgagtaaa catagaaaag atgatattat aagtatgtgc
     5581 taaaatggtt aaagcaatat taatattaaa tttaactata aaacaaaagg gggcgttttt
     5641 ttatgtcaag tacagaaagc gtatctaaaa aaagtggtca tccgaagagt ttttggctta
     5701 tttgcatgac aattttgtgg gaaagattta gttattatgg tttaacagct ttattggtat
     5761 tattttttac agcaagtgta gctcaaggtg gtttaggtct ttctactcaa gaagcaacat
     5821 ctatgtttgg cttatttaca ggtcttatat atcttacacc attagtcggt ggctggttag
     5881 cagataaagt tttaggtcaa caaaaatgta tttctatagg tgcactttta atagcaatag
     5941 gagatttcgt actatttgct tcatctacat ctattgcaat ggtttgggta ggtctatcaa
     6001 taattatttt aggaaatggt ttttttaaat caagttgctc aaatatagtt ggggatatat
     6061 atcctaaaac tgatgtgtca agaaaagatg cagcatacag tttattctat atggcagtaa
     6121 atgtaggagc atttatagct ccaataatat gtggattgct ttctgataat gtatttgcag
     6181 taagaggagc aagtggagat atagtatctt atggatataa gatggcattt ttaatttgtg
     6241 gtataggcat gatgttaggt atgattatat ttacacttct tgcaccaaaa ttattaaatg
     6301 aagtcggaaa atatcctgtg actaaaggta ataaaggtga aaaaattgag tatggaccac
     6361 ttactaagtt ggagaaaaat aggataatag caatggttat tttattttta tttgtggtct
     6421 tattctggac agcatactat caaacacaaa gttcttttat gatttatgta agggataatg
     6481 taaatagaac tctatttgga tttgaaatgc cagtagcatg gcttacatca ctaaatgcta
     6541 tattatgtgt ggctttatgc ccagtattag ctaccctatg ggttaaatta tctcatacca
     6601 aaagaggtga tttctctatt ccagttaaaa tgggattagg aatgataata atgggtgttg
     6661 ggtttatagt tatggtattt gctacattag ctaatggtcc agatggaatg gtaaaggcta
     6721 gtatattgtt tatagtattg acttatatat ttacaacagt aggtgaatta ttcttatctc
     6781 ctataggact tgcaatgttc aataaattag ctccagctaa gtatgctacg ttgtctatgg
     6841 gagcctggta tctaacaagt ttttttgcaa gtttattatc aggaaagatt gctggtttta
     6901 cagccacact tggtttttta cagatatttg gaggaatagc aacagtttta ataatatttg
     6961 gtttaatatt attgggaata agaaatgtat taacaagatt aatggctatg gatttactaa
     7021 caaaagaaaa ataattcatg acgaattatt gtaaataaat gaattacttt aaataaagga
     7081 agttacattt aaatataaaa ttaaatgtaa tttcctcttt gattatgaaa aaaagcttta
     7141 cacaaataga tattataatt aaaattataa ttgtgataat tagagtgtat aagatttata
     7201 taaattatac aaaaaatatt tatgtaataa actttacata cttatatatt tagttattca
     7261 aactattatt tcgaggaggt cttgttgtga atataaaaga tagattaagt ggattaagaa
     7321 aatttatgga agaaaaaaat atagatgcct atatgattcc atcttctgat aatcaccaaa
     7381 gtgaatatgt aggagattac ttcaaatcaa gagaatttat atcagggttt aatggttcag
     7441 cagggacggt tattgtgact aaagacgaag ctgggttatg gacagatgga agatatttta
     7501 tacaggcaga atctcaatta gaaggaagta caataaaatt attcaaaatg ggacaagaag
     7561 gttgcccaac tacagatgaa tatttatata aaaatattcc tgaaggagga actttaggat
     7621 ttgatggtag agttatatct gctagagaag gagctacatt agctgaaaaa ttatctaaaa
     7681 aaggtataaa gatagaatat cagtatgatt taatagatag tatatggcca gatagacctg
     7741 ctttatcaga tagtaaagca tttttattag atgttaaata ttgtggagaa agttttagct
     7801 caaaattagc tagattaaga gaaaaaatga gtgaaaaagg tacttctact catgtaataa
     7861 ctactcttga tgatatagca tggttattca atataagagg tggagatgtt aaatataatc
     7921 cagttgtact ttcttatgca gtaataactt taaaagaagt ttatctattt gttgatgaaa
     7981 gtaagttaaa tgaagaaata ctaaatgaac tagctaagga aaatgttcaa ataaagccat
     8041 ataatgatgt gtatgaattt gtaaaaaata tagacaaaac tgaaaaagtt ttattagatg
     8101 gaactaagct tagttataca atttacaata atataccttg tgaagttgag aaagttgatg
     8161 agttcaatcc agtaatgttt tttaaagctc aaaaaaatga ggtagaatta gaaaatataa
     8221 gaaattcaca tgtaaaagat ggtgtagctt tcactaaatt tatgtactgg ttaaagaaaa
     8281 atgtaggtaa gatggaaatc actgaaataa gtgctactca aaaattagag gacttaagaa
     8341 gagagcaaga aggtttcttt gagccaagtt tcaatacaat tgctgcatat aaagagcatg
     8401 ctgcaatgat gcactatagt gcaactccag agtcaaatta taaattagag gcagaaggat
     8461 tatttttagt agattcaggt ggacaatatt atgatggaac tactgatata actaggacta
     8521 cagttttagg acctataagt gatgaattaa aactacactt tacttctgta gcaagaggaa
     8581 tgataaatct ttctaaggct aagttcttgc atggttgtag aggatataac ttagacatac
     8641 tatctagaag ttgcatgtgg aatatgggaa ttgattatca atgtggaact ggacatggta
     8701 taggatttgt gctaaatgtt cacgaagctc caaatggatt tagatggaga gtagtacctg
     8761 aaagatttga tagtgcagtt cttgaagaag gaatggtaac tactaatgaa ccaggtatat
     8821 atatagaagg ttctcatggt ataagaacag agaatgaaat tgtagttaga aaagctgaaa
     8881 agaatttcta tggtcaattt atggaatttg aagttgttac gttagctcct attgacttag
     8941 atggtatagc accagaatta atgaataagg atgaaaaaga ttatttaaat tggtatcata
     9001 agttagttta tgataaaata tcacctttct taactgatga agaaagagaa tggttaaaag
     9061 tttacactag agctatatag tttgtactag atacaataaa aatcgaggta ttataatgcc
     9121 tcgatttttt attgtatatt ttattaactt taaaaaattt ttaatttgat aattctacta
     9181 attttttatt cattataagt agtataattc caaatatcaa taaaaatgat ggtatcacta
     9241 tgaagacttg taacatacca agttggtcta taatagcttg cgtatagcca gataatttat
     9301 ttgctgcaaa tttgcctaaa aaccaaacac ccattaggaa tgaaatatac ttttcaggcg
     9361 aaagtttatt taccatacca tacccgactg gagaaaagca aatttctcct atactttgga
     9421 atgttaaaaa tccaactacc caaaatacac ttgctttgtg aattgaatta gggtctgttc
     9481 ctgtttgtat aactgctact atcataaaca aaaatgctat ggctaatagt ataaaaccta
     9541 agctcatttt ttttggcaca cttaaatcgc cttttttagt ttgagataat tttacccata
     9601 ctaaagcaga gataggtcca agaataacac aaaggagacc attgtatgaa tctatccatg
     9661 aagtaggaat ttgaaaattg ccaacagtaa gatttatgtg ttcctttgta tagagtgcaa
     9721 tagacataga ggcttggtta tatgctatcc aaaaaaatac tgtgaaaaaa gctaacacca
     9781 atattactat tattcttttt ttctcaatca aagttaaagg tcttgaagcg agcattttct
     9841 tatattctag tgattttctt atagactctc tcccgttaat agggtcatta ttcaaaggtt
     9901 tataaaactt tctgtttcca aatataaaga agaataaacc tattagaacc gtaattgatg
     9961 aaaataaaaa tacatatcta tatccataca tacttataga taatccgctt ttcatagcaa
    10021 accattcatt agcaactaaa ccgcatatta aagggccaaa taaagtacct agattagtag
    10081 ccatatacgt aatagagaaa gctccatctt ttcttgggtc atcattggta tataagtttc
    10141 caaccatagt atgtaagttt cctttataaa aacctattcc taatccagat aaaaatatca
    10201 tgatgtttat atccatctta ctatttgcta tgtatcctag aaaataacca attgaaacca
    10261 ttagcattcc aagtataata cagtttttgg gacctaaaaa tctatcactg acccatccac
    10321 caataactgg agagaaataa gtccatgcta aaaaagatgc aagcattgat gcggattctg
    10381 ctggtgttaa ccctaaacca cctttggaga cttgttcagc taaaaacaat aataatacca
    10441 atttcatacc atagtatgca agtcctacaa aggtaaatat tgaacagcag aaatataaat
    10501 ctctaggttg tttaagtttt tcttgcgttt ttaaaactga catatgtcga gaacctccag
    10561 ataaatagtt taacaaaatt ttaccatact atatgagtat atgttttttt catatagacg
    10621 tcaacttgta agataattta attaagtcga aatatatgta aaaatagtat catttttgtg
    10681 tattcagtaa tattttttta tgataatata tgttattatt atattaaaat acaaacatat
    10741 ttatggaaag gatatgccaa tttagtagtt agattgattg tttggcaggt gggatgagct
    10801 atgataagaa agaaatctga attacaagta gaagtaaaag aaaatttaaa tggtggtata
    10861 ggaaaggtta agcttgaaaa cataatacaa aatgaagagc ttaaaggaaa aggaagacta
    10921 tttaaaagag tagctttacc agtaggaagt tcaattggtg tgcatgacca tacaacagat
    10981 tttgaagtat attatatact aaagggaaaa ggtaaagtat ttgataatgg ggaatttgta
    11041 gaagtaaatg agggtgatgt agtgtataca gctgatggcg aaaaacattc tatagaaaat
    11101 ataggagaag aagatcttga gtttgtagca ctagttttat atatgtaaaa tatggaggag
    11161 gagtcatgac aggcaagata gaagaaatta aggacaagat aaatagattt tgcaactcca
    11221 atttaaatca agaatacaaa gatataagct ttaaaatttt gcaaaacctt ttagataata
    11281 ataaagagat aattcattct tctagagctg atatatggtc ttcagctata ctaaatatag
    11341 ttttagaaca aaatctttta tacaataaga agcatccact acatataaca aaaaaagagt
    11401 tttcaaaaca aataggtgtt tctttaaata ctataaataa taaatcgtct ttaataaaag
    11461 atgtttgtag tattgacttt ttaaatcaag atactatagc tatttctaat gtagaatttt
    11521 gggtaaaaga gactaattcc aaatcaaagt ctgtagattt agatttagaa aagaagaaaa
    11581 tactatataa aagatatatt aagctatcac aagatgcgaa tagtgatatt gaatcaatta
    11641 gatatatgga ggaagctgta aatataggta aaagtatgat tactaaagaa gataaagaac
    11701 ttggattttg gaaaggttta tctaccagag cctatatgat agcacttgaa tcccttgcta
    11761 gaaagttaga aagtattaat aatctaaagg agtccaaaaa agtattagaa tatttaatag
    11821 aaattaatcc tagtgatgag cagggaataa gatacaaatt attaaatgta ttaattagat
    11881 taaatgatag aacttcaata aataaattat ttgaacttta taaagaagaa aaatctgcta
    11941 catggatgta cagtaaagct ctttattact ttaaaaataa aagtatgttt ttggcaaatg
    12001 attctattaa ggttgctaga agtaaaaata agtacgttgg attatatttg ttagattggc
    12061 gaaatgcttt tggtagagaa tttgttacag aggaagaaaa ggcagaagct gtctattact
    12121 atgatgaaaa catagtgatt tggaatgaag ttaaaggttc tatggattgg ctattaaaaa
    12181 aaatgttgga attttcataa aaaaaactac tccttacttt tatataagtc aaaggagtag
    12241 tttttaattt atacatctag ttttaaatct tcaggtttta ttagaccttt ttttctcata
    12301 aattctgaaa tcaacaaagt tacaatagca ggaagtataa aattaagtaa aagtatacca
    12361 acccacatag atatacctcc ttttccagca ctttgcatag cagttactgt tccaaattgt
    12421 ccaaccaatc cacaagtacc cataccagaa ccaataggaa tattctccat tttgaatatt
    12481 gttgtagata atggtccaag taatattgaa gctacagtag gtggtatcca aattttccaa
    12541 ttttttatta tattaggtac ttgcaacata gatgtcccaa gaccttgtgc cacaaggcca
    12601 ccaactccat tttctctaaa gctcataaca gcaaagccta ccatttggca acaacaacct
    12661 acagttgctg caccaccagc aagaccacct aaacttaaca tcatacaaat agctgcacta
    12721 cttataggta atgtaagagc tattccaaca agtgcagaga ctaaagctcc cattattata
    12781 ggttgcatag ttgtagcttg cattattata tttccaaatg aagtcataaa agcagaaaca
    12841 gctggaccaa taagttcagc tacaagtact ccaattagta ttgttacagc aggtgtaacc
    12901 aatatatcta tttttgtttc ttttgaaact aattttccaa cctctacagc aaaaagtgta
    12961 gcgacaaatg ctccaacagg tcctcctaat tcattaccac aagctccaac aagtgcacaa
    13021 gaaaatagta caagtggagg tgcttgaagt ccatacgcaa tagccactgc tatagctgga
    13081 ccagtaacct gtttagcaag agggcttata acttcagtaa aaagagaaat attgaaatta
    13141 tctcctaatg tattgaaaat tgttccaatt aaaagggacg aaaaaagacc gagtgccata
    13201 taacttagtg cgtcaataag atacctttga acagaaattt caatattttt tcttttagca
    13261 aatgatttga aatttctttt tttataattg atttccaatt taaaatcctc ctcatataat
    13321 ataagtataa tttcttttta attaattata taacttttca gctgacaaga caaatgttat
    13381 ttcactaaaa ttagactatt gtaatagtaa gaaattaaca ttaattttag ttttaaattt
    13441 taaatttatg gtttataatt agtataggga tattctgaaa tataataatt ttccagttta
    13501 tcccaatatt taacttaggt agattgctta caaaacaaat gattatatat taggctaaaa
    13561 ggaagtggat agatgatatt tgtaaaaaat aagaaataca gaaaaattgc cataattata
    13621 tctattccta tattgcttgt tgcgcagtac taccttttta aatttggaat acttagacca
    13681 atggtaaagg gagtagaaat tgaaattgta gatggggaat atgttaaaga tatagataaa
    13741 tatgtagtaa aattaaatga aacagttact ttgtctacag gtgaatatat taaggttcct
    13801 tcgtatgcta aaaatccaaa tatttggttt aatgtattgg ataactcagg gactttaaaa
    13861 atagatggaa ataaaatgac agcattaaag gttgggtatt cttctgtggg tatcatgaaa
    13921 aattcaagag tattaaaaaa ggctactata aaagtagtag acccagaggt agaatcacta
    13981 gatatggaga ttaatgggga tttaaaacat gttggtgata gtgctactat agaaagtaca
    14041 atagaagttg attatgataa gtttaaaaaa tcatataagc cagtttataa gagtagcaat
    14101 gaaaatattt taaaaatcaa aggaaataaa gtaagtgcag ttggagttgg taaagctaca
    14161 atatatgcta agtgtggaaa taaagaaatt gagagaacat ttaggattca agctagagtt
    14221 gctgaaataa atatggatga tataaaaata gaagttgacc agaatgaaaa attgaaacca
    14281 gatataataa cttctccgcc tggtttagaa ccaccaaaaa tatattatga gttagtagat
    14341 tcaaaattac ctgtagaaag agcaataagt ttaagtagta atggaaatgt tgtagggctt
    14401 agagaaggta aagatagggt gagaataact tgtggagata aatctaaagt aataacagta
    14461 acagtagtca aagaaactat aacgaatgac tatatacaaa acttggttgg ttcacataaa
    14521 atagtaaaca ataaagttat tattaaactt gaatgggatt atatgaaaga tgtctttgat
    14581 tatgatatat atcttaaaga taagttgtca ggagaatcat ttaagaaaat taaatctata
    14641 actataaatg aaagtgattt aggtaagtct aacaaggtat atgcaactat agaagtagat
    14701 atgaagggta atcaaaatat agattttgat atttatgtca tagggaaaaa ggattcagat
    14761 acaactaagc caagtaatgt aataaatatt accaatggaa atggaaattc aaataatgat
    14821 aataatatta aagatatgag ggtagaaaat atatcagcta atgttgatag agataataat
    14881 gtcattagag ttaactggag tagtatatct cataaggact gtacttacag tatatatgta
    14941 aaaaataata ctaatggaga tggagaattt actctatatc aaagtgatat acagggaaat
    15001 gagcatacta taagtattcc tgaaggagat ttaaatctag atatttatgt tgttgcaaat
    15061 tataatggaa atagctctca aaatagtgat gttataaatg taagatagat ttgtatacaa
    15121 attgaaagtg ttgagtttat ttaaatatta aattaagaaa aaggatagta tagggtaatt
    15181 atactatcct tttttgttac aatatatagg tttaaaatct ctagtaatat aaattataaa
    15241 aagtcttatt tacacaaatc tatagatatt ttttttatta atcaatattg tcttaaattg
    15301 aacttagtgc ggcttctatt gcatgtatta ctgtcgtatc aaatagtgga atagaagtgt
    15361 cattttgttt aattaaaaga cctatttctg tacatcctaa tataacagcc tctgcacctt
    15421 gtttgccaag cttatctata atagataaga aagctttttt tgaagattca gatataattc
    15481 ctaagcaaag ttcattaaat attgtgtcat ttactattat acggtcttct tcatttggaa
    15541 ttaagacttc aattccatta ttaataatta catttttata aaaatcttgt tccattgtat
    15601 atttagtacc taataaggcc acttttttta tttctttttc ccttaatacc gtagcagtta
    15661 catctgctat gtgaagtaat ggaatatgta tactttcttg tattttatct gataccttat
    15721 gcatagtatt agtacagata acaataaaat ctgcccctgc ctcttgtaat ttaattgcag
    15781 catcagctaa aattttggcg cttttttccc aatttccact agattggcat tcttcaattt
    15841 cttgaaaatc tacactgtaa agtatacatt tagaagagtg tagtccacct aatctttctt
    15901 ttattactgt attaataact tgataatatg taatggtact ttcccaactc ataccaccaa
    15961 ttaagcctat agtcttcata ttatacctct cttatttatt tattttgaaa tagctattta
    16021 caaatacaag tatagcatct aaaatagaag catacaatga taaaattgta tggagtacaa
    16081 ttataattaa gaggagtaat tatatgccaa taaattcttt tgaaaactat cctatgacat
    16141 ggaaaccaaa attagataac cgaaaaccac caatatataa aactttagca atgttattag
    16201 aagaagatat taaaagagga aatttaaatc ctggagataa actgcctcca caacgggaat
    16261 tagcagattt tctagattta aacttaagta caataacacg agcatttaaa ctttgcgaag
    16321 aaaagggact aatatgtgca aaagtgggaa agggaacatt catttcttct gatgtaaatg
    16381 taagtaatac attattatat caaacggaat caaaagacat aattgaatta gggacagttc
    16441 atcctccgta tgagcaaaat acatatatta ttgactttat taaaaatgta ctaaaacaac
    16501 cagaaatgga taggttttta caatacatgt ctccatctgg cacatatatg caaaaaaagt
    16561 caattgcaaa atggatagaa agaaataatg tatacaccag tgaagaaaat atattattat
    16621 ctacaggagg gcaaaatgct atatgtgcaa ctttactagg attatttaaa gctggtgata
    16681 gaattgctac agattcttta agtttttctg gaattaagtc aatagctaaa atgataggta
    16741 ttcaattagt cccaattcct caagaaaata atgaaatatc gattgaatat cttgaaagtt
    16801 attgtaaaaa tgaaaatata aaaggcatat atcttatacc agattatcat aatccaacga
    16861 cacatactat gtctgattta tctcgtaaaa agatagccaa gatagcaaag caatataata
    16921 taataattat tgaagatgct ataaatagca tttttagaga tggtatacaa actcccatat
    16981 tttctttagc tagtgataat actatatata tttttagtac atctaaattt ttatgtgctg
    17041 gtcttagagt agcatttgta gttgctccaa aacgatatat agaaaattta gaaaatgcac
    17101 tatataatat gaatctaatg gtttctccat ttacagcaga aatagtacac cgtttattat
    17161 attctcctat tatagataaa attatagaag agaaaagaga tgcaattata gaaagaaatg
    17221 aagttgctga taaagttttg tcagattata atttgattgg tgataagaat tgcagttttc
    17281 gttggttact tcttcctgat gaattggatg gaaaatcatt tgaaatttct gcaaaaaatc
    17341 taggagttca agtatattgt gctgaacgat tttcagtagg aaactctaca gttccaaaag
    17401 cagttcgtat ttgtgtaaca gctccaaaag atgtagaaga attagaaaaa gggcttaata
    17461 taataaagtc acttcttaag agttaaattt attttactat tatttaatta aataaataaa
    17521 aaggcggaga aatttattat aataaacctc cgcttttatt atttaatgaa atactttact
    17581 ttttattaaa aaatttaatt ttaataatct tgaaaatata atcgttttat ggtaaaataa
    17641 ttcttaaaaa tagaaaaaat taatcatttg ttaaaaaaaa tgcataattt attgtaattt
    17701 attgacgaag gttgaaaaat attcataaat gtgcgaaata acagaaaaaa tgcaaaaatt
    17761 aattcaattt catttgttat aaaatctata tggcaaaatt aaatctgcct atcagaatga
    17821 tataaacaca ccagaaagga ggacgctatc aaataataca agtagttaac tttgatagca
    17881 aaaaattatg aatgaacaaa ctagaatatc cttagagaga gctgctgaat taaaatcaaa
    17941 aattgatgat tatattcagg ctagaaaaac gattaacaga ggtcttgaaa aagaagaaga
    18001 gataaataaa cgaaaacaga aaatattaag tatcttaaat ggaactgaag aggattggaa
    18061 taactacaaa tggcaattat caaatagaat aacagatgta gatactttat caaaaattat
    18121 aactctaact aaaaaagaaa aagaatatat aaaagaggtt ggtactcaat ttagatgggc
    18181 aatatctcca tattatttga gtcttataga cccagaagat acatgtgacc caataaaatt
    18241 actgtctata ccaacacata tagagttgga agatgaacaa gaagatttgg acccaatggg
    18301 agaagagtat acaaacccag caggatgtat aactagaaga tacccggata gattaataat
    18361 aaatgtaaca aatgagtgtg ctatgtattg tagacactgt cagagaagaa gaaatattgg
    18421 acaacaagat tctcataagt caaaagctat tatccaagaa tctatagact atatcagaga
    18481 aaatgaagaa ataagagatg tactagtaac tggtggagat gctcttacat taaaagatga
    18541 ttatttagag tggattctta gccaacttaa agagatacca catgttgatt atgttagatt
    18601 aggtactagg actcttgtta caatgccaca aagaatcaca gatgaatttt gcaatatgct
    18661 aaaaaaatat caccctgtat atataaatac tcattttaat catccaatgg aaataactaa
    18721 ggaatctaaa gaagcttgtg aaaagttagc aaatgcagga gttccattag gaaatcaggc
    18781 agtattatta aatggaataa ataatgataa atttgtaatg agatgtttaa atcaagaatt
    18841 actgaaaata agagtaaaac cttattatat attccaaagt aaacatgtaa agggaacaaa
    18901 acatttcaat acatcagtag atgatggtct tgaaatcatg gagtatttaa gaggatatac
    18961 atcaggaatg gctataccaa catatatagt aaatgctcca aaaggaggcg gaaagactcc
    19021 tttgcttcct caataccttg tatcaaaagg aacagattac gttatgctta gaacatggga
    19081 aggaaaagtt ataaaaatgg aagatgaacc tgctgtagat ataaagaaac ttataaaaga
    19141 acaagcgcag gattaaaaaa gtatttaaag tttataaaaa gaaacaactt taaaataaaa
    19201 agaaaatgga tgtcaaattt atatcaattt gcatccattt tttattagtt atttattatt
    19261 ttgttgttga ttaactaatt caagatatcc acttgggtgg aagtaatata tctcagaagt
    19321 attttcattt acaaagtaac caatatcacc atctgcatct ggtaaaaata cataaccatt
    19381 aagattttta gcttttaatg cttcaaaatc actagcattt ccttgatata tgtaatcaac
    19441 ttcattgttg tattttacta aaagttcttt agcttgttct tgagtcaatt tagtattttg
    19501 gcttacagga acattctttt gagaatctgc ataagaagat tcatttactg gtgcagttaa
    19561 taacaaacaa gataaaacta ataaagatat aagtgctttt ttcatactaa aaccctcttt
    19621 catgtttaat tatataagat tcattactta ataatattgt atgtttccta taattaaata
    19681 ttaccattaa agagaataat attacagtta cacagctgta acttttgatt acaaaatcgt
    19741 aattaaattg tatttttatt ccatttgtat tttatcatgt ctacgattta caaactcaca
    19801 gaagtatatc tttataacgc ccatcacagg agcagataga atcataccag gtataccaaa
    19861 gaatcctcca ccaacagtaa ctgctaggat tgtaaagaat gggctaagac ctagttgtcc
    19921 acctacgatt tttggctcta taaatgtaac ttcaacttgt tgaattatta ttaagtaaat
    19981 taaagaagtt aaagcaattg ttggattgga gaataaatta attattacaa ctggtgccat
    20041 acctattact ggaccaaaat atggaaccat attcatgaca cccataagtg taccaaataa
    20101 tagtgcatat tcagatttta aaaagtaaag accaattcca gaaagtactc caactataaa
    20161 agaatctaaa atcttacctg taaagtattt accaatattt aaatttaagc tttgacatag
    20221 ttctattata aagtctccat attttttacc taaggaaata taaactactt tttttgtaaa
    20281 cagtaagaat ttttcttttt ctaataatat atagaaacaa attataaaac ctaaaagaaa
    20341 ttgtactata aattttccaa ctgaaaatgt agtgctaaat atcccaccaa gtgaaccaat
    20401 aagcaagtta ctaaatttag gcattacact cataattttg tcaccatact cttttaatgt
    20461 attagggtca actgattgta aactcttgcc taagtcgaat aaaaactgct ctgttttatc
    20521 tatgtatgta ggaatttgag caactaaatc agctaaacta tttactatgg atggaactgt
    20581 aaataatata aacgaaatta gtataactat gagtacacca taagtaagaa gtaacgaata
    20641 tattctctta aaatttaatt tactttctaa gaactttact agtgggttga atatatatgc
    20701 taatacaaat gctattataa atggtgttag tagtgacatt aataaactta tcactccaaa
    20761 aaaatatttg taattatcaa taactttaat caagatatat gaaacaacta cagtgagtac
    20821 aatatttaga taaatttttt tatcttgcaa aataacacaa cctttcttat atttattaaa
    20881 tttagatata cttaaatcta agttaaagtt aatatttata gcttattata caataaaaag
    20941 cagtattaat atagtatgat taatatgaaa ttataaatac gttaaaactt tatgtttata
    21001 gctaaaataa taaaaattat ttatattgtg tttatatata atctaaaatg aaaaaaagtg
    21061 gtgcctttga ttaaactaag tttttataat ttaaattttg tacaataagc tatcttttat
    21121 tattctttaa aatatatatt tcatttaatt atgacaaata aagataaaaa ttaaatattt
    21181 tagaggtgat tttatttaga tatagaattt tagaataata ctatacaaat gtattgtatt
    21241 attattttta tatcaaaaat agtaataaag tctatataca tttagaaaat actgtttaaa
    21301 aggagtagga tttatgataa aaaaagagat atctaacttt agaggaagta gtgattatgt
    21361 agtatcacca gaattgatgg catcagttaa tgttgctatt gctcttgaaa agccactttt
    21421 gattaagggc gaacctggaa caggtaaaac tatgctagca caagcaattt caaatgaatt
    21481 aaaaaaagat ttagtaattt ggaatataaa atcaactaca aaagcacaag aagggcttta
    21541 tgtatatgat actgttcaaa gactttatga tagccaattt ggaggagaag gtgtagatga
    21601 tattagcaag tacataaaat atggtaaact aggagaggcc tttagctcaa atcaacaagt
    21661 aattctttta atagatgaaa tagataaggc ggatttagaa tttccaaatg acttgctttg
    21721 ggaattggat aaaatggagt tttacataaa tgagacaaaa gaaactgtaa gagctaaaca
    21781 aagaccaata gttattataa cttcaaatgc ggaaaaagaa cttccagatg cttttttaag
    21841 aagatgcata tttcattata tagaatttcc tgatagagac atgatggaag aaatagttaa
    21901 agtacatttt gataaagtag aagaacacct attggaacaa gtaatgacta ctttttattg
    21961 gattagaagt ttaaaggaca tacaaaaaaa gcctagtaca tcagagttaa tagactggat
    22021 acaagcatta actttgagtg gaatgcctat tgaaaaaata gaaaaagaag ttccttttgc
    22081 aggaatacta cttaagaata atgaggatat tgaatctatg caaagacact tatagttaat
    22141 aggagctgga taattatgtt tattgaattt ttttatttat tgaggtcaag aggattaaat
    22201 gtatctttaa atgaatggat gactttaatt gaagcattgg ataaaggact gtgctattca
    22261 aacttttcaa atttttacta tctttgcagg atgattttaa taaaaagtga aagtgatttt
    22321 gataagtttg atgcagtgtt tttggagtat tttaaaggta tagaacacca agaagaaatt
    22381 ccagaagaga ttatgaattg gcttaaaaaa ccagatatag atttagaaga gtttgaaaga
    22441 ttagaacaaa atccaaatat aaatcttgat aaattaagag ctaaattgga ggaacgaata
    22501 aaagaacaag attctcctca taatggtggt aattattgga taggcacagg aggcacttca
    22561 gagttaggac attcaggaaa agggcaaact ggtatacgta taggtggaaa ttctacttat
    22621 ggtagagctg ttcttgaagt tgcaggagaa agaaaataca gagattttag agatgatgaa
    22681 gttttaaata tgcgtcaatt tcaagttgca ctaaagagac ttcgtcaatt ttctactaga
    22741 atagatgctc caaagacaga gcttgatttg gataagacta ttgaagagac ttgtaataat
    22801 gcaggatatt taaagttatt ttttgagaag ccaagaaaaa atacagtgaa gcttttattg
    22861 cttatggatt caggtggttc aatgagaggg tatagcactt tatgtaatac attatttcag
    22921 tctgtaagta aatcaaatca ttttaaagat gtaaagatat attatttcca taactgtatt
    22981 tatgatagat tatttacaac acctgaatgt tggttaagta aatctattaa tactgaatgg
    23041 atattaaaaa atatagataa aaactataaa gttataattg ttggagatgc ttctatgtcg
    23101 ccttctgagt tgcttcatat tggtggtaac tatcgtggtc catataatta tacacctggt
    23161 atagagtggc ttaaaaggtt taagagaaag tacagtaaaa ttgtatggat gaatccagaa
    23221 cttagagatg gatgggattc aattagttat tggtatcaaa ctcaaagaat gatacaaagt
    23281 gaatttaata tgtttccatt gactgtaaaa ggtcttgaga aagcattgaa aaatttaatg
    23341 gtttcaagat aaagtaaata taaatgatgg tatgatttat tcaaaattgt accatcatta
    23401 tttatttttt taatatatct attataaatt gtataactga aacttaaaaa attatatagt
    23461 ctaatacatt ttagactcac acaaaacata tacattaata ataattttag aagtcgaggt
    23521 gattataata aattatgaat taattgtaaa atacaatgga gatatattga ggttagaaga
    23581 agaattaggt gtatcagtag agatacttaa ttcatcatat gcaataataa catcaagtaa
    23641 tgaagaagat gtaaatatac ttttaactta tccagaaatt gaatttatag aaaagccttt
    23701 tatattacag actcaggatg tgcaaagttt ttcaagtaca ggaataacag gatttaaaaa
    23761 tagaactggt ttaactggaa aaggaactat aattggtata attgattcgg gaatagatta
    23821 tactctacct gtgtttagag atagtgatgg aaggtctaag atattatatt attgggacca
    23881 atctattcaa ggaaatccac cagaaggttt tagagaagga acattatata ctaatgaaga
    23941 tataaataat gcaatagatg gaagtatgta tatacctatt tcaacaacta gcttacatgg
    24001 aacacatgtt gcaggtattt gtgcaactat tgcaagtgat gccagaataa tagtggttag
    24061 agttggaaat atacagaccg atattttttc gagaagtaca gagtttatga gggcaattaa
    24121 atttatttta gatagggcat tagaattaag aatgcctgtt acattaaata taagttatgg
    24181 aagtaatgaa ggttcacata gaggaacatc tttatttgaa caatatatag atgatatgtg
    24241 tttattttgg aaaaacaata tagttgtagc agctggaaat aatgcagata aaggaggtca
    24301 taaaaggatt aggcttcaaa ataatattac agaagaagtt gagtttatag ttggggaagg
    24361 agagcgtata ttaaacataa atatatggcc agattttgtt gatgatttta gtgtacattt
    24421 ggtaaaccca tcaaataatc aaacacaagc aatctctcta acttcaggtg agataaggaa
    24481 tactttgggt gaaactagaa taactggtta tttttaccct atagcaccgt attctctcac
    24541 aagaagagtt actctacaat taagttcaaa tacacagata actcctgggt tatggaaaat
    24601 tgtatttgaa ccaatagata tagtaactgg taatgtaaat atatatttgc caacttctga
    24661 aggtctaaat agaaatacta gatttctgat tcctactcaa gagcttactg taacagttcc
    24721 tggaacagca agtagagtta taacagtagg tagttttaat tcaagaacag atatagtatc
    24781 tatattttct ggtgaaggag atacacaatt aggtgttttt aaacctgatt tattagctcc
    24841 aggtgaagat atagtatctt ttttaccagg aggtacaagt ggagcattaa ctggaactag
    24901 catggctaca cctcatgtta caggggtttg ttcattgttt atggaatggg gaattgtaaa
    24961 tggaaatgat ttatttttgt attcacagaa attaagggca ttacttctaa agggagcaag
    25021 gagattaagt aatcaatctt atccaaataa ttcatcagga tttggttttt taaatttatc
    25081 agatatagat ttgtacactc tatctaatat aaatcaagat ttagaaacag aggatattgg
    25141 atatagaagt attaataagt catttaaaga tgaggaaaat agttataagt ttatagatgg
    25201 ttataatatg caaatacata atgacttaga gaatgaaatt tatataagta aaaatgcaag
    25261 tagacaatca ggaatactat caggaataga tatagtccat actcctgaat ttgaagaaga
    25321 actagctggg ttaggtatga gtcaaaggtt ttttaagata agtgattcat taggtgtact
    25381 atctataaat aatacagact ataatagcat acaacgagtt ttgcaacttc cttcaatcat
    25441 aagaactgta tcgactacaa agatgacatt acttggagaa attaatcgag gtacttttgg
    25501 aggtgtagtt gcaacagaag aaatgggcgt aaatttcttt aaaaataatc ctaatattaa
    25561 tataacagga agagggactc taatatcaat tgcagataca ggaatagact atctacaccc
    25621 agattttatt tatccagatg gcacttcaaa aatagtatat ttatgggacc aaacaaaaga
    25681 aggaactcct cctgatggtt tttatattgg gacagaatat acacgagaag atataaatcg
    25741 agctatcgca gaaaatgacc ctagtctatc tcaggatgaa gttggtcaag gaactatgtt
    25801 gagtgggata tgtgcagggc ttggaaatgt aaatagtgaa tatgcaggta tagcagaaga
    25861 ttctgagcta ataataataa aactcggcaa gatagatgat ttttataata gtgcaatgtt
    25921 gtttgctgca tctcagtatg catataaaaa agcttttgaa cttggaagac cattagttat
    25981 aaatatgtct ttaggtacca gtagcctagc aggtttaacc aataggagta atagtgaaaa
    26041 agcgttcttt actagagggt tatgtataac ggcaggagca ggaaatgagg gcaatacaca
    26101 gacacataca tctggaataa taccatatgt tggaggttct gttgaagttg aattagagtt
    26161 aaatgaagac gaggaagaat tatcattaga actttggtta aatagaccag ataaagctga
    26221 tgtaataata gtatctccca ctggtgaaga aagtaaaagt gttggaattt caaattataa
    26281 taaagtaaca ggtttatttg atttagaggg gactgaatat tctataacat atatataccc
    26341 aacaactttt tctggacagc aatttactaa tgttacttta aagaatgcaa aaagaggtgt
    26401 atggaagatt cgattagtag gagtttatat tataacagga agatataact tataccttcc
    26461 aaatagagaa cttttaaaaa gtggaactag atttagagag gtagaccctt tttacactat
    26521 aaattatcct gcgattcaag atgatttaat aaccatagga gcctacaata ccattaatgg
    26581 tagtttatgg caaagttcat caagagggcc aactattgaa gacaggttaa aaccagatat
    26641 agtagcacca ggtgtcaata taatagctgc ttatcctggg aacacgtatg caactataac
    26701 tggtacagca gcagcaagtg cacatgcagc tggtgctgct gcaatgtatt ttcaatatac
    26761 ttttgttgac ggtagatatc caaaccaagc atatgtgcaa aaaataaaaa cttttatgca
    26821 agctggtgct agaaaagatt caaacacagt atatccaaat acaaattctg gatatgggct
    26881 cttggatgtt agaggaatgt ttgatgtttt aagataggag ggatttatgg aaaaatctta
    26941 ttgtataatt tatcaaggtg atatagaatc tgccctacaa gaaaatggaa taaataggta
    27001 tatggtttta aatagtcagc ttgcagtaat atatgtacct ttagattttg atgaaactat
    27061 tttaaataat ataatacaag ttgcttggtg ggaagaatct gaaccaatga gcagtctaat
    27121 tgaaataact aataatgtaa ataatggaga aaccattaca acagcagctg aaactgatta
    27181 tatttatgaa aatccatata atgatataac agggagagga attttattag cagttataga
    27241 ttctgggata gattatttgc atcctgattt tataaatgat gatggaacta gtaaagtttt
    27301 atatttatgg gaccaagaag caaatacaaa tccacctcca gaaggtttta tttttggaag
    27361 tgaatttaca agaagtgagt taaatatagc cataaataga aatgatggga gtttgagtca
    27421 agataatata ggtactggaa ctttagtttc tggtatatta gttggaaatg gaaggataaa
    27481 ttctcagtac agaggtatta ctacagaatc agacttaata gtagttaaat taaaatcata
    27541 tacagatact tattatgctg gaaggataaa ttacagtgtt tcagattttt tagcagctat
    27601 aacgtatgtt actaacatag caagaacaga aaataaacca ctgataataa atttgactat
    27661 tggagttaag tcaagtgctg tagcaactac ttcaatacta gatactttta atatattgag
    27721 tagtgctggt gtggtagtag tgagtggtgc aggaaatcaa gggaatacag atattcatta
    27781 ttctggcaga tttagcagtg tgggagaagt tcaagatgta ataatacaag atggagatga
    27841 ctatgctctt gatataacac taaatacgaa tggtccagat aaagtgggag cacagataat
    27901 atctccttca ggtgaagtta gtcatgatat aaggtattct ccagactttt atatatatag
    27961 aggaaaattt aacttagaaa atactactta tgcaatgaga tttatttatc catatattac
    28021 ctctggaaaa gaaaatttgg agataagatt aagagatata aaacctggag tatggatttt
    28081 aagattgact tcagaactta taataaatgg agaatatgac atatacttgc caaataaaaa
    28141 tttgatagct ccagacacaa ggtttttaga gcctgattca gtagctacta taactatgta
    28201 tgctgctagt gatgatgtaa ttacagttgg tacatttaac aataagactg atagtatgtg
    28261 gattggttct tcgaaaggac caattagagg aagaggaatt aagccagata tagtagcttc
    28321 aggtgtagat ataatatcca catataaaaa tggaacatat aatacaggaa caggaacagg
    28381 agtgagcagt tctatagtca caggtgtttt agccttattg atggaatact tagaaaaaca
    28441 ggataatgta ccgagattat cattgtttac acaagtttta aaaacatatt taatattggg
    28501 tgctacaaaa cttgagatat atacatatcc aaatgtatcg cagggatatg ggattttaaa
    28561 tttaaaaaat acgattcaac agatagcaaa tactctatag ataagaacct atgtaaaatt
    28621 ataattgatt attagtttaa ttgtatcaaa tactttagat agagtagaaa aatagcataa
    28681 aaaataaata tgaaaattaa aaaacagttt tatattttga atacacaaag taaatatttt
    28741 gtatataaat aggtataaat taagtattga aaagatatta tgttaattta aaaataatta
    28801 taatttagac ttatgaattt tatttgtaaa attgctaaaa ctattacaaa ataaataata
    28861 gaggtgatag ttttggaaag taaaaaggca agagcattaa aaggtaaaga taataaaaga
    28921 cttaaaagtt cacttttagt tggaaatgag tcgacagcag catgggctga tgttgaaaaa
    28981 ttaaaacctc atagtaaagt ttcaatacct tcaattaagg gtgtcgaaga agcaaaagac
    29041 tgggttgaca atggaagtaa attataaaat tttggaaatt gaagtaataa agaagtaatg
    29101 aagataagta tttattatca ttatgtaagg tagaattatt atattttaaa taacaatcag
    29161 tatcaattat ataaatttat tgactaaaaa tttataaatt ggtataattt tgttaattag
    29221 cagaaataat aaaagataaa tactgtgaag agaagagtag atataaaatg tagttctagc
    29281 gagttgagga tggtgaaagc tcaatacgag gtttatattg aagaacatct tggagtttct
    29341 aatcgaaagc ttatttagta agtagactta gacggaaggc accgttatag gctttaagca
    29401 ttgcttaact aagaggtcat tatgacaact agggtggtac cgcgagagta atagtctttc
    29461 gtccctttat atagggatga agggcttttt ttattgaaat tatatttaaa agaaattaat
    29521 aacaattata ctaggaggat ttaaaatgca aaaggaattt ataacagtaa aagaattgta
    29581 cagagaaaaa gaacagtaca tagggaagac tgtaaaagta gctggatgga taagaacatc
    29641 tagagtatct aaaaattttg gatttataga gctaaatgat ggaagcttct ttaaaaatat
    29701 gcagatagta tttgatgaga aagtagaaaa ttttaaagag gtaggaaaat tagcaataag
    29761 ctcatctata cttgtagagg gagagttagt atctacagaa ggggctaaac aaccagtcga
    29821 aatacatgca aaaagcatag ttgtagaagg ggaatcagat agttcgtatc cactacaaaa
    29881 gaagagacat acgcttgaat atttaagaac gatagcacat ttaagaccaa gaagtaatac
    29941 tttttcagct gtatttagag taagatcaat agctgcctat gcaatacaca aattcttcca
    30001 agaaagaaac tttgtatatg cacattctcc aatcataaca ggtagtgact gtgaaggtgc
    30061 aggagagatg tttagaataa caactatgga tttaaatgat attccaaaaa ctgaagatgg
    30121 caaaatagac tatactcaag atttctttgg aaaagaggct aatttaacag ttagtggtca
    30181 attaaatgcc gagataatgg cactttcttt tagaaacgtt tatacttttg gacctacatt
    30241 tagagctgaa aactcttata caggaagaca tgcttcagaa ttttggatga tagagccaga
    30301 aatagttttt gcagaccttg aagataacat ggaacttgca gaagatatga taaaatatgt
    30361 tataagctat gtattagaaa atgctcctga agaaatggaa ttttttaata gttttataga
    30421 taaaggattg ttagaaagat taaataagat agtaaactct gagtttatta gaataacgta
    30481 tactaaagca gtggaattat taattgaatc tgggcatgaa tttgagtatc ctgttgagtg
    30541 gggatgtgac cttcaaacag agcatgaaag atatataacg gagcaaatat ataattgtcc
    30601 agtgtttgtt acagattatc caaaagatat aaaagctttc tatatgagaa tgaatgaaga
    30661 tggtaaaact gttagagcaa tggatttact agttcctgga gttggagaaa tcgtaggagg
    30721 ttctcaaaga gaagaaagag aagatgtatt gttagataga attaatgaaa tgggattaag
    30781 agaagaagat tattggtggt atttagaact tagaaagttt ggtactgcta ctcactctgg
    30841 atttggtctt ggatttgaaa gaataattat gtatatgaca ggtatgtcta acataagaga
    30901 cgttatacct ttcccaagaa ctcctaaaaa tgctgaattt taataattat atataataaa
    30961 acttatataa ctttaagtat aaacactaaa atgacttgca tatttatcta ttttagagat
    31021 atgcaagtta tttttattgt actataaata tataatttga ttacttttat tttgcgatat
    31081 aatacttata ggtttatgta atagtatgta accttttaat aaaatgcaac acaattacgt
    31141 ccttgttctt ttgcagtata tagggcctta tcacaattac ttataaactc atttaatgtt
    31201 attgtctttc caattttctt tgtataaact ccaatactaa cagttacaca ttttaaagga
    31261 acatcatcac gctcaaaatt gcaggactct ataatttttc gtaaacattc tgatttaagt
    31321 ttagcatctg cctcattaca gttaaaaata catataaaaa attcctcacc accatatcgt
    31381 atagcatgtt cattttcaga acttgtaaaa tctaaaatta ctttggcaat attttgtaga
    31441 caatagtctc ccttttgatg tccataatta tcattaaatt gtttaaaata atctatatct
    31501 atcatcattc cagttatagg ttcttgattt gcatggctga ttaatttttt ttgtagaata
    31561 tcttcaaggt acctacggtt gttcatttta gtaaggtcat ctgtcataac tttgtcgtta
    31621 agtaaattat ttatatgaga tatttcttca tattgttgac taattaaaag tttatcatag
    31681 taagtaaata cacgatttct atatagcatt gtagaaacaa aaatggcaag ggatgttata
    31741 aaaaatgtgt tgacaatatt actaaactca ttgcctggta tagtttgaat cccaggtaag
    31801 aataaattaa gaaacaaaaa gcatcctcca aaaactatta ctgattctcc aaattttaat
    31861 actgagaaag ctgcagctgc taacataata taactaaata cacttaggtc atttccacct
    31921 aactggtcaa gtagagtaat tacacaaccc cataggcaga aaaaagtcac ataaattatc
    31981 cataaattta tataaaacgt acagcaatcc ttttttttat tccaaaggta agaaaataca
    32041 aacataaaga cagaagatac acaaaatagt gttacataca tataaaaata ccattggcgt
    32101 cttggtgtga caaaagggcc tccttctcta gctgagattg atatcatcat aattatttga
    32161 gatattacta ttattatgca aatgatttta cccgtatgat aaagataatt gcagagttct
    32221 ttctcaacat tgtctttgtg ttttttgtct agaggaaatc caaaaaattt ttttattttt
    32281 tctaagttca tataagcctc cattaaaaat aaagcataaa aataagtatt cctttctatc
    32341 attagatatt tggaatactt cgtttatgat ttaattatat caaaatatat tgtgtgtaac
    32401 aatctaaaat tgtgatagat aaaatttatt agataatgtc gagtaacttt attgattaat
    32461 actttattat aattaagatt tacagatagt ttactactga aaataaagaa tagaataaat
    32521 ttaaattaag cataataaaa tataaataat aaagttcgca ttaacaaact atttaaatat
    32581 caagacctgt taaaaaacaa cagcaataaa caaataaaat agataaatat atccaattaa
    32641 ggtataatta agttttatat gatatagtta tatttgataa tttacaatag taaaacttgg
    32701 agggaaaaaa tgggtgaaaa gaaaataaat aatatgaatt attcacataa taattattcc
    32761 aaaaagacag gtgaaccaac tagaaaaata aaaaatagcc atatcactct taaaagtaaa
    32821 gaagaaaaaa tttgttctag ttgcaataaa gaaaataata ctaaggataa ttactgtaaa
    32881 ttttgtggaa atgaacttta tgaaatagca tcattaagac cacttgaaac aaaactagac
    32941 ttgaaatcta aaataaaaga gctttcatat catgcaaata aaagaggtgt atttttaaca
    33001 acatttacaa ccatatttat attgtttatt attgcattga tatttaaagc tattataact
    33061 attcaattta atgatattag ttatttaata aatccagcac atataatcct agctctcaac
    33121 ttgggtcaaa ttagtgtatc tatgtctacc atgatgggtt ctgggtttat aaatgccaat
    33181 ataggtttgt tgatattact tataatccct attttggtat tattaatatc aaacctaatt
    33241 tttatgagaa aaagatgtag agattcaaaa actgtattag caaattctct aggagttgga
    33301 attttttatg gattagtttt agctatttta tctattttta ctaatgtaaa aactagttca
    33361 catagtatgt tagaatatgg atatgcatta gaatatagtt atgaattttt tagtgttctt
    33421 ttaaatggat ttgtattagg gtttatatgt acatacataa ctacttataa aaaaagttat
    33481 gaaaaggaaa atatgtattt atctcttttt tcaaattcta taagaacatt catattaggt
    33541 tatgttttag tattagtaat actattggta ctaactatat ctgatagtag ttacttaaat
    33601 gaactagata tgagtagtta ttcaaatgga ttaaatttat ttactatact cccacaaata
    33661 gctagttata tgtgggcttt tgcaaatgga atttcagtaa ccataataaa ctcaacagta
    33721 tcaatgttta ctttaagttc ttcatcttta tttggagata ctaaattaat gttttatgca
    33781 atgggagcat tgtctatgtt aatattatta ttaaatggat acaagctaag atttaagtat
    33841 aatacagata gtataagacc tataatagta tttagtatat attatgcatt tttgatggga
    33901 atattggctt tatttagtac atttatacta gatagtaata ttaatttctt taatacaact
    33961 aattatggaa caactttaat aatgcaattt aaagtcttac aagctattgt aatttcattt
    34021 gtatatagtt ttgtgatatc tttaatagga tataagctaa attcagctga ttaaatatga
    34081 ttggagggaa tttctgtgga aggaaatact aataataaag tagatgataa attttctaag
    34141 gttaagaaaa agtttggtag tggaaaattt aaagttgaat tatataaaga aaaatcaaaa
    34201 ttaaatagag agattgatga tattcaagaa aagaaagcaa agatattctt ggaaatggga
    34261 atactgacat atcaaaaaat tagagaagat tctattaatg ataatagttt tgataaattc
    34321 tgtgatgagt tactagaact tgataagtta atttatgaaa aaaatatgga aattaatgaa
    34381 atggaaatgg cagaaagtaa tgtaacttgt gagtgtggtt atgttggaaa tgtaaatgat
    34441 aaatattgtg ctgaatgtgg taaaaaattt gaattggaaa atgaatgtga tgattttata
    34501 atttgtggtt attgtgaaag tgagatagat acagaggctg aattttgtcc atgctgtgga
    34561 agaaaaatta taatggattt agaataatat tgggaaacct atgtatagta tacatgggtt
    34621 tttttattga aattatttaa atggacttat aacagtagtt atataaaatg aaaataaaca
    34681 ccaaaaaaat gaaataaaat ttcttttaaa tgtaaaaaac aagctaatat ataaaataaa
    34741 tcagtaaaaa tatagatgcg agaaaaaaat atgaaaaaat attgcaaaga aaaagttttc
    34801 atgttattat taatacataa atcaagaaaa taaatttcag aaacgaggta atttaaaaaa
    34861 tgctagataa ggtaaaggga agattaatag tatcatgcca agctttagaa gatgaacctc
    34921 ttcatagtcc ttttataatg gggagaatgg ctaaggctgc tatggaaggt ggagctgttg
    34981 gaattagagc tcaaggagtt gaagatatta ttgaaataaa aaaagttact ggacttcctg
    35041 ttataggtat tataaagaga aactatgaag attcagatat atatataacg ccaactaaaa
    35101 aagaagttga tgaactttta acaacagggt gtgaaatgat agcattagat gctaccaata
    35161 gagttagacc aaataatgaa gacttaaaag aacttataaa gtatataaaa gaaaacggtg
    35221 ttctagtaat ggcagatatt tcaaattatg atgaggctat caaagcacaa gagtacggtg
    35281 tagattgcgt ttcaactaca ctatctggat atactccata tactaaaaca ttagaaggtc
    35341 cagattttgt attaatggaa agattagtta aagatttaga aatacctgta atagctgaag
    35401 gaaaggtaaa tactcctcaa gatttaaaaa aggtctttga gttgggtgtt cattcatcag
    35461 tagtaggttc agcaataaca agaccacaat taataacaga aaaatttgtt aaagcaattg
    35521 aaattaatta aaaattaatt tataaattaa aaaattatta tatttaacta tatttgaaaa
    35581 ttaaaattgg aggtaaagat atgagaacaa cagatatgaa gggaatttat tcagcattat
    35641 tagtttcatt tgataaggaa ggaaatataa atgaaaaagg gttaagacaa ataattagac
    35701 acaatataga tgtttgtaaa gtagatggtc tttatgtagg aggaagtaca ggggaaaact
    35761 tcatgctttc aactgatgaa aagaaaagaa tatttgaaat agctaaagat gaagtgaaag
    35821 aagaaataaa attaatagct caagttggtt cagttaattt aaaagaagct gtagaacttg
    35881 ctaaatttac aactgattta ggatatgatg caataagtgc tgttacacct ttttactata
    35941 aatttgattt tgaagaaata aaacactatt ataatacaat aataaattct gtagataata
    36001 gattaataat atactctata ccatttttaa ctggtgttga tatgagttta gaccagtttg
    36061 gagaattatt tgaaaatgaa aaaataatag gtgttaagtt tacagcagca gatttctact
    36121 tattagagag aatgagaaaa acattcccaa ataaattaat atttgcagga tttgatgaaa
    36181 tgatgttacc agctacagtt ttaggtgtag atggggcaat tggttctaca ttcaatgtaa
    36241 acggtgtcag agctagacaa atattcgaat taactaagaa tgaaaaaata tcagaagcac
    36301 ttgaagtaca acatgtgact aatgatttaa taacagatat attaggaaat ggcttatatc
    36361 aaacaattaa attactactt gaagaacaag gtgttgaggc tggatactgt agacaaccta
    36421 tgaaagaagc aactgatgaa atgaaatcaa gagcaaaaga aatatacaga aagtattttt
    36481 aataaaatac ttttagtatg ggaggattag tcaaatggta ggatttactt ggatagattt
    36541 tgcaatacta gtggtttact tattggcagt tttatttgca ggattgttat tttcaaaaaa
    36601 ggaaatgaag ggaaaagagt tcttcaaagg tgatggaact attccgtggt gggttacatc
    36661 agtatcaata tttgccacat tattaagtcc aatatcattt ttatcattag caggaaattc
    36721 ttatggtggt acttggattt tgtggtttgc acaattaggt atgtttatag caataccttt
    36781 gacaataaaa tttttcttac ctctatatag taggttagaa atagatacag catatgaata
    36841 cttagaaatg agatacgaaa gcaaaggtct tagagtactt ggagctttga tgtttataat
    36901 atatcaaata ggacgtatgt ctatcataat gtatcttcca tcaatagttc tggctggtct
    36961 tacaggaata cctgtaaatg tactgataat agttatgggt gtaatagcaa taatttactc
    37021 atatacaggt ggattaaagg ctgtcttgtg gaccgatttt atacaaggaa tggtattaat
    37081 agtaggtgtt acagggacat tgttctattt aatagcaagt ataaatggtg gttttggaac
    37141 agtaatggat actcttacaa ctggacacaa gttcttagca agtaatgaag ttatgtttga
    37201 taaaaatata ctatctacaa gtgcatttat aatatttgtt ggagctggtc ttaatacttt
    37261 ttcatcatat gtatcgagtc aagacatagt tcaaagattt actacaacaa ctgatataaa
    37321 gcaacttaat aaaatgacat atggaaatgg tgttttatca atgggacttg caacagtatt
    37381 ttatctaatt ggaacttgtt tatttatata ctatactcaa aacccagatt tagctcaaac
    37441 agttcaacaa gaccaagtat ttgcatcata tatagcttat gaattaccag tgggtataac
    37501 aggaatacta cttgcagcga tatatgcagc ttctcaatca actttatcga cagggcttaa
    37561 ttcagttgct acaagttgga ctttagatat acaaactatc ataacaaaag atataagtat
    37621 ggaaaagcaa actaagatag cacaatatat atcattaggt gtaggtatac tttctatagc
    37681 tgttgcaata gtattagcaa atggagaaat aaagtcagca tatgaatggt ttaatagttt
    37741 tatggggcta gtactaggtg ttttagcagg aatatttgta cttggtgcat tttgtaaaaa
    37801 agcgactaaa atgggagcat atgttggatt catagtatca gcaattttag ttgtttattt
    37861 aaaataccgt atgccagaag taacttcttg ggcatattct ctaataacaa tcacgacttc
    37921 tgtagtggta ggtacaatag ttagtgcaat agaagctaaa gttaaagcaa aagtatcttt
    37981 accaaaagct gagactactg tttattatga aaaataatat ttaaatgata aattgtctta
    38041 tagagtgatt agataaataa tttagttact ctataagatt gtataatata ctttgtatat
    38101 aaaagtataa aaatagactt tataattata tagggagata gtgcttatga tatttggaaa
    38161 tataaatcat agtaagacat attcaacatt gcatgaagat ttacttagat gttttgaata
    38221 tgctaaagat aattcattaa tagattatga aaaaggtact tatacaatag atggtgatga
    38281 tatttttgtg aatattgtag agtataaaac ttgtgaaaaa gaagatagat tctgggaagc
    38341 tcataagaag tatatagatg ttcatttgat gcttgatgga tgtgaacgaa tagatataaa
    38401 ttttatagaa aatttagaac aaaaaatata tgaagaaaag ggcgatttct tgcctcttga
    38461 tggtaaaaat aatggataca tggaacttag aaaaggtgat tttttagttt gttatccgga
    38521 agatgctcat atgacaggaa taaaagtttt agaaaaagaa aatatcaaaa aagctatttt
    38581 taaggttttg gttagataat gataatttat ataaccacta gggctgaaaa tagtgattta
    38641 actttcagcg attagtgaga cttcgtaaat tttagttaga ttactatttt cagccttagt
    38701 tttttatgag aaaattgaaa ataattaaaa gcttaaaatt ttgtaaagga gttaacttat
    38761 ggaaaatata gatgtattct tattaatagg acaaagcaat gctagaggat tgggaaatcc
    38821 aaaagagagc atcattccaa atgaaaattg ttttgaatat ttgagtactg atgaaattat
    38881 aaatatgaga tgtgagctag agacttcaga aggtgatggt actatagcac ctgcattttc
    38941 aaatgaatgg aataagctta ctggaaataa agtttgtttt attcacaatg caaaagatgg
    39001 ttcaagaata aaaaactgga atcatgataa taactggttt ctaaatgaca ctatagaaaa
    39061 atttaataca ggctgtacta ccttaagtaa acattataat atagaaaata aatacgttat
    39121 ttggattcaa ggtgaaagtg atgcaaaata tggtagtgat gtattgtact ataaagaaag
    39181 tctaaaaaaa attgcgtata ggcttaaaga agaatgtatg attgataaaa tgtttgtaag
    39241 tttaactggt tattggcttg gagaagatga atattttatt agaacaagac gaattgcagc
    39301 agcacaggag tcggcttgta gtgaatgtga tatattatgt gtaggaagca aaattgctat
    39361 gcagtttcat gacagaggat taactattga tgatgttcat tacactcaag aaggtcttaa
    39421 tatgttagga gaggacttat gtaaaaatat ttataagtat catataacca aagaaaaaag
    39481 tgtattaagt gatactatag acttatcaga agcaaggaaa tatatctgtg aattggaaaa
    39541 gataagtaaa agatttgtgt aatataaaat tttaaataga gttgttaatt tataaaaata
    39601 atttgtatgg agatatgtta tgaaaaatta cgtttgtata gatgttgggg gtacttcaat
    39661 aaaatatggt tttattagag aagatggatt tataattgat aaatcaagtc ttgatactga
    39721 agcaaaggaa aaaggtggag aaggaatatt agccaaaata aaagatatag taaaaaaata
    39781 tatagaggaa aatgaaataa gtggtatatg tatatcaact gcaggtatgg ttgacccagt
    39841 tgaaggtaaa atactatttg cattagaaga attaattcca aactataagg gcatgcaatt
    39901 aaaaaaagaa gtagaaaaag agtttaatat aaaatgtgaa gttgaaaatg atgttaattg
    39961 tgctggactt ggtgaaatgt ggcttggagc aggtaaagat gcaacatctt ctatatgttt
    40021 aacaataggt actggaattg gtggatgtat tataataaat aataaactga taaatgggtt
    40081 tagtaatagt gctggtgaag taggatatat gaatgtaaat ggaagttctt ttcaagaatt
    40141 ggcatctact agcagtctaa ttaaaaaagt agcaaaaata aaaaatttga atgaaaatga
    40201 cttaaatgga aaaataattt ttgatttagc aaagaataat gatgaagatt gtttaaaaga
    40261 actcgataat atgataaaat cattagcagt tggaatcgca aatatatgtt atgtaataaa
    40321 tccagaagtg gtaattttag gtggtgggat tatggcacaa gaaaagttcc taaaaccaaa
    40381 aatagacaaa gcattaaagg aggttcttat agagagagtt tacaaaaaca ctaatataga
    40441 atttgcaaag agacaaaatg atgcaggaat gcttggagca ttatataatt ttttaaacaa
    40501 aatataaaga atagaagggt ttttaatgag tattttagaa caattggaat caccaacttt
    40561 taaagtcaca aaatcagata aattattaat agcttatata aaagaaaata tagatgatgt
    40621 attttataaa ccaatatcac aaatagctaa agagagcaat attggtgaag caactataac
    40681 taggtttgta aaaaaaatga attttaatgg attacaggat tttaaagtta ctttagcaca
    40741 agaaatatca actatcaata aaaaaaatat tataaataaa aatatacaaa atgatgagcc
    40801 agctttggat acagcaaaaa aacttttaag ttcaaatgta accactttag agaacacagt
    40861 agagataatc aatagtaagg atgtacatga ctgcgcaagg cttataataa atgcaaagaa
    40921 agtttacttc ataggtattg gatattctgg tataatagca caggattcaa actataaatt
    40981 tatgagaata ggtcttaatt gtgtaagttt tgacagtagt catacaatga taatgatgtc
    41041 ttccataatg gaagaaggag atttaataat tgcaatttca cattctggtg aaacagaaga
    41101 gattataaaa actgtaaagc ttgcaagagc caataatgct aaaattatat caattactga
    41161 aaataaaaat tctgaattaa aggatatttc agatgtacac ttatcttatg tatcgggaga
    41221 aacagtactg gaaactggtt caatatcttc taaattagca caatttttca ttattgattt
    41281 agtatataca caggtagtaa aagaactttc taatgaagct attgaaagga aaattaaaac
    41341 tacaaatgct ataaaattgt ttaaaaatga ataaaataag aaatttgtaa tgttttatag
    41401 agctctctta aaaatttagg aatggagaga tattacatgt ctaaattaaa agattataat
    41461 attgataaag taataatttt taataattta agtactaaaa cgaagaatca acttaaagaa
    41521 aaagttaaac taaaaagatt acaaaaaaaa gaaattttat tttatgaaaa agatagctta
    41581 gacagtgttt atatactttt agaaggaaag gtatctattt ttaagataag tgaaaatgga
    41641 gagagaaaag taattttcat attaaatagt ggggaagtca taaatgatat tacacttgac
    41701 gcttctaaaa actctactgt tggctgtgaa gcatttgaaa attcaattgt agcttattat
    41761 agtattgaag aatttttaga aattatgcaa aatgattttc aacttacaaa ggatattatt
    41821 tcttatatgg aaagaagaat aagacgttta tatagacagt tgaaaaattc tatatccata
    41881 aaagtagata aaaaacttgc agcaaaatta tataggttaa gtagagaatt tggagtttgc
    41941 tgtggagaat ggactttact aaatgtaaat attacagtta catatttagc tgatatgctt
    42001 ggctgtaaaa gggagactgt ttccagaatg ataaaggtat tgcaaaaaga agaacttatt
    42061 aaaattgaca ataaaggttt ttatgttaaa gaaactgaat tatcaaggta ttttaaaaat
    42121 aattaattat gattaagtaa gagtattatt agaattttaa ttaaataaaa atattattaa
    42181 gagaatctat ttatagattc ttttttattg tctaatttat taatttttat tttaccctat
    42241 tgaattgtat aaaaaaacaa ataagattct tttttattca aaaaattgag tagatagtag
    42301 ttttattgta cttaatgatt gtatttaagt gattagattt gaaatcgaat aatgtagata
    42361 ataaaaaaat attaacagaa cttaataaac tccattaata ttttttttat tatttttgaa
    42421 actgtgataa ttatcacgga agcatagaaa ataaagtgtt aagatttaaa caagatagca
    42481 agtaagtaaa actaaaatat aagaaaggtg ataaaaatga aactaaaatt agattcatct
    42541 aagttcaatg aaggtctgaa ttatctaaaa aaagactaca agatatttgc accagtttta
    42601 atcccattta aaggtacttt ttcagatact gatgttataa gatacaagga ggtaaacgct
    42661 tttgaagaaa tggaatttgc taagaaagca aacttttcac caaaagaagt tgtacttccc
    42721 ataaatcaag tattgtttta ttttactgaa aaagagttta aggaaagcga tttagacaac
    42781 aagaaaattt taattttctt aagagcttgt gacataaatg gtataaaaag acttgatgaa
    42841 atatatctaa ataatggtga agaaaaagat tatttttata aaaatatcag agataaagta
    42901 aagtttgcac ttgtagggtg taaggaaagt tttagaaact gtttttgtgt gagcatggat
    42961 tctaacaaaa ctgataatta ttcaattgga ttaaatatag aaggagatac actgtactta
    43021 gatataaagg atagtgaatt tgaagtattt aatggagaag caactgaatt taatgttgat
    43081 tatgtaactg ataatttaat atctgtagat gtgccagaga atattgattc aaatgaaatg
    43141 ataggaaatt caatatggga tgaatatgat acaagatgta taggatgtgg tagatgtaat
    43201 tttgtatgtc caacatgttc atgttttaca atgcaggata ttttctataa ggaaaacgaa
    43261 aatgtaggtg agagaagaag ggtttgggct tcttgtcaag tagatggata tacagatata
    43321 gcaggtggaa attcttttag aaaaaaacaa ggcgaaagaa tgagatttaa aactatgcat
    43381 aaaatacatg attttaaaaa aagattcgga tatcatatgt gtgttggctg tggaagatgt
    43441 gatgatgcct gtccgcaata catatcattt tcaaagtgta tagaaaaaat aaatgattta
    43501 gtaattagta aggaggaagt ataaatgaac ccatatatac cagtaagtgc aaaaatacta
    43561 gatatagtta aacatactga taaagaatgg acttttagag taaactgcaa tacaaaaggt
    43621 gtattgcctg gaaagtttta tgagatatct atacctaaat acggtgaaag tccaatatca
    43681 gtatcaggat atggagagga ttatattgac tttacaataa gaaatgtagg aaaagtaact
    43741 agcgagttgt ttaattataa agaaggagat tcttttttta taagaggtcc ttatggaaat
    43801 ggatttgatg tatcccttta tgaaggaaga gaaattgtag tagtggcagg aggaagtgca
    43861 ttagcccctg taagaggaat agttgaatat ttttataata ataaagaaaa atgcgaaaag
    43921 tttaaattaa tagtaggatt taaatcacca aaagatattt tatttgcaga tgatttaaag
    43981 agatggagta aaaaacttga tattttagtt actgtagatg gagcagagga aggatatagt
    44041 ggtaatgtag gattagtaac aaaatacata ccagaattgg atatgaaaga tataaacaat
    44101 acttctatag ttgtagttgg acctccaatg atgatgaaat ttacagtaga agaattttta
    44161 aaaagagatt tagatgaaaa gaacatttgg gtttcttatg aaagaaaaat gtgttgtgga
    44221 ataggtaaat gtggacattg taaaatggat gatacttaca tatgtttaga tggaccagta
    44281 tttgattatt catatgctaa aaatcttatt gattaggggg tgaagtttgt gataagagat
    44341 ttaaatacca aaaaagtaat gaaaaatgct tatagaatta caaaaacaaa atatgagact
    44401 tctttaagag ttagagtacc tggaggtctt attgaccctg agagtttagc tgtagtttct
    44461 aaaattgcaa gtgagtacgg caatggacag gtgcacataa ctacaagaca ggggtttgaa
    44521 atattaggaa taaatatgga agatatggaa gaaataaata aaattataca acctgttatt
    44581 gaaaaaatga atataaatca aagtgagaaa aacgcaggtt atccagcagc aggtacaaga
    44641 aatatagcag cttgtatagg aaataaagtc tgtccaaagg ctcaatataa tacaactgaa
    44701 tttgctaaaa gaatagaaaa agctatattt ccaaatgatt tacattttaa agtggcttta
    44761 actggttgtc caaatgattg tataaaagct agaatgaatg actttggaat tattggtatg
    44821 gctttaccaa tatatgaaaa ggatagatgt gtaaattgtg gagcatgtgt aaaaaaatgt
    44881 tctaagatat ctgttggagc attaaaaaca gaaaataata aggtggtaag agataaagat
    44941 aagtgtatag gctgtggaga gtgtgtgcta aattgcccaa caaatgcatg gactagagat
    45001 gagaaaaaat actatagatt agctataatg ggtagaacag gaaagaaaaa ccctagacta
    45061 gcagaagatt ttcttttatg ggtagatgag gacagcataa taaagataat acttaatact
    45121 tatagatatg tagaaaagta tatagataaa gatgcaccag gaggaaaaga acatatagga
    45181 tatataattg atagaacagg atttatggaa tttaaaaaat gggcacttga aggtgtagag
    45241 cttccagaaa taactaaaat gtacgaaaac atatactgga gtggaattaa atatctataa
    45301 attgagtaaa acatatattt gaataaatta aaatttaata gaaggaagag ggaattatgc
    45361 ataaagaaac tttggataaa ttaactaatg cagctataaa taagataaat ttattaaaca
    45421 caagtaaagt aaaatatttg gtatcttctg cgtttgcagg actttatgta ggtataggta
    45481 tacttttgat atttactatt ggaggacttt tgactgatgc aggttcacct atgactaaga
    45541 tagtaatggg gttatcattt gcaatagcac taagtttggt tataatgacg ggaacagagt
    45601 tatttactgg aaacaatatg gttatgtctg ctggtatgtt aaataaaggt gtaagtataa
    45661 aagatacttc taaaatatgg gcatacagtt gggtaggtaa tttaatcgga gctttggttt
    45721 taggcattat atttgtagga actggtctaa tagacaaagg acctgtagct gaattttttg
    45781 caaatacagc agctagtaaa gcatccatgc catttacagc tcttttcttt agagggattt
    45841 tatgtaatat tctagtatgt gtatcagtgt tgtgttcgtt tagaactaat agtgatactg
    45901 caaaaataat tatgatattc ttatgtttat ttgcttttat aacatcaggc tttgagcata
    45961 gtgtagcaaa tatgacaatt tatagtgttt cattattttc accaacaata aatacagtta
    46021 ctattggagg agctatttat aatttagtag ctgtaacact tggaaatatt gttggaggag
    46081 ctttatttat gggtcttgga acttatatat taggtaaaga aaagcttaat taaatttatt
    46141 gtataaatta taactctctt gataaatgca tttttagtat tgttgagaga gttattttta
    46201 tatttttgaa aaaatatttg aaacaaaaaa aatatgggag catacgaaaa tatatcggtt
    46261 atatatataa aaaatacgtt tatatatgaa ttatatagtt ctaaatataa aaaaagttaa
    46321 agtcctaccg taaaaaagcg cattttgaat aagataacaa atatgataaa attggtcttg
    46381 ttgaaatttt taggggggat atgatgacaa agaaactagt aatatcaaaa acaaagttgt
    46441 ttatttttat aatagcattt atttctatat ttatatattt atttggaagt aaaaatacac
    46501 ttataggtgt aggtatagta acagctatgc taacgctctt ggaaagagat ttaactattt
    46561 ctccaattaa aaatttactg aagtatttag caataaatat aatcttagga atactatcat
    46621 tttttgcagt acaaaatatg tatttaggag ttttattaaa ttttatagca ttatttataa
    46681 tagggtatgt atttagttat gacttaaaaa gagcagtata tgtacccttt ggtctaatgt
    46741 atatatttat ggtaagtata cctgtaggaa aaagtgaatt tcctatgaga ttgtcggctt
    46801 tagctgttgg agcagttata ataatgattg ctcaatttgt tatgaataga aataggatga
    46861 aaaatgtcgg agataaagaa ctgatatcta tatgtgatga attattagaa aaaattagtc
    46921 ttttaaaaaa tactattaat gatgatagtt ctataattaa atctagtatg agaaaaatag
    46981 atagctgtaa ttatagaata aattctatat ctaaaaattt gaaaatggtt atttttgata
    47041 atagaaaaga tgacttttat atcagtatta gaggtataga cataatgaat attttatttt
    47101 cattagaaag aataagttta atcctagaaa gatacaaaaa ggatagtaaa gaatttgaag
    47161 atgaagatat aaaaaatatt ttagaagaaa gtagcataaa tagtaaatca gatgttctag
    47221 ttgtagcaac gaaagaaata aactatatta agatgtgttt agaaaataaa gataccataa
    47281 ctgataaaga gatattagga tttagagatt atgttattgc tcaggatact aaaaatataa
    47341 atttaaaaga aatttatagt gttttagaaa atttatatga gtttttagta gattataaaa
    47401 aagtaaaatc aagagacgaa aagaaagctg aaagaaaatc aaagatacct catgaattta
    47461 aacgactatc aatatataag aaaaacttta atttaaattc tataagattt tcttatgcag
    47521 taaagattgc tttagctaca gctgtagcgg gttttattat ggattatttc catttaagag
    47581 atggaagatg gataatgtta actgtctttt cattaacaca accttacgca gaaaattgta
    47641 tacaaaggtc tagaaaaaga atagaaggta catttatagg agctgtaata tttattgtat
    47701 tattttcaat aataaaagat agtacattaa ggtcgttaat agttctttta gcagggtata
    47761 taaactctta tgtagttgat tatagaaaat taatggtatg tgtaactgtt tcagctcttg
    47821 gttcagcagt agttatggga gacccaaatg ttttaaccat aagcaggatt tcatatgtag
    47881 cattaggagc aattattgca ttaatagtaa ataagtttat attaccatat gatgctaaaa
    47941 caggctatca acatgttata gaaatgtata aaggaatagt taaaaatata attgatgaag
    48001 tcaataagtc tatagaaaat gtagctgatg tttactatat aaaaaattta ttattgatac
    48061 catcacttat tgaagataga cttatgttga taaatgctat atataaagat aaacatcaag
    48121 aggatttttt agaaaatcag aaattactaa taagtaatat gtataatcta tatataaatg
    48181 ttaataaaaa taaaataaaa gatgaagatg ttgaaaaaat attgagagat actaattata
    48241 tttcaaatta caatgtagat aagtatgatg aaggaagaag tgtaatttta gagagtatta
    48301 taaatactaa aagtctaggt gacaagataa tatgtctaaa cttactgcaa actctaaatg
    48361 gtgtcaaaga aatgtataga ataagtaata taactaaagt ttcaataaaa gaagcagctt
    48421 agatattaaa ttatagaata gccatatatt taaaataaag tatatggcta tttgttttat
    48481 aaaatactaa aagaaaataa tatataaaaa acaaaaaaca tatatttatg aattttatat
    48541 gaaaatagtt aaaatattga tttttttcat tggttgaaaa aacaatttac ttaggataaa
    48601 ctataatagt attcaaatat tatgggggtt agatttatga gtaaagatgt aaaggtaaag
    48661 cgtaataaga aatatgatac atttagtata actatggaac ttgagagacc tttactttat
    48721 gatgaggttg agaacaaaga tgataaaaat aataatagaa aatttaacat aaagaataag
    48781 atatttaagg gaataggtat actatttgta ttgattttgc ttggcttttt catatggata
    48841 aataaaacat atgaacctca aaagctggca aaagaagctc tagtcagcaa tagtaaagtt
    48901 gaagtaactg taaatgaaaa catttcattt acaccaaaag gaagaaaagt ttctaaaggt
    48961 ttaattttgt atccaggagc taaagtagaa atagaatctt atgctccact tgcaagaaaa
    49021 atagcagaaa gtggatatga agttgtaatc gtaaagatgc cacttaatct agctatactt
    49081 ggaactaata aggcacagaa agttatggat tcttacaaca acatagaaca ttgggtaata
    49141 ggaggtcatt cattaggagg agttgcagca tcaaattttg cacgtgataa taaattaatt
    49201 gaaggcgttg tatttttagc ttcttatcca atgggtgatg agttgaaaga attaggaaaa
    49261 aaagttatat ctatatgggg gagcaaagat ggagtagtca attttaaaag tcttgtagaa
    49321 tcaaaacaaa aacttcctga tgatacaact tatgttgaga ttgaaggagg aaatcatgca
    49381 caatttggag attatggaaa acaaaaggga gataatgatg ctattataag tcaagaaaaa
    49441 caacttaata ttactgccaa tagtatcatt aaatttttaa agaatatatc ttaaactaaa
    49501 atttaaaaaa tataatttta taagttatta tttaaagtaa atattaataa tataatagaa
    49561 tgaatatttt attacaaggg ggattttaat atggaatacg atatgccact ttacagacca
    49621 ccaagtgagg cttatagtct tataatacaa gtcacactag gatgttctca taacaaatgt
    49681 acgttttgta gtatgtacaa atctaaaaaa tttaaaataa agccactaga agtaataaaa
    49741 aatgaaattg atatatttag aagatattat aagcatgtag aaagaatatt cttagcagat
    49801 ggagatgcat tgataatacc aatggagaaa ttaagagata ttattttata tataaaagaa
    49861 gtttttccag agtgtgaaag aattactatg tacggctctc ctaaatctat agagaaaaaa
    49921 tctgatgatg aacttaaaga attaagaaaa cttggtgtta aaatgattta tctagggctt
    49981 gaaagtggaa gcaatgaagt attagaagat attaagaaag gttttagtag tgaacaatta
    50041 ataaaagttg gtagaaaagt taaaaaaagt gggattaaat tatcagccac tgtaatagca
    50101 ggtcttggag gaactaaaaa aacacatcag catgcagttg atacaggaaa aatgctagga
    50161 gcaatttcac cagattatgt gggtgtactt agtttaatgg tagaacctaa tactgaactt
    50221 tacgatttac ttaaggcagg agagtttaca atactagagg ataaggctgt gttacaagaa
    50281 attaaagaga tgataaagaa tatagatgct aatgaaaaaa ttgtatttag aagtaatcat
    50341 gcatcaaatt atgctaattt aaaaggtgta ttacctgatg ataaacaacg tctaattgat
    50401 gaaattgatt actatctaag taaccaaaag ctaaaaagag aagaatatag aagactatag
    50461 tttttgatat atcaatctat actgataggt aaatactaag attatttaga tacaaaaaat
    50521 catgctacat taatagttgc ttactattga tgtagcatga ttttttatta aaaaacaaaa
    50581 tggtatattc atatataata tatcaataat aatgaaaatg tgaactagtt taatagaatt
    50641 ttacctatta taataaaaac aggaatttaa ataataaaaa gtaaagtaac tttttattaa
    50701 gtaactttac tttttatttt atttaatgtt gtattaaatt tatatatatt aaaataatat
    50761 acaaattttg aaaaagctct tataaaatga ttattaaagt aaagttt
//
LOCUS       DAEHWO010000020        49778 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEHWO010000020 DAEHWO010000000
VERSION     DAEHWO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49778
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.020"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            130..804
                     /locus_tag="KNP54_001428"
     CDS             130..804
                     /locus_tag="KNP54_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892334.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            792..1952
                     /locus_tag="KNP54_001429"
     CDS             792..1952
                     /locus_tag="KNP54_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBF0892335.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            2168..2695
                     /locus_tag="KNP54_001430"
     CDS             2168..2695
                     /locus_tag="KNP54_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBF0892336.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFSSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            2981..3649
                     /locus_tag="KNP54_001431"
     CDS             2981..3649
                     /locus_tag="KNP54_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892337.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            3652..6120
                     /locus_tag="KNP54_001432"
     CDS             3652..6120
                     /locus_tag="KNP54_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892338.1"
                     /translation="MKNYLSLSIKELKSQKFMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYIFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(6360..7784)
                     /locus_tag="KNP54_001433"
     CDS             complement(6360..7784)
                     /locus_tag="KNP54_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0892339.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(7803..8495)
                     /locus_tag="KNP54_001434"
     CDS             complement(7803..8495)
                     /locus_tag="KNP54_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892340.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(8547..9326)
                     /locus_tag="KNP54_001435"
     CDS             complement(8547..9326)
                     /locus_tag="KNP54_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBF0892341.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(9323..10093)
                     /locus_tag="KNP54_001436"
     CDS             complement(9323..10093)
                     /locus_tag="KNP54_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBF0892342.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(10090..10794)
                     /locus_tag="KNP54_001437"
     CDS             complement(10090..10794)
                     /locus_tag="KNP54_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBF0892343.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(11049..11561)
                     /locus_tag="KNP54_001438"
     CDS             complement(11049..11561)
                     /locus_tag="KNP54_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892344.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSDCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            11887..12144
                     /locus_tag="KNP54_001439"
     CDS             11887..12144
                     /locus_tag="KNP54_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892345.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            12287..12913
                     /locus_tag="KNP54_001440"
     CDS             12287..12913
                     /locus_tag="KNP54_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBF0892346.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(13160..13939)
                     /locus_tag="KNP54_001441"
     CDS             complement(13160..13939)
                     /locus_tag="KNP54_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBF0892347.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(14007..14468)
                     /locus_tag="KNP54_001442"
     CDS             complement(14007..14468)
                     /locus_tag="KNP54_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0892348.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(14444..15121)
                     /locus_tag="KNP54_001443"
     CDS             complement(14444..15121)
                     /locus_tag="KNP54_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0892349.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            15354..15740
                     /locus_tag="KNP54_001444"
     CDS             15354..15740
                     /locus_tag="KNP54_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0892350.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            15743..17542
                     /locus_tag="KNP54_001445"
     CDS             15743..17542
                     /locus_tag="KNP54_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBF0892351.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(17897..19771)
                     /locus_tag="KNP54_001446"
     CDS             complement(17897..19771)
                     /locus_tag="KNP54_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0892352.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLASIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(19776..21440)
                     /locus_tag="KNP54_001447"
     CDS             complement(19776..21440)
                     /locus_tag="KNP54_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBF0892353.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(21454..22275)
                     /locus_tag="KNP54_001448"
     CDS             complement(21454..22275)
                     /locus_tag="KNP54_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBF0892354.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKNREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(22374..23138)
                     /locus_tag="KNP54_001449"
     CDS             complement(22374..23138)
                     /locus_tag="KNP54_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0892355.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(23135..23884)
                     /locus_tag="KNP54_001450"
     CDS             complement(23135..23884)
                     /locus_tag="KNP54_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0892356.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(24388..24993)
                     /locus_tag="KNP54_001451"
     CDS             complement(24388..24993)
                     /locus_tag="KNP54_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0892357.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            25172..25810
                     /locus_tag="KNP54_001452"
     CDS             25172..25810
                     /locus_tag="KNP54_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0892358.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            25942..26604
                     /locus_tag="KNP54_001453"
     CDS             25942..26604
                     /locus_tag="KNP54_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892359.1"
                     /translation="MAKILLLEDNDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            26604..27785
                     /locus_tag="KNP54_001454"
     CDS             26604..27785
                     /locus_tag="KNP54_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0892360.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(27966..30626)
                     /locus_tag="KNP54_001455"
     CDS             complement(27966..30626)
                     /locus_tag="KNP54_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892361.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(30623..31306)
                     /locus_tag="KNP54_001456"
     CDS             complement(30623..31306)
                     /locus_tag="KNP54_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892362.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(31650..32603)
                     /gene="blaCDD"
                     /locus_tag="KNP54_001457"
     CDS             complement(31650..32603)
                     /gene="blaCDD"
                     /locus_tag="KNP54_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBF0892363.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(33144..35258)
                     /locus_tag="KNP54_001458"
     CDS             complement(33144..35258)
                     /locus_tag="KNP54_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBF0892364.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMATKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHVVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REKYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(35516..36376)
                     /locus_tag="KNP54_001459"
     CDS             complement(35516..36376)
                     /locus_tag="KNP54_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892365.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            complement(36971..37333)
                     /locus_tag="KNP54_001460"
     CDS             complement(36971..37333)
                     /locus_tag="KNP54_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBF0892366.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(37567..38031)
                     /locus_tag="KNP54_001461"
     CDS             complement(37567..38031)
                     /locus_tag="KNP54_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBF0892367.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(38460..39881)
                     /gene="nhaC"
                     /locus_tag="KNP54_001462"
     CDS             complement(38460..39881)
                     /gene="nhaC"
                     /locus_tag="KNP54_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBF0892368.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(39911..40975)
                     /locus_tag="KNP54_001463"
     CDS             complement(39911..40975)
                     /locus_tag="KNP54_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBF0892369.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(40960..42369)
                     /locus_tag="KNP54_001464"
     CDS             complement(40960..42369)
                     /locus_tag="KNP54_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBF0892370.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(42369..44573)
                     /locus_tag="KNP54_001465"
     CDS             complement(42369..44573)
                     /locus_tag="KNP54_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBF0892371.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(44567..44941)
                     /locus_tag="KNP54_001466"
     CDS             complement(44567..44941)
                     /locus_tag="KNP54_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBF0892372.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(45019..46449)
                     /locus_tag="KNP54_001467"
     CDS             complement(45019..46449)
                     /locus_tag="KNP54_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBF0892373.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSYFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(46442..46750)
                     /locus_tag="KNP54_001468"
     CDS             complement(46442..46750)
                     /locus_tag="KNP54_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBF0892374.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(46894..47961)
                     /locus_tag="KNP54_001469"
     CDS             complement(46894..47961)
                     /locus_tag="KNP54_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBF0892375.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     NVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTIVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(48217..49590)
                     /locus_tag="KNP54_001470"
     CDS             complement(48217..49590)
                     /locus_tag="KNP54_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0892376.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGREITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRKNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
BASE COUNT        16883 a         8387 c         5911 g        18597 t
ORIGIN      
        1 ttaatatata aaaatatact aactttaatg attaagtttt gaaatataac taagaatttg
       61 ataatttatt gagattttta tactaaaata tacatactat acaaacttaa tttagaaggg
      121 agcattctta tgaacaataa aatactcgtc gtagatgatg aggaaggtat aataacactc
      181 ttaaaagatt actttgaaat gaatggttat gaggtttaca ctgctcaaag tggaaaagac
      241 gcattaaaaa aaatatctaa aaatccagat atcattctac ttgatataaa catgcctgaa
      301 atagatggaa ttgaagtttg taatagaatt agagattatg tatcatgccc tattctattt
      361 cttacagcta gaattgaaaa tactgacaag ataaatggtt ttcgtgctgg tgctgatgat
      421 tatattgtaa aaccttttga tttagacgaa cttggagcta gagtatctgc ccatttaaga
      481 cgtgaacaaa ggaagtcaaa tcaaactaaa attaaatttt ataatgattt aacaatagat
      541 tacgaaaaaa ggttaatttg tatatataat aatcagattt cactttcaaa aaaggaattt
      601 gatatagtag agcttctctc tatgaatcct ggacaagtat ttgataaaga aaaaatatat
      661 gatagagtct ggggatacaa tagcaatgga aatagtgatg ttataatgga acacattaga
      721 aaaatacgaa tcaaactatc aaaacatact cttgaaaatt atatagaaac agtctgggga
      781 gttggttata aatggataaa ataaataata tgtcattaaa aaaagctttc tttgttctta
      841 ctttatcttc actaattata gcatcagtgc ttactacttt cgcatacatt ttacttaata
      901 atctatataa ttctatacaa gataagtatt taaaaacacc tataaataca ggtattataa
      961 ccatagttca aaacaatgtg aaccaattta gtgattatga taaaacatta cttaatataa
     1021 tcaacatact tcagcttgta cttccactta tcttttttat aggactttta ttattagctg
     1081 atataatttt ttacaaggta aaattaaaaa cacccataga aatactcaat aaaggtgcaa
     1141 tggaaatatc caacaacaat ttagactttt gcttagaata taataataat gatgaattag
     1201 gtaatctatg taatgctttt gaaaaaatga ggtctgaact aaataaaaac aacataaaga
     1261 tgtggactat gattaatgat agaaaacaac ttaatgctgc tttttctcat gatttaagaa
     1321 atcccctaac agttctaaaa ggttactcaa actatttaac aaaatacata ccaacaggta
     1381 agcttagtga tgagaagatt ttatcaacca cacaacttat gtctgagcat attaacagaa
     1441 ttgaatacta tgtagaaaat atgagtaatg ctcaacgatt agaagattta gttgtttcaa
     1501 aatctatgtc gaatataaac aagtttatag aaaacttaga tgaaaatata tctatcattg
     1561 ctaaacaaga aggaaaatct tttacactta aaagtcaaat aaataatata aatctatttt
     1621 ttgatgaaaa tatcattctt agagtcgtcg aaaatataat atcgaatgct tttagatatg
     1681 ctagaaataa tgtatccata cttatatatc ttgaacaaga actccttacc tttgtaattg
     1741 aagatgatgg tataggattt agtaaggaat ctctaaaatt agctttaaga cctttctata
     1801 gagataagac tttaaatgac agcaatgcac actttggtat gggtctttat atctcaaaaa
     1861 tattatgcga aaaacatggt ggctctattt ctattgaaaa taattctact aacagtgcta
     1921 aaattactgc taaattctca acaagaaatt aaaatgattt tgtaagcttt cactgttctt
     1981 atataaaatt tgttagttta gaatttataa aatgtatttc aatttacaac caatatatat
     2041 actattttgt agaagttgta agagttgctt caattataat atttggcaaa aggcatttga
     2101 aataataata gaaatatata tttaaatatg tagaatagta tgaaattaga attttggagg
     2161 tgattatatt aaaagttttg ctaataatat tacattctct cgtattgtgt ttgcattgct
     2221 aatgcttagt tctacattct cttcactgcc tttctggata tgttattttt ggtgtggaat
     2281 tagtgatata cttgatggtc ttattgcccg aaagttgaga caacaaagtg gaataggtgc
     2341 aaagttagat agtattgctg atttcatttt tgcggttaca attttggtta ctgtcggaaa
     2401 aaatattgct cttcccatgt atctatggtg gtgtattgtt gcaatagcat tgttacggtt
     2461 gattagttac agtattggtt tttttaagta tcgcacattt tcatcgcttc atactttgat
     2521 gaataaaatc actggaattt ctatctttgc ttttccatta ctctatattt gctttggtct
     2581 tgatgttgca ggaattatga tatgtatcgt ggcttttctt tcttcttttg aagaaatagc
     2641 aattatgata aaatcaaaag aattaaatcg tgatataaaa agtatattta tgtgacaact
     2701 tagaatttgt gacaaaaata atttatataa taatgaggaa gtaaaacata aaaaattatc
     2761 cacaagttta tgtgtaaaat agttttaaag caatagagtt gtattgtaaa gcctttagtg
     2821 cataaattac attttaaatt aaaaatgata ctgaaactgc ttatcagcac tgcgaattat
     2881 ccgcaaatag tgaagacttt ttagatttaa gctaaaagtt gggaaaaaat tgagttttaa
     2941 aacttacact cttcttatat agaaaaggag agtgtttttt atgattataa aagcaaaaca
     3001 attatcaaaa atatatggtt ctaataacaa taaagttata gcacttaata atgtaaattt
     3061 agaaataaac tcaggtgaat ttgtttctgt aattggacct tctggaagtg gaaaaagcac
     3121 acttttgcat attttaagtg gattagataa tcctacctct ggacaagtgt tacttgatga
     3181 taaagatata tataaacaca ctgaaaaaga actatctgca cttagaagaa aatcctttgg
     3241 attcgtcttt caacaattta atcttttacc tgttcttaca gcatctgaaa atatttcaat
     3301 gcctgtactt ctagataaaa aacaacctga taaagactat ttaaatgaaa tttcatcatt
     3361 acttggaatt gcagatagac tcaatcatct tccccatgaa ctttcaggcg gtcagcaaca
     3421 aagagttgca attgctagag cacttattgc aaaaccagat ataatatttg ctgatgagcc
     3481 tacaggaaac ttggacagta aaagtggcag tgaagttatg aatcttctta taaaaacttc
     3541 aaaacagttt ggaaagactt tagtggtaat tactcatgat gatagaattg caaaacttgc
     3601 tgatagaaaa atttcaatta ttgatggtgt tcttatggag gtgaaataga aatgaagaat
     3661 tacctttcac tttcaataaa agaattaaaa agccagaaat ttatgactac attcatcatt
     3721 atagcaatag tactatcaac tattatgaca actgtggttg gacagtcaat tggtatccta
     3781 caaaatttaa gaattgaaca agcccgttct tttaatggtg atagacatgt atcctttcac
     3841 caactcacta aaaatcaagt tgatgacata aagaaagatg atagagttta tcaagctggt
     3901 acttcaataa ctattggcag tagtaaaata aaggattctg gtatctctgt acttgtaaaa
     3961 gagtatgata aaacaggact ttctaactac ccaaaattaa tgaaattaaa atctggacat
     4021 ttgcctaaag ataaaaacga aatagcctta gatgaaaaca cactaaagct tatgggtata
     4081 aaaccaagac taggagtgac tatacctatg aatttagata tttcactttt aaatgatacc
     4141 ataccaccat ataattacac agctaacttt aaattgagtg gcattttaga ggatgattat
     4201 acaggatatg taagtggtat agtaaatggt attgtaggta aaggtacatc agaaaatcta
     4261 ttacctaaga gatatatttt atcctctttg gattttaaaa taaaacagca agaaaagttt
     4321 caagaaatag taaatcaatt agctaaaaaa ataaatcttt ctcacaattc aattcaatat
     4381 aattggattt acttaaatgc tcttaagata cagtttgaaa aagatgaaaa tagttctaat
     4441 agtgatggta tatctatgat tatattggta tctttatttg ttgccttatt ggttttactg
     4501 gcttctggac ttgtaattta taatatttta aaaatctctg ttacaaagaa aattaaagag
     4561 tatggatgtt taagagcaat aggagctgaa ccaaaccaga tatataagat agttatttta
     4621 caaatcttaa ttttatgtac tgttgccata cctattggag ctgtaattgg aattatatct
     4681 tctaaaggca taactggaat ggtcactaat atcttaaatc cagatatact tctagcaaat
     4741 gataataaag aaattactga gcttatacat aaaaatacaa cagcatatat attcccatta
     4801 gtattaagca ctaatgtatc tttgattttt tcatttattt cagcattacc atcagcaata
     4861 tatgcttcac atgtctctcc caaaattgct atggttggta gtactaccaa aatcaaaaga
     4921 aaaattaaaa gagaaaaaac aataaaaaac tttgaaagac atctagcatg gctaaactta
     4981 aaaagaaata aaggaagaac tataataact atactatcat tatttatgag tataacagta
     5041 ttcgttgcac tgagtgagtt ctctaatgta ttagatgtat ctaggtcagt aagtaattta
     5101 aaagaaggag atttttcctt aacaaatgaa atatctggtt ttgataaatc aacactagat
     5161 aaaatagcta aaatgaaaaa cgtcaatcgc acttccttta taaagtactc tgaatacaaa
     5221 cagggtgaaa tagatacaga tataaatttt gaaaatagtg gtgagatgtt aaaaatcatt
     5281 ggaattgatg agcaaacttt aaaagactta atgccttcta ttacagattc tatactagaa
     5341 gactttaaaa atggttctat ctgttttata aaaaatccga ttgctatttc tacaccaggt
     5401 gtaaaaacta gatatacaaa tttaaaacct aaagatagta tcacaatcaa caaaaaacaa
     5461 ctagatatat atagtacagt agataaaatg ttctttttac aaggcaatgg ctggataaat
     5521 ggtgttgatg ttattgtata tgattctgtt tataacactt tgacaaataa aaacaagttc
     5581 aaccagataa atatttatgc taaagataaa tcaaaattag aacaaataag attgtctatt
     5641 gaacagattt gtgaaaataa tcctggctct cattggatat catatattga atcagataaa
     5701 caacttaaag agagttttaa acaaatagaa tttctagcat gggcagttat attatttgtg
     5761 ggattgattg gtactttaaa catcattaac acaactcata caaatataaa tactaggact
     5821 aatgagattg gagttaaaag agctattggt atgagtaata ggagcttata taaaatgttt
     5881 ttatgggaag gtgtttatta tggaattttt gctgctatat ttggttcaat tgctgggtat
     5941 gccagtgcta ttatcataaa catggcaact atagaaaagc ttgatttcac taatatacca
     6001 attacttcaa ttttacaagc tactattatt tctgtacttg catgtattat agctactctt
     6061 attccgttaa gaaaagttaa aaagatgaat ataattgact gtatagatat caatttataa
     6121 ctattttaca gataataata taaattaaat tatcaatgac tgtctctatt ttctttcaaa
     6181 tctaactaat aaatcttttt aactataata taagctttaa aaaaggcctg tctcaaaata
     6241 gagataagcc ttttttcatt gtcgaaataa tgaaaatata tttaacttca caaaaaaaga
     6301 gtgcctcacg aattaaaaat ttcgctttga gacactctcc tttaatttaa aatatatagt
     6361 taaatgctat gccaaaattt cacacatgct ccacctgatt ttgaattttc tattttaaca
     6421 gaacctccaa gctgttccac taattgtttg acaatgtaaa gcccaagacc agaatgtcca
     6481 ccttttgtct gcctagcttc atctcctcga taaaatttat caagagcctt ttttaaatct
     6541 ttagagctaa accctctacc agaatcacaa atctcataag aaatacaatt tttttcatcc
     6601 tttacagtaa tactaatatt accacctgat ggagtgtatt gcagactgtt ggatatgata
     6661 ttatcaaaaa ttcgtgtcaa cctatcaacg tcgatttgaa ttggggattg tatattcccc
     6721 tgcattttca atataagttc aacttccttt tgatgagcct gtaattcata gtcttgcacc
     6781 ttttgcctca aaaattcagg taaatttata ggaacaagat ttaattgtat atttgacttt
     6841 tctaagtcag acgtatattg catcttttgg acaagagcag cacttttttc tgtattttct
     6901 cttatcactg taagatacct atgaagtttt tcattgtcat ctgtattatt accaataagt
     6961 gcatctgtat atcccaaaat aatagaaaga ggagatttta aatcatgtgc tagagcttcc
     7021 accatttcaa cacgttcctg ctccatcttc cactgtgcag ataaagagcc ttttaattcg
     7081 tctttcattt cagaaaaggc actacaaagt ttaccgagtt cattatctga ataatagtcg
     7141 atttcaaaat caaggtcctt ttcttttatc ttcttggacg catcaatcaa tagatgtaat
     7201 ggttgattga tattctttac aaagcgctta gaaagccatc tagtaaaacc cacgatatat
     7261 agaaatggag aaaacaaagc cattataata actgcaaata caaatctccc tctaatattt
     7321 gcaaaggtga ttttcacttg gtagaataga ataacagcac cctcaatctt tccattatcc
     7381 cctttgattg gaacagtatg gatataacca cctttacgaa cagttttatt gataaaatta
     7441 ttaaataatt cttcttttgt tttaaatagt tttttggggt tagtaccata taaaatattg
     7501 ccattattat ccacaacttg atatagcata tcatccccac gaatcgttct ttttaaacct
     7561 tcttcattcg attgtgataa caaagctatg tttttttcat tgatgtattt ttcaattcta
     7621 ggaacttgtc gctcataata gtttggtgga tagatatcct tatttaagga atgaatatac
     7681 aaatagagag caaatacata agtaatcact gtggcaacta tactggctat tataataaaa
     7741 ataaaagtat gtctaaattg ggtaataagg gattgatttt tcatttaata acctctctct
     7801 ctttacattt tattccactt atacccaata ccccaaactg tggaaatata ttctttttct
     7861 ggtgtcacag cagaaaactt agctcgtatt ttttttactc gttcaacaac agttgaggaa
     7921 tcaccttcag aatcacaccc ccatactttt tcatagattt gttctcttga gaaaacttgt
     7981 cctgcatgga gtgctagtaa ttcaacaata tcatactcta tttttgttaa atcaatattc
     8041 ttaccatcaa ttttaattgc acgttccttc atatataagc ataacttccc aaaatacaaa
     8101 gtagatctct tgttctcttc attgatatac tgtgaacgct tttccctacg cagattagct
     8161 tcaatccttg ccataagttc acgcagtcca aatggctttg ttacataatc atcccctcca
     8221 aaggtcaacc ctttgatttt gtcggtttct gattgctttg cacttaaaaa tataattggg
     8281 cataaaacat catctctaat tgcctgacat acctcaaatc cattcatttt aggcatcata
     8341 atatccagta taataaggtc aggctcctgt tttgataact ctatacctgc ctgaccatca
     8401 taagctatca acacttcatg tccttttgcc ttcaattcat cctcaagtag cattactagg
     8461 tccatttcat catcaataat caatatttta ctcaatataa caccaccttt ctcttatggg
     8521 aaggtcagta ttaaaacaat attcgtctac tcataacttt tccttccctc ccacatttta
     8581 aaccaaataa cgcctcctat caagaatata atcaaaccta ttgctactac tataagctct
     8641 atactagctg tttgcatcac tttagagtaa aatgcctcag ttgaaatagt tccagcttct
     8701 ttaataaaat aaattcctgg aagcatacct agttttactg gccatgtcca tggaacaaat
     8761 gcccatactt tttcaccaac gctagttaat ccaagtattg ctgccatcaa aattccacca
     8821 atactaatac caatagatgc acccataccc catgcaaaac tcacccaaag atgaatagct
     8881 aatagtggaa gtgtcccaat caccacaagt cctgctgctg acaggaataa ccatattgtt
     8941 gctccagatg gcactgcaat actcattcct atgcaaagta tcaacgtagc aataaatgtg
     9001 catatagtta ggcaaaacag aagaaaaaga aattttccca gatataatct gacacgagaa
     9061 atacctacac ataaaaaacc attaaaattt ccagcaagct cttcctcctg cactataaat
     9121 cctgctaaaa tacctactcc aataggaatg atgaatacag tccatactgt aaaaaatcct
     9181 tcaaaagcaa attcttgtgt acttccagat ttagttgtga gataaaaaac cacacataat
     9241 gaaaaaataa taggcataca aagagtaagc cactggacag ctgtcctctt tgctcgaagc
     9301 cattctgatg ataatagttt tatcatttgt catccctcct attgaaccaa gctgcagtaa
     9361 gtgctgttaa tactataaac acaaccaaag aaacaacaat cccaatagga atcactgaag
     9421 tattcaaaag tgggtctcca gcttctaata tagtaccgtt aggatgtatg ttgatgattg
     9481 ggcataccat tctaactgcc caactccaag gtactgcaat ccaaaatggt tttgtcgcag
     9541 caagaacacc aaatatcata cctaaagctc caactcccat acttaggaac atacctttcc
     9601 atgtagctag ccatagctga agtggaagta tagcaagaga aacaacccag catacaatac
     9661 ttgcccctat aatctgtcca aaaggaactg gaccagcttt caatattaaa ccagttataa
     9721 ttgttacgac tattaaaact agcgttgaaa taaaactgta gactgccata gctataactt
     9781 tattaatcca aagtgtcata ggagacacat tgtgtgtacg taaagcacga taatttccag
     9841 cttttttttc ctggaaagct accaaagtag cgaacaatgc aaatccaata ggcagaaata
     9901 aaaatgacca ccagttaaaa attaatgcta aaagattttg ccacgcccaa gaagttgttt
     9961 gagataatgg attttgcatg agtgttgatt gcattataaa tgcatatgct gcaaaagaca
    10021 ctgggaaaaa aacaataagt ttacccataa atgttctttt atactttaaa agttctgatt
    10081 gtaaagcatt catctgtttt gtcctccttt aagaataaca tctgtaaaaa attcttctag
    10141 attttcatta gggtcaggca ttccttgaaa taatagtcgt cctccattta taattcctat
    10201 attatctaca acttgagcaa cctctgatag aatatggcta gaaagaatta cagttatacc
    10261 ttttttggga aaagaagcaa tcaattcacg caattcttga atgccaaagg ggtcaagacc
    10321 attggttggt tcatctagta ttaacaactc tgggtcactc aaaagtgcaa tagctattcc
    10381 taacctttgt ttcataccca tagaaaattg tgaagctctc tttttacctg tatttttcaa
    10441 atttactatt tccaacactt cataaatttt atctttaggt attcccaata tttttgtatg
    10501 tactaacaaa ttttcctctg ctgtaaggtt tccatacaat gcaggggatt ctattaaaga
    10561 acctattttt gcaagagatt ctcgtttcca aggctttcta tcaaaaataa tacgaccatt
    10621 tgttgggcga agaagaccaa caagcatttt aagtgttgtg gactttcctg ctccatttgg
    10681 tcctaaaagt ccatatatac tatttcgttc aatttgtaga gaaacattgt taactgccat
    10741 ttgttctcca tatctttttg ataagttttt tgtttcaaga attaaatctt tcatattaat
    10801 ttctcccttc ttgtaatacc ttaaatctgt tactaagaga atactaacat gaaaaaataa
    10861 caattctata acacctacta attttaataa aatttaaaat aaaaaataga gttaccaatt
    10921 ttattttggc aactctattt aagtttatgt tttacagtta tattagattt aaacttagtt
    10981 tcattatcac actaacttca aatttactct ataatcttta aatcaaacac taatttatta
    11041 atcaaacact aatctattaa tttatatttc tttagacatc taatatagtt tgctactaaa
    11101 taataattat ttatatcata tttatctaat cctttaaaag aagttatttc atcattaagc
    11161 tcatcactac cttctacaaa aacacaacct gtttcaaatt ccatacctac aataatctta
    11221 cagtcactat aaatttcctc ttgagtatcg tacaattttt ttgcatttcc ttcatttgga
    11281 attgtaaata caataggttt taattcttta tcactggaaa tcttttgtga aaaaggcttg
    11341 tttaacttaa tattattgat aactacatgt ttaaattcct ctgaagtttc ttctactatt
    11401 acatattttc gctttaaaaa ctctattatt tctaaaacag acttagaatt tacttttaaa
    11461 atacttttat atttttcata taaagatttc cactgttcaa ttttttcctg tggtatttct
    11521 tggatatgtg tacttatttt ttcttgagat atttttttca attaaactct cctttcaata
    11581 cttaaatatc cttatgaatc tcacatgact aaagttacaa ggtttctact taatagaatt
    11641 ttgcatactt aaatatgtct tattaattct ctacaggata tctccgtagt tcctacgatt
    11701 cttacataag ttacttattt taaattgtta ttagttatat tctaaaaatt atttatttta
    11761 tcactaatat aatactctta aaaactttac aaatcaattt aaatttgcta ccttttattt
    11821 ataacaactt atagtacatt tctcctatgc ttttcaatat attactttta aaaggaggtt
    11881 ttcattatga ttttaaatag agctgagctt ttccgaggat attctttaaa tagatttaac
    11941 gagatatgca atatattatc agtaaataaa attaaatata agtataaagt gaaaaataat
    12001 gcttactcta aaaaaccttt ttttaatgaa ataacacttg gcaatttagg ccaaaaggaa
    12061 gatttctctt atgagtactt aatttatgtt cataaagacg attatgaaca ggcagagtct
    12121 ctaataaatt ctaagttgcg atagattatc tataaaacat gacattctgt tgtcatgttt
    12181 tatatgttat tatactttca aatatgctac tatattttca aaattgtgtg ctttaaaact
    12241 agcttttttt agtaatttaa agcttaaaac taaggagact cgttatatga aaataaatat
    12301 aaaatcaaag ttaagtgaat ttattaaaca gaacaatctt tttgatgaca gcagaataat
    12361 atcctatctt cctaatataa caatagaaac agacaaaata aaaactataa tgattaatga
    12421 ggttgtccca actaacacca atgacgattt ttatagtgta gataaagatg ctgattattt
    12481 aaaaactact attcctttat ttgacagtgc aggaataaaa gtatctaaca taaatgatat
    12541 cctagatatg ggtatctata taactaatgc agtaaaactt cctaaatcag aatatacaat
    12601 aactcgtgat acaattaaat tacatatgcc tattttagaa gaagaaatta aattatttaa
    12661 aaacctagag gtagtaatgt taatgggaga tgttgcaaaa aaatctttta atatgattac
    12721 taaaaagcat ataaaaaaga atgtcatccc ttccatttca acatataaac ttcgtaataa
    12781 tgaactttat tatgataatt taagagtatt tccatcatat attatgactg gtggaaacat
    12841 actgattgaa aaatcaaaat ttgaaatggc atcagaagat ataaaaaaaa tgttcgagat
    12901 tataaacggt tgatattaca aaataataaa aactaatata aaataaaaag tgcctcaaaa
    12961 acttctattt atgaggcact tttattttat attagtgtaa ctatatacta ttaacataat
    13021 ttattattta tattgttctt tttaatctct attccattta gtctaggtaa cattactctt
    13081 tacaagatta ctttatattt cttttatatc tctaacgttt ttatttaata aaacaattat
    13141 taatacaagt caaatatatc tatttatcta aaaatatatc ttttacagta atatctggat
    13201 ggtgatactt cttcctattc gttaaaaaag atttttttac attaatagcc tcttttggac
    13261 accagtgaaa acaagctagg catctttcac actcattacc ccactttggc tttttatcaa
    13321 ctatacttat attctctaca ggacaaaccc ttttacatgt cccacatcca ttacatttat
    13381 tttctgcaaa aaatttagta gttgcaattt gcatattctt acctactaaa cgaagtacaa
    13441 cactatctat atgtgacttt aaattgtttt ttccttctat atttccaatc tccaagttat
    13501 tgatacattt tgcaatctca gctaccctat tagtctgatt tttcaatctt tcttcttcaa
    13561 catctggagg tgttatcaaa gcatttccag gcatattgat taaaaaacca gcagataatt
    13621 ttttccccct ttttttaagt aacttatcta tagtaaataa actatgtcca gctaccccat
    13681 tacaagtggc aatggcatat atatgagtat taatattaaa atttaatttc tctacaaaag
    13741 actttactat atcaggaaca tcagcaaaat aaacaggaaa aacaattacc aatatatctt
    13801 catttatgtc tatattattt tcttttctat gtatagctaa gggtataact tctttacttc
    13861 catttaacgt ttcttttaaa atatttgaaa ctactagcga atttcctgtt ccagaaaaat
    13921 aataaatctt actattcatt cttatccctc tttctatatt tctacatcat caatagttaa
    13981 aaagtctctt aaaataggat ttatatttac tttccaattc tatccaaaat atcagtaaac
    14041 aaaggcaatt cttcatcaga gatagattta aatgtctctg ttgcatatat acttgcaatt
    14101 tcatttaatg gttcttctaa ttctctacct aaatctgtta ggaatatttg aaacttacgt
    14161 ctatctttaa catctacttt acggacaatt aatcccttat ttttcataac atctaaaatt
    14221 cttgttgtat tagatttatc cttacatgat ttttcacata aatctatctg agaaatccca
    14281 tcttgctccc atagaaacct taataacgca taatggtcag ttgttatatc atatccattt
    14341 tgtttaaaca tcttttttaa atcatctttt acttttaacg aagtacttac taacttagtt
    14401 gtagcttcat atagtttctc aaaatctttc attttacctc catttaaata atcccttgct
    14461 cctcccatct atcaattatt cccttatatt gctcaatatc tttaaaagcc attggcttta
    14521 aaacagcatt tatagcaata aaattataga tttgagaaag cacaggtgga tttttctttt
    14581 cctctatgca ataaataaat tttttagata ccttttgtat ctttgattct actttttcag
    14641 ttataggatt ttgattaaat ccagttttta tagataaact accacaaaca taacctcccg
    14701 aatctaagac catggatttt ataaaagaaa ttgcttttga accacgtgca ttttcatatg
    14761 tagtaactgc tatacatggc ttacgataca ataatctttc aagcatcata tgtgctctat
    14821 ctgtaaacac cttgaaaagt ccagttacac tacttccata agttgggcta ccaaatataa
    14881 caccatcact cttagtaatt atatcatgaa tatactctac tttatcattt tgattgatac
    14941 acttgcccat tttataacaa tttaaacaac caatacaata tgatggattt acctcactta
    15001 aatcaaaata attaattttt acatctggta ttaatctttc tatatcttta tacaagtaag
    15061 ttaaaacttt tgatgtagct ccattttttc tagggcttcc atttataact gtaattatca
    15121 tttctatatc tcctttttag ttgttatatc aacaataagt atatcaacta taattttagc
    15181 tgtcaatata aaccatttat ttaaagctat acttacacag cttaaataaa agttttattt
    15241 aactacatgt gcttatttaa tcaactataa atgaattatt tttaataatt gacaaactaa
    15301 attaatgata atatacttta tgtattacaa atgtaagtag aaggaggtat agtatgaaaa
    15361 agttaccaca tatttcagaa gcagaatatc aagttatgaa aattatttgg aaatatgctc
    15421 ctatcagcac tactgaagta attgaaaagt tggtagaaac aagtacatgg agtcctaaaa
    15481 caattcaaac aatgttattg agattagtta aaaaaggagc tttaacatat gaaaaaaata
    15541 gcagagtatt cgtttatact ccacttgtta aagaagaaga atacgtagct acagaaagta
    15601 gttctttttt aaatcgtttt tataatggta ctcttaattc tatggtacta aactttttag
    15661 aaaatgataa actatctgaa gatgatattg aggaactgag agaaatctta aataaaagga
    15721 cgactaaggg ggataaataa atatgtatgc cccattcttt atacgatttt tactcagtac
    15781 attaacctta tcaatattaa ttgctgtaat tttacttgcc aaaaaagtat ttaaaaaaca
    15841 tatttctgca aagtaccaat acaatattgg atttatattg cttataatgt taataattcc
    15901 atttgtccct cttaaatata ttaatcttgg aaatgtattt aactatttat atacttttaa
    15961 tcaacttgga agcagtacta ataggacttc tatgataaaa aatagtccaa attctataat
    16021 taataactca aatgcattaa acgatttttc agtatcccta aaccaagtta attttgatag
    16081 tttaaatatt ttattactaa tatcatggat aattggaatt ttaatcatga tagctattac
    16141 tattcattgc aacattaaaa taaaaaatat gaaaaaatca atacaaattt taagagatga
    16201 ggagatagta tttatatttg aaaagtgtaa aaaagatatt ggtataaata aggattttat
    16261 actatgcaaa tcacctatta taaatacacc tattacattt ggatacttta aaccacacat
    16321 tatattacca gataagtcta tatctaaatt atctttaaaa gatataaaat atatcttact
    16381 tcatgaatta caacacttta aaaataaaga tatactgata aattatataa tgtgcttcct
    16441 tcaaatatta tattggttta atcctcttgt atggtatgca tttaaagaaa tgcgtataga
    16501 ccgtgaaatt gcatgtgata tttcagtttt aaaaaagctt gataaagata gtcatataga
    16561 atatggacaa actctaataa actttgtgga taatatttca agaccatcaa atcttacact
    16621 tacatcagat attggtgggt caaaaaaaca aataaaaaag cgactattga agataatgga
    16681 ttttcataat gaatcaaata cgttaaaatt caaaagcatt ttaattttta cattgatagc
    16741 tttaattgta tttggaaata ttcccaaact atctattatg gcagatatca atgaaaaata
    16801 tagacctaca aatgaacaaa ctgtgtacga ggacttaagt cagtatttta aaggttttga
    16861 tggaagtttt gttatgtatg atttaaaatc caagcaatat catatttaca ataaagaaaa
    16921 aagtaaaaca agaatttctc caaattctac ttataagatt tatagtgcct tattgggatt
    16981 ggaaaatggg ataataacaa gaaataattc acatatccct tgggatggaa agcatcattc
    17041 taatagttct tggaatgaag accaagactt attttctgct atggaaaact ccgtaaactg
    17101 gtactttcag actctagata aaaaaacagg gctaaaaaac atacaaactt atcttaggca
    17161 aattggatat ggcaattatg atgtttcagg tggtatctca aacttttggc tagaatcttc
    17221 attaaaaata tcacctattg aacaggtaga attacttgaa agtttttata caaataagtt
    17281 taaatttgaa gataaaaata tagaaacagt aaaagattca ttgttaatat caaaaaagga
    17341 tggggtatca ctttttggta aaacaggcac tgccaatata aatggaaaag atgtaaatgg
    17401 ttggtttata ggttatgtgg aaaaaaatga aaatacttat ttctttgcta caaatattca
    17461 aagcaaagat tattctaatg gtagttcagc atctaagata acattatcca tattaaatga
    17521 caaaaaaatc tataatcctt aatatattta ctgtacattc taaaaaattc acataatttt
    17581 catattaatt atcaattaaa ttcatataca aggcttatta tataaacata gaagatagta
    17641 aaactagctt aaaaacataa tataataccc tatacaaata gtggcaactc tccctcacat
    17701 cctcaattgt tgccactatt taattttttg tatgaagtta aatatatttt catcatttca
    17761 acaatttggg tgcaatacaa tctctatttt gaaacaacct ctttaattgt tttagagttt
    17821 atgaattatt tctcatactt taaaaagatt gaattactct tgataatctt cttttgtagt
    17881 cattacatat cacctactac tcaacacata ttctttgacc tatttttaca tccttgttta
    17941 tatccaaaat atttaccttc ttaccatctg gaaacaatac cattgttaaa gtagactttc
    18001 ctaattcatg tattctcttt aaatcaacat taacaagaac atctccctgt ttaaccatat
    18061 ctccttgttt aacagcaata tcaaagccat ctccatttaa tgcaactgta tcaattccaa
    18121 catgaattaa tacttctcca ttagttcctt taatcccaaa tgcatgtcca cttgaaacca
    18181 ctgtttctaa tttacctgaa ataggagaaa caatttttcc atctataata tcaatagcaa
    18241 aaccatcacc taacattttt ttagaaaatg tttcatctgg tacattttct aatgcaacaa
    18301 ttttcccctt agctggagac acaaagtttt cattattttc attaaacact aattcttcgt
    18361 cttcatcttc atttatagct tctttaggca ctccaaataa acatgttaca ataaagcaga
    18421 atgcaaccac aaatattgat gctaataagt atgtgattaa attatatcca tcatagatat
    18481 acattaaata agaaggtaaa actgctaatc catatgaatt agattgaata tgtaaaattg
    18541 ataatattgc tgctcctaaa cctgaagatg cacacataat aatcaaaggc tttaaattat
    18601 atcgaagctg aatcccaaat aaaacaggct cacttatacc aaaaagttga gatagcattg
    18661 ctccaactgc agtttgttta acttgattat ttttagattt tttcataaat gctagacatg
    18721 ttccaatatt cgcaaatcca tacattgcac aaagagtaat aagggcatta aatcctgtat
    18781 ttgctaatag tgatgtttca atcattacat aagtatgatg taagccagta ataacagcta
    18841 atggatatgt aaatccaata ataaatcctc caattcctaa aggcaaatca atcaataagc
    18901 tgatgatatc aaccattttt aattctattg tatgcattat agggcctaca cctaacaaaa
    18961 taactaacat tgttattagc ataacaaaaa atggtgtgaa aataaggtct aatacattag
    19021 gcatatgttt acggaaccat ttttcaagat tagctccaat aaatgctgta acaatagctg
    19081 ttaaaacact tccttgacaa cctacaatag gaataaatcc aaatgccata attgcttcaa
    19141 tttcatttga tgggtcagca acagaatatg cattaggaag tattggggaa actaacataa
    19201 gtccaataac aagtccaata acaggtgttc ctccaaatac tttaaatgct gaccatacaa
    19261 taattgctgg taaaaaagca aatgctgttt ctgtaagaac cgaaacaagt gtctgaatat
    19321 acaatggaat atttgcagaa gacattccaa ataatccaag tacattatca ttaaacaaac
    19381 aaccctttaa tcccaagaat aatcctgttg ctgcaataac tggaataata ggaacaaata
    19441 tatctgctag agttctcata actttcttaa atccagtttc attattttta actaattcat
    19501 cttgttcttt ttttgataaa gtttttaatc ccattttttc aacttctgca taaactttat
    19561 taactattcc tgttcctaaa ataatttgat actgtccaga agtaaagaaa acccctttaa
    19621 cctcatcaac tttttcaact ttcttatcat taataatttc tctatcttta accatcactc
    19681 ttaatcttgt ggcacaatgt gtaatagaaa taatattatc ttcaccaata attttaataa
    19741 gctcatttgc tattttatta tatttattca tttttctacc tcactttcaa taatactgca
    19801 tgaaatggtt tcaaacgcac tgttttattt aatagattta tatcatctaa attttggaat
    19861 acaatatcat atttttcttc tactcttatt tctacaggtt tatcagaaaa attataataa
    19921 caatcaataa ctaccaaatc taattgcctt ctatacgcaa taatatcatc actttctata
    19981 tcaataggtt ctattgaacc ataaatcaaa caatcagaat actcactatc ttgtctcaac
    20041 tttatcatct ttttataaaa ttctaaaata ctctctgaat tgttaatctg actctgtgca
    20101 ttaatatctt tataattttc aataaccttt aaccatggtg ttgtatctga aaaacctgca
    20161 ttttctttat ctgcccatgg aaatggcgtt cttgcattat ctcggcttct taaattcaca
    20221 aattctaacg cttcttcttc tgagtaacct tcatctattg aacgatagta ttggtcaatg
    20281 ctagataaat cattaaaatc atttatggta tctcttttaa aatttgtcat tcctaattcc
    20341 tgtccctgat aaataaatgg ggttcctctt aaaaagaaat acattgctcc caacattttt
    20401 actgcatcat cattcctttc gtattgcaaa agatactttg ttgtagctct tggttggtca
    20461 tgattttcaa taaaattagc tgcccatcca tgttcctgaa catacatttg actatctaaa
    20521 atgcattttc ttaaatctgg aattgtccat gaaattcttt taaaccactc actaccagaa
    20581 gcaacatcta agtcagcatg tttaaagtca aagaccattg aaaagaaacc atcttctcca
    20641 ataaaatcac ctaactggtc atagctaata cctgctgctt cagcaacagt catacaatca
    20701 tattttttaa acgtattttc ttttaattca taaagcattt tttctattcc aggctgattt
    20761 ctaactgttt ttgtacattt aacaagacca tcaacaccat cactttctaa actttgaaaa
    20821 cttaaattct ttttgatgaa tgtaatagca tcaactctaa atcctgccac tcccatttga
    20881 gaccaggtat taatcatttg gtaaagttca cttcttaata ttggattttc ccaattaagg
    20941 tcaggttgtt tttttccaaa agaatgaaaa taatattcgt ctctattctc taccttttcc
    21001 caaacacttc caccaaaaac agacctccag ttatttggca aatcgtttcc ttttttaaaa
    21061 atataataat catgataagg actttctgga ttttttaatg cttcttgaaa ccaaggatgt
    21121 tcatcacttg tatgattaag aactaaatct aatataattt tgattcctct atctttactt
    21181 tttttaatta actcttttaa atcttccata cttccaaatt cacttgcaat atccaaataa
    21241 tcactaatat catacccatt atcatccata ggtgatttaa aaattggaca taaccacaat
    21301 gatgtaatac ctaaatcttt taaataatct aaacgagaaa taattccctg taaatctcca
    21361 attccatcat tattactatc ttgaaagctt cttggataaa tttgataaac gatttctttt
    21421 tgccaccatt tcttttccat aaattactcc tttttatatg atatttcttc tttttaattc
    21481 tttataaatt ccattatcga atatgtcctc acatatagat gtcgctatat ctttaagttg
    21541 ttgatgacta tttttcattg caattgtaac gtctgatgct tgaaacatga caatgtcatt
    21601 ttgaccatca ccaaaacata tggtttcttt ttgagttact cctaatcttt cttgtaatct
    21661 cttaattgct ttgcccttat gaaaatcttt ttgaataatt tcataatact gactagaaat
    21721 atctctctgt gctaattcca ttttatcttg tagtatatct ttcacttcgt caaatacctt
    21781 ttcatttgac cataaacaaa ttttatgtat atcttgtgac ttatactctt caatgttatt
    21841 ttcatatgtt attttttctt ggatatgttg tttatttata caagaattag ttcctttcaa
    21901 ctgattcatt gtttcaaata tttctttggc tttttgattc atgaaaactt tttcctgact
    21961 ctcaatcgaa aaagcaactt ctctattttt taataaacaa acaacttcct ttatcaatct
    22021 ttgattaaaa gattgattat aaagtaattc accatgatat tgaatgtaat tacctcctcc
    22081 tgcaatatat ccatcaactc ctaatgataa aacatcatct tgtattgtac ccatacttct
    22141 tccagtacaa ataacaacac tgcaatgatt cttttgacat aaacgtatag catgctttgc
    22201 agattctggg attccatata cctcatctct aagcgtacca tctatatcaa gtattaataa
    22261 tttgtacaat ttcatcttcc tttcttacta tcaaaatcat aatagcattc aaaaaaaaag
    22321 atatcaatat tttgatatct tttaaaaaat atgttcattt ttagcacaaa ttttcatttt
    22381 cggggaatat gttcactttc taaatacatc ttgtatttaa tataaagcag ttcaattaaa
    22441 ataaaataag gtgttgttac atcgtagtcc agttgtttat ctacagaaat agatatagat
    22501 tgaatataca ggttttcatc acataatctt gctaaaggat tacttatcat ttttgtaata
    22561 gaaaccatat aaattccttt cattctcatt tctttagcaa aatcaataat tgtagatgca
    22621 tctccattca atgaaataaa gaaaatcata tcatctgttt ttataaaatg attaagtgcc
    22681 tgaatcatat cataaccata aacatcatat ataattttcc ctgttggtaa gaaaatcctt
    22741 ttcatctctt tagcaactct ttcctgagaa taaccttctc caaagacgat tatacgattt
    22801 gcctttttca ttctttcaaa cataatcgaa caatccttct tctctatatc atttatcacc
    22861 ttattatagc aatccattaa ttggtgttta ctttgatttt tatattctac ttctgtttca
    22921 tttaagcgta taataactct taattcacta tatccaggta attgtagttt ttgagcaaaa
    22981 cgagaaagtg cacttgtaga tatatggtat ttgtctgcaa attcatctat agaaagttta
    23041 atacaatctt ctttatgatt aagaatacac tcacagatat acttatcatt tgctgtaaat
    23101 gaattataat atttattgaa aagtccttca attttcattc ttttctcctt ctatactcta
    23161 tgtaattcat atgaagcaaa tctaatagag cataaaatgc tcctacgact tcataagata
    23221 tagcttgtaa tgtatcaagt ttttgagttt caacatacag attatactca caaagtgttg
    23281 caattgtatt attatcaagc ctagttaaag aaatcgtatg tatatgattg ttgataaatt
    23341 ttgcaatttc aattcctgct tttgtttctc cagacaaaga aatgataata aataaatcac
    23401 ttttttgaaa tgattctctc ataaattcaa tttcacctat atcaaataag tcaataacac
    23461 atttacctac tgaaagaaat attctcttta tttcttgagc taaacttttc tgttcattac
    23521 ctgtcccata aatataaatt gtttctgcat catatattat tttacaaata tcttgaaatg
    23581 atattttttg taattcattc attaatagtc gataattctc gcaaacatca tgaaaattat
    23641 tatcattatt aacaaattct agttgattat ttttaagtaa atactttaaa tcagagaatg
    23701 aatctaatcc aatttttcta caaagcctta ataaagtagc tctagaaaca ttacattcat
    23761 ttgcaatttt ttcacacgaa aaattacggt attctctttg acaaatcaat atttgtttaa
    23821 taataatttt atcattttca tttaaattat cataattttg gttaactaac gattctaatc
    23881 tcattttttc cactccctaa atattatttt aatatacatt agttgctttt tctagggaag
    23941 agttttaaat aataaggata aaataatcat ttgattttat ttttattaaa ataaaaataa
    24001 cctgctaaaa gcaggcacca aaaagtactt atcctttcga acatgtactt tagatattgc
    24061 tttcttcgga agcttcatct cttcatactc taaaatagag ttttttctaa ctcaaaagta
    24121 ttttccatgg tagaaattac tttaattcat ctgccattta ttttttatct tatttaataa
    24181 ttactactac ttgaatattt acttctttaa gtaaatttca tagttaacaa agctaaaatt
    24241 attattatag atgttaaaat acaaaattgt aagtattgtt ataaatatgc ttacagctac
    24301 aaatatacat gatatattaa aaagaagctg taaattatta tcatacatac aagcaactac
    24361 gcctctatta atccatgtta atttttatta tttaatacaa ggagttccat gagacataca
    24421 tatccattca tattttaaat tatccaattc tcttatagat ttcatcatct ttttataatc
    24481 ccaattccat ggattaggat aaggaactat atttccattc ttatttttga ctaaatcacc
    24541 tgcaaataat acatcttcaa aaatcatgca gacatgccct ggagtatgac caggagtatg
    24601 gataattttt atattcccaa tctgcatatt ctctccataa ggttcaacat ccttaatgag
    24661 ccttctggaa attgcctttc caataaactt cttaaaccca ggtctatcct tctctcctat
    24721 aataaaaggt atatcctcta catgagccca tacttttgct cctgtttttt ctttcaataa
    24781 tttaatatta gatatatggt caacatcatg atgagttaat aaaatatgct taatatctgt
    24841 aagtttaatg ccaagtgttt ttaattcttt aattatattt ttccccataa aaggaagacc
    24901 tgtgtctata agaataattt ctttatcaaa cacaataaaa caatttgagc cacgagtact
    24961 atctaacatt aatacatttt cttttatctt cataaataaa ttccccttat ttggtatttt
    25021 acctatataa ttaattaata aagttataaa tagttataat acttgatatt aattttattt
    25081 tttattaaag tatactatag gtatacaaat attatattta cataaatata ccatcagtat
    25141 acttttttat caatagaaag gaataattta tatgtcagaa ttatcaaaaa gagataaaga
    25201 aaaaatacaa agagaaaatg agattattga taaggcagaa aaattatttt gtcttaatgg
    25261 atttgataat acaactatga atgaattagc aaaagaagtt gaatatacta aacgcaccat
    25321 atacaagtac ttttcatgta aagaagattt attctttgct gttgtcttaa gaggatataa
    25381 aagactttgg gataatgtta aaatagaaag tgcaaaaggc aaaacagggt ttgaaaaaat
    25441 aaaactttca tactttgctt ttcataaatt ttactctgta gaaccttctc tattatgcct
    25501 tatgggaatg attggtattg taaactctga aaaatcggat actgatatgc tgtttaaaga
    25561 aaagtttttt tcttttaata aatttatgtt tgatgaaata caaggaatgt ttgaaattgg
    25621 aaaaaatgat agaagtatta ggcatgatat tgaaatacct actcttatgt attcatcaat
    25681 atttacactt acaggatttt ttaatttact atctgtaaca ggaaaatcat acctgaacaa
    25741 ctttaatata gatgaggaaa aatttattga aacaactctt gctcttttaa tagattcaat
    25801 taaagcataa acctaagttt ataaattaaa gtttatatac ttaaatgata attttttcta
    25861 tctctaatat gaaaaatatt aaacataaaa ctaataactt agttaatgga ataactaaat
    25921 tactgaaagg attaaaagta aatggctaaa atacttcttt tagaagataa tgatacaatt
    25981 acatttggaa taaaaacttc ccttgaaaag aaaaatcaca ctgtatgttg ttataatacg
    26041 attgctgaag ctaaaaaaaa ttttgataaa actattgatt taattctgct tgatttaaat
    26101 ctacctgatg gtattggata cgagttttgc caatatgtta aaagtataga agatactcca
    26161 gtgatatttt tgacagtccg tgatgatgaa aaagacatta tacgtggatt agatatgggt
    26221 gcagatgact atgtggttaa accgtttttg ctctcagtac ttcaatccag aattaatgca
    26281 gttcttagaa gaactcattc aaatactaac aatactatta catgtgaaaa tataagcttg
    26341 aataaggttg aagtcaaagc atatttagat aatgttgaag tacctttgac agcaggagaa
    26401 tataaacttc ttctaagtct tatggaaaat aaaaatagag ctatgactcg tacaaagtta
    26461 ctagaaatgc tctgggatgt agatggtaat ttcgtaaatg ataacactct tactgttaca
    26521 ataaaacgtc ttagagaaaa attaaaaaat ccaccttgta taaaaacatt aagaggcata
    26581 ggatatagaa tggaggacaa ctagtgaaaa ctccaagaaa tatcaacagt acagttgttt
    26641 ttataatatt ctgcttaatt gtaacttttt tattgagtgt aattctaaca actataactt
    26701 cttttaatga atacaatgta ctgtctaagg ctcttggtgc atcatatgag tacaatccta
    26761 agtctacaga aagtatacta aaatcactga aaaattctag tgataaggat tttaaaacag
    26821 gaaatgaaat tttatcaaaa catggatatt ctaaaagtac attttggagt aaaaactttt
    26881 tttattttct agtgatatcg tttggtataa tttcaacaat ggctacagtt gtatatataa
    26941 tcaaacatag aacaaataag caaaaactga gtagaataaa caatcttact caatacttag
    27001 aagaagtgaa tttaggaaaa gagtctgtac ttttacgatg tgaagatgaa ttttctcacc
    27061 ttgaagatga gatatataaa acagttgggg aacttcgttg ttcaaaagaa tttgctttaa
    27121 aagaaagaca aactctttca gataaccttg cagatattgc tcatcaactt aagactccaa
    27181 ttacctctat gtcacttatg gcacaattac tttcagaaaa ttgtccagat gaagaaatag
    27241 attatattaa cagacttaca aatcaaatct caagacttga gagactagtt tcatctttac
    27301 ttacattatc aaaattggat gcaagtactt taatatttga aagcaaactt atagatgtac
    27361 attctcttct tacttatgca attgagccta tagaaggttc tttaagagaa aaacatcaga
    27421 catttactat cgaggcttct ccttcggtag aatttgaaat cgatattaat tggactttag
    27481 aagctctttt aaatattctt aaaaattgta gtgagcatat agaagatggt ggatatatag
    27541 ttgcttatta tagtcaaaat cctctatatg ttgagattat catagaagat aatggtaagg
    27601 ggtttgctca ggaagaactt ccatatattt ttaatagatt ttatcgtggt aaaaatgcta
    27661 gtaaggacag tattggtata gggcttgctc tatcaaagtc tattatagaa cgtcaaaatg
    27721 gtactctaca tgcagaaaat tgccataatg gtggtgcaag attcataatt aaattttaca
    27781 cataaaatgc tggattatag gtaaaatacc tataatccag ctatatctat attctatgtt
    27841 atctattgtt ttagtaatat acttctattt acatttaagg ttttattaaa caaacaactt
    27901 aactatccct atacttgtaa gtagtcttaa atcgaaacct ttaaataagt tcaaatagat
    27961 tttgtttata ttgtttcatt ttttatagat tctactatat tttcattctt caactgcttg
    28021 tatcctgtca tatatgatgc tattacaata aaaagtatca atatagtaaa acctattatt
    28081 gtagatatag gtgcaaatgg taaatactct ataaaatata tttcatttat acgtagaaaa
    28141 gcatacacta ttcctatttg cacaggaata ctaagtagta atggtgtaat tcctaagaat
    28201 aaaccttcca aaataagcat cttttttatg ccttctggag ataatccaac agaacgcaac
    28261 atagcaaact cttgtcgtct acttctaata tttcctgaca ctgtagcaag tacatttgat
    28321 aatccaatca tagccaataa acctgtaata aagcctacta ttaaattcat ggtctttatt
    28381 ccactagcct tttgtttttc actttctaaa acatcctcaa tactataatc tcctgaacca
    28441 tagtctttat tataaatgga ctctaatttt tctcttactc taggaatgtc ctcacgatta
    28501 tttactttaa atactcctat cagcctattt gaacgtaacc tacttacttc atcataattt
    28561 ttagatattt cctgcaccat agacattgga actatttgca ttaatgtata ctttgaacta
    28621 gtatctacta ttttaggaag tgtgcttgta atagctccca ctttcatgtt gtaagtataa
    28681 tcccctttat cttcgtcata tactttttca tttaatttaa tgttatctcc tattgaaaga
    28741 tttaaataat ctatatatac tttatttcta cgtgtactac gattaatatc ttcctcctta
    28801 ttatatacaa ttgaggttgg attttttgta tcataaaata actttgggtc tacagaaatt
    28861 tgcctacaat attctgtaaa actcttatca tcaagcccaa ttatatttga aattatacga
    28921 aacttgccat cacgttctat aggagagtac tttttagatg aagctatatt tttaaatcct
    28981 ccatttttcg caagttcttt tgaagcatct ttttcagtca accaagtgga agcagacatt
    29041 ttttgataat atagtgaact ttttacacct tctgtattat ctaatttttc aatgaaagca
    29101 gactctacag gttcactatt ttccaaataa actgctatat ctctttggtc cttataatta
    29161 tcacttccat aaacagcttt tgctccttct tgatttgcaa ttatatgcaa aaaacatgta
    29221 agtaataaaa aagataatgt taaagatatt gttgcagtac gataagattt tttacgagca
    29281 cgtagtgcgt ttgatgcaag ttctccttct attccaaata tctttcctaa tgaatattta
    29341 tgcgactttt tgattttaac actatctcct tgtcgtattg cttctatagg agatatcttt
    29401 gatacttttc gtgctggtat aagtgcagaa atccagactg ttactattgt aagtaaaact
    29461 gctggcagaa aagcaggaat accataagta aataccactt ctggaacatc agtatgataa
    29521 ttaactgaat taacataaac tataagccta ttacacaata accatcctaa aaataaacct
    29581 attggtaatg gtataattgt cagtaaaaag ccttcaaaca ctacagacct tttaatttgt
    29641 tttggtgatg caccaacact agataatatc cctaattgag taagtctagc atttgcagac
    29701 agtgaaaacg cgttgtaaat caccattaca aacacggcta ctgtaaaaat tgctattgta
    29761 agatacataa taggagttga aaattttgat atactactca tagatgcttt ctgttctggt
    29821 gaaaagacta acatctttaa aagataatta ctattgtatt taagattgta ttttccatat
    29881 tcattagtct tccatcccaa tgatttagca agttttggaa gttccttata cgtgtctctt
    29941 atatttttaa atcgcaagta cacagttata ctatcattag gttttatact tgttttatca
    30001 agatatccaa gagctgtata tgcaggtatt actgatgaag tagaaacatc tacctttcct
    30061 actattgtca atgtagcctc tgaaattttt ttaaaacttt cccctttcga ttttggggct
    30121 atgggttcaa gaggctttcc atttaggatt ctatctccta ttgggagagt aattttatca
    30181 ccaattttta cacttggatt attctcaaaa tattgttttg ataatgcaat ttcattagca
    30241 ttatttggtc gacgaccctc tattatagta tccttttctg gcatagaatt ccaatactct
    30301 gatgtagcat ttctataaat tatataatct cttttctcat cattaatttt gcctacatac
    30361 cattgtcctt ttaccattac atcatcaact gaagaaaaat tttcaattaa tggtaagtca
    30421 cttccataag tatagtcaaa caattcacca tgccagttac cttctttctc aattgaaagt
    30481 tttataaaat ctgtccacat ggtatacaac agtccacaca aagaagacat catggttgta
    30541 gtaagtaata tagctaacat tatagctata ctactacgtt tattgcgtcg tacaaagtct
    30601 aaggtgtatt cttgaagaat attcatttct tcaccacctt ttcagagaca atcactccat
    30661 cttccatagt tacaatacga tttgcctcta gtgctatttt ctcatcatga gtaataagaa
    30721 gtattgtctg attaaatcgt ttatttgata agtttaacaa gtctacaatt tcttctgaat
    30781 tttttctatc aagattacca gttggctcat ctgctaataa aatagctggt ctatagatta
    30841 aacttctagc tatagatacc ctttgttgtt gtccacctga aagttgactt ggaagatggt
    30901 ttaatctatc agataatccc aatatagata caatctcaga gaatctatcc tcatccacct
    30961 ttcttttatc aagtaacatg ggtaataata tattttttct aacatcaagg gtaggtataa
    31021 gattataaaa ttgataaata agacctactt ttctacgtct aaaaactgca agagcttctt
    31081 cctttaaact tgatatttct gtatcttcaa cataaatctt tccagatgta ggtctatcta
    31141 ctcccccaag cagatgtaac aatgtagatt tgccagaacc agatgctcct acaatggata
    31201 caaaatcacc tttttgaact gataaattta cattattaag ggctgtcact ctggtttgat
    31261 ttgaaccata tatttttgtg agattttcac attttaatat ttccatatac aatcatctcc
    31321 tttatggtta aattttagca acctaaaatg acattatagt gacatgaata caaatataaa
    31381 ttactattaa aaatattgtt tagtttttgc acattattta aaattataat ataaaacaaa
    31441 aactatgcaa tatattttat ttatactttt aatatattac atagtcttta aaaggtatta
    31501 actttaaatc tataggtatt caatttaata atcaatagca agtattttat gtactaaagg
    31561 agttttgctc tatatagact caatttagta aaattattta ataaatatta cagactatag
    31621 gtaaataata tttacaaata aaattaagtt tattccctta cactataata tttcttaatt
    31681 atattaattg caatttcctt tacctttggc cctgtaattt ctttattgga atcatctgat
    31741 ttaatagcaa aataataggt gtcaccttca cgctctagca taccaacaaa ccatgcatcc
    31801 acacgtttat ttttttcatc aaatcctgtt ccagtttttc catatacatt tatgttttta
    31861 tcatttacat ctattttcat aatatctctt aaaatattaa tatgctcttt tttaaagttt
    31921 gtatctccct caaatatttt tgccattgtt tgcacttgtt cttttggaga tatttgtaat
    31981 gaagattcta accaaaatcc atttaaatgt ccctttccat tttttaaatc tccttcccat
    32041 tcgctaatat cgcaattccc atactttaaa tcatctaaaa tgttttggac agatttagca
    32101 tcaactttat ctatcaattt tttgtagtac caaacacaag actccttaaa tgcctcttct
    32161 aaactaagat ttttattcca atttttattt ggatactctg taccatcata tcccataact
    32221 gattcttttg agtttattac ccctttttct aaaccaatta aagttgaaac tattttaaaa
    32281 gtagaacatg gtgaccttct tgtttcaatt aattctttgt tatatatatt atattcttta
    32341 tttttagtat tataaaaaat agctcctcca ctaatacctt caaaacaatc actatagtca
    32401 accatattaa ttttttcttt tttgttttta ttattgtttt caattttgga tttatttaat
    32461 tcagacttat ttaattcaga ttttatataa ttcttatcag ttttttgatt tatatcgtta
    32521 tgttttttcc ctacataata cattaccata actacaccaa ccaataagat agctatccaa
    32581 ataaaattct tttttctttt cataatttat atcatctccc atatttaaat ttataaccta
    32641 ctattaaaat agtagacatt atttgtaata tactccaatc taggttctac ttataagaaa
    32701 caagactaaa tgaatagctg tatctcttat attttcttca cctagtacaa ttatgttgat
    32761 taaacctatt gcgaagataa ttaagtaact attaataaca tcctgtcctc cttttaattt
    32821 gtgatataat aattgattcc acatttaaaa cttactattg taatatttaa atattacaat
    32881 agtaagtttt aaatgtcaag ttagtttggg aaagttattt taattgtata attgttatta
    32941 catttataaa atatggcatg tttaaaatta ttttgctatt gggaggatta agataagcag
    33001 tattataaaa gctataaatt ataaaattta atatataatt tatagctttt acttttacaa
    33061 atattgtttt tattgattta ttaatgaatt ttattgacag gttatattta tataagtaaa
    33121 cacttacata ataagtatat aatctacata tctataagtt gagtcaattc accagtatat
    33181 gtcaacttaa gtttatgcat agctcgtgta caagcaatat ataacaaact gcggtcataa
    33241 tcactataat atgttttatt atttactgaa ggtacaataa cttcatcaaa ctctaaacct
    33301 tttgacattt taatagaagt tatggatact ccttttgtaa agctagaact ttcagaagat
    33361 attaagtgaa cactatattt ttctcttaac gcatcatata cagctttagc gtcattatct
    33421 gtctttaata taataccaag agtcgcatta tcactctttt taaattcttc aatttctatt
    33481 tttatcttat ttatttcatc ttgctcgtta ttacatttta ataaagctgg ttcttcacca
    33541 tgtcgttcaa taggctctaa tgaagatatg tcttgaatct ttttggcgaa attaataatc
    33601 tcaaaagtag aacggtaact cttattcaac ataactagtt ccccatcatt atatagctgt
    33661 ttcatatcat ctagtgtatg agtgtgatta ggattaacca attgtccaaa atctccaaga
    33721 atagtctttt tacacttaaa aagtaagttt attacagcat attgaatagg tgtgtaatcc
    33781 tgcatttcat caataacaac atgtcttata atcttatctt cttgtatacc ttcatatgca
    33841 gcatgaatat atataaatgg gtatacatct gaccattcaa gagttttttt tgttgccatc
    33901 acaaacatgt ttgatatatt catttgttta aagaaatcct tatatagtgt aagagtattt
    33961 tttattgtca acattccatt caaactttta agtatacttt ttacctttgg taaatcttct
    34021 tccataatat tatctgattc aaatttataa tgaatgtctt cagctacctt ctctaatctc
    34081 ttcttaactg gatatctgtt atatgcctca aatctactct gtatccagtc acttttagct
    34141 gtaaaacttc caaaagtgta gtcttttgga ataaaaatct tatttggcat ttgttttata
    34201 taatcatcaa taagttttac aaaatcaagt gtagatttaa aacgcactct ttcagaccat
    34261 ttagcatcat ttatttctaa tgggtctttc tcactttcaa aattaataac tctatctaat
    34321 tgtacctctg ctatattttc aaaacttaat tcacataatg gctcttctcc aagctcagga
    34381 aggacattgg aaatatagtc tccaaagact ttattaggtg ataggataat tacattattt
    34441 gctgatattt tatctttaaa tcgataaaga agaaaagcaa ttctgtgtaa tgctatagat
    34501 gttttcccag aaccagctac cccttgaata atcagtgtat cagctttatc atttctaata
    34561 atttgatttt gttccttttg tattgttgaa atgattgact tcattttttc atctgaagtg
    34621 tgactaagtt ctttttgaag aatatcatct tgtatattaa tggaactttc tagtgcatat
    34681 tctaattttc catttttaat tttaaattgt cgttttcttg ttatttctcc atccacccat
    34741 cctattggag catcatatcc agcttttccg atttcataat cataaaacat actggcaatt
    34801 ggagaacgcc agtcaagtat tataagctca tcttcataat caaatgcaaa tctaccaata
    34861 taatacttag attcatcatc catatctttc agcctaaaat ctattctagc aaagtatgga
    34921 gaatctttga ttttattaat cttatctcga acttttacca taaaagcccc atagttatct
    34981 atttgtttta gtccttgttc attttgaaac atttcatgtg ggtctatttc accacgattt
    35041 tttaccatat acattttagc gtccatataa tccttatcaa gcttgtcaac aagattttca
    35101 gctttcttaa aagcattgtc tagcttgtta tttatctcta ttagatgtgc aatctcatct
    35161 ggaaaaaaag ttaataactc tgcatcatat tcacacatat tatgtttaga attagatgca
    35221 ataatatcgc aatttactac ttgtttattt tcagacattt aaatcctcct ttgttaatta
    35281 agtacttaca ctgaatcatt atacttaatt gtgttttgga gtttttaatc attcttgcta
    35341 tttaacttaa atgttagctt tttagcttta aagttccttt tttaaaaaac taaatctttc
    35401 tatatttatt accataagta cacttacaag caaaatacat taaaagcaga aatgctctta
    35461 tatataaaat aattcaaaca aaaaatatgt ggtaaacttt tcatttaatc tacaattaat
    35521 tttgtctatt atctctttct tctacacaag gaagaataaa tttttgagta ggatatccaa
    35581 attccacaag caattctgct tctgcaaagc ccaacttctt tatcatatct ctatgtcctg
    35641 tatcagcttt gtcaccctct cgaaaggtag taattgaaat atctgtatct atcaagaaat
    35701 cttcaataac tttcttcaaa aacacttgtg caatgtctga attacgatac tgtggatgta
    35761 ttccaaaaaa atcaatactt ctagtttctc tattaaacac catatttgca atagcgacat
    35821 tattaagttt taatattaaa gctctttctt ctaaaatata ctgttctaat tgatatatat
    35881 attcttcctc ttgcaaattt ggaaatccat ctatgactaa tctcactaaa ttcatccata
    35941 atggtatgtc agacatactt gcaagtttaa tttctttttc caactctagt acattctttg
    36001 aaaataggtt atcttttttc aaaacaaatc ttagctgcaa aggataaaat tcttgttctt
    36061 tcctatattt atttggagat tttttataca tagctttaaa tatagaagtg aatgcctgtt
    36121 gactttcata tccagctatc aatgcaattt caataattgg tttctttgaa aataccaata
    36181 attttgctgc ttctgtcaac tttctccgct ttatgtaatc atgcattgtt agaccaacag
    36241 aagttgtgaa agttctatgc aggtgatatt ttgagtaatg aacagcatta gcaactatat
    36301 ctaaatccag cttttctgat aaatgctcct ctatatagtc aatagcagtt atgacattaa
    36361 ttactttgta agacattgca gcttccctcc ttttatccat gcaacattat atcaattatt
    36421 acttagttat atttaatgaa tcttgctatt ttataaacaa atttgttgtt taagttttca
    36481 attcataaat ttaatatatt actttttact ttctgattaa agactctaat cctttaattt
    36541 tcaataactt ttcatttagt aaatctaaaa agttatttat tattttcttc ttattagatt
    36601 ccttttatat tccttaatta aatgataaat atttatatta tacgactaaa aacagctttt
    36661 tacaattatt taatatgatt acaaacttac cctatcttaa agtttaatgg ggtcctgtta
    36721 tgaatctttt tattttaatt taagctcttc atcagtttat tttatatatt gatgtatttg
    36781 atttcataca aaaaagagtg cttcatgaac taaaaagttc atttttaaac actctctttt
    36841 atgtaaataa atttctattc tattttgaaa tattataatt tgacttataa tctgttaata
    36901 ccaaaaataa taaattgtac gtctaagaat agattctaat tagttgctca gtagtaaaat
    36961 ctgtttttaa ctaatcctgc tttgtatgtt gaacatattc tataattgta ccatctggat
    37021 gtctcaatgt catattatat cctgtaggaa cttttttctt atctcttact acaactgctc
    37081 cattatccaa tagataactt ctccattcat caacagaatc aaccataaaa gtagattttg
    37141 tttctataaa tggtttaaga gcatcatcag aaccagataa tagtaaaaca tttcctattt
    37201 gcgctaattc caacccaact tctttatagg aaaaacgcaa agaacatttt tcttttaaaa
    37261 gattttcata aaaaggtatg gctttttcta tatcttgaat ataaaaacgt gttaatatat
    37321 catatatttt catattttcc ccctatatat ctatataata ttacctctaa attataccac
    37381 tctacaaatt atataacaat aaattaagca tagccttttg agcatcttaa gtagacctta
    37441 acaatatatt ggggttacat tagaatacat aaattaaatc accttgatat tatttaggat
    37501 aaaatttatg tagtagcagt aaatgttctt ctaattatca actaacaaac gataatcttt
    37561 aactttctat ataatgggta acatcatttt cgtaagatat tcactagctg gacgattgat
    37621 atcatttaaa tactggtaat atatatcgcc atgaagttta tatccattgc tatttgccca
    37681 tgaaaataag tcttctaaag tagggtcttg taattcataa ggtcctaaat caattgcagt
    37741 tattattttc tgtgcaggaa caatcctttg tagaatctca tttttcccat ctatataagt
    37801 ggctacagga aaccctactt caacatccaa ttttgctaaa tccatgttat gaaaacatac
    37861 aatcggtgct cctgaagata aaattcctct ctcctccaga tatttagaaa ttttttcaaa
    37921 actttgtttt gaaaactctg aaaactctac cataaagtca attgtttttc gtattgccaa
    37981 aaaacagtac tcagattgtt cagctattgt tatattggat attctagtca ttttattcct
    38041 ccattacttt attttcattt ctaatctttt tataccaaat tatacgaaaa tttactgtgt
    38101 aactaattat ttcatatgaa tataaaacat aacctccttc catttcttat atcgaaagta
    38161 tagcaaaaat aatctcatca ttcttgtcac acagtgctct tataatcaga acatacttaa
    38221 aagacttgcc taatttttag gcaagtctaa aagaaatctt tttctataaa aaatttatac
    38281 aaacaattaa aagatcaaaa tatagactaa tataaaacta taaatttact aatctgaacc
    38341 tcccatggct aaagtcacaa gattactgat ttatagaatt tcgcacacta aaatatgtct
    38401 tactaattcc ccacaggcta cccccctagt tcctacgttc ttacataagt tatctattat
    38461 caaacatcaa aatttaaaca agtttcaggt tcatcttcta ttcttgctat tttaaactta
    38521 catgcaatta atactaaaga tactattgga tttataatat ttaataaagc gtatggacca
    38581 tatgttagtg cagatacacc taatgttgct gttatatacg ccccgcatgt attccatggt
    38641 actaatggag aggttaaagt tccactatct tctaaagctc tcgacaacat cttaggatgt
    38701 atacctctct ttttatattc cttattatac attcttcctg gtataactat agatagatat
    38761 tgttcacctg ctattatatt ggtaattgta caagttacca tagtacataa tactgttcca
    38821 aatacaccct ttgctaatct tagtaaagaa gatgctacta cttcaagcat acctgttttt
    38881 tctaaaatac ctccaagaga taaagcgcat attgttaagg atacagtgga catcatattc
    38941 ataatcccac ctttagataa taaagcatct acctcctgta tttgtgttga cgaaacatat
    39001 ccattttgtg ctgcatctaa tatcgtattc atagattctc cttgaaaaac tactgcaaac
    39061 aatactccca atacagcacc tactataagc cctggtatag caggaacttt aaatacaacc
    39121 aatccaatta ctattgctgg agctaataat aatactggtg ataaagtatt aaatgtagaa
    39181 tctaatgtag acctaattaa ttctatttgt tttatatcta gtgcttgacc tgaatacttc
    39241 attccaatta caccataaat tactaaacaa attaataatg atggtatagt cgaatatagc
    39301 atatatttta tatgtgtaaa caaatctgtt cctgccattg ctggagctaa gttagtcgtt
    39361 tcagataaag gtgatagttt atctccaaag taagctccag atattataga acctacgatt
    39421 aatccaattg gcatacctaa actttgacca atgcctaaaa gagctactcc tactgtaccc
    39481 attgtgctcc aagatgaacc tgtcgcaaga gatactattg cacagactaa tgttgatgct
    39541 actaaaaaaa tatttggtga taaaattttt agtccccagt aaatcataca tggaactact
    39601 ccacttacta tccaagttcc tataagtacg cctattataa ttatgattaa gattgcttgc
    39661 attgccatct ttatactatt aaacatactt aattctaact ctttccattt aaatccaagt
    39721 ctatatacag ccacaagtcc tgctactgct gctgctccta ttagtggtac atgaggtgat
    39781 gaaccataca ctaatactcc tagacttaaa aataatatca aacaagtaat tggtatcatt
    39841 gcatcaaaca gacttgcttt tctacattct cgctctttca taaaatagtt tcctcctaat
    39901 tatttaaaca ctacactata attttttttg aaacatattt gctcgtacta gatgacatga
    39961 tacccccata agttaataaa aattctaaat tgtcacctaa tttataatca tattttgtgt
    40021 tacttacatc tagtatcatg tggtctgaac ttgcccctaa tatttttata tcagtgtcta
    40081 ttggaattaa agagtcaata tttatatctt gtttacctat agctatgatt gcccttttta
    40141 agattccctt atcttcataa acaggtttat ttctaaaggc atcaactcct atttctccaa
    40201 taggaactga tggtttttct ttacattcaa ctacttggca tattaattta aatgcatctt
    40261 gatatgttcc atttatattt tcaccgtatg ccgtttctct accaagtaga atggactcgc
    40321 ctattctcaa attagtaata ccttctggca tattattatt tatcaacaga tgaatagaac
    40381 ttgaattacc tccagatact atttctagat ttattccaaa tttttcttcc attctttttg
    40441 ctatacttac cagtctgcct atattttccc tagatggtat aatagctcca taacaggtta
    40501 agtttgtagc tataccaatt atttcaatat tttttaatct tactatctct cttacattac
    40561 taaaaaagtc ttcttcataa aagtatcctt ctcgtaaatc gcctaagtca aacataagaa
    40621 ctatcttatg aataatattt ttactttcac ataattcatt taatttcttt attgttccta
    40681 attctgagtt aaaactaata tcgcaataat tgataacttc ttctaattca cttaacattg
    40741 ggattctaat caatatctta ggtagattta tatcttgtaa attttttaag ttttgtattc
    40801 ttgaatctgc tatatggtct attccttcac tacatatttc ttctactatt tctttttgtg
    40861 cacaaaatga tttagtaaca aaagatatct taatatttct ttcatgacac atctgcgaaa
    40921 ttaattttgc attatgcttt aacttttcta tatctatttc taacctagga tacataatct
    40981 ttcctcctca aaattcaaac tttttaacag gagcttaaga gatgcttctt catatttttt
    41041 agataaaaca cccatagatg ccataatata gtcattatct attaatatct ttgttttttc
    41101 ctttggaaat agtaattcat tatttttatt gtatttgagc atattatcta atatttcaat
    41161 tctactaggg agcctagtaa gtgctccccc tgtaccaact atatatctta cttctgttaa
    41221 atctttccct tctgcaattt tgacttttcc agttgttcca tagatatttc ttatttttcc
    41281 tgaatgtctt agcatagctt taacaacagc ttcttttgtc aacctctcaa caaataatat
    41341 ttcttctttt gattttggta ttggaggata attctctatt actgcatcaa tatctataga
    41401 tagttcactt tgtaagtttt ctttacctat aacttctact atattcttca tatttacata
    41461 tacacctaaa tccccctcaa cacttctctt tgcagtaggt tcaggattaa ccaaaatttt
    41521 attaatatag tcacttccat ctgtaacaga atgtacatca gtagttgctc cacctacatc
    41581 cagagttaat aaatctccaa tatttttata taaaagttta gaagcttcca ttacagctcc
    41641 tggggttgga gtaatatttt cattaaccat ttctttaatg tatttcattc ctggtgctgt
    41701 agttatgtgt tcttcaaata cactttgaat gattcttctt gtaggttcta tattcaataa
    41761 atctatttta gggtatacat tttcagttat ataaagctta taattagtat cttcaaatat
    41821 taaccttatt tcctcttgat tttcaacatt accagcatat ataactggta tgcctagatt
    41881 catagaagct atcatttctg cattataaat agctgtatct ctttctccat aatcgactcc
    41941 accagctatt aaaattatgt ttgggtttat ttcttttatt ttatttaaat cagttctttt
    42001 aattctacct gatgttattt gacgaataac agctccagcc cctaaagctg cttctttagc
    42061 tgcttttact gtcatatcat agactaatcc atgaacagtc atttttaatc caccagctgc
    42121 actagaagtt gcaaacatat cattatactc tatatcatct acagataatt tattagctaa
    42181 atctttaata gcacctgata agccatttct tacatcgcca ccttcaaaca ctgttgttgg
    42241 agcttgacct tgacccaaaa atataggatt gttagtatta atatcgtgga aagcatttac
    42301 cactgtagta gtacttccaa tttcagctac caacacatct atttttaaag aaaccttgct
    42361 attttccatt atttattact catttctctt cttttttcaa ctaagaaagt ggctacatgt
    42421 atgcctttac tgtttcttcc aaatccagca tctatgcctt gttcaacagc tatttcaggt
    42481 gttacttgtg ttcctccaca cgcaatcatt actttatctc ttataccttt ttctacacaa
    42541 taatcgtgta attttttcat gtttttatag tgaatatcat catgacttat tattgtagat
    42601 gcaagtattg catctgcatt cagttcaatc gctgcatcta ccaatttttc tacaggtaca
    42661 gaagtcccta gatagtggca ttctatgcca tatttttcaa tacctccatg ttttatatct
    42721 attatttctc ttaaaccaac tgaatgttca tcttctccaa ccgtagctga aactattttc
    42781 ataggttttt cttctatatc tgctcttatt tcttcatcag ttagtacctt aggttcttct
    42841 ggtattacta aattgtttaa atctatatca aacggaactc ttcctttcac ttctattcta
    42901 gtcccttcag attcatgcat aacttctcta cttatgacct caatttcttg taagttcatt
    42961 tttttgacaa attccaaagc tgcaaactct gctgttcttt tatcagtagg aagcatcatt
    43021 gttatcatta caattccatc tgcacaccat tccatttcag gcttaatttt agttccattt
    43081 ctgtactcat atgattcttt tagtctattt tctacattat caaaatcgtc aagctcatca
    43141 atatatatta ttttgtctgg attttcaaat gtacatccat ctattaacat tgatggatta
    43201 tctatagcat tttcatcata ttgagctaca ttattgtatc caaagtgagc agttacaggt
    43261 gctaaataat cttcttctct ttcataaaca gtaccttcac caactccacc ttttattttt
    43321 ctagatattc catcaccatt tctttctgga taatttccag aatcaacaaa aaatccttgt
    43381 tccacagatt caaaatatcc accaacttca gatatttctt ccatatataa tacagctctt
    43441 tctttaagtt ctcttgcttt gtctcttaat tcacccacat ctttaagttc tatcatatcc
    43501 ataagcccat ccataccaac taaagcttgc tttgctgtat cacatgcttc tatattgtat
    43561 atatgccaag gtacatttct accttcatca ggtgttatag ttgattgtat gtcagctcta
    43621 gttaatactg atgttaataa gtttaataca tgagtaactg ttgcttctct agttgatgat
    43681 tccatatatt tagtattcat ttgagctctc atcttataat cactaaataa ctctctaagt
    43741 gcaacagcgt aaggtaagtc tatttttaaa catggtgctg gaggtgctgt tggtggaact
    43801 gttgataagc atatattact tttatctata cctatttttt ctgaaaatat agagtttaaa
    43861 gcgtgttgaa ccataagttc aggcattacc ttccatgctt ctctagcagt agcattagca
    43921 ttatgtgctc catcaatttg agctatattg gcaaaagcca ttattttctt tgcctcacaa
    43981 gcatctacaa aagaccttac catgtttata ttcctataca gaacattata ttgtgggtct
    44041 tgatgtgctc cattgactcc ttcctcagca aacattactg ctacttcagg accagcaaca
    44101 ccacttacat atgaatggta attaataggt ctaccaactt cttcttctat aaaatcaaga
    44161 gccttccttt gagctcttac ttgttttctt gttattggaa ctccacctat accttgtgga
    44221 gttccttcta taagcccatc aaaatgtgat tgtccagcag ttctgataac cattagatgg
    44281 tcagctccat gatgagctgc cattctcatt cttcttatat catcctcaaa tctaccagaa
    44341 gctatttcag tagtaataac tggacttggt tgagggtcta tattattgaa atacttagat
    44401 gatggtagcc ctacactctt ctttaaaggt tttgtacagt ctttatattt aaaaggtccc
    44461 atttcaagat tttccaagtg ttctctccaa acccaacctc ttcgttttgg tttatattta
    44521 tccaaatctt ttaatatata gtctatatcc aattttttat tttcctttaa catgattcta
    44581 ccccttctct aaataaacat gtaacttcat cccaatattc acccttaact aataacaaac
    44641 ctgcttctct aaccgttata tttttagatt tagccaattt ataaactaca tgccctgctc
    44701 ctttacctat aagacctctt tccataaccc cttctaaaat aggttttact tcaagagaag
    44761 aaaatcccat tctcaacaag acagaccttt ctattgatgg tgttgtattc tttttaccaa
    44821 gttctatcat tggttctact atctgggtag ctaaactcca aaacctttct tttaactcat
    44881 catcactcag ttcttgaaga tgttttcttc taacttcaaa atcatcctct ctttttttca
    44941 tgaacattcc tccattcgta ttgatttaat cgaattttct gaatttttat tttatattaa
    45001 attaaaaaac aataattact ataaattatt taatacatca acaacaaaat ctcttgaact
    45061 ttttacttct tccattaaaa attctatatc tcgattactt agcttatcaa tattatcaat
    45121 gtgattatta gatatacaat tttttataaa tgactttctt attttattca tatcaatatc
    45181 aacacatttc aataattctg gtctttctgg taatattaag tttactcctg caatttcttc
    45241 tcttggattt ccaaatttta tatctattcc attttctctt gcaaaagtaa gctgtggaca
    45301 tatatgttta cctgcgcctg tatattctgt ttcttgtacc actataactt tatcctcatc
    45361 taactcttga gctaaagaga atgctgctgc taaagatgta tttcctgctg gacctctttc
    45421 tataccttct agctgtgcca ataattcagt tgtataaaaa acttctcctt gttttactaa
    45481 tacatatcta tccatatatc taagtggtct agctgcagac ctaggtacat ctgacctatc
    45541 aggccatgta cagtatggta tcccaaaacc tgtatgtcct gttgtaaatg attttttatt
    45601 aaattgatta tcactagcca tgtgtaatcc ttttaaatct acacttgctc ctactacttt
    45661 agtattaata gaaccagctt ttatcaatcc tcttgcagtt ccagtaagat taccaccacc
    45721 tgcatttgta caaacaacta tatcagggtc ttttttatac ttttctctaa attggatagc
    45781 taactcataa cctaaagttt ctacacctgc aattccaaat ggtgaatata atgatgcgtt
    45841 aaaatagcct gtttcttcta ataaaactaa gaacgtataa aataactctg gtccaacagt
    45901 taactgaaca acttctgctc catatgcctc acattttcgt gctttttcta taatttcagg
    45961 ttgacctaca ccattagaat cataacattc ttgaactatt atacatttta atccctgcat
    46021 tgccgcttgt gatgctacag ctgcaccata gttaccacta gtagctgcta ttacaccttt
    46081 atatcccatt tgtttggcat gatatactgc agtagctgct cttcttgctt taaaactacc
    46141 agatgcattc attgcttcat cttttacaaa tattctagct cctttacctt ctttagcaca
    46201 ttttctagct aatttagtca aatttttaag ctctattaaa ggagtatttc caacagcata
    46261 ctgtgattga attgcttcaa tatcttgtaa tgtatatcct gtttcactca tcattttctc
    46321 ataatcaaac cctattccct cttgttcaaa ataagaataa tccaatccga ttgcattttt
    46381 cattatttcg ttatttcttc ccataacagc ttgataactc atatctttca ttgatgttga
    46441 attattcatt atatacacct ccaaataata tttctttagc ttggattcct atttggagta
    46501 actctggtat acatttacca taatcatgag tataatatgg atttatttta agtaaattac
    46561 cttttacaag tctgcctgta attgttttaa cttctactaa gtcgcctata gaagcatcac
    46621 tttgtataaa acctttaacc cacatttcta aggatacttt cttagtatcc tctggaactt
    46681 gtggagctct ttcttctgga gtcaatacta tattgtgtat aataacccaa tcattaattt
    46741 tagcatccat tttttcatcc ccttattaat tgactattgc cttactaatt aatttactgt
    46801 tattttaaat taaacattat tttaccaatt agctaactgt tatcttacta attagctagt
    46861 tgctatctta ctaattagtt agctgttatc ttactaatta gcctttgatt cttcttccaa
    46921 ttcaacttct atctgatttc ttatatctcc cattattgct ctaggtactg gtatatccaa
    46981 catagtttta agacctggtc tagcatttat tattaatgga atagagttta ctatcattgc
    47041 ataagtacct actcctccag gtatttcagg atttatttgt aaatcaatgt ttggtatacc
    47101 ttttattgat acatagtctc ctgttttaat accttctgct tctggtatta tctgttgtgg
    47161 atgctccatt tcaattaaaa cttctccatt tacatatcca tatccacatt gtctacaacc
    47221 agcaacattt ccagccaatg cctctccgta cttagatttt ctatctacta tagtcattat
    47281 tggctctttt gtttgttcta tcttatctaa tttccaacct aatccatcag ctatcatatt
    47341 tattgattct acaaaaccta catgacctgc tatagtctta tcttctacac cttttataaa
    47401 ttcttccctt gttactccaa caccttgttc ctccataaca gactttccaa atggagataa
    47461 atcatttact ctcttagctt ttatactagt aacttcttca caagtgcctg aaagcgccaa
    47521 tactagtaaa tctaatacaa atcctggatt tattcctgtt ccaagtatac ttactccatt
    47581 ttcctttgca acttcatcca tttttttagc taaatctgca tcatcagctt gtggatatgc
    47641 catttgttct gctgttgata taacatttat ttttctattt aataagaaaa ttattttatc
    47701 aaaagccttt ttagtaaatg aatcagttgc taacaaaaca acatctacac ttttttctct
    47761 aaaaacttct tcataatttt tattgataat aacttctggt ctttctcctc tttcaattcc
    47821 taaaacatta tacatacttt ttcctgaagt acttctacta caaacagata ctatttctat
    47881 accttctttc tttagaatca tattagccat acctattccc atagctccaa atccccatat
    47941 tcctactctt acttttctca tatatacacc ctcctaaaaa tttatatatt ctcaataatt
    48001 agttaaagca taaatcgtgc caactttaaa attaaagtaa atatttattg aaacgttgaa
    48061 actataatta ttttattatg tattttcata aataaaaaat aatatttctt atgagaaata
    48121 aaaaaaagag caaaatattt tgctctttta taataatttt gctcctctat tttgcttttt
    48181 tattttactt tgattttgtt tttttatctt gcttatttat aatattttga tattatattt
    48241 ttttatttta tactgtaaat tttgcctatt catacctaaa attgatgcag ctttagttat
    48301 attgtaagat gccttttcta atgattcata tatatacttt tcttctatct cactgataat
    48361 cttactaagt gttttgtcct ccaaatcgtt taaagaataa ttgttactct ctttattctc
    48421 tttaagattg taatagtcgt ttagattaat catacttgtt tctatttgta cctcatcttc
    48481 catcatactc atagtacaat aaattatgtt ttctagctct cttatgttac cttgccaatc
    48541 gtaatttttt aaaattttaa tagcttcatc tgaaattcct actacttttt tatttaactt
    48601 tttattatac tttgaaataa attttttgca caatagaggt atgtcctctt ttctatctct
    48661 aagaggagga atttttatat gaattatgtt aagcctataa tataaatctt ttcgcatttt
    48721 atgctcgttt aaaattacct ttggactttc atttgtcgtt gcaataattc ttacatctat
    48781 aggtatatcc ttagttcctc caacccttct tacataacct tcttgtaaaa cccttaatag
    48841 tttagcctgt aacataatag gcatggaatt tatctcatcc aataacaatg tccctttgtt
    48901 agcttgttca aataagcctg gcctatctat tgctcctgta aatcctccct tgctagttcc
    48961 aaaaagaata ccttcgaata gtgattccgg caaagctgca caattttgtg ctataaatgg
    49021 atagtttttc ctattacttc catagtgaat ggactggcta aataactctt tacccgttcc
    49081 agtttcaccg tatataaata ctgaagcatc agacttgcaa gctttcttag atttagctat
    49141 tgcttcttta atcaaattac tttcccctaa aatatcatca aattcataac cctttttttg
    49201 tctaatacta actttattga ctaaattttt tttataattt ctgtttagta aattttctat
    49261 cgttgtcata ttctttgata tctcaagtgc ccctacaaac tcgcctttaa tatcaattgg
    49321 tattgtagta ttaattgctg ttatctctct tccattttta tccagatatt tttgaatatt
    49381 gtctttgata acttcccttt tttccaaaac ttctaatagt gtactcctgt ttattttcat
    49441 tttgttgact atatcaaaaa atgaattggt taaaatatcg tgtctgttca ttttttccat
    49501 tttttgtaca gaattattgt agattatagt tttcccgtct ttattaacaa aatgtacccc
    49561 ttcatcaata ttttccaata tttcattcat tattttaaaa aatatctctt ggttcaacta
    49621 tatcacccca gtacctaaat atataaaaac ccaaaaaatt aataaaatgt tgctattgta
    49681 tttatcttat catatattta tgatattttt tatgtacatt atattaatat atttttaagt
    49741 atatttaaaa ttttatttat atatctttca ttatggtt
//
LOCUS       DAEHWO010000021        49060 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEHWO010000021 DAEHWO010000000
VERSION     DAEHWO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49060
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.021"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            2..841
                     /locus_tag="KNP54_001471"
     CDS             2..841
                     /locus_tag="KNP54_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010293327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0892377.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITKYLYFNGL
                     DGK"
     gene            956..1195
                     /locus_tag="KNP54_001472"
     CDS             956..1195
                     /locus_tag="KNP54_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892378.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1366..1542)
                     /locus_tag="KNP54_001473"
     CDS             complement(1366..1542)
                     /locus_tag="KNP54_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892379.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1596..1692)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2047..2721)
                     /locus_tag="KNP54_001474"
     CDS             complement(2047..2721)
                     /locus_tag="KNP54_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBF0892380.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(2941..3495)
                     /locus_tag="KNP54_001475"
     CDS             complement(2941..3495)
                     /locus_tag="KNP54_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBF0892381.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYYK"
     gene            complement(3573..3938)
                     /locus_tag="KNP54_001476"
     CDS             complement(3573..3938)
                     /locus_tag="KNP54_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892382.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4403..5188
                     /locus_tag="KNP54_001477"
     CDS             4403..5188
                     /locus_tag="KNP54_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0892383.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEGGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5285..6109)
                     /gene="pdaA"
                     /locus_tag="KNP54_001478"
     CDS             complement(5285..6109)
                     /gene="pdaA"
                     /locus_tag="KNP54_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBF0892384.1"
                     /translation="MKKDSLKKYIMIGAFALTLFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6330..9449
                     /locus_tag="KNP54_001479"
     CDS             6330..9449
                     /locus_tag="KNP54_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBF0892385.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANKIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINFIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9467..10066
                     /locus_tag="KNP54_001480"
     CDS             9467..10066
                     /locus_tag="KNP54_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBF0892386.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10293..12422)
                     /locus_tag="KNP54_001481"
     CDS             complement(10293..12422)
                     /locus_tag="KNP54_001481"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBF0892387.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12688..12936
                     /locus_tag="KNP54_001482"
     CDS             12688..12936
                     /locus_tag="KNP54_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892388.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13102..14493
                     /locus_tag="KNP54_001483"
     CDS             13102..14493
                     /locus_tag="KNP54_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBF0892389.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14608..16077
                     /locus_tag="KNP54_001484"
     CDS             14608..16077
                     /locus_tag="KNP54_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBF0892390.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16142..16735
                     /locus_tag="KNP54_001485"
     CDS             16142..16735
                     /locus_tag="KNP54_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBF0892391.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            16917..18263
                     /locus_tag="KNP54_001486"
     CDS             16917..18263
                     /locus_tag="KNP54_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBF0892392.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            18445..18816
                     /locus_tag="KNP54_001487"
     CDS             18445..18816
                     /locus_tag="KNP54_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBF0892393.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18809..19498
                     /locus_tag="KNP54_001488"
     CDS             18809..19498
                     /locus_tag="KNP54_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBF0892394.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20018..20884
                     /locus_tag="KNP54_001489"
     CDS             20018..20884
                     /locus_tag="KNP54_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBF0892395.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21126..21935
                     /locus_tag="KNP54_001490"
     CDS             21126..21935
                     /locus_tag="KNP54_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892396.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22079..23143
                     /locus_tag="KNP54_001491"
     CDS             22079..23143
                     /locus_tag="KNP54_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBF0892397.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23171..23890
                     /locus_tag="KNP54_001492"
     CDS             23171..23890
                     /locus_tag="KNP54_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBF0892398.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            23914..24498
                     /locus_tag="KNP54_001493"
     CDS             23914..24498
                     /locus_tag="KNP54_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBF0892399.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24500..25849
                     /gene="pabB"
                     /locus_tag="KNP54_001494"
     CDS             24500..25849
                     /gene="pabB"
                     /locus_tag="KNP54_001494"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBF0892400.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25839..26582
                     /locus_tag="KNP54_001495"
     CDS             25839..26582
                     /locus_tag="KNP54_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBF0892401.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDIKYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FVKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26616..27317
                     /locus_tag="KNP54_001496"
     CDS             26616..27317
                     /locus_tag="KNP54_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892402.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRNIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27343..27915
                     /gene="folE"
                     /locus_tag="KNP54_001497"
     CDS             27343..27915
                     /gene="folE"
                     /locus_tag="KNP54_001497"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBF0892403.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            27979..28770
                     /gene="folP"
                     /locus_tag="KNP54_001498"
     CDS             27979..28770
                     /gene="folP"
                     /locus_tag="KNP54_001498"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBF0892404.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28781..29146
                     /gene="folB"
                     /locus_tag="KNP54_001499"
     CDS             28781..29146
                     /gene="folB"
                     /locus_tag="KNP54_001499"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBF0892405.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            29139..29645
                     /gene="folK"
                     /locus_tag="KNP54_001500"
     CDS             29139..29645
                     /gene="folK"
                     /locus_tag="KNP54_001500"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBF0892406.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29626..30411
                     /gene="aroF"
                     /locus_tag="KNP54_001501"
     CDS             29626..30411
                     /gene="aroF"
                     /locus_tag="KNP54_001501"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBF0892407.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30666..32456
                     /locus_tag="KNP54_001502"
     CDS             30666..32456
                     /locus_tag="KNP54_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBF0892408.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32474..33640
                     /gene="rpoD"
                     /locus_tag="KNP54_001503"
     CDS             32474..33640
                     /gene="rpoD"
                     /locus_tag="KNP54_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBF0892409.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33805..34494
                     /locus_tag="KNP54_001504"
     CDS             33805..34494
                     /locus_tag="KNP54_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBF0892410.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34508..35605
                     /locus_tag="KNP54_001505"
     CDS             34508..35605
                     /locus_tag="KNP54_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBF0892411.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSTEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35668..36240
                     /locus_tag="KNP54_001506"
     CDS             35668..36240
                     /locus_tag="KNP54_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBF0892412.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(36300..36767)
                     /locus_tag="KNP54_001507"
     CDS             complement(36300..36767)
                     /locus_tag="KNP54_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBF0892413.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37153..37629)
                     /locus_tag="KNP54_001508"
     CDS             complement(37153..37629)
                     /locus_tag="KNP54_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBF0892414.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37749..38840)
                     /locus_tag="KNP54_001509"
     CDS             complement(37749..38840)
                     /locus_tag="KNP54_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBF0892415.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFIPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYAKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLLTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38833..39222)
                     /locus_tag="KNP54_001510"
     CDS             complement(38833..39222)
                     /locus_tag="KNP54_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0892416.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39414..39860
                     /locus_tag="KNP54_001511"
     CDS             39414..39860
                     /locus_tag="KNP54_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892417.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEELDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40124..40849
                     /locus_tag="KNP54_001512"
     CDS             40124..40849
                     /locus_tag="KNP54_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892418.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            40836..42080
                     /locus_tag="KNP54_001513"
     CDS             40836..42080
                     /locus_tag="KNP54_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0892419.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLIVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            42160..42837
                     /locus_tag="KNP54_001514"
     CDS             42160..42837
                     /locus_tag="KNP54_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892420.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQVSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42838..45399
                     /locus_tag="KNP54_001515"
     CDS             42838..45399
                     /locus_tag="KNP54_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892421.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVKNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIVCTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAIEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            45620..46894
                     /locus_tag="KNP54_001516"
     CDS             45620..46894
                     /locus_tag="KNP54_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBF0892422.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(47055..>49060)
                     /locus_tag="KNP54_001517"
     CDS             complement(47055..>49060)
                     /locus_tag="KNP54_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBF0892423.1"
                     /translation="FNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLN
                     EIIGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVND
                     NGTLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPG
                     LGQTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLAL
                     SDETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSED
                     SITNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYS
                     LVTKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWEN
                     AENAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGG
                     EASINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLAD
                     AVSIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQN
                     PQRISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSP
                     VMLVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
BASE COUNT        19700 a         5150 c         8180 g        16030 t
ORIGIN      
        1 aatgaaagat tactataaaa taggagagat atctaaaata tatggaatag gtagagattc
       61 attaatgtat tatgaagaaa taggcattct aagaccagtt agagatataa atggatatag
      121 aatgtataat atatcagata tatggaaatt aaatttaata aaagaattta gaagcttgaa
      181 ctttccaatg aagaaaataa aagaatacct agatgacaga agtatagagt ctacgaaaaa
      241 tattttaaat gaagaactcg atttaattga taaaaaaata gctgaattta taagccataa
      301 ggaaaatatt ataaaaagat tgagttcaat tgaaagtgta attcaaaata caaaaataga
      361 tgagatagag gttgtatata tagaaaaaag aaaagcttta gaattaaatg ctgatataaa
      421 gagggatgaa gacttcgatt ttttaattca aaaacttcag aaagaatatg aagatagatt
      481 taatatactt ggaaacaaca atattggttc tgccttttct actgaagcaa ttaataaagg
      541 catatttaat gagtttaaat ctgtattttg ttttctggaa agtaatgaga aagtatataa
      601 tatagttttt gatgaaggat attatgtaac tttaaattat actgggagta attctaataa
      661 taagatgtat atggagaagg tgtttaaatt tatagaagaa aataattata agataattgc
      721 tgaccctata gaaatctata agatagatat acatgagact ggaattgtag aggagtttgt
      781 aacagaaatt caagttccta taactaaata tctatatttc aatggattag atggtaaata
      841 gaatgaaaaa atgttgattt ggcaccgatt tgccactgtg ttataaaatc ggtagcaaat
      901 tatattttaa attataagat agcatgaaaa aataattgtt tagggggtta taaatgtgaa
      961 atgttctaat tgtggaagtg taaatattga aaagggaatt ttaacaactg gtggcatata
     1021 tgctgaaact attggattaa aatatagagg agatggaaaa ttagataaag ttataaataa
     1081 aacttttcca gtacaatcta ctatatattc agatttatgt ttagattgtg gcgaaatagt
     1141 tagaacctat ataaaggata atactgatag gaattggtgt aaagataaga aatagaataa
     1201 tttttgaagt tgaattttat taaagataca agtgaaaaag tataaatggg aagaaattgt
     1261 tatatggaag aaaactttgc atatatggaa gattagtttt ttaatataat aacattttta
     1321 aatgtagata aaactaaaaa gggttctcta gaaaacaatt tctatttaat tatacttact
     1381 taccaatacc atcacttgat gtaaacaaga ttctactaca ttttctccgt actctagtat
     1441 aaaatcatct agctgtgtat ctataaaatc acaataatca tataaactac taatataagc
     1501 agttaacatg tgtgtacatt tatccatttc atctctaaac atatatatta ctatccccct
     1561 aaaaaacttt cataaaacaa aaagaacaat atctttttgg caactggctg acataactca
     1621 tagtttattt tataagcgtt agtccctata gctttgcgtc actaaatttc tctagttttg
     1681 ccgatttagt tttattctac aactaaaata atacactagg ataagttatt gttcaacata
     1741 cttgtcagaa aattgaaata tttaacaata tcttaacaat atgaaatcta tttttcactc
     1801 aagaaacaaa ctatatgtat agaatgttta ataaaaatta tatttagttt tgtattgaag
     1861 tttttgtatt aaaaagttta gttcacaagg gttacttggc tagataatag ataaacaaaa
     1921 atatcttgaa aaaatatata tgaatggcaa aaaacaaggg atgaatttta tatagactca
     1981 tcccttaatt atttatatat tgaccttgat taaatatatt attattttta agcttcaatt
     2041 tttatattat atttctaaag tttctataag aggattatcg ctaaataatt ttaataaatt
     2101 tgttttttta tatcctttag gtaacttagt atatataact acttctaacc aatccccatc
     2161 aaggcgttta atattcatgt ttataatttc aatattagat tttttaaatt taccttcaat
     2221 atattctatg gaatcagtgc tgttagaaat tttaagagaa acttgctctg ctgtagggag
     2281 tttcatccat ttcctatctc tatgaagtgt tatctgtaca ataacaataa tgatacttga
     2341 aacaatacca actaagtata atccagagcc aatggcaaga cctgtaccgg ctgttgccca
     2401 tataccagca gctgtagtaa gaccacttac tgattgattt ctaataaata ttaatccagc
     2461 acctaaaaaa cctataccac tgacaacttg tgctgcaacg cgggctgggt ctagaccaat
     2521 acctggagta cccactatat cattaaatcc atacttggaa acaatgatta taagtgctga
     2581 agctaatgcc actataaaat gagtgcgtat tccagcttct tttagtctat tctttctctc
     2641 atatccaatt aaagccccac agaaaccagc agtaatgatt cttgctatat attcaaattg
     2701 aatcaatata tgatggttca tttatctagc acccccttct atataatatt atatatacta
     2761 taatactaca ttttttatgt gaatatagta aagtttaaaa tttatataat agttatatat
     2821 gaatataaaa tgtataaacg tatattatgt atataaaaat gatagaaagc atctaatttt
     2881 aaatgattaa agagcaagct taaataaatc aaacttgctc ttttaacata gtgtatgttt
     2941 ttatttgtaa tagttagata aaaatttatc tgtgtttttt acatctgcaa aactgttctg
     3001 tagtgatgcc atgaatactt gatgtacagt atttgcatta atttctatat tattccaaga
     3061 taaattcttc gttgtacatg catcgcttat tagagttatg tcgtatcgaa gtttctttgc
     3121 tgttcttaca cttgtatcaa tacacatatg gctcatcatt ccacagatta ctagattagt
     3181 aatatttttt ttctcaagga tactttgcaa atctgtttca aagaaactat ctggtgtgtg
     3241 tttaattata atttcttcat tatctagtgg aaaaacaatt ttatttattt ctgaaccatg
     3301 agtattagga agaaaaaaag aagctgtttt atctgttgat atatgctgta tatgaataac
     3361 tggtaaattg ttttttctaa aaaacagtag tattttttta gcattttcag cagtttcttc
     3421 tgattgaaat aattcacatt ttccattttt aaaataatca ttttgaatat caatcaatat
     3481 taaagctata gacatgatta tacctcctat ttatttttat tataatacta ttgtaaaaaa
     3541 tgtaaattac ttactttttg gtatgtatag gattacttat tgtagcaaat tcctttatta
     3601 tctagaattt cttgttgacc atgttcaagc atatattcga ttcctatttc ttgcattatt
     3661 tccactgctt ttaacatttt tttaccacga ttagtaagaa aatattcaac atgtaatgga
     3721 tatccagcag aacttatttt atcaataatc ccaaaatcac gtaactcttt taattgttga
     3781 atcaacattt tttgatttat tccataaata ttatgttgca attcagaaaa tgttttatta
     3841 gattgtctta attcaaatat aaggatagtt ttccattttc ctttgattat gtcatgtaca
     3901 atttcaagag gacatgtata ttcagctctt attttcatag catatcaccc ccagtaaaat
     3961 gataataaat tatatcactt gtcttgtgat atgacaaata tatatgaact gtatataaat
     4021 tttatgtttt attaagttct aaatttcttc tattgtagtt catatttagt acataaataa
     4081 ttagtaagat ataagtaaat aaatatataa catgactata gaaatttaac tttaaaataa
     4141 cttatgataa tttagaggag gaatatatat gaatatatca agaaaagcta tgaaaataat
     4201 agaattagca caaaaaattg caaataagag aggtatttca gtagaagaag cttggagtga
     4261 agcagtaaca gaatataaaa ataaatacga acatattgca tagatattta aaaatttaga
     4321 atatttggta gaatataatg attttaaatg atactataaa ttataaggta tatcattatt
     4381 aacatagaag gaggatatct gcttgattgt aaaaatagat aatactttag aaaaagaatt
     4441 ttggcaatat gtatcacatg aagaaagttt aaatttattc ataattggat acgttgagaa
     4501 ttatggattt agctctcaat atcaagatat atggtctcag gtagaaggtg gaaatataac
     4561 ctctataata ttaaaaaata agtcaacact tataatttat agttttaaaa ataattttaa
     4621 tataggagaa atgaagaatc atataaaaga tttagatgta gaaagcataa gtggaaaaaa
     4681 atgtgtaata gatagactaa taagtaaata caaagatttt tatgaaaaac tagataataa
     4741 attttgtgta ttaaaagaaa taaaagaaat agatttttcc aacatgaagg agtataaaat
     4801 agaaaatgct caggaaaaag atattgatga aataggaaaa cttttaaata ggtcagacta
     4861 taaagtaagt aaaaattaca tagaagaaag aaaagttcat ttaaaagagg gaaatgtaag
     4921 agcatatttt attagaaatg atgatactat gattagcact gtgtcaactg gtatggaaac
     4981 tagttttttg gcaatggtgg tctctgtaag tacagataaa agatataggg gaaaaggact
     5041 tgcaagttat atggtttaca atttgagtaa agaattgttg ttagaaggaa aagttccatg
     5101 tcttttttat aataatgatg tagcaggtaa aatatatcat aatataggat acaaagagat
     5161 aaatgaatgg acaattcttt ttaaatagct ataaaaaata aaaaactcta tcgagaatta
     5221 aagtatttat aaataactat atttttacta taattcatga tagagttttt ttaaatttat
     5281 gatactattt tttattattt aaataatcaa gtgttttaag tttataacct tctttttccc
     5341 aatgtgtaag aacctcatct aatatctcag tatttgttga tgaatttgga tgcagtaaaa
     5401 ctattgcacc aggatgagtt cttgaataaa ttttgttttt ggcaaattca tgagtaggtt
     5461 gtttcttttc ataccaatct acataagcaa aactccaaaa tattgattta tatcctaaat
     5521 cttgtgtata ttttaaagat tgttcgctaa atttacccat tggaggtcta aaatacttag
     5581 gcatttcttt tccagtaaca tctttgtatg ctttttctac acttgtaatt tcttctttga
     5641 atttttcaaa atctgtaata cctgccattg atggatggct ttttgaatga ttacaaacta
     5701 aatgtccttc tttttccata cgctttatta actctggatt gctttttata taactttcaa
     5761 ctacgaaaaa ttgagcttta gcattgtgtt ttttaagcgt atctaataat tttggagtgt
     5821 ttccactttc atatccagca tcaaatgata gatatataac tttttcattg ggatttccta
     5881 cataataagc tccgtatttt ttaaaaaaat cagcttcttt tataggtgat ggctgtttac
     5941 catcttccct agggttaaaa taccaatcat attcatgtgt gtcgagtgtt ggactagaaa
     6001 tttgagtttt tgttttatct aatgatttaa aatttatact agcaattcca aaaagtgtta
     6061 gagcaaatgc tcctatcata atgtattttt ttaggctatc ttttttcaca atttcacctc
     6121 ttatttaaaa tttaaagtat atttcttata atatagtttg aatatttata gttaaaaata
     6181 ttcacatata caaataataa atgaaagaag tttactgtaa gatataaagt tgatattaat
     6241 tatcttaaat aaagtgtata taaatgataa aatataaaga gaaatgattg taaataagtt
     6301 aggctggttt aacttgaagg gatataaaaa tggataatat aataagtgta ttgaatgatg
     6361 ttgttttttt agatatagaa gttagtggat tagattgttt aaattcagaa attttagaag
     6421 ttggagctgt caaggttaaa gactggaaaa tatataccta tgaatcatta ataaaaaaca
     6481 aatttgaggt acctatagaa gtattctcag tatgtaaaaa tttagataaa aatgatttag
     6541 aaatagctaa taaaatagaa ctggtggaag atagacttgt aaattttgta gaagatagtt
     6601 tcattatatg tcatgattta agtctgaaaa aaaagttttt tgagtatcat atgccaaagt
     6661 taaaaaataa atttattgat ttaattgaat tagcagttat tttagaacca tatcataaag
     6721 attatagctt agaatactta aaaaatactt taacaaattg taattctaaa gtggaaaata
     6781 gagctttatc agatgctatt gatataataa atattgtaaa ttgcctttta gtaaaattta
     6841 ataactatga aaaaactact ttggagccat tgagttttaa aataaattca tatcttaaaa
     6901 aatttaatct tccaacatgg gaatggagca aatttttaga agaggcaaat tatgatttat
     6961 caaataatat aaatataaaa aaagaatata atatatttga ctcaaaagaa gaaaagaaga
     7021 aggaaagaga aaccttaaaa attttaaatg aagaagaaaa aaattatgaa gaattattaa
     7081 aatacaaaac tatttgggag aataaagaag gatttacata tgaatataga cctggtcaat
     7141 atgagcttac taaaacaata agagagttgt ttagaaatag cgaagatgaa gaaaaaattg
     7201 catgtataga ggcaccaact ggtataggta aaagtgtagg atatttattg cctgcaatat
     7261 tagaggctag aattaataaa aaaagattat taatttctac tgacacaaag gaattgcaga
     7321 tacaattaat aaataaagat attccaaatg tgttagattc tttgggtcta aatggaaaag
     7381 taagttacgg atatataaag ggaaaaaata actatatttg tatagataga ctggaagcat
     7441 atatagatga ttatgagtct caaaacccta ctaaaggaga aattttatct ttaatatttt
     7501 tgaagagatt agttgaaggt ggcaagtatg gagatataga agaaataaat tatttagtgt
     7561 ttgacaactt caaggaaata agtactcact taagaaatgt aagttgtgac ccaaatatgt
     7621 gcagacctaa aaaatgcaaa aaagattgtt tatataaaaa cagaatagaa gaattaaaag
     7681 aagaacatat aacagtagta aatcattcac tattagctaa atggccgtat aaggatgaaa
     7741 aacctttaga aaatataata gtagatgaag cacataattt gactgaaaaa ggatatgatt
     7801 tcttttcaag tattataaat tcaaagtctt taaggtactt attacaagaa atttatcctt
     7861 acgagtttat tcaaaatagt agctttatat ataaaaaata tagtagaaat atgagaaaaa
     7921 taaaggcttt tgataaattt tataatgtat taaaaattgg aagagaagat aaacaaaaaa
     7981 ttgctagaag tataaatttc attattgaag agatagattc aatattaaag tttggtaatt
     8041 gtaatgaata taataatgta agtaattata atttaagatg ggaactgaat ttgcaaatag
     8101 atgaaattgt gggaaaacta aaaaaagatg gtatagatac tgaaataagt tatagagcct
     8161 atagtgaaaa gataaagttg agttgtgaga aaataataaa aaatttagtt tcaataataa
     8221 taataattta taggaatatt gatgatgata gtatagataa agaagcagat atatataaat
     8281 ttggaaaggc aaagacaaga gatttagagg atataaagat tatatttgaa atctttttag
     8341 agtatgatga aaaggatgat tatgcaagga tagttgaaat tgataagaat tataatgact
     8401 ttgaatttcg agtagtacca ttaaaaatag cagatttatt tgaagaaaat attttatctc
     8461 aattagaaaa aggaatattt ttatcagcaa ctttgagttt atctgaaagt atgtcttatt
     8521 ttaaaaatac attaggaata gacagagtta agaatgtgga aaagattata gaaccaattt
     8581 ttgattataa aaatagagtc tctgtagttg gattttctga tatttgtgag tacagaaatt
     8641 ctgaatttcc aaatgagatg agtaaaatta tatctaatat atcaaagatt acagaaggtc
     8701 atacattagc tctttttaat agtaaagata gacaagaaaa aacttatgaa atattgaaaa
     8761 aatacttaca tagttttaac ttagaaattt atgctgataa aaagggcatt agacacctta
     8821 acgatttaaa tagaaaatgt gtagtacttg gctcaaaagg atgttttgaa ggcgtagaca
     8881 ttccagggga tggtttggtt tgtgtaactt tagacaagct tccgaatcta aatcctaaag
     8941 accctttgta ttttactata atgaagaagt atggtataga ctactatact ataaattatc
     9001 ctcaaatgac cataaaggta aagcaagcta tggggagaat tttaagaagc aaatatgact
     9061 atggatgttt tgtgattttt gatgtaggaa ctaatataag tgtgttaaag agattagaga
     9121 aagatttaca cgattgtaaa atttcaaagg ttaatagcaa tgagttttat acttatataa
     9181 ggcgacattt aaataaatct agaagtttaa tactaaaatc tgttatattt gatactataa
     9241 aagcgttgaa tgttgatgct aaaatggata acaatgatgt tgataaggat attataaaaa
     9301 aagatataaa tgaaaatata agacaaagag ctgtaaaagg agaagtgtac catattgata
     9361 ttataaaaaa agatatgaaa gtaaaatatt ttgatagaaa ctatcttata aatttagata
     9421 tatttatgag agaagaagat aaaaattaag agtgggagtg atatatttgg caaaacaaaa
     9481 gttttatgct gtgaaaaaag gtaaaaatat aggtgtatat aatacatggg atgagtgcaa
     9541 aaaacaagta aatggattct caggagctga atataagagt ttttctactt ttcaagaagc
     9601 taaagaatat attgatgggt cagaaaaatt gagttttcaa gaagataagg agtttataga
     9661 agcatatgta gatggaagtt atgaacattc agtaaaaatg tatggttcgg gtgttgtgat
     9721 tttaaaaaat aatgaagtta taaaaactta tagtgaaaaa ggaaaagaga aaactttagt
     9781 aagtatgaga aatgtagctg gagagataga ggcttctaaa attgcaatgc agtactgtat
     9841 tgacaataat gttcaaaact tgattttata ctttgactat gaagggattg aaaagtggtg
     9901 tactggagtt tggaaaacaa ataaagaagg aactatagca tataaaaatt tctatgacag
     9961 tattaagaat aagcttaatg taaaatttac aaaggttaaa gctcattctg gaaataagta
    10021 taatgaggaa gctgataaat tagctaaaaa agctattggt gtataataaa aaaatattta
    10081 tacataatta catggtataa gagtatatct aaattcctac tttataatta aacaacttgt
    10141 aattaaataa attttgatta aaaaagcaga ttgtattatg aaaaaataag tatctaattt
    10201 ataaacaatt aataatagta ttaattagat acaacttatt taatataata aaatctgctt
    10261 tttatataac tataaaattt tactacattc tattagaatt gcccataaat accttcaagt
    10321 tcttctttta atacttcagg gtcatttata ccaatagaca tggttctagc cagtatattt
    10381 gcttggtcat aagttgatgt ccatgagaat acaccaccta gacaatttct aagaacatat
    10441 tgagttttta agaatattga taaagcatca tcatatgaca ttgcaaaatc tccatcctta
    10501 actaaatacg gaacttgagc agtattatca aatctatatt catatccatt tttatttata
    10561 taatcccttc taagctcatc ataagttctt gttatagtag cacctaatct tccataaaat
    10621 ggtataccaa gaaggatttt ttcagaaggc attccagcat tctcaagatt tcttaccatt
    10681 gcatcaacac tatatcctgg caaagataag tctgaatcaa aaagatttgc ttgatgtttt
    10741 ctaccatttg ggcctgtttc acctgctgta aaatcataac tcataagatt aaaataatct
    10801 attataggag ctattttatc tatttcagca cttgaattta tatatcctct atctcctgtt
    10861 ccagctacac taagccattt atcatctcct ataacatctc ttatggcagt tagtaagagt
    10921 gtaaagtttt ctctatcttg aggtcttgat gttattccag atgcactact tccaggatat
    10981 tcccagtcta tatctattcc atctaaagca tattcattta tcatctgatt gacctgtctt
    11041 gcaaaattat atctagatgt aggtgttaat gctgcatcag agaatccttc agctccccaa
    11101 cctccaatag ctacaattac ttttaagcta ggtttttcac ctttaagagc aagtaattga
    11161 tttaaaaatc taggataagg aataaacaaa tttccagact ggtctatctc agcaaaagca
    11221 aatataactg catctaatag ttgagcatct acattagttg gatttccaag aacatattct
    11281 gctacaattg gatttatatc tggacagttt gcattttcaa ctattggatt gtatgggtct
    11341 gttatttgtg gtctaactaa ttttttagaa tcttttaaag ttttcatagc tattttttta
    11401 gtattttttt cgctagtata atcgtagttt ttataattat gtttatagaa atcttcataa
    11461 ctactatctt ctttgttata gctagaattt attttgtcac aagattcatc tttatcatag
    11521 ttaaaattca tttcatcaca agacttatct ttaaacttat cttgtttgga gttgtgaact
    11581 ttgttagtat ttttagtatg ttttttctca tgattgcaat catctttaat atcagtcttg
    11641 tgttcttgtt tacagtcaag agctttgttc aggtagtcat gatgttcatg ttcacagtta
    11701 cattcatttt caatgttttt agtatgttct tttttccagc tacaagtatt atcaattttc
    11761 ttgctcactt cttcatcatt ataattatct ggtacaaaac ataagtacca gtccatacat
    11821 gaatatttct tattacaact gttaactcta ttttttaatt ccttatagtt tttaggataa
    11881 ggtaaaatca ctggcattcc aggaaaccag tttgcaggag taactatatt atctctatca
    11941 ctagtctgaa gtgcatctac tattctaagt atttctggaa tatttcttcc tgtagttagt
    12001 ggataataaa gaatcgttct tagaatttga ttattatcta taataaatac agagcgaaca
    12061 gttgatgtat cactcattgg ttttgatatc atgccgtata acttggcaat tctcatatct
    12121 ctatcttcta taataggaaa tggaatttct acacctgtaa gtaaagaaat attatacatc
    12181 caagctaaat gtgaactgtt actatcaaca cttagaccaa ttagttctgt atttcttttt
    12241 ttaaattcgt cataatattt agcaaaacat aaaaattctg tagtacaaac tggtgtaaaa
    12301 tcaccaggat gtgaaaataa aacaatccaa ttacccttat agtcagagag tctaatagga
    12361 ccatttgttg tattggcttt aaaatcagga gcctttgacc ctaaacttgg caaatttggc
    12421 atgtaaatca cccctcaata aattatcatt tattttattc tattaattaa tacatattag
    12481 tgttactatt ttattaaaag ttaagtaatc cttatgtcaa aaaaagatat ttattaaaaa
    12541 gatttaatat tttcctaata taaatgacaa tagtaattgc tattttttta ctaatttggt
    12601 atagtaatgg ataaggggta gtgtcaattt tagtgattat acgaggtgag tggattgaaa
    12661 aaaattctaa gaattttagt tatctccatg atgatatgtt ttgcaatgac ttttgcatta
    12721 gtgttaataa attcagttat gggagtacat ataggattgg attattactt tttgatggga
    12781 agtgtgctta cagtttgttt aacaattgga attgttttat gcaatgctag aaaaatattt
    12841 gatagcaaag ctatacacaa gacaagaacg aaaactgtca gtaataataa aaaacaaaag
    12901 agtcattcta gggatataaa aagaaagata tcataattta tgtaaaggaa atatttatgt
    12961 ataaaataat gattgatagg taaaataaaa acacgattta acttgtgttt ttattttttt
    13021 tcaagaatta tgatataata accaataaga aatttagttt accataaaat ataaagatta
    13081 ttaaatggag agggaactat aatgaatttt agagatttat ttgagaaggc tgtagatttt
    13141 attgatgaaa aaaggaaatc tatagttgcg atttcattat caacattagg tgtaattgct
    13201 ttgataatag tatttttctt aagtagtaac gagtttagtg taggaaatga agctaatgag
    13261 ttgttaaaga ttatagagaa aagacagtat tctatagctg ttgattacta cacaagtata
    13321 gaaaaaaagt tttctgattc aaaaatggaa aggtttaata agtctgtttc taaaaaaata
    13381 aataaattgc tattaaatag tggtgataaa tatttagatg gagacataag tcaagaaagt
    13441 tttattggat taataaatac cgtgaaagaa ttaaacaaaa taagtataga tgtggatgac
    13501 ttattagctc aagctgatag agttagagaa atgtataaag aagaaaatac tacttatgat
    13561 attgccatta actacataag tactgtttca atattaaatg gtatgggtag taacctagat
    13621 gtatacaaac agaatataga aacaatcaaa gagtctagag atgtttatga ctcagcagta
    13681 aaagaccaaa aagcatataa gtattatgaa gctattgaaa agtataataa agtattaaaa
    13741 gaagatgaaa agtattacag tatggctcaa aatgggaaag aacaatgtat tgaagaaatg
    13801 tatgattact atataagtag agctgaagag gcaaatactt ctggagatta tgaaagagca
    13861 ttacaatata ttgagtattt aaaagacgat tattcagatg atgaaaaggt acagagttta
    13921 gaaaaaaaat ataaaaagaa tttatcattg tatactttaa catctgatga cattataaat
    13981 gtaatagcta aaaaaagtgg caaagacaag gcaaatctat ctataaattc acttccacaa
    14041 atgataaaaa ataataaata ctattatgct gaagtatatg agtatgataa attaataaat
    14101 gaagttttgg taagtgcaaa aactaaagat ttatattcat ataaagatgg taaaaaagat
    14161 tacaaagtag attatggtga tggatacttt agaatattag aagatggaag ttatcaattt
    14221 ggtattacaa aagataaagc taagtttgtg ttaactaata ctcttgatga aaaagaaaat
    14281 aagtataaaa agattgagat attagatata gagaaagcag atagatatgt aaaaagtaaa
    14341 aagagtttag aagaattgtt tggaaaatat aaaaatattt attattatgc tgtagtaaat
    14401 aaaggcttat ttagaggcaa agaagtttat gctattaata tttacaatga aaaaatatat
    14461 gccatatcag aaaatggact aaatgaatat taattaataa tattaaatta atatataatt
    14521 aaaaagtttt tggggtttta aggcgcatta tgtagtaata taataatagg gatatataaa
    14581 taattttatt gtaaggagaa gtatgggatg agtaatgtga acaaaaagct agttatagct
    14641 attggagctg tagcattagt agtaataatt tttataggca taatgtgcat gcaatttaaa
    14701 ggggagaaaa tagcaaaaaa cacatatgtt aatggagtaa atattggaaa attaactaaa
    14761 tcacaagcaa aacaggaatt agctaaaaaa tacaaattag agaatgttga ttttaattac
    14821 aatgataaaa gctggaaagt aaagagcaaa gatttaaatt tatctactga cctggataaa
    14881 acagtagaaa acgcatataa tttaaataga aagagtgctt tctttggcaa tctatcaaaa
    14941 actatttcag caaattttgg caaaaaaagc aacttagtag ttgcgataaa ttatgataaa
    15001 aataaattaa aagcagaaat ggaaaagata gctaaagaaa tagatgtaga tgtaaaagat
    15061 gctacacttg atataagtgg tgaaaaagtc aaggttatac cagattctga tggtcttaaa
    15121 atggatattt ctaagagtat ggagaatttt gataatcaaa ctaaaaaagg taactataaa
    15181 aatgagttag tagtaaaagc tactccagca aaagtaaaaa aagagcaact tgctaatata
    15241 gatacaaatt taggtacgta ttcaacaaca tttaaaactt ctcaaataaa tagaagtata
    15301 aacataaaat tagcaacaga taatataagt aatgtattac ttatgccagg agaaactttc
    15361 tcatttaata aacatacagg gaaaagaagt aaggaaaatg gatataaaag tgcacctgta
    15421 ataatggaag gtgagatgga agaagattat ggtggaggag tttgtcaagt ttcatctacg
    15481 ttatacaatt ctgtgctata cgcaggttta gaaattgtta atgtaaaaaa tcatactata
    15541 ccatcaagtt atgttccaaa aggaagagat gcaactgttg cagatagtgg aatagatttc
    15601 ttatttaaaa ataatctaaa gcatccagtt tacataaaaa attacgtttc aggaaatcaa
    15661 attgtttgca atatatatgg aagtgcagaa gataaacaaa atataacaat atcaacaaaa
    15721 ttagatggcg tttcacaaac tacaatgaaa agagttaatg accctacaat gcctaaaggt
    15781 aaagaaaaag tagacaaaag tggaagaaat gcatattctg tatcaacata tagaacattt
    15841 aatgatgcaa atggtaaaaa aattaaaact gaaaaaatag ctaattcata ttatcctaag
    15901 aaggaaggta ttatattagt tgggactatg gaaccaaaac cagaggaaaa accaaataca
    15961 gacgaaaata agaataatca aaatacaaac aatcaaaacc caaataatca acaaaaacca
    16021 gaaacaccac caactgataa taagcctaat gagacacaac cacaaccgca agcttaaagt
    16081 tctcaagaat aggatttatg tagagtaata aaaaatataa atctaaatag gagggattac
    16141 tttgaattta aataatataa cgaattacgt tcaaagtatt tgcgagaata tttctaatgt
    16201 cttggatgta gatgttactt tagttacaaa agatttaact aggatagcag gtacaggaat
    16261 attcagaggt aaaataggag agacaatatc agagaagtca gtgtactctc ttgttttaaa
    16321 agatgggaaa tcctatgtta taaataaaga aatagaagag aactgtaata aatgtgcaaa
    16381 tagagaaaat tgtaaagagt tagctgatat atgtactccc gttaaaatgg gagagcatat
    16441 acttggaatc ttgggtatag ctgcgtttaa tgaagaacaa aaagaaaaga tactttcaaa
    16501 agataaggag ttaactgctt ttgtaaggag tatgtctgat ttaatatctt ttaaactaga
    16561 tgaactttat aaacaagaag ttaagactat agatgacctt gagagggaag ctatagaaaa
    16621 tgccataaag aaatatggaa gtaatacaga aggtatgaaa aaagtagctg aggcattaaa
    16681 tataggtata gctacactct atagaaaagt aaaaaaattc aacattaaaa gttaatagta
    16741 ttgaaaaaga ggtaaccttt ttatgaaaag aagaggatta ccttttttat tatgagaatg
    16801 gtggaaaaat atgtatagtt ttgacttgac atattaaata tgttatctta aatatatatt
    16861 ttagagtgga ggtgagtatt attttagtta aagatataaa acaagacata gaaagcatgc
    16921 ctagaaaaat tttagatata tctttgatag aagataataa aagtgatttg acttttttta
    16981 atatagaaga agaagacggt gatgaaacat taaaagcatt aaaacagagt tatgtgacta
    17041 caaattataa agaagaaact ctattaaact tgcaaggagc tttaaattca aagtcagata
    17101 caacgtctaa ggagttaaaa ttagaatcat ataaaagata taacaatgca ttggatttag
    17161 catataaaaa ttatataact agtgccatta atatggttaa taaagctctg gagataaatc
    17221 ctaaagacat tgatatacta aatcttagag gtcttttaaa attattaaaa tgtgattttg
    17281 ctaaatcatt tgagagtttt tatactgctt tatgttatga aaataatcat atatctagaa
    17341 aatatgtaaa tctaatttca tctgaagatt ttaaaacttt tttaggaaga tacaatcatt
    17401 ctataagatt tataaatgaa gaattaaatt atgagtcaat acatatttta gagaacataa
    17461 ttgaagaaga acctgaacta atagagccat atgtaatttt atctttgtta tatgataaac
    17521 taggtaatgt aaaaaagaga gaaggatatt tagacaaact taaagagcta gataaagata
    17581 atcctgtatt tgaaaaaaat gaagaagaaa aagaagatac aagtaaaaag gaagaaataa
    17641 aaaaagtaaa aagaaagaaa agtattttgc catatattat agttggctgt gttttaatag
    17701 gtatggggat atatttgatt caaagcaaaa agagaataga aaacttgaat aaccaaataa
    17761 gtagtaaaga ggaaaagtta agtgaaactg ataaaaagtt aggagaaacg agtaaaaaat
    17821 tagaaaaaac gaataaggaa ttaaatgagg ttaaaaataa agaaccagaa agagagataa
    17881 ctgtagctga tgaggaagat ttatattatc aagctctaaa tttaaagaaa aacaaagaat
    17941 atgaaaaagc catagataat tttaaaagtg tagtttcttc tggtaaaact aaaaaatata
    18001 tttctgagtc aatatatcaa ttagcaataa caaataaatt attaggaaat aaggatgaag
    18061 ctataaaata ttacaaaaaa tatataaata cttatactaa aaatgaccag tattatgatg
    18121 attcatatta cgagttgggt atgctttatt atgataatgg cgatttaaaa aatgcacaac
    18181 agacttttta tagtttgaga agtgaagttc cagacagtat gtataacaat tcaaaaataa
    18241 aagaaatttt aagtgaaaaa taggtttata tagttaagtt ttttgaaaca accaagtatg
    18301 tattttatta aattaaaata aaaataaatt taaaaagaga ttgtgtcaaa ttataacttt
    18361 ctattttaaa gaaagatatt tgcttgttga taaaactaca aatatatgat ttgaagcaat
    18421 ctctttaatt tttggaggtg gaaaatgaaa gttttcaatc aattggtaat aattttatct
    18481 atctgggtaa taggagagta tataagttcc tttatacaag gaattatact tattcctggg
    18541 agtatagttg gtatgctatt attatttcta ctactacaat ttaaagtttt agacttgagt
    18601 agtatagaaa atgtaagtgg atttttcctc gataatatgg ctatattttt tattccagca
    18661 ggtgtatcac ttataaagtc attagaccta ataagggaaa atgtattagt gcttttatta
    18721 gtcatatgtt taagtacact aatagtaatg tatactactg gaattattgt ggagaaaatg
    18781 ataaaaaaga aggaagaagg acaaaaaaat gtataatgta ttacagacac cagtatttgg
    18841 tataatagta acaatagttt ttttcaattt aggaagatac attcaacgaa aaacaagtaa
    18901 tcctatatgt aaccctttat taattgcaat cgtaggaata atattgtttt taagcatatc
    18961 taaaatccct tatgagaatt acaagatagg agctgatagt ctaaatttct ttttaggtcc
    19021 tgtcacagta gtacttgcag ttccacttta taaacaattt gaattattta aaaagcatat
    19081 gtttgagatt attgtaggaa taggttgtgg tatagtgatt tcttttgtat ctgtattgat
    19141 aattggcaaa atagctaatt cagatgtaag tataataaat tcactaattc caaaatctat
    19201 aacaacacca atgggaatat ctttagcaaa ttctttaaat ggtgtagaat caataacagt
    19261 tgtagccata atttttacag gtatttttgg tggtatggtt gcttctacag tattcaaact
    19321 ggggaatata aatcatccag ttgctaaagg aattgctctt ggaacatctg cacatgcttt
    19381 aggaactaca aaggcttttg aacttggaga aatagaagga gctatgagtg gtgtttctat
    19441 tggagtctct ggtacaatta cagtaatact aattccaatt ataatgaatt ttatataaaa
    19501 aataaaatta agacgagtaa cttgaatact taaaacaaaa taaaataaaa aaaatttaaa
    19561 ataaaaactg aacgaaaaaa atgcaaataa tgaaataaaa aaatcatgta ctgaaattat
    19621 aaaaagaaaa atttcattta ggaattaatt ataaagagac aattactaaa cttgaatttg
    19681 ctaaaataaa ataaattact gcgaaaatag atatttagaa aaaaatacta taaatttact
    19741 atattgcaag ttaaataata agcagtatca tattatgcta gaaaaagttt catttaaggc
    19801 ataaatgaga tgatttgaac gtttttaaag attagaatat aaaagattgc actagacata
    19861 tatgaaaaag ataatataat agatgatgta atagatgaca gttcaagaaa ttataaaaaa
    19921 aatttatttg aaatattatc tattacatca ggaataatat atgtaagagt aagcttttaa
    19981 aattctaaag atttagaaag attgaaggga gaaagaaatg agtgaagtta agaataccct
    20041 acaaaaacat ccagttttaa gatattcaac aatgctattt gggatgttga tgacatctat
    20101 aggaataaat gggttcttaa gaccagcaca tctacttagt ggaggtgcta caggtatagc
    20161 aacatctata aactatttga caaatataaa tgtaggttta ttaacatttt taatcaatat
    20221 tccaatattt atcttagggt tcatatacct tgaaaaagag ttttgtattt caagtttggt
    20281 aaatatgatt gtattttcat tattattagg agcaactcag gaaataagta atattatacc
    20341 tatacatgat atattgcttc aaagtgtata tggtggtata ttatctggtt taggagtcgg
    20401 agttgtattt agaactaggt cttctcaagg tggtacagat ataatagctg caatactaaa
    20461 aattaagaag aatatagaaa tgaaagacac tgctttagca ataaatggct tgatagtact
    20521 tacaggaagt tttttatttg ggttggattt agcattatac actcttatag gtctatttct
    20581 aaatgcgtat tcaatgagtt ttattaaaga tgcaatgaat taccaaaaat ctgttatggt
    20641 aatgtcaaat gaagtcgatt taatagcaga agatataatg aagagtttag ttagaggtgt
    20701 aactttttta gatgcagaag gtgcatacac tcatcaaaaa aagaagatta tatatacaat
    20761 agtttcatca aatgagatac caaagataaa agatatagct ttgaagtatg ataaaaaggc
    20821 ctttatatct gtaaatgatg ttacagaagt aaaaggaaga gggtttaaag caaaagattt
    20881 atagaaaatt ttacaagctg ggagtttata atgtaaattt gtatattata tctctcagct
    20941 tatttaaatt tagtatacga aaataaaggt tttattaatg atttgtgtat cactttaaaa
    21001 gatatcattt taaaattaaa attgaaaaaa ttacttaata tgtagaaaac atgaccacta
    21061 ttaggatata ataaatttaa tagatttagt aaaatatcta ggaataacgt tggaggaatg
    21121 gcattatgaa tttatctaaa gaatatgtta atttgtatga taattatttg aaatatataa
    21181 atgaagtaaa caaagagatt agaagtataa agaacatgaa gaaacgtgtt ttaaaaaggg
    21241 gcgattttgc tccagaaaat gaagtattag aattggaagg aaaaacaata cgcgatatag
    21301 atgatgtcga tacaaaaaaa ccaaaaaata aaatctataa attttcaaat ggggatgtat
    21361 atgtagggaa attcttagag ggaaagatgg aggggaaagg ctcatatact ttttttgtag
    21421 atgaaggaac agttatggag tacataggag aatttaaaga agataaaaaa aatggaaaag
    21481 gaaactttat attttcaaat ggaaatgaat atataggtta ttttgaggaa gatatgatga
    21541 gcggtattgg aaatatgtta tatagtagta aagatgaata tattggaact tggaaaaacg
    21601 gaaaaaaaga tggaaaaggt atttataagt ggagtgatgg atgtatatat gcaggtgaat
    21661 ttaaaggtgg aaagatggaa gggtacggta tttgctataa tagtaaaggg gaagtacttt
    21721 atgaaggaga atggaagaat aatttgattc atggtaaggg aacttatata tgggaaaaag
    21781 gtaaaaagta tataggtgaa tttatgcatg gtaaaaaaca tgggcaagga actttttatc
    21841 taaataatga attggtttat gaagggactt ggaaatttga taagccatct atatttgata
    21901 gaacattaga tgaaatattt tccttgagac tgtagcttta tctaattagt agataaagct
    21961 tttttctaat acttactgta aataggtatg aatgatattg attagtatac actatcaata
    22021 ttaacttaat aaatgcaata ttaaaaaatt ttgattgatt ttaagaagga gagatatatt
    22081 gaagagatta attgctttag tgttagtagt acttattgtt ttattttata gtcctgaatt
    22141 attaaaagaa ggatatgatt taaaagaaaa gttttttcaa agtgaaatat ggaatgaatt
    22201 tttagacaaa ataaatataa atgataattc taagaaagat aaaaaagaaa aaagtcaaaa
    22261 tttacaatca aataatactg aaggggagaa cttaggagag tcagatataa agaattttga
    22321 aaaaataagc ttaggagata atttaagcta tgttttatca agtatcggca aacctggtag
    22381 aattgatatt agtgaatatg gttttgattg gtatgtatat aatcaatatg gaaaagaatt
    22441 tgcaatggtt ggacttgaaa atgatgaagt agtagcactt tatagtaatt ctattaattc
    22501 atgtgaaaat caagatataa aactaaatca agatagacaa acagtgagaa ctaagattac
    22561 accattaaaa tataagagaa aaggaaatac cagatatata ataaactcag aaaatcaata
    22621 tgatataata agtaaggaag gtaagtatat tacaattttc tacgatattc atgaagaaaa
    22681 tagagtttgt tcatatttaa taattgataa aagcactgaa gatgagttta aaaatttata
    22741 tccagatgat agcgaagaac ttaaaaaatg ttttgaactt gaagttatag accttgtaaa
    22801 tagtgttaga aatcaaagag ggttaaactc attgagatac agtgaacagg caactttgag
    22861 ttcaagaaaa catagtgaag atatgagaga taataatttt tttgaccatg taaataagaa
    22921 gaatgaaact ccatttgaca gaatgaaaag agaaggtata gtatatactt cagctggaga
    22981 aaacatagca gcaggacaga ttaatgcaat atatgcgcat gaagcttgga tgaactctga
    23041 aggacataga aaaaatattt tggggaacta taataatatt ggagttggag taatatttgg
    23101 aggaagctat aaaacatatt acactcaaaa tttttataaa taactaaaat atttgaaagg
    23161 aagttaaaaa atgacatcat ggaaaaaaaa gacagtatat aagtgcttaa tagcagtagt
    23221 cttgttttgt ggaatagtgt taatatctaa ttttagtaaa gtttctgctt tgatgatgga
    23281 tactaatgga aatgttttga ttaaacatgg ttcaagggaa aaaaagctaa tagcaattac
    23341 ctttgatgat ggtcctcatc ctaaagaaac tagtcaagtt ttagatgtat taaagaaata
    23401 caatgtaaaa gctacttttt ttatagctgg aaaacatgca aaatggtata aagaaccatt
    23461 agtaagagca agtaaagaag gtcacgagat aggaaatcat actttcaatc atcctgatat
    23521 aagtaattta agttctagtc agatagaaga ggagattgtt aagtgtgaag acattttgaa
    23581 agaagtaact ggaaaaaaac cgacattatt tagaccacca tttggaagtt atagagaaaa
    23641 agaattaata gaaattgcaa aaaagcatga ctataaagtt gttttatgga caggtgtaga
    23701 tgtgaaagat tggaaaaatc caggagctaa tagcattgca gataaaataa ttaataaagt
    23761 acaaaatgga gatataatac ttttgcatga ttatgcaact aatgatacag ttgaagcttt
    23821 agatatgttt attccaaaaa tgattgaaaa aggttttaaa tttgtaacag tttctgagtt
    23881 aataaaataa tttttagggg ggagatttac agtatgattc ttatgataga caattatgat
    23941 tcttttgtat acaacctagt ccaatatata gaagaattag gggaaacagt tgtagtaaaa
    24001 agaaataatg aaatcaaaat aagtgacatt gaagaactaa atccagaggt aattgtgtta
    24061 tctccaggac cgtgttctcc aaaagaagct ggtatttgca tagatattgt tgagcatttt
    24121 aaggggaaaa aacctatact aggaatttgt ttaggtcacc aaactattgg acatgttttt
    24181 ggaggagata ttataaaagc acaacagcct gtgcatggaa aagtatatag tatcaaccat
    24241 actaataaag gagtttttag gggacttaaa aatcctttaa atgtcactag gtatcattca
    24301 ctaatagttg actccaatac agttccaaaa gaattagaaa ttacagcaat tactgataaa
    24361 ggggaaataa tggggattag gcataagaaa tatttaatag aaggagtaca gtttcatcca
    24421 gaagctattt tgtcagagta tggtcatgaa atgcttaaaa attttataac agaagctaga
    24481 gaaagggtac atatgtaata tgataagaga gataaatact aaattaaatt cttttgagat
    24541 atttactatt tttagaaatg aacatgacag ttttatatta gacagtgcta tggacaaaga
    24601 aaaattggga agatattctt ttataagtag ccaaccattt aaggtattaa agtataaaga
    24661 tactgatgaa aatcctttag aagttttaaa agaagaacta cataagtata gggttgtaaa
    24721 tgatactaat cttccatttg taggaggtgc tgtgggatat ttatcttatg atttaggtaa
    24781 ttacatagaa aatttaccta gaactgctgt agatgatatt gagatgcctg atatgtattt
    24841 tggattttat aatcatgtaa tagttataga ccatcttgtg caaaaaactt atatagctac
    24901 tccaaacata gatatcgaat tagaagaaaa gataatagat gatatagaac aaagaatatt
    24961 aaaagaagag aaaaaaggta tagatagcat atgttatgaa gaaaaagaag taacacctat
    25021 aagacttaaa tctaatttta caaaggaaga atttaaaaat gcagttcaaa gtgttagaga
    25081 gtacataaga caaggagata tatatcaagc taatttaaca caaaggttca gtggagaaac
    25141 agaacttaca agctttgaat tgtataggga cttaagaaga tttagcccag caccatttgg
    25201 ggcattctta aactttgaag atgcacatat attatcaaat tctccagaaa gatttataag
    25261 atgtgttaat aagagaatag aaactagacc aataaaaggt actcgtccaa gagggaaaga
    25321 taaagaagaa gatttaagac ttcaacaaga acttagaaat agtgaaaaag atagagctga
    25381 actacttatg atagtagatt tagaaagaaa tgatattggg agaatatcta aaactggaag
    25441 tgttaaagtt ccagagctat ttgtaattga accatatgca aatgtaaatc acttagtttc
    25501 cacagttgta ggtgagttaa aagatgataa agatgctact gatgtaataa aagcaacttt
    25561 tccagggggg tctataacag gagcacctaa gattagagca atggaaatta tagacgaatt
    25621 agagccaacg caaagaaatg tatatactgg ttcaataggt tatataggtt ttaatggtga
    25681 tatggatttt aatatagcaa ttagaacaat aatcaaaaat gacaaaaaag tctattttca
    25741 agttggagga ggaatgactt gggattctga cccagatgaa gaatatcaag aaacacttga
    25801 taaagctaaa tccataatga aggctttgag gggatattat gaagaataat gtaggttttg
    25861 atagtagttt aagtaaattt ggaattggtt tgtttgaaac tattagagtt aaaaatggaa
    25921 tagcagtaga tttagatatc catatagaaa gaatgctaag ttcaataaat tgtttggatt
    25981 tagatataaa atataaaaaa gatttcttga taaatgaaat tgttacatat ataaaaaaag
    26041 aaaatgtcat taataaagca cttagaatta ctgtttttga tgaaggttat aatatatcta
    26101 ttagggatat tccatataat caagagacgt atgagaaggg gtttaaatta gctatatctc
    26161 caatagttag ggggaatagt ttaattcata gacataagac tactaattat tttgaaaaca
    26221 tatataccaa aaatatcgca aataagactg gttataatga tggtatattt ttaaattcag
    26281 aaggtgtaat attagaatgt tctatgagca atattttctt tgtaaaagga gaaagagtgt
    26341 acactcctag tgatagatta ccgatattaa atggaataat aaaaaaaagg attatagaga
    26401 tttgtgacga attacatata gagttgatag aaaatgaaat taatatatca gaaattagta
    26461 gttttgattt tgtttttgtc acaaatagtc ttatgggcgc tataaaggtt acagaaattg
    26521 acaaaataaa atttaataaa gaaaatgttg tttttgataa aatagtgaag ttattagaat
    26581 aaattaaaat attaacaatt tgttggagac aaaagatgat aggttgtatt tatgaagtat
    26641 acaatgaaga gataactaaa ataatagaaa accaaaacac tttggctgta tatttagtgg
    26701 gttctagtaa agacgtagat tttactcttt atgatgtaga gataaacgat attgatgtgt
    26761 tcgtttttgt aaaagaaggg gaaaaacaag agagaatact gtttaaaaaa aagggaatag
    26821 aatttgatgt aaattacttt tcaaaagatg gtgtaaaaaa attattatca aatagggaat
    26881 atttctttgt gaaagaaatg aaagatgcta aagtactgtt tgatagggag aatatatcac
    26941 atattataaa agatataagt agaaatattt acttagaagg acccagtaaa atgtcattag
    27001 aggaaaagtc ttttataaag caagatattg gagcaaaaat atcgaattta aaaaataaag
    27061 aaaaatttga tgtttttgaa tatcattttt tgacgaattt atatttaaaa gatataataa
    27121 ttgggtactt taatataaat gataaatggg taccaaaaga caaaaaattg ctaaaagttt
    27181 taaaaaaaga aaataatgag ctttttgaac tagtgtcaaa agtaagtgaa aattatgact
    27241 atcaaagact tttagatgtt tataattata tttttaaaga aattgagaca aaagaggtta
    27301 taaaactaat cttctagtca caaatcaatg gggggagttt aaatgaataa agttgataaa
    27361 gaaaagatac aacatgcagt aagagaaata ctagaggcaa ttggggaaga cccagataga
    27421 gaaggtctaa tcgaaactcc aaatagagtt gctaggatgt atgaagagat attctctggt
    27481 cttagtgaag aaccaagaga ccatttaaaa gttctttttg cagatgaaaa acatgaagag
    27541 ttagtattgg taaaagatat tccattttat tcatgttgtg agcatcatct agttcctttc
    27601 tttggaaaag ctcatattgc ttatttacca aaaggaggaa gacttacagg gctttctaaa
    27661 cttgctagag taatagatac attggcaaaa agaccacaat tacaagaaag aatcactaaa
    27721 aatgctgcag atataataat ggaagaatta caaccttatg gtgtcttagt agtagtagaa
    27781 gctgaacata tgtgcatgac aatgagaggc gtaaaaaaac caggttcaaa aactgttaca
    27841 tcagcagtga gaggaatatt tgaaaaggac attgcgtcta gagccgaggc tatgagtttg
    27901 attactatga agtagcaatt tattatagat ataatcattt attgagataa aatttaattt
    27961 aagggagtgt cattaattgt gtttgattat ggtaaaagaa cttatataat gggaatatta
    28021 aatgtaactc cagatagttt ttctgatgga ggagatttta ataacttgga catagcaata
    28081 caacatgcaa aagatatggt tgaccaaggt gcagatataa tagacctagg aggagagtct
    28141 acacgcccag gtcatagcta tgtagactca gacgaagagc taagaagagt aatccctgta
    28201 ataaaaaaac ttaaacagga attggatata ccaatatcaa tagacactta taaggcagat
    28261 gttgcagaag aagcattaaa attaggtgtc actatggtaa atgatgtttg gggtcttaga
    28321 aaagataaaa atatggcttc tgtaatagga aaatatgatg cagaagtgtg tataatgcat
    28381 aatcaagatg ggacaaacta tgacaaagat ataatggagt caataaaaga cttttttaag
    28441 gtaagtatag aaatggcaat gagttgtggt gtaaaaaaag aaaaaatagt acttgaccca
    28501 ggtgtaggat ttggcaagga ttttgaacaa aatattgaag tattgagaag attaaatgaa
    28561 ttaaaagatt tagggtatcc tattttgctt gggacatcca gaaaatcagt aataggaaaa
    28621 gtacttccag ttgagcctaa aaaaagatta gaaggtacaa tagctactac tgttcttggt
    28681 ataagagatg gcgtagatat agttagagta catgatgttt atgaaaattt aatggcagct
    28741 agaatgactg atgcaatata tagaaagtag gtataatata atggataaaa tattacttag
    28801 taatctagga ttctatggat atcatggtgt tcttaaagaa gaaaattttc taggtcagaa
    28861 attctttgtc gacatggaac tttatattga ttcaagagaa gcaggtctta gtgacgatat
    28921 aaataaatct gtaagctatg ccgaggttta caatgttgtt aaagatatta ctgaaaataa
    28981 acaatttaat cttttggagg ctttagcgga aaatattgct gaagaagtct tgaataaatt
    29041 tatacttata aatggagtta tggtcagagt tagaaagcct gaggctcctg taaatggtat
    29101 ttatgactat tttggtgttg agataaggag aacaagagat gaataaggct tatttgggaa
    29161 taggtactaa catgggtgat agatttgata atttatcaag agcatgtgaa cttttgaaaa
    29221 atagtgattc tatatataaa gtaaaagaat caagcttata cgaaacaaaa ccatggggat
    29281 atacagaaca agcagatttt ctaaatatgt gtgtagaaat agaaacagag tttgaacctt
    29341 atgagttgtt agaatattgt caagaaatag agagagaact acacagagag agaatagttc
    29401 attggggacc aagaactata gatgtagacg tactattttt taatgatgta gtttccactg
    29461 atgaaagact aacaatacct catccaagga ttcaagatag agctttcgtt ttgataccac
    29521 ttatggattt aaatgaagaa cttataataa atgaaaaaac aataaaagaa catttaaacc
    29581 tcctatctgc tgaagaaaga gaagaagtaa aggagcttgt aggttatgaa agaaaaccta
    29641 tttaataata attcaaagat agagataaat acaaataaca aaaagataac tgtaaaaaaa
    29701 gataaactta taatagctgg accatgcgca atagagagtt atgagcaact tttggagact
    29761 gctaaatttg taaaaagtca aggagcaaac attttaagag gtggagcata caagccaaga
    29821 acatcgccaa attcatttca aggattaaaa aaagaaggtc ttgaaatatt aaaagcagtt
    29881 aaagacgaag ttggtatggc tgttattaca gaacttatgg atgtaagaga tatggacgaa
    29941 ctgtatagta taagtgatat aattcaaatt gggtcaagaa atatgcaaaa ctttactctt
    30001 ttaagtgaag tgggaaaaca aaataaacct gttatgttaa aaagaggaat agcatccaca
    30061 attactgaat ggataggtgc ttctgaatat atagcaatag aaggaaatag taatattata
    30121 atgtgtgaga gaggtataag aacgtataat gattatacta gaaatacatt agatttagct
    30181 gcggtaccca ttattcaaaa ggaaacaggt cttcctgttg tggtagaccc aagccatgcc
    30241 actggagtta gatatttggt aaaacctatg tcactggcat cttttgcatg tggagcagat
    30301 ggaataatgg tagaagtaca tcctgaccca gaaaatgctt tgtcagatgg tgctcaatct
    30361 ctttgcttta atgaatttga agatttaatg aaatcaatta ataattatta aaagaggcaa
    30421 gagcctcttt tttattcgta atcgttgcta aggtaaattt ataagttata atttgatagt
    30481 tagattattt aatataaata aagatttaat attgatagaa ttaatataaa aaataaaaat
    30541 tttttgatta ataagaagga tatcaataaa aaaagtcgaa ttgtgtatat tgagtgattg
    30601 acaaatttag aatatagtgt agaatagaaa tgttaacaca aaaaattaca ccagaaggtg
    30661 ataatatgaa tgatataaaa gacattattg aagaaataaa agctagatgc gatatagcaa
    30721 gtataatatc tgaatatatg aatataaaac aatctggagc taattacaaa ggattatgtc
    30781 catttcatgg cgaaaagaca ccttcttttt atataaatac atcaaaacag atttataagt
    30841 gttttggttg tggtgaaggt ggagacgtaa taaattttgt catgaaaatg gaaaatttgg
    30901 attttatgga tgctgtaaaa attttagcaa ataaatgcgg tatagaaatt aacactaaca
    30961 tgaatgaaga aactaggatt aaaatagaaa aatctaagaa atttcaagat attcatacgg
    31021 aagcagctag attttatctt tcaaacttat tgggaagcaa aaatcttggg tatgaatatt
    31081 taagaataag aggactagat gataaaatta ttaagaaatt tggtttagga ttttctttgg
    31141 attcatggaa ttcacttatg aatactctaa tcagtaaagg atataaaaaa caagacttat
    31201 tagagtgcgg tctaattgca aaaaatagag atggaactaa ttgctatgat aaatttagaa
    31261 atagagttat gtttcctata ttcgattata gaggaaatat aataggattt gggggaagag
    31321 tattagacga ttctttgcca aaatacttaa attctccaga cacattaatt tttaataaaa
    31381 aacagaactt atacggatta aattttgcta gaaaaaattt agaaagtaaa actatagtct
    31441 tagttgaagg atatatggat ttaatttcac tttatcagta tggtataaaa aatgtagtag
    31501 caacccttgg aacagccttg actgaacaac aaggcatttt aataaagaga tatgcggaca
    31561 ctgctattat atcttatgat tctgatgaag caggaataaa agcgacttta agagctatag
    31621 atatacttac taaattaggt atcaatgtaa aagtgttaga cttaaaagat gctaaagacc
    31681 cagatgaatt tgtaagaaaa tacggactta gtgattataa aaaagctatg gatgtttcta
    31741 ctcactacat aaaatataaa atagatcatc ttaaaaaaga atttaacatt caaaaagatg
    31801 aagaacgagt gaagttcgca aaagaagctt ctaaaattat aaaacaattg acaagtcctg
    31861 ttgaaattga tttttataca aagtatttaa gcaatcaaat agatattaat gtcgagtcta
    31921 taaagagaga agtttatggt aaaaattaca ataagccata taataacaaa aatcaaaaga
    31981 aaatagaaga aaaagtaatt gaaaaagtcg aagtcagaca agacggaaaa caattagttg
    32041 aagaaactct aataaaaata atgttagaag acaaaaaaat tagagaaata gcgttactta
    32101 aagtagaaga aagtgatttt ttattgaaag aaagtaaaga aattttaaat tacatgatta
    32161 aaaatcaaga attggacaaa ataactattg acaaattgaa aagtttaaac atatccgaag
    32221 aatacttaaa agaattaaat tcaatttctt tgaatagtat aaacttagag aacacaaaag
    32281 aaatagaagg aataataaca aatatcagaa aaaactcatt agaagagcaa attaatagct
    32341 tgttgagaga acaacaagaa ttagaaaata ataatgatat gaaagaggta gatggtagag
    32401 ttatggaaat tgctttaaaa atagttgaga taaataaaat tttaaagagc ttgtagagaa
    32461 aggaggtttg agtgtggaaa ataaatcgaa taaaaaagag ttaaaaaagg ttactgctaa
    32521 gacattaata gaaaaaggaa aaaagcaagg ttctctgaca cttgcagaga taatggaagc
    32581 tttttcggag actgaacttg ataaggatca agtagaaaat ctttatgaga ctttaggaaa
    32641 tttgggaata gaaataacag aaacaaaaaa ctataaagct gatatagatt tttcggttgc
    32701 tgatgacgat ttaagtatag gccacttaga tgaagatgca gaggcaattt cacatgatga
    32761 ctcttctgca atagaaatag aaactgtgga tttatcttta ccaaaaggga taagtataga
    32821 tgaccctgta agaatgtact taaaagaaat aggaaaaatt cctctactta aaccacatga
    32881 agaagtagaa tttgctagaa ggatgcacga aggtgatgag atagcaaaac aaaggttagt
    32941 tgaagcaaac ttaagactag ttgtaagtat agcaaaaaga tatgtaggaa gaggtatgct
    33001 tttcttggat ttaatacaag agggaaattt aggtcttata aaagcagtcg aaaaatttga
    33061 ctatacaaaa ggatataagt ttagtactta tgcaacatgg tggataagac aagctataac
    33121 acgtgctatt gcagaccaag ctagaactat aagaatacca gttcatatgg tagagactat
    33181 aaataagcta ataagagtat caagacaact acttcaagaa cttggaagag atccaaaacc
    33241 agaagaaatt gcaaaagaaa tggaaatgac agaagataaa gtaagagaaa taatgaaaat
    33301 agctcaagac cctgtgtctt tagaaacacc aataggagaa gaagaagata gccatttagg
    33361 tgactttatt ccagatgatg atgctccagc cccagcagag gcagcagcat attctttatt
    33421 aaaagaacaa atagaagatg tacttggttc attaaatgat agagaacaaa aagtattaaa
    33481 gcttagattt ggtcttgagg atggtagagc cagaactctt gaggaagttg gaaaagagtt
    33541 tgatgtaact agagagagaa taagacagat agaagcaaaa gcactaagaa aactaagaca
    33601 tccaagtaga tcaaaaaaac ttagagatta tttagactaa aaagatacat cattgatgtt
    33661 tttgtgataa atgccatgag ataagtgata tctcatggct attttgtagt aaagatttaa
    33721 ttttattttt gtagttattt cagtctaata tctataactt ggattaaatc ctataaataa
    33781 agggaattga aaggagaatt atatttgaaa ttaacagata gattattgaa aatagcatca
    33841 ttagtgtcag atggtaaaaa aatagctgat ataggaacgg accacggata cataccagta
    33901 tatttgttaa aagagggaaa agtaccattt gcagtgctag cggatgttaa taaaggacct
    33961 cttgacaatg cacataaaga agtcatacag aacaatcttt tagataaagt tgatttacga
    34021 ttgggttctg gtatagagat acttgaaata ggggaagtag aagaagtgat aattgctggt
    34081 atgggtggaa tcttgataag tgagcttctc gaagctaaaa aagaagtagc acataatgta
    34141 gaaaaattaa tattacagcc aatgcaagca caagaagaac ttagatatta ccttttaaac
    34201 aacggatatg aaattttaga agaagtttta gtgagagaag attttagaat atatgagata
    34261 attgttgcca aatatacagg taaaaatact ataatagaag atgagatata ttatgaggtt
    34321 ggaataaagc ttttagaaaa caaagattct ctttttaatg attttataga aaaaaagata
    34381 aagacatata gttctatagt taataaatta gaagggaaaa atggggaagc tatagataag
    34441 aagagaaagg aaagcgaagt tgcaataaaa aaacttgaaa atttaataaa ataaatagga
    34501 ggtatatatg ctattaaaga gtctaactag aaaaattgaa aaaaagtatc ctctaaactt
    34561 agcagaggat tgggataatg taggtcttat agttggagat tttgatatgg atgtaaaaaa
    34621 ggtattggta tctttagaag ctaatgaaga tgttattgat gaagctatat ccaaaaatat
    34681 agatttaatt gtgacacatc atccttttat atttgggaaa attaataaaa ttaatagtgg
    34741 agatttaaaa ggcagactta tccaaaaact tattaaaaat gatatatcac tttattctat
    34801 gcatacgaat tttgatatag catttgatgg tctaaatgac tattttatgg aaattatgga
    34861 atttggtaat tcaaaggttt tagatataac taaaagcgaa aatttgtata aattagcagt
    34921 atacgttcca cataactatt cagatgaact tagaaaggtt ttaagtaatt caggagcagg
    34981 tcatataggg aattatagtg attgtacgtt ttcaacagaa ggtgaaggac aatttaagcc
    35041 attagaaggc tctaatccgt ttcttggaag tgtaaatgat atagaaactg taaatgaagt
    35101 taaaattgaa actgtagtac cacagaagct tttaggtggg gtaataagtt ctatgttaga
    35161 tgcacatcct tatgaagaag ttgcatatga tttgtacaag ttagaaaata aaggtgagat
    35221 atttggacta ggtagaataa gtaaacttga taaaagtatg acattagaaa gtctttcaag
    35281 gaaaataaaa gagaaattaa atatgaaaca cataagagta gttggaaacc ttagtacaga
    35341 cataacgaaa gtagccgttg taacaggagc tggttcagaa tttgtaaaaa aagctaagag
    35401 acaaggtgca gaagtactaa ttacgggtga tgtaaagtat catgaggcac aagatgcact
    35461 tgatattgga atgtgtatag tggattgtgg tcattttgat acagaagata tattcaaaaa
    35521 tgttatgaag agatttttag atgaatttag tgaaattgaa gtaataaaga gtaatgtata
    35581 tttgaatcca tttagtacta tttagcagtg tttgataata aaaatactat ataaaaaata
    35641 aatttgagtt taattagggg gataatgatg aaagtagcag taatttttca tagtgtttgt
    35701 gggagtacat atttattagc tagagaatat aaagaagcgc ttgaagaaat gaatatcgag
    35761 gtagatatat ttagagtaag tgacgaagtt gcaaaaacac ttcctcaata ttatttgata
    35821 aattccaaag aatacaaaga cgaatttgaa agtataaatg taattaaatc tggaaaagaa
    35881 atattagatt atgatgctat atttatgggt tcaccaacat attatggaaa tgtatctgga
    35941 ccaatgaaga tgtttatgga tagtttttct gatatttggg taggtgctcc tttgagtggt
    36001 aaaatatttg gttgttttgc tacagcaggt tcacaacatg gaggaggaga attagctttg
    36061 caagctatga atatatttgc ccaacatatg ggaatgactc ttttgtcagt tccatgttca
    36121 gtaagaggag gttatccagc gtatggaata cttcatatag caggagataa ttctgatata
    36181 aggccaaatg atgatgccaa gataggtata agagattacc taaaaagact taacatataa
    36241 gaatatcata taaaaatacc taaaagcgac tgtatatact tttaggtatt tttacttaat
    36301 tataaacgtg aagctttacc agaaatatgg tcaatttcta ttttaacaac agttgttaag
    36361 ttcatatcct tctctatgta cttcatgcct tcttcaaaga atcctttaga atattttttt
    36421 attatttcta caagagcatt tttcttttct tcattttcta cagtgcaagc ttttccaaaa
    36481 actatagcac tagaataagt agtactaaat ttatctggaa taacactttc attagcaact
    36541 actaaaaaag aaactttgtt gtttttcgat atattatcta acttatgccc atttcttgca
    36601 caatgaaagt aaatagaatc attaaagtat acataattta cagcaactcc ataaggataa
    36661 ccattttcag atatagtgga aaaagtacca aattcaccat tttttaatac ttcaacagta
    36721 tcttcttttg tcatttctct ttttttcaat ctcatttctt taaacataat atcatccttt
    36781 ctaattttga tgcttaaatt aaattttaga acatttataa agattatgct atgtttttta
    36841 caaattttaa gaaaaaaata tagtttaaga taaaaggtag tgaaagagaa gctatttgga
    36901 ggtttattta tgatattatt gttagagtag tacaaataat actaataaat ttaatagctg
    36961 gtttcttgtt atttaaggta gtaagcatgt ctataagaag gggaagttat cgagggtaga
    37021 agttgttgtt tataacgata ttataaagaa aatattatta tataaaataa taaatagtaa
    37081 agaggtatca agttgaatat aatacttaat acctcttcaa aattaagtta taaaagtgtt
    37141 gtgggaattg tcctatacat ggtaaggaga taataaagaa tgtatcttta aagtctcaac
    37201 taaacagcaa aatttatcca acaaacatac aataaatgct tctttgtatc taggtggctt
    37261 aacagtaagt ggccacatgt gttttaaaat tatgtccgtt tctttttcat ttatttgaaa
    37321 aaataaagtt gcatttttta atgcttctct agggtgagta aatccatgta atccttttct
    37381 atcacctttg taatgccaat cataaagaaa aaagtcgtgt agtaaagctc ctctaataac
    37441 actttgaata tcaacactta agtgcaattt tttacataat agataactat aatatgctac
    37501 tgacaaacta tgttcaagac atgaaacatt gccatgatga ggaaatgttc tcataagttg
    37561 aactttttca gaagaaagta tctcagaagc acattcatta aaatatttga tttcagcttt
    37621 tgacaacatt atgaaaatct ccattcttag taatatataa atactatact tcaacgataa
    37681 tatgaaatat ttcttatcct acaaaatata atacccaata atacaagtaa gatacctttt
    37741 atggtatttt aaagtaagag agattttatt aggctaaaca atgaaaaaat taaaagtaaa
    37801 gctatagcaa tatatagtat ttttccaaga ggattgccaa aatttatagt ccatccaata
    37861 ccaaaccttt tattaaccat taatgatggg tcatttggat tattatacat gatgcctgct
    37921 atccaatact tctcatcttc ttctggagaa taagatgagt tgaattttaa atttggggaa
    37981 ttaatatatg ttgctattaa ataaattata actaaaagcg ttgtaatatt catagcagtt
    38041 aatagttttg tttttattga taaaagagta gtaaaaaact gtgttgtcat tataatcatc
    38101 aatattaaaa acaaataacc aattttattt aaatatttaa tgttttcaac tctactttct
    38161 tcaattctat ttgtatctat cttaatcctt gactttatgg atccaatgga agttatatat
    38221 aataaaacca ttaaacaaaa gtcagtaccg attaatttaa atacattaag aaatgattta
    38281 tctataaaaa catcaggaga cccatttatg ttccaatgag tggcaattga gtctggcaat
    38341 tgattataat taaatgctat aaaaatactc attcccaaag taaatagtat cggtattaaa
    38401 tagattattt taaatttttt tattatttta tttttcttat ttataaaatc catatctact
    38461 attaattttg aatctatatc tatatgacct aatttagcat aaatttctga tttaagcttc
    38521 ttagcttttt tatgtgtatg aatatatagt atactttcat ataataaaaa acctataata
    38581 ccaataaaat aggaaagttc caatttatta aatgtaaaga ccagaataaa aactaatata
    38641 aagtctataa taaaacctaa agataatagt tttttaaatt ctttatctaa ctttataaag
    38701 taattataat ttttatgctc ttggtctata gaaactccat agatgtgttt tttacctaca
    38761 aaatagggta taaaataaaa tgtagcatac atcaaaatta gaactggaaa tattgtaaat
    38821 agacattcaa tcttactcat aatatttcac ctcatacttg tcaaataaac ttgaacttag
    38881 tgacaaaaat tcttctttac taatacctga taaataagat tttgccacca ataattccaa
    38941 gtcaagttta tttttttgac gagttgtatt atctattttc attggtagtt gagctacaat
    39001 agcacctttt cttctatcaa tatttaagaa tccctcttct tttaattcat tgtaggattt
    39061 gttcactgta tgtaaattta caccaatatt ttcagccata cttcttacag atggaagtga
    39121 ttcatttatt ttcaattctc ctgaagctat agccttagtt atttcttctt taatttgtac
    39181 ataaatagat ttatcactat taaaatctaa atttaaaacc ataaaaaacc tccattatgc
    39241 tttataaatg aaaacgattg ttatatacat agtataacat aaaaaataat aacaaacaca
    39301 aaatataagt ttatattttg taaaaattgt aatttaaaaa ataacataat ttttattaaa
    39361 ataatacaga tactatttat agatagaaat aaaaattaga aaggagaaaa aatatgttaa
    39421 catatttaat gaaaagacaa atgcataaaa aagatgatgg aatgagtaaa ccaatgatga
    39481 ttacaggagc tgtaattaca ggtgtaggag catatgctgt atataaaatg gtaaaaagcc
    39541 ataaatctaa ttctcaaatg gtcaatacaa attattatgg aaatagcgat tatgatgatt
    39601 ataaatatga cgaatttgat tatgactgtg attgtagaga cacaaaacaa gattatgaat
    39661 atgaagaatt aaaaaaaaaa gtaaaagaat ttaattcaag aagaataaat tgtgaaaatt
    39721 gtccacatgt ttctcaagaa gaaatgatgc aatatgtaaa tagtgttaaa gatgtaaagg
    39781 aagagcttga tttacatgaa gatgctaaaa aagataatat ttacaaagaa gatgaataca
    39841 aaaaatatga agaagaataa gtaatatttt gtataactga acaaatagta atgtcaaatt
    39901 atttaatatc tagttttaat atgtaagttg taacttaact tgaaagaatc agtatcattc
    39961 tttagatagt taagtaacaa cttacatttt atttttataa attttaatag ttctttgtga
    40021 ctattttgta attttagaaa tattttagta tccagggtaa ttgtgtataa taaaacttgt
    40081 atagatagat agtatgaaat taagcagata gtttaaaatt aaaatgaaaa gaaaggaaat
    40141 agttatgtta aagttgttga tagttgaaga tgatagtact atatcttttg gaataaagta
    40201 tgctttagaa caagaaggat ttagtataga tatatcaaag gatttatcta gtggaaaaga
    40261 aatgatttct tctaatgaat atagcatgat actgttggat gttacattgc cagatggaac
    40321 tggttatgag ctttgtcaat atataagagg attctctcag gttcctataa tattcttgac
    40381 tgcttgtgat gaagaagtaa atattgtaat gggtctcgat ataggtggag atgattatat
    40441 aacaaaacct tttagaatta gagaattaat atccagaata aaagctgttt taagaagaaa
    40501 aggtaatact tcagaagaaa ataagaaaat acttaaattt ggagatttaa gtatatatac
    40561 attagaagct agagtatata aaaatgataa agaaatattt ctgacatcag ttgaatataa
    40621 acttctttta attcttatac agaataaaaa tactgtttta agtagaactc aaatattgga
    40681 aaaactttgg gatgtaactt atgattttgt aaacgacaat actctaactg tttatataaa
    40741 aaggcttaga gaaaaaatag gtgatgattt atgtgaacca atctacatag aaactgtaag
    40801 ggggattggt tataaatgga taggaagtga aaatagtgtt tctatataat ccagaagtga
    40861 agaagttttt aagtaagtat gttactttga tgtttattgt tatcataata tctattggat
    40921 ttagcataat caacgtgtcc ttaactaaag agatggttgt aagaaataat caggctataa
    40981 taggaacttt atcaagcaag tatccaaact tagaaagtca gatagtagac ataataactc
    41041 aagggaagtc tatggagaac atagattatg gtcagaaaat attaattaag tataattatg
    41101 ataaatctat taggataaac tctgagccta ttatttctaa attagtttta gagactatca
    41161 aaataaatat aatattagta tgtataatat ttattttgat atttgtgttg attgttagat
    41221 attttacgtc aatttacaat gatttatcag atatgactaa gtatgtttac tatagttcag
    41281 agggtaagcc atttgatatg aaaaacaaga atcaagaagg gcagataggt cttctaaaaa
    41341 ctgaactctt aaaaatgacg acaattctta atgaaaaggt tgaactttta aaaagagaaa
    41401 agatattttt aaacaataca atttccgata tatcacatca attaaaaact cctatgactt
    41461 ctttaataat gttgaatgat ttattatata atgatgtacc atacgaagta aaaatcgatt
    41521 ttttaaataa gataaaaaat caattaaata gaatggattg gttgattaaa agcatgctta
    41581 aattatcaaa ggtagaagca aaagtgataa attttaaaaa agataaggta aaatttagtg
    41641 aactcataca tagagcaatg ctatctatga aaatacctat ggagattaaa aatcaaaaac
    41701 tgactataga gggaaatgat aatgtatctt atattggtga tattgattgg tccgtggaag
    41761 cattagtgaa tataatcaaa aattgtgtag aacatactcc tgaatttgga aatataatta
    41821 taacctataa agaaaatcca ttattttctg aactaataat aaaagatgag ggtgaaggta
    41881 tagataaaaa agatatacca catgtattta aacgattcta tagaggaaga agtagttcaa
    41941 aagaagatag tgtaggaata ggtcttgcaa tgtcaaaatc tataatagaa agccaaaatg
    42001 gcgatatata tgtaaacagc gaaaaaggta agggtacaga atttcatata atatttcata
    42061 aaatgtatga tagtgactaa tctgtaatat ttaattcact ttatagtaat agccaaaacc
    42121 taatatatga agtatagaat ataaatattg gaggtagtta tggaaatttt aagagtagaa
    42181 aatctaacta aaagttatgg taaaaatgaa acaaaagttg atgctataaa aaatgtaagt
    42241 ttatcagttg aaaaaggaac gtttatagca ataacaggtc caagtggaag tggtaaaagt
    42301 accttattac atttattagg aggagttgac agaccaacta gtggtaaggt ttatataaat
    42361 gatgttgata tatataattt aaaaactaag gatttggcga tatttagaag aagaaatata
    42421 ggtcttatat atcaatttta caacttaatt ccagtcttaa atgtgaagga aaacatattg
    42481 cttccagcag agcttgacaa tagagatatt gatagagaat attttgatga tttaatgaaa
    42541 acattaggtc taattgatag agaaaagcac cttccaaacc aagtatcagg aggtcaacaa
    42601 cagagaacct ctataggacg tgcattaatt aatagacctt ctataatatt agcagatgag
    42661 ccaacaggta atttagatag taaaaattca aaggaaatat tagaattgtt aaaattgtca
    42721 gtaaaaaaat acaaccagac actaataatg ataactcatg acaaaaatat ggcacttcaa
    42781 gctgatagaa ttataagcat agaagatgga atcataaaaa gtgatgaggt gatgtagatg
    42841 aatttatata catcactaac tattagatac ttaaaacaaa ataaaagaag aaccattgta
    42901 accataatcg gtataatact ttcaacagct ttaatttgtg gtataggaaa tatatttgaa
    42961 agttttatgg attatcaaat gagagaaact ataaagaatg atggaagttt ccatgttaca
    43021 ttttatgatg taaatagaaa aaatgtggaa tatgtaacga aatcagctga aatagaaaaa
    43081 catgcattta ccaaacaact tggatattct aaattagaaa atagtgaaaa tgctatatta
    43141 agtataaagc aatatgataa aaatgcaata aatggatata aagtttctat aaaagaaggt
    43201 agatttccag ctaaggaagg agaaattgtt ttaagtgaaa gtattattaa tcttatagat
    43261 gataagttaa aaataggaga taagataact ttaaaagtag gggatatgtt tgactcaagc
    43321 aagaaaaaga ttgatagtat gacatttcat gaaggtgatt atatagcaaa tgaaaaagat
    43381 agaactttta aagttgttgg tataattgaa aaacctgggt ttgaacgtta taatggaatt
    43441 gcaacagcta tagcctactt taatcctatg aataattaca atgatacaat taatgtatca
    43501 gtagcagtaa aaaatcctaa agatgtgtat aagataagta ataaaataag taaaaatata
    43561 tattcaaata aagataaaga agcagtttct gatatgataa aatacaatga acatttattg
    43621 aggttacaag gtgctagtaa gtattcaaat ataaatagct ctataaagtc tataattata
    43681 gcagtaacta ttttagtaat cgtatgtaca attgctacag tgtacaattc ctttagtatt
    43741 tctataaatg aacgaaaaaa acagtttggg atattaaatt ctataggtgc tacatctagt
    43801 caaattaaaa gattagtttt tatagaaggt attataatta gtttaattgg tataccaata
    43861 ggactaatat ctggaacagt agctatagac ttattgttta aaattataaa taagtatttt
    43921 actgaatcgg ttgttactaa gatgagtttg cagatagtgt ataatccaat aataattatt
    43981 gttagtataa taatagtttt gcttacaatc tttatatcaa ttctactacc tgcaatatcg
    44041 gcttctaata tttctcccct taatgtgatt aaaaatactg gagagtataa agtgggcaaa
    44101 atcaaaagct caagacttat taaaatgatt tttaaaactg aaggagtact tgcatataaa
    44161 aatattagga gaaatagaaa aaaatttata ataactcttt tttctttaat ggtaagtata
    44221 ataatattta tatcttttag tggctttaca ttacttttac taagaggtga agaaattaga
    44281 aattctcaaa gaaaatatga tttgtattta actgcaaaga acacagctag gtctgtagag
    44341 gatactataa gtgaactaga agatattgat gggataaaaa actttgaatt ggcaacagga
    44401 caatatgtgt ctataagagt aagtgaaaat aaaataaata aatccaagga agatttaatc
    44461 aggaaatatt atcaaaaata taagattgga gatagttatg aatatgattt cagtaataat
    44521 gaattaattt ttccaggaga ttttgcagta aaaaacaaaa taaataactt agtacagggc
    44581 tcttttaata aagagagagc aattgaagaa aatggtgtta tattagttag aaaaagtgca
    44641 attgaagaaa atgggaagaa aggtgtagta gaacttacca actataaagt aggagataca
    44701 gtaaattgtg aatatcttga tgaaaatgcc ttaagtaaaa aagtaaaggt caagattctt
    44761 gctataactg acgaagaacg tctaggtctt ggttatcaaa atatggggtt acaatttata
    44821 acttatgatg aagttgctaa aaatttaaat ttaaaattaa gtaaaagcct tatatttatt
    44881 gattcaggag gaagcattaa gactaagaag gaaatagaag ctttggcaaa taaaaataat
    44941 tttaactttt atgatgaaag tgcaagcaat gaaagtgaaa aacaagattt aaaggttatt
    45001 aaaatatttg tatatggttt tatagtagtg atatctttag tgagtgttac aaatattcta
    45061 aatacagtaa gtacaagtat aaatctaaga aaaagagaac ttgcagtaat acaatctata
    45121 ggggttactc ctaaaggatt taggaaaatg atatatttag aaagttttat atatggtata
    45181 ctgtcattgt tgtttggaat accaattagt attggtataa ttctaattat gaataaactt
    45241 atttcaggtg taattgaatt ttctccgatt ataccgtgga cagccatagt tatctgtata
    45301 gtaagtgttt ttataataac ttttatagca gggtatatac caatgagtaa attaaataaa
    45361 gaaaatataa tagataatat aagaagagaa agtatataga tataaaaata attcttaact
    45421 atataaaata ttattaaaat catttaagtg gtataaaata ttattatatc acttaaataa
    45481 ttttttattt atataagaaa tctaataata aattactaga ggtatttaac tatttagaaa
    45541 gaattggtat tatataaagt aagagaatat ataataagaa agaatatttg attttattgg
    45601 aaaacaaaag aaaaagaagg tgattactat ttctcatata actgcgaaga atatgtataa
    45661 aagtttagag gaaagaataa acaagtttcc acaaggtgct ccaccatctg atacattata
    45721 caaaatacta aatgtactat atacagaaca agaggcgaag ttagttgctc agcttccaat
    45781 aaagcctttc agagtaaaaa cagcagctaa aatttggagt gtaagtgaaa gtgaagcata
    45841 tagagtattg gataaacttg ctagtaaggc tctgatacta gatatagaag ataataaagg
    45901 gaagaaatat ataatgcctc ctccaatggc tggttttttt gagtttgcca tgatgagaac
    45961 gagacacgat atagaccaaa aacttttggc agagctttac tatcaatata tgaatgtaga
    46021 agaagatttt atcaaagatt tattttattc aacagaaacg aagcttggaa gagtatacgt
    46081 tcaagaggaa gttttaacta atgataatga ggttagtatt ttagattatg aaagggctac
    46141 tcatataatt gatgaatcaa ctcatatagg tataagtatg tgttactgta gacatagaat
    46201 gcaacatgtt ggaaaagctt gtgatgctcc tatggatata tgtatgacgt ttgacaatgt
    46261 agcaaattct ttaataaata ataaatttgc aagacgtgtg gataaaatag aatgtaaaga
    46321 gctacttcat caagcatatg aacataactt agttcaatgt ggagaaaatg ttaggaaagg
    46381 ggttacgttt atatgtaatt gctgtggatg ttgctgtgaa gcaatggtag cagctaaaag
    46441 atttggaaat cttcatccag tacagacaac aagttttata ccaaatataa accatgaaaa
    46501 ttgtgtaaag tgtggtaaat gtataactgc atgtccaata gatgcgataa gcaaggttaa
    46561 ggaagatggt aaagaatata taaaaattga tgaggataga tgtttaggtt gtggagtttg
    46621 tgttagaaat tgccataaaa atagcattat gttattaaag agagatgaaa aaataataac
    46681 tccagcaaat tcagtacata gagcagttct tatggcaatt gaaaaagggc agttacaaaa
    46741 tttaattttt gataataatg ctctggctag tcatagagct atgggagcta tactgtcagc
    46801 tatattaaag cttgaaccag ctaaaaagat tttagccagt aaacaattaa agtcagtata
    46861 tttagataaa ttgttaagta tgaatgataa atagaaacta acttaaaaaa ggcaaagttt
    46921 tagacttatc tatatcttaa taaacttatc atttaatatt taaatttaat ttttacacat
    46981 ataaaactta taacttaaat aaaaaaaggc tatattcaat taatattact tgaatacagc
    47041 cttttttagt tatgttaagc tatttctttt atttgcttaa atgagttttc atttccattt
    47101 ccaccaattt gtgttacaga tttaaatctc atagttttaa atagttcttt ttgattataa
    47161 tctagtgagt ttcctactag cattacagga gatttagttt ttccagccaa aactccaaca
    47221 gataatccgt ctattaaatc atcttgttta ttcattccat ttttagcaac atataaattg
    47281 tctatcttag aatccttgta aaattctttt attacttttg cattagtttc atttctagtg
    47341 ctacctgata ttctctgtgg attttgaagt ttactttcta tatttttaga aactgtatat
    47401 tctccaccga ttacataaga tttatcaatc tttttgtttt taaacaagtt atttatttca
    47461 gttatattac tattttcatt agtaagtatt ataggcatat cattttgagc tgatacagct
    47521 ccaatgctta ctgcatcggc taatcctttt tcgccattaa ctactgaaat ctttgatata
    47581 ttgctaatat tgttcaattc tttagcaatg ttcatagaag tttgatatct atcacttcct
    47641 gaaattctag atacagagat attgtttgat tttatagtat ctaaagattt ttcatttata
    47701 gaagcttctc caccaactac atatacattt ttaactttta atctctttaa ttcagccaaa
    47761 gttttttcat ttatttgaga gcttccagtc aataatatag gagcgttttt cttgtatgca
    47821 aatggtgttg cagccaaagc atctgcaatt gctgaatcgt ttattaaaac tgcattttca
    47881 gcattttccc aacctgcttg acttatctta atagaagttt catatctatc agttcctgta
    47941 agtgcacttg catttacttc atcttgatat gtaacctcaa atctagcatt tggacttcct
    48001 aagaaaacaa ttacgcctcc ttttggcaat ctaactctat tgttctttgt aactaaagaa
    48061 tagtttacag gaacaccttt atcatcataa acagcaaaag ctgaattttg aggaagatta
    48121 acttctattt ttttatttgc gatatcgtca ccaatcttat accattttgc ataaccattg
    48181 gattctagtt cacaagtaaa agatttttct gctggcaaat tagttataga atcttcacta
    48241 acatacgtta gtgttccaaa agataaatac tctgtaccat tttctttatg aagtttaatg
    48301 tcggataaat cacgacctat tacaccaggt atttctataa aagcatttga gttattctca
    48361 tccattattt tagtgttaac tatataacct ggagtttcat cagaaagagc aagagttgcc
    48421 ttcacagaac caaacatata gctttgagaa gtatattttt catctactag atagtaatct
    48481 ttaccatttc tttttttcca tgcttctttt acactatttg atatattgtt gtcatctatc
    48541 ttttgagcta catagtataa acttgctgtc tgacctaatc cagggacatc atcataagag
    48601 ctcatattta aatatgtgat attgtttttt tcttttacaa attttagaca gctgttacct
    48661 ttttcagata caaatctatc ttgacctatg tatacgtatt tatcttcagg tccattttct
    48721 atataaggag aagatactgt taaagtacca ttatcattaa catctacttt tatcatattt
    48781 gaagaagcat aaagaccact attttctttt agagagctag gcattttaac ttgttgtggt
    48841 ttactaaatg ttttatcagg ttttatttct ttaattttac ctttttcttt taatgcagat
    48901 agtaagattt cttgtccaat tatttcatta agttgactac ttccaccaga agaaagaact
    48961 gcaactgcca tattttcatc tggaagaact ataagattac tgtggaataa taaagagtct
    49021 ccaccttttg taagagcttt taaattatac tgattaaatg
//
LOCUS       DAEHWO010000022        49020 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEHWO010000022 DAEHWO010000000
VERSION     DAEHWO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49020
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.022"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            117..827
                     /locus_tag="KNP54_001518"
     CDS             117..827
                     /locus_tag="KNP54_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892424.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            821..2137
                     /locus_tag="KNP54_001519"
     CDS             821..2137
                     /locus_tag="KNP54_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBF0892425.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            2149..2289
                     /locus_tag="KNP54_001520"
     CDS             2149..2289
                     /locus_tag="KNP54_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBF0892426.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            2348..2929
                     /locus_tag="KNP54_001521"
     CDS             2348..2929
                     /locus_tag="KNP54_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBF0892427.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            3076..4785
                     /locus_tag="KNP54_001522"
     CDS             3076..4785
                     /locus_tag="KNP54_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892428.1"
                     /translation="MSSIKAISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKINSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            4800..5672
                     /locus_tag="KNP54_001523"
     CDS             4800..5672
                     /locus_tag="KNP54_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0892429.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLIDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            5673..6461
                     /locus_tag="KNP54_001524"
     CDS             5673..6461
                     /locus_tag="KNP54_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892430.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVSYIARKSTVLKKSK"
     gene            complement(6557..7390)
                     /locus_tag="KNP54_001525"
     CDS             complement(6557..7390)
                     /locus_tag="KNP54_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBF0892431.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNCA
                     KKDNRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(7458..8087)
                     /locus_tag="KNP54_001526"
     CDS             complement(7458..8087)
                     /locus_tag="KNP54_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBF0892432.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            8397..9056
                     /gene="cprR"
                     /locus_tag="KNP54_001527"
     CDS             8397..9056
                     /gene="cprR"
                     /locus_tag="KNP54_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBF0892433.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            9267..10325
                     /locus_tag="KNP54_001528"
     CDS             9267..10325
                     /locus_tag="KNP54_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBF0892434.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPEKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            10576..12720
                     /locus_tag="KNP54_001529"
     CDS             10576..12720
                     /locus_tag="KNP54_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:10990..10992,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HBF0892435.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            12769..13602
                     /gene="fdhD"
                     /locus_tag="KNP54_001530"
     CDS             12769..13602
                     /gene="fdhD"
                     /locus_tag="KNP54_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBF0892436.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            13613..13786
                     /locus_tag="KNP54_001531"
     CDS             13613..13786
                     /locus_tag="KNP54_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892437.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            13844..14395
                     /locus_tag="KNP54_001532"
     CDS             13844..14395
                     /locus_tag="KNP54_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBF0892438.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            14420..15796
                     /locus_tag="KNP54_001533"
     CDS             14420..15796
                     /locus_tag="KNP54_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBF0892439.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFSVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            15796..16311
                     /locus_tag="KNP54_001534"
     CDS             15796..16311
                     /locus_tag="KNP54_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBF0892440.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(16389..17672)
                     /locus_tag="KNP54_001535"
     CDS             complement(16389..17672)
                     /locus_tag="KNP54_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBF0892441.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            17860..18282
                     /locus_tag="KNP54_001536"
     CDS             17860..18282
                     /locus_tag="KNP54_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBF0892442.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            18384..19322
                     /locus_tag="KNP54_001537"
     CDS             18384..19322
                     /locus_tag="KNP54_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBF0892443.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            19508..21532
                     /gene="ligA"
                     /locus_tag="KNP54_001538"
     CDS             19508..21532
                     /gene="ligA"
                     /locus_tag="KNP54_001538"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBF0892444.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            21692..23041
                     /gene="rph"
                     /locus_tag="KNP54_001539"
     CDS             21692..23041
                     /gene="rph"
                     /locus_tag="KNP54_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBF0892445.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRTIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            23041..23511
                     /locus_tag="KNP54_001540"
     CDS             23041..23511
                     /locus_tag="KNP54_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBF0892446.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            23705..24991
                     /locus_tag="KNP54_001541"
     CDS             23705..24991
                     /locus_tag="KNP54_001541"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBF0892447.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            25141..25725
                     /gene="clpP"
                     /locus_tag="KNP54_001542"
     CDS             25141..25725
                     /gene="clpP"
                     /locus_tag="KNP54_001542"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBF0892448.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            25744..26994
                     /gene="clpX"
                     /locus_tag="KNP54_001543"
     CDS             25744..26994
                     /gene="clpX"
                     /locus_tag="KNP54_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBF0892449.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(27065..27592)
                     /locus_tag="KNP54_001544"
     CDS             complement(27065..27592)
                     /locus_tag="KNP54_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBF0892450.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(27580..28092)
                     /locus_tag="KNP54_001545"
     CDS             complement(27580..28092)
                     /locus_tag="KNP54_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBF0892451.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            28272..30635
                     /gene="lon"
                     /locus_tag="KNP54_001546"
     CDS             28272..30635
                     /gene="lon"
                     /locus_tag="KNP54_001546"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBF0892452.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            30625..31236
                     /locus_tag="KNP54_001547"
     CDS             30625..31236
                     /locus_tag="KNP54_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBF0892453.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(31501..32871)
                     /locus_tag="KNP54_001548"
     CDS             complement(31501..32871)
                     /locus_tag="KNP54_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0892454.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGSVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(33046..33161)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            33449..34528
                     /locus_tag="KNP54_001549"
     CDS             33449..34528
                     /locus_tag="KNP54_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0892455.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            34919..35599
                     /locus_tag="KNP54_001550"
     CDS             34919..35599
                     /locus_tag="KNP54_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBF0892456.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            35592..36971
                     /locus_tag="KNP54_001551"
     CDS             35592..36971
                     /locus_tag="KNP54_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBF0892457.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            37142..38227
                     /locus_tag="KNP54_001552"
     CDS             37142..38227
                     /locus_tag="KNP54_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBF0892458.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            38281..38640
                     /locus_tag="KNP54_001553"
     CDS             38281..38640
                     /locus_tag="KNP54_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBF0892459.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            38693..39565
                     /locus_tag="KNP54_001554"
     CDS             38693..39565
                     /locus_tag="KNP54_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBF0892460.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKNIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRGFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            39566..40009
                     /locus_tag="KNP54_001555"
     CDS             39566..40009
                     /locus_tag="KNP54_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892461.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            40024..40608
                     /locus_tag="KNP54_001556"
     CDS             40024..40608
                     /locus_tag="KNP54_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892462.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            40861..41898
                     /locus_tag="KNP54_001557"
     CDS             40861..41898
                     /locus_tag="KNP54_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBF0892463.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLNGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            41979..42344
                     /locus_tag="KNP54_001558"
     CDS             41979..42344
                     /locus_tag="KNP54_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892464.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            42349..42666
                     /locus_tag="KNP54_001559"
     CDS             42349..42666
                     /locus_tag="KNP54_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892465.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            42714..44318
                     /locus_tag="KNP54_001560"
     CDS             42714..44318
                     /locus_tag="KNP54_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892466.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            44442..46070
                     /locus_tag="KNP54_001561"
     CDS             44442..46070
                     /locus_tag="KNP54_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBF0892467.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            46335..47684
                     /locus_tag="KNP54_001562"
     CDS             46335..47684
                     /locus_tag="KNP54_001562"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBF0892468.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            47840..48919
                     /locus_tag="KNP54_001563"
     CDS             47840..48919
                     /locus_tag="KNP54_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBF0892469.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
BASE COUNT        20091 a         5101 c         8498 g        15330 t
ORIGIN      
        1 aagctaaaat taaaatctaa atagctattt actacagaag tatgttaaaa tatgtaaaat
       61 gaatagaaat ttatatattt ttattaaaaa tatataagaa aggatgttta agaattgtga
      121 ttaatatagg aatatgtgat gatgaactac attatcgaat aaaaataaaa gatatattaa
      181 gtgaaatatt aagttcatat cctataaatt ataacatata tgaattttca gcaggagaag
      241 agttactaaa taactatcct aaagatttag acatattaat tatggacata caaatgaaaa
      301 caataaatgg tatggatact gctaggaaga taagagagtt tgatcataag ttagaaataa
      361 tatttgttac ttcatttgta gagtttatgc aagaaggtta tgaggtaaaa gcatacagat
      421 atatactaaa gccaataaat aaagaaaaaa tttctaaaag tgtattacct tgtataaatg
      481 agatgatgaa aaagagaaat aattacttaa ctataaatgt aaaaaattat gtagaccgaa
      541 ttaaaataga ttctattact tatatagaaa cagatagacc gaatatattg atttatacac
      601 atgatgatat gtatattact aaaatgagta tatctaaaat agaaaagata ttaaatgaat
      661 atggattttt tagatgtcat aatagctata tagttaactt aaaattagta gaatcaatga
      721 gtggaagtac tgttatagta gatggaaaaa gtattccaat aagtaaatat agggttaaag
      781 gcttgaagct tgcgataact aatatattag gggacatagt atgctaacaa atttaagtgt
      841 aggattttgg aatattatta atttagtttc aggtactata gattggatta tatttttttt
      901 agtaatccac ttagttggaa agaggaaaat atctaatata agatatatat ttacaacaat
      961 aattataatt atatttatgg catacataaa tgtagttaaa gtgtttccaa atattaagat
     1021 tcttctatgt atggtaatag gaatatcatt ttatataaca tcatatgaag ataaaatcta
     1081 taaaagtata atagttagtt tattgttttg gctaggatta atggttgctg aaggttctgc
     1141 agtaggtcta gtagtattta taaataaatt aaataatatt aacataacac aacatgaaaa
     1201 cttatttaga atacaagcta ttattatgtc aaaggtattt ttatttatag gttttatatt
     1261 gtttaagtat tttaaattat ctttagattt taaacctaaa gatatgatac taataggaat
     1321 acctatatta tctaatatag ttagcttatt acttatattt gaatataatt taagagtcaa
     1381 tacaattact acagaaaact tatttatatt tatatttgca attttattga ttttatcatc
     1441 aagtataata cttttaatag taatagggaa aattgtacaa gacgataaat taaatctaga
     1501 gtatgaactt ataaatgaaa gaataaaaac aaactacagg aattatgaaa atataaacga
     1561 agttcatgat agattaaaat atgtttatca tgacttgaaa aaccatatga tttgtataaa
     1621 aaattatgac actaaagaag aaattatatc atatataaat aacttagagt ttcagataag
     1681 tgaatttgaa cattttaaaa atactggaaa taaaacatta gatttaattt tagcagaaaa
     1741 aataagtatt tgtaaaaagt atgatattca aattgaagat aacataaata tatctaaatt
     1801 aaactttatt aaaaataatg atatatgttc aatatttgca aattcactag ataatgcaat
     1861 tgaagcatgt atggatataa ataatgagat agaaaaaaga atagaagtta aagctacata
     1921 tataaataaa tttgcaataa taaaatttat aaatactaag gtaaatgata ttaaacttat
     1981 tgataaacgt attcaaacta gtaaggatga tgataagata catggaatag gacttgctag
     2041 tattaaatat atagtaaata aatatggtgg tgaaacaata gttaattact cagataatga
     2101 gtttatatta aaaataatga taccaataaa aagttaggag agtacaaaat gaaaaaaata
     2161 gcgttaaact tacttaaaaa catctcagca ttaagttttg ggatagctgt attatcagca
     2221 aacagtgcaa gttcttgggt agcacatcag gcaaaagagc cacaagcttt acaaaaacta
     2281 aaaaaataac attaataaaa ggacctcttc ttattaaagg agaggtttta catgttgagg
     2341 aggaaatatg tttaaaagat tatcatataa atttgccaat atattagtta ataatgagat
     2401 tgtagaaagt gaagattttg aaatatatag atatggattt gaaactttga tttatttcat
     2461 agttaatatt ttggtagcat tatttatagg aattattttt gatagattta tacatacagt
     2521 tatattttta agttgttatt gcactttaag acagttcaca ggaggttatc atgctaggaa
     2581 ttataaagag tgtacattaa catttgcagt tatttatttg ataactattt tttcagctaa
     2641 taatatagat ataaataaat ataagtattt attagtatta ttaatgatta ttagtatact
     2701 aacaatttac aagttagctc ctttagaaca tagaaacaaa cctcttagtg aaagtgagaa
     2761 aaagcattat agaaagactg tgcaaaaaat actattcgta ataatatgtt taattatttt
     2821 atgtaaaata cttaatattt ttcagcaata tgtgatttat gcaataattt ctatatattg
     2881 gattgctata ttaatatata ttggaatgaa ggttaatagt gatcagtaag attataaaac
     2941 attttctaaa ttaattaact tcactaatta atattaactt taaaaaaata atgtcaaggt
     3001 aagtatttga acttattaaa tatagttgaa tctattgtag gttgtatcaa aagactggct
     3061 aggaggggca taaatatgag tagtattaag gctatatcag actttataac caaaataatt
     3121 agaaaaaata ttttatttgc aataacaatt attattataa attaccatct catacaacga
     3181 tggacacata tatccaatag aggaatttca tttaatgatt acttatcctt gagtgtatat
     3241 acttgtatga caattagtat tttaaccatg ttaaatgtaa ttttttatat gagaaaaagt
     3301 tatgatactg taaaaatatt atgtagaaat aattttgatt attttttagg tatttctgtt
     3361 gctgtaacta gaaacaactt tatattttgt tgcataccaa ttatatatgc tatagcatac
     3421 tcaagtttaa taagaacatt gtcaattgta acgattaaat caactatatt tatattgata
     3481 tttgaatggt ttttaccact tactatttta tctatagtga tatcatttat ttcagttatt
     3541 ataaataatt taatactaaa gattacctta tcatcagtat ttttatattt aacatcaact
     3601 aatatgttgg atagagttat tgatattaaa gaaccatttt ttaaagcatt atttaaatca
     3661 cttaacatat ttgaagatca atcatatgct tactattctg attttgtagg gaaagttaat
     3721 aattcagcat atgttataga taagattata cctacactat ttgcaattac tttaataata
     3781 gtagcatatc tgatattaaa tgatattaga aagaaacaga ttaaatcatt aatagttata
     3841 gtagtgtaca gtattttatt tattggatta aattatatat caatagatat gtcaacatat
     3901 agagatgagg agcgtagtta tggagagtat ttaaagaaat ctaatattag tgatattaaa
     3961 ataaaatcgc atgatatgaa gattgacttt aaaagcaagt caaatataaa agatagaatt
     4021 gttttattaa acacatcaaa tgaagagtta acaaatatta atatgatttt agatgaaata
     4081 tttgatataa aatatataaa aataaattcg gaaaatataa aatttaacaa aaaaaaggat
     4141 ttaattgaag ttaatttaaa ggaaagttta gagcctaatg acgaggtgac attagatata
     4201 gagtatgaag gctatattaa tgtgttgaca tcttggaatc aaaataaata tatagctact
     4261 aaagatgata ttatgcttcc accaggttct ttagcgtggt acccaaaagt aaatcaatca
     4321 agttgtatgg cttataaaat aaatttaagt tctaaaaata atgtctattc aaatttacct
     4381 ttactgaata agactagtaa ttttttaaaa aaagattata tatttgaagg aaagtcaaat
     4441 gatattgcaa tatatgcagg tgagtttaaa gaagaggtaa aagatgatat aaaaataatc
     4501 tatccatcag atagtaatgt aaatatggat atagaggaaa aaattaaatt tttaattgaa
     4561 acaagaaatg aaatattagg tgatagcaaa gcatctgtag atgctaaaaa atatgtagat
     4621 gaagtagata atgttatgga atcaataaaa agaaaaaaaa ttaatatgat attagttgct
     4681 gacttaccta gcaatgaatt tttatatgaa gactcaaagg gagagaaaat tagcataact
     4741 atttatcatt ggctttcagg aaatatcctt ataatagata aataataaag gaggttaata
     4801 tgataaacaa gttagaaata agaaatctaa attttaatta caaaaataaa aaagctttgg
     4861 ataatataaa tttaacccta atagatggag tagttgcatt attaggtcct aatggtgctg
     4921 gaaaatcaac attaatgagg ttattagtga ctctttatga aacttcaatt ggagagatag
     4981 aattaaataa tataaagtat agcaaaaaca atgagaaaat caaggcaaat gtaggatatg
     5041 tacctcaaga ttttgatatg tataataata taaatgggca agaatactta gaatttgtag
     5101 ctaaaatgag aggtgtatct aagaatgatt taaagaaaca tatacaaaaa gtagtatcaa
     5161 aagttaatct ggacaagttt ataaataaaa aaataggtac atactcaggt ggtgtaaaga
     5221 gacgactagg tatagcacag gctttaatag gtgattctaa gttaatagtt atggacgaac
     5281 ctacagttgg tcttgatcca gagcaaagga atgaatttag aagattgtta ccagaaataa
     5341 gtaaaaattc tatagtatta atttcaactc acatagtaga agacatacaa tttaactgtg
     5401 acaaattaat tatattaaat caaggcaaaa tattatatga tggtacaatt aataagttta
     5461 ttgatatggt tgaggtgtat tcggtagtag tttctaatga tgaatttgaa tatttagaac
     5521 gtaatattga tattattgat tataggagag ttaaagatgg tgtgcaagta aagtatatag
     5581 gtaaaaatac agagaaactt aaagatagct taaggataga tacaacttta caagatgctt
     5641 atataaactt tttacataag gagttaaaat aaatgtgtat attggagtta ataaaatttg
     5701 agcttaaaaa aatagagctt aaacatgtgt taatatttgt aattatttct atcttatgca
     5761 tatttattac aggcatatta gattataatg agttaatatt ttataatgat gtacctataa
     5821 tggatacata ttctatagca ggatggttag gaattataaa gatatcagat gtttttatac
     5881 caataatgtc agcaatcaca ataatttatg tgttttcaaa agattattcg ggtaatataa
     5941 atgagatact tactttatat aataaaaaaa aatataatca atttatagta tttagatggt
     6001 gtgttatatt agctatatat actgtattat tattaatttc aattacaata gtatatacat
     6061 ttacgtcagt gaaaggtttt aacatagaca aaatagattt tgtttatagt gtaaagccaa
     6121 tagatgtgtt tttaaagaca tttcctacat tattatggta tacaacattt ccactaatga
     6181 tattaacatt aacaaaaaat agatttacaa caatagcaat attaattaca tatacatttg
     6241 ctgatatatt ttttatttta catatgtacc catttgttag tatgattaat gtaaatggat
     6301 tttatattca aaagatgttt tatatgccta acaatataga tgttagattt aatgaattaa
     6361 agaattattt ctttataaat agaggttctc tagtagttat ttctataata atagtttctt
     6421 atatagcaag aaaatcaacg gttttaaaaa agagtaaata gtttaatata ttttttataa
     6481 tgttatattt atatagaata gtgactttaa aaaatttaaa gccactattt tttaatatgt
     6541 tttatctata taactattat ttttctaggt tttttaatat ttcgtaatag tgtgttgtgg
     6601 ctatttcact tgactcgcct tttttacaaa aagataattt agatagtttt ggaactacac
     6661 gttcaacgac aattttatta cctatcattt tagattcaag tatcttcaat gcttctaaaa
     6721 atctattatc cttttttgca caattataaa atgataaaac gtagacataa aggaataggt
     6781 tataattacg gaaaggatat tcaacttgca taaataaggt tccaattcca tagtgacaag
     6841 ggccgattgg ttttttaata gtccaatggt caagtagaaa atctacagct ttgtcaagtt
     6901 ttgattcttt atttagataa ttactaaaac ggaatgcatt taatatatta agagttggta
     6961 gtggatttga gtattcagtt tctggacctc gaccaaaact aaatttattg caacgccacc
     7021 caccatcagt atactgtgta tctaaaaaat gttgaaacgt tttttgcatt ctaatgtcag
     7081 atgcatatcc catatgacag agtacgttag cagcatttgc agtatgacaa gggtaaatac
     7141 ctccatttgg atatagtttg aaacgtccat cttctcgcca tgtgctaaat atcaagtcag
     7201 cacattcttt aagtaaagta tcatcagggt tcacacctaa ttctaataga taaagtacac
     7261 tatcaagagt agagaaagga gaacctttta ttaaacgctt atcaggtgta gtccaatagt
     7321 ctgcaccatt atcatacctg tgtgataata ttatttcaat atctgataaa gattgatttt
     7381 ctacattcat tttttactcc atttcatatt atattctatt aaatctatca aaaactttat
     7441 tataatatta tttatattta taattgattt attttattta aaattgcatt tatagctgta
     7501 tcaggaacaa ctgctaaatc ttctgcattg aagtaataaa ctatattaga atcaaataat
     7561 atatttgaat ttggaggaaa ttcatcatct ccaaaccaaa gtataaatac catagatgta
     7621 ttacccatat atgtaaacct ataagctaaa tctcccatgt ttactttttc agctccaatt
     7681 ttctccataa ctaacttata tttgtctatt tgagatgtaa aaacttctga aagcctatat
     7741 agagtcctgt ttaaaaaatt tggataataa acattgcctc ctggtatttc tttaaaagtt
     7801 acatatttat tagttctagg aataccttta gcattgatta aatatctaac tatcaagatt
     7861 ttaagctcaa agttattgca aaggctacca ttactattcc aaacttctcc acttggatag
     7921 tctataatat attgtctatc aaaaaaattg agtgtgaatc tatttaaatc attattgaaa
     7981 ggtatattac ttaaattact aattgtatga gggtctaatt ctttgagttt ttttcgaaca
     8041 tagtcaaatg gaacattata attatttttt gttatctttt catccataat tttttcctcc
     8101 aatttaaaca attaaaagta tatttataaa aagttttctt attattaatt ttattatata
     8161 ttcaaaatat tacaataata aattgttaaa taaattttta tatttaagta aatacgtgta
     8221 aaatgaatat aaagttttga aatataaagt ttttgtatct aagatatttt atttgtaaaa
     8281 tagtaattaa ttattgtaag ctataatatg agagtattat ggttaatgtg aattttaaag
     8341 atattattaa atatataaat tagaatacta ttaaacggat aaatggagga gttattatgt
     8401 ctaagatatt agtagtagat gatgagttag atatgttaaa gttgattgaa aatgtgttga
     8461 aaagagatgg acatgaagta aaggtaatta gtgatgtaga aaaagctatg aacatggatt
     8521 ttaattattt taatctaata atattagatg ttatgatgcc taagatggat ggttttgaag
     8581 tatgtaaaac tataagaaat aaggttgatt gtccaatact gtttttgaca gcaaaaaata
     8641 tggaaagtga tattatgtac ggtcttggta taggtgcaga tgactatata accaaacctt
     8701 ttggtgtagg agaattaagg gctaggataa ctgctcattt aaggcgagaa agtagagaaa
     8761 aaaagaattt attaactatc tcaaatgttc aatttaactt tttaggcaaa gaagtttcaa
     8821 ttgatggtaa aaaaattaat tttactaaaa gtgaatatct aatatgtgaa tttctagcaa
     8881 aaaataaggg acaagtattt tcaaaagaaa gaatatatga gtcggtatat ggttttgatg
     8941 gagaaagtga tataagtact atcacagagc atataaaaaa tatacgaagc aaattaaaac
     9001 aatatgatat ttatacaata gaaactgtat gggggatagg gtataaatgg gtgtaataag
     9061 tataagtgtt gtttagtgaa aatattatat atatctacaa aatgtttgta aaatattaat
     9121 ctatatatta aaatttaatt tatagattaa tattttttgt aaatgacaaa attgtaaggt
     9181 attttgttat aaaatattaa gattcatagt gtatactaat aatatagtat ttagtataaa
     9241 tcttgagcaa aggatggtta tttctaatgg atagactaaa gaatattaga aagagtttac
     9301 tacagtatac atttttattt ttgttaatag gtataacaat ttacctagtg tttaaaacat
     9361 tggatattaa aatgctatca aatgttatgg ttatggtaga taagaagttt ttattcatag
     9421 gtgctttggc aataatgtgt cacataatgc ttgaaggagt agtaatgaag ataattatag
     9481 aaagcactca caaagttaat attagattta ttggttttaa gctagccatt atgggatttt
     9541 attataattt aataactcct tttgcttcag gaagccaacc agtacagata tatgtactta
     9601 aaaaatgtaa aatgccactt agtaaggcaa gtgcagttgt taccaataag tctattatct
     9661 tccaaatagt agttactttt tattgtacaa tacttgtttt aatgaatttt gctatgttag
     9721 aaaaacaaat gaaaatgatt atgcctctag tgtttctagg gatagccatt aattcatttg
     9781 tcttaattat gataatatta gttattttaa atcctgaaaa aataaaatat tttatgagaa
     9841 ttactataaa gcatttatca aaaattaagt ttttaaaatt tttagataat aagattgaat
     9901 ccatagaaag ttttatagat gattatagta aagcaataaa tttttttgca aagaataaaa
     9961 aggtattaat ttcaactata atagtaactt ttattcaatt aagtgcttac tttagtgttt
    10021 cattttggat atataaagca tttaatttac aaggttatag ctatatttat atactgacat
    10081 tacaagcatt tttatatatg gcaatatctc caataccaac acctgggaat gtaggagcta
    10141 atgaattagc ctttttcact atattcaaat cagtattccc tcaacctttg atgggatatg
    10201 cagtattttt atatggtgga tttatgtact atttgattct gattggaagt ggaatattta
    10261 ctgtaattac tcactataga atgaaaaaca gaattggcag aaatattgtt ttaagtgaaa
    10321 actaaataag tttaaagaat atatattgag tatattaaaa aatatgtcat aagaactaga
    10381 atattttaat taaatggttg aaatataaag attattatga catatttttt ttgaaattta
    10441 agaggaattg tgagaaaatt gttgaattta atagatagta ttgcaaaata tttatgattt
    10501 tgcatattat aaaaacactc attatcttta agataaattt tacttatcag gggataaatc
    10561 taagggggga attgtatgga gaaaaaaatt ttaacagttt gtccatactg tggagctgga
    10621 tgccaattat atctagtagt aaaagataat aagatattaa gagctgaacc ggctaatggt
    10681 agaacaaatc aagaaagttt gtgtttaaaa ggtcgttatg gatgggattt tctaaatgac
    10741 cctaaaattc taacacctag gctaaaaaag ccaatgataa gaaaacaagg tgtactagaa
    10801 gaggttgaat gggatgaggc tataaactat acagcttcaa gactaaatga aattaaagaa
    10861 aaatatggac ctgattctat tatgggaaca ggttctgcaa gaggacctgg taatgaagca
    10921 aactatataa tgcaaaaatt tatgagagct acaataggaa ctaataatgt tgaccattgt
    10981 gctcgtgtct gacatgcacc atctgtagcc ggtctggctt actcattagg tagtggtgca
    11041 atgtctaatt ctataccaga gatagaaaat gcagatgttt tatttatatt tggatataat
    11101 ggagcagatt cacatccaat agtggcaaat agaatagtaa aagctaaaaa aaatggtgct
    11161 aaattaattg ttactgaccc tagagtaact gaatctgcaa gaattgctga tatacatcta
    11221 cctataaaag gtggaacaaa catggtttta gtaaatgctt ttggaaatgt attaatagaa
    11281 gaaggtcttt acaataaaga atttgttcaa aatcatacac aaggatttga tgagtataaa
    11341 gaaattgtta aaccatatac agctaaatat gctgaaaaga ttacaggaat cccagaagag
    11401 cttataagaa aagctatgag agaatatgca aaaggtaaaa aagctatgat actttatgga
    11461 atgggtgtct gtcaatttgg tcaagctgtt gatgtagtta agggacttgc atcaattgct
    11521 ctacttacag gtaattttgg tagagaaagc gttggaatag gacctgtacg tggacaaaat
    11581 aatgttcaag gagcttgtga tatgggagct cttcctaatg tatatcctgg ctatcaaaat
    11641 gtaactgatg ataagataag agaaaagttt gaaaaagctt ggggggtaaa attatctcct
    11701 aataatggtt atagtttaac tcaagttcca aatttagtac taaaagagaa aaagcttaaa
    11761 gcttattata tatttggaga agacccagta caaagtgacc cagatgcatc agaagttaga
    11821 gaagcattag atgaattgga atttgtcatt gttcaagata tatttatgaa taagacagca
    11881 cttcatgctg atgttatact tccagctact tcttggggag aacatgaggg agtatataca
    11941 tgtgcagata gaggattcca attgatgaga aaagctatag agccacaagg agatgtaaaa
    12001 ccagactggc aaattataag cgaaatttct acagcaatgg gatatcctat gaattataaa
    12061 aatactaagg aaatatggga cgaacttaga caattatgtc caagtttctt aggtgctact
    12121 tatgaaaaga tagaaactca aggatgcgtt caatggcctt gtaagagtga aagtatggaa
    12181 gataaaggaa ctatgtatct gtatgaaggt caaaagtttt ctactcctaa tggtaaaggt
    12241 aatttgttcg ctgctgaatg gagaccccct atggaagttg aagatgatga atacccattt
    12301 agtttatgta ctgtaagaga agttggacac tattcagtaa gaacaatgac tggtaattgt
    12361 agaacactta gttcattaga agatgaacca ggacgtgttc aaataaattc taatgatgct
    12421 gaaaaattag gaattgaaga tgatgaatta gttagaatta gttcaagaag aggaagtgta
    12481 ataacaagag caacagttac tgatagagtt aaggaaggtg caacatatat gacttatcag
    12541 tggtgggttg gagcttgcaa tgaacttaca atagcaaatt tagaccctat atctaaaaca
    12601 ccagagtata aatattgtgc tgttaaactt gaaaaacttg aagaccaaga attagcagaa
    12661 aaatgtgtaa gagaagagta tcaaagtttg aaagacaaaa tgacagctac aaatatctaa
    12721 tgatttatta gatttaagat ttataaaagg cagaaaggct aatattttat gaacaatata
    12781 tactcaaaaa ctaaattaca agaaaatagt aaggataaag tttttgaaaa tagttatagt
    12841 ctagtggact acaaatattt aaattctttt aatgtagaag taagcaaaat aaatgaacat
    12901 gaagtatcaa tagataatga agaaataatt gcagaatatc cacttagttt tattttaaat
    12961 gataaatatg taaatacatt tttatgtacc ccatataatt tagaggaact tatagtagga
    13021 ttcttgaaaa caaaaggata catagaaaac aaaaaaagct tattaaaatt tgagataaat
    13081 gagagtgaac gttttgcaaa agtaactatt caagagaaac aaaaaaatca agatgagcaa
    13141 attatatttt taaattcact agactatata acatgtgctc ctgtaaagag caatataaaa
    13201 ataaattatg atacgattta cagtataatg gataaaaatt taaattcatc agaattattt
    13261 aaaaatactg gtggggtaca tagcgtatct gtatttaatt ttgataaaaa aatagtcact
    13321 tgtgaagatg tagcaaggca taatgcaatg gataaggcta ttggattttg tgttttaaat
    13381 gacataacat taaaagataa aattgtggct gtaagtggaa gaatatcatt ggaaatgata
    13441 ttaaaagcag ctatgactca aattcctatt gtagtatcaa aatcagcacc gactaattta
    13501 tcaatagagc tttctaaaaa attaaatata acgcttattg gatttgtaag aggaagacgg
    13561 atgaatattt atgcaaatcc acagagagtt atcaaaaagt gagaatgaat atatgtgtac
    13621 taaaaaagaa gagcaaagat attcaaagtg tgaaatctgt ggagtattaa ttgatgatac
    13681 tgataaggtg tataataaca catacaattt gtgcaaaaaa tgtaaacgaa atataagtac
    13741 tgagaaaata gtgaaatata taaatatata tgatgaaagt aagtagacat atgatgaaaa
    13801 taactagagg gttggaaata tacaaattga aaggtgggat aatatgaaaa ataaaatagg
    13861 ctcttttgta atagcagacc caaacaaatg tacaggttgt agagcttgtg aagtagcttg
    13921 ttttacaatg cataatcagc ataataatgt gggttataca gttggaacag ttgatatacc
    13981 tgttatacct agactttact tagtaaaagg tgacaatttc tgtatgccaa tacagtgtag
    14041 acattgtgaa gatgctcctt gtttaaactc atgtccacaa aaagctatag ttaaagaaaa
    14101 caatattatg tctgtaaatg aagaaaagtg tataggatgt aaaacttgtc tgctagcatg
    14161 tccttttgga gctatagact tacttccaca atatgaagat ggtaaagaag tagaacaagt
    14221 aattttagat gaaaataaga agatagctta taaatgtgac ttatgtaaag acaatgaaaa
    14281 aatagcttgt ataagtgcat gtcctcagga agcattaaaa cttgttactc caatagatga
    14341 caaaaaagct aagaatagac aagctgcact tagtttattg ttaacaaata aataaaggat
    14401 acaggggtag gtgacgttta tgataataaa tatagataag gatttatgta ctggatgtag
    14461 agaatgttca aaggtctgtc cagtaaatgc tattgaaggt gaagagggaa agccacaaga
    14521 gataaattta gatagatgtg ttatgtgcgg tcaatgtgtt caaacttgta aatcttatgc
    14581 ctcagttata gatgaaggat ttgagttttt acaagagaaa aaacaagaaa gagagatacc
    14641 agagtctata aatgaaccta tatttgcagc atacaatgta tgtgatatag ataaggtgaa
    14701 gaaagcttta agtgacccaa atgtattcac tatggtccaa tgtgcaccag cagttagagt
    14761 tgctttagga gaagattttg gatattattt aggatactta ggtgctggga aaatggcagc
    14821 agcacttaga gctttaaatt ttgatagagt ctacgatact aattttgcag cagatttaac
    14881 tataatggaa gaaggtagtg aattaattaa aagagtgaca gaaggtggaa ctcttccaat
    14941 gtttacatct tgttgtccag cttgggtaaa attcatggaa aaaaattatc ctaaattaac
    15001 taatcattta tcttcttgta aatcacctca gcagatgggt ggtgcaatat ttaaaactta
    15061 tggtgcagag ataaataatg tagatgcatc aaagatattt agtgtttcta taatgccatg
    15121 tacatgtaaa aaatatgaat gtgatagaga agaaatggat tctagtggat atagagatgt
    15181 agatgtagta ttaactacta gagaactagc ttatttaata aaagacatgg gaattgattt
    15241 taaaaattta agagaagaaa aatttgatag tcctttaggt agttatagtg gagctggaac
    15301 tatctttagt gttactggtg gggttatgga agctgctata agaacaggat atgagcttat
    15361 aactggagaa agtattcctg atgtagaagt aaaacaagta agaggagaaa atggttttag
    15421 aaagtcaact attaaaatag gagacttaga cttaagagtt ggagtagtaa gtggattaaa
    15481 aaatgtaata ccagttcttg aagacttgga aaaaggaaaa ttagatgtag attttattga
    15541 agttatgact tgtcctgttg ggtgtgtaag tggtggaggt caaccaaaaa ttttactaga
    15601 agaatataag gaattggctt atgaaaatag aacaaaagca acatacgtgc atgatgaaca
    15661 tttagcaatt agaaaatctc atgagaatcc tgatattaaa aaactgtatg atgaatatct
    15721 ggtagaacca ttaggagaaa aatctcatca tctattacac actacatatt gtataggaaa
    15781 ggaagtggct aagtgatgaa ctattttgtt atagcagacc ctgataaatg cataggatgt
    15841 agaacttgta tgataggatg tgtagttgca cattcagatg aagatatttt ttaccaaaat
    15901 ccagatgaaa taaattttaa tccaaaactt tctgtcataa agacaaaaga agtaagtgct
    15961 ccaatacagt gtagacattg tgaagatgct ccttgtgcaa aggcatgtcc aaatggtggt
    16021 atagttaggg ttggtaacac aataaaaata aatgaagaaa attgtatagg atgtaagact
    16081 tgtatgttag catgtcctat aggtgcaata gacatagtta cattaaaaga tgtagatgaa
    16141 ggaaagcttt gctttagaga aagaatgaca gcaaataagt gtgatttttg tatagaatcg
    16201 ccagaagggc ctgcatgtgt aaatgtttgt ccaactaagg catttactat agttaaggat
    16261 gaggatatag atagtaaagt taaaaataag agaaaattag ctatattgta atataaaaaa
    16321 gatggagttt tatttatgat taaaagctcc atctttttta ttataatatt tatatatcta
    16381 aaaatcaatt attgcattag tttatctaat ctttctttat tcaatttttt cattcctata
    16441 gaagttataa taagtaaagt ataggcaatt ataactgata aaattataat agaccaagaa
    16501 aatctgtatc caaaattatc aactaacaat ccaaataatg ttgaacctaa tgcaaatccc
    16561 actgcaaaaa ttaattgtac gattccatat atgctaccaa actccttttg accaaagaaa
    16621 gagccagtta aataagcagg accaatcata taagcaaata cagaaagacc tttcaaaatg
    16681 gcaaatacaa atgcaaaagt agaagattta tctaccaata gtaatgataa agttgctata
    16741 agaaccaata caaaagatat aataagtggc tttgtttgac cgaatttatc aaacaataat
    16801 cctccaaata aattaccaat gagagcaaat aaggcaaatg tggagcctac tgttcctatt
    16861 agaataggat ttagataatt tctaagataa gttggatatt gtacagataa tgatgaaaca
    16921 tatataccaa caaatataaa tccaatagtc ataatccaaa aatatttaat ttttttagct
    16981 tcttttaatg tataacccca tactgaagga gaaattgtat cagatgcttt ctctttttta
    17041 cctttagatt ttaccttttc attaatatct ttaggcatcc tgagtatgaa taatattaca
    17101 ggtataccaa ctattaatgc tataattcca aatattagat aagaacgact gtatccttga
    17161 gttgctaata agcgaactgc aagtggttgt agaaatatac taccaataga accaccagca
    17221 aaagcaaagc ccaaagcttt tcctttgctt tcttcatcaa accaagcact tattaaaaca
    17281 ggtattccta tagcagatat aattgtagcg ccaatttgaa caatacatga tacagtgtaa
    17341 aattgccata gttcagtaca tatagaaaaa gtagcaaaag caatactaga aattatacaa
    17401 cctaataaat atagtatctt aatattgact ttagaaaata atacacctat aaaaggtgat
    17461 gcaattgctg aggcaatagt accaatagtg aatattagag aaaaagaagc taaactaaag
    17521 ccttctcctt ctacaacata acttataaat tgaggctgta tacttgctac aatactaaat
    17581 ggaacagctt gtattaacat acaaccaagt actataaccc aagcatttga aaagttttta
    17641 atgctaaatt tattgtttag taatgtattc atggtatctc tcctttaggt tatgatttgt
    17701 agatattaat ctaattattc taattttata tattagtttt ggatagccta actatttaaa
    17761 tataatttgg gtattaatat aaaaattaac tataaaaatt gattatttta aatgtatggg
    17821 gtaaattaaa gtatataaat aaatgaaagg atggataaaa tgtcatttga aaaaataaat
    17881 aataataacc tagataaaat acacaatagg aagtgtatta tgcttgtaaa ctttaataaa
    17941 aaagaattat cattaattaa aaatgtaagt aactttgctg gaataagaga ccatatcatc
    18001 ttaagtgata aaaatggaga gaatataata agagacattt tagatggaaa tatatcaaat
    18061 gaatgtgaaa atgggattaa gagtaagtct gtaatattta ataacactcc aagtacacaa
    18121 gtaaatgcat ttttagaagg gctaaaaaaa gtgagaataa atagaccttt tacagctatg
    18181 gtaacagaga catctattga ttggacattg aataatttaa tagaaaattt agttcaagaa
    18241 cgtaatgcta tgtctttagg aaaaacaatt gaacataagt aaatttaaga tatcttatag
    18301 taattttaac taatgtacat tgagtatcat attatatttt agaatagaaa attttaaatg
    18361 tgggtagatg gaggagattt gagatgaaag ttttatttac aataaattat ggaaaagaaa
    18421 aatttgataa aataagagaa ttaggctatg atgtcataca ttactctgaa gatagtattg
    18481 aaaataatga ggatgtaaat acagcagatg tactagttac atacaatcca tttgagagat
    18541 tagatatttc taagatgaaa aatttacaat atatacagac aactagtgta ggtatagacc
    18601 aacttccaaa agaagaggta ttgaagagaa atattaagat agctaataat agaggcggat
    18661 atagtgtacc tattggtgaa agtattgtat tgtatatttt agaaatatat aaaaatagtg
    18721 caaaattttt taaacaacaa caaaataaag aatggaagat ggatttttct gtatcagaat
    18781 tgtatggaca aagagttgga tttttaggaa caggtactat atcttcagaa gcagcaaaaa
    18841 gattaaaagc ttttggtgta gaaatatggg gtgtcaatac tgatggaagt agtaaaaaat
    18901 actttgataa gtgttttgct actgaggata tgaatattgt atttgaagaa tgtgatatag
    18961 tagttgtagc aatgccttct acaaaaagta cagatggaat agtaaacaaa gatatgttta
    19021 aacttatgaa agatggttct gtatttataa atgtaggtag aggaaataca gttaatcaga
    19081 aagatttaga agaatgtgta gagaaattta gaggggtagc attagacgta tttgaaagtg
    19141 aacctttaaa caaggacaat aagttgtggg agtgcgaaaa tgtcatagta actcctcata
    19201 attcttgggt gtcagataaa aacaaagaga gaacatttaa tatggtttat aataatttga
    19261 aacactatat aatggagaat aaacctgtag ataatgttgt agacatatca agaggctatt
    19321 aaaaataaaa aattttgata aaaataaaaa ctcttattag tcgtattaaa gatactaata
    19381 agagtttttt ttgtaataaa tttaaagccc aaaaagtgat atactaaaaa atatataaat
    19441 aggagataat taattatagg gaaatttcaa aataatttaa ttttaaaaat atgaagaggt
    19501 gcaaaaagtg agcgtaaaag atgaaattaa taaacttata gagacaataa actaccataa
    19561 tgaaaggtat tataatcaag atagcccaga aatatcagat tatgaatacg ataagttaat
    19621 gaaggagtta atttctttag aagaagaaca tccagaacta aagagaattg attctccaac
    19681 aaatagggta ggaggtaagc cattagataa gttcaatcaa attgtacata aaactcctat
    19741 gttgagttta tcaaatgctt tttcagagca agatttgaga gattttgata agagagttca
    19801 agaatatgtg ggagaaaatg ttgaatatgt tgttgaattt aaaatagatg gtctttctgt
    19861 aggtctaact tataacaatg gagagtttga aaaaggagca actagaggag atggagttgt
    19921 aggagaagat atttctcaaa acttaatgac agtaaaaagc atacctctta agataaatga
    19981 taaaaaagaa ctaatagtta gaggagaagt atatatatca aaagataatt ttagaaaagt
    20041 aaatgaacaa caagaagaac aagaacagcc attatttgct aatccaagga atcttgcagc
    20101 tggttcattg agacaattag acccaaaact aacagcaaag agaccattag atatatttgt
    20161 atttaatatg gaaaatatag aagaatacga tttagaaagt cacagtgaat cactagagta
    20221 cttagaaaaa ctaggatttt cagtaagtca gagttataaa gtttgtaaaa gtatagatga
    20281 agttattgag catattgaat actggacaga taacaggggt aatttagact acgaaataga
    20341 tggtatggta ataaaagtaa acaatataaa acaaagagac gaaatgggat atacagccaa
    20401 aagtcctaga tgggcaattg catataaatt cccagcagaa aagaagaaaa ctaaaatagt
    20461 agatataata gtagaagttg ggagaactgg tacaataaca ccttcagcaa ttcttgaacc
    20521 agtcagactt gcaggtacca ctgtaagtag agctacactt cacaatgaag attatataag
    20581 agaaaaagat ataaaaataa atgatacagt attagttcaa aaagcagggg acataatacc
    20641 tcaagtttta gaagttataa aagaagaacg tactggagat gaaatagatt ttaaaatgcc
    20701 agaaaagtgt ccagtttgtt cagagccaac aataagatta gaaggagaag ctgctgtaaa
    20761 atgtatcaat atgtcttgcc cagcccaaat aagaagggga attatacact ttgtgtcaag
    20821 ggatgcaatg aatatagatg gattgggaga atctataatt acactgctat taaatgaaaa
    20881 aattattcaa gatgtatctg atttatatta tataaaaaag gaagatgtag tcgacctaga
    20941 gagaatgggc gaaaaatctg ctgacaattt aataaattca attgaaaaat caaaagaaaa
    21001 tgatttatgg agacttataa atggattagg tattaaattt ataggagtta aagcagctaa
    21061 gatacttgca tataacttta aggatttaga tgaagtaatt tctgcaacta gtgagcaact
    21121 agaagaatta gaggaatttg gaagtataat ggcaaacagc gttgtcgagt tttttaagga
    21181 agacaaaaat atgaacgtta taaacaagtt aaaaaatgta ggagtaaata caaaatcatt
    21241 ggataataca ggtgaaaaag tagaaaaaat atttgaaggt atgaaaatcg tattgactgg
    21301 tacacttcct acattaaaaa gaaatgatgc aaaagatatg atagaaaaaa gaggtggaaa
    21361 agctacatct agtgttagta aatcgacaac atttgttttg gcaggtgaag aagctggttc
    21421 taaacttact aaagcaaatg atttaggaat taaagttata gatgaagaga gatttttaga
    21481 attattaaag ttatcatcga aagatgaagt aaaagctgta ttagagagtt aaaaagtcgc
    21541 ttaatttagt agaaaactac tataattaat gatagaatag ttcagtaagc taataagatt
    21601 acgaaaaatg acaataatta atatttgaca aaattaaaaa ttataaaaat aaatttataa
    21661 aaaataaaaa atatgagaaa ggatataaaa aatgaccaga agttatgata gaagtaatga
    21721 acagataaga cctgtaaaga taactagaga ttatacaaag tatgcagaag gttctgttct
    21781 tatagaaatg ggagagacaa aggttatatg cactgcatca gtggaagaaa aagttcctcc
    21841 ttttttaaga aatagtggta ctggatggat aaatgctgaa tattctatgc taccaagagc
    21901 aacacaacaa agaaagataa gagatgcatc taggggaaaa attgatggaa gaacacaaga
    21961 aatacagagg ttaataggaa gaacaataag gtctgttgta gacttgaata aattaggaga
    22021 aagaactatt tgggtagatt gtgatgtgat tcaggcagat ggtggaacta gaactgcatc
    22081 tataacaggg gcatttgtag cagttgcaga agcaatatat aaattatata aagcaaagac
    22141 aataaaagag atgccaataa caaattttgt gtctgcaatt agtgttggta ttgtaaatgg
    22201 aatacacatg ctagatttat gttatgaaga agattctaaa gcacaggtag atatgaatat
    22261 aataatgact gataagtgtg agtttgtaga agtacagggg acaggagaag agaaaccttt
    22321 ttctagagca gatttaaatt tattgttaga gttaggtgaa aaagggaata aagaattaat
    22381 aaggcttcaa agagaagctt taggtgaaat atcagatgag atattgggta tggattatgg
    22441 taatgaagta gtgattgcta ctaataatgc tcataagcta gaagaaatag gtgaaatctt
    22501 aaaagatttt gaatataaag tgtactcttt aaaagatgtt gatttagcag gtatagagat
    22561 agtagaagat ggaaaaacat ttgagcataa tgcgttgata aaagctagaa caatagcaaa
    22621 aaagactaaa cttatagcaa tatcagatga ttctggctta gaagtagatg ctttaggcaa
    22681 aaaacctggt gtttattcag ctagatatgc aggagaacat gcaacagatg aagaaaatag
    22741 aaaaaaactg ttaaaagcta tgcaaaatgt accaatgagc aaaagaaatg caagattcgt
    22801 ctctgcaata gcagtagttt ttcctgatgg aaaagaattt gtagtaagag gaatttgtga
    22861 aggaatgata ggatttgaag aaaaaggtaa aaatggtttt ggatatgata gcttatttat
    22921 agtaaaagga tatgataaga cttttggtga aatacctagt gttataaaaa attcaatcag
    22981 tcatagagca aacgcactaa aacttatgaa acaagagttt ataaaaaggg tagtgaagta
    23041 atgaaaatag gcatagtaag cgacacacat atgatgatta aaaatatgga aaaaacaata
    23101 ccatatttga aagaatgtga cctaataatt catgcaggag ataactttac tgattcaaga
    23161 tatattcata gcatgactaa tgtaggtatt attgcagtta aaggtaattg tgactttgat
    23221 gctgttgagg aagaagttgt ctttgaagtg gcaaataaaa ccatattctt atgccatgga
    23281 gataagtatg gtgtaaaata tggaactaat atgttagaaa aaaaggcaac tgaagttgat
    23341 gctgatatag ttatatttgg ccatacccat accccattta gagaaattaa agatggtgta
    23401 ctttacataa atcctggaag cacttcactt ccaagaggag tatcgtataa aagttttgtc
    23461 attatggata tagaagaaga tgacataaaa attgaagaaa tacgcatata aaggtgtatt
    23521 tatctaaaaa aatggcaaaa aacgctcaaa aaattaaatt ttatcaaata agtacaacga
    23581 tattaatgga acacttgtaa ataaaaaaac ttatgtgata taattaagtg gttgaattat
    23641 aaatagaatg aattataata ccgttatcgg gtattacata aatatcacta ggaggattag
    23701 aaggatgaaa gcagaactaa ttaaaaaaga gggtaataaa gttactttaa aaataacagt
    23761 agataacaat aaatttgaag cagcagtaaa taaggcttat aataaaagca gaaataaata
    23821 caatatacct ggatttagaa aaggtaaagc tccaagaatt gttatagaga ctcaatacgg
    23881 aaaaggtata ttctacaatg atgctataga aatattattc ccagaagttt atccagaagc
    23941 tatcaaggaa ttagacatag acccaataga caatccagat ttagatatag aagaaataag
    24001 taaagacaat gggttggtta tggttcttaa tgtagaagtt aaaccagagt ttgaattagg
    24061 aaactacaag ggtatagaaa tagctaaggt tgagaatact gtaagtgacg aaaatgttga
    24121 tgctaaacta caagaaatgg ttgaaaaaaa tgccagatta gtaagtgtag aagacaaagc
    24181 tttagaagat ggagatacag ctataataga cttcgaaggt tttgaaaatg gtgtagcttt
    24241 tgatggtggt aaaggtgaaa attataactt agttataggt tcaaacacat ttataccagg
    24301 atttgaagaa caattagtag gtaaaaaagc tggtgaagaa gtagaagtta atgttacttt
    24361 cccagaagaa tatcactcac aagatttagc tggaaaacca gttgtattta atgtaaaaat
    24421 aaatgatgta aaagtaaaag aattatctgc acttgatgat gaatttgcta aagatactag
    24481 tgaatttgat tctttagatg aattaaaagc agatgtaaga gctaagttag aagaagaagc
    24541 taaaaataga gcagatgcag aaactagaaa ttcagtagta gaaaaagttg ctgaaaatac
    24601 agaaatagaa ataccagaag ttatgataca acatcaaata gataatatgt taaatgaact
    24661 taactaccaa ttacaatatc aaggatttgg attacaacaa ttactagaga tgactggtag
    24721 aactatggaa gaattaagag aagagagaaa agaagatgct aaaaaattag ttaagtcttc
    24781 tttagtatta gaagcaataa ctaaagctga aggaattgaa gcaacagaag aagaatttaa
    24841 ggctgagtta gaaaaaatgg cttctgctta caatatggaa gtagaaaaaa tagaagcttc
    24901 tttaagagat gctgacaaag aagatataaa aggtcaaata aaaataagaa aaacaataga
    24961 tttattagtt gataatgcaa caatagctta ataaaataaa cgctaactaa tatagttgac
    25021 gttatgaaat gtttagtata taatgatgtg caaatataat ttagttaaat gcgtataata
    25081 atttacagta gcttaaaaaa agctactgta aattatatag aataaagggg gtatgaaacc
    25141 atggcattag tacctgtagt tgttgaacaa acaggaagag gagaaagatc ttatgatatt
    25201 ttttctagac tattaaaaga cagaataatc ttcttaggag atcaagttaa cgatgccaca
    25261 gcagggctta tagtagcaca gctattattt ttagaagctg aagacccaga caaagatata
    25321 catttatata taaattctcc aggaggaagt ataacttctg gaatggctat atatgatact
    25381 atgcaataca tcaaaccaga tgtaagtact atatgtatag gtatggctgc ttctatggga
    25441 gcattcttgt tggcagcagg agcaaaagga aaaagactag cactaccaaa tagtgaaata
    25501 atgatacatc aaccattagg tggagctcaa ggtcaagcaa cagatataga aattcatgca
    25561 aagagaattt taaaaataaa agaaacttta aatgagatat tatctgaaag aactggtcag
    25621 ccattagaaa aaattaaaat ggatactgaa cgtgataact tcatgagtgc actagaagcc
    25681 aaagaatatg gtttaataga tgaagtattt acaaagagac cgtagataga gagaggtgtt
    25741 aatatgtcta aatatgaaga aaaacgacaa ttaaagtgtt cattctgcgg taaaaatcaa
    25801 gatcaagtaa gaagattaat tgcaggtcca aatgtatata tttgtgacga gtgtgttgaa
    25861 ctttgtgacg aaattattca ggaagaaata gaagatacta tagatgaaga tactacatct
    25921 ttaccaaaac caaaggaaat gatggagatt ctaaatgatt atgtaatagg tcaagaaaaa
    25981 gctaaaaaag ctttatcagt tgcggtttat aatcattata agagaatata cagtaaaaaa
    26041 tctagtagta aggatataga aattcaaaag agtaatatac ttttattagg acctacaggt
    26101 tctggaaaga cattacttgc tcaaactcta gcaagaactc taaatgtacc ttttgcaatg
    26161 gcagatgcta catcattgac tgaagctgga tatgttggag aagacgttga aaatatactt
    26221 ttaaaactta ttcaagctgc tgattttgat atagaaaaag ctgaaagagg tataatatat
    26281 atagatgaga tagataagat tgcaagaaaa tctgaaaacc catctataac tagagatgtt
    26341 agtggtgaag gtgttcaaca agcacttcta aaaatattag aaggtactgt tgcaaatgtt
    26401 ccaccacaag gaggaagaaa acatcctcat caagaatttt taaagataga tactactaat
    26461 gtattattta tattaggtgg agcttttgat ggattagaga agataattca aaaacgtggt
    26521 ggagataaaa cactaggttt tggagctaaa atagaaagta aaaaagaatt agatttaggg
    26581 aagctgtatg aaaaagtact tccagaggat ttattaaaat atggtataat accagagttt
    26641 ataggaagaa taccagtttt agctacttta gagttgttgg atgaagatgc attaatgcag
    26701 atattacagg aacctaaaaa tgctctagta aaacagtata aaaagttatt ggagttagat
    26761 gatgttgagc tagaatttga agaaggtgct cttcgtgcaa tcgctaaaaa ggccatagaa
    26821 agaaatacag gagctagagg acttagaagt atagttgaaa gcgtaatgat ggaaactatg
    26881 tttgaagtac catctagaga taatataaag aaggttatag taacagagaa atctgtgaac
    26941 gaagactcag taaatcctat catagtactt aaggatcaag aggaaagtgc ataagatgat
    27001 gaaaaggagc tttaaaagct ccttttttta tgttaatatg ctaaatataa aataggtatc
    27061 attattataa aaatgtgagt aatataccta gaataccaaa gacgaataca attgcaatgg
    27121 aaccaatttt tcctttatat aaaagataaa atgatgctat aaatgcaatt attccatata
    27181 aatcccaatt aacttctttg gcagatgaaa aagctgctga taatatgaat cctagagtaa
    27241 ttggtctaag aactgtcaat aagttttcta cctttttatt atttttaaat ttagaaaata
    27301 actttgatat aatagttaga cctattaatg caaaaattgt aacaccaata gttgcagcta
    27361 gagaaccaaa gaagccagca gtcttaaatc ctacaaatgt agcactattt attgctacag
    27421 gacctggtgt agattgtgat atagcaagta aatccaaaaa ctcttgatta gttataaagt
    27481 gatatttaga tataaattct tgctggataa atggtagcat ggcataaccg ccaccaaaac
    27541 taaatgcccc tattttaagg aatattaaga agagtagtat tatttctgac atagactata
    27601 tacacctcct ccaattatta aataaatagg gcttatattg aatacaccaa cagataaaac
    27661 tgctataatt aatagtagta tgttagtttt agactttggt agtttcttga acatgctcgt
    27721 aaaagaatac aatataagag ctattacaac aggcgcaact cctttaaaaa atccatctaa
    27781 aattttagat gatgaatttt taaagtatag atacgataag actaagacta tacaaaatga
    27841 tggtaaagca gagcctaagg tacatataag aactcctggt ataccataaa gtttatatcc
    27901 taataataca gatatattaa ctgccagtac tccaggataa ctttgagcta tggataaata
    27961 atcaataaat tcttcctgct ctaaaagttt ttgtttgttt acaagttcat cttgtataag
    28021 aggaaccata gcgtatccac caccaaatgt aaacgcacca atttttaaaa aggttaaaaa
    28081 caatttcaac ataatagaaa cctccaaaag ataaataaca tctaagtata ctaatattaa
    28141 tattatatca taataaaaag ataatatagt atgatagtat tctaagaatt tatcattaat
    28201 gttgaaaatt aacttgttca aatatataat attaaaagca aagcaattag actagaaaag
    28261 gagtaatgtt gatggaacaa aattatacta aaatagatca tgaattacca ttaattcctc
    28321 taagaggatt agctatattt ccatatatga tattaaattt tgatataggt agagagatat
    28381 ctcttaaagc tttagaccaa gctatgatgg atgaagaact tatattttta acttctcaga
    28441 aagaagcaga ggtagatgag ccaggagaag aggattttta tcatgtggga acaatctgta
    28501 aagttaagca aatgataaaa ttaccaggag atacagttcg tgttttggtt gaaggtgtat
    28561 caaggggtag agtaaagaaa atagaacaag aagatgggta tttcagagca gtaatagaag
    28621 aaatagtatt tgatagtgat aatttggata gtgaaacaga agttgaaatt gaagcatttg
    28681 taagaaatgt atttgatgcc tttgaagagt atataaatat tggaaatagg gtatcaccag
    28741 aaatattaat atctttagct gatatagaag atgtagatag atttatagat acgatagctg
    28801 caaacatata tctaaaatca agccaaaaac aagaaatatt agaagaattt gatattagaa
    28861 aaagacttga acttatttat tctatattat tagaggaaat agatatatta aaaatagaaa
    28921 agaaaataac tttaagagta aaaaaacaga tgaataaggt tcaaaaagaa tattatctta
    28981 gagaacaatt aaaagctata cagaaagaat taggtgaaga agaagatata aactctgaag
    29041 cagatgagta tagagaaaag cttaaaaaaa taaaagcacc taagacaact aaagagaaaa
    29101 tagaaaaaga gatagataaa ttttcaaaaa tatcttctat gtctccagat gtatctgtaa
    29161 gtagaaacta tttagatact atattctcat tgccatggaa taaagagaca aaagataaat
    29221 tagatataac taaggcaaaa gatatattag atgaagacca ttatggatta gaaaaagtta
    29281 aggagagaat actagagtat ctagctataa gaactcttgc taagtcactt aaagggccta
    29341 taatatgtct agttggtcct ccaggaacag gaaagacatc tatagtaaaa tcaatcgcca
    29401 gagcattaaa tagaaaattt gtaagaatat ctttgggtgg agttagagat gaagcagaaa
    29461 taagaggtca tagaagaact tatgtaggtt caattccagg aagaataatt aatggggtaa
    29521 aagaagccca aacaaaaaat cctgtattct tatttgatga gatagataag atggcagcag
    29581 attataaagg tgacccagct tcagcaatgc tagaagtatt agacccagag caaaataagg
    29641 attttgtgga ccattactta gaaatacctt ttgatttgtc aaaaatacta tttgttacaa
    29701 cagcaaatag tctaagtaat ataccaagac cattattaga tagaatggaa gtaatagaag
    29761 tatctggata tatagaagaa gaaaaattaa atatagcaaa aaaataccta cttccaaaac
    29821 aaattaaaga acatgcttta aaagaaaact ttataaaaat agatgatgaa actttaagaa
    29881 gtataatcaa ccattataca agagaagctg gtgtaagaac actagaaaga actattggta
    29941 agatttgtag aaaggttgcc aaaaaatacg ttgaagaccc aactcttgaa gaggttgtta
    30001 taaataagtc tgacctagag acatatcttg gaaaagacat gtttaagtat caacttgcag
    30061 aagttaaccc tcaaatagga ttagtaaatg gtcttgcatg gacagaagtt ggtggagtta
    30121 cacttgaagt agaagtaaac gtacttaaag gtaaaggaga aattgtatta actggaaaat
    30181 taggagatgt tatgaaggaa tctgcgaaga caggtatctc ttatataagg tcaatagtgg
    30241 acaagtttga tatagaccct gaattttata agacgaatga tattcatata cacattccag
    30301 aaggtgctgt tccaaaagat ggaccatcag ctggtataac tatggctctt gcagtaatct
    30361 cagcacttac taaaagacct gtgcctggaa atatagcaat gacaggagag ataactttaa
    30421 gaggtagagt cttagcagta ggaggagtta aagaaaagtt attagcagct catagagctg
    30481 gtataacaaa agtattaatt cctaaagaat gtgaagctga tttagatgaa ataccagaaa
    30541 atgtaaaaga aaaaatggag tttgtgcttg tagaacatat ggatgaagta ttagaacaag
    30601 ctttattaaa gagtggtgaa aataatgaaa attagaagtt cagagataac tatgagtgct
    30661 gtgaataaat cacagtatcc agcagaagga atcccagaga tagcattggc tggtaggtca
    30721 aatgttggaa aatcatcaat aataaataca ttgcttaaca gaagaaactt cgctagaacc
    30781 agtcaaacac caggaaaaac tagaactata aatttttatc taataaataa tgaattttat
    30841 tttgtagacc ttccaggcta tggatatgca aagatagcta agtctgaaaa agaaaagtgg
    30901 ggaggtataa tggaacgata tctagaaagt agacaagagt tatgttctat attcctactt
    30961 gtagatatta gacatgagcc tacagcagat gataagctta tgtatgaatg gataaagcac
    31021 tttggatata actgtgtagt tattgcaact aaggcagata aaatatctag aggacaatat
    31081 caaaaacaca taagtataat aagaaaaaaa ttgcaaatgg aaagtagtga aaaagtaatt
    31141 cctgtttctt cactaaaaaa gactggtgtt gaagaattat gggaagagat tgtaaatcaa
    31201 tacaatcaac atggatatga aataacagta gattaaattt aaaatgttaa atattgacat
    31261 gagatttatt tgaataataa atgtaataat agttagtttt aattatatta atattaaagc
    31321 aaaatatagg atgccttaaa atagttttaa tgaacttttt ttggcatcct tattgtttat
    31381 aaacaataaa tatcagtaat tttgttaaat actaataaat tttagtaagg tatgggaaaa
    31441 ttagtataaa ttagttcaac taaaaaatta ttgacttatg tagtcagcaa taaatagcat
    31501 ttaagaaata gatttatctg tttttctcat aaagaaaaca gttagtataa gccctataaa
    31561 acatactgat gctgcaatcc aataagactg attgctagct ataacatagg ctgatgtgtg
    31621 acttttaaac ttttgattgt atgtaagact ttgtgcaaaa aaactactaa aaaatgctgt
    31681 tccaagagca aatgataaat tacgaatagt tgcaagaaaa ctgcctccgt atccctgttt
    31741 ttgaggagga acatctgcta aaatactact attgtttggt gaactaaatg ctcctagccc
    31801 aagtccaaaa ataactaaac atacaattaa aagatacaat ggagaatctg cttttaaaag
    31861 tgccattcca actagtgaga tggtcataaa tgaaaaagat gctgttagaa tgttttttgc
    31921 accgtgttta tcagaaagtg aacctgcaat aggtgctata agtaccataa taagtggatg
    31981 tacagtcatt acataaccag ccatcatagg agataaattt tttaattgtt ctaaataaaa
    32041 tggaagtaga aaagatactg ccatttgagg aaaataacaa gctactccaa tgatattgcc
    32101 tacagtaaag tttctatttt taaatagagg taggtcaata aagctttgtt caaattttac
    32161 ttctcttaat gccaacaata agaagattat aagtgctgtt atacctaaat acaatcttgt
    32221 attacccttc tcattcattg caagtaatat aagcgtagtg caagatgcga aaagtagaag
    32281 acctggaata tcaaagctct tgttttgttc atccaaaaca ggtttaggta gaaatttaat
    32341 gccaagaaag actgctataa taccaatagg tatattgata ataaaaatag aaggccatcc
    32401 aaaatgttct aaaattatac ctccaattac agaaccactc atatttccta taccaactac
    32461 agctccagtg attcctatag cttttccttt ttcatttgct ggaaatgcat tggaaactat
    32521 accaagccca gtagccatta aaatacttgc tccaactgcc tgaaagattc ttgaagaaat
    32581 taatgttgat aaattgtttg acatactaca cagaaaagaa cctattgtaa atataaaaaa
    32641 tcctaatgtg tatagacgat ttgaacctac tttatcgcca agttttccga aaaataacat
    32701 agtagctgtt acaacaagca tataagctgt tacaacccac tgaatttgtg acatgttaat
    32761 tttaaagtca gcagcaattg taggatttgc gatatttagt atacttccat caagagtaga
    32821 cataaataca ccaatacaga tgataatcaa tactatccat ttttgtttca tgataacact
    32881 ccaatcttaa tagattttat aagtacgata taattgtaaa ataaacaaca aaaaaagcac
    32941 ctgtatatta ggtaccttga atgtgtctaa tttcatgaat aaatacggta gttgaaggat
    33001 ttgtatagat tactcatgta aaattacata aaggtactca tatactattt tcttctacca
    33061 tccagatttt actgtcggct ttggaatatg accaaattat gccataaggc tcgcgggctt
    33121 ttaccgccga tagggaattt cacccgttta tgaagaaaaa cagatgtatt ttgtaatatt
    33181 attttaacat aaaattataa tggaaacaat tggatttaag taatatccag ctgtattaca
    33241 atacaaatat ttcaatatgg acacttaaat tgtatttata gatagaataa ggaacagtat
    33301 gagaatctat aataattaga taaaattaac ctgttattag tattagatgg taagttttaa
    33361 atttatcaaa atcagaaagc tgtaataaaa ttcttataat atgaatatct taattaagag
    33421 atattgtaaa ttatgaggag gcgctaatat ggaaggaaag gtaaagaagg cattcccggg
    33481 tggaaataca tcacaaggct catattcttt ttttgactat ataattcctg aaaatgtaaa
    33541 aagagttttt tgtttaaagg gtggacctgg agtaggaaaa tcctcactta tgaaaaaaat
    33601 ttataaagag tttttgcata gaggatatga tattgattta tatcattgtc cttctgaccc
    33661 aagttcgttg gatggtttag ttataaagaa attaggcgtg gtacttatgg atgcaactgc
    33721 cccacatact atggacccaa agctacctgg agctttggat gagataatta atttaggtga
    33781 ttactggaat acagaagaat tagaaaagaa taaacaagaa atatcagttt atgataaaga
    33841 tattagtaat tcatttaaaa gagcatttaa gtttttaaaa tcagcagaac caatctttag
    33901 agacatagaa gaaaaatatt ctgattgtat ggattatgga aaagtaaatt tggtcacaga
    33961 agaatttata aaaaggttat ttgatggagt taaaagcaca ggaaatctaa aaagagaaaa
    34021 gcatttattt ggttcagcta taactcctgt agggtgttta gattatacag aaaacatttt
    34081 aaaagatgta aagaaagtct attatttaga tggagaaata ggaactggga aaactacatt
    34141 attaaacaaa gtatataaga aagctattga aaaaggttta aatgtagaag tttatcatta
    34201 tccacttatt ccagagaaaa ttgaaactgt actattaact gatttagata taggcataac
    34261 tataagtacg acttttaaag aagaagatac aattgattta aatcagtttt taaatagaga
    34321 aaaactactt aaatatgaag aagatattaa atttgatgaa aaagttttag atgatttaat
    34381 ttgttgggca gtactaaatc ttaagagagc caagtctaaa catgatatta tagaaagtta
    34441 ctatagtcct aatatgagat ttgatgaagt agggaaatta agagataagt taattaaaag
    34501 aattttaaaa tatgaggaaa acttataaac gcatatgttt aaaattaacg ttagtaataa
    34561 tataattttt agtaaattgg tgtagctttg aggctatgcc attttacttt ttttgctaaa
    34621 aaatgatatt aataatctcc aaagccatta tttgtttttc ataattatta tttcctttcc
    34681 taatttatgt ttttttataa tatcacaaca atgtttattg aaagtttata taattttaag
    34741 aacatctaaa aatgcatact tgatattggt aaattagtga taggagttca atgtatgata
    34801 ttatatacta aagatgaatt ttaatatata actttgatat aataagcata tgtaaatgtt
    34861 taatatttaa ttaaagaaaa ttatcatata aaaataaatt tgtaaggagc aatacagtat
    34921 gaaaaaacaa tatgtgttta taatactagc aagtactatt ttaggtatac ttgttggaac
    34981 catatttaga gattatagca atgaagaaac agtttataca agcaaagaca agtcaataag
    35041 aaaagaaata aaaatgacaa gaaaatctat aaaagaatta accaaagaga aagacaagtt
    35101 agataaagaa attaattcaa tgaaacaaaa tcaaaaaaat tctgaagaaa tatcagaaat
    35161 agaaacactt agagatagtc tatcatattc agatgtaaag ggtagtggga taatattaag
    35221 tatagatgct atagatgaaa aaacagggaa tatagctaat agtatagact ataataagat
    35281 tcttgtaaaa gttataaatg aattaaaagt aaacggagga aaatacatag aaataaatgg
    35341 tcaaagaatt aatcaatatt cagaagttgt acttgcagga agccatataa atataaatgg
    35401 agttcctgta gcacaaccat atgaaataaa gtgcattgga gataaggaga aactatctaa
    35461 ttatgtagat aaaggtagta aatatttaga tagcatacaa accaattatc caatgaaaat
    35521 aagcataaaa actgaagaaa atatctctat gaaaaaaatg aatataccta ataaattaaa
    35581 gtatataaag ggtgattaag attatattag aggaaagcag tttgccaatg ttaataccag
    35641 aaaaacttgc aaaaaaatat aatgtatttc cagttgagtt tcaagatgat aatttagttg
    35701 tagaaataga agatgaggat atttatgctc tacaggactt gagattagct acaggtaaag
    35761 aaattatatt gaagaaggag aaaaaagaac ttataagtga aaagattgaa aaatattata
    35821 atagctttga acttgatgag gattatgcaa aaaaattatt tgaaaatctt ttagaaaaag
    35881 ctataaaaga aaacgcaagt gatatacata tagaaccatt taaagaacat ttaatagtga
    35941 gaatgagggt agatggagaa ctaaaggaag tatcaaagtt tttagttgat gtctatccat
    36001 cattgtctac ggttataaaa ttaaaggcat caatggatat aacagaaaaa aggcttcctc
    36061 aggatggtag ggtggatata aagttaggtg gaaatttaat tgacattaga gtttcatcaa
    36121 taccaactgt ctatggtgaa aaaatagttt tgaggatact taatagagat acttttttaa
    36181 aagacaaatt agaacttggt ttttcagagg aagctataaa atctataaat cgtataataa
    36241 ataaaagagc aggaatatta ttagtgacag gtcctacagg tagtggaaag actacaacag
    36301 tatattcctt attaaatgat ttaaaaggaa taaataaaaa tattatgact atagaaaatc
    36361 ctgtagagta taagatggat ggcataagtc agattcaagt aaattcaaaa gtagggttga
    36421 gctttgatgt aggtcttaga gcgatattaa gacaagaccc agatataata atggtcggag
    36481 aaataagaga tgcagaaaca gctaagatag cagtaagagc agctataaca ggtcatttag
    36541 ttataagtac tttacatact aatgatgcag tatcttccat agctagatta ctagaaatgc
    36601 aaataccacc atatctttta aatgcctctc ttataggtgt tatatctcaa aagttggtta
    36661 gaaaagtctg caatcattgt agccatgaga ttatgataaa agataatttt agtggagatg
    36721 taaatactaa ggtagctgta gggtgtgaaa aatgtaatga taaaggatac tttggaagaa
    36781 cagcaattta tgaaatctta gaaattaatg atgatataaa gacatgtata agaaatatgg
    36841 aggattctag tactattaaa gatgtagcac aaaataatgg aatgataaca tttgaagata
    36901 gttgtaaaag actaataaat gaaaaaataa cgacattaga agagtgttta gtagtaaatg
    36961 aaatgattta actgaattgt atagttaaac ttcgtttggt cagttgtctt tatttaatct
    37021 attttaatta agatgtttga gtataaatta tatttaagtg aaataaaatt aaatgcatta
    37081 aattagaaaa tattaagttt atttaattgt aattaatata atttggaagg tattatagta
    37141 catgagatta tctaaaaata tattttataa tttagaaaag ttttatttag tattaaatag
    37201 aatcagtgat aaagaaatta gagtaatttg caaagagata ggcatattgc tggaatctgg
    37261 atgtgaaatt acaaaaatat ttgaaatcat tgagagtcag tcaagtaaaa aagtaaagaa
    37321 cttgcttagt atagtatcaa atcatattca aaaaggtaac tcaatagcag aatcatttca
    37381 aataacaggt atattttcta aattctttat aagtatgata aaagcaggag aaactagtgg
    37441 aaacttagat ataataatga gtgatttatc taattattat gataaagaat acaaattaaa
    37501 aatgaaaata ataactattt caatatatcc aataatactt ataatattat ctatcttatc
    37561 aatgttgttt atattcgtat ttgtaatacc taattttcag gtggttttta ccaacaatgg
    37621 aattgaacca cctttaataa ctagagtttt aatgggaata tctacagtgg ttacaaataa
    37681 cttagcttat ataatattta gttttatatt gttttcaata ggaagcattt atttctttat
    37741 aacaaatgat aatataaaaa aattgattaa ttcgttaaaa ttcaaaatac cttttataaa
    37801 aaaaattaat cagttagtag ctacaacaag attttcaagg gcattgtccg ttttaattag
    37861 cagtggaata caaattgtgg aagctataga tatgtcagct agtgttatag acaacgaatt
    37921 tatttatgaa aggttaaaga tttctaataa ttatataaaa aaaggaaata gcataggtaa
    37981 atctttgaat ttagcaaata tttttccaaa attatttatt tcaatggcaa atacaggaga
    38041 agaaagtggg aaactagata aaagtctaaa tgtaataaat aaattttatg aaaatgaatt
    38101 aaataacaaa atagagcaaa taatgaaatt tatagaacct atgctaattg tatttatggg
    38161 attaattatt ggtactttta ttttagcaat ggttgttcct atgtttgatg caattactaa
    38221 tttttagaga gaaaaataaa ttttattaga tgaaactttt gaaaaggaga gaatatttaa
    38281 ttgataaatt tgataaataa aaaacgaaaa ggatttacac ttgttgaaat gattgtagta
    38341 gtaactattt taggcgttat atctagtata gcattagtta agtatagtaa ggttcaagaa
    38401 agtgccaaat taaatgcaga ctatacgaat gctgctaata tagtaaccgc agctagcatg
    38461 gcaattaatg atgatgaaaa gacaatagac tctctaagtg tagagacatt gaaggaaaag
    38521 ggatacctaa atactgttcc agttcctcag agtacatcag gtaaattcga acttgtcata
    38581 aatgatagcg gaacagatat aagcgtaaat ataaattcta agcaatttta tccaaaataa
    38641 tattttatat tgattgctgt aagttttaaa attattttta tttaagaagg agatggctat
    38701 aattaaaaaa attctaaact tagaaataaa tgatgattat ataaggcttg tatttttaag
    38761 aaaaagtcat aaaaaagttt ttatagataa atcaattata aaagagatta actttgatat
    38821 aaaaaatgat agtaattcga ttgagaagat taaatatata gaagatgtag ttagatttgt
    38881 aaaagaggag attggtaaat caaaaatatt atataaaaat ttatacttta acattcaaat
    38941 tcaggatata gtcattagaa atgttgaagt tctaaatact aagaaaaaaa gagacatatt
    39001 aagcatgatt gaatttgaaa taacacaata cattccaata aacataaata actattcaat
    39061 aaaatataaa gttataaatt ctaaaaatga taaattgaat atacaagtaa ttcttttccc
    39121 aaagaatatt attcaattaa ttaagaacat ttcagaaaat ctaaatatga atccaaagac
    39181 tataaatata aattttgata tattacaaaa gcttataaac ttaaatttaa tagagaattt
    39241 ttcagaagaa ggggtattta tagaatgtaa aaaaagtcag ttaattataa atataacaaa
    39301 agataaaaaa ataagagaaa catacttgct atcaaaagag ggaaaatcat atgagttcat
    39361 aaaaagatta ttaaggggtt ttaagtatgt ttattactat ggtatagaaa attgttttat
    39421 tgaagaatac tttaaatata cagataaatc tattgaagta aatccattaa gattaaaaga
    39481 taaagtaaaa gtagaaaata attttgatgc agatttagaa gacaatagga taaattatat
    39541 aaatagtata ggaatgatta tttaagtgaa agtggataaa acaataaatt ttcttaatgg
    39601 atttaaaaaa actaaaccat gtaataaaat ctataaaata ataatagtct taattttaac
    39661 gtgtatttta tttaaatcat ttatgtatgt gaaatctata aatgaacttg aagattatat
    39721 aagtcaaaat aagctagtgg ataaatcaaa gaacacttta ccaacaacag ataaaactag
    39781 agagaaattt tctaaaataa aacttaatga aataaaaaaa atatatgaaa caattggaat
    39841 aaatagtatt actaaaatat caatagataa aaataagcta gagatggaag gtgtgtgtag
    39901 tgatttagat gttttaaaca atttaaggaa aataaagtac ataaaatatt attacataga
    39961 cagtattgta agagatggag aatattatag atttagaata aaaagttaga tgggtgatta
    40021 tttttgagat taaataatag agaaaaaaat ctacttaaaa tattgttaat attagttatt
    40081 atattggcaa gtgatatagc agtaagttat ttggaagaaa acctaactag tttgaagaat
    40141 gaaaagcaaa atataataaa taaaataaat aatcaagata attatcaaat aaaggataat
    40201 aagcatatag atgataaata tatagaaagt gttgaattaa ataaaaatga agaattgaaa
    40261 aataatttta ataactcatt tttagataaa aaaacaaata aagatatagt gttattagta
    40321 gaaaatgaac tgagagatat tgtgaatgta gaatatatta atcaagaaag tagtttagat
    40381 aatcacaata aaaaacaagt taatttagaa ataaaagtta atggagaact tgcaaatgtg
    40441 ttgaaacttg aaggtgtaat gaagaagtta agactaaata ataaacttga aaagatagaa
    40501 attaacaaat taaaagtcaa taattttgat gttcaaaata ttccaaatga atataaacaa
    40561 gaaaaagaca atattgttga atgtaaaatg acagttagag tcatataaca aaaaagaata
    40621 gataaagtaa aaaactatta tcaattaata aaattttata gaggaattag ttttacgata
    40681 attcatttct acaagaggga ttgttgatga ttttatcgaa atcctaatta aagttaatat
    40741 attgtaccaa aatataagtg aatttaatag aatatttact tatactatag attgattaat
    40801 aaaaaaatgg tataataaca aattgtactt taatttaata ataagggagt ggaagtcata
    40861 ttgttaggga gaaatgagct atgcccttgt ggaagtggca aaaaatacaa gaaatgttgt
    40921 ttaaataaag atattgtttc agaaagagca tgcagaaaaa ctgaactttc acaaaaacaa
    40981 tatacagatt tatattcaaa gttatatgat tattcaagac aggataagtt taaagaagaa
    41041 tgtgaaaaag ctaaagaaat gttttatata atgcaaaatg atagtgtaaa tgaaaaattt
    41101 gaaagatttt ttaatactta tttaatacaa gaccacataa tggaaaataa aaaggttatg
    41161 acagttggtt ttcttgaaga aaatggtgca aacctaagtc aatcagaagt atcaatatta
    41221 aaaagtatgt ttgaatcata cgtaagtatt tatgaggtaa aagaagtttc tgctggaaaa
    41281 atagtattaa aggactgttt aaatggaaat gaactttgta cagaagatgt aaaacttctg
    41341 agaagtttta aaatcggaag ttgtatgata gctagaatag ttgatattga aggaactaac
    41401 atattgatag atataactat aagtatatca aatgaggtta aagatataat tttaaaggat
    41461 attatgaatc tattcaatca atatcaagat gtatacaaag atatgaagtc gttcttaatt
    41521 tatcatacac atatactata caagtatata caacagcttt tagacccaag tatagctgaa
    41581 tatttaaaga gagaaagaga taaaaacgat acaaaagtta attcagaaaa tgaattagct
    41641 gaagaagaat gtaaagtttt agatactctt aaagaaaatg tagaaaaaga aaatatagat
    41701 gcatgtatag agttttggaa tgaatataag aaaaatcatg aaaatataaa aggagctgaa
    41761 aatggttggg cagctgctgt tgaatactat gttaaaaaag aagcaggaca acctataact
    41821 caagttcaaa tatcaaagaa atacgatata agctctagta cactaggaaa gagatacaag
    41881 gatttaaaaa tatcttaatt aattataaaa agctttaagt catagataaa gaatctatag
    41941 tataatatat gtataatgtt tagaaagagg tattaataat gagtcttagt ttaggaaatg
    42001 caattgctgt atcaacgaac tttataaaat ctaacccagc tgtacctgtg tacaacggag
    42061 aagaaatata tgcagttatt tatcatatag aaataggata taataatggt gtatcacctg
    42121 ataccaaaca atatataata atagactata aagagtttga tttatctatg gataaaaaaa
    42181 atgaactaat aaatattgct aaagagtact gtaaatctaa aggtattgta gaaaacgaaa
    42241 accttgaaat aaacctttta gacaatgaag aagcagagaa cttcttagaa aaggtgttta
    42301 ataatatgaa ggttataaga ggtcttataa ctaaaaaagg ataaataaat ggactatata
    42361 ggaatagaaa atataacacc ttatgaaaat acatatgaat ttagtgtata tgaatatgat
    42421 gatgaaatca ccttaggtag tgaaaagtta tatgtatgtg aattaagggt tgtattgatt
    42481 aaagttaatt ctctgtatgt tgaaagattg cataaatcag ttgaagcaat ggtcttagta
    42541 aaaaacttga aaaaagattt agataaaaca cttgttgtaa acaaaataaa gaattttgtg
    42601 ctagatgaga tttgggtaga aaatctagta aaagagaata tagaagttat atttgtagaa
    42661 agctaggaat aaccctagct tttttatatt acaatctaag agaggaaaac aatatgttaa
    42721 gagtatctaa tgtaaaactt ggaattgata aagatatatc tttattaaaa gatgttatac
    42781 ttaagaagct aaaaataaaa gaaaaaaact tagtcaaata tagtatatat aaagaatcta
    42841 tagatgctag aaaaaaagga aaaatggaat ttgtttattc tgtagatgta gaagttaaag
    42901 atgaaaataa aatacttaac tcaaaaataa aagatgtaac aaaaataaag gaaatcagat
    42961 acgtaaatgt acctgtgggt gataaaaaat taaagaataa tcctttggta attggtagtg
    43021 gaccagctgg cttgtttgca ggtctgcttt tagctcaaat gggttatgaa ccaatcatac
    43081 ttgaaagagg tcttgatgta gacagtagaa ccaaagatat aagtgatttt tggacaacta
    43141 gaaaattaaa aaataattca aacgttcaat ttggagaagg tggagcagga actttttcgg
    43201 atggtaaact tacaactaga ataaaagata tacgatgtag aaaagtatta gaagagttag
    43261 ttcagtttgg agcaccagat gaaatattat actcacataa gccacatgtt ggaacagata
    43321 tattaaaaaa tgtagttaaa aatataagaa atgaaataat aagtttaggt ggtcaagtta
    43381 gatttaattc aaaagtaaca gatatagttg tatcaaatga ttctatacaa tctgtaataa
    43441 taaatgatac tgaaaaaata gatacagata caattatatt agctgttgga catagtgcaa
    43501 gagatactta tgaaatgttg tattcaagag gtataaaaat agttcaaaaa ccttttgcaa
    43561 taggagctag agttgaacat ccacaagatt taataaataa agcacagtac aaggattttt
    43621 ataatcatcc taggttagga gctgcagatt atagacttat agagcatgtt tcaaatggaa
    43681 gaacagcata tactttttgt atgtgtccag gaggtagtgt catagcatct gcatcaaatg
    43741 attttgaaat agttacaaat ggtatgagtg aacatgcaag agataaaata aatgcaaata
    43801 gtgcattttt agtaaatgta acgccagaag attttaagag tgataatcca ctagcaggtg
    43861 ttcatttcca gcagaagtat gaaaaattag cttttgaatt aggtggaaaa aattataatg
    43921 caccagttca gcttgttgga gattttataa acaataagac ttctttgaat ttaggaagtg
    43981 ttgagccatc atatagacca ggatatacac ttacaaattt aagtgaatgt ttgcctagct
    44041 tcgtaacaga gactatgaga gaagcgttta tatctcttga taaaaaattg aatgggtttg
    44101 caatgtatga tgctgttttg acgggagtag aaactaggtc atcatcacca ataagaatag
    44161 taagagatga aaatacttta gaatcagtga gtattaagaa tctatatcca tgtggtgaag
    44221 gtgctggata tgcaggtggt atagttacag cagcagttga tggtataaaa tgtgcagaaa
    44281 aaataataca aaaatacacc aataatacaa aaatttaaca taaacttaat gattttttaa
    44341 tatttaacat gaatttaaca ttatcactcc tataatttga taaaatacaa taggttataa
    44401 aatttttaga tacagtaatc tctttacaag gaggaaataa tttgaacatt ataataagtc
    44461 taatgggtgg attaggtctg ttcttatatg gtatgaacct tatgggagaa ggtcttcaaa
    44521 aatctgctgg gacaaagcta aaaaagataa taaaactact tactagtaac ctatttatgg
    44581 gagttttggt aggtacagga gttacagcag taatacaaag ttcaagtgct actactgtaa
    44641 tggttgttgg tttcgtaaat gcaggaataa tgactttaaa acaggcaata ggagttataa
    44701 tgggtgctaa tatagggact actgttacag cccaattggt atctttcgac ttaactggta
    44761 tggccccagt agcattaggt gtaggtatta tactttattt atttggaaat aagcctagaa
    44821 taaaaaatat agccgaaata cttataggtt ttggtatatt atttacaggt atggatttta
    44881 tgaagatggc agtggagcca ctaagagact atcaaggatt tactgactta cttgttacat
    44941 ttggtagata tccactactt ggattattat tgggatttgg gattacagca ataatacaaa
    45001 gttcaagtgc atctatgggt atgttggttg cactggcagc agaaggtcta gtgccattat
    45061 cagcagcact gccaattctt tatggccaaa atattggtac atgtgtaact tcactgttat
    45121 caagtattgg tgctaacaaa aatgcacgaa gagcagctat gatgcatcta atcttcaatg
    45181 ttttaggaac ggtgatattc ttaatattct tgaataaacc agtagtaagc atggttacaa
    45241 gttgggaccc aagcaatgtt gcaagacaaa tagccaatac acatacattg tttaatataa
    45301 tatctgtatt gatactttta ccatttacaa atcttattat aaaactagct ataaagcttg
    45361 ttcctgatag agcaggtgat atagatgaag atgaaactaa aactattaaa tatatagatg
    45421 atagaatgat agaaactcct tctatagctc ttgcaaatac gataaaagaa gcacttcgta
    45481 tgggtgagaa ggcgaaggaa agcctaaatg catctatgga agctttagta gaacattcaa
    45541 ctgaaaaaat agataagaca tataggcgag agagattaat caatgattta cagaaagcta
    45601 ttttaaatta tttacttaaa ctttcaaaag cacctttaga tgatgattca agagaagttg
    45661 tggatacttt gtttaataca gtcaatgata tagaaagaat tggtgaccac gctaaaaata
    45721 tagctgaatt atcgcaagtt gcaatagatt caaatatttc tttctcagaa gaaggacaat
    45781 ctgaacttga tgttatgtat aatagagttg tttcagcata tacttatgca ttagaatcaa
    45841 tgagaactga taatgttgat ttagcttgta aggttataaa aattgaagaa caagttgata
    45901 taatggagaa atcttgtaga gctaatcaca tgtatagatt gaacaataat ctatgtagta
    45961 tagaaaatgg agttatttat ttagacgtaa taagtaattt agagagaata tctgaccatg
    46021 ctgtcaatat agcacaacaa gttatagcaa agagattagg aaatgattaa aaataattaa
    46081 tttaaaataa tataaaattt aaaatagagg ataaataaaa gagaaacttt aaatgatacg
    46141 tttagagttt ctttttttgt aaatttattt gactaaaatt tttaaattta tacatagtta
    46201 tagcatttag aagaatcgat ttcctgataa taaatgatga gatatgtatg attttgtggc
    46261 aaacttttaa aaaaaacacc tatattttgt gttataatct ctttaaaacg aatatgctga
    46321 aaagagggat ttaaatggga aaaataaatt ttgattatag taaagctaca gagttttttt
    46381 gtcaaaacga aatagatgtc atgcaaccat atgtagatgt tgcgcacgac atgttacata
    46441 ataaaactgg tttaggaaat acttttttag gatggataga ccttcctaaa aattatgata
    46501 aagaagagtt tgacagaata aaaaaatctg ctgataagat aaaatcagac tcagatgttc
    46561 ttttggtaat aggtatagga ggctcttatt taggttcgag agctgctata gatatggtaa
    46621 gtcattcttt taggaatgga cttaaaaaag agcaaagaaa ggctccagaa gtatattttg
    46681 tagggcataa tataagctca acatatatta tggatttatt agatataatt gaaggaaagg
    46741 atatttctgt aaatgtaata tctaaatcag gaactactac agaaccagct ctggctttta
    46801 gaatatttaa agattactta gagaaaaagt atggtaagga agaagcaaga aagagaattt
    46861 atgcaacaac agatgcaagt aaaggtgcac ttagacagtt agctacagaa gaaggatatg
    46921 agacttttgt aataccagat gatgtaggtg gtcgtttttc tgtattgaca gcagttgggt
    46981 tacttcctat tgctgctgct ggacttgata ttgatgctat gatgaaaggc gcaaatgatg
    47041 ctagagaagc atttcaaaat cctgacttaa aaagtaatga tagttataga tatgctgttg
    47101 ctagaacaat tttacataga aaaggaaaag atgtagagtt attagtgaac tatgaacctc
    47161 aactacatta tgtaagtgag tggtggaaac agctttatgg agaaagtgaa ggaaaagaaa
    47221 ataaaggttt attccctgct tctgtagatt tctcaacaga tttacattct atgggtcaat
    47281 acatacaaga tggaaaaagg cttttatttg agacagtact taatgttgaa aactgtaaga
    47341 gaaatataac tataagttca gaggaagtag acttagatgg tttaaactat ttagcaggta
    47401 agactgtaga ttttgtaaat cataaagctt ttgaaggaac tctattggct catacagatg
    47461 gaaaagtacc taatttagta ataaatatac ctcaactaga tgagtataat tttggatatt
    47521 tagtttattt ctttgagaag gcttgtggaa taagtggata tttattggga gttaatccat
    47581 ttgaccaacc aggagtagaa gcttacaaga aaaatatgtt tgctttacta ggcaaaccag
    47641 gttatgaaaa agaaaaggaa gagctagaaa aaagacttaa ataattttaa atagttaagg
    47701 tttaattaag attaaaataa tataatgaaa tcatcgaaaa ggagtttact caaaatagat
    47761 gatttcattt tttttatgaa aaattgggaa aaatatattt tgataattta tattatatta
    47821 agatagggag tggtatgaga tgtcaagaag aaagaaaggg ataagtttag taatattagt
    47881 tgctataata agttcaatac ttagtagttt tctaacaata attttagtta aggacaattt
    47941 agtaagtaaa tctacaggaa gttctacgcc gatagttgta aatgatgatg gtaagagtca
    48001 aaatatttat caagcagttg cagaaaaagc tacgccatct gttgtaggta ttacaacaac
    48061 tagtgttgat actagtaata tgtttgcaat accaactgaa acacaaggtg taggaactgg
    48121 aatcatagtt gattcaaatg gatatatact tactaattct catgttatat cagatggtca
    48181 agctacaagt gtaaatgtat tattcaatga tggttcaaca acttcaggta aagtagtatg
    48241 gtttgaccaa caacttgatt tagctatagt taaggttgat aaaactggac taacaccagc
    48301 agaatttgct gatagtgaca aagtaaaagt tggagatata tcaatagcaa taggtaatcc
    48361 tcttggatta gattttcaaa aaacagttac tcaagggata ataagtggat tagatagaac
    48421 tatacaaaca gaaaaaacta atatgactgg tttattacaa actgatgcaa gtataaatgc
    48481 aggaaatagt ggaggaccat tgttaaatca aaaaggtcaa gtaattggta taaacacagc
    48541 aaaagcttct caagcagaag gattaggatt tgcaatacca atcaatacag ctaagagtat
    48601 agttgaagaa gtaatcaaaa atggaaaata tgaaaaagta actttaggca taaaaggtac
    48661 agatgtatca aattatgaag cagcaacagg tacaaaatta agtactgata aaggtgttta
    48721 tgttgcagaa gtaatatctg gttcatcagc agaaaaagct ggagtaaagg taggggatat
    48781 tataactaaa gtaggagata cagatataac aggtatgaat gatttaaata aaaagttgta
    48841 tactttctca aaaggtgcta gtacaaaaat aacagtaaat agaggcggaa aagcagtaac
    48901 aataaatgtg aatttctaaa tatgaccaga aagatagaga ctacatggta aagtgtagtc
    48961 tctattttta tttaattttt atagtatata catctaaatt aattaaaatg atgtattgtt
//
LOCUS       DAEHWO010000023        48710 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEHWO010000023 DAEHWO010000000
VERSION     DAEHWO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.023"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(41..1444)
                     /locus_tag="KNP54_001564"
     CDS             complement(41..1444)
                     /locus_tag="KNP54_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBF0892470.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(1906..3801)
                     /locus_tag="KNP54_001565"
     CDS             complement(1906..3801)
                     /locus_tag="KNP54_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBF0892471.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(4427..4570)
                     /gene="scfA"
                     /locus_tag="KNP54_001566"
     CDS             complement(4427..4570)
                     /gene="scfA"
                     /locus_tag="KNP54_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBF0892472.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(4636..4998)
                     /locus_tag="KNP54_001567"
     CDS             complement(4636..4998)
                     /locus_tag="KNP54_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBF0892473.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(5056..5349)
                     /gene="yajC"
                     /locus_tag="KNP54_001568"
     CDS             complement(5056..5349)
                     /gene="yajC"
                     /locus_tag="KNP54_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBF0892474.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(5483..6604)
                     /gene="tgt"
                     /locus_tag="KNP54_001569"
     CDS             complement(5483..6604)
                     /gene="tgt"
                     /locus_tag="KNP54_001569"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBF0892475.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(6683..7168)
                     /locus_tag="KNP54_001570"
     CDS             complement(6683..7168)
                     /locus_tag="KNP54_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892476.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(7180..8205)
                     /gene="queA"
                     /locus_tag="KNP54_001571"
     CDS             complement(7180..8205)
                     /gene="queA"
                     /locus_tag="KNP54_001571"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBF0892477.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(8523..9542)
                     /gene="ruvB"
                     /locus_tag="KNP54_001572"
     CDS             complement(8523..9542)
                     /gene="ruvB"
                     /locus_tag="KNP54_001572"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBF0892478.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(9649..10251)
                     /gene="ruvA"
                     /locus_tag="KNP54_001573"
     CDS             complement(9649..10251)
                     /gene="ruvA"
                     /locus_tag="KNP54_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBF0892479.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(10244..10753)
                     /gene="ruvC"
                     /locus_tag="KNP54_001574"
     CDS             complement(10244..10753)
                     /gene="ruvC"
                     /locus_tag="KNP54_001574"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBF0892480.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(11065..11694)
                     /locus_tag="KNP54_001575"
     CDS             complement(11065..11694)
                     /locus_tag="KNP54_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892481.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            11897..12220
                     /locus_tag="KNP54_001576"
     CDS             11897..12220
                     /locus_tag="KNP54_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBF0892482.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNKNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            12488..13342
                     /locus_tag="KNP54_001577"
     CDS             12488..13342
                     /locus_tag="KNP54_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892483.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(13528..14964)
                     /locus_tag="KNP54_001578"
     CDS             complement(13528..14964)
                     /locus_tag="KNP54_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBF0892484.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNGGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(15035..16417)
                     /locus_tag="KNP54_001579"
     CDS             complement(15035..16417)
                     /locus_tag="KNP54_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBF0892485.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(16553..17458)
                     /gene="garR"
                     /locus_tag="KNP54_001580"
     CDS             complement(16553..17458)
                     /gene="garR"
                     /locus_tag="KNP54_001580"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBF0892486.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDVKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHDN"
     gene            17854..18525
                     /locus_tag="KNP54_001581"
     CDS             17854..18525
                     /locus_tag="KNP54_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0892487.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            18628..19176
                     /locus_tag="KNP54_001582"
     CDS             18628..19176
                     /locus_tag="KNP54_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892488.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            19438..19746
                     /locus_tag="KNP54_001583"
     CDS             19438..19746
                     /locus_tag="KNP54_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892489.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(19908..21698)
                     /locus_tag="KNP54_001584"
     CDS             complement(19908..21698)
                     /locus_tag="KNP54_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892490.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(21698..23425)
                     /locus_tag="KNP54_001585"
     CDS             complement(21698..23425)
                     /locus_tag="KNP54_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892491.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(23670..23936)
                     /locus_tag="KNP54_001586"
     CDS             complement(23670..23936)
                     /locus_tag="KNP54_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBF0892492.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILTIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            24234..25346
                     /locus_tag="KNP54_001587"
     CDS             24234..25346
                     /locus_tag="KNP54_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBF0892493.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(25710..26219)
                     /locus_tag="KNP54_001588"
     CDS             complement(25710..26219)
                     /locus_tag="KNP54_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBF0892494.1"
                     /translation="MSQQNTGNVIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(26221..26868)
                     /locus_tag="KNP54_001589"
     CDS             complement(26221..26868)
                     /locus_tag="KNP54_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892495.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(26882..28054)
                     /locus_tag="KNP54_001590"
     CDS             complement(26882..28054)
                     /locus_tag="KNP54_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0892496.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYAIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            28322..29698
                     /locus_tag="KNP54_001591"
     CDS             28322..29698
                     /locus_tag="KNP54_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892497.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDEKDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDSIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(29948..30307)
                     /locus_tag="KNP54_001592"
                     /pseudo
     CDS             complement(29948..30307)
                     /locus_tag="KNP54_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(30634..31164)
                     /locus_tag="KNP54_001593"
     CDS             complement(30634..31164)
                     /locus_tag="KNP54_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0892498.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYGIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(31252..32346)
                     /locus_tag="KNP54_001594"
     CDS             complement(31252..32346)
                     /locus_tag="KNP54_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBF0892499.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            complement(32348..32794)
                     /locus_tag="KNP54_001595"
     CDS             complement(32348..32794)
                     /locus_tag="KNP54_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBF0892500.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            33100..34290
                     /locus_tag="KNP54_001596"
     CDS             33100..34290
                     /locus_tag="KNP54_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBF0892501.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            34460..35422
                     /locus_tag="KNP54_001597"
     CDS             34460..35422
                     /locus_tag="KNP54_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBF0892502.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(35544..36206)
                     /gene="zmp1"
                     /locus_tag="KNP54_001598"
     CDS             complement(35544..36206)
                     /gene="zmp1"
                     /locus_tag="KNP54_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBF0892503.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(36306..36391)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(36577..39495)
                     /locus_tag="KNP54_001599"
     CDS             complement(36577..39495)
                     /locus_tag="KNP54_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBF0892504.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     ENENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNLGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      complement(39613..39698)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(39825..41003)
                     /locus_tag="KNP54_001600"
     CDS             complement(39825..41003)
                     /locus_tag="KNP54_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBF0892505.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            41378..41563
                     /locus_tag="KNP54_001601"
     CDS             41378..41563
                     /locus_tag="KNP54_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBF0892506.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            complement(41628..44402)
                     /locus_tag="KNP54_001602"
     CDS             complement(41628..44402)
                     /locus_tag="KNP54_001602"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBF0892507.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(44574..45830)
                     /locus_tag="KNP54_001603"
     CDS             complement(44574..45830)
                     /locus_tag="KNP54_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBF0892508.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(45902..47404)
                     /locus_tag="KNP54_001604"
     CDS             complement(45902..47404)
                     /locus_tag="KNP54_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBF0892509.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(47495..48685)
                     /locus_tag="KNP54_001605"
     CDS             complement(47495..48685)
                     /locus_tag="KNP54_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0892510.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
BASE COUNT        15812 a         8383 c         5672 g        18843 t
ORIGIN      
        1 tatatagctt ccttacaagc ataattttgt gtatattttc ttattcttta tatcttccat
       61 aaaattcatg tgtagcatat agattcttat ctcctgttat agctatacca aatcccatta
      121 tttcataccc tttatgcaac atgttagttc cttcttctgg atttgtcttc cactcattaa
      181 aaataaagtt tcctatatca tctgcatctc tatttgtata tacaggttta tctggaattt
      241 tatatttaat tatattttca ccttgaactg ctatatatcc aggtttaatc tcactccaat
      301 ctaagtattt caaaaaagta gaatatgaat tttttccatt tatcgtatga gataaagtct
      361 tcttatttgc cattaaatta gaccaatcat ttgctaaacc ctctaatctg cttgctacag
      421 ataacgctct tactccattc tcttttctat actgctttgt aagagcatat actttaccct
      481 ttattctctc tttaaatgct ctatcatttg gattgtaata taaaccttgt tgatttggtg
      541 aagcttgatt tatacattgc ttgataacat tctgatttat gcctcctagt acagtcaatt
      601 tgtctgcacc acttaaaata ctcttgttac tgccattttc aactaaaact acaggagcat
      661 tttttgctat tgtagaggca gccaaagcgt ctgttaattg taagccttta cttagataaa
      721 attctttact atttttataa aactcttgta taactatctt attagtttca aatctatctg
      781 tgccacccaa tctaatagaa tttgtgctct taactaattc gtcgctgatt atttcactag
      841 aaccaagcgc ataactcttt aagcctgtcg tgtcaaatcc cacactattt ccatctgtaa
      901 gtattatagg tactccatct ctagcagcta ctggtgatgc acttatcgca tctgcttctc
      961 ctgtaaatcc attggctata attactttat ctattggctt aatttctttg attttttcag
     1021 ctatttttat acttgtatca aatctatttt caccaaagat tctttgtaca accttctttt
     1081 tggatagtaa ctgattctca acatttttac ttattgttga ttctgagcct attatataca
     1141 cagtctttgc tttgtttaat ctttccatag ttgtgtttgg aatctgattt tgttttgtca
     1201 tcaaaatagg cgcatttaag gctccagcta aaccacttgc acttagacca tctgctaagc
     1261 tattatctga gttgattagt attgctgtat tgtagttttg cttatctgct atttttgctg
     1321 ctgtctcata tctgtcattc ccttttattt gctcaactga tgtcaacgca tttaccatag
     1381 gagtatttac cattactaaa aatagtgtaa gtcctatagc taatatcttt ttactattct
     1441 tcatattatt ttctaccccc aatgtacttt tcatattttt tattagtact catacttatt
     1501 tttaatcaaa agttacaatt ttgttaccat attttatata tgataccata gttatccata
     1561 caactcaaac aatataccta aagtttttat tctctataaa ttcaaaacat tataatttat
     1621 tttatttaat taagttataa gttcaaaata atttatgtta ataagatgtt taatcattat
     1681 aagaagtatc tttttataat aatttttgca atatgaattt ctcaacatta taatcaaaaa
     1741 ataaaataag gtatctcaat ctaattctaa atgagacacc ttatttttat tattttatct
     1801 tgttatttgt atattttata atatctacac tatgtcttac atattaacgc attgtataat
     1861 catatattat ctaaacaaac ttttaatatt aattcctata tcttattagt tcttagtaaa
     1921 taagtttatt ttttctgcta ttttttcaat agcgttttta gctattcctt cacctatttg
     1981 tactaactta gtagcattct taagtcttaa ctcaactact tcttcttgtg atttagaaag
     2041 ttcttctgta gttaatacta ttggagcctt tgaactagct gcaagtggtg ctgctgtaag
     2101 tgcatcaact aattgtccat ttccacctac ataaccatct tttgctacat atgctttagt
     2161 tgcacctgca tagtatttat tgattacttt agcattagta tcttttctat tttctccagc
     2221 taatctttca actttattat ttaaatctat atcaactaat ttgtcttcaa cttcttttga
     2281 tacagaattt tctccaccca ctatttctaa ttcttttcct tttaataatt tttcagcatt
     2341 tgcatctaat tcgttacctg taactattat tggagcacca aattgagcag ctctagctga
     2401 tatactcata gcatcagctt ctccatttcc acctactaca aaagcagtct taaatgtatc
     2461 ttttaattgt tttgctattt ctaaagaagt ttcaaatcta tcttctccag aaactctctc
     2521 aactttactt acacctaatt tagaaagttt ttcttcagtt tcttttgata ctttagattc
     2581 tccacctact atatatattt tcttagaaga tagattactt ccaagtactc ttaatatttc
     2641 agcttctatt tctgatggta gtgaatcttt tttagataat aatattggtg catttttttg
     2701 agaggcaagt ggtgctgatg ctaatccatc aactatagca tcttctccaa ctaaaattat
     2761 agcttctgct tctccatctt tgaatctctc tttactaact tctactgctg ttgtaaatct
     2821 tgaatcacca gataaaactt ctacttttaa ttcttttcca ccttttacat cagttaatac
     2881 tttgtgtaag tctctaacta acttatggtt tttacttgaa acacttattg tttctggctt
     2941 ttcatttgcc ttgcttaaaa ctatatcaaa gcttgatttt tctggtttat ctttatcatc
     3001 actatcttct tgttcttgag taaggattgc ttcattttca aatgttaaag catatccatt
     3061 tttaacttta ttaactattt ctcttcctaa tgtagttaat ctaattccat caaataattc
     3121 ttctgctgat atgtcttgta aatctgcgtt tttaactgtt atcgtatgta attcttttga
     3181 atctatgtca ctataactct tttcataacc ttcaaaagta ccttcttctg atgttatcac
     3241 ttttgagaaa tctaaatgtt ggtctcctac atttaatgta ataacatttg ctgaatcttt
     3301 tgctcttttt acttcaactg tatttgtaga ttttatagtt gctgttaact tgttatcaga
     3361 atcttctgct aaagttgcat tgtaagcatt aactgcatct actatttctt gagcagtttt
     3421 gtagttttca attttatagt caactacttt tccacctaac acttgatgtc ctttatcttg
     3481 aatagtaact tttaaacttt gcccttctgt taaagagttt atcttatttt gtaattgagt
     3541 tgcattagtt aagtttacat tgtctacttt tatatcgtaa actctatcat ttacatttgc
     3601 tcctgctttt gtatcttcaa acttaacttc taatgctttt ctaacctctt cgattagttt
     3661 agcagaatct ttcgcactta ctgtgtaatt tttatcaaca ttttctgtca cagtattgtc
     3721 tgcgaatatt ggtgctgctg cactcataac tgtagcacct gccattacta ttgccatact
     3781 tctctttttg ttgcttaaca tatttatgtc ctccgaatat tattttttat tttttatatt
     3841 cgtatttccc acacataaat aatattatat ataatattat ttttcaatat attttatgtg
     3901 tttacataat ttactaacac aaacactaat aatatcttct tgaacccctt ccccctgctt
     3961 agctctctat aattatgctc aaagatagaa atcctatttt atagtgattt tctactaaac
     4021 aatcatatac taacaaaagt attcaaactc catttttata tactactatg cactaatttt
     4081 tgctttactc ttattactta aatatatatc actaaattaa tatctatctc catatattaa
     4141 aatatataac atattataaa aatcatcata aattagagtt taaaattaaa aattattcta
     4201 atacatgtaa ttgataaaaa ataaaatata agagtagcta ctttaaaata aatgctctta
     4261 tatgattaga tatttttgca taattaaacg ataagaaatc aaatttaatt ttacataaat
     4321 agaatatata tttttatata ataattgaaa ataaaagagg atacctcata atgataaaag
     4381 aatcactttg agataccctc ttacaaacaa ctaaatcaat aattttctat ctttcacact
     4441 cttgatttgc aactgtacaa gaagttttac aagctgattg acaagaagtt tgacactctc
     4501 cacatccacc ttttgcagca ctttgcttta aagtagcttg agataaagtt tttacatgtt
     4561 tattttccat tttcaacgcc tccatttcta attgtttcct attgattata tcataaaact
     4621 actttaatat aaactctatt taaagttgac acccaatacg cctccaatgc ctcctgctgc
     4681 tgatattaac aataacttat aaatcatccc tacttcaaat acaaactttt cttgtgctaa
     4741 aaacacagtc aaaaaaatac atactatgta caaaagtcct actaaaagcc catacataag
     4801 tcctttttct ttcatgtgtt ttgaagtgta aaaccctcct atagctgcag aaatagtagt
     4861 tataaatgat gagaccatag ttatattatc tccaccaata tctgtaaatg tcaaaaataa
     4921 gttatacact aataaaacag ccaaagttat tatatatgca tatcctagac ctttaaaaat
     4981 ataattagat tttcccataa aaaaacctcc tctcaaatta atatatattc gagaaaaggc
     5041 ttttaaatta ctaatttagt cttcttctat ttcttctttt ttagatttaa cagttcctat
     5101 agcccatttt tcaaatggaa ctttagttct atttggtcct aattctaata ttacaacatc
     5161 atcttcaact ttagctacat tagctactat tccacctatt gtaatgacct tgtctcctac
     5221 acttaggcta cttctcattt cttttaattg tttgtctttt ttcttttgag gtctaatcat
     5281 taggaaataa aagattgcga ttactactac ccatagacct atactcataa ttatttgttg
     5341 ctgtggcatt aatttttcac tcctttgtaa attatactct tttgtaaatc ataataaatg
     5401 tttatataac aatttacttt ctctatcttt gagtactatt gaatattata tattaaaatg
     5461 attataatta atagtgcaaa acctatattt catatccata ttttgcaaaa aattcatttc
     5521 taaaatcaag taatctatct tccattatcg cttgtcttat ttgtttcatt aaatttaata
     5581 aaaagtgaag attatgagta gttattaatc ttgcacccag tatttcattt gcttttataa
     5641 ggtgtcttat ataagctctt gaatagtttt tacaagcata acaatcacat tcagggtcaa
     5701 gtggagtaaa gtcttcagca taagttgcat ttctaactac tactttacct tggctagtca
     5761 ttgcagttcc atttctagcg atacgagtag gtaggacaca atcaaacatg tctactcctc
     5821 ttataacacc ttctactaag tcatctggac taccaactcc cattaggtat cttggtttat
     5881 cctttggcat aagtggagtt gtatgctcta acacgtcata cataagtggt tttggttctc
     5941 caacactaag tccaccaata gcatatcctg gtaaatcaat attagttatt tctttcgctg
     6001 attgttccct taagtcttta tacatcccac cttgtattat accaaataaa gcttgcttgt
     6061 cggtattatt atgggcatct ttacatcttt ttaaccatct tgttgttctt tctaaagaat
     6121 tttttacata ttctctatct gatgggtatg gtgcacactc atcaaatgcc atcattatgt
     6181 ctgaacccaa tgcattttgt atttccatag ctttttctgg agttagaaaa tgttttgaac
     6241 catctaagtg tgacctaaat tctacacctt cttcttttat ctttcttaaa ggccctagac
     6301 taaatacctg gaaccctcca ctatctgtaa gtattggttt atcccaattc ataaacttat
     6361 gaagaccacc agctcttttt ataagttcat gacctggtct catatataaa tggtatgtgt
     6421 tactaagtat tatttgtgaa ccaatctctt ttaattcttc tggtgtcata gattttacag
     6481 ttgcttgagt tccaactggc atgaatattg gtgtttcaat aatcccatgt ggagtgtgta
     6541 atcttcctaa ccttgcacca ctctgcttac aagtctttat caattcgtat cttactgcgt
     6601 acataaagtt ctccttaatc atatttattt ctcattattt cttaagatat atttgtaata
     6661 agctattcat ataatttatt gtctaaatag atttatcttc gtcttctttg ttctgttgtt
     6721 ccttaattgc ttcttcatca tgaatactca ttatattaag agcactcttg tcttttgtta
     6781 ctaaaaactt ttttatagca aatagtcctg ctatagctat aactcctatt aaaacatcta
     6841 tcataccttc atttttaggc agtagcaaca tttttctagc aattgcgtaa agtaatgcct
     6901 caataaatgc tcctggtata tgaagagata gcattactac aagttcaaca cctattacta
     6961 aaagtaatat ttgtgctaaa aaatcattaa gctgactgta ttgtactgga ttttgaaaat
     7021 caactatata tgctccccac ataagtctta gaacatctat agttcctaaa aatactgcta
     7081 ttagaactac tactgctaaa acacgttcaa atataaaagc aatctttaat atagggttat
     7141 tctttttttg tttttgtaaa ctatgcatct attacctccc tactttataa tcatagcatc
     7201 tccaaaactg aagaatctat atctttcttt tactgcctca ttatatgcat ttaaaacatt
     7261 atcctttcca caaatagcac ttactaacat tattagtgta gactctggta agtgaaaatt
     7321 agtaataagt ttatctaaaa ctttaaattt ataacctgga tatataaata tttctgtcca
     7381 tccactagtt tctttcatct ttccatcctc attacaagct gattctatag ttctacaact
     7441 agtagtacca acacatatta cattttttcc attttccttt gctctattta ttttgtcagc
     7501 tgcttcttgg ctaaccatat aatattctga atgcatcttg tgatttaaaa catcctctac
     7561 ttttactggt ctaaaagttc ctaagccaac atgtagagtt acaaaggcta tatctacacc
     7621 tttttctttt attttattta acaattcttc tgtaaaatgt aatcctgctg taggtgctgc
     7681 tgctgaacca ttatgctttg aataaacagt ctggtatctt tctttttcat ctagtctagc
     7741 agtgatatat ggaggtagtg gcatatttcc aagttcatcc aatatttctt caaaaattcc
     7801 atcataatgg aattttataa ttcttgaacc ttcatctgat aaatctacaa cttctccaat
     7861 tagctttcca tttccaaaag aaaatttagt ccctactttt gctctttttc ctggttttac
     7921 taaagcctgc caagtatctt cctctgttct ttttaataat aaaaactcta ttttacctcc
     7981 agtttcaagc ttctctccta ttaatctagc tggtataact ctagtattat ttaatactaa
     8041 gcaatctcct ggatttaaat attctattat atctctaaat actttatgtt caatattacc
     8101 tgtctcttta tctaatacca tcaatcttga gctagctcta tcttctatag gaacttgagc
     8161 tataagttcc tgtggtaagt caaatttaaa atcacttgtt ttcaatgtta aacttcctct
     8221 cttaaaattt ctccagctac aataatatca aaaaaacaac ttattttcca caatattacc
     8281 ataatctatc aagaaattgc tatttttaac agacaccata tccacaatat atagatattt
     8341 ttccacgata tacatgcctt atccacaata tatagataca atacacacaa tttttatcgt
     8401 gtttatccac agtatctaca gatataatta ccattttgtg gatatgtttg aatttttagc
     8461 cattttagaa atattttaat ttaatgactc ttttatttta taaatactcg tataatctat
     8521 ttttattttt cattgggata tggaattttt aagtgttcat atgctaatgg catagctact
     8581 cttcctctag gacctctatt tataaatcct aattgaagca aatatggctc atatacatct
     8641 tctattgtat ttctatcttc tccgatagaa gctgccaatg tatctaaacc cactggtcct
     8701 cctctaaatt tttctattat agtcataaga agcttctcat ctacaaaatc gagacccaaa
     8761 ctatcgactc ctaaaagttc cagagcatct tttgccactt tatcagttat ttttccatca
     8821 gctctgactt gtgcaaaatc tctaactctt tttagtaatc tatttgctat ccttggagtc
     8881 cctcttgaac gttttgcaag ttctaatgct ccattagact gtatctctgc atctaagatg
     8941 cttgaagacc taagtactat ttttgaaagt tcatcaactg tataatagtc caatttacaa
     9001 ataacaccaa atctatctct aagtggattt gtaagcatac cagctcttgt agtagctcca
     9061 ataagtgtaa atttaggaag gtcaagtctt atgcttctag cagatggccc tttccctatt
     9121 attatatcta ggcaaaaatc ctccattgct ggatataaaa cttcttcaac acttctattg
     9181 attctatgaa tctcatctat aaataaaaca tcattttcat ttaaattcgt aagtatggct
     9241 gccaaatctc cagctctttc tattgcaggt cctgacgtaa ttcttaaatt tacccccatc
     9301 tcattggcta ttatacttgc tagtgtagtt tttccaagac ctggtggtcc atataaaagc
     9361 acatggtcta actgctcatt tctcgattta gctgcttcta taaatatact aagttgttct
     9421 ttggattttt cttgacccaa ataatcttct aaagtttttg gtcttaaact gttttctata
     9481 tctatatctt ccatcttcat tgtagaagtt attatcctat tttcatcttc aaaaccttgc
     9541 atttataccc ctcctctcgt acttttgaaa atctacttta tatattttca aatttacata
     9601 aactccttaa atattgtttt aaaatccaaa tattataaaa tccaaatact atttcaagga
     9661 tttactcatt atatatgtaa gtgctttctt tataatagct tctgtattca taccatcttt
     9721 tttacatttt tgaactgcct cttttgattc cgacaaagta tagcctaaag ctacaagtgc
     9781 atctacagac tcatcttgtg atatcaaggt aggtttttgt gataataacg ttggttcaaa
     9841 ctctatgtta tttttgtcta ccttatcctt aagctctaag acgattcttt ctgctgtctt
     9901 tttaccaaca ccaggagctt tggataattt tccaatgtct tcacttaaaa tatatgctcc
     9961 taactgtgct ggtgatgcaa atgatagtat tgaaagcgcc accttaggtc ctattttaga
    10021 tacagatgtt agtaattcaa acatcttaag ttcttcccta cttacaaaac cacaaagact
    10081 catatcatct tctcttacaa ttaatttagt atatattttt gtggcttctc ccacttgtaa
    10141 attcattatt gtattggatg atacatttat tttatatcct atcccattat tttcaacaac
    10201 tatactgtct atataaattt cttctactgt accttttata taactataca tacttaccac
    10261 ctatattctt tagagttttt tcaagtttgt ttgaatgagc atggcaaata gccacagcta
    10321 aagcatctgc aacatcatct ggttttggaa ctttttttag acttaaaaat gaagttacca
    10381 tctgttgaac ttgtgcctta tctgctctcc catatccaac tacaccttgt tttacttgaa
    10441 gtggagtgta ttcatataca ggcttcccat tatgagcaca tgcaagcata gtaacacctc
    10501 tagcttgtgc aactgttata gctgttttta cattcttgtt aaagaataat tcttccattc
    10561 caacttcatc tatattgtaa ttctttacta ttgtatcaat tcctttatac acaagttcca
    10621 atcttctcga tatattcata tgggcaggtg ttgtaactgc tccataatcg attgctttaa
    10681 acttgctatt tttgtattca attataccat atccaactat ggctatacct gggtcaatcc
    10741 ccaatattat cattttttaa aattccccct aaaaataaaa gaaataccaa aatgtatttc
    10801 tcataaaaac ttatgttcta aatcattata tcataaataa tattaacaaa tcataaaatg
    10861 ctctatgtaa aatataaaat caaataaaaa agttatatca aagcaagatt ttacctcaat
    10921 ataactttta tatttattac aaataaatta ttgtattttt ataggaatta aatgtgacta
    10981 caattttaat actaatctat ttaatattaa attatttatt attaatttac ttagtattta
    11041 acttaaaata atattaattt actattaact tgcaaagtct tctaatcttg aataggcctc
    11101 ttcttcagta tccataacta cacctttttt gatttcatct tgaactgttt taggaagtga
    11161 atctactctt atttttgttt tttctactaa tgttttactt ccgctatcat catatttata
    11221 tagtgctata tttccattat cattttcaat agtatattta ccttttatag taacatccat
    11281 tgcttgtaca tctttattat cactatattt agattctacc aatatgattt catttttatc
    11341 catactcttt atttttttag ttggatattc ttttttaaaa tatgatacta tttctgactt
    11401 cgtcttatct aataatgact ctggaactat tcctgccatt gtaagtgttc tcttatagtt
    11461 agtttcattt tcgccttcac tttgaagcca aacttcacaa tttttattta atccaaaagc
    11521 ttcttttgac ttttcattca tattcgcact agtacttaca acttcaccag tttgaactcc
    11581 attgtgtttt aatcttgtcc ctatataaac tccgctactt aatacaaata ctccaaccag
    11641 tattaaggca gatattttcc aaggaaataa ttcttttttc ttcttttcaa acattgatta
    11701 cgcctccttt ttctattatt ttctccaagc tgtaagtttt tatacaattt aggtaaattt
    11761 tagaagaaaa tatatttata tttcaaatta ctctaagaat agatattttc taaaaggtag
    11821 ttttctctta atggttatat tcttgtaatt atatggacat aatttataat aaataatcgt
    11881 ttaggaggta ataactttgg aaagaataaa ctgtaatgta attaactgtt cacataacaa
    11941 cagccatata tgttatgcag ataaaatttt tataaatggt gaaaaagctc acaatgacag
    12001 acatacttgt tgtagttcat ttttagatga atctatttat agtaatttat ctagcaacgt
    12061 taataataaa aattgtgagg aattagtttg tactgtaaaa aattgtaaat acaacaaaga
    12121 tggtagctta tgtacacttg ataatatatt ggttgctcct gaaactgata gagtaaacct
    12181 ttatattgaa acatgttgct ctagtttcga atgtaaatag tcatagtata aatataaggg
    12241 tgtcaaatgt aattaaacta acatagtgta gagtatctac aactattagt ttgattatac
    12301 ttgacaccct tatttatttt aaataaaatt tcattattat aaccatgttt ataatgttct
    12361 aactgtaatt aaatttgata aatttctata aattggtata atcaatatgt aaattgaatt
    12421 tagtaaatta atcataaaaa taaaatatcg agtatatagt gttatactaa ctagaaatga
    12481 ggtgcttatg agtacatttt atattcaatt tctttatttt gtaatttata gctttatagg
    12541 atggtgttgt gaaactacat attgttcagt tttacaaaaa caatttgtaa atagaggttt
    12601 tttaaatggt ccattttgcc ctatatatgg atttggagca ttagcaatag ttgctacctt
    12661 gactcctttt gtacacaata ttcctttgtt atttttgttt agtataatta taactagcat
    12721 aatggagtac tgtacgagct ttattttaga aaaaatattt aatatgactt ggtgggatta
    12781 ttctaaacat aaatttaata ttcatggaag agtttgtctg gaaaactcac ttatgtttgg
    12841 tgtattatca ttgattgtaa tgcttatagt acatcctatt gtggttgact ttattaactc
    12901 tatctctaaa aatgtgctat ttatatttgc tatatctata gaaatttatt ttgttttaga
    12961 tttagttatc acagtccata caattttaca attaaatggt aagttaaaac aaatcaatct
    13021 tataattaag gaattaaaag ataagaaaga atactacaaa cttattacac aagaaactat
    13081 agaaaacaaa cttgaatctt tagttgaaaa tagactggat actttggaag ataggtttga
    13141 aatacttaaa gaaaaagaaa attatcgcta tgctaaaaat cgtattgatg agctaaaaaa
    13201 taaacttaat actttgctgt ctaaccacaa attacttcat agacgtataa tcaaagcatt
    13261 ccccaacata agctctaata agcatacaga tattttaaat aaaatcaaag aaaatattaa
    13321 atcaattaaa aaagataaat aataaaataa acacataagt taaataataa aaatactaat
    13381 acataagatt aaggtttaga atattttttg taaaatactc taaaccctaa ttaatatact
    13441 attattttta atcttaattt ataattttag tttattttaa ttttaactca gtaaatttaa
    13501 gcgtttaaac ttcaatacac taatatacta ccccatcaat atctcaactg attctctaag
    13561 tgtgctaatc tctcccacat ttccagggaa aattatatat ggcatattag gaaatttgct
    13621 ttctttgcct gtcatccata ctggtatacc aggttttatc tgtcccatta ctgtagcttt
    13681 ttttactctt agtgctttag taccaacatc actagaagta attccaccct tagctataat
    13741 aaaatttggt cttacattaa gcataccaat tatactggta actgcatctg atatttctac
    13801 agaaatcata agctgtttat ctttatcatt cgtatccaag tcaaaacgct ctcgtctagt
    13861 ataaacagca acagttttac cactgcttat tttttcctct acaactttta taactctttt
    13921 tacctcattt tttagaccat tttcttgaag aactaaatgt tgattaaatt ctataaattc
    13981 tatcggatat ttacaatttt taagttcttc taactgttgg gtagtcttat tcacatgtga
    14041 accaacaagt ataattcctc cattggtatt accttttgat actaattcat ccttagtaag
    14101 tagttccttg tcactcactc cgccaagtac ttttgttatg gcagcagcgc ttctaaacat
    14161 aaattcctta ccaccattta ctgctcgtat aaacgcaatt gtaaatacct ttacatctac
    14221 ataatcggtt gcatttacaa taattttatt gaatccttca gcttttttaa gtttttctgt
    14281 tatagcttca atatttagct ctctaagttc ttttgacgaa atatatatca tatcactaga
    14341 tttgtacttt ccatttgtct tttcttcaca ccactcacct atatcagatg atttatatcc
    14401 aaaagattta tcttttgcaa attcagtcat tcctgctggt acaagtattt ctccttcttt
    14461 aacataatgt acattatcta tagtaaacct accaccttct ttaaaaaatg gcattattat
    14521 ttcaccctga aataacttcc ccgataatct ctctacttcg ctttttaata aattagtttc
    14581 aagaggataa tgtcctctca tagtagaatc actacgactt atgattataa aatccttatt
    14641 aactttcttt gatacatcca caatattctt tgaaatttct ttatgtgctt ttgtagtttg
    14701 agcaacagta aatccccttg aattggtaag tataaaaaac atactatttt tctcattaaa
    14761 gccttgttcc atactatcct tatcccaatc agtataaaca gaaatatcat gaactgtttg
    14821 tacacctgtt gggtcatcat ctaatacaac aatttttcta tctaaatgct taagctcatc
    14881 tgcaagaagt ttatttaatc tatcctcatc tacttgttta aaagtattaa gtatatctat
    14941 gctaattggt tttacttctc tcatttaaaa cgccccttta tgtaatttgt atagtctaaa
    15001 tataatttat atgatataaa caatagtttg ttatttatag acctggaagt ggtataattc
    15061 catttataac actaagcaat aaaaccatta taaatgctac aactccagca atggttcctc
    15121 caattgtcca agagtttaaa gtatctttaa ctgataatcc actaaatctt gaaagtaccc
    15181 agaatccaga atcatttgga agggagaaac caactcctcc agcacatata gcaagcccta
    15241 ctaaaactgg tgacattcca gttgccaaaa ttgtaggtcc taaaattgat gatgttgtta
    15301 ctaaggctac agtagcagaa ccttgagaaa ttctaagcaa ggcacttaat aagaatccaa
    15361 gtactacaac tgatatacta agaccagaca tagtatcaac taagaagtta cctataccac
    15421 ttgcatttat aacactgcca aacgcaccac ctgaccctgt tatcaataat attagccctg
    15481 ctgaatcagc agcttcaata actacatctc ccataggttt atttatgtat ttctttaaaa
    15541 atcctattgc caccaatatt ccaagaagta ttgctatgtt tttatctcct ataaatgcaa
    15601 gtactccact cattgtagaa cctttttcta agaacatact aaatacattt gatataagta
    15661 taagaagtat tgggaacaat aaagaaaaca tagaaattcc aaaacctggt actttagaag
    15721 aatcatcatc ttcaattttt atgctatctt ttccctgctc taaatttttt tctctatcat
    15781 tctcatcaat agcataagct ggatattttt caaaacgttt tccataaatc catccaccta
    15841 taagagctgc tggaaaagca acaattatag aataaagtat aaaactacct acatttgcat
    15901 ttacatttgc tgcaactgcc aaaggtcctg gtgtaggtat tacaagtgca tgacctacta
    15961 tagtcccaac tcctaaggca catacaaaaa ccattagaga tttcttagtt actctcgaaa
    16021 catacttaat tataggcatc attataacaa aagctgcatc cataaaaact ggaattgaaa
    16081 ttaaaaaacc tgctgtagtt actgctaaag cactgttttt ttctccggtc ttagctaaca
    16141 acccctttgc aatagattct gttgctcttg attctgaaag aatatttcca aatattattc
    16201 caagtccaat tacaatacct atactaccta atgtatttcc aaatccagtc gatattgtgg
    16261 ttgatatttc atttataggc attctaacca taaagcctgt aattatagat gttatcagta
    16321 atgccaaaaa cggatttact ttaaatttaa taatcgatac aagtaaaatt cctatagata
    16381 taacaaatgc tatcaaaagt ccatatcctg taatcataat ctttacccct ttatcattct
    16441 actttattat ttatcaattt tatttttctt ttactatgat aacttaacct cgctgtattt
    16501 atataatcta atcctaataa tatgtattta attatattga tatatttaaa tattaattat
    16561 cgtgtttttt tatttcaaca cctgccaact tttcaaaata ctgtgctatt ccactatggt
    16621 catcttccaa atgtccatgt acttttaatg tctgcataat ttctaataat tgacttgtca
    16681 taggtagtgg tacatctaaa ttgtgtgctg tttgcattac attcttaata tctttcaaat
    16741 taatagatat ttttccacct ggtttaaaat cacgattcat aatcattggt atcttcacat
    16801 ccaatattgt actaccagct aggcctcctc ttattgcctt atatactttt tctgggtctg
    16861 cacctgcttt tgctgcaagt acaaatgcct cagaaactgc tgctatcgtc aaattaacta
    16921 ttacttggtt tgtaagtttt gtaacacttc cactaccatt atctccaatt aaaatagatg
    16981 agcttcccat tatattaaaa aatggctcta ctttcttata aatttcttcc ttaccaccag
    17041 ccataaaagc aagtgtacca tcaatcgctt ttggctcccc tccacttact ggtgagtcta
    17101 taaattctaa gcccatatct tttaatttat ttgcacacaa tattgattct gtaggagtaa
    17161 ctgaactcat atcgactact atacttcctt cttttaaagt ttttgccaat ccatccatcc
    17221 caaacaatat atcctgcaca atagttccat ttggaaggat tgtaaataca atatcacatt
    17281 cttgacccat ttctaaaaca cttgcgtatt ttgctccaca tgatataagt tcatccacag
    17341 cagatttatt aatgtcatac accaaaagat tacatccatc ttttaataaa ttttttgcca
    17401 ttggctttcc cattatccct aatccaataa atcccaattt cattttataa ccctccatat
    17461 cttcacattt ttgaaaacgt tttttatgtt ttagagtata ctacatacca gtataccggt
    17521 caatataaaa tataaaagta tttattttaa caataaatag taatttttaa agtcatttat
    17581 tatatttagt catcctatat aagttttaat acatactatt gttttcaaat ataatatact
    17641 acttttacag ttttgtattt taactaattt caattagttt taattaatct gcctttaatg
    17701 ttaatcatgc ttcacacttc aataattttt tatatttttt aatcttatct gcaatttaaa
    17761 ttgcaaaaga ttgaccttat tttcactatg ttgtatgctt aaaattatat aagtttttgt
    17821 atttttatat tgtttagggg ggtattatta agtatggcta catttaaaag attacaagaa
    17881 caagcatatg actacttaaa agaattgata ctatctggag aaatgataga aaatgaaata
    17941 tattctgaaa caaaacttgc tagtgaaata ggtatctcta gaacacctat aagagatgct
    18001 cttcaaagac ttagtcaaga tggatttata gatataatcc caagcaaagg atttagaatc
    18061 catcaaatta cagcaaatga aattgtagag atattccaaa tacgctctgc aatagaagga
    18121 ttttgtactt ttttaattac aagtcaatac aaagaagcta gagcagtaga aactataagt
    18181 aaattaaaac atcttttaga taaacaaaaa gatattttat taggtgataa aaatttaaac
    18241 tcatttgcag aatacgatac attatttcac acaactatag tttcatatgc tcaaaatact
    18301 gaatttgaca aaatgtttaa caattatatg tacagaataa aaaaattagc tctcgattca
    18361 ttgtcacatg aaggaaggct tgaaacaaca ttaaaagagc acacagatat ttttaataat
    18421 attgcaaatg gatgtattga agatatttac agaactactc tcattcatat ggaaactcct
    18481 aaatacatta atttagaaga tttttgtaac aataagttat tttagtatta tactttcatt
    18541 tattaaaaat atatctatct caaattaatt tcctaattta taaaaaatat tctataatta
    18601 tattgtaact aatacttatt ctaaggagtg atttttttga acgaagatgt tgtaactaat
    18661 gaaactattg acaaagatta tgctattgaa gaagttcgta tggcatgcaa acattttggt
    18721 gatttatatt tttatttttc caaagtgtta tttgaagagt ttggtgaaga taaaactagc
    18781 gaaatattaa gaaaagtttt atttgaaagg tctgaagaaa gagctattgc tatgagagag
    18841 agagctcatg aaaatggaga tgaattaatc gcagacaata ttattagcac aactgatgtt
    18901 ccatttctag gatgggttcc tgaatttgaa gagttacatt gcccctatgg agcttcttgg
    18961 cttttaagat ttgaggaaaa tccttggttt aaaaaatttg cttctcttta ctgtgatgtt
    19021 acagatacta ctgtagctga agtatttaca ggagatacgt cccataaaat aacaaaaaac
    19081 attctatggg gagataaaag ttgtgaaaga atatatttcc atgatgacaa ggtatctgaa
    19141 ggtaaatata cttatggaaa taaaaactgt aaataaatga tttaaatttt ctatattcat
    19201 atactatatt ttgtactttt tcatataaat attataacta gtcttttatt ttacttttgt
    19261 ttaacctaaa gataatttac ttttaatcta tatgaattat catataaata atcagaaagt
    19321 tatctttata aattatagtt ttagatttat aatttataaa atatttatgt tctttgtaaa
    19381 attttttaga agcttctaat gttatgctat aaaactatct tgagaagggc tgattgaatg
    19441 tttaataaaa tatatgaaaa gaaagaattt atagtttttc aagttaaaaa aggttatgta
    19501 gtttataata ctagaaagag ttttgaagaa ggtcatacac atttaaagca ttttgaagca
    19561 gcaaagacag ctattgattt agcaataaat aaaaagattc ctagaagcaa agatggatat
    19621 tatctgacta gtttaattcg cataagtgat gatggttatt acattgataa gttaagcgaa
    19681 ttgttatatg ttagagaaca aaaaggtaaa aaagaaaagt actgtaattc tggttatcag
    19741 atgtaacaag actagttgtg aattataagt accaatcata agtaccttta gtcttaaaat
    19801 caaagagtat cagtaaatct ataaaaaaac aacttactga tactcttttt aattatatga
    19861 ttaatatttg aatttgatac aaaattttat acaaaagttt atgttatcta ttctgattct
    19921 ttgtctgcaa attggctatt ataaagcttc tcataaaatc cacccttttc cattaattca
    19981 tcatgattcc cctgctctat aatacttcca ttattcataa ctaaaatcaa gtcagcattg
    20041 cgaattgtag aaagtctatg tgctataaca aaactagttc taccattcat aagatttctc
    20101 attgcttttt gaagcataag ttccagccta gtatcaacag aactcgtagc ttcatcaagt
    20161 atcaatattg aagggtctga tataaaagct ctagctatgg ttaaaagctg tttttcccct
    20221 agagatatat tagatgcttc ttcatttaaa aacatattgt atccatctgg aagagtggtt
    20281 ataaagtgat gaacatttgc tacttttgct gcttgtataa tttcttcttt agtagcccca
    20341 aatctaccat attctatatt ttcaaaaatg gttccattaa ataaccatgt atcttgaagc
    20401 accataccaa acattgaacg caaatcttta cgtttcatat ctcttatatc tactccatca
    20461 attttaatag cacctttctt tacatcataa aacctcatca ataagtttat taatgttgtt
    20521 ttacctgctc cagtaggtcc aacaatagct accatctgac cactttttac ttctgcattt
    20581 aaatcttcta ttaaagttga attttctcca tatccaaaat taacatgctc aaatgtaaca
    20641 tttcctttta cattttctat cttaactgga ttttcaacat caggtatttc ctcttcttcg
    20701 tctaaaattt caaatacacg ttctatagct gcaaaagaag attgtattac tgtagataac
    20761 tgagtcattt gtgaaagtgg ctgatttatc tgccatatat aacgcacaaa tgcttgtaaa
    20821 tttcctactg ttattcctcc acttactgca tatatagaac cgacaactgc cacagctgca
    20881 attccaaagt aagttactaa tgaaaccata ggattcatca tacttgatat aaattgtgcc
    20941 ttaaatccat tttcacaaag ttcttgattt acttttttaa attcttttat agaatcttct
    21001 tctttaccat atagttttat ttcattaaat ccagtataca tttcttgtac ttttccattt
    21061 aattttccaa gagcattttg ttgcaatgaa aatctacttt gagatttttt tactacaaat
    21121 ttagatacaa aataactaat tggaattata aaaagagcta taagagccat atatatatta
    21181 attgtaaaca tcattgaaag tgccaaaatt atgactaaga ttgagtttac aatttgcata
    21241 aaactctgct gcaatgcatt tgatattgta tctacatcat ttgatatacg acttaataca
    21301 tctccaaaac tattactatc aaaataacta ataggcaatc ttcttatttt attttcgact
    21361 tcatttctta aatctctcat tgtgttttga atagcattcg taagtagaaa acttgaagta
    21421 tacgtaaaaa ttgcattggc aaaatatata catgctaaaa tcaccaatat ttttgttaca
    21481 taatcaaaat ttacggaagc ccctggtact ccttttgcga tactaattac atctttagtc
    21541 aattgtgtta ttatcaatcc ttcagtttta ggtgcaagtg cattcatagt agctgctgaa
    21601 attatacata taatagctat aataaaggaa aatttatatt tctttacaaa tggaagaagt
    21661 ctaccaattg ttttcttaaa acctttagac tttttcatta ttctaattcc tcctttttta
    21721 actgagatgt tgcaatttca tagtatattt cacagttttt taataattct ttatgagttc
    21781 ccattcctac aacttgtcct tcattgagta ctataatctt atcagcatca ataatagaac
    21841 taattctctg ggcaacaatc aatacaattg catcttttgt ttccttcttc aatttagcac
    21901 gaagtattgc atcagtttta aagtcaagtg cagaaaaact atcatcaaaa atgtatattt
    21961 caggtcttct tataatagcc cttgcaatag aaagtctttg tttttgacct cctgatacat
    22021 ttgctccacc ttcactaatc aattcatcaa actttctagg tttttttgat ataaactcat
    22081 atgcttgtgc aacttttgcg gaatattcta attctgactc tcctgcctta tgtttcccaa
    22141 atctaatatt atttgctatg ctaccagtaa aaagcagtga tttttgaggt atgaatccta
    22201 tcttttttct taaagctttt aaatcatatt ctcttatatc tactccattt atcttaatgc
    22261 taccttctgt tacatcataa aatctaggta tcaagttaat tagagtactt ttcccactac
    22321 cagtacttcc tataaaagcg actgtttcac ctgtttttgc agtaaatgaa atatccttaa
    22381 gtacagaagc ttctccatct ggataggtaa aagttacatt atcaaattct atgataccct
    22441 tattttcagt atccttaatt ccattttcag gattttttat caatggttct tcatttaata
    22501 gttcttttat tctatttgca gatacctctg ctcttggata cataataaat accattgaaa
    22561 aaagcataat tgaaaacatg gcatggaaaa gatattccaa aaatgcaacc aactgtccaa
    22621 cttgaagctc tccaatattt atcttctcac ttgaaatcca aaatacagcc aaaacagcta
    22681 tatttaatag taaaaagaat gctggttgag taattgacat aagcttaaat agtttcttag
    22741 aaacattagc ataatatgta tttgtttttt caaatcgctc tgtttcataa tcatcatttc
    22801 caaaagctct aattactctt attccagtta aattttctct cgatataagg tttaatttat
    22861 ctagtccttt ttgttgtttt gaagatattg cctgagatac ttttgctatt attgctactc
    22921 caataattat aaaaggtact gatatagcca atactataga aagttccaca cttgttctaa
    22981 ttgtcattat tatacttata atgaacataa ctggagttaa taaggcagtc cttagtagta
    23041 tattaacaaa ttgttgaatt tgaaatgcat cattcgttgt tcttgtaatc attgaagaaa
    23101 ttccaaattt attgtattca gtatgtgaaa attcttgtga tttctcaaat atgtcatttc
    23161 ttatatctct ggttacactt gttgatacct tagcagaaca ataacccaac aatatactac
    23221 ctacaacccc tataatagaa ataataacaa tcactattcc catttgtttt atgtaagcta
    23281 tattctgatt tgcaatacca ttgtcaatta ttttagctat tatagttgga atccccaact
    23341 cgactaatgc aaaactaaat atagccagta tgtttaatac tattaataac ttataattct
    23401 ttaaataact taaaattaat ttcatatttt tctcctttct taatttttga gatagtgtaa
    23461 tcatgtaata atactaaatt tataaatgct taattttata aaaaaaggag aaaagagtta
    23521 acgcactctc ttctccagca tattcttttt aatacaccct ccgacaagtc gcttatatgt
    23581 taacatattt gacaagtaat gtcaattcat atagccaaaa gtcttttaaa tgcttcgttt
    23641 cataacattg taacaaattg gcatgtaatt tatttttgtt ttttactgta ttccaatttt
    23701 acaagttctc caatattact agctttctta aaattcaaat tagtcttatc tataccagac
    23761 ttaaatagtg aaatccctct ccccaatatt attgtcaata tatatatata ataatcatca
    23821 attaagttat ctttcataaa taattttact atatcgcctc caccaactat ccaaatatct
    23881 tttttatcct tctcttttcc aatttgctca attaattttt taggttctaa attaatttat
    23941 agtgagatta ttctatgtaa acatcacttt tttactcatt caataatacc ctattaataa
    24001 atcctcaaac taatttaaat aaactttgta taaaattaaa aatatattat ataaataatt
    24061 taaaactaca ctaacttatt gaaaattcta attattacaa ataaatattg ctctctgtta
    24121 acgctagttc tataatataa ttataagcta ttaatattat aaagccgata ttactaatat
    24181 aataattata atacttatag ttaatttact tttgttgaaa ggtggtaaat aacatgaaaa
    24241 tttcagaagt cgctactcca aattttttgc tagatttaga ccagttagaa aagaatatag
    24301 ataaaattca acaaatttgt acaaataata ataaacaact ttggcctatg cttaagacac
    24361 ataaaagtac ttacatagcg agacttcaaa aaaatgcagg tgctagtggt tttctagttg
    24421 gaacacttga tgaaggtgaa gctctgataa aagcaggttt tgaagatatt atgttggctt
    24481 atccttacat gggagaagta aatataaata gaattgtgac tatggcatca aaaataaatt
    24541 taatctgtgc tacagataat atagaatgtg ctaaggctta tagtgaagct ttttctaaat
    24601 caaaaataga gtgcaagcta cttattattg tagattgtgg cttacaccgt tttggggttg
    24661 aaccagaaaa agtggttgaa cttgctactg aaatttctaa gctagaaaac atcaagattg
    24721 ttggtataag ttcgcatcca ggtcaagtgt atggttgtag ttctccagaa ggtgttccag
    24781 atgtttgtgt tcaagaagat tcttctatgg agaaagcata caaagctcta actgataatg
    24841 gatttaatat agaaattgtc gcttctggta gtactccaac agttgaatct gaagctgctt
    24901 ctaaaactat aactgctgta agacctggaa actatgtata ctatgatgct atacagatag
    24961 gtttaggttg tgctactgaa gatatgtgtg ctcttactgt tgtgtgcact gtaatctcaa
    25021 aaaatagcag tggatactat ttaattgatt gtggaagtaa gtgccttgga cttgataaag
    25081 gtgcacatgg aaatagtagt attgttggtt atggtagggt atgtggacat ccagaactta
    25141 ctattgattc actttcagaa gaagttggaa aaattaaagt aaatggtgaa actgatataa
    25201 aaattggtga tagaataaga attataccta atcattcttg ttccactgca aacttgacaa
    25261 gtaatttatt aggttttaga ggagatacaa tagaaaaagt catagaagta gatattcgtg
    25321 aaaattcaaa acaaatcatc ctttaaaaac acatttattc tgatattaac atgaaagtat
    25381 atttttctta aaattattgc taataactaa tgttaatgtt ggataaataa aaaacataaa
    25441 ttctagaaat ataaatttaa aagaagaggc tgtctcaaaa tagagataag cctctctttc
    25501 attgttgaaa ttatgaaaat atacttgatt tcatacaaaa agagtatctc atgaactaaa
    25561 aagttcactt tgagatactc tcttttttta attaatatac acattaatta ctatcttagt
    25621 ttattactat atatcaatta ctactcatta atccttgtat atattaattc ttatatatca
    25681 tttatagtta ggttataatt ttatgttatt tacattaatc ccataacagt gagtaaaact
    25741 cttactatca acatccccac tattgcatca aatataggaa ctgccaacag taacattcta
    25801 tacttagtac tggcatttgc tacaagcact attctggcat aatgaccaac tagagtaccc
    25861 attaacatac atggcataat taatatggtt gcttgtggtg cagtgattag accttgtgca
    25921 aataagtttg cagctgtagc tgctcctgct gccttagcaa agaatgctgc tatcaaaact
    25981 acaacagatt ccccaggtag tccaaaaata cccattactg gtccaaaaat atttcctaaa
    26041 atatcaacta aaccagttaa ttgtaaaaac tgcactatta cataacccat tatcatggct
    26101 ggtaatatct gttcaacacc tatgtaaaaa cctttttttg ctccccccat aaatatctca
    26161 acagcagttt tcttaggttt actatttaca attacatttc cagtattttg ttgactcata
    26221 ctacacagcc tccttagcct tattcttttt atttcttaca cctatgatta atctaactag
    26281 attagcacca agtattttac agaatatctc tataagtatt attggaccta atgccaataa
    26341 tgctattggt aaaagtggag cttgagtatt tattgtgttc agtataacag ctgaaccagc
    26401 atattgatat gctacaaata tagttctttc atcatctgtt atttccccac tttcaaataa
    26461 ttctttcgtc attattgagg ctacatctga actagtaaat gaagatacaa atgctattcc
    26521 tgctattcca ggtataccaa gcagaggtct aagcaatgga ttaaatatct ttgatgccgc
    26581 tttcattcct cccatagatt caactacatc tataagacct acagcaaaac agacagttgg
    26641 aatcaaagtc agagcaaata agaaaccatc ttttgctccc gttcctcctt tacccataaa
    26701 gtctacacca tctgcaatag taccaaatga acctgtcaga ttagcaaaat ctaatgcttt
    26761 aaggaagcct tgactatctt taaacactcc tgaaaataat actatcaata caaataaaga
    26821 taaataccct ttccatgtta ccttattatc tccagctgtt acatccatat aaaatccccc
    26881 tttatacctc aaatttatct aagtttaaaa taactgtaga aattaatttc accctctcaa
    26941 acatagaatc tactactgca tattctcttg atgtgtggtt ccattctcct cttacaccaa
    27001 atgaacagat tgtaggaacg tttgcaatag ttaaataact tgcatctgaa ctacctccaa
    27061 gtctcttagc atttaattct ccaaatccat tttcttttga cacttcattt acaaatgtat
    27121 gaaatctcat aacatcttct gtagtttcaa atggcatcat ttcacttata aaattaactt
    27181 ctgtagaagt tccttctatg taagtttctt tacatatctc tctaacttgt tctttaacat
    27241 tctccatttc ttctactttt tcaaatctaa ggtctacttt tatactacaa tcttctggaa
    27301 tagaattttc cactcttcca cccttaatca cacttacact tactgtagtt ccaacatcta
    27361 aattagtcaa tttttgtatg cgtagtatct tattagccat ttcttctata gcatttcttc
    27421 caccttcaaa atcattacct gcgtgtgttt ctacaccttt tacatgtata ttacatccta
    27481 ttcttccttt tctacctaca cacaaactat tatctactaa tccagtttcc atattaaaag
    27541 cacaaagacc accttttgct tccctcaata taacatctgc acctgttgaa tccttatgtc
    27601 ctatctcttc atctccagaa aatactattt ttattggtct ttctttgtat cctattttat
    27661 ttaatgcttt aatagcatat aaggaaatta ttataccacc cttcatatct aaaacacctg
    27721 ggccatatgc ttttccttct attattttaa atggattctc tccaaatgta cctgtttcaa
    27781 agacagtatc catgtgacct gaaaaaatta ttggcttttt atctatattg gaaccaagtg
    27841 tacctatcaa tgtactacca ttatctccaa catctactaa ctcgcaatct aaaccttctt
    27901 tttcaaactc aaactttaat ctcttagcca atttatttac gctttcttta caatgtgtat
    27961 agctttccat attaacaatc tctttccata atgaaactat ttcttctcta ttctcatcaa
    28021 caaacttaga aatttcattt aaatatgtat tcataatctt ctcctttatt ttcaaataaa
    28081 atgtatttct ttcctaaaat ctaagtttat tttaggaaat cttaaaagac tagtccttaa
    28141 ttacaaaata gcacaattat tcttgacagt caacatattt ttcagtcttt tttatatttt
    28201 ctgatttttc tttcaatttt ccttttgtaa aataaattga cgcgttttat ctactattat
    28261 aaaatgaggt tataaattga ttgattagtt acaatactct cgaaatttta aaggaggttt
    28321 tatgaaatat aaaattggtt ttttgacaac atcttatttt atgtcagata agtttaaaca
    28381 agctcttaaa gaattaaatg atacttgtga aattacattt attgagctta aaggggagaa
    28441 tccttttaat aatttaccta atatatacta tgagcaagta gataattttg atggatttgt
    28501 atgcagtggt atagttccat atagtgaact tataataaat ataaaagaca taaaagttcc
    28561 attaaatttt ttaaagcttg atgaaaaaga tttttataaa tacttattca aattattaaa
    28621 tagccaaaaa gatattgact ttacaaaatc atttatggat tttttaagag aggacaacaa
    28681 ttattatgat atatattcat taatagactc taataaatgt ccatatacaa ttaaagattt
    28741 taatatccct caacctgtat atgactttaa aaaattaaat gataaattat tggaaataca
    28801 tttagactta ttgcgagata ataagattaa cctttctttt actagaaatt acatcattag
    28861 ttgtgaactt aataaacttg gatatgattc tatttacatg gttccatcta cagaatcaat
    28921 cctgaataca tttaaatctc tggtgaatga aataacatta caaaacttag acaaaaataa
    28981 atctgcaact tgtatagtta cagtaaatag ttcagagtac ataaatgaag atttgatatt
    29041 taaaaatgat gagatacaaa atcaaatata taacactata ttaaattctc tatcaagaca
    29101 tggattctat ggagttcagg tcaaaaaaaa tgatatgaaa atagagatac acactactaa
    29161 agaaatgtta aacaatatga ccaataacta tacagatttt tttatttcag aagatttaaa
    29221 agaaattaaa tatagcttaa atataggttg gggcattgga aatacaaata ttcatgcaga
    29281 gcaaaatgct cgtcaagcta atggtaaatc tgcttctttg aatggaaact gtacttttat
    29341 agtaaatgat actaatgata caataggccc tttatattca aataaaaatt ctaataatat
    29401 tgaagatagc tcaatagcca ataaagttgc ttcttttata cctctatcta atacaaatgt
    29461 atctaaaatc atgtgtatga ttaatgatag aaattcaaat aatgtgtcag cagaaatatt
    29521 agcagactat atgaacataa ctcttagaag tgctaataga atattgagta tcttatataa
    29581 agcaggaatt gcaactattg taaatacaaa actcgataat caaagaggaa ggccaaaaaa
    29641 aatatataaa gttgatttct tatcttttct aaataagatg cagaaattaa attcttaata
    29701 tttaattttt taataaaagc aatgtatttt ctctaatttt aaagaatcaa aatgtttaaa
    29761 ttttattaga atatacaact ttttacttta aaatacctaa accttttatc agtgaaataa
    29821 accataatat atcgtaactt attagaaaaa caaaataatt tcatatacaa ataataaaat
    29881 agccactaca atccataatt tgcagtggct actttttaca ctatcactta ttacttattt
    29941 ttaaaaatta attgtatttt ttaaataatt tatacacacc tattatcagt aaagcaataa
    30001 atacaagtat atctataaaa ataattattg taacatgtct gacaatattg taaataaaaa
    30061 atatagagaa tatttctata gacaacgcta caaaacacat aaaattcgtt aaataatctg
    30121 caatagtatc actataaaaa gcatgtattt gtaaccatct ccatataaat ggacgtaaaa
    30181 gtattctgaa tacaacacaa atgacagggt aggcataaat aaatttttta tctacataat
    30241 tagctacacc attattccat tggataggaa tttgaggtgg caacttttga aatactgtta
    30301 ttgcaattta aacactacct ctctattcta ttaatttata actataatat agtcttaaat
    30361 attttcactc tataaaattg tatatttagt atatcttaaa atcaaactaa ttatctttta
    30421 taagttttca tacaataata tctcctttca ataatatatc tttttttata tttaaaacta
    30481 tcttattttc tataaaataa tgtataaaca aggtttacag tcaagtattt ttattatttt
    30541 tttgatttca taaaaaaagc atagcaaatt atttgctata cttttttact aaattattta
    30601 ttctatatct tatatgaact tattgtttaa ctactacaca atactagctt taatcatcat
    30661 attttttgca aacatactgg cttcatatat ttcttgttca tctggatgac tttgagattc
    30721 ctcatggtta tttaattgtt ggcgaatatg ttcgttgtca ggagaaagtt ttaacatctc
    30781 tttatatttt gctttcaatc cttctgctat cttaccttga catatgaatg aacctagtat
    30841 ttcattatct tttgggataa ttgattctat cttttctatt atactagctc cataacttcc
    30901 ttttttactt gctcccattg ttccaaatag tgctatcttt ttattgtgaa tattttcaag
    30961 cacttgtttt gaatttttat cacaaattcc cttgtccacc caatagccta agaatactat
    31021 atcataattt tcatagtcaa taccataatc aactaattca tttacatctt taatgtcttt
    31081 ttcttcttga atttcatcat atatagtata agcaatcttt ttagtatttc cagttaaact
    31141 tgaatataaa actaaacttt tcatgatgtc tcctcctctt tatctaaata tttatctaaa
    31201 tcaccaaaaa tatattaacc ttaacaaatt atttattttt ataaggatat tctaatctag
    31261 tatacatcca aactgagagc gtgtttgtaa agcatctgca cacttcttat tacaataaca
    31321 gcacttttta atctcatcta ctcttccatc ttttactttc tgtaaccaat tactatctgc
    31381 tagtaattgt cttgacatag aaaccatatc tactctatta tttgaaataa tactttctat
    31441 aaaatctggg ctagacaatt ttccaacccc acatactgga agatttgtgt gtttctttac
    31501 ttcatcagct aaatataaaa aacagccttc ttctttaaag taaggatgat tattggttgg
    31561 tatagtatct tctaattttg aatgatttgc aagtgttaca tgaaaactgt ttacacctag
    31621 ggattcaaat tttttaacaa aatactcaac ttccgaaagt aaaactcctg catttccata
    31681 atgaggattt tcttgtctta ttgcaaattt atagtctatt ggaatgtcct taacttcatc
    31741 tcggatacta ctaattattt cgcttgcaaa tctacttcta ttatcacacg ttctaccata
    31801 ttcatcattt ctattattaa atatacttga tgaaaaactt cctacaagcc tatcaccatg
    31861 aatttgaatc atgtcaaaac ctgctttttt tgcattcaat gctgttactt taaataaatt
    31921 tataatattt ttaatttctt ctttgggcat atttgttatg taatctttta ctccgtcatt
    31981 cattattttt tttatctcat catgtgaagt aattcccata ttcatagtat ctttaattaa
    32041 attaacatca taatctgaac aaaatagttg tgctgatacc tttgcaccag aattgtgtat
    32101 ttcatctaca attttcttgt atttcatgac tccatcttca tccgataggc ttatagctac
    32161 cttatgaaaa ctaggtctaa tagatacatc tcctagagta atcagagcta ctcctgactt
    32221 agcaatatca gaaaactttt taattttttc ttccaattta agacccatgc ttgtaggtgc
    32281 aaaagatact ctatttttta attccaaatt tccaatttta attggtttta ataaattaca
    32341 atacatccta ttcttcctcc acagctgttt ttatatcctt taccacatgt aaattcttta
    32401 ccagttcttt atattctgta tccgagaact ctttttttat gtgattatcc cactttgaaa
    32461 atatgttttt tatatcccct aatacttcct cacccttatc tgttactctc aactgaaaag
    32521 ctctactatc attagggttt tggatttttt ctatgtatcc atcttgttct aacctagata
    32581 tagttcttgt tgtatgagct ttatcaactt caaattctgt agaaacatca ttcaaagaac
    32641 aattcctatt tttattaata taaattaaat agaaatatag accattcgta agtttatatg
    32701 gttttaaaca tttttcacaa taaagtttaa agtttttttg caagttacaa ataatatatg
    32761 acaaactttc atactgtaaa tttttaaaat ccatcttaaa tttcccttct ataattataa
    32821 tatgtttgac tatatcaact atattatatt aaacaattaa tatagtcaag aatattttat
    32881 tctctaaatc tatgttttat taattcttta aaaaactatt atataaaata atcatgataa
    32941 aattagaaat tggaattttt aatatgtact gtacataaat atattttata taaaagttta
    33001 tattttcaaa caagtaattt ttcgaaaatt gtctaaattc agtaaaaata tggtaatata
    33061 tacataagca atataaatct ataaaaagga gtgttacata tgatatctaa taaaatgcaa
    33121 actttagttg caaatagttc tgttataaga gctatgtttg aagaaggaaa gaaactttct
    33181 gatatttatg gtgaggaaaa tgtttttgat tttagtatag gaaatccaag tgttgaacct
    33241 ccagagacta ttaaagcagt tataaatgat attttaaatg aagaatctcc aaatttagtt
    33301 catggatata tgaacaactc aggatatgag gatgtaagag atgctattgc tgaacacata
    33361 aataaaaaag atggattaaa tcttacaaga gaaaatttaa ttatgacttg tggtgctgct
    33421 ggtggtctaa atattatttt aaaaactctt ttaaatcctg gtgatgaagt tattgctttt
    33481 gcaccgtatt ttggtgagta taaaaattat acagaaaact atgatggaaa attaatagaa
    33541 gttcctacaa atatagagac ttttgaacca gatttagatg ctctaaaaaa tgctattact
    33601 ccaaaaacaa gagctttaat aataaacact ccaaataatc ctactggtgt catatattct
    33661 gaagaattat taaaaaatct tggagaatta ttggattcaa aacaaaaaga atttaataca
    33721 agcatatacc taatttctga tgagccatat agagaaataa tttatgatgg tgccaaagtt
    33781 ccttgtgtac taaaatacta tagaaattca tttataggat actcttatag taaatcatta
    33841 tctctacctg gtgaacgtat aggatatatt gttgctaatg ggcaaatgga tgattttgat
    33901 gatgttatgt cttcattaaa tgttgcaaat agaatacttg gatttgtaaa tgctccttct
    33961 ctttttcaaa gggttattgc aagaagttta gatgcagaag ttgatgtaaa tatttataaa
    34021 aagaattttg accttctata taatagttta atcgatatgg gatattcttg tgttaaacct
    34081 aatggtacat tctatttgtt cccaaaagct ccaattgaag atgataaaaa attctgcaat
    34141 gatgcaaaac aatttaattt attattagta ccaggttctt cttttggttg tccaggtcat
    34201 tttagagtat catattgtgt atcttatgat aaagttaaaa gttctttacc agcatttgaa
    34261 aaattagcca aattatataa tttaaaataa ctaaatcaaa gtaattcaaa taattaacta
    34321 ccttagtata gaatacttac attctatatt aaggtagttt ataattttat gtactatatt
    34381 ttatacatac catattattc caatatgctt gaatattctt atctatagta ctaatataaa
    34441 ttacaaggag gtgtttgact tgaaaaaagg ttatgtttat ataatactga ctaccttatt
    34501 ttttagttca atggaaatta gtctaaaaac tgtcactaat gactttaatc ccttacaaat
    34561 aactttatca agattttttg ttggcggttt agtcttacta ccttttgctg taaaaagatt
    34621 aagagctctt agtctttcta ttacaaaatc agacttaaaa tactttgcat ttttaggttt
    34681 tatgtgtgta gtagtaagta tgtcattgta tcaacttgct gttctaaaca caaaggcatc
    34741 tgtagttgct gttttgttca gttgtaatcc agtctttgta atgcttttag cttacttaat
    34801 tttgaaggaa aaaatatata ggcacaatgt aatttcactt atattagaag ttcttggaat
    34861 tatagttata ataaatccat tgcatacaaa actaactctt agtggaatat tcttaacatt
    34921 atcttctgct attatttttt caatgtatac tgtatttggt aaaagaaaaa ccttaaaatt
    34981 tggtggaata gttgtaacct gctttagctt tatatttggt agtttggaaa tgttgatatt
    35041 ggttttactc actaaaatta attttatcgc agatatatta aataaaaata agcttcatgt
    35101 atttgcaaat atccctattt ttagtggata taccttacac aatatgccca ttatgattta
    35161 tgtattcgta tttgttacag gtgttggtta tgcgctttac tttatggcaa tggaagctac
    35221 atctactagt cttacatctt tagtattctt ctttaaacca gtaatatctc caatactagc
    35281 attattaata cttaaagaaa ttatccctat aaacatggtt ataggaattt tattgatagt
    35341 aattggttca ataatttcta ttatacctac gataattact caaatgcata ataaacacgt
    35401 tgaagccttg tataaggagt agtaattgat aatctatcat agttatacat aagacaaaat
    35461 ttattagatt taaacgcaat ataaaagaga tgctattata atagcatctc tttatttata
    35521 tttattttaa atttattaaa actctattta gctaaatttt gcaaaaagct ataagtttgt
    35581 ggacaagctg attttaactt actatttgta tcttgattta aatagtaata tgcaaatgat
    35641 tctgcaaaaa attcttctgg atatacacct aagtagttta cattacctaa agaacgacct
    35701 tctttagcaa atatttgttt gaattgtgct gatttagata tatcatttaa tactatatgg
    35761 tctattgcat gtgctgtttc atgtaattct aaatttattg catcatgccc tttacctttg
    35821 ttactaaatc ctattctaag agctactgta cttccaccta aacctggaac atcatcccaa
    35881 gtttttccag taccttccca tcccttagga actacacctt ttaaataagc atattctttt
    35941 tcatctgtta actttccact taataatttt atttttaagt tattttgctt taatgcattt
    36001 aaatactttc catctatatt agctaatcta tttaccatag cattagcttc gtttttatcg
    36061 taatttccag ttggaaaaac tactatttga ctaagtgtgt ctttattttg ttgtatagta
    36121 gtactatctg catgtgcact tactggaact gaacttatta agaatattga tattatagct
    36181 attaataatt ttttacttgg tctcatatta ttccctcctt tgagttaggc cgggagtaat
    36241 aaatttcaaa ataaaaaaga tacccaagag tatctttgta tatacaaaaa gaaattttta
    36301 ctcttttcgg caactggctg gcatggttta ctaaacttta gcccctatag ctttgcgtga
    36361 ctaggtttcc ctagttttgc ctcatttaat tttatatcta tattatagct tatatctttt
    36421 taattgtcta tatccctttg gaactttttt ctaaaaagtt attatttttt tacataaatc
    36481 ttcaaaaaaa aatatcttct aacaatattt tcattattaa atattgtttt agaagatatt
    36541 ttttaatata acttatattt tttataatgt tagggtctaa tttgtatttt tatttcttct
    36601 taatacgata agtcctacaa tagctcctat aaccaaaagt atttctccaa taattgtagt
    36661 actatcccct gtttttggtg gtactggtgg atttaccaaa gtatcatctt taactttatt
    36721 atttttttct tctgacactg atggctttac tacttctggt attggaataa tctgtttaac
    36781 aggagtttct atcatctctt ctgatggtgg tactggcgga ttcaatacct ctggtattgg
    36841 cggatttatt atatcttctg atggtggtat tggtggattt ataactatag tatcctctgt
    36901 atcagatgaa cttgatggtt tccttggttt atctgtgctt ggtggtactg gtggatttac
    36961 tattggttca tctgtatttg gtggtgctgg tggatttact ggtggatttt cttgtcttat
    37021 gttttctata tttccaatat ccactattct accaatatct ttattaccaa tttcaacctt
    37081 aattttatcc ttcagttttt catatccact tggagccatt atctccacta aataatatgt
    37141 tcctggtttt tttatactag attgaattat accatcttca tcactaacta aatccttaac
    37201 tactatattt ccaaatgcat cttctaaatt gaacttagca cctgaaagta catttttatc
    37261 taaagcatcc acttttttag cttcaaaagc ataaccttgc ttagtagtct ctactcctgg
    37321 aggacttgaa ccattaatct gagccacatt tcgtatagtc tccccaactt ttacatttgt
    37381 gaagtctgca tcaaatgtaa cccaactttg cacaggttcc ccttctttta tctgtttaaa
    37441 ttcgtattta tttactaatc ttattgtatt ttttccatct ccagcttctt ttttaagttc
    37501 aagattatca gaatatttta tattagatat ttctagagct gagtttactt catctaaaag
    37561 atttacttgt cctgcatcat aaaccccata agttgacata ttgattttgt atttaacaat
    37621 ctggttatca ctactattta aaactttttt atcaacttct ttttttgcgc ttattaatcc
    37681 agaatttttc ttaaagttta tctcatcatt tttatcaatt tcactattat ttgcatcaag
    37741 aacagctcta tttatatagc tatcttcaat actaattacc tttaatgtat aagctataaa
    37801 aaactttgat tccacttctt ctttactgag attaattgta aatccagtta taactttatc
    37861 tacttgccca ctttcatttc ttttttcttc tactttatat gaaatattat tggcaatttt
    37921 ttctttactc caaggagtcc agctcccatt cattggaatt tctacaactc taaaatcatg
    37981 cccagcttct cctgaagtag ttaatctcat gccttctggt atattatctg ttataacaac
    38041 attacttatt ggtgatttat catcatttat tgaaatctga tagtttatta cttgaccaac
    38101 ttgagtaata tttgttgctc ctgaatgtcc tttagtaaga agataatcat ctcctctatc
    38161 aaatatactt acagtagcat catcttcttg tatcttctta ccatcagatt caatcctagc
    38221 tacattctta tatttattac catgttttgc atttttgtca ctgattctag ccttatactt
    38281 aacagtatac gatttatcta tatttccaag attaactgaa atagaatttt tactctgttc
    38341 aatattaaaa tcactaactt cttttccatc acttgttact acacttacag aaccatttat
    38401 caatgtcaat ccttcaggaa gctcatcata caaaataata tcttttaact cttcctgctt
    38461 ttcatttact tgtatactgt aatttatatc tttattttta actggcataa atacagtagt
    38521 tgattttttt ccttcaacaa gctttttaag tgttccttta gcatctggaa catccgtttt
    38581 atctccaggt tttatttcta catctatatc tccacttcca ctttctattt ttccagtagt
    38641 ttcaatatgt atttttgcat tagtatcttc atcaaccttt ttaacatatg cttccaaacc
    38701 tattttacct tgcattacac tttggccatt aggtaattct ctaaatgtaa gtgtatactc
    38761 tccattactt tctgttttat caaagcattc acttgtataa tctaaattaa ctttattgaa
    38821 tacatctggc accttaaaag ttattgaatc tcctgcttgt attccttttg atgttggagt
    38881 ataagttaaa ttaaatgata tttttttcat tgattccgtt tctattgtat tgttattaat
    38941 ttttacaaca aatccatagt cttcattttc ttcattaagt tcttcttcta aaactttcaa
    39001 taaattttca ttttctaata gattatcttc ctctggagtt ttttctgtat ttttattgtc
    39061 tagtggtttt tcatcttcta aagcttgttc tgacttttta ttatctgttg acttatcttc
    39121 ttctggtatc tgctctggct ttttattatc tattggcttt tctccttctg gagtttgctc
    39181 tggcttttta ttatctgttg acttatcttc ttctggggtc tgttctggtt ttttattatc
    39241 tgttggtttt tcttcctctg gggtctgttc tggtttttta ttatctgttg ccttatcttt
    39301 ctctggagtc tgttctggct ttttattgtc gctttccttc tcctctccag ttgatgaatt
    39361 agttgaacca ctttgaatct gactattctc tcctaattcc gaagcataag atacagttgg
    39421 atatattgta gacaccacca tacttaaaat cataattaaa ctaattaata atgcctttct
    39481 atttcctttc ttcatgtaaa tctcacccct ttaggttacc tataatttat aatctaatct
    39541 tccattaata tcgtatataa agtaattttt actaaaaaat tatacaaaaa aagctatgaa
    39601 aataaataaa tttatattca tagccggttg caccactgac tcagtatatc cataaggtgc
    39661 ccaataatag aatatacttc aacatctcta taatatttca taaaaacaat taaaattgct
    39721 ttatttatat taaaaataca attatatact tctattatat tatgcctcta tactattgtc
    39781 tatccttttt acatttttta ccttatgatg agattaatta ataattaaat aaaatcctta
    39841 tctacaacaa ttacacaatt atattcagga tttatctcct taactaattt tgttatatct
    39901 tcttttaagt catcttctga catgtttttg gaaaattcgg aaggattaac tactatatca
    39961 aatattaaat tcttcttgct tccttttcca actattctaa aatcatgcat agattttaca
    40021 agactatttt tcttaagtat ttcttcaagt tcttttttgg ctgacataac ttctttatct
    40081 tcaagacata ttgggtccat gtgaattact agatatatat ctaatttttc agatatttct
    40141 ctctctgcag tatctataat ttcatgtatt tccattatat ctatgttgga tggaatttct
    40201 gcatgtatag atgcaataca tctaccaact ccatagttat gaataattaa atcatgtgta
    40261 cctattatat atttataaga taacaatagc tctataatag aatttaccat ttcttcatcc
    40321 ggtgcttccc ctaaaagagg atttatagta tcttttacaa gagagaaacc agcataaagt
    40381 atcactaatg atactacgat accaacatat ccatctatgg gaaaattagt aaatctagct
    40441 acaataaatg atataactac acaacttgaa gtaaatacat ctcctaaagc atcaagtgaa
    40501 actgctttta aggctgaaga atcaatttta tttcccataa atttattaaa acgactcaac
    40561 cagattttaa tcattataga tgcaattaaa agtataagtg gtattacttc aaattttaca
    40621 ggaattggat ttactatcct ttctatagat gactttacaa attgaagtcc aaccaacatc
    40681 accataaatg ctactattaa tgctgataaa tactctattc ttccatgacc aaaagggtgt
    40741 tctttatcag ctggcttact tgctaattta aaacctatca tagttattgc tgaagatgcc
    40801 atatcagaaa gattattaaa tgcatcagcc attatagcta tactagatgt gagcattcct
    40861 atgaatacct ttatcacaaa taaaagtaaa ttggataata tacctactac accagctaca
    40921 taaccatact tatttctaac atctgtattt tgaacgtttt cgctatctct gataaatgtt
    40981 ttgactagga ttttggaaaa catgaaactt acctccctgc cctttatttt attaacaaat
    41041 tttataatct atatctttat ttatgataac ataatttata tataaaattc ttaaaaatca
    41101 ctctacttca gtaaaatatt attctatata tctatttaga tacgaatttt atatttagta
    41161 aagtttttat ggcttagtgt ctgtttaata gattctatat aagtttttac aaagattatt
    41221 tattatgata atatcatttt tcccaagtat tacttagaat atgatttttt tgttttgtct
    41281 gtacatattt taaatttata ctatatttat ctatatttta taaccttatg atacactata
    41341 actataagat tttaaatgga aaggaatgaa ataaatcatg ttttttatca gtgatattta
    41401 cacaaaatca cctattaaat ttgatactcc tttgcaaaaa gaggcatata aaatattaca
    41461 aaaattagat attgactttg aatgtgttga cacagatgaa gcaattacaa tggaagattg
    41521 tgttcagatt aataaaaaat taaatatgaa aatggtaata taaaacaaca ttaaacaaac
    41581 aaaaaccgca aagttacaat atatagtact ttacggtttc ataagaatta atttttacta
    41641 ttaaagttca tagttctact atttttcatt gttctaagaa ttagctttac aaattcattt
    41701 gacaatagga tagtggatgc aaatagtatt atctttatcc acatatcaaa gtccaaagaa
    41761 acagaattaa agaaactctg gaacacttgt gtaaatatta tttgaattat ccctgtaact
    41821 actattattt gcaatgccag tttattttta aagaaatttg gtattgtact atttaaacca
    41881 aactctctac aatttaatgc attaaaaagg gcactgaatg caaataaaga aaatataaca
    41941 gtaccttgtt cttctgatgt agctcccaat atattaaaag ctgattgagt aaatacaatt
    42001 gtaattataa gaattgcatt tataataata tttacaaaca tagacctagc tattattcca
    42061 gaatgtctat ttattggttt tcttttcaat acataatctc taacaggttc taatcctaat
    42121 gctagggctg gaggaccatc cattattata tttacccata ataattgtat tgtagtaaat
    42181 ggcatatcct taccagtaag ttgagatatt atagcaatta taaatgctac tatatttaca
    42241 gtaagctgaa actgtataaa tctttgaaag ttctcatata tacctcttcc ccattttatt
    42301 ccctctacta tagtactaaa gctatcatca gtcaatatta tatctgctgc atttttagat
    42361 acttctgttc ctgaaatacc cattgcaatt ccaacatctg cttgactaag tgctggggca
    42421 tcatttatac catcacctgt tacagctaca acttcgccac ttttttgaag tgctgaaact
    42481 attctcattt ttgtatctgg tttacttctt gcaacaatag atattccttt gatttcttct
    42541 ctcaattctt tatctgtcaa tacatctata tatgttgctt caactgcctt tttcccatca
    42601 tttaataatc ctaattcatt tccaatagct gttgctgtat ttatattatc tcctgtaagc
    42661 atttttacat ctactcctgc attaaatgct ttatcaatgg aatctttgac cccttctctc
    42721 aatgggtcca ctattcctac aaatccacta aaaactaaat tatcttcctt catataactt
    42781 cttgaatttc ctattaaatt caattcacct tctgaagtca ttgcaacttc tgttttagaa
    42841 ttactcattt ttttataagc aaatcctaat gttctcatag atttaatttg taacttctta
    42901 atctcatcta aaatactttt ttctactttt ggagttattg gaacaatatt ttttccttgt
    42961 tgtacataag aacatttttt taataatact tctggagcac cttttgaaag taatatatct
    43021 gaatcctctt gacgaattaa tgttgacatc ttcttttctt ctgaactaaa tggtatttgt
    43081 gatatcaaat acgtttgttt tctcatttca ttatagttct tatcattatg atataaaagt
    43141 aatgcacact ctgttgcgct tcctatatat ttaaatgaat tatcttcttt ttctatatct
    43201 gcagttgaat ttactataca gttttgttca aaatagctat tactttgata ctctcctcca
    43261 cttatatatt taccatcaac atatgctacc tctaccatca ttttgttttg tgttaaagtc
    43321 cctgttttgt cggaacatat tacagaaaca gaacctatag tttcacaggc ttctttcttt
    43381 gttactaatg catttatctt tgccatcttt tgcattgtta tagctaaggt aatatttatc
    43441 atagttggca aaccttctgg aacagttgca actattaatg caatacaaac catatatgca
    43501 tttttagcag gttctaatga ttgtaagaaa gataatatac tgcttgtatc taaaattaac
    43561 ataccttttc tctgcatctg tataatcata aacatacaca ataaagtagc tattatgcct
    43621 gatattcctg ctattttagc acccaacttc cctaatttaa tttgaagtgg agtttgctgg
    43681 tcttcatttg ataaattctg tgctatctta cccatctctg tcttatcacc agtatgagtg
    43741 acaaccatta tgcccctacc atatgctaca agagtccctc caaataccat attgacttgc
    43801 tttgcaggta ttgcatcctg ttcgattatt tctgttttag aataaactac ttccatatct
    43861 aatacagcat cagcattctt agctacatca tcagattctc ctgttagcat atcttctcta
    43921 agtttcaaat ttatagactg tataagtctt ccatctgctg gtatcatatc cccagtttct
    43981 atatatacaa tatctcctgg tactaaatca ttttttgata ttttaattat cttcccattt
    44041 ctaagcacct ttacttctat attttctgtt aattttgaca gggcatgagc tgctttttta
    44101 gattttcctt cagttattat gcctatagaa attccaataa aaatagcccc taaaatacct
    44161 aatgcgtcat gtaattctcc cacaaaagaa cttattactg ctgctcctat gagaattaat
    44221 atcataggtt ctgtcaaact ttctcccaac tcgtcccaaa atgttctacc ttcttttata
    44281 gtaaattcat ttaatccata tctaagcttc ctttcttcta cctcattatc atcaagtcca
    44341 atttctggat ttgtttttaa gtattttaat acttctttgg taggtttatt ataatacctc
    44401 ataactttat cccccttgtt aattatctat aaggaattat atgcttatga tagcttgtat
    44461 attacttttc aaaaaaaata aggtgttgat taatcaacac cttatagtgg ttatatatta
    44521 ttaaatttta tgttacaggc tttataaatt gtgagctata caaatcaaaa tatttaatct
    44581 tcaaaatacc cttctggata taatggaaac ttagatataa gttcttgtgc ctctgcttta
    44641 cattcatcta atacttcttt attatcaata ttttctgcta ccttattcat tatccctgct
    44701 atctgtataa cttctttttc tttcagacct ctttgagata ttgatgtaag acctatacga
    44761 acaccactag ttacaaatgg tgattgtggg tcgtcaggta taacattttt attaactgtt
    44821 attcctacat attcaagagc tttttcaaat tgttttcctg taagattctt acttcttaag
    44881 tcaaccatta ctatatgatt atcagtacct ccacttacaa tactaaaacc atgtgaaatc
    44941 agttcagaag ctagagtctg agcatttact acaacttgct ccattatctt tttaaattta
    45001 tctgtactta aatataatag tgaaaaggct tttgctgcaa ctgtattaag atgtatagaa
    45061 cctaatgttc ctggaaaaac acctttatcg agtttctttg catgttctgc tttacaaagt
    45121 acaataccac ttcttggtcc acagaaagtc tttgtcgtag atgaagaaac aaaatctgca
    45181 taaggtacag gactaggtat tactttcgct gcgactaatc ctgcaacatg tgccatatct
    45241 accataaagt aagctcctac ttcttttgca acctttgata ttctttcata atctattaat
    45301 cttggatatg aacttgcccc tgcaattata agttttggtc tacattcttt tgcctttgct
    45361 tcaagagcat cataatctat acgtccagta tttgggtcta ccccataaaa ttcatattta
    45421 taaatgtcat gtaaaaaatt aactgcgcta ccatgtgtca agtgtccacc ttggtcaaga
    45481 cgcatactta aaacagtgtc atttggtttt aatattgatg aatatacaca atagttagct
    45541 gtagaacctg aatacggttg tacgtttaca tgttctgctc caaatacttc ttttgcacgt
    45601 tttattgcta gggtttcaag tttatctgct tcttcagaac ctgcttgaaa acgagcccct
    45661 ggatagcctt cttctgtttt atttgtaaat acacatccac ttaattcaag tacttctgtt
    45721 ggtgctgtac tttcagaagc tatcatctca atattgtgtt cttgtctaac caactcatca
    45781 gctacaatct tgtataactc tgggtctgaa atttttgttg tttttaacat aataatcctc
    45841 ctcttaatta aagaatatat tttattagtt taatcttcat tgataaattt attataacgg
    45901 tctataaaac gtaagatatt cctccaccag gtcctaatgg tatgccaata cccatgaata
    45961 gtaacaatat tattatttct attaatgtaa ataccactga gtatggaatc atattcgata
    46021 tgacagtacc tatacctata tctttatcat atcttctggc aaaggccaat ataactggaa
    46081 aatacggaaa aagtggactt attggatttg ttgaagcatc tccaatacga taagctattt
    46141 gagttaatgc tggattaaag tctagtagca taaacatggg aacaaatata ggtgctaaaa
    46201 tcgcccattt tgcagaagca cttcctacaa ataaattgat aaatccagat agcaatataa
    46261 atcctattat caatccatag ctaggtattc ccgactctgc tagtaatttt gctcctgtta
    46321 ttgataaaat tgttcctaag ttactaagat taaataaatt aataaactgg gatgctataa
    46381 atgctaggac tatatatcca cccatatcac tcatactact acccatcata gatactaaat
    46441 ctttgtcact ttttatcttc ttacttactt ttccatacac taatcctgga gttaaaaata
    46501 taatagtgat tataggaact atacctttca ttaaaggtgc attactagat agtatagaac
    46561 cagtctctgg atctttcata aatgcattgt cacctataca taaggcaact atcactacta
    46621 ctacaactaa caatgataat aaagcgtatt ttataccctt attttcaagt tcactcaatt
    46681 cctgtatatc cttatcattt gttgaatcat tatattttgt aaaacgagga gctataaatt
    46741 tttcagttac aaatgctcct gcaaaagtta aaactatcgc tgatataaaa gcaaaataaa
    46801 gattcattgc tggattgcct tggtaagatg ggtccatcat ttgagctgct ggtattgtaa
    46861 atccagctaa caatacatct gtagtactaa gcataacatt tgctgcaaat ccccctgcaa
    46921 cacctgcaaa agctgcaaac atacctacaa gaggatgtct tccaattcct aaaaacacaa
    46981 gtgctgcaag tggtggtaat attataaatc ctacatctgc tgctgtatgt gacaacatac
    47041 ctgcaaatac gattgctaca gttacaagtt tttgtggaac tttacttata ccctttttca
    47101 ttaacacttc cataaatcca gatttctcag caacacctgc tccaagcatt gtaaccagta
    47161 ctaatcctaa aggagcaaat gactgaaagt ttgtaactat gctacctaaa tatgattgaa
    47221 tctgctcttt ctctagtaga tttactacct ttacaacttc ttttgtagaa ggatgtattt
    47281 cttctactcc taaattagat ataactgctg acaatattac aacaattata catagtaata
    47341 aaaatatggt tactgggtct ggaagtttat ttcctgctct ctctacaaca tttagtgccc
    47401 tcatcaataa tccactatct ttgttttttt cctgtgaatt aattttcctc aaactaatac
    47461 cccctcataa actttatctc cagaatgctc tatcttaaat tttatttttt aatttatcca
    47521 tataatttat aacagactga catagtacat ttgtacctac caatatagaa tttttatcag
    47581 ctttaaattt aggattatgc cactgatata tacaatcttg ttctttgttg cctaccccta
    47641 accagtaaaa aaatcctggg gctttttcca tgaatataga aaaatcttcc cctcctgtag
    47701 aaggtattgg atcaactata gcatcttctg aatacaaatc acacacagac ttacaagcta
    47761 ttgcgtacat ctctttacta tttataacag ctggtaaatc aaataaataa tctagctttg
    47821 cagttgcttg atatccacga gctatctcac aaactatatt ttctaaattt tctgatattt
    47881 tctttcgtac ttcattacta aagcttctac atgtgcctgt catatctacc ttttctgaaa
    47941 ttacattatt tgcagtccct ccatttatag tacctattga tataacagct gattctaatg
    48001 gacttatgtt tctgcttact atggtttgaa tacccattat aattgcactt gatgctacta
    48061 tagggtctat tgttctgttg ggtatacctc cgtgacctcc aaatccattt acttctatct
    48121 taatagtgtc tactgctgcc attaacccac ctaacttaac acctattttt ccacaaggta
    48181 tatctggatg attatgaagt ccaaatatag catcaacttt tggattttcc attactcctc
    48241 gttccactag catcttcgca cctttattga cttcttcggc tggttgaaat ataaacttta
    48301 catttccatg aagactatct ctaatatgag acaatacata tgcacatcct acaaggcaag
    48361 acgtgtgtat atcatgccca catgcatgca ttataccatc atatctggat ttatacttaa
    48421 tatcaacctc ttcatatatt ggcaatgcat caatatctcc tcttagtgct actgtgggac
    48481 catcatactt cccttttaat aatccaacaa ctcctgtttc cattcctaaa tctaatattt
    48541 ctatgtctaa actcactaat aaatctttta tagcttttgt agtcctaaat tctttaaaac
    48601 ttaattcggg gtgcatatga atatctgtaa aaaaatctaa aatatcttct ttatactttt
    48661 ctgagattaa aataagttca tgcatactaa cacctctcca aaattttatt
//
LOCUS       DAEHWO010000024        48376 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEHWO010000024 DAEHWO010000000
VERSION     DAEHWO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48376
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.024"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            176..1051
                     /locus_tag="KNP54_001606"
     CDS             176..1051
                     /locus_tag="KNP54_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HBF0892511.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            1069..2559
                     /gene="cls"
                     /locus_tag="KNP54_001607"
     CDS             1069..2559
                     /gene="cls"
                     /locus_tag="KNP54_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBF0892512.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            2752..3036
                     /locus_tag="KNP54_001608"
     CDS             2752..3036
                     /locus_tag="KNP54_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBF0892513.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            3069..4697
                     /gene="groL"
                     /locus_tag="KNP54_001609"
     CDS             3069..4697
                     /gene="groL"
                     /locus_tag="KNP54_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBF0892514.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTESAVADLPEKEDAGMPGMGGGMPGMM"
     gene            4959..5699
                     /gene="larB"
                     /locus_tag="KNP54_001610"
     CDS             4959..5699
                     /gene="larB"
                     /locus_tag="KNP54_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBF0892515.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            5783..6517
                     /gene="larC"
                     /locus_tag="KNP54_001611"
     CDS             5783..6517
                     /gene="larC"
                     /locus_tag="KNP54_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBF0892516.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            6547..6966
                     /locus_tag="KNP54_001612"
     CDS             6547..6966
                     /locus_tag="KNP54_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBF0892517.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCSES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      7026..7127
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            7348..8883
                     /gene="guaA"
                     /locus_tag="KNP54_001613"
     CDS             7348..8883
                     /gene="guaA"
                     /locus_tag="KNP54_001613"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBF0892518.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(8960..10006)
                     /locus_tag="KNP54_001614"
     CDS             complement(8960..10006)
                     /locus_tag="KNP54_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBF0892519.1"
                     /translation="MPAYKDEQRKSWYASFYFTDFDGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRRWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGSIGKKNAD
                     EMNFWTLEEFKKFIEFEKKSEPRLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IRLNGEDIVSSPKTPKSKRVVPIPHFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LDRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(10083..10298)
                     /locus_tag="KNP54_001615"
     CDS             complement(10083..10298)
                     /locus_tag="KNP54_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892520.1"
                     /translation="MLKKLRKKKRMTQLELAEKMRRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKLQEIKRRGK"
     gene            complement(10732..11133)
                     /locus_tag="KNP54_001616"
     CDS             complement(10732..11133)
                     /locus_tag="KNP54_001616"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892521.1"
                     /translation="MQTLAEIIKEYRSEHNLSLREFSNLCGVSHTYIDKIEKNRDPRN
                     GKAVEPTLDMLEKMSFGLNLTLKELLTKLGKIQPNTQQDDELLKKVNSKEDNEVNELI
                     NRLASLDSDDKNAIKKMIDNAYYKAVNTKKE"
     gene            11298..11510
                     /locus_tag="KNP54_001617"
     CDS             11298..11510
                     /locus_tag="KNP54_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892522.1"
                     /translation="MKNNLQYIRKESRISQKKFADKIGISRPYLSRIENGKVNPSLEI
                     AHKISLETGKTINEIFFDFTVNHSKL"
     gene            complement(11805..12023)
                     /locus_tag="KNP54_001618"
     CDS             complement(11805..12023)
                     /locus_tag="KNP54_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892523.1"
                     /translation="MTKFKDNIKLVRKQMNMTQKQFASLFGISERAYQYYESGSREPN
                     IETLILISNKLNVSTDFLLGLSPNQNRN"
     gene            12142..12330
                     /locus_tag="KNP54_001619"
     CDS             12142..12330
                     /locus_tag="KNP54_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892524.1"
                     /translation="MNNNLKLQREKVGLTQLEVAQKAKITERSYQYYEAGERLPNIRT
                     ALKIARILNTNCEKLFNE"
     gene            12372..13136
                     /locus_tag="KNP54_001620"
     CDS             12372..13136
                     /locus_tag="KNP54_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBF0892525.1"
                     /translation="MNNLQLNNKNTITTLEIADMLEINHWEVLRKLEGTEKTKGIIDI
                     LNDNNFVVVDYFIKSAYLDLKNENRKCYNVTKLGCDFLANKFTGEKGIIFTARYVKRF
                     NKMEQELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQAMKPKADYFDALVERNLL
                     TNIRDTAKELGVKEKVFVSWLIEKKYCYRDSKDKLQPYANRMQYFEKKEFTNEYGYSG
                     VQTLINPRGREAIRLLLIKDGLIKEKEKGCQITLLG"
     gene            13183..13392
                     /locus_tag="KNP54_001621"
     CDS             13183..13392
                     /locus_tag="KNP54_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892526.1"
                     /translation="MAKAVAKEQLFYRAKDIAKFLDICEATAYKIIAELNEELEKEGF
                     KTFSGRVSVAYFKERYCYKPRKGVI"
     gene            13393..13533
                     /locus_tag="KNP54_001622"
     CDS             13393..13533
                     /locus_tag="KNP54_001622"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892527.1"
                     /translation="MNVKVLIAYIQFCNDKQIKASFEGLRKYNRDIELVNLYLPTHLK
                     IK"
     gene            13549..13761
                     /locus_tag="KNP54_001623"
     CDS             13549..13761
                     /locus_tag="KNP54_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892528.1"
                     /translation="MVFNLEEFKVGNAVRISCERFGFEIDCIVVVATEKELNLAYFDK
                     ERGCMEYQALIPEDLRYDDYILERLG"
     gene            13775..13945
                     /locus_tag="KNP54_001624"
     CDS             13775..13945
                     /locus_tag="KNP54_001624"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892529.1"
                     /translation="METAISIAKGQIEGANESIKELKSKENYDKESLRWWEGVKQASE
                     NILEFLEIENKA"
     gene            14027..15979
                     /locus_tag="KNP54_001625"
     CDS             14027..15979
                     /locus_tag="KNP54_001625"
                     /inference="COORDINATES: protein motif:HMM:NF022840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2813 domain-containing protein"
                     /protein_id="HBF0892530.1"
                     /translation="MKAILLKGLEIENFKGIKELRIDFNNITNIFGENATGKTSIFDA
                     FTWVMFDKDSKNRSVFEIKPLDKQNKVIRGLVTTVTAVLEVNNKEIKLTKKYEEKWTR
                     KRGESEATFTKNETTYMINDTPIKKSEYVKEIAEIADEEQFKLLTNPYFFSNELNWKK
                     AREVILEICGDITIEQIIESNKDLVLLTTEFEKENNIDKIIKNRKASKNNLSKEKEEI
                     PVRINECNKGMYNIDFEEIEVQLKAKKSDLEAIEDNLLNGTKTNEQILKDKEKIFELK
                     QETQSIKQSASKKGNKKRNELLKEKDELQYNIKNLRNNLVYLERDSELKETLRKRAIE
                     KTTNLRDKWTKKSQETLDLSVIQTECPTCKRPLDLEDIEEKKKEMLDNFNLNKAKELK
                     EIVELGKSKNDDVELFNTEIERLKVDINKTLEEIQEKAVLLDKIKKELESTKSTEIYS
                     ADEEKRLTEISVEIKELEEKINNKDNDKNIDELKESKKKLAVEIELLNKELAKRDINK
                     GLLDRKEQLLEKEKELGIELAHQEKILNLCELFIKTKVSLLESNISSKFKNVTFKLFK
                     EQINGGIEETCEALVDGVPFSNVNTAGQINGGLDIINTLSNHFGVKMPIFIDNRESVN
                     DLIDIDSQVINLIVSNDNPLKIKGVN"
     gene            15981..16850
                     /locus_tag="KNP54_001626"
     CDS             15981..16850
                     /locus_tag="KNP54_001626"
                     /inference="COORDINATES: protein motif:HMM:TIGR00616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBF0892531.1"
                     /translation="MANEIQRQVSVKNLLSTEAYKKRFKEVLKDKANTFMASVVNVSN
                     LPSLKDAEPNSILKSAMVAATLDLPIDPNLGFSYLVPFVNKGVKEAQFQIGYKGFIQL
                     AMRTGQYKTINAIEIYENEIKSVNRLTGEIEFNENKDEIDNEIVVGYIAYFKLLNGFE
                     KTLYMSKEDMEKYAKRYSQTYKSNKDYVVKSSLWTTDFDAMAVKTVLKRLLSKYGILS
                     IEMQKALETDQAVIKDDNSVEYVDRQVEEEIEENANKKTIDMTTEEKEKAIEIKESKP
                     EEATQVELDTPPF"
     gene            16853..17566
                     /locus_tag="KNP54_001627"
     CDS             16853..17566
                     /locus_tag="KNP54_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015615677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0892532.1"
                     /translation="MKIKVLGSSSRGNCYLLQLKNETLILECGVSYKEILKGLDFSLE
                     NVVGCLVTHEHKDHSKAITELTNNGIDVYSSKGTLEALKIENHRTKIIESEKLFKIGN
                     FKIVPFNTKHDAVEPLGFLINHSSFGNLLFITDSYYCEYNFNNLNHIMIECNYSKDLL
                     DNNKDKIYLRNRIVKSHFELSNVINFLKVNDLSNIKTITLLHLSEDNSDKDLFIREIE
                     KNVGVPVIVAEKGLEIYLD"
     gene            17724..18470
                     /locus_tag="KNP54_001628"
     CDS             17724..18470
                     /locus_tag="KNP54_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBF0892533.1"
                     /translation="MEMQTGYNRETVEKLIKRFIEYGKIKYDSTTKEILIINWSKHNF
                     SKSPKVRTCILKEVESIKNKEFQQYMYRVCIDYGYPIDTVSIDYGEKEKEKQKEKEKQ
                     KEKEKQKEKVEPLICEEQEKNELKEFKKLYEENIGVVYPVTAEWLIEISSDVDIRLFK
                     SAIEICAEKMNMNIAYLKGILKKWKDANITTYEQLESYRLQQENKKAKKVVNGQLSKN
                     KFANFEQTFTKYTENELDNIIKKSQDAKFK"
     gene            18528..18875
                     /locus_tag="KNP54_001629"
     CDS             18528..18875
                     /locus_tag="KNP54_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892534.1"
                     /translation="MGKIWMDAGTFLETKDIGDIECNLREMINKNKQKNLIGRINSKG
                     QGRKSKKVECTNIITGESKIFVSAVEASEYLYFTELHITRLARTGKTTKNGWKVRYIE
                     EVSNGISKCGTSN"
     gene            18844..18981
                     /locus_tag="KNP54_001630"
     CDS             18844..18981
                     /locus_tag="KNP54_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892535.1"
                     /translation="MVLANVEQVIKLAEKILSKKKCSVNKAIDIAIKILNRYEYEGMI
                     K"
     gene            18978..19427
                     /locus_tag="KNP54_001631"
     CDS             18978..19427
                     /locus_tag="KNP54_001631"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892536.1"
                     /translation="MSLIEYRGYDFENKKWIYSKTIMWSNAVDCLLMLKEDFKWRKVC
                     NVGICSEEWAGNNQEIFEGDILKENYNPHNRSSYGIVKRDFNSIKLYLEWHYLKKFEG
                     EWIEIIDKTEIYHSRGYKVIGNEYENLEEVRKEFLERKEMLENERLS"
     gene            19529..19687
                     /locus_tag="KNP54_001632"
     CDS             19529..19687
                     /locus_tag="KNP54_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892537.1"
                     /translation="MNDRLEMINASVNYIQMICESSNIAIIAEHDRVRILDLETKEKY
                     DLLRSEGD"
     gene            19691..20014
                     /locus_tag="KNP54_001633"
     CDS             19691..20014
                     /locus_tag="KNP54_001633"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892538.1"
                     /translation="MSKVIQCDFCKEIFEKYNGECIELYKKDCSKGVLGIDKHICPTC
                     YEKFIEGKIEKVENAKRFKDKLIDFLVEHEVCDCCACDCVFDSNDEKKCKAGIREWVE
                     SEVEE"
     gene            20016..20315
                     /locus_tag="KNP54_001634"
     CDS             20016..20315
                     /locus_tag="KNP54_001634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892539.1"
                     /translation="MAKLIVSIPLTKYLKDITKEWGETYITKTYGGHVYLSDEAPGEV
                     LKKEDDLNYIEFNDSDIVMRLPKEVHQHINLKKGCNKNLKDVLKEIKKIEEKTNI"
     gene            20423..21319
                     /locus_tag="KNP54_001635"
     CDS             20423..21319
                     /locus_tag="KNP54_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBF0892540.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFKGRRSSLFFAVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLIELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFVVGHFRGRSTRKVFPIERKSRKNLEQLNNPTHSTSGVLVNAVLTPDRVNKRQN
                     GRRIKESGEPMFTLTAQDKHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDSQ
                     LYKQAGNAVTANVVYEIAKRMG"
     gene            21398..21619
                     /locus_tag="KNP54_001636"
     CDS             21398..21619
                     /locus_tag="KNP54_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892541.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKQKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMAEYYCDGGIEI"
     gene            21616..22620
                     /locus_tag="KNP54_001637"
     CDS             21616..22620
                     /locus_tag="KNP54_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBF0892542.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDIEAFFQKKISKVSR
                     DNDIRTVVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNAILESCDLA
                     ICLYSQKDEKKVAILKLDYNNSYTHSISFEEDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDEYHLKVLDKDAEKEEANSKFVTEFLNATKVKDDKYRTKKFKDTVENWITNVL
                     GNDIKQAEDIRSILNYTLKEKHEIDIKDFVDKSIKDDELKNSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIIIKNVNFYNEK
                     "
     gene            22631..22921
                     /locus_tag="KNP54_001638"
     CDS             22631..22921
                     /locus_tag="KNP54_001638"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892543.1"
                     /translation="MENKDNFVLNKLGPASKVMKKVEIDEKEIKSYLKELKECEEVKV
                     FIIRKDGIEIPIVFKDGNMNEWLRKEIEISFDRFKDEIAQVKKALIKVTGEN"
     gene            22941..23108
                     /locus_tag="KNP54_001639"
     CDS             22941..23108
                     /locus_tag="KNP54_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892544.1"
                     /translation="MTNKEMCKSNNLDEREVCKEFGKEICGSCINDRVDCESKDCDIA
                     YENWLEKNTER"
     gene            23194..23535
                     /locus_tag="KNP54_001640"
     CDS             23194..23535
                     /locus_tag="KNP54_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HBF0892545.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNLKVCESYIEGKNELYK
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEVLEEELIK
                     INSHLELEDLN"
     gene            23661..24068
                     /locus_tag="KNP54_001641"
     CDS             23661..24068
                     /locus_tag="KNP54_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBF0892546.1"
                     /translation="MKVFLVIDGEPVGKERPRMNTYAKRTYTPNKTKNYEDLIKWLYQ
                     SKVKYYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVIKVVADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDVI"
     gene            24170..25024
                     /locus_tag="KNP54_001642"
     CDS             24170..25024
                     /locus_tag="KNP54_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBF0892547.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRELKHINELINNNIKRFKTNIDIIDLKVSRSERLGDLKANPFEGLGYEDVGYSKQS
                     FNQSRNIYLLSERGYSKLLKILEDDKAWEQYEKIVDGYFSMRKELNNPLLSASKELQA
                     IFMLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKA
                     YKNKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNNYKLPIVFEEEIRLL
                     NSQLSIVS"
     gene            25176..25682
                     /locus_tag="KNP54_001643"
     CDS             25176..25682
                     /locus_tag="KNP54_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892548.1"
                     /translation="MSKTKKEFFNATKKQLSNYKQLSANIIKLKNEIQMLKDNSVGDL
                     MKGISYDSVKTGKTNKTSNMIEDAIVNVSDLITEKEIELYEAEIIKSTIDLAIRNLKP
                     IHRQIIELKYIDGLMWQEMVDIVHLEERQLSVRASQAISSISIALFGKKALIEQEPLF
                     ELLDYKLN"
     gene            26435..26608
                     /locus_tag="KNP54_001644"
     CDS             26435..26608
                     /locus_tag="KNP54_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892549.1"
                     /translation="MATKSILKNVDVRKKAFGRNLVSALENAKNKQEKEVVLSKKCSE
                     VPKDKIKDIFGRF"
     gene            26608..27219
                     /locus_tag="KNP54_001645"
     CDS             26608..27219
                     /locus_tag="KNP54_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBF0892550.1"
                     /translation="MSGYLIVNLSNMLGELEEEEVKKILSSFSCPLNKDVEDFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIVGYFTLANKYFTIKRKTLTNSLARKVVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            27296..27922
                     /locus_tag="KNP54_001646"
     CDS             27296..27922
                     /locus_tag="KNP54_001646"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892551.1"
                     /translation="MKKITKLILCSLLVISIASPLQVEAKTTHHSSSHVSIHKSSTKS
                     KSSRPKITKTKKATKTYRTNKSIKKKIKLKKQVNKKTQVPNKQAARKDKKTTTYNYYN
                     SYNSNRYYTTSSSGLSFWDCYMLGHLFNNNNKVSEQDIARELQKQGYSKQETDNILRK
                     ANQNQAKKEEKKKRVMMLIFSVLGALFIIGLGLIIFIKRESKGCNKSM"
     gene            27995..28684
                     /locus_tag="KNP54_001647"
     CDS             27995..28684
                     /locus_tag="KNP54_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892552.1"
                     /translation="MNEKADLAHEDYLKGLKYKEIAEKHNVSLSTVKSWATRYWKQKG
                     CNQSKKVATKKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELMQEISIKDKFD
                     ILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASF
                     LNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDELK
                     ISVDYGDRNDS"
     gene            28662..29915
                     /locus_tag="KNP54_001648"
     CDS             28662..29915
                     /locus_tag="KNP54_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBF0892553.1"
                     /translation="MVIEMIVRVNFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSSTHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANVVL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSKGLEKNIFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            29930..31360
                     /locus_tag="KNP54_001649"
     CDS             29930..31360
                     /locus_tag="KNP54_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBF0892554.1"
                     /translation="MYISETDLIKVQLKKESTFNLVKVIEHYILKHRPEKYKQGEEYY
                     YGNADINNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNADDD
                     NLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIPIWD
                     SKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFIQEFLYDEYGKMT
                     DIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNLDEI
                     QEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRLEKN
                     IIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEYLKI
                     SGNKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDELER
                     LKKQEDTQKEYDDLIPNNQDGVIDET"
     gene            31350..32711
                     /locus_tag="KNP54_001650"
     CDS             31350..32711
                     /locus_tag="KNP54_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013657754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBF0892555.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSIKYYLELEKQYKLAMSNIEKDI
                     LIWYNRFTENEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKVLV
                     NEFSKKFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCHCRTTTAPWFEDEEGYRAARDENGKTYYVPSGMKYK
                     EWYEKTFITDKKDDILSNKSWLKADFPTEKKFKKHVEKHLNEYGNITAEEYLSTARNL
                     LSEQLSNDVEGFLSKDNFLFKYRKSTNDFAVGRADGKISTLFKPKEGYNYWLEQIKEY
                     KEV"
     gene            32714..32875
                     /locus_tag="KNP54_001651"
     CDS             32714..32875
                     /locus_tag="KNP54_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003495392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892556.1"
                     /translation="MNCPVCGKDVDVFDICDNCNWQNSGPKETNYKGPNKMSLKEAKE
                     AYEKGKKVI"
     gene            33207..33599
                     /locus_tag="KNP54_001652"
     CDS             33207..33599
                     /locus_tag="KNP54_001652"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892557.1"
                     /translation="MAKFKKKSEEVEAFKWILGSPNTPIWFYQAFEKGTIWLDESLNS
                     VNRKGEVKKTICIKYKNGVIRATNGDWIIKDSEGKIYSCTCDEFEKYYKDLDNETKIS
                     NGGLECLREIALKDVNFKFELTGIKEEK"
     gene            33600..33797
                     /locus_tag="KNP54_001653"
     CDS             33600..33797
                     /locus_tag="KNP54_001653"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892558.1"
                     /translation="MFYLLLQVISICLSITVFMYVTGNIVFKIYLKSLRKEYESNIHE
                     VSDEILKRIRKELNKSLDESL"
     gene            33840..34070
                     /locus_tag="KNP54_001654"
     CDS             33840..34070
                     /locus_tag="KNP54_001654"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892559.1"
                     /translation="MKEYMIWFKSGNSISGIVDEDVADKLMQDFMEADSDCKDLKVYL
                     DEDGTTVIDLSQIEAISINNCNENNNIGFSKS"
     gene            34115..34678
                     /locus_tag="KNP54_001655"
     CDS             34115..34678
                     /locus_tag="KNP54_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBF0892560.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTITKEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            34690..35589
                     /locus_tag="KNP54_001656"
     CDS             34690..35589
                     /locus_tag="KNP54_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBF0892561.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            35589..35822
                     /locus_tag="KNP54_001657"
     CDS             35589..35822
                     /locus_tag="KNP54_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892562.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            35832..36233
                     /locus_tag="KNP54_001658"
     CDS             35832..36233
                     /locus_tag="KNP54_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892563.1"
                     /translation="MENNMIDDIERRLQGFGYVLKDGDKWLIDFVREKIENIIKLDCN
                     ISEIPKELHNIEIDMIAGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLVAYLTTYGKNNILTFRCLRW"
     gene            36227..36574
                     /locus_tag="KNP54_001659"
     CDS             36227..36574
                     /locus_tag="KNP54_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892564.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            36574..36999
                     /locus_tag="KNP54_001660"
     CDS             36574..36999
                     /locus_tag="KNP54_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBF0892565.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            36992..37429
                     /locus_tag="KNP54_001661"
     CDS             36992..37429
                     /locus_tag="KNP54_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892566.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            37422..37598
                     /locus_tag="KNP54_001662"
     CDS             37422..37598
                     /locus_tag="KNP54_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892567.1"
                     /translation="MNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINKFMKGVS"
     gene            37599..38909
                     /locus_tag="KNP54_001663"
     CDS             37599..38909
                     /locus_tag="KNP54_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBF0892568.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDKDLVESSLIYWATGAIAGC
                     DINKSNTNKKYDGEFDVGVNYTQIQLEEALKSGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            38931..39401
                     /locus_tag="KNP54_001664"
     CDS             38931..39401
                     /locus_tag="KNP54_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBF0892569.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            39454..39711
                     /locus_tag="KNP54_001665"
     CDS             39454..39711
                     /locus_tag="KNP54_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892570.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKSIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            39716..40156
                     /locus_tag="KNP54_001666"
     CDS             39716..40156
                     /locus_tag="KNP54_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBF0892571.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPILNKKGKATGQYTSETDFNTYTLKLCVETIVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            40156..40350
                     /locus_tag="KNP54_001667"
     CDS             40156..40350
                     /locus_tag="KNP54_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015390885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892572.1"
                     /translation="MYEGDYDSNIAHYCLHKFKWKPHEYMDLPVDEKAFVAASIDIKV
                     EEEKEEAKKADKDAKRGRRR"
     gene            40418..41209
                     /locus_tag="KNP54_001668"
     CDS             40418..41209
                     /locus_tag="KNP54_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBF0892573.1"
                     /translation="MGLFSKKNKKPCCICGSEKGLMPSIEGENFCTACNCKYIDFSEN
                     ILKVTSIMKMMSNSEGMKKFIEVEKKNLKLLEKFTETKSINSSISFDEEQNLLKISYK
                     NRNQILVEKIIKFDDILEFELLEDGETIVKGGLGRAITGGVLFGGTGAVVGGITGKKT
                     SRKVVEIFKIKITVKDINNPIEYINLINSKVKTNSSIYQKAFSDAQEILSILSIITKY
                     NVMEDKKKSISSSTADEILKYKNLLDMEAITQEEFDAKKKELLNL"
     gene            41276..43618
                     /locus_tag="KNP54_001669"
     CDS             41276..43618
                     /locus_tag="KNP54_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBF0892574.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMNNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIRESDNQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQLSDGGLNKMIFQSAERSRASYLDTAK
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTLGQIFTSVKNNAVMVFGAIQKKIEDTVSSRGFRTFITDVKDSLYVLGAVGFNV
                     FSGFINLLSSPAFQNFFNVMIVGTSLVVQGLGWIITQALSVANVFSRNWSIISPIILG
                     VVSAISTYIIALGIMQAVTIAGTVANWMSWTSEVIRQRGILGTARALAIGKAEQWGFN
                     AAIYACPIFWIVLGIIAVISAVFILVAVYNHFAGTSISAISLIVGAWYWLCAVVYNVI
                     VGIVNAINICVVEIANIFRTGLYAVQCFFIDMANAGLKAGVNLDKAFDKFATNLANGI
                     IKAVNIAVKGLNWLVQQINKIPGIDLPQMKEFQKVNTVIGTKTTFKPIQKPPEPKAWK
                     PELVEYKNLKSEFIKGYDVGHQLQNKFKDTFDISKIAEKAKKDLGLDDLWDKKYGLGD
                     GLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVN
                     IKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            43634..44335
                     /locus_tag="KNP54_001670"
     CDS             43634..44335
                     /locus_tag="KNP54_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBF0892575.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNMKVSLEEYNIVEDADNGSDVKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPTPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     VPKYTIYKGQVLKLG"
     gene            44328..46301
                     /locus_tag="KNP54_001671"
     CDS             44328..46301
                     /locus_tag="KNP54_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBF0892576.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDEFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLDLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSTTSKEDNDMINKLNKVFKNKLSNTGSIFVKYSNAYK
                     VNAALMAAISIHETGNGSSSLCKNKNNFFGMKGMSFGSVDEGIKRGISNLSRNYIHMG
                     RKTLESIRDKYAPLYDSPLNKHWVPGVNKFYKQITGNAYSSNSAGTGVRSNEEAEKNL
                     KDITYQVQNSNNANTSTNNNSKVNKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAF
                     KRGAGINLKRVSADQSNDSRGKLLCNINDVKAGDLVFFAYNQGKGNVHHVGLCIGNDK
                     FIHSPNTGDVVKISSLSGRQKQKHDFARARRFF"
     gene            46315..46575
                     /locus_tag="KNP54_001672"
     CDS             46315..46575
                     /locus_tag="KNP54_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBF0892577.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMQIAFGTIESVNPLVVKIEQKA
                     SFEESFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            46580..46999
                     /locus_tag="KNP54_001673"
     CDS             46580..46999
                     /locus_tag="KNP54_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBF0892578.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFQNVKGKVHCKFTVYSKYGNIKAEKVVSV"
     gene            47000..48049
                     /locus_tag="KNP54_001674"
     CDS             47000..48049
                     /locus_tag="KNP54_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBF0892579.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPIDSRFNLGE
                     YNYVAIERISEKTYKMKCETTGPVFELGQLIPIEYVDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSSDLVNLVQEEIDPLQNQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINSIASNL
                     NVDKDSIVLRGEVVG"
     gene            48042..>48376
                     /locus_tag="KNP54_001675"
     CDS             48042..>48376
                     /locus_tag="KNP54_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBF0892580.1"
                     /translation="MDKEINLINYLPQILRDKEEYIKVFNVENKEIKTLHEKLNDLSN
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELT"
BASE COUNT        19846 a         4988 c         9137 g        14405 t
ORIGIN      
        1 ttcatttttt atttaaggta aaaatttaaa gtaaaatatt attttacata ataataacct
       61 tataaatttt gaaattactt atctttgtgt taaaataagt aaaatgcaca tattagagct
      121 aagtttttaa gtaaataaac aaaatgaaaa tataaatatt aaggagattt ggtatatgaa
      181 tgtttatgaa aaaggtaatg gagttatact agaaggagta acagattttg acccagtaca
      241 tatatttgag tgtggtcaat gttttagatg gcacaaacaa gaagatggct catacactgg
      301 agttgcaaag ggaagaatat taaatgtcaa aaaagagaat gataaaatat atttaaataa
      361 tactaattta aaggagttta acagcatttg gtataattac tttgatttag gaactgatta
      421 tacagaaata aagaataagc taaaaaatat ggatgaatat ttaaataagg ctactgaatt
      481 tggatgggga ataagaatat taagacaaga tggatgggaa atgcttatat catttataat
      541 ttcctctaat aataggattc ctatgataca aagagcgata gaaaatttat caagaaagtt
      601 tggtaagtat ataggtgaat atgaaggtaa tgaatactat gcattcccaa caccagaaga
      661 actaaataag gcctcacaag aggaaataag agcatgtcaa acaggtttta gagataagta
      721 cataaaaagt actacacagg cagttataga gaataatgat gaggtatctg aatatacaaa
      781 tttaagtaca gaggattgta gaaaagagct tttaaaattt aatggagtag gaccaaaagt
      841 atgtgattgt attgcattat ttggtatgca aaaatatgat tcttttccag ttgatgtttg
      901 ggttaagaga gttatgcaag aattttatat agatgaagac atgagtttac ctaaaatgag
      961 aacttatgga atcgataaat ttaaagaaat gtctggattt gctcaacagt acttatttta
     1021 ctatgcaaga gaactcggta taggaaaata aattaagggg gagaaattat gggagtaata
     1081 ggaacaatat ttctgttcta tttaattata tcatatctag ctggagccat aatttctgtg
     1141 attatattgc ttgaaaatag agaccctgca aaaacaatgt cttggctatt gatgtttatt
     1201 atatttccag gtgtaggttt aatgatatat gctatttcag gtagaaatat tagaaaaaga
     1261 aaattattta agactcaaaa actagctaat aatataaaag aaaagaaact atttgataca
     1321 ttagaaaaga taacagaaat agttgaatta gaaaaagaat ctataaaaca aaataagctt
     1381 ttaagagatg aagaggatgg tagttataga aaaagggtaa taaatatgtt gttaaagact
     1441 ggtatgtttc cctttactaa aaataataaa gtggatgtat ttgtagatgg aaatgaaaag
     1501 tttaaaagac ttatagaaga tataagagaa gctaaagacc atattcattt agagtacttt
     1561 atcatcaaag atagtgaaat aggtagggtg ttaaaagaag aacttataaa aaaggctaaa
     1621 gaaggcatta agataagaat tttatatgat gatgtaggat gctggagatt ttggtttaat
     1681 agaaaatttt ttcgagaaat gagggaagta ggtatagaaa ttgcagcatt tttacctaca
     1741 aaatttccta taataggagg gaaattaaac tatagaaatc acagaaaaat tgttgttatt
     1801 gatggaataa ttggatatac aggtggaata aatataggag atgaatattt aggcaaaaat
     1861 gataagtttg gatattggag agatactcat attagaatta agggtatttc tgtatacatg
     1921 cttcaaatga catttctgat tgattggtat tatacgacaa aagaagtatt agtgactaaa
     1981 aattatttcc caagtgtagg gaatgttggt gaaagtatga tacaagttgt tgcgagtggt
     2041 ccagacagtg actgggaaga tattcattat gcttattttt ctgcaatatg tcaggctaga
     2101 aaaaatgttt atatagaaac tccatatttt attccagatg aaagtctact aaaagctata
     2161 aagagtgctg ctcttagtgg agttgatgtg agaataatat ttcctaaaat tgcagaccac
     2221 aagatagtaa atatagcatc ttattcatat tttgaagaaa tattaagagc aggtggtaaa
     2281 gtttatttat ataataaagg atttatacat tctaaagtcg taataataga tgataaaatt
     2341 gcttctgcag gtacagctaa tatggattta agaagtttta tgcttaactt tgaggtaaat
     2401 gcatttatct atgatgaaga agttattagg gtaatgacag atgatttctt tgaggattta
     2461 agtcactgtg aagaacttaa tttggaggta tttaagaata gaaatatcat acaaaaaatc
     2521 aaagaatctg tagcaagatt attttcacca atattataaa aaattattaa aaaaggtatt
     2581 gaaaattatg tgtgattggt atattataat aattgttagc actctattag atagagtgat
     2641 aataaataaa aagtatatat ataaatctac atatataagt agtattaatt taaaaataac
     2701 taaaaacata ggcgaactag tctatactta atattttagg aggcgtgaat aatgaaaata
     2761 agaccattag ctgacagagt agtaattaaa aaagtagaag cagaagaaaa aactgcaagt
     2821 ggaatagttt taccaggagc agctaaagag caacctcaaa tagctgaagt tgtagaagtt
     2881 ggaccaggtg gaatagttga agggaaagaa ataaaaatgg aattgacagt aggagataag
     2941 gttatattcc aaaaatattc tggaacagaa gttaagatag aaggacaaga atacacaata
     3001 ctaagacaga gtgatgtatt agctgttatt gaataaatat agaataaatt tattaggagg
     3061 ggtttaaaat ggctaaagaa attaaatttt cagaggaaac aagaagagct ttagaagctg
     3121 gtgtaaataa attagcagat acagtaaaag taacattagg acctaaagga agaaatgtta
     3181 tattagataa aaaatttggt tctccactta taactaatga tggagtaact atagcaaaag
     3241 agatagaact agaagataga tttgaaaata tgggtgctca attagttaaa gaagtagcaa
     3301 ctaaaactaa tgatgtagct ggagatggta ctacaactgc tacagtttta gcacaagcta
     3361 taataagaga aggtttaaag aatgtaacag caggggctaa cccaatactt ttaagaaaag
     3421 gaatacaaaa agcagtaaca gtagcagtag aagaattaaa aaatcaatca agaatagtag
     3481 aaacacaaga ggctatatct caagttgctt ctatatctgc tggtgatgaa gaagttggaa
     3541 aattaatagc agaagctatg gaaatagtag gtaaagatgg agttataact gttgaagagt
     3601 ctcaaactat gaatactgaa ttagatgctg ttgaaggtat gcagtttgat agaggatttg
     3661 tttctgcata tatggttaca gatgtagata aaatggaagc agttttaaac gacccatata
     3721 tattaattac tgataaaaaa atatctaaca tacaagaatt attaccagtt cttgaacaaa
     3781 tagttcaaca aggtaaaaag ttattgataa tagctgaaga tgtagaaggt gaagcattat
     3841 ctacattagt agtaaataaa ttaagaggaa catttgatgt agtagcagtt aaagctccag
     3901 gctttggaga tagaagaaaa gaaatgcttc aagatatagc aatacttaca ggtgctcaag
     3961 taatatcaga agaattaggt tatgatttaa aagaagctga tttatctatg ctaggtagag
     4021 cttcatctgt taaggtaact aaagaaagta ctacaatagt agatggttct ggagataaaa
     4081 aagctataga agatagagta actcaaatta aacatcaagt agagcaaact acttcagatt
     4141 ttgatagaga gaaattaatg gaaagattag ctaaacttgc tggaggagta gctgttgtaa
     4201 aagttggagc tgctacagaa gtagagttaa aagaaagaaa gttaagaata gaagatgctc
     4261 ttaatgcaac tagagcagct gtagaagaag gaatagtagc tggtggagga actgcttttg
     4321 ttagtgttat accagcaata ggaacactaa ttgagagttt agaaggagaa gttaaactag
     4381 gtgctcaaat agttaaaaaa gcgttagaag agccattaag acaaatagct ataaatgctg
     4441 gtcttgaagg tgctgtaatt gtgcaaaatg ttgttaattc tgaagcagaa actggatttg
     4501 acgcattgaa tgaaaaatat gtaaatatga tagaagctgg tatagttgac ccaactaaag
     4561 ttagtagaag tgctttacaa aatgctgcat caatagcaag tactttctta actactgaat
     4621 ctgctgttgc tgaccttcct gaaaaagaag atgcaggaat gccaggaatg ggtggcggaa
     4681 tgcctggtat gatgtaattt aaaaaattta aaatataaat tttaatataa agaactattt
     4741 cgacttagat tttaaactct aagttgaaat agttcttttg tatatatcta atttttgtat
     4801 atctataaat tcaatacaca tatttagata atcagtatct agtttgtaat aatattttag
     4861 agtagtattg ttatttttta ggttatgatt ttagatatat attaattaag gtataattgt
     4921 tgatagagaa taaatcaaat ttaaaaggat gcgataatat ggacttaaga aaattgcttg
     4981 aagaagttaa aaatgaaaat attgatatag attttgcgtt agaaaagtta aaagatttac
     5041 cttatgaaga ccttggatat gcaaatatag accatcatag agaattaaga aatgggtatc
     5101 cggaagttat ttattgtgaa ggtaagagtg atgagcatat tttagggatt attgataaaa
     5161 tgaatcaaaa aagttctaac atattgggga caaggtgcag aaaagaaact tttctgaaaa
     5221 ttaaagaaat ctataatcat gctgagtacg aagaggcgtc taaaattctt aagattcaaa
     5281 atcatgatat agagaatata ggaaaaggta aaattgtgat tgctacaggg ggaacttctg
     5341 atataccagt agcagacgaa gcttatcata cagctaagtt tttaggtaat gatgttgata
     5401 gaatatatga tgttggagtg gcaggtatac ataggctttt aaataaaaga cataaaatag
     5461 atagtgctag agtaatagta gccgttgcag gtatggaagg tgctcttgca agtgtaattg
     5521 gtggactggt tgatgttcca gtaatagctg ttccaacttc tgttggatat ggagcaaatt
     5581 ttggaggatt agcagcattg ctagctatgt taaatagctg tgcatctgga atatctgttg
     5641 taaatattga taatggattt ggagcaggat atttagcatc aatgataaat aaactgtaaa
     5701 tacattgata taaattaaac aaaactatat aataaaattt aatttctatt atatttttac
     5761 tattaaaatt gaggagacat atatgagtga aaaaatactt tattttgata taataagcgg
     5821 tatatcaggg gatatgaccc ttgcaagttt attaaattta ggtgtgccta aggaaatttt
     5881 tttggaggaa attcataaac taagaatgag cgatgaattt aatataaaca tcagctcgaa
     5941 aactgaaaat ggaatagtag gtacaaaagt agaagtaatt acaaaagaaa aacatacaca
     6001 tagaaattta gtggatatat ttgaggttat agataaaagc actctaaacg aaaatgtaaa
     6061 atctaaagca aaaaaaatat ttatggtaat tggagaagca gaagcaaaag ttcatggaac
     6121 tacaatagac aagatacatt ttcatgaggt aggggctata gattcaattg tagatatagt
     6181 aggagcttct atattagttg acttactttg tgtagataaa gtttgtgcta gtacagtgtc
     6241 tgttggttca ggatttgtaa aatgtgaaca tggaattata cctatacctg cacctgcaac
     6301 tatagaaatt ttaaaaggtg tgccaattaa attaaataat gtaaatggag aatgtacaac
     6361 tccaacagga gctgcaatca taaaagtttt gtgtgatgag tttgtagatg agcttgaatt
     6421 ttctccaaag caaattggat atggtatagg tcataagaag tttgaagtac caaatatact
     6481 cagaactgta ttaggtgaaa aaaaaaagaa gaattaattt atgaaattag tgcaaacatt
     6541 gatgatatgt cttcagaaat ctattcttat ttgtatgaaa aaatattaga tgagaaagca
     6601 ttggatattt atacagagag catttatatg aagaagaata gaccagcaac aaaagtatca
     6661 attttatgta gtgaatcaga tttagaaaaa tttattaaaa tattactttt agaaactagt
     6721 acttttggag tgagatataa tgcatataat agagaaattc tagagagaaa atttgtaaaa
     6781 ttagatacaa aatatggagt ggttacagta aaactagggt attataaagg aaaactagtc
     6841 aaggctactc cagaatataa tgaatgtaaa actatagcaa aaaatgaaga tattcctata
     6901 aaaaaagtgt ttgctgatat aaattttaga ataaaagaag aatttagtga aaacttattg
     6961 acataagtaa taaattttga taaattaata ttcagcctta ttaaataaaa gtaaacagaa
     7021 aaaaatatat aaaatataaa ctcactcgta tatgctcaga aatatggtct gagagtctct
     7081 accaagatac cgtaaatatc ttgactatga gtgaaattat tataccaaaa gacctagtta
     7141 agtaaatgtg taggctgagt taaactccct atgtgttggc tataagataa aggtattttg
     7201 gaagcctgta tagtaatttc acttttgcta gaaattatgg aagttactat acaggttttt
     7261 tgtgtaaaaa gatttaatat aatttagact gtattgtgtt aaaataaata tataaaaact
     7321 atattataca aggagagatg tgaatttatg aaacatgaat tagtacttgt aatagatttt
     7381 ggaggacaat ataatcagtt gatagctaga agagttagag aaaacaacgt atattgtgaa
     7441 atacttccat gtactgcaag catagaaaga ataaaagaaa aaaatcctaa agggataata
     7501 tttacaggcg gtccaaatag tgcgtattta gaagattctc caacaatatc aaaagaaata
     7561 tttgaattag gagtaccaat acttggaata tgctatggta ttcaaataat gtctcatgta
     7621 ttgggtggag ttgtaagaaa aggtaataaa caagaaaaag aatatggaaa aacagctata
     7681 acttatggaa aatcatcatt atttgaagga ataactacaa atagtgtatg gatgagtcat
     7741 acagatttaa tagaaaaagt tccagaagga tttactatag ttgcaaatac taatgattgt
     7801 ccagtagcag ctatggaaaa tgtagaacga aacctatatg gagttcaatt ccatccagag
     7861 gtggaacact gtttggaagg ggataagata cttacaaact tcttatataa tatttgtaaa
     7921 gtaaaaggtg actggactac agattcattc atagaagata aaataaaaga attaaaagaa
     7981 aaaataggcg ataaaaaagc tttatgtgct ttaagtggag gagttgattc ttctgttgct
     8041 gcagttctta ttcataaagc aattggggac aacttaactt gtatatttgt tgaccatggt
     8101 ttacttagaa aaaatgaagg aaatgatgta gaaagaatat ttagagagaa atttgatata
     8161 aatttaataa gagttaatgc agaagataga ttcttatcta aattaaaagg agtttctgaa
     8221 ccagaagcta agagaaaaat aataggtgaa gaatttataa gagtatttga agaagaatca
     8281 aataaattag gaaaaatgga tttcttagta caaggaacaa tctatccaga tgttatagaa
     8341 agtggacatg gaaatgctgc tactataaag tctcatcata atgttggtgg aatcccagaa
     8401 gatgtagact tccaagaaat tgtagaacca ttaagagagt tatttaagga tgaagttaga
     8461 aaaataggat tagagcttgg tatagaagaa ggattaatat ttagacatcc tttcccagga
     8521 ccaggtctag gaataagagt tataggtgat gtaactaaag aaaaatgtga tatattaaga
     8581 gaagctgatg ctgtttatat ggacgagctt agaaaagcag gtttatacag agaaatatgg
     8641 caagcttttg caacattacc agatgttaag actgttggag ttatgggtga tgaaagaaca
     8701 tatgcttatt tagttggttt aagagcagtt acttcttctg atggaatgac ttctgactgg
     8761 tataagatgc cttatgatgt attagaaaga atttctaata gaataataaa tgaagttgat
     8821 ggagtaaata gagtagttta tgatataact tctaaacctc ctggaactat tgaatgggaa
     8881 tagtaaataa aaaagtcgta agccttgtat tttcaaggtt tgcgactttt aaaaaaatct
     8941 ttgtgatact aaaatgatac tatatattta aattatctag tttttgggca acttcaagtt
     9001 gcttatttgg gtataaatgt gaatatgtat tccaagttgt ttctactttt tcatgcccca
     9061 atctttctgc tatagttaat atatttacat ccatatttac caataatgac gcatgagaat
     9121 gtctcaaatc atgcactcta attcttttta cattagataa cttacagcat ctatctagct
     9181 ctttagaaag ataactttta gcaaatttaa atattctttc attatctttt aagtcatata
     9241 gcttagatag ataatctttt atattattat ataagaaatg tgggataggg acaacacgtt
     9301 tacttttagg agttttagga gaagaaacaa tatcctctcc atttagtctt atgtagcttt
     9361 tttcgacgct tattttattt tcgaaaatat cttttggagt aagagctaac aactccccta
     9421 gtctaagacc tgtccaaaat aaaatttcaa atgctagtct aggttctgat ttcttttcaa
     9481 attcaataaa ttttttaaac tcttctaatg tccaaaagtt catttcatct gcgttttttt
     9541 taccgataga acctgccaaa tgagcaggat tagaaggtaa gttataatat ttaactgcat
     9601 aatttaatac agcaacaagc tggttgttta tcgttttaat atatgtttgg ctataatcac
     9661 tttttaataa ttcgttttgc catcttctta tatgtgttgc agtaatttca tttattttta
     9721 gacttttaaa aaaaggtaaa attctaaagt ttattaaata ctttttagtt tctaatgtag
     9781 ataattttaa tctagaagac atatcgtgca tgtattcttc tatgagactt tcaaaactca
     9841 tatcagtact cattttagat ttattcaaaa attctctttc aaactctaga gcttcttttt
     9901 tagttttaaa acctctctta attttctttt tcctatcccc atcgaagtct gtaaaataaa
     9961 agctagcata ccaacttttt ctttgttcgt ctttgtaagc aggcatttta gacaccccca
    10021 attatgtcat tttaatatta caataattat aacatgttag atatgctatc taaataattg
    10081 ttttattttc ctcttctttt tatttcttga agcttgtaat atttacacag ttctaagaag
    10141 tcttcttcta gtgctataga taagtctaat atcgtagata tacctatatc tttgtactct
    10201 tgattttcta gttttgatat ataacttctg ttacgtctca ttttttctgc taattctagt
    10261 tgtgtcattc ttttcttttt tcttaatttt ttcaacattt attaaaatcc accttttaat
    10321 tatttttatg acatttttat aattaatagt ttgtgtaatt tcttgtaaaa aatgttcctc
    10381 attagaacat tttttggtgg aaaaatgtgt taaaatgtaa gtaagaaaag cactttcaaa
    10441 gcactataaa aatagtgctg aaatagataa acaaataaaa gtaataagga ggaaagatag
    10501 attctagagg gaaatcatta tcatttttaa gaacgtatgt tcggttggtg ggatagaaaa
    10561 atactttaca ggggatggtt tatttgaatg agaatgaaaa tatgagttta tatgtcagta
    10621 agttaaaaga agtattgaaa aataattcag aagagtataa aaaaataaga gctaaaataa
    10681 atgaaattta taatctaaat gaaaagaaag aataaaaggg ctttagctct tttattcttt
    10741 cttagtatta actgctttat aataagcatt atctatcatt ttttttattg catttttatc
    10801 atctgaatct aaagatgcta atctatttat tagttcgtta acttcattat cttcttttga
    10861 gttaactttt tttaataatt catcatcttg ttgagtgtta ggttgtattt tacctaattt
    10921 agttaatagc tcctttaaag ttaaatttaa tccaaaactc attttttcaa gcatatctaa
    10981 agtaggttca acagctttac cattccttgg gtctctgttt ttttctatct tatctatata
    11041 tgtatggctc acaccacaaa gattagaaaa ttctctaaga gataagttat gttcacttct
    11101 atattcttta ataatttctg ctaatgtttg cataatttca cacctcatct aagtaatagt
    11161 tgacttaatt atatcagaaa aatgtaaact attgttaaca aaaataaaaa tttagtaaaa
    11221 aataattgac aagagtaaaa aaaagacgta tactatgatt aacaaaaagg ttataaataa
    11281 agttaggagg gattaatata aaaaataatt tacaatatat tagaaaagaa tctagaatat
    11341 cacaaaaaaa attcgctgat aagataggta tatcaagacc gtatttatct agaatagaaa
    11401 acggtaaggt taatccgagt ttagaaatag cgcataaaat ctcgctcgaa acagggaaaa
    11461 caataaatga aatttttttt gattttactg taaatcatag taaactataa ggttttaatt
    11521 gtaccttgaa aactaaatat aaaatatttt aaaggagcaa gtatatgaaa aataaagaaa
    11581 aagaaataat cattagagga attttaatag gaatttttta ttttttagga attgtattta
    11641 gtaatacttt ttttaaataa taaatagaag gggtaggtga aataccaact ccccaaatca
    11701 aaataacact ttggaagtta aatatagaat attcaaaaga ggtgattaga tggaaataga
    11761 gcaaacaaca atacgcctgc taaaaagcag acgaaagttg aatattaatt tctattttgg
    11821 ttaggcgaaa gacctaacaa aaaatctgta gatacattaa gtttgttaga aattaatatt
    11881 aaagtttcta tatttggctc tcttgaaccc gattcataat attgatatgc acgttctgag
    11941 ataccaaaca aactagcaaa ttgcttttga gtcatattca tttgctttct tactagctta
    12001 atattatctt tgaatttagt cataactaca cgctccaata aaaaaataaa taaatttctt
    12061 gacacgaaca atattagcgt gtaatatata aaacatagca cgaacaatat tggcgtgtta
    12121 aataaaaagg agagggtgaa aataaataac aatttaaaac tacaacgtga aaaagttggc
    12181 ttaacgcaat tagaggttgc tcaaaaagcc aaaataacag agagaagcta tcaatattat
    12241 gaagctggcg aacgtctccc aaacattcgt acagctttaa agatagctag aattttaaat
    12301 actaattgtg aaaaactctt taatgaataa tagcataaaa ggactcagat tacaagaagg
    12361 gagctttaga tatgaataat ttgcaactta acaataaaaa tacaataaca acattagaaa
    12421 ttgctgatat gttagaaatt aaccattggg aagtattgag aaaattagaa ggcacagaaa
    12481 aaacaaaagg aattattgat attcttaacg acaacaattt tgttgtggtt gattacttta
    12541 taaaatcagc ttatttagat ttaaaaaatg aaaatagaaa atgttacaat gtaacgaaat
    12601 taggctgtga ctttttagca aataaattta ctggagaaaa aggaattatt tttacagcta
    12661 gatatgtaaa aagatttaat aaaatggagc aagagttaaa agaacaacaa cctaaattac
    12721 caactacata taaagaagca ttgcaacagt tattaataga agttgaagaa aaagagcaat
    12781 tacaattaga gaaccaggca atgaaaccaa aagcagatta ctttgatgct ttagtagaaa
    12841 gaaacttgtt aactaatata agagatacag caaaagaact tggagttaaa gaaaaagtat
    12901 ttgtatcatg gttaatagaa aagaaatatt gttatagaga ttcaaaagat aagttacaac
    12961 catatgcaaa tagaatgcaa tacttcgaga aaaaggaatt tacaaatgag tatggttatt
    13021 caggtgtaca aactttgatt aacccaagag gtagggaagc tatcagatta ttgcttataa
    13081 aggatggatt aattaaagaa aaagaaaagg gatgccaaat aactttatta ggttagaact
    13141 ttgaaaacta aatacagaat attttgaaag taggtgtatt gtatggcaaa agcagtagct
    13201 aaagaacaat tgttttatag ggcaaaagat atagctaaat ttttagatat atgcgaagca
    13261 actgcataca aaataattgc agaattaaat gaagaattag aaaaagaagg ttttaagact
    13321 ttttctggca gggtatcagt tgcttatttt aaagaaagat attgttataa gccaagaaag
    13381 ggggtgattt agttgaatgt aaaggtacta atagcttata tacagttttg caatgataag
    13441 caaataaaag caagttttga aggtcttaga aaatacaaca gagatataga gttagttaac
    13501 ttatatttac caacacattt aaaaataaag taggaggttt aattgtatat ggtatttaat
    13561 ttagaggagt tcaaagtagg aaatgcagta agaataagtt gtgaaagatt tggttttgaa
    13621 attgattgta ttgtagtagt agcaactgag aaggaactaa atttagctta ctttgataaa
    13681 gaaagaggtt gtatggagta tcaagcattg ataccagaag accttagata tgacgattat
    13741 attcttgaaa gattaggtta gggggtgtat tttaatggaa acagctatat ctattgcaaa
    13801 aggtcaaata gaaggagcga atgagagtat aaaggaatta aaatcaaaag aaaattacga
    13861 taaagaaagt ttaagatggt gggaaggtgt taagcaagct agtgaaaata tactagagtt
    13921 tttagaaata gaaaataagg cataagaaaa gagccattac gattggctca attcaaaaac
    13981 ataataaaat ttaattagct atattatagc acaaggggga actaaaatga aagcaatttt
    14041 attaaaaggt ttagaaatag aaaatttcaa aggaataaaa gaacttcgca tagattttaa
    14101 caacataact aatatatttg gagaaaatgc aacaggaaaa acaagcatat ttgatgcttt
    14161 tacgtgggta atgtttgaca aggatagtaa gaatagaagt gtattcgaga taaagccttt
    14221 agataagcaa aataaagtca ttagagggct tgtaacaact gttacagcag tactggaagt
    14281 taataataaa gagattaaat taactaagaa atacgaagaa aaatggacta gaaaaagagg
    14341 ggaatcagaa gcaactttta ctaagaatga aacaacatat atgataaatg atactcctat
    14401 taaaaaatct gaatatgtaa aagagatagc tgaaatagct gacgaggaac agtttaaatt
    14461 acttactaat ccatactttt tttcaaatga gctgaactgg aaaaaggcta gagaagtaat
    14521 tttagagata tgtggagata taacaataga acagattata gagtcaaata aagacttagt
    14581 tttacttact acagagtttg aaaaggaaaa taacatagat aagattatta aaaatagaaa
    14641 agctagtaaa aataacttat ctaaggaaaa agaagaaata ccagttcgta taaacgaatg
    14701 taacaaaggt atgtacaata tagattttga ggaaatagag gttcaattaa aagctaagaa
    14761 gtctgattta gaagctattg aggataatct tttaaatggt acaaagacaa atgaacagat
    14821 tttaaaagat aaagaaaaga tatttgaact aaagcaagag acacaaagta ttaaacaatc
    14881 agcgagtaaa aaaggaaata agaaaaggaa tgagctgtta aaagaaaagg atgagttgca
    14941 atataatatt aaaaatttaa gaaataatct tgtttattta gaaagggata gtgagttaaa
    15001 agaaactttg agaaaaagag cgattgaaaa aacaacaaat ttaagagata aatggactaa
    15061 aaagagtcag gaaacattag atttaagcgt tattcagact gagtgtccaa cttgcaaaag
    15121 acctcttgac ttagaagata tagaagaaaa gaaaaaggaa atgttagata attttaatct
    15181 aaataaagct aaagaactaa aagaaatagt agaactaggg aaatctaaaa atgatgatgt
    15241 agaattattt aatacagaaa ttgaaagatt aaaagtagat ataaataaga ctttagaaga
    15301 gatacaagaa aaagcagtat tattagataa aataaaaaaa gaattagaaa gtacaaaatc
    15361 tacagagata tattcagcag atgaggaaaa aagattaaca gaaattagtg tagaaataaa
    15421 agagctagaa gaaaaaataa acaataaaga taatgataaa aacattgatg aactaaaaga
    15481 aagtaagaaa aaactagctg ttgaaattga gttacttaat aaagaactag ctaaaagaga
    15541 tattaacaaa ggactattag atagaaaaga gcagttatta gaaaaagaaa aagagctagg
    15601 tatagaacta gctcatcaag aaaaaatact caacttatgc gaattattta taaaaactaa
    15661 agttagttta ttagaaagta atataagtag taagtttaag aatgtaacat ttaaattatt
    15721 caaagagcaa ataaatggag gtattgaaga aacttgtgag gcattagtgg atggagtacc
    15781 attttcaaat gttaatacag caggacaaat aaatggagga ctagatataa taaatacttt
    15841 atctaatcat tttggagtta aaatgccaat atttattgat aacagggaga gtgtgaatga
    15901 tttgattgat attgatagtc aagtgataaa tttgattgta agtaatgata atccattaaa
    15961 aataaaagga gtgaattaat atggcaaatg aaatacaaag acaagtaagc gttaaaaatc
    16021 tattatctac agaagcgtat aagaaaagat ttaaagaggt attaaaagat aaggctaata
    16081 catttatggc atcagtggtg aatgtatcta acttgccaag cctaaaggat gccgaaccta
    16141 attcgatttt aaaatctgcc atggttgcag caacattaga tttaccaata gacccaaatt
    16201 taggcttctc ttatctagta ccttttgtaa acaaaggagt taaagaagcg caatttcaaa
    16261 taggatacaa agggtttata caactagcta tgaggactgg acagtataaa acaattaatg
    16321 caatagaaat ctatgagaat gagattaaaa gtgttaacag actaactgga gaaatagaat
    16381 ttaatgaaaa taaagacgag atagacaatg agatagtcgt tggatatata gcatatttta
    16441 aactgctaaa tgggtttgaa aaaactttat atatgagtaa agaagatatg gaaaagtatg
    16501 ctaaaagata tagccagaca tacaaaagca ataaggatta tgttgtaaaa tcaagtcttt
    16561 ggacaactga ttttgatgct atggcagtta aaacggtact taaaaggttg ttatctaaat
    16621 acgggatatt aagtatagaa atgcagaaag ctttagagac tgaccaagca gttataaagg
    16681 atgataattc agttgaatat gtagacagac aagtagaaga agaaatagaa gaaaatgcta
    16741 ataaaaagac tatagatatg acaacagaag aaaaggaaaa agctattgaa attaaagaat
    16801 ctaagcccga agaagcaacc caagttgaat tggatacacc accattttaa ggatgaaaat
    16861 caaagtatta gggagcagta gcagaggtaa ttgctacttg ctccaactga aaaatgagac
    16921 attaatttta gagtgtggag tcagttacaa agagatatta aaaggcttag atttcagttt
    16981 agaaaatgtt gtaggatgtt tggtcacaca tgaacataaa gaccactcta aagctatcac
    17041 agagcttaca aataatggaa tagatgtata ttctagcaag ggtacattag aagctttaaa
    17101 aatagaaaat catagaacta agattataga aagcgagaaa ttattcaaga taggtaactt
    17161 taagatagtg ccatttaata ctaagcatga tgcggtagag ccattaggat ttttaataaa
    17221 tcatagtagt tttggtaacc tattatttat aactgatagt tattattgtg aatacaactt
    17281 taataattta aatcacatca tgattgagtg taactatagt aaagatttat tagataacaa
    17341 caaagataag atttatttga gaaatagaat agtcaaaagt cattttgaat taagtaatgt
    17401 gattaatttt ctaaaagtaa atgatttaag taatataaaa acaattacat tgcttcatct
    17461 aagtgaagat aacagtgata aagatttatt tataagagag atagaaaaga atgtgggagt
    17521 accagtaata gtagctgaaa aaggattaga aatttattta gactagaggt gataaagtgg
    17581 caaaatatag aattttacaa gctaactttt gggatgatgg atttgtatta gatttaactc
    17641 ctgaagaaaa gtacttttat aactatcttt taactaatgg tagagcaagt caatgtgggt
    17701 gttatgaatt accctataaa attatggaaa tgcaaacagg atataacagg gaaactgtag
    17761 agaagttaat taaaaggttt atagagtatg gaaaaataaa atatgactct actactaaag
    17821 agatattaat aattaattgg agtaaacata atttttctaa aagtccaaaa gtacgtactt
    17881 gtatcttaaa agaggttgaa tcaattaaaa ataaagaatt tcagcagtat atgtatagag
    17941 tatgtataga ctatggatac cctatcgata cagtatctat agactatggg gaaaaagaaa
    18001 aagaaaaaca aaaagaaaaa gaaaaacaaa aagaaaaaga aaaacaaaaa gaaaaagtag
    18061 aaccgttaat ttgtgaagaa caggaaaaaa atgagttaaa agaatttaag aagctatatg
    18121 aagaaaatat aggagtggta tatccagtta cagcagaatg gttaatagaa atttctagtg
    18181 atgtagatat aagattattt aaatctgcta tagagatatg tgctgaaaag atgaatatga
    18241 atatagcata cttaaaaggt atccttaaaa agtggaagga tgcgaatata actacatatg
    18301 aacaactaga atcatataga ttacagcaag aaaataagaa agcaaaaaaa gtagttaatg
    18361 gccaactaag taaaaataag tttgccaact ttgaacaaac atttactaag tatacagaga
    18421 atgagcttga taacataatt aagaaaagtc aagatgctaa gttcaaataa aattaaactt
    18481 ctaggaagta aatatcaata tattgcttcc tagaaagggg gtagaatatg ggtaaaattt
    18541 ggatggatgc aggaacattt ttggaaacta aagatatagg agatattgaa tgtaatctaa
    18601 gagaaatgat aaataaaaat aaacaaaaaa atttaattgg tagaataaat tccaaaggac
    18661 aaggaagaaa aagtaagaaa gtagagtgta ctaacatcat tactggagag agtaaaatat
    18721 ttgtcagtgc tgtagaagca agtgaatatt tatatttcac ggaacttcat attactcgtc
    18781 tagcaagaac aggaaagact actaaaaatg gttggaaagt tagatatatt gaagaggtgt
    18841 caaatggtat tagcaaatgt ggaacaagta attaagttag ctgaaaagat attaagtaag
    18901 aaaaagtgtt ctgttaataa agctattgat atagctataa aaatattaaa tagatacgaa
    18961 tatgagggga tgattaaatg agtctaattg aatatagagg ttatgatttt gaaaataaaa
    19021 agtggattta ttctaaaaca ataatgtgga gtaatgcagt agactgttta ttaatgctga
    19081 aagaagattt taaatggcga aaagtttgta atgttggaat atgttctgaa gaatgggctg
    19141 gaaataatca agaaattttt gaaggggata tattaaaaga aaattataat cctcacaata
    19201 gaagttcata tggaattgta aaaagagatt ttaatagtat taagttatat ttggagtggc
    19261 attatttaaa gaagtttgaa ggagaatgga tagagattat agataaaaca gaaatatatc
    19321 atagtagagg ttacaaagta attggtaatg aatatgagaa cttagaggaa gttaggaaag
    19381 agtttttaga acgcaaggag atgttggaaa atgaacgtct tagctagttt aatacttata
    19441 gtaggaagtt ttatagctgg tagggtttat gagtatagat tgaatctaaa agagtttgaa
    19501 aattatgata atataggagg ttttaagaat gaatgataga ttagaaatga taaatgcttc
    19561 tgtaaattat atacagatga tatgtgaaag ttcaaatata gctattatag cagagcatga
    19621 ccgagttaga atattggatt tagaaactaa agaaaagtat gacctattaa gaagtgaggg
    19681 ggattaaaaa atgagtaaag ttatacaatg tgatttctgt aaggaaatat ttgaaaaata
    19741 taatggagaa tgtattgagc tatataaaaa ggattgtagc aaaggggtgc ttgggataga
    19801 taaacacata tgcccaactt gttatgaaaa attcattgaa ggaaaaatag agaaagtaga
    19861 aaatgctaaa agatttaagg ataaattaat agacttcttg gttgagcatg aggtttgtga
    19921 ctgttgtgct tgcgactgtg tgtttgattc taatgacgaa aaaaaatgca aggcaggaat
    19981 tagagagtgg gttgaaagtg aggtagaaga ataatatggc aaaattaata gttagcatac
    20041 ctttaactaa atatttaaaa gatataacta aagaatgggg agaaacttat ataactaaaa
    20101 catatggtgg gcatgtctat ttaagtgatg aagctccagg agaagtactt aaaaaagaag
    20161 atgatttaaa ttatatagag tttaacgatt ctgatattgt catgagatta cctaaagaag
    20221 tacatcaaca tataaatttg aaaaaaggtt gcaacaagaa tcttaaagat gtattaaaag
    20281 aaataaaaaa gatagaagag aaaacaaata tatagaaaat atctaattaa aacagtttag
    20341 agagttgcaa aatatctttt agtataaatt tattgttgaa gtgttttgtg actctcaaaa
    20401 atgaaaataa ggaggagcta tattgcttac atttttagat ttattcgcag ggataggtgg
    20461 ttttaggcta ggaatggaaa aagcaggaca taaatgtttg ggacattgcg aatatgataa
    20521 attcgcaaat ttaagttata atgccatgca caaaccgaag gaggatgaat ggtttgaaag
    20581 agatattaga gaaattagaa cagaaaatat cccaagagca gatgtctggt gttttggatt
    20641 cccatgtcaa gacatttctg ttgcaggtaa acaatttgga tttaaaggaa gacgttcaag
    20701 tttatttttc gcagttacaa aacttattag agaactcaaa gaagaagata gacccaagta
    20761 tttacttatt gaaaacgtta aaaatctact tagtgttaat ggaggatttg atttcctcaa
    20821 agttctcatt gaactggatg aaatcggcta tgatgcagag tggcaagttc ttaactctaa
    20881 aaacttcgga gtaccccaaa atagagaacg aatattcgtt gttggacatt ttagaggacg
    20941 aagtacacga aaagtatttc ctatcgaaag aaaaagtaga aaaaatcttg aacaactaaa
    21001 taatccaact catagtacaa gtggagtttt agtcaatgca gttttaacac ccgatagggt
    21061 aaacaaaaga caaaatggtc gtagaattaa agaaagcgga gaaccaatgt tcacactaac
    21121 agctcaagat aaacatggaa ttttgaaaaa tggagatata agaaggttaa caccaaagga
    21181 atgctttagg ttgcaaggat ttccggataa atattacgaa agagcagcaa gtgtatgctc
    21241 agatagtcaa ctgtacaaac aagcgggaaa tgctgttact gcaaatgttg tatatgaaat
    21301 agcaaaaaga atgggctaag agttgcaaaa tgtcttttag tatgagtatt gttgaagtgt
    21361 tttgtaactc tcaaaaatga aaataagggg tgaataaatg tcaaagtatg tgcttagatg
    21421 gcaaaaaggg ttattgttgg atgaacgtaa gataaattat tcatgtggaa gtaaagaaat
    21481 gctaaaacaa aaagcagaat tattagctaa agatgacaag atattgcttg taacaataga
    21541 taaagttgaa gaagttataa aagatactag aagtcaaaaa atggctgaat attattgtga
    21601 tggaggaatt gaaatatgat aatacacaaa tttataatac atgttttaga taagaatagc
    21661 gatacaccaa tactaaatga ttttgagggt agggttagtc aagatattga agctttcttt
    21721 caaaagaaaa taagcaaagt atcaagagat aatgacatca gaacagtagt atttaatgac
    21781 tatagtaaca atctaattaa gaagtgttgt gaacaaatta tttatgatga aagttcattt
    21841 ttaaataact ctaaagagat tgcagcttat ttatttgatg ttatgaaatt gaatgctata
    21901 ttagaatctt gcgacttagc aatttgctta tactctcaaa aagatgaaaa gaaagttgct
    21961 atattaaagc ttgattacaa taattcgtat actcattcta ttagctttga agaggataaa
    22021 tttaatatac agatgtctaa gaatgaaatt aatatacaag agactaagac ggttaaaatt
    22081 gctgctttgg ttggattgag tggaatgaat gacgaatatc atctaaaagt attggataag
    22141 gatgcagaga aggaagaagc taattctaag tttgttacag agtttctaaa tgctactaaa
    22201 gtgaaagatg acaagtatag gactaaaaag tttaaagata cagttgaaaa ttggataact
    22261 aatgttcttg gaaatgatat aaaacaagct gaggacataa gaagtatatt aaattatact
    22321 ttgaaagaaa agcatgaaat tgatataaaa gattttgttg ataaatcaat taaagatgat
    22381 gagttaaaaa atagttttaa agaacatatg gaagaaaagg gtcttgatga aagttttagc
    22441 atagataaaa aatgggttga aaaaaagctt aaaaagagaa atataaaaac tgacaatggt
    22501 tttgaaataa aaggtaactt aactgatttt gaggacccaa tgaaatatac agtaagacaa
    22561 aatcaaaatg ggtctataga tataattatt aagaatgtta atttctataa tgaaaaataa
    22621 gggggctaca atggaaaata aagataattt tgtattaaat aagcttggac cagcaagtaa
    22681 agtaatgaaa aaagttgaaa tagatgaaaa agaaattaag agttatctaa aagaactaaa
    22741 agaatgtgaa gaagtaaaag tttttattat tagaaaagat ggaattgaaa ttccaatagt
    22801 tttcaaagat ggaaatatga acgaatggtt aagaaaagaa attgagataa gttttgatag
    22861 atttaaggat gaaattgctc aagttaaaaa agcattgatt aaagttacag gagagaatta
    22921 agaagttaga aggtgctcat atgactaata aagaaatgtg caagtcaaat aatcttgatg
    22981 aaagagaagt gtgtaaggaa tttggaaaag agatttgtgg tagttgtata aatgataggg
    23041 tagattgcga aagcaaagat tgtgatatag catatgaaaa ttggctagag aagaatacag
    23101 aaagataatt ataaaaataa agtcaaggta agtttgtgaa tgaaactaga atgttataga
    23161 cttactttga cttataaaaa aggagtgtat taaatggcta atatatattg cgaaaattat
    23221 aattgtaaaa actactttga agatatgtgt atgcttgaaa gaattgaaat taataacctg
    23281 aaagtgtgtg aaagttacat tgaaggtaaa aatgagctat ataaattaga aaacggatat
    23341 actatacatc ctaaagattt gaaaatggtg aaaagtaaag attattctgt tgaagttact
    23401 catattccaa ctggtattac agtaaaatgc cgttctacaa atagtatttt aaaaaataaa
    23461 aataagtgtt tggaagttct agaagaagaa ttaataaaaa taaactctca cttagagcta
    23521 gaagatttaa actaaatagg aagtgagctt atgaaacgaa gaagatgcag ttggtgtggt
    23581 aagctatttt atcttaagga aaaatctaag gatgtttatt gttgtaaaga atgtaggaag
    23641 aaggctaaga aggtgaaaaa atgaaagttt ttcttgtaat agatggagag ccagttggca
    23701 aggaaagacc aagaatgaat acttacgcta aaaggaccta tacacctaat aagactaaga
    23761 attatgagga cctaataaaa tggctatatc aatctaaagt taaatattac tttgaaggtt
    23821 atataaaaat gactttaaga tgttattatt ctatagctaa aagtaacagt aaaaaggtta
    23881 aggagcagaa aagaaataat gtgttaagac ctagtaaaaa gcctgacatt gataatgtca
    23941 ttaaagtagt agctgattca ctcaatgaga tagcttataa ggatgataca cagattgttg
    24001 aggttgtagc tagtaaatat tacagtgata aaccaagagt tgaggttata ttagaagatg
    24061 ttatttaacc aacggaaaaa tccgttcgtt agattaggta ctcagttttt cataaaaatg
    24121 tgaaaaagct gaatagagaa tatatcaaat ggtaaaggag agataaatta tgaatgaaaa
    24181 tataaataaa gaaataacag tacttggaac tttagaaatc gagggaatga aatttcataa
    24241 cattgagggt ggatttggag aacataagaa agcaatgcta gtaaaagata tagctgagat
    24301 acataataga gaacttaaac atataaatga gctaattaat aataatataa agagatttaa
    24361 aacaaatata gatattatag atttaaaagt gagtcgttct gagcgactag gtgatttaaa
    24421 ggctaatcct tttgaaggat taggttacga ggatgttgga tatagtaaac aatcttttaa
    24481 tcagtcaaga aatatttact tgttatctga aagaggttat tcaaaactac taaagatatt
    24541 agaagatgat aaggcttggg aacaatacga gaaaatagtt gatggatatt tctctatgag
    24601 aaaagagtta aataaccctc ttttaagtgc atcgaaggag ttacaggcta tatttatgct
    24661 agataagaaa caagaagtct tagaaactaa aatagagaat gttaatgaga agttagagaa
    24721 ctttatggat gatgcaccat tattcaatat cgagtgtgag tgtattgtta aagaggttaa
    24781 gagagtagca acaaaatcac ttggtggaca tggaagtaag gcttataaaa ataaatcttt
    24841 aagaggtaaa gtttatagtg atatatacca tcagattaaa cgagaatttg gagtagatag
    24901 ttataaggct ataaagcgtt gtcagttaga taaagtatta gagattgtaa ataattataa
    24961 gttacctata gtgtttgaag aagaaataag acttttgaat agtcaattat caattgtgag
    25021 ttaagacagg aatagatttt tctcctttaa aggggaaaac ctgcaatagt taattaaaag
    25081 agaaaaggag tgctttcaca ctccacttgt caaaaatata aaacttttat atacaagatt
    25141 attataacat aaataattga taggagtgtg tgagtatgtc taaaactaaa aaagagtttt
    25201 ttaatgcaac taagaaacaa ctttctaatt ataaacaatt aagtgcaaat ataataaaat
    25261 taaaaaatga aatacaaatg ttgaaagata attcggttgg agatttaatg aaaggtataa
    25321 gttatgatag tgtcaaaaca ggaaaaacaa acaaaactag taacatgatt gaggatgcta
    25381 ttgttaatgt atcagactta ataacagaaa aggaaataga gttatatgaa gcagaaataa
    25441 ttaaatccac aatagattta gctataagaa acttaaaacc tatacacaga caaattattg
    25501 aacttaaata tatagatggt ctaatgtggc aagaaatggt tgatatagta catttagaag
    25561 aaagacaatt aagtgtaaga gctagtcaag ctattagctc aatatcaata gcattatttg
    25621 ggaagaaagc attaatagag caagaaccac tttttgaatt gttagattac aaactaaatt
    25681 aaaaaagtaa gagtaatttt gagtgctgaa aatgtgcagg tttttttgtt ttagacatga
    25741 gataatagta ttgtggaaat gaatatttct ctctcaaaac taaatatata tgtgggctag
    25801 gtaaagggat tcacctagct tatatgaaca gactaggcag ggcgtgagga cgctgttagt
    25861 tcaattctaa ctatgttcaa tctttagttt ttctatttca attaatctac ggatacacta
    25921 aaaaatagta tttgaattga gattaaaatc tcatacagtt ttgtatctta attcagagtc
    25981 taaaccgagt ggggcttggt aacctcactc accatgcagg tactggtgtt taatctaagt
    26041 tcgattctta gaacttgcga cataatatat gtatctccct atttaaaaag gctaagtgag
    26101 ggtaagctta gtcttttaat ttaaaaaaaa aagaaatttt tattgtcata atactatttg
    26161 cttaggtata ttataatgtg catacttaaa attaaatact tagcaagcat ttgaattaat
    26221 atacataaaa tatatgacat aattttttat agtgtaagtt atttaaatta atataaataa
    26281 cagtaatttt attatagaaa atgtatatat tgtgaataat aataataata aaatcttgta
    26341 caaaatgcca actgataatt cctcgaaatg tattgtgtat ttaacgttac gattgtataa
    26401 ttaacttata atagtgatat ggaaggtggt acttatggct acaaaaagta ttttaaaaaa
    26461 tgtagatgta agaaaaaagg catttggaag aaatctagta tcagctctag aaaatgctaa
    26521 aaataaacaa gaaaaagaag ttgtattaag taaaaaatgt tcagaagtac caaaagataa
    26581 aataaaggat atattcggga gattttaatg agtggctatt taattgtaaa cttaagtaat
    26641 atgctgggag aactggagga agaagaagtt aaaaaaattc tctccagttt ttcttgtcct
    26701 cttaataaag atgtagaaga ctttttaaaa aacaaagcta ttgaattttc taaacagggt
    26761 ttagctagta cacatttagt attaacttct tataaaggca agcctgttat agttggatat
    26821 ttcactctag ctaataagta ttttacaata aaaagaaaaa cattaacaaa ctctttagct
    26881 agaaaagtag taaagtttgg acaatataat gaagaactaa gaagatatat tattggagca
    26941 cctttgatag gacaaatagg aaaaaattat tcaaataatt ataataaatt aattaaaggt
    27001 gatgaacttc taaaaattgc atgtgacaag ataaaagcag tgcagttaga tatgggtggg
    27061 aaaatagtat atcttgaatg tgaagacaaa cctaagttaa ttgaatttta taaggataat
    27121 ggatttgtag attttggtaa aagaagtctt gataaagatg aaacagattc attggatggg
    27181 gactatctag tccaaatgtt aaaatatcta aaaaaataaa agtacataaa atctaaaatg
    27241 actatcttga tggatggtct ttttttatac aataaattaa aaggagaatt atagaatgaa
    27301 aaagataact aaacttatat tatgttcttt gctagtaatc agtatagcga gtccattaca
    27361 agttgaagct aaaactactc atcattccag ttcgcatgtt tctattcata agagtagtac
    27421 aaaatctaaa agtagtagac ctaaaattac taaaactaaa aaagctacta aaacatatag
    27481 aactaacaaa tctatcaaaa agaaaataaa acttaaaaaa caagtaaaca aaaaaactca
    27541 agttccaaat aaacaagctg ctagaaaaga caaaaaaaca actacatata attattacaa
    27601 tagctataac tcaaatagat actatactac ttcaagtagc gggttaagtt tctgggattg
    27661 ctatatgtta ggtcatttat tcaataacaa caataaagtt tcagagcaag atatagctag
    27721 agagttgcaa aaacaaggtt atagtaaaca ggaaactgat aatatattaa gaaaagcaaa
    27781 tcaaaatcaa gctaaaaaag aagaaaagaa aaaaagagtg atgatgttaa tattctctgt
    27841 attaggagca ttgttcatta taggtttagg gctaataata tttatcaaaa gggaatcaaa
    27901 aggttgcaat aaatcaatgt aatttaatta gatacataga ctctaacaag agttcttttt
    27961 tattcccaaa acgacaaaca aacgaggtgg tggtatgaat gaaaaggcag atttagccca
    28021 tgaagattac ttaaaagggc ttaagtacaa ggaaatagct gaaaagcata atgtaagttt
    28081 atcgactgta aaatcatggg caactagata ctggaaacaa aaaggttgca accaatcaaa
    28141 aaaagttgca accaaaaaga gaggtgcacc cataggtaat aaaaatgcta ctggtccacc
    28201 aggtaataaa aatgctgaaa agtttggttt cttctcaaag tatctacctg aagaaactag
    28261 ggaattgatg caagaaatat ctataaaaga taaattcgat attctttggg aacagataac
    28321 aattcaatat gcagcaataa taagagcaca aaagataatg tatgttaaag acaaggaaga
    28381 aatgattaaa gaattaaaga aacatgaaag tacagaaaat ggagagaaga tagagtatga
    28441 atttcaattt gcatgggata ggcaagcatc ttttcttaat gcacagagta gagctatgag
    28501 tgaattaaga agtttaatta aacagtatga tgaaatgatt cataaggatt ggaatttggc
    28561 tacagaggag cagaaaacaa gagttgagaa gttgaaatgt gaagttgata acctaagtaa
    28621 agatgacatt ggagatgatg agttgaaaat aagtgtagat tatggtgata gaaatgatag
    28681 ttagagtaaa ttttaatcca gatttcaagg aagccaattt tactaaaaaa agatacagag
    28741 caatgaaagg ttcagcaggg agtggaaaat ctgttaatgt agcacaagac tatatactaa
    28801 agttaggaga taagaagtat caaggagcta atctattagt agttagaaag tcagaagcta
    28861 cacataagta ttcaacgtat gcagagctta caggagctat aaatcgtatt tatggtaaac
    28921 aagctgataa gtattggaaa actactttaa atcctttaga aattaagagt aaagttactg
    28981 gtaactctat aattttcaga ggagttaatg atgcaaaaca aagagaaaaa ttaaaatcaa
    29041 ttaacttctc gaaaggaaaa ttaacatggg tttggtgtga agaagctaca gaacttatgg
    29101 aaagtgacat agatatacta gacgaccgtt taagaggtat tttaactaat cctaacctat
    29161 actatcaaat gacatttaca tttaatccag tctcatctac tcattggata aaaagaaagt
    29221 attttgacta taaaaatgat gatatattta ctcatcatag tacttatcta caaaatagat
    29281 tcatagatga ggcttactac agaagaatgc aaatgagaaa agagcaagac cccgaagggt
    29341 acaaagtcta tggtcttgga gaatggggag aaactggtgg agcaatactt aaaaactatg
    29401 ttatacatga atttcctacg gaatttgaat actttgataa tatgagactg tcacaagact
    29461 ttggctttaa tcatgcaaat gtagtactca gaattggttt taaggatgga gagttatata
    29521 tatgtaatga aatatatgta catgaaatgg atacatctga aataataaag attgcaaaca
    29581 gtaaaggttt agaaaagaat atatttatgt actgtgatag tgctgaacca gatagaatta
    29641 agatgtggaa gagtgcagga tataaagcta aaggagttaa aaaaggacca ggaagtgtta
    29701 aagctcaaat agattatttg aaacaattaa gaatacatgt acatcctagt tgcactaata
    29761 ccataaaaga aatacaacaa tggaaatgga aacaagatga aagaactgga ttatatcttg
    29821 atgaaccagt tgagtttatg gatgatgcaa tggctgctct tagatattct atagataata
    29881 agcttaaaaa taatggaata agcttcttaa agtaaaggag gcgttaaata tttatataag
    29941 tgaaacagat ttaataaaag ttcagttaaa aaaagagagc acatttaacc tagtaaaagt
    30001 tatagagcat tatattttaa aacatagacc agagaaatat aaacaaggtg aagaatacta
    30061 ttatggcaat gcagatataa acaataagag aagatattat ctcttagatg gagctaaggt
    30121 tgatgatttt actaaagtta ataataaagc aattaacaac taccataagc ttttagttga
    30181 ccaaaaggta ggctatagtg tcggaaatcc catagtattt aatgcagatg atgataatct
    30241 cactaagctt ttaaatgact tactaggaga agagtttgac gatacaataa cagaactata
    30301 tctcaatgct agtaataaag gggttgaatg gttacatcca tatattaata gaaaaggtga
    30361 gtttaaatat gtaataattc cagctgaaga agcaattcct atttgggata gtaaaagaca
    30421 gagggaatta gttgcattta ttaggtttta ttatattgaa gatatagatg gaaataaaat
    30481 aaaaagagtt gagtactaca cagaaaatga cgtaacttac tttattgaaa gaggtaatag
    30541 ttttattcaa gaatttttat atgatgaata tggaaaaatg actgatatac aagaaggtca
    30601 ttttagaata aataacaaag aacagggatg gggtaaagtt ccatttatac cttttaaaaa
    30661 taatgaaaag tgtgtctcag atttaacttt ctataaatca ttaatagata tatatgacaa
    30721 taatatttct acactagcag ataacttaga tgaaatacaa gaggttattt atgtattaaa
    30781 agaatatcca ggaacaagtc tacaagagtt tatagataat ataagatact ataaatcaat
    30841 taaagtagat ggtggaggtg gagttgataa actagagata aatataccag ttgaagctaa
    30901 aaaggagctt cttgatagat tggaaaagaa tataattatc tttggtcaag gagttaatcc
    30961 agaatctcaa aacacaggtg acaaatcggg tgtagcactt aaatttttat attcactact
    31021 tgacttaaaa tgttctaaga ctgaaaagaa gtttaaaaaa gcaattagag agcttttatg
    31081 gtttgtgtgt gagtatttaa agataagtgg taataagagc tatgattata aaacagttca
    31141 aattactttt aatcactcta tgataataaa tgaagctgaa aagatagata tggcagctaa
    31201 atcaactgga attgtatcag atgaaactat tgtttctaac catccttggg tcgaggatgt
    31261 taatgacgaa cttgagagac ttaaaaaaca ggaagatact caaaaagagt atgatgattt
    31321 aattcctaat aatcaagatg gtgttataga tgaaacataa agattattgg aggaagagat
    31381 ttgaacaatt agaagaagct cagaataata aaagtataaa atattatctt gaattagaaa
    31441 aacaatataa actagcaatg tctaatatag aaaaagatat acttatatgg tataacagat
    31501 tcactgaaaa tgagggaata tctttattgg aagctaagaa actgctaaat acaagagaac
    31561 tagaagagtt taaatggagt gtagaagaat atattaaata tggtaaagaa aatgctataa
    31621 atcaaaagtg gatgaaagag ttagaaaatg ctagtgcaag agttcatata acaaggcttg
    31681 aagctttaaa actgcaaata cagcaacaag tagaagtttt atatggaaat gaacttgatg
    31741 gtattgataa actaatgaga gatatttata caagtggata ctatcataca gcttttaatg
    31801 ttcaacaagg agtaaacgtt ggttggagtt taatgagtct tgatactaac agaataaata
    31861 aagttatttc taagccttgg actagtgatg gattaaactt tagtgaaaga atttggggta
    31921 agcatagacc tgctttaatc aatgagttac atactaagct aactcaatca attattagag
    31981 gtgaaaatcc aaaagttttg gtaaatgaat tttctaagaa gtttaatgta tctaaatcac
    32041 aagctaagaa tttaataatg actgaatcag ctttctttgc atcagcttca agaaaagatt
    32101 gttttaatga tttagatgta gaaaagtatg agattattgc cacactagat ttaaaaacat
    32161 caaatatatg cagagagtta gatggaaaag tatttgatat gaaagattat caagttggaa
    32221 taacagctcc accatttcat tgtcattgca ggacaacaac agctccttgg ttcgaggatg
    32281 aagaaggtta tagagcagca agagatgaaa atgggaaaac atattatgtg ccatctggta
    32341 tgaaatataa agaatggtat gaaaagacat ttataactga taaaaaagat gatatactaa
    32401 gtaataagag ttggttaaaa gcagatttcc caactgaaaa gaaatttaaa aagcatgtag
    32461 aaaaacactt aaatgaatat ggaaatataa ctgctgaaga atatttatct actgcaagaa
    32521 atttgttatc agagcaatta agtaatgatg tagaaggatt tttaagtaaa gataactttt
    32581 tatttaaata tagaaagagt actaatgatt ttgctgttgg aagagctgat ggtaaaatat
    32641 caaccttatt taagccaaaa gaaggttata attactggct agaacaaata aaagaatata
    32701 aggaggttta gacatgaatt gtccagtatg tggtaaagat gtagatgtat ttgatatttg
    32761 tgataattgt aattggcaaa acagtggacc aaaagaaact aattacaaag gaccaaataa
    32821 aatgtcatta aaagaagcta aagaggctta tgaaaaaggt aaaaaagtaa tataaaagca
    32881 cttgctaagt tataaattag taggtgcttt tattatgtaa aaatttattg cgagggtgat
    32941 ttgaaatgct taaattatat ctatacttat tttatcaata attgtgtttt gtacagggct
    33001 ttatttattc aacatgaagg ttgatagtaa tgaggaatta attgaattac ttaaaagtaa
    33061 gaatatcaga agaagaaaaa aatataattt tattttccca gcgttatttc cactgcttaa
    33121 ttttatttta ggtgtgatac tgatactatt ttttttacta gttagcaatg aagatatgat
    33181 taaaaattta aagggggata aataatatgg ctaaatttaa aaagaaatca gaggaagtag
    33241 aagcttttaa atggatatta ggaagtccta atactcctat atggttttat caagcttttg
    33301 agaagggaac tatatggctt gatgaatctt taaactctgt gaatcgtaaa ggtgaagtaa
    33361 agaaaactat ctgtataaaa tataaaaatg gagttattag ggcaactaat ggagattgga
    33421 ttataaaaga tagtgaaggt aaaatttatt cttgtacatg tgatgaattt gaaaagtact
    33481 ataaggattt ggataatgaa acaaagattt ctaatggagg attggaatgt ttaagagaga
    33541 tagcattaaa agatgtgaat tttaaatttg aactcacagg aattaaggag gaaaaataaa
    33601 tgttttatct gttgttacaa gtaataagta tatgtttaag tattacagta tttatgtatg
    33661 ttacaggtaa tatagtcttt aaaatctatc ttaaaagttt aagaaaagaa tatgagtcta
    33721 atatacacga agtttctgat gaaattttaa agagaataag aaaagaatta aataaatcat
    33781 tagatgaaag tctttaagaa gttttttatt aggtagaaaa caaaaggagg tttctgttat
    33841 tgaaagaata tatgatttgg tttaaaagcg gcaatagcat atctggaata gtagacgaag
    33901 atgttgctga taagttaatg caagatttta tggaagctga ctcagattgt aaggacttga
    33961 aagtatattt agatgaagat ggaacaacag taatagattt atcacaaata gaagctatat
    34021 caataaataa ttgtaatgag aataataata ttggttttag taagtcctag atagggcttt
    34081 tttattttgt aaaaaatgaa aggagatatt taaaatggat tggttaaaag aattgctaga
    34141 aggaataaaa gtagaggata acaaaattga tgtagcttct cttcaaaaat ctatagaaaa
    34201 gaaaataaaa gagactacaa ttactaaaga agattataca aatcttgaaa cacaacttaa
    34261 tacagctaat gaaactatta aaaagtttga aggaggtatg acaaaagaag atgtagagaa
    34321 tctaaaaaca acttatgaaa ctgataagaa aactttggaa gaaacctaca aaaaagaaat
    34381 tgaagaaaag gactttaatt actggttaaa tgatgctttt aagtctatta aatgtaggga
    34441 tgaaatagcg ttaaaagctc atttagatat agaagcacta agaaatagta aagatagaca
    34501 aaaagctttt gaagagcaaa taaacccttt gaaacaggat aaagattatt tgtttaatgc
    34561 aacactagaa ggtgaagagc ctaaaataga tactataaca ccagggcaag agcctaagat
    34621 aaatgatttt ggttttaatt ttactggggt aagacctcat gaaaataata ataaatagga
    34681 ggaaataaaa tggcagcact aaattatgca aaagaatatt caaatgtttt agcacaagca
    34741 tatccttata ctttaaactt cggggatttg tatgcaacac caaataatgg aagatataga
    34801 tggactggtt ctaaaacaat agaaatacca actatatcta caactggaag agtagattca
    34861 aacagagata caatagcagt agctcaaaga aactatgata atgcttggga acctaaggta
    34921 ttaactaatc aaaggaaatg gtcaacgttg gttcatccag cagatataaa ccaaactaat
    34981 tatgtggctt caataggcaa tataacaaaa gtatataatg aggaacaaaa gtttccagag
    35041 atggatgctt actgtatatc taaaatatat gctgattgga ccgcattagg taacacagca
    35101 gatacaactg ttcttacaac aacaaacgta ttagaagtat ttgataagtt aatggaaaaa
    35161 atgacagaag ctagagtacc tgaaaatgga agaatattgt atgttactcc agtagtaaat
    35221 acacttatca aaaatgcaaa agagatacaa agaacagtaa acataaaaga tggtggaact
    35281 tctttaaata gacaaaccac agatattgat acagttaaaa taattaaagt tccatctaac
    35341 ctcatgaaaa ctgcatatga ttttacaact ggatggaaag taggagcagg agctaaacaa
    35401 atctttatgt ccttagttca cccaagtgca ataattacac ctgtttctta tcagttctct
    35461 aagttagacg aaccaacagc agttacagaa ggaaaatact tctactttga agaaagtttt
    35521 gaggatgtat ttatattaaa taaaaaagct gatgcaatac aatttgttgt tgaaggagct
    35581 ggagcataat ggcacaagta agaaaattaa atagaatatt aactatagaa gaatgtaaaa
    35641 tagatgattt cttagagatg ggatatgatt tgatagatga aactggtaag gcagtaaagt
    35701 atggcaagtc attaaatgta aaagatttaa tagctgaaaa taatatttta aggtcaaaag
    35761 tcgagtcttt agaagaagaa aataagcagc ttaaagagaa aaataagctt actaaaaagt
    35821 aggtgaaaat tgtggaaaat aatatgattg atgatataga aagaagactt caaggatttg
    35881 gatatgttct aaaggatgga gataaatggt taatagattt tgtaagagaa aaaatagaaa
    35941 atattattaa actagattgt aatataagtg aaattccaaa agagttacac aatatagaaa
    36001 tagatatgat agctggagag ttcttattta ccaagaaaaa tatggggcaa ttagatatag
    36061 aaagtattaa ctttgaagct gtagaaaagt ctatatcaga aggtgataca aaggtagatt
    36121 ttgctatagg aagtggctct caaacaccag aacaacgctt tgatagctta gtagcttatc
    36181 ttactactta tggtaagaat aatatattaa cctttaggtg cttaagatgg taagtaaaac
    36241 tagaaaagca atagaaatgt tatatagaga taaatgtact atagttgagt atcagccaat
    36301 taaagaccct gtaacaaaac gaactaacaa taaagaagtg attgtattag aaaatcaacc
    36361 atgtaaactt tcatataaaa atatagtttc tgctacagaa gggaaagtag ctaagctaga
    36421 gcaaactatt aaactcttta tatctccaga tatagaaatt aaagcaggtt caaaacttat
    36481 tataaatgat aaagagtatg taagaagtgg agaatcagct atatatccaa atcatcaaga
    36541 aataatactt gagttattta aggataaagc ataatggcta gatggggcag tgttgatttt
    36601 agagagttta aaagagtttg taaaaagatg gagaagctta caaagattga tttagataag
    36661 ttttgcaaag atgcagcaag agaattagca gcaagactct taggaaaagt aattagaagg
    36721 acaccagttg atacaggatt cttaagacaa ggatggaatg gagtggctta tgctaggtcg
    36781 cttcctgtgt ataaacaagg aaataattat attatagagg ttgttaatcc gactgaatat
    36841 gcaagttatg taaatttcgg gcatagaact aaagatggaa aaggttgggt taaaggacaa
    36901 catttcttaa caatttcaga gatggaacta caaagccaag ttgataagat tatagagaaa
    36961 aagttattaa tattacttaa aggagtattt gatgcttaat aatattatag atggaatatc
    37021 agtaaagtta gataaatcat ttggagaaaa atatacaatt tatagtgagg atgtagagca
    37081 aggtattaat gaaccttgtt tttttattgt tcctttaaat ccaagcaaga caccatatcc
    37141 aagcgggaga gaattaaaga aaaattcttt tgatgtacat tatttccctc gttcagaagc
    37201 taagaatttt gaaataaatg agatagctga gatgctactg gaggaattag agtatataga
    37261 aattgatgga gatttagtca gaggtacaaa tatgaatttt gaaattatag acaatgttct
    37321 tcacttcttt gttgattata actattttac tataaaaaat aatgatacca ataagatgga
    37381 tacagtagag ttattcggtg gtttgaagag aggtgataat tttgaataaa acattaagca
    37441 aagaagatga ctacaagttt actaaggagc aaatagttaa ttctaagaag tatgtaaata
    37501 gaaaagactt attaaatgca attttaaaag aaaatgagtt atattccttc tcagaggtag
    37561 aggaaataat aaataaattt atgaaaggag tgagctagat ggcgttaggt ggaggaacat
    37621 ttgtaacaca gaataaaata ttaccaggta gctatataaa ttttatctca gctaagaggg
    37681 caaccagttc attatcggat agaggtattg ttgcaatacc tttagagtta gattggggca
    37741 tagatgaaga cgtatttcaa gtaaccagtg atgattttga gaagtattca gtgaagtatt
    37801 tcggatatga ttatactcat gagaagctga aaggtttgag agatttattc aaaaatataa
    37861 ggttgggata tttttataaa ttaaataaag gcgttaaagc cagttgtact atagccacag
    37921 caaaatatag tggtatcaga ggaaatgact taaaagtaac agttacaaca aatatagatg
    37981 ataatgctaa gtttgatgtt gtaacacttt tagataataa gaaggtagat actcaaatag
    38041 ctaaagtgat tacagactta caagataatg actatatcac ttggaagaag gatgcaacac
    38101 tagaagcaag tgcagggctg gtatttactg gtggaactaa tggcgaagct gtgacaggag
    38161 cagagtacca agctttcttg gataaaatag aaagctatag ctttaatgct ttaggatgtt
    38221 tggctacaac aacagagatt aaaagtttat ttgtagaatt tacaaagaga atgagagata
    38281 aggtaggagc aaagtttcaa acagtactat ataagaaaag tgatgcagat tatgaaggtg
    38341 tagtgtctgt agaaaataag attaaagata aagatttagt tgaatctagc ttgatttatt
    38401 gggctactgg agctatagca ggatgcgata taaataaatc taatactaat aaaaagtatg
    38461 atggtgagtt tgatgttggt gtaaattaca ctcaaataca acttgaagaa gcactaaaga
    38521 gtggtaaatt tatatttcat aaagttggtg atgaagttca tgtgttagag gacataaata
    38581 cttttgtatc atttacagat gataaaaatg acgatttttc aagtaaccaa agtgttagag
    38641 tacttgacca aattgctaat gatatagcga ctttatttaa tacaaagtac ttgggtgaag
    38701 taccaaatga taaatctggt cgtatctcgt tttggaatga tgtagttaag catcatgaac
    38761 aactgcaaaa tatgagagca atagaagatt tcaaagctga tgatgtttct gtagaacctg
    38821 gaagcgacaa gaagactgtt gtagtaagtg atgctgtaaa agttattagt gctatgagta
    38881 agctttatat gactgtttca gttagttaac aataagaaag gagaataata atggcacaac
    38941 aaataaaagc aagagataca ataagtgcat ctaaggcaga gtgttttgta actataaaag
    39001 gtaaaagata taattttatg caagctatta acttagaagc taaaatggaa aagaataaga
    39061 gtgagatacc tatattaggt agtactacaa aaggaaataa atcaacagga agtaaatatt
    39121 caggaaatgc aacattttat tataatacct ctatatttag agaattgttg tatgagtata
    39181 aagaaactgg tgaggatatt tacttcgata tacaaattac caatgaagac ccaacaagtt
    39241 cagtgggtcg tcaaactata atactggaag attgcaatat ggactcaggc ataattgcta
    39301 aatttgatgc tgatggggag tatttagatg aagatatgga ttttactttt gagaattgga
    39361 aattagttga gaaatttaat atagcaaatg gtatggagta aaatacacat ttatgattta
    39421 tgtatgtgta ttttttattt ataagaatag gagatgatta aaattaagga taaatatgag
    39481 ataaaagatt caatttcttt tgattatagc aataaaagac ctttggaaga acgtgtcagc
    39541 gagatgtata aaaaggcagg aaaatatctt atagatattt cagataagtt agcaacagat
    39601 acaattgatg gttcgtcatt aaagtcaata atcataaaat ttgaaataaa tgaagctggt
    39661 gttgcaacaa tagaaaaaca aacaaaatat ttggtgatgg aggtagaata agaatatggg
    39721 agatttaaac gcttttttaa gtcaaaatgc aataaaagta gagaatagaa agtatgtggc
    39781 aagtgaaagg tttataggag aagatggaaa agcaatcgaa tgggaactta aagcaataga
    39841 ttcagatagg gacagacaat taagaaaaga ttcaactata agagtaccta tattaaataa
    39901 aaaagggaaa gctacaggac aatacactag tgaaacagat tttaatactt acactttgaa
    39961 attatgtgtg gaaactatag tatttccgga tttacatgat gcagaattac aaaatagtta
    40021 tggtgtaatg ggtgcagagg agttattaac aacaatgttg actcctggcg aatatacaga
    40081 cctttcaagt gaggtaggag aggtaaatgg ttttgataga acttttgaag ataaagtaga
    40141 agaagcaaaa aactaattta tgaaggtgat tatgattcta atatagctca ttattgcctt
    40201 cataagttta aatggaaacc gcatgaatat atggatttac cagttgatga aaaagcattt
    40261 gttgctgctt ctatagatat caaagtagaa gaagaaaaag aagaagctaa aaaagctgac
    40321 aaagatgcaa agagaggtag aagaagataa tctctggtgt aaaaatttta ctaatatagt
    40381 ataatatatt taaaaattgt actgggggat taaataaatg ggattgttta gtaaaaagaa
    40441 taagaaacct tgttgtattt gcggaagcga aaaaggactt atgccatcta tagaaggtga
    40501 aaatttttgt acagcttgta attgcaagta catagatttc tctgaaaata ttttaaaagt
    40561 aactagtatt atgaaaatga tgtcaaactc agaaggaatg aaaaagttta tagaagttga
    40621 aaagaaaaat ttaaaattgt tagagaagtt caccgagaca aaaagtataa attcttcaat
    40681 ttcttttgat gaagagcaaa atcttttaaa aatatcatat aaaaatagaa atcaaatatt
    40741 agtagagaaa ataataaaat ttgatgatat attagaattt gaacttttgg aagatggaga
    40801 aactatagtt aaaggtggtt taggtcgtgc tataactgga ggagtcttat tcggaggtac
    40861 aggggctgta gttggaggaa ttacaggtaa aaaaacaagt agaaaagttg tagaaatatt
    40921 taaaataaaa ataactgtaa aggacataaa taatccaatt gaatatataa atttaattaa
    40981 tagtaaagta aaaacaaact cttctattta tcagaaagct ttttctgatg ctcaagaaat
    41041 attatcaata ctatcaataa ttacaaaata taatgtaatg gaagacaaaa aaaagtctat
    41101 atctagttct acagctgatg aaatattaaa atataagaat ttgttagata tggaagctat
    41161 tacacaagaa gaatttgatg ctaagaaaaa agaattgcta aatttataat atataagcac
    41221 ttacttaaaa ataagtaagt gcttatatta tgttaaaaaa gaaaggaggt taaaaatggc
    41281 aactatacaa acatctatcc gaattttcga cggaatgaca cctgctttta gacacatgaa
    41341 taatgctatg aatattgtat taagttcatt cgagcaatta caaagaacat ctagcaatgc
    41401 tatagatgct aatagtatta gaacagctag agaagaacta gcacgtgcag aagctggctt
    41461 tgatagacta gaacaacaaa taagagaatc agataatcaa cagcgaaggc ttaatgagga
    41521 tataaataag ggtgcaagtt ctacagatag attagttgga agtgcaaaga agctagcagc
    41581 aacctactta ggtataagaa cgttaggagg tctaggaaat ttaagcgacc agatgacaag
    41641 tactaacgcg agacttagta tgataaatga tggtcaactc tcagatggag gattaaataa
    41701 gatgattttc caatctgctg aaaggtctcg tgcatcttac ttagatactg caaaaatagt
    41761 ttcacgaata ggcatgaacg caggtaaggc gtttagcagt acaaaagaaa ttgtaggttt
    41821 tgcagagcaa ctaaataaaa agttcgtaat tgctggagca agtactgagg aaatgaattc
    41881 ggcattgtta cagctaaccc aagggttgag ttctggtgta ttaagaggtg aggaactgaa
    41941 tgctgtgttt gagtcagcac ctaacatcat ccaatcgatt gcagattatt tggacgtgga
    42001 cataggaaaa ataagaggaa tggcatcaga gggaatgtta acagcagata ttgtaaaaaa
    42061 ctcattactt gcagcagcag agcagactaa tgcagagttc gagaagatgc cttatacgct
    42121 aggtcaaatc tttactagtg taaaaaataa tgcagttatg gtatttggag ctatacagaa
    42181 gaaaattgag gacacagttt caagcagggg atttcgaact ttcataactg atgttaaaga
    42241 ctcattatat gtacttggag cagttgggtt taatgtattt agtggattta ttaatttact
    42301 gagtagtcca gcttttcaga atttttttaa tgtgatgatt gttggaacta gtttagttgt
    42361 acaagggcta ggttggataa taacacaagc acttagtgtt gctaatgtat tttcgcgaaa
    42421 ttggagtata atttcaccta taattttagg tgtagtttca gctattagta cctatataat
    42481 agctcttggt attatgcaag cagttactat agctggaact gtagcaaatt ggatgtcgtg
    42541 gacatctgaa gttattagac aaagaggaat tttaggaaca gctagagctt tagcgatagg
    42601 caaagctgaa caatggggat ttaatgctgc tatatatgca tgtcccattt tttggatagt
    42661 tttaggtata attgcagtaa tatctgctgt atttatatta gtagcagttt acaatcactt
    42721 tgcaggcaca agtatttctg caatcagtct tatagttgga gcttggtatt ggttatgtgc
    42781 agttgtttac aacgtaattg tagggatagt aaatgctata aatatctgtg tggttgaaat
    42841 agcaaatatc tttagaactg gattatatgc agtgcaatgt ttctttattg atatggctaa
    42901 tgcaggactc aaggcaggtg ttaatttaga caaagctttt gataaatttg ctaccaatct
    42961 agcaaatggt attataaaag ctgttaatat agctgtaaaa ggattgaatt ggttagtaca
    43021 acagattaat aaaattccag gaattgattt accacaaatg aaagaatttc aaaaagtaaa
    43081 tactgtaatt ggtacaaaaa caacatttaa acccattcaa aaaccgcctg agcctaaagc
    43141 atggaaacca gaattagtag agtacaaaaa tttaaagtca gaatttataa aaggatatga
    43201 cgtaggacat caattacaaa acaaatttaa agatactttt gacattagca agatagccga
    43261 aaaagcaaaa aaagatttag gtctagatga cctttgggat aaaaaatacg gacttggtga
    43321 tggattgggt tcagctggat taaattcacc tttgagtgac gcagcaaaag gagcaaagga
    43381 cacagcaggc aatactgcaa aaatggcaaa gactatggat aaaagtcaag aggacttaaa
    43441 atatcttaga gacattgcag agcaagaaac aataaaccga ttcacagggg taaatataaa
    43501 aattgacatg aacaacacta ataacataag taaagatgca gatgtggatg gtatagttaa
    43561 tgtactaaca gaaaaactga atgatgctat ggttgtatct gctgagggaa tagtttagag
    43621 aggaggtgta atcgtggctt atgattttta tttagatgga gtacaattac caatacctcc
    43681 accaaagtta gagattaaag ttacaaataa aaataagaca gttgatttga taaatactgg
    43741 agaagtaaac atattaaaaa aagaagggct atctgaaata agttttgaag cagagtttac
    43801 acataataaa ttaccttttt atcgtggaac ttttagggat gttcaattct ttttaagtaa
    43861 gctagaatta ctaaaaactg attgtaagcc atttcaattt attgtatcga gggaaatggg
    43921 tggaaaagta ctatttaaca ctaatatgaa agtgtcatta gaagaatata acatagtaga
    43981 agatgcagac aatggttcag atgttaaagt tgcaataaag ttaaagcaat atagagatta
    44041 ctcaactaaa aaattagttc ctgcaactcc tgaaaagaca aactatggta ggactcccac
    44101 tccagtcatg aaaccaaaag aatttagacc agattcatcc aataagccaa atggtaaaac
    44161 atatacagta aaagcagggg atagcctttg gtcaatctgc cagaagcaac ttggtaatgg
    44221 ttcattatat aagaaagtat atgagttaaa taaaacaatg atggataaag ctaacaaggg
    44281 taaaaaagta cctaaataca caatttacaa agggcaggtg ttaaaacttg gctgatgaat
    44341 tagttctggc aaatgatagg gatgtaaggc tagttattgc acattgggaa gatttctacg
    44401 aaccagttgt ccttgatggt atcacatggg agatagaaag aagaggaaca ccttctaagt
    44461 tagaatttac aatagttatg gatgatatat tagagttttg cgaaggaaat tctgtaaggc
    44521 tgtattataa aggaataggt atcttctatg gatatatatt tcagaagaaa agagataaag
    44581 aaaatcacat taaaattgtt gcttacgacc agctaagata ttttaagaat aaagatactt
    44641 atgtatatag taataaaact gcaagtgaac ttgtaaaaat gttggctaaa gattttaatt
    44701 taaaatacaa tgtcatagaa gatactaagt ataaaatatc taggatagaa gaaaataaaa
    44761 cactctttga catgatacta acagcactag atgatactct aagagagaaa aaggaaatgt
    44821 atgttttata tgatgagttt ggaagaataa cattaaagaa tgttgcatca atgaaacttg
    44881 atacggttat gaacaatgat gtaattgagg attttgacta taattcatca atagatagtg
    44941 atacttacac aaagattaaa cttgtcagag acaacgagga gtcaggaaaa agagatgtgt
    45001 atattgcaca agattctaca catatgagaa gttggggaat actacaacta tttgatacag
    45061 tagataaaaa catgagtgaa gcagagataa agcaaaaatg tgatatactt ctaaaactat
    45121 ataataagaa aactaagtca ttaagtttaa aaaatgtgtt aggagatatt agagtaagag
    45181 caggttgttt agtacctgtt tttttagatt taggagatat tgatttacaa aattatatgt
    45241 tagttgagaa agtaaagcac acatttgaaa ataattcgca ctttatggat ttgactcttg
    45301 ttgatggaga tgaatttgct tcttattctt caagctcata tagtagtgga aatactaata
    45361 ataaagatga aaagaaaaat ggtcctgcac aaagtactac aagtaaagaa gacaatgata
    45421 tgataaataa attaaataaa gtatttaaaa ataagttatc aaatacagga agtatatttg
    45481 ttaaatattc taatgcttac aaagtcaatg cagctttaat ggctgctatt tctatacatg
    45541 aaactggtaa tggaagttct tcactttgta aaaataaaaa taatttcttt ggaatgaaag
    45601 gaatgtcttt tggctctgtg gatgaaggaa taaaaagagg tataagtaat ttatcaagaa
    45661 actatatcca tatgggaaga aaaacattag aaagtattag agacaaatat gctccacttt
    45721 atgatagtcc tcttaataaa cattgggtac caggagtaaa taagttttat aaacaaataa
    45781 cgggaaatgc atatagttct aatagtgcag gtacaggtgt tagaagcaac gaggaagcag
    45841 aaaagaattt aaaagatata acttatcaag ttcaaaatag caacaatgct aatacatcaa
    45901 caaacaataa tagtaaagta aataaagtta ttcaagaagc aaaaaatcaa cttggcaagc
    45961 cttacaaatg gggtggtaat ggtccaaaga gttttgactg tagtggtctt atggtgtggg
    46021 cattcaaaag aggtgcaggt ataaatctca aaagagtttc agcagaccaa tcaaatgata
    46081 gtagaggaaa actattatgc aacataaatg atgtaaaagc tggcgattta gtattctttg
    46141 catacaacca aggaaaagga aatgtacatc acgttggact atgtatagga aatgacaagt
    46201 tcatacattc accaaatact ggtgatgtag ttaaaataag cagtttaagt ggtagacaaa
    46261 aacaaaaaca tgattttgca agagctagaa gattctttta agtgaggtga taatatgagc
    46321 caagatttat tacaaataat aaagaaagct gcaatggatg cagtagaaac aagcaaccca
    46381 atgcagattg catttggaac tatagaaagt gttaatcctt tagtagttaa gatagagcaa
    46441 aaagcctctt ttgaagaatc ttttctaata caaacagata catttaaaag atatacagat
    46501 aaaaagatag gagataaatt agtcttaatt aggatgcaag gaggacagca atatttgatt
    46561 ttagatagga tgtgatgaaa tgttaccaac agataacatt gactatgata tagaagatgt
    46621 atcgataatt aattttgatg taaggcaaga accaagtaag acctttaaat taaatataga
    46681 aaaatctaag atagatggta tttgtgatga tgttgaagca ttaaaacaaa ccatcttttt
    46741 aattttaaac acagagagat accaacatct aatatatagt tggaattatg gagtcgagtt
    46801 gaacgacctt attggagagc ctatatcctt tgtaatcccc gaacttgaaa gacgaatcaa
    46861 agaagcacta attcaagatg atagggttga aaatgtagat aattttgagt ttcaaaatgt
    46921 aaagggtaaa gtacattgta agttcacagt ttacagtaaa tatggaaata taaaagcaga
    46981 gaaggtggtg agtgtataat tgtttgagtt aatgacattt gaaaatataa ttaaaagaat
    47041 gttagatagt gtaccagata cttttgataa aagggaaggt tctataatat ataatgctct
    47101 tgctcctgtt gctatagaac ttacagaaac atacattgcc atggatgaat tactagacca
    47161 aacttttgta gatactgcta gttattacta tttagagaag agatgtaaag aaagaggtat
    47221 tacaccttta cctgcaacca atacaattgc aaaaggagtt tttaatatag atattcctat
    47281 tgattcaaga ttcaacttag gagaatacaa ttatgtggca attgagagaa tatctgaaaa
    47341 aacatataaa atgaaatgtg aaactactgg acctgtattt gaacttggtc agttgattcc
    47401 aattgaatat gtagacaaat tagaaactgc tgagttaact gaaatactaa ttaatggaga
    47461 agatgaagaa agtgaagata gtttaagaca aagatattat gatagcctaa actcacagag
    47521 ttttggtgga aatatgcaaa attataaaga tgaagttaac aaaatacaag atgttggagg
    47581 agttaaggtt tatcctgtgt gggacggtgg aggtactgtt aagttagtaa taattaattc
    47641 taacttcaaa gttccatcta gtgatttagt taatttagtt caagaagaaa ttgatcctct
    47701 acaaaaccaa ggagaaggtc ttggattagc accaattgga caccgagtca cagttgaagg
    47761 agttacaagt acaactataa atatatcagc agagataaca tacaaaaatg gctacacttg
    47821 ggagaatata aaatcaattg cagaagaagc aatagacgac tatttaaatg aacttaatat
    47881 gagttgggaa gatgaagaaa acttaatagt tcgtatatct caaattgaaa ctagattact
    47941 tagtattgat ggagtattag acattgcaaa tacaatgata aatagcattg catctaatct
    48001 taatgttgat aaagattcta tagtattaag aggtgaagta gttggataaa gagattaatc
    48061 taataaatta cttaccgcaa atcctacgag ataaagaaga atatataaaa gtatttaatg
    48121 tagaaaacaa agaaataaaa acactacatg aaaaattaaa tgacctatca aatgaccagt
    48181 ttttagagga tttaactcca agtggcataa aaagatggga aaagataatg tctataactc
    48241 ctaaaagtaa tgagagttta gaagatagaa ggtttaggat ttttagtaaa tatataagta
    48301 aattacctta ctcagagaga tttttaagga actggctaga taatgtagtt ggagaaggca
    48361 attatgagtt aactat
//
LOCUS       DAEHWO010000025        47723 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEHWO010000025 DAEHWO010000000
VERSION     DAEHWO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.025"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            224..1057
                     /locus_tag="KNP54_001676"
     CDS             224..1057
                     /locus_tag="KNP54_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBF0892581.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDQMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            1150..2082
                     /locus_tag="KNP54_001677"
     CDS             1150..2082
                     /locus_tag="KNP54_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBF0892582.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            2134..2616
                     /locus_tag="KNP54_001678"
     CDS             2134..2616
                     /locus_tag="KNP54_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0892583.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            2628..3497
                     /locus_tag="KNP54_001679"
     CDS             2628..3497
                     /locus_tag="KNP54_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBF0892584.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            3540..4295
                     /locus_tag="KNP54_001680"
     CDS             3540..4295
                     /locus_tag="KNP54_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBF0892585.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLASLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KEDNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            4337..5158
                     /locus_tag="KNP54_001681"
     CDS             4337..5158
                     /locus_tag="KNP54_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBF0892586.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            5163..5924
                     /locus_tag="KNP54_001682"
     CDS             5163..5924
                     /locus_tag="KNP54_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBF0892587.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    6085..6342
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6455..6694
                     /locus_tag="KNP54_001683"
     CDS             6455..6694
                     /locus_tag="KNP54_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBF0892588.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            6998..7993
                     /gene="ilvC"
                     /locus_tag="KNP54_001684"
     CDS             6998..7993
                     /gene="ilvC"
                     /locus_tag="KNP54_001684"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBF0892589.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDVAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            8046..9734
                     /gene="ilvB"
                     /locus_tag="KNP54_001685"
     CDS             8046..9734
                     /gene="ilvB"
                     /locus_tag="KNP54_001685"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBF0892590.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            9945..10622
                     /locus_tag="KNP54_001686"
     CDS             9945..10622
                     /locus_tag="KNP54_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBF0892591.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            10791..12827
                     /locus_tag="KNP54_001687"
     CDS             10791..12827
                     /locus_tag="KNP54_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBF0892592.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPAGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(13018..13584)
                     /locus_tag="KNP54_001688"
     CDS             complement(13018..13584)
                     /locus_tag="KNP54_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0892593.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRKRVNKND"
     gene            13872..14807
                     /locus_tag="KNP54_001689"
     CDS             13872..14807
                     /locus_tag="KNP54_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0892594.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            15272..16486
                     /locus_tag="KNP54_001690"
     CDS             15272..16486
                     /locus_tag="KNP54_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892595.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(16906..17427)
                     /locus_tag="KNP54_001691"
     CDS             complement(16906..17427)
                     /locus_tag="KNP54_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0892596.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHKQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDNFIYVEHFCIFPEIRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHKKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            17783..18580
                     /locus_tag="KNP54_001692"
     CDS             17783..18580
                     /locus_tag="KNP54_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBF0892597.1"
                     /translation="MEKREKRIIISSLLSVSILMGLASIYSILNKEDISLTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            18690..19280
                     /locus_tag="KNP54_001693"
     CDS             18690..19280
                     /locus_tag="KNP54_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBF0892598.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            19346..21043
                     /locus_tag="KNP54_001694"
     CDS             19346..21043
                     /locus_tag="KNP54_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBF0892599.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            21257..22096
                     /locus_tag="KNP54_001695"
     CDS             21257..22096
                     /locus_tag="KNP54_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBF0892600.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            22613..24469
                     /locus_tag="KNP54_001696"
     CDS             22613..24469
                     /locus_tag="KNP54_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBF0892601.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGTYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    24552..24792
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    24858..25093
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25178..26395
                     /locus_tag="KNP54_001697"
     CDS             25178..26395
                     /locus_tag="KNP54_001697"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBF0892602.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            26512..26994
                     /gene="cdeM"
                     /locus_tag="KNP54_001698"
     CDS             26512..26994
                     /gene="cdeM"
                     /locus_tag="KNP54_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBF0892603.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            27258..28523
                     /gene="hisD"
                     /locus_tag="KNP54_001699"
     CDS             27258..28523
                     /gene="hisD"
                     /locus_tag="KNP54_001699"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBF0892604.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(28726..29478)
                     /locus_tag="KNP54_001700"
     CDS             complement(28726..29478)
                     /locus_tag="KNP54_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0892605.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIYIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(29596..29865)
                     /locus_tag="KNP54_001701"
     CDS             complement(29596..29865)
                     /locus_tag="KNP54_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892606.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            30340..31434
                     /locus_tag="KNP54_001702"
     CDS             30340..31434
                     /locus_tag="KNP54_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBF0892607.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            31436..32386
                     /locus_tag="KNP54_001703"
     CDS             31436..32386
                     /locus_tag="KNP54_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBF0892608.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            32379..33563
                     /locus_tag="KNP54_001704"
     CDS             32379..33563
                     /locus_tag="KNP54_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892609.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYKKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDAFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            33576..35072
                     /locus_tag="KNP54_001705"
     CDS             33576..35072
                     /locus_tag="KNP54_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBF0892610.1"
                     /translation="MSKILEIQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            35095..36045
                     /locus_tag="KNP54_001706"
     CDS             35095..36045
                     /locus_tag="KNP54_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892611.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            36066..37028
                     /locus_tag="KNP54_001707"
     CDS             36066..37028
                     /locus_tag="KNP54_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBF0892612.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            37400..38032
                     /locus_tag="KNP54_001708"
     CDS             37400..38032
                     /locus_tag="KNP54_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBF0892613.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            38443..38535
                     /gene="kdpF"
                     /locus_tag="KNP54_001709"
     CDS             38443..38535
                     /gene="kdpF"
                     /locus_tag="KNP54_001709"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBF0892614.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            38576..40258
                     /gene="kdpA"
                     /locus_tag="KNP54_001710"
     CDS             38576..40258
                     /gene="kdpA"
                     /locus_tag="KNP54_001710"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBF0892615.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGVVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            40283..42340
                     /gene="kdpB"
                     /locus_tag="KNP54_001711"
     CDS             40283..42340
                     /gene="kdpB"
                     /locus_tag="KNP54_001711"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBF0892616.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            42359..42985
                     /locus_tag="KNP54_001712"
     CDS             42359..42985
                     /locus_tag="KNP54_001712"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBF0892617.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            43222..44130
                     /gene="cysK"
                     /locus_tag="KNP54_001713"
     CDS             43222..44130
                     /gene="cysK"
                     /locus_tag="KNP54_001713"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBF0892618.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            44157..44747
                     /gene="cysE"
                     /locus_tag="KNP54_001714"
     CDS             44157..44747
                     /gene="cysE"
                     /locus_tag="KNP54_001714"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBF0892619.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            44907..45095
                     /locus_tag="KNP54_001715"
     CDS             44907..45095
                     /locus_tag="KNP54_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBF0892620.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(45149..46018)
                     /locus_tag="KNP54_001716"
     CDS             complement(45149..46018)
                     /locus_tag="KNP54_001716"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBF0892621.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(46215..47459)
                     /locus_tag="KNP54_001717"
     CDS             complement(46215..47459)
                     /locus_tag="KNP54_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892622.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDGLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
BASE COUNT        18905 a         4903 c         8389 g        15526 t
ORIGIN      
        1 actagaatta attgtaaaaa acactatata atactcaatt ttcaacattc tatacaatta
       61 tacagaaatt atacagcata ataatcaccg aaataacaaa ttttaaaaat taagcaaaac
      121 tttttgtcga agttcaacgt ctatatatat gtagtgtaaa tttttgggat aaaatactac
      181 aaaaatataa atgtaaaaat atagtaatat tggaggtcga acgatgagaa ataaaaagaa
      241 aaaaataaat agaaagaagt tgtatttgct tttaagtgct attgtagtgt gtctggcttt
      301 tatagtagtt ggtgttcgcg tcagctcttt aaatatgaag gaaaatgaaa ttagtagaaa
      361 tgcaaaactg tcaagttcta ctattacaga tatagtatct aatacatcaa tagaagttag
      421 taaagggcca agtaaaagtt ctggaaaaat agcatacata actatagatg atggtccatc
      481 taaatttact gaccagatga taaaaacttt aaataaatac aatgttaaag caactttttt
      541 tatgatagat gggaatatga aggaatatcc acagcaagtt aaaaatataa ttaaaaatgg
      601 gaacacagca ggttttcata gtgtatcaca tgatattcac aagctttatg ttactagtac
      661 atcagcaaaa gaggaatttg atacaaatga tcaaactttt tataagataa ctggtaaaca
      721 ttcaaaagta ataagaatac cttatggaag caaaccatat acaccacaag cctcttatca
      781 ggctttagtt gatgctggat ataaaatttg ggactgggac ttagatacag aagactggag
      841 atctaattct tctcaaattg tacaaaatgt aaaaaatcat attaagaata gaaaaggtga
      901 agataaagac caacttgtag ttttaatgca tgagaaaaaa cagagtgcag aagctttaga
      961 ttcagtttta aaattcttat cagatgaagg ttatgaattt gcgccagtag atcaaaacca
     1021 aataccaaaa aattattggt tacgtaattt agagtagtta aaatataaga atattgattg
     1081 atatttttag aaattgagaa taaaaatgag tgaggtgtag gtatattgaa taaaaaactt
     1141 tatataggaa tggtcggaat attgtctttg atgatggttg gttgtaataa aagtttagca
     1201 aaagtaaatg atgtggaaat cacaaaagaa cagtacaaaa aaacaaaagc agttttatct
     1261 gctactaata attatataaa tgggcagtct ttagatgaat tagaaaaaac tttggataaa
     1321 aaaggtagaa ataaattaga aaatgttata atatcgttta tggtggataa tgaactttta
     1381 tatcaagagg ctaaggataa aggactaact ccaagtaaaa gtgaagtaga ctcaaaatat
     1441 caagaactag aagataagat gaatttgaat acaagctata aggaaaaaat ggacaaagca
     1501 ggtgttgata aagattattt aaaacaagaa atatctagag atttagcaat agataaaaat
     1561 aaaaaggcct ttgaagatag aataaacata agtgataatg atatggaagc ctactataca
     1621 agtcataaaa aagattttaa tgtagaagaa gtaagtgctt ctcagatact tatatcgact
     1681 ttagataaaa ataaaaaaga agtaagcaaa gataaaaaag aagctttgaa gaagaaggca
     1741 gataatatat tgactaaaat caaaaatgga gaaagttttg aaagtttggc taaaaaatat
     1801 tcggatgata aagcaactgg aaaaaatgga ggacagctag gatattttac aaaggatgat
     1861 aaaaatgctg agtttacaaa ggaagtgttc aaattaaaga aaaatgaagt ttcaaatgtg
     1921 tttgaaacta gttatggata tcatatagtc aaagttactg ataaaagaga aagacaaaaa
     1981 agttttaatg agtgtcagag tttaataaga gaatctattt taaatgaaaa gtatattgag
     2041 catataaaaa aactgaatga agatgctaaa atagacagat agaatttcta acagctcaat
     2101 cctagcctgt aatcggaggg agattttaca ggaatgttta agagtttaaa gagaacgaaa
     2161 gttgagaaat acattatcga taataaagac tctttttata gaatagcata tagttatacg
     2221 aagaatgaag aagatgcctt agatgtggtt caagaagcca tgtataaggc actatactca
     2281 gtggaaaata ttaaagaagt aaattatata aagacatggt tttataaaat tttagttaga
     2341 acgagtatag attttattag aaaaaaccgt aaatataata atatgacaga tattgacctt
     2401 atagatgaga ctggagagta tgataaatat actgatttgg atttaagaag agctttggaa
     2461 gaattaccta ttgaatacaa atctattata atattaagat tttttgaaga tttaaagatt
     2521 gaagaagtag caataatatt ggatgaaaat gtgaatactg ttaaaactag gttatatact
     2581 gctttaaaaa aactaaaatt aaaaattgaa gagtagggat aaaaagaatg acaagcaaag
     2641 aaaggttaaa taagttaaaa gatgagtatc ataaaattcc aatacccaag aaattagata
     2701 ctataataaa tcatgaaaaa atagaaaaca tatatcgaga gaaaaataaa aaagtaaata
     2761 gattaagatt taaagttgca atagcctttg catgtatatt tacagtatta gtaaatataa
     2821 gtcctgtatt tgcagacaat ttttctaaga tacctgtaat tggagcaata gtagaagtaa
     2881 taactataaa aaattatagt ttaaaaagtg aaaattatga agctgagatt gatattccta
     2941 aaatacgagg tttaaaagat aaaaacttag aacaaagatt aaacagtagt tttatggaag
     3001 atggaaaaag gctttatcat caattccaag agagaatgga gaagatacaa tcatcaaaga
     3061 ataaaggata taaatcttta agtttgagtt atagtgtaaa aaataattct aaaaaatttc
     3121 tatcaataga gatgacaaaa aatgagatag aggcttcatc atatgtgagt aaggtacatt
     3181 atactattga taaaaaaaga caaatagttt tgactttgcc aatgcttttt aaagatgata
     3241 agtatataaa agttataagt gataatataa aagaacaaat gagagaacaa atgaaaaagg
     3301 atagtacaaa atcctatttt atagatcaaa aaaaagactt gcctgttgaa gattttaaaa
     3361 caattaataa gtatcaggat ttttatttta ataaaaatga agaccttgta atttgttttg
     3421 atgaatatga agtagcacct ggttatatgg gcgcagttga gtttgtaata ccatataaag
     3481 taataaaaga tttgtaaatt gaatagtagt ttatatataa atcttttaag gaggacaata
     3541 tgactacata taaaaaactt aaaaaatcta tatttaaaat tgctatattt tcaatatgct
     3601 tattagcttc attagtagat acaaacccta tatttgcagg tagttccttt aatgaaactt
     3661 caaatagtga tacgataaag gtgttaaatg ctaagagtat caactttaaa caagacaatt
     3721 atgaagtgaa tgtgagtatt cctaaaataa aaggtttaaa agataaaact ttagagaata
     3781 aattaaacaa tgagtttttg caagatggga aaaaaattta cagtgaattt caaaataaaa
     3841 tgaaaaagga agataataag ggtcatagat acctaaatgt aatccataat gtcaaaaata
     3901 attctaagga ctttttatca atagaaatga caaaagaaga gatagaagct tcctcatcta
     3961 taactaagaa gcattacact gttgataaaa atagaggaat actattaaat ttaccaatat
     4021 tttttaaaga tagtagatat attagagcta taagtgataa tataaaagag cagatgagaa
     4081 atcaaattaa gaaagatgat acaaaatctt attttataga ccaagataaa gactcgccag
     4141 tgaaagattt tgaatctata aataagtatc aagattttta ttttaataaa aatggaaatc
     4201 ttgtgattag ttttgatgaa tatgaagtag ctcctggtta tatgggagca gtagaatttg
     4261 tgataccaaa taaagtaata aaaagactaa gatagatata tagaagattt ttagatagac
     4321 tggtaaggag aattatatga atatatatga acaagcaata agattaatag aaaataatga
     4381 ggatttcgca tttgctacaa taacgtctca ttcaggttca acaccacgtg aaactggagc
     4441 aatgatgatt gtgaaaaatg attctactat atttggctca gtaggaggag gtagtgtaga
     4501 agcagaatgt ataaaacatg caattaatgt tataaaaaac agagaatcaa tgttgtataa
     4561 atttactcta aacaaatctg atgttgcaaa actaggaatg atatgtggag gtactggaga
     4621 aatacaaata gattttatag atagtaaatt aaaaagtaat atagaaaaat ttaataagag
     4681 actaaaggaa aatacaagta aagcatatat atttggtgca ggtcatattt caagagatgt
     4741 tgctgtgata ctatctcttt tagaatttag aacagtagta atagatgata gagaagaatt
     4801 tgctaatcat gaaaggtttc cagaatcaga agtagtagtt ttagattctt ttgaaaacat
     4861 accagatttt ccaactgacg aaaatagtta tataattatt ttaacaagag gtcatctata
     4921 tgattcaagt gctttagaat gggctcttaa aagagaggct ggttatatag gtatgattgg
     4981 aagtagaaca aaaattggat tgacttacga aaaactcatg aaaaaaggtt ttaagaagga
     5041 agaattatca aaagtacatg caccaatagg cataaaattg aatgctcaaa caccagctga
     5101 aatagctgta tgtatagctg ctgaacttat aaattgtaga gctaataagg aaaaataaac
     5161 taatgaacac agggagtaaa gatattgata ctttaaaggt taattttaga gggattgaaa
     5221 taaaagcagt tttagtatat aaaaatagaa aaaatatttc tataaaaata gatccatttg
     5281 gcaaaataac tgtaatgagt cctcctaaaa tatccaaaaa aataataaaa gatataatta
     5341 ttgaaaaagg agactggata cttaaaaagt cagaaaaatg taaaggaaga gaggaagtat
     5401 ataaacaaag aatgtttata actggcgaaa aatttcttta tttaggtgaa gagtaccatt
     5461 tagttataaa agaactgttg agagattctg tcaaaaaaag taactgtaga ataactatta
     5521 acgaatatca aatagttgtt cagacaaatg atacaagtac agattttatt aaaaaatctt
     5581 taaaatcttg gtataagatg gaaagtgaaa gaatagtatt agagagaata gattttctta
     5641 aattaaattg tgaaataatg aagcaattag ttccagcgag tgttaaggta aaagaacaaa
     5701 ataagagatg gggaagttgt acagctcaaa aaaatattta tataaactca aaaatatcta
     5761 tggcaagatt agatgtaatt gattatgtaa taatacatga gtttagccat ttagtacata
     5821 tgaatcactc taaaaaattc tatgatttag taaaatccat tatgcccgat tataaagata
     5881 aagaaaattg gctaaaaata aatggatata aaataataat ctgaaaacga ttattccaaa
     5941 atataggcgt aaagtataaa agaagtatta ttgtgaaaaa aataaataat ctgaaaattt
     6001 taaaaaaagt cattgacatt gtaaatgata gggaatataa tctatattaa caacaaaaca
     6061 gaattaaaat ataaaattaa aaaattaaaa gcaatgacag agacaacaat actaatagtg
     6121 ttatccacag agaaccaatg ttgctgagaa ttggtgttaa cagtagtata atgatcactc
     6181 tggagctttt gtactgaata tttttagtaa gtacaaacgt atgtcagcgt tacatgacta
     6241 aggttaaggt aattaattac ccgacctgaa aaaagagggg tagatgtatt ttttatatct
     6301 acaaataagg tggtaccgcg gaatataact ttcgtcctta taagtaatat ttatattgct
     6361 tataaagatg aaagtttttt tattttaagc gatataaata aatttaatcc atataaaatt
     6421 aataaaaaaa taataaaaat aaggagggat ttttatggaa aatactgtat atgctaaatt
     6481 aaaccaagga atagattctt ttttaagagt ggctatgact ctaagaagaa gagaggttga
     6541 tatacaatca ataagtatga ctgtagataa tatgaataat tcaggtataa aattaatagt
     6601 aaatgaagaa aagacatcct tagattctgt cttaaaccat atgaaaaaac tacatgatat
     6661 aagagagata actgttgaaa gaatgagaca ttaattaaat atattttata aagctaaaga
     6721 taaatatgct tattttaaaa taaaaaacta aagataaata ttaaataaga aaaatcttag
     6781 attaaaatat aagtgtcatt gaatttatta gtttatcaca gttaataaat ttattagttt
     6841 gttgtagcta ataaaaactg aaaattctaa aattataatt gtaagattat ataaatttag
     6901 aatttaaatc tgttgaataa tattaaaaca atgataatga gtatgaattt ctaataaaaa
     6961 taaatatcat aaaaataaga aaaagtattg ggaggaaatg aaaatggcaa gaatgtatta
     7021 tgaaaaagat gtggatttag aagttttaaa aaataaaaag gttgcagttt taggttatgg
     7081 aagtcaagga catgcacatg cacaaaatct tagagataac ggtgtacatg tagtgatagg
     7141 tctttatgac ggaagtaaat cagcacaaaa agcaaaagaa gatggatttg aagttaagag
     7201 tgtagcagaa gctacaaaag aaagtgattt gacaatgatg ttaatgcctg atgaaaaaca
     7261 aaagaaagtt tatgaagaga gtgtaaagga taacttaaaa gaaggccaga cattagcttt
     7321 tgctcatgga ttcaatatac attataatca agtacaacca ccagaatttg ttgatgttgt
     7381 aatggtagct cctaaaggac ctggtcactt agttagaaat gtatttacaa agggaagtgg
     7441 agttcctgca ctatttgcag tatatcaaga ctacactaaa aaagctacag agacagtttt
     7501 agcatatgca aaagggatag gagcaacaag agcaggtgtt ttagaaacta cttttaaaga
     7561 agaaacagaa acagatttat ttggagaaca atcagtactt tgtggtggaa taagtgaact
     7621 tataaaattg ggatataaaa cgcttgtaga tgcaggttat caaaaagaag tagcatattt
     7681 tgaatgttta catgaaatga aactaatagt cgaccttata tatgaaggtg gatttgaaag
     7741 aatgagatat agtataagtg acacagcaga atatggagat tatgtatctg gtaaaagggt
     7801 aataactgat gttgcaaaac aaggtatgca aaatgtttta gaggatatac aaaatggaaa
     7861 atttgcaaaa gcgtggatta aagaaaatga agaaggacgt gaaaacttcc taaaaactag
     7921 agaagaagaa tataatacag aaattgccga agttggtaga aatctaagaa gtatgatgtc
     7981 attcttaaaa taaatatata ttaaatggat tagtttgagg gaaagagtgg tgtatagtag
     8041 tgcgtatgaa tggagcaaag gtaattttag aatgtttaaa gaaagaggga attgacacaa
     8101 tatttggata tcctggtgga gccgtgatac ctctttatga tgctctatac gattattcag
     8161 atgattttaa acatataagg acatcccatg aacaaggttt agttcatgct gcagatgggt
     8221 acgcaagaag tactaataca gtaggagttt gttttacaac atctggtcca ggagcaacaa
     8281 atgccataac tggaatagca acagctttta tggattcttc acctatggtt gtaatttcag
     8341 ggcaggtgcc aactagttta ttaggaaaag attcttttca agaaattgac ataactggag
     8401 caacattatc tatgacaaaa cataattatt tagttagaaa cactaaagaa ttagttccta
     8461 caataaaaga agcttttaga gttgcaaatt caggtagaaa aggacctgta cttgtagatg
     8521 ttccaaaaga tttattttta gcagaaatgg attttagtgg tgaggactat gatttatgtc
     8581 aaatagatga ttatatggat tataagagtg attttgatct agatgatgaa actaatatta
     8641 agcttttaaa tgaagcaata gatatcataa aagaatctaa aaagcctata atatatgcag
     8701 gtggaggtgt taaatcttca gacagtgagg aaattcttga aaaatttgca actaagatag
     8761 atacacccgt actaaataca cttatggggc ttggaaatat agatagaaag aatgaattat
     8821 ctcttggaat ggttggaatg catggaagta gagaaagtaa tttagcactt tctaattcag
     8881 atttagtaat agcgataggt gcgagattta gtgatagagt gataagtaaa agttctgaat
     8941 ttgctaaaaa tgcaaaaata atacacatag acatagaccc atctgaaata agtaaaaata
     9001 tagaatctaa tgtatctttg gttggagatg taaagctagt ccttagttta ttaattgaaa
     9061 gggttgaaag taagaataat agcaattgga aagaagagat aaagagattt agaaagagtg
     9121 agggtgtaca aacatatgaa tttcatccac aaaatatact taaaaaaata aatgaaaaat
     9181 atgaaacatt aaagaaaccc actgtggtag taactgatgt cggtcaacat caaatgtggg
     9241 ctgctaagta ctggaatttt aaaggtaata aaagttttat aacatcagca gggttaggaa
     9301 ctatgggatt tggtttaggt gcagctattg gaactaaagt tggtaatgta gataaaaatg
     9361 tggttttagt cactggtgat ggaagtttta gaatgaactg taatgaacta gctacagttg
     9421 caaattataa tgtacctatg cttattttac tactcaataa tagaacatta ggaatggtaa
     9481 ggcaatggca aaagttattt tccaatcaaa gatactctca aactgacatt aatgaaaatg
     9541 tggattatgt taaactcgta aatgcatata acattgatgg atataaggta tccagtatgg
     9601 aagaattagg aaaggcgcta gatatgatag attttaataa acctgtattt ttgcaatgtg
     9661 atatagataa ggattatgat gtttatccta ttgtagcacc taatgatgca ttggaaaatt
     9721 tgatatgtaa ctaaaactta tactgaatat tgataaaatt ttttattaaa tttttattag
     9781 tattcagttt ttgttgttta gagatagatt ggcatttttt atttttgcaa ataaatcaat
     9841 gactatataa ttaagaactt attaaatttt aattatacaa tttagaatag tattacaact
     9901 taagtaaata ataattttga ataataattt acggaggtat tcatatgttt aaacacgata
     9961 aagcattatt aaaagaagta aaagtagaaa gaccaaatcc tcaatatgct gttttaatgc
    10021 aagaacagtt gggtggtgca aatggagagt taaaagcagc tatgcaatac ttgtcccaaa
    10081 gttttagaat aaaagaccct caaataaaag atttatttct tgatatagca gcagaagagc
    10141 ttagccatat ggaaatggta gcacaaacta taaatttatt aaatggacat gatgttgatt
    10201 ataatgcagt taatacaggc gaaatagaaa cacatgtatt aactggtcta tcaccagtct
    10261 taataaactc atcaggagct ccttggactg ctaattacgt tacagttaca ggggatttag
    10321 tagctgactt actttcaaat atagcttctg aacaaagagc taaggtagtt tatgagtact
    10381 tgtatagaca aatagatgat aaatatgtaa aagaaacaat agatttctta cttaatagag
    10441 aagaagcaca taatgctcta tttagagatg ctttaaataa agttaaagat acaggttcaa
    10501 atagagattt tggagttaca gaagattcta aattatattt cgatttgtct actccagggc
    10561 caaatcacga tactaagata gatattaatc ctccttcttt tgaaaaacct ttaaaaaaat
    10621 aatttgatat tttttatttt gttttagtag ttataaaaat tatttactag aagaattaat
    10681 tatatgaaaa attaaatatg tatagttaaa aatgggtata cacttattat aagtgtatat
    10741 ctatttgttt attgcaaaac atataataaa ataacaaatg aggtggtatt ttggacagta
    10801 atagaaaacc taataatcta ataaatgaaa aatctccata tcttttacag catgcttata
    10861 atcctataaa ctggtatagt tggaatgatg aggcttttaa aaaagcaaaa gaagaggata
    10921 aaccaatatt tttaagtgta ggatattcaa catgtcattg gtgccatgtt atggaaaaag
    10981 aatcttttga agatgaagaa gttgctgaaa taatgaatag aaactttgtg gcaataaaag
    11041 tagataaaga ggaaagacct gatgtagata gtgtgtatat gacagtttgc caagctatga
    11101 caggtagtgg tggatggcca atgaccataa taatgacacc agataaaaaa cctttttttg
    11161 cgggaacata tttcccaaaa tattcaaggt ataatagacc tggagttata gatttattag
    11221 agaatgtatc tgaaaagtgg aatacaagca gagatatatt aataaaatct ggagatgaaa
    11281 taatagaagc tcttaaggat gattttggtg taaaaaatac tgagggtgat ttatcaaaag
    11341 agatgttgag ttcatcagtt agagtattta aggctattta tgatgaaaag tatggtggtt
    11401 ttggtaatgc tcctaaattt ccaagtcctc agaatcttat gtttttaatg aaatattata
    11461 gtatagaaaa agacaaagat gtgttaaaaa tggtggaaaa aactttagat ggaatgtata
    11521 gaggaggctt gtttgatcat attggatttg ggttttcaag atactctact gataaaaagt
    11581 ggttggctcc tcattttgaa aaaatgctat atgataatgc tatgcttact atagcttttt
    11641 tagatgcgta taaaataaca aagaaagagt tgtataaaga aattgctata aaaactatag
    11701 attatgtagt tagagagatg aaggataaag aaggtgggtt ttattcagca caggatgctg
    11761 atagtgaagg tgaagaaggt aaattttata catttaatcc tcttgagata attgaagttt
    11821 tgggtgaaga agatggaatt ttctttaata attattttga tataactagt agtggaaatt
    11881 ttgaaggcaa aagtattcct aatcttataa aaaataaaga atatgagaga cataatgaaa
    11941 agatagctga ccttagtaaa aaggtatttg aatatagaaa agaaagaaca tctttgcata
    12001 aagatgacaa gatacttaca tcatggaatg cattgatgat agttgcttta acaaaggcat
    12061 atagtacttt aaaaaatgac atatatttag agtattcaaa taagtgtctt aactttataa
    12121 ataataatct tgtaaatgag tcaggtagat tattagctag atatagagat ggaagttccg
    12181 actatttagc atatttagat gattatgctt ttttaatctg ggcgtatata gagctttatg
    12241 agtcaacatt taatatgaaa tatttagaaa aggctttaaa tttgaatgaa agctgtatca
    12301 accttttttg ggattatgaa aaaagtggat tttatatata tggtaaagat agtgaaaatt
    12361 taatagcaag gccaaaagat ttgtatgatg gagctattcc atcaggaaat tctgttcaat
    12421 tatacaatct tataagactt gcgaaaatta ctggagataa tagacttgaa gaaatgtcat
    12481 ataaacaatt aaaactgtat gtggataatg taaagagttc tccagctggc tacagctttt
    12541 atatgctttc attgatgttt gaactttatt ctactaagga aattatatgt atttttaagg
    12601 aagattctga tttaattgcc tttaaagaat tgataagtga aaattttata ccaaatgcaa
    12661 cttttttagc aaagaaatac aatgaagaaa acactattat aggtttttta aataactata
    12721 gattgaagga tgataagatt agttattacg tgtgtcaaag taatagttgt agtcaaccaa
    12781 ttaatgattt acaaaaatta aaagatatga ttttaggagt agaataatca taatagtgaa
    12841 aaaggagatg ctttaaaata aaagtctaat catctccttt ttttgtacaa aaaacagaaa
    12901 aagagttcct gagaacacct aatctatgta atgattgttt tgttaaaaaa taaaaatgac
    12961 attatagtta tataaaatat tgtactataa aaaagtagta ttatagatgc gatagtatta
    13021 atcgttttta tttactctct ttcttctttt tgcaaattct tcaagtgctt cagatttaat
    13081 tttatctatt tcttcatatt ccataaaatt agcatcttct tcaaagccat cttgttcttc
    13141 accattaaaa cgatacattt tttttagtaa actccataag gtctctaatt catctttggt
    13201 aaattcgtga aatacatctg ccataaagtt tattccagtc ctactacatg ttaccataac
    13261 cttttttcct aagtctgtaa ctttaacatt aattgctctc ttatcatgag gacttggaat
    13321 tacatcaaca tatccatttt tttcaagatt agcaactagt ctatttatat tttgtttact
    13381 tgtacccatt tttcttgcaa tattatttaa tgttgtttct tcctctggta aatgaagaat
    13441 tgataaaata gtcatatact gtcttgaagt aagtatacca aaatatttat ctccttctat
    13501 ttgtattttg tttgtaaggg taaaaagagt tgcatatgtt tgattcatta aaaagagttc
    13561 ttttagttca tttgaataat ccatgaaata tatctccttt atttttagat gttgttttgt
    13621 cgaaaacaga atatcatgaa ttaattctaa tgtcaatatg gtgtcaaaat atattaaagt
    13681 attacttttt tatgtaacta ttaattaatt aaattattgt ataattttat gtaaaaactt
    13741 ctatgtacca atgataactt ctatgaggaa ttaataattc ttaaattttt tagaaagatt
    13801 ttgacttgaa aatacttgta atataatata taaattaata tactgaataa aatcaatctg
    13861 gagggataat tatgaagtgt acaaacttta ctttcaaagg agaggaaggt ttagatatat
    13921 atacatataa atgggaagat gaaaatataa aaaaaccaaa ggcagttatc caaattgcac
    13981 atggaatggc tgaaactgca caaaggtatg agacttttgc caaggtactt actaaaaatg
    14041 gttatatagt atatatcaat gaccatagag gtcatgggaa aactgcaaag ataatagaaa
    14101 atgttggaca tttagctgaa aaagaaggat ttagatgtct tgtagaggac atgtatactt
    14161 taacaaatat tataaagaaa gaaaatgaag atctgccaat ttatctattt ggacacagca
    14221 tgggttcatt tgcaagtcaa agatatataa tggattacag taataattta tctggtctta
    14281 tactatgtgg ttcaaatgga aagcaaggaa tcattctaaa tcttgctcat ctgataatca
    14341 atcgtgagat taaaaagtat ggaagacgtt ctaaaagtaa taaaataaat aatttgatat
    14401 ttggcggcga aataataaga agaaatgaaa agactaagtt tgactggtta agtagagata
    14461 aagaacaagt tgaaaaatat ataaatgacc cattttgtgg agtagtgtgt agttgtggct
    14521 ttttttatga tttagttcaa gggttaaaag aaattgagga taaagaaaac ttaaaaaaag
    14581 tgccacttga tatacctatt tacataatat ctggagataa agaccccata ggaaaaaatg
    14641 gtaaaggagt cttaagacta agggatagat atataaaatt aggagtaaaa gatgtaactt
    14701 gcaaacttta caaagatgga aggcatgaat tgttgaatga aataaataga gaagaagttt
    14761 ttgaggatat aatttgttgg ttaaataata aaatagaaat attgtaataa aaaaatataa
    14821 tgatatattt actttaaatt tatttatata taatatttga aaagtggatt atgtatatgc
    14881 aaagtagaaa agagagagcc cagaagtgat tttttgctat aatgccattt attgaatagg
    14941 tgggtgttat tataaataaa ttattaacac tcagtattat tatcattgta tatggaattt
    15001 attttattta aaattccttg aaagtttaaa tatagtaagt tgtagtaaag agaaaatata
    15061 aatatttaaa tgctatttaa tgtgaatcta ttaattaggt tatacttaaa cttaattaat
    15121 agattttata tttcaagaca atgagatagg gttttagatt aaaatataac caatggttaa
    15181 attacagaca ttttgttaac tttccctcga tttactagta aatatttttt ttatatactt
    15241 aaattacaac agatgtacta gggaggtata tatgcaaatt aaaataggta aagtcataca
    15301 gtgtcttaga aaagaacgaa atttaactca agaacaatta gcaaagttta taggtgtgtc
    15361 aacaccagca gtatctaagt gggagagtgg aaattcttac ccagatatag aattattgcc
    15421 tttattagca gactttttta atgtgtctat tgataagctt ttaaattaca agattgattt
    15481 aagtgaagaa gaagtaatga aaatttataa agaattagaa tcaggctttg ctagaattga
    15541 aattgattta tcaacagaag aaccaaaaga agaatttaga caagatttag aatctgtaaa
    15601 aaagctttcc aatatgtata tagagaagta tcctaaaagc tatttattga agctaaggat
    15661 atgttcgctg tatcagatgt attcatataa atttggtaag agtgaactta atgacagagt
    15721 aaaagaaaca acgaatattc ttgaagatat agtgagaaat acagatgata tccaaataaa
    15781 agaaacagct cttattatat tatcaaacgc atattgtatg ttggaggatt atgaaaaggc
    15841 agagttgtat ttaaatatga tacataagtc aataggggat acaagtgtta atttagctat
    15901 gatatattta aagcaaaata gacttgaaga agcagaaata ttgcttcaaa ataaattgtt
    15961 tagtaatgta tttaatataa gcatggattg taagggaata attaatgtat acaaaaatca
    16021 atacaaggaa ttaaagaaaa aattggagaa tagaaatttt aataaaaatg caattgagag
    16081 agaaatggag tatataaaaa ataagttgct ggggtatgca aatctttctt tagaaataaa
    16141 aaaaatgctc agtgaagata aaggtgcatt ttttagtatg tatatggatt atatggaatt
    16201 atctctaatt tttttatttt ttaacatgaa agaagaagca aaaaaagctt tatatagtct
    16261 aaaagaaata ttagaaaaat atcctataca tgaaagtttg gatgtaagtc aaatgagatt
    16321 ttttgataag gtagagtcta aaaatttata tacttttaat atatatacaa acttgttaat
    16381 tgtacttaat gatgacagtt ataatgagct tagagaagaa ccaattttta aggatgtaat
    16441 tgaaaagatt ttagatatgg aaaaaatgtt gaaaaataaa gaataagtaa aaatttaata
    16501 taggacttaa agattaatca aattaaaaga aagtgtttca aaataaaaat ttgaatcacc
    16561 ttttttgtcg gtcttaaaca gttatttaga aaaatagagg tttcaaaata gaaatctgaa
    16621 ttatctgtat tattacacaa aaatagaaac ctaaatttat aaaaatagaa taaaatttgt
    16681 tatataaaat gtaattttgt ctataaaatc tcacctgttt tcttaacttt aagcgtgaaa
    16741 aagaggatgt atcatgaatt ttttagttca tgatgcatcc tgctttgtat gaaatccaat
    16801 atatctttat tatttaaaca atggaaaaga gtcttattta tattttgaga catctctttt
    16861 atttaattat gaagttttat acagttcaat aaataggaat tatatttaga aactcatgac
    16921 attatttctt agatagtgat taaatttatc atattccatt ttagataact tttctgggta
    16981 agacattaca atcaggttat gcccattaaa ttttttatgg tatggtggat gaatgtgttc
    17041 ataattattt gtcttatatt ttactctttc atagaacgcc ttgcgataaa ttgaaatctc
    17101 atcaattgga aggtcaattt ctaaaataat agtttttcct ttcttattta aaagctctaa
    17161 cgctctttgc ccatatctat tattgcgaat ttctggaaaa atgcagaaat gttctacata
    17221 gataaagtta tctgtttccc aacataaaat tatgccgaca aactggtttt tatcataaat
    17281 taaattgaat tgatattctt tatttttcaa aatttctgct tgcaaagaag attttctttg
    17341 tttatgaaat gggaaactaa ttttatataa ttccatagcc ttgtaatata atttattttc
    17401 actggttctt aaccgttcaa atttcacttt actcctccta atcacgaaaa ttccaattta
    17461 tttatgagtt cattttacca tagtcagtat ttgcatacaa tgtgttttaa gttgagtgtc
    17521 atttctttct tttatttatg cttatatctc atagtctaag agataattgc ttaagacata
    17581 actaaaaact attatattaa gctttgataa tctaaaaaca gtatatttat ggacttttct
    17641 aggtctaaaa gtaatcttaa taattttaga agttacaaaa aagttacata aatttggaaa
    17701 gctataatat acatatataa tataaggtta aaactgtaat gaataatatt aatttaaaat
    17761 ttgaacatgg aaggagatta ttatggagaa aagagaaaag aggataataa tatcatcttt
    17821 attaagtgta tcaattttaa tgggtttggc aagtatatat tctatattaa ataaagaaga
    17881 cataagttta accgttaaag gtcaagagca aaaagtatct tcctttaaga aaacagttga
    17941 ggaacttttg gatgaacagg gtgtaaagta taattctgaa gataagatta atccaagttt
    18001 agatacagag ttaaaagatg atatgaaaat aaaagttgtt aaggtaacta aaagtaaaaa
    18061 agaagagatt gaaaaaattc catttgatac aaagcatgta aatgatagta atttgttaaa
    18121 aggaaaatct aaagtttatc aagaaggtca agaaggagaa aaaaaactag tctataattt
    18181 aacttaccat gatggcaagt tagtcaaaaa agtcttatca aaagaagtaa tatctaagga
    18241 gccaactaca aaaattataa aatatggaac taaagaaaaa gtactaatag catcaagagg
    18301 agcaaatata agaggaggca aacatatgaa agtggttgcc actgcatatg caggagatac
    18361 aataacatct actggtacaa ctccaagatg gggtgttatt gcagttgacc cacgtgtaat
    18421 accatatgga acaaaagtat atatacctaa actgggtatg acttttgtag cagaagattg
    18481 tggaggtgca attaaaggta atagaataga catttttatg aacagtgaag gaaaagcttc
    18541 aaattgggga aggaaaagta tagatatata tctacattaa attagtgaat agaataactt
    18601 tacttgaagg acaaaaaagt ataaaatatg aattaactaa actgttagat tattcttaaa
    18661 acataaaaat atatctaagg ggggataaga tgaaaatagt ctgcttagga gacagtttaa
    18721 cgtatggatt tggagtatca cgaagtaatt catggacaaa cattgtaaat aaagagactc
    18781 gattagaaat agtaaataag ggtataaatg gtgatacaac aagtggtatg ttagctaggt
    18841 ttaatgaaga tgttgtaaaa aactctcctg atatagtttt tataatgggt ggcaccaatg
    18901 attttattgc tggtgcggga aatgaaatta ttaattctaa tataatggct atggtgcatc
    18961 agtcatattc aaaaaatatt atacctataa taggtatacc attaaaacca gatattccaa
    19021 atgttaggga agattggagt tgttttactg attttaatat agtatctcaa aacttagaat
    19081 catatagtta ttggataaaa aaattttgta tgacatttaa tactaatttc gtagattttt
    19141 attcagaata taataaaaat atggaactag aaggatataa aaaattatat tttgatgggt
    19201 tacatccaac caaagagggt catagaataa tggcagacat ttttattaat tcaattaata
    19261 agtatataga agagttatag attacattaa aatgcttgtt tatgcgtcag ttgcaataaa
    19321 tacatacagt agagaggggt ttattatgga ttatactaaa acttatgaag agtggataaa
    19381 gggttcatat tttgatgaag atacaaagct agagttggag aatataaaaa ataatgaaaa
    19441 agaaatagag gatagattct ataaggattt agaatttggg actgcgggtc ttagaggaat
    19501 aattgaagca ggaacgaata gaataaataa gtacacagtt agaagagcta cttttggatt
    19561 ggcaaactat atattagaaa acacaacaaa agaagaaaca agtagaggag tagtaatagc
    19621 tcatgataat agacacaagt ctagacaatt ctgtatagaa tctgcaaata ctttggcagc
    19681 atgtggtata aaagcatata tatttgatag tttgagaact actccagaat tatcttttgc
    19741 tgttagaagc ttaaatgcaa tcgctggtat agtcataaca gcaagccata atcctccaga
    19801 atataatgga tataaggtat actgggaaga tggagcacaa gttatgccag agattgcaaa
    19861 tgcaataaca gagaaagtaa atagtataca tgattatagt acaataccaa ccttaacgga
    19921 agctaataaa aatttggtag ttttgttgga cgaatcacaa gatactaaat ttatagaagc
    19981 agtaaaaagc caaattataa gaaaagattt agttaaaaat gtaggtaaaa gctttaagat
    20041 agtttataca cctctttgtg gaacagggaa tgttccaata agaagagcat tgaaagaagt
    20101 tggttttgaa aatataattg tagttccaga agaagaaaat ccagacccaa attttgcagg
    20161 gcttgattat ccaaatccag aagagaaaaa agctttaaat agaggtatat tactcgcaaa
    20221 agaaaaagga gcagaccttg taatagcaac tgacccagat tgtgatagag taggtgtagc
    20281 agtaaaaact actacaggtg agtatgcttt acttacagga aatcaaattg gtggtatgct
    20341 gacacattat ataatagaag gattaaaaga aaataataaa ttaaaagaaa atcctacaat
    20401 aataaaaacc atagttacat cagaatttgg agcagatata gctaaagcaa ataatgttga
    20461 tgtattaaat gttcttacag gttttaaatt tattggtgaa aaaataaaat tatttgaaca
    20521 aaataaaaat agaagttatg tatttggata tgaagaaagt tatggttact tagttgggac
    20581 tcatgctaga gataaagatg gtgtagtttc ttcattgtta atatctgaaa tggcagcatt
    20641 ttactattca aaaggtatga gtttatatga tggcttaata gaactttata aaaagtatgg
    20701 atttttcaaa gaacagacta tatctttgac tttaaaaggt atagaaggtg tagaaaagat
    20761 aaaagaaata atatcttatt ttagagaaaa tcaaattgat tatataaata gtattaaagt
    20821 agttgataaa aaagattata aaaatggtat agataatctt cctaaatctg atgttttaaa
    20881 atactttttg gaagatgaat cttgggtagc tataagacca tctggaacag aaccaaaact
    20941 taaattttac atagctgtaa aaggagctag tgatattgaa gcagataaaa agattcaagg
    21001 tttgaaaaag tatatagatg acatggtcga aaaattaaaa taaaatatta ttattttata
    21061 agataatttt gtaataatat ttatttagct gaaaattata atttactttc attgagtaga
    21121 atatggaaat gttagtagaa ttgttatttt cagcttttat ttgtgttatt tttacttaaa
    21181 taattatatt atagaatgaa tctgagtata attaatattg tataatgaaa ttaatttgat
    21241 agaaaagggg atatttatgt ttggtataga taagaaattg attgaatata taattgcaaa
    21301 atccaattac agtgaattaa gttcaaagtc agcagaagta tctttcttct taatgttgtc
    21361 catatttcct tttttaatat ttacaataag ttctatagct tatataccga ttcttcattt
    21421 aaataagtat atagctttgt ttagaaatat gatgccagaa ggtgcttttg ctgtgttatc
    21481 ttcaatcata gtttctgcaa tagacaatag aaacctgaaa tttttagcag tcagttttgt
    21541 acttactatg tggacatttt caagagcagt aaaagctctt attaaaggaa tgaatagagc
    21601 ctataaagtt aaagaaacta ggtctttttt taaaatttta tctatatcat ttttatttac
    21661 aataatgctt ttggtcctta tttttttatc tatgatattt ttagtttatg gggaaaaaat
    21721 aggttatttt atttttaatc ttgtaggatt ggatgagata tttataaaaa tatgggatat
    21781 tctaagatac actgtaggta taataacaat aatagtgata tttacacttt tatataaata
    21841 cactccaaat aaaaagttaa ctattaaaga atctgcgcca ggtgctattt ttgctacttt
    21901 tgcttggttt ttagtatcat ttttatattc ttattataca aattactatg ctaactatga
    21961 agtaatctat ggaagtatag ctgaaataat tgtacttatg acctggatgt attttagtag
    22021 ttggtctatc gttattggct atgaggtaaa ttcaagattg tattttagaa agataagaca
    22081 tgaaatgtta aagtaaagta tttaaaataa aagagagtat ttagtattat aaatgtaatt
    22141 gaattaataa agaaatattg acatttaagt taaaaagtct agaatttttc tgggcttttt
    22201 ttatttttag tataacttga caaattttat ttaatgggat agttttaatt tataatcatc
    22261 tttaaaaaga tgactattga taagtaagag ataaaattgg taagtatcaa aaaatatact
    22321 aaataaaaat tatagtccta atgagttaat ttctgtattt tcaaataatg cagtatttag
    22381 tcatgtgttt ttatatgcgc ctgtatttct aattaccaat atattagaat aagctactgt
    22441 aattagattt agaaaaaagc gacataaata attataaaca aataataaat tacataaaat
    22501 taaatttatt cacaagtata tcttataaaa tatgttataa ttaatagaaa attgtcatat
    22561 aattaattaa gtagtattat tataaataac attgaaaggt agtggttaga atatggatac
    22621 ccataataaa tatgtaaatt ttataaaaaa tatacctgta ccttttttat attgtagaat
    22681 tgtaaagaga caagaagata tagaatatcg agtagaatat ataagtaagg gtatgggcaa
    22741 agtattacaa ttagaagaag gtatttgtga taaaaatata ctagatgtat tgcctgtatt
    22801 taagtctaaa aaatatttca aagagttgtt ctcaaatgaa gtggattgta taaaaaggta
    22861 cattccgaca cttaaaaatt ggataaatat aaaaaaacag ataatagggg attcatacat
    22921 aattttgtat tttggtaaaa ttgtatttga ttatagacag ataatcgatt cctttgataa
    22981 aaaggaaaaa gtagcttata ttaaagacga agaaggcaca tatatagatt gcagtgaaaa
    23041 tttaatacca atattaaata acaacattaa aacaacgaaa gatatctttg gtaaaaatga
    23101 tatagaagta tggggagaga atacaggaaa attatttaga gatgattata gagaaggagt
    23161 atctagtaaa aaaagatttt tacaaaatct ttttgaatat gaagaaacat tttttatggt
    23221 tgaaaaatat tttttgtatg atgaagacga acttttaggt actataggga tagtagacaa
    23281 tataatatat agtggttaca gtaatagaaa ttataactca aaagatttaa tgaagatgat
    23341 agaacactca attccagaga atatgtttta taaagatgtg tatggaaatt atattggatt
    23401 taattcaggt tttttgaatt tagcttgtat gaataaagaa gaattattag ggaagaatag
    23461 ttataaaata tcagaagaag aagctttaat agataagata tttgaaagtg ataagggtgt
    23521 agttgaaaat aaaaaagtag ttacatttga gttaaatata agtatgaatg atgaaaacaa
    23581 gtgtattgag attacaaaaa ggccgttttt tgatagctat ggaagtgtta ttggaataat
    23641 tggaacagca agggatataa gtagaagaaa aagattagaa gaggaaatgg ataaaactag
    23701 gatggaattt tttgcaaatt tatcccatga acttagaacg cctataaact taatatcatc
    23761 ttcattacaa gtgatagaaa aaaaagaagc agatttaata gaatcaaatg atactttaaa
    23821 aagaaattta ggtataataa aacaaaatgg aaatagaata ttaagattag taaataatgt
    23881 tatagatttt acaaaaatgc aatcaggata tttagatttt aaaccagaag aatctgatat
    23941 aattgcattt atagaggaga tatgtatgtc tgtagctgat tttgcaagcc aaaataatat
    24001 acaacttaca tttgatacag aaatagaaga attttcaatg ttatttgatt cagaaaaatt
    24061 ggaaagaata atattaaatt tactttctaa tggaattaag tacaataaga aagatggaaa
    24121 aataaatata tttttatatg tgaaagataa tgtatttaat atgaaaatat ctgatagtgg
    24181 aataggaata ccaaaagaaa aaatagataa aatatttaat aggtttgaac agattgacaa
    24241 tgaactttct tacagagtta aaggaagtgg tattggactt tcattagtga aatctttggt
    24301 tgagttgcat gagggaagta tatctttaaa aagtcaactt ggtattggaa gtgaatttat
    24361 agtttcattg cctgttagaa gtaaaaataa tattgaaaaa tataatcata aaagagaaat
    24421 cagcaatgaa ttaagtaaaa aattagaaat agagttctcg gatttataag tttaaatata
    24481 aaaaataaaa ttttaaaaaa gtattgacaa ttgatttaga agggtttaaa ataaattaca
    24541 acataataaa taaaaaggcg atgaatagga agagtaaatc taattcgatt accagagaga
    24601 agagtccgtt ggctggaaga ctttttaaat tagagggatt gaaaactacc taggagctac
    24661 tttctgaagt catctgcatt agtagatttt agtaagaata gtcgttagct gcgttaaagt
    24721 gtaaagtgag ttttcatgac atatgaaaac taaattaggt ggaaccgcgg gaataatact
    24781 ctcgtcctta tgttataagg atgagagttt tttgttattt aaaaatataa acagtaatca
    24841 taataattat agaaaatata aaagcaatga ataggaagag taaatttaat tcgactatca
    24901 gagaggaaag ttcacaggct gaaagacttt ctaagtttga gaaattgaaa actacctagg
    24961 agctgtggtc tgaagttact ttaaaaagtt ttagtaagac taaccgttaa ctgcgttaaa
    25021 gtgtaaagtg gattttatca ataaatgata aaatcaaatt gggtggaacc gcgagtatag
    25081 actcgtccct ttatataggg atgagtctat ttttattgca ataaaagatt gaaaataaaa
    25141 aaaaatcgga aaattataaa tttaggagga aaataaaatg gagaataaag tgaaaattgg
    25201 agtactagga tatggagttg taggaagtgg acttatagat ataatagata ataataaaga
    25261 aaaaagaaat atagaaatag ttggaatttt agttaataat ttggaaaaac ataaggataa
    25321 aaaatattct aatataataa ctaataatat agatgatata tttaataaag atatagatat
    25381 acttgttgaa gtcatgggtg gtttagaacc atcattatct tatataaaaa aagcattaaa
    25441 caataaaatt catgttgtta cagcaaataa agatttgtta gctgaatgtg gagatgagct
    25501 tgcaaaatta gcaagtgaaa ataaagtaag tattaaattt gaagcttcag ttgcaggagg
    25561 tataccagta ttaaaaccaa taatagaatc actagaagga aataatatag atagtataaa
    25621 tgcaatttta aatggaacta ctaattttat attatctaaa atgtatgatg agaatctatc
    25681 ttatgatatg gcattaagac aagcacaaga attaggtttt gctgaagcaa atccagagtc
    25741 agatgtatta gggtatgatg ctgctagaaa actatcaata ttatcaactc tagcttatga
    25801 caatagagta tattggaaag atgtgtattt agaaggaatt acagatatag atgaaaaaga
    25861 tattgaatat gcaaaaaaat taaattgtaa aataaaattg attggtcaaa gtaagtatga
    25921 aaatgataaa gtaagtgctt ttgttagacc tgttttagta gaaaaagata atatccttgc
    25981 tagaatagac aatgagttca atgctgtcat agtgaatgga gattcagtag gagaagtttc
    26041 ttttgtaggt aaaggagctg gaagtttagc aacaggaagt gcggtttatt cagatgttat
    26101 agatataata gataatagag tttcaagtat agattctttt actaaagata aaatacaagt
    26161 taataaaata gttagagaaa agtgtggagc acttcttaga tttaaaaaat gtaataaaga
    26221 tgaaattcta aatatagttg agaattgttt agtaaaattc gatattttaa atgatgatga
    26281 tgaacttgct attatggttt atgctgattc tgaatatgaa ataaacaaca gtttatgtct
    26341 aataaaagat aaaggatact gcgaaaaaat gaataaaatg ttgaaaataa gttaaaaaag
    26401 aaaaaatata agtttatatg taacatattt tgacgatttt aatactatat agtatgagat
    26461 gaaacaaaac atctcataaa aaaattaaaa ttaaagggag agatatgtta tatggaaaat
    26521 aaaaaatgtt attcagaaga ttggtatgaa agaggagaat ctacagctaa atggttccaa
    26581 aatgatagag aagaatatga aagagaagca tatgatgaag atagagaaag aagaggttca
    26641 aactgtggat gttcagattc aggagaaaat agacctagaa actgtgaaag atttagaaga
    26701 gaagctgaga taagagaaag agaagcaaga gaagcattct gtgaatcttc agagaaaaag
    26761 aaagaggcat tagcatatga atgtgaagct agaaaattat gggaagaagc agaaaaatac
    26821 tgggatgaat attcaaaata caactataaa ggaatcgaat atttagcaga agctgctaga
    26881 ttatttgatg aaggtatgga atgtgaagct agaagaaatg gaaataatgg aggaaacaat
    26941 aataattgtt gccataaatg ccataaatgt aattgtaact gctgtagaaa ataaaaaaat
    27001 taattgacaa atcaatagtt aaaatatatc atattatgta taataaagag aaaattcaga
    27061 aaaaaataat gattagaaga aatataagta tatttattag acaaatagtg ctcagttagt
    27121 gaggtgagta caatatgatt aaactcccat cctctagctt ttgatagagg gtgggagttt
    27181 ttatttattt atatatctta aatgaggata atattgtaaa ataaatgagt atgagattgt
    27241 aaaattagga ggtaaaaatg aaaagtatta aaacatcaag tatgaaagaa aaggtagatg
    27301 aaaagatatt aagagagcaa gtaagttcta taatagaaga tataagaaat aataaggatg
    27361 ttgcacttaa aaaatataat gagaagtttg atagaaatac aagagatgaa tttagaatta
    27421 ctaaggaaga aataaaggaa gcttataagc atgtagatga cgaatttata aataacttaa
    27481 agattgctgc caaaaatata agagaatttg ctaaagctca aaaactaagt tttgaaaacc
    27541 cttttgaaaa agaaatttat ccaggtgtaa tcttaggtca aactaatatt ccaatagagt
    27601 catgtcttgc atatgttcca ggaggtcagt atccattgtt ttcaacagct cttatgctta
    27661 taatacctgc aaaagtagca ggagtaaaaa gaatagtggc atgttcacca actatgaaaa
    27721 atactgaaaa gataaatcct aagacattgg tagctatgga tatagcaggt gctgatgaaa
    27781 tatatgcaac tggaggagtt caagctatag cagcatttac atatggaaca gaaaagatta
    27841 atccagttga cataattgta ggaccaggaa ataagtttgt aactgaagct aaaagacaat
    27901 gttatggaca agtagggatt gattttgtcg ctgggccaag tgaagttctt ataatagcgg
    27961 atgaaacttc aaatccagtt tatattgcag ctgatttatt agcacaatgt gagcatgatt
    28021 taaatgcaag aggaatatta ttgacaaata gcttggaagt agcacaaaaa gttgaaaaaa
    28081 atatagaaag tatgctaaaa gatttgccaa caaaggacat agcatatagt tcatgggaaa
    28141 ataatggaga gataatattg gttgatgata tggaagaagc cattaaaata agtaattttt
    28201 atgcaccaga acatttagaa gttgcagtaa atgagtataa tgatatttgt gatagattaa
    28261 ctaactatgg ttctttattt attggaaatc tttctgctga ggtgtttggt gactatgttt
    28321 caggtaccaa tcatacatta ccaacactta aagcatcaag atatactggt ggtgtttggg
    28381 ttggaacttt tatcaaaact tgtacaaagc agatatttaa tgaaaaagct atacaatcat
    28441 tagcacctgt agctgaaaag ctggcaaaag aagagggatt atatgcacat gcaaaggctg
    28501 ctgaggttag gtttaaaaag tagtaaaaaa ttttattttg gcagtcgaga cttagtatta
    28561 gactgagata aggaaaacgc tgagaacctg aataaatact atattttgtg ggtctcggcg
    28621 cttcttttat atctgtatat aatagaataa tactatctgt gtgtttaaat actaacttaa
    28681 tatttctttt ctaaataatg tttatgaaat agttaatatt tttagttaat acttgaaaaa
    28741 aacttttgct aactgtgcaa attcatctgc atttgtcaat atagcagggt gtcctccctg
    28801 actaaaaatg taaatacttg cttttgaaat aaaagttgcc atttgcttgt actcttcttc
    28861 aagattatga cgacacattt cgtcttcctt acttcctgta aataaaattg gcatttctaa
    28921 tttacacaat tctttatgaa acaaagggcg tttctcgttt gcacattgca atagagcttt
    28981 tgtatcaaga ttaacaacat tctcccaatc ttttccatga caccattcat agaattttcg
    29041 tgcttgaata tcttgctttg atttttccct tccagtgatt agattatcta tgaagttatc
    29101 attaagagta cgtccatcaa agctatctgc tataattgct tcaactaaat cgggacgttc
    29161 taatccagta ttaacagctg cccatgctcc tccacttgtt ccaattaagc caactttacc
    29221 acaattcaaa tgttcaatca gtgctattgt ctgtaaggct tcatcatgcc atatgtcagg
    29281 agaaaattga gaaactctat ccgactgtcc attacctaaa aaatcaatta agatacatct
    29341 aaaattttct gcatataatg gcacaagtgc tttaaacata ttagaagaac cagtattacc
    29401 atgcaggaaa attatcggtt taccttgtcc atattcttta taaaaacaag aattaccttg
    29461 atactgaaaa tatgacatat attttcctcc tttttatttg ttaagttaat tataacaata
    29521 taggtatgaa tgaaaaacct catgttcttt cttagaataa aaatgtgcca cgcataaaac
    29581 gtgacacatt tctaattata aattttgctg tttaagtatt ctttgtatgc ttttctctgt
    29641 caaaaagtat ttctctgata actgcttgat actcattcca ttttggaaat ttatacagat
    29701 ttgagaatta cgagaagcta agacttgttt ggtgtttgtg ttttcacccc aatgcttttt
    29761 gtgctcttgc tttttgggaa tataaatcac tttaccatct atatattctt gcacttgctc
    29821 aatcagttct ttaggcagta agtcaatcga attttgatag ctcattttgc acctcctaaa
    29881 taattattct ttaggattag caaaggctac tgccactcac aattaaaaat aaaatttttt
    29941 attatgtaca atagcctttg ctatgcacaa gttccaattc ccataaacta aatactcctt
    30001 tctggtttga aaaattcatc tgaacattga tttcgctttt aagatagagt tcaatgacaa
    30061 atttacattt ttattatata tattcagata gataattgca actgtctttg tatgaggata
    30121 ttttattata gtcaatacta taatatgtat ttatatcatc aaactaatat gaacagttga
    30181 aaggaatatg aacaataaaa cttagtcagg aagaataatt atgaagcaga caatagagaa
    30241 atttgatttt aaagttttat tgaaaattta ttgacaaatt taacttgtaa atattatact
    30301 aaacttaata aataaagttt ataaagtaag gtgttgtcta tgaaaaatat agttggaaaa
    30361 ccgcaaacga taaaaaaagt aaatgaagat ttaataaaaa acattataaa aaatgaaggt
    30421 cctataacaa aaccagaaat ttcaagcatt actgaattga gtttagctac agttaataag
    30481 attgtagagc aattagcttt gaaaaatgaa gttaaagtaa gtggactaag tgaatctact
    30541 ggaggaagaa gagctcaatt atttgaaata aatgcaaact tagaacacat aatagcttta
    30601 tattattata gaaattgttg tataggggta gttgccaatt tattaggtga aataatttat
    30661 caagaagaat ttaatataag aatggatacg tatgaaaacg ttaaccaaga tacttttttt
    30721 gttatagata ctctaataaa aaaggaaaaa ggaaacaata taagggctat tggaattggt
    30781 gtcccaggag ttgtaaaaaa aggtgtagtt aaaaatatac caactataaa aagttgggaa
    30841 ggtataaatt tagaaaattt aataaagagt aaatacaata ctaaagtgtt tatagaaaat
    30901 gatacaaata ttactactat tgggatttat caaaaacagt ataaagacaa atataaaaat
    30961 atggctctta tgtatttaga agatggtatt ggttcaggta tagttataaa tggtgaattg
    31021 tatttaggtt ctacaaattt tgctggagaa ttaagttatc taaatataga atttggtaag
    31081 tataactcta acaacttaaa tcttgaagat tatattatga gtttaagaaa aagatattta
    31141 gaaagtaaag ataataaatt taagaaagaa attttatcta taatatcaaa ctttataagg
    31201 actcttgtat gtgtcctaaa tccacaagct atgattatac agtgtagtat attaaccaag
    31261 agtgacatgg agtttataga aaaagatgta agcaataatg ttggagaaga aaattttcct
    31321 aaattaataa aagtagactc attgagagaa ggaagtataa atggagtaat tagtatgtgt
    31381 ttaaaagaaa ctgactatca atattcctta tctaataaaa aaggaggata ttaatgtgaa
    31441 atatttggtt tcaatagatg gagggggaac aaaaactaaa ttttgtgtaa gtgacttaga
    31501 tggaaacata cttaaagaac ataccactgg ttcaactaat tataagtcag ttggaattaa
    31561 aaaaacatat gaaaatatta ataatggatt taaaaaaata ttaaaagatt tatatatcga
    31621 ttatgacgat attgagtaca ctgtatttgg tatatctggt tgtgattctc ctaatgatta
    31681 taagattata atggatgaaa tattaaaaat tgggattaac aaagaaaaaa tatatctggc
    31741 aaatgatgca gttttagctt tttatgcaca agctgattcc cctggcttag taattgtggc
    31801 tgggacaggt tcaattatac tgggaattaa agaagatgga gaaatatata gagttggtgg
    31861 atgggggtat aattttagtg atttgggttc tggatatgat atagggagaa aattattaaa
    31921 gaaagtattg ctttattgtg atgaatgtca tgagtatagt gatttattta gttgtgtctt
    31981 ggacttcttt ggagcaaata gttttgaaca acttgcatat atgattactg atataaatga
    32041 taatgttgaa atagcaaact tagcttcatt agtgattgat tgtgccgaac aaggtgataa
    32101 attggctatt gaaatattaa gagaatcatc aactgaacta tctaaattag ctcaagtaat
    32161 attgagaaaa atatctaatc caatgaaaat ggataaaagc gaaataaata tagttttgtc
    32221 tggtggtaca ttaaataaaa ctgtatatgc tcaaatgtta atgaataatt taaaaacaga
    32281 aaatacagat aaaaatttaa aatttatatc tcaagaaaat cagccagtat atggggggat
    32341 aagacttgct atggcattag ctaataggag ggtcaagcat ggatagaaaa aaggtaatag
    32401 tacaaatttt tactggaggt tttaaggcta aagaaataaa gtttaatgat ataaaatgta
    32461 aactactaga attattggac tgtattgata tagaaaaggt tatcatggga tggagtgtag
    32521 atgaagaatt atatgtagaa actaaaaaac tattaaataa atataatgtt gaactatatc
    32581 tttggttgcc atgtttttct gaaataggat tacttgaaaa aagtaattta ctaattgatt
    32641 atatggggaa ggaagtcaag ggctatgctt tacaagagga tgaaaatttt gagttttatt
    32701 gcccaaataa taaggaaaat ataaaaaata taaagaaaat atatagtact tattttagtg
    32761 atattaaatt tgatggaatt tttttagata aaataaggta tggttctttt tcgaataaac
    32821 taaatggtgt ttttaattgt ttttgtaaag attgtttaaa tatatataaa aaaaataata
    32881 ttgataaaga gtcgttaatg agagaaatga ataatgtgtc taagggagtt atagataatg
    32941 aagatactcc atttggtata acagaataca ttaatggaaa atacaaattt aaaaataaaa
    33001 tatgggaaga tttttttgaa acaaaaaatc aaaatatata caaggcatta ttagagataa
    33061 gtagttattt taaaagtaag ggattgaaaa taggtataga tgctttttct ccttttattt
    33121 cttactttac aggtcaagat ttagaaaaat tacaagaagt agcagatttt ataaaaccaa
    33181 tgatgtatag aactacaaaa gctccagctg gtttaccatt tgaatttgaa aggtttattg
    33241 atgaatccat acataagaat aaagagattg gaaaaagaaa tttcttagat attttaggaa
    33301 ttaaggagta tgaaggagat gtatatccta tagaatttgt actagaggaa atcgatttta
    33361 tgacaagaaa tcttaataaa gatatatatg taggagttga aataaataaa aaggaaatta
    33421 tatctcctgt tacacctaag tacataagtg aaaatatttc aaatataaat aagacaacag
    33481 taaaaggata tgttttatct tgggatttgt tgtcagcacc aaaagaaaat attgatgaaa
    33541 ttataaaatg gtttcggaat tagtgaggtg ataaagtgag taagatattg gaaatacaac
    33601 aaatatataa aagttttgga aaggtagatg ttttaaaagg gataaatttt gagttagaaa
    33661 agggagaagt aagagctctt ttgggagcta atggagcagg aaaatctaca cttattaaaa
    33721 ttttaggagg agttcattct caaactaaag gtaaagtaat tttgactggt aatgaaataa
    33781 tgtttaaaaa tccacatcat tctaaagaaa atggtattag tataatttat caagaattaa
    33841 gcttgatacc aacgcttaca gtacttgaaa atatttttct tggtagagaa attttaaaag
    33901 gaagtgtgtt tttaaacaag aaagacatgc ttgaggaata tatgaaaatt tgtgaggatt
    33961 ttgattttaa tatagaccca catatagtag tttctaattt aagtgtagca aaccaacaaa
    34021 tggttgagat aatgaaagct gtttcatgta attctgaaat tatcataatg gatgaaccta
    34081 caacatcact tactaataat gaaaaagatg ggctatttaa aataataagt agactaaagt
    34141 ctaaaggtaa aacaatagtc tatatttctc acatattaga ggaagttttt aaagtatgtg
    34201 atagtgcaag tataatgaaa aatggaatta tgattggaac ttatgatgta gaggatttaa
    34261 ctaaattaaa gataactcaa cttatgacag gaaatgataa tcacaaactt attgagaaga
    34321 aggattatac atttgcaaaa tatgaagagc caccagtact agaagtaaag aatataagct
    34381 ggtctaacaa aataaaaaat gtttcattta aagtttatag aggcgaagtt gtaggtcttg
    34441 caggtcttgt aggttcaaga agaactgaaa ttataaattt gatatttggt atagataata
    34501 aagatagtgg agatattttt atcaatggta aaaaagtaga cataacttct cctaaggttg
    34561 ctataaaaaa caaaatagga ttgattcctg aagatagaaa aaatctagga ttaattttag
    34621 aacaagctat atacacaaac tcatcatcag tacaaattga taaattcaag aaatttttgt
    34681 ttatagatag aaataaagaa attgagtttt ctaaaaaagg tgttaaggaa ttaggaataa
    34741 aagttagtga tgtaaagcaa gaagtaaaag agcttagtgg tggaaatcaa caaaaagtag
    34801 tagtttctaa gtggttagag aaagatttag atttaataat atatgatgag ccaacaaagg
    34861 gaatagatat tgctgcaaaa gaagatattt tcaatacaat caaagaattt tcaagtaaag
    34921 gaataggagt aatatttata tcttctgatt tagaagaagt aataagagta agtgatagaa
    34981 ttttagtaac tagagaaggt tctattgtag atgatttaaa aaatgagaat atacaggttc
    35041 aagatataat gaacagtata tttaatgtat aaaaaatgaa aatggaggac tgagatgaag
    35101 aaagcttttg agaagttaaa tttaagagat tatggagtat tattaggttt tttagcttta
    35161 tgtatagcta taagtattgc aactccatca tttttaggta aacaaaatat acttaatctt
    35221 ttacgacaat cttctataat tggaataatt tcagcaggta tgacttttgt tataatatct
    35281 ggaaactttg atatatcagt tggagcagta gcagctcttg caggtgctat aacaatgaaa
    35341 tttgcgactg gtggaactaa tttgtttgca tccatgttct taggtgtagc gatttgtgca
    35401 gtaataggat taatcaatgg tatagtagtt gcaaagataa atgtaccatc attaatagcc
    35461 actatggcta tggtcactat tgtaagagga ttgctgttga tgcttacagg aggatatcca
    35521 attactgaaa atataccaat acttgattac attggaaatg gatatttgtt taatatacca
    35581 ataccagtag taattttctt tatagtggtg ttagcttcgt ttattgtact taataaaact
    35641 aagtttggta gatatgttta ttctgtagga gggaatcaag aagcaagtaa acttaatggt
    35701 ataaatgtag attctcacaa agtgaaagtg tttattatta atgctgtact tgcaggaata
    35761 gctggaatcg tactaacagg aagacttggg actgcaactg cgattgcagg tgaaggatat
    35821 gatatggatg caattgcatc tgtagtaata ggaggtacat cagtggcagg aggttctggt
    35881 tctgtactta aaactgttat aggagtatta cttatgagtg ttataaacaa cagttttaat
    35941 cttcttggaa tagatgtata tttccagtac atatttaaag gattaataat tttagcagca
    36001 gttggatttg attcttatag caagaaaaaa cttgcttcaa gataaaaaat aagggggatt
    36061 tttttatgaa aaaattaatg aaacatttag cattgttgct atcacttgtt atgatatttg
    36121 gtttagttgg ttgttcaaat ggtggtgaca aagaaaaaaa tggagaaaag aaaatagcag
    36181 tattactacc aggttcaaca ggttactttg tagcaactaa acaaggtata gatgcaaaat
    36241 ctaaagaatt aggtgtaagc gttgaatatg cagatgctca atgggatgct agtaaacaat
    36301 tatcacaagc tgaagatttt atggctaaag gggtagacat gattgcatta tgtggagttg
    36361 attctgctgt aagtgagaga atagttaaag ctgctaatga ttcagacgtt cctatagtag
    36421 catttacaaa ttctatagga agtaacccaa ctggagaatt taaaggttta gttacatata
    36481 taggacaaaa tgaggaagaa acaggagcat taactggaaa aattgctaaa aacttattag
    36541 gagaaactgg tgggaaagct gtattaatag aaggagtacc aggaactact ccacaagtat
    36601 taagaaaaaa aggtcttgaa aaagaattaa aagatagtaa tatagaaata gtttataatc
    36661 aaacttcaaa ttgggagaaa gagcaagctt taaaagtaac agaagattta attcaaaaga
    36721 aaactgattt taatgttata atatgtcaag atgataattc tgctacaggt gcaggtcaag
    36781 ctttaaaaga tgctggtctt aaggataaag ttaaagtcat aggtttgggt ggaagtaaag
    36841 atggattaaa agctataact gatgggttaa tagatggtac aacttatatg tctgctgtag
    36901 aagaaggtgg attagtcata gaaaaggcat ctaaattcct taaaggtgaa aaaatagaac
    36961 ctgttacaca aattaaacaa gttgaagtta acaaagataa tatttcagag ttcaagggtg
    37021 aatggtaaat tgtcatagat aataaataag atttttagag ttactttaga aactatataa
    37081 agtaactctt tttttaattt aatttagtga taaattattg aatagtattt ctaaacaaat
    37141 aaaaaattaa tataaacaaa gacttaatta tactaaatta taagtaaaac taatataaac
    37201 ttatggaaaa aaggaaaacg tctaaagtat tggaattact atagtgtagg tgtagtatta
    37261 aaaaaacata aaaaaacata aaaaaattgt tgaaaaaaat atagaaattt tgtataatta
    37321 aagatttgaa aagtgcggta tacaaagcca attcttttgt atataatata tataaattca
    37381 gaaaaaggaa gggatatgta tggccaggcg gttattttta gaaaggattg gacttatatt
    37441 tttaggttca gcaatattag catttggagt ttataatttt tattatttaa acaacataac
    37501 agaaggtgga gtgttaggta ttttactact gttaaaaaat ttattcaata tacaaccagc
    37561 aatagcaaat gttgtaatag atggtttact acttttagta ggatataaat ttttcggtaa
    37621 aaaattcctt atatattcaa tagtagcttc tataactttt tcagtgttat atgacttatt
    37681 tgaagctata ggacctctag taccacaatc acaaaatatg cttttatcaa ctattttggc
    37741 aggtgtaact gttggaactg gtgtaggtat agtagtaaaa gcaggttgtg catcaggagg
    37801 agacgatgct ttagcattag taatttctaa gactacatct ttgaacatag ggcaagttta
    37861 tttagcaaca gatgttattg tattgttgtt atcattattt tatctatcag cgtttgatat
    37921 cttttattct ttgattgctg ttacaattag tggcaaggta attgatttta tttattatca
    37981 tggtaaaagt ttggatatgg atataagtaa tgatatagtt ccagaatgtt aatataaatt
    38041 aaataacttt agattttatt aggggtggca gatttgccac cttttttgtg tctaaatctt
    38101 tatagaaagt ataatcccat ctaggttttt gcaaatctca aatatagaat tatgttggaa
    38161 tgactgggaa tacgattgct agatgtgcat tttaaaaacc caattttata tttatgaaat
    38221 actaatcatt aatggatgtt tcttaatcct atctttatac ctaaaatgat aagataaatg
    38281 aagtagcaat acaaaactaa aatttgtaaa agagattaaa ttaaatggag gagctaaaat
    38341 gttggatata gttatgatag cattgttatt cataggattt gtttccatga agttacttgc
    38401 tgattggtgt gggaaacaaa ctgaaaaaaa ataatgtaat gtatggaggg attacctatg
    38461 tggtttctgg cagttgtaat tataatgtta ataatatatt tggtatatgc gcttattaat
    38521 cctgaaaaat tttaaacagt ataaggctaa taagtaagtt gaattggggg gaacaatttt
    38581 tatggtgcag atagtaatag tgttagcgat ttttatgatt ttagtaatac ctatgggcaa
    38641 gtatttatat catatagcta ctaatcaaaa aacatttgga gatagactat ttgataaagt
    38701 ggacaatttt atatataagg tatgtagtat agataagaaa aaagaaatga actggaaaca
    38761 gtatgcatta gctttattat ttacaaatgc agttatggta tttataggat atatcatact
    38821 tagaactcaa agtatgcata tttttaatcc aagtggaatt aaaagtatgg aacaaggact
    38881 atcatttaat acaataataa gttttatgac aaatacaaat cttcaacatt attcaggtga
    38941 atcaggactt tcatacttta gtcagatgac agtgataata tatatgatgt ttacatcagc
    39001 tgcaacagga tatgcggctg ctatggcatt tgtaagaggt ctagtcggta aaaagaaaac
    39061 attgggaaat ttttatgtag atttaattag gataacaaca agagtacttt taccaggagc
    39121 tttaattatt gggcttatat tagttacaca aggagtacca caaacttttg ctgggacaga
    39181 aacagtgact actatagaag gaaagcttca agatatagct agaggtcctg tggcagctct
    39241 tgaatcaata aaacatttag gaacaaatgg tggtggattc tttggttcaa attcatcaca
    39301 cccatttgaa aatccaacaa taatatcaaa tatagtagaa atattatcta tgatgatatt
    39361 accaggagct tgtgttgttg catttggtca catgataaag aataaaaaac aaggttgggt
    39421 tgtgtttggc gcaatgtcaa tcatattttt aataggtcta gtagtgtgct ttaaagcaga
    39481 aagtgcagga aatcctattt tatcacaatt agggcttaat caaagtatgg gaagtatgga
    39541 aggtaaggaa gttagatttg gtatagcaca atcatcatta ttcacaacag tgactacttc
    39601 ctttacgaca ggtacagtta ataatatgca tgatacactg actcctttag gaggattagt
    39661 accactttta aatatgatgc taaatgtagt atttggtggt aaaggcgtag gtctgatgaa
    39721 tatgttgatg tacgctataa tagcagtatt cttatgtgga ttaatggtag gaagaacacc
    39781 agagttttta actaagaaaa tcgaaggaaa agaaatgaag cttattgctt tacttattat
    39841 attacatcca cttttaatac taatgttctc tggtctttca gtagcaatac cagcagggct
    39901 tgaaggaatt tcaaatcctg gattccatgg attatcacag gtattgtatg agtttgcatc
    39961 ttcagcagcc aataatggtt caggatttga aggtctagga gataacacta tgttttggaa
    40021 tataacaaca ggtgtagtta tgttctttgg aagatatgtg tctattatag tactactagc
    40081 aatatcaagt ttgttagcat ctaaaaaagc tgtaaatgaa agtataggaa cacttagaac
    40141 ggataatttt acatttacaa tagttttagt acttgttgtt ttaattgttg gtgctttaac
    40201 atttttccca gccttagcgc ttggacctat ttcggagcat ctagtgttgt ggcactaaaa
    40261 aattgggagg gagtaaagtt ttatggaaac taaaaaaaca aagtttatta caaaagatat
    40321 tttcaaaact tccattatag aagcttttaa aaaattaaat cctaaataca tgatgaaaaa
    40381 tccagttatg tttgttgtag aaattggatt tatagtaaca ttgatactta caatagtacc
    40441 tagtttgttt ggtgatgaag gcaataactt aagagcttat aatgggattg taacaataat
    40501 cttatttata acagtccttt ttgcaaattt tgctgaagct gtagctgaag gaagaggtaa
    40561 agctcaagca gatacactta agaaaactag aaaagataca gtagcaaggg ttatagatac
    40621 gttaggaaat gaaaaaatga taagtgcaag tgagctaaaa cttggtgata ttgttttagt
    40681 aaatgctgga gaagttattc caaatgatgg agaagttata gagggtatag cttctgtgga
    40741 tgagtcagca ataactggag aatctgcacc tgtcatgaga gaatcaggtg gagatttcgc
    40801 atctgttaca ggtggtacta cagttgtaag tgactggtta aagataagaa taacaacaaa
    40861 accaggagaa tcgttcttag ataaaatgat agctcttgta gaaggtgctt caagacaaaa
    40921 aacgccaaat gagattgctt taaatacttt attagtaggg ttaacactta tatttatggt
    40981 tgttttaata tctctttatc caatggcaaa ctatgcaggt gtaaagattc caatttctac
    41041 tatgatagct cttttggtat gtttaatacc aactactata ggtggattgt tgtcagctat
    41101 tggtattgca ggtatggata gagtaactag atttaatgta attgcaatgt caggaaaagc
    41161 agtagaagct tgtggagacg ttgatactat gattttggat aagacaggta cgattactta
    41221 tgggaataga cttgcatcag aatttatagc agttggaaat gcagattcaa aagatttaat
    41281 aaattattct gttatgtgtt cattaaaaga tgatacacca gaaggaaaat ctatagttga
    41341 tttaggtatg aaattaggtt caacaggtaa gacaaaagag gcagaggaag ctgagtttgt
    41401 agaattttct gcacaaacta gaatgagtgg tattaactta gctgatggta gagctataag
    41461 aaaaggtgct tatgatagca taataaaaag agtaaaagaa tctggtggta cagtgccaga
    41521 agatttagaa gaaaatgtaa atcgagtagc taaactagga ggaacacctt tagtagtgtg
    41581 tgtagataat gagatatatg gaattatcta cttaaaagat acagtaaaat cagggcttgt
    41641 agaaagattt gctagacttc gagagatagg aataaagaca ataatgtgta caggggataa
    41701 tcccttgaca gcagctacaa ttgcaagaga agctggagta gatggattta ttgcagaatg
    41761 taaaccagaa gataaaatag atgcaataaa aaaagaacaa ttagagggta aaatagttgc
    41821 aatgacaggt gatggaacaa atgatgctcc tgcacttgct caggcagatg taggtcttgc
    41881 aatgaatagt ggtacaacat ctgcaaaaga agcagcaaat atggtagatt tagattcaga
    41941 cccaactaag atattggaag ttgttgaaat aggaaaacag cttttaataa ctcgtggggc
    42001 tttgacaaca tttagtatag caaatgatgt tgcaaaatat tttgcgatta taccagctat
    42061 atttactctt gcaatacctc aaatggagat attaaatgta atgaaacttt ctacgtcatt
    42121 tagtgcgata ttatcagctt taatatttaa tgctataatt atcccatgtt taatacctct
    42181 tgcaatgaag ggagtaaaat atagacctat gaaatcacaa gctatgttaa tgagaaatat
    42241 gcttatattt ggtcttggtg gagttatagt accattttta ggaataaaat taattgattt
    42301 attgattaca cctttagtaa tggttcttaa tttaggttaa taaatggagg atataaaaat
    42361 gaaaacatta aagccagcat tacttgtaag tattgtattg ttagttgttt gtggacttgt
    42421 atatccactt gttttgacag gtgtaagtca agttgcattt aaagataaag ccaatggaag
    42481 tatgatagaa gtaaatggtg taaaagtagg ttcagaactt attggtcaaa gctttacaga
    42541 tgcgagattc tttaagggaa gagtatcatc agtaaactat aatacttata caaaagaaga
    42601 tttagtacca gataaagatg gaaatacatc ttatggaggt gtatcatcag ggtcttttaa
    42661 ttatggagct acaaatccag aacttcatga tagagtacaa aaagatatag aaaagttttt
    42721 aaaggataat ccaactgtca aaagagagga tataccaaca gatttactta cagcatcagg
    42781 ttcaggactt gaccctaata taagtccagc ctctgcaaaa attcagatac cagctatagc
    42841 aaaagcgtct ggaatatcag aaagtaaatt acaaaaaatt gtagatgata atacttccaa
    42901 aaaacttttt ggagttttag gtgaagatag agttaatgta ttaaaagtta atgtagaggt
    42961 cgcaaaaata ttaggtctta tatagtattt tgtggaattt tagcaacaaa atattacgca
    43021 agatttaatt taaaggttaa attttaaaga gtgaaaatcg ataatgattt tcactttttt
    43081 atttgaatat tactaatatt tggaataaag tgattgtaag tataaaatcc aaaaaaaggt
    43141 tgcattatca aaatgataat actataatat atttatcgtt atcaatttga taatagattt
    43201 ggacatatag gaggaaatag tatgttatat aataacgcat tagagttgat aggaaacaca
    43261 cctgtagtaa ggctgaataa tttaggctgt actaatgggt gttctaacat atatgtaaaa
    43321 ttagaaaaag taaatccagc aggaagtata aaagatagag ctgtttatga aatgttagag
    43381 ggcttagagc aaagaggaga attaaaaaag ggagatgtac tagttgaagc aactagtgga
    43441 aatactggta ttgcattatc tatgatagga aaattaaaag gatatgaagt agtaatcgta
    43501 atgcccgaaa caatgagcgt tgagagaaga gatttaatga aggcttatgg agcaaatttg
    43561 gtgcttacag atggtaaagc tggaatggca ggttccatag aaaaagcaaa tgaactttta
    43621 aaagaaaatc caaactataa aagcctaaaa caatttgaaa ataaagataa tccaaatgca
    43681 cattataaaa caacagcagt tgaaattatg aatgatgtca aagatttaga tatattcgta
    43741 tgtggagttg gaacaggtgg tactttaata ggaactgcaa gatatttaaa agaacaaaat
    43801 ccaaatataa gagtaattgc acttgaacca aaaaaatctc cagctatatc agaaaacaag
    43861 actggacctc ataaaataca aggaataggt gctaactttg ttcctgaaaa ttatgattct
    43921 agtgtagttg atgaagtaat attagtagat gatgaagatg catttgatac agttaaatta
    43981 cttgcagcaa aagagggaat tttagtaggg atatcttctg gagcaaatat atttggtgct
    44041 atagagatgg caaaaaagta tccagataaa aagatagtta cagtagctcc agatggagtt
    44101 gataagtata tgtctatggg aatattttaa taattttatt tgagggagtg aatactttgt
    44161 ttaagaaaat aaataaagat attgaatata taatgaagaa tgatccagca gctaggtcta
    44221 agatagaagt ttttttactt tatccatcag ttcatgcaat gataatgcat aggatggctc
    44281 atgctcttta taagaagaag aagcttttta cagcaagatt aatatcccag atatccagat
    44341 ttatgactgg catagaaata catcctggtg ctaaaatggg ggaaggtata ttgatagacc
    44401 atggaatggg tgttgtaatt ggagagacag ctgaagtagg gaatagggtg acaatatatc
    44461 aaggagctac tttaggagct acaggaaaag atactggaaa gagacatcca actgttggtg
    44521 atgatgtatt aattggtgct ggaacaaaaa tactaggacc tttaaatata ggttcaaatt
    44581 caaaaattgg tgcaaattct gttgtcgtta aggatgtacc taatggtgca acagttgttg
    44641 gtataccagc aaaaatagta aaaataagaa acctagaacc tgtaaaaaag aataaaaaag
    44701 aagtgtccta tgagtatgat gaattagata atgtatatta tatataggat ttatataact
    44761 ataaaataaa ctttataaaa attattttaa aaggtatttt tttcaaattt gaggacataa
    44821 taaaaaagaa ctgaatgtta cagttttggt tcatcaatct ttgataaaca agattttaaa
    44881 tttgtagcgt ctaggaggat tttattatga aagcaaatgt taatcaagat acttgtatag
    44941 gttgtggatt atgtccatca atatgtccag aagtatttga tatgaaggat gatgggaaat
    45001 cacatgttat agttgatgaa gtaccaagtg atgctgaaga atcagcagca gaagctagag
    45061 aaagctgtcc agttgatgca atagatgtgc attaataaaa taaatgccta taaaaattga
    45121 attttcaatt tttataggca tttgtctttt attcagttag tatttcaaca cctgtttctg
    45181 taactaaaac catacattcc cattgagcag ataatttacc atcttttgta taaatagtcc
    45241 aattattttc ttcatcaaca aaaatttcgt gagttccttc atttaccata ggttctattg
    45301 tgaatatcat cccaggaacc aatagcatct cagtcccttt tttagataca taacttacaa
    45361 aagggtcttc atgaaagctt aatccaactc catgaccacc tatttctcta acaacagagt
    45421 atccattttt ctttgcataa gagttgatag catcacctat atctcctaaa aatccccatg
    45481 gtttggcaac ttcaagacct ttttggacac attcctttgt aacttgaact aatttttttg
    45541 cattttcatt aacattacct atcataaaca ttcttgaagc atctgaatag tatccattaa
    45601 aaatagtaga aacatctaca tttataatat ctccatcttt taagataatg tctttacttg
    45661 gaataccatg acaaacttca ttatttactg atgtacatac acttttagga aatccattat
    45721 agtctagtgg agcagggata gctccatttt gtagtgtaaa gtcatgaacc aacttattta
    45781 tatcttctgt agacattcca atttcgattt tatctgaaat ataatccaaa atttttgtgt
    45841 ttattacagc actttttttt atttcctcaa tttgactttc attttttata atatcatgag
    45901 ttggtacaat atgacctaac ttagcaaatg aatctatttt attatccata tccatatgac
    45961 attttttata ttttttagta cttccacacc aacagctatc atttctattt aacttcataa
    46021 cttttcatcc ttcttttatt atttatttaa attatgggtt acataaacta ttttaaaaca
    46081 taaccattat aaatattata acataaatac taagaaatcc tttatagata gtgatttatt
    46141 caaagtataa attattatat ggttattgtt gatgaaaaga ggatagttaa atgtattatt
    46201 ggatattagc gcacttaata gtttagttca agtttttcaa gaaaatcata tgttagagga
    46261 caattttcct ttaaagtatt ttttgaatct tcatcaagat aataatgtac aaatgattct
    46321 gcaaaaaatt cttctataaa cttgcttata tatgcatgtg caacttgctt agggtcataa
    46381 agcttatatc tttcctgagc aaatacttcc ataaattctt cagaatttga ttttttattt
    46441 aaaacatttt tatctatagc atgtgcagtt tcatgtaatt ctaaattttt tgatgaatgt
    46501 acatttgcat agctagggtt actataacct attttagcca ctatagaatt atttctatat
    46561 ataccaggta catctttcca agtcttgcct gatcttaccc aacatggagg taattgatat
    46621 tttaaatcac taaattctgg ttcatcagtt agatttgaat ttattaattt tatttttata
    46681 tccttttctt taagtgtctg taaatattta atatttattt ttgcaagtct gtttttcata
    46741 ttttcaactt catctttatc ataattcaag tcatcaggaa gtataagcat ttgttcaatt
    46801 atatctatac tactgtcttt tatattttca gattcttcat caaacttata ttgaagagta
    46861 ttattttcat agatagttat atttgtatta ttttctatag aataagagtg aatatcctct
    46921 aaatctaaaa tattcatttg ttgtaaaata tgttttgttt cgccactcca tactactaaa
    46981 gaaagtgaat taaaattaat tagtggattt tcttttgctt ttatatcatt gcttatatct
    47041 acatcaaata catattcaat tgagtcttct atgttaagac catctgtatt ctttttaata
    47101 tataaatacg cttgttttaa gtctatataa atctcatcta aagattcgtc ataaaattct
    47161 gataaattat tagtaaagag ttcttcactt aaaagttcat ttttatcagt tatactttca
    47221 attaaaatat taatttcttt tatcatatcg taaatactta tttttctatt tgctttttca
    47281 ctagatacat tgcatggcgc aagagcaatg caataaaaat ctttttcttt tttataaaag
    47341 gctttaagtg attttgataa aagtgtaaag tctacaccta tctgtaagtt gaccttaagt
    47401 gagtcatttt gtaataattc agtattattt cttttagctg tatttaaatt gttttccata
    47461 atcattgccc cctttttatt agggtatcat aattttttta tatgtgtcaa tttgtttttt
    47521 tgaaaattat aatttttttg aaaattttat tttttataat ttgtgaattt tttattatag
    47581 aaataaatat gttattatta tgtcaaaatt tagcattaga ttcatgtaga gtatgtttta
    47641 tacatatatt ataattaatt ctttgaagat tgcatattca aaatacacac catttttttt
    47701 aattctataa tataatattt ata
//
LOCUS       DAEHWO010000026        46315 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEHWO010000026 DAEHWO010000000
VERSION     DAEHWO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.026"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(602..988)
                     /locus_tag="KNP54_001718"
     CDS             complement(602..988)
                     /locus_tag="KNP54_001718"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892623.1"
                     /translation="MIDEMKPENKRIRELRLNLNLSQEEFANKLNLKRNTISLIENGK
                     RNASERTLNDICKTWSISEEWLKHGVGEMFFIKELDEQFAHLVGELSKMENEVEREII
                     TKMFKLNKKYLTVFDKMIDSLLEIEE"
     gene            1136..1279
                     /locus_tag="KNP54_001719"
     CDS             1136..1279
                     /locus_tag="KNP54_001719"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892624.1"
                     /translation="MTDINKIREEIYRKLELLGPAKLKLALTKVDILKEIQDIEDENN
                     IQN"
     gene            1257..1508
                     /locus_tag="KNP54_001720"
     CDS             1257..1508
                     /locus_tag="KNP54_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892625.1"
                     /translation="MKIIYKIKGVKRLKISDFNKNQIGSAVQLQDIRFDTKADCIITK
                     VEKNEILVMYYEKETEEIAYKTLTKEDLILDDYKLKLLS"
     gene            1536..2267
                     /locus_tag="KNP54_001721"
     CDS             1536..2267
                     /locus_tag="KNP54_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892626.1"
                     /translation="MDLLKDARKKEWFWLENDLIDREDLSIYEKMIYIVLARYSNEES
                     SCFPSYKTISEKAGCSIRQVSNILNELENKELIIRENRNHEGKKEKNSNLYFLISSKA
                     KVQNEVPNVRHEVPNPMAPGALHVRHEVPSKKTYNKKTYIKSNTTTQKESKTDYLDLS
                     FLDLDIEKVKLTKDEYDKLISKFGKKYIHDKIVSLENYIINGKGSRYKSHYRALLTWG
                     NGDASKGIVPEVTKTKNPLSGFKEL"
     gene            2295..2480
                     /locus_tag="KNP54_001722"
     CDS             2295..2480
                     /locus_tag="KNP54_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892627.1"
                     /translation="MNEKEETVYLNSSNVKLFLGVRDIKEFEELIENVNERICQLQES
                     INKLAQFNIEFDIKSDI"
     gene            2506..2724
                     /locus_tag="KNP54_001723"
     CDS             2506..2724
                     /locus_tag="KNP54_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892628.1"
                     /translation="MKDEKLELTEKDLHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECKDYFTHIDTFIKLSEMTGVDIFTK"
     gene            complement(2743..2955)
                     /locus_tag="KNP54_001724"
     CDS             complement(2743..2955)
                     /locus_tag="KNP54_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892629.1"
                     /translation="MNMCKIKTLREKCSLIDDKVEFSGEYKTFPGFTGSKLLECECNK
                     NYICKIQIMTANSNCPLFKKARQLQY"
     gene            3118..3378
                     /locus_tag="KNP54_001725"
     CDS             3118..3378
                     /locus_tag="KNP54_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892630.1"
                     /translation="MKEEKLELTEKELHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECEGDFTCMYHSFTKLSKITGVKVTAFKYCFPDENPKATI"
     gene            complement(3371..3559)
                     /locus_tag="KNP54_001726"
     CDS             complement(3371..3559)
                     /locus_tag="KNP54_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892631.1"
                     /translation="MSQYRVISKECPVINETISLTCEYSAPPGTFGSKLMSTRCDGSH
                     ICDSSSNEECPILKKLLR"
     gene            3697..4014
                     /locus_tag="KNP54_001727"
     CDS             3697..4014
                     /locus_tag="KNP54_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892632.1"
                     /translation="MERKKHEFTDQDIQRLIEGLRTDPKIREMIFKSKGCETRTSTRS
                     KCEQFVEEKLAYRSYGFETPKYYAKLIADIIDILVYKNVPRDRICGVLYDVERVIPLV
                     VTF"
     gene            4036..5367
                     /locus_tag="KNP54_001728"
     CDS             4036..5367
                     /locus_tag="KNP54_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0892633.1"
                     /translation="MNYSLEAEQNILGSFLINDSIGYKIRELKENDFYFESHKIILSC
                     MKKIIDSNKPLDLLLLKNELEKIDRLVDIGGVSYITSLTTIVITTSNIDHYIKIIKEK
                     LLKRQISELANELINNSNSDTSIDELIIDINDLKALVTTSSSVNDNYIDASKIKREKG
                     VHKSIDTGFNKLNNMLDGFRYGTLTILTGKPASGKSTIVNQFIAQAITNGEKAFLYSG
                     ELPSFMSMDWFRKTVANDYHIKEYKSVYGGTYTDIPDYAVELISDWIEDKFFLYDEDA
                     ISDEVNLLNTIEHLYLKKGVRFFVLDNLMTIKTGNKADKYERQEQIVSNLKNLAKKYN
                     LVIVLVAHPRKNMGDMKPTMYDVSGASEIVNYADYILSTYRVVDEEEETDDTYLLILK
                     NRITGKQNISFKMNFSERRKRLYTTSEELNRDYKYDVNKQYVQVEIPEDVF"
     gene            5742..6128
                     /locus_tag="KNP54_001729"
     CDS             5742..6128
                     /locus_tag="KNP54_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892634.1"
                     /translation="MIALEKFAGGVLKEKFNTELQKVLDNIADPNTDFKKTRKISLEI
                     VFKANEDRDLAEVDIKSKATIVEAKATTTKVLIGKDLETGRVEASEFKNQVAGQLVMD
                     IPDSEETNETEENSAGVIDFRNASSK"
     gene            6181..6885
                     /locus_tag="KNP54_001730"
     CDS             6181..6885
                     /locus_tag="KNP54_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892635.1"
                     /translation="MIRNAMEYLVKLGKRETVCVDGFKYTTDALEIIKEPKANELEIT
                     TLSGLVDYIKSGIDHKADELLLIQVLTPRKVLLKSPLRKNRDRETYIECVALLPEKRF
                     DRPLDLDSFNIMLQSAFIKNNDRDTLLKIAGNIQESTVKNVGDDGVSQSVTIKTGVAS
                     VSEAIVPNRVKLIPYRTFQEIEQPESEFIFRMSSGPAAGLYEADGGAWKNQAMLNIKA
                     YLQEELKDFKNVNIIA"
     gene            6942..7124
                     /locus_tag="KNP54_001731"
     CDS             6942..7124
                     /locus_tag="KNP54_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892636.1"
                     /translation="MKMISHMNILERAEFTDKIANAIMSANKEIERGCAFNEAVEIVK
                     QMEYRENKYNEGDIAI"
     gene            7121..7498
                     /gene="ssb"
                     /locus_tag="KNP54_001732"
     CDS             7121..7498
                     /gene="ssb"
                     /locus_tag="KNP54_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBF0892637.1"
                     /translation="MNNVVLVGRLARDPELRYIPEYGTPVATFALAVDRGYTKKDGTR
                     EVDFIPIEVMGGSAEFCANYLAKGRMVSIQGQIRIEKYEKDGEKKTFTKVRTKIVNAL
                     DRKPKDEEKEISFQVLDDEDIPF"
     gene            7479..8063
                     /locus_tag="KNP54_001733"
     CDS             7479..8063
                     /locus_tag="KNP54_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0892638.1"
                     /translation="MKIFHFKLDGDYVRSLEERNKLVEENINFVWFIIRRYFKVFISK
                     YPYLQDDTFSEGCIGLCKAADYFDSKKGIEFTTFAAVCIKGQIFKFISRYVKKHYRAD
                     IDSFEKCIYKNTHGEEIRIEDRLAGNENVDIENVHVIRSCIKRSKIEDIQKITYLREK
                     GYTQKEIGKILRTNQMTICRKLGKLKSEINILGK"
     gene            8093..8251
                     /locus_tag="KNP54_001734"
     CDS             8093..8251
                     /locus_tag="KNP54_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892639.1"
                     /translation="MKTKIIGGRENQCPLCNGSVFKIETSIGIVWQCKDCGCMYQDMN
                     CKENKRRH"
     gene            8254..8580
                     /locus_tag="KNP54_001735"
     CDS             8254..8580
                     /locus_tag="KNP54_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892640.1"
                     /translation="MACVIKCDFCGETIAEILNIKVFRIDDEGNIMSIGKDVCDKCYD
                     RLFRSNLNKKMTNYEKIKNMSKIEMAEFLANGGSGCTSCAYDFQECLGGCLEGRKKWL
                     ESEAMK"
     gene            8580..9116
                     /locus_tag="KNP54_001736"
     CDS             8580..9116
                     /locus_tag="KNP54_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HBF0892641.1"
                     /translation="MKKTLIIVGVVISILIMFACLFLVTKNKAIDLEEQVQSATASVE
                     VQEKRRIDLIKNIVDCVKDYAKYENRTLKEVTDMRVSANDESIKEAKLNIQAVAEKYP
                     DLKANENYKQLMSELSITENMIAQHRENYNMQVRNYNKYIRKFPANLILNSMGYEKIE
                     SKYTEYKAKEDAPQNLFD"
     gene            9128..9934
                     /locus_tag="KNP54_001737"
     CDS             9128..9934
                     /locus_tag="KNP54_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892642.1"
                     /translation="MKFKTFEITKREFLVSIIIACMMIVLGFFIDDKVQSKFLEDNER
                     YYKATKINNDKDLFDYAMETSAGDSLISGRFKSVDSVSIEELKGDYWFIERTEEKYTM
                     HTRVVTTKDSKGHSHKYTETYWTWDYHDSIEKKCNKFNFMGKEFDAKVITNLSKERLA
                     LKKDIFKNNNLKIKGNYAYINNKRRYYYEVIPKEFNGTMYANLKNNTIANPADKNIKV
                     FKGESIQNVLENNNFNTGFFKVVFWIIWILITTIIIYVFYYLKNDWLEDK"
     gene            9959..10219
                     /locus_tag="KNP54_001738"
     CDS             9959..10219
                     /locus_tag="KNP54_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892643.1"
                     /translation="MKCKVYHAIKNIKDANELIDRFETENIFFELNDIDNENVLNGEM
                     NLTDIEDIASLQFILDGDLFIFSSCDEMIFMNKYTQKELGLQ"
     gene            10243..10728
                     /locus_tag="KNP54_001739"
     CDS             10243..10728
                     /locus_tag="KNP54_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892644.1"
                     /translation="MDLKLISSIPNWKVEDQLAKIDEEVTEFKNAIDTGITKDIIAEG
                     LDVCQTILTMFQVLEIENYITEGVETHNKKLNGRGWDLKEIGDDILNLIKNSMINELI
                     NMNKKLKCLDEKEFNAKIQFLDVDKLWNLCMPLVNLSTIKGVNESIDEMKMGEFLKNI
                     N"
     gene            10748..11005
                     /locus_tag="KNP54_001740"
     CDS             10748..11005
                     /locus_tag="KNP54_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892645.1"
                     /translation="MLIEVTENNRELKVGDIVEINGGNKLYMILSLKETIGGYVIINM
                     QNGYGSFGAYKSLSQLELDLKVRGYKLYSSDDYKLQLVPRE"
     gene            11114..11557
                     /locus_tag="KNP54_001741"
     CDS             11114..11557
                     /locus_tag="KNP54_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma"
                     /protein_id="HBF0892646.1"
                     /translation="MQSSKKDNLFSSAEGKLYDYKKIKAEIEKIDIDMQMIKNDYRGC
                     SGVEIKEKTGKTYDIKSVIEIETEEKEKKIALKEKEKRHKELIIEKIDNAMKILSEEE
                     KKIVQYKYFSSSRTSWEYVGRMIGFSASKCKQMRFDIIDKIKGLL"
     gene            11700..12245
                     /locus_tag="KNP54_001742"
     CDS             11700..12245
                     /locus_tag="KNP54_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892647.1"
                     /translation="MAWNLRSKSFLLSREVLKIKRDITEEISSAAYVPDNLKYYDNVM
                     KETPGMYGRECSLDFIKKKQEKLLKLKKKVKKNYDSNINKIDSYLKILEKSIIDESDH
                     VELVVFKLYLQLENVVKVTETVNDLGFRIKTNTYARERKYSTNDITSIITDPFTDVVE
                     DLKILVQERQRKNYYGNKECF"
     gene            12249..12893
                     /locus_tag="KNP54_001743"
     CDS             12249..12893
                     /locus_tag="KNP54_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0892648.1"
                     /translation="MEAHSGQKVNPIKDIEDVFRLLNFLEEWNERNYLLALFGMCTGL
                     RVGDILALKVADVTDLKLDKKGNKIRVSKDWIRVIEEKRDYNREVFLSDVIKSAIENY
                     TQDKPGEEFLFKSGKRKKFNRPIQTRQAGRIIKGAAKKVGIKENVATHSLRKTFARHI
                     YDEEENKTYALELIRKILGHKTIEMTRRYIGIDKDEEVKAITKFTNKLKKRKRN"
     gene            13108..13566
                     /locus_tag="KNP54_001744"
     CDS             13108..13566
                     /locus_tag="KNP54_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892649.1"
                     /translation="MDVNEVEIIDSSYEKGKELTEDQCNMVTLLITGATVTETARIIG
                     VNRKTIYNWMNKEHVRKEMDRRKQELTNQGNLMILKDLDSYINNIKELASDKSDKRVM
                     LAANQYLINRIYGTPTSTVIQAEDNSVGMGMDATEIEAAIAKIRIRTSKK"
     gene            14121..15860
                     /locus_tag="KNP54_001745"
     CDS             14121..15860
                     /locus_tag="KNP54_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892650.1"
                     /translation="MDNLERNIQLIFSYLAKTFIRNGASIKDAEKEANEIIKANSNNL
                     WGVNGLAYQLGKINLEFFCMYFMQDTYLPKEDNAAAPIAKVHHELWEDIQESIIGDGS
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLICSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGRKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKRFSDDVKYAAQKPVIRNGKTIKRGTTFIALGTLQHKECF
                     YSRLKNLPTWKFKCEKGVLVDNVDELFNSGLWLKFKEILFDFKNTNHLEDAKEFYWEN
                     EKEMKFPILWPSFWDCLDMALSYYENPTSFKQEVQNDVNSIGEKWFKTVRTETREEIE
                     SHTFKKTMLLCDPASAGGSKHDYSAFLVGSESENGLLYGRLAELAKINARTDFDKYID
                     HMIYLLKVYSDITHIYIEKNTFNGADANQLEFKIKNDNVLSYRDIEIINEQQKKNKDD
                     KISTLIPVLSKGQMIFAEEDKEFIQQILDFTGQKYSLHDDAPDISSEFINRINNIKVS
                     ETVNIFDRKLLGF"
     gene            15861..16064
                     /locus_tag="KNP54_001746"
     CDS             15861..16064
                     /locus_tag="KNP54_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892651.1"
                     /translation="MGGNLLANRSKFEEVQKTLTKKGKKFNVGIGKDEKGYFAYTHRA
                     RSKSYISKQDIPIKVLKFIESTG"
     gene            16077..17354
                     /locus_tag="KNP54_001747"
     CDS             16077..17354
                     /locus_tag="KNP54_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBF0892652.1"
                     /translation="MELDLDLIKDIYDDWNSNKSEYDTMYKYYKGETDAISNYKMVTK
                     RSNNKINTNFLKKFINEEVAYSLANKITYTSRSGDEKIINDLEYYTCHWSKKHDSDLL
                     RYALLFGLCYELYYVKDDEIQVKIIKPTDGCHYENENGEIVCFIREFTKGFEDDTYVD
                     VYDKEYIYHFDSNFKEVESPTVNNIFDGNVPISICKRSEELGKNTIFNDIKGLQDAYE
                     TNLSDISNEISDFRNAYLTFSGCNIKEDDLPRMKELGILQVNGDGKIEWLIKDMNDTF
                     VQNTLSSIKENMYEITSHINHNEKMQSNTSSLAVIARLISTEWICSQNNDSIADTLFN
                     RYKLLCIWLNKKYGFDYDYKDIKAKFTPKIPRDDLVVANILSQLGDKLSTETGLSQLS
                     FIDNPHAEIEKAKKEQEIVSEGEILLDESKDYN"
     gene            17332..18093
                     /locus_tag="KNP54_001748"
     CDS             17332..18093
                     /locus_tag="KNP54_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBF0892653.1"
                     /translation="MNQKIITKLTEDIYKSAENRTKPFYKYQRENRDKLLLEIAKILL
                     THDIINEYLNINNKDKKNLRSKLNKIINEYSNSYDEEVKDIETILSDSSKNKYSNLII
                     LLGVILKIKDVSNINNKVINKIVNNKVDGKHWSDRLWKNKKGIEESLKKEIKSFLNGK
                     TSVNKIEKAIRDKYSTGAGQTSRLIENEVARCQSEVNEYFFKVQGIIKVMYCADLDSR
                     TCSDCSMHNGVIFYVNEDRPSLPRHCHCRCQYIPV"
     gene            18152..18478
                     /locus_tag="KNP54_001749"
     CDS             18152..18478
                     /locus_tag="KNP54_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892654.1"
                     /translation="MKVEILGTEYLVIEKLESEDVLLKERAGYCDHSVKEIVIEKINS
                     EEGSLKDLSVYKNEVARHEIIHAFLSESGLKSCSSWATNEEMIDFFAIQFPKIVKVMD
                     KIECLN"
     gene            18504..19106
                     /locus_tag="KNP54_001750"
     CDS             18504..19106
                     /locus_tag="KNP54_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBF0892655.1"
                     /translation="MLKKEVLELLKEIEDDAEIDSLLQSTDLFKSASDKKLTIEEFRE
                     LINNDANFKAIIDNEKNKYHSEALENFKKKDMQTLISAEVLKRTGANETEEQKAIREL
                     RESLDKLKKEKQYAEKVSKYKDILVEKKIPTNLIEYLLSDDDDKTNANIEIFENSMKQ
                     YVQSKVDERIKDGSYVPPGKDSAGSLSEIRKQIKQGLNSL"
     gene            19135..20058
                     /locus_tag="KNP54_001751"
     CDS             19135..20058
                     /locus_tag="KNP54_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892656.1"
                     /translation="MANVLQYVTLFQQELDMQVTVGSTTGWMEKNAGQVIYNGGREVK
                     VPKVTMDGLGDYDRSKGYTQGAVTLEYETMKMEMDRGRTFMLDSMDVNESNFVINASS
                     VMGLFQKQHVIPEIDAYRYSKIFSETAKVDERVKYSYEATVTTILSELKNQLASIQDL
                     SGDIPLIISMSSIIASILEQSSQLDDIEFGDGDIKRIVKSIDNVPIIKVPSKRMKTEY
                     VFRDGKTSGQTEGGFTEGAKALDINWLITPASAPIAVSKTDKPRIFTPDQNQTADAYQ
                     IDYRKYHDLWILDEYLKLCRASVRQAKAAQE"
     gene            20072..20344
                     /locus_tag="KNP54_001752"
     CDS             20072..20344
                     /locus_tag="KNP54_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892657.1"
                     /translation="MFALIKNNIIKVVEDENSRDKLISKGFKIYSEEVTKENIEKKEE
                     KVKSTSNDLFNLSKPELMEIAKGKNIKGYSTKTKEELIQLLDEYNA"
     gene            20328..20708
                     /locus_tag="KNP54_001753"
     CDS             20328..20708
                     /locus_tag="KNP54_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBF0892658.1"
                     /translation="MSTMLDNVKLVLGIENDRYDKLIILYINKISEMVLEYCSRQELS
                     TALEGFVEEKVISILSSRFEELKKNSGLDNLEKSLKAITRGDTKIEYNALTLQTAENS
                     ISSSSFLTDTDKKFLSPFCIVSMY"
     gene            20720..21067
                     /locus_tag="KNP54_001754"
     CDS             20720..21067
                     /locus_tag="KNP54_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892659.1"
                     /translation="MTEADILEMTYLDKMTIIRKLKGWNEETCSNDFSNVVIAENIPC
                     AISRKEEAIVNGDIGSIVVNRKLFCRPEVDIKIGDTINTTYNHGEEAVFKVSKANIYP
                     SHMEIPITELERI"
     gene            21067..21423
                     /locus_tag="KNP54_001755"
     CDS             21067..21423
                     /locus_tag="KNP54_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBF0892660.1"
                     /translation="MGIDNLGVFEALALDLGLNASNFNRKIKKFTKETGQELAENIRD
                     ETPVKTEKLKKGWEEKQPEYDTYIVKNEVDYATLVNNGHSTKNGGIVPGSFMVEKGIE
                     RTKENMTSAKANLFDW"
     gene            21432..21881
                     /locus_tag="KNP54_001756"
     CDS             21432..21881
                     /locus_tag="KNP54_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892661.1"
                     /translation="MLTNRDIIIAVNKRIENEFRYIDIFINEDNIQGFEEACFFVQLL
                     PVSNNIANKVLDTKKIFIDIEYYQKARKNKLNLYDIQSRLEKIFNRNIRVKDRSLIIE
                     NISPSIAKDPVGYKLTFLMTVSYFEEVYFENETFEIMESVDLEIGSD"
     gene            21882..22937
                     /locus_tag="KNP54_001757"
     CDS             21882..22937
                     /locus_tag="KNP54_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBF0892662.1"
                     /translation="MGLPEINISFIQAGKTFVKRSGGIVALILKDTKNIGLVEIKEIE
                     DIPENYSAANLDYIKMAMKGNVYPPNKVLVYTLDTDESIDDALDFLETCEFNYLCMPD
                     ETEQDLPKIKTWIKKMREDNKIKVKAITASNSADYEGIINFTATDIEVEGKKYTSNEF
                     LPRIAGFIAGTPSTQSVTYAEIPEVTNIPKLTRAEANTRINNGELILIKESGAIVIAR
                     GVTSFTTITDSKGDIFKKIKLVDTLDQIHNDIKKIIVKNYIGKTQNTYDNKCLLIVAI
                     QLYLQELEKDGLIDEGSTVEINLDAQRAWLKKQNIDISNMEEQQIKEYNTDTLVFLKA
                     RIKLIDAMEDVYLDISM"
     gene            22953..23393
                     /locus_tag="KNP54_001758"
     CDS             22953..23393
                     /locus_tag="KNP54_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBF0892663.1"
                     /translation="MKAKIDAKRIISGTFGECWLDNKQLTSTKGMEAKVDIDKEEIKL
                     CGQIMTTYKMIGATGKGSITLYKISTLFGEYVEKMLNEGKEFKVTIISKLQDPDSYGS
                     ERIALYGCMFDDLTLADWEAAKVGEIEVPFTFEGFEYLDKIKEK"
     gene            23408..23824
                     /locus_tag="KNP54_001759"
     CDS             23408..23824
                     /locus_tag="KNP54_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBF0892664.1"
                     /translation="MNTVEKLLNMDAGKLKMPSSAFELYCKKLDDTLEIECKAIDPER
                     FDEIRMNSMDVNSGDVENINIYELKVNTILESCSIFSNMELVKKFSAITPKELIKKLL
                     LSGEIDKLYEEVNKVNGIDAEGDKKRQKERAKDIKN"
     gene            23851..24000
                     /locus_tag="KNP54_001760"
     CDS             23851..24000
                     /locus_tag="KNP54_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892665.1"
                     /translation="MYLLFKYKGIMPSVSYHILRGEKEIVSVFMDQELDERKEEIKSG
                     VGRLF"
     gene            24004..27393
                     /locus_tag="KNP54_001761"
     CDS             24004..27393
                     /locus_tag="KNP54_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBF0892666.1"
                     /translation="MSSNTKVLQAIIKMRDEASSTLKRVAANTRALHDSSSQASRALN
                     NVQSNLKSVGTSALKAGGLITAGVGGAFAAATKVGTEFESAMSQVKATFGNSLKPGDF
                     EALSKAARDAGKATTKTAADSANALQYMGLAGWDVQKSMHALMPVLNLSEAASMDLGL
                     ASDLVTDSMSSMCLEVDKVSKSGKVLAGAGLSEYLDKVANASTKSNTSIQQLMEAFNV
                     AGGTFSNLKVPLSEATAIMGILANRGVKGTDAGHALNSIMVNLTTGAGQAGKAMKKLG
                     VSAFDNQGKFKGMSNVLKEVANKTKGMTDEQKNYYLSAIGGKTQLKTLQKLLDGVGNE
                     YDSLKKKIDNSKGALKTMSDVMKDNTKGGLATLKSALEETGITIYYQLKPAIASVVDN
                     LTKMTVWFNNLSEPIKRVITNVMLSVGAFGVLLLTIGAVSLIVSKAIGIFGFFVPIIL
                     RAKVAFRAFVIGMKPLSAVFLAVMGPVGWTITAVIALSVAFTIAYAKSEVFRNKVNSL
                     VKSFTEFAKPIVNFCMPALKQLGEKFKELLSAFGPLFASILNLGSVIMKVLGPVLIGV
                     IGFHIAKLVLILSTLATAFKAVVDTITNVLNGLASILNGVFDLIIGIVTGDSKKMMDG
                     VKQIFDGGTKIIKSIWKGFIDFVTAPIQAIADIADSLFKDKAKWLTDKWRDLRTFLEN
                     PIEATAKISTKTNVNIPGSKAADAAGKSTPNTGGLKQTVANLKGSFSDFKTFIKPMTD
                     SISQGVESGKTKFTELQNKILNDVKPALKVLEDSGVNFKDKFKESITSIKDKFNELKN
                     ILAGNIKTNIDNLVKAFEPLKPHLDNLKDCFDKVKKAITDFFTPAKQVGDTVNKVSQP
                     MDSVKKSTDGIKLSFQSLTQALAPVKAWFQGFMPFLSQIGQQLLPSIGIAIAGVVGGI
                     ILAFTWVLNTLTAIITTVSGIINGIMSFISGIINVIMGLITGNADQTMDGLKQIFDSG
                     VGVIKSIWNGLVDLVSGVLEPVIDLADSLFKDKVKGVKEAWNKLKDFFKHPIKGTIEI
                     FKKGPSLQIGKGADAAGKSPRKAFGINRVPRNDYLIRAHEGEKLLTKQEANQYKRNSS
                     NGSLFLDKLADTIIVREEADIDKIVRKINKKISLAKIGGVL"
     gene            27440..27916
                     /locus_tag="KNP54_001762"
     CDS             27440..27916
                     /locus_tag="KNP54_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBF0892667.1"
                     /translation="MNKKILVLTISIILSLSLVGCSTNNSKNRDSKSKQNTEEVKNHK
                     IGEVVDLDGAKVSVKNIRKLETNSNDYAVEIEITNTGDNDLQSDYLENYILKSSDNTT
                     GEAINNQELNGELMFDTIRPGDTLKGEIAFELTKDATPKTLEIAYENVGKYTVFDL"
     gene            27974..28609
                     /locus_tag="KNP54_001763"
     CDS             27974..28609
                     /locus_tag="KNP54_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBF0892668.1"
                     /translation="MEIWLRQANNTFRFPVIPPSFEINGSATINTSNILSVGDIAVFG
                     GLGLKTIELSSFFPNQEYSFCNYNGFPKPYDCVNLIESWMKEGYILRFIITETNINFE
                     CIIADFNYREQDYSRDIYFTLSLKEYRRIQISKVNINNDEKLSSEKNVPLTKGFDTKQ
                     KTHKVVEGDTLFKIAKKYYSNGDLWEKIYKANEDEIKDPSVIKNGWVLIIP"
     gene            28850..30367
                     /locus_tag="KNP54_001764"
     CDS             28850..30367
                     /locus_tag="KNP54_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBF0892669.1"
                     /translation="MIIDRSKDSSNNNIDFTAKDMGFLLLQSEVSYNFKDKLVEDIAK
                     QVFVDNKFPLGNLPKTNVKYTKMFIGVTGYDTIMSVYTEASKTTKKKYMIESNLDKFN
                     VIEKGVVTLNITFEEGFNLINTNFSESIENVKNKVLVVDQYGNKISEKINDSIFKDVG
                     VIMQKVIQQQENSTIDIDGEFKGIEKTCSLKGYGDITCVTGRGVKVKDSYTKLIGLFY
                     IDTDKHTWQNGDYQIELELNFENIMDEKSAGQDEQKEDGSEYTGGTEYPAEFTAYCPR
                     KEEGGNTDCRGKKLDPSKKTCAAPMVGAYEKSYYTKDFLNKHPLMRYGDEIQLVTGVS
                     SRDGTYKVNDNGPAIIIEKDGTYHIDILFGNVEEANNFGRRKGKIIIGGYSGNMTEKA
                     KTVISEARKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVNLPRTSSQQSKVGKKVEK
                     NNLQAGDLVFFHNPVSHVGLYVGNGEFLHAPQTGDVVKISKLSNRKDFNTARRVL"
     gene            30381..30713
                     /locus_tag="KNP54_001765"
     CDS             30381..30713
                     /locus_tag="KNP54_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBF0892670.1"
                     /translation="MADPINEFIGIIRQEGKFHNEPSFFIGKIKSKLPDLKIEINNII
                     LEKEDILIDSWMLDRQIELFDTETSQEHKHEIKNPFIDTFESGNTVIMFKIGEKFAVV
                     SKLVSLDE"
     gene            30706..31140
                     /locus_tag="KNP54_001766"
     CDS             30706..31140
                     /locus_tag="KNP54_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBF0892671.1"
                     /translation="MNNTIFPFMGVPEDYISPDNEELPIFKEFAWDFNKDEKIIENGD
                     FKIVERNEAIKVWIYKTIKTDKYVHLIYDWSYGTDIKNLIGQKYTKGLTESEAKRYIQ
                     EALLTNPYILEVNITNAEFEDDNLSISLNVKTIYGEEEITFV"
     gene            31133..32185
                     /locus_tag="KNP54_001767"
     CDS             31133..32185
                     /locus_tag="KNP54_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBF0892672.1"
                     /translation="MYNGQSFSTLNNRTLNNINLPLYKGQGSSLYNIVSPINSELAQL
                     YIELSYIHKRVFIQDNFDDFLDRRVNEFGVYRKLGTEAIGEVTFEGKIGTQIPNGTII
                     SHSDLLFVIIKDITIDENSKLNVSPIQALEIGIKYNLSANTEFKLIEEITGVTKIYNE
                     LDLKGGTEIETDEELKERFYKIQKNQATSGNKAHYQSWALEVEGVYNAKVIPRWDGPG
                     TIKILIYGQNNQSVDNEVLQRCTEHIEEEKPIGPTVTIVTPSTFDINISATLTLENGY
                     DIESIKVVFLDIINSYLIENSREIVYIKVMSLLASIEGIHDIKNLLVNGDVKNIIVDE
                     EKVPAVSSAIFDIEVS"
     gene            32187..32795
                     /locus_tag="KNP54_001768"
     CDS             32187..32795
                     /locus_tag="KNP54_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBF0892673.1"
                     /translation="MKLIDYLPSFANNEIDIQIQEALENELLTLIDEKDDLLEQFFID
                     TATWGLDDWENLLSIKVNYKLDFDTRRSNIKAKMRGKGTTTIEVIKAISEAYTKTNVD
                     VEVFSNLFSFTLSFITNNCSYNTILELDKKIEEIKPAHLEHKFERILFNKNELYTGAA
                     ISTGETVTIYPYVPRNLESFGEIAICSGNDRALEKVTLYPKK"
     gene            32812..33594
                     /locus_tag="KNP54_001769"
     CDS             32812..33594
                     /locus_tag="KNP54_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBF0892674.1"
                     /translation="MTEQQYFTLVTDIGKAAIANASITGEKVDFAKIKVGDGGGSSYT
                     PNESQTALKNVVWESTLEHAQGDKDNPNWVVIQKFIPGDVGGFEIREVGLFDSKDQLL
                     AISSYPTTYKPTADSGTVKELLIKVILVVSNVANINLKVDPTVILATLKDIQELDTKI
                     DTTKTELTSNIETAKTELNTKIGDTTQLTTTDKTNIVSALNEVKTSVDSIETTADKTS
                     IKDTDNLFESDNVEGALKEVMQEVKGNRSSIISTINSNLIPM"
     gene            34190..34678
                     /locus_tag="KNP54_001770"
                     /pseudo
     CDS             34190..34678
                     /locus_tag="KNP54_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893144.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            35080..35427
                     /locus_tag="KNP54_001771"
     CDS             35080..35427
                     /locus_tag="KNP54_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892675.1"
                     /translation="MNRNNRIIYDQTGKIWLQTGEAIGDIQELSEITELNFIDVEFGS
                     IDYSKQYIESINPVTKELNIKNIEVVLTDEQKRLEVLEKELNMLKEENKNRDSEIVNT
                     AFEVGNIKLNNNL"
     gene            35439..35609
                     /locus_tag="KNP54_001772"
     CDS             35439..35609
                     /locus_tag="KNP54_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892676.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKMDVFYAVNRITEEQYLELTGL
                     LNKEETPVEPTI"
     gene            35639..35920
                     /locus_tag="KNP54_001773"
                     /pseudo
     CDS             35639..35920
                     /locus_tag="KNP54_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36228..36695
                     /locus_tag="KNP54_001774"
     CDS             36228..36695
                     /locus_tag="KNP54_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBF0892677.1"
                     /translation="MSKSYFNTKLGGSMNVTIVFLATNIFIKLVILAIAFDTLLGCLR
                     AIKTHQFNSSFGINGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLG
                     ISEFFSILFILYESVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGK"
     gene            36699..37529
                     /locus_tag="KNP54_001775"
     CDS             36699..37529
                     /locus_tag="KNP54_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0892678.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADIFRKE
                     GHKVDVIICPEKQFKTKSEEKSYKIPRVNAGGYDLLIELHLNASDRQGKGSEVLYYSN
                     KGLEYATRICKKLGTVFKNRGAKLDKSLYILNSSKPTAILIESFFCDNKEDYEKAKKL
                     GYEGMAKLIVEGVLNKSIESNEVKQMYKHTIVYSGDDRVSADILGLYYKRAKESYLVI
                     DIKDYKPHRTQNLYVIGGVTCNKMKEMSKTTGEKFTQLYGNDVWSTMDKVIEFVKEKL
                     "
     gene            37601..38707
                     /locus_tag="KNP54_001776"
     CDS             37601..38707
                     /locus_tag="KNP54_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBF0892679.1"
                     /translation="MLTFLDLFAGIGGFRLAMERAGHKCVGHCEYDKFANLSYKAMHN
                     PKEDEWFEKDIREIRAENIPKADVWCFGFPCQDISIAGNKLGFKGNRSSLFFSVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNRGFDFAKLLIELDEIGYNAEWQNLNSKNFRVPQN
                     RDRIYIVGHLRRRSTREVFPITGTSRKTTLEQLNNPNHSSNRIYNSNGLSKCLLSKGG
                     NNTGLYRVGNINPSGNGAGGQVYSSEGFSPTLTTGKGESPKILIKENTKKGYIKASIG
                     DGIRLDHIEGKTGRGRVQHKKSCTLTTASNAGVIGKKFRVRRLTPKECFRLQGFPDDY
                     YDRAASVCSETQLYKQAGNSVTVDVVEEIAKKLK"
     gene            38845..39180
                     /locus_tag="KNP54_001777"
                     /pseudo
     CDS             38845..39180
                     /locus_tag="KNP54_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894425.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(39191..39706)
                     /locus_tag="KNP54_001778"
     CDS             complement(39191..39706)
                     /locus_tag="KNP54_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892680.1"
                     /translation="MTWSDLKEKNINEVVDCINNKLSEFESLKKVGDELGANESTIRK
                     WLNKKGYKRTGNKFVEDNKSYDDKYHIDSISSKIDDDIKYLSSEIDNIKNVLEWFKTK
                     DDSYHICVIKENDISIDLPDQSIKRTTVRINNTVWEMFNKFADENKHYDKHDLLSQLL
                     LESLLKYVKSR"
     gene            complement(39789..40694)
                     /locus_tag="KNP54_001779"
     CDS             complement(39789..40694)
                     /locus_tag="KNP54_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBF0892681.1"
                     /translation="MSKLGIDIGNYAVKTSTDDIFESKVTEVKNFGSDSDSIKIGNKT
                     YYLGEGDEEINIVKYEKENFLPLLLGAICRNTDDEIVDLGLGLPVKQFAGLRKNLIEK
                     LQGKEYHVEFTRGNETTKRDITIRSIQTFPEGVTGYLYYAKDIVDQIAGRDVVLVDIG
                     GKTTDIALVQGNKATDPYSINVGTINIYDAIKKSLEMDERFLGKVEIKREKIQDYINK
                     GFYLNGEKQDIKKNIDASISLFKEIYNELKLNYPVSTAAVVVMGGGAKLLGEAFKKNI
                     PGIIVMSDVDKHVFANAKGYKKMMK"
     gene            complement(40714..40917)
                     /locus_tag="KNP54_001780"
     CDS             complement(40714..40917)
                     /locus_tag="KNP54_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892682.1"
                     /translation="MSRIVLTFKNNDKEKAIEKFLDEKLSATAYLKELVWEKMQEKKD
                     NAVVEQKKEIEDPANNFDFGSLE"
     gene            complement(41166..41624)
                     /locus_tag="KNP54_001781"
     CDS             complement(41166..41624)
                     /locus_tag="KNP54_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892683.1"
                     /translation="MKKTIALLLTLCAVMIPFTAFADGNDYEGTGNSQTVELIGQPNS
                     DSPSTKSVVVPGGTANLTAMSGGQLSWRVTSTLGNILGFEGNIDVYKAGKIVSSQYVG
                     FRLAGTTKTGVVTFKGLKKGSYIAKFKGKGVCTGGIILFSSPAEASFTIR"
     gene            complement(41659..41961)
                     /locus_tag="KNP54_001782"
     CDS             complement(41659..41961)
                     /locus_tag="KNP54_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892684.1"
                     /translation="MEVNLHTGKDEFFKSHEVAKNYIGGLYKLIDVYKFSMESVSVLT
                     RIDLDKLNNFYAGEASLNYDELCLIESVIITPLVGAFETAEHNYNMIIKARKERKL"
     gene            complement(42349..42501)
                     /locus_tag="KNP54_001783"
     CDS             complement(42349..42501)
                     /locus_tag="KNP54_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892685.1"
                     /translation="MDNFLFNVLASLTASVVVYLISELFKKAKSHSRAKSDLQVEFKF
                     IFKFKK"
     gene            complement(42621..43355)
                     /locus_tag="KNP54_001784"
     CDS             complement(42621..43355)
                     /locus_tag="KNP54_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBF0892686.1"
                     /translation="MYYVYKYINLDTEECLYVGKTENICDRHASHLSNKKENWCNKNL
                     RFEYIELDNKYTMDFYEIYLINKLEPKFNITGKGEMDIAKTSFSYNGQWVIYSERDLM
                     SSLASKRCGINYEVNAKMLGIMRKLKKISSNEEIFIGNENIRIKYYFETVLEGINLEP
                     CILSVAYKTLKESTVGTVISVKREYLSENVCLIIDSIFLNEIMKDPLMSKSDIKDLNS
                     QVNDILKIIGVDCEWNKLSDYCSANS"
     gene            complement(43375..44562)
                     /locus_tag="KNP54_001785"
     CDS             complement(43375..44562)
                     /locus_tag="KNP54_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBF0892687.1"
                     /translation="MEKKEILMQPNNLIKSKYDFTNVENKLFYKILFNAQKQQNSSYV
                     TTISKEELKVFMKNNNDYEHKNIKEILNMFQQSVLEFDYIEETTGKLKTFGSGLINTY
                     ELDHTDQIYTIMMHEVLYNHITDFVKMQKKKNGYTAINLSVLFNFRGAYTQRLYTLFR
                     LWSRENKEVEIKYKLDELRFYLKLKDNVYPEYKYFKQNVLKRAMNEINKKGNMVVSIK
                     EEKRKNRKIDEIIFSVIDYEPRKYFDKDILVEDYIPKKKQDNEVSFSFYIPNENIFTT
                     GTIKLFKEDFKEFDFKKDVYLNAFNKSIAIAFERDNTDIINTKNYDFFKSTLSNKISE
                     VIIHQKDDLKFKEELDKYWDDEDVKKEEREVDYSKDPVRLETVRRNLFDQGLVNEEGY
                     YYK"
     gene            44982..45671
                     /locus_tag="KNP54_001786"
     CDS             44982..45671
                     /locus_tag="KNP54_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBF0892688.1"
                     /translation="MLENRKQIQKEIYLPIATYCLKDKQYYIKEYGALLIKSAENSDI
                     FNTHKNRILYKNKLDIQEIANELNVNKATIQRNIKKLEKLDFKILKIENTLNGIVYCL
                     PSENNIDLNKFALINYEMLKKMVNKFKSNTIKVYFLLKTITTETNFKPATNSFIAENI
                     GLSSKSKNNLDIITSSVKTLEENKYIETKKVNVYEYDKEKLREVPKIRKVYRICNFDE
                     WKKEIDKNKVY"
     gene            complement(45820..46203)
                     /locus_tag="KNP54_001787"
     CDS             complement(45820..46203)
                     /locus_tag="KNP54_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0892689.1"
                     /translation="MKIKKIPESELLVMMFIWDSEDKEVASTEILKTLGEKYEWKKST
                     MLTFLRRLVGRGFLEVVKKDRFTYYKALIEKEEYLKVETKSFFSFFHKNSFESFISAL
                     HDDEEVSENKLKSLEKFIEDWEEDK"
BASE COUNT        18598 a         5392 c         7721 g        14604 t
ORIGIN      
        1 aaaaaaaaat taagcaggag taaaaaaaat aaaatattat caaaatttat caatataaaa
       61 agaaatataa gtataaattt ttctctttgt atattgattg tatacaattc tatttttgta
      121 aaattaaatt ttaaaaaata atcaaaaatg gtaaattttg acatttgctt aatgtcaaat
      181 taggtgttac aattgtagca taaagaagat atatatcgaa ataatacata taaaactacg
      241 tacgtaaaat atttttaaaa ataatcaaaa atcttaattt tcaatattga atacaattaa
      301 attttcaaac tcatctaggg catgacatac aaaagcaaaa aacattaatt tagtatctga
      361 taaaaattta aaaattgtaa aagggggaag tctgttattt ttcagaagca atgtaattgt
      421 aaaaatataa atcagaatat tttgaaaata tgggggataa acttatgatg gatttagaaa
      481 aggaaaaaca tgaaataatt gaaattataa aaaaattaaa tattgataaa gataaaagga
      541 atttattgat gataaaaaat tatatccttg gacttttaaa aaaatagaag aatagcaatt
      601 gctattcttc tatttctagt aaggaatcta tcattttatc aaatacagtc agatattttt
      661 tattcaattt gaacatttta gttataattt ctctttctac ttcattttcc attttactta
      721 gttcaccaac aagatgggca aattgctcat ctaattcttt gataaaaaac atctctccaa
      781 ctccatgctt aagccattct tcagatatgc tccaagtctt gcaaatgtcg ttcaaagttc
      841 tttcgcttgc atttctttta ccattttcaa ttaaagatat tgtgtttctt tttaaattta
      901 gtttattagc aaactcttct tggcttaaat tgagatttaa tcttagttct cttattcttt
      961 tgttttctgg tttcatttca tctatcatta ttatccctcc atatgaaata ttatatttta
     1021 aaagtgctta caagtcaaca aaaataaaag aaaaaggtat tacaaaatag ttgacttgta
     1081 agcagacatg taatataatt gtattacaca atcaacaaaa gcgaggtgat tgaaaatgac
     1141 tgatataaat aaaattagag aagaaatata tagaaaattg gagttacttg gccctgcaaa
     1201 actaaaatta gcattgacta aagtagatat attaaaagaa atacaagaca ttgaagatga
     1261 aaataatata caaaattaaa ggggtgaaaa gattgaaaat ctcagatttt aataaaaatc
     1321 aaataggatc agcagttcaa ttacaagata taaggtttga tacaaaagct gattgcatca
     1381 ttacgaaagt agaaaagaat gaaatactag tcatgtatta tgaaaaagaa acagaggaaa
     1441 tagcatataa aactttgact aaagaagatc taatacttga tgactataaa cttaagttat
     1501 tatcttaaag taatttcaga agggaggtga taactttgga tcttttgaag gatgcaagaa
     1561 aaaaagagtg gttttggctg gaaaatgatt tgattgatag agaagatttg agcatctatg
     1621 aaaaaatgat ttacattgtc ttagctagat atagtaacga agaaagttct tgtttcccaa
     1681 gttataaaac aatatcagaa aaagcaggtt gcagtataag gcaagtatct aatattttga
     1741 atgaattaga gaataaggaa ctaataataa gagaaaatcg taaccacgaa ggcaaaaaag
     1801 agaaaaacag taacttatat ttcttaatat cttcaaaagc aaaggtacag aatgaagtgc
     1861 ctaacgttag gcatgaggtg cctaacccta tggcaccagg tgccttacat gttaggcatg
     1921 aggtgcctag taaaaagact tataataaaa agacttatat aaaaagtaat accactacac
     1981 aaaaagaatc taaaactgat tatttagacc tatcattctt ggacttagat atagaaaaag
     2041 taaaactaac taaagatgaa tatgacaaac ttataagcaa gtttgggaag aaatacatac
     2101 acgataaaat tgttagttta gaaaactata tcataaatgg taaagggagt aggtataaga
     2161 gccactatag ggctttgctg acttggggga atggagatgc tagtaaaggt atagtaccag
     2221 aagttacaaa gactaagaat cctcttagtg gatttaaaga actttaaaaa ctaaatagta
     2281 aggaggtaga taggatgaat gaaaaagaag agactgttta tttgaatagt tctaatgtga
     2341 agttattctt aggcgttagg gatattaagg aatttgagga attgatagaa aatgtcaatg
     2401 agcgaatttg tcaactccaa gaatcgatta ataaacttgc ccaatttaat attgagttcg
     2461 atattaagtc agatatttag ttaagtataa attaggaggt tgcctatgaa agatgaaaag
     2521 ttagaactta ctgaaaaaga tttacactgt attgcaagac atttacaaaa tgaagttatg
     2581 gagatggtgt ttagagggaa tatagaagcc cctacatcat gcgaagtttg cgattacttg
     2641 caagaatgca aggactattt cacccatata gacactttta taaaattaag tgaaatgaca
     2701 ggtgtagata tttttactaa ataaatttag taaattaaaa ttttagtatt gtaattgacg
     2761 tgctttttta aaaagaggac agttgctatt agcagtcatt atttgaattt tgcaaatgta
     2821 atttttatta cattcgcatt ctaaaagttt tgatccagtg aatccaggaa aagttttata
     2881 ttcaccagaa aattcaactt tatcgtcaat aagagagcat ttttctctta aggttttaat
     2941 tttgcacata ttcatcacca ccctataatt aatttgaaca tactgtcaat atgctccgat
     3001 taattataac atgcaaatta tcatgatgta gaattaaagc ataggtcaat taaatttagt
     3061 tataaaatca atgaaacaga taaataatta aatgttaaat aaattagggg gttgttcatg
     3121 aaagaggaaa agttagaact tactgaaaaa gaattgcatt gtattgcaag acatttgcaa
     3181 aatgaagtta tggagatggt gtttagaggg aatatagaag cccccacatc atgtgaagtt
     3241 tgcgattacc tgcaagaatg tgagggagat tttacctgta tgtatcattc ttttactaaa
     3301 ttaagcaaaa taacaggtgt aaaagtgact gcatttaagt attgttttcc agatgaaaat
     3361 cccaaagcta ctatctaaga agttttttta gaataggaca ttcttcatta gaagaagagt
     3421 cgcaaatatg acttccatca catctagttg acattaactt agatccaaaa gtacctggag
     3481 gagctgaata ttcgcaagta agagaaatgg tttcgtttat tacaggacat tctttgctta
     3541 taactcgata ttggctcata ctctcaccac ctttctaatt aatttaaaca tattggaagt
     3601 atgtttaaat taattatagc atgtaaatta tcatggtgta gaatagtttc aaatcaaaag
     3661 aagcaactaa atagttaaag acaggaggta tgctaagtgg aaagaaaaaa acatgaattt
     3721 acagatcaag atatacaaag acttattgaa ggattaagaa ctgatccaaa aataagagaa
     3781 atgatattta aaagtaaagg ttgtgaaact agaacaagta caagaagtaa atgcgaacaa
     3841 tttgttgaag aaaaacttgc ttatagaagt tatggatttg aaactccaaa atactatgca
     3901 aaacttattg ccgacataat tgatatttta gtttacaaaa atgttccaag agatcgtatt
     3961 tgtggggtat tgtatgacgt cgaaagggtg attcctttag ttgtgacatt ttaataataa
     4021 gctgggggtg attaaatgaa ttactcttta gaagcagagc aaaacattct aggaagtttt
     4081 cttataaatg actctatagg ttacaaaata agggaattaa aagaaaatga tttctacttt
     4141 gagtcacata aaattatttt atcttgcatg aagaaaataa ttgactcaaa taaaccacta
     4201 gatcttttgc ttttaaaaaa tgaattagaa aaaatagata gattagtaga tattggaggc
     4261 gttagttaca ttaccagttt aacaactata gttataacta cttcaaacat agatcactat
     4321 ataaaaatca taaaagagaa gttacttaaa agacaaattt cagagttagc aaatgaatta
     4381 attaataatt caaattcaga tacaagtata gatgaattga ttatagatat aaacgattta
     4441 aaagcacttg tgacgacgag cagtagtgta aatgataatt acattgacgc atcaaaaata
     4501 aaacgtgaaa aaggcgtaca caagtccata gacacgggtt ttaataaact aaacaatatg
     4561 ctagatggat ttagatatgg aactcttaca attttaactg gtaaacctgc atctggtaaa
     4621 tcaactatag ttaaccagtt tatagcacaa gcaattacga atggagagaa agcatttttg
     4681 tattctggag aattaccctc tttcatgtct atggattggt ttagaaaaac tgtagctaat
     4741 gattatcaca taaaagaata taaaagtgtc tatggaggaa catacacaga tattccagat
     4801 tacgccgttg agcttatatc agactggata gaagataaat tttttctcta tgatgaagat
     4861 gcaataagtg atgaagtaaa tctactaaat accatagagc atttatattt aaaaaaaggg
     4921 gttaggttct ttgttcttga caatctaatg acaataaaaa ctggcaataa ggcagataaa
     4981 tatgagagac aagagcagat agtaagcaac ttaaaaaatc tcgctaaaaa atataactta
     5041 gtaatagttt tagttgcaca tcctcgtaaa aatatgggtg acatgaagcc aactatgtat
     5101 gatgtgtctg gagcaagtga gattgttaat tatgcagatt atattttatc aacttacaga
     5161 gttgttgatg aagaagaaga gacagacgac acttatttat taattttaaa aaatagaata
     5221 acaggaaaac agaatataag ttttaaaatg aatttttcag aaagaagaaa aagactttac
     5281 acgactagtg aggagttaaa cagagattac aaatatgatg taaataaaca atatgttcaa
     5341 gtagaaattc cagaagatgt attttaaaaa aagtataaaa aataggaaat tttattaagt
     5401 aatgatttta taagaaaaac caatattgaa taatttaaaa attcaatatt gaaaaaaatc
     5461 atttttcaat attgaaaaac ggattttgaa aaagtattga atttcaatac taaaaaaagt
     5521 ttgaaaatat agcatttaca aggtttatat aaattaattt cctgacaatg tacacacagg
     5581 tttagatatg ctagcaaaaa aacttaaaag tagtgtaagg ataaaaaggc tatataaatt
     5641 tataaaaaga tttaaaagtg ttattaaatt agagctaaag tttattaatt aatttcctcg
     5701 tagaaaaata ttattttaaa taaataaagg agtgatttta catgatagca ttagaaaaat
     5761 ttgcaggtgg agttctaaaa gaaaagttta atacagagtt acaaaaagtt ttagataaca
     5821 ttgcagatcc aaatacagat tttaaaaaaa caagaaaaat tagtttagag atagtgttta
     5881 aagcaaatga agatagagat cttgctgaag tagatataaa atccaaagca actatagtag
     5941 aagcaaaggc tacaacaact aaagttctga taggaaaaga tttagagaca ggaagagttg
     6001 aagcgtctga atttaaaaat caagtagcag ggcagttggt catggatatt ccagatagtg
     6061 aagaaactaa tgaaacagaa gaaaatagtg ctggtgtaat tgatttcaga aatgcaagtt
     6121 caaagtagtt taagaaagta agtaaaatat aaatttaaat aaaaaaggag aataaaaaaa
     6181 atgataagaa atgcaatgga atatttagtt aagttaggaa aaagagaaac agtatgtgta
     6241 gatgggttta agtacacaac agatgcatta gaaataataa aagaaccaaa agctaatgaa
     6301 ttagaaataa ctacattgag tggtttagta gattatataa aaagtggcat agatcataag
     6361 gcagatgagt tgttattaat acaagttcta actccaagaa aagtgctttt aaaatctcct
     6421 ttgagaaaaa atagagatag agagacatat attgaatgtg ttgcactact accagagaaa
     6481 agatttgaca gacctttaga cttagatagt tttaacataa tgctacaatc agcatttata
     6541 aagaataatg atagagatac acttttaaaa attgcaggaa atatccaaga atctacagta
     6601 aaaaatgtgg gagatgatgg agtttctcag tctgtaacaa taaaaacagg cgtagctagt
     6661 gtatcagaag caatagtccc aaacagagta aagttaattc cttatcgcac tttccaagag
     6721 atagagcaac cagaaagtga gtttattttc agaatgagtt ctggaccagc agcaggatta
     6781 tatgaagcag atggtggagc atggaaaaat caagcaatgt taaacattaa agcgtacttg
     6841 caagaagaat taaaagattt taaaaatgta aatataattg cttaattgaa aatctaagag
     6901 ggcttacaat aagtcctctt agtaaaaaag gaggggatta gatgaaaatg atttctcata
     6961 tgaacatttt agaaagagca gaatttacag ataaaatagc taatgcaatc atgtctgcaa
     7021 ataaagaaat tgaaagaggc tgtgccttta atgaagcagt tgagattgta aaacaaatgg
     7081 aatatagaga aaataaatac aatgaaggag atattgcaat atgaataatg tagttttagt
     7141 tggaagatta gcaagagatc cagaattaag atatatacca gagtatggta ctccagttgc
     7201 tacttttgca ttggcagttg ataggggtta tacaaaaaag gatggaacta gagaagtcga
     7261 ttttatacca attgaagtta tgggaggatc cgcagaattt tgtgctaatt atctcgcaaa
     7321 aggaagaatg gtttcaattc aaggccaaat aaggatagaa aaatatgaaa aagatggaga
     7381 gaaaaaaact ttcacaaaag taagaacaaa aattgttaat gcgcttgatc gcaagccaaa
     7441 ggatgaagaa aaagaaatta gttttcaagt tttagatgat gaagatattc cattttaaat
     7501 tggatggtga ttatgtgaga agtttagagg agagaaataa attagttgaa gaaaatataa
     7561 attttgtatg gtttattata agaagatatt tcaaagtatt tatttcaaaa tatccatatc
     7621 ttcaagatga tacattttca gaaggatgta ttggattatg taaagcagca gattattttg
     7681 atagtaaaaa aggtattgaa tttaccactt ttgcagctgt gtgtataaaa ggtcaaatat
     7741 ttaaatttat aagtaggtat gttaaaaaac attacagagc agatatagat agttttgaaa
     7801 aatgcatcta taaaaatact catggtgaag aaataagaat agaagataga ttggctggta
     7861 atgaaaatgt agatatagaa aatgttcatg ttattagatc ttgtataaaa agaagtaaaa
     7921 tagaagatat acagaaaata acatacttaa gggaaaaagg atacactcaa aaagaaatag
     7981 gcaaaatact taggactaac caaatgacaa tatgcaggaa gcttggaaaa ttaaaatctg
     8041 aaattaatat actaggaaaa taatataata atttaagttc attggaggca aaatgaagac
     8101 taaaataatt ggtggtaggg aaaatcagtg cccactttgt aatggtagtg tatttaagat
     8161 tgaaacatca attggaatag tatggcaatg taaggattgt ggatgtatgt atcaagatat
     8221 gaattgtaaa gaaaacaaaa ggaggcatta agtatggctt gtgttataaa gtgtgatttt
     8281 tgtggtgaaa caatagcaga aattctaaac ataaaggtat tcagaattga tgatgaaggt
     8341 aatataatga gtatcggaaa agatgtatgt gacaaatgtt atgacagatt atttagaagt
     8401 aacttgaata agaagatgac taattatgaa aagataaaaa atatgagcaa aatagaaatg
     8461 gctgaatttc ttgcaaatgg cggaagtgga tgtactagtt gtgcttatga ttttcaagaa
     8521 tgcttaggcg gatgtttaga aggtagaaaa aaatggcttg aaagtgaggc gatgaaataa
     8581 tgaaaaagac gttaataatc gtaggagtag ttatttcaat attaattatg tttgcttgct
     8641 tgttcttagt aactaaaaat aaagcaattg atttagaaga gcaggttcaa tcagcaactg
     8701 catctgtaga ggtgcaagaa aaaaggagaa ttgatttaat taagaacata gtagactgtg
     8761 taaaagacta tgctaaatat gaaaatagaa cattaaaaga agtaactgac atgagagtaa
     8821 gtgcaaatga tgaatctatc aaggaagcaa aattaaatat acaagcagta gcagagaagt
     8881 acccagattt aaaagctaat gaaaattata agcaactaat gagtgagttg agtataacag
     8941 aaaatatgat tgcacaacat agagaaaatt ataatatgca agttcgcaat tacaataaat
     9001 atataagaaa atttccagca aatttaattc taaatagtat gggatatgaa aaaatagaat
     9061 ctaaatatac tgaatataaa gcaaaagagg atgcacctca aaatttattt gattaagagg
     9121 tgcacatatg aaatttaaaa cttttgaaat aactaagaga gaatttttag tgagcataat
     9181 aattgcttgc atgatgattg tgcttggatt tttcattgat gataaagttc aatcaaaatt
     9241 tttagaagat aatgaaagat attacaaagc aactaaaata aataatgaca aagatctctt
     9301 tgattatgct atggaaacaa gtgcgggaga ttctttgata agtggaagat ttaaaagtgt
     9361 agattctgta tctatagaag aattaaaagg ggactattgg tttatagaaa gaacggaaga
     9421 aaaatacact atgcatacta gagtggttac cactaaagac agtaaaggcc attcacataa
     9481 atatactgaa acatattgga cttgggatta ccatgattca atagagaaaa aatgtaataa
     9541 atttaatttc atgggtaaag agtttgatgc gaaagtaatt actaatttat ctaaagagag
     9601 attggcatta aagaaagata tatttaaaaa taataatctt aaaataaaag gtaattatgc
     9661 ttacattaat aataagagaa ggtactatta tgaagttata ccgaaagaat ttaatggtac
     9721 tatgtatgct aatttaaaaa ataatactat agcgaatcca gctgataaaa acataaaagt
     9781 ttttaagggt gagtctatac agaatgtttt agaaaataat aattttaata cagggttttt
     9841 taaagtagtg ttttggatca tctggatatt aataactaca atcattatat atgtatttta
     9901 ttatttaaaa aatgattggc ttgaagataa ataaagatgt aagaggagaa gatcaggtat
     9961 gaaatgtaag gtgtaccatg ctattaaaaa tataaaagat gcaaatgagt taattgatag
    10021 atttgaaacg gaaaatatat tctttgaatt aaatgacata gataatgaaa atgtcttaaa
    10081 tggagaaatg aatttaactg atatagaaga tattgcatca ttgcaattta tattagatgg
    10141 agatttattt atatttagta gttgtgatga aatgatattt atgaataaat acactcaaaa
    10201 agagttggga cttcaataaa tgaatgaggg gagatactaa agatggattt aaagttaatt
    10261 agcagtatac ctaattggaa ggtagaagat cagttggcaa aaattgatga agaggtaact
    10321 gagtttaaaa atgctataga tacaggaata actaaagata taattgcaga aggattagat
    10381 gtttgtcaaa ctattttaac aatgtttcaa gttttagaaa tagaaaacta tattactgaa
    10441 ggagtagaga cacataataa gaaactaaat ggaagaggat gggatctcaa agaaatagga
    10501 gacgatatac ttaatttaat taaaaattca atgattaatg aattgattaa tatgaacaag
    10561 aaattaaaat gccttgatga aaaagaattt aatgcaaaaa tacaattttt agatgtagat
    10621 aaactatgga atttgtgcat gcctttagtt aacttaagta ctataaaagg agttaatgaa
    10681 agcattgatg aaatgaaaat gggagagttt ctaaaaaata ttaattaaag taaggagata
    10741 atataatatg ttgatagaag taactgaaaa taatagagaa ttaaaagtag gagatattgt
    10801 tgaaattaat ggtggtaata agttatatat gattctttct ttaaaggaaa caataggtgg
    10861 gtatgttatt ataaatatgc agaatggata tggttcattt ggtgcttata aaagtttaag
    10921 tcaactagaa ttagacttga aggtaagagg ttataaatta tatagttctg atgattacaa
    10981 gttgcaatta gtgcctagag aataagatat atttcaaaaa agaaaaaaag gagcattact
    11041 tcacgctcct gcttgtcaaa attctaaaac cgtcatcaca acatcattat aacataatta
    11101 ggagtgtgag gtaatgcaat ctagtaaaaa agacaatttg tttagtagtg cagaaggtaa
    11161 gttatatgat tataaaaaaa taaaagcgga aatagaaaaa atagacattg atatgcagat
    11221 gataaaaaac gactacagag gatgtagtgg agttgaaatt aaagaaaaga caggcaagac
    11281 atatgatatt aaaagtgtaa ttgaaataga gactgaagaa aaagaaaaga aaattgcctt
    11341 aaaagaaaaa gagaagagac ataaagagtt gataatagaa aaaatagata atgcaatgaa
    11401 aatattaagt gaagaagaaa aaaagatagt acagtataaa tacttttcaa gtagcaggac
    11461 atcttgggaa tatgttggca gaatgattgg tttttcagcg agtaagtgta agcaaatgag
    11521 gtttgatatt atagataaga taaaaggatt gctataaaaa tgtccgattt gtgacgattt
    11581 taaaccgatt tatgtctgtt ttgtgtctaa aaaatgtccg gtttgtgacc aatttatgtc
    11641 tgttttgtgt cttttaatca tgataagatt gtattgtgag aaaaatatat ttaataaaaa
    11701 tggcttggaa tttacgttct aagtcttttt tattgtctag agaggtgttg aagattaaac
    11761 gtgatataac agaagaaatt tcaagtgctg catatgtacc agacaatcta aagtattacg
    11821 acaatgtaat gaaagaaact cctggtatgt atggaagaga atgttcttta gattttataa
    11881 agaaaaagca agaaaaactc ttgaaactaa aaaagaaggt taagaaaaat tatgattcta
    11941 atattaataa gatagactca tatctaaaaa ttttagagaa aagtataatt gatgagtctg
    12001 atcacgttga gttggttgta tttaaattat atttgcaatt agaaaatgtt gtaaaagtaa
    12061 ctgaaactgt aaacgactta ggatttagaa taaagactaa cacttatgca agagaaagaa
    12121 aatatagtac aaatgatata acctctataa tcacagatcc ttttactgat gtagttgagg
    12181 acttaaaaat attagttcaa gagaggcaaa gaaaaaatta ttatggaaat aaggagtgtt
    12241 tttaatgaat ggaagcacat agtggacaaa aggttaatcc cataaaagat atagaggatg
    12301 tatttagact tttaaatttt ctagaagaat ggaatgaaag aaactattta ttagccctct
    12361 ttggaatgtg tactggactt agggtagggg atatattagc acttaaagtt gcagatgtaa
    12421 cagacttaaa actcgataaa aaaggaaata aaataagagt atctaaggat tggattagag
    12481 ttatcgaaga aaaaagagac tataatagag aggttttttt atctgatgta ataaaaagtg
    12541 ctatagaaaa ttatactcaa gataaaccag gagaagaatt tttatttaaa agtggcaaga
    12601 ggaagaaatt taatagacct atccaaacaa gacaagcagg aagaataata aaaggagcag
    12661 caaaaaaggt aggaataaaa gaaaatgttg caacacactc tttaagaaaa acatttgcaa
    12721 ggcatattta tgatgaagaa gagaataaga cttatgcatt agaacttata aggaagattc
    12781 taggacataa gacaatagaa atgactagaa gatatatagg aatagataag gatgaagaag
    12841 taaaagcaat aactaaattt actaataagt taaagaaaag aaaaagaaat taaaatatct
    12901 tgtattttat ctaaaattta atatgttacg tttttcaaca acaggacatt attagaatgc
    12961 aaagagcctt aacaatagag tttacaagga atagaataga tttattaaaa tgtctgaaaa
    13021 tatatattaa aggtcattta ttcaagggat ttatagggat gtagatattt aaatgtttat
    13081 ttagaagctg agtaaagagg tgattaattg gatgtgaatg aagttgaaat aatcgatagt
    13141 agctatgaaa aaggtaaaga gttgacagaa gatcagtgca atatggtaac tctattgatt
    13201 acaggtgcta cagtaacaga aactgccaga attattggag taaatagaaa aacaatctat
    13261 aattggatga ataaagagca tgttaggaaa gaaatggaca gacggaaaca ggagctaaca
    13321 aaccaaggaa atttaatgat attaaaggat ttagatagtt atatcaacaa tatcaaggaa
    13381 ttagctagtg acaagagcga taagagggtt atgttggcag ccaatcagta tcttataaat
    13441 cgtatatatg gaactcctac aagtacagtt atacaagcag aggataatag tgttggcatg
    13501 ggtatggatg caacagagat agaagcagct atagctaaga taagaataag aacaagcaag
    13561 aagtaattag atatgaaata aatcctgcaa gaatatgttt taattatgtt tgaaatcaat
    13621 taaagcaaaa catatattat atatatattt actttaataa ttaaatcata tattgtattt
    13681 aactttagtt atagctaatt taataaaatt tagtgagact taataattaa agtttcatac
    13741 agtgaagtga tgtggattat tataggatat gtgaacctat tggaaatgct aggttctttt
    13801 taactatgcc gaaaatacat atttaaggaa tagttgaaag ataattaata attctaatca
    13861 aaaaaatatt tcttgcaaga aaataattca aaatacttta atatatttat tttttttatt
    13921 aatagggggt gtccttctat tttgaaaaaa ttatttttta tggaaaatga gttctagaaa
    13981 ttttctagca aaatttaaaa accagagatg tatttcaaag agggtgattt tattagagaa
    14041 aaatttacat tgtttatttt attaattgca ttactcactg agcctaaaaa aatagaagaa
    14101 gtaagaggaa gtaaatacga gtggataatc tagaaagaaa tatacaatta atatttagtt
    14161 atctagcaaa gacttttata agaaatggag catctataaa agatgctgaa aaagaagcaa
    14221 atgagattat aaaagccaat tcaaacaatc tttggggagt taatggtctc gcttatcaac
    14281 ttggaaaaat aaacctagaa tttttctgta tgtattttat gcaagacaca tatttaccaa
    14341 aagaagataa tgctgctgct cctatagcta aagttcatca tgagctatgg gaagatatac
    14401 aagaatctat aattggagat ggttcacagc aattaggaag aatttatcca agagggacag
    14461 gtaaaagtgc atttggagat ttagcgacaa ctgtatggtc gcattgctat aaacataaga
    14521 catatacttt gatttgctct gacataggat ctacagcaga gaaatttgta aaagatataa
    14581 aaaatgcatt acttgaaaat gagtatatta aaaaagcatt tggtgtcctt ttaaatgata
    14641 atgatagaaa atacatttgt aatagtactc aactagagct aacaaataaa acttttattg
    14701 aagctatatc atcttcatca cccatgagag gaagaaaata caataataac cgtccagatc
    14761 ttatcatact tgatgattat cagtcagaag aaaatgttag aacagaagat gctagagaga
    14821 aaaaatttaa aagattttct gatgatgtaa aatatgctgc tcaaaaacca gtcataagaa
    14881 atggtaaaac tataaaaaga ggaacaactt ttatagcatt aggaacctta caacacaaag
    14941 aatgttttta tagtagacta aaaaatttac caacttggaa gtttaaatgc gaaaaaggag
    15001 ttttagttga taatgtagat gaattattta attctggttt atggcttaag ttcaaagaga
    15061 tcttatttga ttttaaaaat acaaatcatc ttgaagatgc taaagaattt tactgggaaa
    15121 atgaaaaaga aatgaaattc cctatattat ggccaagttt ttgggattgt ttagatatgg
    15181 ctctaagtta ttatgaaaat ccaacatctt ttaagcagga agtgcaaaat gatgtcaatt
    15241 ctataggaga aaaatggttt aaaactgtta gaacagaaac tagagaagaa attgaatcgc
    15301 atacttttaa aaagacaatg ctgttatgtg atccagcatc tgcgggtggg tcgaaacatg
    15361 actatagcgc ttttcttgtt ggaagtgaat cagaaaatgg tttactatat ggaagattgg
    15421 cagaactagc taaaataaat gctagaactg attttgataa atatatagac catatgattt
    15481 atttattaaa agtgtattca gatataacac atatttatat agaaaaaaat acatttaatg
    15541 gcgcagatgc caaccaatta gagtttaaaa taaaaaatga taatgttctt agttatagag
    15601 atatagaaat cattaatgag caacaaaaga aaaataaaga tgataaaatc tctactttaa
    15661 tacctgtttt aagcaaaggc caaatgattt ttgcagaaga agataaggaa tttatacagc
    15721 aaatacttga ttttacagga caaaaatact ctctacatga tgatgctccg gatatatcat
    15781 cggaatttat taatcgaatt aacaacataa aagtttctga gacagtaaat atctttgata
    15841 gaaaattatt aggtttttag ttgggaggta atttattggc taatagatca aagtttgaag
    15901 aagttcaaaa aactttaact aaaaaaggaa agaagttcaa tgttggaata ggaaaagatg
    15961 aaaaaggata ttttgcatat actcatagag caaggagtaa aagttatatt tcaaagcaag
    16021 atattccaat aaaagtttta aaatttatag agtctacagg ataggatgtg ttgttaatgg
    16081 aattagattt agacttaata aaagacatat atgacgattg gaactctaat aaatccgaat
    16141 atgatactat gtataagtat tataaaggtg aaacggatgc tattagcaac tataaaatgg
    16201 ttaccaagag atctaataat aagataaaca ctaatttctt aaaaaagttt attaatgaag
    16261 aagtcgctta ttctcttgca aataagatta cctatacaag tagatctggt gatgagaaga
    16321 ttataaatga tttagaatac tatacttgcc attggagtaa aaaacatgac tcagatttat
    16381 tgaggtatgc actattattt gggctttgct atgaacttta ctatgtaaaa gatgatgaaa
    16441 tacaagtaaa gataatcaag ccaacagatg gctgtcatta tgaaaatgaa aatggagaaa
    16501 tagtatgctt tattagagag tttaccaaag gtttcgaaga tgacacgtat gtagatgtat
    16561 atgacaaaga atatatatat cattttgatt caaatttcaa agaagttgaa agtcctacag
    16621 taaacaatat atttgatgga aatgttccaa tatcaatttg caaaagaagt gaagaactag
    16681 gaaaaaatac aatatttaat gatataaaag ggttacaaga tgcttatgaa actaatttaa
    16741 gtgatataag taatgaaatt agtgatttta gaaatgctta tttaaccttt tctggatgta
    16801 atattaaaga agatgatttg ccaaggatga aagaacttgg aatacttcaa gttaatggag
    16861 atggaaaaat agagtggctt attaaagata tgaatgatac atttgttcaa aatacactat
    16921 cttcaataaa agaaaatatg tatgaaatta catctcatat aaatcacaat gaaaaaatgc
    16981 aaagtaatac atcaagtcta gcagttatag caagattaat cagtacagaa tggatttgta
    17041 gccaaaataa tgatagtatt gcagatactt tatttaatag gtacaaatta ttgtgcattt
    17101 ggcttaataa aaaatatggt tttgactatg attataaaga tattaaggct aaatttaccc
    17161 ctaagatacc acgtgatgat ttagttgtag caaatatatt aagccaactt ggagataaat
    17221 tatctactga aactggctta tctcaactaa gtttcattga taatcctcat gctgaaatag
    17281 aaaaagctaa aaaagaacag gaaatagttt cagagggaga gattttatta gatgaatcaa
    17341 aagattataa ctaaattgac tgaagatata tataaatctg ctgaaaatag gacaaaacca
    17401 ttttataagt atcaaagaga aaatagggat aaacttttat tagaaatagc aaagatattg
    17461 ctaacacacg atattattaa tgaatactta aatattaata ataaagataa gaaaaatcta
    17521 aggtcaaaac ttaataaaat tataaatgag tattctaata gttatgatga agaagtcaag
    17581 gatatagaaa ctattttatc tgattcatct aagaataaat attcaaattt gataatttta
    17641 ttaggagtaa tactgaagat aaaagatgtt agtaatataa acaataaagt tataaataag
    17701 atagtgaata ataaggttga tggaaaacat tggagcgata gactctggaa gaataaaaaa
    17761 ggtatagaag agtccttaaa aaaagaaata aagagttttc taaatggaaa aacttctgta
    17821 aataagatag aaaaagcaat aagagataaa tattcaacag gtgcaggaca aaccagcaga
    17881 ctaatagaaa atgaagttgc cagatgtcaa agtgaagtaa atgagtattt tttcaaggtt
    17941 caagggatta taaaagtaat gtattgtgca gatttagatt ctcgcacatg tagtgattgt
    18001 tctatgcata atggagtgat attttatgtc aatgaagata ggccctcttt gccaagacac
    18061 tgtcactgta gatgtcaata tatacctgtt taacatgtat taattaattt aataggtgtt
    18121 tttattatgt ctaaaaaata tgaggtgaaa tatgaaagtt gaaatattag gaacagaata
    18181 tctagtgata gagaaacttg aaagcgaaga tgtgctatta aaggaaagag ctggatattg
    18241 tgatcactct gttaaggaaa ttgttataga gaaaataaat tctgaagaag gttcattgaa
    18301 agatttaagt gtatataaaa atgaagttgc taggcatgaa ataattcatg catttcttag
    18361 tgaaagtgga ttgaagagtt gtagttcttg ggctacaaac gaagaaatga ttgacttctt
    18421 tgcaattcaa tttcctaaaa tagtaaaggt tatggataaa atagaatgtt tgaattaaat
    18481 tttcaaaaag gagaacttta tacatgttaa aaaaagaagt gttggaatta ctaaaagaaa
    18541 tagaagatga tgcagaaata gattcattgc tgcaatcaac agatttattc aaatctgcat
    18601 ctgataaaaa gcttacaata gaagagttta gagaattaat taataatgat gcaaacttta
    18661 aagctattat agataatgaa aaaaataaat atcacagcga agcacttgaa aactttaaga
    18721 aaaaagatat gcagacactt ataagtgctg aagttctaaa aagaactgga gcaaatgaaa
    18781 cagaagagca aaaagcaata agggaattaa gagaaagcct agacaaacta aaaaaagaaa
    18841 agcagtacgc agaaaaagtt tctaaatata aagatatttt agttgaaaag aaaataccta
    18901 caaacttaat tgaatatcta ttatctgatg atgatgataa aacaaatgca aatatagaga
    18961 tatttgaaaa ttcaatgaag caatatgtgc agtcaaaggt agatgaaaga attaaagatg
    19021 gttcatacgt tccacctggc aaagatagtg caggttcgct atcagaaatt agaaaacaaa
    19081 taaagcaagg gctaaatagt ctttagtata aaaaaagaaa ggatgatttt ataaatggct
    19141 aatgtattac aatatgtaac actttttcaa caagaactag atatgcaggt aacagttggc
    19201 tcaactactg gatggatgga gaaaaatgct ggtcaagtta tatataatgg aggaagagag
    19261 gtaaaagtac caaaagtaac aatggatggc ttaggtgatt atgacagatc taaaggatat
    19321 acgcaaggcg cagttacact tgagtacgaa acaatgaaaa tggagatgga tagaggtagg
    19381 acttttatgt tagattcaat ggatgtaaat gaaagtaact tcgttataaa tgcatcttct
    19441 gtaatgggat tatttcaaaa gcaacatgtt ataccagaaa tagatgcata tagatactca
    19501 aagatatttt ctgaaacagc taaagtagat gagcgtgtaa aatattcata cgaagctaca
    19561 gtaactacaa tattaagtga attgaaaaat caacttgcat caatacaaga tttatctgga
    19621 gatatacctc ttattattag tatgtctagc ataattgcaa gcatattaga acaatcatct
    19681 caacttgatg atattgaatt tggcgatgga gatataaaaa gaattgtaaa gtctatagac
    19741 aatgtaccta taataaaagt tccatcaaaa agaatgaaaa cagaatacgt atttagagat
    19801 ggtaaaacat ctggacaaac agagggtggg tttactgaag gagcaaaggc tttagatata
    19861 aactggttaa taactccagc atctgctcca attgcagtat ctaagactga taagccaaga
    19921 atatttactc cagatcaaaa ccaaacagca gatgcttatc aaatagacta tagaaaatat
    19981 cacgatttgt ggatattgga tgaatattta aaactttgta gagcatctgt gagacaagct
    20041 aaagctgcac aagaataagg agttgtttta aatgtttgca ttgataaaaa ataacataat
    20101 taaagttgtt gaagatgaaa attcgagaga taaattgatt tcaaaaggat ttaaaatata
    20161 ttcagaagaa gtgactaaag agaatattga gaaaaaagaa gaaaaagtta aatcaacctc
    20221 taatgattta tttaatctat ctaaaccaga gcttatggaa attgctaaag gcaagaatat
    20281 aaagggatat tcaactaaaa ctaaagagga attaattcaa ctactagatg agtacaatgc
    20341 ttgataatgt taaattagtt ttaggaatag aaaatgatag atatgacaaa ttaataatcc
    20401 tttatataaa taaaataagt gagatggttt tagaatattg ttctaggcag gaactaagta
    20461 cagcactaga agggtttgta gaagaaaaag taatatcaat attatcttca agatttgaag
    20521 aacttaagaa aaatagtgga cttgataatc tagaaaaaag cttaaaagct ataactagag
    20581 gtgacactaa gatagaatat aatgctttaa cattacaaac tgctgaaaat agcatcagtt
    20641 catcatcttt tttaactgat actgataaaa aatttctaag cccattttgt attgttagta
    20701 tgtactaagg ggtgattaaa tgactgaagc agatatatta gaaatgacat accttgataa
    20761 aatgactata attagaaaat taaaaggctg gaatgaagaa acatgttcta atgattttag
    20821 taatgttgtt atagctgaaa atatcccatg tgcaatttct agaaaagaag aagccattgt
    20881 aaatggtgat attggatcta tagttgtaaa tagaaagtta ttttgtagac cagaagtaga
    20941 tataaaaata ggtgatacta taaatacaac ctataatcat ggagaagaag ctgtatttaa
    21001 ggtttctaag gcaaatatat atccaagcca tatggaaata cctattacag aattggagag
    21061 gatataatgg gaatagataa tttaggagtc tttgaagcat tagccttaga tttaggtcta
    21121 aatgcatcaa actttaatag aaaaatcaag aagtttacaa aagaaactgg gcaagaacta
    21181 gcagaaaata taagagatga aactcctgta aaaactgaaa agttaaaaaa gggatgggaa
    21241 gaaaagcaac cagaatatga tacttatatt gttaaaaatg aagttgatta tgctacttta
    21301 gtaaataatg gccattcaac taaaaatggt ggcattgtcc ctggttcttt tatggttgaa
    21361 aagggaattg aaagaacaaa agaaaatatg acaagtgcaa aagcaaattt atttgattgg
    21421 taggtgatta gttgcttaca aacagagaca ttataatagc agttaataaa agaatcgaaa
    21481 atgagtttag atatatagat atttttatta atgaggataa tatacaaggc tttgaggagg
    21541 cttgtttttt tgtgcaactt ttacctgttt ctaataatat tgcaaataaa gttttagata
    21601 ctaaaaagat attcatagat attgaatatt accaaaaggc tagaaaaaat aaattaaatc
    21661 tatacgacat acaaagtaga ttagaaaaaa tatttaacag aaacattaga gttaaagata
    21721 gaagtttaat cattgagaat atatctccat caatcgcaaa agatcctgta ggatataaac
    21781 taacttttct aatgactgta tcttattttg aagaagtcta ttttgaaaat gaaacatttg
    21841 aaattatgga aagtgtagat ttagagatag gaagtgatta aatgggttta ccagaaatta
    21901 atatttcttt tatccaagca ggaaaaactt ttgttaaacg ctctggtggt attgtagcgc
    21961 ttattttaaa agatacaaaa aatatagggt tagttgagat aaaagaaata gaggatattc
    22021 cagaaaatta ttctgctgct aatttagatt atataaaaat ggctatgaag ggaaatgtat
    22081 atcctccaaa taaagtatta gtttatacat tagatacaga tgaatcaata gatgatgcac
    22141 tagattttct tgaaacttgt gagtttaatt atctttgtat gccagatgag acagaacaag
    22201 atttgcctaa aatcaaaacg tggattaaga aaatgagaga agataataaa ataaaggtta
    22261 aagctattac tgcaagtaat tcagcggatt atgaaggtat aataaacttt acagcaactg
    22321 atattgaagt tgaaggtaaa aaatacactt caaatgaatt tctgccaaga atagcaggtt
    22381 ttattgcagg aactccatca actcaatctg taacatatgc agaaatacca gaagttacta
    22441 atatacctaa gctaacaaga gctgaagcaa atacaaggat aaataatgga gagctaattt
    22501 taataaaaga aagtggagct atagtaatcg ctagaggagt tacatccttt acaacaatta
    22561 ctgattcaaa aggtgatata ttcaaaaaga ttaagttggt tgatacacta gatcaaattc
    22621 ataacgatat taaaaaaata attgtaaaaa attatatagg aaaaacccaa aacacttatg
    22681 ataataagtg tttacttatt gttgcaatac aattatatct tcaagaatta gaaaaagatg
    22741 gtttaattga tgaaggttca actgtagaaa ttaatttaga tgctcaaaga gcatggctaa
    22801 aaaaacaaaa tatagatata tctaatatgg aagaacaaca gataaaagaa tacaatactg
    22861 acactcttgt atttttaaaa gcaagaatta aattaataga tgcaatggaa gatgtatatt
    22921 tagacatctc tatgtagttt ggaggttaaa atttgaaagc taaaatagat gcaaaaagaa
    22981 taatatctgg tacttttgga gagtgttggc tagataataa gcaacttaca tcaacaaaag
    23041 ggatggaggc caaggttgat atagataaag aagaaataaa attatgtggt caaataatga
    23101 ccacatataa aatgattggt gcaactggaa aaggatctat aactctttat aagataagta
    23161 ccttatttgg cgagtatgtc gaaaaaatgt taaatgaagg taaagaattt aaagtaacta
    23221 taataagtaa attgcaagac ccagattcat atggttctga gagaattgca ctttatggat
    23281 gtatgtttga cgacttaact ttggctgatt gggaagctgc gaaagttgga gaaatagaag
    23341 ttccattcac atttgaaggc tttgaatact tagataaaat aaaagaaaaa taggaggatt
    23401 ttattatatg aacacagtag aaaaattatt aaatatggat gcaggtaaat taaaaatgcc
    23461 atctagcgca tttgaattat attgtaaaaa actagatgat actttagaaa tagagtgcaa
    23521 ggctattgat ccagaacgtt ttgacgaaat aagaatgaac tctatggacg ttaatagtgg
    23581 agatgtagaa aacattaaca tatatgaact taaagtaaat acaatattag aatcatgttc
    23641 tatatttagc aatatggaat tagttaaaaa atttagtgca attacaccta aagaattaat
    23701 taaaaagcta ttacttagtg gtgaaataga taaattatac gaggaggtta ataaagtaaa
    23761 tggaatagat gcagagggag ataaaaaaag acaaaaagaa agagctaaag atataaaaaa
    23821 ctaattaaaa cggatggaga agttaacttg atgtacttat tatttaagta taaaggtata
    23881 atgccatccg tttcttatca tatactaaga ggcgaaaaag aaattgttag tgtttttatg
    23941 gatcaagaat tagatgaaag aaaagaagaa ataaaatctg gtgttgggag gttgttttag
    24001 tatatgagtt ctaatacaaa ggtcctacaa gcaataataa aaatgagaga tgaagcaagt
    24061 tcaacattaa aaagagtagc agcaaatact agagctctac atgattcatc ttcccaagca
    24121 tcaagagcat taaataatgt tcaaagtaat ttaaaaagtg ttggaactag tgctttaaaa
    24181 gcaggaggtc ttatcactgc tggagttggt ggtgcatttg cagctgcaac taaagttgga
    24241 acagaatttg aaagcgctat gtcgcaagtt aaggctacat ttggaaattc cttaaaacca
    24301 ggagattttg aagctctgtc taaggctgct agagatgctg gaaaagctac aactaaaact
    24361 gctgctgatt ctgctaatgc acttcagtat atggggcttg ctggatggga tgttcaaaag
    24421 tcaatgcatg ccttaatgcc agtgcttaat ttatcagaag cagcctctat ggatcttggt
    24481 ctagcatcag atttagtaac tgatagcatg agttccatgt gcttagaagt tgataaggtc
    24541 agtaaaagtg gaaaagtact agctggtgca ggtttaagtg agtatttaga taaagttgca
    24601 aatgcatcta ctaaatcaaa tacaagtata caacagttga tggaagcgtt taatgtcgca
    24661 ggtggtacat ttagcaattt aaaagttcca ctttcagaag caactgctat catgggaata
    24721 cttgcaaata gaggagttaa gggtacagat gcagggcatg ctttaaactc tatcatggta
    24781 aatcttacaa caggtgcagg tcaagcaggt aaggcaatga aaaagttagg tgtaagtgca
    24841 tttgataatc aaggtaaatt taaaggtatg tcaaatgtgc ttaaagaggt tgcaaataaa
    24901 actaaaggta tgactgatga acagaaaaat tattacttat ctgctattgg tggaaagact
    24961 caattaaaaa cgttacaaaa gttacttgat ggtgtgggaa atgaatatga tagcttaaag
    25021 aaaaaaatag ataattcaaa aggtgcttta aaaacaatgt ctgatgtaat gaaggataat
    25081 actaagggtg gacttgcaac cttaaaatca gcccttgaag aaactggaat tactatttac
    25141 tatcaactaa agccagcaat agcatctgta gttgataatt taactaaaat gactgtttgg
    25201 tttaataatc taagtgaacc aataaaaaga gtcataacta atgtaatgct ttcagttgga
    25261 gcatttggag tacttttatt aactataggg gctgtgtctt taattgtttc aaaagctata
    25321 ggtatatttg gcttttttgt tccaataata ttaagagcaa aagttgcttt cagagctttt
    25381 gtaattggta tgaaaccatt aagtgcagta tttttagctg taatgggtcc tgtgggatgg
    25441 actataacag ctgtaattgc attatcagta gcatttacca ttgcttatgc taaatctgaa
    25501 gtatttagaa ataaggttaa ttcattagta aaatcattta cagaatttgc aaagcctata
    25561 gtaaattttt gtatgcctgc acttaaacag ctaggagaga aatttaaaga gttgttatca
    25621 gcatttggtc cactatttgc atctatttta aacctaggaa gtgtaataat gaaggtacta
    25681 ggacctgttt taatcggcgt aataggtttt catatagcaa aattagtttt gattttatct
    25741 actctggcaa ctgcttttaa agctgtagtt gatactataa ctaatgtatt aaatggtcta
    25801 gcatctattt taaatggagt atttgattta attataggta ttgtcacagg cgatagtaaa
    25861 aagatgatgg atggagttaa acaaatattt gatggtggaa ctaaaattat aaaatcaatt
    25921 tggaaaggtt tcatagattt tgtaactgct cctatacaag ctatagctga tatagctgac
    25981 agcttattta aagataaagc taaatggctt acagataagt ggagagattt aagaacattc
    26041 ttagaaaatc caattgaagc aactgccaaa atatctacta aaacaaatgt aaatatccca
    26101 ggaagtaaag cagcagatgc agctggtaaa tctacaccaa atacaggtgg attaaaacaa
    26161 acagtagcaa atctaaaagg ttcatttagt gattttaaaa cttttattaa gcctatgaca
    26221 gactctataa gtcaaggagt tgaatctgga aaaactaaat ttacagaact gcaaaataaa
    26281 atattaaatg atgttaaacc tgcactaaag gtcctagagg attctggagt aaattttaag
    26341 gataagttta aggagtcaat aacttcaata aaagataaat ttaatgaatt aaagaacata
    26401 ttagctggaa atattaaaac aaatatagat aatttagtaa aagcatttga acctttaaaa
    26461 cctcatttag ataatttgaa agattgcttt gataaggtta aaaaagcgat tactgatttt
    26521 tttactccag ccaaacaggt tggagataca gtaaacaaag taagccaacc aatggatagt
    26581 gttaaaaagt ctactgatgg aattaaactt tctttccaaa gtttaactca agcacttgct
    26641 cctgttaaag cttggtttca aggatttatg cctttcctat cacaaatagg acaacaactt
    26701 ttaccatcta taggaattgc aatagctggt gttgttggcg gaataatttt agcatttaca
    26761 tgggttttaa atacattgac cgcaataata acaacagtat ctggaatcat aaatggaatt
    26821 atgtctttta tatctggaat tattaatgtt attatggggc ttataacagg aaatgctgat
    26881 caaactatgg atggacttaa acaaatattt gatagtggag taggtgtaat aaaatcaatt
    26941 tggaatggcc ttgttgatct agttagtggc gtactagaac ctgtaataga tcttgctgat
    27001 tctcttttca aagataaagt taaaggggta aaagaagctt ggaataaact taaagatttc
    27061 tttaaacatc caattaaggg aacaatagaa atatttaaaa aaggtcctag tttacaaatt
    27121 ggaaaaggtg cagatgctgc tggcaaaagt ccaagaaaag catttggtat aaatagagtt
    27181 cctagaaatg attatttaat aagagcacac gaaggcgaga aacttttaac caaacaagaa
    27241 gctaatcaat acaaaaggaa tagttcaaat ggaagtttat ttcttgataa attggctgat
    27301 acaataattg taagagaaga ggctgacata gataaaattg taagaaaaat aaacaaaaaa
    27361 atatctcttg caaaaattgg aggtgttttg taaattatcg tgctataatt gtagtatata
    27421 atttacaggg ggttatgtta tgaataaaaa aatactagta ttaacaatat caattatact
    27481 atctttaagt ttagttggat gcagcacaaa taattcaaaa aatagagata gtaaatctaa
    27541 gcaaaacaca gaggaagtta aaaatcataa aataggcgaa gttgttgatt tagatggagc
    27601 aaaagtatct gttaaaaata ttaggaaatt agaaacaaat agtaatgatt atgctgttga
    27661 aattgaaata actaatacag gtgataatga tttacaaagt gattatctag aaaactatat
    27721 attaaaatca agtgacaata ctactggaga agcaataaat aaccaagaat taaatggaga
    27781 gttaatgttt gatacaatac gcccaggaga tactttgaaa ggtgaaatag cattcgaact
    27841 tacaaaagat gcaacaccaa aaacacttga aattgcttat gaaaatgtag gcaaatatac
    27901 agtatttgat ttatagtaat tatcttaaaa gacgcttatt tacttaagtg tcttttattt
    27961 taggaggagt ttaatggaaa tatggttaag acaagcaaat aatacattta ggtttcctgt
    28021 tattccaccc tcttttgaga taaatggaag tgcgacaata aatacatcta atattttaag
    28081 tgttggagat atcgcagtat ttggaggatt agggcttaaa actatagaac tatcctcttt
    28141 tttccctaat caagaatata gtttctgtaa ttataatgga tttccaaaac catatgattg
    28201 tgtaaattta atagaaagtt ggatgaaaga aggatatata ttaagattta tcattacgga
    28261 aactaatata aactttgaat gtataattgc agattttaat tatagagaac aagattattc
    28321 aagagatatt tattttacct taagtctaaa agaatacaga aggatacaaa tatccaaagt
    28381 aaacattaat aatgatgaaa aattatcttc tgaaaagaat gttcctctaa caaaaggatt
    28441 tgatactaag caaaaaacgc ataaggttgt tgaaggagat actcttttta agatagctaa
    28501 aaaatattat agcaatggag atttatggga gaagatttat aaagcaaatg aagatgagat
    28561 taaagatcca tctgtaataa aaaatggttg ggtattaata attccttaaa aatggtggtg
    28621 atttataatt aataaaatca aaatacaagt tcatataaaa aacggaaata tatataatgt
    28681 aactgattta gtggataaat gcacttggtc tggtgattat agatcaccat caagaacttt
    28741 ggaattttct ataattcaat ctgcaagtga tattaatttt aggcagatag atattccagt
    28801 agcaagtaca gtttgtttct atgtagatga taaagaactt tttagaggaa tgataataga
    28861 tagatctaaa gactctagca ataataatat agattttaca gctaaagata tgggtttttt
    28921 acttttacaa agcgaagtgt catacaattt taaagataaa ttagtcgaag atattgcaaa
    28981 acaggttttt gtagataata aattcccact aggtaattta cctaaaacta acgttaaata
    29041 tacaaaaatg tttattggtg taactggcta cgatactata atgagcgttt atacagaagc
    29101 aagcaagaca actaaaaaaa agtatatgat agagtctaat cttgataaat ttaatgttat
    29161 tgagaagggt gtagttactt taaatataac atttgaagaa ggctttaatc ttatcaatac
    29221 aaatttttct gaaagcattg agaatgtaaa aaataaagta ctagttgttg atcagtatgg
    29281 taataaaatt agtgagaaaa taaatgactc tatatttaaa gacgttgggg taattatgca
    29341 aaaggtaata caacaacaag aaaacagtac tatagacata gatggagagt ttaaaggaat
    29401 cgaaaaaact tgctctttaa aaggatatgg tgatataact tgtgtaactg gtagaggtgt
    29461 aaaagtaaaa gactcatata caaaattaat aggtcttttt tatatagata cagataagca
    29521 tacatggcaa aatggagatt atcaaattga actagagctt aattttgaga atataatgga
    29581 tgaaaaatct gctggccaag atgagcaaaa agaagatggt tcagagtata ctggaggaac
    29641 agaataccct gctgaattta cggcttattg tcctagaaaa gaagagggtg gaaatacaga
    29701 ttgtagaggt aaaaaactag atccttctaa aaagacatgt gccgctccta tggttggagc
    29761 atatgaaaaa tcttactata caaaagattt cttaaacaaa catcctctta tgagatatgg
    29821 agatgaaata caattagtta caggtgtttc aagccgagat ggaacgtata aagtaaatga
    29881 taatgggcct gcaataatta tagaaaagga tggaacatat catatagata ttttatttgg
    29941 aaatgttgaa gaagctaata actttggaag aagaaaagga aagattataa ttggtggtta
    30001 ttctggaaac atgacagaaa aagcaaaaac agtaatttca gaagcaagaa aacatcttgg
    30061 aaagccatac aaatggggtg ggaatggacc aagtagcttt gattgttctg gactaatggt
    30121 atattgcttt aagaaggtta atgttaattt accaagaacc tcaagtcagc aatctaaggt
    30181 aggtaagaaa gtagagaaaa ataatttaca ggcaggagat ttggtatttt tccataatcc
    30241 agtcagccat gttggactat atgtaggtaa tggagaattt ttacatgcgc cacaaacagg
    30301 agatgtagtt aaaataagta aattaagtaa tagaaaagat tttaatacag ctagaagagt
    30361 tttgtaaaag aggtgatatc gtggcagatc caatcaatga atttatagga ataattaggc
    30421 aagaaggtaa atttcataat gaaccttctt tttttattgg aaaaattaaa agtaaattac
    30481 cagatttaaa aatagagata aataacatca tattagaaaa agaagatatt ttgatagata
    30541 gttggatgct tgatagacag atagagttat ttgatacaga aacaagtcaa gaacataaac
    30601 atgaaataaa aaatcccttt atagatactt ttgaatctgg aaacacagta ataatgttta
    30661 aaataggtga aaaatttgct gttgtaagta aattggtgag tctagatgaa taatactata
    30721 ttccctttca tgggtgttcc agaagattat atttctccag acaatgaaga attacctatt
    30781 tttaaagaat ttgcttggga ttttaataaa gatgaaaaga taattgaaaa tggagacttt
    30841 aaaatagttg aaagaaatga agcaattaaa gtatggattt acaaaacaat aaaaacagat
    30901 aagtatgttc atttaatata tgattggagt tatggaacag atataaaaaa tctaataggg
    30961 caaaagtata ctaaaggtct tactgaaagt gaggcaaaaa ggtatataca agaagctcta
    31021 ttaactaatc catatatatt agaagtcaat ataacaaatg cagaatttga agatgataat
    31081 ttatctataa gtttaaatgt aaaaacaatt tatggagagg aggagattac ttttgtataa
    31141 tggccaatca ttcagtacct taaataatag aactttaaat aacataaatc tccctcttta
    31201 taaaggccaa ggatcttctc tttataatat agtttctcca ataaattcag aacttgcaca
    31261 attatatata gaactttctt atatacataa gagagttttt attcaagata attttgacga
    31321 ttttcttgat agaagagtca atgaatttgg cgtatataga aaattaggta cagaggcaat
    31381 aggtgaggta acatttgagg gcaaaattgg aactcaaata ccaaatggaa caataatatc
    31441 tcatagtgat ttactatttg taattattaa agatattaca atagatgaaa atagtaaatt
    31501 aaatgtaagc cctatacagg ctttagagat tggcattaag tataatttat cagctaacac
    31561 agaatttaaa cttatagaag aaataactgg agtaactaaa atttataatg aacttgacct
    31621 aaagggtgga acagaaatag aaactgatga agaattaaaa gaaaggttct ataaaataca
    31681 aaaaaatcaa gcgacaagtg gaaataaggc gcattaccaa tcttgggctt tagaggttga
    31741 aggtgtttat aatgcaaaag taattcctcg ttgggatggt ccaggtacaa ttaaaattct
    31801 aatttatggt caaaacaatc aatcagttga caatgaagta ttgcaaagat gtactgaaca
    31861 tatagaagaa gaaaaaccta ttggacctac tgttacaatt gttacaccaa gtacttttga
    31921 tattaatatt agtgcaactt taacacttga aaatggatat gatattgaat ctataaaagt
    31981 tgtgttttta gatattataa attcttattt gatagaaaat tcaagagaga ttgtttatat
    32041 aaaagtaatg agtttgttag caagcataga aggtattcat gatataaaaa atctccttgt
    32101 aaatggtgat gttaaaaaca taatagttga tgaagaaaaa gttcctgctg tttcaagtgc
    32161 tatatttgat atcgaggtga gttaaattga agttaattga ttacctgcca agttttgcaa
    32221 acaatgaaat tgacatacaa atccaagaag cacttgaaaa tgaactttta acgctaattg
    32281 atgaaaaaga tgatttatta gaacagtttt ttatagatac agcaacttgg ggacttgatg
    32341 attgggagaa ccttttaagc ataaaagtaa attataagtt agacttcgat actagaagaa
    32401 gcaatataaa agcaaagatg agaggtaagg gtacaacaac aatagaggtt ataaaagcta
    32461 tctcggaagc ttacacaaag accaatgttg atgtagaagt atttagtaat ctatttagtt
    32521 ttacacttag ttttataaca aataattgta gttataacac tattttagaa ttagataaga
    32581 aaatagaaga aataaaacct gcacaccttg aacacaaatt cgagaggata ttatttaata
    32641 aaaacgagct ttatacaggt gcagcaatta gtacaggaga aacagttaca atatatcctt
    32701 atgtacctag aaatttagaa agttttggag aaatagctat ttgtagtgga aatgatagag
    32761 cattagaaaa agtaacattg tatcctaaaa aatagaaatg aggtgataaa attgacagaa
    32821 caacaatatt ttactctagt aactgacatt ggtaaggcag caatagcaaa tgcaagtatt
    32881 acaggtgaaa aagtagattt tgcaaagata aaagttggag atggaggagg gagttcttat
    32941 actccaaatg agagtcagac agcactaaaa aatgtggttt gggaaagtac acttgaacat
    33001 gcacaaggag ataaagataa tcctaactgg gtagtaatac aaaaattcat acctggtgat
    33061 gttggaggat ttgaaataag agaagttggt ctatttgatt ctaaagacca attattagcg
    33121 atttctagtt acccaacaac atataaacct actgcggatt cagggactgt aaaagaacta
    33181 ttaataaaag taatattagt tgtatctaat gtagctaata ttaatttgaa agtagaccca
    33241 accgtaattt tagcaacttt aaaagatata caagaattag acactaaaat agatacaact
    33301 aaaacagaat taacaagcaa catagaaact gctaaaacag agttgaacac taaaatagga
    33361 gatacaacac aacttactac aacagataaa acaaatatcg ttagtgcatt aaatgaggta
    33421 aaaactagtg tagatagtat agaaacaaca gcagataaaa caagtataaa agatacagat
    33481 aatttatttg agagcgacaa cgtagaggga gcattaaaag aagtgatgca agaagtaaaa
    33541 ggtaatagaa gcagtattat atcaacaata aatagtaatt taataccaat gtagaaagtg
    33601 aggtgataaa gtgaagatat ggaaatacaa tagaactgtg aagaaaagaa gaggtgtcta
    33661 tacagaatta gatatacttg cacaaaggta tgaatttgaa gcagatggga aactttatac
    33721 agcttatttt catttatata ctaataagaa tatagatata ttcagagata aagatttata
    33781 taaagaatct tatatgatga gctatagagt tggaaatgta acaactgata ttgatgatgt
    33841 agtacagcaa acaactacag taagatttat acctgaccct gttattgata ttgtgattga
    33901 taacattagc agaggatgtg aaataaacta cagaattata gataatgaac caagtgtaaa
    33961 attcattgtt acagaaaagt taaatggcac aataatagaa acaaagacaa attctagtga
    34021 taataattat aaacttaaat taactgatga acaaatagta ccattagcat tcaattccca
    34081 aaattcaata gtaatagaaa taagtacaga agatggtgga ttagtaacaa gtaaaacagt
    34141 aacatttaca agaacaaata acaagccaac aattttagtt aattcatata gttctaattc
    34201 tgcaaaattt acagcatctg atttagataa taatttaagt aaaattgagt ggtatttaga
    34261 tgatgtatta aaagaaacaa taacaacaga tttaacagca gaaaaaacca tcaactatga
    34321 atttacagac aatgcaatac acacattaaa aatagttgct acagatgcag aaaatgcaac
    34381 agttgagaag gttttaagta taagtaaaga gataatgcca cttcaatctg atgctagttt
    34441 aagtgatata tcaactaagc tgatagagat tggagaaggg tttagaaatg gtaaaacaag
    34501 tattataaac actttagcac ttaaaaatat agaagcaagt ttaaataata cacttgtgga
    34561 gttatcagag aaaataaaaa caagttttga tagttcagac gctagtgtgc aggatttgca
    34621 aaatagaata acagaattga ataatcagct tagtcgaaga aaaaaatggg ctacaggtag
    34681 atacacattt actagagaag aagatactat caatttcaga atggttgatg gagatagtct
    34741 ttccgcagta aaaaaactaa ttatacccat taatttagat tttgttccaa gtgttattat
    34801 aatagacaaa atgtttttag gtagttacgt acctgcacaa gatgtgcaat ttaattgtgt
    34861 ttcaaactta gccgatttta cacttggacg tcgtttctat aataaacaat ggatttgcac
    34921 ttcttctata aaactagatt cagttacaca aaatagtttt actctttctt tacaaaaagt
    34981 tgttccattt gataaagtta gtagtacgat tttttctatt attaatactg gttttgcttg
    35041 gagagcatat gaataaaaat ataaattaga ggtgattaaa tgaatagaaa taatagaata
    35101 atttacgacc aaacaggcaa gatatggctt caaactggtg aagcaatagg agatatacaa
    35161 gagttgtcag aaataactga attaaatttc atagatgttg aatttggtag tatagactat
    35221 agtaaacaat atatagagtc tataaatcca gttacaaaag aattaaatat aaaaaatata
    35281 gaagttgttt tgactgatga acaaaagaga ttagaagtat tagaaaaaga actaaatatg
    35341 ttaaaagaag aaaataaaaa tagagattct gagatagtaa atacagcatt tgaagtagga
    35401 aatatcaaat taaacaataa tttataggag gaaattatat gtataactta ttaaagttaa
    35461 tgatagaaca aaaaaactat agcactaagg aggatttaca acataagatg gatgtattct
    35521 atgcagtaaa taggattaca gaagaacaat atttagagtt aacaggttta ttaaataaag
    35581 aagaaacacc agtagaacca acaatatagg ttctttttta ttgaaagaag gtgactaaat
    35641 gacttttaaa gaattagtta gtaaagttag aaatcttgta ttagaagcaa agaatgtaac
    35701 tatagaagat acagagaata aattcactag tgaaaatgtc gagggagcat tgaaagagtg
    35761 tatagataga gcagatttgg cttttcaaag tgccgatagt ggaaaagagt taattgcaac
    35821 tgctatcggc tctcctgcta catccgaaca aacatttcaa gagtatgcta attatattgc
    35881 aggatttaaa aatactataa gtcagttaaa ttctaaatat aaatatacta gtggaacttt
    35941 tacctattat actggtgcat atcctaatgg gctaaatata ggttttagac cagatattat
    36001 ttcctatact gccattaatg ctgtagagga aaaatattat tgtgtataca cacctttatt
    36061 ctatcttttt tataattata caactggaga aaaatatctt gatgttaatc ataatcgtta
    36121 tggaataact tttactgaca atggatggat acctagaaat ccagttaaca atggtgtgta
    36181 tagttatata gcagctaagt gccgttagtt gtcaaagact tagataaatt tctaagtctt
    36241 attttaatac aaaattagga ggaagtatga acgtaacaat agttttttta gcaacaaata
    36301 tatttataaa attagtaata ttagcaatag catttgatac attgctaggt tgtctaagag
    36361 caataaaaac acatcagttt aatagctctt ttggaataaa tggaggaata agaaaagttg
    36421 caatgatagc atgtatattt tttctagcag tagttgacat acttacaaag tttaactttt
    36481 tatttatgtt gccacaagat tgggttgatt tcttacgact aaatcatcta ggaatatctg
    36541 aatttttctc tattttattc attctatatg aaagtgtaag tatattaaaa aatatgtatt
    36601 tatgtggatt accagttcct aaacgattaa aagagaaaat aggtagttta ttagatacta
    36661 tgacagatga attaaatgtt aaaggaggaa aataaataat gaaaatatgt attacagtag
    36721 gacacagtat tttaaaaagt ggagcatgta cttctgctga tggagtagtt aacgagtatc
    36781 aatacaataa atctcttgca ccagtattag cagatatatt tagaaaagaa gggcataagg
    36841 tagatgtaat aatatgccca gaaaagcagt ttaaaactaa gagtgaggaa aagtcttata
    36901 aaatacctag agttaatgct ggaggatatg acttactcat agaactacat ttaaatgcaa
    36961 gtgataggca aggaaaaggc tcagaggttc tatattacag taataaaggt ctagagtatg
    37021 caactagaat atgtaagaaa ctaggtacag tatttaaaaa tagaggagct aaattagata
    37081 aaagtttata tattttaaac agttctaaac ccactgcaat actaattgaa agtttctttt
    37141 gtgataacaa ggaggattat gagaaggcta agaaacttgg atatgaaggt atggctaagt
    37201 taattgtaga aggtgtatta aataagagta ttgaaagtaa tgaggtgaag caaatgtata
    37261 aacacacaat agtgtacagt ggtgatgata gagtatcagc agatatttta ggattatatt
    37321 ataagagagc aaaagaaagt tatctagtta tagatataaa agactataaa ccacatagaa
    37381 cacaaaatct atatgtaatt ggtggagtaa cttgtaataa aatgaaagaa atgagtaaga
    37441 ctacaggaga aaaatttact caactatatg gtaatgatgt atggtcaaca atggataaag
    37501 ttatagaatt tgtaaaagaa aaattataaa ttaaaagaca acctttaaaa attaattgtt
    37561 aataaaacta ataaaatttt caactcagaa ggagcattat atgttaacat ttttagattt
    37621 gtttgctggc attggaggtt ttaggctagc aatggaaaga gcaggacaca aatgcgtagg
    37681 ccattgcgaa tacgataaat ttgcaaactt aagttacaaa gcaatgcata acccaaagga
    37741 ggatgaatgg tttgaaaaag acattagaga aattagagca gaaaatattc ccaaagcaga
    37801 tgtgtggtgt tttggattcc catgtcaaga cattagcatt gcagggaaca aacttggatt
    37861 caaaggaaat cgttcaagtt tatttttctc agttacaaaa cttattagag aacttaaaga
    37921 agaagataga cccaagtact tacttattga gaacgttaaa aatctactta gtgttaatag
    37981 aggatttgac ttcgccaaac ttctcattga gttggatgaa atcggctaca atgcagaatg
    38041 gcaaaatctc aattctaaaa acttcagagt tccccaaaac agagacagaa tatacattgt
    38101 tggacatctt agaagaagaa gtacaagaga agtatttcct atcacaggaa cgagtagaaa
    38161 aactactctt gagcaattaa ataatcctaa tcacagttca aacaggattt ataattcaaa
    38221 tggattatca aagtgtttat taagtaaagg tgggaacaat acaggtcttt atagagttgg
    38281 caatatcaat cctagtggaa atggtgcagg cggacaagtg tatagtagcg aaggcttttc
    38341 tcccacactt acaactggaa aaggtgaaag cccaaagata ttaattaaag agaatactaa
    38401 aaaaggatac atcaaagcat ctataggaga tgggataaga ctagatcata tagaaggtaa
    38461 aactggccgt ggaagagttc agcacaaaaa aagttgtact ttgactactg caagtaatgc
    38521 tggcgtaatt ggtaaaaaat ttagagtaag gaggttgact ccaaaagaat gttttaggtt
    38581 acaaggattt ccagacgatt attacgatag agcggcaagt gtctgttcag aaactcaact
    38641 atacaagcaa gcaggcaata gtgttactgt agatgttgtt gaagaaatag caaagaaatt
    38701 aaaatagaat attaatacaa tgcaaaatgt ggtaggtttt tccttccgca ttttgcattg
    38761 cattagcttt tttggaataa cttacctgta ctatcttaaa taaaaaaatg ctactatatt
    38821 ataaacattt acaaggagtg cataatgtta atacaaagct taaaacgtgg cgaattaatt
    38881 gtaatgaaaa tcttttagaa aagaaattca agaatatcaa agaaagaaat tattcgcatt
    38941 tgcaatgaaa aacacaattg gcggaaatct gcgacaaaaa ctctacttaa aagacttgtt
    39001 aaaaaaagag ttctacttaa gagaattaaa attttccaca tatattacat acctatagtt
    39061 acagaaaaag aatatttcaa atataaaata aatgatttag agccagatta tttagatgaa
    39121 tattttatac gattaatgtc cactgtacat aaatttaaaa atctagatga agaagattaa
    39181 atatctccct tcatctactc ttcacatatt ttaatagact ttcaagcaat aattgactta
    39241 acaaatcatg cttatcataa tgtttattct catctgcaaa tttattaaac atttcccaca
    39301 ctgtattatt tattctaact gtagttcttt ttatagattg atctggaaga tctatagata
    39361 tatcattttc tttaatgaca catatatgat aactatcatc tttagtttta aaccattcca
    39421 gcacattctt tatattatca atttcactag ataaatattt aatatcgtca tcaatcttac
    39481 tgctaatgct atctatatga tatttatcat cataactttt attatcttct acaaacttgt
    39541 ttccagttct tttatatcct ttcttattaa gccacttcct tatagtactt tcatttgccc
    39601 ctaattcatc tccaactttt ttaagacttt caaattcact taatttatta ttaatacaat
    39661 caacaacttc attaatattt ttttctttca aatcactcca agtcatataa atcctcctca
    39721 aaaaaataat agattacaaa tatcatatat ttgtaatcta ttatacatac tataaactaa
    39781 atcctttttt atttcatcat ttttttgtat ccttttgcat ttgcaaaaac atgtttatct
    39841 acatcactca taactattat gccaggtata ttctttttaa atgcttcacc taacaattta
    39901 gcgcctccac ccataacaac aaccgcagct gtactaactg gataatttaa tttcaattca
    39961 ttgtatattt ctttaaatag agaaatagat gcatctatat ttttctttat atcttgtttt
    40021 tcaccattta ggtaaaatcc tttatttatg tagtcttgta ttttttctct ttttatctca
    40081 actttaccta aaaatctttc gtccatctca agagatttct ttattgcatc atatatattt
    40141 attgttccca catttataga atatggatca gtcgctttat tcccttgtac aagcgcaata
    40201 tctgttgtct ttccaccaat atcaactaaa acaacatctc ttcctgcaat ttggtcaact
    40261 atgtcttttg cataatataa gtatcctgta acaccttctg gaaatgtttg aatagatctt
    40321 attgttatat ctcttttagt agtctcattt cctcttgtaa actcaacatg atattctttt
    40381 ccttgtaatt tttcaataag attttttctt aatccggcaa attgtttcac tggcagacct
    40441 agccctagat caacaatttc atcatctgta tttctacata tagcccctaa tagtagtggt
    40501 aagaagtttt ctttctcata tttaactata tttatttcct cgtcaccttc acctaggtaa
    40561 tatgttttat tgcctatttt aatgctatct gaatctgaac caaagttttt tacctctgta
    40621 actttacttt caaaaatatc atctgtactt gttttaactg cataatttcc aatatctata
    40681 cctaatttac tcatttatgt tatttccccc ttattattct aaacttccaa aatcaaaatt
    40741 gttagctgga tcttctattt cttttttctg ttcaactaca gcattatcct ttttttcttg
    40801 cattttttcc caaacaagct cttttaagta agctgtagct gataatttct catctaaaaa
    40861 cttttcaatt gctttttctt tatcattgtt tttaaatgtt agaactatcc tactcattca
    40921 accacttcct tttttataaa atattataaa atttattaat atttatatat attttactaa
    40981 attttacaca gtaattcaat agatttataa gatatttttt ataatatttt ataatttttt
    41041 acgtaatttt ataatttttt ataaaattta tcattttgta tataattaaa aacacacttt
    41101 ttataatttt gcataaaaaa agagtgtttc atatatttct aaacactctt ttctactttt
    41161 tataattatc taattgtaaa agaagcttca gctggactag agaataatat aatacctcct
    41221 gtacacacac cttttccttt aaatttagca atatatgaac ccttttttag ccctttaaaa
    41281 gttactacac cagttttagt agttccagct aatctaaagc ctacatactg agatgataca
    41341 attttgccag ccttatatac atctatattt ccttcaaatc ctaaaatatt tccaagcgta
    41401 gatgttactc tccaagataa ctgcccacca ctcattgcag ttaaattagc agtaccacct
    41461 ggaacaacaa cagatttagt cgaaggcgaa tctgagtttg gttggccaat taattcaact
    41521 gtttgtgaat ttccagtacc ttcataatca tttccatcag caaaagctgt aaatggaatc
    41581 attactgcgc aaagcgttag taataaagca attgtttttt tcatttgttt tccccctatt
    41641 tttttatatt attctcaatt acagtttcct ttctttacgt gccttaataa tcatattgta
    41701 attatgctca gcagtttcaa atgctcctac caaaggagtt ataattacac tttctattaa
    41761 gcacaattca tcatagttta aactagcttc tccagcatag aaattattta acttatctaa
    41821 atctattcta gttaaaacgg aaactgattc cattgagaat ttgtaaacat caataagttt
    41881 atataatcca cctatatagt tttttgctac ttcatggctc ttaaaaaatt catcttttcc
    41941 tgtatgtagg tttacttcca taattccctc cattgttctt atatttttaa ccttcaaata
    42001 atatttactt cttcttcaaa acagaatatt ctatcacggt agaatattct gtttttttca
    42061 ttctatcatg atagaataat attttcaatc attttttcta ttctatttta tttaaataga
    42121 atagaaaaaa agaacactta atatttttca agctaatata ttaagtgttc tttttatatt
    42181 tttacaagat tatataaaat tattctttaa tcaattaaag tgtttttcta tttcttaata
    42241 ataagaaatg atataaaatt gtatcatttt aaagattttg tgatataata aaagcaagaa
    42301 gaactacaat ctgtttaggc gtagagtgga gttcataata aacgtagttt attttttgaa
    42361 tttaaatata aatttaaatt caacctgtaa gtcactcttt gcacgagagt ggctttttgc
    42421 ttttttgaat agttcactga ttaagtaaac taccacacta gctgttaaac tagctaaaac
    42481 attaaacaaa aagttatcca tgtaactcac ctcccctcga atcgttggga ggataatctt
    42541 ttgtacatga actccactct atagattgta tattacgctc ttcttgctaa atttaattat
    42601 accatatttt gtaatatcag ttaagagttt gcactacaat aatcagaaag cttgttccac
    42661 tcacaatcaa cccctattat tttaagaata tcattgactt ggctatttaa atctttaata
    42721 tctgatttag acattaaagg atctttcatt atttcattta gaaaaatact atcaatgatt
    42781 aaacatacat tttctgataa atattcacgt tttactgaga ttactgttcc aactgtactt
    42841 tcttttagtg tcttatatgc tacactcaat atgcatggtt ctaaattaat tccttctagt
    42901 actgtttcaa agtaatattt tattcttata ttttcatttc caataaatat ttcttcattg
    42961 ctgcttatct tctttaattt tctcattatg cctaacatct tagcattcac ttcatagttt
    43021 attccacatc tctttgatgc taaactcgac atcaagtctc tttctgaata aattacccat
    43081 tgaccattat aggaaaatga tgttttagcg atatccattt ctccttttcc agtaatatta
    43141 aatttaggct ctagtttatt tattaagtaa atctcataaa aatccatagt atatttatta
    43201 tctaattcta tatactcaaa tcttaaattc ttattacacc aattttcttt tttattactt
    43261 aaatgactag cgtgtctatc gcagatattc tctgttttcc caacgtataa acattcttcc
    43321 gtatctagat taatatattt ataaacataa tacatttttt attttctcca attattattt
    43381 atagtaatat ccttcttcat ttactagacc ttgatcaaat aaatttctcc taacagtttc
    43441 aagtctgaca ggatctttgc tataatcaac ttctctttct tcttttttaa catcttcatc
    43501 atcccaatac ttatccaatt cttctttaaa ctttaaatca tctttttgat gaattataac
    43561 ttcacttatt ttatttgaaa gtgttgattt aaaaaaatca taattctttg tatttataat
    43621 atcagtatta tctctttcaa atgctatagc aatagactta ttaaaagcat tcagataaac
    43681 atctttctta aaatcaaact ctttaaaatc ttctttaaat agtttaatcg tccctgttgt
    43741 aaaaatattt tcatttggta tataaaaact aaaagacact tcattgtcct gcttcttttt
    43801 aggtatataa tcttcaacca atatatcttt atcaaaatat tttctaggtt cataatctat
    43861 cacagaaaaa attatttcat ctatttttct attttttctt ttttcttctt ttattgaaac
    43921 aaccatgttg ccttttttat ttatttcatt cattgctctt tttagaacat tttgtttaaa
    43981 atatttatac tctggatata cattatcttt taatttcaaa taaaatctta attcatctaa
    44041 cttatatttt atctccactt ccttattttc tctgctccat agtctaaata aagtgtataa
    44101 cctctgagta tatgcacctc taaaattaaa taacactgat aaattaatag ctgtatatcc
    44161 atttttcttt ttctgcattt ttacaaaatc agttatatga ttgtatagaa cttcatgcat
    44221 cataattgta taaatttggt ctgtatgatc caattcatat gtattaatta aaccacttcc
    44281 aaaagttttt aacttgccag ttgtctcttc tatatagtca aattccaaaa cactttgttg
    44341 aaacatgttc aaaatttctt ttatattttt atgctcataa tcattattgt ttttcataaa
    44401 tacttttagt tcttcttttg atatagttgt aacataagat gaattttgct gtttctgagc
    44461 attaaaaagt attttgtaaa ataatttatt ttccacattt gtaaaatcat atttactttt
    44521 tattaaatta tttggttgca ttaaaatttc ttttttttcc aaaatctatc acctcatata
    44581 aattataata cctaatttat aaaaaggtca accatttttg aaagacgctc acctttgacc
    44641 cttaaaatga tgacctttga cccttaaaat gatgaccttt gacccttaaa atgatgacct
    44701 ttcgaccctt aaaatgatga cctttgaccc ttaaaatgat gacctttgac ccttaaaatg
    44761 atgacctttc atctctgaaa cctagatata ccaattatta tagcttgtct aaaaactatt
    44821 aaagacttta aaaactgttt taaaaactat taaagactag aaaagatgtt ctgaactatt
    44881 ctttttttat attaaaaaac tttagtattt atttttctag tatactttaa acacttacta
    44941 aaaataattt cttataaaag attggagatg aagaattttt tatgcttgaa aacagaaaac
    45001 aaattcagaa agaaatttac ttaccaatag caacatattg tttaaaagat aagcaatatt
    45061 atataaaaga atatggagca ctattaataa agagtgctga aaatagtgac atttttaata
    45121 cccataaaaa tagaattttg tataagaata aacttgatat tcaagaaata gcaaatgaac
    45181 tgaatgtaaa taaagcaaca atccaaagaa atataaaaaa actagagaag ttagatttta
    45241 aaattctaaa aatagaaaat accctaaatg gaattgtata ttgtttacca tcagaaaata
    45301 atattgattt aaacaaattt gcattgataa attatgaaat gcttaaaaaa atggtcaata
    45361 aatttaaatc aaatacaata aaagtatatt ttttacttaa aacaatcact acagaaacta
    45421 attttaaacc tgcaactaat agttttatag cagaaaatat aggactaagt tctaaaagta
    45481 aaaataattt agatatcata acttcttctg ttaaaacttt agaagaaaat aaatacattg
    45541 aaacaaaaaa agtaaatgta tatgaatatg acaaagaaaa acttagagaa gttccaaaaa
    45601 taagaaaagt ttatcggatt tgtaattttg atgagtggaa aaaggaaatt gataaaaata
    45661 aagtttatta aatatagctt aaaagcattt aaaggcttgt ctgacgtgtt ttaattacaa
    45721 acttgatgtt atttacctaa aaagatacaa atttgcttaa aaatggaaat agaaggtcaa
    45781 atatataaat agagaaccaa ataaaattat attggctctc tatttatctt cttcccaatc
    45841 ctcaataaac ttttctaaac tttttaattt attttcagac acttcttcat catcatgcag
    45901 agcacttata aaactttcaa aagaattttt gtgaaagaaa ctaaagaaac ttttagtctc
    45961 aacttttaaa tattcttctt tttctattaa tgctttataa tatgtaaatc tatctttctt
    46021 aacaacctct aaaaatcctc taccaactaa tctcctcaag aaagttaaca tagttgattt
    46081 tttccattcg tacttttcgc ctagtgtctt caaaatttca gtagatgcaa cttctttatc
    46141 ttcgctgtcc caaataaaca tcataaccaa caattcactt tctggaatct tttttatctt
    46201 cataaagtac accaccttct aaaagtatat ctaaaatact ataacaatag agttaactac
    46261 acaatactaa atgtctaaaa atgttttacc aatttttacc aattaatttt tcttt
//
LOCUS       DAEHWO010000027        45019 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEHWO010000027 DAEHWO010000000
VERSION     DAEHWO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45019
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.027"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     misc_binding    111..322
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            485..1774
                     /locus_tag="KNP54_001788"
     CDS             485..1774
                     /locus_tag="KNP54_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBF0892690.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1828..2907
                     /locus_tag="KNP54_001789"
     CDS             1828..2907
                     /locus_tag="KNP54_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBF0892691.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2928..4472
                     /locus_tag="KNP54_001790"
     CDS             2928..4472
                     /locus_tag="KNP54_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBF0892692.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4635..5177)
                     /locus_tag="KNP54_001791"
     CDS             complement(4635..5177)
                     /locus_tag="KNP54_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBF0892693.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5325..5609)
                     /locus_tag="KNP54_001792"
     CDS             complement(5325..5609)
                     /locus_tag="KNP54_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBF0892694.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5672..6436)
                     /locus_tag="KNP54_001793"
     CDS             complement(5672..6436)
                     /locus_tag="KNP54_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBF0892695.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(6718..6984)
                     /locus_tag="KNP54_001794"
     CDS             complement(6718..6984)
                     /locus_tag="KNP54_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBF0892696.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(7026..7835)
                     /locus_tag="KNP54_001795"
     CDS             complement(7026..7835)
                     /locus_tag="KNP54_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892697.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            8148..8429
                     /locus_tag="KNP54_001796"
     CDS             8148..8429
                     /locus_tag="KNP54_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892698.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            8693..8947
                     /locus_tag="KNP54_001797"
     CDS             8693..8947
                     /locus_tag="KNP54_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892699.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            8992..9315
                     /locus_tag="KNP54_001798"
     CDS             8992..9315
                     /locus_tag="KNP54_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892700.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(9874..10068)
                     /locus_tag="KNP54_001799"
     CDS             complement(9874..10068)
                     /locus_tag="KNP54_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0892701.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(10442..12061)
                     /locus_tag="KNP54_001800"
     CDS             complement(10442..12061)
                     /locus_tag="KNP54_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBF0892702.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            complement(12370..12588)
                     /locus_tag="KNP54_001801"
     CDS             complement(12370..12588)
                     /locus_tag="KNP54_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892703.1"
                     /translation="MFFSLFKKKSGYTFTNFLSKVRVEKSKKYILKKDLSILDVAVLI
                     GFNSQNYYSIIFKKFNNFTPIEYKNIYN"
     gene            12881..13072
                     /locus_tag="KNP54_001802"
     CDS             12881..13072
                     /locus_tag="KNP54_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892704.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(13161..13973)
                     /locus_tag="KNP54_001803"
     CDS             complement(13161..13973)
                     /locus_tag="KNP54_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBF0892705.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            14395..15546
                     /locus_tag="KNP54_001804"
     CDS             14395..15546
                     /locus_tag="KNP54_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0892706.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVISDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            15664..16302
                     /locus_tag="KNP54_001805"
     CDS             15664..16302
                     /locus_tag="KNP54_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBF0892707.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            16303..17325
                     /locus_tag="KNP54_001806"
     CDS             16303..17325
                     /locus_tag="KNP54_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HBF0892708.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            17315..17935
                     /locus_tag="KNP54_001807"
     CDS             17315..17935
                     /locus_tag="KNP54_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892709.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGLALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(18059..18745)
                     /locus_tag="KNP54_001808"
     CDS             complement(18059..18745)
                     /locus_tag="KNP54_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBF0892710.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQNKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(18759..19304)
                     /locus_tag="KNP54_001809"
     CDS             complement(18759..19304)
                     /locus_tag="KNP54_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0892711.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            19532..20779
                     /locus_tag="KNP54_001810"
     CDS             19532..20779
                     /locus_tag="KNP54_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBF0892712.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLTFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            20866..22860
                     /locus_tag="KNP54_001811"
     CDS             20866..22860
                     /locus_tag="KNP54_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBF0892713.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            22860..24182
                     /locus_tag="KNP54_001812"
     CDS             22860..24182
                     /locus_tag="KNP54_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBF0892714.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            24461..25747
                     /locus_tag="KNP54_001813"
     CDS             24461..25747
                     /locus_tag="KNP54_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBF0892715.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            25833..27140
                     /gene="grdB"
                     /locus_tag="KNP54_001814"
     CDS             25833..27140
                     /gene="grdB"
                     /locus_tag="KNP54_001814"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:26880..26882,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBF0892716.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            27417..28148
                     /locus_tag="KNP54_001815"
     CDS             27417..28148
                     /locus_tag="KNP54_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892717.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            28150..29508
                     /locus_tag="KNP54_001816"
     CDS             28150..29508
                     /locus_tag="KNP54_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBF0892718.1"
                     /translation="MINLFSSDLFLKYSFFFSFIVYRILMVIVQYYFLINFTNFNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            29547..30032
                     /locus_tag="KNP54_001817"
     CDS             29547..30032
                     /locus_tag="KNP54_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892719.1"
                     /translation="MYLKRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKALQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKGKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(30295..30531)
                     /locus_tag="KNP54_001818"
     CDS             complement(30295..30531)
                     /locus_tag="KNP54_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892720.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTYKIQTAS"
     gene            complement(30687..30911)
                     /locus_tag="KNP54_001819"
     CDS             complement(30687..30911)
                     /locus_tag="KNP54_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBF0892721.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(31008..32261)
                     /locus_tag="KNP54_001820"
     CDS             complement(31008..32261)
                     /locus_tag="KNP54_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBF0892722.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            32521..33510
                     /locus_tag="KNP54_001821"
     CDS             32521..33510
                     /locus_tag="KNP54_001821"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBF0892723.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            33582..34322
                     /locus_tag="KNP54_001822"
     CDS             33582..34322
                     /locus_tag="KNP54_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBF0892724.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPSLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            34522..35673
                     /locus_tag="KNP54_001823"
     CDS             34522..35673
                     /locus_tag="KNP54_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBF0892725.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            35698..36453
                     /locus_tag="KNP54_001824"
     CDS             35698..36453
                     /locus_tag="KNP54_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBF0892726.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            36645..39032
                     /locus_tag="KNP54_001825"
     CDS             36645..39032
                     /locus_tag="KNP54_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBF0892727.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(39263..39496)
                     /locus_tag="KNP54_001826"
     CDS             complement(39263..39496)
                     /locus_tag="KNP54_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBF0892728.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            39785..40375
                     /locus_tag="KNP54_001827"
     CDS             39785..40375
                     /locus_tag="KNP54_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0892729.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            40489..41334
                     /locus_tag="KNP54_001828"
     CDS             40489..41334
                     /locus_tag="KNP54_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892730.1"
                     /translation="MIKVDDLSFSYTERDFLQNINFGVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            41331..42014
                     /locus_tag="KNP54_001829"
     CDS             41331..42014
                     /locus_tag="KNP54_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892731.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            42011..42727
                     /locus_tag="KNP54_001830"
     CDS             42011..42727
                     /locus_tag="KNP54_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892732.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            42824..43087
                     /locus_tag="KNP54_001831"
     CDS             42824..43087
                     /locus_tag="KNP54_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892733.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            43059..43514
                     /gene="def"
                     /locus_tag="KNP54_001832"
     CDS             43059..43514
                     /gene="def"
                     /locus_tag="KNP54_001832"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBF0892734.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            43566..44027
                     /locus_tag="KNP54_001833"
     CDS             43566..44027
                     /locus_tag="KNP54_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBF0892735.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            44077..44979
                     /locus_tag="KNP54_001834"
     CDS             44077..44979
                     /locus_tag="KNP54_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0892736.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSEGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
BASE COUNT        17518 a         4921 c         7200 g        15380 t
ORIGIN      
        1 atgaaaattt acatataaaa ctaaaaaatg caagtaattg actttttaag ttgacaaaat
       61 attgcatata tattatgata taaatcataa attaactaca aatcaatatt atatattcgt
      121 agaagaagaa agtagcataa aggaatttta cagagagtta gatttggctg agaactaata
      181 ttggaattta tgtgaaaagg actttggaga atactattgt aattatgtta gaatagtggt
      241 ttaattcgcc ttaagaaaat gagtgagtaa aattaatttt tactaataag agtggtaaca
      301 cggatttata ttcgtctctt ggatttttcc aagaggcgtt ttttattata aacttatttc
      361 agaaaattta aaactatata ttaaatgaaa attataaaaa tatgatagtt aataaattta
      421 taaattagaa aattgtaaaa tatgctaagg tcagtagttt tacgatttaa atggagggat
      481 gaaaatggaa gaagaaaaaa ttaactatgc tctggaacag attccagaga atcaaaaacg
      541 tggttgggta gctatgtttt cagttttagt agcaataggt gtggatttat catctgttat
      601 tttaggcgct gagttggcac agagtatgcc aatgaaacaa gcaatattgt cagtaattgt
      661 tggttcattt ttttctgcaa ttttgtatac tacatgctct ttggttggtt catctacaag
      721 tttatctaca tctatgataa caaagtatgt atttggagaa gctggagcaa aaatattttc
      781 tctagttata ggggtttctc tattaggttg gtttggagtt caagtaggtt tctttgctca
      841 aaatgcacag ataataataa aagatatatt taatttagat gtcagtatgc agattttaag
      901 cctaataggt ggtctcttga tgatgagtac tgcaatttat ggatataagg caatggagaa
      961 gttgagtgtg tattcagtac catttttatt agttcttatg atgctaacta tattcttagc
     1021 ttttagagca aatggaattt cagttgatga taatatgaaa tctactatga catttgcagg
     1081 tggagtttct ctgtcaatga gtataataat agttggtgca attgtatctc ctgatataag
     1141 tcgttgggct aaaagtagaa gagactgtgc tctttcaagc tttttgggaa tacaatttgg
     1201 aaatgctttt atgataatag tttcgatagt attagtaaaa tgtatgggaa cttcagatat
     1261 tatgagaatt tttattacat taggaattgc tataccaggt ataatagtac ttacattagc
     1321 acaatggact acaaatacaa gtaatgtata ttcagcatca ttaagtatag ctcttgtact
     1381 taagaaggct cctgagaaag tattaactat agtccttggt attatagcaa cattattggc
     1441 tgtatttgga atatatgaag gttttatagg atttttaaat ttacttggaa ttgtaattgc
     1501 acctgttggt ggtgtatata cagcagaata ttacatagta aagcaagaac ttaaaggctt
     1561 tgataaagga gtattatata aaccaatagt taaacgttca atagtgtctt ggataattgg
     1621 tatattaata acttaccttt caacatatgg atttataact cttactacta tagcaccttt
     1681 agatggtttt atagcagggt ttgtagtaca atctattatt ggaaaagtgc tttgttcaac
     1741 aaaaaataag caagaaatag acaaagcagt ataaagaaat ttgtttataa agtataaaat
     1801 aaattagaaa tatgaggaga aagtaacatg agatttttaa cagaagaaag tgtagataaa
     1861 atagcagttg gtgcagcagt gcttggaact ggaggtggag gtgacccata tgtaggtaaa
     1921 ttggttgcaa aacaagccat taaaaagtat ggtcctgtaa aagtaataag tttagatgaa
     1981 cttgatgatg atgctttggt agttccagta tctggtatgg gttctcctgt aattacaata
     2041 gaaaaattac tttcagaagt agagttaact acccctttag aaataatgga gaaattatta
     2101 aatagaaaag tggatgttat aattcctata gaaataggag ggataaactc acttatgcct
     2161 atagcagttg ctgctaaaaa aggacttcct atcttagatg cagattctat gggtagagct
     2221 ttccctgaag ctcaaatggt aactttttat cttgaaggat atgaggcatc tcctgccgta
     2281 atgtctgatg aaaaaggtaa ttctgccatc ctttatcctg tggatggaat ttggtcagaa
     2341 agattagcta gaactttaac tgtagaaatg ggaggaagtt cttctattag tgactataat
     2401 ttaagtggag ctcaagttaa aaaagctgct ataggtaata ctcttacaat agctgaaact
     2461 ataggagggt ttttacttga aaataaatct gattcaaaag gtgctgttga gaatatacta
     2521 aaagaattgt gtggatacaa gttatttgaa ggaaaagtaa ttgatattaa gagagagttg
     2581 aaaggtggat ttactagagg acatgccttt tttgctggga ttaatgagta tgatggagag
     2641 tattctatat tattccaaaa tgagaattta attgccaaaa aaggtgatac accactttgt
     2701 attacaccag atttaatagc agtattagat ttagaaactg gatttccaat aactacagag
     2761 agaataaaat atggctctcg tgttatggta gtagcttttc cttgtaatga aaaatggaga
     2821 acagaaaaag gaattgagac agttggacct ggatactttg gatatgatgt ggaatataaa
     2881 acagtagaag aattacaagg aaaataaaag tttaggagga aattttgatg tatcgtgtag
     2941 gaattgacgt tggaggaaca aatacagatg cttgtatact ggatggggaa ttaaaagtaa
     3001 ttcattcagt taaggtggca actacaaaag atgttgaaac tggtgtttac aatgccttaa
     3061 aaaaagttat agatgaaagt aagattgacc attcattaat aaaatatgct atgcttggta
     3121 caactcattg tacaaatgct attgtagaaa gaaaaagact taataatgtg gctatgataa
     3181 gaataggaaa gccggccact actgccattc ttccatttat agattggcca gaagacttaa
     3241 gagaaaaaat agaattagat tcaatattgg tatctggtgg atatgagttt gatggcagaa
     3301 aaataaatga actttgtaaa gatgaagttg tagagttttg caatagaata aaaggcaaag
     3361 tggaaagtgt tgcaataagt ggagtatttg ctccagtaaa taaacaacaa gaagaagaag
     3421 ttgcaaaatg ggttagagaa attttagggg atattcctat atctttatca aatgaaatag
     3481 gtaatatagg tatattagaa agagaaaatg gagctatttt aaattctgca ttgtctcaag
     3541 taggtaaagc tgtatcttta ggatttgaaa aagcacttaa agatttaggt atagatgctc
     3601 aaatatattt cagtcaaaat gatggaacat taatgaattt agagtataca atgaaatacc
     3661 caatttttac aattggatgt ggaataacaa attctataag aggagcttcc ttcttatcaa
     3721 aagtaaaaaa tgcaatagta ttagatgttg gtggaactac aagcgacttg ggtgtactat
     3781 ataatggatt ccctagagaa tcatctattc cagttacaat tggaggagta catacaaact
     3841 ttagaatgcc agatgtttta actattggtc ttgctggtgg tacatgtgta aaaggcgaaa
     3901 aagataatat aaagataggt cctgaaagtg tgggatatag aataactgaa gatgcaataa
     3961 tatttggtgg agacactcta actttatcag atgttgttac aaaattagat atggcgtttg
     4021 aagatagaaa aagcaatgtt gaaaacttag ataaagagta ttgtaatgag gtatataaga
     4081 aggttatttt aaaattagaa gatgctgtag accaaatgaa gactagtcaa gatgatgttg
     4141 aattggtttt aactggtgga ggaagtataa ttgttcctga aaaactaaaa ggcataagca
     4201 atgttataag acctcctcat tatactgctg caaatgctat tggtgcagct ttaggacaaa
     4261 taagtggaga tgtagaaaaa gtatacagtt tagataaaat gtcgagagaa gatgccatag
     4321 aagatgcaaa aaaagaggct gtaaataaag ctctaaaagc tggtgctaaa gaagatacta
     4381 tagaagtatt aaatatagaa gatgttccac ttgcatacct tcctggtaat gcacttctta
     4441 taaaagtaaa agttgttggt gatttaattt aaagaataaa tataagtatt tccagaatta
     4501 tataaatatt tctggactca tttttaaact tattttatca ataaaaacag cataactttt
     4561 gactatattc ttataagttt ccgaacagcc gatatatacc tattttttga ggtttatcgg
     4621 ctgtttgtta tcttttatcg cattccaact atttttctta ccgtatttgc tgtacgaatt
     4681 gtaatcttat cacttacatt tgaactggca gtctttgacc accaatttgt ctttttataa
     4741 tctttacgac taaaagacca aaagatagca tttttataat gatatacttt ttcatactct
     4801 tctttaggat ttccaacctc atcataaaac tcgtcataag ataagtcagg aaacataaaa
     4861 ataagattat catatatttc tttgttgtta tctccccacc aattaggagc attatttagt
     4921 atatctttta actcttcttg tgaaataata aaaactggta tttccaattc aaactgtttt
     4981 tttatcatta atcttattgt atttgagata accttgctgt catctacatc acttaaaaag
     5041 acaacattac cactattaag gtatgtagaa acttctgaat aaccaagttc tacaaagctt
     5101 gcttttaatt cagacataat tatcttgttc ttaccactta tattgatacc tcttaataat
     5161 gcgatataac ttttcatata ataatttcac ctctaaacat tcacattttt ctatgtagta
     5221 caaacttgaa tttgcatctt ttataattct ttcaaaactt cttcatatgt aattttttta
     5281 atataaaaaa atcggtgctt aatttgtacc gatttttgtt tttcctagta aagaactcgt
     5341 ttttttgctt ctgctatagc tctagcagca ctttttgctt gcattctttt ttcttcttct
     5401 tttttaaatt catttattgt ttcatttaga ttcttatcat gttcattttt ttctttatct
     5461 tcgttttctc tgtatactaa tatataatct attattgatt cgtttattat ctgagatata
     5521 cttttatttt cattaattcc tattctctta acttccttaa gtagagtctc atcaatatga
     5581 accgttgttt gctttgtatt ttttgccacc ttaatcacct cttaaaaaaa attctaacat
     5641 taaaattttt tttagtcaat aaattttaat attaaaattc tttaaatgtt ttatttgatt
     5701 ttctaaaatt ttctattgta tttatcatct tattttttat attttcacct agtacagaag
     5761 actttagtct aggattttcg atatggtcat aaattggttc taaaaattca acttcgacag
     5821 gaacagagtt aattttacca ataggttggt atccttcata agtatctttt gaatttttta
     5881 ttacgagtgg aacaataggg cattttgctt tatatgctat ctttaaagct ccacttctaa
     5941 actccgaaac caatgaattt ggttctttaa tccatgttaa atctccttct ggaaacactg
     6001 ccatactttg acctgtaagt atattttgag aggcttgggc tatactcttt ataccctcac
     6061 gattgttttt tctgtttaca tatacacatc ttagtaattt tgcccattct ttaaatatag
     6121 gtatatttct ccaaactggt tcatctgcaa ttacacatcc aattggtctt tctacacttg
     6181 ctgttagtat gaagctgtca agcatactag aatgatttac aacaaataga agtggttctt
     6241 ttggcagtgt ttccttacca attatattaa gctctatatt cactatatct aaagattttt
     6301 tagcttgttt ttgcataaat tcaaattttt cctttaagct aaatttatca ggattctttt
     6361 taattttaat aagcctaggt atagaagatg taaaacctat aagttgatat gtagcaaatt
     6421 ttaagtaatt attcataaaa ttatctcctt aaaataaaat tatttattac tgtaaagatt
     6481 ttaacataaa ataaaattta agtctatttt aattcaattt tgtaacatat attttaaata
     6541 gacagagatt gagattttat atttccaatt ttagtaatca gattttatca ataaattact
     6601 attctattaa tttaattaaa taacctttaa atttaattat aaaaactgtt gcagaaattt
     6661 ctacaacagt ttaaaaaatt taccttacaa aaacttattt tataacaaga gagtatatta
     6721 taaggctagt acagcccatt ttttgcactg agaaattctt ttgccatcat caccttgttc
     6781 tttgtcatat gcaaattgat taagcatttc acatggaaat gtatcacata gaccacaatg
     6841 tgtaaggttt ttatcttcac aacaagattt tacaggacat tgttcacccc aaaatggttt
     6901 ctcaatctct gtacaacctt tacaattgac tttttccttg tatccacatt cataacataa
     6961 aattccacat cttgattcta tcattttaag tcactcctta aatataaatt ttatatgatt
     7021 gtatatcaaa atttatactt ttcattgtaa aaatcggaca aattttttat ataggttgtt
     7081 ggattaacac cacaaataga tttaaaatca tttataaaat gagattggtc gtaataacca
     7141 atatcttgtg ctaaagttgc aaatggtatt ttattatttt gtatttcttg taatacaagg
     7201 tttatacgaa gtaatctaag gtatgattta acactcatac caagagaatt attaaaaatt
     7261 ctatttaaat gtcgttcact ataacaacta atttgtgaaa tgtttttaac agacataata
     7321 gagttttgtt ttctagcatt ttcaagaatt ggtatagtca tatctactat atttgatttc
     7381 aataagtatg ataagaataa catatctaat tgttctacta attcctttat agtacttgtt
     7441 ctttcaaaaa tggaattaac ctctaagcta aataatgtgt taaaatcttc aagtgaaatt
     7501 tttaaatctg tagattctct ttgagaaaga cctgtcaaat aatatactcc acctgggcga
     7561 aactcaacga atactctaaa aagtacattt tctatatcat tttttacaat agtagttttt
     7621 gttgtggctc cccagaatgc gctttctata ccttttttgt caaatttaaa tatcatacat
     7681 ccactagcat caggtattaa tgtaagattt tctttaatac ttgtatctgg aatagatatt
     7741 gtatagtgtg ctatatactg tcttaacaat ttatgtggca aaatatatgt atactgtttg
     7801 caggtattta aaatgttatt gattatttta ttcataagta tatcctcctg atatataaaa
     7861 aataagtata ctaatttatt ttttatataa taaaccagtt ttgttttaat tgaaatattc
     7921 taataagata ttttgttaaa tttagataca ataattgtaa agtaaaatct caaaatatac
     7981 aattattata aatcatagat atttattaaa taaatatatt aaagaagaag gaatataaaa
     8041 caagattaga aaataatagt gttactttca taataaatac atataaagat atttttaaga
     8101 ataaaattta ttattaaata aaaaataaag gagagtgatt taatagcatg gcatcaaaac
     8161 aaataccaag aaacaattta gaaaagtttt taagaataag agtcttatca catacaggcg
     8221 ataaaataca tataaagtta cctgtaaatt ttgcaaagag aatgattgag aataatgctt
     8281 tggatttatt taatggaaaa gatgatgtag tagatggtaa aaaagttact gaaatattag
     8341 ttaaggcatt tgactatgat ttaactggag aagtagttca cttggagaga aaaaatggag
     8401 acattattaa agtttcaatt gtacaataga attattttat atgaatttta tttttgaata
     8461 gttataaata attagaaatt tgtaaaaaag tataatatat tattagtaat ggtacagaat
     8521 acacatttat aatttataga tgtgtatttt ttgtttaaaa aatttaaata tataaaacta
     8581 taaaggttac aattttggaa atagatgtaa atatatgttg tattgtataa taagagtaat
     8641 ataaaatcta gtaaaaataa tcaaataaat ttagcttatg agagggataa ctatggaaaa
     8701 taaggatttt aaattaacaa tatgtatatt tgcttttgta attggagtag tagtattatt
     8761 ctgttgtata ggtttaggtg aatttagtgc agagcatatt attcaacaaa atggtggaat
     8821 catggatact gaccaatata atatttatct agaccaatct atttctcaat atagaaattt
     8881 tggttctata ttagctctgt taggaggaat agggatattg tttgataaat atatcagaaa
     8941 atactagaga ttatgttttg tctaaaataa attcttatga ggagataaaa aatggcaaca
     9001 gaaatattta ctgtaaaaat tacaccctta gaggcacaaa aaatgataaa agaaaatctt
     9061 gatgcagatt tagtttttag tgattcttat aatttaggag atgataaatt tatactaatt
     9121 acaacttttg agaagtatta tgcaagaaat aatagtgatg caggattaat agtagtttat
     9181 gaaaatacca caggaaaaac agttattaaa gctacttcaa caggcagtgc aattggaatt
     9241 ttaaaaattg attggggtgc aggtggaaat ttacttaaaa gagtaaaaaa catacttgct
     9301 gattatatta tttaattatt ttatctaact gataatatgt caagaaaatc tcgtaaaaga
     9361 ggttaagaac atttttataa tatatagata aataagaatt tgaaggtaaa gtttttaagg
     9421 tataaagaaa aataatataa taaaacgaat tggctttata attctttata aggcaaagag
     9481 cacatttctt tatataattg ttggatatta aataatatgt aaatacacca tttacatata
     9541 aaagtttaat taatatgtta agagaaaatg aaatggaaat tactaaaaaa tatttttaaa
     9601 ttggataatg gttgatatta tgtttataca aaaatcatgt agaattttat atattttaaa
     9661 tatgatagtt taaaattatg aaagaatgat aaattccagt ttgtagggta attttgataa
     9721 ataatattaa taagtatgag taaaaagtag gagcatatta atataatgtc cctacttttt
     9781 tattattaaa attgtttata atatcaacac tacattaaaa cacaacctaa atttgaaaaa
     9841 caaatagttt agaaatatgt acttttttat ctattatatt cttttaaatc gaattttttc
     9901 atctgaacat aaagtctcaa atctatatgc gtctgtcata tcataaaaac caaaaaatat
     9961 aaagccatca cgagaagtaa attcatattg tatattttca attttcaaca tgttttctac
    10021 ttcgcttatt ttttcgctat atataatttc taccatataa tttatcattg tagaatccct
    10081 cctattaata tgaaaatatc caaatatata ataacatatt tagatgatat aatagtatcc
    10141 aaataaaaaa taatattatt acattattga atgaagaatt aaaatgaaga taaataaaac
    10201 aaatattggt tataattgat taaaaaatag ttatgtatac ttgtgacttt atttatgggc
    10261 agttcaagtt ttatgaaaga agtcatatat atatggaata ttctaggcag aaactgttta
    10321 ataataagag aatactataa aaatttgagt attacataaa aaataagaag ccataaatga
    10381 tataagcatt atctatagct tcttacttct cattgattaa gattatatat aaaaataatc
    10441 actatatttt ttgtttaagt tttagtactt gttttactat atttgttgag tggtcagaaa
    10501 ttctttctag attagtaagt aagtcaagat aaagtacacc agcatcaatt gtacaacttc
    10561 cattatttag tctaatcata tgtgaatttc taaaagtttt ttctaaataa tttacttcat
    10621 tttcaacttc taaaacttta tttgctaact caaaatcttt aacatctaaa actattaagg
    10681 catccttaaa attagtaatt gtcttattgt atatttcgta tatttctctt atcgcactat
    10741 cagaaaaact aatgttcatt tccttaacac tcatggccaa ttcagctata ttttctgcat
    10801 ggtcagagac tctttcaatg tcatttacag tattaaaaag caaatctgtt ctaaagcgtt
    10861 catcatctct aagaggttct ttagaaagtt ttaacaaata gttcaatata tctttctgta
    10921 acttattgac aactttttct gactcaaaag ctttattaat atcttcattg ctcttattta
    10981 aaaatcctgc aattgaatgt tccaaagagt ttgtagcttt atgacccatt cttacaactt
    11041 cttgtacagt attaccaagt gctatagatg gagtgctaaa catcctttca tctaagtact
    11101 tagtattatt tactatttct gattcagttt ctttaatagg tataagtcta tttgctaatt
    11161 taactatgta tttagaaaat ggtaataata ttataacatt tgtaagatta aataaagtat
    11221 gtgcatttgc tatttgtcta gctgtatcag ttgggtcaaa atgagtaact atggctgata
    11281 taggtttatt taaaacaagc ataaatatta ttgtaccaat tacattaaaa cttaaatgca
    11341 ttacagctgc acgtcgagca tttctacttg caccaacact tgataaaagt gaagtaacac
    11401 aagtacctat attatctcca taaagaatag gtaaagcaga tgatagagga agtattcctt
    11461 gagaagctag tgctattaac atacccatag atgcacttga actttgaaca ataccagtta
    11521 tggcaaatcc tgccaatata cctaatacag gatttttact aaaatataaa agtgcatcag
    11581 tgaatgcttt atattcagca agtggagcta ctgcatcttt cataaactcc attcctgtaa
    11641 ataatatacc gaaacctata agtatctcag ataaatgctt tgttttttga tttgatgtaa
    11701 ataaatagaa taaaatacct atacctaaag caattggtgc aattccttca agattaaatg
    11761 aaactaattg agcagtaact gtagtaccta tatttgcccc cattattaca ccaatagctt
    11821 gacttagatt cattatacct gcatttacaa atcctacaac cataacagta gtagcacttg
    11881 aactttgtat aatacctgta acgactgtac ctaccagtac acccataaca acattacttg
    11941 ttaagagttc aataattttt tttaatttgt ctcctgctga tttttgtaaa ccttctccca
    12001 ttaaactcat tccgtaaaga aaaagtccaa gtccaccgat aaggctaatt actatattca
    12061 cgatatttcc tcccttaaga aattaataat ttttttatct gaattataaa ctttattaac
    12121 taaaatttat tgtttccata atatagaata acaaattttg tcaataaaaa tattaatgtt
    12181 ttgttaagta tacgttaaga gaatgttaaa tttttaagtt gttgttaatt ttagaaaatt
    12241 tatgatatat agcaatttaa atacttgaac ttagattttt agtattttat gtacaatcaa
    12301 tttaacaaag aattaactat aattgtaaaa aatatgtaaa aaaataacat ccttttagaa
    12361 tgatattttt tagttataaa tatttttata ttcaattggt gtaaagttat taaacttttt
    12421 aaaaattata ctatagtaat tttgactatt gaatccaatt agtacagcaa cgtctaaaat
    12481 agacaagtct ttttttaata tatacttttt gcttttttca actctaactt tacttaaaaa
    12541 attagtaaaa gtatatccac tttttttctt aaataaagaa aaaaacaact tttattaagt
    12601 tgtaattcat tacatatatt acttactgtt atatcttctg agtaattttt gtgaatataa
    12661 tctatagttt tctttaagtt ttctttacat aaaactaaga gttggtctat gtttcatttt
    12721 atcaaggcat atttattaaa aaatcaatct ctatttgtta aaataattta tgaatgatgt
    12781 tagaaactgt aatatattgg atataatata ataaacagat aaactctgta ttaagaggat
    12841 atatagttta tcttaattat aggggaagtg aggatatatt atggaaagat taatggaact
    12901 catagaaaga aaatttttaa aggatgtaga acttttagaa ttagaagaca tagaaaatgt
    12961 aatagaatgc aaaatgacac agccatataa tgctcattat aatgaatatt tagtaaaagt
    13021 aaaaaatgga gatgaagtag aagaatattt tgtgtattta aaacatagat aaacataaaa
    13081 gaggtttata tttatttgta tgattataaa ataaatacaa gcctcttttt ttgataaata
    13141 taaaattata aaatttttat ttatttaatt ttttcaacaa cattagtcaa tattgaatct
    13201 aaatcatcac taatttctgt aactccatta tgagtaatat ctataatttc tttagtcata
    13261 ggaagttctc ctaaaagctc taagtctaaa tcatctaaaa acttttcagt agattctcct
    13321 tcaaataact tgattttttt agaacaatca ggacattgga tataactcat attttcaata
    13381 actccaagga catttatgtt cattttttta gccatattaa cagcttttga tacaatcata
    13441 gataccaaat cttgaggtac tgaaaccata actattccac ttataggaat agattgcata
    13501 actgttaagg caacatctcc agtaccagga ggcatatcta ttaataaata gtctaattct
    13561 tcccaaagaa catcagtata aaattgcttt acaacccctc caagtaaagg tcctctccaa
    13621 acaacaggtt cattttcatc atctatcata aggtttatag acattacttt tatgttattt
    13681 gagttttcta cagggtaaat ataagagcca tcagaataag cttttacatt ttttacaccc
    13741 ataagtctag gaatacttgg tccagttata tctgagtcta atataccaac cttatatccc
    13801 attttgttta gcttattagc aagtaaagca gttacagttg attttccaac tccacccttc
    13861 ccactcataa caccaattat ttttccaaat ttattgttag ggttattttc aatagaacaa
    13921 tttgattgac tattacaatt tccctttgat ggacatgaat tacaatctgc catatctatt
    13981 acctccaaac tttaatattt attagattat ttgtaaccta catatactat tttagtacaa
    14041 ttgaaccata aagtcattat ttaaaagcaa cttagaagat tttctattga tttattcata
    14101 gactatagca aaaagaatac aataaaaaaa ttataacatt cttgaaaaag tgattatttc
    14161 aatttagtta tagaacttag tcatataaat atatagaaaa tattttaata tgttatacat
    14221 aacgggttat tttataagtt taactataaa ttaggtttat attttataaa aatttgctaa
    14281 aaaaaacaat taaaaattgt aaagaaaaaa gatataatta gaactgtagt aataaatgtt
    14341 ttattataga taatagagtt ttaagtatct taaataatat ttggaggaat atgaatggaa
    14401 ttaagaccaa gaagtgcaaa attagaagaa tttgataaag taatagaatt aataaactat
    14461 gtatttagaa tatcaagaaa tcataaacca actatgatgg aagaatttcc tcttttacta
    14521 agtaaaaata atatagaaaa tatgattata atatcagaag atgataaagt gatttctgat
    14581 gtaaactatc taattcagga tgtatctatt caaggaaaca gattgaaggt tgcagctata
    14641 ggtggagtat gtactcatcc agattatgaa aagagaggct attcatctaa gatattggat
    14701 aaagtagaag aaaaaatgtt ttatgatggt gtagatattg taattatatc aggaacaaga
    14761 agtctataca gtagaagaaa ttgtagtttg gtaaagagtt tttataaata tacaataaaa
    14821 cctgaagatg taaaaatagc atatgaaata gttgaatttg atgaaactaa ttttgaaaaa
    14881 gataatgatt tagataaaat gattgaacta tataatcaaa atagtactag atttataaga
    14941 acgagagatg agtttcaaaa actattgcat gcagcaacta ttgcctgggg accaattggt
    15001 tacaagaagg tatttataaa ggaaaataat aatataatag gatatttgat aataagaaca
    15061 ataaaaaaag aagattctac tgtaggagaa gttgctgaaa tagggttaaa ctctgtaaat
    15121 gttgaaaata tattgaaata tgttgcaaat aaatttggat tagaatattt aaattataaa
    15181 gtacatgtga aaaatcttaa agaccagttg aaatgtaatg ggacaaaatc tttggattat
    15241 caacaaggaa ctatgaaaat aataaatttt actaagttgt gtgatagttt aagaagttat
    15301 tttagtcaat atgtagattt tgaattacta aaatacatgg aatttaaaca agttgaaaat
    15361 aaatatatta ttaaatacaa agaagaagaa cttgtaatag aaaatttgga taagcttaat
    15421 aaactgtttt ttgaaaaaaa tgaggaacag tacaatgaat ttaaacatct aaaaaatata
    15481 tatgaatttg ctacaaaggc atttcctgta gattttccat ggactgcaaa tttaaattat
    15541 caatagtttt agatgatatt aaataaaatt gattgatacc tagagttagt ccttgttaaa
    15601 taagagaaat tattggatat tgaaaaagca attttgtaag taattagaaa ggatgagtat
    15661 tatatggaca tacttgatga tatagcagaa tgtatattaa atatgggtgt agataatata
    15721 gagaatttag taaaaattgc tatagataaa aatattgatg tggaagatat ttatgaatat
    15781 ggtttaaaca aaggtatgat aggagcttta gataagtttg agaataagga atactatctt
    15841 tcagaagtta tagtatgcac agatgcatta aataaaggta ttaatctttt gaagggaact
    15901 ggaaaagtaa agaaaaaatc aaagggagta attctgatgt ctgtagtaga aggagatact
    15961 catgagatag gaaaaaatat tgtaaaagta atggtagaag ccactggata taaggttatt
    16021 gacttaggtg taaatagaaa aagtgaagat ataatagaag aagctataaa aaacaatgta
    16081 gatataatag gcttatcttc aatgatgaca actacaatgg aaaatatgaa atcggttata
    16141 gacgaactta atatgattga gatagataaa agaccaaaag taataattgg tggaggacct
    16201 gtaagtatgg agtttgcaga agaaatagga gcagatggat acagttcaaa tgctccaaaa
    16261 gcagttaaat taataaataa acttatagga ggtgaagttt aaatgttttc agatatgact
    16321 ttacttcagt atataaatag tgaagataga ggtttttttc tgcctgatat gggtacaaat
    16381 ggattgttct taataaataa aaaggcatat gaagtatatg atagtgtaga tttgcaatta
    16441 gaattagcaa agactatgga caagtatttt gaatcagatt ttatatactc attctgtgat
    16501 gggattacat tttgtgaaac tctgggttta gagacattaa gaccagatta tgattttcca
    16561 agtgtattga cacatactat aactgacaga gataaattaa gaaaattaga tgttccagac
    16621 ccttatacga gtggacgtat gccactcaat atagagagct tatcagttat atcaaaaagt
    16681 attaaaaaac cactatatga atcgatacaa ggtccattta cacttgcagg tcaattagct
    16741 ggagctactc aacttttaag atgtataata actgataaaa aatttgtaga agaattattg
    16801 gaatttacaa ctgaattggt aagaagatat gctgtagctg caaataaagc aggagcaaaa
    16861 tatatttcaa tagcagagcc aacatcagta accctaagta aagatagatt tgatgaattt
    16921 atagtaaaaa atttaaataa aatctacaat gaacttgatt gttggaaagg tatgcatata
    16981 tgtggagaca ccagagaatt attagataat atgctaagtt gtaatataga tgcagtaagt
    17041 ttagaccaaa ttttagacta tgaagaaatt gctccaatga ttcctagaga tatagttttg
    17101 attggtaatt tagacccaat aaaacttctt ggacgttcta agccagataa gattagaaga
    17161 gagacgctaa aattgttaaa gaagatgaga agatatgata actttttatg tgattttggc
    17221 tgtaactgct taaataccac tccagtagaa aatttacaag cagctataaa ggcaggaaga
    17281 attagttata aagaattaga taggattgat attgatgaat tataatagta ataaaaataa
    17341 atatctttta aaggatataa atttagatga tatttttata gataagaata ttgtgctaaa
    17401 gtttttgggg tatggaaata gaaaagctcc agatacaatt agtaaaatcg ttgaaagaga
    17461 aataagaaat ataaatgata ttttagatat caagatatat ataagtgaag ttgatattaa
    17521 taaaacacct aaagaatgta aaaaagcatt tgctgtacta tatacaatag gggataaaat
    17581 tgatattaag atgaatgact atatggaaaa ttgcaatatg atggcagggc tagcattgga
    17641 taaaataggt atagtatgtt tagattatat taatgagaaa ataaaaatgt atttaaaagg
    17701 aaagtatgat agtctcaaaa tatcgcatga aatatatcca ggagataaag attttgaagt
    17761 agagagacaa aaggatattt ataactatgt aaaaaataaa tataatagta tagaaataga
    17821 aattaatgat tatcatcaac tatcccccat aaaaagtgtt gcaatgctta ttttaatggg
    17881 ggatgaagaa aatttagaat caagatgtag taagtgtcct agaaaatgct tttagttaat
    17941 tttcaagact aagatttgtt ttgtgtataa attgcaataa tttttttggt cattttatgt
    18001 ataaactaaa aaaattattg caaagtaata ttctatttaa tttgaacaga cttacaaact
    18061 atagtagttt ctttaattca ataagtgtat ttatttcata agttggtata tgattagtat
    18121 aatttatact gttattggaa tttaaccaac aagtatctat tcctgaattt attccaccta
    18181 agacatcaga ggttaagcta tccccaatta ttaaggcaga agatttatca tgacaattaa
    18241 actttttgag agcgtattta aatatttcag gatttggttt tgatattttc aactcttcag
    18301 atacaaccat tccatcaata tatcctttta tttttgaatt ttcaagtctt ttattttgaa
    18361 ctgcagaaat tccatttgtt attataacaa tagtatactt ttttttaaga tattgtaata
    18421 tatcgattgc acctggaatt aaaaatgtac attcacctaa aaaatttaag tacattttgc
    18481 taagagtttc agaatcaaca tccaaagata ttttatttgc aaaaagttca aatctaagta
    18541 atttaagttc attcaaagtt ataatatttt tttcaaggtc gagccaaagc ttatcactta
    18601 tatttctata tgactctata taattctcaa aattaaattc taaatcaaac tcagatagaa
    18661 gttttttaaa agcatgtgat tcacttttct taaaatcaaa taaagtatca tctgcatcaa
    18721 aaaatataaa tttatatgtc ttcatggttt ttactccttt acaagatgac tgcaaaaatt
    18781 actttacttt cactatttga gtcattttgc catttatgtt ttgttcctaa aggaactttt
    18841 acactatctc ctttggacaa agtaaattca tcatcatcca taaaaagttt aacttctccc
    18901 tccaaaacat atgcaatttc atctccatta tgagtaatcc tatcaacaca agaagaagtg
    18961 tttggagcta aatccataat tgcaaattct aaattaccac tagagtctgg aattaaaatc
    19021 tcatatataa cttctttgct tccaggtaaa ataacttttt ttctattatc atgtcttact
    19081 atcaagtttt ttttatctac ttcagataca aaaaatgtaa ataaaggaac atttagagaa
    19141 gaggctatag attttaatga atttacagat ggattagcaa gacctcgttc tatttggctc
    19201 aataatgatg gtgtaacatc agctagtttt gctaaatctc gaatacttaa gttttgtttt
    19261 tttcgaactt cagctatttt ttcccctaaa tttaaatcat tcatataaat atcctctctt
    19321 tttaatttaa aaaatattaa cttaaaataa tcaagtaaaa tgattatgta gtatgaaatt
    19381 attataacat atagaattag gttttgaaaa aactatgttc aatataatta aataaattaa
    19441 aatataattg acaaagtgga tacagaatac ttaaaatata tttaaataaa attaagcaaa
    19501 agatagttaa tttatgatag gaggggatat tatgcaaata acgacttttg gagctatatt
    19561 tggtttatta atagcaatta ttttaattat aaaaaaattt caagctgtat atagtttaat
    19621 gttaggagca tttattggag gattagttgg aggagcaaat ataacacaaa ctgtagattt
    19681 tatggcaaat ggagctatga atatatcacc atcaattctt agagctttgg catcaggtgt
    19741 attagctgga agtttaataa aaacaggggc agtagataaa atatcagaac agattgtaaa
    19801 aatatttggt gaaaagaggg ctttattttc gattgccatt tcaactatgg tacttgctgg
    19861 agtaggtgta aatttggatg tatctataat aactgtagca cctataggat tatatatagg
    19921 tagaaaatta aattattcta aattgtcaat actattagct atgttgggag ggggtaaagc
    19981 aggtaatata atatcaccaa atccaaatac tatagcagta gcagataatt tttctgtcaa
    20041 tctctctagt gttatgatgg caaatataat tccagcaatt attggagttg ttattacagt
    20101 tattttagca agtatattaa taaataaagg aaataaagta caatcatatg aaattttaga
    20161 gcaaagagaa gatttaccaa gtttatttaa atcattatgt ggtccaatta tagctatatt
    20221 tctattgttt ttaggaaatg tatctcctat agttatagac ccaatgatag cccttccaat
    20281 aggaggaatc gtaactctaa ttgtcacagg aaacttgaac aattcaagag aatatttaac
    20341 ttttggatta tctaagatgc aaggggtatg catattatta cttggaacag ggactatcgc
    20401 aggaattata cagatgtctg aattacaaca gagtacaata ggtgctttac aatttttaaa
    20461 tatgccacaa tttttattgg caccagtttc gggtatactt atgtcattag caacagcatc
    20521 atcaacagct ggtgctacta tagcatcatc tacttttcat gatgctataa taaatggtgg
    20581 gctatcaccg atttcaggtg catcaatagt aaatgctggg tctagtgtat tcgagcaatt
    20641 accacatggc tcactatttc atactagtgc aggtagtata aacatggata taggtgaaag
    20701 atttaagtta attccatatg aagcattgat aggaatagta atgactataa tttcaacatc
    20761 tattcaatta gttttataat aaatataaat atttaatgaa aaaagtagga ttttgttatt
    20821 aaatattgaa cttattatag taaaaaagaa gattggagtt ttaaagtgaa taaaaaaaag
    20881 attgttatta tagggattat ttattcattt ttagtagtat tttcacttac aaatatgtat
    20941 gtaaatatgg agtataatct aaatgtattt gaatatatta agaagtcact tccatttaca
    21001 gaagaagaaa aaaagtggtt agaaaaacac aagaatttga tttacagctc tgaccaaagt
    21061 tcacctcctt tgagatataa aggtaaggaa gatggacagt ataagggaat tattgttgat
    21121 ttaataaatt ctctgtcaat tcaaattggt agagattttt attttaaacc aaataattgg
    21181 tggaaagaat ctttcgtaaa ttcaatagat gatagtataa agttttttga cttgattcca
    21241 tcaaaagaaa gggcaaataa atttatattt actgacccaa tatacacttt gagtgcaaat
    21301 atattgaaag ataaaaagtc ccaagatata aatagttaca tggatttaaa ggggaaaaca
    21361 gtagcaattc cagaaggtga ttattctata aattttttaa agcaaaaaat tcaagatata
    21421 aacattttat tgactccaga tataaagact ggagtcaacc atttaatgtc tggaaaagta
    21481 gacgcagttg ttggtgatga accagtattg cgatactata taaataatta tggactttca
    21541 aataaataca gtgttttaag taatcctata tatactaaaa aagcagttct tgctgtacct
    21601 aaacaatatg aagagctggt tagtatttta aataaaggca tttttaaact tcagaaaaat
    21661 ggagtgtata aagatttaaa gaaaaaatgg tattctacgt ataatgaagt tgatgatata
    21721 ttgtatgagc gaggaattgt gcctagtatt tatcttttta taggtataat tttaatatca
    21781 atttatgttt tttatagcta tacatatttg ttaaagatag aaatcaaaag gaaaacagaa
    21841 caggtaatag aaaataaaaa aactttagag gcaactttta atagtattac agatataata
    21901 atgcttgtag atgaaaataa caatatagta gaatcgaaca aagtactata tgactttatg
    21961 ggtgaaatga gttataagat agcagatttg attagcatga taaaaggtgt tattgaaaat
    22021 accttctctg aaaatactaa taaaactagt gaaatagaaa tacacaataa aattttaaag
    22081 ataaacactt ttcctgtaga gtataaaaaa aataatactg agtatatagt agttcttatt
    22141 aaagatataa ctaatgataa aatagtagag gcgaaattac ttagagaaaa caaaatgata
    22201 tctatagggc aattagcttc tggggtagca catgagataa gaaatccttt gggtataata
    22261 agaaataatt gctatctctt aaaagataac gttacaatgg aagaagtaaa tgattgtgtt
    22321 aaatcaatag aaagtaatgt agatagggca agtaatataa taaccaactt gttaaatttc
    22381 gcaagaatat cagatgataa tttagaacat ataaatataa aaaattttat tgaaaatata
    22441 gtgaaacttc aatataaaat gttacagtta aagaatgttg aaataaaaat tgactgtgaa
    22501 cataatttaa tatgctatat aaatggagaa tcgttaaaac atgtatttat aaatttaatt
    22561 tctaattcaa tagatgcaat acatcaagat ggaaaaatta ttatatactg ttatgaaaaa
    22621 aatcattgtt tatttataga ttttaaagat aatggtgaag gaataaaaga agatgtccta
    22681 aaggacatat ttaatccctt ctatacaaca aaaccaattg gtgagggaac tggtttaggt
    22741 ttatatatta cttataatga gattaaaaag aataatggag atataagtgt tgaaagtaaa
    22801 ttgggggttg gaacttgttt tcatataaaa attccattaa ataaagaggt gactatataa
    22861 tgaaaatact attagttgat gatgagctag aatatggagt ggtaatgaaa aaaattctac
    22921 aaaagaaggg ctatcttgta gatatagcac taagtggtga agaagctata aatataatta
    22981 aaaaagataa aaattatgat ttggttttat ctgatgttat gatgaaaaat atggatggag
    23041 tacagctatt agatagaatt aaatctatta atagagatat agaggttata ttagttacag
    23101 gatatggaag tattgaaaat gcagttgatg ctatgaaaag aggagcttta tcttatttta
    23161 taaaaagtaa tcccattgaa aatttattag aagaagttga aaaggtaaag gcaagtaaaa
    23221 tatctgtttc tgtacaaaaa aataattttg aatttacttt ggaatctaaa aatagagatt
    23281 ttaataatat cataaaaata gcaaaaaaag ctgcttgtaa agatgttaat atattaatct
    23341 tgggggaatc tggtgtagga aaagatatat tagctagata tatacatagc ataagtccaa
    23401 gaaagaatga gatatttgta cctgtaaatt gttgttcttt ttcagaaaat ctattggagt
    23461 ctgagctgtt tggtcatgaa aaaggttctt ttacaggagc agtagatagt agaaaaggta
    23521 gatttgaact ttcgaataaa ggaactctat ttttggatga aataggagat atacctctaa
    23581 atgttcaggt aaaacttttg aggacacttg aggacaaatc tatagagagg ataggaagta
    23641 ataaatctat taaagttgac tttaggttaa tttgtgctat gaataaagaa ccaaaagtgg
    23701 aaatatcaaa tggaaatata agagaagatt ttttttatag aataagtaca ataacaataa
    23761 ctataccacc actaagaaag agaagagaag acttaactac tcttatagaa tttttcttaa
    23821 ataagtacca aattgaacat gataaaaaga tacactcgat tgataaggaa gtaaaggatt
    23881 ttttattaaa ttacaattat ccaggaaata taagagaatt aaaaaatata ataaatagac
    23941 ttgtagtttt aagtgaagaa ggtaatttat caaaagacaa tttaaattta atatcaaata
    24001 atgtatacat agatgataaa ataagtatta gacctttaag agaaataaga aaagagtttg
    24061 aatgtgagta tattgaaaaa gttttatctt tgtgtggaaa taatatttca aatacagcta
    24121 aaaaattgga gattagtaga agacagttaa ccaataaaat atcagagtat aatattaagt
    24181 gagaaaaaaa cttctcatta agtgagaaaa aaatttctca aactgtatta aaagataaac
    24241 agaaaaaatc tgtttatctt tttttattat aattttaaaa attaatattt acaataatta
    24301 ttgctaaatt caatattggt gtaaattaaa aatgaaaatt tctatgacat taatacatag
    24361 aatatatatt ttaaataatt ggcatagaaa atgctttata tattaataaa cgtaataaat
    24421 acttttaatt gcgattaaat atattaaggg ggattttcat atgaagctag agctagggaa
    24481 tatatttata aaaaatgttg aatttggaga aaagacagaa gtaaaagatg gagtactata
    24541 tattagtagc gaagaaatag aaaagatagt attagaagat gaaaggattg taagtgtaaa
    24601 tgttgaactt gcaagacctg gcgaatcaat aagaatagct ccagttaaag atgtaataga
    24661 gcctagagtt aaaattggag atgaaagcaa aatatttcct ggaattataa ataaagtgaa
    24721 gactgtagga agtggaagaa cccatgtact tttaggagct tgtgttgtaa cttgtggaaa
    24781 tatagttgga tttcaagaag gcgtaattga tatgagtggt cctactgcta aatatacacc
    24841 tttttcaaaa acaaataata tatgtattgt tataaaagca aaggatggta tagatactca
    24901 tgattatgaa gaagcagcta gaattgcagg attaaaaata ggtgcatatg taggtgaggc
    24961 aggaagagaa gttgagccag atgaagtcat tgtatatgag acaaagccat tattaaaaca
    25021 agtaaaagaa tatccagacc tgccaacagt agcatatgtt cacatgttac aatcacaagg
    25081 acttttacat gacacttatt actatggggt ggatgctaaa cagatagtgc ctacatttat
    25141 gtatccaact gaaataatgg atggagctat aatatctgga aactgtgtag caccatgtga
    25201 taaggttaca acattccatc atttaaataa tccagttata catgacttat ataaaagaca
    25261 tggaaaagat ttaaacttta taggagttat tttgactaat gagaacgtat tcttagtcga
    25321 taaagagaga agctctgata tggtagctaa attaatagaa tttttaggag ttgatggagt
    25381 tctagtgaca gaagaaggtt atgggaatcc agatactgac ctaatgatga attgtagaaa
    25441 atgtagtgaa gttggagcaa atgtagtttt gataacggat gaatttcctg gaaaagatgg
    25501 caagagtcaa tctatagcag acgctactaa ggaagcagat gcagttgttt cttgtggtca
    25561 aggaaatcta gtggttcatt tcccagcaat ggaaaaaatt ataggaactt tagattatgt
    25621 tgaaatgatg ataggtgggt ataaaggatg cttaaatgaa gacggaagca tggatgcaga
    25681 gctacaaatt ataatagcat caactatagc aaatggctat aatcatttga cagcaagata
    25741 ttattaaata agtatttgaa tataaagttc tgttgatgta atcattggtc taactgatgt
    25801 aataactata aagtgatttg gaggattaag agatgagtaa aatcagagtg gttcattata
    25861 taaacaattt ctttgctggt ataggtggag aggaaaaagc agatattccg ccagaaaaaa
    25921 gggctggtgt agtaggacct ggaatagcat ttcagagtca atttaatgat gatgcagaga
    25981 taatctcaac tgtaatttgc ggagatacgt attttggtga aaatattgag agtgcaactc
    26041 aagaactttt aaaaatgata aaagaagaaa gccctgattt atttattgca ggcccagcat
    26101 ttaatgcagg tagatatgga gtagcttgtg ggactatttg taaggcagtt gaagaagagt
    26161 taaatattcc tgtaattaca ggcatgtata aagaaaatcc aggtgtagat atgtttaaat
    26221 tagatttgca tatagtgtct acaggaaatt cagcagcaag tcttagaaag gtagttccaa
    26281 taatgacgaa actaggtctt aaattggtta gaggtgagga aataggacct cctgaagagg
    26341 aaggatatat aatgagagga ataagaaaaa atttcttcca tgaacttaga gggtctgaaa
    26401 gagcaattga tatgttggtt aaaaagatga aaggggaaag ctttgaaact gagtatccaa
    26461 tgcctgaatt tgatagagtt acacctatga aacctgttaa agatttatct aagataaaac
    26521 ttgccctagt aacttctgga gggatagttc caattgataa tccagacaaa attgaatctt
    26581 caagtgctac taaatatgga atttacgatt taacagatat ggattctatg tcaaataaag
    26641 aatttacaac tatacatggg gggtatgaca gagcatatgt ccttgaaaat ccaaatttag
    26701 ttgtaccact agatgtagtt agagagcttg aaaaagaagg tgtaattgga gaattagtag
    26761 attattttat aactactaca ggaacaggaa cgagtgttgg caattctaag agatttggag
    26821 aagagttttc taagaaattg ttagaagatg atgtagatgc tgtaatttta acttctacat
    26881 gaggtacttg tactcgttgt ggagcaacga tggtaaaaga gattgagaga gctggtatag
    26941 cagttgttca tatatgtaca gtagtaccaa tatcacttac aataggagct aatagaattg
    27001 ttccagcagt agggatacca tatccacttg gaaatcctat gttaggagaa gaggaaagta
    27061 aaaaaattag aaagaatata gttttaaaag ctttaaatgc actaacagaa gatatagaag
    27121 aacaaacagt atttgaataa taaaaataca acacaacact gaaataaaaa aagatatcaa
    27181 aaaataattt tttaaaatta ttttacgata tcttttttta ttaggtaaat tcgaaatttg
    27241 cattttttta aattaaattt ataaaagtga taaattagtt tattataata ttgatacaca
    27301 aattcaaatt agatatacta tgaaaagcga gattattaca ttttggaaca aatattcaac
    27361 atattagatc atattaattg aacagaaaaa attaacttta tataataatt agaataatga
    27421 taagaaagaa ggtgtatata ttgatttcaa ttgccatttg tgatgatgaa tcctatatgc
    27481 taaatcattt aaaggaaaat atagaattat acatgaagca gaagaattta ttatataata
    27541 tagagctttt taataaagta gaagatttac tatgcaatca tgaaaagttt aatattgtat
    27601 ttttagatat acagatggaa gagattaacg gaatgcaggc agctagaaaa ttaaggtcat
    27661 atggtaatga gtgctttata attttcgtta cagttttaaa tgaatttgta tttgatgctt
    27721 ttgaagtaga tgctataaat tatctgataa aacctctatc taatgagaaa ctatataaaa
    27781 ctttggataa aatagttaca aaacttgatg ataatgaaag taattatatc acaatacaaa
    27841 aaggttattc atattggaaa ttaaaacttg ctgatatttt atattgtgaa gttataaaaa
    27901 gaaagattta tgttcattta aagaaagaga ctgtagatta ttatgagact attgaaaatt
    27961 tagagagaag tttaccaaca aattttttta ggtgtcatcg tagttatata atcaatttac
    28021 aatatgtata tggatatgaa aatggtaatg cagttatgga aagtggagat agaatacctg
    28081 tttctagact acgtcaacaa atattttcaa aagttatgct tgagttcatg aaaaatagga
    28141 ggatataaga tgattaattt attttcttcc gatttatttt taaagtacag ttttttcttc
    28201 tcttttattg tatatagaat tttaatggta atagtgcaat actattttct aatcaatttt
    28261 acaaatttta attcaaaatt ttggtgtttt attttatatt cgataatttc aattttttta
    28321 atcattataa atacatattt taatttatat aatttatttt cttcacagat tctatttttt
    28381 cttatgactt ttttatttgt aaagtacata ataaaacaat ctactgtttt atctatagta
    28441 tcaactttgt tagtatattt aattgaacaa ttagtatatg gatttacagc tccattaaat
    28501 tacttgatat ttactagtga tataaataca gatatttata aatttgatat aaatatggga
    28561 ctatcttctt taattactat tataatagct ggatttatat attggtatag ttctaaaaag
    28621 tttaatatta aggtcatgaa ctttgataaa tatatagcaa ttttgatgat tccattgttg
    28681 cttataatat tatttatgca atcatttgaa tatagttcaa atataaatat agatacaagt
    28741 cttgggattg taaagctgct attaaatact tctataactg aagaaattca agcttttctt
    28801 ttttctataa ttggaactat atgtgtattt ttttctctat ttacctttaa gaaactaatt
    28861 caagctctcg aagatgacaa ggagagggca attatgaatc aacagattca tgctcaaaaa
    28921 aactatattg aagaagcgaa atcacgatta tcacaaacta tatcctttag acatgatttt
    28981 aataatcatt tagctattgt caatggattg ttgaaaaaag accaaatttt aaaagcacaa
    29041 gattatttaa ataagcttga aaaagtaaca agtgacctat cattttcttg taatacacag
    29101 aatattgtta ttgatgctct tttcaacaat aaattaagta tagcaaaaca attaggcata
    29161 gaggtagatt gtgaagtaat tataccccaa agcactaaca tgaacgattt tgacctatgt
    29221 atagtgtttg ctaatgctat tgacaatgca attaaagctt gtagagttgt agataaacaa
    29281 aataggtatt taaagctttc cactaagtta gagggtggat tttttatgat agaaataaaa
    29341 aatagctata atccaataaa taattataca agtggctcag gtataggtct tttaaatata
    29401 aaagaaattg ctaaaaaata tcaaggggct ataagtatag ataagacatc agactatttt
    29461 caaataaatg tattgctagt tatttcatta cattgcgcta gtatttgaga acaatttcat
    29521 tgaaaatagt atttgtaagc tatattatgt atttgaaaag agaaagtttg atatatagaa
    29581 atgaggaggt tactaaaatg aaagttggaa atataaatgg tcaagcacca attacaaatg
    29641 gtttagatag ttgtcaaagt gaggtacaag gcttagaaca aaagaaaaaa gcattacagg
    29701 atgaaataga gaaagtaaga agtgataaaa gtattgatgg tgaaacggcc aaattaaaaa
    29761 tagaagcttt aaaaaaagaa atggaagaga ttgaaaataa aattcaagag ttaaaaggaa
    29821 ataaaggaaa aaaaacaaat aaagaagaaa ataacgtttc agaagtaaat aataatctat
    29881 tagagagaaa aaaagaacct tctaataatg aaaatgtaaa acaattatat gatgtttttg
    29941 aaagaagcaa tgtagacgaa caatgggata atacttatcg tgttctccaa gatgataaaa
    30001 acttaaaagt aaaatttaat agacctatat agtttattta taaaaatagt taatatttta
    30061 attatcacca ctttttagaa gaatacacac tttattttaa agacccacat atttatttac
    30121 agttagcaca tttatatgtg gttttataac tattatttac aagtctatat tgataacttt
    30181 tacatagtat atgatgttta aatacttatt caaatttatc tatacataaa caaaaaaaga
    30241 gattttaaaa tctcttttta gattgttgac ttatggcttt ttgatttaat aaaatcaaga
    30301 agccgtttga attttatatg ttggctgata cccttctgat attgaaacac catttttgtt
    30361 tccaaaatcg tttaaaatta agaacttatt atgaatgact atttcattat gaacaataag
    30421 caaataacat gaatcttcaa tcaatgtttt aacagtagca ttaaatgctt gcttatatag
    30481 ttctatcgtt tgtttgaact gcccattaaa gtaaatatga gtcaataaca taactatatc
    30541 tacacaaatt aatataaatt ttttatactg tacattatct aactgttgat tatctgtatt
    30601 acaacatgat tgaatttaaa aagccatcaa cacatagaat gttgatggcc tgaaaataga
    30661 ttttaaaatc tcttttttat tatatattaa ttatttttta aatttatatt ttttgcatca
    30721 gattttctaa tagctaagtc aaaccctcta aatctaatca ctatagggtc attaagagga
    30781 gctatctttt tcacttcaac ttcagtgcca tctattagtc ctaaggctag aagtctcttc
    30841 ataagttttt catttccagc tatattgtct ataattccct tttgtccaag ttttaagttg
    30901 taaacagtca ttattaacac ctcctaatga aaatcattat caaactttat atttataata
    30961 tataacaaaa agagcaaatt gtcaatatat aacaaaaaat aaacatacta agttagtatg
    31021 tttataaaaa atagtataca tgggatacta atagcatcta gcaaaaaacc acttactaat
    31081 ggtacaacta aaaaggcttt tggagaatca ccatattttt gtgtcaaaga actcatattt
    31141 gccagagcgt tcggagtagc tcctattcca tgtccaatca aaccacttat tatgatggca
    31201 gaatcaaaat cttttccaag tactctaaag caaataaata ttgaaaatag gattataaag
    31261 attacttgaa aagttactat taagagaata ggaggtaata atgtagataa ttcaaataaa
    31321 tctatattca taagtgataa agttaaaaaa attcccaatg aaagttcttt taaaaaatct
    31381 ataagtttaa aatttaattc tagtatattt atcttatcat ttaaatttct aaaaataaca
    31441 gccgaaaaca tacaagttac aacagagggt aatagtatat taaacgttat atagaagcat
    31501 ctacttataa tttctcctgt atttatacaa ataaatatga gaagaacctg ttccaaaaat
    31561 acagatggtg ttattgtttc ggagaagtta ttatttttta tcctattctt atttctaaaa
    31621 aatttacttc caaatctctt tagatttcta ttatatctag gaatcgacaa gtctatattt
    31681 gatgatggtt ttaatttata tttatttatt agaaatttag ctacaggaca tcccaatata
    31741 ccacccataa taagtcctat tgttgcagca gataatccaa ccccaactgc tccttctata
    31801 ccaagatttt ctattgtaag tccaaatgca gcagaataac catgaccacc ttccatagat
    31861 acatttccac acataagccc taaaagaggt tcaagtttta taatctttga tattgtaata
    31921 gctaatatat tttgacaaaa tgccaatact ccacacaaaa tccaatatct aaataataca
    31981 ctaccacctt tctttataag atttatgctt atttcaagtc ctatagttgt aaaaaagaag
    32041 gttatgaaat ttggcattaa atttccactt atagatatat ctgctatatt aaaatattta
    32101 aaaaataaat ttagaaaaca aaataataga cctcctatta ctggtgcagg tatacagaaa
    32161 ttatttaaaa agttaacttt attcttcaat aaattaccaa ttaaaaagaa gaatatagat
    32221 agtgtcaagg tttgcactat atcaaaactt aaggtaatca aaataagtcc tcctttgtaa
    32281 ttcaaagttt taattatata acttaaattc ttatgtattg aaattttatt atcaaatgta
    32341 tattaataaa tgtatattaa aaagaatcag tagatataat tagatagtca taaattaaat
    32401 taaaatattt taatgagata tgactttttt agaattaaaa accgtagtat attgatataa
    32461 tagaaataag acttaaaaat ctgttgatag tattatttat aagtacagta ggaggataaa
    32521 atgtttgaaa atttacctaa gatagattta cattgccact tagatggaag tgttagagta
    32581 gaaaccatgc ttgatatagc tattaaagag aaaatagatt taccttcaaa taatatggat
    32641 gaaataaaaa aattagcaaa ggtttctttt aattgtactt cactagatga atatttagaa
    32701 aaatttgatt tacccttaaa agtaatgcaa tctaaggaaa atttaaaaag aattactttt
    32761 gaacttttgg aagatgcaag tagagaaaat gtaaaatata ttgaaattag atttgcacca
    32821 ttacttcaca cccaaaaagg tatgagtgtt aaaaatataa ttgagggtat aattgaagga
    32881 attagagaag ctgaaagtat ttatgatata aaaggcaatt taatattagg ttgtatgaga
    32941 acaatgacct caaaagaggc attattagta attgaagaag ggaaatcatt tgtaaataaa
    33001 ggtgttgtag cagtagactt gtgtggtcca gagaaagagg gattttgtaa ggaatataaa
    33061 gatgttttta aattagcaag agaatatgga tataaagtta caatacatgc aggagaagct
    33121 gcaagtggag aaaatgtatt ggatgctata aatattttaa aggcggatag gattggtcat
    33181 ggggtaaaaa ttaaagacca taaaaaggcg tataatttag ttaaagataa aaaaatattg
    33241 cttgaattat gtccaactag taatgtacaa actaagacag tagattctta tgaagcacat
    33301 ccattttata ctttttataa agataattta catgtaagta taaatactga taatagaact
    33361 gtatcagata taaatttaag ttcagaacta aatgttatat ttgatacttt taaactagga
    33421 ttagaagact ataaaataat ttatagaaat gcagtagaag ctagttttgc agataaagaa
    33481 actaaagagt atttgaatag tttaatttaa tagataaaaa tatttaaact ttaaattaag
    33541 ctattaaatt gataaaaata cattgtatta ggagaaaaaa tgtgaaagat tatgaagatg
    33601 ttgtttatat taaactagtc aaaaaagaac ttgaagaatg gaagaaaaat atattaaaga
    33661 aaccttctat atttgacaaa gcatcaaagg gtatacagaa taaatttaat ggagtattgc
    33721 cagataaata tcatgaaata attacttctt ctataaaagt aatgacaaaa accgtactgt
    33781 ttggatataa atatgctaca aagccatcac ttagaaatat gtcattagaa gaaagagaaa
    33841 aattagtttt agaaaaagct aaaacttaca agactacagc aatgattgaa ggggcaggaa
    33901 caggggcagg aggaatcctc ttaggtttat ctgattttcc tttgctttta ggtattaaag
    33961 tgaaattttt atatgatgta gcttcaatat atggatatga tgttaaagat tatagagaaa
    34021 ggatttatat attaaatata ttacagttgg ctttttctag tcaacagcat ataaacaaaa
    34081 cttttaaatt gatgaataac tgggatgaat atgtaaatag tctaccagaa gacatcaatg
    34141 attttgattg gagaacattt caacaagagt atagggatta tttagattta gctaagtttt
    34201 tacaactaat gcctggaata ggagcatttg taggatttta tgtgaatgga aaattaattg
    34261 ataaattatg tgaaactgct gtgtctgctt atagattgag gattcgagag cttaagttat
    34321 aagagaaatt ataacataaa aaattagtta tacaatatat ctatatgtat ctaattttgc
    34381 attgataaaa acaattatgg ataaaaggta aagcatgata gaatctaatg tagaggtttg
    34441 tattttaatg gaaaaattta gtttttattg cttaagatac aaattgaatt acgaagagaa
    34501 gtaattggga ggaatatttt catgacaaat ttgccaaaac aatttgatag cttcaatgaa
    34561 gctagacaaa aaggatttat aaatgcaaag gaacttaagg aaagtgggaa aaagatggtt
    34621 ggagttttct gtacatttac tccagttgaa attccaatgg cagctggagc aactgtagta
    34681 ggtgtatgcg gcgttagtga agagccaata cctgatgcag aaagggtgct tccaagaaat
    34741 ctttgtcctt taattaaatc aagctatgga catgcaataa cagatacctg tccttatttc
    34801 tatttttctg atttgttgat aggagaaacc acttgtgatg gtaagaaaaa aatgtatgaa
    34861 gaacttgcaa aagttaagcc aacatatgta atgcatttgc caaatacttc aaaaggagaa
    34921 tttgcctata aactttggaa agatgaaatg ataagattaa aagaagaggt tgagaaatct
    34981 ttaggtgtaa ctataactga agaagatata agaactgcta taaaagataa aaatgaagaa
    35041 agagaacttt taaaagagtt ttatgcactt ggtaaattac aaccatctgc acttacaggc
    35101 cttgagttac ataatgtttt atatcaagca ggttttaaat ttgaccgtgc agaacttaaa
    35161 cattctttaa gaaaagttat agatgatatg aaagaaagat atgaaaaagg tgaatgtcct
    35221 gttcaaaaag ataagccaag aatattgata acaggttctc ctattggtgg aataagcgaa
    35281 aaaatagtta aaactttaga agatgcaggg gcatcagtcg ttgcatatga actttgtgga
    35341 gctattagat caaacgattt attggttgat gaagaaatag aagatgtata tgatgcttta
    35401 acacaaaaat atataaatat aggttgttct tgtatgatga ataatgacaa tcgtattgaa
    35461 ttattagata gaataataga tgaatataat gtagatgctg taatagatgt agttttacaa
    35521 gcatgtcata catttaatat agaaagttat agaataagag aatttgttac aaaagaaaaa
    35581 aataagccat ttatgtctct tgaaactgat tattcaaaat cagatactga acaattaaga
    35641 actagatttg aagcgtttgt agagatgttg taggaataaa taaaagtagg aggaactatg
    35701 tttagtatag gagttgactc agggtcagtg gcaacaaagg gtgtgctatt tgatggtgaa
    35761 aaaattatta agaaaataat tataccaact ggatggagcc ctaaaagtac atctaaacag
    35821 gtctatgagt tgctaagtag tgaaattgac aaaaaagata taaaaaaggt ggtaggtaca
    35881 ggttatggaa ggggagtaat ggattttgct gataagaaag taacagaaat aacttgtcat
    35941 actagaggta tttacttttt aaacaagaac ataaggacta ttttagatgt aggtggtcaa
    36001 gatagtaaag ttataaattt agatagagat ggaaatgtat ttaactttat aatgaatgat
    36061 aagtgtgctg caggaactgg tcgattttta gagattactt ctaacctttt aggaagcgat
    36121 attgaaagta tagatacatt agctaaagga tatgaaccag ttaatatatc tagtatgtgt
    36181 acagtttttg ctgagtctga aattgtaagt cttctagctc aaaacatttc tactggagag
    36241 gtagcagcag ggatacttaa atctattgca aataaatcca cctcaatgtt agcaagaggt
    36301 gaggtaatag atgaagttgc atttactgga gggcttgcaa aaagtaaaga actagtaaaa
    36361 atgatagaag aaatactggg taaaaaaatt tttattgcag aagatactca aataatagga
    36421 gctttaggag ctgctgtaat aggatttaga taaaaacata taaaaggaaa atgagaagct
    36481 gaatttatta taaataaatt cagtttttta ttttatttta tttatttata aaggaaaact
    36541 ttggtataat tgatttaaat gattgtatat ttgtaaatac ttgatattta gtcatatata
    36601 acattataat tttaaaaatt agctcaaaat aagggggaga aagcgtgaaa aaatttactt
    36661 caaaaaaagt aacaaggttt gttgcgctgt ttttaatatc tattttagta atgtcaacaa
    36721 ttcctgtatc agctgacaat agcaatacat tgaatcagat aaaaaaagca gaatacagtg
    36781 agacgtataa acaatatcta aatgatgcta aaaatggacg tacagaaaaa tataatggga
    36841 ttataccaaa tccatatcag ttggaaggta ctcaaatcca aagtaaagga agaacagctc
    36901 caacatctta tgaccctaga aaattaggtc ttatgacatc aataaaaaat caagaggatt
    36961 taggaatctg ttgggatttt gctgcaatgg caaccttaga aagtttctta aagttaaata
    37021 attatggaga ctatgattta tcagaagaac acttaagatg gtgggcttca gatggtgaat
    37081 atggatggtc tgtaaatgat atgaatggtg ctttaaatta tgaagctatg ggatatttaa
    37141 catcttggtc aggtcctaaa ctagaaaaag atattccata caatggtaga gtatctaaag
    37201 cacaaggagc aaaaaaacca actaatatga atacagcacc tactgttttt aatgtgacag
    37261 atgctgtgtg tgtaagtaat gacataaatt ctacaaaaaa tgctatatta cagtatggag
    37321 cagtaacatc tggttattat gaagatatta aatatcaaag tgatgaccaa aattcatatt
    37381 attgtccaac aaaaagtttt aatacaaatc atgctatttc aattgtaggt tgggatgata
    37441 actattctaa agataatttt aatgcaaata ttagaccatc aaaaaatggt gcttggttaa
    37501 taaaaaatag ctggggagat tataattctg agggtggata tttctggata tcttatgaag
    37561 acaagacact tatgtctgat atagataatt tttcaatcaa aggtggtaaa aaaccaaatg
    37621 atgatgagaa gatgtatcaa catgactatg caagtattgt acctttaatt tcaaaaaaga
    37681 taacagctgc aaatgtattt gatttcaata gaggcgatga aactctaaaa tctgtaatgt
    37741 tcttaactga aagtatagga gctaagtatg aagtatatta tgctccagta gtaaatggta
    37801 tacctcaaga aaacaatatg aaaaaattaa aagaaggtac tgcccaatat tcaggataca
    37861 taacagttcc aattgattct tttgatatac cagaaggaaa gggtgcaatt gtagtcagta
    37921 tagaggggaa aaatggagag tcaactatag gttctgagtc aaatgtacca ggatatgata
    37981 catttaaagc aaaagctaat ttaggtgaaa gttatatcat agataatact ggaaaattct
    38041 ttgatataaa tagagatagt aacttctatc cgtgtaattt tactataaaa gctgttacag
    38101 aaaagtcttc tggtgagagt atcccaaatg agtctttaat tggtagtgat agatatgaaa
    38161 ctgctatcaa agttagtcaa aatggtttca attcttcaga aaatgtagtt ttagtaaatg
    38221 gcagttcaat agtagatgca ttggcagcaa ctccttttac atctgctata aattcaccaa
    38281 tattattgac acaaaaagaa gctttaaatt caaaaactaa agctgagata cagagattag
    38341 gtgctaagaa agtataccta ataggtggag aaaattctat aagtaaagaa attgaacaac
    38401 aattaaaaag cttaaatata tcgatagaga gaatatcagg aagtgataga tacaagacaa
    38461 gtttattatt agctcaaaag ttaaatggta taaaaaatgt atctcaaata gcagttgtaa
    38521 atggagtgaa aggattagct gatgcaatta gtgtaggcgc tgcagcagca gaaaataaca
    38581 taccaatcat acttgcaaat gaaaagagcg aattgcaagg agctgatgaa tttctaaatt
    38641 cattaaatat agagaaatct tatattattg gaggaacagc atccctatca aacaatctag
    38701 aaagtaagtt aaaaaatcca actagattat ctggtagtag tagagacgaa actaattcaa
    38761 agataataga taatttttat aaaaaagata ctttaaaaaa tgcatttgta gttaaaaatg
    38821 gaatcaagaa tcaaaatgat ttaatagatg gattggcagt tggtccttta ggagcaaaaa
    38881 ctgggtcacc agtaatttta gttggtgata aattagctga tagccaaaaa gaagttctta
    38941 aaaataagac tttagaaaaa gtaactcaag ttggtggagg agcaaataaa aatgcattta
    39001 aagagttagt aaaattaaaa agtgctaaat agagtactta agtattaaca tatattagtg
    39061 tgtattagta acttatctta ataaaagctg aaaataatta cttcaaatta ttgataaata
    39121 agataatcaa tgattgtaaa gttttgtttt cagctttaaa tttatgtagt ataagtttaa
    39181 aaacataaaa aagggttact ttatatagaa atatagaaaa tcttacattt tatatataaa
    39241 taacccatat ttaattaact ttttatagtg ttctaataga tattattgaa cttaatggta
    39301 aatataatgt gtaagtttca tttaaagttg gattagattc atctatatat cttgagcaaa
    39361 gtgtaattga taagctatct gcttctataa tttcaccata tagaggacaa ctgctaaagt
    39421 aagaatgtac ttcaacatat ttatttaagt tttcttgaac ataatcgtaa aaacggtttt
    39481 ttgtagtagt agccataaaa tcaactcctt tattttttat taaagttgaa acttttaaaa
    39541 agataaatat gattacttct attagaaact aagttaaaaa ataagcaaat agatatgaaa
    39601 attagaataa tatattattt atatcttaat tataacacta gataataaaa aatgctatat
    39661 aaaattcaga attttcgaaa gtttttaagc ttatttttaa atatactaat aatactattg
    39721 acattagata gaaaaagtat tatattgact atataaatta ttttagtcaa actggaggga
    39781 aaagatgcct aaatcgtatt ctgataaaga aagagagtat ataataaaaa gacttaaaga
    39841 agaagcaaga ttgtgtatgg agcaatatgg tattagaaaa actactgttg atgagcttgt
    39901 aaaacgggta aaaataccaa aaggaacttt ttatctattt tttcaatcaa aagaattgct
    39961 cttttttgag gtattaagag atatacatga ctctatacaa aaagaaatct tatatgagat
    40021 aaatagagta gatgaaagta ttacatgtga acaattgaca gatatattta tgaaattcta
    40081 taggatggtt gatagtactt caattttaaa tcttatgata aatggagaat ttgagatatt
    40141 ggtgagaaag ttaccagatt ctataattga agaacacttt agacatgatg actttgaaat
    40201 tggagagatt atatcttgca taccaaatgc aaaaaataaa gacatagaaa gctttagtgg
    40261 agcatttaga gcagtttttc ttaccatgct atataagcgc gaggttggaa gtaattgttt
    40321 tgaagatgct ttaagattaa tgataaacgg attagttata caacttatgg aatagaattt
    40381 aaattttgtt tgctaataac ttttattaaa aattattaac aaacaaaaaa attatatttt
    40441 attgaccata tagtcaaaat agtcaaaaat ttgaaagggt gatattgaat gattaaagtt
    40501 gatgatttat catttagtta tacagagaga gattttttac aaaatattaa ctttggagta
    40561 ggaaaagggg aaatactagg atttttagga ccatcaggtg caggaaaatc tacattacaa
    40621 aagattctaa ttggaatgat aactaattat ggaggaagtg tcattgtaaa tggagtagag
    40681 agtaaaagac actcaaataa attttatgaa aatataggag ttgattttga atttcctagt
    40741 ttatatgaaa agttgactgc aatagaaaat ttaaaatatt ttgggtctct atattctaaa
    40801 aaactactat ctattgatga gttattaaaa tcagtaggac tagaaaatga agcaaataaa
    40861 agggtatctg agtattcaaa aggtatgaaa tctcgattaa attttataaa agctttatta
    40921 cataatccag atattttatt tttagatgaa ccaacaagtg gtcttgaccc atcaaatagc
    40981 aaggttatga aagatataat tttatcagaa aaatctaaag gtaaaactat tattttaaca
    41041 actcataaca tgttagatgc aacagagctt tgtgacagag tagcgttcat tgtaaatggt
    41101 aaaatatctg ctttagatac accacataat cttattatgt caaaaggagc tattaaagtt
    41161 agatatactt actttgataa tggagaaaaa acttctgaat gttttctgaa caatactgct
    41221 aatgataaaa atttgaatat gcttattgag aaaaataaac ttttatcaat acatagtagt
    41281 gaaccaacat taaatgatat ttttattgag ataacaggga ggaatttaca atgaggctaa
    41341 aaaatcttat tttaggagat ataaagtttc aatttaagta tggtttttat tttttatatc
    41401 tttttttaag tattatatat atttgtatta tcaatgtatt tccaactttt atgagagaaa
    41461 aaatagctat aattatgatt tattctgacc cagcagcaat gggattgttt tttatgggag
    41521 ctattgtact tcttgagaaa agtcaaaggg ttttaaattc cttagctgta tctccagtaa
    41581 aagtatctga gtatatttta tcaaaggtaa tttcattagg agtaatatct agtattgtag
    41641 ctatgtttat tgctattaca ttaaatttag ataatattat aatatcaact ataggtacct
    41701 ttttttcttc tattatattt tctttgcttg gattgatact tgcaagtaaa gcatctagtt
    41761 tgaatcagtt tattgtttta agtattccta ttgagattat atgctttatt ccaccaatac
    41821 tcaatgtact tcttgacaca aaatcatatg caaatttgta cccttttaat atatgtattt
    41881 ctcttattag tggagataaa aattttataa tgattaatat tttaatttta atatcaatta
    41941 taataataat ttattttata acttattatt ttatttgtag cagttggaaa aaggtaggtg
    42001 gagtaaaact atgataaaga ttataaatgc gtttaaacaa gagtttgaac aaattaagag
    42061 agatgctatg ctttttatag tatgtgtttc tccaatatta tgtggagtat ttataaaatt
    42121 tggaatacca ttaatacaga atatatcact taacaagttt tattatcaat taaatttaga
    42181 gccgtatttc ttgatgtttg atttactttt agcttttatt acacctttta tgttcttttt
    42241 tgcttctaca atggtcatat tgggagaaat tgatgacagc atttcaagat atttaatagt
    42301 aactccgctt ggtaaaactg gttatcttat ttcacgattt ggaataccag gtatcttagc
    42361 atttattatt actatgattc tacttatctt tttttctcta actaaaattt ctttcttgtt
    42421 aaacttatca atttctttat tagttttatt acaaggaatt attatatcaa tattagtgat
    42481 ttctttatca tcaaataaac tagaaggaat ggtaattacg aaattctcag gtgtttttat
    42541 gatgggtatt ttagcaccat tttttatttt aaataaagca caatatattc tgttcttctt
    42601 accaactttt tggatatcga aggcatttaa ggaagataat tatgtctata tgtttatttc
    42661 aattgttata tcattaatat ggattttatt attatttaaa aagtttagta aaaaaatagt
    42721 taaataagaa aatttaatat ataaatgtaa ggttgacttg acagtaatgt tgaaaaatgt
    42781 tacatttaag atgtaaagtt aaccttacat gaatggagca aatatgaaaa ataaaataaa
    42841 gatattaaga gaaaaattag gattgacaca agaacaacta gggagattag ttggaacatc
    42901 tagacaggct ataaatgcta tagaaactgg taaaaatgaa ccttcaatat ggttggcata
    42961 tgatatttca agaattttta atgaaccaat tgaaagtgta tttttatttg aagaaagtga
    43021 aagaaaatca agagcacaga taagtagggg agaatattat ggctataaga aagataagaa
    43081 catttgatga tgaaatttta agaaaaaaga gtaagtatgt agaaaacgta gataataaga
    43141 taagagaaat attaaatgac atggcagaga ccatgtacaa tactccaaat ggaggaggat
    43201 tagctgcatg ccaagtagga gtattaaagc gattagttgt tatagattta ggagaaggac
    43261 ttattaagct tgttaatcct gaaattatta aacaagaagg ggaacaaatt gttgttgaag
    43321 gatgtttaag ttttcctgaa gtatggggta aattaaaaag accaaaaaaa gttacagtgc
    43381 aagctctaaa cgaatacggt gagaaaatag aaattaaagg ttcaggtttt atggcaaaat
    43441 gtctttgtca tgagatagac catttaaatg gtatagtttt tacagataaa attattgaac
    43501 atgtaaaatt gtaagataga ttggttattg aatttataaa atattttata gtaaggagtt
    43561 aaattatgag attatggcat aaggatttaa ttgatgtatt acctaaaaat caattagtaa
    43621 gtcaatggag agagctactt gctataaaag gttctataga taaaaaaggt actccaaacc
    43681 atctattagt gaataaagta ttgaattata gtatagatga atttaaattt tatacaaaaa
    43741 ttgtacatga tgaaatgtta aaaagaaatt ataaacctaa tgaacttaaa tatacaagta
    43801 tattaaaatg gaaaaataga aattttgcaa atgatatatc taatgaacat agtttaaatt
    43861 tagaaaattt atatgatgat tggcataata aaatgtattt aaagcaatgc ttatataatt
    43921 tagaagaaaa agcaacatgt ggaggaatac caataaatga atggaatata ttactttgta
    43981 aatatagtaa agattatgaa ttgtggtctg gaaatatcat gttttaatta ctatagatta
    44041 acattatagt attattgtat ataaagaggt gattatttgt ataataaaat aaaatatatt
    44101 ccaataaatt gtgaaatagc ttgtaataaa ttaaaaagga gtatgccata taaatgggat
    44161 ttaaatattt atcgtggatg tgagcatgga tgtaaatatt gttatgctat ttactctcat
    44221 aagtacatca actccaataa ttattttgaa gagatttatg taaaaacaaa tatagtagaa
    44281 aaacttgaga gacaacttaa aagcagtaaa tggaagaaag aagtaatcaa tataggagga
    44341 gttacagata gttatcaacc aatagaagct gactataaaa ttatgccaga aatattaaac
    44401 ctgctaataa aatacaagac accagctatt atttctacaa agtcagattt aattttaaga
    44461 gattacgatt taattgataa gctatctagg attacatata tcaatgtagc atctacaatt
    44521 accacagtaa atgaagatac acaaaggctt attgagccaa atggtgtgga ttcaatgaga
    44581 cgatttaaaa tgttaaaaga atttagaaaa actaacgcat cagttggtct acatattatg
    44641 ccaattatac catatattac agatgatttt gataatataa attcgctatt tagacatgca
    44701 aaagaatgta atgtacatta tgttttacct gggactttat acttaagggg tataactaga
    44761 ggtgtttttt ttgactttgt taaaaaagag tttcctgaat tatttgataa attatcaata
    44821 ctatatagtg aaggttcact taatagggag tataaaaatc aattgtataa aatggttaat
    44881 gaacttagat ataaatattc tctatcaagc agttactcta aaataatgaa ggaaaagtta
    44941 aaaaactcag gagatgtaca gatatctttt tttgattagt tttatataaa aaaatttttt
    45001 ttactatgat gattaaaat
//
LOCUS       DAEHWO010000028        42969 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEHWO010000028 DAEHWO010000000
VERSION     DAEHWO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42969
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.028"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            380..3928
                     /locus_tag="KNP54_001835"
     CDS             380..3928
                     /locus_tag="KNP54_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBF0892737.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            4113..6047
                     /locus_tag="KNP54_001836"
     CDS             4113..6047
                     /locus_tag="KNP54_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBF0892738.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6153..7148
                     /locus_tag="KNP54_001837"
     CDS             6153..7148
                     /locus_tag="KNP54_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0892739.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7120..7905
                     /locus_tag="KNP54_001838"
     CDS             7120..7905
                     /locus_tag="KNP54_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBF0892740.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7893..8591
                     /locus_tag="KNP54_001839"
     CDS             7893..8591
                     /locus_tag="KNP54_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892741.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8714..9187
                     /gene="ybaK"
                     /locus_tag="KNP54_001840"
     CDS             8714..9187
                     /gene="ybaK"
                     /locus_tag="KNP54_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBF0892742.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKFYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9384..10223
                     /locus_tag="KNP54_001841"
     CDS             9384..10223
                     /locus_tag="KNP54_001841"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBF0892743.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKN
                     VVI"
     gene            10236..10784
                     /locus_tag="KNP54_001842"
     CDS             10236..10784
                     /locus_tag="KNP54_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBF0892744.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10850..12031
                     /locus_tag="KNP54_001843"
     CDS             10850..12031
                     /locus_tag="KNP54_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBF0892745.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEIKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12326..12712
                     /locus_tag="KNP54_001844"
     CDS             12326..12712
                     /locus_tag="KNP54_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0892746.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEAFYEKNGCQRSLQSYIIKKKDSY"
     gene            12862..13125
                     /locus_tag="KNP54_001845"
     CDS             12862..13125
                     /locus_tag="KNP54_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBF0892747.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13254..14096)
                     /locus_tag="KNP54_001846"
     CDS             complement(13254..14096)
                     /locus_tag="KNP54_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBF0892748.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14391..15125
                     /locus_tag="KNP54_001847"
     CDS             14391..15125
                     /locus_tag="KNP54_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0892749.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            15135..16268
                     /gene="nagA"
                     /locus_tag="KNP54_001848"
     CDS             15135..16268
                     /gene="nagA"
                     /locus_tag="KNP54_001848"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBF0892750.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            16367..17116
                     /gene="nagB"
                     /locus_tag="KNP54_001849"
     CDS             16367..17116
                     /gene="nagB"
                     /locus_tag="KNP54_001849"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBF0892751.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17291..17563
                     /locus_tag="KNP54_001850"
     CDS             17291..17563
                     /locus_tag="KNP54_001850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892752.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18223..18927
                     /locus_tag="KNP54_001851"
     CDS             18223..18927
                     /locus_tag="KNP54_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892753.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18929..20416
                     /locus_tag="KNP54_001852"
     CDS             18929..20416
                     /locus_tag="KNP54_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0892754.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFVKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20621..22234
                     /locus_tag="KNP54_001853"
     CDS             20621..22234
                     /locus_tag="KNP54_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBF0892755.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22597..23427)
                     /locus_tag="KNP54_001854"
     CDS             complement(22597..23427)
                     /locus_tag="KNP54_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0892756.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKSACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23500..25227
                     /locus_tag="KNP54_001855"
     CDS             23500..25227
                     /locus_tag="KNP54_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892757.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FIYDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25264..27126
                     /locus_tag="KNP54_001856"
     CDS             25264..27126
                     /locus_tag="KNP54_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892758.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27459..28148
                     /locus_tag="KNP54_001857"
     CDS             27459..28148
                     /locus_tag="KNP54_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBF0892759.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28253..28939
                     /locus_tag="KNP54_001858"
     CDS             28253..28939
                     /locus_tag="KNP54_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBF0892760.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            28956..30863
                     /locus_tag="KNP54_001859"
     CDS             28956..30863
                     /locus_tag="KNP54_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBF0892761.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31316..32005
                     /locus_tag="KNP54_001860"
     CDS             31316..32005
                     /locus_tag="KNP54_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892762.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32441..32980
                     /locus_tag="KNP54_001861"
     CDS             32441..32980
                     /locus_tag="KNP54_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892763.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            32999..34042
                     /locus_tag="KNP54_001862"
     CDS             32999..34042
                     /locus_tag="KNP54_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892764.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            34044..34880
                     /locus_tag="KNP54_001863"
     CDS             34044..34880
                     /locus_tag="KNP54_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892765.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            34985..35659
                     /locus_tag="KNP54_001864"
     CDS             34985..35659
                     /locus_tag="KNP54_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892766.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35659..36711
                     /locus_tag="KNP54_001865"
     CDS             35659..36711
                     /locus_tag="KNP54_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0892767.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            36941..37789
                     /locus_tag="KNP54_001866"
     CDS             36941..37789
                     /locus_tag="KNP54_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0892768.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37779..39443
                     /locus_tag="KNP54_001867"
     CDS             37779..39443
                     /locus_tag="KNP54_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBF0892769.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYIGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            39492..40748
                     /locus_tag="KNP54_001868"
     CDS             39492..40748
                     /locus_tag="KNP54_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBF0892770.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            40771..42852
                     /locus_tag="KNP54_001869"
     CDS             40771..42852
                     /locus_tag="KNP54_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBF0892771.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIIVMIL
                     SMLYIKKYKRR"
BASE COUNT        17087 a         4353 c         7427 g        14102 t
ORIGIN      
        1 atgtatacaa aattaatttg ctaactgaat catataaaaa aaaacaaaat attttttaga
       61 gggaatgatt agatagaatt tttttgttat gaaattaatt gaagagtaat taattagaaa
      121 aggaatgaat aataatgaat atattacatt attacttttt gataaatcaa aaataaagtt
      181 ataattttta atattaatta agaatgatga aatatgaata aagattttac aaataaatct
      241 taagctatct tatttaattc taatacagga agaaggtaaa tgtatattga aaaaatcata
      301 gaaatagaag taaacaattt aaataaatac aaaggtttgc aaaagaagta atataattat
      361 atacaatgag gatgtgagta tgatgaacag actaaagcca agaattttag gtattagtat
      421 cttgtttatt attataatta ttttaacatg tggagctgtt ttcaagttta aatttaaatt
      481 agataataaa ttaaaagaaa ccacacatac atatttgtct gagtttacag aacacaatat
      541 aattaatctc aagacaagac ttagtggtca atttgacatg cttgaatcta ttgctaactt
      601 cataggaaac ttgaataata taaatgatga aatggtgatt gatttaatgg attctgatgt
      661 aaagcgaagt tctttaatta gaatgactat ctctacatta gatggggaat gttattctaa
      721 tgatggaatt acccataatg ttcaagatag agattatttt aaaaaagcta aaaatggaga
      781 aaagaatata tcagagcctt taaaatctat tgttaataat aaagaaataa tagttttatc
      841 taccccagtt tataaaagtg ggaaaatagt tggtgtttta agtggaattt atgattcaaa
      901 aaagttaaat gagttattag gattatctgc atttgatgaa aaagcagatg tttttgttgc
      961 aaagaaaaat ggagatatag ttgctcaaaa aacaaataaa aatagaaaga cgctatcatg
     1021 tatatttcag ctttttgaca aagataattg tgatgaagat gattgtctaa aaactataaa
     1081 agaaaatatg aaaaatgata agtctggata ttttaattat aacttagata atgaaaaatt
     1141 tatgttaaac tatcagccac ttggagttaa tgattggtat gttttttctg ttgtgccaaa
     1201 taaaatagta tctattcagt cagagaatat atcttatgat gtatatattt ttgcattaga
     1261 aatactacta gttatattga tttttataat atatatagca tgtattataa ataataacac
     1321 caaaattatt ataaatgaaa aagaaaaatt taaagtactc actgataata tattaggagg
     1381 ggttaaaacc tgtttaaaag atgaatatat gactatgaca tatgtaagtc aggggttttt
     1441 agagcttaca ggttactctt gtgaagattt aaataaaata tttaaaaata gatttaaaga
     1501 catgatttat aaagatgatt tagacaagtt taattgtatt attctaaatc aattagaaaa
     1561 acaagataaa attgaagttg aatatagaat tgtaagaaaa gatggaagta taatttggat
     1621 tttggagaga agtaagtcta taaatgataa taaaggaagt gagtgtattc agggagtttt
     1681 aactgatata acagaactta agaaaataca agaagaatta gattcaaaaa gatttgaaat
     1741 acaggctatc aatgatagta ttgttggtgg aatagtgata actgagataa atgatgattt
     1801 tgatagtata tatttaaatg aaggttattt aaatatgatt ggatatacac gcaaacaact
     1861 ggaagatgag ctaaataata aattaatcaa acttattttt aaagatgata gaacagaatt
     1921 aattaatagt ataaacaaac aactcaaatt aagtgataca tttgcatctg aacaaagagt
     1981 tgaaaaaagg gatggcacta ttatatggat tttattaaaa ggaagaaaga tgatttatga
     2041 taatggaaaa tctgtacttt gttgtgttat tgtagatatt acttctgcta aattattaga
     2101 gcaagaactt aaaaagagtg aagaacgtca tgaaatcatt ctaaagcaga cgcaaaatat
     2161 tataatagaa tgggatatag aaaaagataa aatgaatata tcacctaatt ggtataataa
     2221 gtttaaatat gaccctataa ctgaaaacgc aacaaaaaat ataattaaat cagtagatat
     2281 atatcatgat gatatggata agtttatttc attaattaaa cttacttcac aaggtagtga
     2341 gtatgaagag tgtgaaatta gacttagaac tagagatact atttacgctt ggtttagtat
     2401 aaaggcaaca actttatttg ataataatgg taaaccttat aaagtagtag gaagtttgac
     2461 tgatattgat gaatcaaaac gagaagctga aaagttgaaa gaaagggcag aaaaagaccc
     2521 tcttacagat ctgtataata aaaaagcatc acaatcactt atagaggagt acataacatt
     2581 ggataaaaaa agaaaaggtg ctttaatgat tattgatatt gatgacttta aaggaataaa
     2641 tgataattta ggacatttat atggggatgc tgtattaagt gaaattgcaa atgacctaat
     2701 aaatctattt agagcaaccg atatagtagg cagaattggt ggagatgagt ttattgtatt
     2761 tataaaagat atttctgaaa caagagatat tataaataaa gcagaagaat tggtaaaaac
     2821 atttgaaagg tcttttttag gtaaaggacg aaattataaa atatcattaa gtgtaggaat
     2881 tgctaagttt ccacaagatg gtatggacta tatgacacta tttagaaatg cggatatagc
     2941 tctttactca gccaaaggga agggcaagaa ttgttataca ttgtatgata aaaaatttga
     3001 taaagtccaa tatataacta atacaagaaa tgcaggagat agtgataatg tagagatgtc
     3061 ttttaaagaa catatcacaa attatatatt tgatatacta tatgaatcaa gtgatataga
     3121 agtggcagta aatttaattc taagtattgt aggtaaacac tttaatgtga gtcgcatgta
     3181 tatatttgaa aattcagatg ataatcgagt atgtaaaaat acatttgaat ggtgtaacga
     3241 aggtgtaacc tcggaaatta ataatcttaa aaatatttgt tacaaggatt taggcaacta
     3301 tcttttaaat tttaatgcag atgggttatt ttattgtaat gatattgaaa atttaggtag
     3361 tgatgtgaaa aaagtactta agccacaagg catacgttca atattacaat gtaaaatttt
     3421 agagggtaat gaatttagag ggttcatagg atttgatgaa tgttcatata atcgtatgtg
     3481 gactaatgat gaagtgaaca ctttgacatt tatatctaaa acgctcagta tgtttttatt
     3541 aaaaatgcgt attcagagta agctagaaga gtctttaaca attcaaaaat ctgtgatgga
     3601 taatatggat atatgggcat atgttgttga caggaatacc tatgaattac tatttatcaa
     3661 taaaaaaatg cttgagtcag caccaaacac tcatgtaggt gatttatgtt ataaagcgat
     3721 atggaataat caagataaac cttgtaaaaa atgccctatg atatatttaa aagatggtga
     3781 tgatacttat aaatcattca tgcataataa aaagtttgag gtacaggcaa atataactac
     3841 aactactttg aaatggtttg atggtaaaga tgcatgttta atatttggaa gtgaaataac
     3901 tagtattgaa gctgaagaaa atacttaaaa tactgtgtta tatatatact taaaatcgca
     3961 atttgaattt attagactta aaatgtctat ataaatcatt taagttgtgg ttttaagtat
     4021 tttttatgat ataattaagc gttaagaaca aaattaaaag atacttttgt ataaaaaaat
     4081 atttgttaaa tatatattga gcaggtgata atatggaaaa taagttttta ccaataagca
     4141 aacaagatat gatagataga ggatgggaag aattagattt tgttctagtt acaggagatg
     4201 cttatgtgga ccatcatagt tttggaacag caataatatc tagagtttta gaaagtgctg
     4261 ggtataaagt tggaataata gctcaaccag actggagaac tacagatgat tttatgaagc
     4321 taggaaaacc tagacttgca tttctagtta atgcaggaaa tatggattca atggtcaatc
     4381 attattctgt aagtaaaaag catagagaaa aggatatgta ttctccaggt gggaaaatgg
     4441 gttatagacc agatagagct actatagtat attgcaataa aataagagaa gcatacagtg
     4501 atgttgcaat agtaataggt ggaattgaag cgagcttaag aagatttgca cactatgatt
     4561 attggagtga taaggttaga aagtctatgt taatagatag tggagcagat ttattagttt
     4621 atggtatgag tgaaaagcag attgtagaag tagccaatgc acttaatgat ggatatgacc
     4681 caaaatacat tagacatatt gatgggacat gctatatttc agatacattg gaagaaatat
     4741 atgataaata tatattaatt ccatcatata aagaaatttg tgaagataaa atgaagtatg
     4801 tagaagcttt taaaattcaa tatgatgagc aagacccatt tagaggtaat ataattgttc
     4861 aacctcatgg aagtaagtat ctggttcaaa ataagccaga aaaaccactt agtagagaag
     4921 aattagatga agtatatgga ttaccatatc agaagacata ccatcctgta tatgaaaaat
     4981 ttggaggaat accagctata gaagaagtaa aatttagtat agtaagttca agaggctgtt
     5041 ttggtagttg ttcattttgt gcaataacat ttcatcaagg tagagcagtg caaagtagaa
     5101 gtgaaaaatc aattattgat gaagcaatag gaataacaaa tttagatgat tttaaagggt
     5161 atatacatga tgttggaggt ccaacagcta attttagaag accagcatgt aaaaaacaaa
     5221 ttactaaagg tgcttgtaaa aatagacaat gcttatctcc atcaccatgt aaaaatttag
     5281 atgcagacca cagtgaatac ttacatttac ttagagctgt aagaaaatta cctaaaataa
     5341 aaaaggtgtt tgtgcgttct ggaattagat acgattatgt aatggcagat aagaacaata
     5401 aatttcttag agagttgata gagcatcatg taagtggtca gttaaaggta gccccagaac
     5461 atatatcaga agaagtttta aagtatatgc aaaaaccagc aggaaaaact tatgataaat
     5521 ttagacagaa gttttttgct ataaatgaag aattaggtaa aaagcaatat ttgataccct
     5581 atttaatgtc tagtcaccct ggttctacct taaatagcgc tatagagtta gcagagtatt
     5641 taagagatac tcactaccaa ccagagcagg ttcaggattt ttatccaact ccagggactc
     5701 tatctacaac catgttttat acaggtattg acccgcttac aatgaagcca gtttatgttc
     5761 ctaaatcaaa acgtgacaag gcaatgcaaa gggctttatt acaatataga gcacctagaa
     5821 attatgattt ggtatactct gcgttagttg aagcaggaag agaagactta attggttttg
     5881 gacatagatg tcttataaag ccaaaaaatg aaaagcctta ttttaataga aataattcta
     5941 aaaaaaatgt atctaaagga acaaataaaa acaaaaaaac taatacaaat aacagaagta
     6001 ataaaaatca acaaaaaagt tcaactaaaa aaaagaaaaa acattaaagt ataaataaaa
     6061 atacttaaaa aagaaggatt attcgataaa ttaacagaaa ttagtataaa taaatataat
     6121 tattttaatg acgttacctt tgggaggaag agatgaaaaa gtatatttct ataatattat
     6181 tagtggtgtt gactatggtt gttttggtag gatgttcacc aggaaaagat aaccctaaaa
     6241 ataaggagct atcagttgtc aaacaagtaa aagtagctgt tccagatgga ctaccagcag
     6301 tggcaatagc taaacttgca aatgaaaatc cagagattaa agaaggatat gaaacagtgt
     6361 atagcattga aaagacacct gaagcgattt ccactagagt gatgaaaaaa gatgcagata
     6421 tagctatagt tccttcaaac atggctgcaa tagcgtataa taaaacttca tcatataata
     6481 ttgttggaac tgtaggaatg ggttcacttt atttggtgtc aacagaaaat ataaaagatt
     6541 actctgattt agttggtaaa gaagttggat gtactggaaa aggacttact ccagacataa
     6601 ctataaaaag tcttttgtta caaaaggata taaattattc agatataaaa tttaattatg
     6661 taaattcagc aagtgaactg gtaccattat tggctactgg taaagttaaa acaggtattg
     6721 ttccagaacc tgcacttagt gctttgatgt ctaaaaatcc agacataaaa attataaaaa
     6781 gtttaaatga ctcatggaag gaagtaagtg gttcaaaaga tggttatcct caatctactt
     6841 taattgtaaa gtctgaattt ttaagagata ataaagattt tgttgattct tttgtaggtc
     6901 aattatcaaa tagtatagat tgggcaaaca aaaatcctga agaattaggt gcatattctg
     6961 aaaaaataaa aatatctact gaatcaaaga taataggaaa atctcttgaa agagctaatt
     7021 tgaaatatat tccagttaag gacatgatta aagattataa aaattactat gagaaattag
     7081 ctaattttga tgataagaca ttaggaggca aagtaccaga tgaagcaata tactttgttg
     7141 agaaataaaa aaaataaaga acaatttata gataaaatgg aggtaacact ttcttgtgtt
     7201 atcctcttat ttttatggca aattattgct ttaaaaattg ataatgatat ttttttacca
     7261 acagtaggtc aagtgtttaa tagtataaaa gagattatgc taaattctag tttctatata
     7321 gatatacttt actctatggg gagatgtttt tttagttttt tactggctat gatttttgct
     7381 attatacttt caatagtgtc ttatttaaat agatttttta gaaacttatt aaagccaatc
     7441 aatgctttga cacgttcaat accaactatg atattggtag tacttgcact tatttggttt
     7501 gaaaaggata gtaccccttt tatagttgga tttactatag tttttcctat attgtatgat
     7561 aacgttttgg gcgctatatt gaatatagac aagaacttat tagaaatggc taatgtgtat
     7621 aaaataaggt ttatagataa ggtgttaaaa atttatttac cagccataaa atttcaaatt
     7681 atatctatac tagtatcaac attttcttta agtttgaaag ttgctatagc aggagaggtg
     7741 tatagtcaac ctacatatgg tattggaact atgatacaga ctgaaaaaat taactttaac
     7801 acatctggaa tatttgcatg gataattatt gttcttttaa tatctgctat tttacaaata
     7861 gctcaaaagt ttttagcaag gagagctttt ttatggaaaa gataaagttg agtattgaaa
     7921 atataaataa aagatatgat agtcgtatta tatttagaga ttttaatatt gatttttatg
     7981 taaatgaggt aaattgtatc cttggaaaat ctggttgtgg aaaaactaca ctcttgaaca
     8041 taataagtgg gattattaaa aatgacacca acaatctaaa tatcaaagaa aatttaaata
     8101 gagtaggaaa taagcttgaa gctagttaca tatttcaaga tgatagactt atagactggt
     8161 taacagtaga agaaaatata aagatagttg taaataaata ctataataaa actcaattaa
     8221 ataaaatttg tgatgaatac ttggaattgg ttggaattag tgattataaa aaattctatc
     8281 ctcaaatgct tagtggaggt attagacaaa gagtaaatat tgctagagct tttatatatc
     8341 catcaaaaaa cattataatg gatgaacctt ttaaatctat tgatgcaaag aatacacagc
     8401 ttataatgga taattttaga aatatattaa gaaaagaaaa gagaactgtg ttatttgtaa
     8461 ctcataatat tgaggaagca ttgtttttag cagataggat atttatttta ggagactctc
     8521 caattagaat aaaaaaaata ttaaaaaatt ctaaggaatt ggaaaaaaat gaagttttga
     8581 agttgatata gagttataat aatactgtcg ttttaaaata tatttggtta aaatctataa
     8641 gactatatta aaatagtaca gaatattcaa aactgtgtat aatgttcgta ttttataaaa
     8701 aggaagtgaa tgtatggtta agactaatgc tatgagaata ttagattcaa ataagattga
     8761 ttataaagta atgtcttatg aagtgaaaag tgaacatgtg gatggtgttg aggtggcaca
     8821 tgatatagga agagatgtaa atgaagtgta taagacatta gtaactcaag gagttagtaa
     8881 gaatatatat gtatatgtaa taccagtaca tgaaaactta gacttaaaaa aggctgcaaa
     8941 agtagctaaa gagaaaagtg tagagatgat tcatgtaaaa gatataaata agcttacagg
     9001 ttatattaga ggcggatgtt ctcctatagg tatgaaaaag ttttataaaa cttttgtaaa
     9061 tgaaagtgca aagaatttag atacaattat tgtgagtgca ggaaaaatag gatatcaaat
     9121 agaactatct ccatttgatt tacaaagact tataaaagta gaatttgtag atgtaataaa
     9181 aaaataagaa ttacatataa aatatagagc ttatattctc aataataggt gttgtaatat
     9241 taataaaatg aataagaatt ttaaaataaa tattcagtta cttatgtgta attggtataa
     9301 aaatattgag aaattttaaa aacaatggta aagtgtaagt ataatcacga atatttttta
     9361 taaagtaatg gagggatgtt cgcttgagaa aaataaaatc tgaacaaatc gtcgagcagg
     9421 taaaaaaact ttgtatagaa gcgagcctat atttaggaga agatgtttta agttgtataa
     9481 aagaaaaagc gaaaagcgaa aagagtgaag ttggaaaaaa tatattgaat atattagttg
     9541 aaaatgctga aatagctaaa gaaaaaaata taccaatatg ccaagatact ggtatggctg
     9601 tattttttgt tgaaatagga caagaagttt taattgaagg agacacactt actgatgcta
     9661 taaatgaggg agtaagacaa gggtatgaag aaggctactt aagaaaatct gttgtaagtc
     9721 caattaacag agtaaataca aaagataata cacctgctgt tattcattat gatatggtaa
     9781 aaggtgataa aattaaaata gaatttgcag ctaagggatt tggaagcgaa aatatgagta
     9841 agatgaaaat gttaaagcca tcagatggat tggaaggaat taaaaaattc ataatagata
     9901 cagtttcaga agctggacct aacccatgcc ctcctatggt aattggagtt ggtataggtg
     9961 ggactgtgga caaatgtgct caaatagcta aaaaggcact ttttagagaa ctaggtgaat
    10021 ttaataagga cgaaaatata gcaaaacttg aaagtgaact attaacagct attaataaac
    10081 ttggtatagg acctcaaggc ttaggtggta ctacaacagc tttgggatta aacatagaga
    10141 cttttcctac acacatagca ggtctacctg ttgttgtaaa tataaactgc catgcatcaa
    10201 gacataagaa tgtagtaatt taggaggaaa ataaaatgat aaaaataact acacctgtaa
    10261 atgaaattga tatagcaaaa ttaaattgtg gagatacaat tagtttgagt ggtatacttt
    10321 atacagcaag agatgctgct cataaaagat tgatagattg tataaataaa ggtgaagaat
    10381 taccatttga cgtatatggt caaggaatat attatgtagg acctactcct acaaagccag
    10441 gagaagttat aggtgctgca ggtccaacga cgagttatag aatggatgat ttgactatac
    10501 ctcttttaga aagaggtctt agattgatga taggcaaggg aaaaagaagt gatgaagtta
    10561 tagaaggtat gcaaaaatac ggagcagttt atcttgctgc aataggagga gctggagcgt
    10621 atatttcaaa ttcaataaaa tcatgtgaaa ttattgcata tgaagattta ggagctgaag
    10681 ctataagaaa gattgtagta gaagacctta agcttacagt agcaatagat agctatggaa
    10741 ataatatata tgagcaaggt cgagcaattt atgaatgtaa ataatgttta gaaataaata
    10801 tgaatatcaa aattaaaaat agttgtgtat attttaagga ggaaaattga tgtctaagga
    10861 ttatgcaaaa ttggcattag aaatgcatga aatcaacaaa gggaaagtaa gtgtagaaag
    10921 caaggtagaa attaaaacta aggatgattt atcaacagca tatacaccag gggttgctga
    10981 accttgttta aaaatacatg aaaatcaaga tgatgtttat agatacactt ctaaagggaa
    11041 tctagtagca gtagttagtg atggaagtgc tgtacttgga ttaggtaaca ttggtgctga
    11101 agcatctata cctgttatgg aaggtaaagc tatattattt aaacaatttg cagatgtaga
    11161 cgcttttcca atatgtttaa agactaatga tgtagatgag atagttaaat ctgtagagtt
    11221 gatggagcct gtatttggag gtataaattt ggaagacata tcttctccaa gatgttttga
    11281 gatagaagag agattaaaaa aatctttaag tatacctgtt tttcatgatg accaacatgg
    11341 gacagcaata atagttgcag ccgccataat aaactcaata aagttaattg aaaataaaaa
    11401 aatagaagat ttagaaatag ttataaacgg agcaggagct gctggtatag ccatagcaaa
    11461 gatactactt aatatgaatg ttaaaaatat aatcttatgt gatagaagtg gagcattgga
    11521 agctagtata gaaaatctaa actatgttca aaaagaaatg ttaaaagtaa caaatataag
    11581 aaatgaaaaa ggacctttaa aagatattat aaaaggaaaa gatgtattta ttggtgtttc
    11641 aggtccagga gctgttacaa aggaaatggt tgaaagtatg tctgagaagc caataatatt
    11701 ggcaatggca aatcctactc cagagataat gccagaagaa gcaaaattag gtggagcatt
    11761 tataatggga acaggtcgtt cagacttccc taatcaagtc aataatgtac tggcttttcc
    11821 tggaatattt agaggtgcac ttgatgttaa ggctaaagag ataaatgaag aaatgaagat
    11881 agctgctgca tatgcaattg ctaatacaat aagtgatgaa gaaatatgcc cagagtatat
    11941 attaccagat gtatttaata agaatgtagt aaaaaatgtt gctaaggcag ttaaagaagc
    12001 agcgataaaa actaaagtaa atagaatata aatttttata tgttcatata tccttatatt
    12061 atcgggtata tgggcatttt tattataggt ttatactcat atatccttac ttttatatac
    12121 atatctttat gattaaaggt gttagaaaat gtagtaaatt ttatactatc agactctatc
    12181 tttattactt tagtagatac atggttgtaa aggtttatag aaaaaaatat aggaaggcag
    12241 atttttattg ttgcgtatat atgagaatga tataatatga atattataaa ttaataaatt
    12301 taaatttatg gaggtacaag agatgatgga atataaagtt aatgaccaag aacttaatgc
    12361 ttcaatgttt atcccattcg tcaacaggat atggccagga gattatgata tggataaaac
    12421 acagactgca ttatcaaaaa ctttgaatat aactgcttat gatgataaag tgcttgtagg
    12481 atgtctgcga gttctttcag atggttatta ttttggaaca attacagaat tgcttgttct
    12541 tccagagtat cagaaacaag gcattggtag taagcttttc cagcttgcta aagagaacac
    12601 cccaactatg ctatattttg gtgcacagcc aggagtagaa gcgttctatg aaaaaaatgg
    12661 gtgccaaaga agtctgcaat cctacataat aaaaaagaaa gatagttatt aaagttccag
    12721 ctttcaataa tcttaaaagt acaatatttt agtggaatca tttcattttt tattactaat
    12781 atgacataaa catgtcatat tagtattgat atacttttaa tatggttaag agccaaagaa
    12841 aaatataagg agtgatttaa aatggaagaa actaaatttt gccaatgctg tgcaatgcca
    12901 atgggacaaa ctgatgaatt atatgggaca aataaagatg gaagtaaaag tactgattat
    12961 tgtagttatt gttttaaaga tggtgagttt acagctgata taagtatgga agagatgata
    13021 gaagtttgta tccctcatat gcttcaaagt aataaggata tgactgaaga tgaagcaaga
    13081 acaatgatga acaatttctt tccaacatta aaacgctgga aataatttta tgcaaaatta
    13141 gttatatgca aaacatgaaa tatggtgttg agaataaggg gtggtgtgct ttatagcata
    13201 ccacctgttt tgttacttgg agttcagtta ttttcctaaa tattttaaat atactatttt
    13261 agataagttc cctcttcatc ttgataaatt aatccttttt tcataagcac tccaagagct
    13321 cgtttaaaat ttttcttact tgaattaaat aatatagaaa tatctttagg gtcagattta
    13381 tcattaaatc tcatatatcc atcagaacct tctaaataac ttaaaatctt attttctaaa
    13441 gtatcaagtt catcctttct atttcctcta ggagaaagac caagttttcc atcttcatat
    13501 atttttatga catgtaaatt ttcaagaaca tcaccagttt ttagttcagt aaagtactca
    13561 ttatgaagta ttacaccagc atatttattg tctacacata tcattgcaga attattagtt
    13621 tggaatccat atacaactcc agttacaata tctcctacat tgtaagtatg gtctgttaat
    13681 aagtatgaat ctatgtctgt agtagcagca attcttttgc ttttgtctaa atatatataa
    13741 aataaatatt tttcgtctct aaatagtgga taagtcttag ctttaaaagg aactaatatg
    13801 tctttaggaa gtcccatatc tataaaagta ccaatgtctg tattatcaac tacttttaaa
    13861 tgtgctacat ccccaacctt agctaaaggc ggtattaaag ttgcagcagt tctgtcatca
    13921 gaatctttaa atatgaaagc atttacttca tcacctatgt ttatttcatt ttttccgatt
    13981 aatctattat gaagaagtat atcgtctttt gtgttattag tttgtccatc caaaaaatat
    14041 ccaaattcag tttttctttt tactgtaagt ttattaaaat cacctatgtt tatcaaatta
    14101 aaatcatcct ctcattttat atttataatt tagccataat atacttatgt agtagtttgt
    14161 cacagtatcc atattagtat tagtgaaatt tacaataaat aatatagtta tttatgtatt
    14221 tttcaattct ctagcttctt atatagtata aactccaatt tcttttttgt ctttaggttt
    14281 tattaaaatt tttacaaaat aagttaaaaa gtattgaaat aaaatttctt ttaaagtata
    14341 attggtatat accaaaattg gtatatacca tatcgaaaag tggtgactat atgaaaatag
    14401 taaataaatc tagtaatata ccattgcata ctcaattaag ttcaataata agagagatga
    14461 tagaaactgg tgagcttaaa gagggcgatg caataatgcc agaaagagaa ctttgcaaca
    14521 tacaaaatgt aagtcgtatg acagtaaata aaaccattgt tggattagtt acagaaggac
    14581 ttctttatag ggtacaaggt aaagggacat tcgttgcaaa gcaaaaaaag aagtatcagt
    14641 tttcaaatgt aaaaggtttt actgatgtta tgaaagaaaa gggagtaaac ataaaaacgg
    14701 atatattatc ctttgagatg gaactaccag atgatttagt taaaagaaag cttggaataa
    14761 gtgataatac tacaaatata tataagattg tcagacttag atatactgat ggagagccat
    14821 ttggattaga aatagtatat ctatcagaag aaatgtgtaa gggtctaaca aaagggatat
    14881 tggataattc ttcattatat agggttttaa atgaaaaata tggctataag atacaaaaag
    14941 ctgaacaggt aatggagcca gtaatacttt cagatgaaga aagtaagctt cttgaaacag
    15001 atgaaggtgc tttagctctt aaacttcata gaaattccta taatagagaa ggtagcccta
    15061 tagaatatac catatcaata tttagaacag ataaatatca atatgaaata gtattgagtg
    15121 agtaggtgaa taatatgaaa tgtttaatta atggaaagat aatattaaaa aatcaaatct
    15181 tagaaaataa agtattagta tttgatgaaa aaataattga tatagctgat agtgtaccaa
    15241 aagattgtga agttatagat gctgatggaa aatatatatc tccagggctt attgatattc
    15301 atatacatgg aaacatggga aaagatacaa tggattcgac tgatgaatct attgaaacaa
    15361 tttcaaagtc aattatgaga catggagtaa catcttttct tccaactaca atgactatgg
    15421 ataaagaaca tgtttatgat gcacttgaag ttattaaaaa agcccaaaat agaaagcttg
    15481 aaggggcaca agtattagga gcacatttag aaggaccttt tataaatgag aattataagg
    15541 gagcacaaaa tgaaaaattt ataataaatt caaaatacga atttataaaa gaatataaag
    15601 atgttataaa agttataact tatgctccag aaaaagatat tgattttgat tttactagag
    15661 aaataaaaag atgtacagat atagttttat ctattggtca tagtaatgca aattatgacc
    15721 aagctaaaga agctataaat ttaggagtaa ctaatgtaac tcacatgttc aatgcaatga
    15781 ctggtttaaa ccatagagac ccaggcgttg ttggtgcagc acttacaact aatgtgtaca
    15841 gtgagttaat agcagataca atccatataa ataaagattt atttcaattt atactaaata
    15901 ataaaggaaa agaaagactg attttaataa cagattctat agaagctggt ggtcttgaag
    15961 atggcaatta ttctcttgga ggtcagaaag tcatagttaa gggtaatgaa gctagacttg
    16021 aaaatggagc attagctgga agtgtgttgt ctttaaataa aatggtattt aacttcttag
    16081 ataatacaaa ccttaaagtg aatgaagcaa ttaatttagc ttctttaaat ccagcaacat
    16141 ctttgggaat aaatgacaaa aaaggaagct tagaaatagg taaggatgca gatatagctg
    16201 tatttgatga gaatttagat tgtaaaatga cactttgctt gggggacgta gtatataaaa
    16261 atatatagta tacaaaacaa accttaaaga cagtaaaaac aatataaaaa ataataaatt
    16321 aaacttacat tagtaaaagt agtagttaaa atttaggagg aataagatga gagtattagt
    16381 gtgtaaagat tatgatggaa tgagtaaaaa agccgctgaa atgatagcag ctcaaatagt
    16441 tttaaaacca aattcaatac tgggactagc tacaggaagt acaccagtag gtatgtatag
    16501 agatttagta aaaaaataca atgataatat agtagatttt tcagatgtga tgagctttaa
    16561 tttagatgaa tattataagt taccaatatc taatgaccaa agctatgatt attttatgaa
    16621 agaaaatcta tttaatcatg taaacataaa gccagaaaat actcatctac caaatggaat
    16681 ggctgatgat attgaaaaag agtgtatgaa ctatgaagct tctatagatg cagctggtgg
    16741 tatagatgta caagtacttg gaataggtcg taatgctcat ataggtttta atgaacctga
    16801 tactaaattt gcaaagagaa ctcatgtagt tgaacttaca gagtctacaa tagaagctaa
    16861 tgcaagattc tttaaatcaa gagaagatgt tcctaaaaaa gctgtaagta tgggaatagg
    16921 ttcaatattg aagtctaaga aaatattgct tttagcttca ggagaagaaa aagctgatgc
    16981 agtatataat actgtttatg gagatataac tccagaagtt cctggttcta tacttcaact
    17041 tcataaagac actatagtta tagtagatga agcagcagca agtaaattga atccaaaaga
    17101 ttataaatta gtataagaat agaatgtagt ttaagtaaaa aatagctatc attgagtaat
    17161 caaatttatt taatgatagc tatttttatt taaatttttt acttcttttt atttaaatta
    17221 gttattattg tttaaattac ttgcttatta ctttttacga aaactcgtta tcaagaagta
    17281 tccaaataag atgttaaaaa ttattatgtt tagtgggatt ctatcaagca taataaaatt
    17341 acctataatt gggatattac caactggaaa cataaagaag aatacaggca tcagtgatag
    17401 taaaaaagat ggaaaacaaa gaagaagtaa tcttggaata tcaatatacc aactaccatc
    17461 ctttttgtat tctctaatca ataattcagt tcctagtaat aaaccaatac caccagagga
    17521 aattaaatta ataaaaatgt atcttttaaa gtcttgcata taaccagtgt aaaattgagt
    17581 atagaaatca taatttaatt taacagctaa aaaatacata agcaatagaa tgattaaaaa
    17641 taaaagatat ctaagagctt ttttcatttt aaattctccc ttcagaaata ctttattcag
    17701 ttttattttg ttggaatctg attttatcat ttagtttaag aaatccataa tattagtgaa
    17761 gaatgaaata agtattatat atgaataaat atttttagaa ttaaggtgaa ttgtagtgct
    17821 taatataact ataatattaa ttgtttgaat attcaataaa aagtttgaaa aatatcaatt
    17881 ttgatataaa ctgaataaat acagttgaat attaaattat tattttatca aaaatatgca
    17941 aagtactaca ccttcaaata tcacctaaag taattaaaag gcaattaagg tgaagtagtt
    18001 caagtatttc taaaataagt ttaataaatt ctataataat ttattttttg ccttaaaatt
    18061 gccttaaaat ccaaacaatt ttaaaactaa tgtactataa aaagctggta taatttaaat
    18121 atagtaaaaa ataagattta tcttatctat tgggatttaa ttatttaatc aatatattta
    18181 taccatttaa tttaaataaa aagtctatta aggagtgagc ttatgagtaa gttaatttat
    18241 atagcagatg atgaagataa tataagaaat ttggtaaaga cattcttaaa aaatgaaggt
    18301 catgatgtta tggattttaa aacgggtgat gaacttttag aacaatttaa tataaaggag
    18361 tgtgacttag taatactaga tataatgatg cctggctcaa gtggttttga agtatgtaca
    18421 aaacttcgtg agaaaagtac agtcccaata atcatgctta ctgcaagaga tacagatata
    18481 gattatatta cagggataac cttaggtagt gatgattatt ttacaaaacc atttagccca
    18541 atgtctttgg ttatgagagt aaaatctata tttagaagga tagagtttga aaagaaacaa
    18601 aattatgata aatatagtaa ctcgatagat atggaattaa aatttggtga tgtaataata
    18661 aataaaaaga ataaaatcgt tacaagtaaa aatgtaaata tagaccttac accaaatgaa
    18721 tataacctat tgacttattt gtttgaaaat atagatagag cagtttccag agatgaatta
    18781 ttaaacaaaa tatggggata cgatatagaa gttgagacaa gggctgctga tgatacagtg
    18841 aagagattac gtaaaaaaat tttaaataca aatattttaa tagaaactgt atgggggttt
    18901 ggatttaggt tgaaggagaa aagttaagat gaagaatgga aatgacaaga atagaattgg
    18961 aaagattaaa tccaaattta aattaaagtt ctcaaagaaa aatataagca taaaaactag
    19021 gattttgttg agtatacttt gtttgataat tatagtattt atgataatat tagtatcttt
    19081 taatgtattt cttgatacat atataaaaac aactgcgaat gaagaattga caaagtctac
    19141 agaaatagta gaacatatgg atagtaattt tagacctatt aagccaccac aagatgatgg
    19201 aaagcttcct cccaaagtat tatctaattt tatgagaaat gtacaagata aagttaggat
    19261 ggcagaaaca caatcagatg ctgatgctat ggtagttgat tctaagtata acctgatatt
    19321 tccaacaaga gaggatgatt tcttaaaaaa tgttgatgag atggagctga ttagggagtg
    19381 tattcaaaat gaaaaattag atttaaattc agatgaaaat acacggatat ctaccagaaa
    19441 taaggattat tatatttcaa ctgtaaaaat tactagtata tatggtgaac aagacaagta
    19501 tcttatactt tttatagaca tatcaaaaac tctaaatcta gcacaaaaga taaatattgt
    19561 attaatatct gtaatgtgtt ttgctggaat attagcaata tttacagctg tgattttatc
    19621 tgagaaaatt gctaaaccga taaaagagtt gtgtgagttt gtaaaaaaaa tgggtcaagg
    19681 agatttcaaa agaacctact ttgacttttc agataaagaa ttagtagagc tctcaactgt
    19741 tatgaataag agtgctgagt atctggataa gtatgataat gaacaaaaaa tattttttca
    19801 aaatgcatct catgaattaa ggacaccact tatgtctatt aaaggttatg cagaagctat
    19861 aaaatataat gttatagata gtaaacatgc aagtgatata attcttgaag aaagtgatag
    19921 gttaagtgat atggttgaag atttattata catttctaaa atagataata taactaaaga
    19981 ttttgaactt gtagaatgtg atttaagaga agtactttca aattgtggag ctaggcaaaa
    20041 tgtaagagct ataaataagg ggataaaatt tatttatgaa tttgatgaag aaatggtttt
    20101 atttgaatgt gatgaaaaaa acatttccaa agcatttatg aatcttatag aaaatgcttt
    20161 gagatacgct aagagtgaaa taaaaatagt gtgtaagtat aatcaaaaaa atatagttgt
    20221 gataatagaa gatgatggaa ttggaatcaa gaaagaagat ttacctcatg tttttgaaag
    20281 attctataag ggagtagggg gaaatcatgg aattggatta tcaatagtta aatctattgt
    20341 aaataagcat ggtgggcgta tatacgtaga aaatggcaaa aaaggagcta aatttactat
    20401 attatttaaa ttgtaaaaaa attagagaaa atatagagat gtttgaagtt gttttttata
    20461 tatatctgtt gtatactgtt gaaaaaagaa caatattaag ctgacatata ttacgatagt
    20521 tgacatttaa agtaaatgct taaatataga tacgaaagga aaagtaaaat ctgaagtgta
    20581 tttaggttta agtaagcttc ttattttata aaaaatatgt atgaaagaac agctgatttt
    20641 taatattaca aatttagtaa cggttgtatt tgaagctttt gtcatccata tgtttttatc
    20701 agacttttta ggtcagaaag aagggtatat aaaagttgta agatatgcta aactgggttt
    20761 tataatatgt ttaggattct gtaatttaat aactttaaac cctaaaatca caatgccttt
    20821 aattttcatc cttatttttt caacatcatt tttatataaa ggaaatttaa agacacgatt
    20881 gtttactact gttttattaa gtatattctt tatactgtca gaaattgtag ttacaagtat
    20941 ttttgtttta tttgtaaaag aaggctttga aataatgctt gaaaataata gtataagagt
    21001 attggcgaca attttatcta aaattgtctt tttgttgact tgtaaaatta tttgtctatt
    21061 taaaaaggat gtacatttag atatgcccat aaagtattgg ctccctttat ttttaatacc
    21121 tatatttagt ttatttctgt ctgtttctat ctttgatgta agtaaatttt ttagtcttga
    21181 aagtttaaaa tttctaagct taatatctag tgttggtatt ttatatatta attttattgt
    21241 cttttattta tttaaattta ttatagataa aactaaacta tctatgaaat atgaactact
    21301 tgaaaaagaa ataattcata aggaagaatt aagacttagt aatgagtgtt ataaaattat
    21361 tgttgaacag actgattctg tcgttttcga atggaatatc aaagaaaata aatcatttgt
    21421 atcgcaggct tggactgaaa aatttggata taacaatgca tgtaagaata tttttaaaga
    21481 aattaaagat aaagacttag ttcattctga agataaagct atatttgaag gttttcttga
    21541 aagtattaaa aaaaagaata tgcacaatca agcagtatat cgtttaaaaa aatctaatgg
    21601 tgaatatatt tggtgtagaa catcaattac aagcatttat aatgatgaaa atgaactttt
    21661 aagagttgtc ggagtaattg tagatgtaga tagtgatata aaaaaatatg aagagttaag
    21721 aactagagca gaaagtgact cattgaccaa tatatacaat aaaggtacat ttgaaaaatt
    21781 agtggaagaa actatagtta tgaatacagg tgataaaaaa gatgcattat tcattattga
    21841 tttggatgat tttaaagaaa taaatgataa ttttggtcat ccatttggtg attttgtact
    21901 aaaaacattt gctgataaga tacaaactag ttttggtagt aaagacttag tcggaagaat
    21961 tggtggagat gaatttgttg tatatatgca agattatgtt acagaagtaa atttgcataa
    22021 aaaagctaaa gaattaaata gagtactttc ggataattac actgatttga gttttagttt
    22081 tgatgcttct gtcagtatag gtattgcaag gtatcctcaa gatggaactt cattttttga
    22141 attgtttaaa aatgcagata gagcacttta tagcataaaa gcatcaggta aaaattcata
    22201 ttgtttattt gaagaagaac tatatgtaca gtgaatttga atttagattt tatgtgagag
    22261 taagatttat atatacttgt ggctgtctga tttataaaat atgttacttt gtatattttt
    22321 atatgtttca gtaaggttaa ttaacatgag caaaggtgta agtaaattta tattagttta
    22381 agtttactta cacctttata aaaatacaaa taatagattc atttacattc ttaaatgatt
    22441 aaagctcttt accttctaaa catgcataac atatcgttat aattccagta aataagacta
    22501 aaatgcccat tactaagatt acaatttcat catctattac tccaaatgtt tttaaagtaa
    22561 cttatttcgc tttgtatcat aataatttgt ctctttttac attttaactt ctgctgagat
    22621 ttgagttaga tattcattag aatctcgcac acttatatca tatagaagat attcttcata
    22681 aacaaaatcc ccaatacgta aattattctg attaaaaaaa tttaataact tttcataagc
    22741 cttgtaaata gtttcataac tccctttatg ataagcagtt acataaagtc cctttggttt
    22801 gattgataca ggatatttct tgtactcttt attaactttt gtaaataaat atgaatatga
    22861 ttcaaagtct ttattaatta tatcttcacc tttaatgatt gagccaatcg taccataatc
    22921 actcaattca tagttgtcca taaagttaat acattcatat aaaaaatttt cttcctcatc
    22981 tcctaaaaac tgttctttat atgtaacagg tgttttgacc aagtactctt cttcatgttc
    23041 ttttaaagta atagtattcg catctatatt acatgcactt ttagtaaatg aaatagtaga
    23101 ttccattaga gcttgaatat tatttagttt ttcaatttca tttttaatat caatggtttt
    23161 cttttctaaa agctcaatta gtaaattagg tgttcttttg tctatataag ctttaatttc
    23221 ttttaaaggc atttttactt ccctaagtga agaaattata ccaaaaatgc taagttgatg
    23281 gtatgagtag tatctatatc cattttcttt ctttaattct ggtgagaaaa gacctatatc
    23341 atcataatgg aaaagtgttt ttttattgat tccacaaatc tttgcaaatt ctccagttgt
    23401 aaaataattt tttgaaactt gactcataat tataattcct ccttgactat cctgttacag
    23461 tatagtttat catagtattt tgtaaaggag tgtgattata tgaaaaaatt aattcatttt
    23521 ttaaaaccat atagagtttt aattgttgta gttttgatat ttacgttttt acaaacactt
    23581 ggaactttgt atataccaac acttacagca aatatagtaa ataatggtgt agtaaaggga
    23641 gatatagatt atattgtaaa aacaggttta atgatgatga tagtagctgg tataacagct
    23701 ttatcagctg tgttagtttg taaagtatca gcaaatcttt catctggatt ttgtagagat
    23761 attagagaag cagtatttat aaaatcacaa gatttatcaa taaatgattt taataatata
    23821 ggtacagcat caatgattac taggagtact agtgatatta ctttaatagg tcagtctgtg
    23881 tttatgttta ttcaattagt attaccagca ccaattataa ctgtttctgg tctattctta
    23941 gcatattcta tagataaagc aatgacaatt attattgttg tagtaatgtt tttattcatg
    24001 ctttcagcat ttttagttgg taaaaagctt ataaagttgt ttaaaatgat gcaaataaag
    24061 atggataata tgaatagggt gttacgtgag gtagtaactg gagtaagagt tataagagct
    24121 tttaatagga gtcgttttga aaaaaagaga tttgatagaa ctgcaataga ttattctgaa
    24181 acagcaattt caataaataa aatatttgca gtacttatgc ctattgtaat gttaataatg
    24241 aatttaggta tagtaagtat tatttggttt ggtgggatga gagtcagtaa tggaaatatg
    24301 gaaataggtc atataatggc acttgttgaa tattgtatct taattttatt ctatttaatc
    24361 atgggagtaa tggtatttat gtacatacct agagcaggtg catgtgcaga tagagtaaat
    24421 cagatattag atatagaacc tgaaattgta gatggaaatg gtcataaaga tactgtctca
    24481 gagagaggac atttagtatt taaaaatgta accttttcat atgcacaatc agaagaacct
    24541 gtgttaaata atataacatt tgaagcaaaa tctggagaag taactgcaat tataggaagc
    24601 actggctcag gcaaatctac tattgcaaat ataataccac gtttttttga aattcaatct
    24661 ggagaaatat ctataaatgg tcaggatatt aagaagattc ctcaaaaaga acttagagat
    24721 aagattggat ttgtaccaca aaaagctttt ttatttagtg gaacaataga agaaaatata
    24781 aggtatggaa aagaagatgc aagtattgaa gaagtaaagc atgctgcaag tatagctcaa
    24841 gctgatgaat ttatttatga tatggaagac aagtatgact catttgtagc acaaggtgga
    24901 aataatttgt caggtggtca aaaacagaga atatccattg caagagcgtt agttagaaag
    24961 cctgaagtat atgtctttga tgatagtttt tctgcattag attttaaaac agataaaaga
    25021 cttagaaaag cgttgaaaaa tgaaatcaaa gattcatcag ctataattat agcacaacgt
    25081 ataagtacaa tcatggatgc taatcagatt atagttttaa atgatggaaa aattgtaggt
    25141 attggaaaac ataaagattt acttgaaaat tgtgaagttt ataagcaaat tgcggattca
    25201 caacttagta aagaagaact tgcataaaat gaagaattaa tctgatattt ggaggtgtat
    25261 gatatgagtg aaaaaagaat agatgaacaa gatatagaag tacttagttt tgaagatggc
    25321 atgtcagcag aaaaagctaa ggatgcaaaa aaaactacta agagattatt aaaatatatg
    25381 gcaaaacaaa agtttaaaat attaattatt tttatttcag tattgataag ttcagcgctt
    25441 acagttttag cacctatggt tatgggaaaa gctattgacc aactatttaa tggaataaaa
    25501 actgcagtcc aaacaggtac aaaattcagt gtgaatttta gtactatggg agggatagta
    25561 tcaatacttc tagggttgta cttaattagt gcagtattta tatatattca acagtatatt
    25621 atgtcaggag ttgcacaaaa tctagttctt agcatgagaa aagatttaag tgataaactc
    25681 aataaacttc ctcttaagta ctatgattct cataaaaagg gggaaacact tagtatagta
    25741 acaaatgatt tagaaaaagt agcagatagt ttacaagaag gattaatgca acttattaca
    25801 gcagtagtta cagtagttgg ttctattgta atgatgataa gtataagtgt accacttaca
    25861 atagtatcag ctataacatt acttgtttca ttgggtatta ctgttgtaat tgcaagaaaa
    25921 tcacaagaaa gattctctga aaatcaaaag gcactaggag agttaaatag caatatagaa
    25981 gagatattta ctggtcaaat agtggttaaa gcatttagta aagaaaagga tactataaga
    26041 aactttaaaa tattaaatca aaatctttat aatgcaagta gaaaagcaca gttttcgtca
    26101 tatgcaatat ctccaattat tagatttata aacctaattg gctatgttat tatagcagtt
    26161 gtaggtggga tatttgcatc aactggagca atgactcttg gtagtataca agcgtttatt
    26221 caatatgtaa atcaagcatc agagcctact acagaaatat cttatattgt aaatatgctt
    26281 caagcagcaa tagcatctgc agagagagtt tttacagtta tggacgaggt ggaagagata
    26341 aaggatgaag aatcttcaaa ggttattagc atgcctaaag gtaaagtaca atttgagcat
    26401 gttaaatttg gatatagtga tgattttatt cttatgaaag atattaatat caatctaaat
    26461 gcaggagata agattgcaat tgttggacct acaggagctg gaaagacaac tcttgtaaat
    26521 ttacttatga gattttatga gatacaaggt ggaagaatta ctattgatgg tgttaatata
    26581 aaagatttaa agcgtggaga acttagaact atgtttggta tggttcttca agatacatgg
    26641 ctgtttaatg gaagtataaa agaaaatatt gcatatagta agtcagatgc cacaatggat
    26701 gaaattgtaa gagcagcaaa atcagcaaga gtagaccatt ttataaggac tttaccacaa
    26761 gggtatgaca ctatattgac tgaggatgct tctaatctat ctcaaggtca aaagcaactt
    26821 ctaacaattg ccagggcaat actttcagac ccatcagtat tgattcttga tgaagcaaca
    26881 tctagtgtag atactagaac agaggtagaa attcaaaagg caatgaataa cttgatgaag
    26941 ggaagaacta gttttgttat tgcacataga ttatcaacta ttcgagatgc tgatttaata
    27001 ttagtaatga aagaaggaac tattattgaa caaggaagcc ataaggaact tattgaaaag
    27061 aaaggattct atgaagaact ttataacagt caatttacaa gtgaatatga tgaagatgtt
    27121 gtatgattat caagttttag gcaactaaat gattgataaa tattaagtta aatatagtaa
    27181 catgtaaggt tatatggaat aagagtattt ctctatttca tataaccttt tttatttatc
    27241 aaaataagat aaaatttcct ttctaaatta gattgaagaa tgtatttatc aatataaaag
    27301 taaaataatc attattatta gtgaagtaaa tattgtttgc cacatatatg ccataaagat
    27361 gcacttattt tacggagatt taacaaagta gtgtaaagta tactctaaat ataaaataaa
    27421 tcaaatagag ttaaataaat tgagaggtga tataaatagt gaataaaaaa ttgaactata
    27481 gatttgaaat gaagcacaaa ataactgaag cagatgtgtt agctttaaaa tcaagactct
    27541 atccaataat gaagaaagat gaaaatgcat ctaaagatgg aaaatatctt attaggagtt
    27601 tatattttga tactcctgaa gataaagcac ttttggataa attaaatggc gttgcaataa
    27661 gagaaaagtt taggataaga ttttataata atgactgctc ttatataagg ttagagaaaa
    27721 aaatcaaaca ttacaacatg acatcaaagc tatcaactaa tttaaccaaa aaagaagtaa
    27781 taaatatact aaataatgat attgaatttc taaaagagtc gacaaattgt ttattaagag
    27841 aattttattt gaaattaaaa tgtgaaagat tagaggcaaa aagcatagtt gattacaata
    27901 gagaagcttt tatttatcca gttggaaatg taagagttac aatcgatagt gatattaaaa
    27961 cttctgtaaa ttcggtagat ttatttaata aagatttgcc aactatttcg gtaattgatg
    28021 agaatatgac tgtattggag gttaaatatg atgaatttat accagatttt ataaaggatt
    28081 taattcaaat taataagact acctctacag cagtttcaaa gtatgcttca agtagattat
    28141 atatttaaga ataaaggcta tgatttatat aaagatatac ataaataagg ttaaaaaaca
    28201 aataagttaa aaataaataa aataaaaaat aaataagtta aaaataggaa ggatgatttt
    28261 aattatgaca tttaatgata tttttaaatc aagttttata gaaaacgtat caggtttttc
    28321 atttgtggac agtgctttag cactaggttc agctttttta gtaggtttgt ttatatatat
    28381 ggtctataaa aagacttata tgggaattat gtattctcga ccattcaatg tgtcgcttgt
    28441 agcacttaca atgcttacaa cttttgtaat attggcggtt acttcaaatg tagttttatc
    28501 cttaggtatg gttggtgctt tatctatagt aagatttaga acagcaatta aagacccaat
    28561 ggatttagta tttctatttt ggtcattagg ttcaggtata gttttaggag caggtttgat
    28621 tcccttagct gtcatgggtt caataattat gggattgatt ctaatattct tttcaaataa
    28681 aacaatatct gaaactccat atatattgat ggtaaattgt aataatgaag attcagaaga
    28741 tatagcaact gataaaatta aaaaagtatt tactaaatat caaataaaat caaaaagtgt
    28801 tacaccagaa aaaggaatag aattagtgtt tgaagtaaga atgaaagatg gagaaacaag
    28861 tcttataaat gacttgagtc aagtagatgg agttactaat gcagttcttg taagttataa
    28921 tggtgactat gtagcataga gaggagtaat cttttatgaa agataaaaaa tttacccttc
    28981 ttatctcgat tatgattata tttttatgtg ctgtagttgg agtttatagt acatctagca
    29041 acaaaagtgc tgatttatat agtgatgtat atattgaaaa atattttaac agagacaagg
    29101 ttatggaagt taatatagag atagatgaaa gtgacttgaa ggatatgaat gaaaatgcta
    29161 taaaagaaga atttaaggtt gcaaaagtaa ctgtagatgg agatacatat ggaaacgtag
    29221 gtataagaac taaaggaaat tcaagtctta tatctgtagc aaatagtgat agtgatagat
    29281 acagctataa gattaatttt gataagtata atactagtca aagtatggaa gggcttactc
    29341 aattaaatct taataactgt tactctgacc catcttatat gagagagttt ttaacatata
    29401 gtatttgcga ggaaatggga ttagcgactc cagaatttgc atatgctaaa gtctctataa
    29461 atggcgaata tcatggtttg tatttggcag tagaaggatt aaaagagtct tatcttgaaa
    29521 ataattttgg taatgtaact ggagacttat ataagtcaga tgaaggaagc tcgttgcaat
    29581 ataaaggaga tgacccagaa agttactcaa acttaatcgt tgaaagtgat aaaaagacag
    29641 ctgattggtc taaaatcaca aaactattaa aatctttgga tacaggtgaa gatattgaaa
    29701 aatatcttga tgtagattct gtccttaaaa atatagcaat aaatacagct ttattaaacc
    29761 ttgatagcta tcaagggagt tttgcccata actattattt atatgagcaa gatggagtat
    29821 tttctatgtt accatgggat tttaatatgt catttggtgg atttagtggt tttggtggag
    29881 gtagtcaatc tatagcaatt gatgaaccta cgacaggtaa tttagaagac agacctctca
    29941 tatcctcgtt attaaaaaat gagacataca aaacaaaata ccataaatat ctggaagaga
    30001 tagtaacaaa atacctagat tcagactatt tagagaatat gacaacaaaa ttgcatgaca
    30061 tgatagcatc atatgtaaaa gaagacccaa cagcatttta tacttatgaa gaatttgaaa
    30121 aaaatataac atcttcaatt gaagattcta gtgataataa gggatttggt aataaagggt
    30181 ttgacaacaa taactctaat aacagtgatt ctaataataa ttctaatagt gaaaataagc
    30241 gctctggaaa tcaaagtgat gaaaaagaag ttaatgctga attaacatca agcgtagtca
    30301 aagctaatac agataatgaa actaaaaata aaactacaaa tgatagtgaa agtaagaata
    30361 atacagataa agataaaagt ggaaatgata ataatcaaaa gctagaaggt cctatgggta
    30421 aaggaggtaa gtcaatacca ggggttttgg aagttgcaga agatatgagt aaaactataa
    30481 aatctcaatt aagtggagaa acttcttcga caaagcaaaa ctctggtgat gaaagttcaa
    30541 gtggaattaa aggtagtgaa aagtttgatg aggatatgag tggtatgcca gaaccacctg
    30601 agggaatgga tggtaaaatg ccaccaggaa tgggtaatat ggataaggga gatatgaatg
    30661 gtaaaaatgg caatatgaat atggatagaa atcaagataa tccaagagaa gctggaggtt
    30721 ttggcaatag aggaggaggc tctgtgagta aaacaacaac atacttcaaa ttaattttag
    30781 gtggagcttc aatgataata atgtcgatta tgttagttgg tgtatcaagg gtaaagagaa
    30841 gaagatttat aaagtcaaaa taagattaaa attgaatata aataatttta atactgttaa
    30901 gtctaaatat ttacttagca gtattttttt agaaaataat gtatttggtt aataatataa
    30961 ggtaataaat tgataaaaat taaatacagc atattaataa tacataataa agtaataaaa
    31021 aaactgttta agtataataa cttatattta gacagttttt ttcatttata aataatataa
    31081 atgaaattga aaacatttga aggatagaaa ttggttggat aaatgtataa attacttcac
    31141 caaaaaataa tgacaaaaat tgtaactaag ttgtaataaa atggtagtta tttagcataa
    31201 aataatgtat catagaagta tattataaaa ttaataaaat aagatttttg taagaaaact
    31261 gctggctttt gatatttaga gtgagtagtt aaattatgtt taggaggggt agaatttgtt
    31321 gcaaaaagta ttatggaaat ttttaaagct agtagtcggt ttatttatat gttcagttgg
    31381 tatagtattg acgataaatt gtaaccttgg attatctccc tgggatgtat ttcatcaagg
    31441 actttcaaat catataggaa taactatagg aactgcttct ataattgtag gctctatagt
    31501 agttattgct gatgtcgttc ttggagaaaa tgtaggatgg ggaactgttt ttaacatgct
    31561 actaattgga ttctttatgg atttactttt atatagtaat ttaattccag aggctgatag
    31621 tttatttgta ggaataatta tgttgatatt aggattggtt cttttgtctg ttggaatggt
    31681 attttatatg ggaagtggtt taggaagtgg acctagagat ggtttgatgg ttgcaattca
    31741 aaagaaaaca ggaaaatcac ttaaattaat aagaggtact atagaagttg gagcattaat
    31801 agtaggattt ttattaggtg gaaaagttgg tataggaact ataataagtg catttggatt
    31861 ggggtatttc acacaaatgg tatttggctt atttaaatta gattgtagta agattaaaca
    31921 tagatttata gtagatgata taaaatttat caaagtgtat atgagtggtg agaaaaaagc
    31981 tgctgttcaa aatatagtta agtaatttaa gaataaattc aacgaaatgt taagtatttt
    32041 aaattaacat tttgtttaga tagataaatt gaatattaaa agaatattaa aatatgagga
    32101 ttgctagaac actataaaat atagatttct agcaattttt tatttgttca atattttttt
    32161 agtactagaa gtcttattct ctatttaatg aatgaattaa tttataatta gagatactaa
    32221 actttataga tattaatata aacaccttta aactgtgtat tttccaaagc ctttaaaatg
    32281 cttgtattta ttctaaataa aaaaataaaa aaatgtcaaa aaaactcttg tattatatcc
    32341 aaattttata tataattacc tatgttgttt agaaatttta aactcaatgt ttagtaaaca
    32401 aaatgtttag taaaataaaa cagaaactag gaggtgcaac atggatatag gtgaaaagat
    32461 aaaaagatta agaacagaaa aacaactgac ccaggaagag ttagctaata gatgtgaatt
    32521 gtcaaaggga tttatttctc aattagaaaa taacttaaca tcaccatcca tagctaccct
    32581 tatagatata cttgaaatac taggtacaaa tttaagggaa ttttttaatg aaatagatga
    32641 tgaaagaatc agttttacaa aagaagatat gtttgaaaca gaagatgaag atttaaaata
    32701 taaattaaag tggttaattc caaattcaca aaaaaatgaa atggagccaa taataataac
    32761 attgtatcca ggaggacagt ataaagaaga aaagccacat gaaggtgaag aatttggata
    32821 tgtattagca ggttcaatat atgtccatat aggcgaaaag aaaaataaag taaaaaaagg
    32881 agagagtttt tactttagac cgaaagcaaa tcactatata tcaaacgagg gcaaaactac
    32941 agcaaaagtg atttgggtaa gtacgccacc atcattttag aatagaggtg tttaataatt
    33001 ggtagaaaat ataatagaat taagggatat atctaaacat tatgaagaac ttactgtttt
    33061 agataatttc aatttagata taaagaaaaa tgagtttcta acattacttg gaccaagtgg
    33121 atgtggaaaa actacaacat taaaaataat agcaggattt gagtatgctg atgatggtaa
    33181 agttttattt gaaggtaagg agataaataa tttgccacca tatgaaagac aagtaaacac
    33241 agtatttcaa aaatatgctt tatttccaca catggatgtt tatgaaaatg tagcttttgg
    33301 attaaaaatt aaaaagactc caaaagatgt aatagatgct aaagtaaaag aggttttgaa
    33361 acttgttgca ctagaaggtt ttgaaagacg acaagttgaa tcattgagtg gaggacaaca
    33421 acaaagaatt gcaatagcaa gagctctagt taatgaacca aaggtattat tactagatga
    33481 accacttgga gcacttgatt taaagttaag acaagagatg caaatagaat taaagagaat
    33541 ccaaaaaaaa ttaggaataa catttgtttt tgtaactcat gaccaagaag aggctcttac
    33601 tatgtcagat actattgttg taatgtataa gggcaaaatt caacaaatgg gaacaccaca
    33661 agatatatac aatgaaccta aaaattcatt tgtagctaag tttataggtg aaagtaacat
    33721 atttgatgga attatgatag aagattataa agttaatttc tgtaatagag attttgagtg
    33781 tgttgataaa ggattcgaaa aaaacgaaaa tatagaagta gtaataagac cagaagatat
    33841 aaaaatggta aagccagaag aaggaatgtt aaaggggaaa gttacatcta cagtgtttaa
    33901 aggagtgcat tacgagatag aattgaatga aaatggaaga ttgtggatac ttcataatac
    33961 taaaaatgct gaggttggga ctgaactagg catggatata tatccagaag atatccatat
    34021 aatgagaaaa gagaataact aagatgaaaa gaaaatcttt tttagcatat ccatatgtag
    34081 tttggagtgc gatatttgta ataattcctt taatattagt agtatttttt agttttacaa
    34141 aagaatcagg tggaggttat gcctttacac ttgagaatta taaagaagta attgacccta
    34201 tatatatgaa agtttttggg cgttctattc ttttagcagg aggagctaca ttaatatgcc
    34261 ttatagttgg ttatccagtg gcatatataa tttcaaaggc tcgtgtaagt agaagaggtt
    34321 cattaatatt attgtttatt cttcctatgt ggatgaactt tcttttaaga acatatgcat
    34381 gggttgctat attaggaaaa aatggacttt taaatacatt tttaggttgg tttggaatac
    34441 aaccattagc aattttgtat actaattttg ccatactttt aggtatggtg tataactttt
    34501 taccatttat ggttcttcca atatatacag cactatcaaa gatggataat gatttgataa
    34561 acgctgctca tgacttgggt gcaaataata tgacagtttt tagaaaaatt atatttcctt
    34621 tgagtttgcc aggtgtaatg tctggaataa ctatggtatt tatgccagca gtcactactt
    34681 ttgcaatatc aagactgtta ggtggaggta aaataatgct ggttggagat ttgattgaac
    34741 aacagtttac agttgttgga gattggaact ttggttcagc tatatcgata tttatgatga
    34801 tagtaatatt aatatctatg tctataatgt caaaatttgg agatgaatct gacaaagaag
    34861 gcggtgggtt actattttaa aattaaagaa aataacttct aatatatatt tagcattagt
    34921 attcttattt ttgtatgcac ccatatttgc tttggtacta ttttctttca atgattcaaa
    34981 atcaatggca agatggaatg gatttacatg gaagtggtat ggtcaattac ttcaaaatga
    35041 gagtataatg agtgctttat attatactat tgtaatagct atattagcgt ctgtaatatc
    35101 tacaatagta ggaactataa gtgctatagg aatacataag atgagaggta agagtaagaa
    35161 attaatacta aatgtaaact atcttcctat tttaaataca gagatagtta cagcagtagc
    35221 tcttatgagt ctgtttgtat ttgtaaaaat ggaatttgga tttacaacaa tgctattggc
    35281 acatataatg ttttgtttgc catacgttat actttcagtt ttgccaaaaa tgaagcaatt
    35341 acctgataat atagaagatg cagctatgga cttgggagca acacctatat acgctcttag
    35401 aaaagtaatt ttaccacaaa taaaaccagg tatagtttct ggatttttaa ttgcatttac
    35461 tatgtcaata gatgacttta taataagttt ctttaatgct ggaaatggtg taagcaatct
    35521 ttctatagaa atctatggaa tggctagaag aggtataaaa cctgaaataa atgcattatc
    35581 aacaataatg tttgcagtgg ttctaggttt acttttacta gctaataaaa aagaatctat
    35641 agtaaggggg attaaataat gattaagttt aaaaaagcaa tatcccttat agctgtaggt
    35701 atgatgacag ttactttatt tacaggatgt aataaagcaa ctgattctac aaaagtttta
    35761 aatgtatata atgttggaga ttatatagat gagtctctta tagataagtt tgaaaaagaa
    35821 acaggaatag atgttcaata ttcaacttat gatactaatg aaatgatgta tcaaaaagta
    35881 aagagtggta gtacacacta tgatttagta tttccttcag actatatggt agagaaaatg
    35941 aaaaatgaag gtcttttgga aaaattagat tttaagaata tacctaatat gaaatattta
    36001 gataagagtt ttttaaatcc tgtatacgac aaaactaatg aatatagtgt tgcatatatg
    36061 tggggaactc ttggaatact gtacaataag aaagaagtta aagaccctat ggatagctgg
    36121 aatatacttt ggaatccaaa gtataaggga aatataatga tgtttgactc tgttagagat
    36181 actataggga taactcttaa aaaattagga tatagcatga atagtgtaaa tccaaaagaa
    36241 ataaatgaag ctaaaaatct tttaatgaaa caaaaggatt tagtattggc ttatgtaaat
    36301 gatgaaggta aggatagatt gcttggtgga gaagtggcaa tgggtatgct gtattctgga
    36361 gatgcagtta cactaatgga gcaaaatcct gaccttgatt atgctatacc taaagaggga
    36421 actaataaat gggtagatgc tatgtgtgta cctacaacag cacaaaataa gaaagaagct
    36481 gagctgttta taaacttttt attagaccca gagaatgcaa aagtaaatgc tgagtacatt
    36541 gggtattcaa cacctaatac aggagcacta aaattattag acccagaaat aactcagaat
    36601 cctgttgcat atccatctaa agaagtgctt gataaatgtg aaacttttga agatattggt
    36661 gaaaatataa aattatatga caaggcttgg atagagttaa aatcaaaata gggtcttgtt
    36721 ggtttaagta aatttactta ataaatactt aataaaactg ttctttttta gaaaatttat
    36781 tttctaatta ttgaacagtt ttattttttg tttaagttat attcatatgc aatttaaata
    36841 gtttattaat aaatgaaaac ttatttgtat aatgacttta ataataatta gaaaaaatgg
    36901 gcaacttaat agaataattg gaggtgtaaa tttataaaaa atgaatagga taaataaaaa
    36961 aatagattta ttaatattgg ctttgctcgt ttttatattt ttaattgttg gaatagtaat
    37021 actatcgatt aggacagaaa ataaattgaa tgtgttcata atgttagcaa taattttttt
    37081 tataataatg ttaacttatt tatcaaattc agtagtgggg ttgataacaa gttcaataat
    37141 tatatttatg tatacatcct atattttata taacaatatt actcacaata tggatgttga
    37201 atttatatca tatatgtgga taatagcaac accagtatct tcaattataa tgggtaatct
    37261 gaacaaaagc ataaatgaat tgcaaaatac aaataaaaaa ctatctgaac agtataagga
    37321 attagtgact attgatagtg aaactggact tagaaattta aagatttttt ataatgatgt
    37381 aaatatggag ataagtaaat ctattagaca taatactgat ttttctctta tgatagtaaa
    37441 attaccatac tacggaaacc tacagactat atttggtgaa aacaaaacta ataaaatagt
    37501 aaaatatatt ggttcaaata ttatagaatg tacaagaaat gaagatataa tttatagttt
    37561 acaaaaagat atgataggga tactaatgcc aaatacatct ttggaaggtt caaaagttgt
    37621 taaagacaga ataaagaaaa ggataaaaga attaaattta gatttaaaca ataggggaaa
    37681 atatgtaaat atagatgtca aaattgcatt tttacaatat aagagtagtt ttggagatag
    37741 tataaatttt aagaatatag ttgaagagga acttcaatat gatgtttaaa atatttaata
    37801 aaagtctatt aaaattagta gttgtattat caatagtact gacaatatca aattttagct
    37861 tatcttcata tgcatcagaa attacttcca gcacagataa ggtattaatc atatatgatt
    37921 ctaagaaaga aacagcttat aatagagata ttttaaatat tatgaggact ctattgggaa
    37981 gatttagttc agatatagag ctattaaaat tgagtaacta tgatggtgag ataaataaaa
    38041 attattacag tcatatattt attttaggaa tcaatgaaaa ctcatataat aatgataaaa
    38101 acactaaaaa cttgattagt tccttaaatt tatataaagg aactatatgt tggttaggat
    38161 atggtataga aaatcttttg gaacataaaa aatacaattt agactatgta ggaaaaacaa
    38221 acaatatagt tagtgtaaat tatagaggta aatcatataa cttggatgaa cattatgttt
    38281 ttaacattgt agaatcaaaa gatacaagta ataaagtaat aggaagtatt aatgatacct
    38341 taaataagta tccatatata ataaatgata aaaatctttt ttatgtatca aaattagatt
    38401 tagatggagt tttattttat atattttgcg attcacttaa tgatattttt aatattaaga
    38461 cgtttgataa aggacgtata tttgtaagaa tagaagatgt acatgctttt agagaaccaa
    38521 aaaatcttgt agagatagcg gattatttaa gtagtaagaa tataccattt acgattgcat
    38581 taataccagc atatgtaaat cctaaaaatc ataaggtaat aactttatca gaaagccctg
    38641 aaattgtcaa agcaataaaa tatatgcaag ataaaggtgg aactgtgata ttgcatggat
    38701 atactcatca atacaagaaa gaagaagttt ctggagaagg gtatgaattt tgggatggta
    38761 aaaaagatga acccttaaaa gaaaatatga agatatttgt caaagataga gttttgaatg
    38821 gtcttagagt atgtatagag aatggaattt atcctcttgc atttgaagcg ccacattatg
    38881 caatggaatc agagggatat aaagaattaa aaaaatattt ttctacttat atagggcaac
    38941 atcaaaataa tgataaaaaa tttagcacaa atacatatcc ttatattatt agggatacag
    39001 aggagtttaa tatatttata cccgaaaatt taggatatat agacccagaa gataagttta
    39061 cttttcaaaa tataaaagaa aatttagata aattatccat tgtaagaggt tttagtggag
    39121 ggttcttctt tcattcatat ttaaacatag agtatctaaa aaacacaata gaatatttag
    39181 aaaaacagaa tatagaattt atgaatttaa gagattttaa taattgggta aaagttgatg
    39241 aaatacaaat aagaaataat ggagatgaaa ttatagtcaa ctatgataag gacttagatg
    39301 aactaactaa aagtgatact agatttaaat ccatatccaa tattagtaaa gttttaatat
    39361 tcatagtatc tataagtgtt ttaatatttg tgattatatt tatatatttt aagagaatag
    39421 ataaaaagaa atttttaaaa taaaggattt tatattagaa tcaatatttt aaaatatttt
    39481 aggagaaatt tatgagagat ttaaatgtat cagagtattt gttcgtattt agtttgttta
    39541 gtatatggtc tttattgctt ataaatatta ttttagctat gggtggatat atattttatt
    39601 ttaaaaactt tgataaagaa ataaaagaaa ttgatgaata tcctatgata tcaatacttg
    39661 ttcctgctca taatgaagct aaagtgatag gtagaactgt ggagtctttg ctattactca
    39721 attatcctaa gagtaagatg gaacttattg ttataaatga caattcttct gataatagta
    39781 aagaaatttt agaaaatata aaggataggt acaacaatta taatttcact ataataaata
    39841 cagatagttt aacaggtgga aaaggaaagt ctaatgcatt aaatattgga tatacgattt
    39901 caaaaggaga ttttatagct gtttatgatg cagataacac accagataaa aatgcactta
    39961 ggtatctagt acaaactata gtaatgaatg atgaattagg tgctgttatt gggaaattta
    40021 ggactcgaaa taaaaataaa aacctattaa ccaaatttat aaatatagaa acattaagct
    40081 ttcaatggat gtcacaagct ggtagatggc aactttttaa tctatgtaca ataccaggaa
    40141 ctaactttat attgaggaga agtatcatag aagaaattgg aggatgggat agtaaagcaa
    40201 ttgcagaaga tacagaaata agttttagga tatataaatt gggatacaag ataaagcttg
    40261 taccacaatc tataacatgg gaacaagagc cagaaactgt taaggtgtgg ataaagcaac
    40321 gtactagatg ggcaaaaggg aatatatatg tattaatgaa atatataaaa aatatattta
    40381 aacagggaag aaataagatt gtgtttgata tagcttactt tttttctgta tattttctat
    40441 ttttaacatc tgtaattata tccgatattt tatttgtttt aagtatatct aaactagtag
    40501 aaatttctat tccaattaac ttttttctaa tatggatact atcttatctt ttatttatta
    40561 tagaagtgag tataagcctt actatagaaa aaggtgaagc aacaattgaa aatatattca
    40621 tagtggcaat aatgtatttt acatactctc aactatggct gtttgtagct ataaaaggaa
    40681 tgatagagta tctaaaagat ataattttta aaagagaggt taaatggtat aaaacagaaa
    40741 gattttgatt catgtacagg aggaattaac atgaaaaaat ttattatatc aattatatct
    40801 ttagtattgt ttttttcaaa tatatcactt atatacaaag taaatgctga tgagactaaa
    40861 gttaaaaatt ataagtttga aagagatata actattgatg gtgttatagg aagtaatagt
    40921 actttttttg aagtaaataa aaattgggat attgaagaag ttttattgca tcttaatttt
    40981 agtaagagcc aaatattaaa tggagatgtt tcaagtttaa ctgtattgat aaataatgta
    41041 ccaataaaat ctattaaatt aaatgctaag acaaattata aaaatacatt agaagtatta
    41101 gttccaaaag attatataat tcaaggatat aatgaaataa aaataaaaac atacaaaaca
    41161 atatctgata aaatttgcca agatgattcc aatactggga actggatggt tattcacaaa
    41221 gaatcatata tatcaattag atataagcag aaaaaggtgg aaaactcaat aaatgaatat
    41281 ccgtatccat atgcagaaat tgaaaataat cataaattag atacaactat agtagtacca
    41341 gataatatga ctagaggaga gactacagca gtgtttaatt tggcatcagc atttggaaaa
    41401 ataacaaaaa atgatgattt aaagttagat gttaaattat attcagaaat gaaaaattgg
    41461 tcagatgata atattatata tattggtaaa cctgaaaata cagcagaaga aattttggat
    41521 attttaagta taaaggaaca aaccctatta tcttcaaact gtataatcaa gcaagtagat
    41581 tcaccataca ataagaataa gaagatgatg gtggtaattg gtagtaatga agatgattta
    41641 ataaaggcat caaatttatt aatagaaaat agactttcta accaagtttt atcatcatca
    41701 gtacttgtaa acaaagagac taatataaaa attaataggg aacaaaaatt aaatttaggt
    41761 catttaacat taaaagattt aggatattct gactttttgt tggaaggagc atttaatcaa
    41821 caagctttgt ttgatgtcaa aataccaacg ggtaaggtat tagatgatgg ttcaaagatt
    41881 atcttaaatt taagatattc tgacaattta gattttgaaa aatctttagt tacagtgtct
    41941 ataaatgatg ttattgtggg aagtaaaaaa ttggataggt cacattctaa taatgataag
    42001 ttagaattaa aaatacctaa agatatagat aataaaaact attatcaagt taaattgaca
    42061 tttaatttga gtataaaaaa ttcgaattgt gttactagag agagtaataa tccttgggca
    42121 tatgtatcaa ataattctta tttggcgtta tctacgaaag aaaatgaaac cttatctttt
    42181 gaaaattatc cgtatccatt tgttagagat gatgaattta atgatttaac tgtgataatg
    42241 ccagattatt cagggtcaca agctatgacc tggatgttta gattaggtgt tactttaggt
    42301 gcgaatataa attcacataa tggaaatata aatgtaatta gaggaaaaga atttagtgac
    42361 aagtataagg atactaatat tgtagttttt ggagtgccac ataataattc tgttataaag
    42421 atgttaaata ataatttaaa tataaagttc gataaaaatt actccaattt tatatcaaat
    42481 gataagataa gctttattga tgattatgga aaaaatattt ctactattca attaataaaa
    42541 tcaccatata ataatcaaaa aaatatcatg gtaattagtt caatgaatga aaaaaactta
    42601 tatttaggaa tggattattt gttgaataaa agtaaagtta atgatttaaa aggagataca
    42661 ttgataattg atgaatacgg agaggtagaa gatttagctt ataatttaaa atctaagaaa
    42721 gaagtaaaag attcaagttg gaatatgagt ataaataaga caactaaagt atttttaatg
    42781 atttctttta ttactataat tatagtcatg atattatcaa tgctatatat aaaaaaatat
    42841 aaaagaagat aatatgataa atttattatt ttaaaagagg tatataattt gaggaaatat
    42901 atgaatgaat ttaaattaaa aagaagtatt ttaatctcat taataatctt aatttttata
    42961 tttatagtt
//
LOCUS       DAEHWO010000029        42050 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEHWO010000029 DAEHWO010000000
VERSION     DAEHWO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42050
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.029"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            17..685
                     /locus_tag="KNP54_001870"
     CDS             17..685
                     /locus_tag="KNP54_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBF0892772.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(776..2227)
                     /locus_tag="KNP54_001871"
     CDS             complement(776..2227)
                     /locus_tag="KNP54_001871"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBF0892773.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALILLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2243..2683)
                     /locus_tag="KNP54_001872"
     CDS             complement(2243..2683)
                     /locus_tag="KNP54_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0892774.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDINNKDKLFTSLEESKNIIEQLF"
     gene            complement(2931..3359)
                     /gene="ytfJ"
                     /locus_tag="KNP54_001873"
     CDS             complement(2931..3359)
                     /gene="ytfJ"
                     /locus_tag="KNP54_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBF0892775.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3313..3942)
                     /locus_tag="KNP54_001874"
     CDS             complement(3313..3942)
                     /locus_tag="KNP54_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBF0892776.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            complement(4104..4643)
                     /gene="scpB"
                     /locus_tag="KNP54_001875"
     CDS             complement(4104..4643)
                     /gene="scpB"
                     /locus_tag="KNP54_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBF0892777.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            complement(4645..5364)
                     /locus_tag="KNP54_001876"
     CDS             complement(4645..5364)
                     /locus_tag="KNP54_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBF0892778.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            complement(5394..5990)
                     /locus_tag="KNP54_001877"
     CDS             complement(5394..5990)
                     /locus_tag="KNP54_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBF0892779.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            6288..7124
                     /locus_tag="KNP54_001878"
     CDS             6288..7124
                     /locus_tag="KNP54_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0892780.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            7145..7567
                     /locus_tag="KNP54_001879"
     CDS             7145..7567
                     /locus_tag="KNP54_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBF0892781.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(7778..8941)
                     /locus_tag="KNP54_001880"
     CDS             complement(7778..8941)
                     /locus_tag="KNP54_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBF0892782.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(8995..9195)
                     /locus_tag="KNP54_001881"
     CDS             complement(8995..9195)
                     /locus_tag="KNP54_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBF0892783.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(9401..11077)
                     /locus_tag="KNP54_001882"
     CDS             complement(9401..11077)
                     /locus_tag="KNP54_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBF0892784.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            11294..12031
                     /locus_tag="KNP54_001883"
     CDS             11294..12031
                     /locus_tag="KNP54_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBF0892785.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            complement(12148..12606)
                     /locus_tag="KNP54_001884"
     CDS             complement(12148..12606)
                     /locus_tag="KNP54_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBF0892786.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(12888..13175)
                     /locus_tag="KNP54_001885"
     CDS             complement(12888..13175)
                     /locus_tag="KNP54_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBF0892787.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(13253..13678)
                     /gene="ruvX"
                     /locus_tag="KNP54_001886"
     CDS             complement(13253..13678)
                     /gene="ruvX"
                     /locus_tag="KNP54_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBF0892788.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(13884..16055)
                     /locus_tag="KNP54_001887"
     CDS             complement(13884..16055)
                     /locus_tag="KNP54_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892789.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDIMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            complement(16065..16322)
                     /locus_tag="KNP54_001888"
     CDS             complement(16065..16322)
                     /locus_tag="KNP54_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBF0892790.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(16347..18986)
                     /gene="alaS"
                     /locus_tag="KNP54_001889"
     CDS             complement(16347..18986)
                     /gene="alaS"
                     /locus_tag="KNP54_001889"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBF0892791.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(19054..19292)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19435..20514)
                     /gene="mnmA"
                     /locus_tag="KNP54_001890"
     CDS             complement(19435..20514)
                     /gene="mnmA"
                     /locus_tag="KNP54_001890"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBF0892792.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(20803..21243)
                     /gene="nifU"
                     /locus_tag="KNP54_001891"
     CDS             complement(20803..21243)
                     /gene="nifU"
                     /locus_tag="KNP54_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBF0892793.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(21297..22490)
                     /gene="nifS"
                     /locus_tag="KNP54_001892"
     CDS             complement(21297..22490)
                     /gene="nifS"
                     /locus_tag="KNP54_001892"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBF0892794.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(22508..22954)
                     /locus_tag="KNP54_001893"
     CDS             complement(22508..22954)
                     /locus_tag="KNP54_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBF0892795.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(23063..23833)
                     /locus_tag="KNP54_001894"
     CDS             complement(23063..23833)
                     /locus_tag="KNP54_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0892796.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(23864..25129)
                     /locus_tag="KNP54_001895"
     CDS             complement(23864..25129)
                     /locus_tag="KNP54_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBF0892797.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(25236..26021)
                     /gene="codY"
                     /locus_tag="KNP54_001896"
     CDS             complement(25236..26021)
                     /gene="codY"
                     /locus_tag="KNP54_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBF0892798.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(26186..28273)
                     /gene="topA"
                     /locus_tag="KNP54_001897"
     CDS             complement(26186..28273)
                     /gene="topA"
                     /locus_tag="KNP54_001897"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBF0892799.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNIGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(28306..29406)
                     /gene="dprA"
                     /locus_tag="KNP54_001898"
     CDS             complement(28306..29406)
                     /gene="dprA"
                     /locus_tag="KNP54_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBF0892800.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(29425..31026)
                     /locus_tag="KNP54_001899"
     CDS             complement(29425..31026)
                     /locus_tag="KNP54_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBF0892801.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFSKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(31057..31401)
                     /locus_tag="KNP54_001900"
     CDS             complement(31057..31401)
                     /locus_tag="KNP54_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBF0892802.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            31585..32748
                     /locus_tag="KNP54_001901"
     CDS             31585..32748
                     /locus_tag="KNP54_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBF0892803.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSMHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            32741..33388
                     /locus_tag="KNP54_001902"
     CDS             32741..33388
                     /locus_tag="KNP54_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892804.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTIKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            33517..34452
                     /locus_tag="KNP54_001903"
     CDS             33517..34452
                     /locus_tag="KNP54_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892805.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGN
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            34466..35563
                     /locus_tag="KNP54_001904"
     CDS             34466..35563
                     /locus_tag="KNP54_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892806.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLIISTILIALAIVKEKYKWREV"
     gene            35566..36630
                     /locus_tag="KNP54_001905"
     CDS             35566..36630
                     /locus_tag="KNP54_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0892807.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            36874..37371
                     /locus_tag="KNP54_001906"
     CDS             36874..37371
                     /locus_tag="KNP54_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBF0892808.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(37547..37795)
                     /locus_tag="KNP54_001907"
     CDS             complement(37547..37795)
                     /locus_tag="KNP54_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892809.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(37861..38877)
                     /locus_tag="KNP54_001908"
     CDS             complement(37861..38877)
                     /locus_tag="KNP54_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBF0892810.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCVNSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(38935..39702)
                     /locus_tag="KNP54_001909"
     CDS             complement(38935..39702)
                     /locus_tag="KNP54_001909"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBF0892811.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(39770..41959)
                     /locus_tag="KNP54_001910"
     CDS             complement(39770..41959)
                     /locus_tag="KNP54_001910"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBF0892812.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYGISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKKFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEGDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        13470 a         7263 c         4449 g        16868 t
ORIGIN      
        1 taggagagaa tgttatatgt ttaaaatttt tcttttttct agtgaacaat ttgtaagtct
       61 ctttatattt ggattatttt tatactattg tccaaaacta accaaaaata ttttacctta
      121 tagctataca gttgagaaga taatttgtac attacttgta ataattatgg ctctagagca
      181 attattactt atttcttcag gtaattatag tactctaaac tctttaccaa ttggaatcaa
      241 ttatatttgt atatatctgt gtatagccat actaattttt aagcagtatc atctttttaa
      301 tatatttttt tcttggagtt tagtttgttc agttggagaa ctcatttttt ctaaaaactt
      361 gggctatgaa tttcctagct taatatattt tatctttatc ttctctaagt gcttgataat
      421 ttatgcagat atatatatgg ttgatgttag aaaatttaga gttaacagat atgcacttag
      481 agataactta gctatatgtt ttatttattt ttcattcata tttttactaa acacatttac
      541 caactctagg tactattatg gttttttaag tcatagcaca actgctattt ttacgtttat
      601 ttttgttact agtattatgt acatacctgc tcttttattt aatagagata cttttatact
      661 tgaaaaaaag aaaaagagta aataatttat ttaaataaaa aataaagcca catagataat
      721 cttaaattac aaaaatatcc acgtggcttt ataaattata ttttataatt gttttttaga
      781 tttctgccaa atagtacaat gttctaacag gttctcctgt agcccccttt gctttgtatc
      841 caattgattt tgatgatgta cttgtccccg ctatatccat atgtatccaa ggagtattcc
      901 caacaaattc accaataaaa gctcctgctg ttatacatcc agcattttta ccaccagtgt
      961 ttttaaggtc tgcttcttct ccttttatca tatctttaaa ttcatcataa attggcatct
     1021 tccataccct ttcccctgat aaagtggcag ctttttctaa ttcacaataa aaatcatcat
     1081 tatttgttac tataggagtt gcgacattac ctaacaatat taaagcagca ccagttaatg
     1141 tagctacatc aaccaccttt gttacttttt cattgtttat aatgtagtat attgcatcag
     1201 ctaatgtaag tctaccttct gcatccgtat ttaaaacttc aatagttttc tttgccatag
     1261 aactaattat atctccaggt ttgtatgaac ctcctgataa agcattctca catgctgcca
     1321 ctactgctat aacatttttc tttaatttac tttgagatat agcacacata gcacctataa
     1381 cactcgcagc accagccata tctgtcttca tatctagcat agaagcattt gattttaaag
     1441 aatatccacc agtatcataa gtcaatcctt tacctactag acctaatata tctgtacttt
     1501 ctttatctcc aaagtatctc attactatga atcttggttt attaattgaa cctcttgaaa
     1561 cagcgaaaaa agcatccatt cccaatgcct ttattttttc ttcttcataa acatcaacat
     1621 taaacccaaa ctctgcacca agtttaactg tttctactgc taatgttttt ggatatatta
     1681 cgtttgatgg ttcattaact agatttctag ctattatagt tgaattagct aatattttag
     1741 ccttttctat ttgacactca acttcttttt cagtaaatat agttatagta tcaacttctt
     1801 ttctttcaaa atccttactt tttgtcttat atttatcaaa cttataattt ccaagtaata
     1861 tcccttctac aaaacaacct atttcatcac tatttaaatt aagattcagt acattaacat
     1921 cactactctt atatgcttca tttttcaata tattttttaa ttttttacac aaattcccac
     1981 ctatgattct aattttttct ctattcaata actctctctt accaaaacca acaagacaaa
     2041 catttaccaa attgttattt tcaaccaatg ttacagtatc tatactattt tctttagaat
     2101 taaaatttct gcttatcata tttattttat caaatgtcgt agaaacatct tctccctcaa
     2161 atagagctac tactgttata gcattttcta aactttttaa tatttcttta gaatacttta
     2221 tattcataat aaattctcct tttcaaaata attgttctat tatattttta gactcttcca
     2281 aagaagtaaa taatttatct ttattattta tatctaggca atccatttta tcacttatta
     2341 tagatacaaa ctttagtatt tcattatcca atatcttttc tccattttta gttattccat
     2401 aaaaagtatt tcgtctatct ctactatctt cttccctata tacatactct tgctcaacca
     2461 atttattaag tagtatacac agactagaag tagatacatg caaatctcta cttagatttt
     2521 taagctctat tttatcatgt tttcttattt ttactaaggc aaagaactgt ctttctgtaa
     2581 gaaccttatc ttttttatat ctttcgttat taataatctt tattaaatta tgaaaattat
     2641 tcatactttc taacaacaaa atagataatt ctttatcgct cataacattc acctcaaaac
     2701 taatgattta taactccctc ttatatctca aatgcgttta tatatctata atataatact
     2761 tcttttcttt ttataattat actatatatc aactttatta tctatttaaa ttgttttaaa
     2821 ctaaaatctt attagatata aatgtttaaa gtacacaaca aaatagtggg atttatatta
     2881 accccactac tttacttaaa actatataca tatttaaaaa tattttattc ttacatattg
     2941 tttttatctt gattcttatt actttgtgat atattttgaa ttttctccaa tactctagga
     3001 gttatagata atatattatc cactagattg atattactat ctaaactcat tattctagtc
     3061 tctccacttt caactactac aaatgctact ggttgtacag atatagcccc tgcgctacct
     3121 ccagcaaaat tcgtatctga tttttcattt tttaattcaa tttccctatc tttatcatca
     3181 tatccttttg agtattctcc tcctcctata ccaaagccaa ttgtaacctt tgatataggt
     3241 acaaccactg tagtatctgt ttttataggg tctcctataa tagtatttgc atctatagaa
     3301 cctttaattg tttcaagagt tgtttccata agactctgta tcgaacctgt tgctctcatt
     3361 actatcacct tccttatttc ctttattttt attcataatt ttattaatca ttattataat
     3421 attaaataaa gcttttattc ttggccttat atgtatcctt atatttccta aaacataatc
     3481 ttttgtgaaa tctggattta catttaaata cattttttct gcatcaatca tattaaataa
     3541 atttccatac aaagtattta tcaatacata tacagaagat gttaagccaa tatttccagt
     3601 tccaaaatta atatttgaat aaagttcatg tatttttatc ttttttaata atctataaat
     3661 gctcaaaagg tcatcagcta ataatatact tgaatctata ttattcttca tcccctcttt
     3721 tttatcatta tttttactat tttcagctgg ataaagttgt ctatttatat ttattaaatt
     3781 aaacatgtat tttatattaa gctttaaaca aatatctttg ttttttatat cagctattat
     3841 taagatgttt atatgagata ttaaaatcaa catagttaca cttataataa aaattacagc
     3901 tattattaaa tacttaaaat taaataattc attaagctcc atgtttatat tatcatcaaa
     3961 aaattactat ttatacttaa ttatccatat ttattttaag agaattataa ttttatattt
     4021 atacaaaaaa acacaacaac ttagagcatt ttaaatcttt taaaatttaa aattacatac
     4081 taaattattg tgattttata tttttattca tttgttgcca cttcttgata attttctata
     4141 ggtggcaatt cttcaagact ttctatattc aacaacttta aaaattcatc tgttgtttta
     4201 taaattattg gtttccctat cttattcaat ctaccagctt ctcttataag ttcattttca
     4261 aacaaagttt gtaatacctt atcacatttt actcctctta tatcctctat ttctaccttt
     4321 gttattggtt gtttgtaggc aattatagta agagtttcta atgtagcttg gctcaaactt
     4381 ttctttttct ttggttcaat aatcttcttt atatattctg catagtcttt atttgtacac
     4441 atttggtact tattctctaa cttgattatt tgaatacctc tattttgttc tctgtactcc
     4501 tcaataagta aatttaacat aatctctatt tcttttgatg aaagttcttt atttattata
     4561 tagtttaatt cttttatact tattggttca ccatatgcaa acataacaga ttctataata
     4621 tactttatat cttctctttt cattttaaca ctccgaactt tttcttatta gaatatcatc
     4681 aaaaaatata tcttgtacta cgactatttc tttttctttt ataagctcta atatagataa
     4741 aaaagtagct attatttcat cattttcata tgattttata atatttgtaa aagtaacttc
     4801 aatcttctct tttataatat ctcttatata taatattttt tcttctacag atattatttt
     4861 cttccttact attttatcta gtttctcatc attagcattt tctatctgtg atgttttaac
     4921 tttaaatata tatggaagta tattttttat tgcttctatt gatatatctt ctaaatccac
     4981 attgtcatca ataattatct cttctttatt tctataaaat ctctcattaa cataagttat
     5041 attttctttt atatcttgtg atgctacctt aaactttcta tattcttcta acttttccat
     5101 aagttctatt cttgggtctt cttcttcatc tttttgctta taaagcagat atttagactt
     5161 tatctctaaa agttttgatg ccatagttat aaattcacta gttatctcta aatccatttt
     5221 atctagcatt ttcaaataat ttagatactg cttagttata tctattatgg atatatcctt
     5281 tatatctatt ttatgctttg ttattaaatc ataaagtaaa tctaatggtc cctcatagac
     5341 ttgtaattgt atattatact tcatatcaat ccctctttaa tctgtttatt atattaaaca
     5401 aataaatata ctatttttag caacactgca tatattggtg ttaatattat tctatacata
     5461 ccagtaaata aagcaattaa taaaattata taactcatgc tttcaaattt atacaaatat
     5521 tcattccatt tatatggtac aaatgtagat ataactcccc atccatcaag tggaggtatc
     5581 ggaagtaagt taaaagctgc aaatccaata ctatataaaa acacatattc agctattgta
     5641 tttatagcat acatatgcac atacttattg ataattacac acagtatagc agtcaaaaca
     5701 ttacaaaaaa cgcctgcaag tgaaactatc aggtttccta tcttatagtt tttaaagtta
     5761 tttggattta ctggtactgg ctttgcccac cctatcttaa ggataaacat agccaaaaga
     5821 cctattgggt caacatgtct tacaggattt aatgtcattc taccataagc tttagctgta
     5881 tcatctccca ataagtgagc tgaataagca tggccaaact catgtattga tattgccata
     5941 gctataccaa ctaaacttgc tactatttct cctatattca tacttaacat taatgtacat
     6001 ctcctaaatt aaatttttaa tattattata acaattaaat agcttataat caaaattatt
     6061 ttacattata ataattttaa cttctaggca taaaattaaa atttgctttt tattttataa
     6121 cttttattat tatatcatat tcattgtgaa aatataataa ttacacctac tgtaagtgta
     6181 atattatatt gacatgaatt gacattattg tctcttagtc aatattatac aagaagtata
     6241 aaaaaatatg tgttacactt tgtataacat gaaaggaggt tacctaagtg agacaagaag
     6301 aacgcacagt atgctttgat agggaattaa aaattgaagc atatagattt aaaggcataa
     6361 tgcaaaaatt cccaaaccat tttcatgaac attatgtaat tggttttata gaaaaaggtc
     6421 aaagatattt atcttgtaaa aataaagagt ataccacaag tactggagat ttgctacttt
     6481 ttaacccttt tgatagtcat acttgtgaac aaatagatga taaagtactt gattacagat
     6541 gtattaatat taagccagaa ataatgaaaa aaactgtctt tgaaattaca ggtaaaaatt
     6601 atttaccaaa atttaatcaa cctgttatat ttcgcagtga gctagtacct ctactacaag
     6661 aattacacta tataatcatg gaagaagaat tggattttaa aaaggaagag ctttttttct
     6721 tcctaattga acaattaatt gaagaacata cagagccaaa tttgcaatct aacttggaaa
     6781 atacaaatat agaaattcaa gcagtatgtg attatctaga aaataattat gctgaacata
     6841 tagtacttga cgaattaagc actatagcag gtatgaataa gtactctcta cttcgtaatt
     6901 ttacgaaatt aaaaggtatt acaccatata gatacctaga aaatatacgg gtaaacaaag
     6961 ctaaaaagct tttagaaaaa ggcgtagaac ctatagatgc tgcgatacaa acaggatttg
     7021 tagaccaaag tcactttaca aactttttta agaattttat tggtcttaca ccaaagcagt
     7081 atcaaaatat atttataaat gatgattcaa acaactttaa ataaggtaaa aaggagaaat
     7141 aaaaatggaa actaaaaatt caaaatgtgt catggtaata gacgaaaatt taccaatggg
     7201 aattatatcc aatacagcag ctataatggg aattacacta ggaaaacatg ccccagaaac
     7261 tgttggccca gatgtaattg acaaaacagg taatagccac ttaggaatta ttgacattcc
     7321 tgtacctatt ttaaaaggaa acaaagaaat aataaaagat ttacgtaaaa aattatatac
     7381 tttggaattt aacgatttaa ctgttgtaga tttttcagat gtagcacaaa gttgcaatct
     7441 ttatgaagaa tttacacaaa agattgctag tgttccagaa gatgagttac agtattttgg
     7501 gatagcaatt tatgggaata aaaagaaagt gaataaactt actggtagta tgcctttact
     7561 tagataattg ttaaacaacc ctatatatga tattaaatca aatgatattt taagatacat
     7621 aaacttttct atatttctat aaaaatcata agattataaa atacttctat atggtaaata
     7681 aaaatacccc tatggcaaat aattacataa gggtattttt tatgtgtatt ataatcatat
     7741 ctttgtgtat tataattata tttcatctga taattattta tatcatatta tcaattattc
     7801 tttgaagcat ttgtagatag cttgccttat ttatatcctt agtatttatc aattccactt
     7861 cgcctattac ttttttatct ttacatatct ttatttttcc taaaacagtt ccctttttaa
     7921 ttggcatctt aggatttttt actatttcaa ttttcttctc aaattcttta gaacttcctt
     7981 ttttaataag agcatttaaa tcttctttag caaccaattt aactttgttt tcatcagcct
     8041 tatccaatgt aagtgttgct atattatcac ctttactaca taacttaaca ctttcataat
     8101 tagcaaatcc ataatttaaa aggctagagg catcattaaa tctttctgga gaagtctctg
     8161 ctcctaaagt tgcagcaact agatgagtat tacctctctt tgcagatgct gataaacagt
     8221 attttgcttc ttgagtaaaa ccagttttaa caccagttgc tccttgataa tgctttataa
     8281 gtttattagt atttgcaaga cctactgtaa cttgtttctt ccctactaca accttatcca
     8341 tccatgtagt taagtattta cttatcattt cgtgttttaa tagttctcta gacattaaag
     8401 ctatatcatg agcagatgta tagtggtttg caactggaag tccatttgta tttgcaaaat
     8461 gagtatcatt catatttaac tcttttgctt tagcattcat tctatcaaca aatccttcaa
     8521 cacttccagc taagtgttca gccatagcaa cacaagcatc atttgcagaa gcaacagcta
     8581 taccttttaa taatgtatca accttttgag tttctcctgg ctctaggaat atttgactac
     8641 cacccatact agatgcagtt tcacttactt gaacttcatc atcaagctta atcttgcctg
     8701 aatccaaagc ttctactata agtagcatag tcattacctt agttacacta gcaggaggaa
     8761 gctttttatg agcatccttt tcatataaaa tttgtccact accaacatcc atcaaaattg
     8821 ctgattttga agatatattt agttggttgg catcagcatt ttccttatta tttgcaaaag
     8881 aaaagcttaa aggagtaagc gcaattaata tagccaaagc agtactagct aattttttca
     8941 tcgatgtcac ctcttaaagt ttatttaaac ttattttctc acatttaact ttttttattc
     9001 taaatgccta gatatacctt gacctaaatt ttttttcttt tcaagctttt taaagtaacc
     9061 ttctaaaaca cctttattag acgcattttc tattatttca aaagcatctt cataattcat
     9121 tccatactct cctgctattt ccatttttgt ttgttttaaa gcttttatag cattttgtct
     9181 tgaaacatca tccataagaa tcctcctatc agtaaaattt atatataagt agtttttact
     9241 aataaaagat tgttataatt ggtattttat gtaatatata tttttttaaa atgagtatta
     9301 aaaagacctc ttgtaattct taagataata tcaattggat ttttgatatt actttaaaaa
     9361 ttacaagagg tctaattttc aaatttatag tttttttata ttatacttcc attatgatag
     9421 gaagtatcat tggatttcgt ttagtttttt gatataaata ttcttttagg ttttctttaa
     9481 tattattctt taaataagcc cattctttaa tatttttctc ttcacattca tttagaacat
     9541 tcttaattat atcctttgct ccatccatta aatcttctga ctctcttaca tatacgaatc
     9601 ctctggaaat tatatctgga cctgctaaga ccttaccctc atccttggaa atagtaacta
     9661 caactatcat aagaccatct tctgataaat gctttctatc ccttaaaact atattaccta
     9721 catcgcctac tcctagacca tcaactaata tgtttcctgt ttgtatacgg tttgctacct
     9781 tagcagaatt tttatctaat tctaaaacat ctcctgtttg catgacaaaa atattttctt
     9841 tatccatacc aagctgttca gctatttcag catgtctttt taacattcta tattcaccat
     9901 gagctggcat aaaaaacttt ggtctaacta atgcatgtat aagttttaat tcttcttgac
     9961 aggcatgtcc agaaacgtgt atatcagcta tatcactgta tactacttct gctccttttt
    10021 caaataagaa attgattact cttgatatta atttttcatt tcctggtatt ggatgagcag
    10081 atattataac taaatcgcca ctctttattt ctactttttt gtgctctgaa aaagccattc
    10141 tagcaagagc tgacataggt tcaccttgtg aaccagttgt tattatcact aattcactat
    10201 cttcatactt acatatatca tttaaatcta taagcatgtc atcagaaata tctaggtatc
    10261 ctaattcttt tgcaactcca actacattga ccattgagcg acctgatata gcaacttttc
    10321 tattaaactt ttcagcagta tttattattt gttgtaatct gtgtatgttg gatgcaaagg
    10381 tagcaactat aattcttctg ccatttcctt ttgcaaataa ttcgtcaaga cctaccccaa
    10441 cagtcttttc agacatagta aatcctggtt tttctgcatt agtactatct gccagcatta
    10501 aaagaactcc ttttttgctc aactcacaga ttctatgcat atccataaca tctccatcaa
    10561 taggagtcaa gtcaatctta aaatctcctg tgtggtatat tataccttgg tctgtgtgta
    10621 ttgcaataga gtaagcatct ggtatactat ggttattttt caaaaactct acttccatat
    10681 tatcaagctt tataacttgt ctaggaccta taacatttaa cttaacatta ttcattttat
    10741 gttctttaag ttttacttgt ataagaccta tactaagtct tgccccatat acaggtacat
    10801 ttattttctt taatatatat ggaagagctc ctatatggtc ttcatgtcca tgtgtaataa
    10861 atataccctt tattttatcc ctatttttta ctaaataagt tatatctggt ataactatat
    10921 ctactcctaa catttcatcc tctggaaaac taagtccagc atctataaca attatttcat
    10981 ctttatactc aacaacagtc atattttttc caacttcgtt aagtccaccc aaggccatta
    11041 cctttatctt gttggtgttc tttttgaaca attgcatcat ctccttctgt ctatttaatt
    11101 ttttaacacg ttctacaatc ataaataata tcaaatcacg cactcgctac cagttattct
    11161 tattgtacca taattcgtat catattttaa gctatattta aaatacattt aacgtattat
    11221 tttgacaaac ctattttatt ttgatatcct ctaaatatta tatgatttaa tatcggataa
    11281 tttaggagga tttatgcgtg gtaaaactca ttgtgcaata ggaatcttaa cagctatcca
    11341 aacatcttta atatttaaaa ttcctatatc tttagttgat attttagttt cagctacttt
    11401 tgctgtacta cccgatttgg ataaatctaa ttctatggtc tcaaatttca ttctaaaaaa
    11461 caatgtatcc aaatacatat atagaatttt tatatatgct gttaatatta ttattttctt
    11521 tatttcaata aatataaatg ataattttta tttaagcgca ataattacat ttgttgcaat
    11581 tataattatt gaggcaaaac taacccacac atttctaaga aaagtttttc tatcattaat
    11641 atttatacta ttagctatat gcttatacat catagaagtt gaaatatatt ttacaatttt
    11701 ttgtctaatg ttgtcaattt ttccctggtt aaagcacaga agtttttctc atagcatatt
    11761 tgcaactata atagtatatt ttttactaaa acaaatagaa ttaatcacta atattaataa
    11821 tttatctttt tatggtacga ttggttatgc aagtcatatg tttttaggag atttatttac
    11881 aaagcaagga ataccaattt tttatccgct aagcgaaaag aaaatttctt taggtttttt
    11941 aactgttgga ggaccattta gtaatttcat agaaaaatca ttcatttttg tacttatagg
    12001 attaattata ttttcaatat taaaactata agcatcttga aaactgtata tttgcatttt
    12061 atagatggtt tataataaaa aatggaagaa tagcatagaa tataaaagtt ctatactatt
    12121 cttccatcga cattaagcaa tagaagttta ttcttctgaa tcgcttactc cattacactc
    12181 gtcacatagt ccataaaatt taacatcatg atcaagtatt ttaaatttgt acaatgattg
    12241 tatctctttt tctatattgt ctaaaaggtc ttctttagct tccattatct ttccacaatt
    12301 tttacaaata agatgatgat gattatgaca gtcttcttta tgtagactaa tctcatatct
    12361 tatacatcca tcgtctaagt ttagttttga tattaatcct atttcatcca atagctgcat
    12421 tgttctatat acagtagcta agcctatttc aggacagtca accctaacta aatcatagat
    12481 ttcctcacta cttagatgtg aatggtcatg tttaagcaat atttcaacta ttgctcttct
    12541 ttgtggcgta atcttaaaac cagtttcttt taacttgtct tttaataaat ccattgtatt
    12601 tgccataaca tcacccttac tattttcaat tgataatctt tattaaataa tattgtaatt
    12661 gataattcat tttttgtcaa gacatttaaa taaatttaat ttattctcat aatataaata
    12721 tatacccata aaagatatat tattcaccaa aattcataaa ttttttggta tttttaataa
    12781 aaaacaaaaa aacagatata tactataaat gcttttacaa ttaataatgt ttaattaaag
    12841 caaatataat aaatatctga tttttatata caaacttaat tacttatcta gttaagtcca
    12901 tttgattcat cttcgtcgta atttaaacct tcttcttcca ttatagcagt atacacagct
    12961 acaacagttt catactcttc atcactttcc aaaggtatta agatttcacc ttcttcatcc
    13021 tcatcaattc taaagattaa agcttcttca gcttcttcat catctaaagg cattaatatt
    13081 gcatactctt ttccttctgc ttctaatgtt aatattattt caaattggct ttcaacgcca
    13141 ttttcgtcta ttaaatttat tatattttct tccataatgt cattcacctc aaatttattt
    13201 ttatttttat tatttatatt atatatcata agtattcaat tttatagttc ttttatgaat
    13261 ttattttaaa atctaaatat ccttgcaaaa ttattactgc tgccaacata tctataacct
    13321 tttttctttt ttgtctacta acatctgctt ctaataaaga cctctctgcc gctactgtag
    13381 aaagcctctc atcccaaaac tctacatcaa tacctgtttc tgcttttacc aattcacaaa
    13441 acttgattac tttttctcct tgtggaccta aagttccatt catatttttt ggtaatcctg
    13501 atacaatttt atttacttgt ttttctttta ttattgcttt tagctcttca atatcttttt
    13561 tcttgccaac tctttttatt gtttttacac cttgtgcagt taatcccatc aaatcactca
    13621 cagcaactcc aatagtttta tcaccaacat caagacccat tattcttcca tctaacatag
    13681 ttcctccttt atctatttat attctataga ttaaatacat attctgaacc tctcataact
    13741 aaggtcacag gcttactgct tcatataatt ttacataatc aatcataaaa attgcaatat
    13801 gattttttat gtaagcatcc agtttacatt aataatcata ttgcattttt tatttaaatc
    13861 ctatatgaac agtaaaaatt tttttagtta tttttttcaa atattatcat atttatactt
    13921 attattatta gtggtataag tatatatata gatgctgtag atgcagcaac tattccagaa
    13981 tcattaacta aaagtgtaat tatacaacca accatagatg caataaaccc tttaaacaag
    14041 attggaaaat tattcattat ctttctaaag tgtctagatg gtttaaatat aagcactgca
    14101 attactccaa ttcctacaag taaaatattt acccatacac ttgtctgtgc tagttgcata
    14161 ttcatttgaa tttttcttcc aaatgtttgt aatatctctc ctggtccatt taggaaaatt
    14221 ctctgtacaa acatacctaa atgagattca ctacctgaaa gtatatctaa agctgcaaat
    14281 gcaaaaacga caactacagc tgaaacagct aataatacag ctttcttaaa atctatttta
    14341 atgtcatata taagcattat aaacaacaaa tatgctacac attctgatat agctccacca
    14401 acatttgcac ccattgaagg atatgcacta gttataagta ttattaatga aaaaattaca
    14461 acaagtaatt tagatacctt cttataatgt aataatactg ctaagccaaa tactgcactt
    14521 gctatagtta caccttcata ttcatttcct acaccatagt acctagctcc tatgacagca
    14581 tcataactca ttatgttatt ttgcattaag tatgttccaa atacagaatc tataactatg
    14641 actaaaatag taagtgttgc aaaaaatccc atgtgcttta tatcattgtc cttaaataat
    14701 tttctaccta acaagtataa tattagcgta gttgcaaata ttcccaaaga tattgaaatt
    14761 ggagttttaa aattcatcaa aggagctaac ataaatgata gtggcattat tatgcctaat
    14821 tttataaact ccttaagtac tttgaataca cgctctttat gtggcatata atttctaaag
    14881 aaaatcgcaa acatggcaat tacccaagaa gcagatatta cgcctacaaa gccatttata
    14941 atagttgacc ttattgaaga tatagacact atcctttcat aaagtgattt tagatagcta
    15001 atattgtcct ctttatttac taaagtataa cttctaccta ccatctcttt attttcaaga
    15061 ccaaatgtac ctagtatatc tactccaaca tctaaattgg caacaattcc agcctttctt
    15121 gttgtggcag attccagtag acctttccct tctccactaa attttattat tggagaaagt
    15181 cttctcttat tcttataatc taggtcactt ggaaatgcac ttgctatata aacagtgtca
    15241 ttttctccaa ccatagaaaa tacttgttca agatatttat ttatattttt tacaatattt
    15301 ttcttcatta tatcataagt attatcattt agatttaatc tatacatatc taatctatat
    15361 gtatctccaa gttctacaaa tatagcatca ctatttttat aggatttttt agtttcatct
    15421 agtaatttat cataatctgt agatattcca aatggcattt tagaatcttt cttattaata
    15481 ttatcaatat tacctgaatc aatccttcca tattggtcca tagctactaa acataagttt
    15541 ctgtttttaa ctaattgatt attttcaatt atatcagcat ttccaattac agatgtcttt
    15601 aaaccatttt ctgataaagt ttttcctaat gaccctaaat ttgctccata ttctccatac
    15661 tcaagatttt catttataga tctattaatg cctaaatcat ttatttcttt agctttttga
    15721 cctgttgcga cttcaaaagc tttagcagta tcttggtcta ctttttgaaa attgatatag
    15781 tcttcagtag ttacactagc tcttgttcct gcacccatac ttgcataaga ccttctatca
    15841 tcagtacctt gatcccctct tatattcatg agagctacat agcctctctt ttctatctca
    15901 tttttcaaga ttggaatatt catcatactt ccaagattgg tcctattcat atcaataaat
    15961 atgaccttgc ctttttcttc agcaaaacca tagctagcag ttgatacaaa aatcataatg
    16021 actattgcaa acaacgacat aatctttttt ctcatttatt tgacctactt tctattcaga
    16081 tagtgcgtga ttacttcttc aagtatctca tctctttcaa attttttaat tatagctctt
    16141 gcatttttat gactagttat atagctagaa tcaccagaaa ggagataccc tataatttga
    16201 tttatagggt tatatccttt ttcaactaat gctttatata caaaatcaat agtatctcct
    16261 acactcatcc tatcttctgg tattccttca aatttcatag tgtagtctaa atctttttcc
    16321 aaactaaaaa cctccttgag tgaatgttat ttaacttgtg tcttaataac ctcacttgca
    16381 tagcttaaag cttggtcaac cttagataca tcactagctc ctgcttgtgc catattaggt
    16441 cttcctccac cttttcctcc agctattttt gcaacttctc taacaatatt acctgaatgt
    16501 attcccttat ctaatacatc tttagtggca gtaactacaa agttaacttt atcatctact
    16561 acatttgcaa gtactactac accagaacca agcttatctc ttagattatc tgctgtttct
    16621 cttagtgtat ccatatccat accttcaaat ttattagtta tcaaattaac tccatttact
    16681 tcaactttag aatcaaaaat agaatcaact gattgtaaac tcatcttagc tttcatatca
    16741 tgcaattctt tagataagtt tttattttct tctaataaag aacttattct ttgaattaaa
    16801 ttatcttctt tagattttaa gtttacacaa acttcagaga taattccatc tctttctttt
    16861 aggtattcat aaacagcttt tcctgttatt gcttctattc ttcttacacc tgctgctact
    16921 ccaccttcag ataatatttt gaacattcct acttgagaag tatttgtcaa gtgagttcct
    16981 ccacaaagtt ctgtagaata atctcccata gaaactactc ttacctcatc accatatttt
    17041 tcaccaaata gtgctgtagc tcctttttct ttagcttcct ttatattcat aatatcacat
    17101 tttatgtcta aagatgataa aataacatta tttacttttt cttctattac ttttaattct
    17161 tcatttgata tcgcttcaaa gtgagtaata tcaaatctaa gtctttctgg agttactaaa
    17221 gaaccagctt gattaacatg ttctcctaat acttctctta atgccttatg aagtaaatgt
    17281 gtagcactgt gatttcttgc agctgacatt ctagtttctc tatctacgag tgtcttcact
    17341 ttgtccccat tacttattct tcctgatttt attataccta tatgttttat actattatta
    17401 gcaccttttt tagtatttaa tacttctaaa actaagtttt cattagttat caatccacaa
    17461 tctccaactt gtcctccacc ttcaggatag aaagtagtgt tatctagtac tatagatacc
    17521 ttatcgcctt cttctgcact ttgaactagc tcatcatctt taactatagc ttcaatagtt
    17581 ccttcaccat aaatttcact atacccatta aatgtactgt caactgtaga ttctaatttt
    17641 gatagagggt cttccttcca actttctcca tccatatttc ctctagcatt tctagctctt
    17701 tctttttgct tttccatttc ttcattaaaa gcttcttcat ctacagatag atgttcttct
    17761 tctaatattt ctttagttaa gtctataggg aagccataag tatcatatag tttaaaagct
    17821 tcttgaccac ttaggacagt ctttccttca ttttttaata cttctatata agagttcaat
    17881 atttctgttc cttggtctat agtttcattg aatttttctt cttctattcc aactactttt
    17941 ttaatataac tttctttttc aactaaaact ggatatgctt tatcatttac ttttataact
    18001 tcatctatta gtttctgtaa aaataattct tttactccta ataacttacc atgacgagca
    18061 gcacgtctaa ggagtcttct aagaacatat cctcttcctt catttgatgg aagcactcca
    18121 tcactaacta agaatgttac agctcttata tggtcagtta ttattcttat tgatatatca
    18181 ttttttggat tctctccata ttttactcct gttaacttct caactgcttc tagtatagat
    18241 ttaattgtat caacttcaaa gatagtgtct acgccttgca taatacatcc cattctttca
    18301 agacccatac ctgtatctat attcttgttt tctaatagac tataatttcc ttcttcatct
    18361 ctatcaaatt gagtaaatac atggttccaa aattctaaat acctatcaca atcacagcct
    18421 ggtttacagt ctggattgtc acatccatat tcttctcctc tatcaaaata tatttctgaa
    18481 caaggaccac aaggacctgt acctatttcc cagaaattat catcttttcc aagtctaacc
    18541 attctttctt ctgggaaatt catttctttt gcccatatat cataagaatc atcatcttct
    18601 tcatatacag tcacccatat cttatcttct ggtatattta gccattctgt aacaaattcc
    18661 catccccatt ttattgactc tcttttaaag taatctccaa atgagaaatt acccatcatt
    18721 tcaaagaatg tagcatgtct tgcagttata cctacatttt ctatatctcc tgttcttata
    18781 catttttgag atgtacacat tctcacactt ggaggtactt ctacacctga aaagtagttt
    18841 ttcaaaggtg ccatacctga gtttataagt aacaaactct tatcattgtt tggtactaaa
    18901 gaataactat ttgctacata atgacctttt gactcaaaaa attctaaaaa cttacttctt
    18961 atttcattta atcccatctt ttccatatca tgttcctcct aataaatttt attttttcgt
    19021 ttaaataaaa aacctcgtcc ctataaataa atttataggg gcgaggacaa tcgcggtacc
    19081 accctaatta tcatacaaag tatgatatct tcggaaaacc ttagctataa cgtaactacc
    19141 gtcaatctct acttaaatct tctttataaa agataaattg ttcaagattg ctactaaaag
    19201 gctgcttcaa atatcatatt ctaagggctt ccagcatttc cctctctctg taagacatca
    19261 aatattttac tattccttat cactgtattt gttttttaat taatatacta attatattac
    19321 taaattttac aaaattaatc aatactatat tttcatatac aataaattta ttttataaac
    19381 tttatttact cttaatatac tttattgctt atttttttaa ttttttagat gtttttataa
    19441 acttttctcg attatacctc cacctactac aatatctcca tcatacatta ctacagattg
    19501 acctttagta atagctcttt gagcttcatc aaaaactatt ttaatagtat cttctcctac
    19561 tctatgaata gtagctggtg atggttttgc tgaatatctt attttggctt gaactcttaa
    19621 gggttcttct aacgtatcta ttgatataaa gttaacatct ttagcaataa gttccttttt
    19681 aaataaatct tcattgtctc caagaactat ggtattattt attggattta tgtctattac
    19741 aaacattggt tttccaaaag taattccaag cccttttctt tggcctatag tataatataa
    19801 tataccctta tgttttccaa gtatattgcc tttagtatct acaaaaaaac cttcttcaat
    19861 acgcttttta gaatgttttt ttacataatt tgcatagtca ttatctttaa caaaacaaat
    19921 ttcttgacta tcaggcttat tgtgtactgc catacccatt tccttagcaa tttctcttac
    19981 tctatctttt tcatagtcac ctattggcaa taaagtatgc tctagttgct cttgtgtaag
    20041 attataaagt gcataagttt ggtctttttt atctgtaaca gattttttta gcaaatatct
    20101 tcctgtactt tcatcctttt ctatctttgc atagtgacct gtagctacat aatcacaacc
    20161 tatttgtcta gccttcttat aaaaatcatc aaattttata tgtttattac aagctataca
    20221 gggattagga gtttttcctt ccaaatattc atctataaaa taatctatta ctttttcttt
    20281 aaacacttct ctaaaattta aaacataaaa tggtatacct attttatttg ctacccttct
    20341 agcatcttca acagcagata aagagcaaca accaccttca atttcaacaa catcatcatc
    20401 ttgccacaac ttcatagtaa caccaatgac atcatatcct tgttgtttta aaagatatgc
    20461 agctacagag ctatcaactc ctccactcat acctatcatt acttttttat tcataaacaa
    20521 atttcacctc atcttttgca ttacttatta ttataccata tagagcaagt attgtactta
    20581 tttaaaatat agcttgttct attttctaaa aaaataatca tctttattat ttgaatctta
    20641 tggattattt tgttaactaa ttaacctcta aatcaagtta aaatacttaa tttaggcaat
    20701 aaaaaatagc tattttaaaa acagctattt tttatgtcct aattatatca ttagtacttc
    20761 tttttaatca ttgtaaactt ctcataacac aatcacttat ttttattctt cttcttcaac
    20821 atcatggtca tgagcatcat ctataacata tccatccaat tctggtatat ggatattgtt
    20881 cttttgagca taatctataa gagctgcttt tacagcttgt tcagctaaaa ctgaacaatg
    20941 catctttact ggtggtaaac catccaaagc ttctgcaaca gctttatttg taagttctaa
    21001 tgcatctttt atagtttttc cttttatcat ttcagttgcc atagaagaac ttgctatagc
    21061 tgaaccacag ccaaatgttt taaacttaac atcctttatt acatctccat ctatgtctaa
    21121 aaatatcttc attatatctc cacatgtagg gtttccaact tcacctacac cacttgcatt
    21181 atcaatttct cccatatttc ttggattcat aaaatgttcc ataactttat cactatattg
    21241 cattatcttt tcctcctact caatttatgt ctatttttta tgctttatct ttatgtctat
    21301 tttactaaac cttgtttctt cgcatcatca taaagtggtg acatgcttct aagtctttct
    21361 attacttttg gtaagttctc tagtatataa tctatatcat catctgttgt aaaatctcca
    21421 actgtaagtc ttaatgaacc atgtgctatt tcatgtggta aacctattgc aagaagtaca
    21481 tgtgaagggt ctaatgaacc agaagtacat gcagaaccac ttgaaccagc aattcctaac
    21541 atatctaata ataaaagtat tccttcacct tctataaatt ggaatgcaaa gtttgcattt
    21601 cctggcaatc tattttctaa gctaccattt actcttgtgt aaggtattct ttctaacaca
    21661 ccatctatta acttatttct aagacgagtt aaagtttcta catgattttg catattttcc
    21721 ttagctaatt ctgctgcttt tccatatcca actattgcag gtatattttc tgtaccagct
    21781 cttttgcttt tttcttgtgc tccaccatgg acaaagttat gaagtcttac accttttctt
    21841 atgtataaag ctcctacacc ttttggtcca tatattttat gtgaagacat actcatcaaa
    21901 tctattccta attctttaac atctactgga atattacctg tagcttgtac tgcatcagtg
    21961 tggaataata tcttatgttt tttagctatt tcggatattt ctttaatagg ctgtatagtt
    22021 cctatttcat tatttgcaaa cattatactt ataagtatag tagtatcttt tattgaatct
    22081 tctagttgct ttaagtctac ttttccttcg ctatcaacat ctaaataagt tatttcaaat
    22141 ccatgatgtt ttgctaagta ttcacatgta tgaagtattg catggtgctc tatttttgaa
    22201 gttattatat gattaccttt gtttttatta gcataagcta caccctctag tgtccagtta
    22261 tcactttctg aaccacctgc tgtaaaatat atttcactag gttcagcatt tataagggct
    22321 gctacttgtt ctcttgcttt atccaaagca tcttttgctt ctcttccgaa tgtgtgaaaa
    22381 ctagatgcat taccaaaata atctgttagg tatggcatca ttgcatccaa tacttctttt
    22441 ttaataggtg ttgttgcaga ataatccata tacaatcttc ttttttccat tacattcatc
    22501 tccaaatcta ttttttaata tttgttatat cattttctaa tttatttttg ttatagtcat
    22561 ttatcatatc tttaagagta attgaatcta taacatcttc tatacccttt ttcatctttt
    22621 cccaaactat ttttgttaca cacatgtttg agttttcaca tacatcttca tctagtacac
    22681 agtcagataa tgcaactggt ccttctaata ctacaagtat atctcctact gttatgtctt
    22741 cagcattctt tgaaagcaaa taacctcctt gagcacctct cacacttttt actagacccg
    22801 atttttttaa agatgaaaat atttgttcta agtactgatc tgatattttt tgcttcttag
    22861 caataaattt taatgatact ggtccattgt cttgatttaa tgctaattca aacattgctt
    22921 ttagtccata tctaccttta gtagacaact tcatatatta tcacctctat atagaaatct
    22981 aattcatact gttttagtag gaattacttt caagataatt ttattatacc ctactaattt
    23041 tgtcaagatt aattttaatt ttttattttg aataaattcc ccattttcca atgttttcaa
    23101 atcctagttt tttatatatc tttccagcct cttcattatc ataaaacaaa caaggaattt
    23161 tgttttctct cagtaactct gaacatagtt taattaggca ttttgtagca agtcctttag
    23221 ctctatattt aggatgtgtt cctactccaa ttatcattgc atgagtccta ttttctgaag
    23281 tactctttgc cattgacacc acctgtttgt taatctctat acaatatcct ctacctgtcc
    23341 ttagtccatt ttttaaattc tctaaagttg tactgtgaaa ttcatctatt aagtcataaa
    23401 gttttactgt cttttttaga tttccaagcc taattctctt aacctttgca ttacaattat
    23461 tatctatcaa aaacttttta gtttgaagtt tgcaaaaatc aactaccttt aaattattaa
    23521 gtcctaatct ctttgctaaa gcatctacag cacatatttt cccagatatt tcttcgtaat
    23581 tagtattacg aagtagatta taaaaacctt caacatcata ctctccatca gaataaaaca
    23641 tcataaattc aaaatattta agtaatattg cctttatttc accatgttca cccacatctg
    23701 cccatatatt taaaaaatta tttccatatc catatctttc aatatcccct attataaaca
    23761 aattgtactc aggttctttt tttaagtatt tcataactct actgtgataa gttgagttaa
    23821 gttttataat cataatatct acccccgata cataaagttc agtctaaaaa tcactattta
    23881 gatattctaa atattttttt atatttttct cagttttatt ttcttgtggt atgtaataaa
    23941 tactatcttt tatgctatct ggtaaatact gttgctttac ataatgattt ttaaaattat
    24001 gaggatattt gtatccacaa cccctaccta tttctttaga accagaatag tgagcatcct
    24061 ttatactatt tggtatatcc ttaacaaact ctttatccag ttcatccata gctttcatta
    24121 ttgctataca tgcagaatta gactttggag atgtagccaa aagaatagta gcttctgcta
    24181 atggtatttt cgcttctgga aatccaagtt gcatagctga gtctacacat gcctttacaa
    24241 ttacaatagc atttggataa gctaaaccta tatcttcact agctattact aaaagtctcc
    24301 tacatatact tatcaaatcc ccacctttta taagtcttgc tagatagtgt atagatgcct
    24361 gtgggtcact tcctcttata gatttttgaa atgcacttaa aatatcataa tgactatcac
    24421 catttttgtc atagtttata attttattaa atgtagatgc ccttattaca tctgaatcta
    24481 tataagttat attatcctta tttggtttag ttgaatagac taccacttcc aaaatattta
    24541 aggctcttct catatctcca tcagaaagaa ttgctatatc ttcaatagca tcattattac
    24601 actcaatatc catatagcta tcttcattta atacttcaac agctcttttc agtccttttt
    24661 ctatatcaag tttttctaaa ggtttaaatt caaatacagt agacctactt aaaagagctt
    24721 tatatacata atgatatgga ttttctgtag tgctagcaat caaagttata ctcccatttt
    24781 ccataaattc taatattgat tgttgctgtt ttttattaaa actttgtatt tcatctatat
    24841 ataataggac tccatttaca ttatttatac ttccaagctc tgatatcacc ttttttatat
    24901 cttctaaaga tgaattagta gcatttattt tatagaagct tttattgctt ctttctgcta
    24961 ttatttccgc tactgtagtt ttaccaacac caggaggacc aaaaaatatc atatttggta
    25021 aaaaattaga ttgtaatatc ttagacaata tttttccatt acctattata tgactttgac
    25081 ctattacatc attcattgtt tttggtctta ttttatctgc taaaggcatt ttctcactcc
    25141 tttttaatat acttatcatt accttaataa ttcgtctaaa aaaggtatct atttgaaata
    25201 gatacctttt ctaatctaaa cctataaaat atagattatt gattgttttt taattttttt
    25261 aattcatctg taagtttgtc attaagtatt cttatatgag tacctttcat acctaatgat
    25321 cttgattcta tcacacctgc actctcaaat tttctaagtg catttactat tacagaccta
    25381 gttataccaa ctctatcagc tatcttactt gctacaagta aaccttcttt tccatccaat
    25441 tcagcaaaaa tatgttcaac tgcttcaagc tcggagtagg acagagtgcc tattgccatt
    25501 tgaactacag ctttctttct catttcttct tccaattcct cacctattgc tcttaatatt
    25561 tcaagaccaa caacagttgc actgtattca gctattacta aatcatcatc attgaatgaa
    25621 tttgaatatc ttgaaagtac caatgttcct aatctttgac cgcttcctaa tattggaact
    25681 actgtagtat atttttgtaa tcttccatgt tcttcaggaa agatttctaa tatcttctca
    25741 ccatttaaat tttctaatgt ttcatcaatt tttaacacat tttgagtata ttcatctgaa
    25801 aatttctttt gcttagtata ctcatcttct ataactgaac tgtcttgaac atcatttaaa
    25861 tgaagaccta gtactttacc ttttgcactt actacataaa cattagaact taaaacgtcg
    25921 cccaatgctc cggccagtaa atcaaaagag acactgcttc caccacttgt ttgtaatgtt
    25981 ttatttattt tccttgtttt ttgtaacact tcacttgcca tttaatcatc tcctcatgaa
    26041 atttaggcct tttaataacc ttttatattt tctaatatta ttttcacatt taatgaaaat
    26101 ttatttttct attagttgtt tacacttgaa agattatcat agattggaac ctttttcaag
    26161 agaattatgt gatttttttc aattttcact cttttccgtc attatgctct tttgtctctt
    26221 tattacattc tttattagaa cacactgttt ttgtttcaga tttagtcact ttttcaacca
    26281 tatatgaacc acacttctca caaaactctc ctgttggctt attccaagct acaaagtcac
    26341 agtttggata attagaacac ccataaaaag ctttacctct tttagatttt ctaagtataa
    26401 tatctccttc ttcacatttt ggacatttaa caccaatttt attcataatt ggtctagttg
    26461 ttttacaatc gggatagttt ttacaagcca taaactttcc aaatctacca tatttgataa
    26521 ccatattaga accacagttc tcgcaaatct catcagtttc ttcatccata tttacttttt
    26581 ctatattttc aagagcttct tcaatagcct ctttaagtgg tgcatatgat tctgatacaa
    26641 tctttttcca atctgtattg ccttcttcta taacatcaag tttactttcc atatcagcag
    26701 taaaatctac atctataaat ttatggaaat tattttccaa aatatcagta actattattc
    26761 caagttctgt tggacataga cttgttcctt gcttttcaac atactctcta ttcagtatag
    26821 tagctattgt tggagcatac gtacttggtc tacctatacc tagttcttct agtgttttta
    26881 ctaaactagc ttctgtatat cttgctggtg gttgtgtaaa atgttggtct ggcaatatat
    26941 tttctatatt taatatatct cctttttcta tacttggtaa aattttgtct tctctttctg
    27001 aaaaattata taccttggta taaccatcaa atttcatttt tgaaccagtt gccttaaata
    27061 caatatcgcc tattttacat tctacattta gtatatcaaa cactgaatct tccatttgac
    27121 tagctacaaa tcttctccaa attaaattgt ataacttgta ctggtctttg ctcaatgagg
    27181 cttttatact ctcaggagtt ctatcaactg aggttggtct tattgcctca tgggcatctt
    27241 gaaccttttt agtatccttt ttttcttttt tatcaccaat gtttttatag tagttttctc
    27301 ctaaattgtt tacgatataa cccttagctt tttcttttgc ttcatcagat attcttttag
    27361 agtcagttct tatatatgat ataagaccaa cagtaccttc accttctatg tcgatacctt
    27421 catataattc ttgtgctatc atcattgttt ttttagtagt aaaaaataac ttatttgctc
    27481 cttcttgttg aagcatactt gttgtaaatg gttttggagc tgatttacgt cttgatttag
    27541 attctatctt ctcaaccttt aaatctttac cttccatttc ttttagtatt tcatttacag
    27601 cttcttcatt ttctaattca atcttttcat catttttacc ataaaatttc aaagttatat
    27661 ctttgtcttt tactgtctta gcctcaacat ctattgtcca gtattctttt ggaataaatg
    27721 cctttatttc tttttctcta tcacaaatta actttgttgt aacagattgc actctacctg
    27781 cactaagacc ttttctaacc ttttgccata atataggact tatttgataa cctaaaagtc
    27841 tgtctagcac tcttcttgcc tgttgtgcat caaccaaatt tatatcaata tttctaggat
    27901 gtttaattgc ttttttaatt gcatccttag ttatctcatt aaactctatt ctacaatcct
    27961 cagattcatc taaatttagt atatgagcta aatgccatga tatagcttca ccttctctat
    28021 cagggtcagt tgctagatat acttgtttag attttttagc ttcttttttt aattctttta
    28081 ttacatcgcc ttttcctctt atatttatat attgaggttc aaaattattt tctatatcta
    28141 cacctaattt acttttaggt aaatctctga catgaccaac tgatgcttta actgtgtaat
    28201 gacttttccc taaaaatttt tctatagttt tagcttttgc aggcgattct acgatgacta
    28261 atgttttggc cataaaacca tacaccccca ctacctaatc ttaatttata catttaaact
    28321 gtacgtttta ttattcattt ctactactaa ctcatttagt actaattcat tgattattga
    28381 atttacatac tttatttcta taccagtata atcacaaata ctatctatat gcaagtttcc
    28441 ttctcttttt atagcttcaa ttatttgctt agacttggca tttagactta tattatcata
    28501 tttttgattt atttttttat caataatatt aaatatgtta tattcattta aaatatcatc
    28561 tatattttca attaattttg caccttcttt tataatttta tgacaacctc tactcatttg
    28621 agaatttata ttaccaggta ttgcaaaaac attttttcca tgttcaagag caaaatctac
    28681 tgtgattagt gcaccacttt ttattgctgc ttctacaaca actactccat cacttaaacc
    28741 actgataatt ctatttctat tagaaaaatg gtacggggct actgtcgagt taatattata
    28801 ctctgataat aataatcccc cattttctaa tattttattt gataaatgta aattttgttt
    28861 tggaagagga ttgtctactc ctgaaccaag tactgctata gttttagatt ttccactcat
    28921 acaacctatg tgcgagtatg catctattcc tatagctaat ccacttacta tattaactcc
    28981 atattgggat agttgacaac ttattgtttt tgcacaatta attccatagg ctgtaggttt
    29041 tcttgaacct actatagcta tattaaaatt attattaact aagcctatgt cacctttgta
    29101 gaataataac tttggagcgt tgtatatatt ctttaaattt tcaggatatt ctttatcata
    29161 tttacaaata tatttaatcg cttttttgta aagtagttct tttatatttt ctaaataagc
    29221 gtgacctcta tattttacta tattttttct aatattcaag cttatatttt ttaaattata
    29281 tatttctttt tcagaaaaat caaatatatc ttcaatattt actatttcat tttctattat
    29341 ttcaattgtt tttgttgtta ttccaccaat tgattttaac cataaataag tatctctttt
    29401 ttccataaaa tccacctcaa aaaactattt aaaataacta taataagcct ttctaaatga
    29461 aaaagcttct ataatacact gtgaatttat caaatctctt tcttctaaat ctgctattgt
    29521 tcttgccatt tttaaaagtt ttgtataact tctactgctt aggttgtatt tactaaatat
    29581 catctcagcc gtttttgaag cttctttttc cagtttacaa tatttaaata aattgtaagc
    29641 tttaatttca ctattatttt ttatattatc tttcttaaat ctatttatct gtatttttct
    29701 agcattttct actcttctct ttattttttg agagctttct tcttgtttta aagaattaaa
    29761 atctgaatat tttatagaat taacttctac aaaaatatca aacctatcta acaatggacc
    29821 tgatatttta tttatgtatc tatcaatttc gttacttcta catctacact ctgtctctga
    29881 catataataa ccacatggac atggattcat agctgcaact aacagtactc tacaaggata
    29941 ttttgcactg tactttactc tggatatatt tacatatcca tcttctatag gttgtcttaa
    30001 agtctcaagt atttttctat caaattcggc tatctcatct aaaaataaga tacctctatg
    30061 tgctaaagca atttctccag gtcttgcatc cattcctcct ccaattaaag attgctttgt
    30121 agttgtatga tgaggtgctc taaaaggtct tttatcaatt attcctttag tttcatttat
    30181 catacccaat atactataga ccttacttac ttctatcatt tcttctacac ttatatctgg
    30241 taaaattgtc cttactcttt ttgcaatcat agtttttcct gagcctggag gtccaatcat
    30301 aaacatatta tgatttccag cagcagcaat ttctgcactc ctctttacaa aataatttcc
    30361 ttttacatct ttaaagtctt catcatattt actttcttca ttattaatct tagtatattt
    30421 gcaatctata taactattat ctttttctaa ttcttcgttc tcttttcttg acttatcatc
    30481 caaaaaagac attatcctta ctttatcgac ttttatctct tcgtttaaaa aatcgacaca
    30541 ttcttttaaa cttttaatag gaattatatc aatttcatct acaaatagac tttcttttat
    30601 gttctcaatt ggtataaaaa tacgttttat gttctgagtt tttgcaccca taattatggg
    30661 caatatacct cttacttttc ttattttccc atctaatgat aattctccta taaacatact
    30721 ttctcttatg taattttcat ctttttttat taactctctt aaaaggccta tacttataga
    30781 taaatctaaa aaagctcctt ctttttttat atctgctggt gataaattta caactattct
    30841 cgtgcttgga aatttatatc cactattaag aattgctgac tttactcttt ctcttgcttc
    30901 tttaatttct ttgcctggaa gaccaacaat attaaaacta ggtattccat tgcttacatc
    30961 tacttcaacc ttaactaaaa agctgtcgat tcctactaag ttgcttgaat taataatact
    31021 taacatattt aatcctttcc aaaaacatta tcttttttaa aaagcattca ttatgtgatt
    31081 tattcttttt tctaataaat atacctctat aacatcaaat cttatgggag tgttatttaa
    31141 gttatttttt ataatataat aatttgcaac tccaattatc ttttttcttt ttttgaagct
    31201 tacagattca caagggtagc caaactttat gttagacctt gatttcacct ccacaaatat
    31261 aatttcatct tccatttttg ctattatatc tatttcccct atctttaatc tgtaattttt
    31321 ttctagtatc tttgctcctt ttgatagcaa ataattaact gctacttttt ctccaaaatc
    31381 acctttttct ttattattca ttattcactc caatacatta aattttcact tttaaattat
    31441 ggtcagtata caattttact attcaagttt ttggattgat tttatttcca tcaatattaa
    31501 taaatacttc tattgacttt attcttttat gatattattc tagttttcat aggaaaagtt
    31561 tatttttttg gaggagtgcc tttaatgaac agagaaaaat tagttgcttt tatacgatat
    31621 ttatctttat ttatattagt tgtaagctat ttgaaaaatg ttgaaaatac attgtatccg
    31681 gtcataacta tgataatatt atttctaatt ataataaata atcaagttag atttttttct
    31741 ttatcaaatg agaataaatt tatacttatt tcttactttt tagaacttat attaattttt
    31801 atactttgta attatacaaa aacttttaat tcgatttact ttgttccttt aatattagat
    31861 atatcatttt taataaagga aaaatataag tacatattgt tctcttttgt tataatatct
    31921 tctcttatta ttagtttaga taaaaatata tatttggcac tggagtcaag ctctatattg
    31981 ctaattataa ctgtactttc tatatatata gaaaatgaga atttatcaaa attatacagt
    32041 caaaatcttt atgataagct tagaatttct aaagatgaat taaaaaaagt taatgctgat
    32101 ttggaaactt atgcaagttc tatagaagaa ttagcaattt taaaagaaag aaatcgaata
    32161 tcaagagaaa tacatgatag tgtaggacat tctctttcta caacaataat acaattaaat
    32221 gctatagaaa aactcttaaa agacaaacct ctaatttatg acttagtaca tgaacttaga
    32281 gaatttgtaa ctgaaagttt tcaagatgta agaagggcta tatctgagtt aaaacctgtt
    32341 gaatatgaaa attaccaaag tttatttaaa atcaaagaat tagttaaaag ctttattaag
    32401 cttacaaata ttaatgttaa attaactatt tcaaaaaata cttggaactt atccagaaat
    32461 caatctatag ctttatatag acttatacag gaatcccttt ccaactcatc gatgcatgga
    32521 aaggcaactg aaatcagaat ttttattaca ttcaatactt caaatcttat aattactatt
    32581 agtgataatg gtataggatg tggcaatata aaaaaaggaa atggacttaa tagtatcaat
    32641 gagagaatat atgaattaaa tggtaaagtt gaatttgata attctaataa tggtttcaca
    32701 attagagctt cttttcctaa attttcaggg ggtgattttt ttgaataaaa ttaaagttct
    32761 tatagtagat gacgaaaaat taattagaaa aggtcttaaa attatattat catcttataa
    32821 tgatttagaa attgtaggag atgcttctaa tggatatgaa gctttagaat tttgtaaaat
    32881 gaatgatgta gacatagttc ttatggatat acgaatgaaa gtatgtgatg gggttctagg
    32941 tacaaggctt ataaaggaat ataataattc tataacatta ttaattttaa caacttttaa
    33001 tgatgatgaa tatataaaag atgctatgaa gtttggtgct tcaggatacc ttttaaaaga
    33061 tagctctgat gaagtattgc atgaagggat tcgttcttca ttttttggca atattgtgct
    33121 tgataaaagt gtagctgaaa aaatcatgac ctctgaaaaa acgattaaac aagagcatct
    33181 ttatgacatg tacaatttaa cagaaaaaga aatatctata attagactaa ttgcaaatgg
    33241 acttaataat aaagaaataa gtcaagaact attcttatct gaaggtacaa taaagaataa
    33301 cataactaat attttagcta aactagaact tcgtgacaga actcaactag caatctttgc
    33361 tttcaaaaat aaaattgtaa tagaataaat ctaaaaatat aaagtgactt aagtcacttt
    33421 ttttagtgac ttatagtaat agaattataa ttcacaattc tttattataa tattatagct
    33481 ttttaactta tacaaaatta ttttggaggg attactatgg atatagtcag agtaaataat
    33541 ataacaaaaa gatttaatga taaattagta cttgataaca tcagcttttc tgttaaaaaa
    33601 ggtgagatat ttggacttat tggcccaaat ggtgcaggta aatctacact tataaatata
    33661 attacaaatc ttatgttacc aaatagtggt agtattcaaa tcaatggttt agatttatca
    33721 aaagattata taaaagcaaa gtctataata gggttagttc cacaagaatt agcaattata
    33781 gaaactctta ccccttttga taacttagag tactttggag ctttctacgg tttaaaggga
    33841 aaactactta aagaaagaat cattgaagca ttagaagtta caggtcttac tgaagtcaaa
    33901 aagaaaaagg tcaaaaaatt atctggtggt atgcaaagga gattaaatat tggaatagca
    33961 ctcttaaatc atcctaaaat attaatattg gatgaaccaa ctgtaggtgt agacccccaa
    34021 tcaagaaatc atattttcaa ttttataaaa gatatatcta aaaaacatga aactactgta
    34081 atatatactt cccattatat ggaagaagtt gagcaccttt gttctaaaat ttttattatg
    34141 gatgaaggta aagaaattgc ttttggaaat aatgattatt taaaatcact cgtatctaca
    34201 aatacaaaat taattatgga aataaaaaat ataaatgccc aacttatctt tgatttaaaa
    34261 aatactaaag gtgttatatc tgttttagaa aataattcat tattagaatt ggatatagat
    34321 aaaaaattac aacttacaga tatactctct gtcattgaca aaaacaattc aaaaataatg
    34381 aaaatttctt atgaagaacc tagcctagaa gacgtatttt taaatctaac aggaaaaaat
    34441 ttaagggact aatggaggtg attttatgaa attatacatg agtgtaaaaa ctatgctaaa
    34501 gagtttaaaa agctccttta tacttaattt aatatatttt ttagctttgc ctctgatttt
    34561 atcttggttt cttgggatgg ttacagaaag catgtttcaa aaccctataa aaacagaatc
    34621 tacccccatt gttatatatg acaaagataa cacaagatta tcaaatgatt tgacaaagta
    34681 tttgaaaaat gatttatctt atatattaac agttaaaaaa gatgattcta aggcagaatt
    34741 aaagcttact atacctaaag gctatgagag tagtttatta aatgaaaaat caaatactct
    34801 aaacatagaa aaacttggaa ctcgtgatga tattgcaata ttgcttcaag atatattaga
    34861 tacttaccat gaaaaatttt atttaaataa ttctcagaaa ataagttcag aagatttttc
    34921 taaattattt aataaaaatt ctattgatac ttctataata aataacaatg ttaaacagag
    34981 ctcttatgaa tactttgctt tagtttcact aggatttctt gtaataattt ttataatgaa
    35041 caatattttg tcaaattata taagtgaatc aaagggactt tcaaaaagac tttattctat
    35101 gcctataact agagtacaat tcttaattta tgactttgta ggtttatgga tttattcatt
    35161 tatattctta ttattatatg ttttattctt tagaatactt ggaataacat ttaaaggtaa
    35221 ttttgccata ttgctcctac tttgtgcttt atcatcttat tttatgactt caatatctac
    35281 ctttgtaacc agctttttta gtaaaaaata cggtacagca atagtttatg cattactctt
    35341 tttacagaca atttttggag gtatcttcag tatgataagt gatacattta ctaagcttac
    35401 aagtttatct cctacctatt taataggaga attgtttagt aattatgaaa catttaaaac
    35461 catagattca ataggaaatt taattttcac atgtttaatt atctctacaa tattaattgc
    35521 acttgctatt gtaaaggaaa aatataaatg gagggaggtt taataatgat tagattaact
    35581 attgcaaata taaaaagata tctaaaaaat catactcttt taattaatat ggttatgctt
    35641 cctattatac taattttttc acttaatttt tttatcaaca actcgggaaa tcaatcaatg
    35701 tacttttctc cagtagcaat tgtatctgac tcttcaggaa agtatgaaca taagttaata
    35761 aatagttcta aattaaaaga aaattcattt agattaaatg aacaagataa ggctatgaat
    35821 ctattaaaaa ataataaggt ttctgctgta ttcgttttag ataaaaattt ttcaaatagt
    35881 atagataaat tacaacgacc tgtagttaaa tgctttaaaa ttgaaaatgg tggtggtagt
    35941 ctttgggcag aatcacaaat agaatctttt attactaaat cgttaaaatt gaaagtggat
    36001 aaaaatatag atgataaatt gacaaagaca aatataattg ataacaaacc agataagaat
    36061 aaaggttcat ttttagtagt cttcttgata tgctatttta tgtatattaa tgcggcacat
    36121 cttgcttctg atttatttac attaaaaaaa tcaaatgtgc taaaaagact tatctctaca
    36181 gataataaag atataaaaat aattttcagt atatttttag gactattttt tattcaatca
    36241 attgtataca cttttgctct attatgtttt tcaattatag aagactttaa tttgagtctg
    36301 aatgtattga tgattgtact agcaaatagt tttgtttcca ctggatttgt attttgggta
    36361 gctagagtat ttaaaaatga aagttctata agtcttatat ctacatttta ttctttaata
    36421 ggtctagcta tatctatctc tagtctaata ccatcaatgg ataaattatc ctttatgact
    36481 aatctttcaa agttcacacc attttattgg actatagatg ctattaaaaa caatggtagt
    36541 attttaataa atataatagc tctaatatta attggaatta tatttgtaac tgcaggaagt
    36601 cttaaactaa gagattttgc taaaaactaa taattattaa atataattag tatctatttt
    36661 tatataattg taaaagaata tttcaacata ttaaattatt ttatcttata tttttctctt
    36721 tagtttcaca catcaccaag tctaaactct atattatata ttaatatttt tgacttgtca
    36781 agttatttat gttataatat taatcattag ataattaaag cattgtacct aagttgcaat
    36841 atctaaaatt caatttggag gtataactag catatgtata aaattggtga aagtgtaatg
    36901 tatccaaaag agggagcctg ctctgtaaat gatattgtaa caaagaaaat aaatcatgag
    36961 atgcaaaaat actatgaatt aagtgtcatt tttaatagta accttaaaat ttcgattcca
    37021 gttctaaatg cagatagaat tggcatacgt ccagttatgg atggaaatga tgttgataat
    37081 tttatccaat ctattaataa aacagatggt gtatggattt ttgatagaaa agaaagactt
    37141 aaactgtacc aagataaatt tcattcagga gatgtttttg aaattgtaaa attaatcaaa
    37201 atgcttatga tacaagacag ttcaaaacaa ttgtgtagca cagataagga gtttttaaat
    37261 aaagctcaaa aatttgcttt atcagaatta gctgctgctc aatgtaaatc ctatacaatg
    37321 gtattagagg aaatgaaaaa acatatatta aattcaaaga atacaaatta aaccagtttt
    37381 ttaaactggt tttatttttt atactaatca tccatgctac tttagcttat tttaaactgc
    37441 ctaatctaat attaataaag ttatctcaat tagatagatg tattttattc aaataaaaaa
    37501 aactaagagt aaatcatatt actgatttac tcttagctaa taaaatttaa tcttcttcaa
    37561 gttctttttt ctcttgtaat aatacactta attcatttgc ttctaaaact tgtgcctctg
    37621 caatatcaag taactcttgt tgccattcca cacatttatc tttgtaatca aaaggtagcg
    37681 ttctgtcaac tatgtactta tcaatacagt cctccgcact tttaattatt tcttttcttt
    37741 catcaataaa tttttctaat tctactaagg cttcttcata agcttttcta ctcatataaa
    37801 ttcccccttt gtacaattat tctacattaa aatgattttt cctctttttt gtataaaatt
    37861 ttatttgtat ataacttttc catcaatatc ttttatagtt tgacatccag ttaatatcat
    37921 agaactactt agctctgatt gaagtttatt tacataagtt tctacaccat cagttgcacc
    37981 accaaaagaa gcagtcacaa aaggtcttcc tattaatact gcatctgcac ctaaacctat
    38041 catttttagt acgtctaaac cagttctcac tccaccatct gcaagtattg taactttacc
    38101 tttaacagca tcagcaattt ttggtaaaac ttcacatgct cctggtgtac agtcaagcac
    38161 tcttcctcca tgatttgata cgactattgc atccacacct gcttctactg ccattaaagc
    38221 atcttcaaca gtcattatac ctttcaatat aaatggtagt ttagtagact ttactaactc
    38281 ctttatttgt ttaacatttt taggaagtac tggttttcca tgtaatgata aagttactag
    38341 accacaggca tctatatcaa ctccaactgc aaatgcacca gcttcttcag ctaatcttat
    38401 cttttttata atattttcat tatcccaagg tttaataaat acaattccag ctccattata
    38461 ctttttgact acatctaaat tttccattaa aaaagcatct actgccgtat caccaaccat
    38521 tgcataaata ccactattaa cacatcctgc aactactggt tctatgtaat ctctttcatt
    38581 aatttttcca cccatattta aagtagttcc tgttactgga gctgcaaata taggtgcact
    38641 cattttcttt ccaaacatct ctatagatgt atcaggattt gatacatcat gtattactct
    38701 catatttact tttacttttt ctaaactctt gctattttct ataaaagaag aaccacttcc
    38761 tttacctccc atgccaggca cttcacctgc acaagcaacc ccattacaaa ccttacaaac
    38821 tttacaactt ccatttaaat tttctctagc actttttaat aattcattat attccatctt
    38881 taatccccca ttaactatag taatttatat tatatacatt atatcatatt atatttacag
    38941 tatatttttc aaaaaacttt ttctgtggat aggagttatg ccatattttt caatagcttc
    39001 atagtgttct ttagttccat atcctttgtg agatttaaac ccatattctg ggtatactct
    39061 atcatattgg tacattatac tatccctagt aactttagca agtatacttg ctgctgctat
    39121 tgatatagat tttgaatctc ctttcacaat tggattttga gatatgtcaa tacctggtat
    39181 tgttgctgca tcaactaata aataatccgg tgcttttttt aaacaattta tagccttttt
    39241 cattgccata tatgtagcat ttaatatatt aaattcatct atttcttcat tgtttactat
    39301 acctattcca taatctagtg cttcttcttt tattacttca aaaagttcat ctctttttgc
    39361 ctcactcagt ttcttagagt catttacacc ttctattttg gtatcttttt taaatactac
    39421 aacagaagct acaacaggtc cagcaagtgg tcctcttccc gcctcatcaa ttcctccaat
    39481 atataaataa cctttatcat agccttcgtt ctcaaatata tttatagttt ccaatctttc
    39541 ttcttctttt ctaatattat ccagcttttt tgccagtttt atagctagac cttgtacaga
    39601 ttttctttca tcaactctta acagctctat atattccata tatttttcta cttctaaagt
    39661 ctctattatt tctttaatct ccctcacact tttatcctgc ataccattcc ctcatctttc
    39721 gtttttaaaa atttaatttt taaatatatt aaaatttttt aattagagtt taattgcatc
    39781 cactatagcc acattttaaa catatactac atccacctgt atgtgcaatt ccttcacttc
    39841 cacactcagg gcacacaaat ttttcatctc cttcaaaatt tttatttatt atttctttgg
    39901 ctttttcatc tttattatct ttttcttttt tattattttt ataatattct tttttactat
    39961 tttctttttt atcttcttta ttattttctt cctttttttc atttattaaa attccactcc
    40021 ttttacatcc atctctaaat attgttactc ctttaagacc agcctcccat gccttaatat
    40081 atatattgaa aacatcttca actgtagttt caaaaggtat atttattgta gatgatatag
    40141 aagcatcaat atacttttgc catacttttt gcatgtttat tctttcttca tatcctatat
    40201 tcatagcagt aacaaaaaaa tctggtaaac attcttcatc tgtaatacct ttcttgtcca
    40261 tatactcttt aacaattgga gtatatactt tataatacac atcctcatca tgcaagcttt
    40321 cagtttttct tatatatgaa agattaaata taggttctat tccaccactg atacctatca
    40381 ttgtagatat ggaacctgta ggaggtatgg ttaaaagttg tgaatttcta agcccatact
    40441 ttttaaccat ttccttagtg tcttcattta gattttctat aaaaaactta gatttagaaa
    40501 tattttcata tttatactca ctaaatgttc catattcttt agcaattaat gctgattgct
    40561 tcacagcttc atttaacata gtcttaccaa ttaaatcaca tagttctaaa gattcatcag
    40621 aaccatatct tattcccatt tttataagca tatcagctat acccattaca cctaaaccta
    40681 tctgtctata cttatgtaca ctatctcttt gttcttgtaa tggatgcaag ttcaatccct
    40741 catctaagac atcatttaaa gctactacag cttctctaac gcaagatttt aatttattaa
    40801 tatcaaaagt agcatgttca ccaaatggtt gtattataaa ctctgacaag tttattgagc
    40861 caagtagaca acttcctcca cttggaagtg gttcttctgc acaaggattt actcctgaaa
    40921 agcaaaagtt cttatcttca ctcataaaat tatatgtttt tattttatcc caaaacaata
    40981 tacctggttc tgcataatcc cagttatttt tcacaaattt attaaataaa tcataagcat
    41041 ttactatctt aactattttt tctccagtag tttcaacttc aaaagtacaa ttatataact
    41101 ttttttctct tacagcttgc ataaattcat ctgttactct tacagaaata tttgctttag
    41161 taaccttctc caaatctgtt tttatatcta taaagtcttc tatctctgga tgatttacat
    41221 ccatagaaat cataagagct cctcttctcc ctctttgacc aattaagcca gttgtcatac
    41281 tgtaaagttc cataaaagag actgctccag tcgtatgttt tgcagcattg ttaactttcg
    41341 ctccttttgg tcttagcttt gaaatatcaa ttccaactcc tccaccataa ctaaaagttc
    41401 tagcaagttt ttttgcagta tcaaatatat cttctatgct atcttttggt ggttctatta
    41461 cataacaatt agaatatgtt actttttttc cctctttctg taatcctcta tttgctaaaa
    41521 ttcttccagc aaatagaaat tttttttgtc ttattagttt tgatattctt gaactattat
    41581 ttgaaattct ctttatccat tcatcaaaac tctcaccatt atgtctatac ttgttcttcc
    41641 atattgattt ttgtaattca tcaaactccc aagctttagt ccttatttca gagcgtcttt
    41701 ctctatataa tatgtagtgt tttgctatat cttttctatt tgattccata agtagtactt
    41761 caactatatc ttgtatttct tctacggata agcatttttc catagaatta tagtcattag
    41821 ctatttttct tgatatacca tatgccaact ctctatctac tccaccttca ctatttatac
    41881 tagctttata gacagcatct tcaatcttac ttttactaaa aagttctttt gtaccatctc
    41941 tttttattat gtatttcatt tttaaacctc caataaatta gtattaaatt aatacacaca
    42001 ttaactataa ctctaaacaa actttttata tatttgtata ttttcatatt
//
LOCUS       DAEHWO010000030        41553 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEHWO010000030 DAEHWO010000000
VERSION     DAEHWO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41553
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.030"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            217..1647
                     /locus_tag="KNP54_001911"
     CDS             217..1647
                     /locus_tag="KNP54_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBF0892813.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            2015..2593
                     /locus_tag="KNP54_001912"
     CDS             2015..2593
                     /locus_tag="KNP54_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBF0892814.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITISSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            2623..2769
                     /locus_tag="KNP54_001913"
     CDS             2623..2769
                     /locus_tag="KNP54_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBF0892815.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            3065..4444
                     /gene="scfB"
                     /locus_tag="KNP54_001914"
     CDS             3065..4444
                     /gene="scfB"
                     /locus_tag="KNP54_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBF0892816.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            4473..4970
                     /locus_tag="KNP54_001915"
     CDS             4473..4970
                     /locus_tag="KNP54_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBF0892817.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            5268..6932
                     /locus_tag="KNP54_001916"
     CDS             5268..6932
                     /locus_tag="KNP54_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBF0892818.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEAIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            6945..9395
                     /gene="recJ"
                     /locus_tag="KNP54_001917"
     CDS             6945..9395
                     /gene="recJ"
                     /locus_tag="KNP54_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBF0892819.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            9408..9920
                     /locus_tag="KNP54_001918"
     CDS             9408..9920
                     /locus_tag="KNP54_001918"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBF0892820.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            9994..12201
                     /locus_tag="KNP54_001919"
     CDS             9994..12201
                     /locus_tag="KNP54_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBF0892821.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            12226..12675
                     /locus_tag="KNP54_001920"
     CDS             12226..12675
                     /locus_tag="KNP54_001920"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBF0892822.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            12690..13304
                     /locus_tag="KNP54_001921"
     CDS             12690..13304
                     /locus_tag="KNP54_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0892823.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            13395..14951
                     /locus_tag="KNP54_001922"
     CDS             13395..14951
                     /locus_tag="KNP54_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBF0892824.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            14941..16203
                     /locus_tag="KNP54_001923"
     CDS             14941..16203
                     /locus_tag="KNP54_001923"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBF0892825.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            16277..18064
                     /gene="aspS"
                     /locus_tag="KNP54_001924"
     CDS             16277..18064
                     /gene="aspS"
                     /locus_tag="KNP54_001924"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBF0892826.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            18523..19755
                     /locus_tag="KNP54_001925"
     CDS             18523..19755
                     /locus_tag="KNP54_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBF0892827.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMNCFGIKDK"
     gene            19769..20575
                     /locus_tag="KNP54_001926"
     CDS             19769..20575
                     /locus_tag="KNP54_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBF0892828.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(20687..21556)
                     /locus_tag="KNP54_001927"
     CDS             complement(20687..21556)
                     /locus_tag="KNP54_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0892829.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            21928..23355
                     /locus_tag="KNP54_001928"
     CDS             21928..23355
                     /locus_tag="KNP54_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBF0892830.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVEIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(23432..23701)
                     /locus_tag="KNP54_001929"
     CDS             complement(23432..23701)
                     /locus_tag="KNP54_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892831.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(23704..25146)
                     /gene="nhaC"
                     /locus_tag="KNP54_001930"
     CDS             complement(23704..25146)
                     /gene="nhaC"
                     /locus_tag="KNP54_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBF0892832.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(25171..26337)
                     /locus_tag="KNP54_001931"
     CDS             complement(25171..26337)
                     /locus_tag="KNP54_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBF0892833.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(26562..28682)
                     /locus_tag="KNP54_001932"
     CDS             complement(26562..28682)
                     /locus_tag="KNP54_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0892834.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQNFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            28915..29316
                     /locus_tag="KNP54_001933"
     CDS             28915..29316
                     /locus_tag="KNP54_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892835.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            29359..29652
                     /locus_tag="KNP54_001934"
     CDS             29359..29652
                     /locus_tag="KNP54_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBF0892836.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            29667..30107
                     /locus_tag="KNP54_001935"
     CDS             29667..30107
                     /locus_tag="KNP54_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBF0892837.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(30199..30672)
                     /locus_tag="KNP54_001936"
     CDS             complement(30199..30672)
                     /locus_tag="KNP54_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBF0892838.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(30672..31460)
                     /locus_tag="KNP54_001937"
     CDS             complement(30672..31460)
                     /locus_tag="KNP54_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBF0892839.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            31788..33032
                     /locus_tag="KNP54_001938"
     CDS             31788..33032
                     /locus_tag="KNP54_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBF0892840.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALITSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            33355..34452
                     /locus_tag="KNP54_001939"
     CDS             33355..34452
                     /locus_tag="KNP54_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBF0892841.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            34443..35141
                     /locus_tag="KNP54_001940"
     CDS             34443..35141
                     /locus_tag="KNP54_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBF0892842.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            35144..36208
                     /locus_tag="KNP54_001941"
     CDS             35144..36208
                     /locus_tag="KNP54_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBF0892843.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            36391..37095
                     /locus_tag="KNP54_001942"
     CDS             36391..37095
                     /locus_tag="KNP54_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0892844.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            37088..38410
                     /locus_tag="KNP54_001943"
     CDS             37088..38410
                     /locus_tag="KNP54_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0892845.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            38597..39970
                     /locus_tag="KNP54_001944"
     CDS             38597..39970
                     /locus_tag="KNP54_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892846.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(40342..41280)
                     /gene="pdaA"
                     /locus_tag="KNP54_001945"
     CDS             complement(40342..41280)
                     /gene="pdaA"
                     /locus_tag="KNP54_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBF0892847.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        16017 a         4720 c         7078 g        13738 t
ORIGIN      
        1 aaatgagtaa taaatataaa tagtgtatac taatgggatg gaaaatgtcc actattaact
       61 ttattacccc acatatataa gataaaatta ttaatataaa atataatcta tcgacaatga
      121 atagactttt aaataaactt aatataaaat taattaaata agtgcttaaa aacgatttac
      181 tttaatgata gaatcatatt aaaggaggat aattttatgg atataaagaa taaaattaaa
      241 tctatatttt taccagaaaa aaatgactat ttagatgatg aagaatttga gtatgatata
      301 gaaaataatg aagaagattt aaaggaagat aacaaagtac atttaaatga tttaagcaga
      361 gtaaaatatg attacagaga gttaaaagac atagaaaacc aaacagaaga gatgtgtctg
      421 ctagcagtaa agcaggatgg tactataatt gagtttgtaa aggacaagac ttataaagta
      481 tgtatggaag cagtaaaaca gacatataaa tctcttaagt atataacaaa tcaaaatgag
      541 gatatttgta tagaagcagt aaaacagaac tacagagctt tgtactacat aaataataag
      601 acagaaaatg tactaattga ggctataaaa aatgcatcaa cttatgatgt catggaagta
      661 tttaaatttg tggaagagca aacagaagat gtatgtctag catttataga aagggcatct
      721 aaaaatgatg ttgcagagat attaaaagga ataaaagagc aaactccagc catatgttta
      781 gaagctgtaa aaaaagatgg aaaatcttta gcttatgtaa aggaacaaag taatagtata
      841 tgtttagaag ctgtaaaaga aaactacagt gcactatctt gtgtaaaaga gcaaactgaa
      901 gaaatatgta tagaagcagt aaaacagaat gactttgcat tgtattatgt aaatgaacag
      961 acagaaaaaa tatgcatgga agcagtaaaa agaagttata tggctctaca gtatgtaaat
     1021 aagcaaacag aagagatttg tttggaagca gtaagaattg atggaagagc attacagtac
     1081 gtaaaagagc aaacagaaga aatttgcttg gagtcagtta gacaaaatgg aaaagtactg
     1141 caatatgtaa aaaaacagac tgaaaatata tgtatagaag cagtaagagg ttcatttgaa
     1201 gaacttgaaa taaaagaaat attaagttat gtaaagatac caacagaaag aatatttgta
     1261 gaagcagtaa agcaaaatgg aaaaattctt aaatatgtag aaaatcagac agaattaata
     1321 tgtttagagg cagtaagaga aaactataat gctttagctt atgtaaagga acaaacagaa
     1381 aagatttgtt tagaagcagt taatcaaagt tatgaagcgc ttaaatatgt gaaagaacaa
     1441 acagaagaag tttgtctaaa agcagtaaaa caagattata gaatgttgaa atatgtaaat
     1501 aatcaaacag aaaaaatatg tttagaagca gtaaagcaaa attatagagc tttagaattt
     1561 gttgataatc aaacagaaaa agtttgtctt gaagcagtaa aacagaatag aaaagcacta
     1621 cagtatgtaa aacaaaaaca aagttaaaag gctaaaatat atggggaata tatgcaaata
     1681 aataaaattt gatattttgt aataaataaa atgggtatct caaaaggaac tttttagttt
     1741 gtgaggtact ctttttatat gaaatgaaat atatttttag ccttttaaca aaggggaaaa
     1801 ggtttgtttc tattttgaca taggcttttt atgcatataa agcttgataa aattgtttta
     1861 ttataattgt tttgttatat aaataataag aagaaaatta tataggtctt tttttgacca
     1921 gttttacatt tttaacaact agttttgtaa agtatattga attttctcaa aaaagaatgt
     1981 actctatata tgtaaaattt ttttggaggt aaaaatgttt aaaagatatg ctgaaaaaat
     2041 gacatctgtt ttaatttgta ataatatgat agataataat gaatctaaag tctattctta
     2101 tggatttgaa atattaatag ctttcatagt taatataacc accatgctgt ttataggttt
     2161 tttatttggt aaatttacat atgtattatt ttttttaatg tgttattgtc caataagaca
     2221 attttcagga gggtatcatg cagacaatta ttttagatgc ttattaactt ttatttttat
     2281 aattttatcc acaatcttaa ttatagaaaa tataaatata gacttattta aaaatattat
     2341 tatgattatt gcaagtgtta gttgggttgg aatttgtgtt ctgtgcccaa tagaacatag
     2401 gagtaaccct ataagtgata gggaaaagtt ggtttataag aaaactgcta tatttatatc
     2461 tacagtagtg ttattgataa caatttcaag tctttctttg agtatatttg tagattattt
     2521 cacatatagc gcatttgcca tgttttggat ttttgtgatg ttagtattag gtaagttaaa
     2581 agctaaagta taagtaaaat atgtatgagg gagagttaag ttatgaaaaa gtttattgta
     2641 agatttatga agtttgctag ctcattggca cttagcactg ctattttgtc agctaatagt
     2701 acctgtcctt ggattattca tcagcctaaa gtacccaaag aaatcagcaa tctaaagaag
     2761 acaaattaaa tacaagcact tatttataca aaattatcag gaaaaaagaa attattatat
     2821 tttaataaga ttaaaacaat ataaaatcag atacaaaatt tattttatag gagcctaata
     2881 cctatttggt aatatattag tgcgccaatt tagggggata tagtgtattt aatgaaatga
     2941 cttacggaga gtaagtcatt tttgtattgt atgtatttta tgtaaactta tgatataatg
     3001 aagggtaaag tttaattaaa ataataaaaa actttagtat agatagtaat ttaggaggta
     3061 gggtatgagt atgatacata aattttctat gaatggatat aatatcgttt tagatgtgaa
     3121 tggtggagct gttcatgtgt tagatgatgt tgcatacgat ttgttagatt tttataaaga
     3181 aaaaagtaaa gaagaaatat tagagatatt aaaatcaaaa tatcaagaag aaaaaataaa
     3241 tgaagcatat gaagaaatat taaatttgga aaaagagggt cttttatata cagaagatac
     3301 atatcaatat catccaagct ttgtacatag agagcctgta gtaaaagctt tatgtttaaa
     3361 tgtagctcat gattgtaact taaaatgtaa atactgtttt gcagctcaag gtgattttgg
     3421 aggagaaaaa gaacttatga gttttgaagt tggtaaggca gcaattgact atttgattgc
     3481 taattcagga agtagaaaga acctagagat agatttcttt ggtggagagc ctttgatgaa
     3541 ctttgaagtt gtaaaacaac tggttgacta tggaagaagt gtagaaaaag attataataa
     3601 aaatataaga tttacaataa ctacaaatgg tgtactgcta aatgatgaga ttatagatta
     3661 tataaatgaa aatatgcata atgtagtttt aagtttagat ggaagaaaag aagttaatga
     3721 taatatgaga ccaactttaa atgataaagg aagttatgat attacattac cacgatttaa
     3781 gaaacttgtg gaaaaaagag caaaagataa gtattattat ataagaggta cttttacaag
     3841 agataattta gatttttcaa aagatgttat gcattttgca gatttaggat ttaaattaac
     3901 ctctgtagag ccagtcgttg gagatgagag taatccatat gcacttagag aagaagattt
     3961 acctaagata tttgaagagt acgaaaaatt tgctgtagag tatgcagata gacaattaca
     4021 aggagatgga tttaaatttt tccattttat gatagaccta aatcaaggtc catgtgtaat
     4081 aaagagaata actggatgtg gagctggaaa tgagtatctt tctgtaactc caaatggaga
     4141 tatctatcca tgtcatcaat ttgttggaaa tgaagaattt aaaatggcaa atatatttga
     4201 tgaagaaata gtacttccag aaaatttaaa aaatatgttt agagaagctc atgtatatac
     4261 taaagaagag tgtaaacaat gttggaataa gttttactgt tcaggtggat gtcatgcaaa
     4321 tgcgataaac tttaataatg acatatcaaa accatatgaa ttaggatgtg aaatgcaaag
     4381 aaaacgtaca gagtgctcta taatgataca agctaagtta atgttagaag gagcaaccaa
     4441 ctaaatttat attttaaagg agttgtttat atatgattag agattattta gaagataaac
     4501 ctttaattga cgaaagtgta tttgtggcaa aatcagcaga tgtaattgga aatgttaaaa
     4561 taggcaaaga ttcaagtata tggtacaatg cagtagttag gggtgatgaa ggaccaataa
     4621 ctattggaga aaacactaat atacaagatt gttctatagt gcatggagat acagaaacta
     4681 taattggtaa caatgtaaca gttgggcata ggtctatagt tcatggttgt aaaattagtg
     4741 ataatgtgtt aattggtatg ggttcaataa tattggataa tgctgaaata ggagaatata
     4801 ctctgatagg agcaggtaca ctaattacat ctaataagaa gtttccgcca ggtgttttga
     4861 taatgggttc tcctggtaag gttgttagag agcttacaga agaagataaa aaatatattg
     4921 atgaatctta tgaatggtat ttagaggcag cacaaaatca aaaatattag tttaaagagt
     4981 ggttgtttca aaacatattt aaatctgttt tgaggcaacc actaatttat tttattagat
     5041 tttgttgata ttttagtttt caaaaagtat ttgattaaac cagatataaa atgtcaaaaa
     5101 taaaaattaa ctgagttaaa taattttaat aaaattggta gtatatgtga taaaattaaa
     5161 tattaaagag gatataggat attagaatat caattggtga aataatgtca tatacgataa
     5221 attaaggtgt aagtttttgg gtatacctat cttaggagtg aaaagatttg agaataagtt
     5281 atagaaattt aaagcgatat agagaaattg gatatgtttt aataaagtat ggttttagtt
     5341 ttattgtaga aagactaaat atagaaggaa ttgcctataa aataccacta tttgacccac
     5401 cagaagaaat aaaaaatatg acaactggtg agagaatgaa aagagtttta gaagaactag
     5461 gacctacata tataaaaata ggacagatat tgagtacaag aaaagacttg ttagaccagg
     5521 atataattga tgaaatatca aaactcagag atgatgtaga gaaatttgat tcaaatatag
     5581 ctattgatat atttaaagaa gaagtgggtt taagtataga agaaatattc ttagaattta
     5641 aagaagaagc aatagcagca gcttcaattg gtcaagttta tgaaggtgta cttaaaacgg
     5701 gagaagaagt aatcgtaaaa attcaaagac caaatataga gaaaataata aaatctgatt
     5761 tagagattct tagaactatt gcaaatactt taaaagattt aaaaaaggat tttaatttag
     5821 atttagtaca gatgattgaa gaatttcaaa ctcaattaat gagggaactt gattatacat
     5881 ttgaagctat aaatgcaact aaattctcta ggatatttaa aaatagtgat gaagtatata
     5941 tacctaaagt atattcagaa tataatacta agaaaatttt agtaatggag aaagttaatg
     6001 gtacaaagtt aagtgatgta gaaaaaataa ggagactagg ttataacaca aaaactattg
     6061 ttgaaatagg cgttaggtca ttttttacac aggtattatc tcatggattt tttcatgcag
     6121 acccacatcc aggtaatata ttcgtagttg ctaaaaataa gatagcatat atagattttg
     6181 gaatgattgg aattattgat aataaaactt taaaccaatt aaatgaaatt gcattagcag
     6241 gtgtagaaaa gaatgttgac aagataatat atctattgat agaaatggat gcattaaatg
     6301 gagaggctga tattaaggga cttagacagg atttacttta tctaatacat tattactatg
     6361 atatttctat agaaaaaata aatgtaacag atatattaaa tgaactattt aggtttttta
     6421 gacagtataa aatagtcatg cctgcacaat ttgtaactct tgcaaagaca gttataacat
     6481 tagaaggaac aagtagaact ttaaacacag atttttcttt tggttctatg ggaaaagagt
     6541 ttatgaaaca tcattataag agtaaattta accctaaaaa tgttgtttta agttcaagac
     6601 aaaatgtaga agaaatatta ctggacataa aaactattcc aaagcaatta aaagcaattt
     6661 taaaaaatat agaaagaaat aatataaaaa tgcaaattga agatgttaaa atgacgaggt
     6721 tagaaaattg tataatagag ctaacatctc aaatatcttt gagtttagtg ttggcatcta
     6781 ttatagtagg ttcttctctt ataattgcat ctccaaatat agaaaataat atatggataa
     6841 aatttactgc aatagcgggt ttctttatat cctttataat aggcctttgc ttagttataa
     6901 gaagtattag gtcaaaatac aaaaaagatt agggggaatt aaatttgaaa aaatggatat
     6961 tgaagtataa aggtaagata gaggaaagtg aatttagcaa aaaacttaat atttccccgg
     7021 aaatctgcca aattttaaaa aatagaggga tatgtactga aaaagattca gagatattta
     7081 tgaatccatc tttagattat ttaagagacc cttttttaat gaaagatatg caaaaagctg
     7141 ttgatagaat aaagttagca gttgagaaga acgaaaaaat ttggatttac ggagattatg
     7201 atgttgatgg tgtatcatct acatctatct tgtgcttata ttttaagagt ataggttaca
     7261 atgttgatta ctatattcct aatagattag aagaagggta tggtataaat gaagatgcta
     7321 ttaagcttat aagctctagg ggatgtgact tgattataag tgttgactgt ggaattacat
     7381 cagtgtctga ggtcaataca gcgaatgatt tgggcataga tgttataatt acagaccatc
     7441 atgaatgtca aagtgaaatt ccatcagcct ttgcagtaat aaatccaaaa caagaagatt
     7501 gtaattatcc atttgattca ctatgtggat gtggtgtagc atttaaaatg attcaagcct
     7561 tgactccaaa agaagaattt aaaactagta tgtataatta tttggaaata gtaacactag
     7621 caactatttg tgatattgtt ccacttatag atgaaaatag aataattgta aaaaatggtt
     7681 taaaatcaat gaaagaaggc aaaaatattg gattaaggga gcttataaaa gtttgtggtg
     7741 tagaaagtga taagataggt tcttctcata taggttttgc aataggtcct aggataaatg
     7801 cttcaggtcg attgggatat tcttacttag gagtagagct atttactact caatcacaag
     7861 aagaggcagt agaaatagct agtatattgg aagaaaaaaa taatgaaaga cagatgatag
     7921 aagctaagat gtatcatgaa gctgaggaaa tgctaaagtc taatagcaga tacaatgatg
     7981 acaaggtgtt ggttttagct aaagagggtt ggcaacatgg aataatagga attgtagcat
     8041 caaagttaac tgaaaaatac tacaaaccaa caattcttct aggtatagaa aatggggagg
     8101 ctactggttc agcgaggtca ataaaaggat ttaatatatt tgaagctctc ataaagtgca
     8161 aagacttgat gactaagttt ggtggtcatg aacaagcagc agggttatcc ttggattcag
     8221 acaatgtaga aattttagca aatgaaataa ataaatttgc agattataat ttaactgaag
     8281 atgatatgat agagaatgta aatgttgagt ttgaattaca agaaaatgta ataaatttaa
     8341 atcttgtaga agaattacat aagttagaac cctttggatt aaataatcct aatcctagat
     8401 ttatagttag aaattatatt ttaaaagatt tgaaagttat aggtaagaat caacaacatc
     8461 tgaaattaag catagaaaaa gagaaaagct atgaatgtat aggatttaat atgagtcatt
     8521 taaaatcaat gtataaagta ggagacaagg tagatgtact attccaatta gatgaaaata
     8581 actatatggg aaataggaaa gtacaatttt tacttaaaga tatacgattg gctcgaccta
     8641 aaagtgcaag taatgacaaa ctttcattga aattaatgtc aaaaataata ccaaaagata
     8701 ctcaaagcct gtataatata tctgtgtctg attttgaatt atttgatgga aatacagata
     8761 taaatatatt tgattatttt gaaaaagata cactaataat atctaattct ataaatggat
     8821 tttatagagc aatgtcagat atatcactta tagatttgga ttttaacata aattacaata
     8881 ttattgaaga tgttagcaaa aatactgata aattagagct tatattttct cctaatattg
     8941 ataaaataga cttaaaaaga tataataata ttattcttta tgattattta tacaataaag
     9001 gcgaatattc gtatatatat gagaataaaa gagaagaaag tgaaattata aaatattata
     9061 ataaaacaga cctattatat ttaaagaatg tagttagtaa tatagttcca tcaagagatg
     9121 aatttataac aatttataaa caagcactca taaaaaaaga aattgatttg gatatggtaa
     9181 atataaggga aacttttaat gtaattccat taaagttttt tacgatatta aatgtattta
     9241 gagaattaaa tttacttgac tttaatttaa attatgaaaa aaattctgta ctcataagaa
     9301 tattgccaaa accacagaaa aaattagact taaatgagag tttaatactc aataatctaa
     9361 aaaatttaga aaaacaatac aatagcagtt attaggaggc gtttcccatg gatttaaaaa
     9421 actttataag gaatattgat gatttcccaa agccaggcat agattttaaa gatgtgacaa
     9481 ctctatttaa agatggagat gcatttaaat atgcagtgga ttctatagtt gaagaattga
     9541 aagataaaga tgtagattta gtaataggac cagaagcaag aggatttttg atgggtacac
     9601 ctgtagcata tgctttagga gtaggatttg ttccaattag aaaacctgga aagttaccag
     9661 gtgaagttga gagttatgag tatggattag agtatggtac agatacttta gagatacata
     9721 aggatgcaat taaaaagggt caaaaagtag caatagtaga tgatttattg gctactggtg
     9781 gaactatgga agccgctgcc aagcttgtag aaaaattagg tggagaagta gtttctatgc
     9841 aatttttgat tgagctaaaa ttcttaaatg ggagagaaaa gttgtctaac tatgatgtta
     9901 attctcttat aaaatactag tacttttata atagttggta taacaccaac tattttcata
     9961 tatattaaaa ttttatacaa aataggtggt tatatgcatg ataaagaatt acaagaaata
    10021 attgaaaaaa taaaagttta tgcacctaat gcaaattttg aaatggttga aaaagcctat
    10081 aatcttgcaa aaaaagcgca tgaaggacaa tatagaaaat ctggggaacc atactttatt
    10141 catccattag cagttgcaaa tattttaata gagatggaat tagatattga aactataaca
    10201 gcaggtttac ttcatgatgt tgtagaagat acagaatata cctatgaaga cataaaaaaa
    10261 gaatttggca aagaagtagc ggatttggtt gatggagtaa ctaaacttgg tcaaataaaa
    10321 tatcgttcga aagaagaaac tcaatctgaa aatttaagaa aaatgttttt ggcaatggcg
    10381 aaggatataa gggttatact tataaaactt gctgatagat tgcacaacat gagaacatta
    10441 aaatacatgc ctccagaaaa agcaaagtat aaagcaaaag agacacttga aatttatggt
    10501 ggtatagctc atagattagg aatttccaag ataaagtggg aactagaaga cagagcatta
    10561 agatttatgg acccagaagg gtattatgat ttagttagta gagtatcaat gaagagaagt
    10621 caaagagagg attatattca aggaattgtt gaacttctta aagataagtt taaagattta
    10681 agtataccat gtgatgtata tggtagacca aagcattttt acagtatata tagaaagatg
    10741 caaaaaaaac ataagacttt tgaagagatt tttgatttaa cagcagtaag gatattggtt
    10801 gataatgtaa aggattgcta tgcagtactt ggtatagttc atacattatg gagacctatt
    10861 ccaggaagat ttaaagatta tatagcaatg ccaaaaccca atatgtatca atcattacac
    10921 accactgttg taggtcctga tggagaacct ttagagatac aaataagaac tcatgagatg
    10981 cataatatag ctgaaaatgg tatagcagcc cattggaaat ataaagaagg tatctctagc
    11041 aaagaatcaa aggttgaaga aaaacttcaa tggttgagac agatgatgga gtgggaaaaa
    11101 gatttaaaag acccacaaga gtttatggat gcacttaaag aagatgtatt taatagtcaa
    11161 gtttatgtat ttacgccaaa aggagacgta attgaattac cagcagaatc aacacctata
    11221 gattttgcct atagggttca tacaaatgta ggcaataaat gtgtaggagc taaaattgat
    11281 ggaagaatag ttcctattga ttataagctt caaaatggta atattgtcga ggtacttaca
    11341 tcatctaatt ctaatggacc aagtagggat tggcttaata tagtgaagac cccaaatgca
    11401 aaaagtagaa ttagacaatt tttcaagaag gaaagaagag aagaaaatgt tgaccgtgga
    11461 aatacaatat tagaaagaga atttaagaag catgatatac cacaaaaaga ccctcttgtt
    11521 gaaaaatata tggcattagt tgctaagaaa tttaatcagc caagtgttga ggacttaatt
    11581 gccactgtag gttatggtgg tataatgtca tctcaagtgg tatctaaggt aaaagaccta
    11641 tatttaaaag aggttaaaaa agctaaaaag gaacaacaga tacaagaaga agatttaaat
    11701 aaacacaata taagtgaaac agaatacagt aaaaagagaa agaaaaacgc atcacaagga
    11761 attatagtaa aagggcttga caatatctta gtaagatttg ctaagtgttg taatcctctt
    11821 ccaggagatg aaattgtagg atatattact aagggtaggg gagtagccat acacagagct
    11881 gattgcccaa atgcaaacaa taatggtgat ttcttccaaa atagattggt ggaggtttca
    11941 tggagttcag caggaaaagg taagtttgaa gcggaaattc aaataaaagc tattgataga
    12001 agaggaattg ttaatgaaat aactcatatt gttgcaatgg ataaacttag tttaaacgga
    12061 ataaatgcaa gaaaaggtaa ggatagtatt gtaagtataa acttacttgt agaggttaat
    12121 gacacagagg aattaaaaat tctaatgaaa aaattaaaag caattcctgg tgtagaaagt
    12181 atttatagaa tgacaaatta gagttaaaat aatagggagg aaactatgag agcagtagtg
    12241 caaagagtat cttcatctaa agttacagta gatgaaaaca ctataggtca aataaataag
    12301 gggttactag tattgttagg agtgactcat gatgataaat caagtgatgt agattatatg
    12361 attgataaaa tattgaatct gagaattttt gaagatgaaa atgacaagat gaatttatct
    12421 ctaatggata taggtggaga gcttttagta gtatctcaat ttactttata tggagattgc
    12481 agaaaaggaa gaagacctgg atttagtaat gcagctaggc cagaacttgc aaataacctt
    12541 tatgaagaat ttgtaaaaaa agcaaaagat aaaggtgtga cagttggtac aggtcaattt
    12601 gcagctcata tgatggtaga gttaactaat gatggtccag taacaatact attagactca
    12661 agtaaatctt tttaaggggg aaaactttaa tgattataaa aaaatttgta gatagttatt
    12721 ttggagtaaa tacttatgta ttaggtgatg aaaagactaa aaaatgtgca gttatagacc
    12781 caggtggaag tttagtagag acattaagtt ttgtaaaaga aaatgaatta aatattgaat
    12841 atattatcct tactcatggg catggagacc atataggata tgttaaggat attaaagaaa
    12901 aaactggtgc taaagtagtt gcacatgttg atgaaaaaga attattaaat gacaaaaata
    12961 aaaatctaag ttatacaatg agatgtggag cgcaagagtt tgatgcagat atctatgtaa
    13021 atgataaaga caagcttgaa cttggtgaat taaaaatgac tttcttgcat actccaggac
    13081 atactcaagg atgtatgtgt ataagagttg aagatgaaat gttcacagga gatactttgt
    13141 ttgctggaag tattggtaga actgatttat atagtggaga ctttaaccaa atggaaaaat
    13201 cacttaagaa attatgtaaa tatgaagatg ctgttagagt atatcctgga catggaccaa
    13261 ccagtactct aggggttgaa aagaagacaa atccttacat gtaattttat attagtattt
    13321 aaaaaagtat aaaatattta ataactatat tagtgagggg gttcttctac tgttaaatag
    13381 aaggagttaa gttgatgttg tatgtttttt taaaaggaca tgattataag tatgaagtag
    13441 cagaacttat aaaattgttt actagtgaat ttaagtttaa agactctaat gctaacaata
    13501 atatagagtc aaagcattta ataaatagat tgatttatga gaatggtgta ttattctcaa
    13561 gtactgaata ctatgaaaat ggaaacttaa agtacgagtc aatacagaat atagaaaata
    13621 tgaatcttga atttttagat ggatttgata gcagcaaaac gattgaagaa tttcttaata
    13681 gcctagatag tgaaagtaag aggaacttta aaaagctgtg taaagaaaat atcaaaaaaa
    13741 gcatgttttt agtgcttaaa caagtattta attcttatgt accatgggga attttgactg
    13801 gtattagacc agtcaaaatt gtccacaatt taatggataa aaagctagat gataatagca
    13861 taagaaccat tctaaaagat aattatttta taatagatga gaaaatagat ttagctcttg
    13921 aaatagctaa aagagagcga ttatttatgt atcctataga taaaaataaa atttctcttt
    13981 atgtaagtat tccattttgt ccaactagat gtgtatattg ttcatttcct tcaaattcat
    14041 taaaacaatt tggacattta aaaagagaat atgtttataa attgattgaa gaaattaagg
    14101 ggtttgccaa agttattaag gatactaaga aagaagttga aactctatat attggtggtg
    14161 gaactccaac tacacttgat gaggaagaat tggatttgct tataaattca ttgttcaatg
    14221 aattagattt aagtaaaatt aaagaattta ctgtagaagc aggtagacct gacactatta
    14281 cagaacaaaa actaagagtg ttaaaaaaac acaatgttag tagaattagt ataaatcctc
    14341 aaactatgaa tgatgatacc ttggtaaaga ttggaagaga gcatagagta tctgatttag
    14401 tagattgctt taatatggct cgtagaatgg gatttgataa tataaatatg gatataattt
    14461 taggtcttat agatgaagac ttaaatatgg taaagaacac attggaggag ataaaaaaac
    14521 tttctcctga aagccttaca gttcatacat tagccataaa gagagcatct aacttaaata
    14581 taaatatgga taggtataaa gaacatctaa cacaatatga agaaatggta aaaatgatag
    14641 atttatcaat gaaatatgca aaagatatgg gattaaatcc atattatatg tacagacaaa
    14701 aacatatgtt gggaaattta gaaaatatag gttatgctaa agaaggatat gagtgcattt
    14761 ataatataca gattatggaa gaaaaacaaa gtaactatgc attaggtgca ggtgctatat
    14821 cgaaatttgt ctatgtagat gaagatagaa ttgaaagagt agaaaatgta aaaaatgttg
    14881 aacaatacat tgaaagagta gatgaaatga taaaaaggaa gaaagaagag gtatataaaa
    14941 atgttgacta aagctcctag aggaactaaa gacataactc caaaagaggc ttacaaatgg
    15001 cgttatgtag aaaataaatt tagagaaata tgtgctttat atggatatga agaaatggta
    15061 acacctatat ttgaacatac agaacttttc aagagaagtg ttggagatac tacagatata
    15121 gttcaaaaag aaatgtattc ttttaaagat aaaggtgata gagaaattac cctaaagcca
    15181 gaaggtacag caggtgtagt aagagcattt atagaaaata aattatatgc agatactcaa
    15241 ccaacaaaat tattttatgt gacaccttgt tttagatatg aaagaccaca agctggtaga
    15301 caaagacaat ttcaccaatt tggaatagaa gcacttggaa gtgatactcc ttcaatggat
    15361 gctgaaataa tcgcactagc tgttcaattt tttaatgaag ttggattaaa tgatttggta
    15421 gtgagtataa attcagttgg ctgtccagtt tgtagaaaag agtacaatgc tttattaaaa
    15481 gagtatcttg actcaaaagc tgatatattg tgtgatactt gcaatgagag aagagaaaaa
    15541 aatccaatga gggttataga ctgtaaaaat cctacatgta aagaaaatat caaagatata
    15601 ccatttattg cagaccattt gtgtgatgat tgtaaatctc actttgataa acttcaagaa
    15661 tacttaaagg aaatgaatat aaactttgta attgataaaa caatagttag aggcttagat
    15721 tactatagaa aaactgcttt tgaaattata tctaatgata taggagctca aagtactgta
    15781 tgtggtggag gaagatatga tggtcttgtt gaacaattag gaggaccaaa aggtataagt
    15841 ggaattgggt ttggactagg aattgaaaga cttttactta cacttgaagg taatggaatt
    15901 gaaatagaaa accctcaatc tacggatata tttatagtaa ctataggtga agaagcaaat
    15961 acaagaagct ttaaattgtt aaaagacttg agacaaaatc atataagtgc agataaagac
    16021 catatagaga gaagtgttaa agcacaattt aaatattcag ataaaataaa ttcaaaattt
    16081 acaatagtaa ttggagatga tgaacttaaa aatgacactg cgacattaaa aaatatgaaa
    16141 acatcagagc aaactactgt aaaattaagt acattagttg aagaattaaa gcaaaagctg
    16201 taaaataaga aagtatgatg ttttgtgtat tagataaata tatagcatta aaattaaata
    16261 aaatggaggt agtatcttgg aaactttaaa gggtttaaag agaactcact actgtggaga
    16321 gttgagagaa aaaaacataa atgaagaagt cgtacttatg ggatgggtac agaaaaaaag
    16381 aaatttaggt ggtcttgtat ttgttgattt aagagataca agtggattat gtcaaatagt
    16441 ttttgataca gatgtagata aagaagcttt tgaaaaagct gaaaaattag gggctgaatt
    16501 tgtaatagct gtaaaaggaa aagtatgcga aagacaatct aaaaacccta atatgccaac
    16561 tggtgatata gaaatatttg caactgaact tagactttta aacaagtcag aaactccgcc
    16621 tatttatata aaagatgatg atgatgtttc tgaagcacta agattaaaat atagatactt
    16681 agatttaaga aaaccatcta tgcaaagaaa tttaaaatta agacataaag taatgaatat
    16741 tacaagaaat tacttatcaa acaatagatt ttgcgaaata gaaacaccat ttttaatagc
    16801 tccaacacca gaaggagcaa gagattatct agtaccaagt agagttaatc caggaaaatt
    16861 ttacgcatta ccacaatcac cacaattata taaacaatta ttgatggtaa gtggtatgga
    16921 tagatatttc caaatagtta aatgctttag agatgaagac ttaagagcag atagacaacc
    16981 agagtttaca caaatagact gcgaaatgtc ttttgttgag caagaagatg ttatgagtat
    17041 gattgaaggt ttgcttgaag cgatatttaa agaagtttta gatgtagaat tggcacttcc
    17101 acttcctaag atgacttatg cagaagctat gtctaaatat ggttcagata aaccagatac
    17161 tagatttggg tatgagttaa cagatatatc tgatgttgtt tgtaactgtg gatttaaagt
    17221 gtttgctgat gctacacaac caggaaaaag tgttagaggt ataaacgtaa aaggcaaagc
    17281 tgacgacttt actagaaaac aaatatcatc actagaagaa catgctaaga catatagagc
    17341 aaaaggtctt gcttggatga aagtaggaca agaaggagta acttctccaa tagcaaaatt
    17401 cttcaatgaa gaagaaatga acgctatact tacaagaatg aatgctgaag taggagattt
    17461 acttttattt gtagctgata aaaactcaat agtatttgat gctttaggac aagttagact
    17521 tgaagtagca aataggctta atctattgga taaaaatgta tataacttac tatgggtaac
    17581 tgagttccca gtttttgaag aagatgaaga aacaggcaca ttctcagcaa tgcatcaccc
    17641 atttacatca cctatggatg aagatttaga caagttagaa gaaggtgata agtcatcttt
    17701 aagagcgaaa gcttatgata ttgtattgaa tggttatgaa ataggtggag gaagtgttag
    17761 aatatcaaat tctgatgttc aatcaagaat gtttaaagca cttggtttta cagaggaaag
    17821 agctaatgaa aagtttggtt atttattaga agcatttaaa tatggtactc ctcctcatgc
    17881 tggtctagct tttggtcttg atagacttgt tatgttactt gcaggaactg ataatataag
    17941 agaagttatt gcattcccta aaaatcaaaa tgctgtttgc cctatgacaa atgctcctac
    18001 attggcggaa gatgagcaat tagaagaatt aagtataaaa gttgatataa aagataatga
    18061 ataatatgta gttgcaagaa actaaaatgt aaaaagtctg gatataaaat atatttatat
    18121 tcagactttt tttattagaa ttattttata ttttttctct atatattttc ataaattata
    18181 cttatattct taaccaatat aattaaaata ctatgtttaa aaattttaca taaacttggt
    18241 tgttttagaa actacttctg taacgagtac acgattttaa ttaaagaata tataacaaat
    18301 ttgaaataag tctaatatat gacttaatag attaaattaa aataataaat ttggactatt
    18361 tatctattta taacttaaat tatatcaaat tgataacaaa ctagatatta tacttttttg
    18421 tagaatagaa ttacaattat ataaagaaaa attctattaa tagtgaaaaa aaagtagaaa
    18481 aaagtagaaa ttattctttt ataaagaaag ggagggataa tattgcaaga gagagaagaa
    18541 ttagttttaa atccagttcc aaaagaggaa agagttggat ggttagctcc attgtttaat
    18601 atgcttggtt ctaacatagc tatatctgaa ctaatggttg ggggaacttt aattttagga
    18661 atgactcttt ctaatatgat tattacatca attataggga acttaatatt agttgcaatt
    18721 attatgatac aaggttatat aggttacaaa gaagggttaa atacgtatgt attagctaag
    18781 ggggcatttg gagagatagg aggaaagtat cttatatctc tattacttgg tataactagt
    18841 tttggatggt ttggtgtaca agcaggggtt gcaggactat cagtacaaaa gatattccca
    18901 agtgtaaacc taacattagt tacagttata cttggattat ttatggttgt ttttgcactg
    18961 tatggtttta aagctatggc taaatttaat tacttagtta taccaccact tatgatatta
    19021 atggtgtggg gagtttttaa agctttttct acttatggag ttgaagctat ttataattat
    19081 actcctcaaa caactatgag tatggttgaa ggtcttaata ttgtagtagg tcttgttata
    19141 gttggtgcaa ttatatcacc tgaccagtta agatatacga gacgagtaaa agacatttgg
    19201 attatcagtt ttttaggtct agggattatt tcattattcc aacaagttgc agctggtgta
    19261 atgtctatgg gagcacctac ttgggatata acagaagtat tggctaattt aggttttgga
    19321 tgggtagcgt ttgttatttt aatacttgca tcttggtcta caaacgtatc aaatgcttat
    19381 tctggtggat tagcattaaa aactattttt ccaaatgtaa aaagaaatgt tttgacttta
    19441 gttgcaggtc taataggtac aataatagca gctactggta taatatttaa atttcagtca
    19501 tttttatctt tcttgggaat cgcagttcct gcaatagcag gaattatgtg gtgtgagtat
    19561 tattttatac aaggaagaac ttataagcat agagaaggaa taaattggat tgcagtaata
    19621 agttggttaa taggttttgc agcgtcgtat tatagttcaa aaataaattt cttaatacct
    19681 ccgataaatg gaattgtagt gagtatggtt atttattata tattaatgaa ttgttttgga
    19741 atcaaagata aataaagggg gcaattacat gggtcgtaag gtgaaaatag gtataattca
    19801 acaacacagt gtacttggaa atgttaaaaa aaatatagaa aaagcagtag agatgataga
    19861 tgacttagga aaacaagggg cagatataat ttgtttacca gaactatttg ctacaggata
    19921 taatttagag tctttaggtg gagttaaaac attagaatta ataagagaac ataataagta
    19981 catagaggaa tcaatgtcag aagctgctaa aagaaataat gtatacctga tatctccata
    20041 tggaacctta gaaaaagggt ctacacatgt ttataattca gcagttatat ttgatagaaa
    20101 aggtaagatt atgggagaat actgtaaaaa tcatctgtgg tcattagaag cagtatactt
    20161 taaaggaggg gaaaaagtag aggtatatga tgctgatttt ggtagatttg gtgtaatgat
    20221 atgttatgat gcaggttttc cagaagtatc cagagaattg acattaaaag gttctgaaat
    20281 aatatttata ccatctgcat ggagaataca agatgaagat atgtgggatt taaatgtatc
    20341 tcaaagagct ttagagaaca ctgtatatac agtaggtgta aatttagtaa gtaatgactc
    20401 taatttaata ctatttggaa agagtaaaat atgcaatcct agaggtactg taataactca
    20461 attagataca tacagggaaa aatatgtatt atcagagatt gatttagatg aaataaaaaa
    20521 gtatagggaa gatatcccct atttgaaaga cagaaaaagt agctataaca tataattcta
    20581 tactataata caagttcaat ataaaatgat aaaaagagga tgtatcaata ttaagattaa
    20641 atttattata ctttgatata tcctctttaa tattatcaac tttgatttaa atatttttaa
    20701 aatagttgat aagaaagttt ttgaacaaca acacagcttt agattcatag ttttcgctaa
    20761 accatgaaag atttaaatat cttttaaatt caatatcttt gatatgtaac aacttaatct
    20821 cagggtcttg agataatccc catgattttc cacatataaa tccaactcct tgaagtgatt
    20881 ttataagagc ataaattgta tatggtgaat cagactcaaa tgctattttg ggtttgaaat
    20941 tagctgattc gcacaggata tcaattacct ctctataatt ctcacccttc gttataacta
    21001 taaagttttc atctgaaact tcgcttagat atacttcatc ctttaatgat aaaggatggt
    21061 ttattgaaac tcctaatagt atttcttcgc atgttaaagt tatgctattt tctgagttta
    21121 gctttgtaaa tgaagaagat atgtacaaat caaaatcact ttttttataa gatgatggca
    21181 aagtatgtga cacattaaaa gtaatattgg gatatagttt tctgaaatta ctcaaaagtg
    21241 atggtaacac attagccgct gcaggagata atatctttac ttctcctgaa ttttccaaag
    21301 aagtgtcttg taactccttt tttgaacttt ctactaaatc taaaatgcta tctactcttt
    21361 ttagaaacaa tcttccatac tcatttaaaa caatatatct tccttttctg tcaaataact
    21421 gaactccaag ttctttttct aaggaagata tagttttgct taaagctggc tgtgctatat
    21481 ttaacttgtg tgatgctttt gttatgtgct ccattctagc aacagtttga aaatacttaa
    21541 gatgcaataa atccatagta taaaatacac ctcttttaat atgacttgag ttatatcaat
    21601 tttataatca actccacatt atacattata atataaagtt tatataataa actacaatat
    21661 attaaaaagt tatttaaatt gttatttata ttttgtacat aatctaatta aaaaaagtaa
    21721 ctttaaatgg ttaactaagg aaatattgtt acaaacttta gttatataaa aaattcgttt
    21781 gatgagcaaa gtattaatgt caagtaagaa taaaagctta ttagataaga aaaataatat
    21841 tttataataa tgatgttact taaattatta tgttatacta ttttaaatag gaaacattta
    21901 gatactataa ttttaggggg agtcaagatg aaattaacta aatcaatatc atcaatgctg
    21961 tgcttatctc tagttttaag cttatcacca gtagcatatg caaatgaaat aagtagaaca
    22021 acagttgaga atactttagt aggtcaggat agatatcaaa ctgctgttga agtaagtaaa
    22081 aaaggatgga gtagtgcaaa tgaggctgta gttgtaaata gtgaatctat tgtagatgca
    22141 ttagctgtaa caccatttgc taaattaaaa aatgctccta tattattgac agaaaaaaat
    22201 aatctaaatt cacaaactga gaaagaatta aaaagattag gagttaaaaa agtttatata
    22261 attggtctat ctagttctgt atcaaatgat gtgcaaaaac agttagaatc taataattta
    22321 actactgata gagttggtgg tagtgataga taccaaacag ctttgagtat agctaaaaaa
    22381 atagaaggat taaaagatat atcagaaata gctgtagtaa atgggtacac aggtcttgca
    22441 gatgcagtta gtatagcttc tgtagctgct actaatggaa tggttatact tccagtatct
    22501 gatgcatctg gtatatctag ctttaaagat tttatagaat ctaagaatat aaataaatca
    22561 tacataatag gctctactaa tgctgtatca gataaaataa aacaaagttt acctaattca
    22621 gaaagaatag gtggagcaga tagaaatgaa actaatggta aagtaataga aaagttttat
    22681 acatctaata aattaaacaa tgtatttgtg gctaaggatg gaatgaaaaa tcaaaatcaa
    22741 cttatagacg ctttagcagt aggagtacta gcatcaaaag aaaattctcc tgtactaatc
    22801 gtaggagaac aattaagtgc aacacaaaag agtgtatttt cgaataaaaa tgctacctct
    22861 ataactcaag ttggtagtgg aggaaatgaa aatgcattta aagaattaaa agatttacag
    22921 gcaaatagta acaataagag agtaatgtat gtaactaata cagataaggt aaatataaga
    22981 aatgatgcta caatagaagc ttctgttata ggatatctaa ataatggtga tgaagtagaa
    23041 gttttagatg tgttaaaaac tggatgggta gaaataaaat acaatgaagg tattggatat
    23101 gttagtgggt cttatttgac aaataataag cctgataata gtaatgaaaa tataaaaata
    23161 aagtatgtaa aagaaaaaga tggtctaaat gttaggaaag gaccaagtac agaagatgaa
    23221 aaaataggtc acctttcata tggaagcaaa gtagaaacaa tagaaatgtt tgctactgga
    23281 tgggtaaaaa taaagtataa tggtggatat ggttatgtaa gtaatgatta cttatctgat
    23341 acaccagtta tttaattata agtaacaata aaaaaactgc tttaatttgt aaagcagttt
    23401 ttttataaaa atttaagtct aataactatt tctattttga taccttaatc ctgggattta
    23461 ttattatgga tattatcaac atacaaacac tccaaatcca gtgtctaatt ccaaacttag
    23521 atattaataa attcagtcct gctatggtaa ataagcagta tttaattaca attaaaagtg
    23581 tatttataga aagccccttc atagaaagta tcctaaatcc aataatagac attctaagtc
    23641 ctataaatgc caataatata cctgcaatat cctgaattaa gtaatagtat tcaaatttca
    23701 tattcaatca actcttctct gagcagtatc aaatatttct aactcttcaa tttcatcatc
    23761 tgtgtatgta agcatagtaa aaccagttac accataaata aatgaaatta taggtgtaat
    23821 ccaacttaag aaacaatatg gaataaattc tagtgggctt acaccaagag tctgagcaca
    23881 gaaaacagca tttgaattcc atggtattaa tggaccacca agtgtagctg tatcttctat
    23941 aattctagat agattttgtg gttttaattt aaattctttg tatattggag acattagagt
    24001 tccgacaaat acagaagtga acatcattga tgaactaaat gcatttgcaa agtaacttac
    24061 tataaaagta gacccaacca atttagttct tgattttcct attttagtta taagaggttg
    24121 aagcagtact tctaagaatc cagttttttg gagaatacca gcaataacga aaactacaaa
    24181 tactagtaaa acggtttcag ccatactcat tattccacca cgatttaata gtttgtcggc
    24241 atagacaaat ccagtatcta tagtaaatcc tgatagcatg taatttaaaa catcacctat
    24301 tttttctcct tcttgaaata ctgctataat aagtcccatg atagctgaac ttagtataga
    24361 tataatgggt ggcttttgta gcaataaaag taataataaa aatattattg gaatcattgc
    24421 tactaaacca atatgaaagt ttgaatttaa tacatccttg atttgattta tttgaacata
    24481 gtctatagta ttatttgaat acttaaatcc aattactgta tacagaacta tacatattac
    24541 gtatgcaggt cctgtggtat aaaacatatg cttcatatgt gtaattacat ctgtcttaca
    24601 aactgctgca gctaagtttg tagaatctga tagaggtgac atcttatctc caaagaaagc
    24661 accagaaatg actgcaccag ctgttaaacc aagaggaata cccatactag taccaatact
    24721 catcattgct ataccagaag ttccaagagt cccccaagat gtaccagtag caacagaagt
    24781 taatgaacat acgattaatg ttgtaagcag aaaatattta ggggttatta ttgttagtcc
    24841 actatatact actgttggta ttgtaccagc agctatccaa gctgctatta gtacaccaac
    24901 agaaagtata attaagtttg attgaaaggc atctttacca acttcaaatc caaaagcttc
    24961 tatttcatca ttagtataac caagtttcat agctgcagga actactataa gccatgaaag
    25021 taaaaacatt gtagttatag aagcattaaa tacaactata ccaactgatg ttagagctat
    25081 tattgcaagc attactaaca aggaatatct aaatgaaggt atttttcttt ctgtattcat
    25141 tttcatagtg caaattctcc ttaaatattt ttagttaatt gcatttttta ttcttataag
    25201 agcttcttca agcatacttc ttggacaagc taagtttatt ctttgatacc cacttcctcc
    25261 aatgccaaag ctgtttcctt gatttagagc aactttacct ttttgtacaa gtatactttc
    25321 tagttcctca tcacttaatc caagtgcact aaagtctacc cataataaat aagtaccttc
    25381 tggttttcta actttaagtt ttggcatatt ttcatttata tattttatag caaaatctat
    25441 attagattct aaatattcta aaaatgattc tagccaagat tcaccattat tatatgaagc
    25501 ttcagttgca actaagctaa agcaattatt tctctttata tcaattctgg taaaggcatc
    25561 atctaacaat ttatagtctt tttcatcagg tagtattaca tatgatgatt gaagaccagc
    25621 tatattaaaa gttttagttg gagccataca agtaattgta tttttttcaa attctttaga
    25681 aatagatgcc ataggaatat gcttatgttt ttttaatata atgtcactat gtatttcatc
    25741 agatatgatt tttacattat gcttaagaca aatatctcct agttttttta attcatcttt
    25801 tgtccatact ctaccaactg gattatgagg attacaaagt atgaataatt ttacatcttt
    25861 aatcttgttt tcaatgtctt cataatccat tatgtagttt ccattttcta gtttttgtaa
    25921 tgggcttata attagttctc tattgttatt ttttacaaca ctattaaaag ggctgtaaac
    25981 tggttcttgt atcattattt tatcatttgc ttttgtgagt tcatttatta aaagacttat
    26041 agctgggata acacctggac tataaattaa ccactcactt tttattttcc agttatgtct
    26101 cctatctagc cagtttacta tagattcatt gtaagaatct ggtcttgttg tgtagccata
    26161 aatctcttgt tctagtctat tttttaagga atcaattata caaggtgcag ccttaaaatc
    26221 catgtcagcc acccacatag gaagtaaatc attagttcca tacttttttt ccatttctga
    26281 ccatttagat gaaaaattat tgcttctatc aacaatctca ttaaaattat aattcattgt
    26341 aaatacctcc agtaatttta attttatgtt aataatatta agcaaacaac gtgccaatat
    26401 tgataataaa aaatatttat tcacaagtta atatttaata ttaagtaatt tcagagcata
    26461 gataagataa aaatattaat tatacttaaa actttgtgga aaaggttatt tctaataaat
    26521 ttttaaatat atgaaaatgt aattaaatag gttaaatagg tttaactgtt taacttgtta
    26581 gacctattta tattttttag aaattctact ccttttgatg ttataattga acctccacga
    26641 ccaacaagta tgtctacaag cccaaagttt tgtagttcta aaagcatatt tctaatctgt
    26701 tgttctgtca aaaatctatt ttcctctaaa gctattttac ataagctttt tctacctatt
    26761 ctttctttta aatcataagc cttttttaaa ttatccaata taaatatgta ttcatctagt
    26821 gaccttttaa aattatagtc gtatttcatg atgtttttgt ctttgccaat gttgaattga
    26881 tactttttta tattatcact tactttatta caaacggttc tactataatt tgaatctata
    26941 gtatctaata tatattcagg taaatcacat atttctataa tatctttttc caagtaacag
    27001 aagtattctc ctaagtttct taattctctt acatttcctt cccatctata cattttaaag
    27061 atttctttta cttcctcact tagaataaaa ttacatggaa tatcatattt taatgaacca
    27121 aaaatttcaa atatatcagc aggtctttcc ctaagtggat gtattttaag gggaagaaca
    27181 ttcaacctaa aatataaatc tcttctaaac atatttttag atacaagttc ttttaaattt
    27241 ctattagtag ctgcaattat tcttacatca atgtcaatga cattattaga accaatacgt
    27301 cgtacttgtt tttcttgtat gactctaagt aatttagatt gagaatttaa atccatttct
    27361 ccaatttcgt ctaaaaatat agttccattg ttggctaatt caaataaacc aattttccca
    27421 ccttttttag caccagtaaa agccccttca tcatagccaa ataattcact ttgcagtaga
    27481 ttttcttgaa aagtactaca atttactgcg acaaaaggac catcttttct cctagaagca
    27541 ctatgaatgg attgagcaaa taattcttta ccagtaccac tttcaccaat tataaggata
    27601 gatgaatttg attgagccat tttattagca attttttttg tattaatagt ttgtatacta
    27661 gaacctaata tgtcatcaaa tgtgtattta ctgatattac cagagtttac tagttgtgct
    27721 cttaatttag cttgcttttt ttctaattga gaaaactttg tcatctttag tataaatcca
    27781 tcaaatacat ttaattgtat atgtttaatc tctaaattta tatcaatatg atttatttta
    27841 atcaatttct caaaaaatgg agttttattg gtcaatatgc tttgaaaatt gatgtctttt
    27901 atgcaatcac caacaaatga gtcaatcatt tcatttgcat ttatagacaa aatttttcta
    27961 gccatatgat tatagaattg aattattcca tcgttatttg tgcatataat tccatcatca
    28021 attatagata gcaacaaatc aaattgtctt tcaaacttat ttgcatctaa caataactca
    28081 cctgtactat aacttgtagg aattattttt tctacgtatt tttttattag gtcatctttt
    28141 attagatgtt ttaatttggt ttttgtagca atttcaacaa tacaacttaa atctattatt
    28201 ctgtatttta aatctataac ttcacaattt ttaaacttag gcaagatttt ttcgccagga
    28261 gttaggatta cagcatctgt gggagtaaac tcaatctctg gatagcaggg caggatattt
    28321 atattgtcta ttcctaatct atgtattaaa gaaattgttt ctattgccat atctttactt
    28381 aagttatata cataaataat tttatctttt tctaatttgg atatcatatc aatactgttc
    28441 ttttcaaatg tcaacttagg aacaatgatt tgagcatcat agtgagataa ttttactatt
    28501 tcatcatatt ttaaataagc agataggagt ataagttttt ctttaaaaaa ctttaaattt
    28561 ccctcttcaa atgagtataa atttatcttt agattatcac ctaagaattg ccttatttga
    28621 ttttcataaa tttctccagc gtcttttttt aaacttacaa tagctaattc catttgtttc
    28681 attttaacct ctcatacaaa tttgacttat tttagattac ataataatta aattagatta
    28741 aataatatta tttaattatt attataaatt tattatagac tacacattga agtaaaagaa
    28801 gtagctaaaa ttattccttt tatttttgtt ttttgtatct atttggtata atagtattag
    28861 agcgtataat aatttaggca aaatttttta aggaagacta gaggagaata taaaatgaaa
    28921 aaatgtcttt actgtaatag ggatataaag tcaccaaata ataaattagc tataaaatat
    28981 gatgacaata tgaatatata tccatgtcgt gcagaatgta aggaaaaaat tgaagaatat
    29041 atagcaaaaa aacctacata taagtttata aatatattag aggttctttt aggtgtgggc
    29101 ggaatattct gctttttgag taaatggact attgcagccc aagttgtact tggaattgat
    29161 gcactggtta tatttttatt cccattggca ggatttaaaa tgaatggaaa gttaagtatg
    29221 gaacaaacta agaatcaaag taggtctatt gcaatatcaa ttttggcatt tatagtaata
    29281 ataactgtat tatattttaa acaagttggt aagtagagca taattgtata agacatcatt
    29341 agagtatgag gtgagtttat ggaagaaaga aaattagcac caaacaatga gagggaagct
    29401 ctcataaaaa gattaaaaag aatagaaggt caagttaagg gtatacaaaa gatggtggaa
    29461 caagaacgtt attgtgttga tatattggtt caaatatctg ctataaggtc tgctataaat
    29521 agagtaggca caattatctt agagaatcat ataaaaggat gtgtagcaga aagtattaaa
    29581 catgatgatg ctgataaaac tgaagagatg ataaaagagc ttatggatac tataaataaa
    29641 tttacaaaat aaggaggcgg ttagttatga atcaacaagg atttattatg gaaattgttg
    29701 atgatagaac tgcaaagtta aaaatgcaaa gacattcagc ttgtgctgct tgtggaaaat
    29761 gtgctactac aaattcagca gagtcaaaag aaatattagt agaagtagac aacacaattg
    29821 gtgcaaaagt tggtgaccat gtagaagtga gtatggataa tatgaatgta ttaaaagcag
    29881 ctgtaatggc ttatataata cctcttatag cacttcttgt aggaacaata gggacttatt
    29941 atatattggg ggcaattgga atgacaactg gagttgaagc cataagtgga ttagttggaa
    30001 tttgtcttac aataatctgt tatttatact taaagaagaa tgacaaaaaa tttagagaca
    30061 gtagagaatt tataccagta ataacaagaa tattaattga cctttaagat aattataatt
    30121 aaaaaatagc aatgtacttt ttaaataaat actcaatacg tatttgtaga gtttaagtac
    30181 attgctattt ttatattttt attttgattt tctgtaagga ataaagtttt ttctgatttt
    30241 taaaagattc aatgttctta caaaagaagt tacaactaat acaccaagtg ctattgcagc
    30301 acttagaaat agcgcatctg taccttttga catagccaaa gaataatttt tctgaatcaa
    30361 agacaacatt gtattatata gcccaattcc tggtattaga ggaagaatac ctggaattac
    30421 gaacacaata gctggttgct ttagttttct tgctaaagtc tcactgcacg ctgagaccaa
    30481 agcagcagcg ataaaacctg caaaaactgc atttgtagta aaattaaata aataaacata
    30541 tacaatccaa ccaattccgc cagttactcc agctggaaga agtagatata gtggagcatt
    30601 aaagaaaaca gcaaatccag cagttgcaac acctgaaaat aaaaaatgca aaatcataga
    30661 catatcagtc attagaaagg acctcctatt ctataccatg tatcaaggac aaaaccaact
    30721 ccagaagcaa ttgcaataat aatcatagca gcatcaaaag cacgagaaat tcctgatatt
    30781 aaattccctg atattaaatc tctaatagct tttataaaag caactcctgg gagtagtggc
    30841 attatagcgc cgactataag cattttaggg tcatctaaaa tgcctatttc aactagtaga
    30901 actcctgaaa gtgcaattaa aaaagaagat actaaacagg aaaatgcaga tattgcactt
    30961 atcttcatcg ttttatcata agtaattgca gcaaagattg ctattataaa cgtaagtata
    31021 aaatttaata cataattccc tccaagcaaa caagcaaaac aagcagatgc aattcctgta
    31081 caagagtaaa ataaccataa aggataaggt tttacatctt ggatttcata aagacgtgca
    31141 atggcattat caatatcata ctctttgtca ctaacaaatt ctcgagaaaa actgtttaat
    31201 aaagaaatct tatttaagtt tatacctctt gattgaatcg ttttcataaa cgaaaagcca
    31261 tcaaatttct catctgaaat aattattact gtaggagttg taaaaatatt tacatgataa
    31321 aaccctcttg acctgcatat tctaaggaca ctgtcttcaa ccctagatgt ttcagctcca
    31381 ttttttatca tcagttcccc tacaaataga gctagtttta gaatattttt cttatattca
    31441 agttcctcat tttgattcat aaatacacct ccaaattaaa aaacgtaata ttgaaattat
    31501 atcaaatttt taagtaatat tccttaatat ctatacaaat atattatctt ttttttgttt
    31561 caaaatagtc acatttaaat tatatccaat taaaagaatt agacaatatt atttattata
    31621 ttttaactta aaaataaaga aagtaactat gttaaatatg gaaaaatggc aaaacacttg
    31681 actattaatt ggtaaaggac tataataata aattatcata ttgataaaaa cgaaaattat
    31741 gaaatgtctg taaaaataaa atttaaataa taactaggag gagtaatatg tttgagaact
    31801 tgaaaaaagc ggaccctgag atttatgaaa gtatgaaaag agagttaaaa agacaacaaa
    31861 gaaatattga attaatagca tcagaaaaca tagtatcagt tccagtaatg gaaactatgg
    31921 gaagtcatct tacaaataag tatgcagaag gttactcagg caaaagatat tatggtggat
    31981 gtgaatacat agatgaagtt gaaactcttg caatagatag aatcaaaaaa atatttggag
    32041 cagaacatgc taatgttcaa cctcactctg gagcaaatgc aaatattggt gtatattttg
    32101 ctatgttaaa accaggtgat gttgttatgg gaatgaattt atctcaaggt ggacatttaa
    32161 ctcatggtgc tccagttaat atttctggtc aatattataa attttatgaa tatggtatag
    32221 ataaagacag tggacttata gattttgatg aagttagaaa gatagcacat gaagtaaaac
    32281 ctaaaatgat agttgcagga gcaagtgcat atcctagaga aatagatttt aaaaagttta
    32341 gagagatagc tgatgaggtt ggagcattgc ttatggtaga tatggctcat atagcaggtc
    32401 ttgtggctgc tggtcttcac caaaatccat gtgaagtggc tgattttgtt acaacaacaa
    32461 ctcacaaaac tttaagagga cctcgagggg gtgttattct ttgtaaagaa aaatatgcta
    32521 aagacataga caaagcaata ttccctggta ttcaaggtgg acctcttgaa catataattg
    32581 cttctaaggc agtttgcttt aaagaagctt taagtgatga gtttaaagaa tatcaggtac
    32641 aagttgctaa aaatgcaaaa gccttagctg aagaacttat taaaagagat tttaaattga
    32701 tttctggagg tacagataat catttaatac tattagattt gactaataaa aatataactg
    32761 gtaaagcagc agaaaagaga ttggatgatg cttatataac agctaataaa aatacaattc
    32821 catttgaccc aaatggtgct cttattacaa gtggaataag acttggtact ccagctgtaa
    32881 ctactagagg tatgaaagaa gaagatatgg caataatcgc tgaggctata gacctatgtt
    32941 taacttatga tgaagaatct aaggctagaa cattggttgt tggtttaact gaaaaatatc
    33001 ctttatatga agaatataat attatggatt aattataaag aacaactaaa taaaatacat
    33061 ttaaataatt acaatgattg tgtatgtatt tgaatatagt tagatataaa aaaggtgtct
    33121 caaaatgaac tttttagttt atgaggcact tttttgtatg gaatcgaaca tatttgtgtt
    33181 atttaaataa taaaaaatat ggttatctct atttttagat ggtctctttg tattttttaa
    33241 ttaaaacttt aagatttctt aagaattata ctaggttttt ctaaagattt aaagtctata
    33301 cttataagta tagtaatcat atgaaaagaa aagctttaac gaggagggaa tcttatgaag
    33361 gtattaattc ttacaggaaa atttggtatg ggtcattact cagcatcaaa ttctttaagt
    33421 gaagatataa aagcaaaatt tgataattca gaaataataa ttaaagatat atttgagtac
    33481 attatgccta actattcaga taaaatgtac aagacttttt ctattcttgt aaatcgggga
    33541 agtagtcttt ataatttatt ttataaatgt gctgaaaatg gaaagaaaga tataaaattt
    33601 actttttcag attatttttt aaataaatta gatacattac ttcatgaagt acaaccaaca
    33661 gtagttattt caacttttcc attttgttct caattagtat caagatataa ggaaaaatat
    33721 aactcaaatc ttcctttaat aacatgtata actgatataa gtagtcactc agaatggatt
    33781 agtaaaaata cagactgtta tttagtagct agtaaatcta ctaaggaaga acttgttttt
    33841 aaaggaatag atgaatctaa gattaaagtt aatggtattc cagtaaaaaa agaatttaaa
    33901 agaatagaac atgtaaatca ttcaactaaa aaaaatattc ttataatggg tggaggatta
    33961 ggattactgc ctaaatcaga acaattttac aaagaattaa atagtttaga aggagtaaaa
    34021 actactgtaa taactggtaa taataaaaaa atgtactata aactatatgg tagatatgaa
    34081 aatatagagg tagtaggtta caccaatgaa gtatataaat atatgaaaga ttctgacctt
    34141 attatttcta aaccaggtgg aataacacta tttgaaacaa tttattcaga acttccaata
    34201 ttggcattta atccattttt acaacaagag atagataatg ctagttttat attaaataat
    34261 gaaattggga gaatacttgg taaaaataaa aaatactatg tagatgagat aaaagattta
    34321 atttatgatg atgctactct taaagaaatg agcagtaaca tgaaagaatt aaaaaaacaa
    34381 tttgataata ataccttaga gaatatttta ttttcacttg atgaacaagg agcgtgtaga
    34441 gaatgtatgt agtaggttta attatcgttg ttgcattgat ttttttagtc cattcaatta
    34501 tacctacata ctataataaa ctattaaata aagaggtatt aaaaaatatg gctggagaaa
    34561 atgaaattgc acttacattt gatgatggtc cagataagag atatacagaa aaattactag
    34621 atgtgttaaa agaaaatgat atacaagcta tgttttttgt agtagcaaag aatgctgaaa
    34681 aagagcctga aattataaaa agaatgttga gagaaaatca tatagttggt ttacattcat
    34741 tggaacacag aaatgcatgg ctttatagtt atagttatgt taaaaaagat tttattgaaa
    34801 gtacaaatat aatgaaaaat ttaggtgtag atgtaaacta ctatcgtcca ccatggggtc
    34861 atactaatat attttcaaat tcatttgtta aaaaatataa tctaaaaatg actttgtggg
    34921 atgtaatggc agaagattgg gagaaagata gtacagtaga cattattata aacaagttaa
    34981 tgagtagaac aaaagaaaat tctataattt gtttacatga tgcaggtgaa aattcaggtg
    35041 gtgcagtagg tgcacctgag cgtactattg aagctttaaa gatagctatt ccaaaactta
    35101 aagccagtgg tttaaagttc gtaacaccag aaaggatgta gttatgataa gtaaaactga
    35161 aaagaaaaat aaatgcctag gtagtgtagc ttttttagtt ttactaatgg gcataacagg
    35221 atattttgtt tttagagggc agtcagttga atcattgata aaatcattaa aaggtgcaag
    35281 ccctatgttt atactaattg gatttgcaat gatgtttata tatgttgcct gtgaaggtat
    35341 aaatatatac ttaggtatga aagctttaaa ccaaaagact actcttttaa aatgtatggg
    35401 atatgctttt attggatttt attttagttc tattacacct tcagcatcag gtggtcaacc
    35461 agcacaagtt tattatatga aaaaagacga tataaatata tcatattctt cacttatact
    35521 attagtcatt gttgttattc accaagtagt tatactggca tatagtggaa taatgttcat
    35581 tatggaacgt gagtttatat taaataatgt aagtggtatg aacattttac taatatatgg
    35641 tgtaataaca aatgttgctc ttgtcattgg agtaattgca attatatttt caaaaaaact
    35701 tgtaaacaat tttataatat caataacaaa tttattaggt aagttaagaa taataaaaga
    35761 tgttgaaagt tcaagaaaag ttataatatc tcaaattgaa gagtatgtta aaggtgctca
    35821 atatataaag cagaatccaa aacttgtagt ccaaatttta gtcataacta ttgtacaaat
    35881 aacagctatg tttttagttc ctttctttgt atacaaagct tttcatctat caacatatac
    35941 tgtatttgag atattagcga tacaatcctt gcttaatatt gctgtttctt cattaccatt
    36001 gccaggggct gttggagctt ctgaaaatag ttttatgaca ttatttaaga tatttttccc
    36061 tggtcactta ttagttccgg caatgttact tagtagggga ataagttttt atgcatttgt
    36121 agctataagt ggattgatat gtatagtagt acatgtaaaa tcttctgaaa aagtaaaagc
    36181 agtgaaaaaa gttgcttatg taagataata ttatatagat tatttttatt aatatgtcaa
    36241 tttgtgtgta tattttaatt aagctttaaa catatttaca ggagtagaaa ctattaaaac
    36301 gtgtgacatt gctaagcttt tgctaataaa gtataatatt ttatatagtt tgaaatattt
    36361 aagaaatata gcaaaaaaag gagcttggtg atgaataaag agattccaaa aaaaatttta
    36421 gtagctgatg ataatcctga gattagggaa atcgtagaaa tacttttaac tggtgaaggt
    36481 tatgaagtta ttatggcaac gaatggagaa gaagctgtaa acttagtaga tagtacgatt
    36541 gatttgatta ttttggatgt tgtaatgcct gtaaaaacag gatttgttgc atgtaatgaa
    36601 attagagaaa aaacgacagc accaatatta tttttaactg caaaaactca agactctgat
    36661 aaagttattg gattttcagc aggaggagat gactatttat caaagccttt ttcatattct
    36721 gaactaattt caagagttaa gtctctactt agacgttatt atatatacca gggaaaggaa
    36781 aaggaaagag agccaaatat attaaaaaca aaagagttat gtgtcaattt agatactcaa
    36841 gatgttacac taaatggaga acctgtgttt ttgacaacta tagaatatag tatattaatt
    36901 cttatgttga aaaatagaaa aaaagttttt tcgtctgaaa atttatatga aactatttgg
    36961 gatgagcagt atttttatac agcaaataat acaataatgg ttcatattag aaatttaaga
    37021 aaaaagttag aaaaagacca aaaaaatcca caatatataa aaaccgcatg gggaaagggg
    37081 tattatattg attaacaaaa ttaagccatc taagttggga gttatactat tgatatatgt
    37141 agtaatctca gctgcagtgg ctttcatttt aaatatacca ttttactctg ctgttgaatc
    37201 tatagtaaaa gatgtatcag aagggaaagt atattttaaa agagaagtaa atcaacttat
    37261 ggataatttt caaacttatg tgaataacaa tggtataaga gcagatgatg gagatgatat
    37321 agcaaaatgg aatagtgata attggtttgt ttctatgaag atatataaag gaaataaggt
    37381 tttttatgat acattatact atcctaatga agtacctgat aagagtgagg aaaatgagtt
    37441 ttatagcagt cccatggcta gaaactatga gatacaattt tctgatatta aagctaatat
    37501 agttgtagta gctttattta gatttagatt tcaaaatttt atagaagcaa tttctattac
    37561 atttatggca cttacattta ttataacatt tttactgttg tttagtagaa agataaagta
    37621 cctaaggaaa atagaaatgg gtataaagat agtagagagt ggcagtttaa agtatagaat
    37681 accagtaaaa ggtaatgatg aattatcatc acttgcatct agtattaatg agatgagtca
    37741 tacattggag aatcaactta taaaagaaag ggagatgaag aataaaaata aagatatagt
    37801 aacttcaata tcacatgatg ttagaactcc attaacgtca gtaatttgtt atttagattt
    37861 gattaaagac cataaataca atagtcctga gcaattggaa caatacataa aaaatgtaag
    37921 gtctaaagca tatcaaataa aagatttaac agatgacctt tttacgcatt ttgttaattc
    37981 tggagaggaa gtttcaaaag ggtatgaaaa aataaatgct aatgaattta tttttcaatt
    38041 acttttagat agttcatata cattggagga gaaaggattt catataacaa tagaaaatga
    38101 actttataac caatatcata tttatgtaga tgttacacaa tttagaagga tatttgataa
    38161 tttatgttct aatataataa aatatgctag gaaagataag cctatagtat ttttaattaa
    38221 agtagaggat tctaaattac taattataca aaaaaataga gtaagtaatt tttctaagaa
    38281 tgtagaaagt tttggaattg gtataaagaa ttgtgagaaa atagttgcat atcataatgg
    38341 aagcataaat gtaaattcag atgataaaga atttgctatt gaaatatcta ttccagcaaa
    38401 agaatcataa aaatttaaat tatatattgt gtaattgcta ttatatattg tgtaattgct
    38461 tatgtaaaat tctatgaagc aggaagcatg tgactttagt tatgggatgt tcaatattgt
    38521 gtacctctag gcaagtaaca agtttactta caagaccata taatattatt atcttaaaaa
    38581 aaggggacat aataatatgg ttttgacagg agcacattat atttacattc tatttatggt
    38641 aattatatta attactatga ttatgaaaaa ggatacaata gtaccatgta tattaggtgt
    38701 tttttttatg gggttgttct ttgaaaaaaa catttttggt gctataacag cagtgtttaa
    38761 ctcttttatt atatctttaa atgagttggg tccaattatc ttgattatag ctattatggt
    38821 tgcattatct aaagccctag aagccaataa tgctatacag tatatggtga gaccattttc
    38881 gagagttata aaaaattcta atacagcatt ttttgtaact ggatttgtta tgttagttct
    38941 ttcttggttt ttctggccaa ctccagctgt tgccttagtt ggagctgtat ttttacctgt
    39001 tgctatgaga gctgggctac cagcaattgg tgttgcagta gcattaaatt tatttggtca
    39061 tggtcttgcc ttgtctacag actttgttat tcaaggagct ccaagtataa cagctggtgc
    39121 agcaggtgtt gcagtatcat atgttataaa tgatggtatg attttgtttt gggtgatggg
    39181 aatcgtaacc atatctatgg cattttatac attaaaaaga gatattaaca aaggaatgtt
    39241 tagagaagaa ctaaaaggtt ttgaaagtga agaagtagaa gagttcaatg gaaaatctaa
    39301 aatagcaact attttagtag ctctgggatt tcttgctgat ataattgcta tgtatatatt
    39361 tgacctaaaa ggaggagatg catcagctct tttgggtgga acagcagtat ttttaataat
    39421 aattataaat gttataaatt ttggcaaaga tagtcttgaa aatgtatgtg agaatataat
    39481 tgatggtttt gtgtttggga taaaaatatt tggagcaatt ataccaatag cagcattttt
    39541 ctatatgggt gaagttgcac cattgacagg tgtatttgga aaagtattag caccaggttc
    39601 acaaggttta ttatcagata taggcatagc tctttctcaa acaataccac ttaataaatt
    39661 tgccgtatca ggtatagaaa ctgtagtggg agcaataact gggcttgatg gttctggatt
    39721 ttctgggatt tcattagttg gttcacttgc ctctgtattt ggaactgcta taaatgcaag
    39781 tgttggtgca ctagctgcat taggacaaat cagtggtata tgggtaggtg gaggctgtct
    39841 agttccttgg ggtcttattt cagcagcggc aatttgtgga gttagtccaa tagaattggc
    39901 aaagcgaaac tttgtcccag ttataaccgg attggttgta acaaccatag tagcaatgtt
    39961 tattatttaa taaatcgaat aaatctttaa ttgtataaat taaaaataga tgtgtagcta
    40021 taatttatta taattgtttt actaattcta agccatacat ctatttttat tgatattttt
    40081 attagtattc tttaataaaa taatattttt cattatacta tacataacat ctaaatataa
    40141 catctaaaat actgttatct atatttaata tcttgccaaa ttttttgatg ttttattgcc
    40201 ctgtcccacc aacatatata agctatcaca agtttttacc tatactatca ccaaacaaaa
    40261 attctaattt taatttatta ttttataacc tatattatat taactatatt agtttgtaga
    40321 ctttagatgt aattataaat attaatactc caagagttca aattcatatc ctagttttct
    40381 tgcatttgat ataaaatcat ttaaaatttc tgtactagtt ttggaaactg catgtagtaa
    40441 caagatagaa ccatcatgta gattatccat tattttttgc gttgcttctt catgtgatgg
    40501 ttgtttatca gtatcccagt ctctgtatgc aaaactccaa aatacagtct tgtatcctaa
    40561 atttttagtc attgccaagc ttttttctga gtattttccc ataggaggtc taaaaaattt
    40621 aaccatatct ttcccagtta catctttata taacttttca acatcatata attcgtcatt
    40681 aaagtttttt agattgcttg tttttgttgg catagatgga tgggttttac tatgatttcc
    40741 aactatatgt ccctcagaaa ccattctttt tactaaatct ttattttctt ttatatatgg
    40801 agctgtaaca aaaaaaactg ctttaacctg attttgtttt agagtgtcga gtatttttgt
    40861 agtgtatcca ttttcataac cttcatcaaa tgtaagatat agtgtttttt gaccatcttt
    40921 tgtaggtcca ttgtataggg catcatagtc agaaaattta aattcaatgt ccgtatttac
    40981 ttctggtgtt ttatgcttat tgtttggtat ataaaaccaa tcaagagtag tgttatctaa
    41041 agaagataca tctaatttat tattatcatt attagtagtg gcttttgatg gtttatctgt
    41101 tccgtctgaa actattacat tggaagtatc tttaccacta tctatttttt ccttatcttc
    41161 ttgtaactgt gtttccttat tttgattttc gttttgattg ttttgtgaat ttgaacatcc
    41221 aacaataaaa aaaatagaaa tagaaagtag tgttaaataa tgcaatactt ttctaaacat
    41281 tttgaagctc ctttctaaat taataataat tgcatataat aataattata tgattaatta
    41341 caattgcata tagtattatt ataattggaa attactatta ataatagtta tatctttaaa
    41401 aataaggtca caatagtatg acaaagggtg aataatcaat aaatttaaaa aaaaatgaaa
    41461 aaaatagttg accatattat gagaagatgt tattataata aatgtgctca acaagaagta
    41521 acaaaataac aagcacaaag aagttaattg aat
//
LOCUS       DAEHWO010000031        41201 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEHWO010000031 DAEHWO010000000
VERSION     DAEHWO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41201
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.031"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(310..1377)
                     /gene="rsgA"
                     /locus_tag="KNP54_001946"
     CDS             complement(310..1377)
                     /gene="rsgA"
                     /locus_tag="KNP54_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBF0892848.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            complement(1374..1775)
                     /locus_tag="KNP54_001947"
     CDS             complement(1374..1775)
                     /locus_tag="KNP54_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBF0892849.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      2572..2668
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            2722..2898
                     /locus_tag="KNP54_001948"
     CDS             2722..2898
                     /locus_tag="KNP54_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892850.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            3308..3946
                     /locus_tag="KNP54_001949"
     CDS             3308..3946
                     /locus_tag="KNP54_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892851.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(4419..5777)
                     /gene="rlmD"
                     /locus_tag="KNP54_001950"
     CDS             complement(4419..5777)
                     /gene="rlmD"
                     /locus_tag="KNP54_001950"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBF0892852.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(5952..7712)
                     /gene="pyk"
                     /locus_tag="KNP54_001951"
     CDS             complement(5952..7712)
                     /gene="pyk"
                     /locus_tag="KNP54_001951"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBF0892853.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(7764..8723)
                     /gene="pfkA"
                     /locus_tag="KNP54_001952"
     CDS             complement(7764..8723)
                     /gene="pfkA"
                     /locus_tag="KNP54_001952"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBF0892854.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(8932..12501)
                     /locus_tag="KNP54_001953"
     CDS             complement(8932..12501)
                     /locus_tag="KNP54_001953"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBF0892855.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(12658..13605)
                     /gene="whiA"
                     /locus_tag="KNP54_001954"
     CDS             complement(12658..13605)
                     /gene="whiA"
                     /locus_tag="KNP54_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBF0892856.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(13622..14047)
                     /locus_tag="KNP54_001955"
     CDS             complement(13622..14047)
                     /locus_tag="KNP54_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBF0892857.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(14116..15222)
                     /locus_tag="KNP54_001956"
     CDS             complement(14116..15222)
                     /locus_tag="KNP54_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBF0892858.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(15234..16091)
                     /gene="rapZ"
                     /locus_tag="KNP54_001957"
     CDS             complement(15234..16091)
                     /gene="rapZ"
                     /locus_tag="KNP54_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBF0892859.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(16122..16835)
                     /locus_tag="KNP54_001958"
     CDS             complement(16122..16835)
                     /locus_tag="KNP54_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBF0892860.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(16839..17753)
                     /gene="murB"
                     /locus_tag="KNP54_001959"
     CDS             complement(16839..17753)
                     /gene="murB"
                     /locus_tag="KNP54_001959"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBF0892861.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(18026..18796)
                     /locus_tag="KNP54_001960"
     CDS             complement(18026..18796)
                     /locus_tag="KNP54_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBF0892862.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            19114..20595
                     /gene="cls"
                     /locus_tag="KNP54_001961"
     CDS             19114..20595
                     /gene="cls"
                     /locus_tag="KNP54_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBF0892863.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            20913..21410
                     /locus_tag="KNP54_001962"
     CDS             20913..21410
                     /locus_tag="KNP54_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBF0892864.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            21427..23313
                     /locus_tag="KNP54_001963"
     CDS             21427..23313
                     /locus_tag="KNP54_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBF0892865.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            23336..25117
                     /locus_tag="KNP54_001964"
     CDS             23336..25117
                     /locus_tag="KNP54_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBF0892866.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(25257..27053)
                     /locus_tag="KNP54_001965"
     CDS             complement(25257..27053)
                     /locus_tag="KNP54_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBF0892867.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENIILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(27265..28194)
                     /locus_tag="KNP54_001966"
     CDS             complement(27265..28194)
                     /locus_tag="KNP54_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBF0892868.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(28194..30011)
                     /gene="uvrC"
                     /locus_tag="KNP54_001967"
     CDS             complement(28194..30011)
                     /gene="uvrC"
                     /locus_tag="KNP54_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBF0892869.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKVLTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(30270..33095)
                     /gene="uvrA"
                     /locus_tag="KNP54_001968"
     CDS             complement(30270..33095)
                     /gene="uvrA"
                     /locus_tag="KNP54_001968"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBF0892870.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(33114..35084)
                     /gene="uvrB"
                     /locus_tag="KNP54_001969"
     CDS             complement(33114..35084)
                     /gene="uvrB"
                     /locus_tag="KNP54_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBF0892871.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(35271..36533)
                     /locus_tag="KNP54_001970"
     CDS             complement(35271..36533)
                     /locus_tag="KNP54_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBF0892872.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(36596..37900)
                     /locus_tag="KNP54_001971"
     CDS             complement(36596..37900)
                     /locus_tag="KNP54_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0892873.1"
                     /translation="MKLKRKLATGLAITLLLCSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(37931..38791)
                     /locus_tag="KNP54_001972"
     CDS             complement(37931..38791)
                     /locus_tag="KNP54_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBF0892874.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(38835..39704)
                     /locus_tag="KNP54_001973"
     CDS             complement(38835..39704)
                     /locus_tag="KNP54_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBF0892875.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(39688..40758)
                     /locus_tag="KNP54_001974"
     CDS             complement(39688..40758)
                     /locus_tag="KNP54_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892876.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        12975 a         7234 c         5091 g        15901 t
ORIGIN      
        1 agttttgctc ttaagaaaca tctctatcat acataagcat atactctatt atgtattagt
       61 ataaatatgc cttttcttat cttacataag acctctttat aaaggagcct atcgtaacaa
      121 atatgtatac attatcacat gtatatatca tcatataaaa aatcaaactt tattaaaaaa
      181 attaataaat tgctttaaat aataccacaa accaaatttg ccatcaaaat cacattaaag
      241 taacaaattg atggcaaatt taatatatta atagtatata gactcataga atgaacaaaa
      301 aaactacact tatcttctaa tcttcttatt tatttttgag atatttttaa atttcttttc
      361 tttttttgct aagtattcgc ttttattgtc tgcaaatact gcttcagttt taagcctacg
      421 ataggattcc catcttttag gcgaaagttc ttgatgagca atagcttccc agatagcaca
      481 gcctggttct gaggtgtgag tacaattacg aaaatgacat tttccgaaat aagcttctat
      541 atctgcaaaa cttttatcta aaccttctga aacatcccac attcccaact ctctcatacc
      601 tggtgtgtca ataacaatac caccacctga aattaaaaat agctctcgtc tagtcgtggc
      661 atgtcttcct ttatcatcat ctatgcgaat ttcctttgta tttaaaaatt ctccacccat
      721 cagacaatta attaatgaag attttccaac tcctgaagaa ccaagtaagg caacagtaca
      781 gcctggttta atatacttag aaatctgttt ataaccatct ggctctatag atgaggtaac
      841 aactacatct acacccaagg ctatagaatt aactacttgt aatttacgat gcacattgtc
      901 acataagtct gatttagtaa gtactactac tgggatagct ccactttccc atgttaaaga
      961 cagatacctc tccaatctat gaatgttaaa atccttattc agtgacatgc acaaaaaaac
     1021 aatgtcaata ttagctgcaa ccacctgctc ctcatttacc tttccagcag ccttacgcac
     1081 aaacaagctt tttctatgaa gcacatgatg aataatagca ttaccatttt tattattgca
     1141 acgatccaac ataacgaaat caccaactgt gggaaaatca gattgtatag tagcctcaaa
     1201 acgcagcttt cctgaaacct ctgcaaacag tacaccattt acacatacag cttgataaaa
     1261 gttcttttcc tgcgagataa tccgagcaag gtataaatca tgatattcca tactttgagt
     1321 aataaaattt ctatttagac catagtcttg taaattgatt tgtttcatac cattcattct
     1381 gtttcctcct tttccaactt ttcaatgatt ctttctagtg ggaaaggggg ctgtgccagt
     1441 ggttttaatg caattgacat taatttcact gaattatcat cagctgcaat acgattagaa
     1501 ctaagatgtc cacagcgtgt acaacgatga ataattgccc actcaccatt ttttctcacc
     1561 cacactccaa taggttccat attagcatca caatctgcag cacggtcacc aggaatgata
     1621 tctacatgaa gactatgtaa acaatgtgga caatgatttc tatgttgtgt accagctcct
     1681 tcaggaacta caaggcaacc acaatttttg caaataaagt tatccataca ggaattttcc
     1741 tgataataag ctcgttttct atttttataa ttcattttta tttcctccgt atcgtgtatt
     1801 ttctacaaaa aaagtccaca ggtatttata tctgcctttt tatgtggtat acatatttac
     1861 ctacacaaaa acagaaaacc cctgtggact agaaaattta gtatcttcta tttcaacata
     1921 attatattca aaataatact gtgtaaaatt aataaaagtg tagcagatta aagcccacta
     1981 caccacaatt taacaaagta atatgtaata ttattatttg ttgtctaatg ttagttatct
     2041 ataaaggcag agtaagacac aacaatcaaa tgtatcaaaa atacacttaa aaattctgat
     2101 taaacagaac ccatatgcgt ctccaactat ttatttgttg gttaccatta tatataactc
     2161 tgacatcagg caagacactc cttcactaat aattattatt gaaattttat cataaaatat
     2221 aagtatgttc aagtataatt taatatattc atatatttat gtttgtctca ttttcttatt
     2281 ctataaaatc tagtggtatt ttgaaattta atgttcacct agtattaata ataaaaatta
     2341 actgctatta tttgttttct cattttatgc ctgttgctca atttatctca cttaaattaa
     2401 taacaactgt cttttcatac aaaacctaca atcaagtttt tccatatatt ctacatgcat
     2461 agtctatttt ttttgatata aaataacgtt catatttgta aatttattta attttcaaat
     2521 aagtatattg aataataagc aattctattg tattattgta attgtagaat aaaactaaat
     2581 cggcaaaact agagaaattt agtgacgcaa agctataggg actaacgctt ataaaataaa
     2641 ctatgagtta tgtcagccag ttgccaaaaa gagatattct ttttgttttt atgaaagttt
     2701 tttaggggga taataatata tatgtttaga gataaaatgg atagatgtac acatatgttg
     2761 actgcttata ttggtagttc atatgattat tgtgatttta tagatacaca actagatgat
     2821 tttatactag agtacggaga aaatgtggta gaatcttgtt tgcatcaagt gatggtatta
     2881 gtaagtaagt ataattaaat agatttggtt ttctagagaa ccctttttag ttttatctac
     2941 tttaaatagc cttatgttag aaagctaatt aagatagatt tctagtattc ataattttat
     3001 tttttattta aaatacatat aataaagatg taaatttgta tcaaataata aatatgagaa
     3061 cttaaattct cttatctatg tgaaaataaa catctcttaa aatgaaattc tgtaaatata
     3121 aatgattttt tagtttgaag gattagatta acaaaattat aaatttgcaa ataagctata
     3181 ttaaaaaata taataatttt ttatataact tattctttta taacttttaa ttttaaaaga
     3241 ggagaatgta tataagagta ttcaatgtac tagaaaaaat caaaagaaat attagaagaa
     3301 atggatattg agtaatcaaa gaaaagattt tgatattaca aatgatatgt ttcaagaaag
     3361 cattcctatc acaacaaaaa ttattcttga agacatgcct tcaaatgatg aattaaatca
     3421 tgttttttca aaaggttgtg aacgaaaaat gaaaaagaga aaaattgtat taatcacact
     3481 actattaata ggtgttttgt tattaggaag tatcctatat aatctttttt taggaaaaac
     3541 agctaatatt tcaatgctaa aggaatcttg gaattttgat ataccaatac ctaacaaaga
     3601 aattgaagta tttgatactc aagatagtat taatggagat ggacaaagtt attttattca
     3661 aggattttct gaaaaaaatt tcaaaaaagt ttttaattta aaaggtggta tagttgtaag
     3721 caaagataat attaatgaaa tagaaaaata tattgataaa tttaaaagag attctgttaa
     3781 cattaataaa agtaataaaa ataaaattga agaagatttt aaaaaatata agttagaagt
     3841 taaaaaagat gataagtata tatataagag aaattatgag aactacgtag ttttaattat
     3901 aaaaaaagat gaacaaaaat tatacagttt aatatggaat cagtaggtac atatgtatta
     3961 ttaagaatta taaataataa aaataaattt tagtcaatat acaaaaacct tttaaattgt
     4021 ctggaaatca cctcttcatt tgttataaaa acatacaaca aatgaagagg tgattttatg
     4081 gttttaaaaa aaataattat aagtggatat gtgctttcac atgtttatca acatttgtaa
     4141 tgcctatatt tgctaatgaa ttataaaaat attaaataat attcaactat agattatgta
     4201 aattactcta tgaaaaaaat gagttgtata aaatctggct actgtagatt gactatttct
     4261 tttaaaatta caattataat aagttttata gaattaaaaa taaaacttta gagatttttg
     4321 ataacattgt agactaaatt tgccaccgaa atcgctttac agtggcaaat cggtggcaaa
     4381 tacaatatat tattagtata taatctatat aaacattact attgtttgat tatcttagct
     4441 acagtttcca catgtgtaga atgagggaac atatctacag gttgtgcctc aacacattta
     4501 aatccgtgaa catttagata atctaaatcc cttgctaaag tagaaggatt acaagaaaca
     4561 tagacaattc tttccggatt cattgaaaca atagtctcta ataccttttc gtcacatccc
     4621 tttctaggtg ggtctacaac gactacattg gcagtcttac cctctctata catcttaggt
     4681 acaatttcct ctgcctttcc aacataaaat tcagcattat gtatattgtt taatttagca
     4741 tttatcttag catcttttat ggcatcatct ataatttcta ttccataaac ctttttagcc
     4801 ttttgtgcca aaaataaaga tattgtacct atcccacagt aaatatcaaa aacagtatca
     4861 gtatcattta aatttgcata ttcaagagcc ttatcataca atactttagt ttggacaggg
     4921 tttacttgga aaaatgataa tggtgaaatc tcaaacacta agtctcctat ataatcgttt
     4981 atttttccat ctccatatat aactatattt tctcttccta gaatagcatt cgtatctttt
     5041 tgatttacat ttacaaccaa agtcttaaat ccaggtatat tttccttaag cactgaagct
     5101 aattctttaa gatatggaag tttgtttcca tttgctacta atacaaccat tacttcttta
     5161 gttgtaaaac ctatttttgt tactaaatgc ctaatcaacc ccgtgtgagt cttttcatca
     5221 tatatgctta ccttataggc ccttatatat gtttttatta ttttaacaat tttatcattt
     5281 atctcatgtt gtattacgca tttttctgtc gatattacat catgagtctt ctttttatag
     5341 aagccaataa ttggaatacc attattcttt tgtattggaa attgtgcttt atttctatat
     5401 ctatatggat tatccattcc tatagtgtca tgaacttcta catcctctaa cttacctatt
     5461 ctcgaaagta cttgtttaac ttcatttgtt ttcatttcaa gttgtttatt ataatctaag
     5521 tcttgtatct gacaccctcc acaatcccta agattgtcac tacacactct tttcaccctg
     5581 aatggagact tttctattat ctcaacaata tctcccacag cataattttt ctttacttta
     5641 ttaatcctaa ctttaacttt atcatgtatt aatccgccct ctacaaaaac tgtaatacca
     5701 ttgtactttc ctactcctac tccgccttga ccaatgtcta ctatatctac aatatacatc
     5761 tcgtttttcg aaagcataaa tcaccctcca atcaatctat tatatttaaa tctttacaaa
     5821 cttttttctt taaatttata ttaaaatatt gctattaatt aaactatatt ttttactaag
     5881 ctacaatatt ttattttacc aaaaaaaaag gagcttataa agccccttag taaataaatt
     5941 tattattttt cttataaaac tctagttgaa cctctatata ccacgcctct tgatgcatcc
     6001 acagttacaa cttctccatc ttttactaga tttgttatat cagctgcaga cacaataact
     6061 ggtatatcta aatttatacc tacaatagct gtatgtgatg tcattccacc attctcagtt
     6121 actacagctc ctgctttttc tatataattg ttcatttcag catcagtagc agtagaaaca
     6181 agtatgtcgc cttcattaaa gtctacacaa gcatttccat tctttattat acgaacttta
     6241 ccttctactg tttgagtacc tacacctata ccttgcacga tttcttcgct tattacatga
     6301 acctttatta aattagtagt tccacttact cctactggta ctccagcagt tataactact
     6361 aattccccat tatctatata atcagcttgt ctagctgcct caattgcctt ttctataact
     6421 tcatctgtat ttcctgcaac agaagactta actggatata ctccccatgt aagagctaat
     6481 ttattcatag tcttttcatt atttgtagta gctattattg gagattttgg tctgaattta
     6541 gataccattc tagcagtata tcctgaagaa gtagatgtta ttatagctga tgcatttaaa
     6601 tctactgctg ttgtacaagt tgcatggctt attgcatctg ttacagtaac attgttagta
     6661 ccattttcct ttagtaatct atcataatct aaagtctctt ctgttctttt tgctattgta
     6721 gccatcattt ttactgcctc tacaggatat tttccagcag cagtttctcc agataacatt
     6781 atcgcatctg ttccatcata tatagcattg gcaacgtctg taacttctgc tcttgttggt
     6841 cttggatttc ttatcataga atcaagcatt tgagtggcag taacaactgg ctttgctaat
     6901 tcattacatt tttttatcat cattttttga actattggca tctcttcagt tggtatctca
     6961 acacctaagt cacctctagc caccattata ccatcagaaa cttttaatat ttcatctagg
     7021 ttctctacac cttcttggtt ttctatttta gatattattt gtatatcagt tgcattattg
     7081 ttctctaata cttctcttat tgctagtaca tcagatgcct ttcttacaaa agaagcagct
     7141 atataatcta ttccttgact tattccaaac tctatatcac ttatatcttt aggagttatt
     7201 gctggtaaat ttatcttaac accaggtaca tttactcctt tatgattttt aactattcct
     7261 gaattttcaa caacacaaac tatatcttct ccatttattt cttttactct taagccaact
     7321 aaaccatcat ctattagtat agaatctcct gatttaacgt cttcagcaag acctttatag
     7381 cttactgtac acatttcttt agtccccata atatctttca tagttatagt gaacttttgc
     7441 ccttcttcta aaaatacctc tgggtcttca aagttacctg ttctaatttc tggaccttta
     7501 gtatctaata atatagcaac tggcttattt aatttttctc taactttctt tgccatatca
     7561 attctttctt tatgttcttc atgcgaaccg tgagaaaagt taaatctaca cacatttaga
     7621 ccattttgca taagttgagt taaaacttcc tcactttgtg atgctggacc tagtgtacaa
     7681 acaatttttg tcttctttac attatttaac atatttgctc ctcctgagat attattccac
     7741 agatttattt ttaatactaa aacttatata gataatattt ttgccatctc ataagcttct
     7801 ttatcaaata ctttcttttg agctaaagct tcacttattt ctaaatcaat tattttgttt
     7861 tcttttattc ctacaactct agctgatttt ccatctaata ataattctac tgctcttact
     7921 ccaagtctac ttgctagtat tctatcagat acagttgggc ttcctcctct ttggacatgc
     7981 cccaatacag tgactcttaa atctgctcct gactcttttt taagttcctt ttctaaatca
     8041 ctagcacttc cgactccttc tgctaaaacg attatactat gtctcttacc tcttttttga
     8101 gtagtcttta atcttagagc aacttcatct actgtaattt ctacttctgg tactattata
     8161 gtttccgctc ctcctgcaag acctgcatat aaggctaaat ctccacagtg tcttcccata
     8221 acttctacta tgttaactct ttcatgagat gatgatgtat ctcttatctt acctatagca
     8281 tctataatag tattcattgc agtatcaaat cctatagtat aatctgtata tgctaaatcg
     8341 ttatctatag ttcctggtat gcctatagct gggaatccta agtcactaag tttttgggct
     8401 cctgcaaatg aaccatctcc accaattaca actaagcaat caattttata ctttttaaga
     8461 atttttactg cttttaatct accttcttct gttttaaatt cttcacatct ggaagatttt
     8521 aatatagttc ctcccctgtg tataatatct ccaacagaag ataagttcat ttcagttaaa
     8581 tcttcttcta gtaatccctt atatcctcta ttgattccat atactttgca tccataatat
     8641 attgctgatc ttacaaccgc tctaatcgca gcattcattc ctggagcatc tcctccactt
     8701 gttagtaatc ctatagtttt cattttttac ctccttggat tttatgtcaa ttttttatta
     8761 taatcattgt tattgtattc taatggactt tttttgtccc tatatcactt tttaatccca
     8821 tcaagactaa aaaaattaaa tgtccttaaa tgtccatttt gtgatattat atcacaaaac
     8881 ggacaatatt tttcatatta ttataatata tttagatttt tatataaaaa atcaagcttt
     8941 tacttttatg ttatctttag gaagtaactc ttctaagtta tttataaatt catcacatat
     9001 acaagtcaat gccccggtca ttttatatgc tttacgttta ccatttatat tttcatccat
     9061 agggtataag tatatactgt cattacctgg atattgtttg gctatttcta caatattatt
     9121 agttgtatca gtatcagaca tactatctat tttcaaatac aattttttac cactttctgg
     9181 cttaatattt tctacatttc tagttcttcc tgaattgtag tttctatctg caaagtcagt
     9241 atcatcattt atatctttta tctctctagc tataagtttt gcattttcgc cttcttttat
     9301 acttaatgtt ccttttacat atattatatt atcttcattc aaaatgacat tatacttttg
     9361 taataattga ggaaaaacta ttatttctat agcaccatac aaatcttcta attcaataaa
     9421 tgccataatt tcatttcgtt ttgttgtttt aatagtttta gttacaatca ttccacccat
     9481 tataacatct gtttcattca tttgtaggta tgactcttct tcctctttta atgaatttaa
     9541 ttttccatta tccatagatg ttttttcttg tagttctttt tcaaattgtg ataaaggatg
     9601 tccacttaca tacattccca agacttcttt ttcaaggtta agtctctctc tttcttcgta
     9661 ctcttgcctt ttaggcaaac tgtatatttg ttgaaaatca ctatcttcct cactatctcc
     9721 aaaagcatca aataaagaaa tttgaccttg aacatttttc tttctatcca tagatacact
     9781 ttctaataaa ctttcataac cagccatcag actagctcta ttttcactta tattatcaaa
     9841 agctccacat tttattagac tttctattac tctcttattt gtatcttttt ggtctaatct
     9901 tttgactaaa tctactaaat ctacaaataa tccattagat tctctttcag cgattatatt
     9961 gtttattata tttacgccaa cattttttac ggctgctaga ccaaatctta tattgtcgcc
    10021 ttcaactgaa aactttgaaa aacttttgtt tatatctgga ggtaatacat ctatttctag
    10081 tgctttacat tctcttatat actcaactac cttatcagta tttcccatta cactggttat
    10141 caatgctgcc ataaattcaa ctggataata tgtttttaga taagctgtct catatgctaa
    10201 aaccccatat gcagctgcat gtgatttatt aaatgcatat ctagcgaagt ctatcatatc
    10261 atcaaatatt ttattagcta tttcctcttc tacaccattt ctgatacacc ctgcaatttc
    10321 tatattacca tcttcatcaa atttaccatg aataaaatat tgtctttctt cttccatcac
    10381 gtccatcttt ttcttactca tggctcttct aactaggtca cttcgtccgt aactataacc
    10441 acctaaatct ctaacgacct gcataacctg ctcttgatat accaaacaac catatgtaac
    10501 ttccattata ggctttaatt tttcatgtag atatgttaca tcttttgggt tgcttttatt
    10561 ttttatatat gcaggtatag aatccattgg acctggtcta aatagggata ttcccgctac
    10621 aatatcttca aaattgtctg gttttagctg tttcataaaa cttctcatgc cagcactctc
    10681 caattgaaac acccctagtg tatttcctga tgaaagcatt tcatatactt tcgggtcgtc
    10741 ataatccatc tttgaaaagt ctattttttc tgtgtaattt tttataactc tatttttttc
    10801 tattaaatca agagtatctc ttataactgt aagagttctt agcccaagaa aatccatctt
    10861 taaaagccca agttcttcaa gtgttgtcat agtaaactgt gttgtgattg catcttgatg
    10921 tttgtacaaa ggtacatatt catctacggg attttttgat ataacaactc ctgctgcatg
    10981 agtagaagca tgtcttagca ttccctctat ctgttttgat atatttatta tttcttttgt
    11041 ttccgggtct tggtcataca attctttaag attaggattt gtatctaggg ccttatctat
    11101 tgtcattcct aaagcaaatg gtatttcctt ggctaccttg tcaactttat tgtagcctat
    11161 atccaatacc cttccaacat ctcttattgc agcttttgca cccattgttc caaaagttat
    11221 tatctgggct acatggtcat caccatattt tctctttaca taatctataa cttcttctct
    11281 tctctcataa caaaaatcta tatctatatc tggcatggat atacgttctg gatttaaaaa
    11341 acgctcaaat aatagagagt actttattgg gtctatatca gttattttaa gtgtatatgc
    11401 tactatcgaa ccagccgcac tacctctacc tggtcctact ataatattat tttctttaga
    11461 aaaatttata aaatcccaaa caattaaaaa atactctaca taacccattt tttcaattac
    11521 atctaattca taatttaatc tctctagtat ctcattacta ggattatcat atctctcttt
    11581 taatccatta aaacacaact cccttaaata agtttctggt gtatatcctt ctggaacatc
    11641 atacttagga agatgtatag tattaaaatc aaactccaca ttacacatat cagctatttt
    11701 cacagtattg tcaatagcct ctaatgcata tggaaataat tcttccattt cttctcttga
    11761 ttttaaataa aactcatcac taccaaatct cattctattt gggtcattta atgtttttcc
    11821 catttgaata cacataagta catcatgtat tttcgaatct tctttattta catagtgaac
    11881 atcattagta gcaactagtg gtataccagt ctcttttgat aattttacta aaccagagtt
    11941 tacttctttt tgctcaggta aattgtgatc ttgaatctcc aaaaagaaat tttcttctcc
    12001 aaatatgtct ctgtagtcaa gagcaaattg ttttgctttt tcataatttc tattcattaa
    12061 agcacgtgct acatctcctg caaggcatgc agaaagtgct ataatccctt tgttatgttt
    12121 tttaagttct tccatgtcaa ctctaggctt atagtaaaaa ccttctacgt atgaagttga
    12181 aactattttt attaaatttt tatatccttc catattctta gctaacagaa ctaaatgtcc
    12241 ttgatatttg tcatagtttg ggtctttatc tctcaatcca cgtgcagctg tatagacttc
    12301 acaccctata attggcttta ttccttcttt tatagctgtt ttgtagaaat ctataacacc
    12361 aaacatacaa ccatggtcag ttatagctat tgagctcatg tttagttcct tagccctttt
    12421 tataagtttt ttcaccctcg aaaacccatc aagtaaacta tactcagtat gtacatgaag
    12481 atgagcaaaa tctttgttca ttaaatcacc tcctgcttta taattttaat tttaccacaa
    12541 atatatgtcc taaaacaaaa acagagactt ttatctcaaa ataggaatta acttcaacgt
    12601 ataccattat atgttataaa ttaatgctta ttctgagatt gtcccctcaa tttattgcta
    12661 tgattttttt ttcaaatctg ttgcaatttc ttctattttt ctaagtctat gattgactcc
    12721 agattttcct attggtggtt ctaacatctc tccaagttct ttgagagtca tatcctcata
    12781 ctcgattcta atcttagcta tctcttgtaa attttctggc aaactgctaa ttcctatagt
    12841 ctcttgtatg agcttaatat tttctacttg tcttactgct gcatttactg ttttagaaag
    12901 gttagctgtc tcacaattta ctatcctgtt tacattattt ctcatttctt ttactatttt
    12961 agtattttga agacttaaaa gagcgtggtg tcctcctata atactcaaca aatctgatat
    13021 ttgttcactc tctttgatat aaacaacgtg attatttttt ctagccacaa ttttactatt
    13081 aaaacctaaa gagtttataa gttcttttag agaatctgca aactcctcat tattagttac
    13141 aaattccata tgatagttct tttctgggtc gcttatagaa cctccaccaa gaaaagctcc
    13201 tcttatgaaa gctctcttac atccttcatg cttaattaag ttctctgaaa ttttgtttat
    13261 agtaaaaaat ccttctttat cttcaagtat acctaacttt tttaataaca tttctgaacc
    13321 catttcgctt gttaccatta atacataact gttatttctc tttagcattt gattcttatt
    13381 tactgagatt gtagtattga tattaaaatt cttttttaat aatttaaata ctttacgggc
    13441 tattgaattt aactctgttg ttatctttag atttagcttc ttatatccaa caatttgtat
    13501 acttccccct gatttaacta gagctgacaa ttcagctata ttacaacatt cattcccaga
    13561 tataactctt gctagttcat ttttggtttc agttgaaaaa gacatatcta tcacctatta
    13621 actaattttt ctttaacctt ttttttattt cttgtaaggc aacctttatt atctcctttt
    13681 catcatcata cctagctaag tctactactc tatctaggtg gataaattta gcatcaataa
    13741 agccttcctc tttttgtgga atagtatcca tattctttgc ttgcatcaaa taccaaaaaa
    13801 ctgttttatg aactgctcta ttttcatccc agttttcttt gaatgtatag tgtatttcac
    13861 ctaaatattt caatatatct gcttttactc cagtttcttc acttacttca cgtaatgctg
    13921 cctcttggtt attttcccct tcttctactt ttcccttggg taacacccaa tctccattga
    13981 acttccttag taaaagaatc gtattgccaa acaggactac accaccagca ctaacctctt
    14041 ctctcatcga tgttcactcc ttaaaactaa cataatgata aggatttcta cacaattttt
    14101 taaaatcctt ttttactaac ttttgttgta attatgattt agggctaact caataactat
    14161 gttagatata tactttgcat catgtcttat ataattattt tttatttcaa ttaaattctt
    14221 ctctacagtt tttataccca tctcttttaa tttatctttt tgctttttat ctaacaagac
    14281 ttgctctgct ccatcttgtt tatataagtc aagcatttct tctggcaata tctcattatt
    14341 tgcgattaca taatctatta aattctcatc agtgtgtttt actatagcat taacatgctc
    14401 taatacattg tacccttctg tctcacctgg ttgagtcatt atatttgcta tatatacttt
    14461 tggagctaca gacgatttaa tagcgtctac aatcccctct acaagtaaat ttggtattat
    14521 acttgtatat aaacttccag gacccataat tataatgtca gcatcataaa tagatgcaat
    14581 aacatccttt aatggtttta catcttttgg atttaaaaaa attttatcaa tagagctttt
    14641 ttgaattttt gactcttcag gtatactaga ttctccattt attatattgc cattttctaa
    14701 tttggcaact aaatttacat cttccaaagt tactggtaaa actcttcctg ttatagcaaa
    14761 aatttcactt aatttatata cagctttttc aaagtttcca tacaacccat tcatagcagc
    14821 caaaaacaaa tttccaaaac tctgaccttt taaaagccct tctgtaaacc tatattgcat
    14881 aacttcattc attgttggct ctatatttgc aagtgctaat aaacagtttc ttatgtctcc
    14941 tggtgggagc attcctaagt cttctctcaa tacacctgaa cctccaccat catcagcaac
    15001 agttacaatt gcagttatat tttgcgtagt gtgtttaaga cctcttaaaa ataccgattg
    15061 accagtacct ccacctatca caaccacatt tggttctcta ttttcaacaa tagacctttg
    15121 aaatagtttt actttttcat tttttgcttt tttatatata aataacgata caattaatgc
    15181 aatccaacct aaaattccta caataataag taatttagcc atgtttgcct ccattatcgc
    15241 aacatagagt ctctatgttt ctttacaact ctatatccct tattagataa atcctccgct
    15301 ataagatttg ttatagtaac tgacctatgt cttccacctg tgcatccaac accaattact
    15361 agatgttgtt ttccttcctc tatatattga ggtactaaaa aatgaatcat atctaaaagt
    15421 ttcacataaa attcttcact gattttagaa ttcataacat aatctctaac ttctttatca
    15481 tcaccagttt tagctcttaa ctcttcaaca taatagggat ttggaagaaa tcttacatca
    15541 aatactaaat ctgcatcagc aagtatacca tgtttaaatc caaaagatac tacagaaata
    15601 gttaggtttg gattatcttc accagaagaa tatattttct ttatttcttc cttaaggtct
    15661 ttaggtttca tgttagttgt atcaattata catgtagata actcctttaa aggttccatt
    15721 atctttcttt ccatttttat accttctgga atctgcatat cttttgccaa tggatgattt
    15781 cttcttgtca ttttatatct ctttagcaat acatcatcat tacaatccaa atataccatt
    15841 tcatattcat aattttcttt ttctaaataa tttaagcttt catgaagcgc ttcaaaaaac
    15901 tttctccctc ttatatctat ccctagagca actttatcaa tacttgaatt tggttgataa
    15961 cataattctg caaatttagt tatcaaagca ggaggtagat tatctacaca ataaaatccc
    16021 atatcctcta aagctctcat tgtctcactt tttccagatc ctgaaagacc tgtaactata
    16081 acaaatttca ttgctaactc ctccctttta tcttatgttt attatattat aatgttttct
    16141 actaacgata tatccagatt agagtcagat atagtcttca tagctagttc aaaatcacca
    16201 actctttctg gacaatgtgc atctgagcct attataaatt tattttctag cccttttatt
    16261 ttatttaatt gatttacatt caaaaaagaa tggctactat ttatctcaag tctagtattt
    16321 gtcttttttg ctgtctttgc tacttcttct atatacacat cgcctttatc tcctggatga
    16381 gtaattataa aaatatcatt attacttatc gcatttatta cagcttttgt attatattct
    16441 tttgcttttt cagttttaaa aatatagtta ttacaatgat ttaataagct tcttaatgat
    16501 gttggagtag aaccaaaatg atatccagcc ataatataat caaaatctct aataaattta
    16561 tcatccatat ctatatttcc tttatcatct aatatgttac actccatacc taaaagtata
    16621 tttatatcag tgtacttatc atttaaataa tctacttctt ctctcatttt gagaatatct
    16681 tttttcttta caccatatgc aatatgttta taactatggt cagatattcc tattgttttt
    16741 attcctttag aaatggctac ctttacatta tcctcaatag tccctttgcc atgactatat
    16801 aatgtatgtg tatgataatc agccagtatt ttcatttgtt aatcctctcc aagtattttg
    16861 acttcttctt ccaacataac cccaaacttg gcatatacag cactttttat aacatatatt
    16921 aaatccaaaa tatctttagc acttgcttct ccttgattga ctacaaatcc acaatgcttc
    16981 tcagatactt gtgctcctct taaagtaaga cctctcaatc cagtttcttc tattaattta
    17041 cctgcaaaat atcctgttgg tctcttaaat gtacttcctg cactagcaaa atttaatggc
    17101 tgtttagtta ttcttctcgt cgctaaatca tccattaaac tttttatttc atcataattt
    17161 ccttcttgta attctaattc tgctgataaa gctatatatc cgtttttcga tattatactt
    17221 tttctatacc caaattccat ctgttcattt gataattcaa atatattgcc ttccatatcc
    17281 atcagtctta ctgacttcac tatatccttc atttcaccac catatgctcc agcattcatg
    17341 gctaatgctc ctcccaatgt gccaggtatt cctgatgcaa actcaaaccc ttttaattct
    17401 tgcttttgga gagctttccc taaaactgat aataaagctc ctgactgagc agtcatccta
    17461 gtatcattta tctcataaga attgaaatta tcagctaatt ctattaccac tcctcttatt
    17521 ccaccatctt taattaaaat gtttgaacca tttccaatta ttaaatacgg aatagactct
    17581 ttttttacca acttaagtac attttttaat tgttcttcag ttctaggtct aactaatata
    17641 tctgctggtc ctcctaccct aaatgaaata tgttttttca taggttcatc gacttttata
    17701 tcctctttac ttaatatatt taataaattt atatatatat cttgattatt cattgtattt
    17761 cctcccaaat tatactgaac tttagctgtc attattattt aaattacatt aatatatagt
    17821 attaactata ttcaataata tatgattttg cttatcatat ggattttata ttttaagctt
    17881 cttaattaca aactatattc aataaatata taataaagta aaaaaaaaaa aataacaaca
    17941 tataaaagaa tataaataat ttaaaaaaag catcaatatc actgatatca atgctttaaa
    18001 aggcaattta attcgtatta tttatctaac tatttttgac atagcaaaga taataaatcc
    18061 ctccaactac tatggaacct ccaacgatat ttccaagtgt tacaaatacc aaattagtta
    18121 taaattgaac catagttata tttgctccta atgccattcc cattggtata aaaaacatgt
    18181 ttgcaacact atgttggaat ccacataata caaatagcat tattactgtc caacatgaag
    18241 ccaattttga cattatatct tgagatgctg tagccatcca tacagctaaa acgactagaa
    18301 tattacaaag tattgctttt aaaaacattg atgctatagt tgaattaacc ttagcttctg
    18361 ccacagctat agcttttgta gctgcatctc ctgtcaatgt agaagaataa aacacaagtg
    18421 caactagcaa aattgaacct actaaatttg caaaataaac cagtccccag tttcttaaca
    18481 tttttcctaa tgttattttt ttgtccataa gtgcaatagc cattaaagtg tttccagtga
    18541 ataattctgc tcctgccact actacaagca taagacctac tggaaagacc atagcactta
    18601 aaaagctagc tacccctggg tctatcttgc caaaagtttg actaactatc atactcccca
    18661 atgccccaaa acctataaat gctcctccaa ataaacctaa tagaattgca ttttgtgtcg
    18721 aaatatttgc ttttttaatg cctgcactta tagttgcttg tgcagtttcc ccaggtgtca
    18781 agaatccttt actcataaat ccttccccct taaaaattat actttccctt gtctttttat
    18841 ggcaataatt atataataac aatatgatat ataataaatt ttattaacat aaaaaatata
    18901 ctatatactt atatatactt gtctcatata attatactat ttattatata acaactttgt
    18961 taatttcgaa ataatttata ttgaatttga aaaatttacc ttttgattat ttattttact
    19021 ttttaattat tgaggtatta tatataatag atatatgttt gtgttattat atataattac
    19081 ttattttaat aaatatttga aggagggaat tttatgtttg atatatcatt tttcgaaatg
    19141 tcaatatatg aaatagcagt tactacaata tatataatta atttcatggt tatactaaac
    19201 cttatcttta gagaaaaaag aaacataaat acaactttaa catggcttct tatattagta
    19261 ttgattcctg ctcttggatt catactttat atagcttttg gcagaaatat ttcaaaaaac
    19321 aatatgttta gattgaaaga aaaggatgat aagataatca aaagtaatat actagatact
    19381 caggttaaac tccaatctac atctgaaatt gattcagata tacatcaaca taaggatatg
    19441 atttatgcat tggctaattc aaataatgct cattatacca ataataacga tgtgtggatt
    19501 tatgctgaat ctagtcaatt ttttaacagt cttcttgaag aacttaaaaa agctaaaaaa
    19561 tatataaaca tacaatttta cattttcaaa gatgacaaaa tcggaactga aataatagac
    19621 attcttatag acaaagctaa agaaggtgtt gaagtaagac ttttatttga tgcagttggt
    19681 ggtagaacac taaaaaatag tacactttcc agacttaaag aaagtggtgt taaagttgga
    19741 agcttcttcc catcattctt gaaaattgta aactttaact taaactatag aaatcaccga
    19801 aaaattgttg tcattgatgg taaggtagga tttgtaggtg gatataatgt tggtgatgaa
    19861 tatttaggta gaaatccaaa atttggtcta tggagagata cacatactaa gcttactggt
    19921 gattgcgtaa ttgacctaaa tatgagattc atccttgatt ggagatatac aactaaagaa
    19981 gacttagatt tagaaaaata ctttatagaa gaagatacaa attctaatca tccttctgaa
    20041 aatattggga ttcagatagt atcaagtggt ccagatatat cagaacttga tgagattaaa
    20101 tatggttacc ttaaaatgat tcagaaagct agaaagtata tatacataca gagtccttat
    20161 ttaatacttg actcaacttt tatagatact ttaaaaatag cctgtttatc tggtgttgat
    20221 gtgagagtga tgattccttc taaacctgac catccctttg tatactgggc atcatattca
    20281 tatgctggag aacttttaaa gtttggagct aaaatctata cttatggtca aaatgcattt
    20341 ttacatgcta agacaatagt tatagatgac tctatatgct ctataggaac agctaatatg
    20401 gatatcagaa gttttgagct taatttcgaa gttaatgcat ttatgtactc ttcaaaaaaa
    20461 gcattggaac aaagaattat atttgaaaat gatattttaa attctaagga aataacatta
    20521 gatatatata attctaggtc tacttatata aaaatcaagg aatcaatttc aagactatta
    20581 tcagcagttt tataaatctt ttattttata aaaattttac attttggttt attttttaaa
    20641 gttttttata tgtattattt tttttttatt gaatttagct catttttttt atttttttta
    20701 actattctga attattttat attataatag actagtatag tttttatttt taataggtaa
    20761 cttttttgca ttgtttttat aaataaagaa attgttgtat attattcttt ctttattgtt
    20821 ttggttttgt tcacccacat aatgttgggg tcaactcatg gttaattatt ttatgaaaaa
    20881 taataacttt aaaaagaaaa gggggatttg ttatgtgcga ttttatttca cacaacaagc
    20941 aattatttga cgaactagat atatttattg actctcttgc aacaaaggaa ggtgcgttaa
    21001 tacaagttct acatgaagcc caaggtatat ttggatatct tccaaaagaa gttcaacttc
    21061 atgttgctag aaaacttgga gtagctcctg caaaggtata tggggttgtt acattctatt
    21121 cttattttac tacagaacct gtaggtaagt ataaaatcag tgtctgtcta ggaactgtat
    21181 gttttgtaaa aggtgctgac aaaatcttaa gtgcttttga aaaacagctt ggcataaaag
    21241 ttggagaaac tactagtgat tttaaatttt ctttagaagg tttaagatgt ttgggggcat
    21301 gtggtttagc tccagttgtt actgtaaatg gtaaagttta tggtaaagtg aaacctgacc
    21361 aagtaagcga aatattagat acttatagag aattagaatt gaattgttaa gaggggtgaa
    21421 taaataatgc gtaaagtaaa ttcatttgat gaattaaaag ttttagctga tgagctgaaa
    21481 cctaatctta gcttaagaaa aaattattct aaggaaaatg tattaagaag agaattactt
    21541 gtttgttgtg atactggatg tacatcttca aacagtctag aaatagttag tgaattagaa
    21601 aatgaaataa agaaatcagg aatccaagat aaagttagtg ttcgtttgac aggttgtttt
    21661 ggtttctgtg ctcaaggtcc tattgtaaaa gtttatcctg ataacgtttt ctacgtaaaa
    21721 gttgagccat ctgatgctga aaagatagtt caaagccact taattagaaa tacagttgtc
    21781 gaggaattat tatatgagga agaatcttta agtaaaaaag ttgaagaaca agaagaaatg
    21841 tctttctaca aaaaacagtt acgtatagct ttaaaaaatt gtggtcttat agacccagat
    21901 agtatagaag aatatattgc caatgatggt tatttagctc taggcaaatg tttaacttct
    21961 cttactcctc aagaagttat tgcagaggta aaaacttctg gccttcgtgg tagaggtggt
    22021 gcaggtttcc ctactggctc taaatgggaa gctgcttcaa aaaatccagc tggtccaaca
    22081 gataaaaagt ttgttgtatg taatgctgat gaaggtgacc caggtgcatt tatggataga
    22141 tctgtacttg aaggtgaccc tcatagtgta ctagaagcta tggcaatatg tggatacgct
    22201 ataggttctg atacaggata catatacata agagcagaat atccaaaatc tatagaaaga
    22261 ttaaaagtag ccatagctca agctgaaaaa tacggtttac ttggcgaaaa tatcttaggc
    22321 actggattta actttaaatt agaattaaaa tatggtgcag gtgctttcgt ttgtggtgaa
    22381 ggtacagcgc taatgcattc aattgaaggt agacgtggtg aacctagaat gaaaacttat
    22441 agttcttcta agagtggtct atggaaatct cctacttgct taaataacgt tgagactttt
    22501 gctaacatac ctgcaattat acttaagggt ggagattggt ttgccaactt aggtactgaa
    22561 gattctagtg gtactaaagt ctttgctctt ggtggaaagg tagaaaatgt aggacttgtt
    22621 gaagttccaa tgggtactac tttaagagat attgtatttg aaattggtgg gggaatccct
    22681 gaaggtaaga aatttaaggc tgttcaaaca ggtggaccat ctggtggatg tataccaact
    22741 gaacatttag acactcctat agactttggt tcattaagtt ctatcggttc aatgatgggc
    22801 tctggtggta tgcttgttct tgatgaatct gactgtatgg tagatatagc caagttcttc
    22861 cttgagttta ctgttgaaga atcttgtggt aaatgtacac cttgtcgtat aggtactaca
    22921 agattattag aaatattaac taaaattaca gaaggtaatg gtactctaca agatttagat
    22981 gacctagaaa accttgctga aactatacaa actgcttcat tatgtggtct tggtaaagct
    23041 gctccaaacc ctgttttaag tactcttcaa tatttcaaag atgagtatat agctcatgtt
    23101 gtagataaga aatgtcctgc tggtaaatgt cagaacttac tttcttactt tataacagat
    23161 gactgtaagg gttgtacaaa atgttctaga gtgtgtcctg ctggttgtat aacaggttct
    23221 gttaaggaac aacatacaat agatacttct aagtgtctaa aatgtggtgc ttgtatagat
    23281 aattgtacat ttaacgctat aatcaagaaa taacttattt ggaggaggaa taacaatgag
    23341 tttagttaat ttaactatta atggcaaaca cgtttcagca cctagtggaa cttctatctt
    23401 agatgctgcg aaattaataa atataaaaat acacaacctt tgtcatttac atatgaatga
    23461 aatagataag cttgacactt gtgcttcttg tcgtgtttgt atggttgaga cagagagagg
    23521 attagttcca gcttgtggaa cagttataaa ggaaggtatg aaagttcaga ctaatagtgc
    23581 taaagcatta aatgctcgta gaactattgt tgaattattg ttatcagacc atccacaaga
    23641 ttgttttgtc tgtgaaaaaa atggagattg tgaattacag actatagctg ctgatttagg
    23701 agtaagaaaa ataagatatc aaggttctaa atcttttgca ggtaaagata cttctactaa
    23761 atctttagtt aaagaccatt ctaagtgtat attatgtaga agatgtgaga ctgtatgtaa
    23821 tgacatacaa acagtaggag cattatctgg agttaatcgt ggatttaata ctttagttag
    23881 tacattcttt aactctgata tggttgaaac agagtgtaca ttctgtggtc aatgtatatc
    23941 tgtctgtcca actggagcat taacagaagt agataatgta cctaaacttt gggatgtttt
    24001 aaataaaaaa gaaaagacta tagtagtgca agttgctcct gctgtaagag ttgctattgg
    24061 tgaagagttt ggattagaac cagggtcaat ctctacaggg aaaatggtag ctgctttaaa
    24121 agcacttgga tttgaacatg tatttgatac aaactttggt gcagatttta ctataatgga
    24181 agaagctact gaatttatag aaagaatcca aaaaggtgaa aatcttccta tattaacaag
    24241 ttgttgtcct gcatgggtaa acttcttaga gcacaattat ccagacaagt taaacttagc
    24301 atctagctgt aagtctcctc aaggtatgtt tggttctata gctaaaaact actatgcacc
    24361 taaaatatta ggaatcaatc ctgaagaact ttatgttgta tctgtaatgc cttgtgtagc
    24421 taaaaaatat gaagcttcaa gagaagaatt aagtgaatct ggaatactag atgttgacct
    24481 ttctataact actagagagt tagctaagat gataaaagaa gctgcaatcg atttacctaa
    24541 tcttcaagac caagattttg ataatcctct aggaaaatct acaggtgctg catctatatt
    24601 tggagcaagt ggtggagttt tagaagctgc cctacgtact tcatatgaga agataactaa
    24661 taagacttta gataatgtaa acttcactaa tgttagaggt cttaaaggaa ttagggaagc
    24721 aagtatagat gttgatggaa ctacagttaa tgtatgtatt gtaaatacac ttaaaaacgc
    24781 tagaaagatt atggataagg tcagaagtgg agaatgtaaa taccatatca tagaagttat
    24841 ggcatgtcct ggtggatgtg ttggaggtgc tggtcaacct tatcaccatg gtaatactga
    24901 aatagttgat agacgtgcaa atgcgttata tgaaatagat agaaataagg ctattcgtaa
    24961 atctcatgag aatcctgatt tacaagctat ttataaagac ttctttggag aaccaaatag
    25021 tgatgtagct cataaatacc ttcatactca ttactttgat aagagttgtg tctatggaga
    25081 gtgtccacaa gaatgtgctt gtgaagaagc taagtagtca taacaaagta taaaatttat
    25141 tcttaaaaaa ggattgtctt aaaatacttt tacgtaattt aagacaatcc ttattaattt
    25201 cacaaattaa attatatttc taaatagact tatttattaa ttaacctatc tattaattaa
    25261 agaatacctg ccattctcat aagttgtttt gcatttgtag ttttacatct tccatctttt
    25321 atcttatagt caaaatgaat tttatcgtct acatagtact ctgagaaatg atagtttaca
    25381 acttcaacat ctccgctacc tgaaaggtca catagctcaa agtcatgtgt tgtcaccata
    25441 cttataaccc agggttttga taatttcttt actgcctcac ttgctccaat aattctatca
    25501 gcagagttag ttcccttaaa aatttcatct actagaacca acattggcag ttcttttaaa
    25561 ctatattgaa tcattgattt tattctaaga atctcagcat agaaagttga tattccttga
    25621 cttacatcat cttgtattct catagaagta aatatagcca tacaggtcgc atcaaaactc
    25681 ttagcgcata ctggagcacc tgcatatgcc agcactaagt ttacaccgat acttcttaaa
    25741 aatgttgtct ttccagacat atttgaacct gtgataatac aagtctgaga atttaattgt
    25801 atcgaatttg ctatgacact tttttctgct attaatgggt ggtatacctc ttcaactttc
    25861 aatcttggag tatcttcata ttttattact ggaaaacatg tattttcctt tacatgagaa
    25921 acaactgtta aacttattag agcttcaaat tctccaatag attcaaacca atctctaatt
    25981 tgatttccat atataccttt ccatcgctcc aaagcttctg cacaatgata gttccacatc
    26041 aaaacaccac aggcaattat atatagtatc tgattatacc ttaggtttac agcatttcct
    26101 attgaattta attgtttaac acctcttgaa actccacttc ccttagaaag tttatcttgt
    26161 aattctttca aatatgcact ctcaaacgtc tctttttcta aaacctcaaa cattttttca
    26221 tatacttgta tacttctact aaatgaaaat aatggagcaa gagtttgcat aagtcttgga
    26281 tatccaaaac cactaaaccc taactggatt ataaaaagta aaaaaacagg taaaacaggt
    26341 aaaaatccta acatacaaaa tataaaagat aagattgttg cagttggtaa accccaagta
    26401 aaaatatgca tccattttgg tatatacaca ttcttatttt ctccatattc tataaacgat
    26461 tctatactac tatctgaatt gtttttttgc tctttaccaa ttatattact gagtgtttga
    26521 atatgaatag aaaaatcatc ttttgataaa agttctttta tagctctctg tctttctaaa
    26581 attatattct catctggatt ttcattccac aaatatttgg ctaaaaaatt tttcccataa
    26641 gatgtattag ctacacagat atattgatac aatgatgctc ttccaaataa gtctaaatct
    26701 tttgcttgcg aattttcatc ttttaagtat tctttaccat ctattttaaa ttccttccaa
    26761 ccatctccaa atctcttaat atacttattt aatacttcgc tcttactttt aaaatatgtt
    26821 tcttcttctt ttactttact atgaataact aagagtgcta taaatattat tattgataaa
    26881 actccaacaa aaatacctac tatattttta ttataaaatc caatagcaag ccctgctatc
    26941 actatcaaaa aagatattaa tcttgctgta cttatgttat ttgacttttt acttaagagc
    27001 aattcttttt cagtactact ttctaaaagt ttactaaaat attctattcc cataaaaaat
    27061 tccaactttc ttgttatata atgaaactca aatataaaat taatctagta ttattataat
    27121 ctaacactgt actttaaatt atccttatat aatatatctt attaataaac attatatata
    27181 caacttgatt ttaatttata aggtgtagga cataatccta atcaatattt aattaaatga
    27241 tgtgtagtcc actattattc agtactactt agtatcgatt aattttgata attttttagt
    27301 aaattcttga gctgcatcgt atcccattcc tctttgtcta aaattcattg ctgctacttc
    27361 taatatcata gcagtatttc ttccaggttt aacaggtaca actaatttct ctacattaac
    27421 accaagtatt tcttcatatt ctttatccag tcctagtcta tcataatact tagtttcatc
    27481 ccaagcttct aaatgaacta ctaaatctat cattttagaa tttttgattg cccctactcc
    27541 atataaactt ctaacatcta ttattcctat tcctcttatc tcaagaaaat gtcttattag
    27601 ttcaggtgac tgacccacaa gcatactttc atctaatttt cttatttcta cagcatcatc
    27661 tgcaactaat ctattacccc tttgaatcag ttctaatgct gtttccgact ttcctatact
    27721 actttcacct tttatcagta cacctatacc ataaatatct actagcacac cgtgaattgt
    27781 tgtatgtggt gctaacttat tatccaaata gtttgacagt ctatttataa gtctagtggt
    27841 atttctattt gtgctcaaaa gtattctttt atatttttta gccttttcaa ttacatctgg
    27901 cttgatttcc aagtctctag aaattattaa cgctggtatt tcatatgaga aaaatctatc
    27961 tagtacttct tcccgaatat gactatccat taatccaaaa aaattatatt ctgtctttcc
    28021 aactatttgt attctttcat atgcaaaata atcaaaatat cctgcaaact gtaatcctgg
    28081 tctatttata tcttgagagt agacataata atctacatca tcaggcatgt atactacttt
    28141 taacttcaac tcttttatta tctctcttat tgatacttta ttgctagttt ccattaattt
    28201 tcttcctttc taaaaaaatt ataaacatta tctgcaatgc ttttattcat tccatctact
    28261 tctaaaagtt cttccatagt agcttttttt atagcatcta catctttaaa gtgatttaat
    28321 aatgatttct ttcttttttc acctattcct tgtatatcat ctaagataga ttttgtcaaa
    28381 actttatttc ttagacttct atgatatgtt attgcataat tatgaacttc ttcttgtata
    28441 ctagcaataa atctatataa attagttgtt ttatctagtt ctatttcttt ttctttgcat
    28501 atcaatcctt tagttctatg cttatcatct ttgtacattc cccaaagagg tatatctaca
    28561 tcattgagtt ctagtacttt ttttactgca ctaacttgtc cttttccacc atccaacaat
    28621 atcaagtcag gtaaatttcc atgttttaat cttctatcta caatttcagc catagaatca
    28681 taatcattag gtccaataac tgtctttatt ttatatctcc tatattcctt cttatctttt
    28741 ttagcattcg tatacactac catagaacca atcgaatcta caccttgtat atttgatata
    28801 tcataagcct ctattcttat tggcaacttt tctagattta atatttgctt taattcttcc
    28861 aatgctccaa tacttttttc atattttctt ttattcatat cagaaaattt ttcaagatat
    28921 tctacagcat ttttcctaac catttcaact aagcttttct tctctccctt ttgaggaact
    28981 cttattgtta ctttttgccc ctttttagat gacagccatt cttctaatat agaactatct
    29041 tctatctcat cttctataat taattcttta ggtatatact cttgttcatt ataaaattgt
    29101 tttacaaatg aacttaatat agaagctctt ggactatcca ttaccccttc taatataaaa
    29161 tgttccctac ctacaatctt accatttctt ataaaaaata cctggacaca agcttcatta
    29221 tgagctcttg ccattgcaac cacatcttgg tttaagtcac ttacagtagc atctattttt
    29281 tgtttctgta tcatctcttc aaggctcttt atcttatccc tatatacagc agcctcttca
    29341 aatctaaagt tcatagaact ctcattcatt ttttccttta aaagttccat caatttttct
    29401 tctttaccag ataaacacat tataatctct tctatcattt ttccatactc ttctttagaa
    29461 acatttcctg tacaaggtcc taaacattta tttatgtgta gatttaaaca aggtcttgtc
    29521 ttattcttta ttgctttatc tatatctatt ttacagcttc ttattggata cgtactactt
    29581 ataagctcca aggtatcatt cacagcagtt atattggtat agggcccaaa atactttgcc
    29641 ttatctttaa gaactcttct aacttttaag attcttggat aatcttcatt cgtagttact
    29701 tttatatatg gataagtttt atcatctcta agcactacat tatactttgg tctgtatctt
    29761 tttattaaat tacattcaag tattaatgcc tctaactctg aatccgttat aatatactca
    29821 aacttatata tattcttaac catagatttt actttagatg tatggttttt tgaagattga
    29881 aaatactgcc ttaccctatt ttttagagat atggcttttc ccacatatat tatatggtcg
    29941 tatttgtctt tcattaaata tactccgggc tcagaaggta atttttttaa atgctcttgt
    30001 atatcaaaca tctcgccctc caaaacatta aattttatac taaaattata ccctaaaata
    30061 tgaattttaa aaagttatac aatttccagt gctttaaaca agttaaagcc catattccct
    30121 tctataattg atttgaaaac aatgttaacc atgaagagta atatggactt tactttgtat
    30181 tactatttac aacttatatt tgactaattt acttataaca aaacagttta tcgtatatct
    30241 gctctaaaat ttttcacaat ttatataact taagaaaaat atttctttaa gaattgacct
    30301 gtataagaac catcaacttt agatacttct tttggtgttc cagttgcaac tatagttcca
    30361 cccttatctc cgccttctgg tcctaagtct attacataat cacaagtctt tataacatct
    30421 aaattatgtt ctatgactat aattgtattt cctgtatctg ctagtctttg taatacttgg
    30481 attagcttgt ctacatctgc catatgaagt ccagtagtag gttcatctaa tatatacaaa
    30541 gtctttcctg ttggtctttt actaagttca gcagctaatt ttatacgttg tgcttctcct
    30601 cctgataatt gagttgaagg ctgtcctaat ttaatatatg aaagtcctac atccattaaa
    30661 gtttctaatt ttctttttat atttggtata ttttcgaaaa actcaacagc ttcttccaca
    30721 ttcatatcta atatatcaga tatagtttta tctttgtatt ttacttgcaa tgtttctcta
    30781 ttgtatcttt cacctttaca aatttcacaa ggaacatata catctggtaa gaaatgcatt
    30841 tctattttta ttattccatc acccttacaa gcttcacatc taccaccttt tacattaaaa
    30901 ctaaatctac cttttttata acctcttgct ttagcttcat tagtagatgc aaaaatatct
    30961 cttataaaat caaatacacc tgtataagta gcaggatttg aacgaggtgt tcttccaata
    31021 ggactttggt ctatatttat aactttatct atactttcaa ttccttttat ctccttatgc
    31081 ttaccagctc tttgcttaag tctattcact ttacttgcaa cacctttgta aagtatatcg
    31141 tttattaatg tactttttcc agaacctgaa acacctgtta tgcatgtaaa cttacctaat
    31201 gggaacttta catcaatatt tttcagatta ttttctgatg ctttaactat ttctataaaa
    31261 cttccatttc cttctctagt agtctcagga agcaatattt gttttttacc acttaaatat
    31321 tgacccgtta ttgagttctc attttcaatt atttcatcta aagtaccctg tgcaactatt
    31381 tcaccaccat gtatacctgc acctggacca atgtctataa cataatcagc ttctctcatt
    31441 gtgtcttcat catgctctac aacgattaag gtatttccta aatctgttag atgtctaaga
    31501 gtagttataa gcctatcatt atctctttgg tgaagcccta tacttggctc atcaagtaca
    31561 tataaaactc caaccaatgc agaacctatt tgagtagcta atcttatacg ttgcgcttct
    31621 cctcctgata aagttccagc ttttcttgat aaatttaaat aatcaagacc tacatctctt
    31681 aagaacatag ctcttccttt tatctctttt ataatctcat gagctataaa tctctgtttt
    31741 tctgtaagat ttatattttc cataaagtca atcaattcat ttacagataa gtttgtaact
    31801 tccattatat tttttccatc aactaaaaca gataaaactt cctttttaag tctcatccct
    31861 ttacactttg gacatggtct ctctgccatg tattcttcaa tcttatctct catgtaatct
    31921 gaattagttt ctctatatct tctctctaag tttactatta caccttcaaa gtatgattta
    31981 taatttctag ttcctccaaa ttttgactca taagtaaact ctacaattat attatcttta
    32041 ccataaagta attcctccac aaaatcatct ggtaaatctt taaacggtgt tgtcaaagat
    32101 acattaaaat gctctgctaa actttttatc attttactgt aataagtgtc atcattaaca
    32161 cctgttgaac cccatgctgc cactgcacct tgttttattg ataaatcttt gtttggtact
    32221 actaattctg ggtcaacttc tttactttcc ccaagaccat tacaaacatc acaagcacca
    32281 aagggagcat taaatgaaaa cattcttgga gataattctt ctatgccaat tccatgttct
    32341 gggcatgcaa atttagttga aaaaagaatt tcttctccat ctattatttg ggctattaca
    32401 agaccatcag atagcttaac tgcagtttca attgaatctg ctagtcttga ttctattcca
    32461 tctttaatta ctattctgtc cactacaact tctatattat gtttttgatt tttatttaag
    32521 attatatcat cactaacttc atagttttca ccattaactc taactcttac aaatccttct
    32581 tttttgatat tatcaaagac ttttttatgt gtaccttttt gtcctctaac aattggtgaa
    32641 agaatttgta atttcgttct atctggaaaa tctagcattt tatcaactat ttcttgaata
    32701 gtcatctgac ttattttttc accacatgta gggcaataca catctcctac tcttgcaaat
    32761 aatagtctca aataatcata tatttctgtt actgttccaa ccgtagaacg tgggtttttt
    32821 gaggtagtct tctggtcaat tgagatagct ggtgataaac cctctatata ttctacattt
    32881 ggcttttcca tctgacctaa aaattgtctt gcataagcag atagactttc tacatatctt
    32941 ctctgtcctt ctgcatatat tgtatcaaat gccaaagaag acttcccaga ccctgacaaa
    33001 cctgtaaaaa caataaattt atctcttggt aattctaaat ctatattttt taaattatgt
    33061 tcttttgctc ctcttattat aattttatct tccataatgt tgtttttacc tttctatttt
    33121 tccaattttt cttctaattg tttcacttta tctctaagtt ctgctgctct ttcaaattgt
    33181 aagttttgag cagcttccat catctctgat tttaatttat ctatattagc tcttatttcg
    33241 tctttatcat ctgtatcaga tattccatat acaacttctt cctctgcaac cttagtagct
    33301 tctatactat ctcttatatt tttctgtata gttttaggaa tgatattgtg ctcttcatta
    33361 tataaatttt gtatatctct tcttctcttt gtttcatcaa tagcattttg cattgagtca
    33421 gttatcctgt ctgcatacat aattactctt ccattttcat ttctagctgc acgtccaata
    33481 gtctgtatta aagctgtttc ggaacgtaag aaaccttctt tgtctgcatc taaaattgct
    33541 ataagtgaaa cttctggtat atccaatcct tctctaagta agtttattcc tacaaggaca
    33601 tcaaacttcc ctaatcttaa atctcttatt atttctgttc tttctaatgt aactatatct
    33661 gagtgtaaat atttaacttt tatccctatt tctttaagat agttagtcaa gtcctcactc
    33721 atttttttag ttaaagtggt tataagcact ctttcatttt tttctatagt tttagttatt
    33781 tctcctacca aatcatctat ttgattattt ataggtctta cttctacaat tgggtctaaa
    33841 aggccagttg gtcttattat ctgttctgct attgtctctg agtgttgaat ttcataaggc
    33901 cctggtgtag cacttacaaa caacatttga tttatatttc cttcaaattc ttgaaaattt
    33961 aatggtctat tgtcaagtgc agaaggtaat ctaaaaccat tctctataag tgatgttttt
    34021 ctagacctgt ctcctgcata catacctctt acttgtggta tagtgacatg tgcctcatct
    34081 acaattatca aataatcatc tgggaagaaa tccattaaag tatatggtct ttctccttct
    34141 gaccttcctg taatatgtct agaatagttc tctatcccct gacaaaatcc tatttccttt
    34201 aacatttcta tatcatactt agttctttgt tcaattcttt gtgcttctaa tagcctatca
    34261 ttttccttga aaaatttaat ttgttcttga agctcgtttt ctatttctac aattgccttt
    34321 tcaattcttt ctggcgttgt tacatagtga gatgctggga atataacaac atgatttcta
    34381 gtaccaacaa tcttccctgt tacataatca atttctgtta ttctatctac ctcatcacca
    34441 aaaaattcta ttcttattgc tttttcatca ttactagctg ggaatatttc tagtatatct
    34501 cctctaactc taaaggtacc tcgtgtaaag tttatgtcat ttctttcgta ttgtatctct
    34561 attaaccttt ttattacatc atctctgtct ctttgcatac ctggtcttat agataacata
    34621 agttctttat agtcttttgg gtcaccaagt ccatatatac aagatacaga tgatattatt
    34681 atagtatctc ttctctctaa aatagatgct gtagcagaat gtcgaagttt atctatttca
    34741 tcatttatgc ttgcatcttt ttctatataa gtgtcactgt gagctacata tgcttctggt
    34801 tgataataat catagtaact tacaaagtat tcaactgcat tgtctgggaa aaattcttta
    34861 aactcactgt aaagttgtgc tgctagagtt ttattatgag ccattattag ggtaggtttc
    34921 ttaacttgtt gaatgatatt tgccattgtg aatgtttttc ctgaacccgt tacacctaat
    34981 aatgtcgaaa atttctcatt tctatttata gaatccacta ttgatttaat agcttctggt
    35041 tggtcacctg taggtttgaa gtctgatttt attttaaaat ccatagtatc actccttttt
    35101 tcgaacatta gttcctgaca tgtattatta tatcatacct ttataaaatt gtttaagtta
    35161 ttttaaatat tttacccatt taaattttac ttaaatctaa aacataaaaa aagacttcta
    35221 tctttgcaat agaagtctat aattcatgga aaataaatac tttattcaac ttacataata
    35281 aaatcaaatg cttctttttc aactccatct aattttaaat taaacatttt taatatagtt
    35341 gctgcatgtg ctctcaggtc tccttcttct ataaccacac cacctttaat atttggtcca
    35401 aaagctataa atggaggtct attaccttta gtaggtaaat gaccatgtgt cgcaacagca
    35461 aacttgtaat cttttatatc tgaatctttt ataatacttc cttcgaaatc atttccaaat
    35521 gaaattcctt caagaccttc aattaccatt tcaaaatcac cttcaagacc aaggttagat
    35581 gcttcctctt tggtaaaaat attctctatg aataattctt ctttaaattc ttcaagcagt
    35641 tctcttaact ctgttaacct atctaagtta tttactatta tttgagctga tattccagaa
    35701 gaatttacat aggcatcaaa atccttaact tctccatttt caacttttat aaatccattt
    35761 gatttaagca agacatttgg atttataact ttatcaactc taagatgacc atggtcccca
    35821 agtattataa aatttgtatc tttgtatgta cctgcatcct ttgtagcctg aataatatct
    35881 cctagccatt tatcattcat ttttaatgct ttatctactt cgtcattaaa taagccataa
    35941 ttgtgtcgtg tatggtccaa tgtagctaaa tgtattagca ttaaatctgg tttatattcc
    36001 tttattatat ctactgaaca gtttactcca aataaatcca tgttgggttc taatttccaa
    36061 tcgatataat gacaatgtct attgtaaata ccgtccatta taaccttact ggaacttcgt
    36121 tcaaaagttt ctcttgggtc atcttctcta ctaggagccc atatttctgc aatattataa
    36181 tctatatttg gatttgctcc cattacaggc cataatacac tagaggtagt tagattattt
    36241 tcttttgcta catctataat agtttttgct tttatgtcct ttgagtacca gtaccagtct
    36301 ttattttctt tatttgggtc aaatttttca ttatgatata taccatgttt tttaggatat
    36361 actcctgtaa ccatactagt atgacacgga tatgtcagag tgggataaac acaatttata
    36421 ttttttacta tggagcaatt ttctagtata gatttaaagt ttggtagatt ttttacaaat
    36481 tccaagtctt tttcaaataa agaatctact gataatacta taacctttgt catttacatt
    36541 acctcttcat ttatatatta ttgaatactt ttaatcaact tacaagtcta tataattatt
    36601 tatttgtttt atctattact gcttgcattg cagaagttcc tttgcttact acatcttttg
    36661 gatttgcatt taaatcagta agcccctttt taatctcatc cattagctta tcagttgctt
    36721 ccttgtatcc atttaacatt ggaagtgcaa cagcatattg taattggtca gttgcaacct
    36781 tatattgagg tttttcttta tataatgttt gtaacttttc tgagtttgtt gcatcttcag
    36841 ttgttggtaa gtatcctgtt gatgaactaa actgaacgat tttatctgtt tgtgtcatcc
    36901 attctataaa ttctgcactt gcttcttttt ctttatctgt tccaccttca agcataacta
    36961 gattagctcc acctgtagga gttgcgtatt tttgattttt tggtaagaat gctgttgata
    37021 tttcaaactt accttctgtt tgttgcataa gtcctgctaa atctgctgtt gatgtaaata
    37081 tcatacctac tttaccattt acaaaatctt gttttgctac gtcccaggca ttataatctt
    37141 ctccaggagg cattttcatt attccagctt tcatcatatc ttgccagaac ttaactggtg
    37201 cttgtcctgc ctcattatta aatgctactt ttttaccatt agttatttct cctccacttt
    37261 gcattaccat agcttcatag aaccaaatat ctattggtgt ttcaaaacca taagtatctt
    37321 ctgatttatt tgtcatttta ctagcataat ccttaagctc ttcccatgat tttggacctg
    37381 aagggtcaag acctgcttta gttgccatat ctttatttat gtataatatt ggtgtacttc
    37441 tattaaatgg cataccaaca aacttatcct cataatatga atttgttaaa agaccagaaa
    37501 agaatctttc ttgatatgtt ttatcaaaat atttactcat atctactaaa gcacctgctg
    37561 atgcgaatgt acctgtttga gttatttcta ataatgttac atctggttgg tctttagatg
    37621 ttaaggctgc ctgtagtttt gttgcatttt catagtaatc tttctgtttt aacatattta
    37681 cttgtacatc cttatgttca ctattaaatt ggtcaaccat tttttgagca gtttctccat
    37741 tagttccacc taaaggagcc cagaaatcta tcttcgtaat attgctatca gtcttttctc
    37801 ctttagatgc atttgcatca ttagaatttg aacacccaac taaagaacat aataataatg
    37861 ttattgctaa tcctgttgct aattttcttt taagcttcat tttcatcctc caaatttagt
    37921 ctttaatttt ttattttatt cctgaataca taaaagcttc ttttactttt ttattcgcaa
    37981 atatataaac aagaattatt ggtaaaatta gaattatatt tcctgccatt attacattcc
    38041 atgcagtaat tccttctgaa gatttaagga gcgcaactcc tattggtaaa gttcttattg
    38101 catctgtatt tgtcattact aagggccaga aataattatt ccaatggtat ataaaattaa
    38161 ataatataaa tgttattact gctggttttg ccataggaac cattattcta aacattattt
    38221 ttaagtcaga agcattatct agtttagctg cttcaataat ttcatctgaa atctgcataa
    38281 aattctgtct aagcagaaat atcccaaatg aagatgtcat aaatggaatt ataagtggaa
    38341 cataagtatt tataaatcca aacttactca tcatcatata gactggtaga aaagttactt
    38401 gtggtggaat cataagtcct acaagcaaaa gcccaaatag cattttttca cctttaaatt
    38461 taatcttaga aaatgcatat gctgctggaa ccataactaa aaattgtaca attaaaacac
    38521 ttcctgttac aaatacactg tttagcaaat atctaaaaaa tggacctgaa tgccatgctg
    38581 tactataatt ttctaacact atatcatttg gtataatagt gggcggtaat tgcatcattt
    38641 cttgtggatt tttaaaggat gtagatagca tccatataaa agggaatata aatattgcag
    38701 ataaaagtaa tagaattaat atttctattg attttgatgc tatttttttt atatcaactt
    38761 tgtctttttt gataggttgt ataatatcca ttgtctcctc cttttggata aaccttataa
    38821 tatctacttt ttctttattg ataatgaact ttctttgata agagtctaaa gttagcatat
    38881 gtagcaatca taactatagc taacaaaaac atactcgctg cactcgcttg ccctatgtca
    38941 tagtatataa atccagactc atatatataa taagataaca tgttagttga acccactggc
    39001 ccaccttgtg tcattatact tatctcatca aatacttgaa aagatgcagt tgttgttgtt
    39061 atcataagaa aaaatattgt tggtgataat agtggcaatg tcactttaaa gaaattcgtt
    39121 attttgtttg cattatctaa tttagatgct tcatatatat agtttggtat ggatttaaga
    39181 cctgataaca ctattaagat attatatcca agagtcttcc atattcctat tagaattagt
    39241 gacattaaag ctgaactttc acttgaaagc cactttgatg ttggtaaatg taatgtcgat
    39301 agtatccagt ttaaaaagcc atattgtggc tccataatcc aaagccacaa tacagctaca
    39361 gatactagtg aaattacatg tggtgtaaag attatacttt gcgttaaatt gtgtattata
    39421 gaatttttat ttagccaaac agcaagtact atggctagtg atatagatat agtcaccata
    39481 aaaaaagtat aaattgcagt gtttgttata gtttgtataa actctggatt ctttaaaagt
    39541 tctgtataat tgtttaagcc tacattttca aaggttgaac taagaagact accagatttg
    39601 aagcttagag atatcgtctt aattattgga tagactataa acaataaagt tcctataata
    39661 gcaggtgtta tatataaata tgctttatta aattgctttt tcataaatat ctcctttgat
    39721 tttagaatac atacttttac atacttttac atcttctatt ctttctccat ttttatcaaa
    39781 ataatataaa tctttttcta atacacttat tcttaaagtt cttccaatat caaatatatc
    39841 attttccgtt ttgactctta tctctctatt aagaacagat aaacaatata tagtttcatt
    39901 tcccaacact tctttagtta caacttttcc aaatagacta aatacatcat catttttccc
    39961 atctatgttt atactctcta gtgttgcttt ttctggtctg aatccaaatt taatatcatt
    40021 ttttatatct agtatgttca tacaaggact ccctataaat tgagctacaa ataaattttt
    40081 aggattttga tatatcttct ttggagaacc tatttgcatt atctttcctt tgttcattat
    40141 aactatctta tctgccattg acattgcctc aacctggtca tgagttacat aaacaaatgt
    40201 agactttagt ttttgatgta attgtattaa ttctgttctc atttgatttc ttaatttagc
    40261 atctaaattt gacaatggtt catccattaa aaataccttt ggatttttaa ccatagctct
    40321 agcaagtgcc actctttgtc tttgacctcc agataagttg cctggtttca catttaaata
    40381 ttctctcaat cctactacat caataacttc tgttataagt ttttctcttt tttctttttc
    40441 tacttttttg tttttaagac caaattctat gttttctcta acagtcatat gtggatataa
    40501 tgcataattt tgaaatacca tagctatatc ccttttacta gcatccgttt ttgtaacatc
    40561 attttcttca atcttcaacc tacctgaagt tatatcttca agacctgcaa tcattcttaa
    40621 cgtagtagat ttaccacatc cacttgggcc taccaatact gtaaaagaac catcttctat
    40681 agtaagattt aaattttcta taactgtatt ttttttatta taagattttg ttacattttc
    40741 tagtcttata tctgccattt ttatcctccc aaaatattta atttaattct acgatttact
    40801 tatagattaa taatactctt aatttgtaaa ggatatatta agacaaagtg aatatatggt
    40861 aaacttatta aaataaaggt taaattataa acattttttg ttaaatatac tgaagttaag
    40921 atgatataca gcttatgtta gctataattt tctatatttt tcatattcat ggtttgctat
    40981 cacaatgtaa ttttaattta tgaagagtca tataaaacta tttatttttt atataatttg
    41041 gtttgaaagt aaaaaagacc tctatggggg atagaggtct ttaagtgggg gagattgagt
    41101 aatttatttt tgctatatta agttttacaa ttatattatg tcccaaattt acaaggttta
    41161 aacataaaaa ataaaaattt tttaattttt ataaatttac c
//
LOCUS       DAEHWO010000032        39613 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEHWO010000032 DAEHWO010000000
VERSION     DAEHWO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39613
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.032"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            39..155
                     /gene="rrf"
                     /locus_tag="KNP54_001975"
     rRNA            39..155
                     /gene="rrf"
                     /locus_tag="KNP54_001975"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            275..466
                     /locus_tag="KNP54_001976"
     CDS             275..466
                     /locus_tag="KNP54_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBF0892877.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            621..2030
                     /locus_tag="KNP54_001977"
     CDS             621..2030
                     /locus_tag="KNP54_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBF0892878.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVEDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQIIDLEDI"
     gene            2161..2850
                     /locus_tag="KNP54_001978"
     CDS             2161..2850
                     /locus_tag="KNP54_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBF0892879.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2853..3788
                     /locus_tag="KNP54_001979"
     CDS             2853..3788
                     /locus_tag="KNP54_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBF0892880.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3785..4678
                     /locus_tag="KNP54_001980"
     CDS             3785..4678
                     /locus_tag="KNP54_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBF0892881.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4756..5502
                     /locus_tag="KNP54_001981"
     CDS             4756..5502
                     /locus_tag="KNP54_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBF0892882.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5503..6336
                     /gene="rsmI"
                     /locus_tag="KNP54_001982"
     CDS             5503..6336
                     /gene="rsmI"
                     /locus_tag="KNP54_001982"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBF0892883.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEIRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6359..7063
                     /locus_tag="KNP54_001983"
     CDS             6359..7063
                     /locus_tag="KNP54_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBF0892884.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7251..7679)
                     /locus_tag="KNP54_001984"
     CDS             complement(7251..7679)
                     /locus_tag="KNP54_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBF0892885.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7716..9146)
                     /locus_tag="KNP54_001985"
     CDS             complement(7716..9146)
                     /locus_tag="KNP54_001985"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBF0892886.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9278..9862
                     /locus_tag="KNP54_001986"
     CDS             9278..9862
                     /locus_tag="KNP54_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBF0892887.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9878..10399
                     /locus_tag="KNP54_001987"
     CDS             9878..10399
                     /locus_tag="KNP54_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HBF0892888.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10465..10711
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10795..12732
                     /gene="metG"
                     /locus_tag="KNP54_001988"
     CDS             10795..12732
                     /gene="metG"
                     /locus_tag="KNP54_001988"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBF0892889.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12762..13532
                     /locus_tag="KNP54_001989"
     CDS             12762..13532
                     /locus_tag="KNP54_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBF0892890.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13870..14301
                     /gene="phnG"
                     /locus_tag="KNP54_001990"
     CDS             13870..14301
                     /gene="phnG"
                     /locus_tag="KNP54_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBF0892891.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14316..14891
                     /gene="phnH"
                     /locus_tag="KNP54_001991"
     CDS             14316..14891
                     /gene="phnH"
                     /locus_tag="KNP54_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBF0892892.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTNLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14894..16009
                     /locus_tag="KNP54_001992"
     CDS             14894..16009
                     /locus_tag="KNP54_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBF0892893.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRAAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKIKHPIYEDEEITIGDMLVTECEIVSKASQNK
                     TENSKNNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIKKFEEVSLGDI"
     gene            15999..16868
                     /locus_tag="KNP54_001993"
     CDS             15999..16868
                     /locus_tag="KNP54_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBF0892894.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16861..17727
                     /locus_tag="KNP54_001994"
     CDS             16861..17727
                     /locus_tag="KNP54_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892895.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQREFKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17768..18481
                     /locus_tag="KNP54_001995"
     CDS             17768..18481
                     /locus_tag="KNP54_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0892896.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18482..19651
                     /locus_tag="KNP54_001996"
     CDS             18482..19651
                     /locus_tag="KNP54_001996"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBF0892897.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19655..20491
                     /locus_tag="KNP54_001997"
     CDS             19655..20491
                     /locus_tag="KNP54_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBF0892898.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20492..21487
                     /locus_tag="KNP54_001998"
     CDS             20492..21487
                     /locus_tag="KNP54_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0892899.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21505..23193
                     /locus_tag="KNP54_001999"
     CDS             21505..23193
                     /locus_tag="KNP54_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBF0892900.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     EFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23205..24272
                     /locus_tag="KNP54_002000"
     CDS             23205..24272
                     /locus_tag="KNP54_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0892901.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            25036..26103
                     /locus_tag="KNP54_002001"
     CDS             25036..26103
                     /locus_tag="KNP54_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0892902.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNSAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26295..26825
                     /gene="rnmV"
                     /locus_tag="KNP54_002002"
     CDS             26295..26825
                     /gene="rnmV"
                     /locus_tag="KNP54_002002"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBF0892903.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26996..27865
                     /gene="rsmA"
                     /locus_tag="KNP54_002003"
     CDS             26996..27865
                     /gene="rsmA"
                     /locus_tag="KNP54_002003"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBF0892904.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27931..29193
                     /locus_tag="KNP54_002004"
     CDS             27931..29193
                     /locus_tag="KNP54_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892905.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEENEESDRDEDSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSDDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29344..30459
                     /locus_tag="KNP54_002005"
     CDS             29344..30459
                     /locus_tag="KNP54_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBF0892906.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30645..31541
                     /locus_tag="KNP54_002006"
     CDS             30645..31541
                     /locus_tag="KNP54_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBF0892907.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31611..32408
                     /locus_tag="KNP54_002007"
     CDS             31611..32408
                     /locus_tag="KNP54_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892908.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32463..33815)
                     /locus_tag="KNP54_002008"
     CDS             complement(32463..33815)
                     /locus_tag="KNP54_002008"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBF0892909.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            34034..34912
                     /gene="purR"
                     /locus_tag="KNP54_002009"
     CDS             34034..34912
                     /gene="purR"
                     /locus_tag="KNP54_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBF0892910.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            35068..35346
                     /gene="spoVG"
                     /locus_tag="KNP54_002010"
     CDS             35068..35346
                     /gene="spoVG"
                     /locus_tag="KNP54_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBF0892911.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35559..36938
                     /gene="glmU"
                     /locus_tag="KNP54_002011"
     CDS             35559..36938
                     /gene="glmU"
                     /locus_tag="KNP54_002011"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBF0892912.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            37033..37983
                     /locus_tag="KNP54_002012"
     CDS             37033..37983
                     /locus_tag="KNP54_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBF0892913.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38821..38906
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            39068..39589
                     /locus_tag="KNP54_002013"
     CDS             39068..39589
                     /locus_tag="KNP54_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBF0892914.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNTEGVTLTEAQSAKLLSDIGENKIYTSATTNSLGNPLTSNTKIDNNVLY
                     IVLIDNTVMDTTK"
BASE COUNT        15871 a         4319 c         7133 g        12290 t
ORIGIN      
        1 tattaaaaac ttaatagaaa tattaagcat aaagattatg tggttacaat agcagagagg
       61 atacacctgt tcccattccg aacacagaag ttaagctctc tagcgctgat ggtacttggt
      121 gggaaactgc ctgggagagt aggacgtagc cacgtaattt tttttatttt ttgtcaaaaa
      181 aaacaaaaaa tacgtatttc ttttttcatt tcgggaaaac taaacacagg aattatggac
      241 tttataaaaa tttaattctt gaggagtgat ataagtgaaa aaagttgctt taattttagc
      301 tataataggt gcgcttaact ggggtgcaat tggtattcta ggtacagact taataggtag
      361 tatctttggt ggaacatatg aaatggtaag tagaataata tacttcattg taggtttagc
      421 tggattatac ttaataccaa gtttaatgtc tgatgataga gaataattta tgcttttatg
      481 ttaaatacct cattctaaat gtttagaatg aggtatttaa ttttataaaa atattaattt
      541 gtttcttttt taatggtaaa atagataaga attgaagttt taaaaagaag tattatgtaa
      601 aaaaggagta ctattaatat atgtttatta ttaatgaatt aaataagatt gtaaatgaag
      661 aagtaatatc ttttcatatg cctggtcata aaaagggaca ggtttataaa aagttaggat
      721 ataaagatat actaaaaaat ttgtataaaa tggatacaac tgagatatta ggaacagata
      781 atttacactt tccggaagga attataaaaa attcacaaaa aaaagcatca agagtattta
      841 aaagtgatta tacttgctat ttagtaaatg gtagtagctg tggaatacaa tctgcaataa
      901 tgtcagtatg tagtcctaaa agtaaaataa taacaaatag agactgtcat cagtctgtta
      961 taaatggatg tattttagga gatatagata tagagtatgt gccttgtgag ataagtgaag
     1021 agacaaatgt cttaaaaggg atatctataa gtaatgtgat tgatataata gataaaaact
     1081 tggatgcaaa agcagtactg cttacttatc ctacatatta tggaatgaca tatgatttag
     1141 aatacatatg taattatgca catagcaaaa agatggtagt gatagtagat gaagcacatg
     1201 gtgcgcattt agggcttagc gagaggcttc ctaaaacagc tcttgagcaa ggcgcagata
     1261 tagttgtaca gagtacacat aaaactcttc cagcatttac acaatcgtca atgatacata
     1321 tacagggaga ccgagttgat atagataaaa tattgaacat gttaagaatt acagaatctt
     1381 caagcccttc atatttatta ttatcttctc tggaattagc agtagatata tatgaaaata
     1441 aaggaaaaga attaatggaa gagcttttaa ataatattat aactttcaaa aataaagttg
     1501 attcaaatat taatatatac gacacaaatg ataaaacaaa aatatttata tcatctaaaa
     1561 atatgggttt aacaggttat gaactagaaa atattttaag aaacaaatat aacatacaag
     1621 tggagttatc taattattat ggagttcttt taatatgtac aataggaaat actgttgagg
     1681 atttctctag tttagaaaca gcattaaaca atattgtaaa ggaagacttt aaatttgaaa
     1741 agttagaaaa taaaaaatac cctgttgtta ttccaaagaa aatattaaca cctagagaag
     1801 cattttataa aactaaaaaa agtgttaaaa tatatgacag cataggtaaa gtttgtggtg
     1861 aatgtatagt tccataccca cctggaataa gtgtaatatc tcctggtgaa gtaataagta
     1921 aagaaataat agactatcta atgttttgtc attctaaagg catgattgtg agtggattga
     1981 aagatgtaga tttaaatttt atacaaataa tagatttaga agacatttaa aaattatgat
     2041 ataaaagtag atagaagtag atagtttaaa attgtgaaga gaaataaata gactgcttat
     2101 atagagctat ctaataaaag tactaaaaaa gtaaaaagtg tttgtatgga ggatatgaaa
     2161 atgaaaggta agttaataat tatagagagt ggttcagatg caagtggaaa ggctactcag
     2221 acagaaatat tatatgaaag attaaaaaaa gaaggctata tgattaaaaa ggtagaatat
     2281 ccaaattatg aatctccatc atctgccttg gtgaaaatgt acctaaaagg agactttggt
     2341 aaaaatgcat cagatgtaga cccatatata gcatcaactt tttttacagc tgataggtat
     2401 gcatcattta aaaccgattg ggaggagttt tacaatgaag gtggaataat tatcgcagat
     2461 agatatacaa cctctaatat ggtacatcag gcctctaaaa tggatatttg tgatagagaa
     2521 gagtatttaa attggttagc tgattatgaa tttaatttat ttaagatacc acaacctgat
     2581 tgtgttatat ttttagatgt gcctattgaa tttagtaaaa agcttatgga gaatagaaaa
     2641 aataaaatta caggggaaga aaaaaaggat attcatgaaa gtgacataga gtatttagag
     2701 aaatcttaca acaatgcttt atatatagca gataaatatg attggaaaaa aataaattgt
     2761 gttttagata acaaattaag aagtattgaa agtatacata atgaaattta taaaatagtt
     2821 cttgattcaa taaaacctat ggagagataa atatgtattt tgaaaatatt atagggcaag
     2881 attttgcaaa gaaatattta acaaattcta taaagaaaaa taaacttaat aatgcgtata
     2941 tgtttgaagg aatggatgga ataggaaaaa agaaatttgc agatgaatta tcaaaactat
     3001 tacttgatta tgaaaatctc gaaaatagtc cagactatgt actcataaaa ccagatggaa
     3061 atagtataaa aatagctcaa atcagaaatt tacaatcaga tatagtaata agacctcata
     3121 aagactataa aatatatata atcaataatg ctgaaaaaat gactgtggaa gctcaaaatg
     3181 cacttttaaa gacgctagag gaacctccaa actatgctat aataatctta gtcacaaaca
     3241 acaaggaatc tttattagaa actataaaat ctagatgtga tataataaag ttctcaccta
     3301 taccaattga agacttaaaa cgttatttga taaatacagg tatagaagaa gaaagagctc
     3361 aattattggc tattttttcg agaggaagta ttgagaatgc tctaaatcta tctcagtctt
     3421 ctgagttttc aatgatgaga gaagatatac aacagtatat tcagataatg ttagataaaa
     3481 acatagtgga gattttaaat ataccaaata atatggaaaa atatagaggt aagattatag
     3541 ctttattaga tatgatgata aactattttc gagatatcat cctattaaaa gaaaatgtaa
     3601 acaagaacat gttaataaat gtagataagc tagttttcat tcaaaatatg agtggaaaaa
     3661 ttagttattc tcaattgtcc aagattattg atataataga agatgcaaag agtaaaataa
     3721 aaagcaattg caatttcaat ataagcatac aagttatgtc tttaaatata tacgaggtga
     3781 ttaaatgata aagatagtag gtataaggtt taaaagtgct gggaaaatat attattttga
     3841 ccctgttgat tttaatatag agcaagatat ggatgtagtt gtagaaactg caagaggctt
     3901 ggagtatggg aaagtagtcg ttggtccaaa agatatggat gaaagcgaat tagtttctcc
     3961 tttgaagcca attataagaa tagctacaga agaagataaa aaagtatatc tagaaaataa
     4021 ggaaaaggca aaagaaactt ttgagttgtg ccaacaaaaa ataaaagaac atgagttaac
     4081 aatgttttta atagattgtg agtatacatt tgataggaat aagttgattt tttactttac
     4141 agcagaagga agaatagatt ttagagaatt ggtaaaagac ttagctgcta tatttaaaac
     4201 tagaatagaa cttagacaaa taggtgtcag agatgaagct aaatctatag gaggtctagg
     4261 gccttgtggt agaaaacttt gttgttcatc ttggttaggt gattttcaac cagtttcaat
     4321 aaaaatggca aaagaccaaa gtctatctct aaatccaaca aaaatatctg gaatatgtgg
     4381 gagattattc tgttgcttaa aatatgagca tgatgtatat agtgaagcaa tagaaaaaat
     4441 gcctgttgta ggtgcattgg tgcaatcaga tgatggaaaa ggaaaagttg tagaagtgaa
     4501 tcctttatta gaacaaatta aagtggaatt tcaagacaag acagtaaaga tatacacaag
     4561 agaagatata aaaatactta gagagcctaa aaaatgtgat ggctgtggtg gtaaatgtaa
     4621 ggataatgat ggattagatg aagccacact aagagagcta aagaaattag aagattaaat
     4681 ttaaggtagg gcttttccta ccttttttaa agcaattaat gcttaaagtt attaatattt
     4741 gaggagaatt tatatatgca attaaaagat tcagaaagaa tagatgattt acaattaaaa
     4801 ggccttaaaa ttatacaaga tactaatggt ttttgttttg gtatagatgc agttttatta
     4861 gccaatttta ctaaaataaa aaaagatgcc aaagtagtag atttgggtac tggaactgga
     4921 attataccta ttttgatagc tggaaaaagt gaagctaaaa aaattattgg cgtggaaata
     4981 caagaagatg tatatgaaat ggcaactcgt tctataaaat taaatggatt agaagaaaga
     5041 gttgagatta taaatgaaga tataaaatac atagacaaag tcttagacat aaatggttac
     5101 catgtagtca catcaaatcc tccatatatg catattgatg gaataaaaaa tccaaatgat
     5161 aaaaaagcaa tatcaagaca tgaagtaagg tgcaatttgg aagatgtaat tagagctgca
     5221 tccagattgg ttatgcctag aggaaaattc ttcatgatac atagaccaac aagattggtt
     5281 gatataataa ctttagggag aaaatataaa ttagaaccaa aggttattca atttgtgcat
     5341 ccaagacctc aaaaagcacc gaacttagtt ttggttcaat ttgtaaaaga tggaaggcca
     5401 gagcttaaaa tattggaccc attgtatgtt tatggagaag atgggaatta tacaaaagaa
     5461 ttaaaagcaa tatataataa taaagatata ggagagttgt aaatgagtgg gaaattgtac
     5521 atatgtccaa caccaatagg aaacctagaa gatataacat atagaacttt aagaacatta
     5581 aaagaagtag acttgattgc agcagaagat acaagacata gtataaaact tttaaatcat
     5641 tttgaaatct caaaaccact aactagttat catgaacata ataaggattc aaagggagat
     5701 tatttgataa ataaactaat tgatggtgaa aatatagctc tgataagtga tgcaggtatg
     5761 cctggtatat ctgacccagg agaagagata ataaaacaag ctatacaaaa taacatagag
     5821 atagaagtat tgccaggtgc aacagccttt gtaacggctt tagttggctc tggtatggac
     5881 acacatagat ttgtttttga gggcttttta gatagagata aaaaagttag gaaagcacaa
     5941 ttggaagaat taaaggaaga aagtagaact ataattttct atgaatcacc acatagattg
     6001 aaggatacac taaaagatat gcttaaaatt cttggtaata ggaatatttc tataaataga
     6061 gaacttacaa aaaaatatca agaaataata agagaaaata tagaaactac cataaaaata
     6121 tttgaggaaa aagaaataag aggagaattt gtattaatag tagagggttt tcatggtgag
     6181 aagtcaaaga aagaaaatta tgatgggctt acagataggg aatatgtttt aaaactaatt
     6241 gaaagtggta tgaacaaaaa agatgcaata aaaatagttt gtaaagatag aaagttaaag
     6301 aaagatgtgg tttataaaca agttttagat ttataaaacc tgaatctgag gtgattttat
     6361 ggaaataggg aaaattataa tagagagttt aaagagggaa gatacacata aaatatttat
     6421 agaattagat aataagcatg aattagaaaa aataattcct aaaataagct gtatgaagtc
     6481 tgtaggtgaa tgtaaatatc atgtagtaaa ttgttttgaa cattctataa acgcattaaa
     6541 agaattagaa atagtattaa atgataagga tttttttcca atacatctaa gaaaacatgt
     6601 gtcaaactat ttaaacacat atattgaaga aggaataaat aagttacatg tattaaagct
     6661 gggaacattt ttacatgata taggtaagcc tgacagtatg accttagatg aaaccggaag
     6721 agttcatttc acaaatcatg aaaaaatagg tgctcaaata attgacaata tgggaataaa
     6781 gttagagtta tcaacagaga catatagact tataagtaaa tatgtaagat atcatatgat
     6841 acttttgtct ctatataaga aaaatgattt gagtaggaaa gaattaatta atgtatttaa
     6901 cttagtagat gaggacacta taggtgtaat aatgcttggg tatgcagata tagtgtctac
     6961 agtaaaatta ttgggcaaga gtggagaagt cagtgtgtta aagacatata tggaatatat
     7021 tttaacaaat tacttgtata agagtaatta tacacatgta taaatttagt taatataatt
     7081 gagttttaga tgattaattg aagtttgaaa tatacggatt tcaaaaacat aaaagaagtt
     7141 gtctttgttg taaaattatg aaagacaact ttttttatat caaaaattga aattttatta
     7201 aggatactta atggtctatt aattaataaa ccattagtat ttaatttata ttacaatatt
     7261 gattttgctt gtattggcgt tgatagtata acagaggtct tagtagaacc aattttcttt
     7321 atagtatcaa tcacattttc taactcgtac atatctttta caattacttt taaaagtaag
     7381 caatcatcac ctgttatatg gtgacattct acaatcctag ggtcctttgc agctgactca
     7441 ataaattctg tatatccatt gcttggaaga gaaatatgaa taaatgcctt tataactctg
     7501 cctaatgaat ctgggttgac aatagcttta tatccttcta taacaccaga ctcttctaat
     7561 cttttgactc tttctgaaac tgcaggagaa gttaaaccaa ctatttttcc taagtccttc
     7621 atagaaattc tcccatcatc ctgtaaaatt tctatgattc tgtaatctgt aacatccata
     7681 aataaacagt cccccttaaa taaaaataat taatgctata aaactttttt agaatctatc
     7741 atttgtgttt ttaaatacca aagatttcta gataaatcaa ccttataaat gtgtggtttt
     7801 gaaagtcttt tgtattgttc ccagatagta cttaattcat attgtacatg attttttatt
     7861 tcaagaacag cttttttatt atatttgcat ctgcctttta tatacaatgg tttaagaagc
     7921 tctttaactt tgtaatttgt aaataccttc gttttccatg tataagtagg atggaagatt
     7981 tctaaaggtt tagactcatc tataacttca tcatgtaaca taatcaaatc tgcctctgcc
     8041 ttattgtctt cgttatatat tcttataact ttcttgtaac caggattatt tattttttct
     8101 ggattctcag aaatctttat cttaggttca agaactcctt tttcacaaga tgcagctaat
     8161 ttataaactc ctccaagaga aggtgaatcg aaagatgtaa tgagctttgt acctactccc
     8221 catgaattta tagtagctcc ttctgcttta agtgatgtta tggtatattc gtctaggtca
     8281 ttagatgcag tgatgctgat atctgaaaag ccagcattat ctaattgttt tttagcttct
     8341 ttagataaat aagctaaatc tccagagtca agtcttatac ccataggttt gtatcctttt
     8401 tcagaaatat ttttgaatac ttttattgca ttaggaactc cactgtttaa tacatcataa
     8461 gtatctacaa gtagtaggca tttatctgga taaacatcag catatgcttg gaatgcttca
     8521 agttcattat caaatttttg tacccaactg tgagcttgtg taccaattat aggtatatca
     8581 aacattttcc ctgctagtac gtttgcagtt ccagcacaac caccaactac agcagcccta
     8641 gccccatata tccctgcatc tggaccttgt gcacgacgta atccaaattc aaatacaggg
     8701 tctccttgag ctgcaaagca aactctagag gctttagtag caataagaga ctgaaaatta
     8761 actattgtta acaatgctgt ttcaataagt tgagcttgat ataaaggtgc cttaacagta
     8821 attaatggct cattagggaa catgatagtt ccttcctcaa cagcatatat atctcctgtg
     8881 aatttaaatt cttttaaaaa ttttaagaac ttgtcagaaa ataaatttaa gttttttaag
     8941 tactctaaat cttcatctga aaaatgaaga ttatctatgt attcaacaac ctgatcaata
     9001 ccacaaacta tagtataccc tccatcacaa gcgttttttc taaaaaacat atcaaataca
     9061 acaatgtctt catgaatatt cttttcaaaa tagccattta acatagtaag ctgatataaa
     9121 tcagtaagaa gtgttagatt tctcattatt tctctcctta attattatta aatattaaaa
     9181 attgtaaaaa ctcccacact tatactaaaa cataatatag tacaactttc aagtataaag
     9241 tattacctaa ctatcataaa attatttaaa gaggaggatg attataatag gaaaaatatg
     9301 gttttatatg gtatcgatag gaataatagg aagcttgatt tctaaaaata tgggtgaatt
     9361 aaataaagtt atattaagtg aaacatcaaa aggtatagag tttgcaataa gtctagctgg
     9421 tatcatggca ctctggatgg ggataatgaa tatcgcaaaa gaatcaggtt taattgaaaa
     9481 gataggtcaa aaactaaatc ctataatgag aagattattt ccttctattc caaaaggtca
     9541 taaagcaatg tcttatatag ttatgaatat tgctttaaat atgttgggtg ctggaaatgg
     9601 tgcaacagca tttggtttaa aagcaatgag tgagcttcaa actttgaata acaagaaaga
     9661 tacagccact aatgatatga ttatgtttat ggtaatcaat atatcatcta tacaaataat
     9721 tccatttacc ataatcaaac taaggatgga tatgggggct caaaatccaa gtgaaataat
     9781 ttttacgact ttatttgcaa ccataatatc tacagcagta gcaataataa catgtaaatt
     9841 ttttcaaaga agatatagat aaaggggatg tagatacatg gagatatttt caaacttact
     9901 tataccaata ataattctgt acatagtaat ttatggtaaa tataaaaaaa tagatgtgta
     9961 tgatagtttt gtaaaaggag caattgatgg attaaaagct gcatgggata tcctaccata
    10021 tataataggt atatttttgg caataggaat attcaaaact ggtaaaggtc ttgatatgtt
    10081 agaatggcta tttacaccaa tagcaaatat gatgagtata ccaaaagaat taataggtct
    10141 aataagtgta aaacctttat ctggaagtgg tgctttaggg atgtacagtg aacttgcaaa
    10201 tagagttgga ataggaagtt tagtagaaaa aatgggtgct acgattgtag gttcttctga
    10261 gactattttt tacacaatgg caatatacta tggaagtctg aagataaaaa atactagaca
    10321 tacattatca tgtgctatga ttagccatgt tgcaggtgtc atagcagctg tttttatttg
    10381 ctatgtaata tttgtataat ttgttgacaa tatgggaaaa attttataat atagtgatta
    10441 tatagaaaca aatagtaata caaattacaa gctatgaaaa gaagagtaaa taaaggtttt
    10501 ttctatcaga gagctaggtt aggtgaaagc tagtgtcaaa agctttattg aagatggtct
    10561 tggagctttt tatctgagca agtgtgctag ggtaaaacgg ttggacacgt tatagtctac
    10621 taaggtatct ataaaatgtt tctacatttc atgtgaaaca taactattat agatgaatta
    10681 gggtggtacc gtgaataatc tcgcccctat gttaactcat aggaggcgat tttttattat
    10741 ttaaatgaaa gaatcatatg attacgaacg ataaaaaatt aggaggtaaa taacatgagc
    10801 aaaccgagtt tttatgtaac aacaccaata tactatccaa gtggaggatt acacatagga
    10861 catacttatt caacagtagc tgcagataca atagctagat tcaagcgttt ctgtggatat
    10921 gatgtaaagt tcttaacagg aacagatgag catggtgaaa aaattcaaaa gaaagccata
    10981 gaacaaggaa tgtcagagat agagtatctt gatggaatga taaaagatat aaaggcctta
    11041 tggaatacta tggatatatc ttatgatgat tttataagaa ctacagaaaa aagacataca
    11101 gacataatac aaaagatatt tactaaacta tatgagcaag gtgatatata taaaggtgaa
    11161 tatgaaggta gatactgtac tccttgtgag agtttctgga cagaatctca attactagaa
    11221 ggaaataaat gccctgactg tggaagagaa acatatttag taaaagaaga atcttatttc
    11281 tttagattat ctaaatatga agacagatta aaagagttat ttaaagatga tagtttctgt
    11341 tttcctgctg ctagaaaaaa tgaaatggtg gcaaactttt tagacaaagg attagaagat
    11401 ttaagcgtaa ctagaacgac ttttgactgg ggtataaaag ttccttttga tgaaaaacat
    11461 gtaatttatg tgtgggtaga tgctttatgt aactatataa cagcattagg ttatatgact
    11521 gataatgatg aagaatttaa aaaatattgg cctgccaatg ttcaaatagt aggtaaagaa
    11581 atagtgagat tccatacaat aatatggcca gcgcttttaa tggctttagg tctagaagtt
    11641 ccaaaacaag tatttggaca tggatggata ctatttgctg atgataaaat gagtaaatca
    11701 aagggtaatg tggtttatcc agaacctata atagaaagat atggaataga cacacttaag
    11761 tacttcttat taagagagtt tgcatttggg caagatggaa gttatactca tagaaatttt
    11821 gtaacgagaa taaattatga tttagcaaat gatttaggaa acttaataag tagaactgta
    11881 gctatggttg aaaaatacaa taatggtata ataccaacag caaaagtttc aactgatttt
    11941 gatgctgact taaaagaaca agctgtttca actagagaaa actttgaagc tgaaatggat
    12001 aaaatgcaat tccatgaagc attagagagt gtatggaaat tagttagaag aactaacaaa
    12061 tatatagatg aaactatgcc ttgggcacta gctaaagatg aaacgaagaa agatgaatta
    12121 gacacagttt tatataattt atgtgaatct ataagaataa tcgcaacact aataaatcct
    12181 ataatgaatg agactgctaa taaaatatat gaacatatag gaataaaagg tcaagatgat
    12241 ataactacat gggaaagtac aaaaacattt ggtcttattg gagaaaatgt aaaagtattt
    12301 aaaggtgaac ctttattccc aagattagat gtagaaaaag agatagaaga attaactaaa
    12361 atgttctctg ggaaacctcc agtagaagaa aaacctttag agcataaaga agaaattact
    12421 attgatgatt tagacaaaat agagcttaga gtagggaaaa taataagctg tgaaaaacat
    12481 ccaaaagcaa ataaattatt agtatcacaa gttaagattg gaccagaaac aagacaaata
    12541 gtatcaggaa tagctgaata ctataagcca gaggatttag taggaaaaga ggttacagtg
    12601 gtatgtaact taaaaccagt taaattaaga ggtgtagaat ctcaaggtat gatattagca
    12661 gcaggtgatg atggagaccc atatgtttta ccatttacac aaggggctaa agatggatgc
    12721 gaggttcgtt agtaggtaat taaatagtaa ggagattaaa gatgttattt gactcacatg
    12781 cacatttaaa tgatgaaagt tttgatgaag atagagatga acttattggt tcattaaaag
    12841 ataaaggtgt agatttggtt gtaaatccag gagcagatat agagacgtcg ataacagcaa
    12901 ttgaacttgc gaaaaaatac gactttatat attcagcagt tggggtacat ccacatgatg
    12961 tatcaaaact agatgataca gcaatagaaa ctctaagaaa acttgcaact gagaatgaaa
    13021 aagttgtagc tattggagag attggattag attattatta tgattattct ccaagagaag
    13081 aacaaaaaga gtggtttaag aagcaaattg aattagctaa tgagctaaaa cttccaataa
    13141 taatacatga tagagatgca catggagata cttttgagat aataaagaat actaaaaatc
    13201 ctgaaatagg atgtgtactt cattgttata gtgggaatgt agagttagct agagaatatg
    13261 ttaagatggg ttgttatata tcaattccag gcacggttac ttttaagaat aataaaaaaa
    13321 ctagagaagt agtaagagaa atacctctag aaagattatt catagagact gattcaccat
    13381 atatgtcacc agagccacat agaggaaaga gaaacaatcc ttcccaagta tcttttgttg
    13441 ctgataagat agcccaggaa aaagggatat cttatgaaga agtatgtaga gttacaaaag
    13501 aaaatgcaaa gaaatttttt aatataaaat agacaaatta aatcttataa tgatatatat
    13561 aataagtcat tataagtata ggatgagagt gcctcaaaat gagtttttta gttcatgagg
    13621 cactcttttt tgtatgaaat caaatatatt ttcatcattt caacaatgaa aaagaagttt
    13681 atcatatttt gagatagttt gtttttattt atttaattca tattttaaaa tatattttct
    13741 taacattgtt aaaaaagaat ttacaagaga ttcattagaa ttaactcaac tctaatattc
    13801 acttaactta agttgtttat tatattatta aagagaagta aacgaaaggt agattaagga
    13861 ggttgaattt tgtatacagt tgatagtact aagatattga taaatatgaa cttagagaaa
    13921 ctagaaaaga tatactcaat gataaaagat acatcaagta tttctataat taaagaacct
    13981 aacttggcta cagtaatggt aagagctaat gaaagtgtaa aaaacacaac atttaattta
    14041 ggagagatat tagttactga atgtagtgta aaggtagatg aaagcttggg ttacggaata
    14101 gtttcagaaa acaataataa gaaagccatt tatttagcag ttatagatgc agttttacat
    14161 agcaataaca gtaaatttga tgagttaaag aattacataa ataaaagtgt atatgaagag
    14221 aacttaaggt atgaacaaga gattattgat gaatttagct tgattaataa aacgaaagtt
    14281 caattcaatg ctatggatta aataggagga gaatcatggt aaattataca caagaaatat
    14341 atagaaagat gctagatagt gcttcatttc ctgggaaatt aaataatata gataatataa
    14401 atatagaaaa taatacaaat ctattgaatg gagcaattgg tatagcaatc actttattag
    14461 accaagaagt taccttctat atagaaaatt atactcaaaa agatataaaa aatataagag
    14521 cacttacaat gtcaaatcaa atagattata gaaaatcaga ttatatattt ttagatatta
    14581 attcagaagt ggatatatta cagattaaaa taggttcttt tgaatatcct gatgaaagtg
    14641 caactatagt acatcaagta aatgatttat caacgtactc tcaaactaag tatataaagc
    14701 ttgatttgag tggtcctggt ataaaatcta aaaatagtat atatataaat ggaattagag
    14761 aagaatttat agaaagatta tctagtataa ataaagatta tccaatagga atagatttga
    14821 ttttagtaga taaaaaagga gaaattgcat ttataccaag gtcatcaaaa ttaagttggg
    14881 aggtattata gaaatggctt atgtagcagt taaaggtgga gaagaagcca tattacaggc
    14941 taaaaatata cttgagtttt atagggtaaa aggagatagc ttgcctatag atgtaaagca
    15001 gattgaagaa caaatgtctt atgctgtaga caaagtaatg tctgaaggaa gtttatacaa
    15061 caaggaacta tcagcattgg ctataaaaca agctcaaggt gatatattag aagcctcttt
    15121 ctatgtaaga gctttaaggt caacaatgcc tagaattaca tattcagaac ccataaatac
    15181 agaagaaatg agaataaaaa gaagaatatc agctactttt aaagatatac caggaggtca
    15241 gtatcttggg gcaactagag actatgaaaa tagaatattg aatgtagaat tattagaaga
    15301 agatgaaaaa aagaatagac attttagaga tagttttata aatgaattag aaacagtaga
    15361 tgaaatccct gaatttacaa aaatatctaa tatatttaga aaagaaaatt tattacaaga
    15421 agaagtttgt gaaaacaaat tggaagaagt tattgatgat attacaagaa atagtttaag
    15481 atttccagtt tctagggcag caaagttaca ggcattaact agaggtgaaa gcggagtagt
    15541 atcaggtttt gcttatgcta ttgtaagagg ctttggtgat gaacatccat atataagtga
    15601 acttagaact ggcaatgtgt ttataaaaat aaaacatccc atctatgaag atgaagaaat
    15661 aacaataggt gatatgttgg ttactgaatg tgaaatagtt tcaaaagcat cgcaaaataa
    15721 gactgaaaat tctaaaaata attcggaaga taaaaataaa atgtctttag gatatggtct
    15781 ttgtatgggg aacaatgaga ataaggctat atctatggct atactagaca aatctttgga
    15841 gccaaatagt gaaaaactag cacaagacga agaatttgta ttgcttcata tagatggaat
    15901 agattcatta ggatttatat ctcactttaa gcttcctcac tatgtagatt ttaaagcgga
    15961 tgtagaaaga ataaaaaagt ttgaggaggt aagtttaggt gatatataac tatggttttt
    16021 tagacgaaaa cacaaaaaaa gaaataagaa gaaagatatt aaaagcaata tcaatacctg
    16081 gttatcaagt tccctttggt tcaagagagt tgcctatagc taagggatgg ggtactggag
    16141 gtttacaatt aacactatca ttaattggta aaaatgatgt agtaaaagta attgaccaag
    16201 gaagtgatga ttctacaaat gcttgtaata taaggagctt tattgcaagt gtaagtaatg
    16261 tagaaaccac aaaagataca ttagaagcta cattgattca aacgagacat agaataccag
    16321 aagaaaaact taaatctaat caaatactaa tatttcaagt accaatacca gaaaccctta
    16381 gaatagtaga acctagtgaa gtagaaacaa gaagaatgca ttcagaagaa gattatagta
    16441 ggatgtgggt atatctttat gaagatatag ttagatttaa tgatatatct atagcagttg
    16501 aatatccatg taaagtaaat gatagatatt taatgaatcc atcacctata cctagatttg
    16561 atataaaaaa attaaatatg tcagacaatt tattcttgtt tggtgcaggt agagaaaaaa
    16621 gaatttatgc tattcctcca tatacaaagg tagaaccttt agagtttgag gattataagt
    16681 ttgaagagga aaagtttgaa ggaaaatact gtagtttatg taacagtaca aatacatttt
    16741 tagatgaagt atatgacagt gacactaatg aaaagtacta tagttgctca gatacaagtt
    16801 attgtgaaaa agttagatta aaaaataaca gtatagatgt gacaatagga ggtacttgga
    16861 atgagtaaaa taaatgactc taaaagatta gaaaatatag acaagcaagt attaatagga
    16921 agaaatatca atcttattta tggagatggg tgtgaaaagt gttttgaaag cacaggatat
    16981 gaaagcaata atatatgtaa gtattgtggt tctatagttg catgtaataa tgtaaattta
    17041 gaactttatg aaggagaagt ccttggaatt gtaggtgaat ctggttcagg aaaaagcact
    17101 ttattaaaaa tactgttttt ccaagaacat gcaaatagtg gagaagtata tatatcccat
    17161 tacaataaag acacaaatat actagagctt tcagaccaaa aaaagagata cataaagaat
    17221 cattttatgg gtattgtgta tcaaaatccc caccttggtt taaatttaga ctttagtagt
    17281 ggtggtaata tagcagaaaa attattgatg gcaaatttat ataatgttga aaaaataaga
    17341 gatagaggca aagaactttt aataaaaact aatatacctg tagaaagaat agaccataaa
    17401 ccaaaatact ttagtggggg aatgcaacaa cgagttcaaa tagcaaaagc tctttcaaat
    17461 aaccctccaa tattgctatt agatgaggtt acaacaggtt tagatgtttc tgtgcaagcg
    17521 gaagtattgg atttaataag agaaatccaa agagaattta agatttctat gatagttgta
    17581 tcccatgact ttgatgttat aaagatgctt gctgatagga caattgtaat gaaaaatgga
    17641 agtgtaattg agtctggtct tacagaccaa ataatggagg acccacaaca cccatatact
    17701 cagcaactta taaattcatt gctataaata tcgtttgtaa ataagcaaaa tgggggtttt
    17761 taataaaatg aaagaaacta tacttgaagt aaataatttt agtaaagact ttgagttaca
    17821 tgcattgaac aagactataa cggcatgtag taatataagt tttgaagttt caaaaggtga
    17881 gtttttagga ataataggta aatctggagc aggtaagtct accatattaa aaagtatcta
    17941 taaaacatat ataccaacaa ctggagaaat aatttttaat tcagaaatat atggtaatgt
    18001 agacctggct aaaattggag accgagaaat gataaatctt agaaagaaag aaataggata
    18061 tgtatcacag tttttaaaga cacttccacg aataactgca attgaactgg tagtacattc
    18121 tttaattgag agtgggtttg aaaaggattg ttcgtatgat atggcaaaag atatacttaa
    18181 ccaatttgaa ataaaggaaa atttatggga tgcgtatcca aataattttt ctggtggaga
    18241 aaaattaaga ttaaatttag ctcaagctat ggttaaaaag cctagacttt tgttacttga
    18301 tgaaccaact gcatcacttg ataatcaatc taaaatatat gtaaaagaaa aaatgttgga
    18361 gcttaaaagt caaggaacta caatgatagg aatttttcat gatatagagt ttatggaaac
    18421 tgttatagat aagaccttta ctatgacaaa agggactata agtgaaagtg gggtagccta
    18481 gatgataaaa ctaattcata atgcaaatat tgtattagaa gatatgattt tagaaaatgg
    18541 tcatttaatc atagagggag atacaataaa aaaagtatca aatgataaga ttgattacgc
    18601 atttgacttt aatgagatag atgaaataat agatgcaaaa aacttatatg taatacctgg
    18661 tattatagat attcacagtg atgccattga aaaggaaata gagccgagac caagtacatt
    18721 attaccattt aatatggcat tttatgaact agataaaaaa ctacctgcaa atggaataac
    18781 tacagtttat cattctatat ctttagggga tggagtagga gttagaagta ttgataactc
    18841 tttaaagatg attaaaaata ttgattcata taaaaatata gatagtaaga gcataaatca
    18901 taaagttcat ttaagatatg aagtgttgta ttatgaaggt ttagaaaagg ttttagaact
    18961 attagatgaa aataaaatag actacttatc aataatggac cattctccag gacaaggtca
    19021 gtatacaaat ccaacatttt ataaagagta tgctactaaa gtgtggggag ttacagaaaa
    19081 ttatgtagat acatggttag atgatttagt aaatctgcat gataatttag attggaataa
    19141 aatagctaat attataggta tagccaaaac taaaaatata aatgttgcat cacatgatga
    19201 tgatacatta gaaaaaatgg atttcataaa aaatataggc ataaatgtat ctgaatttcc
    19261 tataactctt gaagttgcaa aacattcaaa gaaattgggt gttctaactt gtttaggtgc
    19321 accgaatatt gtaagaggta aatctcataa taacaattta aaagcaatgg atgctatatt
    19381 ggaagattgt tgtgacattg tgtgttcgga ttatcttcca tcagctatga taaagtctat
    19441 gtgtatagtt gcagaaagaa taaataattt aaataaagca gtcagtttat ttacctcaaa
    19501 tcctgctaaa gcagttggta tatatgatga aagaggtagt ataaaagaaa ataaaaaagc
    19561 agatttagtt ttagtagata ttgatagtga atatccaaag gttgtaaata ctattgtaaa
    19621 tggaaaaaca gtttataaaa gggaggtata aagattgcta acagagttac attgtcatac
    19681 aagtatatca gataataatt ttactactga agaaataata aaaaaagcag cagaaaagaa
    19741 tataaatatc ttagcaataa caaatcatga cacattatct ggattggatg aagctcttgt
    19801 gcttggagag cattatggaa taacaataat accaggtata gaaatttcag cctatgatta
    19861 taaaaataga aaaagagttc atattcttgg atataacata gatttaaaca gtcaagaaat
    19921 aaaaaatttg tgcaatccaa tggtatgtga cagacataaa gcatctgtta agatggtaaa
    19981 taaaattata gatttaggat acaaaatatc tttggaagat gtaaagaaat attcatcaaa
    20041 gactggaata tttaaacaac atataatgaa agctcttata gataaaggat atacagataa
    20101 tatatattca agtctatata aagaattgtt tcatagagga aacggcaagg tatatgtatc
    20161 tttaaaatat gtggattaca gagatgcaat aaaagctata aaaaattctg gtggaatttg
    20221 tgtgttagct cacccgggtc aaatggataa ttttagcgct attgaagaga tggtaaaagt
    20281 aggattagat ggaatagaag tatatcatcc atctcacaac aaagaactag aaaaagagtc
    20341 gctttcttat gctaagaagt ataatctagt ggtcacagga ggctcagatt accacggatt
    20401 ttattctcaa cataattatg aacttggaag caagagctta aataaagaag atttatttaa
    20461 gtttaggtta gctttaggag gggtattata aatgtctttt ttacaagtaa aaaatgtagg
    20521 taaaagttat ggacaagtta aggtgttaaa agacatatct attgatattg aaaaaggaga
    20581 gtttatttgt ttactaggtc caagtggttg tggaaaaagt acactgctta gaataattgc
    20641 agggcttgag gataaacatg gtggaaaaat aataataaat gataaggata tgactaattc
    20701 accacctgaa agtagaaatt ttggtatagt ttttcaatca tatgcattat ttccaaatat
    20761 gaatgtttac aaaaacatag cctttggact agaaaataaa aacataagta aatctaatat
    20821 tgataaaaaa gttaaagaag ttctagaagt tgtagaatta agtggatatg agaaaaaata
    20881 tccatcacaa ttatcaggtg gacaacaaca aagggttgca ttagctcgtg cgattgcttt
    20941 agagccagac tttttacttc ttgatgaacc tttatctgca ttagatgcaa aagtaagact
    21001 taaacttagg gagcagatta gaagtttgca tagaaaacta ggcattacaa ctataatggt
    21061 aacgcatgac caagaagaag ctctttgttt agctgataag atggttgtta tgaatagagg
    21121 agaaataata caagttggaa cgccaaagga ggtatataaa aatccagaaa caccttttgt
    21181 agctgatttt ataggaacaa taaattttat agatgatggt attaataaga tagctattag
    21241 accagaagat ataaaagtag agtctaatag agattctaaa gataaggata taaaagtggg
    21301 agaaatttta gatatcgaat ttagaggatt taactataga attacagttg agtatcgttc
    21361 taagcagatg aaattagatg tagtttccaa agttgcagaa caaatgaaac tgtgtatagg
    21421 ttctaaaata aactttaaga tacctaaaga aggaattgta caatataaat cagagggatg
    21481 tgcttaatag ctaggggtga ataaatgata acatcaaaaa ataaaagaag aataagtgat
    21541 agcacaatac aaaaatattt cttgattttt tcggtaattg tactaatagt atttatatta
    21601 tttccattag tatcattatt aaaaaatgca tttatggata caagtggaaa ttttatagga
    21661 atttcaaact ttagtaaata tgttgaaaat ccaagtctta tagcatcatt taaaaattca
    21721 atttttgtat ctacagtctc atctttaata tcactatgtt tagcatttat atattcatac
    21781 gcaataacaa gaacaaacat aaagtttaaa gaatttttta aaactatggg aatgtttcca
    21841 ctttttgcac caactatgtt atatggtatt tcacttatat acctttttgg aaataaggga
    21901 atctttacaa ccatgggtct ggaagtacca ctatatggtc cattaggaat aattatttct
    21961 cagattctat ttacatttcc acaagctttt ttaatattat ctgtagcact ttcgatggct
    22021 gattacagac tttatgaagc agcagatagc ttgggtgcta gtgaatttaa gaaattttgc
    22081 aaaataacaa ttcctggtat aaagtactca ttacttagtt cattctttgt atcctttata
    22141 cttgcattta cagattttgg agcagctaag gtagttggag gaaactacaa tgtactggct
    22201 actgacatat ataaacaagt agttggacaa tttaacatac caatgggagc tactgtttct
    22261 atggtaatgt taattcctgt actaatagca tttacattag ataagatggc aagtaagaaa
    22321 caaggtatga ccataactgc aaagtctatg ccatataaga ttaaggaaaa taagtttaga
    22381 gatagagtat ttttaatagt atgtagtttt ataacattgc taatttttat tttaatattc
    22441 gtttcagtta taggttcagt tataaagtta tggccatata atttaagctt tacaatggaa
    22501 cactatacat ttaaaggtat tttgggaagt ggaataaaaa catatttaag cagtttgaaa
    22561 atatcaactt taacagcaat atttggaact atatttgtat tttttagtgc ttatatgata
    22621 gaaaaggtgg ataagtttcc taaattaaga caaacagctt accttttatc aatgatacca
    22681 atggccttac ctggcttagt tttaggtata tcatatataa ctttttttaa ctcagcaagt
    22741 aatccattaa attttttata tggaagtaca gcaatattag ttatagtaaa tgtagttcat
    22801 ttttattcag tttgttttat aacctcaaat tcatctttaa aaatgttgga taaagagtat
    22861 gaattagttg caaaatccat aaatattcca ttctataaag tattttttaa tataacagtt
    22921 ccaatgtcta taacatcaat acttgaaata gtagtatatt attttgtaaa ttcaatggtt
    22981 actgtttcag cattaatatt tttatataca cctcaaactc agactgcatc aatatcaata
    23041 ctaaagttag atgagatagg atatatagga ccatcagctg ctatggcagt attagtgctt
    23101 ttaacaaata taatagtaag acttttgtac gaatttgtaa caaagaaatt aaaaaataac
    23161 acacaaaaat ggcagcaaaa agatgttgca taggggaggt aaaaatgaaa tttaagaagc
    23221 tagtttcttt aggagtatta tcaacacttt tattaagtgt aataacagga tgtagtactg
    23281 attcatcagg ttcagattca aagtctgata gtaagacaaa aggggattta acagtttaca
    23341 cagcaattga agaagatagt atagagccat atttagctac atttaaagag aaatatccag
    23401 atattaaatt aaatattgtt agggcatcaa caggagatat aacagcaaga ttattagcag
    23461 aaaaggataa tcctcaagca gatgttgtat ggggagttgc agccacaagc ttattggttg
    23521 cagatgacca ggggatgtta gaaccatatg ctccaaaagg ttctgaagaa atagagtctg
    23581 catttaaaga tgataaagaa gttccttctt gggttgggat agatgcttgg atgacaggta
    23641 taacagtaaa cactaaagaa ttaagtgata agaacatccc agttcctagt tcttacgaag
    23701 atttaataaa gccagaatat aaaggtctta tatctatgcc taatccatct tcttctggta
    23761 cagggtactt aacagtatca gcccttatac aaattatggg ggaagaaaaa gcatggcagt
    23821 atatggataa gttacatgag aatattggtg tatacactca atctggttca gctccagcta
    23881 catcagcagc ttcaggagaa tatcctattg gtatatcttt tggatataga ggtataaagt
    23941 taaaagagga aggctatcca gtagaagtag tatttccaaa agaaggttct ggatgggata
    24001 tagaagcaaa tgctcttgtg aaaaaagata atataaaaga agcatcaaaa gtatttttag
    24061 attgggctat aagtaaagat gcaatgaacg aatactctaa aaactatgca gttactacta
    24121 tttctacagg aaatccaata ccagaaggat tccctaaaaa gccattagag caaatgatag
    24181 ataatgattt aaaatcagca gcaaaaaata gagaagatat actaaataaa tggatatcaa
    24241 aatatgatgg taagacagaa aaagagagtt aagtaaaact atacaaatgg agtaaaaaga
    24301 aaaatttttt ttaagtagat tttattatta taatataagt tgagaataat ataggtcaag
    24361 aaaagtgaat attctataaa aatgtataga gtaagtatac cattcagttt gaatggtata
    24421 ttttttattt ttagagatta atttagaaat agatatacta cagtttaaaa tagtatattt
    24481 taatttcatt attaaagtat agatgttata tataaagtaa ataagatatt aaataattat
    24541 aaactaaagt aaataaaata ttgagcgatt attaaaaaga tatatatata atttaatttg
    24601 agcagtttgt tatatattat aaaaaaagag aaaaataaaa ggtaaattgt ttctggataa
    24661 cttaaaattg gaagtaagaa tatttaacta gagaagaatt atttaagttt aggttagctc
    24721 taggagtagc tgattttata ggaacaatag attttatgga tgatgatata aacatggtag
    24781 caattagacc agaagatata agggtagaat ttaatagaga tttcaaagaa attatagacc
    24841 tcaaactcag accgtatcga tataaaaact aaagttagat gatatagtgt tgtagatagg
    24901 accatcagct gttatggcag tattagtgct tttaacaaat ataatagtaa aacttttgta
    24961 tgaattgata ataaaaaaat taaaaaccaa gacataaaaa tggcaacaaa aagaagttga
    25021 ataagggagg taaaaatgaa atttaagaag ttagtctctt tgggaatatt atcaacactt
    25081 ttattgagtg taataactgg atgtagtaat gtttcatcag gttcaaactt aaagtctaat
    25141 aataagacaa aaggagagtt aacagtttat acagcaattg aggaagatag tatagataca
    25201 tacttagcta catttaaaga gaaatatcca gatattaaat tgaatgtact tagattatca
    25261 gtaggaggta taacagcaag attattagca gaaaaagata atcctaaagc agatgtgtta
    25321 tggggtgttg cagctacaag tttgataatt ttagatgaca aagaaatgct agagccatac
    25381 gctccgaaag gctttgataa ggtaaattct gcatttaaag atgataagaa agttccttct
    25441 tgggttggaa tagatgcttg gatgactggt ataacagtaa atactaaaga attaaaagct
    25501 aaaaatatat cagctcctag ttcttatgaa gatttaataa agccagaata taaagatctt
    25561 atatctatgc ctagtccagc ttcttcagga acaggatatt taacagtatc agaactcata
    25621 caaattatgg gtgaagaaaa agcatggcag tatatggata aattgcataa aaatattggt
    25681 gtatacactc agtctggttc agctccagct atattagcag cttcaggaga atatcccatt
    25741 ggtatatctt ttggaaatag aggtataaag ttaaaaggtg aaggttatcc agtagaagta
    25801 gtatttccaa aagaaggttc tggatgggag atagaatcaa atgcacttgt gaaaaaagat
    25861 aatataaaag aagcatcaaa agtattttta gattgggcta taagtaaaga tgcaatgaat
    25921 gagtattcta agaattttgc agttactaca attgacacgg gaaatccggt gccagaagga
    25981 tttccaaaga atccattaga acagatgata gataatgatt taaaatcagc agcaagaaat
    26041 agagaggcta tactaaataa atggatagaa aaatatgatg gaaagacaga aaaagagagc
    26101 taagccttgc aataaaattt agtacaaaaa gcgcctagaa tataagtttt atatctaggc
    26161 tcttttgata tatttattta aaatgcatat ttctatataa aaataaatag tttagtacct
    26221 tgattaaatt aaataaaaac cttaaaataa agagatgtaa agaaaaacta aaaacgaata
    26281 aaaggtgaat ttatatgata aaagaaataa tagtagtaga gggtagagat gacgttacag
    26341 cagttaagag agcaatagat gcagaactta taactacagg tggatttgga tttccaaaag
    26401 gtgtaatgga gcgtataaaa gctgctaatg aaagacgtgg tgttataata tttacagacc
    26461 cagattttgc aggtgaaaaa ataagaaaaa aaatagcatc agaagttcca ggatgtaaac
    26521 atgcatttct accgagagag gaagctaaaa aggatggaga tataggtatt gagaatgcta
    26581 ctcctcaaag tataatagca gctctgaata aagttagaac tgaaaataca gaaaaaagag
    26641 atgaatttaa gcaagttgac ttaattagaa atggtcttat aggtaatgaa gaagcatcac
    26701 ttagaagaga tgcacttgga aaaatacttg gaattggata tggaaatgca aaacaatttt
    26761 taaatagatt gaataattat ggagttgaaa gagaagaatt tatagatgca ttaaaacaaa
    26821 tctaaacgta atgtttaatg tatgaaaaat atgtatataa aataaattgt ggaattacgg
    26881 ttaatttaag atgaattatt tataatatac accttatttt aaatcaatgt aaatacatat
    26941 aaataagtat aattaataaa attaaatatc aaaataagtt aaaaaggagt aaataatgga
    27001 tagactatct tcacataatg caacaaagga agtagtacaa aaatataatt ttaaattttc
    27061 aaagtcttta ggtcaaaatt tcttgataga tagtaatata attgataaaa tcttatctgg
    27121 agctagaatc acaagaggag ataatatcat agaagtagga cctggtatag gaactcttac
    27181 tcgtgagatg ggtaaaatag cagaaaaagt agtggctata gaaatcgata gaaatttaat
    27241 tcctatattg aaagatacct tgtcagattt agataataca gaggttgtaa atcaagatat
    27301 actaaaagta gacatacagg aattagtaaa agataaatta aatggtgggc cagttaagct
    27361 tgtagcaaat cttccatatt atataactac tccaatagtt atgaaatttt tagaggaaga
    27421 catacctgta acagacatag tagtcatggt tcaaaaagaa gttgcagata gaatgaatgc
    27481 tattccgggt actaaagatt atggggcatt atctatagct gttcaatact attgtgatac
    27541 agagattgtg gcaaaagctc caagacatat gtttatacca caaccaaatg tagattccac
    27601 agttataggt ctacatgtaa gagataaaag aaaatatgat gttcataatg aagacatatt
    27661 ttttaaaaca gtaaaagcat cctttggaca aagaagaaaa actcttctta attcgttggg
    27721 aggtcttggt tttcttaata aagatgaaat aagagaagta ttaaaagaag ctaatataga
    27781 cgaaaaaaga aggggtgaaa ctcttagtat agaagagttt tcagttcttt caaatataat
    27841 aaatacaaaa gtatcttcta aatagaaggt acttttttta attttgttaa catatattgt
    27901 ttagagaaac tgtgttaagg ggggattgca gtgggttcta aaagaaagtt taaaagagac
    27961 tatataatac tagaagctaa agacataaac tttagataca aagaacgagt actgccaaaa
    28021 gcttttgcaa aagttgaagt aaatgatgaa aaagcaatta ttgcattata tgtagaaaat
    28081 ctaaaatatg ttaaagatgg gtataaagca gtagcaataa aagatgacca tggattaata
    28141 gacttaggaa atataatttt aaatgaacaa ggaagaggtg aatttgtttt agatttagaa
    28201 gattatgatg atgagataaa aggtattgca ttattgtatg aaagaaatat acctttaatt
    28261 ggatttaaag gaaataagct tgaaaattat gaggacatat tatttcaaga ggtagaggaa
    28321 gaagaatatg aagaatatga agagttggaa gaagaagacg aagagataga ggagaatgag
    28381 gaaagtgata gagacgaaga tagtgaagaa gaatatatta tagaagaata tgatgaagat
    28441 gagtatgaag actattggga agatgatgaa gatattgaag aaggagagtt aaaagcaaga
    28501 acggaagtag aagattctga tgatgaggaa atagaagagt tcaataatta taaggaaata
    28561 gaaaattata atagggttaa agtacaggaa gaatatatag acatagaata tgatgaagaa
    28621 gaagaggaag aagaagtttt tgaagtaaat agagaagaag ataggtttgt ttcctcaaaa
    28681 cctactaaat caaagaaagt tcaaaaagat cagaataata ttgaaaaaat aaaaagagct
    28741 aatggagtaa gtcaaggaga gagtggaaat aaacaaacca gtacattact tatgccaaga
    28801 caaataaaaa aaggtttgaa attatttaaa gaagtaaaac cttttgtaac agattatata
    28861 gataagacaa gatggtggaa aatagagata aatcctacaa cactgtgtgg atatacaatg
    28921 ccttatttag gatatttaaa cgtattgaat tacactatgt atagtgatgc agttttacat
    28981 tcatataaat acagacacta tttatttgga gttcagtatg atgaatataa taagagaaaa
    29041 cattatattt atgctatccc aggaaataga aatgaacagc cagacaatgg aagcacagga
    29101 tttttaagat atcaagcttg tgataataga acaaatagtt taggatattg gctatgtttt
    29161 atagattcta gacaaagaaa tatagttagg taaaaataat aaaaatgaaa aaatttagac
    29221 tcaattctta ttttactgaa aaaattaatg aaatgtagta caaaacttta aaaactattg
    29281 ataatattta aatattacac tacaatatat cttgaaatac ctattatatt atggaggaaa
    29341 attatgataa acgagcaaag aattttaaat gagtttcttg aattagtaca gatagatagt
    29401 ttatctttaa aagaggggaa tgttgctaaa gtattagtta aaaaattaga agaaataggt
    29461 tgttcagtag taatagacaa tgctggtgaa aaagcaaatg gagaaactgg taatataata
    29521 gctacattaa aaggaaataa agaaggaaag aaaatattat ttagttcaca tatggataca
    29581 gtaactccag gtataggggt aaaacctata gtggatgaag caaatggaat aataaaaagt
    29641 gatggtacta caatattagg ttctgatgat aaagcaggta tagcagctat attagaaggc
    29701 ttaagatata taaatgaaaa taacatagaa catactgata tacaagttgt attctctata
    29761 tgtgaggaat gtggattagt tggagctaaa aatttagact atggaaaaat agattctgaa
    29821 tatgcattta tattagatag tggtggttct ccaggtgaaa taatagtaaa agctcctgca
    29881 caagatgtaa taaatgttaa gatattagga aagactgctc atgcaggtct tgaacctgaa
    29941 gctggaataa gtgctataat ggtagctgcc agagcaatag aaaatatgaa tttacttaga
    30001 atagacgaag aaacaactgc taacatagga attataaacg gtggaacagc tacaaatata
    30061 gtaacaggag aagttaatat agttgcagaa gccagaagtc taaaagaaaa taaattagat
    30121 gttcaaacta aacacatggt agagactttt gaaaaagctg cgaaagattt tggagctcaa
    30181 attgagatag atgttaatag agcatacaca ccaatagatg ttagtgagga ttctgaaata
    30241 ataaaacttg caaagaaggc tttttcaaac ttaggtatag aaggtcatac tgaatctaca
    30301 ggaggaggta gtgatacaaa tatattaagt aagaatggta tcgaagctat aactttagga
    30361 attggtatga aaaatgctca tacactaagt gaacatatag ctataaaaga cttatatgat
    30421 tctgctaaaa tggtagtgga gataataaag gaagcataaa tttaaataat agtgtataat
    30481 atatatatcg cctagcttaa gctaggtgat ttttcatttt atagaagatt gataatctct
    30541 attgaaagca aagagtatac atttgcatat aagagagtgt ttaatttatg ttcaaatgta
    30601 ggttcttaat aatatttaga ttgtttcata agggaggaat aaatatggaa acaaggtatg
    30661 aagaagcaaa taaaataaca atacaatcaa tactttggaa tatagtatta acaataatta
    30721 aggttatagc tggtgttatt ggtaattcta gcgctatgat tgcggatgga ttacattcag
    30781 catcagatat tataagttct ataggagtac taataggcaa ttatgtatct tctagacctg
    30841 gagatagaga gcataattat ggtcatgaga aagcagagac attagtatca tttgtgttat
    30901 caatattgct tattttcgtt tctataacaa taggtataga ggcaattaaa tctttattta
    30961 acttagatgc attaagtgtt ccatcaatat taccattagt agtatcagtt atttcaatcc
    31021 tgataaaaga gtatcaatat agaataacaa taaaagttgc taaaaagata aattcaccag
    31081 ccctaaaagc tgatgcttgg catcacaggt cagatgcttt atcttcagta gctgctttta
    31141 taggtatagg tggttctatt ttagggttta aaccattaga cccaattgcg tcagttgtag
    31201 tggctatatt tgtagctaaa gtaggaatta gtatacttat aagttctgtt aatgaattga
    31261 tggatgtttc agttgatgaa gaagagataa aagaattaaa atttattgta gcagatacag
    31321 aaggtgttaa aaatcttggt gatataaaga ctagaaaaca tggagctatg gcatatgtag
    31381 atttgactat atgtgtggat gaaaatttga cagttaagca aggtcatgat attgctacca
    31441 agcttgaaaa acatataata aaacatatgg aatttgtaaa aggtataaca gttcacgttg
    31501 aaccatgtac taattgccaa ggaaataagt gtaataatta attaaaactt aaaaaaaagt
    31561 gtaaaaagtt atataattgt tttatgatta taaactctag gggtggttaa atgagcaaga
    31621 aaagaaaact aaagaaaaaa gctgcaatat taataggagt agttgttttc tttataatat
    31681 actttatatc ctttagaata ggaataaata tggaaaagga taaaagtgaa gtgccaaaga
    31741 aggtagaaaa agaagaagaa gataataggt ctttaaggac tcaaataaaa gagaagaaga
    31801 aggtttatat atcagataaa aatatagaaa acataaaaat tgaagaagat atgtgggatg
    31861 aaataaagtt atttttctca gattttaaga aagtaagaaa tactacttct tcttacgaag
    31921 cagtttatga aggttattct gatgatggag ttaaattttc tactgacctt aactttttta
    31981 gagtatatac tgtaaataaa gaagaatatt ataaagtacc agttagttct aaggatgctt
    32041 ttaagaaact tttagatgag agtatatata cttcgtttga ccttttaagt cattataaag
    32101 attggaaaga ggttactata actcatggaa aagaaattaa aaaagttcat agatggaaat
    32161 ttgatgattt agcacataag atgatttcaa agagggttgt aggaaaagtt caacctgaga
    32221 aaagtaagga aagaagtgac tataatttta ctataaatat aaaaggtgat aattttgatg
    32281 taaaagttga tacaatggga aaagattatg taaaagttac ttctaagaaa aatgtatctt
    32341 actatgaggt tcatacaagt ttatttgatt accttaaaaa tgagatattt gaaattggaa
    32401 agaaataaga ctttaagaag gctatcaaat tagatatttg atagcctaaa ttattttata
    32461 tattattttt caaccaacaa gtctgcaacc ttataaattg gaccagcacc agcagttatt
    32521 actaaatcat tatccttaac attttcacgt aagtatttta ctatatcttc aaattctttt
    32581 atatagatgg catctacatt gttttgatat aatttctcaa ccaagtcctt agaatgtata
    32641 tctcctgggt ctttttccct agcagcatat atatctgtta tgataacttt atcagcagca
    32701 tagaatgcct ctgaaaattc acctaaaaga gattttgttc tagtataagt atgtggctgg
    32761 aagatacacc ataaagttga tttttttaat tttttggcag cagctaaagt tgcttttaac
    32821 tcagttggat gatgtgcata atcatctact actaaagcat tcttatagta ccctttagtt
    32881 tcaaatcttc ttccgacacc tttataaatt tttatatttt ttcttatagt ctctaagtca
    32941 ataccagaaa caagagctgc cattatggca gaagaagcat tgtatatgtt atgaagacca
    33001 tatacagaaa gttcaaattc tcctaaatct cttccttcat attctattct aaatattcca
    33061 tgaccactat tgtcaaagtg aatatctttt attacagcat cattgtcaga atctctgccg
    33121 tattttataa tagtagcttt aacatcatac aatatgtcat caatattttc atcatcgcca
    33181 tttattatga aatagccttc tgggggtaat aattttccaa atttgttaaa agaagccttg
    33241 atttcatcta ttccagagaa ataatcaaga tggtcttctt caacatttaa aactatagat
    33301 atctttgggt taaaattaag gaaactatct acatattcac atgcttcagt tataaagtgg
    33361 ttggaattac ctatcttaac attaccacct atcatactta agttaccacc aactagtata
    33421 gttgggtcta agtctgcata ttcaaagatt gtagataaca tagatgttgt agaagttttt
    33481 ccatgtgttc cagaaactgc tatagaattt ttatattccc tcatgatttg gcctaaaaaa
    33541 gttgctctgt tcattaccaa tttatttttt tctttagcag ccacaagttc ttcattgtct
    33601 ggatgaactg ctgctgtata aacaaccata tttacatcat ctgatatatt atcttttttc
    33661 tgaccaatat aaatagttgc cccttggtcc ctaagtttgt ctaataggta tgattcgttt
    33721 gaatccgaac ctgaaacttg ataaccttta ttgatacata tttcagctaa tgcactcatg
    33781 ctgataccgc caattcctat aaagtgtata ttcataataa aaccaccttt ctttttaatt
    33841 aagtcctaca atatgaacta tttctgtggt ataataatat aatgttcaat attttataat
    33901 taatatgcat ataatattat atgtatttta tttttgaata taataaaaca taagtaatat
    33961 tataccacaa taagaattgt tatgcattag ttagtttaac gttatataaa ggtacttgta
    34021 ggaggaaata ataatgaaat ttaaaagaac agagagaatt ggagcaatag ttaaaatact
    34081 gtctgataat ccaaataaaa tatatacttt aagttatttt acaaatcaat ttaatgcagc
    34141 aaaatcaaca ataagtgaag atttattagt tgtaaaaaat gtatttgaga agctacattt
    34201 aggtaaagtt ataactattt caggagcagc aggaggagta aaatatatac ctaaaacttc
    34261 tatagcagaa aatgcagagt tcttaatgga attatgcgag agaatatgtg acaagtctag
    34321 aatactatct ggtggttttt tatacttgat tgacctaatt tacgacccta caatagctgc
    34381 taagatagga aagatattcg catcaaatat tgagtatgta gatgcagatt atgttgtgac
    34441 aatggaaaca aaaggtatac ctatggcact tatgactgca aaagctatga atttacctct
    34501 agttataata agaaaagata taaaggtatc agaaggtcct acacttagca tgacatatgt
    34561 gagtggaaac agttctaaag ttgaaagtat gagtttgcca agaaaagctc ttaaaccaga
    34621 tagtaaagtt ataattatag atgatttcat gaggggtgga ggtactataa aaggaatggt
    34681 agaccttatg aatgaatttg gtgcagaggt tataggtact ggagtattca tatctacaac
    34741 gaatccttca gaaaaaatgg taaaagatta tatttcattg attcaattgg atgttaatgg
    34801 agataaaata gtagtagaac caaacttaaa gacttttaaa gatgaatata gaaatgaaga
    34861 tttagacgaa gaagaagatt cagaatttga atttgagata gatgaagatt aataaaaaaa
    34921 atatttagaa aaatatgtaa aaataaaaag aggatatccc tagttgttca tagaattatt
    34981 taaaaaacag tttatattaa tttattccag cgataataat tttaatataa attaatttct
    35041 gtcaaaatca aagggggata ttttggtatg aagataactg acgtaagagt aagaaaatta
    35101 acagaagaag gtaagatgaa atgtatagtt tcaataactt tcgataattt gtttgtagtg
    35161 catgatataa aagttataga aggccataat gggctattta tagcaatgcc tagcagaaaa
    35221 gtaggcgaag gaaatttcag agatatagct catccaataa atgcagaaat gagacaagtt
    35281 ttagaagatg cagttttaca agcgtatcat gaagcattag ttcaatggga agtagctgct
    35341 gaataataat aaatatataa aatggagaga gcccgaacat ttaggctctt tttaaatgta
    35401 gaatttctat taaaatatgt actttttagt aaaaaagtgc tatattatta gtgataatgt
    35461 atatgttgta tacaaattgt tagataaatg tattataatg tatattgatt aagagaataa
    35521 tacgaataaa attaaattag attgaatgga gtgtatcaat gaactttaaa gctataatcc
    35581 ttgctgctgg caaaggaaca agaatgaagt ctaaataccc aaaagttata cataaagtat
    35641 gtggaaaaga aatggttaac catattatag atgtttcaaa aaaatcaggg gtaaaagata
    35701 ctgtcgtgat tttaggacat gaagctgatg tagttaaaga aaagcttgca gaagaaatta
    35761 taatagccat gcaaacagaa caacttggga caggacatgc tgtaaagatg gctaaagaat
    35821 atattaatga tgaagataca atagttgtac tttgtggaga tactccactt ataaaagaag
    35881 agacactaaa gagactattt gaatatcata tagaaaataa atatcatgct acagttctta
    35941 caacaagagt tggaaatcca acaggttatg gtagaataat aagagataag aagggtgacc
    36001 ttcttaaaat agtggaacaa aaagatgcaa attcagaaga aaagatgata agtgagataa
    36061 actctggaat ttattgtttt aatggaaaga gtcttagaga agcactagat ttgctaaata
    36121 ataacaattc acaaggtgaa tattatttaa ctgatactgc taaaataatg agagataaag
    36181 gattaaaagt tggtgcattt gcaggttcaa ctattgaaga acttatgggc gttaattcaa
    36241 gagtagaatt atcaaaggca gaagaaatta tgagacgaag aataaatgaa tctcatatgg
    36301 taaatggagt aactataata gacactaact ctacctatat agaatctgat gttatgatag
    36361 gcaatgatac tataatatat ccaggtgtta tgttacaagg aaaaacaagg ataggttcag
    36421 attgtataat tggaatgaat tcatctataa caaattcaga aataggtgat ggtacagaaa
    36481 taaaaaattc aactataatt gatagtaagg ttggagaaaa ttctactgtt gggccatatg
    36541 catacttaag accaaagagt gacttaggaa ataatgtaaa aataggcgat tttgtagaag
    36601 taaaaaatgc tattatagaa gatggctcaa aagcatctca cctttcttat ataggagatg
    36661 cacatgtcgg taaaaatgta aatattggat gtggagtagt atttgtaaac tatgatggta
    36721 aaaataaatt taaatcaata gtaaaagaca atgcgtttat aggttcaaat tctaatttag
    36781 ttgcaccagt agttgtagaa gaaaaaggat atatagcaac aggttcaaca ataacacatg
    36841 atgtcccaga tggtgctttg gcaatagcaa gagaaagaca agttatcaaa gaaggatggg
    36901 tagaaaaaaa gaatcaaaaa gacgaccaaa gtaagtaatt atgtagttta ttattttggc
    36961 taaaaaattt agctcgaaat tattataaat tatattcatt agtattttaa aattttcagg
    37021 agggttacat aaatgaatac tagcggaagc gagattaaaa ttattgcagg taattcatcg
    37081 aaagagttag cacaaaaaat agctgactat ataggtgtat cagtactaga ttgtgaagta
    37141 ggtacattta gtgatggtga aatatgtgta aacatgaatg agacagtaag aggttgtgat
    37201 gtgtttgtag tgcaatctac taacagccca gtaaatgata acttaatgga gttattaatc
    37261 ttaattgatg cgttaaagag agcatcagca ggtagaataa cagcagttat tccttactat
    37321 ggatatgcaa gacaagacag aaaggctaag gcaagagatc caatcactgc taaattagtt
    37381 gcaaatttaa taactgctgc tggagcagat agagtattaa caatggattt acatgcagct
    37441 caaatacaag gatattttga tataccatta gaccacttac taggtggaac aatattagca
    37501 aattatttta atgaaaagaa aatagaagat ttagtagtag tatctcctga cttaggaagt
    37561 gttactagat caagaaaatt tgctaatact ttaaatggag aagttccaat agctataata
    37621 gataaaagaa gaccgaaagc taatgtatgt gaagttatga acttaatagg tgatgttaaa
    37681 ggtaaaaatg ttatactatt agacgatatg atagatacag caggaacaat agttaatgct
    37741 gcaaatgcac ttaaagagtt tggagcaaaa gatgtttatg cttgttgtac tcatggtgtg
    37801 ttatcaggtc cagctattga aagaattgct aattcagaaa taagtgagtt aatagttctt
    37861 gatactatac aacttcctga agagaaaaga atagataaga taaagataaa aacagtagct
    37921 cctttatttg gagatgctat aagaatgata ttctctaatg aatcagtaag taaattattc
    37981 taatttattg tatttatgag agttgtttaa aaggatataa accttttgag caactctttt
    38041 ttgattttat acttatggaa tgttattttt ttcttgttag aaaggtatat attattgtaa
    38101 aaagagatta tagtttaaaa ttatgtatat ttaagtaaaa taaacctaat aaagggtata
    38161 ttattcaaaa tattatgaat ataaaaaata ttacaaaaaa gtattgaaaa aattcagatt
    38221 atgtagtatt atgtaaatat aaataaagaa agaggtgttt ccaatgggaa ggttagaaga
    38281 tgaaccccta ataattaaat gattcagtca caatctaaag tgaatataaa aatctattga
    38341 aagtttattt ataagaattg aaaatagtat ctattctatc tttagtgttt gtgagagggt
    38401 tctggattat ataagattac tgtaaagagt aattttgcac aataagcata tctgtaaatg
    38461 aagagtttcg tttatataat gattgtggct gaatcataac tataatagat agaatgttta
    38521 taatagatga ttttataaaa tactatattg taatagcttt tagctttcaa ataaatatta
    38581 gcaaaggatg gaaatgacaa tgataaaact aaatgataat ttataaatat ctccttacga
    38641 tatataataa ttgtagggag atgtttcttt ttttgtatag cataattttt ctagaaattc
    38701 tgtttcaata tgtaaaaagt tggtatatat aaatagtata aacagtgttg ctaaaatatg
    38761 gtagatatta tataatataa gtggatatgt atatacatta tgagttatat aatttgaatt
    38821 taataaaata gaaacgttga tttatgttct gtaatgtggg caccttggag catattgagt
    38881 tagtggtgca accggctatg aaattgtatt tatttataaa tactattatt ttcatagctt
    38941 tttttattta aaaaatggtt atatgttaga aataaatttg gttagtacgt ttaaataatt
    39001 ttacttagat ttttaaccag atatattgta agtaagtatt aattaaaaaa tttaaggggg
    39061 aataaaaatg aagttaaaaa agaataaaaa aggtttcact ttagtggaat tattggtagt
    39121 aattgcaatt ataggtatat tagcagtagt ggcagttcca gctttattta gtaatataaa
    39181 caaggctaag gtagcaagtg ttgagtctga ttatagttca gttaagagtg cagcattatc
    39241 ttattattca gatactaata agataccagt tacaccagat ggtcaaactg gtttaagtgt
    39301 tttagagact tatatggagt ctctgcctga taaagctgat ataggtggaa aatataaatt
    39361 gattaaagtt ggtaataaat tggtattaca gataggtaca aatactgaag gagttacatt
    39421 aacagaggca caatcagcaa agttattgag tgatataggt gaaaataaaa tatatacaag
    39481 cgctacaaca aatagtttgg gaaatccatt aacaagtaat acaaaaatag ataataacgt
    39541 tctatatata gtacttatag ataatactgt gatggacaca acaaaatagt taaaacaata
    39601 tttttataaa aat
//
LOCUS       DAEHWO010000033        39523 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEHWO010000033 DAEHWO010000000
VERSION     DAEHWO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39523
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.033"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            31..1143
                     /locus_tag="KNP54_002014"
     CDS             31..1143
                     /locus_tag="KNP54_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBF0892915.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENI
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1397..3421
                     /locus_tag="KNP54_002015"
     CDS             1397..3421
                     /locus_tag="KNP54_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0892916.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGSGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3641..4327
                     /locus_tag="KNP54_002016"
     CDS             3641..4327
                     /locus_tag="KNP54_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBF0892917.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4422..5477
                     /locus_tag="KNP54_002017"
     CDS             4422..5477
                     /locus_tag="KNP54_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBF0892918.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5592..7148
                     /gene="murJ"
                     /locus_tag="KNP54_002018"
     CDS             5592..7148
                     /gene="murJ"
                     /locus_tag="KNP54_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBF0892919.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7194..8900
                     /locus_tag="KNP54_002019"
     CDS             7194..8900
                     /locus_tag="KNP54_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBF0892920.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8922..9995
                     /locus_tag="KNP54_002020"
     CDS             8922..9995
                     /locus_tag="KNP54_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBF0892921.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10007..10729
                     /locus_tag="KNP54_002021"
     CDS             10007..10729
                     /locus_tag="KNP54_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBF0892922.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10745..11902
                     /locus_tag="KNP54_002022"
     CDS             10745..11902
                     /locus_tag="KNP54_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBF0892923.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11905..12744
                     /locus_tag="KNP54_002023"
     CDS             11905..12744
                     /locus_tag="KNP54_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBF0892924.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12759..13934
                     /locus_tag="KNP54_002024"
     CDS             12759..13934
                     /locus_tag="KNP54_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBF0892925.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13963..14712
                     /locus_tag="KNP54_002025"
     CDS             13963..14712
                     /locus_tag="KNP54_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBF0892926.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14734..15642
                     /locus_tag="KNP54_002026"
     CDS             14734..15642
                     /locus_tag="KNP54_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBF0892927.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15690..16442
                     /locus_tag="KNP54_002027"
     CDS             15690..16442
                     /locus_tag="KNP54_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBF0892928.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16396..17763
                     /locus_tag="KNP54_002028"
     CDS             16396..17763
                     /locus_tag="KNP54_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBF0892929.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17769..18860
                     /locus_tag="KNP54_002029"
     CDS             17769..18860
                     /locus_tag="KNP54_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBF0892930.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18944..20857
                     /locus_tag="KNP54_002030"
     CDS             18944..20857
                     /locus_tag="KNP54_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBF0892931.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21056..21763
                     /locus_tag="KNP54_002031"
     CDS             21056..21763
                     /locus_tag="KNP54_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBF0892932.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22065..24176
                     /locus_tag="KNP54_002032"
     CDS             22065..24176
                     /locus_tag="KNP54_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBF0892933.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24374..25339)
                     /locus_tag="KNP54_002033"
     CDS             complement(24374..25339)
                     /locus_tag="KNP54_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBF0892934.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25624..26580)
                     /locus_tag="KNP54_002034"
     CDS             complement(25624..26580)
                     /locus_tag="KNP54_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBF0892935.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26948..27736
                     /locus_tag="KNP54_002035"
     CDS             26948..27736
                     /locus_tag="KNP54_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBF0892936.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27859..28329)
                     /locus_tag="KNP54_002036"
     CDS             complement(27859..28329)
                     /locus_tag="KNP54_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBF0892937.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28468..29112
                     /gene="uppS"
                     /locus_tag="KNP54_002037"
     CDS             28468..29112
                     /gene="uppS"
                     /locus_tag="KNP54_002037"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBF0892938.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29155..30060
                     /locus_tag="KNP54_002038"
     CDS             29155..30060
                     /locus_tag="KNP54_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0892939.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30375..31922
                     /locus_tag="KNP54_002039"
     CDS             30375..31922
                     /locus_tag="KNP54_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0892940.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31925..32323
                     /locus_tag="KNP54_002040"
     CDS             31925..32323
                     /locus_tag="KNP54_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBF0892941.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32363..34096
                     /locus_tag="KNP54_002041"
     CDS             32363..34096
                     /locus_tag="KNP54_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBF0892942.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34328..35539
                     /locus_tag="KNP54_002042"
     CDS             34328..35539
                     /locus_tag="KNP54_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBF0892943.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIVQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35732..35992
                     /locus_tag="KNP54_002043"
     CDS             35732..35992
                     /locus_tag="KNP54_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBF0892944.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36346..38058
                     /gene="ptsP"
                     /locus_tag="KNP54_002044"
     CDS             36346..38058
                     /gene="ptsP"
                     /locus_tag="KNP54_002044"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBF0892945.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(38850..39515)
                     /locus_tag="KNP54_002045"
     CDS             complement(38850..39515)
                     /locus_tag="KNP54_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892946.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
BASE COUNT        15773 a         4148 c         6911 g        12691 t
ORIGIN      
        1 atttcaaata atgctgtaga ttctaaactt atgaatagta ggattaaatc aatagatata
       61 ataagagggc tatcaatagc cctcatgata gtctgcaata atcctgggac ttggatgaga
      121 atgtatcctc aattaagaca tgctgtatgg catggtgtaa cacttgcaga ttttgcattt
      181 cctttttttg ttatatcttt aggtgttaca attccaatat caataaatag taaactaaaa
      241 aataataaat ccacactgag tataatactt agtatattca agagaagtat cttattgata
      301 ttatttggat ttttcttaaa ttacctagga aatcctgatt tagatactgt aagaatactt
      361 ggagtacttc aacgtatggg attagtctat tttgtgacta gtttagtata tttactacta
      421 aaaaaattaa atgttggaag tactgctaca ataattactt ttctatgtat atctacattt
      481 ataatagttg ggtactacat attagcaaaa ccttatggat ttgagctaga aggttctctt
      541 gcacagttag tggatttaca tttcttcaag ggacatttgt acaagccgga atttgaacca
      601 gatggttttt taactagtat agtagcaatt tcttcaggta tgttgggatg cactatggga
      661 tgtgtacttt taaaagaaaa cataggagaa tataaaaaat tctttaaaat actggttatg
      721 agcataatcc tgctaatagg tgcttttatc tttaatcagt attttccatt taataaaaga
      781 ttatggtcta gctcatttgt acttttaatg gctggcagtt atggtatatt actgtcaata
      841 ttttatttta tatgcgacat caaaaataaa agtaaaatat ttaccccaat aatagcactt
      901 ggaagtagcc ctatttttac atatatgtgc cttgaaatat tgagtcatgt tttttggaat
      961 gttccaaaac ttacgaacaa agtcgattat ccaactacct tggtagagtg gactacatat
     1021 gaacttataa caccttgggc aggtacaact tgggattctc ttatattttc tttattgtat
     1081 gtcctattct gggttatagt aatgtctata atgtacaaga aaaaaatatt tattaaaatt
     1141 tagtgcaata tttttagatg ataaagtctt tgatttgttc aaatatacgg aaactatcaa
     1201 atataatcaa aatttctcct cgataaaatt taaaaaccat gccataaaag attacaaaaa
     1261 gtttacaatt tgtaattttt tgtgctataa tgaaaaaaga tttacataat attgaattta
     1321 tgtaatataa aacaagctta agatgtatta aaaaagattt aaagatttaa agaaccaaaa
     1381 aattaggggg gatatgatga aaaaaacaac aaaattattg gcaacaggaa tgttgtctgt
     1441 agcaatggtg gcaccaaatg tagctttagc ggctgaaaat actactgcaa atacagaatc
     1501 taattcagat attaatataa atttacaaag aaaaagtgta gtgttaggaa gtaaatctaa
     1561 tgcaagtgta aaatttaaag aaaaattaaa tgctgattca ataacattaa attttatgtg
     1621 ttatgatatg ccacttgaag ctactttaaa ttacaatgaa aagacagatt catatgaagg
     1681 tgtaataaac tataacaaag acccagaata cttaaatgta tgggaacttc aaagcataaa
     1741 aataaatggt aaagatgaac agaaagtttt aaacaaagaa gacttagagt ctatgggatt
     1801 aaatcttaag gattatgatg ttacacaaga gtttataata agtgatgcaa attcaacaaa
     1861 agcagtaaat gaatatatga gaaaaacttc tgcaccagta aaaaaacttg ctggagctac
     1921 tagatttgaa actgctgttg agataagcaa acaaggttgg aaagatgggt ctagtaaggt
     1981 tgtaatagtt aatggagaat tagcagcaga tggaattaca gctactccac ttgcatctac
     2041 atatgacgca ccaatattac ttgcaaataa agatgatata ccagaaagta caaaagcaga
     2101 gttaaaacgt ctaaatccaa gtgatgtaat aattataggt gatgatggtt cagtttcaca
     2161 aaaggcagtg tctcaaatta aatctgctgt aaatgtaaat gtgactcgta ttggtggagt
     2221 tgatagacat gaaacatctt tacttatagc aaaagaaata gataagtatc atgatgttaa
     2281 taaaatatac atagcaaatg gatatgctgg tgaatatgat gctcttaata tttcatcaaa
     2341 agctggtgaa gaccaacaac ctataatatt agctaataaa gattctgtac cacaaggtac
     2401 atataattgg ttatcctcac aaggtttaga agaagcttat tacataggtg gtagtcaaag
     2461 tttatcatca aaaattatag accaaatatc taaaatagca aaaaatggta cttcaaaaaa
     2521 tagagtttct ggagcagata gacatgaaac aaatgcaaat gtaattaaga ctttctatcc
     2581 agataaagag ttgagtgcaa tgttagttgc aaaatctgac ataatagttg attcaataac
     2641 agcaggacct ttagcagcta aattaaaagc tccaatactt ataactccaa aaacttatgt
     2701 ttctgcatac catagtacaa acttatcaga aaaaacagca gaaacagtat atcaaattgg
     2761 tgatggaatg aaagatagtg ttataaattc tatagcatct agtttatcaa aacacaatgc
     2821 accaacagaa ccagataatt caggttcagc agcaggaaaa actgtagtga tagacccagg
     2881 tcatgggggt tctgattcag gggcaacaag tggattaaat ggtggagcac aagaaaagaa
     2941 atatactctt aatacagcat tagcaactac tgaatattta cgttcaaaag gtataaatgt
     3001 tgttatgact agagatacag ataaaacaat ggctttagga gaaagaacag cattatcaaa
     3061 tactataaag ccagatttat ttacaagtat acattacaat gcgtctaatg gatctggtaa
     3121 tggtgtggaa atttattaca aagtaaaaga taaaaatggt ggaacaacta agactgcagc
     3181 atcaaatatc ttaaaaagaa tactagaaaa atttaatatg aaaaatagag gaatcaagac
     3241 aagaacactt gataatggaa aagattacct atatgtgtta agaaataata attatccagc
     3301 aatacttgtt gaatgtgcat ttattgacaa taagagcgat atggataagt taaatactgc
     3361 agaaaaagta aaaacaatgg gaactcaaat tggaatagga atagaagata cagtaaaata
     3421 aaatagaaaa tattaaagca aaacatatca tctcctgtta taatgtaaaa tataacaaga
     3481 gatgatatat ttttgtaaag aatcaaattg tttacaatga tgtttcttgt attgataatc
     3541 tgctcattat tgagtataat atagaaataa gtcaaaaata agatagaaat aagttgaaat
     3601 taagaattaa aaaaattttt attccaatat ggaggtaact atgtctggat atactaatga
     3661 tgagtgtgaa atacctaaaa ttaaaagcta tccaggggca gataaagaaa ttgcaagtga
     3721 gattgactat agcatagtaa aaggaacagt tttattcgac ttgtaccaaa gaattatgga
     3781 tttagtttta tctataatag gacttgtgat aggtttacct ttaatagcaa tatttggaat
     3841 tcttattaaa atagaggaca aaggaccaat aacttataag caagaaagac taggaaaatg
     3901 cgggagaaga ttctatatat ataaattgag atctatgaga acagacgcag aaaaatttgg
     3961 cgcacaatgg gctgaaaaag atgatcctag aataactaag gttggaaagt ttattaggaa
     4021 aactagaatt gatgagattc cacagctgtt taatatatta aagggggaca tgggcttaat
     4081 aggtcctaga ccagagagac cgaactttac tgttcaattt aatgaggaaa tacctggatt
     4141 tatcaacagg ctcgctataa aacctgggct tacaggttgg gcacaagtaa atggtggata
     4201 cgaaatcact cctgaagaaa aacttaaaga agatatttac tatataaaaa ataggagtat
     4261 attacttgac tttaagatac tctttaaaac tgttaaagta gtattgacag gagacggagc
     4321 tagataattt taaaatatta gattactaat caatgaaaaa gctctttaaa aagagctttt
     4381 ttattgtcaa aaaatacaaa aaagaaaagg aatgagaact tatgattaaa aaaatttcta
     4441 ctatattatc gttagttttg ttaatctcta tttctagtac gataggagta tttgcagatg
     4501 caaatcccaa aagagaattg atagaaggga gtataccaga gatttcgaca gaattaaata
     4561 aaagagcatt taaggattct aaagaagtaa ttcttgtaaa tgaagagtca attgtagata
     4621 gtataagtgc aacaccttta gcatatgcaa aaaatgctcc aatagttgta actaagagta
     4681 aaaatcttgg tagagtaaca agaaattatc taaaagaact aggtccagag aaggttacga
     4741 tagtaggtgg tttaaaggca gtatctaaag atgctgaacg taatatagaa aaaatgggaa
     4801 tgaaagtaga aagaataaga gggaaagaca gatatgatac atctttaaag atagctagag
     4861 aaatgtatag aacagtagga tttgatgaag catttttact tagctcaaca acaggattag
     4921 agaacgccat atctgtatat tcttatgccg ctaaaagtgg aatgccaata atatgggcta
     4981 aagatgaagg gtttgaggaa caaattgatt tcttaaaagg caaaaatctt aaaaaaatat
     5041 atgcattagg tgattcaaaa gagtttattg cagagattga ttctaactta aaaaatatag
     5101 aaggaataaa gcaaataaat aagtcaagta caaatgttga tttaataaag aagttttatg
     5161 atgaaaaaga tataaagaaa atctatactg ctagattaga ctttggtagt agatctgatg
     5221 taaacgaata tatttctttg ggagtagtat cagcaaaaga aaatatgcca atactgattt
     5281 gtagtgataa cttaagtcgt gcacaagata aattcttgaa agatagcaat ataaatgatg
     5341 tagttgaagt tgggtataca gtaggtgatt atagtctatt taagagcata tttaatctaa
     5401 cattcttatc ttgtatagta ttaatactat tattactatt gattacattt agggcactta
     5461 gatatgagtc gaaatagttt ttgatttata aggaagcttt tcataggtta aatttactta
     5521 attagaataa tgtttataag cagttttaaa agttctactt ttagagttta aattagataa
     5581 ggagaaagaa gatgtcaaaa acagctaaag cagcattgtg gattatggca gccactatgt
     5641 tttcaaaagt attaggtttc cttagagaac ttgtacttgc aaatttctat gggacaggta
     5701 tgtatgcaga cgtatttgta ttaacattaa atatacctgg tttaatcata gcagtcatag
     5761 gctctgcagt tgctacaact tatataccta tgtactttga gacaaagaaa agactcggag
     5821 atgaaggtgc cttaaaattt actaataatg ttttaaatat atgctatata atggctatag
     5881 taatagctat tattggtctt ttatttacag agcaatttgt tacagtattt gcagcaggat
     5941 ttagaaacga ccctgctaag ttccaagcag caatattatt tactaaaata atgatttcag
     6001 gagttttatt cctgagtgga agtaagatat ttagttcgtt tttacaggtg aatgacagtt
     6061 ttgtaattcc tgggcttata ggaatcccat ataatattat aataatagca gcaatagcac
     6121 taagtgcagg taaaaatgta tggatactgc cagcaggagc actattggct atggcaagtc
     6181 agctattgtt tcaactgcca tttgcgttta agaagtccta caagtataag ccatatataa
     6241 atttaaagga tgagtccata aaagagttag tcaacctagt attgcctatg ttggtaggag
     6301 tagctgttgg acagttaaat atatttgttg accgattatt ggcaaccact ttgggtgatg
     6361 gaaagttgtc tgctcttaac tatgcaaata ggctaaatga gtttgttatg gcattatttg
     6421 ttacatctat aataacagtt atatatccta aactagcaaa aatgtctggt aaagataata
     6481 aagaaggatt tataagtact attgtaaaat cttcaaattg tattatattg gtggtgcttc
     6541 ctatatctat aggagctatt atattagcag agcctcttgt tagaatatta ttccaaaggg
     6601 gtaaatttga tgcgttatca acagacctta catctatagc gcttagatta tattcactag
     6661 gtttattggc ttgtggagta agagatgtct tatatagggc attttactct ctttcagata
     6721 caaaaacgcc aatgataaat ggaagtatag ctttaataat aaatatagtt cttaatttaa
     6781 tattgataag accattgggt catgcaggta ttgctatatc aactagtaca tcaaacataa
     6841 ttacagttat attattattt atatctctta aaaagaaaaa tggatatttt ggaggggata
     6901 aaattataaa gactggtcta aaaagtttgg tagcatctgg tgtgatggca gtagctactt
     6961 tattgatata taataatcta tatgcattta tgggttcagg aacaattaaa gaaattatat
     7021 cagttggagc tggagtatta ggtggagctt ctgtatatac tgtattgata gttttattta
     7081 aggtagaaga gatggattta gcttttgaat ttttaagaaa aggaaaacaa aaactactta
     7141 gaagatagat aattaccttg aaattttaaa ttagagtcag aaaggatgaa aatatggatt
     7201 ataagaataa ttatgagatg tggttaaatt ctccttattt tgatgaacaa acgaaaaatg
     7261 agctattaag tataaaagat gatgaaaaag aaatacaaga tagattttat aaaaatttag
     7321 agtttggaac aggtggttta agaggtataa taggagcggg aactaataga atcaatattt
     7381 atactgttag acgtgcgaca ctgggcgttt taaattatat catgaaaact caaggagaag
     7441 aaggtaagca aaagggaata gttatagcac atgatagtag atacatgtct agggagtttt
     7501 gtatagaagt agcaaagact ttaagtgctt atggtgtaaa ggcttatatt tttgaagaat
     7561 taaagcctac accagaactt tcttttgctg ttagatattt aaagtgtgct atgggaatag
     7621 taataacagc aagtcataat cctaaagaat acaatggata taaagtatat gactcagatg
     7681 gtggtcaaat ctgtatagat atggcaaatg atataatagc agaagttaat aagattgatg
     7741 attacagtac tattaaaagt atagattttg aagaagcttt atctaaaaat ttaataacta
     7801 tattagataa tgaagtagat gatgagttta taaaagctgt taagaagcaa gttttaagac
     7861 aaaatataat agatgaatac gggaaaaaat taaaaataat atatacacct attcatggta
     7921 caggaaataa gccagtaaga aaagtcttaa atgaatgtgg ctttgaaaat gtaatggtag
     7981 ttaaggagca agaattgcca gattctaatt tttcaacagt aaagtatcct aatcctgaag
     8041 aaaagtcagt gtttaatata gctattgaaa tggcaaagaa caatggcact gatttgataa
     8101 taggaacaga ccctgattgt gatagagtag gtatcgttgt aaaagattca agtggtgaat
     8161 atgtagtctt aaatggaaat caagtcggtt cacttttagt tagatatata ttagagagtt
     8221 tagttgaaga aaataaactt cctaaaaaca atcctacaat aataaaaact atagttacat
     8281 cagaactagg tgcaaaaata gcaaaggctt ataatgtaga ttgtttaaat actttaacag
     8341 gatttaaatt tataggagaa aaaataaaag cgtttgaaga aagcaatgat agaagtttta
     8401 taatgggata tgaggaaagc tatggttact taattggaac tcatgctaga gataaagatg
     8461 gtgttgtatc ttcacttatg atatgtgaaa tggcagcata ctattcttca aaaggtatga
     8521 acttgtatga agctttgata gatacatata ataaatttgg atactacaaa gaggacttaa
     8581 agtcagtaac tttaaaaggc atagatggaa taaaaaaaat aaaagagatg atgctttact
     8641 ttagaagtgt taaaatagat aatgtggctg atgtaaaagt agataaaatt ttagactata
     8701 aagatggtgt tgatgattta cctaagtcag atgtacttaa atttttactt gaagatggct
     8761 cttggatagc tataagacct tcaggtacag aacctaaaat taaattttac tttggagcaa
     8821 attcagacaa tcaagaagat gtagaattta agttgaacaa tttaatatct tatatattaa
     8881 atgtagtgga ttctatataa aaagctaagg ggagataaat aatgaaagta tacaatgtca
     8941 taatggctgg aggaggagga actcgtttct ggccacttag tagacaagaa gtacctaaac
     9001 agcttataaa tttaagtgga gaagatgctt taataaacga aactataaac agaatagatt
     9061 ctctagcaaa aaaagatgat ttatttatag taaccaatga gaagcaattg gaagctttaa
     9121 aggatatagt aaaagataaa tgtttggata gtaatatatt gccagagcca tgtgccagaa
     9181 atacagcagc agctataggt tttgcagcat ttaacataat gaaaaaatat ggtgatggtg
     9241 ttatgtgtgt atatccagct gaccattata taaaagatga aaaagaattt aaatctattt
     9301 tggaaaaagc tatctatata gcagaaaata atgataaact agtaactatt gggataactc
     9361 ctacatttcc atcaacagga tatggataca taaattttaa tagagaaaat actatagaag
     9421 atgttgcata tgaggtagtg gagtttgtag aaaaaccaaa ctatgaaatt gctaaagaat
     9481 atgtaaactc taaaaagtat gtatggaata gtggaatgtt cgtatggaag gtatctaaaa
     9541 tactagaaga ttttaagaga tacttgccaa aagtatatga aaaattagaa gatataagta
     9601 aatacttagg aacaaaagaa gaaatggaaa aaataaaaga aatataccca actatacaat
     9661 caatctctat agattatggt attatggaaa gaagtaatga tgttatagta gttcctggtg
     9721 attttggatg gaatgatgtt ggttcttggg attctctagg tgcaatatat ccaactgatg
     9781 atgaaggtaa tatcaaaaga ggtgaaaata ttactataga tactaaaaat tcaattatat
     9841 attcagatga caaattaata tcaacaatag gtattagtga tttgatagta gtatctacaa
     9901 atgatgcagt tatggtttgt agaaaagata aagctcaaga tgtcaaaaaa atagtagagc
     9961 agttaaaaga agaagataga caagaatata tgtaggaggt gttcatttga ttcctaaaaa
    10021 aatacattat gtatggtttg gtggtccaaa aggaaatata gaaaatatat gtataaattc
    10081 ttggaaagaa aagcttccag aatatgagat agtagagtgg aatgaaaaaa actttgatat
    10141 agagaaagaa ataaaaggaa ataagttttt ggaagaatgt tataaaagaa aactttgggc
    10201 attcatatct gattatacaa gaataaaagt actctatgaa caaggtggag tttatatgga
    10261 tacagatatg caaatattaa aggatataac tcctctttta gaaaataata ggctaatctg
    10321 tgggtatgaa gatgatagag agtatataaa tggtgctata ataggtgtag aaaaaggaca
    10381 tcctttttta aaagacttat tggagtatta tgaaaaagaa gtacttactt cttcattgtt
    10441 tacaatacca aagataatga ctcatcttat ggaaaagaat tataagaaga ttgacccaaa
    10501 taattatgaa gaaggaatac gtgtttacga caaagaatat ttttatcctt ttggatttaa
    10561 agaagacttt acaccagaat gtataacaga aaacactttt gggatacatt ggtggggaaa
    10621 aagttgggct aaaaagagaa attatttctt agaaagcaaa cacttaacag gtgtaaataa
    10681 gatatggaag tgttgtaaaa tatttgcaag taatacttta cgaagctaaa agggagaaag
    10741 taaaatgaag actttaaatg atgatagaaa tattatgatt agaaaatatc tttatatatt
    10801 tgttttgttt atcatattac ttagaaagta tatgatatca tttattgacc caaatatgga
    10861 tatagggatg attaaatcag cgttatttta ttcttcaata ggaatactaa tgctactttt
    10921 tttatttgac aagagaaaaa gtataacaga aatggtacta gttggagttt gtgtcttact
    10981 ttatttatta aatagggaag gagctatatt attaatcgtt ttattagctg tatcagctaa
    11041 gcaaatagat gataaattta tagttaaaaa ttatttaata atatcagcat gttttttaat
    11101 ggtagctata ttattattta atctatttcc ttcattgata tttaatcagg aagtccacta
    11161 tagatatata gaaaaaatag atatgcttgt tacaagaatg gattttggac ttggtaatcc
    11221 aaatagtgta ttttatcata tggttactat atatgcagca tatatattct taagatataa
    11281 agattataat aaatgggata gaataatttt atttggttct gcattttttg tttatcaaac
    11341 cacatatagt agaactggat ttttcactat attagcagga ttaatatttg tagaaataat
    11401 aagatggata gatataaaaa aaataaaagg actaccaatg ctcctaaaga cattaccgat
    11461 aatacttact ttatttagtg taattattgg tacagtattt gataaaagca ctttattaaa
    11521 tagattatta gcaagtagac ctaagttctg gcatgtatac ttggctgaaa aggggaattt
    11581 tctaaaacct tttggaaatt catatagtcc tgctataaaa gcaactaatc cattagatag
    11641 ttcttatgta tatataatta gtgtactagg agtagttgct tgtatattat ttatgtattt
    11701 gatgtataaa ggaatagaaa gctttataga aaaagataaa aaagcatatt tagtagcttt
    11761 atttatattt ttactatact cttttgcaga aaatttatta ttagaagctt catttagttt
    11821 tgcagtagta ttactaataa aagaagtgat attaaatgat aaaagggaaa tagatttgtg
    11881 gaagatgaaa agtaggaggt agtaatgtta atatcattaa taatgccaac attaaataga
    11941 tatgatgata tatacttact tatggacagc ttagaaaatc aaacttacaa aaactttgaa
    12001 cttatagtag tagaccaaaa tgataatagc aaagttaaag aaatagttga taaatacatt
    12061 gataagttag atataaagta tataaaaagc tctaaaaaag gattgagtta taacagaaat
    12121 gtaggcatag acaatgctgt agggcaaatt ataggtttcc ctgatgatga ttgtgtctac
    12181 gaaaatgata cattagaaaa agttataaat ttctttaata aaaataaaga ttataaaata
    12241 tacagttgca aaactatgga ttcaaataaa gttgatgcat ttaagaaaat gtatgatgga
    12301 acttgtgata tcacaagttc caacgttttg gatactataa catccataac tttttttatt
    12361 gattttgaag gtaaagacta tacaagattt gatgagaaat tgggtgttgg tggagagttt
    12421 ggtgctggtg aagagataga ttatgtttta aacttattga gtttaggttt taaaggaaaa
    12481 tactttggaa atgatataat ttaccatcct gcaaaaaaac attctaaatc taaagaaaag
    12541 tatcaaaaag attataacta tggaagaggc tttggagcgc tttgcaaaaa ggaaatagtc
    12601 tatagaaaaa attataagtt tgcaaaagtt atggtatcaa aacttgtaag aaatatagga
    12661 ggtcttatat tgagttccaa tagagattat catagtgcca ctataaaagg aagaattaat
    12721 ggatttagac agtacaagtt ataatgagga tggtgtttat ggacaaggtt aaatttttaa
    12781 taaatatgct tttggctttt tttatatatc catttaataa gcataagttt aatggtagag
    12841 atatctggct tataggtgga cattcagggg atatatacaa tgataattca aagttttttt
    12901 atgagtatat gctaaaagaa cataatgatg tagaaactta ttgggtagta aataaagaca
    12961 gtaaagtatt tgataaaatt ccaggcaaaa aattaataag aggaagtgta gaaaactatc
    13021 tgtattatta caattcaaaa gctatagtat tttcacatgc accatcagca gatatagcac
    13081 catacaattt tgctgtacct gttcttaatt attttcataa aaaaacgata aaagtgtttt
    13141 taaatcatgg gactataagt tttaaaaaaa gaaaacctat gaacaaaaag ttcaaaaata
    13201 ttatagataa cctatataaa agctataata tagttacagc aagttctgaa tttgaaagaa
    13261 atgttatggt aaatgattgg ggaatgttag atgactcagt ttatataatt ggaaatgcaa
    13321 gatatgacaa tttaccaaca aatgaagttg cacaaactcg agatatatta tatactccta
    13381 catggagaga ttggataaaa tttagttcag gaaaatttac ggatacagat tattttaaaa
    13441 atataatgaa ttttttaaat gatgacaaat taaataaaat attagatgag aaagatataa
    13501 atgtaaaaat ttatatgcat catcttatgc atgagtttat agatgatata aaagaaaata
    13561 taacaggaaa acgaattgtg tttttagata aaggggtaac tctagcaaat gaaatcagaa
    13621 aatcagctgc aaatataact gattattcaa gtgtagccat agactttttg tatatgaata
    13681 gacctatttt gttttaccaa ttcgatttgg atgaatatat ggaaaaagtt gattcatata
    13741 tagatttaaa aagtgaaatg tttgggtctt tggcttataa taatgatgaa gccgtgaata
    13801 aacttattga tattattgaa aataattttg aggttatgga taaccaaaaa aatgaaagaa
    13861 ataagttttt cagatataat gataataaga actgcaagag gatatatgat tgtgtattaa
    13921 gtaaaattaa ataaatattt tataaatgat gaggaaggta atatgaagaa gaatttagta
    13981 tctataatta ctcccatgta taattctgaa aaatttattg aagcaaccat aaaatcagta
    14041 ttaaaccaaa cttatcaaga atgggaaatg ttaattattg atgattgctc aacagataat
    14101 agtcctaata tagtcaaatc ttatatgcaa caggatagta gaataaaatg tataaagact
    14161 gagactaata agggtgtctc taatgctaga aatttagcac taagtaaggc aacaggacaa
    14221 tttatagctt ttttagatag tgatgaccaa tggaatagta gtaagttaga aaaacaagta
    14281 aattttatgt tagaaaatga ctatgtaatt tcatttactt catatgaact gatggatgaa
    14341 aatgataaaa aattaaacaa agtaataaaa gttccaccta atgtagatta tagaagatta
    14401 ttaaaaggaa atatcttagg atgtcttact gttgtgattg ataagtctaa attggatttt
    14461 gaaataagaa tgagtggtgt aagacatgaa gattatgttt tatggttatc gatattgaaa
    14521 aaagggcata ttgctcatgg aataaatgaa gttctagcat tatatagaaa atctagtaat
    14581 tccctaagtg gtaataaaat aaaagctgct atgtggactt ggaatatata tagaaatata
    14641 gaaaaaatac ctttatacaa agctatatac tactttatta attatggaat aaacggaatc
    14701 aaaaaaagtt agacagagag gaagatttaa ttaatgtata aatataaatt tactgtattt
    14761 actccgacgt ataacagagc tcatttactt gaaaatttgt acaatgattt aaaagctcaa
    14821 acttatgatt tcaatgattt tgaatggttg attgttgatg atggaagtag cgacagtact
    14881 aaagagttag ttgaaaaatt tatatcagaa aataaattaa atataagata tatatacaaa
    14941 gaaaatggag gaaaacatac tgcaataaat ctaggtgtaa aaaatgcaga tggagagcta
    15001 tttttcattg tagatagtga tgatggttta attaaagatt ctcttgaaat tgctaatgat
    15061 gagtgggatt ctttagagaa taaagaagga tttagtggag ttgttggact ttgtgtatat
    15121 ccaagtggag atttgatagg gacagaaatg cctgaagata agaaaatatg tcactttgca
    15181 gacctatatt ttaagtatgg cgttaaggga gataaaagca tagtatttgt aactgatgag
    15241 cttataaaat ttccttttcc agaaagaaaa gaagtgagat ttttaccaga aagtgtagta
    15301 tggaatgaaa tgtctaaata ctataaagtt atatgtgtaa ataaacctat gataataaga
    15361 gattatttgg atgatggttt gactaagaat atattaagta aaaatgcatt aagaggtaga
    15421 gcattagagt ttttatattt aataaatcaa aatacatatc cattaagtag atatccatat
    15481 atgtggataa aaaattacat aaatttagcc agatactcat tgttgtctga tagtcattat
    15541 tttggtgaat taagaaaagt atctgataaa ttgttgtatt tagcattatt cccattagga
    15601 tattacaaat atattggaca aagaaaatta gtatctaagt aaacttgttg gtatagtact
    15661 gctagttgct atataaggag agtaaaaata tgaatgagcc tttagtatcg ataattactc
    15721 ctgtttataa ttcagaagag tttttatcag agacgataaa gtcaatccaa aatcaaactt
    15781 ataaaaattg gcagctttta ttagtggatg attgttctaa ggacaattca agtgaaatta
    15841 taaaaagttt tcgaaaagaa gatgctagaa taaaatatat aaagcttgaa aaaaattctg
    15901 gagctgcagt atctagaaat gttggtatta agaatgcgga aggtcgattt attgcatttg
    15961 tagatagtga tgatttatgg gatagtagaa aattagagat tcagatagaa tatatgttaa
    16021 aagaaaatgt aggtttttct tttacatctt atagatatat gagacaagat gggtcaaaaa
    16081 cgaataaggt tgcaagagct cctaagaaaa ttgactatga aggattactt agaaatacta
    16141 taataggatg ttctacagtg gtcattgata aggagattgt aggagagttc agcatgcctt
    16201 tggtaagaag aggacaagat actgcaacct ggttacagtt acttaaaaag gaaaaatatg
    16261 catatgggat tcaagaagat ttagtgaatt acagattagt tggaaattct atatcaagta
    16321 acaagataaa agcattaaaa cgaacttgga atacttatag aaatgttgaa aatttaagtt
    16381 taccaaaaag tctatatgta ttttgtttct atgtttttaa tgccattaaa aaaagagtat
    16441 aagttttata tacttggagg taaaaaaatg aaaatagcta tagctgggac gggatatgta
    16501 ggtttggtta caggtgtttg tctagcagag gtaggcaatg aaaatgtagt ctgtgttgat
    16561 gtagatgaac aaaaagttaa atcaatgaaa cttggaatag cacctatata tgaagaaggc
    16621 ctagaagaac ttatggttaa aaattacaac agaggaagaa tagattacac tacagactat
    16681 aaaaaagctt atgaagatgt agatgtaata ttaatagctg taggtacacc tgagagaagt
    16741 gatggttcag ccaacctaga ttatataaag gcagttgcaa agcaaatagc tgaaactgtg
    16801 acaaaagata ctctagtagt aataaaatct acagttccaa ttggtacaaa tgaagagata
    16861 gaagattata taaatagaaa cctaaaaaat gatgtaaaag tagaacttgc atctaatcca
    16921 gagtttttat cacaaggaac agcagtaaaa gatactctac atgcttcaag aatcgttata
    16981 ggtgtagaaa gtgaatgggc tagagaaata ttagaggaaa tctataagcc ttttaatcaa
    17041 cctataatag ttacaaatag aaatagtgct gagatgataa aatacgcatc aaataacttc
    17101 ttagctctta aaatatcatt tatgaatgat attgcaaatc tttgtgaaat agcaggagct
    17161 aacatagaag atgtagcttt aggaatgagt tatgatgata gaataggaag taagttttta
    17221 aaggcgggaa taggatatgg tggttcttgc tttccaaaag acacaaaagc tcttcactgg
    17281 ttatctgaac ataatggtta tgaattaaaa acagtaaaag ctgcaataga agttaatgaa
    17341 agtcaaaaac ttaaattagt tagaaaggca tctaagttag tagagagctt tcaagatatg
    17401 aaggttgctg ttttaggttt gacttttaag ccagacactg atgatataag agaagcacca
    17461 tctataccaa atataaaata tttgctcgaa agaggggcaa gagttactgt atacgaccca
    17521 attggtgtaa ataatactaa gaaaatattt ggtgactcta tactttatgc tgattctgta
    17581 gatgatgcga tagaagatgc agagatatgt tttataatga cagaatggaa agatgtatta
    17641 aattatgata tacataagta taaggaaaag atgaaaaatc ctttagtcct tgatggaaga
    17701 aattgttata aaattaaaga tatggaagag ttaggaattg agtattattc gataggaagg
    17761 taaatattat gaagactgtt tgttatttag ctgatgggtc aaatcctcat actttaaaat
    17821 ggtgtagttt ttttaaaaat aaaggatatg acattcatgt aatctcttta aatggaggtc
    17881 acatggaagg aataaaaatt tataattttg gttctaatgt agaagaacta aaaaatgaaa
    17941 atatttctaa aaaaacggga tacttaggtt caataaagca gataaagaag ctagtaaatg
    18001 aaataaagcc agatatattg catgcacagt atgcaagtag ttatggattt ataggaagtc
    18061 tacttgggta tcatccatat attatttctg tttggggtac tgatatttat gatttcccta
    18121 ataatggttt tatacaaaaa caaattataa aacataactt tagaaaagca gactatatct
    18181 tttcaaatag tagagatatg gctaaagagg ctaataaata tacagctaaa catgtagatg
    18241 taaccttttt tggagtagat atggataggt ttaagcctat ggaagtagaa aaagaagacg
    18301 cttttgtaat aggaattata aagagtttag aaaaaaaata tggaatagaa tatttaatac
    18361 aagcatttaa gatgcttaaa gatgaatata aagataagaa aataattctt aaaataggtg
    18421 gctctggaag tcagatggac aacctaataa atttagctaa agaattgggt atagaaaatg
    18481 atgttcagtt tttaggaaga atatctccag aaaatgtaag caagactttt aattcttttg
    18541 atgtaactgt atttccttct ttaagagagg gatttggagt ggcagctata gaatcagaag
    18601 catgtgaagt acctgttata gttacaaatg taggaggaca tccagaatct gtatgggaaa
    18661 atgaaactgg cttaattgta gaaccaaaac aaccagaaga aataaaaaat gctataataa
    18721 aactaatgga aaatgatgaa cttagactta atatgggtaa gaaagggcgt caatttgtta
    18781 gagaaaatta tgaggttaat ttaaacttta atgatataga aaaaatttat gattctatat
    18841 ttgataaata taaaaaataa aatgaaaaaa tacagcaaaa gatagatgtt gttggctatg
    18901 cttaggtgcg tagcttttgc tgtttaaagg agggcttcta gttatgcgag aaagtataga
    18961 tttagagaaa gaaagctttt ttaataggct ttttaaaaaa tataaattta gacatttaac
    19021 actattaatt ctagatattt gtagcgtact agtagcgttt cgaatgtctt taagcttgac
    19081 aggtaattta aatgcattta ccactaatga tataataatt tcagcgtgta tatatatagt
    19141 acttcatata gtatcattta gattgtttaa gtgctacaac acattatgga gatatgcagg
    19201 agaagaagaa attatatcta tttttgtggc aactttagct tatttaattc cgatttatat
    19261 aataaataaa ttattagggt ttgattatcc tataatgttt tatgtattaa atacaatatt
    19321 tattataatg tttacaagtg gcgcaagaat agcctataga gctataagaa tagtcatgaa
    19381 caagacatat tctagaggaa aggtttcaaa tatccttata attggtgcag gagatgcagg
    19441 agaaatggtt atacaggaac taaaaagaaa tccagaactt aaaaaagtag cagtggctat
    19501 aattgatgat gataaaaata aaattggaag aataatccac aatgtgaaaa ttgtaggaac
    19561 aacttcagat ataaaagatg tggtagaaaa gtacaatgta gatgagataa tcttttcaat
    19621 agcaaacata gagaaacgta gaaaaaaaga gattattgat atatgtaaaa acactaactg
    19681 taaaataaag acaataccag gaatttacga aattatagat ggaaaagttg atataaaaca
    19741 gattagagaa gtagagatag aagacttgtt gggtagagag cctataaaaa caaatttaag
    19801 agagataagt aattacattg agggaaaagt aatcctaata actggaggag gaggctcaat
    19861 tggttcagag ctttgcagac agattgcagg atttaatcct aaagagctta ttatagttga
    19921 taattatgaa aataatgctt actcaataca acaagaattg cttagaaaat ataaaaataa
    19981 attagattta aaaacagtaa tagcatcaat aagagaagaa aaaagaatgg atgaaatatt
    20041 taataaatat aaaccagaag tggtatttca tgcagcagca cataaacatg ttcctcttat
    20101 ggaatcgagc cctggcgaag ctataaagaa taatatattt ggaactttaa acatagctgg
    20161 cttgtcttca aaatatagag ctaagaaatt tgtccttata tctacagata aggctgtaaa
    20221 ccctactaac ataatgggag ctactaaaag agctgctgaa atgattatac agactatgaa
    20281 tgctgaaagc cagactgaat ttgttgctgt tagatttgga aatgtgcttg gtagtaatgg
    20341 tagtgtaatt ccacttttta agaagcaaat tgaagatggc ggaccagtga cagttactca
    20401 tccagatatt attagatatt ttatgacaat accagaagca gtaggcttag ttatacaagc
    20461 tggggctatg gctaaaggtg gagaaatatt tgtacttgat atgggagaac ctgtaagaat
    20521 attggattta gcaaaaaact taattaaatt cagtggattt gagccagatg ttgatataaa
    20581 aattgaattt tctggtctta gaccaggaga aaagttgtat gaagaactac ttatgtcaga
    20641 agaaggtctg ttggatacag agcataaaaa gatttttatt ggtagaccaa tagatgttga
    20701 tagagaaaaa ataacaaaat acttaaaact tttaagagaa attactaaca atgaagaggt
    20761 tgaaaaaata gatggtatta tgagggaatt agtgccaact tatattaaac cagaagatgc
    20821 taatatcaaa gaaattgcaa caactagaga aaagtagaat atatttctaa tttgtaacca
    20881 gggggagcaa aaagaaacaa atatatacta aaaagaaaca aaagattaca aaaagattac
    20941 aaaaagatta caaaaaaggt tgcaatttat tttgatgtaa gatagaatgt taattaggaa
    21001 ttggaaacga aggaacaaaa tgttaaattt tcgaaaggat taggtatttg agattatgat
    21061 gaatattaaa aataaaaaac atatattgaa aaaatttata gctatggtgt taatagcagg
    21121 agttgtcaca gtagaagcag gagcaataac ggctagtgca gcagagccaa ctaattcacc
    21181 tatgagtgca acagtagacc agtgtgattt tttaaatgta agaagtggag ctagtgcaaa
    21241 tgatgcagta gtaggaaaga taaacacagg agacaaagtt gaagttttag aattacattc
    21301 aaatggatgg attaaaataa aaagtgttga caatgttaca ggatgggtaa atggagatta
    21361 tttaactatt caaggtggaa atgtagatgc aaaggtacaa aatgttttaa acttagcatt
    21421 taagcaacaa ggtaagccat ataaatgggg agcaactgga ccaaattctt ttgattgttc
    21481 tgggttcact tcttatgtct ataaaaatgg agcaggagtt aatttaccaa gagtatcaag
    21541 atcacaagca acagtaggaa agaaagtatc aagagcagaa ttaaaaccag gagatttagt
    21601 tttctttggt tcaggtggtt caataaatca cgttggattg tatgtaggag attctaaatt
    21661 catacattca ccacaaacag gagatgtagt aaaagttact agcatggctc caggaactaa
    21721 ttatgcaaga agacttataa ctgctacacg tgttttacaa taataataga tattgattta
    21781 cataggattg aatattaaca ttaaatatat aattacattt aatgttttac atagagattt
    21841 aagagtttag taatattaaa atagtgatga acgttataaa aacagcaaag aagataaatt
    21901 tctttgctgt tttttttata ataaattatt tcatattata atcaaatatc aaatataaat
    21961 tttaactata ttattcaata tttgacagat aatatgaatt ttagatatac ttaataagaa
    22021 gtatattgta gaaaaaataa atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta
    22081 tattagtatt atcattgata atgacactta ctatgtgtag tgtaagttca tttgctgatt
    22141 catcaaatga taaggaaatg agagctgctt ggatatctac agtttataat ttagactggc
    22201 ctaagactaa gaataatgaa gccaagcaaa aaaaggaata cacagattta ttggacaaat
    22261 taaaaagtgt aggaataaat acagcagtgg ttcaagtaag accaaaatca gatgctttat
    22321 ataaatcaaa tataaaccca tggtctgaat atcttaccgg tacacaaggt aaagaccctg
    22381 gatatgaccc attaccattt ttaatagaag aagcacataa aagaggaatg gaatttcatg
    22441 catggtttaa tccatataga ataactatgg cagatgagag catagataaa ttgccagcaa
    22501 accatccagc aaagaaaaat ccaagctggg tagttaaaca tggaaataag tattactacg
    22561 acccaggttt accagaagtt agaaagtaca tagtggatag tatagcagaa gtagttcaaa
    22621 attacgatat agatggagtt cattttgatg attacttcta tccaggagta agtttcaatg
    22681 atactgcaac ataccaaaaa tatggaaaag gacaaaataa ggatgattgg agaagagaaa
    22741 atgtaaatac tctacttaga gatgtaaaag cgtctataaa gagtataaag cctaatgttg
    22801 tatttggtgt aagcccagca ggtatatgga gaaataagag tagtgaccca acaggttcag
    22861 atacatcagg taatgaaagt tatgtaggta catatgcaga tacaagagca tggataaaac
    22921 aaggattgat tgactatgta gttccacaac tttactggcc aattggtctt aaagcagcag
    22981 attattctaa attagtggca tggtgggcta atgaagtaaa aggaacaaat gtagacttat
    23041 acataggaca aggtatatat aagcaaggtc aatcgagtta tggtggacaa aatatagcaa
    23101 aagaaatagt acaacaagta acattaaata gaaagtatag tgaaataaaa ggtagtatgt
    23161 atttctcagc taaagatata gcaaatagta cttctataca aaaggattta aagagtttat
    23221 attctagtag tgaagaacca gttactccac catctaatgt taaagtggag aaattaagag
    23281 gcgacgaaag atatgacaca gcagtagcaa taagtaaaaa aggttgggct acaaattcag
    23341 atacagtagt attagtaaat gggtactcta tagttgatgg tataacatca acaccacttg
    23401 ctacatcaaa tgatgctcct atactattgg taaataagga taatatacct acatccacta
    23461 agaatgagtt aaaaagactt aatccaagta aagttatttt aattggagga aataactcta
    23521 ttggagataa agttgagagt gagataaaag atacattgtc aaatgtatca ataaatagag
    23581 ttggtggttc agatagatat agtacatctt taatgatagc aaaagaatta gtaaaaacta
    23641 atccagtaga aaaactatat ataacaagtg gtacaggtga agcagattct ctttctatag
    23701 cttcaaaagc aggagaagaa aagcaaccaa tagtattagt atcaaaagat aatgtaagtg
    23761 atgaagttta caattggata tcagatttga aagtaaaaga tgcttatttt ataggtggta
    23821 atctaagtat atctgattca gtaataaata agctggataa ggtcattaca aatgatgtat
    23881 ctaaaaatag aatagctgga gaaaatagag aagaaacaaa tggaaaagta atacaaaaat
    23941 tctatccaaa tgctgaatat tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg
    24001 cattaacatc aggtccttta gcagctaaat taaaatcacc agtagttatg cttggaaata
    24061 gtgtaacatc tgctcagaaa actgctttag agcctaagaa aactactcta gtatacgaag
    24121 ctggagatgg tataaatcaa aacacattaa acactttctt aaacttagtt aagtaataaa
    24181 aaagttaatt taaaatacag agtattttat aaatgtagat taaaatgaaa attatcatga
    24241 taaattagaa aataaaaaag aactatatgc attttgtaat caagtgtaca cagcaacttg
    24301 aaaataatta tgcgatatag ttctttttta gtaattaatc ttatactttt taataaactt
    24361 tatgttgaat tttttattgt ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt
    24421 ctaaagtatc tgggtcaaat ctaagaaccc atccagcttt tccatatata ccacctgtac
    24481 tatgaatttc atcatcaata ggaaattcaa attgcttaat atttaagtcg cccattttta
    24541 aaacttgagc tcctaaagaa agtattgcat taggcttcat gttagtttta acatatggaa
    24601 gaactgcatc taataaacct ggatatttag taacaggtaa agtttccgtt ttcttgatta
    24661 tagcttgtat aatctgtctc tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga
    24721 tacgtgcaaa agatagtgcc tgatatccat ttagagtctg ctttccagag tttctaatgt
    24781 attgtatgct acctttatca tcacttttat tccatttata agtttcagga ataaatttat
    24841 ttagttctcg tatttctcct ttttcaacag taacctcaac gccaccaata gcatcaatta
    24901 tatacataaa tgattcgaaa ttaacacaag cataattttg aatatcaata ttaaaattct
    24961 cttcaattgt ttgtattaat aaatcagctt gtccataagc ataagcatga gtaagttttt
    25021 gtttaccatg accagggatg tctacatagc tatcacgagc taatgatgta agtttgatat
    25081 cattgtgttt gttatcaata gtaagtatca tcatagcatc tgaccttgaa gaatcttcat
    25141 ttggtctagc atctgttccc ataagtagta tgttaattat cccatcttca tttttatggt
    25201 cattgttatc caataaatca ctacttatgc tcgagtcatg aatagcagat aatttataat
    25261 aaaaatatcc atagacactt atagggaata ttactaccaa gaaagccagt agtataacaa
    25321 atttctttaa ttttgacaaa agtacccctt ctttcttctt tttcctgtat attttttaat
    25381 agcatacact taattatatt aaagtattga gatatattca atacttgttt cagttacaaa
    25441 aaaaagacaa tgatataatt tataagaaaa tttatcgacc tatatatata gttaaaagta
    25501 tatataatat attttttaaa agtaatttat attttaaaat aaaaacacac cccataaata
    25561 caaagtaatt tgcatttaag aggtatgtat ttatcatcaa attattggtt tgttttggaa
    25621 tttctaatct tcaaccataa tatctttaaa tatgaaatca tgcattgcat ctagttcata
    25681 ttcctcaaaa ggtattacat agcctgcatt acctattttt ctaccatttt cagtagaaag
    25741 aggaaactcc atagatttca aatttaaatt tcctatactt aaaagttctt ttcctaaaga
    25801 tattatttca ttaggattca tattagtttt tacatacgga agtattgtgt taactagatt
    25861 aggatattta gtgactggta aatccttaac accatttatt aaactctgta taacacttct
    25921 ttgtcttcta tctctttcat ctgtactatc attttttctt atacgagaaa atgcaagtgt
    25981 ctgatatcca tttaattttt gctcaccaga atttcttata tatttaagag aacctttatt
    26041 gtcattttta ttccatttat aagtttcagg aataaattta tttaattctc ttatttcact
    26101 cttatcaaca gtaacagtaa ctccacctaa agcatcaact atatccataa aagagaaaaa
    26161 gtcaactacg gcgtagtttt gtatatcaag ttggaagttt tcttctatag tttctattaa
    26221 taagttagct tgtccatata cgtaggcatg tgttaatttt tgttctccac gtcctggtat
    26281 attaacataa gtatctctat ttaatgaagt tagcttaaga cttttatttt tattatcaat
    26341 agtaagtatc atcatggcat cagaacgaga aacttcttct cctggtcttg catctgtacc
    26401 taacaataat atgtttgtga tattttcttc gtttttatag tcattactac taagcgcctc
    26461 tgtatttata ctatcatctt gtatagtttt taatttagta aaaacatatc catatatact
    26521 aacaggaaat gctataacta aaagggctag aaatataacg aactttttga gtcctgacaa
    26581 taatatcccc tactttctaa attttttaat tacacatagt taattatatt aaaaatttgt
    26641 tacataagca ataaaaaaca caataaatta gcataagttt gtcataatat aattattttt
    26701 atagcatttt atagaagaaa gtgtgtagtt attattgatt ttattggaat ataattgtat
    26761 gaagacttaa atttttataa actgatgtgt atattgaaaa aaatattttc ctgaatgtag
    26821 ttatagcatc ttatgaaagg tgcaaattgt aatttaaaat ttttagtgta taataagaat
    26881 tgaaaattca aaccgataaa aattaataaa aaataattat aaattaataa tttgggggag
    26941 gaaatgtatg ataaaattaa tagcaacaga tttagatgga actttgttag atgaaaagag
    27001 cgaaataaat ccagagtttt ataaagtatt taaaaaatta agagagagag ggataatgtt
    27061 ttctgctgct agtggcaggc agtatcaaaa tcttataaaa aaatttgaag atataaaaga
    27121 tgatatgatg tttatatcag aaaatggaac actagtagta tataaaggaa aagaaatatt
    27181 atcaaatcct ttaaataaag aattagtaaa tgaaatcata gagacaacaa gaagtataaa
    27241 agggaaaaaa attgtaatga gtgggaaaaa atacgcttat atagaaagca aagatgaagc
    27301 gtttatacaa gaggtcagta cttattatgc aaagtttaaa attgtagaag atttgacgaa
    27361 agtagaagga gacatattga agatagctgt atttgacttc aaaggtgcag aacataataa
    27421 taatatctac tttgaaaagt tttctgatag agctcaagta tgtatttctg gagtggagtg
    27481 gcttgattta actgcaaaag gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat
    27541 gttagatata aaatatgaag aaactatggt atttggtgac cagttaaatg atgtggaaat
    27601 gatgaaaagt gcctatcata gttatgccat ggaaaatgca aatgaacatt tgaaacaaat
    27661 tgctagattt agagcaaaaa gaaatactga aaatggcgtt gtagataaga taaaagaggt
    27721 tataaaaatt ggatagtcat atgtatagat gaaaaagatt attttgaaga aatcaaaaaa
    27781 atatcaatgt aattttgata aataagttta tttatgcgaa aattacattg atatttaata
    27841 aacatcaata atagatattt atttttttat gatattcagt attttgtttt ctatttgagt
    27901 tgcattttca gcagaaatta aataaacata tctacctgcc ttctcaatta tagtattatt
    27961 tgctatttca gaattgattt tttctccatg tccttctcca aaaggtgctt gtatcatatc
    28021 ttttttataa ttttctagag ttttatagat tttatctacc tcgtcagttt ttataacgat
    28081 aatatcttct agagataatt tttcagaaga attaattaca aaaccttgaa ttatgtcttc
    28141 ctctacatca ttaaaatagt taaaatcctt tgcatcaaag atttttgatt cctttataag
    28201 taaatcagaa gattttaatg ctttttttat ttttgatgta gaaacgtttt tgtaatcacc
    28261 acttgaagaa caactaacca ttcctaatga taagattatc gaaaaaaaca atattaaaat
    28321 ttttttcatg ataaacctcc aagtttttta aactctgtct taaattagtt tactacataa
    28381 ttatataaaa ataaatgtat ttaatgttac agttttgatt aataatgtaa tattttgata
    28441 ataataccta ttgagaggtg attagaaatg agaataccaa aacatgtagg aattataccg
    28501 gatggaaata gaaggtgggc aagtcaaaat ggtatgacaa aagataaagg atatgaaagt
    28561 ggaatagacc ctggactaga gtcttataga ttatgtagag atttaggctg tgaagaggtg
    28621 actttttatg gatttacaac tgataataca agacgtccat cagtgcagac aaaagctttt
    28681 acaaaagcat gtattgatgc tgcaaatata ttaatagatg aaggtgctgc tttattagtt
    28741 gtaggaaata caaaatctcc aatgtttcca gaagaattat taccatatac taatagaatt
    28801 aaagccaaag aaggtcaaat aaaagcaaat cttctggtaa attatggttg gtattgggac
    28861 ttaaataata tatcaggagt agaaaatgta aataaaaata atatacagga ttacatacag
    28921 tcatttgatg tatccagact agacttgata atcagatggg gtggaagaag gagattaagt
    28981 ggtttccttc ctgtacaatc aatttatgca gatttttatg ttatagataa ttattggcca
    29041 gattttaaga gtgacgatat aaaggacgca tttagttggt atgatacaca agatgtcact
    29101 ttaggtggat aattaaaaat attctgattt aaggttgtag agtgttttaa attattgaaa
    29161 aaaaaacttc ttgatggtaa aataacacta ataatatgta aaagtgtaaa aatttatacc
    29221 aagaagggtg aagaaatgtc aaaaggcaat aataacaata attcaagaaa caaatctaaa
    29281 aagaccagtc atctgaatag aaaaaagcga aaattaaata agaaaaagtt agcagtgttg
    29341 atttgcttta cagttttatt tttatttatt gcatttaagg ctactcaagg tgtagtagct
    29401 ttggtaaaaa gtatggataa aagtaataaa actaatcaac aacaaaatgt taactcagaa
    29461 caatttgacc ttggtaatga agaggaaaat aaaaagaaaa aatatactgt atttatagac
    29521 ccaggtcatg gaggcaatga taaaggaact gaaagcaaga ccagtaatag atatgaaaaa
    29581 gacctaaatc tacaaattgc aaaaaaatta gcaaataaat tatctaaaca aaaggatatt
    29641 caagtagtag tatccagaac tgatgataca tatatatcat taaaggatag agctatctta
    29701 gcaaataata gttctgctga tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt
    29761 aatacagcaa caggtataga aacttggtat aggaataaag ctacagatgg ttcaaaagaa
    29821 cttgcacaga cagtacaaag tactatagta tcctatgtta aagttagaga taggggaata
    29881 gttgaaaata actttgaagt acttagagaa tcaaatatgc ctgctatatt aatagagtgt
    29941 ggttttttaa caacaccttc agaggaacaa aaaataataa atgaaaaata tcaagaccaa
    30001 cttgcggaag gaattgttca aggtgtactt tcatacctag attctaaagg gaataagtaa
    30061 gttaacttta ctttaatgtg aggataaatt taaaagttta actgtgtaaa ttgtattaac
    30121 tttatttcgt aatgttgcaa acattgtttg aatttagaaa ctatgaaatt agaaattatt
    30181 ttatctatat ctaatttcat agtttttttt gcaaaaaatt tatagttata aaattttaaa
    30241 aaataaattt agtataatgt aatgtagtta tttatatgtg attttaactt gcattgattt
    30301 gctatcaatt gtgctttata attagtatat ataaagttta actgtaagat aatttaaaaa
    30361 ataggggaat ttatatgaat aaaaatagca tgacaagaat ttacagttta aataaaataa
    30421 tttttattat aattggaatt ttaggaatag ttttactcac aagacatatt gaggtagata
    30481 ttaaagtttt aattttaatt ttattaacct tgtttagtat aaatgtattt atttcatatc
    30541 ttaaaattaa gttgtatgag gataaaatta atttaggatt gataaataat tcagataagt
    30601 ttataaatat tactaaagat gagaacttcc taaaacatgt tcaaaattat attatcagta
    30661 atgaaaaaga aaactgtgta atggcttgtt ttgatttatg tagactcaaa cttataaatg
    30721 atatatatgg ttatgagcta ggggatgaag tgttaaataa tattttaagt aacttaaaaa
    30781 attattttgg aaaagaagct atttatggaa agttaaaaag tgatgttttt gtattaataa
    30841 taaagcttga aaatagggaa cagaagattc cttatttagt aaatcttatt aagaataaaa
    30901 ttgtgatact aagtcagatt gacagtttta aaatggatat aaatattgag gcttctattg
    30961 gaatttataa atttaacaat aatgaaattg atataaaaaa agctatagat aatgctgata
    31021 tggcaagact taaatcaaaa ggactaaagc acatagagta tgtagaattt gataatgcta
    31081 tggaagaaga aatacaatca attatgaaaa tagagagaga tttattcttg gctattaaaa
    31141 ataaagagtt tgtaattcac tatcaaccta aagttgattc aagtacaggt aacattatag
    31201 gttcagaggc attgataaga tggttgcacc catcattagg catggttgga ccaaataagt
    31261 ttatacctat agctgaaaaa aatggtctga taaacaatat tggtagatgg ctaattcaag
    31321 aagtttttat taccattaac aagtggattt cagaaggtat aaatgtctta ccagtctcaa
    31381 taaatctttc tagagtagaa ctatataaaa atgatttagt tgattttttt aaactgatgt
    31441 ttaatacata taatattcca aaagaactta tagaattaga aattacagaa acgacagcac
    31501 taagagatgt aaaatttata agtgaaaggc tttatgagat taaatcttta ggtatgaata
    31561 tatcattaga tgattttgga gtaggtaatt caaattttat caaccttaag gggataccac
    31621 tagatattat aaaaattgat aggtcactta tattggatat agttacaaat acaaaaacaa
    31681 agtttatggt gaaagcaatt gttaaccttt cacatgattt aaacgtaact gttatatgtg
    31741 aaggggtaga ggatatgcat caggtcaaag tcttaagtga actgggatgt aatttcatac
    31801 aaggttatgt attttttaaa cctttggatg agatgaatta taaaaaactt cttactgacg
    31861 gaagttatat aaatctgaaa gatactcttt tagataaatg catgacagtt gaggaggagt
    31921 aaggatgatt tcagaagatg tagattattc aataagaatc ataagagcta tatttaataa
    31981 tggagaagat aaaccaatag atgctaaaat gatattaaaa agtgaagata taccaatact
    32041 aacactatac agactgctta gaaagctttg tgcaaacaat attcttactt ttaacaaaga
    32101 agatggcaag acatacatgt taaatgtgtc attggataca ataagtctaa gaactattgt
    32161 agaagtaatt gatggaaaaa tatatataaa taaatgtacg agatatgtat ctaattgcag
    32221 taattgctta aaaggttgta aagtaaatcg tgaattgcta gaaatagaaa aagaaattta
    32281 taaactttta tcgagaaaat ctataagaca aatactagaa taaaaaattt tcagctatga
    32341 taataattgg aggttttcgg ttatggatga tatatctcaa gataattttc tactgtctaa
    32401 agagtatgag aatagcttag atgtagatac taaaaaagca agtggaatat attatactcc
    32461 taaaataatt gtagattata ttgtaaaaaa aactttaaaa aatcacgata taattaaaaa
    32521 tccatatcca cgaatacttg atatttcctg tgggtgtgga aattttcttt tagaagtata
    32581 tgatatttta tatgacttat ttgaggaaaa tatatatgaa ttgaaaaaga agtatgatga
    32641 aaattattgg actgttgata acatacaccg tcatatatta aactattgta tatatggtgc
    32701 tgatattgat gaaaaagcta taagtatatt aaaagatagc ttaacaaata aaaaggtagt
    32761 aaatgattta gatgaatctg atataaagat taatctattt tgttgtgata gtcttaaaaa
    32821 gaaatggcga tataagtttg attacatagt gggtaatcca ccctatattg gtcataaaaa
    32881 acttgaaaag aaatataaaa aatttctcct agaaaaatat agtgaagttt ataaggataa
    32941 agctgactta tatttttgtt tttataaaaa gattatagat attttaaagc aaggagggat
    33001 tggcagtgtt ataactccaa gatatttttt agaaagtcta tcaggtaaag atttaagaga
    33061 atatattaaa tcaaatgtca atgttcaaga aatagtggat tttttaggtg caaatatatt
    33121 taaaaatata ggggtatcta gttgtattct aacttttgat aagaaaaaaa caaaagagac
    33181 atatatagat gtatttaaaa tcaaaaatga ggatatatgt ataaataaat ttgaaacatt
    33241 ggaagaactt ctaaagagta gcaaatttga acattttaat ataaatcaga gattgctatc
    33301 tgacgaatgg atacttgtaa ataaagatga tgaaactttt tataataaga tacaagaaaa
    33361 atgtaaatat agcttggaag atatagcaat aagttttcaa ggaataatta cagggtgtga
    33421 taaagcgttt attttaagta aagatgatgt aaagttgaac cttgtagatg ataaattttt
    33481 aaaatgttgg ataaaaagta agaatataaa taaatatata gtagataaaa gtgaatatag
    33541 gctaatatac tcaaatgata tagataatga gaatacaaat aaaaggatac tagatgaaat
    33601 tatagggcta tataaaacaa aattagaaaa cagaagagaa tgtaaaagtg gaataaggaa
    33661 atggtatgaa cttcaatggg gtagagaaaa gcttttcttt gaaagaaaaa agataatgta
    33721 tccttataaa tcaaatgaaa atagatttgc tatagattat gataataatt tttcaagtgc
    33781 agatgtatat tcttttttta taaaagaaga gtatttagat aaattttcat atgaatatct
    33841 agttggaatt ttaaattcca gtgtttatga taaatacttt aaaataactg ctaaaaaaat
    33901 gagtaaaaat atatatgatt actatcctaa taaggttatg aagataagga tttttagaga
    33961 taataattat gaagagatag agaatttatc aaagcaaata atatcaattt tattaaataa
    34021 gtctatagat aaaggaaaag tagaaaaatt gcagataaaa atggataact tgataatgga
    34081 ttctttaggt atataagcag ttgtaagtat taaaaaatta taatctttta attgtttatt
    34141 taaatttaga aataaaaagt tagccatata aaaaatatta aaaatatata cttttcaata
    34201 tttttttgat aaaataagaa tgaatttgtg caattttatt tttctccaat aactaaaaat
    34261 agttttttga attaatattt gcttaagaat aaaaatcaga aacgtttttg atatagtagg
    34321 tgataatatg aaaggattag ttttagaagg tggaggaaca aaaggagcct accaaatagg
    34381 tgcatataaa gctttaagag agcttggtat agagtttcaa ggagtaactg gcacatcaat
    34441 tggtgcttta aatggagcat atatagttca aaatgatatt gaagtaatgg aagatatttg
    34501 gttaaattat gactatactc attttatgaa tattgataga gaaacctatg agaggtttaa
    34561 aaatgtagat ttcactacta aaaatctcaa tgcagtgttt gagcttataa ataaagctag
    34621 aaaaaatgaa ggtatagata taagcccatt aagacaacta atggagacaa cattaaatga
    34681 agacataata aggaaatcaa aaaaagactt tggacttgtt acggtctggt gggataaaaa
    34741 aattaatcca tatccattgt atatcgaaga tatacctaaa ggaagattga ttgattattt
    34801 aattgctagt tccagtttgc ctatttttca aacgaacatg atggatgata agttgtatct
    34861 tgatggaatg ttttgtgata acatgccaat aggactcttg gaagacaaag gttatgaaga
    34921 tgttgttgta attaggttga ttgatgattt tattgggaaa atgaatctaa atcgacatca
    34981 aaatataaat ataaaaacta taataccatc agaatatcta ggaggttctc ttaataaaga
    35041 tagagataat gtagaaaaaa acatccgact aggttactta gatactatga aagcatatga
    35101 aagatgcact ggaattaagt attattttga tgtagagtat aaatataatg aagaatattg
    35161 ttttgataaa tttagaagta tgagcaatga aacaatacaa tatatctgta atttattgaa
    35221 tataaaaaga gatgcttcac ttagaaccgt tatggaaagt gtaataccaa agcttggtga
    35281 ggtgcttgga ttgccaaagg atttttcata taaagatttg ttttactgta tatatgaaaa
    35341 gaaacttgaa gaaaataata taaacaggat aaaattatat gattttaaca aggttataga
    35401 tgttgtaaat acaaatattg attctaatag aaatttagct tctaattttg aagttagacc
    35461 taaaattagt attaaaaaga acaaaaacac aaaattattg acaaattgta ttataaaaga
    35521 cataaaaaat caaagttaaa taaaaaacaa aaaaaaattt gtaattatac tcgaaaaaag
    35581 tgtatattag tagtataata tttttgtagc actagtggga acaaaaaatg accataggac
    35641 aaaaaagtac cacttagtac cattaaagta aaaaacagga aaacaatttt aaaaaatata
    35701 aaatgtaaag tttataggag gatttaaaaa aatggaaaaa gtagttagta tcaaaaatgc
    35761 aagtggatta catgctagac cagcaggaat gtttgttaag aaggcagctg aatttaaatc
    35821 aacagtagag gttgtagcaa aagacaaaac tgtaaatgca aaatcaataa tgggaataat
    35881 gagtttaggt ttagctcaag gagaagaatt aaagttagtt gtaaatggag aagatgaaga
    35941 agtagcttta gctgcaatgg ttgaattagt tgaaagtgga tttggagaat agatataata
    36001 attttttaaa aatttgatat ttagaatcta atattactta aagtaaagta acagagaagt
    36061 attaaacata tacagaccaa catttgtaga tatttaattt ctttgttact ttcatgttta
    36121 tttaatcaga agattaagac tattgttaat tgggtataaa aatataaata ttttagaaaa
    36181 tgaaataaga tatttttaat cataaattca gagtaaaaat acagtaacaa atagtttata
    36241 aaattttata aaaaattata agtaaataaa actataaaaa tgtaaattat ttatataaat
    36301 ttataaagtt tatgtgctag atgatatttt ttaggaggta gggttatggc ttacaaagga
    36361 ataggtgctt ctcctggtgt tgctttaggg aaagcgttag tagttgaaca tagtgaatta
    36421 gtaattgaaa aaaaatctat agataatgtt gaagctgaaa ttgctaaatt agaagatgca
    36481 gttgcagttt ctaaagaaga attagtaaaa gttaaggaaa aggcttctga agaattagga
    36541 gcagaggaag cagaaatatt tgaagcacat ttattagttt tagaagaccc agagttaatt
    36601 ggttctgcaa tagataaaat taaaactgaa agtgtaaatg cagagtatgc tttaaatgaa
    36661 ataaaagaga tgtttgttag catgtttgag tctatggaca atgagtacat gaaagaaaga
    36721 gcggcagata taaaagatgt tacaaataga atacttagac atatattagg aattaaagtt
    36781 gttgatttat ctgctttaag cgaagaagtt gtattaatag cacatgattt aactccatca
    36841 gacacagcaa ctatgaataa aaaaatggtt ttaggatttt taactgatat aggtggaaga
    36901 acttctcata ctgctatcat gtctagaact ttagaaatag ctgcaatcgt tggattaaat
    36961 gatataactt caaaagttaa ggatggagat tttgtggttt tcaatggaga cacaggtgaa
    37021 gtaatcgtga atcctgatga agagactata aataaatata ctgaattaaa agctaagtat
    37081 gaagatgaga gaaaagcatt acagctatta aaaggaaaac catctgtaac tttagacgga
    37141 aaacatgtgg aattagctgg taacatagga acacctaacg atatagaagg tctaataaag
    37201 aatgatgctg aaggtgttgg tctttataga acagaatttt tatacatgga tagagattct
    37261 ttcccaacag aagaaataca atatgaagca tataaagctg tattagaagg aatggatgga
    37321 aagcctatag ttataagaac attggatata ggtggagata aagaattaag ttatttaagt
    37381 atggaacctg aaatgaatcc attcttaggt tacagagcaa taagactttg cctagataga
    37441 aaagatatat ttaagactca attgagagct ttatatagag ctagtgttca tggaagatta
    37501 agaatcatgt tcccaatgat ttcatcttta gaagagttgt tacaagctaa agaagttgta
    37561 aaagaagttt tagcagaact tgattctgaa ggtgtggctt atgctaaaga tgtagaaatt
    37621 ggtatgatga tagaagttcc atctgctgct gtgatatctg atgtattggc taaacacgta
    37681 gatttcttct ctataggaac taatgattta attcaataca cttgtgcagt tgatagaatg
    37741 aatcaaaaga taagctatct ttacaatcaa tttaatccag ctgttttaag acttataaag
    37801 actgttatag acaatgcaca taaagaaggc aaatgggcag gtatgtgtgg agaatctgct
    37861 ggagaccaaa aaatgatacc aatactttta ggtatgggat tagacgagtt ctctatgtct
    37921 ccaatatcaa tacttcctgc tagaaagtta ataacttcag ttaaagagtc agatatgaaa
    37981 aaattagctg atgatgtact taatatgggt actgctgaag aaataaaaag ctatatagaa
    38041 aagactttta atatataatt aatgttatat agttactaaa attcattttt ctaaataaca
    38101 aaattatatt ttacgaatta aaaaggagat gtttcaaaat aaaaatttga agcatctctt
    38161 ttttataaaa gattactaag aattacttaa tctttgtaat agtcattttg tgaaaaagca
    38221 aaactgcatt gtggctatag tatatatgga tgttattatc aataaaagta ctattaaaat
    38281 gaagattcat tctcaaatga tatcaaaagt agttgtgatg gagtaagata atattttgtg
    38341 atttaatagt aaaaattaaa aaaatatggt attgaaaaat aattaaaagt atttaataat
    38401 agaattaggg aagaataagt ttataagtaa aaataattga ttactagtta ataaaataaa
    38461 tgtgatatcc aaataaatcc taaatctaat ttgagtttta atatagatag tctaaagttt
    38521 gattattaaa gatttaattg taagttgtta cagttgatga tattgattag agattaaagt
    38581 ttagagtaga aagttacctt aaatttaaaa atgcaagata acccaatcta aaaattataa
    38641 tcactcaata ggtttaagga tttatttgtt tattataaat aggagggtgt ctcaaaatga
    38701 actttttagt ttatgaggca ctctctttta tatagaatta aatatatttt attatttcaa
    38761 caatgaaaaa gaagcttatc tctattttga gacagcctct ttgtatacta ttattaattt
    38821 aatcaataac ataatttaaa actatattat tagttaagat ttcctgcttt attagtaaat
    38881 aattctttaa tagcattgtt tctggaaact aaatcgttat cagagttgtt tgtttttttc
    38941 ataatcactg aataacgttt tttatttata aaaaatatta aaatcttatc atcatcaaaa
    39001 ttgtattctt tatatctgtc aatagactca taacctagat ttagaatgtt tttgtctttt
    39061 atactatcta catctaaaat atatgatggg tcagccttta gtaatatatt aattaaacat
    39121 ttttcttcac cagcacagaa taactccatc ttacttgata tagatttaga ttgctctgaa
    39181 gttatttttg caggaataag gttgtcattg tcatctctta gaagataacc atgtgtgtct
    39241 tgttgatata ctaaattaac ctttttctta ggaacactaa tcattttatc taaatgtaca
    39301 taatgatgat tttcaacaaa accttcattt aatatttcaa caaagttatt aattttacct
    39361 aggcaaaaag attctataga ttctttacag aatttatttg taaatggtat tatgtttacg
    39421 ttttcctcgt ctgtattcca tgctatagca taatccaacg aatatacttc ttcctctata
    39481 tctgcaaaat tatattgtac tatgtttcct ttcaaaatta ctc
//
LOCUS       DAEHWO010000034        38798 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEHWO010000034 DAEHWO010000000
VERSION     DAEHWO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38798
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.034"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(110..514)
                     /locus_tag="KNP54_002046"
     CDS             complement(110..514)
                     /locus_tag="KNP54_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBF0892947.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            complement(706..1893)
                     /locus_tag="KNP54_002047"
     CDS             complement(706..1893)
                     /locus_tag="KNP54_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBF0892948.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(1925..2350)
                     /locus_tag="KNP54_002048"
     CDS             complement(1925..2350)
                     /locus_tag="KNP54_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892949.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIG
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVHKEE"
     gene            complement(2478..2630)
                     /locus_tag="KNP54_002049"
     CDS             complement(2478..2630)
                     /locus_tag="KNP54_002049"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892950.1"
                     /translation="MRRDNNLLMKDYKYKGYFEGVEIFDNVNDLNLNTLTTVSRFVFV
                     FLFTIT"
     gene            2828..3577
                     /locus_tag="KNP54_002050"
     CDS             2828..3577
                     /locus_tag="KNP54_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBF0892951.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELIST
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFEIITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(3753..4118)
                     /locus_tag="KNP54_002051"
     CDS             complement(3753..4118)
                     /locus_tag="KNP54_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBF0892952.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWRSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(4134..4910)
                     /locus_tag="KNP54_002052"
     CDS             complement(4134..4910)
                     /locus_tag="KNP54_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0892953.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(5321..6748)
                     /gene="ascB"
                     /locus_tag="KNP54_002053"
     CDS             complement(5321..6748)
                     /gene="ascB"
                     /locus_tag="KNP54_002053"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBF0892954.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFVVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(6809..8737)
                     /locus_tag="KNP54_002054"
     CDS             complement(6809..8737)
                     /locus_tag="KNP54_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0892955.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(8882..9724)
                     /locus_tag="KNP54_002055"
     CDS             complement(8882..9724)
                     /locus_tag="KNP54_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0892956.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(10071..11441)
                     /locus_tag="KNP54_002056"
     CDS             complement(10071..11441)
                     /locus_tag="KNP54_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBF0892957.1"
                     /translation="MKNKYEDVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIENFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            complement(11480..12151)
                     /gene="pgmB"
                     /locus_tag="KNP54_002057"
     CDS             complement(11480..12151)
                     /gene="pgmB"
                     /locus_tag="KNP54_002057"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBF0892958.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     INREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGVKDEFDCIVNPSLLKRGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            complement(12153..14543)
                     /locus_tag="KNP54_002058"
     CDS             complement(12153..14543)
                     /locus_tag="KNP54_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBF0892959.1"
                     /translation="MSLIFTTKDQLVELGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGVRTYFEATNDEEFMMQNGLEILIETSRFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVFVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(14569..16017)
                     /locus_tag="KNP54_002059"
     CDS             complement(14569..16017)
                     /locus_tag="KNP54_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBF0892960.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKN
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MSYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(16422..17309)
                     /locus_tag="KNP54_002060"
     CDS             complement(16422..17309)
                     /locus_tag="KNP54_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0892961.1"
                     /translation="MAIYLEMPKLIHEFPFRTLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(17409..17858)
                     /locus_tag="KNP54_002061"
     CDS             complement(17409..17858)
                     /locus_tag="KNP54_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0892962.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(17848..19755)
                     /locus_tag="KNP54_002062"
     CDS             complement(17848..19755)
                     /locus_tag="KNP54_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0892963.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(20023..21918)
                     /locus_tag="KNP54_002063"
     CDS             complement(20023..21918)
                     /locus_tag="KNP54_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0892964.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(21954..22832)
                     /locus_tag="KNP54_002064"
     CDS             complement(21954..22832)
                     /locus_tag="KNP54_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBF0892965.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(23375..23545)
                     /locus_tag="KNP54_002065"
     CDS             complement(23375..23545)
                     /locus_tag="KNP54_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892966.1"
                     /translation="MSALLYGVCNKSISVSIVINMQEFKIGVSMAYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(23942..24154)
                     /locus_tag="KNP54_002066"
     CDS             complement(23942..24154)
                     /locus_tag="KNP54_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0892967.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(24155..24571)
                     /locus_tag="KNP54_002067"
     CDS             complement(24155..24571)
                     /locus_tag="KNP54_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892968.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(24639..25052)
                     /locus_tag="KNP54_002068"
     CDS             complement(24639..25052)
                     /locus_tag="KNP54_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892969.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(25885..26514)
                     /locus_tag="KNP54_002069"
     CDS             complement(25885..26514)
                     /locus_tag="KNP54_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBF0892970.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALRQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(26593..27555)
                     /locus_tag="KNP54_002070"
     CDS             complement(26593..27555)
                     /locus_tag="KNP54_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBF0892971.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKVKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVIEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(28317..31832)
                     /gene="cbpA"
                     /locus_tag="KNP54_002071"
     CDS             complement(28317..31832)
                     /gene="cbpA"
                     /locus_tag="KNP54_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBF0892972.1"
                     /translation="MQQKCKKKALSMILSISMGLGPVASFNASNTFADTIEESTNAGN
                     AEGGTNAGNAEGDTNAGDAEGDTNAGDAEGDTNAGDAEGDTNAGNAEGDTNAGDAEGD
                     TNAGNAEGDTNAGDAEGDTNAGDAEGDANAVVVEEEATAEEPTSVGDFKISGGEINVD
                     FKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVNIKTASNSPFTL
                     TPDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLIIDDSVVNRDIEGEFIVP
                     EGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGGGNTESGGNIII
                     NGGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGIITAKGAYHGAGIGGGYYTT
                     TKNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNPGTNRGYRILVT
                     GGTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYGDLEKKTKVFMN
                     KISLTYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDAQGILYLWFSDQFKGSEVSV
                     NLVVIDKITGEVLKPDDFYIKDIGSGSQFLKQYEEFTIDDTPPYLIIKRYDGLPFEED
                     VEKSFLDWIFKDGGIPIITPKGEKLTDKKFMTISSQRLNEETMEPDINLGSDDLTKQV
                     DAGKYQLSITSTQFSSIYPFKDAYWGHRAYYKAEIIPADTETSLVVEESKAKTDVFKP
                     TDTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNKGSESHNYSTAS
                     IEWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDMTNVDVDGDGIPDIN
                     IDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNGDGIWKPDKNIDTNGDG
                     NPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDPDNGGNSKPDSG
                     NGGNSKPDSGNGGNSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDPDNGGNSKPD
                     PDNGGNSKPDPDNGGNSKPDIDTDGDGKPNINIDTDGDGKPDINIDTDGDGKPDINID
                     TDGDGKPDINIDIDGDGKPDINIDTDGNGKPDINIDTDESLDSNVGQNVQTGDQSNIM
                     LDLALMFISLFFLIKNLTNKYLRRK"
     gene            32101..32673
                     /locus_tag="KNP54_002072"
     CDS             32101..32673
                     /locus_tag="KNP54_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HBF0892973.1"
                     /translation="MKKLVKILINIICIITLIFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNIDYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEAFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNSNYEFKDYLNYIT"
     gene            complement(33686..34348)
                     /locus_tag="KNP54_002073"
     CDS             complement(33686..34348)
                     /locus_tag="KNP54_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0892974.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(34365..36920)
                     /locus_tag="KNP54_002074"
     CDS             complement(34365..36920)
                     /locus_tag="KNP54_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0892975.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPHDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKNDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLLRLMGAKKRNIRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGMISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEEGSLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGIENFMSFTFPIKESLLFFAISVFVCLISVVVSNRDFESMNIIEGIKENE"
     gene            complement(37160..37348)
                     /locus_tag="KNP54_002075"
     CDS             complement(37160..37348)
                     /locus_tag="KNP54_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBF0892976.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSGDDIERITKEKYTK"
     gene            complement(37360..37539)
                     /locus_tag="KNP54_002076"
     CDS             complement(37360..37539)
                     /locus_tag="KNP54_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892977.1"
                     /translation="MIHIEISEKEFFRKIEEVFDKGEVNVEVDNLGDIKIQVKKFDDK
                     TKSLELKLIKEFKLK"
     gene            complement(37544..37801)
                     /locus_tag="KNP54_002077"
     CDS             complement(37544..37801)
                     /locus_tag="KNP54_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892978.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQPSQVLH
                     YSITKEKKDTKEILSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            complement(37774..37914)
                     /locus_tag="KNP54_002078"
     CDS             complement(37774..37914)
                     /locus_tag="KNP54_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892979.1"
                     /translation="MVIAISLTLGLITGCTNKVSGTNEKIYTIEQISSIKKTCQRKYQ
                     NQ"
     gene            complement(38061..38798)
                     /locus_tag="KNP54_002079"
                     /pseudo
     CDS             complement(38061..38798)
                     /locus_tag="KNP54_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
BASE COUNT        12583 a         6702 c         4022 g        15491 t
ORIGIN      
        1 acactagtaa gatatactaa tatataaata cttaaattta gttttattta aacgctctag
       61 tgatattttt aaataaattt taataaaaat tattctattt tgtcataaat catttatctg
      121 gcttatattt aagatatatt ggtggatact ttacactttt taattcctca ttacttctta
      181 aaagtttatt attattttcc atatcataaa tttgtaacat tactttattt acatatagag
      241 cataataatt atcactataa aaatattgat actcatatcg agggtcatct ttgtaataca
      301 ctttgtatag tattccttcg taacttgcct tcttggcttt ttcttttgta atacttttta
      361 tattatcttt tgaaatatct tgttttacca tatacttatc aatatatgtt tcagcatctt
      421 tccatggttt aatgcagttt ttatatacaa caaaccctgt tacacttata atacctataa
      481 ttaatactat aaaaataact ttatattttt tcatattaat cctccttcat ttattattta
      541 aaactcgata taatgcacta aaaaaaggat gttatctttt ttattaaaat ataacatccc
      601 tcatatttag catcaatata tatgccccaa ctggtaggtt aaaagacccc actgtcagta
      661 ctttgattaa attacatgta tgtatatata tttttaacaa atctattata tgtcaacttg
      721 tctactatta catataatct gtaatattac atctgctgct ttttttgagc ctcctgcatt
      781 ataaaagctt tttgatagtt tagttgcatt ttctttatat tcattgtcat ttataacttg
      841 aaatactgct tttttaatac tttctgattt atcctctttt aacataattc ctgctcccaa
      901 atgaacaact ctcttagcta ccattctctg ctccgaatgt tgaggaaata ataccatagg
      961 tactccataa tataaacttt cattaacact attcatccca gaatgagtaa caaacacatc
     1021 agttttttga agtatagcaa tctgttcaac actattttta acctcaaaat tatttggtat
     1081 atttcctaaa cttttaatat cagtacttct accaacagac ataatcacat caacatcaga
     1141 atctttaaat gcatttatac agtttttata aaagctaaca tttttattat taattgtacc
     1201 aagcgaaata tatattagct ttctttttct ctctttaggt tcaataatca actttgatac
     1261 tgatggacct acaaatgaat acttactaga gaaggtttct accattggtt gaaattcttt
     1321 tgatgtatat acaatggtat ccgtatcatt atcattagaa actatagaaa taaaattttt
     1381 tacttcatac ccttttcttt gtaaaagctt tattttttta ttaatgcgtc ttacaccaaa
     1441 aatcatacgt ataatttcta taaagttttg tttcatcaac tttgctgtat gtttattaaa
     1501 tgcaaaagtt gttgtagagc atacatatgg aatattaagt ttttgtgcaa ataactttcc
     1561 ccaaaaactt aatgaatctg atacaatgca atctggatta aaatctttaa gttctctaca
     1621 aactttttca tctaaagaaa tagtagtatc tactatcatc tcaattaatc caggaaaatc
     1681 cttaccaatt tttttctcat ctccagggag taattctgga aggtatttat cacaacaaat
     1741 aaattttgct ccagcacctt caattttatc tttaaattca ttaaaagaat aatacaatac
     1801 ctcatttcct ctatccacta attcacgaac tacttcaata gtaggattag tatgaccata
     1861 tgcaggaatg ctaaaaaata ctattttact catatttcat acctcctttt ataatttttt
     1921 taaatcattc ttctttatgt actactccca catgacctat aaaatttatc aaatcacgtt
     1981 gatgaacaat tcctaatcct ctttcctcat ctccaagtac caataattta tctcctgcat
     2041 ttatattaaa tacttctctt gcttcttttg gaatgacaat ctgaccacgt tcaccaacta
     2101 caactgctcc aaagaaaaac tttcctttag gaggtactat aatacctgtt ttttcttccg
     2161 aatgattaac taagtcatct agtttaacat tgtacaattt tgcaagttta atgcaactac
     2221 ctatatcagg aatagattct ccactttccc attttgctat tgattgtcta gaaacattaa
     2281 gtttttcagc taattcttct tgtgtatact gattgatttt tcttagactt tttaaattct
     2341 cattaatcat atttttcata cctcctatgt ttataatatt ggatttatta tttaaattct
     2401 atcaactaat cttaacattc atatatatat ttatatactt ttattatata aatttattgt
     2461 tcaggtaaca tatttcctta agttatcgta aacaaaaaaa caaacacaaa tctactaact
     2521 gttgttaaag tatttaagtt aaggtcattt acattatcaa atatttctac accttcaaaa
     2581 taacctttat atttataatc tttcataagc aaattattat cccttctcat atacaagtcc
     2641 agttgatgtc ttgttgctaa atttaatggt aatcaaattc tttaccaata agtataaaaa
     2701 ttactaatgt gttataattt tcttaactac taaattttac atacatttga atagaatata
     2761 tcaataaatt actataataa ataaaaaatt aagagttaaa ataaaaaata gttagggaga
     2821 tattattatg attttatatt ttagcggaac tggtaatagc cgatatgtgg ctcgtaaaat
     2881 tgcacaagaa ttaaatgatg aactgatatc actaaatcaa cttataaaag aggaaaaaac
     2941 agatgaatta atatcaacag ataaaccatt catatttgta tgtcctactt atgcatggag
     3001 attgccaata gtggttacgg attttataaa agaaacaaaa tttctaggaa gcaacagagt
     3061 ttactttgta atgacttgtg gtggagatac agcaaaatcc ataaactata ttcaaaaact
     3121 atgtaaatac aaggaatggc aattaaaagg tatggcagaa attaaaatgc cagagaatta
     3181 tatagcttta ttttctacaa cagacaaaga aacatcaaaa caaatgatta aagaagcaga
     3241 taaacaaata tataggatta tttctgatat acgaaatgaa aatgaatttg aaattattac
     3301 tcctagtggc ttaggaggta caattaaaag tggtataata aatacagttt tttataagac
     3361 aattattagt gccaaaggat ttcattatac tgataaatgc attggctgtg gaaaatgtgt
     3421 agagctatgt cctttaaata atattaattt aaaaaacaaa aaaccagttt ggaaaaataa
     3481 ctgtactcat tgtatggcat gtatttgtgg ttgccccact gaagctattg agtataaaaa
     3541 taaaactcaa aacagagaaa gatactattt agaataatat attcttaata tttaaaccat
     3601 tataaaatga actataccca ttgttttata cagttttaca tattttaact gtctcctaag
     3661 atgggtatag ttcaaaagat agtgtctcaa agtgaacttt ttagttcttt ttagttccta
     3721 aatcaatctt tttgtattaa atcaagtata atttaatcac cttttcttat atcattttca
     3781 ctaatatgtt gtattccaac aaatataaga tttattagct ctgttagtga cctccattgt
     3841 gatttttttg aatcaagata ataataattt tttgttcctt ctctacgcaa attaacaatc
     3901 tctgcttctt ttaatatctt aagatgatga gatacagcag gacgagaaag atgtgttttt
     3961 tttgtgattt ctcccactcg tataccatta aaatcactct ctaagagagc aattaaaatc
     4021 aattgtctag tctcatcacc catagcagag atagctttgc gacattcttt aaatttagac
     4081 gttatttctt gcattctttg ttgacattct ttttccataa aatccaccct ctcttataag
     4141 tatctaacag ttgctacttc tttctgtgca gtacgtctat atttaacatc tgggtatcca
     4201 attactaatg ttgtaagaac atgattactg cgttttagac ctaaaagctt ttttaatttt
     4261 ggcgaattat ttgctacatc tgaaaaatat ccactaaata aaacacctag gccataagac
     4321 tctgccatta atgccatatt tgatgctgca agtgaaccac taatcttatc ttttgtaatt
     4381 atcattattg caataggagc atgcttaaag aaaaagttat cgtcaatctc aacttctttt
     4441 gaatatttaa tagctatatt tgcaataggt tttatttttc taaaaaattt cactgcttcg
     4501 ttttcataaa ttgacttttt attgtctaaa acaatatatg atacatcttg tgaattttta
     4561 gcactagggg tatacctacc tgcctcaata atttgcttta taatttctga agaaacttct
     4621 ttgtctttaa atttacgtat acttcttcta gatttaattg ccattagtaa ttcatctgaa
     4681 tctagctttg gcttatttgt aagttctata ggaggttcat caaatcctgt caaggtaata
     4741 gcttttgtgg gacatattgc tgcacaatgt ccacacatta gacaatcttg ttttttaatt
     4801 actgactttt tattttctat aattatattg tttactggac aatcattttt acaaagccca
     4861 catccaatgc aaagttcttt gtcaacttct attatatgtt ggtatttcat attcattcat
     4921 ctacctttcg tttattagtt taaactatta taacacgtag acatttttta tattcattgg
     4981 taaagaattt gattaccatt aaatttttaa tttctctatt aaataaattt ttcatagaat
     5041 tttaaagtat catagtttat acataataaa aaagacaagc ttaaaaccta agcttgcctt
     5101 tttcatcttt tattacaaag taaattgcac ttacttccca tacttcttaa caattttatt
     5161 ttctaaaatt ttatttgtga atcatactat tgcataaata caatgtaaaa taattctgta
     5221 ttgattttct atagttaaaa aagttaaaaa ttatacttat tattaatttt tatactcttc
     5281 ttatttaata caaatttctt atttaacata gatttcttgt ctaatataaa tcttcaccat
     5341 ttgaagcaat tactttctta taccattcaa aacttttctt tttcattctt cttagacttc
     5401 cattaccact attgtctcta tctacatata taaatccata acgcttttcc atttcacctg
     5461 taccagcact tactaaatca ataggtgccc atgtagtata acctaataaa tcgaccccat
     5521 ctatagaaac tgcatcatgc atagctttta tatgttctct tatataatca attctgtaat
     5581 catcttctac ataaccattt tcatcagcta tatctttagc acctaatcca ttttctacaa
     5641 caaatagtgg cttttcatat ctatcatata catgatttag tgtaattctc aaacctaatg
     5701 ggtcaattgg ccatccccat tgactgtatg aaagatatgg atttttagca gatgtaaata
     5761 tgtttccttc agccatatca tctgcatttt catcggttct aacacaacgg ctattgtaat
     5821 atgaaaatga aataaaatct actgtatatt tattcaataa ttcaatatca ccaggttcca
     5881 tttctggtgt aatacctttt tgctccatat actttaacgc atagttagga tatttacctt
     5941 tagattgtac atccacaaag aagtaatttt ctctatctaa ctttgtagct tcccatacat
     6001 cattaggatt acaactataa ggatatacac ttccagctgc aaacatacat ccaattaagt
     6061 tatttgaatc aacttcatgt gctattttag ttgcaattgc actagctaca agctcatgat
     6121 gggcagcttg atattttatc ttttcaacat cttcaccttc ttcaaagcaa ataccagcac
     6181 ccataaatgg agcatgtaaa atcatattta tttcattgaa agttagccag tacttcacta
     6241 atcctttata tcttctaaag ataacattgc ataatttctc atagaaacct atcatttttc
     6301 gattacgcca tgcaccatac tttttaacta aatgcattgg acaatcaaag tgtgtaatag
     6361 tgactaaagg ctctatttta tattttttac actccttaaa tatattttca taaaattgaa
     6421 gtcccttttc atttggtgtt tcttcatcac cttttggaaa tattcgactc catgcaatgc
     6481 tcattctata tactttaaat cccatttcag caaataactt tatatcttct ttataattat
     6541 gatacatatc aataccagtt ttagctggat aataatgctc atcatcaaaa tcaaacattt
     6601 ttagtttccc tgtaataact gctgttctat cttttcctgt tggacataca tctacatttg
     6661 ccaatcctct ttcgtcttca ttgtatccac cttcacattg attggccgca gtagctcctc
     6721 cccataaaaa atcattctta aaactcatag tcaaagcctc ctaaaattat aaccaaagca
     6781 ctagattatg ctaatacctc aatctttact aaaataagac tgtaattaga ttgtcttcta
     6841 attcaatatt tttactttct gtttctacta catctaaaaa ttgtgatgaa tttgtaataa
     6901 caattggagt tacagtacta taccccaact cttttattgc atcaacatca aagtttaata
     6961 tagtttgacc ttttgtaatt ctatcacctt gttttataca tgcctcaaaa cctcttccct
     7021 ctaattgaat agtatttaat ccaatatgaa taagcacttc aacacctgta tcagaaagaa
     7081 tccctatagc atgtagacta ggaaataagg ttgtaactac cccatctact ggagcaacta
     7141 cttttccatc actaggtatt attgccaccc cttgacctag tacaccagat gcaaatgctg
     7201 catcctctat atcacttaat tttaatactt caccttttat aggacttgtt actatttctc
     7261 tttctaattt agtagacttg acttctttta tttcttcttt acccttattt cttacttttt
     7321 tagactcttc tactttctca tctttatata aaatcatagt taatacaaaa gctacgacca
     7381 ttgatatagc tataccagaa agagctacta ttaagttacc cattccccca tctggttcaa
     7441 tcattgctgg aagttcaaat attcccattc ctccagttat aaattttcta agattaaaga
     7501 atccatagaa agcgcctcca ataccactag caatacaact tattataaat ggtttcttta
     7561 aaggcaataa tattccataa attgctggct ctgtaactcc aaatatacca gatataaagt
     7621 ttggtattgc catctctttt agttttttat ctttagtctt gaaaaatatt gccaacacaa
     7681 ctgccgaact tgcaaatgta caggcaaaga atggcatcat aacattatca tatcctaaag
     7741 tcataacatt gtttatatat acaggaataa atccccagtg cataccaaaa ataacaagaa
     7801 tttgccaagt aaatcctact atagcacctg ccaatagtgg actaaaatct cttattgaaa
     7861 ttacaatttg tgaaataagt gtagaaccaa atgttgctat agggcctata actataagtg
     7921 caacaggcac tgttattaat aatgtaagca ttggcacaaa gaaaaactta actaaatttg
     7981 gaacacactt attaaataat ttttcacacc tagaagcaaa atacactata aatataattg
     8041 gtacgactgt tccagtataa tcaattgata caattggtag tccaaagaaa tcaatatata
     8101 ctggtgatgc aaacattgtt cctttaaata aagtgtacat cacatctgct cctgctgata
     8161 tactgctacc ttgtatagca ggataacata ctgcagctcc tagtgctaat cccaacattg
     8221 gttttaatcc aaacttctta gctgaagtat atcctaagaa caaaggaagg aatgtaaata
     8281 atgcatctcc cgctgcattt attaccatat aaccaccaga tacatcacta tataatccca
     8341 ttgctacaaa taatgcatta aatcctttca acataccaca agctgccatt attcctaaca
     8401 ctggctgaaa aattcctgat attatatcta tacctttatc tagtatatta cctgattttt
     8461 tagtttctga acttgtactt gaatcatcta aaccaattat ttcaactaca tctttataga
     8521 cagcttcaac atgatttcct ataactactt gatattgtcc tccacttttc attacagtaa
     8581 caataccttc catgtttttt aatacattgt catttgctat actttcatct tttaaagtaa
     8641 aacgtaatct tgtaatacag tgtactaatc cactaatatt ttcttttcca ccaacattgt
     8701 ttactatctc ttgtgctaat tgtttgtatt ttcccatttt tctcctccat atttcgttta
     8761 aattaatttt ttgaaatttg aaggtttggc caactcaatg ttaccatcca accataagta
     8821 taattttgtt agtatcactc ctttcaatca ttcttaatat actgctgaaa aattatttca
     8881 cttacatatt tgagtcttta actactttag ctaaatgtat tgttaaatat ataagctcat
     8941 catctgttaa tatgtagtta tattgttttt taatgaaatt tttaatttta actacacatt
     9001 caaactcttt attatattta gatttaataa tgcttagtaa ttctttgtct gtctcacctt
     9061 catgtgcact atctaaaagc aatctttgcg caaaaaactt taaatgcatt ataaatctat
     9121 aataaaacac tgattcttca tgaaattcta tcctaaaatg atacctaact atgctaagta
     9181 cttcttgtat taacttcgta atatcagatg ccaaagtatg accttcactt aactgagcat
     9241 tcactatatg aaaggctata aatccagcct catcttctgg taattttata cctgttttgt
     9301 tttcaataat atctagtgct ttcattccaa tttcaaactc ttctttataa aatcttttaa
     9361 tttcccaaag gattgcattt tttacattta ttccttcttt cattctttga attgcagaat
     9421 atgtatggtc acttaaggat atgtaaatac tttcatttag cttcttgttt aactttattt
     9481 gtgcgtattc tataatttca cttgataatt tcatgtgttc tataggaata ttattgagta
     9541 attcttgtag tttgtttgat atttctttat ttgatattct aaatacttta tttactttag
     9601 ttttatctat tagattgcct tttgattttt gataaccaat tcctttaccc ataacgataa
     9661 cttcttcatc attatcatct aatgtgatta caacattatt gtttaatatc ttattaatta
     9721 tcatgattat cctcctttta agcataaaaa aagcttatcc ataataatgg gcatactcct
     9781 tcctaggata ctgctattat taatgaataa gcttagcttg tacttaaaca attactacct
     9841 aattccaatt aatatgataa aacatcagac atattttgtc aactttttat ttccatatac
     9901 ttcatcaatc ttttatgttg ctttttgtca gttataataa ttattcttat taatattaac
     9961 ttatttcttt gcatcaatat aaatacaaaa caagttatag tcaataataa taaaaattct
    10021 attaatgtaa atagttaata ttatacttcc tctactacat tatctgtact ttatttaaca
    10081 tttttttcaa ctccaaaaac atatgtcata ataaatggag caaccaatgc tataaatata
    10141 actataagtc catttactat atttgaaatc cccttttccc ctgataatcc aagtactgcc
    10201 attatactat tttgtggaac atataaagtc acatgagtaa ttcctgcaaa taaccctgcg
    10261 attcctgctc ctatagatgc taacatagca ggttttttaa gtttcaatgt aactccataa
    10321 agagctggtt cagttatacc cataatagct gatatccatg cagctgatgc taactgtttc
    10381 atcttactat ctttgcttct taatgctaca gctaatgttg cgccaccttg cgctaaatta
    10441 gcacaaactt gagatattaa tattagcgat tcttgtcctg tagttgcaaa tgctgatatg
    10501 aatataggag tcaatgcatg atgcatccct gtcataacga taaatggcat tgcagctgct
    10561 aataaacaaa ccattataaa tcctaacctt ccttgtagta aatttattat actagctaat
    10621 ccctctccta agaaatttcc tattggtcca attactatta atgctattgg cgcacttatt
    10681 aataatacta aagttggatt taaaattgtt tttaacatgc taggtgttaa tttatcaatg
    10741 aaattttcta tatatgacat catccatact gttaaaagtg cagggataac agatgctgca
    10801 tatataacac cttgaattgg tactcctata aatgatatag ggtccccact tgatacccat
    10861 gcagagaaat ttggatgtaa aaacacacct actactataa ctgctattga tgtattaaca
    10921 ttaaattttt tagctgcatt tattgcaagt attataggca taaagtaaaa tgctacatct
    10981 cctattatat ctaatactct atatgtactt gaatttgatg atagccaatt aaaagtggtg
    11041 caaagagata atataacttt tatcatccca gatgctgtaa gggctggtat cataggtgtc
    11101 atacaaccag ttattgtatc tattatatta tttaaaatac tatttttttt atttttattt
    11161 tttatatcgc ttttaatatc tcctgtggta tttatcccct tatttattat tgcattaaat
    11221 acaacaccta cctcattacc tattatgacc tgatattgag ttgaagttga gtttactcca
    11281 actaccttat ctatagattt taatttatct gcattgactt tcttttcatc ttttaagatg
    11341 aaccttaatc gtgtcataca atgagttaag tcaattatat tatcttttcc tccaagtcca
    11401 tcaattatca attgagctac atcttcatat ttattcttca taccttatcc tctcttttaa
    11461 aataattttt aatataattt taatccaaat taatcttttt actccaagct tgtaatagtg
    11521 tattgtaatt taataagcta gtatcttcta caatatggtc acattttcct agtacttctt
    11581 ttttccccac accaattgat gtcatattgg cagcatttat agctttaata cccgaataag
    11641 aatcttctat tcctacacaa tcatattgtt ttaaatttag catcttgctc ccttcaataa
    11701 aaatatcagg atatggtttt ccccttttta ataaagatgg atttactata caatcaaatt
    11761 catcttttac tcccaaagat tctaatatcc taggtgcatt cttactagca gatgctattc
    11821 ccaatttcac attatttttt ttaagttctt ttataagctc atttatccct ggtaatatat
    11881 ctttatatgt taatgagttt attaacttta tataaatgtt atttttttct tcacacacct
    11941 ttaacttttc ctctttagta taactatcta ctttattagc agataacaat attttatcta
    12001 atgattcttc cctgtttatg ccttttaatt tttcattaaa agtttcatct atttctatat
    12061 ctagcgattt tgctatctca tgccaagctt caaaatgata cttagcagta tctgttataa
    12121 ctccatcaag atcaaataag actgctttca tattaattac tccctttaaa acaattatta
    12181 acttctatta tgttctttga taattttatt tctttattat catgtaatat ggttatattt
    12241 ctacctttga ttaacttata ataagattta tattcttcta tatttacaaa aactaaatta
    12301 tctctaaata atatattaaa tttaatattt ttccagtgtt taggtatcct tggttcaaaa
    12361 cttaatttat cattttttat tttcattcct gcaaatccat atactaaact catccatgtt
    12421 ccacccatat tagcagcatg tattccatca cttgtatttt tttgtaggtt attaatatcc
    12481 attaatgctg tgtccataaa atagttataa gctttttcat gatttccaat ttcacttgcc
    12541 atcattccaa atattgacct tgacaaagat gaatcatgag tagttatttt ttcatagtat
    12601 tcaaaatctc tcttcttttg ttctaagcta aactcatcag ggaaaagcaa cgctgaaagt
    12661 acagtatctg cttgtttatt tacttgatat ctatatattg ttaatggatg ataatggaga
    12721 agtaatggat atttttcttt tggtgtattt ttaaaatccc atactgattt ttctaaaaat
    12781 gaatcgtctt gtttgcttat tttcttctct tcatcatatg gtaaatacat attttgagcg
    12841 gcatttatcc agtttttcac ttcatattct tgtaatttaa cttttctaaa tacttcattt
    12901 gaaaataaat tatgcttaaa tttatctacc atctgtactg catatattaa attatactta
    12961 gccattaaat tagtgtagta attattgttt actattgctg tatattcatc tggtcctgtt
    13021 actccattta tacagaattt attatttttt gattctatat aatctccaaa ttcaacccaa
    13081 aatcttgatg tttctataag aatttctaag ccattttgca tcataaattc ttcatcatta
    13141 gttgcttcaa aatacgttct aacaccataa gctatatctg catttatatg aaactgtgct
    13201 gttcctgctg gataatatgc actgcattca ttaccattta tagttctcca tgaatataag
    13261 caacctttat ttattccaag ttctctagct ctttctcttg atgcatctaa gattgagtat
    13321 ctataatcta ataaagctct agcaatggat ggttgagtat atataaaaaa tggtaatata
    13381 tacatttctg tatcccagaa ataatgcccc tcatagccat cacctgtaag accttttgct
    13441 gatatattag tctttccatc tcttcctgct gattgataaa tatgaaataa attggttttt
    13501 atccccagtt gaagagtttt atcgccttca atctctacat cagaggttgt ccaaaactca
    13561 ttcattttct ttctctgaat atttttgact ttatcaaatc caatattaca tgcttctctt
    13621 aaaaccaatt ctaatgattt taaatgtgct tctgattcta aacattttaa cgactccaga
    13681 cattctaatg attttaaacg ttcttcattt agatttaaat cagaatatac tctactatag
    13741 cctacaacaa tttctaaatt taacctttca tcttttttgg catagacttc tatttctcgc
    13801 tcaatacatt catctgaaac attataggtc tcatttgtaa tatttccaca agtaatatat
    13861 gaatcaaacc cacaccataa ccctaatcta cttctttctg taactaaatt cataaaatac
    13921 ttattgttat atttttttac attaatttta aattgcttct tatttataga tgccactctt
    13981 gggtcatcta ctttttcaca attaaacttc tccatactat tttccatttt atttttaaat
    14041 tttatttttc cattaaaatt caatggtgtt attgtatatg aaatcatcat taattcttct
    14101 atatcttgtg atactaatct ttctatagat actttaactt ttctaccacg agagttttcc
    14161 catataaatg aacgtttaag aatcccttca tttaaatcta gtatcctagt atgttcactt
    14221 gtaatacctt ttgataaatc aaagcaatct ccttcaatag agaaatttac tatatgagca
    14281 ttaggtaact tacagatagt ctgattttgt tttgcatagc cataagcgct ttctccatat
    14341 gtaattggag attcttcata aaatccattt acatatgtac ccatattatc tacatactca
    14401 ttattaaaat cagactcttc aatattccct ctaactccta aatgtccatt agctagtgta
    14461 aacaacgttt cattggattt tattgtatcc ttactaaacc ctagctctac aagttggtcc
    14521 ttagtagtaa atattaaact cataataaca ctcctttctt aaaatgaatt atgcatgagt
    14581 ttccatatca ttaaataaaa tttctccatc tgtttctatt acttttttat accaaaaagc
    14641 actttgtttt ttagttcttt taaatgagcc tcttccatag tcatcagaat caacatgaat
    14701 tatgccatat cgttttgtca tctttccttc acttacactg gttacatcta tacatcccca
    14761 cataagatat cctataagct ctattccatc ttcatttact ccaagaatca tatttttaat
    14821 atgttctttc atgtaatcta tacgataatc atcaattatt tttccatctt catttacaat
    14881 atcttgagta cccagtccat tttctactat aaataaaggt aactgatacc tttcatataa
    14941 ctgattcata gttattctta accctacagg gtcgttttgc catacactat ttgattttgg
    15001 aagatatgga ttttttatgg tttctggtcc gtttgccttt gatttttcta aaccttcagc
    15061 tctagctgaa ctacaagcac tagaataata gctaaaagat acaaaatcta cagtattatc
    15121 cttaagtgtt gataaatctt cctcttttat tattaatttt atttgatttg attttaaata
    15181 ataactcata aagcttggat acacacccct aacttgaaca tcagaaaaaa acaaattatg
    15241 cctctcatgc tctaaagttg caaatacatc ttctggttta catgtgtatg gatatgtttt
    15301 tccagcagct aacatacacc caaacttaaa ttctttattt atataccttc ctatttctat
    15361 agtttttgca ttagctaata attgatggtg tgctgcttga tattttttct gaagttgatt
    15421 ttcatcagct ataaaagtta acccagcacc tatatatgga atatgcatta tcatattcat
    15481 ttcgttaaaa ggaatccagt atttgacatc atctttatat cttttcatca aaatttcagc
    15541 atattttaca tataaattaa ccactcttct atcagcccac ccagaatatt tttcaactag
    15601 agaataaggt atatcaaagt ggcttatcgt tattaatggc tctatattat atttttttaa
    15661 ttcttttatt atattatcat aaagttgtaa tcccttttca tttggttcac tttcttctcc
    15721 tgttgggaat attcttgacc aagatataga aaatctaaaa catttaaaac ctatttctgc
    15781 taacattgct atatcttctt tgtaattttc acaaaattta atccctatat gacttggata
    15841 gtattgatta ttttcattta aaatattatc ctcatctaaa catacatttt ttaatctctt
    15901 atcatttaat gggagtttat caaactgaga taaacctttt cctccatcta aataaaatcc
    15961 ttcactttga ttggctgaaa ttgcccctcc ccataaaaaa tctttcccta atttcatgca
    16021 tctacctctt tcacagtata aaattttata atttctatct catatttagt tataagattt
    16081 ttttcatact atacctttta aataattcaa tttaaaaatc caattatatt ttttactcac
    16141 tataattaat attgtctatt ttcaatactt tcatattaaa tatcaatatt agatatctat
    16201 gtatataatt atatatatag caaatacatt tttatatcct cattattgtt atcttattct
    16261 catatattgc tgtatattta tatatataaa aggatttatt tcgaaataga ggttgtattg
    16321 agaactaaaa tttagacttt ataaatgaat ggaattttca ttgttgaaat actgaaaata
    16381 tatttgattt catataaaag aaagtgcctc atgaactaag ttcattttga gacactccct
    16441 tttttctcca agctattata tcttttttta aattctaatg gagagactcc aattttttct
    16501 ttaaatactc tgtaaaaagt ttttgtactt ccaaaaccaa cttcttcaac caaatctaca
    16561 atggatatat tgttattaag taatatccac tttgcttttt ctaatctata ttcatttaaa
    16621 aaagttataa atgtttttcc tgtatttttt ttgaaaaatt tagtaaaata atatacacta
    16681 aatcctactt cataagacac atcttctaat tttataggtt gtttataatt tttttctaca
    16741 tatttgaata tattgttcaa tctctctaat atctctttag agtttatttc atattctact
    16801 gtattttctt caatttctct aggaatctgt ctatataata taggaattaa attatacatt
    16861 ttacctttta ttgcataact atatccttct attttgtata ggtcttcatt gtagatatct
    16921 atcaatatat cgaaaactga ctttcttatt tttgctgacc aatctctact acattttttt
    16981 atactactga ataaattaat taagctttct ttctcctcat ttaataaaat taaatcatta
    17041 aaaaaagata tatcaaattg aaatactaat ctttcacttc ccggtgatgg cagtatataa
    17101 tgaatatctc ctccttttat tatcactatc tcgccttttt ttaattgcat aggcttgtca
    17161 tttataaata gatttactac accttctgtt ataagtaata tttctatttc cttatgccag
    17221 tgtggtgttg ttaatacttc tccttcattt gatagagtac gaaaaggaaa ttcatgtatt
    17281 aatttaggca tttctaaata tattgccata tatatcctct cctctctagt gtctaaaaat
    17341 taatctatac tatttaaaag aatacacatt ttattttaaa aacctcaaat ttataattta
    17401 tacaatacct acacttcata aaatatatct aatatttctt tttttgtatg tgcatttaaa
    17461 agtctttcac ctatattttt accacctaaa atgtaagcta ttttagatat taatatcata
    17521 tcttcattac ctccagattg tggcatagca aacataatta ttacctttac aggtaagcca
    17581 tctatacttg gccaatctac acctttttta gatttaccta ttactatgga tgccttcttt
    17641 acatattttg tttttccatg tggcatggcc atttgataac ctatactagt agagcctatt
    17701 ttttctctat gttttaatgc ctttataaac ttacttttta aagttatact tcctgtatcg
    17761 tataatttat ctactaattc ctgtattatg ccttcttttg tagttgattt caaatctaaa
    17821 ataatgcttt cttctgttaa tatttctcta atttccattt gttttctcca atagattatt
    17881 cttaaataat attttaatat cctctttgct cttgcaatct attatatagt ttatatagtt
    17941 cttttgccta tataaatttg atatttccat taaaatattc tttaaaaaac tttgattact
    18001 aatttctaaa taaatatcaa tcgttctagt aacattattg atattcatta tccctttatt
    18061 taatttactt tgcttatgta tatatatatt taaatctttt cctaatgaaa tagattcata
    18121 tttactccct aaattcacac ctattaaact ttccatctga gctacatcaa aattaaaata
    18181 tatattatct tctaaataca ttcctaataa gtttgtatct aagttcatac tttttttagg
    18241 tttagaaagt aaagcatttt ttatattatt aatatcactt tccattaata gtactgatac
    18301 aactatatgt aatttatctt tcaaatctaa gtttacagta gatattacaa agtctacatc
    18361 atctaaattt cgcttactca actgatgcat aggaactata tcaactatag tccattcagg
    18421 aaattctctt tttaatctgg ctgcaaggag ctgagatgtt ccatatcctg tatgacaaac
    18481 tactattact cttttactac tcatatttct ttctattgcc gcttgaaaat atgtggcaag
    18541 atacgaaact tcatctatac taatattctt cagattatca tactctgtca taatatttat
    18601 agtcatcata cataatccca gcacatctga aaatcgctct tgtatctctc ctaacaacgg
    18661 gttttttatt tggatatcat atcttaatct gtttaacata ggccttacat gagatgctag
    18721 acttttctgt agtaagtcat catttttgag atttatattt aaaaatcgtg acatattctc
    18781 tatcattata gatgaaactt tttcactttc acttaatcta tctgattcat cattgtaact
    18841 actattattt tcgctactaa atccagatga taccaaaaaa atatatatgt acataatttc
    18901 atctttcgtt atttttactc tgtatctatt ttctatctta tctataagtg tagtgacatt
    18961 tttatatact aactcgtcca aattatctac agaaatttct ctttcttcct gagattctat
    19021 ttgattacct tcttcgattc tctttaaaca tataagtata tgggtaatta aatttatata
    19081 gtagggctga tttatagtat atcctaaatt gtattctaat tctgtaatta tagtttctac
    19141 aaatataata gaatcaatat caaataaatt tatcaatgca ctaaatgtag cagaatctaa
    19201 tcttgttaac tcagatatat catgttgttc ataattttca tctaataaat catccatcat
    19261 tttggcaatc gatttcctta tatccacttc tttacctata atcttagttc cttctaaagt
    19321 tttattaagt tttaaattgt attcttttat ccatgcctct atatatttaa aatcatttac
    19381 tatagaagtt ttacttacat aatatttatc tgctaactga tttattgaag ttatattatt
    19441 tgaatttagc aataaatact ttaaaatctc cattcttctc tgctctactg ataaagattt
    19501 attttccttc gattgtatat ttaaactatt aattaagtct atgttcttct ttgctaaatc
    19561 ttctattaat attccatagc ctctttttat atcaattttt atattaaaag tttctaaata
    19621 tttctcaatc atcttcaaat ctttttgtaa agttttatca gatacattta atttatcttt
    19681 aaagtatttt ataggtctat atttattttc gtttagtatc aatttaagaa attcaatttg
    19741 cctcgacaca agcatactta gccctcccta cctatgttta tatatttcta tgtttatatt
    19801 aagtactatt ttaacatatt tactaactat gtaaaattac taagatactt ctgtatcata
    19861 aaagaattta tgatacacct tactaaattg atataataga taatataatt tcaaaataaa
    19921 aattaaggat atttagaaat agttaactga ttctaaatat ccttattatt attctatata
    19981 cttgttgtta ttccattaat tatttttact attatttata atttaagcac caagtaattc
    20041 aacttcacta ttttcactcc ttatagtagg ctttgttacc cctataatca atgctgttat
    20101 tactgtacca atcaatatac aagctatata tgcaactggt gcactacatg caaatggtat
    20161 tacaaatatt cccccatgtg gtgccattaa agttatatct aaactcatac atattgcccc
    20221 acctatacaa gaaccaatta tatttgctgg aatcattctt aatgggtctg cagctgcaaa
    20281 cggtattgcg ccttctgtta tgaaagatgc ccccattata gcagttggta gagatgactt
    20341 tctttcttct ttagtaaact tatttttgaa tattaacata gctaatgata ttgctaatgg
    20401 aggtaccatt cctcctacca ttaatgctgc tgatggttca aatatattac ttgaaaacat
    20461 agccaatcca aaagctgaag ctgttttatt aataggtcct cccatatctg atgccatcat
    20521 ccctgctaat attgcaccta ataatacttt attagttcca gacatacttt gtaaccaaga
    20581 ttgtaaagct tcatttaacc atgatgctgg cgtattaact acaaagaaca ttatagctcc
    20641 actcgtaaat gcaatcaaaa gtggacatat caatacagca tttactcctt ttaatacatc
    20701 tggtaaattt tctgttatct tcattactcc taaagctata tatcctgttg caaaaccagc
    20761 taccatacca cctataaaac ctgaacctcc aataactgcc ataaaaccag ctatcatagc
    20821 aggagcaaat ccttgtcttc ctgctattga tttagctata aaaccagcaa gtatcggtat
    20881 aaataactta aatgctgaat cgcctccaag ttgtccaaag aatccagcta tagggttgta
    20941 tgtttcatga gttgggtctg atgcaaatat accaaacata aaagctatgg ctataccaat
    21001 tccacctatc actacaaatg gaatcatttc agatacacca ctcattaagt gcttataaac
    21061 accctttttc tctgaccctt gaagcatttc ttttgaatct tctaaagtct ttccacctgg
    21121 tttaatttct ttagccattc cattttcagc gtttataatt aaatttttag ctaatgaaac
    21181 attcttagca tctactactt tcttttgtag cactttcttt cctataaatc tactcagttg
    21241 aacttcttta tcacaagcta ttattacgta ttcagctctt tttatatctt ctttagtcaa
    21301 cttattttct acacctatag ctccatgagt ttctatttta acttcatatc caagttcttg
    21361 ccctgcttcc tctaatgctt tttttgccat aaaagtatga gctatacctg ttggacatcc
    21421 tgttatccca actataagac ctttattttg attattacta aaatctcctg attctgcagc
    21481 tttattatta aatatactta atatttcgta tggagtttct gcacttagta gatgcttaag
    21541 aaaattttct tccattagat atgtagctag tttagatata atcttaagat gttcatctga
    21601 acctgattct ggaactgcta tcataaaaaa tgacctaagt ttttgaccat cattatctgt
    21661 aatctctcta tctgttctta aatacatcat tacaggttga tttactacat ttgacttagc
    21721 atgaggtata gctattaaat tacccatatt agttgatgat tctttttcac gtttattaat
    21781 atcagctata aacttttctt tattatttat ataatttcca tggtacaaat gatttgccat
    21841 ataattaatc acatcttttt ttgtttgtaa ttgtttatct agtacaatac aatcgcttcg
    21901 tagtatttta cctatcataa attctcccct ccttttaatt tgttacctca taattaattt
    21961 ttatttttat aaaagcactt taacttatct atagcattga atagattcat tttaaactct
    22021 ataacttctc ttgcagcttt tatacatggt ggatatatag tatctggctc atataagctt
    22081 gggttttgtt ctaatagttc tctgcacttc ttataatatg ccgacttaac atcactcgaa
    22141 atatttattt tacaaactcc tagtttaact gcttgtgcta tttcttcatc tggatttgat
    22201 gaaccaccat gaagaactaa aggtatatct actacttctc ttatttcttt taataaatct
    22261 agtttaagct ctggtttaaa accttttgga tatataccat gtgctgtacc aattgcaata
    22321 gctagtgtgt ctactcctgt tttttcaaca aaatccttag ctaattttga atctgtatat
    22381 attatttcat cagtaccacc ttcacttgat gttcctgttg ttcctattgt tccaagttct
    22441 ccttctacgg acacatttaa tccttttgct atttctacta tttccctaga tatagctaca
    22501 ttctcttcat atggtaaatg tgagccatca atcattactg atgtaaatcc acatcttatt
    22561 gcccttaata tttgttcttt attttcccca tgatctaagt gtattaccat aggtacttta
    22621 ctcttatttg cttcttctat gcaactagct acaaagctat ctcctagaaa acttagctca
    22681 tttgggtgta ttgcaagtat tactggtgca tttttttcgt tagcactctg tactactgct
    22741 ttaagtattt gcccacttcc tatattaaat gctggtacag caaattgatt ttcttgtgcc
    22801 acttttagca tttccttcat gtttattaac atattgtacc tcccgatatt ttaaatttta
    22861 ggttgaattt gcttcttgtt aattttgttg ttgtttatat ttaaataata tcagggtaat
    22921 gaatgtcaga aaataacaat cgttttcctt agtgaaaagg aacttttatt atacactcta
    22981 agttcctttt cactaaataa tttttagaag tctgcatcat agttaattat atttctcatg
    23041 tacatcttct ctttttaagt gttttatgct ttagccttcc tagattttat aataaacaat
    23101 taagatacat taactataaa tttaaagata ctcatgcaat agttaatgct atattagagt
    23161 caaaaaaatt aaaaagatat tagctatttg gccaatacct tttcttggat tccaatagta
    23221 tatacgattt atagaaatct tactcacgat tatctaatgt tttacttcca taaactttac
    23281 ataaaacacc aaagtgacac cctccaaatt catctctagc taataaagtg atttggtttt
    23341 ctaagcacca atttataaat tagcctttgt tatcttatgt aaatcttttt ctatctaatt
    23401 taaaaattat tcctaatgct atatagcata taccaattac taatacacca taagccatag
    23461 atactcctat cttaaattct tgcatattaa ttacaataga aactgaaata gatttattac
    23521 aaacaccata aagcaaggct gacattgtat attatccaat tgtatgaatg aatactaata
    23581 tagctccttt taattaaatg atgctatata aatcatattt atcccaattt ttaatctaac
    23641 ctatttatat gtatattcct ttttaataaa aaaagatatt gactaaatag tcaatatctt
    23701 ttagttgatt taaataccca caattttaat ctaattttta agtgtttcct taacataatc
    23761 ttataaatat taaaatttat ctacctataa aatttctcca ttaaatttta ttacatttta
    23821 tcttaaaaca attataatct gaccttaatc atatattata ttatataaat atttttaaca
    23881 aacttaataa ttaaataact atattttatt atccatctta taaatgttta taaactttcc
    23941 actattcttc ttcaataaat tcaaacaaat tttctactgt agtatcgaat actttagcga
    24001 tatccatagc taacttcaaa gaaggattat atttcccatt ttctaagtgt acaatagtct
    24061 cacgtcttac cccaaccaat ttagcaagtt cattttgcgt cataaggagt ttttctctgt
    24121 attctttaat ttttgttttc atcaatattg ccacttagtt acatatcccc cttttatcaa
    24181 agtatatata caacactaat ttagataaag actgtataaa taaaactgca atgaggatta
    24241 tacctgtatc taggtttgat atatttatat tacttgtata aggtgttgca aagaaaatag
    24301 atattattac tatagaatat atcattattt ttattgcaat cttattaacc tttgatagta
    24361 taaattcaga tgattcatca actaaatcat tatatttttt attataaatt gaataacatc
    24421 caaaaactat taaccaactc aaccctggaa gagaagcagt gcttggacct ttaaaaatat
    24481 acttagtggc taatacagct ataaaaaaat aagttattac aagcaactcc aggataagct
    24541 ttgatcttac accagtttct gatttagaca tataaaatca ctccttaaaa attatattct
    24601 ctatactctt taattttcgt ttttatcaat attatcactt agttgcatat tccctttcta
    24661 tcaaaatgta tatacaaaat taatttagat aaagattgta taaataaaat agctaagaga
    24721 attacaccta tatccaaatt tgatatatcc aaacctcttg tataatttgc tgaaaagaaa
    24781 acagctatta gcaaaataga atataacatt atttttgatg caatatgatc aacctttaat
    24841 aacataagtt ttgacgcctc gtcaactaaa tcattatatt ttttattata catgaagtca
    24901 catgcccaaa aagcgaataa aattataaaa gtaatacaaa gatttccctc tttaaaaata
    24961 aactttttta ataatgagtc tataaaaaaa taggatatca taagtaactc tgaaacaaga
    25021 tttgttttaa caccaagctc tgatttagac atataaaatc accccttaaa agttatatat
    25081 ttataacacc ttatgttata aatatataac ttttccaaat aaattgcaat agaatattga
    25141 aaatattcaa taatatcttc ataaatatat tttataaaag attttataat aaacattaca
    25201 atacagtact aaattagttt atttcatcta tcatctcaat catatcattt actaactatt
    25261 attctaatga gcatataaca ttgaaactta taattataca acctaaatgc ctcccaatgt
    25321 accctcaaaa catcatttcc tgtaactgaa gtataattgg tatattttat cactgaaata
    25381 aaaaaacact agtcaataaa gactagtatt ttcaagtatt ttatcattct ttttttaatt
    25441 attggagacg aatcatcaga ataatgccca taatttatct atatgcaaat tctaaattta
    25501 aaataaagtt tcagataaat ttactattct atgctatgat acaacagaaa aaactgaaat
    25561 ctatgagtgg tagcttcata taatcctagt tcctacagta atcaaaactg aggtttattc
    25621 tatatgtaac taatgataaa ttttattata ggagttatta gatctatttg tgttactata
    25681 agtagtaatt atatatatga taatttttta acacttttct gttggctata tagaaagtgg
    25741 tttagaattt aaatttaaat aaaatttaaa ttcaccaaaa agaaatctat attagaaacc
    25801 actactctat tccaccagat tgtaattttt tgttctttat atcacaatgc tataccatat
    25861 taaattgaaa aataagtttt aaatttattt gttacaattc attaattcaa aaaaatattt
    25921 tgagtcatga gttttgtaaa gatttagcca tgaatttaat gcttctgatt caaaaacatc
    25981 taaaagtttc aatacttgaa acgtaaattc caacggagca attcctgaag ccgtaactaa
    26041 attttcatca ctaactacag attccgtttt ataatatttt tctccagagt aatttggtat
    26101 taccatttta agaaactcta agtcattact tgtatgattt ctaaaatcta atagcccttt
    26161 tttagctagg cctaatgtag ctccacatat ggctgcaact atagaatctt gtcttaaagc
    26221 ttctttaact ttttctaata ttatctcatg attcatagat aaccaagtat ttccccctgg
    26281 caaaattaat aaatccttac tttccatatt aaactcatca actgtaattt caggtaaaac
    26341 ttttaaccca cccattgtta taataggatt tttatcaatt cctacagtaa ttacttttag
    26401 tggctttaat ccttttttaa aatatcttcc tgtatttaat tcagcagtta aatatgccac
    26461 ttcccaatct gacatagtat caaatacata catatatact tttctatttt tcatcttttt
    26521 tactccttat gtaattaatt tatatatcta attataaaat aacttaactg acatattcag
    26581 tcagttaagc tattaaattt gataataatc aattaattct agtaaatctt caattatttt
    26641 cttcctaagg cttagtggtt caattacttg tattgtcttt ctataaggta aaagtatatt
    26701 tggtatgtac ttgcatatta cttcctcttc aagcataaat attattttat taggtgttct
    26761 ttctttcaag tagtgcccta aaaaccaatg ttggcttaaa ctatctaaag aatctatact
    26821 cccttctata actaattgaa ttatattttg ttcatctttt atttcaggta taattccttt
    26881 tataaaaaat tcacttgctg aaaattctgt cggtctgtta aatgtatttg atgtttctat
    26941 gatttcacta atcctatcca ctctgaaact acgaacctca tttctcatat tacaaaatgc
    27001 aactacgtac caattattat tccagtgaac aattccatat ggatttataa ttctatattt
    27061 tgattttact ttacgacctg catgatagtt gatttctaca gatagctcct ttaatatact
    27121 attctccaat tttttaagta ctgattctat agacactttc ccaattggtt ttattacttc
    27181 aagggctctt aagtggtttg ttaaaatatc ttcttgtttt tgatttgaat acatttttaa
    27241 ctttaatatc gatttatcta atgcttcgtc taagaagtat ccttcttttt tagcaaatag
    27301 tgctgcatga agtagagatt tttgctcttc tatatcaaaa aaaagaggtg ctttagtaaa
    27361 attatttaaa aggctatacc caccattatg acctgtatct gaaattatag gtactccact
    27421 cgcagaaagt acatcaatat atcggtacac tgttcttata tttatttcta atttttcagc
    27481 tatctgtttt gctgtaattt ttttgtcaga gtttaacatc cacagtatag acatcatatt
    27541 gtcaatttta gccatgtagt ttcacctctt tctatttgtt atataaagtt attatataac
    27601 tttttgattg attttttaca aaaaaacatt agtaaactgc taataattta tactaagatt
    27661 tatttcaaat atttatagat agtctttttc tatagttaag ttatccatta aattacatag
    27721 tagtatatct attttagttg atatattttc agctacctcc cttgaatatt attacaataa
    27781 gtctaaatct tctttcttcc ataaatatat tatgaggaaa gactatcatc tttaatggtt
    27841 taatagtata aaagatatta atttaaaaaa atctattttt atatcagatg ggtattgttt
    27901 tttataaaac tgaaaaaatc acctaataga atctatgatt ttttaacata acctccataa
    27961 attagttcca attatcactt caaattcaaa tttttatctg aagaatatac aatcatattt
    28021 ccatactcaa cataatattg agtgtttggc ttgtatttac aaattattat tctaacaaaa
    28081 acaactatac atagattaaa atcatcttct aaacataact actaaaattg aattaatgat
    28141 atcaattcca ttaatctctt ttaataaaaa attctctttt ctatatgaaa attatttcaa
    28201 aacttttaag ttaaatacaa aaatgactat aaatagattt ttatttacac aaatctattt
    28261 atagtcacta tagtttatcc aataaaataa taaaataaat atgtacacaa taaatgttat
    28321 ttacgtctta agtatttatt tgttagattt ttaattaaaa aaaacaagct aatgaacatt
    28381 aatgctaaat ctagcattat attgctttga tctcctgttt gtacattttg acctacatta
    28441 ctatctaaac tttcatctgt atctatattt atatctggtt ttccattccc atctgtatct
    28501 atatttatat ccggttttcc atctccatct atatctatat ttatatctgg ttttccatct
    28561 ccatctgtat ctatatttat atctggtttt ccatctccat ctgtgtctat atttatatct
    28621 ggttttccat ctccatctgt gtctatattt atattcggtt ttccatcccc atctgtatct
    28681 atatctggtt tgctatttcc tccattatct gggtctggtt tactatttcc accgttatct
    28741 ggatccggtt tgctatttcc tccattatct ggatctggtt taccattgcc accgttatct
    28801 ggatctggtt tgctatttcc tccgttatct ggatccggtt tgctatttcc tccattacct
    28861 gaatccggtt tgctatttcc tccattacct gaatctggtt tgctatttcc tccattacct
    28921 gaatctggtt tgctatttcc tccattatct ggatctggct tatttagatt tggattacct
    28981 gtatcataac ctcctgagcc agtatctaca tttttatcag gcttccaata atcatctact
    29041 ccatcattat ctgtatctat tgctggacga ttataatctg tatcagggtt tccatctcca
    29101 ttggtatcta tatttttatc aggtttccaa ataccatctc catttccacc ttctgtacta
    29161 ggcttccatt cacctgtatt atcagtatct atgttaatat ctggcttcca atcaccactc
    29221 gtatctatat tgatatctgg ccttccatca ccatcagtgt ctatatttat atccggtatt
    29281 ccatccccat ctacatctac atttgtcata tctaacttta acttcttttc atcctcacta
    29341 ccttcaatgt aatttatatc atctccaata tattttacag taatagtttg ttcagtagta
    29401 aaaatatgat gattgctatc taaaggtctc cattcaatag atgcagtact ataattatga
    29461 ctctcactac ccttattatg agtttttaat tctactggat ctttatattc ctttccatta
    29521 atatagaatt gtacgtaacc tcttggagag gcacaatctg gtccttcttt cttatctggt
    29581 gaaatagtaa catttaatgt aaacgtatct gttggtttaa aaacatcagt tttagcttta
    29641 gactcttcta caactaatga agtttctgta tcagcaggaa taatttctgc cttataatat
    29701 gctctatgcc cccaataagc atccttaaaa ggatatatac tcgaaaactg tgttgatgta
    29761 atgcttaatt gatatttccc agcatcaact tgttttgtaa gatcatcact tcctaaattt
    29821 atatctggtt ccatcgtttc ctcatttaaa cgttgagaac taatagtcat aaatttttta
    29881 tctgtgagtt tttcaccttt aggagtaatt attggaatac caccatcttt aaatatccaa
    29941 tctaaaaatg atttttctac gtcttcttca aatggtaatc catcatatct tttaataatc
    30001 aaatatggtg gagtatcatc aatagtaaat tcttcatatt gctttaaaaa ttgagaacct
    30061 gaacctatat ctttaatata aaaatcatct ggttttagaa cttctccagt aattttatct
    30121 ataacaacta aattaacaga tacttcagat cccttaaatt gatcagagaa ccataagtaa
    30181 agaatccctt gagcatctgt ataactaggt gctccataag gataaatttt tccatcaatt
    30241 agcattttaa aatcatcaac tagtgtagta ctaactttat cttgccctaa atacgttaga
    30301 gatattttat tcataaaaac ttttgttttc ttttctaaat caccgtatgc aactgctcca
    30361 cctaaacttt tgaatgttgt tgcttttaat gaaccacctg ttactataac atctcccgtt
    30421 gtagcactta ggtcaaaaat ccaatctccc actcctgtca tataaggtaa aatcgttcct
    30481 ccagttacaa gtatacgata tcctctattt gttcctggat taacacatcc atccccaaat
    30541 gcactaccat gtgcacctcc atatgaatag gaaagtccac cattaattgt aatattccca
    30601 ctataaccag aacctgtgct aggatctact actgagggac ttaatgcatt ctttgttgtt
    30661 gtatagtatc ctccacctat tccagctcca tggtatgcac ctttagcagt tataatacct
    30721 ccattgattg tgatatctcc accactacca ttaccgcctc cacctattcc agctccatat
    30781 cctgtattac gactcgattc ttgacctata gcagttatag caccaccatt aataataata
    30841 tttcctccac tttcagtatt tccaccacca atacctgcag aataataatt tccaacaact
    30901 tttaaacttc ctctattatt actatctagt agtgtaaggc gatctccttt ttttaacttg
    30961 tctccatttt ctagagttac atctctagga atttttccac cctcaggaac tataaactct
    31021 ccttcaatat ctctatttac aacagaatca tcaataatta gagtagtacc ttttcctgct
    31081 ctcatacctg gataatatac atcacctgac tctagcttgt tttcactacc atcttgtaat
    31141 ataacatgtg catatgcacc accatcttta tctggtgtta aagtaaatgg gctattagat
    31201 gcagttttaa tatttactcc atcaaatatt aattcagctt ttacatcttt aggtataaca
    31261 atcctatgtg ttgttggagt atttggattg ttattttgaa ttgtcatttg ttttccacta
    31321 agaatagtta aaacgccact tgcaaattta aaatcgacat ttatttctcc accactaatt
    31381 ttaaagtctc ctacagacgt aggctcttct gcagtggctt cttcttctac aactactgca
    31441 ttagcatctc cttctgcatc tcctgcatta gtatctcctt ctgcatctcc tgcattagta
    31501 tctccttctg catttcctgc attagtatct ccttctgcat ctcctgcatt agtatctcct
    31561 tctgcatttc ctgcattagt atctccttct gcatctcctg cattagtatc tccttctgca
    31621 tctcctgcat tagtatctcc ttctgcatct cctgcattag tatctccttc tgcatttcct
    31681 gcattagtac ctccttctgc atttcctgca ttagtacttt cttctatagt atctgcgaaa
    31741 gtatttgacg cattaaatga tgctactggt ccaagtccca ttgagatact taaaatcatt
    31801 gatagtgctt tctttttaca tttttgttgc ataaactccc cctcccctta ataattttta
    31861 atatacactg tatacatcct tatatacact ctaataattc ttaatatacg ctgtatacat
    31921 tctaatgcac actctaataa tttttaatat atacttaaaa cttatatttg tcaatgaata
    31981 tactgttttt tcaaccttat atattataag tattcattat ttgctaaata actacaataa
    32041 aaattttaat tatataaaat ttatttaatt ttttatataa taatactaag gggtaattaa
    32101 ttgaaaaaac tagtaaaaat attaataaat attatttgca ttattacgct aattttctct
    32161 agcctttcga tttacataaa attatctgaa tataaaaaag ctgatgaagt atatacggaa
    32221 ctcagagaaa acactatcaa taatagcaaa catcaagaac tttatgataa aaataatgat
    32281 tatagattct ggcttaaaat aaacaacgta aatatagact atcctgtagt acaaggatat
    32341 aacaatgatt tctacctaac tcatgatttt tataaaaatt atcttccttt aggtagtatt
    32401 ttcatggatt atagaaataa ttttgaaaat gataagagtt taatagtcta tggtcattat
    32461 atgaaaaata aaactatgtt tggtcagcta gaaaactata ctgatgaagc atttttcaaa
    32521 gaaaataact tagtagaaat aaattataaa gtacaaactt atacttatga aattttttca
    32581 gtatatactg ctgacttaat taacagagat tatttaagta tacactttaa tagtaattat
    32641 gagtttaaag attatttgaa ttatataacc taaaaatcag tacacaaatc tgatataaag
    32701 gtagatattt cagataaaat tataactttg tatacttgta actatgaatt taaagatgct
    32761 cgtactatag ttcatgctaa attaatttca aaaaaagaga ctgataagta ggtttgtgta
    32821 aatgcagact tacctacagt cttttttgaa cgtaaaatta gtaagtatgg aataatattc
    32881 atattaaact tttgtaggca aagaaatgaa aaatcaaaga gaaataatta ttacagattt
    32941 agattaccaa gctgaattaa gaaagtgtaa aactatggag gatgtagttg gtgaagatag
    33001 tatataatag tttaacttat aaattatctt ggtgatatta atgaagtttc aaagtatata
    33061 ttatttattg atataaataa tattaaatct gttgctaaca gatgtacctt tgtttggaga
    33121 caaactattt aagaaatata actaaaatgt tgaagtagct acctgacttt attttgaaat
    33181 gcgaacaaga ttttggcatt aagataattt agaaagaatc actggtacac aaggatgtga
    33241 acttagaatg aatagaagta ttcaggcata aggagctttc acccaaataa aacatagtat
    33301 gaactttaaa agaattctaa tcagaggcaa tcaaaatgtt ctttcatagt ttatacctgt
    33361 agtgttagac atagtattta taagtttcac aaataagata atcattaata aatgtagtat
    33421 gtatattcat cctctcaaaa atatttttta atcttacact ttgtaaatta ttctatttta
    33481 aaatggtatt tttatacctt tatttcttat gaccgttttc aagctcaaat tttgcataaa
    33541 tataaattaa tgaaaagcaa gtaaaaaaag aactgtcgca cagcaattta aaattactca
    33601 ttcgacagtc cttatttcgt ggatttaaat agtggagaag aatcacaaga ataataccca
    33661 cgattaaacc tttatacaat acattttata tgactttacc atcactaata gttattatac
    33721 aatcagccat cttagctatt tcatcattat gagttatcat aaccaacgtc tgcttgtatt
    33781 catttacaca atactttagt aaattcatca cctcattagt tgttttactg tctaaatttc
    33841 cagtaggttc atctgcaaaa attattgatg gcttattggc aagtgatctt gctattgcaa
    33901 ctctttgttg ttgaccacct gataattcat taggaaattt attaatctga ctttctaatc
    33961 ctaacttagt tattaaatca ttaatataat tattatctat ctttccttta gcaattaaaa
    34021 taggaagaac tatattatca taaacattga taacaggtat tagattatag ttttggaata
    34081 taaacccaaa ttctttactt ctaagattag atagcttttc atcacttaaa gtatataaat
    34141 ctaaattatc cataaataca ttacctaaag ttggtttatc aagccctgcc atacagtgaa
    34201 gtaatgtgct ttttccagaa ccactttgtc caattattgc actaaattta tggggttcta
    34261 tctctaaagt aattccatca acagccttta tttcattttc tccttttcca tatatttttt
    34321 taatatctat aacttttaac atcttcatac atttacctcc caaattattc attctctttt
    34381 ataccttcaa taatattcat actttcaaaa tctctattac ttacaactac tgatattaaa
    34441 catacaaata cagatatagc aaagaatagt aaagattcct taattgggaa tgtaaaagac
    34501 ataaaattct ctattccata gtttatatac gcatcattat tccaatttgt aaatttaact
    34561 agatttataa atgatggaat catagctatt ataaagctaa aaactgcata tgctaatgct
    34621 tcatatataa gcattttttt catattttta agactaacac ctaatgctct aagcgttgaa
    34681 atttcttttt ttctaattag tagatttgtt cttatagtac agaaaatatt aattgatgct
    34741 attattaaaa ctagtgcaat tattgctatt tgtgatttaa tgtaactttt atatatactt
    34801 tctgacattt catgataact taatctacta ttaaatagag accctggtat acttcttgaa
    34861 attttctgta tctcattatt aacaatctca tcatatggat tttctaaatt tatgcctaat
    34921 tgagtgtatt tttgttctcc tgttatgttt ttagagtgaa tattacttgt tataatttct
    34981 agatctggca taaaatcgcc atctcccata gcaatccatt catcctttaa aattacagcc
    35041 actcttacct tcatctcttt ataaacaatt gtattatttt cttcaacagg aatttttaca
    35101 gttattatgt ctcctatatt taattctttg aatataggct ttatagtatg atcatcaact
    35161 atatcataaa aataattata tactgctaca tttggatatc catcagtgtc ctttttaata
    35221 tcatctaagc taccttcttc aacaaagtca tttaactttt catctatata atcatcatca
    35281 taaagcttta aaactaattt atcttccatt atctcttttt tttctactcc attataggtt
    35341 gtaaattctt tgtttatatc cttattatta aaagtaaaca ttccatttgt tatttgaatt
    35401 ttatgtatac ttttaacacc cttaattttt tctatattct ctacatcact atctgtgtat
    35461 tttgatattt gcgggtctgc atttactcca aattgcattg ttatattata tctattttgc
    35521 atatcttcaa ttttactgtt gacctcttct tgcatacttg agaatgtagt aatgaatata
    35581 tatcctccta aagcaataga caacatagat atagcagctc taaccttatt tcttccgata
    35641 tttttaagtc ccataaatcc ataaaatcca aatattttgc ttactagtct gtctattcca
    35701 agtctacttc tgtgattttt aattttgtct gtatttatta ttgattcaat aggtgatatc
    35761 ttgccgattt taaaagttgg tataatacaa gatataaaaa cagaaatcat tccaaccaat
    35821 atagctttta taactatttc attatttata tataatttag ggttaagacc agcttcactg
    35881 tataaaactt cgttataatt actaattcct atatatgaat atgtaacccc agctactaac
    35941 ccaagtagta tacctattat tgttataatt aatgcttgat agattatcat acaccttatg
    36001 tttcttttct ttgcgcccat cagtctaagc agtcccattt cttttactga ttgatttagt
    36061 gtaatattga aaatattaaa tatgaaaatt atagatactg tagttattaa aacatttctt
    36121 ttaaaaacat tcggatcatt cttatcatct tctacataac gaagttccct tacaagaggt
    36181 acatttggta gaaaactttt ttgtcccaac ttatattttt tcataagata atcacattca
    36241 ccttcaatat ttctccatcc acttttaaaa cttaatatac tattataact aatcgcatca
    36301 tgaggtataa tgttatttgt ttcatcattg ccataagtta ctgcttcgta ttgccaaacc
    36361 acatcatagt acccttttgg tttttccata actcctacta ttttaaattc tttatttata
    36421 gaaaataatt gattacttcc gttagtatct ttatagttct tttttattgt taaatttaat
    36481 gtagatccta ctccttcact taaattcatt gcttctagtg cttttttctc taatactatt
    36541 tcattgttgt ttttaggtag tctaccttct attattttgt tgtatctact ttttagatac
    36601 tcttcgtttg atgaagttaa tataaatgag tttccttttt tatctgaaat acgtcctaga
    36661 ttttgtaccg aattaccctt tgatactttt tcatcagttt ctaatttttt agcatcatca
    36721 agtgtcaaat cactaaactc tacatggtat ccactgtaaa gttcatgtat tgctactaca
    36781 ttgttttcat tttgtgaatc ttttataaca ctaggtccaa atatcaacat aacacctaac
    36841 ataactccta ttattaaaag taatgttcta agtttatttt tctttaaata tgctagtgac
    36901 atttttaagt aaatccccat ataatcctcc tattttacta taaattattt atccaactca
    36961 tctgttaagt agattggtgg atattttaaa tcttttaatt cttcattatt ttttgaagct
    37021 tactaccatc ttcctcatga taaacttgca gtatcacctt atttacatgt agtgcataat
    37081 aatcaccatt ataaaaatat tagtatttat aacctggata atttttgtaa aatgatttat
    37141 aaagtatccc atcctaattc tattttgtat acttttcttt tgtaatacgc tctatatcat
    37201 cacctgaaac tccttgatat gtcatatatt tatctatata tttttcagct tcattccatt
    37261 ttctaaaata gttgttgtat ataataaatc ctattatggc tataatgctt ataattaaag
    37321 ttaataaaat agctttgtat tttctcatag tgaatcttcc tacttcaatt taaattcttt
    37381 aataagtttt aattctaaag acttagtttt atcatcaaat ttcttaactt gaatttttat
    37441 atctcccaaa ttatcaacct ctacatttac ttcaccttta tcaaatactt cttcaatttt
    37501 tctaaaaaat tctttctcac ttatttctat atgaatcaat gatctatatg ttataaatgg
    37561 ccattatgaa tttatcatct tctgacagct tttcattata agaaaaatct ttaacacatt
    37621 gaattgataa tatttccttc gtatccttct tttccttagt tattgaataa tgtaaaactt
    37681 ggctaggttg ttcttttgta tactccaagt ttcccaaaga caaaacaaaa cttccatctg
    37741 atttattttc agctacccta agaccactat tttctattga ttctgatatt ttctttgaca
    37801 agtcttcttg atactagaaa tctgttcaat agtatatatt ttttcatttg tacctgaaac
    37861 cttatttgtg catcctgtta ttaaacctag tgttaagctt atagctataa ccatagttat
    37921 tgtaattttt ttatcttcat ataatcctcc ttatatattg aaaactcgtt atttctcata
    37981 aaaaaaagac gctatctttt tctattaaaa gataacatcc ctatatgttt agtatcaata
    38041 tatgttcccc aactggtagg ttaatcgacc caactatcaa aattttgatt taatggtata
    38101 taaatattca atataaattt gtctttttta tcttcaaatg ataaatctcc tctatatttt
    38161 tttatagaag atttgatgct ttaaatccct attccatgta caagtttatc ttttttatct
    38221 gttaataata aacttttatt ctttctaatt gaatttattt tactattctc acatttaatt
    38281 acgaaatagg actttgagat agttcctttt atttgtatat atttatcaat acttttatca
    38341 tgtatcttat cgcaagcttc tattgcatta tctaagtatt tgcaaatata ttagatacat
    38401 ctattggttt tataaaattc actttggaaa aattgatatc acaaatgaat ttaatttttc
    38461 ttttttcact tacatcactt ttttcattta ttattatatc caatataaca ttacctgtat
    38521 tgtaaattga tttaaattct ttaatttaat cttttaaact atttacatac ccatcaattt
    38581 tcctttttta tatttgagat tttctataca atatatatga ttatttatat catgataaag
    38641 cttcttaact ttagcgtgtg attcttgaat acttagataa tgagaatact gcatatctaa
    38701 cttatttttt attacttcat tttgcaattt taacttattt tccttaatta tttttataaa
    38761 cactataata atgactaagc tactagctag tattaacc
//
LOCUS       DAEHWO010000035        36656 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEHWO010000035 DAEHWO010000000
VERSION     DAEHWO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36656
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.035"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            260..637
                     /locus_tag="KNP54_002080"
     CDS             260..637
                     /locus_tag="KNP54_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0892980.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            630..1778
                     /locus_tag="KNP54_002081"
     CDS             630..1778
                     /locus_tag="KNP54_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBF0892981.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            1795..2397
                     /locus_tag="KNP54_002082"
     CDS             1795..2397
                     /locus_tag="KNP54_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBF0892982.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(2490..3512)
                     /locus_tag="KNP54_002083"
     CDS             complement(2490..3512)
                     /locus_tag="KNP54_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBF0892983.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(3841..4023)
                     /locus_tag="KNP54_002084"
     CDS             complement(3841..4023)
                     /locus_tag="KNP54_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892984.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4336..4755
                     /locus_tag="KNP54_002085"
     CDS             4336..4755
                     /locus_tag="KNP54_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBF0892985.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            4886..6727
                     /locus_tag="KNP54_002086"
     CDS             4886..6727
                     /locus_tag="KNP54_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0892986.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            6754..8641
                     /locus_tag="KNP54_002087"
                     /pseudo
     CDS             6754..8641
                     /locus_tag="KNP54_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
     gene            8649..10649
                     /locus_tag="KNP54_002088"
     CDS             8649..10649
                     /locus_tag="KNP54_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0892987.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            10911..12170
                     /locus_tag="KNP54_002089"
     CDS             10911..12170
                     /locus_tag="KNP54_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBF0892988.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            12231..14018
                     /gene="iorA"
                     /locus_tag="KNP54_002090"
     CDS             12231..14018
                     /gene="iorA"
                     /locus_tag="KNP54_002090"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBF0892989.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            14020..14595
                     /locus_tag="KNP54_002091"
     CDS             14020..14595
                     /locus_tag="KNP54_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBF0892990.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            14648..15718
                     /gene="buk"
                     /locus_tag="KNP54_002092"
     CDS             14648..15718
                     /gene="buk"
                     /locus_tag="KNP54_002092"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBF0892991.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            15936..16637
                     /locus_tag="KNP54_002093"
     CDS             15936..16637
                     /locus_tag="KNP54_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892992.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            16697..17203
                     /locus_tag="KNP54_002094"
     CDS             16697..17203
                     /locus_tag="KNP54_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBF0892993.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            17378..18400
                     /locus_tag="KNP54_002095"
     CDS             17378..18400
                     /locus_tag="KNP54_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBF0892994.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(18547..18855)
                     /locus_tag="KNP54_002096"
     CDS             complement(18547..18855)
                     /locus_tag="KNP54_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBF0892995.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(18915..19343)
                     /locus_tag="KNP54_002097"
     CDS             complement(18915..19343)
                     /locus_tag="KNP54_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0892996.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(19566..21023)
                     /locus_tag="KNP54_002098"
     CDS             complement(19566..21023)
                     /locus_tag="KNP54_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBF0892997.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            21441..22355
                     /gene="nadA"
                     /locus_tag="KNP54_002099"
     CDS             21441..22355
                     /gene="nadA"
                     /locus_tag="KNP54_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBF0892998.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            22368..23669
                     /locus_tag="KNP54_002100"
     CDS             22368..23669
                     /locus_tag="KNP54_002100"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBF0892999.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            23650..24486
                     /gene="nadC"
                     /locus_tag="KNP54_002101"
     CDS             23650..24486
                     /gene="nadC"
                     /locus_tag="KNP54_002101"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBF0893000.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            24742..25074
                     /locus_tag="KNP54_002102"
     CDS             24742..25074
                     /locus_tag="KNP54_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBF0893001.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            25236..25421
                     /locus_tag="KNP54_002103"
     CDS             25236..25421
                     /locus_tag="KNP54_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893002.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            25448..26533
                     /locus_tag="KNP54_002104"
     CDS             25448..26533
                     /locus_tag="KNP54_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBF0893003.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            26526..26984
                     /locus_tag="KNP54_002105"
     CDS             26526..26984
                     /locus_tag="KNP54_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893004.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            27019..28110
                     /locus_tag="KNP54_002106"
     CDS             27019..28110
                     /locus_tag="KNP54_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0893005.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            28115..28339
                     /locus_tag="KNP54_002107"
     CDS             28115..28339
                     /locus_tag="KNP54_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893006.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            28349..28912
                     /locus_tag="KNP54_002108"
     CDS             28349..28912
                     /locus_tag="KNP54_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893007.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYNKSVDALKNKATFKKVLK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            28873..29502
                     /locus_tag="KNP54_002109"
     CDS             28873..29502
                     /locus_tag="KNP54_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893008.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            29542..29679
                     /locus_tag="KNP54_002110"
     CDS             29542..29679
                     /locus_tag="KNP54_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0893009.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            29679..30431
                     /locus_tag="KNP54_002111"
     CDS             29679..30431
                     /locus_tag="KNP54_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893010.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            30444..30929
                     /locus_tag="KNP54_002112"
     CDS             30444..30929
                     /locus_tag="KNP54_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893011.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            30936..31085
                     /locus_tag="KNP54_002113"
     CDS             30936..31085
                     /locus_tag="KNP54_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893012.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(31221..32042)
                     /gene="yidA"
                     /locus_tag="KNP54_002114"
     CDS             complement(31221..32042)
                     /gene="yidA"
                     /locus_tag="KNP54_002114"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBF0893013.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            32535..34229
                     /locus_tag="KNP54_002115"
     CDS             32535..34229
                     /locus_tag="KNP54_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBF0893014.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYIRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      34561..34671
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            34775..35146
                     /locus_tag="KNP54_002116"
     CDS             34775..35146
                     /locus_tag="KNP54_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBF0893015.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            35241..36188
                     /gene="trxB"
                     /locus_tag="KNP54_002117"
     CDS             35241..36188
                     /gene="trxB"
                     /locus_tag="KNP54_002117"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBF0893016.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            36292..36609
                     /locus_tag="KNP54_002118"
     CDS             36292..36609
                     /locus_tag="KNP54_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBF0893017.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
BASE COUNT        14502 a         3859 c         6339 g        11956 t
ORIGIN      
        1 tataatattc cttgtgtgaa aatataggaa tttttattaa atagttttaa tgtgtaaata
       61 acattctaca ctattgtaat taaatatgta aaaagtaaaa tatttaaata gatatatttt
      121 aaaatctaac ttttaatatt gtaaaaaaat tagaaattta acaaaaagta caaaaattca
      181 catttttttc ataaagtgtt tgactaaaaa attcacatgt tgtagaatta aggtagcagg
      241 agttttgagg gaggtgtaaa taatgataag aaaaatacca caagcagaac taaaagtaat
      301 gaaattcatt tggaaagtag atgttacagt gacatcaaaa gatgttattg aagctatgga
      361 acaaaaatat ggctggaaac aaaccaccac actgacactt ttatctaggc tggtaaaaag
      421 aggattctta gatgctcaaa aaatagacag atatacacat tacacaataa gagtaaaaca
      481 caaagattat ttaagttttg agacaaagga tttcctaagt aatatacatg atgactcttt
      541 aagaagctta atttcagcat tacatgatga tgaaaatata ggtaaagata agctagattt
      601 tctagaaagt tattttgata atttaaagga tgaataatta tatgctatat gtttttgaaa
      661 atcttataaa gacaactatt gtatgtagtc ttggtatttg tctattatta tttttgaaaa
      721 gatatttatt taagaagttt agtaagagat tcaattatta tatttggttg ataatagtct
      781 ttagaatgtt actttttcta tttaattata caatagtgta tgaagtaaaa gaacccaaag
      841 aaaatgcatt aggaaataat attacacaaa ttgatatttc tacagataat aatcttatgc
      901 tgtatgtagc ttatttatgg ttatttgtaa ctatagtcat tgcagtttat acatttataa
      961 agtatacaag atttaaaaat ctagttgttg atgtatctta tgatattgaa gataatgata
     1021 taaactgtat ctacaaaaac ttgttaaaag aattaaatat aaaaaagaaa attgaattaa
     1081 gaggttctga tgaattgata agtccagcag gtatgggatt atttaaatct tacatattct
     1141 taccagacta tccttatagt aaagatgaac taacttggat tttgaaacat gaattaatgc
     1201 attttaaaaa taaagatatt ttaataaagt ttttagtttt gtctgttaga ataatatatt
     1261 ggtttaatcc acttgtatat gtaatgagca ataaagtaaa tctagattgt gaattatgtt
     1321 gtgatgaaag tgttttggta gaatgttctt taaaagataa aaaagaatat gcactagcac
     1381 ttataaagtc aattaagttt agtaaaaatt ataatagtaa gattttgaca accgagtttg
     1441 ataagacaaa tttggaaaag agacttgaga gtattgttaa aaagaaaggc aaaagtggaa
     1501 tactaattgc tgttttagta tttatgactt ctataacatc ttttgttgaa gttgatgctc
     1561 aagttagaat tgatgagggt aataatggaa tgaataacaa tattaatgaa tttttattga
     1621 ataagacgac tgataaaatt ataaatattt attataaaga tgcaccaaat gaaattagga
     1681 aattttatga agataaatgc gaattagaag gtaaaatacc tagagactat gacataatag
     1741 aaatggatat gaaagattat aatcaattaa taaaataatt ataaggagga ttttatgtta
     1801 acaaaattaa gaaaaatagt agctattatg tgttgcttat tgcttacttt tacaagtgtg
     1861 gcatttgctg acacaagtaa agagaaagga ggaagtaaag agactgttcc agagaaaaac
     1921 ctagattctt ttactctttc tgggtatata tatacatatg aaaatgcgcc acaagaaata
     1981 agagatgaac ataaacaaaa ttgtgaagag ataaatatag accctaagcc agatgatgag
     2041 atatttgttc cagaatcagc taatctaatg aatgaggaca atagtaaagg tgtttatgca
     2101 agttatactg tttcttataa tataggtgct aaaactataa caattatgag taatgagtat
     2161 ttgactataa gtacaacaaa agttatacga aagggtaata gcggaaaaga agtaaaagct
     2221 gcacaaatca tgttaacttt acttggttat aatgtaggta tagatagttc ttttggaagt
     2281 aagacatata atgcagttgt aagtttccaa aaaaaatacg gtttgtctgc agatggaata
     2341 attggtccag ctacttggga taaattgggt agactaactg accctactct ttcataggat
     2401 taaaatctaa aaatatatta aatagtgtct caatatgatt tttcaattta aatgagacac
     2461 tatttaaata taaatgttat aaaactattt tacaataaat tccatataac tctaccatct
     2521 atatccttaa cattttgaca accagtcaaa atcatagtct cacataactc attcctaacc
     2581 ttctctataa aaaactccac accatcaaga ccaccgccaa aagaagcagt aacaaaaggt
     2641 cttcccatca aaacagcatc agcacccaat ccaagcatct taactacatc aacaccagtc
     2701 ctaactccac catcaacaag tattgttatc tttcccttta cagacttagc tatatctgga
     2761 agtacctcac aagtaccagg agtataatca agtactcttc caccatgatt tgaaacaata
     2821 atggcactag caccagactc tacagccatc aaagcatcat ctacagtcat aattcctttt
     2881 ataataaaag gtaatctagt ggattcaacc aattctctaa tctcatcaat tgttttagga
     2941 gaaaaaggat tttcttgaaa ttgattatta ataagtccac aagcatcaag gtctacacca
     3001 actgcaaaag cacctgcttc ttcagacaat ctaattttat ctattatctt tgaattattc
     3061 caaggcttta taaatacaat tccatttccc ctattatcct tcaatacatc taaattatcc
     3121 agtaaaaaag tatctacatt agtatcgcca accatagcat aaattccaga attagaacaa
     3181 cctctaacaa caggctctat gtattctttt tcggaaactt taccacccat gttcaatata
     3241 gtacctgata caggtgcagc gaatatagga gaactcattt ttctaccaaa taattctatg
     3301 gatgtatctg gctttgaaac attatgtatg actctcatat ttatctttat tttttctaga
     3361 ctttttctat tttcaatgaa agacgaacca cttcctttac cacccatacc aggaacatct
     3421 ccagcacaag ctaatccatt acaaatttta catactttac atgttccatt aaagttctct
     3481 ctagctgatt ttagtaagtc attgtaatcc atacaaaatc tctccttttt ataatattaa
     3541 aattgagtat tactatattg aaaatatctt aattgtaaat atagggatgt tattatgatg
     3601 agctaaacta gataatacat attagatatt ttttattgtt gtagatagtt aaattatatc
     3661 atattagata gtcaaatttt gaaaaaaact aacttattta agtatacatt ttgaaaaaat
     3721 taaaaaagct atatatagat ttttaaagaa atctatatat agcttttaag tttatgtcaa
     3781 tcttttttgt taatgaataa ataatataga atacaatata caaaaaagtt tcttgaaatg
     3841 ctaagataat ccccatttac aaagcaacat cattatactg tgtaaatttg aatcaacaat
     3901 gttttcacca tatttcatca taaaatcctc taattgtgtg tcaataaatg aataatatcc
     3961 acttatacta tcgatgtatg cagtcattaa gtgtatacat tcatcacttt tatctttata
     4021 catatatatc tccccctata tacaatatat aaatttagat accaaatcgt atcatattaa
     4081 atagttaagt gtgtaacatc tatgcagtta tatatttata tcattatatt aataactaaa
     4141 gtgagttttg acaatagatt ttgggaaact ggatgttcaa agtgcaaact tggattttaa
     4201 aatcattaat taagatagcg cataggaata tatgtataca taacttaatt ataaagatta
     4261 taaacaatta cttttattaa ctttatttaa atggtagaat aacttggaga ttaataatta
     4321 taaggaggat ataatatgag tttatataag tttatatatg atgataagga atatttatta
     4381 aaagaggaga actgtagtgc tttaataaat gatgaagaaa atccagttca aggagtaagt
     4441 atttcaaaaa taattgatat acttaatgaa gcagaagaag ttgattttga tgtagaatat
     4501 tatcaagaag catgtccatt atgtttagaa ggagtaaaag aaaagaaaaa attctttcct
     4561 tttttagaat atcactttta tattttcagt aaagatggag aatatgtaat aagcaatata
     4621 tctgttgatt ataaaggact atcttttaat aaactatcaa gggcaaataa agttgataat
     4681 agttatattg taagtgtgat aatttgcgaa aattgtcagg attatatagt tcagatagaa
     4741 aattgtatag tttagtgtaa agtatgtctt aatttaagag aaatttctaa attgagacat
     4801 caactttttt caaaaatagt atggaaaatt actaaattta tgagataatg taagtcggag
     4861 gtgagttaca atatatagta aatatttgga agagatagat gatacaattt tagattcaat
     4921 gtttaaacta accttgaatg aaagattatt gactaataac gattttattg aaaataaaat
     4981 tgatgtagta aagaatttaa ttgattgcta taaaactgaa caaaatagtt taatgttatt
     5041 aaaatcaaat tttttgctag ctttattata tggtattcaa gggtttagtg aaaaaatgaa
     5101 agagtatatt ttgatttcct gtaaatatat tgataaatgc ttacccaaag attataaatt
     5161 tttagcacga ttttattcac aaatagctat tttaagttta aaaaatgaag atgtaaataa
     5221 ggcaaattta tatatggata aatttaatct tatttgtgat gaaaataatt ttctaattga
     5281 agaaattatt tttaaatcac aacttattta cattaaggca agtaagtgta tagaatcttc
     5341 tgtaataatt aaagaaatag aaacgttgta tataaagata aaagaaatta acgattttaa
     5401 ttgtaaaaaa atatattttt ttattattgg taaaatatat tttttgtttt tggatgatgc
     5461 tctaattgct aaggtaaatt ttttaaaagc aagaaaatat gcagatttac taaaggatat
     5521 gcaagtatct tcactatgta atataaagat aggtgagtgt gaatgttcgt ttgaaaatta
     5581 tgaatgttcc atggaatatt tcaatgaagt aataagcaat aaaaagtata gaaatgtaaa
     5641 tataattcaa aaatatagag catcaaacaa cataactaaa atattaataa agactagaaa
     5701 ttatcctgtc gcaataaata atttagcaaa atctgaagta tatctagaaa aaattaaaaa
     5761 tcatagctta aaagaagtag agaagtttga tttatttata agtttagcca tgtattatgc
     5821 aaaaagtaat gaaaaatctt ttgaacaatc aatatgctat ttagatagag ctaaaaacat
     5881 attaaatatg ataaaaaata tagaagaata tataatatat gatttagaaa taatttatca
     5941 ccaggcaaag atatattata tctttggata ttatgacaat gccttaaata caaataaaaa
     6001 actccttgaa aaatctaaaa atgctaaaaa ttataattat gtgaagttag catacaagag
     6061 tatatatttg tgttttgaaa agattcaaaa ttatgaaatg agtatgaaat actttaaaat
     6121 gtattatgag ttaaaaatga tgtatataaa agctcgaaat agaaattata tagattcctt
     6181 aaattataga catgagtata tagaaaaaga aataaataac atgagaaaag taaaacttga
     6241 tttagataaa aaaaagtatg ttgaccattt gacaagtgca tataatagaa cttttttgaa
     6301 cgatttttta gaaaaacaag aagttagtga atattgcaca gcatttatga tagatgtaga
     6361 ttactttaaa gaatacaatg atacttatgg acattataat ggagatattg ctcttaaaaa
     6421 tataactata ataataaaaa aatatctaaa aaaagacatg cttatgataa ggtatggtgg
     6481 agaagaattt ctgatattat ctgtatgtaa agattataaa aaaagtaaaa tatttggaag
     6541 aaaattatgt aggattgtaa agaaattttt aaataataat ttgacagtta gtattggcat
     6601 tgatacatgt aaaaatagta gtatagatat aaaagaaata attgaaaatg ctgataaagc
     6661 tttatataaa gcaaaggaaa gtggtagaaa tagatgtttg cattatcatg attttaagaa
     6721 tttttaactg ttgaaatagg attggtgatt tacttgaaaa ggagtttaat agaagattta
     6781 aagagaaata taaacaagat agaatacgat atgttgacta aattctatct aaatttgaca
     6841 gatttaaact acatcttgga ttatcacaaa gaccttttaa atacaaaatt agaagataat
     6901 agtagagtct atactttata tttaattagt cttataaact atataaaaaa agatagagaa
     6961 gcatcataca actatttgat agagtcatta aagtatatta aaaaattgtc attaaaagat
     7021 gattcagata taatatctaa aatttatatt tatcttactt tatcagctat ttctataaga
     7081 aaatatgata aggtaaataa tttttatttc tcagcaaaaa aaattataag gcaaaatcat
     7141 ttaaatgagt tgttggtatt gttaaatatg agtttatgtg tggaaataag tgctttatat
     7201 cagaccaaaa cggatgtaat agctttagta gaagaagtgt ctttttttaa aactttaaaa
     7261 aataaagctc ttgtaagtag ggcaaattat atatttggga gagtttatct atatttattt
     7321 aataacttta taaaaagtat ggaatactta attgaatgtc taaaattggc tcaagaaaat
     7381 aatttatact ctatagaggc tttttgtaaa tgtataataa gtttgtgtta tttagagagt
     7441 ggaaataatg tagaagctat aaaatacata aataatgtat tagatgttgc acacagtaat
     7501 aactcaatat cagtaactga aagagtgtct ataaaaatag accttatatg ggcatattta
     7561 aaagaagata tgaataaaga agcagaagtt attttattaa agactataaa attaatgaaa
     7621 gttgttgaag gtgtatataa ggattattta tattcattta tatttttata ttcagctgaa
     7681 attgagttaa agaaagataa ttgtagtttt gaaaaggtaa acacctattt aattttatca
     7741 aaaaatatat ataaaagttt tggagatgtt tttatatata attctaaact agattacata
     7801 tataagttgt atggagattt atatataaaa tttggtaata tagatgaagg tataagttgt
     7861 tatataaaag gtttaaattt agttaaaaag agttcattga atcttagaaa aatatctata
     7921 tttatatggg ctaatagcaa atggatatga gctaaaaaaa gattttaaac tggcaataga
     7981 atattataaa agtatggatt ggtattctga taggtgggaa aaaaataatt cctataaaac
     8041 atctcaagca attcacaaac aatatgaact cagacaaaaa caagagagtt taagattact
     8101 agtggatgat aataagaaat tagaaaatga tattttaaaa gatggactta ctaaactata
     8161 taatagaaga tatttggaac agcagttgga tttatttaat ggaaccagag acaaaaatat
     8221 ggtcgcaata ctggtcgata tagattgttt taaaagttat aatgataatt atggtcatct
     8281 agcaggggat aaagttatag ttaaggtaac tgatattata agaagtgtat ttatagatat
     8341 taccgaacac ataatcagat atgggggaga agaaatttta atattagtag attctataga
     8401 atcaatcggt gttgaagaga ttgataatat agaattatat attaaaagag ttttcaaact
     8461 tcttgaattt gagggtattg aacatatata ttctaaaata aaaaactata taactataag
     8521 tgctggagta agtataaaaa ggtgtcgtag tagaaaagat gttgaaatat taattgaaga
     8581 tgcagataag aacctatata aatcaaaaaa agcaggtaga aatcaataca ttataattta
     8641 aaattgaggt gattttgttg cgaaaaaaaa taggaattat agcctctgat attgaattaa
     8701 aagaaagaat agaagaatta tatagagaag atgtagaaaa tggaactata ataatcgaca
     8761 tacttaacct agacttaatg gaaaatcaag gtcgtatact tgttgaaaaa ggtgcccaag
     8821 ctataattgg tagaggtgga ggttatagct tagtaataga tacagtaaat gtacctgtta
     8881 taccaatgaa tatgaagtca actgaccttt taagagcaat agaaatagca aagaaatatt
     8941 ctaaaaaagt agtattgatt cttggagaca atgaagtttc ttttgactat gttggctgga
     9001 gaaatgtcat aagtactgaa ataactgaag aatggtttga atctaagtat gagataagaa
     9061 gtaaagttgt aaaatatata gaccaaaaag atgaagttgt aatcgtagga ggaggtttgg
     9121 catgttcttt tgcaaggcaa tatggaattg atagtgtatt tgcaactgct agtgatgaat
     9181 ctataagaga agctgtagaa tattgtaaaa aattattaga tacattaggt gaagaaaagt
     9241 ttaataatga agtgttacga aatatacttg atggtataaa agatggagta attgctatag
     9301 atagtaatgg cagtataatt ttgtacaatg aaagtgcaaa aaacatgctt aaagtagaga
     9361 gaaaatgtgc acttaataaa tacatcttag atgtatttcc taaaatggag tggatgttag
     9421 attgtttaca tgaaaaagag gacgtagaag atagaaagat aagaaatata aataatctaa
     9481 ttgttaatac taggacaaca ttgataaaag ttgataatag tacttatgga gttttaggaa
     9541 taatacaaga tataaccaag ctacaaaact tagaaagaaa aataagattt gacttgaatc
     9601 aaaaaggtct ctatgctaga tatacttttg atgatttttt atttaaagat aaattaacta
     9661 aagaatttat tgaagaagct aaaaaaattg gaaaaagtga ttatacaact ttactttatg
     9721 gagaaagtgg gtctggtaaa gaaattatag ctcatagtat acacaacata agtaaaagaa
     9781 aagataggcc ttttgttgct ataaattgtg ctactatagc agaaaattta cttgaaagtg
     9841 aactttttgg ctatgaagaa ggtgcattta ctggtgctag aaagggtgga aaaagaggac
     9901 tatttgaact tgctcatgga gggactcttt ttttagatga aataaatagt ctatccttta
     9961 atattcaaac aaaactatta agagtaatag aagaacgtca aataatgaga attggttctg
    10021 attatataat acctctggat ataaggatta tagcagcaac gaatgaatct ttaaccgaaa
    10081 aaatagttat gggtacattt agagcagact tattttatag attgagtagt ttagagataa
    10141 atatacctcc tttaagagac agaagagaag atataatacc tttgtttaac aattttgtaa
    10201 atgaagtatt aaaggatgat ggtctcaatg gaataaacag tatagatgaa aattttgttt
    10261 tgactaaaga tgaaatggat aagctatata attatagctg gcctggaaat gtaagagagt
    10321 taaagacaat agctcaaaaa tatgttgtga caggtaaaat taaattgaga caagatagag
    10381 attttaaaac taaaaaatta cttcctaact ctgaagtaga caaatttaat tctgaaacga
    10441 cagcaagtgt agaagtccaa gatgaatcta taaatataag taagataaat gatggtaaga
    10501 taagtataga tataaaagaa gtaaataagt atgttgaaga aaaaataata agtatgcttt
    10561 ttgctcaggg actttctaaa aatgaagttg cacaagttct tggaataagc aggacatctt
    10621 tatggaagaa atacaataaa aatatttaaa tataattaca tataaattat tttgaagtaa
    10681 tgttaatttt ttaaaacaag tgttaagaaa aattaacatt acttttttgc aaatttttat
    10741 ttttttagac aggcatatat atttataaga aaaatagtta aaacacttaa tttaataatg
    10801 aaaaaaataa taattctaaa caaaatcaat tttacataaa gtgggattta ttggcatagt
    10861 aattgcttaa tatataatgt aagagtaaat acaattttag gggtgatggt atgagtcaaa
    10921 gtatggttgg taagcatgca atgtggccaa aagaaaatga tgttatattt agcatatctg
    10981 gcagagctca agcagcagag aaggcttttg gtatggataa tgtaataaat gcaacaatag
    11041 gcgctctaat ggatgattca ggaaaattga taacaatgaa aactgtatat gaagaatata
    11101 aagcattaga taactgtgag ataggtgcat atgcagctct tgaaggtcaa ccagattact
    11161 tagaagcagt taaaaaagta tttttcagag attacttacc agaaggacat ataagagtat
    11221 tagcttcacc aggaggaagt ggtgcaataa aattagctgt atggaactat actaatgaag
    11281 gagatgaggt attaacatct gattggttct ggagtccata tgtaagtata gctgaagagg
    11341 ctaatagaaa agtagttaat taccaacttt ttgatgaaaa tagaaggttt aattttgagt
    11401 cgtttaaaga aaaatttgta aatatagcag aaaaacaagg tagagtcttt acaattataa
    11461 acacaccagc gcataatcca actggatata gtgttgcaga tgatgagtgg gataaaatat
    11521 tagacttatc aaaagaagtc gcaaaagata aagacaaaaa gataatattt ttcgtagatt
    11581 cagcatatat tgactttgca ggtgatgatg atgtatgtag aaagtttttt aagaaatttt
    11641 ctaatttgcc tgaaaacgtt ctcgtattgg ttggattcag tatgtcaaaa ggatttacag
    11701 cttatggtat gagaatggga gctataattt gtatatcttc aagtgaagat gtagctgaag
    11761 agttccatta ctcatgtgtt cattcatgta gagcaaattg gtcaaattgt aatagaagtg
    11821 ctatggcagt attatctaac attgtaaatg accctaaaaa attcaaagaa tatgaggatg
    11881 aaaaagaaat atacaaaaac atgcttacta gaagagcaga tgtatttgta aaagaagctg
    11941 aaagagtagg attagaaatt cttccatata tagcaggttt ctttgtaagt ataccatgtg
    12001 ataatccaaa agaagtatgt gaagaattga ctaaacataa tttatttgca gttccattaa
    12061 aaatgggctt aagatttgca gtttgtgcag tttctgaaga taaatgtaag aaagcaccaa
    12121 gtattataaa agaagcactt gaaagtttag aagtaaaaat aaataattaa tttcattgaa
    12181 caaattgggt ggactatgaa tttaataatt gtagatggag ggaattttat atgaaacaat
    12241 tgatgacagg taatgaagca attgcacgtg gagcctatga ggctggtgtt aaatatgcat
    12301 ctgcatatcc agggactcca agtacagaaa tattagaaaa tatagcaaca tataaagatg
    12361 caatagttgc agagtgggct ccaaacgaaa aggtagcact tgaggctgct atagggggtt
    12421 caattgcagg agcaagaaca atggcttcta tgaaacatgt tggtttgaat gttgcagctg
    12481 atccaatatt tacttatgca tatacagggg taaatggtgg tatggtactt attacagcag
    12541 atgagccggg aatgcattca tctcaaaatg agcaagacaa taggatgtat gcaaaatttg
    12601 caaagatacc tttatttgaa ccatcaacta gtcaagaagc taaagatatg ataaaagaag
    12661 cttttgaagt tagtgaaaaa tacgatacac cagttttata tagagttaca acaagacttt
    12721 gtcattcaaa aggattagtg gagtgctatg atagagaaga agttgaaatt aaagagtatg
    12781 ttaaaaatgc taagaaaatg gtaactgttc cagcaaatgc tcaaataaga aggggcgttg
    12841 ttgaagaaag aatggaaatt cttaaaaaat tctcaaatga aactgattta aactactatg
    12901 aaataaatga tacaaaaata ggtgttatag catctggtat gtgttgtaat tttgccaaag
    12961 aagtttttgg aaaaaatgca tcatatatga aactaggatt tacaaatcca ttaccttatg
    13021 aaaaaataaa agaatttgca gaaaaagttg ataaaatata tgttatagaa gaaaatgacc
    13081 catttataga agaacaaata aaagcatatg gaatagattg tattggaaaa gatgtaatac
    13141 caccatatgg agaaatgaca ccagatgttt taagaaaagc tatatttgga aaaacaaatg
    13201 atactataga atacaaatct gaattagtaa caccaagacc accaagtttc tgtgcaggat
    13261 gtccacatag aggattcttc tatgaacttg gaaagagaaa aaatttaata gttggtggag
    13321 atataggttg ttatactctt ggatttgctc ctccatataa tggaatagat tatgttgttt
    13381 gtatgggttc tgcttttgga actgcacatg gagctcaaaa agttcttaat atgaaggatg
    13441 ataatgaaaa aagattggta ggtgtacttg gagactcaac attcttccat acaggaataa
    13501 atggactttt agatgttgtt tacaatagag gtaattctat ttcggttata ttagataata
    13561 gaataactgg aatgacaggt caccaagaaa acccaggttc aggatatact ttacaaggtg
    13621 ctaaaactaa agaagttgat atagaaggat tagttaaagc ttgtggaata gaacatgtaa
    13681 gagttataaa ccctaataat ttaaaagaag taaatgaagc actagattgg gctttagcta
    13741 tagaagatga accatcagta ataataacaa gatggccatg tgtacttaaa aaattctcta
    13801 aagaagatat agaagaattt aataatccat ttaagactaa gtgtaaagtt gaccatgata
    13861 aatgtatagg atgtaaatta tgtttgaaaa ctggatgtcc agctctatca tttgataaag
    13921 agaataagtt atcaaatata gatagaaatc agtgtgtagg atgtggagta tgtgcacaag
    13981 tttgtccaaa acaagcaata gttaaggagg aaaaataata tgactaagag tatacttttg
    14041 gtaggtgtag gaggtcaagg aactatactt gctagtaaat tattaactat gggattgatg
    14101 gaagctggat atgatgtaaa gatgagtgaa atacatggaa tgagtcaaag aggaggttca
    14161 gtttcctcac aagttagata tggagattgt gttcattctc cagttataga aattggtgga
    14221 gcagatatat tagtatcttt tgaaaaaatg gaagctttaa gatggttcaa ttatttaaaa
    14281 ccagaaggaa aagctttagt gaataatcat aggatagatt ctatgactgt tttaatcgga
    14341 ggagctgaat atcaagaaag tgatatagat gcagagttaa gtagattaaa tgcaaaagtt
    14401 ataaatgcag ctgataaagc tgaagaacta ggaaattcaa aaataatgaa tgttatttta
    14461 ttaggatgtc tagttaaatc tatgcaatta gagtctattg attgggaaaa aattataagt
    14521 gaaaatgtta aaccaaaatt tgttgaatta aacataaaag ctttccatga aggtatggaa
    14581 atggttagca aatagtttat aatagatata aatagactat agaaattaag gtgaaaggaa
    14641 gaaaattatg acttacagaa tattagccat aaatccaggt tctacttcta caaaaatagc
    14701 agtatatgat ggagaagaac aaattcttgt gaagacgata gaccatccag ctgaagagat
    14761 tgcaaaatat aatactatac aagaccagtt tgaaatgcgt aaggaagcag ttttgaatat
    14821 tcttaaagaa aatagtatag acttaaaatc tcttagtgca atagtaggaa gaggtggagt
    14881 tttaccacca gtaaaatcag gagcatattt agtaaatgaa gaaatgattg atgtactaag
    14941 acatagacca gtacttgaac acgcttccaa tttaggtgct gttgtggcac atgcaatatc
    15001 agaacctctt ggaatcaact catatattta tgattctgtt gcagtagatg agcttataga
    15061 tgtagcgaga atatctggac tttgtggaat ggatagatca agtgcagggc atgcattaaa
    15121 tactagagca atggctttaa aatatgctaa ggataaagga aaagattata agagcttaaa
    15181 cttaatagta gctcacattg gtggaggagt aagtatttat cttcatgaaa aaggaagaat
    15241 ggttgatatg ctatctgatg atgaaggacc attttctcca gaaaggtcag gaagagtacc
    15301 tgctacaaaa ttagtggctg cctgttattc aggtcaatat tcagaaagag aaatgactaa
    15361 aaagataaga ggtaaaggtg gtatagtttc atacctaaat actgtagatg ctagagaagt
    15421 tgaaaaaatg atagcagaag gaaatgaaga agcaaaaatt atttatgaag caatggctta
    15481 tcagttagca aaaggtattg gagagttagc aactgtagta gatggaaagg tagatgctat
    15541 aattataaca ggtggaattg catattctga aatgtttact tcaatggtta aaaagaaagt
    15601 tgagtttata gcaccagtag aaattatggc aggagaaaat gagttggaat cacttgcttt
    15661 tggaacttta agagtactaa atggagaaga agaagctaga atttatagtg aaaattaata
    15721 agaaaaacta aaaatgttta tatactaaaa aagtggtata tccgtttttt atacacgaaa
    15781 gcttagagta taggtgaaaa tgtataaaat ttggattgcc actttttata attaaaattt
    15841 tatcttaacc taataaataa ttctgtaaaa tttcgtattt atatatatat tttattggta
    15901 tttattgtta ttattattat gaggagtgat ttttgatggg aaaaataagt ttaaaaagta
    15961 tgataagatt attttcaggt ttttttatat ttgcaatttc ttctgtgctt atgattaatg
    16021 cacatgtagg tcttatgcct tgggatgtac ttcaccaagg tttatctata aagctaggca
    16081 taactatagg tcaggcttct ataatggtag gagttgtaat tgttatattg gatgcagttt
    16141 ttggtgaaaa tataggatgg ggtactttac tcaacatgac atttatagga atttttattg
    16201 atttagtaat attttctgga gtgatacctc atgcaagcaa cacttatata ggtgtgttta
    16261 tggttgttat aggaattatt ttggcagcta tagcaagttt tctatactta ggtgtttgtt
    16321 taggaagtgg accgagagat gggcttatga ttgctcttca gaaaaaaact aataaatctg
    16381 tacgtcttgt tagaacaatt cttgaaatac tagcattagt tgttgggtgg ttattaggag
    16441 gttctgtagg tattggtacg cttgtaagtg ctttaggttt aggatatgta ttacaaatag
    16501 tgtttagaat atttaaattt gacacaaaat tgttgaaaca tagatttatt atagatgata
    16561 taagagaatg gaaggaaaag aaaagcaatg aacataaatg taaatcaagt attgtaataa
    16621 aaaatgagca gaattaatta tgctaaaata tatttgtagt ttatctaatt tatagtaaag
    16681 tcaaggagat tttgaaatgg aattatggga tttatataat gctgatggaa ttaaaacagg
    16741 aaatgttata aaaagaggta attctattga agaaggttat taccatttgg cagttgaagt
    16801 gtggatttta aatagtaact ctcaaatttt aattcagaaa aggtctaaaa gtaaaaagac
    16861 attgccaaat atgtggggaa tgacaactgg atgtattgtt tctggggaag acagtttaga
    16921 aggagcaatt cgcgaagcaa aggaagaaat agggatagat ataactaaag atgagatgaa
    16981 agtttttaga agtatgattc atgaagatac tctttgggat gtatacttag ttaaaaaaga
    17041 atatgatata tccaaagcta ttttacagga ggaagaagta agtgatataa agtgggtaag
    17101 cacagatgaa ataagacaat tactaaaaga gggtttgttt tttgaatatc cagagatata
    17161 cgaattgcta tatgagatag ataataataa attaaatata tgatgtagag cagatttcag
    17221 tataagtaag attatttaaa atgtatcttc tctaaatttt aatattgttt tatgaaaatt
    17281 aataagttat ttttagtatt tttctacttg ttttttgaga ttaaaataaa aagggcagtc
    17341 attataaagt cataaaaatt tggggaggat ttaaactatg gaagataaca aaggattggc
    17401 acgtgacagt tcaaaatata aaattgtttc tatatctgtc gtagtaatta ttctaattac
    17461 attttggtat atgttaaata tggtgctttt aacatttatt atgactttta ttttctataa
    17521 cttgcttgta gccacaagaa aacgaattaa gaagttttct tctttaaata ttccagattc
    17581 attaataatt atagtgttat atgcactatt tgctatattg ttagtattga ttagctatgc
    17641 agttgtacca ataattatag ttcaacttac agagttgagt agggttttta gtgattttga
    17701 tgtaaatcaa tttgctcaat ctttaggacc aaaattgtat cctattgtct caaagctgga
    17761 ttttaataaa tatatttcac aagcagggct acttatagca tcaacagcaa caaaagttgg
    17821 aagttttgga gtaaatatat tattggcatt tttactgagt ttactccttt tacttgaaaa
    17881 aaatgaaatt aaaaattttg gagataaact ttctgatagt aagatttctt ttatttataa
    17941 ttcgcttgta ttttttggaa agagctttgt taaaaatttt ggtgaagtaa tgaaagtaca
    18001 agttatgatt gcctttataa attctgttgt ttctatgatt ttcttaggtt tcatgggatt
    18061 ccctcaaata tgggctttag gatttatgat ttttgtgttg ggtcttattc cagtagcagg
    18121 agttatagtg tctttgattc cattaactgt aatagcattt aatacaggag gaataacaaa
    18181 ggtttttgga gttttactta tgatttgtat agtgcatgca gtagaaacat acatattaaa
    18241 ccctaagttg atgtcgaata gaactaaact tccagtttgt tttgttttta ttattttact
    18301 tgtaggagaa cattatttag gtgtatgggg attactaatt ggagttccaa tatttatgtt
    18361 ccttatggat attctgggtg ttaaatttac ttctaggtaa tatattaaaa taataattta
    18421 tctttatata taaattataa attgttttaa aaaagaacct ataaatagac atcattaata
    18481 aagacatcta tttgataggt tcaattttgc tttgtataaa tactataaaa ctaaataaaa
    18541 agaaatttat ttcatttcaa aagtttcaca acttgcattt ctttcattta tatgaacttt
    18601 ttcagctttg caaagttcat ttttattgta tttacatttt acagcttcac aatgaatgtt
    18661 atctgtatca acttggttag tttcattaga acgactagtt ataccagatg tatatttgtc
    18721 ttcaaaagaa gcacaataag tattttctgt agtagttgct tgcattccat ctacttttat
    18781 actaccagca taacaatatc cactagtatt ataagcacaa ttagtagcag cacaatttaa
    18841 attattattt ttcataaata acctcctaag ttttatttaa acttattatg tgaagttatc
    18901 taaattttat acacttattt acaattacat ttatcacatt taacaactac atctttggaa
    18961 gtttcccttc ctaaattttt attaacatga tacacatcaa cattttcagt tgatccacat
    19021 atagaacatt taaaattgtt ttctagtagg gttctttctt taaataactt ccaatacata
    19081 gaattgatgt aatcattata atttaccttg aggcatgtct caagaaagtt tatgtataga
    19141 ttgtctaaat ctcctgtatt taattctgta tattctggtt caaaatattc acaacatcct
    19201 ctaaaatcgg gctttgtatc tgaaataaca catctaatat catatctata gtctaggcta
    19261 ggccccttaa atgaaagatg tgtgcaaaaa gaacaagatg tttctggtag atttttttca
    19321 agttcatgta atttattatt cataagtatt cctccaaaaa atttatttta agtatataaa
    19381 cgaatagatt attttaaaac ttttatttat ttatattaga gatttaggat aaatattcca
    19441 ataaggagta aatacttaag tatttattac tgtattaaat aaaaaagagg caaatctaac
    19501 ttgagattgc ctactttttt atcatttttt aataaaattt attctaagta ttattttatt
    19561 tagatttagt cagccaactt agtatctgct ttgcttttta actttctacc agagcgtaca
    19621 gttaaaatag catataatac agtaaatatg gcagctaaaa catatgatat atttatgttt
    19681 aagttaaatc caatttgagc attaaatata taactgaata taacaaagga ataaaacata
    19741 ccaggaatta agcttataat ataattcttt tcttttatta taaggtaaac tgtaatcatt
    19801 gcaaatgcaa atatggcaat agtttgatta ctccaagaga agtatctcca caatatatta
    19861 aatccagaag cactaagctt tgcaaatata aggatggcta tgacaggaat aaatatacag
    19921 attgacaata taacacgatg ttttttttcc ttttggtcat aatgaaagta atctgcaagc
    19981 attaatctta aagatcttaa agctgtatct ccagaagtta ttggtaaaac aattacacct
    20041 attatagcta tgataccacc aatagaacca agtaaatctc ttgcaaccaa acctattaca
    20101 tcaggagaac ctactaattc cttaggtatt cctttattgt aaatacccat agcagctgca
    20161 gcccaaatca ttgcaattaa accttctaaa atcatcatat tataaaaagt agtttttcct
    20221 tctttttcat ttgaaactga tcttgctata agagtagctt gagttgagtg gaatccagaa
    20281 acaataccac aagcaactgt aacaaagaat gtaggaataa gaggaatacc atcaggatga
    20341 atacctttcc aatttgcaag acttaaatta gctaaatcat aaccttgtgt aaagattcca
    20401 attccaacac cagcagcaga taaaagtaga atagctccaa atattggata tacctttcct
    20461 atgattttat caattggaaa tagtgttgca cacaagtaat atagaaagat aagtccataa
    20521 actatccaga caactggatt atttatagtc gatttcatat ttaaaatttg agtaacaact
    20581 aaatccccag gtgtataaat aaaaactgca ccaactaaaa gcattaaaag acaaaggaat
    20641 atattataga cttgaaatac tttattacct aaaaatctac tgataagaga aggcatttgt
    20701 gctccttttt ctcttatact aatcattcca ctcatatagt catgcaaagc tcctccaaat
    20761 acacagccaa taggtattag tatgaatgct attggaccaa acaatatacc ttggataggt
    20821 cctagaattg gtcctgtacc agctatatta agcaactcaa ttagactatt tttccatttt
    20881 ttcattggga catagtctac tccatcactt tgagcaagtg caggtgtttt tctgtcatct
    20941 gggccaaata ctttttcaca ataagcaccg tataaagcac ctcctattag taatatagcc
    21001 aagccgatta agaatgttgt cataatatca ccccatttat aaaatttttt ggtctttgta
    21061 tacatattat ctaaatgtgt agatttatat tgaatttaat tctggacaac ctacaaattc
    21121 tataaagtat tacaactaat ataatttcag aaataaatac atatacataa ccatgtactt
    21181 agtatacagg tatttggtaa tattttcaat gttatagcaa taaagaatat agacaaaatt
    21241 ctgataatat tttacaaaaa aattaaaaaa tataaaaatt agtttaaata gatggagaaa
    21301 aaaggaaaat caattgagaa tataaatgtc tatatcttaa caatattaag aggtttaaaa
    21361 ttcttgaaga aagaatagtc aagtgatata atgagtttac aggtgtatat acactagtac
    21421 atatagaaag cggtgcaatt atggataaag atttaacata tcaaatcaaa gagctaaaga
    21481 aagaaaaaaa tgcaataata cttgcccatt tttatcaacc accagaaata caagaattag
    21541 cagatgcagt tggtgactca tattatttaa gtgagattgc tagagattgt aaagaagaag
    21601 tggttgtatt ttgtggagta aggtttatgg gagaaagtgc taagatatta tcacctgaaa
    21661 aaactgtatt gatgccagta agtaacgctg ggtgtgctat ggcagatatg gtagatgaag
    21721 aaggcgtgat aaaattaaaa caacagtatc caaatgcttt ggttgtatgt tatataaact
    21781 ctacagctaa agttaaggca cattgtgatg tttctgttac atcttctagt gcaattaaaa
    21841 tactagaaaa catagataat aaagaaatta tattccttcc agataaaaat ttaggaggat
    21901 atattgcaga acaatttcca gataaaaact ttatattttg ggacggatat tgtaaatacc
    21961 ataacaatat aagagctgaa gaaataattg agttaaaaga taagtataaa aatgcagaag
    22021 tattagtaca tccagaatgt aaaaaagaaa taagagattt aggagattat gtaggtagta
    22081 catcaggaat aataaaatat gctactaata gtaaaaacaa agactttata atagcaactg
    22141 aagaaggtat attacatgaa ttaaagaaaa ataatcctaa taaaaacttt tatattcctg
    22201 gtggaaaaat actatgtaca gatatgaaaa agacaacatt agaaaattta tatagtacac
    22261 ttaaaaatat ggaaaatgaa gttattgtag aagatgaaat catggaaaag gctttaaatt
    22321 cactgcttaa catgcacaaa ttagcagaag gatagaggga tagacttatg aatttagaac
    22381 aagatgtttt aatagttgga agtggagttt caggattata ctgtgcatta aatttagata
    22441 aaagtttaaa tgtgctagta gtatcgaaat caacaattga aaacaacaat acatatcttg
    22501 cacaaggtgg aatttcaact gctagaaata ttgatgatat agaatccttt gtagaagata
    22561 caatgaaggc tgggcagtat aaaaatagag ttgaagcagt tcaagtactt gcagatgaat
    22621 ctatagaaaa tgtagggcag atagtagaat atggtatgcc tttagacaaa gaaaatggag
    22681 agatagatta cacaagagaa ggagcacata gtgtaaatcg aatagttcat agtaaggata
    22741 atactggaga agttgttttt aaaactttat taaaagaagc taaaactaga gaaaatataa
    22801 ctcttataga agatgcctat cttttagata tattaaaaga tggcaataaa tgtataggag
    22861 ctagaatttt taaatctaaa aaagagattc atgttttttc aaaaatagta gttttagcta
    22921 caggtggaat tggtgggctt tttaaaaatt ctactaatca aagacatctt acaggtgatg
    22981 gaattgcaat agctttaaga aataatataa aaatagaaaa tttagaatat attcaaatac
    23041 atcctacagc cttttatgaa gaaaataatg aaggtaggag aatgcttata tctgaatcat
    23101 taagaggaga gggagctaaa cttttaaata aaaataaaga aagatttgtg gatgaacttc
    23161 ttcctagaga tgtagtttca aaagctattt ttgagcaaat ggaaaaagat aaattacctt
    23221 atgtgtattt agatgcaaca catttagata gtgaatattt aattaataga ttttctttta
    23281 tttataatga atgtttagct agaggaacag acataacgaa agaatgtata aaggtatctc
    23341 ctgcacaaca ttattttatg ggcgggatac atgtagattt ggattcaaaa acatctatgg
    23401 aaaatttata tgcagttggt gaaattagtt gtacaggtgt tcatggagcc aatagattgg
    23461 caagtaattc attacttgaa gggcttgtat tttcaaaaag agcagctaaa aatataaact
    23521 cagttataga taatgtaaaa gttaagttta tagatgtacc agatatggat atagatatag
    23581 aacaggtaaa aaaagaaaat aaaatattag tcataaaaga aattgaaaga acaagtgagg
    23641 attttggcga tgaattattt gattattgat agaatgatac aggatgcttt gatagaagat
    23701 gttccaagtg aagatataac aactaattct attgtggatg aaaattctaa atctactgta
    23761 gatttaattt gtaaacaaga tggtataata gctggcttag gtgtatttaa gagagttttt
    23821 gagatacttg gtgatgtaga tgtaaaatta tataaaaatg atggtgatag agtaaagaat
    23881 cgtgaaaaga tagctgtatt aacaggtagt actagaaact tacttgtagg agagcgtgta
    23941 gcattgaatt atttacagag aatgagtggt atagctacta ttacaagtag gtatgttgaa
    24001 aagcttgaag gtacaaatac aaaattatta gatagtagaa aaacgatacc taatcttaga
    24061 atattagata agtattctgt taaagtaggt ggaggatgca atcatagatt taatttatct
    24121 gatggaatat tgcttaaaga caaccatatt ggggctgctg gtagtgttaa gaaggcagtt
    24181 gaattagcta gaaaaaatac ttcttttgtt agaaagatag aagtggaagt ggaaacttta
    24241 gacatggtaa aagaagcaat agaagctaat gcagatataa taatgttgga taatatgagt
    24301 ttggaaatgg caaaacaagc agtagatatt ataaatggaa gagccattgt agaattttcc
    24361 ggaaatgtaa atttagatac tatagaagat ataggaaaaa ttggtgtgga tgttgtttct
    24421 gtaggagcgc ttacacattc tgttaaagct ctcgatataa gtatgaagaa tttgagaaat
    24481 atataaattt tatattgaaa taaacttaat taaaatagac tccttaaatt tgttttataa
    24541 atttaaggag tctatttttt attcattaaa attaataaaa atagaaaaaa atcaatcaat
    24601 aatttaataa aaatagataa atactatata cacttttaat aatatagtta atatctattt
    24661 tacagataaa taagaataaa cttataatat aattgtatct gtaaaatttt gtaaaatata
    24721 aaaagtatag ggggaataaa aatgaaagta gcttatattt ttagtagtac taatacacat
    24781 aaaattctag acaaaatgat aataccacaa cttgaacaag gaactcatgg agtagacgtt
    24841 ctagggatgt ttttctttat ggataatacc ttatttttat ctaaaggtaa tcctgtaggc
    24901 gagagactaa gtaaattaca tgaaaaaact gatatgataa taatggcttg tgaccaatgt
    24961 gctatagaaa gaggtataga gaataatttg gttgatggag ctacaattgg atgtttccca
    25021 aacctatatg cttgtttagg cagtgcaggt gtggaccaag ttataacgtt ataaattagt
    25081 ataggataca atccatagaa aaatttattt tctgtggatt attttaagta aaagataaat
    25141 tgtttaaagt aggggattaa caaatgtcta aaattttagt tgaatttata aacacttgac
    25201 catcttgtga tgaacatgga gtgtttataa aaaaaatgtc agaaaaatat gctgataaat
    25261 tggaaataaa attatatcaa gcagggaaag atttttcgta tataaaaaaa tatgggatta
    25321 taacaaaagg aactttaata ataaatcaga aaaagaaata tgatagatta aataaagata
    25381 caattgaaag ggcaatagta gaagctataa acaataatta aaagtttaaa aattaggagt
    25441 atcaaaaatg aatatattag aaattgtttt aaatggagtt aaagatacta tagtagcttc
    25501 tatagttaca ctgaatggag catcaggatg gcttatgata agttttatat tggcaggtgt
    25561 acttcacaat gttttaactc caagaaggtt tcaaaaacaa cttggaaata agaaattttc
    25621 ttctttaatt aaaagtacta tctcaggaat gtttttacca atatgtagtt gtggagtaat
    25681 accacttgga ataagtatgt attattcagg agcatattta ggaccagtac ttgcttttat
    25741 gacatcaact ccaataataa atccaatagc tgtagttctt tgtctaggtc ttttaggtcc
    25801 taaagttaca atcatttatc taatagctgg ttttttagta ccatttttag taggattttt
    25861 aggaaattgt tttggaaaag aagaattatc acttcataat gattcagagg aagaagtaat
    25921 agaattagaa gaagaaaaaa gaagttttat gggaaatatg attgatggtc ttaaatggtc
    25981 ttttggtgaa ttagccctta ctattagtaa atatgtagta atgggtatgg tttttgcagg
    26041 atttataaca actatttttc caaatagtat aattcaaaaa tatttaggaa atccaggttt
    26101 gctatctctt ggaagtatag caatacttgc atgtgttatg tatgtatgtg ctgtaggaca
    26161 tataccgttt atagcagccc ttgttgcaag tggagcatct cctggtatag cgataacatt
    26221 tctaatagct ggagcagcta caaatctacc agaacttata agtatgttta aacttattgg
    26281 aaaaagaact gttattatat attctgtaac tttgacactg tcttcaataa taattggata
    26341 tataacaaat ttacttttag tgaataataa ctcagtaaat ttagatgcaa caaattcttc
    26401 aatacagttg gcaaataaac taatgttaaa tatacctgat agttttgagt atgtatgtac
    26461 tattttaatt attttatttg catttaaatc aataatacca aagatgaaag aggtcatagg
    26521 aaatcatgct taaaaagata gttataatat cctgtatagt agttgtgtta atcattttat
    26581 caaaaatagt tgatgataac atcaaagaag atgcttctat tccaaatgtg aataaagaaa
    26641 cattagaata ttttagaaaa aattataaag aagacataat aacttgtgct gaagaagact
    26701 taaataatga tggaaaaaaa gatttagtag ttatatataa aaaaagcaat aattcaaatg
    26761 aaatggtagt cgtagtttct gataaaaata gccactatat aacaaagcca ataccagcac
    26821 ctatagagaa tcaaacgata acctttaaaa atattgatga taaagcacca atagaagtaa
    26881 ttgtatcagg gtctaaaaat ggtaatgtag gatatgctat ttacagagta gagggtaaaa
    26941 aatttgttga tttatttggc gaagatatgg acaaatgttg ctaaaaataa aaataataca
    27001 taaaggtggg aaatttatat gaaattatct aagaagattc aagcattaat cttatttggt
    27061 gtaatgggta catctatatt aacaggatgt agtagtaaac caaaagaaaa agaagaagca
    27121 aaaactggaa aagatgatta tacaataaca gtaggttatt ataattgtga ccatatgact
    27181 gcgggaccag tagcagaatc ggcaggaata tataaagatt taggtcttaa tgtaaaaact
    27241 gttggaaatg gtaaagttcc tgaagctatg gcagcaggaa aaatggatgc aggttacata
    27301 ggaactaagg ggttagttgg agcaatacct aagggttcgc caataacaat agcagctaac
    27361 aaccatactg gtggttctga atatttaata gtttcaaaag atataaaaga acctaaagat
    27421 ttaataggta aaaaaattgc aacagatatg agtgatttct tatggacaag tgattatggt
    27481 ccagaaacag gtctaccaac tgacccatca aaatatgaag ttgtaaatat ggattcagac
    27541 aaagataaat atttagctct taaaactggg aaaattcaag cttttacatc ttgtgaccct
    27601 tggggttctg tagctgaaaa tgacggtgca ggaaaaataa tagcatctac tcaatataaa
    27661 gaaaaagcta atggcaaaga atataactgt tgttcattct cattaaacaa aaactttata
    27721 aaagaacatc cagatttagc aaaaaaattg gttctagcac atacaaaagc aatagaatat
    27781 atatatacaa atccagctga agcagctaaa atatttgcaa aatattataa tgtagaagaa
    27841 gaagttgcac ttagaactat ctataagaag actgttggag aaggtagaac tcttacttgg
    27901 aaagttacag gtgaagaata taaaaataat ttacaaatgt ataaagattt aaaggcttta
    27961 gatgatatac ctaaatatga agatacgatt gatacaagct tattggactc ttgtggagct
    28021 gatgattttg acaaatttat aaaagaaaaa gttaacccag agtttcctga aggtatgagt
    28081 tatgaagact ggaaagcaaa ggtattataa ataaatggag aatatgaaaa atataataat
    28141 actttttatc attattttgg gaagtatatt tataatattt tttaattttg aagataaaga
    28201 agaaataaaa ggaaaattaa gaataggggt atctgatgat acctctggtt ttgtaataaa
    28261 ttatatggta aatagagact actttgaaaa tataaaagta agtgatataa tggatatttt
    28321 tacaattaat gattgctgag caagtacaat gcagtgggct ctgagttcag aggaaataga
    28381 tatagcaatc atatgtaaag atgctgcaaa acaatatgta aatgtaaata gtggatttga
    28441 aattgttggt actgtagttc aaaattctga tatatttcta ttaagtgata ataatcctga
    28501 aaagatagga gtcattcaaa atagagatta ccagtcagaa ttggttaaaa aatactacaa
    28561 gaatgtggaa gtagctccct tattagggac tgcactagca tatggattag aaagtaattt
    28621 agtagatggt gttgtaatag attgcataaa gtcaattggg ttagagggta aaagaaaatc
    28681 tacaactaaa ttaggagatt atgataccta tgtattagtt gtaaataaag agtttaaaaa
    28741 aagtaaagca tatagtgatt ttataacact ttacaataaa agtgttgatg ctttaaagaa
    28801 taaagctaca tttaagaaag tattaaaaga gtacaggaat ataagaaata tagatatgga
    28861 ggaaataagc aattggaaat taaaatttct aaagataaaa gcgatagatt aactaagaaa
    28921 aaaactgatg gtagtatgga tattttatat aaaataatac tattagttat tatattttta
    28981 gtctggcatt ttgcagcaaa agatataggg agttctttgt tacttccaat gccagtagat
    29041 gtaataaaag gtttcttttt ctgtgtgaca gatgcagaga cagtcactaa tctttttata
    29101 acattgcaga gagtacttaa aggttttatg tatgcattat tgtttgggct tccaatagga
    29161 tttattatgg gattttctaa aacttttgaa agggttttat ctccagtagt agattctgta
    29221 aggcaagttc caataatggc atgggttcct cttactatag tatggtttgg tataggagat
    29281 ggtccaacaa tatttttaat agctttttca ggggttttcc ctataatttt aaatactatt
    29341 caaggagtaa gagcaatatc aaaggattat tataatgcag ctagaagtat gggagcatcg
    29401 ccaattgtga tatttacaaa tgtaattgtt cccgcatctc ttccagatat actaactggt
    29461 tcaaggattg ctataagtac aggatggatg tctgttatct gagccgagtt tatagctacg
    29521 agtgccggtc tcggttactc aatggtacaa gctcaaacat taatgcatac agatgtatta
    29581 attgggctta tgatatttgc agctttaata ggatttataa tagatagggt attaaagttt
    29641 ataaataaaa tcctttgtag atggaggttt gcagattaat gaagttaagt gtaagagata
    29701 taaataagac atttgtaaat aatagagtac atacaaaggt tttagaagat ataagtatgg
    29761 atatagatga tggacaattt gtctgtcttt taggaccatc aggttgtgga aaaacaactt
    29821 tacttactat aataggtggg tttcaaaaat cagaacgtgg agatgttttt ataaatgata
    29881 aaagagttaa aaaaccgggc atagatagag cttttatatt tcaaaattat gctttatttc
    29941 cttggaaaac tataagaggt aatgttctat ttcctatgaa acagcagaaa ataccaaaag
    30001 aaaaaagaga agaaatgcta gaagaacttt tggttatgtc agacttgaaa ggaaaagaaa
    30061 aactgtttcc gcatcaatta tctggaggaa tgaaacaaag agtggccatg ataagagctt
    30121 tagcatgtaa tccagaggta ttactaatgg atgaaccatt aggagctgta gattttcaaa
    30181 tgagacaaaa tttacaggaa gagctagaac gaatatggat aaagaagaaa ataactgcat
    30241 taatggtaac tcatgatgtt gatgaagctg tatatatgag tgatagagtt atagtaatgt
    30301 cgagagataa aggaagaatt attgatgata taaatataga tattccaaga cctagaatta
    30361 gaggaagcca aaaatatgaa gagtacaaaa acaaattaac tgatacttta tcaaagtgtt
    30421 atgaagttta aagaggagta gacatgagtc aaatagaaaa atacaatagt ttggataata
    30481 cacaacagaa aataagaatc tctattatgg atatgataat agataaaggt tctagtgtta
    30541 cacttcaaga agtgactgaa tatgtaagta aaaagttgaa tatagaaaaa gaatatatag
    30601 aaaggacact acaatatttt atttataaaa atataatggt tgttgatggg aatagtataa
    30661 attttatata tcctgtatca gcattgccaa caaatcataa agtaactttg agagataata
    30721 gaagtttcag tgcaatgtgt gctatagatg ctataggaac ctcttgcaca ttcaaccaag
    30781 atataaaaat aaactctatt tgtagtgcta caggtaagga aatagaagta attataaaaa
    30841 atgaaaagat tgagtatgtg aataatccaa acttaagagt gcttcatata aatcttgata
    30901 agcatctaaa ttgggctgct agttgctgaa atataatgaa tttcttctgg acgaagagtg
    30961 attttgatgc ttggacaaac gaagcgggat tatctgatga tgaagatata tattgtttag
    31021 atattaatga ggcaatagta gaatcatata aaatatttaa actcaaacaa aaggtactat
    31081 catagatata catatatgaa aaactaaaaa tgacctttag ataaaaatga taggtaatat
    31141 ccatactata taaattagta tagagtaggg atgtgaaaag tatttaaatc taaaggtata
    31201 tttttagttt ttttagatga ttagatagcc ttattaagta tatatttatt tataaccttt
    31261 gcaactccat tttcattatt agtatcagta acataatctg caatttcctt tatactatta
    31321 cgtgcattcc ccatagccac accaagacct gcatacttta tcatatgttg gtcattttct
    31381 tcatcgccaa cagcaatagc attttctata ggtatattta gattcgtaca taatgtttta
    31441 agagcagttc ctttattagt agttttacct aaaaattcta gataaaaagg agcagacctt
    31501 actatagtat atttattgaa taaattttta ggtagttgct gtatgatttc ttccaatctt
    31561 tctggttcat caactatcat aattttacag attttaatag attcatcaat tttatctttt
    31621 tgtatatatt tgacttctat attatttaat ttcgcttcat gaagtgtata tttgccaggc
    31681 gtttcatttg gtgtaattaa atttgtcatt gtatttatgt gtattttagt cttatatttt
    31741 ttacaaacgt tattatatat aaaatcaaaa tcatctaaac tcatttctac atcatgtatg
    31801 attttctcac ttttaacttc ttgaataatt gctccattaa agcatataac ataatcacct
    31861 tcatctgtta aatttagttg atttagaagt tcttttacac caggaagagg tctgcctgtt
    31921 gttataacta cttttgcccc agcccttttt gcctcctgaa tggactcaaa gacttcagga
    31981 gtaatccttt tttgtgtatt taatattgtt ccatcaatgt ctagtgcgat taatttgtac
    32041 atatcaacct ccaataaatt atatactcaa atttcctgtg aaaacgttga cacagctagt
    32101 gttgaacaaa gtttcagtgg gaaatatggt ttgttttgta tactattata tcaagagata
    32161 agtaatttag aaagtttaat aatattaatt ttttgataaa aatattactt atgtgagatg
    32221 agaatgtaaa aactttgtaa tcaataattc caaaattctt aattacaaat aatggtatcg
    32281 tttgcattgt taatataaat aaatgtatat tatatagtta gaagtttgaa taaatagact
    32341 gatggtaatt tgttatatta gttagttttg tgttataaaa tattgtaatt ccattaatca
    32401 tatgttatta ttcaacatga ttataatata aagaatattt gatatatata ataatttata
    32461 aaagagtatt acatagtaca tataaatcta tatttataaa tacaataaag taaagttgta
    32521 aaggagtgct ttaaatgaag ttttcagagt ttaagtatga aagacccaat tataatagta
    32581 tgaaaaaaga gtttttgagt tgtgtagaag atataaataa ttctcgtaat tataaagagc
    32641 aacaaaaaaa tatacataag attaatttat taagaaataa aatagaaacg ttgtcaaata
    32701 tagcttcgat aagatatagt acagacacat ttaataaatt ctacaaagaa gaaaaaaatt
    32761 attgggatga atatatgcct ttgtatgaag aattaaattc atatttttat aatgccattg
    32821 taaattcaaa atttaaatat gatttgataa aagagtttgg agagcaattt ttcacaatag
    32881 tagagtattc tttaaaaagt ttttccaaag aaataataag tgaattgcag gaagaaaata
    32941 aattgtgttc agagtatact agacttttag cttcagctga gataatgttt gatgggaaaa
    33001 taagaaattt atctggtatg gggaaattca tgtattctaa gaatagaaaa acaagagaat
    33061 tagcaaacaa agcatattat aatttctttg aagaaaatga aactaaattt gatgatatat
    33121 ttgataaatt ggttaaactt agagataaga tgtctaaaaa attaggtttt gaagattttg
    33181 tagagcttgg gtacattaga atgatgagaa gtgactacag agaatatatg ataaaaaatg
    33241 ttagaaaaca agtactaaaa tatgttgttc caatggcaaa tgagctttat gaaaaacaag
    33301 ctaaaagaat tggtctagaa tatttaagtt acatagatga aggcgtggaa tttttaacag
    33361 gaaatgcaag tttaaaggga gattcaagat acataattaa aaatggtaaa aggatgtatt
    33421 ctgaactgtc aaaagaaaca aatgaatttt ttgattttat gttagaaaat gaacttatgg
    33481 atttagaaac gaagaaagga aaaggagctg gagggtattg tacttatata ccagattata
    33541 agtcaccatt cattttttct aattttaatc aaactgctga tgatatagat gtattaacac
    33601 atgaggcagg acatgcattt cagttgtata tgtctagatg gattgatatg ccagaaatta
    33661 attttccaac gcttgatagt tgtgaaatcc attcaatgag tatggaattt ataacatggc
    33721 cgtggatgga tttatttttt aaagaagata cagataagta caaattcact cacttatcat
    33781 cttcaattaa atttatacct tatggagtaa ttgttgatga atttcaacac tatatttaca
    33841 aaaatcctaa tgtagataag tcaaaacgaa aagaaatctg gagattttta gagaaaaaat
    33901 acttacctca tagaaaatat ggtgataatt cttttttaga gagaggttgt tggtggttta
    33961 aacaaggaca tatatttaaa aatccgtttt attatataga ttatgtatta gctcaaattt
    34021 gtgcgttaca attttggaaa aaaatgattc aagatagaga tgcaggatgg aaagattata
    34081 taaatatctg taaagttgga ggaacaaaat catttttaga tattgtgagt atgggaaatt
    34141 tgtattctcc atttgatgat ggctgtattg agtctattat aggtgatgtt aaatcttggt
    34201 ttgatgaaat aaatgacagc aaattataaa aaattatgag aattttattg tataaaagta
    34261 aaaaattaaa aaatatataa aaagtgatta tttgttgtga aaatagtctt gtttttaact
    34321 aaattgataa aataaactaa aaaagatttg tacttaaaaa aaaaagaaaa tacaagaaat
    34381 atgcaatatc aacatttgga aaaaaaagta aaaatgtata caaaatacat ataaaaaaac
    34441 tattgcaaat tttatagaat gtttatatac ttaagtcaac agagatagaa aaaagctatt
    34501 tatagaaaac aaaggataaa ttgcttaatt ttaaattttc tgaaaaaaat aataatccgg
    34561 atgaagagta tgggagactg ctttataaaa agcgaccgaa gggacaagtt taatcttact
    34621 tacccaaaag attagatgaa attctcaggt aaaggtgact gtacttggac ggggctctga
    34681 aaatgatttt aacagggaag acaaattggg agatttgttt ttcctgtttt ttatttatca
    34741 agtaataaat aaaagtttga aagagagtaa aaaaatgata ataattacga ataatccaaa
    34801 agtaaaagaa gaagttcaag gcagagaagt tttgtttaaa gacacaactt atattggaat
    34861 cttagaagca agtagagatt tgatacatga aggttatgaa cttttatctc atccactcta
    34921 tgggagtgta aagccaaatg aaacacctta caggactgtt atactaaaga aaggaaatcg
    34981 tttggatata aactctttaa ccttaattga agaagcaatc atcactgcaa gtaaatttca
    35041 gaataataaa aagactccaa aatggacaga aagtgttcaa gatgatttta gagtaattga
    35101 ttatgatata ttttataata caatacaaag aatgcagtat gaataaaaaa attgttaaaa
    35161 agttattaaa acagcctaaa tattaaatct aatttaatat taaataaaat gagaaattta
    35221 attggggagg ataagtcaaa atggaaaatg tgtatgactt agtaataatt ggttcaggac
    35281 cagcagggct tgcagcaggt ctttatggag caagagcaaa gttaaaaact ctaatcctag
    35341 aaaaagacaa gactggtgga caaattgtaa taacacatga aattgcaaat tatccagggt
    35401 cagttccaaa tgcaacagga ccaagtttaa tagctagaat ggttgaacag tgtaaagagt
    35461 ttggagcaga aatgctaaga gacaacattg ttgatactga gctagatgga gatataaaag
    35521 ttttaaaagg ggaaaaggca gaatatagag caaaagcagt aataatagga acaggagcaa
    35581 caccaagaaa gattggttgt cctggagaaa aagaacttac tggtaaaggg gtttcatatt
    35641 gtgcaacttg tgatgcagat ttctttgaag attttgaagt atttgttgta ggtggaggag
    35701 acagtgcatt agaagaagca atgtatttaa ctaaatttgc tagaaaagta acaattgtac
    35761 atagaagaca aggatttaga tgtgctaaga gtgttgaaga aaaagcaaaa gctaatccaa
    35821 agatagagtt tttattagat acagtaattg aagaaatcaa aggtgatgga atattagaat
    35881 cagttgtatt taaaaataaa gttactggag aaactcatga atactttgca gatgaagaag
    35941 atggaacaat gggagtattt gtgttcgttg gattagatgc tcaaactgat ttattcaaag
    36001 gtaaagttga tatggatgaa aaaggttaca taataactga tgaagatatg agaactaaca
    36061 taccaggcgt atttgcagca ggagattgta gatctaagac tctaagacag gttgtaactg
    36121 caactaatga tggagcaatt gcatctatag tagctgagaa atacattgat gaaaaatttg
    36181 ggaactagaa tctgtaaatt aagaaatagt gtctgtaaat ttaatgaata atatttaaaa
    36241 ttaaaattaa tatttaaaat aaaaataaaa atttcaaggg ggaataagaa aatgttagat
    36301 ttagataagg ctacatttga agaagaagtt ttaaatgcag aaggttttgt atttgttgat
    36361 ttttggagtg aaggttgtga gccttgtaaa gctttaatgc cagatgttca taaattagct
    36421 gagacttatg gggataaaat aaaattctgt aagatggata caacaaaagc tagaagatta
    36481 gctataaaac aaaaagtatt aggtcttcca actatggcta tatacaaaga tggagaaaaa
    36541 gtagacgaag ttactaagga tgatgctaca gttcctaata tagaaaacat gattaaaaaa
    36601 tatctttaat atgttgataa attattaaca ttaaaagaaa aaatctattt ttatct
//
LOCUS       DAEHWO010000036        34744 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEHWO010000036 DAEHWO010000000
VERSION     DAEHWO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34744
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.036"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(60..716)
                     /locus_tag="KNP54_002119"
     CDS             complement(60..716)
                     /locus_tag="KNP54_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0893018.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(771..1400)
                     /locus_tag="KNP54_002120"
     CDS             complement(771..1400)
                     /locus_tag="KNP54_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBF0893019.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1531..2172)
                     /locus_tag="KNP54_002121"
     CDS             complement(1531..2172)
                     /locus_tag="KNP54_002121"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBF0893020.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2181..2852)
                     /locus_tag="KNP54_002122"
     CDS             complement(2181..2852)
                     /locus_tag="KNP54_002122"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBF0893021.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2857..3741)
                     /gene="rsgA"
                     /locus_tag="KNP54_002123"
     CDS             complement(2857..3741)
                     /gene="rsgA"
                     /locus_tag="KNP54_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBF0893022.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDENEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3839..4576)
                     /locus_tag="KNP54_002124"
     CDS             complement(3839..4576)
                     /locus_tag="KNP54_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBF0893023.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4684..6699)
                     /gene="pknB"
                     /locus_tag="KNP54_002125"
     CDS             complement(4684..6699)
                     /gene="pknB"
                     /locus_tag="KNP54_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBF0893024.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6716..7468)
                     /locus_tag="KNP54_002126"
     CDS             complement(6716..7468)
                     /locus_tag="KNP54_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBF0893025.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7488..8519)
                     /gene="rlmN"
                     /locus_tag="KNP54_002127"
     CDS             complement(7488..8519)
                     /gene="rlmN"
                     /locus_tag="KNP54_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBF0893026.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8527..9852)
                     /gene="rsmB"
                     /locus_tag="KNP54_002128"
     CDS             complement(8527..9852)
                     /gene="rsmB"
                     /locus_tag="KNP54_002128"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBF0893027.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9914..10615)
                     /locus_tag="KNP54_002129"
     CDS             complement(9914..10615)
                     /locus_tag="KNP54_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBF0893028.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10684..11436)
                     /locus_tag="KNP54_002130"
     CDS             complement(10684..11436)
                     /locus_tag="KNP54_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBF0893029.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDIMDIEKAIGFLTGKNILVCN"
     gene            complement(11446..12375)
                     /locus_tag="KNP54_002131"
     CDS             complement(11446..12375)
                     /locus_tag="KNP54_002131"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBF0893030.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12390..12830)
                     /gene="def"
                     /locus_tag="KNP54_002132"
     CDS             complement(12390..12830)
                     /gene="def"
                     /locus_tag="KNP54_002132"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBF0893031.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12848..15373)
                     /gene="priA"
                     /locus_tag="KNP54_002133"
     CDS             complement(12848..15373)
                     /gene="priA"
                     /locus_tag="KNP54_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBF0893032.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15612..16811)
                     /gene="coaBC"
                     /locus_tag="KNP54_002134"
     CDS             complement(15612..16811)
                     /gene="coaBC"
                     /locus_tag="KNP54_002134"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBF0893033.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16816..17082)
                     /locus_tag="KNP54_002135"
     CDS             complement(16816..17082)
                     /locus_tag="KNP54_002135"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBF0893034.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17085..17702)
                     /gene="gmk"
                     /locus_tag="KNP54_002136"
     CDS             complement(17085..17702)
                     /gene="gmk"
                     /locus_tag="KNP54_002136"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBF0893035.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLKELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17732..18613)
                     /locus_tag="KNP54_002137"
     CDS             complement(17732..18613)
                     /locus_tag="KNP54_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBF0893036.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18617..19447)
                     /locus_tag="KNP54_002138"
     CDS             complement(18617..19447)
                     /locus_tag="KNP54_002138"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBF0893037.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(19734..20768)
                     /gene="ltaE"
                     /locus_tag="KNP54_002139"
     CDS             complement(19734..20768)
                     /gene="ltaE"
                     /locus_tag="KNP54_002139"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBF0893038.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21064..22839
                     /locus_tag="KNP54_002140"
     CDS             21064..22839
                     /locus_tag="KNP54_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBF0893039.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23054..24706)
                     /gene="abc-f"
                     /locus_tag="KNP54_002141"
     CDS             complement(23054..24706)
                     /gene="abc-f"
                     /locus_tag="KNP54_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HBF0893040.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(25005..26216)
                     /locus_tag="KNP54_002142"
     CDS             complement(25005..26216)
                     /locus_tag="KNP54_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBF0893041.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26500..27033)
                     /gene="pyrR"
                     /locus_tag="KNP54_002143"
     CDS             complement(26500..27033)
                     /gene="pyrR"
                     /locus_tag="KNP54_002143"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBF0893042.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27393..28340)
                     /locus_tag="KNP54_002144"
     CDS             complement(27393..28340)
                     /locus_tag="KNP54_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBF0893043.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(28309..28755)
                     /gene="lspA"
                     /locus_tag="KNP54_002145"
     CDS             complement(28309..28755)
                     /gene="lspA"
                     /locus_tag="KNP54_002145"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBF0893044.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLVDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29065..29844)
                     /locus_tag="KNP54_002146"
     CDS             complement(29065..29844)
                     /locus_tag="KNP54_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBF0893045.1"
                     /translation="MKKIICGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29899..30381)
                     /locus_tag="KNP54_002147"
     CDS             complement(29899..30381)
                     /locus_tag="KNP54_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBF0893046.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(30647..32068)
                     /locus_tag="KNP54_002148"
     CDS             complement(30647..32068)
                     /locus_tag="KNP54_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBF0893047.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(32214..32984)
                     /locus_tag="KNP54_002149"
                     /pseudo
     CDS             complement(32214..32984)
                     /locus_tag="KNP54_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(32989..34191)
                     /locus_tag="KNP54_002150"
     CDS             complement(32989..34191)
                     /locus_tag="KNP54_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBF0893048.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        11059 a         6384 c         3485 g        13816 t
ORIGIN      
        1 tatttatttt taatttattt tgtttttaat ttacttcgat tttaaaatgt ccttgacttt
       61 tattttataa atgtacatat ttcttctact ggttttttag atggactctt caaattgtcc
      121 tctggcactc caagagctaa cattgcacct aaaaaatact ctcccttttc aaaaccagtt
      181 tctgcttcta aaacagcttc tatctcatct gctgcatagt tttgacttgt caaccaacaa
      241 gaaccatatc caagttcaat tgctgatagt gtaaagtttt caattgcagc acctagactc
      301 tgcatacctg gatttcttat aaataattta tctatagtct ccttaggtgc atctataagc
      361 tctaattcat aatatcctga tggattatat acctttgtaa aaactaatac taaaactgga
      421 gcttttaagt aaaatagtgt aaaattttta acaaattttc taaatctatt agccttatcc
      481 actgatactt tatccatttc tacaagtatt tcttgttgct ttttagttat cacatctgct
      541 atcttttcca ttaaatcacg gcgttttata acaacaaaat gccagttttg aatattcttg
      601 cctgatggtg ctgcacctgc tgcttttatc atttttaaaa tatcttcatc tgatacatct
      661 tgatttttaa actttcttac actttgtctt ttaaaaatag tatcttgtaa ttccattttt
      721 aaatcccccc ataacttttt tattatttta atataatttt taaactcatc ttattttaat
      781 atatcatgtt ctaacaaatc tttaaatgaa tctataaaat aatcatatac atctacattc
      841 ccaaacccat atttggcata tataaaaggt atacctacaa acttagcact atttgcatca
      901 ccttgcgtat caccaacata gattggattt attaatttat ttctttcaat tataagttta
      961 ttattttctc ctttatgcaa accagtatta ccaggacatt caaaatctat aaaatactgt
     1021 tctagtttat gtgcttttaa aaaagattct atatatccag cttgacaatt acttactata
     1081 aataatttat attttttaga tagtaattta agagtatctt ctatatcatc aaataattta
     1141 gctccatttt cagataaata gtcacattct ttcaaagaac attcattcaa taaattcatt
     1201 ctttcttctt cacttaaatt tggaaataaa cgatttgcta tttcctcaaa agaaagcccc
     1261 ataagacttc taaataaatc ttttgtgaca cttaattcta tttccttatg ctcacttaaa
     1321 acatcctgcc agactttgca tacttcttca gttgaatccc acaatgttcc atctaaatca
     1381 aaaataatac tatctaccac aaaaaatccc ccttatgtca aagtttatta tatatttata
     1441 attatatact aaaaagcaga tacaatcata aatatatttt acttgattgt atctgctcta
     1501 caatataaaa ccaattgtca aaatcaaatt ttataaattt ctaactacaa gtacacagcc
     1561 ttgctctact ttaatcttac aagaattact caacataaca tttgatattc caataggtac
     1621 agagtatttc atataataat tatcgagagg gtattctaag ccagtaagtg ttacaccctt
     1681 agcatcacca tttatagcta ttacagaaat agtgtcccct gggtttccat acaatgaaat
     1741 ttcctcattt tcaactatat acatctcttc tttatcagaa agtatcctag aatatatacc
     1801 atcttctttt aaataatata atagctttat atttgcaaga gtgtggtcaa tccttccccc
     1861 taaagcacca aaaaaatcaa tatgatttgc tttaagtgtc ttagctaaaa aaagacaaag
     1921 ctctgtatca gtctcatctt ttttagatgg aaatttttca aatttaacac ctttattttt
     1981 atagaagttt atcttttctt cttctactga atctaaatct cctaatatat aatctggcat
     2041 tatttccatt ttataagtgt gatttgcccc tccatctgca catattatgc agtcataaca
     2101 ttccttaatt ataatatctc ttgtaacttc gtaatcttca atttcgccat ttaaaacaat
     2161 acagattttc attattaaat ttaaactaat tcttcaagag aagcattctt tctaaataaa
     2221 ttaactgttt cttgaatgtc atcacttcca aatattgcag aacctgctac tattacatta
     2281 gctcctgctt gtacaacttc ggctacgttt ttagggctta taccaccatc aacttctata
     2341 tcaatgttta atccttgact atctataata gcttttaact ctttaatctt atctaaaaca
     2401 caaggaataa atgattgtcc tccaaatcca gggttaacag acattaataa taccatatct
     2461 aaatcaggta gtacatgttt aatcgtatct actggtgtag ctggattaag tactacacca
     2521 gcttttattc catgtgattt tatattttgt atagttctat gtagatgaac acaagcctcc
     2581 tggtgaacag ttattatatc acatcctgct tttacaaatt cttcaatata ctggtctgga
     2641 ttttctatca taagatgagc atcaaatacc atatttatat tttctttctt taaacttttg
     2701 actacaagtg gtcctaatgt aatgtttggt acaaagtgtc catccattac atcgatatga
     2761 agatattcac atcctgcact ttctactttt cttacatctt ctaataattt tgcaaaatct
     2821 gctgataata ttgatggtgc taatttaatc atgtttctaa tacctcctac tattattttg
     2881 tcttatttca tgtagcagct gtatataact atcatatctt tctttagata tttctccatt
     2941 tgtaacagct tcttttatag cacaattagg ttcattttca tgaatacact ttgaaccaaa
     3001 cttacaatca ttaaatttat caaattctat aaaataatct ttaagttcaa cttcctctat
     3061 atcttcaagg gcaagggaac taaaacctgg tgtatctgca accattccac caaattctaa
     3121 ttttaaaagt tcagcgtgac gagtagtatg ttttcccctt tttattttat cacttacaac
     3181 tcctgtttga agtttaaaat tttcatctat ttcatttaat aagcttgatt ttccaactcc
     3241 agatggtcct gcaaacacta ctacattttc ttttaattct tcttttactt tatctatatt
     3301 taacttagta atattgctta caggaatgac tttatagcca ctaagttcat atatattttt
     3361 aacagtttct aatgtatcat tatcatctaa atctgctttt gtaaggatta ttacagtttc
     3421 taaattttct ttttctgcca aaactataaa tctatctaaa agagataagt ttggtttagg
     3481 attttttatt gcgaatacta ttaatgcttt atctacattt gcaataggag gtcttataag
     3541 ttctgtatct ctactgtcga tttcttctaa gatacccttt ttttcatttt catcaacaat
     3601 gcttattttg actctatcac caaccaaagg tgttattttc tgctttctaa atatccctct
     3661 agccttacat tcataaatac cattataagt atctacataa taaaatccac taatcccctt
     3721 tataattttt ccttctagca tcaaatgcct ccctttataa aatttatata aacacatact
     3781 gtttatgagt agtatatcgt gttattcttt cctattttta tataatacca catttttttt
     3841 aaataacaaa tcctccgttt ggactaatta cctgaccagt gataaaattt gatttgtctg
     3901 atgccaagaa aatagcacaa tttgctatat cttctggagt tcctagcctc attagagggg
     3961 tttcttccac aagagcgtct atatcttcct cattatatcc agataacatg tcagtattaa
     4021 tgacacctgg agctatgcta tttactctaa tatttgatgg tcctacttct ttagctaatg
     4081 cctttgtcat acctattatg cctgcttttg ttatagaata atgcacttca caagacgcac
     4141 ctgatatacc ccagattgaa gatatattaa ttatatttcc ttttttttct gatatcatgt
     4201 attttaaagc aacttgtgaa caataaaagc ttccttttaa attaatattc atcatattat
     4261 cccaatcttc atcagttata tctgtaaaca acttatcttg acttacacca gcattgttta
     4321 caagtacatc caatcctcca aattctttta tacaataatc taccatatcc tctacatctt
     4381 ctctatttga aatatcagcc ttaaaaagtt ttacagaaaa atttttttca tttaatatag
     4441 tgtacaactc tttagcttca ttttctgact tattaaaatt tactaataca ttgtaacctt
     4501 cttttgcaaa agctttagac atagctttac caatccctct agctcctcct gtaattaaaa
     4561 ctgttttctt cttcataaat acttttctcc ttatattata accaattcag tattttatac
     4621 aaaacaaact gccctttaaa gaaaatattt tctataaaag gacagctctt attttattaa
     4681 tatttattct gttttaccaa tgtttgcgcc agttcctgat gaagttcctc cattatctcc
     4741 tgagtttgag cctcctgaac tatctccatt gtctcctgag tttgaacctc ctgaacttcc
     4801 tccattgtct cctgagtttg agcctcctga acttcctcca ttatctcctg agtttgagcc
     4861 tcctgagttt ccaccactat ttcctgagtt tgaacctcct gagttacttc cattattgcc
     4921 tgagtttcca ccactatttc ctgaatttga gcctcctgaa tttccaccac tgtttcctga
     4981 gtttgaacca ggttctgttg gtgtattatt ctctggtgtt gttggttttt tatctggtac
     5041 tgttggagtc tgtgtatttg atttttctga acctttgctt acatataggt ttacctcatc
     5101 accttcctga gctcttgatg agccagcacc cggactctga cttaaaactg taccttcttt
     5161 atatattgag ctgtattcat acttaacagt tcccactttt aagttatttt cttcaataag
     5221 ttgttttgca ttactcaaag taagtcccac tacattagga acagatgcct gacttgaacc
     5281 tttacttacg acaacattta tagtatcacc ctttttgaca tttgtacttc caccttcagg
     5341 tgtctgtgat attatacaat tttcatcaac ttcactatta tactcttcac tttttacact
     5401 caggtataat ccttcttttt caacagcact ttgagcttct tctaatgtca tatttacaag
     5461 attaggaaca gtcaaagatt tattgccaaa ccctccagca aataaaaact tatatgctaa
     5521 gaatacttga gcacacaata tcagtatcaa aacagccgca attactttta atcttcttct
     5581 agattttggg ctttcctgtt ttttcttctt tttcttagtt ctcttacttg gagtactctt
     5641 aggtctctga ttctttttag ctctcattat ctcttcctct tcttcatctt catcatcatc
     5701 ttcttcataa aaatcatcat agtaatcttc atcatcatcc aaatcagcta cttcaacagg
     5761 cttaaccact ttttcaggag ctggttttgc aagtgttgga tttacaactt tattaatttc
     5821 tttttcatca attttcttag ttgcaaaatc atcatattct tttataaaat ctaaatcaat
     5881 atttttttct atatactcta tatcttctat caattcttca gcagtttgat atctatctgc
     5941 actagatttt tctgtaagct tttttattgt agttcttaca ctttgaggaa tcctaacttt
     6001 ttcttctgat gtaaagtcta tatcatcatt aatgtgttga agtgctatag aaattggact
     6061 atctccccta aatggaactt ttcctatcaa catttcatat aaaactatac ctagagaata
     6121 caggtcagca ttattagtta caaatttacc tttagcttgc tctggtgaaa aataatgcac
     6181 tgaacctatt atactaccaa tattagtcat tgttgaattt gaaacagctt tggctatacc
     6241 aaaatcagcc acttttacta ctcttccttc atttgatatg agaatattat gaggttttat
     6301 atctctatgt ataatcccct ttttgtgcgc tgcactaagt gccatagcta tttgttttgt
     6361 tatatctaat gcagtatatt catctaatat accttcatct tgtataatct cttttagatt
     6421 cttcccatct acaaactcca ttacaatgta gtgaactttt ccatcttcac caacatcata
     6481 aacatttact atatttggat gtgaaagact tgctactgct tctgcctctc ttttaaactt
     6541 tgttagaaat tcatcatcat ctacaaattc aggtctaagt actttaagtg caacagtcct
     6601 gtttaataat ctgtctttag cctcatatac aaaggccatt cctccatcac caatcttcct
     6661 gatgatttca tatcgatttc ctaaaattgt atctcccaca atatcaccgt cctaattata
     6721 cttttatcac tataaccgaa acattatctt taccagaaac atcattggcc atacttatca
     6781 attcttcact tatattacta gttctctcat attcataatc taatattaaa tctcttatat
     6841 cttcatcatc aataaaccca gttaatccat ctgtcgcaag aagtattata tcactttttt
     6901 tgatttcttt cttaaaaata tctacaacaa ccatatcatc tgttccaatt gctctagtta
     6961 ttctattcct ctgtggatgt cttcttgcct cttcttctgt aatgacatgg gccatcataa
     7021 gttcttcaac cacggaatgg tctatagtta ttttatcaaa tttttcatct gttaacaaat
     7081 aacatctgct atctccaaca tttgccacat ataagacatt attatacact atagccgtaa
     7141 ctaatgtagt tcccattcct tcaaattcta tatcttccat agattttttg tgcacaattg
     7201 agtttacatt attataagcc tgttttaata tatcatctat atagtctatt tttacattat
     7261 catgttgtaa taagttttct tttagaaaat caattatatt ttctactgct aatttactgg
     7321 cgacttcacc ttttttatgt ccacccattc catcagctat ggcaaatatt cctattggac
     7381 catgttctgt atctataact tctccctcac aatagtcttc attgtttttt cttatttttc
     7441 ctatatggga ggcacaacta taaaccatac gacttcctcc ttacaaatta cttgtatttt
     7501 cttctcaatt gcccacaagc tccactaata tcagaaccca tagacatcct aactgtggca
     7561 ggtatattgt tcttctccaa actatcccta aatttataaa taaatgcttt atctggtttt
     7621 tcgtattctc tttcttcaac tttatttatt ggaattaaat ttacatgaca tagcatacct
     7681 tttaggagct tagctaatgc ctttgcttct ttttctgagt catttactcc ttttataaga
     7741 gaatattcaa atgtaaccct tctatttgtc ttttttatat aatatctaca tgcattcaat
     7801 atttcttcaa tagaataagc atttgctaca ggcataattt ttcttcgttc ttcatcatat
     7861 ggtgaatgaa gtgataaagc taaatttata gctatttcta agtctgccaa ctcatacatt
     7921 ttaggtacta ttccacaagt tgaaagagtt atatgtctat accctatatt aagaccattt
     7981 ttttcgttaa ttatttttaa aaattgtttt gtattttcaa agttatcaag tggctcacca
     8041 ctccccatca atacaagatt tgataccctc ttaccagtat cttcttgaat tttaataact
     8101 tggtctaaaa tttcccatgg ctctaagttt ctaattaatc catccattgt agatgcacaa
     8161 aaattacatc ccatcctaca acctacttgg ttagaaacac agacagtaac tctactatca
     8221 taatccatca tcacagtttc tattatattt ccatcatcta ataaaaacaa atattttttt
     8281 gtattatcta ccttagattc taactttaat tctatatcta tatgccctat acatgaaacc
     8341 tcttctaatt tatttctcaa actttttggt atattgttca tatcatcaaa agtttttgca
     8401 cccttatata tccaagagaa tatttgactt cctctaaagg gcttttcatc tatagttttc
     8461 ataaactctt taagttcatc ttcagtaaaa ttttttaata ctatcttttt cttttccatt
     8521 ctctcactac cttattctct ttaattttgc tatgaaaaaa ccatctatac catgaatatt
     8581 aggatatatc tttaaatatc ctttatcttg attgtctaag tctacattta ctgtatcaat
     8641 tggaacaaat tcaaagttgt gattttcttc aacaaaagaa gtaactatat ttatattctc
     8701 cacatcttga attgtacatg tactatatac taaagttcca ccaactttga catatttaga
     8761 tgcattttct aaaattttct tttgtataga agtgatgtct tttaactctt cttctttctt
     8821 atacttaatt tctggtttac gtcttattat accaaaacca gagcaaggaa catctgctaa
     8881 aacataatca aatttactta tactattttc atcaatctca gaagcatcaa atctttctac
     8941 aaacacattt ttaagcccca atctatttac agtagagttt ataagcttta gtttatgctc
     9001 aaaaatatct ctagctacta cttgaccagt attgttcatt aaagtagcta agtgagtaga
     9061 tttccctcca ggagcactac atacatccaa aacaaatgaa ccttcttttg gattaattac
     9121 tttccctact atcatagaac ttatatcttg aattgtaaat aaaccagcct taaataattc
     9181 atttttttct atatttttca ttttttcgac tttaatagct tcttctacca taggaacttt
     9241 taaacataca atacccattt cacttaattt ttcaataagt tcttctctac ttattttaag
     9301 tgtattcgtt cttatataga tactaggctt ttcattattt gcttccaaca aatcttcagc
     9361 aaattcttgt ccaaatttat ctatccagtt ttttataatc caagagttat aggaatactt
     9421 tatagataag tattttacac tatcttcctc agttatgtcc attatagtct ctttagctct
     9481 tatttcattt ctaagaatag catttatgaa accagaagat tttttatcat atttcttaga
     9541 taattttaca gtttcattaa ctgctgcata atctgatata ctatctaaaa ataaaatctg
     9601 atatgttccc attcttaaaa agattttaac ataagttgac atttttttta cctttatttt
     9661 tgaaagttta ttgattatat aatctaaata atatttattt tctattactc cataaattaa
     9721 ctctgttgca agtcctctat ccatatcact tatttctaaa tttttaaaat gcttatttat
     9781 tgcaatattt gaataattgt catttttttc tatatcacat aatactttaa atccaacttc
     9841 tcttgcatcc atataaattt ctccctttta ttaaacataa aaaagggttg tttctaaaca
     9901 acccacttta cttttagtca tttcttcttt gagctattag taacaatcta agtaattgaa
     9961 gtattgaaac caatgctgct gcaacatatg ttaaagctgc tgctgaaagt actcttctac
    10021 tttgtcttga ctcactttca tctataatcc ctaaattccc aagttgaacg attgctctac
    10081 ttgaagcatt aaattctaca ggcaatgtta ttatttggaa taacactgaa gccgaaaaca
    10141 atagtatacc aatttttaaa aatggaccag ccataataaa tcctaaaaat attaaaaacc
    10201 aagatatact tgaagcaaaa ttcactactg gtactaaact acttcttatt tgaagaggtg
    10261 cataaccttt agcatgttgt atggcatgac cacactcatg tgcagctact gcaacagaag
    10321 ttatagatgt tccataatat acatcttctg acaaccttac agcctttctt cttgggtcat
    10381 aatggtcact tagatgccct ctaaccattt ctatctttac atcatacaaa ccatttgaat
    10441 caagtactct tcttgctgtt tgctctccag tatatcctcg acgtgtattt actcttaaat
    10501 acttatttgt tgttgaactc actttaaatt gtgcatatat agtaagtaat atagctggaa
    10561 ttaatacaac cattgttggg tcaaatcccc aaaaaccgcc atatacaggg tacataaata
    10621 acactctcct aaaatatatt tttattatac atcctcttaa tattcacttc acttaaaaac
    10681 agtttaatta caaactaata tattttttcc tgttaaaaag cctatagctt tttcaatatc
    10741 cataatgtct acattagtat ttacacaagg tccattaggt cttttgttaa atacacctaa
    10801 aacaggaatt ttcttaatat cttgtattcc agatgtcaaa tctctttcac atgcaacagc
    10861 tacaacagct ttaggtttat tatccattat aatttttcta gctagggttc ctccagtagc
    10921 tacaaatatt tttacattag ttttttcctt tagcttaatt aattctccta tgttgcatct
    10981 tccacattct ttacaattat ctatatcatt agtaactttt aatttacaac tattctcttg
    11041 aatacaatga ggtattaaaa ttattatatc ctctggatta aaattatatt tattactgta
    11101 tatatattca ttatttaact ttatatatat tcttctaata tcactttttg acataccaaa
    11161 tgatgatgca atgaaagata taataggaaa taatccactg acaatattaa aatttatttt
    11221 cattatattt gagttaacat actttccttt aattactcta taagtaactg ctgttgaaca
    11281 tagtattata agtattagtg atattattat aatatttatc atcaaggaga atatttgagt
    11341 taaacttatt ataaaaaaat taacaactcc tatcaaaatt cctaatatta aaatcaaaat
    11401 cccaacactt gttaaatact tctttatatc tgtcatactt ttcacctaac ccaatactaa
    11461 accagtttct atagtattcc cttttatata ttcaccaacc aacattctct ttttattcgg
    11521 catctgaatt tcttcaatta aaagtacatt atctatagta cttactttta tcccatcttt
    11581 gcttacatca attattgtac ctacatcttt tgtgcttttt tcatctaaca ctttagtttt
    11641 ccaaactttc attatgacat cattataggt agtataggca cttggccatg gatttactcc
    11701 tctaactaaa ttgtgtattt ctctggcact ttttgaaaaa tctatgttac ctaatgattt
    11761 attcattatt ggcgcatagg aaaattcttc atgattttgt acttctcttg gagcatttcc
    11821 ttcttcaatt aatcttaatg tttcttttaa agtttctgcg cctatattca tcattttatc
    11881 atgaagttct cctgctgtta tattttcatc aagatttact tctgtcttta gtatcatatc
    11941 tccagtatct agcccttcat ccatatacat agttgtaaca ccagtctttt cttcaccatt
    12001 tattattacc caatttatag gtgccgcacc tctatatttt ggaagtaaag aaacatgaac
    12061 atttatacat ccaagtttag gaatctctaa tatttctttt ggaagtatct gtccaaaagc
    12121 tacaactact attacatctg gatttaaaga tttaatttta tctataaatt ctttatctct
    12181 agcctttact ggttgatata caggtatatt attttcaatt gccagttctt ttactggact
    12241 catacctagt tttttacctc ttccttttgg tttatctggt tgagttacaa cacccaatat
    12301 ttcatacttc tcatctatta ttttttgtaa acatggaact gctatatcag gagttcccat
    12361 aaatactatt ttcatcaaat caactcctac tacttttcta ttttgtcaac aaacaaaatt
    12421 ccatctaagt ggtctatctc atgacaaaat gctctagcta aaagttcttc tccctctaac
    12481 tctattgttt caccatttct atttaaagct ctgaccttta cataatttgg tcttctaaca
    12541 tttcccgctt ctccaacaac acttaaacat ccttcctcat ctatttgctc cccagatgtt
    12601 tctattattt caggatttat aagttctata agctcttctc caatatctat tactactact
    12661 ctttttaata ttccaacttg aggtgcagcc agtccaacac catctgcatc atacatagtt
    12721 tctgccatat catctaataa ttgtattatc ttttcatcaa ttttttcaac cttttttgat
    12781 ttttttctta atactggttc tcctatttga actatttgtc ttaaagccat tataattcct
    12841 cctaaattta taatacactg tttggattaa tatctataga tacattgata ttcttatcaa
    12901 atatcaaatc tcgttttgtt atacatatat attttattat accctttaag agattaattt
    12961 caatattttc atctttaaag agtatttgcc atctataatt ttgatttatt tttgatattg
    13021 aacatggatt tggacctaat ataaatccta aatcatttat accccttttt tctaataaat
    13081 aaatcaatga tgcatgcata ttttttatat tttttatcac tagtctttca tcttcaccac
    13141 taacaactac acttaacata ttattaaaag gagaatatcc aaatgctttt cttattttta
    13201 tctcatcttc ataaaaaccc tcataatcat attcaatagc atgcttaata gcatagtgtt
    13261 cagtgtcata agtctgaagt actacttttc cctctttatc agctctccct gctcttccag
    13321 agacttgagt tatcaattga aatgtagttt caaaactttt aaagtctgga aaatttaata
    13381 tcatgtctgc agacaaaata cctactaaag ttacattctc aaaatccagc cctttactta
    13441 acatctgtgt tccaataagt acatctgctt ctttatcttt aaatttattt agtatctcat
    13501 ctaaagcacc tttttttgaa gttgtatctt tatccattct caaagttttt atatctggaa
    13561 aaatatattt taattcctct tcaatttttt gagttccaac tccaaatggc ttaacataag
    13621 tacttttaca ttcaggacac tcttttggaa tttctttctc atatccacaa tagtggcatc
    13681 ttccagtatt gcttttctta tgataagtta aagatatatc acaattttca cattgaaaca
    13741 catatccaca ctttctacaa gatacaaaat ttgcataacc tcttctgttt aaaaatagta
    13801 ttacttgatt attttcttca atcgcataac gtatttcttt ttgtaatttc aaactaaata
    13861 tacttctatt tcctttatct aactcatctt tcatgtctac cacttcaatg tttggaagag
    13921 gcttatcatt tgctctactt tttatattta taagtttgta ttctccagat tttgccctat
    13981 aatactcttc aattgagggc gttgctgaac ctaaaataag agttatatta ttttttaatg
    14041 ccataaatct agcaacttct atagcattaa attttggatt cttctcagac ttatatgatg
    14101 actcatgaca ttcatcaatt attattaagc ctaaggaatt aaaaggtgca aataaagctg
    14161 acctagctcc aattaacact cttactttac ctgctttgac agctttgtaa acatcatgtt
    14221 tttctccttc agatagttta ctgtggaaca ctccaaccaa atctccaaac ctactcttta
    14281 gcctatctat tgtttgagga gttaatgcta tctcaggtac taagaatata ctgtctaagc
    14341 cttgatttag agcaaattct attatttcca tgtaaacttc agtttttcca cttccagtta
    14401 ctccatgaat taagtatggt tttttatcat ctacaaacat attcgacttt atctcatcaa
    14461 ctgcttcttg ttgctcattg tttaatttta tactttttag tacggatttg taaatacttt
    14521 ttggctctct ataataatcc ttaaattcta gggttattag ctttttctta cttagagaat
    14581 ttatactttg ttttgaagca tttaataaat ccaataaatc atttatctct acattttcat
    14641 tatttttaag aaaacttaat atctcttttt gtttacttcc cacatttatt ttattttgct
    14701 ctatataatc gtcaatctta tcactttcta aactcaaaga tatataacat accttctttt
    14761 catttttgtg atttttatat tcccaacata attttataat tccattctta ttcattgtgt
    14821 acaaagaact atttaagttt ggtatatatt ttaacttatc aaccttaatt ttacctttac
    14881 tatcaatcac tttctctact atttctctat ttttatcact taaagttgat attttttcct
    14941 tcaattcaat atcatttaat ccacttaaac tttcacctaa taggactact ttataattat
    15001 ttaatttgta tccctttgga tatatcaaat ttatacattc tatataagta cacaaatatc
    15061 tatttttcat ccaataaacc aactctaaat cttcttttct aaatatcgga ttttcatcta
    15121 atatatcaat aatttctttt atttttattt tttcatctaa gctatctgta aattgaaata
    15181 caaaggcttc tgttggttta ttaccttttc caaatggtac taatattctg tgcccaattt
    15241 ttattacatc agataaaaat acaggaattt gatatgtaaa taaattatct gtatatatag
    15301 tattacttct aactattacc tttgcatatt ttttcattat aaaacctcta cttaaattta
    15361 atatattgtt catattttaa tatactttac aagatattaa aatctcagaa tttataagca
    15421 atttcaagtt attaatatta actttatttt aataattaac tattaattat attttatact
    15481 ttatgacaaa ataaatgctg aaaactacaa tttaactgac atttgcgagt ttttactcgc
    15541 taaaattaaa ttgcagcttt cagccacttt agctgtgata aaatacacaa atatcatatt
    15601 taaaaaaggt cttatttctc aagcaacgct ttaactttat ctaaaataac attggctact
    15661 tcttcttttt tcatcttagg atactcagta atatttccct ctacatctat tatttttaca
    15721 atattagtat cagctctaaa accagcacct tctttagtta aatcatttgc cacaataaaa
    15781 tctaaatttt tcttttttat ttttcctttg gcatgttcta taaggtcatt agtttcagct
    15841 gcaaatccaa ttagtatctt atcttctttt atttttccta tttcataagc aatatcataa
    15901 tttctactta gttctattga taaatcatca ttcttctttt taattttttt gtcagaataa
    15961 gtttttggtt tataatctgc aactgctgca ctttgaatta ctattttatt ttcacttaaa
    16021 tttgatacta ctgcttcata caaatcttgt gctgactcta tttgaacaaa ttttttaaga
    16081 ttttgtggaa tagaaagatt tgtaggacct gatattaatg ttacatcagc acctctagct
    16141 atagcttctc ttgctataga atatcccatt ttaccagaag acctattagt taaatatctt
    16201 actgggtcta tactctctac agttggacca gctgtaacta tcatactttg accttttaaa
    16261 tcttgctctt tagtaagatt agtcaaaact tcctctacta ttatatctgg attagctagt
    16321 ttacctgttc caatatctcc acatgcaagc cttccacttt ccggttcaat aaatttatat
    16381 ccaaagctct ttaaagtttg tatatttttt tgaacaattg gattttcata catattagta
    16441 ttcatagctg gtgctataag aacctgtgct tttgttgcca taacagtagt tgtcaacata
    16501 tcgtcagcta taccatttgc aatcttgcct ataacatttg cacttgctgg cactattaag
    16561 aataaatctg ctttttttgc taatgatata tgttcaactt cccaagtttt tggttcttca
    16621 aacatatctt ctactacata attttgactc agcgattgaa atgtaagtgg tttaacaaat
    16681 tctgttgctg attttgtcat tataacatgg atatttgcat ttagtttttt taacttactt
    16741 acaacatcac aagccttata tgcagctata ccgccactta tgccaattac aacagtttta
    16801 tcttttagca tgaccttact cctcttctga aatttgttgg tgttgctcag catgatgtct
    16861 agcttcttct atctctattt cctcttctgt caataatcta tatgttattt ttccacttgc
    16921 aacttcttta gttgctacac atacaggctt ttccttagtt ttatttgaaa catatggttc
    16981 ttctccatca attaattttc ttgctctctt tgaaacagtc cctactaaat agtatctgtt
    17041 gtctattttt tctagtacct cattgataga tggttttaac ataattataa ttcctcctta
    17101 aatttctcta ttataatatt tttatatctg ctaactttat tcttttcaga tgatattata
    17161 ccttctattt ctttagcaga tgtttttaca tcttcattaa atataaaata atcataatcc
    17221 ttaatcattt taatttcttc atatgcacag ctaaatctct tctctatttc agcttctgtt
    17281 tctgtacctc ttccaacaat tctatttttt aattctttaa gtgatggtgg tagtacaaat
    17341 ataaatactc cctctgggca aacttctttt atttgttttg ctccttgcat ttcaatctcc
    17401 agtaatacat cttgtccttt ttctaaacat tccattattg ccgcttttgg agttccataa
    17461 aaattatcat aaatttgagc atactccaaa aactcacctt tttctatcat ctcttcaaac
    17521 ttttccttac ttatgaagaa ataatttact ccatcaactt ctccagttct gggttttctt
    17581 gtagtagctg atacagaaag ttttattgta tcattttctt taagtagttc tttgcaaata
    17641 gtaccttttc ctgcacctga tggtcctgat acaactagca ataatccttt tttcacaaac
    17701 atttaagcat tccccttcta atattgtatt cttactctat attttgtatt tgttctctta
    17761 ttttttccaa ttcgcttttt acttctacta ctaaattagt tatatttata tcagatgact
    17821 tcgaacctat agtgttagtt tctctattca tctcttgtat taagaaatct atttttctac
    17881 ctatagagtc gtctttaaat atagtatttt taagttgccc tatatgactt ttaaatctaa
    17941 ctatttcttc tgttatactg cttttatctg catatattgc aacttcttgt gctaatctat
    18001 tctcatctat tatacttggg tcatccagta attcacttat tctcaaattc aatttttctc
    18061 tataatcttc tacaacacta cttgaatatt tttcaatctc ttctatatga ttttttaata
    18121 aatcacatct catggcaata tcttcagcta attttttacc ttcttcactt ctcatttctc
    18181 ttaatttgat taatgcatct tcaactgctt gattcaacat tgaccacaat aaatcttcat
    18241 cttcttcctt ttcttctatt ttcacaatat caggaaactt tgcaacattc ataacgctaa
    18301 tatcatctat aatatcaaat ttatttttta tttcttttag tatgtctata tactgagatg
    18361 ctaatccctc atcaaaattt aagtttacat cttctttgcc taataagtca aactttatgt
    18421 ataaatctac tcttcctctt tttacataat tttttactaa atttctaact ttatcctcta
    18481 aaaatgaaat ttttcttgga agacgtatgt ttatatctga atacttatga tttatcgttt
    18541 tacactctac taaaaagtaa taattatcat ccttgtattc tcctcttcca aaaccagtca
    18601 tacttatagc cattaattaa acctccaaaa taccttcaca tatttttact gctggacctg
    18661 tcatataaga gaaatctcct acatctattt taactgttcc accttgagac gttacattta
    18721 cactactttc taccatatta agtaaattgc acactattgc tgatgcagtc ataccagtac
    18781 cacaacctaa agtatatcca caacctcttt cccaagtata aacatgtata ttatacttat
    18841 cttctacctt tacaaaattt acattcgttt tttcaggaaa tattttatta ttttcaatct
    18901 cttttccata tttacaaaca tcatctacat ctaattcatc tactataact actgtatgag
    18961 gaacccccat caacatagaa gtaactttaa gctccctatc taaaaccttt atactttctt
    19021 gcacaaaacg ttctttattt gtaagtacag gaacgtcctt agctataaaa cttccttttc
    19081 ccatattgac tcttatagag tttatttctc tattagtaag atttactttt atatctttta
    19141 taccatctaa tgtatctact gtaaaacttt cttttttaac tatacaatta tcataaacaa
    19201 atttacaaaa acatctaagg ccatttccac acatagctgc tcttgaacca tcagaattat
    19261 aatataccat ttctacatct gcaacttttg aatctttcac aactaacaat ccatccgctc
    19321 ctacagaaaa tcttctatgg catacttttt ttgctaaagc agtataatca gatggattta
    19381 tctggtcgaa tcttccatct attgctataa aatcatttcc tattccatgt agtttccaaa
    19441 atttcataag tatcgctcct tcgtaaatta acacttaaac tattataaca taaaaaaatt
    19501 cccataaact tataatttat gggaaaagtt ttgtaatgac aactataatt tgaggatgtg
    19561 agggagagtt gccattacaa ttagggtaat tatattatgt ttttaagcta gttctttcta
    19621 tgtttatata ttaatatttc tatatgaatt ttatgtatgt tttatttaaa ctgtctatga
    19681 attttttaat taaacatctg gtaactagct ataatccttc tagtagatat ctattaacat
    19741 acacctatta attctttaag tgtttttaaa acatagtcta aatcttcctt agtaatatct
    19801 acatgagtta caaatctata ttcaccattt tccattttat taatttttat atttctttca
    19861 aaaaattctt ttattaaaac atcctctttt ataatatctt cactcatctt aaaaaatacc
    19921 atacttatat ctggattaac attgtttact tcaatgccat caattttatt taattcacaa
    19981 gctaaatatt ttgcattttc atggtcttca ttcaatctta aagtcatttt ttcaatggca
    20041 attataccag ctgctgcaac tatacctact tgtctcattc ctccacccat aactttttgc
    20101 tttcttctag cttttgctat aaattcttta tttccagcaa gtatagaacc cattggtgca
    20161 gctaaacctt ttgacacaca gaacataaca ctatcacaac actttgctat ttctttagct
    20221 tctacaccca aagttaatgc tgcgttaaat aatcttgctc catctaaatg tactggtaag
    20281 ttatgtttct cagctatttt tttaatttct cttaaattat caagactcac aactgttcca
    20341 cctgaatatg cattttctac acatataagc cctgtctgtg gttcatgtat gtcatctctt
    20401 ctaattgcct tttcaacaag ttcaggattt agagctccac tttcgtcttc atctatagtt
    20461 ctaagctgaa ctccagctat tacagcaggt gccccaacct catgagtcac aatgtgataa
    20521 cctttaccaa taattatttc ttgccctctt aggcaatgag taaatagagc taattgattc
    20581 ccaaaagttc cacttggaag gaaaatagca tcttcttttc caactttagc tgctgctaat
    20641 tcttcaagtt tatttacagt agggtcatct ctaaagattg aatctccaac aggagccttt
    20701 gccatagctt ctctcatttc gtcagtaggc atagtaacag tatcacttct taaatcgata
    20761 aatctcattt tttcaacctt ctttcatatt tatatactat agaaccttaa aattgatttt
    20821 ttctgtaaag ttcatatact ttcatagctt atactctaca caataattat actatattta
    20881 ctttatattt aatctacttt aaattattaa ttttaaaaat aaagtttcct ctctaataaa
    20941 tataaataat tatacaattt aaatattaat ctctattgtt taaattcccc ctagtcacaa
    21001 agcgtatatt atgtgtataa ttaatttact gactcatttt ggtcaaagaa aggggtgcta
    21061 taaatggcat tagatggatt agttatacat tcaatagtcg atgaattatc atcaaaactt
    21121 acaggtggaa aaatagataa gatacatcaa cctgaagatg atgaggtaat ttttaatata
    21181 agaaataata aagaaaattt tagattggtt ttaagtgcaa gtgcctcaaa tcctagagtt
    21241 tatcttacaa gtaattatca aaaagaaaac cctctaaaag cgcctatgtt ttgtatgtta
    21301 cttagaaaat acatacaagg tggaaatata gtagaaattt ctcaaatagg ttttgaaaga
    21361 ataataaaaa taagtgttga atctttagat gaattaaaag aaaagacagt taaaaatatt
    21421 atgattgaaa ttatgggaag acatagcaac ataataataa ctcatggtga agaaaataaa
    21481 attatagatt ctataaaaag agtccctttt agcataagta gagttcgtca agttttacct
    21541 ggtcatgatt attcattgcc accagaacaa aacaaactca accctcttga tgatatatct
    21601 aaggatttgt ttattaaaaa cctagaggaa ttggaaggac ctatctttaa gtctatatat
    21661 tctaaatttc taggtataag ccctattata gctaaagaaa tttgctacag agcaggtgta
    21721 aatcaaaatg ctatcataaa ggatatatct gatgaacaat ttgattcttt acacaaagta
    21781 ttttgtaatt tattcaatga tataaattct aacaaatact ctccttgcat tattatagat
    21841 aaaaaggtgg ataaggtagt tgatttcagt tgtataaacc ttacattatt tagcgattta
    21901 tcatatataa ataaggatag tatgtctcgt attctggaag atttctatag aactaaggat
    21961 attaaagata gaattaatca acgttcatct gatttaaaga agagtatatc tgttaagctt
    22021 gatagacttt ataataaact taaaaaacaa gaagaagaat tatcagaatc cgaaaatgca
    22081 gacatttata agataaaagg agaattgatt acttcatata tttatatggt agaaaaaggt
    22141 atggaaagta ttgaagttgc taacttctat gatgaaaatt gtaatgatgt aacaatagaa
    22201 ttaaataaaa acttgacacc atctgaaaat gctcaaaaat actttaaaaa gtataacaaa
    22261 atgaaacatg ctaaagtcga gatatctcat caaatttcct taaataagga agaaatagat
    22321 tacttagaaa acataatttt aagtattgaa aactgtgaaa atttagctga attacaagat
    22381 ataaaagaag aacttgctaa ggttggatac atcaagactc aaaagaaaaa cagtaaaaag
    22441 gatactatcc catctacaaa acctcatgaa tttgtttctt ctgatggatt taaaatattg
    22501 gttggtaaaa acaataagca aaatgactat cttacactaa gacttgctga taatgatgac
    22561 ttatggatgc atacaaagaa tattcctggt tctcatgtaa taataaagtg tgctggtaag
    22621 gaagtccctg ataatactgt atttgaagga gctatgctag cagcattctt tagtaagtca
    22681 aaactttctt ctcaggtgcc tgtagactat actaagagaa aaaatgtgaa aaaacctagt
    22741 ggttctaaac caggtatggt tatttatgaa actaacagta ctatttatgt tactcctgaa
    22801 gaagaaacag tagccaagct taaggttaaa tctgaataaa ttctgcacta aatacaaaat
    22861 aaatgttaga caactacaca ttatcattct aaataaaaat agtggccttc ttataaagta
    22921 caataataag gccactttct aattagctta cttttaattt tctaacaaaa tacttttctg
    22981 ttttaataac tatacttata ttcccaacaa atattttcag tcttcttata tagatgtaat
    23041 taaaaagtta acactaaaag ctatttttta atttattgat ttgttttagt aattcattat
    23101 attctgattc atacaattct ttttttagat tatctttttc tatagataac atagatataa
    23161 cagttgtaag tctattttct aatactagaa gattttcttt tttgatttgg ttttctctac
    23221 taggagtttt tttatttctg ctaattgtat attcgtcata attacaatca aactccctta
    23281 ttttagcatc ttttatctct ataatatagt tacaaatatg tgatacaaat actctatcat
    23341 gagacactat aagcatagtt ttatcagtat ttatcagtgc cttttccagt gcttccatag
    23401 attttatatc taagtaattt gttggttcat caaatactaa aaaattatta tcttccaata
    23461 ttattttaca tagtgctatt tttacctttt ctccaccact aagtactttt acttttttgt
    23521 agacatcatc acctttaaac ccaaataggc ttaagtttat ccttataaaa gattcatcaa
    23581 atgaactatt aactttagta ttgtatagaa cactcttttc ctcatctaat aaactttgat
    23641 tttggtcaaa ataacctact tttaccttgt tatttatttt tatattgtca tttttatcag
    23701 ccaatatttc ttttatcaga gtactttttc cacacccatt atcacctaat aatgctatct
    23761 ttttacctct ttttatctta aaggaaacat tatctaacag gagcttattt tctaacttta
    23821 gagtcatatc ttttacctct actagatttt tactaattat ctccatacca tcttgaatct
    23881 taatgttcat ttctttagaa actttaggtt tattctttac ctcaagttta tcaattctgc
    23941 tttttatagc cttcacattt gagtccaact ttttcttatt agtctgacca cccattttgt
    24001 gcaacctagc ttctgaatta cccattcttt ttggtgtttt tcttatgcca tcacttaaag
    24061 cttttttata taaaagagct ttttcaagcc tttttttctc tttaacatat tcttgatact
    24121 caaaatcagc tctttttact tcttcatctt tttgcattaa ataatcagtg taattgcctt
    24181 tgtaagcttt tagttttcca tcttctagtt ctaatatagt tgtacataac tcatccagaa
    24241 aacgtctatc atgagatatt aataataatg ctccctcatg ccttttaaac atatcttcca
    24301 aaaccccaat gcttttttta tctaagtttg aagttggctc atcagctatt atgatatttt
    24361 tcttattact cagcgcatct gctattttta acttaacctt ttcccctcct gataagtgtt
    24421 cttcaaattt atctggagca tttaaaagac tcttctcctt actatgacta catgtttcaa
    24481 tattattttc actctgactt atataagaat agctttctgt aaggtaagta tatccttcat
    24541 caatttctat ttctcccaat attgctttta ataatgttgt ttttccttga ccatttgaac
    24601 caactagacc tattttgtca ttttctaata tttcaagttt atctatatcc aaaattaatt
    24661 tatctgcata atatttcttt aaattctcta cttttactaa caacataaaa aatccctcct
    24721 taacacactt aaatataagg agagattcta taaataggca taacaaataa acgtatagac
    24781 tataatctac tctccttaat ttaagcattg caaataaagc caccaaaata ggcttttcaa
    24841 aaattacaat actttaaatt ataaaaaata gattatattc tcattgtcct agttaccttg
    24901 ccctttcttt catttatttt taatcattat atcaacatta attacaaatg tctatagaaa
    24961 attaactaat tttagttatt caatatacaa cttattcttt aaatttattc ttcttcaact
    25021 ttaaagtcct gattatttaa aattctgttt aatacaattc caacaattgc agctaaacta
    25081 agaccagtta tctttactgt acttgttata gggattccaa cagaaatacc tttattagat
    25141 aaatatgttg ttccaagacc tattaataat ataactgcta tgattaatat atttatttta
    25201 ctttctacac aagaactgtc ccttatagtt tttaatccta cataagttat catcgaaaat
    25261 agcattatac taattccacc cataactgaa cctggtatac tttgaagaaa tccaccaaac
    25321 ttgcctacac atgcaagcaa tatagcaaat attgctgtac gtctaagtat tgaagggtca
    25381 tagtttttag ttatagcaag tactgctgta ttttctccat aagttgtatt tgctggtcct
    25441 cctaaacacc ctgcaactat agtcgcaaat ccatccccaa gtaatgttct atttaatcca
    25501 ggattttcta taaagttttt acctactaca gcaccattag tagtcatatc tcctatatgt
    25561 tccataaata cagctaatac aactggagat ataatcacta ttgctcctaa actgaactta
    25621 ggaactgtaa agttaggtat tgcaaataaa cttgcttctg taatagtagt tatatctact
    25681 aatcttaata tcaaacagat tatataccca gaaaaaactg ctattaatat tcctaattgt
    25741 tttataaatc ctctaccaaa cttattggtt aaaattgcta ttgctaaagt tataaatgct
    25801 atcacaaaat tggctgaagc catactaaaa gctgttggca ataaatttaa tcctataact
    25861 actatcatag ctcctgtaac ttgtgcagga aaatataatt taattttatt tacaccaact
    25921 acttttacta taatcgacat tataatataa attaatcctg ctactattat accaccttga
    25981 gcatatgcta aatctccacc atacgcctct ttagctgcta gtataactgg tataaacgca
    26041 aaacttgaac ctaaaaaggc aggtactttt ccttctgtac aaaaatgaaa tatcaatgta
    26101 ccaacaccag cacagaaaat tgcaactgac ggattaaaac ctgtcaaaat gggaactaat
    26161 actgtcgctc caaacatggc taatagatgt tgtaaagaca ttatcgtttt tttcataaaa
    26221 acctccaaaa ttattatata taaataaatc ctctgtttaa ttaatacctt ttaattaatt
    26281 atcattccct agattctatt ttttaacctc tatatactta ttatataatt tatcattatt
    26341 ttacatttta cgacatcaaa aactcaaata aaggagaata aaaactacat taagactcac
    26401 atccataaaa ttataatatt tattttgtgc aatctatgta agctttatcc tcctccctga
    26461 ctattcaatg ctaagctttt atataatact taaaaataat tattctttga ttgtaactga
    26521 atcttctcca tcaatttcta ataaactgac agatataatt tcatgtctag aagtaggtac
    26581 attttttcct acataatctg ctcttatagg caactctcta tgccctctgt ccactagcac
    26641 tgctaattgt attgatttag gtcttcctat atctataata gcatctagtg aagctctcac
    26701 agttcttcca gtgtataaaa catcatcaac taaaactact gtcttatcat ttacattaaa
    26761 atctaaataa gttcctttaa ctacaggttc aacatgaatt ttttccaaat catctctata
    26821 caaagttata tcaatatctc ctgtatctac ttttgttcct tctatttgtt ctattttctt
    26881 agaaattcta tttgcaattg gcacacctct agtctttatt ccaactaaaa ctagattttc
    26941 tacaccttta tttctttcaa ttatttcatg acttattcta gtaattgctc ttgctattgc
    27001 cttttcatcc attaattgag ctttttctac catatcataa ttattgtcaa agatataata
    27061 tatctatttg acaaatctac tcctttcttt taatttttta taaatttatt tttatttaaa
    27121 atttcaattt aaacaacaaa aaaacttctc atcacaagac aagaagctct tatataaaaa
    27181 atatacagtg taatttagca attgtcttac gatatctctg tatcgtttaa agataatttt
    27241 ttaatctatc aactcaaatt atatatttat atttcaaatt tttcaagctt ttttaaacaa
    27301 aatactttaa tataagatat tttatttaaa tttcactaaa tttatttact tatataaaaa
    27361 caaaaaatga tttataagta ttatacaaat ggttatttta tctttttaat aacttcctta
    27421 aaatactcag gtaattctga attaaattcg atatattcct tagtagtagg atgtataaat
    27481 cccaacttct tagcgtgcaa agtttgtcct tttaatttaa atttagtttc ttttggacca
    27541 tatacataat cacctaaaag tgggtgattt atagacaaag catgaactct tatttgatga
    27601 gttctaccag tttcaagcct agctctcata tgtgtaaact tatcaaatct ttctacaact
    27661 tcaaagtgag tgattgcatt ttttccatct tttactacag ccatttttaa tctatcctta
    27721 ggatttctcc ctataggttt atcaacagtt attttatctt ctttaaccac accatagcat
    27781 ataaattcat actccctagt tatagtatgt tcctttaact gttctgctag aaaattatgt
    27841 gcataattgt tcttagctat cataagaaga ccagaagtat ctttgtctat tctatgaact
    27901 ataccaggtc taataactcc atttattgat gacaacttat ctttacaatg atataaaatc
    27961 ccatttacta acgtattttc atagtttcca ggagcaggat ggacaaccat atcctgaggt
    28021 ttatttatta ttaagacatc atcatcttca tatacaatat ctattggaat atcttgaggt
    28081 aaaacttcta atactttagg ttctggtatc tctataacaa tattatcttc ctctttaacc
    28141 agatatctag ctttttctac tttattatta acctttactt ttccatcttt tataattttt
    28201 tgtatataac ttcttgacat atcacctaat tgttctgcta gataaatatc aagtctaact
    28261 tcttcttcct cttcaagtac taaaaactct tttacttcat ccattatatc acctactttt
    28321 actttcaaaa aataaaacat atatacataa aaacacagtt cctacaacta caaatacatc
    28381 agctacattg aatacatatt cccatataac tctaaagtcg aagtaatcta ccacaaaacc
    28441 taatcgtact ctatcaacta gatttcccaa tgcaccagat ataattaata taattcccaa
    28501 ccttccaaat atatgtactt tccttgtatt aagatagtat aatccaaata ccgttgcaag
    28561 taatgcaaca attataaata tccattgatt attttgtaat aatccaaatg ctgcacctct
    28621 attttcgaca taagttaaat gaaatacatt atttattatt ggtattgttg atacatccac
    28681 caaattattc aatacccata ttttagacag ttggtctaaa cctatgagta gaattattat
    28741 taatatatat agcaatgatt tttcccccta taaattattt aaaaaccaat tttatttgaa
    28801 gcacactatt attattatac aaaaaaaatg ctctaaagag caactttatt aaaattgtat
    28861 tttcttaata aagctagaac aaaatttaaa atagtactac tttttttata ttgtagattt
    28921 ctacatattt aaaatcatat cattatgtat aaaaaattta aaaataccat actaatcaat
    28981 attttttgtg tattttatag attaaagatt aatgatgtct gtaatttaaa cttacaatca
    29041 ccactaatct tcaaacaaat atttttactt ttgcacttgc ttatttttat ctaaatgttg
    29101 tataagttca gatactgtta cgaatttata tcctctctct tttaatttag gaattactac
    29161 ttctaaagct tgtatagttt gtgatttatc atttctttta gtgttataat catgtaaaag
    29221 tattatatta ccattttgga cctttgtaag gatagtattt ataattgcat ctactccagg
    29281 gttagaccaa tctctagggt ctaagtttga ccaaagaatt atattcattc ctttagaaac
    29341 tataatatca cagacacttt tactcatggc tctatatgga ggtctaaata tctttggttc
    29401 tactcctatc acacttttta taatattttg cgtatctgtt atttcttttt caacactact
    29461 ataactattt tttgcaacat ttatatgtgt aaatgtatga ttccctattt catgcccctc
    29521 atcatattgt ctttttaata attctttgtt atattctact ttttctccaa ctacaaaaaa
    29581 agttgctttt acatcatttt tctttaatat atcaagtact tgtggtgtaa aatcctcatc
    29641 tggaccatca tcaaaagtca atgctaaaat tttttcatcc tcatttcctt tttttattat
    29701 tacatcttca taatcgtctt ttatattgtc atttaaacta tatgcttctt ttgaactatc
    29761 ttgattatgt gtattatgat tatatgtata tacacctact atagataata aacatataca
    29821 tataccacat attattttct tcatgtcatt acctcttttc taattcattc tagcaatata
    29881 ttttataatg tcagtttttt aatctctcaa tattccattt ttatttaaat cagttaaatt
    29941 tgttaggtct tctgaataaa agttagaatc ttctacatca gggttttgca ttgcatcacc
    30001 taataaatta ttttccttct ttgcacaatc attacataaa cttgtatctg gcaatatatc
    30061 caatctttct aaatctattt gattatgaca taaatcacaa atcccatatg ttccattctc
    30121 tattttagat aatgctaagt ctatttgata caatcttccc tcttcatgat ttattagact
    30181 gttttgcata ttttgcatat ataaatctgt tcccatgtct cctatatgat tatcataact
    30241 agataattct cctgatgaat acttttcact tgtatgttta gttgtatctc caaataaagt
    30301 attatctttc atatcctcta ctaaattagt taaattttct ctttctttca ataatttatc
    30361 tttatatttt ttagtatcca tttttaacac ctctaatttt aatatttaca tcataaaaat
    30421 agtatgtgga aaagtaaatt aaacatacaa taaaaataag atttgattcg aaaaatggaa
    30481 tgtctcaaaa tgaaattttt agttcattta accctctttt ttatatgaaa tcaaatatat
    30541 ttttatcctt tcagcaataa aaaagagact tatctctatt ttgagatagt ctcttctttg
    30601 aacataattt aaatacaatt ttttaatttt tatagttatt attttactaa cttgccaatt
    30661 tatgattatt ttgttcttta atatgttttg cttttttaaa gaataaaaga ccaagaatta
    30721 ttgctacaat aacacctatt ccattagata tattaactgg tagtctaaat ccttcttttg
    30781 cttgcattat ataactaaat gttactacag tcataaaaag tgctggtaat gtagttatat
    30841 aatggttttt atttgctttg actaaatatg cagaaccagt ccacaacatt atcattgcaa
    30901 gtgtttgatt tgcccaagag aaatatctcc aaattatatt aaaatctata aatgtaagag
    30961 caacaccaac tgcgaataat ggtaaagcta ttaaaaatct atttttgact gcatcttgat
    31021 tataattcat tgcatctgct attgtcagcc tagcacttct aaatgctgta tctccagaag
    31081 ttataggaca tgccacaact ccaagtatag ctaaagctcc tccaataggc cccattaatc
    31141 caacagatac tgtatttact actgttgctg ctccaccatc attaaatatc acattaagtt
    31201 gaggtatgcc atggaaatat gacatggctg ctgctgccca aactaaagct attatacctt
    31261 ctgcaaccat tgacccataa aatactggtc ttgcctcact ctctttctca acacatctcg
    31321 ccataagtgg tgattgagtt gcatgaaaac ctgatattgc tccacatgct attgttataa
    31381 ataagtatgg gaataaaggt gttccatttg gattcatatt ttgtaaattt atatttggta
    31441 tgttataccc ctttattatt aatcctccag ctacacctac tgccataatt aataatgctg
    31501 ctccaaataa aggatatatt ttaccaatca atttatctat tggtaaaaca gtagccataa
    31561 tataataaag tattatcact ccaacccata tttgtgcgtt tacacctgtc aatgtcttta
    31621 ataatcctgc tggacctgtt acaaatacaa ctccaaccaa tactaaaaga ataacactaa
    31681 atattctcat tgctattttt gcaccatttc ctagataaag gcctaccaac tctgatgcag
    31741 atgtaccttt gtttttcatt gatagatatc ctgaagcaaa atcgtgtact ccaccagcaa
    31801 agattgttcc aaacacaatc cataaaaatg ctgatggtcc aaataatgct ccttgtatag
    31861 ctccaaatat cggacctaac cctgctatat ttagaaactg aattaaaaag attctcttcc
    31921 atttcattgg cacataatct actccatccc tacaagctat agctggagtt tgatttttgt
    31981 cattggttcc aaaaaccttt tctacaaaag taccatagac aaaataacct actataagta
    32041 ctactattga acctaaaaag cttaccataa attcatcccc ttagttttta tataattgct
    32101 ttataaattt ttatgagttt aagaaaacta tttccagttc aaatagtaat acttttttat
    32161 gctaatataa atattaatta cattaagtgc atatttaagt acatgaaatg actttatata
    32221 tgcattaaca gcctaaattc ttttactttg cttctactta cagttacttc ataatcacta
    32281 ttttttaatt ttaatatgta tgtattatta aaccatggta taatttcttt tactttggtt
    32341 aagtttacga tataagacct atgtgttcta aaaaatgttt tatcatttat aagattttcg
    32401 acttcttata tgccttcttt taatataaac ttttctttct cagtatatat aaatgtctgc
    32461 ctttcattag cttcacagta atatatatca tcaatatcta ttacaactaa tttatcacct
    32521 ttccaaaggc taattttatg tgttatttct tctatctcct gatttactgc ttccttctta
    32581 tatttgtata aattactatt tacattaaat agttcaatat cactcatctc acttttttct
    32641 aatttattca gcatagaaat aattctctct tcagaatatg gtttcaatat ataatcaaat
    32701 acatccaaag aaaaagcatc tactgcataa ctttcatatg ctgttataaa aacaatttta
    32761 ggtcttgatt taaactgatt taatgttttt gcaagtagca ttccatcaag atgaggtata
    32821 tttatatcta aaaaaattac atctatttta ttttcctgaa taaagtctaa cacctctata
    32881 ccattggtaa attcacttac tacctcgatt ccacttttat tttcaataaa atatctcaat
    32941 tcctttcttg ctggaaattc atcttccact attatagctc tcatacttct actcctttac
    33001 ataaaatact atcaaagtcc cattatctat tcttcttata ttaagccctc ttccatacat
    33061 cagtttaagc cttaaatgta cattataaag cccaatctta ttttctggca tattatcttg
    33121 atatacatta tttataattt cctcacttat acctatacca ttatcctcta ttgatattct
    33181 cacagtattt tctaatgaat acggtaactt ttttatggat attttcacta caccagctct
    33241 accactttct aaaataccat gtattattgc attttccact aatggttgta taatcaaact
    33301 tggaatcttt atatttacat cttctatatc ataagataca gttagtaatt ctccaaacct
    33361 agctttttct atctctacaa aagatttaac ttgttcaatc tctttattta tatcaattaa
    33421 gttatcacta tattcaagat tatatcttag ataagttgat aaatttatta ttaactctct
    33481 agccttatct ggactaaatc ttataaatga agctattgtg tttagggaat taaacaaaaa
    33541 atgtggatta atttgtcttt gaagtgcttt tatttctgct ttatttctcg cttctatatc
    33601 ttttttatct ttctcaatcc cctctactat agatataaca aatcctattc caatctgccc
    33661 aactattaaa ggtaaatata ttccaccgat tatttgaatt gctaaagaat gtggatatga
    33721 tattaagtat ataagtaata tagtaaaact ttcagaaatc atgcctacca atattccata
    33781 cattactcta tgttgttttg gtatcctctt atatagaaat cctgataata cacctgctag
    33841 tatacttgat aaaagacatg gaacagatgt tatcccccca atatccataa aatatctatg
    33901 aatccctgaa aaaactcctg ctgtaatacc taccatcgga ccaaataaaa tgccacctga
    33961 tactatagat attattctag tgtttactat tgaccccata taatttatac cactataagt
    34021 tccaaatatg gctaaaaaag taaaaactaa tgctatacag accaagtcat taaaactata
    34081 ttcttccttt tgaaatatct gcttaaatat ttttaacttt gttattagaa gaaacaatac
    34141 tacaataagg cttgtctttt ctattaatgc gattaaaatt gatgttttca taatccccct
    34201 ttaaaaaata aatttttaca cactctaaat ttattatggt tgttataaat tacatatttg
    34261 aagtaatcct atcacaaaac tttccacatt taatctttta attaaataag aaatagttgt
    34321 acttctatta acaactaata ctagctagca taagcttgta ataacttgta gttattatta
    34381 actttacaat tctagtattt aattttatac tttagaaatc tcttttctta gaaataatac
    34441 tttcgaatat catataatac aatattatgt agattcttac tcatacaaca tatttcttta
    34501 aaaattttat actattcttt gttcaaatat ctcatttgat ttaattgtgt taaacacaca
    34561 ttatcatctc tctgttatat atttattata tagccgtata tcgataaagt aaataaatcc
    34621 catatttaaa ataatatgtt tgacaataaa ttattataat gtatatttac cataataatt
    34681 tgtcaacctt gaaagttact tctataatta ttgttaaata attcttctaa aaaaaatacc
    34741 tata
//
LOCUS       DAEHWO010000037        34463 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEHWO010000037 DAEHWO010000000
VERSION     DAEHWO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.037"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(70..1671)
                     /locus_tag="KNP54_002151"
     CDS             complement(70..1671)
                     /locus_tag="KNP54_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBF0893049.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCYGKIITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(1782..2459)
                     /locus_tag="KNP54_002152"
     CDS             complement(1782..2459)
                     /locus_tag="KNP54_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893050.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2472..3167)
                     /locus_tag="KNP54_002153"
     CDS             complement(2472..3167)
                     /locus_tag="KNP54_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBF0893051.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3219..4418)
                     /locus_tag="KNP54_002154"
     CDS             complement(3219..4418)
                     /locus_tag="KNP54_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBF0893052.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4679..6724)
                     /locus_tag="KNP54_002155"
     CDS             complement(4679..6724)
                     /locus_tag="KNP54_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893053.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7135..7944)
                     /locus_tag="KNP54_002156"
     CDS             complement(7135..7944)
                     /locus_tag="KNP54_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0893054.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8028..8561)
                     /locus_tag="KNP54_002157"
     CDS             complement(8028..8561)
                     /locus_tag="KNP54_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBF0893055.1"
                     /translation="MSGAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8711..10060)
                     /locus_tag="KNP54_002158"
     CDS             complement(8711..10060)
                     /locus_tag="KNP54_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBF0893056.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSITSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(10072..11454)
                     /locus_tag="KNP54_002159"
     CDS             complement(10072..11454)
                     /locus_tag="KNP54_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBF0893057.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIESGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            11698..12912
                     /locus_tag="KNP54_002160"
     CDS             11698..12912
                     /locus_tag="KNP54_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBF0893058.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            13089..15002
                     /locus_tag="KNP54_002161"
     CDS             13089..15002
                     /locus_tag="KNP54_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893059.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            15273..16247
                     /locus_tag="KNP54_002162"
     CDS             15273..16247
                     /locus_tag="KNP54_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBF0893060.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            16268..16543
                     /locus_tag="KNP54_002163"
     CDS             16268..16543
                     /locus_tag="KNP54_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBF0893061.1"
                     /translation="MNAIIHANEKDNLVTCVRPLIKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            16556..17719
                     /locus_tag="KNP54_002164"
     CDS             16556..17719
                     /locus_tag="KNP54_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBF0893062.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VNYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            18056..20335
                     /locus_tag="KNP54_002165"
     CDS             18056..20335
                     /locus_tag="KNP54_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0893063.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(20430..21770)
                     /locus_tag="KNP54_002166"
     CDS             complement(20430..21770)
                     /locus_tag="KNP54_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0893064.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(21782..22564)
                     /locus_tag="KNP54_002167"
     CDS             complement(21782..22564)
                     /locus_tag="KNP54_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893065.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(22579..23601)
                     /locus_tag="KNP54_002168"
     CDS             complement(22579..23601)
                     /locus_tag="KNP54_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBF0893066.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(23607..24620)
                     /locus_tag="KNP54_002169"
     CDS             complement(23607..24620)
                     /locus_tag="KNP54_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBF0893067.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(24748..25686)
                     /locus_tag="KNP54_002170"
     CDS             complement(24748..25686)
                     /locus_tag="KNP54_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0893068.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLAKPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            25956..26420
                     /locus_tag="KNP54_002171"
     CDS             25956..26420
                     /locus_tag="KNP54_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893069.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(26532..26849)
                     /locus_tag="KNP54_002172"
     CDS             complement(26532..26849)
                     /locus_tag="KNP54_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBF0893070.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(26862..27593)
                     /gene="chbG"
                     /locus_tag="KNP54_002173"
     CDS             complement(26862..27593)
                     /gene="chbG"
                     /locus_tag="KNP54_002173"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBF0893071.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLLSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(27619..28929)
                     /locus_tag="KNP54_002174"
     CDS             complement(27619..28929)
                     /locus_tag="KNP54_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBF0893072.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(29026..30339)
                     /locus_tag="KNP54_002175"
     CDS             complement(29026..30339)
                     /locus_tag="KNP54_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0893073.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(30361..30672)
                     /locus_tag="KNP54_002176"
     CDS             complement(30361..30672)
                     /locus_tag="KNP54_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0893074.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(30872..31576)
                     /locus_tag="KNP54_002177"
     CDS             complement(30872..31576)
                     /locus_tag="KNP54_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0893075.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDVRVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(31667..33028)
                     /locus_tag="KNP54_002178"
     CDS             complement(31667..33028)
                     /locus_tag="KNP54_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0893076.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            33527..>34463
                     /locus_tag="KNP54_002179"
     CDS             33527..>34463
                     /locus_tag="KNP54_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0893077.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYII"
BASE COUNT        11870 a         5831 c         4206 g        12556 t
ORIGIN      
        1 aaatctcaaa cttcgtcttt acttacttag atatttattt actttctaaa tcctattatt
       61 tttaaaacct tatcttttta atacttcacc acatttattc tcagtaatct ctccattttc
      121 tagcgcaatt tttccattta caattacata ttcaacacca ttggctagta attgtggctt
      181 tgaaaaatca atatcttctg acctaggata actatagtta tccatgtcaa taactgctat
      241 atcagctatc aacccttctt taagaatacc tctatttttt attttaaatt gcctagctgg
      301 taatgaagta actcttctta caatctcttc caatctaaca ccagactttc tgtacatatt
      361 gaagaaaatt ggaaaagctc ctcttctttg tagttcaaac catgacatat ccccacccac
      421 actaaacaaa caatctgaac caaccataac aaatggatta tcaattattt tatcatcatg
      481 tagtttatct gggaaatcag ctctatacat tcctcctaaa caaaagataa gttcttcgtc
      541 tccatctaaa agtaaatcga gtaataactt gtcctcatct attccttttt gtgtagctat
      601 ttcacgtatt gatttctttt ccatattaat atctttagtg tttagaagta ttatactccc
      661 cctatctcca agtataaatg cttcttttaa tataagtgtt cttccctctt catttctaag
      721 agcatccatt accccatcta tacctaattc aaatagacta gatgatattg ccataataaa
      781 ttgaattact ctttttttct tcatacaatg cccagaactt cttggtactg tgtcaaccat
      841 tatttcaaca ccattatacc tagcctttaa tatctcatca aatgcttcta tttcaactgg
      901 acttaagtga gatacttgaa ccctagcacc acttttctgc ccaacctcta tggcttcttt
      961 tactgcatta tatcttccta tgtaatctct aatatgagat gtatatatac catcatgctc
     1021 tttaatctgc cttgcaatat caacaagttc atcaatatca gcatacttac ttggtatata
     1081 tgccaatcca gtagatattc caaaagcacc acttttcatt ccatcattta ttatatctgt
     1141 aatttcattt ttttcctttt ctgtaggagg tctatcctta gaacctccca taacactcca
     1201 tcttatagtc ccatgcccca acaagaatcc catattgaca gaaataccac ttttagatat
     1261 aaggtcacaa tattctgtaa aattattcca acatttattt ttatctataa gatacttttt
     1321 ttcttcttca agtaatagac catttttata catatattca tatacatttt cagaagaata
     1381 tggtgttata gaatgtccac aattaccatt tatagttgtt gtaactcctt gttttagaaa
     1441 cttttcaaat ttaccatcta gtattgctac tatttcttca tgaacatgag ggtcaataaa
     1501 tccaggtgtt ataatttttc cataacaatc aatctcttta tttgtattgc tatttatctt
     1561 agaatctatt tttgctatta agttgtcttt aattgctata tctccataaa aaccaggatt
     1621 acctgtacca tctattataa atccattttt taagattaaa tcatatatca aaatattccc
     1681 tccttaaaaa ccaattttta aataatctta atgtaatttt tatatttgaa aatcaaatta
     1741 ttaaatttca tatttgaaaa ttcactatta tttcattgta attagtcact aagcttatct
     1801 ttatacatag ctcttgcaat taatatagta ccaaatacac atataagaac tactagagac
     1861 tgtggtatta taccttgctt tgataatata atagtcaata cagatattac aattgctact
     1921 agacctaatt ttttatcttg taaaaatact tgtccaaaaa ctgacccaaa tagagctggt
     1981 aaaattaagt ttaatttttc tactacttca gctggaattt tagatagtac gcttcctcct
     2041 aaaattaccc ctatagttag tatacttata ttcactaaaa tagatacagc tattcctatt
     2101 gtagatatta tcgagccttc ttctgtacct gattcaactt ctgctgcctt ttgagctgct
     2161 attgaacatg gtagcctcat attagatata ttaccagaaa gaaaactcat ataagttcct
     2221 gggataccta agattggtga ataagaaact ggttctatta tgtaatttgg agcactcata
     2281 ctgacaattg ccattgtact tgctaataat gctgatattg gaggcataat accaaatcca
     2341 aagctcaaaa ttattccagg aactaatgct gctataatac ccaaagatag tgttagtctt
     2401 ccatacctta tcataaaagg taaatattct tcattgtata tagattttac tttactcata
     2461 aaactccccc cttatattac tgaagctatt atcattccgc taaacattga tattgtaagc
     2521 ccccactctc ttaaccattt tatatttttc ttcttttcaa gcatacacaa tattaccatt
     2581 atagccattc cacttataca tgcaattgtt ccattatcaa aacgcaacac cctatcagca
     2641 tttagatatg caaatgaacc caacattgct cctagagata ttattggtat aaatgatttc
     2701 ttgccactag atataacatt ggttatctta tctagtttat gtccaaatag taatgtgaat
     2761 attatccatc ctaaagaacc taatatcata gtccaaactg catttgtaaa tgcaagtttt
     2821 gtcatttcag gagaacctaa agttatacct aatgcatctg ttccaaatcc ggctgacatt
     2881 gattcaaaaa ttacagaacc tataaatgat aatctcatcc atgctatagg cccacccata
     2941 gttactataa gcgataccat tccagcaaat atagtcattg aaggcccaat agctgaaata
     3001 gcactactct taacagctga ctttatttgt ttatctgtta ttcccattgt tttaccaact
     3061 ttgcaagatt ttatagcaaa tataagggat tgtaccacta ctattgatac tgctactgta
     3121 ctcgctatcc acaaaagtgg atgattagct aattttaaat aatccattta taaaacctcc
     3181 ctataaatcc tcaaatttta ttaatatttc taatatatct atttccaaac ctgttttagt
     3241 actctaagta tatttccacc tagtaccttc tctatttcct catcactata tccatgcttt
     3301 actaaatatc taacaatgtt ttttgaagtt tctgttgggt tctcaagacc ttttacatat
     3361 tctactttgg gatgttcttt tgttcctgtt atttttttta tatcaaattt agcagctagt
     3421 actgagtgta attttacatg gtcgccatat actgtatctg gtccaaaagc tacatggtct
     3481 attcctacta aatttttaat atactcaaaa tgttccataa atgactctat tgaatgttct
     3541 ttattcttct ctgttattgt agtatgaggt gctgcttcta cacctataac ccctcctttt
     3601 ttagcacatg ctattaatac ttcatctgga gttagtctct ttgtgttcca taaacttctt
     3661 gccccaacat ggcttaatat tattgggtcc ttgctatatt ctattacatc aagtgtagtt
     3721 tgaactccaa cgtgagagca atctattgcc attccaattt tattcattct ttcaacagct
     3781 ttttttccga aatttgtaag acctccatct ttctcttctt ttagtcctga acctaatgca
     3841 ttggattcgc tgtatgttat acccattaac cttataccaa atccatacag tatatctatt
     3901 ctatcaagtt cattttctat tggtgctgca ccttctaatg ttggtatcaa tgctacttta
     3961 ccttcacttt tagctctgta tatatcttct actttttcac actttataac aaaatcttga
     4021 tgagctaaat cacatagtct catgcctaaa tctattaata tatcatccca tttccaccct
     4081 gaatttgatg ttatcgtaca tacaccatcc attaaattat caaatatagc atcataatat
     4141 cctcttgata atgcttcata agcacatctt tgtttacctt ccctattata ttcaaatata
     4201 tctctttcta ggtgttctgg aaataatact ggatgttcat gtaatgatat aaatattttt
     4261 tcatccacta tacttttaac cttagcttct tgaatatcat ctaattcaat aaggtattct
     4321 ttaactcttt tatctccttt acacatctca atagatgaaa tatcttttcc tttttctaaa
     4381 taactatagg cttcatatcc tttgtaagct gacttcataa caacatcctc caagttctac
     4441 aattttttat atttttccta tgtagcaatt gatgtgccaa aatataaatt ttaattgtat
     4501 aataaatctt gcaaaaaata aaaacagtag taaggttgat atttactact gttttattaa
     4561 aaataatctt cttagattat ttattcaata tttttgaatt atcttaatct taaagataat
     4621 tttatttatt tctatccatt atagggattt ttttagggtg ttttgccttt ttagtcccct
     4681 atatcactcc cttaattttt acatatgata taaagttctt tccttcatca gttataaaac
     4741 taccttgttt ttttactcca gataaaagta aaccatggct ctttaactta tctattcttt
     4801 ttctaatttg gtctacactt aaaactatat ctttttcttt taaaatctct tgcagtttat
     4861 ttcttcctaa taatatattt ttattattcc aagtttctat actggtcaat atacatatac
     4921 tttcctcaaa gaaattagat tgtttgaaat ctaagataat tgaatcgaaa ttttcattaa
     4981 ctaaagtatt gtttttttca aatctaaatt gttctggcaa atgctcgtaa tctactctat
     5041 cttcctcaac tatagtatca atataataaa ttaaattttt aagctctctt acatttcctg
     5101 gccattcata caatgttaaa gcttgcattg attcctctgt aaaacatttg ttgctattta
     5161 tttcatctaa aaaatactta cttataagag gtatatcttc cttacgttct ctaagtctag
     5221 gtatctctat atgtaataca ttaatcctat aatacaaatc ttctctaaaa gaaccttctt
     5281 taattttttt ctttaaatct ttatttgttg cagctataat tctaacatct attggtataa
     5341 ttttacttcc gcccattctc ataacttctt tttcctgtaa tactcttagc aatctctgct
     5401 gtacatctaa agatatatca cctatctcat ctaaaaaaat tgttcctgta tgtgctcttt
     5461 caaatatacc catttttcca ccttttattg ctcctgtaaa acttccttca tcatagccaa
     5521 aaagttcact ttcaataagt gtatctgaca aagaagatag attaactgca acaaatggct
     5581 tgttttttct tagagattca ttatgtattg cctgggcaaa tatttctttt cctgttccat
     5641 tttctccaag tatcaacaca gaaaagtctg tagttgctat ttttcttgca atattaattt
     5701 tttcttttat tattttactc tcacctacaa cactctcaaa tgtatacttt gatacaaaac
     5761 cttttgactg aagtttattt tgaatcttgt cctcaagcac ttgaattgca cttatatttt
     5821 taatgcttat aatactcttt attcgttcat tattttcata aacatttact ttattaatta
     5881 tcagtttttt gttatttaaa tttactactt catcattaac ttcatcttct tgaaaaaata
     5941 tttttttgac aaccttatca ctaaataagt ccataaagtt attagatata atttcatttt
     6001 ggtctattcc aactagatta gaaaatactt tgttgcaata tataaatttt cctaatttat
     6061 caacagaagc aataccttca tctataatct ccaaaaaact cttcatggtt ttattcatag
     6121 ttgtataata cctatatcca cttactgtat cttcattgta tttttcctta ataatatgta
     6181 gtttatctat agatatattt agttttgtaa agatttctat aactgtattt atatcaatta
     6241 ccttatcacc tatgtcaatt atttgcttta tgttttgtgg tatgctgttt ctgcttcccg
     6301 taataattcc aatctcacat ttagacttat cacaacctgg ataatatggt attagattaa
     6361 tatgaattaa tcctagtttt ctaattatct tggcagtttc atctgctgac tctttataag
     6421 catctataac cataacatca gaatcatttt ctatacttat tatctgattt atattttcaa
     6481 tatttatagt acgatgtact attacaatag gtatattttt atcaatatta ttatgtatat
     6541 attcctttat atcattgtct gaacatacta caagctcata gcttgacagt tcaatattta
     6601 tcctatttac atataccaag ttatctatat tacaaaattc tccaaatata ttttccaatt
     6661 gttttgatat atctatattt attttgtcat cagttgatac aaataaaata ttatgttttt
     6721 tcatagtccc acctcctgtt taacgagtat agaaagtaat aatttggtct attgtagcac
     6781 tttttaaaaa agttttaaat cttaaaaatc aaattttgta ccatttacta ttattttcca
     6841 taataaaata atgtaagcta tcttttttca catataattt aatttctaaa acggttagtt
     6901 tgacattatt ggaatataaa taaaaattta atataaattc gttaatatat taatacattt
     6961 ttaagaatga caaggaataa attataacaa attttaggaa tatataataa tagggtctca
     7021 gaacttagtt acaagttcta aaaccctatt tgtttagtgt aaaaaacatc ataaaattta
     7081 gcttaaatct tttcacataa tattactctt tttctaagtg ataataaaat atatctattc
     7141 ctctaaaaac tgtaaaaatt cctgattaaa tagtttaagc tcatcataga atatagcatg
     7201 accactatac tcaaaagtat ataaaattga atcttctatt ttttcattca taaaaactgc
     7261 aaattcatac ggacatattt catctaattt cccatgaaat ataccagtag gcactcttac
     7321 acattttaaa tcattaaata attcttcatc tcttaaagat acagcagttc caatagtgcc
     7381 aatacctgat gcactaaaac caatatcatt aaaccatctt ctaaagcttt ctggtggatt
     7441 tgatgcaaat actttttcgc caaaatcggt taccatttct ggtctatcag tacatgcttg
     7501 tgctatcaat ttatttacat cttcacgtgt cataccatat ggaaattctg gaggtctttg
     7561 tacaaatgat ggtgcagcag ctgcagctaa taccaatttt gacactccat atccattaaa
     7621 taaactcata tacctaagta cgattgctcc tcccattgaa aaaccaacaa gggtaaagtc
     7681 ttttaatcca atagcatgta ccaccttata aatatcgtct gctaattggc tataagtata
     7741 tcctcctgat gttgcatcag atttaccaaa acctcttaaa tcaattgaaa ctgttctata
     7801 tccgagtttt ggcaatatat ttgtttgata ttcaaatatc ttatgtccta agggccaacc
     7861 atgtataaaa agtacagttt ttttagcact cggattcaaa tcatatactg ctatgtttat
     7921 atcattcaca tatacataat acatatcaac agcaactccc ttcaagaaaa tgtatgatgg
     7981 ttattttata tatatgaata aaatgatgaa taactaaatt ttcaaattta tttacaatac
     8041 ttctctattg ccttttcaaa taaacttaca tgaagttttt catctaggat tattctattt
     8101 aatatagctt ttatataagg gtcttcaata agacttatat ctttataata attattaata
     8161 gccacatgct ccaaatgcaa atctagtttt aatctgttac aaatagaatt tccataacat
     8221 acaaaaccac cattccaata tgcaccacaa gaacttgtag aacctctata tacaggattt
     8281 ccacccaata atcttatagt ctttgctaat atctccatat gtaacatttc tgttatagat
     8341 atatttatcc acatttcact taactctcta tgcgtttcat ctaaatcaaa attatggtat
     8401 agatattgat ttacactcgt aaattcactt gatactccag catagtcatc catcaataat
     8461 tctgcataat acttatttgg acctaaaact tttatctctg gatatggctc atcacttgaa
     8521 tatccatttc gcttgtgcat gtcataatgt gcaccactca taatatctcc tcctttaaat
     8581 ttaatgtatg atattaattg tatgcatcac aactttttca tataacttag ataataaaat
     8641 ctacttaaat aataaaaagc catattaatt aaaattaaca tgacctttta tccacaaaat
     8701 tactttttaa ttattcatct tttccagcta ctgatagctc tttaataaca actgaaggtg
     8761 aacctatact actcattgga aattctaaat cttctcctat agcttcaata tctttcaaca
     8821 ggtcaaaata gtttcctgct actgtaattt gctccactgg aaatactttt tttccttctt
     8881 tgatataaaa gcccttggca gctaaagaaa agtctcctgt tactgaattt gcacctgaat
     8941 gaagtcctgc aaagctagta accatcaatc cttcatctat atcctttata atttcatcta
     9001 aagatttatc tcctttctct atataaaaat tagttggata tatgcttata ggtgatgaat
     9061 atgaagattt tattccattt cctgtagtct ttacacctgc cttattagcc gtttttaagt
     9121 tatgaagtaa agttataagc tttccattta aaacaacttc ttttttaaat gtagctactc
     9181 cttcatcatc aaaaggagta gatgccatac cattttctaa aagtgggtca tcaactattg
     9241 taactatagg agatgctatc atgtctcctt ctctattttt caataaagat aatccttttt
     9301 gagctgaatc tgcattaaat atcccagaaa atgtgctaag caaagatacc atagcttcat
     9361 taagcaatat agttttatat ttacctgatg taatactctt accacctact ttagataaag
     9421 cattatcaac accaagtttt gctatctcac aaggttttat ttcttcaata gaatttgcta
     9481 tattatatcc tattccatca tatttttgtc cattgtcttc tatgatagga actacaaacc
     9541 ctataagcat attagtttta ttgcttaaat taagaccttt agtattagat ataccattac
     9601 ttgatacaga ataagatata gtacatttag ataaatttac caccttatct gaataagctt
     9661 tagtctctct ttccatttct aaagctaaat caatcaactt atctgcctct aaattttcta
     9721 gctctttaga ataagtcttt acatcattat agtgcttatc tccttcatat ataaattgta
     9781 catcttcatt ttcaatagtg tttactccat cttttacatt ttttatcaac atatcaacag
     9841 ctttatcatc taaaatttct gtataagaat aacctatctt tccatttacc ttacctctaa
     9901 aagataaacc aaaagattta tcaagattgt atttctcaac ttctccttca tatatattta
     9961 tacttaaatt ttctcctgta taataatata tttcacactc ttcaaaacct tcacttagag
    10021 cctttttaaa taatatatct ttaaaatttt taagttccac aattatccct cctatcttcc
    10081 acctacagta atttctttta cccttatcat aggttggcct acattagttg gtatacttcc
    10141 tgatgatgag ccacacatcc cctgagcttg ttttacgtta ttcccaacca tatctatatt
    10201 cataagtata tcgctacctt ttccaattaa actagcacct ctaactggct cttgtatttc
    10261 tccatttttt attaagtaac cttctgaaac tgcaaaatta aactctcctg ttacaggatt
    10321 tacagaacca ccacccattt ttttagcata aagtccatct ggtattgact ttataatatc
    10381 ttctggtcta tcttctccag cagcaatata agtgttagtc atccttgaag ttggtgcaaa
    10441 tttgtagttt tgtctacgag aacttcctgt aggattcatt cccattcgtc taccattaag
    10501 tttatctatc atataagact tcaaaattcc actttcaatc agtatattct tttgagttgg
    10561 atttccctca tcatctatat tcatagaacc ccagtagttt ggtattgtac catcatctat
    10621 agctgtaatc tttgtggaag caatctgttg acctaattta tctgcaaata cagagttccc
    10681 ctttgcaact gatgtagctt ccaaagaatg tccacaagct tcatgaaata ttactccacc
    10741 aaatccatta tctattgcta ccatcatatt acctgcagga caatttttag catgcaacat
    10801 agtatgcgct actctagctg attcttttgc ataatattct gggtctattt cttcaaatat
    10861 ttcaaaccct ttacaacctc caggaccttc aaatccagtt tgattttcat tacccttaga
    10921 tgcaattgaa cttatcccta gtctagttct tattcttcta tcctcaacat atataccttc
    10981 agtgtttgca attaatattt tttggtcttt atccaaataa ctgacactta cttgagatat
    11041 atcattacta aattcttttg cactcttata tgcaaccttc ataacactta ctttatcttt
    11101 atttcctatt gaatttggat aaatttttat attatgtatg ttatttattt taatactgtc
    11161 atttaatatt acactttttc catcttccaa tttacctaaa gcaacagcag ctttgtatgc
    11221 tacatccaac agactattta atgaattgtc acttgtataa gcatatatac ttttcaatcc
    11281 tttaaatatt cttattccta taccataatt tcttccacct attgcatttt ctactttatt
    11341 atctattaaa ctaatagaat tatttatagt gtcttcttca aaaatctcag caaaatctcc
    11401 tccagtaatt agacattttt ctaatacctt agaagctata ttttttgaaa gcataaattt
    11461 acctcctact ttaaattttt aattaacttt tattcaatct ttttacttgt taacaaacat
    11521 tatatactat attacttaaa ataaggtaat tatgaatata ttatacatat gttttatact
    11581 aaaatgttat cacattttat ctatacatac ccatataact agataattaa aatgtataat
    11641 attatttgct atagaaaata atacactcat acataataaa ttttaggagt gaagtatatg
    11701 aatcaagaat atgtaaaagg aaatcctatt tttactaata ttaataaagt tccaagacaa
    11761 tttccatacc ttactgatga tattgatact gatgttataa ttgttggtgg tggcgtaact
    11821 ggatgtattt gtgcttacta tctagctaaa aacaatataa agtctgtcat tcttgaaaaa
    11881 ggaaggattg cacatggaag cactagcgtg acaacttctc tattacagta tgaattagat
    11941 gacaatttga tagatttaac agaggttatg actctaaaag atgctctaaa agcatacaac
    12001 ctttgtactt cagcacttga agaattagat acatttatag agctatatgg aaataagtgt
    12061 gattatgcca aaagagatac tctactttat actgccaaca aacttgaagt taaggctatc
    12121 aaagaagaat ataacttaag aaaagaaaat ggatttgatg ttgaatatat tgatgaatcc
    12181 acaaaccctt ttagctttga tttaaaatca ggattgatag caaagaatgg aggacgagaa
    12241 ttagacccat ataaatatag tcaccatttg attgatgtaa gtttaaaaaa tggtcttcaa
    12301 gtatatgaaa atacagaagt aaaaaaagta gatttatcaa atgataaggt tactgctgaa
    12361 gtatcgtatg gatacaaagt tcatggtaaa aaattaattg tagctacagg gtacaataca
    12421 agtttattta caaaaagaaa ttttgcaact aagtcaaata cttttaatat agcaacgaaa
    12481 ccacttaaaa acatagcttc ttggaaaaac aacattttaa ttagagataa ctgtgaccca
    12541 tataattatc taagaactac taaagacaat cgattaatta taggtggtga agatgtaagt
    12601 tttgatgata tagaaaatga aactttagcc aatgaaaagt atgatatttt agaacaaaga
    12661 ttgaaaagta tgtttaagga tataaaagac attgaagttg aatataaata ttgtggttgt
    12721 tttgcttcaa ctttagataa tttaggtttt attggtccag ataataaaaa taacaatcta
    12781 tggtattgct taggttatgg agcaaatggt atactctttg caatattagg aggtataatg
    12841 ttaagtgaat tatatcttgg caaacaaaat aaaaatatga aattatttaa agtagataga
    12901 tttgataaat agatattata tattaaaaga ctgtaaaaag atgaaacttt ataattctaa
    12961 aagttaactt tgatacagtc ttttataatg ttccttttaa aaatacttta tttataatta
    13021 aatataaagt aaaatgttaa aatataacta ataaaattta gtcataagat aatatttaag
    13081 tttatttgat gaaatatgga ggaattatta tgaaggaaat actcgttatt gctcccacta
    13141 aaggaaccta tgaaaaatca attcacatag ttaaaaaaaa caaatataca aatattgatg
    13201 ttgtatttgg caatctaaaa gaaggtatac ctcttgctga aaaaagtatt aatcatggta
    13261 ctagaattat cataagccga ggtggaactt acaatatgtt aaaagctact tacaatatac
    13321 ctatagttga aattaaagta gatgcttatg atattataaa aagctacaag gaggtaaaaa
    13381 attccaacga accatttgga ataattggat ttaataatgt catctacggt ttcgatatta
    13441 tagaagaaat attgaataag aaaataacta tgattgaaat tgaaaaagaa gaagaaattt
    13501 atgatgctat agaaaagtac agaaagaaag gtataaacac atatatagga gataccactg
    13561 ttgcacatat tgttaagaga cttaattgta agggaatatt aatcgaatct agagaagaaa
    13621 acatacttag agccattcaa caagcagaac aaatactcga agcaaccaag gatgaacaaa
    13681 aaagaagatt acagatagaa gctatgacag attttgtaca tgatggaata ataacagttg
    13741 ataaaaattt taaaataaca ttatttaata agagtgctga aaaaatattt ggtataaaaa
    13801 aagaaaatgc actttatcat aatgttgtag atgttatccc aaacacagtt cttccacaag
    13861 tagttgagac tatggaacct caaattggtg aaatacaaaa tatagggagt acaaaaatta
    13921 ttacaaatag agttccaata attgttgatg gtcagattca aggggctgtt tcaacatttc
    13981 aagatagcaa ggagataagt tcttttgaac atacaataag aaggagctta ttaagcaaag
    14041 gtctatctgc taaatacact tttgatgata taattcatgc tagtgaaaag acaaaagatt
    14101 gtatagaact tgcaaaaaaa tatgcttgtt atgatactcc tatgattatt actggagaat
    14161 ctggagttgg taaagaacta ttttgtcaaa gtatacataa ctatagtaag cgtaaaaatg
    14221 caccttttgt tgctgtaaat tgtgctgcca tacctccatc tctaatagag agtgagtttt
    14281 ttggttatga ggaaggttca tttacaggtg ctagaaaaaa aggtaaagca ggtgtattcg
    14341 aactagcaca tgaaggcaca atcttcctag atgaaataag tgaaatccct cttgaacttc
    14401 aaggtcgatt attgagggta ttgcaggaaa aacaagttat gagaattggt ggtgataaag
    14461 ttattcctat agatgtaaaa attatctgtg cttcaaataa agacttaaaa aatatgatgc
    14521 gcaatggttt atttagacaa gacctttatt ttagaataaa tatactaaca ttatatcttc
    14581 cttcattaaa agaaagaaaa gaagatatta taaaattatc agaatttttt atacataaat
    14641 attcaagcaa atacaataaa acgcctttaa ttatcactcc aaatattaaa aaggcacttc
    14701 ttgaacgaga atatgaaggt aatataaggg aattggaagg tatgatggaa agggctgtta
    14761 ttgtggaatc atttgactcg attttattag aaaagcttag caatgaatat acaaataata
    14821 tagttgataa agataatagt gattttgaat gcagtaattt agatttaaaa actttagaaa
    14881 aaaaatatat ctataaaatt tataacgaaa ataatagaaa tactacaaaa acctgtgaaa
    14941 ttctaaagat aactcgctcc actctatggc gtaagttaaa agaaatagaa gatgatgttt
    15001 aaaaataata catatctata tatatcaaaa cgttttatgt ttaattttaa tacataagac
    15061 gtttatttgt tttcaataaa aaatacaatt atatgctaaa aagaatcttt gtaagtgaaa
    15121 ttctcgtcaa tcatactttt aattataagt aatctacagc atttcaatcg attattaaaa
    15181 ataatcatga taactaaaga tacaaactct atatattggc atagtaattg cttttataat
    15241 acctatataa aaatgaaagg gagtgatact agatgcacat cttaaaatca gtgaaaaaga
    15301 taccaggagg acttatggtc tgtcccttgt tattgggagc actatttaat acagtatgtc
    15361 cacaagctct tgaaattgga ggattcacaa catccttatt taaaactggt gcaatgagta
    15421 tacttgctct attttgtcta tgcaatggag ctcaaatcaa tatcagacaa gctggtaaac
    15481 cattgactaa aggtatagta cttacagcaa caaaatttat aattggtgca gtattaggta
    15541 ttattgttag taaatttatt ggacctaaag gtataattgg tattacacct cttgccatag
    15601 ttgctaccat gactaattca aatggaggtc tatttgctgc tcttgcaggt gaatatggag
    15661 actccacaga tgttggagca atatctatct tatctctaaa tgatggtcct ttttttacaa
    15721 tgcttgcttt tggagtaact ggacttgcaa atgtacctat agtagcacta tttgcagcac
    15781 ttataccaat actacttgga tttatacttg gtaaccttga tgaagatata cgagaatttc
    15841 ttgcacctgg tacaacatta ttaattcctt tcttcgcttt tcctttagga gcagcattaa
    15901 actttaatca aattataact gctggactac ctggagttgt acttggttta ggagttacta
    15961 taataacagg tatgggtggg tactttgtaa tgaaacttat acgtgcagaa catccagcag
    16021 taggtgcagc tacaggtaca acagccggaa atgcagctgg tactcctgaa gctttagcag
    16081 ctatagaccc tactctagct acaatagcag ctgtttcaac agtacaagtt gctgctgcta
    16141 ttattgttac agcaatatgt tgtccaatgt tagtttccta tctagataaa agagaaaaaa
    16201 agaaaaaatc tatttttaaa acaaataaaa atattgaagt aaattaatac ttaaggaggt
    16261 aaaattaatg aatgcaatta ttcatgcaaa tgaaaaagat aatctagtta catgtgtcag
    16321 acctttaatt aaaggtgaaa aagtttcaat tgatggaaag tcttacatag taaatgataa
    16381 tatacctgtc tttcataaga tggctacaga agatgtaaaa aaaggtgatg ttgtatacaa
    16441 atacggtgaa attataggaa ttgcaacagt tgacataaaa actggtgact atgttcatgt
    16501 acataacatt gaaagtacac gtggtcgtgg agataaaaaa taggaggaag ttaaaatgaa
    16561 attaatgggt tatttaagag aaaatggtca gtttggtatt cgtaatcatg ttttaattat
    16621 tccaacatct gtatgttcaa gtgagacagc tacaagaata gcatcacttg tgcctggagc
    16681 aatagcaatc cctcatcaac atggatgttg tcaaattggt tctgatatag agcttacagc
    16741 aaagacatta ataggatttg gaaaaaatcc taatgttgcc gcagttttag tagttggtct
    16801 tggatgtgat ggtattcaag caaaagaatt agcatctgaa atagctacaa caggaaaaaa
    16861 ggtaaattac gttgttatac aagaatgtgg tggaacatta aaaacagttt ctaagggagc
    16921 tgaaatagta agtaaaatgg ctcgtgaagt atcaaaagaa gtaagagttg aatttggtat
    16981 gagtgaaatt acattagcac ttgaatgtgg tggttctgac ccaacaagtg gaatagcttc
    17041 aaacccttca ataggcgttg catcaaacct tcttgtagat gaaggtggaa gtagcatact
    17101 aagtgaaact acagaagtaa ttggtgcaga acatttgttg gctacccgtt ttgaagatga
    17161 agaaatgaaa gataagtttc ttaaatttgt aagtgatgta gaaaaaagag caattgctat
    17221 gggagaagat ttacgtagtg gtcaacctac tccaggcaat aaagctggtg gactttcaac
    17281 aattgaagaa aagtcacttg ggtgtatgta taaggcaggc aataagccat tcaaaggtgc
    17341 tcttgaatat gctgatattg tacctcctga taaaaaagga ttatatttta tggatactcc
    17401 aggtcaagat atagattcta tcactggtat ggtagcaggt ggtgcacaaa ttgtaatctt
    17461 ttcaactggt agaggtactc caacaggaag ccctatttca ccagttatta aaatcactgg
    17521 gaatagtgat acatacaaca aaatgccaga caatatcgat ataaatgcag gtagaattat
    17581 aacagatggt gctaaaatag cagatatagg tcaagaaata tttaatgaaa taatagaagt
    17641 ctgtaatggt aaacatacca aagctgaaag tcttggtcat agagaatttg gcatttacag
    17701 aatttcatct acattttaga ttgtaacaaa atatctttta taaatataat acttatgtag
    17761 atacataagc taaaagttct ttctaatact ataaaaattt tctatactga aaaggaactg
    17821 tatcaaaatt attttgaaaa cagttccttt tttaacctct tttactcaaa atattataaa
    17881 ataagattta aacaataaac gtatcttgat taatctctaa gaagacataa ataaagctaa
    17941 atgtaaagtg ggataaataa aatttaatat ctttgtatga aaagatattt ggtataatat
    18001 gtctgagaga attcttattt gtaaacaaat aaaggatgga ggatgaaaca aaagaatgaa
    18061 ctttgaaaac acaaaaaata aaaaaataat agctacttta ctattgacac tccttttaat
    18121 cgtgtcatta acatgtgtca cttttattat gaatctaaat aaagtaacac ataatgaaac
    18181 agaacgatat cttgtagaag tttcacaaag tatttccact acaattaatg tgaaatgtaa
    18241 aagtatattt aggacactat attctatggg agatacttat tttgagatta atgatagtga
    18301 aaaagaagtc aatagatact tatcaaaaaa attaaaatta tttgaatttg attggttagg
    18361 tattatagat tctaatggaa attttgtaag tgcccttaaa gatacaggta atgttaaagg
    18421 acaagacttt tatagaaaag cccttcaagg caaagaaaca attactcctg ttaaatcaca
    18481 atctggtaca tatggaattt tatattctgt accactatac aatggtgata aaattgttgg
    18541 agctgttgct gcttggaata ctattgatac tatgagaaat ttattaagtg tagaaagctt
    18601 tcatggtgaa ggattttccc aaattatcga ccaagatgga aattttattg taagttcagc
    18661 aaacaaaaat gctccaaaaa atgtggtaaa tttttttgac atgattaaac accaaggaaa
    18721 acaggttgat aaaaataaac ttgaagaaat gaaaataaac ttaaaaaaga acaaaactgg
    18781 ttctatgtat tatacattaa atgatggtat ttctaaggca atgcattatc ttccattaca
    18841 agaagaaaac ttatacctcc tttcaattgt tccaacaaaa acagcaagtg cacagtttga
    18901 tttacttcta aaaaaagcaa tcttcatcaa tattttaatt gttatactat ttttattgct
    18961 tattatattg attatgttta taaatcaaaa gaacagggca caacttataa aaatcgccta
    19021 tgtagactct gtaactaaag gttacagtaa agcacgtttt gatattgaag ctaaaaaaat
    19081 tatacagtca tcttcatcag aaagctattc attggtatct ataaatattc agaaattcaa
    19141 acttattaat gattcttttg gtagtgaagc aggagataaa acattaaagt acatacatga
    19201 tgtcattagt aattatctag aaccaggaga attgctttgt cgagtttcta atgaccagtt
    19261 taatgtactt attaaaacta ttcctcaaaa agaaattctt aagtacatag aaaatatcac
    19321 caatgatatt aatagtttca ataaaaatga agaatgtaaa tattttatag ctctatctat
    19381 aggtgtatat aaaattgatg acccaaatct acctttagtt tcaattcaag accgtgcaaa
    19441 tgttgcacga aaaaataata aaggaaacat tggaaatcat ccactttata catgtgtttt
    19501 ttatagtgat ttagagcgtt taaaaatgat taaagaaaaa gaaatggaaa atagaatgga
    19561 ggaagcatta aataataacg aatttatagt atatcttcag cctaaaataa gcctcaaaga
    19621 taatactatt gtaggtgcag aagcattagt aagatggcaa gacccaaata aaggtcttat
    19681 accaccagac gagtttattc ctttctttga aaaaaatggt tttattacaa aactcgacca
    19741 ctatgttttt gaaaaagtat gcagtatgat aagaaaatgg atagataatg gagaaactcc
    19801 aatacctgtt tcagttaatt tttcacgtgc taatttaaat aatatagatt ttttagaaaa
    19861 atacagaatg cttcgtaata aatacaacat tcctgctaag ctcttagaaa ttgaattaac
    19921 tgaaacactt gtatttgaaa atctccaaaa attaattaat ataatagacc aaatccatga
    19981 agaaggtttt caatgttcac tagatgactt tggaagtgga tactcttcac tcaatatgtt
    20041 aaaagaaata aaagttgaca cattaaaact tgaccgtgct ttttttagct cacctaatgc
    20101 agataatatt gctgaaaatc atgtaataga atctatagtt aatttggcaa aaaaattaaa
    20161 tatgaatagt atatcagaag gtgttgaaac aatcttgcaa atggattatc ttaaaaaaat
    20221 taattgtgat atgatacaag gatatgtttt ttcaaaacct ctacctcaag aaatatttga
    20281 gaaaatgact tttggaaaaa aactagaaga aaccagtatg gatagttccg tttaaataaa
    20341 ataaaaaact tgtctctata aaataatttt aatcatttta taaagacaag tctttttatt
    20401 ttccaattta attttatttt ctaaatttct tacactcggc ttgttttaaa ttcccttttt
    20461 aagaataata atacaattat catagcaata aaatctgcaa ctggctgtgc caaccaaaca
    20521 ccatctaaat taaattgaat tggaagtaca atgattaatg gtataaataa aataaattgt
    20581 cttaaaagag ttaaaaacat tgaatgttta actttactta tacactgaaa atacacaggt
    20641 cctacaatag aaatccccat tataggcaat gtaattagat ttaggcttat acctcttact
    20701 gctatatcca tcaaatctga atctttatta aatataccta caaatacttc tgggaaaact
    20761 tgtactacta aaaatccaaa tgacaatatg acaactgaca ctatgataga taatattaaa
    20821 gttttctttg cacgctcata ttgttttgca ccataattgt atgatattat agtttgcata
    20881 ccttgattca atccaaacac aggcatcata aacatcaata aaatagatgt aagtgctgtc
    20941 atagctccaa tagctaaatc tccaccataa acctttagag aattatttgt aaacatgtga
    21001 gttatactta tagctacttc catagcaaaa ggtgtcattc ctattgcaaa taccttcttt
    21061 actatatctt tattcaattt taagttacat ttttttagtt ttaaattgga cttccctctt
    21121 ataaaataat gtattaccca aaagaatact actatttgac agagtactgt tgctatagct
    21181 gctcctttta tacctaaatt aaatacaaat ataaatatag ggtccaatat caggtttaat
    21241 acacatccta caatcattgt ccttgctgct aattttggat taccttctgc cctaattgca
    21301 ttattaagag aaaatgcaac taaattaaat atacttccaa ccaatatgac actcatatag
    21361 tcttttgcat aaaatattga atctttactt gcacccaaaa taaaaagtat atcttctaag
    21421 aaaactaatc ctaatatagt tataattaaa gagataatta tagatagtgt caaagcatta
    21481 cctaatatct tctctgcttc ttctctattt ctttccccta actttataga caatcttgtg
    21541 ctagcaccta ctgataccaa cattccaaaa gctattatta gagtaaatac tggcatagtt
    21601 acaccaagac ctgcaatagc tatagagcca ataccttcca tagaaccaat aaaagctcta
    21661 tctactacat tataaagtga agttaccatc attgctatta ttgcaggtat cgaataccta
    21721 aataataaaa tccatatttt ttcatgtctt aatgcttctt gattctccat gttgtcacca
    21781 tttacaccat gtcataagtt atacaaattg gtttatttgt tcttgggtct gttgctattt
    21841 ctgcatcaat attaaataat tcttttagat tatccttcgt cataacatca tatgcatcac
    21901 cttcacaaac tattttacct ttcttaatac ctatcatgtg gtcagcaaat cttgctgcat
    21961 tattaagttc atgtattacc atgacaatag ttcttccttg ttttttattt agttcatcta
    22021 ataattttag tatctccaat tgatgtgcca aatctaaata tgttgtaggc tcatccagta
    22081 ataatatatc agtttcttgt gccaaagcca tagctatcca tgccctttgt ctttgtcctc
    22141 ctgataaatc ttccatattt ctatccttaa attctgcaat tccagtaact tctaaactcc
    22201 aatttacaat ctctctgtct tctttactag aattaccaaa tccactttta tgaggaaatc
    22261 ttccataaga aattaattct gaaacggtaa gaccactagg agcttgaggg ctttgtggaa
    22321 gtacagccat atcttttgct atttctttag acttcttttt gtagatgtcc tctccattta
    22381 tatatatttt cccactatta gggctaataa ttctacctat agttttaagt attgtcgatt
    22441 ttccacaacc attagcccct atgatggtag ttatttttcc ttttggtata tttaaattta
    22501 aattttttat aatatctgtg tttccatatg atacatttag attcttagta tttatacagt
    22561 tcataacaac accctttcct aatcatttac caacattaaa taaataaagt acggcactcc
    22621 tattatagaa actactatac ctactggtat ttctataggt gctagaagat ttcttgatat
    22681 agtatctgct attaaaagta ataatgttcc tatcaatgct gatactggta ttaatctttt
    22741 atgctttggt cctattattt ttctacctat atgtggagct attaaaccta aaaatgaaat
    22801 actacctgct actgctgtcg atacaccaga taaaattact gcatatatta taagtcttct
    22861 tctttgtttt tctacatcta caccaagact tatagatact tcatcaccca aatttaaaac
    22921 atctatatat ttagatttat aaatagttat acccataaaa atcactataa atggaagcac
    22981 agctattaca tatttccaac tggttcccca aatgcttcct gatgtccatg ccataaccct
    23041 attaaattcc tgtgttgtaa atttcaattg gaatattgtc aaaattgaag taaaagctat
    23101 gtttacacct ataccaataa gtagtaatct tgatgaattt ataccacctt tccatgcaag
    23161 agaatatata agaaatgctc caaataaagc tcctataagt gcaacaatag gcattgtaaa
    23221 tacagtcaag ttactcatac cttcatatac attaccattc ataaggtata tataaactac
    23281 tacaaacaat gcagcacctg aatttattcc caaaattcca gaatcagcta aatcattctt
    23341 tgtaactcct tgaagtatta cacctgctgt tgataatgca gaaccaacca aaagtgctat
    23401 tactattctt ggtaatctta atttaaatat tgcaatttca tgattacgct gaccctgccc
    23461 taaaaaagtc tttataacat ccattggttc tatagaaaat gagcccatat ttaaactcaa
    23521 taaaaaagtg ataaaaataa gcaccattaa aattgatata acaagtaatg ttttagaatt
    23581 tatttttata atatttttca tagtacctat ttctccccct ttctaacaag gtatataaat
    23641 attggcactc ctataagtgc tgttatagaa cctactggtg tctcatatgg aggatttatc
    23701 atcctactta atatatctgt atatacaagc aatacagctc ctaatactaa agagctcggt
    23761 attatatact tataatctga acctactatt cctttagcta tttgaggaac tataagacct
    23821 ataaaaataa tattaccaga cactgacaca gatgctccag tcattaatat tacaagtact
    23881 atacatataa atctaacaaa gttagttttt tgtcctaatc ctattgccac ttcttctcca
    23941 agacttaata tagttattct tggagccata ataatagcta aaataaatcc aataccacca
    24001 gctacaaata gcaattttat accttcccac ttcactccta caagccctcc tgatatccag
    24061 aaacttaatt gttgagatag gttaaaatac atagatattg ctgatgccaa agaaattagc
    24121 aatgtaccaa gagcgactcc tgcaagagct aattttacat tattaactct tcctcttgat
    24181 ttagaactta taaaatatat aaataatcca cttatacttg ctccaataaa tgcaaacatc
    24241 attacactaa aacttccatg tataagttga ggaagttttt tttgaagtac cagtgatatc
    24301 gaaattgcga atgtagctcc ttgtgtaatt cctataacag atggttcagc tataggattt
    24361 ctcgttattc cttgcattat tgccccagaa actgctaaaa atcctccaac aagtgcagct
    24421 gctattgccc ttggaagtct aacatccttt actattctca tatttattcc atcttccatt
    24481 tttatcaaac tatctataac agttgataga ttcatatctt ttgccccaat agttatggat
    24541 aatacaattc caaatacaag tacaactata cttactaata tcaacaaata agttatattt
    24601 tttttactca gcttagtcaa ttatcctacc tccttttccc ttttaatcgt cagtataata
    24661 tcatctatta agtattttaa ttttaagatt tattaaaaat aggtgtgaaa aatgaatatc
    24721 attatctcac acctactaag ttaagaatta ctttgttaat tcatttttaa ctgattctaa
    24781 taataactct tttccaattg gattgtatga ttgactgaaa aatggagcag catcaagtat
    24841 tgttacatta ccatctttta ctgctcttat ttgagcccag atagcactat tttctaaatc
    24901 ttttttatct gcttctgtag caattacaac tatatggtct gcatctatat ctgttaaacc
    24961 ttccatactt accattggta gtgttattcc atcctgtttt ggcatattct taggtttagc
    25021 taatttcata tcatcattga ttagagtacc tattccacca tcactaaata ccataaattg
    25081 acctgaactt gccaacactg gtaaataagt tttttctcca ttcttttcta taacttcctt
    25141 acctaacttt gtagcttttt catcatactt ctgtagccaa cttttagctt cttcttcttt
    25201 gtcaaataac tttgaaacat cagttaactt gcttctccag tcatttgcat aatctttcat
    25261 cataactaca ggagctattt cttttaattg gtcatatatt ttttcttgtc tttgactcat
    25321 tattattaaa tcaggattta cttctaatat agcttccata tccatagtat ccatcattga
    25381 gtgcccaact atctttacac ctttaagctc ttctcttatg taacttggta atttatcagt
    25441 ttcatatgag tctacatttg ctgttgcaac aggcttataa cctgctaata atagttcttc
    25501 actacttcct gatatatcaa ctattttttt aggatttgat ggtatcttaa cctctccttt
    25561 aacagattgt acaactcttg tctctgattt atctttatcc tctgtattct tatctgaaca
    25621 tgctgtaaca agtactaacg tagttataat agatataaat attgcaagtg attttatttt
    25681 tttcatgatt acttctccta cttgtttatt atacttacat gatattgatt atcataagca
    25741 catatttatt atagcatttt tctattttta gtcaatatta ttttgtaaaa ggataaaaat
    25801 tcctaattaa tcttaattat atatagctta gataaggttt tcttatatta aacagtattt
    25861 ttttaaagaa ttggacacaa atacaatgac ttttcagtta aacaatgata aaatgcaatt
    25921 tatagataat gaatttagta aggaggattc aaaacatggt acatttagta tattgtgata
    25981 atgcaggaaa aaaaggagaa aaggtcttag ataaaatctt ggctggaaca aaaacaatgg
    26041 ttattagagg tgctgctggt agaaaaatac cacatagtag agtatttgaa gatgagttac
    26101 tttattttat ggaaaaagga actgcaaaaa tatctgcaaa agccactgtt aaaaaggtag
    26161 aaaactatgt taaattaaca gaagatgaaa tttctaaaat tttaaatgaa aatcaaccaa
    26221 aattaaattt atctgaaaag caaaaagttc gttggcataa aaaatgttta tgcttagttg
    26281 aatttgaaaa tgttgaagaa ataacacctc ttgattttga ccatcaagga aatatggatg
    26341 attggcttat tgttgaaaaa attgaagatg tagttgttgg tactagtata ccttacaatt
    26401 atgagaagtc taaattttaa agtatcaata acataatact atattgctaa actctactta
    26461 aataaaaaaa gagtgcattt aataattata aaaattattt ttatacactc ttttttaata
    26521 ataattttaa attacttact ttctaatctt tcatatacat ctataaattc ttctgctaat
    26581 tgttgaaaat tcatagctgt cattaaatgg tcttgtgcat gaataagtat aacacttatt
    26641 tcagttttat taccattagc ttcattttgt atcaattctg tttggaattt atgagcttta
    26701 tgaattgatt ctttcgactt ttcaatacat tctctagctt tatctatatt cccgctcttt
    26761 gcttctttta ttgcttcaaa tgctagccct ttcgcatcac ctgcaaatcc aattattcca
    26821 aaagatatct ctatcatctt ctcatccatt tattcgacct cctaaatatc tctatagctt
    26881 gatatgacta atccattctt ttctaaaaat tctttgactt ttttagatgt aagtatcttg
    26941 tgctctttcg ttctatcaat agcataagat gtagaattta aaatataatc atctaaaaaa
    27001 gctgggtgag acataatatc cactacatca tacttcatta tttcgtctat attttttata
    27061 aaatattctt cacttacatt ttccttataa aaactatcta ttaaaggaac tactttagaa
    27121 tactctaaat tatattcaaa tccacctctt attggaagat tatacttggt tacaatcttc
    27181 tctattactg gctttaaact taataaagta tggatatgat ggtgactatc taaatgagat
    27241 atatctattc caagcccttt taccctatct atttgagcac aaagttctct ataaatctca
    27301 tcacaatcca ttttttcaat aatttcgtct gtaatcctcc taataaaaaa accgtcttta
    27361 tcaacaatag tttttaagtt agataataat ggtctaccac aacttaaagt catatgaact
    27421 ccacaattta aagttttatt ttctttaagt aagcctactc catgttctac cccaggcata
    27481 tttgccatca tagaagtaga cctaactata ccattattat gagctgaaat tattccatag
    27541 ttcacagctt cacaatatcc aaaatcatct gcatttatta taattttagt cataccataa
    27601 cctactttct atagacaact atctattaaa tctaggaaga taatctttat gagcttccaa
    27661 catttcgtct aatatagttt ttgctaagtc atcagatgga atcaatgggt ttatacaaag
    27721 tgccaaaaga gcagattcat aatcgccata tacagctgct ttagctgcca atacttcaaa
    27781 tgatttgatt tgacttacta atccatgcac agaatctggt aaatatccta tacttattgg
    27841 ttttggacca ttttttgtta ttacactact tacttctacc gcttgttcat ctttaaaatc
    27901 tcttatagaa cccttattta atgtattaac tacttggata tcttttttgt cgttgtatat
    27961 agaacttatt aaattacaag cagcatcact atagtaagcc cctcctcttt tttcaagttg
    28021 aggtggtttt acatctaatt tttcatcctt atataattca aataattgtt cttccaattc
    28081 tttaactact tgacctctag cttttccctc tttaaactct ctcaactcat cctcaagcat
    28141 ttctttagtt ttatagtagt atctatgata tggacaaggt attgcaccca aagattttac
    28201 aaattcagca ttaaaatcaa ttgcctttat attttgcata cttatatctg ctttgacaaa
    28261 tttatcaatt gcttcttttg taacatcttc tccatctaaa gatacattta gaccataaac
    28321 catatgatta agacctgcaa aatccatact tattctgtca ctttctacat taaatagttt
    28381 ggcaacatca ttttttaaat gaattggcac gttgcataga cctatatatc ttctaaaatt
    28441 agtatatttg aatacagcct ctgttattat tcctgttgga tttgtaaaat tcaccatcca
    28501 tgcatttgga cataattctt ccacatcttt tattatatca aatataactg gtattgtgcg
    28561 aagggcttta aataaacctc cagcaccatt agtttcctgc cccataactc catgagataa
    28621 aggaatagtt tcatctttta ttctcgcatc taaaagacct actctaagtt gtgttgtcac
    28681 aaagtctgca tctcttagag cttctcttct atctaaagta agatttattt tcatatctac
    28741 tccagctttt tttaccatcc tcttagctag atttccaact atctctaatt tttcttttcc
    28801 agcttctata tctacaagcc ataattcctt tacaggtaac tcttcatatc tatttataaa
    28861 accctctaca agctcaggag tataacttga acctcctcca attgtaacta tttttagtcc
    28921 ctttttcatc tcattatacc atccttacct ataatttaat atactctaca aaaccccata
    28981 catttattta aaactctata catttattta ccgaaataaa actacctagt tgttaatttt
    29041 caatttatta gcttccattt tttcagacgc tatgacaaat ggaatatata ttaatattga
    29101 taatattaaa ttaaatagtg ctaaagctcc accagtccag tcacctgtag ccattgctcc
    29161 acctaatata ggaggtgtta cccaaggtat tttaggtaaa attactggtg ctactaatcc
    29221 aaaatctatt gctaagtatg atacagcact acatattact ggtgcaagta caaatggaat
    29281 cataaatata ggatttaaaa ctattggaag tccaaatatc aatggttctc ctatgttaaa
    29341 tattgcaggt ggaccaccta atactatcat ctctttacgt cttcttccag ctattaataa
    29401 agctactatt aatcccaata ccattccaga accacctaaa tatacaaatg catcaaagaa
    29461 tgcacctgca agtacatggt atccttccgt tgctcctgct tgagccaagg cagcattttc
    29521 tccacctaat ttcataagta tagtttctgt aaaaggaagt gctatatttg caccatgaag
    29581 tccaacagtc caaagtatat gaattataaa tgcaataagc attgtagaac ctagactatc
    29641 agctacattt gatagtggtg ctcctaaata agtatttaaa atatctgtta agaaacttcc
    29701 attagaaagc atttttataa atattcctat tacagtaaat atcattatag ttaacattcc
    29761 tggtattaac tttgcaaatg atcttgaaac tgctggtgga actccatctg gcatttttat
    29821 agttaatttc tttaccttag ataatcttac aaatatctca gttgataata atcctattaa
    29881 tatagaagag aataaagctg ctgtacctaa gtaggtttgt tgtatcattc cccatccttc
    29941 aactactgta gttcctccct caggaactat tttaccaatt tgtggagcca ttataaaaaa
    30001 gatagataaa gctataagcc cagattgtaa cccatcactc tcataagatt ttgctagaaa
    30061 ataagcaaca cctattacta agaatactgc cattgtacct attgctcccc accaaaggtc
    30121 gcctccaaat gtggtccagt tttctccaaa tatacttgcc atcaaatttt tgtatgcttc
    30181 caatggtaag ttatttatca atgttcccaa tgcacctacc atagttatag gtatcattac
    30241 tataaatgca tctcttactg ctactaagtg cctttgagct cctattttag cagctacagg
    30301 cactatatat ttatccataa atgacatgaa tttttccatt ttacatcctc cagtacaact
    30361 ttattttgaa ctatttaact ctacagctct atctaacaca gcttttccat tacatcttcc
    30421 ataatccatc atatttataa cttctactgg aatattatat ggttttgcca tttcagttgc
    30481 ttttcctaat acatatctaa cttgaggccc taaaagtaag acatcacaat tttctatttc
    30541 attttttaag ttcacttctg atatagccca tatttttgct tctataccgt tttcctttgc
    30601 tgcatcctcc atttttgtaa ctaataaact agttgacatt cctgctgaac aagctaacat
    30661 tatttttatc attttttccc ctccaaatta gattcattaa atatttttta agtcataagt
    30721 tttttaaact atacatttaa aatatgtttt tctattaatt ttttcttaat gtatatatct
    30781 tatttttaaa tgtatataca tttaattctt gatattatta tataccaaat gtatatacat
    30841 ttcaagaaaa ctttttcatt ttatttaaat tttattcgac aacagcattc aaagttaatg
    30901 tatatccata gtgatatgtg tgtgagtact caaaaatctc actattttgt aacttacaaa
    30961 tttggcttat atataaaagt ggctctggtt cttctaattt tagattatcc atacactctt
    31021 cattcgatat tacagcttgt acttctctct ctgacatggc tatcttgtat ccacacactt
    31081 cttcaacaaa attataaaga gaattttcac aatgagtctt atttaaattt ggaaataact
    31141 taactggcat ataagtaatc atatatgaaa ctcttacatc attagctaat cttactcttt
    31201 ttatttccca aacattttct tctaaactta tattcaactt acttgataaa ttttcatctg
    31261 cctgaactat ttcaagagat accaatatat tagatacttt atagccttta ctttccatct
    31321 ctttagtaaa tccacttaca gacgatatat tatcatatat attatttgca ataactatac
    31381 tacctacacc tctttgtcta gttatatagc cttctttaac tagattatta agtgcagacc
    31441 ttacagtcat tctagttaca ttaaattctt cactcagctg tttttcagaa gggattaaat
    31501 ccccttcttt caaactgtct gaatttatta actctctaac atgattttct ataactttat
    31561 aaattggctc tttcatttaa ttcactcctt attaaatctt ttatataata agataatttt
    31621 atatacaaac aaagaaaatg tctatacatt taagataatt taaattttat tcagaaatct
    31681 tgtacaactt tccgagtttt aataaagata taaatagact tatcattaat atacctttta
    31741 atatacttga taaggttata ctccaccata caccatttag acccaacatt tctggtctag
    31801 atataaagta agccaatggt actcttgcac cagtcagtat agtaattata atagaaggta
    31861 tataggttct ccctaatcct ttgaaagctc ctgttgttat tatttctaaa cacataaaaa
    31921 attgagaata gcctaatatt ttaagataaa ctgctccttt ttctattgcc tcactttcat
    31981 ctataaaaat agaaaatata ctctctcctg caaacactaa tactaaagta gttattatac
    32041 caagtacaga agatacagtt atagctattt tgcaaccttt atttattcta gaatacttct
    32101 tggcaccata attttgtcca acaaaactgc ctaatgcaac tgatagccct tcagccgtca
    32161 tccaggaaat tgcttctatt tgtgagccta ctttttgtac tgcaacagcc acaggccccc
    32221 atgatgctac tattactcct aatagcattg agaatactgt aaacatacca ctttgtattg
    32281 ctataggtaa tcccaattta tacagaactt tataatattt agtctctatt tctttaaata
    32341 gtcttaattt aaaatattct tctttacttt taactattat atatataaaa catgtagtaa
    32401 ctactatctg agcaaataca gttgcaatag cagctcctgc aacaccaagt tttggagcaa
    32461 atccccatcc aaaaattaat atagggtcaa gtataatatt agttattaat cctactgtat
    32521 taatacgaaa aggagtttta ctatttccaa gaccattgaa aattgcagta aatactggat
    32581 taataaaata aaataccata cctagagcta ctattatcaa atactgtcta gacatggtta
    32641 taacttctaa gtctcctaat ctaaaaaaac ctatcaattg tttattaagt actattaaag
    32701 aaattgtata tattattgct agtataatat ttatttctat tgctgacttc atatatgatt
    32761 tagtagtgct tatattattt gcaccaatac tttgtgctac ttttatctct ccacctactt
    32821 ttgaaatcat aataaatgcc attgcaagcc atggaaaaaa accagctgtt ccaactgcag
    32881 ctactgcttt acttccggct ttaccaaccc atatcatatc tatcatgtta taccccatct
    32941 gtataaatga agtccccatt attggaagtg atagcttaag taatttttct gtaattcttc
    33001 cttctgttaa attaagtctg tctttcattt tccacctctt ttatattaaa tttatttgct
    33061 tatatagcta gattaatcat tttatttgat tgagttcact atccttcaat ttatattatc
    33121 atatctcagg attgcatctc aatcatactt atgtttaaga tacagtattt tacctatcta
    33181 tgataaaatt aatacttatg aatataaatc tagccatttc atcaatacat attctaacct
    33241 ttaacttaac ttcaattaag tatacatatc gtaaccaatt agaatatttt atacggtatc
    33301 ttccattaat aaacaaccaa tatcaatgat ttatatataa ttttatttat acataaaata
    33361 gtatactata ataataaaaa aactatattt gaatgcttta agcatgttta ctaattgtaa
    33421 tttccacaca aatttgataa tatatgaata tattatggtg aaatttatag atatatatta
    33481 attatgggga gattgtggga ggttcttttc acaagacatt taagctatga aaataaataa
    33541 aaaattcaat agagttgata tgcaggtttc aatacttact gcaattattg taataatatc
    33601 ttcctcatgt gtatattttt ttaattatac actaacttat aagagcatga tatactcttt
    33661 aagtgagagg tcaaaacata tctatgaata tgtagaaaga aatattgata aaaatacctt
    33721 tactgaaatt aattctaaag aagaccaatc aaaaaagtct tataaaagtt ctaaaatcct
    33781 tttagaatct gtaaaaaata ctactggagt catgtatcta tatactgcta aaaaaacaaa
    33841 agatggatca ctagtatatg ttgttgatgg tttaaattca tctaggagtg attttagaaa
    33901 tgctggtgat ttgatagaaa aagagatttg gggagacctt aacaaagcat tagataatca
    33961 tatattgtta cctaaaaaga ttaaatcaac atcttgggga tacatattta tatcgtattt
    34021 tcctattcac aatgatgttg gtaaggttgt tggagtaata ggaattgaat ttgaagcaaa
    34081 acatcaatac aatacattta aatttataag tatagttaca ccaataatag cattattaac
    34141 ttgtctaata tcagcattga ttgcagtgat tctatttaaa agaatatcta atcctacata
    34201 tactgatttt gctaatacag attatttaac aggcctaaaa aatagaaatg cttttgaaat
    34261 agatatgaat aacttaaaca attcaaatct aaagaatcta atatctatca tatcaataga
    34321 tttagacggt ttaaaaaaga ttaatgataa atttggccat cagacaggag acttatatat
    34381 taagcaagca agtaaaatta tacaatatgt aataaataaa aaatatatag tttatcgtat
    34441 tggaggtgat gaatacataa tta
//
LOCUS       DAEHWO010000038        34315 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEHWO010000038 DAEHWO010000000
VERSION     DAEHWO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.038"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            68..1627
                     /locus_tag="KNP54_002180"
     CDS             68..1627
                     /locus_tag="KNP54_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0893078.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGESKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            1733..2692
                     /locus_tag="KNP54_002181"
     CDS             1733..2692
                     /locus_tag="KNP54_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893079.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPAYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLAKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            2695..3507
                     /locus_tag="KNP54_002182"
     CDS             2695..3507
                     /locus_tag="KNP54_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893080.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(3723..4625)
                     /locus_tag="KNP54_002183"
     CDS             complement(3723..4625)
                     /locus_tag="KNP54_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0893081.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            4980..6158
                     /locus_tag="KNP54_002184"
     CDS             4980..6158
                     /locus_tag="KNP54_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBF0893082.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVRLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            6167..6823
                     /locus_tag="KNP54_002185"
     CDS             6167..6823
                     /locus_tag="KNP54_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBF0893083.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            6823..7488
                     /locus_tag="KNP54_002186"
     CDS             6823..7488
                     /locus_tag="KNP54_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBF0893084.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            7593..8369
                     /locus_tag="KNP54_002187"
     CDS             7593..8369
                     /locus_tag="KNP54_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBF0893085.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            8431..9765
                     /locus_tag="KNP54_002188"
     CDS             8431..9765
                     /locus_tag="KNP54_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBF0893086.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            10261..11193
                     /locus_tag="KNP54_002189"
     CDS             10261..11193
                     /locus_tag="KNP54_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBF0893087.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPNNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNNNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVAT
                     KKSQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSE
                     GHRKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(11585..15124)
                     /gene="nifJ"
                     /locus_tag="KNP54_002190"
     CDS             complement(11585..15124)
                     /gene="nifJ"
                     /locus_tag="KNP54_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBF0893088.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPVNT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMGICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(15642..16211)
                     /locus_tag="KNP54_002191"
     CDS             complement(15642..16211)
                     /locus_tag="KNP54_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBF0893089.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(16283..16891)
                     /locus_tag="KNP54_002192"
     CDS             complement(16283..16891)
                     /locus_tag="KNP54_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0893090.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            complement(16899..18662)
                     /locus_tag="KNP54_002193"
     CDS             complement(16899..18662)
                     /locus_tag="KNP54_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBF0893091.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(18705..19172)
                     /locus_tag="KNP54_002194"
     CDS             complement(18705..19172)
                     /locus_tag="KNP54_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893092.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            19356..19817
                     /locus_tag="KNP54_002195"
     CDS             19356..19817
                     /locus_tag="KNP54_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893093.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKV"
     gene            complement(19910..20080)
                     /locus_tag="KNP54_002196"
     CDS             complement(19910..20080)
                     /locus_tag="KNP54_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893094.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(20269..20490)
                     /locus_tag="KNP54_002197"
     CDS             complement(20269..20490)
                     /locus_tag="KNP54_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBF0893095.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(20574..21800)
                     /locus_tag="KNP54_002198"
     CDS             complement(20574..21800)
                     /locus_tag="KNP54_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBF0893096.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            complement(21862..22794)
                     /locus_tag="KNP54_002199"
     CDS             complement(21862..22794)
                     /locus_tag="KNP54_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBF0893097.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            complement(22883..23410)
                     /gene="hpt"
                     /locus_tag="KNP54_002200"
     CDS             complement(22883..23410)
                     /gene="hpt"
                     /locus_tag="KNP54_002200"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBF0893098.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            23639..24715
                     /locus_tag="KNP54_002201"
     CDS             23639..24715
                     /locus_tag="KNP54_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBF0893099.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(24801..26009)
                     /locus_tag="KNP54_002202"
     CDS             complement(24801..26009)
                     /locus_tag="KNP54_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBF0893100.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(26170..26559)
                     /locus_tag="KNP54_002203"
     CDS             complement(26170..26559)
                     /locus_tag="KNP54_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBF0893101.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            complement(26663..27664)
                     /locus_tag="KNP54_002204"
     CDS             complement(26663..27664)
                     /locus_tag="KNP54_002204"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBF0893102.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     misc_binding    complement(27723..27978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(28112..29302)
                     /locus_tag="KNP54_002205"
     CDS             complement(28112..29302)
                     /locus_tag="KNP54_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBF0893103.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEISRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     gene            complement(29583..30704)
                     /locus_tag="KNP54_002206"
     CDS             complement(29583..30704)
                     /locus_tag="KNP54_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBF0893104.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            complement(30765..31250)
                     /locus_tag="KNP54_002207"
     CDS             complement(30765..31250)
                     /locus_tag="KNP54_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBF0893105.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            complement(31252..31920)
                     /locus_tag="KNP54_002208"
     CDS             complement(31252..31920)
                     /locus_tag="KNP54_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893106.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            32310..>34315
                     /locus_tag="KNP54_002209"
     CDS             32310..>34315
                     /locus_tag="KNP54_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893107.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKI"
BASE COUNT        11904 a         5532 c         4368 g        12511 t
ORIGIN      
        1 ataatgatta ctattataca ataaaaaata tgtgttaaat attattttat ggaggtttta
       61 taagaatatg aaatttaaaa aattggcatc attaatctta gtttcatcat taatgcttac
      121 atttacagcc tgtgcttcca atgataaaga caagtctagt ggaagcaaat ctggtggaac
      181 tgttgtaata cctatggcaa gtgacccaga tataatcaat ggagcttttg caaacgttaa
      241 agaagactct cttgcatcaa atatagttta tgctcctctt tatacttatg aaaaaggaaa
      301 tttagtaaat tatttagcag aaaaagtaga ttttaaagat agtaaggaat taactataaa
      361 attaaaatcc aatttaaaat ggcatgatgg aaagccaata actgctgaag atgtcttatt
      421 tacatttaat acagttttag acgaaaaaca aaattcacca tcaagacaat acttattggt
      481 gggtgagaaa ccagttaaag tagaaaaaat tgatgattta acagttaaga ttactttacc
      541 aactgcaagt gaatctttct tatatggtat atctaaaatt tctccaatac caaaacatgt
      601 gtttgaagga gaatcaaata tagctaagtc agaaaaaaat aataatccag ttggttctgg
      661 tgcattcaag tttaaggaat ggaaaaaagg tgaaagcata gtatttgaaa agaatgcaga
      721 ttattttggt ggagaatcta aggcagattc tatagcgcta aaaataattc ctaatgaagc
      781 atctcaagaa gcagctttaa ataatggcga aatttcactt atgaagacat ctgctgaagg
      841 atatgaaaag gcaaaatcaa actcaaattt acaaacttat acttatagtg aagaaagatt
      901 aaactacatt gtatttaacc aaaatatatc aaacatggct aacaaagaag taagacaagc
      961 cttatcatat gccttaaata gaaatgaaat gatagaatca gcatatggaa aagaaggttc
     1021 tgtacctgct aaatctatat tagttccaga agcagacttc tatacagaag aaggtgttga
     1081 aggatatgac caagatacaa ataaggctaa agacttattg gataaaagtg gtgttaaaat
     1141 tgataaatta aaaataggtt ataacacagg tagatttggg cataaaaact atgccttagt
     1201 agctcaacaa gagttgaaaa aaattggtat agaagctgaa atagttcctt atgaaagtaa
     1261 ggcattcttc aatatactat ttagtaatag cactgaatgt gatatgtatg taaatggtta
     1321 tgcttgggga ttagaaccaa acccatatag aggtatgttt gaaactggtc aatattgcaa
     1381 ccaaactaaa tattctaatg ctgaaataga tgctttatgg gaaaaaggat ttactgagtt
     1441 aaacaaggaa aaacgtgaag aaatatataa gcaaatacaa caggatatat ctaaggatgc
     1501 gcctatttac actatagatt atgaacaaaa tttaatggca gctcaaaaaa atctaaaagg
     1561 aataaaagat gctaaaccat ctcctgcaat attatttgaa gattggtcta aactgtatgt
     1621 agaataattg atgtaaaatt ttatattatt aattagaaaa ggagatgtct aaaaataata
     1681 ttgttttatt attttaaaac gagacatctc ttttaattag gagaatttac ttatgttaaa
     1741 attaatattg aatagagtaa aagttttaat acctatgtta atcttaatat ctatattatc
     1801 atttggactt ttagaattag ctcctggtga cccagcagat gcatatataa atcctttaat
     1861 gtcttcacag gatattgaaa atataagggt taatatgggg cttgataaac cagcatatat
     1921 aagatattta aactggttga aaaacacttt aagtggaaac ttaggtattt cttatataaa
     1981 ccatatgccc gttacagaac aaattatgga aaaaatggga aatacattta ttcttatggg
     2041 tacttctttg atattttcaa tattggtagc catacctctt ggaatatttt tagctgtaaa
     2101 taaaaattca ataactagta aagtatcatc tgtttttaat tatataggtg tttctatacc
     2161 ttctttttgg ataggtatga tactcatttc aattttttca gttaaactta acattttccc
     2221 atcaggaggt atgcatacta ttggaaatga tagtattgga gatttagcaa aacatttagt
     2281 tttgcctgta ataactttag gtctatataa tactgctatt tttacaaatt atgtagaagc
     2341 tagtgtaaat gaacaattaa aaaaacaata tgttattaca gcaagagcaa aaggattatc
     2401 agaaaaagtc atactattta aacatgtctt gaaaaattca ctgacatcat tggttacaat
     2461 cctaggcatg agtatacaaa aattagtcac tggtgcattt gttacagaag tagttttctc
     2521 ttggccaggt atgggaagat taatgattga ttcaattttt tcaagagatt atactgtaat
     2581 tatggcaata actatgttat cagcactatt tttaatttta ggtaatttag ttgctgatat
     2641 actatactta ttaattgacc ctaaaataaa atctagcaaa ggaggattct agttgtgttt
     2701 acaagtatct taaaaaaatt aaaaaaagat aaatcctttg cttttgcatg tattactctt
     2761 agcataataa tcatattaat tatagcttct tttatattaa atatagactc taatgcaatt
     2821 gatactactt ctaaacttca agaacctagc ttaaagcata tctttggtac agacgaactt
     2881 ggtagagatt acttctctag agctctttat ggtggaagga tttcacttag tgttggtatt
     2941 ttatcaatgc ttatttctgt agtatttggt actgctgtag gtgttattag tggatatatt
     3001 ggaggtaagc tagaccaatt cttgatgaga ttagtggata tgcttatgag tataccaagt
     3061 ttcttagttt tgattgtatt aaatacttat ctaacaccta aagtttccac tattatacta
     3121 attattggat tcttaagttg gatggaagtt tcaagaattg tacgtggcga aacattaaaa
     3181 ataaaggaaa atgaatactg tctagctgct aaagctactg gtatcaaaac tagaaatata
     3241 ctattaagac atatagtttt aaacttaaaa gagactattg tagttgctgg ttcgttaaat
     3301 attgctaatg ctatcttaac tgaatctgct cttagttttt taggtcttgg aatccaattg
     3361 cctcttgcat catggggtaa tatgcttcaa gatgctcaaa gacatatttt tgacaagtta
     3421 tatttagctg tatttccagg attacttata tttttaacag tcatgagttt gactataata
     3481 agcaaaaaat tttctagtaa tacttaacaa attttatata gaaaataaaa acagtgatta
     3541 tctaaagata tacactgttt ttatttttcg tttaaaaaaa tacatatttt gtatattata
     3601 actttaaata ctactctacc atgttatgca aagcgtatta ttgctctcaa acatatagat
     3661 gaaaaactaa tagtttatta taataaaaat tgatttattt atttgttatt ttaataacat
     3721 ttttaagagt tctttttact aaagaaatct ataataaatt taaatacatg ttggtctaca
     3781 tggctataac gttctttttt aggtctacat aatataactt tccatgtaat aggatgatta
     3841 aaaggctttt ctataatttt gctattttca aaaaaatcat gaactggtga tggtaaaatt
     3901 gttataaaat cagaatttgt ggttgatagc aacaaaaaat cccatgaacc agacattata
     3961 tatcttttta acttaacatt ttcatcagta aatttttgca ttagcttatg atgtatcata
     4021 aaagtaggat taaatattgc aagtaactgc tcattcaaat cgttccaatc tatcttatcc
     4081 ttcttagcaa gtggatgatt tatatttaaa aatgctgtaa gttcatcttc ttgaagcaca
     4141 tgttcagtta ctacactttt atcaatttta tgtggatgta acaatactgc ataatctaat
     4201 tcctgtaaga taagcattct atttaagtca tatgcaccct tctctactat atcaaattct
     4261 atatctggat tatttgcaac taactgtgca actacatctg aaaatgctat tccaagtata
     4321 agtggaggta ttcctattct aacttttcct ttaaattgaa ctgaatcttc tcttaaatct
     4381 tccatcatat ttttgtattc atttatgata tgttctgcat ttacataaaa tctttctcct
     4441 gctggtgtta acccatttaa cctgccttta tacctttcaa ataaatatac atcttcactt
     4501 tcttcaaaat tttttataat ttgacttaat gctggttgag atatgtgaag tgtcttagat
     4561 gctattgata aattaaaacc agatttcact atttcaacaa aatatttcaa ctgttttata
     4621 tccattttaa acccccttcc ccaaaagtat aatttagatt atattttttc ttctaatgat
     4681 attttatagg aaaatcaaca taatttcatt aatattttaa caaaatattt ttctaaatct
     4741 actataaatt tttatcctat aaatttttct tatacactat ataaaaaatt agacttagac
     4801 aaaacgcttt tttcgccgta atctataatt agaaacagga aaacctaaag cattaggaat
     4861 aaaagtaatt gaaatactta aaaacaagct tgtattaaaa aagtacttta ttatagtgtt
     4921 ccctaatttc tttattcaga aaatttttaa ttatcattca agaaaggtaa ctattagata
     4981 tgaaagatgt agtaatcgta tcagcagtca gaacacctat aggaagtttt ggaggtgtat
     5041 ttaaaaatac ttcagctgtt caacttggaa ctatcgctgt taaagaagcg atatcacgtg
     5101 taagacttaa tttatctgaa atagatgaag taataattgg aaatgttctt caaacagggc
     5161 ttggacagaa tgttgctaga caaattgcta taaatgcagg tataccaaat tctgttccaa
     5221 gctacacagt aaataaatta tgtggttcag ggcttaaaag tgtccagcta gctgcccaat
     5281 caatcacatc tggtgaaaat gatgtggtaa ttgcaggtgg tactgaaaat atgagccaag
     5341 ctccttatat cgttccaact gctcgctttg gtagtaaaat gggtgacata accatggtag
     5401 atagtatgct aacagatggc cttattgatg ctttcaatca gtatcatatg ggaataactg
     5461 cagaaaatat tgcaactaaa tttgaattta ctagagaaat gcaagataaa ttggcattag
     5521 aaagtcaaaa taaggctgag aatgctataa aaaacaaccg ctttaaagaa gaaatcgttc
     5581 cagtagatgt tttaatacgt cgaggaaaaa tagaaactat tgataaagat gaatatccta
     5641 aattaggtat gacatttgaa ggtttatcta aacttaaacc tgcattcaaa aaagatggta
     5701 ctgtaacagc tggaaatgcc tcaggtatta atgatggtgc ggctatgtta atactaatga
     5761 gccaacaaaa agcagacgaa ctaggtatta gaccacttgc taaaataaaa tcctatgctt
     5821 cagctggtgt tgaacctgaa gtcatgggta ctggtccaat ccctgcaact agaaaagcac
     5881 tgaaaaaagc tggacttagc atcaatgata tagacttaat agaagcaaat gaagcgtttg
     5941 ctgcccaagc attagctgtt aaaaatgaac ttcaaataga ttcatcaaag ttaaatgtta
     6001 atggtggtgc aatagcatta ggacatccaa taggagcaag tggagctaga atacttgtta
     6061 ccttaattta tgaaatgcaa aaacgtaaag ttgaaactgg acttgcaaca ctttgtattg
     6121 gtggtggtca aggaatatca atggtggttt cacgatagga ggaaatatga ataaaatagt
     6181 tagcattgat gaagctctat ctcatgtaaa agatggagat acaataatgg ttggtggatt
     6241 catggccaat ggttcaccag aaaatttaat tgattattta tgtagtaaaa atataaaaga
     6301 tttgacacta atttgcaatg atactggctt tattgacaaa ggagttggca aaatggttgt
     6361 aaataagcaa tttaaaaaga taattgcttc tcatgtagga ttaaataaag aaactggaag
     6421 acaaatgaat aacaatgaaa cagatgttga gttagttcct cagggaactc ttgctgaaca
     6481 aatacgtgca gctggttatg gtctaggagg tatactcaca ccgactggta ttggtactct
     6541 tgttgaggag ggaaagcaaa aaattgttgt cgatagcaaa gaataccttc ttgaaaaacc
     6601 aatttatgca gatgttgctc ttctatttgc atcaaaggtc gataaagcag gtaatctagt
     6661 ttataaaggc tctatgaaca attttaataa tttaatggca tctgctgcca aaattacaat
     6721 agttgaagca gatgaaatcg ttgaaattgg tgatattgac ccaaatgaag ttaatacacc
     6781 aggtattttt gtgaattaca tcgttgaagg aggtaattta taatggataa attagaaatg
     6841 caagaatata ttgcaaatag agtatctaaa gaattaaaag acggagccgt tgtaaacctt
     6901 ggaataggtc taccaaccaa agtagcaaat tatattccgg ataatgtaaa cgttatctta
     6961 caatctgaaa atggcttttt aggtttaggt tcagccgaag atggaaattc aagtgatgaa
     7021 actattgtaa atgcaggtgg tcaaccagtt actatacttc ctggaggatg tttctttgat
     7081 agtgctactt cttttggaat aatcagagga ggtcatgttg atataactgt tcttggcgca
     7141 cttcaggttg acaaatatgg caatatagca aactatatga ttccaggtaa gatggttcca
     7201 ggtatgggtg gagctatgga cctagtaact ggagctaaaa aagttattgt agcaatggaa
     7261 catacttcaa aaggttctgc aaaaatatta aataattgta ctcttccact tactgcaaca
     7321 aatgctgtag atttgatagt tactgaaatg ggagttatgg aagtaacatc agatggaatt
     7381 ttacttaaag aaataaatcc agctttcaca ttagatgatg ttatttctgc tactgaagct
     7441 cctttaatat tgtcagattc attaaatgga aaaatatctg ttgtttaaaa taattaaaac
     7501 tagaaaataa aaatctctta gacgtattac atataaattt gtattgctta aaatattaat
     7561 ataaaaataa aataaaattg gaggaaatga aaatggttaa agataaagtt gtattcgtaa
     7621 caggagctgc aagtggaata ggtaaacaaa tagctgaatc gttcttaaaa aatggtgcta
     7681 aagtaatgtt ctctgatata aatcaagaag ctttaaataa taccataaca gagttacaaa
     7741 aaaaaggtta tgattgcatg agtgtaaagt gtgatgtaac taaggaagaa gaaattaacc
     7801 acgctataga caaaactgtt gaaaagtatg gcagattaga tatattaata aacaatgctg
     7861 gacttcaaca tgtttctatg atagaagatt tcccaactga taaatttgaa tttatgataa
     7921 aaataatgct gacagcacct tttatagcta ctaaaaaagc atttcctata atgaaaaaac
     7981 aaggctttgg tcgtataata aatatggcct caatcaatgg tgtaatagga tttgctggaa
     8041 aggctgctta taactcagca aaacatggac ttattggact aacaaaagtt gctgctcttg
     8101 aagctgccga ttctggtata acagttaatg ctttatgccc tggatatgta gatactccac
     8161 ttgtcagagg tcagttcaat gacctttcaa aaactcgtaa tataccattg gaaaatgtct
     8221 tagaggaagt tttataccca cttgtaccac aaaaacgcct attagatgtt caagaaattg
     8281 ccgactatgc tatgttctta gcaagtgata atgctaaggg tattacagga caagcttgct
     8341 tactagatgg aggatatact gcacaatagt tattatattt agggcttgaa gaaagtattc
     8401 ttcaggtcct tctactaagg agggatattt atgagtatta tcgcgccaat tggtataatt
     8461 attggtatca tagctattat atatttttca gttaaagaaa ttcatataac tatagctgct
     8521 ccaatagcaa ctttaatagt tgttatttta aataaaatgg atgttgtaac gtcaatgcta
     8581 ggtgctgaca aaaacaatta tatgggtgca cttggaaact atataatgag ttattttgca
     8641 atattcttat taggctcaat acttgctaaa tttatggaag aaagtggagc tactgtatca
     8701 atagctgatt ttattttaaa taaatttggc tctaatcatc cttatagagt tttagttgct
     8761 atatttatag taagttttat attaacgtat ggtggtataa gcttatttgt agttatgttt
     8821 gcggtcattc cacttgcaag aactctattt aaaaaacttg atatttcttg gaaccttatt
     8881 cagataccac tttggcttgg tattgcaaca attactatga ctataattcc tggaacacca
     8941 gccattcaaa atgttatacc tattcaatat ctaaatacgt ctcttactgc agctactata
     9001 ccaagtattg taggtagtat aggttgtgct acatttggac ttgtctatat gaaatatgct
     9061 ctaaacaaaa gtattagaaa aggtgaaact tatgcaactt acacttcaga attagaagaa
     9121 gaatctttag atagagaatt accaggattt tttgcaagta tttttcctct attagcactc
     9181 gtaattatag ctataactgg aagtactttt ggttcagaat ttatgaaaaa aaatgtaatt
     9241 tacatagctt taatagttgc aattctttta tctgcttttt tattccataa atttctatca
     9301 tctaagatac agacattgag cataggtgct agtggttcta taggtcctat atttgctaca
     9361 tcttctgcag ttgcatttgg agcagtaata atggctgcac ctggttttga tgtatttagc
     9421 aaacttataa tgtcaatacc aggtagtcca cttataagtc ttactgtttt gacttcaaca
     9481 atgtcagcaa taacagggtc ctcttctggt gcattaggaa tagtaatgcc aaactttgca
     9541 gattattatt taagtactgg tctaaatcca gaattaattc accgtgttgc tacaatagct
     9601 tcaaatatac taactatagt tccacaaagt ggtgtttttc ttacattctt aagcttatct
     9661 aagttaacac ataaaactgg atttaaagaa actttcattg tagttgcagt tggttcacta
     9721 atagcagaaa ttattgtaat tacattagga ttactaatgt attaatataa aacaagttaa
     9781 aattcataat atgaaaggtg gtgtctcaaa gtgaactttt tacttaatga gacactcttt
     9841 ttatatgaaa taacatatgc ctatcattta aacaataaaa aaggccttat ctctattttg
     9901 agacagaccc tttttatttc ttaaagattt aaataattat aatttgttgc taatacgaaa
     9961 gcatctactg aataaattta accaaataaa aaaaaattta tcataactat aaatttacgt
    10021 tatggaatta ttataaaaat attattttct ctaactaagt aattccatac tatacaggct
    10081 tttaatacaa attgtcaaac acactgaaat atacctattt attccatata tatctttttt
    10141 acatatcttt acagtaaaaa aagtcttaat cttatgttag tatagattca cgggtaaccc
    10201 cctacactaa aggttacaaa tcagtaacat ttttagaatt tttagattaa gaggtgttta
    10261 atgatgagaa gaaatatacc aacaaaatta aaaactatat tagctttagg agtgttaact
    10321 ttagcaacag cttcaagtgc tgttactgca agtgcttcat cacttgaaaa taatgtaaat
    10381 ataagtaaca aaagtttagt atatagtaat actaaataca agttttctgc aaaaccaaat
    10441 tgttctgtaa aaccagaact taagcctgat aaagataact cttgtaagga taagaatcat
    10501 aatgacaaga attgcaacaa cactaataaa cctgaggaca acaataattc agactctact
    10561 aataagcctg ataacaataa acctgagtct aataaacctg aagacaacaa taattcaggc
    10621 tctactaata aacctaataa taataaacct gagtctaata aacctgaaga caacaataat
    10681 tcaggctcta ctgataaacc tgataacaat aaacctgagt ctaataaacc tgaagacaac
    10741 aataacaata attcagactc tactaacaaa cctgatgata ataacaactc aggctctaca
    10801 agtgaaagtt tttcagctta ccaaaaagaa gttgttgact tagtaaatat agaaagagct
    10861 aaagctggat taaatcctct tactcttgat tcttctatat caaatgttgc tacaaaaaaa
    10921 tctcaagata tgattgataa caactatttt tcacacaatt ctccaactta tggttctcca
    10981 tttgacatgt tgaaaaaatt tggaataagc tataagacag caggtgaaaa tatagctatg
    11041 ggtcaaaaaa ctcctaaaga agttgtaaac gcatggatga attctgaagg tcacagaaaa
    11101 aatataatga atccaaattt cagtaaaata ggtgttggag tagcacaaaa aagtggtggt
    11161 tcaatttatt ggacacaaat ctttgtagga taaaatactc tttttccata catatcaaaa
    11221 gagtatctct aagtgataaa aaacacaaat gagatactct tttgtatcta ttttaaaatt
    11281 atcaaatcca aatatacata ctataaatat tatttgttct cttaatttta gtgtgtagaa
    11341 caatatataa aaagtattgg caagatgaaa atggaaaact taaaaaagat atttaatagg
    11401 taaaaacaaa atcttaatat cttcataaaa aaaggctgtc tcaaaataga gataaggcct
    11461 ttttcattgt tgaaatgatt aaaatatatt tgatttcata caaaaagagt gcctcatgaa
    11521 ctaaaaagct cactttgaga cactctcttt tatcaattta tataagcatt ataatacttt
    11581 aatattattc agctaatttt ttgtatcctt catatctttc tttagcatca gcttcagctt
    11641 tagcaaataa tccatcagct tcttctggga attgtttagc tatagcagaa tatcttactt
    11701 gtgcaagtat gaaatctttg aagcttgcag ttggttcttt tgaatctaaa gtgaatgggt
    11761 ttttaccttc agcttttact tctggattga atctgtataa atgccagtat ccgcaagcaa
    11821 cagcttgtgc ttcgttagct acagttcttc ccataccttc ttttaatcca tggtttatac
    11881 atggagcata agctattatt agagatggcc catcatgttt ttcagcttct ataacggctt
    11941 tgataaattg gtttttatca gcacccatag caacttgagc tacatatacg tttccatatg
    12001 tcatagccat cattcctaaa tctttctttc tagatttttt acctgaagca gcaaacttag
    12061 ccatagcagc agctggagta gctttagaag cttgacctcc tgtatttgaa tatacttctg
    12121 tatcaaatac aagtacgttt acatcttcac cagatgcaag aacatggtct aatccaccgt
    12181 aaccgatatc atatgcccaa ccgtctccac ctagtatcca ttgagatctc ttaactagat
    12241 aatcttttct atcttttata gcttttacta actctttagc tttttcatct gtacaatcac
    12301 aagctggttt ttctaataat tcaacaacct tagcacttgc tactttagaa gcttctccat
    12361 catttctaga atctaaccac tctgtaaata ctgctttagc atcttcacag atacccatag
    12421 aaactaactc tgtcatagca tctactattt tatttcttat ttgcttaaca gctgtgtaca
    12481 taccaaatcc atattcagca ttatcctcga ataaagagtt tgcccaagat ggacctttac
    12541 cttcatggtt acaagtataa ggaattgatg gtgcagaagc tccccatata gaagaacatc
    12601 cagtagcatt agctatcatc attctatctc catataattg tgtaactact ttaatgtatg
    12661 cagtttctcc acatccagca catgctcctg aaaactccat taatggttgt ctaaattgac
    12721 ttcctttaac agtgtttaca ggcataacat caccttttgg agctacctca tcaggattta
    12781 ctgcaaatgc ccaattatct aactctgtat caagttgagt atctattggc ttcataacta
    12841 aagctttttc tttagctgga catatgtcag cacagtttcc acatcctgta cagtcaagtg
    12901 gactaagttg cattctatat tttaatcctt ctaatccttt acctaatgct tttttagctt
    12961 caaatccttc tggagcatta gctaattctt cttcagtaac taatactggt cttatacatg
    13021 aatgaggaca tataaaagaa cattggttac attgaataca gttatctatt atccattcag
    13081 gaacatcaac agctatacca cgtttttcat aagctgcagt accacaaggg aatgttccat
    13141 cttctatacc attgaatgta cttactggta agttgtttcc ttcttgtgca gtcattggtc
    13201 ttagtatatt ttttataaat tctggttctt taacttctcc tttatctgca tcaacagcat
    13261 tttcccaaga agctggaact tcaactttaa ctaaagcatt tattcctgca tcaacagcag
    13321 catagttcat gttaactatt ttttcacctt ttttaccata agctttaact atagaatctt
    13381 ttaagtattt aacagcatct tcttctggta ttatttcagc taatttaaag aatgcagatt
    13441 gcattatcat atttattctg tttccaagac ctatttcttg tcctagttta acagcgttaa
    13501 ctgtatagaa ttttatatca tttttagcta tatattgctt catatgagct ggtaaatgtt
    13561 cttcaagtcc tgcttggtcc catatagtgt taagtacaaa tgtaccacct tttttaagac
    13621 cttttaataa atcatattga taaacatatg attgtttatg acaggcaata taatcagctt
    13681 catctattaa ataagtagct cttattggag tatcaccaaa tcttaagtga gacatagtta
    13741 taccaccaga ttttttagag tcataatcaa agtaagcttg agcatatttt tcagtatggt
    13801 caccaattat tttgatagct tgtttattag ctccaacagt accgtcagaa cctaatcccc
    13861 agaacttaca tcttatagtt cctttagaag ctatttttat tggctcagat ggagttaaag
    13921 aagtattagt tacatcatca actataccta ctgtaaatcc atttttaggt tgttctgaaa
    13981 ctaagttatc aaaaacagtt tttatatctg aaggagtagt atcttttgaa cctaatccgt
    14041 atcttccacc tattatcata ggagcatttt cttttccata gaatacatca cgtacatcta
    14101 agtataatgg ttcaccagtt gaacctggct ctttagttct atcaagtaca catattcttt
    14161 caacagtaga tggcatagca tctaagaaat gtttcattga gaatggtcta tataaatgaa
    14221 ctttaactaa accatatttt tctcccttag catttaagta atctatagtt tcttctattg
    14281 tttctgttac tgaacccata gctattaata cgtatttagc atcttctgct ccatagtaat
    14341 caaataaact atgttttcta cctgttaaat tactcatttt ttccatgtat ttttcaacta
    14401 tacctactat attttgatag tatttattag aagcttctct agtttggaaa tatatatctg
    14461 ggttttgagc agtaccacga gcaactggat gatttggaga taaagcatta tctctaaatg
    14521 cttgaactgc ttcaaagttt aataaacttg cataatcttc attttctagt aattcaactt
    14581 tttggatttc atgtgaagtt ctgaatccat caaagaaatg tataaatggt aatctacctt
    14641 ctattgcagc taaatgtgca acaggtgcta tatcagctac ttcttgaact gaaccagaag
    14701 ctaataatac acatccagtt tgtctagcag ccataacgtc ttggtgatcc ccaaatattg
    14761 ataacgcttg agatgctaaa gcacgagcac ttacatggaa tactcctggt aataactctc
    14821 ctgcaacttt atacatgtta ggtatcatta ataataaacc ttgagatgct gtaaaagtag
    14881 aagttaaagc tcctccttgt aaagaaccgt ggaatgttcc tgatgcacct gcttctgact
    14941 gcatttcaac aacattaact gtttgtccaa atatattttt tcttccttgt gatgcccact
    15001 catcaactac ttcagccata gttgaagatg gtgtgattgg atatatagct gctacatctg
    15061 taaacgcata ggcaacatga gctgcagctg tatttccatc aagtgttttc ataaacttag
    15121 ccataatatg tatcctcctt gatagctaca attgtacttg tttataacaa gtctattttt
    15181 ttatatttac atataattta cacaacaaaa ctataaacac acatatagtc gcgcaaatac
    15241 tctatcttct aatataatac tacagattag ataaaattcc tttgaaaatt gtaaattaat
    15301 tacatattta agtagatttt ttttaaaatt aaatatgtta agtttttttc ataattttgt
    15361 atacaatata taataaatta agttagattt ttcaaacttt tttatctatt tgttcatatt
    15421 agtataaaaa gtaaaatgct tatccttatt acatgtaaat ttttatatat ataattttac
    15481 catattacat catatttttg taagttttta ttacattttt tataataccc ctttatttta
    15541 taaattaatc taatcgatta aatttatcct atagaaattt attacattta aaaatatgct
    15601 agcaaataaa atatctacta gcataaagtc tatttataat attaatcaac tattaattct
    15661 actaaatctc catttttaac gcctgctgca tttccctctt ccatatcaac atgcatttct
    15721 agattaaagc tgtcactagc tcttactaat acattttcaa atactaatgc tcttggtcca
    15781 gatgttttaa cttttactat ttgcttatca gttacaccaa atttagcagc atcttcattg
    15841 ctcatatgta tatgtctaga agcaactata actccttctt tcatttcaac ttctccagca
    15901 ggtcctacta atttaacacc tggagttcca gctatatcac cagattcttt tattggtgct
    15961 tttactccta atgggaaacc atctgctaaa gatatttcaa cttgagtatg agctctagct
    16021 ggtcctagta ctctaactcc ttttaaagtt ccttttggtc ctactaaatc cactttttct
    16081 tcacaggcat attgccctgg ttgagataat ggtttaaatt tagttaactc atgacctgcc
    16141 ccaaataata cgtctatatc agcttgactc aaatgaacat gtttattaga taatgctatt
    16201 ggtaatttca ttgaaattcc ctccttttaa ttatttaaat tattgcaata caattataca
    16261 taatattacc tacaaaatca aattatattg aatcaatata tatctttaaa tttttatata
    16321 ttatatcttt aaattcttga ttatctatat aagatacatc atctgtattg tttaaatata
    16381 tattgtgtaa aagtttagta tttatactct taaagaaaaa atccatcaca atctgtccac
    16441 ctttaaactg tgaatcatat gatttactcc cccccactgc aatatacatt cctatccgtt
    16501 tcttacttct atcaattgaa ggtttattta atacatattt acttgcatat atagcttgag
    16561 ttctatcaac aacagtcttt aatttagctg atattgaatc aaaatgtaca ggacttatta
    16621 ctatagttcc ttttgaatca tcaaacattt tatataatgg cttcatatca tcattaaact
    16681 tgcaataccc tgttttttca caaaatccac atgctgtgca atattcaata tccatattgt
    16741 agatattaaa tattttacaa cttaatccac actcttctag catagctttt acttcatttg
    16801 ctataaaact gcaattttta ttaattcttg gacttccatt tattattata atctctggac
    16861 ttttaagtcc ttttttatcg tttgaatcca taatcaatct acctatcctt taacataact
    16921 attaaaatat catcatcata attatctttt gatgagaagt tctttaaatc caattttaga
    16981 ttttctacta ttaactgttg atttaatcta aaattttctt ttagaaagtt ttctaatcgg
    17041 tttataccat actcttcttt tgatgaattt tttatctcta aaattccatc agtgtacata
    17101 cataccattg cataatcttc cattgaaaga gtattatttt cataagtagc atcttccatt
    17161 attccaatag gtatgccctt tttacaattt aaattatttt ctattgtgcc atctttcttt
    17221 acaactacag gactatagtg acctgcatta gacacagtaa tcatattttc tttagtatct
    17281 ataataccta tcaaacaagt tgtaaatact cccatcttgt caaattcatc atataacatc
    17341 ctatttaaat ttgtcattat ttctcttggt gtattgtatt gattgcataa tactttaaaa
    17401 gcacctttta tcattgcaac aacataattt gataccattc catgtcccat tacatcagca
    17461 acaatataaa ctatatgttc gtcatccact tttgtagcat aataaaaatc tccacctact
    17521 acccttgctg gtttatggta aaaataaagt tctttctcat cattacaatc cattttacct
    17581 ttatccataa taagctgttg ttgtttattt aatatgttca actcgttttc aagaactttg
    17641 tgttttactt ccttttcatt atgttcatat aattgcatac caacagaaac ttgtttggac
    17701 aatatactaa gaatatttaa atcatcacta gtatagtttt tgctatttgc acaaactata
    17761 catcctatag tatcattttt atcctgaagt ttgtaatata tataactttc caaatttatt
    17821 cccttttttg agcatggttt taaattattt agataccccc ccaatgactc tttctttaaa
    17881 aacatatcaa tcataggata taaatttgtt ttcttttttt gctcaacatt ataacaacta
    17941 actatagcat ccttattatg atgactattt ataattatta aagcttcttt actattagta
    18001 atattacacg cttgtttact taaattttcc aaaaagccat caatactctt attaaggtat
    18061 agttttttag tagcttcatt tatggcactt attgagcctc ttagtttatc aattaaaatt
    18121 tgtacattat tatttttatt agttatttct attgataaac ttaagagtga tgcaacagat
    18181 gatataaaat ctatatcttg ttctgttata taatcatcct cttttaaaaa acaagtcata
    18241 aatccaacaa ctacgttatt tattataaaa ggaaaaacta ttctcccaat ataaccttca
    18301 gcttttgcta aatctcgttc accttctgct ctagaatctt caaatacatt ttccacatat
    18361 attatctttt tttcatttac agcctcatgt atatactctg gatatgtgtc aaaatcaatt
    18421 tttgcacctt taagactatt tattggaaaa atttgaggta catattctaa ggtttgcgaa
    18481 catactaagt aggcatattt agaatcattt ttataaaata gattcacaca tgcctttgta
    18541 gggtgaacaa cttctaacat tttttctatt atgtcatctt ttatattaaa aaaatctgta
    18601 gattcagtca ccatagcgga tatttccact aaattcttca ttttataact gccattagtc
    18661 atactcaatt tctcccccta tatattaaac tatttattag tattttaaca tacattcttt
    18721 atagtaaaaa caaaaacaac gacaaaacta gcaactaata tccagttaaa tcctgtcaat
    18781 aatcctataa gaagtaatgt aattaatgca tttagacctg ttctcccttt ttcatccata
    18841 aaagttattt tagagatgtc gatattattt ttcacattat ttatatgctc tttcacttgt
    18901 tcttccatat ttcttttata tagtatataa actacaccaa ctaaaaacac tcctatacct
    18961 aaaaccatgt ttaaattaaa agctaccata agcaatattg aaccaaaagc taactttaaa
    19021 agcttaaaaa atacactatc tatctttaga gttatatttc tgatttcttt acattcatct
    19081 cttaaagaat atccacttga atctaagtta ttaatctttg tttttacaat ttcagaataa
    19141 aaaagcttta ttatcccatt taacattttc atcactccta aatattttac atatatttgt
    19201 aagttttaca attataatat tttttatact tggtaataat aaaaaataac aaatatttta
    19261 ttatttagta tttattgtaa ataagttatt gaagcttgat tagttaagta tagattttta
    19321 ataaatattt ttataattta gaaggaagtg gttttgtgca aatagaacaa ctcgatttag
    19381 aaacgagaaa taaaatatac tgctatacta aaaaaattct tagaaaatat caaaaaggca
    19441 taacatctgg aaaattaaca gcagataaat ttgcagataa tatattgtct caagatttta
    19501 tcagtagtat acttaatgaa aaaatagtca atgagacaaa ctttaagata tcttatagaa
    19561 actatataga aactttaata aatattcaaa atgaaaattt atctaactta agaaaaaaat
    19621 ctactaaaac tgcaaaatgt ttcaatatct ctcaaataac ccaattaaaa aacttactaa
    19681 gtaatactgg ttataattta ttaattccat ataaatactt aactgctaga gatatagaag
    19741 gaatagttac tcttattaat actgggtcta ttgaacttgg aaatgagaga atctacaatt
    19801 atatatcaaa agtataataa tttaaaccta ttataaaaag gcaatttatt taataaaaaa
    19861 tatttttaat attaaataaa ttgccttttt aattttggat taaatactgc tatccaagtg
    19921 ctttttctag tttagataaa tgttgtattg gataatattt tagtagctct ttaaattgtt
    19981 ctactgataa accttctgtt gttgtatata ttcttatttt ttcatctaag tcactattaa
    20041 taaatttgtt ttttaaatcc tcaaaattta cactactcat tttacatcac tccttatgta
    20101 acatattcat ttgtattatt ttatccaaat acataaaatt tattacataa aaatatatct
    20161 atttaataat ttaataaaaa aaagctatct caatttagaa attactttct atatttgaga
    20221 tagctctagc taaactaata gccaatagtt ataaataatt atttataact atctgttgct
    20281 ttttccagcc atttgttgtt cagccatttc aactaatttt ttagtcatgt atccacctac
    20341 ataaccattt tctcttgcag taaggtttcc tttatcaact tgttgataat tactcatacc
    20401 aagttcatta gctatttcta atttcatttg gtttaaagcc tcttttgctc ctggtactac
    20461 tgttctgttg ttgttattgt tacttgccat gttgattacc ttccttctgt ttaatttatt
    20521 ttgtgttgct gataatatta tgtgatttta aacattttta attcaggtaa tttttagcaa
    20581 ttaaaacctg ccaaatatcc agtagaaaaa gctatttgca aattgaatcc acctgtatat
    20641 gcatctatat ctattacttc tccagcaaaa aataaacctt ctactaattt tgattccatt
    20701 gtacttgaat ttatttcgtt tacttttaca ccaccagaag ttattatagc ttcttcaata
    20761 ggtctgtatc tctttactgt aaactttaaa ttttttaata aatggactaa gttttttctc
    20821 tgctctctag aaatttggtg aacaaccgta tttggattaa tttcacttaa gtttattatt
    20881 ataggtatta gtttttttgg aagtaaatca tctaatgctt tttcaaattt tttatttgta
    20941 tacttctgaa aatctttttg aactctttta tccaattttt cctcatctaa tgcaggtttt
    21001 aaatctaata atatagtgta attttctttc cttgtatctt tcattctaca acttgcagac
    21061 ttgattatag gtccatctaa accaaattta gtaaattcaa gttctccaaa atcactataa
    21121 actttctttt gtttgctatt aaacaccctt atttcaacat ttctcaatga taatttttct
    21181 aaatcttttg taaaactttc ttgtacttct ataccaatta aagatggttt tgtatctata
    21241 attgtgtgcc cctgtgaaat tgcaaattta tatccatcac cagtagaacc agtaagtgga
    21301 taacttaatc caccagttgc tactacaact gaatcacact taatttcttt tttatcgttt
    21361 aaaattactt tttcaatttt attattttta gatattattt tttctacttt cgaatttaat
    21421 aatatattta ctttcttact tttaagttgt ctttcaagag catttacaat atcaaatgct
    21481 ttatcactct ctggaaaaac cctttttcct ctttctgttt tagtctttac tccaagatta
    21541 ttaaacatac ttattacatc atcatttgta aaagtataaa aagcactata aagaaatttt
    21601 ccatttgtag gtacattttc tattaattcc tctatttcac aagcgttagt aatattacat
    21661 ctaccttttc ctgttattgc aagttttttt cctaatttat gatttttctc aattaatgtt
    21721 acatcatagc ctttctcaca tgcagttgat gcggctatca tccctgctgg tccaccacct
    21781 attattacta ccttcttcaa ataatcactc ttttctaccc ttaatttttt taatttaaac
    21841 tattgactct ataccttaaa atcaatttaa ttttaaaagt ttaaataatg ctggagctcc
    21901 tgctattcca taaaaaacaa ctactgtatt cttaataaaa ttcataaaaa ttatactcat
    21961 agtagagtca cttatattta aagtgactat taacattgaa ataaacaact taatgccaat
    22021 atataacatt cctattgtta ctatcccaac caaaaaccta catattcttg aaaaaattat
    22081 atttttactc cccttatttt tattgctaaa atttattttt ttgttattat tatctgtatt
    22141 aaatttaaca aatctatcct caaccatata tccaaataca aatcctacta ttataccaaa
    22201 tttttcaaaa tattcagggc tatttagaaa tatagccact attataaatg gtataagtaa
    22261 aactacaagt aaaatataat ttttattatc atcaatatag tcaaatattt ttacaaatac
    22321 aactgtaaaa aatattccta atatccaacc cgctatcaca tctattggcc aatgaacagc
    22381 taaatacagc ctagacaatc ctactcctaa aaccataact gcacctatta aatgaagata
    22441 tctcttttta aatatagtca taatactaac ccaaaatgtt gttgcagttt gagtatgagc
    22501 acttggaaaa gaataaccac cagcagtaga aactctcaat gattcaagac cttttattcc
    22561 tattggtctg ggagctttta caaactcttt gatgcctaaa tttacaacaa aatttccaat
    22621 tatagcaaac agtattttct gtccacattt tttatttata caccagtata taattgttgt
    22681 aattaatatt aataacggtg cttctgtgct tattgtaaag acaagaaata taaagttcaa
    22741 aattggattt cttaaatttt ggaaaaataa taatatattt aactgaatat ccatatagat
    22801 gtctccttta ctaaaatttt atataattaa ctaaaaagca ctaactccct tagaaattag
    22861 tgcttttgat tcacatttaa atctattcta catcctcaac tatacctata taaggtaaat
    22921 ttctatactt ttcagcatag tctattccat aaccaacaat aaatttgtct tctataacaa
    22981 atccaacata gtctacaggt atattagctt ttcttctctg aggtttatca agtagagtac
    23041 atagttttaa agattttgga tttctagttt ttaaagctgc aactagatta cttaatgtta
    23101 aaccagaatc tattatatcc tctacaatca acacattctt tccttcaata tctacatcta
    23161 aatcttttaa tattttaact gttccagaag actctgttga gtttccataa cttgtaacac
    23221 tcataaaatc tatatttaca tccaaatcta tacatcttat taaatctgaa acaaatacac
    23281 tagctccttt aagtatacct accactagta aatcttcgcc tttaaagtct tcttctatct
    23341 tttttcctaa ttcataaact ttttctttta tttgttcttc tgtcaacatt tttcctgtaa
    23401 ctttgtacat tttgtatcct cccgctttcc ttctattaac ttatatatta tagcatacca
    23461 aaatatcaat taaaatcttt ttcatcattt ttaaacctaa attaacagct tatccatact
    23521 tttttgcttt ttacattaaa aatttggaat aacgattcct ttgtattata atctatatgt
    23581 acatatatta atcagttatt tttatcgatt atataatttt atttttggag gtacttttat
    23641 gagcacaaac catggagcta atttatatag tttatctagt aagtatggct tttcaaagga
    23701 agaatttatg gattttagct caaatataaa tccttttggt acatcaagtt tagccaaaca
    23761 atacattgta aacaatatag atatggtatc tatgtatcct gaccctgatt acatagactt
    23821 aaaaacttct atatccaatt actgcaaatg ttctatagat aatatagtac ttggcagtgg
    23881 agctacagaa ctaatttcat catttataca tacaattaac cctaaacagg ctcttttact
    23941 ctctccagcc tattcagagt atgaaaaaga gttatctaaa attaattgtt ctatagaaaa
    24001 atactttgca aaagaagaag ataattttca tataaattta gaaaatctta taaaaactat
    24061 caatgctaaa gattatgatt tggtagtaat ctgtaatcct agtaatccaa ctggatttgc
    24121 atttactaaa gtagaagtga gagaaatttt aaaaaataca gactcatttt taatgattga
    24181 tgagacttat gtagagttta ctgatacaga tacatactct tgtactcaat tagttgatga
    24241 ttattctaat ttattcgtta taagaggtac atcaaaattt ttttcaacgc ctggaataag
    24301 gcttggatat ggtcttatat ctaacactaa tgtcaaaaat gaaataaata aaaatctaga
    24361 tttatggaat ataaacataa tagcttctaa aatgggtgaa atcatgttta gtgatttaga
    24421 ttttatatca aatactattt ccttaatgaa cactgaaaga gattacctgc ttaaagagct
    24481 taagaatata aaaagcttag atatatacaa tactaaaggt aatttcatat tgtgtaaaat
    24541 caagacaaag gaattgactg ctaaatctct tcgagagcaa ctgcttccac aaaaaataat
    24601 aataagagat tgttgttcat ttgaaggtct agatgagtat ttctttagag tatgtatatt
    24661 aaaacctaat gaaaataaat tattaatatc atctcttaaa gcaattttta aataaaaaaa
    24721 tcactttatt ttataatttt ttataccata aaaaatgagc tatctctatt tgagataact
    24781 catttttgat tattaaaaaa ctaagcactt tgctcttctt tatttccttt tttactcatt
    24841 ccatcattta ttttatctac tactactgct attgcattat ctcctgatac attacatgct
    24901 gtaccaaaac tgtcttgagt taagtataaa gctatcatta aacttgcaag cccaccatct
    24961 gatggtattc caaccattgg taggaaagga agtgcactca ttatagcccc acctggtgct
    25021 cctggtgctg caaccattgc tatacctaac attgcaatat aagggaataa tacacctatt
    25081 ccatgtggca taccattcat cattaaaact gcagttgtaa atcctgttat tgatatcata
    25141 ctacctgata aatgtattgt tgcacaaaga ggtacaacaa attctcttat ttgcttactt
    25201 actccatttt tttctgcaca accaacatta actggtatag ttgctgctga agattgagtt
    25261 cctatagctg ttaaatatcc aggtacttga ttttttaaca ttcttactgg attttttcct
    25321 gaaaatacac ctgctgctgt gaattgacat gccatatata caaaatgtaa aggtattact
    25381 actaagtata ctttccagaa tacccctaat attgtccata cttcccctgc tatagttata
    25441 tttgcaaaag ttcctgctat gtataaaggt aataaaggta taatcactgt tgacaacgtt
    25501 ttcgttacga ttccttgaaa ttcttggaag aaattaaata aagtctctcc ttttccatga
    25561 tttcttaaag ctgatattcc aagtcccatt acaaatgcaa atacgattgc agctgttaca
    25621 tctaccatag gctctaatgg aattgtgaat attggagcta acattcctgc ctctgggtct
    25681 ccaatttgac ttgcaacact tgcatcaata aaatttggga agattaatgt agatactgca
    25741 aatgataata atcctgctat taaggtagaa ccatatgcta ttcccgtagt tatccccaat
    25801 aactttcctg cacctgttgc taaatcagct atacctgctg ttacaaaacc tataattata
    25861 aatggtataa caaattttag gaatgctgag aataaagtac taactgttac taatatttgt
    25921 actattattt ctggtgcata acttccgatt aaaataccga ctatgatacc gatgattagt
    25981 ttgggcacta aacctatttt tttcttcata atatttaccc tccataactt ttttaaatta
    26041 agcattcttg cacattgaat acttagttaa atattggata tccacttatt atgataatag
    26101 agttttacct ctccgtcaac aatttaacca ttttttgtta ataaaaaaaa gaataacata
    26161 tataaattgt tattcttctt catcttttat agaaaattct acattttcaa ttatatttga
    26221 atgtttatct ttttttgcga taactctata cttattaatt tcttcattca ctatacctat
    26281 actccaaatt aaaactatag catcatctat aaaaccaaat gcccctgcaa tcatctctgg
    26341 aattatatca accccagata caaagtagga tatagtaaaa attaatacag aaattacctt
    26401 tattttatca actatattga ttcttttatc tgtcataaaa tcaggtagtt taagtaaatc
    26461 aaatacaaaa accaaaccaa atttagcatt tttaaatctg accaaaattt tttttaaaat
    26521 atctaaaact atattaatga ttatttttaa aaactccata tttatcacct cttataatta
    26581 taggttattc tacattataa ccgatataat taatttgatg aacatattag atataaattt
    26641 tatcaattag tttatattta aattataata attcaattcc tgcactacta caattttgaa
    26701 tcatatcctg tggccatact ccaacttgta cttctcctat atgagctttt tgtaagaaat
    26761 acatacatat tcttgactga ccaattcctc caccaattgt atacggaagt tcgccattta
    26821 aaagcatctt atgatagtca aactcttttc tctcttcaca tccagcaagt ttcaattgtc
    26881 tatcaagaga ttcttcatca actctaattc ccattgaaga taattctaat gctgaatcta
    26941 aaacaggatt gtaaaataat atatccccat tcaattccca atcatcataa tcaggacttc
    27001 ttccatcatg tttttctcct gatattaatg tttttcctat ttgagttata aatactgctt
    27061 tcttctcttt tacaatttta tcttctcttt cctttggtga taattctgga tacatatctt
    27121 ctaactcttg tgatgttata aaagttattt cttctggtaa tatttctttt ataccttcat
    27181 acatactaca tacaaaaatt tcagtatctt taaatactcc atacaatctt tttacaacat
    27241 cttttagagt cttttcattt ctactacttt tatctataac caattcccaa tcccattggt
    27301 ctacataaag agaatgtata ttgtctaatt cttcattttt tcttattgca ttcatatctg
    27361 tatataaacc actaccaact tcaaacccat attttttaag ggctaatctt ttccattttg
    27421 caagtgattg aacaatttct gcatttttat tcataaatgg tatatcaaag cttacagcct
    27481 tttctccatt taaattatca tttgcacctg tttctggcaa tacaaataac ggagaagaaa
    27541 ctcttataag atttaattca ttacttagtc tcatttcaaa aaaatctttt aattttttta
    27601 tagctatttg tgtatcaatt acgttcaaac tacttttata atcctttggt attattgtgc
    27661 tcatatcatt cactccctat atttatatat ttttccatta aaaaaaccct tcatccctat
    27721 ataaaaggga cgaaaggttg cttttccgcg gtaccaccct gattagtttg aaataaattc
    27781 aaacccagct cacaatgtac agatattact cgatacaccc caatatgata acggtttggt
    27841 tccgactaag cctactcttt taaaatttcg gttagcaact ccaggatgtt cttcactata
    27901 gacttcatat tggtctcaca ccatcaccaa ctcgctttaa ttacattcta taactactct
    27961 tcctttcaaa gtctttaaga gtttaattca ataaaattta gctctcttat gttttctatt
    28021 tattcataat agtatgataa gtgattagtt aaaatttgtc aagtttatta tttttttatt
    28081 tttaaacact ttataaattt ttacctatac tttataaatt ttcaaatata gtctttaatc
    28141 tgtccataca ttcttttaat aaagactgtg gacaagctac atttattctt tcaaatccta
    28201 ttccttcttt tccaaatata taaccttcat caaataatac attagctttt ttaaacatta
    28261 aatcttcaag ttctacttca tttaatccat aagcagtaaa atctaaccat gctagatatg
    28321 ttccttctgg ataaacaagt tttacttttg gtaggttttc ttttaagtat tcatcaataa
    28381 attgtatatt attatctaag taatcattta attcattaag ccagtcttca ctttcattat
    28441 atgctgctat tgtagctaca atagcaaagg gatttggtga agttgcaact ccaacagctg
    28501 taacctcttc ttgatatttc ttttttagtt catcattatt cactattata ttagacaact
    28561 gcattcctgc cagattaaat gttttacttg gagctataca tgtaactatt ttatccttgt
    28621 actctgggca taatgactgt aaaggagtat gtttaaatcc ttttctaatt aaatcagaat
    28681 gtatctcatc agctattatc cataggtcat attttttaca tatttctaca acctttttta
    28741 attcatcttc tctccaaact cttccaacag ggttgtgagg actacaaagt attagtactt
    28801 tattgttgct acacttagct ttttcttcta aatcatcata atccatccta taagtaccat
    28861 tctcatatat cagaggattg tttacaacgt ccctattatt gctctttatc ttagcttcaa
    28921 atgggtaata cactggtttt tggactatta caccttcatt agaattagtt aatattctta
    28981 ctaaaatagc aacagcaggt acaacaccag gactaaaaat aatatctttt ctacttattt
    29041 cccagttaaa tctcctttta taccaatcac aaactgcatt aaagtattta tcactatcat
    29101 ttgaactata tccaaatatt ttatgttcaa cttttttacg taatgcttct attattggtt
    29161 ctgcacattc aaaatccata tcagcaatcc aaaaaggcaa accatctttt tgtgcttttg
    29221 ttgaacaatt agttctaaaa tcccatttta cacaatctgt tcctactcta tctattactc
    29281 tgtcaaaatt atacttactc attttttccc tcctaagaat aaaattttta taattgttaa
    29341 gtctattact agatgcactt tggtattatt ttacaattct taatattata ataatatcac
    29401 ttttttgtcc aatagattta aaatataatt acttttccat catatttttt caatattcca
    29461 aaatcagttt cattatatca aaataagatt gctcatatta attattttct aattaacata
    29521 agcaatcttt ttctataact tctataatta taattttaaa tgtagaatta ttagtttgga
    29581 tgttatccca atctcttttc aaccaatcta caccatatat ctacaccata ttctaaagct
    29641 ttcgtatcaa atgttacatt tggattatga aatcctggtg tagcatcagc tcctaatcca
    29701 atatatgtag ttttacattt tagtttttgt gtataataat ggaagtcttc tccaccagaa
    29761 tttttaaata tacctataga tgcatcagct cccaatacat cttttatagt ttcttcagcc
    29821 aagtttacaa gttcttcatc aaattctgct gctggtactc catctttgga aattagtaca
    29881 gcttctgcat ttatagaact tacaacagtt tttacagcat gtattgcttt ttcttttaat
    29941 tcttctatta tatcattact ttctgccctt atatctaaag ccataaatgc ttcatctggt
    30001 atattattat aagtttctcc cttaactgat atatttgtta cttttataga atttggtata
    30061 gctggattta ctcttattgc atttattgca ttcactgcta aacagacagc atctactgca
    30121 tttactccta aatgtggttt agaaccatga caagtgatac ctttaatcgt aaattccatt
    30181 atacagctag cacaatggta cattgcaggt atcgcctttc ccaacctaca atcttgtcca
    30241 ggtcttaaat gcatccctac catttcttct acatcatcca acaaaccaga atcaattact
    30301 cttaatgctc catataattt ttcttcacct ggttgaaaaa gtatttttaa cttacctctt
    30361 tttactaaat ttctctcttt tattaacttt gcagctgtta aaagcataga agtatgacca
    30421 tcatgaccac aagcatgtat cattttcttt tctccatcta tgataaattc caatgcatcc
    30481 atatctgctc ttatagcaaa tactggtcct tcttttttag aatctatagt tactataata
    30541 ccagttcctg caactccttt attaatattt tcaaacccca ttttttcaag ctcttttaaa
    30601 acaaactctg atgtcttata ttcttcaaat cctttttctg gtatagtgtg tagataatca
    30661 tacactttat gtacatactc aatataatct ttgttagttc ccataatcta gctcctcctt
    30721 aaaatttaaa ctttccattt atattaaatt tttattataa ttacctatac tacgaaataa
    30781 ttcattataa gcattgcaat acaaccattt aaagttgcta taacaaacat atgtggataa
    30841 tatttagttt ttaactcagc tgttcctaaa agtctcccca taaattgtat ctgcgctcct
    30901 gaaagcaata acattggcaa tagaattgca acatgtgctt gacttatttg acctgctgta
    30961 aataaacctg cgattactcc agatgctcct cccattgata taaatattgt cattatagct
    31021 gttgctgcaa cacctggaag tccaaagata ctcattacag gtgtaaatat tgtccctatt
    31081 acatccaaaa gacctgttaa gttgaacaca gaaattatag caaaaccgaa gatgacattt
    31141 ggagccattg aatttgtact tatttggaat ccatttctag ctcctccaat aaacgcatct
    31201 atcacatttc cttttttaac ttttacttct ttttttgcta cctcactcat gttaagcttc
    31261 ccccttgtca aatttattta aatataatct aagtaagttc gccccaacaa acttcataat
    31321 taatattaaa gcaagtggta taaatattgg tacatctcct ataaatggaa atagtgctgc
    31381 tccagaagca aagaaattcg taattgcaga cgcacctgaa aattgaaatg cacaaaatac
    31441 agctttttgt ttttcatcta tatacccatc atctttaagt tctttagtca tagatgcagc
    31501 tgcatctgta gactgtaaac tagctatcaa agttagtcct gcaaatccag gtaaccctaa
    31561 taatggcttt aatagtggac taagaagctt ttgagctgcc ttcattccat ctaagtggtc
    31621 tataactcta actactccaa gtgcaaacat aactgatggt attaatgtca atgcatatag
    31681 ccatccatct cgagggccag tacctccatc acctctaaag tttgcagcta atgtacctac
    31741 accatcatta attgttccca atgttccaaa agaacctaat acattgttaa aatccaatac
    31801 ttttaatggt cctggtgcat ctttaaatat tcctgaaaaa aataatgctc ccaatattaa
    31861 tgctacatac ccataccatt ttacctcaac tttttctgtt gttgattcta atttactcat
    31921 ataaattctc cctcctgttt aaatgaattt tattagtata cttgtttaat aagcaaaact
    31981 tatgccaata ccttaatgat aaagcctttg tatttatttt tttattgtaa atttattcca
    32041 gtgattaaat agcttataat tacttacttt tcaagtttaa aaatataata tttttttatt
    32101 aattatttaa aatatacatt acaatataaa aagctatttt ccttatcttg caaaaataat
    32161 ttcaaaatag gtttttatag gataaaatcc taaaaaaacc tattatttaa tcaaatatat
    32221 aaatttatac tactatttgt tgtataatat aacttgcctt atactttaaa tactttaaaa
    32281 ataaatacta ttttgttagg agaaataaaa tggataaaaa gaagttaatc cttataacat
    32341 atgataaatt gaatagtgac cactacaaag aagaattaac aaactttttt ggagacgaaa
    32401 taatcataga aacacaaaat atacttgatg gaataaaaga aaatttagag ggagatgtag
    32461 tgctttctct atcaccttta actagtaatt ttttaataaa acattttaag gaagatattg
    32521 aaattattca tggaacgaaa gcactttcaa aacttggata tgaaaaaatg atgaaactgc
    32581 ctccaggtac aaaatcgtta cttatgacaa ccaataaaac ttcagcattt gagatggcta
    32641 cttatctata taaaattggt ataaatcata tagattttgt accgacatat ccagattgtg
    32701 atgaaatata tgatttagat acagctataa caccaggtca gattagattt ataccaaaat
    32761 acataaaaaa tattgttgat ttaggttgga gaaaaatctc attagataca tatatgtcat
    32821 tattagtagt attaaaacta aaaaatgaga aatttataga aaaattatac aaattgtcca
    32881 aggagacact aagtcatgat ttcttaaata catcattaga taatatatct aaattaaaaa
    32941 ctatacttta catgaccatt gatgaaatag gtgatggtct aatatttttc aataccttta
    33001 ataaggttac ttttgtaaat aagtctttac ttaatatgtt ggaactagat gaaaaactta
    33061 taaaatcacc ttccttaatg gaatatatgc caaagagttt cttagataaa attacaaaga
    33121 acttaaatat agataatatg attatataca tagacgaaat agataaaaaa ttcatacttt
    33181 ctaaaaaacc attttatctt tataaaaata tagagggttg cttaattaca ttaaaagatg
    33241 taaacaatat agaaatatta gaacaaaaaa taagaagtga ttctgtcaaa agaggttatg
    33301 tagctaaata taaatttaat aatattattg gaaatagttc tattataaaa gattgtatta
    33361 aaaaggcaaa aaaaatggct cttacagata atcctatatt aataacaggt gaaacaggaa
    33421 caggtaaaga agcctttact cagtcaatac acaatcattc aaatagaaaa aataaacctt
    33481 ttgtagcaat aaattgtgct tcattaccaa gtgaattact tgaaagtgaa ctatttggat
    33541 atgaagatgg ttcttttact ggagcaaaaa aaggtggaaa aaaaggatta ttcgaattag
    33601 ctcatactgg cactatattt ttagatgaga taggagatat gccacatgat ttacaggtta
    33661 aacttttaag agtcttacaa gaaaaagaaa ttagaaaaat tggtggtaca agtattattc
    33721 caattgatgt gagaatatta gctgccacaa ataaagattt agagaaatta attatagaaa
    33781 ataaatttag gatggattta ttttatagga taagtatgtt cactttagat ttacctcctc
    33841 ttagaaagag attagaagat atacctcttc ttttagaatc atttttaaaa gaacttccct
    33901 ataaaaacat aaaactcgat aagagtcttt tagaagcttt aaattcatac acttggatgg
    33961 ggaatattag agaactgaga aattgtgttg aatatatggc ttacatgggt tccaattatc
    34021 ttacaataaa tgatttacct caaaacatat cttcaaaatt aaataataat catatgtcaa
    34081 gtaatatgtc catattcaat gatttaaacc aatatgacaa aaacatatgc atttctatcc
    34141 taaaatcatt gcacatgaaa ccaatgggga ggacaaagtt aatgaaattt atggaatata
    34201 atgtcacaga atacgaagta agaaatatgc tagaatattt gacacgcaat ggatacttaa
    34261 tttctagtaa gggaagaaaa ggctcatcaa taactgagaa aggcataaaa ataat
//
LOCUS       DAEHWO010000039        34207 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEHWO010000039 DAEHWO010000000
VERSION     DAEHWO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.039"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            238..759
                     /locus_tag="KNP54_002210"
     CDS             238..759
                     /locus_tag="KNP54_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0893108.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            793..1569
                     /locus_tag="KNP54_002211"
     CDS             793..1569
                     /locus_tag="KNP54_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0893109.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDKI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            1911..2864
                     /locus_tag="KNP54_002212"
     CDS             1911..2864
                     /locus_tag="KNP54_002212"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBF0893110.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            2882..3901
                     /locus_tag="KNP54_002213"
     CDS             2882..3901
                     /locus_tag="KNP54_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBF0893111.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            3932..4183
                     /locus_tag="KNP54_002214"
     CDS             3932..4183
                     /locus_tag="KNP54_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893112.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            4465..6270
                     /gene="lepA"
                     /locus_tag="KNP54_002215"
     CDS             4465..6270
                     /gene="lepA"
                     /locus_tag="KNP54_002215"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBF0893113.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            6419..7756
                     /locus_tag="KNP54_002216"
     CDS             6419..7756
                     /locus_tag="KNP54_002216"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBF0893114.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            7989..9302
                     /locus_tag="KNP54_002217"
     CDS             7989..9302
                     /locus_tag="KNP54_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBF0893115.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            9474..10649
                     /locus_tag="KNP54_002218"
     CDS             9474..10649
                     /locus_tag="KNP54_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBF0893116.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            10752..11771
                     /gene="hrcA"
                     /locus_tag="KNP54_002219"
     CDS             10752..11771
                     /gene="hrcA"
                     /locus_tag="KNP54_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBF0893117.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            11801..12421
                     /gene="grpE"
                     /locus_tag="KNP54_002220"
     CDS             11801..12421
                     /gene="grpE"
                     /locus_tag="KNP54_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBF0893118.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            12513..14360
                     /gene="dnaK"
                     /locus_tag="KNP54_002221"
     CDS             12513..14360
                     /gene="dnaK"
                     /locus_tag="KNP54_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBF0893119.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            14571..15725
                     /gene="dnaJ"
                     /locus_tag="KNP54_002222"
     CDS             14571..15725
                     /gene="dnaJ"
                     /locus_tag="KNP54_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBF0893120.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            16691..17626
                     /locus_tag="KNP54_002223"
     CDS             16691..17626
                     /locus_tag="KNP54_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBF0893121.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            17662..19035
                     /locus_tag="KNP54_002224"
     CDS             17662..19035
                     /locus_tag="KNP54_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0893122.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(19223..19990)
                     /locus_tag="KNP54_002225"
     CDS             complement(19223..19990)
                     /locus_tag="KNP54_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0893123.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDFI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(20020..21129)
                     /gene="ugpC"
                     /locus_tag="KNP54_002226"
     CDS             complement(20020..21129)
                     /gene="ugpC"
                     /locus_tag="KNP54_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBF0893124.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRNLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            21387..22124
                     /gene="cas6"
                     /locus_tag="KNP54_002227"
     CDS             21387..22124
                     /gene="cas6"
                     /locus_tag="KNP54_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBF0893125.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPINFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            22129..23604
                     /locus_tag="KNP54_002228"
     CDS             22129..23604
                     /locus_tag="KNP54_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893126.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENRLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYSFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKRMIDNGNLSNLKELLLDNISVLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            23624..24637
                     /locus_tag="KNP54_002229"
     CDS             23624..24637
                     /locus_tag="KNP54_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HBF0893127.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVIGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            24653..25450
                     /gene="cas5"
                     /locus_tag="KNP54_002230"
     CDS             24653..25450
                     /gene="cas5"
                     /locus_tag="KNP54_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBF0893128.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYIKMGKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVKLKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            25477..27885
                     /locus_tag="KNP54_002231"
     CDS             25477..27885
                     /locus_tag="KNP54_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBF0893129.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKSTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            28326..29273
                     /gene="prmA"
                     /locus_tag="KNP54_002232"
     CDS             28326..29273
                     /gene="prmA"
                     /locus_tag="KNP54_002232"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBF0893130.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            29292..30050
                     /locus_tag="KNP54_002233"
     CDS             29292..30050
                     /locus_tag="KNP54_002233"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBF0893131.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEIILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNSVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            30052..31350
                     /gene="mtaB"
                     /locus_tag="KNP54_002234"
     CDS             30052..31350
                     /gene="mtaB"
                     /locus_tag="KNP54_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBF0893132.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            31393..31743
                     /locus_tag="KNP54_002235"
     CDS             31393..31743
                     /locus_tag="KNP54_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBF0893133.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            31906..32085
                     /locus_tag="KNP54_002236"
     CDS             31906..32085
                     /locus_tag="KNP54_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBF0893134.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            32115..32558
                     /locus_tag="KNP54_002237"
     CDS             32115..32558
                     /locus_tag="KNP54_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBF0893135.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            32669..33166
                     /locus_tag="KNP54_002238"
     CDS             32669..33166
                     /locus_tag="KNP54_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBF0893136.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            33359..33922
                     /gene="raiA"
                     /locus_tag="KNP54_002239"
     CDS             33359..33922
                     /gene="raiA"
                     /locus_tag="KNP54_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBF0893137.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
BASE COUNT        13800 a         3535 c         6087 g        10785 t
ORIGIN      
        1 ataaaaatat aaatttatat gcttaattaa gataattttt ttcattagta tgtatgatag
       61 atgcatcaaa caatataact aatatgttag aaggttatat gtaattaatg tcagtgttta
      121 tatagaatag catttgtagc atttattata gttgtaatta ctatttatat catagacttg
      181 aatagtctaa aaaaatagac tataatattt ttatagacta aagaaagggc tgataagatg
      241 gacatagcaa aactaatttt aaatcctgca aggcttcgta ttttacaata tattcgactt
      301 tatggcagtg ttcgtacatc tgatattgta aagtatttaa atgatattcc tcgtgcaaca
      361 gtttatcacc atgtaaaaat tttagaagag aacaatatga ttgaagtaat taaagaaaat
      421 cgtgtgcgtg gtactattga aaaggtttat gcactaaagg aatatacaac atctatggaa
      481 ggagagacct tcgttgcact ttctacagca ttttatgtag gtctgatgca ggaaatgaat
      541 gaatacttta gcagaaaaga gcaagaccat aaaaaggata atgtattttt ctcttcagca
      601 ttactatata tgagtgataa tgaatatgaa aatcttctta aaagtatagc tgatttattg
      661 aaaccatata tagaacaaaa acctaaatca aatctaaaac ttagaaaact ttcaattata
      721 tcttctccac ctgtagctga taatgataaa acaaaataac atgcaaccca tttttataaa
      781 aggaggttat atatgaaatt tcatgagttt ggaaataaaa acagaccaca tattatgttg
      841 attcatgggg gagggaatgc atggtggaac tatttgcgac aagcagaagt tttgtctaac
      901 aaatatcatg tgatacttcc tacattggat ggtcatggag aagaatatga aacaacatac
      961 atttctacag aggatacagc agataagttg atatcatata tagatgaaaa ttgcagtgga
     1021 catcttttcg ctttgtgtgg ggtatcactt ggtggtcaaa ttgtcatgga acttttatct
     1081 cgaaaaccta atattactaa aaaagcaatt attgatggta gtatttgcta cccaagacct
     1141 cttatggcaa ggttttgtat tgctggtatt cgattttttg gaggactttt gtttagtgag
     1201 aaggcttgtc gctttcaaat tgctatgatg ccaaaattgt tacctgaaaa tatgcaatat
     1261 ccagataaaa taaaagcgta ttatatgaca gatatgccac atgtaagaaa agaaacattc
     1321 tataatatgt atcgtactta catgatgaac tatacactta aagagaatgt taaaaaaacc
     1381 acagcacaag taatgtactg gtatggagaa aaagaaatga agtgtgtcaa aaaatctgca
     1441 aaactgtttc agtcttatgt gccctcttgt gagatttatg aagctaagag ctataatcat
     1501 gggtatttat cactttatct tccaaatgaa tggttggaaa ttgcagaacc atttttccaa
     1561 aaggaataaa ggtgttaggt gattattgta taattattgc tgttttttta tatagtaaat
     1621 aaattaggta taaatataaa aaattatttt agttaatata ttagtgaaag cttaatagga
     1681 aaattataaa tagattaaag gtagcaccta tataaatagt tgctaccttt ttctgtttgt
     1741 aaataaatga tagataagaa ggtttactga caaatcactg actaaaccca attttcttac
     1801 attgaaagcc ttaattttac ttgttttaaa taaatttaca atttcttgtt ataaaatact
     1861 aaattttgtt aacaattata attagcattt aatttatact ggaggtttat atgattagtg
     1921 taagaacaga tttagcttta gaagctagtg aaatgtgtga aaagtctcaa gaaggaagta
     1981 gtattcctgg tgtaaaaata gaaactaaag aattagaaaa ttgcattgta actaaagttg
     2041 aagtaataga caggcaaggc gcagagataa tgaataaaga tataggaaag tatataactc
     2101 tggaaagtaa tcttatgaag tttgatgatg atgagtcaag agaagaaatg ataagttatt
     2161 taaaagagga gttagtagat atatttggcc aagacaaaaa taaaaaaacc ctggtaattg
     2221 gtcttggaaa tagaaatatt acttctgatg cgttaggacc aaagagtgta tcaaaaacac
     2281 ttgtaactag acatcttttt aaaaattata ataaagacta tgatgatgat ttcactgagg
     2341 tatcagcttt aagcccagga gttatgggtg ttactggaat agaaactagt gaaatagtaa
     2401 aatcattggt tgagaaggtt aagccagata gagtagtagc aatagatgca ttggcttcaa
     2461 gaaaaatgga aagagtaaac tctactatac agatatcaac agcaggaata tcacctggtg
     2521 gaggtgttgg caatactaga aaatctctaa ctaaagaaac tttaggcgtg gatgttattg
     2581 caataggcgt tccaacggtg gttgatgcag caactcttac aatagatgtc ttagatatgg
     2641 caatagacaa tttaatagct caatcagaag aaacagaaag tttttatgaa atgttgaaaa
     2701 aacttaaaga agaagaaaaa tatcatctaa taaaagattc gttagaccca tatgacaaga
     2761 acttaatagt aacaccaaag gatatagatg atacaatcga aaatctatct ataataataa
     2821 gtgaaggctt aaataggtct ttacatccag gtagattggt ataaaataag gaggagcaat
     2881 tatgtttaaa aaatgcatta aagtagtaac cttgactttt atattagtat gcattttacc
     2941 aggaaaatca ttagctttga atcaagatga ttttttaaag tttttagtaa attcatctta
     3001 tccagaagct aaagtcgaag gaaatgatac agaaaataaa aagaataata aaaataaaga
     3061 aacaagtaag gaaaataagg aagaaagtaa agaaggaaac actaaatcta aagatgcaag
     3121 taaagttgat aataaaaaag agagtgaaaa agaatatata aaactttatg ttggtaaaga
     3181 aaatgttcca gatattgagt caaaaaattc agacacaact gaaactaaca caacatctag
     3241 ttcagattat aaggatgatt taagagtaac caaagaaaat ccaagaattt tgatatatca
     3301 tactcatgga tgtgagactt attcaaattc acctgatgga aattatcatt caagagataa
     3361 gaaaaattca gtaatggaag taggaagtgc attaactagt gctttagata gcaaaggatg
     3421 gggtgtagtc catactacta aataccatga ctatccatct tataataact cttatgcaag
     3481 tagcttaaaa acaatacaaa gtatattacc taaatataac tcagtggata tagcgataga
     3541 cttacataga gatgctaggg atttaactaa tccagccact aaggaaaaag accatttaaa
     3601 atatacaact atgataaatg gagagagagt atcaaagttc ttctttgttg taggaggtaa
     3661 aaatacaaat agaaaacaac ttagagcttt agcagaagat ataactgctt ttgctgagaa
     3721 aaagtatcct ggtctagtat ctccaatagt agaaaaagac tatgctagat tcaatcagtt
     3781 tgcagttaag aatcatatgt tagtagaaat agggaataac gcaacaagtg tagaagaatc
     3841 taaggctact acaaagtatt tagccgagat tttggatgaa tattttaaac aaaaaaatta
     3901 gagctttaag ttataattag gagcacgcta aatgagccga ttagaaaaaa atatagaaag
     3961 taaaagtaaa ctaagaaaat acaagtatat tatgagaatc ttatttttga ttactatgat
     4021 tatatgtaca tcagtttgtg tatttatagt ggacagtaat gcaaaaagta tgctaggaat
     4081 gaaacaatat gattttccaa gtattaaatt tgatataaca aaatttgatt ttgacatacc
     4141 aaattttgat atacatgaaa tcataaaaaa atttaataag tagtaataag tgaataaggt
     4201 ttattgatta aaataagcct tattttagtt atatattttt aatgtataaa ataaaaattc
     4261 attaactgta ttttatagga tttactttaa gtttatgata ttatataata tttagtgtta
     4321 gacttgataa tccacatata atgtggataa ttttgtttag tgccaattag tttatattca
     4381 aaaattttaa atttggtata taaagagttt ttagataatg taaaataata actataagaa
     4441 taatcaagag gagggaattt taaggtggac aataaacaaa gtagaactag aaattttagt
     4501 ataattgcac atatagacca tggaaagtct accttagctg atagattaat acaacaaact
     4561 gggcttgtta gtgaaagaga catgaaaagt caattacttg acaatatgga ccttgaaaga
     4621 gaaagaggaa tcactataaa gcttcaaaac ataagattaa tgtataaagc gaaggatgga
     4681 aatgaatatt atttaaatct tatagataca cctggacatg tagactttaa ctatgaggta
     4741 tcaagaagtt tagctgcatg tgaaggagca ctattagtag ttgatgcagc tcaaggtgtt
     4801 gaggcacaaa ctttagccaa tgtttatctt gctatagacc aagatttaga aatattacca
     4861 ataataaata aaatagattt accaagtgca agaccagagg aagtaaaaaa tgaaatagaa
     4921 gatttaatag ggcttgattc aagtgaagct cctcttattt cagctaaaac tggtttaaac
     4981 atagaagatg ttttagaaga tattgtaaaa aatgttcctc cacctaaagg agataatgaa
     5041 gctccattaa aggcattaat attcgattct tactatgatg cttacaaagg tgttgtagct
     5101 tatgttagag tatttgaagg aactgttaaa aagggtatga caataaaaat gatgaatacc
     5161 aataaaaagt ttgaggtaac tgaagttggt gttatggctc caggtcaaac tgaacttagt
     5221 gaattatcag caggtgatgt tggttatatt gctgctagta taaaagatat aagaagttgt
     5281 cgtgttggtg atacaataac agattcaaat aatcctacag aagaaccttt accaggatac
     5341 aaaaaagcta ctccaatggt atattgtggt atatatccag gagaaggaga aaagtatgag
     5401 aatgttagag atgctcttga aaagcttcaa gtaaatgatg ctgcacttga atatgaagct
     5461 gagacttcag cagcactagg atttggtttt agatgtggtt tcttaggtct tttacatatg
     5521 gagataatgc aagaaagact tgagagagaa tttaaccttg atataattac tacagctcca
     5581 tctgttatat atagagttac aaaaatggat ggagaggttg taatgataca aaatcctgca
     5641 aacttaccag aaccatctga gataaagatg atagaagagc ctatagtaaa aggagatata
     5701 atagttccta aagactatgt gggtgttgtt atggagcttt gccaggaaag acgtggaaat
     5761 atgttaaata tggaatatat agatgataga agagtaatgc ttcactatga ccttcctctc
     5821 aatgaagttg tttacgattt ctttgatgct ttaaaatcaa gaactagagg ttatggttct
     5881 cttgattatg aggttaaagg ttatgtagca tctacacttg taaaacttga tatattaatc
     5941 aataaagagc aagtggatgc acttagtttt attgtccatg agacacgtgc tttccctaga
     6001 ggaaaggcaa tgtgtgagaa attaaaagga gaaattccaa gacatcagtt tgctatacca
     6061 atacaagctg ctgttggtaa taaggttatt gcaagagaaa caataagcgc tctaagaaaa
     6121 gatgttcttg ctaaatgtta tggtggagat atatctcgta agaagaaact tcttgaaaaa
     6181 caaaaagaag gtaagaagcg tatgagacaa attggttctg ttgaagttcc tcaaaaagca
     6241 tttatgtctg tgcttaaatt agatgagtaa atccttataa atttagataa agatatttaa
     6301 aagctagagt gattttagaa ttatttctaa attagtctag cttttttatg gtatatttta
     6361 agtaaactca tagagaatat aagtaagaat attaaagaag aataaaaagg tgatatttat
     6421 gattaatata gaaattccta aaaaagtaga ctatataatt aaagaattag aaaagaatgg
     6481 ttatgaagct tatatagttg gaggatgtgt tagagattgt ttattagaaa gagttccaaa
     6541 cgattgggat ataacaacta gtgctagacc agaagtggta gtagaattat ttgaaaaaac
     6601 aattccaact ggtatacaac atgggactgt aacagttatg attgaacatg aaccatttga
     6661 agtgacgact tatagaattg atggaaatta tagtgatggt agacatccag attcaataga
     6721 atttacaaat aacatagtta aggacttgtc aagaagagat tttactatca attcaattgc
     6781 atacaattca aagacaggat tagtcgaccc atttaatggc tatgaagata tacaaaataa
     6841 gtatatacgt tgtgttggaa atccagtaga tagatttgaa gaagatgcac ttagaatgct
     6901 tagagcagtt agattttcag cacaactcaa ttttaaaata gctgaaggta ctaagcaaag
     6961 tattcataaa aaagcagatt tgataaaaaa tgtttctatt gaaagaatcc agacagagtt
     7021 taataaaata ttagtatctg attcatctaa attaaactta ttaaaatcaa caggtttgtt
     7081 gaaatttata attcctgaaa tatgtgaatt agaagatgtt actcaacaca atccatatca
     7141 catctatgat gtacaaaaac atactttaat agctacagaa gtaattgaag atgaactgta
     7201 tttaaaactt acaatgttgt ttcatgattt aggtaaaaaa gtaactaaaa caactgataa
     7261 aaatggtgtt gaccattttt atactcatag tagagaatct gtaaagattg caaagaagat
     7321 tttgaaaaga cttaagtatg ataattatac tattaataaa gttttaatat taatacaata
     7381 tcatgattat agaatagaac ctaaaaggaa gataattaaa aagttattaa ataaacttga
     7441 agatgttgaa ttatttgaag atttaataaa agttaattgg gctgatacac ttgcaaaaaa
     7501 tccaaagtat gcaaaacaaa agatattaaa tcttattgag tgtgaaaaag aatttaaaca
     7561 tataataaat caaaaggagt gctttaatct taaagattta gctattaatg gaaaagattt
     7621 gatatctata ggtataaaac caggtaaaga tataggatat attttaaata agatgcttga
     7681 aatagtcata aataatccag agttaaatga aaaagaaata ctaaaagaaa aagcattaaa
     7741 tatatataca ttttagattc aaatataaaa aatttaatta ctttaaaaaa catagaataa
     7801 aatacttatt tagataaaat aaataatttt tagagaatat tttagaagtt acgattgtat
     7861 gatttttaaa tgcataggca tttactctag gactatagac taatataaaa aaaaactttg
     7921 ggaatactaa aaccataaat ttataaaatt aatattttat atactgtaaa acagtgagga
     7981 gggacagtat gcatactcaa ctacaaaaga ctattggtct ttcagcagct ctttctactg
     8041 ttgtaggtat ggttataggt tcgggagttt tttttaagcc acaagcaata tacactacaa
     8101 ctaatggagc tccaggtcta ggtattatag cgtggctttt aggtggtttt ataacaataa
     8161 ctgctgggct tacagctaca gaaatttcag ctgctatacc aaaaactggt ggtatgatga
     8221 tttatatcga agaaatatat ggagaaaagt taggtttttt aactggatgg atgcaaactg
     8281 tattattttt cccaggtaca tcagcggcat taggagtaat atttgctcaa caagcatctg
     8341 aacttttagg aatgagccca aataatatgg caaatgtact tcctatagca attggagtta
     8401 tactattttt agcgttatta aatataatag gttcatcctt aggaggaaaa gttcagacag
     8461 tagccactat tggaaagatg atacctttaa ttttaataat agtctttgga tttattaaag
     8521 gtcaaagtag tgaagtatta aatccatttg taggagatgg tgtaaatgca tcaaatgcac
     8581 ttggacaagt attaatagct actttgtttg catatgatgg ttggataaat gttggagcta
     8641 tatcaggaga aatgaagtct ccagagaaag atttaccaag agcaatagtt ggtggtttat
     8701 cattagttat ggcagtttat attataataa atatagctta tctttgggta gtaccagcaa
     8761 gtgaattagc aacagttact tccccagcta cattagtagc aacaagattg tttggaaata
     8821 taggtggaaa agtaataact gtgggtatat taatatcagt atttgggaca ttgaatggat
     8881 atttattaac aggttcaagg ataccttata cattagctga aatgggaact ttaccagcat
     8941 ctaaaactct tttaaaagta aattctggag gttctcctgt aaattcaata ctacttataa
     9001 ctgtgttagc ctgtgtatat gcattatctg gtcaatttaa tcttttgaca gacttaacaa
     9061 tattttcaat atgggtattt tatgtattga cttttatagg tgttatgagg cttagaagac
     9121 aaaagccaga tttacacaga ccatataaag tccctttata tccaataata ccaattatag
     9181 ctatattagg tggactgttt gtaataataa atcaaatatt gacttcaaca gtcatatctt
     9241 taggcggaat atttataaca ctattaggtt taccagttta ttattatatg aaaaaaagat
     9301 aactacttaa tttaagttag ataaatttgg gtaaaggtga aaattaactt ttatccaaat
     9361 tttttatact gttatacaat ataagtatta tatattgctt gatgtgctat tttgtttgat
     9421 ttataattta gtaattgatg ttttaagata atttaagaaa tgaggagtga aagatgctag
     9481 gactttatgt acatattcca ttttgtgtga aaaaatgtaa gtattgtgat tttaattctt
     9541 ataaaatgga catagattca aaaaaaagat atatagaaga cttaaaaata gaaatggaat
     9601 tatatagtaa taaattatat aaagataata aatataaaaa taaagaatgc tgtagtctaa
     9661 ataaaaatga caaaataacg agtatatttg tagggggagg tacacctagt atactaacct
     9721 ctgatgaaat aagagaagta tttataagta taaaagaaat gtttgatata gatgagaatg
     9781 cagaaataac tatagagtgt aatcctggga cattaacatt agaaaaatta aaaactatga
     9841 aagagattgg cataaataga cttagtatag ggctacaagc tattcaagaa aagcatttga
     9901 actttatagg aagaatacat acttatgaag aatttgagaa aaactataaa gatgcattaa
     9961 gtgtaggttt taaaaatatt aatatagatt taatgtacag tcttccaaat caaactctat
    10021 gtgattggaa ggaaactctt gaaaaagttg tacacttaaa tccaacacat atatcagctt
    10081 attcccttat actagaagaa ggaactgaac tatacaatat gtatgaaagt aataaatttg
    10141 aacttataga tgaaaatgta gatatagaaa tgtatgagta tacaataaac tatttaaagt
    10201 caaaaggata taatcaatat gaaatatcaa actactcaaa agaaggctat aattgtgagc
    10261 ataatatttt atattgggaa tgtgaacatt atatagggat tggagcagga gcttctggct
    10321 atattaatga gaacagatac aataatgtag aatctttaga agattatcat ttaagtttgg
    10381 taaaaagaga aaaaccaata caagaaaatg aaattctttc tgagaaagat atgatagaag
    10441 aaaagatatt tatggggctt agaatgaata aaggcataaa atttgaagat tttaaaaaaa
    10501 aatttggaat agattttaga gagaagtata ataagcaaat agaaatgcta ttagctagaa
    10561 agcttataaa tcagagcttt gaaggtatac aattaactca aaaaggaaga gaaatatcta
    10621 atagtgtatt tatagaattt atggaataat ttttaaggtg ttgacaaaat aaatttataa
    10681 tggtatataa tatatataat ctttttagca ctcgaactta gtgagtgcta acagctagga
    10741 ggtataataa tatggaatta aatgaaagaa aattaaatat cctcaaagct atagttaaag
    10801 attatataga aacagctgaa gctataggtt ctagaacaat atctaaaaga catgatttag
    10861 gtgttagtgc tgctaccata agaaatgaaa tggctgacct tgaagaatta gggtatttaa
    10921 ttcagcctca tacttctgcg ggtagagttc catctgaaaa aggctataag ttatatgtaa
    10981 actctcttat gagtaaaagc gaattggatg ataatgataa gattcttatt gaacaatgta
    11041 tgaatcataa tataaatcat ataaaagaat tgattcatga aacttctaag ctattatcgc
    11101 aactaacaaa ctatacaact gtagcagtta ctaagagttt aataaatcaa agtgttataa
    11161 agcacataca gttggttgct atgaatgaca ataatatttt acttatagtt gtaacagata
    11221 aaggggactt aaaaaaagct aaccttacaa ctaatgtata tttagatcaa tctaagttaa
    11281 atttgatttc tgataatctt acaaggaagc tcttaggtaa aagtataaca gatttggatg
    11341 ataatctaat tgcttttatt aaatacgaaa taagtgagta ttctgggctt atagatgagc
    11401 ttttaaatgc tttgaactca aatatgaaag aagaagattt ttctctatca ttaaatggag
    11461 ctactaacat atttagttat ccagaattta atgatgtatt aaaagcaaag tcatttttaa
    11521 atatgttgga aaaaaaggaa acaatagctg acataattaa atcaaaggga atacaaaaag
    11581 acaatctaaa tataataatt ggtagtgata atgattgtga actggcacag gattgtagta
    11641 tagttacagc aacttataat gtagatagag acttggttgg gcgaataagc tttataggcc
    11701 ctaccagaat ggattatgct agaatttact ctataataaa ttatatgagt ttattaatta
    11761 atagaaagta aagaaatttt aaattgcgag gtgtaaagtc ttggataaaa aaaatgagca
    11821 acaggaagta agagaagaaa atgatacttc tattaaccaa gaatcggaaa ctcaagtaga
    11881 gttagaagag gaagttgtta atgaagaatg tgaaacatca agtgaaaaaa ctgatgaaaa
    11941 agaagttgat gatgaaaatg taacagatat aaattctaag ttagcagaaa aaaaattgca
    12001 ggatgagttg gatgaattaa atgataaata tcaaagactt caagccgaat atgcaaacta
    12061 cagaagaaga actcaacaag agaaagagac aataggcgta tttgcaaatg aaaaaataat
    12121 aactgaattg ataccagtta tagatagtat ggaaagagcc ttagatgcat gtgaagataa
    12181 ggaagatact atgtataagg gtataagcct tgtacataaa caattaatag acactttagt
    12241 aaaatttgga gtagaagaaa tagaagcaga atctaaggaa tttgacccta atctacatct
    12301 agcagttatg caagaaagtg tagatggagt tgaagcaaat caaatagtaa tggtacttca
    12361 aaaaggatat aagctaggaa ctaaagttgt aagaccttca atggttaaag tttcttgcta
    12421 agtataaatt aaaggttaaa ttatttaacc taatataaaa tattaaaata agtaaaactt
    12481 aattatataa ttactcgagg aggattttag tcatgggaaa aataatagga atagatttag
    12541 gaacaacaaa ttcatgtgtt gcagtgttag aaggtggaga agcacaaata atagcaaata
    12601 gtgaaggtat gagaactact ccatcagtag tagcatttac aaaagatggt gaaagaatag
    12661 ttggagaacc tgcaaaaaga caagcagtta caaatgcaga taaaacaata acttctataa
    12721 aaactcatat gggaactgat tataaagtaa atatagatgg aaaatcatat actccacaag
    12781 aaatatcagc aataatatta caaaaattaa aatcagatgc agaaagttac ttaggacaaa
    12841 cagtaacaga agcagttata acagtaccag cttactttac agatgctcaa agacaagcaa
    12901 ctaaagatgc tggtagaata gcagggcttg atgttaagag aataataaat gagccaacag
    12961 cagcagctct tgcttatggt atggataaat tagaccaaga aaagaaaata ttagtatttg
    13021 acttaggtgg aggaactttt gacgtatcta tacttgaaat aggagatgga acttttgaag
    13081 ttttagctac agctggtaac aatagattag gtggagatga ctttgaccaa atagtaatag
    13141 attatttagc agaggaattt aaaaaagctg aaggtgtaga tttaagaaat gataaaatgg
    13201 ctcttcaaag attaaaagaa gcagcagaaa aggctaagaa agaattatca tcaacaatga
    13261 gttcaaacat aaacttacct ttcataactg ctacagcaga aggaccaaaa cacttaaata
    13321 tagatttatc aagagctaaa tttgaagaat taactagagg tttagttgaa aaaactatgg
    13381 aaccaactaa gacagcttta caagatgcag gactttctac aggtgatata gatgatgtat
    13441 tattagtagg tggttctaca agaataccag cagtacaaga agctgttaag aagtttatag
    13501 gaaaagaacc tcataaaggt ataaacccag atgagtgtgt tgcagcaggt gcttctatac
    13561 aagctggagt tttagcaggg gatgttaaag acttattatt actagatgtt actccattat
    13621 ctcttggtat agaaactatg ggtaatgtaa tgactaagat aatagaaaga aatactacaa
    13681 taccaactaa gaagtctcaa atattctcaa ctgctgctga taaccaaaca gctgttgata
    13741 tacatgttct tcaaggtgaa agaagtatgg cttatgacaa tacaacttta ggaagattcc
    13801 aattaacaga tataccacca gcacaaagag gaatacctca aatagaagtt acttttgata
    13861 tagatgcaaa tggtatagtt aatgtttcag ctaaagattt aggtacagga aaagagcaaa
    13921 aaataactat aacatcaaac actaatttat cagaagcaga aatagagcaa aagataaaag
    13981 aagcagaaat gaatgcagaa gctgacaaac aaaagaaaga aaaaatagaa gcattcaatc
    14041 aagctgaatc tactatatat caaactgaaa aaactttaaa tgaacttgga gataaaataa
    14101 gttcaggtga aaaagaggat atagaaaaag ctatagcaga cttaaaagct gtaaaagata
    14161 atcaagatgc tacagcagaa gaacttaaga aagctacaga tgaagtaatg actaagttcc
    14221 aaaaagtatc tcaagaaatg taccaaaaag cagctcaaga acaacaagcg gcacaaggtg
    14281 cagaacaagc acaagacaat ggacctaaag atgacaatgt agtagatgct gactttaaag
    14341 aagtagatga agataaataa gctatataat atgtaacact aaatgataat tggaacatat
    14401 atgatttgtg aaaatcatat agatgttaaa gatatatgga caatatacat cataaagaat
    14461 ataatatatc atagattata taacttaaag tagaatataa gaattaatga tagcttgtag
    14521 tttattattc tacaagctat cgttttgtaa aatgaaggtg gtgtcaattt ttgagtacaa
    14581 aaagggatta ttatgaagtc ttaggtatca gtaaaggtgc agaagctcaa gagataaaaa
    14641 aagcttatag aaaattagca atgaagtacc atccagatag aaatcctgga gataaagagg
    14701 cggaagaaaa atttaaagag ataaatgaag cttatgaagt tctatctgat gatacaaaga
    14761 gaaaaactta tgaccagttt ggacatgatg ggctaaatgg tcaaggcggt tttggtggtc
    14821 aaggaggatt tggcggtcaa ggctttggtg gttttgaaga tatgttcgga gatatatttg
    14881 gtgacatgtt tggaggaagc ttcggaggtg gaagagcaag aagaagaggg cctcaacgtg
    14941 gtgcagatat aagacagagt gttactatat cttttgaaga agctgcattt ggtaaaaaga
    15001 tgtctataaa agtaaataga agtgaagaat gtgaagaatg taatggaact ggagcaaaac
    15061 caggaacatc aaagaaaact tgttcaactt gtaatggaac tggtcaagtt agaactgttc
    15121 aaagaactcc atttggtaat atagcaagtt caagaccatg tagtgcttgt aatggaactg
    15181 gagaagtgat tgaatctcca tgtagtaaat gtcatggaac tggaaataca agaaaagtta
    15241 agactataga agtagatata cctgctggta tagatgatgg tcaaatgata aaactttctg
    15301 gtcaaggtga agtaggagaa aaaggtgctc caagaggaga cttatatatt gtagttaatg
    15361 ttaagtcaca tccactattt actagagatg gaaatgatat ttattttgaa atgccaatta
    15421 catttgttca agcaacttta ggtgatgaga tagaagtacc tactttggat ggaaaagtta
    15481 aatatagtgt gccagagggg acacaaactg gaactgtatt tagacttaaa gagaaaggaa
    15541 tccctagaat tagaggtaat tcaagaggag accaatatgt taaggttgta gttgaaattc
    15601 ctaaaaaatt aaacgataag caaaaagaac tattgagaga atttgcgaag gagtgtgggt
    15661 cgaacgtcca cgaaaagaag aaaaccttcg gacaaaagat agaagatatg tttaagaaaa
    15721 agtagttaaa gtagccaata tataatcata tttttaaaat cttagttatt tataagattg
    15781 tcaaaggaga tattatgatt tttatattgg ctatttttgt ataaaaaata aatgtgcata
    15841 aaataaaact gaatataaat aattttctga aaaatacttg tcctaaaata tataatatgc
    15901 tataatataa tcaaataaaa gaaaggggtg attccagtgg gaacggatgt ggcactgcca
    15961 aatgatgaag aaaactttat tgtaatatac aaaataaaat tagatacttt tagtgctaga
    16021 ttaagtactg gaaaaactca tgagctggga taattattgt aattacctag actcaaactt
    16081 ttagtagtaa aatagtaata ttatatagac aaggtatcta atttttaaat cttttgtatg
    16141 aattaaaatt tttataaagg gtatatctga ttagaatgta attagggaaa cctagttgtg
    16201 aattactttt agtatataca tgtgtaaaga aatatgtata tggtattggt tattgtgcta
    16261 gatgtgtatg taaaggaata tgtgtctagt tgggtatatg taaagaaata tacttataat
    16321 ctatgaaaaa tttttagtat aaattgctaa aacattgaga ttgtttttta tagaaagtta
    16381 gtttatacca actaaaaatg tgcttaagat ttgtttgatg tttaattata aataaggttg
    16441 tagataaaaa aataagtaaa gacaaaggtt taaaatactt gctttaaata tagtttgttt
    16501 tgaacacttg ccaaattaaa ataattaata aaatagacat cttctcatag taaaatatac
    16561 tgtgagagga tgtttttgct ttgttcataa acttttatga aaaatttgca tagtgtcaca
    16621 ttttaatata ctatatatat aataaaatat agataaaatt aaatgattca aaagagaaag
    16681 gtgaaaagag atgtattata taggtgtaga cataggagga acaggtatac aagcaggagt
    16741 agttgataac tatgggaaaa taatttttag gtcagagtgt aaaacagtaa ttgaaaaagg
    16801 ctttgaagga atacttaatg acataaaaat aatgatttat aagttgttgg aagataataa
    16861 acttactatg agtgacataa aatctattgg atttggtgtt ccaggtttta taaataaaga
    16921 aggattagta acttgtgtaa atttaaaatg gaataaaaaa gcttttaata aagagttaaa
    16981 aagaagattt ccagatgttg aaattcatgg agaaaatgat gcaacagtag cagcacttgg
    17041 agaagcaaag tttggaagta tgaaaggtgc taatgttgga gtattatata ctttaggaac
    17101 tggagtaggt ggaggaatag taattaatca aaaagtcttt tctggagcac atggattggg
    17161 ttcagaaata ggtcatcaaa ttataggaga aaactatttt aattgtaatt gtggaaataa
    17221 tggttgtgta gaaacttttt gttcagcaac tgcaattata aagtattctc aaaaactgat
    17281 agaagaagga gaaaagagta ggattttaga tttggcagag ggaaatttag aaaatgtaaa
    17341 tgcaaagatg gtgtttgatg catatagaga aaatgattta gtggcaatta aagtaataaa
    17401 tagatttaaa gagtatttag caaaaacttt tgcaaacaca ataaattctt tagacccaga
    17461 aattatatct ataggaggag gcatttctaa atctagcgat ataatacttg atggaataga
    17521 agatttggta agaaaatttg tattatacaa aacagaagat atagctacaa ttacatgtgc
    17581 aactttaggt tcagacgcag gaattatagg agcagctttt ttataatgta aatgaactgc
    17641 ttattggagg cgtgatgata tatgggtaaa acaaatgcta gaagaacgct ttttttgata
    17701 gcaataggtt caggaactat gctgaatcct cttaattctt ctatgatttc acttgcttta
    17761 catagtatac aaaatgattt tcatattagt tttacaactg tatcttggat tgtttcagca
    17821 ttttacctag ctagtgctat tgcacaacca gtttcaggta agataggaga tttaataggt
    17881 agaaaggtct tatttttgag tggtttgatg cttgtaattt tatcagcatc catagtacca
    17941 cttgttcaat cattctttat attgattttt ataagagtaa ttcaagcaat tggaacaagt
    18001 accctatatc catctggagt tgctcttata caaaataata taaaagaaag acaatcttct
    18061 gcattagcag ttctaaccat ttttgcttca actacagcag gattaggtcc gacacttgga
    18121 ggattattgt tggacttagg aggatggcat gctatatttc ttgtaaatat acctgttgtt
    18181 ttggtttcta tatgcttagg gtatttttta ttcccaaaag aagtaaaaga aaagaaatct
    18241 ataaaagaaa ctttaaaaaa tgttttgtca agattagata ttattggcat acttctattt
    18301 tcaattgcaa tgatttttat attactattt ttgctatcta tgaaggagtc ttttaacttg
    18361 gaacaacttg tatttggtat aatactgatg tgtcttttta tttggcatga attgagaaca
    18421 aaattgccat ttatagatat taagcttttt gtaagtaatc ctaaattgtc aaaagtttac
    18481 ttgcaattta ttatattaaa tttctttaat tatattttgt tttttggtct tcctagttat
    18541 tttcaagatg ccttacatta tagtgcaaag tcgactggat tatttatgct atttatgtct
    18601 ggtataggta tatttatatc tccattaact ggaaaatgga tagataaatc tggaactaga
    18661 tttcctcttg ttacatcatc aatctttatg tttattagtg cagtacttct ttcagtagtt
    18721 tttatccata tacctgtaat aggaaagggt attatattat cattagcagg tattagttat
    18781 ggagttggta atgtagccct gcaatcctct atgtttgaag aaagtcctcg tgacagtata
    18841 gggacagctt ctggtctgtt tcaaactagt cgttatttag gttctatttt agcaactgtt
    18901 ttacttggaa tggtatttga agtaaatata acatcagaac aatttcagat attaggttat
    18961 gttatggtgg tcttaggtac aataagtttt ttattaaatt ttatattaaa gaaagaatta
    19021 agaaaagtag aatagtggat ttatggattt aataagtcta ataactgata agtttaaaaa
    19081 tattgtttgt aaaacataac tggtttgata tttattaatt ctaagttttg aagcatagag
    19141 tactcgataa gtatacaata ttttgaatta aaattaagca gaaatttgaa ctagtctttc
    19201 aaatctctgc ttaatttagt agttaaattt ttttatagag aaaataagat ttgacactta
    19261 gataaaaaat cattgcattt tcaaaattct ttaaatcaaa cccaagtatc tcattaatct
    19321 tttccaatct atatactagc gtgtttctat gtaaaaacat actagtagat gtcttagaaa
    19381 tatttaaatc attatttata aattttattc ctgtatatag aagttcttcg tcaatagatt
    19441 taatcttatt aaaatctatt aatttattga gtatattatc ctcattaatt aaatctaaag
    19501 ttttatatct aataaagtca aacaaattta aaaacttatt ttcagcgttg tcttttataa
    19561 tatgaggtag taaatcagaa cataactgta atctaaaatc aaaatcagct ttactatcta
    19621 attcaccaag ataaaaaata taagtacttt gataagtttc agtttcaatt atattttgtg
    19681 tagttacatt aatatctaag ttatatttag aatttactat aaaaaaacca ttgtgttgta
    19741 ttatatttat atcttcaaat aaattataaa aaatattttt tagatattca aagtctatat
    19801 gagattggta aattaaataa aagttgcctt ttaaattatc gagattattt ttatctagaa
    19861 aatcaataac ataaatagca ttattgaaag taactaaatg gctactagca tctaactttt
    19921 ggttttcata tggatagata tttatttttt tattaagctg tctttctaaa aaatctttta
    19981 actcttccat aaagtctcct taaaaataag attatattct tatcttatag ctaaagtagt
    20041 ttctttgtca aatatgtgta ctctactatt gtcaactgaa agtgttaagt catcaccaac
    20101 attaattctg tttttactgt caaatctaat tgttatcgta ttttcgccta gttttaagtg
    20161 agcataagtt tctgctccca taagttcttt tatttcaatt cttgatttaa aacaagtatc
    20221 tggattagat ttaataaaag tatcttctac atgaatatct tctggtctga tacctataac
    20281 aacttcatta ttaatataat tgtcttttat taaatcatag tgtttttctt tattcaattt
    20341 aagcttaata tgttcatttt gtgcataaat ttcatcattt tcttctatta atattacatc
    20401 aataaaattc atctgtggtg ctccaataaa tcctgcaaca aatatattag ctggataatc
    20461 gtatacatct tgtggagttg caatctgctg aactactcca tccttcatta ctacgattct
    20521 atcagccata gtcatagctt caacttggtc gtgtgttaca tagataaatg tagttccaag
    20581 ctgttggtgt agcttagtta tctctgttct catagcagtt ctaagttttg catctaagtt
    20641 ggatagaggt tcatccatta agaatacctt aggatttcta actattgcac gtcctaaggc
    20701 aaccctttgt ctttgtcctc cagataatgt tttaggtttt ttatttaaaa gaggtagtaa
    20761 gtctaatatt ttagcagctt ctttaacttt tttgtctatt tcatctttag gcaaatttct
    20821 aagtttaagt gcaaatgcca tgttttcgta aacagataag tggggatata aagcatagtt
    20881 ttgaaaaacc atagctatat ctctatcttt tggttctata ttattgacaa gtttatctcc
    20941 aatgtatagt tctccttcag agatttcttc aagaccagca atcattctaa gtgtagtcga
    21001 tttaccacaa ccagatggtc ctactaaaac gataaattct ttatctttaa tgtctatatt
    21061 tatatttttt actgcgttaa atccatttga gtaaagtttt gatatatttt ttaaaattac
    21121 ttctgacata atatcctcct tgatatttaa attttaatta tatagtatca aattttttta
    21181 ttatattaaa tgtgtaaaat gactaaatgt atttgtttaa tatgtatatt tagtttttag
    21241 caaagaataa aactaacagt agaatatatt taaaaaatta aaaaacaaaa ttaaatttat
    21301 tatcaaaaaa tcattttatg atatgtttta tttttatatt acaaatagag aataatgaat
    21361 tatactagaa agtaggaggt gaaaatatga gcagaatttc aatttttatg gaatcatgta
    21421 atggcaaatt tccaaatgaa aattcaatgt tgtcagtttc ctttataaaa aatattttaa
    21481 atgcagaaaa caaagatttt gctaaaaaca tatttaacta tggggaagaa agaaaaaaca
    21541 ataagcaaat aaaggatata aatacagcca tttacatacc aaatcttata agaagcaaaa
    21601 atgagttact tgttgatgga gatataatat tcaatataag tttttataat tattctatgt
    21661 tcagtaaatt atacaatgga attttaaaag taaaggagct agaatataaa ggttatagat
    21721 ttaaaataaa aaatataaaa atacataaag aacacgagat aaaagaaaat ggtgttatat
    21781 ttaaaactat gtctcctata atagtaaaga ataaagaagg taaatattta gatgtagaag
    21841 attcaaatta tatagaatgt ttaaactata tagctaatct aactctggag agtataagag
    21901 gtagtgggct tagaaagcca ttggaattta tacctattaa cttcaaaaaa agagtgttaa
    21961 aagaaaagat tcgtggattt aaagtgagag aatattacta tataaatgct tatgcaggaa
    22021 catttttttt aaaaggagat atggaagatt taaatgcact gtataaaatg ggaattggat
    22081 atagaaggac agaaaatgca ggaatggttg atatattaaa gtagcgaggt gagagaaata
    22141 aaagctaaat tttatagatc aggtgatatt gtaagagata ttggcattgt ttacttttat
    22201 gaattactaa tggatttaaa aaacgaacta gaaaaaaatg attataagct aaaatttact
    22261 tgtgagttaa atagaaatta tttatcttta gaatctgcag aatatataga ccctaagtat
    22321 atatctgatt atatattaga aaatcgactt tttaaggtat ttaaaaatgg gaaaaaggaa
    22381 accttagaaa aaatatttag taatatagat aatttaacgt atgtaaattt tattgaagaa
    22441 ttagataaat cttctgcaac tgctaaacaa aaggaagata ttaaaaaaga ttttaaaaac
    22501 aggaggtttc catatgttag aaatagtggt aagtatggat taaacacgag tttagaaaat
    22561 atggaaacaa atgtaaaaag aatagtagat actgtaatta aatcaaatat agagatagat
    22621 gaaatagata aacttgattt gacacaatat gaagaaaaag atagtgtatg taatgtttgc
    22681 aatataaata aaacaacaaa actagatatt gatttaagag aacgaaagga ctctaagtat
    22741 aactttttat ttagaggtgc agaaaaatca ggctttaaaa gaagtggaca agttgaaagt
    22801 aatatttgtt ttgagtgtga atttttcaac ttaatgtgtc ttttatatat aaatttaaaa
    22861 agaccaatgg tttttgcata tacgaatgat ttaagagaat tagcattttt aaatcataag
    22921 ataatgctta aaagaaaaat gtattcagat aaatcatttt ataaaaaact tttgcatgaa
    22981 aaaataagtt caattagact atatagcttt gatattgata cgaataaagg tataattcta
    23041 aagtttgatt ctattataga gtataaagaa ttattaaaaa aaattgaact tatagatatt
    23101 atagataatt ataatttttc aagagagcca ggtaatacta gaaatttggg taaaagaatg
    23161 attgataatg ggaatttatc aaatttaaaa gaattattac ttgataatat aagtgtttta
    23221 aagcaatcaa ctggaacttc tcgagaaatg gattttgtat ctagctcata taatatcggt
    23281 ttatatataa aattgtgttg gattgtagat ggaggggagg agtataaaat gaaaaactat
    23341 atggaaagta atttaatata ttcaagagta ggtaaagact tatttaataa aatgacagat
    23401 gaatccagaa gaaaaaattt ttctatgaaa gtgattcaac tacttaagtc taatgataga
    23461 actcagctat ttcaaactat aatgcatgtg ttagtttcta atggaatctt aataggagaa
    23521 gggtttgtag aaggtctaat gcagagttct gaattagaat taaatacgaa tgtaggtcta
    23581 tttattcaag aaatcatgaa ataaaaaagg gggaaaattt aaaatgaatg aaaaaagagt
    23641 aaaaggagta acattaacta tactgacaga aagcccagtt ccactttcat atgaccaagg
    23701 gtatggaaat tatacaccaa taaaaaaaga acaatataga gaaaaaatac atgcaaaaac
    23761 tagtatagcc acaataacat atgatttaag aagaatgctc caccaagaat atggttggaa
    23821 tttaagtaat attgtttttg gaaaaaaagg aaatatatat ccatctatta agaaaaatgt
    23881 aggatgtgta gatgaaaatg gattagagac tgatgtattt ggttatttaa taccacttaa
    23941 agataaaggt tctataagta aagcttctcc acttagaata atacctttta ggtcattaaa
    24001 tccatataaa ggttcaacac agctaataac aaatagaggc tttttaagta gtgaatttgg
    24061 tagaaaatat tatgatgaga aggaagaaaa tgaagtacct agagatgaaa actttccaac
    24121 atcacaagca ttagcaatag aagagacttt atcagattac tacgtttata caataacatt
    24181 ggagcttgat agaataggag tagtagaagt agaagatgga aagttacttt taccagaaga
    24241 aagaaaattt atgagtaagg agttaagaga aaaagcagta aaagatatat tagatgcaat
    24301 tactgtgttt acaagaaaca taaaacattc atcagtacta ttaaaaccac ttgcagtaat
    24361 aggtggagct tttgataaag ttgtaccatt tttttgggat gatgtagatt ataatgctga
    24421 tagtggtgag ataaatttag agggagtcat agaaactata gaaagttata gccttaaaga
    24481 aagtaacaca atacttgcta tcaatgatag attaaaaatt tctaataaaa aggaattaaa
    24541 taagtttaat ttaagtaaat accctgtaaa agagattaaa aatctagcag atagattgga
    24601 aattggagaa gataatatgt ggtatttaaa agagtaggag gttttttgaa ttatgaaagt
    24661 attacaatgt aaacttaagc aaccaactgc tcactataga gacccaaaag tatttcaaaa
    24721 tgaatatata agtactttaa atttaccatc taagaccaca ataatgggaa tgataacgta
    24781 tttatgtgat agaagattaa actctgatat agatatagga ataattggaa cacatcatca
    24841 tagagaacta gaattttcaa gaggagaaaa cattgatttt tggaatgaat atataaaaat
    24901 gggaaaaggt aaagataaag aaaagttttt gcttaaagga aactactatg attactataa
    24961 agagcataaa gctcaaaata gcatattaaa ctatgaagtt cttaaagaag tagaactgac
    25021 tatatttatt tcttgcaagg atgatgaaga acttgaattt attagaaaaa agcttgaaag
    25081 tccatgtaaa tatgcaaatt taggaagaaa agaagatttt gtaataccaa gtgaaaaagg
    25141 gtgttttgtg aaagaagtta agttaaaaga ggttatacct atgaatactc gtgatgctat
    25201 aaaagaaaat ataaaattaa agaatacata tgtaagagtt gacttaagag ataaagagaa
    25261 tgtcgagact ataataaatc aaggtgtatt gattgcattg cctcataaat ataaagattt
    25321 agaagcaaat agagatgata gagtttatga gttttgccat tatatatatg ttgataatga
    25381 tggtatatat cctaaaaata ttaaggtaaa tgtatgtatt gatacaaaag aagtttttac
    25441 atggctttaa attattttga aagataggtg tttatcatga aaaatatcat gcaaaaagaa
    25501 atattagcta agtcatacaa tttaagaact aatcaacaag aacaaacatt agttgaacat
    25561 attaaggatt tatttgaagt attagaatct atattagaat taaatctata ttcagataaa
    25621 gatgtagaga tactaaaaat atgttgtgct ttgcacgatt taggaaaaat taattcaatt
    25681 atgcaacaaa aaatggagat taataataaa atatcgtata gttgctcaga agaagagagg
    25741 aaaaagttag agtctgacaa aaaatcttta aaaaagatag caagacataa tatattttct
    25801 ggagcatttt taaaagatat attagaaaaa atgaacttgt cagaagaaga taagttatat
    25861 atatataaaa gtataatgtt acatcatgga aactatgaag attatatgag gttaagtatt
    25921 agtaaagttc aagaagaaat ttatgagtat attgaaaaag gcattttaga aaaagaagag
    25981 tttaatctga aagatataga aagttatata aatagcattt taaatgtaga ctttaaattt
    26041 ggtgaagatg tattggatta tgattacata gataaattaa gtgaaagtat gtttatagac
    26101 agtgattata acaatggtca aatagatgat tcagttttaa attatagaaa gtttaagtat
    26161 attttatata aagggatgct gaacttaata gaccatagtg catcaagtag acagaaaggt
    26221 ataaaatttt ataacgattt tactgatgaa gaaattgata atatgatttt aaatgagata
    26281 tataagagtc agggtaattt ggaaaaaaat aatatagagt tcaatactat acaaaaaagg
    26341 ttgagagaac tttctggaag aaatgttctg actgttgcat ttacaggttc aggaaaaaca
    26401 gctgcagatt atagaaagac ttttaaaaga aaattctttt tagtgccaaa taaaatatca
    26461 gcagaaagtt tttatagaaa aaatattttt caaaataaaa atgatttaga tacaagaagt
    26521 agtaatgatt acattggatt acttcatgga gatataaact tatattcaga gaatgaagat
    26581 aatggagaac atgattttgt attgacatta agggatatag atttgagtat aaacttttgc
    26641 aaaccttgtg taattgcaac agttgatcag ttattactta gtatgtttaa atttccggga
    26701 tatgaaaaaa tattcgcagc cgtaaaaaat gcatctataa ctgttgatga agtacattta
    26761 ttggaaccaa agatgttttt gattttgata tattttatgc agtttgcatg caagtactta
    26821 gatgttgatt ttcacttaat gacagctaca cttccaaaat catataaaga gcaaatgata
    26881 aacaagggaa ttatttttca agaagaaagt aatgaaaatg ttactgataa aggagaaata
    26941 gtttttattg agagcaacaa ggaagaagag atttgtgaag gtaaagatgt aaaggtttct
    27001 tttataaagg aaaaagaaat caagtcaata gttgaagatg ctttagaaaa taaacaaaaa
    27061 attcttataa taaagaatac tattgattca gtcaatagaa catatgagtt tttaaaagaa
    27121 aatttatctg ataagtatgg tggtgtagat atagatgttt tacatagtag atttaagttc
    27181 aaagataaaa aagagaaata tagtaaaata ttaaatggag agggtgatat ttggatatca
    27241 actcaatcag tagaaatatc cttggatttg gatttcaata taataataag tgatttagca
    27301 actatggata gcttaataca aagaatgggt agatgcaata gaaataataa gtatgaatat
    27361 ggaaactttt atattctacc tagtgaagat aaaatttatg acaacaaact taagagcaca
    27421 actaaaaaca tcttaaagga catattaaaa actaactcta tttttacaat gggaattaga
    27481 aaaactattt tggatgatta ctatgataat agtgtagtca aaaaatattt tgaagagaat
    27541 tttataagtt gtgataaaga aattaagaat atttatggtg taaataaaga aatttttgat
    27601 ggattggatt taatttttaa ttttgaacct tacaaaaata ttgttgatag taagaaggaa
    27661 gcagctaaaa tttttagaga tgttgatgtt agttacaaaa ttattctgga agaagatttt
    27721 tataaggaag atagagagtt acaacaagat tcgattcaag tatcagggtt tatatttaat
    27781 agattatatt attatgggtt aataagcaaa gtagaaggat acatggtact aaaatctagt
    27841 agtaagtttg agtataatag tactgtaggc ttaattttga agtgagcata tgtttaaata
    27901 taatatacct ttagacattg aaaatacaaa aagtactact gtaagctcac tgtaaaaact
    27961 attttttaaa aggaaaaata agttgtgaga tagagtgttt acaagtgtat atagataata
    28021 aatttgaggt ttaagattaa ctaagtgggt ttcaggtaca tcgcgaaaat aattataagt
    28081 tggagatttt gtatgtttaa gattaactaa gtggatttca aatattgata tagtagatat
    28141 aatagaagtt ttattattag gtttaaaatt aactaatcgg atttttaaat attctgacta
    28201 ttatataagg atattattag attgaattta aaaccaataa tataaaacaa caaaatatta
    28261 tatttatgat ataataaaag ttatggaaaa acaggaatat tactatagag aagagaggta
    28321 aacttatgaa taattggata gaagtaacta taaaaacaac aacagaagca gttgaaccta
    28381 taacgaatat actatatgaa caaggagctg gaggagctgt aatagaagac ccaaaagact
    28441 ttttattcca aaagaaaaat gaactagact gggattatgt tgaagaagaa gtatttaaaa
    28501 agaatgaaga agatgatgtt cttataaaaa cttatgtttc tgaagaaaaa aatgtgatgg
    28561 aatttgtcga aataataaag caaaaagttt taggattaaa agattttggt atagatatag
    28621 gtgaaggaag tgtatcattg gaccaagtaa atgaagctga ttgggcaaat gcatggaaag
    28681 catactacaa accaacaaaa gtaggacaaa gggtagtagt aaagcctaca tgggaagatt
    28741 atgctatgca agagggggat ttaatcatag agcttgaccc tggaatggca tttggtacag
    28801 gtacacatga gactactagt atgtgcatta gagaattaga aaagtatgtg aataaagatt
    28861 ctaaagtatt tgatattgga tgtggtagtg gaatccttgc aatagcagca gctaaattag
    28921 gagcaaaaga agttgtagct gtagatttag atgaagtggc tgtaaaagtt gcaaaagaaa
    28981 atgttcttga aaataaagtt gaaaaaagtg tatctgtaat gcatggtaat ttaactgatg
    29041 taataaaaga taaagcggat gtaatagttg caaatataat agctgatata ataaagatac
    29101 ttgcaaaaga tgttcaaaac tttatgaaag aagatgctat attcatatct tcaggtataa
    29161 ttttggataa agtagaagaa gttaaagaaa gcttaattga aaatggattt gaaatagttg
    29221 aagttcaaaa attaggtgaa tggtcagcaa tagtttctaa gcttaaaaaa taagggatat
    29281 ggtgacgtat aatggataga ttttttgttg aaaaaaataa tataaatcta caagataaaa
    29341 cttgcactat agaaggtgaa gatgtaaaac atatttcaaa agttttaaga tgcaaattag
    29401 gtgagaaact tgaaatatgt gacaagaata ataatgagta tatttgtgag ataatgaata
    29461 tagataagag tatagttaat ttagaaattt tagaaaaagt tgatataaat agagaatcag
    29521 aacttaaagt aaggctatac cagggacttc caaaagctcc aaaaatggaa ataatacttc
    29581 aaaaattaac tgaagtgggt gtagaagaaa taatattagt tcaaactaag agaagtgttg
    29641 ttaaagttga tgacaaaaaa gaagataaaa aatttgaacg ttgggaaaga ataatttatg
    29701 aagcagcaaa gcaaagcaaa agaggtaaga taccaaaatt aagaggtgtt ttaagtttta
    29761 aagaagcttt agaagatatg aaaaaaaata gtgtaaatat ttgcccttat gaaaatgaaa
    29821 gaacagtttc aataaaacat gcactaaaaa aatgtgattc taatatagat agtgttggaa
    29881 tttttatagg tccagaaggt ggattttctg aagaagaaat agaacaaata caaaaaaata
    29941 attgtaatgt tgtatcattg gggcctagaa tattaagaac tgagacagct tctgttgtag
    30001 catcaacaat agctttgtat gaactaagtg atttaggagg agaaaaataa attgaaaaaa
    30061 gtagcttttt atacacttgg gtgtaaagtt aatcaatatg aaacagaagc tatgctagaa
    30121 ctatttgaga aagatggtta tgaacaagtc aatagtgaag agtatgctga tgtttatgtt
    30181 ataaatacat gtacagttac tcatatgagt gatagaaaat ctcgtcaata tataagacga
    30241 gttaaaaaga agaatccaga tgcaataata gccgttgtag gatgttattc tcaggtatct
    30301 ccggaagaaa ttttggatat agaagaagta aatttagtca tgggtacaaa tgatagaaga
    30361 aagattgttg aagaaattaa aaagataaat tcaagtaaga aagttagtac agttgatgac
    30421 ataatgaaag ttaaagcttt tgaagaaata gaaatcagcc aaactaatgg aaagactaga
    30481 gcatttatga aaatacaaga tggatgtgac agattttgta cttattgtat cattccttat
    30541 gcccgaggac gcgttagaag tagagatatt gatagtatag tcgatgaagt taaaaaattg
    30601 gctaataatg gctataaaga ggttgtatta acaggaatac atgttgcctc ttatggaaaa
    30661 gatttaaagg atagggatat taaacttctt gatgtaataa aacaaataaa ccagatagaa
    30721 aaaatagaaa gaattaggct tagttctgtt gaaccaattt tatttacaga tgaatttgta
    30781 aatgaagttt taaagatgga taaagtttgt cctcattacc atttatcact tcaaagtgga
    30841 tgtgatgaaa ctctaaaaag aatgaataga cgatacacaa ctttagagta caaaactatt
    30901 gtagatagat tgagaagtaa aatgccagat gtggcaataa ctacagatgt aatagtaggt
    30961 tttcctggag agacaaatga agagtttaaa aaaacgtacg agtttttaaa agaaatagag
    31021 ctttcacaaa tgcatatttt taaatattca ccaagaaaag gaactccagc tgcaactatg
    31081 gaaaatcaag ttgaccctca aatgaaacac tttagaagtg aacaactttt aaatttaagt
    31141 aaagtaaatt ttaataaatt tgcaactaaa tttatcggcc gtgagttgga tgttttattt
    31201 gaacaaaata tagaaggcaa taaatatgag ggattaactt caaattatat aagagttgtt
    31261 gttgaaagtg acaaaaatat acaaggtcag atattaaaag tgaaaataaa tgatgtaaaa
    31321 gatgaatatg tagaaggaat tttgctataa catgtagaaa ttataatatt tataagatag
    31381 gaggtggaaa gaatggattg tattttttgt aaaatagcga acggagaaat accttcaact
    31441 aaagtttatg aagatgatag agtcttagct tttaatgact tgaacccagt tgctccatat
    31501 catatattag ttgtacctaa aaaacattat gatagtttaa ttgatattcc tgataaagag
    31561 atggacattg tgtcacatat tcatgttgtt attaataaaa tagctaaaga gaaaggtttt
    31621 gaccaaactg gattcagagt cataaataat tgtggaagtg atggagggca agaagttaaa
    31681 catttgcact atcatatttt agctggtaaa aagcttccta attacgaagc gggacaaaac
    31741 taaactaaat tattgaaaaa ttgagttcct tcttgataaa aatacttgat aaaagtaaaa
    31801 atttagttta taataaacaa agtgttaggt tgtaatgcat attatgcaaa aagaacatag
    31861 ttacagtccc agcataattg cgctattgga gggagggaaa aagaaatgtc agaagtaaga
    31921 gttagagaga atgaaacatt agacagcgct ttaagaagat tcaagcgtca atgtgcaatg
    31981 tctggcatca tgtcagaagt gagaaaaaga gagcactatg ataagccaag cgttaagcgt
    32041 aagaaaaaag ctgaagcagc aagaagaaaa aacgctaaga aatagtagta aataagaata
    32101 aagaggtgaa ggggatgtcc cttaagcaaa agttacaaga ggatttgaaa tcttcgatga
    32161 aaaacaaaga tacagtgaga aaatctgtag taactttaat aagagcttct ataaagcagt
    32221 atgaggttga taatagggtc gagcttgatg aagatggaat tatcgatgta atagcaaaac
    32281 aattaaagca acgtagagat gcattagttg aatttgaaaa agctggaaga gaagacttaa
    32341 taaaagaaac agaaggtgaa attgaagttt taaaagagta cctacctcaa caattaagcg
    32401 aagaagagtt agaagaaatt gtaaaatcta ctatatccga agtaggggca acttctatga
    32461 aggatatggg aaaaataatg tcagttatcc aaccaaaagt taaaggaaga gctgacggaa
    32521 aacttataaa taagttggta aaacaaaact tacaatagat tgatatagcc tagagagaaa
    32581 tctctaggct ttttatagtt tttgggaata acgagtcata tttgagcata tctataatca
    32641 aagaaaattt tgaaagaagg ggaaaaattt gattatatca gtaaaagaga ttaggaattt
    32701 tttgataaac atatttatac cactaataat aggttactta agtagcatct taacaatgat
    32761 tatcagtgga acagatattt caacctatta tttacaactc acaaagccaa gctttgcacc
    32821 accagctttt atctttccta tagtttggac tatattgtac atattgatgg gtatatcttc
    32881 atacctaata ttaagaaagg gttacaactt acctaaagta agagatgcaa ttttttatta
    32941 tggattacaa cttgtattaa actttatttg gagtatacta ttttttggat ttggacttag
    33001 atttacagct ttgatagata taataataat gattttggtt tctataataa tgatttcgaa
    33061 gttttctaaa atagataaga gatctggata cataaatttg atttatttaa tgtggcttgt
    33121 ttatgcagga tttttgaact attttatatg gtttattaat aaatagaatg taaagatttt
    33181 gtaaattacc ctgtactttt aataatatca taacaaacga aaaataaata gactattaaa
    33241 aataatcatt ttcatataca ataatattaa tttaaataca ataaatttat aaaaattgta
    33301 tttaaagatt aacatattaa agtattagaa ttggaaaggc ttgaagggag aggtttttat
    33361 gcaaataata gtatctggga gacaaatgaa attaactgac ggaataaaag gatacgtaga
    33421 tggaaaatta agtaggttag aaaaatacct tgatcctgaa tcagaagtga aagtaacagt
    33481 aagtgcgaaa aaggatagac aaaaagtgga ggttacaata attcctatta acggtcaaat
    33541 aataagagca gaagatgtag aagatgactt atatgcagca attgatattg tttgtgacaa
    33601 attaagtaga caagttgtca aatataaaac taaagttaaa gacaaagttc aaaataataa
    33661 gagcataaga tttgaaaatc ttgactttat agataatagc agtgaatttg atgattatga
    33721 ttatgatgat gaagaagatg aaaatatagt aatagaaaga agaaagaaat ttaatgtaaa
    33781 acctatgagt tctgaggagg cgatacttca aatggaacta gtaggacaca atttctatat
    33841 gtttagaaac caagataatt ttgaaataaa catagtgtat aagcgtaaag ctggtggata
    33901 tggtttaata gaacaagatt aataaaaatt gtatacgttt agattttata taagaaaaaa
    33961 taaaaaggta atcatgttga ttttttatca atatgattac ctttttcttg tttaaataat
    34021 atattagata ttaggtattt attatataaa aattttaaaa ctaatctgtt acaacatcaa
    34081 taaagtgcat aaatacctat ttcaagcata aaattaatta agggggtaat gcttatgtta
    34141 gaaatatcca ctgatttaca agtaaatcaa ccagttatta ctgttacaag taatacgttt
    34201 attagta
//
LOCUS       DAEHWO010000040        33958 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEHWO010000040 DAEHWO010000000
VERSION     DAEHWO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33958
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.040"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            43..507
                     /gene="bcp"
                     /locus_tag="KNP54_002240"
     CDS             43..507
                     /gene="bcp"
                     /locus_tag="KNP54_002240"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBF0893138.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            517..1260
                     /gene="yaaA"
                     /locus_tag="KNP54_002241"
     CDS             517..1260
                     /gene="yaaA"
                     /locus_tag="KNP54_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBF0893139.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            1388..4045
                     /locus_tag="KNP54_002242"
     CDS             1388..4045
                     /locus_tag="KNP54_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBF0893140.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLVTIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      4099..4201
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            4311..5576
                     /locus_tag="KNP54_002243"
     CDS             4311..5576
                     /locus_tag="KNP54_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBF0893141.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            5606..6496
                     /gene="metA"
                     /locus_tag="KNP54_002244"
     CDS             5606..6496
                     /gene="metA"
                     /locus_tag="KNP54_002244"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBF0893142.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            6987..7430
                     /locus_tag="KNP54_002245"
     CDS             6987..7430
                     /locus_tag="KNP54_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0893143.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            7461..9278
                     /gene="ftsH"
                     /locus_tag="KNP54_002246"
     CDS             7461..9278
                     /gene="ftsH"
                     /locus_tag="KNP54_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBF0893144.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            9456..12158
                     /locus_tag="KNP54_002247"
     CDS             9456..12158
                     /locus_tag="KNP54_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBF0893145.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            12192..12890
                     /locus_tag="KNP54_002248"
     CDS             12192..12890
                     /locus_tag="KNP54_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893146.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            13247..14203
                     /locus_tag="KNP54_002249"
     CDS             13247..14203
                     /locus_tag="KNP54_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBF0893147.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            14380..14535
                     /locus_tag="KNP54_002250"
     CDS             14380..14535
                     /locus_tag="KNP54_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893148.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            14665..15678
                     /gene="aroF"
                     /locus_tag="KNP54_002251"
     CDS             14665..15678
                     /gene="aroF"
                     /locus_tag="KNP54_002251"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBF0893149.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            15700..16764
                     /locus_tag="KNP54_002252"
     CDS             15700..16764
                     /locus_tag="KNP54_002252"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBF0893150.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            16764..18077
                     /gene="aroA"
                     /locus_tag="KNP54_002253"
     CDS             16764..18077
                     /gene="aroA"
                     /locus_tag="KNP54_002253"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBF0893151.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLTFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            18055..19134
                     /gene="aroC"
                     /locus_tag="KNP54_002254"
     CDS             18055..19134
                     /gene="aroC"
                     /locus_tag="KNP54_002254"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBF0893152.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            19137..20333
                     /gene="pheA"
                     /locus_tag="KNP54_002255"
     CDS             19137..20333
                     /gene="pheA"
                     /locus_tag="KNP54_002255"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBF0893153.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNRYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSKFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            20380..21189
                     /gene="aroE"
                     /locus_tag="KNP54_002256"
     CDS             20380..21189
                     /gene="aroE"
                     /locus_tag="KNP54_002256"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBF0893154.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            21201..21734
                     /locus_tag="KNP54_002257"
     CDS             21201..21734
                     /locus_tag="KNP54_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBF0893155.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            21755..22594
                     /locus_tag="KNP54_002258"
     CDS             21755..22594
                     /locus_tag="KNP54_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBF0893156.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            22862..24343
                     /locus_tag="KNP54_002259"
     CDS             22862..24343
                     /locus_tag="KNP54_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBF0893157.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            24376..27810
                     /locus_tag="KNP54_002260"
     CDS             24376..27810
                     /locus_tag="KNP54_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBF0893158.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDKKKALESIQHQLNTKGIAVYQHRIRRRNGNIIWVSIKGRLIVDDGIEKGIWILNDI
                     TDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNVP
                     YSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDED
                     GNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESWQ
                     KPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRRM
                     NQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYNK
                     GTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPIF
                     RKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGIS
                     FVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADKC
                     EKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDRP
                     CNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            27828..28574
                     /locus_tag="KNP54_002261"
     CDS             27828..28574
                     /locus_tag="KNP54_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBF0893159.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQGKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(28523..28831)
                     /locus_tag="KNP54_002262"
     CDS             complement(28523..28831)
                     /locus_tag="KNP54_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBF0893160.1"
                     /translation="MNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            29635..33777
                     /locus_tag="KNP54_002263"
     CDS             29635..33777
                     /locus_tag="KNP54_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBF0893161.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTSPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIVNPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSTTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NISTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNI
                     AEITSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDF
                     WC"
BASE COUNT        13645 a         3774 c         5853 g        10686 t
ORIGIN      
        1 catagtataa aattattaat aaaaacaaaa ggagagatat ttatgttgag tataggaaca
       61 aaagcaccag aatttacact agaagataaa gatggaaata aggtaagtat gtcagatttt
      121 aaaggcaaaa aagtagtagt atatttttat cctaaagata atacaccagg atgtacacgt
      181 caagcttgtg cttttagaaa tgcatatgat ggatttaaaa aggaagatat acaagttatt
      241 gggataagta aagatagtat aaaatcacat caaaaatttg cagaaaagca tgaacttcct
      301 tttattttac tttctgaccc tgacttagtt gctataaaag cttttgatgt atggaaagag
      361 aaaaaaatgt atggaaaaac tgcattggga gttgtacgtg cgacatatat tatagatgaa
      421 aatggaatta ttgaaaaagt ctttgaaaaa gcaaaaccag acacaaatgc acaagagatt
      481 cttgaatatt tggaaaaaca ggagtaataa gaatttatga ttataatgtt atcaccagct
      541 aaaaatatga agaatataga agtatttgat agagatttga gtttgccttg ctttatagat
      601 aacacaaaag aaatagtgga aaatataaag acatttggta tagaagattt taaaaataaa
      661 atgaaaatta atgaaaaatt agctgtatta aataaaaata gatttgaaag cattaaattt
      721 gatagattag gaaaccctgc aatcttaact tatgatggaa tacaatataa aaatatagaa
      781 gcagaaaatt ttacaaggaa agatgaagag tttgcaaata gctgtattcg aatcataagt
      841 ggattgtatg gtgttgtaaa accatatgat agtatatatg aatatagatt agaaatgcag
      901 acaaaattac aagtaggtga gtttaagaat ttatacgaat attggggaaa tcgtatatat
      961 aaagaactaa tcaaagaaaa aacagctatc gttaatcttt catcaaatga atacagcaaa
     1021 tccatagaaa aatttattaa agatagtgat acatatatta catgtacttt taaagtaaat
     1081 aaaaatggca tattgaaagt ggaatctaca caagcaaaga aagctagagg tatgatgaca
     1141 aaatacattg taaaaaatag gataagagat attgaagaac tgaaaaagtt tgatttagaa
     1201 ggttataagt ataaagaaaa cttatctaac aatagtgaat acatatttgt aaaagagtag
     1261 aagttttgtt aaatattaaa tggcattgtt aaatttaggt aaaatatact tagtgtgtat
     1321 tgaattgaac ttgattttaa aatataatta ttcttaaatt aaaaaaagaa aggagtggtc
     1381 ttccaaaatg gaaaatcaca aacagatgcc ttggcattca agagcaacgc atgaaatttt
     1441 agaaagtcta gattcatcag aggaggggct caccgatacc gaggcggaaa aacggcttaa
     1501 agagaatggc ttaaatgaac ttagaaaaaa accacctaga acaactttac aaatgctttg
     1561 gagtcaaatt acagatgcta tggttatgat actaatagga gcagcaatat tatctttgat
     1621 atttggcgaa tttacagaag cttttgtaat actaataatt gtaacagtaa atgcagttat
     1681 tggaattgtt caagagaaaa aagcagaatc atcattagaa gcattaaaaa atatgaattc
     1741 acctacagct cgtgttatgc gtgatggtga agaaaatgtt attccagcaa gtaatcttgt
     1801 agtaggagat attgtttttt tagaagatgg agctatggtt ccagcagacc ttcgtttaat
     1861 agaaacatca agtttaaaaa ttcaagaggc ttctttaaca ggagaatctg ttccatcaga
     1921 aaaagatgca gatacaatct tacctaaaga atgtgtatta ggagaccgta gcaatatggc
     1981 gtatacatct tcaatagtca catatggtag aggtgtaggt gttgtagtag caactggtat
     2041 ggatacagaa gtgggtaaca tagcacatct tttagattca caagatgatt ttgatactcc
     2101 tataaaacgt aaacttaata ctgttggaaa gacattaagt gtcataggta ttattgtatg
     2161 cgttgttata tttgcaatag gtgcatttta tcagagacct ctcttgccaa tgtttatgat
     2221 tgcaatttcc cttgccatat caattattcc agagggatta cctgcaacag ctactattgt
     2281 aatggcttta ggcgtacagc gtatggctaa aagaaatgct ttaattagaa aattacctgc
     2341 tgttgaaaca ttaggaggag ctacagtaat atgttgtgat aaaactggta cattaacctt
     2401 aaataaaatg actgttacac atattgctgt caatggagat tttgaatctg gaaaagtgac
     2461 atcaatagat actgcatctg aaaaacatcc attagtgtat aaagagattg tttatgctgg
     2521 tgcactttgt aatgatgcat gtattaatcc agataaaaca gatgaaatat taggtgaccc
     2581 aacagagggc gcattaattt ttatggccaa aaaatttgga atagatcaag aagctcttga
     2641 agaagaatat ccacgtgtat ttgaacagcc ttttgattca gatagaaaat gtatgacaac
     2701 tgttcataat atagatgaaa agattattgc ttatactaaa ggagcagtag acgaaattct
     2761 tgacctatgt actaaaatat taacttcaaa aggtgaaaga aacattactg aagtggataa
     2821 aaagaatata cacgaattat gtcttaacat gtctaaagat gcattgcgtg tacttggttt
     2881 tgctaagcgt gagatttcat ctataccaaa agaagatagt gaaaatatag aatatgattt
     2941 aacatttata ggtatggttg gtatgattga cccaccaaga actgaggtaa ttgatgcagt
     3001 aagtacttgt aaagaagcag gtataagaac cataatgata acaggtgacc ataaagttac
     3061 tgccacaaca atcgctcatg agttaggaat atggagtgaa gaaaatactg tgatatctgg
     3121 tgatgaactt gataatttga gtgatgatga actagatgaa gctgttaaaa atactacagt
     3181 atttgctcgt gtatccccat ttgataaact tagaattata caatctctaa aaagaattgg
     3241 agaagtacca gcaatgactg gggatggtgt aaatgactct cctgccttaa agtctgctga
     3301 tattggtata gccatgggta taagtggtac agatgttgca aaagattctt ctgacatgat
     3361 tttaatggac gatagtttta caacaattgc ttatgcaata aaagaaggta gacgtgtata
     3421 tagaaacata caaaaagtta tacaattttt gcttgttggt aatatagcag agatacttac
     3481 gttgtttgta gcaatattat taaattggga tactccgctt cttgctgttc atattctatg
     3541 ggtaaacctt gcaactgcta cgcttccagc ccttgctctt ggagttgacc caccaagcag
     3601 aaatataatg aagcaccagc cagtgaaatc aaccactttg tttgaaaaaa atcttataca
     3661 aagagttgtt acccaaggta tatttgtggc aataatgact attttagcat ataaaattgg
     3721 tcttaatata gaaaatcatt ctgtaggtca aacaatggca ttttgtgtat tagcattttc
     3781 acagatgtta cgagcattta gtcagcgttc aaatacagat tcaatgttta atagaaataa
     3841 tggtaaaaat ccatttcttt taatctcatt tttaacttct gcatttttaa tagcagtaat
     3901 actatttgta cctgttttta gaaatgcttt taacttaaca gttttaaata acttagagtg
     3961 gcttgtaacg attgttttag ccataatgtc tgtaattcaa gtagaggttg ggaaaattat
     4021 taaaagaaaa aaattaaaaa aatagttgac aaaattagga aaaatatata agatataaaa
     4081 catagaaaaa ttaaataaat cttatccaga gaggtggagg gactggccct atgaaacccg
     4141 gcaaccagta tatttatata cattggtgct aaatcctgcg gcgaaagctg agagatgagt
     4201 ataattaagc ttatacagag cctgagttat atactcaggc tttatttatt ttaactctca
     4261 tctggtaaat agtttaattt tttttactaa aatctaaggg ggatacaaga atgtataata
     4321 aagaaacaat atgtgtgcaa ggaaattata aaccaggtaa tggagaacca agagtactac
     4381 ctttatatca aagtacaact tttaaatata gcagtataga ccaacttgct gaattatttg
     4441 atttaaaagt tgatggacat atatattcaa gaataagcaa tcctactatt caagcttttg
     4501 aagaaaaaat aagtttacta gagggtggag tatcttctgt agctgtatca tcagggcaat
     4561 ctgcaaatat gttggcagtt ttaaatatat gtaaatcagg agatagtata ctttgttctt
     4621 caaaagtata tggaggaaca ttcaatttac taggacctag tcttaaaaaa tttggtatag
     4681 atttaatatc gtttgactta gattcaagtg aagatgagat agtagaactt gcaaaggaaa
     4741 atactaaggt tgtgtttgca gaaacacttg caaatccaac tcttgaagtc atagattttg
     4801 aaaaaatagc aaatgtagct aagagaatta atgttccatt tattgttgat aattcattag
     4861 catctccagt gctttgtaac cctttaaagt atggagcaaa tatagttact cattctacca
     4921 caaaatattt agatgggcat gcttcaagtg ttggaggaat tatagtggat ggtggaaact
     4981 ttaactggga taatggaaaa tttccagaat tagttgagcc agacccaaca tatcatggta
     5041 taagctatac tcaaaaattt ggaaatgccg catatgcaac taaagcaaga gttcagttgc
     5101 ttagagacta tggaaattgt ttaagcccat tcaatgcgta tcttactaat ttaaatgttg
     5161 aaacactaca tcttagaatg gagagacata gtgaaaatgc acttaaaata gctagatttt
     5221 tagaaaaaca tgaaaatgta gattggatta attacccagg acttgaagat aacaagtatt
     5281 atgagaatgc caaaaagtat ttatcaagag gatgtagtgg tgttttatca tttggagtaa
     5341 gaggtgggtt agaaaatgcc aaaaaatttg tggaaaaatt acagatagca tctttggtta
     5401 cacatgtttc agatgtaaga acttgtgtta tacatccagc ttcaactact catagacaat
     5461 taacagaaga acaattaatt gcatctggag tattgccttc actaataaga ttatctgttg
     5521 gaatagaaaa tgtagaggat ttaatagctg atttaaatca agctttaaat ttctaatatt
     5581 ctaagagaaa gagaagtgaa aagatatggc tttaatacta ccaaagggat tacctgttat
     5641 taataaatta ttagatgaag gaatagatgt aatttataaa gaagatttta aaaaggaatt
     5701 aaagtatgaa gaaaacatag acactaagat agctatacta aatctaatgc ctataaagat
     5761 agatacagaa ttagatttac taagaaggat agataaaaca ggattcaacg tgtctgtgga
     5821 atttattaaa atttcaacaa gagaaagtaa aagaagttgt aatgaatatg ttaaagaatt
     5881 ttataaaaca tttgatgaag ccaaaggaga gtattttgat ggctttataa taacaggagc
     5941 tccagttgaa caaatggagt ttgaagaagt tgattattgg aatgaactag aagaaattat
     6001 ggattattct aagagaaaaa ctaaatctac attatatata tgttgggcag ctcaagcaag
     6061 tctttacaaa tactacaatg taaaaaaact tccactaagt caaaaatgtt ttggagtatt
     6121 taagcataag gtagataaag atagtaaaat agtagatgga tttgaaaatg aattttttgc
     6181 tccacattca agacatacta ctgtaaatat tgaagctttg aaagagaata aagagttgag
     6241 cattgtgagt cattctaaag aagctggtcc ctatataatt acaaattcaa gagatgtgtt
     6301 cgtaatgggt catagcgagt atgacaaata cactcttgat aaagaatata agagggatat
     6361 aaataaagga gataaaatat ctatacctca aaattactat attaatgatg acccttcaga
     6421 agagccaact gtaaaatgga aaaaacattc agaattgttg tttagaaatt ggataaaaaa
     6481 ctatttgata caataaattt taagagtata taaatgttaa ctaaaaaaat atagaaattt
     6541 ataggtataa agttaatctt aatgatactt tataccttat ttttttaaaa tttgacctta
     6601 taatagtagt tttatatttt aagaaaatca ctttaggtgt atgtagatag aggtggcttt
     6661 aattttatat atggtgcgat aatgggagac taaaccttta tagtatcaat aaatttgtat
     6721 tttaactttt aaaagagatt aaaaagggag aaatcagtgt aaaatatata tatagatttt
     6781 ttattaaatt ttattaaaaa tatcctgtat aaaattaaat atcaataaga taacaaaatt
     6841 tcaattgaag ttacaatatt gtaattgaca ataaatactt aatactataa tatttaatac
     6901 attaaacatt atagtgttaa gtatttattt acagtatgca cttcagccta aatttgaaat
     6961 aaagtatttt cgtagggagc gtttgtatgg atgagatgag ttttaagaaa gagctactag
     7021 agttgactag agatataaat atgaaattta caactttatt aagtgatttt tatcagccac
     7081 ttggtattac agcagtgcaa gctttgattt tatctgagtt atgtgaacat ggagagaaaa
     7141 aaataagcga tttagggaag aacttaaaca tgacaaatag taatgtatca gtaatctgtc
     7201 aaaggcttga aaaaaatggc tttttaaatc gcataagaga tatagaagac caacgaattg
     7261 taaaagtaaa agttacaaat aaatcattgg atatacaaga acatatttca agtagtattt
     7321 ttgatagtta ttttgaaaat atgaccagtg aaaaattgca agatatggaa gatataatag
     7381 aaggtttaga gaaattaaat aaacttttaa cttacattga ttgcaaataa cataaaaata
     7441 atttaaagga gaataaaatt atggatgaac ataaacccca aaaaaggtca gcactctatt
     7501 attatacagt tataataata gtagtaatgt ttttaaatgc tttaatattt ccaagtttaa
     7561 tggataaaaa aatggttgag attgactatg gaaagtttct cacaatgttg gatacaggaa
     7621 aggttaaatc tgttgagata gaaaataata gaatagcaat aaatccatct agtagcaagg
     7681 ataagaatat atacataact ggtagaatgg atgacccaga attggtagat agactaaaaa
     7741 atgcaaaagt agaatttact aaggttattc ctaaggaaaa ttcacctctt ttaagtattt
     7801 tacttacatg gataatacct ataggtattc ttatgctatt tggtaactta atgatgaagt
     7861 ctatgcaaaa gcgaatgggt ggtaatgcta tgcaatttgg aaaaagcaac gccaaaatgt
     7921 atgtatctgc tcaaagtgga aaaagattta atgatgtagc tggtcaagat gaggcaaaag
     7981 aagctttaac tgaaatagta gatttcttac acaatccaga aaagtataaa aagataggag
     8041 cacaaatgcc taaaggagca cttttagtag gacctccagg tacaggaaaa acactccttg
     8101 caaaagctgt agcaggtgaa gcaaatgtac catttttctc aatatctggt tctgagtttg
     8161 ttgagatgtt tgtaggaatg ggagcttcta ggattcgtga tttatttaaa caagcaaaag
     8221 aaaaagctcc atgtatagtg tttatagatg agattgatac tattggtaaa aagcgtgata
     8281 atggaagtgg attaggtgga aatgatgaac gtgaacaaac tttaaatcag ttgttaagtg
     8341 agatggatgg ttttgatggt ggaattggag tagtaatact tgctgctaca aatagacctg
     8401 acagtcttga caaagcatta cttcgtccag gaagatttga tagacgtata ccagttgaac
     8461 ttccagacct tggaggacgt gaagctatat taaaggtaca tgctcaaaat gtaaatgtaa
     8521 gctcagatat agattataat gcaattgcaa ggtctacatc aggagcatca ggtgcagaac
     8581 ttgcaaatat tgtaaacgaa gcagcacttt tagcagttaa gtctggcaga gatatagtag
     8641 aacaacagga ttttgatgaa tctgttgaaa ctgtaattgc tgggtatcaa cgtaaaggag
     8701 ctgtaatttc agataaggaa aagaaaatta tagcatatca tgaaataggt catgcacttg
     8761 ttgctgctat gcaaaaacat tctgcacctg tccataagat tactataata cctagaactt
     8821 caggagcatt gggatatact atgcaagttg ctgaagatga gagtgtactt atgtctaaag
     8881 aagaagcaat tgataaaata actactttta caggtggtcg tgctgctgaa gaggttatct
     8941 ttaacacttg tacatcagga gcatcaaatg atatagaaca agctactaaa attgcaagag
     9001 ctatggttac tcgccttggt atgagtgaag agtttgatat ggtcgctctt gaaactgtaa
     9061 gcaatcaata tttaggagga gatacttctc ttgcttgttc ttccgacact gctgctaaaa
     9121 tagatgaaga ggtatttaaa atagtaaagg cttgtcacaa aaatgcaatt gaaatcttag
     9181 aaaataatat tgataaattg catgaacttg ctaattattt attagaaaaa gaaactatta
     9241 caggtgatga gtttatggaa atacttaact taaactaaaa tgattataca caagataaaa
     9301 atgcctattg ttaggcattt ttattttaca actaaatttt ttaaatttat atttaaatct
     9361 ttacataatc ttaatcatta aaaatacatc ttaactacaa ttttatatcg gaattgatat
     9421 tataatagta atgaatggtg taaggaggtt ttttaatgga tagacctaat cctgatattc
     9481 tattagaaaa aattaaaaat gaagaagaaa aactaagtag aggtcaatta aaaatattct
     9541 ttggttatgc agctggagta ggaaaaacct actctatgtt ggaatctgca caaaatttaa
     9601 aaaaagtggg tgtagatgta gtagttggat atattgaacc acacactaga ccagaaacat
     9661 tggctttact tgatggcttg gaaattcttc ctgtaaagga gatagaatat aaatctataa
     9721 aactaaaaga atttgattta gatgctgctt tagcaagaaa accagaagtt atattagtag
     9781 atgaatttgc ccattctaat gttgctgggt taaggcatac aaaaagatgg caagatatag
     9841 aagaattgct gttagcaggc ataaatgtct acactactgt aaatgtacaa catttagaaa
     9901 gtctaaatga cattgttgag ataattacaa acgtatcagt taaagagact ataccagata
     9961 agtttttgga tacaaataca cagttagaac ttatagatgt tgaacctgat gtacttcttg
    10021 aaaggttcaa tgaaggtaag atatataaga aagaacaagc tactagagca aaaaataatt
    10081 tttttataaa agataacctg gttgcactta gagaaattgc acttagaaaa acagcagaga
    10141 gagttaataa agaagttcaa atgaccagac tatcaaaggg tgatgtaact gtaataccta
    10201 catcagatac acttcttgca tgtataagtc catctccatc ttcagcaaaa gttattagaa
    10261 ctgcatccag aatatcagac agtacatttg caaaatggat agctttatat gttgaaactc
    10321 caaacacagc aagacttcca tttgatgaac aaaaacaact acaaaataac ctaaaattag
    10381 ctaagaaatt aggtggagaa ataattgttt tacatggtga aaatataata gagcaaatac
    10441 ttagaattgc aaagctgaga aatgtaacaa aaattgtaat aggtagaaat cattcaagta
    10501 ataaaagatt tagtaaaaga tttaaaaaag atatagttga caaattaatt gatgaagttg
    10561 attatataga tatacatata attccatata aatttgcctc agatgttaaa tacaaaccta
    10621 aaaaggataa atcatcaata aaatctaaat ttaaaattag caaagttgat tttataaaac
    10681 ttatatttat tactttgatg ataagtattt tagcatatgc agtacaaagc atgggattta
    10741 taagagaaaa tatattgtta atatatatgt tgggtgtagt tttagtttct atgtggacta
    10801 aagggtatag tacaggtata ataagttctg tatttaatat agttctttta aattattttt
    10861 ttacagcacc attatataca ttatctatag cagattcaaa ctatatagta acactggttg
    10921 tattctcaat agtaggtata ataactagca ctcttacgtc taagatacag catgaagcag
    10981 aaactgctgc taaaagagaa gaaaatacaa aaatgatata tcaaataatt aagggatttt
    11041 taagattatc aaataaagat gatatagtaa acaaaggtat agaacttttg tctcttagct
    11101 taagtagaga tgtaatttgt tatttaaatg tagataagca taataaatca aagctttaca
    11161 aaaaaaatac taataataag gataaaaatg atttggatag tgaagatgaa aaagctgttg
    11221 caagttgggt tttatccaat tcaacagtag caggaaatga cacggataca cttcctggtt
    11281 caaagggata ctatatacca attgtaggaa tgaatttaac tttaggagta gtgggaatat
    11341 catgtattga ttcaaaattg gatacagaag atataagctt aattgaaaca ataattgctc
    11401 aaatggcaat agcgcttgat agagaaatct tgtcagaagc taaagaaaat accaatcttg
    11461 agattgaaag ggaaagatta agaagtaatc ttttaagagc agtttcgcat gaccttagaa
    11521 ctccactagc aggaatatct ggtgcagtaa gtacaattat aaaaaacaag ggtactatag
    11581 gtcaagatat aatagatgaa ttacttagtg gtgtatatga agatactcag tggttaataa
    11641 gacttgttga aaatttactt agtatgacca agatagatga agggaaattg gaagttaaaa
    11701 aacattctga actggttgag gaaattatat cagaagcgtt acaaaaaata aaaaaaagaa
    11761 ttgaaaatgc acttatagat attaatatac cagaacagat attatttgtt cctatggatg
    11821 caaaattaat agaacaagtt ttaattaatt taatagataa ttctttgaaa tattcaaagg
    11881 aagattgtaa gatagagata aatgtatatg agaaagatga ttatgtttgg tttgaagtat
    11941 ctgataatgg tcctggtata tcaaaggaac ttaaaaagca tatctttgac agatttttta
    12001 ctggagaaga aggagctaaa gattccagaa agggtgttgg acttggatta tcaatttgta
    12061 aatctataat tcaagctcat aaaggtgaaa ttatggtaga aaacaataaa gataagggtt
    12121 caacttttaa gtttagtttg cctaaggaaa atgaatagtt ttaaatttta aaattagttt
    12181 tggaggaaga aatgagtaaa aaacttatat tgttagtaga ggatgataag acaataagaa
    12241 aatttatatc tactgcactt ttaacacagg attatgatgt caaggaggct ataactggaa
    12301 aagaaggtat atctatagct gtctcatatt ctccagatgt tgttctttta gatttaggct
    12361 tagaagatat ggatggaata gaggtaataa aagctatcag acaattttca aatataccaa
    12421 taattgtagt ttcagctaga gagcaagata gagacaaggt agaagtattt gatgcagggg
    12481 cagatgatta cttaacaaaa ccattctcca tagtagagtt attagcaaga gtaagagtag
    12541 catttagaca ttcacaagta gaagctcaac aaaaagatga tgttaaatct acgtttgaag
    12601 tagataaatt attgattgat tttgataaaa gaaaagttat tgttgatgat gttgaagtcc
    12661 atttgacacc tattgaatat aatattcttt cattacttgc aaagtatcat ggaaaagtgc
    12721 ttactcataa ttttataata aaagaaatat ggggtagtgt tatagggaat gagactaagt
    12781 ctttaagggt ctttatggca acgttaagac gaaaaataga aaaacaacct gcaaacccaa
    12841 gatatataat tacagaagtt ggtgtaggat acagattaaa tgatgaatag ttgtaatata
    12901 ttaattatta gattatgtgc ttattaatat atattaaaat tatatagttt agttaaaata
    12961 agaatgaagt gtatgtgctt gttgtcagtt tagcacatgc attttatttt ttagcttttt
    13021 tagtatcaat aattttttag tatcaataat atgaaatatg ttttaaaata agtatatagt
    13081 gtaatatgta ataaaaactt tggttaaata ataaatgtat ttaacactta ccttataata
    13141 aatttaatat aaatattaaa taataattat taaaatagtg taaaataatt acagtaagga
    13201 ttataaaaaa tttttagaat gtaaattgaa atttaggagt agatgtatgt atatactgaa
    13261 tttaaataca agagagacta ttgaagattt tagagataaa ttttatgtag cagaaaattc
    13321 ttatcttata ttaagtgctc caaaaaattt aaaattgctt aaggaaactt tggatataga
    13381 tgaaataact tttaatgatt gtcttaaatt tgatgaaata accaaacttg atttatttga
    13441 taattacgat tttttaagcc taaatacatt tgaactaaga gatggagaag ctgttataga
    13501 agaggtaaat atgtatttat cagataattt tatattggtt gtagtgaatg aagaacactt
    13561 tttatttgaa tttgtaaaaa atattatttt gaagaactct caacttgaaa aaaatccagt
    13621 tattaatcta tttaagataa actacttgat tcttagagaa gttataaaaa atggttttga
    13681 gtctttggaa aaagttgaag agttaattct tcaaatagaa gatgaaatga tggacaacat
    13741 taataagaat catgtatcta gaataagtga tgtaagagga ttaacaagaa ttatagttaa
    13801 gaatactaga cctcttttgt atattgggga tagaatagtt aaggaaaata taagatattt
    13861 aaaatattca aatgtaaaaa aatataattt agaaaatttt caaggtatag attttggaat
    13921 tgacaaatta tacaatttcg cattgtcaac acgagagtta gcagataaat tattagatat
    13981 ttattcttcc agagtaggtg agaaaacaaa taacttaatt acaaaattaa ccttgttaac
    14041 agccatatca gcaccactta caattataac tggtatatat ggaatgaact ttagatatat
    14101 gccagaatta aactggattt atggatatcc agcaacttta ttttttatgc tatgtataat
    14161 ttttgttgga attataatat ttaaaataaa aaaattattg taaattacag atgatgttta
    14221 attgatttta taaaaataca tcaattgaga agctgattta agtaaataaa aaaatatttt
    14281 aaattgaaaa tatttataga aaatattgac aattatattt tctttgttat aattattaaa
    14341 caagaagaat aataaattat aaaaatggag gataatacta tgaaaggaat attaaaagaa
    14401 ctaacagcaa aactttatag ctttttttac tttatgttct ggggctttta ttttagcgct
    14461 ggctatttct tttacaaaaa tatatgtact tcctttctgg tgaggcctta ttttagtgat
    14521 tttgagcata agtaaatttt ataaaaatga ttattttata tatttatata agatttagtg
    14581 cttgatagat tattttagag aactcattag tgagttctct tttttatttt aaatataaaa
    14641 ttataatatt gggaggtagt aaaaatgata gtagtattaa aaatgggagc agataaaaat
    14701 gaagttaaaa aattaattga ggctattggg agagaaggag tagaagttaa tcccatagat
    14761 ggaacagaat taactgtttt aggtttagtt ggagatacta gtaaaataga tgccaaaaga
    14821 atagaagcaa ataaggtagt tgaaaaagtt atgcatgtgg tagagccttt taaaaaggcc
    14881 aatagaaaat ttcatccaga accttcaatc ataaatgtta atggaatgga aattggttca
    14941 aagaaaattg ctatgatagc tgggccttgt tctgttgaaa cagaagacca aatagtatct
    15001 atagctaaag atgtgaaaaa atcaggtgca ggatttttga gaggtggagc attcaaacca
    15061 agaacatcac catacgcttt ccaaggattg aaatatgatg gattggattt attaaaaaaa
    15121 gcaaaagaaa aaacagggct tcctatagtt acagaaataa tgtcaacaca agatatagat
    15181 atatttgaag aaaatgtaga tgtaattcaa gttggagcta gaaacatgca aaactttgat
    15241 ttattaaaag aattaggtaa aacaaataaa acaatacttt taaaaagagg attatctgct
    15301 acaattgaag agtggctaat gtcagcagag tatataatgg ctggaggaaa tgaaaatgta
    15361 gttctttgtg aaagaggtat aagaactttt gaaacatata ctagaaatac tttggattta
    15421 agtgcaattt tagctgtgaa gaaacttagt catttaccag ttatagttga cccaagtcat
    15481 gcagcaggta aatcatggat ggttgactct ttatctaagg cagcaattgc agttggagca
    15541 gatggtctaa taatagaagt tcataatgac ccagcacatg cactttgtga tggaaaacaa
    15601 tcgattaagc caaatgaata tgatgaattg ataagtgaat taaagactat cgcatcagca
    15661 gttggtagag aaatataatc tataaaagga tggttaaacg tggaagaaaa actattagta
    15721 aatttaaaag aaaatagcta caatatattt attaaaaaaa atatactaaa gaatatagga
    15781 gaagaaataa aaaaaatata ttttggaaat aagattttta ttgtaactga tgaaaatata
    15841 gcaaaattat acttggataa agtaaaaaat aatttaagtg aatctggatt tgaaattaaa
    15901 tctttaatat taaaatctgg tgaagaaaca aaatcattta atactcttcc taaaatatac
    15961 gatagtttac ttgactttaa gttaactaga aaagatttga ttattacttt aggaggaggg
    16021 gtaataggtg atttaggtgg atttgcagca gcaacttttt taagaggtat aagttttatt
    16081 caaattccaa catctttatt agcacaagtt gatagttctg taggtggaaa agttggagtt
    16141 gaccttgaga gaggcaaaaa cttagtggga agcttttacc aaccaaaggc tgtgtttatc
    16201 gacccaaatg tattattatc acttccagaa aaattctata gagatggaat ggcagaagtt
    16261 ataaaatatg gatgtataaa agacaaaact tttttcaata aacttttaag tttaaaaaat
    16321 agagaagaag taatgcaaca tatagaatac attatacata aatgttgctt tattaaaaaa
    16381 actgtagttg aagctgatga aaaagacttt ggagatagaa tgcttctaaa ctttggccat
    16441 acattaggtc atgctattga gaaatactac aattttacag gttataccca tggagaagct
    16501 gttgccatag gaatgtataa gataacttta gaaagtgaaa agataggaat tacaaaaaaa
    16561 ggtacatcag aacttataaa atcaatttta atgaattata atttgcctta tgagattgaa
    16621 ttaagagata ataaatctat agtagatgct atatctcttg ataaaaaaaa tctaggtgat
    16681 acattaaaaa taatactttt aaaagatatt ggagagagta ttatatataa tactacttct
    16741 aaattttttc aggaggtaag ataatgggaa gtctaaaaat atatccaagt aaattatctg
    16801 gagatgtaaa aataccacca tcaaaaagta tggcacatag ggcagttatt tgttcatctc
    16861 taagcaatgg aaaaagtaga atttctaata tagatttttc tgatgatata atagctacta
    16921 taagagcaat gacatcatta ggagctatta tagaaaagaa agaagatatt ttagaaattt
    16981 cgggaatttt ttctaaagaa ggtattttaa atagagagaa tcagttgaat caacctaaat
    17041 tgacaataga ttgtaatgaa tcaggctcta cattgagatt tttagtacct atatctttaa
    17101 catttgatgg tgtaaaaagg tttataggta gaggtaatct tggaaaaaga ccacttgata
    17161 cctattatga gatatttgac agacagaata taaaatatag ttacaaagaa aatcagttag
    17221 atttgattat atcaggtaag cttaaaccag atgaatttag agtaaaagga aatataagtt
    17281 ctcagtttat cacaggttta ctgtttatat tgcctacgct agaaagtgat tcaaagataa
    17341 taattactac tgagctagaa tctaaaggat atttagattt aactctttca acgataaaag
    17401 attttggggt agaaattata aacaataact ataaagaatt tattataaaa ggaaatcaaa
    17461 cgtataaagc gagagattat aaagtagaag gagattattc tcaaggagca ttttatttat
    17521 cagcagatgc tataggagaa gatattagca tattagacct taaagaagat tctcttcaag
    17581 gggatagtga agtagttgaa attttatcta ggatgggaat ggaaatatta agagaaggca
    17641 acaaaataaa aggaataaca aatggtttaa atggtacttt gatagatgca tctcaatgcc
    17701 cagatataat acctgtatta tctgtagtag catccttaag tatagggagg actacaataa
    17761 ttaatgctgg taggcttaga attaaagaat gtgatagact tcatgcaata aatgttgagt
    17821 taagtaaact tggagcaaat atagaggaga aagaggatag tttgataatc gaaggagtaa
    17881 gcaagttaaa tggtggagta gaggtgtgga gtcacaaaga ccatagaatt gctatgacac
    17941 ttgcaattgc ttcttgtaga tgtgataaac caataatatt aaaagatttt gagtgtgtat
    18001 caaaatctta tccacatttt tttaaagatt ttaagatgtt aggaggtcga attgatgagt
    18061 ggaatatggg gaaataattt aaaagtatca atttttggag aatctcatgg aaatgctata
    18121 ggtataaata tagatggtct tccttcgggg attgaacttg accttgataa tattgataaa
    18181 gaaatgaaga gaagagcacc tggaaaaaat tctatatcta cttcaagaaa tgaaagtgat
    18241 ataccagaaa ttctaagtgg atattttaat ggaagaacta caggaacgcc attatgtgca
    18301 atcataagaa atagtgatac tcgttcaaaa gattatggag agcttaaaaa tttaatgaga
    18361 ccaggacatg cagatttcac aggtaatgtg agatattctg gatttaatga ctatagaggg
    18421 ggaggtcatt tttcaggtag gataacagct ccattagtat tttgtggggc tatatgtaaa
    18481 caaattttat cacaaaaagg aatagagata ggagcacaca taaaaaaaat taaaaatata
    18541 gaagatatga gttttgatta tgtaaatatt tcaaaacaac agttatcaaa tttgcaaact
    18601 ttggaactac ctttacttga tttatcaaag gaagaagcca tgaaaaatac gattatagat
    18661 gcaaaaaatc aaggagattc agttggtggt ataattgagt gtgcagtagt aggtattaat
    18721 gtagggcttg gaaatccatt ttttgactct gttgaatcta ctttatcaca tttattgttt
    18781 tctgttcctg ctgtaaaagg tgtagagttt ggtttaggtt ttgaacttgc agatatgtat
    18841 gggtctcaaa gtaatgatga aatgtattat gaaggaaatc aagttaagag caaaacaaat
    18901 aacaatggag gaattatagg agggattact actggaatgc caataatttt caaagtggca
    18961 attaagccaa ctccatcaat tagcagacaa caaaacacag ttaatataaa agataaaaag
    19021 gacgatattt tatatattaa aggtagacat gacccttgta tagttcaaag ggctatacct
    19081 gtaatagaag cagtaacagc cattggaatt tttgatttga tgaaaggacg ataataatgg
    19141 aggatttaac gagatataga aatgagattg acaatataga taaagagctt attcaattat
    19201 ttgaaaagag aatgaataca gttcttgaaa ttgccagaca taaaatgaaa aataacacta
    19261 ctatacttca aaaagataga gaagaaaaag tactaagtag agctgtagat aatttagata
    19321 ataaagcata ttcacaagaa acggtacagt tttttaattc tataatggaa attagtagag
    19381 gattacaaaa aagattgata gataatgatg gtgagcagaa aatcgagttt agtttagatt
    19441 catcaaataa gaaatttgat ttgtcaaatg taaatagata taagtcttta aaagatgaat
    19501 taaataaaaa aaatatccta gtaggatttc caggaaaatc aggttcattt acagaagaag
    19561 cactaaataa attcttcaac aaaaaaatat caaaaaaaca atttaaagaa tttgaagatg
    19621 ttttcatagc acttaaaaat aaagaaataa actatggaat aatccccata gaaaattcat
    19681 ctacaggagc tatctctgaa acttatgacc ttttgagaaa gtacggtttt tatatagttg
    19741 gagaagaatg tataaaaata gaccaaaatt taatagggat aaaagacaca aagcttgaag
    19801 atataaaaga aatatattct catccacaag gtataggaca atgtagtaaa tttttaaaac
    19861 aaaatagtac atggaaattg ataccattta ataacacagc aacaagtgca gaacttgtaa
    19921 gaaaacttca agataaaaca aaagcagcaa ttgcaagcaa aaaagctgca agtatttatg
    19981 gattagaaat aataagtcct tgtataaatg atattgcaaa caactataca agatttgtag
    20041 taatcagtaa tcaaatacac attgaagaag aatcaaacaa aatgagtgta gtattttctg
    20101 ttgaacatga agcaggaaaa ctttataaag tacttggata ctttgctaaa aataatataa
    20161 atatgacaaa aatagaatca agacctatga aaaatgcctc atggagatat ttcttttata
    20221 tagattttga gtgttctata tacaatgcta aagtgtacga tttattagaa ttgatagaac
    20281 ataatacagc atattttaaa tttatgggag tatataaaaa taaaactgaa tagataagat
    20341 aaatttttat ttaatttata attattagga ggtgtaagta tgaatttttt cggtctagta
    20401 ggtgaaaaac tctctcacag tgtttcacct caaatccaca agagagtatt cgagatattg
    20461 aatattgaaa gtgcttataa aaactttgaa atttcaaaag aagatatatc taagctagac
    20521 ggtgctataa aattattagg aatacaaggg gtaaatgtta ctgtaccata taaggagcgt
    20581 attatgaaat atcttgattt tatatcacca gaggcaaaac gtataggagc agttaataca
    20641 attttactta gagaaaatat gttatatggt tacaatacag attactttgg tcttgatagt
    20701 atgtttaaaa tggctaatat tgatgttcaa ggaaaagtag cagttatatt aggaactgga
    20761 ggtgcttcta aagctgctct tacatatttt attgattctg gtatagaaaa gctttatgtt
    20821 tcaactagaa aaaaggatga taaaaaatta ttaaatagta aagctatatt aatagattat
    20881 gaagaactta aacatataaa aggagatata atattaaatg ctacaccagt aggtatgtac
    20941 cctaatgtag gaatttcacc agtgtcaaaa tctattatac aaaattttga tatattaata
    21001 gatttaattt acaatcctgg agaaacagag tttttaagaa ttggtaatag tatgggtaaa
    21061 aaaacttgtg atggattata tatgctggtg gggcaagcaa taaaatctca ggaaatttgg
    21121 caagatacta aaatagataa tagtatttta gatgttatat ataatgaact aaaattagaa
    21181 tttttgtaag ggagattgtt atgataaata aaacaaaaga aaaattgata ttaataggta
    21241 tgccaggtag tggaaaaact acaattggta aacttttggc caaagaatat aattgtagtt
    21301 tctgtgatat ggatgattat ataattcaaa tatctcaaaa aagtatagca gagttgtttt
    21361 cagaaggaga agatatcttt aggaactatg agactcaagc atgtagagaa ctttctataa
    21421 gtgataaaac agtgatatct acaggtggag gtgtaataaa aaaggatgtt aatatggaaa
    21481 tactaaaaga aacaggtata ataattttta ttgatagacc tatacaaaag attttggaag
    21541 atataaatat taattcaaga ccattattaa aaaacggaaa agatagattg tataatcttt
    21601 ataatgagag aataaatctt tataaaaaat tttcagatat agagatttta aatgataaat
    21661 cattaaataa tgctgtatat aatattacaa atgcagtcag tgaaaatttt aaatttgact
    21721 ttaaagaaaa ataatctagg gggaaataaa aataatgaat attgttattg taggactagg
    21781 agttatagga ggctcttttg ctaaagcatt aaaaaaagct ggatatgaaa atgtatttgg
    21841 agtagatgta gatttagaaa ctttaaaaaa agcagaaaaa gcaaaaatca taaaaaaagg
    21901 atgtactaca ggtaaagagt tatttaaaaa agctgattta attatattat ctatatatcc
    21961 tagattagtt gtagattttc taaataataa taaaaacttt tttaaaaaag ggactataat
    22021 tactgatact acaggaataa aagaaacact tatcaatgat gtgttgcaaa ttattccaga
    22081 tgatatagat tttatatttg gacatccaat ggcaggtagg gaaaaaaagg gtattgattt
    22141 tgcaagtgaa caagttttta atggcgcaaa ttatataatt actccaactg gcagaaacaa
    22201 cataaaaaat ttagagttag ttgaaaattt aattttagag attggattta aaagagtaaa
    22261 aaagttaact tcacaaaaac atgatgagat tatagctttt acttctcagt tacctcatgt
    22321 tatggcagtt gctcttataa atagtgatga agaaggtaga gatacgggta aatttattgg
    22381 agatagttat agagatttaa ctagaattgc aaatatgaat gaagacttat ggagtgaact
    22441 ttttttagga aatagagata atttactaaa agttatagaa aactttgaat cagaagtaaa
    22501 tttagtaaaa gaagctatat ttaacaatga taaaaataaa ttaatagagt attttaaaaa
    22561 atcatcaata agaagagaag ctttagaaaa ataaatatta atatttaagc tatatataga
    22621 tgggtataaa tataagcgat agtgtattta attgtattaa taaatatgga ttcaatataa
    22681 ttaaatatgc tattgatata tttgtaccct taactattgt tatcttttaa atgataatga
    22741 tatttattta aatactcttt attaacaatt tataaaactt aattgtaaaa aatacttatt
    22801 aatagtaaaa taaagtgaat caattatatt ataattgcta aagagagtga ggtgtagcta
    22861 tttgaaaaaa aatagattaa tagcaaagaa tatatcaata gcatttatag tactattctt
    22921 ttttagtgta tttacatttt tttatgtagg taatattaat agagtgttag aatatgaaac
    22981 aaatgacata ataacagtta caattgctgg atggattata ctttcatttt tatttttagg
    23041 tattataatt tacatattat attcaaaagc aaatagtcaa aaaactatag aaaaagtagc
    23101 atatacggat tttgtaacag gttattccaa ctggagaaag tttgaattag atgttacaaa
    23161 tttattaaag aaaacatcac aaaataataa atatgcaatg gtcatattcg atattgataa
    23221 atttaaagca attaatgata tatatggcca taaaaaggga aatttaatat taaaagatat
    23281 tgcagatact ttaaatgaat tgactgatat caatgaaact tttgctcgtg taagtgctga
    23341 taatttcaat atattattaa catataacaa aaaagaggat ataataaata ttatcaaaaa
    23401 gattatggca aataatgaac ttgtaaactt atcttttgga atttatgaaa tcaaagataa
    23461 ggatttatct gtaagtgtat atagtgatag agcttcactt gcaaaatcat caataaaaaa
    23521 taatagtgat gtaaattttg cattttttaa tgacaaatta agagagaaat tattatttga
    23581 agataagata gaaaaagaaa tggaatatgc tcttgaaagt gggcaattcg taatgtattt
    23641 acaaccaaaa tacaatatta aattagataa attttgtgga agtgaagccc tagtcagatg
    23701 gcaatataca gaaaaagagg tcatatatcc aggtgatttt attcctatat ttgaaaaaaa
    23761 tggatttatt agaaagattg atatgtacat attagaacaa gcttgtaaag aaatccggtc
    23821 tttatttgat aaaggaattt cacctttacc tatatctgta aacttctcaa gagttgattt
    23881 ttttaaaaaa gattttattg aaaacatagt aaatatatgt gatagatata aaataccata
    23941 tagtttaata gaaattgaaa ttactgaatc tagtatgttt ggagatactg atactctatt
    24001 taatgttagt agaaacctac aggatattgg ctttatagtt gcaatggatg attttggctc
    24061 tggatattct tctgtaaata tgcttaaaaa tataccatta aatgtaataa aattagatag
    24121 aggatttttt gttgatgata aagatgttga taagagtcaa attgttataa aaagcatagt
    24181 ttctctcatt aagcaattag gaataagggt tgttgctgaa ggaattgaaa caagaagtca
    24241 aatagaaatg ttaaaaaaag caaattgtga tattgttcaa ggatattatt tttcaaaacc
    24301 attaccaatt aaagaatttg aaaaattagt ctataaaata tagtcagcga gtcttaaatg
    24361 ggaggtggtg attaagtgat aagagcaaaa tcgttaaaaa atgtactgag tattgtttta
    24421 atatttttat ttacaataat ttctttttct gattttgcat ttaaaactaa tgtccaggaa
    24481 gaagaaaata gtaaaattaa tttaagagaa atatccctac aaagttccaa tgctataaaa
    24541 ataaaattag atagttctct atcctttatt aaaagtgtgg caaatatggt ttcttatttt
    24601 aatactatag ataactcaaa aatagttcca ttattagcta atatatcaaa agaatctgac
    24661 tttcaaagaa tctctattgt atctcctgat ggaataagtc ataccagtga tggcaaaatt
    24721 atcaatgtgt caaagtatca gtattttaag aaagctatta aaggagaaag taatatatct
    24781 gaagttgtga aatctccaat tgatggaaaa gatacttttg ttatagctac tcctgtattt
    24841 aataagaata acaaaataat tggtgtttta tacggttctt actacaatga taaattagct
    24901 gaatttatag atataacaag ttttaatagt gaagggtaca tagatatatt tgaatctagt
    24961 ggtcaatttg ttttaaaatc ttcacataca aacaaactga ttaagtcaag tagtaacata
    25021 tatgatatat ttaaaaaagc ttcttttgat gatggttata gctataaaaa aatatatgaa
    25081 gatacaaaaa ataacaagag tggctttacc tcatatgaat acaaaggaga aaatcgttat
    25141 gctacttata cacccattgg tgtaaatgac tggtatgtaa tttctgtgat accacaatat
    25201 actgtaagaa gaaacattga taaaataaat caattagcat tttctcttat tttcaaggta
    25261 ttcttattgt ttattatgct tataatatat attatttata aaaacaataa atctcagaaa
    25321 gatatactaa aagctaacaa agaaatctca tctattacaa atagcattcc tggaggagta
    25381 caaaagtgta ccctgggtga aacatgcaat attaattttt taagtgatgg atttatagag
    25441 ttgtttggtt atacaagaga agaaataaaa acattgttta ataatgattt ttatagttta
    25501 atacataaag atgatgttga aagaataaaa aaagaaattt ttaaacaact ttacaaaaat
    25561 aaaactgttg aattagaata taggattata acaaaaaatg gtaatacagt atgggtttta
    25621 gataaagggg agcttataac agaacctgat ggaaaagaat atttttgttg tgtaactgta
    25681 gatattacta gaacaaaaca attagaacaa gagatggaac aaaaaaatct agaacttgaa
    25741 atgatatcag aaaatgtttt aggtggtata attataacag aatttaatga tgattttact
    25801 ataaaatacg ctaactctgg ttatctttca atgattggat atacacgtga acaattagaa
    25861 aatgaactta aatacaaagc ttgtaatctt gttttttatg aggataaaaa gaaggctctt
    25921 gaaagtatac aacatcaatt aaacacaaaa ggaatagctg tatatcaaca tagaataaga
    25981 agaagaaatg gtaatattat ttgggtttct ataaaaggaa ggcttattgt tgatgatggt
    26041 attgaaaaag gtatttggat tctaaatgat ataacagatt taaaaaatgc agaacaaaaa
    26101 cttaaaataa atgaagaaag atttagaatt gcattaaagc aaacatcaaa cactatattt
    26161 gagtatgata taaaaacaaa gtcactttta aatactagta aagagcttga taaatataat
    26221 atttataaaa ttactaaaaa cgttccatat tctctagtag aatcaggagt tattcataaa
    26281 gattttagtg atgattttat aaacatgtat gaaaatgtaa taaatggagc aaaaaaagca
    26341 agttgtgtag ttaagatgaa acttccagat gaaaattata tatggaataa agttaccttg
    26401 actactattt ttgatgaaga tggtaatcct gtaagagcaa ttggtataca ggaagatata
    26461 agcaaacaaa aggaagcaga gataagatac aatcaagaag gtaagtatca ttcagctata
    26521 ttgtcggaag caatgataac ttatgaaata aatgtatcaa aggatacttt tatcaaagga
    26581 aatgaaagtt ggcaaaaacc atttggaatt aagcctgaca ataactattc tcaaatggta
    26641 aaaactatag caaatagtat tgtacataaa gacaataaag aaacattttt aaatacattt
    26701 ttatgtgaaa acttattgga tgcatataaa aataatgtga ctgaaataaa attagaatat
    26761 cgaagaatga atcaagaaaa taaaatgatt tgggtcattt gtacaatgca cttaataaaa
    26821 gattctatta cgaacgatat aaaagcactt gcttatgtta aagatattga caagcaaaaa
    26881 aatgaagaaa ttagattaaa attaaaagct gaaagagata ctcttacagg attatataat
    26941 aaaggtacta cagaaaaatt gattaatgat ttcttgaact ctgaggaagc aagcttagga
    27001 atgcatgcat ttttaattgt tgatatagat aattttaaat ctgtgaatga taatttagga
    27061 catgtatttg gagataaagt attatttgaa gtttctaaaa acctaaaacc tatatttaga
    27121 aaagatgata tagtaggtag aattggtgga gatgaattta tagtattctt aaaaaatatt
    27181 cagtcttttg agaatatcaa aaagaaagca gaaaaaatat gcgatatatt tagaaattct
    27241 tatacagaaa ataaaaagac atataaaata tctggaacag ttggaatttc atttgtacca
    27301 gaacatggaa ctgtatttga agaactttat aaaaaagcag acatagcact ttattatgca
    27361 aagagcaaag gaaaagataa gtatgcactt tataatgatt gtatctacca aaatgaactt
    27421 gaaaataata taagtgataa taatataaaa ttagcagata aatgtgagaa atccaaacca
    27481 gtacttaaag aaattcttga ttctattgat aattatatct atatagtgaa tccaaatact
    27541 tatgaacttc tttttgtcaa taataaggtg tctcgtttgg atttagagat aaaattagga
    27601 gaaacctgtt ataaatcact attaaaatct gatagaccat gtaataattg ccctcttaac
    27661 ggattagaag aaaataagca ttcaaaattc aaaatagaga caaatacatt tggtaaaaat
    27721 atcagtatag caagttggat taattgcata gatggagaat acaactgtct tatagagtgt
    27781 atagattctt ctttatacaa aaataaataa aaaaggacta tgaagatatg ttaaatagta
    27841 taactttgat acttggtata atatttacaa tttactattt ttatctcaaa atagtttttg
    27901 gaggaatttc atttagtgag attttcttag ttgtaggaat tgtactaatt atctatcaaa
    27961 tatttaagaa aaaaattaaa gaaaagaagg ttttttatag ggtgttaaaa ataataatca
    28021 gcattttttt aatagtattt gtagttactg agagtctaat tattttttat cccaaaaata
    28081 gtttagaatc aaaaagtgat tatctcttaa ttttaggagc ttctgtaaaa aagactacac
    28141 caagtacaac cctgaagggt aggttagaca ctgcattgaa atacctaaaa attaatgata
    28201 attgttatgt ggtagtatct ggtggtaaag gaagtggaga aaaaataact gaggcaaaag
    28261 ctatgaaaga ttatcttata aaaaatggta tagataaaaa taggataata gaagaggata
    28321 aatccacgaa tacttatgag aattttaaat attcaaaatt gaagatagaa gaacatagtc
    28381 aaggaaaact aagcgattta aaagtaaaaa tagtaacaac agattttcat gttctcagaa
    28441 gtaaaatatt agcatataga aatggatata aaaatacgtc tttttatgct agtaaatcaa
    28501 aactttcatt tgtaccaact tactatacaa gagaattttt tgcattatgg aaaacaatca
    28561 tttttgatag ataataaata aaaagactag atataaactc atatctagtc ttttctattc
    28621 ccttaattct aatccatttt ccaactttac ttgttgtaga aatttcaaca ttgggattta
    28681 caagtaattg cttataagaa gttttatatt ttacgattcc aaaatataat tttccttcat
    28741 aatccattat aaatccgaat ggtcttactc ttggtttatt atcttcaact gtagcaaaat
    28801 agaatgttga gttttcttta aaaaaattca ttattttttc atgattaaat cctctttgta
    28861 tcttatacta atataatgaa tataaataaa atattcataa tactaatata aatcgatata
    28921 aaaacaatta caatattata ttgattattc aaaattatat ataaaattca gaaaaaaatt
    28981 ttagtttaca taataaaaat aaagtcaact aaaattattg attttagatt aaagtaccgg
    29041 attaagcatt taagtagatt ttaagcttga tttgattaga aaggtacaaa ctatcaccga
    29101 aaaaaattaa acccatttaa aaagcaatat aaaagcttgt tatttttgag aaaaatagac
    29161 cctctaaact caattagatt aaaaataaaa tacagaaaat tatatctcta aatatcttaa
    29221 ataattaagt ttaaatttta cgatattttg tttgatgatt tataatataa aagcatactc
    29281 ttaatcttca aaatttaaaa agagtaaaaa ataacaaaaa aatcactgac atttcactga
    29341 caaattgtaa ttttgttatt ataaatacat tgaaaatact tgattattga aaaatggcat
    29401 aaaataatac attttatgcc atttgctatt atttgatagt ttttaactta tgacataaga
    29461 tattttttaa catatacaat aaaatataaa aaaattgata ttgcaaataa aaaaaaatac
    29521 atattagatg ttatagaaaa aaagcgcact tataggctta aaatgtcaca taaaagagtt
    29581 ttaaagaata atatattatg aacacaaatt ttgtaatcac aaaggagtga taatatggca
    29641 acagtatcag gacaaatagt ttttgataga aatagaagtg ctaccattga ttctggagac
    29701 tcaggaatag ccaatatacc agttgtatta caagatatag caactggagt tagacttgtg
    29761 gttctcacag atgcatcagg aaattatgtt tttactaatg ttccaaatgg taactataga
    29821 attgtagaag cttttggaac tacaggagga gtaccaacac caggaaattt tgcaacagcg
    29881 atagtaggtc cagttccaat tgcagaaatg ccacctatta gttctgtgac aagtcctcct
    29941 attggttcaa caaacttaga tggtacaaca cctaacacac tattaataac agtagcaggt
    30001 tcagatataa caaatcaaaa tatattaaat gggcctgtga tttatacacc tatagagaat
    30061 atattggatt cttgcgtatc tgtatctaat ataaacctta ttacagatgc agataacgga
    30121 acattcggtt tttttccacc aggtacacca agtaatacag gacctgaaat agaaccttac
    30181 ccaaatgtga cgccagattt tacgtatgtt gtaccagacc caactaagtt tacaccttta
    30241 gatggagaat atacagtaca aaatattatg acaaatgcaa tgagtaatgt tataggagct
    30301 tggtggcgta ttgctgacca tactacagga aatgaaacag gaagaatgat ggtggtaaat
    30361 ggttttaatc ctggagctgt attttttaaa tcaacagtac aagttacacc taacactaat
    30421 tatttattta gcacttggat tttaaacctt tttaaggtaa caggatatcc accaccacag
    30481 ctaggtgtaa gaatatttga ccaaaataat aatatactat atcaagcaac attaggagct
    30541 caaattccag ttaatacaaa cgcaccagaa tggaaagaag taggtactgt gattaattct
    30601 caaaataata atcaacttac agtagaattt tttagtgaag gagaaagcgc cattggaaat
    30661 gactatgcta tagatgatgt ttctttaaga gaaatagctg ttccaacttt tactccaata
    30721 aaaacaagta acacagaaac tgctaatgta ggtgatataa tcacatatac agttacatta
    30781 gataatactt gtgatagccc tttaactaat gtatttttta gggatttaat tccaaatggt
    30841 ttagagttta tacctggaac tgtaacggtt gatggagtat ctgtaccagg agtagacccc
    30901 aatacaggtt tcccacttcc agatattgga ggaggaacag gggttgaagt aacttttgat
    30961 gttgtggttg aaagtattcc taacccaaat cctactaata atatagctac tatagattac
    31021 tcctatacac ctgtagaagg cggtatacca aatgattttt cagtagattc taatccagtt
    31081 cctgttgaag taatctcagc agatattgaa gttacaaaat tatctgaacc tactatagtg
    31141 aatccaggag aggaattaat atacactata aaagtagtaa ataatggacc attcccatct
    31201 gaaaatgtgg ttttaacaga tgatgtacca gcttctattg taaatccaga gtattcatta
    31261 gatggaggag taacttttca accatggact ggaagtttaa atatagggac attagaagta
    31321 ggagagacaa gagttattat aattaggggt attgtaaatc catcaacagt aggaattata
    31381 acaaatacag ctgtagtatc ttcaactaca gcagacccaa accttaataa taatacatct
    31441 acaatagaga cagaagtgaa tttattagca gatattttag taatgaaaac agcagaacct
    31501 aattcagctg ttccaggtac tttattgaga tatactattc aagtagaaaa cttaggacca
    31561 gcaaatgctg aaaatgtaat attaaatgat gatattccag cttctattat aaatccagaa
    31621 tattcattgg atggaggagc aagttttcaa ccatggaatg gaagtcttaa tataggaact
    31681 ttaaactctg gaatttcatt aacagtttta attcaaggaa cagttagttt aaattcttca
    31741 gaatatatag taaatacagc aacagtttct tcaactacac ctgacccaga tttaagcaac
    31801 aatatatcta ccattattac accagttaac ccacaagcag gtatttctat tataaaagta
    31861 gctgacgagg atgtagctgt tccaggagaa gaatttgtat atacaattga aatttttaat
    31921 gaaggaccat ctaatgctac gaatgtagtt ttaacagatg atataccaga tgttatttta
    31981 aatccagaat attcattgga tggaggagca actttccaac catggactgg aagtcttaat
    32041 ataggtacag ttgcaccagg gcaattaata agaattatca taaagggatt agtaagttca
    32101 actgctacag gagatattac taatacagca gaagtaagtg cagatgtacc agaaccagtt
    32161 acggattcat caacagtgac aactcctata gttccatcag cagatataga agtaataaaa
    32221 actagcaata tggatacagc agttccagga gaaactttca gttatactat aacagttaca
    32281 aatttaggac catctgctgc acaaagtatc gttttgacag atgatatacc agatgttatt
    32341 ttaaatccag agtattcatt ggatggagga gtaactttcc aaccatggaa tggaaatctt
    32401 agtataggca ctttggatgc tggagaaata agaagtatta taataagagg aacagtgagc
    32461 cagacagcag taggtacaat tataaataca gcaacaataa gttcaactac acctgaccca
    32521 aatccagata ataatacttc aacagatgaa acagatataa gtccattagc agatatttct
    32581 gtgataaaag gcaacgaacc agttgctata ccagggggaa gatttattta tggaattgaa
    32641 attgcaaatg caggaccatc ttttgcagag aacgtaactt taacagataa tataccagct
    32701 tctattttaa atccagagta ctcaatagat aatggagtga ctttccaacc atggaatgga
    32761 agccttaata taggtacttt agatgctgga gagataagaa atatcataat aaggggaaca
    32821 gtaagtcaaa cagcaatagg cacaattata aatacagcaa cagtaagttc aactacacct
    32881 gacccaaatc taaataacaa tatttcaaca tcagaagcag aggtaagttc atcagcagat
    32941 atttctgtag taaaacgaag caatcagact gttgttgtac caggagatgt actagactat
    33001 acaattgagg tgagaaatgc aggaccgtct actgctcaga acgtaacttt aacagataat
    33061 ataccagctt ctattttaag tccagaatat tcaatagata atggagtgac ttttcaacca
    33121 tggaatggaa gtcttagtat aggcacttta gatgctggag agataagaaa tattataata
    33181 aggggaatag taagtcaaac agcaataggt acaattataa atacagcaac agtaagttca
    33241 actacacctg acccaaatcc agataataat acttcaacat cagaaataga tataagttca
    33301 tcagcagata tttctgtaat aaaattagca aataaaacag aagcatgtgt aggagagcaa
    33361 atagattttg taatagtagt atcaaatgca ggaccagaaa atgctcaaaa tgttacttta
    33421 atagacaatg tttcagataa gcttaagaaa gcagtatttt cacttgatag aggtgtaagt
    33481 ttccaaccat ggactggaag tcttaatata ggtacactac cagctggaac tttaagagtg
    33541 attatattaa gaggaattat aaaatcaaca tgtcttgata gattaacaaa tattgcagaa
    33601 attacttcaa caacaccaga ttcaaacctt aacaataata tatcaagagt gcaagtagaa
    33661 ataaaacaat gttgttgtaa tgattgctgt tgtaacaact gtagtaattg ttgttgcaat
    33721 gattgtggtt gtaaagattg ttgctgtaat tgttgtaaaa atgacttttg gtgttgattt
    33781 tataaaataa ttttgtatac cttaaattaa actgaaataa aaaataaatt cacatatgag
    33841 taaaatattt tataaatatt aataaatttt ctatctttga tatggaccac attcgtaata
    33901 ctagttatta aatgaagtgg tcctttttaa ttcattaaaa ttatttattc taattaaa
//
LOCUS       DAEHWO010000041        33597 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEHWO010000041 DAEHWO010000000
VERSION     DAEHWO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33597
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.041"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            97..1383
                     /locus_tag="KNP54_002264"
     CDS             97..1383
                     /locus_tag="KNP54_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBF0893162.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            1495..1968
                     /locus_tag="KNP54_002265"
     CDS             1495..1968
                     /locus_tag="KNP54_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1627..1629,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBF0893163.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            2000..3310
                     /gene="grdB"
                     /locus_tag="KNP54_002266"
     CDS             2000..3310
                     /gene="grdB"
                     /locus_tag="KNP54_002266"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:3047..3049,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBF0893164.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            3566..5098
                     /locus_tag="KNP54_002267"
     CDS             3566..5098
                     /locus_tag="KNP54_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBF0893165.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            5109..6254
                     /locus_tag="KNP54_002268"
     CDS             5109..6254
                     /locus_tag="KNP54_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBF0893166.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            6564..7643
                     /locus_tag="KNP54_002269"
     CDS             6564..7643
                     /locus_tag="KNP54_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBF0893167.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            7756..8355
                     /locus_tag="KNP54_002270"
     CDS             7756..8355
                     /locus_tag="KNP54_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893168.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(8541..9413)
                     /locus_tag="KNP54_002271"
     CDS             complement(8541..9413)
                     /locus_tag="KNP54_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0893169.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            9830..11233
                     /locus_tag="KNP54_002272"
     CDS             9830..11233
                     /locus_tag="KNP54_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893170.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            11260..12804
                     /locus_tag="KNP54_002273"
     CDS             11260..12804
                     /locus_tag="KNP54_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBF0893171.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            12835..14226
                     /locus_tag="KNP54_002274"
     CDS             12835..14226
                     /locus_tag="KNP54_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBF0893172.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            14419..15915
                     /gene="abfD"
                     /locus_tag="KNP54_002275"
     CDS             14419..15915
                     /gene="abfD"
                     /locus_tag="KNP54_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBF0893173.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            16050..16325
                     /locus_tag="KNP54_002276"
     CDS             16050..16325
                     /locus_tag="KNP54_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893174.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            16349..17656
                     /locus_tag="KNP54_002277"
     CDS             16349..17656
                     /locus_tag="KNP54_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBF0893175.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVREHLAVEFEKRFKEKY"
     gene            17676..18794
                     /locus_tag="KNP54_002278"
     CDS             17676..18794
                     /locus_tag="KNP54_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBF0893176.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            19081..20001
                     /locus_tag="KNP54_002279"
     CDS             19081..20001
                     /locus_tag="KNP54_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBF0893177.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            20116..21273
                     /locus_tag="KNP54_002280"
     CDS             20116..21273
                     /locus_tag="KNP54_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBF0893178.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(21358..22857)
                     /locus_tag="KNP54_002281"
     CDS             complement(21358..22857)
                     /locus_tag="KNP54_002281"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBF0893179.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            23453..24877
                     /locus_tag="KNP54_002282"
     CDS             23453..24877
                     /locus_tag="KNP54_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBF0893180.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            24912..27041
                     /locus_tag="KNP54_002283"
     CDS             24912..27041
                     /locus_tag="KNP54_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBF0893181.1"
                     /translation="MKKKKITSRQKKIILMIVANSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEWVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDVVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            27071..27493
                     /locus_tag="KNP54_002284"
     CDS             27071..27493
                     /locus_tag="KNP54_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0893182.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            27512..28663
                     /locus_tag="KNP54_002285"
     CDS             27512..28663
                     /locus_tag="KNP54_002285"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBF0893183.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      28769..28870
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            29053..29625
                     /locus_tag="KNP54_002286"
     CDS             29053..29625
                     /locus_tag="KNP54_002286"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBF0893184.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            29689..30339
                     /gene="fsa"
                     /locus_tag="KNP54_002287"
     CDS             29689..30339
                     /gene="fsa"
                     /locus_tag="KNP54_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBF0893185.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            30491..33415
                     /locus_tag="KNP54_002288"
     CDS             30491..33415
                     /locus_tag="KNP54_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893186.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVMKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        13200 a         3751 c         6324 g        10322 t
ORIGIN      
        1 atatatcttt aaaaaaataa gataaattgt aaaatgatat aattttgaga aaaactcaaa
       61 tgcatataca caaattaaat aacaggaggt gcaagtatgc gtcttgaatt agggaaaatc
      121 tttataaaag atattcaatt tggtgatgta acagaagtaa aagatggagt attattcatc
      181 aataagcaag agatgctaca agaaattggt ggagatgagc atattaaatc tatagatata
      241 gaattagctc gtccaggtga aagcgtaaga ataacacctg taaaagatgt tattgagcca
      301 agagtaaaag ttgaaggtaa tgggggaatc ttccctggta tcatgtctaa agttgacact
      361 gtaggagaag gaaaaactca tgctttaaaa ggtgtagctg ttgtaactac tggaaaaata
      421 gtaggtttcc aagaaggtat aatagacatg actggagaag gagctaagta cactccattt
      481 tctaaattaa ataatgtagt agtaatagct gaacctattg atggtttaaa acaatacgct
      541 catgaaaaag ctgttagaat gataggattc aaagcagcaa tgtacttagg agaagtagca
      601 agaaatctta ctccagatga agtttcagta tatgaaacta aacctcttct tgaatcaata
      661 aaagaatatc cagagcttcc aaaagtagga tatgtttaca tgcttcagac tcaaggttta
      721 ttacatgata cttatgtata tggagtagat gcaaaacaaa tagtaccaac tttattatat
      781 ccaacagaat taatggacgg agcaattgta agtggtaact gtgtttctgc atgtgacaaa
      841 aacccaagtt atgttcatat aaacaatggg gttgttgaag acttatatgc aagacatggt
      901 aaagatataa actttgtagg tgtaattata actaatgaaa atgtttatct agcagataaa
      961 gaaagatctt caaactggac ttctaaatta tgtaaatatt taggattaga tgcagttata
     1021 gtttcacaag aaggttttgg aaatcctgat actgacctta taatgaactg taagaagata
     1081 gaaatgcaag gtgttaaaac agttatagtt acagatgaat atgctggacg tgatggaggt
     1141 tctcaatcac ttgcagatgc agatgtaaga gctgatgctg ttgtaacagg tggaaatgcc
     1201 aaccaagttg tagttcttcc taagttagat aaagttattg gacatttaga agtagtagat
     1261 gtaatagctg gtggttctga tggaagttta agagctgatg gaactattga agttgaaatc
     1321 caagctataa caggtgcaac taatgaaaca ggatttggtc atttaactgc taaaggatat
     1381 taagaagtat tttattaaac gattgagtaa tgttaataaa acatattata gataattata
     1441 ataagtgtta tagatatata aaaatatatt agaaatataa taaggaggat tattatgagt
     1501 ttacttagta ataaaaaggt tcttataata ggtgaccgtg atggtatacc aggacctgcg
     1561 atagaagaat gtgtaaaaac agtagaagga gcagaggttg ttttctcatc tacagaatgc
     1621 tttgtctgaa cagctgctgg ggctatggac ttagaaaatc aaaacagagt taaagatgct
     1681 gctgataaat tcggagctga aaatgttgtg attttactag gtgctgctga agccgaagct
     1741 gcaggtcttg cagccgaaac agtaactgct ggagatccaa ctttcgctgg accacttgct
     1801 ggagttgcct taggattaag tgtttaccac gttgttgagg aaccaataaa atcattattt
     1861 gatgaaagtg tatatgagga ccaaataagt atgatggaaa tggttttaga agttgaagaa
     1921 atagaagaag aaatgtctgg tataagagaa gaattttgta aattttaatg cctaaaagca
     1981 aaaggggtga aactaagaga tgggaaaact aaaagcagta cattatatta atcagttctt
     2041 tgctggtata ggtggagaag aaaaagctga tactaagcca catgtggcag aaactttacc
     2101 tccaataagt ttacaacttg ataaattatt aggtgaagat attgaaatag ttggaacagt
     2161 agtttgtgga gatagctatt tcaatgaaaa tatagatagt gcaagtgaag aagttttatc
     2221 aatggtaaaa ggttttgaac cacaactttt catagctggt cctgcattta atgctggtag
     2281 atatggggtt gctgctggaa caataactaa agttgtaaaa gatgctttga atataccagc
     2341 tttaacaggt atgtatgttg aaaatccagg agcagatatg ttcaaaaagg atgtttatgt
     2401 agtagaaact tctgattctg cagcaggtat gagaaaggca cttcctaaga tagctaaact
     2461 tgcagtaaaa cttgctaatg gagaagaaat tggaactcct aaagatgaag gatacatagc
     2521 tagaggaata agagttaact acttccatga agacagaggt tctaagagag ctgttgacat
     2581 gttagttaag aaaataaaag gtgaaccatt tgaaactgaa tacccaatgc caaactttga
     2641 tagagttgac ccaagtaaag ctgtaaaaga tttatcaaaa tgtaaaatag ctttagttac
     2701 ttctggtggt atagttccaa aaggaaatcc agatagaata gagtcttctt cagcttctaa
     2761 atatggaact tattctatag caggagttat ggatttaaca gaagagactt atgaaactgc
     2821 acatggtgga tatgacccag tgtatgcaaa tttagatgca gatagagtat tacctgttga
     2881 tgttcttaga gatttagaaa aagaaggtgt aattggaaaa ttacatgaga ctttctatac
     2941 aactgtaggt aatggtacat ctgttgcaaa ctctaaaaaa tatgcttctg aaattggagc
     3001 agcattagtg gctgatggtg tagatgcagt aatattaact tctacatgag gtacttgtac
     3061 tcgttgcggt gcaacgatgg taaaagaaat agaaaaaact ggacttccag tagttcatat
     3121 gtgtacagta gtacctattt cattaacagt aggggctaat agaatagttc caactatagc
     3181 aatacctcat ccacttggaa atccagcgct tgaccctaca gaagaaaaag ccctaagaag
     3241 aggccttgta gaaaaagcat taaatgcttt aactacagaa gtagatggtc aaacagtatt
     3301 tgaaaaataa aaataacaca cacatatatt atatagataa aaatataaac acacactaaa
     3361 aataaaaaat aactatacac aaaaaaataa tatagatttc atgaatggat aaattggagt
     3421 tattcattca tgaaatctta aaaaatgcca aaatacataa acaataatag aatcaaatat
     3481 acaataaaat acaatgatta gagcttttaa taagtttaat aagattaaaa aataagtgtt
     3541 cataaaattt atggaggtgc acaaaatgac ttatccagtt ttaaaagggg caggctatgt
     3601 acttattcat actccagata tgatagtgca aaatggaagt acttgtacag ttgaaagagc
     3661 aacaaatcca gattcagaat ttttaaaaga agtaagtaat catataagaa gttatgaaga
     3721 tgtagttaac tacatgccaa atcaagttta tataggaaat agaagaccag aagaattaag
     3781 agatttacca atgccatggt gtgaacaaaa gattgaggga actagaaatg gtaagtttgg
     3841 agaaataatg cctcaagatg agttcatagc tttaatgcaa ataagtgatg catttgattt
     3901 agtaaaatta tcacaagaat ttattgatga agtaaagcca aaaatcgaaa ataactaccc
     3961 tgaaattgca ccatttgtag gtaaattaaa gggtgatgat atagaagaag gtaaagaatt
     4021 agtagcaaca cacatagctg aaggattata ccatgatgga aaatttgttg gttatgtaaa
     4081 aagagcacat gatgtagatg ttaacttaaa tgcccataca atgtttgaaa atctagtagt
     4141 aaaagcatct ggagttttat ctgctattca aatgctaaga catagcaaaa tagaccctgc
     4201 tgaaatagat tatgttattg agtgttcaga agaagcttgt ggagatataa accaaagagg
     4261 tggaggaaac tttgctaaat caatagctga gatagcagga cttcaaaatg caactggttc
     4321 tgacacaaga ggattttgtg cagcaccaac tcatgcatta attcaagcag cagctttagt
     4381 aaaagctggt atacataaaa atgtaatggt agtagcaggt ggagcaagtg ctaaacttgg
     4441 aatgaatgct aaagaccatg ttaaaaaagg tcttcctgta cttgaagatg ttgttggagg
     4501 atttgcagta cttgtatctg aaaatgatgg tgtaaatcca gttataagaa ctgatttaac
     4561 aggtaagcat actgttggaa ctggttcttc accacaagca gttatgacag cacttataac
     4621 ttcaggtctt gatagagcta atttaaaaat aacagatgtt gatgtgtatt cagttgaaat
     4681 gcaaaaccca gatataacta agccagcagg agcaggagat gttccagaag caaactacaa
     4741 aatgataggg gcacttgctg ttaaacgtgg agacttagaa aagaaagaat tgaaagattt
     4801 tgtttctaac aaaggattac caggatgggc accaactcaa ggacatatac catcaggagc
     4861 tccttatata ggatttttaa tagatgattt aactacagga aatagaaata gagctatgat
     4921 agttggaaaa ggtagtttat tcttaggaag aatgactaac ttatttgatg gagtatcttt
     4981 tatagctgaa agaaatacag gtgttactga agagacttca ggaatatcta aggatgaaat
     5041 taagaagata atagctgaat ctatgaaaaa actagcatta gatatgttag aagaataggg
     5101 gtgaggatat gtcaaaaaaa gtaatcgcag atgtattctt agaagtagct aatgcaatag
     5161 aaagcggcga atttggcaaa aaagtaaaaa ttggtgttac tacacttgga agtgaacatg
     5221 gtgtagaaaa catggttaat ggtgcacaat tagcaaaatc taatttattt gatattgtgc
     5281 ttattggacc aaaagtggaa actgaccttg aagtagttga agttaatgat gaaaaagaaa
     5341 tgcatgcaaa aatggaagaa ttattagatt caggatatat tgatgcttgt gttactatgc
     5401 attataattt tccaataggt gtatctacag taggtagagt aataactcca gcaaaaggaa
     5461 aagaaatgat acttgcaaca acaacaggaa caagtgctac taatagaata gaggcaatgg
     5521 taagaaatgc catttatggt attgctacag ctaaatcaat gggtaacaaa tgcccaaaag
     5581 ttggaatact taatgttgat ggagcaagac aagttgagaa gtgcttaaaa gaattaaaag
     5641 ataatggata tgacatggag tttgcggatt caattagagc agatggtgga tgtgtaatga
     5701 gaggtaatga tttacttgta ggtgcacctg atgttatggt tactgataca ttatctggaa
     5761 atatatttat gaaagtattt tcttcatata ctacaggtgg agattatgaa gctcaaggct
     5821 ttggatacgg acctggagtt ggagaggact atgatagaaa ggtacttata gtatcaagag
     5881 catcaggttc tccggtagta gcaaatgctt taaaatacgc ttatgatgtt gtaaagggag
     5941 atataagtaa tgttgcaaga aatgaatttg caaaggttaa aaaagcaaaa tttgatgaca
     6001 ttatatcctc tcttactaaa aaagaagtta aagctgaaaa agtagaagtt aaaatgccag
     6061 ataaagaaat tgttactcgt caaatagctg gtgttgatat aatggattta gaagatgcag
     6121 tatctgagtt atggaaaaac ggaatctatg ctgaaagtgg tatgggttgt acaggtccaa
     6181 tagttttagt aaatgaagct aaaggagact tagcagttga aactttagtt aaagctggat
     6241 atactgcaaa ataagtacat tttttatatg taaataagaa catatagtta taattttatt
     6301 gattataatt atatgttctt tttattttat atcttgtcaa tatttatata ttaacacaat
     6361 ccatttattt gattctctag ctaatttatt atatttattc agttaaaatt aagctttcta
     6421 actaaataaa aactaatgaa gtattaaaat gaaattgata aaatatgaaa aaattttagg
     6481 aataaagtat ctgttagata aaaataagat taattagtga tataatataa ttaagataaa
     6541 atttattatt tggaggcaaa atcatgagca gagtaaaaaa tgtagtagaa ttgttggaaa
     6601 ctaaaggtgt tgatgcacta tatctaacaa agaaaactaa tgtaaactat ataagtggtt
     6661 ttcctgatga agaagcatat gcagtgattt gcaaagatgg aaacttttta gttactgata
     6721 gtagatatat ggagcttgca gaaaaggttt gcaaagattt tgaaattata aattggcata
     6781 attttgatag aagtgtggca aaggcagtta aaagtgtatg tgataaagtg ggtataaaga
     6841 aacttgggtt tgaaagaact aatatagtgt ttgataaata tgaagaactt aaaaatctga
     6901 ttgagaagga taatggagaa ttaataccta cagaaaatat tgtagagact ttgagatatg
     6961 taaaagacaa agatgaaatc aaaaatacaa gaaaagcttg tgaaatagcg gataaggcat
     7021 tagaagaatt gattccacat ataaaagctg gagttagcga aattgaactg gctacaaagt
     7081 tagagtactt tatgaaaatg aacggagcac aaaatatagg gtttgaaact atactgatat
     7141 caggagcaaa gacttcattg cttcatggta agcctagtga taagattata gaaaaaggtg
     7201 attttgtact tatagactat ggcgctatgt ataatggcta tatatctgat acaactagaa
     7261 cttttatagt tggaggagct tctgaaaagc aattagaaat atataattta gttaaggaag
     7321 ctcaaaatgt aggggttgag aacatgaaag ctggtgtaca tgcgacaatt ccagatgctg
     7381 agataagaaa agttgtcaaa aaatatgaag actattacta tcaaggtata ggacatggag
     7441 tcggtagaga tgttcatgaa gaacctttca ttggtaatta tggtgataaa atcatagaag
     7501 agggatgtat aataacaatg gaaccaggta tttatttccc tggatggggt ggagttagaa
     7561 tagaagatac tgttttgatt actaaaaatg gtccagaaag acttactaaa ttccctaaag
     7621 atttgatgat tttagacaaa taatttaatt tatatatatt tttttacata aaatataaca
     7681 taatctcact attaagctct atttacatat tatagtaaag agggcttaat tttattgtga
     7741 gaggtgatag tatatatgta taaaaaacat aaatttataa aaaatataaa aaaagcctgg
     7801 tataaaatca aattaattga tagatgcctt ataattgtaa tggcaatatt aatgtttcaa
     7861 tctatatata atttatttgt taatgaagta aattcacaag atactacaac tattgatgta
     7921 gtagtaagaa ccacttcagc agctatattt gggtattttt taagtgctaa ttttataaag
     7981 agacctttaa ggaagtatac aaatactgat gtatcttcaa atctttttat agataataat
     8041 ttatccccaa aaggtcaaga gtctaatcaa aataatataa tgaatgtcaa aaataccatt
     8101 ggatttactt cagaagctga taattatgaa aagaaaatac ctattaataa taatgaaggt
     8161 tttgaagaag gagaaactag tgaattgcaa attattatag ctactgtaat ttgtatagta
     8221 gcattaacag tactttttgt tgtaagaaat tttacaacta caacatcagc ttctttaggt
     8281 actatttcac agatgagaga ttttgtctca ggatgcgtgg gttttttgct aggttgtcca
     8341 agtaaacctg attaaaaaag tattatcaat aaaaggtatt ttaaaaagta tcagtataat
     8401 aatatttaga tttaaatgta tacaattata attctaaaca ttctatattg tatttttata
     8461 ctgatactct aaactatact atttattaaa atattttaac attgtattta aacaaaatat
     8521 tatatctgta taatataaat ttagtttata tgaatagatg ccatatactc aataaaaagt
     8581 ttcatactat gagatatgta ttgatttctt ctccaaagaa ccccaatatt cgcagtaatt
     8641 gcacgttcta atggtattga acagagattt tctgtatttt gaaatatttc tttatacaat
     8701 attgttgaag ccaagtcatt ttctagtaaa taacgtatgg tagaaagttg atttgagtgt
     8761 aaaattatat ttggcttagc tttttcaagt ctttttgtaa taatcttata gtgataagaa
     8821 ccttcagata agattacaaa aggtacattt tttaacatat aattcgatat aatgggatgt
     8881 tttgccaatt catttttggg atttgtaact aagtataatt ctgttttata gattgtcttt
     8941 gaatctatat catcataaat atcactgtca attataccaa tacaaaaatc aagtgtagat
     9001 tcttcaatca ttttagctcc aacaaatgtt ggaacttcaa aaattttaag ctctatatct
     9061 ggataaatta cattaaatct aggaagtatt tttgaaagca aaaacgtacc taaaactgta
     9121 ggaataccta ttttgagaga agcttttctc ttttttccta aatcaagtgc gtcacattga
     9181 aaatcctcaa attgttttat aaaatgtttt gacttgtcta aaaaaatttt tccttcaggc
     9241 gttaactcta ttttattacc tattctgtaa aaaagttcaa agccaagttc tttttctaat
     9301 tctttaattg ctaatgttat ggatggttga gaaatatgaa tactttccgc agccttagtc
     9361 atgtttttat atttacagac agtttgaaaa tagtataaat agtttatatt catttggtat
     9421 tagttccttt catttacata ttagtgacaa gtatataatt aacaatagca taagttttgt
     9481 atattgttgt aaaaaaatag aatagtttta aactatcata gcataagttt ttgatatttt
     9541 caatctatta agaatagtgc tattattaaa ttaacaaaag agaatagctg gtatggttta
     9601 gagtaaatca atctatatta cagttatatc aacgaatatc aaaaaattat ctattagaaa
     9661 ataaaaatta tttttacaat taaattgtta attaaatcat aaagaaaaaa gtgatattaa
     9721 caagataaaa tttttttaat cagaaatgtt aatttaataa caaaatagag tattggggag
     9781 aaaggagaaa tatatttttt aataatattt gttaatttaa taacgaaaaa tgaaagggag
     9841 tgatttagtg aagtttgaat tgatggattt tttaatgaat ccttttgtcc ttatgtttgc
     9901 tgcagtaatt acaggaattt tatttggaaa aattaaattt gggaagttta attttggggt
     9961 atcaggagca ttatttacag gattatttat tggatggctt gcatatagct tggggaatct
    10021 aataatagca aaaggggaaa cagcagcagg atataaggca gcaactgtaa tgatgggtaa
    10081 tggaattatt tcttctgact tctttgattt ctttttaata atatttgttg cagcagttgg
    10141 tctattggca gcaaaagata tgaaagctgt attaaagaag tatggagcaa gatttgtaat
    10201 tttaggagtt cttataactt ttataggtgg ctctatgact tatgcaatga ctttactatc
    10261 aagtgataaa ggaagtagtg cttatgaagt ttctggcgtt tacacaggag cattaacaag
    10321 ttcgcctgga ttagctgctg ctttagaaac agctggtaaa catgcagaag atgtatcaaa
    10381 agaatttgaa aaagcttcaa taaaagataa aaaagaaatt ttaaaagtag tcgacccaga
    10441 aggcaaattg gatgtgaata caactacatc actgactcaa gagcaaatag ataagtatat
    10501 tgcatatgct gaagctggtg ttggtatagg tcatgcagtc gcatatcctt ttggagtttt
    10561 aatagtaatc ttaggtgtaa atttccttcc aaaattattt aggatggacc taaaagaaga
    10621 aagaagaaaa tatgagaagg aaatgaagga agcaagagat agtgtttctg gtaaaacgat
    10681 accagaagtt ccatttaata taataacatt tttcttgaca tgtttagctg gatacttagt
    10741 tggaggaata catgtattta tgggaccact agggtacttc acactaggcg caacaggagg
    10801 ttcactaatt gtatctctag ttcttggata tataggtaag ataggggtag taaatttcag
    10861 aatggaagaa aaggttttaa atattttaaa acaaataggg ctagtatttt tcttagcaat
    10921 agttggatta agatatggtg gaaaagtagt tgattcaatt atgacatctg gtatgcacct
    10981 agccttagta gcaatagcag taggtgttac agctatgatg ataggattct tagttggcaa
    11041 atacgtattt aaattaaatt ggattttatt atctggagct gtctgtggtg gtatgacatc
    11101 aacaccaggt cttggagctg ctgttgatgc tcttgatagt gatgacccag cagcaggtta
    11161 tggtgctacg tatccatttg cattattaac taaagttata ttggttatag ttttacacaa
    11221 acttccaatg taaataagat tttatatggg gggatattta tgaataatga aggagcattt
    11281 gaagaattaa gtggaagatt aagaaataaa gaattgtgtg atttaataat gaatgcagat
    11341 gaagctgcta aaattataga ggatggcatg gttattggag ttagtggatt tacaccttca
    11401 ggctatccaa aagcagtacc attagcagtt tcagaaagag ctaaaagtgg agaaaagata
    11461 aaattaaccg tatattcagg agcatcttta ggtccagaag ttgatggagc atggtcagaa
    11521 gcaggtataa ttgaaagaag acttccttat caaactaatt caatacttag aaataatatt
    11581 aataaaggtg ttgttgatta tatagatatg cacctaagtc attctactca atttttaaat
    11641 tatggaacta tacctaaagt agatgtagct atagtagaag cacttgcaat aactgaagaa
    11701 ggaaatatta taccaactag tgggataggt aattctccat cttttataaa aagtgcagat
    11761 aaagtaatag tagagataaa tcttgcaaaa ccaatggaaa tggaaggtat ggcagatata
    11821 tatattacgg aaaatccacc aaatagaaaa ccaatagaaa taaatcatcc taaggataga
    11881 attggaacaa catatatacc ttgtggtttg gataaaattg caggagtagt aattaccaat
    11941 atgcaagata agacccgtcc attgggagtt gtagatgaag cttcgaaaaa aatatcaaat
    12001 aatattattg cttttttaag agaagaagta aaggcaggca gattatcaaa gaatttactt
    12061 cctcttcaat ctggtgtagg aagtgtagca aatgcagtat tatatggatt atgtgaatct
    12121 gaatttgaaa atttaacttg ttatacagag gttgtacagg actctatgtt ggatttaata
    12181 agaatgggta aagttacaat ggcatctact acatctgtaa gtccatctcc agaaggatta
    12241 ataaaatttg aaaaagatat tgattttttt aaggataaga ttatattaag acctcaagaa
    12301 attagtaaca atccagaaat agccagaaga attggtgtaa ttgcaatgaa cactgcaatt
    12361 gaagttgata tttatggaaa tgtaaattct actcacataa tggggtcaaa gatgatgaat
    12421 ggaattggtg gttctggtga ttttgctaga aatggagcaa taactatatt tagtactgag
    12481 tcaattgcaa aaaatggtga tatatcatca atagtaccta tggtatctca cgtagaccac
    12541 actgaacatg atgtaatggt aattgtaaca gaacaaggat atgctgattt aagaggtctt
    12601 gcacctagag aaagagctat aaaaataata gaaaattgtg cccatccaga ttataaagaa
    12661 caacttaggg attatttaaa tagagcttgt aaaagtggag caaaacaaac acctcacata
    12721 ttggacgaag ctttatcatg gcatagtaaa tttatgagta caggtacaat gaaaaaggct
    12781 gaaactttta aaagtgcatt ataaaatatt taataaattg gaggtagatt ttaaatggaa
    12841 aaagcagtgg aaaactttga agatttaagt aaggaataca ttaatggtta tattgagaga
    12901 gcaagaaaag ctcaaagaga gtttgaatgt tatactcaag aacaagtaga taaaatagta
    12961 aaaatagttg gaaaagtagt gtattataat gctgaatatt tagctaaact tgctgtagaa
    13021 gagactggaa tgggagtata tgaagataag gtagctaaaa ataaaagcaa agcaaaagtt
    13081 atatataaca atttaaaaga taaaaaatca gttggtataa ttgatataga tagagaaact
    13141 ggaataacaa aggtagctaa accagttgga gtagtagcgg caataactcc ttgtacaaat
    13201 ccaatcgtta cacctatgag caatgcaatg tttgcactta agggaagaaa tgcaattatt
    13261 atcacacctc atcataaagc aattggatgt agtacaaaaa ctgtagagat gattaatgaa
    13321 gaattagaaa aaataggagc tccagaaaat ttaatacaaa tacttgacca acaatcaaga
    13381 gaaaatacaa gaaatttaat ttcatcagca gatgtagtaa ttgccactgg aggaatggga
    13441 atggtaaaag ctgcgtactc aagtggaaaa ccagcacttg gtgtaggggc aggaaatgtt
    13501 caatgtatca tagatagaga tgtagacatt aaagaagcag tacctaaaat catagcagga
    13561 agaatttttg ataatggtat catttgttca ggtgaacagt cagtaatagt agcagaagaa
    13621 atgtttgata aaataatgga tgaatttaaa aataataaag gttttatagt tagagataaa
    13681 gtacaaaaag aagctttcag aaatgctatg tttgtaaata aatctatgaa taaagatgca
    13741 gtaggtcaat cagttcatac aattgcaaaa attgcaggtg ttgagatacc agaagataca
    13801 aaaataatag taatagaagc tgatggacca ggagaagagg atattattgc aaaagaaaaa
    13861 atgtgtccag ttatatctgc atacaagtat aaaagttttg aagaaggtgt agctattgca
    13921 aaagcaaatt taaatgtaga aggaaaagga catagtgtat ctatacattc aaatacagtt
    13981 aaaaatatag aatatgcagg agaaaatata gaagtatcaa gatttgttat taatcaatgt
    14041 tgtgctacta gtgctggagg aagtttcttt aatggtcttg cacctactaa tactctaggt
    14101 tgtggttctt ggggaaataa cagcatctct gaaaatcttg attataagca tctaattaat
    14161 atttctagaa ttgcttatta tatgccagaa aatgaagtcc ctacagatga agaactttgg
    14221 ggataaaatt tagacaaaaa atattcattc taaattaaag taggaatata ttttaattta
    14281 gaatgaattt aagacataaa ttaaatttaa attagtttat tggactaaat ttaaaatatt
    14341 aagagacata tagaagaagg aagtattata atttaaaata aataaaaaaa tctataaaag
    14401 agaaggagtg gttttattat ggcattaatg acaggagctc aatatattga aagtttgaga
    14461 aaattaaata ctaaggttta tatgtttggt gaagaggtta agaattgggt tgaccatcct
    14521 atgattagac catctataaa ttgtgtagca gcaacttatg acttagctca tgacccagaa
    14581 tatgcagatt taatgacagt tacttcaaat atcacaggtg aaaaaataaa tagatttggt
    14641 catcttcatc aaagtgttga tgatttgata aaaaaagtaa aaatgcaaag actatgtggt
    14701 caaaaaacag cttcttgttt ccaaagatgt gttggtatgg atgcgtttaa tgcagtgtat
    14761 tcaacaacat ttgagtgtga taaagcccat ggaactaatt atcatgataa ttttgtaaaa
    14821 tacttaactt atatacaaga aaacgattta gtagttgatg gagctatgac tgaccctaag
    14881 ggagatagaa gtctatcacc tagtgctcaa cctgacccag atatgttcct tcatatagta
    14941 gaaagaagag aagatgggat aattgtaaga ggagcaaagg cacatcaaac tggttcaata
    15001 aattcacatg agcaccttat aatgcctact ataagtatga ctgaagcaga taaagactac
    15061 gctgtatcat ttgcagttcc ttcagatgct gaaggagtgt ttatgattta tggaagacaa
    15121 tcttgtgaca ctagaaaatt agaagaaggt gcagatgttg atttaggaaa taaggagttt
    15181 ggaggtcaag aagctttagt agtatttgat aatgtatttg ttccaaatga tagaattttc
    15241 ttatgtggag aatgggattt ctctggtatg ttagtagaga gatttgcagg ataccataga
    15301 caaagttatg gtggatgtaa agtaggagta ggtgatgtaa taataggagc agcagcttta
    15361 gcagctgatt ataatggagc aaacaaagct tcacatataa aagataaact aatagaaatg
    15421 actcacctta atgaaagctt atattgctgt ggtatagcat gttcatcaga aggtcacaaa
    15481 acagaagctg gaaactatca aatagattta cttcttgcaa atgtgtgtaa acaaaatgta
    15541 actagatttc cttatgaaat agtaagactt gcagaagata tagctggagg gcttatggtt
    15601 actatgcctt cagaaaaaga ctttaaatca gaccttaaag ttggaacaag tggaatgact
    15661 attggcgaag tatgtaacaa gtattttaaa gcttcttcag tggcttcaac agaagaaaga
    15721 atgagaatat taagattctt agaaaatata tgccttggtt catctgctgt tggttataga
    15781 actgagtcaa tgcatggggc aggttcacca caagctcaaa gaataatgat ttcaagacaa
    15841 ggaaacataa atcaaaagaa agaattagct aagaaaattg cgggaataaa aaaagaggaa
    15901 gctttaaatt tataaaaagt tgatatataa agggaaatta tatattaatg tgtgttaatt
    15961 aatgaaaaaa tatgtagtat aagagatagt tataaaatta tggtggtttt tagctaagta
    16021 aagaaatttt taataaggag aatttacaca tgacctgtgg agttagattt tgtgggggct
    16081 gtaaccctag atacgaaaga gggaaggctc ttacaataat caaagagcac ttcaatggta
    16141 gggtagattt tagtatagca caagagaacg tcgagtatga tttgttactt ataattggag
    16201 gatgcgcaac tctatgcgca tcctatcaac aatataaagt gaaaaatgaa tgtgttaaga
    16261 tgtgggattt tagccatata gaaagagtta taaatgtgat tgaatcagca atttgtgaaa
    16321 cttaaaaaag ctaaatgggg ggatttcatt gagttggcaa gaattgtatc aaagtaaatt
    16381 atgtagtgct acagaagctg taaaacagat taaaaacggt gatactgtag tatttgcaca
    16441 ttgtgtaggt gaacctcctg cactagtaga agctatgatt gaaaatgctg aacaatataa
    16501 agatgttgag attaaacata tggtaagctt gggtagtggt ggatatactg ctaagggaat
    16561 ggaagctcat tttagagtaa atccaatgtt tgtaagtgga aatgtaagaa aggcaattga
    16621 aaatggagat ggtgatttta cacctgcatt cttccatgaa gtaccaaagt tgcttagaga
    16681 aaaaagatta aaatgtgatg ttgttttagc acaggtaact ccaccagatg aacatgggta
    16741 ttgtagctta ggaacatcag ttgattatac ttatgaagcc attaaaactg ctagaacagt
    16801 aattgttcaa gtgaatgacc agtttcctag aacctatggt gaggtagtcc atgtatcaga
    16861 gtttgactat atagtggaaa aatcacaacc tttatttgaa ctacaacctg caaagattgg
    16921 agaagtagaa gaagcaattg gtaaaaattg tgcttcatta attgaagatg gctctacttt
    16981 acagctaggg attggtggga taccagatgc agttatgtta tttttaactg ataaaaagga
    17041 tttagggatt cattcagaaa tgatttcaga tgggactttg gccctttatg aaaaaggtgt
    17101 tataaatggt aaatataaaa attttgataa agaaaaaatg acagttacct tcttaatggg
    17161 tactaaaaaa ttatatgact ttgcaaataa taaccctgca gtagaggtaa aaccagtaga
    17221 ctatgtgaat catccagcaa ttataatgaa acaacataag atggtttcta taaattctgc
    17281 tatacaagtt gatttaatgg gacaggtagt tgcagaggct atgggactta gacaatttag
    17341 tggtgttgga ggtcaagttg actttatacg tggagtgtct atgggtgaag atggaaaggc
    17401 aattatagct atgccttcaa taactacaaa aaaagatggt acagtaattt caaaaatcgt
    17461 atctattgtg gatgaaggtg cacctataac gacatcaaga aatgatgttg actatattgt
    17521 aacagaatac ggtatagcag aattaaaagg aaaatctctt agagaaagag caagaaattt
    17581 aataaatata gctcatccaa gtgtaagaga acatctagca gtagaatttg aaaagagatt
    17641 taaggagaaa tattaataat agaggggtgt taataatgga agcacttaga gtagttccaa
    17701 agatatttta ctttgataca tttaaagaat ttaatgaaga atttaaaata ggaaaaaatg
    17761 atttagtaat tactaatgag tttatatatg agccatatat gaaacctctt ggaatagata
    17821 caaatttaat ttttcaagaa aagtttggaa caggtgaacc atctgatgaa atgatagact
    17881 ccatgacaaa ggaaatgaag aaatacaatt ttgatagaat tattgcattt ggaggaggaa
    17941 caatagttga tatatgtaag atattagcac ttgatgttcc agaaaagtct attgatttat
    18001 ttgaaggaga agtatcacct aaaaaagtaa aagagttagt agtagttcct acaacatgtg
    18061 gtacaggtag tgaagtaaca aatgtagcta ttgcagagtt aaaatctaaa catactaaaa
    18121 aggggcttgc agtagaagaa acatatgcag actatgcagt gttaattcca gagacagtaa
    18181 aagggttacc ttacaaattc tttgttacaa gttcggtaga tgctcttata catgctattg
    18241 agtcttatct ttctccaaaa gcaagtccat ttacagagat gtattctcta caagcaataa
    18301 aaatgattat ggatgggtat aagaagatag ttgataaagg agaagaagag agatttaatc
    18361 atcttagaga ctttgtactt gcatcaaatt atgcaggaat tgcttttgga aatgctggtt
    18421 gtgcagcagt tcatgcacta tcttattcaa taggtggagc tttccatgtt gcacatggtg
    18481 aagcaaatta tcagttcttt actgaagtat ttaagatgta ttctagaaaa aaacctaatg
    18541 gaaaaattat aaaatgtaca aaaattttag cagatgccct tgaatgtgac cctaactgtg
    18601 atgtttatgg agaattagaa aagtttttaa ataaattaat agctaaaaaa gctttgagag
    18661 aatatggaat ggtggaaagt cagatagatg aatttacaga tagtacaata gcaaatcaac
    18721 aacgactact tgctaataat tatgtagagc ttagtagaga ggaaataaga gagatatttg
    18781 caaatcttta ttaatacaat tttttattta tatgtatagt caacataaac aatgctaatt
    18841 atatttatgt acaaataaaa ataagggaac ttaaatttta attaaagtta agttctctta
    18901 tttttatatg gagttaaata taagtatatt tttaatttaa aatatgctta tatttaagtc
    18961 tattacttta tttgaaacaa tttgtagaat ttcaaattcc ttgacagtaa taagtaagta
    19021 attgtataat caaactgcaa tatattaata atattagtga aaatgaaagg attataaaat
    19081 atgtataaat cagaaaattt ttcaaaaaaa tctgtattaa taaattcatt tttaagtaaa
    19141 tttttaaaaa taattggatg gggtttggta agcttattta cattatcagc cttagtactt
    19201 tcaactattt ccattataat tggatgggct gtaatacttc ctattcaagt atgtgcagta
    19261 tttttactta taggaggagt ttgtattttt aaaggtaaga gattaggaga ccaaatttct
    19321 cgttataaaa aatattgtac aattataaac aatagaaata ttattccagt agaacttatt
    19381 gcagaaaaca catctaaatc attaaatttt ataataaaag atgtacaaaa gatgatagac
    19441 aaaaactact ttataaatac ttatattgat aaaagaaata atcagattgt gttaacaaat
    19501 gaagattttg ttccaccaag atatgaagat gtagcatatg aagtcaaaga agaagaaaag
    19561 actgatgaat ccaatgaagt tgatacaatt ataaataaag gaatgaatta tctaacacaa
    19621 ataaaagaag ctaataaaaa tattaaatca gaatcaatgg gcgataaaat tgtacaagta
    19681 gaagatgtta caagtaaaat atttgatgtt gtaaaacatg acccatcaaa acttactcag
    19741 atacaaaaat ttatggatta ttatcttcca accactttaa aactattaaa ttcatatcat
    19801 acattggaag aacaaggaat tgatagagaa aatataacaa caactatgga aagtattgaa
    19861 aatacaatga atacgattgt agtagctttt gaaaatcaat tggactatct gtttgaagat
    19921 gaagccattg atatttctac agatattact gttttagaga atatgttagt ccaagaagga
    19981 ttaacgagtg gtaaatttta acttcaatag aaaaaatatt ctgttatttt taaacaatta
    20041 attagtcata aagtataaaa tgtgtattat ataagttaat cagtacttta tgaaggaaga
    20101 ggagagaaag atacaatgaa taatttagat gatataccag ttatgccaac tttgacactt
    20161 gacccatttg gagaagaatc aaacactaat gatatagata attctgactt attaatgaaa
    20221 aaggatgaaa aagacccaga agaagaaaaa ctgtctgaat ctgaacgcaa gatggtaaag
    20281 gaatttgcgg aaaaaataga tattacaaat acaaatatga ttttgcaata tggagctgga
    20341 gctcaaaaaa aggtagcaag tttttctgaa acagctttaa agagtgtaaa aacaagagat
    20401 ttaggagaag ttggagatat gcttacaaat ctagttactg atttaaaagc attttcagca
    20461 gatgaaaaag aacaaagtgg ttttttagga atttttaaaa aggcaaataa taaaatttca
    20521 aatttaaaaa ctaagtatga tagtgcagag gtaaatgtgg ataaagtaag caaagagctt
    20581 caaaagcatc aggttaaaat attgaaagat atagcaatgc ttgataagat gtatgaattg
    20641 aacttagctt actcaaaaga gcttactatg tatattatag caggaaaaca aaaattaaag
    20701 gatatgaaag aatatgaaat gccaaagttg agagaaaaag ctcgtttatc tggttcaaca
    20761 gaagatgctc aatctgtaaa tgatatggtt tcactttgtg acagatttga aaagaagatt
    20821 catgacttag aattaactag aatggtatcg cttcaaatgg ctcctcagat aagattggtt
    20881 caaaatagta ataatctgat ggcagaaaag attcaatcaa ctatagtaaa taccattcca
    20941 ttatggaaaa atcaaatagt gcttgctctt ggaatttctc acttaaatca agctatgaaa
    21001 gcacagcgtg aagttagtaa tatgacaaat gagcttttat taaagaatgc agaaactttg
    21061 aagatgggaa caatagaaac agcaaaagaa tcagaaagag gaattgtaga tatagacaca
    21121 attaagaaaa ctaatcaatc tctaatatct actattgatg aggtagttaa aatacaacat
    21181 gatggtagaa taaagagaca agaagcagaa gttgaattat caaaaataga aaatgaactt
    21241 aaaagtaagc ttcttgaatt tacagttaaa taaaaattat actaatataa aaagagactg
    21301 tctcaaaata gagataagtc tctttttcat tgtttaaatg attaaagtat atttatatta
    21361 taaatttcta ttatctttta acataacatc atgagctcca ccttcaacta tactagtaga
    21421 agatacaagt gtaagtttag catttttttg aagttcagga atgctaagtg ctccacagtt
    21481 acacatagta gaacgaactt tacttaaaga aagagttaca ttgtctttca aagaaccagc
    21541 ataaggcaca taagagtcaa caccttcttc aaaagaaagt ttcttatctc caccaaggtc
    21601 atatctttgc cagtttctag cacgagcaga accttctccc caatactctt tcatataact
    21661 accatttata ttaactttgt tagttggact ctcatcaaaa cgagagaagt atctaccaag
    21721 cattataaaa tctgcaccca tagctaaagc taaagttata tgatggtcat aaacgatacc
    21781 accatcagag caaattggaa tataaatacc tgttttttca aagtattcgt ctctagcttg
    21841 agcaacttca attatagaag tagcttgtcc acgtcctata cctttttgtt cacgagttat
    21901 acatatagaa ccaccaccaa taccaacttt aacgaagtca gcaccagctt cagctaggta
    21961 aaggaatcct tcgcggtcaa ctacatttcc agctcctacc ttaactgtat caccatattt
    22021 ttcacgaatg aaatcaagtg ttattttttg ccactcagaa aaaccttctg aagaatctat
    22081 acataaaaca tcagcaccag cttcaactaa agcaggaaca cgttcagcaa agtctctagt
    22141 attaatacca gctccaacta catatctctt agaagaatct aaaagttcaa gtggattttc
    22201 tttatgagaa gagtaatctt tacggaatac catatacata agattaccat tatcatcaag
    22261 tacaggaaga gaattaagtt tgtggtccca tataatattg tttgcttcct ttaaagtaac
    22321 atctttgtta gcataaacta tagatgacat aggagtcata aattcactaa ctttagtatc
    22381 taaatccata cgacttatac gataatcacg acttgcaaca atacccaata atttaccagt
    22441 tgaagttcca tcttcagtaa cagctactgt agaatgtcca gttttttctt ttaagtcaag
    22501 tatgtctttt aatgtgttat caggtttaat atttgaatca cttacaacaa aaccagcttt
    22561 gtgggattta acacgtgcta ccatagcagc ttcattttca atagtttgag aaccgtatat
    22621 aaatgaaata ccaccttctt tagcaagtgc aatagccatt ttgtcatcag aaacagattg
    22681 cataatagca gaagtcaaag gtatattcat ataaatatct gcttcctcgc cctttttaaa
    22741 tttagtaaca ggtgttttta aacttacatt agcaggtata caatcagtag aagagaaacc
    22801 tggtacaaga aggtattcac tgaaagtatg tgatggtgta tcaaaataaa acgccatttt
    22861 ttaatcactc cttatatttt tatacttttt ataattgata gtattaatta taacttattc
    22921 tttaatttta ttaaagtatt ttgtcaaata ttgagatttt tgaaaaattt aaactatttt
    22981 aattaaattt gtttaatata tattgcctta tagggtaaag ttgtatatta aataatgttt
    23041 agtgtttaat agtagctaat ttaaaattaa tctttagtga ttcatataat tacatttgta
    23101 tagtttacat tgataatatt actagagagt gcataaacct caaaaataca gataaattaa
    23161 atctatatta gtatatccaa aagtacattt aataaattta tttaactgaa ttattatttt
    23221 catttctatt aaatttaaat attttataaa aatagtatta tttacaaaat catatactcc
    23281 aaaatactac ataaataaaa ttaaacaaaa actaaaatga caaatgtcat tatctaaagt
    23341 gacatagaaa cggtttctta aagttgttac tataaaatat aaactctata ataaaagtat
    23401 aacaaaaggg aatcatatcg atatagaata taattcaaga ggaggtaaaa ttatgagtag
    23461 ttctaatcaa tcgacaataa agacatctat acagcgagta gggaaatttt taagtggtat
    23521 ggtaatgcca aatataggag cttttatagc atggggtctt ataacagcat tatttatacc
    23581 aacaggatgg atgcctaatg aaaaattgag tactataggt gacccaatga taaaatacct
    23641 tttaccacta ttgatagctt atactggtgg taaagcaata gcaggacaaa gaggtggcgt
    23701 aataggtgca gcagcagcta tgggagtaat tgttggtgca gatataccaa tgtttattgg
    23761 agcaatgata atgggaccat ttgcaggatg ggtaattaag aagtttgata aatttgtaga
    23821 tggaaagata ccaacaggat ttgaaatgtt agtaaataac ttttcaatag gtataatagg
    23881 tatgcttctt gcaatactag gattttatgc aattggacca gcaatagtag cagggacagc
    23941 tcttatagaa tctggagttc aatttatagt tagcaaaagt ttattgcctc tagtttcagt
    24001 atttatagaa cctggaaaag tattattctt aaacaatgca ataaatcatg gtatattagg
    24061 gcctataggt atagctgagg caaaagaagc aggtaaatct ataatgttct tactagaaag
    24121 taaccctgga ccaggtttag gagttctatt agcatattgg atgtttagta gaggaagtgt
    24181 aaaacaatca gcaccaggag ctgtaataat acatttcttt ggtggtatcc atgaaattta
    24241 cttcccatat attttaatga atccagtttt aatattggct acaatggcag gtggagcagc
    24301 aggaatattg actttttcaa tattaggagc tgggcttgta gcagcaccat caccaggaag
    24361 tatatttgca cttatggcac tagctccaaa gggaggatta cttccagtat tagcaggagt
    24421 tgcagtggca acagttgtat cattcttagt ggcagcacca tttgttaaga gagcttcagc
    24481 aaatcaaagt gaagaagaca gtacttcttt agaagaagct aaagcaaaaa tgagtgatat
    24541 gaaatctgca agtaagaact ctgagaaaaa tattgaggaa aaacagcttg aagtaaatga
    24601 gattaagaag attgtatttg catgtgatgc aggaatgggt tcgagtgcaa tgggagcttc
    24661 cagatttaaa aatagaataa aaaacttaga cttaaatata gaaattacaa attcatctgt
    24721 tgataatctt ccagatgata cacaaatagt agtaactcac aatacattag ttgaaagagt
    24781 tgctaagaat aattcaagtg ttgagatagt ttcaataaac aattttttaa atgacccaaa
    24841 tttagataca ttgtttaaaa gattagaatc taaataaaaa taaaaagtac cactaattag
    24901 gagtggataa tttgaaaaaa aagaagatta catctaggca aaaaaagata atactaatga
    24961 tagtagcaaa ttcaaagaaa aacattccaa taactatttc tgagattgca gggactttag
    25021 agttaagttc aagaactgta cttagagata tgtctggaat tgaaaaatgg tttgatgaaa
    25081 atgattttaa ctttgtaaaa aaaccaggag tgggattgat tttagaggaa aatatagaaa
    25141 atcaaaactt tataattgag ttgttagaag aagaaaaaat agaaaaagaa tacagcaagg
    25201 aagaaagaaa tttaattata ttatcaaagc tactagtttc taacgagcca gtaaaatcct
    25261 attattttgc aaaaatatta aaggtatctg aatgggtact gaataatgat tttgccttag
    25321 caagtaaatg gttggaaaga tttgatattg agcttgttag aaaaccaggg ctcggtgtct
    25381 acttaaaagg tcaagaaaaa aactttagag aggcatatgt aaatcttata tacgattcat
    25441 tcaatgaaaa agaaatacta gatatggtca gaaatataag tgaaaatata caaacagata
    25501 aagcaataga aattttaagt gaaaatagac ttttaaattt aatggacagg tgcataataa
    25561 gaaaagttga agctacatta acaaagaagc tttcagattt agatgtaaat ttagctgata
    25621 gtgcatatat agggcttgta gttcatattt cattagcctt acagaggata aaaaatggtg
    25681 aaaatataac tatggataaa gagtttctaa aagaattatc tataacagaa gagtttaaat
    25741 tagctaaaga aatcgtaaaa ggtatggaaa cagattttaa catggatata ccagtagatg
    25801 aggttggata tataactatg catataagag gtgcaaagca aaggtcatct tcaaaccata
    25861 aggctttaaa cttagatgat atagaaataa tggaaattac aaataagatg atagatttgg
    25921 cggaagatga atttaaaata agtttaaaaa atgacgagag gttatttaaa gacctagcaa
    25981 atcacttagg gccttctata aataggttga atatgggatt agaaataaga aatcctcttt
    26041 tagatgaaat aaaaagcaag tattcatatg cctatgatgt agttgaaaag atttctagaa
    26101 ttataaaaga taaactaaat ataaattcaa tacctgaatc agaaatagga tatattgcaa
    26161 tgcactttgc atcagccata gaaaaaaatc ttatgatgaa tactaatata aatattgttg
    26221 tggcatgtcc cactggaata ggtacttcaa gattcttatc aactaagatt gaaaataaat
    26281 ttcctaattt aaatatactt gaaaccatat cagctataaa catagatgaa gagtatttaa
    26341 aggaaaaaga tgttgattta atagtgtcta cagttgagtt aaatacaagt ttaaattata
    26401 tatgtgtagg tccatttatg agtttagatg atgaacagat aatcaaggaa aaaataaaat
    26461 ctatagctca aaataaatta atcaatttaa atgcgaaaaa tgatactaag agtaagaata
    26521 aagtatatga acagataaca gaaagtatga atataggaaa agatattctt caatttttag
    26581 aggaaattag atttgaaaaa tttgaaagta aagatttaag tgagcttatt gaagactcat
    26641 caaaaatatt tgcaaaatct agtgaagata taatctctat aaaagaatcg ttaaaagaaa
    26701 gattaaaaat ttcaattcca tatatagaag aatcaaaaat tctattgtta cattgtatga
    26761 gtgaaagaat agatattatg aagttatcaa taataaaact agagaataga atcgtgctag
    26821 attcaaatga agaaatcgac aatgtagttt ttatgttact tcctaaaaat tcaccaagtt
    26881 atcaaagaca aataatgagt gaaataagtg gttcattaat agacaatata atttttacta
    26941 ataagataaa taaattctct atagaagaga tggcattaga ggtaaaagat atagttttta
    27001 atttttatac aaacagatta aaagcattta tagataaata aaattaatat taaaaaggaa
    27061 ggttgatact atgagtaaag tattgaatga gaataatata tttttagggt tagatagtgt
    27121 ttcaaaggaa gaagctataa ctttagcagg aagaaaatta gttgaaaatg gatatgtaaa
    27181 agaagaatat ataccagcaa tgttagaaag agaaaaagta atgactacat atatgggaat
    27241 gggagttgct attccacatg gtgtaaatga agcaaaaaaa gaaatattat cttctggaat
    27301 agttatatta caattcccta atggtataga ttttgatgga gaaaaagcat atttattaat
    27361 aggaatagct ggtgttggag atgaacattt agaaatacta tctaatatag cagtagtttt
    27421 agatgatgac ttaacagaaa gactaaaaaa ttcaaatgac aaacaagctt ttatggaagc
    27481 ttttgccaac taatcttagg agggatttaa aatgaaaaag gcaattcagt ttggagcagg
    27541 aaatattgga agaggtttta ttggaggctt gttagttaag tcgggttatc atgtagtatt
    27601 tgctgatgta aatgaggaga tattaaactc aataaacaaa gataaaaagt atactataca
    27661 cataagagat gtagaatgta tagatgaagt aattgataat ataagtgcgg tttcatctat
    27721 aaaagaagaa ataatagatg agattgtaca ggctgaaata ataactacag cagttggacc
    27781 tttagttttg actaaaatag cctctacaat tgcaaaaggt ataaaggcta gaaaagaaaa
    27841 gggattaaca agtaatctaa atataatagc atgtgaaaat gcaatatacg caagttcttc
    27901 tttaaaagaa gaggtactta agtatttaaa taaggaagaa gtagaatatt tagagatgta
    27961 tgttggtttt ccaaactgtt cagttgatag aatagttcct cctggtaaaa acgaaaatcc
    28021 tcttgatgta acagttgaaa atttttatga gtggaatgtt gaaaaacaag gatttaaagg
    28081 ggaaatacca actatagttg gtatgaattt agctgataat cttatggctt atatagaacg
    28141 taaattgttt acactgaata caggtcatgc tataacagct tatataggat atttaaaagg
    28201 atataagact atagaagaga gtataaaaga taaatttatc tgtgatatag tcaaaagtgc
    28261 aatggtagaa agtggagaag gattgattaa aaaatacaat tttgactcag aagtgcacta
    28321 taaatatatt gataaaattt taaatagatt taaaaatcca tatcttaatg atgatgtatt
    28381 aagagtcgga agggaaccat taagaaaact aagtgataaa gatagattga ttaaaccttt
    28441 aatgacagca aaatcatatg gattatcagt tgataatttg attcttggaa taggtgcagc
    28501 gcttcattat aataatagtg aagatactca aagtgtagaa ttacaagagt tgataaagtc
    28561 tattggagta aaaaaagccg ttgctaaaat agctaatata agcaatgacg aagaactttt
    28621 aaacaatatc gaaaaaagtt atatatttat gaaaaattta taaatttact tgaaaaaaag
    28681 tagttctgat aaagtaacta taatatatta ttctacacag tttgaattat ttgttgaata
    28741 atagagaatt ataatatata attaaaagga ataaattaat atatttacct gtatatgttt
    28801 gataatatgg ttcaaatgtt tctactaagc taccattaat agcttgacta caggagtgaa
    28861 gaagatatag tttatactta ttttaaatta tatattaagt taattacttt gaattttaag
    28921 ctcctgtcta tgatatagac aggagctttt ttagtatttt aatataaaat acttacaaga
    28981 atagatagca aaattagaac aaatataatt tttttattaa tataatttta gaaagggcta
    29041 ggtggaagtt caatgaaggc tttacaagaa aagatattga gagaaggcag tgtttcagga
    29101 aatgatatac taaaagttga tagtttttta aaccatcaaa ttgatgtagc ttttttaaat
    29161 gaaataggaa gagaatttaa agagagattt aaaggagaaa aggtggataa gatatttaca
    29221 atagaggctt caggaatagc tatagcatca attgtttcac agtattttga taatgcacct
    29281 gtagtatttg caaaaaaatc agaatctaaa aatttggata aagatgtata tgaaactaat
    29341 gtatattcat ttactaaggc aagagagtat tcagttaaag tttctaaaaa gtacataaac
    29401 aaaggcgaaa atatattgat agtggatgat tttttggcaa atggaagagc tgctcttgga
    29461 cttaaagatt taattgagca agcagaagct aacttagttg gagtaggaat tgtcattgaa
    29521 aaaggatttc aagctggagg agcactttta aaggctaatg atgtaagatt agagtctttg
    29581 gcagtagttg aatctataga taatggaact gtaaaattta ggtaatttat gatattatat
    29641 acttgtgttt agcacatatt ttaactatgt aattatggag gattttttat gagatttttt
    29701 atagacacag ccaatattga agaaataaaa gaagcaaatg atttaggtgt aatctgtggt
    29761 gtaactacta atccgtctct aatagctaaa gaaggtagag attttataga ggtagttaaa
    29821 gaaataagtg aaatagtaga tggaccaata agtgcagaag taataagttt agaacataaa
    29881 ggtatgatag aggaagcaga aaaattatct aagatacata aaaatatagt tataaagata
    29941 cctatgacag cagaaggtct aaaagcggtg aaagtactat caagtaaagg tataaagact
    30001 aatgtaacgc ttatattctc tgctggacaa gctcttttag ctgctagagc tggagctaca
    30061 tatgtaagtc cttttgttgg tagattggat gatatatcac aaaatggtct tgatttaatt
    30121 gaagaaatcg ttgatatatt tagtgtaaat agtattgagg ctcaaataat agttgctagt
    30181 gttagaaatc caatacatgt tttacaagct gctagaatgg gagcagatat agcaacagtt
    30241 cctcttaaag ttataaacca aatgattaag catcctttga cagacaaagg aatagatagc
    30301 tttatgaagg attgggaagg tgcttcttta aaattataat tataaactac gctttataag
    30361 tatattaaag aggttattat ggaaattcta agtaataagg ctaggctatt ttgcctagtc
    30421 ttattttggt gtataatata ttgaaacata ttattgaaat agattaattt tttaagtgag
    30481 gaggcgaaaa atggataaaa tattaagaga gatacaaaga gaagataaaa aaaatccata
    30541 tactgaccaa gaacttgctg aaatgttaaa tgtagctagg tctgaagtga tatcagttag
    30601 gaaaaaaaat aatattttag attcgagaga aagaagaaaa aaaatattaa taaaagatat
    30661 atcaaaaatt gtaagtgaaa atcctcaaat gtctgaaaga aaaataactg aaatattaat
    30721 agaaaatgga tataatatat cgagaagtgc agtttcaaaa ttattaaaag aggaaaattt
    30781 aaatcagtca aagattggga ttaaggataa agacccagca tcatcaggaa agtatgtgaa
    30841 ggtgagtaaa gttgtagaag aagatggatt tgaagaattg ataggtataa agggaagttt
    30901 gaaagaaaag gtaaatctag ctaagtcagc aataatgtat cctcctaatg gccttcatac
    30961 tataatatat ggagaaacag gagtaggtaa aagtgaatta gctacatgta tgtataaata
    31021 tgctataaaa aacaacatta aagaagagaa cagcccattt atagtgttta actgtgcaga
    31081 ctatgcagaa aatcctaatc tattgatagc tcaactcttt ggggtagtaa aaggtgcata
    31141 tacaggagca gatgcaaata gagaaggtct tgtagaacaa gctaataatg gaatattgtt
    31201 tttagatgaa attcatagat tgcctgctgc tgggcaagaa atcttatttt cattaataga
    31261 tagaggagaa tttagaaggt taggagaaag tagttctaat agaaaggcaa atgttctcat
    31321 aataagtgct acaacagaaa atccagattc taatttactt caaacattta gaagacgtat
    31381 accaatggta ataaatttac ctaatatgag tgaaagacca aaatctgaaa gatatgaaat
    31441 aataataaag ttttttgaaa gagaagcaaa gcgagtaaac aagaatttta taataactaa
    31501 agaagttatg tgtgcactta tgaattataa gtgtactgga aatataggtc agttaaagag
    31561 tgatatacaa gtaacttgtg ctagagcttt tagtaaatcg atattttcta gcgataaagt
    31621 aattatagat ttagatagtt taagggatta tataaaaagt ggatattatg attgtaattg
    31681 taaaaatgaa aagtattctg agttttcagt tgaggatata tatatagata ttagtgaatt
    31741 ggtgagtgga aaaaatagaa ttttatctga taatgagata agcgagatat ataattatgc
    31801 agaaaaagag cttaaggttt tggaaagtaa gtgcttttca gaagaagagt taaaaaatgc
    31861 atttatagaa aagttagata agaagtttaa tgctattaaa aacaataaaa atttatctga
    31921 tagaagaagt cgaatagact ggggaggaca attaaaagag tctacactgg agataatgga
    31981 taaggtaatt gtatttatta aggagcagtt taagcatgta aatcaaggtc tgtacttggc
    32041 tctagcaatt catattgagc atgctatagg taggataaaa gatggaaaaa ctataataaa
    32101 tccgagttta gataaaataa aagcatcaat gccaatggaa tatgagttgt caagatatat
    32161 aatgggtata gtagaagatt tgacacaagt aacatttcca gaagatgagc ttggatattt
    32221 ggcttattat ataaataaat tttgttataa tgaggaaagt ataaaagata aagttaaagt
    32281 agtaatagtt acgcatggta aagttggaat tgaaatgtct aaagttgtaa atcatatttt
    32341 aggtatagaa tgtacactag gtatagaaat agcacttaca gattcaccat cagaggggat
    32401 agagcatgta ttagaagaac ttcaaaagat agaagctaga aaaggtattc tagttctaat
    32461 tgatatgggt tctttggtaa ttcttggtga tgaggttgaa aaaaggcttg gaattagatg
    32521 taaaactgta aatagagtag atacattatt ggcaatggaa gcaggaaaac ttgcaacaat
    32581 tgaaggaaaa agtttagatg gtataatagc tgatttaaag aaaaataaga attatgctat
    32641 gataaataca aataaattta gttacagaaa aaacgagtat ggaaagaaaa atgtaatcat
    32701 tactttatgt ttgagtggtg taggtacagc tttaaattta aaagagcata tagaaaaaca
    32761 aattaaggaa tatgacactt taattgaagt aaagccagtt gcttttttaa ataataattt
    32821 agaagaagag ttaaatgata ttgaatctga atataatatt attgctatct gtggaactat
    32881 tgatatagat tataaaaacg tgccttttat ttcttataat gaggtacttg gtaaaaatgg
    32941 tattaataaa gtattagagc atttaaatag taaacaacca gctttaaata ttgaaaacca
    33001 gttgaataat ttaatacatg aagatttgat tttatacaat tttgaaggaa tttcaaagga
    33061 gtatataatt gatactcttg tttcaaaact tgaagaaggt ggatatgttg actcaaagta
    33121 tatattaagt gtatataaaa gagaagcaat gggaagtgtt gtaatggcct ctaaggtagc
    33181 cgtgccacat ggacttccag aaaacgttat gaagcctgca atagcaatcg cgaggttgaa
    33241 taaacctata gtatgggaca ataaatttat ggtggatttg gtggtactac tggcacttaa
    33301 agaaaataat aagaaagaaa tacgaagctt attttcaaag attaatgacc agcatacttt
    33361 agaagtttta ttaaatactg aagataaaaa tgaaataaaa gaacttttaa gctaattatt
    33421 agtaccgaga agaaagacaa aaaaatttgc tttagtataa aatttaaaac tactcaattg
    33481 ctaagtagtt aattactcta tataaggcta gttctatgaa atttatttat atgattttat
    33541 agaattagct tttttcttgg taaataaaat atataaattt atttatgtaa aaagtaa
//
LOCUS       DAEHWO010000042        33433 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEHWO010000042 DAEHWO010000000
VERSION     DAEHWO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.042"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(467..1339)
                     /locus_tag="KNP54_002289"
     CDS             complement(467..1339)
                     /locus_tag="KNP54_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0893187.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1733..2311)
                     /locus_tag="KNP54_002290"
     CDS             complement(1733..2311)
                     /locus_tag="KNP54_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBF0893188.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2369..3085)
                     /locus_tag="KNP54_002291"
     CDS             complement(2369..3085)
                     /locus_tag="KNP54_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBF0893189.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3276..4361
                     /locus_tag="KNP54_002292"
     CDS             3276..4361
                     /locus_tag="KNP54_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBF0893190.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4516..5175)
                     /locus_tag="KNP54_002293"
     CDS             complement(4516..5175)
                     /locus_tag="KNP54_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBF0893191.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5392..6684)
                     /gene="lysA"
                     /locus_tag="KNP54_002294"
     CDS             complement(5392..6684)
                     /gene="lysA"
                     /locus_tag="KNP54_002294"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBF0893192.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6702..7895)
                     /locus_tag="KNP54_002295"
     CDS             complement(6702..7895)
                     /locus_tag="KNP54_002295"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBF0893193.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHLVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(8256..8873)
                     /locus_tag="KNP54_002296"
     CDS             complement(8256..8873)
                     /locus_tag="KNP54_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893194.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9043..10743)
                     /locus_tag="KNP54_002297"
     CDS             complement(9043..10743)
                     /locus_tag="KNP54_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893195.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(11140..11703)
                     /locus_tag="KNP54_002298"
     CDS             complement(11140..11703)
                     /locus_tag="KNP54_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893196.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11862..12575)
                     /locus_tag="KNP54_002299"
     CDS             complement(11862..12575)
                     /locus_tag="KNP54_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBF0893197.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12867..14531
                     /locus_tag="KNP54_002300"
     CDS             12867..14531
                     /locus_tag="KNP54_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBF0893198.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLKQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14638..15537)
                     /locus_tag="KNP54_002301"
     CDS             complement(14638..15537)
                     /locus_tag="KNP54_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBF0893199.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15564..16202)
                     /locus_tag="KNP54_002302"
     CDS             complement(15564..16202)
                     /locus_tag="KNP54_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBF0893200.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16539..17537)
                     /locus_tag="KNP54_002303"
     CDS             complement(16539..17537)
                     /locus_tag="KNP54_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBF0893201.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17635..18210)
                     /locus_tag="KNP54_002304"
     CDS             complement(17635..18210)
                     /locus_tag="KNP54_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893202.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            18526..18789
                     /locus_tag="KNP54_002305"
     CDS             18526..18789
                     /locus_tag="KNP54_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893203.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(19226..19598)
                     /locus_tag="KNP54_002306"
                     /pseudo
     CDS             complement(19226..19598)
                     /locus_tag="KNP54_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            19939..21051
                     /locus_tag="KNP54_002307"
     CDS             19939..21051
                     /locus_tag="KNP54_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0893204.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(21259..21735)
                     /locus_tag="KNP54_002308"
     CDS             complement(21259..21735)
                     /locus_tag="KNP54_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893205.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(21934..23559)
                     /locus_tag="KNP54_002309"
     CDS             complement(21934..23559)
                     /locus_tag="KNP54_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0893206.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALLNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(23897..24916)
                     /locus_tag="KNP54_002310"
     CDS             complement(23897..24916)
                     /locus_tag="KNP54_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBF0893207.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(24913..25482)
                     /gene="mocA"
                     /locus_tag="KNP54_002311"
     CDS             complement(24913..25482)
                     /gene="mocA"
                     /locus_tag="KNP54_002311"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBF0893208.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(25589..26311)
                     /gene="yqeC"
                     /locus_tag="KNP54_002312"
     CDS             complement(25589..26311)
                     /gene="yqeC"
                     /locus_tag="KNP54_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBF0893209.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRNKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHRTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(26494..27771)
                     /locus_tag="KNP54_002313"
     CDS             complement(26494..27771)
                     /locus_tag="KNP54_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBF0893210.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASFNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(27910..30216)
                     /locus_tag="KNP54_002314"
     CDS             complement(27910..30216)
                     /locus_tag="KNP54_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBF0893211.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKILSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(30209..31003)
                     /locus_tag="KNP54_002315"
     CDS             complement(30209..31003)
                     /locus_tag="KNP54_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBF0893212.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(31110..32468)
                     /locus_tag="KNP54_002316"
     CDS             complement(31110..32468)
                     /locus_tag="KNP54_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBF0893213.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
BASE COUNT        10958 a         5669 c         3496 g        13310 t
ORIGIN      
        1 ttctaaaaaa gtttcccttt ccccaaaaat ggctacttaa aaaatcaaga tttcatacct
       61 aactactaat tctatgattt ttaaattttt caacttcttt gtcaaagtta aaataaaata
      121 ctaaaagaca catattatag tgaacaaaaa agatagaaat acatatttta atataatttt
      181 aataagatat tatatactta aatacaaata aaattaattt tataattgtt aattaaggaa
      241 atgatattgt ttagagaaat aaaaaaagca ctctccatga atggaaatgc tttctttaat
      301 aaattagttg acgtagtaaa gatgtattca gaatacatct ttatgttttg agtctcgaaa
      361 tatttatttg tattatttaa acgaaaattt attttttaag tgataatcga gtatttacta
      421 ataaggctat gattctcaat ttcatagcct tattaatata caaactttac tcatacacag
      481 aatatctttt ccaaatttgc tctaaatcat caaaatgctg tttaatatct tctttttcct
      541 tcatcccaac agatatagca agggcatttg aaatactaag agctggaact agagaatcta
      601 caaatgaagc catattactc ttaactagaa gagtgttatc tgcaagtgat gctactggcg
      661 caaataagct atctgttaat gatattacat gggctccttt ttctttagca taattgacaa
      721 tttgataaga tttcttagaa taacgaggga aactaatagc aactattaca tcttcttcat
      781 ttattcttac aatctgctca aaagcatctc ccatatccat tctaattata tgaacattgt
      841 caagtattat atctaagtaa aaacctaaat attgagctac tacaaaagaa ctcctcattc
      901 caagtatata tatttttctc gctcttaaaa gtttgttaga agcttcttta aacgctctct
      961 cgtcaatttc ttctagtgta gaccttatat tatctatatc actttttaaa actttgttta
     1021 gtattgcaaa atcatcggaa taatcatgtg ccatttcaac tctttgtact gtagttagtt
     1081 tattttttat gagttcttga agtgcagctt gtaatttagg atatccacta taacctaatg
     1141 catttgcaaa tcttacaact gtagactcac ttactcctac ggtttcaccc aatttacatg
     1201 cagtcataaa tgcaacttta tcataattat ttaaaatgta ttgtgctata agtttttgac
     1261 ccttactcaa tctcgtatat tgagattgta tatttgatat caaatgttta ctgtccttca
     1321 tttcatttgt ttcttccatt tttttctcct tttagttata taaactattt tgttttatta
     1381 acactgtctt tttctctaaa aattttattt tttatctcaa tttcatctta gtttttatca
     1441 tagcttctta aactcataaa attctaactt ttctgtacct tatacttcac atagtatttt
     1501 cgattaaatt tattatacca tctttccttg cattttttaa tatttatcca atatttcttt
     1561 taaatttttc aatttttact catttaaaag ttatctatct tattttgcat atttagatgt
     1621 atattttgtt ttgagaataa actgttgtat acttattatt taaagtattt ttaataggtc
     1681 acactatata tattaactct taatacaatc ttgtcaagtt ttttagtatt tattatgctt
     1741 ttttcttttc aattaaaatc aattgtggtg ggttattgac ttgatttaaa aacttagatt
     1801 ctaaaacatt aaattcatct tgatttaaat tattgacaag gttatatatg caatcttttt
     1861 cttcttgacc tccatcatgc cctgtatata tggcaatgct tattactcca ttttctttta
     1921 acatttctaa acttaacttt atagccttta aagttgtatc tggtttggtt ataattgaat
     1981 gtttcgctct tggaagataa cccaaattaa ataaaacaca tgaaacttct tcttttatat
     2041 attgattcat tttttcatgc ccatcaaata tcaattttac tctatctgta tatccttctt
     2101 tctctagttt ctttcttgta gactttattg cttcttcttg tatatcaaaa gcatatacaa
     2161 agcccttttc tccaaccttc tcagctagat accttgtatc atacccattt cccatagtag
     2221 catcaattac tatgtcacct tcatttataa tattttctaa ataaaattta tttatatctg
     2281 taattttagt taaatacttt gcatatgcca taatactatt tctccctact attaacttta
     2341 tttcattttt tctcaattta tttttatctt attttattga ttttaaatat tttatttcat
     2401 cttctgttag gtatctatat tctccaactt tggtgtcttt taatactatt ttccccacag
     2461 aaatccttct taaatttaaa actggatgat ttatagcttt gcacattttt cttacttgtc
     2521 tatttctacc ctcatgtata gttatttcac acactgaata atttttttct ttattttctt
     2581 tagttaccct tattttggca ggtgccgttg tgtaatcttc tatttttagt cctgtttcga
     2641 attgtcttat ctcatcatca cttataattc ccttcacact tgccacatac attttatcaa
     2701 tttcatgctt tggatgggta agcttatatg ttaaatcgcc atcattagta agtattaata
     2761 aaccactagt ttcataatct aatctcccta ttggatatac tctttccctt acatctttaa
     2821 gtatgtctat tacactgggt ctattgaatt ggtcttttac tgtagttata tatccctctg
     2881 gtttatttaa tactatatat atataatttt cacttggttt tactttttta ttatcaaatt
     2941 ctactatgtc tttttcttca tcaatattaa aagataactc ttttactaca cttccattta
     3001 cctttattct tcctccaaga attatttctt ctgcttttct tcttgatgct attccacaag
     3061 aagctatata cttattaatt ctcatactta atccttcctt atcttaaatt atgtgtgttt
     3121 aatattttta tcaatgttaa ttttgctaca ttattatact atactagacc ttaattaaaa
     3181 acaagcaaaa aaattattta attttcctaa ataattgtaa tttcttttca catactatta
     3241 atatgtaata gctgactaaa cactatttta aggaagtgat tattatttca aaggaaaata
     3301 taaaatatta tttaatagtc gtgtttattg gaattttatt ttttaaattt attaatactc
     3361 catcagactt tatatctagt attgaaggat tcttaaagtt ttttagccca tttttattag
     3421 ctattttact tgctttactt ttaaatccac ttgtgatgct ttttgagata aaattcaaag
     3481 cacatagact tttagccatt tttttatctt atatatttat aggttttatt ttagcctttg
     3541 ccattaggtt attaattcca tcaatagcta atacattaaa tagattgata aatgaaatgc
     3601 ctatgtatac tgattatata gatagtttta tagaaaaaaa tatgtcaaac atatattttc
     3661 taaaaacttt aattcctcat atacaacata gtttagataa tttattaaaa gaagcaagta
     3721 attttgttgg taaaattcct aaaaacttct taatctatac acttagtata tcttctatgc
     3781 tatttaatat gacaatggga tttatactat ctatatacat tatatatgac aaagaaaaaa
     3841 ttgcattggg atttaagaga tttctatatt cttctactgc tagaaacaag gcagataaca
     3901 ttatagaatt ttttaggact actcatgata ttttctatga ttatttactt ggtagaatat
     3961 tagactctct tattattggt ataattgcat ttttaggatt tcaatttgtt atcagaatag
     4021 aaaatgcttt atttttagct tcaataatat tcttaggtaa tataattccc tattttggtc
     4081 cttttattgg tgcaatccct ccaatagcca tgactatatt atatagtcca caaaaaacta
     4141 tatgggtcat tgcatttcta tttatattgc aacaattaga tggaaatttt atagaaccaa
     4201 aagttatggg taatcaagtt ggtataggag ctatatgggt aatatctgct attttggtgg
     4261 gacaatctct atttggtttc ataggagttt ttctttcagt accaatagct gctgttgtaa
     4321 aaacttatgt tgataaatat atagataatc gtttacaata gattatctct actgtgactt
     4381 taatttttag tttaaaattt aactgctatt tattaaatta tttctcaaaa aatatctctt
     4441 agtaagaaaa aattgctaag agatattttt tataatatat aatttgttca ttaaatttat
     4501 gcatatattt tatacttatt gattatttga gttttgagaa tttccaccac tatctgaacc
     4561 accagtagta tcttgtggag ttggtgctgg tgttggatta ctattatttg gcttttcttg
     4621 attttgagaa gaactgttat tattgtcaga cttattacta tctgattttt tatcattgtt
     4681 tttagaacta gatttattat ttttactact tccactataa gaagatttcc ttgcatctga
     4741 ttcaactcta tacctatctt ctccagccgt atcttttgcc tttttctttc tttgttcctc
     4801 tgcttcgttt tgttcttttt ctaatttagt taactcttct ttctttttag ttgcctcttc
     4861 tttaataaca gaggaaccat ttttgatttt ctctataagt ttaagttcct tgattgcacc
     4921 ctcataattt tttaattctt caaactccgt catatttgac attctcatag cttgcatata
     4981 catagctctt gcattctcat tagtactatc ttcttccagt gcagaggata atgattccat
     5041 agctttttta tagttatgtt tttctaaata tgtttttcct tgctctacta aatttatttc
     5101 atctttttta ttaaatgaac atcctacaag aaatatagat aatatcgata ttaataaaat
     5161 tactcttcct ctcattaaat ccctccttgt catatacttt aaattttatc ataattataa
     5221 agtttttaaa atattttata tttattacaa gaaatttgtt agtaaaacaa aaaataagca
     5281 gatatgctac gaacgataca ataaaccaaa aattaattta gagatacata tcctagcaaa
     5341 tctgctcata ataaacttta atatttaatt tttattatat acttctctat tttatatctc
     5401 taaagctaat aagtcctcat agctttgtct cttacaaatt atcttatcat ttccatcaaa
     5461 tactgatacc actgctgctc ttggtatttt attataattt gaagacattg aatatccata
     5521 tgcaccagtt gatgttgtta taagtatatc tccactttta atatccatta tgtttatatc
     5581 tccaattaat atatctccac tctcacaaca ttttccagct attgttacat gattcatagc
     5641 ctcatgatta attttattca caatactaca ctcataacta gcttggtaca acgaaggtct
     5701 tacattatct gtcatacctc catctacact tacataaacc ctaacatctt ttatatcttt
     5761 tatagaacct actgtataca atgtacttcc tgcatttgca actattgacc ttcctggttc
     5821 tattaccaat gtaggtactt ctattccaag ctctttacat gaagtttctg ctttagtgat
     5881 tatggtttca caaaactctt ttatagtttt aggtttatct ccttcgctat aataaacgcc
     5941 aactcctcca cctaggtcaa tttctgttag ttgtatgttg aatttttctt ttatttcttt
     6001 taccaagttc atcattatat ccactgtatc tatgtatggt tctacatcaa atatttgtga
     6061 acctatatga gcgtgaagac ctacaagttt aatattttta tattcactta atttttctat
     6121 tgctctaaat aaatctccat ttactaaagc aaatccaaat ttagaatcta tctgtccagt
     6181 ttttatataa tcatgtgtat gagcttctat accaggagtt attctaaagt atatctcttg
     6241 agttttacct ttatcttcac ataatgcttc aagcaaatct aattcataaa aattatccac
     6301 tacaaattta cctacaccta aatctaatcc catgtttatt tcttctttag tcttattgtt
     6361 tccatgaaag aaaacttttt ccataggaaa atttgattta taagctgtat ataactcgcc
     6421 tcctgaaact acatctaaac acatttgttc ttcatttata agattacaca tgtaaagagg
     6481 taaaaaagct ttccctgcat aagcaacctt attttttccc tctctagcct taaaatattc
     6541 tatatattct ctacaatttt gtctaactaa agcttcatca aatacataaa gtggagtttg
     6601 atatttttta ctaagttcta aacaactcac tcctccaata tataattcat cattatttac
     6661 agtcatagtt ccatgaagtt tcataatagc ctccccaaat tttatatatt aaatacttct
     6721 gctatttttt ctatagctac ttgcttatca tcagaattta tagcacaagt tatacgaatc
     6781 tctgatgtag ttataagttt tatcattata ccattttcat tgaatatctt aaatacttta
     6841 gcagcaactc cagaagtatt tttcatacca agacctacta aagaaaattt agtgatatta
     6901 ttatcaatca ctaaatgttc ttcatctgta tatttagata ctatcttttt acattctccc
     6961 aactcttctt ttggaactgt aaatgataca cttatcttat ctaaaatagg tgcagtttgg
     7021 cttatcatat ctacacttat acctatagtt gctatatctt caaataagct agatatattt
     7081 tcagctttaa aatcttttat tgttatagaa ctgtcatcat cactagtagc taatcctgtt
     7141 attactttat cctctaattt catgtctttt ccccctctta tatatgttcc tttttctgta
     7201 ccacatgtac gtccgacata gatttcaaca ccatattttt gtgcaagctc tatacttctt
     7261 gaatgcatta cttgtgctcc taaactcgct aactcaagca tttcttcata ttcaatctca
     7321 tcaagtttac tagcctttga atattttctt gggtctgtaa aataaattcc atcaacatct
     7381 gtatatatct cacattttcc atttaattta accgcaagag ctacagcaga tgtatctgaa
     7441 ccacctcttc caagagtggt tacatcacca tcttcgttga ttccctgaaa tccagttact
     7501 atcacgacat ttccttcatc taaactattt ttaattctgt ttacgtttat atcatcaatt
     7561 tgagactttc catgaagacc actcgttttt atatttaact ggtaagcatt ataacttata
     7621 gctttacatc caagtgcatt taatgctatt gataataaag atgctgaaat catttcacca
     7681 gtagacatta aagcatctaa ttccctctta ctaggttcat tactcaattc ctttgctaaa
     7741 gttatatatt catcagtgga ttttcccatg gcagatacaa ctattaccat ttgtggattt
     7801 tcttttcttc gttctattat attttctgct attgatttta ttttttcagt atctgctact
     7861 gaacttccac catatttttg aacaattata ctcatgcttt ctccccctca agctaaattt
     7921 tgataaataa aaacgcccaa aggtatactt tggacgtgta aatttcatag accaagtaac
     7981 cttgtagctc accactttaa aagtgacagc cttatgcata ttctgcataa gtccagaaaa
     8041 tttgtccgtc aacaaaattt cttcggctat ataccctttc atcaattatc aacgcttacc
     8101 agctcctatt gaatactatt gaatacagct acctctaccc taggctcatt atttttaatt
     8161 aatttattaa tatagtttta tcatattcta tataatattg caacaattat tttacaaaat
     8221 gtggcaaatc gatagttttc ttttctaaag ttagcttata tacaattaaa tagtttattt
     8281 aatcctaaat ctataaaatt tatgctatac tcattatcat atctctctaa atcatttaat
     8341 tcggatagat tatctggtgt aactaccaaa acgtttggta ctttaaaaaa tggaattgta
     8401 gatttatcta tttttttaga aagattttcg tatttagaaa tgtctatttc attatttaag
     8461 tcaacatcaa ctaaaacttg ctttatatta ccaaattggt ctgtatattc aataaataaa
     8521 tcgtatttca catcatctac actaacattt cggtaaaatc tttttacatc acaacctgca
     8581 gtattgattc taacaactaa ttctgatcct actagagcct ttattaaatc atctccctta
     8641 aaaagtttac taccgtttaa atagtataca taagagaggt ctttataatt ataataatcc
     8701 acatcacaag gatatttttt tagtgtatat tcactacaca tttttctcaa agttttttta
     8761 aaattttttt tattgtatct tttttggtct ccataaattt ttctaaattg agactctgta
     8821 acacatctaa ccctgctaat taaaagtaat atctcttttt ccatattcgt catagtacat
     8881 tctccttgaa gtattatttg caaagttgta ctaatattat attaatttta tgacattaaa
     8941 tttacaaaga attaaaataa aatagctaat ttttatagaa ttaaattcta taaaaattag
     9001 ctatcactat gttaaatact attatcaatc tttttattta aattatacat taccttgatt
     9061 ttcagaatct ttggaatctg tattttcatc agttcctgtt ttttcttttg cttttttatc
     9121 ttcaaagttt gcaatattta ggttatcaaa ttctgacatt tctattacac cagattcttc
     9181 ttttgaatac gatattttga ctttatcacc aacctgagtc aatggcaatt cgctagatac
     9241 ttttgaagta gccctaaata ttatatcttt atttgaatct aaagttacat aataattagt
     9301 gttaccacct cgcacatctg ggcttattct tgtcactgtg ccttctaata cctcatcttt
     9361 taaatcatta tcaagtttta aatcattacc cttagattct aatgcatcct tatagtttct
     9421 taatgcttca ttcttatctt cacctattcc aagtacatta taatcttcaa cagatacaaa
     9481 tgcaactctc ttaacaagac ccgccttatc ttttaatgat gatacatatg ttggctgacc
     9541 caatatatta tacattacag ggaacgtcgc ttcataattt ttttcttgaa cattaccttc
     9601 agctgatttc attgcagccg tttcagtagc tcctggttgt ttatataatc tagcttcttt
     9661 tgttctagaa tcaactaaca taaatccaat tgtagattca tctccacctg aagatgttat
     9721 acctgtatac caataagacc tgttatcatt gccataaact aatgatgtac cttctgttgg
     9781 tactaaaact cccttttctg atataacaga gtttaaaaat ccattaacat aaacacccca
     9841 gtctttaatt tggtctgtta caaagctttg tggttgtatt ctatccaccc atttaggcgt
     9901 gtttttaaca tcataaacat ttatttttcc agtttctgca tcaacagtgg ctattcctgt
     9961 tgcatttgct cctccatagc caattttatg ttcatataaa cttacaaccc aataaggtct
    10021 tccttcatca tttatttcaa gagtgaaatc tgtcatacca acatttacaa taccatgtat
    10081 gtataaatgt ctttgtaaat cctgatgtaa gtaggcttct ggttggtaaa ctatctttat
    10141 tggctttcca tctatttctt gaactaattg gacgtcttga ggattactag ctgatacttt
    10201 tacataacca cttgtaccac ttagagatgt tatccattta attatgtctc tgtgaacaag
    10261 aggcgctacc cagtacaact ctccatctac attttgtata tgaaattttc ctaatttgga
    10321 tacactccct attgcaggaa cttctccaag ctttttgtca cctaatttca ttgccatatc
    10381 ttcatctaca agacgaatgt catttacact gacagggcta atgtcatcag taaatttact
    10441 ttcagttact tttcccaata gttctctata tgattttgca tgaagtacag gtgtagaagt
    10501 tataaaggga actactacaa tatacacaag caaagctatt gctattgaaa aattatattt
    10561 agccatttta gatgctcttt catttctatc taacatcata tctagtattc ctgctacaac
    10621 aaagaaaatt attcctactg aaaataaaga tgtaaaatct aatcttagta caggtaattt
    10681 aataaatgca taaattatta caattattaa tgcaactcca tatgttttaa gatatcgttt
    10741 catttaatac tcctctctaa aaaatgttat tattactatt atatccatat atttacaaaa
    10801 aataaatatt tatcatattt attatatatt aagatatctt tatatattta tagttctgct
    10861 tattcaacta tatttaacat tatacgtgta tgtataaata ctttttatac actgtttgtg
    10921 ctatccatcc cgcacctaaa ggagtgggat ttttgcacta ttctgtatta tatatatcca
    10981 aaaatgttat aaaaatacaa atattagcag aaatttaaaa actgaagaaa gtattctaac
    11041 taagatttac aaattcttaa tcctatcgaa gttaaactac tatcttcagc ctaattatct
    11101 agcaatattt ttttatatga aaaactctaa atcaagtttt taaatgtttg cgatttttga
    11161 tacataagaa tgttgtctag aattatattc tgataataaa ccttcatact ctaaggttaa
    11221 gccagataaa ttataaaaat catttggcgt tacttcaaat gcttgtttat ttaaaatgtc
    11281 tatctcactt ttttctaaca tgtcagcaac aaaatttgaa catacatatt tatattcaga
    11341 ttgtctctga atattcatta gtaaatatat taatgccatt gtatcgtaat agtaatcttc
    11401 tctataatca ctaattaatt ttatattttt atatagattt tcatattgta aattatctac
    11461 ttctaacgaa tataccctac acacagtgtt ttttcttata gcatataatc cttgatttat
    11521 attttcttca acaaatcctc caataaatgg attccttgga tttagccttc caaaagaata
    11581 cattggtttt agattttcat ttaatgatat tgacacatgt gtatacagct ttttacttat
    11641 attccttatt aagtaagata atatagttcc tgtatatgtt gttacaatat agactttatt
    11701 catcatttcc ccccaatcta gtaactaaat aatattatac acttacaatt taatatcata
    11761 agatattcta acataataaa tgtggtttta caaattttga ttttaaggta ctttaatatt
    11821 atataatata ataaaaatat aaatataagt tttctatatt tttaaccaac agatgttttc
    11881 ttcaaattaa tcagatgatt tagtatatct tgaacctttc cagagtcctt taaatatcct
    11941 aatgccccat ttatttgtga ttttaaatct atttctactt ccatatccaa atcaacattt
    12001 ccttttttta tagatatatt tttaagtgtt attgggtaaa gataactttt ttccaaagta
    12061 atcttatttc cattaacctc aaatggaact tttttattgt agttacttaa tattttttct
    12121 agcattttat cacttagttt aaattttcca attttcacat tctcaagact tacaactaag
    12181 tttccatcct ttaaagtagg tctcaattca agttcatatt gactatttac caaaccaaat
    12241 accttatatg gtcctgctac ctttatttta ccatttttca tttcaacaaa attattttca
    12301 agttcattaa ttccatgctt ctgcatcaat gtatatatta aatttttaaa ctcttcctct
    12361 gaaacagata tttttccaac cattctaagt ggatttttta ctacctccat agaatttata
    12421 tatgagcctt ttgataaata ttcttcatct atgattttat tattttgtga actaacatca
    12481 tatctttctt ttggtgtcaa gatatataca acaattcctg caagtactaa aacaataaca
    12541 attaaactta acaaaatctt tgcaaccttt cccataatcg tctcctttac aaatctgtca
    12601 tcagatttaa aataaattta gataactaac ttcacataat attcttaaca atatacatac
    12661 tataatacag tcttttaaaa attaattcaa ccaatctaat gttttgtaaa taaactgtaa
    12721 aaacatgttt ttagtataaa agttaatatt ttgcataata ctcttaatta cacctttatt
    12781 tttttctaat cttggattaa aattaatatt atgcaataca gtgtagtgtt ctgtattata
    12841 atcaaattaa ataggaggta tagaatatgt caaatgaaac gaactcatct aactttataa
    12901 agaatattat tataaacgac ttagaaacag gaaaacatga cagtatcata actcgttttc
    12961 cacctgagcc aaacggatat ttacatattg gtcatgcaaa aagtatatgt cttaattttg
    13021 gattagctaa ggagtttaat ggaaaagcta atttaagatt tgatgataca aacccattaa
    13081 aagaggatgt tgaatatgta gagtccataa aagaagatgt aaagtggtta ggatttgatt
    13141 ggaacgagtt aaattttgca tctaactact ttgatgaaat gtataagaga gctttaatac
    13201 taataaaaaa gggtaaagct tatgtatgtg atttgacaca agaggaaatg agagaatatc
    13261 gtggtactct aactgaacca ggaaaagaaa gtcctcatag aaacagaact attgaagaaa
    13321 accttgattt atttgaaaga atgaaaaatg gtgaatttaa agatggtgaa aaaacattaa
    13381 gagccaaaat agatatgtct tctccaaata taaaccttag agacccaatt atatatagaa
    13441 tatctcattc aacacaccat aatacaggag ataaatggtg catatatcct atgtatgctt
    13501 ttgctcatcc aattgaagat gcaattgaag gaataactca ctctatatgt actttagagt
    13561 ttgaagacca aagacctctt tatgattggt ttgttaaaga atgtgagatg gaaaatatac
    13621 ctagacaaat agaatttgct agacttaata taaataatac tgtcatgagt aaaaggaaat
    13681 taaaacaact tgtagatgag ggtattgttg atggttggga tgaccctcgt gttcctacaa
    13741 tatccggaat cagacgtaag ggatatactg cagaagcatt gcgcaatttc tgtagtgaaa
    13801 taggggtatc aaaagttaac tctacggtag atagtcaaat gcttgattat ttcctaagag
    13861 aaaacttaca accaaaggct cctcttacta tgggagtttt aagaccttta aaacttatta
    13921 taactaatta cccagaagat aagattgaga tgcttgaaat agagaataat gctaaagatg
    13981 aatctcaagg aaagagatta gttcctttct ctagagaatt gtatatagaa caagatgatt
    14041 ttatggaaga acctgttaag aaatatttta gatttttccc aggaaatgaa gtccgtttaa
    14101 aaggtgctta ttttgtaaaa tgtactgatg taattaagga tgaaaatgga aatgtagttg
    14161 aaatacatgg tacttatgac cctgaaacta agagtggctc tggctttaca ggacgtaagg
    14221 taaaatctac aatacattgg gttgatgcta aatcagctat accatgtgaa tttagattat
    14281 ttgaaccatt aattcttgat gatatacctg aaaatgaagg taaacatttc ttaaaacaaa
    14341 taaatcctaa ttcattggaa atattacaag gttttgttga acctacacag ataaaagatg
    14401 ctaaaccttt tgataaattc caatttgtta gaaatggatt ctttagtata gataataaat
    14461 atacaactga tgaaaaattt gtatttaata gaatagttcc tctaaaaagt tcttttaaac
    14521 caggtaaata atcttacaat caaaaaatga agacttaaaa tataaattac ttctactata
    14581 aataaactta gttagaagta attttttatt tgagtcttca tcatttactt taaatgatta
    14641 acttttttca ctacagattc ccatgacttc tattccatct tttatgcatt ctatgttaag
    14701 aggaaaatct ggtccttttt ctccgtcaat atctgttata agtgaatctt cacattctat
    14761 atgcaccttt ttagttttaa agtatagtat ttcatttcca ttatattgat ctaaataatc
    14821 acctctaagc acacttatca aaactggtat tgattttggt attggcattc ctttaaaaat
    14881 aattacatcc aaatatccat catctatttc agccttatat gctagattta tatttcctgc
    14941 tgttttgcca ttaaaaatca acataagata catatctcca tcataataca tttcctcaga
    15001 agatactttt atcttaaatt tcctcatata caatgcttct tctattccct ttatataata
    15061 agaaattctt ccaaatgaat tttttaagtc tgtgtttatc ctttgtgata catccgtaaa
    15121 cataccagca cttgcaacat ttataaagta cttattattg actttcccta tgtctatttt
    15181 ctttggtttt gaatttatga tttcatttat agcttctttt atatcaaatg aaatttgaag
    15241 agcatttgaa aaatcatttg cagttcctgt aggcaaaatt ccaattggaa tttttatgtc
    15301 taattctttc attgcattta ctactaaatc tacagtacca tcaccaccag ctatcaatat
    15361 gtgttcataa gaactatcaa cttccttaaa tgcattcttt acaggttctt taatagttaa
    15421 tctatagggt atcaataaat aatttttttc ttgatataat tctatgatag tgtctaaatt
    15481 tgataatatc tttttttcac ctgaattagg attgtatata agttttactt ttttcattat
    15541 ttctccttac tcattttatt cttttagtat ccaaaatctt catttaaaaa aatcacatgt
    15601 attctttctg gtgttaattg tctttttata agtgtataac tacagcatat tcttcctgga
    15661 cttgaacagt ctatacatat accagtagtc ttacatccag tatttgtact taatctttta
    15721 caattggctg gagcagctat tgtttttgtt ctttttatag cttcatctac atctttaact
    15781 attttattta ctcctgctat aactattact ttatcaggtc catatatcat agcagcaact
    15841 ctattcccat tcccatctaa attgtaaagt tctccatcct ctgttatcgc attagtactt
    15901 gtaaaataag catctgcaga aaatgacttt ctatatattt ctttcatttc ttctggtttg
    15961 atatcttttg catatctatc aagaaaatta tatttttctc ttataaaatc aatcactcct
    16021 gtttcaaata aggtcataga acctccacat cctactagag aacctgcttt aactatttct
    16081 tcaatttttt taagaagctc ttctttgtta cttactaaat accctttcat attattgttt
    16141 tccaaagatt ttattgtttt ttctattctt ttttcattaa gccaatttaa attttgatcc
    16201 attttaactt cccccttatt tttaatatgc acttaattat ttataaactt tattttcttt
    16261 ataagtttat tttagtacat ctaaaaaaaa atacaatata aaacttaaat agttttacat
    16321 aattttttcc aaaataactt actcaatcaa aaaaggaaag tagatgtact attctacttt
    16381 ccctatattg tatgtagtat ttattgccta aaatctatat attaattata tgtttcatat
    16441 tatataatat cacagttaat taaaatgtaa tactatcttc tttttaaaca tataaattgt
    16501 attattaaat ttaatatatc caacttcaat aaatcttatt aatttgatga agaagatgct
    16561 atagctgcac ttgttgctgc cattacacat gcaatttgaa tagcaacaac aatatttaaa
    16621 aatatattat tagttataga gcctatatta ttctcatttc gtatcaaatc tgcataaatt
    16681 gaagctacaa tagcagaact aatcattact ctattacttt ttcctaaaga ccaatttcca
    16741 aagccttttt cttctttaag tttatttgaa acatttttta tctcttctat tatttcatct
    16801 tctctataat ctaataatga aattgctcct attattggat atccataata attcatttta
    16861 caatcatttt ctttaaatgc ttttttaagt tcaatagtct ttttacattt aagcatagtt
    16921 ctatcatcac taaataaaag aatttgggat aatgcttgta aatcatttcc tttataaaaa
    16981 ccattttcat ttagaaattc ataacatttt tctatgtatt ctaaatcttc atctaaattt
    17041 tttgaatgaa ttgcaataag tgctatatta caatagtcat cactagaagt tagaaatgga
    17101 tgttttttcc tcatgtaatc atatattatt ttcatttttg atatacatgt aagataatcc
    17161 attttctctc tattttcata aactattgat gctgtaagtg gtaaatatgt atcgccccaa
    17221 aacttttcac ttttaagttc tttgtatata tctaaaatca tcttaaaact actttctgga
    17281 tttgattcaa acgaaagtag tgttgccata taaaacatat tatatcctct aaaattagag
    17341 aataatccag tatttttttt aataagctct attcgttctt ccactaatct aggacttatt
    17401 ctcttgttct taagggtaaa tgcaagtgca caactatgtt gtatcaatcc catttgccaa
    17461 gaacctttaa cttcatttaa tgctttgtaa ttttctatta ataagtttac ttttccattt
    17521 ataaacgatt gttccatatt gccctcctag taatatatct cattgtacta atagttttat
    17581 atttattata tatatattaa atactacaat caatacatat tacttcaaag aacatcattc
    17641 ttcaacaata atgtagcctt ttttgtaatg tcttcccata ttattgactc tatcatagta
    17701 ctctgattca ctttcattac tccatttggg cacaaataca tctattgcat tagaattact
    17761 aaaatactta ctagaccccc tatccataac agtttttaat tttccatcta caataatctt
    17821 agttccaaaa cttaagtgat tgtttgctac aaaaccatct tctaaatcat ctcctgtagc
    17881 agttatcgct ccatatccat tttcttgatt aagacttgtg taataactaa cttcaaaagt
    17941 tataggtact aacttcttta ttttaatacc taactgattt tgtagtttct ccttttgtac
    18001 tttcaactta tactcatcac tatttttata atcttccata ccttgattat acttggaatt
    18061 aaagctttta cctgacttta ctatagtatc tatatttact atagattctt tacaatgatc
    18121 tgcatctatt tttgtttctc catttaccaa taatggagtt aaacatacac tacatacaac
    18181 acatgtaatc aatgcttctt taagcttcat aaattccccc cttattattt tgatatatta
    18241 gcatatttaa tattatatgt ctacatttag atttaaatac cacacccatt tgctttaaga
    18301 agttgtctta tatttaattc accttaaaca cttataaatc ctctatctta gaatcatata
    18361 gaataaagct tttatcttta aatatttttt attaatcttt taaaatctaa aactacttta
    18421 tctaattttc tcttttttag aatttaagaa ttaaaattct ataattttaa aacatattga
    18481 atttattttt ttgagatgat ataattttct taagaggtgg ttgatatgat aaaaaataca
    18541 aaacaaatta cagtagaagt taatgaaatt ttattacaag aaatgtctaa gataactaat
    18601 gacgaaaata atattttgac agatttgata aatgaatcaa ttgtaaatta tattcttgaa
    18661 aacaaaaaac ataatattga aaataaagat ttagaagaag tgattaaatt ttacaaaaaa
    18721 gaaaatactg aaaaacctaa aagtgcagca agagctatag ctgaagcaaa aactcatact
    18781 ctgtattaat caaataaaaa agttcctaaa aactaggaac ttttttatat taataattat
    18841 taatatatct caatatttat ctcaaatcta tcaatataag catgtttaat acaatctatt
    18901 gtatacttat cttaccctag aaataatcaa aacaaaaata aaattatgcc ctttatatct
    18961 aaaacaatta atttacatga ttaatataca aaaattctga cttttaaatt cgtatacaat
    19021 atcaaactaa aataatatta atgacaaacc caatataaat taaattcaaa caggtttgat
    19081 tttacatcaa acttattgta ttaatattaa ataacaagac aaaaatattt ataaaaatca
    19141 caaattttac ataaaacttt atatttgatt catttaacta attattgtaa aaactattta
    19201 ttttatgata attaactaca ccaaattatt catctttttt aatatcctta acccattttt
    19261 caacagagtt caattcttct tcatttaccc cctttttgaa caaggatttc ataaaactct
    19321 caatagaact tccatgcata ttatctaaaa aagtttttgt ttcaaaatgt aaatactctt
    19381 cttctccaat aagaactgta taatgtgtat gtctatcaat ttttcttgca cttaagaatt
    19441 gcttatttac taatcttgat aaaagtgtta gtgttgtagt ttgcttccaa ttgtttttcc
    19501 atagcttcaa tgacatcttt tgatgctact gtaaaatctg aactccaaat aaatttcatg
    19561 acttttaatt ctgctggtgg tatcttagta atagtcatat gattttacac tcctctcaaa
    19621 cttctacata attaaatact atattaatag acttttcgag tcaaaggttt tatttaaaat
    19681 atctcatcca aatttattaa tacaaaaaat ttatattttt attcaaaatt aaacacacaa
    19741 tctattaata taaagataaa tatctattct ataagtataa cagattatca aattaaaatt
    19801 ctaatatttg acataatata tacatttttt aaataaatat atacaatgta ttaaaatgta
    19861 tgcaactcta tttcaaaatt attttgtgat atatatatgt tataataaat gtataaaatt
    19921 ttgattggtg ggttatatat gaatgcattt attagaaaaa gaaataaaaa ctatgttgtt
    19981 tacctggaat ttgaagatga aaagacaggt aaaagaaaac aaaaaaatat gggtactttt
    20041 gataaaaaaa gggaagcaag taaaagacta aatgaggtaa aagaaagctt atataatgat
    20101 ggttttttag taccaagcga aattacagtg tcagaatttc tattagattt tctaaataaa
    20161 tatagtgaaa atatatcttt agctacatat aataattatg ttagtatttg taagaattac
    20221 attaatccat ctattggaaa atataaaata caagacttac atccggttca catacaaaac
    20281 tacatagata aactatctta taaactaaat cctcaatcaa ttaagattca tataaatata
    20341 ttgaaacttg caataaaaag agcttataga ctcaaattaa taaaagaaaa tgttatggat
    20401 agtatagagg ctccaagata taaaaaattt aaaaatgaga tttatgatag agaacaaatg
    20461 ataaaattat tagatttagc aaaaaataca gaaatggaat tacctattaa tttggctatt
    20521 ggattaggtc ttagaatttc agaagtttta ggtctaactt gggataatat tgattttgaa
    20581 gaaaatacaa taacagtaaa taagataact tcccgaatta atggttctgt tattctcaaa
    20641 gagccaaaga cagaaagctc tgttagaaaa atatcttctc ccaaagaatt aatgtcttta
    20701 ttaaaagaat ataaaataaa acagaataaa aatttattaa aatcttccat tagaaataat
    20761 aataatttgt tatttttcaa taagaaatgt gaacctattg ctgaagatgt tatgagtaaa
    20821 aaatttaaaa gatttttaga aaagaatgaa ttacctcata ttagattcca tgatttaaga
    20881 cactcacatg ttactttact tataaattct aaagtaccta taaaggttat atccgagaga
    20941 gtaggacact caaatataag tactactcta agcgtttatt ctcatgtact taaagaaatg
    21001 gataaagagg cttctgacaa aatttctgaa agtttattta atgctaatta atattaattt
    21061 atcttagctt taaattagct tagcttattg agatagattc attaatatta aatgtatcta
    21121 tctcaaatta ataactactt aaataatctg ttttatttta atttatcgcc tcagttatta
    21181 tactttttta cgaaaaatta tactttacaa taaaaaagat attcccttat agaaaatatc
    21241 tttttaaata ctatattatt atatacttgc taacattgga atatctaaca tcttcttcat
    21301 tacatcatct actttttttg ctttatattc attgtatcca attaaatatc ctttttcata
    21361 tgaacttttt aaaatctctt tttcatataa attatcagat ttggcttctg tgacacttaa
    21421 attataaagc cctttacacc catcttcata acctttatta tacccttttt ctgcaaaata
    21481 gtttttatga tttttttcgt tatgtactga agatattgtt actccagaat tttcttttgt
    21541 actagcataa ggacaaaaac ctttattgtg ttgatgtgct gaatgtcctc cacaataata
    21601 acgtgttaac tctgatttat ttttattatg atgacctcct gatgaattat gccctcctga
    21661 gtgagcatat gaaaaattcc ctacactaat catagctaaa ctaattacta cagctactaa
    21721 ccttttctta accataatct attcccccca aaatgttata tatttttatt atatcatcta
    21781 ctatattata tttaaattct taatatacaa aatattactc tattctgcta ataaacatgt
    21841 ttaaacaata taaaaaacct cctaatattt gattaaaaat ttacacactc atgcatagca
    21901 tgtctcaaat attaaaaggt tttatactaa taattattta tcttttccat acattttagc
    21961 taattggtct tgtatctctt tactttctaa atactcatca aagtccattt ttctatccat
    22021 tattccattt ggagttatct ctataattct atttgctata gtagatataa attcatggtc
    22081 atgagaagta aataaaagca ctcctgggaa cttttcaagt cctttattta cagaagttat
    22141 actttctagg tctaagtggt tagtagggtc atctaataca agtacatttg catttgaaag
    22201 cattagctta ctaagcatac atctaacctt ttctcctcca gatataactt gagcttcttt
    22261 taatgcttct tcacctgaga ataacattct acctaaaaat cctcttataa aactttcact
    22321 tttttcttca gagaactgtc taagccagtc aaccaaagaa tattctactc cgtcaaaaaa
    22381 cttattatga ttttttggaa gataatcttg agaagtagtt actccccatt tatactctcc
    22441 actgtctggt tcaagttctc ccataactat gtttaaaagt gcagtagtag ctatttcatc
    22501 tcccataaat actactttat catctctatc caatctaaat gacacattat caagaacctt
    22561 aaccccatct atagttttag ttaaattgtg tacttctaaa acttcattcc caatttctct
    22621 tgcaggtgta aatcctacat atggatatct tcttcttgat ggttgtatat cttcaacttc
    22681 taatttctct aactgtttct ttcttgatgt tgcttgttta gcctttgaag cattagaact
    22741 aaatctagct ataaattcct ttaattgagc tatcttttct tcagtctttt tattttggtc
    22801 cttagccaat tgtaaagcca attgacttga ctcataccag aaatcatagt ttccaacgta
    22861 catttgtatt ttaccaaaat ctacgtcaac tatattagta catatttgat ttaggaaatg
    22921 tctatcatgt gatactatta taactataga ttcttctaaa tccattataa aattatttaa
    22981 ccagtttatt gatttaaaat ctaagtggtt tgtaggttcg tccattaata gtatttcagg
    23041 cttaccaaaa agtgattgtg ctaacaatac cttaaccttt tccccaccaa ctagttcctt
    23101 catttgtttg taatgcatat ctttcgttat gccaagaccc ataagtattt tctcagcatt
    23161 agtttctgca tcccatccgt caagctctgc aaactcacct tcaagttcgg cagcttttat
    23221 cccatcttct tcattaaagt cttccttcat atacaatgca tctttttctt tcattatgtt
    23281 ccaaagtctc tcatgacctc ttataacaac atttaaaaca gtttcttctt catattcaaa
    23341 gtggtcctgt tttaaaactg acattctttc tttatcagtt atagatatac tacctgtatt
    23401 aggctctatt tctcctgata atatttttaa aaaagtagat tttcccgcac cattagctcc
    23461 tattattcca tagcaattac ctttagtgaa ttttaagtta acatctttaa atagttcctt
    23521 atcaccaaat ctaagtccaa cacctgtaac ttgtaacatt aatatatttt cctttctttt
    23581 tgctcataat ttattttatc ataaaacttt gataacattt ttattatata ttatcacgta
    23641 aatagtatat tttttatact aaatttgtga aatatttatt aaaataatac taaaaattgt
    23701 aaatttataa aaattaacaa tctcttatat tatacttata aagaaatcaa attgcaactt
    23761 tattcattct tttacacatt gaaaataagt tattataatt tctaaataaa tatgcttttt
    23821 ttaaaacatc attctagctg ttttgtttca tatttaaaaa gagtacttaa tttgtaaata
    23881 ctctttttta ataactttat attttagcaa aattacatgc aggataagta catacatcac
    23941 agttcataca aaggccacca tgaccatatc tagctatatc atacttatca agcttttcat
    24001 caattaaaac cctagataaa actatatcaa atactgtagt tttgtgatac attgcgcatc
    24061 ctggtatacc cataattgga acttctccgt aataagcaag taaaaacata gctcctggta
    24121 atattggtga accatatgtc actaaatcag ctccagtttc ttttatagct gttggcgtaa
    24181 catcatctgg gtctacactc atcccaccag tacaacagat aagttctgct ccttgactta
    24241 taaattcttt tattgcactc tttataattt ctttatcatc tgggcatata gtctgtccta
    24301 taacttcaca accaaagcct tttacttttt cttctattac tggtccaaat ttatcaacaa
    24361 ttctgctata aaacacttca tttcctgtag taacaattcc tactttctta ggtttaaaag
    24421 gtactacatt tactattttt ctattaccaa ctactttttt tgcatcttct aattttttct
    24481 catctataac taaaggtatc actcttgttc cagctacttt taaaccttta tttactataa
    24541 aattattatg aagagtagcc atcattattt ctccaacaca attcaaatca aaaagtgcat
    24601 caacatctat ctttaataga ccatcacatg ctgctataaa atctattttc ccttctttta
    24661 tttcactaaa atctaaattt tctccagcag ttagttcttt taaaaacaat gcgccttcat
    24721 tttcatgaac cattccttct gacttttccc atacatacaa attatcttta ccaagagata
    24781 ataacactgg aatatcttct tcttttacta tgtgaccctt tttaaatttt cttcctttaa
    24841 attctccagg tattatttga gttatgtcgt gacataaaac ttgtccaaca gcatctatag
    24901 tttttattag cttcataatt tacccccaat tctctcatag tccatttttg tatcgatatc
    24961 aaataacatt tctttaggaa cttctacata ctttattttt gatgaatttt ttaaaatggt
    25021 tttacctttt tcatcttctt taagtgccaa caattcttct ttcttgctat atgggaatat
    25081 gactggattt ccacacatat ctttgtatct tggaattact ataaaatctc tatctaattt
    25141 aaaagtattt ataattttat ctatatataa gttatcaata aatggctggt ctcctacaaa
    25201 gaacatataa ccatcacatt ttgagctatt taaaactcct aattttatag attcactttg
    25261 acctatattt gcatttttat tatctatata ttcaaaacca tatttattac acaataacaa
    25321 aacctcttca tattgactta ctactacaac ttgatgaaaa tcaatcttgc taacttctct
    25381 aaatacatgt tctattatag aacagccttt ataatttaat aaaagtttat ttgctcccat
    25441 tcttctggca aagcctgatg ccattatcac tgcatttatc atatatatca tccttggtat
    25501 ttataatata ttgatagttc tatgattttt ataatatctc tattgatatt atctatatat
    25561 ataatatcat ataaactatt ttaatacttc aatatcttac acaaaatttt tgttttacac
    25621 ttccataaaa tatctctatt tcactttcat attctttaat attttctatt aattttatag
    25681 ctaaattttt atatttttca ttttcaactt tattaataaa taatactctt tttccagaat
    25741 aatttttaaa taatccattt ggatttaata ctatattttt taagttttca atacttactg
    25801 tagaactact attaatacta cttgtatcta aatttgctat ttttttaaat atttctactc
    25861 tatgtatatt ctcttcatta atattcattc caaatgatgt tatatctaat atccctatgg
    25921 tttttgtagt tctatgatat actactggtt ctttagcatt ccaaccttta agtttttttc
    25981 tctttgagcc atctccctct attaaaacta aatcaaattg gtctacaatt tcatccaaaa
    26041 tagaggaatc aatacttact aatttatttt cattatttat ataactgcca cagactgtta
    26101 ttccatgaca aatagatgga ataacagttc catctattgt aataattata ttgtcataat
    26161 cgtttggtac atatatttta gttgttgttg taagaagaac tttcaattta tttctataaa
    26221 aatttgcaaa atagtttata aacgaagttt ttcctcctgc tccaactaca gttattattt
    26281 cattcttttc tattatattt gatagttcca cactttcacc tcttataacc agttttctaa
    26341 tctcttaatt attatagtta ggccttttta gtaaaagtga tttttgaaat tccataaact
    26401 cgaaagtaaa tagattctgt tgtaaacaac aaggcggatc caattcgccg ctaagctgta
    26461 agcttacgct atcagtttat cttttaaata taattaagat attcttactc tctgtggttg
    26521 ctttaatatt tgaggattat tctgtaaatt agataaatta actacttgtg atttttttag
    26581 tatattaaaa ctcgcattta catctgcatt tataatgatt ccaacactgg atttgtactg
    26641 tccacgtgtt attctttccc ctttaaagtc atatttttta acattgtcca cattgatatc
    26701 aggtagaaaa tcatcagcaa aaaaatctga tttactagta tagctttctt cttgcctaat
    26761 aaaattgata ttttttattt tacacagata ttctaatttt ccttttatct ctccaaatgg
    26821 gattcttata aaatttctat atatttttct ctccatatta tcactttttt ctaacttagc
    26881 attatatcct acaattaaat ttccaatatt attttttaca caataatcaa ttatataaaa
    26941 acaggtttta tttacatagt ctttaacttg attatttctc ttattccaaa ctttaaattg
    27001 ttttcttgtt attgcagtta tattcttttt taattttaag gcttctattt tatcattctg
    27061 tttgtttgcc cactgattca cagattttag cctttttcca tctatgataa aactatcacc
    27121 taaattggta acacatgtac ataaattttc taaacccaag tctatagcta gtgcattttt
    27181 ttgatttgaa acttcctctg attttggtat ttcataacaa tactgaattt caaagaacct
    27241 agctttatgt ttaggtatta ttcttatttc tttaattttt ttctctagta tattttgtgg
    27301 aacttttata cttactttcc catatagttt tttaaatgct ggagacatag gtacatttaa
    27361 aatcccatct tctttgattc ttatttgacc tattattatg ctaaaaaatc cttctttatc
    27421 taaatattta ggtgatttta tccctctaaa gtcatatttt ccttctttgg ctaatttaat
    27481 taatccaaaa aatgacctaa acgaactgtc tacttctttt aatatttgtt gcgctatatt
    27541 actattgaga agcttatagt tctcattttc tttgcataca tgataattag cttcatagtt
    27601 aagatgttct ccttgattga aataatgctg tcttacatta tatgtaccaa cattatataa
    27661 gttcttagct aagaagcaca tctctcgtag agcttgatat tcttttttag ttaagttttt
    27721 taattgttgt ctctgagttc catagtgtat attttttatt ctgtttgaca tgaactcacc
    27781 tcctttagaa tatactctac tagacattat atacggtatt tttacaaaac accatatata
    27841 atgtccattt aattacttta ttttacaaaa taatttaaat ttacttgctt ttatgcatct
    27901 tattatttat tataattgtt tattattatt tttcataccc atataaactt tttcaaaagt
    27961 cataggaagc tctcttaaac gaactcctgt agcattaaat attgcatttg ctatagctgg
    28021 tgctggtgta tgtataacta tttctcctaa tgatttagca ccataaggac ctcctgggtc
    28081 gaaattctca gcaaaatcta ccaatatatt tccaacttct ttttttgtag gaactttata
    28141 ctgtaggaaa ctatctgtta ataatctacc atctttatca aatatagggt cttcatacat
    28201 tgcaaaccct atacccatca tcacaccacc ttctacttgt attctagcta aagttggatt
    28261 tataactgtt ccacaatcag gtacacatgc aaaatttatg actttatatt cacctgtatt
    28321 tttatctaat tctatctctg caaatcctgc tataaatggt tttatttttt tcaacatgcc
    28381 aaaagattct gttgcttcca aaactactgg tacatcatca ctagcaaatc ctattcctcc
    28441 aacagattct ctacccaatt cctctaatag aacaaacttg ctattatcgt ttttaacaaa
    28501 aaccctgtct tttcccaact ctaaatcttc ttttttaaat cctagctttg actctgcaac
    28561 tgaaagtaat atatctttta atttatttgc tgtctttatt gttgcatttc ctgtaaccgt
    28621 tgtcgtacaa gaagcaaatg ctcctgtatc atagggacat aagtctgaat cacctgtata
    28681 aatagaaatt ctatctacag tagtatttaa agcttccgca gcaatttgag cttgaattgt
    28741 atcagcccct tgacctaagt cagcaagacc agataatatt ttatatgtgc catcttcatc
    28801 cattcttata gtgactgttg ccatatctac acgcggtata ccagaaccat gatttgctac
    28861 tgccatacct actgctctta ctttgttgtt tcctatatct ttacatggat atttatcatc
    28921 ccaattaatt aatttctttc ccttttctat acattgtctc agctcacaac ttaatatttc
    28981 gtcttcagct gcttttccat tggtatacct atctattata tttttaattc taaattcaag
    29041 tgggtccatt ccaatcttat gtgccaattc atcaatagca ctatctattg caaatattcc
    29101 ctgtgtagca ccataccctc taagtgctcc tgctggtaac ctattagtat atactgttct
    29161 agcattaaat ctaacagcat caatatcatt atatattggt aaggtattgt gtccagattc
    29221 ggaagaaaca gagacaccat tcccaccata agcacctgta ttgtttaatg actttagctc
    29281 tattgctttt aaatttcctt ctttatctgc accaacttta acatcaaaaa acatttcatg
    29341 tctactatta gaacctacaa aagtttcact tcttgtaaat acaaattttg ctggtctacc
    29401 agttttcata gtaacaaatg cagtaaatat atctgttgct gctatattct ttcctccaaa
    29461 tccaccacct attctaggtt taattactct tatttttgaa gacggtatac ccaatacttt
    29521 tctaagtatt ctctttacat tgtgtggtga ttgtaatgat gaaactacaa caattctatc
    29581 atttatatct ttatatgaat atgacctatg agtttccatc atgcaatgcg attgactttg
    29641 ggttttgtat gaagattcaa ccacaaaatc actttcttta agcttagctt caacatctcc
    29701 aaattcaaaa aattcttttg atactatatt attttttgca tccaatccaa aagggtatgg
    29761 ctctactatg tctttttctg gatgtataac aacttcattt ccttctgctt ctcttgcatc
    29821 aaacacaggc tttaaaacct cataatctac ctttatcatt tttaaggctt taagtgctgt
    29881 tttctcatct tcagcagcca ctaaagctac ttcatctcca ataaatctaa ctgtatcttc
    29941 aagtaaaact ctatcataag gtgatgcttc tggttctgtt tgacctggaa cacaatatct
    30001 gacctgtggt acatctttat acgtataaat acccacaacc cctggaattt tttcggcttt
    30061 tgatgtatct atattcttta tcttagcatg agcatgtgga cttctaagta gttttaatgt
    30121 caaaacatct ttatgcataa tgaggtcttc agtatataga ggttttcctg tgacaattgc
    30181 tgtactatct atctttctta tccccttatt aatcattata cattccctcc tcaatagcat
    30241 tatacatcct tttaactaat gcacttgcca tatcctttct gtactcttta ctagctctca
    30301 tattacttcc ataagtaagt tccttactag caacaataga tgccttatct atatcttttt
    30361 ctttatttaa tatattactc gcttcaagtg ctaatctagc tttttgaggt cttgccccaa
    30421 ttgctatttt gtaagtatca ttttctttta gcattgctga atttaataca gaaaaatctc
    30481 ctgtgcattt tcttattgag tcaaaaacag ctattgcatc tttttttggt agtattactt
    30541 cgaccaatat atccctactt aattcactat ccaaaaactc acttaactct agtattcctt
    30601 tattgtataa tctcaccttc gctccaacaa ccaaaagtgc tggtattaag tcagaaaagc
    30661 catactttga aaatacactt gcaccaattc tagccccttg tctaaattga acaccaacta
    30721 tattagaaac agcgcttgaa agtattccac tacagtaatt ttttatagtt ttatcaattt
    30781 ctaaacttct aagtgaagta tctgcaccta tcaaaatatt ttttttatcc tcttttatat
    30841 aatttagatt tatatctttt aaatctatcg ctgttcctat atttttatta cttaatttta
    30901 taaatccaca tccacctaaa ataacattat tttttttaga aattaaaatt ttatatgctt
    30961 cttctaaact ctgtggaact gaatattcct ttatagtaac catcttatcc ccccatcatt
    31021 aacttattaa aacacaaaag tttttaataa atcttttatt tatatttata attgtagtat
    31081 atttaattca catatattaa acctttacat tataaacttt tatttttatc ctcaacctta
    31141 tcacttttat ttccaggaaa ttttaccata tataaagctt gaattattat ggctaccatt
    31201 gctcctgaaa ctacacttga atctgcaagt aatgtctcta taaattttgg aaatttttca
    31261 agaacttgag gagctaccat gaatccaata ccagaagcca tagaaagacc taatatcatg
    31321 ctattttctt gattaaatcc atccatacta acaagtctta aaccagatgt tgtaagagtt
    31381 gaaaatataa cgagtgttgc tcctccaacc acacagggag gaattgttct tattaaatta
    31441 gctaataaag gcgatattcc tgccaaaaat aatccaattc ctccaatagc tagtacaaat
    31501 ttacttacaa cctttgtatt ggaaacgatt gcagaatttt gtccaaacat ccccattgga
    31561 gttgcagaaa ataatgcacc tattgtagag agtactccat ttcctaaaac agcagaagaa
    31621 agttcttcat ctgttacttg tctattaagc cctcctaccg cagaaagtgt acaagcaccc
    31681 attatatcag ctatctcaac taaatatatt attgaaaaca ttacaacaac ttcaagtctt
    31741 atatctagcc caaaagcaag tggttttgga agtgcaacca aagtaaactc ctgaattgaa
    31801 gaaaaattta ctatacccaa aattaatgat aaaatgtatc caaaaattat gctaactaat
    31861 attgatgcat ctttaaataa tccttttcca tacttattta atcctaatat cataagagat
    31921 acagatattc caactataaa attaattgga ttcccaaaag tctcattgcc cataccccca
    31981 gctaagtttt ttatagctat tggaaaaagt ccaagaccca tacatgcaac tattgttcct
    32041 gatacagctg gagtaaatat aaatcgtatt tttttaagac caaaaccaat tataattatt
    32101 actataccag ctattatttg agagccaaat aatactggta gtccatactt acttgcaaca
    32161 gataccccag ctcctataaa catagctgta gctcccatta taactggtat tcctcctcct
    32221 aatttaaaac ctttaaacaa aggtattgga tataattgta ataaagttga taatcctgca
    32281 aaaactaatg cggcttgaat caataatgtt gacatcttat gattaagtcc agctgcattt
    32341 gcaatcaata tcgctggtaa acaactacct attaccattg ccattaagtg ttgtaaccct
    32401 aaaggtattg cttcctttag tggtggtatt ccgtctaatt caaattttga tgtacttttt
    32461 gctttcataa taaaaactcc cgttacataa aacttattga attatataaa tacttaaaaa
    32521 tctaatatat taaattaatg atgttcataa atatcaacta tactccaaca tatatttaag
    32581 tttttagtct taaaaaacag atgcaataaa tttaattatt aacaaataca cgtattcttt
    32641 aattttgtat acattatata ccatgcttta caaatataag agtattatag ctatgaattt
    32701 ttaatttttt atagtaaatt taattcaatt taaatctttc aatcttaatc attataagtt
    32761 ataagttttc ataagtattt acatgtttca agttttaaac atttacctat aaacgctact
    32821 ttatagatgt cacttcaaat ccagtgacct catactttca tatgagcgta gactatttct
    32881 tcatcttcag cattacctgc taagagcaac ccgtttccac tatcaatcgc ttatagtgta
    32941 ctctctctcg agatagtcgt ttgaccttcc tatttctagg cttggcgacc aaatgtccat
    33001 ttttaagtac ttaggctctc accatatacc atcctcacta ttgtttctgg ttttcaccac
    33061 attcataaaa gtttctttct atcttttatt gtagttgcaa ggctttagga tttactggtt
    33121 ttaaagttgt gtcctacata gatttctcta tgtacggggc caaaagtaca atttatttaa
    33181 catactttgc tttaccccct gtaaataata ttatttactc tttcactgtt tttgttatta
    33241 aattaattaa atatcaatta atctaagcat aaaataatta tttaatttaa actcaaaata
    33301 tttatgaata ttttataata taattctcat aagacagaaa aacttaataa gctatgtatc
    33361 tcagttgtac caatgtactc tcctttacta tatttgtatc tgcaacataa aatatacaag
    33421 tttctatcta ttt
//
LOCUS       DAEHWO010000043        31972 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEHWO010000043 DAEHWO010000000
VERSION     DAEHWO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31972
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.043"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            41..1348
                     /locus_tag="KNP54_002317"
     CDS             41..1348
                     /locus_tag="KNP54_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893214.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1434..1696
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1822..2625
                     /locus_tag="KNP54_002318"
     CDS             1822..2625
                     /locus_tag="KNP54_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0893215.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            2663..3274
                     /locus_tag="KNP54_002319"
     CDS             2663..3274
                     /locus_tag="KNP54_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBF0893216.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3306..3977
                     /locus_tag="KNP54_002320"
     CDS             3306..3977
                     /locus_tag="KNP54_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBF0893217.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4276..4638
                     /locus_tag="KNP54_002321"
     CDS             4276..4638
                     /locus_tag="KNP54_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBF0893218.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5074..5775
                     /locus_tag="KNP54_002322"
     CDS             5074..5775
                     /locus_tag="KNP54_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBF0893219.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDELCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            6046..6864
                     /gene="larE"
                     /locus_tag="KNP54_002323"
     CDS             6046..6864
                     /gene="larE"
                     /locus_tag="KNP54_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBF0893220.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            6919..8067
                     /locus_tag="KNP54_002324"
     CDS             6919..8067
                     /locus_tag="KNP54_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBF0893221.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            8203..9591
                     /locus_tag="KNP54_002325"
     CDS             8203..9591
                     /locus_tag="KNP54_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893222.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGDDSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            9620..10318
                     /locus_tag="KNP54_002326"
     CDS             9620..10318
                     /locus_tag="KNP54_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893223.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            10321..11754
                     /locus_tag="KNP54_002327"
     CDS             10321..11754
                     /locus_tag="KNP54_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0893224.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            11776..12513
                     /gene="truA"
                     /locus_tag="KNP54_002328"
     CDS             11776..12513
                     /gene="truA"
                     /locus_tag="KNP54_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBF0893225.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHSPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    12624..12831
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13084..14283
                     /locus_tag="KNP54_002329"
     CDS             13084..14283
                     /locus_tag="KNP54_002329"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBF0893226.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            14530..15576
                     /locus_tag="KNP54_002330"
     CDS             14530..15576
                     /locus_tag="KNP54_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBF0893227.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTGQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            15684..16847
                     /locus_tag="KNP54_002331"
     CDS             15684..16847
                     /locus_tag="KNP54_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0893228.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     NRNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(16936..17316)
                     /locus_tag="KNP54_002332"
     CDS             complement(16936..17316)
                     /locus_tag="KNP54_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBF0893229.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(17319..17978)
                     /locus_tag="KNP54_002333"
     CDS             complement(17319..17978)
                     /locus_tag="KNP54_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBF0893230.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(18084..19058)
                     /locus_tag="KNP54_002334"
     CDS             complement(18084..19058)
                     /locus_tag="KNP54_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBF0893231.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(19098..19445)
                     /locus_tag="KNP54_002335"
     CDS             complement(19098..19445)
                     /locus_tag="KNP54_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893232.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(19663..20619)
                     /locus_tag="KNP54_002336"
     CDS             complement(19663..20619)
                     /locus_tag="KNP54_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBF0893233.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            21064..21432
                     /locus_tag="KNP54_002337"
     CDS             21064..21432
                     /locus_tag="KNP54_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBF0893234.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            21857..22102
                     /locus_tag="KNP54_002338"
     CDS             21857..22102
                     /locus_tag="KNP54_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893235.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
     gene            22201..22464
                     /locus_tag="KNP54_002339"
     CDS             22201..22464
                     /locus_tag="KNP54_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBF0893236.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(22749..23696)
                     /locus_tag="KNP54_002340"
     CDS             complement(22749..23696)
                     /locus_tag="KNP54_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBF0893237.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLANTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(23699..25330)
                     /locus_tag="KNP54_002341"
     CDS             complement(23699..25330)
                     /locus_tag="KNP54_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBF0893238.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            25460..26377
                     /locus_tag="KNP54_002342"
     CDS             25460..26377
                     /locus_tag="KNP54_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0893239.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(26434..27015)
                     /locus_tag="KNP54_002343"
     CDS             complement(26434..27015)
                     /locus_tag="KNP54_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBF0893240.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(27055..27621)
                     /locus_tag="KNP54_002344"
     CDS             complement(27055..27621)
                     /locus_tag="KNP54_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBF0893241.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQINNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            complement(28077..28937)
                     /locus_tag="KNP54_002345"
     CDS             complement(28077..28937)
                     /locus_tag="KNP54_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBF0893242.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            29086..29976
                     /locus_tag="KNP54_002346"
     CDS             29086..29976
                     /locus_tag="KNP54_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0893243.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            30194..31948
                     /locus_tag="KNP54_002347"
     CDS             30194..31948
                     /locus_tag="KNP54_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBF0893244.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLIMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTESLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT        12391 a         3632 c         5064 g        10885 t
ORIGIN      
        1 atatattgag ttttacataa aagcaaaggt gggaataaaa atgaaagaaa ttgctgatgc
       61 tataacatca gagtatttaa gctatggtat caatgaagat attagtatct atgaaggtag
      121 attttgcata tatttagata aaaaatatag atgtaatggg aaaatttatt ataaaatgac
      181 acctccaata tctataagtt ttaaagcaga cataggttgt gttgaagaga tagacaatga
      241 agatgacaat ttagctttag attatgataa tgctattctt gaagttcatg gatataaaat
      301 tatttctata acaataaata ctttaagtga atttagtgta gaaggttata tcaatgatga
      361 ctgtataaaa tctaagaact cctatgttga atatgtagat tttaatataa taaacttaga
      421 taaaatacct ggaaaactca ttaaatacaa tgataaggta tacgcaggta gaattgaatt
      481 tgatataaat gattatgttg taactataga caagcgatat gattatagaa aagaattaaa
      541 atcagaatta aagtctaaat ctggagcaat aataactcat ataggcagga ttagaagaaa
      601 agatggtaga atttttagaa caaataatac aataaatctt ttagatagga tatcaacagc
      661 tttgagtttt atgtgtggaa gatatgtagg gttttgtttg gccaaagggt atagaagtgg
      721 taatgaagtt tatagaatat ggaatgaaaa tcaaatatct ccttttagat atgtaccaac
      781 atggtcagat acactttcaa attatcataa tatggaaaaa tatataagcc ttatgtgtaa
      841 aaagctagaa gatttttatt atggttctgc tataaagagt gttgttgatt ggtacataga
      901 atctcttgga agtgctacca tggaaaacaa tataatatct gtacaaattg cacttgaaac
      961 tttgtcatat gtaattctag tggaacaaaa taagatactt acagatgaag catttgactg
     1021 taatttggca tctaaaaata taagactctt acttgataca tgtaagatac catatggtaa
     1081 acatgaatta aatatatttg ataatataat aaaaaataaa tttgatgatg gagtggattt
     1141 agttatttat ttaagaaata gcatagttca tccaagtaga aagactcata gagctgtgtt
     1201 agaggttgaa gatatttgga atataatttc aataggaacg agatatattg aacttgtttt
     1261 actctttatt ttaggttata gaggagaata ttcaaacaga ttagtagaaa gatgttatgg
     1321 tgaagtggaa gttgtacctt ggaactagat ttttatattt attttaaaat atatattgac
     1381 atatattgcc ttatgctata aaatcaatat cataataata attcagaata acattaaatg
     1441 ctaagaaaag aaatagtaaa agtagttaat cttaaacaga gagtttccga ttggtgagag
     1501 gagcaataga ttttactttg aacacatctt tgagcaggac tctgaaagag tagaaatact
     1561 ttattaggag atttccggaa tccttgcacc cgttatagtg ctagagtata ataattttat
     1621 tgtacttaaa gaggttagtg ccgtgaggca ttaatgaaca gaggtggaac cacgagagtt
     1681 aactcccgtc ctctagcaga agctagaggc gggagttttt taatataatt ttttaagcgc
     1741 gcagagaatt atattgcaat agatacactt tttaaaaaat aatcaaaata ttttaaaaat
     1801 taaaagacga gggagaatat tatgaaaaat atattaaaaa aagtaggaat atttacaatt
     1861 atgttaggtt tattaggtgg agttgtaggt tgttcaaaac cagataatga aaaagataag
     1921 gatgcttcaa aggaatctaa aaaagaagta gttgtagggt ttgataatac gtttgtacca
     1981 atgggatttt tagatgaaaa gggagataca gtaggctttg acgtagactt agctaaagaa
     2041 acatttaaaa gacttggaat ggaagttaag tttcagccta tagattggtc aatgaaggaa
     2101 actgaattaa atgattcaaa aactgtagat gtattatgga atggatattc tataacagac
     2161 gaaagaaaga aaatagtatc atatacagaa ccatatttac aaaataaaca gataatagtt
     2221 actctaagtg actcaaaaat aaattcaaaa gctgatttaa aagataaaga agttggaaca
     2281 caacaaggtt caacagcact tgatgcagtg gaaaaggata aagattttat gaatagctta
     2341 aaaggtggag caccagttct ttatgatact tatgataaag cacttagaga tttagagata
     2401 ggtagaacta gtgcagttgt tggtgatgaa gttttaatta gatactatat gggacaaaag
     2461 ggtgaagaca aatacaaggt attaaaagac gattttggat tagaagatta tgttgtagca
     2521 acttctaaag aaaatccaga actttgtgag aaaataaatg aaacattaaa agaaatgaaa
     2581 aaagatggaa cttttgacaa gatttatgat aagtggttta aatagaagat aagttagctg
     2641 ttaagaaggg ggcactaaag gcatgttaca aggtttagag atagttatag caatgttttg
     2701 tataacattg atagtatcaa ttccattggg gattggagtt gcatttttaa gattatcaaa
     2761 gaataaatta gtaagtggta ttacacaatg ttatatattg ataatgagag gtacaccttt
     2821 acttttgcaa atgatagtca tattttacgg attacctctt ttaggaattg tatttgacag
     2881 atttacagct ggagtagtag ctttcttctt aaattatgca gcatattttg cagaaatatt
     2941 tagaggtgga atacagtcaa tcgatagagg acaatatgaa gcttcaaaag tactaggatt
     3001 tgataagttt actatgtata agagagtaat ctttccacaa gtttttaaaa gaatactagc
     3061 acctatttca aatgaagtaa tcacattagt aaaagataca tctttagtat atatattagg
     3121 attaaatgat attttaagaa tatctcaaat agcaatgaac agggaagcaa gtctgttacc
     3181 attatttgag gcaggagcga tatatcttat atttgtagct atacttacta agggatttga
     3241 attacttgaa aaaaaatatt cttattatag ataaagttac aatattatag gaggaggttt
     3301 tttatatgtt gaaaatcaaa aacttaaata aatcatttaa aaaaaataga gtacttaaag
     3361 atatttcttt tgagttagaa gaaggtcaga ttggagtttt acttggtaag tctggtgcag
     3421 gaaagaccac aatattaagg tgtataaatg gtcttgaaga atttgatagt ggagagatta
     3481 taatagataa tgaggtaata aaaaataaga gagatatggc aaaaatacga ggaaaaatag
     3541 gtatggtttt tcaaaatttc aacttatttc ctcatatgac agtccttgaa aatataattg
     3601 aatccccagt taatgttttt aaagttccta gaaaagaggc tgaagagagg gctagagaac
     3661 ttttaagatt agttgattta gaagataaat taaattctta tccatttgaa ttgtcaggag
     3721 gacagcaaca gagagttgct atagctaggt catgtgcatt gatgccaaaa gtcctttgtt
     3781 ttgatgaacc tacttctgca cttgatattg atactattca aagagtagtc aatataatga
     3841 acagacttaa agacaaaggt atgacaatat taataattac acatgatgtt gtcttctcaa
     3901 ataatgttgc agataaaatt ataagtataa aagatggtat agtagaaaat gttcaaataa
     3961 aagaaaaaat tgtttagagt tttataaata taaactaggg tagaatttta taatataaat
     4021 aaagggcaag taaaatcaaa tatactatgc ccttttgtta tctcaaaatt taatcttata
     4081 ttttatgttt aagttacatt ataatttata ataaaaataa aaggactatt taaatatata
     4141 atgtgaataa atgtttaata atttgaaata tgataatttt ttatgttgaa agcttataat
     4201 gattatgata taaattggtt atagtataca atttatgggt ataacaataa aaaattagaa
     4261 aggaattttt ataaaatgat taaattatat ggatatacaa aatgctctac tgttaaaaaa
     4321 gctaaaaatt ggcttaagga aaataattta gaatttgaag atatagatat ggttcaaaac
     4381 cctcctagta aagaggagtt aaaatcaatt tataagacta gtggatatga tataaagaaa
     4441 ttttttaata caagtggtat gaaatataga gaattgggtc ttaaagatat tgtaaaaact
     4501 gaatctgatg ataaactttt agaaatattg gtaagtgatg gtatgcttat taaaagacca
     4561 ttacttttgg atggtaaaaa tgtattattg ggctttaaag aagatgtatg gaaaagtact
     4621 ttgctaaaag aagattagga agagataggt gtgttgatta aaattattaa ttaatacacc
     4681 tataaattta tgtattaaat ctaattttta taaatattaa ttagcaaatt caaatcaaaa
     4741 aaattcatat caacaaacat attacttctt attacaaatt atatcatatg ttttatatta
     4801 aaatattata atattacaac gaattgttac aaaattactt attattaacc atgaacattt
     4861 gttttgtgct atcatattta tataagggaa ttgtcataaa aaatatcttg ttcatacagt
     4921 tttatataga aaaaagaaat gaatcttttc tttatataag tatattttgt aaattgcctc
     4981 tatatttata gtttaaataa tagtggtatt aaaaatctga caacaaaaat aaaactttca
     5041 aaaaattaaa tctaaaaaga ataggagata aatatgagta ttgaagattt atatgatttt
     5101 gaatgtgttc ctttgaacaa tgagattgat attgatgttt tatttgaaaa gatgatagaa
     5161 gatggaaaag aaaaagaata tacaccaatt atagtcattg atgaaaaagt agggctatta
     5221 agaaaaaata tagatatgat tactaaagag tatggttctc ttgaaaacta tagagagtat
     5281 tgtttaacaa aatataatga aattgatgta aatcaatttt ttgattttag gaagagtgag
     5341 atttcagaat tattaaagga gctaattgat ttagaagatg atttttatga ttataaacat
     5401 tttagaccaa ttatgaatat agatatattt catgaatata acaaagttta catagctaaa
     5461 attccaacaa ttaaaccata tgaagtattt gcatacatac ctattggcgg atttaatgat
     5521 tgtcctagag atgaagaaca tatagctatt gcaaaatatt ggtatgaaaa gcatggaatc
     5581 tttccaatcg caattggatg tgatacagtt caatattctg taaaaaattt aactaaagat
     5641 ggtaaaaaat ttgatgaatt atgtattgaa ttagtatttt attgtgagga tattattata
     5701 caagggtatg aaaccttaaa ggctcttaag gatgtattaa aacgctctac aatagtgctt
     5761 ttttggtggg attgatattc catcatttag atagtattaa attgttagtc accaagaatc
     5821 cacttgcttt agttatgggg agtgtgtcaa actaggtttt tatacacagt gtagcatagt
     5881 aatatgttta aattacaaag gttaaaaaaa tactttaata tttttaatat tataattaat
     5941 agatttaaag gtaattataa tttataaaat aaatacttta tatgttataa tcattaagaa
     6001 tgtaaaaaaa taatatatag ttttatagtt catatttttc cagatatgga ggtaaatttt
     6061 gtgaaggaaa aagaaaaatt agataaatta aaaaaaatgt tacttgaatt aggcagtgtt
     6121 gtagttgctt attctggtgg agtagatagt aattttttgc ttaaggtcgc aaaagataca
     6181 ttaggtgaaa atgttatagc tgtgactatt catgcaatga tgcattcaag tagggaaatt
     6241 gaagaggcta aacaatatac tcaaaatttt ggtgttaaac atatcatatt aaatatagaa
     6301 aactttgatt taaaagaatt taaagaaaat ggtgttgata gatgttatca ttgtaaaaaa
     6361 tatatattct ctaaaataaa agaggtagca aaagaacata atataaagta catagtagat
     6421 ggaacaaata tagatgattt aggagactat agacctgggc ttaaggcatt gagtgaatta
     6481 ggagtaatta gtccattaaa agatagtagt ttaaaaaaag aagaaattag gtcgctttca
     6541 aaaacattag gattaaatac ttttaataaa ccatcatttg catgtcttgc gagtaggata
     6601 ccttatggag ttgaaataac agatgaaaat ttaagaatag tagaaaagag tgaagaatat
     6661 ctatccaatt taggtttttc tcaatttaga gtgagaatgc atggagatat agctagaata
     6721 gaagttggac aggaagaact aggtaaattt tttgaaaata acaattttaa taaagttgat
     6781 actaaattaa aaatatttgg ctttaaatat gttacactag atatgtcagg atataaaatg
     6841 ggaagtatga atttaaatgt gtagattatt ttaaaaataa ataagtttta tagttaatat
     6901 aaggaaacag gaggttttat gaaaaattat acgttaatat cgccatgttt ttttggaatg
     6961 gaaaaaatgc tggctagaga gattactaat ttaggatatg aaataataaa aacagaagat
     7021 ggaagaataa catataaaac tgatgagttt ggaatagcaa agtcaaacat gtggttgaga
     7081 tgtgctgaaa gagtacatct taaaattgct gaatttgagg caaaaagctt tgatgaatta
     7141 tttgaaaata caaaaagaat aaactggtct agatatatac cttatggagc tcaatttcct
     7201 atatcaaaag cttcctctat aaaatcaaaa ttatacagta caccagatgt acaagccata
     7261 gtaaaaaagg ctatagtaga aagcttaaag aaaagttatt tggaggatgg tttgcttaaa
     7321 gaagataagg agaaataccc tatttttgta tttatacaca aagataaagt aaccatttct
     7381 atagatacaa caggagatgc tttgcataag agaggatata gagaaaaggc aaataaagct
     7441 ccaataagag agactttagc tgctgggctt atttatttaa ctccctggaa agcaggtaga
     7501 gttttagtag accctatgtg tggttctggt actatattga ttgaagctgc tatgattggt
     7561 ataaatatgg cacctggctt aaatagagag tttatatcag aaaagtggag aactcttgat
     7621 aagaaaatat ggtgggatgt aagaaaagat gcttttaata agatagataa tgaatctaaa
     7681 tttaagattt atggatatga tatagatgaa gaatctatag atatagctag agaaaatgct
     7741 gaaatagcag gtgtagatga atatatagag tttaatgtag gagatgcaac tcaatttaaa
     7801 agtgaagatg agtttggatt tataatcact aatcctcctt atggagaaag attagaagat
     7861 aaagacagtg ttaaacagtt gtataaggag cttggttatg catttagaaa attaaaaaat
     7921 tggtcgtatt atttgataac ttcttatgaa gactttgaat atgagtttgg gcaaaaagca
     7981 gataaaaaaa gaaaattgta taatggtatg ttaaaaacta actttttcca atatccgggt
     8041 cctaagcctc ctagaaataa taaataagtt ttacatgatt tatttgtaaa atataaaatt
     8101 ttattaaaat aagtaaaaca ttatgatgcc ttgaaacgtc taattattgt gaggagattt
     8161 ttgtgaacaa atttaaagat ttataggatt aggaggagtt aaatgaaagt gttaaagctt
     8221 attactgtag tagccctgat gatgttattt gttactggat gtaatataaa aactgaatct
     8281 ccagaacaat tagcgaagat acctgactat gatgatacaa aaaaagtatt gtatgatggt
     8341 attgaccagt tactaaaacc agattcatct atgatattgc cttctaatac aaaagaagta
     8401 ggaaaaataa ataaggtaga tttaaacagc gatggaattg atgaattagt agtatttgaa
     8461 caaaaagaag atttaagtaa taatgtgagt caggtagggt ttgtaacctt gagttacaat
     8521 ggagaaaaat acgtacttgg agaccatttt ttagaaaatg gcgaatcaat agaatatgct
     8581 aatttttatg atttggactc agatggatat aaggaagtta tcttattggt taaatccaaa
     8641 gacaaaacga atatgcatat atataaagta gtagataatg aaataacaaa aatatatgac
     8701 ttggatgcat catggcttca aaataaagaa gattttaatg atatgaaagt aaaaattgga
     8761 tatatagatg gagatgacaa gttagacata ttgatgcttc atttgaataa taagactaat
     8821 gaaatgtttg caagtgttgc aaattttgat gggaaaatga aaatcaaaga ttctgttaag
     8881 tttgaaaatg taaaaaactt aagtgaatta tatataacat taggtaatgt tgcttcatct
     8941 gttggaaatt cttctgcagc tataaaaggt attgtacttg atattcctat attgaaagat
     9001 aataactata ttacgcagat actttatatg aaagatggga aaattaacaa agcttttagt
     9061 gattatgata aaactattac taaatcttat tatatacctg tagatgatat tgacaaagat
     9121 aagattatag aaatacctat agttgcaggc agtacaggta ataataaaaa tacttatagt
     9181 tctaaatcat ctgcaactat aagttggtat agatggaatg gaaaagaagg tgatgactca
     9241 agtttaatat ttacaagtca gatatattat aattataaat ataattttaa attatttatt
     9301 ccaaataatt tatttgataa aatacttgtt gaacaggaat ttgttggaga aaaagcagta
     9361 tttaaatttt actattttga ctattcagac cgtaagaatt tatttaatat agtagtagag
     9421 agtaaaaata aacttgaaga tagaaaaaat acaggtactc aaaattctat tgtacttcaa
     9481 gagagcgatg aatatacttt cttactagtt gtaaacaatg caaatgaaat ggataagcta
     9541 gatatgacta tagacgcatt aaaagaatat ttctcattaa tatatggtta atattatact
     9601 caattggagg ttttatttta tgaaggaaaa gatacttata ctagaagatg aaattggtat
     9661 tagaagtttt gttagtataa acttaaaaag ggaaggctat gaaatagttg aggcaggtac
     9721 tggaagagaa gctatagaaa aaatgacaac agaaaaggat attacaatag ctcttttaga
     9781 tgtaatgctt ccagatataa gtggtataga agtatgtaaa tttataaggg agaattttga
     9841 ccaagtaggt ataataatgc ttactgctaa agctcaagaa gatgataaaa tagaaggatt
     9901 tatctcagga gcagatgatt acatcataaa accatttagt ataaaagagc ttttagtcag
     9961 agtttctgct cttcttagaa gagtagcaaa ggatgattca agtgttaagt cgagtgagat
    10021 agtttctcca ccatttatac ttgatataga caaaagaaaa ttatttaaaa atggaaagga
    10081 aattgagctt acaccaactg aattttcaat agtgaaatat ctaatatcaa atgctaagca
    10141 gtcgttaagt agagaccaga tattagacga agtatgggga actaactatt tatatgattt
    10201 taaaatagta gatgtaaata taagaaggat aagaaataaa atagaagatg acccatcaaa
    10261 accaaaatat atacaaacta tttggggtta tggatactgt tttagaaagg aagaataata
    10321 gtgttacatt ttgaaggtct gagaaaaaaa gtaataaaaa actattttat aataattatt
    10381 ataatggtta ctctgtttga aggattgttc atgttttaca tacaaaacta ctattatgat
    10441 tctgtcaaac agctacttga atctgaaata aaatatgctg atgaatataa tgctattaca
    10501 atggaaacta caagttttga gaaaaaagta aaaaatatat ttgataaaca acccttaact
    10561 aaaaattcag aatttggaat ttcaataata gataaagata aaaatattat attagaccaa
    10621 tatggtttta aaagtaaaga aaaagcaaac tatgaagatg ttaacaatgc attaaaagat
    10681 ataaaaacta aaaatttaac accttatact tatagaatac cagatacagg ggagcatgtt
    10741 atgagtatct ccttaccact taaggtaaat aatataatag aaggtgttgt tagatataca
    10801 gtatcattag atgctattga taatgcaata ttaaagcaag ctacatggct tatattagca
    10861 ggaatattta tacttattat agctatacta ataagtctta aatttgctga gactcttata
    10921 aaaccattac gagagctaaa gaaatttgca aatgaattgg ctgtaggaaa ttataatata
    10981 aaattagaaa agatgaagat tgtagatgat gaaattggtg atttagcaca gacatttgaa
    11041 cacatggcac atgagattga caaaagtgaa aaattaaaag aggaatttat atcatctgta
    11101 tctcatgaac taaggactcc tcttacatct ataaaggggt ggagtgaaac cttaggttat
    11161 gaaagtataa caagagaaga actagactta ggtttaggca ttatacaaga tgaaacagaa
    11221 agacttataa aactagttga agaattatta gacttttcaa ggctttcttc agacaggata
    11281 aaacttcatg ttgatatagt tgatgttgaa ggtttaattg taggtgttgt aaatcaactt
    11341 aaagttaaag cagctgaaaa agatatatca cttttatttg aatttgaaaa tgaatttata
    11401 gagaacattc aaggagataa aaatagatta agacaggttc tcataaattt aatacaaaat
    11461 tcatttaaat ttacgagtca aggtggttac ataaaagttg tagcttctca agatgaagag
    11521 ataacaacca tatcagtaga ggataatggt tcaggtatag aaaagcaaaa tttaaataaa
    11581 gtgttagata aatttttcca agaagattat aataaggctg gtagtggatt aggactagca
    11641 attagtaatg aaattgtaaa acttcatggt ggaagaatga aaatagaaag tgaaaagaat
    11701 gttggaacaa aaataacttt taatataaaa aataaatttg ctaaacaagc ataaattctt
    11761 agaaagagga ttaagatgag aaacataaaa atgatagtag catacgatgg ttcaagatat
    11821 aaaggatatc aaaaattagg tgacaataat atgactattc aagaaaaact tgaaaatgtt
    11881 ttaagtaaaa tgactaatga aacagtggag ataataggtt ctggaagaac tgatatggga
    11941 gctcatgcaa gaggacaagt ggtaaatttt agaactaatt gtatggattc tttggataaa
    12001 attcaaaaat atttatatga atatttacca gaagatatag ttgtaaaaac tgttgaagaa
    12061 gttgatgaaa gatttcattc aagatacaat gtaaaatcaa aaacttatat gtataaaatt
    12121 gacaataata agtatcatag tccttttata agaaaatatg ctactcatgt aagtaaaaaa
    12181 ttagatttag atagaatgag aaaagcaagt gagtatttag taggagaaca tgattttacc
    12241 agttttgctt cttctaaatc taagaaaaaa tcaaatgtaa gagaaattta ttctataaat
    12301 ataaaagaag atgataatgt tatagaaata tatgtagaag gaaatggatt tttgtataac
    12361 atggtaagga taatagtagg tgctttaata gatgttggtc taaaaagaag agctccacaa
    12421 gatattaagt atatgcttga atcaaaagat agatgtcaat catcagatac tgcaccagct
    12481 aaaggactat gtctttggaa agtaacatat taatcaatta tataaaactc tctttaaaat
    12541 aaaaataaaa taaattatat agttgacata aatggaaaaa taaactatta tatattttat
    12601 aagagagata taaaacttta tatttaaatc ctgtgagaaa gagagtaact tctatgtgtt
    12661 ttatagagag ctgaggatgg tggaagcttg gcaaataagt attagtgaaa agaactttgg
    12721 aggatactaa ttgaatttag tatgttagta ggtaatctcg ccttaagaga aagagtggat
    12781 aagtttatct tatcaattag agtggtaacg cggatatatt tcgtctcttg gtttttccaa
    12841 gaggcgtttt ttaatatatt taattattag tgtttatctg gtatgttgaa catttactaa
    12901 ttgattagct aagtttatca ataagagtgg taccgcggat atttcgcctc ttagtatttt
    12961 aaaatactaa ggggtttttt tagtattaaa atgattttat gtgagtctaa attctcagag
    13021 tcattcaata ttaagaattt ctataaaata aaaattataa tttaagattg ggaggaatta
    13081 aaaatgaagg aaaaagtagt attagcatat tcaggaggac ttgacacatc aatcataata
    13141 ccttggttaa aggaaaatta tgaagatata gatgttatag ctgtttgtgg aaatgtaggt
    13201 caggaagata aaatggaaga tgtatatgaa aaagctttac aaagtggagc atcaaaggca
    13261 tatgtggatg atataagtga agaatttgta actgaaacta tatttaaagc cgtaaaagca
    13321 gaggctaaat atgaaggaaa atacttatta ggaacttctt tagcaagacc tataatagct
    13381 aaaaaattag ttgaagttgc tcataaagaa ggtgcaaaat atatatgcca tggatgtaca
    13441 ggaaaaggta atgaccaagt tagatttgaa gctacaattg cagctcttga cccgactata
    13501 aaagttattg caccttggag aatttgggat ataaaatcaa gagaagatgc tatagactat
    13561 gctgaaaaac ataatataaa ggtaacagca actaaagcta aaatatattc agtagatgct
    13621 aacctttggc atgtttcaac agaaggtgga gatatagagc acctagaaaa tgaacataaa
    13681 aaagatgttt ataaacaatg tgtagaccca gaagatgcat gtgatgtagc tgaatatgta
    13741 gaagtttact ttgaaaaagg tgtacctaaa aaggtaaatg gtgaagaatt atctccagtt
    13801 gcactgattc ataagttaaa tgagttgggt tgtaaacatg gaattggtgt tatagatata
    13861 gttgagaata gacttgttgg tatgaaatca agaggtatat atgagactcc aggaggaaca
    13921 atcctttatg aagcacataa tattttagaa agtgctactt tagacaaaga tacattacat
    13981 ttcaaacaaa tggtatctta taaatacgga gaacttattt acaatggact atggtattgt
    14041 aaattaagag aatctataga tgcatttatg gaacaaactc aagataatgt tacaggaaca
    14101 gtaaaagtta aactttacaa aggaaatata aaacctgctg gaatatttac tgaaaatgct
    14161 ctttatgatg aaggaatatc ttcttttgga aatagtgaac tttatgacca caaagatgca
    14221 gaaggattta ttaatttatt cactttacca ttaaaaatca gagctatgaa agctggaaaa
    14281 taataaaata aattatttaa gagtgtataa aaactatttt taggttttta tatgctcttt
    14341 ttttatttga atttattaac ttatacagta aatagtataa aaaaatatat tatagttcca
    14401 aatggcttaa taatgtgaaa atataagacc taaaatataa attttataaa tacaatagtt
    14461 attgactctc tcattgtaag agggtttata ctgaatctaa tgaaaattta tagtgaggag
    14521 atagattata tgagaaaaat aattgaaatt aaacatcatt cacatgatta tgagtgtatg
    14581 tggaatggta tagaagattt atatataaat aaaaccggtg aatgccttcc aaacgatttt
    14641 ttctttttac tgtcaggttt tggttcattt tgttatatga aaacaaataa agctgatttg
    14701 aaaagaatgg tagctttggg agatggaagg acaaaacaga tgtataaatt tttagcacca
    14761 attgttggat ttgaatacaa acatcatgag tttaaaaagt atgagcaagc attaaagaaa
    14821 gcaaaatctg aaattgatga tggatatcca gttattttag gagctttaga tatgtattat
    14881 ctaccatatt ataagaagct atatcataaa gaacatattc cttttcatta tatattaatg
    14941 gtaggatatg atgatgaagg aatatatctg tatgattgtg gtagaacaga attattacat
    15001 ctttcttatg ataaattacg tgaaagcatg aattgcaatt cccctggatt aagcaaagaa
    15061 aatactattt gcacaataag aatgaatact tcaaagaata aatataacat tgctagagaa
    15121 gctattgcta taaagcgtga tatgttttta aatccaccta aaggattttt gggatataaa
    15181 ggttttgaaa agtttattaa agagttgcca cagtggaaca ctgaattgga taaagatgat
    15241 tatgataaga ttttgaccaa tatggttatg ttttttggaa cagtaccaac aattccaaat
    15301 gcaatcaaag gaattaaaga accagatact gttcaattta aaggtggatt tgataaaatg
    15361 agtagaatgc tcaacagtat tggggaggaa tacaaaaacg actcttttat acaagtagct
    15421 gatatttttg ataaaactgc tattataatt gagaaaatat ccaatattat aatagattac
    15481 ttaactcaaa catgtgatga tacaggacaa cttccgttat tgttctctga ggtcttagag
    15541 catatgaaaa caggatattt aatcttggat gtataaaaaa tatattgttg accctaacat
    15601 tacgtaatag tgtaatatga aaatatagct tgaatatatt agtaggtatt gatggctgta
    15661 aaattaaaat ttgaggtgtg gatatgagaa cagtgaaaca agtttctgat ttaactggaa
    15721 taagtgtgag ggcattacat tattatgatg aaataggtct tttaaaacca aataaaatta
    15781 cagatgcagg atatagactt tatgatgatg aatctattaa aactcttcaa caaattttat
    15841 tttttaagga gattgatatt cctttaagag aggttaagga aataatgtca agccaatatt
    15901 ttgataaggt tgaagctcta aaaaatcaaa aaaaattact tattttaaaa cgaaagagac
    15961 tggatgaatt gatagagctt ataaatcaaa ctctaagagg agaaggaaat attgatttta
    16021 aagagtttga tatgagcgag tattttgatg ttttagaaga atttaaaaga gagcatagga
    16081 ataaggtaat taaaatttat ggtagtgtag aaaaatacaa tgaatatata gaaagagtta
    16141 agtctaatga agagaaaatt gctaaaatgg ctataaaaca atatggaact attgagaagt
    16201 ttgctaaagc tataaaaaca aattttagca gtgatatatt gaatttagga gaaaaatttg
    16261 atagatataa aaatgattgt ttaaaagaaa aacatccaaa attaaaagaa ttatatagaa
    16321 agcttgtaga agatttaaat aggaatcctt cttcaacaga ccttcaagaa atagcaaaag
    16381 agataacaga tatatctaaa aaagattatg aaattttctc tatggatact ggtgatgaca
    16441 actggtatta tatggttcaa aattatctag taaatcctat gtggatagaa gaagtagata
    16501 aaaagtatgg aagtggagca ggtaagttta ttggacaagt actaaagact tatctaagag
    16561 atagaaaacc aaagataaat acattgtatg aaaaacttgt agaagatttg agtagagatt
    16621 gttcttcaag ggaagttcaa agcattgttg aagaaataga caatgaaatg aaaagaagta
    16681 atgaatttta taaaatagac aatggtgaaa gatactttga ttatatgtca gagctttatt
    16741 tacaagattc taactatata aaagtaactg ataagaatta tggtgatggt gcatctaagt
    16801 ttattggaga agcttttaag atttattttg ataataataa ttgttgaaaa tttggaagta
    16861 aaaaatatgc aagttttata aaagcacaaa aataaggatg tagattagct ccatctatat
    16921 ccttatttaa agttattaaa atatatagtt tacatcaaac ttaacacttt caataatatt
    16981 tcccaaatat gtttttatac tttcaacttc ttctaaagat tttaatttat tttcagtata
    17041 aattgctttg tccagaatat taaaccttaa tcctatttca tcaaagtact catgatttaa
    17101 aactttgtac caatggtttt tttctttatt ccaactcgta gatattgaat cagcttcttt
    17161 ttgagctttt tcccaatctt cattttctat agatttttct aaaacagata tattgtcttt
    17221 atatccttct gtaaaatcat atagtttatt gttaacataa aatccaaata atacaaataa
    17281 gatagtccat agtataacaa atgttgtaga tttcaatatt aatcaccctt tttattttga
    17341 ataaatattt tgtcattttc atctaaaaca caaataagaa catctttaaa agtttctatg
    17401 tgattagatt ttaaaatacc cattaaccag ttagtatctt tttgagctat gtctagattt
    17461 ttatttatta ttctaccatc cagtataagt gggataggta aatgattaaa agctcttgga
    17521 ggagtactat tgtagcttga tgctggtaca acacttagat taccatcagt ctccaaaata
    17581 gcatattgta catcttttag gttaaagtat ccttgaatcc taagttgttc taataattca
    17641 tctatactaa ttctttcttt tttaagctct ttatatacaa tttttccttt atctattaat
    17701 acagaaggtt tacctgataa aaatgaactt aattttctac tttttaatga taagaatgaa
    17761 attagagtct gcatgattac aagtccagat attgctgcaa caccatttat gattggtata
    17821 ttattatttt ccattgggac agatgcaact tctgcaatta atagtgttat aactaaatca
    17881 aaacagttca tttcagctat ttcacctttt cccatgactc taagtgcaat tagcactgtt
    17941 atgtataata taatacttct tattaatact actgtcatat ctatcaatta ctcctttaaa
    18001 aaatatttac acttagttag tatatcctat ataaaaaatt taattcaaag tataaaaaac
    18061 cttaaataat tggattcaac tatttaaggt ttttttgata attttaatat taaatttttt
    18121 atggattttc tgttactttt atttatttta ataacagatt caacaaaact ctttttatct
    18181 cctaatttta agataaaatc aggatattct tcaaattcat tgagttttat taatttgaaa
    18241 gaagaagata gatttttaaa gttaataatt ttagagttat tcactaatac acttcttttt
    18301 ttaaaataaa tttctttttt acttatattt agtatagtta atatttgttt aagatatatt
    18361 attatatctt ctggagttct atcaaatttg agttcaaaat tttcatcttc aaagtaggga
    18421 atataatata aaggtgtttt gagagcaggt aatttattat ataattcttc aagaatatcg
    18481 atatttttag gggagttaaa gaaaaagcat ttacatacat tcattaaatc cacagcatct
    18541 gaaagtgagt tatgtttaat atctccttct acagaaaaaa tttttttcat attcagtaaa
    18601 gatatttgct tagataagat tctattattg tatgtaatat gttgagatat aaaaggttga
    18661 atgtcaatca tcatattaaa taactctaag catttacctg tatatttata tactctaaat
    18721 gaagttagaa ggccagttat atcaaaatca ccccaattat atattgtaac atcatcaaat
    18781 ttacaaaacc atttataaaa atcatccata acatataaaa gattaggagc attattgata
    18841 tctagttggt tcaatttggt taaattttta catttatttg aaagtatttt attgtatttt
    18901 ggcttaacta aagagtaata attatctatt gtattaaatt cgttatcaac taaaactcca
    18961 ccaatagaaa ttaattccgc accattatat tcttttggtt tatttttatt atcatctagt
    19021 atattaaatt caaagtctat aaataacttg tatttcataa atctaaagca catcctcagg
    19081 taaattattt attgagccta agcatcataa gaatcaatag atataatgac tctaaacatc
    19141 aaaggttcat tacaactttt atttatttca taatttaatt caaataaatc ttttaagata
    19201 taatttataa gtattctttc ccaacccatt tttaaattaa ctttagagtc tattaatata
    19261 ttttctatct ttttaaatat ttctatattt gctggtatta tactgagctc aatattactt
    19321 ttaaacgggt tagactgtaa atctgttata agtatatttt ttaattcctc tgtaagttca
    19381 gaaattaaac tatcacctat gtattttttt atgatttcct ctctaatttc ttttaaattt
    19441 agcaatatta gtacctgcta cttacatagt agcttttcct ttccttttaa tactattatt
    19501 catttttgaa tcttatttag atatatttta agattaaaag tctttagcta tataattttt
    19561 tacccatttt taacttatat taacatatta caggcttata tctccaccct gtttacattg
    19621 aggatggagt atattgccta ttttgataaa aatgataggt tgctatttgc ctattccttt
    19681 ttctgataat ttttctaaca tatctttggt cattttatct aaatcataac taaacttaaa
    19741 gttccattct tttactgcac tactactgtc tagagagtta ggccaagaat cagctatact
    19801 ttgtcttaca gggtctacat catattctat cacaaaatca ggaatatatt tttttataga
    19861 atcagctatt tcctcaggag aaaagctcat agcagtaata ttaaaagcat ttctatggat
    19921 gagtttatca gctggagctt cgattaaatc cactattgat tgaagtgcat caggcatata
    19981 catcatatcc atttttgtac cttctgctat gtaagattta tatctcttat tttttaatgc
    20041 ctcataatat atatcaactg cataatctgt agttcctcca ccaggaggcg taacataaga
    20101 aataagacct ggaaatctaa cacctctagt gtctactcca aattttgagt gataataatc
    20161 acatagtaat tctccagaaa ctttagtcac accatacata gtattaggtc tttgtaatgt
    20221 atcttgagga gtcatatttt ttggagaatt ttcaccaaaa gcagcaattg aactaggtgt
    20281 aaaaaattta caatccaatt ctttggctat ttcaagacca tttattaatc cattcatatt
    20341 taagttccaa gcttctagag gtttactttc agcaactgca gaaagtaaag atgctagatg
    20401 aattatagta tctacatcat atttttttgc aatttcaaaa aaacgattct tatctgtaac
    20461 atctaatatc tcaaatatac cagattcaca tactggatta ccttctttta ctctccttga
    20521 actagcgatt acattttgtt ctccatactc atttctaagc tttattgtta attctgaacc
    20581 tatttgtcct aatgcacctg ttataagtat ttttttcaat tttacaacct cctaagggtt
    20641 taatttatgt agtactactt atttttattt tagcaaatct tttgtttaaa tacaaagaat
    20701 taaagataat aatatacgac ttaattgaat gaagtgcagt aagtgcctaa aaatttaaag
    20761 ctaatatata atggtatatt gtataacaat aaaagagtag attaaattat tatatataga
    20821 ttgtgtgact aagtcacaga aaatagagtt aatttaatat ataataaaag catatcaagt
    20881 aaagctttaa attaaagtaa ctttataaat aaaaagtaat ataaattgat aaaattataa
    20941 atttatttat agtgaatatg ggttggattt tatagataca aaaatagtat atatgatatg
    21001 tagaccatta gcaggtttaa agtagcaaaa catataaaat aaaatttgaa aggaagtata
    21061 aaaatgacaa gaccatcaat atatcatagc caaggataca cttgtgcaga ggcattaata
    21121 aagtcttata atgaggaaca taacacagat ataccaatct caataggaag tggtatgggg
    21181 gttggaatga atgttggaag tgtttgtgga gctgtaaatg ctgctgttgt tataataggg
    21241 tatttaaatg ggcgaaatag taatttagat gaaaatatag caaggaagta ttcaagagag
    21301 ctattgaata gagtaagaaa taaatacagc tcagaaatat gtgtatctct taaaaaaaat
    21361 aaagtaactt gtgaagaaat aataaatttc acatatgatg ctctaaatga tatgctaaaa
    21421 aatcaaaaat aattctaaga aacaagtatt ttacattcga tagaatactt gtttttttat
    21481 gatattttta ataagtatta gtttattata atttttaaat caattttatt atattttaat
    21541 tgaaacaatc tactttgaaa attactaact gacaaaagaa tatgattata gtatagaaaa
    21601 aatgtaaatt atttaatatt aagtgagagt atatgtttac ctatataaaa tcgtataaat
    21661 taatggctaa atttataaaa tataaagaaa tatataggaa aacaaaagaa ttaattagta
    21721 taatataaag tttaaaagtt aaaatttata taatttattt ataaagtaaa gaaaaaatag
    21781 aaatttgtaa taaaataaaa agtttatgac ataatatggt ataattagta aaaatataga
    21841 gattggagga attgctttgt ttatagatga agaattagaa ggttatatat taacatgtaa
    21901 aatatctgaa gactttaaaa atatacctga atatagtgat gaagagtttt atgttacagt
    21961 ctataaagat gaaagttctg actctgggta ctatgcttta ttagaaaata aagaagaaag
    22021 agttgtatgg gatggagaag ttgttgccaa taatattttt aataaccttt ggattgtagt
    22081 aaataaggtt aaaactggat aatagtctaa ttatatagta tttgtaatat tttaaatgaa
    22141 tttttacata tttgagatga gtaaataaca aagattattc gatactggag gagtaattca
    22201 atggaatata gttatagtaa gatgaactta aaaaaagggg atattgtaga ggtaaattta
    22261 gagaaacaag ccaatgtaat attgttagac catataaatt atgtgaaatt taaaaatcaa
    22321 agaaattatg attactatgg tggatttgca aagaaaaatc catgtagaat gagagttcct
    22381 aatactggaa catggtatct agtagtaaat caagatggaa atagtggaat agtaaacttt
    22441 tcaatcaata caattcaaaa ttaattttag aatattggat attcttaatt tttgtacatt
    22501 ttatatagtt aaaataaaat taataagcaa ttattataaa ataatgtggg tgcctcaaaa
    22561 tgaattttat aattcatgag acactctttt ttatatgaac tcaaatatac tttatcattt
    22621 caacaatgaa aaagaggcgt atctgtgttt tgagatagcc tcatttatca tatatcatat
    22681 atagaatttt aattattctt aactaaaatt ttttccatag gttatctgta caattaaaat
    22741 atttattgtt agcatacagc tccacctgta aggtgtaaaa gagcctctag tatctcttct
    22801 tttctttcca aaacttcatc tgataaaagc atttctataa atttatcagc accgattcta
    22861 tcgatagtta ttccaaaacg ttcacctgtg ttaccctgtt ctctaaataa aagaattgct
    22921 ttttcaatta aagtcataag ttcctctttt gaaaataatc tatcaatctg tgttccagga
    22981 cgaactgatt ttccccattt ccctcctata tagactttat aaccagattc tttttcttca
    23041 atactatcaa aattacaact ttctatacac ttaccacagt tattacatag attactatct
    23101 atttcaagtt tacctttatc tgttaattta gctgctttaa caggacagac ctctacaaca
    23161 gcacattttt tacaaccaac acaaagctct gaatcatagt caggtacacg ttgaccaaca
    23221 attccaagat cgtttaggtc aggtttaata cagttattag ggcatccacc aacaccaatt
    23281 ttgaacttat gaggtagttt tacatcatac caatttttgt aaaattcttc atgtatttca
    23341 gcagcaagtg cctgtgtatt agctagacca tgaacacaaa cagtaccttt acaagccaca
    23401 acaggacgaa cccttgatcc agttccacct gttattagat tttcgctagc aataaattca
    23461 cttagagctt caatatcttc aaattttaca ccaggtaatt ctactgttag tctagtagta
    23521 aatgctaact gaccgtttcc gaatttttca gcagcttctg caattttttt tgcttgtgat
    23581 gcatttatta caccatttac agttattata cgtgctgcaa aatgttctcc atccctgctt
    23641 ggtagaaaac ctctaccttt tacttccttt ttttgttctg ctgtaacatt actcatattt
    23701 actcctccat taccttaaga tttggataaa atagtattcc accttcaaga actttcgtat
    23761 ttgtatagcc aaagcgtctt aagcgatttt gcgccatata gctattttta cctttagcac
    23821 atataagaag aattttttca tccttagcaa gaccttcaat ttctccatta atttcaccaa
    23881 caggaatata acgtaaacta ggaatagaag gagcttttga aacatcaagt ttagtccaac
    23941 tgtcaaaatc ctcaatttcg tcaagtaaaa cactatcaag ttctccatta agtttatttt
    24001 gtaaaacatt tactgccact acaaaagggt gaatagctgt tgaaaaaggt ggtgcatatg
    24061 caaggtccat actttctaat gaataaaggt cagcgcctaa agttattgca gtagcagcga
    24121 tatctactat tttatcaacc gctccaggtc ccataacttg aacacctaat aattttctag
    24181 tatttttttc agcaaccatt cttataataa aattagatgc acctggataa taatgagctt
    24241 tatcatcagt agctatggtt acagagcaaa cattataacc ttctttttca gctatttctt
    24301 tacttagacc tgtttttcct gcattgagct caggtaattt tactactgtt gttccaagaa
    24361 caccattgta agttttagat tttccagata tattttgtgc gcaaattcta ccctcatgat
    24421 ttgcagatga ccccataggt gaccatgtag gtttatttgt taaagaattt tttacaaaag
    24481 cacagtctcc aactacatat atatctttgt catttgtaag catatattca tctgcaataa
    24541 ttgtattatt aggggcaaat tctaaacctg tgtcttttag aaaacctgtg ttaggacgga
    24601 ttccaactga cataaccact aaatctgttt taatagctct atttttagta cgaagttttt
    24661 caactttatt ttcaccttca atacctacaa cctggtcacc tgtaaaaatc attatgcctt
    24721 tatcagccat atgattttca acgtattcag caaaatcagt atcaaatcca ggcataacat
    24781 gttcagccat atcaacaaca cttacacgta tacccattgc agaaagattt tcagcaattt
    24841 caagaccaat gaaacctcca ccaataacaa cagctctctt aataccgttt tcaatagaat
    24901 ctcttagttt tatagcatca tttggagtac gcataaagaa tactccaggt aaatctattc
    24961 caggtattgg tggttttatt gggtctgccc ctgtagcaat tacaagtttg tcatagctta
    25021 gattttcttt ttctcctgtt gaaagcgttt tcaaagttac ttgttttgca tttctatcaa
    25081 tagatgtaac ttcaactcca caacgaactt ctgctcctgt tagtttagaa aaactttcag
    25141 gtgtatttac gattaaagat gatttatctt caattatctt accaacgtaa tatggaagac
    25201 cacaacctgc ataagaaata tcatcacctt tatttagtat tgtaacagag caattatcac
    25261 ccatttcacg ttttattttt gcagcagttt ttgttccagc agcaactcca cctataatta
    25321 atactttcac aatatatcac actccaatct actttataac tctataataa aattatactt
    25381 cttgacaata tatttgtaaa atactaaaat attaataaaa tcataagcat ttactaatgt
    25441 ttgctaaggt tgtgataata tgacaattcg tagtcttgaa atctttgtta aggttgctga
    25501 atgtggtaaa atgagtgaag tagcaagaaa tatgtatatt acccagtcat cagttagcca
    25561 agctatttca gaaatagaaa aagagtatgg tgttaagcta tttgatagaa tttcaaaaaa
    25621 attatattta actgaggcag ggaaaaaact tcttggatat gggaggcatc ttttagctgt
    25681 aaatgaagaa atgaatgatt gtatgaagca ttgtgcaaaa aatatccgta taagagttgg
    25741 ggcaacagta actgttggta catgtgtaat aagtccaata atgttagaat tatacaaggt
    25801 aaatcctctt atagaacctg aagtatttgt agaagataca agactgattg caaaaaaatt
    25861 acttaatagt gaattagata ttgcgattgt agaaggaaaa attaagcacc cagatattgt
    25921 tacaaaaagc attattaatg ataatcttgt acttatatgt tcacacaagc atgagtttta
    25981 taaaagagac tctataaaag tttcagaact ttcaaatcaa ccattaatta tgcgtgaatt
    26041 gggaagtggt acaagagcac aattagaaaa gcaattaaaa gaattaaaaa tcccaatgaa
    26101 tattagatgg tcatgttata actctgaagc tatattaaga gcagttgtag ataattttgg
    26161 cattgcagtt atatccgaat tacttattga ggattattta aaaaagcatc ttttgtgggc
    26221 ttgtgatatt gaaggtatta atttacatag gacatttgat attgcatatc atagaagcaa
    26281 gttttttaca gaaaatattt cagcattttt tgatatttca gtagaatatg ggaaaaaaca
    26341 agcgagaaag aagagtagaa gtgtaaacag tttataatat atctaaataa aaataagagt
    26401 atatcaatat actcttattt ttatttagat atattagcct atattaacgc caaaattttt
    26461 acacaatcct gcaagtccat cctcaaatcc agaacctaaa gcattaaatt tccactctcc
    26521 attatgtcta tatagttctg ccacaactat tgctgtttct atgctaaaat cttcacccaa
    26581 ttcatattta ataagttcct cattagtttc ttcattatat attcttatat atgaattttc
    26641 aacttgtccg aaattttgtc ttcttgtaat tgcttcattt atagtaacac taaatgatat
    26701 tttagcaata ttttgaggta ttttagataa gtctacattt atttgttcat catcaccatc
    26761 accaacacct gttctattat cacccatata ttcaacagct ccagaagcgt gttttaaatt
    26821 attatagaat ataaagtctc catcattcgt tacttttcca tcagttccag ttaaaaatgc
    26881 agaggcatct aaatcgaaat caaagccacc atcatattta ttaatatccc atcctagtcc
    26941 tactattact ttttttagac cagggttact ttttgttaaa cttacttttt gtccttttgc
    27001 taaagttata cccatttaaa ccaactcctc attataaatt ttttattgta attattactt
    27061 atatgtatta attaattcac gaagctcttc attttgacca attcctaaag cattaaattt
    27121 ccattcttca tttctacgat aaatttctcc tgccaaaact gttactttac cagaaaagtc
    27181 ttcttgaaga ttatatttaa ataattcttg cttggaattt gaatcaatta atcttataaa
    27241 agagttgttt atttgaccaa aatcctggtc tcttttttta gctttgtata tagaaactcc
    27301 aaaaactatt ttatgtacat attcaggtat gtcttctaaa ttaacaatta tttgttcatc
    27361 atcaccttca ccttttccag ttaagttatc tccagtgtgt ataatagctt tagaagggtg
    27421 tttaagattt ccaaaataaa ccaagtcacc tctaacattc attttatctt ggttagtcaa
    27481 tgctattgca aatgcatcta ggtcataatt ttttttaccc aatttattca tatcccatcc
    27541 taagcctact actagatttt ttacaggatt attatctttt actaagctaa ctctttgtcc
    27601 tttttgtaaa ctaacactca ttttaagttc tcctttttat atttttagtt ttattgatgg
    27661 tatcaagtat aagaaccata ttagctatat tatatacgta tttaggctaa gttggctata
    27721 tttataaatt atttattata taactacatg aatattttat aatttaaaca tattgacatt
    27781 atatgcttta aattattttg tagttttata atatttaaat ttgtatttga ttgttataaa
    27841 gtaaagtaag taataaagtt agactcaata attctaaaat ttctaagcat actatctaaa
    27901 tgagaacgga tttggaaata cttgtataaa acaataattg atacatttaa tttttatctt
    27961 aaaaacaaca attataatat ataaatagca agtataatat ataaatagca agtataatat
    28021 aacatataaa aagttgaatt tgtatatgtt aattatactt gctatttatt tgttagttat
    28081 tctatttttt taaatccatt acctaaagct tcatgtatat ctgtaattat aataaaagca
    28141 ttagggtcga cattttttac taattttttc aattcgacaa cttctttctt ttcaactact
    28201 actaaaagta catttttatt ttctccagta tatgcacctt ctccttttag aatagttgca
    28261 cctctatcta aatcttccat tattttttta cttatatctt ttgaaaggtc agatataata
    28321 gtgaatgatt tggaataatt aaatccttca ataagcaagt cactaacttt tactaaaatg
    28381 tataaagcca cagttgaata aagtgcaatt tcaacctgtc tatttactat acctgataaa
    28441 acaactacaa cgcagtctac aatacccatt aaaacaggta tactaaatgt aggaaaatat
    28501 ttatttagta ggagtgccat taaatcagtt ccacctgtag agccatttat tctaaaaata
    28561 agtccttgac caactcccat taaaatagaa ccagatataa ttgcaagata catatcattt
    28621 gttatatcta atgtagccat atttgcagta agcttaagtg ctatggtaag aaaaattatt
    28681 cctaaaaccg ttttaaaaca atcttttttt gaaagtattt tgtaagcaaa tatgaataat
    28741 ggaacattta aaagtaaatt gacaatccaa agttctacac cgaataatga atttaaaaca
    28801 actccaagtc ctgttatacc accagcagcg attgcatgtg gattaaaaaa taagttaaga
    28861 gaaatggcca ttaatataca gcctacaatt aatattaaaa tttctgaaaa agttattcta
    28921 tcttttttca ataacatcac tccttatata tagattataa tatatattat atagtttttc
    28981 caatttttaa taaaagaaat aaaaatatat tataaaaaca atttgattgg aattttcaga
    29041 aaattaatgc tataattaaa agtaaattta aagggaggtt ataaaatggc taaattaact
    29101 ctagaacata taaaaggaaa tacatattat attccactcc ctacaatagt aggtgtatac
    29161 gtagatggta aggatgcaat tttaattgac agtggaaata ataaggatac agctagacaa
    29221 gttttaagat tattagaaga acataattta aatcctaaat taataataaa cactcattca
    29281 aatgcagacc atataggagg aaatgcatat ttgaagaatc aaacaaaatg caagattgct
    29341 acgactaaaa ttgaaggata ttttacagaa aatccaatat tagaatcagc atttttatat
    29401 ggtggctatc caagtaaagc actgaagaat aaatttttat tagcaaagga aagtgaagtt
    29461 gattatatta tcccttcaaa tggcaaaatt gtagatacag aacttgaagc gatttctctt
    29521 ccaggtcatt attttgaaat gattggtgtt agaactccag ataatgtttt gtttgttgca
    29581 gatagtctta caccagagaa tataattact aaatatcatt ttttcttcct actggatata
    29641 gattcacagt ttaagacact agaaaaattg agaatgttag aggctgattt ctttgttcca
    29701 agtcactctg tcaaaactac agatataaaa agtttaatta atattaataa gaagaagatg
    29761 gaagaaataa tagataatat taaaaaggtt tgttatgagc cagttatgat tgatgaagtt
    29821 attgaaaaaa tgtgtgattt gtacaatgtc aagcttgatg ctaatcaata tgtgttggtt
    29881 ggaagtacaa tacgttctta tataacttat ttatatgaga ataatatggt tgaatatata
    29941 tttgatggtg gtaagatgat gataaaagct gtgtaaatag taataatttt caaattatat
    30001 gatgaaattg ttttagtatg actgttattt gaaaagtaat ataaaaaaat ttatataaat
    30061 aagctaagat gattgatata aagttactga taattttaag gtaatatata cgttactata
    30121 atattatgtt attatttgta aataagggga taatttataa gcaaattaaa gaccttaatt
    30181 tacaggagga atagtgtata ttatgaataa aaaattcaaa aaattcagta aaaaactaag
    30241 tatattaatt ttagttttga ttatgtttct ttttaataat ttaactgcaa atgcacagat
    30301 taaagaagat tcaataatag gaattgatag atatgaaaca gcaggactta tagcagatag
    30361 acaaacttat gatactgtaa tattagttaa tggagataaa aatttatctg atgggctttc
    30421 atcaagtgga ttagctggag ctattaacgc accaatactt ttgactaaaa aaagtgaaat
    30481 accaaaagct actttaaata gactagataa taagagttta aatgttgtaa aaaaagtata
    30541 tataattggt ggttataata ctattgaaaa ttcagtagaa aaagatataa aaagaaaagg
    30601 tattcaagtg gaaagaataa atggtaacaa tagaattgaa actagttata atgtagctaa
    30661 aaaaataaat gaagtaagta gtgtaaaaga ggtaatgctt acaaatggat ttgtaggaga
    30721 ggctgatgct atgagtatag cacctgtagt tgcaaaaaat aaaggagcta taatacttac
    30781 agatgggaaa tcagttccat ttaagactga aagtttaaat gtttacgcta taggtggcaa
    30841 atctgcgata aatgaggatt tagtaaatga aactaaagca actagaatcg gaggaaatga
    30901 tagatttgag accaataaaa aggtaatgga aaagttttat aatggagcga cagattttta
    30961 tataacaaat ggatatcaat tagtagatgc actaacatta tctcctttag ccaaagaaaa
    31021 accaatcgtt ttagttgctg atggaagtaa taaaggtatt ttaaaaggag ctaaaagtat
    31081 aacaaaagtt ggaggtattg atgccaatat atataaacag tgtttagata tgattaaata
    31141 taataatatg gatatgactc caaatatttt aaaacactta acttcagttg aaggaaatga
    31201 agtttctgaa atacttatag aatcagataa tttaggtgtg gttgttgaaa agacgaatac
    31261 caataaattt gagtttgatt acgtaagtgt aactaatgaa aaaaattgta ctttttctgt
    31321 atataaagaa aattcttcta ataatataaa aaatggaaag ctagttgtaa gtgctaagaa
    31381 aaaaatagat aagaaagata gtgatttgca agatatgaat ggcgacaata tgataaatgc
    31441 aaataaagat aggatggtaa atgtgataaa aattggagtt cccgataaaa tgtattctaa
    31501 ttttaaagta gatgttgaaa gtggttcagt agaactttat aatattaaag gaggagctac
    31561 tgttgatgtc aatgacggga ttgctaacat tgttgataac aatgtaacaa atcctttcaa
    31621 tataaatact aatagtggga tttcaggtgt aacagctgaa actatatcat ctgaaataaa
    31681 atttagagca aacaatggaa ttgtaaatgt aacagctacg aatataaatg gcaatataag
    31741 tttatttgga agcgataata aaggtacctt tgatggaata tttaaattaa atctgaaaaa
    31801 agaaccatca aatttacact tgaagttaat tggaaatggg ataaataaat tgccagaagg
    31861 ttggtctaaa gattatattt taggaaatgg acaaccaatt attgaagtta aaaataatgg
    31921 cataaataat atatcaattg gagaataaaa acatatgaaa ataaagttta ta
//
LOCUS       DAEHWO010000044        31550 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEHWO010000044 DAEHWO010000000
VERSION     DAEHWO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31550
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.044"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            136..678
                     /locus_tag="KNP54_002348"
     CDS             136..678
                     /locus_tag="KNP54_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0893245.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            1006..2499
                     /locus_tag="KNP54_002349"
     CDS             1006..2499
                     /locus_tag="KNP54_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBF0893246.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2573..2806
                     /locus_tag="KNP54_002350"
     CDS             2573..2806
                     /locus_tag="KNP54_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893247.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2962..3726
                     /locus_tag="KNP54_002351"
     CDS             2962..3726
                     /locus_tag="KNP54_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0893248.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIINFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4011..7190)
                     /locus_tag="KNP54_002352"
     CDS             complement(4011..7190)
                     /locus_tag="KNP54_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBF0893249.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGINKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLDKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7471..9648
                     /locus_tag="KNP54_002353"
     CDS             7471..9648
                     /locus_tag="KNP54_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBF0893250.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYKQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEANCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9662..10084
                     /locus_tag="KNP54_002354"
     CDS             9662..10084
                     /locus_tag="KNP54_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0893251.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10258..10833
                     /locus_tag="KNP54_002355"
     CDS             10258..10833
                     /locus_tag="KNP54_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0893252.1"
                     /translation="MVKVLAFMGSPRKKGNVDTILDEIIKGVNDNNVEVKKYYLNDMN
                     IKGCQGCLYCRKVPTCAFKDDMIDIYEDIKSAEYIIIGSPVYICQVSAQTKLLLDRLY
                     PLTEINKSKHIPRFGQKKLIMVYTQAAPISFLFKKYFKYTAKHLKGMGLNHYKTIVVT
                     KAFERNSTKKNFKVLKKAYKLGMKIAIDING"
     gene            complement(10958..11674)
                     /locus_tag="KNP54_002356"
     CDS             complement(10958..11674)
                     /locus_tag="KNP54_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBF0893253.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFQNKLDI"
     gene            11839..12564
                     /locus_tag="KNP54_002357"
     CDS             11839..12564
                     /locus_tag="KNP54_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0893254.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASFLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            12624..14216
                     /gene="hcp"
                     /locus_tag="KNP54_002358"
                     /gene_synonym="priS"
     CDS             12624..14216
                     /gene="hcp"
                     /locus_tag="KNP54_002358"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBF0893255.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            14588..15493
                     /locus_tag="KNP54_002359"
     CDS             14588..15493
                     /locus_tag="KNP54_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBF0893256.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            15617..16570
                     /gene="msrA"
                     /locus_tag="KNP54_002360"
     CDS             15617..16570
                     /gene="msrA"
                     /locus_tag="KNP54_002360"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBF0893257.1"
                     /translation="MIKLATFSGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            16723..17853
                     /locus_tag="KNP54_002361"
     CDS             16723..17853
                     /locus_tag="KNP54_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0893258.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(17970..18938)
                     /locus_tag="KNP54_002362"
     CDS             complement(17970..18938)
                     /locus_tag="KNP54_002362"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBF0893259.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            19273..19461
                     /locus_tag="KNP54_002363"
     CDS             19273..19461
                     /locus_tag="KNP54_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893260.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            19721..20920
                     /locus_tag="KNP54_002364"
     CDS             19721..20920
                     /locus_tag="KNP54_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBF0893261.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            20972..21475
                     /locus_tag="KNP54_002365"
     CDS             20972..21475
                     /locus_tag="KNP54_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0893262.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVVHS"
     gene            21582..21899
                     /locus_tag="KNP54_002366"
     CDS             21582..21899
                     /locus_tag="KNP54_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893263.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            22057..23016
                     /locus_tag="KNP54_002367"
     CDS             22057..23016
                     /locus_tag="KNP54_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBF0893264.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            23131..23916
                     /locus_tag="KNP54_002368"
     CDS             23131..23916
                     /locus_tag="KNP54_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893265.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            24208..25527
                     /locus_tag="KNP54_002369"
     CDS             24208..25527
                     /locus_tag="KNP54_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBF0893266.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(25602..26030)
                     /locus_tag="KNP54_002370"
     CDS             complement(25602..26030)
                     /locus_tag="KNP54_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893267.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(26121..27497)
                     /gene="hydG"
                     /locus_tag="KNP54_002371"
     CDS             complement(26121..27497)
                     /gene="hydG"
                     /locus_tag="KNP54_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBF0893268.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(27498..28583)
                     /gene="hydE"
                     /locus_tag="KNP54_002372"
     CDS             complement(27498..28583)
                     /gene="hydE"
                     /locus_tag="KNP54_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBF0893269.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(28619..29827)
                     /gene="hydF"
                     /locus_tag="KNP54_002373"
     CDS             complement(28619..29827)
                     /gene="hydF"
                     /locus_tag="KNP54_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBF0893270.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTQKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(29842..30093)
                     /locus_tag="KNP54_002374"
     CDS             complement(29842..30093)
                     /locus_tag="KNP54_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBF0893271.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(30474..31514)
                     /locus_tag="KNP54_002375"
     CDS             complement(30474..31514)
                     /locus_tag="KNP54_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBF0893272.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLSLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT        11947 a         3674 c         4967 g        10962 t
ORIGIN      
        1 aagacaaata tgttaaaaaa atgataatca cggagaactt ttaccttctt caattaatat
       61 attattatta gtaataactt taaaattata ttactattat ataaaaattg gcttaaaaga
      121 aggtgaaaaa agtaaatgaa aatatgcata acagtaggtc atagtatact aaaaggtggt
      181 aaaagtacag gtgtaaatgg tatagttgat gaatacaatt ataataaaaa attagctcct
      241 atgttagctg agatgcttat aagtcaaggt aatacagtag atgtaataat ttgtccagaa
      301 aggcacttta tgtcagaaag agaagaattt ttctatagag ttccaaaagt aaacagtggt
      361 aaatacgatt tattagtaga gctacattta aataaagctg atggaacaca atgtggtaca
      421 gaagtgcttt actatggcac tgaaggatta gaatatgcta aaagagtatc taatagactt
      481 ggagaattat ttgaaaatag aggagctaaa aaaagagaaa atttatatat attgagaaat
      541 acaaatccag ttgcaataca gattgaaagt tttttctgtg ataatgtgaa tgattgtaac
      601 aaagcaaatg aatcaggtta tgattatata gcacgattga ttacagaagg tatattgaat
      661 aaagatataa atatgtgaga ttatggtgat ttaggtattg attaatacct tttaatatta
      721 gatataaata aaaatacaat gtattagtat aatttaaact ttcaaaagat agattagttt
      781 gattattgac aagagatacc tccttgaaaa tattgattta tcagtatatt taaggaggta
      841 tttaaatata aaaatttaat taatttgcta ctaaactata ggtttataga gtatatactt
      901 ttatcttcag tctaataaat aatataaaaa tagtagaacc ttgtattata ataatataat
      961 gtagaaaaat atatagataa gataaatata ataaggtggt aatatatgaa atatacattt
     1021 gaaaaattta agttaaatga aaagatactt aagtcattga agagtttagg atataatata
     1081 ccttctagag tacaaagaga agttattcca aaattattaa aaggtcaaaa cttagtagtt
     1141 aggtcaaaaa caggaagtgg aaagacagca agttttgcaa tacctttatg cgagaatata
     1201 aatgtagatt acaataatat tcaagctctt atagtggttc caacaagaga attagccttg
     1261 caagtaaaag atgagatatc agatataggg agactaaaga aggtgagatg tagtgctata
     1321 tttggcaaac aatctataaa agaccaaata gctgaattga aacaaagggt tcatattgtt
     1381 gtagctactc caggcagaat acttgaccat ataaatagag gttctattaa gttggaaaat
     1441 gtaaagtatt tagtaataga tgaggcagat aaaatgttta ataaaggttt tgttgaacaa
     1501 atggaaaaaa tattattaaa tttacctaag gagaaaatag taagtctttt ttcagctaca
     1561 atagatgaag agataaaata tatatgtgaa aaatatatgc tagattacag tgttataaat
     1621 atagaagaaa atgagagcga tactaatcaa aaaacaagac aaatagatga caaaataatc
     1681 aaggcaaatg gaagagagaa gtacatcctt ttaaaagaat taatatacag cgaaaatcca
     1741 aagagtgtga taatattttg taataccaaa gagaaagtat ctaaattata taacaagatg
     1801 agtaaagagg gttttttaat aagagagtta catgcagatt tatcacaaga aagaagaatt
     1861 tttgtaatta aggattttaa aaaccaaaaa tttaatatat tagttagtag tgatgtagcg
     1921 tccagaggaa tacatattga tgatatttct ttagtaataa attatgatgt gccacaagat
     1981 aaagaaaact atatacatag aataggtaga actgggagaa aaggaaatag tggaaaggca
     2041 attactatag taactgaaaa ggatgaaaaa tatatagaga atatagaaac gtatatagga
     2101 tataaaataa atgaattaaa agatatagaa aaaagtagaa ttacacatgg caaagttttg
     2161 tttgaagaat attcaaaagg aatcctaaaa aaagtatcaa agagaaaaaa agttgataaa
     2221 aattcttaca aaagtaaaga tataaaacta aatatagaaa gtgaagttgt taaattatat
     2281 ttaaatgctg gtaagaagaa gaaaataaga gttttagata tagttggtgc atttagtaat
     2341 ataaaaggta taactaatga tgatataggt gtaattgaag ttcaagattt atgttcatat
     2401 gtagatatat taaattataa gggagatttg atattaaaaa aatataagga gatacctata
     2461 aagaaaaaaa tggttaaagt gaaaagagat atacgataat ttagtcaata ttgatgaatt
     2521 gctttgttat cgaaatgaag ttgcaaaaaa cacaatagaa gttgttaagg atttgaaagc
     2581 tgaagatatg aaacgaaagg tctctccaat tgacttagaa aggattttgg tgactggagg
     2641 agtaataaag catgaagatt ctatttggtt gttggacttt tgggggaata aagatattgc
     2701 tggaattttg cttatgcctc ctactcgtca tgttatactt catttgaatg attgttgtaa
     2761 atggaaggaa tattttcgta caaaaaagaa attttacaga agttaaatta taataaatta
     2821 gacaaacaat agataaatta gcaaggaatg ttgattttat ctacattcta agttatacta
     2881 tttttaagtg gctaagggaa tagtcatttt aaatataagt aataaatata tacctatagg
     2941 gatattaaag gggggaaata tatggcatat tttaactata acgacaaaca gtgctactat
     3001 aatgaaattg gggatggtac accattactt tttttacatg gaaatacagc ctcttccaag
     3061 atgtttaatg atataatcaa tttttataaa gatgaatata aagtaatatt aattgatttt
     3121 gtaggtcatg gaaaatctca aatggtcgat aaattttctg ctgacttatg gtttgatgag
     3181 gctatgcaag tgatatgttt tttagaagca atgaactata aaaaagtaaa cataattggt
     3241 agtagtggag gagctcttgt tgcattaaat gttgcacttg agagacctga tttagtgaat
     3301 aaggtaattg cagatagttt tgaaggagaa gttcctctag agtcatttgt acaaaatgtg
     3361 aaaatagagc gtgaagcatc taagcaagat gatggtgcaa aagcttttta tatttataat
     3421 caaggagaaa actgggaaaa agttgtagat aatgatacag aagctatttt tgaacattat
     3481 aaaactatag gaaagttttt tcataagcct ctagaaacta tgcaaccaga ggtgctttta
     3541 acaggaagta gagaagatga gtttgtatct ctaatatcta gtgatttttt tgaaaatact
     3601 ttttcattac ttcttgaaaa gattaaaaat ggtaaaatgt atttgtttga taaaggtggt
     3661 catcctgcaa ttttatcgaa tggattagat ttttcaaatg tagcaaagaa atttttagag
     3721 gaataattta accaaaattt acaataatga aaactgtaaa atggattgca aaacttacaa
     3781 aagtgagtgt acatatactt cattattatg atgaaatagg attgttaaaa caaaatattc
     3841 taatagtcaa gttattacat ttgtatatgc aatatgtata gaaagagata tcattagatt
     3901 gtaaagttgg gattaaataa caatattaaa ttttatttat tcagatattt tagcttaact
     3961 atataaatgt tagaacaaat tcatatagtt aagctgtagg attaaataat ttagttaaat
     4021 aagtttatta tctcctcatc agatagactt tttaatacac cttcattaga aagttctcca
     4081 tttataaatt gatttataag ctctttttta ctttcttgta attttattat tttttcttct
     4141 atagtccctt tagcaatcaa ttttataact tgtactgaat ttttttgacc aaatctatga
     4201 gctctatcac tagcttgatt ttctactgat ggattccacc atgggtcaaa gtgaattacc
     4261 atgtcagcag atgtaagatt taaaccagtt ccgcctgctt ttaaagatat taaaaaaact
     4321 tttttatcca tactattatt gaactcatct acaagttcaa gtctttcttt ggcattagtt
     4381 ttaccatcta tataatggta tttaatttta tacttatcaa gttccttact tatgttctta
     4441 agcacagaag taaattgtga aaacaataat attttgtggt tttcgtttat actatcccta
     4501 agtatttcta aacatgtttc aatttttgaa ctttttttat tgtaatcttt tactactata
     4561 cttgggtcta aacaaagttg tcttagttta gttaaataag agaatataac tattttatct
     4621 ttctttagat ttttatcttt cattttatct tgtatatctt ttgaatatac actatatatc
     4681 tttttctgct ctttattcaa ttcaacaaaa aagttttttt caatcttatc tggaagttct
     4741 ttcataactt gttttttact tcttctaaga ataaaaggtt ttatcaattt tttcaggttt
     4801 ttaacattat cttctttatt tataaacaat tcctgaaact ttgctttact atatagatag
     4861 ccaggcatta taaaatcaaa tatagaccat aattctagta gattattttc cataggtgta
     4921 ccagtgagtg caaatttatt ttctgcattt atacttttta cagactcagt tactaaagcc
     4981 actggatttt ttatattttg agcttcgtct aatatacaat aatcaaactt tatttcacta
     5041 tatttgtcta aatcatttct aagagtacca tatgttgtaa gtattacatc aaaattttct
     5101 aattccataa aacatttttc tctatctctt ttatttccat gtatcaataa aacttttata
     5161 tctggagcaa acttttcaaa ttcatttttc caattataaa tgagtgatgt cggtgtaaca
     5221 ataagacttt ttttattaga taatgataat aaaaatgcaa tagtctgtat tgttttacca
     5281 agacccattt catcagctaa tataccacca aatttataat aatctaaaac tttaaaccaa
     5341 ttgaggccat ttatttgata gtcacgaagg tttgcattta aatttgcggg aatttctaaa
     5401 tttatgctat caaaatttct aaatttttca catatactgt ctagttcttt tttaccatct
     5461 ataaacttta aatttttact acgtattaca tcatttatat atagagcttt atttttatga
     5521 attttattat tttttgattt atccattata tctagatttt caactaattc aaaaaaatct
     5581 tttgtttctc tttctgataa atctataaag tttccatctt taagtttata aaaagtacgt
     5641 ttttcttgaa aagctttcaa aatatccttg tactcttttg gatttatatc agatatatta
     5701 aaattaaatt ctaggtaatt ctggttagtc tgattgattg aagcttgaat tgatgaagcg
     5761 ttatatattt ttttcaattt aaacttctca gaataatata tatctccaaa ttcctttaga
     5821 gattctaatt gtaaatctaa aaatgtaaat aggtcatggt cagttccttt aaacacataa
     5881 tgattatttt cctttgtaaa ttgtgaagaa gtaagtttat tttcaatagt agcttccttt
     5941 tgtatgttgg ggagcacaaa ttttttatct tcatcatcat atatatactt tacatcacaa
     6001 catatgttgc catcaatcat atcaaagtag aactcagatt taaaatcttt tgttatatta
     6061 ttttttatgt tatcatctaa atgaacttct tgagatatag attttaatct aggaactagc
     6121 aatcctaaaa catccttaga atcctcttta tcaaatttta actctttagt ctttgataat
     6181 atttgatata tttttgaata atcatgagct tttttatgtg ataataaata gatattgcca
     6241 tcatataaaa gtacatcatt ttttttagta agtggaacag gtagtgaatc tttagaatat
     6301 aagactattt tatcttctat atttttaaaa tcaaacctta caggtagagt atcatttaat
     6361 atctttggat gatattcctc tttagaaaaa ataagggtaa aatccttgta cttaatagca
     6421 tttaaaaatt gttttaaaga gcttgcattt atctccataa atttttttga atgtgatgaa
     6481 gaaaagttgt atgaaagatt tgtcccatat tcttctataa tatctactaa cttctcatct
     6541 tcatcagcaa aataatgagt gttggggttg taagtaaatt tcttcccaaa atctaattca
     6601 tatccattaa gttttgaata tgcaaattca gtaatgtttt ttaaaatgta cattttatta
     6661 attcctattt taaattcagc aattgcttta tttgaatcca catttatcaa tacatctaaa
     6721 ttaacccttt ctcttttagt attgtctaac aaagaaagta attgcttgct taaatctaag
     6781 ctggttttag aatttgtatt agaaagctta tccttatctg cacctaatat atctattaga
     6841 ataggaggaa catctttttt attttttatt tgttttaagc tttttatcac aatagcaact
     6901 atatgcttac atataaaaat acttttgccc tttgattgac agtcagcgca actacaatca
     6961 ttttcaatta tcttaaagtg ctttatatct atagttattg aattaaaata aaagctataa
     7021 ttatcttcag aattgactcc accacgaaat gtcaacagat tattttgtag gtcatcaata
     7081 tctatgtcta tataatcaac taattgatta gtataatatt ttacacctct tgaccatctt
     7141 gatggttctg tatttcttct tattagttta tatatcatat ctattttcat attattcacc
     7201 ttacctcact gtatatatta taatctaaat gcattcaatt tacactctaa atttaagact
     7261 aaaattaagg cagatatgaa tagcttttat ctatcacgat atatgtgtaa ataacaattt
     7321 actattagat ttttattgaa ttatcttata aactatgaat gaaaaataat tatataaata
     7381 gattattaat aaatataaaa tcttattatt aaaaatattc ttagaaatta cactgtataa
     7441 aatataaagt atgatatttg aataaaaaga atgtataata agtataataa tttgtattta
     7501 ttattgggaa aggaaaatgt taatatggat agttataaac aacttaaagc taaaataccc
     7561 tgtaaggaaa caggtataga aataaagagg actttatgtg atatttgttc gccaggagta
     7621 cattgtggaa ttgatgcata tgttaaagat ggtaaagtaa taaaaataga aggtacaaaa
     7681 gaacatccaa tgaataaagg gttgttatgt accaaaggtc tttgcaatag agaatatatc
     7741 tatagagaag atagaataaa aacacctcta aaaagaattg gaaaaagagg tgaaggaaaa
     7801 tttaaaccaa tatcatggga tgaagcttat agagaaatag cagaaaaatt aaatagagta
     7861 aaatctgagt atggagcaaa gcatgtagct ttttttacgg gttatggaaa gtggtataga
     7921 ccttttttac aaaggtttgc atcttcattt ggttcaccta attatggtac agaatctagt
     7981 tcatgttcaa catcagcaca gatggctgga aatgttgcta ctggaagaaa ctttacaatg
     8041 caagatatgg agaatgcaaa aacttattta gggtggggat ttaatccata ctactctaaa
     8101 tttttaaata gtgtgaatct aataaaatta aaagaaaaag gtctaaaatt tataattgta
     8161 gaccctagaa taacaccgac aactcaaaaa ctagcagatt tacatttaag aattaaacct
     8221 ggaactgatg gagctttagc tcttggaatg gcgaatctat ttatacaaaa ggatttaata
     8281 gatagagaat acatagaaaa gcatgtacat ggatttaatg aatataaaga atatgtaaaa
     8341 ttatttgatt tagatactgt aagtagaatt acaggagttt ctaaagataa tatagtaaaa
     8401 gctgttgaga tgttgtcaca aggtccattt tgtataaatg aaagtgcagc tccaatagtt
     8461 catcatcaaa atggatttca aaattataga gcaatgatgt ctttatccgc tataacaggt
     8521 aattatgata gaataggtgg aaacatacca aaacaagatt actttgctgg taagataggt
     8581 ggattccaaa cactagaaaa agagtttgta aaagaagttc tacctaaaaa tataaatgaa
     8641 agaattggtg gagaaagatt tcctctatgg aatgaaatgg tgactcaatt tcaagctatg
     8701 gatttaccta ggcaaataga agaaaagaca ccatatgaaa taagagcttt gttttgtcat
     8761 gggataaatg ctagaatgtt tcctaattca gggagacttt ttaaagcgtt gaatagtgta
     8821 gatttttttg tgaatataga tttatttatg acagatacat caaaatatgc agatatactt
     8881 ttacctgcat gtacatcatt tgagagagaa gaatgtaaga gttatccagg agggtatatt
     8941 acatatacca aaaaagttat tgataaatta tacgattcaa aatcagatgt agaaatactt
     9001 tcagatttag caaatgctat gaatatagat gatgatttat taaaagcagg ttatgaagca
     9061 agtgtaagac atatgtttaa aaatacatgt gtagatgtag ataaacttaa agaaagtgat
     9121 ttaccattaa aatgtaaaga ttttaagcca tatatagtag gttcatatac aagagaaggg
     9181 tatgatacta gcacttctag gtttgaatta aaatctacaa ttattgaaaa atataaagat
     9241 tttgggctgg atgcactacc aacatataga ggatttaatg ataatataga tgatgaatat
     9301 actcatttat tgacatcagg agcaagaatt tcaaatgcac tacattcaag acttcatgac
     9361 atcaaacttt caagaatatt aaaaaatgaa gctaattgtg atatttctag cttagatgca
     9421 aaagaattgg gtgttatcag tggagattat ataaaaataa ctactaagat aggaagtttg
     9481 gatgtaaaag tcaatgttac tgatagagtc ttatataaga atatacatat gtatcatgga
     9541 tatagagaag ctgatataaa tagtattatt tgtgataatt ttgaccctta tagtggattc
     9601 cctgcgtata gaagttgtaa gtgtaagatt gaaaaaatga atagataaat ggagagatat
     9661 aatgaaaagt ttatttaaat ttaataaaga attatgtaca gcatgtggag catgtttgct
     9721 tgcatgtata gaccaaaatg ataataatat agacaatggt gaacttttta gacatgtatt
     9781 tacaatagag gaaggtgaaa atatagaata tttttcatta gcatgtatac attgtaatga
     9841 gccaaaatgt ttaggtgtat gtcctaaaaa ttgttttaaa aaagaagaag gattcattgt
     9901 attagacaat caaaactgta tagggtgtaa actttgtgaa aaagcttgtg aatatggagc
     9961 cttaatttat ggaaatgatg gtaaggcaaa taagtgtaat ggttgtattg agagatataa
    10021 gtgtggtatg gattcacctt gtgtaatggt atgccctaca ggagcattaa aatttaataa
    10081 ataattgtat taaattgcta tactactttt aaataattgt gttaagaatt attttttgat
    10141 atacttttgt aatataaaat gtaaataaaa caaatacaaa gtatataaaa tatattttta
    10201 gaataaagtg tgctttagat taaatttaga aaaataaatt agacaggaga acttaatatg
    10261 gtaaaagtat tagcctttat gggcagtcca agaaaaaaag ggaatgtaga cacaatactt
    10321 gatgagataa taaaaggtgt aaatgataat aatgttgaag ttaaaaaata ttatctaaat
    10381 gatatgaata ttaaaggatg tcaaggctgt ctatactgta gaaaagttcc tacttgtgca
    10441 tttaaagacg atatgattga catatatgaa gatataaaaa gtgctgaata tataataatt
    10501 ggttcgccag tatatatatg tcaggtatca gctcaaacaa agctactttt agatagattg
    10561 tatcctttaa cagagataaa taagtctaaa catataccta ggtttggtca aaaaaagtta
    10621 atcatggtct atactcaagc agctcctatt tcgtttttat ttaaaaaata ttttaagtat
    10681 actgcaaaac atttaaaggg catgggatta aatcactaca aaactatagt tgtaaccaaa
    10741 gcatttgaaa gaaattccac taaaaaaaat tttaaggtat tgaaaaaagc ctataaactt
    10801 ggaatgaaaa tagccattga tatcaatgga tagataaaag tttaatttat agtatagcta
    10861 aaggagcatt aattattaat actccttttt tgtataaagg tttctagaaa ataactaata
    10921 aaaaacaata ttatttgaat acagatatta tacaagccta gatatctaac ttgttttgaa
    10981 aataaaagat ttcaaattta tttttgttaa aagataacaa gccttcatct cgcatcttgc
    11041 caagctctct tgacatagaa cttctgtcaa cacataaaaa atcagccatt tcatttcttg
    11101 aaaagggaat tgtaaactgg tggctacctg tttgttctat ctgttttgaa aaatacataa
    11161 gcaatttctc gcgagttgtt ttacgagaaa gtaattctat tttattgtga agtaaaatgt
    11221 ttttttcagc tattaattgt agcatatttt caacaagcct attatgaaat acacatgcag
    11281 atgaacaaat accagttaca cttttaaact ttataaataa aacttcgcaa gaagatgttg
    11341 tggttactgt aacattactt ttatgtagtc tagtacatgc gaatacctct ccaaataaat
    11401 ctccaggcaa gagttcagct acaatattcc tattcccttc gatatcttcc tttattatat
    11461 gagcacttcc tttaagcata attccaatag aagtaacttc acttccaaca gagaatatta
    11521 tactatcttt tgggtaagtc ttatctacaa cacctaaaca ttccaacatt tcttcaagtt
    11581 catcactttt aattccttca aatagaggaa tttttttaag taagtctata tgcttttcta
    11641 aaaatttttt caaataatca cttccttgtt gcatatgcaa ccgataattt gttttcattg
    11701 tactatacta agtttataaa agcaagggga tataaaaatc ctactacaag aaatttgaaa
    11761 taaagaaata taggtattaa aaataaatat ataagaaatc aatactttaa attaaaaaaa
    11821 ttttatgagg tgatataaat gatgagaaaa ataattaaaa ttgatgagga aaagtgtaat
    11881 ggttgtggac tatgtgttga agcttgtcat gaagaagcta taggaatggt aaatggaaaa
    11941 gcaaaacttt taagagatga ctattgtgat gggctgggag attgtctgcc aacttgtcca
    12001 acaaatgcga tttcatttga gtatagagaa gcagcagaat atgatgaagc tgcagtaaaa
    12061 gcaaatatgg aagcaaagaa agcacaaaag aaaactttag catgtggatg tccaggttct
    12121 cagtctaagt caataaatag agaggtttca aatagtacgt ctataagcaa tgatatagta
    12181 gagataaaag gttctcaact taatcaatgg ccagtacaaa taaaattagt accaactaat
    12241 gcatcatatt taaagaatgc aagtttttta atagcagcag actgtacagc gtatgcatat
    12301 ggaaattttc ataataaatt tatgaaaaat aaggttacat taatcggatg ccctaaactt
    12361 gatgaagttg actatgctga aaaacttaca gagattttaa aagaaaatga tattaaaaat
    12421 atagtagtaa cacgtatgga agttccttgc tgtggtggta tagtaaatgc tgttaagaca
    12481 gctctacaaa atagtggaaa aatgatacca tggcaaatag ttactatatc tgtagatgga
    12541 aaaattgtag atggagaaat ttaattaagt gaattataga aaaatataat aaattttaat
    12601 aaataaaaag ggaggaataa aaaatggaaa aaatgttttg ttttcaatgt gaacaaacag
    12661 caggaggtaa aggttgtact ataaatggtg tctgtggtaa aaaggggggt acagctaact
    12721 tacaagacga acttacagga gtgttgattg gtctttcaag agcaactatt ggaaataaga
    12781 atagaccaac aagtgaaaca gataaaatta tgatagaggg gctattcact actataacga
    12841 atgtaagttt tgatgatgaa gctataaaaa gacaaattga aaaaactgag gtagaaaaaa
    12901 gtaaacttgt acctagatgt tcagattgtt caacaacttg taatagaaat gataactatg
    12961 atatgaagga tttatggaat gataatgagg acatacgttc attaaaatca ttaatcttat
    13021 ttggattaag aggtatggct gcctatgcat atcatgcaat ggtacttggt tatacagaca
    13081 aagacgtaaa tgaatttttc tatgaaggat taatagcagt tggaggagac ttgtctattg
    13141 acgaactttt aggtctagtt atgaaaactg gagaaataaa cttaaaatgt atggaattgc
    13201 ttgatagagc aaatactgaa acttatggaa caccagaacc gactcaggta tctatgaaaa
    13261 tcgagaaagg gccatttatt gtagttacag gacatgacct ttatgattta cacaaattat
    13321 tagaacaaac gaaagataag ggtataaata tatatactca tggtgagtta ttaccagcac
    13381 atgcatatcc aaaactaaaa gaatataaac atctaaaagg taattttggt acagcatggc
    13441 aaaaccagca aaaagaattt gataatattc ctgctccaat attatttaca acaaactgtt
    13501 taatgcctgt taaagatagt tatagagata gagtatttac tacagaagta gttgcttatc
    13561 caggtatggt tcatattgat gaagataaag atttttctag tgtaatagaa aaagctcttg
    13621 aacttggagg atatagagaa gatgttcata tgactggtat taatggagga gatacattaa
    13681 ctactggttt tgcaagaggt acagtttcat ctgtacaaga taaagtagta gatgctgtaa
    13741 agagtggagc tataagacac tttttattgg ttggaggttg tgatggtgca aaacctggaa
    13801 gaaattatta cactgaattt gtaaaacaag ctcctaaaga cactgttata ttgacacttg
    13861 catgtggaaa atatagattt aatgatttag accttgggga tataggtggc ttacctcgtt
    13921 taatggatat gggacaatgt aatgatgctt atagtgcaat taaagtggca gtttcattgg
    13981 caaatgcttt tgaatgtgga gtaaatgatt tgcctcttag catggtactg tcatggtatg
    14041 agcagaaagc tgtttgtata cttcttacac tacttcattt aggtatcaaa aatatctata
    14101 tagggccttc tttgccagca ttcttatcta agaatgtatt agatatattg gttgataaat
    14161 ttgcattgac acctatatct actcctgaag aagatatgaa gaagatttta ggataaataa
    14221 acatatctat acttaaagat atttatagtt aaaatatttt taagtatgcc acaattaaga
    14281 taaggggtta aacttaaaat ttgattaaaa aatcaatttt gagatgaccc tttatttatt
    14341 ttttgtaata attgaaaaat aaacctgctt tcagtatatt ctttttaaga atctttgtat
    14401 taaatttata atacttagat atataatatc ttatatattt tattttaagt attaaaggtt
    14461 tgaatgtaac ttaaatatta aaagaggaac attgtaatat gtaacttgca taaaatatat
    14521 atactatagt gaaattattt tgattaaaat ttaaaatata aggtgtttta tgtgggggta
    14581 tatgtatatg aaaaattcta attttaatat attggcattt gatggtggtg gattaaaagg
    14641 ggcattgagt atatccatac ttgagaggat agtaaaagag tatccaaatc tattaaacaa
    14701 tataaatatg tttggaggta catctacagg gagtctaatt gcactagggc ttgcgtatgg
    14761 tgtaagccct aaagagataa aagaacttta ctcaattgaa aattcaaagt atatttttaa
    14821 taaaagttat gcagaaatac tcagaccaaa gtatgaaaac aaaaacttaa aagaagtttt
    14881 attaagtata tttccagagg aactagaatt aaaagattta aataaattag taatgatacc
    14941 aagtttttat ataggaaatg aggaaaatgc atggaaacca gtgttttata acaatatgcc
    15001 aaattctttt acaaagacta gcaaagttgt agatgtagca atggcaagta gtgctgctcc
    15061 ggtatttttt ccaacatata atcgtcatgt tgatggagga ataatagcaa ctgacccgag
    15121 tttagcgtgt ataattcatg ccattgacag tggatttaaa cttaagaata caagactttt
    15181 ttcaataggg actggatatg tatataacag tataaaggca gatactaccg aatggggagc
    15241 tattgactgg ataattaata aagaacccga tttaccaatt atatctatta ccttagaagg
    15301 aaattctcaa atgagtcagt tattttctca aaaacttctt ggagataatt actatagatt
    15361 aaatcctaag atggaaaaag atgtagctat ggatgattgt gatgcattag aatatctaat
    15421 gtctttagga gaaaattgtg atataaaaga tgcttttgga tggataaaga aaaagagctt
    15481 ttatagaaat tagattcaat ttgcaattgt atttttacac atgatttcat tgagtaggta
    15541 aaaataataa aatgcagatt attaagttac ttcttaggga ataaataaag tataatttat
    15601 ttaaggagtg atgaaaatga taaaacttgc tactttttca ggtggatgtt tttggtgtat
    15661 ggtaaaacct tttgataagt atgatggagt tattaaagta gtttctggat atacaggtgg
    15721 tcatgttgaa aaccctacat atcaagaggt atgctcagga actactggtc atttagaagc
    15781 aattcaaata acatatgatg atgatataat aagttatgat gaacttctaa atatcttctg
    15841 gaaacagatt aatcctacag atgatggtgg acaatttggt gataggggaa ctcaatataa
    15901 gactgctata ttttatcatg atgaagaaca aaaaaatata gctttagagt caagagaaca
    15961 tctggaaaat agtaaaatat ttgatagtaa aatagtgact gatataattc cagcaactaa
    16021 attctacgaa gcagaagaaa atcatcagga ttattataag aaaagaccat taaactacaa
    16081 tatgtattat aaagggtctg gaagatataa ttttgtaaaa agccattggg atggaaacaa
    16141 tataaatagg gaagagttaa aaaagactct aactcctata caatttgaag tcactcaaaa
    16201 tgatatgaca gaagtacctt ttgaaaatga atattatgac aataacaaag agggaattta
    16261 tgttgatatt gtaagtggag aagtgttatt ttcttcaaaa gataaatttg attctggatg
    16321 tgggtggcca agtttttcaa agccagttat agataaatct atcattgaga gaagtgattt
    16381 ctcacaaggt atgtacagag ttgaagtaag aagtgctaaa ggaaattctc atttaggtca
    16441 tgtatttgat gatggtccaa aagaacttgg aggtttaaga tattgtataa attctgcttc
    16501 tcttaaattt ataccaagag aaaatatgga agctttagga tatggagaat atttaaaact
    16561 ttttgagtaa ttaggaatat ttattataaa cttatctaaa aggtgaaaat ataaaaaaat
    16621 attttcacct tttgtttttt tgtcaataat atgataaatt attaattgta atcttattta
    16681 taccaataga ttaagaattt aattttgaaa gagagaaaac aaatgaattt aaaagacttt
    16741 aatggaaaga gattaaaatc agctagaatt tttagagcaa agacgataga acagttgtct
    16801 aaagaaacta aaataaataa aaaagattta aaagcttttg aggaaaataa gtatgtacca
    16861 aatatagaaa atacattaaa attatctaat atattaaatt ttccaaaaga gtatttttat
    16921 aaaaatgaaa atataaatat cgttgtagag gatagccact ttaaccctca atctaaacta
    16981 cctagagtag aagagatttc ttatagagaa aaaataatta taatacataa aatatattca
    17041 tttatggaga attatattaa gtttccaaaa gaaaacttgc caaatagaaa agtaatgtca
    17101 gatattaata taaatgatat agaatctctt gcatataaga ctagagagtt ttgggattta
    17161 aatagtactc caatagtaaa tatggtaagt ttgttagagt ctaaagggat tataatatca
    17221 ggtatgaatg tagatagaaa aggggcaact atctttactc aaaaacagag aattagtaaa
    17281 gaatctaaat atctaatatc tctgggtaat gacaaaaagt cagcatcaat tagaaattat
    17341 actttggcat gtgagcttgg atatataata tcaagtgaat taagaatacc aagtaagcaa
    17401 ttttcagaag atgagtatgc ctgtgcattt ttattgccaa aagagagttt tttaaaagat
    17461 ttgactcatc cagaagattt agattattat gtagaactaa agaaaaaatg gattgtacct
    17521 atatctgcta tgatttttag agcatataat ctagaaaaga taaattacaa aaaatacaat
    17581 tatcttatga atgaaatgga taaaaaaggc tggttgatag aagaaccact agacaaaatg
    17641 aaaggttcaa gcccaacgta tttaaaaaga gcagttgaat tattgataga aaataaaata
    17701 atgagtgtaa atagtatagt atcaagttta gaggaatttg gaataaatct ttatccagaa
    17761 gacttagaat tattgatggg attgaaaaaa ggattgttat ctcaagaggt aaataaaaaa
    17821 agtaaagtta taaaatttga tggtaaaaaa taggtttata ttttagtatt aaaattaaaa
    17881 gcaggtacaa atgatttaaa cattaactta gttaaaggtc ttttcaataa gtcatttacc
    17941 tgcttttagt gtaagaaaga atattgaatc taaagtgttt ttgaaagtgc aatatattcc
    18001 cttaaaacag aacaagattt attaaattca ttttgctcat attcagtcat attgatttca
    18061 ataatttctt caataccatc ttttcctata acacatggaa cacctgcaaa tacatttctt
    18121 tcgttatatt gaccttctag taatgtagaa actggaagaa cttttttctc attgtgtagt
    18181 atagctttta caatttctac taaagcagta cctataccaa attctgtaca atctttacca
    18241 tttattatac ttatccctgt ttttttattt ttttcaacta ttgatggtaa gtctaaattg
    18301 ctataagtac ttgggttgtc ttttatcatg tctaagattg gtttaccacc aattgaaaca
    18361 tgagaccaag gaaccatttg agaatctcca tgttcaccca tagaataagc ttgaattgat
    18421 tgttgagcga ttccagtttc ttcagataaa atccttctaa gtcttgttga atctaaagct
    18481 gttccagttc caatgacttt gtttttagga aagccagatt tttcccaaat ataatttgta
    18541 actacatcaa caggattaga tatgactaca aatataccat caaagccaga atcaactatg
    18601 ggttttacta tagattttat cattccaata gttggtctta gtaaatctaa tctagttgtg
    18661 ttttgtctac gtaaaggccc ttctgaagag tctgcaacac ttatcactac tatgtcagaa
    18721 tctttacagt cagaaaaagt tcctttttct atatgtactt tatgtggcag atatgaaact
    18781 gcatcagcta aatctaaagc ttgagctttt gatttagatt catctatatc aatcataaag
    18841 agttcatcac aaactccttg agttattaaa ctaaatccac aatgagaacc aacatgccct
    18901 gaacctacaa tagatatttt tcttggcttt attgccattt taaatcactc cccctaaaat
    18961 aacgatacat tgaaaattat agatgttatt aaaagctgtt tttggatatt ttaatattct
    19021 attatttcag aaaatttatt taatatgatt ttatactaaa atttttaaaa aagcaatgtt
    19081 aatatactct ctattagtga atattaaagt attatatgta tattaataat tattaaaata
    19141 tgtaatgtca ctgatagtta gaatatttaa gtgctaaaag atgtgtataa ataataatga
    19201 tgtcagttta taatgatatt aaattgagat atactgtttc tctaaattaa aaaataaagg
    19261 agtaaatgtg ttatgaatta tcatacaaaa gaagaattgg tggaagcact gagagtagta
    19321 tcttcaagta ttattaattg tggaaaagga cagaagaaat tttctgagga gacatctcat
    19381 catacacgtt ttaagaatat tatagaagta atgtatattt caaaatcatt aataatggat
    19441 gaaattagta aaagagattg aagcttattt tgcaatttaa catgttttaa tatacatttt
    19501 attatataag aaaataagta aacatacatg ttataaaata ttgaaataat atacaattat
    19561 aaatttgtta acattaatat ctatatgtta aaatatagta gaagatgtta gtaaataata
    19621 ggatgagttc tattttaata caattaaatt aagcttagtt tgaaatttgt atctaaaaag
    19681 taaagtaatc tagaattaag aaaatggaga tagaattata atggaaaaat tatattatac
    19741 aaatcagtat ataagagatt ttacagcaga aataattgaa ataaaagaag tagaaaataa
    19801 gtatcatgtt ttattagata agacagcttt ttttcctggt ggaggaggtc agtttggaga
    19861 cctgggaaaa atagagaatg atgatgtaat aaatgtgtat gaagatggaa aaaaaatata
    19921 ccatgtatta gataaaaaac ctataaagat acataaggta aagtgtagta ttgattggga
    19981 tagaagagaa gatggaatgc atcaacattt tggacaacat gtattgtctg gatgtttttt
    20041 taaaactttt aatgcaaata cgacaggttt tcatttggga aatgagtata gtacagtaga
    20101 tatagaaggt aatttagaag aggataaaat tagagagata gagttgtttg ccaatgaaat
    20161 tattcgtcaa aatatacaag tagagacatt acttccaacg aaaaaagaac taaaaaagat
    20221 ttggttaaga cgtgatttgc caaatactga tgaagagata agagtaataa aaataggtga
    20281 tttagatacg aatgcatgtt gtggagtgca tccaaaatca actggtgaat tgagaatgat
    20341 aaaaataaag aaatgggaaa aacataagtc aagtacaaga atagagtttc tagcaggtaa
    20401 aagggcagtg gatgaagtat tgaagaggga tatatatttg actaaaatat gtagatattt
    20461 aagctgtagt gaggaagatg ctataaatgg tattgtaaat ctaaatagta aagtggaaga
    20521 ggctttaatt aaaaaaagaa ggcttgaaga agtagtatct acatatcagg tcaaagaaat
    20581 gattgaaaaa gcaaataagg ttggcaatat ttcggtcatt aaaaaaattt atgatgatga
    20641 agatttgaaa tatgtaaata agatagcaaa taaaattgca gaatatgaaa atagtattgc
    20701 attattagct gttaaattta atgataaaat aaatttagtt tttgcatgtt ctaaaaattt
    20761 aaaagatatt aatatgggag ttttattaaa ggatgcaata aatcttatag atggcaaggg
    20821 tggtggaagt aaagtattag ctcaaggagg aggtaagaat aatggaaatt tagaggctac
    20881 acttgattat gcatttatga agatagaaaa aactctataa atatattata taaaaaacct
    20941 tagtagataa aatagatatg gaggaataag tatggagcaa caaaaggact acatagagtt
    21001 atatgaaaat gaagaactaa tagagataag agaagcacgt atggatgatt tggatacaat
    21061 agcaaaattt aattataatt tggctaaaga aactgaagga aaagaacttg atatggatgt
    21121 tttaactaaa ggtgtaaaag cattgttatt agatgagaga aaaggaaaat atcatgtata
    21181 tacagtattt gataaagttg ttgcacagat tatgtataca tatgagtgga gtgattggag
    21241 aaatggaaat ttcctttgga ttcagagtgt atatgtagat aaggaatata gaagaaaagg
    21301 tatctttaat tatttattta attatataaa aaatatatgt gataaagatg aaaatatagt
    21361 tggaatgaga ttatatgtag aaaaagaaaa cataaatgca aaagcaacat atgagtcttt
    21421 aaatatgtat gagtgtgatt ataatatgta tgaatacgaa gtagtacatt cgtaatataa
    21481 atttgtaata ctgttatact gatgttataa agtattgatt atattgacga ttatatgaaa
    21541 taaactggat attataatta gaatttttag ggggtataaa aatgggcgtt ttaaaaggaa
    21601 tgttttatgt atttttattt ttagatttag tgtcaatatt ctgtttcttt ttcaataaag
    21661 gaaaaatagc atctaataaa attgtgttta atgcaatagg agtacttaca tttgtacttt
    21721 gttttatgct ttttagttat tatcctaata ataatcttat tggaaaattt attgcttctc
    21781 tattttttat atttggagtt gcaggagtta tgttgaaaga aaaaaatttt ttatatgcta
    21841 gacttctttt aactgtagtt atagtttttt ctacattaag attgttcgtt attcaataaa
    21901 atgtatttgt ataaaaattt attaaagtct acacatttaa gtgtaggctt ttttgatttt
    21961 ttgtttgaaa attaaggaaa ttttaaggaa attttaaaat cgtcttaaat atttattgat
    22021 atacttaaaa tattaatagc gaaaggagac ttatcagtga tagaaagtaa aaagtcagaa
    22081 aaattgttac tgtcaattat atacataata tttttggtat atattttaat gattataaga
    22141 ataattttat ttagagatgt accaatttac gctattttca agggaacgtt taggaatgta
    22201 aatttaattc cattttatac aatatatcaa tttatagtag atagtaatct tgactttatg
    22261 aaagctactg taaatattat agaaaatata ggtatattta ttcctatggg aattttttta
    22321 cctatagtat gtaaaaatct aaataaaaaa actataatta tagtaattat acttgttagc
    22381 ctagcatttg aattaacaca atatattttt gctcttggaa gtagtgatat agatgatgtt
    22441 attttaaatt cattaggtgg cataattgga attaatattt acataaacat gaataaatta
    22501 tttcccaatg atattaacag atttaaggct ataataggta ctagtttagt tttaggagtt
    22561 ataggattag gagttatttc taaaaattat cataacttac taacttttaa atttagacct
    22621 gatagaaaaa tatcaaaaat attaattgaa gaaaataggg aaataattaa agatataaat
    22681 aaagatacag tagatatagt tgggacattt gagagcttta aaaaaggaat aataactatt
    22741 aaagcaggtt ctaataacaa agtaaagaga ccagagaatt taattgattc tgatggaaat
    22801 ataagaattt atttaaatga aaatacaaaa ttagtatctt atataattac caaagaatca
    22861 aaaatggata tagttaaata tgaggaattt gatgtgaaga atttagattt attaaggaga
    22921 tatgatacta ttaatgtttg gattgataaa gaaaatcagc caaaggataa acatggtatt
    22981 atggctagta aattattaat tggattgtat gaataaaata ttaaacaaga ataaaagaat
    23041 aacaaatata aaaaacgaaa aaactatttc tataattatt tttacgttgt gcataaaata
    23101 agaacattag tgaaggagta gagataaatt atggagataa taaaatatat cttgtacttt
    23161 tttatatatt catttttagg atggacagta gaaagtatag gatgttctat agcaagcaaa
    23221 agaataatca acagaggttt tttaaatggt ccaatatgtc ctgtttatgg ttttggagcg
    23281 gtaattgtga tatcactatt gggaagattt aataatgtag taatagtatt tctattagga
    23341 atgattttaa ctacgatact agaatatttt acaggattta ttttagaaac cttatttcat
    23401 gctaaatggt gggattattc tgacagaaaa ttcaatataa agggtagagt atgtttaaaa
    23461 aatgcaatat actttggtgt aatgtctgtt ttaataataa gatttataca tccatttata
    23521 aaatattttg taagtataat tccatataga atattaattt caatggctat aattacaaca
    23581 ctttggacta tacttgattt gattgttact attataacac ttaaaaaatt agatataaag
    23641 ttaaacttac tagacgatat aattacagac cttaatgata taaatgtgaa attggataaa
    23701 tttgatagag gagaaataca agctttattt aaaacaataa ataacgacga attagaagtt
    23761 agagaaaaaa taaacaaaat aaatagtaag ttggaccgta tagagtctaa tattatttta
    23821 caaaaaagag ttataaaagc ttttccacat ataaaacata aaaaacaaca agagcaacta
    23881 gaacatttta aaaaaattat taatgagaaa aggtaattat acaatttaat gaagacgaat
    23941 agaataatgg tatttataag atgattttca gaggactcta taaaaataga atagagtcct
    24001 ttattttttg aaaaataatg tttatttgat aaaaataaaa tatattgttt ctgaataaca
    24061 aatattttga aaattataaa aacatatatt gacaatttgt gtcaaaaata ctaacattaa
    24121 gtatataaag aattttatat gagaatatct ttataaatcg caataatttt aaaacataaa
    24181 tttatttaaa gaggggatga tttgccaatg agcgagataa ctagtcaaat gataagtaca
    24241 gaagaaaaaa aatatgttgc taaaactcaa aagatacctt attatccagt agcatttaaa
    24301 tcaggtgatg gtgcaatgct atatgattat gaaggtaatg aatatgtaga ttttttagca
    24361 agtgcaggct ctgcaaatgt aggtcatggt aataaggaaa tctcacaagc agttaaagaa
    24421 caaatggatg atataacaca atatacactt gcatatttcc atagtgatcc tcctgtaaaa
    24481 ttagctgaga agcttgtgga aatagcccct ggagataatg ataaaaaagt actatacagt
    24541 gcaactggtt ctgcttgtat agatgctgct ataaaattag caagaggata tactggaaga
    24601 acaaagataa tatctatgtg tgaatcttat catggaagta cttatggagc tatatctata
    24661 tctgctttaa gtacaaatat gagaagaaaa atgggtccat tgttaccaga agtttatcac
    24721 ttccattatc ctgataaaaa tagaacagct aaagaatgtt tagatgagat agaatatgct
    24781 tttgcacact atctaccagc agaagaggta gctgcaatat ttatagagcc aattgcagga
    24841 gatgcaggaa taatagtgcc tccagtagag tgggtacaag gtttaagtaa aatatgtaaa
    24901 gaaaatggaa tattacttgt aagtgatgaa atacaacaag gtatgggaag aacaggtaag
    24961 tggtttggta tagaaaattt tggtgttgaa gcagacctta tagttcttgg aaaatctgtt
    25021 ggaggtggat tacctctagg agcagttgtt ggaagaacag aaataatgca aagtcttgat
    25081 gcaccagcac atttatttac tttagctgga aacacaacag tatgtgtggc tgctttaaaa
    25141 tctatagaga taattgaaaa agaaaactta cttcaaaaga gtatagaaat gggagattat
    25201 attaaagcag gatttgaaaa actaaaagaa aaatacgata taattggaga aataagaggc
    25261 ataggattat ctataggagt tgatatagtt aaaggaaaag gttctaatga aaaacatcca
    25321 gatgctacag ctaagatatg ttatagatgt atacaaactg gattaataat gatattctta
    25381 ggacaatcta ctttaagagt gcaaccacct ctagtaataa ctaaggagca agtagataaa
    25441 gcaatgaaca tcatagattc tgcaatagat gattatttaa atggtagaat tggtgatgaa
    25501 gtatatgaag taactcaagg ttggtaaaat aaatattaaa tgaaaatagg agttatctca
    25561 attttagaaa attatttctg aaatgagata actcttttaa gttacccaca aataagaaaa
    25621 ttgtttgatt cattaaagac tatatttcgg atgtcgtttt tgtgagtatc agagacagta
    25681 ttacgagaat aattaccttt attcgtacta tctgttaatt tagttataat taagatagct
    25741 aaaagaataa gaattactgt gtataaagca ataacatatg gttttctttt atatttgtat
    25801 ttgttattga aaaaagaatg gccataatta tttttattta ctttagatgt atttgtattc
    25861 tttttcttgt tacctttctt tttatcatcc ttttttctat ttttagggta aggaatgact
    25921 ttgtgtgtat tatcaagttt gatattttta tttttttgaa tattgttttc caggctagcc
    25981 tttttttctc caaattgaat agttttattg gtattgttgt tatctttcaa tgttaatctc
    26041 cctcccttaa actttccctt tagataatat tactactaac ctatggaata tacaataaat
    26101 aatatataag taataaaatt ttataggtat aaatctcttt ctccacgctc taaggcagtc
    26161 atattgttag atactatgtt tcttatatct tctctttcta tcttacctat ttcttctgcg
    26221 ataagttttt tacccataat tttaagttct tcatctccat aatcgattaa aaattcattt
    26281 aatgtagtaa gagcatttgg tgtacataca ttatggattt gtcgactttt agctaagctc
    26341 atgaatctat cgccagttct acctttacga taacaagctg tacaataact aggtatatat
    26401 ccatcagtaa tcagttcttt aagcacctca acagggcttc tatggtctcc aacttcaaat
    26461 tgttctgtat tgtcaccatc ttcatatgct ttatatcctc caacacctgt tagagaacct
    26521 gcactaattt gtgatacacc atattttagt aactcatttc tcatttcagc agtttctcta
    26581 gtggacatta tgattccagt aaaaggaaca gccaatctag ttatagctac tatttttttg
    26641 aacatatcgt cagaaactaa gtgaggaaaa tcttctaagc tcataccttc agcttttttc
    26701 aatctaggga aagatatagt atggaaacct acaccaaatt tttcctctaa gtgttcgttg
    26761 tgcatcataa gtcctagaac ttcaaattta gggtcagata aaccaaataa aactcctgca
    26821 ccaacatcat caacaccagc ttccatagct ctatcaaaag ctgttaaatg gtaataatag
    26881 tcatttttta tagattgacc atgcattttt ataaatgttg gtttgtgata agtttcttgg
    26941 aataatatat aagttcctat tcctttttct tttagtaatt tatactcatc tacacttgta
    27001 gctgctatgt taacgtttac ccttcttata tttccgtttt cattatatgt tgaataaatt
    27061 gcatctaagc aatctaagat gtaatttata tcacaatttt tagggtcttc accagcttct
    27121 agagcaagtc ttttatgacc cattttttct aatattttaa cctcttcctt tatctcttcc
    27181 atggtaagtt tttttctttt aaatttgttg catttactaa aaccgcaata aacacattca
    27241 tttacacagt agtttgatac ataaagaggg gcaaataaaa ccactctatt accatatatt
    27301 tcatttttta tttgcccagc tatactaaat aatctatcta gttgtttttt atcttctact
    27361 tcaagaagtg tagctatatc tttataacta agtttttccc ttctatcagc cttatcaagt
    27421 accttttcaa tatcatcaga agttgaattt tttgcatctt ctaataaaga attaataagt
    27481 tcatggttta tgaacattta caaacgcctc cattcaatat tatcaccgcg agaatagtca
    27541 acttcaagtc ctaatgactt gatgttttct tctaaacttt ggtgatattc acaagcttct
    27601 tgaccagtaa aggctttgtt atcgtaaaga gaatattgtt ttctaaattc ttgaggagaa
    27661 aggtttggca taattacatt gcaaccagct aaaagacctg catttctacc actagggttt
    27721 atagatgcca aggctgttgt agcgggtaat aaaacttttg gaagtagaag tcttgtaatt
    27781 gaaagcataa gtaatgtctt ctctaaatct ccatgtttat aatccttaaa aattgtatca
    27841 tggtgtggaa taaaaggtcc tattccaacc atatgaggat ttaactcttt taggtataat
    27901 aaatcacgaa caaggtcttc gttgttctga aatggtgatt caaccataaa tccagcacct
    27961 acctgataac caatttcttt aaggtttttt aggcattctt ttctagttct aagctcaatg
    28021 tttggcggat gtaatttttt ataatgactg tctgtagcag tttcatgtct taaaagatat
    28081 ctatctgcac cacataaaaa gtatttttta tacgaatcat aactcttttc tcctagtgat
    28141 agagttatgg cacaatcctc atatttattt tttatacttg aaacaatttc acatatttta
    28201 tcatcagtaa aatatgcatc ttcaccacct tgcaaaacga atgttctgta tcctatttta
    28261 taacctatat cacaacattc aagtatttca tcaagtgaaa gcctgtatct tatgatattt
    28321 ttattagaag attgtattcc acaatagtag caattatttt tacaatagtt tgtaagctct
    28381 ataagtcctc tcaagtagac tctatttcca taatgtttat ttctcatgtc gctagcttgt
    28441 ttataaagat agtttcttaa attttgttcg aagttatatt cctcattgtc gatattttct
    28501 attaaatata gtagttcatc aaaacttaat gaattaatgc tgtaaagttt atctataaag
    28561 tatttaatct tatttttagt catattcaaa tatgtaatta ttaagtatag ttaaattttt
    28621 aataattgaa aagttcaagt gatctttcca aaataccttt tacatatgct attaagacac
    28681 catagtttac aataggtaca ttgaaagatt ttgccttttc tattctagat aacattccag
    28741 ctctattcat catacaagct ccacagtgaa ctacaagggc atatttattt atatcttcag
    28801 tgaaggatac tccagaacta aattcaaaag taatgttttt gccagttttc tttctaatca
    28861 tattaggaat ttttactgtt ccaatatcat cagtttgtct atgatgggta catccttcgg
    28921 ccatcaagat tttatcacca tcttttaaat tttctaaagc ataagctcca ttaatcaatt
    28981 ctttaaggtc tcccttttgt ctagcaaaca atatagaaaa agatgtaaga ggaatatctt
    29041 tttgtgtatc tttatctact tgtggaaata cttgagagtc agtaataaca agttttggtt
    29101 ttttgcctaa attagataga gtttctttta aactatcttc ttttgtaact atagaaattg
    29161 caccattatc caaaatatct cttataactt gctgttgagg aagtataagt ctaccttttg
    29221 gagctgcttt atctattgga acaactaaaa caactaaatc atttggttca attaaatctg
    29281 ataccaattt gaactcagtg ctatccttag gcaaaacttt tattatttca ttttttaaat
    29341 tttcaattcc aattttatct gttgatgaga cagaaacaac tggacattta actttatttt
    29401 tagttaagtt taaaatttct gattgattct taatagtatc aattttgtta agaattagaa
    29461 tatgagggat attcttatca ttaaattttt caattagtga caaatcttct tgtgatatac
    29521 caatttggca atccactact agtaaagcta tatctgtctt ttctaaaaca tctagtgatt
    29581 tacctattct aagttcacca agttcaccaa catcatcaag accagcagta tctataagaa
    29641 cacaaggtcc tataggaagg atttccattg gtctaaatac tgggtctgta gtagttccag
    29701 caatatctga gactattgca gcactttgat ttgttatagc atttattatg ctagatttac
    29761 ctgcatttct tttaccaaag agacctatat gtactcttac cgattgtgga gtagaattta
    29821 gactcatttg tactcaccac cttaaacttc tttttttgat atactagttt ttacagatac
    29881 atgaggtatg ttgcccaatt taccagtcaa actattaata gtgtccattt cgccaacaac
    29941 tgctatacat acgattgaga caccttcttc ttcgcaagga atgcccattc ttcctttaat
    30001 aataccttta aaacctgata caacctcatt gaatttaaat tgacattctt ttggttcttc
    30061 caaaatagca cttataactg caaccttttt cataaatatc ctcctaactc agaaaatatg
    30121 tcttaaacaa atccaaaatc aaaaaacttt tctttgtaaa gaaaagtttc tacaaaagaa
    30181 aagttattaa ttacacaagt ataatgtgct atattaaact atttccttac agattagata
    30241 actcttttct ggtagggtta gcttgtaaaa atttaattta acaacaagta actgaagaaa
    30301 atttttatac aatttatata aattataata aaaattaact aaagaaaatt gaagttactt
    30361 atataatagt agtaaattga aattaagtct atagaaaaac caatttttgt ataaaaataa
    30421 aaattaaagt taattatttg ttaagaattg actttggtaa aatatataat taattattct
    30481 ttaagcatat aatttataag taattttagt gtattttcaa tagcttctat atgtgttctt
    30541 tcataatggt gactattgtt tgttccagga ccaacacatg ctatttgaac atcttctccc
    30601 caacgaatag cttctgaagc atctgaacca tagaaagtaa atacatcgac agcgtagtct
    30661 aaattattgt cttctgcaac atcgacaagc ttgtttctta aattaaaatc atataatgat
    30721 aaattatctt ttgcaactat agttacacca tgttcactag atgtttgact tggtccagta
    30781 ggtgctatat ctattgctac aaattctttt gttttttcag gtaaacattt agaaacacca
    30841 tgtccaattt cttcataatt acttatataa aagttagtag tatgcttagg tgttaaattg
    30901 ttttctttaa aatatctaca tatttcaaga accattgcta cagctgattt attatctata
    30961 tatctagatt ttataaaacc agattctgta gcctcaaatc tatggtctag gcatacaaaa
    31021 tccccaacac ttattcctaa atctaataca tcttgctttg taaatacttt ttcatcaagt
    31081 ctaataatca ttgtttcttc atttctttca gtggcagctt ttgtttgacc atatatatga
    31141 gtagaagcat acttaaatac aacacttcct ctgatttttt taccttttct agttataaca
    31201 gtacagtttt ctccctctat agccgcccaa catccaccac caactttatg gtatttaaga
    31261 gtaccatcag atgatatttc ttttactata gctccaagtg tatccatatg tgcagatatt
    31321 gttatttgat ttgaatcatc ttcaccagga agagtagcta taagtgcacc tttttttgta
    31381 agaatagtgt caagacttaa attttcaaaa tcttttttga tttctaaaac tgcattttca
    31441 gtatatccag ctgggcttgg aatgtccaaa tattttttca ttaaatttat agtattagtt
    31501 aaatttaaat tcatattgtt tcctcctaaa taaatatatt tatacaaatt
//
LOCUS       DAEHWO010000045        31005 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEHWO010000045 DAEHWO010000000
VERSION     DAEHWO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31005
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.045"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            27..101
                     /locus_tag="KNP54_002376"
     tRNA            27..101
                     /locus_tag="KNP54_002376"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KNP54_002377"
     tRNA            116..200
                     /locus_tag="KNP54_002377"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KNP54_002378"
     tRNA            210..293
                     /locus_tag="KNP54_002378"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="KNP54_002379"
     tRNA            317..391
                     /locus_tag="KNP54_002379"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="KNP54_002380"
     tRNA            416..492
                     /locus_tag="KNP54_002380"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="KNP54_002381"
     tRNA            502..577
                     /locus_tag="KNP54_002381"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="KNP54_002382"
     tRNA            586..661
                     /locus_tag="KNP54_002382"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="KNP54_002383"
     tRNA            664..752
                     /locus_tag="KNP54_002383"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="KNP54_002384"
     tRNA            756..831
                     /locus_tag="KNP54_002384"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="KNP54_002385"
     tRNA            838..911
                     /locus_tag="KNP54_002385"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="KNP54_002386"
     tRNA            926..1002
                     /locus_tag="KNP54_002386"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="KNP54_002387"
     tRNA            1020..1096
                     /locus_tag="KNP54_002387"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="KNP54_002388"
     tRNA            1105..1180
                     /locus_tag="KNP54_002388"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="KNP54_002389"
     tRNA            1188..1261
                     /locus_tag="KNP54_002389"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="KNP54_002390"
     tRNA            1269..1345
                     /locus_tag="KNP54_002390"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="KNP54_002391"
     tRNA            1358..1433
                     /locus_tag="KNP54_002391"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="KNP54_002392"
     CDS             1509..1922
                     /locus_tag="KNP54_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893273.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="KNP54_002393"
     CDS             2231..5662
                     /locus_tag="KNP54_002393"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBF0893274.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTRESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="KNP54_002394"
     CDS             5904..7832
                     /locus_tag="KNP54_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBF0893275.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="KNP54_002395"
     CDS             8285..8749
                     /locus_tag="KNP54_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBF0893276.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="KNP54_002396"
     CDS             8756..9250
                     /locus_tag="KNP54_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBF0893277.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="KNP54_002397"
     CDS             9266..10291
                     /locus_tag="KNP54_002397"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBF0893278.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="KNP54_002398"
     CDS             10278..12725
                     /locus_tag="KNP54_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBF0893279.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNKVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="KNP54_002399"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="KNP54_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBF0893280.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSEKLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="KNP54_002400"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="KNP54_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBF0893281.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="KNP54_002401"
     CDS             15440..16534
                     /locus_tag="KNP54_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBF0893282.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="KNP54_002402"
     CDS             16663..18840
                     /locus_tag="KNP54_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893283.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19020..19871)
                     /locus_tag="KNP54_002403"
     CDS             complement(19020..19871)
                     /locus_tag="KNP54_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0893284.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKNLPKI"
     gene            20088..21254
                     /locus_tag="KNP54_002404"
     CDS             20088..21254
                     /locus_tag="KNP54_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBF0893285.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFAMIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLVKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="KNP54_002405"
     CDS             21276..22922
                     /locus_tag="KNP54_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBF0893286.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYVQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            23019..24392
                     /locus_tag="KNP54_002406"
     CDS             23019..24392
                     /locus_tag="KNP54_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0893287.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            24837..25790
                     /locus_tag="KNP54_002407"
     CDS             24837..25790
                     /locus_tag="KNP54_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBF0893288.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="KNP54_002408"
     CDS             25828..26790
                     /locus_tag="KNP54_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBF0893289.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="KNP54_002409"
     CDS             26815..27801
                     /locus_tag="KNP54_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBF0893290.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="KNP54_002410"
     CDS             27814..28860
                     /locus_tag="KNP54_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBF0893291.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="KNP54_002411"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="KNP54_002411"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBF0893292.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
BASE COUNT        12463 a         3406 c         5941 g         9195 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actgaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taaaaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagataa aaatagtgaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttagccagt ctatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttgaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctata aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcggatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggcggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagagcttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttca ttagatgata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcattatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccatta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcaga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaagagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag atataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacattag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcact
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag acaatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cggtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacagaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaaa attactgagg gtgtactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gctgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtt
     7381 taaaagactc tatgcaaaaa ggtatattag caggatatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aaaatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcacaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaata
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatatc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atgggcatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaagaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgagttag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agtataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcgttgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgtcggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaaggagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagagaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gagctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttagca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaataaag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatcttattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgcggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gagagtaaag aagaagagcg gtttacaaca gatataaatg aattagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaaattat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtatttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgagg ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aagatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagagccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattaga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatatcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgataa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagactaaag aagcttacaa aaataatgat
    17341 gtgatttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtat gaaagataac atagaaaaaa atatagatat atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actgtctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tcgccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaacgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgat tgtataattg gagctagata ttatggagta
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa atggtctata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgta aagatagatt tcaaaaaaat cgtattatta
    18421 ggtatagcag tagtatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggcatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc ttacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatattaat acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttatctc aaaattgatt
    18961 attctaatca aattttaaga taaactcttt tttattataa agataaataa catataactt
    19021 catattttag gtagattttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtat taattaagtc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ttgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agttagtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga actaagttta atttctctca tgttttctaa tataagttta
    19501 actttacttg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatttt gataaataca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagattaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca atgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgaggcatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatataag gtaatgcgtc cttatatgag ggaggaaaac gttatagtat
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atgttgttct agatacacac caatatttga tgttagctga agcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattaggg aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gcttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc tagtcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccctgt ttgacttatt gtgaagaaga agatttattt tatatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatct acactcatca ggttttgatg
    21661 cgtctatttt tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacaa
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggggacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 aattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggac aagaatcaag aacatcatta aataaagtga
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaaaacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatgta caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca gagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagtaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtgg taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa tcatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgtcttttta taagcttgat aaagaatata
    24361 gtactatact taatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gttttttaga agtgatttaa taagttattg ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcactaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aagcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaggatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagcc gtaagtttag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggagc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gcttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg cccaggaggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ctatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag cactgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatataatgg aaagataaga aagtgtgatg tggaaaaatt aactgcaaaa
    28081 gaaactattg tatcgactaa tacatctaaa tctagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagcatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat tttgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata taagaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa
    29341 tcaaaatata gaatttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaagaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagagc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtgaa
    30541 ggtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcatta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgcataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga aaagtgattt ttttg
//
LOCUS       DAEHWO010000046        30956 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEHWO010000046 DAEHWO010000000
VERSION     DAEHWO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30956
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.046"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            155..1081
                     /locus_tag="KNP54_002412"
     CDS             155..1081
                     /locus_tag="KNP54_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBF0893293.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(1270..1890)
                     /locus_tag="KNP54_002413"
     CDS             complement(1270..1890)
                     /locus_tag="KNP54_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893294.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYKEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGVTCFPSENTEVIIEDLTTMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(1862..3445)
                     /locus_tag="KNP54_002414"
     CDS             complement(1862..3445)
                     /locus_tag="KNP54_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0893295.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNISDNGVANTSFKTPLDITKITFDTIKHKGIISIKEQVENLGGTISVSDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            complement(3589..5616)
                     /locus_tag="KNP54_002415"
     CDS             complement(3589..5616)
                     /locus_tag="KNP54_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893296.1"
                     /translation="MNIFYTAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAVSNGKFFYKTPLVKLIRYEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQNSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTRILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYTNIQIKKIIKKQVLPFFNIPFLLGIVDCIFAT
                     LVYKTALMQNLLGNSLSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKK"
     gene            complement(5629..6378)
                     /locus_tag="KNP54_002416"
     CDS             complement(5629..6378)
                     /locus_tag="KNP54_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893297.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYVASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            complement(6677..8329)
                     /locus_tag="KNP54_002417"
     CDS             complement(6677..8329)
                     /locus_tag="KNP54_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBF0893298.1"
                     /translation="MNKKNLAILISGIMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            8917..10038
                     /locus_tag="KNP54_002418"
     CDS             8917..10038
                     /locus_tag="KNP54_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBF0893299.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            10074..10487
                     /locus_tag="KNP54_002419"
     CDS             10074..10487
                     /locus_tag="KNP54_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0893300.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            10480..11019
                     /locus_tag="KNP54_002420"
     CDS             10480..11019
                     /locus_tag="KNP54_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0893301.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(11219..11704)
                     /locus_tag="KNP54_002421"
     CDS             complement(11219..11704)
                     /locus_tag="KNP54_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893302.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            12609..12986
                     /locus_tag="KNP54_002422"
     CDS             12609..12986
                     /locus_tag="KNP54_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBF0893303.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            13382..15187
                     /locus_tag="KNP54_002423"
     CDS             13382..15187
                     /locus_tag="KNP54_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893304.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            15264..15803
                     /locus_tag="KNP54_002424"
                     /pseudo
     CDS             15264..15803
                     /locus_tag="KNP54_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            16426..17640
                     /gene="dpaL"
                     /locus_tag="KNP54_002425"
     CDS             16426..17640
                     /gene="dpaL"
                     /locus_tag="KNP54_002425"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBF0893305.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            17970..19157
                     /locus_tag="KNP54_002426"
     CDS             17970..19157
                     /locus_tag="KNP54_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBF0893306.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            19173..20756
                     /locus_tag="KNP54_002427"
     CDS             19173..20756
                     /locus_tag="KNP54_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBF0893307.1"
                     /translation="MRILIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKNLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            20784..22112
                     /gene="ssnA"
                     /locus_tag="KNP54_002428"
     CDS             20784..22112
                     /gene="ssnA"
                     /locus_tag="KNP54_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBF0893308.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            22311..23663
                     /locus_tag="KNP54_002429"
     CDS             22311..23663
                     /locus_tag="KNP54_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBF0893309.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            23855..24964
                     /locus_tag="KNP54_002430"
     CDS             23855..24964
                     /locus_tag="KNP54_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0893310.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            25247..26638
                     /gene="hydA"
                     /locus_tag="KNP54_002431"
     CDS             25247..26638
                     /gene="hydA"
                     /locus_tag="KNP54_002431"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBF0893311.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            26632..29193
                     /gene="xdh"
                     /locus_tag="KNP54_002432"
     CDS             26632..29193
                     /gene="xdh"
                     /locus_tag="KNP54_002432"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBF0893312.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSIPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            29345..30691
                     /gene="rpoN"
                     /locus_tag="KNP54_002433"
     CDS             29345..30691
                     /gene="rpoN"
                     /locus_tag="KNP54_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBF0893313.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT        11965 a         3683 c         5439 g         9869 t
ORIGIN      
        1 aaaagttaaa tctacactat taacttatta tacttaaaac tttaaaatga aaatatcaaa
       61 gaatactttt taataaaaat aatcatttaa taagttattt aaaaatctaa aaactttaca
      121 acaaattatc tatttaaatt ggaggagtgg gaatatgagt aatagttttt atcaattaaa
      181 ttcagcagta ttatatttta atgaaaaaag agatgtaaat agaataaggt ttaatcacta
      241 tgtaatgaga aaagaaaata tacaaagatt aaaaggaact ctgccaagag gacaatttat
      301 gatgacagta aggaaagctg catctgacct tgatgtatct atatctacaa taagtagact
      361 tgtaaatgaa tttatagatt taggtatatt gagattaata agtaggggag taaagggaaa
      421 ttgttgttct gtatatagtt atgtttgttc tgaaagtagt aatgcagaaa ttgtaacaaa
      481 gaatggtgat attttcaaaa atatagagaa atacattgat gcaactatta acaataacca
      541 aaaaacaatg aaatataaac atagaaatga gttgtttaag aacagtaata ccaacatata
      601 cagccgtata aatcaagaga gtatagacaa agattatgat ttgataattc atactgggta
      661 tgaaacagaa aatgagacaa agaaaaaaga attattaaaa aataatttaa ataaaaagaa
      721 tttaaataaa aatacctttg aaaattcgga tgaagatttg actgaagatt ctacttacaa
      781 aaatccagaa agcatacatg aaattattat aagaaaatta aatagtgaat caggaaaaaa
      841 ttttaaagct gatttgagta taactaaggc acttatagat aaaagattaa aagaagggta
      901 tagtttagaa gatttttaca aggttataga ggcaaaggta agaagatgga gatatacaga
      961 tatggaaata tatatagaac caacaattct gtttgggtat gaatttgagt cgtatttaaa
     1021 tgaggagagt tctttatctg cttgtaatta tggtgatatg tgttatgaag atatgtattg
     1081 agatattagt tgctttttag ttgtttaaaa tatgtttata tataaatata aatagtgtat
     1141 taaaatggag ttgtctcaaa atagagagaa gcctcttctt aattgtttaa atgatgaaaa
     1201 tatatttgat ttaatacaaa ggagagtgct ttatgagtta gaagatttat tttgagacac
     1261 tcactttttt taatatactg gagaaatata acccatttta atagcttttg taatagcctc
     1321 aactgatgat gaaacatcta gcttgtcata tatgtgttgt aaatgatttg ataatgttct
     1381 ttcacttata tacaattcat cagcaattat ttttcttttt ttaccactac agataagctg
     1441 taaaattctt ttctccatag tagttaaatc ttcaataatt acttcagtat tttcagatgg
     1501 aaaacaagtt accccttgat agacttttaa taatgaatca attaaactat cagggctaat
     1561 attcttattg aggaatccat agatacctat ttttttagcc tcatgtttat aaactgggag
     1621 gtcgtatcca gtcaagatta ttattttaat agttgaatta gtctctaata aattataagc
     1681 tacttttaag ccatcacatt cacttaagcc tctaaggttt atatccatta agacaatgtc
     1741 tattttttta tcttgaatca tttctgaaag attatggatg tcctgtgtgg aataaaactg
     1801 ttcgatttct ttgtattctt ctagtgcaat tgacaagctt ttagcaaaaa gcatatggtc
     1861 atcaactaac aaaatattta taagaaccat ctcctttcat agggattgta atctgtacac
     1921 aaactccatg aggtatatta tcagaaacac ttatcgttcc tcctagattt tctacttgtt
     1981 ctttaattga tataatccct ttgtgtttta ttgtatcaaa agtaatttta gttatatcta
     2041 aaggcgtttt aaaagatgta tttgccacac cattatcact aatatttaat tttattatat
     2101 ttttttctag tgctaaagct atccatgcat ggctaccatt tgaatgttta tacacatttg
     2161 tcaataattc tttaatcagt cgatatatca atatatcata tggttcaact aagaataaag
     2221 tatcagaaca cttaaatgaa acacaaatat ttttttgtgg aaaggatgaa gaaacacttt
     2281 caattaaatt ctgataattt tcttttactg ttaaattttt taaaataaca ggatgatagt
     2341 cttgcatttg cttccttata catgtattta gattgttaag tgtttcatat ataatatctt
     2401 gaacatctgg gcgatatgac ttactcatca tgttttttat tgaaagcagg ttctgtaata
     2461 tgtcatcatg taaaaaatta gaaaactctg tttttagttg ttcttcttgt tgtaattttt
     2521 ctaatgcaaa agtatacttg ctatttttaa ctactttatt tttttcatct ctaaggttaa
     2581 actccaaaat aatgttacag aggaaaatga gcataaataa aacatttata gctattaata
     2641 ttatagaaaa attcccattg gcaaatagta cgaccaagct aattactaaa atacttataa
     2701 aaagaaatat agccctttgt tttatgttaa aaactgttga aataggaaaa ctatcatttt
     2761 ctttaagtgc aataccatga atactcataa aaaataccag tacagttaga tagattccaa
     2821 aattaccaat atgatttgat attcttagtg taaaaaaata ataagtaagg aatcctataa
     2881 ttgttataaa tactgaaatc gatataggtt ttttttcgct ttttatgaca aaaacaaccc
     2941 ttttcaaatg ataaaaaata atatagaaaa agcttattat actaacaaca aactgtattc
     3001 cgtacataca agcatacgtt ctgttagaaa taaatgctcc tacaattgca ccaatgcagg
     3061 tgataagcaa taaaatgtct gttatcttac ggaaattgta tccactacct tgaaacaaaa
     3121 ataaaaatat aaatttaata gagacataca ctataactgt gcttaatatt ttaaaaataa
     3181 tagtgcctat tggtgtggtt acaaatgata agagtaaata ccaactgtct agtgctagta
     3241 atccacaaaa caatgaaata atgttatttt ctcggacatt acaagaggtt atatatgtga
     3301 tgtctatgag taataatgtt gaaattatta agggaataat gctttgaata ttcatataag
     3361 tttcagtgct tgtagatatt cccatgaaga gaagtgatag aatgtagttt cctaaaaata
     3421 gtatttttaa attaaaattt gtcaatctta tacacctcct tatgagttaa ttatattaat
     3481 tttatgacta aatcaaactt aagaatttat agttttaaat tatatcaaat acttataaat
     3541 gaagtatacc aaatcgtcac acctttaagc ttgacgattt ggcaaatatt atttttttaa
     3601 tacaatttta caacaggatt taatagtaag tatgtaatat atcaaatata ctacagaagt
     3661 taagaaaatt gcaataatca caggtatgta ttgtgaaagt gaatttccaa gtaaattctg
     3721 catcaaagca gtcttataaa ccaaggtagc aaatatacag tccactatac caagtaaaaa
     3781 cggaatatta aaaaatggca atacttgttt tttaataatt tttttaattt gtatattagt
     3841 ataacccatt ttctgtaaaa ttttataatc agatgttgaa tctgaaattg ctgatatatt
     3901 gttaaagtat aaaatacttc caacagcaat aaagaataat accacaagaa atccgattaa
     3961 cagaaatgta gaactattaa ttgataataa atcatttatc ctgtgagaat atccttgtaa
     4021 ataagggctt ccatctaaat aatctgaaat attactatat aaattttcat tatttttaat
     4081 tgatttacca ttaatactta aaattcttgt cattggtaat ttattttgtg ctatttgctc
     4141 atatatacta tcattaacga taagtgttcc aacgctattg gcaaaagaaa tagcattgtt
     4201 taatgatgtt tcccttacag ctacaggtgt ttctttacca ttaacaagta atggataaat
     4261 cgttccattt tcactatatc catcattatt tggttgatat ttcattaaaa tacattcatt
     4321 atcccttaaa ggggtaagtt gttttagtag ctttgttcga ttttgtgcct ttaataaagt
     4381 ataataatca gaaaaagata tacattcaaa tcctgattct cttgaaataa cttctttaga
     4441 agaactacta ttggataaat tattcttaga tgtaccaatt tcatattcaa atggaaggtc
     4501 ttttgatgaa gattttacct tataaatatt tgtctgtgta aaaataatat catctgtatt
     4561 agacgtatat tgactgacaa tttgttttac atcttctatt tgtttatttt tttctactct
     4621 aaattctatc tctgaaggtg caatacgcga aacagatgca atagggtagt ataaggacag
     4681 tgccataaca cttgaaactg tcaaagtagt agcagagagt aatgtaagca taattagagt
     4741 tttagagttt gaacgtatac gatagataaa gtttggaata gctattatct tcatatctgt
     4801 gtagaaagta cgtttatttt ttttactatt ttgcataata tatggaagaa aggaattgat
     4861 aaagagaact gtaccaatta caatgataat catagttatc aagcccattt gataaaatcc
     4921 aatacttacc catactgatt tagctccacg aagaatatct agtgataaac aatacccgct
     4981 taaaatcata ataaacccca taaaggctgg aatttttctg aactttaatt ttttttctgc
     5041 acttttttca tatcttatca attttacaag tggagtctta taaaaaaatt taccatttga
     5101 tacagctaag actaaaacaa ctaatgctat aaagataatt gttttattta ttgcatttat
     5161 attaaaaaat ggtatctgtg aattatcaat tgataaatta agtagtgctg taattccaaa
     5221 gacaataccc ttatgtgcca atgctcctaa taccaatcca ataataaaag ctccactaca
     5281 aattaataca ttttcaaagg taagtagcga taatattgta aacttacgat agccaagtaa
     5341 agcatatata cctaattctt ttgtacgacg tctcaagaag aatcgatttg agtatgccat
     5401 atagaagatg acaaatgcca tcaaaaatat cgaaataaca ttacacatag attcaactct
     5461 accatcagtt gaaatttttt ctagcattat cttattaaca gaaaatgaag taaatgcgaa
     5521 aaatacagta ataacaaaag agactgaaag tagatataga gaatagaatg aaaagttttt
     5581 tttaagattc tttattgccg tataaaaaat gttcattaaa ttatcctcct atcttttagt
     5641 atccaatttt gcaatttctt gaataatcaa ctcataaaat gtatgtctat tattctgttg
     5701 tttatttaat tctttaatga tatgaccatc tttaaaaatc aaaattctat ttgcaaaact
     5761 tgctacatag gcatcatgtg ttaccattaa aattgttgtt ttcaactcct catttgcttc
     5821 ctgtagtgag tggagtagtt cagtagctga attagaatcc aaagctcctg ttggttcatc
     5881 tgcaaagaga atactaggat gttttactat tgctctaact gctgaagctc tctgtctttg
     5941 cccaccagat aattcatttg ggtatttatt taattgagaa gctatgccaa atcgttcagc
     6001 tagactcttt accatgtttt ctattttatc tggattgagt ttctgaagtg taagaggtac
     6061 tgaaatattc tcgaaaattg taagactatc tagtaaaaaa tactcttgaa agataaagcc
     6121 taaattatcc ttacgaaaat cagcagcaca agtgtcatta agcgatttca aatttatatt
     6181 atttatgaaa atatctccac ttgttggttt atcaattgta gataatacat taagtagagt
     6241 tgttttccca gagccagaag ctcccattat acctataaat tcaccttctg atacattaaa
     6301 ggatacctta tctaaactcg gctgttgccc tttattataa gttttagtta tgttatttac
     6361 ttttaatatt gtattcattg tatatgtctc ctttcgtctt aatatagtca aattatatat
     6421 taaccttatt gtttcttcat gagtaaatca cgcaataatt ctacacaaat tacttatatc
     6481 acaatatatt gtttaaaatc taactttatt aggtttggga tgatggacaa gattttaatt
     6541 taaaagagtg cataggtata tataatggca taatgtggat ttaaattaaa aaaaataaaa
     6601 taaagccata aatattgaaa ttttcaatat ttatggcttt attgcttgta ataattaata
     6661 gaatatatat tttttattaa tcatctattt caaattctaa tattttacca gtaattgcat
     6721 taattgttat ctcatattca gtttttcctt ttattatttc accttcatat tctttgtcat
     6781 cttcatcata cttaaatttt actattttcc caccaggcac tttatctagc attattgatt
     6841 tagctttttc agcactaata atagaactgt tgtcattagt attagagtta ttcttatcat
     6901 tatcatcaaa gtcatcatca gaatcattgt ccatgtcaat atctacaatt cttccatcaa
     6961 atgcacttat ctctaattca tatgttttct tattttttat tactttagcc tcatattcgt
     7021 tatcttcagc atcatattta caatagatta aattaccatt aggaacagca tctaatgcta
     7081 tagacttagc tttatccaat gatatatttt gtgtacctaa attattatca tttaagtcat
     7141 catctttttc aatttctatt attttaccag agtaggcatc aatttctatc tcatatagga
     7201 tattatcctt tataactttg cagtcatatt cattatcatc ttcatcataa taacaaacta
     7261 aaatattgct tcctggaaga gcttgtttta atatttcttt agcctgtatt aaagatattt
     7321 ttttagtttt atttcttatg ttcacatttt ttagttttaa aatatcttca aatgcttttt
     7381 gattatatcc tcctcctact tgtgttattt catctatatc tttattttta ataaattctt
     7441 tttgactatt tacaaggcta ccattagata tcattatagg agaattttct ttagcagcta
     7501 gtactcctat tgataatgaa tctactaatg cattttcttg gttaatacca tctttagcta
     7561 caaatacatt atttattttt ttatctttat aaaatttatc aataattttt gcattagtat
     7621 tgtttctatc tgaaccactg attctttctc tgtttggata tttctttact gtattgtctg
     7681 ataaaatctt atttcctcca actatgtaag atttttttat agacctattg tttaagaaat
     7741 ttatactact atcattgctg ttttcatctg atactaatat tataggcata ttatgtattg
     7801 ctgctggaga agctatacta actgcatcag atagtccctt tagtccattt acaactgcaa
     7861 cattttctac cttttttatc ttatctattt ctttaagtac atttgtagac atttcatata
     7921 tattgtttcc tactatttta tttattttta tgttaagtga ttttatttca ttttctactt
     7981 tagaagaaat gctatttcca ctatctacaa tgtacacatt atctacacca agccttttaa
     8041 gctcagcctt agttgaattt tcaatactgt tgttgtttac taaaagtata ggtgcattct
     8101 ttagcttagc aaatggattt gcacaaagcg cactttgaat agaattacca ttaactataa
     8161 tggctgtttt tgattgaacc catcccaatt tacttacttc tactgctgtt tcatatcttg
     8221 ttttacctat taatctttct tgctttgtag tattgtctgc aaaaattgct gaagaactag
     8281 aaaaaaacat aatacctgat attaatatag ctaaattttt cttattcata tttttacctc
     8341 acaatcttta aaaatttgtt atttagcata cttaataaaa tataatctta aaatcaaatt
     8401 gatgctgagt ttgaagttac aaaatcaaca aataagattt ttttaataca aaattttcct
     8461 ttttatattt aacattgtat cacaaatata aaaaggaaaa aactttttaa aaagggtata
     8521 cactattcat tttttatctt ataaataagt ctttaccact gttttatata ttttaaaata
     8581 gacacaagac ctatttctaa atcttttagg tgaaatttct ttttaaacat atctaaaaag
     8641 tatttgtagt aatattaatg gactgaattt cttaaagtat atatttcttt acatgttgga
     8701 gtttgtgaag tttgagaatt ggagggtgaa agaaacatgt aatggattaa tattaaagaa
     8761 ctgtattttt ataatatttg tcttaaaaat aaaaaaatct attgacttga agttaactcc
     8821 aagtagtaaa gtataattat acaagaatta tatacttgta agaatagtta aagtagagag
     8881 aaaaaacaaa caagttttaa agggggaagt aaaacaatgg aggcaaaaaa attaggattt
     8941 ggattaatgc gtttaccaat aaaagatgaa aatgatgtta caactattga tatggaacat
     9001 ttaaataaaa tggtagacac ttttttagaa aggggattta catattttga tacagcctat
     9061 gtgtatcaca tgggaaaaag tgagatagca cttagagaat ctctagtaaa aagacacaaa
     9121 agagagagtt ttactatagc tacaaaactt ccattaatgg ctttaaagaa aaaagaagag
     9181 caagaaacca tttttaatga gcaattagaa aaatgtggtg tagactattt tgactactat
     9241 cttttacaca atataggcgt gtcacattat gaagtagcta aaaaatttga tagctttaag
     9301 tttattgaag aaaagaaaaa agaaggaaaa ataaagaata ttggtttttc ttttcatgat
     9361 agtgcagaat tattggataa agtcttgagt gagcatccag aagtagactt cgtgcaatta
     9421 cagattaatt atttagattg ggataatgaa agcatacaat ctagaaaatg ctacgaggtg
     9481 gcagagaagc ataataagcc tgtaattgtt atggagccag taaaaggagg tacacttgca
     9541 aagataccag aaaaagcaga gaaattattg aatgactaca atccagatat gtcaatttca
     9601 tcttgggcaa tacgttttgc agcaagtaaa gataatgtta tgatggtctt aagtgggatg
     9661 tcaaatatgg aacaattatt agacaataca ggatatatgc aaaatttcaa accattcgta
     9721 caagaggaat ataatattat agatgaagca gtagagatta tcaacgaatc aattttagtt
     9781 ccttgtactg cctgtcagta ttgtgtagaa ggctgtccaa aaaatatcgc tattccaaac
     9841 tattttgcgt tgtacaatgc agaaaaacaa gctcttaata ctggattttc aacacagatg
     9901 gtctactata ataattatac taaaacttat ggaaaggcct cagattgtat tgaatgtaaa
     9961 caatgtgaag aaagctgtcc tcaacacatt aaaattatag atgctttaaa gaatgtagca
    10021 gaaacctttg agaaataatt caatctatac aatatcaaga ggagaagata tgtatgacga
    10081 tttcagaagt tagtaaaaaa tacgagcttt cagcggatac tttacgatat tatgaacgaa
    10141 ttggtttaat accacctgta aatagaaata aaagtggaat taggtctttt acagaagaag
    10201 attgtgagtg ggttaatttc ataaagtgta tgagaggtgc aggtctttct attgagacat
    10261 taattgagta tgtagctatg tttcaacaag ggagcagtac tatcaaagct agaaaagaac
    10321 ttttaataga gcagagaaac caactagcaa aaagaataga agaaatgcaa aaaactttgg
    10381 aacgattaaa ttttaagatt gatagatatg aagaaggtat tattgagaaa gaaaaagtat
    10441 taaagagcag tagaaataag aaaatggagg cagtatctta tgagtaaaaa tgtattaata
    10501 gtatcagcta gtcctagaaa aggtggaaat tctgatttat tgtgtgacca gtttatacaa
    10561 ggggtattag aatctaaaaa tcaagtggag aagatatttt taaaagataa agatattaac
    10621 tattgtactg gatgtggtgc ttgttatgaa aaagaagcaa attgttcaca gacagatgac
    10681 atgggagaaa ttcttgaaaa aatgattgag gcagatgtga ttgttttagc gactccagtt
    10741 tatttttata ctatgaatgc gcaaatgaaa actatgattg atagaacttg ctctagatat
    10801 actgaaattt gtgataaaga tttctatttt atcgttacag cagcagatga aaatgtggct
    10861 gatatggaaa gaacaataga aggatttaga ggatttacat catgtctaaa tggttctaag
    10921 gaaaaaggta tagtatatgg tgtaggtgct tggaatgtag gtgatattaa gggaagtaag
    10981 gcaatgaaac aggcatatga aatgggtaag ttggcgtagt atgtttgtat aaaattgtat
    11041 aaaattgaat atattcttat catttcaaca ataaaaagag gcttatctgt attttgagac
    11101 agcctctttg tgctatatca tttattttta ttctatatcc ttattatacc ctttattttt
    11161 ttatgcctat ttaagtatct gttgttactc atatatttta ataattaccc ttaaaaaact
    11221 atacagattc ctgcataata ttattttctt tagtaattaa tttttctagg tttttccaat
    11281 ccatttcttc catatttgca aaataatgac cacttcctat gcaagtcagg taagactttc
    11341 catctaattc aaacgaagaa cctccaatac actttgaatt acatttctta caagtacgag
    11401 ttttagttat actatcttta atagttttag agcattcctc cacagcatct ttatatgtat
    11461 ttagatgaaa aagatttgct ttaactctcc attttttttc attacattca atagtaaata
    11521 agctacgttt tggtttctta gttgaatata ctattttgta agaacgagca cctgtttttg
    11581 gttcaatttt acaatctaat gatttaccaa gttcatgtaa atgacatgca atatcataat
    11641 ctttaccact tagtacttct aacatttctt ctgttgtttc tgctgttaat tcacttttgc
    11701 tcatattaaa aaaatccccc tatataaata ataatttcat atgaaaataa ttaatataag
    11761 tatattaaat aaaactatta aaatcaataa aattactgca atcttacatt attgggcata
    11821 gaatgagagc taatgattta ttagaaataa gacttaatag tatgaaaatt tacttagacg
    11881 tggtacaatt ctataaaaga tttaaaacta ggaaaggaga aagttgttga gatacggcca
    11941 atataacaat ttatttataa gttgtaaatt tattatgaga ttaattagat tgttaagtaa
    12001 tactatcaaa aggtagtttt ttggattttc agcaacagtg gtagatattg ataatttttt
    12061 ggttattatt atatttagct gttatatttt caataggctc tatgataact agggtaaata
    12121 aggtatgggt aaaggtttta ttatttataa tagtgggatt gtcaactata gttctttcat
    12181 atgtaataac ttgattatgc aaaattctat gaagcaggaa ccctgtgact ttagtcatgg
    12241 gaggttcaga atttaaggtt aaaaaataac tttaatctgt aaattctcaa aacaagaatt
    12301 ctcatgttgg taaatttcta gatatgagaa aaaaattgac atcataaaaa agtaatttta
    12361 gagcgttttt ttacgaaaaa attcagaagt aactattttg aatgacttca caaaatttta
    12421 tatataaata aagtttggca cgttaattgc tttaataaaa gttaacaaga cacaaataaa
    12481 cataatcatc taagtattga ttatttgaag ttttagattt gaagtttaat ctaaaggttc
    12541 gtattaatat tggtgtttag gaaattttat tttcctgtaa atataactta ataataggag
    12601 gtgaagtcat gtcaaaagta gtaatagcta cagagaaagc tccaggagca attggaccat
    12661 attctcaagc aattcaagtt ggaaacatag tttctacatc aggtcaactt ccaatagata
    12721 tgaagactgg cgagttagta tctgacccaa aagaagcaac aaaagcttct ttagataatg
    12781 taaaagcaat attagaacaa gctggtacaa gtatggataa aatatttaag actacagtat
    12841 tcgtaaaaga tttaaaggat tttaatgata ttaatgaagt atatgctaca tattttaaag
    12901 aaaatccacc agcaaggtca tgtgtacaag ttgctcaatt accaaaagat gcagttttag
    12961 aaattgaagc aatggcagta ttataagtat tataacaata aaaccaataa caaaactaat
    13021 aaaaattaaa aactaataaa aaaagtctac aattaaaaaa gtttatatta aaaaagtcta
    13081 tataaaaatc tatctaaata tttaactatt gagcttttct catataatgt atatttttat
    13141 gtcaaaaata tatttgttat atgaggaaag ctttttttta ttattgtatt gtgatttatt
    13201 ttattgtctg catattataa ttaaggttac tatataaaac aaacttttta taaattaata
    13261 ttgtctgttt taacgcaaat atataaataa gtaatgtttt atatatattt taaagagtga
    13321 ctatatgtta aaatatagct aaactgataa tttggtaaat taaattctaa tgggggaaac
    13381 tatgttaagt aaattaaaag aatttcaaca agaaatgata aaatacactg aaacagtagc
    13441 tagtgtgtta gatgtagata ttgaaatagt tgacgataga ttaataagaa ttagtggtac
    13501 aggtctgtat aaatcaaaga taaatgaaag cgttgttact gagggcttta tttatgacaa
    13561 tgttatacag acaggtcagg aattagtcgt attggatata tgtgataatc agctttgtat
    13621 agaatgttcc cattacatga aatgcctaaa taaagtaata atagcagttc caataaagta
    13681 taataatcga actataggag taattggtgc tattagtaca gataaaacta aaaaagtaga
    13741 aataagtgca aaaatagata attatttaaa atttgtcaat catatatgcg atttaatttc
    13801 tatgaaaata gaagaacatg aagcgtcaaa aaatagcagt agaaaaatgg atatgatgat
    13861 agaaatcatt gaaaatgttg aaaaaggcgt tataatacta gacataaata gcaaaatatc
    13921 ttatataaac aatatagctc taaaaaaatt agatatagat aaaaatataa tagaaaatat
    13981 agtaaatata gtatctgttg aatcttcctc aaatggacat gaattactag aaattgatat
    14041 tgataacaaa atttataata taaatgccaa aataattccg gtatatccat atataaatca
    14101 atacgacaaa ataataatat ttgacaagac atatatcaat cataaaggac atggaaaagt
    14161 gaatagtggc tggggaaata gtgatataga gtctataatt ggaaattcag aagcaatgtt
    14221 aaaagtaaaa gagagaacta agaaattagc aaagtcaaat tcaactgtac ttataactgg
    14281 ggaaagtggt acgggtaaag agctaattgc tagggctata catgctgaag gtagcagatg
    14341 gaacaagcca tttattgcga taaactgtgc tgctattcca gaaaatctcc ttgaaagtga
    14401 gctatttggc tatataaaag gtgcatttag tggagctagt agtggaggta aagtaggtaa
    14461 atttgaactt gcaaatgaag gtgttatatt tcttgatgaa ataggagatt tgtcaatgcc
    14521 tttacaagca aagttactta gagttttaca agagagaaaa tttgcgagaa ttgggtcaaa
    14581 taaacttata gatttagata taagagtgat tgctgctaca aataaaaact tattgaaatt
    14641 agtaaatgaa ggtaagttta gggatgattt atactataga ttgaatgtaa ttcctataaa
    14701 tttgccacct cttagggaaa gaaaggatga tattgaggca ataatgatga agtttgcttc
    14761 taaatattct ttagaattag gtattcagtt aaataaaata gaagaaaatg taatgaatat
    14821 gttgattaac tataattggc cgggaaatat aagggaactg gaaaatgcag ttgaatatat
    14881 gatgaatttg gttggagatg atggaataat atataaagat atgcttccat tagatatttt
    14941 aaactattat aatattaatg gaaatattta taaaaataag gatgtaaata taatatttga
    15001 agatgatata gttggaggga tagtagagaa tcaagaaagg atactttcaa ttaaagaatt
    15061 agagttgact tacataaaca agttgttgaa taagtatgga agagatacaa agacgaagaa
    15121 gaagatagca aaagacttag gcataggttt ggctacacta tatagaaaat tggaagagga
    15181 acagtagtaa tataatatta aaatgatagg tatttgtgtg tttttataga taggtatttt
    15241 tactttatgg tggaggtgtt attatgcaat atgcgataga gctgtattat gataaaaaaa
    15301 cggaaaagca actttttgat ttatctaaaa aaatcgctga tgaaaaaatt agtacgaagt
    15361 atttagaatg gaaaacaaga cctcatctta ctttggcttg tttcaatgat gtggatgagg
    15421 cttgttgtat agacaagcta aaggggtttg cacaaaacca taaggtaata cctgcttaca
    15481 ttggttcagt aggcatgttt aatgatacta aaacggtgtt tgtatcacct ataatgaata
    15541 gcagtatgta gcagtttcag agagaattat atgaggtact acaagatttt gattcaaatg
    15601 gttgggaatg gtaccacccc aatcgttggg taccccattg cacaatagca cttactggag
    15661 atgatgaaag tgaggctttt tttcgggcaa gtgatgtatt actgcgtgag ttcaaaaaaa
    15721 taagtggtga gtttgtctca ataggattgg ttaaaattac atttcctgtg gaagaaattt
    15781 ttacagtgaa tatgaatagg taactttaac tctgttgtgg atgttatgaa tattttgtat
    15841 agtgcatttc atcagataaa tgcgaagttg cgaatttcga cagctcaata gtcgcaagta
    15901 gggcacaatg gtacacatat tgcacttttg cttattgggg ggacgcccat gtaaacttct
    15961 gtaagaagct atgaaaagat ttaagccatt ttggaggctt tgggtaataa agaatatttg
    16021 ggtaataaag aatataaagt atataaattt atagagttta tgcgtaagaa ggttatagcc
    16081 atatatttat agaaaataaa agtagtaata tatctgacaa aacaatagac atataaaaaa
    16141 taagagcata ataaaggaag aattaagata aataaacgat ttctcgaatt gataattctc
    16201 gtattgataa aaatttccca atatgagaat tttttctttt ataaatctta tttttcacac
    16261 tcaaaattta taaactttaa agaaatttta taaaagtatg taattccaac ataaaaaaat
    16321 tgtttttaga ataaataata ttggcacggt aattgctttg ctataaggca caaagataaa
    16381 aaattaaaat gacaccgaaa aatttgaaag gggaatataa aataaatgag agaaataaaa
    16441 tggaaattaa ataacttacc taaatcagag gaaaaagaaa aaggaattga atttttaaaa
    16501 gatgaagaga ttgcaaaggc taaagctttt catgaaagct ttccacaata tgaaaaaact
    16561 cctttagtta aattagataa cttagcaaaa tcactaggcg taagcggaat atatgttaaa
    16621 gacgaatctt atagatttgg tttaaacgca tttaaagttt taggtggttc ttactctatg
    16681 ggtagatact tagctcaaag attagataca gatatatctg agttagggta tgataaatta
    16741 acttcaaaag aaataaaaga aaaattagga gaaataactt tctttacagc tacagatgga
    16801 aatcatggta gaggagttgc ttggacagct aataaattag gtcaaaaatc tgttgtatta
    16861 atgccaaaag gttcttctga atttagatta aataaaatca aaggagaagg tgcagatgct
    16921 agtataacag acttaaacta tgatgatgca gtaagattag ctaatgatta tgcagaagct
    16981 gatgaccatg gagtaatggt tcaagataca gcatgggacg gatatgaaga aataccagca
    17041 tggataatgc aaggatatgg aactatggct aaagaagcta tagaacaatt aaaagaatat
    17101 ggagtagata gaccaacaca cgtatttgtt caagcaggag ttggttcact tgctggtgca
    17161 gttcaaggat atgttgcttc aatatatgat gaatgcccaa taacagtagt agtagaggct
    17221 gatgaggctg actgttacta taaatcagca gaagctggag atggaaaacc aagatttgtt
    17281 ggaggagata tgccaactat aatggcaggg cttgcttgtg gagaaccaaa cactataggt
    17341 tttgaagtgt taaaaaatta ttcatcagca ttcgtttcag caccagactg ggtatctgct
    17401 aaaggtatga gaatattagg aaaccctcta agaggagatg agaaagtaat ctctggagaa
    17461 tctggagcag ttacaactgg agcattagtt tcaatccttg aaagtgaaga tttaaaagac
    17521 ttaagagaag ctttgaaact agatgagaac tctaaagtat tattaataag tacagaagga
    17581 gatactgacc ctgataaata tagagatata gtttggaatg gtgaatgcca aagtaaataa
    17641 aagacttaag gaaaagaaaa tcttaacaaa taaatgaaaa atttaaggaa aataaaaact
    17701 taaataagtg aaaactttaa ataaaataaa aactaaaaca aatgaaaaat ctaaataaat
    17761 gaaaaagtaa agcaaataaa aaagtaaagc aaatgaaaaa ttcaaaataa aaaccaaata
    17821 aaattaaaat aaagtctaaa taaaaattta ataaataaaa tataaagaaa taaaaaatca
    17881 atagattaag tgaaatgcta ataaattaaa aaaatgaaat atcaaaataa aacgtcaaca
    17941 aattaaaaat tatatggggg aatatcaaaa tgttaaatga aacaagaaaa aaacaattaa
    18001 ctgaagtatg ccaagactta ataagaaatg ctagttattc aggtcaagaa gaaaacgtag
    18061 taaaagctat agaagaaaat tttgctttac taggttttga tagttggtca agagatagat
    18121 atggaaatat agtaggatgt ataaaaggaa ataaaccagg taaaaaaata ttatttgacg
    18181 ggcatataga tacagttcca gttccagatg caagtaaatg gagtgttcct ccttttgaag
    18241 cgagaatagt agatgggaaa atatatggta gaggaacttc tgatatgaag gggcaagtaa
    18301 gtgctatgat ggctgctgtt tcatactttg cagaagatac taacaaagac tttgaaggtg
    18361 aattgtatgt agcaggtgtt gttcatgaag aaatatttga aggtgtttca gctagagaga
    18421 taagtaaggc tgttcaacct gattatgttg taataggtga atcttcagaa ttaaacctaa
    18481 agataggtca aagaggtaga ggagaaatag tagtagaaac ttttggtaaa ccagctcact
    18541 ctgctaatcc agaaaaaggt ataaatgcag tttataaaat ggctaatgta atccaaaaga
    18601 tacaacaatt agtacctcca actcatccag ttttaggtga tggaatatta gttttaacag
    18661 atataaaatc ttctccatat ccaggagcat cagtagtgcc agattattgc aaagctactt
    18721 ttgatagaag attattagtt ggagaaacaa gagaaggcgt attagctcca atacaagctt
    18781 tattagatga aatgatgaaa gaagacccag aattaaatgc aaaagtttct tatgcagttg
    18841 aaaaagctga ttgctataca ggaaatacta tagaaagtga aagattcttc ccaggttggc
    18901 tatatgatga agaagatgaa tttgttcaag cagcgtataa gggattaaaa gaagctggaa
    18961 tagattcaga aataactcaa tactcattct gtacgaatgg aagtcactac gcaggtgagg
    19021 ctggaataag aactatagga tttggtcctt ctaaggaaaa tcttgctcat acaatagatg
    19081 agtatataga attagaccaa ttattcaaag gtgcagaagg atattatggt atattaaaat
    19141 cagtttataa aaaataatta ggagatggtt ttgtgagaat tttaataaaa catgggctta
    19201 tagtagatgg aaataaaaca ccagcatatg aaggagatat tttaatagaa aacgagaaaa
    19261 tattaaaaat atcacaagat ttaaacgaag aagctgacaa agttatagat gcaaaaggta
    19321 gagttatatg tccaggtttc atagatactc atagccattc agacctagtt attttagtta
    19381 atccatataa tgaggtaaag attagacagg gaattacaac agaagtgttg ggccaagatg
    19441 gtatatctat ggcccctcta cctcaagagc atatatcttc ttggagaaaa aatttagcag
    19501 gtctagatgg tgaaagtgat gaaattgatt ggaaatatga aacaacagag aattatttaa
    19561 aaatgatgga ttacaatggg gtaggtttaa atgaaactta tttagtacct catggaaacg
    19621 ttagaatgga agctatggga cttgaagata gacctgctac taaagaagaa attcaaaaaa
    19681 tgtgtgaaat cacagagaga gaattaaaag caggagctat aggattgtct actggactta
    19741 tatatatacc ttgtgcatac tcattgactg aagaaattat agagatgtgt aaggtagtag
    19801 caaaatatga tggagtattt gtagttcacc aaagaagtga agcagataca attttaactt
    19861 caatggaaga aatcatagaa attggaaaac aatcaggagt aaaagttcat ttttcacatt
    19921 ttaaggtttg tggtaaagca aactggaagt atataccaca agttatagag cttttagaaa
    19981 aagcagaaaa ggaaggaata agagtatctt ttgaccaata tccatatgca gcaggaagta
    20041 caatgcttgg agtagtttta cctccttggg cacattctgg aggaactgat aagttaatag
    20101 aaagattaag tgatgaaaac gaaagagcaa aaatgaaaaa agatatagca aatggaatag
    20161 aaggctggga taattttata gaatttgctg gaatagacca aatatttgta acaagcgtaa
    20221 aaacagaaaa gaataaagat acaattggta agaacttatt agaaattgga aaaatgagag
    20281 gaaaagaccc attagatgca acgtttgatt tattaaaaga agaagaaaat gcagttggga
    20341 tggtagattt ctatggatta gaagaacata taataggatt catgaaaaga gacgagcaaa
    20401 atgtgtgtac agatggtctt ttagcaggta aaccacatcc aagagcttat ggttctttcc
    20461 ctaaaatact aggaagatat gttagagagt tgaatgtgtt aacaatcgaa gaagctgttt
    20521 ataaaatgac taaaaaggca gctacaagct ttagtataaa agatagaggc gaattaaaag
    20581 aaggatattt tgcagatata gttatatttg acaaggatac agttagtggt tgtgatgatt
    20641 ttatcaactc tatgcagtac cctacaggta tagattacgt aattataaat ggaaattgtg
    20701 ttgttgaaga aggaaaatac aataaaatta aagcaggaaa agtacttaaa aattaaatct
    20761 tagctttaag gaggaataaa tttatgattt tagtggggaa tgggaggcta ataagccaag
    20821 attctttaaa tccctatatg gaagatggat gtgtagtaat aaatgataat ctaattgaag
    20881 atataggtac tacagaagaa atgaaagcta aatatccagt acatgaattt atagatgcag
    20941 gcaagaaaat aatcatgccg ggtctaataa attcacatat gcatatatac agctcatttg
    21001 ctagaggaat ggcagttcca ggaaaacctt ctgagaactt tttagagata ctaaacaatt
    21061 tatggtggag acttgacaaa cagcttacac tggaagatac aaaatacagt gcatatgcaa
    21121 cgtatataga atgtataaaa aatggtgtaa caacagttta tgaccatcat gcaagtccaa
    21181 atgcaattga aggcagtttg tttacaatat cagatgttgc aaaggatttg ggaattagaa
    21241 cgtgtctttg ttatgaagtg tctgatagag atggtggaaa tacaatccaa caaggtatca
    21301 atgaaaacgt aaactttata aaatacgctc aaaaagatga tacagacatg ataaaaggaa
    21361 tgtttgggct tcatgctgca tttacactat ctgatgatac attaaataaa tgtgcttcag
    21421 agatggctgg tcttgataca ggttaccatg tacatgttgc tgaaggacta gcagacttac
    21481 aatataatgt agataaatat ggaaaaaggg ttttagaaag attcaatgat tttggagtac
    21541 taaaagaaaa aacaatagca gttcattgta tatatataag tgcagaagaa atcagtcttt
    21601 taaataaaac aaatacattt gtagttcata atccagaatc taatatggga aatgcagttg
    21661 gatgttctcc tgcaatagag ttattaaaaa ggggagttac agtaggatta ggaactgatg
    21721 gatatactag cgatatgttt gaatcattaa aagttgccaa tataattcac aaacatcact
    21781 taaaagaccc aagagttgga tttgaagaat cacaaacaat gttatttgat aacaatagaa
    21841 aaatagctaa agcttattat aaaaatgacc taggagtact taaaaaaggt gcttatgcag
    21901 atgttatagt agttgattat ataccacata ctccattgac agaaaataca atagggggac
    21961 acactatttt tggaatgagt ggaagaagcg tagatacaac tattataaat ggaaaggtac
    22021 ttatgaaaga tagaaagtta ataaacatag atgaagaaag tattctagca aaaagtagag
    22081 aattaagtca aaatctatgg aatagaattt aaataattga ttatgcaaaa ttctatgaag
    22141 caggaaccct gtgactttag tcatgggagg ttcagattaa tatacaagta agaaacaaga
    22201 atttagatgt taaaaacaga gcttaaacaa aaataggaat ttaaatgaag tatataaata
    22261 aaaaatatac ggaatagaat attaaattaa atatagaagg gagacccaaa atgtctcgag
    22321 ataaaagccc taaaatagct ccagtagatg aaaggttacc tgtatccaaa tcttgggtat
    22381 tttcactaca gcacgtttta gcaatgtgtg caggagcagt agcagttcct atgatgatag
    22441 gaagtgctgc acgactagat catgctagta ttgttttttt aataaatgct tgcttgttta
    22501 tggcaggtat aggaacactc atacaaagtg ttggtatagg aaatattgta ggtgctaaaa
    22561 taccagtaat agaaggaact agttttgccg ctgtggcagg tatgacagca atagcctcat
    22621 catatagtga ttcacaagtt gcaatacaga cagtatttgg ctctgtaata gtagctggat
    22681 tgttttgtat attacttgct ccagtatttg aaaaattaat aagatttttc cctagtgtag
    22741 ttactggaac agttgttatg gtaataggta tttcactatt tccagttggg ataaaatgga
    22801 taactgacaa caaattggaa gcggttgaac caaactcatt agcattagct ttagcagtat
    22861 tggcaataac tttactttca tttaaattct taaaaggaat ttggaatagc acagctatat
    22921 tggtaggtat agtacttggt acactacttt ccatggcagt tggaatggca gattttagtg
    22981 cagtaaatgg agttggttgg cttaacttaa atgtaccttt aaaatttgga atgcctagat
    23041 ttgaaccatc tgcaatacta tcattgtgtt tgattatgtt ggtacttatg acggaatcag
    23101 ttggtaatat gatagctatt catgaaatgg tagacaaaga agtaacaggt aaaaatatta
    23161 aaagaggtct atttggagat ggaatatcta cagcattatc tggaatattc aattcatttc
    23221 caataactcc atttggtcaa aatacaggaa tagtaggtct tacaggtata aaatcaagat
    23281 ttatagcagt ttacgcaggg gttatattgc tagtacttgg attcttacca aaatttgcag
    23341 caataatagg agcaatacct aagcctgttc ttggaggcgt aggatttgca atgtttggaa
    23401 tggtaatggt tggaggagta aaaactttaa gcaaagtgaa atttgatgga actaaaaatg
    23461 gggttatagt agcagttagt gttggtttgt ctatgatacc actaacaaat cctgatttct
    23521 atcataattt cccaacttgg gtacaaacaa tattccatag tggaataaca acaggtagtt
    23581 tatcagcagt gcttttaaac atattcttca atgaactagg ttctaaaaaa gaaaaaaata
    23641 ataaagttga agaagcaaaa taaaaataaa acaagtaaaa atctatattg acttaaagtc
    23701 attaagtatt aataaaaata attcagagat attaataatt caacaaaact atcttatatt
    23761 ttaaataata taaaaaagta aataaataac aaatacaaat aaaagaatac aatctaaata
    23821 ttaaaaatat ttaatttaag ggagagataa taatatggct aatttaaaag ttaatttata
    23881 tggaatggaa tttttaaatc caattatgac agcggcagga cctggagcaa aagatggtgc
    23941 tctctgtcaa gaggcagcaa aaggtggagc aggagctata tgtacaaaaa ctatatctgt
    24001 attaccagct gatgtaccaa gaccatgtat ggcaaaaact aatagtggtt ttttaaacac
    24061 agaattatgg tcagagcttc caaaagagca atggatagag gaagaataca aaaaggtaaa
    24121 agaaacaggg cttccagtaa tagtaagtat gggatattca gcagagcaaa tagctgaggt
    24181 tgctccttta gtaaagcctt atgcagatgc agttgaatta tctactcatt atgtaggtac
    24241 agacgttgca ccaatagtaa atgctttaaa agctgcaaaa gctgttttag atgtaccagt
    24301 atttatgaaa atgagtcctc atactgacat tcaaactatt gcaaaagctg ttgaagaagc
    24361 aggtgcagat ggacttgtaa tgataaactc atttggacca tgtatggcaa tagatgtaaa
    24421 tacaggatac cctataatgg gaagtaaagc tggatacgga tggttatcag gtgcaccaat
    24481 aagacctcta gcaataagat gtatatatga agcttctcaa gttgtaaata taccaataat
    24541 cggtgttggt ggaatcactt gtggaaaaga cgtggctgaa atgatgatgg ctggagcaag
    24601 tgctgttcaa gtatgtacag aagcaatcct taaagggcct tctatctatg gaaaaattgc
    24661 taaagaatta aatgaatttt tagatgagaa tggatatgct gatgttaatg aaataaaagg
    24721 actaactcat aagaaaatgg cagctagagg gtttagaact cattcagtag ctccagtagt
    24781 ggatgataac aagtgtatca aatgtaagca atgtgtaaca agctgtgtat acgaagcttt
    24841 agaagttaca gataagttga acatagatgc agacaagtgt tttggatgtg gattatgtgt
    24901 aactagatgt ccaaaaggag ctttaagcat ctgctacaat caagtagaag ctatgaatga
    24961 gtaataatta tatagaattt tggtaattaa cttagagtaa taggtattag gataataaaa
    25021 tatatcagat aaacaaacac acattatgca ttaataatac agtctaaagt taataatttt
    25081 attatattga tttaactaaa tattagttta gctgaatatt aatttaatta ggtattggtt
    25141 taatcttaat atagatttac tgcgtataag tgaactaact agattacttt aagttaattt
    25201 tttcatataa aataaattga tacattacaa gtaaggtgga gtctatatgg gaattgtttt
    25261 aaaaggtggg aaagtagtaa caagtgaaaa aacttactgt gcagatgtaa gaatagaaga
    25321 tgaaaaaata gtcgatatag gtcttgatat atcaaaagaa aatgatgaaa tagttgatgt
    25381 tagtgattct tatgttatac caggaggtat agatacacac acacactttg acttagatac
    25441 aggcgttact aagacagcag ataactttga gacaggaaca aaagctgcta tagtaggagg
    25501 aactactact atattggatt ttgctacaca agctaaagga tgttctttga aagacggatt
    25561 agaagaatgg catgaaaaag ctaaggataa atcctattca gattatggct ttcatatggc
    25621 tataacagat tggaatgact cggtttgtaa tgaaatggag gatatggtga aagagggagt
    25681 atcttcattt aaactgtata tggcgtataa aggaagcctt caagttgatg atggtgtaat
    25741 ctttgaagca ttgagaaaag cagaagagat aggagggatt attggtttcc attgtgaaaa
    25801 tggggacata atatgtgaac ttgtggataa agcaaagtca gaaaataatt tatctccaaa
    25861 atatcatcaa ttaactagac cagctataat ggaggcagaa gctacatcaa gacttatgaa
    25921 gatagctgaa gttgcaaact ctaaagtata tgtagttcac ttaagctgta aagaatcctt
    25981 agaggaggtt ttaaaagcta agcaaagagg tgtggatgta atagttgaaa cttgtcctca
    26041 ataccttcta ttaaatgatg aattatatga tttagatgga tttgaaagtg ctaagtatgt
    26101 aatgtcacca cctttaagaa ataaagaaaa taatgaaata ttatggaatg ctattttaga
    26161 taatcaaata gacactatag gaacagacca ttgttctttt aattataagg gacagaagga
    26221 acttgggata aacgatttca gtaagatacc aaatggttct ccaggtgtag aacataggat
    26281 gagtctttta tacacatatg gagtctgtaa aaataaaata tctatcaaca agatggtaga
    26341 agtaacatca actaatgcag caaagttgtt tggaatgtat cctaataaag gaactataga
    26401 aataggcagt gatgcagata tattagtctt aaatccaaac aaaaaatcca aaatagaagc
    26461 aaaaaaacaa ttacaaaatg tagattatac accttatgaa gggtatgaag tggattgtca
    26521 aatagaacat gtttatttaa gaggaaaaga agtagttaga gatggagaat taatttgtaa
    26581 tactccaagt gggagatata taaataggcg tctaacaaag ggggctagag aatggtagaa
    26641 tttatattaa atggagagaa agttgttgca aaagaaggca aaaaactttt agacttcctt
    26701 agagaagata tgaatataac ttcagttaaa aatggatgtt cagaaggtgc ttgtggaaca
    26761 tgtatggtta taatagatgg taaagctact aaagcatgtg tatttaaaac tgataaatta
    26821 gctgggaaaa acataacaac tatagaggga ttatcagaga gagaaagaga tgtttttgca
    26881 tattcttttg ctagtcaagg agctgtacaa tgtggatttt gtattccagg tatggtaatt
    26941 agttcaaaag cacttataga cgttaataat aatcctactg aagatgatat aaagaaagct
    27001 ttaaaaggta atatatgtag atgtacaggg tatgtaaaaa taattaaagc tgtcgattta
    27061 gcggcaaaga tttttagaga aaatatagat gtgccaaaag taaactgtaa gggtctagta
    27121 ggtgaaaatc ttcctagagt tgatgcagtt ggcaaagcac ttggatattc tgaatatgta
    27181 gatgatatga gaattgaggg tatgatttat ggttcagcag ttagagctaa gtatcctaga
    27241 gctttagtta aaaaaataga tatagaagaa gcaaaagctt atccaggagt tgttgcagtt
    27301 ctaacagcta aagatattcc aggaactata aaggtagggc acttaaagaa ggattgggat
    27361 actttaatac cagaaggtga aataactaga tacttaggag atggaatagt tttagtagca
    27421 gcagaaacta gagaagcgtt agaagaggcc aaaaagctag ttaagataga ttatgaggaa
    27481 ttaacaccat taagtactac agcagatgca cttagagaag atgctccaaa gatacatgag
    27541 acagggaata tacttgttaa ggaacattta gtaagaggaa acgctaaaga aaagatagaa
    27601 aattcaaaat atgttgtaac taaaagatat actacacctg ctacagaaca cgcattttta
    27661 gagcctgaat gtgcagtagc tggtccttat gaagatgatg gagtaataat ctattcgaca
    27721 gaccaagggg tgtttgccac tcaacatgaa tgtgcagata tgttagggtt accatatgag
    27781 aaggtaagag ttataaacaa aatggtagga ggagggtttg gtggaaaaga agacatgagt
    27841 gttcaacacc atgcagcctt acttgcatac catacaaaga gatttgtaaa agtacagtta
    27901 acaagaaaag aaagtattat tgttcatcca aaacgacatg ccacagaaat ggaatttacg
    27961 acagcatgtg atgaaaatgg atacttaacg ggtatgaagg caacgataat atctgacaca
    28021 ggtgcatatg cctctcttgg aggaccagtg ctacaaagac tgtgtactca tgcagcagga
    28081 ccatacaatt atcaagatat tgatataaca ggaacagcag tatatactaa taaccctcct
    28141 ggaggagcat ttagaggatt tggagttaca cagagttgtt ttgcaactga atgtaatcta
    28201 aatttacttg ctgaaatggt tggaatatct ccttgggaga taagatataa aaatgcaata
    28261 agacctgggc aagttttacc aaatggtcaa tttgcagatg aaggaacagc aatggcagag
    28321 acactagaag ctgtaaaaga agagtatgaa aagcatccac gtgcaggtat agcttgtgct
    28381 atgaaaaata gtggggttgg agttggtata cctgatgttg gaagatgtag attggtgata
    28441 aaagatggca aagttcacat aagaacaagt gcttcttgta taggtcaagg gcttggtact
    28501 gttatgactc aagtagtttg tgaaactgct aacctacttc ctgaaaatat agttcatgaa
    28561 gttccagata ctcatttaac accagactct ggtaatacta cggcttcaag acagacagta
    28621 tttacgggag aagctactaa ggttgcatca aataagttaa aagaagcttt agactctggc
    28681 aaaactttac ttgatttaga gggagaagag ttttatggag aatatgaaag tattacagat
    28741 aaaatgggtt gtgacaaaga aaatccagta agtcatgttg cttatggata tgcaacacaa
    28801 gttgtaattc tggatgaaaa tggaaaacta gaaaaagtag tagcagcaca tgatgttgga
    28861 agagctataa atccaatcag tttagaaggt caaatagaag gtggagtagt tatgggtctt
    28921 ggatatgctc taaccgaaga ttacccagta gttaactcta ttcctacagc taagtttggt
    28981 acattaggtt tatttaaatc tacagatata ccagaaatac aagctttaat agttgaaaag
    29041 aacaaagatt tattggctta tggggcaaaa ggtgtaggag aaatttgtac agttcctact
    29101 gcaccagcag tacaaaatgc ctattatgta tttgataaag aatttagaac tgagttacca
    29161 ctacaaaata ctccatatag taaaaaaaag taacaaaaaa aagaaatatt aaataaaaaa
    29221 atagatgaaa ttgtaaataa aaaaaaccct tttgcataag gtatatttta aatgatagaa
    29281 tatacatata caggagggtt tttcttttat aaaataagtt taataaaatt gagaggtgag
    29341 cagaatgaat tttaataata gtctagaatt aactcagtct cagaagctaa taatgactac
    29401 acaacttaag caatcattat caatattaaa tatgagtaag ttagagttag aagaagagat
    29461 aaaaagagaa gcagagaata acccattagt tgaagtcgag aaaagtgggg agataaattg
    29521 ggaagagtat ataaaagaca tggataggtc aagacgttta gatagaacag agataagcta
    29581 taatcctgat aatgaagtta atctagaaaa tttagttaaa tattcgtcaa atttatatga
    29641 agatttaaaa tttcagataa gcctgtataa acttacagac aaagaattgg aagtctgtga
    29701 gtatataatt gatagtttag atgaggatgg atatttaaga actgaggaaa aagtaattgt
    29761 tgatacctta aagatagatg aagaactttt tgaaaaatgt ttaattagtg ttcagcagtt
    29821 ggaacctagt ggagtagggg caagaagtct ttcagaatgt ctgatgatac aaatggctag
    29881 tttaggaata tataatgaaa ttttagagga aatcgttaca aaagacttaa atttaattgc
    29941 aaataataaa tacaaagaga taagtaaaaa gtacaatatg tcattacaaa aatgtgttga
    30001 actaataaat ataattaaga cattagaccc caaaccagga agaacttgtt cagtagagaa
    30061 aagtgtatac attcaacctg atgtaacagt agaaaaaatt gatgatgaat ttattgtata
    30121 tttaaatgag aaagattctt atcaaataag aatcaatagt tattataaag acatattaaa
    30181 aaattcacag tctgatgaaa gtgcaaaaga atttataaaa gaaagactaa attcagcaac
    30241 aggacttatg aaaaatatag agagtaggaa aactacagta cttaagattg cagaagagat
    30301 agtaaaagct caagatgaat ttttgagaaa agggacaaaa tatataaaac ctttgaaaat
    30361 gaaagacata gcagaaaaat tagaatttca tgaatctact ataagtagag gtgtaaatgg
    30421 taaatatatg ctaacacctt ttggcgtata tgaatttagg tactttttca gtagcgccat
    30481 tgagactgag aataatgaaa tggcatctag tacaagcata aaaaaaatta taaaggaaac
    30541 aataaaagac gaaaataaaa agaaaccttt aagtgatgac catatatcta agttattaaa
    30601 agaaaaagga atcaatgttg caagaaggac agttgccaaa tatcgtgaag aattaggaat
    30661 cccatcttca agtaagagaa aagaatacta ataagtaaaa gacaaatatc agtatggtaa
    30721 ggggaaaagg ctaattaaga gatgaatgta gattgggcta aaaattttat aaagtaaaat
    30781 aatataatat gaaaaagtat taaaatgcta taaggtatta aaaaactggg gaacattaaa
    30841 acattaagat agcaaagagc ataaaaaact aaagaagatt aaaacattaa agaacattag
    30901 agctttgagg aatattagaa ctttaaagaa tattaaaatt tataaaatat aaaaat
//
LOCUS       DAEHWO010000047        30676 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEHWO010000047 DAEHWO010000000
VERSION     DAEHWO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30676
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.047"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            99..2000
                     /locus_tag="KNP54_002434"
     CDS             99..2000
                     /locus_tag="KNP54_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0893314.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2003..3046
                     /gene="ypdE"
                     /locus_tag="KNP54_002435"
     CDS             2003..3046
                     /gene="ypdE"
                     /locus_tag="KNP54_002435"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBF0893315.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNKKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3061..3366
                     /locus_tag="KNP54_002436"
     CDS             3061..3366
                     /locus_tag="KNP54_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBF0893316.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3463..3798
                     /locus_tag="KNP54_002437"
     CDS             3463..3798
                     /locus_tag="KNP54_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0893317.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3830..5152
                     /locus_tag="KNP54_002438"
     CDS             3830..5152
                     /locus_tag="KNP54_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0893318.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILSNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEGLLDDLGLDF"
     gene            5162..6232
                     /locus_tag="KNP54_002439"
     CDS             5162..6232
                     /locus_tag="KNP54_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBF0893319.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIKLIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6237..7424
                     /locus_tag="KNP54_002440"
     CDS             6237..7424
                     /locus_tag="KNP54_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBF0893320.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7621..8493)
                     /locus_tag="KNP54_002441"
     CDS             complement(7621..8493)
                     /locus_tag="KNP54_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBF0893321.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(8887..9078)
                     /locus_tag="KNP54_002442"
     CDS             complement(8887..9078)
                     /locus_tag="KNP54_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893322.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9298..10344
                     /gene="cobT"
                     /locus_tag="KNP54_002443"
     CDS             9298..10344
                     /gene="cobT"
                     /locus_tag="KNP54_002443"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBF0893323.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10376..10936
                     /gene="cobU"
                     /locus_tag="KNP54_002444"
     CDS             10376..10936
                     /gene="cobU"
                     /locus_tag="KNP54_002444"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBF0893324.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            10946..11719
                     /gene="cobS"
                     /locus_tag="KNP54_002445"
     CDS             10946..11719
                     /gene="cobS"
                     /locus_tag="KNP54_002445"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBF0893325.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            11739..12353
                     /locus_tag="KNP54_002446"
     CDS             11739..12353
                     /locus_tag="KNP54_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBF0893326.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENNSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12420..12599
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12729..14228
                     /locus_tag="KNP54_002447"
     CDS             12729..14228
                     /locus_tag="KNP54_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBF0893327.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14267..15643
                     /locus_tag="KNP54_002448"
     CDS             14267..15643
                     /locus_tag="KNP54_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBF0893328.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            15644..16615
                     /locus_tag="KNP54_002449"
     CDS             15644..16615
                     /locus_tag="KNP54_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBF0893329.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            16647..17717
                     /locus_tag="KNP54_002450"
     CDS             16647..17717
                     /locus_tag="KNP54_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBF0893330.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17719..18606
                     /locus_tag="KNP54_002451"
     CDS             17719..18606
                     /locus_tag="KNP54_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBF0893331.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            18594..19226
                     /locus_tag="KNP54_002452"
     CDS             18594..19226
                     /locus_tag="KNP54_002452"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBF0893332.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19235..20461
                     /locus_tag="KNP54_002453"
     CDS             19235..20461
                     /locus_tag="KNP54_002453"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBF0893333.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDNLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20458..21066
                     /locus_tag="KNP54_002454"
     CDS             20458..21066
                     /locus_tag="KNP54_002454"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBF0893334.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            21056..21631
                     /locus_tag="KNP54_002455"
     CDS             21056..21631
                     /locus_tag="KNP54_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBF0893335.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21624..22376
                     /locus_tag="KNP54_002456"
     CDS             21624..22376
                     /locus_tag="KNP54_002456"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBF0893336.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22360..23481
                     /gene="cbiG"
                     /locus_tag="KNP54_002457"
     CDS             22360..23481
                     /gene="cbiG"
                     /locus_tag="KNP54_002457"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBF0893337.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTQKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            23478..24203
                     /gene="cobJ"
                     /locus_tag="KNP54_002458"
     CDS             23478..24203
                     /gene="cobJ"
                     /locus_tag="KNP54_002458"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBF0893338.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24200..24952
                     /gene="cobK"
                     /locus_tag="KNP54_002459"
     CDS             24200..24952
                     /gene="cobK"
                     /locus_tag="KNP54_002459"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBF0893339.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            24971..26449
                     /locus_tag="KNP54_002460"
     CDS             24971..26449
                     /locus_tag="KNP54_002460"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBF0893340.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            26479..27384
                     /gene="hemC"
                     /locus_tag="KNP54_002461"
     CDS             26479..27384
                     /gene="hemC"
                     /locus_tag="KNP54_002461"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBF0893341.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27374..28873
                     /gene="cobA"
                     /locus_tag="KNP54_002462"
     CDS             27374..28873
                     /gene="cobA"
                     /locus_tag="KNP54_002462"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBF0893342.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            28890..29855
                     /gene="hemB"
                     /locus_tag="KNP54_002463"
     CDS             28890..29855
                     /gene="hemB"
                     /locus_tag="KNP54_002463"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBF0893343.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30008..30586
                     /locus_tag="KNP54_002464"
     CDS             30008..30586
                     /locus_tag="KNP54_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBF0893344.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        12420 a         3066 c         5673 g         9517 t
ORIGIN      
        1 tataaaattc ttaaataaaa agaaaaggtt gtttttataa aaaatatttt ttataccact
       61 ttaaaaaaca caataataac actgagggag gtggggatat gagagaacgc attattcttg
      121 aaacattaaa aaatagtagt ggttatctaa acatagatta ttttgcagat aagttggggg
      181 tatctactcg aactatcaga aatgaaataa aaaagataga aactataaaa gaatgtaatg
      241 gttttaaatt agaatataag tctaaattag gatatattct aaatattaaa gaccaagata
      301 aattcgagca ttatctaaga aacttaccct cagatttagt tgaaaatcca gaacaacggt
      361 tggagtctat aatagtagag cttttagtaa atgaaggtta taaaactata gaacagttaa
      421 gtaaaaaatt tctagtaagt tcatcccaaa taaaaaatga tttaaaaaag atagatgaaa
      481 agataaagga tacagaatta aaactagagc gaaaggctca ttatggaatt aaaatagaag
      541 gttctataaa agaaattcaa agtatattgg tggatagtta ttttagaggg aatagaaata
      601 taacagagta caggaataag tttatagata atttaaaatt agctaatatt agaagtacaa
      661 taaaaaatgt acttaatgaa catgatttag aagcaaattt aacagaactt gaggaaatat
      721 tagcacaaat tattatattg tatataagag ttagtatgag agtagtggga aatgctagcg
      781 atttaaaatt atatacagaa gatttaatta tagataaatt attagataaa atttttagag
      841 ataaaaaata taaccttaat tatgatgaaa agtattattt aaaggagctt ataaaactaa
      901 agactaaaga taagaaagcc actataaaga atattgataa gaataaactt caagatatta
      961 tgttcgaatt ttttagagag atagataaaa aatataactc taatttttta gaagataaag
     1021 agttttttaa cttattttac ttacatattg catgtttaat agaacgtata aagaagaacc
     1081 acaagataat aaatcctttt tcagttaaaa taagtcaaca gtatccaact gtttttaatt
     1141 tatctattca attttcaaaa atcatagaaa atgagtatca tataaaaata agtcaagatg
     1201 aaatagggtt tatagctact cacattgctg ttccttttga aaagagagaa gaagctaatt
     1261 ttaataaaaa atataaaata gcaataatat gctcttctgg tggaggtagt gcatttttga
     1321 taaatttaag acttaaagaa atttttccaa atgctgagat aagaaatttt tcattactag
     1381 aagaaaaagc tgtaatagaa tttgcaccag atttgatttt ttcaataaca aatcttttat
     1441 ttgaaataaa tgctccagtt atacttataa atgaaatttt agacgaattg gattatttag
     1501 atattaaaga aagtgttaga tttgcagacc atataggaaa tatatcaagc ccaaaacaat
     1561 atatattagg tctatttgat aagaatcact ttaggtgtat aaaagataaa gctaagtata
     1621 aggatatcct tgatagtatg tcaaaatgta tagttgacga gggagcttgt tctccaacct
     1681 atcccaaaga tgtatgggaa agagaaagtt atttgagtac tatttataca aatggggtgg
     1741 ctatacctca tccaatcgag atgacaggaa acaaaaatat aatatcagta gctttgatac
     1801 aaactgatat tatttatgaa aatagggtgc ctaaaattat tttcatgatt tcattaataa
     1861 agggaaattt agaacttcat aagcaaatat ctaaatattt aagtaagatt atggcaaata
     1921 aggatatggt agacatgcta aataagtcac aatcttatga agagtttatg tataagttaa
     1981 aaatctatct gggaggttag acatgaatat agagtttttt aagaggttgt cagaagcaga
     2041 tggtatagca tctaatgaag aagaggttag acatgtttta ttggaagaac taaaagctta
     2101 tagtgataaa attatctgtg atgggctagg gagtatcatc ttttctaaaa taaaagatga
     2161 gagtgcacca aacgtaatga tttgtgctca tatggatgaa gttggattta tggtgagaag
     2221 tatagacaaa cttggtatga ttcacttaat aacaatagga ggagtaaaac ctcttgcaca
     2281 gtttgtacaa aaagttagaa ttacaacaaa agaagggaag aaaatccccg ctgtcataaa
     2341 tgctacatat aataatggta aggctgaaaa tatatatgca gatattggag catatacaga
     2401 agaagatgta tataacctag ggattaatgt tggggatatg gtaacatata caacaagctt
     2461 tgaggaattt actttaccag accgattagt gggaaaggct tttgatgata ggataggatg
     2521 ttttgtgatg ggagaagttt taaaagaact taggaaagaa aatctaaatt gtaatattca
     2581 ctttgcggct acaagtagtg aagaggttgg aataagggga gcaaagacat caacacagtt
     2641 aataaatcca gatatagtat ttgtaataga tgtagcatgt gctaaaaatg agtttgtgag
     2701 agactataca aataagaaac aaattgataa aggtgtaatg ctaatgcata gagataggac
     2761 tctagtccct agtagaaaaa tgatagatta tgtaatggaa attgctgata aaaataatat
     2821 accacttcaa catgatatgt ttgaatcagg tgggactgat ggaggagaag cacatctcgt
     2881 aaatgaaggg aaaccttgtg tagtaacttg tgtaccagtt agatatggtc attgtgcatt
     2941 ttcaatagta agtaataaag atttggagaa cattataaga ttgtatacac agttaatttt
     3001 aaattttgat gaagaacaat ataaacatat aagaaatttt atctaaagga gaataagaaa
     3061 atgtcaacag aagtacaaat aatggaactt atatcaactg caggagagag taaatcgaaa
     3121 gcttttgagg ctttaaaaaa agtgaagtca aaagatttta aaggagcaaa attgttaata
     3181 gaggaggctc gtaaaataga tattgaagct cacaggatac aaacagaatt aataactcaa
     3241 gatttaaatg aagatgttga aagtccagca atgagtcttt taatggtaca tgctcaagac
     3301 cactatatga cttctcagct agcaaaagac ttgatagagg ctttgatata ttgtcttgat
     3361 aagtaattgt aatatagaaa tagattattt atgtaaaaat tcttttaaaa gtttagatgc
     3421 ttttaagaga taataaaaat acaaacttta ggaggaatta ttatgaaaat attattatgt
     3481 tgtgcaggtg gattttctac taatatgtta atgcaaaata tgaaaaaggt ggtaaaagag
     3541 agtgctaaac tcaatgaaaa agattttgag tttacagcta taccagcaga ttcaatagaa
     3601 agtgaagttg atgattggga tatagtactt ataggtcctc aaatagctca caaaatagac
     3661 ttcttaaaag gaatattaga gccaaaaaat aagccttttg cagtaataga taaagatgta
     3721 tatggaaaaa tggatggagc tacagttatg aagttggcat taataactta taagaaacat
     3781 caattagctc aaggataata aaaataatga gggaaaaggg agattagata tgttttcaaa
     3841 atttgaagca tttatgaata gagtatttat gcctttagct cataaggttg acaatcaacg
     3901 tcaccttggt tctataaagg ctggtatggt tgctatgaca ccattcacaa tattaggaag
     3961 tatatttgca atacttccag cacttccaaa tatgcttgga gaaaataatc caataagcaa
     4021 attcatactt agcaattcag caatattgga tttaccagta agtctttcca taggtttaat
     4081 aggattatat gcttgtatgt gtattgcttt taatctgggg aactactata aattatatat
     4141 accaggttgt gttgcactat caactttttc ttttttattc ctagtagcct catttacacc
     4201 agatggagct ttagaaatag gaaatttagg agctaaaggg ctatttacag gtatgatagc
     4261 agggcttggt tctgtggagt tatataattt ttgtaataag aagaatatca caataaaaat
     4321 gccagaaaat gtacctgatt ttgtatctag gtcttttgaa ttaataccta ctactataat
     4381 agtttgtgga acttttatag ttgctcgttt tatttcatta aaagtatttg gagaattacc
     4441 tccacagata cttactcaat ttttatctcc attagtagga agtatggata acccatggtc
     4501 agttcttgca cttaactttg ctatatgtac tatattcttt tttggaatac attcatcagt
     4561 atttagtcct ataactagac ctataatgat tacatttata gctgaaaaca tagcagctat
     4621 gcaggctgga gaaacaatac ctcatttctt tacagcagga gcttcaagtg cattctttgg
     4681 atttacagga tgtggaatta gtataggttg tgtaattgca tgtatgttat caaaaaatgc
     4741 ttcctataag aagattggac gtgtatcatt attccctgca ttatttggga taaatgaacc
     4801 aatattattt ggagcaccga taatattaaa tccaataatg tttataccac atgtatttgg
     4861 tggagctata ataggtacac taccaatgtt ttttatgcac tggggatggt tagcaaagcc
     4921 agtatttgac cctccatatg taggggtatt cttagaagga tttttaacta atggagattg
     4981 gcattctata ttagcaaatg cattgcaatt agtattagca gttttattat attggccatt
     5041 ctttaaaata atggaacgtc aacaaaataa taaaaaacaa aaagaagaaa ctaagaatat
     5101 attctctaaa gaagaagaag gcttattgga tgatttagga ttggatttct aatattttgt
     5161 tatgaataat acaatggaga gattagtatc cttaatctat aaaagaggtg ttgacgctct
     5221 tttgattaaa gcaaaaaata ctaaaagata tataggagct ttatcaggta gtggtgtata
     5281 tgtgcttgtt actaaggata aaaattatca aattctagat ggcagatata ttgatgaagc
     5341 agataaaaaa acgactggtt tcataaaaag gattgtatct caaggttctt atataccaac
     5401 tataattgag ttattaaaag aattaaatat aaaaaagtta gcaatagaaa accaagctat
     5461 gagtatacaa gagtatcttt cactaaaaaa tgaaggtttt gaaatcaatt taataacaaa
     5521 tgaattatgg aagctaaggg ctataaaatc taaagaagaa attaaactta ttaaaaaggc
     5581 ttgtgagatt acagatgaag tatttgatga ggttatttct gaaattaaaa aagatatgac
     5641 tgagctagaa gtatcagctc taattcagta tcatgcatta aaaaaaggtg caagtggaat
     5701 gtcttttgaa acaatagtgg tatcaggaga aagaggtgca atgccacatg gaagacctac
     5761 aaacaaaaaa ttgaaagtga atgaagctat aacaatagat tttggtgttg tttatcaagg
     5821 gtatcaatca gacatgactc gtacaatatc tataggcaaa cctcctaaaa ttattaaaga
     5881 gatatatgat gtagtattgg aagcacaatt atctgcaata gagtcaataa aggaaggaac
     5941 tagggcaagt gatgttgaca aagtggctag aaaaattata gataaacatg gatttggcga
     6001 atattttaat catggactgg gtcatggtat aggtcttgga gatggtgaag ttcccacttt
     6061 aaatccaaat agtgaagata tattagtgga aggaatggta atgtcttgtg agccaggtat
     6121 ttatattcca aatgtagggg gagttagaat agaagatgat attgttataa tagatggaaa
     6181 aggtgttcca ctcaataaga catccaaaga gtttataata ttaggagagt aaaattatga
     6241 aatataattt taataaagta ttaaatcgta aagaaggaaa ttgtagaaaa tggagcaacc
     6301 atgtgattaa agaaaaattt ggcttaaatg aagatgcaat tcctatggat ttagctgata
     6361 tcgattttga gtgtgctcct gctataaaag aatctatctt aaaaagagca tcagtaggag
     6421 attatagtta tacttttata ggagatgact tctatgatgc tattataaat tggaataaaa
     6481 gaagatttga tgtatatata gaaaaggatt ggataaaatt aacttttggt actgtttcaa
     6541 cccttcatta tatagtccaa gcatatacta aagaaggaga gggtgtattg ataaatacac
     6601 ctgcttatga cccttttgca gaggctgtag taaataataa tagaaagttg tgttgtagct
     6661 cattaaaatt agataacaat agatattatt tagatttaga ggatatggaa aatcaaatga
     6721 aatacgagaa tataagattg cttatattct gtagtccaca aaatccatca ggtcgtatat
     6781 ggacaaaaga agaactatat caagtgtcag agttatgttt aaagtataat gtaattttgg
     6841 taagtgatga aattcataga gatataatat ttaaagatta tagatttgta tctttgtgga
     6901 atgctcatcc agaaatttat aaaaatagta taatctgtgt atctcctaat aaaggcttca
     6961 acttaggtgg attaaaaaca tcatatgtat taataagaga tgtaaaaatt agggagactt
     7021 tattagaaag gctaaaaagt aattcaataa cttctccaaa tgtatttgca ataccagcaa
     7081 tagttgcagc atataatgaa agcgaagaat ggctagatgc tatgactagt tatgtagagg
     7141 agaattttga aatagtttat gatttctttg aaactaatat accaaaagct aaagtgatga
     7201 agtcagactc ttctttttta gcctggatag atgtaagaga agtatttaga aatgaagaag
     7261 aatctaaaga attttttaga catgcaaact taactatggt agttggaagt tattttgtga
     7321 aagatggaga tggatttatt cgtattaatg tggggtgtcc tagagaaaca ttaaatgagg
     7381 ctctaaatag aatcaaaaaa acgtatataa gtatgtattg ttaaatcata aaaaaagtat
     7441 ctatggttta tataaaaaca cattatttag ttatcaaata ttactggaat tttgtattcc
     7501 agtaatattt tttgattaag gaatattatt gaggaatatt aaataatatt atttcatacc
     7561 cttatattaa cttatataaa aatattttat tattttggga acgggttagc taacctttat
     7621 ctagtgtata tttatattgt aagaagcagt aaaaactttt cctttactaa gtttattaat
     7681 aaacttctta tctttataaa ttttgttaga atttatacta tcagcaagac cataccaagg
     7741 ttctatacat aaaaaaggag cagtagaatt agtttcacta taataaggag tccaaatacc
     7801 aactagaggg aaatcttcca tagatatagt tacatattta ctaccatcat tattacatat
     7861 agacacttca tctatgttgg tgtatatcaa agcatcattc ttgaatactt ctggatttaa
     7921 ctgtaagttt tttaattttc caataggtat tatatcatct gtaaaagaac catttaaatt
     7981 gattttttct acatcatttt tacttttaaa ctcaaggtag tgtttagaaa aatcattttg
     8041 ttcgtaaaaa ggaaggttga atgcaggatg tccacctata gaaaagaata tatctttaga
     8101 atcagtattt tttacaatcc attctacctc aatactatta tcatttaatg tatagtttat
     8161 gattagctca aaagaatatg gatacttctt taaagtagat tcattatctg ttaatttata
     8221 agttacaaat gtatctcctt tatctacaat ctcaaagtcc atatctctag caaacccatg
     8281 ttgagtcatg ctatataaat tttcttctat tattgtttca ttatcaaaaa gtttacctac
     8341 tatagggaac aatataggtg attgtctacc ccaatatttt ttattaccat cccaaagaat
     8401 gtttttgtcg tattttttag aaaatatttt agttagttca gcaccaaaac tgcttgattc
     8461 gataattaaa ttttcatttt gtaatatatt catttaaaat ctcctttatt atattttatg
     8521 agtatattat actataaagt ataaagatta ttaaatttta tttgatatta tatttgaaag
     8581 gtagatttta gtatattttg aaaattttgt tttgaaaatt tgggattatt taagaaattt
     8641 tgtattataa atagaaggaa atagataaat tgtatagaat aaaatatatt aagataagtt
     8701 aataatgtta aatgggaagt gagtttatgg aaaaaccaaa tacaaaagtt gttaactttc
     8761 aagagtataa agacagaaaa aaccaaagag aagtaaatag agacgaactt ttaaagctta
     8821 taaaaaaaat tgtgacttca aaatagggag ttgttaaact ccctatttta atgggtttca
     8881 taataattaa gacattctaa gtccatctat ataatctttg aattgtgaga aatctgattc
     8941 actacttaat tctatggttt ctgaaccttc cgtataaaaa ttcttaagat agatagtata
     9001 attattatca acacaatcat gataaataca tctatatcca tcttcataca aactttttaa
     9061 cttagaaaaa tcatccacaa tatcatctcc ttaaagttct tttaaatata tttttacaaa
     9121 aagcatctaa ttgtatgcaa attgacaatg taaaataaag gaaatgaaca taaaatgtag
     9181 aataattttt atatgtatgt aaaaataaaa agaaaaagtt gaaattttta gaaaataaga
     9241 gtatttttta tctaaaaaga gagtttaaaa aataaaaaaa tgttgggagg ataaaaaatg
     9301 agtttattag aaagtatatc aaaaaacata tattccctag ataactcttc tattgaaaaa
     9361 acaaagcaga gattggatag gcttatacat ccaactggaa gcttaggaaa gatagaagat
     9421 atttgcatgc aattagcagg aatatttggc aatgaaaatt ttgacacaag taaaaaggtt
     9481 ataattgctt ttgcgggaga ccatggtgta tatgaagaag gcgtagcacc tgaccctcaa
     9541 aatataacaa aattacagtt tccaaatttt tcgaaaggtc tatgcggagt tggagtaata
     9601 agtaaatttg taggggcaga tgttgtagct gtagatgtag gaataaactg tgatgaaaaa
     9661 ctggatgggg tattagacta caagataaga aaagggacat caaatatggc aaaaggtcca
     9721 gctatgagta aacaagaagc aattagatgt ttagagatag gtattgaaat agcagagcag
     9781 tgtatagaaa aagattataa ggttattggt attggggaga tgggtatagc aaatactact
     9841 ccaagtacag caataatatc tgtaatttca gggtgtgacc cgttagaagt tactggtata
     9901 ggtgcaggtc ttaagaaaga aagactaaag cataaggctg aagtaattag aaaggctatt
     9961 gaaattaata atccaaatcc aactgatgga gtagatattt tatctaaagt aggagggttt
    10021 gaaataggct caatggcagg tgttatatta ggttgtagtg ctaataggat tccagtagta
    10081 attgatgggt ttatttctta tgcagcagca ttaattgcat ataagataaa tccaaaaact
    10141 agagaatata tgatagcatc tcatttatca gcagaatcag gaactaaaag agcattagac
    10201 atattaaaat tagaccctct attaaatatg gatatgagat taggtgaggg aagtggagct
    10261 gctttagcat ttgatataat agaagcttca aactatactt ataaaaatat ggcaactttt
    10321 gatgaaattg acatgggaag ataaatataa aaatttaata tgtaggagtg ttttgatgag
    10381 taaaattatt ctagtaacag gaggagctag gtcagggaag agtaactttg cagaaaaact
    10441 atgttttgac agaaataata atacagctta tatagcaacc tctattccat ttgatgatga
    10501 aatgaaagat agagtaaaaa aacatcaaga gaatagacct agaaactgga atacttatga
    10561 aatatatgaa gatatatatt ccataattaa ggagatatat aaagaacatg aaactgttat
    10621 actagattgt gtaacattat tagtaaataa tctaatgttt gaacacaatc taaatataga
    10681 agaatctagt caagaagaaa taaacaaatt agaacaatac ataaaagaac aagttgtcaa
    10741 acttattgaa gaaatagaaa aaacaaatct atactttgta tttgtaacga atgagttagg
    10801 tatgggaatt gttcctggga ataaacttag tagaatttat gctgatattg taggtcgtat
    10861 aaatcaatat atagcttcga aaagtaatga agtttatttt gtagttagtg gcatagctat
    10921 gaagataaag gagtagtatg caattatgaa aagatttatt ttaatactac agtttttgac
    10981 aaggatacct ataaaattaa atgtaggatt tgatgatgaa ttttataagt caatagtata
    11041 ttttccactt gtaggttttg tcataggtat attatcctat ttaataggat ggatttctat
    11101 gcttttattt gaaccattta tagcttctat aataataact ctagctggtg tcttaattac
    11161 tggaggactt catatagatg gattaggaga tacatttgat gcaatatata gttataggga
    11221 taaagaaaag atgcttgaaa taatgaaaga ttcaagatta ggtacaaatt cacttctagc
    11281 aattatgttt gtacttttat taaaggttgg attcgtttac gatataataa gtaataattc
    11341 attgtgggtt ataattttta tgccaatgat tgcaaggtta ggagtaatgt tattgacata
    11401 taaaactgtg acaccaagag aaaaaggaat gggaaattta tttataggaa aattaactac
    11461 aagtatgtta ataactgcta taatatacac attattgata gttgctctta ttactaaatt
    11521 tatattttta ttacctaata tagtgttgat taaagtatta ggttcgatta tagtggtttt
    11581 tgtatttata atattattca aaaaacatat ttataaaaaa attgacggag taacaggaga
    11641 tatattaggc tgtggaatag aactttcaga gcttgtatat ttaatttaca tatatttgtt
    11701 aatttttatg tttttttaaa gtaaaaagtg gtgataatat gataagatta atattaataa
    11761 gacatgcact gacaaatgat aataaaaaag gaagattatc aggccatata aatagttgta
    11821 ttagtgaaga gggcaaacta caaataaata aaattaccag atatctgagt aatgaaaaca
    11881 tagataaggt ttatacaaca ccatctacac gtactaaaga tacagtagaa aaaatatcaa
    11941 aattgaaatt attagaaata gaagaaaaag aagctttaag agaaattagt tttggagact
    12001 ttgaaggaag aacttttgaa gaaattaaaa tcaaatatcc aaatgagttt gaaaaaatga
    12061 taaaagaagg taacaactat agatatccaa atggagaaag tttgatagac tcttataaaa
    12121 gagtggcaaa agaaattgat aatataattt tagaaaataa tagtaattta gatacaaaga
    12181 caatacttat atgttctcat gcaggaacaa taagaaatat aataacacat ttgatttctg
    12241 gtagttataa gtatcactgg aactttaaaa ttgataatgc atctattaca gttttagaaa
    12301 ttgatggtgg atttgctgta atagataaaa tgaattttac agacttcata taatttaatc
    12361 aaaaccaaac attacaatct gtgtttgtaa tatatctgta aaattagcaa tgaaaataga
    12421 atattagatt aaaattaggt tcttaattag atgttaaaag ggaaaaaggt tagatgcctt
    12481 tgcagccccc gctactgtga aaccaacgaa actataaata ccactgtcag tttgatggga
    12541 aggttataga agtaggatga agttaagcca ggatacctgc ctaatttaat ttaaaacaag
    12601 aggtcttcgg ggtgaaagat ttttaattaa tatatataaa agtcctatct ttagaagtat
    12661 taggactttt tttaatttgt tttttagtaa attttaacaa ggagggatgg aaagtgggga
    12721 aaaaaataat gctacaagga acagcttcaa atgtaggtaa aagtgtctta gtagcaggtt
    12781 tgtgtagaat atttaagcaa gatggttata ctgttgctcc ttttaagtca caaaatatgg
    12841 ctttaaattc ttttataact aaagaaggat tagaaatggg aagagcacaa gtatttcaag
    12901 cagaggctgc gaaaatagag ccaatagctg atatgaatcc agttttatta aaaccttctg
    12961 gaaataataa aagtcaagtt attgtaagag gtaaagttgt aggagaaatg ccttcttcta
    13021 agtatcatga ttataaattg gagttagtag atgtgttgaa ggaaacattt aatagcttaa
    13081 attcaaggta tgatattgta gttatggaag gggcaggaag taatgcagag ataaacttaa
    13141 aagatagaga tatctctaat atgggtatgg cagaaatagc tgatgcacct gtaataatag
    13201 tcggagatat tgatagagga ggcgtatttg cctcattagc aggaacaatg cttttattaa
    13261 atgaagatga gaaaagaaga gtaaaaggtg taataatcaa taaattcaga ggaaaaaaag
    13321 agcttttaca agatggtgta aagatgctag aagacatcat aaaagtacct gttataggag
    13381 tagtacctta tacagatata aaaatagaag atgaagacag tgtaactacg agatttaaga
    13441 aaaaaatgaa taaaagtgat atacacatag aaataattag aaccccacat atgtcaaatt
    13501 ttacagattt taatatattt gagacacaag aagatgtaag tataagatat gtagactatg
    13561 gagaatcttt aggaaatcca gatatattaa taatacctgg aactaaaagt actatagacg
    13621 atttaacata tataagaaaa agtggtcttg aatcgcaaat caaaaattta catagtcaag
    13681 gtaaattgat atttgggata tgtggtggat accaaatgtt aggtaaaaaa ttaaaagacc
    13741 cttatcatgt tgaaagtgaa attgaagaag ttgatggaat aggtctttta gatacagaaa
    13801 caacgtttga gaaagaaaag actacaacac aagtagaagc tactattgtt gaatgtatca
    13861 gtgaatacat gaataacctt aagggaaaaa aagtaaaagg ttatgaaatt catatgggaa
    13921 ttacaaagcg aggtaatgat gtaagaagtt tagatttaat aactaaaaaa cttgataaag
    13981 aagtgaatta tactgaggga agtgtaaata aagaggggaa tgtaattggg acttatcttc
    14041 atggaatatt tgatgaaata agctttacaa gagcaatttt aaacaatata agaaagaaaa
    14101 aaggtttagg agaattagaa agcaaagtaa actcttttaa tgaatttaag gataaagagt
    14161 atgataagtt ggctgatttt ttaagagaac atttagatat agagaaaata tatgagatta
    14221 tgaaataatg atgaccttta tttataattt aggtaggagg tgtattatga aaaaaatttt
    14281 aattgcgggt actaatagtg gagtaggtaa aacaacaata tcattaggaa taatgcaagc
    14341 tttggttaag agaaatatga aagtacagcc atataaagta gggccagact atatagaccc
    14401 ttcatatcac acttttataa ctggaagaca ttctagaaat ttagattctt atatgttaga
    14461 tgatgaaaaa ataaagtata tagtaaataa gtcctcaaaa gatgcagata tttcagtaat
    14521 agaaggtgtt atgggcttat atgatggctt tggaatagat ttagataatt gtacaagttc
    14581 acatacttca aaggtattaa agtcacctgt tatattagtt ataaatggta aatctatggc
    14641 agcatctagt gctgctatgg tacttggata taaggaacta gataaagatg taaatataaa
    14701 gggtgttata gtaaataatg taaagactaa tagccattat caaataatta agagttctat
    14761 agaaaaatat tgtaatgttg aagtattggg gtattttcct ccaaataaca aattctcttt
    14821 ggaatctcga catctaggat tagttcctag tgtagaaatg aaatcactaa gggaaaaatt
    14881 ttatacctta gcagatgaaa ttgaacacta tatagatatt gacagaataa ttgaaatatc
    14941 agaaagtgat gaatttgaga gtgattttga ttttcaaact ttgatagaaa ataataaaat
    15001 aaaagaacat gttaataata aatcaatagc tatagcatat gataaagcat tcaattttta
    15061 ttatagagaa aatatagagc ttttagagga acttggttta gaaataaact attttagccc
    15121 tcttgaagat gtatcagtgc caaatgcaga ttatatttat attggaggag gttttccaga
    15181 aatatttgga aaagaattag aagcaaatga gtcaatgaga acttccatat tagaagcaca
    15241 taacaataat atacctattt atgcagaatg tggaggactg atgtacctag gtgagaaact
    15301 attgaatcaa gaagaacaag aatttaatat ggttggaata tttagtggaa ttagtaagat
    15361 gacatcttct ttaaagagat ttgggtactg tattggtgta gccaaggaaa atactctttt
    15421 atctaaaaaa ggggaatcca ttaaagggca tgagtttcat cattcaatat ttgaaagtga
    15481 tgaaaaatgt gtatattcaa tgagaaaaga aagagatgga aatatagtag aagagtggga
    15541 tggtggttat agtaaaggaa acactttggc tacatatctt catactcatt tttataataa
    15601 cttaaattgt atagaaaatt ttttgaaaaa aggaaatgaa taaatgagta ttttatctat
    15661 ttatatagga tatgtgacag acttaattgt aggagaccca tattcttttc ctcatccagt
    15721 gagatttatt ggtaaactta taaattttac tcaaggtata ataagaaagg tctctaaaaa
    15781 tgataggcag ttaaaatttg ggggatttat attatggttt ataaccgttg gaataacata
    15841 tttaacaact tatgctatag tgaagttatt tagttttaat atattattga gtattgtagt
    15901 gaatagtttt ataatttata caacactagc cacaaaatgt ttaaaagacg aagcattaaa
    15961 aatttataat gtattaaaaa ctgaagatat agaaaaatct aggattcagc tatcttatat
    16021 agtaggtagg gatactacta atttaagtga acctgaaata ataagagcaa ctgtagaaac
    16081 tgttgcagaa aatactgtag atggtataat tgcgcctatg ttttatgcat ttattggagg
    16141 agcaccactt gctatggcct ataaagctat caatacattg gactcaacag ttggatataa
    16201 aaataaaaag tataaagata ttggttttgc atctgctaag attgatgata tagccaatta
    16261 tataccagct agaatatctg tcattcttat gacaattgga agtttctttt taaattataa
    16321 ctataggaac tgttttaaaa tctctattag agatagaaag aatcataaaa gtccaaattg
    16381 tgctttttca gaaggtgcag tatctggtgc tctaggaata caactaggag gtaccaacgt
    16441 ttattttggg gaaaaagtat ataagccaac aataggggat aagcttaggg agatagataa
    16501 agaagatata attaaaacta ataaaattat gtatgcatct tcatttgtat ctatgttggt
    16561 atttacacta atatatgtgt tatgtaggat gattttaatt aacttaatta tataaattat
    16621 tgtttgttaa cttaaggggg acatagatga aggatttagg gcatggtgcc aatgtagatg
    16681 aaatggcaag attatatggg aaaaacccaa aagaaataat tgattttagt tcaaacataa
    16741 atccaaatgt attaccaaat ttagagagat acattttaaa aggattagaa gagtgtagga
    16801 attatccaga tataaattat acaaacttga gagaaaatat atcaaaatat atagatataa
    16861 atccagactt tataatacct ggcaatggtg caacagaagt gatttatttg cttatgaaga
    16921 gtattaaaaa aaaattggct ataataaatc cgactttttc agagtataga agaagtgctg
    16981 agttaaataa tttagatatt atagatttag agttagattt agaaaataac tttaaactta
    17041 atatagatat aataaaagaa aatataaaaa gatttgatag tttatttata tgtaatccta
    17101 ataatccgag tggtaatgtc caagatttaa aggaacttgt tcatttacta gataaacata
    17161 ataaggtact aataattgat gaaactttca tggaatttgt tgaagatgaa agtaaatata
    17221 gtttggttaa atatatagaa tcaaataaaa atatatttat aattaaagct gtgactaagt
    17281 tttttggtat gcctggttta aggctaggat atggtcttac aagcaacact gaaattatga
    17341 acaaaattta tgaacacaaa gagccatgga ctatcaattc ttttgcagat atactatcca
    17401 attttatttt tgaagataaa gagtatatta aaaatagtaa agaatattac atagaagaaa
    17461 gaaaatatat gttacaagag ttgagaaaca taagaaatat aaaggtctat gatacagatg
    17521 ctaattttat cttgataaga atatataaaa aaacaactaa agaattgaaa aaagatttgt
    17581 ttaagcaagg aaacatatta gttagagatg catctaattt tataggatta gatgatagct
    17641 ttataagagt ggctataaaa tctcatgaag ataacaaaat tcttatagaa aatatgaaaa
    17701 atttattggg tgattaaaat gaaatcttat ggaatatgcc cagcatcttg tggagaattt
    17761 gtacaaggta taattgatga tgaagaatat ttatgttcat atgcaataga tatgtattct
    17821 aaagtgtata ttgaagaaaa attagtagat ataaatttag ggagatataa gtcaaggtta
    17881 gcaattgaaa aggtatttga aaaatttaat ctacctaaaa aatatactaa aaatatttct
    17941 ttaaatataa atagtaaaat acctgttgga aaaggaatgg caagttcaac tgctgatata
    18001 ggagctacta taaaggcaac attatcattg atagataaag atttaagtag cgaggagatt
    18061 tctaaattag cagcagaaat agaaccaaca gattctatat ttatagataa aaatagtata
    18121 tttaatcctc taaatggaac tgttataaaa tacctaggaa atctgaccaa tgcgaaagtt
    18181 gtaatacttg aaccaaacaa agtactagat actatgaaaa ttagattgag gcaagattat
    18241 aataaattaa aagtagagaa taaagaagta ataaaaaaat catttgctct tttagaagaa
    18301 ggattgaaaa aaaataattt atctctagtt ggagaggctt gtactttgag tagcttagca
    18361 aatgagaata tagaaaaaaa agagtattta aatgaaataa taaaaatatc aaaaaaatat
    18421 ggagcatatg gagtaaatat tgctcacagt ggaactgtag taggtatttt aattgataag
    18481 tttatgaatg ataaaaagat gatagatgcc ttatgtgaat ctaacataaa ttctgtctat
    18541 aataaaattt atacacaaaa cataattaat ggaggaatta agggggaaat agaatggaat
    18601 acataaagaa tcctatgaaa atagaagaaa aaagttttga attgatacaa gaaataatag
    18661 acgaaattag accagattat aaatttaaga ataatatcga agaaaaaata ataaaaagag
    18721 ctatacatac tactgctgat tttgattact tagatatatt aaaaatatca gaagaagcag
    18781 ttgatagtat aatagatgca ttaaaaaata atgcaagtat ttatactgat acaaatatgg
    18841 ctcttagtgg tataaataaa agaaagttag aatcattagg atgtaagtat aaatgtttag
    18901 tggcagatga tgaaactgta aaattagcta aagaaaaagg aattactcgt tctatggcag
    18961 cagtagaaat tgcagctaaa gaagaaggaa gaaaaatatt cgttttaggt aatgctccaa
    19021 cagctttata taaagttatg gagatgaaat cagaaggtag attagattta gatgcagtta
    19081 taggagttcc tgtaggtttt gtaggagcac aagaatcaaa agatgaagtt gaaaaaacag
    19141 atataccata tataatttct aaaggtagaa aaggtggcag taatttagca gcagcaatag
    19201 taaatgctat attatatact atgtaggtac ctatatggaa gaatatgtat atatagatgg
    19261 aaaaaaatat agaagaggat atactacagg ttcatgtgca acaggtgcat ctaaggctgc
    19321 tgtatatatg ttgattacaa aaaatagaat caatactata aatatagata ctcctaaggg
    19381 gataccatta ctactaaaag ttgataatat aaatatttct gatacatttg tggaatgttc
    19441 cataaaaaaa gatggtggag atgatataga tgcaactcat accatggata tttatgcaag
    19501 agctgaaatt gtagctaaaa atgataagaa caaagggtat cttactctaa aggatataga
    19561 taatttaagc accaatagtg agtgtaaaag tgagctctat aagtttatta gggtttatgg
    19621 cggaactggt attggtgtgg ttacaaaaaa aggtcttagc gtggatgttg gtaaacctgc
    19681 tataaatccg actccactta aaatgataaa tcatgaaata agaaagctta taggagataa
    19741 ttttgaatct atacttggaa atgataaagt tttaaaaata acaatctttg ctccacaagg
    19801 agaaactgta gcaaaaaaaa catttaatcc aagattaggt atagttggag gaatatctat
    19861 aataggtaca actgggattg ttgaacctat gagtgatgag ggttggaaga agtctctatc
    19921 tatagaactt cagatgaaaa aagaacaagg cttagataaa ataatattgg ttccaggaaa
    19981 tcatggagaa cagtttataa gagaaaaatt aaacttagat attaagtatg tagttagggt
    20041 aagtaatttt ataggctata tgattaaaga agctcaaaga ataggatata agaaaatctt
    20101 aatggcaggt catataggta aatttataaa agtatctgct ggtattttta atactcatag
    20161 taaggtagca gatgctagaa gtgagatatt agtggcaaac ttagctttaa tgggagctag
    20221 atacgaattt ttaaataaaa taaatcaatg cgtaactact gaagaagctg tagagctaat
    20281 aaataatagt gaatatagag aagtatataa tatattaagt aataaatgta gggagagagt
    20341 aaagcaatac ttgaatgaag attcagatga tattgatgtg gaagtaatca tattttcaat
    20401 ggataagtct ttattaggta aatcggataa tacagatgat ttagtggagg tctttatatg
    20461 ataaacataa taggtctagg acctggtaac ttagactata taacaaaaaa aggtgaaaat
    20521 ttaatttcca cttctgatgt attaattggt ggtaaaagaa atttagagtc tataaaaaat
    20581 tttgaaggag aaaaaatagt tctggattct aatttaagag aaattataga gtacataaat
    20641 aacaataaag aaaagcaaat atcaataata gcatctgggg acccactaat atatgggata
    20701 ggtagatatc tatctaaaaa tattgataat aagatgttaa acatggtttc tgggattagt
    20761 tcattacagt acatattttc aaaaatatat gtagatatga atgatgtata tattacaagt
    20821 agtcatggta aagtaccaga ttttgattac atattatcac ataaaaaagt atgtatggtt
    20881 acagattcaa agataggacc aaaacaaata agtagagaaa taatagatag aaatctaaat
    20941 aaaattattg ttgtaggaga aaatctgtca tatgacaatg aaaaaataac aatagcaaaa
    21001 ccagaagaga taataagaat ggacaatttt gatatgaatg ttgtggtgat tttagatgag
    21061 gaatagtgaa tttataacag gtaaagttcc aattactaag gaagaggtta gagcaatatc
    21121 aataagtaag ttaaatttag taaatgctaa aaacctcata gacatagggg ctggtacagg
    21181 aagtgtaagt gttgaagctg catataatta tcctaattta aaggttatat ctatagagaa
    21241 aaatgatgat gctatagagc ttatagagaa aaataaaaaa aaattcaact tgaaaaatat
    21301 agaagtgata aaaggatatg ctccaattaa tctagggtta aatgttaaag ttgagtctat
    21361 ttttcttggg ggaacaggaa ataatctgga agaaataata gaatggtcta aaaaaaatct
    21421 cgttacagga ggaagacttg tagctaattt tataataata gatacattta atcaaacttt
    21481 aaaactgctt aaaaagcatg gatttaaaga aatagatgta tgtgttttga atgtttctaa
    21541 actagagaaa ctaggaaaag gtgaatattt taaaccacta aatcctatat atataatatc
    21601 ttgtgaaaaa ggggaaaatg atgatgaata aagtacattt tgtaggagca ggacctggag
    21661 ataaagagct gataacatta aaaggataca aattattaag taatgcagat gtagtgatat
    21721 atgcaggttc acttgttaat cctgaacttt tggaatactg taaagaagat tgccaaatac
    21781 ataatagtgc acatatggat ttacaagaga taatagatgt tatgagagaa ggtatagaaa
    21841 ataataaatc tgttgtaaga ctgcaaacag gtgatttttc tatatatggt tcaattagag
    21901 aacaagtgga agatttaaat aaattgaata tagattatga ctgtactcct ggagtaagtt
    21961 cttttttagg ggcagcatca tctttagggg ttgaatatac agttccagaa atttctcaaa
    22021 gtgtaattat aacaagaatg gaaggcagaa ctccggttcc agagaaagaa tcaatacaat
    22081 catatgctaa gcatcagaca tctatggtaa tatttttatc tgttcaagaa attgagaaag
    22141 ttgtgtctaa attactggaa ggtggatatc caaaagatac tcctatagca gttatataca
    22201 aagcaacttg ggcagatgaa aaaatagtta aaggaacttt aagtgatata gctgtaaaag
    22261 ttaaagaaaa caacataaat aagactgctt taataatggt tgggagattt ttaggagaag
    22321 agtataataa ttcaaagtta tatgataagg atttcaaaca tgaatataga gggtaatatt
    22381 gctataatct gtattacaga aaatggaaaa aaattagctc taaagataaa ttctctagta
    22441 aataactgtg ttatatatca agtaaaaaat aaaaaaagta atttagttgt tgaagaaaca
    22501 tgtgtgcata cagttcaaaa gaagttaagt gattttgtag gagaaatatt tagcaaattt
    22561 gattacatag tatttataat ggctacaggt atagttgtac gaagtatagc accatacata
    22621 ataagtaagt ttagtgaccc tgcaattttg gtaatggatg aaaaaggcaa aaacgtaata
    22681 agtttattga gtggtcatat tggaggggca aacagcttga cacagtacat aagtagtctt
    22741 attgatgcta atccagtaat aacaacagct actgatataa atcaaaaagc ttccttagat
    22801 atgatagcaa aaaaactaaa tgcacatatt gataatttta gagaaagtgt aaaagaagta
    22861 aattctatgc tagtgaataa taaatgtgtt ggattatatg ttgatgaagg atatcaagtt
    22921 gatactaggg gatttaaact tatagaaagt aaggatgagt taagagatag tttttcaaac
    22981 acatatatag aaaaattagt tgtagtaagc aataaaataa attgtattga agatattgag
    23041 aatttaaacc tagataataa atttgaacat tgctatagta cccaaaaaat aataaaggta
    23101 attccaagag atatagtgat aggaattggc tgtagaagaa acacagatag tgaactgatg
    23161 tataattcac ttgaagagtt tcttaataaa caaaatatag atattagagc aataaacaca
    23221 gttggaagta tagaactgaa aaaagacgaa aaagcaataa ttgaattatc aaaaatattg
    23281 aaggtgccat ttaaaacatt ttcagtagat gaaatatcta aggttgataa tctttttgat
    23341 aaatctgatt ttgttaaaaa aaatgtgggt gtgtattcag tagcagaacc tgtagcatat
    23401 cttttgagca aaggtaattt gttagttgaa aaacataaat ataaaggaat aactttttca
    23461 gtggggagaa taaaaatatg atatacgttg taggaattgg accaggaagt aaagatacaa
    23521 tgactttaga agcaataaaa gcaatagaag attctgaggc tattgttgga tataagactt
    23581 atataaaact aatagaagaa tttatacaag gtaaagaaat aatccaaaat ggtatgaggc
    23641 aagaagttga tagatgtaaa caagcagtgg aggaagcaaa aaaaggaaaa aaagtagcag
    23701 ttgtaagcag tggtgatgct ggaatatatg ggatggcagg tcttatttta gaattaatat
    23761 ctaaagaaga tgaagatata aaagtaaagg taattccagg cgttactgca agtattggtg
    23821 cagcagctat acttggagct cctattatgc atgatttctg tcatataagt ttgagtgatt
    23881 taatgactcc gtgggaagta attgaaaaaa gattgagatt ggctgctgaa gccgattttg
    23941 taatttgttt gtataatcca agaagtaagg gaagaagtga acatctaagc aaagcattca
    24001 aaataatggg tgagtttaaa ggtggagata cacctgttgg agtggtaaaa gatgtaggta
    24061 gagaaaaaga agaaaagttt gtatgtactt ttgaaaatat ggactttgaa aaagtcgata
    24121 tgactacaat ggttataata ggaaataagt ctacctatat taatggtgaa ttgatgataa
    24181 ctccaagagg ttatacagta tgattttaat tttaggagga acttcagata gtttatctat
    24241 atgtgataag ataaatgaac tgaaaaatca accatatatc ctttcagtta ctacagatta
    24301 tggaagggaa cttgcacaac aacatgcaga gaatgtaatt ttaggtaagc ttggaaaaga
    24361 agatatgcta aaatttataa aagataataa tatagtaaaa ataatagatg ccactcatcc
    24421 ttatgcagtt gaagtatcca aaactgctat tacttgtgca aaactattga atatagatta
    24481 tataaggttt gagagaaaat ctttaattga agaaatagat tatgataata aatttatagt
    24541 agatacaatt gaagaagcct gtgaaatagc aaataaaata gggacaaata tattcatagg
    24601 aacaggaagt aaaaatttga acagatttat agaggaaata agtgataaaa atttagttgt
    24661 tagagttctt ccaacgagtg aagtcatatt aagttgtgaa aaattaggtt taagtgcaga
    24721 taatatagta gctatgaaag gtccatttag ccagtatata aatgaagaaa catataaaca
    24781 ttacaatata gatttagtca taacaaaaga aagtggaata gctggtgggt tcttagagaa
    24841 ggtaaatgca tgtaaaactt tcaatatacc agtaataatt ataaaaagag aatcgattaa
    24901 ctacgaaaat gtatttaatg acataaataa aattaaagac atacttgtgt aatttttagg
    24961 aggagaatat atgaagaaag ccttattagt agtgagtttt ggtacaagct atcatgaaac
    25021 gagagaaaag acaatagata tatgtgaaga taaaataaaa aattcgttaa aaagccatga
    25081 tttttttaga gcttatacat caaatatgat aataaataaa ataaaaaaaa gggatggaat
    25141 agaaatagat aatccaatac aggctttaga taaaatatat gaacaaggat atgatgaagt
    25201 aataatccaa acacttcata ttatatgtgg cgaagaattt aacaaattaa aagaacaagt
    25261 agatggatat tcttctaaat tcaaaaagat tgtattagga agacctttgc ttacacatat
    25321 tgaagattat caggaagctg tagaggcaat taagcatcaa attcctcata tggaaagtaa
    25381 tgaagcagta gtatttatgg gacatggaac acttcatgaa tcacattcag cgtatccagc
    25441 attggaatac atgcttaggg ataatggaat aaatgcttat gttggtacag ttgaagggta
    25501 tccagaaata gaacatgtaa taagaagatt aaaagaagga aatataaaaa ctgtaaattt
    25561 gatgccattt atgttagttg caggagacca tgctataaat gatatggcag gagatgaaga
    25621 agattcttgg aaaacaatat tagaagaaaa tggatttaac gtaagagttc atttaaaagg
    25681 actaggagaa aattcttata tacaagataa atttgttcgt catgctgtaa aatgtgcaga
    25741 gaatgcgaag ttctatggta taggagcagg gccaggagat ggttctttac ttacgataaa
    25801 agcggttaat actttaaaga aactggatat tctatacact ccagaatcaa aaaagggtgg
    25861 agatagtcta gctttatcaa tagttagtga atatttacct gaatcagtgg aaataaagtc
    25921 taggcatttc ccaatgagtt ttgatgggaa tgaaaaaagt ttagcttggg acaatgtggc
    25981 acaagaaatt atatcagatg ttaatgatgg taaaaatgta ggatttgtta cattaggaga
    26041 ccctatgatt tatagtacat atgtatatat aatgaaaaga atattaggag aggtagaagt
    26101 cgaaactata ccaggaattt catcattttc caatatagca tctaatcaga attttccatt
    26161 agtcatggat aaagaagctt tagtggtaat tccttgtact atggaagatg ataagataga
    26221 gtatgctttg caaaattata attcaatagt attgatgaaa gtatataaaa attttaaaga
    26281 aataataaaa aaattagaaa agtatgattt aatagaacat gctattttag taagtaattc
    26341 ttcccaagaa agcgaaaatg tgtttacaga tttaaaagaa gcgcaccttg aagataagat
    26401 atcttatttt tctactatac tagtaaataa agataataaa ataaaatagg tgaaagcaat
    26461 atttaaagga gacttaatat gaatatagtg gttggaacta ggggtagtaa tctagcgctt
    26521 atacaaacag aatgggtaat aaatgaatta aaaaagaagt atccagaaat tagttttgag
    26581 attaaaatca taaagacaaa aggagattta attcaaaatg tttcactgga taaaataggt
    26641 gataaaggat tgtttgtcaa agaaatagag caacaattat tagatggaaa aatagacata
    26701 gcagtacata gtatgaaaga tatgccttct tatttagcag atggactaaa atttgctcat
    26761 acgcctaaga gagaagaccc aagagatgtt ctaatactta gagaaggata taaaaattta
    26821 gatgatttgc ctcatggagc agtaatagga acaggaagta aaagaaggaa gtttcaatta
    26881 ttgaaacaaa gacctgattt aaatatagta caagttagag gtaatgtgga aactaggata
    26941 cgaaaaataa aagatgaaaa catgcatggt attgtgttgg cagcatcagg aataattaga
    27001 gctaatttac aagataaaat aagttcttat ttacctgttg atgttgttat tccagcacct
    27061 gcccaaggag ctttagctat agaaattaga agcaatgata gtacgataga gggaatagta
    27121 aattcactga aggatgagaa tacagaaatc caaatattgg ctgaaagagg ttttttagat
    27181 ggtgtaaatg gaagttgtca tattccaatg gcagcttatt gtgaaataat ccaagataaa
    27241 atacatctta ctggcttata tggagattca gaaggaaaaa aagtagtaat caagtctata
    27301 gatggagata tttcttctcc tagagagtta ggtttaaagt tagctaaact tgtattgaag
    27361 gagtatgaga attatgaagg gtaaggttta cttagtaggg gcaggaccag gtgattataa
    27421 actcatgact ttaaaaggtt tagagtgtat aagaaaatcg gatgtaatag tatatgatag
    27481 attagcaaat agtagttatt taagagaagc taagcctgat tgtgaactta tatatgtagg
    27541 caaggcatca agtaatcata ttttgccaca agaagatata aatagaatta tagcagaaaa
    27601 agctaaagaa ggaaaaattg taactcgtct taaaggagga gacccttatg tatttggcag
    27661 agggggagaa gaagcagaga ctttagtaga tgaaggtata gaatttgaag tagttccagg
    27721 tataacttct gctataggag gtttatgtta tgcgggtatt cctataacac atagagacca
    27781 tgcttcgtca tttcatgtaa taacaggtca tttgaagggt gatgatagtg gagaattaaa
    27841 ctggaatgct cttgcaaata acaaaggtac tcttgtgttt ttgatgggaa tttcaaacct
    27901 agagaaaata agtgaaaact taatgaaaga aggaaaagat aaggatacac ctgttgctct
    27961 tataagttgg gcaactagat ataatcaaag agttgttaca tctacacttg aaaatgttta
    28021 tgaaactgct attaaagaag aagtaaaacc gccaactctt atagtagttg ggagtgttgt
    28081 aggacttaga gaaaagttga acttctttga aagtaagcct ttatttggaa aaagtattgc
    28141 tgtaactagg tctagaaatc aaaatagtgt attggtagaa aaaataatgg atttaggtgg
    28201 aaatcctata gaaataccta ctattaaggt agaaaaaata caaaataata ttaacttaga
    28261 aaatgaaata aaaaatataa ataagtataa ttatctaata ctaactagta aaaatgccgt
    28321 agaaatcttc tttgaaaaga tatatgaaat gaattttgat ttaaggatat tatctaattt
    28381 aaaggtatgt gctataggtt ctgctacatc aaatgagttg aaaaaaagag gaattatagc
    28441 ggatatagta ccaaaaaaat ttgtagcaga gtcactgtat gaagagttag cgcctatttt
    28501 aaatgatgac gataatatac ttatacctag agcagaaaat gctagagatt atctggttga
    28561 caaactcaag gctatttgtg aagtaacaga agtacatata tatagaacag taatagatga
    28621 ggagaaaaaa ggtgagatat tagatatttt aaattctaat gacatagatt atataacatt
    28681 tactagttcc tcaacagtaa ataatcttgt tgaaattata ggaaaagaaa atattaaaat
    28741 attagaaaaa ataaaaacac tatctatagg tcctataact acagagacaa taaatagttt
    28801 gggaataaaa ttgtacaaag aatctgctac atctactata gattcgttag tagatttaat
    28861 tataaaaaat taattttgga ggcttgaata tgttaagaag accaagaaga ctaagagcaa
    28921 gtaaagcaat cagaaatttg gtaagagaaa ctaaggtgaa tgtagaagac ttaatatatc
    28981 cactgtttgt agtagagggg gaaaatataa aagaagaaat taaatcttta ccagatgtct
    29041 atcatttatc aatagatatg ctagaagacg aaataaaaga aataagtgag ttgggaattg
    29101 aacatataat gttatttggt gttccagatg aaaaagatga gtgtgcttca caagctttta
    29161 atgataatgg aatagttcaa aaggcaatta gaaaggtaaa agaaataaat tcagatataa
    29221 atgtaataac agatgtctgt atgtgccaat atacaagtca tggacattgt gggattttaa
    29281 ctgatactgg ttatgttgat aatgataaat cattggagta tttggctaaa atatctgtaa
    29341 gccatgctaa agcaggagct gatatggttg ctccatctga tatgatggat ggaagaatac
    29401 aagcaataag agaagcttta gatgaaaatg gattagaaaa tgttggaatc atggcttata
    29461 gtgttaagta tgcttcaaat tattatggac cttttagaga ggcagctcat tcagcaccat
    29521 cttttggaga tagaaaaaca tatcaaatgg acccagcaaa tagcaatgaa gctataatag
    29581 agactgaact tgatatattg gaaggtgcag atatacttat ggttaaacct gcattatcat
    29641 atttagatat tataagaaga gttaaagata attttgactt acctctagca gcttataatg
    29701 taagtggaga atactctatg cttaagtttg ctgtgaagga aggtttatta aatgaagatg
    29761 taattcttga atcaattaca tctataaaaa gagcaggagc agatataata ataacttatt
    29821 ttgctaaaga cattgctaaa ctgttgaaaa aataaattct agcagtataa agaatatcaa
    29881 aaagtatagg aattgtaatt aactattata cagtagtttt gtttagacat ttattgaaga
    29941 ataatagaaa ctaatttgca atttctatac tttatttatg taactaaata aaatttggag
    30001 gtagaagatg ctatatccta ttaatttaaa attagatgag ttagatgtag ttataattgg
    30061 tggtggagaa gttgcatata ggaaatgtaa aaatttttta gagtttaaca aaaatgttac
    30121 tatagtttct aaacaaattt taaataaatt ttatgattta aaaggaaata taaaaataat
    30181 aaaagatgat tataaagaaa tatatataaa agatgcttct gtaataattg ctgccacaaa
    30241 taatagagag ttaaatatgg aaataggatt atattgtaaa gcaaaaaata agctagtgaa
    30301 tgtagttgat aatatagaaa tatcgaactt tactgttcca tcatatataa aaagaggaga
    30361 tttacttata agtgtgtcta ctgggggcaa gagtccttca ttatcatcaa agataaaaaa
    30421 agaaattgaa gagagatata ctgaagatta tgaggagtat ttaaatgtat taggagatat
    30481 aagaaaaaag gttataaaaa aatacgaaga taaaagtaaa agaaaagatg tgcttaatat
    30541 gttggtaaca cttgacctag aagaacttaa gaagtttgat atataaaaaa taaaataaaa
    30601 aatgttaaaa aggtgttgac ggattatttt taagatgata tagtattact tgtccttaag
    30661 aaaagggcaa acataa
//
LOCUS       DAEHWO010000048        27849 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEHWO010000048 DAEHWO010000000
VERSION     DAEHWO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27849
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.048"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(414..1130)
                     /locus_tag="KNP54_002465"
     CDS             complement(414..1130)
                     /locus_tag="KNP54_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893345.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(1670..2470)
                     /locus_tag="KNP54_002466"
     CDS             complement(1670..2470)
                     /locus_tag="KNP54_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBF0893346.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(2784..3515)
                     /locus_tag="KNP54_002467"
     CDS             complement(2784..3515)
                     /locus_tag="KNP54_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893347.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEICAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(3502..4197)
                     /locus_tag="KNP54_002468"
     CDS             complement(3502..4197)
                     /locus_tag="KNP54_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0893348.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(4199..4990)
                     /locus_tag="KNP54_002469"
     CDS             complement(4199..4990)
                     /locus_tag="KNP54_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893349.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAIILSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILYTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(5000..5812)
                     /gene="modA"
                     /locus_tag="KNP54_002470"
     CDS             complement(5000..5812)
                     /gene="modA"
                     /locus_tag="KNP54_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0893350.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(6446..6646)
                     /locus_tag="KNP54_002471"
     CDS             complement(6446..6646)
                     /locus_tag="KNP54_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBF0893351.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(6871..7047)
                     /locus_tag="KNP54_002472"
     CDS             complement(6871..7047)
                     /locus_tag="KNP54_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893352.1"
                     /translation="MFRDKMDKCTHMLTAYISNSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(7101..7190)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(7370..7570)
                     /locus_tag="KNP54_002473"
     CDS             complement(7370..7570)
                     /locus_tag="KNP54_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0893353.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(7572..7922)
                     /locus_tag="KNP54_002474"
     CDS             complement(7572..7922)
                     /locus_tag="KNP54_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBF0893354.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            8084..8272
                     /locus_tag="KNP54_002475"
     CDS             8084..8272
                     /locus_tag="KNP54_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBF0893355.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGESELKIKKFSILYGSS"
     gene            complement(8749..8919)
                     /locus_tag="KNP54_002476"
     CDS             complement(8749..8919)
                     /locus_tag="KNP54_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893356.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(9308..9796)
                     /locus_tag="KNP54_002477"
     CDS             complement(9308..9796)
                     /locus_tag="KNP54_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBF0893357.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSIKIPNDKNMIITFLSNKS
                     DN"
     gene            10600..10974
                     /locus_tag="KNP54_002478"
     CDS             10600..10974
                     /locus_tag="KNP54_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0893358.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            11079..11453
                     /locus_tag="KNP54_002479"
                     /pseudo
     CDS             11079..11453
                     /locus_tag="KNP54_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            11743..12261
                     /locus_tag="KNP54_002480"
                     /pseudo
     CDS             11743..12261
                     /locus_tag="KNP54_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12693..12947
                     /locus_tag="KNP54_002481"
     CDS             12693..12947
                     /locus_tag="KNP54_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893359.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            12983..13306
                     /locus_tag="KNP54_002482"
     CDS             12983..13306
                     /locus_tag="KNP54_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893360.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            13580..13732
                     /locus_tag="KNP54_002483"
     CDS             13580..13732
                     /locus_tag="KNP54_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893361.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            13926..14849
                     /locus_tag="KNP54_002484"
     CDS             13926..14849
                     /locus_tag="KNP54_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBF0893362.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVRA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   15116..15866
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=15116..15144
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            16057..16209
                     /locus_tag="KNP54_002485"
     CDS             16057..16209
                     /locus_tag="KNP54_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893363.1"
                     /translation="MKNCRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            16329..17142
                     /locus_tag="KNP54_002486"
                     /pseudo
     CDS             16329..17142
                     /locus_tag="KNP54_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            17194..17355
                     /locus_tag="KNP54_002487"
     CDS             17194..17355
                     /locus_tag="KNP54_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893364.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(17683..18147)
                     /locus_tag="KNP54_002488"
     CDS             complement(17683..18147)
                     /locus_tag="KNP54_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893365.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKNKILRERKYKKRR"
     gene            complement(18283..18600)
                     /locus_tag="KNP54_002489"
     CDS             complement(18283..18600)
                     /locus_tag="KNP54_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893366.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(18883..19179)
                     /locus_tag="KNP54_002490"
     CDS             complement(18883..19179)
                     /locus_tag="KNP54_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893367.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKNYLNRF"
     gene            complement(19198..19611)
                     /locus_tag="KNP54_002491"
     CDS             complement(19198..19611)
                     /locus_tag="KNP54_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893368.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(19595..19828)
                     /locus_tag="KNP54_002492"
     CDS             complement(19595..19828)
                     /locus_tag="KNP54_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0893369.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            20047..20421
                     /locus_tag="KNP54_002493"
     CDS             20047..20421
                     /locus_tag="KNP54_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0893370.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEECFKNLK"
     gene            21033..21725
                     /locus_tag="KNP54_002494"
     CDS             21033..21725
                     /locus_tag="KNP54_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893371.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            21921..23981
                     /locus_tag="KNP54_002495"
     CDS             21921..23981
                     /locus_tag="KNP54_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBF0893372.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(24186..24509)
                     /locus_tag="KNP54_002496"
     CDS             complement(24186..24509)
                     /locus_tag="KNP54_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBF0893373.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(24502..25203)
                     /locus_tag="KNP54_002497"
     CDS             complement(24502..25203)
                     /locus_tag="KNP54_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBF0893374.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(25481..26866)
                     /locus_tag="KNP54_002498"
     CDS             complement(25481..26866)
                     /locus_tag="KNP54_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBF0893375.1"
                     /translation="MPINSFENYPMNWKRKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(26974..>27849)
                     /locus_tag="KNP54_002499"
     CDS             complement(26974..>27849)
                     /locus_tag="KNP54_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBF0893376.1"
                     /translation="EIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTRCKIII
                     PEKKYNNKELRFIFKHELIHYKRKDNLFKLLISIICIIYWFNPILYLLKKYFHELCEL
                     SCDEIVIDKCTTSEIKEYAYIILDTIKYQKSLKYSSFVSQFLNKKNIILKKRLDSMFN
                     QDKKKINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGTHIIDS
                     NGNSIEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPL
                     YDKEGIKIIGRFEIN"
BASE COUNT        10777 a         3283 c         3813 g         9976 t
ORIGIN      
        1 tgtagattat taaattagtg ttgtaaaaca ttttattact tgtaaatgca tgaaacctta
       61 aggttaatag tatcaaagtt aatataagtg taagttctat ttttacctta gaaaaaaggc
      121 ttatgacatt ctctaagaat ttgactttag tctgtttatt ttttttatac aatgtaaaac
      181 atagtatagt caataaaaaa cttgataata taatacctat gcagacaaac tctaattcta
      241 cttttgacaa atgtacagga gtaccgaaaa aataaaaata agggagagca aactctttat
      301 aataataatt aatattataa gaaaagttat tattcaaatc ataaactgct tcaaataata
      361 tagaaactaa tagaaacagt aataataata aaataaattt tgctttagaa tcattaataa
      421 ttaagttttt caattttgta accaatgccc cacaccacct ttaaatattt tggttctttt
      481 ggattaattt caatcttttc tctaattctt ctaatatgaa cagcaatagt tctctcacaa
      541 ctataagcat cctcattcca gacattttca taaatctcat gagaagagaa aattttacct
      601 tttcgtgaca taagaagtgt aagtatttta tattcaagtg gtgtcatttt aatttcttca
      661 ccatctaaag aaactatttt tgtatctgta tttagctcta ggccaccact ttttagaata
      721 taattagtat catttgagtt atttgtatta ctaaaatcac ctaaatttat ataccttcta
      781 agttgagatt ttactcgagc agtaagttct agtggattaa atggtttagt tatatagtca
      841 tcagcaccca tattaagacc tataattttg tccatatctt ctgattttgc agataagaga
      901 attattggta tattcctttt ttctcttatt ttaagtgtag ttttaagccc atctaaattg
      961 ggcatcatta catccattat tattaactta atatcatttt cgattagtat gtccaatgct
     1021 tcaagtccat catatgcctt taaaacatta aagttatcag gtctcaaata gaactctata
     1081 gcatcaacta tctctctatc atcatctaca accaatatat tttgattcaa cttattaacc
     1141 cccttgaaat tttattttta accaattttt attttatacc aaaaagaggt attagaaaac
     1201 agtaagcccg ttcattatga aataaaaact agtactttta atatattgtc aatgcatata
     1261 gtaaatttaa aagtatagac gcccatatta atctgaaggt aaaagtttat gaaaatatct
     1321 agggtaatct atcacactcc ttatgttatt ttggtttatt aattttttag gtttaaacat
     1381 atattaacaa atataaataa caaatgagtt tcataattat taagaattta taacaaatat
     1441 ttattttaat gtagtttaat ataaataggt agcttaatgt agatatgtat aaagcattta
     1501 ataaggctta taggttttaa tgatgatatc tttatatatt ttaagagatg atgaaattag
     1561 atatgggtaa tagttgtatg agaaaaagta gtatagcaca aaaagtgcta tatcacaaaa
     1621 tctcaaataa tttccttttt ataacttaaa ttaaaagaat aaatatttct tataaattag
     1681 gtgtatgaag tatagcagga acatctttat tatttaataa cttatcaaat gatttatggt
     1741 cagacttata gccaatacct tctctatatt ctaattcatc aacaattttg tattgttgac
     1801 aggcattttt aaccttttca tagtcttcag tagaatgagc tttataaact atcttattat
     1861 taaaagttat tttatcagca aatttaggtt ttacaaaata tttagcatct tttattttac
     1921 cagcattata taaattttgg ataacagaac cattttttaa atgttgtaaa tggtcatcta
     1981 acttataagt atgtgctata tgagttacat ttttaaattt ttcttcaaat gtaagagcaa
     2041 ttttttccat gtaattgaag tcagtattac catttgtatt tgtttctggt aataatatta
     2101 tattttccct tattacacca aggctattaa gagaagctaa aaattctcta tttctatatt
     2161 ctgatttttg tatatttgtt aggttttcat attttttata tttatcaaag acggatatac
     2221 cacatccagt agatactaaa accacaaata catgattttt tcctctttct tttatagcat
     2281 taacaatagc actcccagcc cacaacactt catcatcttg atgctgaaca tagaagacaa
     2341 cataatcttt aaatttttta tgactataat tcacatagct actaaaagcg gttaaaatca
     2401 aacataaaac tagaataata gatagaattt tatatttatt tatagtaaat tttttattct
     2461 taaatgtcat ttaatcatct cctgaaaagt tgtcttagtt atattatcaa acaaagtact
     2521 aaaaattatt tcttaaatgc tgaaaaatat agagtagatt aatggaataa aattttttta
     2581 ttagtttaaa ataaagaaaa catttatgta taagactaat caaaatatta atgattgata
     2641 ggaattgaga tttaaaggga ttgtacattt attcgggatt cattttaata gaattttact
     2701 ttagtactta gaataaaagt aataactttt taaatttaaa gagtacacat atatatttgt
     2761 gtactccttg atgatatgat tgcttattta ctacaaaaac agagtctttt taaacctaaa
     2821 atatttgatg caccagctat cgtagttcca taatagtaaa ctggtttgtt aagtgataga
     2881 aaatttataa ttgagttatt acataatgta cttcctgtgc aaatcactaa atcagcccaa
     2941 gatattacat cttcataatc tcgtatacca tcttcaatct taacattata ttggatagta
     3001 tccacaaatt caggatttaa atctaatact cttgtttcga aaaagtcctt aatattatca
     3061 attatggctg gttgatatcc tataattgct acttttggat taccaaattc catttttata
     3121 aactcaggga atttttttgc acatatctct ggctcgttat ttttacaatg aatggttcta
     3181 tccgtcttgc ctaagtattt cataactgca tttaatgatg ctataaaaag acttctatca
     3241 tgaggattgt catgtaaatc taatgataat atgtctttta aagaaccttc aaatgtagat
     3301 ggagtagaag taaatgcttg tcctttagct cctttaaagt cagcttcaag cattatttct
     3361 ttaccaacta taattgggaa atctttacgc ttagtatttc caattgcttc ttttgaagat
     3421 agagatttgg acacaatact tatcatatcc atatttaaat tatatttatc aacttgtact
     3481 aatagataat ctctcaaaat atcaaatata ttcatagaaa aaagattctc ctttattttt
     3541 tatttcttca tttaaatcaa aaatatgatt tatttttcca ttgttcatta ttcctatctt
     3601 atgagcaaaa aacattgctt cagaaatatc atgagtaaca tgaatcactg ttggtttgta
     3661 ttttatgtag acatccttca aaattttgct tatatgtttt tttgtaatat aatccaatga
     3721 actcataggt tcatctaaaa gtaatatatc aggttcagct attaaggcac gtgcaaaagc
     3781 aactcgttgc ttttcacctc cacttaaatt tttaggatac ctatttttta tatcttctat
     3841 ctgcattaat ttagataagt ggttagcctt aagaatctgt tcatctatag gtatttttct
     3901 caatttaagt ggaaacctta tattatcttc aacattcata tttggaaata attcaaaatt
     3961 ttgatataca aatcctatat ttctattttc tggaggtaag tttgatatta aattttcttt
     4021 gtatgataca tttcctttag cagatggata tcttcctgct aatgtttcta gaaatagagt
     4081 tttacctgac ccactagctc ctaataaaac aaagtattca tgattattaa tatttaaact
     4141 attttcttgt aatttaaaat taggtaaatc aagagataaa ttttttattt ttaacatatt
     4201 aattcttatc aacctctcta ttaaaaaata tctcaaaaag catcaagcat gtaagtgaga
     4261 taaatatcaa aattacagct attccgattg caatgtctat atcaccagta gacatattta
     4321 aatatataga tgtaggaata atttcagttt tcatacgtgt agaacctgct atcatagcta
     4381 ctgcaccaaa ttcaccaagt gctcttgacc aagtcattac agttgcagat atgattccag
     4441 tttttagatt tggaagaatt ataaatctaa atgcttccca actattacat ccaagggtac
     4501 gtgcaacaaa tatcatcttt tcattacttt catttagtga agtgtaaagt attttaatag
     4561 taagtggaag atttacaaat acttgtgcta aaactatacc ttgctttgta aatataaaat
     4621 caagcttaaa aatcttataa atggaatctc caatccccat tcttccaaac aaaagtaaaa
     4681 gagcaattcc tgatactaag tgtggaagag acatagggag atttattatc tgtataatca
     4741 gttttttaaa tggtaattta gtaatatgta aaaaatatgc tactggaata gctaataaaa
     4801 ggcatactat agtagatatt aaagatgttt taatactaag tattattgca tactgtactt
     4861 ccactgattt taagcatata ggaacataac ttatcccttt aatgattaac ataagaagtg
     4921 gtgatacaat aaacaaaaag actatagcaa aaaatccagt aagtagagta gtaaaaaatt
     4981 tatttttcaa gtttaatcac tacttaacag gttcaaaacc atatttttta aatatctgtt
     5041 tagcttcgtc tgactctata taatttataa atttattagc taaatctttt ttatcactat
     5101 agtttacgat tcctgctgat ataagttggt ctatattttt atcttgggca atttctataa
     5161 cttctacatc ttcattgcca aagaccgaat cttttgtggc tattgtagca tcagctttac
     5221 ttgatgttaa ctgtacaatc atttcattta cagttgcagc tgtagagaca acattatcat
     5281 ttatagattt taaattattt ttttcaagta ttttttgtgt agtcttacct atagcattag
     5341 actctttgtc tcccaaaata agtttaactc catctttatt taagtcttcc aatttttgaa
     5401 tattagctgg atttccttta ggtacaacta ttgcaggtgt atgatgtgca accgttttat
     5461 gttcacctac aagttctttt tcaaaggctt ttgaataaat tggttcagaa ccaacaataa
     5521 atacgtcccc tttgtgactt gtctcaattt gagctattag ctgtgcagaa cctgcatagc
     5581 tatattcaac tttgacatta ttttctttct caaatttttt tgctatttca tccattggtt
     5641 tctttaaacc tgcccctgaa tagacaaaaa gagtctcttt ttcttttgaa tcatcagctg
     5701 ttgtcacttt agtattagat tcatcattag ctttgttttc tttagaatta catgcagtaa
     5761 tacttaatga aataatcata gctaaagcta gtactgaaag ttttttaaac ataagatatt
     5821 cccccttagt aaattaatgt aaattctttt ttagtatatc atactaagaa aacgatgtct
     5881 aagtttttgt tatgttttat aatgttttgt tatgttttgt tatgtatagt taagaaaaaa
     5941 tctatttata atgttatttc tataggtagt tattttattt ttaattttta ttaatacttt
     6001 aaagtatttt aaatttaaaa acttaaatca aattaactta ttgtagattt tttacttttt
     6061 aactaatttt atatttatta tatttcagtg aaaaaataga acattgaaac atatagatat
     6121 gttttaattg ctttttatta acaaattact aaaaatgtta tatcagaatt gaatacaaaa
     6181 gaaagagtat gtatttatga gatagttgaa aattttgatg tgccacaact aaaattatta
     6241 tattactata tatttaatta aaagagtact tgtaggttta agtacatact ttataaatat
     6301 atttttgtta gatttatttt ataaaaagta tttagactaa gtattatttt taagtatttt
     6361 cttgttgaag ttattttttc cttttttaca aaattcgtaa ataaaaaaaa gactcttaaa
     6421 agagtctttc cgaaaaatct atatattata atatagttat attttctgct tgaggacctc
     6481 tagcgccttt aactatatca aagcttactt tttgaccttc ttctaatgat ttaaatcctg
     6541 aagtttgtat agctgagaaa tgagcaaata cgtcatctcc actttccatt gatataaatc
     6601 caaatccttt ttcattatta aaccatttta ctattccatt attcattaaa aatactccta
     6661 ttaacctata tcaagatata cttgatttac ttgtgtatta ccacaaatat tattgtatca
     6721 tagattaaca taaatgtcta tttaattata atttttagtt aacattttta tttattctta
     6781 atatgaaaat aaatttaaac attttatatt accaatatat taatgtaaat gtagataaaa
     6841 ctaaaaaggg ttttctagaa aaaaatctgt ctaattatac ttacttacca ataccatcac
     6901 ttgatgcaag caagattcca caactttttc tccgtactct aatataaaat catctaactg
     6961 tgtatctata aaatcacaat aatcgtatga attactaata taagcagtta acatatgtgt
     7021 acatttatcc attttatctc taaacataat gtatttatcc ccctaaaaaa ctttcatgaa
     7081 aaacaaaaag aaaatatctt tttggcaact ggctgacata acttatttta taagcgttag
     7141 tccctatagc tttgcgtcac taaatttctc tagttttgcc gatttagttt tattctacag
     7201 attaataata caatagaatt agttatcatt caacatatct agttgaataa ttaataaatt
     7261 tatatatgaa ctttaaatta tttgaaaaaa taaaaagccc ctctgtcagg agtgacttaa
     7321 aaattgaatt taagtttgta tttaaaacac atttttaata atgcaaaaac taatcaaaaa
     7381 taaacaattc atcaataggt gtatctacta tttttgatat atctattgct aatttcaaag
     7441 aaggattata ctttcctgct tctaaacgca taatggtttc tcttctaact cctacttttt
     7501 ctgctaattg ttcttgagtt aattctttta attgtctata tttttttagg ttacaagtga
     7561 atttaggcat attatttttc ctctaaaata taaagtttta tagcataaac atttaaagtg
     7621 attgcatatg taattgatag taaaacacac attaattcta tattcctaga cactatagta
     7681 atacaccata aaatgaataa ttctataata gcaagctgtc ctgtaaatgc catagctgct
     7741 ttttcatctt gtacatacct ttcatctgct ttatcaccat ttatttttgc tataataaag
     7801 tttgagaaaa aagcaaaaaa tccaatatat gtaaggtcag caacattgcc agatgaaaaa
     7861 tatctaagac ttaaaaatcc aaggaaacca caaaaaccca taaaaaattt tttctgaatc
     7921 attttttatc ctccttagta attttaaaag agatatattt atatctttat gatacaaata
     7981 tatctctttt atattctttt gtcaatagaa aatcagtatt atacaatatt tatactgcac
     8041 cataattgtt agagcaaaaa tctaatgctt gagatgttta tgtatgacta aatatgattt
     8101 taatttcaaa ttaaaagtag ctaaatttta tttgaataga gaaggaagag atattttaat
     8161 agtaaaacaa tatggagttt atgaccattc tcaagttgaa agatgggtta atatattagg
     8221 agagagtgaa ctaaaaataa aaaaattttc tatactatat ggttcaagtt agatgttata
     8281 aactatatga tgataactaa atatagtgta caataaatcg ctaagtattt tggaataaac
     8341 aatagcacag ttatagcaac atgaaaataa aaatttttac atagtggtgt tgatgccttt
     8401 tctaaaatga aaggaagacc ataatgaata aaaacaaaaa cactaaagaa aaaataaatt
     8461 aacaagagaa caagaattag aatatgaaaa taaattttta aaagatgagc ttgagttttt
     8521 aaaaaagatg tgtgtctcag ggaagccaca ttaaaaaaca gtggtatcat tattaatcaa
     8581 aagaaagtta gatgtattat caaaaaatta gaacttaaat gcatagcatt ttttcataaa
     8641 tcacataaat ataactccta taaaggtata attggaaaag taaaaaataa taaaacaaat
     8701 agaagattta aaacatcaat agcatatcag aaaataacaa atgatatgct agaatttata
     8761 aaatatatct aatgataaaa atggaaaatc aattataaaa aaggcatatc tcgattcatt
     8821 ttttgttata tagtcaaata agaatactat agatgaaaga tacgattttg catatgtatt
     8881 aagtaagtat tctgatgttt ttggttgata cacatgcaat aaagaagttg tgtttgcaga
     8941 taaattagca aaactatagt ataagttgca acaataaaga aaatgaaaat tatcatacta
     9001 aagcataagg catgttacaa ttttattaga taggacatta acatacacta aagtactttt
     9061 tattataaag agtacttatt tttttgaaat tcattaatgt ataaactatc aagaatatta
     9121 ctcaacataa tttaaaaaca acttgaatag gtatttttaa attatgtgat ataataaaaa
     9181 atagaagtgt atgccaatac acttctgtag ttataactaa gcattctatt cttgaggagt
     9241 gcttttttca tttttataac caactctttt tactttaaca ataattatca gacctatata
     9301 tttattttta attgtctgat ttattagata aaaaagttat tatcatattt ttatcatttg
     9361 gtatttttat tgaactacca taatcttctt ctaatttatc tagaccactt ttacttattt
     9421 ctccatctat aattatgttt aattctaagt attcttcact accattagat gacactaaag
     9481 tgtacgaacc attataaggc atgcctaaat tttctatttt atgtgccaaa gggtcttcat
     9541 caccaatacc agagtttact gttatttttc catctttttt agtccaccat attatgtttc
     9601 cttcagtata ttttgattca tctgcatagt agctaagaga cgcacttttt attgcactta
     9661 tatcagcttc aagtttagct atctttgctt tttctatatt tttaaataat gctggaagtg
     9721 ctactattgc caatattcct attatagcaa ttactactaa taattccact agagtaaatc
     9781 cttttttatt tttcatttat ttcccctcca tataaaatta ataatatata aatttttatt
     9841 ttgttaattt ctactttcta tattttacca tatatagaca aaaaaatcac tttctatgac
     9901 aaatatacta ttattttaca atttatggaa atgatttaaa atgacatttc ttgttagaaa
     9961 agatataaga aatggattaa aataaagaaa actacagtca tatcaatgtc aataatatta
    10021 tttaaaagca gatgaaaata aaaagaggac tcagaaaata atgtctattt aattatactt
    10081 acttaccaat accataactt gatataaaca agattatact acattttttt atgctctagt
    10141 ataaaatcat ctaactgtgt atctataaaa tcaaaataat tatatgaact atcagtataa
    10201 taagtcaaaa tatgtataca tgaatacata ttttaaaaga tatatattat tacataccta
    10261 aaaaactttc ataaaaacaa aaataaaata tgcttttagt aacttgttaa cataacttat
    10321 aatttatttt ataagcatta gcctatatag ctttgtgcta ctaaatctct ttgattctaa
    10381 cgatttagtg ctattctaca actaaaataa tacaatagag ctatttattg tttggtagca
    10441 ttgtttgtaa attaaacaaa tttatacata tgaatattat tttacattca aaaaaacaga
    10501 ctaaatatgt agaatatttg gtaaaactta cctctagttt ttgtcttaaa aagctcctat
    10561 tattaactta agttagaaga attaaggaag tgacataaat tgaaagaaga aatattaata
    10621 gaaaaattat taagagcaga attaatagta atggagtatt tatggaaaaa agacactcta
    10681 atgcctaaaa aagaaattgt aaaagaaata aaacagattt atggatggca taaaagtaca
    10741 ataaaaatac tactaaaaag gctagttgct aaaaggtatt tggctagata tattataaat
    10801 tctcaatctc attataaaat aatagatagt aaagaatatt atacttttaa gaaaaaggta
    10861 ctaaaatcta gtaaaagcat aaaaataatg cgttcactta ccactacaca taaaaatgta
    10921 agtaaagaga agttagacct attagatgag tattatagaa acttaaaaga atgatatagt
    10981 aaaaatcgaa tgtaattatt taccttaatt cttttgtttg taaaacttta ttgatacaga
    11041 atttaacata tacataaatt ggtaaaggaa tgtatactat gaaaattagt aaattaccag
    11101 aagcggaatt aaaagttatg agatatattt gggaatcaga aaaggtatta atatcaagag
    11161 aaatcaccaa gtctatggaa caaaaatatg aatggaaaga tacaactata tttacagtat
    11221 taaaaagatt actaaagaag agagttttta gaagcggaga aaatagataa gtgtacacac
    11281 tataatgtat tagtaaaaaa aaataatatc agagatttta aacaaaagaa tttttaaaga
    11341 atacacataa aaattcaata ttaagtttaa tgtcagcact atgtagtaag gatgatgaag
    11401 tagatggtga tattttaaat ttattagaag aatattttaa gaatttgaaa taagaaaatg
    11461 acaaattgat acataataaa taaaatgaag gtatgaaatt ataacttttt ctaccttcat
    11521 tttgtttatt attctgaaca tgttaagaaa atgaaataag tttgtatttt atttatataa
    11581 attttaatag aatatgtata gtatatagta gatagaatgt ataaaaataa aaactgttca
    11641 ataagaatta atatacatta attcagctga atccaatcaa aatacttaaa taaaagtaat
    11701 ctgaaaataa cataattcaa atcaatttat tcaaataaac ctcaatttat ctcaaatctt
    11761 aagaagtcat taaacaaact tgctaaatta caaagagaat tatcaagaaa aacaatcggt
    11821 agtttaaata gaaataaagc aagattaaaa gttgcaagac ttcaagaaca tatagctaat
    11881 caaagaaatg attttctaca aaaactatct actaaattaa taaaagagaa cgatattatt
    11941 tgcatagaag atttacaagt aaagaatatg attaggaatc gtaaactatc tcgctcaatt
    12001 tctgatgtgt catggtcaga gtttattcgt caattagaat acaaggctaa ttggcatggt
    12061 agacaaattg taaaggtggg taaattcttt gcaagttcac aaatatgcaa taaatgtggg
    12121 tataaaaacg aggaagtgaa ggacttaaat ataagagaat ggatttatcc tagttgtaat
    12181 gaaactcacg atagagatat aaatgcaagt ataaatatat taaaagaagg attaagacta
    12241 ataacaattc aaaataaata acgtatgtaa gaaccgtagg aactacgggg atagcctgtg
    12301 gagaattagt aagacatatg ttagtatgca aaattctgtg aagcaggaaa cctgtgactt
    12361 tagtcatggg aggttcaggc tagtattact cattattgta ttcaaaagct aaagtggaaa
    12421 cctagtgaat atatgaattt agaagttaat gagagagcat tagcagccga ctcaatactt
    12481 attaaaattg aagatgaaga agaaacaatg aaagaagctg aaagagagaa aaagagaggt
    12541 agaagaaggt agaatttaaa gttaaaatag ttacattgct aatatatgaa aatgttacaa
    12601 atttggaaat agatggatat atatgttgta tagtataatg tagataatat atcaccaagt
    12661 aaaaaacaac aaataaatct aaattatgag gggtggaaaa taaagatatt aaacttacaa
    12721 tatgtatatt tgcttttgta attggaataa tagtgttatt ttgctgtata ggtctaggtc
    12781 aatttaatat ggattgtatt ataaaacaaa atggtgggtc aatagctacc gaacaataca
    12841 acatatattt agaacaatct atttcacaat atagaaattt tggttctata ctggttttac
    12901 taggaggaat aggaatactg tttgataaaa gtgtcagaaa atactaaaaa agtatatttt
    12961 tatttaggat gtgatgaatg atatggcaag agatgtattt agtgtaaaga tgacaccact
    13021 agaagcacag aaaatggtag aaaaaaattt ggaagcagat ttagtttctg ttgatattta
    13081 taacctagaa aataataagt ctataatagt tacaatcttt gaaaaatatt atgcaagaag
    13141 caatagtgat gcaggtttgg tagtgatttg tgaaaatact acaggaaaaa cacttgttaa
    13201 aattacctca actggtagtg caattggact atttcagatt gattggggaa caggtaataa
    13261 tttgattaaa agagtaaaaa aaatacttat tgattatatt atttaattat tttatgtaga
    13321 tattcttagg ttggtatgga atttgtacta acctattaag taatcaataa aactaaataa
    13381 acatagaaag cacttacaaa tatgtaggtg ctttttattg aaaaaataga aaataaaata
    13441 aaaagtaaga tataggaaaa atatgtaaga attatatgtt ataataattg tagcaagaag
    13501 atgtaatcta caatttatag agtggagttc atgtattaaa aaattatcct cccaacgata
    13561 agaagggagg tgaatataca tggataattt tttatttaat gtgttagcta gtgtaacagc
    13621 tagttacata gtttatttga ttagcaagtt aatcaaaaaa gtaaaaagcc actctaccgc
    13681 aaagagtgac ttaaagattg atataaattt taaatatcat cgtaaaaaat aactttcagt
    13741 tatagaactt cactctaccg caaatagatt gtagttcttc ttgtttttat tataccacaa
    13801 attagaaaaa atattgcata taatattttt tatagtcaat aaaaatatga aattttttat
    13861 acacaatgat gatgaatcta actagatgaa taaatttaat tgtaaataag aaagtactta
    13921 cttaaatggt aggtgctttt gttttgccaa attatgctat aatattgagt gagatgagta
    13981 atttgtgggg gaattttata atgtggatat tagtaccaat aataacaata gtattactta
    14041 taatagctgt ttcttctatg caatatattt tagttatgat agcttttttg ttgattatat
    14101 attcttttat agaaaagaaa atagttatgg gtcttgtgtc agttcttttt ttcacttatt
    14161 caatttatct ttgtgcaact tgggaagata aatccttgat agcagataat aaagttgaga
    14221 ctgttagggc acaaagagaa actgtagaaa gagaaaaaga aatggaaaga agaagaatac
    14281 aagaagaagt agacaaagaa agatatattg aaaaacatgg aatggaaata tcagaaaatg
    14341 atttaaaagt taagctagag gctttagtac ctcaagaata taaggggaag aaatatgaat
    14401 taaaagtagg aaaatttaaa agatatagta tgtattttga tttaactgta caaaatgaaa
    14461 aatttagtaa ttctgaagaa tgtaaaaaat ttgtaaaaga aattgctaat gatcttaaaa
    14521 aaattaaaat aagcaaggcg tactttaagt ttcattcaaa agatgacggc ggtatatata
    14581 attctgttta tattgattat tttagaaaca tacaaaataa tgtagataat gttgaaaatt
    14641 tagaattcaa tgagtttgaa cttaaaaccg aagaagaaga gaagcgagaa caagagaaaa
    14701 tagaacaaga aaaaaacagt tataataact acattcaaaa cagagtggtt gacccactag
    14761 atagaataaa gaaactaaaa gagttgctag attcaggagc aattacacag gaagaatata
    14821 ataaaaagaa aaaagaatta ttagaataga taatatagta agcacttaca agtatgtagg
    14881 tgcttttaaa tttacaaagt attccatttt aattttatag tttagatttt atgatataat
    14941 aaaaatatag aagttttgca gtgtgcgata tttgttacaa agtagggctt aatacttgaa
    15001 atctaagatg ttgagggtgc gtgataagtg ttatcaattg cactattgcc cgctcactgc
    15061 aattttaaga gtattgtata tatgtaggta ttggaaatgc taagtttatt ttggggtttt
    15121 agattaacta tatggaatgt aaatattaca tgggtaaaaa ttttgatgat ttttatgaca
    15181 gttttagatt aactatatgg aatgtaaata ttacatttaa tttgcattgc tttgatgact
    15241 tctttgtttt agattaacta tatggaatgt aaatgcgtac aaggttgaga agctccgcaa
    15301 tctcaacgtc gtgttttaga ttaactatat ggaatgtaaa tatttgaaag gaataaattt
    15361 taaatgaatg aaaggatagg ttttagatta actatatgga atgtaaatca gccaaaaact
    15421 tcgaatttga actaaaatgc gtgggtttta gattaactat atggaatgta aattctcatg
    15481 actattgaat aaatataata aacaagcata cgttttagat taactatatg gaatgtaaat
    15541 ttagaatcaa aagcacttaa tcctagttct ttcatagttt tagattaact atatggaatg
    15601 taaatagctt tttagcttcg tctactactt tataagcaaa gcgttttaga ttaactatat
    15661 ggaatgtaaa tgatgaacaa taaaacaatc atctaaagac gaagaaagtt ttagattaac
    15721 tatatggaat gtaaatgttc ctgttgtgtt ttttactaat cccattttat atgttttaga
    15781 ttaactatat ggaatgtaaa ttgctgtgat ttcactaata aaacaattaa taattgtgtt
    15841 ttagattaac tatgtggatt caaaattaaa taaacaaaga aagcacttac aaatatgtag
    15901 gtgcttttat tctgctcaaa attggtcggt tgggtaaaat cattagaaaa aattagtaaa
    15961 aacctctttt ctgtaactcg ttacaatatt attattaatg taacgagtta cagaaaagag
    16021 gtgaataaaa tagcaactaa aagtagggca gagtatatga aaaattgtcg aaaagataaa
    16081 agaggtttta gtgtactttt agacaaagaa aagttagata aatttgatga agtattagag
    16141 gaaaagaatc taaccaagaa agaatggcta gaagaaaaaa tcgacgagga actggaacaa
    16201 aaggaataaa aaataagggt cactcccacc gaccaaagtt tgagtaaccc ctatgatgta
    16261 tactatcgta tatcaattat aatatatgtc attccttaaa aaaatcaatt attaaggagt
    16321 gtaatattat gaaaaatgaa ttaatgatgt ttgaaggaaa agagattgaa gtatttgaat
    16381 ttgaaggaag aattttattc aactcaaaag atgtagcaaa ttgtttagac ataaaaaatg
    16441 ttaatgagaa tataatactt atgaatgaaa agcaagttgt aaagttaaga aattcggata
    16501 tcagtaatac tgacatccga aaacttaata atgctggaga aaattttctt actgaaagtg
    16561 gagtgtataa attaatcttt aaatcaagaa aagaagaagc tgagagattc caagactgga
    16621 taagcgatga agttttacca agcataagac aaactggtgc atacataact aataatgtaa
    16681 tcccgaaaag ttgagagaaa aagcaagtga gattgaaaaa ttacagttgc ttataacagt
    16741 acatctatgt taaaagaatt gctagatgat gcaggctttg acaataaatc aaaactatta
    16801 acagctaaaa cattatataa gaaagcagaa attgatttac caatagagat aaacgaagaa
    16861 gaacattatt ttgatacaaa acaaatagca tctaaactga aaatatattc taagagtaat
    16921 aaaccagctc agatggctgt ttgtgagatt attaaaaaga ttgatttaga agatggtgaa
    16981 gttaaaggtg tttgggaaat taatggttct tggactggta ctgtaaataa atatacaaag
    17041 agtgtaatag ataaggtgag aacttggata gaggaaaata atagacctac caagattgca
    17101 ggtgagaaga agaattatta tgtattttac aaaattgagt aaatttatca gttgtattaa
    17161 ataatttagt ttagttttgg ggggattaat acaatgtgtg agaatttact tgataatatg
    17221 tatattgaaa agagaaaaga agaatataga attaaacttt tgaaaataag agaaacagat
    17281 atagatatat ataataagtt agaaagtata gtatataaac tttctgagaa aaaattagag
    17341 aaaaataata aatagacata taaagcactt ggatattcta ctgtttcaag tgcttgtttg
    17401 gtataaaatg gtataatgga gatagagaat tatattaacc aaaaaatgga gaaaatagag
    17461 aagatgattt agttgacgct ttatcagtag gagtacctgc aggtaagaca gaatctctag
    17521 tacgattagt tggagatgga ataagtgata ctcaaaaaag tttaataaat aaaagagaat
    17581 ttagaaatat aactcaaatt ggtggaaatg gaaatgagaa agcatttagt gaagtagaaa
    17641 acttagttaa atagattaga aggtagcaac tagagttggt tgttaccttc tttttttata
    17701 ctttctctct ctaagtattt tatttttcat atcttctaat acatctaatg cagtagtata
    17761 aaattgtata ttatttctat aaggtatagc tattggaaga atgcccttgt taactaaaaa
    17821 aataagaagt acaataaata aaagtgtcat aatcattcta ataaaataat tagtgatatc
    17881 tgataaatca aatgttaagt taattgttgt agaaaataca acagccataa tagatatata
    17941 caaagcaaaa atggggttac tatttttttg taactgtcct ttaagcctag attgctctat
    18001 ttctatatct tgaatacttt ttatggaatc catttcacta taatacttat aaacttttaa
    18061 ataatatttt ttatacttgt ttaaagcttc ttcattatct ttaaggtctt tgtcacttaa
    18121 ctctgattta acttccccaa aatccataaa atccctccta caatgttata taatatactt
    18181 taatttatag catatttaag aacttatatc agcaatttgt cgaacgattt tagctaaaaa
    18241 tagagtataa tgataggctt attatttata agatattatt ttttatatag ttatatattt
    18301 ctttctaatt agataatata atgctgttgt tataatggct actaatatta ttgctattat
    18361 tgtaatatct aatcttcttg taaataagcc tattgctata tactcaagac ctgttacata
    18421 gcgataaagt acttctagtt taacagtttt tttcttatct atatttccat atattgattc
    18481 taatttatta aaatattttt tactacaaaa agcagtttta ggtttaatta aatatattat
    18541 tgtagttcct attataacta ttattccaat aagtataaga ttgatatttc caaaatccat
    18601 agcagatacc tcctattaaa tttgcttttc ttaatcaaag tatatcagta acacaagtac
    18661 aaagagtatc taaaatatta caaatattaa caggatagat aaaactatag taaaaattgt
    18721 aataataaag cgaacgaaaa ttatcatact aaaacataag acatgttata attgtattag
    18781 atagaagatt aacatacacc aaagcactcc ttataataaa gagtgcttat ttttttgaaa
    18841 ttcatcaata tataaactat caagaacctt attcaacaca ccttaaaatc gatttaaata
    18901 gttctttttg ataacataat ttatatgata taataaaaaa atagaagtgt accaccaata
    18961 cacttctata gctataacta agcattctct tgctggggga gtgctttttt catttctcca
    19021 aacaacatta tttacttcat cagtaattat caaatcaatc tcattatctt tcaaaatctc
    19081 tgttgcagta caaattagat tatctaagtc aaaacttcga gttatctcta gttgtttgtt
    19141 atttacttct ctttttagta tataagtttt aaaatacatt tatatcaccc cttgtattta
    19201 ctcttttttc tctaaaaata tattgataag taaatatgca acaaataaaa aaatctcaat
    19261 gacacatagt gttatagcta taactagaag tgattgattt ttccatgcac tataagctat
    19321 gatgaaaaga aatgtaaaag taaataatgt ataattcata attttaacta agatatgact
    19381 tgttttcatt gttaagtaca agtctctttc atctgtacta tcgtgtaatt cttcaacaat
    19441 gccttttctt gaaaaagcat tacaaaaatt aaagattgct attacaatta aaagaaatga
    19501 tgaaattagg aatcttttat cttttaaaat gcaataaata actaaactag cacaacataa
    19561 cacacaaact ataataccca ctataaaact tcgtttactc tttactttca tgttttttat
    19621 cctccatttc tttattttct tttaaacaac atagttcttc aatcgttgta ccaaacactt
    19681 gtgccatacg ataggcaagc ataagagaag ggctatattg ctctttttca atagaaataa
    19741 ttgttctgtt tgatacatgg actaaatcag cgagttgttg ctgtgttaga cccatatttg
    19801 ttcgaaattc tcgtactttt gttttcattc cataacctct ttctatatga agctaacttc
    19861 atgtgaagtt aacttcataa tatcctaaaa tgagtaaaat gtcaatctca ttagataagt
    19921 attataaaac ctaaaagaat aatatggtaa aaattggatg gaattattta ccttaattct
    19981 cttgtttgta aaactttatt gatatagaat ttaacatata cataaatcgg caaaggggcg
    20041 cgaattatga aaattagtaa attaccagaa gcggaattaa aagttatgag atatatttgt
    20101 gaagctaaca aggtattaac ttctagggaa ttagttgctg caatggaaga aaaatatgag
    20161 tggaatgaat caactacatt tacagttttg aaaagattag agcgaagaga gtttttaagt
    20221 acagagaaaa taggcaaact tacacattat aatatactag taaaagagaa aaaatatcta
    20281 aggtttgaaa caaaggaatt tttgaagaac atacataaaa attcaatttc aagtttaatg
    20341 tcagcgttac atggtgaaga cgacgaagtg gatgaagata aattaagtga actcgaagaa
    20401 tgttttaaga atttgaaata agaaaatgac aaattgatac ataataaata aaatgaaggt
    20461 atgaaattat aactttttct accttcattt tgtttattat tctgaacatg ttaagaaaat
    20521 gaaataagtt tgtattttag ttatataaat tttaatagaa tatgtacagt atatagtaga
    20581 tagaatgtat aaaaatagaa tttaaataag tagctattat tgcagtgaaa tgaatgtttc
    20641 taagtatatt tgggtggaag aatggtggaa gaaaattagt gaaatgtaat tcttccacca
    20701 ttcttccacc tagaaaatag aaactgttta ataagaatta atatacatta attcagctga
    20761 atgcaatcaa aatacttaaa tgaaagtaat ctgaaaacaa cataattcaa atcaatttat
    20821 tcaaataaac ctcaatttat cttaaatctt aagaaatatt taagaattag gataatattt
    20881 tcttaagatt tatattttat tatatagtta taagggaaag ttacaaaaat gtaagccaaa
    20941 gtaatataac aatttagtca ttgttgagaa agggagtgaa agatattgta taatatagat
    21001 aagtattatt atacaataga ggaagtgaaa atatgtacaa tatattagta gtagacgatg
    21061 ataaagaaat tgttgattcg atagaaatat atcttaaatc agaaggattt aaaatatata
    21121 aagcatatga tggaatgaaa gctttggaaa taataacaga gaatgacatt catctaatac
    21181 taatggatat aatgatgcct aaattagatg gaatcaaagc aactgtaaaa atacgagaag
    21241 aaagaaatat tccaataatt ttaatttcag caaaaagtga agatacagat aaaataatag
    21301 gattaaatat tggagctgat gattatataa caaagccatt taatctatta gagcttatag
    21361 ctagggttaa atcaaactta agacgatatg taactttagg taattatgaa gatacatgta
    21421 aagaaattct aaaaagtgga gctttggagt taaatacact aacaaaagaa gttaaaattg
    21481 atggtgaaaa cataaaaatg actccaattg agtataaaat aattgaactt cttttagaaa
    21541 ataaaggacg agttttctca atagatgaga tatacgaaaa agtatggaat gaggaaagtt
    21601 ttaattcaga aaatacagta gcagtacata tcagacgaat aagagaaaag attgaaataa
    21661 atccaaaaga accaagattt ttaaaggtgg tgtggggagt tggttataag attgaaaaat
    21721 tttagtggaa aaattataaa agaaaagagt ttaatattta attgcatttt gattttagtc
    21781 atttttacat ttacacaaat gttaggaatt ttaatatgtt ttaatttttt ctctgagagt
    21841 ttaatttact ctatggggat tatgcttttc ttaaacttta ttttatataa aatactgaca
    21901 atgtagatga ggtgggcaac ttggagaaat atagagtatt aaagttagtt tcattaatca
    21961 taatatctat ctcatttcca ttaactatat tgttggtgac aataggactt gctgagccta
    22021 aatacaatat acaaaaaact tctacaaaga gtgggatttt tgatatatct gatgattttt
    22081 atgatagtaa tatatttgac gaaggaacaa tggcaagtct attacccaag tttaagctat
    22141 ctgtaggtgg taaattaact agtaaagaaa aaggtaaatt ccaacaagaa ggtaaaagta
    22201 tagatttaag tagtagtgat tctgagtatg ataaaatcat gattaatgaa caagcttctg
    22261 aagaatattt aagttatcta aaaaatataa aagtgtatgt tattaataca tacacaggag
    22321 tattttatac aaatacgtca tatgctagtt tatatgattt taaacaaaaa actaagagct
    22381 attgtaatgt agagataata aataagatag gaaagagctc atatattaaa acaataaatg
    22441 gagaaaaatt tgaactgaat aatctgagtc tggaactaaa tgaagtagat gaaggttttg
    22501 aggcatatgt atcttttcca gaagagccaa ctatagaaga tggaatagta tacactaatt
    22561 ttcaaatatt taaacaagct acagaaaaag taagattatt ttttgtagct agtttaagtt
    22621 tagcaattat atgtttatta tctataattt tatatatcaa aataaaaggt gaagttttaa
    22681 aaagaaataa tgtattttta ctaatataca gtaagatacc tatggaattt aatgtaatat
    22741 tagtatctat ttcaattgca attttaacta tatatgctct tgctgtatct tatcatattg
    22801 atgtaattgc attagtttct ttatctttac tgatagtatc aaataatata ttttttataa
    22861 atgtgcaatt gagctattta gaaaataaaa tgtgtatatt taagacaagt attatagtaa
    22921 gagtgatttt atggttaata aaaactgtaa gggaggtcag taacgctata aagaaagtat
    22981 ctttagcaag gaaagttatt gttatagtga taatatcttt agctttaatc atggcaatta
    23041 gcactcgaag tataggtatg ggattactgt tttctatatg tattttttta ggatttacaa
    23101 tatatataac taaaagactt tcatatctta gttacgtaat agaaggtaca gaaagaataa
    23161 aaaagggaga attagattat aagataaaaa ttactgggaa tgataatttt acgtctttag
    23221 ctgaaaatat aaataatatt ggagaaggtc ttgatagagc tatagaagag caagtaaaaa
    23281 gtgaaagaat gaagtctgac cttataacaa atgtatctca tgatttgaaa actccactta
    23341 cttctataat aaattatgta gatttaatta aaaaagaaga atcaatacaa ccagagtata
    23401 taaatgatta tataaatgta cttgagtcaa agtcaaaaag actaaaatta ttgatagaag
    23461 atttatttga agcgagtaga gtaagtagtg gcaatataga attacaaatt agcaagattg
    23521 atttagtgca actattaaga caaagtatag gtgaacttga agaaaaatta tctaaaaata
    23581 atttatattt aaaattaaat gttccaaatg ataaggtgta tatatgggca gatggaagaa
    23641 gaatgtatag agtatttgaa aatcttttat ctaatatagc aaaatattcc ttagaagaaa
    23701 ctagagtcta tattgatgta tatgactatg gtgaaaatgt aaaggtaact atgaaaaata
    23761 tatcttctta tgaattaaat tttgacccaa gtgagattat ggaaagattt aaaagagctg
    23821 atgaatcaag gaatactgaa ggaagtggat tagggcttgc tattgcaaga gatttagtag
    23881 ctttacaagg tggaaaattt tatatagaaa tagatggaga tttatttaaa gcaaatttag
    23941 agtttcaaaa atatgaagaa gaaataacaa atatggaatg agatagtatt taagtatata
    24001 tattttttta ctgtcgaaag cttttattat aatatattag aatatttaca gtagagaatg
    24061 aagagtaaaa acagagtaac tttaagtcac tctgtttttt atttaaaatc aataatataa
    24121 caacttaaat taaaattgta cacatagttt taaaataact tatacaataa aacattatcc
    24181 aaatatcaca agataattcc aaataaatat atagatatca ctcctgtaat aatagaaata
    24241 ccaatagatt taaacttata tgcaacaaga agtacaatca taaaagatat aattttaggg
    24301 ttagctatag ataaatatag actatctcca ttaaaaaata catctttagc agttaaggaa
    24361 gtaagtattg ctacaggtat aaatttcatg atttttttca aaaaatcagg catctctttt
    24421 tttgaaaaaa ttaacatagg aagcactctt ggtagatatg taacaatgta cattccaatt
    24481 ataataaaaa atatataatt attattcata agattcctcc tttttacagt aagattcttc
    24541 tataaagaaa ccaattaaag atgctaaaat tgatgcaact attattacta aattgctttt
    24601 gaataatgca tataaaataa cagaaataat gattgatgat ataaatacta caatataaat
    24661 cttatttttt atttgagaaa ctattaaagc tataaacata gaagtcaata tgaagccaga
    24721 aatagaactg tctatagata tactttctcc taaaaatgct ccaataaaat tagctaaaac
    24781 tgatgaaatt aagcagaaga aattaagata aatagcattt ctatcagacc aatttccagc
    24841 agtaaatttt tcataattaa ctgcaaaagt ttcatctgtt atagtatgac aaaatggcaa
    24901 tataaatttt ggacttttat tttttatgta catgttcaaa ttagaactca ttagaaaatg
    24961 tcttaagtta actataaatg tagtcaaaac aatagatgtt acacttgcac cagtagaaat
    25021 cattgaagct gcaatgaatt gagaacttcc tccaaatact aaagttacca ttagtgctat
    25081 ttgaaaaggt gaaagaccag atttttgtaa tagtattcct cctactatac ctataggtat
    25141 ataacctaag aatataggaa ttgaagcaat aaagctttct tttaattgtt gagttctttc
    25201 cacaataaat cactcctttt gtattaaatg tattaaagta ttcgtaaaac agaaaaatag
    25261 attaattgta taattgcaat tataattaaa aataaatttg gattaatata taaaatacta
    25321 tacaacaaat agataatctt aaacggttat taaattttat ctatttgtta ttatgatgta
    25381 ataatacata ttaatctcta taagttaatt actatctggt gtaattttat tttaacaaca
    25441 aaaaaaaata cacacaatta aaatattgtg tgcaatacaa ttattttttc tcttctaata
    25501 gtctttttaa tacgctcaaa ccagctttaa gttcttctgt actttctgta gcacatacag
    25561 ctattcttat tgcagaaatt ggtttttctt ttccaacagc aaaacgttca gaagcataga
    25621 cctgtacacc ttctttaagt gcttgtatct caaatttttc tgccattatt ccatcaggta
    25681 gaatcaacca tctaaatata cattcttcat ttcccaaaag attatatcca gataaatatt
    25741 gattaataat cttgtttctt cttcttgcag atttacggcg tgcattaatt aatttatcgg
    25801 cttcacctga tgtaatcatg cgataagcaa tttctgttaa aaaataagat tgagatagat
    25861 taatgttgta taatgcgctt gataatgcct ctcgatactg tttaggtgta gagatatatg
    25921 ctagccgtaa actaggtgca ataatttttg ataaactcgt aatataaatt gtttgattgg
    25981 gcagatagga agccactgga tttaaatgtg tttcattaag taaactatga atagcatcct
    26041 caataacaat taaattgtat ttagatgcaa tatttgcaat catttttcgt ccattttgtg
    26101 acattatatg tgtagttgga ttttgataat ctggtattat gtatagacct ttaatatttt
    26161 catttttaca agcatataat agtccttctt cactaatctc attatcttct tgtttaattg
    26221 gaattagttg aatcccaagc attttagctg ctgtctttat tccaggataa gttaatgggt
    26281 ctacacctat tctatctcca tgttgaaaca aaccagctaa aatagcaaca attgcatttt
    26341 gtccaccact tgcaggaagt aagctatctg atgtagtttc aagcccagct ttataaatta
    26401 atttggcaat agcttctttt tgccatttag caccatctct ttgtccatat tggaatatgg
    26461 ttttaaaatc tatttcctta attatgtgtt taaacaaagt attcatttct tctagtgtga
    26521 aatctggatt cattgtgccc atttcaataa atgtaatttt attattactg gacatcaaga
    26581 atagatttga acgtgtatca taagatacaa aagttccact tcctgtaact ccacttatta
    26641 gacctttttt ttcacaaatt ttaaaagctc tagagatagt actcacatta acatctaaga
    26701 aatctgccaa ttcacgttgg ggtggtaatt tagtacctgg taataaaaat ccattgttga
    26761 tatcttgttc tagttgttct gcaagcgcct tatataatat ttgccctttt gaaggtctct
    26821 ttcgtttcca gttcatagga taattttcaa aagaattaat tggcataagt tttcacctca
    26881 cattattaat ttgatttttt ctttatctaa aacaataaat tctaaagata caaataaaaa
    26941 ctgataggaa ataattctat cagtttttgt cttttaattg atttcaaatc ttcctataat
    27001 ttttatacct tctttatcat aaagagggat tgttttttta aatatattaa aatttctttt
    27061 tcttgtatat aaaacagctt cttctggtgt ctttggttga ttatcacaat cgtacaaatc
    27121 tctttttttt acgtagccga cttttttacc tctacctatt gtttgtataa gttctggttc
    27181 aatggaattt ccatttgagt ctattatatg tgtaccatag gtttctccat ttttattata
    27241 attaatctta ccaatagtat attctacatc ttcattttgt ttaaaattgg agttgataga
    27301 aaatattgac cctattatta taaaggttaa taaaaactta agacctaaat taattttctt
    27361 tttatcttga ttaaacatag aatctaacct cttttttaaa ataatatttt ttttatttag
    27421 aaactgagat acgaatgatg aatacttcaa agatttttga tactttattg tatctaatat
    27481 tatatatgca tactctttaa tttcactcgt ggtacacttg tcaatcacaa tttcatcaca
    27541 agataattca cataattcat gaaaatattt ttttaataag tataaaattg gattgaacca
    27601 atatatgata caaattatac taattagaag cttaaataag ttatcttttc ttttataatg
    27661 aattaattca tgtttaaaga tgaatcttaa ctctttatta ttgtactttt tttctggaat
    27721 tattatttta cagcgtgtta aacctataat ggcaggagaa taaatacctt taaccttata
    27781 tatctgaagt tttttattta tacttagttc ttttgcttgt tcatctaaga tactagtaat
    27841 atctatttc
//
LOCUS       DAEHWO010000049        27274 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEHWO010000049 DAEHWO010000000
VERSION     DAEHWO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27274
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.049"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            17..838
                     /locus_tag="KNP54_002500"
     CDS             17..838
                     /locus_tag="KNP54_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007789443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBF0893377.1"
                     /translation="MSKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHIKGSFILDIDK
                     DLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGACRLFFQLKHLG
                     LKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPMEYVKSKLYKKD
                     TVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLKDIEFLKKFFK
                     DLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDNEIKTGQE"
     gene            complement(971..2584)
                     /gene="ggt"
                     /locus_tag="KNP54_002501"
     CDS             complement(971..2584)
                     /gene="ggt"
                     /locus_tag="KNP54_002501"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBF0893378.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2809..4746)
                     /locus_tag="KNP54_002502"
     CDS             complement(2809..4746)
                     /locus_tag="KNP54_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893379.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEVEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVAKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4733..5500)
                     /locus_tag="KNP54_002503"
     CDS             complement(4733..5500)
                     /locus_tag="KNP54_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893380.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5788..6462
                     /locus_tag="KNP54_002504"
     CDS             5788..6462
                     /locus_tag="KNP54_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893381.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6486..7490
                     /locus_tag="KNP54_002505"
     CDS             6486..7490
                     /locus_tag="KNP54_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0893382.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7602..8831
                     /locus_tag="KNP54_002506"
     CDS             7602..8831
                     /locus_tag="KNP54_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBF0893383.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALSSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8839..9513
                     /locus_tag="KNP54_002507"
     CDS             8839..9513
                     /locus_tag="KNP54_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893384.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9516..10748
                     /locus_tag="KNP54_002508"
     CDS             9516..10748
                     /locus_tag="KNP54_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893385.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11034..12299)
                     /locus_tag="KNP54_002509"
     CDS             complement(11034..12299)
                     /locus_tag="KNP54_002509"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBF0893386.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12352..13500)
                     /locus_tag="KNP54_002510"
     CDS             complement(12352..13500)
                     /locus_tag="KNP54_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBF0893387.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13591..14136)
                     /locus_tag="KNP54_002511"
     CDS             complement(13591..14136)
                     /locus_tag="KNP54_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBF0893388.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14359..15303)
                     /locus_tag="KNP54_002512"
     CDS             complement(14359..15303)
                     /locus_tag="KNP54_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBF0893389.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            15689..16570
                     /locus_tag="KNP54_002513"
     CDS             15689..16570
                     /locus_tag="KNP54_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBF0893390.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(16631..17839)
                     /locus_tag="KNP54_002514"
     CDS             complement(16631..17839)
                     /locus_tag="KNP54_002514"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBF0893391.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(17912..18164)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18316..19305)
                     /locus_tag="KNP54_002515"
     CDS             complement(18316..19305)
                     /locus_tag="KNP54_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBF0893392.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGLIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISLYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            19457..19897
                     /locus_tag="KNP54_002516"
     CDS             19457..19897
                     /locus_tag="KNP54_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0893393.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKN
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            20224..20451
                     /locus_tag="KNP54_002517"
     CDS             20224..20451
                     /locus_tag="KNP54_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBF0893394.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            20477..22597
                     /gene="feoB"
                     /locus_tag="KNP54_002518"
     CDS             20477..22597
                     /gene="feoB"
                     /locus_tag="KNP54_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBF0893395.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKNSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(22730..23548)
                     /locus_tag="KNP54_002519"
     CDS             complement(22730..23548)
                     /locus_tag="KNP54_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0893396.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            23755..24039
                     /locus_tag="KNP54_002520"
     CDS             23755..24039
                     /locus_tag="KNP54_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893397.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     gene            complement(25092..27185)
                     /locus_tag="KNP54_002521"
     CDS             complement(25092..27185)
                     /locus_tag="KNP54_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0893398.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVKNPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SVQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         9574 a         4161 c         3361 g        10178 t
ORIGIN      
        1 ttcagcaaaa gaacttatat caaaactaga aaaaaatgat aatctagttg taatagattg
       61 tagatttgat cttatcaata gaacttatgg tattgattct tataaaaaag gacacatcaa
      121 aggcagtttt atcttagata tagacaagga tttatcatct cctacaaaag aacatggtgg
      181 taaaaatcct ttacaagacc ctttaatact aaaagaaaaa ttagaaaaaa tgggtgttga
      241 taatgacact acgattgtaa cttatgatga tggagattta aatggagctt gcagattatt
      301 tttccaatta aaacatttgg ggcttaaaaa tgtctatgta ctagatgggg gaataacatc
      361 tttcgtaaag gaaggtggag aattggaaga gaaagtgaat ataccaagtt gtacaggtaa
      421 ggaaattaga ccaaatataa acaatgattt agttgttcca atggaatatg ttaaatctaa
      481 attatacaaa aaagatactg taataataga ttgccgtgct aatgagagat accagggttt
      541 agttgaacct gcttactcaa aagctggtca tataccaagt gcaaaaaatt atttttgtaa
      601 ggatttaata aaaagtgact ttgaaaatgg ctcacttaaa gatatagaat ttttaaaaaa
      661 attctttaaa gatttaaata attatgatga agtaatttta tcttgtggtt cagggatatc
      721 tgcttgtgtt aacagtcttg ctcttagaga actggatata cctcacaaga tttatattgg
      781 tagctttagt gactggatta gttatgatga caatgaaatc aaaactggtc aagaataagg
      841 ctcataatct atataaaatc agcatatgat agcttaaatt ttgtaaaggc gtcagtcatt
      901 gtagactttc gcctttactt attatttcat atactcttta aatttattat atatatttta
      961 gttgataata ttaataaact gcaatatgac catcacatct tgattccgtc ccacaaatat
     1021 aactttcctg ttctgtttta aatattattt gacctcgtcc catgtcgaca gtatcatgaa
     1081 ttacttttat ttcatgaccc ttttcaatta atgaatctat tatatgcttt ggcatctctg
     1141 gttcaacttc tatttctttt ccttttatcc actgccatct tggagcatct agcgcctctt
     1201 gtggatttaa tccaaaatca atcatatttg ttaacacttg aatatgtcct tgtggttgca
     1261 taaaagctcc cattacacca aatggaccta ttgctttatc ttctttacct aaaaatccag
     1321 gtattatagt atgataaggt tttttaaatg gttttactac attgtggtgt ttagggtcta
     1381 aattaaaatt atttcctcta ctatgtaaag caatcccagt tcttggtatc acaattcctg
     1441 aaccaaaatt tatgtaattg ctctgtatat atgaaaccat atttccatcc ttatctgcag
     1501 tacaaaggta tactgtacca ccacaatatg gctctcctgc agttggatac aaagcctctt
     1561 tattgtcaat caataaactt ctttttttag catactcttg gcttagtaat tcctgaatct
     1621 ttaccttcat atgctctata tcagttacat atgttttaga atctgcaaaa gctaatttta
     1681 aactctctat aattttatgt atgtcttcta cattttctat atttccttct aattccaatt
     1741 cttttaatat gttaagtgcc attaaaactg ttattccatg accatttggt gggatttcaa
     1801 atattttata tcccttatat tctgtactta taggttctac ccatgttgga taaaaacact
     1861 ctaagtcact ctttcttata gccccattaa attttttaga atattcatct attttatcag
     1921 caagtcttcc tctataaaag ctttcagcct gagtatttgc tatctcttct aatgtacttg
     1981 cctgttcttc acatataaat atatctccag cctctggagc tttaccatct ttagaaaatg
     2041 tatcaaacca tggtttgaac tcttctccaa taagttcttt ttcatagagt tcatatgatt
     2101 ttttccatac cttagctaca ttaggagata ctacgtatcc ctctcttgca tagtttatcg
     2161 ctggagataa gcattccatt aagctaagtt taccatattt tttatttaat tctgaccaag
     2221 ctgctggtat tccaggtaca gttactgctc caaacccata ttttggcatt tctttcatat
     2281 tattataatt ttttaattcc atattttctg gagcaaagcc actagaattt aaaccataca
     2341 atcgtttttc ttcctctatc caaacaaggg catatgcgtc tcctccaatc ccattgcttg
     2401 taggttctac tactgctaat gtggcggctg ttgcaactgc tgcatcaaca gcatttccac
     2461 ccttttttag tatttcaagt ccagcttgag atgctaatgg tgttgatgtt gcaactgctc
     2521 catttttagc atacacgaca tttcttattg atgagtattt atgttggtag gcattaaact
     2581 tcataaattt cagctcctcg tcatttttta tttgatattc tgcttagatt tattatataa
     2641 catcaagtaa tgtaactgat acaaaatgat ataaaatata gactttttcc taactttaat
     2701 tttgtcttta aataaatatc ttaaactcaa ttctagtatt ttctatctgc acttaaataa
     2761 gttattttat tcaaaacata tatctaattc ttttgactta aaaataattt attcttttat
     2821 catgtttaga gcatatttta aagttaaaaa ataatatata aaatatccta taaaataaat
     2881 gactagagtt atgataattg gtacaagtaa tgaccttggt ataaactttt gtgctataga
     2941 catagcaaat aaattatgaa ctgtacctac aactaatggc attaaaaata taacttttaa
     3001 ctgttttgat attattttct caatatcttt attatttgct ccaagtttta ttaacataat
     3061 atatctttcc ttatcatcat atatatttga taattgttta aataagatta tactacctgt
     3121 acataaaaga aatactacag acaaaaatat gcctataaac agcattagac cacttaattt
     3181 tatcaagtta ttataacttt caatacttga tgtaaaatta aaaggataag taaatttcat
     3241 attttcactt actatatttt ttaattttaa agtcaaatcc agttcttttt tttcattttt
     3301 tatatcaatt aatcttatta atctagaatt tccatgtaat tttaactgat taaatacgtc
     3361 atcttttgct acaattaaat caaacgtagc ttgtgaattt atttctggct ccaagatgct
     3421 tttttgtact ttaaacagat ttatatcata ctcatttgta tctttaatat gcaagtttat
     3481 tttttcaacc tcaaagtctt taaaaaatat ttttttgtat gaatcagaaa catagtacac
     3541 agattccttt gaagttaatt cttcataatt gttattctga tattgtctta attttttaaa
     3601 atcactttct ctaataatat ctacagacgt tctatcttct atataactat ttccattttt
     3661 ataatacatt tcaatattta tatctttgtc tataagttct attgttttat caaagattat
     3721 cttattatct tttttatatt tatataataa tttgtcaatt tcgttattta cataagaatt
     3781 tcctaaattt atggtataac tgtatttata attttcactt atgttcctat ctatatcgta
     3841 ataaagtgat atggtaaacc ctagcatagt tacacttgta gctattaata ttgctattac
     3901 agccaataca ctactattgc tctttaattt aaatccaagt tcagaaaatg caattaaatt
     3961 ctgtccctta taataaaaac tttttctctt cttaacagca tcaataatca tatacatcgt
     4021 tgatgaaaaa aataaaaaag ttccaggtat tattgtaact aatataaaaa ctgaaagcat
     4081 aatattttca gcaataaaat aactaattga cattaaataa gaaatagcta ttaataaaac
     4141 accaagtaca cattttaact ttataaattt tttaaactta tacttttctg gatatttatt
     4201 aaataactct ataattctct tatttctgat aactatagta tttcttattc caataactat
     4261 gaatattatt aaaaataccg ctagtgtctg aactaaggcc tttatactta agttcatatt
     4321 tactactatc atttcattca ttaattttac aagcatcata gtcataagct ttgaaaataa
     4381 cagtcctaaa aatataccta ttagtattgc aactataccc atcaaaaaag tttcatataa
     4441 aaatattttt cctatctgat ttttcctcat tccaagtaaa ctataagttc ctacttctcg
     4501 cctacgtcta ttgaaaaaaa atgagtttga ataatatata aataaaaata caaataccac
     4561 tattacaatt gaacttgtat taatactcat cctagttttc tctccaagtg aactcaacgc
     4621 ttcattatac tctatagatt taaaactaaa aaatacaaat acactaaata caattgaaat
     4681 aaagtacatt aaataattaa aaaaactatt ctttacattt tgcattgcaa ttctaaataa
     4741 agtcattttt attaactcct ccaattaagg aaactgtatt tactatttta ttatagaact
     4801 ctctgttact ttctcccttt acaatttctg tgaatattat tccatccttt ataaagagta
     4861 ttctattgca aaaactcgca cttatagcat catgagttac catcaatatt gttttattgc
     4921 tgtctttgtt taattttaat agacaattca acaaatccct agcagattta gaatctaatg
     4981 ctcctgtagg ctcatctgca agtactaatg atggttttgt tgctatagct ctacatacag
     5041 ctcctctttg cttttgtcca ccagaaactt cgccagggta tttatctaat atagattcta
     5101 tatttaattc ttttgaaatc tcttttattc tattttctat tactgatact ctttcatttt
     5161 ttaaagaaag aggcaacatt atattttctt ttattgtaag tgtatccaaa agattagaat
     5221 cttgaaatac aaagcctaga ttatcacgtc taaaatctgc caattcattt tgcttcattt
     5281 taatagtatt ctttccattt atataaatat ctcctgatga aggtaaatct attgtagaaa
     5341 taatatttaa aagtgttgat ttaccagcac cggaagaccc cataatacca acaaattctc
     5401 ctttataaac cttgaaagtt attcctctta gagcttcatg ttttgaacct tttcttccat
     5461 actccttttt tatattttca acagataata tttcttccat agttaataat cacctttcat
     5521 cacaattagt tatttatcaa ttctcacaaa tatattatat atattaaaat ggcttttaaa
     5581 catttaatta tattaattta aggttacatt ttcgtaagta ttaattatat ttcttcaaat
     5641 ttattgcaat tatgtttaaa atataattta tcaagtaaaa tatagttata ttaatataat
     5701 tattttaggt aataaggtag aaatatttta atttatcaag tagaatatag ttatgttaat
     5761 ataactattt tgaattagga ggtaagaatg tttaaaataa tggtagttga agatgacgtc
     5821 tcattgaaaa atatcatagc aaagtgtctt actaaatggg gacatgatgt tcatcaaata
     5881 gaaaatcttg aaaatataat agaagagttc aaaaactata acccagaatt agttttattg
     5941 gacataaacc ttccatttta tgatggtttt cattggtgta atgaaataag aaaaatttca
     6001 aaagttccta taatttttat ttcttcaaga aattctaata tggatgtaat aatgggtgta
     6061 aatttaggtg cagatgatta tatacaaaaa cctttttctg tagatgtctt agtagctaaa
     6121 gttaatgccc ttttaagaag aacttataat tttgttgata ataactcaaa tcagattatt
     6181 cacaatggtg ttactttaga tttatcaact gcaacaataa actatgaaga taatactatt
     6241 gagctaacaa aaaatgaaat caaaattctt catgagctta tgaaatataa ggggcagata
     6301 gtaagtagga ataaactcat gaaaaaatta tgggataatg attggtttgt agatgataat
     6361 acattaactg tcaatgtaaa tagaatacgc tcaaagttaa atgaaattgg tttagaagat
     6421 tttatagaaa caaaaagagg attgggttat ataatcagtt aaaacaattc taagtaggtg
     6481 aatttatgag ctttaaagat tttctcaagg ataaactagg ttttttagta tacaatttta
     6541 ctttcttaat ttttacagta tcagttatta tattttctcc tgtagatgtt tttctgactg
     6601 atactatttt atatatatta gttgtaaatg ttgtgttttt atttttatat ctatttatta
     6661 gctacatcaa gaagaacaaa tttttagata agataaaaaa tgatacattc aaaattaata
     6721 tgaatgatat agaattagct agatgtaaaa atgaagaaaa aatatacttg aacattatta
     6781 aaaatcatca atatcaatgt aataacataa taaataataa tatcgagaaa tttgaagaaa
     6841 acaaagagat tttaaatatg tgggtacatg atgtaaagat acctatagct ataataaaac
     6901 tcattcttga acaaaatgaa aatttaattg atgaaaaaat ttcagatgac atagatagtg
     6961 aaatatttag aattgaaaac tccgttgaaa aaattttata tttatcaaga ctcgaagatt
     7021 ttcataagga ttttttaatt caagaggtaa atattgaaaa aatcattaga aatattataa
     7081 aaaaatactc aaaatatttt atttcaaaaa aaattatttt agacttaaat aatttgaatt
     7141 ttaaggtttt atctgatgaa aaatggctat acttcatatt cgagcaatta ttgagtaatt
     7201 ccctaaaata ctcctcatta ggagataata tatctatcta ttgcaaaaga accaaaaatt
     7261 atttacaatt aagagtggaa gatactggtt gtggtataaa aaaggaagat ttaaatcgaa
     7321 tattcaataa gggatttaca ggtaataatg gaagaaacaa ttctaaatct acaggtcttg
     7381 ggctttattt agtaaaagaa ctttgtgata agcttggtca taaaattgat gtagattcag
     7441 agtacaacca atatacaaaa tttactatta cattcaaatg tgatttatag tatcttatta
     7501 ttgatagttt attttcatta acttatattc aacttcttat agtaattcta tatgtacatc
     7561 ccagtatata attaagtagt ttttataaaa aggaggaaga catgtctttt ctaaaaaaat
     7621 ttaaaaataa aagatttaga aataacagtt ttaaaagtaa caactttaga aatagcagtt
     7681 ttggaagtag tggcttcaag tctaaaaata aaggttttaa aaacaatccc tttaaaaata
     7741 agagattcaa aatatatgca ggaatagcag taatcatact tttaattcta ggagttcttg
     7801 cttatgttga ttcgaaaaac actgaattac aagctaatga aaattttatc gaaacatata
     7861 ctattcctga aaatgaaaaa atatttataa atgggatggt tgttcctaag caaactaagg
     7921 acttcaatat atctggagat tatgagttaa gtgatgttaa tgttacaaat ggtcaaaaag
     7981 taaatcaagg agaccttctt tttactgcta aaaatccaac tataatagca gaaatagata
     8041 gtttaaaatc acaacttagt caatacaaaa aacaaaaaat atcactttct gatattgctg
     8101 aaaataaaga tgctattgct tctataaatg cacagataac tgctttaagc tcccagatag
     8161 cttctctgga taaaaaagct tatgacagag ttactgctcc ttttgatggc acagtatact
     8221 tgaatgacca aactggaaat ccagaccaac cagtttcatt tatgactatt caaggtctag
     8281 agttttatat gaaaggacaa gcaagtgaac aagatttacc taaaatgaag attgaccaaa
     8341 tggtcaatat actagttttt tcaactgacc aaaagcttac tggtagaata agttttatat
     8401 ctgataaacc atctactcca aatactgaaa tgggagctca gcagaataca ctatcttatt
     8461 atgatataaa catagcattt gataatcaag aaggattagt aaatggattc catcttcaag
     8521 catcacttga agtagctaat tcaagcttta aaataccagc atcttgtgta cttaaagaca
     8581 acaaacactc atatgtattt aaggatttag atggtatatt gaaaaagcaa attgtagatg
     8641 tagcaagtca aaatgatgat tttgctgtag ttagaggcgg tcttgaacaa ggcgatataa
     8701 taataaaaca ccctactaaa gaaatgaaag aaggagaccc agttcaaggc gatggcgtaa
     8761 ctgctggttc taataatgga gatactactc caaacaaaaa agtagaagaa gttactatgg
     8821 atgtgaatta atttacatat gttaattaaa ttagaaaata ttcaaaaata ttacaaagta
     8881 gggaaagatg aattacatgt tttaaaatcc ttaaatttag aaattgaatc tggagaattt
     8941 gtcatgataa tgggtaagtc tggtagtggt aaaactactt tacttaatat cttaggtttt
     9001 ctagatgtat ttgatgaagg aagatatata tttgatggaa cagatgtaac taatttgagt
     9061 gaaaatgaac gttctgtttt tagaaatatt aatattggat ttgttttcca acaatttaat
     9121 ttaatagaaa ctctaaatgt atatcaaaat gtagagttgc ctctaattta caataaagca
     9181 ctaaaaaaat ctaatagaga agaaattgtt aaagataaat taagttctgt tgggcttttg
     9241 gacaagctta agcagaaacc acttcaatta tctggtggtc aacaacagcg tgtagccatt
     9301 gcacgttgcc tagcaaatga ccctcagata atctttgctg acgaaccgac tggggcatta
     9361 gatagtgaaa ctagcagaga aattatggag cttttaacaa ggctcaacaa acaaggtaag
     9421 actataataa tggttacaca tgatcaagat ttaactaagt atgcaactaa ggttatacga
     9481 cttaaagatg gtgtgtttac ttcggaggtg taatcatgag tttattaaaa aattctttgg
     9541 ccaatttaaa aggtcacaag cttcgtgtat ttgtagcttt actctggatt ataataggaa
     9601 taacttcagt aatacttgtt agttctatag gtaatggatt tcaaaaagaa attaagaaat
     9661 ctgtaaacaa tgtaaaccct aataaaacta ctatttcgtt tgaatcagcc gataacacag
     9721 gtcttactga tgatatgagt atttttttaa aaccatttaa tgcaaaagat ttagaagaat
     9781 tatcatttgt tgaaggagta gaaagaatag ctccttcaag agatgggttt aaccttgatt
     9841 cagtttactc ttcacaagca tcttttgata aaaaaactac gtatgttgat gttggaccag
     9901 taaaaaaaga ttctaaaata aatttaattt gtggtagaga tttttcttta gatgatgaaa
     9961 aaagaaaagt aattttactt acattacaaa gtacaagtga aatttttgaa aatccagaag
    10021 atgccttagg tcatggtatc aacataaatg gaactatatt tgaaataata ggggtattag
    10081 atgattctca gcaaaaccaa gctggaggat tctttggagg ttaccaagat atgcaattta
    10141 ctacttccct agtacctaaa aaggcttttg acactttaat gagtcaaaat tcttattcaa
    10201 atgaaattta ccagttagac ttagtttctt ctaaaggcta taatgtaaat gaagttgcaa
    10261 acaatgttat agctaaatta tatgagatgc accctggtat caatggttct tatactacac
    10321 cagacccaac tgaacagaca gcttatcttg aaagcattaa ttccaatgta aacaaatatg
    10381 tatctataat aactgtagtt gcaatgtttg ttggtggtat tggtgtaatg aatataatgt
    10441 atgtatctgt tatggaaaga caaagagaaa ttggtataag acgtgctatt ggagcaaaac
    10501 ctaggtctat attatttcaa tttttagttg aagctgtttt tataacagta tgtggtggaa
    10561 ttttaggaac tatagttgga tttactgcta ctaactatgt ttctaaatat ataggttttg
    10621 aagctatacc tagcttaaat agcttatttt atgcaattgt agctactata ttgactggag
    10681 ttgtatttgg tctgattcca gcctttaaag cctctaaact agaccctata aaggcaattt
    10741 ataagtagaa attgtataaa gattttcgat ttttagatta gtttatataa aacatactta
    10801 aatatataac gcactattat atatgataga ttaggaactt aatctttcca aatataatag
    10861 tgcgttcttt cataaaaagg attctcttcc ttactatatc taaattacca agatgttatg
    10921 ttctaattgt tcaaactaat acttccaatt ttgattaatc aatctcattc tcctaatata
    10981 caatctttta ctttcaatca ttgtacactc cgcctaaaaa aaataatctt aaattaggcg
    11041 ttatatacaa tctccccatt acatattgta taattaacct ttccatataa agatttacct
    11101 ttaaatggtg aattatcagc tttagaaaca aagctttcaa ctgtccattc ttcttctgga
    11161 ttgaatataa caatgtctgc tacagcccct tcttctataa atccaatatt taaattgtac
    11221 aactttgcag gatttataga cattttttct attaactgca tcatactaag atgattttta
    11281 tgcaccaaat ttgttattcc aagagctaaa gaagtttcaa gcccaataat tccacttgga
    11341 gcttttataa actctctatc tttttcttct ttactatgag gtgcatggtc cgttgctatt
    11401 atttcaatag taccatcatt taatccctct ataatcttat ctctgtccca tttacttctt
    11461 agaggtggat tcatttttgc atttgttcca aactccaata catcttcctc agtcaatgta
    11521 aagtgatgtg gtgaagcttc tgcaactaca tttgcaccta agtattttgc aaatctaacc
    11581 atatcaacag atacacctga acttatatgt tgtatatcaa ctttagcacc agtctttagt
    11641 gccaacatac aatctctggc taccataaca tcttctgcta cacttgatgc accttttaat
    11701 ccaagttctg aagctacctt tcctgcattt acacctggat ttccaactaa agaagggtct
    11761 tcttcatgaa aactaagtgg tacatccaac tcttttgcct taatcattgc ctccataatt
    11821 agattgctat ccattaaagg taatccatca tcagtaaacc ctggtacacc agctttttta
    11881 agagcttcca tatcaactaa ctctttacct tcaaaacctt tagttatagc tgctgcttgt
    11941 aaaacattta tacatgcatt ttttgacttt tctttaacat aattaaaagt atcttcatta
    12001 tctacaatag gattagtatt tgccatacat ataacagttg taaatccacc tctagcagca
    12061 gatttagctc cactttctat atcttcttta tatgtaaacc cagggtctct aaagtgtaca
    12121 tgtacatcca ctaaacctgg agcaactaca ttaccactag catctattat tttttcatat
    12181 tcatcacttt catcaaactt gcctatttta taaattttat tttcttttat aattaagtca
    12241 atattctcat ctctttgact tttagggtct attactctac catttttaat taaaatcata
    12301 ttatttctcc tttatatttt taatttatat agactcatat aatattatac attattttac
    12361 atacttaaat acaaaattac gtttgacatc aatagccttt ttaggacaaa gttcatggca
    12421 acagtaacat cttatacatt tacttaagtc tataatagca cccttagtcc ctatctctat
    12481 agtggatgca ggacaagctt ccttgcattt tccacatttt atgcaatctt gaaatcttac
    12541 cacaggcttt ggtgttataa gctttgaaat aggttcattt aaaaattttg gtagctttac
    12601 agaaaacaat cttaaatcct tacttacatt tggaatcttg taatttttta taattaaatc
    12661 ttttatatct tcacctaaaa tttcaatatc tgaaaaatct tcttgtatat atcctctctt
    12721 aatagcacct ctaattgtag caactctatt tggaagtaaa cttataatct tacatgcaac
    12781 aacatctata gcatatggat tttgtgatgc taataaaacg cctatttctc gagtagtacc
    12841 agctgaaggt ccatcacctt ccatacctac tataccatcc ataattgtca atgttggttt
    12901 tatataatca caaatatcta aaagtacatt ttcgcaaaac aactcttctg taggaaatct
    12961 ataatgtatc tctgcttttt tcaatccagc tatgcatcca tataagtttt ttgtaccacc
    13021 agtaaaagtt gccattatat gagtctttaa tttacaaaga tttattatat aatctgaatc
    13081 tactattggt ttaataatat ccatatattt tagaacatgt gctttttcac tatgtatctt
    13141 aacatctgaa acatcataat ttaacttaat gcccagttca tttgctactt cttcaattcc
    13201 agatgcctta taaatgctct taagagaact ttgattatat ggaccaccag ggctatctgc
    13261 tattgtaata tcacaattta actctaaaag tttttcacat acaactttta caaccatagg
    13321 atgtgtagtt gtagcttctt caggcttttt tttcattaat aaatttggtt ttataagtac
    13381 tttgcttcct tttttaacaa acttatctat accaccaata tcctctaaat ttttttcaat
    13441 agataacttt acttcttcat aattgtaagt tttacaactc ctaacagata ccgacttcat
    13501 attatctcca tccttctatc acaacagttt atttgtataa tttaaaaaag gagaaaccaa
    13561 agtttctcct tttaatctat gttttaatta ttattttcca aaatgtctgt ttaataatcc
    13621 taagaatgct ttaccatgtc tagcttcgtc tttacacatt tcatgtactg tatcatgtat
    13681 agcatctaat cctaattctt tagctctctt agctaatttt aattttccat cagttgcacc
    13741 atactcagca tcaactctaa ctcttaagtt ttcttttgta tctgcaacta caacttctcc
    13801 aagaagttct gcaaatttag cagcatgttc agcctcttca aaagctattc tcttatacgc
    13861 ttcagctact tctggataac cttctctatc agcttgtcta ctcattgcta aatacattcc
    13921 tacttctgta cactcaccag taaagttggc tcttaatcct tcgattattt ctgcatctac
    13981 accttgagct actcctattc tatgttcatc agcccaaacc atttcgcctt tcatttcttc
    14041 aaatttatca gctccaactt tacatactgg acattgtgct ggtgcagcat ctccttcatg
    14101 tatatatcca catactgtac aaacaaattt tttcataatt aatttcctcc caattttata
    14161 taattaaatt tttattttta agtttaataa cttgctacaa gaatatatat accccagact
    14221 ttatagctta aacactaaaa ataaaattta tttcctaatt aattttatca ctttgaaaca
    14281 ccagtatcaa ccaagttttg atgtcaaatt tctacataat acataattta tttgattaat
    14341 taggaaatag ttgtcatatt aaatactttc taatgaagac tcctctgaat ctttaagttt
    14401 cacttttttg ctctttaaaa aagataattt agtttctgca gttatgattg caacaaatat
    14461 caagatacta ccaataacca attttgctgt aataagctcc tttaaaatta ttatagaaaa
    14521 tattgtacca aatacagcct ctgtggataa tattatagct gttctagttc catcaactct
    14581 tttttgacat atagtctgaa ataaaaatcc aattgtagta ctaaatacag ctagatacat
    14641 agttcccatg taaccagata attcagcttc catctttaat tgacctgcaa atgtttgaac
    14701 tacaacagac attaaaaacg ctactgtaaa ttgaatagct gtcaatgcca ttgggttgtt
    14761 atcttttgca aactcacttg taaagaatat atgaaatgca aatccgaatg aacatataag
    14821 tgttagaaaa tctccaaaat taatagagaa atcagcttct aaagaaagta tcccaattcc
    14881 tataagagct accaaactac ttattattcc tattttatca agttttcttc tataaagtat
    14941 aaatcctatg aatggaacta ttacaacatt agctgctgtt ataaacgcat ttttagatgg
    15001 tgtagtgtac ataagtccaa tagtttgtac tgtgaatgct agaaataaaa atattcctaa
    15061 aatccctcct gcttttaata attttttacc catattagca cgaatctgtt taaaaaacag
    15121 taaattcata attatagctg ccaagaaaaa tcttaaagtt atgatttgta gaggtgtaag
    15181 cccaccgtct aatgcaaatt gggttgctac aaagccactt ccccatataa ttgctataaa
    15241 tattagtcct atttctccaa agtatttttt caataaagcc ccctcctttt tatttttttg
    15301 caaaattata aaccccctaa acagcaagag agtttttcta taagcattac tataaattaa
    15361 tatagtaaat tttttcagta ttttaaatct aaatttacat acattttgag ctcaaattta
    15421 tatccactat ttaacagtaa tatattaatc attttttgta aacacctttt taataaattt
    15481 ttatattttt tatatttttt tacctatact aaattttttt atagatattt ttaatatata
    15541 tgatacttta atattatgca aataatgtca tataagttac actttagtta tcttagttac
    15601 aactttgtcg gtttactttt tctactttct tcgatataat tataatatat ttttgataca
    15661 attcgacaaa agggggaatg ctgtaattat ggtaaaaaaa agaaaaaaga aaactgttac
    15721 acttactata cttgttgtaa tagttattgg tattttttct atggcatggg cggacatgtc
    15781 tagaaaaaaa gaaatgaaag aaactcaaga aagacttaaa gctgaaagat tagaaaaaga
    15841 aagaattgaa aaagaaaaaa atgaacctat tattggtgca aaaaaagaag ctgtaaaaga
    15901 atatggatat gacgcaaaaa tagtttggga caaacttaac aaatacgact attcaaacaa
    15961 tggagaaaag atagtctttc ttacatttga tgatggacca tctactacta atactccaca
    16021 agttctagat atcttgaaaa gacatggtgt tagaggaact ttctttatta agggtgattc
    16081 tcttgaaaga aaaggagcta atgaaatttt aaaaagaaca tttgacgaag gaaatgcaat
    16141 agcccatcac tcttatactc atgactataa aaaactatat cctaacagaa gcctaaatct
    16201 cgatacattc gtaaatgaac ttaacaaaac tgatgaagct atgaaaaaag tcttaggaaa
    16261 gaatttttcc tcaaatgtag ttagatgccc aggcgggtat atgtcatgga aaaatatgga
    16321 acctctagga aactacttaa aagagaaaaa catggcatca attgattgga acgctttaaa
    16381 tgctgatgca gaaggtaaaa agaaaaatgc acaagaatta tttgaacatg caaagaaatc
    16441 ttctgaaggc aaagaaatgg ttgttctttt aatgcatgat acttatggaa aacaagaaac
    16501 agtaaatgca ttggaccaaa ttataacata ttttaaagac aatggttatc aatttaaaat
    16561 tttaatataa taaaaaagca agtttattga atgtacattt tatactcaat agacttgctt
    16621 ttactttact ctattttact agctcgattt ttacaaattt tttctttcct atttgaacaa
    16681 ctaattcact ctcttttaca atagtgctta aatcctctac tttttcacca tttaccttta
    16741 ctccaccttg agaagctaat cttctaactt cactcttact cttaacaatc tcattagaaa
    16801 ctagtacttc gattaagtca aatccatctt ccttaacttg aattgtttgt atatcttcag
    16861 gtatttgacc tttttggaat acagatttaa atctttcttc agcttcttta gcagattctt
    16921 ctccatggta taatgttact atttctcttg ctaagttcat ctttatatct cttggattta
    16981 ctgaaccctc tttcaactgt gattctattt tattaacttc atcaggatga acatctgtca
    17041 ctaaattgta gtatttaatt ataagttcat caggaatttc catagatttt tggtacatta
    17101 ttcccgcttc ttcatctatt ccaatatagt tacctaaact cttactcatt ttttctttac
    17161 catctaatcc ttctattaaa ggcatcatta ttactatttg agactccata ccaaattctc
    17221 tttgtaatga tcttcccatt agtaaattga atctttggtc agttccacca agttctatat
    17281 cagcttctaa tgctatagag tcatatgctt gcattaatgg gtagaagaac tcatgtactg
    17341 atattggcat ttgtccttca tatctctttt taaaatcttc tctttctaac attctcgcaa
    17401 cagtaatagt tgctgctaat tttattacat cttcaaaatt taacttagct aaccactcgc
    17461 tattaaatct tacaatagtt ttttctttat ctaaaacttt gaaaatttgt tcttcataag
    17521 tttttgcatt tgcaagaact tgctctgttg ttaaagcttt tctagcttta gattttccag
    17581 ttgggtctcc aatttttcct gtaaaatctc caattattat tactatttga tgacctaaat
    17641 cttgtaattg tttcatcttt ctaagaacta ctgtatgccc taaatgtata tctggagcac
    17701 ttgggtctag acccaatttt actatcatag gctttccttc tttttctgat ttaataagct
    17761 tttcccttaa ctctttctca tctattaaat catctacacc tttcataatt attcgcattt
    17821 gctcgtctat cgatttcatt tttcattcct cctaaaatat ttatataatc tataattttt
    17881 atttttataa taaaaaaagc tttcatcctc ttaaaaggac gaaagcattg cttacgtgtt
    17941 accaccttag ttcatcaata tctcacgata ttaatctctt agagtacaat tacatatact
    18001 cgtgtactat aacgtgtact aatccgatat ctcttaatgg ttgttatctt tcagagatag
    18061 tgctctgaga tgtattcaaa ctaaatcaat ttattccatt tcaccaaact ggaactctct
    18121 gttaaataaa atctagccct acttcttctc ttcatagcat ttatatattc agattatttc
    18181 atcaattaca agaaattttt cttaacttac tcataatata ttattatttt tatattttgt
    18241 caaccttttt tattattata tacatgtttt tttacattat actacttttt tatatttttt
    18301 accaataccc aaaatttatt tttcaatcaa aagatttatt tgtttattga ctatattact
    18361 ctgactcaat cttatattta ttttcttatt taaaaatgcg tttataatta ttaaaccaat
    18421 aactgttaca tcaaatataa aaaacagcaa taaaattatt atcaaaaata aaattctagc
    18481 atataataat tttctaaact tagctattat aaagttttgt agtgacatac atgagtctct
    18541 aatgataaaa tagagactta tataggttat tgatataaag attgttttta aataaacaga
    18601 atcaacttta acattcaaca gttttagaac ttcaaaaatg gctagataag aaacacatat
    18661 gtaaaaagct ttttttgagc aacataaaaa ttggtttaaa cttctaaaat tcttaaatat
    18721 taaaaatttt tttagagaat tagaatctaa aatatgcaat ttattcccta aaattaaact
    18781 taataaatat atgcaaaaca ccataccaaa aggaaacaat gctatcatta aataataaat
    18841 aaaatttgta tacccattaa aataaatcca tttgctatat ccttgaaatt ctttcataaa
    18901 actataacct attaatgttg aagcatatat atcaataaaa accattacaa taagcccaaa
    18961 tactgaacca tatactaaat catccataac cattgtaggc ttatttatta gatagccaca
    19021 cattatacca agtaatacac tctgacttgc ccaaatagca gttcctagat ttccaagtac
    19081 cagagaaatt attaaaagcg aagtaattcc agataaaatg gtatacttta aatcacattt
    19141 caagcagatt atacaaaaaa atactggcac tataaaatct aagtaaatag catatccaaa
    19201 tccagtactc acagctataa ttgttactac tatgaataaa gatgacaata aagctgcttc
    19261 agttaatttt ttagtagtat tcaaaacact gcctccataa atcataaatt ttctaactaa
    19321 agttttgttt ttaatatagt atatcacttt ttaaaaatat ttttaataaa tataaatttt
    19381 aataaaggta tttatgttaa aaatggtata atgtatctta atattcagtt ttttaagatg
    19441 ctaggaggta attactatgt ttaaaattaa acactttaat gatttgagtt tagatgaatt
    19501 ttatgaaata gcaaaatcaa gatatgaggt atttgcttgt gaacagaaga tattttcatt
    19561 aaacgattat gatgatatag ataaaaactc ttatcacata tttttaaaag aaaatggatt
    19621 gatttgtgct tacgctagaa taattcctaa agaatacagc tcttataatg atgtttccat
    19681 tggtagagtt ttagttcttt ctagtcatag aagaaaagga ttagcaaaac aaatgatgga
    19741 ttgtgctata gattttataa aagttaactt acacgaaaat aatataacct tatcagcaca
    19801 aacttatata aagaaccttt acttatcttg tggttttaaa gaaatctcag aagtatacga
    19861 cgaagcaggt attgaacata ttaaaatgag attatagtgt tgacaagcta atattgttaa
    19921 tatataattt aagtataaat taaatattga attgatattt aggtatttga aaatacctta
    19981 catagagtca gaaggctttt gctttctgac ttttttatta tcaaaattca ataattatat
    20041 ggattcaaag tgttaatttt tattctatat tctactttcc ccaaaagtaa gaattatacc
    20101 caactttgta tgataggcat cttgcctatc ttttttttgt aaaagtaaca aggtaataat
    20161 ataatgcata gtttaaaata agaagattag cccaggctaa atttcaagca tggaggtgct
    20221 attatgaaaa accttaacga tattcaagtg aaaaaaactg tcaaagttga agatatatta
    20281 tctagtggta atttaagaga aagaatgtta gcgcttggtc ttactagagg agctgttata
    20341 gatgtagtta gaaaaggtcc aaaaaataat ttaactgtct ataaaatcag aggtagcaag
    20401 atagctctac gacaagaaga aagtagctta atattagttt ctgacattta aaaatttcta
    20461 gcaggaggat attaatatgg ggttgacaca taactcaact aaaatgagtt ctttaaaaga
    20521 catgtttgat atagacaata aggaagacca gtttgtaatt gcattggctg gcaatccaaa
    20581 tacaggtaaa agtactgtat ttaatcatct tacaggactt agacagcata ctggaaactg
    20641 gccaggaaaa actgtagcta cagctcgtgg taattttaaa tataaaaata ccgaatatgc
    20701 attaatagat ttaccaggaa catattcttt atttgcctta tcacaagaag aaattgtagc
    20761 tcgtgatttt atatgttttg gtaatccaga tgcagtaata gtagtatgtg atgctacatg
    20821 tcttgaaaga aatttaaatt tagtatttca agtgatggaa cttacagata aagttatttt
    20881 gtgtattaat ttaatagatg aagctagaaa aaaaggcatt actattgata aaaaactttt
    20941 agaggattct cttggtattc cagttatttt aactgctgca agaaatggct ctggtatgga
    21001 tgaactattg gatactttaa atgatgtatc ttttgacaaa tataaattaa ataataaacc
    21061 tgttagatac aatgaaaata tagagaatgt ggtaaaatca attcaaccag aattggataa
    21121 tattatacca ggtataaatt ctagatggtt gggacttaga cttattgatg gcgatgaaag
    21181 tatatttgaa tctatgagta attatataga caaaaattct atagatgcta ttaatgaagt
    21241 aaagaaaaag attccagaca atataaataa acagaaaata agagatgagt ttactaaaat
    21301 caactatgat tatgctaaaa aactgagtga tgagtgttgt tctaatgttg ctaaaaaatc
    21361 aactgataga gaagaaaaag tagataaaat attaacatct aaaatatttg ggcttccaat
    21421 aatgctctta ttattaggta ctatattgtg gattactata gaaggagcta actatccatc
    21481 cactttatta tctaatttat tactcggatt tgagccaagt atttcgggta tattaaatag
    21541 tattaattgt ccatcatggt taaatgatat gttggtttta ggattataca gaacattagc
    21601 atgggtaatc tctgtaatgc tacctcctat ggcaatattt tttccattat ttaccctact
    21661 tgaggatttt ggatatttgc caagagttgc atttaactta gaccacctat ttaaaaaagc
    21721 ttgtgcacat ggaaaacagt gtttgactat gtgtatggga tttggatgta atgcagctgg
    21781 agttattggt tgtaggataa ttgactctcc aagggaaaga cttatagcta tacttacaaa
    21841 caactttgtt ccttgtaatg gtcgttttcc tactttgata gctatatcta caatattttt
    21901 tagctcagtt ataaccaact ctttcgtatc aagcgtagca actgcacttt gcataacttt
    21961 actgataatt ctaggtgtta taataacatt gttggtttct tacactcttt ctaagacgct
    22021 attaaaagga gttccgtcta catttacatt agaacttcct ccttatagag ttcctcaaat
    22081 aggaagaact ttatatacct ctataataga tagaacaata tttgttttag gaagggctgt
    22141 aatggtagcc atacctgctg gtgtcataac ttggatattt gcaaatatat atataggaga
    22201 tttaagtata ttatcacatg ttgcaaactt tttagaccct ttagctaaat taattggtct
    22261 tgatggtttt atattacttg cttttattct tggattccca gcaaatgaga tagttgtacc
    22321 tatactttta atggcttacc tagcaactgg ttctatgata gaattagata gctttagtgc
    22381 tttaggtcaa gttcttagag aacatggatg gacttatttg acagctttaa atgttatgct
    22441 gttcagttta ctgcattggc cttgtgcaac aacactttta acaataaaaa aagaaactgg
    22501 tagtttaaaa tggactgcct taggattctt aatgcctact atacttgctt ttgttgtttg
    22561 ttttttaaca actacagttt acaatttatt tatataatta gtattaactg acagtagaca
    22621 tatattagag aaaccattta aaaatttata tactttatta taaagcatag agatatattc
    22681 aatgataagt aaaattactt aacatttgaa tatatctcta ttttaattct tatctggata
    22741 cttggattga aatttcagtc atataattat cttcattact ttcacaaaaa aagtcaagta
    22801 tactctcctc atacgaattt ccaacaattt tatattcatt ttcatatata tattttttca
    22861 atttttcgta agatttatat gaatcctcat attttccaat atgttttatg caagcataca
    22921 ttccttctgg ctttacatat agctttttat cctttatttt tttatctatc ttcaaataaa
    22981 aacttgatat acttaaatag tccccatttt ttatattttc attacttact attactccca
    23041 actcatatcc ttgatacaaa tttttcgatt tacaataatt ggtaaaatct attaattcca
    23101 tcataaaatc actattactc atattactca aatcgcttga tagaactaaa tattcttcaa
    23161 actttttgga tatataaatt tcttcactat tcattttaga aattccttca actgttatat
    23221 ttattctatt ttgcatctta gaacttatct ttcttagttt ttttattttt tctcttatct
    23281 ttttttcttc ttctttaagc attttcacac aaagctgggg agttctattt tgtatatact
    23341 cttttatttc ctctaaactc attcctattt ctcttaatga ttgtaatata tcaagtgtat
    23401 catattgata aactgagtaa tatctataat tatttttatc tttatattca ggagaaaaaa
    23461 tacctatttt gtcatagaaa attaatgtct gcttagatat accacacaat ttagcaaatt
    23521 cacctgttgt aaaatactgt ttttccaagg gttatacact ccttttcttt ttgttgtcta
    23581 tatagttact atattcttta ttatttacta aatcaagtag ttattatttt agaaaatcaa
    23641 tatggttttg attttaaagc ttaaatatca gttagatgtc agttataaat attttaccct
    23701 ttcccatcat aaaaaagata tcccctctta acttttggat ggaatattat atttatactt
    23761 gttagagtga aaattgtaat aggtgctaca ataagatatt taattaaaca taaagttaat
    23821 tattgtaata aaaaatcttt agataaatta gagttaaagt acggaaatat agatagagaa
    23881 aaagctgtta aactagaaat attttatcag tatttaatag aacttgaata tatagaaatg
    23941 agtttattaa taagaagatt agatactgca ataacatcat tagcattagt atctattata
    24001 acaatagcat catattattt aatcagaaaa aatgtgtaat tatgtaagct atttataata
    24061 aaacactgat aaaattaata ataaaaaggt aataggattt ctatactacc tttttgtttt
    24121 tataatatag tgtaatttta ttatattttt gtatgctaat gtaactagat aatcataaga
    24181 taacacatta aaagaaaatt atgaaaactt acattctgta tagttaatat aaaacataag
    24241 taatataaat ttatgtaaag caacaaaaga tagatttaca ttccatatag ttaatataaa
    24301 accttagaga aagcgaaaac gtaccattaa aatcaaatat ttacattcca tatagttaat
    24361 ataaaacgtt gtaatcatag ttccaattag ccactttaac atgcatttac attccatata
    24421 gttaatataa aacaccaaaa taaacttagt attttcaaca cttacacgta tacaactctc
    24481 ctaaatttgc agtgaacgag caatagtgca attgataacg cttatcatgc actctcaacg
    24541 ccttatattt caactgttac gccaaatttt ttcacaaata tcgctcactg caaaattcct
    24601 ataattttat tatatcataa atatattact tttgaatatt gataccaatt tataccataa
    24661 taaaagcaaa aaaacgtaat ctatctacat tagatttaaa ttctataact taaagttttt
    24721 tacataatat ttatgcttgt ttaatcaatc taatatatca ttcttgtata ttgcttttaa
    24781 tagtcttttt tcttaaataa atatctatct gaacaagcat agtttaatta aaaacttttg
    24841 tattccctta aaactgtatc tacctcttat tattttattt atgatatatt atttttaatc
    24901 taaaaataga tatctatttt tattatggtt atcccttttt aaaatacttt aatcatatac
    24961 tattcccaat ttaacatcca ttgaaatgct attttcttat attgcaattt ataattgata
    25021 tatcttcaat ataataattt aatgtatttt tgattttaaa gcttttcagt gatattattg
    25081 ataaattaga attaattatc tagctttaaa aggtcaaaga tttctgttgc tgtctgcggt
    25141 tttccaaata aatatccttg tatgtaatct ggctttattt gtttaactaa atcatactct
    25201 tcttgtgttt ctacaccttc taaacatact tttattccta catcatgaca aattgcaaca
    25261 ataaaatgta taaatgtagc atcaaactta ctctttaata tatctttaac aaatactcta
    25321 tcaattttca ctatatctat tggagaaaat tttaaaactt ctagagacga gtatccagta
    25381 ccaaaatcat ccatagcaat ataaattcct aaatcttgta aagccttaaa tttaaactgt
    25441 aaaatactca tattttgtac tgtatgactt tctgtcaatt ctaaaacaag attttgataa
    25501 ggaaaatttt catcatctat aatttttact atatcttcaa taaatgtgtc ttctaatatt
    25561 tgaacagctg aaacgtttac actcacttta aaaaaaggat agtaatcaat ccatttccta
    25621 aaagtacgta atgccattcg aagcacccaa gcccctacaa tatttatcat atcattttct
    25681 tctaatattg gaataaattc caaaggagaa attgctttgc atttgtcatt agtccacctt
    25741 aaaagaactt ctacacctat tattttatga ctttctgtat ctacttgtgg ctggaatcga
    25801 agactaaacc ccctaaaatc atcattaatt gatgccttta aatcccgcat catttctaat
    25861 gaatacattt tattttttaa tatttcttgg gagaaaaaaa caagcctgtt tttaccatgc
    25921 tctttcgcat attgtaaaga gtaactagca cacttataaa gttcttttac tgtatctcca
    25981 tgttttggat atattacaca accagcagaa attgttatat ttaatccata ttttctccat
    26041 agttgaaggt gtataatcat attctgtatt tgattatata gagttagaat ttcattttct
    26101 tcaacattat caacaagaat gcccatttcg tccccatcaa gtttataaag ttcagcatta
    26161 tctggtaaaa tagattgtac agactgtgct agtgttttta ttatattatc tccaaaatcc
    26221 ctatcataca tctcattaac atttttaaaa tcgtcaatat ctaataatac tatgcataat
    26281 ttttcaatca taggatttga aattttatct tcaaatacac tcataaattc atgataattc
    26341 agtaactgtg tcaatgaatc aatcttattt tgtttaccta attgcgtcat tattcctgca
    26401 aaaatacttg gctctccaaa ttcatcacgc attagttgac ctctacatct taaccatata
    26461 tattctccac tacgattttt agccctaaat tccactgtat gataatccat ctggttttta
    26521 cctatttcag tgtttgactt ataaaaacga ttccagtctt ctggatgtac aatttttttc
    26581 cagtaaacaa gcggattttt aacaatttct cctggtaagt caaataattc aacttgtgat
    26641 ggtgaatatc gaaatacgcc tgttttcata ttgcaaatgt atatatattc atctgtacct
    26701 ctaatcaaag catcgtaaag caatgtagaa ttataatcaa aattgtctct tgaaaaatta
    26761 aaaactcctt tttcttcttt attatttgat atttcatgaa attcattaat cttaattggt
    26821 ttatttaagc ttgttgagtt tgcaatatct attgattgat gcatatgaac aactgtgcca
    26881 tcttgccatg taattaaact atcataattt tcaaaaacac gatttaactt attacatttt
    26941 tcataccact ttattaatac tcctttttta tcattcttta ataattctaa aactttacaa
    27001 aaactacaag tagaattttt ttcaggatat aatacttgcc aacaaacttt tccttctgga
    27061 tctaaaatat tatattcttc tttcattttt ttgttcataa aaataatttc attagtatga
    27121 atatttgtaa catatatatt aatctgtagt tgatttaata taacttcaaa attatgtttg
    27181 ttcatatact tatctcctcc atagttactg ctctttataa caacattgtt aaaattattc
    27241 tttttagaag atttacttat aacttataca tata
//
LOCUS       DAEHWO010000050        27223 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEHWO010000050 DAEHWO010000000
VERSION     DAEHWO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27223
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.050"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(68..928)
                     /locus_tag="KNP54_002522"
     CDS             complement(68..928)
                     /locus_tag="KNP54_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBF0893399.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEIEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(1245..2573)
                     /locus_tag="KNP54_002523"
     CDS             complement(1245..2573)
                     /locus_tag="KNP54_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBF0893400.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(2721..3050)
                     /locus_tag="KNP54_002524"
     CDS             complement(2721..3050)
                     /locus_tag="KNP54_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBF0893401.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(3074..4363)
                     /locus_tag="KNP54_002525"
     CDS             complement(3074..4363)
                     /locus_tag="KNP54_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0893402.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(4379..4705)
                     /locus_tag="KNP54_002526"
     CDS             complement(4379..4705)
                     /locus_tag="KNP54_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0893403.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(4840..5469)
                     /locus_tag="KNP54_002527"
     CDS             complement(4840..5469)
                     /locus_tag="KNP54_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893404.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(5684..8341)
                     /locus_tag="KNP54_002528"
     CDS             complement(5684..8341)
                     /locus_tag="KNP54_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893405.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(8700..9644)
                     /locus_tag="KNP54_002529"
     CDS             complement(8700..9644)
                     /locus_tag="KNP54_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893406.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIDVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(9637..10662)
                     /locus_tag="KNP54_002530"
     CDS             complement(9637..10662)
                     /locus_tag="KNP54_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893407.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(10737..12305)
                     /locus_tag="KNP54_002531"
     CDS             complement(10737..12305)
                     /locus_tag="KNP54_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0893408.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(12418..13329)
                     /locus_tag="KNP54_002532"
     CDS             complement(12418..13329)
                     /locus_tag="KNP54_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893409.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(13313..14299)
                     /locus_tag="KNP54_002533"
     CDS             complement(13313..14299)
                     /locus_tag="KNP54_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893410.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            14659..15060
                     /locus_tag="KNP54_002534"
     CDS             14659..15060
                     /locus_tag="KNP54_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBF0893411.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            15063..15461
                     /locus_tag="KNP54_002535"
     CDS             15063..15461
                     /locus_tag="KNP54_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBF0893412.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(15911..16135)
                     /locus_tag="KNP54_002536"
     CDS             complement(15911..16135)
                     /locus_tag="KNP54_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBF0893413.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGVTMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(16170..17537)
                     /locus_tag="KNP54_002537"
     CDS             complement(16170..17537)
                     /locus_tag="KNP54_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0893414.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(17621..19156)
                     /locus_tag="KNP54_002538"
     CDS             complement(17621..19156)
                     /locus_tag="KNP54_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893415.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EVSLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGMTYK
                     IDCDVILVNLFELIMNNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(19179..19613)
                     /locus_tag="KNP54_002539"
     CDS             complement(19179..19613)
                     /locus_tag="KNP54_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893416.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(19873..20784)
                     /locus_tag="KNP54_002540"
     CDS             complement(19873..20784)
                     /locus_tag="KNP54_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBF0893417.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            21080..21433
                     /locus_tag="KNP54_002541"
     CDS             21080..21433
                     /locus_tag="KNP54_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBF0893418.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(21652..22593)
                     /locus_tag="KNP54_002542"
     CDS             complement(21652..22593)
                     /locus_tag="KNP54_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBF0893419.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(22694..23929)
                     /locus_tag="KNP54_002543"
     CDS             complement(22694..23929)
                     /locus_tag="KNP54_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBF0893420.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            complement(23973..24827)
                     /locus_tag="KNP54_002544"
     CDS             complement(23973..24827)
                     /locus_tag="KNP54_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893421.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(24955..26130)
                     /locus_tag="KNP54_002545"
     CDS             complement(24955..26130)
                     /locus_tag="KNP54_002545"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBF0893422.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(26229..27113)
                     /locus_tag="KNP54_002546"
     CDS             complement(26229..27113)
                     /locus_tag="KNP54_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBF0893423.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
BASE COUNT         8686 a         4862 c         2791 g        10884 t
ORIGIN      
        1 aaattattat cttatacaat gaatttgtat tatataataa gtatttttag gattctgtta
       61 cataatatta tttaaatatt cttctatatt tctcttcttc ttcttcagta aacacattaa
      121 atacaacttt taaatttttt tcaggatttt cttttagcca tagtctaact ctacttacag
      181 caagattagc tgcctctttt tttggataac caaatacacc tgtagaaatt ccacaaaaaa
      241 caatattttt tatttcatca atttctttta ttgtatttaa acatgattta taacaatgaa
      301 gcagttgctt ttcttgctct ttacttggct gaccaccaga tacaataggt ccaacagtat
      361 gtactacaaa ttttgcaggt aaacaataac ctctagttat cttagcatct ccagtatatt
      421 ctaaatgccc ttgttttttt attattttgt cacaatcttc tctaagtcta ggacctgcgc
      481 atgaatgtat ctcattatcc acgcatagat gtaatggttg taaacaccct aataacttgt
      541 tatttgcagc atttactatt gcatctgctc ttaaattcgt tatattacct ctccatatgg
      601 caatcccttc ctctatttct tctatatcat ttacatctac taactctctt tcttcacatt
      661 caatcaacaa taaattatgt aacatattaa gtatctctgg agcaatttct tttggtggat
      721 atacattcaa aagtcctcta agtatatctc taggcttaat ttcatcattt gataaattgt
      781 atattttaga aggaacttct tttgaaaaat atgcaattaa agtgtttata ttttttcttc
      841 tttgttcgtc agttagaggc ttgatagttt tatcaaaatc ctcaaataaa tttacatcat
      901 cagcataatc tctccacttc atagccatct ctccattctt gtattttaga cttaaaaata
      961 attatgtatt tatgtacata tttatttatt tctataaaca cctacataaa tcctgttaaa
     1021 agtgtaaatt ttttattatg caacttctct ggttatttct attgattgat agtaaattat
     1081 tgtacctaaa tttaatccaa ctaacaagta actaaaccta ctttcctaac tgcaaaatac
     1141 actatgtttg ccacttgtat ctcatttgta aataaataaa gtccctacaa atacattaac
     1201 taggctatgt actaaactgt aggaacttta aaaatatatt attcttaatt aagttttggc
     1261 caataatttt tatttgcttc tattaaatca tctagtaatt cttttgcaac tgttgcacta
     1321 ggaactgtct tagatagcat aagtgcttgc cacaatttat tataagactt ctcaatccaa
     1381 gcatcaacta ctaatttttc aactgctaat tgttgttcta ttaaaccttt ttggaatgtt
     1441 ggtattttcc ctattgataa tggttcatac ccgtcttttc caactataca tggaatttca
     1501 accatagcat catcttgtat attttctata gctccattat tttgaactat caataacata
     1561 cgctcctgtg tattaaaagc tagagctgta gctaaatcca ctataaactc tgcatgtatt
     1621 cctatcttaa gcccactgcc cttagaatgt ccttgctttt ctatcaatgc acatgaacca
     1681 aaaacttctt tttctcttcc atcaataact tcattggcac gagtataatt tacatcagaa
     1741 tgatttacaa cataatctgg aaatagatag tactttaagt aactacttgg tattgtagtt
     1801 aaatctgttt ttactatttc tttagtaaat aaattagttt caaaccaact atctttcttg
     1861 tcatttttca ttccttcttc accatttata aaaccatatt cttttatatg ttctactaat
     1921 tttggtaaaa gttcatttcc ttttttatct ttaattgaag tataccaacc aaagtggttt
     1981 aatccaaagt atcttatatc catatgttta cgagatttga gtcctgcaat ccttgctata
     2041 ttatgttcca tacctattgg catatcacaa atatttatta ccctagaatt aggtctcaac
     2101 cttctaacag cttccgctat tattgatgct ggattagaat aatttaacat ccaacaattt
     2161 ggagaatact tttccatata atctatgttt tcaagaacac cttctataga cctcattcca
     2221 taagctattc cacctggtcc acaagtttct tgaccaacta ccccatgttt tagaggtatc
     2281 ttttcatcta gttctctcat ttcaagtttt ccaactctta tatgagctaa acaaaaatct
     2341 acatctgtat aagcctcttt agggcatgtt gttgctaaat actctatatt agggtccttt
     2401 tcctttatta gtatttcaca agctttagct accttatttt gtctttcttc atcattatca
     2461 tataatttga ttgctcttaa tggtaaccta tctaagttat ctagcaacat taatatgatt
     2521 tctggggtat atgtacttcc tcctccagct attactactg aaaatttttc cataataata
     2581 tctccttttc tatttaaaaa tttactgtat ttataaataa atttataaat actagtactt
     2641 taaagtaaaa gggagttcat ttattaaatc tattgattta ataaactata gccaaacttc
     2701 aagcactatt tacaagaaat ttaattctta ttaattcttg ggtccatcat ctcaaatata
     2761 tctacaagtt cagatactaa agaatgagca aataatgcat ttgaataatg gtcttcagag
     2821 tgcacaacta aaaaatcagt cccactatct tcactattca tagcatttga tagtaattct
     2881 aaatgatgct ttgatgctgt ttgtattttc tctgaggctg aatttaaaag gtgttttgct
     2941 ttattgtagt cacctttttt tatttcctta agagacatca ttacatcact tttagcatct
     3001 cctgcttctg atattatact aaatactttt tcttccattt caggtaccat atccttctcc
     3061 ttctaatgac ttgttaaaaa tcaaagctat catcatctaa tgttgtagct aattctgcat
     3121 ttttatttaa ttcttccttc tccattatct taaagaatgg ataatatatc aaggtcataa
     3181 gtattatact tgcaaatact aatacgattg ccttccaatc taatgtcatc aaaaatgctg
     3241 caacccctgg aggtaaaaag cctggtggtt ctgcaatagg taatcctact aatcctactt
     3301 ttaatgccat aaaattaagt gctccaacca atacaggtcc aaatacaaat ggtacaaaca
     3361 tatatgggtt cataactatt ggtgttccaa atattaccgg ctcatttatt ccaaatagtg
     3421 atggtaaaat cacaactttt cccatactat taaaactctt acacttactt cttgacataa
     3481 ggtacactaa tcccaaagtt atccctgaac cagttacttg caagaaacca tagtaaaaac
     3541 ctattgtaaa cacatatttt gggtctcctc ctgctgctat taacgttgca ttttctgcca
     3601 tatatgtagc tgctattggc atccatatac ttgaagttat tgctgctcca tgaagcccaa
     3661 agaaccataa taattgagtt ataaatagta ttatagttac tgcaaaaaca ttatctacac
     3721 tgcttatagc tggtgctaag aaattcatta taatagctgg taatggttga cctgagacat
     3781 ttttagttat tgctgctatt gctgtaaata acattataca tactatcatt ggagttaagt
     3841 ttctaaaact tttatttact acactaggta cttcttttgg aaatctaatt acgagatttt
     3901 tatcattcat aaacttagta atatcaacta ctaaaagtgc tactaatata cttacaaata
     3961 aaccttgtgc atctaaataa cttgtatcta atacaccatc tactacttgt ccacatacaa
     4021 caagttgtgc aacaactgct gtcataccta tttctacatg attaagatta tattttttag
     4081 ctagtgcctg agctataaaa aatgctgaat atatagataa taaactcata gtaaatttat
     4141 tagggataag taatgtatcc atattttcag ataataatgt ttttgcactt ccttcaggta
     4201 acatattgtt taatgccata aataacatac ttaaagaacc aacaattatt attggggtaa
     4261 tgcttatcat accttctttt atagcttgaa gatgcctttg tttttcaatc ttttgtgcta
     4321 ttggaagaag aaatcttctt aaattatttt gaagtgcttc catttttatt ccccccaatt
     4381 atctattttt atataattcg attgccgact tcataacaga aggagcatcc atacgaccat
     4441 aatgcttagt atctattaaa ccaactgcta ttttgtaatt cttacaagct tcaactacat
     4501 catcttcctt aaacctaatt tgtggtgcta caagtactac atcggtatca ttagcttcaa
     4561 tgtatgattt taaattttca aatgatgttg cctctatatt tatagtttta gtttttaact
     4621 tttcatgctc actacaaaaa cttttcatct tttccacaag tacacctgtt gaagctccat
     4681 ttgcacatac taataaaata ttcataatta ccctcctaca atatctaacc tcttttattt
     4741 tctaattttt tatcagccaa ttcttactct aattcctatc agtttttact ttaattctta
     4801 ttattttatt ttaattctta ttaatattta ctctaattct tagtactgcc aatgattaaa
     4861 cttgaaagcc gtatctataa cttcttcttg cttatatttt tctaatattt ttaagtatct
     4921 ttctttataa tcattatcta cttctttttc tggtattact atactagctt catttaaaaa
     4981 gtggaatgaa tcccttccca tttctaatcc tctatatgta tgcttgtcaa gtgccacgtc
     5041 cataacttct ggaactttac ccattgcaaa tccttttata attatatttt ttaataaatc
     5101 acttgatcta tctttctcac atgcacaaag atatcttatt gcatgtatga aaaataaagg
     5161 tctgtctcca tctgcatatg aatattcctt tcttacttga tttaaattat ttatgattat
     5221 tacagctgat gggtccccca ttcctatatc ttcaactgat attgtaagta tccttctcca
     5281 tagcttatct tctaattctg gtgatgatat atatagttca taagcaaatt cacaagcttc
     5341 ttccaccata tttcttctta tagctttttg aaatgacgat attatttcat ctgcactaaa
     5401 tccgtttctt gtagtcattc ttgcccatgg gtcatttgcc tttttatctc ttaatatttt
     5461 atcttgcata ttatttactc ctttttattt aaattttaat tatttatatt actcatttaa
     5521 taatataagc aagtattatg ccagtttttt tagacacttt aaaacactgt tatttcaatc
     5581 atttttatca tcaaaactta gatactttgt ctaagtatat ttatatgtgt ctaatattaa
     5641 tattatttta gactaaaaaa aattaccaaa taagttttta tactcattgg taatcttttt
     5701 cgattatttc tgcatattct aatattaata atatttgata gcactctttt tcattaattt
     5761 ctatattata ttttttatct aattgagata ctatatcttt tattttgctt aggctcttgt
     5821 gataatcaag tgttttttct ttatcaagct tttcaatttc tctagtattt ccaatcaatc
     5881 catctaccat gaaagctaaa tgcatcataa gtccaattac tttatcgtat ttcttttcta
     5941 tattaaatac taaaaacaat tcatcagaca catattttat atctttaaat atcctattat
     6001 aattagagct ttttaaggat gtctttaaac cttcaactac atcatcataa cctatactta
     6061 tctttataat attttttaat ttattgatat tttcatcctt atctatatct tttttgctaa
     6121 tatagtcaat tcctctaata ttaattcttt gttcattgat tactgcaaca atattactac
     6181 tttctttaag tttcgtaata tttaaactta aatctttttc tgttttatat gggacagata
     6241 taatatctat tccatctaag tacctactca tcttttcttc taatattttt cttgttttat
     6301 tatctacacc ttctgaaaca tgtgatgcta taataattgt tttagacaga ttttctttat
     6361 tttgaatttc attagttcca aaatagtact ttctcgtgtt agttatagag ttgtatacgt
     6421 catttaaagg taatcccata ttggccttct gaactgcttc taacacagtt aatgttgtca
     6481 ccataggaat tactcttact ccacactttt tttctttctt tataatttca tcaaaagagt
     6541 ttaatgaacc catatctgta aatagtaata catctttatt gtctatatta ttaattaaat
     6601 ttttaaaatc tacaataact tcatcatagc ttttatctaa cttcatatcg aaagaaatag
     6661 cactgcactt tccaataata tcaccaactg cttttaccat actacttgct gtagtttctc
     6721 catgcatagc aactataata ttaatgttat tcactatttt attttgttca tcttgtttag
     6781 cttgtactat gaataatgta atatatgcta cagtttctat agataaaaat aaatcaaatt
     6841 cattttcaat tattccaact atttttagtg ctgttttaaa ttcacttctg ttatttcttc
     6901 taatttgatt caaatctatg ttgtttgtag agctactttt atccaatacg ctttttatat
     6961 aaattgccat tgacttaaat attgattcac ttatgtctat ttcttcatct tctttaataa
     7021 tttgtcttat tgattcacac atgcttttaa acttaacatt attaaataga gaagcatctg
     7081 ctatattcat ttctacagat ttattaagat tagtatttac tgcattaata atatttatat
     7141 cattgtagtt aataacttct tcttctccta atgacgtaaa tacaaaatat tctattccat
     7201 gtgttataac ttcatctgct ttaatagact tctctctata atcatcactc acttcattta
     7261 tagatttatc aaaatatttt ttctctatat aaactggttc tttattatct cttttatatc
     7321 ttaggtatcc atttgcaaca gctaatttta tatcattttg aagttgacct acattatttt
     7381 tacaatcata aagtaatagt gatttaatta tttctttatg tacttttatt gaaatagaaa
     7441 tactttttga ttcttccttg aaaaaatttt tgactaattc cattctttca atcattgtcc
     7501 tatctctcag tgatggtatt tctattttca ttggtattct tctattgaat gtatctaata
     7561 gtgttgatgt cggattttct gtagtagcac atattattaa taccttagac tctctttctt
     7621 tcgttgcatc tcctagtctt ttaaatgttc ccttatctat aaaagtaaac aacatttctt
     7681 gaccttctgc tggtagtcta tgaatttcat ctaaaaatag tatccctcca tttgcaattt
     7741 ccaaaagacc ttttctggaa gattctgcac ctgtataagc tccttgttct accccaaaaa
     7801 tatgtcccat aagtaattgt gcattattag cataatcagc acaattaaat gttacaaaag
     7861 gagctttatt ttttctaatt ccactatcta tagaataatc gtacatatat ctagcaatca
     7921 tactctttcc tactcctgtt tctccataga taatagtatg aagtccattt gtaggataga
     7981 gcattgcgac cttgcatttt tctattatag gtcttaaact atgttcttta cctattagtg
     8041 tttcaaaact atcttttttt attttgtttt ctacttttgt tccttttttt atgccaagca
     8101 actcactttg tgtatcaagc aattcattct tgttaaggtt aagatttgca gggatataat
     8161 acacaggtct tccttttatc ttcgtaacca taccctcatt gaataattgg tttaaatatg
     8221 tacttatatt gtttcttgca attcctgtct tttctgataa ttggttagct gtaatccctt
     8281 tttcattttc cctatatgat gattctaaaa ctttcattac tttatctttt ttatatatca
     8341 ttacaagctc ccctacatta tagtatttta ttaactaaaa cccctataca cactttattt
     8401 tttaataaac tcttattctt taactaaggt tataatttat caaactttcc ttactttaaa
     8461 ttatagaaaa ttattgtaga aaaaataaga ttattgctca ttttttctac attactattt
     8521 ttaattttat agtactttct taacaacata ctttacttgt ttttaatttt attatatttg
     8581 aatttattat atttgaaaag tagaaataaa aaaccctatt ttggagtagt tttaaaattt
     8641 ctccaaaaat agggttttag tttgtatttc aaataaatac ctgttcaagt atttttatac
     8701 taaacaactt ttaaattttg ttgatattta tttatttctg atttagaaga atatacaaaa
     8761 tgtccatctg aaacatcaat ccaacttaat gacttttcat ttgaacaatc atatccatta
     8821 gaattatact ctattctatt tcttgactta gcatatctag ggtcaggaac aggaattgca
     8881 gaaagtagtg attttgtata tggatgaata ggattattat acaattcatt tgaatctgcc
     8941 aattctacta attttccatt atacataact cctatacggt cactaatatg tctcaccata
     9001 gataaatcat gagctataaa taaacaagtt aaattctttt cttgttgcaa ttttttaaat
     9061 aaatttacta tttgtgcttg tatagacaca tccaaagaag ctataggctc atcagctatt
     9121 ataaattctg ggtctactga aagagctcgt gctatgccaa tacgctgtct ttgtccacct
     9181 gaaaaatcag atggatactt atttgcataa cttctatcaa gtcctactag ctttagcatc
     9241 tcatatactt tattcattct atctgtttta tttttacaga taccttgaat ttttagtggc
     9301 tctgaaatta tatctgcaat tgtcatacgt ggatttaatg atgaagtaga atcttgaaaa
     9361 ataatctgca tacttttgtt tacatctttt tttataaatt tgtacgtttt tttatctgat
     9421 atgcaatttc ctttgtaaat tacttctcca ccagtagatt catgtagtct tattatagtt
     9481 ttaccagttg tagattttcc tgaacccgac tctcctacca atccaaatat ctcaccctta
     9541 tatatatcaa aacttatatc atcaactgct tttacagtag tacttttgtc caaatgaaaa
     9601 tattgcttta agttttttat ttccagtatt ttttctctat tcattagaaa tcacccttcc
     9661 acaatttact ctaactggta catctacttc aggtgcatct gggtgcaata accaagttgc
     9721 tgcactatgt gtatcattaa ttttaaacat tggtggctct ttttcataat ctatcttaag
     9781 tgcattttta ttccttattg caaaagcatc tccttttggt gggttcaata aatttggagg
     9841 cattccaggt atattatata aatagtcatc ctgcgaatct aaagtaggta atgaacccaa
     9901 caacccccaa gtatatggat gtctagggtc ataaaatata tcctctacag ttcctatttc
     9961 tacaatcttt cctgcataca taactgctat tctatcagct atagttgcaa ctactcctaa
    10021 atcatgagtt ataaatatta ttgacaaacc tattttatgt tgtaaatcct ttattaaatc
    10081 aattatttga gcttgtatag ttacatctaa agcagttgta ggttcatcag caatcaatac
    10141 atctggatta caagcaagtg ctatagctat tactatacgt tgtctcattc cacctgaaaa
    10201 atgatgtgga aattgtttaa atcttttctc aggattatca attccaacca attcaataag
    10261 ctctatggct ctcttttttg cctcactttt acttatacct tgatgaatga ttacagcttc
    10321 tgcaatttgc tttcctattg atatagttgg attgagagat gtcatagggt cttgaaatat
    10381 cattgatata ttctttcctc ttatatcttc catctctttt tcagacttct taaccaaatc
    10441 acttgattta agtaaaacct ctccattttt aatatatcca ttgtatggga gtatcctcat
    10501 caaactctta cacagtacag atttcccaca accagattct ccaactatag ccaatgtctc
    10561 accttttttt agattaaaag atacatttct tacagcctga acttctcctt cttctacttt
    10621 aaaacttaca gatagattat taacctccaa taaatgttcc aaaaaccatc aacccctatg
    10681 ctattcaaac cttagggata tatttttatc cctaaggttt ctaattaatt tcagtattat
    10741 tcaattgtcc agtcagctat gttccagaat atacctacac catgatgacc taaaactgta
    10801 tcaggtgtta atccttttat gtttggtttt ccaacatata ttgcatctat ataagcaata
    10861 aatgtataag gcatatcctt agtcatttct acttggaatt gtttatataa ctttaatttt
    10921 tcatctttat cttctgtttc tcttgctttt tgaagtattt tatctatagt aggattagag
    10981 taagcactgt aatttgcacc tttatctgtt ccaaatactt tatatgtatg gtcatctggg
    11041 tcaaatggac ttccccaacc tattaaatga gcatcttgat tagcccaatc tgtttcagtt
    11101 acaacaacag ctttagcatc aacaccaatt tcttttaact gttgtgcaca tattttagcc
    11161 atatcaactc taacttggtc actctcacct gctgttatct cgaaagctaa cttagtacct
    11221 tctttttcat agattccatc agaacctaat ttccaaccta gcttttcaat ttcttgttta
    11281 gctttttctg gattatattc aaacttttct atatcaggat tattatatgg tcccatttgt
    11341 aaaggtgaat atgctggtac accatgtcct aataatacac tgtcaactat tgcttttcta
    11401 tctattgcat agcttaaagc atttggtaat cctttagctt ttttatcttt aaagaattta
    11461 gaattaaaat tgtataatat acctctatag tcggctgttt tcattatatt tactttaaaa
    11521 ttcttttcgt ctttttcaaa gttagacata tctttaggag ttatttgagc taggtctaat
    11581 tctcctgatt ttaattgcat tgccttagcc ttatcatctg gaacaatctt aaagactact
    11641 ttatctaatc ctggttcttt tacaaaataa tcactattct taacaagtgt tatactttga
    11701 cctttgtccc atttttcaag tttaaatggt ccagtaccta ttggtttttg attaaattca
    11761 tcagtagcta tatccttacc ttccaaagca tgttttggta atactcctac tgttaaataa
    11821 tcaagcattg ctgtatttgg agcttttaaa gtaattttta tagtattatc attaaccaca
    11881 tcaatttttg ttatatcttc ataatttgat gctatctcag aagcattatc tggattcatt
    11941 atagtttcta ttgtaaactt aacatcattt gctgtaaatt tttctccatc atgccactta
    12001 acatcatctc ttaaattaaa agtatatgta tttgttgcct catcaaattt ccagtccttt
    12061 gctagacaag gaaccacctt attattttca tcatgagctg ttaatccatt aaatattaac
    12121 gaatttattt ctccatgttc atatagtgca ggatttatac ttgtatagtc attacttcca
    12181 taaacaagca cctttccatc tttaggcgta tctgccttct tatctttgtc tcctccacta
    12241 gaacaacctg ccattagact aagtatcatt actaaactta aaacttttaa cttctttaat
    12301 ttcatgatgc tccccctttt gctttttata aaatattttt caaagctttg accccattta
    12361 tttaaataga tatttcaaat acctcagtat ttgcttattt aatactcaaa tgctgattta
    12421 taaattacta gattttttat tattattctt tcttatataa ttacctatat ttgttataca
    12481 caccaatgtg gtaaccaaaa atatacccgg aatcagtata atccaccatc tatttgaaag
    12541 taatgcttcc tctgacaaag ataacatact tccccaagaa acaatttcta ttggtaaacc
    12601 aattcctaaa aagctaagtg tcgattcagt accaatagct gcgcctatgt ttgttacaac
    12661 catgaacatt attgatgcca caaaatttgg aagtaaatgt tgctttaata catagaagaa
    12721 tcctcctccc atgctcttag ctgctagtat gtattcgcta ttttttattt gtctaacttc
    12781 tgttctcact atcttagata tattcatcca acttgttatc cctattacta tggacataga
    12841 tactggattt gaatttccaa gtatagcttg tacaaatatt ataattaata ttgaaggtat
    12901 actaagtatg atttctgtaa acctcatcat tgcatcatct acaagttcag atgctgaacc
    12961 acttatacta ccataaacaa ttcctataac agttgatatt acagtggaaa atagtcctat
    13021 aaataaagat atttttcctc cataccatat catagaatat atatctctac ccattgagtc
    13081 tgttccaaat aaaaaagttt tatttggagc taaattagaa cttgctaaat ccatgtatgt
    13141 tggttcatgt gtcattataa aagatgagaa tacacttcca atgactatga ttgataaaat
    13201 aataattgat atatatggta attctttaat ttttttagat aaggttttct ttgtttctat
    13261 atgttcatct tctgctacta aaatataatt ttctcctaca atttcaaaat cactatattg
    13321 tggcttcatt agtatcacct ctatcatatt tcattctagg gtctatttta ttgtttataa
    13381 tttgagctaa catattccca aatactacta aagcccctgt tattaagcat aaaactaata
    13441 acatattata atcatgatac tttgcacttt caaaacaaag tgttcctaac ccaggataag
    13501 aaaaaacttt ttcaactaca taagttcctc ctagtatatg aggtatcgaa atggccatta
    13561 tactaatata tgatggcatt atatttctca ggcaatgctt aaaaacaata gttctattat
    13621 ttaaaccttt tgctttacat aaaagcacat aatcttctct tatttcctct agtaatttat
    13681 ttcttatcat atatgtgtaa taccatagat ggcttaatat aagtactgta agaggtaaga
    13741 ttagatgtga tatcctactt aatatactgg actcttctcc cattgaataa gcaccactac
    13801 ttggaagtat acttaagttt atactaaata taagtatgag tactaaggca acccaaaatg
    13861 atggaataca gttggttatt gttcctaatt tgcatatgat tctatcaatg agcttatctt
    13921 catgtaatgt acaaaatatt cctaacaata aggctagcac aaaggtaagt atatatcctg
    13981 aaccacctaa tattatagtg tttatataga catcatttat aacagaagta acattttgtt
    14041 tatatttaaa tgaaattcca aattcccctt ttgatgcatt tgaaatccat tttatatatt
    14101 gactgtatat tggttcatcc aaaccaagtt ttttcatagc attttctttt tcttgtgtac
    14161 tcattctttc tactccatcc ccatagtaag agattaatgg gtctcctgga gcaagtcttg
    14221 ccatgtaaaa aacaataaaa gataataaaa acattactaa aataaactgc aacaactttt
    14281 tcagtatatc ctttaacaaa ccccaacccc cctttgttgc aataaaaaaa accacataaa
    14341 agcaaacgta aagtaacgtt aaaaccttcg tggttccatt atcattaaac aaaattaaat
    14401 tttctatatt tatctatgag ttaattttag catcatttat taactgtgta aacaaacttt
    14461 ttaaaaattg ttaaaatttc atcaaattat tttatttata cctaaaataa aatttttata
    14521 ttctattctt cattattttc tataaaatta taaaatttta ggttgactat ataagaaaag
    14581 tatattatat tagtttgtat gcaaaccatt taagaggtga ttttattgaa aagtaattat
    14641 gactgtttta gaatagccat gctcttaaaa gaactttatt ctaaaactat gtacacagta
    14701 gaagaaaatt ttaaagaaaa tggattaaca caccaacaga ttatagttat aaaactgata
    14761 gctcataatc aagaacttac aatatcacaa ctatgtgatg aaatgtcttt agctaaaggt
    14821 acggtttcag gcataatcag cagattagaa cagattggat atatagaaaa attcaagaaa
    14881 tctaatgata aaagaaatac atacgttaag tttacaacaa caggatttga atttgccaca
    14941 aattttaaaa ttaaaatgca agaaagtttt gatgatattt ttaaaaattg tgatgaaaac
    15001 gaattgagtg acttagtaaa aaatcttaga aatatattgg caaaagtaaa ggagagataa
    15061 ttatgaatta taaattaata cttgcaatag tatttataac atcagcttta attttctaca
    15121 ctataggtgt atttggagaa agaaaggcaa aaattttaaa aaagaaacat gtaattatat
    15181 tttggcttgg ttttatattt gatactttag gaacatttac aatgagtaac atagccaaca
    15241 gccatacttt tgaagtaaaa tctgctttat cacaaaacct tcatagtatt acaggtcttc
    15301 ttgcaattgt gcttatgctt tttcatgcaa gttgggctac ttttgtccta tacaaagatg
    15361 atgaggaaaa gaaaaaattc tttcataagt ttagtatagt tgtatggact atatggttag
    15421 ttccatattt tataggtatg tttattggta tggctggata gtaaaataaa aagtgtgtaa
    15481 gaaatactgt aggtaaattt gtataagaca aatttatcta catccttctt tcacactttt
    15541 acatatttat ttataatact ccattatttc tttcatgttt cttaatacct atatagaata
    15601 tttaattgtt tctatagtat tttattattt tctcacactt tttcatatat atattgtttt
    15661 actatttctt catatgtata tatgaaatat tccattattt ctataaatgt tttattatct
    15721 ttctcatact ttttcatata tatattgctt cactattttt tcttatttct tcatatacat
    15781 atgaaatatt tcattatttc tataatgttt tattatcttt ctcatacttt ttcatatata
    15841 ttgcttcact atttttttta cttctttatt aaatacttat gtataacata catttaataa
    15901 acgctaacta ttaaacacct aatacttgag ttactcctgg aacttcactc accaaaacat
    15961 tttcaataat agctttgatt gtcatagtca ctcctggaca cccactacat gccccttgta
    16021 gtctaactaa aaccacacca ttttcattta catctataag ctctacatct ccaccatctc
    16081 tttgtaatac tggttttatc ttttcctcaa gcactttttc aactttttct ctcatagcta
    16141 ttccccccag aaatatttta ttagcaaaat tataccaatg gtttaaattt ttgtccatct
    16201 aatgatttat caaattcaat ttttgcttca tcaataattt tagtatccat aaatacatca
    16261 taagcactac aagccagtac tttagctgaa tttatcatag cagaaaatcc tatatttgaa
    16321 cctgctgatg aacatgactg ccatgtatga cttgcaattc caacaggcca agctgccatt
    16381 gcaaattgag ccactggtat tacataactt acatctccaa catcagtaga accagctagt
    16441 cctttatctt tgtcaccgtc aactatttcc ttgtgtatat agctttctac aatagattta
    16501 tcattttgta atgatgttgc tacacctaat ctttcttctc tagtaagagt atcacacaac
    16561 ttttttgcaa attcttcttc ttcaggagta tttttagggc aaccaacaaa aaccatattg
    16621 tcataaacta aatcagtcaa acattggttt ggtatatagt catatattcc atctgtaacc
    16681 ttatactcca tttcagtttc tgtcatcatt gctgctcctt gagctacttt tattaatcta
    16741 tcaagaacgt gttctgcatc ctttgctttt ttacctctaa taaagtacca actttcagca
    16801 aatccaggaa ctacattagg tcttccacca ccattagtta taacatagtg cattcttata
    16861 gagtcaataa catgttctct caaataatta gctccaacat tcataatttc aacagcatca
    16921 agtgcgcttc taccattatg aggagcttga gctgcatggg ctgttatccc tttaaattta
    16981 aattttacag ataagtttgc cagacttcca cctctccaag gtgcatttat atcaaaagga
    17041 tgccatgtaa atgcacaatc tacatcatca aaacagccat ttatacacat aactgtcttt
    17101 cctccacctt cttcttcagc aggacaacca aaatatttta ttgttccatt aaatttattt
    17161 tcttctatta atttttttat agaaacaact gctcctacac ctgctacacc caacaggttg
    17221 tgcccacatc catgtccagc ttttccttct accaatggct ttctttctgc acttacacat
    17281 tgtgatagct ctggtaaagc atcatattct ccaagtatgc caatcacagg tttaccctct
    17341 ccaaaacttg ctataaatcc agtaggtaaa ttttctactt cttcaatttt aaatcctttt
    17401 gactttaggt attctttttg aatgctactt gcatactttt cttcaaaggc taattctgga
    17461 ttttcccata ttttcttaga taaatcaatt aattcttctc ttatttcttc aacattattt
    17521 atgatatact ctttcataat tttcctccaa atatatgtat ttttgatatg ctttacagat
    17581 tatattatat actaacattc tatttattca caattttttg ttaattaatt ttattcatat
    17641 gctcttctat ggagtatatc ttatcttcac tttgcctctt cataaattta atgtactcta
    17701 tcttccataa agtagtttca gttttctcat ttaacataaa ttctaatata ttaatttctc
    17761 tcattctaat atcttcataa aatactacac tacccaatat tgccaattct aattcactta
    17821 atgatgcaaa caacattaaa tactcttctc caaataaaca ttcagattca agaatatcga
    17881 taaagtcttt tttagcattg atattttcct ttattattct tattttttca attatagatg
    17941 tactatctaa tatctcattg aatatctctc taaacgattc atcatccaat ttactttcat
    18001 catcaacaat ataatcttct aagtgttcct ttttattttt actcacagtt accatacttt
    18061 taaaagtgtt actttttatt gagcttagca cagattcaat aaatatcttt tcatattttt
    18121 taatatatct tattacatct tcatcttcta tgcttaatct ttttattaat acttcaattg
    18181 cttccataag tagtaaagtt atttttttat ttattctaat ttctctgtta atttcttcaa
    18241 aatcattata atccaaatta ctatctactt cagtgttaaa actatcatct acttcaatca
    18301 attcaattat attactttct tcagagtcta taactttatc ttcagtaata ttattgtaca
    18361 tatttttaaa ttgtttttct aaaaattcat actcatattt tgaaatttct aaattagtca
    18421 cttcatttcc taaaatagta gaaaaaatac aattattcat aataagttca aataaattta
    18481 caagtataac atcacaatct attttataag tcatcccata gtcataaaat aatttttctc
    18541 tatctttttt cttaaatagg ttacaaaatc tattttctat atctatactc tcaatataat
    18601 tcttcacata ataaataccc ttaacatcca tatcatctag tgccaatgga taatctatac
    18661 ttactggaac gtcctgagct tcaaatttta caatataact tttaaagaaa cttgataact
    18721 ccatcaaggt atcattatat gctattgaat tagtatccaa ttttctactc atcattagtt
    18781 tataaaaatc ttttagccta actaactctt cctctaatat ttcaatgcct ccaaggtaca
    18841 cttttttaac attcttagca gtcaactcca caactctttt ttctatatct ccaagcttat
    18901 ttatatatgc atcaatagca taccatattg aaatcaacag tttttcggca acttctgttt
    18961 ttactgatgt gctttgacca tttgtatatt ttttaatcaa gtccataagt attagagata
    19021 cttcttgttg tatattatat acttctcttt catctatcac tttacaattt agacattcct
    19081 taagtagaga tatggaatat tggttcttta ttaaattatt ttcgtttata ttaatattac
    19141 ttaaattatt taacatacaa aatctctcct atcatatatt aaacttctcc aaatttaaat
    19201 ttctttgcaa attcgtctgc ttctcctctt acattgtcca tattgcctga aaatttttca
    19261 taaaattcac ccagtatttc tataatctca tcatcacata tcttgtcatc agtttcattt
    19321 tttaaataat aaaaaatttc ttgcatatca ttaatagcct ctaaataatt gtccacattt
    19381 gtatattgtg atgtatatat attttctatt aactgttttg taacttttat atctaattct
    19441 attcttccat acccctttaa agtattatct ctcgaattta ttatatcttt tacatcagat
    19501 tcagaaagag ctagaccata atctccagat tctatattag tttcaagcag ttcatttctt
    19561 tctatttcct ttaaattctg atttatagaa ctcaaaataa taggtgatat catttttaaa
    19621 ttctcctttt ttattttttc cattgacttt ttttgttttt tatgctatac ttaaattaat
    19681 gtatattatt ttaccaacca cttataatag tagtgttaaa agtggttttt gtcaactcaa
    19741 aattactatc tcaattaaac ttttcaattt tctcaacaaa aaaataccat catttagata
    19801 tataattttc tataacaact tttaattcag tagttattta ctaaaatcta aacaatgata
    19861 tatttattaa ttttatttat cttttttggc tctacttcta cttttcttta catttgagca
    19921 atttctacaa gaaggtgaac agtattgaga tttagaattt gtaggaatat aaattttacc
    19981 acagtacttg catttattta aagaagaagg ttcacttgta attgcaaagg catagatagt
    20041 ctcaatagct gttttcaaag aatcaaactc ccatgcaata attggtttat ctaattggct
    20101 tatagaaaat cctatctttt gaggattaaa ccctccagac ataatagtaa cactttcagt
    20161 taatagatta gatgtatttt tatatacaca aatttgatta aaatgcttac acatatcttt
    20221 agcaaaactt acaatccaat ctagttgttc agtgtagaac tttgaaaata ctaaatctaa
    20281 aatcaatggt ctctttccaa aaaactttgg agattcttct ctctttgata catctatacc
    20341 ccttctatac tttttaaaat acacatcttc atcacttgca aatggtataa acatgtttac
    20401 atattcatct gtactcaata tattctcttt tgtaatataa ttcttttcaa tcatcagtac
    20461 tctttcttct ccaactatat ctctattata tacacttgaa tatattaaac ccaataatcc
    20521 atactttttt acaaattcaa gtacttcttt ctttagtttc atttcttttg tctcttttga
    20581 tatatcttgt aatgcctctt gtcctatgcg aattatatct actattatat catctgctac
    20641 atcaaatggg ttatacatgg taaacacagc atcttctgtt ggaactatat ataattcatc
    20701 ttcttcagta attttatatt cataatcact atacctaatc caatcacttg caaaattccc
    20761 tattaattct atttttttat tcataataat cattcacacc tttcaatgta atatataact
    20821 tcatattact attacacttt tagtttattc catattttct acactgtcaa ctattctttt
    20881 tatattttta gcatattaaa atttataata gcctttataa tggattttta cagctaaatt
    20941 tcttgtttat tgatgactaa ttcataatta aatttataaa aactatttac atataaaatt
    21001 aatctcttta taattgatat gtaatatatt tttacactta catattacat atcaattata
    21061 aagagaggta tctaaaatca tggatagaaa acgtgaatta aaacaattat acaaagaaat
    21121 gaaatttgac acaggtgtat tcataataaa aaatgatatt actaaaaaga tttaccttgg
    21181 aaaaagtaat gacataaaaa gcaaatttaa ctctctcaaa tttcagcttg gtgctggctc
    21241 atgtatgata aaagaattaa ataatgaatg gaaaaaatat ggtgaaaaag catttacatt
    21301 tgaagtttta gaacttataa aacatgatga taacaaaaca gagaaagact atttagaaga
    21361 actagatatt ttagagatgg tttggttaga aaaattaaag gaagataata cttatgaaat
    21421 ttattccata taaaaaataa tataatataa gaaaagtaga tagtgtctca aaatagacat
    21481 ttagttcata agatactttt ttatataaaa taaagtatct tttcataatt ttaacaatga
    21541 aaaagaggct tatctccatt tgatagcctc ttcccatata ttttatacca ttataaaatg
    21601 aacaatctac taattttcaa tgtatatatt cattttacta ataacactcc attacttctt
    21661 tacagcatcc aaacattgct ctataatact cttatcactt atacctattg ctgttacttt
    21721 actagctcca cttaatatac tcttatcact tttatttgaa actaaaacaa caggagcatt
    21781 ttttgcaagt ggtgatgcaa ctaaagcata aactaaatca tctccacttg ttatatagaa
    21841 ctcttttgct ccattataga acttttcaat aacattttta ttagtttgat atctatcaac
    21901 accaccaatt ctagttgctc tatatctgct cactatgtaa tcacttaatg tagactctcc
    21961 tccaatagca tatactggaa caggagaaac tccaaaccat gggtctaagt ctgtgtcttc
    22021 ttctgctgaa ggtatatctt ttgtcaatat tataggagct ccatctctat aagcaacaga
    22081 tgcaacactt actgcatcag cttcatcctt aaatccattt actaaaaaca tcttatcact
    22141 gtttttaatt ttttctattt cacctgcaat tttataactt gtatctactc tatctacacc
    22201 atcaattctt ataacttgca ttcttctcat aagtaacatt ttttctacat ctttacttat
    22261 agaattttct ccacctatta catatatctt agtaactcta ttcagtcttt gaagtgttgc
    22321 ttctggtata tcatccttat tagttaataa aatagctgca ttatttactc ctgcaagacc
    22381 acttgcagca atcccatcta ccattgtaga gtctgcattg ataagaactg ctgttgtaaa
    22441 atcttgctta tctgaaataa gcccagctgt ttcatattta tctactcctt gaatattttc
    22501 aatcttatct agtgcgttta ttgatgttgg aaaactaaca cttaacagta atgctgaaat
    22561 acctaacgcc aatacctttt tactaatcct cataaattac ctccctaaaa caaatatatt
    22621 tagtattagt ataatataaa atcatttaaa aatagtgtaa aaatagttac acttttttat
    22681 aatttaaata attttagact aaacacaatt catccattaa aataacttca tttattctat
    22741 atgctaagcc atcccacgtt ttttttgaca tatctacaga tgttttctta tttgagttat
    22801 tcaataaaga ttgtatctta gaatctattg cattatacaa attattttca aaatcatata
    22861 actcttcatc ttttggaata ccttctttct ccataaaagg tagagaaaca tattctatct
    22921 ttccagaatt attaatctca ctaccaatcc actctttaac accaagaata tcagtagtga
    22981 ttacatctgt gccacaagat aaagcttcta aaactacaac tggtaatccc tcataaaatg
    23041 atggtaacac aaatatttgt gacctgttga atagctcagc taaatctctc tgttctaact
    23101 ttcctaggaa attcatttta aatggagact tacttgccag tttaactatc tcattatatg
    23161 attcgatatc gcttccagta cctgcaaaat tgacttctat taaatcttta ctatatttta
    23221 atttagatat agcttttata aatggaatca gtccctttga tttacatatc ttacctgcaa
    23281 atactatttt tattttatca tcctttattt tataattttt attataaaat atatcatcat
    23341 tataaccact accaattaca actactttac tttcacttac tccaaaagtc tttataatat
    23401 catatttctg attttcatga agagcaaata ttaaatctaa tttccttata tttgctatta
    23461 tgtattcttt ctctaaatca atggtattta actgtcttaa acaagttcca tgacaaatag
    23521 acataacctt tatatctttt accatttccc taacaaatgc agttaagagg tacaaatgat
    23581 gacatattat aagttctggt ttaaaatcat tcatagcctt atctatattt actttaaatt
    23641 gatatttcaa tctatttatc atgtctatat ttaaatcttt atatcttgta ctttcatatg
    23701 gcatagaatc actcatacct acaacaggaa aatttaactc cccacaatta tactttactg
    23761 gataaaaact tacttcactt ggaaaacaat ttacatcatc atttacatct atacctgcaa
    23821 ttacagcttg cttatgaccg attttttcga acccttttat cataccagac aaatatatac
    23881 cactacctgt actatttggt ttttgtgtta ttatatgaag aattttcact tttcacttgc
    23941 ctcctttcta aaattaaata gttttataca gtctaatcat tatatatatc taaatataaa
    24001 caagatgaat catcttttac tttaaatctt ggcactttaa ccgctttata gtcattatct
    24061 tcaaaatccc ttactttatt atgtatatat cctataccaa atttttctgc tatacgtatc
    24121 aattcttctt cttttattag attatatcta tcacatgcac ttgtaaaacc atcactcgtt
    24181 agcatcaatt gaaaatcttt ttttatttca atgtatccat atatagaatt ttccacagct
    24241 tcctcatcaa aatccaatat ccaatagccc tcttttgtat ttttcttcaa tctattgctt
    24301 actattgtat ccataacact agttctaatc tcatcaaaag ccatctcttc caagttagaa
    24361 agtttactca tttcatcaaa tacagtatta tcaaatttac aaatactcct atcttttata
    24421 actttggaat ctccattttt aataaacaaa gcacaatctc ctaataaaaa atactctact
    24481 ttattttcat gaaattttac aacaactata gaactagatg gtaaatctaa tttttcaacc
    24541 ttaaacccat ttaatcttag ttcatactct ttttttactt ctattattcc agtattaata
    24601 atactcttta atgattcttc tttatttata tttttatata aatacctatt ccaccactga
    24661 acataccacc ttgcgtcact ttcagttgac actaaatttt ttccattaag tcctgtagca
    24721 ccatctaaaa cccatgcccc aaatggattt ataccgacta catcttcatt aaatttagct
    24781 gttccttgat tacataatag gctatagttt cttatattta aagccatatc aacctccaaa
    24841 ttgaatatct aaaaataaag ttctatttaa aattatacag caaataaaaa aatctacaac
    24901 aaaacttgtt gtagattttt acttaatcta tattatcttt atactttcag tattttaatg
    24961 atggaataat ctatttttag taaatgccat gactatgtta tacttattac aagttaatat
    25021 aacattatca tcacgaatag aaccacctgg ttgtgctata aaacttaccc cacttctttt
    25081 tgcacgttct atattatctc caaatgggaa aaatgcatct gaaccaagtg ctactcctgt
    25141 taaagtttta agccatgctc tttttccttc tccagttaga ggctctggtt tttcttcaaa
    25201 aaagttttgc catatgccat cagcaagcac atccatataa tcatcagaaa gatatacatc
    25261 aatagtgtta tctctatctg gacgacctat atccttttta aattttaagt ttaatacttt
    25321 aggatgttga cgaagatacc aagtatcagc tttgttacct gcaagtctag tacaatgaat
    25381 acgtgattgt tgacctgcac ctacccctat tacttgtcca tctttagcat aacaaacaga
    25441 atttgattgt gtatatttta atgtaataag agctataatt aaatcacgtt ttgcactatc
    25501 tgtaaaaatt ttattatcag ttggaatatc ttttaatagg tcttcattta ttaatatttc
    25561 atttctacct tgttcaaaag taattccata aacatccttt gtttcaatag gttcaggagt
    25621 ataattttca tctattttta caatattata gttaccttta cgctttcctt ttaatatttc
    25681 aagggcttca tctgtatatc ctggagctat tataccatca gaaacctctc ttgctataat
    25741 agttgcagtc tccttatcac atacatctga aagtgctata aaatcgccat aagaagacat
    25801 tctatctgct cctcttgcca ttgcataagc acaagctaat ggagaaagct ctaaatcatc
    25861 aacaaaatat atttgcttta aagtatctga taaaggtacc cctactgctg ctcctgctgg
    25921 acttacatgt ttaaatgaag ttgctgctgg aagacctgta gcttctttta attccttcac
    25981 aagttgccaa ctattaaatg catctaaaaa atttatgtat ccaggttttc catttaatac
    26041 ctctatagga agttctccat tcttcatata aatctttgat ggtttttgat ttggattaca
    26101 gccatacttt aattctagtt ctcttgccat atactcatcc ctctctataa taaattaatc
    26161 ataagtttga ttaatcctat attaattaaa ttattcgtac taataaaatt atatggcata
    26221 tttatccatt aatcaactat attttttaaa actcctattc cttcgacttt acattcaact
    26281 atatcgccat gctttaaata tacttgagga ttcatcccca tagcaacccc tgctggagtt
    26341 ccagttgaaa ttatatctcc tggctttaga gtcattcctc ttgataaatc atttattata
    26401 gtaggtatat caaatataaa gtactctgta ttagaatctt gtcttacttc tccatttact
    26461 acactactta tatctaattt taaaggatgt tcaaattctt ctttatgtac tatacaaggt
    26521 cccatagatg tatgtgtgtc taagcttttt cctctaaacc attgaacatg tttatcttga
    26581 agtgctcttt cacttatatc atttactatt gtatatccaa atatatattc ataagcatct
    26641 tcttttgata tatttatacc ttctttacct atgattactg caagttctga ttcatagtcc
    26701 aacttctcta ccaaatctcc atgtaagctt atcttatcat ccactccaat tattttgtct
    26761 gctctcttag aaaaataaat tggataatct ggcataacta cgttttttat aactccatct
    26821 gggatttcat tgacatggtc tttatagttt agacctaaac atataatatc ttttttaggt
    26881 cttacaattg gggaacataa tttaacttct tctaacttat aacactttgc gttttcaaat
    26941 gaattgtttt ttattttttc taaatctcct gtagatacgt tttcaataaa atcattcata
    27001 tcagtatata atttacttaa tcctaaacta ttaatttcat atatactatt tgtttctgaa
    27061 ttaaatacac ctattttttc ttcattgcta ctacaaaaag tcacaaattt catttttatt
    27121 cctccattca ataagttgat taatattatt taatttttat tagtttatat aaattgtaat
    27181 tcataatatt tatatgtcaa tacatattta tatattttaa aaa
//
LOCUS       DAEHWO010000051        25938 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEHWO010000051 DAEHWO010000000
VERSION     DAEHWO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25938
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.051"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(126..1133)
                     /locus_tag="KNP54_002547"
     CDS             complement(126..1133)
                     /locus_tag="KNP54_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBF0893424.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            1361..2245
                     /locus_tag="KNP54_002548"
     CDS             1361..2245
                     /locus_tag="KNP54_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0893425.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            2447..3997
                     /locus_tag="KNP54_002549"
     CDS             2447..3997
                     /locus_tag="KNP54_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBF0893426.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            4026..4673
                     /locus_tag="KNP54_002550"
     CDS             4026..4673
                     /locus_tag="KNP54_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBF0893427.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(4815..5075)
                     /locus_tag="KNP54_002551"
     CDS             complement(4815..5075)
                     /locus_tag="KNP54_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBF0893428.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFRYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            5292..6575
                     /gene="hflX"
                     /locus_tag="KNP54_002552"
     CDS             5292..6575
                     /gene="hflX"
                     /locus_tag="KNP54_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBF0893429.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYANLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDADLDEEDFNIYREYILEK"
     gene            6583..7260
                     /locus_tag="KNP54_002553"
     CDS             6583..7260
                     /locus_tag="KNP54_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBF0893430.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            7346..7789
                     /locus_tag="KNP54_002554"
     CDS             7346..7789
                     /locus_tag="KNP54_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBF0893431.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            8094..8738
                     /locus_tag="KNP54_002555"
     CDS             8094..8738
                     /locus_tag="KNP54_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBF0893432.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(8824..9201)
                     /locus_tag="KNP54_002556"
     CDS             complement(8824..9201)
                     /locus_tag="KNP54_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBF0893433.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(9201..9587)
                     /locus_tag="KNP54_002557"
     CDS             complement(9201..9587)
                     /locus_tag="KNP54_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBF0893434.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            9766..10521
                     /gene="nadE"
                     /locus_tag="KNP54_002558"
     CDS             9766..10521
                     /gene="nadE"
                     /locus_tag="KNP54_002558"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBF0893435.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            10604..11323
                     /locus_tag="KNP54_002559"
     CDS             10604..11323
                     /locus_tag="KNP54_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBF0893436.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(11490..12494)
                     /locus_tag="KNP54_002560"
     CDS             complement(11490..12494)
                     /locus_tag="KNP54_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBF0893437.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            12760..13656
                     /locus_tag="KNP54_002561"
     CDS             12760..13656
                     /locus_tag="KNP54_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBF0893438.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            13777..15039
                     /locus_tag="KNP54_002562"
     CDS             13777..15039
                     /locus_tag="KNP54_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893439.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            15115..16308
                     /locus_tag="KNP54_002563"
     CDS             15115..16308
                     /locus_tag="KNP54_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBF0893440.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            16937..17731
                     /locus_tag="KNP54_002564"
     CDS             16937..17731
                     /locus_tag="KNP54_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBF0893441.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDVAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            17826..19166
                     /locus_tag="KNP54_002565"
     CDS             17826..19166
                     /locus_tag="KNP54_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBF0893442.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            19303..20535
                     /locus_tag="KNP54_002566"
     CDS             19303..20535
                     /locus_tag="KNP54_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBF0893443.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     TLIESGIVTMNKEACEIC"
     gene            20575..21717
                     /locus_tag="KNP54_002567"
     CDS             20575..21717
                     /locus_tag="KNP54_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBF0893444.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            21728..22522
                     /locus_tag="KNP54_002568"
     CDS             21728..22522
                     /locus_tag="KNP54_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBF0893445.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            22533..23555
                     /locus_tag="KNP54_002569"
     CDS             22533..23555
                     /locus_tag="KNP54_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBF0893446.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            23654..25030
                     /locus_tag="KNP54_002570"
     CDS             23654..25030
                     /locus_tag="KNP54_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBF0893447.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(25362..25706)
                     /locus_tag="KNP54_002571"
     CDS             complement(25362..25706)
                     /locus_tag="KNP54_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893448.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
BASE COUNT         9792 a         3044 c         4845 g         8257 t
ORIGIN      
        1 aatttatatt ttatactatg taaaatatct aatatatttg gtctgtaggt taaataaaag
       61 tacctttaga ccaaatatat tattaataac ttaataacat cttaaaactt atttatttat
      121 attatttaca acatccattt aataaataca ccataaccta cagctgggtc gttttcaatt
      181 gcatgtgaca ctgctccgat tattttatta tcttgaacta ttggagtacc actcatacct
      241 tgtacaatac caccagtttg agctaaaagc tttttatctg taattttaat tttaaaactt
      301 ttactttctg gatgtttttg gttttctata tctataattt caatattata ttttttacac
      361 ttattaaagt tatcttgtaa aattatttga gcttttccta atttaacttc atctaaagat
      421 gctactttat atttttttaa cttggaaata tcaaagttat taatttgacc tcttattcca
      481 aaatcagtat tttctgtaaa gctaccaata atattttctc gttttgcatt tatacatcca
      541 acactacctt tataagattt ttctatatta aggtgcttag ttgtagaaat tgaacctgtt
      601 ttaataggta tttttcttgc attaccaaca cttattggat gacctacagc tccaaactct
      661 gatgtatctg gattgatata cgttaaagta gcaaatccag aaagtaaatt gttaaaacta
      721 attttttcta atatgtgttt ggtagttttc attgttataa gttgtccacc tctatttaat
      781 aaaatagata cttgtttttc ttctggtaaa gcatttaagg tattggcaaa gtcactatat
      841 ccatcaactt cagcattatt tacctttact atagcatcac ccaatctaaa tggagatgct
      901 tctccaggat ttctaactat gatatttttt aattctgcgt caatttgaag tacgtttcca
      961 attggtatta aatattcagg ttcatttttt tgtaaatttt gtgcataaat taaattattt
     1021 gagaaaaaat ataataaaaa taaaaatgtt aaaacaattg taaattttga cttagctaag
     1081 ttggtttttt tacttaaagt attattttta aaatgaaaat ttttaagttg cataaaacac
     1141 ctctttctta ttaaattatt ttaataatag aattgaagtt ttcttgctgc ttctatatta
     1201 tgttgtgcaa gaatcatgtt ttgatgcttg gaaaactagc tcaataacac cttagttttc
     1261 ataaaaataa ataaaataaa tagtgtatat gataaaataa atacatattc atataaataa
     1321 aaataaacaa taactgtcta gcataagaaa ggagcaaaaa atgaaaaaat atagattgtt
     1381 agttacttgt ataattgcca tgggaatcat aattatagga acatcaaatc cagttagcaa
     1441 tttttacaag actacaaatt tgattagttc aggaaatatc acaaatgaaa aagcagataa
     1501 agatgaaaat tcaaacaaaa ataataaaga taaaaatgaa gacaaatcta attctaaaag
     1561 taataaagat aagtcatcag aggacaaatc gtcagataat aaaaatgaaa ttcaaaaaaa
     1621 taaaaaactt ttaatttgta tagacccagg gcatcaagga aaaggagata gcaatttaga
     1681 accagtagct ccaggttctt cctctaaaaa agcgagagta tcttcaggaa cagagggtat
     1741 tgctacaaaa aagccagaat atgttttaaa cttagaagca tctcttgttt taaagagtat
     1801 attagaatct aaaggttata atgtaataat gactagagag acacatgatg taaatataag
     1861 taattcagaa agagcaatac ttgctaatga caaaaaagca gatatggttg taagaataca
     1921 tgcagatagt ttaaataatt cttcaaaaac tggagcatct atattgattc ctgaaaaaga
     1981 tggaaaatat acagctccta tatatgaaga aagtaataaa tgtgctgaat ttatcaaaca
     2041 gaatatggaa caatcaggta tacaaatcaa tggaatcgtt caaagaggtg atttgactgg
     2101 attcaactgg tcaaaagtac cagctgtatt agtagaaatg ggatttatga gtaactataa
     2161 tgaagaccaa atgatgtcaa atccagacta ccaaagaaaa atgatgcagt gtatagctga
     2221 tggattggat gcgtatttta aataagatat gaatagagaa aaagttaggt tggtattatt
     2281 tgcctaattt ttatctctat tttttattgt acataacaca aagaagaagt ttattttagg
     2341 ttaaattgtc gtaaatataa ctaaaaatat tgggaatact tgatttaagt ttaaaaagaa
     2401 tatattatag tatagaatgt gtaaaatttt tttgagaggt gttgaaatgc tagtagtaga
     2461 aaatgtgagt catggatttg gtgcgagaac aatattagaa aatgtatcct ttagacttag
     2521 aaaaggtgaa catattgcac tagttggtgc taatggagaa ggaaaatcga gttttttaaa
     2581 tataataaca aagaagctta tgccagatgc tggaaatata aaatggtctt caagagctac
     2641 agtaggttac ttagaccaac atacggtatt aagcaaggga aaaactataa gagaagtgct
     2701 tagagaggct tttaagcata tgtttgactt agagcaagaa atgattgcta tgtatgacaa
     2761 aatgggagaa gctagtgatg atgaaatgag taagcttctt gaagaaacag cagagataca
     2821 aactatactt gaaaatagtg gtttttatat gatagatgca aagatacaag aagttgcaaa
     2881 tggtcttggt cttggagaaa ttggtcttga taaagatgta actgacttaa gtggagggca
     2941 aagaacaaaa gtacttctta ctaaacttct acttgaaaat ccaactattc ttatattgga
     3001 tgagcctaca aactatttag acgaagagca tataacatgg cttactaagt accttcaaga
     3061 gtatgagaat agttttgtct tagtttctca tgatattgaa tttataaata atacatgtaa
     3121 tgtaatatat catatggaaa atggagagtt aaatagatat aaaggaaatt atgatgaatt
     3181 tgtaagactt aatgatataa agaaacgtca agaagaacaa gcttatgata aacaagttga
     3241 agaaagaaaa agactagagg attttgtagc tagaaataaa gctagagtag caactagagg
     3301 aatggctaac agtaggcaaa agcaacttga taagatggaa atattagaaa gaccaaaaga
     3361 aaaaataaaa cctacttttg cttttaaaga tgctagagca gctagtaaaa taatttttga
     3421 aacagaaaat ttagttttag ggtatgatga agcattgaca aaaccactta atttccattt
     3481 agaaagagga aaaaagattg ccttaaaagg aatgaatggt attggaaaat ctaccctatt
     3541 aaaaacttta cttggaataa taaaaccatt tgaaggaaat gttaaattag gtgactattt
     3601 ggaagttgga tattttgaac aagagagttc aagagaaaat agtaatacac ctatggatga
     3661 agtttggagt gaatttccag ggcttacaaa ctttgaagtt agacaggctc ttgcaaaatg
     3721 tggacttaca aatgaacata taacgagtca aatgagagta ttaagtggtg gagaagctgc
     3781 taaggttaga ctttgcaaag taatgttaaa aaatataaat ttcttagtat tagatgagcc
     3841 tacaaatcat ttagatgttg aggcaaaaga tgaattgaag aaggctatca aagagtttaa
     3901 gggaacagtt cttttagtat gtcatgagcc agaattttat tcagaaattg ttgatgatgt
     3961 atggaatata gaagatttta caactaaaat cgtgtagtga tttaacttat tgctgggggg
     4021 atttcatgaa aaagtttcta aatgtacttt tttcaatttg tattagtatt gttataatag
     4081 taggtgttat taattttact gttggattta aacaacttta ttattttgac attgattact
     4141 taaatatatc agagttatct ggtttatcta aagatgatat aaaattgaac tacgattatc
     4201 taattgatta taacttaaat aagaatgtgt ctgagttcaa attaccaaca ttaaaatctt
     4261 ctccacaagg gaagatacat tttgaagaag tcaggaatat atttcaaaat ataaataaat
     4321 tagctaaatt attattggta gtttctttag taggaattat attgagtgta aaaaataaaa
     4381 atataaaaat cttaaaaact acatcaataa cacttataat tatgccatta ttattaacag
     4441 ttccaatttt attaaatttt gaaaagtcat ttattatttt tcataaatta ttatttagaa
     4501 atgattattg gatatttaat cccgatttag acccagttat aaatatattg ccagaggaat
     4561 ttttttttca ctctggaatg atgattttaa tattaatttt gttagtaagt atagtactgt
     4621 ttgtaatgta taaattatgt aaatctttat caataaaaat atttcaatgt taaatagagg
     4681 gatattttta tttccaaaat aagataataa aaaaggatta gattaaaagt tatacaataa
     4741 aaatagctgt gcaataatat ttagactatg aaagtagttg aaaaatattt atgcacagct
     4801 atttataata gaatttactt tttactagtg attttaacta aatcttgaaa tttactcata
     4861 atgtaattgt aattatcttt tttatgaggt aatatacaac tactgcaatc tttgatacct
     4921 ttatctgtat acctaaagtt tccaccacag ttttctccta aagcatacaa aggacaatag
     4981 caaaatagac agttaaactc ttctggttta ttagttttat gacaagggaa aaattcgcaa
     5041 tctttgtgat taaaaaactt ataattttcg cccatatttt cctcctaatt aaataaaatt
     5101 taaatttttt atactatata agattttggt gataatataa ttatactaaa taattttatg
     5161 aatagtcgat aatatagtat tattaatcat agtattaatg gtataattag tcaacagaaa
     5221 aataatgtaa aaataatgta agtgtatttt gtaattagaa tatgttttat aacaaaaaat
     5281 gaggtgatta agtgaaagaa attcaagaaa aagcacttct tgtaggtctg aatttgacta
     5341 caatagtgaa aaaaaatgat gatatagaca ctaatgaatc tatggaagaa ttaaaagaac
     5401 taacaaaagc tgctggggca gaagttgtag gtagcttaat tcaaaataaa cactctgtag
     5461 atgcagctta ttatatagga aaaggtaaag tagaagaaat aagagcctat agtgactctt
     5521 tagatgctac tttagtaatt tttaatgatg aattatctgg tgctcaaatc agaaatatag
     5581 agaatgttgt tggaagaaaa gtaatagata gaactacttt aattttagat atatttgctc
     5641 aaagggcact tagcaaagaa ggtaaattac aagttgaatt agcacaatta aaatatagat
     5701 tgccacgact ttatggaatg ggtggtgaga tgagtagaac aggtgcaggg attggtacta
     5761 gaggtcctgg agaacaaaaa ctagaaatag ataagagaca tatacttaat aaagcagcag
     5821 atataagacg tgaacttaaa gaagtaaaaa agaatagaga gacacagaga gttaagcgtt
     5881 taaagtcaaa tataccgatt gtagcacttg ttgggtatac aaatgcagga aaatctaccc
     5941 tgttgaacga attaataaag acacacaagg attatgaaca agaaaaagaa gtttttgtaa
     6001 aagatatgct ttttgcaact ttagatgtaa ctttgagaaa ggctcttttg ccgaataaaa
     6061 aagaattttt agtagtagat actgttggat ttgtaagtaa acttccccat gatttagtag
     6121 aagcgtttaa ggcaacattg gaagaagtac agtatgcaaa tttaatctta catgtaattg
     6181 atgcaacaaa tactagttat gaattgcaaa aaagtacgac tgaaggtgta ttaaaagaac
     6241 ttggtgtaaa tgataaaaaa catatacttg tatataataa agtggacaag ctagaattgg
     6301 atatataccc taaaagtcaa gaagatattg tgtatatttc tgcaaaacaa ggcataaata
     6361 tggataagtt attaaatatg atagaaattg ctttaatgga aaatacttat tcagtaagtt
     6421 tgatgttacc ttatgagaga ggtgatatat ttagtagaat aaaagataaa tataatgtgg
     6481 agaattttga gtatggggaa agtggtataa cgctagatgc agatttagat gaagaagatt
     6541 ttaatatcta tagagagtac atactagaaa aataggttga atatggatat aaactgggaa
     6601 aatatagata atcttgaaga ttattttata acctatcttc tttataaaga atctaaaaca
     6661 gtatctcaaa ttagtaaaat tagaaatatt tcaagtactg aagcaagtga gcaacttata
     6721 caagcaaagt taaaaataaa ggaaatgcaa aaagatgatt ttgaggcatc taaggatatt
     6781 ttggataaat ttctagaact agataaaatt aagagacttg attttatgga tagcttagat
     6841 gacgaaaaaa tggtatactt taagagaaag gttttcaaaa gaatccttgt agaaaaaaat
     6901 gctgaagatt taattgtttt aatttgggcg acaggtgagc taaaagatga taggtttttg
     6961 aaattgcttc atcagctcac aaaccacaga cactcagata ttagaagaat aacttattca
     7021 gcaatcagaa agattgaatc accaagtagt agagaagtac tgcaaaaagg tctctacgac
     7081 aaaaatgcac agactaggca gtactgtgca aaagctcttt caaaattggg agatgaaaac
     7141 agtttaaaga ttttacagca gttgaaagac aagaataaga attttgaaaa agaatatgtg
     7201 cttagagctt atgacgaagc cattaagtca ttggaaaatg caaaaaattt gaaaaagtaa
     7261 ttttttatta aagcaatttg tttacttaat gatgtatttc taaagtttaa caaggtaata
     7321 aataaattaa tgggaggggt ttcaaatgat agtaagacgt tgtgcaggtg gagtagtgtt
     7381 ttatgctaat aaagtactta ttgtaaaaaa tgataggggt gaatggacac ttccaaaagg
     7441 aaagatacta ggagggggac ttccatatga gagtgctgtt caaagagtta aagtagaaac
     7501 tggcatagat gctaaaatga tagatgtggc tggcgatact atgtatgaat ttttctcaag
     7561 aagtagacaa caagaagttt gtaatgcaat aatgtggtat gttatggaag cttgtaacac
     7621 tgattgtgta cttgctcctg aatttcaaga aggtggattt tataaagtaa aggatgcttt
     7681 agaaatgtta tcacatcata aagagcaagc tttagtagaa gtatcttata aaaagtttaa
     7741 ggaattaaag aaattagttt cagagggcga tgatgttcca gcaaattaat tgtgaattta
     7801 gaggattctg aggaagggat agccccttcc ttttttaatt gaagcagttt taagcgtaaa
     7861 ttatatagtc tctttaaact atgatttatc aatttagaga tttagtagtt tatatttaaa
     7921 atcagtaaga tatatttaaa ataaaaatta aaaagtatac aattttatta tataattgtc
     7981 ttatgatgtt gattaaagaa gtattaaaag tccatttatt tttaaataga atgattttat
     8041 aaatatatat ttgatgtgta tattagaaaa tgattaaaat aggaggaaat acaatgagca
     8101 attacaggac attacatgaa tttggaacgg atgaaataac gattgaaaag tctgttttta
     8161 ttggatatgc taagcctata aagagtgaag aagaagcatt agagtttata aatgaaataa
     8221 agaaaaagca taaagatgca actcataatg tgtgggctta tactgtaggt aaaaatatga
     8281 atatacaaag atatagtgat gatggagaac cacaaggaac agctgggata cctacattag
     8341 aggttataaa aaaagaagat ttgagagatg tagcggttgt tgttactagg tattttggag
     8401 gaacaaaatt aggtgcaggt ggtctagtta gagcttatac aaaaggtgct aaactgggac
     8461 ttgaagcagg taagataatt tataaggtaa tgtatcaaga agttaaggtt aagatagatt
     8521 atactcaact tggaaaagtg caaaatgagt taatgaattt ggggtatttt ataaaagata
     8581 ctgtatatga ggataatgtt gaaatagtag tatattcaag attagaagat gtagagaaat
     8641 tatcagaaaa aatgattgat ataacaagtg gaacaggaaa aatagtttta ggagaggaat
     8701 tttatttgtc tgaacaaaat ggagaaattt taatataatc taaaaggtta ttagaatagt
     8761 taatacctca aatagccaat tagtattttt aagtgaaaag ccattaaatt gatttaatct
     8821 aaatcaattt aatggctttt tatcggattt tgcacagaat ccttttttta cttcaaataa
     8881 accgactaaa agtaaaaata tcccaaatat tttttttaat atatctgaag acagataatt
     8941 agctaatagt gaaccaaata cagctcctaa aaccccaaac acagctatag gtataaccaa
     9001 tttaaaaatt acatttttat tttttatatg tatagcaagt gctataagtg tcatagggat
     9061 agatgaaagt aaatttacgc tttgtgctat tttagtgtct atgccagcaa gtaaaacgag
     9121 tgcaggtata aggattgttc ctccacccat tcccattcct ccaataattc ctgcaaaaaa
     9181 tccaattaga gcaaataaca ttaaaacacc atccttaatg ctgcaattat cataattatt
     9241 ccaaaagaaa ttctaagaaa ctttccagta accttattta gtaatttagc tcctataata
     9301 ccaccaagaa tacttccaac tgcaacttta attgttaagt taacatcata agtaccttta
     9361 gatacatata aaacagaact tgctgtcgtt aagaatatta ttatagaaag agcagttgca
     9421 tgagatttat gttcttctac cttaacgatg tcatttaata ttggaactaa aagagtacct
     9481 cctccagaac caaaaactcc atttataaat cctgtaaaaa ctccaattat cgtatttttt
     9541 aaattaaaat caaagtattt tttctttaaa tcatcagttt ttttcataaa aatcaccttc
     9601 tgaaatagtt ttaccaaaat aggcaaatta tatttatata aaataagatt aaatataatc
     9661 tttcatgttt gtttaatttt gcataaaaaa aaacatatta aaacaacata ttaatatatg
     9721 gtataatata ttaaaacaaa gtagcaaatt tgagaggaga taacaatgtc aaatataaaa
     9781 atacaaatag acaaaactgt agaatggctt ataaataagg ttaatgaggc aaatgcaaaa
     9841 ggattaattg ttggtgtatc tggaggaatt gattcggcag tagttgctaa tttaattaaa
     9901 aaggcatttc cagaaaactc tatgggagtt ataatgagca taaaaagtaa tcctcaagat
     9961 agagaagatg cacttaaggt tatagaggga tgtgatatag aataccttga tttagacctt
    10021 atagaaccac aaagtgctat attagacatg gtagtaggaa atttaaaaga taaacattta
    10081 tatagagaag aatatttaaa gatgacagat gcaaacttaa gagcaagagt aagaatgagt
    10141 acaatttata caattgctaa caatctagga tatctggttg ttggtacaga caatgctgca
    10201 gaaatacaca caggatattt tactaaattt ggtgatggtg gagttgatat tttacctatt
    10261 gcaaatttaa ctaaaggaga ggtgtatgaa tgggcaaaag agcttggtgt tcatgaagat
    10321 ttaataaaca aagctccttc agcaggtctt tgggaaggtc aaacagatga agatgaaatg
    10381 ggaactactt acaatatgat agatgctgta ttagaaggta gattggatga agttcctaaa
    10441 agagaccaag agataattga aagacttcat agattaagtg aacacaagag aaaaacgcct
    10501 gcacaacctc ctaagttcta atttactatt tataagattt gtgataaaat ttacaagtga
    10561 tgaaaattag aataattaat tgtacgtatt aaggagtgga aatatgggac gtataggtaa
    10621 tataattaat agaaaaggta aacaagatgc tcaaagagca aagatattta ctaaacatgc
    10681 tagagcaata gcagttgcag ctaaggaagg tggagcagac ccagagtaca atgcagcgtt
    10741 aaaaacagct atagaaaaag ctaaggcaga taatatgcca aatgataata tagatagagc
    10801 tatcgctaaa ggtgctggag caggtgctgg agaagactat gaaactatag tttatgaagg
    10861 atatggacct ggtggagttg ctgttatagt agaaacttta actgacaaca aaaacagaac
    10921 tgctggtaac gtaagatact attttgacaa aaacggagga aacttaggaa ctagtggatg
    10981 tgtgtctttc atgtttgata aaaaaggaca aatattagtt ggtttaggag atggagtttc
    11041 agaagaagaa ttgatggatg ttgcattaga agcaggagct gaagatttca taacagaaga
    11101 agatggttat gaaataataa ctacaccaga agatttttct agtgttcgtg atgagttaaa
    11161 agctaaagga tatgagttta tatctgctga tgtgaagatg atacctcaaa ctacaactgt
    11221 attgactgaa gaatctcatt taaaaatgat gaataaatta gttgatatgc ttgaagaaga
    11281 tgatgatgtt caagatatat atcataactg ggaagtagaa taaatagtat aagcatattg
    11341 aaatttataa gtattgaatc aattttaaca tgtgataaat tttatagaat aagaaacact
    11401 aaaatagaca tacgcacctc taacctatat ttgcataata atatgtaagc ataggtaagg
    11461 ggtgttttta tatttatagg ttaagaaatt taaagtaaat tttgagctgg actcgattgt
    11521 ctataaataa ttgatgggta tataacttgt tgctgaatac catttatacg cccagttact
    11581 gtatcaataa tcatcctaag actacgttct gctgtctctt ccatttttaa atctataact
    11641 gtcaaaggag gaatacttct tgccattagt cgtgaaggtc cattacttgc tgcaaatatt
    11701 tgaatatcct ctccaattac aattcccgat tcatgaaatg cattcatcat accaagagct
    11761 accacatcat gattacaaaa aattactttt tttagtgaat tttttgcaag cattttttga
    11821 gcaatatcat atccactatc tattttatta gaacaataat atatagaatc tgatagatgt
    11881 attccatgtt ctttacatgt ttttaaaaaa gatttacccc ttaaagtcat acatgtaaag
    11941 gaagttgggt tgaatacaac agcaatatca tttttaccat tttgaatagc atgtaaagct
    12001 gctatacgac cagtttcctc attatcaata gatacacttg aaaaaccagg tatttcacga
    12061 tttacaacaa ctacaggaat tttaggttta ttttttacta gatattctat atcatcagca
    12121 ttgatacctg ttaaaacaat tccatcataa taattatttg caaaaaagta ttcatcatca
    12181 catagatgac caactttgta aggtcgtatg atgatattta tgtttaaatg ttctaaagaa
    12241 attatgtggt ttattgcttg aagtatattg gttgatgcca actcaaatcc ctcatcctgc
    12301 caataaaaag ctattttaat attattatgt ttaataggag tagagcgttt atatccaagc
    12361 ttatcagctg aatttaatat aagctcttgt gtatgtagcg gaatcctgcg ttcatttcct
    12421 ttaccactta agacgtacga gacagttgct gaagaaagac cacagtcttt tgcaatatct
    12481 ttgattgttg ccatgataaa atcctcctta aatagttgct taaatttgct tataccaata
    12541 atcttaacat atattcaact aaagaacaat attctacaag gtgcatattt tacaggatta
    12601 gaataaataa attaaaaaaa acttcttact tatgttgaca taatttagtt tataggatta
    12661 taatatgctt aaataagctt atgattaact tgaattaagc aaagttaagc aggaacatgc
    12721 aatgctagct tgcaatgtga ctgcaaaggg ggaaaaggta tgagtaaggt aaatatattt
    12781 gaagttggtc ctagagatgg atttcaaaac ctgaaagagt ttttagaaac tgataaaaag
    12841 cttaagatta ttgatggtct tattgcttct gggattaaac aacttgaaat tagttcattt
    12901 gtaagcccaa aagcaatacc tcagatgaaa gatgcaaaag aagtagcaac ttattgtgta
    12961 gaaaaatatc ctgatgtgaa actttatgca ttagttccaa atttatatgg tgctaaagtt
    13021 gcatgggagt gtggtataag agatatatcc tatgttatat ctttgagtga aactcataat
    13081 aaaaaaaata taaatcgtac ccatgaagag tctattgatg agcttaaaaa aataatgaat
    13141 acttatccag acatgaatat atgtattgga atggctactg tatttggatg tccttttgaa
    13201 ggtttaccaa aaattgaaga tgccataaga tttgctaaac gcctttggga aaacggtatc
    13261 agggagataa atctagcaga tacaataggg attgctgacc ctaagcaagt aagagaaact
    13321 attagtgcat tagttgaagc tttaccagaa tgcagatggc aagtacatat tcatgatact
    13381 agaaatatgg gaatggttaa tactcttgtg gctattgaat ctggaattac tactgttcag
    13441 tctacacttg gaggattagg aggatgccca tttgctcctg gagcatctgg caatactgca
    13501 actgaagatt tagtatatat gcttgaacgt atggggtatg atacaggagt tgattttgtt
    13561 aaacttcttg aattatcaaa atatcagaag agttttgtaa atggagtata tagtggtcat
    13621 catgtaaata taaagtctga tagttgtaat tgttagttct attgattaat cgattaaaaa
    13681 aatatgctga ttggtaaaat agatttattg ataaaaaata taaattataa aatacattat
    13741 ctaataaaac aaataaaaaa attgaggggg attagtatgg atattatagc tttactttta
    13801 tttttaggag ttattattat tgcatttgta cgtaagaata atgcaggtat tttggctcta
    13861 gctattggtg tcatagctgt tagaattttt ggaatggatg ataaagaact ttatggagct
    13921 ataagcaact caatgtttac tacacttgtt ggtataacac tactctttgc aatagtgaac
    13981 tcaacaggag cattaaagct tgttgcagaa aaaattgtag ctgcttctgg taaacgtgtt
    14041 tggcttatac ctatagcagt ttttatagca ggatttgttg ttgctggtgt tggacctggg
    14101 gcaattccag cacttgcaat tatcccagca atggctgttc ctgtagccat aacagttggt
    14161 tataatcctg taatgcttgc acttataggt gaatgtggat taatggcagg tcgtatgact
    14221 cctattactc cagaaggtca aattataaca accgttgcag aaggggttgg aattgaaaat
    14281 gttatgccta ctatcttagc ctgtcaaact ctttctacaa ttgtattttc aatagtattg
    14341 tttataattt tcaaaggata taaacttaaa aaacctataa atgttataga tagtaagcaa
    14401 atagaaaaat tcaatataaa gcagataatt tctctaataa gcatagtagt tatgattgct
    14461 tttatcataa tttttgatat gaatgttggg cttgcagctt ttgcagtttc agctgtactt
    14521 atttttttca atattgctga tgaaggagaa tgtatcaaat caattccatg gagcacgata
    14581 gtaatggttc ttggagtagg tgcaatgatg acaatcgtag atgcagcagg aggtattgac
    14641 ttgatgagta atgcattatc atcactgatg aatagtaaaa cagctactcc aattatgagt
    14701 atttcagcag gacttatgtc tatggttagt tctgctttag cagtagttta tccaactatg
    14761 atgcctatgt gtgttgacat agctaaggca gttggaggag tagacccact agcacttatt
    14821 gctgcagttg gtgttggagg ttctcttgct ggtgtaagcc cactttctac tggtggggca
    14881 ttgattttag cagctatggg ttcaagtaag aaagacttta ataaggaaga acaaaataag
    14941 gtttttgtac agcttttcat tatgagtgca gttggcttat tggttattgc agtagtatca
    15001 atattatcat ttaatgcaat aacacattta atgaactaat tagaataact gaaaataaat
    15061 cattaaattt aacttttaat attaatcaat ataatataat ttggagggga agttatgaaa
    15121 aaaggagcat taagcaatat aaaggtactt gaccttacaa gagttcttgc aggtccatat
    15181 tgtacaatga tgttggcgga ttttggagct gatgttataa aaatagagat gccaagaaaa
    15241 ggtgatgata caagaggttt tggacctttt gtaaatggag agagtttata ctatgcaaat
    15301 ataaatagaa ataaaaaagg tatcactcta aaccttaaat cagaagaagg aaaaaatata
    15361 tttttagaaa tggtaaaaca tgctgatgtt gtagtagaaa attacagacc aggtgtaatg
    15421 gaaaagttag gtctgggtta tgatgagttg gctaaagtta acaatcaaat aatttatgga
    15481 gctgtatcag gatttggatg ttatggacca tattcagaac gtccaggtta tgatattatt
    15541 gcacaggcaa tgggtggtct tatgagtata acagggcaag aaggaggaga accaacgaga
    15601 gttggtaatg ctatgggtga tgtactaggt ggaatgaatt taactattgg tatactcaca
    15661 gcactcaacg ctagaaaaat aataggaaaa ggacaaagag tagatgtttc cctcgttgat
    15721 tctgttgtat cgtctctcga aactggtata cagagatact ttgattcagg acaacctgaa
    15781 cttatgggta atagatatgc ttcagcctat ccttatgact cttttaaggc aagtgatgga
    15841 agttttgtaa taggctgtgg taatgacaaa ctttttgaaa agttatgtaa aaaagttctt
    15901 tttagagaag accttttaat agatgagaga tttaaaacaa atcttaatcg ttgtgaacat
    15961 tacaaggctc ttaaaccaga aatagaaaaa tggtctgtta agcatacaat aaaagaagca
    16021 gttgacttaa tatcagaggc tggagttcct gctgctccta tctataatct tgattgtgtt
    16081 acaacagatg aacatatagc aaaagcaaga gaaatgattg tagatattag tcatcctatt
    16141 ataggaaata tgaaagtcaa tggaaatcca gttaagttga tgacaacaaa agctaaaatt
    16201 gatatgccag caccatctct aggggaaagt aacgaggaga tttataatgg ttggcttggt
    16261 tttgatagtg ataaaataaa agatttaaaa gaaaatggag ttatttgatt aaaaaatagc
    16321 taaacacact tgtgacttta gtcatgggag gttcagttag aataatatca aaaaatatta
    16381 aatcaatact gtaaataaaa tatagaattg tcagaagcat ttaagatggg aaaagctact
    16441 tagacattga gtctttgtgg cttttcctat tttcattaag aattttatat tatcagaata
    16501 gatatgtact aaactaaagt attaacaatt taaattaata gaaaataaac tacctaatta
    16561 tgttgaataa agactacttt agtgaaaata aacttataga gatgctattt aaattatttt
    16621 aatggaaata tcaaaaatga gactgcattc tcaaaaatga gactgcgttt tttaagtatt
    16681 ttctcgaaaa tgagacaaaa atattgtttt atgggtttta ttgaagaaaa attcttctgt
    16741 gaattacaat ttaatcaatt ttaaagttga aaattattaa aaatttagtg aaatttatgt
    16801 atatttcgtt tattttatta aaaataacaa ttttttacta aaaataaaga acttcaatgg
    16861 tgattggcat agtacttgct attttatatt aacaagaaat gtagaaaaaa taacaatgta
    16921 taatgggggg aatatgatgg aatctgtaat ggaaaatttg aacaatctta aggtggaggt
    16981 taaggacaaa gtctgtgtta ttactataaa tagacctaaa gctttaaatg ctcttaatag
    17041 tgacactctt agggaactat cacaagttat tgatgtagta tcagaaaatg aggcaatatt
    17101 aggagttatt attactggag aaggtaaagt ttttgtagcc ggtgctgata tacgccagat
    17161 gcaaaactat aaaagtgagg aaggcagaaa atatgcaggt tatgctcagg gaatttttga
    17221 taaaattgaa gctcttgaga aaacagtaat agcagcagtt aatggatatg cattaggtgg
    17281 tggatgtgaa cttgctatga gttgtgatat tagaattgca tcagaaaagg ctatatttgg
    17341 acaacctgaa gttaatttag gagttattcc atgttttggt ggaactcaaa gattatcaag
    17401 acttgttgga actggaatag ctaaagagtt aatttttacg gggagacaag taaatgcaga
    17461 agaagctaaa tctattggac ttattaataa agtggttcca agtgatttac ttttagaaga
    17521 gtctatgaag atgatgaacc aaatagttga aaaagcgcca atagcaataa gatatgcaaa
    17581 agttgttatt aacaaaggga tagatatgga tttaaagaat gctcttgaac tagagaaaga
    17641 tgttgcaggt ttaacttttg ctacaagaga taagcaagaa ggaatgaatg catttataga
    17701 aaagagaaag ccagtttttg aaaataaata gctattataa ctaaaattgg aacaatgtag
    17761 aatatattca aaatctaaat ttcgtgaaaa aatacatata gtttaatttt aaaaggagtt
    17821 aatttatgaa tacgggagta attataagtt tagtagggat tatcatagct ctatctcttc
    17881 tagttgtaat ggttatgaag ggaataaata tttttattat agcaattgta tgttcatcat
    17941 tagttgctat aacaggaagc ctaaatgtgt atgatgcact taaagtggat tatatgacag
    18001 ggtttgttgg atttcttcag gcaaatttct ttattttcct aacagggaca ttaatgggaa
    18061 aaataatgga gattactggt ggagcaaaat ctattgctaa gatgattgta agatggattg
    18121 ggaaggataa agcactactt tctattccaa tagcttgtgg aatattagcc tatggtggag
    18181 taagtgtttt cgttgtaagt tttgcagtgt ttccgatagc tttagaaatt tttaaagaag
    18241 ctgatttgcc acgaagattt ataccagcag ctttgacttt tggatgctca acttttgcta
    18301 tggttgcacc aggggcacca caaattcaga atattgttcc agcatcaaca ttagggacag
    18361 atattatggc tggagcagta aatggtttta tatcatgtgc agtaatgttt atagttggaa
    18421 gtacaatttt gtacaaaatg gtttcaaaag aaaaagccaa tggtggtcat tttatagcac
    18481 atgaatcaga tatatttgat gaagcagaag caactaattc taagagagaa aatggtccca
    18541 atggtgtaat tgccttaatt ccattgatag tgtcgatttt aataattaat gtaaaagtta
    18601 atggaaaagc gatagtacca attgaggtgg gagtatttat tggagcttta ttagtatatt
    18661 tattgttaaa taaatatcaa gataatacta aaatagttgg acatgttggt gatgcatgta
    18721 aaactacagt agtagcaata tgtaatactt gtgctgtagt tgcatttggt tcagtagtaa
    18781 aatcagcagt tggttttgac ttcatagtta atgctatgac taatattcct ggtcctccta
    18841 ttgcaggggc tgcagttgga actacagtta ttgcaggtat ttgtgggtca gcttcaggtg
    18901 gactaggaat tgcagctcca cttcttggac cagtattttt agccaagggt gtttccgctg
    18961 cagcattaac taggactatg gcaatttcat cagcagcatt agattcactt ccacacaatg
    19021 gatatattgt tactgtaaca aatggtcttt gtaaagaaac acataaggat gcctatatgc
    19081 caatattctg ggtaactgtt ttaaccccat ttattggaac catagtagca gtcctactgt
    19141 ttacaatgtt cccgggattg ccataggaga aaagataaaa ggtataaatt atattttgat
    19201 attataaaat caattttcaa aatatataca ataaatttca tgttttaata ctgtaaatat
    19261 gtatttaaaa taacaaattg accatataag gaggaattga aagtgttaaa taaaccatta
    19321 gagggagtta aggttattga cctaacgtat tttgtagcag gtccagggac ttctaaaata
    19381 ttagctgact ggggtgctga cgttattaag gtagagccaa gctttggaga cccaggaaga
    19441 aagacagggg caacaatgac aatgccaata gatgattata ataatccttt ttacagcaca
    19501 tataattcaa ataaaagagg tttgtctata aatcttaaga gtgaaactgg aattgaaatt
    19561 atggataagc ttttaagcga agcaaacgta tttgtttcaa gttatagaac aggagcatta
    19621 aaaagactag gtcttgatta tgaatcatta agtaaaaagc atccacacct tatctggggt
    19681 cagataaatg gttttggcga ttttggacct gctaaggata atgcaggatt tgatacagtt
    19741 gccttttggg caagaagtgg ggctatgctt gatatagcag aaaaagatac aagtccaata
    19801 aatccaccta tagcctttgg agatgcaaca acttcttgta gtttatctgg aggaatatgt
    19861 gcagctttgt accagcaagc taagactgga aaaggacaaa aagtaatggc atctttattt
    19921 gggcaagcaa tatggaatgc atcatcttta ttagcatcta cacagtttag tgatgagtat
    19981 ccaaaaacta gaaaaaatgc tatttcacca gtaataaatt cttatcgttg taaggatgga
    20041 aagtggatat tcttaagtat tttagagcat gaaagatatt ttgaggcact ttgtagatta
    20101 tttggaagag aagacttaat aaaagaagag aaatttgcat cttcagtaga aagtaagaaa
    20161 aatgctacag aacttattaa tattttagat ggtgaatttg caaagtttac tcaaaatgag
    20221 atggttgaaa aacttactgc tgctgatata gctcatgaaa aaattcaaca tgttaatgat
    20281 gtagtgactg atgaacaggc tattgctaat aactatatat atgaacatac aagtaaagat
    20341 ggaaataaga caatgcttgc atctactcca gttaaatttg gaaatattga agttaacatg
    20401 acttgtgatg ctccacttat aggagaacat tcagatgaga tattgagaga acttggatac
    20461 agtgattctg atatagagac tctaattgaa tctggaattg taacaatgaa taaagaagca
    20521 tgtgaaatat gttaataaac atgtgaagta tgttaataaa taggagggaa ttttatggat
    20581 tttagattaa cagaagcaca attaatgctt caaagagtag caaaagaatt tgcagagaat
    20641 gaaatagcac caatagctgc tgaaacagat aaaacaggta tttttccaag ggagcttttt
    20701 agcaaaatgg ctaaaatagg atttaatgga attggaacac ctgtagagta tagtggttct
    20761 ggtggggcag atatagaaaa ggtaattgtt gttactgaga ttgccaaaaa atgtgcagca
    20821 tctgcagcaa tattatcaat acacacaata tatgctcaag ctattttgaa atttggtact
    20881 gaggaacaaa agaaaaaata ccttccaatg atggctgaag gtgggtgtgt aggtgctttt
    20941 gccttaaccg aacctaatgc tggttcagat gctgcgagag ctgcaacaac tgcaattatt
    21001 gatgaagaaa ctgatgaata tgttttaaat ggaactaagt gttttatttc tggtggaggt
    21061 caagcagaat cattaataat atttgcattg acagacccat caaagggaat aaagggaatg
    21121 tctgctatca ttgtcgacaa aggtactcca ggtttttcaa taggaaaaat tgaagaaaaa
    21181 atgggtattc atggttcaga aactgcagag ttaatatttg ataactgtag agttccaaag
    21241 tctaacttat taggaaaaga aggtaaagga tttaatatag ctatgacttg tttagatgga
    21301 gcaagaattg gagttggagc tcaagctgta ggaattgctg aaggggcttt agaagaaagt
    21361 atcaaatatt ctaaagaaag agtccagttt ggcaagccaa tttcagcttt gcaaggtatt
    21421 caatggtata tagcagatat ggcgacaatg gtggaatcag caaaattatt agtatattat
    21481 gctgcagatt tgaaagctag aggagaaaaa cacactaaag aagctgctat ggcaaaatac
    21541 aatgcgtcac gtactgcaag agaggttaca aatttagccc ttcaaatcca tggtggatat
    21601 ggatatatga aggattatcc attagagaga atgtacagag atgccaaaat aacagaaatt
    21661 tacgaaggta cttcagaaat acacaaagtt gttatttcaa gagcagtact aggataggag
    21721 gaaaagaatg aatatagttg tttgcttaaa gcaagttcca gatactaatg aagttaaaat
    21781 aaataaagag acaggtactc taataagaga tggtgtacca agtataatca atccagatga
    21841 tagaaatgct ttagaagaag ctctaaaaat gaaagatgaa ctaggagcag tgattaaggt
    21901 tataagcatg ggacctcctc aagctaaaag tgctttaaaa gaagctttgg caatgggagc
    21961 tgatgaagct tatttaatct cagatagagc ttttggtggt tcagatactt gggctacatc
    22021 tacaattatt gctgctgcta tagagaaggt tggaaagtat gatgtaatat tctgcggaag
    22081 acaagctata gatggagata cagctcaggt tggaccagag gttgcagaat ttttagggat
    22141 accacaagtt acttatgcga aagaagtaaa ggttcaagat gacaaattac tagtaactcg
    22201 ttatacagag acaggggatt atttaataga agcaaagatg ccagttttat taactgctat
    22261 aaaagagtta aacaatccaa gatatccaag tgtcaaggga atcttagaag cttataataa
    22321 tggagatgca aagattactg tattaacact tgcagattta gatgttgata caactcaaat
    22381 tggattaaag ggttcaccta caaacgttta taagtctttt gtaccagtta aagacaagca
    22441 taatgaaata atagaaggta taaataaaaa agaaaaagct gagaaactaa tagaaatact
    22501 attcgatttg aaactagtat aggagtgtta agatgatgag agcaaaagtt aatcaaggta
    22561 taaatttaaa tgattataat ggtgtttggg taataggaga gcaaagggaa ggtaaaatta
    22621 atcctgttac gatagaactt attggtgaag gaagaaagct tgctgaccaa ttaggaaaag
    22681 agcttgcagt tgtgatagct ggatatgaag tagagaaaga agtgaaggaa ttacttcact
    22741 atagtgttga taaagtatat tacatcaatg accctcttct taaagatttc actactgatg
    22801 gatatgcaat ttcaattgca aatttaatcg aaagaaaaaa gccagaggtt gtattggttg
    22861 gtgctacttc tataggaaga gatatagcgc ctagaattgc aggtaaggtt ggaacaggtc
    22921 taactgctga ctgtacaaaa cttgaaatag attcaacaga taataagtta ttacaaacaa
    22981 gaccagcatt tggtggaaat ttaatggcca ctattgtttg tccaaaaaat agaccacaga
    23041 tgtcaacagt tcgtccagga gttatggcaa aagctgtaag aaacgaatca gagactggaa
    23101 ttttagaagt tgttactcca gaacttactg aaaaaatgat tagaactaga ttagtagaga
    23161 tacttccaca agaaaagaaa tctgtaaatc taactgatgc tagaataata gtatcagggg
    23221 gaagaggatt aaaaagagca gaaggatttg agcttataaa agaattggct gataaattgg
    23281 gggcagagat tggtgcttca agagcagcag tagattcagg gtggatagaa cattctcatc
    23341 aagtgggaca aacaggaact actgttagac cagaactata cattgcatgt ggaatatctg
    23401 gagcaataca acatttagca ggtatgagtg attctaaata tatagttgct ataaataaag
    23461 atgcaaaagc ccctattttt agtatatgtg actatggaat agtaggagat ttatatgaaa
    23521 ttatacctga aatgatagaa tcattaaata ggtaactttt agaaaacatt gaatatgtag
    23581 aatgataagt cttataatat tgtattgtaa gacttattat ttttgctgaa ggttatagtg
    23641 gggagatgaa acaatgaaag agcagtggta taaggatata tttgcaagag tattatctat
    23701 gactgatgat ggttttattg ttgtaaatac aagtggagta ataatagata ttaatgataa
    23761 atattgtgac tttttaggaa aagaaagaaa agatataata ggacaaaata tacaaagtat
    23821 tataccaaat acaaaaatgc tagatgttat gaaaaataag tattgtgaag aaggagctat
    23881 acatcattat tcaggtggaa atacaaaaga aaaaagtgta atagtaagta ggtcttatgt
    23941 ggaaaatgac aatggagaag tagttgcagg agtagctcaa gttaaattta gattgcaatc
    24001 atttgatgta gctaaaaagt taatgtcaga atatatggag ctccaatatt ataaagagca
    24061 gtttaaggat aactgtggtt ttgacaagct cataggtgaa aatagagact tcatagaact
    24121 taagaaaaca ggtgtgaaag cttctaaaac aaactttcca gtacttttaa cgggtgaaac
    24181 aggcacaggt aaagaagttt ttgctagagc aattcacaat aatagcagta ggtcagataa
    24241 acctatggtt agtataaatt gcgctgcaat accagaagaa ttattagagt cagagctatt
    24301 tggctatgac gaaggagctt ttacaggagc aaaaaagggt ggtaaaaaag gtaaattttt
    24361 agttgcgaat aatggtacaa tctttttaga cgagataggt gacatgcctt tgaccatgca
    24421 agcaaaactt ttaagagttc ttcaggaaag tgagatagaa ccagtgggag gtcttaaaac
    24481 tataaagata gatgtaagag taatctctgc cacaagaaag aatttaagta aaatggttga
    24541 agagggatta tttagagaag acctatacta tagattaaat gtaataaaca ttcatatgat
    24601 ggaattgaag gacaggcaag atgatatttt attgctagca aattatatat taaacaaatt
    24661 aaatgttgaa tacaaggaat tgaaggtttt aagtgataag gttaaaaatt gttttattaa
    24721 ctatacttgg ccgggaaata taagagaact acaaaatgta ataaaaagtg cctatgctgt
    24781 aagtgatgat atggtcatta tgatgtgtga ccttccatct aagatggata atatcagcag
    24841 agtagctcaa tgtaatgtgg atagcaattg ttcaattcat gaaatggttg agaattatga
    24901 aaagagctta attattgatg tgttaaggaa gtataattgg aaatgttcta aggcagcaga
    24961 ggttatggga atacacaaga gtcttttata taagaaaata aaaaagtatg aaattgaatt
    25021 aaataattaa gataacttga attaaggcaa tgctaaaaaa gcgcccttat tcaaagcgaa
    25081 ctgtataaac tgttttatgc agttaaaacg tgtaaaagta gatgtgaagt actaatgtca
    25141 atcattagta cttttttatt atatttataa ttactatcta tatttcagta tcttttgata
    25201 tctaagatta ttatgtttaa tttagtatat aacaaaaccc tcttagttat ggacagtttt
    25261 ttatatttta actgtctact aagaggggat agtttagttt aaatttagag taaattttat
    25321 ctagcattta taaaaaatat tttgaatagc ttttttgtta tttagtcata attttctact
    25381 tctttatcaa gttctttgcc acaagaatca cacttatata tagcattgta tccgtaatca
    25441 tattcatcaa ctattttctt ttgtctaaat acaccaccac actcacatag gaaaccaatt
    25501 tttataagtg taacgataaa ttgtgatttt ataaatttta tatcattgca tttatcgtta
    25561 gtgtaaaatg tataaatata agagttatcg cactcatctc ttaattcaaa tctttcaata
    25621 tatgtgttat tttttaattc ctcaaattct tctttagtta aatatgattt ttgttgcaat
    25681 tcatgtaaac gcttaatttg gtccattatt tatatcctcc caataatttt agtattttaa
    25741 gcttagataa ggaatctaag ttttattaaa tttatcccaa ggaattattt aaatcatatt
    25801 tagttttatt aattacaaca tatataaatt acacgaaaat aaaactaatt gtaaaaataa
    25861 tatcctgtga aaacctaaac tactaacccc ttactaaccc gaaaactaaa aaaagaaaat
    25921 atatccaaat ataagtga
//
LOCUS       DAEHWO010000052        24943 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEHWO010000052 DAEHWO010000000
VERSION     DAEHWO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24943
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.052"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(66..674)
                     /locus_tag="KNP54_002572"
     CDS             complement(66..674)
                     /locus_tag="KNP54_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBF0893449.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(783..3521)
                     /locus_tag="KNP54_002573"
     CDS             complement(783..3521)
                     /locus_tag="KNP54_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBF0893450.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLKDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3669..4460)
                     /locus_tag="KNP54_002574"
     CDS             complement(3669..4460)
                     /locus_tag="KNP54_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0893451.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4496..5152)
                     /locus_tag="KNP54_002575"
     CDS             complement(4496..5152)
                     /locus_tag="KNP54_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893452.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5145..6110)
                     /locus_tag="KNP54_002576"
     CDS             complement(5145..6110)
                     /locus_tag="KNP54_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBF0893453.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6216..6322)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6612..7556)
                     /locus_tag="KNP54_002577"
     CDS             complement(6612..7556)
                     /locus_tag="KNP54_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBF0893454.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7667..8134
                     /locus_tag="KNP54_002578"
     CDS             7667..8134
                     /locus_tag="KNP54_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893455.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNNDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8304..8903)
                     /locus_tag="KNP54_002579"
     CDS             complement(8304..8903)
                     /locus_tag="KNP54_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893456.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            9149..9745
                     /locus_tag="KNP54_002580"
     CDS             9149..9745
                     /locus_tag="KNP54_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBF0893457.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(9843..10802)
                     /locus_tag="KNP54_002581"
     CDS             complement(9843..10802)
                     /locus_tag="KNP54_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0893458.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(10836..11567)
                     /locus_tag="KNP54_002582"
     CDS             complement(10836..11567)
                     /locus_tag="KNP54_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893459.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNVYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(11560..12330)
                     /locus_tag="KNP54_002583"
     CDS             complement(11560..12330)
                     /locus_tag="KNP54_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893460.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGANKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(12415..13125)
                     /locus_tag="KNP54_002584"
     CDS             complement(12415..13125)
                     /locus_tag="KNP54_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBF0893461.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(13305..13457)
                     /locus_tag="KNP54_002585"
     CDS             complement(13305..13457)
                     /locus_tag="KNP54_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBF0893462.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(13483..15639)
                     /gene="feoB"
                     /locus_tag="KNP54_002586"
     CDS             complement(13483..15639)
                     /gene="feoB"
                     /locus_tag="KNP54_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBF0893463.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(15739..15960)
                     /locus_tag="KNP54_002587"
     CDS             complement(15739..15960)
                     /locus_tag="KNP54_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBF0893464.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(15973..16185)
                     /locus_tag="KNP54_002588"
     CDS             complement(15973..16185)
                     /locus_tag="KNP54_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBF0893465.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(16506..19403)
                     /locus_tag="KNP54_002589"
     CDS             complement(16506..19403)
                     /locus_tag="KNP54_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0893466.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDEESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKVKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(19730..20338)
                     /locus_tag="KNP54_002590"
     CDS             complement(19730..20338)
                     /locus_tag="KNP54_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBF0893467.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(20598..21143)
                     /locus_tag="KNP54_002591"
     CDS             complement(20598..21143)
                     /locus_tag="KNP54_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBF0893468.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(21261..23084)
                     /locus_tag="KNP54_002592"
     CDS             complement(21261..23084)
                     /locus_tag="KNP54_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893469.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRILNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSILLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(23097..24872)
                     /locus_tag="KNP54_002593"
     CDS             complement(23097..24872)
                     /locus_tag="KNP54_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893470.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         8217 a         4336 c         2445 g         9945 t
ORIGIN      
        1 aaaaaaataa gatacatacc tataaaatac cttcctatag atacatatct tacctatata
       61 aaaacttatt ctatataaaa acgccataaa aaatcttttg cttcttctgc ataatctata
      121 tttatacgtt tactagtttt tatatctaac tcatctttac taaatacttt ttttccttta
      181 tcatcataat aaaaatcact tatatataat tcttcaccca ttatactctt actatttaga
      241 cttctatcta tttttaaagc tttgcaaagt tttcctggtc cgttagtaat attttttact
      301 tgatatttac tcaactcagt gtaagctttg ttgtatctat tcatagatat ctcatctaaa
      361 gaagttatag gctctacccc tcttattaat acacactctg gcacattttc tatatttgca
      421 gataaattca agcaattata cataccataa attaaataaa catatatatg tccaccatct
      481 aaatataatg gcttagttct atctgtcttt ttattgccat atacatgtgc tcctttatca
      541 tttacaccca tgtatgcttc tgtctctatg attttggtaa caattacttt attttcatat
      601 ttccttatta gatatttacc taatattgat ttggctaaat caattccatt ttttctaaaa
      661 aaatcctttt ccaaaatttc acctcataaa atttatttaa aacgcatcaa atacaactaa
      721 agtaataaat aaaattaact cttattaatg tgatatatat aaacaataaa tttagacatt
      781 tattatttat atatatcaaa aaattctatc tcaaactttt caatattatc attgtaattt
      841 gaattatcat atacttcttc aacaacctct ttaattggga atataacttt tacattagtt
      901 ccttctccta ccttactatc tatgtaaatc ttcccatttt gaatttcaat caatgatttt
      961 gtaaggcata aacctatacc acttccaaat tcatttgata taccactgtt ttcaatttgt
     1021 ttaaatcgat taaatatatc ctttaatttt tctttgtcta tgcccactcc agtatctttt
     1081 ataattatct ctactgtttc gtctttttta tatataccta caaggatttc tcctccttct
     1141 aaagtaaatt ttatagcatt tgataatata tttagtatta ttctttctat cgattctggg
     1201 tcaagcccta ccataacagt ttcttcatct gtatcaaaaa ttaaatctat tcctttagac
     1261 ttagcataac tactaataga tgtaactatt ctttctgtta tgtcaataat atcaaaatta
     1321 actgctttaa tcttatatat gtctgactta acttgagaaa tatttattat attatctatt
     1381 aatctcaata atctaaacat attttgttta gttattttta tatgttcttt tagtatatcc
     1441 tgaaaatcaa ttatttttcc ttttttataa aggttttcaa taagttgaac tgaactatat
     1501 atattattta aaggtgtctt aagttcatga gatatattag cataaaactc catcttcatt
     1561 tggtcatact gtctttgttt tattaatgct tttttaagtc tttcagactc tctttgcaca
     1621 cttaaatctt taataattct cactctactt cttttctgtc caaagtataa tgttcttgat
     1681 atcattttta cttctttaat gtgattattt tcatttacta tatggatact cttctctctt
     1741 tctcctatat ttaaattgtt tatgtatttt tttactaata tatttctata tttttgtgtt
     1801 gtaactccta atacatcact agaaattccg aacaactctc taaaggctct atttgtatat
     1861 agtactcttg atgtacttaa atcctcaaga aaaatagcct ctggtataac atccagtaat
     1921 ttttcatata ttattttttg ttcatttact gttctaagaa tatttatctc tttagttata
     1981 tctctaaatg taagcaattt aaagagttta ttatctgacc aatagtctcc aactctaact
     2041 tcttcaacat gttcttcacc ttctgagtca gacatcacaa aattaactat acagtttgct
     2101 gtgtcattgt aacttactat ttcagctttc ttttcttgtg ttagatttaa tcttttaaat
     2161 tccctattgt caaagaaatc tatgttaaaa gtttcaaaat attgttctaa tgtcatatcg
     2221 actaaatcac ttgaaacaca tttaaaactc ttttcatatt ttttatttat acttattacc
     2281 ttattcttct ttatgccacc ttcagcactt cttacaagta taggagatgg aatatttagt
     2341 ataatgtttt catagtcttt atttatattt cttatttctt catctatttt gatttcattt
     2401 gtaatatcat ttaaacttat taagtaattg ctttcgtctt tattattact taaacttaac
     2461 aaataaattt tatcatttaa ctctaccagt ttatcaatta tacttatatc gttatcaaat
     2521 ttcttcaatt tttcagcaac tttttcatct tcctttataa aagttaatat tttataataa
     2581 ttattcatat cctttgaaaa ttcatcttta aatttattat ttgtgtaact tatattaaaa
     2641 tcatagtctg ttactatcca tacatttggt attgtatcca gagcttgtct aagtaattct
     2701 tttctctggt ctatgtagtt ttttaatgtt ctttgtataa tcatatcctt ttctattgct
     2761 aaatttatct ttcctaattg ctctgacttt ttacttaatt ttttattgat tgaatcaagt
     2821 tcataatatg gatacactac tctattatta agactgtata catatacata ataagtatgg
     2881 ttacataata gtaaatatat tactcctatt aatctatctg aatctactat attaatctta
     2941 gaaattgcta caaaacatat aatagttgta aaaaaaacaa aatatgttaa atcttttatt
     3001 aacttatagt gctcaatgtt actatcaagt ttattcaaca aatatagtaa attaaacata
     3061 gatatacaaa tattaattaa tataataatc atattccagt taatatcact aaaaatattt
     3121 cttataaagt aatctaatat cacaaaagca ctataaaaaa ttagtattgg gcttattctt
     3181 agttttttta ctttagaaat ggttaagtat ataaaagtag acatattaat tatgcttaag
     3241 ttaagcaata caatttggaa tttttgaatt tttaaattta ctactcctaa aatacttaca
     3301 aaaactaata caagacaccc tactttcaat atatttataa attcatctgt tttaaagcta
     3361 cttatataaa ctatagaata tccaaatatc caaagtaaaa ttattctata catatttata
     3421 gaaactgtat acaaatttat atttaaaagt gcaataacca aaaataaccc attagctagt
     3481 atatagacct tattcttact taaagttcct ttagattcca tattccccac cacttcttca
     3541 tttttatata gttttaccta taaatatgtt accacaattc ttccaaaaaa tttgtcactt
     3601 tctagttata aaaaaaaatg agtaaatatt tttaatttta ctcattttgt agattttgta
     3661 tattcagttt aaaaagctgg aactatactt cctttatatt catcttgtat aaatttttta
     3721 acttctttac tattcatagc ctctgataaa gccttaatct tatcactatc tttattattt
     3781 tctctacaag ctattatatt tacatatgga gaatcacttg attctattac tattgcatcc
     3841 ttagtaggat ttaagttagc tgttaaagca taattagaat ttattactgc tccgtcaaca
     3901 tcttttaata ctgttggtaa ttgctctgca ttcatttctt ttattactat atttttagga
     3961 tttttagtta tatctttttt agttataagc tctccatctt ttacttctat caatttattt
     4021 tttgctaata atttaagtgc tctagctcca ttagttgcat catttggcac agctataaca
     4081 gctccatctt ttaattcatc taatgactta actttttctg aatagaatcc cattggctct
     4141 atatgaactt tagatgtata agtaagttta tatcctttct ccttcacagt ttcctctaaa
     4201 aatggaatat gttgaaagaa gttagcatcc aaagaccctt catctaaagc tgtatttgga
     4261 agtacataat catcaaatat ttttacttct aaatcatatc ctttttcttt taacaaaggt
     4321 tttgcaactt ccaatatctt tgcatgtgga tttgatgaag ctcctactag tattttttta
     4381 tcctctttgt ttgaacaacc tactgctgat attgctattg ctgacaccaa tgctactgat
     4441 aataatttct ttaatttcat ttttactccc cctctttaaa atgtttataa ttaatttatt
     4501 ttagtttctt ataagccaga tttcctactc cctggattat ctgaactaat attataagtg
     4561 ctattacagt atataccatt actgctgtat caaatctttg atatccataa ataagtgcta
     4621 tattacctaa tcctccagct cctactgcac ctgccatagc tgtataacca agtatagata
     4681 ttattgataa tgtaattcca gatactattg aaggcatagc ttcctttatc ataactttaa
     4741 atactatttg tctttttgta gctccaaaag attttgctgc ttctatcaat cctttatcaa
     4801 cttcatttaa tgagctttct ataattctag cgataaacgg tgctgcccca atagttattg
     4861 gcactattgc agcagtttcc cctatacttg ttccaacgat taatctagtt attggaatca
     4921 ttgcaactat aagtatcata aatgggaaac ttctaaatat atttactata aatcctaatg
     4981 cactatttat tgtgctattt ggttttaatc catctggttt tgtaactact aatatgattg
     5041 ctaatataaa tcctaatatt gttgccacta tagttggtac tataaccata tacaaagttt
     5101 gtaacaatgc atttggaaat agtgttgtta aaaagtcaat taaactattc atttatcatt
     5161 tcctcccatc ttatgccctt actagttaga tattgtttta cttgctctcc acttttatct
     5221 gaaatgttta taataagtga acctaaaata tcatctttaa attgttctaa tttcccaaat
     5281 attatagaca catctatatt tagttctctt gccatagtcg taataatagc ttcattagaa
     5341 atatctttag ggaatagtat ctttatattt gttccttttg gcaatattat actttcttca
     5401 cctattaatt ttctaagtcc tttagtattt cttaagaata tttcttctgt atctcctacc
     5461 tctaatactt ctccattttc cattattgct actcttccac aaatctgctt tataacttcc
     5521 atttgatgag ttacaactat tattgttatt cccaattttt tatttatatc ttcaagcaat
     5581 gaaagaattg actttgtagt atttgggtct aatgctgaag tcgcttcatc acaaagaagt
     5641 acttgtggat ttagtgctaa agctctagca attgcaaccc tttgtttttg tccgccactt
     5701 agatttctgg gtttatcatt tttcttttca gatattccaa ctacttctaa taactctaaa
     5761 actctttttt taatttctgc ctttgagtat ccaaaacatt ctaatggcaa tgctacatta
     5821 tcaaatacag tttttctttc aagcaatgaa aagtgttgaa aaatcattcc taactctttt
     5881 cttaaatctc tcatttgctt ttcattcaat gactttactt ctttatcaga aacaagtaca
     5941 ctgccttctt ggtattcttc taatccgttt atacatctca gtagtgttga tttccctgca
     6001 ccactatgac ctattattcc aaaaatttct ccagattcta tttcaatact tacatcttta
     6061 agcacttgaa tctttccata atacttatta acatttttta tgctaatcat aaaatttcct
     6121 cccatatatt ctgctcagtt tttatgttta tcctctctta tgtattacaa caaaataaaa
     6181 gcccgagtat aaactcaggc ttagaaagct atttatactc atctatcaac tatattagtt
     6241 gcaggattta gcaccaatgt atataaaata tactggttgc cgggtttcaa agggccagtc
     6301 cctccaccac tcttgataag acgttattta atttaattct attatcattt gttgctatgt
     6361 tatatatgat atattcatta atagtatttg tcaataaatt tatttaaatt ttttattttt
     6421 tattatcgtt aattaactat ttttaattag ttttctagct cctaacactt tatattttaa
     6481 tgtctatata actatagaac atcattataa gaaataaatt aaataacatc aatctatcta
     6541 aatcatctgt aaagtaaatt aagaaaatta acattttatc caaactctat cctactatta
     6601 aataaaataa tttaaataca atgatgatta tatagctcta gtactttaga ctttatcaaa
     6661 tgtttaagtt ctataggttc tattattgta gcatttttcc caaaagttaa aaaatattca
     6721 gccacccagt taagtgtaga ttttggtata tacatatcta tgtatccacc tttagacaag
     6781 attttcaacc ctcttgccaa caaaaattct gtttcacaac gttttactcc ctcatctgtc
     6841 aaattaattt taatatgata atctgtacct acttccatat tcttaagata atcatgtata
     6901 gaagataaaa ccttatattt cttacttgat aagttttcta tactcaaaat cttcacaatt
     6961 ctgtctacac gaaattcctt aatagattct gattttatac agtaagctgg acaataccaa
     7021 agtccattca tggcatacaa accaatagga acaatggtac gtacactatt tttttgcttt
     7081 gatgaatatt caattttaat tgtaaattca ttcattacta tattaaacaa ttctttcaat
     7141 aatggtgttg aacagtgcct atctggtgtc caaaaaacaa atttacgcct tatattctca
     7201 atattatatt gaatatcatt tggtatacaa tttaaaaatt tttttaaaac agaaatagtt
     7261 tcttgctcaa atggcaaatc attataatat tctagtgact gatatgcaaa gaatatagat
     7321 tttacctcac tttctgaaaa tgcaatcggt ggaagtatac gctctttaag tacatgatat
     7381 ccaccagccg ctccaacttt tgaatataat ggaaatccaa tactctccag cacctgtaaa
     7441 tctcttagta tagtacgttt tgatacagaa aattcttctg ctaattctcc tgctgtaaaa
     7501 cttctttttg catttattgt tatcatcagt tcaattaaac gctcagctct tgacatattt
     7561 atactcctaa tttaaatata gtgacaataa ttgtcactat tatatgataa gatattcttg
     7621 catctaaagc aataataata gtaaagaaag aagggattga tactttatgg aaaatgatac
     7681 tattaaggct gatgatattc tcaattattg tctatcaaac ttagatgatg ttgtactaat
     7741 ggatagttgg ggggaacgag caatttacta caatcctaat ggtgttttaa agcgaggggt
     7801 atatgttctt accattaagg aaaaagacag taataatgat aaaggttcgt tagttagtcg
     7861 tccaaatgta taccgtgtga atataggatt aaaaaaagaa acttttattg aaatgtttgg
     7921 atatattcca aagcgtccag gtgtaggtca aatagttgat atggattttg attttacaaa
     7981 attggacaca atcatgccac atcctatcta ctcatggatg ggatggatat gtgtcctaag
     8041 ccctactgaa aagacatttg agaactttaa aactttaata ggagaatctt acaattttgc
     8101 aaaacaaaaa tttaaaaaga gaaaaaacaa gtaaaaacgt gtgaaaataa cctctaaata
     8161 aattataata aaaatattaa ggttacaaga taaaaattaa tatcttaata acatgcaaaa
     8221 aagcgaagcc aaaaaatgta ttatttataa ggcttcgcta tatctcaaat aatttatttc
     8281 aaatttcaaa actatttatt ctattatttc ttattatttc ctgttattcc taatctatca
     8341 ttcatatctt ttatcatttt tctaaaacca ctacctatat catttccaac atcttcagtt
     8401 ccatgaacta attttataaa gtcattttga ccttttttca tatcttcatc agatacctta
     8461 tctaattttt ctattctctt atctatatct tttactaatc tttccccttc agcgattagg
     8521 tcatcattca ttttctttaa ctctgtatct tctgttttac catctttttt aagagatgtt
     8581 acaaatgatt gtattttatc tctactatct ttatatgcag cctttacatc acttagatat
     8641 ttttcatttc ctggatattc tttatcttta aactgattat ttatactttc tggagtatca
     8701 taaatagaat atctatttag acctgctata taatcattat agcttgttga ataataattc
     8761 atatatcctt cattattatt tacagattca ttaggatttt ttcctgtatt ttcacttggt
     8821 ttttcattat ttttagtaca tgcagttata cctatagcta atactagtgc taatcctaca
     8881 aataaagttc tttttaattt catttttatt accctcctag atgttttata ctataaaaaa
     8941 ttttaataat tttctttctt aatttagtat ttctatattt ttatatttta tttactaaaa
     9001 ttaaacaagt tataatttat ttttttggaa atcataatga ataaataatt aaataaaaaa
     9061 attataattt tatcattgat attgattatc attcatagta taatctaatt acttgatatt
     9121 aattttcatt tgaaggaggt tatcttttat gtcttgttgt aattcacaat tttgttgtaa
     9181 aaataaaatt gaatcatcat atataaaatg gcttttagaa gttttaggtc cagtcttttt
     9241 aggctctaaa cctgctgaaa taataaatat ttcgtttact gatgtaaata gagaggaaaa
     9301 aattaatgat atttataaat atctatataa gtgtaagaaa atagatttta tagttattga
     9361 taaagaaaaa aagggattaa aaatcttatt tgtaaataaa aaagcattat cagaaaaatt
     9421 aaaatgtaaa aaaacagtaa actttttaaa gtttttagga tacaaacaaa atacgaatgt
     9481 taatgcttat ttagagcatt tagtagataa acttaagagt gatgtttttc ctgatgaaat
     9541 aggtattttt ttaggatatc ctcttaaaga tgtgattgga tttatgggat atagtaatta
     9601 tgaagtttct atgattaaat attggaaagt ttatggtgac acaaaacaat ccgaggacac
     9661 atattcgaag tttttacttc accgtaagaa aatgagaaaa ttactagact acataagtgt
     9721 agataaaata gtaagctgtt tttaattgtg tttttgtata ataataaaaa tacaccctct
     9781 tttaccatac agtttccata ataaataagg gtgtattttc cactttaata ttttaaagta
     9841 ttctaatttt gattgtacaa catatcttta atatttattt tcttttgttg cattccatta
     9901 gacatcaaaa attcctgtgt atcttctaat tcttttatat ccttgtccgt tattttagaa
     9961 ctaaagtcat accaagaata catttctttt gtttcatcta aagataaacc aacttcttta
    10021 gatacaacat ccatcacttc atccttgttt tcattcatat attttaaagt ttcttcatga
    10081 accttcataa atctttttac taattcagga tatttttcag caaagtcatc acttacagca
    10141 gtaactatta ttccacttac taatccttct ccatttacaa tcattttggc acctgaattt
    10201 atcgttttca atgccactgg acctgcaagc attgctacat cagcactttt actttctaat
    10261 gcagaagcag cactaggaat atccatattt acatattcaa catcatctat agtatagcct
    10321 tctttagcaa gtgcagcaat caacagttga tgaagtatag tcccttttgg acctacaatt
    10381 tttttacctt ttaagtcttt tatagattta atattatcat tattagttat aagcatatat
    10441 ccttttggtg aacggctata aatattcgta attttaagac caacaccatt tgatgcagct
    10501 attattgcag acgttcctcc taatgcatgt aaaaagtcta gctcacctgc tgctaatgct
    10561 tgagtttgct ctggtcctgt tgtcaattca tggaaattga cttttatatt gtccttttta
    10621 aattcctttc caaataaatc atcctttttt tctaatatac taggaacatt aagtggtgat
    10681 tttacataag ttaaatttat ttccttaggt aaactagcct ctttttttgc aggttcatct
    10741 ttcttatcat ttgttgttga acatcctaca gtcccaacca acaccattat taaagatgtc
    10801 attactgcta aaatcttttt gtttctttta atcaattaaa actcccccaa ttcccttaat
    10861 atttcttttt tcaagtttat ataatagttt ttagttaaat ctctattata ttcatcttcg
    10921 acactaaatt gtttaatcct tttattttta ctaaaaacaa ttattttctt tgctatttcc
    10981 atagcttctt caatattgtg agttacaaat actacacctt ttttagtatt tttatggata
    11041 tttacaactt ctttttgcat ttttcttctt gtgaagtaat ctagtgctgc aaatggttcg
    11101 tccatcagca aaatatcggg attgaaggaa agtgctcttg ctatacttac tctgtgagcc
    11161 attcctcctg ataattcatt tggatatgag tttttaaact tttcaagctt catcattttt
    11221 aaatacttgt ctaaatcaac tttatttcta ttatcttttt cagtatgtaa aagtatattt
    11281 tcacttacat tcagccatgg cataagtcta ctttcttgaa ataccattcc tacttttgga
    11341 gtacactttt tatcattatt aaaaaaatat acgtttccac tagtagcatt ttcaagccct
    11401 gctaaaattc taagtagcgt tgttttccca catccacttt cacctaatat aacagttatc
    11461 tcttcactag atatatttaa agatatatta tcaagaacta aatgctcttt attatcaact
    11521 aaatatttct tatatatatt ctctagcaaa aatccacttc taaccattta aatcaacctg
    11581 cttccctttg ctaaattttg ttattatctt tgaaaataga taatctgaaa gtatacctaa
    11641 aaatccaata acaaaaattc ctaccaatac aacatcagtt ctagacatat cttttccatc
    11701 agaaatcaaa tatcctagtc ctgaagaagc tgcaataagc tctgctccaa ttatagccct
    11761 aaaactatac ccaagcccta aactaagtcc aacaacaata tccagcatag aattagggat
    11821 tattatttta taaaaaattc tctttttaga taaattaaaa gatttaccta cttctattaa
    11881 tttattgtca caatttttta tacctttcaa tgtatttaaa aatattggaa aaaaggatgc
    11941 caaaataata attataattt tagattcttc acctatacca aaccataaaa taagcattgg
    12001 caccaaagct agtggaggtg tacttcgcat aaattcaaat agtggtttga aatattcata
    12061 cattttttta tttgctccaa ataaaactcc aagtggtata gccatcaatg aacttattaa
    12121 aaaacctatt aatatccttc ttacactggc ataaacattt aagaaaatag aaccgtcata
    12181 tatcattttt ataaaagtat ctaagactat ttcaggagga ggcagaatat agctactcca
    12241 tatacccaaa acacatacta tcttccataa aattaaaatt attaaaaaaa tataatatcc
    12301 tttaagcctt ttatgaattt tctcaaacat ataaaactcc ttttaacata tctatccctg
    12361 ctaccctttt tattttttaa tatcttaaat aataattaag ctatatcata agatttaatc
    12421 tatgccaagt cttaatccac ctgaactcat tctatcagaa ggtgtagaat ctgtttttaa
    12481 gccagacaat ctttcagatg gttgtataat gactatttgt ccaggttcaa caaattccat
    12541 atgataagat tctcctgaag tctgaccaat aaaagtcttc catgatagtt ttgatacttt
    12601 aggatatggt tctcttccag tccaagctac taatgcatct gggtcaacac aacaaggtcc
    12661 ttcaagaatt agaggattac catctgttat tatagcaaca tcttgatttt gacctgtttt
    12721 atttactaaa tgtgtagtaa aaagaccttt ttgagatatt acccctgaac caatcaattt
    12781 tacactgtaa tttaattgtt cagaaaatgc caataagttt tcactctcaa cataaatgga
    12841 atcacctggg tcaattgata ttacatctac atggtaagca ttttgagcta ggtaaatttc
    12901 accttcacct tcaaccacca ttattggcat ttgttctcct gtcaatgacc tctgaacatg
    12961 acctaataat gctcttccca atccaccgcc attacttgga cctaacagca atttttcaaa
    13021 attaaaattt cctttaaagg ctaccatagc accttttttt gcaaaaaatt taccacttcc
    13081 ccttgctata cacataagct cgtttgtaac atcaaattta aacataatat tcacttatat
    13141 tgcttaattt agcaataatc cctcctaatc atatatttat atataattat acagtaaaat
    13201 tacagcatag tctaacctac ttcaaatatg aaatttgtta tttatacaaa aaataagaac
    13261 ctgataataa agcaatttaa ctttttatca ggctcttatc ctatttatct cttagcgcta
    13321 tgacaactct tactacttga gcatccagaa caaccacatc cacaactgct accattcttt
    13381 tttgaatttt taaccatata cattacagct agtgccatta atactactac aatagctgct
    13441 ataataaatg tagccatatt catcactcct tatttatatg aattaatttt tcatataact
    13501 taatttaccc attttttctt ttttcatatt tttatttgaa taagttaaaa ctacaaagac
    13561 tactgctact gctataaata tagatattat tgccccagca atacttcctc cagtacctaa
    13621 aactaaactt ccaacttgat ttataagaag agcaattata tacgctgtta aagtttggaa
    13681 tcctaatgta atccatgtcc atttccatga acccatttct ctttttatgg ctccaatagc
    13741 tgcaaaacaa ggtgcacaaa gcatattaaa tgccataaat gcaaacgcac tagctactgt
    13801 aaacatactt gcaactgaag caagaagtgt tgggtcttgc tctgttgcat ctgatatacc
    13861 aaataaaact ccaaatgttc caactacatt ttccttagct actagacctg taactgttgc
    13921 tactgatgat tgccaatttc caaatccaag aggagcaaat attggtgcaa ctatatttcc
    13981 taagctagct aatatactat ctccagcatc taccatttgt aatgaccaat taaatgattg
    14041 taagaaccag attactccac aagcaacaaa tataattgtt cctgctttga ttataaatgc
    14101 ttttcctcta tcccacatat gtattaaaac accttttgca cttggaatat gatattgagg
    14161 taattccata acaaatggag atggttctcc tgcaaataaa ctagttttct ttaatataat
    14221 tccacaaatg attatcattg caatacctaa gaaatacatt gatggagcta cccatgaagc
    14281 acctccaaat aatgcccctg caaataatgc tattattgga atcttagctc cacatggaat
    14341 gaatgtagtt aacataatag tcatttttct atctctatca ttctctatag tacgagttga
    14401 cataactcct ggaactccac aacctgaact tataagcatt ggtataaatg attttcctga
    14461 aagaccaaac ttacggaaaa ttctatccat tataaaagct acacgtgaca tgtacccaca
    14521 atcttctaat attgataata ataagaataa aagcatgatt tgtggtacaa atcctagtac
    14581 tgctccaact ccaccaatta gaccatcaac tacaagtcct tgtaaccact ctgctacatt
    14641 taaagaagct agaaaattac ttacattgcc ttgaataatt tctccaaaca gtacatcatt
    14701 tgtccaatca gttgctatag tacccaatga acttactgct atatagtaaa ctccccacat
    14761 tataagtgca aaaataggta atgctagtat acgatttgtt acaatcttat ctatcttatc
    14821 tgatacagtt tccttacctt ttcgattctt ctttattata cttgaaatta ttgaactaat
    14881 aaattcataa cgattggctg ttattatact ttcactatca tcatccaatt catcttcaca
    14941 atttctagtt atttcttcaa tactattcaa tattgtttta gaaatatcaa gtttttgtat
    15001 aacattttca tctctctcaa atagctttat agctaaccag cgtgtttcta catctatata
    15061 tggagtcttt tcttctatta ttttttcaat tttttctatt gcatccttac tttcatcaac
    15121 aaagggtaat ttgaaattta atttattgtt actacttgca agttcaactg ccttttcagc
    15181 agcctccata attccttgac ctttaactgc tgttacttct accactgggc aacctataac
    15241 ttcagatagt tctttaatat ttatcttatc accattctta tttacaatat ccatcatatt
    15301 aagagctata acggtcggta tacctagctc taaaacttga gttgtaagat ataaatttct
    15361 ctctatattt gatgcatcta caatatttat tactgcatcc ggcttatcat ctagcataaa
    15421 attacgtgta actacttctt ctaatgtata tggagataaa gaataaatac ctggtaaatc
    15481 tactatttcc acatctttat ttccttttaa ttttccacct tttttttcga ctgttactcc
    15541 tggccagtta ccaacatatt gtgatgagcc tgtaagccca ttgaacattg ttgtcttacc
    15601 acagttagga tttcctatga gacctatttt tattgacatt tccattccct ccattattat
    15661 ttaaatacat cactgtttgt gatacagaaa atcattctca ttatataatt acattaaccc
    15721 tactctaatt aatctttatt attccacaat aattttttct gcatctgact tacgaattga
    15781 tagttcataa tctctgactg ttacctcaat tgggtcacca agaggagcta cttttcttat
    15841 aaatatatta acacctcttg taatccccat atccattata cgtcttcgtg tagctccttc
    15901 tccctctaac tttttgactt ttacagtctc tccacactta atatccttca gtctgttcat
    15961 gtcattacct ccctatatta ttattctact tgccattttt ttatctaatg caactctagt
    16021 atcttttacg tctattatta agttaccatc tatcttagaa actattttaa catttgtacc
    16081 cactacaaaa cctatactat ttaaaaaagt cctcgtctta tcacttcccg aaattttctt
    16141 tataactact tcttcacctg tatttgataa tatcaatggc atcatataat atccctcctc
    16201 ttaaagtaat ttaaatctac aagcaatcgt tatcttatat ataaattaca ataccttaaa
    16261 tcttaatcta ttaaaataac atcctatttt ttccttcttt ttacaattcc taattttgat
    16321 ttaagtctat cacaatagta tattttttgc aagtgattat tgtattcttt tgattttttt
    16381 tctcatttga tttattttat taataaaatc gtaaaaatta atacaaaaat aaagatgctc
    16441 taaaatagta tactcaacta atattaaagc acctttatta tatatgtcat tatttacaca
    16501 ttgctttatt cttttttaaa agcgattttt tcaaactctt ttacaggcat tggcttagaa
    16561 aacaaatatc cttgtaccat atcacaccca atttgcttta gaaattctac ttgcgaaata
    16621 gtctctacac cttctgatat tactttcatt ttcagttcct ttgccatttt aatgacatta
    16681 gatataacaa ttttttcatt attactctca tctttttctg taaaaaatgc tctatctagt
    16741 tttaatatgt caacaggcaa ttcttttaaa agattaagag aggaatatcc tgtaccaaaa
    16801 tcgtccatag agattacaaa tcccttttct ttcaaattgt tcattgtatc aagtaatcct
    16861 tctatattat ctaatactgc tgtttctgtt agctctaatt ctataagtct tgtcggaatt
    16921 ttgtatttat ctacaattaa tttaaactcc tctataaaat tactatttac aaaatgcatt
    16981 cgagacaagt ttacagatat aggtactact ttttgtcctt catccatcca ttctctaatc
    17041 tttttacaca cttcctcaaa tacatagaaa tcaatattta caataaaacc attcctctca
    17101 aatacaggaa taaattctat tggtggtatt agaccttttt gtggattatc ccaacgaaca
    17161 agagcctctg cccctataat ttgataatct gaaaggctat atttaggttg aaaataaaca
    17221 ataaattctc cattattaag agcatctacc attgaatttt caatttcttt ctcttttaat
    17281 atttttttgt gcatttcctt atcgtaaaaa gcaaatgaat ttttatgacc accttttata
    17341 gtttttcttg cagtattagc tctatccata atagtattta tgtcattatc acttttactt
    17401 attttatata taccacaatc taaaatcaat ttataatagt ttattttagg attactaagt
    17461 atttgaacct tattgtaaat attgtttaac cttgttttaa tatcatcatc tgtcttatac
    17521 ttaataagaa gaacaaaatg gtcagcagaa actcttgcaa aaatttcatc ttcctttaat
    17581 tcacttgcaa tagtatttga tatatgtatc aaagtatcat ttcccatatc atatccaaac
    17641 atatcattta tatatttaaa tttgtcaaca tctatataaa acaacgcata ttcttctgga
    17701 ttattcttag caaacagttt attagaattt attttaaatt tatctatact atctgctcct
    17761 gtcaatgggt ctgtatatgc tatcttcctt agataatcct ctttcttctt tttattataa
    17821 attatatatt taatagcaat taagaataaa atacatacaa aagaaataat ttgtattgaa
    17881 tattctttaa aaatcacacc aaatggtact ttataaggtt tgtcaatagt attagaatat
    17941 atacaatcac ttaattcttc ttcagtaatt ttgtctattg atttatttaa aatagacact
    18001 aatatagggt cagttttatt tgatacccct atacgcatcc catagcttgt atctaaaaca
    18061 gatataacag ataaattctc actctttcct tctcttaaaa gttcatcaaa ctgataagaa
    18121 ctaagtatca ttaagtttgc tttaccttca tttatagcgt ttagacaact ttctacactc
    18181 ttataagatg ttgtcttagc attttcaaaa ctcttttcta tataagaatc aatagactta
    18241 taactactag ttaaagcaat atttaaatca ttattgagat tggtatccaa ttttcctacc
    18301 ataatcattg gaatatttat gtatggattt gtcaatttca tattaaatcg ttttacctta
    18361 tcattttcat tgattgagcc acatagcata gttgccttac cactttttat gtaatcaaga
    18421 ctctcattat aattttttgt tttaatatat tcaaatttta taccacattt ttttgatata
    18481 attgacatta aatcggaact tataccttta aatgaattgc tttcttcatc ataatactct
    18541 acaggagacc actctgaatc atataccata gtaagttttg ggtttgcttt aataaaattc
    18601 atttcttgcc gagtaaatgc tatggaatta ttgacctctc ttttgaaata ttttttatat
    18661 aattccaact cataatacat atcatttatt tttaattctt ttaaagcata atctaattct
    18721 tttactaaat taggtttatc ttttgcagta gcaaaataaa aaggttctac tgaaaatttg
    18781 ctaactattt tcattccttt agcatttata atacttccac aaacaaatgc atctgccttt
    18841 ttttcattga cggactcaat taattcatca atagaattac agtatatata ttcaactgaa
    18901 aaattatttt cttctctata cttctcaaat gcagtattat gaaagtttcc tctaagtaca
    18961 gctactctca ttcccttaaa ggaacttata tcttcataaa acatattatt gttactatcc
    19021 tttgtatata gtgcactata ttcatatcct gaacttagtt taggaaaatt aaatagttta
    19081 tttctttcat cattcttctg taaaggtccg agtaagtcta tttcaccctt ttctagtctg
    19141 tctaaacatt cttcccaaga cccttttaca aattcatatt cccatcttgt atattttgag
    19201 atttctctta gataatcata accatatcct gtataagaat gctcttttga tgaggatatt
    19261 attccgtagt catcacaata tccaactctt attttttttg aattttcaga ctcatcagca
    19321 aagcatagta tattgttaaa acatgatata ataagtaaaa atatcaaaga aagtatcaag
    19381 aagtgctttt taaatgcttt catatttaaa aacctccaat ttgccaactt actttaactt
    19441 atttcgtttt ctagttgtaa ctacttttat tgtaatggta aatatatcaa attgcaatat
    19501 tctcatataa tattcttatt caactataat gaatttatta ttatctattt aaatacacta
    19561 tctaatatta gtttcttata agtcataaaa gcacaactaa cactataatt ctagtgatta
    19621 attttatttc aaaaaatata ataacactac taatatttta aatatcaata gtgtcataaa
    19681 aacttttcag attaattaaa tctttctata tattttataa taatctaaat catgctaaat
    19741 atttagacag aaaacttttt tctttaatag taaatacttt tgtttgaata tcagaataat
    19801 tatttgaata tctatctata aaaccatgat ttgcatctaa aatctcaatt tggatatttt
    19861 gtttcctaga aagttggtaa gaaatagaat caacatcaaa tgaatcgtgc tttgcaaata
    19921 ctaataaggt aggacatttt ggaattacat ccatgtaatc tctaatccga gagccataac
    19981 aacaaattat gccatcacaa aaagaatctt cactgcatct ccatgcaata gttgctccca
    20041 cgctataccc agcaacaaat acatatttat actctgattt taaatcattt ataagctttt
    20101 caactttttt ataaatatca aaaccaacat tatttataaa aaaatcatat gcctcttgga
    20161 cttttgaata tggaaaaact cttttttctc ccagaagttc aggacaaaat acatcatatc
    20221 catatttata atacttttga caaacatctt ctataaagct attaatccca tagatttcat
    20281 gcaaaacaac aatagctaca tcacttttat gtatatactt tatcagatta tccaccacct
    20341 ttacaaaaca gcaaattttt tatacttagt ttaatatatt cttctttaca tgtcaattta
    20401 cttttctaaa atcaaattta tttttggatt aatcatttat ttttaaaagt tgtgcattat
    20461 tactattaaa ttattctcta ttattaaaaa tataatcgtt agaaataaaa aataaagtac
    20521 aaataattaa aaaatatctc actcataact ttaaaaatta taagtgagat actcctaaaa
    20581 tctactttat attaaattta ttttccaaaa tatctattta ataatcctaa aaatgcttta
    20641 ccatgtctag cttcatcttt acacatttca tgtactgtat catgtatagc atctaatcct
    20701 aattcttttg ctttcttagc taattttaat tttccatcag ttgcaccata ctcagcatca
    20761 actctaactc ttaagttttc ttttgtatct gcaactacaa cttctccaag aagttctgca
    20821 aatttagcag catgttcagc ttcttcaaga gctattctct tataagcttc tcctacttct
    20881 ggataacctt ctctatcagc ttgtctactc attgctaaat acattcctac ttctgtacac
    20941 tcaccaacaa agttagctct taatccttcg attatttctt catctacacc ttgagctact
    21001 cctattctgt gctcatcagc ccaatttttt tcgcctttca tttcttcaaa tttatcagct
    21061 ccaactttac atactggaca ttgtgctggt gcagcatctc cttcatgtat atatccacat
    21121 actgtacaaa caaatttctt cataattact ttcctcctaa attttatata tcaaattaaa
    21181 ttttttattt attaagttag tctatatata cccgcaccat atacctttaa acaatttttt
    21241 taaaagtttt ttctaaatac ttattttccc tgtgtcaata atatgtttct ataataatgt
    21301 ccctttaatt ttatcaattc tttatgattt cctgattcca caattctacc attttctaaa
    21361 actattatat tatcacaatt tgatatggta cttaatctat gagctataat tatacttgtc
    21421 tttccataag ttaaattatt tattgcttct tgaattttag cttctgttgc tatatctatg
    21481 ttacttgtag cctcatccaa aataagtatt ggagcatttt ttaatactgc tctagcaata
    21541 cttattaatt gtttttgacc ttcacttaaa tcttcacccc tatccgataa tacagtacta
    21601 tatccttcac gcattttaac tataaattta tgtgcatttg ctattttact agcatatata
    21661 acttcttcat cagtagcctc cagatttcca taccttatat tttccataac tgtatcattg
    21721 aatatataac cttcttgtgg aactactcca aaacaagttc tcaaatagtt tctgttaata
    21781 gagtatatat ccttaccatc taaaagtata cttccttcat ctatatgata aaaatttgta
    21841 attagattta taatagttgt ttttccactt cccgtctctc ctatgatggc atttgatgtg
    21901 ccagctttga tttttaggtt tatattatct aaaattttct tttttgaatc ataagaaaaa
    21961 cttacatctt taagctcaat ttctcccttt acaaaatgag agtttaaatt accatcttta
    22021 ttatcgttaa tctcactttt aaacatgtta tgcacttctt gctcttcttg ttcatctata
    22081 atttcaaaaa ctctttcaca tccagctatg gctgaaagta atgtattaaa tagatttgct
    22141 aattcattta aaggtcttgt aaattgtctt acataactta aaaaactagc tataacccct
    22201 atggttataa tatctttaga tgcaagaatg cctcctataa tacatatagt tgcaaatcct
    22261 atattactaa tcacattcat aataggcatt aaaagagaag tgtaaatttg cgatttaagg
    22321 gaaatattta gaattctatc attgacttct ttaaaatcat ttacagattt tctttcataa
    22381 ttaaaagatt ttactacatt tatgtttgat atcatttctt caatatgtgc atttagtttt
    22441 cccaactcaa cttgttgttg cttaaaaaaa actctagttc tctttgcaat aaaattactc
    22501 acaaacatta ctatcggtat taatattaca ctgcaaaagg ttaaaattgg gcttaataca
    22561 aacatcataa taaaagtcat caatatgttt aagattcctg taattaactg tactaatgaa
    22621 tttgatattc ctgtactgat attatcaaca tcatttgtca ctctactcat aatatctcca
    22681 gtagaacttt tatcaaaaaa ggttattggt agatttttaa attttaaaaa taaattactt
    22741 ctcatttctt taactatact ttgagataat ctagctgtac atatcccctt agacagttta
    22801 actgaaaact caattatata aaatgaaagt aaaataatta ttccttttaa gaaaatggat
    22861 tttgaataag tatcgatatc tattatgtca actacctttc caatagtata tggtattaca
    22921 gttgatataa ttgaatcaat tattactagc aaaaaaataa atctagtaat cttcttatct
    22981 tttttaaagt acataaaaat tcttttaaac gtttttttaa aatctttagg cttttctttt
    23041 ttctttaatc tactgacctt ctgatttcca gtacttaaat tcaatatact tcctccttaa
    23101 tttacatctt cacttactaa attctgcaac gcaaaaattt ttttataaat tggagaacta
    23161 accagtaaat cttcatgtgt agcaaatcca accacctcac cctcatccaa gactaaaatc
    23221 ttatcacagt caattataga actaatcttt tgtgaaatag ttattacagt acatttctta
    23281 ctttcctttt ctcttaaatt acttatatac tcttttatat tctttcttat aattgtctct
    23341 gtattaatat ccattgcact aaaacaatca tcaagaatta atatttgtgg ttttttggct
    23401 atagctctag ctatagtaat tctttgtctc tgtcctcctg ataaattttt acccctttgg
    23461 aataaaactt catcataagt attttcgagt tttgttataa attgatttgc atttgctatt
    23521 tcacatgatt ttacaacatc ctctttgcat atatctctat ttcccataac tacattctcc
    23581 aatatacttt ttccaaacac actactattt tgaaatacta cacctattct tgcccttaaa
    23641 ctttcttcag aaatactgta tatactacgt cctccaatct taatatcacc tttatcaatt
    23701 atatataatt tttgaattaa atttactaaa gaagtctttc ctgaaccagt ttgaccaatc
    23761 acaccaatat tttgaccttc ttctatttta aaggatacgt tttttaatat tttttcatct
    23821 gtatttttgt tatacgaaaa atctacattt tcaaaaatta tatcacagtt tacaaacttt
    23881 aaatcttttt ctccaacatc taaactttct tctctctcaa ttacttcttc attctcatca
    23941 accaaaacct cacttattct ctcataagat gcttttgccc taacaaaaac attaaaaaca
    24001 tgtgaaatca ttataagaga tgttaatatt ctagtcatat agtttacata agcaactata
    24061 atcccaattt taatttctcc tgaataaatt aaatgccttc caattagtaa tattattatt
    24121 atggaaacat taatgattat tgtaattgtc ggtctaaaaa atgacatcat agttgtagct
    24181 tttctactat ttttaaaaag ttcatcattt aactcttcaa agctttggtt ctcataatcg
    24241 tatctacaaa atagtttaac tacttttatt ccacttaaaa actgtcttaa ttttgaattt
    24301 actttatctg tactttcttg tacattttta aataatctat accctatctt catattaagc
    24361 aatattataa taaatataat taaaactgca attagaataa ttattgacat ctttaaattt
    24421 aattttatag ctataattaa acttcctata cacattattg gtgactttat aaaaactctc
    24481 atcattccat taacgaattg ttgcatttga ttgatatcat tagtaattct tgttattaat
    24541 gaagctctac caaatttatc tatttgtttt aatgagtatg tatttatctt ttcaaataca
    24601 tcctgtctta aatcataaga aaaatgctga gaaactcttg ccgagattac acttcttatt
    24661 attgcaaata ttgcacctaa aaaagttata cctatcatta tagctcctgt tgatagtatg
    24721 tagtctaagt tcttatttga aacccctata tctattattt ttgccattat agttggttga
    24781 gctaaatcac aaaaagcttc caatgttaaa aaaaatactg ctgttagaaa taatactata
    24841 tattttttta tgtatttttt aaaatacctc attcaatcat cccttcatag aattttctca
    24901 ttaccaaaag tatatcataa tggctaattt aattgattat atc
//
LOCUS       DAEHWO010000053        24890 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEHWO010000053 DAEHWO010000000
VERSION     DAEHWO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24890
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.053"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            1..549
                     /locus_tag="KNP54_002594"
                     /pseudo
     CDS             1..549
                     /locus_tag="KNP54_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899647.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            936..1229
                     /locus_tag="KNP54_002595"
     CDS             936..1229
                     /locus_tag="KNP54_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893471.1"
                     /translation="MERGNRIICDQTGKILLQTGEATGDILEHDEITELHFVDIPYGS
                     IDYTRNRIIGINIETKEPILEEIPTFISDEEKRIQELENQILLNENEKVGGIL"
     gene            1229..1411
                     /locus_tag="KNP54_002596"
     CDS             1229..1411
                     /locus_tag="KNP54_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893472.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNRVFELDDVTNTEYRMAVEN
                     YIIEHSEVVEGAELTK"
     gene            1452..1682
                     /locus_tag="KNP54_002597"
     CDS             1452..1682
                     /locus_tag="KNP54_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBF0893473.1"
                     /translation="MNEELVKEKISTLETRVKEHGKQIDRIEIEQAKFAIQIQNLCSD
                     IKNLTGVLKWLVGVIITTLVGFFIFAIQKGIF"
     gene            1702..1959
                     /locus_tag="KNP54_002598"
     CDS             1702..1959
                     /locus_tag="KNP54_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBF0893474.1"
                     /translation="MDNLISFIPEQLLLLVVALNVLGFGFKKYKQLDNKYIPIILLVI
                     GIGFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKDGDK"
     gene            1959..2765
                     /locus_tag="KNP54_002599"
     CDS             1959..2765
                     /locus_tag="KNP54_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0893475.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     IVYTGKVDKSNNYLAEQCKIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVY
                     AERVNDKLATVFENRGAKSDVRGLYWLKHTKAPAILIEVCFVDSKADTDYYIKNKNTV
                     AKLIAEGILNKNINNKENGEGKIMYKHTIVYDGEVDKIPATVVGWGYNDGKILICDIK
                     DYVPGQTQNLYVVGGGACEKISSMTKENYTMIKGNDRFDTLHKVLDFIDR"
     gene            complement(2811..3023)
                     /locus_tag="KNP54_002600"
     CDS             complement(2811..3023)
                     /locus_tag="KNP54_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893476.1"
                     /translation="MTWKNEIKSILVKENISMNELNNLMNEHNNKNNTVENLRQKINN
                     ETMKYSEILTIANLIGYEVVWKKKEK"
     gene            3202..4035
                     /locus_tag="KNP54_002601"
     CDS             3202..4035
                     /locus_tag="KNP54_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893477.1"
                     /translation="MKILFKEAHKMAREIKRKYSNVDYKVQFSLCLSFLNKKGDIKLK
                     ELKGSEKQIIWANDIRTDILNLTNELEKSKIERIKNEDYKIKDMSIEEMTERCKRKFE
                     RIREAISNIENAKFFIDNFRNVLKYNSLNQKAFHINQILKDSQFAKENRNWSFLQGET
                     QASYRLKKVKDYSISYEEAKKIAKEINFNDNWSNEIKENVLEIVEIFDDAVKQATSTE
                     YIEKAKKYIIETLIQKNAQFYRNGFADIKKKQIENYRKIESDERKIEIAYQVFRDGVE
                     C"
     gene            4112..4615
                     /locus_tag="KNP54_002602"
     CDS             4112..4615
                     /locus_tag="KNP54_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893478.1"
                     /translation="MNIDFSTILDLKVNKENVKMIEKEINKINNDIFDISLKDCANGH
                     IGSVKETVGKSLNIETWGHGEINSKIGIRLRFNFYYSKGDKVDIENIENILIYVNSLC
                     SKNVESDLIANVRPKFYKLEEKYSTRIEKCEIRHEFIGINKQEIKEFLEYLTEIEKSE
                     RTVIYKK"
     gene            4647..5117
                     /locus_tag="KNP54_002603"
     CDS             4647..5117
                     /locus_tag="KNP54_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893479.1"
                     /translation="MDKKEAKKFLKVIDMNIDKIEEEAIKAFKESCLIKETNDIKIYI
                     DIQGKVEAIAIQAYAKLLDDDKEINIFTSRQTGNNLDDMFGEIYYVNDYEEFENWCEN
                     KCESLNWDSYKKFNKENFEEIAERNIDDSTSVFLEELREGIESCKQELQNIVEN"
     gene            complement(5426..5731)
                     /locus_tag="KNP54_002604"
     CDS             complement(5426..5731)
                     /locus_tag="KNP54_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893480.1"
                     /translation="MNVEQSKSKKVYLNIGEELSKKMTKSELNKFSQELANYLQYAGL
                     DKNMKIKLFQTILEMVARKKITLSSDSEFTEGILQSDEAEMTTNVGFIIEGLSYHND"
     gene            complement(5941..6141)
                     /locus_tag="KNP54_002605"
     CDS             complement(5941..6141)
                     /locus_tag="KNP54_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893481.1"
                     /translation="MCFKTYVLKRVVNNNQLEITRSFDLDNLICTATEILKDNEIDLI
                     IIDEKNNVVWKNEKSTPQQENA"
     gene            complement(6274..6423)
                     /locus_tag="KNP54_002606"
     CDS             complement(6274..6423)
                     /locus_tag="KNP54_002606"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893482.1"
                     /translation="MFKNKMDKCTHVLTAYISSSYDYYNFLDTQLDDFILEYGENVVS
                     LVYTK"
     regulatory      complement(6477..6574)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            6783..7172
                     /locus_tag="KNP54_002607"
     CDS             6783..7172
                     /locus_tag="KNP54_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0893483.1"
                     /translation="MKQQEVVNKLRRGELMLMEYLWRKNSILSKKEIIEAMKEKYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFQFSYEVLVTKKEYLNAIKEDRKVTKYDSFFIRMF
                     TTMHKKEKMTEEQIKKYIENMEKIGKE"
     gene            7266..7649
                     /locus_tag="KNP54_002608"
     CDS             7266..7649
                     /locus_tag="KNP54_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0893484.1"
                     /translation="MGFKKLPDSELKVMKFIWGLDGNKVASGEVVEAMKQIYDWNKNT
                     TLTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTAL
                     NDEENLSDDKLDMLEEWVKNWEEDE"
     gene            8328..9758
                     /locus_tag="KNP54_002609"
     CDS             8328..9758
                     /locus_tag="KNP54_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBF0893485.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFLLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVSIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKSDGMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(9906..10256)
                     /locus_tag="KNP54_002610"
                     /pseudo
     CDS             complement(9906..10256)
                     /locus_tag="KNP54_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            10251..10772
                     /locus_tag="KNP54_002611"
     CDS             10251..10772
                     /locus_tag="KNP54_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBF0893486.1"
                     /translation="MFSIGGGYAIIPLIQEKVVNQTGWISEKIFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIMSGILGIFFYL"
     gene            complement(10901..11137)
                     /locus_tag="KNP54_002612"
     CDS             complement(10901..11137)
                     /locus_tag="KNP54_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893487.1"
                     /translation="MLECFIAKDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSKKFCQEAYDWFVENQ"
     gene            complement(11447..14875)
                     /gene="uvrA"
                     /locus_tag="KNP54_002613"
     CDS             complement(11447..14875)
                     /gene="uvrA"
                     /locus_tag="KNP54_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBF0893488.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEALNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNHLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQAPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMSDQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            15194..17428
                     /locus_tag="KNP54_002614"
     CDS             15194..17428
                     /locus_tag="KNP54_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0893489.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            17684..19714
                     /locus_tag="KNP54_002615"
     CDS             17684..19714
                     /locus_tag="KNP54_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0893490.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            19711..20163
                     /locus_tag="KNP54_002616"
     CDS             19711..20163
                     /locus_tag="KNP54_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0893491.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            20165..21220
                     /locus_tag="KNP54_002617"
     CDS             20165..21220
                     /locus_tag="KNP54_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBF0893492.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            21287..21595
                     /locus_tag="KNP54_002618"
     CDS             21287..21595
                     /locus_tag="KNP54_002618"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBF0893493.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            21699..22964
                     /locus_tag="KNP54_002619"
     CDS             21699..22964
                     /locus_tag="KNP54_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBF0893494.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            23052..23768
                     /locus_tag="KNP54_002620"
     CDS             23052..23768
                     /locus_tag="KNP54_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBF0893495.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHELEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(23963..24256)
                     /locus_tag="KNP54_002621"
     CDS             complement(23963..24256)
                     /locus_tag="KNP54_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBF0893496.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(24262..24477)
                     /locus_tag="KNP54_002622"
     CDS             complement(24262..24477)
                     /locus_tag="KNP54_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893497.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
BASE COUNT         9558 a         2825 c         3985 g         8522 t
ORIGIN      
        1 aaaataacat tactacaagc attaccattt ttaacagtat cttcttataa ttccattaca
       61 gctacattta aagctgacca cacagaccct acattgctta caaaaataga atattttata
      121 gatgatgtgt taaaagaaac tataacaaca gatttaacaa cagagaaaac aattaactat
      181 acactagaag ataatgcact acacacactt aagatagttg ttacagacag taataatgct
      241 acagcagaaa aagtgttaag tataagtaag aatataatgc cattgcccga agatgtgaat
      301 ctgcaagaca tatcttctaa actaattgaa gttaatgcag gatttaaaac tggaaaaaca
      361 agtattataa acactttagc attaaaaaat atagaagcaa atttaaataa tacattagtt
      421 gaattatcag agaaaataaa aacaggtttt gatagttcag atgctactgc tgaacaactt
      481 caaaatcaga ttactaattt aaataatcag ttaagccaac gtaaaagatg ggctaagggt
      541 acttacactt ttactcaaag tgattatgaa aatttttatt caaggtattc aagtgctgaa
      601 aattatgcta agagtcttac tgttcctatt aatttaaatt tcatccctag tcttgtcatt
      661 gttgaaaaac tttgttttta tggaaatggg tatactgtta atttttatgc tattaataat
      721 ttaaatcaac ttgcttctgt tggtcgtgtt cctaagagta gtggagaata tcgtttttgt
      781 gcttttatgt ttgtaaaaac tattactagc aaagaatttt ctttatatac ttatcgagat
      841 gaatacactg atagtagtag cgtagtatac cgttgtaaag tcggagaaag ttttacatgg
      901 tatgcttatg aataatatga aaggtggtaa tttaaatgga aagaggaaat agaattatat
      961 gtgaccaaac cgggaaaata ttactccaaa ctggagaagc aacaggggat atattagaac
     1021 atgatgaaat aacggaatta cattttgttg atattccgta tggaagtata gactatacaa
     1081 gaaatagaat tataggtata aatatagaaa caaaagaacc aattttagag gaaataccaa
     1141 catttatttc agatgaagaa aagagaatac aagagttaga aaatcaaatt ttattaaatg
     1201 aaaatgagaa agtaggagga attttataat gaatataaat aatgttgtag taagaatatt
     1261 agcagagaga atattaaata agggattaaa tcctctaaaa aatagagtat ttgaacttga
     1321 tgatgttact aacacagagt acaggatggc agttgaaaac tacattatag aacatagtga
     1381 ggtagtagaa ggagcagaac ttacaaaata ggtaatgttc tttttttaat acaaagcaat
     1441 aggaggtttt catgaatgaa gaacttgtga aagaaaaaat aagtacactt gaaacaagag
     1501 taaaagaaca cggcaaacaa attgatagaa tcgagattga gcaagcaaag tttgctatac
     1561 aaatacaaaa cctatgtagt gatataaaaa atctgacagg agtactcaag tggcttgtag
     1621 gagttataat tacaacttta gtagggttct ttatatttgc catacagaaa ggaatatttt
     1681 aattaattag gaggttaaga tatggataat ttaataagtt ttataccaga gcaactgctt
     1741 ttattagtag ttgctcttaa tgtattagga tttggattta agaaatacaa acagttagat
     1801 aataaataca ttccaatcat attgcttgtg ataggaattg gattttcaat atggatgtta
     1861 ggatttaatc cttcatcaat tttacaagga attttatgtt ggggagttgc aataggggca
     1921 aatcaagttt acaaacagtt gaaggatggt gataaataat gaaaatagca atagtaccag
     1981 gacacacttt aagtggaaaa ggaacaggag caactggcta tatagacgaa ggaaaagaaa
     2041 atagaatttt aactgattta attgttaaat ggttgaaaca aggtggagct attgtgtata
     2101 ctggaaaagt agataaatct aataactact tagcagaaca atgtaaaatt gcaaataggc
     2161 aaaatgtaga cttagcagta caaatccatt tcaacgcaaa taaaacaact ctaaatccta
     2221 tgggtacaga gacaatatac aaaactaaca atggtaaggt atatgccgaa agagttaatg
     2281 ataaattagc aacagtattc gaaaatagag gtgcaaaatc agatgtaaga ggtctttact
     2341 ggcttaagca tacaaaagct ccagcgatat tgattgaggt gtgcttcgta gatagtaaag
     2401 cagatacaga ttattatatt aaaaataaaa atacagttgc aaaacttata gcagagggta
     2461 tattaaataa aaatataaat aacaaagaga atggtgaggg aaaaatcatg tacaaacata
     2521 caatcgttta tgatggagaa gttgacaaaa tacctgcaac tgtagttggc tggggctata
     2581 atgatgggaa aatactgata tgtgatataa aagattatgt acctggccag acacaaaatc
     2641 tttatgttgt tggtggtgga gcatgtgaaa agataagttc tatgactaaa gaaaattata
     2701 ctatgataaa aggtaatgat agatttgata cacttcacaa agtattagat tttattgata
     2761 gatagattag aaggtagcaa ctagttagtt gttaccttct ttttttatgt ctacttttct
     2821 ttctttttcc aaacaacttc atatcctatc aaattagcaa tagtcaagat ttcactatac
     2881 ttcatagtct cattatttat tttttgtctt aaattttcaa ctgtattatt cttattatta
     2941 tgttcattca ttaaattatt taactcattc atgctgatat tttcttttac aagaatactt
     3001 ttaatttcat tcttccatgt cattttttcg cacctctctt atttatataa taacataaaa
     3061 aaattaaaag taaaagaata atctacgcta atcaaagtta tatttttgga aatcaaagaa
     3121 aaaactttga aaaagtgttg acttagatat tcatatagat tataatataa ttaacaaata
     3181 aaacaagggg gtaagcaaag aatgaaaatt ttatttaaag aagcgcataa aatggcaaga
     3241 gaaataaaaa gaaaatatag taatgtagat tataaagtac aatttagtct ttgcttatca
     3301 ttcttaaata aaaaggggga tataaaattg aaagaattaa aagggtcaga aaaacaaatt
     3361 atttgggcta atgatataag aacagacatt ttaaatttaa ctaacgaact agaaaaaagt
     3421 aaaatagaaa gaataaaaaa tgaagactac aaaattaaag acatgagtat agaagaaatg
     3481 acagaaagat gtaaaagaaa atttgaaaga ataagagaag caataagcaa tatagagaat
     3541 gctaagttct ttatagataa ttttagaaat gttttaaagt ataattcttt aaatcaaaaa
     3601 gcatttcata taaatcagat attaaaagat tctcaatttg caaaagagaa cagaaattgg
     3661 agttttttac aaggggagac acaagcatct tatagactta aaaaagttaa agattatagt
     3721 ataagctatg aagaagctaa gaaaatagct aaagaaataa attttaatga taattggtct
     3781 aatgaaataa aagaaaatgt acttgaaata gttgaaatat ttgacgacgc agtaaaacaa
     3841 gctactagca cagaatatat agagaaagct aaaaaataca taatagaaac attaatacaa
     3901 aaaaatgcac aattttatag aaatggattt gcagacatta aaaagaagca gattgaaaac
     3961 tatagaaaaa tagaaagtga tgaaagaaaa atagaaattg cataccaagt attcagagat
     4021 ggcgtagagt gttaaaagtt tcaacttgat acaaatatag ttcaccattg aatgctataa
     4081 ttaaaataaa aaataattgg aggtttaaaa catgaatata gattttagta caatattaga
     4141 tttaaaagtt aataaagaga atgttaaaat gatagaaaaa gagattaata aaatcaacaa
     4201 tgatatattt gatataagtc ttaaagattg tgcgaacggt cacattggaa gcgttaaaga
     4261 aacagttgga aaaagtttaa acattgaaac gtggggtcat ggtgaaatta acagtaaaat
     4321 aggaataaga ttgagattta atttttatta ttcaaaaggc gacaaagtag acatagaaaa
     4381 tatagaaaac attttaatat atgtaaatag cttgtgtagc aaaaatgtag aaagtgacct
     4441 tatagccaat gtaagaccta aattttataa attagaagag aaatattcta cacgtattga
     4501 aaaatgtgaa attagacacg aatttatagg cataaacaag caagaaatta aagaattttt
     4561 agagtatctt acagaaattg aaaagagcga aagaactgtt atatataaaa aataactaaa
     4621 aaatggagga aattaaaatg gataaaatgg ataaaaaaga agctaaaaaa tttttaaagg
     4681 ttatagatat gaatatagat aaaatagagg aagaagctat aaaagctttt aaagaaagtt
     4741 gtttaatcaa agagactaat gatataaaaa tttatatcga tatacaagga aaagttgaag
     4801 cgatagcaat ccaggcttat gctaaacttt tagatgatga taaagaaatt aatattttca
     4861 catcaagaca aacaggaaat aacttagacg atatgtttgg agaaatttac tacgtaaatg
     4921 attacgaaga atttgaaaat tggtgcgaaa ataaatgcga aagtttgaat tgggatagtt
     4981 ataaaaaatt caataaagaa aattttgaag aaattgctga aagaaatata gacgatagca
     5041 catcagtttt tttagaagaa ttacgagaag gcattgaaag ttgtaaacaa gaattacaaa
     5101 atatagttga aaattaagta gaagagtatt attattaatg tatatagtat cgcttttaag
     5161 attaactacg agggatttaa aatatttttt aatttattta gaaataatat tgtaataaga
     5221 atttttatat taactacaag ggatttaaat gtcaatttaa tttatagaga aatgatataa
     5281 tggtattttt tagattaact ataagggatt taaatatcaa tttaatctat attcacatga
     5341 tataatatca cattatttta tattaactat gcggaaataa aagcagtgta tttaataaat
     5401 acactgcttt tttaatgcta aagatttagt cattatgata acttaatcct tcgattataa
     5461 atcctacatt cgtcgtcatt tctgcttcat cactttgtaa tattccttct gtaaattcgc
     5521 tatcgcttga taatgttatt tttttccttg ccaccatttc caaaattgtt tgaaatagtt
     5581 taattttcat attcttatca agtccagcgt attgcaaata gtttgctagc tcctgcgaaa
     5641 acttatttaa ttcagattta gtcatttttt tagataattc ttctccaata tttagataaa
     5701 cttttttaga tttagattgt tcaacattca tttttttcaa cccctttttt aagttataat
     5761 tcaattatat tttaaaaatg ctaatacttc aaatataaat atttttgttt aagtatataa
     5821 aacatcaata acattactca acacacctta aaattgattt aaatagctct tttttatgaa
     5881 caaaattaat gatataataa aaaatagaag tgtattggta gtacacttct atagttataa
     5941 ctaagcattc tcttgctggg gagtgctttt ttcatttttc caaacaacat tatttttttc
     6001 atcaataatt attaaatcaa tctcattatc ttttaaaatc tctgttgcag tacaaatgag
     6061 attatctaag tcgaaactac gagttatctc tagttgattg ttatttacaa ctcttttaag
     6121 tacataagtc ttaaagcaca tttatattat tatcctttct cacaaaaata ctttaattaa
     6181 ttttttaaca tagtaatatt taaaagtaga taaaactaaa aagggttctc tagaaatcaa
     6241 tgtctatcta attatactta cttaccaata ccatcacttg gtgtaaacaa gactcactac
     6301 attttctccg tactctaata taaaatcatc taactgtgta tctaaaaaat tataataatc
     6361 atacgaactg ctaatataag cagtcaatac atgtgtacat ttatccattt tatttttaaa
     6421 catataaatt attatacccc taaaaaactt tcataaaaac aaaagaacaa tatctctttg
     6481 gcaactggct gacataactc ataagatatt tatataagtc ttagtcccta tagctttgcg
     6541 tcactaaatt tctctagttt tgccgattta gttttattct acaactaaaa taatacaata
     6601 gaattagtta ttattcaaca aaattatttg aaaatttaat aattttatag atatgaaagt
     6661 tattttcttc taagaaaaca gactaaatgc gtagaatatt tggtaaaact tacctgtata
     6721 aattgaaatc agaaggtttt attattgatt tagattagaa caatttgagg gagtgacata
     6781 aaatgaaaca acaagaagta gttaataaac tacgcagggg agaattgatg ttgatggaat
     6841 acttgtggag gaaaaattct attttatcta aaaaagaaat aatagaagca atgaaagaaa
     6901 aatataagtg gaggaaaagt actacagaaa ttctattaaa aagattagta aaaatgaaaa
     6961 cattaaaaaa gaagaggata ggttttcagt ttagttatga agtgctagta actaaaaaag
     7021 aatatttaaa tgcaataaaa gaagatagaa aggtaactaa atatgatagt ttttttatac
     7081 gaatgtttac cactatgcat aaaaaagaaa agatgacaga agaacaaata aaaaaatata
     7141 tagaaaatat ggaaaaaatt ggaaaagaat aatttatata tatattaatt atttttaaaa
     7201 taaatttgtt ataatattta aatatacata aacatacata aatttacaaa aagggggtgt
     7261 agcttatggg attcaagaaa ttgccagatt ctgagttaaa agtaatgaag tttatttggg
     7321 gattagatgg aaataaggta gcatcaggag aagttgtgga agcaatgaaa caaatttatg
     7381 actggaataa aaatacgaca ttaacaatat tgtctaagct tgcaaagaaa aactatttgt
     7441 attctcaaaa aacaagcaag tgtacatatt atactatcgc tgtaagagaa aaagattatt
     7501 taaaagttga aacaaaaaaa ttctttagtt tttttcataa taattcttta aaaagttttt
     7561 tcactgcttt aaatgatgaa gaaaatttaa gtgatgataa attagatatg ttagaggaat
     7621 gggtgaaaaa ttgggaagaa gatgaataaa atgaatgtga tactaaaatg atactaatat
     7681 gttttatagc gtgttaaaaa atatagaaaa tatagaaata atagaagaaa attaatgtaa
     7741 tagataaggt tttatcagat taaaaagaaa atcaatagaa tgggaataaa atatagaatg
     7801 ccaaaaatcc acataaatac aggatttaag gtctctctta cttctatgtt atactggttt
     7861 gatactatca atatttgcca gtatcttatg gattaataag taaaaaacat cctgctgaat
     7921 gataaattca gcggggtgtt tttattttgt tttagaactc ctttgctctg aaactcgaag
     7981 tatttaacac tgatgatttt gttatctttt agttcctttt gtgtcatgct ctgaaagaca
     8041 aattgataca ataaaaaagt aatttcttaa tcattgatgg agatatgtat ttatgttact
     8101 cttgatggta atttgagtaa tattgttcat agctttttat attcaattaa ttagaaaacc
     8161 atttggtata atcataaata aacttgatga tataatagaa aagatttata attattagaa
     8221 gtatataaaa gtattttatg tctatgaaat gtatgtctat aaaacatata gatgactttt
     8281 gtatattaat gtatgaatat tgatattata gaagaattga gttgtcaatg atactaaatc
     8341 aaatatttat agaagctgga gggattatga gaaataaaat aattatagga attacttttt
     8401 tacttgtatt actaatgtct ggatgtgctt caaaacaaac cgcagaaata aacgtattag
     8461 caactactga tttacatgga gttatacctt atgagttaac ttcttatgta aaagaagaaa
     8521 gaaaaaaaga taaaaatcta actttagtag atgcaggaga tttttttgat agtggagaag
     8581 tgtttggttc tagcatggat agttatttta gtgctagata taaagatggt gataataaca
     8641 ctgaaagtta tattgagacg cctatttcaa aagatatgaa agaggtaggt tatgatgttg
     8701 cagttcttgg gaatcatgaa tttatatcca acaataaatt ttatctagat aatatgatat
     8761 ctgattttga gaagcaaaaa ataaatattt tatcggcaaa tacgtataaa aaaaatggag
     8821 acagttatac aaaaccatac ataataaaaa atattaatac acctgaagga aacgtaaaac
     8881 taggaatttt agggcttact ataaaagaag ttggtgagag gaaacagtgg aaagatggaa
     8941 aacttgttga ctctaagtct ttagaactaa aagaccaaga gggctacaat ggtgaattgt
     9001 atatgaatga tttagtagaa gatgctaaaa agtgggttag tataatggaa aaagagaagc
     9061 ctgacattat agttgctgtg gcacatacag gtgagaaacc taagaaacct aaaaacccag
     9121 gaaatagaat acaagactta gctcaacaag ttgatggaat tgatgctata gttgcaggtc
     9181 ataatcatgt tcaaattgag caacatgatt ataaaaataa atcaggagaa aatgttatag
     9241 ttactgagcc aggaaagcat ggggaatgta tttctaagat taattttaaa ttagaaaaaa
     9301 acaatgataa atggaatata gttgacaaat ctagtaaatt aattaaattt gaaaaaaatc
     9361 aagaaagtga taaatttgga gaatttattt cttcaattaa taaagtaagt aaagataaga
     9421 aagaaataag attatcagaa gtaaagactc ctgaatggga taaaatatat gtttttaaat
     9481 ctggaacatc tgcagatgat atatataaaa caataggata taaatggaga aatatatcat
     9541 ctccaaagag tgatggcatg gtgcagattg ttgtaatgaa taataataag cctgttagct
     9601 atatatatgg tgaagctgaa gttatgccaa ttaatataaa atgtgatgaa tcagagtata
     9661 aagataatgt tgtaactatt tatcctaata aaaatgataa atttaaaatt gaaaaaggta
     9721 aacaagaata tagtattaat ttaaaacata tacaatagaa acttttatct tatttaagtt
     9781 tagattgtac ttaaaataaa gtgtgtatta ttttaaaaat tgatgataat taaaatcaca
     9841 acattaagga atagtacaca ctttttatgc taaaaaatag aatgttaaaa aattaaacct
     9901 ttaaattaaa gtacattgct tatattatcc aatattatct tcaaaggttg tgtaatattt
     9961 ttatccttat gtaatattgc taacatttta ttttccatat ctatcccatc taattcaatc
    10021 aatcgcaatt ttttatgtaa gagtgaatct aataataaat tttctggcaa aatggttata
    10081 cctaaccctg cttgtgcagc tttaataagt gcaaaagaat taacactttc ccaaacagga
    10141 taagcttttt ggtttgaaag agataataca ctgtccaaag tatcgcgaat ggcacttcct
    10201 tgctcacgta acaataacgg aaacgtgcat aactgtcgta gagataaggc ttgtttagta
    10261 ttggtggtgg ttatgcaatc atacctttaa tccaagagaa agtagtaaat caaactggat
    10321 ggataagtga gaaaatattt acagatatta taactatttc acaaatgaca ccagggccac
    10381 tggctgttaa tacttctact tttgttggac ttcaaattgg agggttttgg ggagcagttg
    10441 cagccacttt aggttgtgta ttatgtggtg tagtaatatc tctattttta tataattttt
    10501 ttcaaaagca tcagaactct acttatatat ttgaaatatt aaatggtcta aaatcagctt
    10561 cattaggttt aattatctca gctgcggcta caattataat tcttgcatta tttgggacga
    10621 ataaagtgta cttcaattct atatttgaga tgctaaactg gactgcacta ataatctttt
    10681 ttgttacact actgatagta cgtaagtgga aaattaatcc tattgtgatt ataataatga
    10741 gtggtatact gggaatattt ttttatttat aagtttttgc taagtaaagg atatctattt
    10801 ttttatatct taaatccaaa tagccaataa agtaaggcta tttggatttt taataaattc
    10861 tgaaaagata atcagaaacc tatataacat ttaaattata tcactggttt tctacaaacc
    10921 aatcataagc ttcttggcaa aatttcttac tatctatata gtaactatta tgaacattat
    10981 taatttcaac aagtttcttt ttacatttta gtgaattata atagctatca aaatattggg
    11041 ttttaaaata tctatcatga agtgttttaa agacaagagt aggtatgttg actccatctt
    11101 ttatcttact atcttttgca ataaagcatt ctaacattgt attaattatc tttgtactat
    11161 ttttccaaat atgaggattt ttcttttcaa atattttata aaattcatta tcatagactt
    11221 cattataacc tttatattta ggtggtttta ctgttatgtg aaaattagga agaaacttaa
    11281 agaaaaaata taataatttt tatgttctgt tttatatatt attcatattt tatcacagat
    11341 aatatactaa agttaatttt tttattgtac aactattata ataattcttc tataatataa
    11401 gacattctat aattttatat ttaagttcat gtgtatttaa ttgtttttat ataaaatgtc
    11461 cagtaatact atttggattt atttttattt catcaggagt tccagaagca acaatttccc
    11521 ctccatttat tccactgtct ggacctatat cgataatcca atcagaagca cgtataacct
    11581 ctgtattgtg ttcaataatt aaaagtgaat gctgttcatt tacaagtttt ctaaaagtaa
    11641 ttaacaaatt ttctatatct ttaaaatgaa gtccagtagt aggctcatcc aatatgtaca
    11701 gcattcgttt tttagttttt gtccctaatt cttttgctaa ttttatcctt tgagattctc
    11761 ctccacttaa tcctaatgta ttttgtccaa gctttagata tccaagtccc acttcatcta
    11821 ataaggagag ttttctatat atatcagagc aatcgctaaa aaatgttttt gcttctgcta
    11881 cttccatgtc aagtatatct gcaattgtct ttcccttgta ttgtatagac agtatttctt
    11941 tttgatatct cttaccttga cattcactac aagttaccca ttggtctgac atatattgca
    12001 gaataatttt tgttttacct aatccttgac agtttgggca ttgccccttt ttgctattaa
    12061 agctaaaata gctttcatcc aataattttt gttttgcttg tggagtttca gcaaatagag
    12121 aacgaatttc atcaaaaata ttgatatatg tagcaggtgt agaacggcta gattttccaa
    12181 taggtgcttg gtccattaag ataaaatcat caatagcatc aaatccagta aattcagtat
    12241 aatttttatc tgggatagat ttttgtttca atttttcttc tagagcagga agtaaactgt
    12301 gaaatacaag agagctctta ccagaaccac taacacctgt aatagagcac atacagttta
    12361 agggaatttc tacatcaata ttttttaagt tatttgcatg gcatcctttt aagcttaacc
    12421 atttacttgg tataatttta ttttgtgaac ttattttatt gtatgtactt aaatatttac
    12481 ctgttataga gtttggattt tttataattt cttgggttgt accttctgcg ataatgaacc
    12541 ccccttttgt accagcactt gggcctacat caataatata atcagcagac agtattgtat
    12601 ctttatcgtg ttccacaact ataacagtat tacccttatc tcttagctct tctatcattt
    12661 tgatgattaa attatggtct cttgggtgta aaccaataga tggttcatct aaaatgtagg
    12721 ttaagcctac taattcactt cctagctgac ttgataatcg tactctctgc agttctcctc
    12781 cagataaagt tggagctgtt ctatctgttg atatatagct aagacctacc tttaatagat
    12841 aactaactcg aatttttaat tctgttaaga tatcatttac caaagagagc tcattttttt
    12901 gaaggtgatt tggtaattca cacaaccaat tccataactg ttctatcgtc atttttgtta
    12961 gttcagggaa gcgataacct ttgattgtag tgaatctagc ctcaatgcac agcaattcgc
    13021 caccacatgt attgcaagga attttgttca tatattgatg caaggtatta ttttcagaac
    13081 tagattctct aaaaagtctt tgaatgtggt tgattgctcc tgaagcaggt cttctaatct
    13141 ttgattctcg tccctttgat tcaaagctaa attcatatat cttatcgtct gtaccatata
    13201 agattgcatc tataaaatct cttggtaatt cattccaagg tatatctagg tctatatttt
    13261 tatcttttgc tattgcatat aattcaccta ccatccaatt accatttggc tttttccccc
    13321 tcaattttcc aaaatagtaa gtagctccat ctaatattga aatagttggg tcttttacaa
    13381 ttaattgagg attaacttga taggtaaaac ctaatccatt acaatcgtga caagctccag
    13441 tatgggagtt agcattgaag gttgaagtat ttatcttaga aaaaatagtt tgacaatgtg
    13501 gacaataatt ttttgtatta ttcttttttt ctaatggaat tttgcaatat ggacagtaac
    13561 tttttccgat tgatacaaat aacattctta aataatccca aatgcttgta agagtaccaa
    13621 cagtagagcg aggattttgg cttccttttt tctgttcgat ggctatagta ggggttaatc
    13681 cctgaagtaa atcaaattcc ggtttttgaa gctgttctga aagttttgct ccgttactta
    13741 gattttcaaa ataacgtctt tttccttctt cataaatcgt atcgaaagct aaagaagatt
    13801 ttccactacc acttacacct gtaataacag ttatttgatt ttttggaatt gtaacttcaa
    13861 catcctttaa attgttttgc cttcctcctt ttaaatagat agagctttta ttatgacaaa
    13921 gtgaattttt aattgattta tttattgctt ttgtaaattt gaatttcttt tctagttcaa
    13981 gaggattgcc taattctttt atttccgaaa tacctaatat ttttaactga gaaaagattg
    14041 atttcaaata atcttcaggc aatttttcta ttaacaaatt aagggcttct atttttatat
    14101 ttccgcttga taatatctct gccatttcat ctaataaatt tttttctgct cttgttaatt
    14161 gattgtattt tttggaactt aattctgtcc ataaatccca tggaagcaat tctaaaccaa
    14221 tcatattatt aaagtcatgt agaagattac cctttacaga atgccaacct ttccaatttt
    14281 tattatatcc aaagtcatct ggatgagcat gtccttgccg acatcttatc caggcttctg
    14341 aaccagttaa aaaaccatct gtttttccga catcatgagt gtcaaaatta atttgaaaat
    14401 aatttttttg tatgtcatct atttgtgcat ctattcttat ccatctcttt gttagagtat
    14461 catagtattc tacaagccag tggtcttcat aagtaagctc actttcaaaa taattagcaa
    14521 aacctgctct cattctagcc tcaaaacctc gatatcttag gagcgataca agaagtaaag
    14581 aataatctct gcacattcca acaagccttt gttttgggtt tcttggaata gttagtgggt
    14641 tagaatttat ttcaaatatt ctttttaaca tttgaggaat tgtacgaagc aattcctcat
    14701 cagattgttg cttattaaag gatataccat ataattttcc ttggtctcca tgaattacta
    14761 ggctttgaac cacttttaat aactcaattg gagtctttgg taaatcttga tatttatttt
    14821 caaatttttt aggatttgtg atgatacttt gatttttata gttatttatt ttcatttata
    14881 tttcacctct ctaaatggat gatataccct gacatggtgt catatgcaag gacaatttag
    14941 atttttggcc aaaatttaaa aaataaataa aaaatgatac agtgataaat tgtaatacaa
    15001 atatagtttc aaattgcata taatataatt atttaataaa accattatct attgaatgtt
    15061 aatgaaatgt taagatggca ttcttgaata ttaagaaata gaatactata atatagtgtg
    15121 aaggattttt agtaaaaaaa tttgtaagtg ttaatataca ttaaaaaata ggtttataat
    15181 ttggaggaaa aaaatgaaat tatcaaggta taagaaaaat agtttagttc tgtctataat
    15241 tttatgttca cttattattt caatccttgt aattactgtt tttaataccg taaaactaca
    15301 caatatatct aataaacaat ctaaaaacta tttaaatgat gtatctacac agattgtaat
    15361 gaatgttgat tctaaaatca aatttatttt atccgactta agaataatgg cagattttat
    15421 taagcaatat gaaggtgata gtcgatatga gtatttatct aaaagaaaga ctagttataa
    15481 gtattatgat gttggaataa tagatttaga aggtaaagct gagtttttaa gtggaaaaaa
    15541 gtttgactta aagaatactg tttcctataa aaaaggaatt gaaggtaaag aatactcaga
    15601 agtaatagag tcaatgggtt ttgttcttta tagtgtacct atatttaatg ataatcatga
    15661 agtatctagt attttaatag gtgtatccaa taaagaaagt atgaatgaga ttcttaatat
    15721 agataacttt aatggaaaag gaactattga aattattaat agtaagggaa aacctctttt
    15781 cataggaaaa aatactgaat taataaagga ccttagccat aaatataaga gttctggaga
    15841 tgaaccttgg gcacaaaaga tgcttgagga ttttaaaaat gataaatcag ggaatattac
    15901 aataacctca tcaaaaggtg tacaatgctt attaacttat catccaatta caagaggttt
    15961 aaatgattgg cattttcttc tcatagtacc tgaagatgct gtacttggtg aacttaataa
    16021 attaaactct tttacaataa caatgacatt tataattaca tgtattattg gaattataac
    16081 attaatttta tatattataa gaagaaaata tgtaaatcaa atagaaaata ttgcatattt
    16141 agatagtata acaaatggta taaattcaac taagtttagt atgctagtca aacctttaat
    16201 ttcagaatca cctgatagta cttatatgat gatagcaatg aatataaaag attttaagct
    16261 aataaatgat tgtttcggta gtgaaaaggg aaatatgaca ctaaaacatc tttacaatat
    16321 tttgtataaa aacattgatg aaaatgaaga atttgtgtgc cgtcatgatg cagacctttt
    16381 ctatttgctt attaagaata gaccagtgtt agaagccctg gagttattat ataaaataga
    16441 agctgacaca aattatttta ataaaaatag ggaaaatcca tactttttaa gactatcagt
    16501 aggtatttac acaattgaaa atcataatga agatttaatt acaatacaag accatgcaaa
    16561 tacagcaaga aaaagcttta ataaaactca tcaaagtgat ttttcttttt atagtgatat
    16621 agaaagaaaa cgattaatat ctgaaaagga aatttcaaat ttaatggaaa aagcccttga
    16681 aaataaagaa ttttttatgt gcttacaacc taaaattgat ataaaaagtg gaaaaattag
    16741 tggagcagag tctcttgtgc gttggaaaaa ttcagaaaag ggcataattt atccaagtga
    16801 ttttattcct cttttcgaaa aaagtggatt tatatgtaag ttagatttat atatactaga
    16861 agaaacatgc aaattgattt ctaagtggat aaaagaaggt aaagaagtgt tgagaatttc
    16921 tgttaatgta tcacgtcaac atctgaatga taaattgttt ttagaaaaat ataagcatat
    16981 atgcaataaa tacaatgtac caacatgtct gatagattta gaacttaccg aatctatttt
    17041 cttagaaaat ccagaagcta tagatataat agaggatatt cattctaatg gatttaaatg
    17101 ttctatagac gattttggat ttgggtactc atcattagga atattaaagg attttaaagt
    17161 tgacataatt aagttagacc gttcattctt tgttagcaaa aataatatag accgtggtaa
    17221 ggtagttatt aagtctatta ttgaacttag caaaaggcta ggtatgaaag taactgctga
    17281 aggaattgaa gaattagaac aagttgagtt tctaaaaaat gtgggatgtg attatattca
    17341 aggttatgtt ttttcaaaac cattattaat ttctgatttt gaaaattttg catatgaaaa
    17401 taataaaatt aaaaatatcc attattaaat gtacaagata aaaaatttag gcaagttata
    17461 taattaaaaa tataacttgt cttttttatt tatatattta ataaaaatat atttgcagat
    17521 tttgtaaaaa taattttcaa atgttgtaag ttgtggctaa agctttattg tattattctg
    17581 aatatagaaa gatagttact gtcttagata aaaactgaaa catacataat aatataaaat
    17641 ttgctatatt aataactcta attattttgg aaggagggaa aatatgataa gtgggagaat
    17701 gttactcatc atgaattttc taaaaggaaa aaataagaca agttacaagg atattagcaa
    17761 acaacttagt atagaagaaa gaaaagttag atatgatata aataatttaa atattgtttt
    17821 gcgttcatta aacaagtcag taatacaaaa gatgaacaaa ggtgtgttaa ttattcctga
    17881 tgacttccaa gtagtatgta taaataataa cgaatatgta ttttccttaa ctgagcgagt
    17941 atctattatg aaaattatat caatgtttaa aatagataat ctaaacttag aaaaattaag
    18001 taaagaattt caggtttcta gaagttcaat taaaaatgac cttaatgttt tgtcaagtga
    18061 attagaaaga aaccaaataa ctattactta tgataaatct tttaaaataa gtggagaaga
    18121 agacattata tataagcaaa gattgaacat attaaaatcg tattcttatc tttttggtaa
    18181 ggaaaaatct gatttaagtg tatttgagaa gtatttagtg aatgtaattg aaaaaatatt
    18241 caaagggatt tatttgattg atatatataa ttggtctatg aatttattat tgcaaatggg
    18301 atggacttta aatgatgaat cttttacatg gtatgtgtca aacattttcc tttttacatg
    18361 gtatatacat tcagatgaaa aacatccttt agaatctgct tcattaagtg agccgtgttt
    18421 tgaaaataag tttgaccaag aatttgaaac aattattcaa aaaaagttga ctaaggaaca
    18481 aatttttctg ttaaagagtt ttgtattttt tacaaataaa tatgcaagtt taaacgagga
    18541 tatggatttg attagtacag aaattatagt tcaagatcta atttacaata tgtcagaaat
    18601 attagagatt agctttaaag aagatatgat tctttataaa ggattactca atcatattgc
    18661 cccattgata gagagaatca aacagaatat acagatttat gaggaattac ttcatgtaat
    18721 accagataaa tatcaatatg tacttgaagc tactaaggtt tctattcaaa aaaacagagt
    18781 tttaagtcaa ataaagaatg aaaatgaaac aatacttttg gcaatacatt tcttaggaag
    18841 tatacataga aatgagagga ataactacaa aaatatattg ttagtttgtg gatttggata
    18901 tggtgtaatt gctatgttaa aggatagttt agtaaatgat taccagataa atatagtaga
    18961 gagtattcca tcatataagt tacaagatta taaagaatgg gaaagtattg acttcattat
    19021 aacaacatca aagatagtaa tagacttgcc taaaacaatt attgagataa atccattttt
    19081 acaagaagag gattatttga agtttgaaga aaaagggata aaaagaaaga acgtcttaac
    19141 taattatatg tcaataaaaa aaaggttgga ctttttagaa gaagatgccc aaaaaagagt
    19201 attaagtatt atatgtcaag aacttggata cagtgatgag agaatattat ttagacaact
    19261 taatttaagt gatttaatag gaattgatac cataaggata attgatggag atatgaaatg
    19321 ggaagatgct gtaaaaatta gttcaaacat acttgctaat tgtgattttg tatcagcaca
    19381 atatgctgag aatattatag atattttaaa aaatgtgggt ttttatgctg taaaagataa
    19441 cgaatttgct ttactacatg gcaatgatag ttcattagtc aaagtaagtt cgataagttt
    19501 attaatatgt aaagaagcag ttagttttgg agataaaaag gttaaaatca tattttgcct
    19561 agcaagcaga gataaaaaag agcaaattcc tgcaataatt aatctaacta aaatggttta
    19621 taagactaat tttattgcta tgttagaaag tgcaaagaca aaagaagaag cagaagtttt
    19681 aattcataaa tatgagaagg aggtcactgt atgaataaat tagttaatgt aaaatgttca
    19741 tttaaaatac atgttaattc aaaagaagaa gccattatat cgttagttga tgtagtgtca
    19801 aaagaaggat atttaataga taaaaatcaa tttttaaaag atgttttaaa gagagaagaa
    19861 acattgtcga cttatattgg acatggtata ggtcttcctc atagtcaaag tgtaggtgtt
    19921 aaaaactctt gtattacaat aggaaagctt gatactccta ttgaatggac agaagaagga
    19981 gaaaaagtgg atttaatatt tttgatatca gtaacaaaag acaatgaaaa taatcttcat
    20041 ttaaagattt tatcaaaatt agcacgttta ttgatgcatg aaagttttag aaatcaaatt
    20101 agatgttcag atgaacaaac tgtttataat cttataaaag aaaaaataga ggaggaagat
    20161 taaaatgaga attttaaagt ttttgcaaaa acatcttatg acagcaacat cttatatgat
    20221 tccatttgtg gttgcaggag gaatattatt tgctttatca gtaactttaa gtggacaagc
    20281 tgctgttcct gaaacaggct ggttggctaa actgaatcaa attggagctg ctggcttggc
    20341 tttattcatt cctatattag gtggatatat agcatttagt atggcagata aaccaggatt
    20401 agctccaggt atgataggtg catatttagc aaaagaagta aatgcaggtt ttataggtgg
    20461 tatcatagca ggatttatag caggatttgt tgttttacaa ttaaagaaaa ttaaattagc
    20521 tcctacaatg agaactttag gttctatatt tatttatcct ttagttggta cattgattac
    20581 aggtggtata attgtatttt taattggaga acctatagct tcttttatga catggatgac
    20641 aaactggtta aatggaatgt ctggtgtttc taaaattcct ttaggtggaa tcttaggagg
    20701 aatgatagcc tcagatatgg gtggccctat aaataaggtt gctgctactt ttgcccaaac
    20761 tcaagttgac acacttccat atttaatggg tggagttggc gttgcaattt gtatacctcc
    20821 aattggttta ggattagcta cattattgtt tccaaaaaaa tttagcaagg aagaaagaga
    20881 ttcaggtaaa gcttcactat taatgggatg tgttggaatt acagaaggag ctattccatt
    20941 tgcaacatca gatccagtta gagtaatacc ttgtattatg gctgggtcga ttgtaggaaa
    21001 tattatggct tttttattag gatgtttaaa tcatgcaccc tggggaggtc tgatagtgtt
    21061 acctgtagtt gacaataggt tggggtatat tgcatcagta ttaactggag cagtagttgt
    21121 tgcggtatta atgaaattag taaaaaaaga cgtgaaagaa gatgaagaaa ttgaagaaga
    21181 tttagatgaa tcaattgaat taatatttga agaattataa atataaatgg aaggaatttg
    21241 tataaaaaag taaatataaa actataaatt taaaggagat aagaatatga aaattgtagc
    21301 agtaacatct tgtcctagtg gagtagcaca tacttacatg tcggctgaat cacttgaatt
    21361 atcagccaaa aaatttggta tagaaataaa ggttgagact caaggaagct ctggaataga
    21421 taatgaattg tcacttaaag atattgatga agcaacttgt gtaatattga ctaatgatgt
    21481 tgagattaga aatatggaac gttttaaagg aaagaaggta gtaagaatga gtgtatctga
    21541 gataattaag aaatctgatg cattaattaa gaaaataaaa gatacttttc aataaaaatt
    21601 gatttatttt acatataact caaagatgtt tttaaagaaa tttttattaa aagcatcttt
    21661 gaaaatatct taaaaataga ataaaaggag atatagtcat gaaaaagtta ccaataaaga
    21721 ctgtcgtgca aagattacta aacttacaag aagaggggaa aagtgcaact cttttaggaa
    21781 ttggtcctat gtcaccaaac ttgttacaag caagttttga actagcaaaa gatgatgatt
    21841 ttcctttaat gtttatcgca agtagaaatc aagtagatgc agatgaacta ggtggcggtt
    21901 atgtaaatgg ttggaatcag gaaactttta caaaagatat taagaaggtt gccgacaaag
    21961 ttggatttga tggtttatat tatttatgta gagaccatgg tgggccatgg caaagagata
    22021 aagagagaaa tgaccatttg cctgttgatg aagcaatgga gttaggaaaa aaatcttatt
    22081 tagcggacat tgaagcaggt tttgacctat tgatgattga ccctacaaaa gacccatttg
    22141 aaattggaaa agtaattcca ctagatgtag tactagaaag aactgtagaa ttaattgagt
    22201 attgtgaaaa cgagagaaaa agacttaatc taccagacat aggttatgag gttggtacag
    22261 aggaaaccaa tggaggtctg acttcaactg agacgtatga aacatttata actagactaa
    22321 aggttgaact cgataataga ggtttgccaa tgccaacatt tatagttggt caaactggta
    22381 ctttaactag aaagacagaa caagtaggaa cttttaattt tagaaatgct tatgatttag
    22441 ctcaaatggc taagaaatat ggagttggtt taaaagagca taatggcgat tacttagatg
    22501 atgtaacttt attagaacat ataccatctc aaattattgc tacaaatgta gctcctcaat
    22561 atggtactga agaaactagg gcatatttaa aattagcaga agttgagtgt aaattagaaa
    22621 aagagggctt agttgagaaa acttctaata tcagacatgt tcttcttgtt aatgcaattg
    22681 aatgtggacg ttggagaaaa tgggtagtag gagaacaaaa aaatctaact actgaagaga
    22741 tatttaagga tgaagtttta tctaatgaaa tactagatat tgcaggacat tatacattta
    22801 ataatgatga tgttaaaaaa gaaatagaag tgctttatga taatttaagt aagaataata
    22861 ttgatggtca aagatttgtt gtagaccata ttaaacgtcc tttgcgtgat tatgcagaat
    22921 gctataactt aaaaggtgtt actacgagga ttttaaataa ataataggac ttatagtggt
    22981 gagtattgtt atactaggta tttatagtta taattatact taccactatt aaatttagga
    23041 ggactaatat tttgattaat ttaatttttg atgtagatga tactttatat aatcaattaa
    23101 cgccttttta cactgcatat aataaagtgt tttcttcaat aaaggatatt tctattgaag
    23161 atttatatat gagtagtaga aagtatagtg atgaggtatt tcatatgact gaaaatggag
    23221 aaatgccaat caaagaaatg catatttata ggataatgaa agcttttgag gagttgggaa
    23281 attctattac agaaaaagat gcacaaagtt ttcaagatga gtatatatat caacaatcac
    23341 aaattacact aataccagaa gttgagagga ttttaaattt ttctaaagaa agaaatatta
    23401 atctaggaat tataactaat ggcccatcaa accatcaaag aatgaagtta aagcagttaa
    23461 atattgaaaa ctgggttgat aaaagtaata tttttatttc tagtgaggtt ggattttcta
    23521 agccagatac taatattttt agagtagctg agaatgttat gaatttagat agagaaaata
    23581 catattatgt gggtgattct tatagaaatg atgtattagg tgctaaaaaa gctggttgga
    23641 agagtatatg gttgaaccat aggggacatg agttagaaga gttgttttat aaacctgatt
    23701 ttgtaatttt ggaacataag gatttgatat ctttatttat aaaaatatgt agttataaaa
    23761 atatgtagta aaaaaatgtt aataatagaa ttgtataaaa taattaataa taactatata
    23821 aaattatatg tttagattgt gagcaatcta ttttatgtta aaaatagatt atttagaaga
    23881 aggggaaatc ttaaaaaaat ttgaatatcc cctttttatt atttaattaa aatgaaatag
    23941 ttagaaatat attttattta gtttagtcaa taacattttg ggattcttta taactacatg
    24001 ttaactgttg aataggttta tcatatggtt taacccatcc tttattaata cttaattctg
    24061 taagtgctgt gtgaccttct accatttgag ttaatgaagc tgaatatata gctcttagtt
    24121 caggtgtact acttgtcaat gcagaattaa gatacatatt ggcagatgct ttagcagatg
    24181 aaagcatact taacattatt actttatcgt ctatataagt attgttctta attagatttt
    24241 ctatcatatt tctcatgtta tctatacctc ctcagaaatt agtatttcat tttcaactat
    24301 aaattgttgt atagctttaa ttcttccttc tgttgctaat atactagatt ctgattgtct
    24361 ttttagatct tcatctgata ttaacatatt tattgctctt tgcataagta atccgtcaga
    24421 ctccattttt ataattgctg ctaaagatat tttttcagtt tctgaaagta ttctcattta
    24481 atcatctcct atattgtaat ttatgcttta atagtatgtc tttcttttca aggaaataac
    24541 cattacactt ttttacagta ttttatattc tcgttatatc aaaatttagt cgacttaata
    24601 tattaatata attttgtagg atatttatca ttaaatatct ataaaataaa ttgtttgaat
    24661 attcataaag caaaatttat ttgtatgtac ttcttcaaga gtaaatatga gttttttcaa
    24721 aaaattaatt tttatgataa ttattaaggg ctatattttt cttaaagttg tgattatcat
    24781 tattaattta caataaaatt gccgaaaagc cctctccttt aggtgtaggg atgaaaggta
    24841 aggtcttaat ataaaaaagt tagaataatg cttgtaatct aataccgcta
//
LOCUS       DAEHWO010000054        24632 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEHWO010000054 DAEHWO010000000
VERSION     DAEHWO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.054"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(507..683)
                     /locus_tag="KNP54_002623"
     CDS             complement(507..683)
                     /locus_tag="KNP54_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893498.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1258..2280
                     /locus_tag="KNP54_002624"
     CDS             1258..2280
                     /locus_tag="KNP54_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893499.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDVGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            2294..3181
                     /locus_tag="KNP54_002625"
     CDS             2294..3181
                     /locus_tag="KNP54_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893500.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3187..3960
                     /locus_tag="KNP54_002626"
     CDS             3187..3960
                     /locus_tag="KNP54_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893501.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            4072..4797
                     /locus_tag="KNP54_002627"
     CDS             4072..4797
                     /locus_tag="KNP54_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893502.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            4801..6204
                     /locus_tag="KNP54_002628"
     CDS             4801..6204
                     /locus_tag="KNP54_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0893503.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDDGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            6215..7039
                     /locus_tag="KNP54_002629"
     CDS             6215..7039
                     /locus_tag="KNP54_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBF0893504.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNT
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(7364..7984)
                     /locus_tag="KNP54_002630"
     CDS             complement(7364..7984)
                     /locus_tag="KNP54_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0893505.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            8250..8582
                     /locus_tag="KNP54_002631"
     CDS             8250..8582
                     /locus_tag="KNP54_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0893506.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8702..9343)
                     /gene="pcp"
                     /locus_tag="KNP54_002632"
     CDS             complement(8702..9343)
                     /gene="pcp"
                     /locus_tag="KNP54_002632"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBF0893507.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(9364..10296)
                     /locus_tag="KNP54_002633"
     CDS             complement(9364..10296)
                     /locus_tag="KNP54_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBF0893508.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(10318..10983)
                     /locus_tag="KNP54_002634"
     CDS             complement(10318..10983)
                     /locus_tag="KNP54_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBF0893509.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLRQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(11555..12031)
                     /locus_tag="KNP54_002635"
     CDS             complement(11555..12031)
                     /locus_tag="KNP54_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HBF0893510.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(12034..12438)
                     /locus_tag="KNP54_002636"
     CDS             complement(12034..12438)
                     /locus_tag="KNP54_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBF0893511.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(12413..13042)
                     /locus_tag="KNP54_002637"
     CDS             complement(12413..13042)
                     /locus_tag="KNP54_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0893512.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      13408..13451
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13552..14520
                     /locus_tag="KNP54_002638"
     CDS             13552..14520
                     /locus_tag="KNP54_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBF0893513.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            14522..15085
                     /locus_tag="KNP54_002639"
     CDS             14522..15085
                     /locus_tag="KNP54_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBF0893514.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            15093..15782
                     /locus_tag="KNP54_002640"
     CDS             15093..15782
                     /locus_tag="KNP54_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0893515.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15909..16637
                     /locus_tag="KNP54_002641"
     CDS             15909..16637
                     /locus_tag="KNP54_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBF0893516.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAQDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            16651..17325
                     /locus_tag="KNP54_002642"
     CDS             16651..17325
                     /locus_tag="KNP54_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBF0893517.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            17351..18187
                     /locus_tag="KNP54_002643"
     CDS             17351..18187
                     /locus_tag="KNP54_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893518.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            18203..18874
                     /locus_tag="KNP54_002644"
     CDS             18203..18874
                     /locus_tag="KNP54_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893519.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLINQNIY
                     DLVILDLMLPNINGFDILKKMRINNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18864..20096
                     /locus_tag="KNP54_002645"
     CDS             18864..20096
                     /locus_tag="KNP54_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0893520.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            20246..20563
                     /gene="trxA"
                     /locus_tag="KNP54_002646"
     CDS             20246..20563
                     /gene="trxA"
                     /locus_tag="KNP54_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBF0893521.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            20580..21458
                     /locus_tag="KNP54_002647"
     CDS             20580..21458
                     /locus_tag="KNP54_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBF0893522.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21728..22096
                     /locus_tag="KNP54_002648"
     CDS             21728..22096
                     /locus_tag="KNP54_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBF0893523.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            22099..22470
                     /locus_tag="KNP54_002649"
     CDS             22099..22470
                     /locus_tag="KNP54_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBF0893524.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22615..23070)
                     /locus_tag="KNP54_002650"
     CDS             complement(22615..23070)
                     /locus_tag="KNP54_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893525.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(23109..24374)
                     /locus_tag="KNP54_002651"
     CDS             complement(23109..24374)
                     /locus_tag="KNP54_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBF0893526.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         9516 a         2733 c         3796 g         8587 t
ORIGIN      
        1 aaattaatca atatagtttt ttaatataaa caaaaaataa aaaacttata taaataaaat
       61 gcttgttttt cttgtattat ttatataaat attgaaattt gtctagttat acgtttttat
      121 tgaccagtta tgcagttgat attgaatatt ctaaatattg gtgttatttt ataggtggtt
      181 taaacatatt agggggattt tatatatgat ttgtatgatt tatagagaat gtataaaata
      241 gtaaaggttt agagccatgt ttagtggatt gcagaatatg catatagaat gattcttgta
      301 aattaagtta gacataggaa atatataatt tgtattggat gattaatttt atggtgtatg
      361 cttttaactt ctataatggg aaagtaaaga tgtactccca atacatcttt actttagcag
      421 aagttatagt tacttataaa gtacaaaaaa ttatatattt attagagtag ataaatctaa
      481 aaaggttttt ctagaaaaat ttagttttaa ttgtatctac ttactaataa taagacttga
      541 tgtaagcagg tttcaactac cgtttctcca tattctgata taaaatcatc taactgtgta
      601 tctaaaaaat tacaataatc atatgaacta ctgatgtaag cagttagtat atgtgtacat
      661 ttgtctattt ctccaataaa catattatcc atccccctaa aaaatttagt aaaaataaaa
      721 agtcgcattc tattagtcaa ttaacataat ttataaaatt ttttagtact agtttctata
      781 acttaactcc ttaaggttaa atattcccag ttttaccaat ttagttttat tctacaagta
      841 tataatacta gaagatgctc cattattcaa catgcttgtt tgagaataga aaatattcta
      901 aaattataat tgtttttaaa aataagattc aagataaata aagttatatg caactattta
      961 ataatctttc cataataagg acagtaggtt ctattcttaa aaaactccat ctttaaattt
     1021 aaagaataac tacaatttga acaacaataa aatttccaat caataaaaat atcaaaaata
     1081 ataaaaataa ttgaaaatgt ataatttccc agaaaaataa taaatgtaac tccaataata
     1141 aacacaccta taaattataa aataatttaa gctttattta aggttagtat tatatttata
     1201 taagatttaa gttttaatat atatgtgtaa ttaaaatgat ttaggaggag aaatatattg
     1261 gtaaattggg aaataaaaaa attggctaaa tctaagagta tgtttatatc tctagggata
     1321 ttagtgttaa tactaatgat tagtatcttt attacgcctg ttttagaaac agaaagttat
     1381 tatatagata aagaaaaagg acgtatagaa gatacgagaa gtggtatcga cgtaggtaat
     1441 gagaaatttc aaaataagat taatgtttta aagcagtttt caaatcaaac agatacaggt
     1501 gaattttcta aaaaaattga attaatgtca aagaaaaaac ttgataatct aagtgtgaat
     1561 gaatataagg atattagttt ttggaaagta tttaactata gagtcacaaa ttcacttata
     1621 aatgtaggaa tgttaatcat tatatctata attatatcca atatttatgt agatgaagtc
     1681 gttacttcgg taaaagatat catactatca tcaaaagaga agaaaaaagc attaaagtct
     1741 aaaatatttg ttgctttatt agttccatta gtaatttatt ctgtttattt aatgggaata
     1801 tttattataa cttgtatgca acaaggagta cctgttaatg gagacttaga atcttttaga
     1861 atagtagaca atgtagttgc attgaaaact aatttaagta taacaaagta tgtaatatta
     1921 aatataggca tagagctttt gatgtttgaa ggatgggcca tgatagccat atttgggtct
     1981 tttataagta agtcttcaat atcttcaata agttttttta tatttattat atctataact
     2041 aagataatgt cggtaatcca tatattacct aaaaaattac tttcagttgt atcaaatgta
     2101 aattattatg atttgatatt tggttttaat aaaataatag gaaattatct aggtgatatt
     2161 atgatattta aagtgaatat agacattgtc aatatagcaa taggactttt gatggcaata
     2221 ttgataggtg ctatgtcatt atgtttttta gtaataaaat cagattatat aagtagataa
     2281 aaggggagtt aagatgaata aattagaaat agaaaatctt tcaaagatat atggtaaaaa
     2341 agtagcaaac gacaagatta cagtaactct ggaaaatgga gtttatggtc ttctaggacc
     2401 aaatggagca ggaaaatcta cattaatgaa acaaataaca acgttgataa aacctgatga
     2461 aggtcagata ctttataatg gtgaggatat atttaaaatg gatgctgatt atagaaatat
     2521 tttaggatat ttgccacaag aatttggagt ttataaaaat tttacagcaa aagaattttt
     2581 acagtatatt ggagctttaa aaggtttaag gggaaaatat ttaaatagta agataggaga
     2641 attattagat ttagtaggtc tttatgatgt gagaaataag tctataggaa aattttcagg
     2701 aggtatgaag aggagagttg ggatagcaca agttttacta aacgacccta agataatagt
     2761 ccttgatgag ccaacagcag gacttgaccc acaagaaaga gctagattta ggaatttaat
     2821 agcaaaaatg tctagagata agataataat actttctact catataattt ccgatataga
     2881 atcagttgca aaggaaacaa taatgattaa agatggcaaa ctcctaatga aaggaacaca
     2941 caaagacata ttaagtcaca tggaaaataa agtatataat gttcaagtta aaaatgaatg
     3001 tgaagttgat gatatacaat ctaaatataa ggttgtaagt attcaaagtg atattgattc
     3061 agtagtactt agaattgttt cagaggatat tccaagcgag gataatatac aaccagttca
     3121 agcaaaattc gaagatgtat acatgtttta ttttgattta gaagatgcaa gggaggtgta
     3181 gtagaaatga tgtatttagt taaagctgaa atgataaaaa tattaaaatc aaagagtgtt
     3241 tggataattt ggctgttttt aatatttttt ggattttttc tgattagaaa gtttgatgtt
     3301 ttagatactt atgcagatat attttacaag atagaaggct caatacctct aataggtttg
     3361 ataatgttta taataacttc tggaaattac attaaagaat atgattctaa tatgacaggt
     3421 ttaataaata caactaaaaa gggaaaaaaa tcagtagtat tatcaaaact agtagctaat
     3481 ggattaattt tatctattat taatatttct tttatattgt tagtaggaat tagaggtttt
     3541 agtttttttg attttaaaaa tttaaatgaa tcgattcata acttatggta ctttggaaat
     3601 agtaatttaa atcttacagt aatacaaatg tatataattg ttatattgac tactattttt
     3661 gcttctttta tatttgcaca aataggctta acactttcat ctatatttaa atcggctgta
     3721 attccattta tactaggtgg attgataatg gcaattccat actttagtgt aggttttata
     3781 ccagataaag ctataaaatt tatgtcagtg actccaaatt ggattatgat gagccaacaa
     3841 atggttaagt ataatgtacc aagtattttg atagtttttt ctatagtaat ctcaattata
     3901 ttaatgatag tgttaactaa aataacatat gaaaatttta catcaagcaa aaggttttaa
     3961 ctaaaaataa tagtaatttt atttatattt tagtttaatt aaaaataaga taaatgaatt
     4021 ttagataaaa tatatgctaa tatatatgta aattattaca ggaggttgtt tatggaaaat
     4081 cgtgttttaa taatagatga tgaagtagaa atattgaagc ttttagaaac tgtcctaaaa
     4141 aaagagggcc ttaataatat atatactgca aaaactaaaa aagaaggatt agaattattt
     4201 aaaagtatta atcctgattt gattgtattg gatattatgt taccagatgg cgaaggttat
     4261 gatatttgta aagaaataag aaaaacctcc aattctccaa taatattttt atcagctaaa
     4321 accgaagaat tagataagtt acttggacta gcgattggag gagatgatta tgttacaaaa
     4381 ccttttagcc ctaaggaagt ggcttttaga gttaaagcgc atttgagaag attaagttat
     4441 tttagtgatg ctcaaaacga aagtaaaaat ctaaataata atgaagaaaa aattatatca
     4501 tttggcccat atatattaaa tgaaagtagg gcagaactta taaaagatgg aaaatctata
     4561 ggactgtctg caaaggaact aaaaatccta tctttatttg cacataatca aaatcaaatt
     4621 ataagtaaag aaaaactatg ggataaagtg tggggagaag attatgttgg atttgacaat
     4681 actataatgg ttcatataag aaaaattagg gaaaaattag aggataatcc ttcaaagcct
     4741 gaatatattc tgacaataaa aggtcttgga tataaattag cagtaaagga agattagaat
     4801 atgaagtgga agattactag aaattttata tttacaattg tgtttgtagc tatatcagta
     4861 gtaattataa atatcatatc tatattgtat gtgatttcaa ctaatagttt ttttaaagtt
     4921 gtagattctg gaaataatcc tgaagaattt gcacgttctt ttgaaaaaga tttatatgaa
     4981 aaagatggag aatttaaact atctaagatt ggagctgaaa aattagaaaa atcaaattcc
     5041 tggatacagg ttttaaatga tttaggagag gaagtttatg gagtaaatgt gccaaaggat
     5101 actcccaaaa aatatacacc ctttcaaatg gtgaataatt acaagtatat agaaacaaag
     5161 tatgttaatt ttgtattaga aaaatattta aacaaaaaac atctaaacat aatagtaggt
     5221 atacctagta gagatatatc aagaataatt ttaacctatt ctcaaaataa cattaaaaaa
     5281 actttaaata aagttatcat tataacacta gtaattgata gcgtggtagc tttaggtgta
     5341 ggatatttat ttagtagaaa acttacaaaa ccaatttcaa gcgtactatg gagtattgag
     5401 actatggcta atggaaatta tagtttatat cttaaggaca gaggtatata tgaagaagtt
     5461 tttaaaaata taaatatgtt agctgatact ttaagagtaa atgaagttga gagaaaagaa
     5521 aatgaagagt tgagagagga atggttggca aatataacac atgatataaa gacacctcta
     5581 gcatctatac aagggtatgc agagataatt aatgacaaag attatgagtt tgaagaagat
     5641 gaaatacaag agtatacaga aattatatat aataagtcta agtatataaa agatttagtt
     5701 gatgatttaa atttatctac tcgattaaaa aataatacta tagttctgga caagaaaaaa
     5761 ataaatttag tcagtttagt cagagatata ataattgata ttttaaatga taatagatat
     5821 aaaaatagga atattgaatt tgaaagtaat gaagatttaa ttgaagtata tgtagattca
     5881 atcttattca gaagggctat aaccaatctt atatttaatt caatagttca taatagcgaa
     5941 ggaactttga taagtgtaga aattgtaaaa aaagataata tagaaattat aataaaagat
     6001 gatggaattg gaataagcaa aagtgatttg aaacatattt ttaaaaaata ttatagaggt
     6061 actaatacag gtgagatgca taaaggttca ggtcttggta tggctatttc taaagaaata
     6121 atagagattc ataaaggtaa aatttatgta agtagtgaaa ttggaatagg aacaaaaatt
     6181 attatagaga taaaacaaaa ttaggagata tgatatggat ttttttaaaa aaggtataag
     6241 tgggtttact attaagattt tagcattaat atttatgaca tttgaccata tagcagcatt
     6301 tatgccacaa acaatgcaaa taccaatttg gtttcattgg gtaggcagaa tatcagcacc
     6361 actgtttata ttcatggctg ttgaaggatt ttatcacact agtaacagaa aaaaatatat
     6421 aagtagattg tatatttggt ctgttattat ggctatagga aatcaaataa ttaataatgt
     6481 attttcacat ccagaaggag ctataattat aaataacact ttttcaacat tatttttaat
     6541 agcgatttat ttacaagcaa tagagttcat aaagaaattt agaaaagaga aagaaattaa
     6601 atattttatt ataggattat tgatgataat cattcctata attttaggaa tatttacagt
     6661 agctttactt tttaaagtca ctaacagagt tattgcttta tttatgattt tggtaccagt
     6721 accattttta gtagaaggtg gaccaatttg gattatactt gggattattt tttatttgtg
     6781 tagaggtaaa aagttcagtt tgagtatttg ttatgtttta atgtgtatat ttatatttac
     6841 aacaatgtca aatggagatt atagtttaaa aaattctatt ttacaaaatt accaatggat
     6901 gatgattgct tctctacctt taatgttact ttacaatgga gaaaaaggga agagtatgaa
     6961 gtatttattt tatttatact atccaatcca tgtatatata ttgtatatct taggaatata
     7021 cttaataaat ggtttttgat tgtaagtgat atttttaata caaaatgaac agtatgagga
     7081 ttgttttagg tctattaaaa ttgttattta gatgagattt gtagaatatt taaatttatg
     7141 agcagaaatt cagttattgt aatttcaata acattagaat ataatattat aatttattta
     7201 gaaatatatg atgttataca tggtttggtt attaatgtaa taataaaaca gaggtttgat
     7261 ataaaattca atacctctgt tttagtgctt tttatcctac atttatgctt attttattta
     7321 taaattagtg ttttgtttta attaatatta gtacattttt tatttatttt ataaaattag
     7381 tcataattgt ttcttcatat tgtggttctt taattccagc ttttttacct gctgatatac
     7441 acttaagaag ccatgccatg ttttctccta gagttcgcat agtctgtaat ccttcttcat
     7501 ccttcataac atcctctgga gtaaagccat gtacctggtt ccaatactgt gatgatacaa
     7561 taggcatatt gctgattgaa aaatatttat ttagttggtc aaatgttgca cttgcaccac
     7621 cacgtctaca tgacacaact gaagcaccta attttgtagc catgcgactc ccagctatga
     7681 aaaatagacg gtcaagaaaa gaagttaatt gaccagttgc actagaaaag taaacaggag
     7741 aaccaataat aataccatca atattatcca gatcttcaat caattcatta actttatcat
     7801 ttcgaataca ttttccagtt tcaaaacagg atgcgcaact aatacatcct gggattgttt
     7861 ctttacctaa atacagtatt tctgttttaa tatcgtgttt actcaatact ttagtaatct
     7921 catttagtgc tgtataagta catccatatt ggtttgggct accgtttatc aataaaactt
     7981 tcattataaa tttcctccaa tgaattttat ttaatagatt ttctaagaga cattattttt
     8041 tataaaatag gattttcatg aatattatca atttatatag aaatgtctaa tcttagaatc
     8101 ctatttaaaa taactttttt tttagtaaat acacctccta ttataaaatt gactttcaat
     8161 tattcttaca ctataatttt attataaatt attctaaaaa caagtacgca catttttgtt
     8221 caatactaac caaaaggaga gtgtaatata tgagtataga ctgtatatca aatacagatt
     8281 taagtgaaac aggatttagt tatacacttt cactgattag tggtaaatat aagatgataa
     8341 ttctttactg tcttgtagaa tttgaagttg taagatataa tgcattaaaa cgttatataa
     8401 atactatctc ctataaaact ttgagtttat cattaaaaga attagaagca gataacttga
     8461 ttattcgtac tgaatatcct caaatacctc ctaaggtaga atatagtcta tcagaaaggg
     8521 gaaaatctct gattccaatt ttagatgcaa tgtgtgagtg gggagagagg aatagacctt
     8581 aattttgtat ctgtagatac cataaaaaga ctgtgagtaa aattgtttga ataatctact
     8641 cacagtctat atttaaatta atagttagta tttttaattt ataaaaatac taaaaaattt
     8701 attatgaaat ttcaccacca atttctttta catcttcttt atatataata caagcttcta
     8761 tagctaattc taagcctttt actatttctt ctaaagacat gaatggtgta ttttttttat
     8821 ctattacttg tgaagttgta tatgggatgt gtataaatcc accccttata ttaggatatt
     8881 tcttgtctat catataaaga attccataca tcacatgatt gcaaacaaat gttcctgcag
     8941 tgtttgaaac actagctgga attttatttt cattcatatg ttttaccata gcttttacag
     9001 gcaattttga aaaatatgca ggttcaccat cttcttttat aatagtatct ataacctggt
     9061 taccctcatt atcttttatt ctaaaatcat ctatatttat agcaactctc tcaggtgtaa
     9121 tgtcaaatct acctccagct tgtccaactg atattactat atctggattg tgctcttgaa
     9181 tagctttatc tatagcttca acagattttg tcataactgt tggtatagtt atctttatga
     9241 tttctgcacc gtttatatta ttattgaccc tttcaactgc ttcttgagct gggtttattg
     9301 gttctccgcc aaatgggtca aatcctgtta acaaaatttt cattatttta cctcctaatt
     9361 atattaaaat cctaaaaagt acattactaa tatgtgggct ataattaata ccaaagcaac
     9421 tggagcttga tattttataa caatataatc atttttacat tctagcaagg ctgctggaac
     9481 tatattaaaa ttagcagcca ttggagtaag tagagttcca caatatcctg ctgttaatgc
     9541 taatgctcca attatagcag gatttccacc ttgagacaat acaaaaggaa taccaattcc
     9601 tgccgttatg actgaaaatg cggcaaatgc atttcccatt atcatggtaa atataaccat
     9661 acctaataca taagctataa caccaaataa tctgctatca gcagggacta caccagatat
     9721 catggttgaa ataacttcac cgactccggc ttgagtaaat aaagctccca atgcaactaa
     9781 aagttgtggt aacatactag caggtcccat ttgttgaagt aatcttgagc catcttgaac
     9841 tgatgtagca ggttttgcct tagttattat aagggctgat attaatgcaa ttattgaacc
     9901 cacacctatt gcaaactgag aagaattatc aaaattagaa agactcatag ctactactac
     9961 tgcagcaaat gctaatatta atgatggtat aaatatttta tttttaagtt tgtctgcttg
    10021 ttcttttcca aaattttcat ctggttcttc atactttgca aatacaactt gtttagaaag
    10081 tgttaataaa ctagataata ttaatattat tcctattata ttggctggaa tcaatctacc
    10141 aaatatgaat ggcagtgata taagtatcca aaataatgat gtaccatatt tcttattgtt
    10201 atttatggta gtaaaagact tatatgctat aacaatcatt aaaaatccca ttagtgcgta
    10261 aaagatttcc aatgatatgt ttataaaatt ttgcattttt attcctccta aataaaacta
    10321 ttttttatga cttttgttta attttttatc atataaggta aactggattg tagccactac
    10381 aagtgctatt actgccataa tagtactagc ctttacgata ttaagtccag ttacattgta
    10441 tccaaattga gtcagagtag atgctataag taatactcca ctactacctg caaataagtt
    10501 ttgaccataa aaatttccat agttttctga tgcagcagat aatgccttta tggcttcttc
    10561 atccgattct tttagttcat cactattact taaaccagca gcttgtgcca taggattaac
    10621 aagtggtctt acaaattgag gatgtccact cattcttatt gatagagcac cagctatttg
    10681 tctagctatc atgtatatag taagtacttt tcctgttgta agtcttttta atttttctat
    10741 taaagaaaca gctctttgtc ttaaaccata tctttctaat acaccgatta ctggcaatgt
    10801 taatatgaat aatgatacac ctctgtttga gacaaaagaa tctcctaaaa ttgtaaaaat
    10861 ttgattaaaa tctaatcctg caacaattcc tgttgccact cctgctaata atacagtaaa
    10921 tagtgtgtca attttaagta taaatccaat tacaactatc aatataccga ttagttttat
    10981 cataaattgt tctccttcca tttctatatg ttttaattta aatttattta atggataaag
    11041 ttaaactctt tttatagtat ttgcgttaat aggactatta ttataaaatt taataaaaaa
    11101 tagggaagat gttttaaagt atcaaagtaa ataatggttg tgtataggaa tttgaataac
    11161 aaagattata ttttaagcta atatgaattg attttgtaag tctatagttt aagtatatgt
    11221 caatatttga aatagtagtt ttaaattaaa cattatatta taaaaagaga atgtgccaaa
    11281 catagagaca agtgtatttt tctctgttga aatgataaaa atatatttga tttcatacaa
    11341 aaagagagtg tctaatgaat tttttagttc attagacact ctctttttgt tatgattaat
    11401 aaaacatatt tgttatgatt aataaagcat atattaagtg ctagtttcat tagatttcac
    11461 taagaaaaat aaaattttga taaagtttaa agactatttt gagcaatatt acttataaat
    11521 aaaagaattt atcatagaaa taattagctt tattttagct attaagattt attaaaaaat
    11581 tatctatatt atcctgtgat attctaaaac tgtcataatt accttttgaa acagccttca
    11641 taataagttt atctaaaaat ttcatttttt ctaatcgagc ttcactacca aaaattccaa
    11701 tagcatttgc actttctaat aaggatgatg gaaaatttga ttttaaatat ttatctgctt
    11761 gttcagaaaa gccacagcaa aggaaaatgc caacttgttt tttgtttaat aactctacat
    11821 tatcattaca tagcacctgt attttttttg aaactgaacc aacatatata gaacttccaa
    11881 taataatttt atcaaatttt gataactcaa ttttattatt attattatta atatcaacaa
    11941 tagtgacatt atctgatagt ttatttttta gtatatttgc acagtctttt gtacaaccat
    12001 atttacttga atatataata atagtattca taattattct ccctttctta aagcattttc
    12061 tacagctttt cgtatagtat tactgctata agttgcagaa gttatagcat ccacatctaa
    12121 agactgttgt ttaataatac ttgttgtaat tttttcagca ggtttaccta aaagatggtc
    12181 gtgttttaag atattaatat tttggatttt accattatta acttcaacag acacagtagc
    12241 ttttaccaag ttattatcag cacttccagt ataaatgcca tttttaacat tattaatatc
    12301 tatatctttt actaccaagt tttctggctt taagttgctt acaattacaa taataatgca
    12361 tataaataca aagaatagag caatagatat ttttacatat tttttctttt tattagtagc
    12421 cttgttgcga attttcattg taaagtcctc ccactaaaat atctaagaaa ttttctataa
    12481 gttgagaaaa attatgtaaa gaatatagtt tattttcaac aacacataaa acgaatccta
    12541 acaatgcact tataagcatc catgagcttt tatctatatt ttttttgaat attccttgtt
    12601 caattccaat ggaaaggaat ttatcaagca tttttatacc attattgcta ggcgtattgt
    12661 ttgtattttc agatgcaaat ataatattca ttctactatg catgatagat tttgccatct
    12721 ctggttcact agaaagagtt tttataaagc tagtcataat ttctatgatt tgtttatcta
    12781 ttggtagtga tgagcaatta ttcataatgt caatggcatt actttctact gtgttataaa
    12841 gtttattggt catatcgctg ataatctctg ctttgtcttt gtagtaaaga taaattgtag
    12901 ttggagaata ttctattttt gtagcaattt ttcttattga taaattttca tatccatgtt
    12961 ggtttataat ttcgatgcta gcatccataa tctttttctt catttcttct ttttcatttt
    13021 tacgtctttc tttgatactc atataatcac ctctttgctt aacggtgtta agttaattta
    13081 cactgttatt gtataattta attttaatac tgtcaataaa ttattaaata atataagtta
    13141 atatattttt atggataata aattaatgtt attaattgta atatttaaga tattattgta
    13201 taataataat cggtttaaat gcgccacatc ttattaaagt tggttcataa ttctaaataa
    13261 actttaataa gatacattaa aatataataa attcttttat gctataaaat ttattttata
    13321 gctattaaat cagatgttta aaaatttttt aacggtctat agtttttaag agtcttatag
    13381 taagtagcct aaaaatatga ttttacatct gtacttgttc gagaactcca agtataaaaa
    13441 actaaggaat tatatagtgg cagtatataa ttaataccct tagacacacc tttttgaaag
    13501 tggaaaaaag atgtgtagtt ctcctcgacc acaaatcaag gaggataaaa aatggaaaag
    13561 agaaaagtaa taattgattg tgacccagga attgatgatt ctttggcaat tcttctggct
    13621 ttaaactcac cagagctaga agtaattgga attaccacat gttgtggaaa tgtcccagca
    13681 aatataggtg cagaaaatgc actaaaaaca cttcaaatgt gttcttcact aaatattcca
    13741 gtatatatag gagaagaagc accactaaaa agaaaacttg taacagctca agatacacat
    13801 ggagaagatg gtattggaga aaacttttat caaaaggttg taggagctaa agcaaaaaat
    13861 ggagcagtgg attttataat aaatacttta tataatcatg aaaaagtatc aataatagca
    13921 cttgcaccac ttacaaatat agctaaagca cttattaaag ataagaaagc atttgaaaat
    13981 ctcgatgagt ttgtatctat gggaggagca tttaggattc atggaaattg ctctccagta
    14041 gcagagttta attattgggt agacccacat ggagcagatt atgtttacaa gaatttatct
    14101 aaaaaaatcc acatggtagg tttagatgta actagaaaaa ttgtacttac tcctaatatt
    14161 attgagttta taaatagact tgataagaag atggcaaagt atataactga aataactaga
    14221 ttttatattg atttccattg ggaacaggag ggaataattg gctgtgtgat aaatgaccct
    14281 ctagcagtag catactttat agatagaagt atatgtaaag gatttgaatc atatgtagaa
    14341 gttgtagaag atggaatagc tatgggtcag tctatagtgg attctttcaa tttctataaa
    14401 aaaaatccta atgcaattgt tctaaatgaa gttgatgaga agaaatttat gtacatgttt
    14461 ttaaagaggc tttttaaagg ttatgaagac attatagact ctgtggaagg agtgatatag
    14521 tgtgaaaaga aaaatatgtg taaaaactat tacacttata gcttttggta tttctataaa
    14581 tataataggc gcttttatag ctatgggatt aagattacct gtatacttag attcaatagg
    14641 aactataatg atagcttcac ttttaggacc taaatacgct gttgttacag gtgtgtttgg
    14701 aagtttaata agtggaatta cgtttgatgt gtattctctc tattttgcac cagttcaaat
    14761 atcaaccgga ttacttgctg gaatagcatt taaaaagaat tttttaaggg gtttaaaaac
    14821 tccactagga gtacttttat ttgccattcc aacatctata ataagttcaa taatttcagc
    14881 atttttattt ggaggtatga cctcttcagg ttcatcatat atagtgcaaa tcttgaaagt
    14941 gttaggactg ggggatgttt ttagtgtgtt tgtaacccaa gtatttactg attatggaga
    15001 taagctgtta gcagttgttt tagtgaattt aggattaaat gcagttccaa aaactttaaa
    15061 ggtatcattg actggaggaa aatagataga aaatggatag atatagtgag ataacaaata
    15121 aaaatcaaag agaaattgtt ctgcttaaag gatttccttg tatatgggga aagtgttctt
    15181 tttgtgatta tatagatgat aattctaatt tagaagaaga gatgaataaa ttaaatctaa
    15241 aggttttaaa aaacgtaact gggaaatatg gagttcttga agtcataaat tctggaagct
    15301 gttttgaatt acctaaggat actttagaaa aaataaagtg tattataaaa gagaagaata
    15361 taaaaaaatt atttttagaa agtcattggt cttacaaaaa taggcttaag gaaatgagag
    15421 agtattttga aattcctgtg gtatttaaaa ttggagttga aacctttgac aatgatttta
    15481 gaaataatat tttaaataaa aatgcaaatt ttaagactcc acaagatgta aaagaatatt
    15541 ttgattcacc ttgtattatg gttggaataa aaggacaaac aaaagagatg atagataaag
    15601 atatagagat tatcctaaat acttttgaaa aagcgacagt gaatgttttt ataaataatt
    15661 cttctagtat aaaaagagat gaagagttag tgaaatggtt tgttagtaag tataaattct
    15721 tggatgaaaa tccaaatata gaagttttat acaataatac agactttggt gtaggagatt
    15781 agcattaatt tagtttaaat ttaaaattga aaagtttctt atgtttttga aaaagcttct
    15841 aatagttaga agcttttttt gtagagtttt atgttacaat aagaaaaaag gaattaagga
    15901 gcaattaaat gatgtttgat aggggaaaat ggaataaatt ggattataat gaacttttag
    15961 aatatatgat gtctatacaa gatataaaat atagagattt taataaaaag cttatacctg
    16021 gaacagaaaa tataataggt attagagttc ctaatttaag aaagttatca aaagaaataa
    16081 gccaagggaa ttggaaggaa tttttagaag tagcacagga tacatactat gaagaagtta
    16141 ggctacaagg tatggtaatt ggcaatataa atagtaattt tgaagaaact ttatactatg
    16201 taaaaagatt tatacctaaa atcgataatt ggtcagtttg cgatggattt tgttctgatt
    16261 taaagtctat gaaaaaatat aaagaaaata tgtatgatat acttaaaaaa tatgtttatt
    16321 caaagaatcc atgggaaatt agatttgcat tagttatgtt tttaatatat tatgttgatg
    16381 ataaacatat taaagaaata tttgaatact gtaataatat acaaagtgaa gaatattatg
    16441 ttaaaatggg tatggcatgg ttgctatcaa tttgttttat taaatgtgaa gaggaaactt
    16501 ttctctatat aaaaaataat aatttagatg atttcactta taataaaatg ctacaaaaaa
    16561 taattgaatc aaatagagta gatttagaaa agaagaatat aataagaagt atgaaaagaa
    16621 agacaagaag atgttgacgg aggaatatta atgaataaca atgaagacag aattgacaaa
    16681 tttttagaac ttcaaagcaa aggatttaaa tttgcagaga tagctcaaaa tctaaagatt
    16741 agtcaaagta ctttaagaac ttttttaaat aaaaaaggat ataagtcaga aaaaggtaaa
    16801 tacatattaa aagacgaatt aaattataat aaaagtttgg ataatagaaa cttggaagaa
    16861 gagaaagcta aggagtatga aaaaagtaaa aagaatacta taagtaatag aaaaaaagta
    16921 agcaccaaaa aaaagatttc taatgaaaag gctttaagta aaagtgttga acaaattgag
    16981 tttaatgata caggtttaaa aaatgcaaag ccaaaacaaa atattaagcc taagaaagat
    17041 agaaaaataa atataactca agaagattta gataagcttt gtgaagtata tgattggtat
    17101 ttagaagtaa aagattacaa tataaagcct aaaaaagtat ctaataaaaa agatgtacat
    17161 atagatgatg aacacataga tgaattaaaa acaacaagaa tacgtataga taaagaaata
    17221 tggaatgatt ttgaaagatt atgtagtaat tcgaattttg aaaaacatca aatacttaca
    17281 caggcattga aagaatttat gaaaaagtat aaaaatctac tataaaatac tactatatga
    17341 ggtgcttaat atgaataaaa tagtaaaaaa atcaatttct ctaatgatta tattaacaat
    17401 atttattttt atgttgacag catgtgaaaa agatgaacag cctgattcag ttgatattca
    17461 aacagaagat aaaaatgaga taaaaataga tgagggaaat gcaaaagtat tgaatatagg
    17521 aaaatcagaa attataaata tagatgaagg tgataaagta gatacatcaa caaaggtaga
    17581 aaataattca acatttaata tatccaatgt tgaattgata tataatgaat atgatgagaa
    17641 taaaaaaatt atatcttcgg atagtaaggc tttgttggac atgactttaa tgcctgggaa
    17701 agttgcttac atagaatgtg ggcataaaac ttttgtaaag ggtgtagaag tttatgcata
    17761 tgaatatgag gcagagggta agattgtgta tgttaattta aaagaaaata ctattaatat
    17821 aagaaataat aatattaagc tagaaaatag tagtcagtat gaggtgctat ctacatcaga
    17881 acttaaaaaa gtaaatgaat caaatgaggg aattacgtat caagtaaaag taaaaaattc
    17941 atcatcaaaa gatttaggaa atattattct taagacagca gaagttaatg aaaatggaga
    18001 atatttaaca gtaaatcgtg taccatcata taagatttta aagccttcag aagagacaga
    18061 tatagatata ttgtgttcaa caaaggcaaa aagtgttgaa atagtgggat atacgtatga
    18121 tgatataaaa gaaaaagcca atgtggatat tgacttaaaa tctcataaag ttaagataga
    18181 caaataaagg taggggatac ttatgaaggt tttaatagtt gaagataata agatactttt
    18241 agaaagtgta gtagaagaac ttagcaagca ttttgaaact gaaaagtgtg aagatggaga
    18301 agaagcttta tacttaataa atcaaaatat atatgattta gtcattttag acttaatgct
    18361 tcctaatata aatggatttg atatcctaaa gaaaatgaga attaataata tagatacacc
    18421 tgtacttata ttgacagcaa aagaaacatt agatgacaaa gtagaagcat ttactatagg
    18481 agctaatgat tatttgacaa aaccttttta tatggaagag ttagtagcta gggtatacgc
    18541 tatattaagg actaatggaa agataaaaga aagaaacgga ttagaattta aatctttata
    18601 tttagataca ctagaaaaaa gagtgtatat tgaaaaagaa gaaataaaac ttcaaaacaa
    18661 acagtttaac ttgcttgagt attttgtatt aaataaaggt tcaattttat taaaagagca
    18721 gatttatgat agaatatggg gaattgattc agatgcaact attgaaatag tggaagtata
    18781 tgtaagtaat ctaagaaaaa agctaagtaa atatggatat gataaatata ttaaaactaa
    18841 acgtaaggta ggatatatat tcgatgataa ataagaatgt atttaccagt actaaaaatc
    18901 atttaataaa aatgtatatt attgtagtag gtagtttttt aataatcttt tctatattta
    18961 tatactcata ttttagggga cttacatata gtggaattga tagtgagata aatgatgaac
    19021 ttgaatatat agtctctcaa tttaaaagaa cttcattttt gaacccaata agactcaaag
    19081 atcctaaaga tatggtgtat gtatatgaag atggaaggat aagttactat actcaaaatg
    19141 aatattttga tgagttactt ccagatagaa gactagataa aaaaaattcg ttttttaaat
    19201 acacagaaaa tggatatact tttagagaat taaatgtaga tgtaggtaga taccaaatac
    19261 agataattag aaatatagat tctgagatga attctttaag acagcttaca tctgttctta
    19321 taattggaat attaatttct gtaataatta cttactttgt ggctgtatat ctcactagaa
    19381 aagctttaat tccaatagaa acagcatgga aaaatcaagc taagtttata caagatgctt
    19441 ctcatgaatt aagaacacca ataacaatag tttcatcaaa attagaaagt atgttaaaat
    19501 ccccagaaag tacagtaaat gatgaagttg aaacaatagc tactgcaatg aaggaaacta
    19561 gaagacttaa aaaaatgata actgatttat tgtctcttac taaagaggac tctattgtta
    19621 aagttaattt agaagaaata gatttagaaa agttattgga agaaatatca gaagactata
    19681 ttgacattgc tgagtttcag gaaaaaagat tcgtgtttaa ttctaaactg aagaataaag
    19741 ttataataac agataaaaat aaattaagac aacttatatt aattttcatt gataatgcct
    19801 ttaagtatac aaaattgggt gatgagatag cattagaatt gaaagaagat atagaggatg
    19861 aggtaacttt acttataagt gatactggta taggcataaa aaaagaagag atacctctta
    19921 tatttgatag attttttaga agtgaaaatg taagaaataa agatttagaa ggttctggaa
    19981 taggactttc aatagctcgc atgattagtt taaacttatc tattgatata aatgtaactt
    20041 ctgatgtaga tattggaact acatttgaat tgtcaatacc aaaaaagtta aaataataaa
    20101 aatataaaaa attgttttta gaaatgaaga atgggtatac taattagtat aaaatataaa
    20161 aagaccttat aaaagtaaat ttatatttat aaatttcata gtataattat atagggataa
    20221 taaagtttaa taggaggatt taaaaatggc aaaagttata aatacatctg aatttagaag
    20281 tagtgttgaa ggtagtaagg gagtagttgt agttgatttc tttgcaactt ggtgtggacc
    20341 ttgtaacatg ttgggacctg tatttgcaga attaggtgaa gagatgaagg ataaagctag
    20401 atttgtaaaa gttgatatag atgagagttt agaaatagct caacaattca atgtatctac
    20461 agtaccaact atgattatat ttaaagatgg aaaaccagta gaaactttaa ttggattcat
    20521 gccaaagaac aaaattgaaa tgcaagtaaa atcatattta taaaaaatgg gtgagtatta
    20581 tgagatatga tatagctata atcggcagtg gtccagctgg attgtctgct gctataaatg
    20641 caaaaataag aaataaaaca attatcatgt ttggtaatga taatttaagt aataagcttg
    20701 ttaaagctcc ttcaatagat aattatttag gtttttatga tataagtggt gatgaattaa
    20761 aagacaagtt taaatcacat atagatagta tggatatttc aattgaaaat aaaagaataa
    20821 ataatattta tgctatggga gaatacttta caataatgtc tggaaatgat atgtatgaag
    20881 ctactactgt aatccttgca actggggtag agtatactag accaatcaag ggtgaagaag
    20941 aatttctagg aagaggtgtg ggctactgtg ctacatgtga tgcaccactt tatagaaata
    21001 aaaaggtagc agttatagga tataatgaag aatctaaaga agaagcaaat tttttaagtg
    21061 aactcacttc aaagacttat tttataccta tgtacaaaaa agataatctt atgagaagtt
    21121 cagataacct agatgattct attgaagtta tacatgacag accagtacag atagatggag
    21181 ataaacttgt aaacaaagta tcttttaaag aaaaccacat tgaagttgat ggagtattcg
    21241 ttataaaaga tagtacggct ccaagtgcat tggttcctgg aatagagatt gatggcattc
    21301 atattaaagt tgacaataat atgaagacta gtatagatgg atgctttgct gctggagatt
    21361 gtgttggaaa accctattct tatataaaag cagctggtca agggcaaata gcagctttaa
    21421 atgctgttta ctatttagat aaattaaaga gggcttaata tttatattga ttaacttttt
    21481 aaagatattt ataaaaaact gtcttgaaat aattttatta tttcaagaca gttttttatt
    21541 tttaagttat taataaaagt attttaaaat ctatatgtaa ttacttttat taataaaact
    21601 caaagttata ttagtaaaaa ttggaattat ttataatata ctccaaaatt taaaaataat
    21661 ggttgaaaaa tctaattaag agtactataa tttaattaag taattactta atcaaaatga
    21721 ggtacttatg gaaaacttgg ttaaaatatt taaagcattg agtgatgaaa ctagacttaa
    21781 catacttata ttagtatcca agagaaatat atgtcaaaag gggatttcta aatatctagg
    21841 gatttcagat tctgctgttt cacaacatat aaaaatatta aaagatgttg ggataataac
    21901 aggatataaa gaaggatact atgttttata tcatattaat aaagaatcat ttaatatatg
    21961 tgtagatttt ataaattcta tgttaagtaa ttctagtgaa agctttatag atgtatttga
    22021 tgtaaataca atacatctag gatgcagtaa agaatgtaaa tctataaaaa aatgttgtaa
    22081 gagaagggag aaataataat gaaagtatgt ataccagtag aggagaataa aggattggat
    22141 agtaaaccat atggacattt tggttctgct ccaatttttg ttgtgtgtga tttagaaagt
    22201 ggagaagtta aatctttaga taatggagat ttagatcatg aacatggaaa atgtcaacca
    22261 ttaaaagcat tgtcagggac agctgtagat gcagtagttg ttggaggaat aggacaagga
    22321 gctataatta aattaaatgg aatgggaata aaagtttaca gagcagaagg tgatactata
    22381 agtgctaatt tagacttact taaaaatgga aaattagtag aatttccatc agaccatact
    22441 tgctcacatg acggatgtgg acatcattaa aaaaaaacag ctgatgaaat atatacttca
    22501 tcagctattt tttcttttaa taaatacgat tttattcttt taaaaccaaa atttagattt
    22561 ttatgttttt tgtagtatcc ttaataatat ttcaagttta caagtttact acttttagat
    22621 tttttttgta tgtttttcta tatagtcaat atcatttaat atgtcattga gttctttatt
    22681 aagtgttttt aaatcatcac catctacatt gtagtttaaa aatagttcct ctacattatc
    22741 aatgatagaa ttgacttttc tagtaacttc aacaaatgtc ttaaagttac tactattttt
    22801 agcatttaga aattttttta aatcctttga tataaatgat actatttcat attcatcatt
    22861 aaatagacct ctaccaatag gatatggttc aattctctgt aaaaaatatt ggtctttagc
    22921 attaatatta taagtataag atatttccca accgtctcct aaatcaaact tgataaaata
    22981 taatgtacta cttacttttg atattcttgt ggcaccaagc tgtcttaaaa gaacttcaat
    23041 cgaatcacct tgaacagtat taatattcat atatacacat cccctttagt attattatac
    23101 tatatttttt aaaattttat aattaaataa acagtagata taataataga tataatcata
    23161 agtggaaaac ctattttgaa atactcctta aaagagatag gatgaccgtg tttattacct
    23221 atacctgcta gtacaacatt agcagatgct cctattagtg ttccatttcc tccaagacaa
    23281 gctccaagag atgttgccca ccatagtggc attacatcaa taccttcagc ttgcatagtc
    23341 aaaataagag gaattagtgt tgcaacaaat ggaatattat ctaagaaaga agagactata
    23401 gctgacaacc ataatatcaa caacattgta aatacaagat gtccttctgt aagtccaatc
    23461 aatgcttgag ccaatttgtt tattatccca acttctacta atccaccaac tactacaaat
    23521 aatcccataa agaataaaat tgtagaccat tcaatacctg ccataatttc atctacatct
    23581 tgttttccta ttaaaagcat tatagatgct cctgtcagtg ctacaacaga agaatctatg
    23641 tggattgtac tgtgaaacat aaaaccaaaa agtatgaatg ctattaatat aaggcttttt
    23701 ataagtagag gtttatcttt aacagatttt ttttcatcta gttttaatat tgcattttta
    23761 gctctttcat tcacaacaag ttcttttcca taaataaatc taaagcatat tatagttata
    23821 gcaagtatta ctataacagc aggacctaaa tttattacaa aatccataaa actaagattg
    23881 gcagcactac caatcataat atttggaggg tctcctataa gagtagctgt tcctcctata
    23941 tttgaagcta aaatctgtgt tattaaaaat ggaactggat taagtcctaa tatttgtgta
    24001 ataactatag tcattggtcc aataagtaag acggttgtaa cattatctaa tacagctgat
    24061 aaaatagctg ttataatagc aaaacaaatc attatcttcc atgggtcacc tttggctttc
    24121 tttgcagtcc agatagctat atattcaaat aaccccgagt ttttgacaac agctacaaat
    24181 agcatcatac caactaatac accaatagta ttgaaatcta tatggcttaa tccttcatca
    24241 agtgtaagta tattgaatat tatcattaat agtgcaccac caacagctgc tacggatctg
    24301 tttacctttt ctgtaataat agctgccata actattaaaa atatacatat agctattatt
    24361 tgttgaaatt ccataatata agtacctcca tttgtattat tttgtgccta atgctagtac
    24421 tatatatagt attacttttt tattgttttt tcaatggatg tatgaaagta tattatttaa
    24481 caaagttttt ggaaaattga cagaatttaa agaaaatttt tgttatttaa ataaatttta
    24541 aaattattcc attgataata atattaaacg acaaacgaaa aaatataccc tttaaactag
    24601 aatttattgt atctaataac aattataaaa ta
//
LOCUS       DAEHWO010000055        24290 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEHWO010000055 DAEHWO010000000
VERSION     DAEHWO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24290
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.055"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            301..747
                     /locus_tag="KNP54_002652"
     CDS             301..747
                     /locus_tag="KNP54_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893527.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIHTYCKHQVS"
     gene            1128..2045
                     /gene="pstC"
                     /locus_tag="KNP54_002653"
     CDS             1128..2045
                     /gene="pstC"
                     /locus_tag="KNP54_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBF0893528.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            2047..2871
                     /gene="pstA"
                     /locus_tag="KNP54_002654"
     CDS             2047..2871
                     /gene="pstA"
                     /locus_tag="KNP54_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBF0893529.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            2890..3654
                     /gene="pstB"
                     /locus_tag="KNP54_002655"
     CDS             2890..3654
                     /gene="pstB"
                     /locus_tag="KNP54_002655"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBF0893530.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            3682..4335
                     /gene="phoU"
                     /locus_tag="KNP54_002656"
     CDS             3682..4335
                     /gene="phoU"
                     /locus_tag="KNP54_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBF0893531.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            4493..5362
                     /locus_tag="KNP54_002657"
     CDS             4493..5362
                     /locus_tag="KNP54_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBF0893532.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            5449..6885
                     /locus_tag="KNP54_002658"
     CDS             5449..6885
                     /locus_tag="KNP54_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBF0893533.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     NLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            6933..7760
                     /locus_tag="KNP54_002659"
     CDS             6933..7760
                     /locus_tag="KNP54_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBF0893534.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    8056..8318
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8394..11060
                     /locus_tag="KNP54_002660"
     CDS             8394..11060
                     /locus_tag="KNP54_002660"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBF0893535.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            11485..12195
                     /gene="rgaR"
                     /locus_tag="KNP54_002661"
     CDS             11485..12195
                     /gene="rgaR"
                     /locus_tag="KNP54_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBF0893536.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            13241..14272
                     /locus_tag="KNP54_002662"
     CDS             13241..14272
                     /locus_tag="KNP54_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBF0893537.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            14405..15703
                     /locus_tag="KNP54_002663"
     CDS             14405..15703
                     /locus_tag="KNP54_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBF0893538.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLSHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(15817..16062)
                     /locus_tag="KNP54_002664"
     CDS             complement(15817..16062)
                     /locus_tag="KNP54_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBF0893539.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            16210..17076
                     /locus_tag="KNP54_002665"
     CDS             16210..17076
                     /locus_tag="KNP54_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBF0893540.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(17080..17616)
                     /locus_tag="KNP54_002666"
     CDS             complement(17080..17616)
                     /locus_tag="KNP54_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBF0893541.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(17807..18010)
                     /locus_tag="KNP54_002667"
     CDS             complement(17807..18010)
                     /locus_tag="KNP54_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBF0893542.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            18301..19065
                     /locus_tag="KNP54_002668"
     CDS             18301..19065
                     /locus_tag="KNP54_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBF0893543.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            19454..20767
                     /gene="prdC"
                     /locus_tag="KNP54_002669"
     CDS             19454..20767
                     /gene="prdC"
                     /locus_tag="KNP54_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBF0893544.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      21172..21257
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            21839..24013
                     /locus_tag="KNP54_002670"
     CDS             21839..24013
                     /locus_tag="KNP54_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBF0893545.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQTPDVEKPSDGQ
                     MPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEED
                     VKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTL
                     TFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQE
                     NQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWIILGQMDEQERL
                     KQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAGREELKPNDTGK
                     PSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLRLPDGVTAYDGDGNIIGTGEVE
                     ISTQQKFKLKSVVKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQN
                     LLSYTIEKKNGQEVNFNIGLPTDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPP
                     MDDTIINPPVPPTEDAVLNPPVPPTEDAVLNPPVPPTEDTVLNPPVPSVSDTVEKTPE
                     LSRDDTIIKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
BASE COUNT         9705 a         2589 c         4297 g         7699 t
ORIGIN      
        1 aaatctatat attatttttt tacctttaat atatattaaa taataaaata gttaaataat
       61 aagattaaga atttcttaat aaatccagaa gatgctttcg attatataat attttatatt
      121 tttatattat taattatata tgttgcaatt gctgcaccta ctttttctgg tgagtatcag
      181 acacaatcag atagcatcct tcgttgtacg aaacatggac atatttgtct agcgtttact
      241 aaaatattag ctctattttc tatatttata ataatgtttg ttatatgtat ttctatctat
      301 ttggcaattt ctgatttagc ttttggtact gaatgtttga aaacctcatt tcaaatgttg
      361 ttttctgtca ttagtctagt aaatataaat ttactacaag cacagattct tatagctatt
      421 ggtggtctaa tttcaatact tgcaatggtt agtttaacat tatttttatc tgcaaaatgt
      481 aaggattctc ttacttctat gctgattgct ttttctattt gcttaattcc tatgggaata
      541 ggtgttagtt ggattggata cctattaccg ccagggggaa ttggttttaa gattagttta
      601 ttatatcaaa tgacatcatt taatttctta cacttaggag gtatgagttt ttggacacca
      661 cacattatac tgtttttctc agtgatagaa atacctattt ttatattttt ggctattcat
      721 acctattgca aacatcaagt atcgtaacaa tttgatggaa ataatagtga tataaactag
      781 aggatacaat aattatatat gtagtataaa agttaaattt agttaacaaa tcttaatagc
      841 agatataggt aataaattat acataaactg tattattatc tatatctgct attttaatat
      901 agagaaacaa cagtatattg taaagtaaat gtcaaatata gttttaaaag taaaattaat
      961 gttaaaaagt aaatataatt ttacacttgc ttaacttaat cctaatatag atttaactta
     1021 aaaaaagtag aataaaagta caggaaattt gatgaagacg aattataaaa aattaaattt
     1081 tgaatacaga acgaaaatcg ataagtatat tttaatggga gggtattatg atagtaaaat
     1141 ctagattagt aggtttagaa aaaaatgaca ataatggcaa taagacaaaa tacgtaattg
     1201 aaaaagtagc aaaaaatatt tttctactta gtgctttagt agcagttgca agtttacttt
     1261 tgataatagg atttgtattt tataaaggat taagaccatt tatatttgaa ggatattcat
     1321 ttatagactt tttaactggt gcagattggg ttccttctgc caataaattt ggaatatcat
     1381 ctatgatagt agcatcaata tttgcaacac ttggagcact tgttatagga gtacctgttg
     1441 gtatattaac ctctgtattt atagcagaag tagcacctaa aagattagca aaaataatgt
     1501 caccagcagt tgaactttta gcaggtatac cttcagtatt atatggtgta tttggtcttg
     1561 cagtgatagt tccaactata caaagtatat ttaatcttcc aaaaggtcaa agtttgttag
     1621 caatagtaat agtattagca gtaatgatgt taccaacaat aatatctgta tcagaaacag
     1681 caataagagc agtaccaaaa gcatacaaag aaggttcatt agcacttggt gcatcaaaaa
     1741 tagaaacaat attcaaagtt gtattacctg ctgcaaaatc tggagtatta gccgcagtag
     1801 tgttaggagt aggaagagct ttaggtgaaa caatggcagt aatacttgtt gcaggcaact
     1861 caccagttat gccaactgca ataacagata gtgtaagacc acttacaact aatatagcac
     1921 ttgaaatggg atacgcattt ggtacacatc aagaaatgct atttgcaact ggagtagtat
     1981 tgtttacatt tatattaatt ttaaacttag ttttaaataa actttcaaat aaggcggtaa
     2041 attaagatga gaaagttcaa agagaatcta ttgaagtcat tagtatatct atcagcacta
     2101 tttacaatag tatcattagt agttatagtg ggatttatat ttataaaggg aattggcaac
     2161 atgaatttta atttcttatt tagcaattat tcagcatcag gtgatggtgg tatacttcca
     2221 atgataatta caacattata tacagtagta gtttctatag ttgtagcaac tcctatagga
     2281 atattggctg ctatatattt acaagaatat gctaaaaaag gaaaagcagt tacagctata
     2341 agatttgcaa ctgaaagttt atcagggata ccatctatag tatatggatt atttggagga
     2401 attttctttg tagttacatt aaaaatggga tattccatag ttgcaggttc acttacagtt
     2461 gcaataataa tattaccagt aataattcgt acaacagaag aagctttaaa aacagttcct
     2521 caagcttata gagaatcatc attggcatta ggagctacaa aatttcaaac tttatataag
     2581 gtagtacttc caagtgcaat accaggaatt ttatctggag taatcttatc agttggtcgt
     2641 ataattggag aatcagctgc aatattactt acagcaggta ctgtagccaa gatgccaggt
     2701 ggaatatttg atagtgcaag aacattaact gtacactcat acttactgac taaagagagt
     2761 ggagatatag caacagcagc cagtatagga attgttttaa tagtaattgt attagcacta
     2821 aacatgctag caagatttgt tgctaagaaa ttaaataaag ctaattatta aatttaagag
     2881 gtgtgaataa tggaattaat cgataagata aaaatgagtg taaaagattt ggatttattt
     2941 tatggtgata agcaagcatt aaagaaaata aatatggata taaaagagaa taaggttact
     3001 gctttaatag gtccatctgg atgcggaaaa tcaactttta taagaacgtt aaatagaatg
     3061 aatgacttaa tcgaagatgt aacaattaaa ggaaacattt ctgttgatgg agaggacata
     3121 tatacctcag atgatgttat aaatcttcgt actaaagtag gaatggtatt tcaaaagcca
     3181 aatccatttc ctatgagtat atatgataat gtggcatatg gtcctcgtac acatggacta
     3241 agagataaga agcaattaga taaaattgta gaagaaagct taaaaggtgc agctatttgg
     3301 gatgaggtta aagacaggct taaatcatct gcactaggac tttctggtgg tcaacaacaa
     3361 cgtatatgta tagcaagagc aattgctatg agaccagaag ttattcttat ggatgaacct
     3421 acatctgctt tagacccaat ttcaacatta aaagtagagg aacttataga ggatttaaaa
     3481 aaagactaca caatagtcat agttacacat aatatgcaac aagctgctcg tatatcagat
     3541 gaaacagctt ttttcttaaa tggagaggtt atagaattta gcgatacaaa aactatgttt
     3601 accactcctg tagataaaag aacagaagac tatataacag gtagatttgg ttaaaatata
     3661 taactataaa ggagttagac aatggtcaat aatagcttag atataagtat tgatacttta
     3721 aaagaacaaa cagtgcttat gatggaaaaa tgtgaagaag caatagaaaa gtctgtgact
     3781 tgtatgatag agaaggattt agagggtgca agaaaagtag tagaagatga tgaagaaata
     3841 aataaattaa gagaagaaat aagagataag agtatagagc taatagtatt aaagcaacca
     3901 atggcaaggg acttaagatt tatttattca ttaggtaata tatctataga gctggaaaga
     3961 ataggagatt atgcagcaaa tatagctaga gaaatgttga agataggtgg agaggcttat
     4021 ataaaagagc taatagatat tcctaagatg gcaaaagaat gtaagtctat gatgtctcag
     4081 actagagaag ctttaatctt atttgatgca agtatagctt atgatgttgg aactaaagat
     4141 gatattgtag atggattgta tgaacaagta caaattgatt gtttaaaaat aatgcatgaa
     4201 aactcaaata ccatagacca aggggtaaaa cttctactta taggaagata ccttgaaaga
     4261 attggagacc atataacaaa tgtatgtgag aagataattt ttgcaattga gggtaaaatg
     4321 gttgagatag gataaaaaac tgctttaaag cagttttttt attgtctaaa ttaagaaaga
     4381 attgataaaa aaatatgatt aatgggtaaa tttaaaaaat tgtgatatac taggaacata
     4441 ttaaatatga ggatgcgtat tttatataag gtgcttttta ggaggtggaa ctttgaaact
     4501 tcaaaagatg ggtatgagga ctataaaaac aggaattagt gtcactttat gtatgattct
     4561 tggtgactat ttagtagaga atatgtttta ttctctggta gcatgtataa tttctgttca
     4621 agatacagta aaaggttctt taaagacggg aatcaataga gtggaaggta ctattttagg
     4681 tggtataata ggattcatat ttgccatcat taaagctgga gacccatttt tatgtggtct
     4741 aggagtaatg tgctcaatat atttatgcaa tctgtttaaa ataaagtcag tagtagttgc
     4801 ctgtgtaacc tttctggcta tacatctagg tgtaggaaat agtgaccctg tgtattattc
     4861 tttacatagg gtgttagata catctgtggg tgttttgttt ggagtacttg ttaattatta
     4921 tgttgctaga ccaaattatc taaatagtgt tatagatgag tttaaaaaga tagaagaact
     4981 ttcaatgttg cttattgaag ataaaattct tagaaaagaa aatttaaatg tagagaaatt
     5041 tgaagaagaa gtagaaaaat tagaagaaat atattcaaaa cttattgatg agttggatta
     5101 tagtttgagt gaaactaata tagaaaaaat tgagaatgcc ttaaggatat gtagagaaat
     5161 acattttcat atgcagtcta tagagttact tgaaaataaa ctttatttga aagagcatac
     5221 atataaatac cttaagaaaa catataatgt ggataagcta gactggaata tagatgaaga
     5281 aaaaagccct gtattcaact atcatctaat gaaaataatg attgaaatag agttgttgag
     5341 aaaactaaat aaatcatatt aataatagta gttaaataat aaataaaaaa tagtatcttt
     5401 gtaaatatta aacatatata agtttaattt atggaggtac tattttttat gaatactaga
     5461 aatgacaatt ctaaaatact agaaatatat aaaatgaagc tttttggcga acttgtaaaa
     5521 gcagtgtgga atgatgacat agaggatatt gaaaacttac ctaataaaat tttaaatgaa
     5581 aatttaaagg ataatttaaa taattatttt agtggaaaat ttgataaaga tactatggta
     5641 aatttaatta gggtaactat gggattggat gtgacagaag atacagataa aaatttaaaa
     5701 gagtcactac atgaagctgt aaatttagat gaagtcaaaa gaccaataat atctgtaata
     5761 tcagatgctt gcaaatattg tgatgaaaat aataaggaag atgagtcatg taagataaga
     5821 agtaagcata ttaattgtaa tgaggaagat gtatgtagtg cttgtggtga ttgtgtatca
     5881 agatgtaagt tgggtgcaat ttcagataaa atagaattta taccaatgat aaaattgtta
     5941 aaagatataa agagccctgt atatgcaata gttgcaccag cttttgtagg acagtttggg
     6001 aaagatgtaa gccctggtaa attaagaact gcattaaaaa agataggatt tgaagatatg
     6061 atagaagttg ctttggcagc agatatgctt actgcaaaag aagcatatga ttattatgag
     6121 catatgaaaa aggacgaaga aggatgcttt ataactagtt gttgctgtcc tatttgggtt
     6181 agtttgatac aaaatagttt tcctcaaata ttggagaatg tatcaccatc cgtttctcct
     6241 atgattgctt gtgggagagc tgtaaaaatt ttaaatccag atgctaaagt tgtattcata
     6301 ggtccttgta tggcaaaaaa gaaagaggca atgttagaag atataaaaga tgcagttgat
     6361 tttgtgctta catttaaaga gttgcaagaa atatttgatg cattagagtt aaatccagca
     6421 ataatggatg agagtaatag agtagaggcg tccctttcag gtagagttta tgctagaaca
     6481 ggaggtgtaa gtaaagcagt taagttatca gttagaagaa ttgacaaaaa tataaaattt
     6541 gaagaaaagg catttgaagg aacaaaagag tgcatggacg gtctaaagaa agttctaaat
     6601 aaagaaatag aagctacatt tatagaagga atggggtgtg taggaggctg tgtaggaggt
     6661 ccgaagcgta ttttaagtgt ggaagaaggt actaagaatg ttgatgaata tagtgaaagt
     6721 acgaatatgg aaactccatt tgataattta aatgtattac aatttttaac ttctttggga
     6781 atcaaaagag tagaatcttt aggagaaaaa gaagaagaaa aggttaaaaa aatatttagt
     6841 agagatataa aaagtaataa gaaagagaat aaatataaaa aataactttt taagtcttaa
     6901 acttatgctt ttataaaagg gagatatggg ggatgaaaat taaagataat aaggctgttt
     6961 ttcatgtatt tataaggata tttcttatag ctgttttaat tttaactgga acattattgg
     7021 aggaaaaaat taataatgtt ccagttgaaa atataagttc aaaaggtgaa aatacactgg
     7081 aactgctttc tcaaagtaat actttaggag aaatcatata caaagcatct caagaagaaa
     7141 caaaaggtcc aggggctact tctgaaaaag tagcatacat aacaatagat gatggtccat
     7201 caaaatatac aaatgcacta cttgatattt taaaagaaaa tgatgtcaaa gcgacatttt
     7261 tcatgcttaa tcagaatatg aaaaaccaca aggaagaagt aaggagagtc ttggaagaag
     7321 aaaactcaat aggttttcat agtgtaagtc atgatataca taagttatat aaaagcccag
     7381 aagtaacagt tggggaattt aatacatgca ataatactct acaagaaata actggtcaga
     7441 gttcaaaatt aataagatta ccatacggaa gtaaaccata tatgccagaa ggttcatata
     7501 ataaacttat ggcaaatgat tatttaattt gggactggaa tttggataca caggattgga
     7561 agtcttctac aagtcagata gtaagtaata tattatatta tggaagaaaa agagatgaat
     7621 tagtagtatt aattcatgag aaagagcaaa gtttaaatgc tttaaataat attataagaa
     7681 tcttaaaaga gagaggatat acaatattgc caattacaga aaatataaca cctaaaaatt
     7741 tctggcaaga aaacttataa taaatttaaa tatagtaaaa gataaagtaa attatttata
     7801 aaataaaaca tataatataa aaaatacgaa taagaggtat actgtaagga taatataaaa
     7861 ttaatgagaa agcattaaaa ttaaaataaa ataatcttgc aattattgac attataagac
     7921 agaataactg taaaaacata ttttaaaata taacaactat ataaaagaga atagacataa
     7981 ttaagaaaat tcagaaaaaa taaaataaaa ataattgaca aagagaataa tatttgtata
     8041 taataatatg taatattaaa gactgagaag aagaggagta agtaaatact actaaaagag
     8101 aggaaaattc actggctgta agattttcta agtataagat ttactgaatg tagctttgga
     8161 gtttctaaac tgaactataa gtaagtttag acggttagaa ccgttaaatt ctttgagagt
     8221 caaagttgat aaaataacat taaccaataa tttaatgata tgttaatgta ttttaagctt
     8281 tggaattaag gtggtaacgc gagcttttcg tcctttttaa agaggatgaa gagctctttt
     8341 ttatttctaa agatatttaa aaaatttatt tataaaatac aggaggcagg acaatggaaa
     8401 atacgaattt atcaaaaact tataacccaa aagattttga ggctaggcta tataaaaaat
     8461 ggatggatga agggtatttt aaatctaaac caaatccaga taaaaaacca tttacaataa
     8521 tgatgccacc accaaatata acagggcaat tgcatatggg acacgctctt gaccatacac
     8581 ttcaagatat attaatcaga tggaaacgta tggatggata tgaagctttt tggcttccag
     8641 gaactgacca tgcttctata gcaacagaag ttaaagttgt tgaaagaata aaaaaacaag
     8701 aaggcaagac aaagtatgaa ataggtagag aagaattttt aaagagagcc tgggaatgga
     8761 aagatgaatt tggaggaaaa atatctaatc agcttaaaca actaggtgat tcttgtgatt
     8821 gggataaaga aagatttact atggatgaag ggtgtaatga agcagttata gaattttttg
     8881 taagcctata tgaaaaaggt cacatataca gaggaaatag aataataaac tggtgcccag
     8941 attgcaaaac tactttatca gatgcagaag ttgaacatga agaacacgac ggaaactttt
     9001 atcatataaa gtacccacta aaagatagtg aagacttttt agaaatagct acaactagac
     9061 ctgagacaat gataggagat actggtatag cagtaaatcc agaagatgat agatataaac
     9121 atttaatagg aaaaacagca atacttccat tagtaggaag agaacttcca atagttgcag
     9181 atagttatgt tgatttagag tttggaactg gtgcagttaa gatgactcca gcacatgacc
     9241 ctaatgattt tgaagtagga ttaagacata atcttgagca gttaaatact atgaatgaag
     9301 atggaactat gaatgaagtt tgtggaaaat atgaaggtat ggatagattt gagtgtagaa
     9361 aagctatcgt agcagactta aaagaacaag gttacctaat taagataaaa gagcataatc
     9421 ataatgtagg aacttgttat agatgccata cagtagttga gcctagatta tcagagcaat
     9481 ggtttgttaa gatggaagaa cttgcaaaac cagctataga tattcttaaa aaaggagaat
     9541 tagaatttgt tccagataaa tttgataaaa cttatttaca atggctagaa aatataagag
     9601 attggtgtat atcaagacaa ttatggtggg gtcatcaaat accagcttat tattgtcaag
     9661 agtgtggaga aatagtagtt gctagaaaaa tgccagataa gtgtcctaaa tgtggaagca
     9721 ctcattttaa acaagatgaa gatgccttag atacttggtt cagttctgca ttatggcctt
     9781 tctctactct aggatggcca aataagactg aagctttaga ttattattat ccaacaagtg
     9841 tacttgttac aggatacgat ataatattct tctgggtagt tagaatggca tttgcaggta
     9901 tgttctgtat gaatgaaaag ccatttgacc atgttttggt tcatggatta gtaagagatt
     9961 ctcaaggtag aaaaatgagt aaatctttag gaaatggtat cgacccattg gagataatcg
    10021 agcaatatgg agctgatgcc ctaagattta cattaacaac tggaaattcc ccaggaaatg
    10081 atatgagatt ctatatggaa agagtagaat ttgctagaaa ctttgcaaat aagttgtgga
    10141 atgcatcaag atttgtattt atgaatattg atgaagatat aattaaaaac atgactagag
    10201 aaagtgttaa agaggactta actctagctg ataaatggat aatatcaaga gcaaataata
    10261 ttgtaaaaga agcaactaat aacatggata agtttgattt aggaatagca cttcaaaaga
    10321 tatacgattt tacttggtca gaatactgtg actggtatat tgaaatggtt aaacctagat
    10381 tatatggaga agatgcaaat gctaaatctg cagcattata tacattaact tatgttcttg
    10441 aaaaaatatt aaaattatta catccataca tgccatttat aacagaggaa atatatactc
    10501 atcttcctac tgttgaagga tgtataatag tatctgaatg gccaaaatat aatgaagaag
    10561 ataacatggc tgaagaagaa gatatgatga acttattgat ggaaggtata agaagtataa
    10621 gaaatgtgag agcagaaatg aatgtaccac cttctaagaa agctaaattg ataataatcc
    10681 caagtgaaga aaaaatagaa gctattgagc ttggtaaaga ctattttata actttagcat
    10741 ctgcttcaaa tgtagagata gcaaaagata aatctaatgt tccagaagat gcagttggag
    10801 tagttattga tggtgttgaa atatttatac ctcttaatga attagttgat tttgaaaaag
    10861 aaattgagag attatctaaa gaaaagaaaa agttagaagg cgaaataaag agagttaatg
    10921 gaaagcttgc aaatcaaggt ttcttagcaa aagctcctga aagtttaatt gaagaagaaa
    10981 aagcaaaaaa agaaaaattt gaagagatga ttaaatctgt tgaggaaaga ttaacaaatt
    11041 tagaatctaa aataaaataa atataagaat tagtaaaaac atacaaaaag tatatattct
    11101 atactttttg tatgtttttc tttatatata tacaaatatg atgttataat tctttacaga
    11161 tgtgttatat ttttatttta tgttgtgaat atatgaattt tatgtcttaa aatttataag
    11221 caataaaaat ttgatatatt atgatgttta atatagggta ataaatacat attatattta
    11281 ttttactata tttttttaca taatatatct agaaaagtat aggaatttat cgtaatttaa
    11341 gtttaaatat taaagagaat ttctataagt agtttaatcg acaatttaaa tttataaaga
    11401 aatttaaatt tgaaagctag tgagtacagt ttggaaattg aaataaagta aactaaatga
    11461 tattttagat ttggaggtga tattatgttc agggtagtta tatgtgatga cgaaaaaata
    11521 caaagaagca tactaaaaga gtttacagaa aaacttttgt ctgaaagatg tctaaattat
    11581 caaatactgg aattttcctg tggagaagat ttaatatcca aatacccaga aaaaattgat
    11641 attatatttt tagatatcca aatgaaagat atcaatggaa ttgaggtggc taaaaaaata
    11701 agaaagtttg atgaaaaagt agaaattata tttacaacgg ctttttcaga gtatgccccc
    11761 caaggttatg aggttcgtgc ttatagatat ttagtaaagc ctatagagta tagtaacttt
    11821 gcaatgggtg taaatctttg tattgataac cttcaaagaa agaaggagcg ttatatagtt
    11881 ttaaatagta aaaaaggatt taatagaata ctgatagatt ctattttata tgttgaaact
    11941 gtaaagagag atttagtcgt acatacaata ggtagagatt ataaagctaa tatgagcatg
    12001 aaacaagcag aaaaattact gtgtgaaaat ggctttttta gatgtcatac aagttttatt
    12061 gttaatttaa gaagaataga agatcttagg gataatatga ttactattaa tgaacaattt
    12121 atacctataa gtaagtatag acttaaagat ttaaaagtag cattaacaag cttgttatgt
    12181 gatataatgt attaatttta aaaaggtaat tgaaaatatc gtaaaaaaga tttaatgtca
    12241 tcacagggct attgattgaa actgtcttaa tatataaaat gttatttata ttaagacagt
    12301 tttattatgc aaaatagcag tttatagatt tttaatatgg tttaacatgt atatgtagag
    12361 gttccattat agtagcatga ttattaatta gtagcttgat tatcaatata ctattattga
    12421 tttttatatg cattatatgt atttttagaa tatgattacc tttttaaaat aatgattatt
    12481 tataaaactc tatagatatt tgtttcattt agctacgcat actttaatta attatattaa
    12541 tatttaatgg agtacaatat aaatattaaa gcgacatctt atagtttatt gaaactatag
    12601 taatgaatta ataaatagtt taattctatg aaaagatttc cttttatgca atttatttat
    12661 tgaaatatga tataatatat aaaggtgtaa gtattagttg ttaaaataat atttatatta
    12721 gtttttatac atacttggta taagtttttc atatattgat taaaattgat gttgatttat
    12781 tatttttagt attttttcac cttttgattc atactttgta gaatggtgta ttttctaaaa
    12841 ctgattataa gacaagttca ttcaaattag catttttata tcatataaat aattgttccc
    12901 cctaaataag atttagatgt atagtattaa aatcaaaaag tataaaataa aattgatgct
    12961 taatcataga taaatattaa taaaatatac aaggggattg tctaataaaa agataatctc
    13021 cttttttaca aataattcta aattgtgata taaatctaaa aattttatct taacatttaa
    13081 ccatttaatg ataataattg atataataaa tataaattaa atatatggtg tacttatttt
    13141 atgtttttag caagaaatat agcatttaaa agataaattg tgcaacttaa atcaaagttt
    13201 aagatgaact attaacatag atatattaaa aacttttgta atggagaata tatgtgatat
    13261 gaataataaa gttaaggttg cagtattaga tacaggaata gacaaagaac atgattactt
    13321 aaaagataat ttagttggag gaattgcttt tgaatgtatg catgattata tctttatatc
    13381 agataaattt gatgatgaag atggtcatgg aactgcttgt gcatcaataa taaagaaaga
    13441 gtatgaagat gtagagttat ttgtaataaa aattttgaga aaagatggta ttacaaatat
    13501 aaaagttctt gaagaagcat taagatacct tttagacact aacataagat taattaattt
    13561 aagtttatca gtcataggag tagaaagtgt taagggctta tttgaagttt gctatgaatt
    13621 gtttagaaaa ggaaaaataa tagtatgttc actcgctaat gattttgact taagttatcc
    13681 agctatgttt aacaatgtta taggtgtaag aggatttact ttagatggag atgattcatt
    13741 ttggtacaac aaaaaatatg atgttcaatg tgttatggat agcaattcat atataagttg
    13801 tgatataaat aattcctata gattaccacc aaaatgtaat agttatttat cagcaaagct
    13861 tactggtaaa atagctaaga tattatcaga aaaaccaggc ataacaatat ctgatttaaa
    13921 tgataagctt gaatcattag caactagaaa tcattgggat agttgtgatt ttgatgagtg
    13981 tagtagaatt gtaaacttta aattggattt gtatgacaaa gaaaatgctc tttttatgaa
    14041 agttgctgac gttgttaggg attgcttaga tattgaagag aataatgaaa aactctttaa
    14101 gggtagcctt tttaataagg agataggctt ggtttatgat aattgtttta atctgttgaa
    14161 aaagctagag catagatttg acataaagtt taattatatg gacatctcaa aatatgactt
    14221 agtttcaata tatacactga ctgaattagt ggaaagatat aaaaacttat aaataaagat
    14281 ttgtagctaa atttaatgta gaaggtatta aattatatgt attctttgtc ggtagattaa
    14341 aagtaaaaaa tatactataa ttagatagca taagagaaaa tgccaataca gggggagtta
    14401 gataatgaaa tatgaagaag cattagagta catatcacaa actaataaat tcggtataag
    14461 attaggatta gaaaatatcg gaaagttatt agaattatta ggaaatccac aagaaacttt
    14521 gaatataata catgtagctg gaactaatgg aaaaggttct gtgtgttctt ttgtttctaa
    14581 tatactaaga gagtgtggat ataaagttgg tttatataca tctccatatt tagaaacttt
    14641 tactgagcgt ataagagtaa atggacaaaa cataccacag gatgatgttg ctagaataat
    14701 tgagttaata aaagaaaaaa tagagattat ggtaaaagaa ggctatgcat atccgacaga
    14761 atttgaagtg gttactgcaa tggcatttta ttactattca gaacaaaagg tagactttgt
    14821 ggcattagaa gttggtttag gtggcagata tgatgctaca aatataataa caaaatcact
    14881 tgtaagtgtg atagtatcta taagtttgga ccatacaggt atacttggag atacaataga
    14941 aaaaatagcg tacgaaaagg ctggaataat aaaggaaaat ggagtagtac tagtatatga
    15001 ccagactgat gaagcaaagg atgttataaa gtcagtttgt aaagagaaaa aagctaaata
    15061 tatagaagtt gattttgatg atataaacat aaaaaaatca gatataaatt ctcaaatata
    15121 cgattgtact gtaatgaaag aaacttatag agaccttgaa ataaaattga taggcgaaca
    15181 tcaaataaac aattctatct tggcaattag tgtaataaaa tatctaaaag acataaataa
    15241 attagcaaat ataaatgaag aatctataag aaaaggactt ataaatacta aatggccagg
    15301 aagaatagaa aagataaagg aaaatccaat ttttataata gatggtgcac ataatgaaga
    15361 tggagcaaaa tctttggcaa aagcacttga taagaatttt aaaggtagaa aattaacctt
    15421 attaataggt atgttagaag ataaagatat tgatagtgtt ttagagatat tgttgtcaca
    15481 ttttaataag gtaataacaa caacaccaaa taacccaagg gccataaatt cagatatatt
    15541 aagagaaaaa gtattaaaat atgtagatga tgtaacatca aagcatgaga tagaggatgc
    15601 agtaaattat acattagaaa catcaagtga ggatgatatt ataataagtg caggttcatt
    15661 atatatgatt ggtacagtga gaactttagt aaagaaatta taattttata aaataagtat
    15721 acaaataaaa atataaaaaa gagttgtcta aaaaatggac aactcttttt atataaaata
    15781 agtttttaat aattttactg atgtttatat aagtaattat atagattgac gtatagcttt
    15841 agataattgg tctgggcaag aagtaccttt tccaccacag tcaataccat ttaatttatc
    15901 agcaacttca agagcatttt ggccaattat taagcttcta agtcctgata aattaccatt
    15961 acatcctcct ataaactcag catcaacaat cacattattt tcatcaactt caaaaatcat
    16021 ttctctacaa catacaccac ttggattaaa tgttactttc attaaaaaga cctccattaa
    16081 atattatttc tttttttaac attaataata ataccaaata tatgcgtaat aatgcaacta
    16141 taaagcataa tacaagctaa tgaaataata tattattgta gtatatgtat tgtagagagg
    16201 aggggttata tgaaaatcta tatttctaac tacttatcaa agagtattag catagttgat
    16261 tattctacac ttgaactaga aaaagaaata gtattagaag ataatatata tccacaccat
    16321 ttttgcatag aaaaagaaaa aaatttaata tacataccta gttcaagtaa tgggatactc
    16381 tatgtcttag atttaagtaa tgataaaata attgatactg tctctatagg aggaagtctt
    16441 agtcaagttg tacttagcga taatgaattg tttgtggcaa atgaagattc taatagtata
    16501 tatgtactag ataaaaacac attaaatcca ataggaatta ttggagttga taatatgcca
    16561 catggatttg actttgatag agaaagcaaa aagttatatg taccgtgtat aaactcgata
    16621 gtatgtatag atacaattaa taaaaatata caaaagaaaa taaatatgga ctttagagct
    16681 tggcatatag aacttgataa acaaaagaaa gaaatgtata tatcaacact tgatggaaag
    16741 cttataataa tagatgaagt aagcatggat ataaaaaagg tattatatga atttttatta
    16801 ccagtagaaa taagatttaa ttatagtggc aaaaaagttt atgttgctga tttgggttat
    16861 aataatgtaa gaattttaga ttatacaacg agtagataca ttggaaatat tgaaataaat
    16921 gggattcccc aaggattaga aatatctaaa gatgaaaagt tactatttgt atcagataca
    16981 caagaaaatt cagtaaaagt ttatgaaact gcaaataaca aattaataaa agaaatcaag
    17041 gtaggaaaag agcctacaac tataatttgt ttgtaggctt taatgtatgt ctcttataag
    17101 taaatcgata acttcggcat acatataaga tgcattattt ttccagttat tgcaaataag
    17161 ttttgcttgt ttctctgatg aaacatttag atttaaatct attaagttag actgattttc
    17221 tatgactcta aggttgacaa taaattcatt atcactttgt tttacaaaac tagactttac
    17281 ttgagtatct gctagtagat tttctttgtt agaatctata tacttgtcta ttttttcagt
    17341 aacactagta ggtattcgat taaagaagta ttctagactt tctacgcctc tttgagtaag
    17401 agcataatat tctctgtcag agtctttata tgtagtcaaa aacttagatt ccataagctg
    17461 agataaaagc tgttgtaatg aaaaataatt catcatctca gtctctaata ctacttgagt
    17521 tatttgagaa ttagttaaat ccattttaat tttttctaat atatataaaa ttaaaagttt
    17581 gtgataggct aattcttcag acgagttttc aaacataaat atcatcctcc gtcaaactat
    17641 ttctatatat aatatattaa actaatttgt acaaaattaa aagaacaatt tgtattgtat
    17701 tattaatctt taataattca tataaaaaca attttataaa taaatataga aaaacagggc
    17761 tgctaattag cagccctgtt gatacccagg tgtcaaaatt tactatttat tttccagcca
    17821 tttgtctttc agccatttca actaatttct tagtcatata tccaccaaca tatccatttt
    17881 ctctagctgt taagttacct ttgtctatgt tttcatagtt agataaacct atttcgttag
    17941 ctatttctaa tttcatttgg tttaaagcag cttttgcttc tggaactact gttctgtttg
    18001 aatttgacat agtaaatttc ctcctcaaat aattagttta tgatgtctaa caacactttt
    18061 atttatgtga tgttaatact aatttctcca aaataaaaat aatatataca gaaaaataaa
    18121 ggtaaaaatg taaaaaatat aaaaaaatta aataaatgag tattttagag agtttaatta
    18181 ggtcaatata ggttttattt ttttagttat tgtcttataa attaaatatt acagtacttt
    18241 tttgagctga aaaaaaataa attttaaata tagaagaaat tatttcaaag ggggaatagt
    18301 atgaaaagag aagttaaaag gactaaagct ttgatatata gtgttttatt tttttcatta
    18361 ttattagtgt taatatttgt ttttgtttat ggaataaaat acatatgttc taaatctgac
    18421 aattcaaaaa tgcctatata taaagttgat acaaatgaga aaaaaatagc tttgagtttt
    18481 gatgtagcat ggggaactga taatatggat gatattttaa aaattttaga taaacataat
    18541 gtaaaagcta ccttcttttt agttggtagt tgggtggatg ataatgaaga aattgtaaaa
    18601 gctatagatg aaaaaggaca tgaaattgga aatcattcaa atactcatgc caatttgaag
    18661 gaaatatcaa aagaagacat aacaaaagag atagaaacta catcagaaaa aatatataat
    18721 ataacaggaa aaaggactaa tttatttaga cctccttttg gggacgtaaa caataaagct
    18781 atggacattt gtagtgattt aggttataaa gtaattaagt gggatgtaga ttctatagac
    18841 tggaaggagc ttggaccaaa tcatgtaatt gaaaaagtaa taaaagaatc tcaacctggt
    18901 tcaatagttt tattccatgc taatataaat gatgtagata actatttgga tactataata
    18961 agtcgactaa aaaaagatgg atacagtcta gtcaaaatat ctgatttgtt gtataaagat
    19021 aattatgtag ttgattccaa tggagtgcaa aaaactaaga attaataagt aataaatgta
    19081 tattttaagt aaagttgtga taaattatat agtatatgtt agaaaagtgt cgataaaaag
    19141 acggtgtcta ttttttgaca ctttttatac atgtatgcaa tatcaataat tatagattaa
    19201 attgattaaa aaagtgtcta ataattgact tttttttgat gggtttaaaa atttagaaga
    19261 attaatgaat gctgtaagac agtatttcca aagggtataa gtttgtttaa aagttggcat
    19321 agaaattgct ttgttaataa gcgatatgtt ctatagaaat aaacaatatg ttaagacctt
    19381 ataatagaaa aatagcatta acattatttg aacagcttat aaaaaaatta atatacttaa
    19441 gggggcgtac tagttgaaca aactatattc tattttatta aaacaacacg ttggtggtcc
    19501 agataagcca gtagtaagtg ttggagatgt agtaaaaaaa ggaactctaa tcgcagaacc
    19561 aactggatta ggggcaaata tttatgccag tgttagtgga aaaataagtg aaataaatga
    19621 ccaagcgata gtaattgaag ctgatgaagt acaagaagat acttttgaac cattaaaagg
    19681 agaaggtata cttgacttaa ttaaagaagc tggagtagta ggaatgggtg gagcaggatt
    19741 ccctactcat gtaaaattaa acatagattt aaatggtgga acaatattag caaatgcagc
    19801 tgaatgtgaa cctttattag ctcataatat aaaagaaata gaagaaagac cagaaatagt
    19861 ttatcaaggt ataaaatatg ctatggaagt tactaatgct ggaaaaggta tgctagcaat
    19921 aaaaagtaag catccaaaag caatagaagc tttcaaaaaa gtaataaagc caggagacaa
    19981 catagaagtt gcagaactag ttgatatgta cccaatggga gaagagagag caatagtaag
    20041 agacgttcta ggaaaattac ttgagccaac tcaattacct tcagaggcta atgcagtagt
    20101 aataaacgta gaaacactaa ctagaatagt agaggctgtt gagcaaaaaa gaccagttat
    20161 atctaaaaat ataactgtag ttggtcaatt aaacagtgga aaagaatcta tagtgtttga
    20221 agatgtgcca attggaacaa ctgtcggaga attaattgaa agagctggtg gaataaaagg
    20281 tgaatatggt gaaataatcc taggaggacc tttcactggt aaagctacta ctttagatgc
    20341 tccaataact aaaactagtg gtggtataat agttactatg ccatttgtta atgaaaagag
    20401 aaaaatgggt cttttagttt gtgcatgtgg acctaatgaa gaaagaatga gagatatagc
    20461 aactaaaatg ggagttactg atatagtatc agttcaaaaa tgtaaacaag ctcaagaaat
    20521 taaaggtgca ttaaaatgtg aaaatccagg acactgtcca ggacaagctc aaaaatgtat
    20581 tgaatttaag aaagctggag cagaagttat attaatagga aactgtactg actgtagtaa
    20641 cacagtaatg ggttctgcac caaaattaaa attaggtgta tatcatatta ctgaccatgt
    20701 aatgagaaca gttaatcacc cattaataag aagaataaaa ggtgacgtaa gattaaaaat
    20761 aaaataatag ataaatagaa gttagacatc tttagaagta aaacttaaaa gttacttcta
    20821 aggatgtttt ttaatgtatt ttgagggcaa tatatatatt gtaaaataaa tggaaaaaat
    20881 agacaaaata tgctagatat tgtataatga taataatagc tattacaatt aatattggac
    20941 aaaaataatg atactcaagt atgtggtttg tattaatatg catattatat taagtcaact
    21001 atccgataga gtaaaaggtt tttgtgatat ttgaagatac tctatagtat cttttttatt
    21061 ataaaaacta atttttgtct tttattagat aagtatctag gatactaatt tatattttat
    21121 tgagttgtta aaaaagtgca cttaaaaagt taaaaaagaa aaattaaaaa acctatttat
    21181 agaaactgtg aagtatatct taaacctggg cacttaaaag atatatggag ttagtagtgc
    21241 aacctgctat aaatataaat aggagtaact tttaattgtc aaaaatatat aaaataaata
    21301 cataaataag taattaatag aagatagata taaatatatt tttgaaatgc tccctgcatt
    21361 cataacgagt gtagagtggc agatatctgc ccaaaactcc tttaattgct ggaagttcct
    21421 aaagctaact aaaccacaac ataatcatga aataaggata agtgtgatag agtgtgcatt
    21481 taataagcac ttgaggttac gaaagtagaa aaaattagtt agatagcata aggttaaatc
    21541 ctaagtgcct tgaaaatgga taatcagcag gtaagcttcg aaaagaagaa acttcaacga
    21601 ctagagagaa atctcgtacc tacaagtgtg gggaaatggg gagtacctaa tttatggtta
    21661 ggtaatgata tagtctgtgc ttaatagaaa tattaagaag ttcataggag aactggttag
    21721 gagtaacgac cctaattgaa cacactaaag atgtattatt gaataagatt catataatat
    21781 ttaataattt taattatatt aagtgaatac aatatatgtt tttagtatca ggagaatttt
    21841 gaaaacaaaa attaaaaaat caagtataat cagtttagta attgctttta gtatggtgtt
    21901 tactgcattt acaccaatag tatcttatgc tgacgaagtg actagcaatg atacaatact
    21961 taatggagaa gaacaatcaa atggtcagac accagatgta gagaaaccat cagacggtca
    22021 ggtaccagat ggggagaaac catcagacag tcaagtacca gatggggaga aaccatcaga
    22081 cggtcaggta ccagatgggg agaaaccatc agatggtcag ataccagatg gggagaaacc
    22141 atcagatggt cagataccag atggagagaa accatcagat ggtcagatac cagatggaga
    22201 gaaaccatca gatggtcaga taccagatgg ggagaaacca tcagatggtc agatgccaga
    22261 tggagagaag acatcagata gtcagacgcc agatgtagag aaaccatcag atggtcagat
    22321 gccagatggg gagaaaccat tagatgagca aactccagaa gaagaaaaac cattggaaga
    22381 agaaatagtt atagaggaaa tgagtttaaa acaagatatt gataaaattc ttgatatgac
    22441 tttatctcaa ataaataaaa tagtatataa cttttgggaa gatgaagaag atgtaaaggc
    22501 agatgaacaa tcagaaatta accaagtttt tacttcagaa gactcattta ttagcttatg
    22561 gtatgacaaa aaagcaaaag taaaaaattc ttgtttacta aaagaaatag atggttcaga
    22621 tagaccttat catgatttaa gatttgatga tattacaaag actttaactt ttgactatgt
    22681 aataaagggt cttgtaggag caagctcaaa agacgacaaa tatgtaatag aaggtgaaga
    22741 tggagagcaa actgcatttt gttacaataa tcatttaaga ccaccaagta gtaatggaaa
    22801 gagtccatat ttaccagcag aagattttaa tggtcaagaa aaccaaaatg aagaagcagt
    22861 taaatctata ctatatgcag gttctgaatt tgatggattt ggatataagc aacaatttaa
    22921 tttaggtgga gaagaaaatg aattgatgac ttactcagct actcaaagtg caatttggat
    22981 tattcttgga caaatggatg aacaagaaag acttaagcag tatcaaggtt ctataaacct
    23041 ttgtgataaa cttatagaaa gagcaaaaac tgaagaggaa agagctgagt atcagaagaa
    23101 gaaagaagta gctataaata taaaagctta tttagaagca ttgttaaaag caggtcgtga
    23161 agagttaaag ccaaatgata caggaaaacc tagtttgagt aatggtttaa ctaagattaa
    23221 ctttgaaaaa aatgaagatg gtacttatga aacagaagct gtagccttag taggttatag
    23281 tggtgtagta aagttaagac taccagatgg agtaactgct tatgatggag atggtaatat
    23341 aataggtaca ggtgaagtag aaatttcaac acaacagaaa tttaaactta agagtgttgt
    23401 aaaaccagat gccaaagcta atatttctgc tgtatcttat gattatattt ttccaaaagc
    23461 tattcaatat tataaggcag tgcttgattt aggacaaaaa gaccattcat cttcattacc
    23521 atctagtaag caaaatttat taagttatac aatagagaaa aaaaatggtc aagaagttaa
    23581 ctttaatata ggtctaccaa cagatgatgt tgtaaatcca ccagtgccac caacagatga
    23641 tacaaatgga cataagccaa aaccatcacc accaatagat gatacagtaa taaatccacc
    23701 agtaccacca atggatgata caataataaa tccaccagta ccaccaacgg aggatgcagt
    23761 gttaaatcca ccagtgccac caacggagga tgcagtgcta aatccaccag tgccaccaac
    23821 agaggataca gtgttaaatc caccagtacc atcagtaagt gatacagtgg aaaaaactcc
    23881 agaactatca agagatgata caataataaa atcaccaaaa acaggtgatg aaactcagct
    23941 aatgtcatat gtatttatta gtgtcattgc aatttgtgga ttagcgtatc aatgtaaaat
    24001 aaaaagaaat taatctagat tattattaag tttaaaataa aaagtctcaa attgatttat
    24061 aagtcatttt ggggcttttt tatgtaaata taatatgcaa atatagtttg tttaaaaata
    24121 tatattttaa ttatattctt aaatttatga ttggatacag gcattcatta attgtttgat
    24181 gaatagaaaa atgttttgaa ggtgaaaata gtattgaaaa aataatatac taagggtata
    24241 attcatttga tttcatttgt ataaatttaa ttataaattt taaagtgatt
//
LOCUS       DAEHWO010000056        24096 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEHWO010000056 DAEHWO010000000
VERSION     DAEHWO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24096
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.056"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     regulatory      224..325
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            398..1741
                     /locus_tag="KNP54_002671"
     CDS             398..1741
                     /locus_tag="KNP54_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBF0893546.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            1920..3284
                     /locus_tag="KNP54_002672"
     CDS             1920..3284
                     /locus_tag="KNP54_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0893547.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(3462..5327)
                     /locus_tag="KNP54_002673"
     CDS             complement(3462..5327)
                     /locus_tag="KNP54_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBF0893548.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(5563..6780)
                     /locus_tag="KNP54_002674"
     CDS             complement(5563..6780)
                     /locus_tag="KNP54_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0893549.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(6980..7843)
                     /gene="aroE"
                     /locus_tag="KNP54_002675"
     CDS             complement(6980..7843)
                     /gene="aroE"
                     /locus_tag="KNP54_002675"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBF0893550.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(7925..9847)
                     /locus_tag="KNP54_002676"
     CDS             complement(7925..9847)
                     /locus_tag="KNP54_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBF0893551.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(9911..10759)
                     /locus_tag="KNP54_002677"
     CDS             complement(9911..10759)
                     /locus_tag="KNP54_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBF0893552.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            11172..12053
                     /locus_tag="KNP54_002678"
     CDS             11172..12053
                     /locus_tag="KNP54_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0893553.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(12261..13124)
                     /locus_tag="KNP54_002679"
     CDS             complement(12261..13124)
                     /locus_tag="KNP54_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBF0893554.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(13279..15213)
                     /locus_tag="KNP54_002680"
     CDS             complement(13279..15213)
                     /locus_tag="KNP54_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBF0893555.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(15325..16338)
                     /gene="galE"
                     /locus_tag="KNP54_002681"
     CDS             complement(15325..16338)
                     /gene="galE"
                     /locus_tag="KNP54_002681"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBF0893556.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(16362..17231)
                     /gene="galU"
                     /locus_tag="KNP54_002682"
     CDS             complement(16362..17231)
                     /gene="galU"
                     /locus_tag="KNP54_002682"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBF0893557.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(17429..17749)
                     /locus_tag="KNP54_002683"
     CDS             complement(17429..17749)
                     /locus_tag="KNP54_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893558.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(17739..19730)
                     /locus_tag="KNP54_002684"
     CDS             complement(17739..19730)
                     /locus_tag="KNP54_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893559.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(19853..22396)
                     /locus_tag="KNP54_002685"
     CDS             complement(19853..22396)
                     /locus_tag="KNP54_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBF0893560.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(22674..23008)
                     /gene="rnpB"
                     /locus_tag="KNP54_002686"
     ncRNA           complement(22674..23008)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KNP54_002686"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            23140..23817
                     /gene="srtB"
                     /locus_tag="KNP54_002687"
     CDS             23140..23817
                     /gene="srtB"
                     /locus_tag="KNP54_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBF0893561.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(23977..24051)
                     /locus_tag="KNP54_002688"
     tRNA            complement(23977..24051)
                     /locus_tag="KNP54_002688"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24017..24019),aa:Thr,seq:tgt)
BASE COUNT         7702 a         4164 c         2713 g         9517 t
ORIGIN      
        1 tattcagtac ttttataatt atatcacaaa ctcatttata ataaacttcc attaatagta
       61 taaaacaagt tagaataatt gacattatac tcatacatat tcaattattg gaaaaagtaa
      121 tttttttcaa taaataacct taatttttta taaaatcgac aaaaaaacga ataattttat
      181 tatatttatt gtaaataata caatattacg atataataca acagaaaaac aaatagaaaa
      241 tgttcatata atattagtaa tacggtctaa tagtttctac aaactcacct taaatgggtt
      301 ttctatgaat agaatgtcaa ctctgaatat atgttctatt ctatctatat gaatatatat
      361 ttttttgttt atatcttaaa gttttttgga ggtaaaaatg gtaccaaaca ctaacaatgt
      421 acaaccaggt ggaaataatt catcattaag ctttttagac aaaatgttta aatttagcga
      481 acgtggctct agccttaaaa cagaagtaat aggtggagtt actacattct taacaatggc
      541 atacatagtt ttcgtaaatc cagcaatatt atctgaagct ggaatggata aagccgccct
      601 tataacagtt accatactag ctacagccat tggtacactt atatttgcga ttttaggaaa
      661 tgcaccattt gctctagctc ctggtatggg attaaatgca tttttcacat actctttggt
      721 tataggtgca ggaatcccat ggcaaacagg tcttggggta gtttttctat ctggatgtgt
      781 cttctttaca ctcgcagtaa caggtcttcg aaagacaatt gcagacgcaa ttcctagaga
      841 attggcagta gcatcttcag caggtatagg tcttttcctt gcttttgttg gtttaaaaaa
      901 tatgggtgtt ataatagcta atccagatac tatagtttca cttgcagatt ttacaccaac
      961 agttttaata gccctttttg ctcttatctt aatggcaata ctagaatata aaaaagttaa
     1021 aggtggaata ttgataagta tagtagttgc aacaataata tctgttatat ttggatttgt
     1081 ggagttgcca acagcaataa tctcaacacc tcctagtata gcaccagttg cttttaaatt
     1141 agatattgta ggtgcattga aattctcatt aattggacct atattctctt tcatgtttat
     1201 agacatgttt gattcattag catttcttat tacttgttgt aaacaaatgg gtcttgaaga
     1261 tgagaatggt gaaataaaag atttaggaag aatgttatat gcagatgttt cttctacttt
     1321 aataggctca ttcttaggaa ctagtactgt tacaacattt ggagaatctg cttctggtat
     1381 tgcagcaggt gcaagaacag gacttgcttc aatagtaaca gcagcattat tcttagctac
     1441 acttatattt acaccattac ttggtatagt tcctacttac gctgcagctc ctgcacttgt
     1501 aatggttggt gtgtttatgt ttgaaagcat aaaacagatt gattttgctg atagcaaaat
     1561 agctgtacct gcttttgtta cagttttatt gatgccttta acttatagta taagtattgg
     1621 tttatgcttt ggatttattt catatataat aatgcatgta gtagctaaag aaactgataa
     1681 aatcagtatt acactttgga ttataggttt acttgcagtt gtaaacttag ttctaagtta
     1741 atatttttaa atagttctag gtcaatattt taaattatat agaataaaat cttatttatt
     1801 ttaaatttat aaatagcaaa atcactttat atgtaaattg attttgctat taactttgta
     1861 tagaaaattt attatcataa tatatagata taaaaatata tagaaaagga gtggtgttta
     1921 tgtcacaatt acttataaaa aatgcatatc taattactat gaatgcagat agagaggtat
     1981 atgaaaatgg aagcatactt attgaaaata atattataaa agaggttggt aagtttgata
     2041 ttaatattgt agataaagat gcagagatat atgatgctaa aggaaaaata ctaatgccag
     2101 ggctagtcaa tactcatgtt cacttatctc aacaattagg acgtggtctt gcagatgatg
     2161 ttgtactttt aacttggctt agagaaagaa tttggccata cgaaagtagc ttcaattatg
     2221 aagattcctt gatttcatct actgcatgtt gtgttgaatt gataaaatct ggtgtcacta
     2281 catttttaga atctggtggt caatatgtag atgctatggt tgaagctgtt gataaaactg
     2341 gacttagagc ctgtttagct aaatcagtta tggatacagg agatggtctt cctgaggcat
     2401 ggcaaaaaac tactgatgag gaaatcaaca ctcaattaga cttattccat aagtttaata
     2461 atacatctaa tgagagaatt aaaatatggt ttgcattaag aactattttt aatacaactg
     2521 aagaattact tgttagaact aaagaactag ctgataaata caatacaggt atacatatgc
     2581 atattgctga aatagctgat gaaatttcat ttgtaaagca aaacaatgga gttggaacag
     2641 ttgaatacct tgataaacta ggtgtattag gaccaaatct tttagctgct catacagttt
     2701 ggcttactca taaggaaatt gatttattta gattacatga tgtaaaagtt tctcatgacc
     2761 caggttcagc tatgaaagtg gttctagggt ttgcatcaat tcctgaaatg ttagaaaaag
     2821 gaatacctgt ttcaattggt actgatggag ctccttcaaa taatagaatg gaccttatga
     2881 gggacatgta tcttacatca ctaatacata aaggaagaac tttaaaccca actgtcgtac
     2941 cagctgaaga agtcttagaa atggctacta taaatggagc aaaatgtgct ttactagaaa
     3001 aagaaattgg tagtcttgaa gtaggaaaaa aagctgatat gattattcta aatccagata
     3061 caattcattg tttaccaatg cataatccaa ttggaaatat agtttattct atgactagtg
     3121 aaaatgtaga ctctactatt tgtgatggta aatggttgat gaaggaaaga aaagtattag
     3181 ttgtagatga atctgaatta ttaaataaag ttaaaaaaca agcttctaaa ataaaagata
     3241 aagcagaagt taaaattcca tctaaattta aaattataaa ataacataaa tttcaattgt
     3301 tttgtaaata tgaatatata aatatattta tatacatcat atatacaaaa caattgtttt
     3361 tttattttat attcattagc attgctcata aaatacacca taattccaga aaaaataacc
     3421 aatcagttag gattacatca tctaagcaat atataaacgt cttagtttat aagttttatt
     3481 ctactcttat ctaaaaccat ctttaaagag ttttcaactg tttcaattac atctttataa
     3541 ctcaagtaca catttgcgta gatacaatct tcatataaat tatattcagt tactctacaa
     3601 tacagcagtt ttcctccatc taataaattg ctcaaaatat agttttcttt tcttgggaca
     3661 tagcctatca catatccagt ttcaccaact attttaatag ctttttcatc atatagatta
     3721 tctttctctc tagttaaata gtatatctta cttttctcca attctttttc aagatattct
     3781 ctatttctaa accttgaacc agcaacagct attgaagtca aatagatatc cttaccatgt
     3841 tcatctactt ttattttttc aatatttaca aattcttttt ttaaattatt actttcatat
     3901 aatactcttc ttaattcatc cttcaatata acattttttt ctttttcata cgcttcttta
     3961 acaattttta attcttcaag agatagtttc tctctgtatc tttttaagat atttatggat
     4021 tcttttctta cttcatttat atttccaaat attcctttta aagatatatt ctttccttca
     4081 ggatatagtg atttacttcc tttaagcaca ataaaaaata acatatcatc ataatattct
     4141 tgagtcaatt tatctttttc tatatctttc atttttccaa ttaaatcatc tattttaaac
     4201 gtctcttcaa aaaaatttaa taattttaat ctagaacttg tcgttccctt tttagatata
     4261 tgccaatata cctcaaaatc tctaatatct ctatttagat atggcaacaa gtcatcaaaa
     4321 gataagttta catcataaat ttctgacatt tttataatat cttctgtttt tccactagca
     4381 tctcttaatg cttcaaaata tatatttttc catttttcac tgagcaagat accatttatt
     4441 tctttttcaa attcaatctt attgcactct atattttcat cttttaagac gtttatagct
     4501 attaggaaaa ttgaatataa actttcaaag ttagtcccat aatttactac agtaggtaaa
     4561 aatcgattca ctaattctaa tttattacct atatatttaa attctacact tagcaagtaa
     4621 ttgcatataa gacgtgctaa attatttatc ttttctttat ctaaatctcg tttttcaaga
     4681 tattcattca aatctacaat tgaaataata tagttcatca ataatcgttc gtactttgta
     4741 tccttataac catcttcaat tagataggaa tttattttag aatctaaatt ttccatatta
     4801 acaatagcaa atacttttat tgaacctgta gcctttttag ataaattaaa taaatatgta
     4861 ttgtaaaatt caagtttttt aatagtatta ctcagataaa atacgtattc tccagattta
     4921 gaaaatgtat ctacaacttc tcttaagttt tctacattta gatatttctc acttaaaact
     4981 aaccctagtt ttacatactc aactttttta ctcttatata ttaattcttt agttaattta
     5041 tataaccatt tctcatcaat aatcatttct tttaccaaag tatttatctt tttcataaaa
     5101 atttcgaaat aacaaattaa agacttagaa ttactaccct ccaataaata aatttcatta
     5161 gattcacttt tatacatatt taaaatttca tctactagat tatttgcaag ctctacttgt
     5221 tctcttaacg gtatactttc atatatacat aggtaattca tttcaaatga ttctttgtat
     5281 ccatcataac cattaaattc ctgcaatcgc ttaaaaacat tctccaccaa attatcctcc
     5341 tttacatgat gtaatttata ttgattatac tacttatttc atcaagttta catttatacg
     5401 caaaaaaata ttactagaaa ttgaaattct agtaatatcc ttattattaa ttatgtaaat
     5461 accctatctt ataactgtaa ataatatcct tattaatttt aattactttt aataaaaatc
     5521 tatcctagat ttagacttct ctatgcatat attatactaa tattagacat cataatcata
     5581 cactttttct ttttcatatc tcatgtttac aaacaatgca agtaaaattc caacaaatgt
     5641 tattgccaca ttaaacaata caacatattt tggtccatta actccccctg attttgtaat
     5701 aatacctgct atatttaaaa taacatagtt tgctatacta gatgcaatca taactataga
     5761 tgttattttt cctttattag ttggaaacat ttcatttgca gttgacgttg ttaactgaag
     5821 aacacctcct gctgctgaat aacctattac aaatccccct aacatacaaa tagttggagt
     5881 ttgaacaaaa tatacaacta atagcataag taaagctatt ataggatata taactaatat
     5941 tcttattggt ttaatatatt ttttaataag taaagaagtt attaatactg cacatattac
     6001 tcccattgag taaaaggatt gaatttttgt agggtcagcc atcccataca atttacccaa
     6061 ttcctgatta caatttaacc ataatacaaa tgtagatgta catgtaaatc caatacaaac
     6121 aagagctata cttgttggtg taaatttcat cttctctgat ttaactgttt tgcctttgtt
     6181 atcaataaca ttattagctg gtggaaatgg taacacagct atcaaaaagg catctactac
     6241 aataagaatc gctgttacta taaaaataac tttaaatgat attgaatttg ctgcaacaaa
     6301 tccaattata aaaggaagca aaaattgtgc taaagctatt gtaaatttag taaacatatt
     6361 tgctattgtt cctaaactag caaatatctc catacaagaa ggagttacac aggtatctaa
     6421 gaatgaattt gctgcccctc caattattgc aaatacatat gctatataaa aatttggtga
     6481 aaatacaatt ccaacaaaga aaattgcatg tagaaagttt cctataagac cacttacttt
     6541 tcttccatac ttatctgaaa taggtcctgc aaatggataa gatataagtc tccctaatcc
     6601 tagtgcagca ataacagcta aaacaatact tacatccaat gttccatctg ataatgtttt
     6661 agccccccac attgatgaaa attctggttt gtattgtcct aaaattgaaa ttccaatacc
     6721 aagtaaaaaa tatgaaaaat acaacgctat ggcagtagga taatattttt tattgttcat
     6781 aatttttctc ccattcttgt taatttatta acatttttgt gtacaataaa ctcatcccca
     6841 taatggattt aaagtatagt cagttaaagc ttcaaattta actggactat gaggcaaaac
     6901 ccactatgac aatttgtaat ttattattaa aaatattgaa atacgtatgt tttttcattg
     6961 tttaagatat tactcttatc tatttaaagc ataattcatt aacttcttct acaggcattt
     7021 ctaatccagt atatagatta aaagcttctg ctccttggta taataacatt cctaatccac
     7081 caatagcctt acatccatta gcttcagcat cttcaatcat ttttgttttc ttaggattat
     7141 aaacgacatc tgttactact aaatcttttc ttaaaacact agtatctttt atatttgttt
     7201 cattgtcata aggcttcata ccaataagag ttgcatttgt caatatatca cttgattgta
     7261 tctcctcata aagtttgttt gtatcttcta aatcatatag attaacaaca cattctggta
     7321 catctttttt tatattctca actgtttgct ctgctctttt ataaaaatca tccttaggat
     7381 taaagataga tatttctctt gctccatcta aagcacattg tacttgtata gcagttgctg
     7441 caccaccagc acccataatt gtaatctttt tacctttaac ttctacccca ttttctttta
     7501 aattacgaac atagcctact ccatctgtta tatgaccaac taactttcca ttgtcattta
     7561 caattgtatt acatgctcca attatacgag ctgctggaga aagttcatcc atatattctg
     7621 taacagcaga tttacatggc atagtaacat tggctccttt tatattaaaa gtttttattg
     7681 ctaaaagtgc ctcttttacc ttatctactg tgatatcaaa ggctaaatat ctataatcta
     7741 aatctaattt cttaaaacta taattataca tcactggtga tttagagtga ccaaccggtg
     7801 tacctattaa tgcaaataat cctgttctac ctgaaatttc cataactata atctcctctc
     7861 aatattatca ttttctttgc aaataaccta ttcagttatt tacaaagaaa aatttattta
     7921 ttatttatat atttaatgct acttcaaaag cttcttttgt tgcatctaat gccctacgag
     7981 cttttactgc atcaccaaca atataagttt cttttacaac ttcttttata acttcactta
     8041 atgggtcgta attacgagaa cccatagcaa gtactactga atcaaaacct tttaaatcat
     8101 gctctgtgcc atctgtaagt aaatagtcga caccatcatc ataaaattta gaaacttttg
     8161 caccagtaat ggtatgtata ttataatttt caaaatcatt cataaggaat ttacggtgtt
     8221 ctgaaattac atctgcacca acttcttctc taagctcaat aacagtaacc tcatgttctt
     8281 gttctccaag gaaggctgcc acttcacatc caaccattcc acctccaaca acaagtactt
     8341 ttttcccaca agatttttta ccatcaagaa ggtctacagc atgaattaat cctgaatcat
     8401 tgattcctgg tataggaagt acaagtggag ttgctccagt agctataata actacatcag
     8461 gtgatttctc ctttataagt tctactgtag cttctgtatt agtacatatt tttacaccat
     8521 attgattaca ttttgaaata taacttctaa ctaagttagt aatatctcct ttccctggag
     8581 gatatgcagc taaacgcatt tgcccaccaa gaacttcaga tttttcaact aaagttacat
     8641 tatgtcctct tttagcacat acccatgctg caagcatacc tccaacacct ccaccaacaa
     8701 caagaacttc tttgctaatt tcagctggct taagctctgc ttcatgtcct aatataggat
     8761 ttgcaagaca ggctataggt ttgccttgga acatatttgg tacacatcct tgtaagcatg
     8821 caatacatgg tatcatttcg tctagttttc catttttagc tttattaggc atttctgggt
     8881 cagccaagct ttgtctaccg aatgctacta aatcacatct tccttgtctg accattaact
     8941 cagcaaactg tggctctgta taacgtccaa ctgttattac tggtatacta acagcttttt
     9001 ttatttcagt aactaattct gcactgaatc cagcatgtaa agtcgtagga gcccacatat
     9061 attcatcatg tatatgtata ctacgtgaaa catgaagtcc atctattcca caatcttcta
     9121 gatatgctgc tattactgaa ctatcgtgta catcaattcc tcctggaaca tcatcagtgc
     9181 tgtttatacg acataatatt gctagagaat ttcctacttt tttacgtata ttttcaatga
     9241 taagacgagg taatctcatt ctattttcaa aacatccacc aaactcatct acacgcttat
     9301 ttgttctttg tgatataaaa ctactaacca gatatccatg agcgcagtga acttcaacag
     9361 catctgcacc agctttttgt gcacgtaatg cagcatctcc ataagattct ataagttcat
     9421 atatttcttc tgttgttatt gctagtggtg tattacgacc atttgatgca ggtattgcag
     9481 aagcagcttt taatggatgt cctgctactt tttcatttcc ttcagaacca gcatgttgta
     9541 attgtataga taccttcgaa cctgcatcat gacaagcatc tattacattt ttaaaactat
     9601 ctattgtgct atcatcatat aaacaaggct tacgaggacc tccttttgct tttttgtcta
     9661 caacactaga ttctatagtt attaatccaa aaccacctaa agcacgctca agataataag
     9721 ccttagaagt ttcacttaaa gtaccatctg tgtttgcaaa attgtttccc atagggggaa
     9781 ctacaaaacg atttggaact gtcattgaac caattcttat aggtgtaaac atagaactaa
     9841 tcttcataag gttttccttc ctttcaagtt ttatattata atactctgta tatttttata
     9901 ttatataagt ttattttgga gatacttcag accatgcttt atccaaaact tttttagttg
     9961 cattaaatac agtttcagca gcagtggata accctttaga tattagagaa tcagatatta
    10021 cttctgcccc tatgactctt ggtgatatat tgtgttcttt tattattttc acaaattcct
    10081 ctgtgtttcc atatccttca cctggagcca aacggtcatg tagtgattca tccctaagtt
    10141 tttcataagg agtttctaaa acatcacaca cttgaattga tactatctta tctgctggaa
    10201 caggtgcaag gtcctctgct gtctgctttg ctctagccca gtgccaagta tctaatataa
    10261 gcattgcatt ttcacgatta catcctttca caacacgcca tgcagtagcc aaatctggta
    10321 caccactata tggcataaac tcaagaccta taataagttc acctgctctg tcacataatt
    10381 ctcccaatgc agttataatt tgttcttctg gtatcatctc taataatcca caatttatat
    10441 gtttaacatt aaataagtga gccatatgat aaacattttg ctctttttct ctttgagctt
    10501 ccgttctatc ttcttctctt ccccattgag ttatatattc tacttctgta actttcatat
    10561 catattcatt aagaattgca atcatttctt catctgtaac acctgcattt tttgcatcaa
    10621 tataattttc agcacgcaat ccaataccat caaacccagc ttcttttgca atacgaactc
    10681 tatcacggaa tgaaacttct gttcccaatg tataagaact aattgtaatt ggaatattaa
    10741 gatttttttg attattcata gcttaaattt gcccccttta ttttctttat aattaatagt
    10801 atttttgatt ttatattttt atttatccta ctagtagtat tattttacct taaaaataaa
    10861 agtatttttt gatttctatt tatctagatt ttataaattt attgtatcac gagactttac
    10921 taataacaaa ttgataattt cctattaatt catagatttt gtttatagat tttatttata
    10981 agataattct tgtatttttc tattaggtcg tataaatata tttatcttat aattcagaca
    11041 aaaaacgata aattttttta aaagctttta ttcttactct ataatcatat ataataaaaa
    11101 tgtaaaaata tcttaaaggt taacttctac aaatatataa ataaaaatac ctatgaaagg
    11161 atgaacaaaa attgaattta tatcacttac gctattttgt tacattggca catttagaac
    11221 actatacaaa agcggcagaa aatttatcta taacacaacc aagcttaagt catgctattt
    11281 ctttactaga aaatgaactt ggggtggctc tatttgaaaa agaaggtaga aatatagtcc
    11341 ttactaagta tggaaaaata tttttaaaag atgtggaaaa atcattagaa attttagatt
    11401 caagtgtaaa atcattaaaa ataactggta ctggtgaagg acaaatagac ttagcttttc
    11461 ttagaacact tggtactgat tttatcccag acatagtgca caaattttta aaatctaatc
    11521 ctgctaaatc aatagatttt aaatttcata ctggtgtaac tactgacatt attcaaggtc
    11581 ttaaagaaag aaaatatgat attgcatttt gttcgaaact tgaaaaagaa aagggaattg
    11641 aatttatacc tgttgccaaa caagatttag tactaattgt accatatagt catccactag
    11701 ctgcaaagga tactatagat ttaaaagaaa ccatacctta tcctcaaata gtatttaatc
    11761 agagaagtgg tcttagatat ataattgatg atatgtttaa aaaaataaat caacagccta
    11821 atatagtcta tgaagtagag gaagaccaag taattgctgg attagttgca aaaaatttcg
    11881 gaattgctgt agtcccaaat atgaatatgc ttagctttac aaaagtaaaa gtaattcaga
    11941 ttattcaccc aagttgggaa agaaactttt acttagcatt tataaaagat agatatttgc
    12001 ctcctgcaat taaaaacttt aaaaactttg tcattaaaaa cgctcaatta taatttatta
    12061 ataaaggggt tatttttaaa tatcctcttt tattcttttt ataaaataaa aaaatctata
    12121 cttttaaaag tatagattcc taactgacag tcggcatccg agtctcagta attatcgtta
    12181 tacaacagca actggattca gttcctgaat aactaggtta cttacattat atcagatttt
    12241 ttaaaatttg tcaattgtat ctaacgcatt ttttcaagcc atggtccaac aggctctaca
    12301 ataggaactt ctttaaatcc ccaatttctt atatcattca cactcgttgg agtatatatt
    12361 ttgtttctga cagatttgaa tattttgttt ttttctccat attgcataca ctttggatta
    12421 gcttctatta accctcttct tgctctgcta agaggattac ataaaatatc tgctatttct
    12481 aaaccttctc tatagtcagc atcttctttt ttggcaatta taaaaccctt aaccttatct
    12541 cttaattctt catctatatc taagtatatt gttccattat taaatacatc aaaaaacgcc
    12601 ttttgtactt ttaagtttga gacatcatcc cttgactcta taactattcg tgcagattct
    12661 acagtttcat tatttacaaa tgaataaaaa ttctgaagaa catgtataaa agccacaaca
    12721 tacggttcct ttgaaggtgc ataatatttc tttaatctag ctttatctac tgttactgat
    12781 attatagtac actctaatct agatagaaat aaaggcaact catcatagaa taacttaatc
    12841 tgtgaatcat caaacttctc aaatgctctt gattttcttg atatatctgt caaatgtatt
    12901 cctatgttac tggttccaaa acaatactct ttaaatgcat ccatttcttt cctcaaagaa
    12961 catacataat cgccttgact tactgcatat ttatattcaa aaattactcc tgtcaatgta
    13021 aatgggtctt catgatttat atcagctctt ccactttcat caataaacat tatatatttt
    13081 ttctttataa tcttactcac cctcttaaca tatgatgata gcatctatat tcattttata
    13141 tgagttttaa aaatattcca agatttttat ataacttaaa cttaatttta tactaaaaaa
    13201 ttgagatgta aaacaatcaa gcttttattg attgaatttc acatctcaat tataattatt
    13261 tttcaatata tatttttact attttgcaag aatatccatt aatttatcca ttactatata
    13321 agatactccg cctcctattt gataaggagt ttcaactttt ttatttgcaa atactctttg
    13381 ttgctctgat gataatcctg aattatccat taaaactatt ggtgaatgta attttacagc
    13441 taatggtcca gctgataaag catctactaa agcatctgat ttactaacta atacagcctg
    13501 taaatcagta tctccataga atttttctat cactttggca ttagtatcta ctctactatc
    13561 tccatatatt ctatttcctg aaatatcttc agtagttata tcattcattt ttgctattac
    13621 tgaatcgtta attgcacttg gtccacctat aaagtatgca ttttctaatt ttctttctgt
    13681 tagccattta taagattctt ctgtaattcc atctttattg actaatatta taggttgttt
    13741 ttcttcccca gctttagaag ctacagataa agcatctgcc tccccatttc cagaaaccat
    13801 atatgcagtt tttatttctt ctcgatttcc aagttcttca gctattcttg tagcagtttg
    13861 atatctatct tgacctgcta ttctctttgt ttctgtgttg aaagtagttt ttatttcttg
    13921 ctctaattta gaacttattg cattttctcc acctatcaag attactgttt taggtgctaa
    13981 taacttcatt tcttcaacag tttcagttgg taaattagct gtattagtaa gtagtattgt
    14041 tgagtcatag ctacttgcta aaggagttgc tgttatacca tcagctattg cattaccatt
    14101 tactaatatt acagtatctg aactatcagc attccagttt ccaactgaac ttatcttttt
    14161 agctgtatca aatctatttg cacctataat tgtatcccat gtaggattta tagttccatc
    14221 ttcattaaaa gtataatctt tcccatctat tttttgagaa ccagttagca tctttccatc
    14281 tttgtctaaa tagtaagact taccatctat ttgttgccat cctgtctgca ttattcctgt
    14341 tttgtcaaag taatacttat taccatctat ttcttgccat cctgttactg ctaaaccatc
    14401 agatcctaga tagtatttct ttccattctt ttcttgccat cctgtttgca ttactccatc
    14461 tgagttaaag taataagttt ttccgtctat tactttccat ccagatactc ttgctccatc
    14521 agttcctaaa taatattttt tgttattaat tgttttccat cctgtttgca ttactcctga
    14581 agcatcaaag taatacattt ttccatttac ttttagccaa ctattctttt ggtatgttcc
    14641 atcagatttt acataatact tcttaccatt ttctgttttc catcctgttt gatttagatt
    14701 tatcttatat tttgccgcta tctttacata gctgtcgtta ctataatcta taattacatc
    14761 tgaacctaca ggaacttggt caaataacca tctaacatct ttattgtgca ttcttataca
    14821 tccaccagaa atatgctttc ctatagaact ctcattatta tttccatgta ttccatatgt
    14881 atctccataa gttcctttta atgctaatcc catccatcta tctcctaatg gatttcttgg
    14941 acttcctcca ggtatattac ctttataata tggtctattt tttatcttgt taactacttt
    15001 tgttttccct gttggtgttt ctgacccctt tttacctgtt gcaactctaa attcttttac
    15061 aagtttatta tttacaaaat atcctagagt attttttctt gaatttacta taatcacatg
    15121 tttactggct gcgcttgatt ctggtacgcc acatgcaaat actaaaacta aagtcagtgc
    15181 tagtactaaa tactttttta gacttttttt cactataact tccccctctt ttagaaacat
    15241 tactacatgt gtctaattat aacataaaat taccaatacc ttatatttac aaatttgtta
    15301 catttataca tataagtatg tattctactc ttcataccca ttaggattca tactttgcca
    15361 tctccatgaa tcttcacaca tctcttcaag ttcatactta gctttccatc caagctcttt
    15421 ttctgccttt gaagaatctg cataacacat ggctacatct ccagcccttc ttcctacaat
    15481 cttatatggt atttcttttc cacttgcttt agaaaatgct tttactaaat caagaacact
    15541 ataccccttt ccagttccta aattataaac aacaagtcct ggattttctt ctaatttttg
    15601 taatgctttt acatgaccag cagctaaatc taatacatgt atatagtctc taactccagt
    15661 tccatcatgt gttggatagt cattaccata aacactcaat tccttcaatt tacctactgc
    15721 tatttttgtt atataaggca ttagattgct cggaactcca tttggttctt cacctattct
    15781 accactttta tgagcaccga ctggattaaa gtatcttaaa agagctatat ccaatgactt
    15841 atctgctttt gatatatcta ctaacatctg ctctatcata agtttagttc ttccatatgg
    15901 attggttaca gaaagtggaa aatcctctaa tataggacaa gtatgtgggt ctccatatac
    15961 agtagctgaa gaactaaata caaacttttt aacaccatat tctctcatta attcaaataa
    16021 atttaaggta cttattagat tattgctgta atattcaatt ggtttttcta ctgattcacc
    16081 aactgctttt aaagctgcaa agtgtataat tgattcaata ttattttctt taaatacaac
    16141 atgcatttca tctttatttc tgatatcaat attataaaat tttactggtt ttttagataa
    16201 ttccttgatt ctatcaacca ctattgagtt gctattactt aagttatcaa ctataacaac
    16261 ttcataacct gattctaaaa gttctattgc tgtatggctt cctatatatc ctgctcctcc
    16321 agctactaaa actgccattg taattacctc ttttctaata tttatttttc acttactttt
    16381 tttctcatat agtccattaa atcatctttt aaattttctc tctttagagc aaagtctatt
    16441 gttgcctcta aaaaaccaat tttatctccc acatcatatc ttctaccttc aaagttataa
    16501 gcataaatag cctcttgttt tccaagagtt tgaagtgcat ctgtcagttg tatctctcca
    16561 cctttaccag gtgtctgttt ctctaatatg ctaaatattg caggagttat tatatatctt
    16621 ccaagtatag ctatatcaga tggagcttct tcaattgcag gtttttcaac catatcttta
    16681 actttatata ctctatcttc gatatgtttt acatccaata taccatattt attagtatct
    16741 tctttagcta tcttttgaac acctaataca gttgttttat actcattata agtatctatt
    16801 aattgtttta agcacggaac atctgaatct actatatcat cacctaataa tacggcaaaa
    16861 ggttcatcac ctataaaact ttttgcacag taaattgcat gtccaagacc ttttggctct
    16921 ttttgtctta tataatgaat atttaccata tttgatatgt ctcttaccat ttctaacatc
    16981 tctgtcttac ctttttgctc tagttctaac tctaattcaa ctgatttatc aaaatgatct
    17041 tctatagatt ttttatttct acctgttatt ataagaattt cttcaattcc cgattctata
    17101 gcttcttcta ttatatactg taaagttggt ttatctacta taggaagcat ttctttgggc
    17161 tgtgattttg ttgctggtaa aaatctagtt cctagccctg ctgctggtat tattgctttt
    17221 ttaactgtca tctgcatttt ttcacccttc ttcgtaaatt ttctattgta ccaaattaat
    17281 ataccatatt tatacttttt cttcaaactc tatattatcc caatatttaa tgctataaga
    17341 taatataagg tagatgaaat ttcatctacc tttagtttta taagttaata ttgtattgtt
    17401 tatattttat ccaaaactta tacaggtact aaatttcatc taagatgcct tttatatcac
    17461 tatctatatc ttcatctaga taagaatcta aatcttctaa gtcaacttct agttcttgat
    17521 atgtcatatc aacactgaca tcctcatcta tatccatttc tgatattaat tctcctaaaa
    17581 tactatttcc atcagaatct aaaccactat ctatatcttc atctatatag ttttcattta
    17641 aaatttcatc taaatcaatc tcgtaataaa cttcattatt tttttcatcc cctgagtcca
    17701 atcctaagaa ctcatagtta aaagtccaaa cattgtattt acttgacata ctttattcct
    17761 cctgtgaaaa acatattttc atctagttta ttggttccat aatcaacaga gttatatatt
    17821 ttttcaatta tgtcttttct tctttctttt gtactattat ttaatgtcaa ttgtttaaat
    17881 acatatgtat ttgttattct ctcgaataat atttctttta tactatcatc atcaatattt
    17941 ctatagtttt tccacaataa ctcaaataac ttaaacattt ccctactagt ttcatctaca
    18001 taataaggat acatattttc tactaaatgg tttaatcttg atatggcttg ttttaaaaat
    18061 acatcaagac ttgcactttc actttctttt aacattctat aattgtattt cttcttatct
    18121 tctcctgaaa ttacaaagat gatattgtct aaactttttt caacttcatt taaataactg
    18181 cttatattat atgataaatc agacaataga tttttaatct gcttaaacac ttgtacatca
    18241 agtttagtat tatacttttc aaacaaatct atttcttgat tttctaatat tcttggcata
    18301 tatgctgaca ataaatctaa attgtttctt tgttcttgta tttgcttata aagtgaattt
    18361 ataacttcta ttcttatttc atcatttaac tctttttcta aaatcttatc aaattcagat
    18421 ttcatatagt aaatatttcc aaagaaatta aatattatca tatcattcat agctttagac
    18481 caattcttat atatcacttc aatagaattt tctttaagta gaggttgctt tgcatatata
    18541 aatacatctt gcataagttt ttgaaccata cttttactta agtttaaaag tactttttga
    18601 ttattaaatt ttatttccgt ttctacaaaa ttagaatttt cgttttcaag ttctttatta
    18661 attacaatgt cttttatatc actatttttt atagatatga tttctttttg aaaagacttt
    18721 agaatagtca agctatcgaa atcttcttga ataaaaaatg gagcatgttt taatgtatat
    18781 cccactattt cattttctat atcttttagg tcatctattt gcataatttc tctattttta
    18841 tcatttatat gtaggttaaa tacattttta ttatcatata atattatatc ttctcctaaa
    18901 tttaacttag aacaattatc tttcgctgac tttacaatag tcttcttaga tttcttattt
    18961 ataaaaatta attggtcttg atattttact aaaagcatgt ttgtgttttt ataatcaaat
    19021 ccatctatat ttcctgatat cttgcagaat actatttcac aatctttagg aagatttcct
    19081 attttttggt tatctttaac tctctcattt aaatcagatg ggactacact atctatattg
    19141 ttattaaata tagatacaga ccttactata atcccctctc tttccatatg aaagtatccc
    19201 ttcaatgaca ctcttttatc ttctaaaatg tatctttcta tatcatcaaa atttatttca
    19261 aatctatttt tcccactgat aaatataaac ttctcattat ctttattaat tccacccata
    19321 taaaacttat tgtcatctaa acttaatata gtcatattat cctttagata gaatataaat
    19381 tctctttgac ttttgcagat taaatcatat tcatccaaag ttattttcat agtcaaattt
    19441 gctgtaacat ttttacttga attttcactt tttatgtaaa aaggcaagtt atttccatag
    19501 acaattattt gagaatcttc taaaactgcc tctaattttt ctttattgtc tgaaaaacta
    19561 tatatatatt ttacacctgt atcctcatta acttcatctg atttgctgat tattatattc
    19621 cctagatttg ttatatgaag ctttttatat tcttttgagt atctacttat gccactaagc
    19681 tcaaacccat ctgaaagctc atatatgatt ttttctccta atttcaacat accttcacca
    19741 cctaaacaga attataagta ttttataaag gtgaataaaa tgtctcaaaa caaataatat
    19801 tttttttaat actttttatt ctgagacata gtttctcctt ttttataatg ctctaagcac
    19861 cttcaactat ttcttcataa agtttatcta aatgtttaac atattcacga tatccagatt
    19921 tgttctttaa ctcacttctt aaatcttcat atttttgttt aagttcttca gcactcaaag
    19981 aaggagctga ttcttttaat tcttctaact tataatcata gtacttatca tacatagcta
    20041 tatatgtatc aatagacttc ttagctagtt cattacattt ttcttgtgct tctccatatt
    20101 gagaataatc acctattttt attttatagt atccattttc ttgaattatt gttgaagaaa
    20161 tacctttagc ttcatattct tttgctgttt cttttgctgt tttttcaact ttaagtgaac
    20221 ctgcataaac agtgtaatat acacctttac catctttata tgcttccatt tcttttgctt
    20281 tcttttcagc ttgtgctttt tcttgagcct ctttttcagc ttttgccttt tcttctgctt
    20341 cttttttctc tttttcagct tgtgcttttt tctcttcttc agttaattta ttgttagctt
    20401 gttgttgagt tgatgacttt ggaatattct ctttatcatt tttcttattg ttgcctactg
    20461 ttataaaata tcctacacca acaataacca ctataactac tgctataata gtttctttta
    20521 atctactctt cttagaaaca acctcttcat catctaaaga atcttcttta tctgatacat
    20581 aatttttcat ttctttcttg ttttctctat atttgtcctt agaagaattt ttagattttt
    20641 tattactatt ttctttcttt ttaataggta ttactactga tttttcattt tctaattttt
    20701 cttcttttat ttcttttgct tttttatctt ctaagttttt actttctttt tcaagcttcg
    20761 attcattatt tgaagatact ttttcatcta agttattatt tattggtttt tctattttta
    20821 cactacgttc ttcttctata tgttgacttg gttcttcttg ttttatttct ttcaattcat
    20881 tttgctctat ttcttctgat ttcacttgat gattttcaac tggtttatct aaaattatat
    20941 ctggagaaat atcatttaaa ttctcttctt cttgttcagc ttcttcattg tcttttttaa
    21001 taaatccaaa taatttagcc ttctttttac tctttttatt ttctggttca attatatctt
    21061 ctttattgct gtcgtactct ttatctgtag tatctttatc ttctacaacg tcacctatat
    21121 cttgattatt actatctact tcttctttag tcccttcttc agcatcatct tctattgaaa
    21181 tactacttct aaagcaaata tctttatctg cattttttat catgtaaatg tattcttcaa
    21241 tatcgatatc tttatttctt ctagttcttt ttgatgcaat ttcatgattt tctaattcac
    21301 tatagttatc ttttattaga ttctgtgctt tattccatgt atcttcacta atttctgttt
    21361 tatttttaat tacatagtcc acaaattcct taaaattttc aggaccaaat tctccaatta
    21421 tagtcagtct cattgcacct tctataaggt ctctatttct tctctttaaa aattctaata
    21481 caactgttgc acaagcaaaa tctttaataa tttctttgcc aaaaccatat gcttcaacag
    21541 aatgaagttc ttctaatcca cataacttct tatattcatt gtgtattgtt tgagatatac
    21601 tttcattatt taagctattt aacttatcta taaacttcga ttctatatca tttgattttg
    21661 attcatgttt tacttttgaa tttttaattt catttagtag catgtcattt tctgaattat
    21721 ctttacctaa ttgcaaatcc tcaatttcag ttgcttttat ttctactttg ttttgttcgt
    21781 tattctcttc cacattatta ggtaccacat ctttattact agctaatatt ttgtttacac
    21841 agaatataat ttctcttttt aattctcttt tcgcatctgc ttgattttta agaaataaat
    21901 ctccacattc tttcttttct aaacttattt ttctaagaga tatattaaga aggtctttat
    21961 ataggtttaa aaccttataa tccttttcta aacgtcttct tctctctgat agttccattt
    22021 tatcataagc taaaaaacta tttaaatcat tggcttttag agagtctaat ccctctttca
    22081 tagccttatt tacatacttt ctacattttg ctgtagttaa ctctaaatct ttttctaatt
    22141 catctatttc aggtatgtac ttatctacta tccatttgcc aataagtggt tctgtatttc
    22201 ttgctaatgt cttataaaac aatatattaa attttaaaag ctctgcatat tttgcttcat
    22261 taaattctac tttttcaaat ttcttttcca aaacaccatc tagcttttca tttattttag
    22321 actcttgttt taaaaaactt gctgtgacat ttaaaacagt gtttcttatt atattatttt
    22381 cactcaaaac cttcactcct taaatcaatt attttattgt aatatttaca ttgtgcaaag
    22441 ttgctaattt gattatgata tctaaataat tatttactaa atttgctaca tcttatatca
    22501 tatcatatta tttacatcat tttacttttt ctttttatat ctatcttata ttataccatt
    22561 tttaatatct gtactaactt atattacaat attcctcaaa attttaaaag tagattagac
    22621 aaatttacaa ataaaaaaac atcagtttaa actgatgttt ttgactatcg aaataattaa
    22681 gcaagtctat aagcggagtt ctgtattaga taatcatctt tctaggccta ttgtcaccaa
    22741 taggctcaag cgacctacct accggagagt acgagcagca ctctttattc ctatcttggt
    22801 cttgctccag gtggggttta catagccaac tagtcgccta gctgctggtg agctcttacc
    22861 tcgcctttcc atccttacca caatagtggc ggtttatttc tgttgcacta tccttaggat
    22921 cgctcccact aggcgttacc tagcaccctg ctctatggag ctccgacttt cctcatgtaa
    22981 gattacatgc gattatctgg cttacttaat atttatttta cttagttatg ttaacacaaa
    23041 ttcttttaca tgtcaaagta atattatact aaaaatttaa atttattcaa aaatagtgta
    23101 atatagatat ataaactaca tttaactcga ggtgatctat tgaaaaaatt atatagaata
    23161 gtaattaaca ttatactagt attagtaata ctttacagtg gatttaatat atactcaaaa
    23221 cttaccaaat acaatcatga tactaaaata tcctcagaac ttcaaaaaaa agaatataaa
    23281 aaagaggatt tatcaaagat taacagtgat tttaaatttt ggctttctgt tgagaataca
    23341 aatataaatt atccagttgt acaatctaaa gataattctt actatcttga caaagatttt
    23401 tataaaaaag attctatttc tggtacactg tttatggatt atagaaataa atctattgat
    23461 gacaaaaata tcataatata tggacataat atgaaaaata aaactatgtt caacaaccta
    23521 aataagttta aagatgctga cttctttaaa aaaaataata aaataaaaat aaccttgaat
    23581 ggaaaagaat ttttatatga tgttttttct gcttatattg tagaatctga ttatgattat
    23641 ctaaaaacaa attttaacaa tgaatctgat tatcaaaatt acataaatga tattacttct
    23701 aaatcattgt ataaatctcc tattaaggta aatagcaatg ataaaatagt tacactttct
    23761 acatgtacct atgaatttga tgatgccaga atggtgattc atggtagatt gatttaaaac
    23821 tcacagacac agtttaaaac aataatttta aactgtgtca tcttttatac ctataatttg
    23881 taaattagac cactaaaagt atttaataca aaataacaaa tacatcaaac aataaaaaac
    23941 aataaaaaaa gactatgcta aaaacatagt ctttactgga gctggtgata ggaatcgaac
    24001 ctacaacctg ctgattacaa gtcagctgct ctaccgttga gccacaccag cacacctatt
    24061 ttattgtaaa ttagcaaaac taatttttaa aagtta
//
LOCUS       DAEHWO010000057        23917 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEHWO010000057 DAEHWO010000000
VERSION     DAEHWO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.057"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            138..836
                     /locus_tag="KNP54_002689"
     CDS             138..836
                     /locus_tag="KNP54_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893562.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            1014..1904
                     /locus_tag="KNP54_002690"
     CDS             1014..1904
                     /locus_tag="KNP54_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893563.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(2297..3253)
                     /locus_tag="KNP54_002691"
     CDS             complement(2297..3253)
                     /locus_tag="KNP54_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBF0893564.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            3956..4951
                     /locus_tag="KNP54_002692"
     CDS             3956..4951
                     /locus_tag="KNP54_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0893565.1"
                     /translation="MSIIELNELTKAYRRFEKKAGFMGSVKSLFNRKYTEKTAILSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            4929..5792
                     /locus_tag="KNP54_002693"
     CDS             4929..5792
                     /locus_tag="KNP54_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBF0893566.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            5789..6583
                     /locus_tag="KNP54_002694"
     CDS             5789..6583
                     /locus_tag="KNP54_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBF0893567.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            6868..8247
                     /locus_tag="KNP54_002695"
     CDS             6868..8247
                     /locus_tag="KNP54_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0893568.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            8695..9408
                     /locus_tag="KNP54_002696"
     CDS             8695..9408
                     /locus_tag="KNP54_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893569.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(9680..11218)
                     /locus_tag="KNP54_002697"
     CDS             complement(9680..11218)
                     /locus_tag="KNP54_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBF0893570.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            12100..12555
                     /locus_tag="KNP54_002698"
     CDS             12100..12555
                     /locus_tag="KNP54_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBF0893571.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            12604..13188
                     /locus_tag="KNP54_002699"
     CDS             12604..13188
                     /locus_tag="KNP54_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBF0893572.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(13193..13516)
                     /locus_tag="KNP54_002700"
     CDS             complement(13193..13516)
                     /locus_tag="KNP54_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0893573.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            13668..14186
                     /locus_tag="KNP54_002701"
     CDS             13668..14186
                     /locus_tag="KNP54_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0893574.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(14362..15030)
                     /locus_tag="KNP54_002702"
     CDS             complement(14362..15030)
                     /locus_tag="KNP54_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893575.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            15145..16560
                     /locus_tag="KNP54_002703"
     CDS             15145..16560
                     /locus_tag="KNP54_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBF0893576.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            16783..17241
                     /locus_tag="KNP54_002704"
     CDS             16783..17241
                     /locus_tag="KNP54_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0893577.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            17238..17822
                     /gene="clpP"
                     /locus_tag="KNP54_002705"
     CDS             17238..17822
                     /gene="clpP"
                     /locus_tag="KNP54_002705"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBF0893578.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            18134..19210
                     /locus_tag="KNP54_002706"
     CDS             18134..19210
                     /locus_tag="KNP54_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBF0893579.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTDGGFKSDDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            19277..21352
                     /gene="bclA3"
                     /locus_tag="KNP54_002707"
     CDS             19277..21352
                     /gene="bclA3"
                     /locus_tag="KNP54_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBF0893580.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAVGATGIGIT
                     GPTGPTGATGADGATGVTGPTGATGATGADGVTGPTGATGATGFGVTGPTGPTGATGI
                     GITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGATGADGATGATGATG
                     ATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLV
                     GPTGATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATG
                     LAGATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGATGPTGA
                     TGATGATGPTGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDL
                     TNAAGTLTNFAFSMPRAGTITSISAYFSTTAALSLVGSTVTITATLYQSTAPNNSFTA
                     VPGATVTLAPPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAG
                     YASAGIAIN"
     gene            21521..22282
                     /locus_tag="KNP54_002708"
     CDS             21521..22282
                     /locus_tag="KNP54_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBF0893581.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            22591..22869
                     /locus_tag="KNP54_002709"
     CDS             22591..22869
                     /locus_tag="KNP54_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893582.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            23162..23737
                     /locus_tag="KNP54_002710"
     CDS             23162..23737
                     /locus_tag="KNP54_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBF0893583.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
BASE COUNT         8918 a         2862 c         4032 g         8105 t
ORIGIN      
        1 aaattttttg ttgaaaataa tgctcgaacc tataaaacta ttaactaata tttgtaaatg
       61 tatacttttg atgataaaat ataattaagt taagttggtt tttataaaca taaatttatt
      121 ttaaggaggt gaaataaatg aaaatatcta gtcaatatag aagtcaatat tcatttagat
      181 atgaaagtaa tataaataat acaagaataa atgaaagtat ggttaagaaa aatgaaactg
      241 taggaaaaga cacttattta tctaatatta tgaaacaaaa gcaagaactt aatgatagaa
      301 ttagagattt aaaatataga caagaggttt atactaaaaa aataaatgac gcaattaaga
      361 acttatgtaa atcagaaata agagaaacaa ctaataattt ttctaatata gaaataggta
      421 ttaaaaatag cattatagaa gagaaaaata aaagtacaat gttagatgaa aattcaactt
      481 atctaaatac aaatgatgaa aaagaatctt taatcactaa agagtctaat gaaaaaattg
      541 aagaagaaat attaaatgat gaaaaattag aagagttaga acaaaaaaag gattataaag
      601 aggattctaa taaaaaagag aaagtatctg aggacttatc tttagtaggt aaaactcgtg
      661 aagagcttga aaatatgctt aaaaatttta taaatttaac acaagaagaa ataatgaaac
      721 ttgagtcgag aatagaaaag ttagataaaa atgctgaaga atacaaacaa aattcaaaga
      781 ctaatatatt tgataaaaca gatgaacaaa aaaaacatat aaatgtactg atttaaacaa
      841 tatgttttaa aaaaataagt ttattatata atgaaaatat aaaggtacaa tttcaataca
      901 cttctattaa accaataatt tatgaaccag acttaatttc aatttactaa taaccatata
      961 tttatgagtt aatagtttta tgttttaaaa agaattaaat aagggggagt agtatgaaga
     1021 agaatatatt aactactatg attaccatga ttattatatt gatgatgagt atgacagtaa
     1081 tggcagagcc atatcaagaa gatgaaacat ctagcttgaa aaaacagagt gcaaatgaac
     1141 gtaatcagac taatataggc acaatggatg gcagagtgca aacaaatgca ataagtaaag
     1201 gtgctaatta tgaccctaaa tatcctctta aaggaatgtt aacacaactt ggtcttaata
     1261 caacaggtaa agagggatgg gatttactct atggaggaaa tcccaatgga gttgagcttc
     1321 gagcagatgg taaatattat tatataaata agggtatgga agggctagga ttttatgcgg
     1381 cagcattgtc aggtggctca tatcagagaa taggctttgg aaaacttgac cctatagaag
     1441 taatagctga tggaaattgg atttcttaca aacaagctca agatacactt acagtaatca
     1501 ggaatttttt aaatagcttt gactggagaa atgcatctga gatggaaaga gctaatagag
     1561 ctgcaaaatt ggtaaccgaa gcaaaatatg cagactctaa atattgtaac atagtctatg
     1621 gtaatctggt tgataaacgt ggtgtatgtg gaagttttgc aagtagcttt catttattaa
     1681 caaggttaat gggaatggat tcactatcta tattaaatcc atcattaaat catgcttgga
     1741 actatataca aattgatggg aaatggtata ggtttgatgg gtctgaaata tcagcttttg
     1801 gtggatcatt agactttgat taccgtaaat taaaggatgc aacaagagag atgactactt
     1861 actatgatgc taaggcattg tctatattag gatttaatca ataaaaatag ggggaggctt
     1921 cttatagagc ctttttttat tgatttgaaa tttaataagg aattttatat gaaaatttaa
     1981 tcaataaaag caaaaaaggc tctttataaa gcctttctaa gtgttttttt aagtaaaatt
     2041 ttttatatca acatcagttt taatcaaaac atataacatt ttggacttac ttttaaaaat
     2101 aaaattatta aaatataata ttaatcatgt ttttagttta ttatattcta taatagtggt
     2161 catgttgact attgtagttt tattaagaat agttggttta tataaatata tgcaaagata
     2221 gcttgttgtt tactttactt attagtatat aggacaagat actctaataa atttgcctat
     2281 tttaatatct tttgtactaa aaccaactaa agtttccttt attatttcgt tttgaataat
     2341 acaaagcata atccgattgt ttgtataaag actggaaagt atcagagtta ttttctaatt
     2401 tagatatacc tatagaacaa gaattactct ctaggcataa ttctaaaacc ttctttgcct
     2461 tattttcaac attctctttt gattgattac tatattcaaa aacagcaaat tcatctccac
     2521 caagtcttcc aataatagca tcatttacga atactttagt caaaatattt gaaaaatgta
     2581 ttagtatttc atctcctcga acatgaccaa agatatcatt tacctgttta aaattatcta
     2641 aatcaaagat gtaaaagtat ccatgtgaaa cagttttaag catttctttt atgtgtactt
     2701 caaaaaaatg tctattgtat agtccagtca taaggtcttt ttctgatttt agtttaaatt
     2761 catttgccat tgctagtgct tcttgtgctt tttcagttat tgttttaggg taatactcat
     2821 ctttcatttg gtcaaagttt ggaatagaat ggtgaacatg gataagttta atcatatcat
     2881 ctgtaactct gtataccata gtaaatcgag tatccatttc tacatagata tctttttcta
     2941 ggtaatcttt ttctattacc caaagagtac catatactat aaaagcttcg tctgtgactt
     3001 tggtacatga ataccactca tctataatct caaagtctat ttgctctgat tctgtttggt
     3061 ctttttcaag acctataata aattcttcta atgtttcgta aaattcatgt tttcctgttc
     3121 caattaatgc aaggttgtca tctaataagg aaataataaa tttaaggttt tcttcttctg
     3181 gatttaaaat ataaatatgc caaatttttt ttgataaatc tcttaattgt ttttgtattg
     3241 tattattttc catagattac ccccttaaga tttacagttt atattttaat gtattataag
     3301 ttgaactctt attacaatat tattataata tagaactaaa gaaattacat cctgtatagg
     3361 taaaagtata tcttttacaa taaaaatatt acagtaaaat gaccagtttt aatatacgta
     3421 ttatattttt aatttataaa cgaatattat aaatgaaatt taaattcaac cttgaagaaa
     3481 taagctaaat gtattagtat attaatccat gcttgaacat aaataacctt tatgatatga
     3541 tatcaataat aatattatga gaggagtgcc ttgatgtcgg agttatataa tggtaaccaa
     3601 caattaaata gttggagaca catatattct gtataatcag aaatttcaag tgtattttta
     3661 atacatttaa tttttgtgtc ttattctgcc tttatagata actgacatat gacaacaaat
     3721 agtatttaaa atatatatta ctttgttaaa ttatggtgta gtaggcttta atctgctaca
     3781 cttttattaa ttttgtatag tattattttg ataactattt tgaaatagag agcattaatt
     3841 tttctagtcc acaggagttt tctgtttttg tgctgttaaa tataagcaca gaaaaaggca
     3901 gatatatacc tgtggacttt ttttatataa attatgaaat atggaggtag ttaaaatgag
     3961 tataattgaa cttaatgaac tgactaaagc ttatagaaga tttgagaaaa aggcaggatt
     4021 tatggggagt gtaaagtctt tatttaatag gaaatataca gaaaaaacag ctatattgtc
     4081 atttgattta aagatagaag aaggagaatt tgttggatta ataggtcaaa atggagctgg
     4141 taaaactact cttattaaga tgttaactgg tattattgca ccgtcttctg gagaaatatc
     4201 tgtaatgggt tattacccta acaaattaga aaataatttt aaaaaacaat atgctgttgt
     4261 tatgggccaa aaaagtcaac tattctttga attgacacca gcagatacgt ttcttttatt
     4321 taaagaatta tatgatatat ctaatgaaga atataaaaaa aacttggatt actttatcga
     4381 attatttgag gtatctgact atttaaatgt tcaagttagg acgctttctt taggagaaag
     4441 aatgaaaatg gaactaatag tagcccttct acataatcca aaaatattat ttttggatga
     4501 accaactata ggcttagatg ctatagccca aaaacaaatt aggtatttcc taaaagaagt
     4561 aaatgaaaca aaaggaacta ctattatact tacttctcat tacatggaag atattaagag
     4621 tctctgtagt agaagtattg ttgtagaaaa tagccgtaaa atatatgatg gttctacaga
     4681 gaaactattt aatcattttc aaaaatataa aaaaataaca gttagttttt ccaatgaaac
     4741 taacattgta tttccaaaag attgtaaagt tgttgaacaa acaaatcata agatatcagt
     4801 aattgtgcca aaagaaagag gaaatgaaac gattaaatgg atttttgata aatatgatgt
     4861 taaagatgta atgattgaag aagaagatat aggtagtatt gtagagagaa tatataagaa
     4921 aggaagtgat gagtattatg agcaactata atgaagcaag ttcaaatgat tcaatgtttt
     4981 ataaatttaa acagagtatt agaaggtatt atgaagtagc caaaattaac tttaaagtgc
     5041 aacttatctg gagatttgat gtggtggtta atatggtgtt tacgattgta aaaattttat
     5101 ttgcttatat tttatggaaa gcaatttttg gtgaaaataa aatagtctct ggttttacat
     5161 ttaactctat gttgtcttac tatataataa gctcattttt agcaggtatt gatatgtcaa
     5221 agagtaccag tgaagagata tgtaatcgtg taaaattggg caccttttca aagtacatga
     5281 ttattccaat taatgttcaa aattatttta ttgctaaaaa ttttggaatg acatgttttt
     5341 attttgtatt taatatgatt tctgcatttg tatggatttt tatatttaaa atagattttg
     5401 cctttacatc aaatccagtt caaatattaa tttcaatttt gatgattttt ctagggttta
     5461 tttttatgat gaaactccac ttctttattg ggattttgtc atttaaattt cttgagatta
     5521 gtttttttaa aatgataatt gaaaatattg ttgaatttat tacaggaaca atgataccac
     5581 ttgtactctt accagaaact atagtaacag ttatgaaggt atttccattt tattatacaa
     5641 catatttgcc atctatgtta ctaataggta gaaacagcaa tgaggcaata caaggattaa
     5701 ttattctagc attatgggtt ttattttttt ctgtagtaaa taaagttatg tataaaagaa
     5761 tgagaacatt atttgatggg gtgggtatat gatgaaaaaa aatttgaaaa taatatttat
     5821 gttattaaaa atgaaattat caaagatgat ggtatttaga ttcgattttt ttggagcatt
     5881 ttttgtagat agttcattat ttatattaca acttctaatg tttaatagta tatattctca
     5941 tgtagactca atagggggat ggcaacaagg agagatgtta atatttatag gaactttctc
     6001 attaataaat gcgataaata tgacgatttt cttttttggt atttatgata ttccacgaaa
     6061 aatccaagaa ggagaattag actactatat tacaaaacca ttagacccac tatttaggtt
     6121 aacatttgaa aatattaata ttggttcatc accattaatt ctagcaagta tacttattgt
     6181 tttatatgga atatctgagt taaactcaga gataacttta gttatgataa taatatatat
     6241 tttcatggtg ttattgatga cattactttt ttatgatgta tgtatcatac ttagaacagt
     6301 ttcatttttt gttatatcat cttctgcgat aatgagatta gaagataatt tattgccaat
     6361 gaatatgaaa attcctggtg taatatatga aggtgttttt aaagtattat tctatttaat
     6421 cttaccatat ggaattatgt cgacaattcc gactcaaatt ttggctggga caataacaat
     6481 taatggatta atatactcaa ttttaattgt atttttgttt acattgttta tgtggagatt
     6541 ttggaagtta ggtatgagac attataaaag tgcaagtagt taataaatta gtaaaaatag
     6601 acaatgtata actatatata aatacgtttc atatgacact aaactatgtg aacaagtatt
     6661 tgcgctaaag gcactgaaag ctataaaatt attaaagtaa ggatttaaaa gtttctttag
     6721 tagaaatata attgtgtaaa aaagcaagat taattaaaac tatatccaaa taattagata
     6781 taattcttat gcagaaagga ggtctgtaaa tgtctaattg tttggaatat attttaaaaa
     6841 taattaatgt acagaaaaat aaacaaaatg agtgatgtat attattcaga aaatcatgaa
     6901 caagataatc tttatgagca agataattta ctggcacaaa gatttaattt atttactcta
     6961 ttgaagtttg catttcctac tatttttatg atgattttta tggggttgta tacaatcgta
     7021 gatactatat ttgtatcaag atttattaat acaaatgctc tatcagcaat taatattgta
     7081 tgtccaatta ttaatcttat agttggaatt ggaactatgc ttgccactgg aggaagtgct
     7141 attgtagcac gtaagatggg aaatggtgat attgagggag caaataaagc tttttcttta
     7201 atcgtattat caggagttgt aattggggta ataattactg gtataggtat tgtatttatg
     7261 gattatatca ttatatggtt aggagcaagt gaagttttaa ttaaatattg tcgttcatat
     7321 ctttttatta tcttggtttt tgcttctgca aatatactac aagtattatt tcaatgttta
     7381 tttgtaacag ctggaaagcc tcaatttgga ttatggctag tgttaggtgc tgggtgtgct
     7441 aatataattc ttgactatgt gttcattgtt ctgttacaaa tgggtattag tggagcagca
     7501 cttgcaactg gagtaggata cctaattcct accgtttcag gtatggtttt cttttcaaaa
     7561 aataaagggt tacttaaatt ttgtatacct agactagata aaagaatatt atttgaagct
     7621 tgttttaatg gttcatctga aatggtgggt caactatcaa cagcagttac tactttttta
     7681 tttaatgcta tgatgatgaa attaattggt gaagatgggg ttgcagctat tacaataatt
     7741 atttattctc aatttctttt aacttcgctt tatataggtt tctcaatggg tgttgcacca
     7801 ataataagtt ataactatgg aagtgaaaat aatacgcagt taaatcatgt ttttaagatt
     7861 tgtatattat ttatttcagt agcatcttta ttggtattta tcttttctat atcatgttca
     7921 ccaatcattg tagagatttt ttctcaaaga ggaagccgag tttatgaaat tgcaaggtct
     7981 ggattttata tattttcttt tagttttatt ttttgtgggt ataatatttt tacttcgtct
     8041 atgtttacag cattatcaaa tggaaaggtg tctgcaatat tatcttttct acgtacattt
     8101 ggatttataa ctataggttt attgatattg ccaaatatat taaatataaa tgggatatgg
     8161 ttagcagtac caagtgctga gattttaact ttatttttaa ccattttttg tatatgtaag
     8221 tataagaata gatataaata tatgtagata ttaaataaat agtttaggta gatattttat
     8281 gttttaataa gtaattcaat tagtgggaga tatatactat tgaaaattaa agttataatt
     8341 gatataaaga attaataaaa ataacatata aaagtttaaa agggagttga acttaaagtt
     8401 tgattagaaa aagtcaattt taagacaact ccttttattt tactattgta ttaatctgta
     8461 tctgtaagtg tattagtcta atattataaa ctttggatga aattaatttt ctataggttt
     8521 taatgtatca tacactttat tttaaagaaa cttatcttaa ttttcatagt gattgaattt
     8581 gtctattaga gatgttacta ttagtaatgt aaaagcaaga gtagtgaata taaaaaacaa
     8641 gatagtgata ctgcaagatt agaatataat aaatttttat ggagagattt caatatggat
     8701 acatgtttta ataaaaaaat attacttgtt gatgatgaaa aggatatagt agatttaatt
     8761 gaagaagtac tcataaatga tggttttaaa aacattatta aagcttataa tggtctagat
     8821 gctatttcgc tgtgtaagat agcatgtcca gatgttgtca ttcttgatat aatgttacca
     8881 gatatagatg gtatagaagt gtgtaaaaaa attcgagagt tttcatactg ttctattctt
     8941 tttttatcat caaaaaatga tgatattgac aaaatactag gtcttagtag tgggggagat
     9001 gactatataa caaagccatt cagtccaaga gaaattgctt ttcgagttaa agcgcaatta
     9061 cgtagacaac agtatcaaag cattgtacca tcagatagtg aagttattaa aataggagat
     9121 attactattg atatagaagg aaaccgtgta tataaagata gaaatgagat tgagttaact
     9181 ggaagggagt atcatctttt aagctacatg gctcaaaatg taaataaaat tataggaaaa
     9241 gaaagactct atgaacaagt atggggagta tatagtagta tttgtgacaa tacaattatg
     9301 gtgcatatac gacatataag agaaaaaatt gaagataacc cctcaaatcc taaaatactt
     9361 ataacagtta aaggactagg atataaactt gtgaatagaa tcgattagaa tagattttaa
     9421 tattaatgaa gatatctcaa gttgaatttt tagttaatga ggcattcttt tatgggtaaa
     9481 atcaaatata ttttcgttat ctcaacaatg aagaagaggt ctatctctat tttgagatag
     9541 cctcattaag tttatatcct ggtaatgtac tttatcttct aataaaattt ttttagttta
     9601 tttgcagtga aacattaact agaacattaa aatttgcatt gaaatactaa ttaaataata
     9661 ttgtatattg tgtataaact tatactaatt gtttttctat attaaatact ttatcaatcc
     9721 aacctttata aaatttttct tcatgggaaa ctaggattat acttcctcta aactgtttca
     9781 aagcattttg taaagcatcc tttgtctctg catcaaagtg attggttggt tcatccagga
     9841 taagaaaatt acaaggagat aacatcatac aacataattt aaccttagat tgttcaccac
     9901 cacttaaagt agatacactc cttgaaacat gctcttcctt cacaccacat ctggctagat
     9961 gacgtctaat ctcttttgta tttaattttg gatatttatc tgctactatt tgaagtgggg
    10021 ttttatcagg attttcccat tttaaatctt gctcataata accaatttta acttgttctg
    10081 aaaactggaa atctccagat atacgaggaa tatctttgac taatgtcttt aacaaggtag
    10141 atttaccgat tccattaaaa ccagttataa ctattttttg acctccatca acagagaaat
    10201 ttaattttgg aagtaaagaa tagtagtatc caacttcaag atttgttata gtaagagcat
    10261 tttgagccga tatttcaatt tctgaaaatt gaatatttgg ttttcctgta aaactaggag
    10321 gagctattct ttctatttta tccaattgtt tttgtcttcc tcttgcaatt tttgaattta
    10381 ctccagcttt atttttacgt ataaatgttt cttctttttc tattttcttt tgttgtgctt
    10441 gataccttct aatataatct tctcttaaat gtgatttttg tttaaggaac tctgaatatt
    10501 ttccatgata tttcttaatc atgccaaatt ctatatcaag aatacctgta gaaatttttt
    10561 ctaaaaagtc aaaatcgtgg gaaactacaa taaatgcccc attaaatgta tttaaataat
    10621 ttgagagcca ttcaacatgt tctttatcta aaaagtttgt tggttcatct aataatagaa
    10681 catcatggtt agaaagtagt aattttgcta aaattacctt tgccctttga ccaccactaa
    10741 gctctccaac aacacgattc attcctattg aatctaatcc aagaccattt gctattttat
    10801 ttatttcatt atctatagaa tagaaattac ttgctattag ttgttcctga taatctgatg
    10861 ctttgattag atattgctca ttttcagata tagcactttt ttgatagagt aaattcattt
    10921 ccttttctat tttataaagt tcttcaaatg cagtgtgtaa atagagtgat attgttgtat
    10981 ctctattgat ttctgcatat tggtctaaat ggcctatatt gatattaggt tgccacttga
    11041 tttctcctga atctggaaca acttctccca ataaaatttt aattaatgta cttttacctg
    11101 taccattttg gccaactaca cctatatgtt cacctttgaa taaatcaaag ttagctttct
    11161 catacagtga tttatccata aaacattgtg ataaattagt tacttttaat aaactcataa
    11221 ttcaaactcc ttttctttta ttaaaaaatt tatggaaata aaaaaagcag aggaatggca
    11281 ttgtaaaatg ccgacctctg cttttggaaa aacaaaaggt catagacaag cattgttgtc
    11341 tatgaccaga aaatctatat tatctatcgg caaataggta attttaaata agcatagcca
    11401 aaaaactata ctaaacctat atttgccgat gaagatagaa agctttaagc tttcagatta
    11461 acctctacac aacgcttcat cgtatacatt tgtgtagagt taagttttct aacaagttta
    11521 actaattcta tataaatcat aattattcac atcctaatct tagtattaat tctagtttat
    11581 ctgtatttaa attgtacttt tgtactttgt ggattatctt atttatttaa aatatgtttt
    11641 attaattata gcttaagtta tgttatcata atacttagtt atagtcaata agaaagttat
    11701 atttactatt attatattaa tttagtaaat ctatcattac aaagttattt gaagactcgc
    11761 tatcaataaa attttatagt ctataagaaa attaagatta tgagttttat aattttgata
    11821 tagggatact attttcataa atattacaac atgtagaagt atatgtctat tattgttgaa
    11881 ttttcaatga tatattaagg ttctaatata ttatacaaaa taaaaacatt aattcaactt
    11941 aaataatttt aagtattata tgtgttttga ttaaagaaaa ctaaaatttt aaggaaaaat
    12001 aacatatttg tattaaattt tattgaaatg attaaattta tttacttaat gtaaattatt
    12061 agctaaaatt gtattaaata attaaggagg tgagtagctc tggatgaaat agatttaaaa
    12121 ataattaatt ctctaaaaaa gaatagtagg gcttcaacct ctgaaataag cagacaaatt
    12181 aatttatcag taccagcagt ctcagagcgt ataaggaaaa ttgagcagtc aaatttaatt
    12241 caaaagtaca ctattcaaat taatcgggaa aaaacaaaat ataagctttt ggcttttata
    12301 tttatcaata ctgatttatc taaaagtatg aaagaattta agaaaactat attggaatat
    12361 gatactgtat tagaatgtca tcatatttca ggagagtatg attacttaat aaaagtatta
    12421 gcagaagata caagtaatct tgaagagttt atatcagtga ctttgaagga aattgggggg
    12481 attcaaaaag ctaatacaac cattgtttta tctacaatta aagaagaatt taatacaata
    12541 aaagatattt tttaaataat ttactagtaa agtgttaatt atattttagg aggaaaatag
    12601 aatatgaaag ttttagtttt tttagcaaaa ggttttgaaa ctatggaatt tagtgtattt
    12661 gtagatgtta tgggatgggc tcgtaacgat tatgggcatg atattgatgt agtgacttgt
    12721 ggatttaaaa aacaagttat gagcacattt aatatacaag tattagttga taagacgata
    12781 gaagaagtat gtgttgatga ttatgatgct ctagctattc ctgggggatt tgaagaattt
    12841 ggattttatg atgaagcata tgattcatct tttttaaatc taataaggga gtttaattca
    12901 aaagaaaaaa taatcgcttc tatttgtgtg gcagcattgc cagttggaaa aagtggtgtt
    12961 ttaaaaaatc gtaaagctac tacatatcat ttgaaaaatg gtaaaagaca aagacagtta
    13021 agtgagtttg atgtaaatgt agttaatgaa ccaattgttg tagataaaaa tattataacc
    13081 tcatattgtc cagaaacagc tccacatgta gcttttaagc ttttagaaat gttgacatct
    13141 aaagaacaaa tggatgaagt taaattagca atgggattta aactgtaatg gtttatagat
    13201 tttctaagta atcagaaccc cagtcacaca tggaatctaa aattggaata atactctttc
    13261 caaaatcaga tagcgagtat tctacttttg gaggaacaac aggataaacc actcttataa
    13321 ttaaaccatc tgattctaat tcacgtaatt gttgagttaa catcttaggc gttgctttag
    13381 gaattaattt ttttaattca ttgaacctca atatagtgtc tttaagatgc caaagtataa
    13441 gtgtcttata tttaccacca atcaatgcaa gtgttgcttc tattgggcaa ctgtaattat
    13501 ctaaacattt tttcattttt gggctccttt atttatttta aagtatcttt ttaggtacta
    13561 tattacaaaa aagtgcatta ttgtaatata gtaccatagt gataaaatta tagcataggt
    13621 taaataaatc atcaacttag cctaataaaa caataggagg taaataaatg aatttcgttg
    13681 aacttgcaaa aaaaagatat tcttgccgta attatcaaga tagaaaggtt gaaaaagaaa
    13741 aacttgagaa ggttttagat gttgcaagaa tagctccaac tggtggtaat cgtcaacctc
    13801 aaagattgat tgttattcag gaaaaagaag gtataaataa actttctaag gctgccaata
    13861 tatatgatgc tccattagca attcttgtat gtggagataa agacaaagtt tggacaagac
    13921 cttttgatgg gaaacaactt acagatattg acacaagtat agttacagac catatgatgt
    13981 tacaggcaac tgaacttgga ttggcaagtg tttgggtgtg ctattttaat ccagatataa
    14041 ttagagaaga gtttagtttg ccagataatc tagaaccaat aaatatatta ttgatgggat
    14101 atgaatctaa gataccagag agcccagaga gacatgaaaa aactcgtgtt cctttaagtg
    14161 aaattgtttc ttatgaaact ctttaattat aaaattaagt tattcatagg ataaatgtaa
    14221 taaagtgttt attataaaca aaattcaaaa taaataatat ctacatataa ttaattttag
    14281 tgaagtatat ctagtttaac tagaatgtat acttcactaa tttatttatt caaaatattt
    14341 atgaggattt taatatatta actaaaatat atcaattgaa ttaactttta aatctggaaa
    14401 agcacttgaa atatagtgtt ttatgtcatt taaatggtct tgaatttgct tttctgatat
    14461 tttatcaggt ccatatacaa aatacataat atttttagta tcttttgtta tagctgttcg
    14521 attatcaggg ccattaagaa tactagataa tataccaata ttatctgata aaaataaatc
    14581 atcttttgtt aaaatatgtt ctttaccacc tataccataa aaatgttcac ttccatttgc
    14641 taattctatt ttcaaaggta attccatttt atcaaggtca tgacctgctg ttagaagaag
    14701 atttttcaat tctgctaaaa acattgactc aattgttaca cctacatctg ggataccttt
    14761 tgattttaat agaatagatt ctaattgaag caatacaggg taagttttct tgaatttttt
    14821 ataatacttt atataacttg aaacaggctc tgttttaatt ttttctttac gattgtattc
    14881 tgggtgttgt tctataatat ttttaattgt agagttttta agaactaaaa aattttcttt
    14941 attaggtttt gaatgtgtaa tatttataac cataactcca aatttaatat tgggataaat
    15001 ttctttaact ttatgtgata tttctaacat aatatagact cctttttatt ttatatttta
    15061 tgatataatc ttagcaaatt aaaagtggat tttgtagttc catttttata gtaattttat
    15121 agaaccactt ttggaggtat tagaatgtgg attacgatta atagaaatag taatatatca
    15181 ttatcaagac aaatttattg tgagataaaa gatatgattc tggatggaag cttaaagttt
    15241 gagcaaaaac tgccatcatc taggacttta tcaaaagaac tatctgtatc tcgtaataca
    15301 gttttagatg catataatca attaattgca gaaggatatt tggaaacaag gaatggatat
    15361 ggaacaattg tagctaaagg aatatcaggg cataaagttg attttaagtt aaatgatact
    15421 tttagagatg aaaaagattt acatactaat aaacaaaaaa attatataga ttttcgttca
    15481 ggagttccag aattaaaact atttccacgc aaagaacttt caaagctata taaacaaata
    15541 ctgtatgatt tatcagattc ggatttcaga tatggaagta cagctggtgt atgggtttta
    15601 agagtggaaa tatctaagta tttatttcgt actagaggaa ttagatgtaa tcccaaaaac
    15661 attatgattg tttctggttc aacacaaggt ttatctttaa tttcacagct tttatacaaa
    15721 agtaataaaa aggttgctgt agaagaccct attcataaag gcttattaaa ggttatttca
    15781 tctattggat attcagttgt tggaattaaa gtagatgata agggaatgaa taccaactta
    15841 ataaaatcaa taaaggggat ttcttttgtt tatactacac cttctcatca atacccatta
    15901 ggagggattt tacctattca aagaagacta gagcttatta aatgtgcaac agagaatgat
    15961 tactatataa ttgaagatga ttatgatagt gaatttagat atgagggtca accaattagt
    16021 tctctttatg aacttagtcc aaataaagta atttacatag gttcttttag taaaatatta
    16081 tctccagcta ttcgtgttgg atttatgtta ttaccagaca atattttaga aagctataaa
    16141 accttaaaaa tgtactctga tgttcataca gaaacaatat tgcaacatgt attagctgaa
    16201 tttattggaa atggaggttt agagaagtac atatttagaa tgaagaagtt gtacaataga
    16261 aaacgtaagt acctcataaa agttttaaac acggaattta aaaatgaatt taaaataaaa
    16321 ggtgaagcag cagggcttca tatagttgct catttctata atgttaaatt tacggaaagt
    16381 ttaattcata aaatttttga agcaggtata aaagtttatc ctatacaaca atatgcaatt
    16441 gagaatatat tagaatatga ctatgaaatt atactaggtt atgctcatct tagttttgat
    16501 gaaattgaaa aaggtgtaaa aatactcagc aaaataatac atatgaatca aggtacatag
    16561 ataaaacatg tagcaatcta catataatag atgtaattaa gtttaaactt taaaagaaat
    16621 atatattaat atttttgtat aaaaatacct gatatttttt tatcgatact ttattgctat
    16681 acactaaatt aagatagcaa tttatattaa gaaaaaactt tttgcatagg ttataatact
    16741 taaaaggaga ggatagagtt gaaaacaaat acagatgtta ttatggagat aattgattat
    16801 atagaagaaa atcttacaga aaatctaaat ttagataaaa tagcttatat tgctaattat
    16861 tcaaaatacc atttacacag aatgtttaca aatgttgtag gatgtactat ccatcaatac
    16921 atacagagga ggagacttac tgaagcagct agacaactta tatttacaga caaatatatt
    16981 atagacatag ctattacagt aggatattct acacatcaat cttttacact agcatttaga
    17041 aatttatata aagaatctcc acaagtatat agaaataaag atgaatttta tcctattcaa
    17101 cagagatttg ttttaaatct aaatcatcaa attcaaagtg aaaaatgtat ttcttatgca
    17161 aatatgaatt ataaacaaag aagagatgaa atcaattctt atctgaactt taatattaat
    17221 tgtgaggtga aagtagcatg agtttagtgc cacatgtaat tgaacaaaca ggtcaagggg
    17281 aaaggtctta tgatatatat tcaaaattat taaaagatag aattatattt ataggagaag
    17341 aaattaatga tgctattgca agtttagtag tagctcaatt actgttttta gaatcagaag
    17401 acccagattc agatataatt atatatataa atagccctgg tggctctgct acatcaggat
    17461 ttgctatata tgatactatg aattatgtca gatgtgatgt atcgactatt tgtattggta
    17521 tggctgcaag catgagtgct tttttacttg caggaggaac acatggaaaa agatgtgctt
    17581 tacccaattc agagattatg attcatcagc caatgggagg agctaaaggt caagcaacag
    17641 atgtaaaaat agctgtagat aatatattga aaataaaaga acgattagat aaaattcttt
    17701 ctgaaaatac aggtaaatca atagaagata ttaggagaga tacagataga gataatttta
    17761 tgactgcact agaggctaaa gagtacgggc tgattgatta tataatgaat aggaatgaat
    17821 aaagtatcaa agtatcatat taaaatgtct gttttacaaa tatatatata atattaaata
    17881 agagtgtctc aaaatgaact ttttagttta tgggacactc ttttttgtat gaaattaaat
    17941 atggttttat catttcgaca attattacca aatttcaagt ttaataaatt ctactataaa
    18001 aaatacataa aagataaggt tctttagtaa ctttctgtcg tcaaaagttt ttataaattt
    18061 aataacaaaa caagagaaaa taccatatat tacttatgtc tgcaatatat agaagacaaa
    18121 ggagttgtac attatgatta caataagttt gtgcatgatt gttaagaatg aggaagaagt
    18181 tataggcaga tgcttagaat gtgtaaagga tatagtagac gaaattataa ttgtagatac
    18241 cggttctaca gattccacaa aagaaatagt ctcaaaatat acagacatgg tgtacgattt
    18301 cgaatggata gatgatttct ctgctgcaag aaatttttca ttttctaaag cttctaaaga
    18361 ctatactatg tggcttgatg cagatgacat aattttagaa gctgatagag aaaaattatt
    18421 aaagattaaa gaaagcttgg atacttccat tgatattgtt atggcaaaat acaatgtatc
    18481 ctttgatgaa aatggtaacc caactctctc atattataga gaacgattgt ttaaaagaag
    18541 ttctaatcat aaatgggttg accctattca tgaagtagta cctctttttg gagaggtatt
    18601 ttattctgac attgcaatat ctcataaaaa gcttcataga caggaccctc taagaaatct
    18661 tagaattttt gaaaaaatga tttcagaagg aaaaacattg gagccaagac accaattcta
    18721 ttattctaga gagttgtact ataatgctag gtataaagaa gcaatagaag gttttactaa
    18781 gtttttagac tcatcaagag gatggattga ggattgtatc agtgcttgca gagatttagc
    18841 cacatgttat tacttaatta atgatgaaaa aagtgcctta tattcattgt ttagaagttt
    18901 cgaatttgat gagccaagag cagaaatttg ttgtgacata ggaaagcata tgtttgatag
    18961 acaaaaatat aaagaagcca ttttttggta taaggtagca ttaacaagag ataagaatga
    19021 tactgatgga ggctttaagt cagatgattg ttatggatat ataccatcta tacaattaag
    19081 tgtctgttat gacaggttag gagaatcaga taaagctatt tattatcatg aaaaaacaaa
    19141 agaaatcaaa cctaatgata gtgctgtttt gcacaatgaa aattatttta gtaaatttaa
    19201 aaatagttga tgggtcacaa tcatactaaa tttgacatat tatatataga gcttaaaagc
    19261 tcaaatatat caggaggtgc ttttaataat gagtagaaat aaatattttg gaccatttga
    19321 tgataatgat tacaacaatg gctatgataa atatgatgat tgtaacaatg gtcgtgatga
    19381 ttataatagc tgtgattgcc atcattgctg tccaccatca tgtgtaggtc caacaggccc
    19441 aatgggtcca agaggtagaa ccggcccaac aggtccaacg ggtccaacag gtccaggtgt
    19501 aggggcaaca ggcccaacag gaccaaccgg tccgactggt ccaacaggaa atacagggaa
    19561 tacaggagca acaggattaa gaggtccaac aggagcaaca ggggcaacag gcccaacagg
    19621 agcgacagga gctataggat ttggagtaac aggtccaaca ggcccaacag gagcgacagg
    19681 agcaacagga gcagatggag taacaggtcc aacaggtcca acgggagcaa caggagcaga
    19741 tggaataaca ggtccaacag gagcaacagg ggcaacagga tttggagtaa caggtccaac
    19801 aggcccaaca ggagcaacag gagtaggagt aacaggagca acaggattaa taggtccaac
    19861 aggagcaaca ggaacacctg gagcgacagg cccaacagga gcagtaggag caacaggaat
    19921 aggaataaca ggtccaacag gtccaacagg agcaacagga gcagacggag caacaggagt
    19981 aacaggtcca acaggggcaa caggggcaac aggagcagat ggagtaacag gtccaacagg
    20041 ggcaacagga gcaacaggat ttggagtgac aggcccaaca ggtccaacag gagcaacagg
    20101 aataggaata acaggagcaa cagggttaat aggtccaacc ggagcaacgg gagcaacagg
    20161 agcaacaggc ccaacaggag taacaggggc aacaggagca gcaggactaa taggaccaac
    20221 cggggcaaca ggagcaaccg gagcagatgg agcaaccgga gcgacagggg caacaggagc
    20281 aacaggtcca acaggagcag atggattagt aggtccaaca ggagcaacag gagcaacagg
    20341 agcagatgga ttagtaggcc caacaggtcc aacaggggca acaggagtag gaataacagg
    20401 agcaacagga gcaacaggag cgacaggtcc aacaggggca gatggattag taggtccaac
    20461 aggagcgacg ggagcaacag gagcagatgg agtagcaggt ccaacaggag caacaggagc
    20521 aacaggaaat acaggagcag atggagcaac aggtccaaca ggggcaacag gtccaacagg
    20581 agcagacgga ttagtaggtc caacaggagc aacaggagca acaggattag caggagcaac
    20641 aggagcaaca ggcccaatag gagcaacagg tccaacagga gcagatggag caacaggggc
    20701 aacaggagca acaggtccaa caggggcaga tggattagta ggtccaacag gagcaaccgg
    20761 agcaaccgga gcgaccggag caacaggtcc aacaggagca acaggagcaa caggagcaac
    20821 aggtccaaca ggtgctagtg caataatacc ttttgcatca ggtataccac tatcacttac
    20881 aactatagct ggaggattag taggtacacc aggttttgtt ggctttggta gttcagctcc
    20941 aggattaagt atagttggtg gagtaataga ccttacaaac gcagcaggaa cattgactaa
    21001 ctttgcattt tcaatgccaa gagctggaac aataacatct atttcagcat acttcagtac
    21061 aacagcagca ctttcacttg ttggctcaac agttacaatt acagcaacac tttaccaatc
    21121 tactgcacca aataactcat ttacagctgt accaggagcg acagttacac tagctccacc
    21181 acttacagga atattatcag ttggttcaat ttctagtgga attgtaacag gattaaatat
    21241 agcagcaaca gcagaaactc gattcttact agtatttact gcaacagctt caggtctttc
    21301 attagttaat actgtagcag gatatgcaag tgcaggaatt gcaataaatt agattagata
    21361 agaaaaggct tctaatatcg tattgatatt aggagctttt ttaagaatga ttgatgaaca
    21421 tagttttaat attaattagt gcgcatatta taaaatacta ttatataata taaaataata
    21481 acattaaatt ggaaatatag aattatctag gggtgatact atgaaaaata agattgaaat
    21541 atcaatgaac aactttgtaa aaaattatca taaatcaaat aatataacta caaagtggca
    21601 agaacttttg tttgcttatg catctgctga agatgatatg tttcagaagc taaaaagtgt
    21661 tgtaggaaca tctcatgcta tgccaaaaga ttttctggaa aatggaaaaa ctataattac
    21721 atattttata ccttttgatg aaagtgtaaa taatagtaat attggagggt ttgaatgttc
    21781 tgaaatatgg gcaagagcgt acatagaaac taatatgttg atttcaaatt taaatgattt
    21841 cttatgtgaa gaactagaga agatgggggc taattcatat gctattcctg ggtcgtataa
    21901 ttttgacagt gaaaaattgg taagtgactg gtcacaaaga catgtagcat tcatagcagg
    21961 tcttggaact tttggtttaa ataatatgct tattacagaa aaagggtgtt gtggaagaat
    22021 aggaagcata atcacaagtt tagaattaga gccaactaaa agaccagaaa atgaatactg
    22081 cttgtataaa cataataata gttgcaaaaa atgtgtcaac aaatgcgtga aagaagcttt
    22141 aaaagaagat ggatttaata ggaataagtg ttatgaaatg tgtatgataa atgaaaaaaa
    22201 atacacttat ataggtggat gtgatatttg tggaaagtgt atagttggag ttccttgttc
    22261 agtaataaac ccatcaagat aatggattta agttgactaa taattttaaa gatagtttat
    22321 aatgaaaaaa ttttagttat caaaataaat ataatataaa aactaaataa atgtgtttaa
    22381 aaaatggata aataatttgt gttgattgac aaccagttat actgttgata gacttatatg
    22441 tatcgctgtg atatataagg agggttgaga ttttatgttt gatttaatct ttatttttgc
    22501 atagcaaggg ctattgcaac tatgaaattt aatatataaa tagccctttg ctattcctaa
    22561 tgaaaaatta ctatttaata ggagagcaaa atgagctata aaaaagcaat acatatatta
    22621 ccagaagaat tacttgaatt aatacaggaa tatgtagatg gtgaatgtat ctatattcct
    22681 agaaaatcta ataataaaaa agaatgggga agtaatacac ctactcgtga ggagttgtca
    22741 attagaaata tgcagattta cgaagactat caagttggat atgatttgca atatttatcg
    22801 gaaaagtatt atttatcttt gaaaagtatc caaagaattg tattacaaga aaaaagaaaa
    22861 gatatctaag gatgagccag tatagtttta taattatact ggctcatttt cttttgataa
    22921 aagtgtttga ggtatagttt cttttaagtg gatgatataa tttaagtaat ttcaataact
    22981 tatacagtag ctaacaaagc tggttgtaaa gtatctaata agaagtagta gctttttata
    23041 tgtttgaaat taaaatttat taaaattagg aggtcttgtt ttgaaaaaaa tacttgatta
    23101 tattccacct tttcataact ttctattaat ttagtaatct tatagaaagg aaattgcatt
    23161 tatgaaaaaa attacttggg aggtggaata tatctcccag ttacctgtaa ttaggtattg
    23221 taaaaaatgt ggaaaaaaga ctgaatatat ttgttcaggt ttatttaggg ttaatgctca
    23281 acataaatat ttggatatat ggttaatata caagtgttca aattgtgatt caacatggaa
    23341 ctcaactata tattctcgtg ttaatccaaa aagcttaaat ccagaaatac tagaacaatt
    23401 ccatacaaac gattataatc ttgttaagca atatgctatg aatatggaac ttttacatag
    23461 aaatggagca gaagttggta ttccagagta taaaatagta ggacaagaaa ttaatattaa
    23521 tgaccttaca caagttcata ttattagtaa atatccatgt cagttaaagg tatcaacatt
    23581 attacgtgag aaactaggtt tatctaggaa ggtatttgac gaaatgttgg attgtgggat
    23641 tattagaagt aactcaggag ttgatttaaa gaaaggtaaa ttaaattatg aaattatgtt
    23701 agatataggc aaggagaagc aaaagtcttc aaattgatta gaataactaa cttaatatat
    23761 tttcaggaac atcatttaaa aaaatagtgg ctttaaaaaa tttaaagcca ctatttttta
    23821 atatgtttta tattaatatt taaaatatag tgtgtattct tcaaaattat agcgataatt
    23881 aaaatattac tataaaaagg aaggtgcata cttttta
//
LOCUS       DAEHWO010000058        23290 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEHWO010000058 DAEHWO010000000
VERSION     DAEHWO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23290
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.058"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            230..619
                     /locus_tag="KNP54_002711"
     CDS             230..619
                     /locus_tag="KNP54_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0893584.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            939..1448
                     /gene="vanZ1"
                     /locus_tag="KNP54_002712"
     CDS             939..1448
                     /gene="vanZ1"
                     /locus_tag="KNP54_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HBF0893585.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LIPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLVFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1550..1744)
                     /locus_tag="KNP54_002713"
     CDS             complement(1550..1744)
                     /locus_tag="KNP54_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBF0893586.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(2260..2652)
                     /locus_tag="KNP54_002714"
     CDS             complement(2260..2652)
                     /locus_tag="KNP54_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0893587.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            3219..3581
                     /locus_tag="KNP54_002715"
     CDS             3219..3581
                     /locus_tag="KNP54_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893588.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            3565..4290
                     /locus_tag="KNP54_002716"
     CDS             3565..4290
                     /locus_tag="KNP54_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893589.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEDEEYEEELKQN
                     IIENIKKNFDEKNLVQVYKYRGV"
     gene            4310..4729
                     /locus_tag="KNP54_002717"
     CDS             4310..4729
                     /locus_tag="KNP54_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893590.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            4719..5243
                     /locus_tag="KNP54_002718"
     CDS             4719..5243
                     /locus_tag="KNP54_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893591.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            5555..6112
                     /gene="efp"
                     /locus_tag="KNP54_002719"
     CDS             5555..6112
                     /gene="efp"
                     /locus_tag="KNP54_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBF0893592.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            6204..6659
                     /locus_tag="KNP54_002720"
     CDS             6204..6659
                     /locus_tag="KNP54_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBF0893593.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            6822..7532
                     /locus_tag="KNP54_002721"
     CDS             6822..7532
                     /locus_tag="KNP54_002721"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBF0893594.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            7586..8656
                     /locus_tag="KNP54_002722"
     CDS             7586..8656
                     /locus_tag="KNP54_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0893595.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            8684..12238
                     /gene="smc"
                     /locus_tag="KNP54_002723"
     CDS             8684..12238
                     /gene="smc"
                     /locus_tag="KNP54_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBF0893596.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKFAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            12265..13545
                     /gene="ftsY"
                     /locus_tag="KNP54_002724"
     CDS             12265..13545
                     /gene="ftsY"
                     /locus_tag="KNP54_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBF0893597.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDIEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            13648..14016
                     /locus_tag="KNP54_002725"
     CDS             13648..14016
                     /locus_tag="KNP54_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBF0893598.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            14013..15365
                     /gene="ffh"
                     /locus_tag="KNP54_002726"
     CDS             14013..15365
                     /gene="ffh"
                     /locus_tag="KNP54_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBF0893599.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPINIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            15403..15675
                     /gene="rpsP"
                     /locus_tag="KNP54_002727"
     CDS             15403..15675
                     /gene="rpsP"
                     /locus_tag="KNP54_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBF0893600.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            15740..15967
                     /locus_tag="KNP54_002728"
     CDS             15740..15967
                     /locus_tag="KNP54_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBF0893601.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            16075..16590
                     /gene="rimM"
                     /locus_tag="KNP54_002729"
     CDS             16075..16590
                     /gene="rimM"
                     /locus_tag="KNP54_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBF0893602.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            16599..17294
                     /gene="trmD"
                     /locus_tag="KNP54_002730"
     CDS             16599..17294
                     /gene="trmD"
                     /locus_tag="KNP54_002730"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBF0893603.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            17479..17829
                     /gene="rplS"
                     /locus_tag="KNP54_002731"
     CDS             17479..17829
                     /gene="rplS"
                     /locus_tag="KNP54_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBF0893604.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            18150..19046
                     /gene="ylqF"
                     /locus_tag="KNP54_002732"
     CDS             18150..19046
                     /gene="ylqF"
                     /locus_tag="KNP54_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBF0893605.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            19435..20727
                     /gene="brnQ"
                     /locus_tag="KNP54_002733"
     CDS             19435..20727
                     /gene="brnQ"
                     /locus_tag="KNP54_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBF0893606.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLFVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
     gene            21846..23138
                     /gene="brnQ"
                     /locus_tag="KNP54_002734"
     CDS             21846..23138
                     /gene="brnQ"
                     /locus_tag="KNP54_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBF0893607.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT         9730 a         2203 c         4140 g         7217 t
ORIGIN      
        1 ataaaacgaa ctaaaattat cacactaaag cataaaacat actctaatca tgttagataa
       61 atttttgaat atataatcca aaagtactct ctaaagtaga gtacttcttt tttattaatt
      121 atttttatat agaataaatt ggaatttata tttattccaa tctaattgat tacatacact
      181 tattgttata aagtttagtt atacataaat tggtaagagg tgtaaactaa tgaagattaa
      241 taaattacca catgcagaac taaaactaat gaagtatatt tggggagtag atgatgtatt
      301 agcctcaaga gatatcatag aagacatgaa gttgaaatac gattggaaaa agagcacaac
      361 attgacattt ttaaaaaatt tagtagataa gggcttttta actactgata aggtagatag
      421 atgtacgcat tatactatag ctataaaaga gaaagattac ttaaaagttg agacaaagag
      481 tttttttagt tttatgcata acaattcatt taagagtttt atttcagcac tacatgatga
      541 tgaagtttta gatagtaaga gcttggacaa attagaagaa tactttaaaa atttgaaaga
      601 agaagatatt gatgactaat aaagctatca gtatcttttt agtttgagac aattgagagt
      661 agcgtttgga tttaatgtta gttttatgtg atggtagaac attatataaa gaaaagtgat
      721 tatttcctta gtgtttgata gtaaaaaata tagagaataa taccaattaa aatttaaaga
      781 tatatgaaat actacaatag cttaaatcat gtaaatatga taaagatatt gaaattataa
      841 aaggaatata attttagaag aaatagttga cagataaatt accttactat attattgtat
      901 taataaaata atacaataat atagtaagga ggtaataaat gaaatctaga aaacataata
      961 ttacaaaagg attatttata gtttacataa ttattttaac atggataata ctatttaagt
     1021 tgcaatttga tatctcatct cttgaaacca tgaatcttag aagcataaac ttaatacctt
     1081 ttgctgggtc acttataatt aataatagag tagatatatc agagattata ttaaatgtgg
     1141 ctatatttgt accatttggg atatatgtgt gtatgctaaa agaagaatgg agctttataa
     1201 aaaaagttat acctattttt ataactagtt tggtatttga aacacttcaa tatatatttg
     1261 cactaggtgc aagtgatata acggatttga taggaaacac actaggagga atcataggaa
     1321 tagctgtttt tatgctatta tcgaaaatat ttaagaataa taccataaaa attatcaatg
     1381 tattggcatt gattgtgaca attattgttg tattattttt aggattagtt atttttgcaa
     1441 acttatagaa ataagtatat atgtttagct taaaatagaa cgtaagatac agttacatat
     1501 aaaattattt acacataaaa agcacctata caggtgcttt cctaaattat taaagaatta
     1561 ttgtatcttg aaactcttgt atgttcaatt cttgattttc tcttgttttt tctaataaat
     1621 ctaacgcaca atttatacaa actttaattt ctgcattggt atttttctca taataagtta
     1681 tatatttatt tctatattta tctatttctt ttccacaacg actacacatt acaattacgc
     1741 tcatatctta gttcctccat ctctaattat tcttaatata ttcaatagta tcacttttct
     1801 gaaaataatg attgttaaaa ctgtatcaaa tttagattta ctttttatta taatgcattt
     1861 taataaaaaa ataaaggtta tgggtaaaat atttatagaa aaaagtatat tattgaatag
     1921 attataaaat tttattattt tttagcagtg ttaaatacac attaatatct ataaagtgac
     1981 aaaataaaaa atactattta aatagatatt aaaaaattga taccaagtat ttatttgcta
     2041 tatgaataac aatttattta ggaactttac tttaacactg tataataata aagtaattgc
     2101 taaaaacgtt tgatgatttg gatgtatttt tagaaattag aaaaatatat acttactgac
     2161 taatgataat cttatatgta ttttagtttg agtgatttaa gaaaagtgtt ttgaatgggg
     2221 attattttat agagtaaata aatatataat agtagaaaat tacatataaa gagtagtgtt
     2281 tatttcatta ccttctttat ctgttccgat agggtcttgt agagatactt gagttttatt
     2341 ttttttgtta gatctaatat tcattaaaat ctcattttca atacatctag aagcatatgt
     2401 tgctaatcga gttcctttat ctatgttata agtttctata gctttaatta atcctattgt
     2461 acctatggat attaaatcat cctgatcttc cgttgaatta ttatatttct ttgctatata
     2521 agctactaat ctcatgtttc tttcaattaa tgtatctttt gcacttttat cgttttctat
     2581 tttaaattta gttaaatact caatctcttc ttcaggggtt aagggttttt caaaagattt
     2641 aagagctgcc aataggtcac ccccttttca acggtcactt taaattatat gaaggagact
     2701 tatccaagtt gactgttatc taataaaata atatgcatat ttttagaatt taaaacatat
     2761 atttgcaaac ttttgaatgg aatatgacat aaagagtggg aatttaaatt taagtttttg
     2821 ttgtatatat atgaaataag gcgaagaaat tattgattta taaagtataa attggaattg
     2881 aggtgtcaat aaatataaaa ggaaatagta tttatatatg ttttggtgtt gaagtaaaag
     2941 attaatgcaa agcattagag tctataaaaa tatgaatata ggaggtgtaa ttttacaata
     3001 cttaaaaaag taaatgtaat taattgtttg tataaagttg attacaagca aaagtatcag
     3061 tcatagttaa tactgttaag ggtgaaggtg gtgtgttaat ttatatatgt atgggaagaa
     3121 attttgatta caatgaaaaa acttacaaaa gatatttatg aaaaaactta tagttaaatg
     3181 tttatatata aaatattatt taggggttgt ttttattatt gaaaataaga aagagtggtt
     3241 ttatatcaat tgaatgtata ataagtattg ctatattata tgtggctgtt tatttagttt
     3301 ctacatcatt gtataattgt tatagtttta tcagtagaaa tatatctgac agagaaatgt
     3361 taagtacagc aaaaaaatat atagaagatg agaagtatag aatacaaaat agtaagtatg
     3421 agttaattga agataagata gaaaaaaatt acataaatgg atatgaaatt aacagtaaaa
     3481 tagagcaaat tttagattat tatcaatgct atgaaataaa tatagagata aaaaatgaat
     3541 ttaaaaaact gaggtttaat agctatgtta ctagaaaata aaggctctat attaataata
     3601 acattgataa tattttctat tataagtact gtgtgcatta tgtgtatagg tttaatttat
     3661 acacataata atatgtttga gttaggatac aaggacattc aactaaaaga aatttcttta
     3721 agtggaatag aaatatcagt aagtaatgta ctttcttgtg ttgaggaagc tattgatgta
     3781 tctaataatg aagacgaatt tagagaatat ttcttaggaa ataatatgat tgaatgtata
     3841 aaaaaaataa aagatacatc ttatagtagt ttagaagaac tttctttaaa agtagaaaat
     3901 aatactattt atgacagagg agattttttt gaatttgata tagaaagtaa tgttagagaa
     3961 aaagaatttt taaaagcaat aaaagtaaga gtgaaaatca aaaatccatg gataggaatt
     4021 gacattgaag attatatgga taaatctaat aacaataaaa ttgatgacaa aacattcaat
     4081 aattataaag catctgaaaa taatgaaatt ctaaatcaat ttaaaaatga aagtgaaaat
     4141 ataaggaatc aagaggttgg tggatttaca gaagaagatg aagaagatga agaatatgaa
     4201 gaagaactta aacaaaacat aattgaaaat ataaagaaga attttgatga aaaaaaccta
     4261 gtacaggtat ataagtatag gggtgtataa ctttgaaaaa agaaggaatg tgactgtaat
     4321 agaattaata gtatctatca gtataatact cttgatagtt acattatctt ttccaaaaga
     4381 taatcttgaa aatcataaaa taaatttatt tgcacgtcaa ctttgttcag atataaggta
     4441 tgttaggcga attaatatgt ttagcaacta caatacatat atatattata taaatcaagg
     4501 taaacacgaa ggttatgtat tgagaaaaga tggtaaaaac attaaatcaa taatgctacc
     4561 taaaaatgca aaaatagcta ggagtattga aataataaag tttaaatctg atgggtcgcc
     4621 tcaaaaggcg tctacaatag agatatataa taatagatta agaaaaacta taacaataac
     4681 acctgtaagt ggaagagtac ttctgaaaga gggaaaatat gaaacataaa tatggttact
     4741 tgcttttgga aagtgtcgta tcattgtctt caatggtgat aattatacta gttttatatt
     4801 ctatattttt gtctacaata aacttaaagt taaaagtaga agataagata gaactacaac
     4861 aacaaagtct tgaaatcata aaatctatgg aaggaattat tagcaattct atgggaataa
     4921 tgaatgtatc taattatgaa gaaacattta aaaagacaac atctataaaa tgtagatatt
     4981 tagatgaaaa taataatgaa gaaggcataa gtaataaaga aattatattg aatgaaagac
     5041 gaaataagtt atttgtaaat tctttaaatg gcgaaagtag tcaagcaggt ggttatgaaa
     5101 ttggagatta tgtagatgag atgtatgtat caattactaa taatggtcaa tatgttaata
     5161 ttaaattgaa attatcaaaa cgtagtcaaa aatatgagac tgatttcaaa ataaaagtat
     5221 ggaattttag tgaaagtata tagaaataca taaatttaag agaaagaagt gacatcaata
     5281 agtcatataa aatataatta ttgagaacta tataactaaa taatatcaat atgtaaagtg
     5341 tatagattaa gaatatagag gataataata aaaatataga ataagtaatt tgccaaatac
     5401 ttgtttatat tgtataactt atgatattat gatattagta aaaatttgta atcctgactt
     5461 gacagaattc aagtaagaga tataatttta aaggcatagt aatgtaaaat ttactaaaaa
     5521 ataagaaatt tattttaata tggaggaaca aaaaatggta tcagcaggtg attttagaaa
     5581 aggtgttaca tttgaaaaag atggacaacc atgtttagta gttgattttc aacacgttaa
     5641 gccaggtaaa ggagctgctt tcgttagaac taaatacaaa aacttaaaaa caggagctat
     5701 aagagaagaa agtttcaatc caagtgaaaa attccctaaa gctgttatag atacaagaca
     5761 aatgcaatat ctatacaatg atggtgagtt atattatttt atggatcaag aaaattttga
     5821 acaaatacca ttaaactatg agcaagttga agatgcaatt aagttcttaa aagaaaatga
     5881 agttgctaca ataagatttt accaaggaca accattccaa gtggaagcgc caaactttgc
     5941 agagctagaa gttacagata cagagccagg tataaaaggt gatacagcaa gtaatgtaac
     6001 taaagcagct acagttgaaa ctggagcagt tgttcaagtt ccattattta taaatactgg
     6061 agataaagta aagatagata ctagaacagg tgaatattta tcaagagtat aaaaatttat
     6121 gtatataaaa gcttatatgt cttaataata taagatatat gagcttttag tttatatata
     6181 aaaaagaaag cgaggggtgt tacatgaaac atttatatga agaagttgca tacttaaaag
     6241 gcctagcaga aggactagaa ataagtgctg aaagtaaaga agggaaaatg atacataaaa
     6301 tagttgatgc attagaagta tttgcagatg ctattgtaac attggatgaa gaacaagaag
     6361 aacttcaaga ttttgttgaa tctatagatg aagatttagc agatttagaa gaagatattg
     6421 ctgacatgga agaagatctt tatgaagaag atgacgatga ggatgatgag gacttcagct
     6481 atatagaaat ggaatgccca aattgtggag agttagtaga aatagacgaa gatttgttat
     6541 atgatgatga agtagatgtt gtttgtcctg attgtaaggc tgtgatatta tcatcagaag
     6601 atgattgtga tgatgattgt acatgtggtg gttgttcaag ttgtgatgat agagagtaaa
     6661 aattcataag aattaaaact gcctatgatg cctatgagat attttgcttc ataggtagtt
     6721 ttatttttat gaggaagggt attatgtatt ttggttttgc aatacttgga caaaaatagt
     6781 acactagaat ttatagaata ggattttgga gggatgtaaa tatgaaaata agtaaaaaat
     6841 tactagataa tatacaaaga tttgaaaatg ttataaatta taaatttaaa aataaagaat
     6901 atatactaga agctcttact catagttcat attctaatga aaataaaaaa tataatttta
     6961 acgaaagatt ggaattttta ggggattcgg ttttaggcat agtgataagt gattatttat
     7021 ttaatgaaga agctaatctg cccgaagggg aactaactaa acttagagca aatatagttt
     7081 gtgaagattc attaagtgaa gtagctaatg atataaattt aggtattcac atgttattag
     7141 gtagaggaga agaagcaaca ggaggaagac ataggacttc aatattagca gacgcatttg
     7201 aagctgtaat agctgctata tatcttgatg gaggttttga aagtgcaaga cagtttatac
     7261 ttcatcatat ggaaaatata atttatgatt caagaaaagg aaatatattt agagactaca
     7321 aaacgcatct tcaagaggtg ttacaaggga atggagaaaa taatatctgg tacaggctta
     7381 tagaagaaaa aggaccagac cataataaaa gatttgtaat ggaagttgga attaatgacg
     7441 atgtacttgg tataggagaa ggcaagagta aaaaagaagc tgaacagtta gctgctaaaa
     7501 tagctttaaa gaaaaaatta tgggaaaaat aaatataata tgtaaaaata taaaaagaaa
     7561 tatttatatt agaaggatgt tgtagatgaa aaagagaatt atacctatat ttgttcctca
     7621 caaaggatgt cctcatgatt gcatattttg taatcaaaaa aaaataacag gtgtgagtac
     7681 tgatgttact agtgaagatg caagaaatat aattgaggaa tgtttagaga ctatagataa
     7741 agatgcagat gtagaaatag cattttttgg tggtagcttt actgctatag atattgatat
     7801 acaaaaaagt ttattatcag ttgctaaaga atatgtagaa aaaggtcttg taaaagatat
     7861 tagaatgtct acaagaccag attgtattga tgaagatata ttaagtatgt taaaagaata
     7921 taagacaagt ataattgaac taggagtaca atccttagat gaaaaagtat tattagatag
     7981 tataagaggt catcaatctg aaattgtata caagagttca aagatgataa aaaatagtgg
     8041 aatcaaactt ggattacaga tgatgattgg tcttccagct gacacagaag aaaagtgtat
     8101 atttacagca aaaaaatttg tagagctaaa accagattgt gttagagtct atccaacttt
     8161 ggtagtaaaa gatacaggtc ttgaaaagtt aatggaacaa aataaatata atccatttac
     8221 tcttgaagag agtgtaaata tagtaaaaaa agttcttgta ctgttttatg ttaataatat
     8281 caatgtaata agagttgggc ttcaagctac tgatgatata caaattggaa aagctgtttt
     8341 agcaggacca tatcatcctg catttagaga gttggtagaa gcagatatga taaaagatta
     8401 tttagaattt gttattttgc aaaataaaaa tataaagcaa atgttggtca aatctaataa
     8461 aaagaatatt tctaaaatca taggaaataa aaaaacaaat gttaaatata tggaagaaaa
     8521 atttggtgtg cttttaaaaa cacaagaatc agatttagat ataaatcaat tagaaattgt
     8581 gttagatggg aaaagtttaa ttagtgctaa tatgagagac attcatagaa aattgtatga
     8641 catttatgac ctttagtttt aataatgaag ggagagaaaa gatttgtatt taaaaagact
     8701 agagttaaag ggatttaaat cctttccagt aaaaacagat attattttta aagaaggaat
     8761 aacagccata gtaggaccaa atgggagtgg aaaaagtaat atatctgatg ctgtaagatg
     8821 ggtattagga gaacagagta ttaagagtct tagaggtgat aaactcgaag atgtaatatt
     8881 tgcaggtaca gatacaaaaa aacctatgaa ttattgtgaa gtggctctta ctattgataa
     8941 ttctgaaaat caattggaat tagattttac agaagtaact ataagaagaa gggcttatag
     9001 aaatggtgaa agtgaatttt ttctaaataa taaaagttgt agattaaaag atataaaaga
     9061 agtcttttta gatactggta ttggaaaaga tggttattca atcatagaac aaggaaaagt
     9121 agatgaaata ttaagtaata atcctttaag cagaagaaaa gtttttgatg aagcttgtgg
     9181 catatcaaaa tatagatata aaaaacagga agcagaaagg aatttaagta atacaaagga
     9241 aaatttagaa agaatagatg atgtatatat agaaattgaa aatcaattaa agcctctttt
     9301 taatcaacag acaaaggcaa aaaagtactt ggaaataagt gaaaaattaa agacacttga
     9361 agtaaatagc tttataagag aaattgaagg aatagaaaaa gaattaagtg aggttaatga
     9421 acatcgtaag gttattgaaa aggagctcaa tgaaaaagaa gaacaaaaaa atgttgtaga
     9481 gaaaaagcaa gaagatatta ataaagaggt agaggtatta caagatgtaa ttgaaaaatc
     9541 tgtagattat ataaattcaa ttaaaggagt tatatcaaaa aaagagtccc aaataaattt
     9601 aattaaggaa agaataagaa attttacgaa tgaaattagt agaaaaaatt tagaaataaa
     9661 ggatataaaa gagaagctaa atgaaaataa gcaatacata aaagaattag aaagcaataa
     9721 attatcaggt agtgaagaac tatctacctt gcaggaaaat ataaaagtat tggaaggaag
     9781 taaagataaa caaaaaatta agttagaatc cctaaataat gagatagaat tattgaaaga
     9841 aagtataatt gatatattaa ataagaaaca agagtttagt aataagctgt ctactttaaa
     9901 cgcaaataaa gaaaatatga atatcagaga tgaaaatata aattcagaga taacagagtt
     9961 aaacaaaaat attgaaataa aatcatctga attagatact ataaataaag aatttaatat
    10021 gcaaaatgaa aatttaaaga atgtaaataa tagacataaa gaattatcaa ttaatttgca
    10081 ggattcaatt agtgaacaca ataaactaga agatgaaata cagaaaagta aatataattt
    10141 aaatggatat aattcaaagt taaatgtcta tatagatatg gaaaatcatt atgaaggatt
    10201 taatagagga gtaaaagaag tactaaaaaa taaaaattta aaaggagttc atggagcatt
    10261 aggacagatt ataaatgtac ctgaaaagta tgagaaatct atagaagcag ctcttggtgc
    10321 ttatatgcaa aatataataa ctgataatga gtttagtgct aagtttgcaa taaactatct
    10381 aaaacagaat aatttaggta gagtaacatt tcttccatta aatataatta aatcaaataa
    10441 aataagtcta ggaaatttaa aagcaaatac taagttcata ggaatagcaa gtgatttaat
    10501 tacatttgat gaaaagtata gaaatataat tgaaaatata cttggaagaa caatacttat
    10561 aaataatata gatgagggca taaaatttgc aaaagaaact ggtcataggt ttaaaatagt
    10621 aactttagat ggtgaaatct taaatccagg aggttctttg actgggggaa gtctaaaaac
    10681 taatgggaat atactatcga gaaaaagata cattaatgaa tatacagaaa agataagtaa
    10741 tatcaagaat gaaatttcac atctagaatt aaaaagagaa tctttagaca aagatgtgaa
    10801 aaatatcaaa aatgaaattg attcacatga aagtaaaata aaagatttag aaaaaagtat
    10861 aataataaaa agtacaagta taaagaatgt tgagtctgaa attgaatcgt taaaaggtag
    10921 tattactaaa ttagaaaatg agaagaatga tttaaattct aacctaaatt atacacttga
    10981 aaaaagtgat gatgttagaa aagatatgga agagttagat gatttataca ataaaaataa
    11041 agaaaaaatt gatgcattga atgaggaaat aaaaagatac aatgatttat atgataaaga
    11101 aaaatctgaa tttgatgaat tgaacttaag tttagtgaag aaaacagaag tttacaatag
    11161 tatagttaga gatataaaaa gaatatctgg tgaaaattgt gagctagaag aaaaaaataa
    11221 acaattagaa gagtcattaa attatgaaga acatgaaata attaaattac aagattctat
    11281 actcactgaa gaaaaagaaa aagaaaattt aacaaaacaa ctaggggata gtaatagaaa
    11341 tcttgaaact agaaaaatag caaaagatga tttaaaaaat agttttgatg aaattaataa
    11401 agaattaaaa actatagata gacagcatat agaacttaaa gaaagtttat ttaaagttgg
    11461 tggaagatta gaaagattaa aaactagtca agacacatat ataaataagt tgtttgagca
    11521 atatgatatg accttagtac aagcattgga aattaaagat gaagatttgg atatagatag
    11581 aaaattctta gaaagtctaa agagagaaat aagaagtctt ggaaatataa atatagactc
    11641 tataaaggaa tatgaggaaa taaaagaaag atacgatttt tatagcgaac aaaagcaaga
    11701 tttagaagag tctatggaag agatagaaaa acttatacat actttagaag aaaatatgaa
    11761 atctgaattt gaaattaagt ttgaagaaat aagtaaaaat tttaaatatg tatataagag
    11821 attatttggt ggaggttgtg gagaattaac tattttagat aaagaaaatt tattagaaag
    11881 tgatatacta ataacagctc aacccccagg taaaaaaatg aaaaatttaa acctattatc
    11941 tggtggagag aaagctttaa cggcaataag tatattattt gctatattga ttacaaagcc
    12001 aacaccattt tgtatattag atgagattga agcgccactt gatgacgcaa atatatttag
    12061 atttggagaa tttttgaagg atttatctaa agagactcaa tttatatcag taactcatag
    12121 gagaggaaca atggaagctg ctgattatat ctacggagtt acaatgcaag aaaaagccat
    12181 ttcaaaagtt attagtttaa aattaaaaga agctcaggaa ataacagata ttatataact
    12241 tagattgaca taggaggaat aacagtgtta aaaaaattat ttggttttgg aaaagacaag
    12301 gaaaaggaaa tagaaaaaaa agatgctgaa gaagaaatag aagttgaaga cagtgttgat
    12361 aatttagaaa acttggaaga aactattttt tcaggacttg aagaagaagt gatagataaa
    12421 gtggaagata ttgaagaaaa aaatgaggaa agtgtcaata atgaaggcac tgaagaaatc
    12481 gaaaactttg aaaaaataga agttgagatg gatagtaatg gaaaagaagt agaaaatatt
    12541 tcaaataatg attctcaaga agagataatc gaagaattag aaaattatga tgaaattgag
    12601 tctaaagaga tagaagataa agaagataag aaagttaact tgtttgaaag actaaaacaa
    12661 ggattgacaa aagcaaagca aggaataact gatagaatag atgaagtttt aaaatcatat
    12721 acaaaaatag atgaagaatt acttgaagat ttagaggaaa ttttaataac agcagatgtt
    12781 ggtgtaaata caactatgga tataattgaa agactaagag ataaaataaa gcaaaaaggt
    12841 attactgaac caataaaggt aagagaagaa cttaaatcta tagttgaaga tattcttaca
    12901 aatgaaaact ctacactaga tatagaacca gcaccatgta taatattaat ggtgggtgta
    12961 aatggggtcg gtaagactac tacaataggt aaactagcaa atagatacaa aaaagatggt
    13021 aaaaaagttt tattagcagc agcagataca tttagagcag cagcgacaga gcaattagaa
    13081 atttgggcaa atagaaccaa tgtagacata ataaaacatc aagagggagc agaccctgga
    13141 gctgtagtat ttgatgctat aaaagctgca aaagctagaa aaacagatgt attaatatgt
    13201 gatacagcag gaagattaca caataaggct aatcttatga atgaacttgg aaaagtattt
    13261 aaaatagtag atagagaatt tccagaagca aaacgtgaag tacttcttgt ggtggatgct
    13321 acaacaggtc aaaatgcagt tgttcaagca aagacattta aagaagttgc agatataaca
    13381 ggtatagtac ttacaaaact tgatggaact gcaaaaggtg gagtagtcct tgcagtaaaa
    13441 tcagaagtag atgtacctgt aaaacttatt ggagttggag aaagtgtaga agacctacaa
    13501 gatttcaatg caaaatcatt ttcagatgca ttatttggta actaatgttc ttttaaaaat
    13561 aatggttgac aagagtgttg ttatgatata aaatacaata gtgtaaagta aataaccttt
    13621 acagtatact gctaggaagt gtaagatatg aatatagaaa aaatggtcga aattggattg
    13681 ttatttgaac agtataaaga attattaact gacaagcaga aagaaatagt tgctctatac
    13741 tatgaagaag attattcttt aggtgaaatt agtgaaaatc tgaatgtatc aagacaaggt
    13801 gtttatgata ccttaaagcg ttcagaaaaa atactaagag attatgaaga aaagttacac
    13861 ttagtatcaa agattcaaga gcaggaaaaa aatattaaga ttataaaaga taaaattatt
    13921 gacattaaag aagatttatt gcacaataga gattgtgcta atttaatccc taagctagaa
    13981 aatatagaag atgtatgtag ggagatgata aaatgatatt tgaaggattg tctgataaac
    14041 tacaaggggc atttagtaag ttaaaatcta aaggaaaact tacagaagta gatgtaaaaa
    14101 atgctatgag agaagttaaa cttgctcttc ttgaggcaga tgttaacttt aaagtagtta
    14161 aagatttcat aaaaaaagtt caagagagat gtgttgggca agaagttatg caaagcttaa
    14221 ctccagctca gcatgtaatc aaaattgtaa atgaagagct tacaagttta atgggagatg
    14281 tacaaagtaa agtaatgatt tcctcaaagc ctcctacaat tttaatgatg gttggattgc
    14341 aaggtgcagg taagactact acagcaggaa aacttggagg atattttaaa aagcaaggta
    14401 aaaaacctct attagtagct tgtgatattt atagaccagc agctataaag caacttcaag
    14461 ttgttggaga aaaattggat atacctgtat tcaatatggg agataaagaa aatccaataa
    14521 atattgcgaa agcaggttta agccatgcga ttaaaaatgc taatgattta gttattatag
    14581 atacagctgg tagacttcat atagatgaag tacttatgga tgagttaaag tctattaaat
    14641 cagaagttaa gccacatgag atacttttgg ttgtagattc tatgacaggt caagatgctg
    14701 taaatgttgc agaaagcttc aatgaggcac ttggtgttga tggagtagta ttaactaaat
    14761 tggatggaga tactagaggt ggtgctgcgc tttcaataag agcagttaca caaaagccta
    14821 taaaatttat ggggatggga gaaaagctag atgatataga acctttccac ccagatagaa
    14881 tggcatcaag aatattaggt atgggagatg tcttaagttt aatagaaaaa gcacaagaaa
    14941 atatagactt agagaaagct aaagaattag agcaaaaaat taaaaaacaa gagcttgatt
    15001 ttgaagattt cttacaacaa atggaacaaa tacaaaatat gggacctctt gacaagatac
    15061 ttggtatgat acctggtatg ggaaatgtaa aagaccaact tggagatgta gatttgaatg
    15121 gcaaagaaat gaagagaaca aaagccataa ttcagtcaat gactacatat gagagaagaa
    15181 acccaggagt attaaatgct tcaagaaaga aaagaatagc taaaggcagt ggaactagtg
    15241 tacaagatgt aaatagactt ataaaacaac ttaatgaaat gaaaaaaatg atgaagatgt
    15301 ttgctggttc acaaaagagt atgaagaaaa ggggcggctt aggcggttta ccttttttta
    15361 aataaaatat aaaaaagtaa aaattattcg gaggtgactg taatggcagt taaaataaga
    15421 ttaaaaagaa tgggagctaa caaaaaacct ttctacagaa tagtagtagc tgattcaaga
    15481 gctccaagag atggaaaatt tatagaagaa ataggatact ataatccaat ttctgaacct
    15541 aaacaagtaa gaataaatga tgaaaaagct ataaaatggt tagctactgg tgctcagcca
    15601 acagaagtag ttaaaaaatt acttgtaaaa aacggagtaa tagaaaaatt cgaagcttct
    15661 aaacaagcaa aataattttt tcttggcaat tagtttaagt aagggctcat tgctaaggtt
    15721 actttaggag atgaaatata tgaaagagct agttgtagat atagctaagg ctctagttga
    15781 taatcctgac tcagttgttg ttgaggaatt tgaagataat gatggtatcg tcttaaagct
    15841 tacagttgct caagaggata tgggtaaggt tattgggaag cagggaagaa tagctaaagc
    15901 tataagaact gtcgtaagat ctgttgcaaa tagagaaaat ataaaagttt ctcttgagat
    15961 agtataaaat aggaggatta ggtataatgc ctagtccttt ttatataaat gcgtagttta
    16021 agattttatg atgatatgac cacataagat taaatttttt aagaaggtga taacatgaaa
    16081 gaaaaattaa ctcattttaa ggtaggtcaa atagtaaata cacaaggttt aaaaggtgaa
    16141 gtaagagttt atccgcttac tgatgatata gagaggtttg atgaattaaa agatttctat
    16201 ctgggaaaag atttaaataa taaattggct gttgaaaaag taagatacaa aggttctatg
    16261 gttataatga agataaaagg catagacagc atagagaaag cagaaaaact aaaaaataaa
    16321 tttatgtatg tagctagaga agatagcaga gagcttgaag aaggcgaatt ttttatagca
    16381 gatatgattg gaatggaagt tttaactgta gatggaaaat atgtagggat actagaagat
    16441 gttcttcaat actcagcaaa tgatgtctat gtagtaaaag gtgaggaaga taaagaattt
    16501 atgataccag ctataaaaaa atttgtacct acaatagata ttgatgaaag aaaaatgatt
    16561 atagacccta ttaagggaat gatagattag gtggtaatat gagatttcat ataatgacac
    16621 tttttccaga aatatttaat tcgtacatgg atgaaagtat aatgaagaga gcagttgaaa
    16681 aaggtataat tgaggttcat atatataata taagggattt ttctaataat aaacataaaa
    16741 aagtagatga ttatccattt ggaggaggag cggggatggt aatgactcct caacctatat
    16801 atgacacata taagcatata ataacaactc ataatataaa taacccaagt gtaatttatc
    16861 ttactccaaa aggtaaggta tacaatcaat ctatggcaaa gcagatgtct ttaaaagaag
    16921 atataatact actatgtggt cattatgaag gaatagatga gagaatcatt gatttaatag
    16981 ttactgatga aatttcaatt ggagattatg tattaactgg gggagagctc ccagcactta
    17041 taatgataga ttctatatcg agattaatac caggtgtatt aaaccaagaa gaatcatttg
    17101 aagaagaatc atttaaagac aacttattgg aatatcctca ttacactaga cctagagatt
    17161 ttgaaggatt aaaagtacca gaagtgcttt tatcagggaa tcataagaag atagatgagt
    17221 ggagaagaga agaatctata aggataacca aagaaagacg atttgattta tataaaaaat
    17281 ctaatgaaaa ataaaaatat aatgaaaaat taatatatat gtatacaata aagtacctat
    17341 aaatggaatt aaaaacataa aagtgcttgt aataactatt gaagtatagt ataatataaa
    17401 atgttgaaaa tacgggcgtt cctctgttta cactggtcgg gtagttaaga acgtctatga
    17461 tatctaggag gaagaaagat gaatgaaatg ctaagagcaa ttgagcaaga acaattaaaa
    17521 aatgaagttc ctaattttgg acctggggac acagttaaag tacacgttag aattatagaa
    17581 ggaaaaagag aaagaataca agtattcgaa ggtgtagtat taaagagaca aggtggagga
    17641 gcaagagaaa ctttcacagt tagaaaaatg tctttcaatg ttggtgtaga aagaactttc
    17701 ccagttcact ctccaaaaat agaaaaaata gaagttacta gaaaaggtaa agtaagaaga
    17761 gctaaactaa actacttaag aggtagagta ggtaaagctg ctaagataaa agaagctaga
    17821 aataaataat taaaaacttt acttataaat ggggggctga tttatcagtc ctctttctat
    17881 tttaatgaaa attacagcaa ataattatac tagaaataaa tagaaatatt tgttgaaaat
    17941 atacattatt tatctatgaa tttatagctt ttaaaatgaa aaataaaatt ggtaaatatt
    18001 gcattatatt ttgtaacaat attaaaaata agagaacagt attatgtaaa gtatgacgtt
    18061 aaaaagatga caatattata gtttgttaag atagattttt taagtggaat taggatataa
    18121 taatataata ttaataagga gtgatacatg tgtcaaatga atacgaagag tatcttatga
    18181 atgacaatct acatataaac tggtatccag gtcatatgaa aaaaactaag gagttagtaa
    18241 aaaataactt aaaattgatt gatgtagtaa ttgaactttt ggatgctaga atcccgttta
    18301 gtagtaaaaa tccagacata gacaggcttg taggagataa gccaagagtt gtcgtactta
    18361 ataagagtga tatggcagat agggataaat tgaatcaatg gattgaatac tataagaaaa
    18421 ttaatatcaa agctatacca gtagatacaa taaaaggcgt tggtataaat aagataatcg
    18481 aagaatgtaa aaatgtaact agagaaaaaa tgagttcttt aaaagacaaa gggagaaaag
    18541 aaagagctat acgaataatg atagttggag ttccaaacgt tggtaaatcg tctcttataa
    18601 acaaattaac aggtagaaaa agcactcaaa ctggagataa gccaggagta acgaaaggga
    18661 aacaatgggt tagattaaag ggaaatcttg aacttttaga tacacctgga atactttggc
    18721 ctaagtttga agaccaagaa gttgcattaa atttagcatt tagtagagct ataaaggatg
    18781 agattttaga tactgaaact ttggctttaa gacttataga gaaacttatg aaaatagaac
    18841 ctgagaagtt gaaagccaga tataagttag attgtctagg agaaactcca attgaaacta
    18901 tggatatgat tggccataaa agagggttta taacaggtaa aaaagaacta gattatacac
    18961 gcatagccac aactgtatta aatgaattta gagatggaaa aataggaaat ataacattgg
    19021 aagttccaga aaacgttaaa agatagattt taaaacaaaa tcaaaaattt aatgttaaaa
    19081 atttaaaaaa gccttttagc aaaggctttt ttattttttt gaaatataga caaatatctc
    19141 catataaaag tataaattag gttagaaaac ctttaaaaat attaatttaa gacaaatata
    19201 cctaatattt tgaaaattaa aatgagtgtg attatttaaa attttagcat attgacttgc
    19261 ttgtttcgta taatatataa taagcacaaa taaatacaat atattaaaaa tttaatttat
    19321 ttaattttat taatttaata ataagttctt attgtttaat tcaacttact tatgcaagcg
    19381 taaacaatcg agacatttta ttaatttaat aaggttaaaa agggggattt tataatgggt
    19441 aagaccaagg atgttatagt atttggattt gcgttatttg caatgttctt tggagcaggt
    19501 aacttaatat ttccacctta cttgggaata attacaggtc cagaatggtt aattgccttc
    19561 ttaggattta cgtttgctga tgctggattg gcacttctag cagtaatggc tacagctaaa
    19621 ttcgatggaa acgtagttga aatgtttaaa agatgtggta tgaagttagg aattcttata
    19681 ggttgtgcag atattttatg tataggacca ttcttagcta taccaagaac aggtgcaaca
    19741 acttatgaaa tgggtataat gcctttgttt ggaacttcaa ttccagtgtt attattctgt
    19801 atactttttt ttgcgatttc atatgtacta acaataagac cttctaaggt cgtagatata
    19861 gttggacagt ttttaactcc agctcttcta atagctttag catttataat tataaaaggt
    19921 attatatcac ctcttggaga tatagtagat aaacctatga tacctaatgt atttgcagaa
    19981 ggtataggtc aaggatatca gacaatggat gcttttgcag caatagcact tgcatcagtg
    20041 ctaatagtat ctttaaatga taaaggatat tctactatta gtgacaagtt gaaaatgatt
    20101 ggtaaggcgg gtgttcttgc ttgtggagga ttagctctag tttatggagg attatgtttc
    20161 cttggggcaa ctgtatcaac aatgtatgga acagatgcag tacaatcaca agtaatagta
    20221 aatataactg aaggattgct tggaaatgtt gggaaagcga ttttagcagt agtagtatca
    20281 ttagcatgtt taactacatc tataggtctt acatctgcca caggtcaata tttctctaga
    20341 cttacaaaag gtaaattgag ttatgaaaaa atagtattag ctgtatctgt attcagtgca
    20401 gtagtagcat cttttggtgt tggaactata ataaagatag catctcctat actaagtata
    20461 gtttatccac catcaattgt tttaataatt ttagctttct tcaatgaaaa aattaagaat
    20521 gataatgtat acaaaggagc agtatatatg tcattgtttg taagtatact aacagttata
    20581 tctagttatg gagtagctgt tccagtagta aattctttac ctcttaattc attaggattt
    20641 aactgggtgg tgccagttat aatagctgga ataattggta attttatacc atcaaagagt
    20701 caatctaata cacttggaac aaactaagtt ttgtttaatt aaaatataat caattgtaaa
    20761 taaatgagtt aactaaaagt aaaaggagtt atttgtacaa ataactcctt ttatttttag
    20821 attctatatt taattatttg tatttaatat ggaaaaagta taagaaaata tcaaaaaaat
    20881 atatggttta ttttttaaca ataatagaga ttaaaaaaga attttagagt aattttataa
    20941 atttaagtat acatattaaa tgatttttac aaaaatataa tataaataaa attgtgacaa
    21001 taataaaata ataaaacaaa atttaagaca tatgattata taaatgtatt aaataaatga
    21061 gtaaattgtt ttcattgaga gatatattaa gaatttttag ttaattatga catataagta
    21121 tgtaaacgtg aatactagca actgcaaagt ttaagtaagt tggaagttag agagtaattg
    21181 ttatgaagaa aaataagttg ataaatcata ataaggaatt ttcagaaaaa atggttttaa
    21241 gagtaaaaaa caagaggcaa atctacgcaa gtagaataaa aattgaataa agttaactgt
    21301 caatttagca aaataaatac aaaatactac aagaattaac gtaaataggt gttatgataa
    21361 aaggaaaacg attttttaag aatcataatt ttgaaaatta aaaaaattaa aaatgctatt
    21421 gactgctttt ttttcagatt atataataaa cacaaaatat ttaaaattta aattgaatta
    21481 aaaagattat atgaatgtaa aaaaggagag tgatatatac agtatataaa gcaatacaac
    21541 ttaataataa atcgaataat ctaaaaagtc ttaatatttt aattattcgg aatagttaat
    21601 tttatcaaga aaaattagag aaaaaacaaa aaaccaacta tgtttaaagt atacaggttg
    21661 attttgttta attaagaaag ttgtattaaa tattgtgaag attttataaa ttatgaaaca
    21721 taattgacaa atttaagtca aaaatgtata attaaataaa atctcgtcaa aaggttttca
    21781 tttaattaag agattggact tattttttag taaaaggtag taaaattcaa atgggggtgc
    21841 tttaaatggg tgagaaacaa atcaatttta aagatgtaat tgtaattgga tttgcactat
    21901 ttgcaatgtt ttttggtgca gggaacttaa tcttccctcc atatctagga gttttatctg
    21961 gaagtagttg gctagtagct ttcataggat tcctttttgc agatggtggt ttggcattat
    22021 tagcagttat agcagcaact aagttcaatg gagacacatc gaagatgttc tcaagggcag
    22081 gcaaaggatt aagtattgca ttaggatgtg caatggtaat ctgtataggg ccacttttag
    22141 caatacctag aacagcagca acaacttatg aaatgggtat attacctaca ataggttctg
    22201 gaataagccc agtaatattc tctatagtat tctttgctct agtattggtt ttaacaataa
    22261 gaccatcaaa agttgtagat atagttgggt caatattaac tccagcttta cttatagctt
    22321 tagcagtatt aatagttaaa ggtatcgtat ctccattagg agaaataaga gacagttctt
    22381 taatacaaaa tgtatttgca gaaggtataa ctcaaggtta tcaaacaatg gatgcattgg
    22441 cagctagtgt atttgcatca attataatca tgtcagtaat agctaaaggt tatacaggtg
    22501 agaaagaaaa gatgaaagcc acaataagtg caggtgtaat tgcagtaata ggaatggcat
    22561 tagtttatgg tggattatgt tatcttggag caactgtgtc tcaacaatat ggacaagatg
    22621 ttcaacaaac agctttaata gttgcaataa cagcagcttt acttggaact acaggtaaaa
    22681 ttttattggc tattatagtt gcattagcat gtttaacaac agctataggt ctttcttcag
    22741 cagctggtca atatttctca acacttacag atggaaaatt aaagtatgag catatagtta
    22801 tagtagtttg tgtatttagt gcaatcatat caaactttgg agtaagtaca ataatacaat
    22861 tctcttctcc tatactaagt atggtatatc cagcaactat aactctagtt atactagcat
    22921 tatttagtaa taaaattaaa aatgacaacg tgttcaaatg tgctgcatac atggcattat
    22981 tagtaagtgt attaacagtt gcaacaagtt ttggtgtaaa aattcctcta gttaatagct
    23041 taccatttgc ttcattagga tttaactgga tagttccagt tgtaatagca ggaataatag
    23101 gaaactttat tccatctaaa agcagtaaaa ctgcataata ataaaaacta attgataatt
    23161 atggaattgc ctttaaatta tataggcaat tcctttttat atttaaaaga attattaaat
    23221 tattgtagat aaaagaacat tattaatcct gtttgataaa tttaaaaatt tatttttgaa
    23281 gtagtatgat
//
LOCUS       DAEHWO010000059        23234 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEHWO010000059 DAEHWO010000000
VERSION     DAEHWO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23234
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.059"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(180..548)
                     /locus_tag="KNP54_002735"
     CDS             complement(180..548)
                     /locus_tag="KNP54_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0893608.1"
                     /translation="MKKIPKSELLVMNFIWDKDIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLGC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(1076..1498)
                     /locus_tag="KNP54_002736"
     CDS             complement(1076..1498)
                     /locus_tag="KNP54_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBF0893609.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            1976..4879
                     /locus_tag="KNP54_002737"
     CDS             1976..4879
                     /locus_tag="KNP54_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893610.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEEDEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKISDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDESLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            4912..5358
                     /locus_tag="KNP54_002738"
     CDS             4912..5358
                     /locus_tag="KNP54_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0893611.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGDMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            5481..5783
                     /locus_tag="KNP54_002739"
     CDS             5481..5783
                     /locus_tag="KNP54_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0893612.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            5964..7370
                     /locus_tag="KNP54_002740"
     CDS             5964..7370
                     /locus_tag="KNP54_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBF0893613.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPVITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            7714..8772
                     /locus_tag="KNP54_002741"
     CDS             7714..8772
                     /locus_tag="KNP54_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBF0893614.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVNIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMEKGDIIFKPMISDKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            8871..9557
                     /gene="araD"
                     /locus_tag="KNP54_002742"
     CDS             8871..9557
                     /gene="araD"
                     /locus_tag="KNP54_002742"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBF0893615.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            9575..10222
                     /locus_tag="KNP54_002743"
     CDS             9575..10222
                     /locus_tag="KNP54_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBF0893616.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(10395..11762)
                     /locus_tag="KNP54_002744"
     CDS             complement(10395..11762)
                     /locus_tag="KNP54_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBF0893617.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(11952..12040)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12468..14588
                     /locus_tag="KNP54_002745"
     CDS             12468..14588
                     /locus_tag="KNP54_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBF0893618.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRLFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            14692..15945
                     /locus_tag="KNP54_002746"
     CDS             14692..15945
                     /locus_tag="KNP54_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBF0893619.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVIAMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(16099..17160)
                     /gene="ytvI"
                     /locus_tag="KNP54_002747"
     CDS             complement(16099..17160)
                     /gene="ytvI"
                     /locus_tag="KNP54_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBF0893620.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            17434..18174
                     /locus_tag="KNP54_002748"
     CDS             17434..18174
                     /locus_tag="KNP54_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBF0893621.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            18186..19964
                     /locus_tag="KNP54_002749"
     CDS             18186..19964
                     /locus_tag="KNP54_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0893622.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            20131..21048
                     /gene="pfkB"
                     /locus_tag="KNP54_002750"
     CDS             20131..21048
                     /gene="pfkB"
                     /locus_tag="KNP54_002750"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBF0893623.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     IFKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            21085..23004
                     /locus_tag="KNP54_002751"
     CDS             21085..23004
                     /locus_tag="KNP54_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0893624.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         9251 a         2511 c         3933 g         7539 t
ORIGIN      
        1 tttaaattta ttttagatat aaacatcatt ctgactacta ttaaaagaca tataaaataa
       61 ttaaacttaa aagtatattt gcttatcttt ttagtaaata aaatgaaaaa aagaattagt
      121 ggacttatgt aaatattaaa tttaataact tctataaata attccataaa atacgtctcc
      181 tattttcttt tttttagcca ttgttcaagt tcttttatgt catcatctga tatttcattt
      241 ccacaaccta atgatgatat aaagctatga atagaatttt tatgtataag ctctaaaaaa
      301 tcctttgttt caaattttag atattcctca tgtttaactt taatagtgta taaagtattt
      361 ctaccatctt tttcaaattc taaaaaacct ttatcactta atctagaaag tactttacca
      421 gtagtacctt ttgtccatcc atgagaaatt tccatataat tagctacttc tctggctggt
      481 attttatcta tgtctttatc ccatatgaaa ttcataacta acaactcgga ttttggtatt
      541 tttttcaata taatcactca cctttaactt gattatatta gacaaatgtc taatagtcaa
      601 tataatatat catcatgtat aaataatctt tatattattt tatgcttgag aactaagtag
      661 tatagattta tagataaaaa agatattgag agttttatgg aagaggggaa tatattttct
      721 attagagata agaatatgac atatattttt tattgatttt tacaaaaata ctatatagtg
      781 aataaattaa tatcttttct aaattagaag aggagaatct tattagataa agattatcct
      841 ctttattgaa agtttaaggg atattagaga ttattaattt ttctctcttt ttttaactaa
      901 aagcaataat acataaaatt attattgcta atgatactct taatgtggta tatagtcata
      961 gtgtcacatg tttatcaata gttttttcat taattattgt aacgaatagt aggactcata
     1021 aaatacttag aaatatgttt ttagatagat tttaaatata taatctaact tatatctata
     1081 aattaacact attattctcc aattccattt ctagtttttt tataaattta ttaaattctt
     1141 ctggttgcct ttttccaaac aatactctta caagagctga attgattttt ccaaatatat
     1201 tcctcttgct ctcactttca ataaaaataa gttttgtatt ttctaagtca atatgtacta
     1261 attcatatct agtaatagta ctttctcttt tattgcttgt ttttatctca tatactctat
     1321 ttttttcgaa attagttatt tcaaccttaa atcttttatt atttttttgc tgtacaaatg
     1381 ttcctactgc ttttttctca ttaaaattag gaaaatttag tcttgcagat tttgtaaata
     1441 tattaaatat gtcttttgca gaatatttta ataaaacttc agttttaaat gtattcatat
     1501 cgttttccct tctgtatata aatttaatat ttataagtta atttttaagt taaaatagta
     1561 taatatgcca tattaaatca tgttaaaact atttatatag ctaaaatctt acctatataa
     1621 gtatgtatac tatcatataa aaataaaatc ttaaaataga aagggttaaa aacacagttt
     1681 attataattt ttattgttga gtagatacgt actattatat atgattgagc aagtttttca
     1741 atcataaatt tataaagtat tttgcattaa aatttaaaca aagaattaaa ttatttaaga
     1801 ttatgaataa ctaatacatt tagtaaatta ctaaatatac aaaatgtaaa tacttatcaa
     1861 aatgtataaa tacttatgac atctagttac ttacagggtt taagtagaaa aaaatatcaa
     1921 agtaagtatg gcatgatagt tgcttatata tttatcaaga aaggagttat taagcatgga
     1981 gttgagagat aaacttgtaa acatcataaa tacagaaaat aaaaaagatc cattaacaga
     2041 tgttcaaata gcaaagtttt taagtacaac tagagagaac ataactaatt tgagaaaaga
     2101 acttaatata agtaattcaa ggcaaagaag atatccttat ttaaaatcag caatttcggc
     2161 aatattacaa aagaataaga atatttctat atcagaaatt acaagggaat tgatgacaga
     2221 aggctttaat atatcgagaa gagttgtgga ggaactttta cctaaagaaa gtttagaaat
     2281 ggatgtagta gaggaagatg aagaagaatc gaatgaccca tttgaaactc tgataggtaa
     2341 taaagggagt cttagaaatg ctgtagagca ggctaaatct gctatattgt atccaccaaa
     2401 agggttacca acgttgatta ttggggaaag tggagttggt aagagtttat tttctagaca
     2461 tatgtatgag tttgcaaagc aaaaaaagat agtaaaagag agctccaatt ttgttgtatt
     2521 taactgtgct gattatagtg acaatccaca attattatta tctttgttat ttggatataa
     2581 aaaaggtgca tttacaggtg ctgaatatga tacaccaggt cttgtagaag aagctgatga
     2641 aggagtttta tttttggatg aaatacatag attgcctcca aaaggtcaag aaatactatt
     2701 ttctatctta gataggggaa agtttaggag attaggtgaa actaatgctg aaagaaaagt
     2761 aagtattatg ttgattgggg caactactga aaatgtagag actaatttat tattaacatt
     2821 cagaagaagg ataccaatgc taataacttt gccaccatta catgatagat tactaaaaga
     2881 gaaaatagac cttatataca atatctttca acaagagtgt aatagaataa atgcaaaaat
     2941 atttgtagat aaaaatgtga ttgaaatact tgcactaaaa aagtttagtg gaaatatagg
     3001 acaattacaa aatatgattc aggttctttg tgcaagagct tttatgaagt ttataaattc
     3061 caaagatgaa gatagtgaat ctatagtagt agtagatata aatgaagttt taaagcttaa
     3121 agattcgttt aaagatgctg cctttcaaga gattgaatat acagagataa gaaaatattt
     3181 gaaaaatgct atatttatac catttaattt agaagaatca tcagtaaaag gaagtctttt
     3241 aagtgatgaa tatatattac cagaggacat atacaaaaca attgaaaaga aatattatga
     3301 cctaaaatcc ctagacattg aagatataga tatagagaat attttatgga cttttatttt
     3361 aaatagattt gctgacttaa agtttaatct tgatagtaat gaagaaattt tttcaatgag
     3421 tgatttaaat agttttgtaa gtgatagttt agttaaactg gtaaaagaac ttatgaatga
     3481 tatagttgaa aaaaatatga atttagaagt aaataaaaat atgttcaaat atctagcaat
     3541 acacttagaa gaagctataa aaagaattaa gctaaatcaa aagataataa atgtaaattt
     3601 agaaaaaata aagattgact tttcaaaaga atatgaaatt agtaaaagtt ttgcaataaa
     3661 aattgaggaa tcaattggta ttaagatttc agatgatgaa attggattta taacgctcta
     3721 cataaagtct gctctaaaaa atgaagtgaa aaaagataaa gtagggttaa taataatttc
     3781 tcatggacgt atagctacag agactgtaaa tgtagttaaa gaacttttag gtgtaaagtt
     3841 tcctgtggct atagatatgc ctttagatga aaaaccaata aatatataca ataaggcagt
     3901 agaattgtca aaaataatag accaagggaa aggcatattg tttttggtgg atattggttc
     3961 acttacaaac ataggtcaaa tagtaaataa gagaaccaat ataagtacta aaactattga
     4021 tagagtagac ctcctaatgg cactagaagc aactagaaaa gtttctatgg gagaggaaga
     4081 acttgatgaa atattttttt ctttgctaaa agataggatg ggatataact atgaattaga
     4141 aaaacacata gataaatcaa atgcaattat aacattatgt cttactggag aaggaactgc
     4201 taagtatata agtaaaacgt tggaagaaaa gtatgataac actaaatgtt atcaaatgag
     4261 tgcattggat gaaagtttat tttgtaaaat tgaaaatcta aaagagacaa acaatatatt
     4321 agctattgtt gggacaataa accctaagat accaggtata aattttatac cctataataa
     4381 agaacttttc aaaaatttgg atatctatct atcaaaatca aaacaacaag atgacagacc
     4441 aattaaatcg tatgaaagaa tgcttgatga ggatttagtg atttttgaac cagatatata
     4501 ttttaaaaag gatttattag aatatgtatg ttcaattctt ataaataaag aatatgtaga
     4561 aaaagattac ttagattctg ttttacatag agaagaaatg cttccaacat attctaaagg
     4621 agctataggt gtgcctcatg gagattcttc tactgtaaat agtacaaggt ttgtttttgt
     4681 taaactaaag aatcctattg attggggtgt aggtaatgta aatttcatat ttatgccagt
     4741 ttttcaggct aatgataaag agattgttaa aaatgttctt gagatactaa aagatgcaga
     4801 atttatgaac aatgccaata agtgttttga taaagatgct tttagaagga ttatatttga
     4861 taaatttaaa catctgtagc catagcaaaa aaattgagag gagttagagt aatgaatgta
     4921 gatttaatat cattgggttt agaatctaat gattatgaaa gtgttattga agaattagga
     4981 agtataatgt gtaaaaaaga atatgtaaaa gaaacataca taaatgctgt cttggaaaga
     5041 gaaaggacat taccaacagg tctagatatt ggagacatgt gtgttgctat tccacataca
     5101 gattcaaagc atgtaaatga gtctaatgta gctgtaggga tattgaaaaa tcctgtaaag
     5161 tttaattcaa tgatagaccc aaaagataga cttgatgtag aacttgtatt tttattagca
     5221 gtaaagaacc cagactcaca agtaaaactg ttaaaagatt taatgtcagt ttttcaaaat
     5281 ataaagttat taaaaaatat aaaaaacgca tcaacaaaag aagaagtagc taaattattg
     5341 gattttatag aaatttaatg taggagaatt ttataaataa aaaattaaaa tttaaacaat
     5401 caaagtaagt attatttttt taataggttt aatcttatat aaaataaaaa tttagagtga
     5461 aaaattagga ggaaattatt atgaaacaat ttaatgtatt atcagtttgt ggttcaggga
     5521 cagttacatc atctatggta gcaggtaaat taaaagaagt actaggtaat aaggggattt
     5581 ctattactac aacagaagct agaccaacag aagcactaaa tttagcacaa tcaggaagat
     5641 ttgactttat aacatttacg agtccacttc aaacaggcga ttatggaata ccaactataa
     5701 atgcatttgc ttgcctaact ggtatagggg aagaggcatt ctttgaagaa gttttgactg
     5761 ttattgaagg gatagataag taagttttgg agacgtgaat ttatagtatt taaatcaatg
     5821 atttagatac tataataagc taatattaac taaatatttg tggaaaaaac attttatatg
     5881 ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt attaaattaa gcttataaat
     5941 atttataagt aggagggaaa aagatgttag aatttatgaa atctataatc gatacatttg
     6001 gttctgcaat tatagttcca attataatat tcataatcgc aaagatattt aaagtaacta
     6061 ctaagaaatc gtttctttct gctgtgtatg caggagttgc tttacaaggt tttacactga
     6121 ttttaaattc atttacacca gtaataacac cagttatcaa taggatggtt gagagtacag
     6181 gagtaaacct accagttttt gatgttggtt ggcaagcaac atcattggtt gcattttcaa
     6241 caagtgcagg tatgatatat ttaggtcttg gtatattatt acaaacaatt ttatttttga
     6301 taaaatggac agatgtgttt caaccatcag atttatggaa taactattct tatatggtat
     6361 ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca tgtatggttt
     6421 tattaaacct atatagttta ttaatatcag agttagttgc aaagagatgg tctagttact
     6481 atagatatcc taattgtaca ataatagcta tgcataatgt tgaggcttct gtgtttgcag
     6541 tatttgcaga ccctatatac aataaattgg gattaaataa aataaaatta aatccaaaag
     6601 aattagagaa gaaattaggg tttttaggtg aaccaattac tttaggtctt tttttaggta
     6661 tgtttatagg tatattaggt aatatgacga gaataaatac tatggaagct tggggagaaa
     6721 taatgaaagt aggtatatct acaagtgcag tgatggcaat tttccctaaa gtagcaagta
     6781 tgtttgctca agcatttgca cctataacag aagcagctag aaagattatg caaaaagctg
     6841 gaaaccgtga gtggtacata gcagtaaatg atgctgttgg atatggtgaa cctgcaactt
     6901 taatatcagg tcttatatta attccaataa tgcttgtaat agctatggta cttcctggta
     6961 ataaggtatt accagttgtg gatttattgg caattccata tatggttcaa ggtttagttg
     7021 ccatacataa tggtaatata ccaaaagtat tagtttcagg tataatttgg tttggattag
     7081 gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca aatataggtg
     7141 tagctatacc tgcaggagca atgttaataa caagttttaa tatactagga aaacctttga
     7201 tgggattagt tttctttgca tttctaagtg caaatccaat ttatataggt ctttcagttg
     7261 taatttactt tgttctatgg gcattgttta gaaagaacaa aacaagtatt cttgattatt
     7321 tagaaaaaca agcacttaaa aatgtagaag aagagcctgt agcagtttaa gtttataaaa
     7381 atgaaataaa aataattaaa ggagtttata attgatttta tataagtatc agataatacc
     7441 tgagaaatat ttaaatgaaa tatagacttc tttttatttg ataatatttg taattataat
     7501 gcattgtatt tttatagttg agttttctgt ataacctgct atttaaaaca tactctttta
     7561 tatttataca gtaatgtggt ttaattttat aaaatgtaat ctctactggt aaaagacttt
     7621 gtatataagg catttgcctg aataaaccat ttatcttttg tatggcatag atattgctat
     7681 atagaagtat atagcatgaa aggagatatt tatatgggaa ataaaatgag agcatcagta
     7741 ttgtataatg taggtgatgt cagatatgaa atggtaaata taccagaaat aacagatacg
     7801 caagtgcttg taaatgtaaa atatgttggg atatgtggtt cagatttacc taggtctatg
     7861 gtaagtggtt tgagtggaaa tacaaaatat ccattgattt tagggcatga attttctggt
     7921 gaagttgtta aaattggaga aaaagtaaag catattaatg taggagatag agtagctgtt
     7981 gcaccattag taccttgtgg aaaatgtgat tattgtaatg aaggtaattt tggcttgtgt
     8041 gatgattaca atataattgg aacaagagta aatggagcgt ttgcagaata tgtaagagtt
     8101 ccagaagaac atattttaaa actaccagat acattggatt atgaaactgc tgccggaatt
     8161 gaaccagcaa ctatagctta tcatgggatt tcaaagtcta atattagagt aggagatagt
     8221 gtagttgtgt taggatgtgg tccaataggt cagtttgtta tacaatgggc aaaggtgttt
     8281 ggtgcatcta agattatagc agttgatatt tttgatgaaa aattagaact ttctaaactt
     8341 ctaggagcaa actatatact taactcaaaa gaagtaaatg taatcaaaga aataaaaaaa
     8401 ataacaaatg gtggtgctga tgttgtaata gaaactgctg gtagccgatt tacacaagaa
     8461 caatctctat ttgtagcaaa aaagagagga aatatagtgt ttgtaggtat atcacacaca
     8521 gaattaccac ttagtgcaga cgctactgag tgtatattac gtggagaact taccttgaaa
     8581 ggttcttgga attcatatac aagcccttat cctggaagag catggactgc aacattggat
     8641 tttatggaaa aaggtgacat tatttttaaa cccatgattt cagataaaat aggtcttaat
     8701 gaagtgggtg actttttaag taaaatgagc aagagagaaa ttaatttcaa taaaatccta
     8761 gtagaaatat aaaaatttaa taaaaaattc taaaagcaat taaattttat aactatgaca
     8821 ttaaataaaa taaaaataat tttcttaaat aaaatatagg aggaagaaaa gtgttagaaa
     8881 atttaaaaga agaagtatta aaagcaaact tagaattacc taagaaaaag ctaattactt
     8941 atacttgggg aaatgtaagt gggatagata gagaaaaagg attagtggtg ataaagccaa
     9001 gtggtgtaga gtatagtaat atgactgtag aagatatggt tgtagttgat ttagagggaa
     9061 atatagttga tggcaaatta agaccttctt cagatacccc gactcatcta gttttatata
     9121 aagagtttga agaattgggg ggaatagtac atacacattc aagttgggca acaatttggg
     9181 ctcaaatagg aaaatctata ccatcttgtg gtactactca tgcagattat ttttatggaa
     9241 gtataccatg taccagaaaa atgactagag aagaaatttg caatgaatac gaaaaggaaa
     9301 ctggaaatgt aatcattgaa gaatttatgg gaagaaatcc aattcattgt ccaggaataa
     9361 ttgtaaatga ccacggacct tttacatggg gaaaagatgc aaatgaggct gtacacaatg
     9421 cagtagtttt agaagaagtc gcaaagatgg cttattatac agagttaatg agtcctgata
     9481 atattatgga taaggttctt atgaataagc atttttcaag aaaacatgga aaaaatgcat
     9541 actatggtca aaaatgatta tctggaggtg aattatgcta gactctttaa aaggtaaagt
     9601 tgtggaaata gcaattaaag cagagcatta tggtttatgt aaagaaaaga ctggtaattt
     9661 tagtattaga gataaggata ctggatatat acttataacc ccatcaggtg taggaagaga
     9721 agaattaaaa gttgaacata tttgtgtatt ggatttggat ggaaatgtaa tagaagttga
     9781 gaaaggtatt aagccaagta gtgaggtatt gatgcatatt gaaatataca aaacaagaga
     9841 aaatataaat gccatatcac atactcattc tttatatgca acagcatttt cagtagcaaa
     9901 gaaaccaatt ataccaattg tatatgaatc agttaattat ggcggttatg tagatattgc
     9961 ttcatacgaa agaccaggaa ctttaaaatt agctaagagt gtttcaaaat tactgataga
    10021 tacagatgca tgcttattag aaagacatgg gttgacaact gtaggtaatg atttagacga
    10081 agcattatta aaatcaagat atgtggaaga ggtagcagaa atatactata ggtctttagt
    10141 attaaatcaa tttaaagaac ttgaagtagt agatgttgat gagtttaaat cttggaaata
    10201 cccagaagaa ataaagtttt aatctaaata attttcattg aagtggttaa ttaaaatata
    10261 tgtattattt atatcaatta ctatgtttta ttatgttaat taccgtattt tgcaaatata
    10321 tttattacat tttttcaaaa aaatatagaa tccgaaagcc atataaaatt gacttgggat
    10381 tctatacttt ttatttatgc atttttcttt atctgatttt ctggagaatt tatatgttca
    10441 aaatattttt tagtttcaga tactattata ggtgataatg caagtaaagc tataaggtta
    10501 ggtattgcca taagcccatt tacaatatca gcaattatcc aaacaacttc taactttaag
    10561 aaagcaccta ataacaccat agccacaaat acagttctat acccattcat gccttttaca
    10621 ccaaacagaa attcaaaaca tctttctcca taataactcc atcccaaaat tgtagtaaat
    10681 gcaaataatg ttaaactaac tgtaagtaat attggtccaa atgtaggaat tgctccgtta
    10741 aaagctgctt gtgtcataac agctccattt aggtctgaac accacactcc tgaaataaca
    10801 agagagaatc cagtaagagt acagattata atagtatcta taaaagtacc tgtcatagat
    10861 ataagacctt gttccgctgg ccattcagtt ttagcagcag ctgcagctat tggagcacta
    10921 cctagaccag actcatttga aaatacacca cgagcgatac catttctaat tgccagtgac
    10981 atagttgctc ctaaaaaacc accagtagca gcagtaggtg taaatgcact tttaattatt
    11041 aacataaaag tttcagggat tttattccaa aaagatatta aaatgattcc acagattaca
    11101 acatatataa ctgccataaa aggtactatt ttagtagcta cattagatat acttttaagt
    11161 cctccaaata caactaaagc tacaaatact gctaatacaa cccctgtaat tctagggtct
    11221 atcccgaaac tattatttat tgcatctgtt attgaattta cttgagtaaa agtaccgatt
    11281 cctaaaagtg caactagtat accacttata gcgaaaaata ttgcaagagg tctccatttt
    11341 tctcccatac catttactat gtaatacatt ggcccaccag acacttgacc atttttatct
    11401 ttagttctgt attttattgc aagaacacct tctgaatact tagtagccat tccaaagaat
    11461 gctgctatcc acatccaaaa aagtgcacca ggtccaccag ctttgatagc tgtagcaaca
    11521 ccaacaatat taccagtacc aactgtagca gctagagcag tacataaggc tgcaaaactt
    11581 gaaacatcac cactaccttt gttttcagca gagaatatta acttaagagc tcttggcagt
    11641 ttagttattt gaacaactcc aagcttaaca gtaagtagta taccagtacc aactaatagt
    11701 accagtaggg gtggtcccca aataaaagca tcaactttgt ttaaaatatc aattagattc
    11761 ataaaaacac tccctcattt tttttgcttt acataatcaa tagaattttt aatgaagtaa
    11821 ttgacaggaa ataagtataa tttattaata atttctagtg taataaaaaa agctaaatct
    11881 aaaaaagatt cagctctgga tgtacactaa ttagcaacca aaataaaagt attagtaaat
    11941 actgtttttg gtagataatc cctgtccttt tgcctgagag attgagcata aaagccttgc
    12001 cccttcggcg cccataatgg gtctctccag agttccgtaa attttacagt cctactttta
    12061 aaagtacctg agagtgttac tccttcggtg tgctatatag caactcttct ataaaatctt
    12121 aaccggatat tgatttgtca tagcttattg tattaataat attaatataa gtttttatgt
    12181 tttgtcaact aaaaaattaa aaaacaaaga aaaaatataa aaatgtaagc ctatttacga
    12241 attataaact tagaaagatg agtaatatac gtgaaaatga attttgtaat acacatacaa
    12301 atgaagtgta aaataagttt taaataaaaa aataataaaa tcttaaataa ttaattagat
    12361 atgattaaat tatggtaata ttatagttac gatattaaga aaagttctat ttagttagat
    12421 tttaagcgta atatgagatt atgtatagag aaaggatgta tttttagatg ggaaaaatat
    12481 tagtgctagc agaaaaacct tctgttggaa gagatatagc aaaagtttta gggtcaaaaa
    12541 atgaaaaaaa tggttatata gaggggccaa agtatgtgat aacttgggca ctaggtcatt
    12601 tggttacact tgctgacccc gaaagttatg gagaaagata taaatcatgg agcttagaag
    12661 acctgccaat acttcccaag caccttaaga ctgttgtaat aaaaaagagt ggaaagcagt
    12721 ttaatacagt taaatcgcaa atgaatagaa atgatataga tgaaatagtt atagcaacag
    12781 atgcaggtcg tgaaggagaa cttgtagcaa ggtggataat agaaaaatca caggtaaaaa
    12841 aacctataaa acgtctttgg atttcttcaa gtacagacaa agcaataaaa gacggatttg
    12901 caaaattaag aagtggaaaa gaatatgaaa atttgtatta ctcagcaata gcacgagcag
    12961 aagctgattg gattattgga ataaatgcaa ccagagcttt gacaacaaag tacaatgcac
    13021 agctttcttg tggaagagta caaactccta ctcttgcaat gttgcttaaa agagaagaag
    13081 aaataagaaa tttcaaacct aaagagtatt atggattaga attaattgct acaaagggaa
    13141 attcagatat aaaatttatt tggaatgata aaaacaataa ttcttcaact tttagtaaag
    13201 aaaagataga atccacatta aaaaaagtaa aaggtgtaga cataaaaata tctgaagtaa
    13261 acaagtcata taagaaaaaa tattcacctg cactctatga tttaacagaa ttacaaagag
    13321 atgcaaataa aatgtttgga ttttcagcaa aagaaacttt atctataatg caaaaactgt
    13381 atgaacatca taaagtactt acttatccta gaactgattc tagatattta acatcagata
    13441 ttgttggaac attaaaagat agaataaaag ctgtaaatat tagtgattat tcaaagattt
    13501 gtaatagatt attaaaaagc aatattatag ctaataaatc gtttgttgac aattcaaagg
    13561 taacagacca ccatgcaata ataccaacag aacagaaggt attcatgagt gattttagtg
    13621 ataaagagcg aaaaatatat aatcttgtag taaaaagatt tttagcagta ctatctcctc
    13681 cttttgaata tgagcagaca actataagtg caactgtaga aggagaaata tttaaggcta
    13741 agggaaacaa agtaataaat ttaggttgga aagaaagtta taaagatatt gaagatgaag
    13801 atgagtatga aagtatacca aatgttttag aaaaagatgt acttaaggtc aagggattaa
    13861 agataacttc aggaaaaaca aatccaccac catacttaaa tgagggaaca ttattgactg
    13921 ctatggaaaa gaatggtcta gggacagttg ctacaagagc agatataata gaaaaattat
    13981 tcaattcatt tttaatggaa aagaaaaata aagatatata tataacatca aaaggaagac
    14041 aattattaga tttagttcca gtagacttaa agacaccaga acttacagct tcatgggaaa
    14101 agaaattatt ggatatttca aagggaaaac ttagtaaaaa tacattcata aatgacatga
    14161 aagattattc aaaagatatt gtactagaag taaaaaatag tgataataaa tttaaacatg
    14221 ataacttaac taaaaataga tgtccagaat gtggtaaatt tatgttagag gtaaatggta
    14281 aaaaaggtaa gatgttgatt tgtgaagata gagagtgtaa tactagaaaa actatatcac
    14341 aagtaaccaa ttcaagatgt cctaactgcc ataaaaaatt agaacttcgt ggagaaggtg
    14401 aggggagact cttcacttgt agttgcggat acagagaaaa gttgtcttct ttcaacaaga
    14461 gaaagcaaga agaaaaacag aaggcatcaa aaaaagatgt taatcaatat ttaaaaaatc
    14521 aaaataaaaa tcaagagaca tttaataatc catttgcaga agcattagct aagctaaaaa
    14581 acaaataatt ttaaagttat tattatacac aattataact ttaactgtat attagttata
    14641 tgtactgata taatatagtg tatagtttag gcatgaaagt agggctgtta aatggattta
    14701 agtggcatat ttaaatacta ttgtaaagag tgtgaaaata catggaataa ttcgagtgtt
    14761 gaattatttg agaatataga aacgtatagt aaagattcac aaaaaaagag ggaaaaagaa
    14821 ttagataaat tgctaaatac aatatcagtt catttagaga ggtatccaag tgatgctgta
    14881 ttgagaaaaa tgtgggtaaa aaagggcgag gttttcttac aaaagacatt ggaaaaagaa
    14941 aatattttta agttagaaaa aatggatgta gaggatagaa aaaaattttt agatataaca
    15001 aaacagttta ttagagatgc tagaaaattt gatgatgatt tacctatagg tgatattatg
    15061 caagctatga ggaatgtatg gatttcaaat gcattacaat tattatttgg taaagaagta
    15121 tattattcaa aagctaactt tgcatatagt atgttatatc catatactga taattattta
    15181 gacaatacaa atatagataa aaatgataag attttattta ataactggtt agaaaaaagg
    15241 ctcctgggag aacacattaa atctaaggat tatcatgaaa gtaaagtatc tcaaatgata
    15301 gattatattg aaagtgtata ccctagagaa aagtttacag aagtttatga atcgttatta
    15361 ttaatattta aaagtcaagt aaatagttta aaacaacatg gtaaggaaaa tcatttgtgt
    15421 aaagaagatt tattatccat ttctattgaa aaaggaggtt catccgtttt agtagatgga
    15481 tatttaataa gtggattgat gacaaaggaa gaaatagagt tttgtatagg atatggattt
    15541 ttattacaaa tatctgatga tttacaagat ataaaagaag atttaaaata caaccataaa
    15601 actattatta cagagatgtc aaaagagggt actttagata aagttgtaaa taaactaata
    15661 aattttacta ttgagttaat agatagtttt aaaattaata ataaaaataa atctgtaata
    15721 gctatgataa agaatgattg cttaatgtta attttatttt ctgtagttta taatgctgaa
    15781 tttttttctg taggatatat aaaagaagta gagaaattta ttccatatac aatagattat
    15841 tcattagaga ttgaagaaaa aataaaagaa aaatttaaaa atatagatgt tttaaataat
    15901 gaaaatgaat ataaagaaat gattgatatt atttgtgcag agtagaaaaa aagggagtgt
    15961 cttagaatag actttttagt ttatgaggca ctctttttgt ataaaatcaa atgtattttc
    16021 atcattttaa caattaaaaa gagcttatcc ctatttgaga aagccctttt taatttaaat
    16081 aaaaatgtca aggttaaact atttaaatgc agtaataatc ccattatcat gtaagttttt
    16141 tatgattgta gctgcgatag ggaatccaaa taatccagct attccaaata gttgagctcc
    16201 aacaaacata cacattaatg ttattaaagg atataggcca atttggtgtc ctactacctt
    16261 tggttctaat atttgtctaa caacggttat aattatgtat agtattaaaa gtcctattgc
    16321 taaattaata tttccattaa tgagtgagat aatcatccaa ggtgtcaaaa tacttcctgt
    16381 acccaagact ggcaaaatat caacaagtgc tatgatgaca gatatagtaa atgcattttc
    16441 aacctttagg atagtaagtc caataagtag ttctatgaat gtcactgata gtagtattgc
    16501 ataggctttt agtagtttta aaagagcatt aatactgcta ttttttatat ttattatcat
    16561 aaattgactt ttttctggaa attgttttaa gataaagttt actatttttt gatagtcaaa
    16621 agtaaagaaa aaagaagcaa ttaaagtaat aataagtttt aacataaatg caggtgtttt
    16681 acttgcaata ctagcaatag cattgagtgc atttgttgaa atagaagcta ctaaagacat
    16741 catagattga cttatattat cccaaccaag tattaatgct aggttaacat taggtgtact
    16801 agcatctatc tttgaaaata aagtatttag cgttggttgt atacttgatt tatatatttc
    16861 aggaagtcta aaaaatacat cacttacact tgcaaatatc ttcacaccaa agctaactaa
    16921 taaaaatata cacaacccat aaaaaattaa aagtattact atagaaataa gtgtacgatt
    16981 taaatttgta ttatttgtaa taagtcttat aataggtctt aagatggatg caatgataaa
    17041 actgattaca aaaggcatta ataatggcaa taagaatttt aatacaatat atacaatact
    17101 tgttattaaa actacatatg taaatttaat tataaaattc ttttgctttt gaatatccat
    17161 aatataaaac ctccaatgta tttgatatta ttctaaatat ggtctttttt acagaaaata
    17221 tactactgta tattgattat aaactataaa gcttatgtaa agtaaataaa ttatgtaaaa
    17281 tttaggttaa ttttgtataa agagatactt ttatatttta caattaataa ccaaatacta
    17341 aaaaatattt taaataaaga acttaaaatt gtgataaaat taatttatag atattaaaaa
    17401 aagtataata tatggttttt aagaggtgct aagatgaaaa attttagaga tttaggtggg
    17461 aacaaaactg aggatggcag aactgtaaag aagggattat tttataggtc tgcaaaatta
    17521 tcaaatctaa gtgaaaatga tataaagatt ttaaaagagt taaatattaa atatatattt
    17581 gattatagaa gtgatgaaga agctcgtaaa catccatcaa caataatatc aaatataaaa
    17641 aatataagaa taccagcaat gagagagcta gaagaatcag gaggaagttt tggttctatt
    17701 gaagatatga ttgatggatt gtttgaaaaa gatggtgcat ttaatatgtt aaataatagt
    17761 tactataatt tgcctataaa taatccgtca tataaaaaat tagtagaact tataagagac
    17821 tattctaatt taccaatatt aaatcattgt acagctggta aggatagaac tggtgtgggg
    17881 agtgctataa ttcttatgat tttaggggta tcgagagaga atataatgaa agattatcta
    17941 aaaagtaatg attttgcaga taaagagata gaaagattta tagaatataa gcctaaattt
    18001 aaggacattc caaaagaaaa tttgaaatat atatttggtg taaatgaaga gtatatgaaa
    18061 actgcattta gaagaattga tgaagaatac attagtgtag aagcatattt atatggagaa
    18121 tttaatttaa ataaagaaga aataagaaaa ttaagaaatc aatatctaga gtaaaaggtg
    18181 agtttatgag tttaaatata acagcaagac agataaatat aataaaaata ttgttaaatt
    18241 caaaagatac aattagtggt attgccttaa gtcaagagat aggatgttct tcaaaaacta
    18301 tacaaaatga aataaaggat attaataaac aacttagaaa tggtaaaatt ttgtcaataa
    18361 gaggagttgg ttataaacta gaaggaagtt ttgatgaggt aaatctaaat agcaatctct
    18421 atgatgatgt agatagagta gaatatataa tcagaaaaat attaacctta agtaatgaag
    18481 aaaaaaatac tataaaactt gaagatttag ccgattctat gtatgtaagt gtttcaacag
    18541 taaaaaatga tttaaaagaa gtaaaaagaa tgttggaaaa gtattcaata tcagttaaat
    18601 ctaagcataa acaaggtata tgtgttttgg aaagtgaaga taagatatta aattgtatag
    18661 ttgacttaag caataagaga gataatcaat tgagtttaaa tgatttttta aatgatgata
    18721 taaaggaaag aaaactatta ataaaaaaat tattattaga catattaaat gaaaatggat
    18781 tagtattaac tgatatagaa tttaagagtg tgttaaataa tatattagtt atgttaagca
    18841 gacataagta taatgaaaaa gaatttatag agaattatat agaaaattat aggagcaaaa
    18901 gaagctcaat tttagaaaat gaacaaaaca aagaaattat aataaattca ataaaaacat
    18961 tttgtaaaaa tttaaaatta gctacatcaa tagatataag taatgataag gtatttgaag
    19021 agtttttgta taagcatatt agtagtttat gtaaaaaaat aaagttaggt ataaatcaat
    19081 cacctataat ggctcaagat ataaaaataa aatatccatt tgcttttgaa ctagctaata
    19141 tagctaaaaa gacaatagaa aaagatttga agatagaaat taatgaagat gaagttgcaa
    19201 acatagctct acatatagga ggagcagttg aaagagcatc ttataataat aaagataagg
    19261 ttttcaaaac tataatagtt tgtacttcag gcataggcac atcaatgtta ataaaagcta
    19321 aattagagaa tatatttaag gaaaaattag aaatactaaa gattattcct tcatacttag
    19381 ttgaatatat aaaagttata gatgttgatt ttgtaatatc tactgttcct attgaagtag
    19441 gagatgtgcc agtaataaat atatctccaa ttttaagtga gaaagaaatt agattaattg
    19501 aaaaatatat agaaacagga aatatatacc tagatttaga tataaaaagc ctgtttgata
    19561 gtgaattgtt ttttactgat ttggtgttta aaaggaaaga agaagttata gattttatgg
    19621 caagtaaact tgtacaaaag ggctatatag atgaggatat gaaaaaatct tactttgaga
    19681 gagaaaaaat agcaacaaca gaaataggga atatggtaac tataccacat ggagctattg
    19741 gaaaaatttt tgataataaa atagcaattg gtatattaaa gaagcctatt tcttgggaaa
    19801 tatcagatgt tcgtttaata ataatgttag cccttgataa agataaaata ttagattatg
    19861 aagtaatatt ttcaaaaata tataaaagag tagattctat agcaaaagtt ataagtatat
    19921 gtgaaaatag tagttttgaa aaatttgtaa atttattcaa ttagatgggt agtattgtat
    19981 atacacctgt aaatttggat aatataaaac taaataagat aaaaacgata aatttctctt
    20041 ttaattaaga gaaatttttt gactttcaag gatattaata taaagttaag atataaacat
    20101 aaagcaaata aataaaaaag aggtggcaat atgatttata cagtgacatt aaatccatca
    20161 atagattata tagttaagct agatgagcta aagacaggaa gtacaaatcg tgtaaaagaa
    20221 gaatacgttt atccaggagg aaaaggtata aatgtatctc gcatatttaa ggaacttgga
    20281 aatgataata catctttagg ttttataagt ggttttactg gagaatatat aataagaaca
    20341 ttggaagaaa aagaattgaa gacagatttt ataaagataa aaagtggttt ttcaagaata
    20401 aatgtaaaaa taaaggcgtt aaaggaaact gagattaatg gacaaggtcc aaatatagat
    20461 gatgaagaca ttgatacttt atataaaaaa cttgataagc taaatcaaga tgatatttta
    20521 atattggcag gaagtatacc atctacttta gatgaaaaac tatacgaaaa tataatggct
    20581 agattagaaa aaaagaatat aaaagttgta gtagatgcaa ctaaaaatct tcttcttaat
    20641 gttttaaaat ataaaccttt tctaattaag cctaataacg acgaattaga agaactattt
    20701 ggtgttaaat taaattcaat tgaagacatg gtaaaatatg ctagaaggtt aaaggaaatg
    20761 ggagctataa atgtcttggt atcaatggga aaagatggag cattgttgat tacagaggaa
    20821 gatgaagtgc ttataagtga tgttccaaaa ggaaaagtaa aaaattctgt aggagcaggt
    20881 gattcaatgg tagcaggatt tatatctggg tatttgaata ctgggaaata tgattatgct
    20941 cttaaattgg gagcagcttc aggtagtgca actgcttttt catatgactt agccaaaaga
    21001 gaatacattg ataaattggt aaatgagata tctgtaaagc agttttaaaa tattaaaaaa
    21061 tatatagaaa ggtaattaat atttatgaaa attatagatt tattagatga aaagtcaatt
    21121 aagttaaatt taaattcaaa aaccaaatca gaagcaatag aagaattagt agatttggtc
    21181 gcaaatagtg gaaatttaaa tgataaagaa aactacaaaa aagcaatttt ggctcgtgaa
    21241 gaaatgagta caacaggaat tggagaaggt gtagctatac ctcatgctaa aaattcttca
    21301 gttactaaag cttgtatagc agcagcagtg tcaaaagaag gtatagatta tgaatcgttt
    21361 gacggaagtt tatcaaatct attttttatg atagctgcac cagacggagc taacaatact
    21421 catcttgaag tattatcaag attatctaca atacttatgg atgaagactt tagaaataaa
    21481 cttataaatt caagctctga aaaagaattt aaggaaataa tagataaaaa ggaaagagaa
    21541 aaattcagtg aagaatatca agatgagaaa gttactgaaa aaaatataat agatactaaa
    21601 gagaatgatg ctaataagta tcctaaggtt ttagcagtaa cagcatgtcc aactggaata
    21661 gcacatacat ttatggcagc tgaaagttta aataaaatgg cagaaaacaa aggtgtatca
    21721 ataaaagtag aaactaatgg ttcagcaggt gttaaaaata agcttacaaa agatgaaata
    21781 gaaaatgcaa catgtataat agtggcggca gataaaaatg ttgagatggc tagatttaat
    21841 ggtaaaaaag tcataaaaac taaggtggct gatggtatac acaaagcgga agaacttata
    21901 gacaaggctg taaatggaga tgctccaatt taccatggag gagatggaag tcacaacgaa
    21961 tcaaatgaag aaagtgaaag tggatttaga aaagtataca aacacttaat gaatggtgta
    22021 tctaatatgt taccatttgt tattggtgga gggatactta tagcgatagc ctttttactt
    22081 gatgattata ctattaaccc ttcaaacttt ggttcaaata cacctatagc agcatttttt
    22141 aaaggaatag gagataaagc ttttggattt atgttacctg tacttgctgg atatatagca
    22201 tactctatat ctgatagacc agcgtttgtt gtaggatttg taggaggtgc tctagcaggt
    22261 gatggtggtt caggtttttt aggtgcacta cttgcaggtt ttatagcagg ttatttagta
    22321 gaagggctta agaaaatatt tagtgtacta ccagcttcat tggaaggaat aaaaccagta
    22381 ttgttatacc ctttacttgg aacacttttg atgggaatta taatgacatt tttagtaata
    22441 cctccagtta cagcaattaa taatgcaatg gttggatttt taaatggttt aggtggaact
    22501 tcaaaaatag ttttaggatt agtattaggt ggaatgatgg ctgtggatat gggtggacct
    22561 gtaaataaag cagcatatgt atttggagtt gcatcacttg aatcagggca gtttgaaata
    22621 atggcagcag taatggctgg tggtatggtt ccgccacttg ctatagctct tgcaactaca
    22681 ttttttaaga atagatttac taaagaagaa agagattctg gtaaagttaa ttatgtaatg
    22741 ggattatcat ttgttactga aggagctata ccttttgcag ctggagaccc acttcatgtt
    22801 ataccagctt gtgttggagg ttcagcagtg gcaggagcac ttagtatgtt gttcaacgca
    22861 gctcttcgtg cacctcatgg aggagtattt gttataccag tggttaccca tccatttgca
    22921 tatatattag ctatagctgt aggtgctttg gttggaatga tgcttttagc attacttaaa
    22981 aaaccattaa atcaagaagt atagcaatta aaggatattc aagaacttaa aatatgatgt
    23041 tttataaaaa ttaatatatt gctgaattat tttaaaataa ggattttatg aggctgttat
    23101 ataacgattt gtaattgtta tcttgacagt cttttatttt tatataagta aaataagtgt
    23161 gttttgcttt atttgtattt aaattgtttt taagttagaa tataaagaaa attatatatt
    23221 attttaatat tcac
//
LOCUS       DAEHWO010000060        23072 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEHWO010000060 DAEHWO010000000
VERSION     DAEHWO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23072
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.060"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            244..1080
                     /locus_tag="KNP54_002752"
     CDS             244..1080
                     /locus_tag="KNP54_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0893625.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1433..3010
                     /locus_tag="KNP54_002753"
     CDS             1433..3010
                     /locus_tag="KNP54_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBF0893626.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSNFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            3003..4187
                     /locus_tag="KNP54_002754"
     CDS             3003..4187
                     /locus_tag="KNP54_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBF0893627.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIEKR
                     IL"
     gene            4205..4804
                     /locus_tag="KNP54_002755"
     CDS             4205..4804
                     /locus_tag="KNP54_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBF0893628.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4828..5298
                     /locus_tag="KNP54_002756"
     CDS             4828..5298
                     /locus_tag="KNP54_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0893629.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5657..6403
                     /locus_tag="KNP54_002757"
     CDS             5657..6403
                     /locus_tag="KNP54_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBF0893630.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6464..7138
                     /locus_tag="KNP54_002758"
     CDS             6464..7138
                     /locus_tag="KNP54_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBF0893631.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKAEELADWISEYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLKCMMSCPWSL
                     RYANQK"
     gene            7506..8852
                     /locus_tag="KNP54_002759"
     CDS             7506..8852
                     /locus_tag="KNP54_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBF0893632.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNIIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEKAYSIFYGDILESCNIVLMNRNIDTLESDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8879..10279
                     /locus_tag="KNP54_002760"
     CDS             8879..10279
                     /locus_tag="KNP54_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBF0893633.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENRAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10489..11925
                     /locus_tag="KNP54_002761"
     CDS             10489..11925
                     /locus_tag="KNP54_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBF0893634.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            12269..13213
                     /locus_tag="KNP54_002762"
     CDS             12269..13213
                     /locus_tag="KNP54_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBF0893635.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13382..14314
                     /locus_tag="KNP54_002763"
     CDS             13382..14314
                     /locus_tag="KNP54_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBF0893636.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14419..14886
                     /locus_tag="KNP54_002764"
     CDS             14419..14886
                     /locus_tag="KNP54_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBF0893637.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15130..15984)
                     /locus_tag="KNP54_002765"
     CDS             complement(15130..15984)
                     /locus_tag="KNP54_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBF0893638.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16150..18114
                     /locus_tag="KNP54_002766"
     CDS             16150..18114
                     /locus_tag="KNP54_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0893639.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSYTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18114..18575
                     /locus_tag="KNP54_002767"
     CDS             18114..18575
                     /locus_tag="KNP54_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0893640.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18578..18898
                     /locus_tag="KNP54_002768"
     CDS             18578..18898
                     /locus_tag="KNP54_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBF0893641.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18914..20014
                     /locus_tag="KNP54_002769"
     CDS             18914..20014
                     /locus_tag="KNP54_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBF0893642.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20134..22734
                     /locus_tag="KNP54_002770"
     CDS             20134..22734
                     /locus_tag="KNP54_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBF0893643.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLNKSNDAFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTIFTKGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNKMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         9077 a         2362 c         4065 g         7568 t
ORIGIN      
        1 aatataaaat gtcgattgat tttaaataat taaatataca taagaaataa ttaaatatat
       61 ttcaatgaaa atatgataaa atatgacaaa ttaattgatg acaataaaaa atattttgtt
      121 attgtagtat tatagggtaa attgcaaaat atatacgaaa gtaaaatttt aaatattgac
      181 attaaattaa atatactata ctatgtaagt gtgatgagag aattttttta gaggggattt
      241 atagtgaata taaaaaagat atttaataac aatgtagtag taagctccct agaagatggc
      301 acagaaataa ttgtcactgg tgctggagta ggatttaaga aaaaagtagg cgatttgata
      361 gatgaaaatt tgatttctaa gaaatatttt gttcaagacg atcaaaggga caaatacaat
      421 caaatactta ataagacctc tattgaatac tttaaaattt cagaagaaat tatagaaaag
      481 gctaatgaag ttttaaatac tcaagtgaat gattcaataa tattagcctt aactagtcac
      541 atagaatttg ctgtccaaag agaaaaacaa ggtataaaat taccaaactt aatattgaat
      601 gagacaaaac aactttatag ggaagaattt gaatttggat tatgggcaat tgatgaaatt
      661 gaaaaaagga taggaataaa attgcctgaa gatgaagcag gatatattgc tattcacata
      721 atcaatggtt tggaaaattc tcaaaaagat gaaggtatta atatactaga gttttcaaaa
      781 caagttattc agataattga agaagtacat ggatttaaat tggatgtaaa ttcattaaat
      841 tatactagac ttataactca cttaaagttt tttgttcaaa ggattctccg aaaagaaact
      901 tacaatgata gtgatattga agatatgtat aagttagtga ataaaaatta caataaacct
      961 aaagtgtgta ctgaagaaat tgcagcattg gtattagaca gatttgaata taagattagt
     1021 aaagaagaag aattatattt aatgattcac ataaataaaa taacaaacag tggttgttag
     1081 gattgtaact gataaagcag gcaaaaccta agtcattgag cttaactatt agattaagtt
     1141 ttttgattta ggttttttta ttagatacaa tcaaaataca gacagtgact tttaggattg
     1201 taactggtta agcaggcaaa acctaaatca ttgaatttaa ctattaggtt aagttttttg
     1261 atttaggttt ttttattaga tacaatcaaa tacagacagt ggttgttagg attgtaactg
     1321 gttgagcagg caaaacctaa atcattaaac ttaattatta aattaagttt tttgatttag
     1381 gtttttctat aaatttgatt atgtttttag ataaaaatag gaggggaaaa ttatgaaaaa
     1441 aaataagtta ggtttatgga acttcttcca aatgttagga aaaacgttta tgttcccaat
     1501 agcactactt agtgtttctg ggatgatgct aggacttggg gcaggtttta cagaccctaa
     1561 gatgattgaa atggttccat ttttagggaa tgaatatgtt aacttagttt taaacttcat
     1621 gttaacaata ggattatttg catttaacaa cttgggagca ttatttgcaa tggcaattcc
     1681 actaggatta ttaaaaaaag aaaaagagtt tggtgctttt tcaggattag taggatttat
     1741 agcaatgcat ataggtacaa atttttattt aacaagagct gatttgttag taccagcaga
     1801 acagatgtca actaatggtc aagctatgat tatgggtata caaacatata atacaagtgt
     1861 tttaggtggt attgtagcag gattaattgt ttatgcaata tatgataaag ttagtaattt
     1921 aaagatacca gaatcattag gattctacag tggaccaaga ttagttccaa ttgttagttt
     1981 aatagttatg agtatagttg gattattaat acctattgtt tggccaccat ttttcaatgc
     2041 attccaaagt ttaggaagat ggatttcttc agcaggacca ttaggatatt tttcatatgc
     2101 agtggcagaa agagttacaa ttccatttgg actaaatcat cttgtaacat ctgtattccg
     2161 ttttacacca ataggtggaa ctgctgttat tgatggagaa acgtactttg gtacattgaa
     2221 catgtttatg gcatatgtag aaaataatca gattatacct cttgatttag ctggtaaaat
     2281 ggaacaaggt aaattgatga ttcaatatgg attagctggt gctgcattgg ctatctaccg
     2341 tacagcaaaa ccagaaaata gaaaggcact taaaggactt ttaatatcag gagtgttgac
     2401 agttattata ggtggtataa gtgaaccaat agagtttcta ttcttattca tatcaccagc
     2461 attatttgct ttccatacat ttatgaatgg tctagcaaac atggtacttc catacttagg
     2521 cgtgttgatg ggattcacag gagatttaat tgcatttata agttttggtg tgttaagagg
     2581 aacagctaca ggatggccaa tagcagtatt agtagcagtt ttatattttg caatatacta
     2641 ttttgtattt aagtgggcaa ttattaagtt taatataaag accccaggac gtgaggataa
     2701 agaaataaaa gtatctgaag gaaatggttc aaatttcaaa aatttgtcta catataaagg
     2761 acaacaaatg atatctgctt taggtggtca atctaatata ttatcactag ataattgtgt
     2821 aactagatta cgtttaaaat tacaagatgt atcattaata aatgaggatg caattaaaga
     2881 ggctggtggt atagcagttg ttaaattgga tgagcataca atacaagtaa ttataggaac
     2941 ccaagtgtat tctttaagaa agcagatgga taaagctatg gaaggtcatt tggaggcatg
     3001 taatgattaa ttttgataaa aaagtagacc gattgggtac atattgtacc cagtgggact
     3061 atgtagaaga tagatttggt aagaaggatt tgcttccttt tacaatttca gatatggatt
     3121 tagagtttcc atttgaaata acagaggtgt tgcaggaaag gttaaatcat agagttttgg
     3181 gatacagtag atggaaacat gatgatttta gaaattcagt tacgaattgg tatattaaaa
     3241 gatttaattg tagcgttgat agtaactgga tatattatag tccaagtgta atgtattcaa
     3301 ttagcaaact tattgagatg ttaagtaatg aaggagatgg aatccttata aatactcctg
     3361 catacaatgc tttttatgat gtgataataa ataacaatcg taatattata aagtcacatc
     3421 ttgtaaatag gaatggattc tattcaattg attttaatga ttttgagaaa aagtgtaaaa
     3481 aatctaagat atttatttta tgtaatcctc acaatccaac tggtagagta tggagtgagt
     3541 tagaacttgt taagatgata ggaatttgta agaataatga tgtcaagata atatcagatg
     3601 atatacacat ggatattgta tatgacaata gaatgacacc tatcttaaat gttgcaaagg
     3661 actatttaga ttctgtattc atttgtacat cagcgtctaa atctttcaat ataccagcat
     3721 tgactgggtc atatgtgatt ataccaaatg aaggtattag aaataaattt gaaaatatca
     3781 ctagataccg tgattttgta aattcgccag caattctagc aatattagcc acaatggtct
     3841 gttatgatga ctgcgaatat tggttagatg aactattaaa ataccttaaa gagaatctta
     3901 aatatacgat tgattatata aaagataatt tagaaccatt gaaattggtc atgccagaag
     3961 gctgttactt tgcttggata gatttttccg aacttaaaat aagtggtgag aaattccaaa
     4021 aattattgat ggatattgga gaagttgcta ttatgtcggg gtctgtatat ggtgaagaag
     4081 gtgagtttta tttaaggtta aatgtggcat gttcaagaga aaaacttgaa gatggtttaa
     4141 ataggattaa aaaaactatg gattatattg aaaaaagaat tttatagtag gaagggagat
     4201 agttatggga tatttaaaaa caatggttga tgttatgact actgaaatga atgccataag
     4261 atgtttaata gatgaagcag gaatagaata tgaaagtata gttagtgaaa ttgcaaattg
     4321 tgaaggcaaa gtaattttta tgggtgtagg aaaatctgca catataggta agaaattggc
     4381 agctacattt gctagtactg gtacacctag cttttttgta catgcaacag aggcagtgca
     4441 tggagattta ggaatgattg aaagtaagga tattacaatt ttaatatcaa atagtggaaa
     4501 ttctatggaa gtggtaaact gtataaaata tattaaagca ataggttcta agacaattgc
     4561 atttacttca aacagaaatt cagtactggc aaaagagtgt gattatgctt taatatatcc
     4621 tgcaaaggat gaagcagacc atttaaatct agcaccaaca acatcatcta caattacttt
     4681 ggttttagga gattctattg catgtgcatt atctaagagt agtaattttg gttcttcaga
     4741 tttttataag taccatccag gaggaagttt aggtgagaag ttaaaaacag ctaacaatgg
     4801 ataaaagcaa aaaggagagt agtttttatg ttcaaaatgt ttaaaaaaaa atcaataaaa
     4861 tcacccatat caggaaaagt aatagagtta tctaaaatac aagatggtgt attttctcaa
     4921 aaaattatgg gagagggtgt agctatagat tctacaggag acattgtata tgctccaatc
     4981 aatggaaaga tagtagtagt agcagagact aaacatgcat ttgtaataga attagaaaat
     5041 ggaatggaac ttcttattca tgttggttta gatactgtaa atttaaaagg cgaaggtttt
     5101 gaggcattgg tgagtatggg agaacaagtg aaggaaggaa caccaatgtt gaaaattaac
     5161 cgtcctttga ttgaatcaaa gggtatatca cttattactc cagttacaat aactaatcat
     5221 tcagagtaca atatgaatac atgtaatgta ggcaatagtg ttgaaggtgg gaaagatact
     5281 gtaattgagt ttaaataaag aactaaaata caaggttaat atttataaat acctataaac
     5341 ttatgtttta taagattgat tgtatagatt tgttgtataa aaaagaactc tttaattata
     5401 aattaaggag ttctttttta ttttgtaaat attgtttaga tttatataga aaaacactta
     5461 gtaataaata gaataaataa gtatttatat agctaaaaat ctaaatagtt ttgtttaaat
     5521 atatttttat attttgtaat ttcaaattaa taaataatta gatttgataa acaaaaaata
     5581 aaaatgttga ttatattaat aaactttaat ataatatatt tatgaaaaat gtaaactgtg
     5641 aaatggaggt agtaacatga aaattgaaaa tctttctatt gatgatatta aacgaggcta
     5701 tatatttaat gatgatttaa attgttatag ttgcattaaa tgtacaaaaa catatgaggt
     5761 aggagaaata tataaaatag gtaatagatt ctttgaagct tcaaaagcta ttgaacttca
     5821 tatggaatta gaacatagtg attatttaga gcaattgctt aatagtgatt caaaatacaa
     5881 cacattgact gaaaatcaaa aacaattatt tcaattattt attagtgatt taccagataa
     5941 ggagatagca aaacaggttg gagtatccac atctactata cgccatcaaa aatttatttt
     6001 cagagaaaaa gcaaaacagg ctaagctcta tttagcacta tatgaatctg tatttgaaga
     6061 taaatctaat aaaagtagta ctataatacc aatccatgaa catgctcgaa tggtagatga
     6121 aagatatgta gtaactgaag aagagagaaa acacattttg gatacatcat ttgaaagtat
     6181 gaatccttta aaattaaaag tattttcttc aaaagaaaag aaaaaggtcg taattttatc
     6241 taagattttg gaacaatttg aacgtgggaa gaaatattca gaaaaggaag ttaatcagat
     6301 tttagaatct atatatgatg attttgcaac aattagaaga tatctaattg agtatggttt
     6361 tatgagtaga aataaagaat gtacaaaata ttggttaaca taattaaaat aataaatttt
     6421 actaatgtgt aatgttattt ttatctaggg ggaggagtca aatatgaatg atgaattaaa
     6481 atctatttta tacaataaag gtgtggacat tgttcgcttt gttgatatat ctgaatttcc
     6541 aataaatcaa acgcaaggtt tttctaaagc aattttattt tgtatagggt tatcaaaaaa
     6601 atttattaca gatatataca ataacttacc tacagatagt gatgagtttt tagaaaaaga
     6661 ggagaaagca gaagaattag ctgactggat ttcagaatat attcaaaata aaggatatag
     6721 agcgtattct caatcggaga aaaacaatct agaacatgga tattttgaaa aagcctatat
     6781 taatccagaa atgcaatcag ggattagtcc tttaccacat aagacaatag caaatattag
     6841 tggcattgga tttatgggaa aaaataattt gtttgtaaca gaggaatacg gatgtgcttt
     6901 tagcatgtgt acagtactta cagatgctcc aatttctgtt gaaagatatc ctttgattga
     6961 ttcaaaatgt atggattgta atgtttgtgt agaaaactgc cctgcaaaag ctatacatgg
     7021 aaatgagtgg actttgccag gaaaaagaga gtctattatt gatgtttcaa agtgtttttg
     7081 tgtattgaag tgtatgatga gttgcccatg gtcattaaga tatgcaaatc aaaaataatt
     7141 ttactagaga aggtattaaa ttgaatatta taaaattttt aaaatgtaag attatataag
     7201 atttttcaaa ataaaaattt gtatagaaca ctcagaaatg agtgtttttt tattggaatt
     7261 aaattatatt gatacaaagt ttaactattt taatcattat ataaaatttg tattaaaaaa
     7321 ttaagaataa cttggtaata gtgaaaatat aatgagatta taattgattt ataatataac
     7381 tataatgatg ttgtaaaatg aaaattgtca tttcaaaatt cccaaaaaga gtaaaagtca
     7441 cttcggttat agtcaaaaaa ttttttcagt gaaaagaatt tagatttaaa agggaggaat
     7501 taatcatgga aattgaaact aaaactccgg attggattaa tgtactagaa ttaaacagta
     7561 aaatagatat tactgggaaa tatgatgtaa gtaatattat acaagatatt gtctctgata
     7621 agtcactaga aggttccatt atatattttc caaaaggtaa ttatttattt gagaaaggta
     7681 ttaaaattag tcaacaaata acacttcaag gagattctta ttatggagga gataatcaag
     7741 tatcaaattt agataaaaaa caatcaatca taggaacaac caattttata actcgaggag
     7801 tttctaatat gagtattatt gcattgacag gaacaagtca atgtatcaaa aatattaatt
     7861 tttattatga tagtcatgat atagagaaaa taccgcctaa aaatgtatct gctattacag
     7921 aatatggaga aacacaagga ctatctcatt ttgaacacct gtttatttct ggattttcag
     7981 ggatagggat tgaaattcca tactattcaa ctggcaatga tataattgtt agttcatgtg
     8041 gtcttggtat gaggcttgga gagaagtcaa tgctttctag tagcaagatt tacgaatgta
     8101 aaaatggaat ggagattact actggtgtta gcttaaataa tgtgagaata gaagaaataa
     8161 aagaaatagg tattaataat aaaggatttg gttttaacct gattatgaat cttatggtcg
     8221 accaatgtgg atattgtgga tttatgtttg aaaaaatgtg ctatagccag ataactgcca
     8281 gaattactag atgcggtcag tattataaaa gtgttgatta taatgcttat gagaatatgg
     8341 aagatagaaa agaaaaagct tattccattt tttatggaga tattttagaa agttgcaata
     8401 ttgtattgat gaatagaaat attgatacct tagaaagtga ttcacttaat gaacataaga
     8461 tatatgtaat caaggcaaat gaaacaaaca atgtaatgct aacatgttat gctgaagcag
     8521 ataactttat acaatgtgca aagggcaact tgctgttaga aaatggtgaa aatacttata
     8581 aattttataa tggtgagatt tgttctgtag gaggtgttca aatttctgat atagatgaaa
     8641 aagatttaat caaaataata gagaacactt tgtatataga tgataaaggt aagtatttaa
     8701 tggttcctag attaaaaaag aatactgtaa tatattcagt actagattct acagaagaaa
     8761 taaataaatt acatggtgga atatgggaac agattgatgt aaaagtatta gctggggaat
     8821 ccatgtacta ttataaaaag ataaaagatt aaattatcaa actaggaggt agtgattaat
     8881 ggaagagtct ataataatta aagatataag tggctggatt aatgtacttg attatggaat
     8941 ttgtaatgat gaaacaaaag atgtaagttt taagttgcaa gagattatgg atgctgtacc
     9001 agaagattct attatatatt ttccaaaagg aaaatactta tttgaaagtg gtgttaagat
     9061 taagaaacga ttaaccttat gtggagattc ttatatttta gcgaatgttc ctaaaaatac
     9121 tgctggagta acacagttta cttttaaagg aaagaaaaat cctaaaagtg aaaatagagc
     9181 aatcataaca gcaaaaagtg taagacactg tattaagaac atttgctttt attcagatag
     9241 ttgtgataga gatatgacat ctaatcatga acctccaaca gatggaaaac ctagatttca
     9301 tcataatgta attataaatt atagaaatat atctgctgtt atatgtgaag ataaacaggg
     9361 agaaccaggt cattatgaaa atctatcttt tagtggtttt tctggaattg cacttgatat
     9421 gcctaataat tctacagcaa atgatattac aatttttaca tccggacttg gaattagtac
     9481 aggggaaaat tcaacaattg ctaacagtaa ggtttggggc tgtgttgatg gaatgataat
     9541 ttctactgga acttttataa atggtatgag ggtagaagaa ataaaaaaag ttggaattaa
     9601 aaatattggt agaggtttaa attttattac aaatatcaca attgaccaat gtggatattg
     9661 tggagtttgg tttgattcta tatccaatgt tcagatatca ggaaatatca caaggtgtgg
     9721 gcagtactat tatgatgtaa gctatgataa ttatttaatg ttggataata gagttaaaga
     9781 agcatattct ttattctatg gtaatttatt ggagtcaagt aatatagttt tatcaaatac
     9841 caatgaagat aattgggaag atttcaaaga agataagcat aaggtgtatc ttatagaagc
     9901 acttaaaacc aagaatgtac tattaacatg caatatagat gctactgact ggattgttaa
     9961 gtcagaaaaa ggaaatttaa cgtacaataa tatgcgacaa actgttatat tttacgatgg
    10021 aaaactaagt agtatcaatg gaattggtat atctgatgaa gattatgggg ataaagtcaa
    10081 gataaaaaaa ggaaatatat atataaatag taatgataag gatattaaga tgcataaacc
    10141 agaggtaggt gacattatgt caacaattat taaagataaa agtattcttt ctgctcatta
    10201 tgggggaaca tgggagaaaa ttggtgaaaa aatagagttt ggaataactg tacactatta
    10261 taaattgata gagaaataag taaatacgta gtatttgaat agatgtattt tattggagag
    10321 ttaggactat agttttaata taaatggttt ggtaatagca tggattgaat aatataaaaa
    10381 taatataaaa aattaatttg attatgtaaa tttctatgaa gtagtaaaac tgtgacttta
    10441 gtcataggag gttcaaacta agtaaaaggg aaaggaatat ataatattat ggaaggaaga
    10501 actgggatta aagatggaag atggattaat gtagtagaaa gaggtattaa aaatgatggt
    10561 tcgtacaaca taggtcctgc tttgcaggat attattgatg aaatagaaac agatttttgt
    10621 gtcttatatt ttccaaaagg taaataccta tttacaagtg gtgttaaaat taataaagaa
    10681 attgtattgc aaggtgattc taattcatct acaggtacta cacaatttat aactcgtgga
    10741 gtagaaaata tgagtattat tacattgaca gggaagaaac aatgtattaa aaatataaat
    10801 ttctattctg atagttgtga gatacaggta aataaagaac caccgacaaa aggtaatcct
    10861 aaatatcatt atgagatgat tattaataag aatgaaaaga atgttgagat gaataatgta
    10921 tcagcaatcc tgtatgataa cagtaagaat atgattaaag gtctaggtca ttatgaaaat
    10981 atttatataa gtggtttttc gggtacagga attaggatac catattactc aattgtaaat
    11041 gatattacag tttcatcttg tgggctgggt attgatacag gaatagacac aattatttct
    11101 aatagtagaa tatctaagtg tcaaaatgga atgaggatta gaactggaac tagtataaat
    11161 aatgtaagga ttgaaaaaat acagaaagtt ggtcttataa gtagtcaagt taaggggtat
    11221 gaggggtatg gaagttataa aattaataat attacgattg accaatgtgg gtattgtggc
    11281 ttttcatttg attcaatgaa agatagttat ttttctggta ttataagaag gtgtggtcag
    11341 tattattata atacagatta tgacacatat ttaagtatta aagatagagt agaagaagca
    11401 tattctttat tttatggaaa ttattttaca gaatgtaata ttgatttagt tagtgataat
    11461 aaggataact gggatgatgg cttagaatat aaacataaag tttatgtatt taaaaccctt
    11521 caaataccaa aattaacatt gagatgcaat atagatgcct atgattatat cgttaaatcg
    11581 gtacatggag gaggtaattt aatgttaaaa aataacttta acaattatat atttattgat
    11641 tcatctaatc cagaagttat taatggaatt aattttaatt atcaaaagaa tggaaacttg
    11701 ttaaggttaa ataatggtaa attaagttat aaaaatggaa aggaagaaac agctatattc
    11761 agacctaatt atggtcttat tgtagcatca acagattcag aatgtgaaca aatagaggct
    11821 acctatggag aaaaatggga gaagcttggt tctgaagtaa ttggagaaga aacggtatat
    11881 tattataaac atcatgaacc agataaaaca aaccaaatac aataaaattt gtattatata
    11941 atgatataaa gttttaatat atagtgttta cctttaatgt aatattggta tatttgtata
    12001 gtattaaatt tgttaaaaag taaaattgta gggtgcttga aaatagcacc ttttttagtt
    12061 tcattataaa attagttttg aaagtttagg aataatgtat atttattttt aaagaattat
    12121 aaccttatta aggatatttt aaatgctaga aatgaatcag taaatcatac tggaattatc
    12181 ttaaatgttt tgattaaatt aagtatttag agctataatt atattaaaaa tatattagaa
    12241 cataattata ttactatgga ggttaaatat gatagtaagt gtgagtagaa gaactgatat
    12301 acctgctttc tatagtaagt ggttttttaa cagacttgaa gaaggttttg tttatgtaat
    12361 taatccaatg aatccaaaac aggttagtaa gatagagtta aatccacata ctgttgattg
    12421 ttttgtattt tggacaaagg atgtaactcc aatgttatat gatttaaata aattaagaga
    12481 ctataaatat tattttcact atactataac atcatatgga aaagaagtag agacatgtat
    12541 tttagataaa agaaaggtaa tagattcatt taaggaattg tctagaaaaa taggcaaaga
    12601 aagagtaatt ttaagatacg acccgatttt cttaagtgaa aagtacacag tagattatca
    12661 tatcaaagca tttgcgagtt tatgtaatca gcttgatgga tttacagaaa aatgtataat
    12721 aagttttatc gatttgtata agaaaacaaa atttaatact aaagcattac atataaagcc
    12781 aatagaaatt acagaaatag aaacattatc aaaagagatt tctaagattg ctcataagca
    12841 tgggataata cttgaaatgt gttctgaaga atataattta agtaaatttg ggattggaaa
    12901 aagtaagtgt attgatgata gattaatatc aaaaattata ggatgtgaag tagaggtaaa
    12961 aaaagatagt acacaaagag atatttgtgg atgtgttaaa agtgtcgata taggacaata
    13021 caatacttgc agacattatt gtctgtattg ttatgctaac tttaattatg caaaagtaga
    13081 agaaaactgt aggctttata aggaagataa taaattactc atagatactt taagagatga
    13141 tgcaaaaata agcattagag atatgaagac tattaaagta gataagaata aacaaattag
    13201 tatatttgat taaaataaat atactaatta ccttaatata ttaagaatat agatactttt
    13261 gataacaaaa ttaaacttaa tagatatttt ctatataaga aagatggtca taatatgtca
    13321 atttgaccat ctttttgata taattaaaac acaaataatt tagtaacaaa ggaggcagaa
    13381 cttgaattta ttaaaaaaat atcctatacc tattgcaagt ttgattttat caatttttac
    13441 tttaggtaac ttattacaat cttatagtga atcattacgt aatgtaattg gatttatagg
    13501 atttattttg tatgcaattt atatagtcaa aataatatta cttagaaagg gtgttaaaga
    13561 gcaattagag aaccctttaa tatcaagtac atttccaact ataacaatgg caacaatgat
    13621 atttgctaca tatataaaac cattatcttt agaattaagt attatgattt ggagcatagg
    13681 aattgtgggt catcttgtgt taatagtctt atttagtaag aagttcttag ttaaattctc
    13741 aataaaaacg gtatttccat cttggtatat agtatatgtt gggatagttg cagctagtgt
    13801 tacggcacca gcatttaatc aacttttgat tggcaaaatt gccttttgga taggatttgt
    13861 atcttatata gttcttatac cagtaatttt aaagagagta tggataatca aggaaatgcc
    13921 tgaaccatcc ttaccaagta tagctatatt agctgcacca gggtcactat tattgtctgg
    13981 atatattaat tctttttcag ataaaaataa tgtagtatta tacttgttat tcatattatc
    14041 aattgtattt tatattatag ttttgggata tttaccgaaa ttattaaggt tgccttttta
    14101 tccgagtttt gctgcattta cattccctat ggcaataagt gcaatgggta tgaaactaat
    14161 gaatggttat ttaactaaat caggtcattt tataagttgg atttcatatg cttctaagtt
    14221 agaagagata attgctacag tgattatttt atatgtttta gttttgttta ttatatatct
    14281 tagtaaatct gaaactacat ctaaagctaa ataagaatta ttaaatatgt gtatttaata
    14341 ggaatattga tataaatata tgaagataag ataaaccata gaaacttaat ttagcttaat
    14401 tttattggag gaaaacaaat gaaaacaaaa gaagaatatt taaaagaagt tagaaacata
    14461 tcagaagaat actttagaaa aggagagttt ttttgctctg aagcagttct ccagacaata
    14521 aatgatgctt taggccaacc tttaagtcca gagataacta agttagcatc aggatttccg
    14581 ataggacttg gaaaggcaca atgtctttgt ggagcaatat ctgggggaga gatggcttta
    14641 ggtatagtat atggaagagt tcatggtgaa gctatgaatc caaagatgtt tgagcatgct
    14701 aaaggtttgc atgattatat taaaaaagag tatggtgcaa catgttgtag agctattaca
    14761 aagaaatggg atggtgataa ctttatgtct cccgaaagaa aagagcactg tattaaaata
    14821 acaggtcaag ttacagagtg ggttgcagat aagcttatag aagatgaaaa acttaatatc
    14881 aaatagtgta atattagttg gtgaatttat aaagttaaat ttacttatag tataagatac
    14941 ttgatattct cgtattgata gaaaaattta tagcatatgt atttaatgaa atatacttat
    15001 atttagagtg tggtttaatt tcataaatac atatgctatt attttaagta tataagcaaa
    15061 tttatttaaa taaatagaaa cagttaattt atatgtacaa aactatatat gattagtgta
    15121 aataaatacc tattttataa tactcaacat aaagacacca gacatgatta gtattatacc
    15181 aataaaaata gcaagccatt cttttttgtt cttcttttct ttaaaaaata taatccctcc
    15241 taaagtggct actatcacac aactctgaga gatagaaaaa cttattgtaa ctcccaatgt
    15301 attagtcgtt atgaacatac ctaaatttgc tattgaccac aatataccag taattaaatt
    15361 gaataaaaca ttttccctat atacaatctc tttagaaaaa tacttgacaa taatagatga
    15421 agttatcaac ataccaacag attgaggtaa tataattcta tatccttcaa ttaaaaatat
    15481 ttgattagtt acaacatata atgataaaaa tagagatgat aataatacaa ctccaacaca
    15541 ttttaacata tttttatctg tagatttttt agtttgataa tttgtgagaa gtataccaag
    15601 tattatacat aatattgata aagaaccaat cagtaacatt ttagaactgg tccattcatt
    15661 aaacaagatt acagctaata atgtcgtaaa agttaattgt gaaccatttg aaattggcat
    15721 tactttagat acactagcaa tttgaattgc tttaaactgc attaattgtc ccaaactcca
    15781 gaatatgcca gaaatcatac ttatacaaaa tgaaaaaaat gtaatttcag gatgtataac
    15841 cagagttatt atagtggaaa atataaacgc acttatggat gtacctaaaa gctgttcatg
    15901 aggagaactt ttctttagat ttgcaactat gggcatcaat ccccatccca ttacaggaag
    15961 taaagcaata attattgtca gcattaaact atttcctttc atattaaatt tagacagctt
    16021 ttaatttatc atctaaaatt aaagtgttca atacataaaa attaccgtat ttaatcagga
    16081 aatattagta gttttttaga aaaacatttt ccattaaaat aaagacaaag ggaaggagta
    16141 aaattgaaaa tgttaactga tatgattcaa aatcgtgaaa ttaaaataat aaagttttta
    16201 ttaaaagaag gtcatacaac tgtaaaagca atagcagatg atttagatgt ttcagaaaaa
    16261 acagtttcaa aatctcttaa agaagtagaa gcagtgctta aaaagatagg tctttcttta
    16321 ataagaaaac ctaagatagg tgtttatatt gatggagatt taaaaaaaat acttccttac
    16381 ctagataata aaggaagtca aattcctaca accagagagg agagagttat ctatatatat
    16441 tcagtacttt taaagagtaa tgattatatt actatacaac aactttctga tgaactatat
    16501 ataagtcgtg gaactattga aagggattta gcagaagttg aaaaactgct aaaaaacgaa
    16561 gggatttcca tatataagaa acctagtaag ggaataaagt taaatataag tgaaagagat
    16621 aaaagacaac ttactgctaa gtttatacat aaattttgga gtagaaactg gtatattaag
    16681 caagagcaag aaagctttta tcaagcattt gaaaagatac aagcagatgt aaatggtatt
    16741 ttttcggaag atgatttatc aataattatt gatattctta ggaatttcag cagagaaaga
    16801 aaatttgagt tctctgatta tgaatttcag tcattagtta ttcatttggc aatagctgta
    16861 gagagaatta gaaaaggcga atatatagaa gaaagtttgt atactggtaa tatagaaaat
    16921 aatcaaatgt caaataccaa ttatttagca aaacaattag aagaaaaatt ttcaatatta
    16981 ttaccaaaat ctgaaattgg atatataaat ttacatttag tagcgtctga ccaacataga
    17041 gatactaatg aactaaaaaa tacttcaact aatccttgtg agacaagtac aaataatata
    17101 tcaaatcttc gggaaattat aaaaaataca ttgtatgaga cagcttatga caaggattta
    17161 attgatggat taacttcaca tgtacattca tcaataaata gactgaaata tggacttagt
    17221 attaaaaatc catatgtaaa tacaatcaaa caaaactttt ctttatcatt tgagcaagct
    17281 ttagatttaa agaaagtaat tgaatttata tatgatatta ggataaatga tgatgaatgt
    17341 gcttatatag cattacattt tgaagctttt agagaaagaa tgaaagaact tccacaaaat
    17401 attagagtaa ttctagtatg cagtacagga ttaggttcat ctaggttatt gtctgcaaga
    17461 ataaaaaaat actttccaat gataaagatt gaaaaagtac tttccgtaca agaattagta
    17521 tccagtaaaa ttgatgcaga tttagtaata agtactattt atttagagtt agaaacaatt
    17581 ccaaccatag tagttagtcc tattttaaat gaaagtgata taagaacctt ggaaagaaat
    17641 atacaaaatg tttcaagtta tacttctaag aagtataaat ctttcagaaa cttaatcttt
    17701 gaagaaaata tattgttgaa tattgaagct tcaaactatg aagatgcaat taagtatata
    17761 acagataacc taataaaaaa aggttttgca aaagaaggta tagctaaaag tgcaattgag
    17821 agagaaaatt tatcttacac ttctttccaa tcaatagcta cacctcatgc taatcctagt
    17881 tatattaaaa aatctaatat atctgttgca acgttaaaaa atcctattac atggggaaat
    17941 gaaaaggtgg aagttatttt ctttatttca ttagaaaatg acaaaaacct agagcttgat
    18001 gaaatatatg aagtttttta tgacttcatt gacaataaaa aaaatataaa tgacatatta
    18061 agtgcaactt ccacaaagga agtgtacgat ttgctagtgg aggagagtat atagtgaaaa
    18121 tatcagatgt attgaaaaaa gagcaaattg tttttaatct tgatacaaat acaaaggaag
    18181 aaacaataaa aaaattaagt agtatatttg ttgaaaatgg gattgtggac aatgaagaag
    18241 aatatgttaa gtctgttttg gaaagagaag aacattcaac tacaggtatt ggtaatggta
    18301 ttgctattcc tcatgggaaa agtaatgctg tcaaaaaatc ttctataata tttgcaaaga
    18361 ctaagcataa gattgaatgg gatgctttag atgaaaaacc agtagatagt attttcttat
    18421 tggctataag caatattgat aaggatagca atcatcttgt actattatct aaattagcaa
    18481 ctaaacttat ggatgatgac aatgtagatg cactaaaatt agccaattca gaacaagaaa
    18541 taatcaatat atttagtgaa gaaggagaga tgtagaaatg aaaagaaaaa ttatagcagt
    18601 tacagcatgt gcaacaggag ttgcacatac atatatggca gctcaagcgt taaagaaagc
    18661 ttcaaaaaag atgggtcacc ttataaaagt tgaaacacaa ggagctacag gaatcgataa
    18721 tgagttaact acaaaggatg cacaaattgc agaagtagta atatttgcag tagatactaa
    18781 agtcagaaat gctgaacgtt ttgagggaaa agaaatacta gaagtaccag ttaatgcacc
    18841 tataaaggat gcagagaaag taataaatga tgcactaaag ttaattgaca ctaaataaat
    18901 ggagggaaat gtaatgttga aaaagatagt ctctgagtta aaaaagcatg tcttaactgg
    18961 aatctcatat atgattccat tagtaattgc aggtgctatg ataatggcga tatctcgtgt
    19021 aggtggttct ttctataata taccagatat atgggatgct aaatatgcag aaagtgctag
    19081 tagtattgtt agattattac atgatttaga tgggtttgga ggtactgcat taggattaat
    19141 gtttcctgta attgctgcat ttataggatt ttctatagct gataaattag ctattgtacc
    19201 aggtcttgtt ggaggtatga ttgctaaaga tataggtgca ggatttttag gagctttggc
    19261 agttggtctt atagcaggat atacatgttt gtttattaaa aatcatgtta aattaccaaa
    19321 atcagcagct tcaatagtac caatatttat agtaccagta tttgggacat taatcactgt
    19381 tgtattaatc aattatgtga taggtatacc ttttgccaca ttaaatactg gattagaaaa
    19441 ttggttaaat ggattatctg gtacaaatca gatactaatg gcagctatta taggggctat
    19501 gatggcagtt gacttaggtg gaccagttaa taaagcagct ttaacaacat cacttgcatt
    19561 attaacaagt ggaatttatg cgcctaacac tgctgcaatg gtaggaatag ttataccacc
    19621 actaggattg ggacttgcta ctatactagc aaaacaaaaa tataataaac agttacgtga
    19681 agctggaaaa tcatctctta taatgggttt aattggagta agtgaaggag caattccttt
    19741 tgcggtagaa tctccattaa aagtaatacc ttcatgtgta attggaacag caattgcttc
    19801 agctatggca gttggtttag gttcagtaaa tgcaactcca attagtggat tttatggatg
    19861 gtttacagta gagaattggc caatgtatgt gttatcaata gcagttggaa cagtaattgt
    19921 agctggatta gttatagtat tgcgtggaaa tccagtgatt gaggatgatg aatttgaaga
    19981 tgatgatttt gatgaagcag agtgggaatc ttaaaattta ataactattt aagacgtgtt
    20041 ataagctata ttcaatatga atcttatact aaataaagtg ttaaacattc agtttagact
    20101 taaatataaa agataaagaa cagaggagaa taaatgataa aagcacatat tgttaatcat
    20161 acacactggg atagagaatg gtattttact tctggagatg cattagtact tagtgaacaa
    20221 ctatttacag atgtaattga tgaattagaa cgtaatccag atgtaagttt tgtacttgat
    20281 ggacaacttt ctattttgga tgattatgta caattacaca aagaaaaaat agaaatcatt
    20341 aaaaagttaa taaaagaaga tagactacat attggaccat ggtttactca aactgatgca
    20401 ttctttgcta gaggagagtc tattttaaga aacttaatga ttggaatttt tgaaagtaaa
    20461 aagtatggta agtatatgaa aattgggtat ttgccagata catttggatt taatgcacag
    20521 atgcctatac tattaaagca tgtaggtctt gataatatat tcttttggag aggtatacat
    20581 cttggtaaac aggttcaatc accatatttt aagtggaaaa gcttaaatgg agaaagttat
    20641 atatatgcag taaatatgcc acatggatat ggaactggta tgcttttaga gccttcatta
    20701 aagtatgtta atggacgctt agacccagct attgatttta ttaaatcata tactgatgta
    20761 gatgaggtgt taataccttc tgggaatgac cagttaaata taataggtga tttcaaaaat
    20821 aaaattaaag cgattaatga tatcggaaag tattcatata taacgagttc atatcaagag
    20881 tttttaaaat atataaagtc catagaatca ctagaaagct atagaggaga atttagagaa
    20941 cctgtattag caagaataca taaatcaatt ggttctagta gaatggatat aaaattagca
    21001 tgtgataaac tagaaaacaa gctgattaaa agaatagagc cattattagt aattgctaaa
    21061 aagagtaaaa ttgaaataag caatcagtta cttataaata catggaaaaa acttttggaa
    21121 ggacaagcac acgatagttt agctggatgt gtaactgata ctgtaacaga tgatattctt
    21181 caccgtataa gagaagcaaa tgaaatatgt gacagtattg aaaatactat tgtaaaaaag
    21241 atttcagaag ggcttaaatt atctaaaaat gatattttag tatttaatac agaagctaag
    21301 cgttttaatg gatataaaga gatacaagtt gtaagtgata gtaaaaatat ttattttaaa
    21361 gataatttag atgctactat aattgaagaa acttatgtaa aaccgagaga aaatgtatta
    21421 gaagaaacac ctgctggtaa tatatttatt gaagaaccag gatattatat attaaaagta
    21481 agaataaatg tacagcttcc tgcacttggt tataaagttg ttagttttga atcaagtgat
    21541 aaagaaatgg tgtcacttaa taaatctaat gatgctttta tatctaatga taattataag
    21601 ataatatatg aagatggaag cttaaattta caacttaaag atggaactta catatcaaac
    21661 tttttaacat taaaagatag tggtaatgca ggtgatacct atgacttttc tccactaaaa
    21721 aatgatgagg atataaaact ttcgtttgat aaagtgtata cagaaaaagc tttaggatat
    21781 gaaaaaatgg tggttaaagg tactacttta ctaccactta cgttagaaga tagaaaaaac
    21841 aaatatctta atgggaaatt aaatgtaaaa gtaagtattg tcttatccaa agaaaatcca
    21901 ttgatggatg taaaactttg tgttgataat acgatatata atcatagact acgtgttcat
    21961 ataaaaactg atataaaaga taataaaaac atagcatcat tgccatttgg atatataaca
    22021 agagaaaatg gagttttaga caactgggaa gatatttaca gtgaaatgcc tatagattta
    22081 gaacctttgg aaagtaatat tactctaaca aaccaaaata gaagctgtac tatatttact
    22141 aaaggaataa aagagtatca acatattgaa gatgaaattg cattgacctt acttgctact
    22201 acagatgaac taggaaagcc tgatttatta tatagaccag gacgtgcttc tggtgataca
    22261 actaaaaaag gtcacataag aattaaaaca gataaagctc aaatgcttaa gaaattagaa
    22321 ttttcatttg caatatatat ggattctaaa tcatttgatg aattggaaat tgcgaattta
    22381 acccacaatt atctaaggga atgtgtaaat tatcaattac aggattacaa tttcttttta
    22441 tatcgtatag ataataagat tcaaaaatca attgtcaata aaactgtaag tagagaatta
    22501 gaaataatat ctttaccaga aaactatctt atatcagcat gttatccttc ttattacagt
    22561 aaagataaat ttataataag agtggaaaat ccaagtagta ataaaatgat attggatgag
    22621 caaatattta aaaatagaaa tgggaaaatt gtaaatgcaa tagaagatgt agaagaggaa
    22681 caggtatatg aaatagcacc ttttgacgtt atttcaatat tattggattt ataagtgtaa
    22741 aagtaagttt attgtttaaa gtctgacaga tattaatctg ccagactttt taatttgtat
    22801 aaatttgggt aaatattaat gaatggtttt agtatttaag tatgaattta gtatttaata
    22861 tagaatttat tgaagtagaa taattagttt aacaggataa gcagtttaaa taaagaatta
    22921 ttatattaga gtgattttat atataattta agataataaa attttaataa aatgagttaa
    22981 agattgtata ttaatagagt tgatgtagtt acaaaaaagt taccaattgt tatgtattta
    23041 caaaactgat atattaatta cataaaatct aa
//
LOCUS       DAEHWO010000061        23014 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEHWO010000061 DAEHWO010000000
VERSION     DAEHWO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23014
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.061"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(257..1306)
                     /locus_tag="KNP54_002771"
     CDS             complement(257..1306)
                     /locus_tag="KNP54_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893644.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKEDMSEMKQEMTVMKEDMSEVKQEINVLKGDMSEVKQ
                     EMIVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEMTVMKEDMSEVKQEI
                     NVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITV
                     MKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMK
                     EIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELA
                     TSKNWSDIVKLKSVK"
     gene            complement(1536..2621)
                     /locus_tag="KNP54_002772"
     CDS             complement(1536..2621)
                     /locus_tag="KNP54_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBF0893645.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(2657..3970)
                     /locus_tag="KNP54_002773"
     CDS             complement(2657..3970)
                     /locus_tag="KNP54_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBF0893646.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(3971..6262)
                     /locus_tag="KNP54_002774"
     CDS             complement(3971..6262)
                     /locus_tag="KNP54_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBF0893647.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGKTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(6252..7046)
                     /locus_tag="KNP54_002775"
     CDS             complement(6252..7046)
                     /locus_tag="KNP54_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBF0893648.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMTKALVVRMYNSIGGECDGK"
     gene            complement(7085..7531)
                     /locus_tag="KNP54_002776"
     CDS             complement(7085..7531)
                     /locus_tag="KNP54_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBF0893649.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(7603..9009)
                     /locus_tag="KNP54_002777"
     CDS             complement(7603..9009)
                     /locus_tag="KNP54_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0893650.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     IRGTIKNRMEGHKWNSLY"
     gene            complement(9027..10397)
                     /gene="hydA"
                     /locus_tag="KNP54_002778"
     CDS             complement(9027..10397)
                     /gene="hydA"
                     /locus_tag="KNP54_002778"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBF0893651.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKIAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(10530..11717)
                     /locus_tag="KNP54_002779"
     CDS             complement(10530..11717)
                     /locus_tag="KNP54_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBF0893652.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            complement(11844..13058)
                     /gene="dpaL"
                     /locus_tag="KNP54_002780"
     CDS             complement(11844..13058)
                     /gene="dpaL"
                     /locus_tag="KNP54_002780"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBF0893653.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(13421..14092)
                     /locus_tag="KNP54_002781"
     CDS             complement(13421..14092)
                     /locus_tag="KNP54_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0893654.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(14175..16391)
                     /locus_tag="KNP54_002782"
     CDS             complement(14175..16391)
                     /locus_tag="KNP54_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBF0893655.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(16394..16864)
                     /locus_tag="KNP54_002783"
     CDS             complement(16394..16864)
                     /locus_tag="KNP54_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBF0893656.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(16926..18320)
                     /locus_tag="KNP54_002784"
     CDS             complement(16926..18320)
                     /locus_tag="KNP54_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0893657.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(18393..19754)
                     /locus_tag="KNP54_002785"
     CDS             complement(18393..19754)
                     /locus_tag="KNP54_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBF0893658.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(20051..21373)
                     /locus_tag="KNP54_002786"
     CDS             complement(20051..21373)
                     /locus_tag="KNP54_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBF0893659.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(21729..22769)
                     /locus_tag="KNP54_002787"
     CDS             complement(21729..22769)
                     /locus_tag="KNP54_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893660.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT         6853 a         4645 c         2531 g         8985 t
ORIGIN      
        1 taaaattttt atgttctcat tgataaaatt ttacttattt caagcgttct attagatttt
       61 atcatctaaa ttttaggttt tatttttata aattaattgt atttacataa aaaaaaagac
      121 ctaaaaacaa atttttaacg gtcttttctc aattttttat tttcatttct aaaatttata
      181 ataaatagta agaacactat aaattctttt atataaaatt cttagtttgt ggatgataaa
      241 ttagtgaatt aaaatactac tttactgatt ttagtttgac aatatcactc caatttttac
      301 tagtggctaa ctctactaaa tttaagtctc ttcttatttc agctatatcc tcttttatag
      361 aattagtgtc accttttata tatgctatgt tatgttctat attatcatga gtagctttat
      421 ttatttcaga attatgtaat aaacttccta aaatattatt ctgttctatc tgtatctctt
      481 tcattgattt atcttcacat tctagactat caatcttaat ttcaattcca tataattttt
      541 catttgctat ggatacctcg tccttaattc cattcatatc ttcattaatg ttatttattt
      601 tattttgcat aaagtttact tctgatttaa cttcggaaac atcttctttc attacagtta
      661 tttcttgtct cacttctgac atgtcttttt tcattacatt tatctcttgt tttacctctg
      721 atgtatcttc tttcattacg gtcatttctt gtcttacttc ggacatatct tctttcatta
      781 tatttatctc ttgtcttact tcggacatat cttcttttaa tacatttatc tcctgtttta
      841 cttccgacat atcttctttc attacagtca tttcttgtct tacttccgac atatcctctt
      901 tcattgtatt tatctcttgt cttacctcgg acatatcctc tttcattata tttatctctt
      961 gtcttacctc ggacatatct tctttcatta caatcatttc ctgttttact tctgacatat
     1021 ctccttttaa tacatttatt tcctgtttta cttccgacat atcttctttc attacagtca
     1081 tttcttgttt catttccgac atatcttctt ttaatacatt tatttcctgt tttacttccg
     1141 acatgtcttc tttcattaca gtcatttctt gttttacttc cgacatatct tcttttaaca
     1201 catttatttc ttgttttact tccgacatat cattttttat gctaactaca tcttcattta
     1261 tagtatataa taactctaaa atcttctctt gcacttgcat caccatccct attaattatt
     1321 ataacatttt acacaaatgc tatacaatgt taacatatat atcagaatta ttaaaatttt
     1381 aattaaacaa aattgattca ctttattact tcaaaactaa ttaatatcta aaataactac
     1441 aaataaacaa aaataaggtc aacaacaaaa aaggcttatc tctttgagat agcctttctt
     1501 atttttattt aaaactttgt tttttataaa ataatctata cattcagctc tgaacatgaa
     1561 atttttcttc caagtgcttt tggtttacaa actgatatac aaagtccaca atatctacac
     1621 tcttcttcat tcaattccat cttatcattc aattttctcg cttgatatgc acaaactctc
     1681 tcgcacatct tacatttagt acatttttct tcatcataag taaactcaaa gctaagtctt
     1741 tcattaacat ctcccatatg attatgtact ataccacaag cattttctat agtattatat
     1801 cctaatctat taagattaga ttttaaatca tcatgtattt tagatattac ttgtgcacct
     1861 tttaaaatta ctactgaaca tataccaaca aagtcagcac ctgccataat catttctaag
     1921 gcatcatctc cacttacaca tccacctaag ccaattattg gtatattaac ttgttttttt
     1981 atttcatata ttctctgtaa agttattggc ttgatagttt ctccacttaa atatcctatt
     2041 ccatttccac ctaataaagg ttgccctgtt tctatgtcta ttctaaatgc tggtcctaca
     2101 gagtcacaag cagttattgc atctgctcct gcttcttcta attttttagc aaaatcgcct
     2161 atctcatcta tcataggagg aagtttaact attacaggta tatttactct ttcctttgca
     2221 tctttaagca ttggtatcaa atctctatag tcataagata ctaattcaat aaagtcagct
     2281 cctgcatttg caactttctc tactaattcg ctactttctt caattgtatg acctattgaa
     2341 gctatacaga cagtcccatc tcttttcatt tgtggtattt caaaatctat ccattgctct
     2401 ggctcaaaat ctgtccattt ttcattattt aaaagagcat tagctgtatt tctaaccata
     2461 tgtggtgctg gatttatagc tctttctttt cttatagtct tagtcacaac tgcccctgct
     2521 cctgcatcac ttaatatctt gcatccagct gcactatatg ttaatggtcc tgaacctatt
     2581 ataagtggtg attttaattc tttacctaaa aaattataca ttatctgctt ccccttttca
     2641 tatatattta cattcgttaa aatttccaaa attcacaagc aacttctttc atttctttaa
     2701 caatagcttt tttatctaaa tcaactaact gtttttcttt taaaatatgt ctaccatcta
     2761 tgtatacatt tgatataaat tcttttttac cctgaactac tatctggtca aatatattat
     2821 caagagtcac aggagtttta aattcatctt ccataactat tatatcagcc ttattaccaa
     2881 ctgctatttt accagaattt tgaagtccta atacataagc accatgctct gttgccattc
     2941 taaatactaa atttgctggc attactgatg catcttcttc aactgattta tgcattaaaa
     3001 atgcacctct cataacttca aaaaaatcat ttatatatcc atcagtaccc agtgccactt
     3061 ttatgccttt tttaatcatt tttggtactg gagaaaaacc tccacctact tcacagttac
     3121 taagaggcat atgaaccact tttacgcctt tttcttttaa tatatctatt tcttcatcat
     3181 ttacttttac acactgagat gctaatacag tttcatccaa tatatctaaa tcattatagt
     3241 agtcaactgc ttttttgcca aagtgttttt cagcatagtt tggctcatat atactctcac
     3301 ataaatgaaa ttgcattggt gcatttaatt tttttgcatc ttctttagct ttcttaataa
     3361 atctatcaga acatgtgaag cttgtatgtg tacacattat tccatttatt aatttactat
     3421 tttctctact ccactttatt aaattagaat tttcatctaa acatctaagt ccattttcaa
     3481 agcttattct ttcacaactt tctaaggata aaatcgcttt catgcctatt tcttctagta
     3541 tttttccttg ctcaattaaa gttccttctt ctgtatttgg agcttctagg gtatcacaaa
     3601 aagctaccac accagattct ataagttcta ttgctgatgc tttagttgtt gccttcactt
     3661 cttttaatcc aattctattt tctataaatg gccaccaata gtcatttaaa aaaccttcaa
     3721 agtcagtaaa atgtacattt gccggtattc ccctagaaag aactccatat tgatgcatat
     3781 gaccattgac gaatcctggc attattatag catctgattt atctattatt tcttcaatat
     3841 ttttatattt tatttcaact tcttcatttg gcaatatatc ttttataatg tcattttcta
     3901 ctacaacagc agaatttgta tatatttcat cagcagaaga tattaagtat ttacttttaa
     3961 tagcaatcat ttatttacct ccctgattta attttttcat ggccatataa actttctcag
     4021 aagttatagg aagttctctt atacgaactc ctgtggcatt gtatattgca tttgctattg
     4081 ctggtgcagg tgtatgaata actatttctc ctaaagattt agctccatat ggacctgttg
     4141 gctcataatt atctacaaaa tcaacaatta tgtttcctat atcttttttt gttggaactt
     4201 tgtattgtaa tagattagaa gtttgaagct ttccatcaga accatgtcta gggtcttcat
     4261 acattgcaag ccctatacct tgagttacac caccttcaac ttgtattcta gcaagtgcag
     4321 gattcataac tgtaccacaa tctgtagaac aagcataatt tattacttta aactcccctg
     4381 ttgttttatc taactctatt tcagcaaatc ctgctaagaa tggtttagca ctctcttgta
     4441 taccataaga ttcagatgaa tataaaactt cttgatttcc accaccaaca gattcttttc
     4501 ctaattcact taacaaaaca aacttctcta catcttcact ataacaaact ctgtcttcat
     4561 atagtattaa atcatctatt ggtaaatcga gtttcttctg tgctactttt aatatctttt
     4621 gttttaaact ttcagcagat tttattgtag catttccagt tacataagta gtacaagaag
     4681 cgtatgcacc agtatcatat ggacacatat ctgtatctcc tgtataaacg gaaattctat
     4741 caatagatgt attcaatgct tttgcagcta tttgtgcaag tattgtgtca gaaccagttc
     4801 ctaagtctga agacccagaa aacaacttat aagttccatc ttcatccatc ctcatattta
     4861 ctattgccat gtctatgttg gctataccag aaccatgagt tcccacagac attccaacag
     4921 ccctcacctt attgtttcca atatccctaa cagggtactt ttcatcccat ccaataagtt
     4981 ttttacctct aattatacat tcatcaagtg cacaacttct tattggaaaa ttcattattc
     5041 cgccttcagt ttgttttttt ataatattct ttaactttat ttctgttggg tccatattaa
     5101 gtttatgcgc taattcatca attgcacaat caagtgcaaa tgtaccttgt gttgctccat
     5161 atcctcttaa tgctcctcct ggaactaaat tagtatatac agttttccca tcaaatttta
     5221 ttgcaggtac attattatat gttggaagta cattatgacc tgattcagag caaactgaag
     5281 gtccattatc gccataagcg cctgtattgt tcaatgcttt catatctata gcttttatgt
     5341 ttccttcttt atctgcccca atttttatat caaaaaacat ctgatgtcta gtattagtca
     5401 ttgcaaaagt ttcttctcta gtataaatta gttttgctgg tctttttgtc atccaagtta
     5461 caaatgatgc atatatctct gttacagcta tgttttttcc accaaaacct ccacctattc
     5521 ttggttttat tactctcact tttgaaagag gtattcccag tgctttagaa acctgtcttc
     5581 tcatatgata agctgattgg tttgcagaag ttactactaa tctgccattc gtatctatat
     5641 acgtataagc tctatgagtt tccatcatac aatgggcttg tgattgagtc atataagaat
     5701 gttctactat tacatcactt tctttaaact ctttttctac atccccttta cccatttttt
     5761 ctctcgatac aatatttttt gtagcatcca atccaaaatc aaatggacaa aacaaatcat
     5821 cttcttcatg gattaaaatt ttatttcctt ccgattctct tgcatccaat ataggagtca
     5881 ttacttcata ttcaactttt ataagtttca tagctttaat agcagccctt tcatcttcag
     5941 cggctattat agcaacttca tctcctacat atctaactac gtcttcaagt attaattggt
     6001 catgaggtga tgcttctgga tatgactctc caaccattga atatctataa tttggaacat
     6061 ctttgtaagt gaatatgttt actacacctt ttacctttaa tgcatttttt atatctatgt
     6121 tttttatctt cgcaaaagca tgtggacttc taagaagctt aattgttaaa acatctttat
     6181 gaaaaattaa atcttctgta tatattggtt ttccagtaac aatggcttca ctatctattt
     6241 ttcttacctc tttatttacc atcacactca cctccaatac tattatacat tctcactact
     6301 aaggcttttg tcatatcttt tctgtattct ttacttcctc ttatattact tccaaatgaa
     6361 agttcttcac ttgatacttc accagctttt tctatatcat tttctaaact taatatttca
     6421 cttgctttat aggcaatttt tgctcttctt ggtctagcgc ctatcgcaat tttataaata
     6481 cttccttctt ttaacattgc tccatttaat actgcaaaat cacctgtaca ttttcttata
     6541 gaatcaaata cacctatagc atctttttta ggtaatataa cttctattaa tatatctttt
     6601 tcaagctcat tttctaaaaa atcagctaag ttcataaccc cttttttata taacttaacc
     6661 tttgcatcta ccactagtaa tgaaggtatt aaatctgaaa atccatactt agcaaatacg
     6721 ctagctccta ctctagctcc acttctaaat tgaactccta ctatattaga aacagcgttt
     6781 gaaattaccc cattacagta atttttaata accttattta attctaaagt tcttaaactt
     6841 gtatctgctc caattaatat gctatcatca gtttcattta tataatctaa agctaagtct
     6901 tttaaatcta ttgctgaacc aatattttta ctacctagtt ttaaaaatcc acatcctcca
     6961 agtattatgt tgttttttct tgatattagc agttcataag cttcatctaa actttttgga
     7021 actacatatt cctttatagt tatcatactc tctccccata tcaacttaat tttcacttaa
     7081 aagtctaagt gtttaaatat ttatgtattg ctcttaattg acctttatat cctgtacatc
     7141 tacaaaggtt accatttaca taatctataa cttcttcttc tgttggattt tgaagctctc
     7201 ttttcattgc caagaccatc attataaatc caggagcaca aaatccacac tggtcagccc
     7261 cttcgtctgc aagaaaatct ccaaacttct ttgcttcatc caagacaccc tcaagtgttg
     7321 taatatgctg accttctact ctagcagtaa gataattaca tgaaagcacg gccttgtcat
     7381 ttaccatcac tgtacataac ccacatgagc ctgtatcaca ccctttttta acacttacat
     7441 atccattttc tcttaatgta tctgctaaaa aatcatctgg tcttatactt aattcttttt
     7501 ctttattatt tatggtacat ttgataatca aataaatcac ctcaaaactc atatttttaa
     7561 gctaaagttt tactatactt ttttatgaat aaattacatt tattaataaa ggctattcca
     7621 tttatgacct tccattctat tttttatagt tcctcttata caaagtctct cagctgtatc
     7681 ttgagcatct tttaatgctt tctcttcatt agctgtcaat atttttgaat cttccattat
     7741 tatatttcca tctactataa cactctctat atttttcata ctagaagaat atactaatgt
     7801 agataccgga ttatgcatag gtatcgcttt tggtgaaagc attggattaa atattagtaa
     7861 gtctgctttt ttacctatct ccaatgaacc tatctcatct tccattccaa tagctcttgc
     7921 tccatctata gttgccaact caagaacttt ttctgccgac attgctaatg ggtcacactt
     7981 attaacttta tgttgaagtg ctgttaattt cataagttca agcatatctt gagagttatt
     8041 actagcggct ccatctactc ctaaactaac tgttattcct tttttaagca tttctggcac
     8101 tggtgcaaca cctgaagata agtacatatt acttgctgta ttatgagaca ctttcatatc
     8161 gtatttttta gtaagttcca tatctttttc agttagatac acacaatgta ccataagcac
     8221 atttggtcca agtattccta atttttctaa aacatctatg tcatattgcc catgcaattc
     8281 ttttgctgct tctctatcaa aaggagtctc tgatatatgt actgtaaata aagcatcatc
     8341 atattctttt actactctcc atagcatttc aagcatttct tgagaatttg accatattgc
     8401 tgcaggagct actcctattt tgattcttcc attttctgta ttatggtgtt tttcaaacaa
     8461 tcttcttaca tctttttcaa ccgtttctac atcttgcatt attccaggat gaactccaaa
     8521 ttgagctcct gtattcatac atcctcttcc aagtattcct cttattccta attctttata
     8581 agcatctatt attccatcac aaagacctgg cttactatga ggatacatgt agtcaaccat
     8641 tgttgttata ccacttctaa gtccttcaat acatccaagc attgcagcat cataagtatc
     8701 tttgggctct aaatagttag ctgctggaaa tgtcatagtt tctaaccagt ctttaagtac
     8761 catatcatct cccaatcctt ttaataaagt ttggaataaa tgattatgtg tatttataaa
     8821 acctgggaat aaaactttac ctttagcatc tataattttt ttaacatcag tatatttact
     8881 ttctatctct ttagaatttc caatatcagc aatcttgtta tcttttacta ctaatgcccc
     8941 atcaaaaata acttctctct ctttattcac agttactatt atggcattct taataagtat
     9001 atccatcatt cttatttccc cccgcattat ttagtaattt ttcttttaat atattgacct
     9061 gttggatgtt ctttaacatt acaactttgt actacatgat ttcctctcaa aaatacatct
     9121 tcaactttac atttaacctt aaatccttca tatggagtat aatctacatt ttgtttttga
     9181 gttttataac taattgtttc ttctttattg atatttaaaa tgactatatc tgcatcactt
     9241 cctacagcta tctcaccttt tttaggatac attccaaata tttttgcagc attcgtagaa
     9301 gtaacttcca caaacttatt tacacttatt ctattttcta agaccccata tgtatataaa
     9361 agtgctaacc tatgttcaac accaggtgct ccatttggta tcttactgaa atcatcaatt
     9421 cccaagtctt tttgcccctt aaaattaaat gaacagtggt ctgtgccaac tgtttgaata
     9481 tctccactag acaatccttc ccaaaggtaa tttatgtctt ctttttttct taaaggagga
     9541 gacattacat acttagcacc ctcaaattta tccttattat ataaattgtc ttctaataat
     9601 agatactgtg ggcatgtttc tactatcata tctatatttt tttctctagc tatttttaca
     9661 gtttcaagtg actccctaca acttaagtgg actacatagg attttgaatt agataattta
     9721 gttatatcag caagtcttga aacagactct ttctcaacta tgttaggtct tgtaagtgga
     9781 tgatattttg gctccaaatt accattttgt atattttctt ctatcaatac atctagtaaa
     9841 tccccatttt cacaatgaaa tccaactata caacctaaat cccttgcttt ctttaaaacc
     9901 ctgtatattg ttccatcatc tactttcatg ccatcatatg ccatatacat cttaaaagat
     9961 actatcccat ctgaaataag tttttccata tgattaaatg tatctttatt taaacatgta
    10021 attgtcatat gaaaaccata atcacaataa caatttccac ttgctttttt atgatatgct
    10081 tctacacctt gcagtagatt ttccccctca ttggcttctg caaaatctag tattgtagta
    10141 gttcctccag ctatagctgc tcttgttcct gtttcaaaat tatctgcagt tgtaatagaa
    10201 cctgcattca tatcaaaatg agtatgtgtg tctattccac caggaattac aattttacct
    10261 gtagcatcaa taaccttatc accatttatt tctaagttat ttcctatttc aactatcttt
    10321 tcatcttcta tccttaaatc acttatataa gtcttatcag aggtaattat agttccacct
    10381 cttagtattg ttcccatata tacctcctaa cttttaagct ttaaagtatt ttctaagtat
    10441 tgtaaaactt tatttaaaat tgtattttct aaaggtgcta tattcagcac ctctagacta
    10501 tatttaaata atttattgtg aactaaatat tattttccgt atacagattt taatattcca
    10561 tagtaacctt ctgttcctat aaataactgt tcttgctcta tatactcatc tattgtgtga
    10621 gcaagatttt ccttagaagg accaaatcct atagttttta ttccagcttc acctgcatag
    10681 tgacttccat tcgtacagaa tgagtattga gttatttctg aatctattcc agcttctttt
    10741 aatcccttat acgctgcttg aacaaattca tcttcttcgt catataacca acctgggaag
    10801 aatctttcac tttctatagt atttcctgta tagcaatcag ctttttcaac cgcataagaa
    10861 acttttgcat ttaattctgg gtcttctttc atcatttcat ctaataaagc ttgtattgga
    10921 gctaatacgc cttctcttgt ttctccaact aataatcttc tatcaaaagt agctttgcaa
    10981 taatctggca ctactgatgc tcctggatat ggagaagatt ttatatctgt taaaactaat
    11041 attccatcac ctaaaactgg atgagttgga ggtactaatt gttgtatctt ttggattaca
    11101 ttagccattt tataaactgc atttacacct ttttctggat tagcagagtg agctggttta
    11161 ccaaaagttt ctactactat ttctcctcta cctctctgac caatctttaa gtttaactct
    11221 gaagactcac ctattacaac atagtcaggt tgaacagcct tacttatctc tctagccgaa
    11281 acaccttcaa atatttcttc atgaacaaca cctgctacat atagttctcc agcaaaatct
    11341 ctattagtgt ctttagcaaa atacgctaca gcagacatca ttgcagtata ttgacctttc
    11401 atgtcagaag ttcctctacc atatatcttt ccatcaacta tttttccttc aaaaggagga
    11461 acactccatt tacttgcatc tggaactgga actgtatcta tatgtccatc aaataatatt
    11521 ttcttacctg gcttgttacc ttttatacat cctactatat ttccatatct atctcttgac
    11581 caactatcaa aacctaattt ttcaaaagac tcttctattg cttttacaac accttcttca
    11641 tttccagaag aactaggatt ttgaattaat ttttggcata tttcagttac ttcttgtttt
    11701 ctttgttcgt ttaacatttc attatccccc tagatttttt ataatgtatg tattttatat
    11761 acttatatat tttctaaatt ttagaactta tatatcttct aaatatgtaa accaatatct
    11821 aataattgca ttttagtaat tccttatata cttggatatt ctccatccca aactatactt
    11881 ctatatttgt cagggtcagt atctccttct gtgcttatta aaagtattct tgaattttca
    11941 tctaatttta aatcttttct taaatctgct aaatcttctc tttccatagc tgctactaaa
    12001 agaccagttg taactgctcc agattctcca gaaattacct tttcatcacc atttaaagga
    12061 ttacctaatg ttctcatacc tttagcagaa acccagtctg gtgctgaaac aaatgctgct
    12121 gcatgatttt ttaatacttc aaatcctata gtatttggct ctccacaagc aagccctgcc
    12181 attatagttg gcatatctcc tccaacaaat cttggttttc catctccagc ttctgctgat
    12241 ttatagtaac aatcagcttc atcagcctct actactactg ttattgggca ttcatcatat
    12301 attgaagcaa catacccttg aactgcacca gcaagtgaac caactcctgc ttgaacaaat
    12361 acgtgtgttg gtctatctac tccatattct tttaattgct ctatagcttc ttgagccata
    12421 gttccatatc cttgcattat ccatgctggt atttcttcat atccgtccca tgctgtatct
    12481 tgaaccatta ctccatggtc atcagcttct gcataatcat tagctaatct tactgcatca
    12541 tcataattta agtctgttat actagcatct gcaccttctc ctttaatttt atttaatcta
    12601 aattcagaag aaccttttgg cattaataca acagattttt gacctaattt attagctgtc
    12661 caagcaactc ctctaccgtg atttccatct gtagctgtaa agaaagttat ttctcctaat
    12721 ttttctttta tttctttcga agtcaatttg tcatacccta actcagatat atctgtatct
    12781 aatctttgag ctaagtatct acccatagaa taagaaccac ctaatacttt aaatgcattt
    12841 aatccaaatc tataagattc atcttttaca tatactcctg caacacctaa tttttttgct
    12901 aaaccttcta ggtttgctaa tggagtttct ttatattgag gaaagctttt gtgaaaattt
    12961 ctaaccttag ttatttcttc ttcatttaaa aatttgatac aattttcctt atcgcccttt
    13021 ggcaaattat ttactttcca tttaatttct tttaacatct aaaatacctc caaattattg
    13081 ttaaattttt atactttaat atataagcaa ttaacatgcc aatactaaat atatactaga
    13141 tatttttcca tgactcttta gtatagaaat tgcaatgctt ttattatttt ttcttttcta
    13201 tctttagttc atacaatgta tgtagaattt aataactaaa aaaccttttc tatcttctca
    13261 ctttttaatt ctcattttta aaatttaaaa ataaatctca aaacactttg tttctatatt
    13321 ttttaatata aaatttataa aatctaaatt aaaacataaa atagtgatgc aataatctat
    13381 tacatcacta tttgtatata ttcaataata taataaatct ttagtggtct ctaagaggtg
    13441 atttttcatc ttttttaaca tctaattctt cttttacgac attccatttt tcaagaccaa
    13501 acttagaaac cataactgcc tctgctgcac cttttccaag tctttttact gtgtccatac
    13561 ctgtctcatc ctcttgggca ccttttgctt ttccatcttt actccatatt gtaccaccta
    13621 tatagcatcc acctaaacct ccagacacta acatttcatg cattaggaag aaatttatta
    13681 taggaagttt tgtcaattct tggccaccat atctagttcc accagtagtt atagctgcac
    13741 caaccttatt ttgaagtttt cctggatgaa ctaaatacat tggacgaagt ctattaaata
    13801 ctgctgtaag ttgagcagtt atattcatat cataaactgg agaacctact ataattccat
    13861 ctgcctccaa tattttttgc tctaattctt ggatatcatc ttttataata cacatagttt
    13921 cttttcttat acatgcatca caatgtacac aaggacttat ttttttccct ctaactgacc
    13981 aatactcagt ttctatacca ggtatagttt ctgcttcttt caaagcttct aacactgcat
    14041 attctgttgc tcctttacgt ggacttccac aaatacctaa tatctttgcc ataataatat
    14101 ctcctcacca aataaatcta tttttattat ctatttacaa atacaataaa ttgttatttc
    14161 tgctttaatt tctactattt taattttatt ggtaatgaat gtatctctac atcagttgca
    14221 ttatatactg catttgcaac agctggcgca actggtacaa cggcacattc tccaatactc
    14281 ttaccaccaa aaggcccagc tttttcataa ccatctacaa atgcaacttg acattttggc
    14341 atatctacag ttctaaataa tttatatgtt ttaaaatcag tagctttagg tctaccttgt
    14401 tcatcaaatg ccaattcttc actcaatgcg tatcctagac ccatatgaat cccaccttct
    14461 aattgtcctt ctaaatttag aggatttata actctaccaa catcatgtac agctacaaaa
    14521 tcaactactt ttatatcctt agtttcttta tctactaaaa cttcagcaaa atgtacacca
    14581 taagaagtac gtccagctgg tgaagaataa tcttcaacaa cagttaactc tcttaatgat
    14641 ttactttgac tatatactgc gacatcagaa agtgatgctt ttacattttc atcaagttta
    14701 ctaattacac atccattgtc tagatataaa tcttcttttg atgtttcaag taatttttct
    14761 gcttcttcta atataagatt tttcaatttc tctgctgtct ttttagctcc tccaccttct
    14821 acaaataccc ctctacttgc atagtcacca aggttgaatg tacatgcatc cgtatcagtt
    14881 tcaaatgtat caactttatc aggtgttatt cctaaaactt cagctaccat cattgtttgc
    14941 atagttacaa caccattacc catatcatga gctcctgtta gtagtgtcaa cgtaccatct
    15001 tcatttaatt taagagtcaa tgtaacaaca tctctatgtg caccaaaaac tccattacca
    15061 tgtgcaccta ttgccatacc tatacctctt aaatattttc cttcttcttt tggaagtttt
    15121 ttcttttcat cccacttaaa catcttctta ccttgctcta tacaatccaa tactctagga
    15181 tttccaagag aaccgtggaa gattatatcg acatcatctg gctctactgc atttttattt
    15241 tgaaaatcga ctaaatccat acctatttcc tttgctattt tcgcaaattg agcttgttga
    15301 gccataaata tttgaggtga cccatagcct ctcatagctc ctgctattgg tgtatttgta
    15361 tatacaggca tcccagtaaa ctttatattt ggtattttat aaactttaaa tactttatga
    15421 ctaagtgctc ctataacatt taaagcactt gatgcatatg ctcctgtatt tgtatatatt
    15481 tttatgtctt gtgctattac ttcaccatct ttatttacac cagtttttaa ttttacaaaa
    15541 gacccatgac gagttcttgt tgatatcata gattcctttc ttgtaagaac cattttaact
    15601 ggtcttcttg tcatttttga taatgcggct gctactggtt caattgtaag ttctaatttt
    15661 ccaccaaatg agcctccaat agcaggtctt ataactctta ctttatttaa tgacatccca
    15721 aaaatttgag atagtattat tctaaatcca aatgtatttt ggcaaggtgt atgtacagtt
    15781 aatttatcat tataatcata gtgtgcaatt acactatgag tctctattgc actatgatgt
    15841 attgctggag tagagtattc atcttcaaat atataatcac attccttgaa gcctttttct
    15901 acatctcccc catttatgtt gttttgagaa actatatttg aatctccatg tatgcagata
    15961 gcatcttctt ttattgcatc ttgtatagta aatacagctg gcaattcttc atattcaact
    16021 tttataagtt ttacagcttt ctctgctatt tctggagtct ctgcagctac tgctgcaaca
    16081 cggtcaccaa caaatctaac tgtatctgaa aatataactt cattttcagg tattttgtgc
    16141 tcataaaatc ttaatgaacc attgtatttt ctttgtgatg tattgagata agtagctata
    16201 gctctaacac ctactacttt ctcagcttca cttgtatcta tactttttat ttttgcatgt
    16261 gctacagggc ttaaaagcat cttagcgtaa agtacatttt gtggtttcat atcagccacg
    16321 tatttcattt gaccagtaac ttttaaagct gcatctttta gagggtatga ttttcctatt
    16381 accttttcca taattatcta ccccctaatc tagctgcaga taattttaca gcttctataa
    16441 tctttacata tcctgtgcat ctacagagat tttctttaaa agcttctcta atttcatctt
    16501 cattaggaga tgcatttcta tttaaaagag cttgtgttgt tataatcata ccaggagtac
    16561 aatatccaca ttgtacagct ccgacttcta taaaagcttc ttgtattgga tgaagatttt
    16621 ctccattagc aaaactttct atagtgtata taactttacc ttcgcagttt tttgcaagaa
    16681 gtttacaaga tttcatgtca actccatcta tcaaaacttt acatgctcca caactgccac
    16741 tattacaacc ttgtttcgct ccagttagat ttaatttttc acgaagtaca tgcaaaagag
    16801 tttcattctt ttcaacttct atttcataca tgtaatcatt aatatttaat tttatttttt
    16861 ccattttctc ctcctacaga taaactaatg ttgtaataga atattattac aatcttattt
    16921 taatattagt ataagctatt ccacttatgt ccttccattc tattagttac attagctctc
    16981 ttacataatt cttctgctgc atgttgtgca ttaagcaaca cttgttcttc actttcaatt
    17041 gtagttactt ttccattttc aagtattaca tttccatcaa ctaaaacact ctctacattg
    17101 tgcatactag ctgagtatac caaagttgat acaggattgt gaagaggtat tgattttgga
    17161 gaaagcattg agttaaatat tactaggtca gcttttttcc caatctccaa agaacctatt
    17221 tcatcttcca ttctaagagt tcttgctccc tcaattgtag ccatttcaag aactttctct
    17281 gcagaaattg ccagagggtc acaattattt actttgtgtt gtaaagctgt taatttcata
    17341 agctctacca tatcttgtgc gttattactt gctgcaccgt caagacctaa actcacattt
    17401 ataccttttt ttaacatttc tggcacaggt gcaacaccag aagcaagata catgttactt
    17461 gctacattat gagaaacttt tatgtcatac tttttaagca tttccatgtc ttcatcagtt
    17521 atacatacac aatgtactgc tacaacttct ggacctacta taccccattt ttcaagtaat
    17581 tttatatcta tttctccatg tatatccttt gttgctgttc ttgcaaattc tgtttcagat
    17641 atatgaactg taaaatatga atcatattct ttaactatat tccaaagcat cttacccatt
    17701 tcttcagata tagcccacat tgaagaagga gctacacaga tttttattct tccattttct
    17761 gaattatgat atttttcgaa tacccttctc aaatcttttt caaccgtttc cacatcttct
    17821 ataagctctt tgtgaatacc taaatctata caacctctac ctacaacccc tcttatacct
    17881 aaatctttat atgcctttac tattccatct gtaagtcctg gtctattgtg agtatgcata
    17941 taatcaacca ttgtagttat accacttttt aaaccttcca tacatccaag cattgcagca
    18001 tcataagtat cttgttctgt taagaatttt gctgatggaa acatcattgt atttaaccac
    18061 tcatgaagtg ccatatcatc acctaaacct tttaataaca cttggaacag gtgattatga
    18121 gtatttataa agccagggaa tattactttt ccattagcat ctataacttt tttagcatca
    18181 agatacttag gctcaatatc aactgtattt cctatgtcca agattctgtc accttgaata
    18241 gctattgctc catcaaatat aacatctctg tctttattaa ctgtaacaat tattgcattt
    18301 tttattagta tatcaatcat cttaaatccc cctttgaata ctttcattac aacattttac
    18361 catatggttt tctcatatta tatctaatac atttatccaa tattttcctc aagatttgaa
    18421 gtaacgtttt cagcactttt acgtgacttt aatttaaata atgtttgaag taatatagct
    18481 attattgctc cagaaactat acttgaccct ccaaggacag ttccaattgt ttctgggaat
    18541 tggtctaaaa cttgtggagc agttgtaaga cccatacttg ttgctataga tacacctgct
    18601 ataagattgt tttcttcagt gaatccatcc atactcataa tagagaaacc agacattgct
    18661 attgatgaga aaactactaa agttgctcca ccaacaacac aagatggtat agttgtcatt
    18721 attgcaccca atgctggaga tatccctgct agtaataata caagtgcccc tagtgctatt
    18781 acaaatctac ttgtaacttt gttcatagat acaattactg tattttggct aaatactcca
    18841 gttggaagag ctgcaaatag tgatgaaatt atagaagtta tagaatttcc taaaacaact
    18901 gatgctaatt cttcgtcagt tacctctcta tccattgctc ctactgtagc tattgtacag
    18961 gcacccatca tatcagctat acctattatg taaataatag taaacattac tattaactct
    19021 ggtctaaatt ctaatccaaa agctgctggt gttggtaaag atactatagc tgctccttga
    19081 acggctgaga aatcaaccaa tcctaaaact aaagatatag cataacctac taatattcct
    19141 attaatattg aagaattttt tactaaacct ttaccgtatt tatttatcat tattattaca
    19201 aaagcaacta taactcctac tgtgaagttt attgggcttc caaatgtttg tgtgccttct
    19261 cctccagcta aattctttat agctgttgcg aatagtccaa gtcccataca tgctattata
    19321 gttccagaaa ctattggagt gaatatatgt ctaattttct taactccaaa tcctacaaag
    19381 aatacgatta ccccagcagc aatctgtgct ccaaatagag ctgctaaacc atctttagct
    19441 gctactgaaa gacaagctcc taaaaataca taactcattc ccatcattac aggtaatctt
    19501 gaacctaact taaatccttt aaataaaggt attggatata actgtaaaaa cgttgctaaa
    19561 cctgctgcta acatagaacc ctgaatcaac attgttgctt gcccctggtt aagtcctacc
    19621 acgtttgcta ttaatatcgc aggtaccata tttcctacta tcattgctaa cagatgttgt
    19681 aaggccaaag gtattgattc ctttagtggt ggtatcccat cgacatcata ttttgaagta
    19741 ttacgtgttt tcataaaata aatcctccca tacataaata tcttgactaa atatttttat
    19801 aattattttc tataaatatt tttatgacca tgaatttatt gctcaaccga taaacacagc
    19861 taaactgagc tatttttata aaaaattaac aaatttctaa atattccctc cccgattttc
    19921 aacttaaatg aacattaatt gcctggtata tatttatttg ttaaattttt tattaaaatg
    19981 aatagctatc aaaaataatc taacaatctc atactaaata atttaaacaa ttcttttaaa
    20041 ttattatatc ttaattagtc tcttccataa cagctctttc tttagcctca tcctctagac
    20101 ttttatttgg tattattaga tttaaaacga atgcaaccaa tgttgcaatt actattggag
    20161 attctccaaa tactaacttt acaaatgaag gaaatgcctc ttgggctgct ggtactgatg
    20221 ttattcccat gcctaaggca attgccaaac caacaatggt aatatttctt gatgacaact
    20281 cttctgtaat aattaacttt atacctgtca ttgttatcat actaaatata gatattgtag
    20341 ctcctcctaa aacagaatat ggtatagtag tcattagtgc accaaattta ggcacaaacc
    20401 ccgacaataa cataaatata ccagctattc caagcacaaa tctacttatt actttgttca
    20461 tagctaccat ccccacgttt tggctatatg atgatggtgg taaacctcca aacaaagctc
    20521 ctatcatagt acaaattcca cttcctatta ctccacttga taattcctta tctgtgatat
    20581 tcctatccat gcctcccatt gtagtagctg ataaatctcc aattgcttga acagcattga
    20641 ttatacttac aattactact gagattatta caggcatatc aaattccatc ccaaattcaa
    20701 gcggtttagg tatcgcaaac caagttgcct ctctaatagg gtcaaaattt attataccca
    20761 gaactaaaga tacacaatat ccaactataa ttcccaaaaa tattgctgcc aattttgcat
    20821 atccttttgc aaattgacta agacctataa ctaccactaa tgttatagcc gctactgccc
    20881 agttttgcat agaggcataa gtaggactat ttacaccacc tgccatataa tttattgcta
    20941 taggatacaa agataatcca attgtaaaaa ccactgttcc tgcaactata ttcggaaaaa
    21001 attttcttat cttttttatg aatatcccta ttaatactgt agccactccc cctattaatt
    21061 gtgcacccaa aatgcttgct aatccataat ttcctccgac tgctacaagt gttggtacat
    21121 aagtaaaacc aactccaaaa attataggca atcttgaacc aatatttcct attggatata
    21181 gttgtataag tgttgatata ccagctatta ttaatgcata ttgcactaaa agtgttattt
    21241 gtgtagggct aacacccaca gctcctccta cgactatagg tactgtaaca gttccaacta
    21301 tcattgctag tatatgttgc attgatagtg gcaaacactt taaaattggt ggccttccat
    21361 caatatcaaa catagaaaca ttcttttgat atttactcaa ggttatcact cccaactatt
    21421 ttttaatgac agttattatt atctcacaca acatcctttc tttttttatt ttgtcatctc
    21481 aacttaatat gaagcaatta taatgccaat tttttaacat aattgtttta catatataat
    21541 ttttattata tttgttagta tttgataatt tattaaagca tttatttttt taaattcttt
    21601 taaatttttt ttatttttgg ataataaaat gctattacac aaaaaaacac ttagaaaata
    21661 gttttccaag tgttttttat caattttata atttcaaatt ttagaattga gaataaaaag
    21721 cctaattatt atacatctat ttttctgtac aatgtagcta gtgatattcc aagttttttg
    21781 gcagctagtt ttttagactt agtatcattt ccgtaaaact ttaacacttt ctttatatag
    21841 gctctttcaa actcttcaag tgtaagtatg tcttgttcca tacttatctc atagtcactt
    21901 tcctcaagta actttatatt tatattattt aacttaaaat attcaagtat ctttctattt
    21961 attattcctt tatgtattat tccatcttcc tcaagaaggt ttaatgccag ttctatagta
    22021 ttttccaact ctctaatatt tcctggccaa ggatacttaa gcaacatttg ttccacatct
    22081 ggctctatat ggtacacgtt tttcttcatc tttctcgaat atttgtctat aaaattgttt
    22141 attaatattt gtatatcgtc tcctctttct ctaagtggag gcacttctaa aggtattaca
    22201 ttcaatctat agtataagtc ttctctaaat ttattttcct taaccaactc aaataaatct
    22261 ctattagtag ctgatatgat tctaacatct atatcaatta gttcatttga acctattctc
    22321 gtaaacttct tttcctgtaa taccctcaat aactttgatt gtagttgaat tggcatatct
    22381 cctatctcat ctaaaaatac aacccctcca ttggccaatt caaacttacc aattttacct
    22441 tttgaatctg ctccactaaa agctcctttt gtatatccaa aaagttcact ttctagtaaa
    22501 ggttctggta tagcagcaca gtttatagca acgaatgttt tattccctct gtttcctgcg
    22561 agatgaatgg ctcttgctat taattctttt ccagtgccac tttctccagt tatagctaca
    22621 gtagaatcac tatttccaat tttacaaatt ctattcttaa gagcacgcat tacatcagac
    22681 tctccaatta tggagtctac tgttgttgtt ccccaaatat tatatacttc cattccacca
    22741 tacattactg aatcactgtg tttgtccata aaatatcaac tccaaataag tattctatat
    22801 aataatcatt cacattatct atttaattat atcataacag aaaagcttag ttataattta
    22861 ataatattat tttaaaacaa aacttaataa aaagtatatc tacttagttt taatttgata
    22921 gatatacttt cttcatttta caaaaatcct ctattaaata agcaattaca atgccatatt
    22981 ttatatggaa ataattttta aaatttttaa ttta
//
LOCUS       DAEHWO010000062        22810 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEHWO010000062 DAEHWO010000000
VERSION     DAEHWO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22810
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.062"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            30..431
                     /locus_tag="KNP54_002788"
     CDS             30..431
                     /locus_tag="KNP54_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBF0893661.1"
                     /translation="MILKKHLETILYLFFGALTVLINIITYLFFTRIINFTFLLSNSL
                     SWSIAVLFSYITNKFFVFKSEKTEFLFLLKEFVSFLSCRLFSGFIEILLMYLMIDLFS
                     LNDILVKIGTNIIVIILNFVFSKVVVFKHRN"
     gene            complement(496..2613)
                     /locus_tag="KNP54_002789"
     CDS             complement(496..2613)
                     /locus_tag="KNP54_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBF0893662.1"
                     /translation="MQISKKIISLLTAAFLSIVLPSNVVNASNKDSLIGSGRWETAIK
                     ISQNGWLRSDNAVLVNDNSIADALSATPFAKLKDAPILLSGSKELDFRTKSELKRLGV
                     KNVFLVGGSNALGVNVENELKSEKITVERIFGNDRYETSLKLAEKLNNEKDISDIIVV
                     NGEKGLADAVSVGSIAAQNYMPIILSDSNLGVEVANKFIKAQNIKNSYIIGGLNSISN
                     EIEKNLPNSKRISGNNRNETNANVIKEFYKETDLRNAYITKDGMKKQSDLIDSLSVGV
                     LAAKNNSPVVLVGNKIDSIQKDVLNTKIFSTVTQVGGIGNENVYKDILDMQEETKYTV
                     ETIEELDSALKKVDANDIIKFRPDKKISESFKLETEKAIKVDLYGEYSQSITINMPNG
                     ELNNTGDISKTLILKDIKDGTLTNSGYINQMDISDDNGCKIENENNGQIWIVTIFSSA
                     KDVNIRNDGTITKIDNDSSSTNIRNSGKIDTVSGNKEPGISGNKPNTNNTDKDDDSDT
                     AAGLSPKISACSPLENNQIMLTVPQKPKNSNYKIYYRVLSYKPSAMRVGDRININDWD
                     LVEDTEPLKVNAKNGSYIEVVEIDYTRKKVSRWGRAGATDDGFKIVANGIKSTVSVDE
                     NSKVTISVTGYNGNKVYYRIKTTKPEAMNVGDEIDSSWKSTSNSDIILEGNKVNGLYV
                     ELASGENNKVEKWGATDKIEIVS"
     gene            complement(2644..3351)
                     /locus_tag="KNP54_002790"
     CDS             complement(2644..3351)
                     /locus_tag="KNP54_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBF0893663.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAKEIILKYLEEYPEAKVKTVTPFKASGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDDLELNKTQYVHAP"
     gene            complement(3458..5329)
                     /locus_tag="KNP54_002791"
     CDS             complement(3458..5329)
                     /locus_tag="KNP54_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HBF0893664.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRGLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            complement(5673..8018)
                     /gene="secA"
                     /locus_tag="KNP54_002792"
     CDS             complement(5673..8018)
                     /gene="secA"
                     /locus_tag="KNP54_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBF0893665.1"
                     /translation="MSVLDTILDKADEQEIRRLNVIVDKIESLEKDIENMSDDELKKM
                     TDLFRDRLKKGETLDSLLPEAFAVAREASKRVLGMRQYRVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVVTVNDYLAQRDKELMQPVYEFLGMSVGVIIADLI
                     PEVRKVQYNCDITYGTNNEFGFDYLKDNMVTKKFDKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGEGDEDSKLYELANSFIKTIKEEDYELDRKDKTVALKESGIDKAESFFGIKN
                     LTDIENIELYHHINQALRGHKLMEKDVDYVVVNQEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKDESKTMATITFQNFFRLYNKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNKPIIRADLHDKVFRTEKEKYQAVVEEVIRIHKTKQPILIGTVSVEKSEMLSGMLKK
                     EGIKHQVLNAKENDKEALIVSKAGKLGSVTIATNMAGRGTDIALGAGDKEEESRVKEL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKSIEKLMKR
                     PNSNKNNSIESKSLTKAIERAQKGVEGKNFELRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIQVDIQNMVKDIIKEAAAEYLTKRKRDYYGYFKHLYNTFMPADTLLIPDLDNKS
                     IEDIIDSTYEISKRVYDLKKMVVGLDKITEMEKIVLLKVVDQYWVEHIDAMEQLKQYV
                     GFKSYAQKDPFKEYAMEGYEMFESLNKNIRETTIQYLYKFN"
     gene            complement(8254..10434)
                     /gene="slpA"
                     /locus_tag="KNP54_002793"
     CDS             complement(8254..10434)
                     /gene="slpA"
                     /locus_tag="KNP54_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBF0893666.1"
                     /translation="MNKKNLAVVMSAVTVIGSAAPVFAAAEDSFPNGNTTVSSSKYSD
                     IERILKKYVADGVTGITVNFFDKKGNPKGVSISSLEASQISYVKDEIKDLKAGEYAKI
                     SVKITDGTEKKYDDTLLKELDSNAVVTKVGTATTVKIVDQDGNSIENDAKLKLQKYDT
                     TTSAYVDGATKDEVLAATKAAVKTSKFTDKTGNNATGTVAITATYADAVAGAIKLKYD
                     TQAAVAPTLDTAVASLDGTKEIYDFSKPVITVNTTDGTSKLSFEKTGEKVGAVESNVT
                     VIAASDETVTISGDAKEKAEALAKKYVFKDTELEDAYKTVTASDFEKTDNDYYEVVLY
                     PTGKRLNTASTYASSNYKPELPTSDRVDTPAIITLRSTNKNNLKSALDELRTYNNSYS
                     NNSVLAGDDRIETAIEISKDSYNADGGIKGDYVEANEVVLVGSQSIVDGLVASPLAAV
                     KDAPLLLTSKDKLDSSVKSEIKRVMGLDDKTGITSKKTVYIAGGENSVSKEVANELKD
                     MGLKVERLSGDDRYATSLEIADEIGLNHNKVFVVGGTGLADAMSIASVASNKEMPIVV
                     VDGKGKDLSTDAKDFIGSAYVDIIGGKSSVSEDMEDAIDDATGKSPERVSGDDRQDTN
                     AEVIKTYFEKDNSDSVISTGVKNFYVAKDGSTKEDQLVDALAIAAVAGHNEAPIVLAT
                     DSLSSDQSVAISKVTNSDDSKKLTQVGKGIADSVIKRIKDLLEL"
     gene            complement(10727..12325)
                     /locus_tag="KNP54_002794"
     CDS             complement(10727..12325)
                     /locus_tag="KNP54_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBF0893667.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVADQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNNLKPNIEGTVDTSKAGTYVLNVSAFDNFGQKCEINVNVKVIINTSTKDPNS
                     YEFKAMVSNEMYNLVNSYRKEKGKKSLRELDSLAGMANAWSKYMDEKKIFAHEIDGKN
                     AAEVFSGFGMRTDENIAYLPMNVKSVYTSKDAKEIAKSVFDLWKKSSKYNDNMLKEEF
                     YSFGFGMYVSNQREVNATMEFLNS"
     gene            complement(12544..14145)
                     /locus_tag="KNP54_002795"
     CDS             complement(12544..14145)
                     /locus_tag="KNP54_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBF0893668.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCISASKSNGQPPAITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSKLEGMANAWSKYMMDNKVFEHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKSVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            complement(14512..16392)
                     /locus_tag="KNP54_002796"
     CDS             complement(14512..16392)
                     /locus_tag="KNP54_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBF0893669.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKVTINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGSGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGDDRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNDKLPQKTVEELK
                     RLNPSKVVVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(16602..22565)
                     /locus_tag="KNP54_002797"
     CDS             complement(16602..22565)
                     /locus_tag="KNP54_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBF0893670.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSDSESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDEQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSKSTLE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELARYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRIEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDANTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(22689..22774)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT         6527 a         4287 c         2458 g         9538 t
ORIGIN      
        1 atatatacca aataatggag gaaaattttt tgatattaaa aaaacatcta gaaacaatat
       61 tatatctttt ttttggtgct ttaacagttt taataaacat tattacttac ctatttttta
      121 caagaattat taattttact tttttattat caaactctct atcttggtct atagcagttt
      181 tattttcata tataacaaac aaattttttg tattcaaaag tgaaaaaact gagtttttat
      241 ttctattaaa agaatttgta tcttttttat cttgtcgttt attttctggt tttatagaaa
      301 tattacttat gtatttaatg attgatttat tttctttaaa tgatatctta gtaaaaatag
      361 gcactaatat aattgtgata attttaaact tcgtcttcag caaggtagta gtttttaagc
      421 atagaaatta acattattat atttatcttt atgcagaata aggagttgcc taaaaaaaac
      481 aactccttat tagctttaag aaacaatttc tattttatct gttgctcccc atttttcaac
      541 tttattattt tctcctgatg ctaattctac ataaagtcca tttaccttat ttccttctaa
      601 aattatatca ctattagaag tacttttcca actggagtct atttcatctc ctacattcat
      661 agcttctggt tttgtagtct ttattctata gtaaacttta ttaccattgt atccagttac
      721 actaatagtt actttagaat tttcatcaac agaaacagtt gattttattc catttgctac
      781 tattttaaaa ccatcatctg tcgcaccagc tcttccccat cttgaaactt tctttcttgt
      841 ataatcaatt tcaacaactt ctatatatga tccattctta gcatttactt ttaatggttc
      901 cgtatcttca accaagtccc aatcatttat gttaattcta tcaccaaccc tcatagctga
      961 tggtttatat gacaaaactc tataataaat tttataattt gaatttttag gtttctgagg
     1021 tacagttaac ataatttgat tattctcaag aggagaacat gcacttatct ttggagataa
     1081 tcctgctgct gtatcactat catcatcttt atctgtatta ttagtgttag gtttattgcc
     1141 acttattcct ggttctttat ttccactaac agtatcaatc tttcccgaat ttcttatatt
     1201 agtacttgaa gaatcattat ctatctttgt tatagttcca tcatttctta tatttacatc
     1261 ttttgcagaa ctaaatattg ttacaatcca tatttgtcca ttattttcat tttcaatctt
     1321 gcaaccatta tcatcagaaa tgtccatttg atttatatat cctgaattag ttaaagttcc
     1381 atcttttata tctttaagta tcaatgtttt acttatatca cctgtattat tcaactctcc
     1441 atttggcata tttatagtta ttgactgact atattctcca tataaatcaa cctttatagc
     1501 tttttcagtc tctaatttaa aagattcact tattttttta tcaggtctaa actttataat
     1561 atcattagca tccactttct ttaaagcaga atccaattct tcaattgttt caactgtata
     1621 tttagtttct tcttgcatat ccaatatatc tttatagaca ttttcatttc ctattccacc
     1681 aacctgagta actgtactaa atatcttagt atttagtaca tctttctgaa tagaatcaat
     1741 tttatttcct actaatacca ctggagaatt gttttttgca gccaacactc caactgatag
     1801 tgaatctatt aaatcacttt gttttttcat tccatccttg gttatatatg catttcttaa
     1861 atctgtttct ttataaaatt cttttataac attagcattt gtttcatttc tattatttcc
     1921 tgatatcctc ttagaatttg gtaaattttt ttctatttca ttagaaatgg aatttaatcc
     1981 tccaataata taagaatttt ttatattttg ggcttttata aatttattag ctacttcaac
     2041 tccaaggttt gaatctgaaa gtataattgg catgtaattt tgagctgcta ttgaaccaac
     2101 acttacagca tctgctaatc ccttttctcc atttactaca attatatcag aaatatcttt
     2161 ttcattattc aatttttcag ccaattttaa ggatgtttca tatctatcat tcccaaaaat
     2221 tctttcaact gttattttct ctgattttaa ttcattttct acatttacac ctagtgcatt
     2281 tgaacctcct actaaaaata cattttttac tccaagcctt tttagttctg attttgtcct
     2341 aaaatccaat tctttacttc cagatagtaa aataggtgca tctttcaatt tagcaaatgg
     2401 agttgcagat aatgcatctg ctattgagtt atcattcact aatacagcat tatcagatct
     2461 taaccaaccg ttttggctta tttttattgc tgtttcccat ctacctgaac ctattaaact
     2521 gtctttatta gatgcattta ccacattact aggtaaaaca attgataaaa atgctgctgt
     2581 taataaagat attatttttt ttgatatttg cattaattat ctcctcctaa tttaaatata
     2641 attttatgga gcatgtacat actgtgtttt atttaattct aaatcatcaa aatgagattt
     2701 tactgaatgg tatcctatag cataatgtcc actttcagga ttccatttct tatatgcatt
     2761 catcgcactt aataacttct cctcttgact aggtaatacc ttccagactt ctacatttgg
     2821 attaactttt ttaaaatcct tatagtcata tggttctaca taaaatctta aatcttttat
     2881 ttttccttct ctatataact ctagtgcagc ttctcctaat gctctatgat cttcatgtat
     2941 tccactagct ttaaacggag taacagtttt tacttttgct tctggatatt cttctaagta
     3001 tttaagtatt atttcctttg ccttttcttt gcttaactca ccatcatgag ctctattatc
     3061 ttctatatgt atattacttt cttttacacc cattgcttca cagctatcct taaattcttc
     3121 atctctatct tttgaaaatt cactttctga taaagagtat ttatgaacat ctttaatatg
     3181 ataagaacat gaccctccat catccaaaac ttttcttatt atagatttac taccatctgt
     3241 gcacaatatg acatgtgtat cacttttttc aacatgttca attatagcac ttcccatact
     3301 taaggtttca tcatcttgat gtggtgtaaa aaacaaagtt gcatctacca ctactacatc
     3361 ctcctacttt ataaaatgtt ataatttaca ataaatagca taattataga aaaagattcc
     3421 tgtattaatt aaggaatctt ctccacagta taagttatta ccaacctagt attttagcta
     3481 tcttttgtat tactgtcaat tcaactccat tacctatttg agttacttct gcaccaagat
     3541 ttaatttttt actaagtgca ttcttttgtg agtctgttat atcagtttta gctagaagta
     3601 ttggaccttt acctgctgct agaggtcctg ctgccaatgc atctactagc ataccattat
     3661 ttccatatcc atcttttgct atatatagtt tatctaattt gccataatat gtttctataa
     3721 ctttagcatt agtatcgtgt cttgtttctc cttcaactct ttgaactttt ctatctttat
     3781 caatatctgc aagttgattt tcaatttggc tagatacatt attagagcca ccaactatgc
     3841 caatctcttt tccatccatc aatttgatag catctgctga tagatcattc caaccattta
     3901 ctattatagg agccttaagt tcagcagctt tagcagctat actcatagca tcagcctccc
     3961 cttttgcgcc tactacaaat gcatctttaa aagaccccat agcttttgct actgctacag
     4021 aagtcatatg tctatcatct ccagctagtc tttcaacatt cttagttact gattctaatt
     4081 gctttttagc tgtatttgat actgctgatt ctccacctac tatatatatt ttagctgatg
     4141 ggcttttctt aattatatct tttatataat ctaaagttac ttttggtatt tcattatcag
     4201 atgctaataa tataggtgct tttttagatt gagcaagtgg tgtagctgct aatccgtcaa
     4261 ctagtttatt tgaattaact ataactatat tgtcagtata ttttgtttgt tttgctatag
     4321 ccactgcagt tgcatatcta tcatctccag ctatcaattt aacctttgaa ttaccttcta
     4381 atgcagcttt ggcatctttt aaatcttttt cattggtact ttctacagta agctctgttg
     4441 cttttccaga tgcatcagta tacttaatag taaatttata ttttcctgtt tctgaatctt
     4501 ttgctgaaat atcactaatt gactttgatg taccatttgc taccatatta cctttaacag
     4561 tcaatctata tccatcatat aaatcttgtg gtgaaactgt atttaggtca ctatttttta
     4621 tagttatttc ggccaattgg acatcatcaa tatttttagc tcctgctaca cctagtttat
     4681 cgattttatt tactctaaat ccttctgcag aagggtctaa atttgttcca gttgaatcaa
     4741 ctggatttgc tgttaaatca actttttcat caccaatacc tacatatata gttttagaag
     4801 ttactgtttc tgttttatct cttaaagtta taactaactt atctttagca ctatcatatg
     4861 aagcttttac atctgcaact ttataaattc cattggtttc agttttagct ttttctgtta
     4921 tagaattagc ctcagcggaa aggtctgctg aattttcata tttttcagtt gcttctgcaa
     4981 ctacttcatt tgcactattt gttatatgtc ctttatctgt tatagttaca ataagttctt
     5041 tattttctcc caaagcattt actaatttct ctaattcatc tatattagtt attattttta
     5101 attttgataa agtctcacca acttttattt catatattgg ttgtccaact tgagaacctc
     5161 ctgtatactt ttgagacatt aaacctctaa ctttcgaaac taattctgta gcctctttct
     5221 tagttattgt ttcttttttt acctgtgtag tttctgcagc aaaaactgga gctactgatg
     5281 tacttatcat tgcagcagcc ataattacag aaagattttt tttattcatg gtattttccc
     5341 cctaaaaaat tcaaattttt attatttttt ccttatttac caattataat atatatttga
     5401 tattatttca ataaatgaga cttattgtaa taattaacca aaagatataa actttttctt
     5461 atattttatt tttttaatat ttacgtatac aaaaaagtaa caaaattgta atttttttta
     5521 ataatccagt ttataactaa tagacttttc atcttcttta tagtataata ttaaatggaa
     5581 gaaagaaatt tcaagcatct cttttttccg tatttctcac atagaaaaag aggctgatta
     5641 tcagcctctt tttcctatac agtttaaatt tcttaattaa atttatataa atactgtata
     5701 gtcgtctctc ttatattttt atttaatgat tcaaacatct cataaccttc catagcatat
     5761 tctttgaaag gatctttttg agcatatgat ttaaatccta catattgttt taattgctcc
     5821 atagcatcta tatgttctac ccaatattga tcaactactt ttaaaagaac aattttttcc
     5881 atttcggtta ttttgtcaag gcctactacc atctttttta aatcataaac tctttttgat
     5941 atttcataag tactatcaat tatatcctca atacttttat tatctaagtc aggtattagt
     6001 aaggtatcag ctggcataaa tgtattataa agatgcttaa aatatccata gtaatccctc
     6061 tttctttttg ttaaatattc agcagcagct tcttttatta tatctttaac catgttttga
     6121 atatctactt gtatatcttc atcatttaga actttatttc tttcgttata gattactttt
     6181 ctttgttcat ttatagtatc atcatattta agaacatttt tccttaattc aaaattttta
     6241 ccttccaccc ctttttgagc tctctctatt gcctttgtaa gagatttact ttcaatagaa
     6301 ttatttttat ttgaatttgg tcgtttcatt agtttctcta tactttttcc accatacaat
     6361 ttgattacat catcttcaag actaacaaaa aaccttgatg ttcctggatc accttgacgt
     6421 ccagaacgcc ctctaagctg attatcgatt cttctagatt catgtctctc agttcctatt
     6481 acataaagtc ctcctaattc ctttactcta ctttcttctt ctttatcacc tgctcctaaa
     6541 gcaatatctg ttcctctacc tgccatatta gttgcaatag ttactgaacc caacttacca
     6601 gcctttgaca ctatcaatgc ttctttatca ttttccttag catttagaac ttgatgtttt
     6661 attccttctt tcttaagcat accagataac atttctgatt tctcaacaga aacagtacca
     6721 ataagaattg gctgttttgt tttatgtatc cttattactt cttctacaac agcttgatac
     6781 ttttctttct ctgttctaaa cactttatca tgaagatctg ctcttataat tggtttgtta
     6841 gtaggaattt gtacaacatt taatttataa attgattcaa attctccttc ttcagtttta
     6901 gcagtccctg tcataccaga aagtttatta tataatctaa agaaattctg gaatgtaatt
     6961 gtagccatag ttttagattc atcttttatt tctacccctt cttttgcttc tatagcttgg
     7021 tgtaagccat ctgtatatct tcttccatcc attactcttc ctgtaaattc atcaactatc
     7081 attacttctt gattaacaac aacataatca acatcttttt ccataagttt gtgaccccta
     7141 agagcctgat ttatatgatg atataattct atattttcta tatctgtaag atttttaatc
     7201 ccaaaaaatg attctgcctt atcaatacca ctttccttta gagctacggt cttatctttt
     7261 ctatctaatt cataatcttc ttcttttatt gtttttataa atgaatttgc taattcataa
     7321 agttttgaat cttcatcacc ctctccagca attataagtg gagttctagc ttcatctata
     7381 agaattgagt caacctcatc aactatggca aaattcaact ctctttgtac tttatcaaac
     7441 tttttagtta ccatattatc ttttaaataa tcaaatccaa attcattatt tgtaccataa
     7501 gtaatatcac aattgtattg aacttttcta acttcaggta taagatctgc aataattact
     7561 cctacagaca tacctaaaaa ctcatacact ggttgcatta gctctttatc acgttgtgct
     7621 agatagtcat ttactgtaac aacatgcaca cctttacctg ttaaagcatt tagataaaca
     7681 ggtgcaactt ctaccaaagt tttaccttca ccagttttca tttctgctat ttttccttga
     7741 tgaattacaa tgcctccaat taattgaacc ctatattgac gcattcctaa aactcttttt
     7801 gaagcttctc ttgccactgc aaatgcttct ggtaataaac tatctaaagt ttctcctttt
     7861 tttaatctat ctctaaatag gtctgtcatt ttttttaatt cgtcatcaga catattttct
     7921 atatcttttt ctaaagattc tattttatca actatcacat taagccttct tatttcctgc
     7981 tcatctgctt tatccaatat tgtatccaaa actgacatat ttaatttacc tcctttttta
     8041 tcatacaatt actattatac cttaaaatta tagaatagta gacaattatt tttatttata
     8101 gtataataat catacttaaa taaattacat ctttaattat ttaggtattt ctcacaaaaa
     8161 aaggaactat ttttagttcc ttttttaatt tctttttata aaaaagagaa cttcttcaaa
     8221 gaagttccct cttatttata gtttaatttt atcttataat tctaataaat cttttattct
     8281 cttaataact gaatctgcta ttcctttacc aacttgagtc aatttcttag aatcatcaga
     8341 atttgtaact ttacttattg ctactgattg gtcagaagat aaactatcag ttgctaaaac
     8401 tattggagct tcattgtgac ctgctactgc tgctattgct aacgcatcta ctaattgatc
     8461 ttcttttgta gaaccatctt tagcaacata gaagttttta acacctgtgc taattacact
     8521 gtcactatta tctttttcaa aataagtttt tataacttct gcattagtat cttgtctatc
     8581 atctccacta actctttctg gactcttacc tgtagcatca tctatagcat cttccatgtc
     8641 ttcagaaaca ctagattttc cacctattat atctacataa gcacttccta taaagtcttt
     8701 tgcatcagtt gataaatctt ttccttttcc atcaactact actattggca tttctttatt
     8761 agaagcaact gatgctatac tcattgcatc tgctaatcca gtaccaccaa ctacaaatac
     8821 tttattatgg tttaaaccta tttcatcagc aatttctaaa gatgtagcat atctatcatc
     8881 accagataat ctttcaactt ttaatcccat atcttttaat tcatttgcta cttctttaga
     8941 tacagaattt tccccaccag ctatataaac agtcttttta gatgttatac cagttttatc
     9001 atctaatccc attactctct ttatttcaga ttttactgat gaatctaact tatcttttga
     9061 agttaataat aatggagcat ctttaacagc agctaaaggt gaagctacta gaccatctac
     9121 tattgattgt gatcctacta atactacctc attagcttct acataatctc ctttaattcc
     9181 tccatctgca ttataagagt ctttacttat ttctattgca gtctctattc tatcatcacc
     9241 agctaataca gaattatttg aataagaatt attataagtt cttaattcat ctaaagctga
     9301 ttttaagtta ttcttattag tagatcttaa tgttattata gcaggagtat ctactctatc
     9361 acttgtaggt aattctggct tatagttaga tgatgcatat gttgaagctg tatttaatct
     9421 tttacctgtt ggataaagaa ctacctcata ataatcattg tcagtttttt caaaatcact
     9481 tgctgttact gtcttatatg catcttctaa ttcagtatct ttaaatacat attttttagc
     9541 taaagcttct gctttttctt ttgcatctcc agatattgta actgtttcat ctgatgctgc
     9601 tataactgtt acatttgatt caactgctcc aactttttct ccagtttttt caaaacttaa
     9661 ttttgatgta ccatcagtag tattaaccgt tataactggt ttactaaaat catatatctc
     9721 tttagtacca tcaagagatg ctactgctgt atctaaagta ggtgctactg ctgcttgtgt
     9781 atcatatttt aatttaattg caccagctac tgcatcagca tatgttgctg taatagctac
     9841 tgttcctgta gcattattac cagtcttatc agtaaatttt gaagttttga ctgctgcctt
     9901 tgtagctgct aaaacttcat ctttagtagc tccatctaca taagctgacg tagttgtatc
     9961 atatttttgt aactttaatt tagcatcatt ttctattgaa tttccatctt gatctacaat
    10021 cttaactgtt gttgcagtac caactttagt aactacagca ttactatcaa gttcctttaa
    10081 taatgtatca tcatattttt tttctgttcc atctgtaatt tttacagata tttttgcata
    10141 ttctccagct tttaaatctt taatttcatc tttaacataa cttatttgac ttgcttctaa
    10201 acttgatata gatacccctt ttggatttcc ttttttgtca aaaaagttaa ctgttatgcc
    10261 tgttacacca tctgcaacat attttttaag tattctttct atatcactat acttactact
    10321 agatacagtg gtatttccat ttggaaaact atcctctgct gcagcgaaaa ctggtgctgc
    10381 tgatccgatt actgtaacgg cagacattac aactgccaaa tttttcttat tcattcctta
    10441 aattcctccc aacattatat taattacatc tctttaatta tgtacattaa aattccatgt
    10501 tcatataaac caaatatttc tcacactctt atgatagact atataaaata gaatttcaat
    10561 aatttatgca aaattaatag aattttcttt caacattttt cccctttttt ttgctatttc
    10621 atatttttta aattaaattt tcaattttaa ttttattaat acatttattt atctgattta
    10681 atcaatatat attaatattt tctaccataa aatattaata tatactctaa ctatttaaaa
    10741 attccattgt agcattaact tctctttgat tagaaacata cattccaaag ccaaaactat
    10801 aaaactcttc ctttaacata ttatcattat acttagaaga cttcttccat aaatcaaata
    10861 cagacttagc aatctctttt gcatctttag atgtatatac agacttaaca ttcataggta
    10921 aatatgcaat attttcatca gttctcattc caaagccaga aaatacttca gctgcatttt
    10981 tcccatctat ttcatgagca aatatcttct tctcatccat atacttagac catgcatttg
    11041 ccattccagc taaagaatct aattctctta aacttttctt acctttttct tttctatatg
    11101 aattaactag attatacatt tcattagata ccatagcctt aaactcataa ctattagggt
    11161 cttttgtact tgtgtttata attactttga catttacatt aatctcacac ttttgcccaa
    11221 aattatcaaa agcacttaca tttaaaacat acgttcctgc cttactggta tccacagttc
    11281 cctcaatatt aggcttcaaa ttatttccat aataatcagt ggcaactata ttcaacatac
    11341 tattatcaaa cttatcccct acagaaatct ctacatcatt agcagtgatt gtaggcattg
    11401 tatttttatc agatgcagaa ctaatacatt ggtcagcaac cttcttatcc attccaccta
    11461 aagaagtaac ttcatcagca cctctaagca cactcttatc acttccatca ttaacaagta
    11521 ctataggttt gtccttagcc aacggagaac cagccacagc atcaactaac ttataccctt
    11581 gagaaacata aaacttcttt gttcctttat aaaagcgttg tataaccttc ttattagttt
    11641 caaatctatc tttaccagca atcctaacag aattagtctt actcacaagt tcattactca
    11701 ttatctcctc tgacccaaga gaataacatt gaacgccatc aaccttaaat ggtatactct
    11761 ttccatcagt aagtataaca ggaactccat ctctagcagc tacagaagat acactcattg
    11821 catcagcctc acctgtgtat ccatttacaa gaaaaacctt atcaccatca tttactggtt
    11881 taatagctga aatctcctta gctataagat agctagtctt tattctatct tccccaccaa
    11941 ttcttttaac ttcaatccct ttattcttaa gttgattttc tacagattta cctattgtat
    12001 cctctgtacc tataacataa gcattcttaa catcctttag tcttttttca acatctgttg
    12061 gtatcttatc tctttgcact aacattatag gagcttttac aactccagat aatccacttg
    12121 cacttaatcc atctactata gaattatcag tatttactaa tatgactgta tcatatattt
    12181 gtttatctgc tatcaatgca gaagtctcat atctatcttt cccttgtatc ttttctatac
    12241 tcgaaagtgc attgatattt ggtgctcctg ccattattaa tgatattgtc aatcctattg
    12301 ataatactct cttatttacc ttcatcgaac tcctcctact aattttttta tataattcag
    12361 ctaatcataa attacaccct cagtagtgat tccctcaaaa tttataaact actaaaacaa
    12421 aaaacaccta aaataccata acctgtaaag caataataaa acagattaca aaaagtactt
    12481 tagatgtgat tttcatttta taatatcagt aaattaacaa aaaaacaaga tttatggaat
    12541 tttttacaag ctaccttcat tgccatttaa aaactcttga gtagcatgca cttgaccatc
    12601 agataatata taaagcccaa atccagtact ataaaactca tcactaagca tgtttgcatt
    12661 gtattctgga gatttcttcc acacttcaaa tatagccttt gccaagtctt ttgcatcttg
    12721 agttgtttga acactcttag aatctatata aatatatgct atattttcct cacttctcat
    12781 tccaaactca gaaaatactt gtggagcatt tttgccatct atataatgtt caaaaacttt
    12841 gttatccatc atatacttag accatgcatt tgccatacct tctagcttac tagatactac
    12901 caaaggctct ttaccttttt cttttctata ggaattgatt aagttataca tttcagtaga
    12961 taccattttt ttaaattctg ggctgttgta atcatgagat ttatcatcca acacttttat
    13021 ttctactctt tttcctgtac tttttcccca ttcgtctgta gcttttaatg tcaatatgta
    13081 tgtacctact ctatttgtat ctataaaccc atcaacttct attggtaata ccttcccagt
    13141 gttatcttta gctactatat ttaacttgcc agtgtcaaac ttttcaccct tatatacctc
    13201 tgtacttcca actgtaattg ctgggggttg tccatttgac tttgaagcac ttatacattg
    13261 ttgtattacc ttctcatcta tttcacctac agaggttata ttcttagctc cttctaatac
    13321 agttttatcg cttccatcat ttactagtac cattggagag tttttagtaa gtggtgcagc
    13381 tgctattgca tctactaatt ggtatccatc tgatacatag aatccatctg cactattaaa
    13441 aaagtagtct attacgtttt tgttagtttc aaatcggtca gttccttcta ttcttactga
    13501 gtttgtattt ttaactagag gattactcat tatctcctct gaacctatac aatatgattg
    13561 aatatttttt acatcaaaag gcacactctt tccatctgta agtatgattg gagctccatc
    13621 tctagtagct actgatgata cactcattgc atctgcttct ccactatatg cattagttag
    13681 tagtacttta tcaacttttt ttatagttgc tatttcttta gctattaaat agcttgtttt
    13741 tagtctatct tctccaccaa ttcttttgac ttctatattt ttagaatcta gttctttttc
    13801 tactgattta cttatagtat cttctgtacc tattatatat gcttttttga tattttttag
    13861 acatctattt gtgtctgctg gtatcttatt ttgttgtgta aatagtattg gagcttttgt
    13921 agctcccgat aatccacttg cacttaatcc atctgcaagt gatttttctg tatttactaa
    13981 aattactgtt tcataagtct gtttatcagc tatctttgct gctgtttcat atctatcttt
    14041 accgtatatt ttttctacta ctgatgatgc atttacactt ttgaagttta ctaagattaa
    14101 tgatactgct agacctaatg ataatatttt tttgttcatt ttcatatccc cctgatgatt
    14161 tttatatttt atatttatat tgtgattatt ttccatttat tttctcttta ttttccatat
    14221 attatagagt atatatgata tgaatatatc tcgtctatat attagtgttt tattttatta
    14281 aatttaaaaa attattttta acttcttttt aaacatattc aaaattgaat ttatatttat
    14341 atatataaaa gatatctgct ttatttaaaa ttaaacttaa tatagctcaa attattatac
    14401 attttaacct caatattatt agattgttaa gataatgaaa ataaaataag aatgcattta
    14461 aatatataac tttatatcta aatacattct tattttctat ttacttaata tttatttttc
    14521 aattaaactc ttaatcttgt ctattacaga tgaggctatt cctccaccta cttcaaacaa
    14581 ctttgatgaa tttttacctt ttaatgacga ttcttgtgat ttatctaacg tatttgtagc
    14641 aagtataact ggtgaattgt ttttagctgc taatggtcca actgctaaag catctataag
    14701 tttatcttga tttgcaacta caactccatc tagcttagat tgagagtaga atttatctat
    14761 tactttggca ttcgtctctt gtctagtttg acctgccacc ctattgtttg atatatcttt
    14821 gtttgctatt tttccaactt gttcaatagc cttgttagat attttttcta ctccaccaat
    14881 aaaatatata tttgacacct tatttgattt aataaattgt tcagcttcat tatctacacc
    14941 atctttttgt gtaagtacta ttggagtttt ttctttacca gccagtgatg ctattgataa
    15001 tgaatcagct tctccatttc ctgctcctat atacaacttg cttacattat tcgtcttatc
    15061 tatttctttt gctatattaa tagaagtttg atatcttgta tctccaccta ttctttgtac
    15121 tgatattttt gaatttacag ctttgatagc ttcaacaact gaatttggca ttgagttgtt
    15181 tccacctatc acaactactt ttgatggatt tagccttttc aattcttcta cagttttttg
    15241 aggaagttta tcatttgatg ataaaagaat cggtgagttt tttacactag caagtggtgt
    15301 agctgtaagc ccatccacca tacttttatc ttctccattt actattacaa ctgtatctga
    15361 ttttgtccaa ccactttgag atattttgat agctgtctca aatctatcat caccttttaa
    15421 ttttttgact gtgacattag atgtagaatc acttgaattt cctcctccag agcttccacc
    15481 actagatgag ccgcctgaat tacttcctcc accattattt ccaccactac cattatctgg
    15541 tggtaattca tccggttttg ataattcatt ttcaactatg tattctaaac tttttggaag
    15601 tgtaacttca acatatttgt ttattgtaac ttttcttccc ttagttgttt tttgtgctaa
    15661 tccaagtttt aatattacat ttgaaccact ttcttgtgtt tctttactaa caatagaata
    15721 gtttatccta atattgttta ataaatattc aagtgcttca cttttctcta ccttatactt
    15781 ttcagggtca tttttactag aaccagttcc cccaatcggt tttacttcac tctcattaat
    15841 aagggtaaat attaatcctt catcagagct tatattttca taatccactg ttttgttgtt
    15901 atatgttaca atttttaaag ctggtttatc atttgttcct tttcctaaaa ctttatagtc
    15961 agcatttgag ttacttccag atttttttac agatattctt cctatattca atctatttcc
    16021 gtctagtaag tcttcatttg atgtaacata tatatctaat gtagttgtat tacttgattt
    16081 gttgtattct gctctacaag tagcatttgc atttccactt tttatctgag attttatatt
    16141 atcagaccaa gtaatctttt ctttctgctc attatctact acttcaacct caccttgtac
    16201 ttttatactg gcttgaaatg aatatactat gttttctact gagtccacag atatatctat
    16261 agtatttact ttctcatacg tttttgttcc ttgtaaaact ggagctgcat atgcacatgt
    16321 agcactacca gttacagcta ctgccatagt tgatactgct atagttctta taaaagattt
    16381 tcttttactc attaacaccc gtccttatct atcattaact aagtggataa atttacttat
    16441 ccacctagct tttatattta atttataaat taccctaaat ttatgattac atttatatac
    16501 tttactttta atatctacta ttttaaaact attctagtac ctaatcttat tagatataca
    16561 atgttagtgt tagtattttt acgtttttag agttccacct actatttatc tctaacaata
    16621 ttacccttta ctttattgct tacagttata accttcttat tactgatatc aatagaattt
    16681 cttgtagctt ttctagcttt actattacta tcagtaagac ttattgtctt taactcatca
    16741 taattcttag ctcctacagg tacatacatt gtatcactta caaatctttg acctactgga
    16801 gtatctcctt gaaggtcatt gtatctatat agttcagcct taaccttatc acttaaagaa
    16861 tcaaagtttt cttttggcat atagtaaacc catgtacctt tactgatttc acctagttca
    16921 cctttttctg gaacttctgc aaataaaagt gcttctccag atatagtctt attgttttta
    16981 tctataagta gtggtaaatt aaatgctgga tttccactgt attcacctgt aataactatt
    17041 gaacccgctg gaatcttacc tgtttcatct tcacttgtgc tagagtcatc actttgatat
    17101 acataatctt ctgctaattt tccaattcca ttagtacgag tttcgtctgc attattcatt
    17161 gtgccaattt ctatattatc acctggaggt cctattatat ctaattctgc aacttctata
    17221 ttagacttat tatttgagat tagttttaca tatctagctt ggtatgtcca aagtttacca
    17281 tctttattaa atgtaactct agcttcatta tcttggtctt ttcctccacc aactaaatct
    17341 tgtccatatt caaaagttcc ttgacttaca tcttcccagt tctttttatc attacttact
    17401 tgtattttgt aattagttaa aggattgtat gttgtgctag tattctttct aaagttaaat
    17461 aatcctttta atgagaactt cctagcttct gtctctggtt ttgtatattt tagtcctact
    17521 ataggtaatg tttctttcat gtctactatt atatatggat tttcctctac atttatatca
    17581 gggtcttttt gagggtcttt gttccactct gctttactta ttatctttcc tttatatgta
    17641 gtatttgcat cattatcttt tatattatca atttcaggat tttgtaatgg tccatgtgag
    17701 tcattttcag ttctaacatc accgtcagaa acagtatttg ttatgaatga ccatgctgat
    17761 ttatttattt tcccttcatc tgataatttt acagtaccaa cttcaaattc ttctgttgga
    17821 tttaggtgat aatcatatgc aactacctta tatgtaaatg ctctgttatt aagaggagat
    17881 atattatcag taaatttagt cttactattt ccttttgcat ccacaaatcc aactgttctg
    17941 tattttacct gtgttccatt ttcaccatct aaataatttc catcacttct tattatttcg
    18001 tatcctagta tcttatcttt atccttatct acatctaggt ctatagatat tttattagat
    18061 ttaactagag aaccactttg tattccatca gaaaaactag cacttacttt agtatctttt
    18121 gccatactag ctatattttc atttaaaatc tttcttctag cttcgtcatt tacatattgt
    18181 atctttcttg attctttttc gtagttctta ctatccatta tactgtttaa ttctggtgta
    18241 atttctactc cccatgcctt aaagtaatct cttaaatctt tttcaacaac acttgatgcc
    18301 attgctacta gcatttggtc ttttggcaaa ctattaattg ggtcactact tgaaagtgct
    18361 ctgtattttc ttgaaatctt tgcatagaat gtatcattac ttaaatcagc atctgagtta
    18421 ttctttaaca ttgaacccgt aaaatcatca tcataagcta gatgtaattg ccataacatt
    18481 ccaagccttt caaatacatt gcttggtata cctaagctat ttgaagttac atgctcatat
    18541 atcttatcca ttgttgaacc ttcaattctt gaatgtgtct tatcatcaaa ggtctgagca
    18601 agtaaagcaa gtacattgtt actagtttcg ctatatgtca tctttccaat atctgtaaca
    18661 tgtcctatct catgacctat tccccatcca aataagtttc ctcctgtagc ttttccacta
    18721 tcatctattt ggaaaggtac tccattcata agccctggaa ctgaaccata ttctactcct
    18781 acatgtaatc cagaagcata cataaatgct ccaataaaca ttctttggta ttttatgttc
    18841 atacgagatt ttggagccat atcattttta gttaagttaa attcattatc atctacagtt
    18901 ccattaccat ctaaatcttg tgttttaaat actcctcttt ctgagtaaac taaatccatt
    18961 atttgttccc atgcaagcat actattatat aatctatcta cttgtgtatt taaatcagca
    19021 tttccttttg atatcccttg atatacagct gttgcaggaa catttaatgt tactttatca
    19081 ctttcaatat ctgtagtgtt taacacacca gttttttctg aatatccata tgaattacca
    19141 acatttgttc ctggataata tggttctcct tttacagcat ctttatatct agctaattct
    19201 tctatatatg cttttatctt tttcttagat tcagaaactc ccgcaggact cttatcattt
    19261 attgttccat ttagattaag gtgtggtatc ttagtagctc ctgctacacg tacttttata
    19321 tctcctccac ttggagtatc ttcagcgtat cttatgtata aacttcctcc acattctata
    19381 tctaaactat gaagtttgct taattgaatt acattttttc cagtgttaag atttatttct
    19441 ccactcttat atgcaccaga ttctccatag tactgtgtat atatcaactt aggagttttt
    19501 ccacttttac ttccaacata tactgtgatt tcatctcctg ctctagcagc tactcctaat
    19561 gcctgccagt cattttgcat acctaaatta ttggaattta cagtatactg tccgttttta
    19621 tctttatatt ttcctaattt atttatttct tgatttacag tagttacatc agtaagtgtg
    19681 gctctatcat tatataagtc ttgagctaat tttaattctc tctcaataac tgtcttatat
    19741 ggatgatatt ctccactagc tttatctgga gtatttaatc tatcttttaa ttcagttatt
    19801 ttttcttgag ttacatcttc ttttaattca acttgtaggt catccataaa tagatttctt
    19861 acatcatctt ctatactgtc atactcataa aacttaagtt ctgatatatt agacttatat
    19921 gaataggatg aacaaacact tacttgtatc ttggtagcag ttattggttc ttttaatcta
    19981 accattacat acttattatt atttacaggg tctgtctttg tttcaaaagg aacatccccc
    20041 agattgtgta attgaccatt ttcatcccaa tatcgtacct caaagtcatt tattgtctta
    20101 tcagaaacat caaaacgagg tgtagccata aaagtatcca tagtataaga tttatcaaaa
    20161 gttattattg gtcctctatt cgttccctca gctgcattat atgttgggaa tgtccaatgt
    20221 gttgtaaagt ccccatctac tacattgaat ttatcaaatg gatttttatc actatattca
    20281 cttttgtcat atcctgctgg ataagtaaca tctacaatgt gatttgttgg tattccaaat
    20341 ccaccattct ctttaggagt attaattaat ctatagttag gtgttgttgg tgcatccatg
    20401 ctttcagttg tacctatata tgttttagac attccactag ttcccaagtg gttagtagct
    20461 gtcattctaa cttcatatgt tgtattatcc ttaagacctt ctatctttga acttgtccca
    20521 cgaataagct tatcattgta ttttatccaa gacccattag agcctttttc tttatagtac
    20581 aagtcaaaat ctttagcttg tttatgattt ttccagctta catcaagaga tttaaattta
    20641 cctttaacat ttataccttc tggtggttct ggttttgtgt ctggaacaac ttgaaattct
    20701 aatatactat ctgggctaaa ttgtataggt ttatagtttg aatctacatt ttctggtact
    20761 ccgtctaagt tttctggtgt tgcatcttta taaccactag accaatctcc atttaaagat
    20821 tgtatgctaa ccctatatag tccatatgct tctatatctc taacttctat tgtattttta
    20881 ctggtttgta attttttagt agataatact tttcccttac tatcaatttt atctagtata
    20941 agttcgtatg ctgatacatt tacttcatta ttccaataaa aagatacttt ttcatttcca
    21001 acagcagtgc tagtcgatat tttatttatt ttaggtatat tcatctctgg ctttggtatt
    21061 tctttatata cattgtttaa aaattcaact tttgatattt ctgcaagatt tctatcgttt
    21121 gctgttgtag ctgttatttt tatagttatc ttttttactg ctacttgttt accaagattt
    21181 attactatat cactattttg aacatctgca tatgtttcta atgttgactt actatatgta
    21241 gatgttgtag agttatcatc tttactgata ttaccctctt cttttggagt atcttcatct
    21301 gaattaggtt tatccattga tgaattttct ttatcattat ttttatcttg attggtatta
    21361 gagtttactt cttgtttatc gctattttcc tgttgttcat cattattttc atctttatta
    21421 tttgagttat tatcagtctg gtttatattt tcatctttat tatttacttc ttcttgattt
    21481 acttcttctt gttcgttatt tacttcctct tgttgctcct catcttttaa gtttttcata
    21541 tattctttgt tttcataagg aatctgttga acattaccat ctttgtcagt aacctcaact
    21601 attccttttg ctggagcagt accttctgga gcttttatat tgatgacttc catattaagt
    21661 gcttctgata aagctatatc cattactgct ggtttttcct cagatatttc atcatttttt
    21721 gaagatattg taactccatt attttctcca ctaaataaat tttctacatt accattaata
    21781 tctacatcac tatttccttt taattcaacc ttacttgtat ctactatagg attggtagat
    21841 actatacttt ctaggctttt tgcatcttca ctttgtccta aatttttctg tacataatct
    21901 aagtcaacaa tatctacctt tccatctcta tttaaatcaa attctctttt atttgaatct
    21961 atattctcta aaaccttatt ataatcactc ttatctactt taccgtctcc atttacatca
    22021 cccattaaga acaattcata atttaaaggt ttatttttat tatctacact tgctctattg
    22081 cttaataaga ctctttgtga ataacttgat atatcaatgt ctttaatttc tttgttctta
    22141 aatccatctc cagagacttc tacattgtat tttccaacag gtaaattatt aaatacaata
    22201 ttataatatg atatattctc atctttattt tttatttcac ttctacttgc agataatttt
    22261 tttatagtat attctatatt atctgtccca acatttactg ttcctgaatc tttttctcca
    22321 agctttatta ttccactatt gttactatca tcttttaatc gtaactgcat attagtcata
    22381 ctttctgaat cgctattttt tattggcagt gaaaaattta aatctacttc aagactcccc
    22441 cttaactttt ctgtaactga tttttcaact gcccttagct tcccctctaa tataggttct
    22501 gcaaaaacgt ttagtggtgc actacacata gatactgcta gtacacaaga tattgccttt
    22561 ttcatgaaat aacaatcctc ccttaataaa tatctaattt ttcatgaatt taaatactat
    22621 aagtttcaga caataaaaaa agacactcaa agagaatctt aattataaaa taaaaagact
    22681 ttactctttt tagcaactgg ctgatatggc tttaaaagct ttaatcccta tagttttgcg
    22741 tcattagatt tccctaattt tgccatttaa ttttcactac tttcttaccc attttatact
    22801 atatttaaac
//
LOCUS       DAEHWO010000063        22632 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEHWO010000063 DAEHWO010000000
VERSION     DAEHWO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.063"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            223..1659
                     /locus_tag="KNP54_002798"
     CDS             223..1659
                     /locus_tag="KNP54_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBF0893671.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            complement(1751..3625)
                     /gene="asnB"
                     /locus_tag="KNP54_002799"
     CDS             complement(1751..3625)
                     /gene="asnB"
                     /locus_tag="KNP54_002799"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBF0893672.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            3828..4502
                     /locus_tag="KNP54_002800"
     CDS             3828..4502
                     /locus_tag="KNP54_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBF0893673.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            4615..5151
                     /locus_tag="KNP54_002801"
     CDS             4615..5151
                     /locus_tag="KNP54_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBF0893674.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(5317..5937)
                     /locus_tag="KNP54_002802"
     CDS             complement(5317..5937)
                     /locus_tag="KNP54_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBF0893675.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(6251..8389)
                     /gene="vanT"
                     /locus_tag="KNP54_002803"
     CDS             complement(6251..8389)
                     /gene="vanT"
                     /locus_tag="KNP54_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBF0893676.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(8407..9213)
                     /locus_tag="KNP54_002804"
     CDS             complement(8407..9213)
                     /locus_tag="KNP54_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBF0893677.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(9210..10310)
                     /gene="vanG"
                     /locus_tag="KNP54_002805"
     CDS             complement(9210..10310)
                     /gene="vanG"
                     /locus_tag="KNP54_002805"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBF0893678.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(10571..11653)
                     /locus_tag="KNP54_002806"
     CDS             complement(10571..11653)
                     /locus_tag="KNP54_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0893679.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            complement(11703..12404)
                     /locus_tag="KNP54_002807"
     CDS             complement(11703..12404)
                     /locus_tag="KNP54_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBF0893680.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(12838..15369)
                     /locus_tag="KNP54_002808"
     CDS             complement(12838..15369)
                     /locus_tag="KNP54_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBF0893681.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(15477..16094)
                     /locus_tag="KNP54_002809"
     CDS             complement(15477..16094)
                     /locus_tag="KNP54_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBF0893682.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(16456..17340)
                     /locus_tag="KNP54_002810"
     CDS             complement(16456..17340)
                     /locus_tag="KNP54_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBF0893683.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(17531..18781)
                     /locus_tag="KNP54_002811"
     CDS             complement(17531..18781)
                     /locus_tag="KNP54_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0893684.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(19003..19767)
                     /locus_tag="KNP54_002812"
     CDS             complement(19003..19767)
                     /locus_tag="KNP54_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893685.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(19761..20486)
                     /locus_tag="KNP54_002813"
     CDS             complement(19761..20486)
                     /locus_tag="KNP54_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893686.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(20488..20856)
                     /locus_tag="KNP54_002814"
     CDS             complement(20488..20856)
                     /locus_tag="KNP54_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0893687.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(21032..22576)
                     /locus_tag="KNP54_002815"
     CDS             complement(21032..22576)
                     /locus_tag="KNP54_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBF0893688.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT         7803 a         3821 c         2364 g         8644 t
ORIGIN      
        1 tagcggtatt agattacaag cattattcta acttttttta tattaagacc ttacctttca
       61 tccctacacc taaaggagag ggcttttcgg caattttatt gtaattatat atcatttata
      121 taaacaagta catattttat tttgaaacta caaaattatt gtactatatt gttttaagtt
      181 gttttataat agattatatc atcttattat aggagaaaaa atatgatttg tactattaaa
      241 ccattaaaga tttcaataaa aaagtctact gaacctctaa ttgaatttat atctgatact
      301 acctataaaa ataagagttc ttcatatatt aaagaagtct actttacaag atatataggt
      361 gttgatgatt caattgataa atacatagaa aaaattaaaa atatagatac ttattttttt
      421 aataatccta caattcccta tattagatta aacaatctaa aaataaattt tgacaaagaa
      481 caaacagata agatgcttaa aatttttaat atttataata gttctaagtt taacagttgg
      541 gatttatata atatcgactt tccatgtaaa atagaaaatg acaccttaaa ttggactaaa
      601 aagattgcat ttaaaaatac tttagattta ttttccacaa gtatgccaaa ttgtacatcc
      661 tctatcatca aaaactttgc agttaaactt ttgtgttgga tagactattt tctacctaaa
      721 ttattttata acaaggtgaa gactactatt tcaccaaaga tagtatactt tggaaatatt
      781 aaaaggcaag aacttttttt cttatatttt ttatcacaac ttgggtgtga tattttatat
      841 ataaatccaa ataaagatat tcttgattta tatcctgaat gttcaaaatt ttctactcta
      901 tttgaacttt ctaggaagac tccaaatata ttagaaatac cttttgaaag gcatattaca
      961 aatataaatt acagtgaaaa taccaataag acttctccta ctacgaataa acctaactct
     1021 aaaaatacac ttaataacac aaatctaaca tctaaaaaaa ttgtacaaga tgaggaagta
     1081 gaactttctt atgaagacct tgcaaagtta tcagcttctg ttgttatgat tgttgtgtgc
     1141 aataacgaaa ataaaccgtt taagagcggt tctggagtag taataaataa tgaaggttat
     1201 atacttacga atcttcatgt agtcaatgat gggtattcat ttttagttag atttgaaaat
     1261 gatgataaag tttatacatc ttaccaaatt ataaaatacc attcagatta tgatttagct
     1321 gtgataaagg ttgatagaaa atgcaagcca atacctgtta aagtcagtaa aaaacctgtg
     1381 agaggtcaaa aaatagttgc aattggaagc cctctaggtc tttttaatac agtttcagat
     1441 ggaattattt cagcttttcg tgattttgaa acggttcaaa tgatacaatt tacagctcca
     1501 atctctagtg gtagttcagg aggagctctt ttagatatgt ttggaaactt actaggattg
     1561 atttccgctg gatatgatga tggacaaaac ttaaatttag ctgttgaaag tagtcttgtc
     1621 aaaatatttg ccaataattt tattgagata gtaaactaat caatcaaaat tctacttatc
     1681 ctattccata ataatcaaga gggtgaaaac attgcatgct tttgccctct gattaatatt
     1741 gaaaaaagta ttaatactcg acatttttat gctcaataaa taattgatgc catagacaaa
     1801 atgtaaatat agtccatatt tttctcgaat tatctctatg acctttaaga tgcgtatcta
     1861 aaagttttat tgcatatttt ttatctataa attcatctac atttgaatta taaatagttt
     1921 cctttacaat atcccctaga gaatctttta accaaactct tattggagtt ggaaatccta
     1981 attttttcct ttgaacaaca tgttctggga ctatttctct aaacgcctct ctaagtaaaa
     2041 cttttgtatt attcttattt attttttgct ccattcttaa attttttgcg acatcaaata
     2101 catctttata taaaaatggt actctaagtt caacctgctc agctgtagaa agtttgctaa
     2161 ttttttgaag tatatcgcct tgaagccatg tattcacatc tatatgttgc attttactta
     2221 tataatcgta attatttttt tgtgcatctc tatacaaatt agacaacagg tattcatata
     2281 tattcttttc cttatactta aaaaagaatc tttttacttc gctgttttca aaaacttttg
     2341 catttcctat atatcttttt tctaatggtg ttgtagctct ataaagataa tttcttcctt
     2401 ttatgtttgg cataagttct gaaactcttc ctaatatact tttaatataa gtaggtgaat
     2461 tgacaactga tttcatagta ctatactctt tatatatatt atatcctcca aataattcat
     2521 ctgctccttc tccagacaat gctactttaa catgtttacc tgcctcttta attaagaaat
     2581 aaagacctac ttctgaaggg tctgctatag ggtcatccaa agaataaatt acattcggta
     2641 atgattttat atattcatct tgtgttatat taatctggat attttctata cctaacttat
     2701 cagctgtttt ctttgctact tctaattcac tatatccttt gacactaaag cctgcagaaa
     2761 aagattttat atttggatta atttgtgaag ccacagtagt tataatagat gaatctattc
     2821 caccagacaa aaatgttcca atttctttct cctcttccat atgagttact attgaatcta
     2881 ctactatatt tcttatatca tcctcattca catctctatt gcctaagtga tttttagtat
     2941 aaaaaaattt tgtactactt ctaaactcaa gtttattata tctctttaaa gatagtatac
     3001 cattttctac cctaaaatag tgacctgctg gtatcagcct tattccttgt atcatagtat
     3061 cttcaggaag tacatattga aatgaaaaat aactttgtaa gcttctttca tttatattta
     3121 aatttttcat atattcaagt aaaaacttat actctgagga aaaaattatt gcattttcct
     3181 tatttatata ataaagtggt tttatcccaa ataaatctct tgctccaaat atactttcat
     3241 tttctctatc atagattata aagttgaaca ttcctttaat cttatgtaca caattcttac
     3301 caaattctat ataagatgct aataagactt caatatcatc atttgtagta aaattgtgtc
     3361 cttttttaat taattcttct tttatttcat gatagttata tatatttcca ttaaaaacaa
     3421 taacttttcc atctttttca aatggtttat ttccataaat agcatcaatt acattaaatc
     3481 tttcaaaatc aaaagttttt tcctcatcct tatactctat tctactagaa agtcttgtat
     3541 tatttacaga ttcttttatt ttaaatttaa tatcttcttt tttagatata tcacctttat
     3601 aataaattga aatattgccg tccatataat caaaattcct ttctgtcctt tagtcttatt
     3661 ctatatttca tagttttgtc tttggcttta aaacttattc aatttaaaat gaaattgcta
     3721 ttaaattctt ataaattatc tgttaatatt tcatattttt tttatttcta gaaatactat
     3781 attaggaggt gatttttatg aagaaaaaaa tattaatacc agttattatg tctttattta
     3841 taatctcaca gtgcataact tcatttgctt ttacacctga aaataacaaa tttaaggtta
     3901 aaccattacc ttatgcatat gatgcacttg aaccttatat agataaagaa acaatgaaac
     3961 tgcatcatga taagcattat caagcttatg ttgataaatt aaatgctgct cttgaaaaat
     4021 atcctgagct ttataattat tctttatgtg aattattgca aaatttagat tctttaccta
     4081 aagatattgc tacaactgta agaaataatg caggtggagc ttataatcat aaattctttt
     4141 ttgatataat gacgccagaa aaaaccatac cttctgaatc tttaaaagaa gctattgata
     4201 gagactttgg ttcttttgaa aaatttaagc aagagttcca aaaatctgct ttagatgtct
     4261 ttggttctgg ttgggcttgg cttgtagcta ctaaagatgg caaattatct attatgacta
     4321 ctccaaatca ggatagccct gtaagtaaaa acctaactcc tataatagga cttgatgttt
     4381 gggagcatgc ttactattta aaatatcaaa atagaagaaa tgaatacatt gacaactggt
     4441 ttaatgtagt aaattggaat ggtgctttag aaaattacaa aaatttaaaa tctcaagatt
     4501 aattaaatat taaaatcctt ttgaaaaaaa cttatgtttg ctatataata taataaaaga
     4561 tagtctaaat ttaccaatat aatgtttata gtgacgattc aggaggattt ttatatgata
     4621 aaagaaacac atgaaagggg aggttatata ttcgcacttt tgatactccc ctttataaac
     4681 aatctatacc tagttaaata cgatattgca tataaaatag tattaattat aatttatatt
     4741 tattttgcat atttaggttc tttatttcca gatatagata tgagaggttc ttacataagt
     4801 aaaaaattta tgttaatata caaattattt ggaagtaggt ttagacatag agggtttact
     4861 cacagtctaa ttgccttatt acttatttat agttttttta aatctctgac aatcttcact
     4921 aacaataata tagttttctc atgtttgtcc agtgggttta taataggata tctatctcac
     4981 ttgtgtcttg accttattac taaagaaggt attgaattgt tttatcccat taccataaac
     5041 atttctttac tacctataaa aactaactca aaaacagaaa aattcatatc taagctatta
     5101 aatttcatag ttattttttt gattggatat caattttata ttttattata gttgtagaaa
     5161 aaataaataa caatattttg aactaagtat aaataagttt tatatatttt agtttacaaa
     5221 agaactaaaa attttgtacc ttaatacaaa aaataaaacg tatcttaaaa taatttagta
     5281 ctaaatcatt ttaagatacg ttttatttcg tacaagctaa atcattttat catctttatc
     5341 attgtgatgt tttttatgat ggaaatcata attatgattt tcaagatttt tatttactct
     5401 atttccaatc ttccatgaca aaaacaccaa taatataaat gatgctatct ttaaaggact
     5461 tgttataaaa ccttctatat cacttgccac gtaacttata actataaaca ttacaaattt
     5521 tcctgccaac attgctggca caaaatcttt taaatctttt ttaccaaaag ctgatgcgat
     5581 agtaactaaa caaccgggca taaatggaca ggcatacgct ataaataata acttaaatcc
     5641 ctgtttatcc atccaactta ttgctttttc agttttacta tttctcaact tattaaaaag
     5701 cttactatca ttaaatctgc ttattaataa gaataatgaa gttgtcccaa gtcctgagcc
     5761 aatccatgat aacaaacatc caataaataa tccttgtatt gcagcatttg ctgtaactat
     5821 agcaacaagt ggtaaggctg gtataaagct ttctataaat gcacttaata agccgattat
     5881 tgtggctaac acccaataat tttgagtcaa atcaagtagt tcttgtatat actgcatatt
     5941 gcttttcccc ttttttaact ttaactatta ttatatactc tatatgttta ttatatacca
     6001 atctcaaaaa atgaatctaa tattaaaaag taaataatct atataagttt acagttaagg
     6061 tataattatt ttattatata ttataacaaa aaaggtgatg tttcaaaata aaaatctgaa
     6121 acatcacctt tttataactt aaattgtcat gtaagttata aaaaatatat attagacata
     6181 atattactaa aaatgtctag tcagagtaaa ataaattaca cagtacaaca aatattacta
     6241 tttaattgag ttacttcttt ataacattta accttcttcc tactctgctc aataattcat
     6301 tcgatatact acatgagtta tttgcaactt cagaagcaga taattcagat aaattatctc
     6361 ttcctattat tattgccgta ttaccaactt ctacattagg tatatctgta atatcaacag
     6421 caagttggtc catgcaaatt cgacccacta ttgctgctct acaaccattt attattacgt
     6481 aactttttcc acaggataaa tttctaggta taccatcggc atagccaata gataatatag
     6541 caattacgct atctctgctt gcaataaaga ctcttccata tccaaaacta tcatcttttt
     6601 gtatttttct aataagaatt acttgtgatt ttaaggataa aacaggtcgt aaatcaagtt
     6661 gcaatttagt cgtatcattt ggagaactta atatcccgta taatgcaatt ccaattctta
     6721 cataattaca cttaagattg ggataattaa aaaaaccata actactttga atatgtactt
     6781 taggaatttt tatacctttt tttaacagaa aatcaattaa cttataaaaa cattcaattt
     6841 gtttatttgt aaagtctaca tcttcatctt tcagactatc tgaaacacac aagtgtgtaa
     6901 atatgccaca tatatctaag tattttaatt taaatgcctt taaaattgac ctcacatcat
     6961 taacatcaaa acccagtctg tgcatacctg tatcaatttt aatgtgtgat tttatgttgt
     7021 atttctgttt gtttaaagag atagcatgat taaggtcaat aacactctgt gtaagattgt
     7081 atttatgaag ttcctttgcc cttattgggt tagtatatcc aagaatcaat atttctccta
     7141 gtattccata tcgacgtaaa tcaatcccct catctattgt tgctactgca aatgctttta
     7201 cacctatttg gtttgcacaa gtcgctactt caaaagcact atgaccatag gcattagctt
     7261 ttacaactgc catcaattca caatcttctg gcatagcttt ttgtatcatc tttacattat
     7321 gttccaaatt atttaaatca atttcaatcc aagctctatt ggtatttacc ttatgttctc
     7381 ctttcaagtc tttttttaga ggtttaagaa tcaatataat aattatagaa gctataaaag
     7441 atgctatact taccactata taatgaataa ggctattgtc aaccaagaca gtttgtattc
     7501 cgaatatttt agaaaacata cgaataacaa caatcatcat aggatgtata atataaataa
     7561 ttaatgatga tgttcgcaat aacctagctc gagaaccttt caaaaatgtt aaggctgtaa
     7621 ataagaaata catacatggc aataacataa tatacatgct atcatgacgc tgtaccccta
     7681 gtttatgtaa aaacattccc tcacataaca taagtaagaa tgatataaga aatccaatca
     7741 agctattttt agttgacata taattagatt tattagatat tattccacca agtatgaaaa
     7801 atacaggtgc aaaaaatata ccatttcgtg tataatctga tacttcaaaa atatacccat
     7861 ataaattctt taatagtggt attttttcta aaaaaccata ataactatca ccaaacatac
     7921 caattacata aataacaata gtgattacta gtgagtactt taaacctagt ctttttacaa
     7981 gaaagtatgc aatacttgca ccaataattg atgcaggtag ataccataaa tgatataaag
     8041 tcccatcaaa tacaatgtcc ttaataatat tgggcactaa attattcatg gaaaaatatc
     8101 cagtgtaaat atttaaggga atataaatta caatagctat cccgtaaata aataatacat
     8161 tttttagaaa agatttcagt ttattacaat tataattata tgttgaaatt agaaaaaagc
     8221 ctgatagcat aaaaaagaat ggcacagcaa tacgagcaat tatactagtt aacacaaagt
     8281 cagccatttt actatatgat aataatggag atgtatgaat tgcaattata agtaatgcag
     8341 ctataatcct aaaataatca agccctgcat aagatttatt cctaatcatt cttgttcctc
     8401 catttcttag tcctttctat ttctccaaaa tgtcacaata aaaccatcct tattgttacc
     8461 cgatatttga tatacacatt gttcaggtat agagattctc acttcttctt tagtatgaat
     8521 aggcacataa aagatttcta taattttttc tttatcttct atttttaaac aatttgtata
     8581 cgaaaatctc ttaatatatt ctatatattc ttcaagagcg agattcattt tattgataat
     8641 ctcagaatgc ggatatccca cataacgaaa atgccatggt tcttgagata ttcctgttat
     8701 ttcttctttt ttacactgat aacgctctat aaaaccataa tgtagtgctg ccttacgaaa
     8761 ctcattacaa ataccattat aaggaaattc agggcagata aaatctataa cttctttctt
     8821 taaccctaaa tcaatagcaa gccctgtctg atgttcactg tgatttggaa gtgctacaaa
     8881 ctttttagta aagtcttttc cattgtcacg cagagaactt gaatatatat cttgttgttc
     8941 ctctgcagta cgatatccac ttacaggtac tatttcattt attccacata tactttttaa
     9001 aatattttgt aaaatgtttg tagcttcacg tttcataaga atacttggaa accttgtatc
     9061 tacaggaatt aaatctatat cttcagatgt tttaactggt aaaaaagcat ttactagaat
     9121 tagattccca tcataaactt tatctttagt caataagata gtatttgtca ttttatcttc
     9181 tttattttta tctaataaaa tattattcat cattttatgt acacctcaat tatcttgtcc
     9241 aatatttctt caaaagacaa tccaatacct ttcatcatat ttggataacg actatgagaa
     9301 gtaaagccag gaattgtatt gacttcatta aaaataattt caccagatgg agttaaaaac
     9361 atatctactc tagcaaatcc agaacatcca agagttctat aaataatttt tgctgtctct
     9421 tgtattcttt tctcacaatc caaatcaatt ctagctggca tatgaatttt tgaacttttc
     9481 aatgtatatt tttctgtata atcaaaaaat ccttttgaca attctatttc atctactctt
     9541 ccaacaagta agtcatcgtt tcctaaaact gcacacccta cctcaaaacc atcaatattt
     9601 tcctcaatta ttacttcatt atcatgttca aaagccaagt ctactgctac ttgtaactct
     9661 tcttttttat aaattttact aataccaaat gatgaacctg cacgcacagg ttttataaat
     9721 aatggataag ttaagtcttt tgacagttca gccacattaa atttatctga gtattttagt
     9781 aatattgatt ttggtacttt aataccttct gaatgaacaa gtttatgtga tttgtctttg
     9841 tccatacata atgctgaaga aagagtacca catcctataa cctgtatacc tgccaattca
     9901 aataacccct gcactgttcc atcttctcca ttttttccat gcagtacagg aaacacaaaa
     9961 tcaagtttag tgtatttaat atcattttca catgattcaa tagcactatt tggaatatga
    10021 ttctgagaaa cagcatcagg aattaaaaat tcaataatac catttttgac acggttctgc
    10081 gaaacaataa ctggaattat atcagtatcc ctttcaaacc aagtgttatt ctggatatta
    10141 ttataatctc caatataatg ataccaatta ccctcccttg taattccaat tggtataata
    10201 tcatattttt ccgtattcaa attctcaagt actgcaaaag ctgattgtaa tgatacatca
    10261 tattctgttg agtttccacc aaatataact gcaatttttt tattattcat ctttgattct
    10321 cctttgttga tttatttatt tttatacaat ctacagaaac atgttaaaat actttttcta
    10381 tttcaaatcc aatcaacctt cacttacaat tgcatctgtt ccacataata tattttcaca
    10441 tttttctatt gatataatta ctgtatcaaa ataaaagcac tcttgttttg atacagtaat
    10501 tatatcaata acaagagtgc tctttattta tttatcctaa agaatttcct atttttttat
    10561 acttaaattc ttacaaattt cctacaatcg gaataataac cttaaagata attatattgt
    10621 tctcgctatg agctgttatt gtcccgttat gaagctccac tatttcttta gctatagcaa
    10681 gtcccaaccc agctctacca ctgtttgaat tacgagatgt atccaacctg taaaattgtt
    10741 caaaaatacg ctcaagtttt tcctctggaa tcgtattgct atgatttata aatttaagct
    10801 ttatataatc atcctcctgt acagctgtta tttcaatagt agtatcttca aaactataat
    10861 aaacagcatt tcgtaataag ttatcaaata cacgttgcat tttattaaca tcacacctta
    10921 tcatcatatt tggtgtaaca ttcagtgtat attttaaatt cttactcatc aaagtaggtt
    10981 taaactcata tgttagttgt tcaagcatac gagttaagct tactgtactg tattcaagtg
    11041 atatatttga taaattaaac cttgtaattt caaagaattc attaattaaa tcttcaagac
    11101 gctctgcctt atccaacgaa atagataaat atttttttcg cagttcttca gaaatctgac
    11161 tttcatctcg aagtagtgtc agatacccta taactgatgt aagtggtgtt tttaaatcat
    11221 gtgcaagata aacaataagt tcattcttac gttgttctgc catttgtgtc tcaaatttac
    11281 gttgttcaag tatatgttta attgagttta ttttcttttc tattgccaat aactctggag
    11341 ataaagccac ttctccaaca tcttctttga taagagagtc aataccttga tttatttcac
    11401 taaaatattt tgtaaaccaa tttaaataaa cccggaatat tataaaaaac acaatcacca
    11461 tagctagtat catgaagagc tccatgctat tacggaaaat ctgctgatat aaattcaatg
    11521 cagctttata ttccatacga aaagcatttt caaagaatga tactatccag atagaaaact
    11581 taccatacaa tataaaagaa tataaaatcc atatgaaaat aatggctata aatgccatta
    11641 aagctgttct cataaaaatt ttatttctca cttgagtaaa gtcaggattg actttaatat
    11701 ttttactttt caattgtata acctactccc catacagttt ttataaattt cgggttttta
    11761 gaaggttcat gaattttttc acgtaatcgc cctatatgag ccataactgt gttattatta
    11821 tcaagatatt tttctcccca tacagcttca aacaattctt cagaaggaac cacttttcct
    11881 tgatgttcac ataaatacca aagaatagaa aattcaatcg gtgttaatgc tacttctttc
    11941 ccaaataaac tacatttatg tgtttcttta ttgataatca atcctttaat atcatactca
    12001 ttaacaatta tcgactgttg ttcataagaa ttattatatc gcatatatct tcttaattgt
    12061 gtctttactc ttgcaacaac ttccaaaggg ttaaatggct ttgttatata atcatcagca
    12121 cctatggtta aacccattat cttgtctata tcttcaattt tagctgttaa cataatgata
    12181 ggataatagt atttttctcg aattttctgg caaatatgaa atccatcaat atcaggaagc
    12241 ataatatcta aaatagccat atccaaattt ttagattcaa tacattctag agcttcctta
    12301 cctgtataaa acttgtatac tgtaaaacct tcatttttta aatatacttc aattaaatct
    12361 gctatttctt tttcatcatc cacaatcaaa atattttcgt tcatagatta tttttcactc
    12421 tccttattat cgaggtcatc atttataata ttggtaaatt tacatatcaa ataattacaa
    12481 gcatatttgt aactaatttt tataagaaaa gaactactac atcagaatgt gttgatgcta
    12541 ctattggaac acaaaaactg agattaattg ttattataaa aactccccta acacgtcctt
    12601 attatcgcat aacaggtatt aactttcaat aaaaatatct atcagtcaaa cacaattcaa
    12661 tttattatac cagagacaat ccatataaaa aacaattaaa cctatgtatg taaccacaga
    12721 cattactaaa atttccatgt tattttatat aaaaattcaa aaaaggagtt gaatttaaaa
    12781 tttgattaga aaaaaatcaa ttttgagaca actccttttt attttaatgt atttaaatta
    12841 tagtatatca gccttcataa tatcctcaaa atcacctttt tcagatatta atcttatcaa
    12901 tttaacagta cagcttaaat catttataag tatagctcca actaatgaac catctttcat
    12961 aaataatttt ttatatattc tttgaccttc atcttttgat gaaatttctt tatcaaaatt
    13021 ttgtatatta ccaatactaa atacttttac attcattgca tctaatgaaa ctggatatac
    13081 ttcactttca aatgtcaaat tatctccact tgcatttgcc cctgctattt ttcccatttc
    13141 tactgaagat ggccatattg ctaaactaat atttcccact tgtgcaacat ctccacaagc
    13201 atatatatct ttaacatttg tctgtaatgt cttatctaca acaatacctc tatcaatttt
    13261 tacagatgta tcctgaacca tttgagtgtt tgctcttaca ccaattgaaa atactaccat
    13321 atcacagtcg acactatctc catctttaaa tacaactttt tgagcttttc catcaccttc
    13381 aataccatca actgctacac ccaatcttac atctattcct gtatctctta cacattgttc
    13441 taatatttta ctaccttctt tatcaagttg ttttgatagt atgctatcca tggcttcaac
    13501 tactactact tctaatcctt ttagtctaaa ttcccatgca gcttcaagtc ccaataaacc
    13561 gccaccaatc actacaactt tcttagattt ttctagtgct tcttttacac tatataaatc
    13621 ttttatattt ctaagagtaa acacattttc taaatcatgg cccttaattg gtggtataaa
    13681 gtttctactt cctgtagcta ttacaagctt atcaaattta atagctccat cattcactat
    13741 aatagtttta ttcacttcat ctaatttatc tacattcgtt cctaatatta ctactatatt
    13801 atttttatca taccaatctt tatcttccat gtagaaatct gaaccaagtt cttcatttat
    13861 accatcagaa agtgcaggtc tatagtaagt caactcatct tcattagaaa tcatagttat
    13921 cttacaagtt ttatttcttt ttcttatagc atctgctgca taaaaaccag ctgctccatt
    13981 tcctactatt acgaaatatt catcagtatc ttttctaaaa gtaacttcat cttcttcaac
    14041 ttctataaat tggtcttcct tagctccaca tacagggcat acactaggag cactatcacc
    14101 ttcaaaaact tcattacaaa ttacacattt aaatttctta gttttctttt tacttccaaa
    14161 agtagaattt aacttatcta ggaatttacc tgtataagaa tataatttat caatctcttc
    14221 atttgatggt ttaaagttaa cagcaaaagg ttttactgct gtcattctaa gctgacttat
    14281 tctctccata gcattttcta taccttctcc actccatcca tatgaaccaa atactgaagc
    14341 aacttttcca ccatgaagaa ctgggtttaa cgatattaat atatcccata taggctttaa
    14401 cgcatctcct aatattgttg gtgttccaaa taatacacct tgtgatactg ctatttttgc
    14461 caaaatatct tcttgcttat gctctattac atcaaataaa tttactttat agttgctatt
    14521 tttttcaata tatgctttta tagcttctgc cataatcttt gtatatccat gtgcagaaac
    14581 ataacaaatt gtaacttctt tttctaactt tatttgttca tttacactcc agttgtaata
    14641 aaggtctata atttttctag gattttcagt taatactgga ccatgacctg gacatacagt
    14701 atctatatct aaatctttta tcttttctat agcagttacc atagatggtt taaatggacc
    14761 cattatacaa tcataatagt atcttaaagc atccaagtaa tccttttctt cattttcatc
    14821 aagtgtattt actatcttat cattactata gtgactacca aatgaatcac atgttacaag
    14881 agttttatcc tcttttatat atgtgtatat ggtatctggc caatgaagca taggtacaga
    14941 gaaaaattct aaagttttgt ccccaattga taatgtatct ccatctgtaa ctgcaacata
    15001 ttcaaagtct ttgtttacga tttccttaag atatttaatt gctgtttctg aagctactac
    15061 ttttgcattt ttagctaaat ccaaaagctt ttcaacgctt cctgcatggt ctggttcagt
    15121 atgacttaca acaatatagt ctattttttc aaaatctata tttaaatcat ttaatctttc
    15181 aatataattg tcaaaatgct tatctttaac tgtctcaaat aaaactgttt tttctgttcc
    15241 ttttaataca tatgaattat aagtagttcc ataaggtgta tacataatta tgtcaaatac
    15301 tcttaaatca gggtcaagcg aacctaccca atataaattt tcttttattt ttagtgattt
    15361 caatgacata ccgtactcct cctaaaatag ttatttagtc tctttatacc ctgcttgtta
    15421 tattttaaac aaaatttatt caaaaaagaa attattttaa agatagttta aatcttctaa
    15481 tcttcttttt ctaccttcaa tacagttccc tttttagaat ctacttttat gtcatattca
    15541 tttttatctt tatctattct tattttataa aaagtaacat ctaaatcttt gtctaaactc
    15601 cattctttaa ctattccatt ttgttctttt aatgcaattt ccatagcttg ttgaggtgtc
    15661 attatgtcat ttaaatctaa tttttctttt ctagcaactc catttaaatc ttctgaatcc
    15721 aacttttctg ttttatcttc taatacatct tttgtattag catcaatttt catcttatat
    15781 tcattattat catctacacc ttccacagta taaacaaatt tatttaaatc tctctcaaga
    15841 cttaaatcta ctatatcagc atccttatat ttatctttaa atatgtttat tgcatctgtg
    15901 tatggcactt taaaatcttg ttccattaaa ttttcattat ttttttcatc ttttaaagcg
    15961 ttatttgatg catttgcctc cttttttgta ttatcttgtg cttgtcctga atccttagtt
    16021 ggactcccac tacatgcagt taataaaccc gctataagca tacttaccac taataaatac
    16081 gtttttttac acataaaaac cctccttaaa tatattaatt tattctatat tatgccctct
    16141 aaacccttta tttacccttt tatattaaaa attcctccta ttttatcaat tttaaaactt
    16201 tatatttact aaaattaaag ttacataaaa attatactgt ctcaaaatgg aaacaagcct
    16261 ctttttcatt gttgaaataa taaaaatata ttttatttcg tacaaaaaga gtgcctcatg
    16321 aactaaaaag ttcattttga gacactccca tttttttata tttttactta caaaataaca
    16381 gtacttatta attttttaca aaccttataa gtatatctat atgatattct taaatttaaa
    16441 cactatatta aaaaattaaa ttttgtttaa ttcttttacc gttaaatcca ttttaggata
    16501 tggaatcgta attccttctt cgtcaaacct aactttaacc tcttctagta aatcaagata
    16561 aattgtccaa taatcttctg tcttgcacca aactctagtt gcaaatttaa tagcattatc
    16621 tccatgttct actactccta taaatggttc tggttcattt attattaatt tatgattatt
    16681 aacaatatct ttaagtactc ttctaacatg tagtatatca tcttcatacc ctacactaaa
    16741 agtcaaatca actcgtctag tattctttgc tgaatagttt attagactat catttgatac
    16801 agaaccatta ggtataagta tctgtttatt atctggagta accaattgtg tataaaaaag
    16861 acctatttgt tcaaccgttc ctccatgacc tgctgcttct acgtaatctc ctactttaaa
    16921 aggtctaatc aatagtataa taaatcctcc agcaaaattt gatagactac cttgtaaagc
    16981 caaacctatt gctacccctg ctgatgctat cacagcagca aaactggaca aactcattcc
    17041 ccaatattcc agaacaatga ttataacggc aactttaagt acactcaaaa gaagagactt
    17101 taaaaacttt cttaaagtta aatcaatatc tcttttacta agtaataaca taacatggtt
    17161 tacaaatttt tttattattt taaatccaat agaaagtata agtatgccta ttataagttt
    17221 tactccgctt gtagtagccc attctagcag actttccatt atacctccca tatccatctt
    17281 attaatatct aaattattta aatctaactt gcttatatca tctattttcg tcgtatccat
    17341 aaaaaactcc ttaccttata ttttagaacc aatattatag tttaaagttc ttattttcta
    17401 tttaatataa tacaatacca tttgtacata gtaaacaaga tttatattcc aattatacat
    17461 attaggaaaa tgcaaactat ttgttatata tatgcaaaat ataatactaa attaaactat
    17521 taataaaaca ctatatagcc ttaaaatcat cattttttac ccctatatga gatgatacta
    17581 tagttataat acttagtact ataaatacta caaaaccttt tttatatcca tcaactatat
    17641 tatatgaatt tacttgtaaa gagatagcta taatcaaatt aataattcca cttcctataa
    17701 attcaaaagt attaataaca ctagttgcca gtccagaata aatttcttta tttttatact
    17761 tggcatcatt aaaaacctgt agatgtgaca taactataca tcccataata aagaatgata
    17821 ttggtaaaac tataattggt ggttttacct ggtatacaac tacaattaca atccatataa
    17881 acaaatctat cattgctcca aattttatta tattaaattt gctagacctt attttagcaa
    17941 atacaaaatc cataattatt gaaccaaata taaatccata tgtaaaaaat gatactataa
    18001 acgcagaaaa actcttactc acaccataaa cgtccattat gtatcttact ccccacaagc
    18061 ttataaatgc acttgtaaga ccaacaaaag agaacattat cattgaatta taccatgttg
    18121 atttgttctt tataacagac ttaataccat caacaatatt aaccttctct gacttttcat
    18181 agggttcagt atctacattg aatccatact cttttggtgt atctctaaca ataatataca
    18241 taaaacatcc aattacaaca ccaattatac cgattaataa aaatgaattt ctccaaccaa
    18301 caagttcaga caaaaacaca agtggaaaag tagcaagaac tccacctaaa tttcctacaa
    18361 atgaaaattt agctgttgca gaagcaaatt ctgacttatt aaaccatctc ccttgaattt
    18421 ttaaaataca aagtaatatt actgatgttc ctgcccctac aattacacga gaaatatatg
    18481 ctaattctat actttgaatc aaaccaaata aaattgaccc taaacttgcc attattattc
    18541 caagactgct aatttttctt gctccatatt tatcaatcaa aattcctgca ggtatttgca
    18601 taaatgcata tgcatatagg caaaaggatg ctatatttga aatttgtata gaattaaaac
    18661 ctaactcatt tgctaaattg tctgaaacaa cagcagttga catccttaaa aataatacta
    18721 aaacaaatga aaatgtaatt ataccccaaa cactccactt agcctttgta taacttttca
    18781 tatcttctcc ctcaaatcca tatattttta aattttcttg atataactta tataaagtgt
    18841 atagttattc ttacaaattt ttacacgcaa tatcattata caacatatgt atatatttaa
    18901 ctagaaataa aacactattc atattatata catgaattaa ctacataaat aataagagcc
    18961 atcttttaac attactcaaa agatagctcc atataaaaac atttattcta aatttaattt
    19021 tttatctaat ataaattttg tagcgaaaaa taacgctatt gcaactacaa gactaccaag
    19081 tattgcaagc ataaaactag gactctgata aagatgatat accatatttg tatcttcatt
    19141 tggtaagatg cttccaactg catctccaac aattgatatt actatattta tagctataaa
    19201 agaagcaaat gccactatgt ttctatgttt attgaatttt ggcaattgtc ccattgagat
    19261 tgatgtatat aataacaaaa taaatgatga atatgaaata aacattacta ctactaataa
    19321 taaaatatct aaaaagtttt cagaaatcca tttaaaacta gtgttaaaca aatctaaaat
    19381 ttcaggtagt aaaattccag aagtaccaaa aagcataaga actccaaaag tgaatactgc
    19441 aactataaaa ctaagtacag cgtatataag tgctgttata catttagata atataagtga
    19501 actagtgcta acaggaagag taaacattaa ataaccttca tcccccaaaa gattttttct
    19561 aaacctttga attgtaacta caatagttaa aactcctaat gccataaaaa gacttgttaa
    19621 tactagtatt cctattccct gtacctgaag tatatttgta ttcataaata ttccattaaa
    19681 tacagctact atcaatatgg ctatatataa cggtataaat attcttccac ttgcttttaa
    19741 ctcatatttt aataatttac ctaacattta aattcctccc taaataatgc atctatagat
    19801 tttccttttt cttctcttat tgcttcaacg tctccttgta acactatttc tccttttgat
    19861 atgaatatta tctcatcaca tatgttttct atttcactta ttaagtgggt agcaatcagt
    19921 aaagtactat cttcagaata attttttaat atagtcttaa gtatatatga ccttgcagct
    19981 gggtcaacac cacctatagg ttcatccaat atatatatgc tcgcatttct tgacattact
    20041 aaaataagtt gaactttttc tttagttcct ttagacattg tctttagctt ttcatttaca
    20101 tcaatatcta agcttttaat catctcattt gctcttctaa catcaaaatc actataaaaa
    20161 tcatagaaaa acttaagtaa atctgatacc ttcatccaat catttaaata agttctttct
    20221 ggtaaatatg aaactatttt tttagtatct atggatggtt tcattccatt tatcataatt
    20281 tcaccattat caggctgtaa taatccattc attagcttaa tcattgtact tttgccactt
    20341 ccattaggtc ctaacagccc gactattttt ccctttggta tatttaaatc aatatttttt
    20401 aaaacattct tagttccata actcttgttt acacctttaa attcaactat tccatcttga
    20461 gaaacattgc ttatattttt atccatttta taattctcct ttcagatttt ctgtaataag
    20521 ttttagcatt tcatctctat catatccaag cttttctaag gttactttta atgtatttat
    20581 ctccacatta gctatttcct ctttcatagc ttttattttt tccttatcat ctgttacaaa
    20641 tcttccttta gttctctgac tataaactaa accttgtctt tcaagttctg ttagagcctt
    20701 ttgcattgta tttggattaa cttccgcatc ttctgctagt gctctcactg tttctaattt
    20761 agatcctatt ttaatttccc ctgaaattat ttttaacttt aaatgttcta ctaattgtat
    20821 atatataggt ttgttattat caagttccca ttccatgttc atgcctcctt attatattat
    20881 tgtattaagt tgttaataca ataatataat aatacaaagt atatgtcaat tactttttag
    20941 taaaagtata aaaaatttta caaaaaaaat gaacactaca ttagagtcca tttttaacac
    21001 aatttattaa attctttata ttacagatta attaccctct taccaagtta gatacaatta
    21061 aatgttcaaa ttcttcaatt ggcattggct ttccaaacaa atatccttgt gccatatcac
    21121 actttacttc ttttaaaagt ttaaactgtt cttctgtctc aactccttct gatatgactt
    21181 tcatacccaa ctcttttgcc atttctatta ctttagtaac aattattttg cttcttttac
    21241 tattataagt ttccataata aatttttggt caagttttaa gatatccata ggaatttctt
    21301 ttaacatatt taatgatgag taccctgaac caaaatcatc catagatatt aaaaatccta
    21361 ttttttttaa attattcatt atatcaatta aaatatcaaa attatcaaat atgatactct
    21421 ccgttaattc aagttctata tactttgcag gtatattgta tttatcaatt atatttttgt
    21481 atgtttctat aaaattattg caatataaat gtatccttga aacattaact gaaacagtaa
    21541 ctggatttat tcctgcatca atccattttc taaggtatat acatacttct tcaagcacat
    21601 ataaatctaa atttataaca aaaccgtttc tttcaaaaaa tgggataaat tcatttggag
    21661 gtattagccc tttatcagga cgtttccacc taacaagtgc ttctgaacct tgtatctctc
    21721 ctgtattaag ttctatctta ggttgtaagt atataataaa ttctttattt tctagacttg
    21781 aaaacattgt attttccatc tctttttctt ttatctcttg gtcatgaatc ttattatcat
    21841 aaaatgcata tgaactttta tgtcctccct ttgccatttt atgaggtata ttagccctat
    21901 ctatgattga gttgatatct ctatcttctg gaagtataaa atagattcca caacttaaaa
    21961 ctaacttata tttttcttct tgattattat taaacaagtc taattcttca aatatagttt
    22021 ttaacctctt tgttatatct tcttcttcta tatatttcat aattataata aaattatccg
    22081 cagatattct tgcaaacatt tcctcttcaa atatattgct cttaataatc tttgttaaat
    22141 tacgcaaaat ttcattccca acttcatatc caaataaatc atttatatat ttaaatttat
    22201 caatatctat atataataaa gcatacttta cttgagtatt tttacatagt attttgttag
    22261 catcaattac aaatttatct atagtatttg ctcctgtaag attatctgta tatgctatcc
    22321 tttgcaattt aattttaaaa tttaatttat catatattat atagaatata agtattacac
    22381 atattatagc cataataagt attatttgta ttgcatgttt gctaataagc tgattattag
    22441 acacaataga ctcaaagtta tttatggagt tgtttttata gagtttgcat aaagaataga
    22501 ctggtgttgt gtatgtaatt tgtaaaatta tacaaataaa taaaaaaaac atcaattttt
    22561 tttgtaaatt cctcataaaa atttcctccc attaaaacac ctctatttta ttagcaaata
    22621 agtacatctc aa
//
LOCUS       DAEHWO010000064        22182 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEHWO010000064 DAEHWO010000000
VERSION     DAEHWO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22182
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.064"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            367..3021
                     /gene="adhE"
                     /locus_tag="KNP54_002816"
                     /gene_synonym="adhC"
     CDS             367..3021
                     /gene="adhE"
                     /locus_tag="KNP54_002816"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBF0893689.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3297..5516
                     /locus_tag="KNP54_002817"
     CDS             3297..5516
                     /locus_tag="KNP54_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0893690.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            5770..6432
                     /locus_tag="KNP54_002818"
     CDS             5770..6432
                     /locus_tag="KNP54_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBF0893691.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6803..8212
                     /locus_tag="KNP54_002819"
     CDS             6803..8212
                     /locus_tag="KNP54_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBF0893692.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8327..8602
                     /locus_tag="KNP54_002820"
     CDS             8327..8602
                     /locus_tag="KNP54_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBF0893693.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            9232..9543
                     /locus_tag="KNP54_002821"
     CDS             9232..9543
                     /locus_tag="KNP54_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893694.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            9545..11470
                     /locus_tag="KNP54_002822"
     CDS             9545..11470
                     /locus_tag="KNP54_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBF0893695.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFNCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            11473..11964
                     /locus_tag="KNP54_002823"
     CDS             11473..11964
                     /locus_tag="KNP54_002823"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBF0893696.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            12016..12579
                     /locus_tag="KNP54_002824"
     CDS             12016..12579
                     /locus_tag="KNP54_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBF0893697.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            12594..13571
                     /locus_tag="KNP54_002825"
     CDS             12594..13571
                     /locus_tag="KNP54_002825"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBF0893698.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            13558..13881
                     /locus_tag="KNP54_002826"
     CDS             13558..13881
                     /locus_tag="KNP54_002826"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBF0893699.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            13998..15776
                     /locus_tag="KNP54_002827"
     CDS             13998..15776
                     /locus_tag="KNP54_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBF0893700.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            15773..17146
                     /locus_tag="KNP54_002828"
     CDS             15773..17146
                     /locus_tag="KNP54_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBF0893701.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            17152..17820
                     /locus_tag="KNP54_002829"
     CDS             17152..17820
                     /locus_tag="KNP54_002829"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBF0893702.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            18097..19146
                     /locus_tag="KNP54_002830"
     CDS             18097..19146
                     /locus_tag="KNP54_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0893703.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            19242..20231
                     /locus_tag="KNP54_002831"
     CDS             19242..20231
                     /locus_tag="KNP54_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0893704.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKGKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDASIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            20236..21954
                     /locus_tag="KNP54_002832"
     CDS             20236..21954
                     /locus_tag="KNP54_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBF0893705.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAASLAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(22036..>22182)
                     /locus_tag="KNP54_002833"
     CDS             complement(22036..>22182)
                     /locus_tag="KNP54_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0893706.1"
                     /translation="NSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKIN
                     KQYQ"
BASE COUNT         8571 a         2598 c         4076 g         6937 t
ORIGIN      
        1 ttactttaac ttgttaatta agttttaatt ttcattttca aggattttta tttttaaact
       61 tgatagagta tcatattaaa aattcttttt ataaagtttt atttgcaaaa aatacaaaaa
      121 tataaacgtt aaaaaaataa cgttatcctt aagtttttag atgatttcat tagtgatttg
      181 cgtaaaaaat aaagtgatat ctagttaaat taagtatttg taaagctaga tattattagt
      241 agaaatgatg ttatattaga taaaaaataa aatgttaaaa aaataacttg aaaataggaa
      301 aagtaaatgc tataatgtta ataaattaac ataataaata aaaaactatc tcaggaggtt
      361 gttaaaatgg ctcataaaga acaagtaata atagaaaata aaaaagaaaa tgaagttatg
      421 tcagttggtt tagatactgt aaataacgtt gaaagcttag ttaaaaaact agcaaaaatc
      481 agagaagctc aaaaaatatt tgctacatat agtcaagagc aggtagataa aattttttta
      541 gcagcatctt tggcagctaa taagcaaaga gttcctctag ctataatggc acaaaaagaa
      601 actggtatgg gaattgctga agataaggtt ataaagaatc attatgcctc agagtatata
      661 tataatgcat ataaagaaac taaaacttgt ggtgttatag agaaagacga agcatttggt
      721 atgactaaaa ttgctgaacc aataggtgtt attgcagcag ttgtacctac aactaatcca
      781 acttctactg ctatctttaa agcactttta gctttaaaaa ctagaaatgg aataattttc
      841 tctccacatc caagagcaaa aaattctact atagaggctg caaaagttgt tcttgaggct
      901 gctgttttag ctggagctcc tgaaggtata ataggatgga tagatgagcc atctttagaa
      961 ttaactacaa ctgttatgaa agaagtggat ttgacccttg ctacaggagg tcctggaatg
     1021 gttaaatcag catattcatc tggaaaacca gctattggag ttggtgcagg taatactcca
     1081 gcaataattg atgatagtgc agatataaaa actgctgtaa actcaattct tgtatctaag
     1141 acttttgaca atggtatgat atgtgcttct gaacaatcgg ttatagtatt agaaaatata
     1201 tacaatgaag tcaaaaaaga atttaaagag cgtggtgctt atttattaga taaagatgaa
     1261 acagaaaaaa taagaaatat aattttagta aatggaggat taaattctaa aatagttggg
     1321 caaacagctt gtactatagc aaaacttgca ggctttgaag tcccagtaga tactaaggtt
     1381 ttaataggtg aagtagaatc agttgaaata gaagaagctt ttgctcatga gaaactttca
     1441 ccagtacttg caatgtacaa ggcaagtgat tttgatgatg cagttagaaa agcagaaaaa
     1501 ttagtagaag atggtggatt tgggcataca tcttcattat atattgatga tgtaaatcaa
     1561 agagaaaaac ttgataagtt tacttcagcc atgaaaactt gtagaatttt aattaatact
     1621 ccttcttctc aaggtggtat aggggactta tataatttta aactagctcc ttctcttact
     1681 ttaggatgtg ggtcttgggg tggaaattca gtatctgaaa atgtaggagt taagcattta
     1741 cttaatatta aaacagtagc tgagaggaga gaaaatatgc tttggtttag agcaccagaa
     1801 aaagtttatt tcaaaaaagg ttgtttagga gtagcattaa aagaacttaa agatgtaatg
     1861 aataagaaga gagcttttat tgtaacagat acattccttt acaataatgg atatactaaa
     1921 gcagttactg atttattaga tgaaatgaat attaagtaca ctacattctt tgaagtagaa
     1981 ccagacccaa ctttggaatg tgctaagata ggcgctaaag ctatgagaga atttaatcca
     2041 gatgtaataa tatctatagg tggaggaagt gcaatggatg caggaaagat aatgtggaca
     2101 ttgtatgagc atccagatgt agatttccaa gacctagcta tgagatttat ggatataaga
     2161 aaaagggtat atacattccc taaaatgggt gaaaaagcta attttgtagc tataccaaca
     2221 tcagcaggta ctggttcaga agtaacacca tttgctgtta taactgacca agatacagga
     2281 gtaaaatatc cattagcaga ttatgaactg atgccaaata tggctatagt tgattctgat
     2341 atgatgatga atatgccaaa aagcttaaca tctgcttctg gtatagatgc tttaactcat
     2401 gcattagaag catatgtatc tatgcttgca accgattata caaatggatt agctttacaa
     2461 gctattaaga gtatatttga atatcttcca cgtgcatatg ataatggtgc aaaagaccca
     2521 gaagctagag aaaaaatggc aaatgcttct acaatggcag gtatggcttt tgcaaatgca
     2581 tttttgggtg tttgtcactc tatggctcat aaattaggtg ctttccacca tgtaccacat
     2641 ggtgttgcaa atgctctttt gataacagaa gttatgaaat ttaattcttc agatgcacca
     2701 aagaaaatgg gagcattctc tcaatataaa tatccagaag cattaaagag atatgctgaa
     2761 atagcttcat ttttaggatt aaaaggaaat tctgatgaag agaaattcca aagtttattg
     2821 gtagctattg aagatttaaa acttaaagtt ggtattccta aatctataaa agagtttggc
     2881 gttgaagaat ctaagtttat ggattcaata gatgaaatgg taattcaagc atttgatgac
     2941 caatgtacag gagcaaatcc aagatatcca cttatgaatg aaataaaaga tatgtattta
     3001 aattcatatt atggaagata agtttgctat aaaatagata aaataaaaac tcttatacat
     3061 aaaacaaagt tttattgtat aagagttttt ttgtttgaga aaatggatag tttttattct
     3121 ttaatttaaa attcaattaa atagtgttat tataataata aaagaatgtt tttatggtta
     3181 ttatgttgat tttatgtgta acatttaaga atagttatat acaatataaa tgatgaattg
     3241 gtataaaaag gatatattat ctatatgaag tattgactaa ttaggggagg agtcgaatga
     3301 cagggagaaa taaaagtttt acattaatta caattctttt tttaacatca ttatttttga
     3361 caatggggta tatctatata gaagatacaa aacatcttct tatgtcagag gcaaaaatac
     3421 atataaaaga agttgcagta caaggctctc aactagcaca aagacaaatt gaaaaagatt
     3481 tagatgtttt aaatattttt tctaactatt atgcttcaaa tccagatata cctaatgagg
     3541 aaaaaatgaa aaatctttta gatgaaatgg aaaatcaaaa attttacact atggcaatag
     3601 ttgatataaa tggtaatgct gaaaatacca aaggtgataa gttttcagtg aaagatagag
     3661 aatttttcaa aaactcaatt aaaggtaaga agtatgtttc aagtccatat gttgatgaag
     3721 taaataagtc tataaagaag attgctattt cagtaccatt attaaataat gataaagtag
     3781 ttggagtttt atattgtact tacaatatca atactctgat gaaacttatt aatatatctt
     3841 tttatgaaaa taatagtata tcttatgttg taaaaaataa tggtacaatt atccttcatc
     3901 cacaagggga tagcctatca aaaaatattt ataaattgtt aaaacaggat aatgatattc
     3961 aagaagtaaa tagattaaaa aaagaattgc aagaaaataa aacaggtgca actgtattaa
     4021 atatgttgga agaaagaaga tatttaggat atgccactat ggataatggg aatagtgaaa
     4081 ataattatat aaaagactgg aatttaattt tttcaattcc agaaactgtt gtatttagta
     4141 attcaaaaca aataatcaac agagctgtat atgcagtgtt atctattgta ttaatattta
     4201 ttgcaattat tttttatata atttatataa aaaaatctaa tgaaaaagaa atattaagtt
     4261 tggcttatga agataaagtt acatatatag gaaatcaaaa taaattttat agagaatgta
     4321 gtaagtatct tttagataaa ccatctttaa attatattat agtatatttt gatattaata
     4381 actttaagat gattaatgat acttttggat atgaatttgg tgacaattta ttaattacaa
     4441 tagcaaaagc tttaaaagaa gaattaacag aaggtgaggt atatgcacga ctttcaagtg
     4501 attattttgc aattttctgt gattataaaa atggaagaaa taaaattata agaaaacttg
     4561 ataatatacg aagtaatatt gaaagtaatt tgagtatagt ctttgaaatt tctctgtgtg
     4621 tgggtattta ttttgttgaa gaaggtgaag tagatattca aaaggctgta aataaagcaa
     4681 atatggctag gtctgttgct aaaggtaaaa atataaatta tgctatttat aatgaagatg
     4741 ttaggaataa gcttagtgag gaatcaatga ttttagatga tataaaaata gcattggtaa
     4801 aaaatcaatt tgaagtgtat tatcaaccta agttttcact tgtaactgga gaaatgatag
     4861 ggagtgaagc actaataaga tggaatcatc cagaacatgg ttttataagt cccgcagtat
     4921 ttattccaat agcagagaaa agtaagttga ttttaaaaat tgggagattt gtatttgaaa
     4981 gggtttgcaa tgatttatat gaatggaaaa agcaaggtaa aaagatagtt ccagtttcag
     5041 taaatttatc tagggtcgag ttgtatcaac cagatattgt aaaatttatc aataaaacaa
     5101 taaaaatgta taatttaagt tcagatttca ttgaaataga gataacagaa actgtggcta
     5161 ttaatgagtt aaatatttta aagaatgttt taaatgagtt gaggacgtat ggattttcta
     5221 tttctatgga tgactttggt acaggatatt cttctattag ttgtttaaga gatatgccaa
     5281 ttgatatatt gaagctagat aagtcttttc ttggtggcat tgaacatgat gagagaagtc
     5341 gcaatatagc aaaatcaata gtgtctctag caaaatcact agatttagtt gtaattatag
     5401 aaggtgttga gagtaaagaa caagctgagt taatgaaaca atttggatgt gatttagttc
     5461 aaggatttta ttttgcacga ccaatgccag ctaagaattt tttagattta ctttaaaaca
     5521 aaatttgatt tttatataaa gcactattat gaatgcttga ttttaataaa tcattgctaa
     5581 ataattagtg tttttttatt ttatcaatgt attgtctaat ataaagcaaa aaataattgt
     5641 attttataaa aattatatta aaaataaatt tattttgcta ataaacatgt tattaacaaa
     5701 agaatagtac tataatgtat agatgataaa aactttaata aaaatttagt gtataggagt
     5761 tgtttaagta tgatagatat aagtattgat gacaaactta aggaaagatg gcctaatgct
     5821 aagctgggtt gcattcaagc aaaagtagca gtaaataaaa gctcagaaaa attaattaat
     5881 gaaataaatg agttttgtga tactataaat caaagtctaa aagttgaaga cattacgaaa
     5941 ctagataaaa ttaaagatgc aagaaatgct tataaagagc ttggaaaaaa tccaagtaga
     6001 tatagaacat cttcagaagc attggttaga agaattattc aagggaaggg tctttataca
     6061 ataaataata tagtagaaat aaacaattta atatcaataa aatcattata tccagtaggt
     6121 acatataatg taagcaaatt acattcacca gtatgtttta ctgtaggaga tgaaggagaa
     6181 cagtataagg gtattgggaa agaattaata aatatagaaa atcttcctat attatctgat
     6241 tcagtgggta aatttgggag tccaactagt gattctgaaa gagcaatgat aacagaagat
     6301 gcaaatgaaa tattaatttg tatattttct tttagtcaag aatctgatat tgaagaatat
     6361 tttggatatg ctaaggaatt acttaaagaa tatgcagatg gaaaagatat agaaactaaa
     6421 ataattaaat agaatctata taacaacgtt atgttaagct aaaattcaat ataaaaataa
     6481 gttaagataa agaaactaac acaaaattag tttctttttt aaaatagtag tttagtgtta
     6541 caaaaataga tagatagtcc cacgattatt aaaagtatgg taatatatta atatagcaga
     6601 gattgtgttt aagggatttt gaaagggggg atttataata atcattttat ctaaaagata
     6661 aaatggtttt atagaaataa ctatatattt aaaaatataa ataatgatac agtaatttgg
     6721 gtatataaaa taaggcatac atggttttgt ttaaaaacca ataaggtaca taggtaatta
     6781 caatgtaagg aaggatttaa ttatgattga tggaaaagag gtaaaacaag aaagtggaca
     6841 aaaaaatcta aaatttaaga tagctatagt agtaggtgtt ttgtttgtag cttatatagg
     6901 aatggcaatc ttttttagaa atcattttta ctttggaacg actattaatg gcgtaaaggc
     6961 ttcaggaaaa acagttgagc aagtaaatga tttgttaaca tctagtacta attcctatac
     7021 tttaaactta gaggaaagaa acaataagaa agaacaaata aaagcaaaag atattgattt
     7081 aaaatttaca ccagatgata aagttcaaaa gataaaagat agtcagagcg ctattggatg
     7141 gattggtgga atatttaagt ctaaagagta taataatatg ataactcttt catataataa
     7201 agatttacta gaaaaaaggt ttaatgcttt atcttgtttt gatagtaaaa atgttgtaga
     7261 acctaagagt gcttatccta agtatgatag cactaaaaac gcttatgtta tagtaccaga
     7321 ggtacttgga aacaaagtga aaaaagatga tttttataag ttagtacaaa actcaattaa
     7381 ttctgggaat acttctattt ctctggatga aagtaaagtt tatgaagcac caaacaacac
     7441 aaaggattca gaaaagttga aacaagctat taagacatta gataagtatg ttggtgtagt
     7501 cgttacatat gattttagtg accgtaagga aactttagat ggttctgaaa ttaataaatg
     7561 gttaaaagta gactcagaaa agaattatga cataactttt gataatgatg ctatggtaga
     7621 atatacaaga ggtttaagta aaaaatacag tacttttggt gactcaagac catttaaaac
     7681 tgccacaggt aaagatatta caatttcagg tggaatttat ggttggttga tagataaaaa
     7741 gaaagaagct gaagcattag ttgatgttgt aaaagctggt aaaaatgtta caagagaacc
     7801 tatttacata caaaaagctg tatctcgtaa taaagatgat attggaaata catatgtaga
     7861 gattagtctt tctggccaac atatgtggtt ctttaaaaat ggagaaatgc ttgtatcaac
     7921 agacgttgta acaggtgatt tagctagagg atttgctaca ccatcaggta tatatcctct
     7981 taattataag gctagaaatg tttcattaac tggtcaaggt tacagttcac ctgtaagtta
     8041 ttggcttccg tttaatggga acataggcat tcatgatgct acttggagaa attcttttgg
     8101 tggaagtata tataagtctt caggttcaca tggatgtgta aatacacctt tttctaaggc
     8161 aaagaaaata tatgaaaata tagaaccagg tacaccaatt attttatact agtaaatgtg
     8221 ttgctaacag ttaagcgaag tcatcttagt ttatttagga tggcttcctt tttatataaa
     8281 gcttattgaa gtttacagaa agactactta aaaggagaaa tacataatga atgaaaaatt
     8341 aactaaaatt ttagaagaag ctaagaatga tgatgaattt agaaaagaac ttataaaaac
     8401 aagagaacaa cgtgatgtta tggattcatt ttgtaaggtt gttacatcta gaggttatga
     8461 tatgacagta ggggaacttt tttctatggg agaagaatat acatccaatc tactgaaaag
     8521 tgtaaatgga ggagcagcat atcctattga agattggagt gattggtacg aggatttttt
     8581 tataatgttg tcgaatatat agagtaacta atgatattat ctacttaaga ttaatacatt
     8641 gccttaaaat aaaactatta gaactaggtg taagttttat caatctttaa aaatattgat
     8701 ttatttctaa ctagatataa aaaaattaga ttaaaaataa ggtgacaaaa atcgatatag
     8761 cttgatgatt tataaaagtt agataaaata gtgcgagata tttctaaaaa ttcaaaaaaa
     8821 acaataaact tcaatggtta gaggttgaaa aagaatataa aaaactttta tatgtaataa
     8881 attaaattaa aattataaaa aaaataaaat aaaaatttaa aatgtcgaca taacgttaat
     8941 tttaaaacaa aataacgcta ttgacaaact atatcgcttt aaattataat tattgaaaat
     9001 aatggtattt aaaaaccata ctcatgtcat agtctaaaag taagtcaaaa aaggatgtaa
     9061 atctaggcaa gtactattct aaaatatgtt ttattaagaa ataaacgttg aaaaatatta
     9121 attattatat aaaaatgctg tttatacttt aacaatgagg tagtaatcta attagaataa
     9181 aaaaatctaa ttggttatat acatagtaaa aaggtaagag aggtgatttg gatggctttt
     9241 gaaataataa aaagcattgt tgaggcagag cagacagcag acagtatcaa agtaaaagct
     9301 gttactgatg cagagtctat cagagctgat gctgtaaaca aatgtgaaag catatttgct
     9361 gatgtaaaaa aacaagcaaa gcttatggaa gaaactctta ttgagaaggc agtcaccgac
     9421 agtagagcag aggttgataa aatcttagct aatgctaaaa gtgaatgtct gaaaattgaa
     9481 aaaactgctg aagaaagaaa aagtaaggct attgaagcgg ttattggaaa ggtagtgaga
     9541 taatatggca atagttaata tgaacaaaat atctattgtt ggcttagaag ctcaaaaaag
     9601 ccagatttta aagctactta tgaaccgtgg gtttgttcag attgatgata gtgcctttct
     9661 tactgaggag gaggaattaa aaaattatct tgtaaaagat agtgaagaat ctgaagttat
     9721 aatgctagag cagaaaatgt ctcatgtaaa ccaagcaatt aatattgttt cttcactagt
     9781 gaaacaaaaa aaatccctac ttgcaccaaa aagagagttt aacaaaattg atagtgaaaa
     9841 agaagggcaa gtttatgctg aagctctgga gttaaacaat ttgcacaagg agataggtac
     9901 aataaggtct aacataaact tacttaacaa caataaaagt atgttagaac catgggtgaa
     9961 ctttgatatt cctcttgaaa atatggaaac taagtataca aaaactatac ttggaactgt
    10021 gcccataagc gcaaacattg atgctttaag agtaaaatta gaagatgaaa taccagaaag
    10081 tgttattggg attgtcaatt ctgacaagtt aatgaactat gtttatttaa ttactttaaa
    10141 agaaactttt gatgatgttt tagaagtttt aaaagaattt aatttttcag tggtttcatt
    10201 accaaatgaa gaaggtacac cgttacaagc tatcaagaaa tacaatgaaa tgataattag
    10261 acaggaaaac gtttctaagg acaaaacaga ggaaattaaa agacatgcag atagtataca
    10321 catgcttgaa aacctatatg atttttacac tatagaaaga gaccaaaaaa agattataga
    10381 gagacttgtc aaaacaaaaa caacattctg tcttaatggt tggttaccaa gcaaaagggc
    10441 agatgaatta attaaagaaa ttacagaaaa gtttaattgt tgtgttcaga ctgaagaagg
    10501 aagtaaagaa gaaggcttcc caattctgct tgaaaacaat aaattagtaa caccttttga
    10561 aagtgtaact aacatgtaca gctatccaag tacaaaagat attgacccaa atacaatttt
    10621 aactttcttc tttgttgtat tctttggaat gatgctaagt gacgccgcat atgggttaat
    10681 aattgcagta gtctgtggat ttgttgtata taaattaaag atacaaaaag gtgaaggaaa
    10741 tttaattaaa cttattggta tctgtggagt ttcaactact gtatggggtc ttatattcgg
    10801 gggtattttg ggggatttaa ttcctataaa agcattaatt aatcctttag aggatgttat
    10861 gacacttatg ggaatgtcgt tactgttcgg tattatccat atatatgtag gtttgggaat
    10921 aaaagcatat acattaataa gaagtggaaa ggtaatagat gcaatctttg acataggttt
    10981 ttggtatttg tgtataacag gtgtatgtct acttataata ccttttgttg caggggatat
    11041 aggtgtattt tcagaagtag gaaaatattt agcaattata ggtgctatag gtcttgtact
    11101 tactcaagga agaagcttta aaggtattcc tgttaagctt tttaaaggat tttcaagtct
    11161 ctatggtata acaagttatt ttgctgatat attatcttat acaagaatta tggcgctttg
    11221 tttaacaaca ggagttatag cacaagttat caacctttta ggagctatag ctggtccgat
    11281 acttgcagtt gtaattggtg ttgtaggaca cacaataaac cttcttataa atgcactagg
    11341 tgcatatgtt catacaagta ggttacagta tgtagaattt ttcaataagt tttatgaagg
    11401 cggaggagtt ccttttgttc cgtttaagta taaaacaaaa tatacaagca ttaataaaaa
    11461 ggagatgtaa atatggaatt tttaaacgcg ttaggaaatg gtcaattttt ggcaatatca
    11521 ggagctgcta tagcagcatt atttgcaggt atgggttctg ctaaaggtac ttcaatagca
    11581 ggtcaagccg cagcaggtgt tgtaacagaa gaccctagta aattcggtca acttctagtt
    11641 ttacaacttc ttcctggtac acaaggtctg tatggattta tcatagcttt ccttatttta
    11701 tcaaaagcag gaattattgg tggagatgca ataccaacat cagctcaagg tttacaactt
    11761 cttatggcag gacttccaat tggtttagtt ggtttagtat caggtatagc acaaggtaaa
    11821 gcagcagcag caggagttgg aatagttgca aaaagacctg aagaacttgg taaagctata
    11881 acatttgcag caatagttga aacatatgct cttttaggac tacttgtttc tttcttagct
    11941 tacaatggaa ttgcaattgg ttaattataa attataattc ataagtaaaa aaaatgaaaa
    12001 ggaggaagca ctcctatggg taatgaacaa aaaatgattg acagaattat agctgatgcc
    12061 aaacaagaag cacaagaaat attggataaa gctaaaagtg aagcagattt aaaagtaaat
    12121 tcagctaatg aaaaagctga aaaggaaatg gcttcctata caaagcttgc agaggcagaa
    12181 gcagaaaaag cggcttctaa ggaaatatca ggagcttata tggaggctaa aaagcaaata
    12241 ttatcaaaaa aacaagagat tttagaagag gtaattttag aagctaaaaa caaactttta
    12301 aatcttaaag ataatgaata tgaagagatt atactaaaca tgattgaaaa atcaaattgt
    12361 acagatgatt cagagatagt attatctaaa aaagataaaa aaacattaaa agatgtgcta
    12421 tcaaaaaaag gcattaaagt gtctgatgaa actagagata ttactggagg tttcatagtt
    12481 aaaaaaggtg acattgagta caattattca tttgaagcca taattgcagt agagcatgaa
    12541 tatattgaac aaattgcagc agaaattttg tttaattaag gaggggttaa aaaatggcag
    12601 aagaaaaaac ttatccctat gccgttgcac gaataagagt gcttgaaaaa cagcttctta
    12661 acagacaaat gtttattcaa atggcagaag ccaaaagccc tgaagactct ttaagaatta
    12721 tagctgaggc aggttatgct gatacatcaa ataataatat acataatttt gagaatattt
    12781 tgactcaaga attatcaaag acatatgaaa ttcttaaaag tctagctcct gaagaaaaat
    12841 ttgttgatgt atttctttat aaaaatgact atcacaattt aaaagtgctg attaaagaag
    12901 aaatttctgg tgtagatggt gagaaatatt taattgatgg aggtacaatt cctcttatta
    12961 agcttagaga atctttagca aatcgtagtt ttagtgattt acctaagata atgtcatcag
    13021 ctatattaga ggcatttgat gtttataata agacacaaaa tggccagatg gttgatattg
    13081 ttctagataa agcaaccttt accagtatga aagaaactgc taaagaaagc caaaacaaat
    13141 ttgtaataga ttatgttatg aaagtttgtg atttaacaaa tctaaagagt tttataagag
    13201 tcaaaaatat gaagaaagat tttgatatgt ttatgaatgt gtttgtttca ggtggctcac
    13261 ttgataagga aaaattctta gaagcttttt cctcagatac tccagcatca tgttttaaat
    13321 ctacttctta ctctgatgtc tgtaaaaatg gcatggatag tggttttact gtctttgaaa
    13381 aactttgtga tgactatctt atggaatatg ttagaggagc aaaatttaag cctcttacat
    13441 tagaaccact aattgcatat ttatatgcta aagaatcaga gataaaaaca attagaatta
    13501 ttttgactag taagcttaat aatatagacg cagatactat aaaagaaagg ctaagggatg
    13561 cttatgtata aggtaggagt agttggagat aaagatagca tcatgggatt tttagctctt
    13621 ggaatagata tcttcccagc ctatgatagt gacgaaatta aaaaaagtat acataagttg
    13681 gttgaagatg aatatgcgat aatttatatt acagaacagg catcattgct tgcaaaagaa
    13741 tcaatagcaa aatacaaaga ttaccaactt cctgccatta tagttattcc aggtattgga
    13801 ggaagtatgg gattaggtat gaatgaagta agagaatcta gtaaacgtgc tataggtgca
    13861 gatatattat ttaaagaata gatgaaagtt gaataaaaga caatctcaaa ttttattggt
    13921 gctaaatata tgtgctaata aaatatagga gggaatattt aaattttgat aaagtatatg
    13981 attgcaggtg agagaatatg aaaacaggca caattgtaaa ggtgtcagga ccgcttgttg
    14041 tagcggaggg catgagagat gcgaatatgt ttgacgtcgt aagagtttca gataaacatc
    14101 ttataggcga gattatagaa atgcatggag ataaagcttc tatacaggtt tatgaggaaa
    14161 cttccggtct aggaccaggg gaagaagtag tttctcttgg aatgcctatg agtgttgaac
    14221 ttggaccagg tcttatttca actatttatg atggtattca acgtccactt gaaaaaatgt
    14281 atgatatttc aggtactaat ataactaaag gtgttgaagt atcttcactt gatagaacaa
    14341 ctaagtggga atttaaacct aaaaaatctg ttggtgataa ggttgtagca ggagatataa
    14401 ttggtggcgt tcaagaaaca gcagtagtag aatgtaaaat tatggttcct tatggagtta
    14461 agggtactat aaaagaaata tattctggtg aatttactgt tgaagataca gtttgtgtta
    14521 ttacagatga aaaaggtaat gatatacctg taactatgat gcaaaaatgg ccagttagaa
    14581 aagaaagacc atatagagaa aagaaaacac cagattcact tcttgttaca ggtcaaagag
    14641 ttatagatac atttttccca atcacaaaag gtggggtagc agctataccg ggaccttttg
    14701 gaagtggaaa aactgttaca cagcatcagc ttgctaaatg ggcagatgca gatatagttg
    14761 tatatatagg ctgtggcgag cgtggaaatg aaatgacaga tgttcttctt gaatttcctg
    14821 aattaaaaga cccaagaaca ggcgagtcac ttatgcaaag aactgtgctt atagcaaata
    14881 catcagatat gccggttgct gcacgtgaag cttctatata cactggtatt acaatagctg
    14941 aatattttag agatatggga tatagtgttg cacttatggc agactctaca tcaagatggg
    15001 ctgaggctct tagagagatg agtggtcgtt tagaggagat gcctggtgaa gaaggttatc
    15061 ctgcatactt aggttcacgt cttgctcaat tctatgagag agcaggaaag gtaaattgtc
    15121 taggtatgga tgaaagagaa ggaacactta cagcaattgg tgcagtttct cctcctggtg
    15181 gtgatacatc agaacctgtc agccaagcaa ctcttcgtat agtaaaagta ttctggggtc
    15241 ttgatgcatc tttagcatat aaacgtcatt tcccagcaat taactggttg actagttatt
    15301 cactctatca ggaaaaagtt gatgtatggg cagataaaaa tgtaaatgat aatttctcag
    15361 ctcaaagagc tcaagctatg aaacttttac aagttgaatc tgaacttcaa gaaatagttc
    15421 aattggttgg ggttgattca ctttcagatg gagatagatt gatactagag gttactcgtt
    15481 ctataagaga agacttcctt catcaaaact ctttccatga agttgatact tatacatcac
    15541 ttcataaaca atatagaatg atgggactta tattaaaatt ctataagtca gcacaagatg
    15601 ctatcaagca aaatgttact ataaacgata ttatcaagct ttcagttctt gaaaagattg
    15661 gtcgtgctaa gtatgtagaa gaaggcgata tagatgcagc ttacgattca attgaagatg
    15721 aaatagataa cgagcttgca gaccttatta aaaagagggg ggctgaagaa ctatgataaa
    15781 ggaatataag tcaatacaag aggtagccgg tcctcttatg ttaataaacg gcgtagaagg
    15841 tgtaaaattt gatgaacttg gagaaattga actttcaaat ggagaaattc gccgttgcaa
    15901 agttctagag gtaaatggag atactgcact tgttcagctt ttcgaaagct caacaggtat
    15961 aaaccttgct gaaagtaaag ttcgtttttt aggaaagagt cttgactttg gagtttcacc
    16021 agatatatta ggtcgtgttt ttagtggaat gggtagacct attgatggag gtccagaaat
    16081 tataccagat aaaagacttg atataaatgg agctccaata aatccagcag cacgtgatta
    16141 tccggccgag tttatacaaa ctggagtctc tgctatagat ggacttaata cattggttag
    16201 agggcaaaaa cttcctatat tctcagggtc tggtttgcca catgccaatc ttgcagttca
    16261 gattgcaaga caggcaaaag tacgtggaac tgattctaag ttcgccgttg tatttgctgc
    16321 agttggtata acttttgaag atgctgaatt ttttataagc gattttaaag caactggtgc
    16381 aatcgaccgt tctgtagtgt ttgtaaacct tgcaaatgac ccagctgtag agcgtgtatc
    16441 tacacctaga atggcactta cagcagcaga ataccttgct ttcgagcaag atatgcatgt
    16501 acttgttata ataacggata ttacaaacta tgcagaggcg ttgcgtgaag tttcagcagc
    16561 taaaaaagaa gttccaggac gtcgtggata tccaggatat ctttatactg accttgctac
    16621 tatgtatgaa agagcaggaa aaatgaaagg gcatgaaggg tctataacta tgattccaat
    16681 acttacaatg cctgaggatg ataagacaca tccaattcct gaccttacag gatacattac
    16741 agaagggcaa attatactta gccgtgaact ttataaaaaa gatatacagc ctcctataga
    16801 tgttttacca tcactttctc gtctaaaaga taaaggtatt ggtaaaggta agactcgtga
    16861 agaccatgca gatacaatga accagctttt tgcagcttat tcaagaggta aggatgcaaa
    16921 agaacttatg gctatacttg gtgaatctgc actttctgag attgatttaa tgtatgctaa
    16981 gtttgcagat gaatttgaga aagaatatgt ttcacaagga tttagaactg atagaactat
    17041 tgagcagaca ttagaaatcg gatggaagct tcttagtatg ttaccaaaaa gtgaacttaa
    17101 acgtatccgt gatgaatatt ttgaaaaata tatgcctaag gagtgatatc tgtggctaga
    17161 ttaaatataa atccaacacg tatggaaatg actagactta agaaactcct taaaactgct
    17221 acaagaggtc ataagcttct taaagataaa cttgatgaac ttatgaaaca atttcttgag
    17281 attgtaagag aaaataagcg attgcgtgaa gaagcagaaa atgctcttga tactgcttat
    17341 aaaaacttta taatcgcaag agcagttatg agtcaggagt atctgggttc agcacttatg
    17401 atgccaaagc aatcagtttc agtagatgtt tctacgagaa atataatgag tgttgatgtt
    17461 cctgtgtttg actttaaaac tgaaaacaat caaagtgata tttatcctta tggtcttgct
    17521 tttacatcag gtgaattaga ttctgctatg gaagctttct cagatgctat gcaaccactt
    17581 ttaagacttg cagaaagtga aaaaagtgca cagcttcttg cacaagagat agaaaagaca
    17641 cgtagacgtg ttaatgctct tgaaaatgta atgataccaa attacattga gactattaag
    17701 tatatagcta tgaagcttga agaaaatgag agagcaagta ctactagact tatgaaggtt
    17761 aaggatatgg tgcttaaaaa agcacttgaa gaaaagaaaa aaaatgattt ggttgtataa
    17821 ttaaatactt ataaaaataa gtctaacatt ctactttata gaggttagac ttatttttta
    17881 tgtttaaatt aaaatgtaga tactataaaa attaatatat tgtttaaaaa cagactgtat
    17941 ttaactaaaa ataatatatt taacaaaaat ttctaaaaat taacgaactg ttaatttaca
    18001 cttaacttta tattaacaaa ttaggtgtat tatataaaca taagcaaaaa caataaaaaa
    18061 caaataaaaa aaggaaaaaa cacaaagggg gaagatatga aagaatttat atttacttgt
    18121 ctgtgcattg tagtgattac atttatgaca agttgcatat caacaacacc acaaactact
    18181 caaggaaaag gaaataataa acttacaata tatgcagcac tagaggaaga gcagatagct
    18241 tattatatgg aaggttttag agaagagtat cccaatatag atgtagagat agttatggat
    18301 tctcatggtg taatagcttc aaaactatta gcagaaaaag ataatccaca agcagatatt
    18361 atatggggat tatcagcaat gaacatgata gagctaaaaa aagatggtgc acttgaagca
    18421 tataagccta aaaattatga taaagttgat aaaaaattta aagatactga agatgatgta
    18481 tcttgggtag gaatgagtgt cccagagaca gcaatagtag ttaattataa ggaacttaag
    18541 aaactaggta tagatattcc aaaaagttat gaagatttaa taaaaccaga atataaagga
    18601 cttataacaa tgccaaatcc agcatcatct ggaacggggt atcttacagt atcagggctt
    18661 attcaaatga tgggtgaaaa agatgcttac aattacatgg ataaattaca taaaaatata
    18721 gccacatata cacactcggg ttcaaaacct gcgaagttag ctggctctgg agagtatcca
    18781 ataggtatta cacttggata tagagctaca caacaattat ctagtggaga acctatagag
    18841 gttgtatttc caaaggaagg ttcaggctgg gacttagaag caaatgcctt agttaaaaaa
    18901 gataatataa aaaaagaagc aaagctattt ttagattggg caataagtga ttcagctatg
    18961 gatagatatg cacatgaagt agcagttact tccataaaga cagataatcc agttccaaaa
    19021 ggttattcta aacaaccatt tgaacagctt ataaaagaag ttgatttaaa ctctgctgcc
    19081 aaaaacagaa gtacagtact taaaacttgg gaatcaaaat acggttcaaa atctgaaagt
    19141 aagtaaagtt taaattaata atttagatga aagaatttta gaagaaaaag taggatataa
    19201 aatttaaaat aaaaaaataa ctatataagg agagataaga tatgagttac ttaaaaataa
    19261 ataatgtgtt taaaagttat gaccaaaaaa gggttttaaa taatattagt ttggatattg
    19321 aagaaggaga atttctatgt ttactcggac ctagtggatg tggtaaaact acattactta
    19381 gaataatagc aggtcttgaa gatgtaaata gcggaactat aattctccag gataaagata
    19441 ttacaaattt agagccatca aagagaggtt ttggtatagt atttcaatca tatgcattat
    19501 ttccgaatat gactgcttat aacaatatag cttttccact aaaagagaga aaagtttcaa
    19561 aaggaaaaat agataataaa gttaaggaag tacttgaaac agttggattg actaatgaag
    19621 ctcataaata tcctaaagca ttatcaggtg ggcaacaaca gaggattgca atagcaagag
    19681 cattagctct tgaaccaaag tttttacttt tagatgaacc aatgtccgca ttagatgcaa
    19741 aggttagaca caagcttaga atggacatta aaagattaca aaaagaactt aatataacga
    19801 caataatggt aacacatgac caagaagaag ctataactat ggcagataaa atagctattc
    19861 taaatggagg agatataatg caaataggga ctccagaaga aatataccaa aatcctcaaa
    19921 acctatttac agctcaattt ataggagata caaactgttt tgataatgga gattctatat
    19981 taactgtaag accagaatat gttcaaatag agaaatcgac aaaagaaaac taccaaggaa
    20041 taatatcaaa tatagagttt agagggaatt tattgagagt tgaaataaaa gataaattaa
    20101 atgaaaattt cataataagt gatgcttcta taaaagagtg ggttaattta aatttagtag
    20161 aaggtgacct tgtaaaaata agtatagacg aaaaatacta tttaaagtat ccaaaagtta
    20221 aaggagcata agtgtatgaa taataatgct ataagttcta aaagtataag tcttaaatca
    20281 aaaatgaatt tagatataaa aaaatgtatg cttacagtat tagttatgtc tttagtaata
    20341 tttttattag cacctataat atatctattt gtacaggctt ttttagataa agatggagtc
    20401 tttgtaggat tacaaaactt tcaagaatac ttggcttctg aatctctatt aaattctcta
    20461 aaaaatacag tatttgtatc agttatatca actgtaatat cactaacact tgcattagta
    20521 tatgcatatg cattaactag aacaaagatt aaatttaaag gtttttttaa atcattagct
    20581 atgtttccta tgtttgctcc aacaatgatg catgcaatag gtctagtata tttatttgga
    20641 aatcaaggtt tggtaactaa tttacttgga gtgcatgttc caatatatgg agcagtggga
    20701 ataatattgg cacaaattat atatgtattt cctcaatcat ttcaaatact ttatatatct
    20761 ctaagttcaa ccgattatag actatatgaa gctagtaata ctatggggat aagcaagata
    20821 agagaattta taagcataac aataccaagt ataaaatact ctttaataag ttctgcattc
    20881 gtatcgttta cattatgttt tacagatttt ggagctccaa aggtgatagg aggagagttt
    20941 aatgtattat caatagatgt atataagcaa attatagggc aacagaatat gccaatggga
    21001 gcaactgtat caatattact tttaatacct gcaataatat cgtttatagt aactaaaaaa
    21061 attgaaaaaa atcaaaattc atatataact tcaaagtcaa ttccatataa ggttaaaact
    21121 aataagttaa gagatagtat tttaggaggg gttgtaggaa ttattgcatt tggtataata
    21181 gctgtaatgt taactgtaat cttatcttca ttaatatcag tttggccata tgatttaaga
    21241 ctgacactgg aacatttttc tatgaaaaac agtattgatg ggattaaacc atttataaat
    21301 tcaataaaaa tgtcactatt gacagctatt ctagggacga gctttgtttt cttatttgca
    21361 tatttgaatg aaaaaacaga aaaagctcca tatttaaaat catttgggta ttttttaagt
    21421 acattgccta tggcattgcc aggattagtt ttaggtatag cttatgtatt attttttaat
    21481 aaattagagt ttaattttat ggatacaata tacattaaga atttgtttaa tggattatat
    21541 ggaacattac ttataatggt tatatgtaat atagttcatt tcttttcagt agcatttata
    21601 acagctacta ctgctattaa gaaagtagat aaagaattgg atatggtagc taaatcaatg
    21661 ggaataaaca gcgcatcaat tcttaagaac gtaactatac cactttgttt gccagcagtt
    21721 ttagagaact ttatgtactt tttcctaaac tccatggtga caatatcagc attagttttt
    21781 atatatactg caagttcaaa agtagctgca atatcaattg tacaactaga tgataagggg
    21841 agtactgcac aggcagcatc actagctgtg ttaatattag tcacaaatat attagtgaaa
    21901 gtaatatatg aatttataaa gaatcgttta gaaaaaagaa caaactttaa ttaaataatt
    21961 tatcttataa aaacacaaat ttaaaaaagt ctattcttgt gatttattat ttaaagaata
    22021 gactttttaa atttattatt gatattgttt attaattttc cttttgttat catacatttg
    22081 agaatctgca cgacgatatg tatcaaataa agaaacatct actttttcat caaaaatagc
    22141 atatccaata gacattgata attttaattc attagttgag tt
//
LOCUS       DAEHWO010000065        22130 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEHWO010000065 DAEHWO010000000
VERSION     DAEHWO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22130
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.065"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(248..631)
                     /locus_tag="KNP54_002834"
                     /pseudo
     CDS             complement(248..631)
                     /locus_tag="KNP54_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      857..954
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1009..1185
                     /locus_tag="KNP54_002835"
     CDS             1009..1185
                     /locus_tag="KNP54_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893707.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            1411..1611
                     /locus_tag="KNP54_002836"
     CDS             1411..1611
                     /locus_tag="KNP54_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBF0893708.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            2363..2545
                     /locus_tag="KNP54_002837"
     CDS             2363..2545
                     /locus_tag="KNP54_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBF0893709.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIIF"
     gene            2616..3461
                     /locus_tag="KNP54_002838"
     CDS             2616..3461
                     /locus_tag="KNP54_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBF0893710.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(3685..3849)
                     /locus_tag="KNP54_002839"
     CDS             complement(3685..3849)
                     /locus_tag="KNP54_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893711.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(4391..4723)
                     /locus_tag="KNP54_002840"
     CDS             complement(4391..4723)
                     /locus_tag="KNP54_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBF0893712.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(4967..5608)
                     /locus_tag="KNP54_002841"
     CDS             complement(4967..5608)
                     /locus_tag="KNP54_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBF0893713.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(5589..5882)
                     /locus_tag="KNP54_002842"
     CDS             complement(5589..5882)
                     /locus_tag="KNP54_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBF0893714.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            6275..6334
                     /locus_tag="KNP54_002843"
     CDS             6275..6334
                     /locus_tag="KNP54_002843"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBF0893715.1"
                     /translation="MTEYIYYYNNKRIKKINLA"
     gene            complement(6850..7602)
                     /locus_tag="KNP54_002844"
     CDS             complement(6850..7602)
                     /locus_tag="KNP54_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBF0893716.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(7661..9316)
                     /locus_tag="KNP54_002845"
     CDS             complement(7661..9316)
                     /locus_tag="KNP54_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0893717.1"
                     /translation="MEYFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     YQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(10589..11668)
                     /locus_tag="KNP54_002846"
     CDS             complement(10589..11668)
                     /locus_tag="KNP54_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0893718.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIFNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(11752..12408)
                     /locus_tag="KNP54_002847"
     CDS             complement(11752..12408)
                     /locus_tag="KNP54_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0893719.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            12730..12936
                     /locus_tag="KNP54_002848"
     CDS             12730..12936
                     /locus_tag="KNP54_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893720.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(13089..13517)
                     /locus_tag="KNP54_002849"
     CDS             complement(13089..13517)
                     /locus_tag="KNP54_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBF0893721.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(13993..14931)
                     /locus_tag="KNP54_002850"
     CDS             complement(13993..14931)
                     /locus_tag="KNP54_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBF0893722.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            complement(15445..16257)
                     /locus_tag="KNP54_002851"
     CDS             complement(15445..16257)
                     /locus_tag="KNP54_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0893723.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFTKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLVEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(16283..16912)
                     /locus_tag="KNP54_002852"
     CDS             complement(16283..16912)
                     /locus_tag="KNP54_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0893724.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            complement(17256..18911)
                     /gene="ilvD"
                     /locus_tag="KNP54_002853"
     CDS             complement(17256..18911)
                     /gene="ilvD"
                     /locus_tag="KNP54_002853"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBF0893725.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(19235..19534)
                     /locus_tag="KNP54_002854"
     CDS             complement(19235..19534)
                     /locus_tag="KNP54_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893726.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            19794..20474
                     /locus_tag="KNP54_002855"
     CDS             19794..20474
                     /locus_tag="KNP54_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBF0893727.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            complement(20584..20841)
                     /locus_tag="KNP54_002856"
     CDS             complement(20584..20841)
                     /locus_tag="KNP54_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893728.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            21390..21761
                     /locus_tag="KNP54_002857"
     CDS             21390..21761
                     /locus_tag="KNP54_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0893729.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            complement(21758..21898)
                     /locus_tag="KNP54_002858"
     CDS             complement(21758..21898)
                     /locus_tag="KNP54_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893730.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
BASE COUNT         7631 a         3532 c         2387 g         8580 t
ORIGIN      
        1 ttattcaatt actgttcttt atagtcaata taaaagacag taatttatct atagtgttac
       61 ttatatttta tatatatggc tatttttcaa cattttacaa tatataacat ttattttttt
      121 aacttttgtc agtaaaatgt cagcaaaaca ctttatccac aatttttata taagttttcc
      181 acaacttatc accaatatta tccacataaa aaaggtagca cttatattat tagctacctt
      241 ttatttatta atctttatat ttccagcttt ttatccaact tcctatttct attatttttt
      301 cttcagttat ttcttctcca tcatgtaatt ttgaaattaa ttctgataaa ggattgttat
      361 gtaaacctct aaaaactctt tttccctcta ttttgagata ttctctctct tttattaata
      421 ctgtatagtg tacatgcctc ccaattctct atgatattaa aaaacctttt ttggttaatc
      481 tagctaaaag tataattgta gttgtatgct tccaaccata tgttttttct atttcatctg
      541 caacatcttt tgatattaca gttttataac cagtatgcca tatgcatttc ataattttta
      601 attctgtatc tggtaatttt ttatttagca taatatattc cttctttcaa tttatgtcac
      661 ttcttcaaat ttatctagct taaattataa taggagcttt ttagaacaaa aactatattt
      721 aatttttacc aggtactcta cgtgtttagt ctgtttttaa gtgtaaaata atgttcatat
      781 ctataaattt atttaacttt caaacaatcc tgttgaataa taactaattc tattgtatta
      841 ttttagttgt agaataaaac taaatcggca aaactagaga aatttagtga cgcaaagcta
      901 tagggactaa gacttatata aatatcttat gagttatgtc agccagttgc caaagagata
      961 gtgttctttt tgtttttatg aaagtttttt agggggataa taatttatat gtttggaaat
     1021 aaaatggata aatgtacaca tgtattgact gcttatatta gcagttcgta tgattattgt
     1081 aattttttag atacacagtt agatgatttt atattagagt acggagaaaa tgtagtagag
     1141 tcttgtttac accaagtaat ggtattggta agtaagtata attagataga cattgatttc
     1201 tagaaaaccc tttttagttt tatctacatt tatattaata tatagcaatg taaaacgttt
     1261 aaatatattt ttaatattaa gaataattaa aatgttaact aaaaaatata attaagtaga
     1321 catttctatt aatctatgat acaatagtat ttgtggtaat acacaattaa atcaagtata
     1381 tcttgatata ggttaatagg agtattttta atgaataatg gaatagtgaa atggtttaat
     1441 aatgaaaaag gattcggttt tatatcaatg gaaggtagag atgatgtgtt tgctcatttc
     1501 tcagctatac aaacttcagg atttaaatca ttagaagaag gtcaacaagt aagctttgat
     1561 atagttaaag gtgctagagg tcctcaagca gaaaatataa ctatattata atatatagat
     1621 ttttcgggaa agactctttt tagagtcttt ttttattgtt aatatatgta agataatcat
     1681 tggtgaagta aataaggtat attgagtaat gttcttgata gtttatatgc taatgaattt
     1741 caaaaaaata agcactccta taaaaagagt gctcttaatg taaatataaa ccttcattgg
     1801 tccagcctaa taccccgtat tctccaagtt ctaactattt tttatataca ttatcacttt
     1861 catccatatc taacacaatt atttcttctt tagaatcaat ttgtaaaata tgaggactgt
     1921 gtgttgtgac aattatttgt gtttttagga gaattgcttt taatgtaata aaaattttac
     1981 ataccacata gttgatataa aactataata attacataag attgtaataa taagacttat
     2041 ctttacatac cacatagttg atataaaaca atgaaattaa catacaagag actaagacaa
     2101 ttaaaatctt tacataccac atagttgata taaaacccca aaataaactt agcatctcca
     2161 atgtttacac atatacaatg ctcttaaaat tgcagtgaac gcgcaatagt gcaattgata
     2221 atacttatta tatattctca atgccttata tttcaactgc taaacctcaa tttgtcacaa
     2281 atatcgctca ctgcaaaatt tctatatttt tattatatca taacatataa ttaatatttt
     2341 caattaattt ttacatttaa ttatgtttaa attctataat aatgcaactt taatgtttct
     2401 ttctggaact aatataaaaa ctatttcaga aagattaggt catgcagata taaaaataac
     2461 tatgaatagc tactctcagt ttttagaaga gatggacaga gaagcatttg aaaatttgag
     2521 caaaatacta tttattatat tttaaagaag atgacttatt caatatttga tgctagaata
     2581 taattaataa aaatttaatt ataggtgatt gtattatgaa tattattaaa agcataactt
     2641 tactcttaac attattaatt gtgatattaa tgacaggctg ttccccaaga gaaagtgcta
     2701 gtgaagttgc aaaaaaatat attgataaga tgaactctgg tgactatgaa acagcatata
     2761 gtttattaag taaagatagt aaaaaaaaaa ttagtataga aaatcttgaa gaatttcaaa
     2821 atattttagt tagtacaaaa agaataatta gttataaaat aggtaaagaa aaaatcataa
     2881 aaaaatataa acatgatgga aaagaatata aaaatgttgt taaattagaa gaaactttta
     2941 atataaaaaa ccttctttat aaaaaagatg attctctaaa agtaaataga tattttgtag
     3001 ttgaaaataa caaatacaag ctattattgt atgaaagttt caaaaaagaa tttggtatta
     3061 atagtatgga ccttgctcaa cttaagctta atgattttgg actaaaatac tttaaagaag
     3121 ttgaccttat actaaaaaaa gctattgcta ttaatcctac tgattcaaag ctttattatg
     3181 cccaagcatg taattatatg aattttgatg gatttcctgg ttattcagat acaacatata
     3241 atgctttaga ttcaattaat aaatctttaa agtatttaga taaaaatgat tctgactaca
     3301 aaaaaaatgc aagtaatata tataacttaa aaggagttat tcttatgttt cacaaaagat
     3361 ttgatgaagc acaacaatat ttaaataaag ccttatactt taacaaagat aatgaagacc
     3421 caaaatataa tctaaataca ataaaaaaac atctaaacta gatatttaat ttttgaattt
     3481 ataaaatatt tttttatgta taattcagca ctgaatcata atttctacta aactaattac
     3541 aagtttaaat tataaagact tatttctata taaatattac tctataacaa taagtttctt
     3601 atttaaattt taaaatatta tctaaaaatc ataaaaaaga aggtataaag agctaccctc
     3661 aagctcaata taccttataa atatctaaac ttcatttttt actaattttt ctatatcttt
     3721 gataatatgt tctttagatt tttttccagc tatggcatca aaaattgcaa cagccttttt
     3781 ctctccaaac ttttctgcta catcattaaa gtctaaaaat ctaacacttt cttttggttt
     3841 accaaacata taacacctct catacatttt tatatattta ttataacttc tatagactta
     3901 tttttcacca ataaacgtta gacaaattag tccctttatt tttttaaact agctttacct
     3961 tcaaaattct taacaaaaac agtttattct actctataaa taaaaataga caatttaatt
     4021 tgtaggaaac tgataataga atacagtaaa taaaactttg tttaatctat ctgaaaaagt
     4081 tatctattaa aactgctatg aatttataaa gaatattcta gttcataaaa atacaaatat
     4141 gtaaatataa tcaccttaat attcaattta tttaaaataa aaaatgtata aaagatttaa
     4201 taatgacaat atactattct caatacaatc tatgatgtaa ataatttaaa actactatat
     4261 tatttaaaaa tttatattta tatatgcaat tctaaaaact taataagaag tgaacttaga
     4321 aaataaagct taatttcaaa gacttaaata gactattatt attagtctaa ataaactacg
     4381 tctatcaaaa ttatatatta aattcttcta aaatttttat tgcaaatctt gcgtttggat
     4441 atgtaataga cccgccacca attacaccta tttttatagc ttctataatt tcatctttac
     4501 ttgctccaga attaatacaa ccctcaatat gataacaaat acactcatca catcggctta
     4561 aaattgaaat agctagtccc attaattcct tatttttttt gcttatagcc ccttctgaat
     4621 aagtcttatc atcaagactt ccaaatactc taaaaaactc atctgtttcg cttaattttt
     4681 tattgtaaaa tcccctatat tctttcattt ctctagtatt catcttctac ctcctatgtt
     4741 tttcttataa gaatatcaca ccgtacttat attttcaata ttaaatacaa attttcattt
     4801 tatgttcatt agcctaattt atattatttt ttgaaatctc aataagttat catataagta
     4861 agattttttc agaactaaaa tagaaatctt agtaatttct ttattatcta tctcagttct
     4921 gaaatatatt attcttatcc aaacattatt atagtgatta attatattag ttatttttac
     4981 ctgaaatttt atacatcaaa taagaatata taaatggtag tattacaatt acaaagatta
     5041 caaagatatt ataaaaagga atattaataa atgcattaat aattaataat attccaccaa
     5101 taagccaaat ccatccagct aaatggtgtg tcttattcca attatcttca tcattaagag
     5161 tccatggtaa aattattcct actgagtaat ttcgtttaca tttaggaaga tagtttccaa
     5221 ataaaataac tattattcct aaaattaatc ctgtataaaa attagactcc aaactaactc
     5281 ctgttgaata taaaaccatc attatttgta taattactga aagtatagca actccccatt
     5341 ttgataaatt ttgtataaca tttgaaaaat tagctttctt aggctcattc tcaagtctaa
     5401 accatgtata caaatggata catagcatta acaatggtac accaaaagct gctataacct
     5461 ttggagcata attatctgga tttccataat tatcaaaatg aattgcaact tcatttggta
     5521 atctattata aaaatatatt gatacaataa atggtataaa acatattaaa gtagataaaa
     5581 taaattgttt atttatcgct tttttcatta tctttttctc ccttctccat aaattgtgaa
     5641 aaccaaagca tgacctcttc gaaaactgaa atatttattt cgtagaaaat aaagttctta
     5701 tactttgttt caaatatgag tcctgccttt tttagttgag atagatgata agaaattgta
     5761 gcattcgtca tattaaattt ttcactaatt tctcctgctg acattttatt ctccctcaac
     5821 ataaccaata tttctcttct tatagggtct gaaagagctt tgaatgtttc tggaaacccc
     5881 aacaccatca cctcgctatt tagaatttca tctaaataga atataacata acatccattt
     5941 tatttcaata gctatttaga aatttttcta aatagttatt tctaaatatt tattgaaaat
     6001 ttttatatta agattctcaa tttacttaag tcgcttttat ttaatcttac tttatctaat
     6061 ttttttaact taacaaaagt gtattgcacc ataattgtta aagcaaaaac ctaatgattg
     6121 aggtacttat atatataaca atacttttaa ttttaaatta aaagtagcta aacccaattt
     6181 aaaaagtagt taagtcctat ttaaatagaa aagaatgaaa cgagaaatat actgtataaa
     6241 agtacataaa aacatctact aattagatac aactataaca gaatatattt attattataa
     6301 taacaaaaga ataaaaaaaa ttaatttagc ataaccttgt taaatataga tttgaatatg
     6361 aatttaaagt tatgtaaaat taaaaataca ggaatgaaaa ttccattcct gtataaaatc
     6421 taacttttga gtctcagtac aatcttattt tgagacaatc ttttttgttt tatattttct
     6481 tatatttaaa atataacgca tatcttatgc aacatattca tatttttctt tatattcttt
     6541 catcgcatca ttccaagcgt cttgtactgt tacacctctt ttattagcaa ttttttgtgc
     6601 cagttcaatt atcttcatag ctcttcttga tatgttcata aacattcctc ctacaaatta
     6661 ccatatattt catatatata aatcaaggtt atatttttat gatatataat ccttctattg
     6721 taagattaca gtttatatgt gtattatata tgaactatat tagaagataa ttagaatttt
     6781 tataaagcta tatgattaga ttaaatataa aagctttaca attacttata aatttaaaaa
     6841 gtctataagc taaactaatg tttgatatac caattttacg accataaata atgccattac
     6901 taaaaatatt ggttttatca tctttgaacc tttctttata gcaactttag cacctacata
     6961 agctcccatt atcatcacta atgcaaacac tatagcaatt ttataatcta cttgaccatt
     7021 tatcatgaat aataacaatg aagttatatt acttgttaag tttaatattt ttgtatttgc
     7081 agaagcatgt aaaaaatcat atccatatat ttttataaat ccaaaagtca aaaaagttcc
     7141 tgtacctgga ccaaaaaaac catcataaaa acccattata agagccataa gcatccctaa
     7201 tcttaaattt ttcttattaa cagcttcaaa attatcttct tgacctaaat ttttagaaat
     7261 aaaggtgtaa atagccacta ttaaaatcat aaccacaacc aaaacattta atatctcttc
     7321 acttattgat aatacacatc tcacacctag aacactacca ataatagtaa atggtactaa
     7381 tttttttaaa aggttgttat taatttttcc agactttgca tatctatagg cactacttat
     7441 acatcctgct gatgctgcaa atttatttgt accaatggca agatgtactg gcactccaat
     7501 tgccataaga acaggcatgc ttataagtcc tcctcctcct gctatagaat ctacaaaagc
     7561 agctaaaaac ccccctatac ataaaaaaat aactgaaaac ataaaattcc tccatcattc
     7621 tctttcaatt tttcttacaa tatatattat ataatcttat ttaatactta ttatccagca
     7681 tattctttct atattcattt ggagttatac tattaaactt cttaaatatt tgtgaaaaat
     7741 aactactgtt attaaaacct actttcttac aaatatcact aatactcatg cttctatcta
     7801 acagatattt tttagattct tctatcctaa gaagatttat atactcagtt attgaaactt
     7861 tatttctttc attaaaaata gaactcaaat aatttggact tataaaaaaa acatctgata
     7921 tactattcaa atttatattt tctttataat atttttttat atattcgttt atattttcaa
     7981 ttagatttcc tttatctttt ctccaaaatg ctctattctt atcaatacac tctttggaaa
     8041 attcaaataa tacattccat aaatcttcat cactgtttac aagtgatatt tttttattat
     8101 atttatttct taaataagat ataagtttta aatcctctaa atctctaagc actgttctag
     8161 acaatacaaa tatcatttcc tgaatagtat ctctaacatc attatatctt aatttgtttg
     8221 tatctattag attataaaca ccttctaaat tcatattttt aatttctttt tcaatataaa
     8281 gttctaattc aaagggatat tcttttgaag aattattgaa catatctatc ggattaataa
     8341 tatactcttc ttctaataat ctactatttg cttttttaag tgcctcttca agtcttatat
     8401 tttcttttct actcttcaat atctcctcat cttttatact aagttgattt tcaaaaaaat
     8461 tcctcttagc tatttcctga ataaattcag acatcattaa taaattttct tttaatacat
     8521 ataatctact tttaggattt aatggaaatt cattgtaaat tttgtttatg tattttatat
     8581 caataccaga actacttgat aattcagata aatttttatc tatatcaata gacttatata
     8641 ctataaaatt accacattct atatatccaa ctatattttc ttctaatact ataggtatct
     8701 ctaaactgga aacaccatac tcacaatggt acactttttc aaagttatca ttatttatgc
     8761 ttttaacaag ttttttagta cactgtttta tatttttaca aatatcgcaa aatttatttt
     8821 ctttcttagt ctcaaatatt tctttatact ttaagtcata tacagatatt ctaagcttca
     8881 atatattaga tatttgattt gcaagatttt caattatgtt tacattaact aactcctgta
     8941 tattgttttc agaaaatact ataggtattt gtctcaaact cgaaaattta tgaggaacat
     9001 aagtaattaa tattactaaa tcaattttac cagtgtttat aatttcatgt tctgaatatg
     9061 gtgggcaata aactatagat gtttccttta tattgacctt tttaccatca attatttgta
     9121 ttccttctcc ctgaatcaca tataaaagct gttcttcact taaatgaaaa tgcttttctt
     9181 ggtagtttcc cggaaaaaat cttacaattc cagcactaag tctattgaat tgtgtttttg
     9241 atggttcgtg tatccacata acctctcccc aatcaaattt ttgtacttca ttatttgact
     9301 cactaaaata ctccataagc tcacctctta gtttttgtct aaatattttt tcttcccttc
     9361 ttatattaaa ataatatcat catcattaac tttcattact ataaaatcat catactcttt
     9421 taatactcct gtaattttag ttgcacttag tttactacaa ttcagttttt taatatattg
     9481 ataaattcta taattacttt tttattttgt aaaatcagtg ttttcccaaa ataattatat
     9541 ctataaatga aagtattttt actgcttaca tcaatatatg ttatcataat tttccttttt
     9601 attgcatata taaataactg tatataacat tgtccaatac tatatagaaa tacatctaag
     9661 aaagaatatt attaaattgt tccaattagt attatttttc ttatagaaat aaaaaaactg
     9721 ttggagtctt ttagaaaaat tattttttac ataccttttt tgcttagata gtctatcttc
     9781 acagctattt tgtatataca ctcttctagt tcatgatttt attttaatat cttgcttata
     9841 ttgctgaaat aattgaattc ttttatctat catattgtct cttatatcac aaacatattg
     9901 tttcttatat cacaaaaatg aaagcattct tatatcttca atatataaac ctgctttttt
     9961 taatcttgta ataaatatag gatactctat attctcttcc tagaaataac taataccact
    10021 tatttttcta ttatatagaa agtaataaat ctttttctta ataaaattca atagtaagtg
    10081 gaataaaatt ttatatgaat aagaacatta taaaaatact ttatacaata gtcaataaaa
    10141 gatattagct tcaaattatg ttaaagttgt attatttaaa gtgaaaaaac aaataaaaaa
    10201 gaaataatag tataagtaga aaaatatact taaaacaagg cgaagcctct cttgtatcta
    10261 aatcaagtag agaattaaat ctaaaaaaga aaataaatat aaaagatgac tcctgtacat
    10321 tacaagaatc atcttatggt ttcataatca ctccatggtt tttaactgtc tgatataaag
    10381 gtctcagttc actcatagca tgaccacctt ttccgattgc tgaccccgtc acttatggac
    10441 aaaatgtcca taagtgatag tcctctctta aaaccctcta aatagatata tctcaagcac
    10501 cgcattgaaa ccagttgctg gaaacaaact gaagcgttct ggaatagtaa aagaaattgc
    10561 caccatatcc acgttactgt cctagttgtt actttgctaa cttcggagcg atttcctcta
    10621 acaatacgca gtcaaattct gcctttttgc taagaaatgg cagatggtct gcatctggta
    10681 taaaaaaaat ctgtttgtct ggcgccacta tttcatcaaa aaatttcttc gctggaagat
    10741 aggggctatt atagtcattt tctcccatga tgtagtatac agggacctga tagtcaactc
    10801 cataatttct tatgtcagct tcttccacta aaaaccgcaa tacatcacct tgattgtcaa
    10861 tcgcatttgg attgaaaatg gccgtatttt ttaactctct caatgaataa tacggggttg
    10921 ccagtatact gattatattg cccaaatcca tatttataga aagcccatac ttgctttggt
    10981 atgttcttac tgtcataaga gctgccaaat agcttggacc atattttgct ggcggatatg
    11041 gtgcaatagc ttccagcgcc ttgatatctt tttgcttccc tgcagctttc accatttcaa
    11101 gtgtcttttc atagcccacg cgctcattgt ccaccatatt aacggtctgc gcaatcccaa
    11161 tgtacgcgct gtaatcctcc ggataggttt gcacagccat agttcccaga actgttcccc
    11221 agctatgacc tataaggata attttctcct tgttgaactc ttgcttcaaa tatgctgtca
    11281 cctcatggac gtcttgcaga acacgctccg cgctcatggt ctgcaaaact gctgccggat
    11341 cgttcgcaaa gtatgttttg cctacgtttc gctgatccca gttcaccaca gtaaaatcat
    11401 tttcccactc atactggtac agatgtaaaa atggcatcat tgaattacca ggacccccat
    11461 gaacccaaag gatgatgggg ttgtctgcgt tttgtccccg gatatataac gcctgctgta
    11521 tgccgccgat ctccaccatt tccatgcggt cgattccagg agcttctatt ttatggcttg
    11581 tacgtataat cgtgggggct atcagacgca aaccggcaaa cgccagaaca aaaacagcaa
    11641 ctagtatgca aagtgtgatt aatatcattt taagtacctt ctttcatgaa tttttttagc
    11701 catagatatc tcctctaaca ttaaaaaaaa tatgttgcta ttttagtttt gttactctac
    11761 ctgtcccatt ggtttccttt cataaaaaat attaattgat tctataatct catcttccag
    11821 gatatcaact cctatttgtc tcataagaaa ctgtaagaat tgaaaccgtt tacgaagtgt
    11881 aggaaagtcc ccctgaaata catctgtatc acaccaaaag ttaaagagca gcaaaattac
    11941 ctctgcgcat tcatctggga actctgtgat gatgcttcta tcctctatgc cttctcgtaa
    12001 aacatttgct aatattggtg ctagtttttt caaattatcc tgtgtaaatg ccagtatgat
    12061 atgcggactt tctatcgcgc ttgtaatcat gttactagat tcttttatca cctcatccgt
    12121 taaatgccgc ctaactaaac ttctaagctt ctcttttgct gtaagtccat gcatttcacc
    12181 gagccattga tttactgtct ctattatctg ttcaaagcgc ctttccatga ccacattaaa
    12241 aatatcttct tttgaactga agtgatgaaa aattccgccc tttgacattc ctgaagcatc
    12301 aacaatattt tgcatacttg ttttgtcata tcctttttca gcaaacaact ttgcagaaat
    12361 ggtaatgata ttttcaatag cttgctttgg attgttcttt ctagtcatta tataactcct
    12421 tcttattaaa aaccgactgt tggtttttat tatataagct attcctgctt ctgtcaagta
    12481 acattgtgtt tatggcaaaa caataaggtt tggtggttag acaggtatta attagactaa
    12541 tgcgactttc ccctagatgg aacccttggt aaatttgcaa tctttaccgg ctttgattat
    12601 atctgtaagc aaggcaggta tggccacacc tgccctgttt gcccctcgga tattcattcc
    12661 tatccctcct ctccttagcc attacaccaa aacgccgctc attgtctcca atggcggcgt
    12721 tttaaagata tgatttctca tgctgctgaa atatgcaaaa aatataagat gccctttatt
    12781 atttttccta caatagaaaa gaaaagtatt gaagaatggg ttaatattgg agcaaatatg
    12841 ctttgtttgg cacaagatac tacctttatc acttatgtta tcaatcaatt attatctttt
    12901 tataatgaga ttgtaccaat tcaaaaacaa cattaaatta taaatctaat tttatattaa
    12961 aagagactaa tattttatct atctctatta aggatatttt cttatgtatc ataatattag
    13021 tctctcttat tattatatac tgctatcatc attagttgct atttatacta tttttataat
    13081 atacaaattt attcagctaa cgttttgcct aattctatac actcatcttt tgcttcttca
    13141 tttgggtctt ccattgctgt aattccttct ccaccaataa ttgtagcacc agcattttgc
    13201 atacgttctt cccagtctct catccattca caatttcccc atccatatga accaaataat
    13261 ccaatctgtt tacctgatac catagattct aattctgaaa caaatggctc catatacccc
    13321 tcttctagtt gctctgctcc catagatggg caacctaatg caaatttatc ttcttctttt
    13381 aaatcacttg gtttcagtaa gctcacatct aaaacttctg gtgtcttacc ttttaacttc
    13441 acaccttcag ccacaaaatt tgccattttt tcagtatttc ctgttccact ccaataaaca
    13501 atatatattt tactcatttt tacctcctgt agtatttttt aattaatcaa tagttagtta
    13561 tagctaacta acatctaaaa aacaaaagat ttctttatct gaaatctctt tatttttcta
    13621 aatatagaat atcatggttg attttgaaat tcaatactta ttgataatat ttatcattta
    13681 tattttatat tcattttata atatcaaaac actgtatcgt atttctaatc tttcatagaa
    13741 aaatttctaa cttatagtac ttttgcatct cttataaatc ttttatatgt ataagtacat
    13801 agaaaaacac accttttcca gatgtgctat ctataatatc gtatatttat ttttcaattc
    13861 taactagcta atatgtttat aaattttatc acttaatacc tttatacatt gatgtaaaat
    13921 cttacaccta agtaattttt attatttgtc tcgactctat ataatatagc tattttatca
    13981 tcaaatcaaa aattatcttt tgctattatt cttgtattta taaagattta aatataagta
    14041 tccatttcct tgttccgttc taggtattcc aagcgctctc gtacatttta ttaattgtgc
    14101 atacagttca gcttcatcta aatctctttc aaactcctct cttgcccatt ctttaattag
    14161 tgctaatgag cctgatacgt atggtgcact catactggta ccactcataa tagcaagttt
    14221 attatccata taagtcgata taatatttct tcctggagct accaaatcta ttgtagtatt
    14281 tgaattacta aacttttcaa ccaaatagtt ctcatttatt gcacctactt ctattacctc
    14341 agcataactg gctggataac tatactcact tgtactagaa tcaccatctc cattattacc
    14401 tgctgcacac actacagaaa tattattttt tactgcttgc atgacagcat tttttaaatt
    14461 cttatcatct ttgtttcccc caagagacat agatataata tcaaccttgt tatttacagc
    14521 aaagttaata gcattaatta tactttgata tgttccagta ccatctttat ttaatgcttt
    14581 tgctattaat aatttacaat ctggagctac tcccataact tcattattat aattagatgc
    14641 agctataata cccgccacat gagttccatg accattaaaa tcctcatata tatttttatt
    14701 tccattactg tcatcactaa aatttgcacc accaattatt tttcctttta aaagaggatg
    14761 agatatatca caacctgtat ctattatacc aactacaata tttttaccag tataaccttc
    14821 atcccacatt cccctagcat tcatttgttt tattccatat gggaatttat tttttgcacc
    14881 tcttagattt tcatttattt catatggaat tagtttcatt cttttattca tcatatatcc
    14941 tcctaaaaat tttattgctt ataaaaatca tgaattttat tttataatag gtttataaat
    15001 caaattaaaa cctatatcta cttatttata tttatgatat attttttatt tttaggagtc
    15061 atattttatt gtatataaaa taatatttag ataactatat taaaaaatac atgtttgctt
    15121 atatacaaaa cttactaaaa tgtctttaat atttttgtat acaaacatta tattttttat
    15181 ataaaaagct cataaaaatt ttgattatat tttcataagt taacaaatgt gggtataata
    15241 tgaatttaca aaattcctct gtttgtataa gtgctttacc aatacaacaa tatataatca
    15301 cattgaagct atatttgtat ttatagtaga taatgtatca aaaattggtt atgaatagta
    15361 aaaataccag ttaagcatat tttcatgttt ctatttttaa cattaaattt ccaatcttca
    15421 tatgtatatt tttaacaaag gtgtttactt atttaaaaac tctaaaactc tttcattaaa
    15481 atcctgtgct tcttcatatg tagcgtgtcc caatccctca tagataaata tttcgctttt
    15541 tttaattttt tctactaaat gaaaagaagc attatttcca acaattttat cattagcacc
    15601 tcctataatt aaggttggac atgttatttt atttaattcg gaaaaggcat tatgttctat
    15661 gcaagaggtc gcttgaataa taaatcgttt aaaatccttt ggtttaccta cttttcctaa
    15721 aaaaggaata aataattggt atttttttaa atatctttca gaataggatt tctttgctgt
    15781 gtcaatcatt aaatcattgt aattctgctt cttcgccata tcaatccaac tacaaataac
    15841 attttggata gtatcatttt gctttgaaga agtaactgcc aacacaagtt tctcaactaa
    15901 ctcaggataa tcaattgcca gatattgagc tatcattcca ccttgagaaa cacccattac
    15961 ttctgctttc ataattccaa gttttttcat tatatctgct tggtctttag ccatatccct
    16021 tgtggaatat ttttctgtaa tttgattttt tctactaaat acataaacct tataatcttt
    16081 tgtaaattgc ttatatctaa aagcaaaagc aatcgcctgt atttttccat gtaaaggaaa
    16141 taaaccatct cctaatcctg gtaaaataat tagtgtcttc ttaccactac caaattcaat
    16201 ataattcact gtattacttc ctatcatcat ttgacaactt tttgcattat aaaacatagt
    16261 ctattcctca cttttcctat tatcattgtt taaataaatc tttaaatttt tgaataccat
    16321 actcatcaat tagaggaata tccatttttt ttaacatgaa taataaaaaa tccaacctat
    16381 tacatacttc actgtattca cgtttaaata atacagggtc aagtaaaata tcaatactaa
    16441 aaacgagcat ttcagctaat tcctctggat attcacaaga aaattcttta ttttcaacac
    16501 cttgtttaat tatcttagca atattgggtg caactacatt gttgagatta cgaacttcct
    16561 ctattaaagc gaatgggatt ttttctaacc agctacaatg taccattttt ctacgtgtgt
    16621 aatcattcgc actatgaaca accaattcta ttattttttc atttgctgta agggtgtcat
    16681 cagcaacaag atgctctaaa aaattattca tttgtgagta aagttctttt gtgacacttc
    16741 tcagtatatc ttctttagtt ttaaagtgat gatacattgc acctctagat agaccagata
    16801 aattgataat atcttgtgta gatgttgaat catatccttt agacgaaaat agtgaaaatg
    16861 ctgattggat aattttttct ttactatttt tacttttttc ttctctattc atatttccct
    16921 cctaaaaaca gactgtctgt ttgtttttta ttatacattt taatatttat tatgtcaaga
    16981 attaacttac tttcaatttc ttcatagttc agaaggaacg aaaagcattc cacatcaaac
    17041 ttttaaaaag ttgtattacc tcaacaaggt ctaaaagata catctctatg ctgtactcgt
    17101 attccttata atagagatgt attgttttca aagataatca agattttgct atgtttttca
    17161 tacaaaataa aaaggatacc tcattagtgc tataacacct aagatatcca attaatattt
    17221 tcttaacttt ttctaattta cataaatata gtctactatt ttaaaactgc tcctgtattt
    17281 gctgatgtta ccagtttagc atatctactt aagtatccat gctttatttt cggttctaaa
    17341 ggtttaaatt ttaattttct attttctatt tcaacttcat ctacttttaa ctctaatttt
    17401 ttgtctggta tgtttataga aattatatct ccttcttcaa ctagtccgat taaaccacct
    17461 tccatagctt ctggagaaat atggcctatg gatgcccctc tagttgcccc tgaaaaacga
    17521 ccatcagtaa gaagtgctac atgcttatca agtcccattc ctgcaactgc tgatgtagga
    17581 gatagcattt ctttcattcc tggaccaccc tttggacctt catatcttat aactataaca
    17641 tcacctttgt ttattttttt accaaaaata gcatttacag cttcttcttc tgaattaaaa
    17701 actcttgctg gtccttcatg aactaacatt tcttctgcaa ctgctgactt ttttacaaca
    17761 gctccattta gagcaagatt tcctttcaat attgcaagcc caccttggtt actatatgga
    17821 ttctttaatg tatgtattac ttcttcattt tctatttcac aatttcttat attttcccct
    17881 atagtcttgc ctgttacggt tttgcaatct aaatttattc catttatctt tgaaagttcg
    17941 ttcattatag ctggtattcc tcctgccata tgtaaatctt caatatgatg ttttccactt
    18001 ggacttaatt ttgttaaaca aggagttttt tcacttattt catcaaaaaa atctaagtta
    18061 agctctattc ctgattcata agctattgca ggtaagtgaa gtactgtatt tgtagaacca
    18121 gccattgcca tatccacagc tatagcattt ttaaaagcat ctattgttaa aatatctcta
    18181 ggttttatgt cgttcttaag taactccata acatacatac ctgcatattt tgctatcctt
    18241 tttctttctc cagaatgtga cgcagcagta ccattatatg gtatacccat gcctaaagct
    18301 tctgttaaac aattcatgct atttgctgtg aaaagaccag aacatgaacc acatccagga
    18361 caagagttca tggctaactc ttctaattct tcttcactta ctgttccatc tttacatgct
    18421 ccaacaccct ccattgcaga gttaaaatca tatacttttc catttttttt acctggaagc
    18481 ataggccctc cactcacaac aatacttggt atattaagtc ttgcagcagc cattaacata
    18541 cctggcacta tcttgtcaca attaggtata agtaccaaag catcaaaacc atgtgccata
    18601 gccatagctt ctattgaatc tgctattaat tctcttgaag ccagggaata attcattccg
    18661 acatgcccca tagctatacc atcacatacc cctatagcag gaaattctaa tggcaaacca
    18721 ccactcattc ttactccatt ttttgcagct tctgctattt catcaagatg cagatgacca
    18781 ggaatcacct cattttgtgc atttactata cctattaatg gtctttcaat ttcttcttta
    18841 gtaagaccca ttccatacat taacgctctc tttggagctc cttctattcc tttttttata
    18901 tcacttctca taatattacc tctttcttac ttttttaaat tttcataata ttattataat
    18961 atatttttct attaattaat tacgaaaatt gtaaaaaaat attagcatat actaatgaaa
    19021 atttattacg attttttatc aatatcttac acaatcgtat tatataatat tatcttttca
    19081 atatatttta taaactaata tattttacaa attgttgagt aatattttat gatataaatc
    19141 agaagaggca cttctataat agaaagtgct caactatgaa taagattaat aatatatttg
    19201 ccttagatat atagactttt ataaatatta aagattaatc aaatctgatg tttgaaactt
    19261 tatcccaatt aatcttcctt gaatagtctt ctggatgtga taatctaact atatgagttg
    19321 aattatcata gctgtaataa attgtagtag taccatcaac tggattcttt ttgtatcctt
    19381 gatacacagc actatttggt actttctttt caacaaagct atatgcagat gaagtatcaa
    19441 tagtttctat tttattagga aatataaaca tataaaaagc tactactata aaaatacata
    19501 tgcatgtaat actataccat ttaatccatt tcataaaatt cctcctactt taccaaaata
    19561 tactattatt atttccatat atttataata tttatgcata cgataaaatt tttatatccc
    19621 taactatata attgtagaaa ctttgattat atatattttt taatcttaat aatatatttt
    19681 tataaattaa taaattttta agattttatt aaaagatttt taaaacttac agtttaatat
    19741 aaagatagta cttataaaac taaaaacata aatttgaaag gggacaaaat aaaatgatat
    19801 ggacatttta ttcatttatt tgcgttatat taccatgctt aatataccaa atagtcgtta
    19861 taaaacgaaa aaatttgaaa gttgaaaaga atgtaatgat acatttagta tgggtatata
    19921 tttttttatt atatatctat ctagcactta gtaaagctgg aattggtagc atatgggata
    19981 taggaaggta tagtgggctt tttagaattg atgaaataaa tctaatacct tttgactcag
    20041 ttggcatctt aacatatatt ttaaatataa ttatgtttat gcctttagga tttttactac
    20101 ctttaatttg gaaaaatttt agaaatatta tcaatgtttc attaactgga ttaggttttt
    20161 cattagcaat tgaactttgt caattgttta acttaagagc tacagatatt gatgatttaa
    20221 tgatgaacac attaggtgct gttttaggat attttatatg ggtaggtgta aataatttat
    20281 ttaatcttat aaagaaaaaa gatattttcc catctatata taaaaatatt attcaagatg
    20341 agattgctat tacaattgat gatgacataa gcaaaaaaat tacctctctt tacaaaaatg
    20401 aagctattat atatttaata cttgctgttt taggagaatt tttattgttt aattggtcca
    20461 ttatacctta ttaaataatt tattgataaa ataagtgtac ttcgatattt acaaatatgt
    20521 aaagccctct ttcatactac aaaagaaagt gggctttagt tattaaatta aaatgcacac
    20581 tcactattta gctggcatct gaaatatttt attaacattg tatctgactt tatttgatgt
    20641 tatataatca tattttgttc cattttcaat gaagttttgt atattgtcca acacttgtat
    20701 agctcttgta ttattttcat aatctcctat ttttacagta tcaattttac tttcaaatac
    20761 tgcataaact tgactaccat ctattttaat ttggtttatc tgcattaaat tagttttatc
    20821 ttgacttcta attattatca tatcaattcc tccatttact taattcattt taatttctaa
    20881 taaataatat tttataattg atttatagat tatttaaatt tttaaactta gtattttatt
    20941 ttttaatacg attatttata tcaattacat ctctaataaa aaattttctt aaagaatact
    21001 tttttgataa tactttgttt tatttgtaga ttgcattttt gaccattata actaaattaa
    21061 ataatctaat gtattaaaac ataaaattat ctatgctact gatttatttt atacatttgg
    21121 taattttact tgcaaaaaat tttgtacata ttgtttatat ctcaattaaa ggttttcaaa
    21181 actttctatg tatttattaa ttaattcagt ttcttatttc aacataccac ctctcatcaa
    21241 attaccattt gtataattca tattatacat atacaaatgg taattttcaa tatattttat
    21301 tattttaacc tttttttttt atatttttgg taattttatt ttacttttta tcaaaataac
    21361 ttataatttc ggtaaggagt gatgtacata tggaaagttt aggagataga atagcaaatc
    21421 tacgaaaaga attagatata aatcaaaaag aacttgctac taaagtcggt ataactgagg
    21481 ctagcttgtc acgttatgaa aataatttaa gagaacctaa aagtgaaata atagttagat
    21541 tagcaaaagc attagaaaca tcaacagatt atttattagg cgtaaatgat aatacaaaaa
    21601 taagcaaaga agataaatta atcatagaga acttatcagt aagtgaaaaa acaaaaaagc
    21661 tcttagaaaa aatatattct cttgaaaaag aagatagaga agctatagaa aaaatgattg
    21721 ataatgccta tttaaaaaga ttccttaaag aagagaatta attctcttct ttttctttat
    21781 acaaaatctc aagtaataat tcataaaaag taatatcttc actcaataaa tgttctaatt
    21841 tcattcctat atcttcaatt ttttcttttt ttgtaacagt agtgtttgac ttttccacat
    21901 ataccatccc ccaacaaact tacgttctta atgttagtca gaaattccca acaaattttt
    21961 aataaagttt atgtaattgt attttgattt tataaaatat attttgatta tccaaaattt
    22021 ccctagataa ttatcttaat tatataataa tacttttatt ctacagttgc aataaaaaac
    22081 tcgtaataat aacaaaaaaa tctattattg tagaatcttg tatgtttttt
//
LOCUS       DAEHWO010000066        21942 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEHWO010000066 DAEHWO010000000
VERSION     DAEHWO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21942
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.066"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="KNP54_002859"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="KNP54_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBF0893731.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="KNP54_002860"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="KNP54_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBF0893732.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="KNP54_002861"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="KNP54_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBF0893733.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="KNP54_002862"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="KNP54_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBF0893734.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="KNP54_002863"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="KNP54_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBF0893735.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="KNP54_002864"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="KNP54_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBF0893736.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="KNP54_002865"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="KNP54_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBF0893737.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="KNP54_002866"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="KNP54_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBF0893738.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="KNP54_002867"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="KNP54_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBF0893739.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="KNP54_002868"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="KNP54_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBF0893740.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="KNP54_002869"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="KNP54_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBF0893741.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="KNP54_002870"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="KNP54_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBF0893742.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="KNP54_002871"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="KNP54_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBF0893743.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="KNP54_002872"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="KNP54_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBF0893744.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="KNP54_002873"
     CDS             6989..7174
                     /locus_tag="KNP54_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBF0893745.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="KNP54_002874"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="KNP54_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBF0893746.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="KNP54_002875"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="KNP54_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBF0893747.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="KNP54_002876"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="KNP54_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBF0893748.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="KNP54_002877"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="KNP54_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBF0893749.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="KNP54_002878"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="KNP54_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBF0893750.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="KNP54_002879"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="KNP54_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBF0893751.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="KNP54_002880"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="KNP54_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBF0893752.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="KNP54_002881"
     CDS             11117..11767
                     /locus_tag="KNP54_002881"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBF0893753.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="KNP54_002882"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="KNP54_002882"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBF0893754.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="KNP54_002883"
     CDS             12536..12805
                     /locus_tag="KNP54_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBF0893755.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="KNP54_002884"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="KNP54_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBF0893756.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="KNP54_002885"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="KNP54_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBF0893757.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="KNP54_002886"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="KNP54_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBF0893758.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="KNP54_002887"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="KNP54_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBF0893759.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="KNP54_002888"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="KNP54_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBF0893760.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="KNP54_002889"
     CDS             14901..15848
                     /locus_tag="KNP54_002889"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBF0893761.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="KNP54_002890"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="KNP54_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBF0893762.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="KNP54_002891"
     CDS             16330..17163
                     /locus_tag="KNP54_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBF0893763.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="KNP54_002892"
     CDS             17151..18017
                     /locus_tag="KNP54_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBF0893764.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="KNP54_002893"
     CDS             18011..18814
                     /locus_tag="KNP54_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBF0893765.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="KNP54_002894"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="KNP54_002894"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBF0893766.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="KNP54_002895"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="KNP54_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBF0893767.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="KNP54_002896"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="KNP54_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBF0893768.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21008..21760
                     /gene="cwlD"
                     /locus_tag="KNP54_002897"
     CDS             21008..21760
                     /gene="cwlD"
                     /locus_tag="KNP54_002897"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBF0893769.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8816 a         2563 c         4494 g         6069 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaaagagggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgagaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaatcgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctactttat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgag
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc tagatgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tgcttctatc aatagagagg tagtacatgg
    12001 tatcccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatgttaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagacat accttcatta atagttaagg ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagcgaaga ctatagatat ggtaagtttg ttatagagcc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtattaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccta ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga cgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatatttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 atatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtattta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagagcttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattgatata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gcagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tatagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga ctatttaata aaaaacatat gctaataaca tttaaatttt atttttataa
    20761 tattgtaatt taaaagttta tataaggtta tatattttaa gatattattt aacaatataa
    20821 attctgaata tacgttatca aaatttataa tataaactaa gtataattta ttgtatagta
    20881 ttgaatgtta gataaacata gtgaattaaa tagggacaga aatataatat cattacataa
    20941 taatatatta ataccaataa ataaagatat atcaatatta aaaaaattta aatgtttgta
    21001 ctaatatatg gaatattata gtgtttttat aagtatacat atacagggtg atgttgtgag
    21061 aaagtacata aaacatataa tttttagttt tgcaatgata tgtctagtag tagtatccat
    21121 atttgaaatt aaaaatattt ctgaagatgt tatcaagtat atgccagtaa caaacaaaac
    21181 tataatttta gatgctggtc atggaggcat tgatccaggt gcattaaata aggataagag
    21241 tacatctgaa aaggatatta acctagcaat aacacttaag cttagagagc ttatagaatc
    21301 aagtggtggc cttgtaatat taactcgaga agatgacagt agcctttata aagaagaaaa
    21361 taataaaact acaagacaaa aatataatga gaatttgaaa aatagaaaag aaataatatc
    21421 taattctaat gccaatatgt ttgtctctat acatcttaat gcatttgaac aatcaaaata
    21481 ctatggagct caaacttttt atcctaaaga caaacaagac agtaaagaat tatcgaagtg
    21541 tattcaagaa gaacttaaaa gagtagtaga taagacaaac aacagagaag tcaaaccaag
    21601 ggatgatata tatcttttga aagaaaataa tattccatca gtactgatag aatgtggttt
    21661 tttatcaaat gaaaaagagt gtaaactctt aactgatgaa acatatcaag aaaaaatagc
    21721 atgggcaatc tacataggaa tacaaaaata tttaagttga aataactata aaaataggtc
    21781 taaatatgta aatagcttgt attaaagcag ttaaaatgca ttaatatagg ctatttttat
    21841 tttgacaaaa aaatatttaa aataaaagtt aaaaagttgt tgacttagaa taatatagat
    21901 gatattatat atgagtgccc aaaaggagca ccaaaataag ac
//
LOCUS       DAEHWO010000067        21807 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEHWO010000067 DAEHWO010000000
VERSION     DAEHWO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.067"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            128..1021
                     /locus_tag="KNP54_002898"
     CDS             128..1021
                     /locus_tag="KNP54_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBF0893770.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            1199..2023
                     /locus_tag="KNP54_002899"
     CDS             1199..2023
                     /locus_tag="KNP54_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0893771.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            2122..2730
                     /locus_tag="KNP54_002900"
     CDS             2122..2730
                     /locus_tag="KNP54_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0893772.1"
                     /translation="MEKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            2834..3010
                     /locus_tag="KNP54_002901"
     CDS             2834..3010
                     /locus_tag="KNP54_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893773.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            4276..5028
                     /locus_tag="KNP54_002902"
     CDS             4276..5028
                     /locus_tag="KNP54_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893774.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            5018..7129
                     /locus_tag="KNP54_002903"
     CDS             5018..7129
                     /locus_tag="KNP54_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893775.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            7513..8223
                     /locus_tag="KNP54_002904"
     CDS             7513..8223
                     /locus_tag="KNP54_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893776.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
     gene            8746..10083
                     /locus_tag="KNP54_002905"
     CDS             8746..10083
                     /locus_tag="KNP54_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBF0893777.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPINILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
     gene            complement(10419..10988)
                     /locus_tag="KNP54_002906"
     CDS             complement(10419..10988)
                     /locus_tag="KNP54_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBF0893778.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVEGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            11358..11963
                     /locus_tag="KNP54_002907"
     CDS             11358..11963
                     /locus_tag="KNP54_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea carboxylase-associated family protein"
                     /protein_id="HBF0893779.1"
                     /translation="MTNWNLWRTLNMEYIINPCSGIKIKITRGQKIEIVDIEGGQVVD
                     FFAEMKDDSTEFISPGVTIDCNESLRLQVGNLIYSNKYRPMFKILYDDVREHDLLHPC
                     CRPEMYDFFYHNGENHPNCFDNINRTLGTSHQIIHPINLFMYTKVNTDGSIEVCEPLS
                     KANDKIILEALENMTLGIAACSVSESSCNSRKCTSIKILVD"
     gene            complement(12642..13544)
                     /locus_tag="KNP54_002908"
     CDS             complement(12642..13544)
                     /locus_tag="KNP54_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBF0893780.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHKYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            complement(13671..13790)
                     /locus_tag="KNP54_002909"
                     /pseudo
     CDS             complement(13671..13790)
                     /locus_tag="KNP54_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(14336..14998)
                     /locus_tag="KNP54_002910"
                     /pseudo
     CDS             complement(14336..14998)
                     /locus_tag="KNP54_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(15158..15694)
                     /locus_tag="KNP54_002911"
     CDS             complement(15158..15694)
                     /locus_tag="KNP54_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBF0893781.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(15767..16180)
                     /locus_tag="KNP54_002912"
     CDS             complement(15767..16180)
                     /locus_tag="KNP54_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBF0893782.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            16646..17200
                     /locus_tag="KNP54_002913"
     CDS             16646..17200
                     /locus_tag="KNP54_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBF0893783.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEDTI
                     SGMQGTISDMQGSISSMNGTISDMQGSISSMDGTINSMQDSITDMQVEIKEVNSRLDN
                     MEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINRNTLDTVIKHTSSLVKDTSDIK
                     NDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(17446..17601)
                     /locus_tag="KNP54_002914"
     CDS             complement(17446..17601)
                     /locus_tag="KNP54_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893784.1"
                     /translation="MVKFNQSLKVSKEKIITLKQEDINGKMKTRFYPFISDKGMCFNQ
                     RWTFILG"
     gene            complement(17808..17987)
                     /locus_tag="KNP54_002915"
     CDS             complement(17808..17987)
                     /locus_tag="KNP54_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBF0893785.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(18213..18746)
                     /locus_tag="KNP54_002916"
     CDS             complement(18213..18746)
                     /locus_tag="KNP54_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBF0893786.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            19063..19413
                     /locus_tag="KNP54_002917"
                     /pseudo
     CDS             19063..19413
                     /locus_tag="KNP54_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20494..21066)
                     /locus_tag="KNP54_002918"
     CDS             complement(20494..21066)
                     /locus_tag="KNP54_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBF0893787.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(21128..21391)
                     /locus_tag="KNP54_002919"
     CDS             complement(21128..21391)
                     /locus_tag="KNP54_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBF0893788.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(21391..21612)
                     /locus_tag="KNP54_002920"
     CDS             complement(21391..21612)
                     /locus_tag="KNP54_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBF0893789.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         7857 a         3334 c         2686 g         7930 t
ORIGIN      
        1 aaatataaaa aataggatat tattataggc aataactaac atcaagcgat aacttaatac
       61 atataaaaat aaataaacaa ttaataaaaa ttaaaacttc attataaaac ggaaggatag
      121 tgaaaaaatg caactatata acaccccctt taatacaaac aaacacttaa tctatttctt
      181 tacatttact ctagtattga actggatatt cagtcttaca cctgcgttgc tcggaattac
      241 aaatacaata cttggagaaa tcatttttta tcttgcatat acatcaccag ctattgtagg
      301 tctatttttt atttctacaa tctatccaca aagtgcaaaa caagatttta tttatagata
      361 cctaagcttt aaagaaatcg gaataaaatg gatactatta acaatattat tttttgcttt
      421 aacttttatt acttcgttaa taatcggaaa ttactttaat gtaaaaactt ctgatataga
      481 ttggatacac atagcagtgt ttagaccttc taaaatagct tatatgctat tagcaagttt
      541 tatattgagt atacttagtc aagaagctgg atggagagga tatgccattg acaaattatt
      601 agttagattt ggatttatag gctcttcaat tattttaggg cttgtttgtg gaatctggta
      661 tctagggtcg tattttacac ctaatcaaat accatataat ttggcacaat actccctatt
      721 tgatgctttt ttatttatac caaacattgt acttttaaac tttataatta attttgtata
      781 tatcaataca agtagaagca ttttatcagc tggattagtt catatgatgt actatttttt
      841 caacattcaa ttacttctac actaccctat taaattatgt gtaatagctc aatatgtaca
      901 aataatattt ggtttaatat ttcttgtata tatgatttct tctaataaat ttaaacagaa
      961 ggtaaattct gaaattgaac agataaagtc ggatgatttt gaatttgagt tagactggta
     1021 attttaatat gaattataaa ttaagataat ctatgatttg atacgattac tacttaaata
     1081 taatttactc tctataattt attgcaacat ctggaaaata attgtatttc cacaaacgct
     1141 tgaagtatat aaaaacaaaa tatatactga ttataagtga aaaggaggtc atattttcat
     1201 gtttaaaata ggagaggttt caaaactaac acaaatttct attcgtatgt tgcgttatta
     1261 tgatgaactt ggtattttaa aacctgcaaa aacagacaaa tatacaggtc atagattata
     1321 ctcagttgaa cagatttcaa tattacaaag aattgtatta ttgagagatt caaaatttag
     1381 cgttgcagaa atagcaaata tcgtacataa ttggaatgat gaatttgtaa ttaaggaatt
     1441 gaatagaaaa aagaatgaaa tacaaaagga aataaagcag gaacaacaaa gaataaataa
     1501 aattgataaa tttatagaag ctataaactg tgataaagat gaaattcatt acaatgttgt
     1561 ctttaaaaag attccaagtt ataaaatcat atcacttaga gagataattc cagactacca
     1621 atctgaaggt atactctggg aaaagctatc taaatttatc aaagaagaac atatagaagt
     1681 atcacgtcaa tccaacaata acatagcttt ttaccatgat gaagaagtca aagataatgg
     1741 tgtagatatt gaagttggaa tggttgtaaa gaagattgga aagaacaaat ctggatttat
     1801 atatcgtgag acagaagaaa ttgatatgat ggcatgtact atggtttatg gtccatatga
     1861 aaatatagct ggtgcatatg aatcgttctg ttattggtta gataaaaata gtgattatca
     1921 aatatcaggt ataaatagac aaatcggaca taaaggtgaa cataatgaaa taaatcctga
     1981 aaattatctt acagaaattc aaatccccct tataaaagtc taatagatta gtacttaaat
     2041 acttaagtac taatcaccca ttgacatccc aaaattttca tgatagtatc taaacgtgta
     2101 ttaaacatgt ttaatttttt tatggagaaa cttttaaggg gaaaaattat gaaagcagat
     2161 tcaacaaagg aacaattaat taatgccaca atccagttac tatcttcaca tagagatgtt
     2221 tcaagcatta cggctagaga aattgtagct aaagcaaatg tcaatttagc tatgattaat
     2281 tattatttta aatctaaaga ggagttaatt aatatttcta ttaaaaaatt tttaaagcgt
     2341 catatggatg aatataaggc tacacatgat actaaaaatt tagcacctaa acagcaatta
     2401 agggaaatac taattgcatt ttttgatttt ataggtgaac atagtcaatt tataaagatt
     2461 tctgtaccct atatattgat acaggaagaa attgtttatc catttgagat actaccttta
     2521 attaaggctc actatgaaaa tcagaataac aaaaaaactg aagctgaata cagaactatt
     2581 gcgtatcaaa taacttcatt tattcagttg ctttttcttc gttctaatgc ttttttcaag
     2641 tatagtggta ttgatattct taatattgaa cagagaaatg gtttaataga ttttcaatta
     2701 gatttattat tggtagatat tacaaaataa tactatatta attttttatg tacatttttt
     2761 tattttatgg taacgtttga aaatattctc attgactaaa aatacttgca ttaaataagg
     2821 gggaggaatt ttaatgtttt ttacatttat aggagtaata tcagcaattt tattgttgtg
     2881 tacaattata tgtggtttat ggataaaact taataatcgt aataatgact ctaattctca
     2941 ctttactttt tcaatacttt caattgcttt ttcactgtta attgtggtgg cctttttagt
     3001 aagaaattaa tgtctttgtt atgctgaggt ttattattat agatttttat tattgcatga
     3061 tttttactat attatagtat ttttattata ttacagggtc ttatttatta tagtgttttg
     3121 ttgttacagc attttattat attacagagt cctatttatt ataggatttt tattatattg
     3181 taaaatctta tttattatag gattttgtta tattacagac ttttattata ttgaaatctc
     3241 ttatttattg cagtgtttct attatattgc aaactcttat ttattatggt gttttgttat
     3301 tgcaacattt ctattatatt gtaaagtctt atttattaca gttctttatt atactacaga
     3361 cctttattat tacagcattt ctattacatt gtaaagtctt atttattaca gttctttatt
     3421 acactacaga cttttattat tacaatctct tatttattac agttctttgc tatactacag
     3481 acctttatta ttacagcatt tctattacat tgcaaagtct tatttattac agttctttat
     3541 tatactacag acttttatta ttacagcatt tctattacat tgcaaagtct tatttattac
     3601 agttctttat tatactacaa acctttatta ttacaacatt ttattatttt aacttcttta
     3661 ctataatata gtaatatttt aatatctcaa aatcatatca atcacttttc agcatagtct
     3721 aaaatacttc cactttctaa aattatctat catacctata ctaataatac tttttaacct
     3781 ttttattata catttcaatt gtttctaaca acctatttat ttccaaaact ccaatatatt
     3841 ttctcaatta cattgtgtta atagccccta aatcctttca aattatttac aatacattcc
     3901 attaaataat cttactgctc tataattctt tttttctttt taaccctact atacattatt
     3961 tacatcattt ttttcaatac aacattcgtt attctataac ctttttactt ttactatata
     4021 cttcttttct aattacacct tcaatgttcc acatcatatt actttagcac aacaattaat
     4081 acctaaaaat aaccctctaa atcctccaat aatataatca atttaactat aataataacc
     4141 tctcacacta tccaaacaat atattttcaa acattacaaa aaaacatcca actattacaa
     4201 tatagctcat atccctcctc ccctttcaaa tgctatcatt gacttacaag ataaatgaaa
     4261 gtgaggatga tatatatgct taaagtaaac caattatgta aatcatataa aacaggcagt
     4321 aaaacatatc ctgtattaaa aaatatttct tttgaaatca acaaaggaga atttgtcgca
     4381 atcatgggtt catcaggaag tggaaaaact actcttttaa attgtatttc atgttttatc
     4441 ccaattgata atggggaaat aattcttgga aataataata taagaaattt aaaagaaaag
     4501 gaactttcag aagttagaaa tcaacaacta ggatttgtat tccaagactt catgctattt
     4561 gatggtctta gtgtctttga aaatatatgt gttccacaaa ttatcaaagg tagtcaagtc
     4621 ttacaaatgg aaaaccgtgc aattaatcta tgtgagctat ttggtattga acatatcaga
     4681 aaaaaatacc ctgccgaaat atctggtgga gaaaaacagc gtacagcagt agcaagagca
     4741 ctcatgaaca acccagattt aatattagca gatgaaccaa ctggtaacct tgatagtaag
     4801 tcttgtcgta cagtcattga atcattttta aaagcaaagc aagaattaga tgctactata
     4861 ctcatggtta cacacgatag ctttgcagca agcttctgtg accgagttat tgtgcttaaa
     4921 gatggaataa tttataaaga agttgtaaaa tcaaattcaa gacataaatt cctagatgaa
     4981 ttactagaag ttttaaaaga aatgggaggc gctcaagatg acaattaata aattatacag
     5041 taaacttcga gcctataatt ggaagaacta tacaacttta ttcttttgta taatactttc
     5101 tgtggtatta gtaacttcat atgctctaat ttattttagc ccaacaatac aaaacatact
     5161 tccaactggt ggagatagca gaaaacaggc tacaatgata ttctcagttg ctatattagg
     5221 atgcgctgtc tttactacat acgcttcttc cctcttttta aaatttaaaa gcaaggaaat
     5281 tggtattttc atggctctag gaacagataa gaagaaatta aaaaaacttc tattttcaga
     5341 gatattgtta atttcaatag tatgctgttt tttaggtctt atattaagta ttcctgtatc
     5401 ttttggtata tggaaaatat ttcaattagt gattattgat accagagaaa tgacatatca
     5461 ttttggaact caaggattca tatatggatt tatatttagt gtatttgtga cattatgcat
     5521 atttatactt tctgtaaaat ttattaatcg tacaaatata attgatatat taaatgacca
     5581 gagaatatct gaaccaatac aggatgtaaa ggactggtat ggtatattag gtataatttt
     5641 tattatactc ggtatttttc taggatatct cgtaccttca ctaactataa acaaattaaa
     5701 ttataaacta ccatctatat ggagctttac ttatctactc tctcttattg gaatatatat
     5761 gattatgaca tacatagttg tacatgctaa aagaggaaaa catccagaga aatactataa
     5821 aaacatcata tcaactagca tgatgagatt tatgggaaga caaacagtaa aaaacatgtg
     5881 tgttatttca tttttgattg caggagcatt atttgctgta ttctatgttc ctaatatggt
     5941 tacaggtatc tatgatactc ttaaaaataa ccctatagat tatactttta cctacaatca
     6001 aagagataaa caggtatcaa aaaaagatat tgaacaatta gcagataaac acaatataaa
     6061 aattcaaaac tatatggaaa ttccttctat agaattaatt gttgatggtg tagaatcaat
     6121 atatcataaa gatggaacta tcgaaaaggt atatatgaaa aaaagctcct atgatatgtt
     6181 ctttaattcc aaagattttt ccaagctaat tggcaaacca ataactataa aaaatggtga
     6241 atatcttgct gttgtaaata aaggaaatga aaatcaagat tataaatata ccaaatttat
     6301 atcaagccca gtcacagaaa aagaaatccc ctttagatat gctggaaaaa taatatttaa
     6361 tggttctttt tttcaaaata gaagtatgaa cgcctatgtc cttaatgagg aggattataa
     6421 atcatttact aaagatttat ccataaaaaa ttacaataat tctatactat ttaatgtaga
     6481 taaagatacc tatgcttttg ccaatgactt aaagaaagaa attataaaaa gaacatctaa
     6541 ggaaatgggc atgttcagtg gttatgatga atacgtaaaa aaacgttatg aatcaactgg
     6601 aagaaaatat tttatggatg aagaatatcc aagtggtgaa ggtcatttaa aactagaccc
     6661 aaacaacaat cagttgtatc ttaattggaa atactatcct aactttaaaa ttttacaaag
     6721 ccaagatatg ataaaaaaca tggcagtctt cttaatgtta ttcatatatg tggcaatcat
     6781 atgttttaca gcagtaggaa tcattgcata tacaaggggt gttactatag ctataaatca
     6841 caagcaggtc tttatggatt taaatcgatt aggagcaaac aatgattata taaagttctg
     6901 tattagaaat caattaaaga aagtattttc ataccctctt attgcaggaa gttttttaat
     6961 ttatctgttt aattttatga ttatgttaaa taatgatggt agaatcgtca atagtgaggt
     7021 caatgctctt ttgataaact taggttttat agggatttgt ggggtttata tgtaccttat
     7081 atatctatta acttataaga aattcaaaaa aattattggt attttataat aaaaaaggtt
     7141 attagatttt taaagtaata aaatcattgg tgttttataa taaaaaaggt tattagattt
     7201 ttaaagtaat aaaatcattg gtgttttata ataagaaagg ttattagatt tttaaagtaa
     7261 taaaatcatt actttttata ataataaaag catttgtatt ttataataag aaagattgtt
     7321 agatttttta ataagaaaat cattagcact tcagaataag tttaatagaa tagttttaag
     7381 tgtaagtata ctaatataaa aaattttatt ttgctatctg gatataattg ttatttcatt
     7441 ttatatatct aggtagcaaa atatattata tacttaacta tataaatata aaacttgaaa
     7501 ggagataaaa aattgacttc gatttgtatt tgtgatgatg aaaaacaaca aagaaacatg
     7561 ctgaataaaa tcattacaag agaaatggat ttgtggggct acccctacca aataaaagaa
     7621 tattcaaatg gagaaagtct agtatacaat ctagaacacg aaaattatta catagatatt
     7681 atttttttag atattgaact tggaaaaagt aatggcgttg acatagcaaa aactatacga
     7741 aaacattcaa aagatactat aatcatcttt gtcacaggtt tttctgacta tgtatttcat
     7801 ggatatgatg taggagcttt gaactacatc ttaaaacctt ataaaactga aaaaatatgt
     7861 aaagtattaa aagaagcact aaaaaaatta gaacaatgga aagaaaactt tattacagtt
     7921 cagattggaa ctaatctttg taaaattaat acaaaagata tcctctactt taaaagtgag
     7981 ctaagaaaat taactgtagt tacctttgat aaaacattag aatactacgg aaaattaaat
     8041 gatatggaaa ctgttcttcc ctctaatttt atacgtacgc atcaaaggta tattgtcaat
     8101 ctaaaccatg tagatagtat aactcaaact tatgccaaag ttcagaatga aaaaattcct
     8161 ataagccgta aaaaatatca agaggttgta ggaaaattta caaggtatat gttagaatct
     8221 taatttttga agttcaatct ctagaatttt atttttgaaa cttaactttt taaagcttag
     8281 tttttagagt tttgtttttt caaatttaat tttttgaagc ttaatttcta gaatttcaat
     8341 ctttcaaaat ttaatttttt gaagcttagt ttttagagtt tttttcaaac ttaatttttt
     8401 aaagctcagt ttctagaatt tcaatctttc aaaatttaat tttttgaagc ttagttttta
     8461 gagttttttc aaacttaatt ttttaaagct cagtttctag aatttcaatc tttcaaaatt
     8521 caattttttg aagcttagtt tttagagttt ttttcaaatt taattttttg aaacttaatt
     8581 tttaaaattt caatctttta aaactcaatt ttttgaagct taatttctag aattttattt
     8641 ttcaaaatca attctttgaa atctaatttc cagaatttta atttttaaga tttaattttt
     8701 taaaacttag tttccagaat cttaattaat agaaaggtat attaaatggg cacttattct
     8761 ttaatctcta caagcataaa ttttattcta atattaatca atattttcat agcctttttt
     8821 ctttataagt tgacttccta ttttatagac tttaggaatc attggatttt caaaatcata
     8881 ttgattttgg gctactctat tattagtcaa atgataatat ggctttccga ccccataaat
     8941 attttgttta cactattcgg atattttata ctacttataa tatgtagcaa aagcaaatta
     9001 attcctataa tatcagttgt catgatactt tatcctatta taattgggct taattttctt
     9061 tttataaaca accctatata tgaggaactt atacactcaa aagagtatat tttaatactt
     9121 tcaatagtcc agataatttc tgctctaatt aaattattat tttggttttt aatacatatt
     9181 ttcctaaaga atagattggt caatataaaa caatacttat caaataaaat atggattttt
     9241 attgatatgg tatgtatatc ttcattttta tcaatattaa ttgctattat tctgccacct
     9301 actaatttaa tccctatggg tagtaataag aatattatct taggcaactt accttatggc
     9361 acttatctaa tcatcttgtc agcaattctg gcaaatatcg gtgtgatact tcttttacag
     9421 ccattgattg aaaatgtaaa gatgaagata gaaaaacaag caaatcacct aaaagaaaaa
     9481 tactataact tactagaaaa tcaacaaatt caaatacgca aaatgcgaca tgatatgaat
     9541 aatcactttc aaatgattga atcgtattta gaaattgaag atattgctgg agctaaaaag
     9601 tattttaatc agttaaaaat aggtataggt actcttagtg gaaaacaatt ttgcaaaaac
     9661 caagctctta actcaatttt aaatcttcgt catacaagtt tagaagaaaa tggtgttgat
     9721 gtgcacttta atatagatat agacaatcac ttgggtatag aacctataga tttatgtact
     9781 attttttcaa attctttaga taacgctata gaagcatctt tgaaaattcc tgatttgtca
     9841 aatagaaaag tggtattaaa ggcacgttgt gagaaggagt attttagcta tttattgaca
     9901 aacaacaagg taaatcctat caatagaaaa caagaactat ttatttcaga taaaaaagat
     9961 agtaattctc acggatatgg tattgagaat attagagaaa ttgttaataa gtacaatgga
    10021 aaattggata tttcttatac tgagagtgaa ttttctttat ttctttatat tagattattt
    10081 tagtctaaaa ttagattatc ttatataata caaattagat tgtttgatac tatgtaaaat
    10141 tataataact tataattaaa tatttacaca tatattcatt aacttaaaat ttaatcaaat
    10201 gtgatatttt atttacctta gtaaaaatgt gtgtgtctca aaataaactt tttagttgat
    10261 gaggcactct tttttacatg aaatcaaata tatttttatc ctttcaacaa tgaaaaatgg
    10321 atttatctct ccattttgaa acaagccctt tttctattaa ttactttctt aaaaaatata
    10381 atacgatata taagataaat atctaattgt acctatttct aattatatct attagaatac
    10441 aacacctttg ccttttcagt aaactcccta acaaaatcta gtttactatc tgtataagca
    10501 tcacgattat gctcatactt cttccaaagg tccaacttaa gtttttcata ctcctttgca
    10561 acatctgggt ggtcaattaa gtaatctcta aaaaacaact catcattatc acctacatac
    10621 cttatatgca aatgaaaaac tcgttcttca aacccctcta ctgtataccc tttattaagt
    10681 gaaagcctac tactgctctc agacatacaa atatatccat tcgactcaat caaatcttta
    10741 atatctttca tattataatc aggaattatc tcaatcagta tgtcaacaat gggcttggca
    10801 taaatcgtac tcacagaagt acttccaata tgacttattc taacaatttt ttgcattggc
    10861 aatattccag ttagtctata ttgttcttct ttaaaccaat ttttccaaca ttctttgtga
    10921 gtagtcaaaa atataggaaa caagttccat aactcctcta aagtcatatc ttccaacttc
    10981 tttttcatta gttacctcct tttaaatttg tactttatat tttttctttt tcaaatttac
    11041 ttagttaata tttaacttta ttttttatca aatcattttt ctaattatgt aaatttttct
    11101 aaatttagtt tttaatgtat tataacagat ttttaccctt cttacacttt tgtatctatt
    11161 taaatattag aacatttttt cttacttcta aatacagtaa gattgcttaa ataccaaata
    11221 ggagcaaaaa aactctgtaa tctaaaaaaa actacaacat ctttatgaga attaaaaaat
    11281 gatagactat gttatcaaca ttaagaaaca gatagaaaag aaacagagta tgtgctaaaa
    11341 tgggaacata gaacagaatg acaaattgga atttatggag gacattaaat atggagtata
    11401 taatcaatcc ttgtagtggt ataaaaatta aaataactag agggcagaaa attgaaattg
    11461 tggatattga aggaggacag gtcgttgatt tttttgcaga aatgaaagat gattcaactg
    11521 aatttatatc tccaggtgtt acaattgatt gtaatgagtc attaagatta caagttggga
    11581 atttaatata ttctaataag tatagaccta tgtttaaaat tttatatgat gatgtaaggg
    11641 aacatgactt gctacatcca tgttgtagac ctgagatgta cgatttcttt tatcacaatg
    11701 gagaaaatca tccaaactgt tttgataata ttaatcgcac acttggaact tcccatcaaa
    11761 ttattcaccc cattaatttg tttatgtaca caaaagtcaa tacagatggg agtattgaag
    11821 tatgtgaacc tttatcaaaa gccaatgaca aaattattct tgaagcattg gaaaacatga
    11881 ctttagggat tgctgcatgc agtgtttcag aaagttcttg taatagcaga aaatgtactt
    11941 ctattaagat tttggttgat tgacaaattt catttatcga aaaaatatca aaattaaaaa
    12001 atgacgtcaa aggcgcaaaa gggtaaccac ttgcgctctc aattcattat ggtttgttac
    12061 gtatttatgg gtaaaaatcc cttgattcta tgatgttttt cagacacaat tacaaatgag
    12121 taaggatttt atactcatac tctaaaaaat agcattttat tgcgtaacag aacgaaaaaa
    12181 cagtgtgtac ctttttcttg caatacacac tgtattcata gccactctag ctgttaactg
    12241 ttaattatct cataataccc ttactggtat tcatctaatc ttaacccctt ttaattattt
    12301 tcatttataa ataaattcta ttcttcccaa aatatcgtaa ttaaaatata ttaattaaaa
    12361 tatcccaata agaatatctg aaaaatcttc tacctatttt ttcaaacctt ttattcccat
    12421 tcctcataca atagtgcaac ttttagcaca gtataaatat accattagtc catataatct
    12481 cattaacaaa tatatacaat tattttcttc aaactctttt atatctaaga tatcacattt
    12541 tcattttctt atattaattc cttaactctc tttcaaatta ccaatttttt aatcaaatct
    12601 tcattaaata ttctatcatt attaaacatt catcattatc cctaaaaaat atgtgccgta
    12661 tgttctttac acaaattttc catcttatca tacacagcac cactatctct ctcatctgtc
    12721 atagtcacaa ttacatcact tggtctaaga attgtcttac ctctaggaat aatttcttct
    12781 ccacctcttt gaattgctac caaaagacaa ttttcaggcc actgtacatc ctgaattgcc
    12841 ttgttcgcaa caggagagcc aaacataaca gagaactggt ctagtatctt ttcgcccctc
    12901 tctttatgta caggttctcc attcttttca agtaacctct caagaagact ttcataaata
    12961 ggtttagact tcataagtgt agccacaata tatgccacaa ttgaaattac tgatagtgaa
    13021 agcatttgac taacagaacc tgtcatttca aaaattaata tgataccagt caaaggggca
    13081 cgcacaatag ctgtaaaata tcctgccata gccaaaagca caaagttatt tacataatcg
    13141 ggattcattc caaaaacttt aacacctacc ataccaaata ttccacctat aaatgctcct
    13201 aaaacaagca atggaaaaaa tattccccct ggtgcacctg acccaaaact aacagccgaa
    13261 aatataaaac gtataacaaa aatcaaaaca accattccaa aaatatattt atgacttgta
    13321 agttcttcaa ctaaattgtg tccactcccc agaacatcag gcataacaag cccaagaata
    13381 ccagccatta taaatggaat caacagtttt ccaaacgtac caattttagg aatcttcttg
    13441 tataaagact gcacatatag agtaaaccag ttgtaaaatg cccccataac tccaagaata
    13501 acacctaaaa tcactattaa tccataataa tcttgtggca acacatttcc aatctgaacc
    13561 tcccatgact aaagtcacag ggttcctgct tcatagaatt ttgcatacta aaatatgtct
    13621 tactaattct ccacaggcta tccccgtagt tcctacggtt cttacataag ttatttattt
    13681 tgaattgtta ttagtcttaa tccttctttt aatatattta tacttgcatt tatatctcta
    13741 tcgtgagttt cattacaact aggacaaatc cattctctta taataatgtt aacaaatgta
    13801 attatttaaa acaattattt agaaggtttt atatttaatt ttaaataaca tatttaagaa
    13861 ccgtaagtct taacttttat catttttgag gttgtcgttc acataagttc gctactacct
    13921 atgcagttct cttatgaact tcttacactt tcatgcaagc acagactata tcttatcctt
    13981 cggcattatc cgttaaggtc tacccacttc cactaccaat agcttgtagt gtacttccct
    14041 caagaggaat agtcgttgaa gtttctccta ttcggagttt acctgctgat tgcccatttt
    14101 aaagtactta gggtttaacc ttataccatc taaccaattt tttctacttt cgtaactttc
    14161 acacttaggt ttatttcatc cttatgtttt agtttggtta gctttagggg tttccagcaa
    14221 ttcaagtagt attggatagg ttctatccta tctctacata taggtttccc tatatgctga
    14281 ctattttagc tactaactca tgactaaagt cacaagtgtt cgtagctatt ttttaatcaa
    14341 actggaatac agactccatt cctaggaaat tggctgaaat atagtctgct gtcaaagatg
    14401 ctgtcatcac agaaattaaa acagatactg aaaagttttt atggacttct tcaagtgaaa
    14461 acataacacc cgctagtggt gcatgaaagg ctgctgataa tccagcactt gccccacagg
    14521 ttaacaggaa tttttcctct gtcttccctc ggtcaagagc tctagaaata cctttacctg
    14581 ccatagcacc aagctgaatg gaaggacctt cccttcccaa agcaagacca cccatgagtg
    14641 ataagaatcc tccaataaat tttgttggca acactcgcca ccatacttgt tttattttcc
    14701 ctgtcatttc cccctcaagc tgagggatac cacttccaga aatcattggc tcccagtcca
    14761 ccaactttga tacaatccac gcaagtactg caagtactgc aaaccaagct attattttta
    14821 ttgtagaacc ttctacaaat tttaaaattt ggctaagcca agtaccagcc tgccctaaaa
    14881 gtatcctgta taaaagcaca atcaaaccag ccacagcccc aaccataagt ccttcaccaa
    14941 tcaaaattac ctgaaagtgc tctgcccgtt tgataatatg agatgtatcc tttttcatac
    15001 tattcctcct tcatccaata attctacaca atctgaatct ccaatgacta aagtcatgag
    15061 tgtgtacaga tattttttaa tcaacaaaaa tagattttta cttactaaat ataagaaaat
    15121 aattgctcaa tttctcaata aatgtgaatt tattctttta ggtatttatt ctccacagtc
    15181 gtgcttcttc cagcaaaata tttattaatt cttgctttct ctgtgtatag attttacgat
    15241 tgtcctcaaa ctgtaatgct aatttttgtt tatgactatc atagagtttt gctttgtctg
    15301 taaaagtatt tagataatct cgaaaattga tataattatt ccatgcaaca ctattccatt
    15361 caacaacatg aatatggtga gtacgagtat ttttctcaaa atctcccata gcaaaaagta
    15421 attgttttgg tacatcctga cctcgaaaaa cgattccaca ttgctctaac ctttcgaggt
    15481 ataatttagc ttcctctaaa gaagcaacac ctacaacaat atcaataata ggctttgcgc
    15541 taatactggg aatagaagtg cttccaatgt gttgaatatc aatagcagtc ttatcccata
    15601 tactttttaa taatataatg acatcttttg cacttttatc ccatatcatc tgatgttcca
    15661 ataatttaac cataccacat tttaaaccta tcactatata ccacctcaat ataatccacc
    15721 tttatatata ttacaatttt ttctatcttg ataaatagtg atttagctat ttcacttttt
    15781 cttgacactc gctacattcc ctatcatgaa tagatataat tcctccacat ttagaacaag
    15841 tatatctctc cttctgcttt tgcataaact tctctaaacc gtactgctga acaaatttac
    15901 tattttccat aaggcttgct tgatatctct tgttataact tttttcaaga ttttttatga
    15961 gtttacaagg aaaattgaaa cattcaaaac aataaaacaa ccctttttga cagacacaat
    16021 cctttatttt gcacttacgg cagtgttctg gctttcctgt atcgccgttc aaacaaccag
    16081 cacatggctt tttgtgataa caatgcttat agcaaaccat acaattcatt ccacaaggag
    16141 caaacataat cgtatcaata ctctcttttg gcattttcat aacattttac tcctttcaaa
    16201 aatccaattt gtcgaattgt tatatattca tattgtaaca taaaaaatag ctaaaaaatt
    16261 catgcacttt cattgccaat aaattttcaa ggaaatatga aagtttaaaa ctaagaataa
    16321 aaagagataa aaaggaagct actaatcaaa atattcaaac acaagtaatc aatataaata
    16381 acttaaggta tatttaaaag tatatgatat taccagcagt tttaaataca aatataacca
    16441 cacatgcctc aaaaacactt attacagtat cttagaaact tagacaatac ataagattca
    16501 ttaataaaaa agttctcaat atagatatat ttaaccatgt tttgaatagt agataatcat
    16561 atgattaaaa attaaatatg acatagcgtt tgtggaatat aacacctaaa ttatgttata
    16621 ataataaagc aggagtgtga tagtgatgga tgaaaaaata ttagagttat tacaggaaat
    16681 gcaaggtaat attagtaata tgcaaggtag tatcagtggt atcgaaggca ctattagtga
    16741 tatgcaaagc aatattaatg gtatcgaaga cactattagt ggcatgcaag gcactattag
    16801 cgatatgcaa ggcagtatca gtagtatgaa tggcactatt agcgatatgc aaggcagtat
    16861 cagtagtatg gatggcacta ttaatagtat gcaagacagt attactgata tgcaagttga
    16921 aattaaagaa gtcaatagta ggttagacaa tatggaacct gatattaaag acttaaaaac
    16981 tggacaagtt gaaactagta gtagacttga tactattcag agtgatgtta cagaaattaa
    17041 gtcagatgta aaaattaaca gaaatacatt agatacagtg attaaacata cctcttcatt
    17101 agtaaaagat acatcagata ttaaaaatga tttaaataat atagagatag tcacatctaa
    17161 gaattcgaat gatattgcta aattaaaatc agttaaataa tatactatag taaaaaatac
    17221 ctgaaaattt cacatacttc tttaaagtta taccaaattt tatacagaaa tactgattat
    17281 ccgacaacac actttactta taaataattt attaaaaaaa tactcatttt atcctaaaat
    17341 taacacgact aaatgagtct tgatataata ataaaaaata agggagattg aacactaaaa
    17401 agttgtgtat ctcccttata ttctataata tagttatata atttttcagc ctaaaataaa
    17461 agtccatctt tgattaaaac acatcccctt atcacttata aaaggataaa atcttgtttt
    17521 catttttcca tttatatctt cttgcttaag agtaataatt ttttcttttg atactttaag
    17581 tgattggtta aatttaacca aacgactaag ttttgttcaa catctatttt tcatattttc
    17641 caatacttaa tctatttttt ataaataatt cttttatttc taactcactt acatttttta
    17701 cataaaacga agcatataaa tttcaacctt atcttgtatg gttcttaata cttaatgagt
    17761 agcttaagta tcaatcatta taaatttttc ccttacattt aacactctta ccatttccaa
    17821 aatatacaaa atatattttg aacatttgta caatgatgaa atacaataca tgaaaataca
    17881 atatcataac tgttgtctaa aaatagaagt tcttcaacat aacctttcac aaaaaacata
    17941 ttatctaagt attttttgtc tgctccttgt tttcctgttt gtagcatata aattactgca
    18001 tctaaacata taactactca cacgaaaaaa gaaaataaac ttccaaaata caagctctaa
    18061 aaactacctc taaagttgta taatgtttac taggaataag gttgtataac atatagttta
    18121 aataatcatt ttttaaaatt gcaagttatt gctttcaaaa ttagatgttt ttatatcaaa
    18181 taaatgatta agaatttcta aatttaatgg ctttataatg cactcccttt ctttgggata
    18241 aaataatgtt gcacagatac tttttctaaa gataacaatt ttatttttct atcaattcca
    18301 ccagcatacc cagtcaaact cccatttgtt cctacaacac gatgacatgg aataataata
    18361 gagattccat tatgccctac tgcaccaccg attgcttgtg ctgacatttt agatattcct
    18421 ttttgttgag caactttata tgcaatttct ccataagtga ttgttttacc atatggtatt
    18481 tgttgtaaaa ttttccacac tgtagtctga aaaggagtac ctaccatatg gagtgatggt
    18541 gtaaaattgg gttcttttcc cgaaaaataa atatctaacc atttctttgt ctgctcgaaa
    18601 attggcaatt ctttttcttg atgttcttgg tcaagattat aagcataata cttttgattc
    18661 tcaaaccaaa gaccagttaa cccaatatta tctgatgcta aaagaatatt tccaattgga
    18721 ctatggtaat agctaatata ttgcatacaa ttcctcctta tattctgaaa acttcactca
    18781 aatcattaga cacttctttt ctatctacca ttatgtaaaa acatactaat ataatttcct
    18841 tctaactaca ctttcgttat aatatctatc ctcatatcat attagtttta tatttacctg
    18901 catctgttca tccttttttc cctttccctt tgatgaatat aaaattcata catttaagct
    18961 tcctactgta ttaactttta tagaagtgta tattataatt ttatcactaa ataggccaaa
    19021 aaaatatcga tatagcatca agtaatatca taatactttc aaatgggaaa agtaagaata
    19081 ggctgtaaaa aagaaaagta tttttatgtt agaaatccag taaaatcatt agtagataga
    19141 ataacagaaa acgaacaatt tgctatttat cattttacac ataaatataa ttgacgcaat
    19201 aaagtgtttt ctattctaca acgattaata aggttagaaa aaagtaaaaa tgaactgtat
    19261 atgtatgaag cattagtttc tgtttctttc ctttggctta ttatgataaa aaatattgtt
    19321 ttgctaccaa taaaacacaa aaatataatt aatatccata tgcaaaaaat tttacgttat
    19381 attgaaaaat actattgttt tacattatat tgaagggtac tattgtgaaa acttaatttt
    19441 ggagtactat caagcagtgg taatatcaat aaatcagagt gctccagatg atttgaacta
    19501 agtttaaata ctatacctta taaatatttt actgagtttt gtttattaaa agcaactcaa
    19561 tttctaaaag gcacaaatga gctaataagt gacattgcta taaaagttgt ttttcatcaa
    19621 ataatctatt ttagtaaatg ttttaaagaa aaaacgggat attctccaaa agtgtacaga
    19681 aatataaaaa aagagatatg attttttatt tcttttgatt atccaaagag taaataaaaa
    19741 atattgtaaa aaacttacta acaacggcaa tgctttgaac tatggtaata ctttgaactt
    19801 ttgattggac tttttttgct aaaataatat atttaaatag caaagtaatc tgtttaatca
    19861 ataaaaaata agagataaaa gaaatcaact aaaactttta cctcttattt tgatagttta
    19921 tcagagctaa tatttacact ctttttattt ttgatacttc attaaaaatg atgcttactc
    19981 tccattcact tttaattctt cattaaaaat gatgcttatt ctccattcac ttttaattct
    20041 tcattaaaaa tgatgcttac tctccattcg cttttaattc ttcattaaaa atgatgctta
    20101 ttctccattc acttttaatt cttcattaaa aatgatgctt actctccatt cgcttttaat
    20161 tcttcattag aactatgctt actctccatt cacttttaat tcttcattaa aaatgatgct
    20221 tactctctgt tcacttttaa ttcttcatta aaaatgatgc ttattctcca ttcactttta
    20281 attcttcatt aaaaatgatg cttattctcc attcactttt gattcttcat taaaaatgat
    20341 gcttattctc cattcacttt taattcttca ttaaaaatga tgcttattct ccattcactt
    20401 ttgattcttc attaaaaatg atgcttattc tctgttcact tttaattctt tattaaaact
    20461 gatgcttatt ctccattcac tttcaattct tcattaaaac tgatgcttgc actctgtaaa
    20521 ctcataaaca tccattaatg cttcaccaaa tctttgatag tgaactactt ccctctcacc
    20581 caaaaatctc aatatatctt tcaaatcagg gtcatcagtt aaatttatta attgatagta
    20641 cgtagccaat gctttttgtt cagcagccat atcctcatgt aaatcagtta ccgaatcgcc
    20701 aaagacatta atataacttg tagtaaagtt tactccatta gaatctactg gctgaagacc
    20761 atgtccaaaa ttagcataat tactaccaag tccagcagcc ttaagctctt ctggagtaca
    20821 attgcctatt aattgatata acactgaaga aattatctca acatgagcca tttcctctgt
    20881 acctatatca gttaaaagtg cacgagattt tccagttggc atagtatatc tttgttgaag
    20941 atatctagtt gcagctgcca actcaccatt aggtcctccc aactgagtca tgatatattt
    21001 tgccattcta gggtctgctt gtcttatgtt aactggatgt tccagtgttt tttgataaat
    21061 ccacatatta tcttactcct ccttaatata tatttaataa taaatctaat tttaaagttt
    21121 aataatttta tttataaaat gatttgtccc atggccaagg ttcagatatc catgaccaag
    21181 gatattcact tgattcatat ccaaaattag ttaatgctcc atatttagat tcataatcac
    21241 acacagcttg tgtaaattta tcgcagtatc tgttgtatga atcaagagct ttcttatccc
    21301 ttggattgtt atctaaatat aaatttaatt ctatacaggc aaattgatat tctgaaattc
    21361 tctctaaaag ttctcttcta tttaatgaca ttagtacatg ttaccccctt ttttagctct
    21421 aactctattt ttaggatttg catatagcca atcattatag ttatttgact ctattaaatc
    21481 taattcagga aataaagtac ctctttttaa tgctgttttt ggattgtatg tgtcatcata
    21541 aatttgacga ttgatgtatg gtctagcaaa ttcacaacaa tagtcttgtt tatcctcttt
    21601 taaatatccc attaattatc ctccttaatt tttagaattt taaaatagca ttatttttaa
    21661 aaattgtata ctggttctat attataactg gtagttttaa taggtcttta ataagattaa
    21721 atgattaaat aagtatcttt ttttcttatt ttacctctaa aatttttcta attaatcttt
    21781 cataaatatc tattttaaat aaataat
//
LOCUS       DAEHWO010000068        21751 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEHWO010000068 DAEHWO010000000
VERSION     DAEHWO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.068"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(86..277)
                     /locus_tag="KNP54_002921"
     CDS             complement(86..277)
                     /locus_tag="KNP54_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBF0893790.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(425..667)
                     /locus_tag="KNP54_002922"
     CDS             complement(425..667)
                     /locus_tag="KNP54_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893791.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            879..2702
                     /gene="typA"
                     /locus_tag="KNP54_002923"
     CDS             879..2702
                     /gene="typA"
                     /locus_tag="KNP54_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBF0893792.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(2792..3700)
                     /gene="trxB"
                     /locus_tag="KNP54_002924"
     CDS             complement(2792..3700)
                     /gene="trxB"
                     /locus_tag="KNP54_002924"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBF0893793.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCITSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    4502..4733
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4841..6322
                     /locus_tag="KNP54_002925"
     CDS             4841..6322
                     /locus_tag="KNP54_002925"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBF0893794.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            6332..7225
                     /locus_tag="KNP54_002926"
     CDS             6332..7225
                     /locus_tag="KNP54_002926"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBF0893795.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            7349..8410
                     /locus_tag="KNP54_002927"
     CDS             7349..8410
                     /locus_tag="KNP54_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBF0893796.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(8565..9077)
                     /locus_tag="KNP54_002928"
     CDS             complement(8565..9077)
                     /locus_tag="KNP54_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBF0893797.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            9597..10532
                     /locus_tag="KNP54_002929"
     CDS             9597..10532
                     /locus_tag="KNP54_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBF0893798.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(10624..12495)
                     /locus_tag="KNP54_002930"
     CDS             complement(10624..12495)
                     /locus_tag="KNP54_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBF0893799.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHILS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            12685..13611
                     /locus_tag="KNP54_002931"
     CDS             12685..13611
                     /locus_tag="KNP54_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBF0893800.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            13750..13896
                     /locus_tag="KNP54_002932"
     CDS             13750..13896
                     /locus_tag="KNP54_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893801.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(14001..14525)
                     /locus_tag="KNP54_002933"
     CDS             complement(14001..14525)
                     /locus_tag="KNP54_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0893802.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(14578..14802)
                     /locus_tag="KNP54_002934"
     CDS             complement(14578..14802)
                     /locus_tag="KNP54_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893803.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            14999..16123
                     /locus_tag="KNP54_002935"
     CDS             14999..16123
                     /locus_tag="KNP54_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBF0893804.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISTFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSDSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(16597..17421)
                     /locus_tag="KNP54_002936"
     CDS             complement(16597..17421)
                     /locus_tag="KNP54_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893805.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(17769..18824)
                     /gene="ispG"
                     /locus_tag="KNP54_002937"
                     /gene_synonym="gcpE"
     CDS             complement(17769..18824)
                     /gene="ispG"
                     /locus_tag="KNP54_002937"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBF0893806.1"
                     /translation="MSYERRKTREVSVGAVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(19007..20011)
                     /gene="rseP"
                     /locus_tag="KNP54_002938"
     CDS             complement(19007..20011)
                     /gene="rseP"
                     /locus_tag="KNP54_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBF0893807.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(20024..21178)
                     /locus_tag="KNP54_002939"
     CDS             complement(20024..21178)
                     /locus_tag="KNP54_002939"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBF0893808.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(21342..21545)
                     /locus_tag="KNP54_002940"
     CDS             complement(21342..21545)
                     /locus_tag="KNP54_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0893809.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         7492 a         3393 c         2618 g         8248 t
ORIGIN      
        1 taaatgtata tataaaaata gagcatctaa attgtttaat gcttatacaa tttagatgct
       61 ctatttatta tattttattt aaaatttatt ctttacatgc ttcaaaaaac tctgcttctg
      121 tttcctttat ttcaagctca ttgtctatta ttccaacagc ttctttttta aatgctctac
      181 actgacctat acaaccagtc tttacatttt cttctccaac caaagttttt agcttattta
      241 catccacatt tgaacagttt ggacatactc ttatcatatt taagttcctc ctaattaatg
      301 tctaattaat acttttatac ccaaatataa actttataaa agttttttta atataaatta
      361 ttaccatata taccatttat atcctattgc gagtattaca tattaatttt atatattatt
      421 aatactacat gtacggtggt atctgttgtt ttctcactat ttccaattcc ttaatttcta
      481 aagacttaat cacatttact ttatagtttt ctttagactt tatatacaaa acatcttcta
      541 tctttttacc ttcaataaat ttatgagacc acttaagaag ttcttcaaaa ttacaaactt
      601 cttcttttac aaaagtatca ctttcacttg caaaatattt aattattatt ttggttactt
      661 ccaacatata tcatccttta ctcttttatt aatcttttta tctattaagg ttattatttg
      721 tctaaaaaat ttttttaaac aaaataattt tcagatgcaa aactaacagt tttattcaat
      781 ttaaactata ttaatacaat ttaatatatt cctccttgta cctaataata tattgtgcta
      841 taattaataa gttattttaa tcgaagggag caacaaaaat gtcacaaaaa cataaaatta
      901 taaatatcgc agttatagcc cacgttgacg ctggaaaatc aacattggtt gatgctttcc
      961 tttctcaaag cggtgttttt agaaagaacg aagtagttaa agactgcgtt atggacagta
     1021 acgaccttga aaaagaaaga ggcataacta tatattcaaa aaactgtgca ataaactatg
     1081 aagattacaa aataaacata gttgatactc caggacacag tgacttttct tctgaagttg
     1141 aacgtgttat gaaaactgtt gacacagtta ttctattagt tgatgctagt gaaggcccaa
     1201 tgcctcaaac tagattcgtt ttacaaaaat ctttagagtt cggtttaaaa ccaatattat
     1261 ttataaacaa gattgataaa aaagaccaga gagcggaaga agtagttaat gaagttttcg
     1321 atttatttgt agacttaaat gcaacagatg agcaatgcga atttcctata atatatggta
     1381 ttgctaaaca aggtattgct aaacttgaaa tggatgatga tagtgaagac ctttctcctc
     1441 tatttaaaac tattgtaaat cacgttgaag cttatcctaa ttacgataat gaacctctac
     1501 agttccaaat atcagctctt gcatatgatg attatgtagg tagacttggt ataggtagaa
     1561 tttacaaagg tactcttaaa aacaatacac aagttgctat atgtagagaa gattctgttg
     1621 tatctaaagg aaaagtatca aaactttctg tgtatgaagg tttaaaacaa gttgaagttg
     1681 atgaagctac tagtggagaa atagttgtta tagctggtat tcctgatata tctataggtg
     1741 aaactatatg cgatttagat agtccactac ctatggaaat gataaaaata gaagagccta
     1801 ctctttctat gaacttctta gtaaacgact ctccattcgt tggaaaaagt ggaaaattcg
     1861 ttacaactag acatttgaaa gatagacttg aaaaggaact tgaagtaaat gttggtctta
     1921 aagttgaacc tcttgatact actgatggat acaaagtttc tggacgtgga gagcttcact
     1981 tatctatact acttgaaaat atgagacgtg aaggttatga agttggtgtt tctaaacctg
     2041 aagttttaat gcataaagaa gatggaaaat taatggaacc aatagaaaga gttgttgtaa
     2101 actgtcctga agtttactct ggtactatta taaatgaatt aaacatgaga aaaggtatga
     2161 tggagtctat gtcaatagaa ggagactatg taaaaataga gttcttagca cctactcgtg
     2221 gtcttttagg atatcgaagt gaatttataa acgctactcg tggagaaggt actttagttc
     2281 gttcatttga aaaatttgaa gaatttaaag gagaaatacc ttcaagagga aatggtgttt
     2341 taatagcaca aggacctggt gttactatgg ggtattctct taatgcctta agtgatagag
     2401 ctgtaatgtt tgtagaccct ggtgtagaag tttacgaagg tatgataatt ggtatgaatt
     2461 ccagaaaaga tgatatggta gtcaaccctt gtaaaaacaa gaaaatgagt aacgtacgtg
     2521 cttctggttc agatgatgct ataaaattat ctcctcctag aatatttact cttgaagaag
     2581 cactagagtt tatagaagat gatgaattag ttgaaattac acctgattct ataagactta
     2641 gaaaaagatt cttaaatgaa catgatagat taagatataa caaatctaga caaggtaaat
     2701 aaaacgtaca tttacctcta attaacaaaa tagccatata gtactgaaaa attatttcag
     2761 tttatatggc tatttttatt tgaaatttat attattcaac atttatataa ttagctgctt
     2821 gaacggctgc aatagctcca tctgatgctg ctgttattat ttgacgtaaa aacttagttc
     2881 tactatctcc tgctacatat acaccttcta ctgatgttat acaagactca tctgaaatta
     2941 tatatccacc ttcatccaaa tcaagaacat tttcaaacat tttattatta ggtttaagac
     3001 ctatagcaat aaaaatacca ctaacatcta tagttctttt ttcttcagtc tttaagtttt
     3061 ttacttctat tttcgataca gtcttttctc cttctatttt ttctacacca tgactgtaaa
     3121 gtatctcaat attctctctt gctttcacag atttctccaa cacttcttca cctctaaaac
     3181 tatctcttct gtgaattaaa tacacttttg tacaattatt agctaaaaat aaagcatctt
     3241 ctagtgcagt atttcctcca cctactatag caacttcttt atctttaaaa aaggctccat
     3301 cacatgttgc acagtaagat actcctctac ctgtaaattc ttgttcccct gcacaaccta
     3361 atttacgtct ttcaactcca tttgcaagaa taacagcctt tgctttatgt tcacctgaag
     3421 aagtttttac aacctttact tttccctcta aatttatctc ttcaacctca tcaaactgaa
     3481 tatcaacacc ttgagcaact gcttgattgt atatattatt agaaaattct accccagaaa
     3541 tcttttgaac tgctggataa ttttctacct cagaggtact tgcaacttga cctccataaa
     3601 tatttttttc aaatactgta acgcttaacc ctgctctcat agcataaatt gctgaagtta
     3661 aacctgctgg tccagcacca attacaatga tatctaccat aacgtttacc tctctttata
     3721 ttattatttc ttatatatta ttctcatcat tcttatactt tactattatt atccatatat
     3781 actataaaca aaacattatt ttttattaat taactttatt ttacatatat ataaaaaaac
     3841 tgcaaataaa aattaacttt tatttacagt tctcacttat ttatataatt caaaacctta
     3901 ttggttatca tttacagtgt cttctaatat attgctttct gatatatatg atagaattga
     3961 aagtccatac ataaccaaaa ctaatgctgc tgttataagt actattccca tatttaatac
     4021 ctccttttgt ttacagtata ctattattat gtgaaatatt tatgaattta atttgaatat
     4081 atatgtaatt tcacactaac aatttcttca aattaaacat tattaactat atacttttgt
     4141 tgaaccaatt atgattaata gtttaaatat tagcactatt tacttatatt tatatgatat
     4201 accatataat tacatttttc aaattaaagt tttgtaaact ttttttgtaa tatagtgtag
     4261 tataaaattg taatattaca gatatttaat agttatcttt taattacttt cattaaaaac
     4321 agcttcatca ctatgaaaat ctaggttttt aaacttttaa aaaggttaaa aaaatatttt
     4381 tctaatactc aatttgatta caattttttt acaatttaaa aaatattttt tccaaatttt
     4441 tatattaata cttgactttg tctgttttat aaactagaat aattaataat attaagaata
     4501 ttgaaaggca ttgattagga agagtaaatc tgaatcgatt accagagaag gaaactacta
     4561 gctgaaatgt ttccctaatt agaaggattg aaaactacct aggagcttct atccgaagtt
     4621 atcttaatga ttttagtagg aatagacgtt tttattactt gcgttaaagt atcaagtgga
     4681 ttttttaaaa tcaatttggg tggaaccgcg ggaaacagat tctcgtccct tttttaggga
     4741 tgagggtctt tttttattac ctaaattcag tttttaaaat attctgtatc taatttaatt
     4801 agctaattaa aaatttaaaa tatatggagg attataaaaa atgtattatt caagtacgag
     4861 aggcaccgaa gaaaaagtaa ctgcatcaca agcaataata aaaggaatat caaatgatgg
     4921 tggtctttat gttccaagtg aatttcccaa tgtaaaaaat gaacttataa atttagtaaa
     4981 tttaacgtat tctcagatag cattttttgt acttagtaaa tttttatgtg attttactga
     5041 agatgaaatt aaaaattgta tagaaaatgc atatgatgaa aagtttgatt gtagtagtat
     5101 agctccatta aataaagtaa atgatactta tttcttagaa ctatatcacg gtccaacttt
     5161 agcatttaaa gatatggcac ttactataat gcctcatctt cttaaaacat ctataaagaa
     5221 agataattta gagaaagatg ttgtgattct tactgctaca tctggagata caggtaaagc
     5281 tgcacttgag ggatttaaag atatagataa aataaagata attgtattct tcccagaaga
     5341 tggtgtaagc ccagtacaaa aacttcaaat gaaaactcaa actggaaaaa atacatatgt
     5401 agttggtata aaaggaaatt ttgatgatgc acaatcaggt gtaaagaaga ttttttctga
     5461 taaagaattt aatcaaaaac tattggataa taattatata ttatcttctg caaattcaat
     5521 taatatagga agacttcttc cacaagttgc atactatttt tattcatata tgaaattagt
     5581 tagcaatagt gatataaatt taaatgataa aataaatttt gttgtcccaa ctggtaattt
     5641 tggtaatatt ctagctggat attatgctaa acaaatgggt cttccaataa acaaattaat
     5701 atgtgcatca aatgataata atgttcttta tgatttcttt aaaactggtg tatatgataa
     5761 aaatagaaca ttgaaattaa ctacttctcc ttctatggat atattaattt caagtaattt
     5821 agaacgatta ctgtttgaaa tatcaaatag aaatactgat attgtaaata agcttttatc
     5881 agaccttagt gataaaggag tctacaaaat aagtgatgat atggaaaaaa atttagcctc
     5941 attctatgga gaatattcaa atgaagaaga agttaaaagc acgataaaca atgtgtttaa
     6001 aaattataat tatttgatag atactcatac tgctgttgca tacaattgtt atgaaaaata
     6061 taaaaaagaa acttctgata acacaaaaac tgttattgta agtactgcaa gtccattcaa
     6121 gttttctgaa gatgttctaa agtctataga ttgtgatttt aaagaccttg atgactttgc
     6181 tataattgat agattatcaa gtatttctaa aatagatatt ccaaaaccta ttaaaaatct
     6241 taaaaatgca gaaatactac ataaagatat ttatgaaaaa gatgaattaa aactagctat
     6301 aaaaaaattc ttaaaggtat aggtgattat tatgttagag attatagttc ctgcaacaag
     6361 tgctaatata ggtccaggat ttgattgtct tggaattgcg ttaaatatat acaataaatt
     6421 ttatgttgaa gaaattgaaa gtggtcttga aatagaaggt tgtgaagatg cttacaaaaa
     6481 cgaaaacaac ttagtttata catctatgaa gtactttttt gatagagtta aaccagaaaa
     6541 aatacctgct ggtatcaaaa taaaaatcca aagtgaagta cctatatgta gaggtcttgg
     6601 cagtagtgcc tcttgtatag tagctggagt tatagctgca aatgctctat caggtgctaa
     6661 tttagataaa aatcaattac taaatatagc ttcagaaata gaaggtcacc cagataatgt
     6721 tgctcctgct attttaggaa atatgattgt atctgttact gataatgaga atatacatta
     6781 tgatattata aaaattcctg aagaacttaa attttgtgca atgataccta attttaagtt
     6841 atcaacagaa aaagctagag gtgttttacc aaaggaaata ccatattctg atggggtatt
     6901 caatgttagt agagttgctt tactaatatc tgccttacta aacaaaaact ttgacctact
     6961 taaagtagct tgtcaagaca aattgcatca agattataga ggaactctaa ttgagaacta
     7021 caatgatatt gttgaaaaat ctgaacaatt aaatagtatt ggagtatttt taagtggagc
     7081 tggacctact ataatgtctt taataaaaga aaatgatgat agttttgtgg ataatatgaa
     7141 aaattaccta caaaaactaa aatctgattg ggaaataaaa gagttatgtt gcgattctaa
     7201 tggagctgtt ttaaatataa tataattatc gtcttctata caaaatataa ctactctttt
     7261 attataattt gtagtataat aattaggact aggtaataat attaagtatt ataatctagt
     7321 tctttaaaca tgtttacatt gaggagggat tatcataaaa gagttaataa ttagagattt
     7381 agttgcaaaa gttcctataa ttcaaggtgg aatgggcgtt ggtatatcta ggtcatcact
     7441 agctggtgca gttgctaagc ttggtggtgt tggtgtaatt tctggagttc aaattggata
     7501 tgatgaggaa gattttgaaa ctaatactat aaatgcaaat ttaagagcta taaaaaaaca
     7561 tatttctaag gccaaagaaa tctcaaatgg tggtattatt ggtattaatt ttatggtagc
     7621 tatgaaagaa tatgaaacat acgtaaagga agctgttaaa gctggtgtag accttataat
     7681 atctggagct ggattaccta ataagctacc atcattagta aagggaagta atgtaaaaat
     7741 agcacccata gtttcaactg caaaagctgc taatgtaatt ttaaaaatgt gggatagaaa
     7801 agagaaaact actgctgact taatagttgt tgaaggtcca aaagctggtg gtcaccttgg
     7861 atactctaac gaggaacttg ataacataga ttctatagac tatgataagg aatttgttga
     7921 aattttaaag gttgcaaata cttatggaga aaaatttggt agaaacatac cagtagttgc
     7981 tgctggtggt ataacttcta gtagtgatgt taaaaaatat atagatatgg gtgcaagtgg
     8041 tgtacaagtt ggtacaagat ttgttgctac ttacgaatgt gatgcccatg agaactttaa
     8101 aatggcatac ataaatgcta gtgaagaaga tgttcatata gttaaaagtc ctgtaggtct
     8161 tcctggacgc gccataagaa acaaatttat agaagaagtt aaaataaatc gtccagaaat
     8221 aaagaagtgc tataattgtt tgattccttg taatccaaaa gaaactcctt actgtatttc
     8281 tcaagctcta atcaatgcag ttaaaggaga tgttgaaaat tcacttttat tttgtggaaa
     8341 tgatgcctat aaaattgata aattaagtac tgttgaagat gttatcaatg aattgatttc
     8401 tgaattataa tttaaagaaa actaaattaa aattttatca agctaaggag tttaaatacg
     8461 ttatttatta atctttataa acatatttat gtccttagct tttttgtgtc aatttccttt
     8521 tatggaaatt ttaatttaat tagagatagt attaaccttt ataactaatc ttcttttaca
     8581 agtacattgg ttatttcagc tatatataaa gtatgataat ctttttgtgg ataccatctt
     8641 ccatctatac cttcagcaat aaaacattga ggttcaagtt tctgactata catttttttg
     8701 catataatag ccattttaga ttctttaaaa taaggtgtat catttaagtg ttctatatta
     8761 aatccaatct gtgatatctt atcctcttct ctaccagata cctttccaca atatgaaagc
     8821 tctttacgaa aatcttcatc aaaaaatgta agagaaaatt tatctgtatt atctataaat
     8881 tccttagtat aacgctgtgg tcttattact acaaaagcaa catcttttcc ccacataact
     8941 ccaagccctc cccagctagc agtcattgta ttcactttac cttcattttc tgctgttata
     9001 agtgtccaat ctttacctat caatccaaat ggattatttt taatctcttc tgccaaaatc
     9061 tctttaaaat cactcatatc tctaataacc tctcattctc ttatatttat attcctttta
     9121 ttttcgtgat aaattataaa tgaagtctag ttttgaaaat aaaatacttt tttaaatata
     9181 ttattgcaaa taagtaaata tatatatact ctcttatttt ttaatatatt taataatttc
     9241 actcagaata tatatattct ttactcaaat taaatataac ttatatactt tatgtgtaaa
     9301 ttatggtaaa aatattattt aatcaaatca aaacttgatt tatatacctg gaaaaggtat
     9361 tatattaaag agtgcttaaa atacgcattt cataaatagc tatatataaa ataataaata
     9421 aggagagtga tgggcaatgg atactagtcc gttgcggaga gaatttttta cattttcatc
     9481 acttaataat atctaaaatc aaaactaata catatattca gttatataaa ttagttaatt
     9541 aatagatact attaaatgat gagatttata taaaactgaa taaaggatgt gttgccatga
     9601 taagatatta caaaactata gattcaaaat tagagaaact tagttttttt gaagatggct
     9661 gttggataaa tcttgttgaa cctaatcata gtgaaatcaa cgaaatttct aatttattaa
     9721 atatagatgt agaaagcata gaatctgcac tagatgaaga agaacgctca agaatagatg
     9781 ttgaagacaa tcatactctt atacttatag atataccagt agacgaaagt gactctaatt
     9841 cttctcatta tactacaata cccttaggta ttatactaac tgaagaagct attgtaacag
     9901 tttgtgatgc acaaactaag attttaaatg actttatagt tggtcatatt aaagattttt
     9961 ttacgtttaa aaagactcgc tttttgcttc aaattcttca caaaaatgca gcttattact
    10021 tgcattactt aagaaaaata aataaaatga caatcataat agagcgagaa atttacaaat
    10081 caatgaaaaa caaagaattg gttcaattat tggaattaga aaaatctttg gtatacttct
    10141 ctacctcact aaaatctaat gaacttgttt taaacaaaat ggttagaact gctggtataa
    10201 agaagtatcc agatgatgaa gacctattag aagatgttat agttgaaaat agacaggctc
    10261 ttgatatggc taaaatatat ggagatatat tgagtagaat tatggatgct ttcagtgcaa
    10321 ttataagtaa taatcagaat aatgttatgc aaattttaac agtagttaca ctaattttct
    10381 caatacctac aataatatca ggattctttg gtatgaatgt catcaacatg ccattttcta
    10441 ataacccaaa cggattttgg ataatacttc ttattacctc tataatatgt atagtgatta
    10501 catttttcat gtcaagaaat aagctattat aaaatattaa taaaaaggcc attagaatta
    10561 attgatttac atttatccta atggctttta tatatttaaa tctatataat cttataatac
    10621 tttttaacta tcatgttctt catctataat catttcagtt tcaagccctt ctagcattga
    10681 atctaaactt tcttttatat ttagtatata aattggtaca tactcttctt catctattac
    10741 ctcttcttgc aacttaaatg gaggaattaa tacttcatca aagtctatat ttaaatttgg
    10801 aaagccttct actatctctt cacaattatc gtactcttca tttgctaaag aaatgtacat
    10861 atctaggctc tttttataat aaagacctgc aagcatatac tcacacttct tacttccata
    10921 tttaatacct tctttataat atttctcagc ttctgcgtca tcatttaatt ttaaataaat
    10981 ttgacctaaa ttatatattg attcaacaca accttgtgct ctagcctttt cataccaaaa
    11041 tttagaattt acataatctt tatagaacat atcataaatt aatcctacca tatgttgagc
    11101 atacacatta ttttcattgg caggtgtatc aaacatcatt ttagactctt ccaatttacc
    11161 ttctctaaaa taaattctac ctagatgtat acgagcattc atatggtttt tgctacttgc
    11221 catttcaaaa tactttctag cattttttgt atttcctaag ctctcatata tacaccccaa
    11281 tctataacta gacctcgtat ctccattttc agatgctttc ttataccaac ttattgcttc
    11341 ttcaatatta tttaaatctt catagatatt tcctaatttg atttgacaag atacattatt
    11401 tggaatcctc gaataatacg aaatcgcttt ttctatatct tgattctgat aatataaatc
    11461 ccctagattt tcaagggaac ttttgcatcc aacagctata gcatcctcat aatatttaat
    11521 agcattttca taatcttttt cttcaaaata tatacctgcc agattatttt ttgcttctgt
    11581 tatatcatct tcagcagcca ttttataata agtttttgcc ttctctatct cattttctct
    11641 attatataaa ttagcaagtc tatacttaga aagtatatga tttttttcta ttgctttctc
    11701 ataataataa attgcatctc ccagctcttc ttttctatca tatacatatg caagcctata
    11761 ctcagacttc acatcatctc tatcagcact ctttttataa tacttctctg catcttctaa
    11821 attatcattt atttccataa tcatacccaa gttaaagcaa cctttcatat gacctgactt
    11881 gtacaactgt ttatataaac ttactgttga tttattatct ttcttttttc catttaatat
    11941 tgctaaatta tattttgcat catcatctaa aagcacagaa ccttttttat agtattcata
    12001 tgcttcatca tctttctcca aaaaagtata taatacccct aaattaaaac aagctttacc
    12061 taaattcttg tctgctgctg tttttaacca tttttcacac cttacaaaat ctttcatttt
    12121 aaaatggcat acacctaaat tattttgtgc ttgtaaataa cctaaatttg ctatcttttc
    12181 ataccaatat atagcatatt catagccatc taacttatag tacatattac ctaaatcaaa
    12241 agcagcatct tcacttccac ttttatatgc catcgaatac cacttttctg cttctttaaa
    12301 ttgtttttta ctttcatata tatttcctaa agtatattga gattttacgt aattatccaa
    12361 tgcagcactc ttatacaact ctattgcgct ttccatctta cccatctttt caaggagggc
    12421 acccttagta tgtacgactt tcgggtcatt agatatattt tttatttttt ttatagaaaa
    12481 ttttgtattt ttcattattc gctacctacc cattttataa aatatattct ctcaaacatt
    12541 attatacatt ataatctaca attaatgcta taatattgaa tttttacctt ttgtcactat
    12601 attgtaacat taaattttaa attttataat cattagattt tattatgtaa ttggtatata
    12661 atgtatatat aggggggaca ttttatgaat ttcagcaata tttttatcca agttgcagtt
    12721 ttatttataa ttattttagt tggatatttt gtcagaaaat tcaacttatt agatgaccac
    12781 tgcacatcta agctttcaac tttgacaatg acagtttttt taccatcaat gataattagc
    12841 tccatgcaaa ttaactttga tagtaaaatg atacaaaaaa tactattgtt attatttaca
    12901 tctttgatta tgtatatagt ttcaattata attgcatttt tattgaaata cattttaaaa
    12961 tgtaatgata aaaaagattt gggaatatac cagtatatag ttgttttttc aaatgttgct
    13021 tttatgggtt atcctgtaat tgaagcagtt ttaggtcatg aagcaatatt ctatactgca
    13081 atattcaatt tgccttttaa cttattttct ttcactttag gaatttatct tttatctaaa
    13141 ggcagtacaa gtagaggttt ttcaataaaa tcacttataa gccctgctac aatagctatt
    13201 gttattggac tttttttatt tgtaacagga cttaggttac cccaatttat aaacgagcca
    13261 cttgagatgt tgggaagtat aactacacca atatccatga ttatcattgg aagcttactt
    13321 gctaattctt cagctctcga ttgttttgtc aacaaaaaat tatatatagt cacttttata
    13381 agattattgg tacttcctgt gattgtgtat tttattctaa aaggatggat aaatgataag
    13441 atgattttag ctataccagt agtaatttct tcaatgcctg ctgctgcaaa tactgctata
    13501 atggctaatc aatatgactc caatataaca ctagcttcac aatgtgtgtt ttttacaaca
    13561 ctattttcag ttatatctat accttttata agtattttac tcttatcttg atttattttt
    13621 ttatgtatta tataataaca tattcaataa attacaaata taaacatttt attgtagtat
    13681 attgatggaa ttttttccta gatatttgtc aataatatct atatgtatta tagaatagga
    13741 ggcttaaata tggatatgga tttactcttt aaaatagtat ttgctatagt tgctataggt
    13801 gtttctgtaa aaatcattaa aactgttgct agtttagctt ttaaaatagc gttgatattg
    13861 ctaataattt tatttgtata tagaatgttt ttgtaaacat ttaaaaataa gttttttaac
    13921 acaatagaga agtaaaatag attatcttta atgtaaattt tttattaaag acactctatt
    13981 ttacttctct attagcttct ttaaattaaa tttttattat atcttcccat aatataaaca
    14041 tcttcaaatt ttccatctct gattacagca tattttttag ttccctctat ttcaaaacct
    14101 agctttttat ataaatttaa tcccttttca ttatccacaa ttacttctaa tcctactcta
    14161 gttaacataa tccaattatc tgctatatct aaaagttgtt ccataagctt cttacctact
    14221 cctcttccct gataattctc tgcaacactt attcctattt ctgcgctatg tctcaatcgt
    14281 ggagaagaat ttacatgtaa cccagcaaaa cctattacat ctttttctcc attattatta
    14341 gtttcagcta caaacatata atcattttct cccaaagaag ctaacatagc ttcagtttta
    14401 tcgactctgt cactcattaa tgccaaagta tttctcataa cactgtatgt tcttctaatt
    14461 tcattaaaag cttgtgcatc ttctcttctt ataggtctta ttgttatatc tataggctta
    14521 ctcatattgg attccccctc aaacataatc tttattttta attaaaattt tacatcttta
    14581 ttttatactg ttcaaatcta tgtatgcttc tacctgaggt acatatatca tattatcttt
    14641 tatatgtgta cttccaaatt cttttaattc tgtaccttct ttatccttag ttattttata
    14701 tctaatggat tccatacctt caactacttc agcatgaaaa aacatacctt catattgttt
    14761 aaatctaaaa ttaaaattgt ctttagtaag ttttattatc atatttttat ctactcctta
    14821 tataattgat atttttctta ttattagttg tatatatact gcttattcat attaatatat
    14881 tataacttat catttattta gtataaagtt ataaatagat atatttatac ttattttaca
    14941 atctttcttc aattgatata taatatgttt atataaacta atgtatgtga ggtgaaatat
    15001 gagcaaaaaa acaaaatatt tttctttaat tctctttcct attgctttgc ttttaaattt
    15061 tatagccagt aaagttccaa atattgttga aaaatattac tcccaattca tagataaaat
    15121 aattgtacaa atattgagta aagtttctgg aattttccca ttttctctct atgagattac
    15181 aatgtacata atagttatat ctaccttctt atttttatgt tgtactttat ctacaatttt
    15241 taataagaaa aaaaaattaa acatatattt aaaaaattcc attttaaata tattatccat
    15301 tgtatcaata gtctactttc tttttgtagt gctttgggga ataaactata ataggattcc
    15361 actagaaacc acacttataa ataactataa tttaaaaaac aatacctcta tccaatcaaa
    15421 acaatatagt gttaaagagc ttactaaatt atataaattc cttgtaatta aagcaaatga
    15481 aactagaaaa ctcacattac aagataaaaa tggtattgta aaatctaata cagattataa
    15541 tggtgtcata aatagagctc aactaggata cgataatatc ttggatatat tacctggtgt
    15601 tagtgatagt tattctaagc ctaagtatat tatttcatca aatctaatgt gctatacagg
    15661 aataactggt atatactttc cttttacagg tgaggcaaat gtaaatatag caatacctga
    15721 cttatatatt ccttgtacag ttgaacatga aatggcacat caaaggggat ttgctagtga
    15781 agatgaagct aattttatag cgtatcttac ttctataaaa caccccaata ttgattttaa
    15841 ctattctgga tatattttag ctttaaatta tactgcttct gctttaagta aggttgatta
    15901 taatgcatat gttgatattt ctgctggcat ttcagattct gtccgtagag atttaaaaaa
    15961 tgaaagtgaa ttttggcaaa aatatgaagg taaaattaat gaaatttcta atgagtttaa
    16021 caattcttac ttaaaagcta atggcgttac tgaaggtact cagagttatg gtaaaatggt
    16081 tgatttattg ctaacttatt atgaattata tccatataac taaacactac aattcaaaat
    16141 tttattcata tacagctgat attaaatcag ctgttttcta tttaaataaa ttatttaact
    16201 tcaagcaatc ttatataatt tgatagtact tatactatct gtataacatt tcaattctaa
    16261 ctattttagt taaaacattt ctattatctt ttttaataaa tgttttaact aaaattttta
    16321 aaacataaaa cttccacatt atttcactat ctatataaaa atctaaaaat tcacatataa
    16381 aattacataa ctaaaaaatc ataaatttat agaaaacata tattcaaaat aaaaaagcat
    16441 gtatcaaaac ttgacacatg cttataatct tatgtatata tatcattttg tcacaataaa
    16501 aatttacttg taacactgat atttttaaac aaaatagtcc ttatttaatt aaattaacat
    16561 taattaaatt cgtactcatt ttgctatcat taaacattac ttatagtaat tttctaatac
    16621 actatttgaa acttccttcc cttgaaaact tttcaaccaa ttctcatatg ctgagttttt
    16681 ccatacacta ccatcattaa atgttacttg ttttacacaa gatataatgt actttacacc
    16741 atgctctcca gttgattgtt tccatttatc aaacaataga aaggcatcat tttgattctt
    16801 acctggtgct attgcatttt gctttgcata ttctttctcc atttgtttcc attctttcaa
    16861 ccaattttct acccatgcct tgccttgttg tttttcaaac atacttatta tatcctgtgg
    16921 tggtgattgt tgcatttttc tataagtatg tgaatatgat tttggagaca caggagatat
    16981 gcctgtaaca ataccatagt ctacaccagc tgggctaaat ccaacacttc ctacttcgcc
    17041 atctgctgcc acattttgag catcccaata tagctcaagt ggttttccat ttttatcata
    17101 tgctaagcat gtaatttcat aatccataat tgccttttca ctgctatttg ttaagcttat
    17161 aacattgcta ggccaatgat atggagtatc atcatactgt attttgctat tatttataaa
    17221 taatggaata ttctcattat aaacaagacc tttactactt tgaatatctg ataccttctt
    17281 tgtgacagta cttaccgtat ttgctaagta tacatttgtt ttttctgaat tggtcgtact
    17341 aagagaaaat gttgttgtcg ttccagtaat cagcaaagca acaactaaaa taggtaagct
    17401 agatattttt ttatatctca caattcttca cctctttttc tattaactta taataaaaca
    17461 atttaccaaa acattaaaat ctatgttaac ataatttacc aactgttcta gtaactatat
    17521 cctatcatag ttactatcaa gtttcaatac tattgatgga aattttcact atattaaatc
    17581 tttttttaat tttataaatt tacaatatga tttaactcat acatatatag tcaaattaga
    17641 atataagttt cttacattta atgaagttta taaaataaaa aatgactaga taattaaata
    17701 ctgtaaataa aaacttatta caaaagtatt taaaaatcta gtcatttaat atatatatga
    17761 attgtatact ataatttttc aatctcttct agcaactcat caactaattt gttaccatca
    17821 atcattctaa ctatttcacc ctttttaaat aaaagacctt cacctttacc cccagcaata
    17881 cctatatctg cttctctggc ttcaccaggt ccatttacag cacagcccat aattgcaaca
    17941 gtgatatttt tttccatact accaatcttt tcttcaacct catttacaac actaattaag
    18001 tctatattac atctaccaca tgtagggcat gatataactt taatcttatc atttaaaagt
    18061 cccaaacttc ttaaaatctg tttaccaaca ataacctctt caacagggtc gcctgttaaa
    18121 gatattctaa cagtatctcc aattccttta agaagaagtg ctcctacccc tatagaagac
    18181 tttattgttc ctttgtgaac acttccagat tctgtaattc caatatgaag aggataatca
    18241 actttttttg atattaattc atatgcatca acagttttat aaatatcgga tgattttaga
    18301 gatataacta tattatgaaa atctaagtct tcaagaatct taatatgtcc cattgcactt
    18361 tcaactaatg cttcagcagt tgcagagcca tactttttta aaagttcttt ctctaaagaa
    18421 cctccattaa ctccaattct aatttttaaa tttctttcct tgcatttctc aactaccatc
    18481 ttaactctct ctatacttcc aatattacca ggatttattc ttattccatc cacaccttgt
    18541 tctatagctt caagggctag cttataatcg aaatgtatat ctgcaataat tggtatattt
    18601 acactagact ttatctttgc tatattttta gcagctttaa tatcaggaac agcaactcta
    18661 actatatcac aaccagcttc ctctaatctc tttatttgag ctattgtagc atctgcatct
    18721 cttgtatcag tatttgtcat agattgtata cttataggat tttctcctcc tatttttaca
    18781 gctcctacac ttacttctct cgtctttctt ctctcgtaac tcatattcca cctctatata
    18841 ttattttata ttgaatctct ttaaatatta aaatattata acctacatgt atattataaa
    18901 ttaaaaagct atctagttaa ataagaataa atttcatata taaaaattaa tttattctta
    18961 tttaaaacta catagcctat tttcttaaaa tctctaaaaa actaaatcat tgaaataatc
    19021 ttagtatatc tttatatgtg ataaaaagca taaataacat taaagctcca aaaccaacaa
    19081 catttatcat gccttcttta tttgggtcga gttttttacc acctctaaca gcttctagta
    19141 acaacataag tattctccat ccatcaagtg ctggtattgg taatagattt actataccta
    19201 aatttaagct tatgacagct gctaaataca ctacatttat gatgcctgta cgagcagcat
    19261 ctgataccat accaataaca cctactggtc ctgctacagc attgccaatc cctcctggta
    19321 cacgtcctgt aatcatttga cctagaaatg ttagcatctg ttttgtcata tctacagtag
    19381 ttttacatgc atttactatt gaccctaaaa agtctttttc tctttgtggt tgaattccta
    19441 tttcatactt tccattgtta tttttaggtg ttacatttac aactttatca cttccatctc
    19501 tagttatact aagttttaat tctccaccag aagaagtgtt tattatattt gcaacttcat
    19561 cccaagtctt aacagaatta ccattaattt tatttatctt atctcctact tgaagcccta
    19621 cagcctgtgc aggagtatct ggcattatct ttcctaattt agtcgttgga gaacctatat
    19681 acaaaaatac tggaactaaa agtattgctg ctaatattat attgaatatt ggtcctgcta
    19741 caatagtact aaatctttgt aatatagact tgtttccaaa agaatttgga cttatttgtt
    19801 cttcatcttc accttccatg ctgacatatc caccaattgg aagtgctctt atagaatact
    19861 ctgtatcttt ttttacacta tatatcttag gccccatacc tatagaaaac tcatttactt
    19921 tgataccact tctttttgca aatataaaat gtcctaactc atgtattaat acaattatac
    19981 taaatagtat taatgcggct attatagtca taaattcacc ttcctatttt tttatcagat
    20041 ttgcaacata agctctactc catctatctg tttctaagat ttcttctaat gttggttcac
    20101 ttatgctact atgaacttct aaagtcttct ctatgtaata tggtatgtca tagaaaccaa
    20161 ttttatcctc taaaaattca cttactaaaa cttcatttgc tgaatttaaa acagaagaat
    20221 aagttcctcc catttttaaa cactcatatg ccaattttaa acatggaaaa gtttctaaat
    20281 ctggttcttc aaaagttaaa gtactaaatt ttgaaaaatt cattctttca aagctacttt
    20341 ccattctatc tggatatgta agagcatact gtattggtag tctcatatct ggacatccta
    20401 attgagcaat tattgagcta tctgtatact gcaccattga atgaattatg ctttgtgggt
    20461 gaactactac atctatattt tcttgttcta ctccaaataa ccatctagct tctatcactt
    20521 caagtccttt attcataagc gttgaagaat caatacttat ttttcttccc atactccaat
    20581 ttggatgctt caaagcttca tttttagtta tatttgcaag ttctcccttt ttctttcctc
    20641 taaatggacc accagatgct gtaagtatta tcttttctat atttttttta ttttctccat
    20701 ttagacattg aaatatagca ctatgttcac tatcaacagg aagaatattt acattgtatt
    20761 tttctgcttc tttcattaca agttcaccag cagttaccaa cgtttcttta ttcgctaatg
    20821 ctatgtctat tcccttcttt atagcacaaa gagttgggac taatcctatc atacctacta
    20881 cagcagttaa aaggacatcc acttcatcaa gtgatgatat tatttttaat ccttccattc
    20941 ctgctaaaac ttctatttct atatttttag gcaacatttc ttttaatttt aatgctttat
    21001 tttcctcaaa aactgttaca tatttaggtt taaactctac tatctgttct agcaataatt
    21061 caatattact gttagctgat attgcaacta tctcaaactt atctctatgt tctctaacca
    21121 catccaaagt ttgtttacct atagagcctg tagaacctaa aattgatatc tttttcatat
    21181 aataatcctt tctaataata aatataccct gtcaaaacat tataacacta ctaaaacaat
    21241 tatttttact attcatagaa atttcatata ttattccaca gattaaaatt aatctattat
    21301 tttttgtatt ttgtggaata ttataaaata ttctagtatt attaaatgcc cttttttatt
    21361 tccacaacat cttctatttt acagtctagt gctaaacata tcttctccat tgtatccata
    21421 gaaacagatt tatcatttcc tagtctgcct aaaacagaaa tacttatacc tgatatattt
    21481 acaaattcca ttttctttat ttttctgtca attaacaatt tccataatgg agcgtatgaa
    21541 atcatgttat cacctcgcaa aatatattct atcacatttt atctattttg gaaaattttc
    21601 atctatttag ataaataatc acctgcttaa gtgtcaaata attttatcct tctaatatga
    21661 aaatttaata ctatactaaa tgattggtat ataacacata tgatgcatta ttattaacat
    21721 ataaaaattt ttattggtgc taaattaaag t
//
LOCUS       DAEHWO010000069        21749 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEHWO010000069 DAEHWO010000000
VERSION     DAEHWO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21749
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.069"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            167..1618
                     /locus_tag="KNP54_002941"
     CDS             167..1618
                     /locus_tag="KNP54_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBF0893810.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1837..2298)
                     /locus_tag="KNP54_002942"
     CDS             complement(1837..2298)
                     /locus_tag="KNP54_002942"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBF0893811.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(2403..3596)
                     /locus_tag="KNP54_002943"
     CDS             complement(2403..3596)
                     /locus_tag="KNP54_002943"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBF0893812.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(3619..4284)
                     /locus_tag="KNP54_002944"
     CDS             complement(3619..4284)
                     /locus_tag="KNP54_002944"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBF0893813.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSNNHKSNIDKDFLFK
                     NGF"
     gene            complement(4318..5430)
                     /gene="ribD"
                     /locus_tag="KNP54_002945"
     CDS             complement(4318..5430)
                     /gene="ribD"
                     /locus_tag="KNP54_002945"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBF0893814.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKASNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(5562..5683)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            5872..8355
                     /gene="recQ"
                     /locus_tag="KNP54_002946"
     CDS             5872..8355
                     /gene="recQ"
                     /locus_tag="KNP54_002946"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBF0893815.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      8444..8555
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8697..9998
                     /gene="thiC"
                     /locus_tag="KNP54_002947"
     CDS             8697..9998
                     /gene="thiC"
                     /locus_tag="KNP54_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBF0893816.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            10052..10246
                     /gene="thiS"
                     /locus_tag="KNP54_002948"
     CDS             10052..10246
                     /gene="thiS"
                     /locus_tag="KNP54_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBF0893817.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            10239..11042
                     /gene="thiF"
                     /locus_tag="KNP54_002949"
     CDS             10239..11042
                     /gene="thiF"
                     /locus_tag="KNP54_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBF0893818.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            11105..11875
                     /locus_tag="KNP54_002950"
     CDS             11105..11875
                     /locus_tag="KNP54_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBF0893819.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            11892..12995
                     /gene="thiH"
                     /locus_tag="KNP54_002951"
     CDS             11892..12995
                     /gene="thiH"
                     /locus_tag="KNP54_002951"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBF0893820.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEVISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            12996..13685
                     /locus_tag="KNP54_002952"
     CDS             12996..13685
                     /locus_tag="KNP54_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBF0893821.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            13873..15267
                     /gene="yfcC"
                     /locus_tag="KNP54_002953"
     CDS             13873..15267
                     /gene="yfcC"
                     /locus_tag="KNP54_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBF0893822.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            15784..17151
                     /locus_tag="KNP54_002954"
     CDS             15784..17151
                     /locus_tag="KNP54_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBF0893823.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            17176..17784
                     /locus_tag="KNP54_002955"
     CDS             17176..17784
                     /locus_tag="KNP54_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBF0893824.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            17832..18203
                     /locus_tag="KNP54_002956"
     CDS             17832..18203
                     /locus_tag="KNP54_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBF0893825.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            18382..18720
                     /locus_tag="KNP54_002957"
     CDS             18382..18720
                     /locus_tag="KNP54_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBF0893826.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            19186..19689
                     /locus_tag="KNP54_002958"
     CDS             19186..19689
                     /locus_tag="KNP54_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBF0893827.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGVYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            19736..20695
                     /gene="moaA"
                     /locus_tag="KNP54_002959"
     CDS             19736..20695
                     /gene="moaA"
                     /locus_tag="KNP54_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBF0893828.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSITRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            20699..21169
                     /gene="moaC"
                     /locus_tag="KNP54_002960"
     CDS             20699..21169
                     /gene="moaC"
                     /locus_tag="KNP54_002960"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBF0893829.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            21205..21636
                     /locus_tag="KNP54_002961"
     CDS             21205..21636
                     /locus_tag="KNP54_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBF0893830.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         8388 a         2344 c         3755 g         7262 t
ORIGIN      
        1 gaatataaaa ctgcaatata ttaaaaaaat tattcatttt aaaccttgta atttgatttt
       61 ataaatatta taattaaatt aatgaatttt taacaaggaa ttattcattt ttttgatttt
      121 aagatttatt gagaaaacaa aactaaatag gggggtaatt aatataatgg attttttcaa
      181 tggtatttta acgagtatta acaatgcagt agtatatgta aacaattact tatggtcgta
      241 tatcttaatt ataatgttag ttgtaattgg tatttacttt actattaaaa caaattttgt
      301 acaattcaga tattttatag aaatgtttag acttctgggt gatggtacag cgaataaaaa
      361 tgcaaaaaag gaaggaaaaa tctcttcatt tcaagcattt tgtataagta catcttcaag
      421 agttggaact ggaaatatag ctggaatagc aattgcagtg gtagcaggag gacctggtgc
      481 tgtattttgg atgtggctta tagcattaat tggttctgca tcaagctttg ttgagagtac
      541 attagctcag atttacaaag tgaaagatgg tcaagctttt agaggtggac cagcgtatta
      601 tatggaacaa ggtctaaata aaaaatggat gggtatttta ttctcaatac ttataactat
      661 atgttatggt tttgtattta atgcagttca agcaaatact gtttcacttg catttaataa
      721 tgcatttgga ataagtaaaa tggctatggg aataggtctt ggaattttaa ctgcaatagt
      781 tatttttggt ggagtgcata gagttgcaaa agtttctgaa ataatagttc ctgtatttgc
      841 aggattatat atattagttg ctttggctat agttgtaatg aatataacag agataccaag
      901 tgttatagca ttgatagttg aaagtgcatt tgattttaaa ggaatggcga ttggtacatt
      961 tatgggagtt gtaatgactg gagtgaagag aggtctattt tctaatgaag caggtatggg
     1021 tagtgctcct aatgctgctg caacagcaca tgtaactcat cctgtaaaac aaggtttaat
     1081 tcaatcttta ggtgttttta cagatactat aataatatgt agttgtacag cattcatggt
     1141 attattatat tcaggttata gtagtagtgg agcaactgga attgaattag ctcaagaagc
     1201 tttaactcat catataggac cagttggaaa tatatttata gcagtttgta tattcttgtt
     1261 tgcatttagt tctatagttg gtaattacta ttatggtgaa tcaaatatgg agtttatgag
     1321 tggaagtaag actaaactta atgtatttag agtttttgtt gtaggtatgg ttttatttgg
     1381 ttcacttact caagtggatg tagtttggaa tcttgcagac ttatttatgg cattgatggc
     1441 gataataaac ttaatagcaa tagcactttt aggaaaatat gcatttattg ctttaaaaga
     1501 ttatacaagt caaaaaaaat caggaataaa agaccctgtg tttattgcag atgaaataga
     1561 aggcctagaa aaggtatcag agtggcatag ggaattatct gaggaacatt taggataaaa
     1621 aatagtataa aattataaaa ccattttgaa agactagagt atgtatatac tttatatgaa
     1681 tataatattg aattaattta tattactgga atttttaatt ccagtaatat ttttttatta
     1741 tataatttag ctttattaaa agtttttatt attaaaaata gcttatttat cgtaaagtga
     1801 atgatattgg gttttaatta ttatgaatgt tagtatttaa tttaaagact taaataaatt
     1861 tgccatttct agcgcattca tagcacaatc ataaccttta tttccagctt ttgtacctgc
     1921 tctttcaata gcttgttcaa tattttctgt agttacgatt ccaaatataa caggtaattc
     1981 actgtctaaa gatactttgg ctatcccttt agagacttca ctacatacat aatcataatg
     2041 agaagtagcc cctcttataa cacagcctaa acagattata gcatcatact taccactttt
     2101 agccattttt tgagcaacaa gaggaatctc aaaagctcca ggtacccaaa ctatttctat
     2161 attttctgga gaaacgtcat gtcttaaaag acagtcttca gctcctgata aaagttttga
     2221 tgttataaat tcattaaaac gagaatttat tatacctatt tttaaatctt ttccaataag
     2281 ttttccttca tatatcattt ttacttcctc caattttatt tatgttatag atttatattt
     2341 ataaatatct ttaatttaat tataaaaaac tacttagtag aaaaatatca tcatataatc
     2401 atttatataa tatctaaaag atgtcccatt ttatcttttt tagtttttaa atatagctta
     2461 ttaaagtcat taatttcttc attaataggg attctatttt cgatttttat tccatatttc
     2521 tctaattgat ttattttatc tgggttatta cttaaaagat ttatactttt tatgtttaaa
     2581 ttttttaata tttgagcagc catatagaaa tctctcatat cttcttcaaa tccaagcatt
     2641 aaatttgctt caacagtatc gtaaccttct tcttgaagtt tataagcctt aattttattt
     2701 aaaagaccaa tacctctacc ttcttgcttc atataaatta aaactccact tccattttcc
     2761 acaattttct tcatagaaga ttctagctgt aatccacaat cacattttag agagtggaac
     2821 acatctcctg ttaaacattc agaatgaagt ctaactagag tattttctat atttatattt
     2881 ccataagtaa gggcaatgtg ttcttcattt gaataagtat ctctatatcc tatgatttca
     2941 aaatttccat attttgtcgg aaggaaagca ctagatactt tttctatagt agtttcattt
     3001 attttgcggt attctataag gtcttttata gtgatgattt ttaaattatg cttttctttg
     3061 aaaatcatta aatcatcaac tcttgccatt gtaccatcat ctttcattat ttcacagata
     3121 agaccaatct ctttaaaacc tgcaagtcta gcaaggtcta ctgaggcttc tgtatgtcca
     3181 tccctgacaa gaaccccacc agtttttgct attaaaggaa agatgtgacc aggcgttttg
     3241 aaatctttac ttgtagaatt ttcatcacag aataatttta cagtttcagc tctttcatat
     3301 gcagatatac cagttagagt atctgctcca tctatagtaa cagtaaaggc tgtttgaaat
     3361 gtatctgtat tttctctaac cataagaggt atattaagac ttttaaattt tttttcagtg
     3421 gcaggtagac aaattagacc tctaccatat gtagccataa aatttattga ttcaggagta
     3481 gccatttcag ctgccatcaa taaatctcct tcattctctc tactttcatc atcaaccacg
     3541 attaccattt tcccattttt tatatcttca atagcttctt caatagtatt aaacatgtaa
     3601 ttcactcctt tattattttt aaaaaccatt tttaaataaa aaatctttat ctatatttga
     3661 tttatggtta ttactattag aatttaattc cttgtagtta ttagccataa aattattaac
     3721 atactttcca attacatcgc tttctaaatt aacgaaatct ccaacattct ttgtcaagag
     3781 aatagtgtta attttagtat gaggtataat agaaacctta aatatttcat catctaaata
     3841 tgatatagtt aaacttacac catcaatagc aacagaacct ttgagtatca ttgaggataa
     3901 aagtttttta tcaggtcgta tacttactaa aactgcattt tcatcttttt caaatttgca
     3961 gatagttcct ttaccatcaa catgacctgt tactatatga ccaccaaatc ttgaagaaag
     4021 actcatagct ctttcaagat ttaccttgtc atttgcattt aataaaccta aatttgtgga
     4081 acgaattgtc tccatcataa catcggctgt aaattcattt tttccgaggt ttgaaacagt
     4141 tagacaaact ccatttacgg ctatactatc tccaagattt gtgccatcta atattttatt
     4201 tgatagtatg gttacttttc cactcttacc attagcagta atttttctaa gtattccaac
     4261 ttcttctact atgccagtaa acatcctaac ctcctatatg aatgtattaa caaaaattta
     4321 atttaaaaca tctgattcta taagaatatc gccatctatc aaagttacat tattgattgt
     4381 taactgtgtt gaatctgaca aatgatttat tccttctcca gaaacgaatg taggtgcatc
     4441 tttaccacct ataatcttgg gtgatagaaa taatttgacc ttatcaacta acttatttct
     4501 aaagagactg tcattgagag tagcaccacc ttcaactaga acagaatcaa tgtttaactc
     4561 tcctaattta tacattacaa actccaaatc tactaagttg ttttttgaag gagaaattat
     4621 tgtttcaaca ttattttctt ttaacataga taattttata ctttctttgc aacatgtgaa
     4681 aactatagtt ttactggttt tatctttaac caaattacta ttaagtggca actttaggtg
     4741 tgtatctatt actattcttg taggatgaga cactttttct tgattgagcc tacaagttag
     4801 taaaggatta tcgttcaaaa ctgtatttat gccaaccatt atactttggt atttatttct
     4861 gtatttatga gttagatacc ttgatgattc attagatatc cattttgatt ctagtgattt
     4921 tgtagcaatt ttaccatcta gacttactgc tgattttaca atacaaagag gtcttttgtt
     4981 ttttatatga taaaaaaatg cctcatttaa atctcttgct tcatcttcta atattcccac
     5041 agtaacatca atattgttat cttttaattt ttttactcca ttaccacaaa caagtggatt
     5101 tgggtctaat gtagatatta caactctctt aatcttattt tgtataattt tatctacaca
     5161 aggaggcgtt ttcccataat gagaacatgg ttctaagttt acataaagag tagagtcttt
     5221 tagactttgt ttagcactgt ttatagcatt tacttcagca tgattagagc caaatttctc
     5281 atgatatcct ttgcctatta tattactagc tttaacaatt acacacccaa ctaatggatt
     5341 tggatttaca aagccttctc catttttagc caattcaata gcttttttca tataataaat
     5401 atctttttct ttttgattca caaaattcac aatatgtaca cctcctgttt aattggataa
     5461 tttttaaaca aaaaaccctg agaattaact cagggtttag aataatctac aataaatgtt
     5521 taataaatgt agaacaaaat tgctctacaa aaacactcat taaatatctt cttccatcca
     5581 gactttactg tcggctttgg aatttaacca aatcaaccaa gttttacctt ggctcgcggg
     5641 ctataccgcc gattgggaat ttcaccctac cccgaagatt aagtattaaa tttatattta
     5701 gaatgtatca taaattattt tactttgcaa actatttttt taaaaaatat atgttaatat
     5761 ataatataga atgtctataa actttgaaat accacgattg tgaatataaa aataaaaatt
     5821 tgaacataat caggaaagaa gtctaattaa tttaaattag gagagtaata tatgaataaa
     5881 aaacttttag aaatactatc aaaatactat ggatatacaa gttttagaaa aggtcaagaa
     5941 tctataataa actctatctt aagcgaaaaa gatgtgttag ctattatgcc aacaggaggg
     6001 ggaaaatcaa tatgttatca aattccagct ttgattttag atggaatgac aatagtaatt
     6061 tctccactta tatcacttat gaaagaccaa gtagatgcct taaagactat gggaattagt
     6121 gctgctttta taaatagttc attaagtagc aaagaattta atgaaatatt aaataatatt
     6181 agaaaaaata attataaaat actctatatt gctccagaga gattagatgc acaagagttt
     6241 attgagctaa taaataataa caatgtaagt caagttgcga tagatgaagc acattgtgta
     6301 tctcaatggg ggcatgattt taggttgagt tatagaagga tttctgattt tataaaaaat
     6361 ttgcctaaaa gacctatagt tacagcattt actgcaacag cttcagaaga ggtaagaact
     6421 gatataataa atttactgtg tttagaaaat ccagattatt atataactgg atttgataga
     6481 gagaatttat caataaatat agtaaaatca tctagtaaaa ataagtatat tttagattat
     6541 attcaaaatc ataaaaatga gtctggaatt atatatgttg caactagaaa ggaagttgaa
     6601 aatatatata atggtttatc taagagaaat atatctgtgt caaaatatca tgcaggttta
     6661 tctaaaaatg aaagaagtaa aaatcaagaa gattttataa atgataatgt ggatataatg
     6721 gtagcaacaa atgcatttgg aatgggtatt gataaaccta atataagatg ggttatacat
     6781 tacaatatgc ctcaaagtat agaaaactac tatcaagaaa taggtagagc tggtagggat
     6841 ggagaaaaaa gtgagtgtgt acttttattt tctccaggag atgtacatat acaaaaatat
     6901 ttaattgata ttggagttga aaatcctgaa agaaaattat ttcagcataa gaagcttcaa
     6961 tacatgattg acttagttta cagtaattca tgctatagaa agacaatatt gagttatttt
     7021 ggagaaaatt atatagacaa ttgcaataat tgtagcaatt gtttagtaga gggtgaaata
     7081 gtagataaaa ctatagatgc acaaaaagtc atttcatgtg tagctagaat gaaaagaagt
     7141 tatggtgtta ctactattgt agatgtgctt agaggttcta agaataaaaa gattttacag
     7201 cttggattaa atactttgtc tacatataac attatgagag attattctag tgaagactta
     7261 aagaattttg taaatacatt ggtttctcat ggttttttag atttagttga gactctaggc
     7321 aatggaaata gaggtagttt tcctactata agattaaatg agatgtctat gaaagtttta
     7381 aaaggtgaag tgaaagtaga gtttaaagaa attgttatga caaaatcatt ggaagtagag
     7441 gatgagttat ataatgcttt aagagaactt agacattcaa ttgcaagtga agaaaggata
     7501 gctccatata tggtatttgg agatggtaca cttagagcca tgtctagtag ttatccaatt
     7561 aataaagaag aaatgctaga tatctctgga gtaggagaaa ttaaatatca aaaatatggt
     7621 agagattttg aagcagtaat taaagaatat gtcgaaaaaa ataatataaa taaaaaaata
     7681 gatgaaaaaa atgtcgattc aaagaacgtt aatagtgatt tcttagaggt taatacagat
     7741 aaagttttat atgaaaaact gttagtcatt agagaagaat atgcaacaaa ggaaaaatta
     7801 cctgcatata tgattttagc caataaggct ttgaaagaaa taagtggaag atatccactt
     7861 gatgaagaac aattaaaaga tatttctggc ataggtggag taaaatttga aaaatatgga
     7921 gctagtattt tggcagaggt taataaatat gtaaaagaaa ataatattaa tgttatttgg
     7981 gagaaaaagg gcaaaaggaa gttaatatta gatggagaaa gtagaaaaaa taatgaaata
     8041 gcattagatt tgctaaatca aggaaaagat atacaaagta tcagtcaaga aatagaagtt
     8101 tcactgtcaa ccattattgg atatgtgcat gactatgtaa aggatggaca tagtatatca
     8161 tttgaattag gactagaaaa tttttataat gaagataaaa agaagatgat tttagaagtt
     8221 tgcgaaaaag ttggctatga taatttaaat aacataaaaa gaaaacttcc agattcaata
     8281 aagtatgaaa atataagagc tgtgatactt gactcttatc ttgaaaactt aaaaaataat
     8341 attatagcag agtaattttt aacttaataa aaaataaaat ttgtattatt gtgttgaact
     8401 aataattttg ctgtgttata ctgaatttgt aaaaataatg aaaaattaga gctaggggcg
     8461 ctagaattgg ctagctgaga gataaagccg taacttacaa accctaataa cctgatcaag
     8521 ataatgcttg cgaagggaag ctttttaata taattttatt atataaatag gcaaattatt
     8581 caatgttagg agaaatttgt ctaagtgtat atacgattat aagagtgctt tccaaacgag
     8641 gaaaagcact ttttttattt tcaaaaacta taactttaat cttggaggat tgtaatatga
     8701 actatacaac acaaatggat gctgctagaa aaggcataat aactaaagaa atggaaatcg
     8761 tttctcaaaa agaacaggta gatgtaaatg aattaagaga attaatagca aatggacaag
     8821 ttgttatacc agctaataaa aatcataaat ctttaagtgc agaaggtgta ggtaaaaatt
     8881 taagaacaaa aataaatgta aatctaggaa tttcaagaga ttgtaaggat atagaaaaag
     8941 aacttgaaaa agttagagta gcaatagaca tgaaagctga agctataatg gatttaagta
     9001 attatggcaa aactagagaa tttagagaaa aggttgttga aatgtcacct gcaatgatag
     9061 gttcagtacc tatgtatgat gcagtaggat atttggaaaa agaattaaaa gatataacag
     9121 aagaagagtt tttaaatgta ataagacaac atgctattga tggagtagac tttattacta
     9181 tacatgcagg tcttacaaga agtgtttgcc aaaaaataaa aaatcatgag agattgactc
     9241 atatagtatc tcgtggaggt tctttattgt ttgcatggat ggaattaaat aataaggaaa
     9301 atcctattta tactaatttt gataaaatat tggatatatg tgaagaatat gatgttacat
     9361 tgagtttagg agatgcttgt agaccaggtt gtataaaaga ttctactgat ggtgttcaaa
     9421 ttcaagaact tgtagtatta ggtgaactta ctaaaagagc atgggaaaga aatgtacaag
     9481 taatgataga aggtcctgga cacatggcta ttgatgaaat agaagcaaat gtagtattag
     9541 aaaagagatt atgccatgga gcaccttttt atgttcttgg accattggtt acagatatag
     9601 caccaggtta tgaccatata acaagtgcaa taggaggagc tttagcatgt gccaaaggag
     9661 tagatttttt atgttatgta actccagcag aacatttaag attgcctaat ttagatgata
     9721 tgaaagaggg tataatagct gcaaagatag ctgctcatgc aggagatata gctaaaaatg
     9781 ttaaaggtgc tcgtgaatgg gataataaga tgagtaaagc tagagctgat ttagactggt
     9841 gtgagatgtt tagacttgca atagaccctg aaaaagctaa gagatacaga gatgaatcaa
     9901 ctcctactca tgaggatagt tgtactatgt gtggaaaaat gtgctcaatg agaacagtta
     9961 agaaaatatt aaacaatgag gaacttaatc taatataatt tttggctagt atgactggaa
    10021 taaaaataag ctgaaaagag gaggtgattt agtgaaggtt aatgggaagg aaattgaatt
    10081 tgaaaaagat ttgactgtta tagatttatt aaataaatat aatttaaaaa gtgatagagt
    10141 tgtagttgaa gtgaatttag agataattga agaatctaac tacaatacat atgtattaaa
    10201 agacgaggac attgtagagc ttattagctt tattggaggt ggttaaaata aaaatatttg
    10261 taaatgaatt attaacagat gttgaggaaa atacaactgc ttataaagtt agagatagct
    10321 ataacaataa atgtgatgta ttggtgttaa atggatatcc aattaaaaca gatatgaccc
    10381 tttgtgaaaa tgataaatta acacttatac aaaaaggagt taagccatca cttgatgaat
    10441 tggaaagctt gttgattgct agacatactc caaatataca taataaatta aaaaaaggga
    10501 aagttgctat attgggattg gggggacttg gttccaatat agctatctct ttagctagaa
    10561 taggagtggg agaactttta cttatagatt atgatgttgt agaaccatct aatttaaata
    10621 gacagcagta ttttatagat gatataggaa aactaaaaac tgatgccatg atagaaaata
    10681 taaaaaaaat aaatccattt ataaaattaa ataaacgaga tattttttta aacaagaaca
    10741 atatggatac tattaaggat tcagatttaa taattgaggc ctttgatgat gcttcatgta
    10801 aagcacaggt atgtaattat gtattaataa atttaaaaga taaatattta atagcatcat
    10861 ctggtatggc aggttactat gattcaaata taataactac taagaagata aaagacaggt
    10921 tttatatatg tggggatttt gtgaatgaag ctaaatttgg tgaagggctt atggctccaa
    10981 gggttgccat ctgcgcaaat catatggcaa atttggcaac gcaaatactt atagatatgt
    11041 aaatattaaa attagatata aaaaagattg aatattaaaa aaatttaacg tggagggaaa
    11101 taatatggat aaattggtac ttggtggaca tgaatttaat agcagattat tggttggaac
    11161 aggtaaatat ggttcaaata atatattgcc tgaggtaata aaagaaagtg gaagtgaaat
    11221 aataacaatg gcacttagaa gagtggattt agacaataaa caagaaaaca tattaacgta
    11281 tattccaaaa gagatgacaa tacttccaaa tacatcagga gctactaatg cagaagaagc
    11341 tgtaagaata gctagaatat ctagaaaaat gggatgtgga gattttataa aaatagaagt
    11401 aatatcagat actagatatt tacttcctga taatgaagaa actataaaag ctacaaagat
    11461 acttgctgat gaggggttta tagttcttcc atatatgaca ccagaccttt atgctggaag
    11521 aagacttata gaagctaatg cagcggcagt tatgccactt ggagctccaa ttggttcaaa
    11581 tagaggtctt caaatgaaag aaatgataag aataatgata gatgagttgg atataccaat
    11641 aatagtagat gcaggtattg gaaaaccatc tcaagctatg gaggctatgg aaatgggagc
    11701 tgatgcagta cttgtcaaca ctgctatagc ttcagcagga gaccctgtac aaatggctag
    11761 agcatttaaa ttagctgtag aaggtggaag agaagcatat attgcaaaaa caggaaatgt
    11821 gtcagaattt gcaaatgcat cttctccttt aacaggtttt ttaggcaatt tatagaaagt
    11881 ggtgattggt gatgagtttt tatgatgtaa tagaaaaata tagggatttt gattttgatg
    11941 gatatttaaa taatgttact gataatgatg ttttaagaag tttatcaaaa gacaagcttg
    12001 aagattttga tatattaaat ttgctttcta aaactgcagt aaaacattta gaagatatgg
    12061 cacaaaaagc acataaatta agtgttcaat actttggtaa aacagtatgt ttatatacac
    12121 caatgtatat agcaaattat tgtgttaatc aatgtgttta ttgtagctat aatataaaga
    12181 gtggaataaa aagaaaaaaa ttaactatgg atgaaattag agaagaggga gaagtaattt
    12241 caaaagaagg tttcaaacat ctacttgttt tgactggaga aagtagtttt cactcaagtg
    12301 tagaatatat aggtgaggct atagaaatat taagagagaa atttccctct ataggtatag
    12361 aagtttatcc aatggaagta gaagaatata agtacattgt agataaaggt gttgaaggat
    12421 taacagtata tcaagaaact tatgacgagg aaatatataa gagagtacat ataaaaggcc
    12481 caaaatcaaa ttataaattt agactagatg ctcctgaaag aggggcaaaa gcaggtatga
    12541 ggactttatc aataggtgca cttttagggc taaatgattt tagaaaagaa acttttttta
    12601 caatattgca tgggaaatac ttaaaaacga aatatcctca tattgagctt tcatattcaa
    12661 caccaagaat gagacctttt aaagggtgtt ttgaggaatt ggtagatata agtgatactg
    12721 atttagttca agctatggta tgtatgagat tatttgaccc tcatgcagct ataaatatat
    12781 ccactagaga aaatttagaa atgagaagtc atataatacc tttaggagta actaaattga
    12841 gtgcaggtgt atctactgat gtaggaggtc attctcaaga tgaacatgat actgctcaat
    12901 ttaagataaa tgatgaaagt actgttaaag atgtggagaa aatgctaaac tcaattggtt
    12961 atcagcatgt gtttaaagat tgggaaagat tttaaatgta tctgataaca aacagaaaat
    13021 tatgtagtga ggaacgatat ttagaagtta ttaaagagtc tatattgagt ggtgtagaaa
    13081 atataataat aagagaaaag gatttagaat atcaagagct aagaaaatta tatatgaaaa
    13141 taaaaactaa aatcaattgt atagattttc aagagcaaat atcagatgaa agtttgaaaa
    13201 ctaatataaa tcaaaaagag tttagaaata aattcaaggt taattttata ataaatagta
    13261 acattgaatt ttttgaaaaa gtggattgtc aaggtatcca tcttcctttt aaattattct
    13321 tgaatttaat tgaaaataag tataatttta atgaaaataa aatactagga ttatctttac
    13381 ataaagtaga ggaagtagat tatttagaaa aattaataag aaatcaaaat ataaaaatag
    13441 attacataac attatcacat atatatgaaa ctaaatgtaa agaaggatta aatccaaaag
    13501 gaattgagct tttaaaagaa gctaaaaaga ttactgatat taaaataatt gcacttgggg
    13561 gaattttacc atctaatgtc aaggaaacat taaaatactg tgatgatttt gctataatgt
    13621 caactataat gaggtctaaa gatattaaaa aaaccatatc aaattataat gaaaagttga
    13681 attagtaaat atagtatatt gaatttttaa cttaaataaa aataaaaaag ttatctttta
    13741 aattttaaaa ggtagctttt ttattttata tctttgctaa taaaaaattg taaaaaggga
    13801 aaactttagt cagagagatt aaacaatatc ctagaaagat ttaaaattta gtaaagtatg
    13861 gaggacatta taatgactga cagtaaaaag aaacgattta ttataccaca cacttttaca
    13921 ataatatttt tactaatagt cttgatggca atattgactt ggatagtacc aagtggtgaa
    13981 tttagtagag aagatgtaga aggtagaatg gtagttgtac cagggactta tcaaagtgta
    14041 gaaagtaatc ctcaaggatt tgcagatgtt tttaaagcac caatagaagg ctttatcgat
    14101 tcagctgaag ttgtaggttt tgttttaata gttggaggtg cttttggtat tgtaaatagg
    14161 actggagcta tagaagcagg aatagcttcg gttatctcta agtttaaggg aaaagaactt
    14221 cttataattc caatatcaat gattttattt ggacttggag gtacaacatt tgggatggca
    14281 gaagagacat taccatttta tatgatattt gttccactca tgacatcctt gggatatgat
    14341 tctctaacag caatagcaat tgtatttata ggagcagcag caggagcagc cgcttcaaca
    14401 ataaatccat tttcagttgg tattgcacag gcactagctc aacttgctcc tggttcagga
    14461 gtaacttaca gagtagttat ttttatagca tatatactaa taagtatagc atttgttatg
    14521 tactatgcta agaaggtaaa ggaaaatcct gaaagttcaa tagtatatga aatagataaa
    14581 aataataaat caatacttaa tcaaacttca acagaaataa aagaatttac ttttaaagaa
    14641 gtatctgttc ttgctatatt tggaataggg atggcaataa tgatttgggg tgttttaagt
    14701 caaggatggt acattccaga aatatcaatg tgttttgctg caataggtgt gctttctgga
    14761 ttggttggta gattatctca aattgaaatc tcagaaagtt ttatagatgg agcaaaagat
    14821 ttagcatctg cagctcttgc tatagctttg gctcgtggaa tcgtaataat tgctcaaaat
    14881 ggatttataa tagatactat attaaattcc gcagcagcct ttctaggtgg gcttccaaag
    14941 gttatatttg tatatttatc atttttcttg gaagctgcat tggcattttt aattccatca
    15001 tcttcaggtc ttgcttcact tacagtacct gtacttgctc ctcttggtga tttggttaat
    15061 atatcggctc aagtgatagt aaccgcttat caatttggtg tgggtcttac aaactttata
    15121 actccaactt caggagtact gatgggagca cttgcagtag cccatattcc attttcaaaa
    15181 tgggtaagat ttataatgcc tatcttgttg attttgacag ctgtatctct agtcttttta
    15241 acaataggta tttatatagg gttttaatta agtgtagttt tatttaagat atttagtaat
    15301 ggtataaaat gataatatgt tttcaataaa ttgccactaa tttaattagt ggtaatttgt
    15361 tttttgtatt taaaaataaa tgtatttact tgtattttga attaatatct acttagacat
    15421 tgttttaatt gttatatttt tatttaatta agcattgatt tatcattttt tatatttcat
    15481 ataacaatgc aaaaaataat ttttatatag taaatgacaa aagtttacaa taaatgtata
    15541 ttttcttact cattccttaa aattactcat ttagtttaat aactctcatt tcatatgtaa
    15601 agttggtaaa aaaattaaaa ttaaaagtaa aaaactaaat aaattaatgt taatttgaaa
    15661 tatatatgaa ggtttttgga gaatacttac ttatgatagg aaaaaatgtt aaaataatag
    15721 tgtaatcaaa tataaaggac tgaaataatt aacagttatt aaatattagg agtgtaaaaa
    15781 tttatgggat taaaagaatt tgattttatt gaagagtcta ttgatatgtt gaggacaatg
    15841 tcaccaacat tagaaactat atcagatgaa atagaagaat attttgaaaa tatcttggat
    15901 gaaaagaatc aagaatatat aaatgtaacc tctagaataa aatcagaatc aagtttaaga
    15961 gaaaagataa ttagaaatag atatttaaaa aaatatggag aagcaagtaa tcttattcat
    16021 aatgtttctg acttaatagg cctaagaatt gagtgtagat ttattgagga tgaaaacaaa
    16081 atatatagac ttttgagaag atattttaat aaaacagatg acaaaataaa ctattataat
    16141 aaagagaata agaatattaa attaaaacta tctgagaggc aacccaataa gcaaaaaaat
    16201 ggatttgaaa tatataaaat agatggagtt tttgcgtatt tagatagaga agtaaaattt
    16261 gaacttcaaa ttaaatctct tgtaaatgtg ttttggagtg aaatagaaca taaaataatt
    16321 tataaaaaca atacatattt acttgctgat aaatttataa aggatatgat ggactctata
    16381 aagaataatc ttactatgat agataatcag cttttaagta tttataaaaa ctttcattca
    16441 gggaagtctt ttaatatgaa agtaagtaaa aaagaaattg aaaaattatt tgcgaaacta
    16501 gtctatgacg ctttttctga aaagatgaat aaaagtatag gttttgttgt agattttaaa
    16561 aaaccatgtg agactatatt gaactattct tttaataaac aagatataag tgatgaagtt
    16621 ttaggtaatt ttatgcttga tgagtttgca agattaaatg aaattgtaaa caaggatata
    16681 gattttaatg agcaaataga atttgaaaga gaaccaacat ttgatgataa gttttgtaaa
    16741 gacctaggaa atcattttag aagtagatta aacacagaat ttccatggaa cctatttttt
    16801 agaatattat ttgaaataga gccatataac aataccaaag actttgaaaa ctttgtagag
    16861 tttataaaag aaaatgtgct actagaagaa aatagggagc aattattatg ccaatttgaa
    16921 gaggatagta agcttataat tgaagatata tatgattgta tatttaatag tataagtgag
    16981 attgatagtg ttgaaatttt atataactat aatcttgaaa aaataaactt tacatcaagt
    17041 gaaatcataa attgtatatg tagagaatat gagtgttatg gtgaatactt agaagaaaaa
    17101 gaaaagctta tgaatacatt taaagaaaag attattcaaa tctttgagta ataggtcaat
    17161 gctgaagtgg cgctaatgcg ccatttttca aatatatatg aattaagtaa aattattttg
    17221 gaggaggcga tttgtataga gaaaacaggt gtaattttgg cagggggaaa aaattctaga
    17281 atgggtagag ataaagcctt tttagagtta catgataagc tttttattga aattgcaata
    17341 gaagcattta aaaactttga tgagttgata ataatatcta acaatgaaga attatattct
    17401 aaatacgata ttaaagttta taatgatata gtaaaagatg ttggtccaat tggaggaata
    17461 tatactgctc ttgaatatgc aaagtatgat atagttacaa ttgcatgtga tatgccatat
    17521 ctaaataatc aaatagtcga aagaatagct aataaaatgg atgataaaag tgtgatttca
    17581 gtgacaaatg gaaagttaca accattgtgt tctggatata aaaagagtat aataaataaa
    17641 gtatctttat gtataaggga aaatgattta aagctcagaa gctttataga taaaatagat
    17701 aaaagttata tatactttga tgaagaagat ttatttttaa atgtaaacac tgttgatgag
    17761 tataaaaaat taactaaagt ttaattagct atggttgtaa aatagagtag gatttatatg
    17821 gaggagagtt tatgaattta cttaaatgcg attcttgggc agtaatatta aataatagcg
    17881 ataaagaaag taaagcatat aaaatattag atgaacttaa aaggaatatg tacaaagttg
    17941 ttgctataga tgaagagaaa aaacctattg aaggaataga tgtgtatgaa tgtttaaaag
    18001 atgttccaca caatattgat gttgtagcta ttattgataa acaatctaag atggatgtga
    18061 ttttagaaga agtagagctt ttggatatac aaaatatgtg gtttgaaaaa ggaagcttta
    18121 gtgaaatgat gattaaaaag actaaagatt taaaattaaa tatagaatat aatttaagtt
    18181 tatatgatga gttgactaga taaaattata tttcttaata ataaaaatat aattagttaa
    18241 taaaacatat tattttatag tatagattgg ttaataaaag tacagattgg ttaatgaaac
    18301 attaaattac aatatttgtt aaaaaaattg tgagttacat gatataatgt attaaatagg
    18361 atactaagga gttgatatat tatgttaata gtaactacag aaaaagtaga aggtaaaaag
    18421 atatcaaagg ttttaggatt agtgagagga agtacaataa gagcaaaaca tgttggaaaa
    18481 gatataggag caagttttaa gaatcttgtt ggaggagaac ttactggata taatgaaatg
    18541 ctcactgaag caagacaaat tgccataggt agaatggttg aagatgcaga agctaaaggt
    18601 gcaaacgcag taatagcatt tagactgtct tcagcttcag ttatgcaagg agcagcagaa
    18661 atgcttgctt atggaacagc agttgtttta gaagatgata atagtattct tgaaaaataa
    18721 aatataaata gttaaaaaga ggcatctttt aaaaatttta tggatgcctt tttttatttg
    18781 aaaaaactaa tttgagaaga aattttaact attatgacaa taaaattagg gtgatattat
    18841 ataaataagt aaaattatat tatataatgt atggtataga ctttaaaaat tttatttgta
    18901 gagaaaaata tggacaatgt tataataatt atagaaatta aaagtactta cattcattat
    18961 gtatgtgaca tgtataatta gttttatatt taatacagtt ttgaagtaat atcttcattt
    19021 tgagaacgtt ggaataataa aaaatgtatt attataggtg atataaataa aaaataaata
    19081 taatatgtta tattgctgat agaaaagaga ataaaagaaa ataggtttta ttaaaagaga
    19141 tttttattta taggacttaa tcaatgtata gaggggtgag aacatatgtt taatgttgca
    19201 attataacac ttagtgataa aggatatgaa ggaaaaagag aagatataac aggaaaaaag
    19261 ttaactgaat ttgttgaaaa tacaggagtt tataaagtta ctgaatatgt acttataaaa
    19321 gatgataagg aaatgctaaa ggaaaatatt ataagacttt gtaatagtaa taaaatagat
    19381 ttaattctta caaatggagg tactggtttt tcaaaaagag atataacccc agaagcaact
    19441 aaggaagtgt tggaaaaaga aataccaggt ctgagcgaat atatgagaat gaaatccaca
    19501 gaaattacta aaaaggccat actaagtagg ggtgtgagtg gaataagaaa taattctata
    19561 ataataaatt tacctggaag tcctaaaggt gcagttgaaa atctaagttt tataattgat
    19621 gttttagacc atggcataga agttttaaga ggagaagcta cagaatgtgc cactaaaaaa
    19681 agtgaatagt atataatcta gatagataaa aaatagacaa agaggtagat aaagtatgat
    19741 tgataagtat ggaagaaaaa tagactacct tcgtatttca cttacagata agtgtaattt
    19801 aaggtgtgtc tattgtatgc caccagatgt aaaatttgat aaaaattata taaatgaaaa
    19861 tctaagcttt gaagactaca agtttattat aaaggctatg gctgaacaag gtataacaaa
    19921 aattagattt actggaggag aacctctttt atatcctaaa ttaaatgagc ttataaaatt
    19981 tacaaaagaa gaatgtggaa taaataacat aggaatgacc actaatgcta ttggtctttc
    20041 tgatagaatt tttgagcttg aaaaatgtgg cttaaataaa gttaatataa gtttagattc
    20101 tttgaaggaa tataagtata aatccataac aagaggagga aacttaaaag atgtcttaaa
    20161 atcgattgaa tcttgtttaa atttaggtat aaaagtaaag ttaaattgcg ttgctataag
    20221 tgggtttaat gatgatgagc ttaaagattt tatgttttta acagttaaat caccaattga
    20281 tgtaagattt atagagctta tgccattagg tgaggctaat agagtttata agaagggtta
    20341 ttttaatgta aaagaaatga ttgaaaaaat atatggttta tataaagtca aaaatgatga
    20401 aaaaagtaca gcagaatatt atatgtttaa aggagctaaa ggaagaatag gaattataac
    20461 tccattaagc tgttcatttt gtaacacttg taatcgtatt agacttactt ctagtggtgc
    20521 aataaaatta tgtctacatt caaaagaaga aatagatata aaaccatttt tacataaacc
    20581 attgttattt agagaatcta tgaaagatat aataaaacaa aaaccagaaa aacatcattt
    20641 aatagaaaat aaatgtagtg atacaaatag gcgtatgtat gaaattggag gataagtaat
    20701 gttaacacat ataaatgaaa aagggtatgc caagatggtg gacataagtg aaaaagatga
    20761 tactaaaaga acggccgtag ctacagctac aattactctt agtaaggaag cattagaaaa
    20821 agtaaaaaat ggtcagataa aaaaaggaga cgtattgtct gtagctcaag ttgcaggtat
    20881 aatgggagct aaaaatacat cttcaaacat accaatgtgc catcagatta aattagttgg
    20941 atgtgattta gaatttgatg tagatgattc tatgtctgct attaagatat acgcaacctg
    21001 taaatctctt gggaaaactg gagtagaaat ggaagcttta aatgcatgtt ctttagcagc
    21061 acttacaatt tatgatatgt gtaaagcagt tgataaaaaa atggttataa gtaatatcca
    21121 tcttgtggag aagactggtg gaaaatcagg agattttaag ttcgagtaaa ttaataatat
    21181 attgggttaa aatttggagg aaatatggcg aaggtagtgt caataaatat aagtgagaaa
    21241 aagggtgtaa ttaaagttcc tgtacaatgt gcagagctaa aaataaatca tgggatagtt
    21301 ggagatgcac atgcaggaaa ctggcatcgt cagataagct tacttggaaa agaaagcata
    21361 gataaaatga aaatgaaagg ctttgaccaa ttaaaatatg gagattttgc tgaaaatgta
    21421 actacagaag ggatagaagt tttttccctg cctgttggta caaagttaag aatagggcaa
    21481 tgtgaagttg aagtaactca aatagggaaa aaatgtcaca atggatgtga aattaagaaa
    21541 ttgacaggtg actgtgtgat gccacgagaa ggaatttttg taaaggttct aaaagaagga
    21601 attataaatg tgaatgattc aatagatgta atctaatgaa gtcactatta aaatataatt
    21661 ataagtaaat actattaaga tttaaatata tattttaaga gagaattaat tttaataaaa
    21721 tattttagtt ataaattgga atattggtt
//
LOCUS       DAEHWO010000070        21748 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEHWO010000070 DAEHWO010000000
VERSION     DAEHWO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21748
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.070"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            254..955
                     /locus_tag="KNP54_002962"
     CDS             254..955
                     /locus_tag="KNP54_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBF0893831.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     KKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            981..1637
                     /locus_tag="KNP54_002963"
     CDS             981..1637
                     /locus_tag="KNP54_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893832.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            1793..3433
                     /locus_tag="KNP54_002964"
     CDS             1793..3433
                     /locus_tag="KNP54_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBF0893833.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            3791..5113
                     /locus_tag="KNP54_002965"
     CDS             3791..5113
                     /locus_tag="KNP54_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893834.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            5310..6317
                     /locus_tag="KNP54_002966"
     CDS             5310..6317
                     /locus_tag="KNP54_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBF0893835.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            6355..7782
                     /locus_tag="KNP54_002967"
     CDS             6355..7782
                     /locus_tag="KNP54_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBF0893836.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SVGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLFASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQIYMGVEE"
     gene            7924..9189
                     /locus_tag="KNP54_002968"
     CDS             7924..9189
                     /locus_tag="KNP54_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0893837.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAE
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            9231..10829
                     /locus_tag="KNP54_002969"
     CDS             9231..10829
                     /locus_tag="KNP54_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBF0893838.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            10864..11886
                     /locus_tag="KNP54_002970"
     CDS             10864..11886
                     /locus_tag="KNP54_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBF0893839.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(12382..13785)
                     /locus_tag="KNP54_002971"
     CDS             complement(12382..13785)
                     /locus_tag="KNP54_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0893840.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            14958..15467
                     /locus_tag="KNP54_002972"
     CDS             14958..15467
                     /locus_tag="KNP54_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBF0893841.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            15495..15689
                     /gene="rpmI"
                     /locus_tag="KNP54_002973"
     CDS             15495..15689
                     /gene="rpmI"
                     /locus_tag="KNP54_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBF0893842.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            15745..16101
                     /gene="rplT"
                     /locus_tag="KNP54_002974"
     CDS             15745..16101
                     /gene="rplT"
                     /locus_tag="KNP54_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBF0893843.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            16411..16956
                     /locus_tag="KNP54_002975"
     CDS             16411..16956
                     /locus_tag="KNP54_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893844.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKKDEGK"
     gene            17391..19316
                     /locus_tag="KNP54_002976"
     CDS             17391..19316
                     /locus_tag="KNP54_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBF0893845.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            19717..21621
                     /locus_tag="KNP54_002977"
     CDS             19717..21621
                     /locus_tag="KNP54_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBF0893846.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVNVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVVVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         8196 a         2409 c         4087 g         7056 t
ORIGIN      
        1 gtcaaaataa taaaagacct tataagttaa ttacaggtta aaaaaataat atgtgaattt
       61 tctgatattt actaattatg aataaaatat ttaagtatta atgtttttag tgagacttta
      121 agacagataa tctcctatta aagatactat atcttagata aaataaatta aaacaatata
      181 aaaacataac aagattacag aaagaaagct cacaataaaa tgctgaaaaa tttattttaa
      241 ggaggaataa agtatgaagt ttcaagaaat gattaatagc ccaggtcttt ggattgtttc
      301 tagtttttta gtaattattt cagttgttca agcaatcgta tttatgaaag aggcactaaa
      361 agaggcttca aatcttggta ttgaaaagaa aggaattaaa gcagcaattc gctcagctag
      421 tgttacagcc attggacctt ctctatctcc tgttattaca ttattatcac tggtagctgt
      481 gattggcgct cctacgactt ggatgaggct ctgtgatgtc ggagcagcta gaacagagct
      541 tggagtaata tctcttacat ccaatttatc tggggtagaa gtaggtagtg ctgcatttgg
      601 agcagaagct ttttcgtatg cactatgggg gatggcttta aataacttag gttggctatt
      661 tgttgtattt attttgggtc atagaatgcg tggaattgtt gaaaagatga acatgaagta
      721 taatcctact tgggttaaaa aactacttgc aggtgctaca gttggattat ttgcttacct
      781 tctttcaaat caaataaaaa catttgaaat accaaaactt acaccagcaa ttatttcagc
      841 tatagttatg ctagtattga caactttatt taaaaagaat caacgattac aagaattatc
      901 cttaggtatt gccatgttaa ttggtatgtt tggtacacag attatattat cgtgattaaa
      961 acggataaga ggtgataatt atgtatgata aaaagatgat aaaaataggg agaatttcta
     1021 taggtcttgc aattattgca aactttattc ccgctatcta tgtaggtatt cgctttggtc
     1081 agatgccaat gctttctgtt atatttcaaa tttgggggtt agtcgctgcg acttatgggg
     1141 ttagttggat tgttcaacct atagcttatt atcctacact aggagctcca ggttcttata
     1201 taggttggct tgcaggttct gttggagata tacgtatgcc tgcagcatca atggcacaga
     1261 aaattgcagg tgtagaagca ggaactcatg agggtgaagt tgttggaaca attggtacat
     1321 gttgttcaat ctttgtatca gcttctatga ttaccatttt taccattgta ggctataaag
     1381 taattccttt gttacctgaa tttgttacta attcatttaa ttatatactt ccagcattat
     1441 ttggagcaat ttatgttgat attgcacgta aggatattcg agctggtgga tgtacgattg
     1501 ctgtagcgtt agcaattatg tactttggtg aaaaaattgg tataccaggt ggattattaa
     1561 cattgtttat tgtgttaggt gggatactta tcacaagggt cttctttgta attgataaca
     1621 ataaaacaaa agaataggat tgcttattaa ggagaaagac tagaattatt tgttgagaaa
     1681 aagaatagga ttgtttatta aggagaaaga ctagaattat ttgttgagaa aaaagaatag
     1741 gattgtttat taagaaatat gaatataaat aagtcttgaa aggagaaaaa gcatgtttga
     1801 tgttaaaatt gtcaatggaa taatcgttga tggtacagga aattcaagat ataaaagtga
     1861 tgtagggatt gtaggagaca aaatcatggc tattggagat ttaagtcaaa aagaggctaa
     1921 agagactata gacgcaactg gaaaatttgt atcacctggt tttatagatt tccatactca
     1981 ttctgattta tctcttgtgt atgataaata cacaagaagc cgtatccata caggtgtaac
     2041 aacagatgtt attgcaaact gtggtatagg agttgctccg ataagagaag agaagaagca
     2101 agagttaatt gattatcttg gaactaggat aattggtaca attccaacaa aattagagct
     2161 tcattggaat acaatgcaag aatactttga ttacttaact gaaaattctc cagcagtcaa
     2221 tgttgtagct tatgtagcac aaggacctgt acgtatcaat gaaatgggat tttcaaagga
     2281 accagctact ttagagcaac ttaaaaatat gaagttggaa gttagaaaag ctatggaagc
     2341 tggatgtgta gctctttcat caggattagt ttatttacca ggagcataca caaagaaaga
     2401 agaaatggct gaattatgta aggaattgat accatacaat ggatactata tatctcatat
     2461 tagagatgaa ggtgatgaag aaatggaagc tcttgatgaa gcaatttata tagctaagac
     2521 tgcaggagtt cctctacata tttctcattt aaaagttatg ggtcataaga attttggaac
     2581 tattgatgag gtatttaaaa agctagatga agctgaggca gatggtttgg aagtaacttt
     2641 tgattgttac ccatatacag ctggaatgac atctttgggt gcacttttac ctccttgggc
     2701 ttttgaaggc ggtgtagaaa atatggtaaa acgattagaa gtacaagaaa atagagacag
     2761 aattataaaa gagttggagg aagggattcc tggatggcaa tgtttctacc aattagcagg
     2821 tgggtggaac ggtgttgtac tagcctctgt aatgactgaa gcaaataaat atgtagaggg
     2881 taaaacttta atggaggtag ccaaaatcaa tggtgaaaat ccatttgata cgttctttag
     2941 gcttttgatt gaagaaaaaa gtaaaattca agtagttgtt catacacaag gtcaagagga
     3001 tacagataag gttgtttgcc atccaaagtc atgtataggt tctgatagta tggacctttc
     3061 tacagaaggt ttactttctc ttggaaagcc tcatcctcgt gcatttggta cttttggacg
     3121 aattttctct tactatgtta gagaaaaagg tatgttgact tttgaggaag cagttaaaaa
     3181 gataacttat ctttcagcaa aacgcttagg catttataaa gaaaggggtc tacttaaaga
     3241 aaattatttt gctgacattg tggtatttga cccagataca atagaagata aagcgactta
     3301 tagtaatcct aaacagtata cagtgggagt ggaatatgtg ttggtgaatg gtaaaattgc
     3361 attggcagga ggaaagcaaa ctgatgtatg tgctggacgt gtaattaaaa atcctcttag
     3421 catagcaaaa tagaatacat taagaacttt tataaaaata gtctttcttt gaatattaag
     3481 gaaggctatt tttgttaaat taataaagat tactctactt gtgttttcta aagaatttaa
     3541 ctttaagtag aaaaaacaat atattaattg taaaatgtaa ttaatattaa tgaataagat
     3601 ttaaatacaa aaatttaaat acaaaaatgt ttcaacagat agtcgtaatt aaaaaactta
     3661 aagtaacttt ttatattagg tataattgat tattcaaaat tctatgaatc aggagtcctg
     3721 tggctttagt catggtaggt ttagaaaatg ttttaagaga taatagtatc attaggaaag
     3781 gagagacgaa atgaaaatac tttatgtagg accaggtatg gtaatcgata aaatactagc
     3841 agtaagtaaa aagaattttc ctaatattga agcagatttt cttagatatg atagatatat
     3901 tgaagtacct gatttattgg aaaaatatag aggtagagtg gatgcagttc tttttacagg
     3961 taagtcgcca tttaaatttt ttgaaaaaag acaaaaagat tttgtattgt ctgattatat
     4021 tcctagacat gaaacaacat tgtacagagt gttgcttgaa attacatatt tgcttaaatt
     4081 cgatattagt agacttagta tagatactta tgataaggct atgatgaaga gattgtataa
     4141 agaaattgga gttgaattta aggatgaaca tatgtttttt gcagagcaaa agtatttaga
     4201 agaggactat ataaagtttg tgcttgaatt tcataaatat aattatcaaa ataatgatgt
     4261 atgttgttgt attacaggtc ttgaagaggc ctatcatata atgaaaaaag ataatattcc
     4321 agtagtttta gccttgcctt ctgaggacgt aatggtgcaa agtataaaaa acattcagat
     4381 gcgttatatt gcaaagaaaa acaatgagaa tcagattatt gttcttgcta ttaaactgaa
     4441 catgccttca gaatattcac taatgaagga agatgagtac gcttatcttt cacaaaggat
     4501 taagattctt gataaactat accatttcaa tagccgtata gatggtgttt tggtagagca
     4561 gagtagaagt gaatttatga tttttacaac taaaaaaata cttgagttag aaacaaagaa
     4621 atacagagat atttatttgt tggatatgat tcgtgaagtt tcagttataa acacttatat
     4681 aggaattggt tatggaaaaa cagcaaatga agctaaattt aacgcttatg agagtattaa
     4741 gatggctcaa agtcaaaaaa atgatgcagc atatgtagtt tttgaaaatg gagaaattat
     4801 gggaccacta aagccaaatc ctactgtcaa agagaaaaat agttttgatg aacgttttta
     4861 tcaaattgct acagagacag ggctaagtgc taatactgta tataaagtat tcaataaaat
     4921 aataaatagt ggaaaaactg aatttacatc aaaggaatta gctactatat gtggtgtaag
     4981 tattagaact atggacagga ttatacttag attgtgtgat tctggttatt gtgaggtagt
     5041 gagtgaacag cttatgagca agtatggtag acccagtaga atattacgtt ttaaaccttt
     5101 tctgttgttt taaatagata taagtcaaaa attaaatttt tatgataaca ttttctttac
     5161 aattttttag atatatgtta atatttagaa aaatgcatat gtattcataa aataaactta
     5221 aaacagctaa aaaatcatta aaaaggaaat cgtatgcatg aaatgagaaa gttaatttat
     5281 aacttaaata aatctgggag gagataatta tgggaaaata tcaggattca aaaaaagttg
     5341 taagaaatta ttttgaagca ttagaaaatg ctactgggga tgaggttgaa aatgtcttaa
     5401 agcaacatat gaaatcagat tataactgga aaggtgtgta tccatttcgt gaacaagaag
     5461 gcactgaaaa tgtagcagat gtattttgga agcctttaaa aaaatcattg agtaatatgc
     5521 aaagacgaca agatattttc attgcaggaa caaatgagat tgacaatagt gaatgggtaa
     5581 tgagtatggg gcattttatg ggactttttg ataacgattg gcttggcatt aaacatactc
     5641 gtaaaatgat tagtttaaga tatgcagaat ttaactgtgt tcaagatggt aaaattgcta
     5701 aaactggatt atttgtagat ataattgggt ttatgattca agcaggagtt aatccattgc
     5761 caccacaaac aggttcatat tttgtatatc cagggccaat tgaccataat ggattacttt
     5821 ttgaagatgc agatgaagtt gaaggagtaa aaactttagc attagtaaat aaaatggtag
     5881 atgatttatc tgaactaaat gaaagtggtg ctatgggatg cccaccagaa atacttgaaa
     5941 aatcttgggc taaagatatg atttggtatg gtccaggtgg aattggtgct tcttatacta
     6001 tacctagata tcaagagcaa caccagctac catttagaaa taatttaaaa ggaaagactt
     6061 ttaatgggca tgtatgtaga tttgcagaag gtaattttgc ttgtttcttt ggatggccta
     6121 atctgactaa tgtaccatgt ggaggttttt taggattacc aggtggagag gttaaagcag
     6181 atatgcaagt tgttgatgtt tattatcgta agggcgataa acttcaagaa aactgggtgt
     6241 taattgatat tccttattgg ttgaaacaac aagggcttga tattcttgag agaactaaaa
     6301 gtatttttaa tgcttagtta tgcatacgta ttctaaaaca aagggggata taaagtggca
     6361 tctaccaaca aaaataatgc aacaagtaaa gaggaagaaa aagaagtttc tacaagtggg
     6421 cttgaatcat gtacggttaa agaaaacaaa gctaaaatga atcaaactaa ttttagtaat
     6481 ataaatgaaa atcaaacaaa tgagaataaa acgaacacat ataaaagaaa tatagataaa
     6541 ggaaatatag ataaagggaa tatagataaa acaaacacaa ataaatccga cataaataaa
     6601 gttaacatag atacagtgga tacagataaa ttaaatacaa atactcttac tgaaaaaaat
     6661 aaaaaagtta tatttaaggg ggaagataat atgtcatcta caaaaattta ctatggagat
     6721 tcattagaag taacgcctgt tggagtaatg gattacaatg atttttcaaa acagacaaaa
     6781 agggaacagg aaatacctgg atttgattct aagtatagag attttgtaga ttatattatg
     6841 aagattacac ataatatctg ggaagaaaaa ggtataggtg ttatttatga tacatatcac
     6901 aataatgtta caatgcattg tggctcttca aatttagttg gtattaaaga tgttatttcc
     6961 aatactcttc aaacattaca tgcgtttcct gatagaagat taattggtca aaatgtaata
     7021 tggtctaact ttggtgctga tggtttttta tcttctcacc gtgttttgtc tacagcaact
     7081 aacttaggtg atagtaattt tggaccagca acaggtagaa aaataaactt tagaactgta
     7141 attgattgtg ccacaactaa caatagaatc catgaagaat ggttggttag agataattta
     7201 tggattgtta ctcaattagg attaaaccct caggaagtag caaagagtat ggcaaaggca
     7261 agtgaatcta aagtgcttag tttacaatca acttatggta tctgtgaatc tatggatggt
     7321 caatttatgc caactaagta tcaagcaaaa gatgattctg ttggcgaaat gatgcttgaa
     7381 atgacaagcc gtatttataa ttataaatat ataaatgaag ttaaaaaata ctatcatgat
     7441 aatgcagtag tacattttat atgtgataaa gatttaaatg gctatgatga gattcaagga
     7501 atgattgtaa gtttatttgc atcaattcca aatggaagtt atgaagtgga aagagtaact
     7561 tgtaatcaaa gagaaaaaaa tgaaggttat gatgtatctg taagatggag attacgtgga
     7621 ataaatgaag gtataggatt ttttggacag ccttctggaa agcatataga agtaatggga
     7681 atcaatcatt atcatatact acaaggtaaa gtaaaggagg agtggataac ttttgatggt
     7741 atggatgtat taaaacaaat ttatatggga gtagaagaat aaagctgttt agagtataaa
     7801 tagttttgaa atatataggg aagtattgct ttataaaatt taagtgggga atgtatatga
     7861 aaaatagatg tttaaacttt tagcaaaatt atgactaaat ttaaaagggg gaattataaa
     7921 aatatgaaaa caacggttga aatagaaaat gatatcatat taggaaaaga ctattcaaac
     7981 ctaaaaagag gaattgcatt tttttcaatt gctttaatat acttttttta ttgctacaat
     8041 tttatggtgg gtacttttat taaaccaaca atgatttatg ctttagcaga tgggggattt
     8101 ggtttttcat taaaacaaac agaagaaata tttgcagtta tgtcttttgg tacaattcca
     8161 ggtacattta tttttggggt gatttctaca aaaattggga agaagaggac tttaattagc
     8221 gttgctttac tgattggatt gacaacattt ataccaatgt tatctcctac aaatattatg
     8281 ttatggaaaa tagcacgttt gtgtacagga gtagtgttgg gaggcgtatt tggaacagct
     8341 atgcctttag ttgcagatat gtttccaagt aaatatcgtg gtaagttagc tgctatatta
     8401 actgctttat tttcattagc aatgattttt ggtgggaaag tatatggcgt tttaggtgat
     8461 gcaaattggc aaatattgat gtatactgcg attataccac ctatagttgg agctatctta
     8521 gcaatcttct ttgtgccaga tgatttggag tatacaaagg aattagttaa aaagggaaaa
     8581 gaaactggtg aaaagattag ctatataagt atgtataagg gaaaatactt atggattgga
     8641 ttgggaacga ttcttttatc aggtgcaaat tttacagcat attcagcatt ttcaaataat
     8701 gcaactacat acctagtgac aggaatagga atgtcagcag cagtggctga gtctatatat
     8761 agtttacaag gaattggtca attagtagga tatttattct ggggttcaat tgcagataaa
     8821 tttggaagaa aaataccttt tataggtatg gcattagcag cagtatttgt ttttatatat
     8881 acaaaattag gtggagataa tacaacaaca ttctatatga tatcagtatt actaggtgtt
     8941 gctgttggat attctggagc atggggagca tactacacag agttgttccc aagtaaatat
     9001 cgttcgttgt catctggtat gtcatttaat ggaggaagga ttatatctac gtttgcaata
     9061 cctgctatag ctggtacagc ttctggtact ttaggtatga tgactatctt ttacatatca
     9121 atcgcagtct ttgtagcagg tgctattgta tggttattct taccagagac gttaaataat
     9181 aaaaaataaa atactaggaa tttattttgt tacttagaaa ggggtggctt atgatttcat
     9241 caattgatgt atgtattata ataggatatt tgctattaat gttagttatt ggttattatt
     9301 caggaaaaga taataaaaat caagaagatt atttcttggc aggtaggtca atgccatgga
     9361 ttccaattgc tttatcagtt gcagctacta tgattagtgc aaatggcttt ataggtggtc
     9421 ctggatgggc atatgtagat ggaatgtatc cagtaatggt taatattaca gtacctttag
     9481 caatattttt tgcactgagc attaccaccc cagttatcta taaattaaaa ataacctcta
     9541 tatatgaata tatgggactt cgtttaggaa attattcaag aggattaact attattcaat
     9601 tttttattaa ttcattgatt caagctagtt ctatggtata tattccagtg cttattattc
     9661 aaatgattac tggctggtca ctttatgctt tagtcccaat agttgtactt gtatcaatta
     9721 tatacactct attaggtggg attaaggcag ttatatggac tgatagtatt caaatgatag
     9781 tagtaataag tgctgtattt atagtaatta ttgtagcctt aaaaggaatg aatctaagtt
     9841 tctttgatac attacaaatt gcacaacaga gtggaaaatt aaatacattt gatttcagta
     9901 gggatatttc agtgacaaat actttttggg ctactttaat tggtggaact gtaatgtgga
     9961 taagatactt ttgttttgac caatctcaag tacaaagagt tttaacatct aaatctttaa
    10021 aatgtgcaaa aaattctttt gtagttagtg catttgttat gaatttagtt tactacttta
    10081 tgctattggt aggagtaatt ttatttgttt tttatggggg aaggacattt gaaacttcaa
    10141 atgaaataat gattactttt attttaaatg aacttccagt aggagccatt ggaattatta
    10201 ttgcaggtgt gtttgcagca gcaatgtcta gtatcgactc tatattaaac agtatgacaa
    10261 ctgtttttac gaaggatatt tatgagtttt atttcaaaaa agataacaaa gaatcatcat
    10321 taaaagttac aatgattata actgtagtta taggagttgt tatgacaggt tttattatta
    10381 tgggatttgg aggaagcatc aaatcaattc ttgaccttgt tggtaactat atctcatact
    10441 ttgctggacc agctacaggt gcatttgtac tagcaatgtt tacatataaa gctaatgata
    10501 aaggagtatc tattggtttt attgtagggt tagttttagg attttttatt tctaataaat
    10561 ataatgtgag ttggttgtgg aatccagcaa taggtgctac aataacattg atatttggat
    10621 atatttttag tgtcatttta aagaaaaatc ataatgcaga tgatattaaa aaatacactg
    10681 catttggtat gagaaatcac cttatttctc aaggaatgga taaagtagat ggagtatcta
    10741 tagtgccatt ttctttaggt aaacaagaat taattgtatt agcttttttt attatccaat
    10801 atattatatt atttttgata caattttaag aagaaatact agatatttaa ggagaaatac
    10861 taaatgaatc aaaagaaagt tcattataat aaatcggcta cctcaaaaga tgttgcaaga
    10921 ttggcaggag tatctcaatc atctgtttca agagcatttg gtagtgcaaa tggaaagggc
    10981 gtaaaacctg aagtaagaga aagaattttt cgtgtagcaa atgaaatagg atatgttcct
    11041 aatttggtag cacggggaat gattagtgga aaaactaatg ttataggatt gatagttggt
    11101 gatagtctag gtccatttta caatagaatt atcaatttat ttgtagaaaa aattcaagag
    11161 ataggtaaac agtgtctcgt ttttaaagtt cctagacaac aaagtataga tagtataatt
    11221 tcaaaagtaa ttcagtttca agtagaagct gtgattatta cagcttcggc catgaataag
    11281 gtgatggctg agacttgtga agaaaacaat attcctgtga ttctttttaa tcgttttata
    11341 cctggtataa aaataagtac agtctatgta gacccaattg aaggtggggg aatggctgct
    11401 gaatatctgc ttaagaaagg tcataagaat ataggatata ttcaatttac gagagaaaca
    11461 agtgaagaaa tggaaaagaa aattggattt tactctaagt taagacaaag tgggattcat
    11521 aaccttaaag aagaatctgc aaactatgat tatgattctg gatatgaagc aggtaagaga
    11581 atgttagcat tatcaaatcc tccaacagca attttttgca caagtgactt gatagctatt
    11641 ggtgtaatgg atgctgcaag gtttgagtac aagttgaggg tgccagagga tttatcagtg
    11701 ataggatatg atgatattca aatggcttca tggaagagtt ataatttaac gacgattaga
    11761 cagccactag atttgttgat tgaaaaaaca attaacatac ttaagtcctt attaaatgaa
    11821 gaaaatccag agtcagtcgt tgaaatgtta aaacctgaat tgattgaaag aggttctaca
    11881 ctttaagtgg tagatattta attaagtggt agatatttaa ttaagtggta gatatttaat
    11941 taaatggcag atatttaatc aagtgataga tacctaatta agtgatagat atttaatcaa
    12001 gtgatagata cctaattaag ttgtagatat ctgataagaa atttttaagt tttcaatcgt
    12061 tctaaattgt gagtataaaa atctactaaa tttagttatg taaaatataa attataagtg
    12121 tagaaactag gctactagct tttataccac ttcaaacatt actggaggta gttaagttta
    12181 cagcagttta gttttatgta gatataatat tctgtaaata gacaaaatta aaatatgtaa
    12241 ttaaaatatg taagtgtctc aaaatgaaat ttttagttta tgaggcactt ttttgtataa
    12301 aatcaaatgt atttttataa ctttaacaat aaaaagaggc ttatctctat tttgagacag
    12361 cctcaaattt ttaaaactat attagtttac agcttctttt cctatcaaat cttttaactc
    12421 ttcatgagtc atagtttctt tttcaaataa gaatttagaa acagaatgta aatcttcaag
    12481 attatccttt aacatctcta aagtctcttt ataacaaatt tcaactatac gatttgcttc
    12541 cttttgaacc ttatcacata agaaagtctt atcatttcca tcaatagtca taaatcctaa
    12601 gttactcata ccatattcac aaaccatttg gttagctatt tcagtgactt tctttaagtc
    12661 gtcctttgca ccagtagatt tatgattaaa tattaattct tctgaagcct ttccagcaag
    12721 taatattttt atttttccaa tcaactcatc cttagtataa atatatctat cttcatcagg
    12781 taattgaaga acataaccta atgcttgtcc tctaggaact atagatattt tttgtatagg
    12841 acaaattcct actatatcac ttacaagagc atgtccagct tcatgatatg ctactatttt
    12901 tttctctttt tcaaccaatg cagagttttt agattctagc cctgcaataa ctctttcaag
    12961 tgccttgtca aaatgttctg atgtaataca ctcactgtca tctctaactg caaatatagc
    13021 tgcttcattt gctatatttg aaagatgagc cccattgaaa ccatgagttt ttttagctaa
    13081 aagttctaga tttacagatt tgtctatagg tttgtcatct gtatgtacct ttagaatttc
    13141 aaatctagtg tgatagtttg gtgcacctat atgaatgtgt ctgtcaaatc ttcctggtct
    13201 aagtaaagct tcatctaata agtcaagtct attggtagca cctattatta atacattgga
    13261 atctttatta aatccatcca tttcaactaa aagttggttt agtgtttggt ctttttcgtt
    13321 gttactttca agatgtctct ttgctcctac agcatctatt tcgtctataa atattatact
    13381 tggagcttct tttctagctt tttcaaatag agttctaact ctttttgctc ccacacctac
    13441 atatttttca acgaactctg aaccagtaac attgaaaaat gatgagtttg tttcaccagc
    13501 tacagcagat gcaagtaggg ttttacctgt tcctggagga ccataaaata atactccttt
    13561 aggtattttt gcacccattt tttgatattt ttgtggtgac ttcataaaat cgactatttc
    13621 aaatagttct tcttttactt cgtctaatcc agcaacgtct ctaaatgtag tctttggttt
    13681 tgtagaaagt gaatcatctg tttgattatc tctttccatt tttgtctgtg caaagacagg
    13741 agctggattg ttgattttct taaaaaagtt gtttagcatt ttcatattca cacctcaggt
    13801 aattaattat tgttaatcaa ttttatattt tccatattta ctatttttta ttatttattt
    13861 ttcatggaaa aaatatacat gttatctaaa taaaaataaa tttgtaagat gtatgaaaaa
    13921 atgaatttat gtatatagag atttctactt atgtattgaa taaagtatta caaattataa
    13981 attatgtatt gattatatat tgagtaaagt attataaagc atgtattgat taagtattta
    14041 ttaagtattg aataaaatat tacaaattta gttgaaatga aaatgataaa aaatgttgta
    14101 ctatatttta caaatcatat aaatagagaa attgttgtag cgcaaagtag taggtagtat
    14161 attagaatat aattatagga tttgttgtgt agtatagtag catattagaa tataatatag
    14221 gatttgttat gtagtatagt agcatattag aatataatat aggatttgtt atgtagtata
    14281 gtagcatatt agaatataat ataggatttg ttatgtagta tagtagcata ttagaatata
    14341 atgtaggact tgttatgtag tatagtaaca tattagaata taatgtagga tttgttatgt
    14401 agtatagtag catattagaa tataatgtag gacttgttat gtagtatagt aacatattag
    14461 aatataatgt aggatttgtt atgtagtata atagtatatt agagtacaat atagaatttg
    14521 ttatgtagta tagtagtata ttagaataca atatagaatt tgttgggtag tatagtgtta
    14581 tattagaata caatatagga tttgttatgt agaatatata gagtcatgta gaatatacat
    14641 atataaaagg attttgggta taaatttaaa aattaatagc aaaatgagta gtatagacat
    14701 ataattagta gtaggaagta attaaatttt tcctaaacaa aaaaaatagt tgcaaataat
    14761 ttgattaagt gatatagtaa ataaggtaag aataaaacaa agaagaagtc cgcttctcac
    14821 cttacgccgg aggttagtaa ggtaaatata agttaaagct taattttaat ttaagtttgt
    14881 ttaaatttgg taacttatat tgcggatgat tacgtcatcc gctttttatt ttataaaaat
    14941 tttggaggtg tcctacaatt agcaaagaat tagcaatcaa tgaacaaata aaagataagg
    15001 aaataagagt cctttcacca acaggtgaac aacttggagt aatgcctact aaagaagctc
    15061 aagcaatggc taatagcaaa aacttagatt tggttcaaat ctcgccgaat gcaaatccac
    15121 cagtatgtaa gataatggat tatggaaagt ttagatatga gcaagcgaga aaagagaaag
    15181 aagctaagaa aaaacaaaaa actatagttg taaaagaagt aagacttaga ccaggtattg
    15241 aacaaaatga tttaaatacg aaagctaata atgctataaa gttccttaaa aaaggggata
    15301 aagtcaaagt tgaacttaga tttagaggaa gagaattagg acataaagac ataggtaaag
    15361 aagttatgct taagttttta gatataataa aagagtttgg agaaccaaca aaagcccctg
    15421 catttgaggg taataatatg gttgtaatta tagatccaaa aaaatagatg attaactgag
    15481 aggaggaatt tgtcatgcct aaaatgaaaa ctcatagagg tgcagcaaag agattaaaga
    15541 aaacaggaac tggaaagtta aagagagcta aagcttttaa aaaacatata ttaactaaaa
    15601 aatctgcaaa aactaaaatg aacttaagaa aatcaacttt agtaagtgat ggagatgcta
    15661 agagaatagc acaattatta ccatactaag atacagattg taaataataa ctatagaaga
    15721 gggatataaa aggaggtcat aacgatggca agagttaaaa aagctatgaa cgctcgtaaa
    15781 aagcataaga aaatattaaa acttgcaaaa ggattcagag gatctagaag caaattatat
    15841 agaccagcaa atacattcgt aatgaaagca ttaaaaaatg cttatatagg aagaaagtta
    15901 aagaagagag acttcagaaa actttggata caaagaataa atgcagctgc tagaatgaat
    15961 ggaatatctt attcaagatt aatgaatgga ttaaaattat ctggtgttga agttaacaga
    16021 aaaatgttat ctgaaatggc tatacaagac ccagaaggat ttgcaaaatt agcagaagtt
    16081 gctaaagcaa aattagctta gtattgaatc atgagatgta aagtctttga gttatataaa
    16141 taattcaagg acttttttat tttttgaaaa atacttatta gtgtcatgta caaccaattt
    16201 tataatgata aataaaataa gcaatacaat agaattttat gagatttatt ataagaattg
    16261 ttacaattat ttatgatagc tataaaaagt catagtaaaa atgatattga tgtatgttga
    16321 tatatgtata aagtttccaa tcaatcttga attaatatta tcaacatgat aatattatct
    16381 tattaataat ataaataagg gggacataat atgaatgaaa aactaatgga ttgttttgta
    16441 aacccaatta aatgcaagtt attgattgaa attttttcaa ataatcgaac tacagctaaa
    16501 caattaggag aaaaatttca agatatatca aaggcaacac tttatcgtta ccttaataaa
    16561 atgttgaaag atgatattat aaaagtggtt gaagaaaata aaataagggg aactgttgaa
    16621 aaagtatatg ctatgaagtt agatatagct gatgatgtga acaaaattat agatgagaac
    16681 tctggagaag aatatgctca actgtttact caatatatga tgggattttt aagagaattt
    16741 tatgaatacg ctgaaagaaa ggaaaaggat atcctaaaag atggttcagg attttctgtc
    16801 tgtccagtat atgctagtat tgatgagata gttgaagtga gtaaaaaaat tgctagtata
    16861 ctagaacctc taagaaataa ctcacatgaa gaaggtagaa gaatgcattc tataggagtg
    16921 ataattactc cacctaaaaa ggatgaaggg aaataaatct gatttacatg gggtagagcc
    16981 aatttataca gggaatcgtt ttatgattta catatgtatc cagagcaaag tatctctgct
    17041 tggattgtac ttcattgtac catttcatcc aatgacttgg agtggtacaa tgaagttttt
    17101 taatttttca tattaatgct aaagaaatga actttagacc acatatgcaa ttaggttgca
    17161 ttatacaatt agaccacata tacaaaataa aaatcagtat ttttatagca gataaattga
    17221 ctgtcattct tcttaaaaat catctattag ttattgttag catattgaaa gaaattatag
    17281 taatctattg aataaatgaa tattgcctat aatcatataa actgctatag tttaaaataa
    17341 agcaggacgt taaattttat agtaatctaa aaatttaaga gggggatttt atgaaaataa
    17401 aatttgttat tatgccattg gtgatatttt taatggtatt atttgtgggg tgtcaaagta
    17461 caaaagatac agaagttaaa gcaaaagata cagaaattaa aatattaggg acaggtgatt
    17521 tacattcaat tttgacagac tctatggttt cgtatgtaaa tgaggaaagg gaaaagaata
    17581 aaaatctgct tatggtagat gcgggagatt tctatggtac acaaagtaga gaaatgtggg
    17641 aatggtcttc tggaaaaaag ttaattaata ttaaaagaaa tggtagagca gagtatgatg
    17701 acataattaa gagtagtaaa gatgaagtac ctatagttaa agatatggca aagttgaaat
    17761 atgatgctgt agttttggga gataatgaat ttgtttcaaa tgataagcaa agtcttgata
    17821 aactggtttc tgattttaaa aataataata tgccattggt atcagcaaat atatatgaac
    17881 aatctggaga aaattatgta caaccatatg taatgaaaaa tattaagaca gatgagggca
    17941 atgtaaaagt tggaatacta ggtcttacta taaaagaagt aggggaaacc cttggtcttg
    18001 aggattttga aaaggataaa aaagctagag agcttggaga acaagctgat tacaaaggaa
    18061 aattatatgc aaatgattta gtagaagatg caaaaaaatg gataaaagtt atggaaaaag
    18121 aaagtccaga cataatagtt gcagttgtac actcagggga agaacctaaa acagatagaa
    18181 atccaggaaa tagaataaaa gagttagcaa ctacagtgga tggaatagat gcaattgtag
    18241 ctggtcatac tcatgaaaaa atagatgaac acaaatataa aaataaatct ggagatgaag
    18301 taattgttac acaaccaggt tggcatggag atagagtatc agagattaat ttcaaactaa
    18361 ataaagagaa tggaaagtgg gacataaagg aaaagtctag taaattaaaa ataattgata
    18421 aagaagtaag tatagttgct actgcagatt tacattcaca tttctctgat aaattaacag
    18481 ttgaccttgt taatgaacga agtaacccaa ttgaacctgt tgtagtagat gcaggcgact
    18541 tcttagaccc tcaaacagat gaaatgactc aatggtataa agagtggaaa agtataagag
    18601 ataataatag tgataaaacg attagtagat gcccaatggt catggatatg aatcagggaa
    18661 tgtatgatgc agtagtactt ggaaatcatg aatttgtatc tgaaaaagat gaattttggt
    18721 cagatgaacg ccttttagat gctgttatag aggattttga acaggtggca atttctgtgt
    18781 tatcggcaaa tatatatagg caatctggta aaaattatgt taaaccatat attataaaag
    18841 atgtggagac gagtgaaggt aatgtaaaag taggaatatt gggacttact ataaaagaag
    18901 taggtaaagg tcttaaaaat gtaaacttac aagagcaatt tcaatataag gataaattgt
    18961 atgcaaatga tttagtggaa gatgcaaaga aatgggtaaa agttatgaaa aagaaaaaac
    19021 cagatataat agttgcagtt gtacattcag gagaagaacc aaaaaatcca aaacatccag
    19081 gaaatagaat aaaagaacta gcaactacag tagatggtat tgatgcaatt gttgctagtc
    19141 atactcatga aaaaatagat gagcatgaat ataaaaataa gtctggagaa aaagttatag
    19201 tgacacaacc aggtgagcat ggtaaatatt attctaaaat tacctttaaa gtaaataaag
    19261 aaaagggttc gtggactatt aatgataaat tcagtaaaac aattgaggtt gaataacttt
    19321 ataaaattta tagataaagt aaattatctg atattggcat gatatataag ataaagtttc
    19381 taatattagt ataatgcata atgtgaaata ttttaataat aagagaataa acaagacaaa
    19441 taaaaatatt ttaacatgta agatatagta tgaactatta tactaatgct tactttataa
    19501 tttgaacatg ttagaataag tcttatttga aaattttagt gtactagagt aagtattatt
    19561 ttactagtaa aaaatattga gaactatatg tagatttgct taaaaaggaa tttacatata
    19621 gttcttttcg tataataaat agtacaatct tatatggtaa agataaagtg tgatattaaa
    19681 ttttattatc atccaaaatc taaggaggag tctcttatga aaataaaatt tattatagta
    19741 gcatcaataa tatttttaat agtattactt gtggggtgtc aaagtactaa agacacagaa
    19801 atcaatgtac tcgccacaag tgatttacat tcaattattc cagataattt aatttcctat
    19861 gtagaagagg agagaaaata tgatgagaat ctacttatgg tagatgcagg agattttttt
    19921 gacatgcaaa gtggtgagat gaataagtgg tttactggtc aaaaattagt aagatttaaa
    19981 gatgggatac cagagtacaa aaaaatagct gaaccacgtg aaggagaagt tccattggct
    20041 aaaaaaatgg caaagctgaa gtatgatgca gttacatttg ggaatcatga atttgtatct
    20101 aatgacaagc agagccttga taaattggtt tctgatttta aaaataacaa tataccatta
    20161 gtatcagcaa acgtatatga acaatctgga gaaaactacg taaagccata tgtaatgaaa
    20221 aatataaata ctgacaaggg aactgtaaag gttggtatac ttggtctgac tataaaagaa
    20281 gtaggggaac gttcaaggtt taaaagtttt gaacaagata aaaaggctag agaacttggg
    20341 gaacaacctc aatacaaagg gaaattatat gcaaatgatt tagtagaaga tgcaaataag
    20401 tgggtaaatg ttatggaaaa aaaagaaaag ccagatataa tagttgccat tgtacattca
    20461 ggtgaagagc caaaaaatcc taaaaatcca ggaaatagaa taaaagaact agcaacaact
    20521 gtagagggaa tagatgctat tgtagcaggt catacacatg aaaaaataga acagcataca
    20581 tataaaaata attctggtga agaagtaata gtaacacagc ctggagctca tggtaatagt
    20641 atatcaaaga ttaattttaa gttggataag aagaatgata agtggtttat aaaagacaaa
    20701 tatagtgaat taaaggtttt tggaaaggaa gtaaatataa ttacaacttc tggtctgaat
    20761 ccaaaatttt cagatgaaat ggcagttaat ttgtttaatg aaagagatag agatgttcaa
    20821 cctatcttta tagatactgg agatttttta aatactaata caaaagaaat gactaagtgg
    20881 gctaaagagt ggcaatacaa tgaaaataaa ggcatctata aaaaaataaa tgaatggcca
    20941 attgtatatc ttggttatga tgctgtagta cttggtagcc atgaatttac agaggataaa
    21001 gagacttttg aggaaaaaaa atctacattg gattatatta tagaaaactt tgaagaaatg
    21061 aagataccag tattatcagc taatatatat gatgaatctg gagaaaatta tgtaaaacct
    21121 tatataattc ataatgtaga aactagggaa ggaaatataa aggttggagt attaggtctt
    21181 actactactg ataaggatga agaagactta agtaactcaa gcttaagcaa agactcaaag
    21241 acttcgaaaa ttcctgaaga aacaggaaag ttatatacta ataatctagt aaaagatgca
    21301 agcgaatggg taaaagttat gcaaaaggaa agtcctgatg tgattgttgt agttgtacat
    21361 tcagataata atagtactct aaaaaatcca agtagtgaag tcaaaaaact tgcaatgtca
    21421 gtagatggaa tagatgctat tgttgtaggt catacgaaaa ataaggtaga agaacatatt
    21481 tacaaaaata agtctgggga tgaggttata gtaacacaat ctggagaaga ttgttattca
    21541 aaaataagtc ttgaactaag aaaagaaaat ggcaagtgga atatcataaa caaatatagt
    21601 aaagcaataa aaatgaagtg aatttattga tatataaacc attattaaca ctgattttta
    21661 taatataata aatactgatt ctacaatata attaacactg atttttataa tataataaat
    21721 actgattcta caatataatt aacactga
//
LOCUS       DAEHWO010000071        21611 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEHWO010000071 DAEHWO010000000
VERSION     DAEHWO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.071"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(400..2004)
                     /locus_tag="KNP54_002978"
     CDS             complement(400..2004)
                     /locus_tag="KNP54_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0893847.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENHIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            2389..3315
                     /locus_tag="KNP54_002979"
     CDS             2389..3315
                     /locus_tag="KNP54_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBF0893848.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(3435..4433)
                     /locus_tag="KNP54_002980"
     CDS             complement(3435..4433)
                     /locus_tag="KNP54_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBF0893849.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            4537..4974
                     /locus_tag="KNP54_002981"
     CDS             4537..4974
                     /locus_tag="KNP54_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0893850.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            5060..5647
                     /locus_tag="KNP54_002982"
     CDS             5060..5647
                     /locus_tag="KNP54_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBF0893851.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(5947..6357)
                     /locus_tag="KNP54_002983"
                     /pseudo
     CDS             complement(5947..6357)
                     /locus_tag="KNP54_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4004 family protein"
     gene            complement(6475..7593)
                     /locus_tag="KNP54_002984"
     CDS             complement(6475..7593)
                     /locus_tag="KNP54_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBF0893852.1"
                     /translation="MAVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKVRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTNVDIEVFENTNNQIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFVRQLKYKANWHGRQIVKVGKFFASSQICNKCGYKNEEMKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            complement(7595..8002)
                     /gene="tnpA"
                     /locus_tag="KNP54_002985"
     CDS             complement(7595..8002)
                     /gene="tnpA"
                     /locus_tag="KNP54_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013824389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBF0893853.1"
                     /translation="MEVTHGRGYVYLVQYHIVWCVKYRHPVLTNEIEEDLINILNKIA
                     EDNKFQILECNSDKDHIHLLINCSPQHYIPDIIKALKGVSARLLMKKHGEQLKKKLWG
                     GHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            complement(8571..8780)
                     /locus_tag="KNP54_002986"
                     /pseudo
     CDS             complement(8571..8780)
                     /locus_tag="KNP54_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4004 family protein"
     gene            complement(8882..9430)
                     /locus_tag="KNP54_002987"
                     /pseudo
     CDS             complement(8882..9430)
                     /locus_tag="KNP54_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9789..11699)
                     /gene="phnW"
                     /locus_tag="KNP54_002988"
     CDS             complement(9789..11699)
                     /gene="phnW"
                     /locus_tag="KNP54_002988"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBF0893854.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(11978..12763)
                     /locus_tag="KNP54_002989"
     CDS             complement(11978..12763)
                     /locus_tag="KNP54_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBF0893855.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(12980..13210)
                     /gene="dltC"
                     /locus_tag="KNP54_002990"
     CDS             complement(12980..13210)
                     /gene="dltC"
                     /locus_tag="KNP54_002990"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBF0893856.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(13229..14377)
                     /gene="dltB"
                     /locus_tag="KNP54_002991"
     CDS             complement(13229..14377)
                     /gene="dltB"
                     /locus_tag="KNP54_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBF0893857.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(14377..15891)
                     /locus_tag="KNP54_002992"
     CDS             complement(14377..15891)
                     /locus_tag="KNP54_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBF0893858.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(16012..17202)
                     /gene="dltD"
                     /locus_tag="KNP54_002993"
     CDS             complement(16012..17202)
                     /gene="dltD"
                     /locus_tag="KNP54_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBF0893859.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(17490..18509)
                     /locus_tag="KNP54_002994"
     CDS             complement(17490..18509)
                     /locus_tag="KNP54_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBF0893860.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(18685..19224)
                     /locus_tag="KNP54_002995"
     CDS             complement(18685..19224)
                     /locus_tag="KNP54_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBF0893861.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(19325..20005)
                     /locus_tag="KNP54_002996"
     CDS             complement(19325..20005)
                     /locus_tag="KNP54_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBF0893862.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(20034..21323)
                     /locus_tag="KNP54_002997"
     CDS             complement(20034..21323)
                     /locus_tag="KNP54_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBF0893863.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT         7081 a         3701 c         2277 g         8552 t
ORIGIN      
        1 aactgcttac aaaaaatact caaagaaaaa tagtaatttt ctcagattca caatatattt
       61 tatatgaaat gttataaggt aatctattta ataaatttaa atttgctatt atagatttag
      121 ttccaaagtc ttactgcaaa gtaatataca tagtttttta ataaactaat aagttcaatt
      181 aataactact taattgttta atatagtaca tagataactt taataaatcg acagttattt
      241 aaaaaggtag aatcaataaa attatactta taaatcttca atacaataat taaaatttaa
      301 taaaaatata attgttgatt taactgtaat cttatttaat tctacctaac ttattatata
      361 aaactatttt ttatagatta taaaatatct aactttcatc tacttcaaag aatacaatac
      421 ttctccttct cttatagtct gcaatacttt aatatctttt attttcatag ggtcgattgt
      481 aagtgggttt tcatctaaga ttatcaaatt agctaatttc ccttctttaa ttgaaccttt
      541 tttatcttct tcaaaatatt gatatgctgc atttatagta acacccttta aagcatctaa
      601 tgggcttatc ttttcatttt ctcctatttg tatacctttt tttgtaattc tattgacagc
      661 acaccatact gtttccagca tattaggtgc tattactggt gtatcctgat gaagagtgta
      721 aattaatccc ttttctatag ttgttttaag tgggctaatc ttaaacgctc tatcttctcc
      781 aaggtttttg atatgaatat caccccaata atatgtgtga gctacaaagt atgaaggtat
      841 catatttatt actttcatat catcaatctg gtcttctctt actgtttgag catgtatcat
      901 aactggtctt atatgatttt cactactttg ctcttttaaa tttaaaactt tctcaaacgc
      961 atctatcaac tggtctgctg ctgcatctcc attacaatga gttaagagtt gcatcttttc
     1021 ttttagtgaa atatctataa acttttctac ttcttcatct ttgtatatag gatatccaca
     1081 ataaccatca tctgaatttt catatggtct actcaaccat gctgtcttac cttgtggaga
     1141 accatctaag aaaatcttat aacctcctat tttaaatcta tttatatatt tttttataaa
     1201 ctccctatta ttatctgcta cagacttact ttttttcaaa tttacatatc ctacaacatc
     1261 catttttaat ttattttgat ttgccattgc ttttaaaatg ttaaattgat tttcttccat
     1321 taaaccttct tgagctgttg taataccata gcttagatat atgttctgtg ctttttcaat
     1381 tgaattaaaa atctcatttg atgatggttg ttttatttta gatgctacat taaaaaatgc
     1441 attttcttct aaatatccat ttggttcttc actgccttct actctaccta tatgtccacc
     1501 ttctgggtca cgtgtttcat tggtaacacc aagctgtttt aaccccaatg tatttgcaac
     1561 tcccatatga ccagaagcat gtgaaattag tattggattt tctgaagatg cactatcgag
     1621 tacactctta tctggatgct tattttcttc taaaaaatta ttatcatatg aaaatccaat
     1681 tatccagtct ccttttttta tattattcga ctctttgaaa tcctgtattt tttttactat
     1741 gtctttaaaa ctggttgcat cttctaaagg aactagcttt agagtagtag caaaagctat
     1801 caagtgacta tgtgaatcta taaaagatgg catcaatgtc ttaccttgta aatctataat
     1861 ttctgtatct ttatttttca aagcaaatac ttcttctttt gttcctatct tttttattat
     1921 tttgtctttt ataagaatag catctccaca tattgaatct tccattgtga tgatatttcc
     1981 attgtaataa attttttctt tcataaaatt ctccttacgt tgtctacttt aataaatttt
     2041 tttcattatt ttctgcttaa ttatattatc ttctttataa actttttctt tagagtttaa
     2101 tcatataaaa gttttatttt taattattgt ttgccaagaa gtaaatacta ttcattgtaa
     2161 ataagacaaa ttaataggct ttatactaat tgaaaaaata ttataagttg ttaaatttaa
     2221 atatctaaac tcaattatat ctgtacaatt gtaatttttt aaatcatgat gtattatttt
     2281 aaatatacag ttacattatt attcacaata taagtatctt agttctcaaa taacatctca
     2341 tgtaatctat tcaatgcaaa aaatttaaat attttttagg aggtttttat gagcaaggaa
     2401 aataaaaatg taagaattgc tgttgtccag gcgtcaccag tcataatgga tttagaaaaa
     2461 actgttgaaa aagcattagg attaattaaa gaagctggta gaaaaggggc aaatatcgta
     2521 gttttccctg aagcattcat acctgcatat ccaagaggtc tttcatttgg atttgttgtt
     2581 ggaagtagaa caatggaagg tagagaagat tggaaaagat actatgataa ttctgtacca
     2641 gttcctagtg ctacaacaga tttattagga aaagcagcac aagaagcagg agtatatcta
     2701 tcaatgggta taacagaaag agatggtaat gatataaatt gtacccttta ttgcacaaac
     2761 ttatttttct ctccagaagg taagctaatt ggtaaacaca gaaaacttaa acctacagga
     2821 acagaaagat gtatttgggg agaaggagat ggaagtactc ttacagtagt tgatactcca
     2881 tatggaaaaa tgggttcgtt gatttgttgg gaaaattata tgccattagc tagaacagct
     2941 ctttatgcta agggtgtaaa actttacata gcccctactg cagattcaag agaagagtgg
     3001 caagcaacta tgaagcatat tgctttagaa ggaagatgtt ttgtaattgg atgcaatcaa
     3061 tatgttgaaa aaaatatgta tccaactgac cttaactact ataaagagct agatgcagaa
     3121 ccagaaatta tgtgtccagg aggaagttgt atagttgacc cttttggaaa atatgtagca
     3181 ggtcctattt tcaataaaga agaaatgcta atagctgatt tagacctaga aaaaatagta
     3241 cttagtagac tagattttga ttcagaaggt cactattcaa gaccagatgt atttgaatta
     3301 attgttcatg aataatcttt ttacacaaac atctacataa atctttttac ataaaaaaat
     3361 gagatactca caagtaaatt tcaagtatct catttttgct taaaacctat aatcctaatt
     3421 ataaatttat tcacctatat tttttctaaa tcaactactg ttcttccaac atgttttcct
     3481 gccattattg aatctatact atcatttaac tcttccaatg atactacatt taccatatca
     3541 tctaaatcat ctaatttcca ttcatttgat aataaatccc atatttttaa tcttaagttc
     3601 attgggcaat ccacagaatc tataccatat aaagtaattc cctttaagat aaatggatat
     3661 actgaacttg taaaatcaac tcctcctgca ttaccacaag ttgttactgc tccacaataa
     3721 ttagttgtct ttattgctgt tgctagagta tttcctccta ctgtatctat tactccagcc
     3781 catcttggtc taagcagagg tcttcctgag ttatcatcca cttctgacct atgtataaca
     3841 tctttaacac ctaagtttag taatacttct ttttgttctt ctaattttcc tgttgaaact
     3901 acaactgaat aacctaattt aatcaatatt ttagttgcaa ttacagcaac tcctccagta
     3961 ccaccagtga ctaatacatc tcccatattc ttgtctacag aatctataaa tttatacaca
     4021 gataaagctg ctgtaaaccc tgctgtacca taatccattg cttcttttag tgaaagattt
     4081 ttaggaagtt taactaccca actagaagga actcttatgt attctgaaaa accaccagaa
     4141 gtattcattc ccaagtcata acctgttact aaaacttctt ctccaatttt aaaatcatca
     4201 caactactag attctactat accagatgca tcaattcctg gtgtatgagg atactttctc
     4261 gtaacaccct tattaccatt tgcagaaagt gcatccttgt aatttagaga agaatatttt
     4321 acttttatta gaacttcgcc ttctggcaat gtatccactt ctctttcaac tatatttctt
     4381 ctaaaatttc cttcttcttc tgtaatatat agtgatttaa attttttatt cataaatttc
     4441 ctcccaatac atttagtttt atgttaaact aattatagtt tataaatagt tttatgtcaa
     4501 actaatttaa atagattaaa gattggagaa taatttatgg aagataaata tattgtacat
     4561 ttcataagta aaacaaaggc tagtatgatt aaattcattg aaaataaact cagtaaaaat
     4621 ggtttaggtg agttaatacc tactcatgga aatattttaa ctgcacttta tgaaaataat
     4681 ggaatactta caatgaaaga aattgcagct aaaataggaa aagataaatc cactgttaca
     4741 gtgttggtta ataaacttat aaacctagga tatttagaaa gacaaaaatg tacaaatgac
     4801 aaacgtatca cgtatataaa gcttacaaaa aaggcactgc ttatagaaga tacttttaat
     4861 agcatctcaa cacaagttaa agagacggca taccataata ttacagaaaa tgaaaaacaa
     4921 gaatttctta gaattttaaa aaaaattaat gataatttta aaaatgctga ctaaattgag
     4981 cataattata tctcctattg gaataataaa taaaaagaat caaatattgt aaaaatttat
     5041 tgtgatagag aggtagaata tgaatttaaa agatagtaaa actaaagaaa atttattaag
     5101 agcttttgca ggtgagagtc aagctagaaa tagatacaat atttctgcat ctgtagcaaa
     5161 aaaagaagga ttatatataa tagagtcttt atttaattac actgctgacc aagaaaaatc
     5221 acatgcaaaa caattctttt ctaaattaaa agaatttgct ggtgaaaata taagtatatc
     5281 aggagcatac cctgtagatt tatatgacaa gacagcacaa caccttaaag ctgcacaaca
     5341 taatgagctt caagagtggg atgatgtata taaaaacttt ggaaaaacag cacgtgaaga
     5401 aggatttgaa tctatagcta agttatttga aaatatagct gaaatagaaa aagttcatgg
     5461 tgatagattt ggtagatatg ctactgattt agaagaaggt actttattca gaagaaatga
     5521 agatatacaa tggatatgta cacattgtgg ccatatacat ataggtaaag aagctcctaa
     5581 agcttgtcct gtatgtcttc atccacaagg atatttctta gattttaaaa actcattatt
     5641 tgaataaatt aaggcaataa ttctatttaa acaatttact atatttatat caagtatttt
     5701 tataaatact gtattatctt aataacaata aaatgaacca ttgatattac tataagtaga
     5761 aaatgtagtt taaatacaat ttatagtagt tcatcatggt tcattttatt gtttactaat
     5821 ccctataacc tacttaaatc tatctttaac ttttacacac tcacataaaa tctcatcttt
     5881 aaactaaata tttaaataaa gtgtatttta agtagattat tataatacat tatataagat
     5941 aatacactat gataacttta tacttatatc atttatttct tttgtcaagt caacctcaat
     6001 aatcttaact acatcttttt caaactttac ttttttataa tccagacatc ctactacgaa
     6061 tggaactcca aactttctaa acaaataaat ctttccactt tcattgtata ttgatgtaaa
     6121 attttcttct attatattca ctatcaattt taactcttca aaagttatta tagatttaac
     6181 taaaaacttc tctattatgc tcaatataag cagttctttt ttacctatgc tttgttcttt
     6241 tttatataaa ttttgaaata tttctttggt ataattacat ataacttctt tactgagaat
     6301 aaaatcaatg tcaaattctt tattaatatc ctttttcata aacatatttg caatatcctg
     6361 aacctcccat gactaaagtc acagggttcc tgcttcatag aattttgcat actaaaatat
     6421 gtcttactaa ttctccacag gctatccccg tagttcctac ggttcttaca taagttattt
     6481 attttgaatt gttattagtc ttaatccttc ttttaatata tttatacttg catttatatc
     6541 tctatcgtga gtttcattac aactaggaca aatccattct cttatattta agtccttcat
     6601 ttcctcgttt ttatacccac atttattgca tatttgtgaa cttgcaaaga atttacctac
     6661 ctttacaatt tgtctaccat gccaattagc cttgtatttt aattgacgaa caaattctga
     6721 ccatgacaca tcagaaatta agcgagatag tttacgattt ctaatcatat tctttacttg
     6781 taaatcttct atgcaaataa tatcattctc ttttattaat ttagtagata gtttttgtag
     6841 aaaatcattt ctttgattag ctatatgttc ttgaagtctt gcaactttta atcttgcttt
     6901 atttctattt aaactaccga ttgtctttct cgataattct ctttgtaatt tagcaagttt
     6961 gtttaatgac ttcttaagat acttaggatt ttctataaag tctccacaac ttgagataca
     7021 aaattcttta attcctaaat ctaaacctat ctgattatta gtattttcaa atacttcaat
     7081 atctacatta gtacagcata atgatacata atatctacca cttggttctt tagatatagt
     7141 agcattaagt attctacctt gaggtacttg tttatccctt accttaacca taccaagttt
     7201 aggtagtttt atatattgac cacaatacat aatgtttcca tttgtaaagt tagttttata
     7261 tgaaaatcta ttaattttct ttgatttaaa tttaggaaat cctgcttttt ctttaaagaa
     7321 ttttttatat gcattatcta aatcttttaa ggcgttttgt agtgaaaatt tgtcaggttc
     7381 cttaagccat tttaattctt tttttaaatt ggttaaatca gaactacact gtttataagt
     7441 aaaagtttct ttattgtttt tataaacttc tattctttta gcaagatact tattatatac
     7501 aaatctacaa catccaaaag ttttgttaat taactcttgt tgttttttat ttggatacat
     7561 tctaaactta taagcttttt ccactactgc cacctcactt tacttgtttt ttctgattat
     7621 taatatattt tcttatctgt tcttctgtat tttctgatac agtagcaacg aaataactag
     7681 gattccaaag atgtcctccc cataatttct ttttcaactg ttctccatgt tttttcatta
     7741 acagccttgc tgatacacct tttaatgctt ttattatatc tggtatatag tgttgtggtg
     7801 aacaatttat tagtaaatgt atgtgatctt tatcactatt acattctaat atttgaaatt
     7861 tattatcttc agctattttg tttaatatat taattaaatc ttcttcaatt tcatttgtta
     7921 atactggatg tctatatttt acacaccata ctatatggta ttgtactaaa tacacatacc
     7981 ctctaccatg agtcacttcc atttttcatc acccaacata atattaacat agtaattact
     8041 taaaacaagt attcttaagg tttttatatt tatttttaaa taacatacgt aagaaacgca
     8101 aatcttaact tttatcattt ttgaggttgt cgttcacata agttcgctac tacctatgca
     8161 gttctcttat gaacttctta cactttcatg caagcacaga ctatatctta tccttcggca
     8221 ttatccgtta aggtctaccc acttccacta ccgatagctt gtagtgtact tccctcaaga
     8281 ggaatagtcg ttgaagtttt tcctattcgg agcttacctg ctgattgccc attttaaagt
     8341 acttaggatt taaccttata ccatctaacc aattttttct actttcgtaa ctttcacact
     8401 taggtttatt tcatccttat gttttagttt ggttagcttt aggggtttcc agcaattcaa
     8461 gtagtattgg ataggttcta tcctatctct acatataagt ttccctatat gctgactatt
     8521 ttagctacta actcatgact aaagtcacaa gtgtgcatag ctatttttta atcaagagaa
     8581 gtctcttctt tcatagacaa tattaactct attctttcta gtattttatc tcttggaaag
     8641 aaagtctctt gacctgtaaa agctgatttt tttataaacc attcctctgg tattatgttt
     8701 tttcttttcc atctatataa ttgtccataa gatatattag ttttgctcaa taaatctttc
     8761 ttagatatta attcttccat agctcttcta gcccaccttt atactgtttt ttacagtaga
     8821 attatctgaa actgataaat tatcactgta ttcaatattt ccaacatcat aattatctac
     8881 tagagatatg ctttttttct agcatacgaa attttttgca ataatctcca tgcccctttt
     8941 ttatatttat actacttgct ccaacttcat taaaattaga agttccattt aaactaatat
     9001 taacttcttc acaattcaaa aatccattac actccaagat tccacttaaa ttgatatttt
     9061 cacaatctat attctcattt gcttttaaat atccttctcc atgaataata tccgatttta
     9121 tacttccttc tacattaata attccactag tatcaatttc aacagaatta atatttcctg
     9181 tacatctaag aagtcccgat atctcaactt ttgatgccag tatgtttcct tctactttac
     9241 ttaaaccaga tgtaaaaaat tcattacatt ctgttgtccc aaaaactttt gctgaaccag
     9301 aagaatcaaa tttactacat tttacacttc cttctatttt gcctgttcct gatatattaa
     9361 cattatcaaa aattccacct ttacattttc caacaccatc aaatcttagt gaacttaatt
     9421 cttcattcat aatgatatcc tttctttacc gtattttatc tttaaaccta atataacaaa
     9481 acattgttac gttgtcaagt atgataataa tacttaataa agcaactatc atttattttc
     9541 tataaatagg cataaaaata atagggaaat gctttattta aactataaat ctaatttctt
     9601 agattgtggt ttaaataaaa tatatcccta ttactcaatg tttatatatt cattgtataa
     9661 acttctaaaa tataagtctt taaattctac tgtcaatact ttttatacac tgtttgtgct
     9721 atcatctcac acacctaaag gagtaggctt tgcgcactat tctgtaacct acaagacact
     9781 atcttcttct atctattgat aaatttttct attacatcag ctagtctctc catatcagtt
     9841 ggatagactt cacctatgct acctattcta aatgtatcta tatcagtcaa tttacctgga
     9901 tagataacaa atccattatc ttttaaataa gtataaaatt ccataaattc aaactttgca
     9961 tttttaggat ataagaaagt tgttattaca ggtgattgag cattatcatt caccaaagta
    10021 tcaaagccta aagattttaa tcttgaagct attgtaaact gattttcttt atatctagca
    10081 tatctttttt caacagaacc ttcttcttcc aattctaata aagcttgata aaaagctctt
    10141 acaacatgtg taggtgaagt aaatctccat ttaccattat ttttctccat agtctcccat
    10201 tgcgcataca catcaagaga taatgattta gctatacctt tacatttaga taatttctct
    10261 ttattagcta ttataaaacc aaatccaggt actccttgta tacatttgtt agaactacta
    10321 actaaaaaat ctatattaaa atcttcaaca tcaatctcaa ttcccccaaa actactcata
    10381 gcatcaacta tataaatttt gttatattct tttgcaagtt tccctacctc ttgtatagga
    10441 tttaatctac ctgtagtagt ttcacagtga accattgata tatgtgttat atccttgttt
    10501 tcttttaata aattttctac tacatttaaa tccactgctt ctatatcttt aaatgtgcag
    10561 tcaacaaatt gtatgttaag ataattacat atatctttca ttctctttcc atatgctcca
    10621 tttgcaatta caagaagttt accatctttt gaaatagtac ttcctattat agcttctact
    10681 gaaaaagtcc cacttccttg cattaataca cttgtgtatt tatctgtatt ttgggttgct
    10741 agagatacta atcttcttct aacatcttgt actaggttat tatattcaac atcccaagta
    10801 caccaatctt ttaacataga tgctcttact gatttagtag tagatagtgg tcctggtgta
    10861 agtaatatgt aatcattttc tggtacaaaa tctgatttaa tagtttcatt ctctattttt
    10921 attagtatat cttctaactc agccatagtt tctattacaa aatgtgcacc tgcctcttta
    10981 aatttctttg aaactatact catcttagct tttaattctt ccttatccat gttctctact
    11041 tcttcttgtg taagccctaa ctcacttgaa ccttttatta cagcaacact ccacattcct
    11101 gcatttacgc cttcttttac atcacttatt gtatctccta cttttaccat agaactcata
    11161 ggagacaccc ctaaagcttc agcattttta tagcacatcc aaggatacgg tcttccttga
    11221 gatacttctg atggtgttac aagaaaatcg ggtgagtatc ctttctttgc tgcatttggt
    11281 tcaactatgt tcatcatctc tcttgtataa cccgttgtag aacctatttt taatccattt
    11341 tttctcaact tttcaatagt ttcaacaaca tgaggaattg gagtcgtata ctcttctaat
    11401 gtctcaaata acattggctc aaattcagca taaagttcat ttacatcatc ttcagttggc
    11461 actttaccaa acttatctga ccaaatattc tttattctat ccatttcaca catttctctt
    11521 atatggtcta tttttaattt tcccataggt tttcttgctt cttccattgt tacatctata
    11581 cctcttcttt taaatatctc tataaataca ttaagaggtg caaaacatcc ataatctact
    11641 gttgttccag cccaatcgaa tactactgct tttatttttt ctccatatat ctttttcata
    11701 tttatagcct ccatagattc tttttagaat ttttgtgttt ttaattgttt ttacttttaa
    11761 agtataactt tcatatgtta attatacatc atatttaggt taaatatata ttaaatttct
    11821 gtttttagtt gtatttagtt gtttttattt tgtatcatat tcccataaaa tcctaagtta
    11881 caatctaaaa tttactttct aatcttaatc tatgaactga ctatatttta tgaatttagt
    11941 tgtattgagc atagttgtat tatataaaac taagggttta ttttgcttct atccatgtta
    12001 tatttatctc atttaactta tccttccatt cattcggagg ttctacatca caaataacaa
    12061 aatctaattc ctctaaatct gctatcttat acatactagc aattcctatt ttagaactat
    12121 cacataatac aaaactttcc tttgaatttt ttatatattc ttttgacaac aatgccttat
    12181 tttggtctat actactaatt ccaaaactat caagtatacc ttcactagat ataaaagctt
    12241 tatctacgta taagtttttc atagtatcta ttgacattgg acatgctgtc ctttggtgtt
    12301 ttaaatttac ttttccacca ataaatataa cttctccatc aaacaaacct tgattctcat
    12361 aagaaatcaa ttttgataga actggataag agtttgtaat aatttttaaa ttgtttacag
    12421 atattatata atctacaatc tgcaaattgg tagtaccttc atctatgata attgactcat
    12481 tgtcatttac aaacttagct gcatatttag caatactttg ctttttatct aggttagtat
    12541 tgtttctctt tatatgttct ggttcaatca ctccataatt tatttttata gcaccaccat
    12601 ataccttttt taatttattt tcattttcta attcttccaa atatcttctt attgtttctg
    12661 atgatacttc taatcttttt actaattctt tagtgtttac cttccctttt gaatctaata
    12721 atttaagtat ttcttttttt ctatctatcg aatttaaaga cattcatttt cctcctaaat
    12781 ataatatatt tttctcctat aatattacaa tgatacctaa gatttatgaa atcatattta
    12841 tgtattaaat tttttactta attaaagtta ttttcaaaag actttgtatt atcattaaaa
    12901 aagtccatca aatattagta tcagatggac tttgtaaaat tttattttat aaattaatat
    12961 ttaaagtcta actactaatt tattttcttg tctccaagaa ttttactaaa ttatttacag
    13021 tagacatatc ttttctctct aaatcagttg gttgaagctc tatccctaat ctattttcaa
    13081 tttcaagtaa aacttcaatt atagctaatg agtctaaaag ttccgtctca aataaattaa
    13141 ggtctaaatc ttctcttatc tcatcagtcc ctaatacatc ttcaaatatt tctataactg
    13201 tttcttgcat aaattttcct ccttaaaatt aagctaaata acctgagaat atcagcaatc
    13261 caaaacacac aatatggaat gtaatgaaaa tctgcactct ctcgaaccat ttatcttttt
    13321 tatgtttttt ataaaattta gattttcgct gatatatatc agttaacaca agtgccaatc
    13381 cttggtatac accataagca acataatacc aagttagacc atgccaaaat cccattgtta
    13441 tcatggttat catctgagcc acatgagcag cagtagtcct tttcttaaat cttttctttc
    13501 tcattgatga cataacaaat ctagaaaaaa tataatctcc aaaccatctt gaaagactta
    13561 tatgccatct tgtccagaac tctttcatat ctttactgat aaatggcttg tcaaagttta
    13621 taggtacttg tattccaaat atgtatcctg tacctatagc aaataaacta tatcctgcaa
    13681 aatcaaagaa caggtataaa ctatatgcgt acatataact taaaatattt ataaaactca
    13741 tatctttagg tattcttgat acccaatatg tatttatcaa aaatgctata acaaacttat
    13801 aacctactcc catgacaata ttttttattc ctggcagtaa gtattcttct atatactctt
    13861 ttctagagat ttgtttttcc aagtcctgtt caaatcttct tgacctatca ataggtccag
    13921 aacttaaagt tggaaaaaat aacataaaat aaagcatctt tgaaatttta acttctttta
    13981 tagctccatc ataaatttca ataaccattt gtatagttct gaaatttaag tatgatattc
    14041 caataaatcc aattattcca aaagaagtaa ctggagatat tttatttatt attattggga
    14101 gcattgatgc aaacaagaat ccccaatata tgtatttatt tttagttttt cttcttacat
    14161 attcatatcc tttaactatt attacttcaa gaataataaa tattaccaag tactttagtt
    14221 ggacatcaat tcctactatt aagaatatca taaacaaact tgccaacata ccataatact
    14281 ttatattctt gcccattaga cctaaaatta ctgctggtat tgatgttaat aataatatat
    14341 aaagataaaa ataatctcca tattgtgaaa aaatcattaa atttcctcca taagtttctt
    14401 tctgtctatt ttaccattga tatttgttgg aaactcagag attattgaaa tatttcttgg
    14461 aatcatatat gaaggtatat actttccaag ttcctttttt attatcatcc catttttaat
    14521 attacttaaa tcattctttt catttaactc aacaatacct tttaagtaag caattttttc
    14581 gtccttatat actggtaaaa ctactgcatt ttttacatta tgtacttttc tcaaattatt
    14641 ttctatatct tctatttcaa ttctaaatcc atttaattta atctgaaaat cttttcttcc
    14701 acaataatat atatttccat ctaaaagata tcccatatct ccagttttat aagctctcca
    14761 ctttacacca tctatttcat catagaaaaa tacttcatca gtcttttctt tattattgaa
    14821 gtaaccttta gaaactgatg gtccaattat tataatttca cccttttcat tttctttaag
    14881 ctcatttcca tcttcatcaa gtatttttat tttacaattt gacatagggt atccaactgg
    14941 aagacttttt tcatcatcta tagccttttg agtcatatca tttacactta caccaacagt
    15001 agcctcggtt ggtccatatc cattgataat tcttgtgttt ggaaatctac tcataagttc
    15061 tttagtaaga ttttttgaaa gtgcttctcc tatgaatatc attgactcaa ggttaggaag
    15121 cattttacta ttaaactctt tttcagttat acatactcct gcaaaagaag gagttgacac
    15181 ccatacagct atatctgaga tactaaattg tctaaatagt tctttatagt ctgctaatac
    15241 atcttttgat attgaaaata atgtagctcc atggataaga ccagggtata ttgttgtaac
    15301 tgaaaggtca aaagaatatg ctggttggtt cattattact ttttcacttc catctatgtt
    15361 tagatatggg cttatccaat ctgaaaagct atctaaattg tttgaactta tttgaacccc
    15421 ttttggcttt cctgtacttc ctgaagtaaa tagtatatat gcattttcat catcttttac
    15481 ccagttttct ttatctaatg attttccctg atattcattt attatataat ttaatttatc
    15541 catatcaatt acattgatat ctccaaaatc tttttcatca ctaaagttaa ataatacctt
    15601 tggttttatc tctttagtga cttcaaaaac tctatcaatt ggaaaactaa tatcaagagg
    15661 cacatacgct ctacctgatt ttaaagctcc tatcatacat gccattatca tgttttcttt
    15721 atttccataa attactatag gagtatcttc ttctttgtat acatccttta gaaatactga
    15781 tatagcatct gaatattcat ttaaatcttt ataagaaagt ttatctccat tacacattag
    15841 tgctgttcta tctgtatttg aatatttttt tattccttca ataattttca tataagaatg
    15901 ctcctttaaa atccgttata aataaatggc aattctttaa atggagtaaa tgttagaact
    15961 cctatcgcca atattataac catagttaaa caaatactag ttaacaaatc tttattgttc
    16021 tttaaatatt ttaaataatc tctcacagac atctacccat cctttcgtac caagatgcat
    16081 tacatccctt aaataatact tatctgaccc tttatcttta aggtttagaa cttcaaagcc
    16141 tttgctttct gctatttttt gtgctttatc gtagtactga tttctttctt tttcagaaat
    16201 accagtcaaa ttatagaatt tatccatact tgggattaat acaacaactg gcttaatacc
    16261 taagtcagta catacattta gcatcagttt ataattttca aactccttag atgttaataa
    16321 atttacatct ttgtctcttc ctttgtattg ctctatacca tctttaaaat gctctttata
    16381 atagtactta tcaatattta gtggattttt accaactctt tttttagcat cttcaatggc
    16441 tttctttctc tcatatgacc aatttattgg tctttttctt tttgttgctc tctttttatc
    16501 tagcttaatt aatcgtttat aaagaatacc cttttcttta agagctatac aatactttct
    16561 tccttgaaaa taaggctcta aaagcacctt ttcagctttt tcaggaaatg tcttaggctc
    16621 atatagctta gcatataatg cttctgcttt atactcgtca cttccccata ataacttact
    16681 tgattttttt gcatattcaa tcttattttg tttagatatt tttggattat ctaaaaatcg
    16741 ataaaattgt attggtgaaa atctagactg ataatggtga cttgtgactc cgtctttttc
    16801 cataaaccat tgcatagaaa ttaacaagac aactttctta ttatcaatat taggattcat
    16861 acttcctaat attgcagcat cttgtaatgt ctgagtatag gctctcccaa ttgcaaacac
    16921 cttattttta ctcctatttg tattaaaata gtactttgga tgttgttttg ttgaattact
    16981 aagttctgat gaccccaaaa tcataatatc cttttctctt aaaaaatgat tatttgctgt
    17041 aaccccttta tcttttatat cacttaaagt atcatccata attggaagta gatttttctc
    17101 cctcaaaagt tcatcagttt tagaatcaag aaatttgtct aacccaaata aaaatactac
    17161 gcctattata aaaggtgtaa taaagtatat caattttctc atattttctc tcctctaaaa
    17221 atattcaaat ttatgttatt attaatcata ttagttttga tatgtatatt caactacaaa
    17281 attgtaataa aatcgtcaaa actttttttg atactgttac aaaattgtaa aaaaaaagaa
    17341 aaaaacgcca aaaataaatt tctttttagc actttttcat acttataatt tgacatttta
    17401 acacttggtt aagtatacac cttaccttaa cttaaaatta aatttattta agaatatata
    17461 ttataaattc ttatattttc taatataaac tatatactat cagctggata aacaatacta
    17521 ctttgtcttc ttatctcatc cataatttcc attactatta ttgaattttc atgagaattt
    17581 atatttgatt ctattttatt gttatttata agacttataa actctacaag ttcataatac
    17641 attccttcta tttctctagg cttttcctct gctttttctt ttggaataga tatatcttct
    17701 tctcttccat ctctgtattt aataatagct ttttcaaata gattaagctt ttcaattatt
    17761 atacttccct cttctccttg tatttcagat ggtatataag aatcagctac tttagaatac
    17821 tgaattatcg catccatatc atcatattga aatacagctg aaccttctcc atccactcca
    17881 gtttgaagta tatgagaaac tgcctttaca gtttttggag caccaaataa attcaccata
    17941 ggatgtatac aatacactcc tatatccatt aaagctccat ttgacaactc ttttttaaag
    18001 gcattttcta taattccatt tttatattta tcatatcttg aagaatactg acaatagctt
    18061 ccaaaaaatc ttcttatttt ccctatttta tataagtttt ctttaactgc tttaaagttt
    18121 ggaacacatg taattctcat agcttccata agcaatacat tattatcttt ggctgttttt
    18181 atcattgatt tgacttcttt taaattagat gctaacgact tttcacaaag cacatgtttt
    18241 ttgtgtttta aacaagtaat ggtttgcttt gaatgtaatg catttggaga agctatgtat
    18301 acagcatcta tatccttcga tttagccatt tgttctaaat catcaaaaaa aatacttgct
    18361 ccatatagag ttccaaattc tctagctttt tctaaatttc tagaatatac agcaaccaat
    18421 tcaaagtctt taaccctaga tgcagctctt agaaatatat ttgctatatt gcttgtccca
    18481 acaataccaa atcttatttt acccatcata aatcactccc cattttctac actttatttt
    18541 aattttaata aaaaacttta caacttatag atatattata aaataatttt atcaaataaa
    18601 aaagaaagct aattttaaat gatttcacca ttttaacata gctttctttt aactacaatc
    18661 taaattcaac ttatattttt aaagttatct ttctactata tctttatttc ccctcaaaaa
    18721 ttttatagta agaatttcat ccacaaacaa tgttactaaa agtatagtta caacaattgg
    18781 ccaataaggt attataagac tatataaact atcaactata tacacttgaa aatatctaac
    18841 tccaataaat gtcaatatag tccaatatac agaaaacttt agacatacta ttcctctact
    18901 attgtactta taatctgaat aatcccaata gaccttatta aaatatactt tcataagtat
    18961 tcctgtaata tattctacta ctgtcggcac tactagacat aataaaagca atgcaaatat
    19021 attattgggg tcaataaatc ttgagacctc tattataatc gacattgcaa ttgcatacat
    19081 tggtttaaat ggaccattta aaaatccatc ttcttgaaaa tgcccttgtt tataataact
    19141 atataagttt tcaattatcc aacctataaa accatacaag aaaaaattaa ataaaaaata
    19201 taatagagaa cctacattat ccatgaatat tcctcctagc tgtttatact tattttttct
    19261 catattcatg gatttattct aaatcaaaga aattatattt aatttattta attaatactt
    19321 tatattatag attgtgacat tctttagagt tcaaactttt taggtattct ctaacttcca
    19381 gtaaattttc aagtatctta tgtgattgtg atttaatttg ctcatctggc tcttttaaat
    19441 ctggtacatt tatacatctt ataccaccat tgtatgcagc ttcaactccc ataggcgaat
    19501 cctctatgac aatacaattt tggggattaa catttatctt tttagctgct tttaagaata
    19561 tctcagggtt tggtttagag tttacaacat catctccaca aactatagca tcaaagtaat
    19621 cttttaaatt tgccttagct aatctcttta ctgctctttc tctctttgtt gatgttgcaa
    19681 cagccatttt gtatccattt tcctttaaaa aagagattag ttcattgact cctaatttga
    19741 taggagctcc cttcctctcc ataaattcaa tcatattttt agttttttcg tcatataaat
    19801 ctattattgg tacagaacta tcgtatatat ctgtaagacc ttctattatt cctttacgat
    19861 ttcttcccat aactgatgta taaatttcct tagtcatagt atatccatac ttttcaaacg
    19921 tctccatcca aaattcaaga gaaattctct ctgagtcaaa caaaactcca tccatgtcaa
    19981 aaataattcc ttctactttt tgcatacaat tcctccaata ttttttgata taattatatt
    20041 acacttttta tgattaattt tacaaccctc aatttatcca attctaatat tgtaaaattg
    20101 taattttcaa aagttacact ttggtttact ttaatatttg aaccaagcat ataggatatc
    20161 cacccaccta tactgtcaaa tccatcatgc tctatatcaa gtccaaaata cttattaata
    20221 tagttgatag attcagttcc atcaactaag taagaacctg ctcctatttt cttaatatga
    20281 gtctcttctt tgtcaaattc atcttgaatt tctccaacta tctcttctag tatatcttct
    20341 attgttacca caccagatgt accaccatat tcatccacaa ctatagcaag ttgaagtttt
    20401 tcctttctta ttctctcaag agctttatct atagttaaat tttcagatat atatataata
    20461 tctctcaata tttcttctag ttcaatttta ttttcattta tcttttgatt gtataaatct
    20521 cttatatgta caaaacctaa tatatcatct ttattttttc tgcatactgg atatcttgta
    20581 acaccttcct cttttaaaat agctaatatc ttttcttcag aatcactttc atatatacat
    20641 accatatcag ttctaggaac cattatctct ctaattttct tttcttcaaa ttcaaaaata
    20701 ttatcaacta atctttgctc tgattcatct ataagtccac ttttataact ttcttctact
    20761 aatagtctta tttcgtcacc tgtatggggt tcatcaacct catcagcttg tgaatatcca
    20821 aatggtttaa gaaataaatc agtacttaag ttgaaaaaat atattattgg atatgttaac
    20881 ttataaaatc ctactaataa aaaagatgta ctcaacatta ttttttctgt attataaagt
    20941 gctaaagctt taggaaccaa ctctcctatt acaacctcca tcattgttat aattaaaaaa
    21001 gaaatggaaa ttgatatagt atatataata ctttcactaa gattaaatac acttactatt
    21061 ggtaaaatta actctttaac tgtagattct cccatccaac ctaatgcaag tgaacaaagt
    21121 gttataccaa gttgacatgc agaaagatag gaatttaagt tgtcttttat tattttacat
    21181 ctttttgcat tattattacc ttcagttatc atggtatcaa tcctagaact acgaagtttt
    21241 accatagcaa attcacaagc tacaaaaaaa gcatttatca aaacaagcat tactataagt
    21301 gttactttta ataactcccg cataaagtat tggttcttat aatgtaagaa atctataaga
    21361 actcaaagtt ccccccttat attaataaat ttaatttata atatatattc tatcatattt
    21421 attaatatat cctactttat tacaaataat ttttataaac taaataaccc cttttaatat
    21481 ttatgactgg ctatttgata aatattaaag gggttattta gttatcattt tttatttcta
    21541 aaaatctttt ctcaaatgat ttagttatct atttatccaa ttttttacat aatttaatga
    21601 ttaaaaatat t
//
LOCUS       DAEHWO010000072        21480 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEHWO010000072 DAEHWO010000000
VERSION     DAEHWO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21480
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.072"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(56..742)
                     /locus_tag="KNP54_002998"
     CDS             complement(56..742)
                     /locus_tag="KNP54_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBF0893864.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(791..1324)
                     /locus_tag="KNP54_002999"
     CDS             complement(791..1324)
                     /locus_tag="KNP54_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBF0893865.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(1368..2000)
                     /locus_tag="KNP54_003000"
     CDS             complement(1368..2000)
                     /locus_tag="KNP54_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBF0893866.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(2090..3169)
                     /locus_tag="KNP54_003001"
     CDS             complement(2090..3169)
                     /locus_tag="KNP54_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBF0893867.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSDVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(3302..4648)
                     /gene="pepV"
                     /locus_tag="KNP54_003002"
     CDS             complement(3302..4648)
                     /gene="pepV"
                     /locus_tag="KNP54_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBF0893868.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELNKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(4717..5997)
                     /locus_tag="KNP54_003003"
     CDS             complement(4717..5997)
                     /locus_tag="KNP54_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBF0893869.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(6124..6384)
                     /gene="hfq"
                     /locus_tag="KNP54_003004"
     CDS             complement(6124..6384)
                     /gene="hfq"
                     /locus_tag="KNP54_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBF0893870.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(6498..7433)
                     /gene="miaA"
                     /locus_tag="KNP54_003005"
     CDS             complement(6498..7433)
                     /gene="miaA"
                     /locus_tag="KNP54_003005"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBF0893871.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINKKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(7471..9438)
                     /gene="mutL"
                     /locus_tag="KNP54_003006"
     CDS             complement(7471..9438)
                     /gene="mutL"
                     /locus_tag="KNP54_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBF0893872.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(9449..12292)
                     /gene="mutS"
                     /locus_tag="KNP54_003007"
     CDS             complement(9449..12292)
                     /gene="mutS"
                     /locus_tag="KNP54_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBF0893873.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIENLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALIKQNDDKEKINQVDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(12452..13186)
                     /locus_tag="KNP54_003008"
     CDS             complement(12452..13186)
                     /locus_tag="KNP54_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893874.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(13155..14168)
                     /locus_tag="KNP54_003009"
     CDS             complement(13155..14168)
                     /locus_tag="KNP54_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0893875.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(14190..14960)
                     /locus_tag="KNP54_003010"
     CDS             complement(14190..14960)
                     /locus_tag="KNP54_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893876.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(14935..15225)
                     /locus_tag="KNP54_003011"
     CDS             complement(14935..15225)
                     /locus_tag="KNP54_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBF0893877.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(15356..15455)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      16075..16164
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16217..16393
                     /locus_tag="KNP54_003012"
     CDS             16217..16393
                     /locus_tag="KNP54_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893878.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(16508..16864)
                     /locus_tag="KNP54_003013"
     CDS             complement(16508..16864)
                     /locus_tag="KNP54_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0893879.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            17331..18079
                     /locus_tag="KNP54_003014"
                     /pseudo
     CDS             17331..18079
                     /locus_tag="KNP54_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816229.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
     gene            18310..18921
                     /locus_tag="KNP54_003015"
     CDS             18310..18921
                     /locus_tag="KNP54_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBF0893880.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            19219..19557
                     /locus_tag="KNP54_003016"
     CDS             19219..19557
                     /locus_tag="KNP54_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBF0893881.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(19964..21400)
                     /gene="miaB"
                     /locus_tag="KNP54_003017"
     CDS             complement(19964..21400)
                     /gene="miaB"
                     /locus_tag="KNP54_003017"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBF0893882.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         6980 a         3544 c         2321 g         8635 t
ORIGIN      
        1 aaaaaattta gacaaatctt aggttattac tctttaaatt atttttaaat tatttttaaa
       61 ttattccaaa tacgccaaat aatattggta taaatatagc tggtaacaaa ttggctactt
      121 ttatattcgt taatttaagt acatttagac caagtcctat aattaataaa cttccagctg
      181 ctgtcatttc tgtgactaca ggatcactta aaaatccatt taaaaatgat gctcccacac
      241 atataatacc ttcatacaaa aatacagata ttgcagaaaa cattacacct atacctaaag
      301 aagcagtaaa tataattgaa gctattccat ctataacaga ttttacaaat aaagtatcat
      361 gacttcctgt aagaccactt tctaatgaac caactactgc catggctcct atacagaata
      421 ataaactaga tgatataaaa ccctctgcta tagaatcttt tttatttcct ttagaaaatt
      481 tactttgtaa aaaagcaccc aacttattta cccatttgtc aatatctatt aattctccta
      541 tcagagcacc tacagctacg gatattattg tcactaatgt gttttttcct tctagtgctc
      601 ctgatatacc aatgtacaat acacataagg caattccatt cattatagta tcgcttactc
      661 tttgaggtaa tcctcctttt attataagac ctactataca tccacctgca attgctagac
      721 tatttgctat tactccaaac attttttctc ccctcgatta gctaattgaa atttatccta
      781 ttattaaaac ctaaacatct atactttgta ttggatattt taaatattcc aaaaattctt
      841 caaaaccttt tctagatata tttacagttt tagtatttat gttaggatga aaatttaagt
      901 aatcttcttt aattacatct ttatctatgt aaagctcaac ttttctttct gtatcattta
      961 ttaatgaaaa aggatttaca cttccaggaa gaagtttaag tacattgtat agtctttcag
     1021 gtgaagcaaa cgataatcta gaacttccta tcttatcttt aagtgagttt aaatcaactt
     1081 gtttttctcc tttaactaca ataagataat acttatttcc tttggcattt cttaaaaata
     1141 aatttttaca ttgacacccc tttgttattc catctaaaat gactaattgc tctgctgtat
     1201 atacagcttc atgctctact acatcatatt caacatttaa tttatccaaa atatcatata
     1261 ttttagtttc attcatgcta gattcatttt catcttgttc ttttttatta tttaaatcac
     1321 tcatactttt ctccttaaac acttcatcat aatatcattg tgaggtatta ttctactata
     1381 gctattgctc ttactggagc tccatcagca tcattatact taaatggtgc tgctataaat
     1441 agaaattttt ctggaacatt ttctaaattt gtaagatttt ctatgattat ttttcctttt
     1501 tcaaataaaa tatgatgcac ttcaaatact gatgtgtcat atctatccac tgatagcata
     1561 tctattccta tgccttttat attagtatta gctatatagt ttgcagcttc ttttgttaat
     1621 gtaggataac ctacatagta ctgcttttta tcccaaaatt ttgaccaacc tgatttaaat
     1681 attataaaat cactattttt tatttcatct tcatattttt ttagatattc taattctata
     1741 ttctcatttc ccttttcaag ttccaataca taagctttcc caacaaaatt ttctatatcc
     1801 aacttatcta gggtctcacc tttagtatac atatgtcttg gtgaatccat atgagttcca
     1861 ttgtgagaaa atacactaat taatgtttct tgataaccat tttcttcaat aatagctact
     1921 ttcttgatat ctggtctatt aggctctgca tatacaggca tgtcattatg tgtcacatga
     1981 gttaaatcaa aaaccttcat ctttatatac cccctatgtt tttattttct attatatacc
     2041 taaattcatt ttatttctat cagattttat tccattatat accatactac tatatatttt
     2101 ttataaacct caagggattt accgaaaaat cttggaaaga attatcagta aatataacat
     2161 cttcacccaa aaaacgttta taccttcctt cttctttctt taaagtaatt ctctgttttt
     2221 gtgaatgatt attaaaaacc attatcttaa gaggaggttt ttttctatta gtctgcactc
     2281 tttttaacat gtattttatg tgcatatcag cttcaggaaa tgaatatcca caaaatatta
     2341 aaaggtcagt atctcttaaa gttttttctg tttcattcca aacatcactt aaaaatatgt
     2401 ttgacatatt cttaaaatat gttggtggca ctataatagg ttctgttaac tcaccacact
     2461 ctaaacattt tgtctctgaa ctattttcaa taagcttcat gacaccacct tcatgtggtg
     2521 taagagttac actattacaa atggggcaat aaagccaatt caatgaccca tgtatcttat
     2581 ataatttgat taatggttct tttggttttc tccaatttaa ctcctcttta aaatttgtaa
     2641 actccacacc ataatcaagc ataattggca aatcattctt atctcttaat ccagtaactg
     2701 tattgtctat atgtatatca taatttgcac taataaaagt agtatcaaga agcaaatcat
     2761 tttccaaaag attttcaact aaaagtttat gatatttatt atctgttcta ggtgtattat
     2821 gaattgcttc agccattagc agtattaaat attgtcttaa aaaacgtata ctatcacttc
     2881 tgttatttag attttctagt ccaaaatttc taaatgcttc ttttctttgt tctgctaagt
     2941 ctaaaagacc taaaacttct tcaaaggtag gaaaatttgc attatctata ttatctttta
     3001 ctatatcaat attgaacatc tgtttaaaga aaatatacaa ttctctattc attttggtat
     3061 tataatttgt gggatttagt tttttaaaat attcgctaaa aagttcattt tgaataggta
     3121 gattctctgc tgctgaagct cctgctccta aaaatattgc tattttcata tagttcctcc
     3181 taatataaat attactccta tttttatatc cattaaatat ccatatcatt tattttatga
     3241 tacaacaata aagctgtctt ttactagaaa aaatcctatt acaagacagc cttatattat
     3301 attaaatctt taataattcg taaatagaaa gagcatatat ttgagtagct tttataatat
     3361 cctctactat taagtattca ttagcttggt gttctgtttc tggttttcct ggaaaaatag
     3421 ctccaaatgc aacacaatta tctaaagctc ttgcgtatgt tgctcctcca gatgaaagtg
     3481 gtgttccatc aagaccagtt tcttcttcat atacttttct aagtgtctta acaagaagag
     3541 tatcttctgg aacatagatt gaatccaaga aatcatattc ttcataattt aaattgtatt
     3601 tatctgtcat tttctttaac tcttttacaa aatcatcctt tttgtatgtt actggaatcc
     3661 ttacatctat tcctgcaaat tctttttcgt tatcaatagt tactctacct atatttactg
     3721 ttagtttacc tgatacatca tccttgcagt taggaattat attgtttcca ttagcatctt
     3781 caccaataac ttctgctaaa aacttaatta tattagaatc tatacctata ttattaagag
     3841 ctatacaaag tctagccact gcatttatac cagtatcact tgctgctgaa tggacactct
     3901 ttccaattat acagatttta ttaccttcaa cagtatactc aaaatttaat ttattaagtt
     3961 ctttttttaa tttatcagag tattttccaa tatagattgc tttacctgga actgcattta
     4021 aagcctttcc aactgacaac tctatatcac ttttgctatc acaagtcaaa tgaacttgta
     4081 aaagaccttt ctctgcattt gttattggga atctagaatc tggagtaaat ccatagtttg
     4141 gtatttcttc attattttct ttatatttat ttatacatct ccaaagattt tcttcatcag
     4201 ccccaaaaat gaatcttatc ctcttattaa agtctacatt taaatccata agagctttca
     4261 ctgcataaat tgctgatatt gtaggtcctt tatcatcttg tgttcctctt ccatacaatt
     4321 taccatcttc taaaacagct tcaaatggag ggtaattcca gctttctaaa tcaccttctg
     4381 gaaccacatc aacgtgacca agtataccta tcattttttc accttgtcct atttctgcat
     4441 atccataata tccatctttg tatactgtct taaatcctaa agatttacat aaatctaata
     4501 tacctcttaa agctttatct acattttcac caaatgggca attttcagtt gcttcagata
     4561 taacactagg tatttttaca ctttcttgta ttgaagaaat catttcatct tgtagagaat
     4621 ttactttttc tttaatttgc tctttcatat tatcaccctt caattttcat cataatatac
     4681 taataaatat tttgaccttt taaaaaaaaa atatgcttat tttttcagtt tttttataaa
     4741 ttcaatcgct tttaaagtcc ccatttttga atggtcaaat gtaagtccac cttggaaata
     4801 aacattataa ggaggtctta ttggagcatc tgcacttaat tctatagaag aaccttgtat
     4861 aaatgctcct gctgccatta tgacttcact ttcgtatcca ggcatgtccc aaggaacagg
     4921 ttttacataa gaatcgactg gtgcagcttc ttgtatacct tcacaaaaac ttattacttc
     4981 atcagcatta ttaagtctaa tacattgaat aatatcactt cttaagtcat catattttgg
     5041 taatacatca tatcctaatt tttcaaaagc tcttgagcaa aagatagctc ccattacagc
     5101 ctgagatact atataaggcg ccaagaaaaa accctgaagt acatttctag ttgttccaaa
     5161 agtaagacca cattcttttc ctattccagg agaagtcatt ctataagata taagctcaat
     5221 caaatctttt ctaccagcta tatatccacc tgtcaatgca agcccaccac caggattttt
     5281 tattaaagag ccagccataa catctgctcc aacatcagta ggctctttgg tatctaaaaa
     5341 ctcaccataa caattatcaa ccattactat agcttctggt ttaacagact ttattacttc
     5401 tatagcttct tttatatcac taattgaaag tgattttctc caagaatatc cttttgacct
     5461 ttgtatcata acgagtttag ttctatcatt tattttgttt ttaattcctt ctaaatctaa
     5521 gtttccatcc tctaaaaaat ctacatcatc atatgtaaca ccatactctt tcaatgaacc
     5581 tttttcttct cttatgccta taactccctc taaagtatca tatggtctac cagtaacaga
     5641 taaaatttca tctcctggtc taactatacc ttgtatacat aaagtaagtg catgtgtacc
     5701 atttacaatt attggtctta caagagcatc ttctgtatta aatactttag aataaatttc
     5761 ctctattttt tcacgaccaa tatcattata tccatatcct gtagtccagt taaagtgcat
     5821 atcacttagt ttagattctt gcatagcttt taaaacttta tattgattat attctcttat
     5881 ttcttttatt tcttcaaact tatcttttat ttcttccatt atttcttgcg atagtttaaa
     5941 agtatcatca tctattccat agtagtcttt taataattct tttgtctcat taagcatttt
     6001 atcacctgtc tctttattat tttatttaaa catgtaaagg agactatttt actaaaacaa
     6061 ataaattata gtttataagt tagtataagt ctcctctcaa tcatcttaaa ttaaattaat
     6121 tatctatctg ttgttattat tattgttgtt ttggttttga tttgttagat taatatactt
     6181 tccaggttgt atagttgata cagcatgttt ataaatcatg ttttgttgtc tattatcccc
     6241 ttctattaat attatataac tatcaaaccc ctttacaagc cctttaactt gcactccatt
     6301 aactaaatat atagtaacag gtatcctttc tttccttgca ttatttaaaa acaaatcttg
     6361 taaatttaaa actgtatttt tcattagatt tgtaccctcc caagattaaa ttgaacttct
     6421 aaaatattcc taccttatat tctatataag ttatgacaaa ttttcaatat taagttgtat
     6481 acttaaaaat ttatatatta ttttatagaa tctttaatat ataagattat ttcatttttt
     6541 aattcgtcta tattttcata ttggtctaaa tcaaaccatt ttgctgtttt atatctttta
     6601 aaccatgtta tctgacgttt tgcatacctt ctagaatctc ttttaattat ttcaatagct
     6661 tcttcgtatg tatattctcc atccagatac tttaatatct ctttataacc tataccttgc
     6721 attgatatca tatctttttt aaatcccata cttaaaagtt tttttacctc ttcaaccaat
     6781 ccatttttaa gcataatatc aactctcata tttattcttt gatacaaatg ttctctatct
     6841 ctatttagaa ctattattat tggttgatat tcttcattaa attttaaatc acttgaaaaa
     6901 tcattcattt tcttaccact tagacaaact tcaagagctc ttatgaccct tttagtattg
     6961 tttttatgga ttctattagc agattcttca tcaagttctt ttaacttatt atgcatgtaa
     7021 tctattccct tttcagcaag ttgtttttga agttcttctc ttaattcatt attggcatca
     7081 gattgtgcaa aatccatatt atatattaaa gagtttaaat aaagtcctgt gcctccagtt
     7141 actaaaacac atttttcctt tttatttatt tcatgtatat atttttttgc tctttgttga
     7201 aactctgaaa ctgaaaatgg atagtcaggc ttaacttcat ctataaggta atgcttcact
     7261 ccttgcatct cttcctctgt aacttttgca cttccaatat ccatatattc atatatttgc
     7321 atagaatcag ctgaaattat ctctgcattc atatcttttg ctaattttat tgacaaatct
     7381 gtttttccaa cagcagttgg acctgtaagt attataagtg gtattttttt cataacattc
     7441 ctttccatat attttaaata tccaaatatt ttacataatt cttttaaaca ttttttctat
     7501 ttctgtctta gatatttcga ccattatagg tcttccatga ggacatgtaa atggattctc
     7561 acacttttct agctgttcca ataaactttt tatttcaata tcgtatattt tatcatttgc
     7621 ttttatagca gacctacatg ccatagatgc aaatctctct ccttttaaat cataattact
     7681 tgtaatttct tctatattat caattatttg aagtataaat ttctcggttt caggtactcc
     7741 aaatatagta ggaacacatc ttaccattat atgattattg ccaaaaattt ctagctcaaa
     7801 accaaatttc ataaataact ccaagttatt ttcaatttga agcatatcta catttgatac
     7861 ttcaataacc actgggtcta aaagtatttg catatttata tcttgtctat agaacttctc
     7921 catatatctt tcatatagta ttctttcatg tgcagcatgt tggtccaaca aatacataga
     7981 atcgtctttg ctcaaaatta tataagtatt aaatacaact ccaattacag aatatccgta
     8041 taaagaaaac ttgcgttttg aactacacaa gtattcttct tcactgtcct taatactatc
     8101 tcctaagtaa taatttcctt catttttaat tccatcaact tgaaactctt cttgtatatt
     8161 atcatttgca ctatcttcac ttagataatt aatgtttttt acatcatctt ctacacttgc
     8221 atttaggact tcacttactg attgaaattc atttattggt ttttcacttg ataaagtaac
     8281 aacttcaatg acttcatcct tacctttagt aatattacta tttttaggag tagattctaa
     8341 taaatcatta tttcttaatt tataatctgt acttttttct ctactgttaa tagcgattct
     8401 aggttgtgtt tttttatcac tataagtagc atattttcca ataagatttg agtgtattaa
     8461 tttaaccttt aaaaaatctc taagttctat atacacttct tgttcttttt caaatttaat
     8521 ttcaagttta ttggggtgta tatttacatc tatacatgat gggtctactt ctatatttaa
     8581 gaagcacact gcatgtttac ctattggaat tatagactta taactttctg ttattgcatc
     8641 tatgattatt ttacttttta caaatctttt atttatatag atatgttgta agtttttatt
     8701 tgaacggtat atattgttat tacctatata tccattcatt ttaaagtgat tgcacttaaa
     8761 ctctacatct attatatttt ccgttatttc ttttccatat atacttctaa tagtgtttac
     8821 aagctttcca tcccctggag tatttagcat ctgtttattg ttatttgtat atttaaattg
     8881 aatgtttgga ttacctattg caagtttatt tatcaaatca cttatattta tagtttctgc
     8941 atgagtagat tttaaaaatt tctgtcttgc tggtgtatta aagaaaatat cttttataat
     9001 gatggtagtt ccattagtag aacctattgg ttctttcgat attatttttc caccttcaac
     9061 atatatttta gttcctatta tttcatcttt agttttagtt gtcatttcta attttgatac
     9121 agctgaaata gatgccaatg cttctcctct aaaaccaaga gagtataaat catacaaatc
     9181 atcaattttt ttaattttac tagtagcatg tctcaaaaat gatttttcaa cttcacttga
     9241 aggtattcct attccattat ctgtaatctt aattagactt tttcctccat caattatatc
     9301 tatggaaatt ttatttgcac ctgcatcaat ggagttttca ataagttctt ttactacaga
     9361 agaaggtctt tctacaactt cacctgctgc tatcttattt atagtcaaat catctaggat
     9421 gttaattata tttttcattt ttacacctct aagattttat ttcttttgct tttctttgaa
     9481 gattataaag agagtttata gcatctaatg gagtcatatt taaaatatcc agatttaaaa
     9541 tttcttctga tagtatatct ctatttacac tatcaaaaga gatttgagtt aaggctactt
     9601 cttttacaga atccacttga ttaattttct ctttatcatc attttgcttt attaaagcaa
     9661 cttcatcatt taatgcttta aatttagaat ttaatttatc ataatccttt tttatatgtt
     9721 tgtagtcttt tactataagt tcatgttcta tttttagaga ttcatattta ttcttaaaat
     9781 tactttgatt taccttaact aattcttcgt ccaaattact attaattata ttattgtttt
     9841 ctttatctcc atttattgca acactgttgt aaacatgatt tttttccaag tctttaagta
     9901 tatattttgc tctttctatg acttcgtctg gtaatttagc taatttagca acatatattc
     9961 cataactctt gtctgctccc tgaggaatta tttttcttaa aaatattatt ccttccccat
    10021 cttctttgac tgctattgaa taatttttaa cctctttaaa ctcttcttct aaatcagtaa
    10081 gttcatgata atgtgttgca aataatgtct tacatctaat atttttttga atatattcca
    10141 ctattgacca tgctaaactt ataccatcat aggtactagt tccacgacct atttcatcta
    10201 atataactaa acttctctct gttgcatttt ttaatataag ggatacttcg ttcatctcta
    10261 ccataaaagt agattgacct tgagataaat cgtcactagc tccaactctt gtaaatattc
    10321 tatctaatat tggaatatca gcagactctg ctggtacaaa tgagcctata tgtgccataa
    10381 gagctattat agcagtttgt ctcatatatg ttgatttacc tgacatatta ggaccagtta
    10441 ttatgttaat aatgttttct ccacgattta aataagtatc atttggaacg aaattttcct
    10501 ctcctactat attttcgaca acaggatgtc taccatttct tatatcaagt ttattatttt
    10561 catttattgc tggttttaca tagttattta tatgtgcaac tgttgcaagg gacacaaaaa
    10621 catctatatt agctatagtc ttagccactt tttgtattct atctatgttt ttatatattg
    10681 tatctcttat ctctacaaat atctcgtatt ctaaagattt aatcttttcc tctgcatgta
    10741 gtatcttttc ttctatttcc tttaattctg gagttatata tctttctgca ttactaagtg
    10801 tttgctttct tatatatgtc tcatctagct ttgcctgttt aaagttagct tttgttattt
    10861 ctatataata tccaaaaact ttattaaagc ctatttttaa tgatttaact cctgtttttt
    10921 ctctttccct gttttctatt tcctttacaa gaaaggctcc attcttagaa atctctctta
    10981 gttccttaag ttcatcacta aaatctgatt taattatgtt tccatctttt atggttatcg
    11041 taggttcttc tagaatagct tcatctatta aattgtatat atcatctaat ttatccattt
    11101 ctgaaacata ctcttttagg atttttgcat ttgataaatt tatagtatct tttaaattag
    11161 gtaacttttc tatcgaattt tttaagtgaa ttaactcttt tggtgttact ctctcaaatg
    11221 ctatctttcc acatattctt tctatatcgt atatattttt aagtatatca tttaggtctt
    11281 ctcttaatat aaagtcatct tttatttctt ctattacatc taatctattt tcaattttag
    11341 atttatttat caaaggttct tctacatatt ttcttaaaag tctacctccc attgctgtag
    11401 aagttttatc aagtacgtgt aataatgaac cttttttctt attccctctt atagtttgag
    11461 taagttctaa attagttcta gtaaacatat ctagaaccat atattctgat gaattgtata
    11521 tatttatatt attaatgtta gatgttattt gtttttgagt attgtatata taattcagaa
    11581 gaattgataa gcttgacttt attagacctt tatcatcaaa ctttagtttt tgtagataaa
    11641 catctggaaa atattctttt aatatattta tatccaaata gttatcacta aaactttcat
    11701 ttatgtatat attacttaca gtagctatat ctctaagatt ttctataaag tctaaatcat
    11761 ttataattat ttcagttgga tggatttttg caatttcttc aattacctta tcttcattta
    11821 aacatgttgc attagtttct cctgtactta tatcaacata agttagacct atattagtac
    11881 catccttata caaagataat aaataattat tctttttatt ttcaagtaaa tttccatcta
    11941 aaactgtacc aggagtgatg actcttataa cctctcttct aacaattcct tttgctgtag
    12001 atgggtcttc catttgttca cctattgcta ctttatatcc attttcaact aattttgata
    12061 tatatgaatt ggctgagtgg aaaggaacac cacacatagg agcacgttct tctaaaccac
    12121 aagcttttcc tgtcaatgct atttcaagag cttttgaagc tactaatgca tcttcaaaaa
    12181 acatttcata aaaatctcca agtctaaaaa acagtataca gtctttatat ctatttttta
    12241 cttcaagata ctgtttcatc ataggagtta atttattcat atctatttgc attatcaaac
    12301 ctccttcttt tctaattaaa tattatatca tagtagatga ttattattaa cacaatatat
    12361 aaaattttga catataacta aaaacaatcc aaaatgtata ctcacatttt ggattgctaa
    12421 gtttaatgct tattaaataa aaatattttt tttacaataa agatattatt tcttttttaa
    12481 gtttaatgat attttcaagg ttatcttcat ttaactttct actatctata acaaattctt
    12541 tctttactat tgatggtttt tttgaaataa cataaattct gtttgatagc attatagctt
    12601 cgtcaatatc atgagttata agaagtattg ttgaatttac ttttttctta acatctaaaa
    12661 gccatttttg catggatgtt ttagttaatg aatcaagtgc cccaaaaggc tcatctaaaa
    12721 gcattatgtc attagaattt ataaaagttc tcaagaagtt agctctctgt ctcattcctc
    12781 cagaaagttc tgaaggatat ttatcttcat atccgcttaa tccaaacacc tcaaaataag
    12841 gttttaccat tgacctagct ttactctttt tttctttttt taaaattagt ggtagtgaca
    12901 cattatctat tatagtttta tatggcaaga gtaaatcttt ttgatacata taactatact
    12961 taccatttat attcactttg ccactatcat aatctgtaag tttagttata atattaaaaa
    13021 tagtactttt tccacatcca cttggcccta atatagaaac aaactcacct tcataaacat
    13081 caatacttat atcttttaaa acttcaatat ctttataagt ttttgataca ttttctatag
    13141 atacttttac ttttttattg tggtaaaaat tcatttgtgt aagcatcact tgccttcata
    13201 tccttatcta ttaatttata ttcttttaag aatgatgtat agttgttcca tacactatct
    13261 ttcatttctc cccatcgtgg tgcatcatct ttgtacttgc ttgctaaata ttcttgactc
    13321 tttaaagcta gtttttcatc tacttcaggt gcatgtttta ctaaaatttt tgctgattct
    13381 tctggatttt ttattgcata ttcataacct tttgttgtag cttttaagaa ttttttagca
    13441 agctctggat tatctttaag cacagtttca ttagaaatta taagtggtgt ataataatcc
    13501 aatctctcat ctaaatcttt tactggtata aagtttaagt catatccaat taaatcagct
    13561 ttaactgcat cccaaccttc aaatatccat gcaaaatcta cagttttcat agctgcaaag
    13621 aaatcatctt gaccagtatt aactatcttt aacttattaa aatcagctcc atttttcttc
    13681 ataactgctt taaaaacagc ttcttctgat ggagagcccc aaccaccata agtttttcct
    13741 tcaaaatctt tagctgttgt tatattcttt tcttttggtg atgcaaaccc agaagtatta
    13801 tgttgtataa cagttgctac agcttttatt ggaagtggat cttcactagt ctttgcataa
    13861 gtaacttgtt cttgatagct tataccaaag tcagcttttc ctgttgctac taaagtttct
    13921 gctccacttt caggtggttg tactatttca acatccaaac cttcttcttt atagtaaccc
    13981 ttatcaagtg ctacaaataa tccagtatga tttgtatttg gtgtccaatc aagcaccata
    14041 gttacttttt tagaagaagt atctttatca ttgtttttgt ctttattgtt atttgaagaa
    14101 catccagtta ttgttgccaa tgtaaaaaca cttactaaac ctaatattcc taacttttta
    14161 aaattcataa ttgcctccct caaatacctt taatctatta atctatgtct tataacaact
    14221 ttttttacag cctgtacaat tcctacaaac attaaactaa atataactac taatatagta
    14281 gatgcaaata ctttatcaag tgcatatgca ctttttgacc taagcatata aacaccaagt
    14341 cctttcgttc cacctagcca ttctgcaaca gttgctgcca ttacagcata tgttgcagat
    14401 attttaagtc cagaaaaaaa tttatccatt gccataggaa atttaaggtg aatgaatgta
    14461 ttaactttat ttgagtccat agtcttaaat aaatttaaat aatctttatc aatattctca
    14521 atgccatcta caaaacttat taatatagga aaaaaacaag taagcattac catcaatact
    14581 tttggcattg ttccaaatcc aaaccatatc ataaagagtg gtgctataat tattgtaggt
    14641 atcatctgtg taaccaacat aataggataa agacattttt ttattattga tacaaaatcc
    14701 atcaatattc caattaccaa tgatattata attgcgacta taaaaccaag tattgcttct
    14761 cctatagtaa ccacagcatg catggataaa ttttgataat ctttaaaaaa cacattaatt
    14821 atatctactg gtgtgggtag tatatactga ggaacttcta aaactcctac catagattgc
    14881 caaagaataa gtataaacaa aaatgttgct attggatata tactatcttt gactttatct
    14941 atgatttcta agtttttcat ctatagtcag acctccagct ttttcatcta ctctagctac
    15001 tgttatgact ctttcacatc caagattaaa agggatttta tgtacctttt ttaataattc
    15061 aaaaacttca tcaaaatcac cttcaacagt agtgctcatt gctcctattt cacatttaag
    15121 accacttttt tcaatttcag caatacaagc atctactact ttatacatct cttcttcacc
    15181 tttgtaaggt cttagtggca ttactgctat gtctgcgatt accatttaaa tcactccttt
    15241 aaaaataatt aatacctact aggtatattt tgttttttat taaaaaattt tattactaaa
    15301 aagatattat atttaaataa aagaaaagtc ttatccaaaa taggataaga cttattttta
    15361 tcttaactgg tctccctaca ctggcattat ccaaacaggt tcaaagggtc gagataaaat
    15421 ctcctctcag cacattagct ccccgaaata tattatatct tttctacttg attatactac
    15481 acttatcata ttttaacaaa ttttttattt atattagata ttttatccgt tcaaaaatat
    15541 ctaatataaa ttgtacatta ttacaccaaa taaattatct taaaatggta ttttatcaac
    15601 atcttccaaa actagattaa ctgaattttc tagtttttat tttgctattt caagcatatt
    15661 tggatgtata tcaattccat acaaatattg tgctaaattt ctgttttcac tcatctaatt
    15721 tgcaatcgtt acagattaca gattagaaac agtttttaga ctctacttat ctttatctac
    15781 aaaaaatctt tcaataaatt cattaataat attcagtaat ctaaaaataa acctctatct
    15841 ggatttttaa gatacaaacc ttttaggaag tatcttttgt gataatataa aaattactcg
    15901 tcattatcat caaaatcctc agcaaccaac attttatata agaatcaaac tctataatat
    15961 aattatttta tccaatttat ttttgagaaa taaaatattt ttttaatttt taaatttttt
    16021 aatatgcacc ttgaaaaaag aaacgttttc ctatattatg gtaatagtag aataaaacta
    16081 aataggcaaa actagagaaa tttagtgacg caaagctata gggactaaga cttatgaaat
    16141 gagttatgtc agccagttgc caaagagata ttttcttttt gtttttatga atgtttttta
    16201 gggggatata tgatatatgt ttatggataa aatggataga tgtacacata tactaactgc
    16261 atatatatgc agttcacgcg attactgcaa ttttatagat acacaattaa atgattttat
    16321 actagaatat ggagagaatg tggtagaatc ttgtttgcat caagtgatgg tattggtaag
    16381 cagatataat taaagaaatt ttattttcta gaaaaccctt tttagtttta tctacgtttt
    16441 ataattcatt aaagaactaa ttaaaataag cttcattata tatttttcat gaagtaaaca
    16501 gttaagttta tctcatatac tgtttacccc aattacataa ttctaataat atagattcca
    16561 atgatttacc acgtttagta gacaaatatt caacttttgg aggaatagtc ggataagaaa
    16621 tcctcttaat aagtccatct ctttcaagat actttaattc ttgtgacagt atcttatgac
    16681 ttatatgaac aacttctttt tttaattgac tgtaacgtat tggctcttgt tttaaaatat
    16741 gccataaaat aattgccctc catttacttc ctatcacagt catggtaaaa ccaattgaac
    16801 aattaaaatc tttttgtctt tcttcaatat ttggaaattc ttcaaaatta ttatctatat
    16861 ccatctcaat cctctctttc aaaatagtaa gtatctaact aaaaagtgca ttcttgttta
    16921 gcgtactaat tcgtaatata atcttgatta aaaaatagct atgcacactc gtgactttag
    16981 tcatgggagg ttcagtgtag catagagcct tacataatac tactttttta gatgtatatg
    17041 tttaaatttt aatatagaca tatgttattt tattaatttt atttaaacag ataataataa
    17101 ataataattt atctcaagtt ttctatgtag ataaactaat ctaatgttta gaaaggatta
    17161 tataatatga ataaaaaatt tcgtctttat caagttgact cattacaaaa gaaaaattta
    17221 caggtaatcc agctggtgta attacaaatg ctgatggctt atctgaatca caaatgcaaa
    17281 aaatagcaag agaattaaat aattcagaaa ctgcttttat tttcaataac ttggctaaaa
    17341 atcatcaaga aaattatgat gtacatatca gattttttac accaactaat gaggttccta
    17401 tatgtggtca tgctactatt gctgcccatt atgttagagc aatagaaaac caattcaata
    17461 acaaaacagt atttcaaaaa actggtgctg gaatattacc agttgatatt ataaaaaaag
    17521 ataatgatta tgaaataatt atgacacaag gaaaaattga agtatctcca ccattacaac
    17581 aaacctatca aaaaagatta cttaatgcat ttggtattta aaggaagata ttcgtacaga
    17641 ttgtcctatt gccatatcat ctacaggaca ttcaaaagtt atgattggaa taaaggaatt
    17701 atcaacatta aatagtttat ctccaaattt atatgaatta tcgaaaataa gtcaagaaat
    17761 aaaatgtaat ggatattata tttttacatt acataataaa gaaactctac aagttcatgg
    17821 aagaatgttt gctcctgcaa ttggtatttc agaagaccct gttacaggaa atgctaatgg
    17881 acccttaggt gcgtaccttg tacattataa agtaatacct acacccaaca cagagtttat
    17941 atttgaagca gttcaaggag aagcaataaa acgcaaaggc aagatgttag taaaagtaat
    18001 tattttagat aataagccag ttgaagtaaa aataattgga aaagctgtaa ttgcattctc
    18061 aacaaacata gaaatctaat tatagattcc ttctaagtaa atttttgaac tttttaatac
    18121 taatttaata acaaactaat ttatatacaa tcaaattaat ttttttatta tttgttaata
    18181 tatatttatc attatattat ataataatat agatagttac tatatcttat aattagataa
    18241 atcataatta tatattattg ttaaaactca attatataat ttttaataat attattttag
    18301 gaggtaaaaa tgataaacga tattaaaaat aaattcaaaa attacaaacc atatataaat
    18361 ggatacaaga atatgaagag agcatctgtt ttaattccaa tagtagaaat aaataacaca
    18421 cactatatat tatttgaagt tcgctcaaaa aatttgaagc atcaacctag cgaaatttct
    18481 tttccaggtg gtaaaataga atcaggtgag actccatatg aagctgttat tagagaaact
    18541 tgtgaggaac ttggaacttt tagtgacaat atagaagtaa tatcaagtct tgacctcctt
    18601 ataacaccag taaagtttat catacatcca tacttaggat atataaaaaa tattaataat
    18661 ttaaatataa acaaggatga agttgaccat acttttttgg ttcctataaa atatctttta
    18721 gagaatcctc caaatactta tagtaatact gtaaaagttt ttccagatga aaatctacca
    18781 tatggttcaa ttccaaacca aaaagattat aaatttgaaa gtggaagtta tcctattctg
    18841 ttttataaat ataaagatta tgtaatttgg ggaatgacag caaaaatact agaaaacttt
    18901 ttaaattttt tatcagaata acactcataa taaattatca aaatttttac ataagaaatt
    18961 tataaaagtt tctaaattta acaattctaa aatatcaata actatatttt gtagcacttt
    19021 tttattttat tattgtttga atatttgatg gttttcaatg caatttcaac ataaatacta
    19081 tatattagtg tatactgttg atgaattaaa gtatgataat ctatttaata aagtatgaag
    19141 taaatgattt taatgtgcct ttatggtaaa attactaata agtaataaaa ttaattaaaa
    19201 tatatggagg tccttataat gtttgctgta ggatttgttg ttataattgc acttgccttt
    19261 ttcattttaa gtgtactatt atttaatgga aaagccagta tgctactagc aggttataac
    19321 tctatgagta agaaagaaaa agcacgatac gataaaaaaa aattatgtag aagttctagc
    19381 attgttactt ttattgtctc tataatgcta tttattatgg cgtttttggg atatagaata
    19441 gagagtggtc aaatggacga aaaaaaaatg gttccctttt ctataatatt tataatagtc
    19501 atactttcca gtgtattttt taatatcctc tactctaaca aaaaatgtaa aaaataaata
    19561 gttgtaagtt gagcagttaa ttataaaaga ttgactgctt tttcatgtat attgactact
    19621 cttattaaat attttaacat ttaaaaatct atgtaaaaat aatgaatata gtacaaactt
    19681 ctaataatga ttttaccttt gtggttacag tccactatat ataatttaat atgataacag
    19741 ggaattatta atgacaacta agtaaacttt tataaaatat aataaaacaa aaatagatgt
    19801 acaatgaaat tatatcttat atcaaattta tttttattaa tagcaaaaac ttacattagc
    19861 ataacatatg acaaattcgc ttaaaataaa aatttttaat ataatttgtt ctatagtaca
    19921 tctattttga ttagtttaca taattttatt attttgtaca atattaatta tttactaata
    19981 tcccatttaa tgaaaaagtt ctaggttcag taattttgac cataactaat ttaccaatta
    20041 aatcatcatt tccaccttcg aaatttacga gtttattttg tctagttcta ccagcaaact
    20101 tattttcatt atttttactt cttccttcaa ctagaacttc aactattcta tctttatatc
    20161 catcatttat ttctgcagaa atcctattta cagcttctaa caccctatta aatctatcat
    20221 gctttatatc ttctggtatt tgattttcca ttttagcagc aggagttccc tgtcttttag
    20281 aataaataaa tgtaaaagct gaatcatatc taactttttc aaccacatct aaagtgtcca
    20341 ataaatcttc ttctgtttct cctgggaaac caatcattaa gtctgtagaa aaagcaatac
    20401 ctggaacttc ctttttagct ttttctatta tttctaaata atattccttt gtataatgtc
    20461 tattcatttt tttcaaaagg ctactgcttc cgcattgtat tggtagatgt aaaaactcac
    20521 acaccttatc acaatctcta attgcgtata ttacttcatc agatatatct tttggatgag
    20581 atgtcataaa tcgaaccctt tcaattcctt ctatatcatt cacttttctt aaaagttctg
    20641 agaatgaaac tggattttca agtgtcttac cataagaatc tacattttgt ccaagtaaag
    20701 tgatttcttt cgttccattt gcaacaagct cttttatctc gttaattata tcttcaggag
    20761 ttctacttct ttctcttcct cttgtgtatg ggactataca atatgtgcag aaattattgc
    20821 atccatacat tatatttaca aatgctttta attcaaattt tctattactt ctaagacctt
    20881 ctattacttc tccatccaca tcccatacat ccactaacat tttgtcagaa tttattgatt
    20941 ctgtaagtaa ttgcggaaat ttatatagat tatgtgttcc aaatataagg tctacatgtt
    21001 tatatttttt tcttaattcc tctacaacat gtggttgttg catcatacat ccacatacag
    21061 ctattttcat atctggattt tttcctttta gatgttttaa ttgtcctaag ttaccatata
    21121 cttttagctc tgcattttct ctaactgcac aggtgttata tattattaaa tcactttctt
    21181 caaccatcat tgacatttgg tatcccatct cttctaacat tgaacataat ttttctgaat
    21241 catgttcatt catttgacac ccaaaggttt gagtaaacac gagttttctc tttccagttc
    21301 tgttgaagta ttcttcattt tgtctgtgta tttgttctat atatttatct tgttcttgta
    21361 ttttctctat aggtattgtt acttgttttc ttttgctcac gtctattcct cctagttaat
    21421 ttcttatatt acacataacc ttaattatat caaataagaa aaatctttta aagatattat
//
LOCUS       DAEHWO010000073        21218 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEHWO010000073 DAEHWO010000000
VERSION     DAEHWO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21218
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.073"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            128..1138
                     /locus_tag="KNP54_003018"
     CDS             128..1138
                     /locus_tag="KNP54_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBF0893883.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            1274..1762
                     /locus_tag="KNP54_003019"
     CDS             1274..1762
                     /locus_tag="KNP54_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0893884.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            1938..3866
                     /locus_tag="KNP54_003020"
     CDS             1938..3866
                     /locus_tag="KNP54_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0893885.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            4043..4453
                     /locus_tag="KNP54_003021"
     CDS             4043..4453
                     /locus_tag="KNP54_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBF0893886.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            4475..4777
                     /locus_tag="KNP54_003022"
     CDS             4475..4777
                     /locus_tag="KNP54_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBF0893887.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(4994..5686)
                     /locus_tag="KNP54_003023"
     CDS             complement(4994..5686)
                     /locus_tag="KNP54_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBF0893888.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(5712..6899)
                     /locus_tag="KNP54_003024"
     CDS             complement(5712..6899)
                     /locus_tag="KNP54_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0893889.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            7235..9112
                     /locus_tag="KNP54_003025"
     CDS             7235..9112
                     /locus_tag="KNP54_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0893890.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            9469..10875
                     /locus_tag="KNP54_003026"
     CDS             9469..10875
                     /locus_tag="KNP54_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBF0893891.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            10903..11751
                     /locus_tag="KNP54_003027"
     CDS             10903..11751
                     /locus_tag="KNP54_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0893892.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            12412..13104
                     /locus_tag="KNP54_003028"
     CDS             12412..13104
                     /locus_tag="KNP54_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0893893.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            13101..14036
                     /locus_tag="KNP54_003029"
     CDS             13101..14036
                     /locus_tag="KNP54_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0893894.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            14184..15107
                     /locus_tag="KNP54_003030"
     CDS             14184..15107
                     /locus_tag="KNP54_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893895.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            15091..15861
                     /locus_tag="KNP54_003031"
     CDS             15091..15861
                     /locus_tag="KNP54_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893896.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            15871..16653
                     /locus_tag="KNP54_003032"
     CDS             15871..16653
                     /locus_tag="KNP54_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893897.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            17030..17566
                     /locus_tag="KNP54_003033"
     CDS             17030..17566
                     /locus_tag="KNP54_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBF0893898.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            17598..17987
                     /locus_tag="KNP54_003034"
     CDS             17598..17987
                     /locus_tag="KNP54_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBF0893899.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            18024..18410
                     /locus_tag="KNP54_003035"
     CDS             18024..18410
                     /locus_tag="KNP54_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBF0893900.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            18537..19979
                     /locus_tag="KNP54_003036"
     CDS             18537..19979
                     /locus_tag="KNP54_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBF0893901.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            20276..21091
                     /locus_tag="KNP54_003037"
     CDS             20276..21091
                     /locus_tag="KNP54_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0893902.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         7833 a         2476 c         3898 g         7011 t
ORIGIN      
        1 attttttaac atacaaatga ttttatgaaa aaaaacaaga ctcaaaaatt tttatattct
       61 ttgatagaat aaaattgaga gtaaatttat tgaattttat aaaatttata aggggtgagt
      121 ctaagatatg catgaagata aaaatgatat atttgaatca atagatactg aggattttga
      181 taataaaaca gaagaagaat gtttagagct agtaagaaaa aatggattga atttaatata
      241 cataaaaaat caaacagaag agatatgtct agaggctgtt agacaaaatt gtaatgcaat
      301 aaaatgtgtt cagaatcaga cagaaaaaat atgtatagaa gcagttaaac aagattggag
      361 aatgttagaa tttgtggaag agccaacaga agaaatttgc atgttggcta ttaaccaaga
      421 tggaacagca ttaaaatata tagaaaatca gacagaggag ttatgcttaa gagccgttga
      481 aaaaaatggt gcagctttgg agtatgtaaa agaacaaaca gaagaaatat gtatagaagc
      541 agttagaaac agcgaatttg gattggcaag agtgaaaaat caaacagaaa aaatatgtat
      601 ggaagcagtt aagcattgta gctataatct aaaatgggta gaaaatcaaa cagaagaaat
      661 atgtatggaa gcagtgagac aaaatgggct tgatttgaaa tttgtaaaaa atcaaacaga
      721 aacaatctgt ttaagagcag taagacaaaa tggaatggca ttagaatttg taaaggaaca
      781 gactgttggt atatgcttaa aggcagtaag acaatatgga atggcattaa aatttgtaaa
      841 ggaacaaaca gaagaaattt gtacagaagc tataaaacaa gataaaagag cacttagttt
      901 tgtaaaagga gataaggaaa aatataaggc tctatatgat aataatgaac catttgcaaa
      961 gagatatgtt agaaatgtaa tagaaaaaga aaacagagca ttgattaaaa aaggagaaga
     1021 aaatgcaaaa atcaaaattg caggaaaact ttatgataga ggcatgtctt ttgaagatat
     1081 atcagatata gttgagattg aaataagcaa gttaaaagtg agtttaggtg ttttttaaag
     1141 taataaatgt aggtgttttt tatgggaaat agttaataaa aaaataatcg actagctctt
     1201 tgtaggacag caaaattagt gatataattt gatgtataat aaattatttt tattagataa
     1261 gggggaatta aagttgaaga ttacagtatt ataccaaaca agaagtggaa acacagaaag
     1321 ggtcgctaag ctgatagaag agggcgctaa aaaggtggat ggagtagatg taaagcttat
     1381 gagacttgat aatattgatt tagattattt aaatgaaagt aaagcagtaa tatttggaac
     1441 acctacttat ttagcaaata caacttggga agtaaaaaaa tggtttgatg aagattcaaa
     1501 aaaagttaat ttagctggaa aattaggagc tgtttttgct acatgtgatt atatatgtgg
     1561 aggtccagat gttgcgatac ttactatagt aggacatttg atggttaaag ggatgcttgt
     1621 gtattctgga ggtggttctt taggaaagcc atttatacat ttaggacatg tacattcaat
     1681 tgaaggtcca gagttacaag atgagaaggc tataatattt ggtgaaagaa ttgctactaa
     1741 ggcaaaagaa ctatttgctt aatttctata tgcatagtaa tgattagagt aaatttaggg
     1801 ttttaatgga gatttgaagt aaaagttata aaataaaaaa ttttccataa aattactcaa
     1861 gatgaattat aatataatta taaataaatt atattattaa aatatttaaa atcaaacgtc
     1921 aatagcgagg gaagtttatg gtatggcata tagaatatga gattttttct gcaattatag
     1981 ttattttttt aatggtatac ttttttagaa gtaaatttat acctacttta caaaacaaaa
     2041 tatattgtgc acttttaata ttctcatttt tatttataat ttcaaatatt ttaggttcat
     2101 tttgtctaaa taatatagac aaaattccaa tttttattac ttttttattg aatcagatat
     2161 acttattgtt attgccaata ccagcagcac ttgtatcatt ttatgttatg gctattattt
     2221 atcaagatat aaggtatatg aaaaaaagat tattattttt atctatacca cttataattt
     2281 gtataatctt atctattaca aatcctttta cgcatattct atttggattg tcaaaagaaa
     2341 caggttatat acgaggttgt ggatatgttg caacttttgc atcttttttc ttttatgcaa
     2401 tatattcagc atttttatct tttaaatata gaaaagcaat gcatgaatca aaaatatggg
     2461 ctattagagg ttttcttata gtttcaattg tggcaattat cttacaggca atttttttac
     2521 agtatcttct tacaggaact gcatgtgcat gtagtttact tttgacatat ctttctatgc
     2581 agaatcgagg tcttattatt gatgacctta ctggtgtact caatagacaa tcttttattc
     2641 aagagctaga tttgaatatc aatactgaac aatcaggatt tattattaca attgcgcttg
     2701 atgattttaa gtttatgaat gaaacttttg gaacaaaaaa tggagatatt gcactaaaag
     2761 aagttggaaa atatttgatt cagatacatg atgtaaacca tgtatataga atagggggag
     2821 atatattttc tattgttgtc aatagtcaat taggtataga accagatgat attatcagaa
     2881 agatagaaga aagatttaaa aagccttggc tagtagaaga gataagtttt aatttagcaa
     2941 ctagtattgc tgttgtttat tacccagaaa atgcagaaac gacagaagat gtaattgttg
     3001 ctatagattt ctctatacat gaagcaaaac gctctgagtc aaggcgagtt gtttatgcag
     3061 atgcgtctat aagtgaaaag ataaagaaga aacatgttat taaaaattgt ttaaaagaag
     3121 cattaaaaaa tgatgggttt gaagtgtact accaacctat attttctaat agcaggggca
     3181 ggtttacttc agcagaggca ttacttaggc tagaacacaa agagttaggt tttatacctc
     3241 ctgatgaatt tattccaatt gcagaacaaa caggattgat taactcaatt ggattagtag
     3301 tctttgagaa ggtatgtaga tttatagcta gtgatgagtt tgaagattta aaattggata
     3361 atatagctgt gaatctttct gtagtacaat gtatgcaaaa aaacttagct gatgatttac
     3421 tttatcttat gaataaatat aatgtatcac caactaaatt taaacttgaa attactgaga
     3481 ctgtggctat gggctctttt aatataatta aagaaacaat ggaaagatta attgatttag
     3541 gtgttaagtt tgcacttgat gattttggaa ttgcttattc tggagttact aatatgcttt
     3601 ctttaccatt ttcagtaatt aagttagata agagtttgat ttggtctatg aatgaagata
     3661 gtaggcataa acttacagtt gagacgatta tagcacttat aaataaattg aatatgaagg
     3721 ctgtagcaga aggtgttgaa accattaagt gtgctgaaga tttaatagct atggagtgtg
     3781 aatatttgca agggtattat ttttctaaac cagttccaga agatgttttt aaaaatttgt
     3841 tgaaagaaaa tacttttaca agttaacacc ctttattttt ttaattacaa ctttgttcat
     3901 tgacactgcc agcgatatat tataaaatta acacaataat aaatattaaa tttattatac
     3961 atattattaa tattaattaa tggagtaaag atttattata tattttattt aattatccta
     4021 aagtgagaaa ggaagatgtg acatgaataa aaagaaaata ttagtgccaa ttgatgggac
     4081 agaaagaagt atgcattctt tggaatttat aaaaggaata tttaaaaaag atgaagttga
     4141 agtagaaata atgaatgtaa aagaactagt atttattgat ggcatatccc tggctgaaga
     4201 gataaaaaat tctgaaaatt taggaagaag aatcttggat aaagcagcag agataatggg
     4261 agagtatgat gttaaagtac attttacttt tggatatcca ggagatgaga taattagaaa
     4321 agcaaaagaa gataatgtag attttatagt tatgacaaaa tctactaaaa aaggtcttac
     4381 aagaatgata ggttcagtaa cagcaagtgt agttaaacaa gcaaaatgta tagtgatgat
     4441 tgtaccggag tagaattaga aaggtatttg aaatatgaat aaaaagatag tagcagtttg
     4501 tgaaagtgaa agaagtttaa attctcttaa gacagctgca aatgatttag gatttgattt
     4561 agtttatgaa attcaagaaa atgataatat aaaaaatgaa ctttctattt atgatataga
     4621 agatgcatcc atagtgttat ttgttacaag tgattctata gaaagcatag agaagattga
     4681 tagatttata gatagagaat tttatgaagt tgatccaaag tatataatag aggatgcaaa
     4741 atctatagta agtgaaattt taatagactt aaattaatcg tgggtgtcgc actaagaata
     4801 gagcgacgcc tttttatata ttttacacaa gaaataaaga ggttgtatca aaatatagat
     4861 aagagtcttt ttcattgttg aaatgatgaa aatatatttg atttcataca aaaaagagta
     4921 cctcataact aaaaagttca ctttgagaca ctccattttt atatgttagt tgcatttaag
     4981 gtaaaataga agtttaatca tgttgaaata actgaattac atcttctaaa tgattgtaca
     5041 ttgatgtata acctaagtaa gagtctttac tatcaaatgc aatcattatc ttgttatggt
     5101 ggctaatcat atccttgaga gaatttctat atttaaaacc aaagtattgg ttagaagaaa
     5161 ctgttttagg tattaactca taatatttta taaaaattgg attatgagaa gctaaaatta
     5221 tctctttgtg aaattgcaag tcagcatcat aacattcttc tatcaaacca tgagaaacct
     5281 tatccaattc ctctattgac tttaggtaag tatattttat tttttgaagt tctttagatg
     5341 tagcatttaa aattgctagt ttagtagctt cgctttcgat aagttgtctt gctcttaaag
     5401 attctacata aaattcttgt atgttatgat ttttatagat ttcaccatca tcaaataggt
     5461 caactttttt aaatccttca actataggac ttgaataagg cacagctcta agtattcctt
     5521 ccttacagag tatatttatg gcatttctta caggtattct acttatgtta aataggtcag
     5581 caatctttct ctcacttggt aatttactat taattttaaa agttccattt agaatgttta
     5641 atttaatata atcaataatt ttttcagtgg catttaagct tttcataaaa actcctaaac
     5701 atataatttt tttatgattg tattatatca tagttaagag ttaaatctac ttttttataa
     5761 tatgtataag acaggataga ggccaaaata gctataatag ccaagataaa gtatccatat
     5821 tgtattgaag tatattccga tattttacca actatcattg gaaatacaga cattcctata
     5881 gcataaattg cttgaaaaaa acccattgca gtagatttct gatgttttgg tacatttttc
     5941 atagactcgc tagtaaggta agaaaggagt atacctgtag atatacctgg tagtacttgt
     6001 agtacaaata ttatattaat attttttatt gttggaacta aaaagcaata ggctgaaact
     6061 aaaataaaaa ctaaaggaat ccaaaatttt ggtccatact tagtacaaaa tttagtagaa
     6121 gcaaagccag aagaagcaac agcacacacc atgtaaaata tagaagatag acctatgagg
     6181 gtagaactag aacctaagtt tttaagaatt tgagtagtaa atgacattgt tgtagacatt
     6241 tgaataccct gttgaattaa tgccataaag gaaaaaaata caagtctttt atccttgcag
     6301 atagataaat attttttaat tgatattttt tcaggtattt ttttagaatt atgatttttt
     6361 atatttaagg ctagaatcgt tccaataact gaagacaata cactcatgat acataaggct
     6421 gtcattccta atttttcata aaataaagta ctcataacaa atccaatcaa cattcctaga
     6481 ttgtttacca atattatcgt acttgtagct ttttgttgat gttctgtaga aaaaaagttg
     6541 gtatagtgaa ccatgtaaga aatccaagtt gatgatgata ttccagataa aatgttagct
     6601 ataagaaaac cattgcctcc aggagaaaag actcttataa gagatgctaa accagcaaag
     6661 aaaattccag acagtataaa tattttatgt ttatttatgg aatcagcaaa tactccaaca
     6721 ggaagcctta ataaacattg tgatattcca tatgcaccta ttattatacc aatcatattt
     6781 gtagatacat tacatgcact taaatatgga ttttggaaag gtatatatac atattgtgaa
     6841 aaccagaaaa atgtaacaat agaaagtaaa agtaattttt gattagatat ttttttcata
     6901 ttatcctcca tgtggtattt ttataatgca aataatatac catttagatt ttttaatcaa
     6961 gtactttctc tattaaaaaa aatttaaata tataattatt atttacaaaa aaattatact
     7021 ttatagttga attaagaaaa cgcttatgat actataaagt taacaaattt gaatatataa
     7081 cagtagacgt gttactggta atgcaggcaa gatcgaatca atttttatag attatctata
     7141 gagtactatg ggtataatct atttatttgg ttcgattttt ttgtttaatt ggccataaaa
     7201 caaaaagcct atagttgaaa atggaggatt ttttatggat tataaaaata tagctcaaga
     7261 aattctacta aatgtaggag gaaaagagaa tgtaaatgaa gtgactcatt gtatgacaag
     7321 acttagattt aaagtcaaaa gcgcttctaa agtgaataag gataaattat ctaaaactga
     7381 aggagtaata actgttgttg agagtatggg tcaaatacaa gttgtaattg gaaataaagt
     7441 aaaaaaagta tatgatgagg tcataaaaat tgtacctcaa tcaaataaca taggtaaaaa
     7501 gaatgaaagt caagaaaagc aaggtataat taattctata ttatcagcag tagctggtat
     7561 atttacacct acaatacctg ctatagcagg ggttggtatg attaaaggta ttttatcagt
     7621 tcttgctatg tattatatga ataaaaatgg agtagatata aaagaaacgc aaagctatat
     7681 tatcttaaat gctatggctg attctatatt ctattttatg cctattatac taggatatac
     7741 tgcggctaaa gtatttaatg caaataaaat aatatctatg gtattaggag ctacactttg
     7801 ttatccaact tttactgctt tgatggcagg tgaagaatct gttagatttt taggattggc
     7861 agtaacaaaa gctacgtata catcatctgt tattccaata attattgcta tatgggctct
     7921 ttcatacgtt gaaaaagtat tagaaaagta tatacctgag gtaattaaaa taataatggt
     7981 tccaacttta tcattggtag taatgttacc tgcaacatta tttttatttg gaccaatcgg
     8041 aatttatata ggaaatgtca taaacttttc ttataagtat atttatgaat taagcccagc
     8101 attgtgtgga gcatttgtag gtgggttatg gtgtgtgtta gttatatttg gtgctcatag
     8161 agcattatta ccaataggta taagtgatgt tgctcaaaca ggaagacaaa atttattggc
     8221 gtttgcagga gctgcaaact tttcacaagc aggggctgct ctaggagtat tctttaaaac
     8281 taaaaatcaa ggactaaaaa caatttctat gtctgcaact ataacagctt tatttggtat
     8341 aactgaacct gcaatatacg gtgccaatct tagattaaaa aaacctatgg tatgtgccgt
     8401 aatatgtggt gcatttggag gtgcgataat gggaatgggt ggagcttatg gtaatgcatt
     8461 tgcaaaccaa ggtgttttaa ctatacctgt atatgctgaa gcaggtgcat taggtttctt
     8521 aagttatcta ggtggttgtg ctatagcatt ttttggttca gctatttcaa cttatctagt
     8581 tggatttgaa gatttggaag agtcttctaa taaggaaaat tcatctataa aagtagaaac
     8641 gaaggatggt gttattgata taacttcacc tgtagagggc gaatgtatag aattgtcaga
     8701 agtaaaggat gatgtatttg cttcaaaagc tatgggagaa ggtatagctg tgttacctac
     8761 aaaaggagta ataacagccc ctactgattg tgaagtagct tctttatttc caacattaca
     8821 tgcaatagga ttaaaattag ataatggagc agaaatgtta atacatgttg gaatcaatac
     8881 agtagagtta aatggtaaat actttacaaa acatgttaat caaggagatt tagtgaaaaa
     8941 aggtgataaa cttatatcgt ttgatataga taaaataaaa aaggctggtt atgatgtaac
     9001 tacgccagtt atagtaaaca atacatttga ttttgggcaa gtagtttctt gtaaatctag
     9061 ttatgtttca accaatgata atataatttc attagtatta gctggtaatt aagttaattt
     9121 gactagagat aagtaaattg atttaaaagg aaataagtaa atcaacaatt aaatacatct
     9181 aaaagtaagt ttattgcaat gaattgttaa agaaaataat taatatggag taaatctatt
     9241 gcaatgaagt aacaaagaaa ataattaata tagagtaagt ttattgtaat gaattgttaa
     9301 agaaaagagt taatatagag taagtttatt gtaatgaatt gttaaagaaa ataattaata
     9361 tagggtaaat ctatctcaat gaaataacaa agaaaagagt taatatagag tgaacttatt
     9421 gcaatgaatc aacaaagaaa ataatcaata taaaaaggag aaatatttat gaatacagga
     9481 tttccaaaag actttttatg gggagcatca tcttctgcat ttcaagtgga aggagcttgg
     9541 gataaagaca ataaaggaaa aaccgtagcc gactataatt cttttaaaaa gtctcattta
     9601 caggcagata ctaaagtcgc atcagacttt taccataatt atgaagaaga tattgaatta
     9661 atgaaagaat tagggatgaa aacatatcgt ttttcaattt catgggcaag aataatacca
     9721 gatggtgaag gagagataaa ccagaaaggt ttagaatttt ataataagat aatagacaaa
     9781 ctgatagagt gtgatattga gccattcgta actttatacc attttgacct tccatttaaa
     9841 ttagtagaga aatataatgg ttgggaaagt agagaaactg tctatgcttt tgaaagattt
     9901 gctaaaatat gctttaagca ttttggagat agggtaaagt attggcaacc tcataatgaa
     9961 cagaatttaa ttgttagagt ggaggagaga attaatatat atgatgaaac agattcatgg
    10021 aagatagata aaatgcgtgc tcagatggat tataatcttt gcttagcaca tgcattagca
    10081 gtcaatgcat gtcatgagat gataaaagaa agtaaaattg gagcagcagt atcatcatct
    10141 gtaacatatc ctcttacttc taagccagaa gatgtatatg cagctagaat gaatgataat
    10201 tttaaagtgt actatatgct tgatatgcat cattatggag aatatccagg gtattatatg
    10261 aagtatcttg aaaaaagaaa tatagttcct cacatggaag atggggataa agagatactt
    10321 aaaaaagcta aaatggattt tatagctgta aattattata ggacaaattg tgcagaagct
    10381 ttacctgaag attcacaaca tccatttgga ttaagagaag gaactgttga ttttagtatg
    10441 tatggactat ttaaaatgtc aatgaatcct aacttagagg cttctgagta tggagcagca
    10501 atagacccat caggtcttag agttgcctta aatgaatatt ggcaaagata tcacttacct
    10561 gttataataa cagaaaatgg tctaggagct aaagatatat tagaagatgg aaaaattcat
    10621 gatgactatc gtatagacta tttaagaagt catataaatg catgtaaact agctattgaa
    10681 gatggtgtag agatgattgg atattgtcca tggtcattta cagacctttt aagttcttct
    10741 caaggtttta ataagcgtta tggacttgtt tatataaata gaactgacca tgaagtttta
    10801 gatttaaaaa gaatcaagaa agatagtttt tactggtata aagaagttat agagaacaat
    10861 ggaatagtaa aataaacata aatatatatt gagggtttta gtatgtacat tacaaaggta
    10921 ttaaataatt cgttgctact tgcaaaggat gataatgatg aagaaataat attgatgggg
    10981 aaaggcattg gccataatta taaggccggg tctgagttaa ataaaaaaga tatagaaaag
    11041 atttttgttc ttcatgatga aaatataaaa aagagtatta tacaattggc aacagaaata
    11101 gatgcagaat attttggtat agctcaaatg ataattgcat atggaataga aaaatataac
    11161 ttaaaactta tgaaccatat atatttggcc ttaactgacc acattgcctt tgcagtgaga
    11221 cgttttaaag aaggtataat gattgaaaat cactatttgt tcgaaatcaa ggaatttaat
    11281 ccaaaagagt atgatatagg aaaatatgct attactgttt ttaaggaggt tcttggttta
    11341 gacctaccag aagaagagat tggtaatata gcaggccatt ttataaatgc acaacaagat
    11401 aatccttata gtgatagaaa taagagaagt gctaaaattg taaatgctat tttgcaaata
    11461 gttcattatc acttttctat tgtatataat aaagagtcat tttattatag gagatttgta
    11521 atgcatctaa aggccttttc acaaagattt ctggctaatg aaccatcaag agaaaaaata
    11581 gattttatat atgagcaagt tcaaaaaaat tgtaaggaag agtatgaatg tgtgaaaaag
    11641 gtaggagctt atatgtataa ggaatactcc agagaattac caagacaaga ggagttatat
    11701 ttgatgattc atattcataa gattttagga gaattatgcg aaaatagtta gaatatctta
    11761 atatgctagt aatattataa aaaattaaaa attaactgca ctttaaatat gaataattgc
    11821 attacttaag ggggttgtct taaaattgat ttttttaatt aaatttgaag ctcaactcct
    11881 tttttaaacc tttatatcat tacaacttta atgtttatac gactgtactt tagatgtata
    11941 tctacttttt acatttctca acatgcaaac ctaccatttt ttgcagtatg ttaattgaaa
    12001 taaaccattg agttaaccct aaatttattc tggacttata ggaatagttc caaagatact
    12061 ttaaaatatt ttctggaata attgcttatt tcacatatgt tttattgtga tgttttgatt
    12121 taataaattc ttcaactctg tatatagtaa atgtattatc atgtttgttt tattcaagca
    12181 cacttataat acgcttgatt ttttcacaat gatgaaatat actaatgggt gttataggta
    12241 taagaatcgc attacacttg aagaagtaag tgataaatga ggtataaatc ctcatatgat
    12301 aaactactat ttcattgagg aacatattct aagtgatgtc aagatactac aatatgacta
    12361 aattcctagt gataaaaaag tctacgaatg agtgtagaaa ggggaactaa gatgaataaa
    12421 gttttaatta tagatgatga taaagatctt tgtattttgt taaaaaagag tatttcaatt
    12481 gaacagattg aagcaaacta ttgccattct gggagagatg gactggttga actttcaaaa
    12541 caagattatc agttagtagt tctagatgtg atgatgccag gtatggatgg ttttgaaact
    12601 atggaacaaa tacgaaaata tagcagtatt cccatcttaa tgctgacatc aaaaagcgat
    12661 aattacagca aagtgcatgg attgcgagct ggtgcagatg actatctaac caaaccattt
    12721 gaaattacag aatttactgc tcgtgtactg tctttaatcc gacgttacac ccgttttaat
    12781 ccaaaaaatg aggagccaca gcaactttct ttcaaaggtt tgttgattga ccttgaccag
    12841 catacagtta ctaccaatgg cgaacctatg ttgcttccac ccaaggaatt tggtgtactt
    12901 ctttactgtg caaggcatca gggtaagatt ttgacaaaac agcagattta tgaagccgtg
    12961 tggggtgagc catatgtata tgatgacagc aatatcatgg ctattatcag tcgcctaaga
    13021 aaaaaaattg aactagaccc atcatctccc atctatttgc aaacaataaa aggaattggg
    13081 tatcaattca acacggaggt atgaaaatgg atgaacaaac gataattctt ttcttactct
    13141 tgctgtcgat tggtctactt tttctttcca tatttgcttt ttccaagctt gggcatattt
    13201 acaagcgcct aaaagatata gaggagatac tggctgatgt acaaattgga gacgaaaatc
    13261 gtaaaatact aattaagcca tgtgatgtta tggctccatt ggtttatcag cttaatgaga
    13321 ttgtctacga ttatgaaaat aagttacttt ctctgaaaaa gtcggataaa gctagcaaac
    13381 aacttatgac aagtttatct catgatgttc gtacaccatt aacaactctg attggttatc
    13441 tggatgctgt acacagtggt atagttatcg aacaagagcg ggaggaatac cttgaaatcg
    13501 ctaggcgtag agcctacgac ctcaaggatt acattgatgt tctttttgac tggtttcggt
    13561 tgaactctga tgaatttacg ctgtcaatag aatctgtgga aattgcagag ttgtcacgca
    13621 atattttgaa agactggatt cctatattcc atgaaaagaa actgaatttt gaaattgata
    13681 ttccagaaaa tcgactaatg gtaaacctcg acccagatgg atattcccgt gtggtcaata
    13741 atctggttca aaatgttctt gctcacagta aggctcggca aatcaagatt accatgagtg
    13801 aggattccag aatggtatta ctccgtgttg aggatgatgg tgttgggatt gccagagaaa
    13861 atttaccaca tatttttgag cgactgtata agtgtgataa aggacgttca gaaaaaggaa
    13921 gtggtcttgg tctatctatt gtcagtcaaa tggtggagcg aatgggtggt caggtttccg
    13981 tagaaagtga gattggaaag tataccgtat ttacagtgag cttaccatta atataaaatt
    14041 gtttttcccc catgtgacat gtatacacat ggggattttt tgtaagttat aaagttgcaa
    14101 ggttaataca aggttgttgc aaggttaatg taagattgag gtggtatgat aactttaata
    14161 aacaaaggag gcttttatta tttatgaata atttaattat tgaaacaaaa aatctcacta
    14221 agcaatatgg tgctcaaaag agcgtttcta atttgaatat tcacgttcag aaaggtcgca
    14281 tttacggatt gctaggaaga aacggtgcgg gtaagacgac aactatgaaa atgttattgg
    14341 gtctaacaaa accaactact ggagaaatta aaatatttgg tcaggacatt cacaataacg
    14401 agaagaagct tcttcctcga attggatgtt tgattgaatc accagggttt tatcctaatc
    14461 tgacaggaac agaaaatctc aaaatctttg caaggcttag aggaatacca aaaaaaaatg
    14521 cagtagaatc agcactggat gtagtcggtt tgccaaacaa tgacaaaaag ttattttctc
    14581 aatactctct tggtatgaaa cagaggttgg cgattgctct tgccattatg catgacccac
    14641 aactgttgat tttggacgag cctatcaatg gacttgatcc tattggtatt gcagaagtaa
    14701 gaacgtttat tcgtgatctc tgcacagaac gaggtaaaac tattttgatt tccagtcaca
    14761 ttctttctga aattgccttg ttggcagatg acattggcat tattgaccat ggtattttgt
    14821 tggaggaaga aagtcttgcc caattagaag aaaaaaacag taaatacata cattttgctg
    14881 tatctgatgc agcacaggca gcaaggcttc tggaaaccca acttaacctg aaaaatttca
    14941 aagtagcaga taattacaat attatgctat atgatacaga tgtttctgtt gcagaaataa
    15001 atcgtgcttt cattctaaac aacattgagg tatcagaatc tcatttatgc gaagatactc
    15061 ttgaagatta cttcaagaaa gtaacagggg gtgaaggaat tgcttgatat aatttcatgt
    15121 gaattttcaa aactcaagcg gttaaaattt atactgattt ctattttagg tgcttgctta
    15181 tttccaattc ccgcaacaat tttgattgca aaggacaact tgccctttga gcaattgttc
    15241 aaattagttg tcaattttgg atattttttg ctattaccaa ttgtattaag tattgttgct
    15301 agccaactat tttttataga aagagataat gatgtattaa aaaatcttgc aacagtgcca
    15361 gtgcaaaaag gaaaactggc tctggcaaaa ttggctgtgt tgctgtttat atcattgttc
    15421 tactctgttg cagggttagg agctactatc attggaggtt tcattgttgg aatagtagag
    15481 ggggttgctg taaaattagg aatgagcatt gcttttggaa ttatgttttt tgttactgta
    15541 cttcctgttg tggtactcat tgtatatttc aatcgcagct atattttttc tattatactt
    15601 tcttttgtat atgctatttt caattttagt atatccttaa atattatcaa ttttgaacca
    15661 aataacccaa tattaagtgt attacctgct cctgttataa tgcgttggtg gatggcattt
    15721 tggggagatc ccactggcga atacacggca cttagacagc catatttgct ctcaactcct
    15781 gcttgtgtag gtattttatg tttgataacc attatagcag tcctgctgat ttgtatgata
    15841 tacaaaaagc aggagaatta ggaggtatct atgcttgata taattactac agaatttcaa
    15901 aaaataaaaa gatataatat tctatggatt ggtgttgttg ctgttctgtt ttcagcacta
    15961 ttggcagttt ttcaggttgt aagttcacac ggcagtgacc ctctaacgta tgagagcttt
    16021 gcaaacggag ttatctggaa taatttcagt cttagttttc catttgggat tacacttatt
    16081 ggaggatatc ttattaaccg tgaatataca gaccaaacct taaaaaacat cctaactgtt
    16141 cctatttcat tacgcaaatt gctagtggga aaattaattg cggttggagg aattactgta
    16201 ttgttaagtc ttttcagctt cttatgcaca tttattttgg ggttgttgtt ttgcaatatc
    16261 aatatatctg ttacactcgt tgtaaaatcc ttagttcaga ttttgtctgt taatctgtat
    16321 tgttatgttg ctgttttgcc gattattgct tattttggtc gtaaacaaaa tgcatttctg
    16381 acgggtgtag ggattgcatt tgtatacggt ttttgtggtg tgtttgttgc tggaagaaat
    16441 ctgacagact tttatccaat cacagcaggt cttggtctag ttggatacaa caatggtgct
    16501 ggtactgttt atcagccact tatcggtgct atgactttga ttgtaattct aatcttgaca
    16561 actattctac ttgtatttac acctaattat gataaagtta tgaccatatc taagaaaaaa
    16621 gggataaagc ataaaaagta ttctcataaa taacataaat attgtttcta ttatttaagt
    16681 tgctagacag tgaaaagaaa aaatctgtcg tacagtgtct atatgctcat gtattcaaga
    16741 agctacagtt ttgatttttc ataactgtag cttctttttg tatttattaa atcacgacta
    16801 tcataatact tgcaataggt atagcgacaa gagagagtac tgtcatatgt gttttatata
    16861 ttacattaag tatattctaa aatatatgtt ttaaataata tatttgaaaa taggaatatt
    16921 taaataaaaa aaataatatt atatatagtt gacaaaaatt ggcaaatgag ataatatata
    16981 aatatagaaa tagtaatcat tactattatt aaaaagggag gaattaatta tgaacttaaa
    17041 aggaactaaa acagaaaaga atttaatggc aggatttgca ggagagtcag aagcaagaaa
    17101 taaatataca tactacgctt caaaagcaag aaaagaaggt tataatcaaa tagctgctat
    17161 atttgaagaa actgctaaca atgaaaagga acatgctaaa ttatggttta aacttttaca
    17221 tgatggtatg ccttcaacag aggaaaattt aaaggatgca gcagcaggtg aaaactatga
    17281 atggactgat atgtatgcaa aatttgctaa agaagctaga gaagaaggat ttgacaagat
    17341 agcttattta tttgaagctg ttggaaaaat agagaaagag catgaagaaa gatacttaaa
    17401 gcttttagaa aacttaaatg aaggaaaaat atttaaaaga gatgaagaag ttgtttggca
    17461 atgtcaaaac tgtggtcatg tgtatgtagg tactgaagca ccagaaaaat gcccagtatg
    17521 tgaccatcca aaagcgtatt tcaatataaa agctgaaaat tattaaaaat tatcattatt
    17581 aaaaaggaat gttaactatg aaattttcta aacaacgaga actgatttta aatgaaatat
    17641 taaataatcc ggttcatcct actgcggatt acctatatga aaacttaaaa aaagataatc
    17701 caaatttaag cttaggaact gtgtatagaa atttagctca gctaacggaa catggcttta
    17761 taagaaaggt tagtattcca gggtatccag atagatttga tggtcgaata gataatcact
    17821 atcatatcat atgtgaagta tgtggagagg tatacgattt agaatccgaa gttcttaata
    17881 atttacaaga attaatatct gaggagacag acataaaaat aacatcttat aacataagtt
    17941 ttaaagggat ttgtaataat tgtaaaaggt gtagccaagt aggttagttt tcaaattcta
    18001 aaaataatta atgaggtgag tttatgtgta gtgaacaaaa attttttata tgtgagactt
    18061 gtggaaacct tgtaggaatg atacaaagtg gtggtgtacc tattttctgt tgtggaaaac
    18121 ctatgaagga acttgttcct aatacaacag atgcagcagt tgaaaaacat gtacctgtaa
    18181 ttgaagtgga tggaaataat gttactgtta aagtaagtag cacaactcat ccaatgacta
    18241 aagaacatca tatagcatgg gtgtatctta tgactgaaca aggtggtcaa cgcaaatgtc
    18301 tagcagtaga tggagaacct gtagttaaat ttgctttgaa tgatgatgat aaagtgattt
    18361 ctgcctatgc ttactgtaat ttacatggat tatggaaggc tgaactgtaa tatttaaata
    18421 aattgagtca aaaaggaggc tataaatgta ttttcataca aatagcctcc tataaattta
    18481 tataaattca agttttaatt ttgtttaatg tcaatataat ataaggagaa aataatatgt
    18541 caatttataa atgtagtgtt tgtggatata tttatgatga atctaagaat gataaaacat
    18601 gggatgaatt aagtgaagat tgggaatgcc ctgtatgtac aaaaggtcgt agttattttg
    18661 gaaagataag tactgtttac tatgaagaag atgaaaagat agcagaagac atagttgaag
    18721 atgaatctaa attaaatact gaaaaagagg gagatttaaa ttacttaagt acatatttaa
    18781 gaagagatga tgaagttgag aaacatatgg atataattca cgaaatggct gttacaggaa
    18841 aatctataat agaacctatg agaactaaac taccagtaat ttcttgggat gatattttaa
    18901 ttatgggtgc tcaattaaat ccattacctt taaatgagca tgatgaagta aatacaacaa
    18961 caataatagg aaaaaaagca aagaaaccta tgattataga aaatccagtt tatatttccc
    19021 acatgtcatt tggagctttg tctaaagaac taaaaatagc tttagcaaag ggtgcagccc
    19081 aaaataagac agctatgtgt agtggtgaag gaggtatatt accagaagag aaggaagctt
    19141 catacaagta tatttttgag tatgtaccaa ataaatatag tgtaactgaa gaaaatctta
    19201 aaaattctga tgctatagag ataaaaattg gtcaaggaac aaaacctggt atgggaggtc
    19261 atcttcctgg cgaaaaagta actgaagaaa tagcaaaagt aagaaataag cctgtaggtc
    19321 aagatgtaat aagtccatct tgttttgagg aaatacaatc caaagaagat ttaaagaaac
    19381 ttgtagatga acttagagaa gtttcagaag ggcgtccaat aggtgttaaa atttcagcag
    19441 gtcatattga aaaagatatg gaatttatag cttatgctaa acctgatttt gtaactattg
    19501 atggtcgtgg tggagctact ggagcaagtc caaagttgct taaagatgca acttcaattc
    19561 caacaatatt tgctctttat cgtgctagaa aatacataga tacacatgga ttagatatag
    19621 atttggttat aacaggtggg cttcgtatat ctactgattt tgctaaggca attgctatgg
    19681 gtgctgatgc agttgctatt gcaagttctg ctcttatggc agcggcgtgt caacaatatc
    19741 gtatatgtgg ttctggtaag tgtcctgtag gagtagctac tcaggatgag gaattgagaa
    19801 aaagattaca tatagaaaac agtgctaata gagtggcaaa ctttttaaat gtaagtttag
    19861 aagaacttaa gacttttgct agaatttctg gtcataaaga tatacatgat ttaagtgttg
    19921 atgatttata tactgttaac tctgaaatat caaattatac aaacatacag catgtataga
    19981 ttgaagtttg aaactattag attttagata gctataaaag taaatgataa atatatttta
    20041 taaaagagag tgtcttaaaa tgaacttttt agttcataag tcactctttt ttttatgaag
    20101 ccaaatatat ttatcatttt agcaatgaaa aagaatctta tctctttatt ttgagataga
    20161 ctccttctat ttatgaaaat taaagatatt aaattgtaaa atattctgtg atgtcgtact
    20221 attaaactaa agattctgta ctttaaagta aataaaaatt taaggagtga ttattatgga
    20281 aagattgaag atacaagttt tagttgacaa taatacttat attgatagat actttgttgg
    20341 agaaccagca gtaagctatt atattgagat tgatggaaat aggattttgt ttgactcagg
    20401 gtattcagat gtattcatat caaacgctga aaaattaaat atagatttag gaaatttaac
    20461 tcatgttgtt ttttctcatg ggcataatga ccatacaaga ggtatccagt ttctagaaaa
    20521 taggtatgat ttatctacag ttgaacttat ttcacatcct aactgtttta tacctagaaa
    20581 acatggagag aaaagcatag gagctccatt ttctgctgag gaaattaaaa atatttttat
    20641 gtataatcct aaggataagc catttaatct aagtaagaat tgtgtgtttt taggtgaaat
    20701 accttctata aatgattttg aaaaaagagc taaaattggt aaatgtaaaa taggagattt
    20761 gtgggaagat gattatgttt tagatgattc tgctatagtt tgtaaaactg ataaaggtat
    20821 ttttattgtt acaggatgtt ctcatagtgg aatttgtaat atagtagagt atgctaaaaa
    20881 ggtatgtgga gatgatagag ttattggtat actaggtggt tttcatcttt ttgaattgaa
    20941 taataggtta gatagtacaa tacaatattt ggataaagaa gaaatgagaa tgttgtaccc
    21001 ttgtcactgt gtttctttta aggtaaaagc gaagatgaat gaaatattga atataaatga
    21061 agttggagta gggctgacca taagtatata gtatttgaaa gtatataaga tttaagttga
    21121 aggttaaaaa gatattttct atagaaaata tcttttttgt tacgtttatt ttaagagaaa
    21181 tcaatatact tttatatgaa atattgtaaa aaaattta
//
LOCUS       DAEHWO010000074        20791 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEHWO010000074 DAEHWO010000000
VERSION     DAEHWO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.074"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(102..638)
                     /locus_tag="KNP54_003038"
     CDS             complement(102..638)
                     /locus_tag="KNP54_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBF0893903.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(656..1969)
                     /locus_tag="KNP54_003039"
     CDS             complement(656..1969)
                     /locus_tag="KNP54_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBF0893904.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2324..2764
                     /locus_tag="KNP54_003040"
     CDS             2324..2764
                     /locus_tag="KNP54_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBF0893905.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2948..3136)
                     /locus_tag="KNP54_003041"
     CDS             complement(2948..3136)
                     /locus_tag="KNP54_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBF0893906.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            4158..4553
                     /locus_tag="KNP54_003042"
     CDS             4158..4553
                     /locus_tag="KNP54_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893907.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4596..6695
                     /locus_tag="KNP54_003043"
     CDS             4596..6695
                     /locus_tag="KNP54_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBF0893908.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNTSTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6920..12130)
                     /locus_tag="KNP54_003044"
     CDS             complement(6920..12130)
                     /locus_tag="KNP54_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBF0893909.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSMDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12145..14640)
                     /locus_tag="KNP54_003045"
     CDS             complement(12145..14640)
                     /locus_tag="KNP54_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0893910.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIES
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15301..15588)
                     /locus_tag="KNP54_003046"
     CDS             complement(15301..15588)
                     /locus_tag="KNP54_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893911.1"
                     /translation="MRLNITKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNIFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15608..15883)
                     /locus_tag="KNP54_003047"
     CDS             complement(15608..15883)
                     /locus_tag="KNP54_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893912.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16518..16697)
                     /locus_tag="KNP54_003048"
     CDS             complement(16518..16697)
                     /locus_tag="KNP54_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893913.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16982..18457)
                     /locus_tag="KNP54_003049"
     CDS             complement(16982..18457)
                     /locus_tag="KNP54_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0893914.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
     gene            19488..20666
                     /locus_tag="KNP54_003050"
     CDS             19488..20666
                     /locus_tag="KNP54_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0893915.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
BASE COUNT         7053 a         3551 c         2248 g         7939 t
ORIGIN      
        1 ctcttttttc tgtacttaca tataatatta aaactcttta ttttttaata tatattttaa
       61 attttctttt ttaataaatc tttttctttt aataaatcta tttaattttc ttcttctata
      121 tcagagccaa agggaatcca tgcattacca aactctttat ctttaaataa ataagctaat
      181 ccagttattt gcttcaatct aagaatttca tcaacttcca tacccaggtg ctttgatatc
      241 cattcatcag attttccaat ttcacaaagt tcagttataa ttttactcat taaatccaca
      301 ttatgagaac ctcttgcacg attgtgtcga atagtacttg ccattctttc atcaagagat
      361 ttatcaatta ctgaaacagg aagaagtcca ttttctctat catatatatc ctcattttca
      421 agcattactc tatatctatg aaaaccatct acaataatat acttatcctt ttcctcatta
      481 taataacaga caattggcat tgtataccca tcttctttta tacttttata caacaactgc
      541 atttctggtg gggctactgc atttggatta tagtcgttag attctatctt ttcgattggc
      601 actgcgatga ttccatatac aggactttta tattccatag catcttaact cctatctaat
      661 gaattttttc atatttcttc ttaatatatt ccgttctaat tctctgttct tttgtaggac
      721 caaatcccat aaatctacac atatggtcat tttttaaaat acaataacac attcttttcc
      781 aacttggtat atctttggta aatttaatat catccgtatc atcaggtata tcatccaaaa
      841 atatgactct actcttttta tcttttgtat gatttgaaac tccatttaat tctattttat
      901 aaccttttct caacaattca cgtataacta tttctgacaa accaccacct gtattctgcc
      961 aaaactcaat agatgttgaa aattttttaa tatagctatt ccttatattt tcaggtaagg
     1021 tatcaagcaa aaaatatgtg aaacttttcc atgtgtgtcc atatggcaat ttaacactac
     1081 gatatcccat agcttttgtt ttgccataaa tagaagtaaa attaactcct tgtactctag
     1141 caaccaattt cacccataca tctgggtcca atattctgta taaatttaaa ctctcttttg
     1201 ctgaatcatt aaaaggtgat gccactctca tttttcttgg agctactcca gctttataga
     1261 ataagtcata aattttatta tagtcatagt caaatttata gtgtgctaac catatatctt
     1321 ctatttccca atcatatata ggagatgccg tccagacatt tttaaattcc ttagttatcc
     1381 agcactttcc tttatatcca tgctgtttat tcacaataga acaataacgt tgtagagatt
     1441 ctgctgctcg tgttcctaat aagcaaacaa cttttgcacc ttcatgtata tctctaatcc
     1501 atctaccaaa ttgttttgcc aaactttctt gtctcatttt atatttataa taagtaaaag
     1561 gattattttt ttgatttatt atgtattctt tgactggcat ttcccttacc cataactctt
     1621 ctttctcatc atcccatgga taccaataca tttcataatt tcctacagca gttcttgtag
     1681 ccattggtaa acacacccaa tatggttcaa tatcttcaat attatcttca aatacttttt
     1741 caacatattc agtagtcaaa ctatattgag cctcaaaatc ttgatgaaat actcctattt
     1801 tggaacttat attattcttt ctcttataat ccaaaactaa atttagcagt aaaccactat
     1861 cttttcctcc gctaaaagat acatagatat aatcaaattc attaaaaaga taagaaagtc
     1921 tttcttgaaa agcttcaaat acatcggatt ctaaatatct cttatccatt tgaattatcc
     1981 cctttcaatt agaagtttat aaaaccttac aatgcaatat tattatgctt ttttagcagt
     2041 aatcagcata aattatacat tatttaaata cacaaatcca actaactaca tataattata
     2101 atgtaattat acttttgtat tataaactat attttatcat tattttacat ttttttccaa
     2161 tatatataaa tatcatattt ttctattagc taaaactaat tactttatat ttctacgtat
     2221 tagtataata atacataaaa acttgaataa tgcataaaaa cttgacatac tgttgtcata
     2281 attactttgc tataattaaa agtaaaaatg gaggtaaatt ctaatgtatg aacgtatgct
     2341 tgataaaagc aataaaccct gtttgtccca aataatagaa tatataggta aagatggata
     2401 tgcacgattg tgtaagttgg aaacttactt gaaaactcaa tataatttat caagagaact
     2461 tcgatttcct tttggaaaca attatggttg gggttacaaa tatagccata aatcttttca
     2521 tttattttat gctttttttg aaaaaggtgc atttactgtt ctgattcaga taggtgacaa
     2581 gcaagttcca gcagtagaaa aaacgttggt agctttgaca ccaaaagcta aagaactctg
     2641 ggtcactcgt tatccttgtg gcaataatgg aggctggatt aagtatcgta ttttagaaga
     2701 tgcagactta cttgatatta ttcaatatat aagagcaaaa aaatctccac ctaaacaaaa
     2761 ttaactttta ttttttgtga tttaaatata gtgtatataa attccattct ttccatatta
     2821 aaaaataata taaaaaatat ctattagtat aacttattta gtatgtctta ttctactttt
     2881 tacagataat taaaaagttt tatcataaat aaatcataac tagacatcct agtaaatcaa
     2941 aattaattta ttctttttta ttcgaatttt tgataatagt ccctatacat atgccaatta
     3001 tcattccaaa aattagacca taacacattg taatacctac atttccttta gaaataccta
     3061 tagcacaacc tatagccatt ccaagtatca tgcctataaa catacatata ataactaaat
     3121 tgttgttttt attcatagtt tttctccatt caatatattt taaattgcct agctcgcctt
     3181 cttagcttaa aacaaagaaa tataaattaa ctttctttca ttctaatatc tgcctgtata
     3241 aatgtcaaac aacacatttc ttgtcataac ctcctctttt tgaagtaagt acaatctccc
     3301 agacgcaata atatcaattt cctaaaacca tttaagtaac ttttatattt acataatatt
     3361 tacaatcata aactatattg ttattcattt atacatcata aacactccct cctaatcatt
     3421 attatactta aaataatgtt catttataat aatatatcta acgcacttta attgaaaaaa
     3481 ctaaaacttt gcctttcatt cccatatata aataagtata ctttttgatg ctctattaca
     3541 aatcaactaa attaattgat ataaattatc attttctgtt gaaaatacca ttcgcacatg
     3601 ctatacttaa ttgcataaat ggtaataaat gtcatatgat tttacaaatc tattaataac
     3661 aattattact tttactgtat tttaaagttt ttggactaaa tatcaagaac tttctaaaat
     3721 acaaagtaca aaaaatttat ataagttata aatttatatg aactagataa gctcaaacaa
     3781 tatgttatgt ataaactgtg tagtattcgg ttataaattt atataaatta tataagctag
     3841 ataaagtatt acctcaacta tataagctag atatataaat tgcttatata agctagataa
     3901 gaattatttc aactatataa actacatata taaattacat acataagcta gatatataaa
     3961 ctgcatatat aagctatata agaattattt caaccatata aactacacat gtaaaattca
     4021 tataaattta ctaatataaa tcaaataaaa ttactaaact ctctaaacta attttgtaaa
     4081 acatactcta tttttaacat ttgttacctt atacataagt acaaacaaaa tctaactaaa
     4141 tgaaaggata atgtaaaatg aatattttaa aaatgaaaaa aacagggata tttttaggag
     4201 gagtactttt tggtactgta ggtgttaaga tactttcaag tgattgtgtt aaaaaaactt
     4261 gcactcgtgc aacagcagga gcattgaaag ttaaagattc tgttcttgaa acaactacga
     4321 aaattcaaga aaatgtagaa gatattttag ctgaagcaaa agaaatcaac gagcaagaag
     4381 acttatctac atctaaggta aacgttgtac aagatactct taaatgcgaa caagaagttc
     4441 ttaaaactga aactataaaa actgtagaag atactaattc taatagcatt aaatgtgaag
     4501 aaatcaaaga taacgtaatt gaagaaaaaa atagtacttg tacaacagaa taaatttaat
     4561 gattattatg attaataata tcaggaggaa gtaaattgaa tttttatata aaacacgaaa
     4621 taagaggtcg tatacgcttt gacttacaac ttggcaaatt aaacaacaag cagtccgata
     4681 ctctcttata ttatttaact tctataaatg gtattaccaa agcaaaagtt tacgatagaa
     4741 ctggtgatgc agtcatttat tacactggtg aaagagaata cataataaga gaaatcacta
     4801 aattcagttt taacaatagc aaaatagaaa acctagttcc tgaacatacc agcagggaat
     4861 taaacaatta ttatagagac aaattagcaa ataaactgct agtcaaaagt atctccaaaa
     4921 tattttttcc aaagtcctta agattttttt taattggact tcattctata aaatatttta
     4981 aaaaaggtct ctcttccctg ctaaataaaa aaatagaagt ttctgtttta gatgccactg
     5041 ctataggtat ttctattttt agaaaagata tcaatacggc tggttcagtt atgtttcttc
     5101 ttggtatcgg tgaactatta gaagaatgga ctagaaaaaa atctatagac gacttggctc
     5161 aaagtatgtc actaaacatt gaaaaagtat ggttaagaaa aggtgacact gaaatcttaa
     5221 ttccaatttc agagataaag gaaggagatt tagtaagtgt aactatggga aatatgattc
     5281 cattggatgg agttatagta tcaggagaaa caatggtcaa tcaggcatca cttacaggtg
     5341 aatcccttgc cgttaacaaa aaagaaggct cttacatata tgctggaact gtaatagagc
     5401 aaggcaatat tgttatgtgc gtcaaggaaa aagctggtac tactagattc cagaaaatag
     5461 taactatgat tgaggaatct gaaaaactaa aatcttctgt agagagtaaa tttgaacatc
     5521 tagcagatac attagttcca tacagctttt taggaagtat attaacctat gcaattacta
     5581 gaaaccctat aaaatcactc tctatattaa tggtagattt ctcttgtgca ttaaaactct
     5641 ctatccctat ttcagtacta tcagccatga gagaatgtaa caataacaac attactgtaa
     5701 aaggtggaaa attccttgaa ggtgttgcat gtgcagatac tattgtattt gataagacag
     5761 gcacattaac aaaagctcaa ccaactgttt cagatataat tacattccaa aattataata
     5821 aggaggatat gttaagactt gcagcttgct tagaagaaca ctttccacac tccatagcaa
     5881 atgcagtagt ttacgaagct gaaaaacaag ggcttagtca caaagaaatg catacagagg
     5941 tagaatatat tattgctcat ggcatttcaa caaaagttga tgataaaaag gttgtaatag
     6001 gtagcaaaca ttttgtattt gaagatgaga agtgtactat cccagacggt gaggaggata
     6061 agtacaacaa tctatcagat gagtattcac acctatttat ggcaatatca ggtaaattat
     6121 cagcagttat ttgcataaat gaccctttac gaaaagaagc aaaatatgta atttcaaatt
     6181 taagagaatg cggaataaaa aagattgtga tgatgactgg agatagcgaa aaaacagcta
     6241 aatctatagc aagtaaagtt ggtgttgatg aatattattc agaagtctta ccagaagaca
     6301 aagccaattt tgttaaaagt gaaaaactca aaggtcgcaa agtaattatg attggtgatg
     6361 gaatcaatga ttctcctgct atttcagaat cagatgtcgg aattgcaatg agtgaaggtg
     6421 ctgaaatagc aagagagatt tcagatatta ccatatcagc agataatttg aataatttaa
     6481 tcgttttaaa gcagattagt aataagctta tgaaaagagt tgatttaagt tctaagttta
     6541 ttattggctt taatttaggt ctgattttac ttggtgtagg tggatttgtt agaccaagta
     6601 catctgcctt tttacacaac acatctactg tcggaataag tttaaacagt atgacaaatt
     6661 tattggaaaa caccaatact tataactacc attaatctcc attacataaa acatatgata
     6721 taaaaaattt ataattcatc tttttaaaag aatatgtctt aaaattagct tttttctaat
     6781 caaaattata taaagcatac tttacaaatt ttaaactcaa cttatttcta ttttttacaa
     6841 aaaaggagat gattcaaatt ttcattttga aacatcccct tttgtaaatt tctttaaaat
     6901 ttatatatta attatatttt caaccaataa ttgtattttc aaccaatctt tcttcatagc
     6961 attttaaatc attttgcttt agataattaa attcagactc tacataaata ccacagccta
     7021 ccaattcaat tgtcaaatta ggtatatttt cctttagtat actagtctgc tcataaataa
     7081 ttctttccaa taaatcaact tgtaatatag aaaaatgctt cataatctcc ccatcactat
     7141 ctatatcttt cttgatttca taccaactct ttgacaaaat tcccttcaaa tcaatatacc
     7201 ctagactcct caatatatct atactatcgc tccatgcata cttactaggt ttatcaaagt
     7261 atgattctag tttcttcttc tgctcatttg taagtgaatc ataagaaagc ttcttattaa
     7321 aatgtgcctt caaagaaatc ttagccatag aatatggact tctaccagag tttaatcctg
     7381 catttttgaa cttttcaatt cctttatctt ctactgaaga ccatattgag tttattgaat
     7441 ctgaatcatt gtatttaata tcaagaccat gtgtaatatt tatatagttt tgtggaaata
     7501 catattgata atagacatct tttttatcat catatagaga gaagtatcca ctatcatata
     7561 aatgaatatg cacctttact tttaaactat cctctaaaat atttcgtcta aggttcggga
     7621 tatttgcata catggttaca tattttatgg catcaaagtt tttatttaat ggaacttcaa
     7681 aactaatttc atctcctgtc aaaagctttt tcacttcttc ttcattacaa tcatatagag
     7741 aatatgtatt ttcaaatccc acacgtgatt tcccatctaa actgcctgtt aatgctacct
     7801 tcaaaatatg gttatctgtt ttttgccatt ggtaagcatc ttggtcaaga aactctctaa
     7861 tctgtctatt ttgctctttc gcctgattta taacctcgtt ttcatcttct gtaatcccta
     7921 catggcatct atttaagata tttactatat tgcttccaaa tgggaatgtc catagttgaa
     7981 aagctgctgc ctcaacctga cacaaatatc taacctgatt taattcaatt tgatggataa
     8041 gttttttctg atattcattc atctgattac cactatctga catttgataa atcaattctc
     8101 ccattgcaag attatctttt ttcttatcaa tcttatcagt aatgataatt tgagtttcca
     8161 tcatatcctg tactttttta aatattatag aaatctcctc tgagttttcc atttttaagc
     8221 ttccaaactt cgtgcttaat tcagttaaaa cttccttcat ctttaattta cttatctcat
     8281 tttcaaaaat atcttgattt ttaactgtac tatcgaattt ttctacaaat ggtataacag
     8341 attctttcaa agttttatct ttaaattcca ccatttgagt attcaattca tctaatttct
     8401 taatattatt ttctttatct ttaattgcct ctttaactac ctctatttta ctctcaaaac
     8461 tagattttac attaagacaa ttattaacac cactaatcgc agtatttata agagaacaag
     8521 cagaacttcc aatactcaat gcatttttaa ttttagatgt cttttgctgt ctttcaatag
     8581 cttgtttact tttctctagt gcagctaact tatctttttg ctgtttatta ttgtaatttg
     8641 cctccaacat acctatttct tttttctgga tttttgtgta aatttcctta tactcgcttt
     8701 cacttaaccc ctcttttgct ctttgaatat cgtcagcttt gtctgcatag ttatcatcat
     8761 ctatagactt aactataatc tccttaattt ggtcaaattt agttcttctt tcttcatcaa
     8821 cacctgccaa attataagtc attttatcta aagcattttt tctatcttca cttagctgtt
     8881 ctccaagtac aaatctcata ccatcagaat ccaatttaaa atctgaaaaa tcaaccatcc
     8941 tgttagtcca ttggtattcc tcttctttag ctgaaagatt ttccttcaaa gattttgcac
     9001 tgtcaaatgc ccctagacaa gcttgaccaa caccactaaa tgcagtcagt aaactcaatg
     9061 cgctttgtat tccagaaaga attaactgtg ttttcatttg ttcctcaagt tttgcctgtt
     9121 tcttttttag ttcctctatg tcttcttgtt catcttcttt catctttata atttcttgaa
     9181 tcaacaggtt catttttgca ttaacagaaa gcattttatt ctcaagttca ttttttaaaa
     9241 cctctatttg ttgatttcca gattcaattt gagttaggat actttcctta tatgtattga
     9301 aatatccttc ttttaactca tctttctttc cttgttccaa ttctcttaag gtcttatcca
     9361 gatagtctgt caaagaacga atatctgtaa cacgatttcc tccaatttca ctttcttcaa
     9421 tcatctgcac ataaaatgct gtcttctgct caagtgcaaa taaaatcata ctccattcgc
     9481 taaaattctg attttttcct acaaaagatt ctattctatc agactgcatc aatttattta
     9541 taaggtattc atagatttcc tttgcctctt tataaaattc tttctttata ttcatgtcat
     9601 ccatagaaag tactgcttta tttttcttct caaaactata gtacttctga agtatttctc
     9661 tatttaattg catctctatt ttctcaactg cataaaaaat ttcataaata tgtgaaaatt
     9721 ctaaaatatc agcttctaaa attcctactg cacacaacag tctaagattt ctataacctt
     9781 taattccaga aaaaccaaat ctctcgaaaa attcatagaa gaatgtatct attgacaaag
     9841 aatactcctg ctttaacaat tccttttctt ttagtgcatc tccagagtga ccggcttttc
     9901 cctctgctcc ggctgaacct gaatcttcac gtttgctaat tgtccagtcc ttatgttctt
     9961 cataaagagt atttaatttc tctccatcat ctgctgcttg cttctgattt aaagcatgat
    10021 taaacacata tctatcaaaa taatagtagt ttctatcact attatccatt ggaggagagg
    10081 tacctatata tcttattgtt tcttcatata tacctctaat tccaccaaga cctcctgcac
    10141 caccagctcc tccagagcct ccttttcctg ctaaaccatg atttccatct tttttactta
    10201 tagcactttt taataaagga gcttttccaa ggagataaac ctgtccagac ttgcttccaa
    10261 gacctgcatt tccaccatta cctcctgtgc ctccagttcc accttgtttt cctttttctg
    10321 cttttacaac atagtatttt gtacctttaa cattagcaaa ttcttttgac tcttttttag
    10381 aacctatttt agcatttgcc ccagcttctc cagttatccc tgtatctcct ttttttccat
    10441 cttgtccatt tccaccacgt ccaccatcta cgtaaagttt aagttctcct cttttttcta
    10501 tttctttaaa agataatatg atatcacctg aagtacctgc attattgcca tttcttccat
    10561 tcattccgtc gtaaatagaa ctttctccaa ccaatttttc tgcatcctta ccagatacgt
    10621 tgattgaata agtcccttct ggtatatgta atttttctgt aagtagtaca atattcttac
    10681 ctgagaagac ttctttctcc atattacagt caattttcaa ctcacaatct ccatacatat
    10741 atatagatga caaaatatta agttgataac cagatattat tttagtcaaa tccgataaat
    10801 tcactttagg tataggaata tatatagaaa gtacattttc tttctcatat gattttatat
    10861 atgtacaact ttgaatcttc tctatcctat actctgcatc ttcaagcttt ttggcttctt
    10921 cttccctata ttcttcttct gctatccaat atttgatatc ttttaatgta tcttctaaag
    10981 tattttttag caatgatttt aacaactcac ttagaccaac aatatgagtc tcactacagt
    11041 aactatttaa ctctaaaaga agacgtgttt cttctaatat attcactttc tgtacgccat
    11101 caccatatga aagttcttgt acaaactcca taagctcttt catattatta gtcctactac
    11161 ataaatctgt atacatctta tctaattgaa tctttttatc ttttagacta tttatagaag
    11221 atagaatgga aatagaatct tccatacctt ttttaacact ttctatataa ggaactaaaa
    11281 gtttttctag gtctttatag gttacatcaa cagctttttg tatttctatt ttacaagaag
    11341 ctgtaagcat caatcccaaa tctgtttttt caaatgtttc aggtagattt ttcatttcat
    11401 ccaacaactt ttctggctgt ttatctagtg gattacataa tttaatagat acaccatctg
    11461 ataatgctac atttaataag tacactaatt ccttacaacc gtcgtaatct ttctcttgac
    11521 tatctaagtc ttcttttgct ttttccaata tatttcttat tttttcttct gttacattac
    11581 cgattagtgt tttaggtatt ttattaataa gaaagaagaa attttcttta tactttgcat
    11641 aatcaccaag catatctttc aaatttttgc ctgtttctat caataatgta tgtctagagt
    11701 ccagtaggga ttgatagtct aagataacta ccatcccttt cacctttgaa gatgtggaaa
    11761 tagtttccct tacaagcata gcaccagcaa tcatatactc tgctccacgg ttgtcaaaaa
    11821 aacctgggca atcacataat gaaaaatctc tatttgcaat atctacaact tctggacata
    11881 aagtcttaga atatacacca tttccaattt cgacagctga atcttttgca gttatatata
    11941 tttgtccagt ctcttcatcc gttttttctt ccatcacaca gccttttaaa taatttatac
    12001 aagtactctt tccaacgcct gaagcaccta ggaataacaa aattgacttt tcttttaagt
    12061 catattttct aagctcgtct cttccttctt ccaaaaggtt tacgatttca ctataaagtt
    12121 tatttgccat acatccatcc ctttctatat ttcggaacaa tagccttgat atttttcttt
    12181 aataagattc tcttctacct ttgaaacagc tgttgataac ttagtatttg gagcattaaa
    12241 tcctccattg tctcctctat ctccatattc agcgtattct cttgctggtc ctgttttacc
    12301 ttcattccag cttccaccac taaattctat atgatattta attatactat ctaacttata
    12361 atcccaactt gtaaaatatc ctgtatagta tacagtctta tctataccac ttggagaaaa
    12421 tgaaagtgta ttatatccgt gatagccacc acttcctcca tatccaccta aacctggtct
    12481 accatttgga cctgcttctc catctttcac tgttatatca caatgattaa ttattctatt
    12541 tttttgttcc tctgaatctg aaatgaagta aatattacct ttcttaccag catttccacc
    12601 tcttccagca tttccaccag ctccaccttt ttcacctttt ttgccacttg tacctttttc
    12661 aaaataccct ttaaacatct gtccgtggaa ataacttgta tatcctgcat cagctccatt
    12721 acttccagaa gctcctgttt caccattttc tccatctatt cctttagaac catttcctcc
    12781 atttgcaatc agtgttagac gataatttct aatttcttct ttaatatata agtaaatatt
    12841 acctgcatct ctaccatctt caccattttt cccatacata gaattatcta caagttctcc
    12901 gctctttcca cttacattaa tttttacatt actacctaca tcaagattgt tagaagcaag
    12961 aataatattt ttctctgatg caaagttcat tccaaggtta tcatccatat aaatagtatc
    13021 tttagcaaag aacataaaag tagaaacatt gtcatctact tttctatttt tgaaatattc
    13081 caatacactg ctaattacta agtttggaat taatgctctt atttcaatac ctttcttatc
    13141 attaatatta attgttttta ctataaatgg atttaaaatg tatttaccaa taaattctct
    13201 aattatctca ttaccttctt ctccatatgc acttaatctt gttatactgt cttctaactc
    13261 ttcattttgt gtaactgtaa catttgtcaa aattgaatta aaatcactta cactatatac
    13321 ataatccttt ttatttgcaa cttccattaa tttttctcta tttggtaatg taaatacctg
    13381 tttttgcact tcataagaaa ctaaaacttt ttctaaattc tttcttatta taatgaagtt
    13441 ttgttccatt atcttcttac ttgccttttc tataataaat tccatatgta cagaaggtaa
    13501 taaaatttcc ccagttccat gttctgtata tttacttaaa gcatcaatta tatctaagtt
    13561 tccttttatc ttattttgta atttcatgca actatcttgt aagaataatc cactttgttt
    13621 ggctaatacg ttgataaaac tctctatagt aagacttgtt gtactttcca accagttttt
    13681 aaatactttt acaacctcat catattttgc tatttcttga atcattgtta tacttccaat
    13741 aatattgata aaatcttctg tatacgcctt aacataatct tctaggctag atacgatatt
    13801 gttttgaatt tcttttatca acgtatctaa aactaatctt gcatctgcac taattggata
    13861 ttggaatgct gatgtcttat ctttaacttc atctaattct agtacttgct ttaataagcc
    13921 ttccctctca tctgatgcaa gtggcttaca aagatgaata ttttttccat tatcttttag
    13981 caattcttca aataaccaag ctttttcctc tatattactg tctaaatttt cgcataattg
    14041 ttcatatttt ctttttataa cattatatat ttgtttttct gttcttccta agaaactttt
    14101 tgaaatgaaa aaagttatac tacccttaaa attttcttta tgaagacaca tatttaactg
    14161 ttggaacagg tctagtactt ttgtaagtct agaatctaat atatctgctt ctggtatcaa
    14221 tacaattact gcacatatag atgcagaatt tttaaatact tcacctaatg aaactgctgc
    14281 actaatatca tgggctactc ccctattgtc gctaaaacct gcagtatcac ataattttgc
    14341 atccattcct tctattggtt ttctcatatt tacaatgttc gggtataaag tttgagaaac
    14401 agctcctgaa ccaatctctg ccacagggtc taagcaatca atatatgata taccagtatc
    14461 ttcatcttct acttccatca ttacacatcc tgcaagatag ttaattgcag tacttttgcc
    14521 acatcctgtc ccaccaagaa ttagaattaa attttgattt tcagccttat ttattgctac
    14581 ttttccttca tttaataaaa gtgttatttc ttctaaaagt tgattgttat tttctggcat
    14641 ttattttccc ccttggttat atattttatt taaataaagt ttaatccctt aagtagattg
    14701 caaagttttt agactatatt taaatttgtt ttttattttt tatttttaat aaatttgcat
    14761 tttcactaaa taattattct tctttgttta ttaaaataac tgtgttgtat aatataatct
    14821 ttatcaacac agttatttta tttaatgcgc ttattttatt gtattttatg taatacagtt
    14881 gttttttata ttatatgtcc attatttttc tatggttatt acatatagat ttttaattat
    14941 atttgtacca ttaatttaaa cattcctata ctactgctta agttttacac ctataccagc
    15001 ttgaatattt tatttttatt tgcttaaata gttcaactat actggtttaa ataggttatc
    15061 tttatttgct taaatagttc aactatactg gttaaatagg ttatctttat ttgcttaaat
    15121 agttcaacta tactgattta aataggttat ctttatttgc ttaaataagt tcaactatac
    15181 tgatttaaat aggtttcctt tagtttaaat aattcaccta tactggttta aataggtttc
    15241 ctttagttta aataattcac ctatacctac ttgaatagtt cacttttatt tgcttaaatt
    15301 ctataccaat actggcttaa acattatact accatgattg tattgtctat cttcaactac
    15361 aataaaaaca ggttctaaat ctttagtaga tgttattttt aattctaaaa aaatattatc
    15421 agttggtaat atttttacat cataattatt taaattatta ttcgtgatac tattaaatac
    15481 atcaccttga cgttcaaaaa aaacattatc aactattaca aaataaacat cttcttttct
    15541 actattttca acctctatag tattttgttt agttatattt agtctcatct tccacctcct
    15601 attaatatta cttaattata ttaatacttg taattgttgc attatgttca tcacaaggaa
    15661 gaggtttaaa aacaactatc tctgctaaat aattctgtgg aggatttgta actgaagtag
    15721 cattgcaaat aaatttaaaa tttgttcctg ctacaacttg agtagaaaca ataagtggtt
    15781 cataaccaac cccttctaac attcctacag cttcattaaa tacttttaaa tcttcttctt
    15841 cgacagctct gaattttgac catccaccaa caaaaagact catataaaaa cctcctttat
    15901 atatatattt atttatatat agtagtacca attttctcaa tattcaatat tttctgtgta
    15961 actggtcaat gaaaatgcat aactggataa aaatacttat aaaataactt aactttacat
    16021 ataaatagct tactttacat gtaataagat tattctacaa tatgaaatgc atcttgtttt
    16081 gaatatattc taaatacaat aatggatatt ttcaattatt ataattagaa aatatccatt
    16141 acttaacttg ttttatttaa aatcacatag agactttatt atttttttta ttgcatgaat
    16201 agctatttca ggtatcataa ggtgatatac cccctccttg aaaccacaaa aaacatgaca
    16261 aactttacga atcttgtctt aaaaaactac aggtacattc cttatttgtg gattggagta
    16321 gccataacaa gcaaatttta caatttttat gatgacaaaa atcaataaaa tcgcttagta
    16381 tataacacga aatactactt gttactatta agaatagtta gataggaagt atgcattata
    16441 caaataaagg aatcaataaa gaaagttaaa acatccctac aaattaaaaa tctgttacat
    16501 ttttctatat ttaaacgtta tttacttaca attggagaaa taacaggttt tccttctcgg
    16561 tcaagtaaag gcgtaaatcc ggctgcattg ccataatagt ggaatacata gttcacacct
    16621 gtttctttat ccacccaaat ctccgttgca tttattttcc cttgtgaata tactttttca
    16681 aatctatctt ttcccatttt ataatcctcc atatttttga ttggtctatg ccttcttcac
    16741 ttaagtagaa aaaatacata acttattttt ttaattctaa tatgagcacg taaaaatgtc
    16801 aaacagctta tttaatttca taacttcatg ttactgttcg taaccttgtc tgtttactta
    16861 cactgcatta cagcaccatt ttatccttta cattattgta ttgcacacag taaaaatgct
    16921 tactttatgg gatttttcaa ctaaaaaaag gattttatct ccacaaaaca tttactattt
    16981 gttacaatat acctaatttt aatctcatat caacatttaa tgaagatata acctttttca
    17041 aatattgtaa agactcctta aaaatattag aaaaagattc tgcaaatctc tcaacatctc
    17101 ctttttttaa atacctaagt atctcaaaac atacatcaaa acgtgttttc aaaatttcat
    17161 tatattcttc atgaaaaaat ctctctaaat agattccaaa tatcatatat tgttttaaat
    17221 gcaaaaatgt ttcctgtaat acataaattt gtgtataatc tactatctta caaagtaaaa
    17281 caaaatctgg ataaacctta cactcttcac aattattttg taagtacctt aaatgagttt
    17341 ctattttatc tacagctatc aaatccattt tatttcctag taaaagtact acatcctcaa
    17401 gagtaatcgt aacaaactcc atagcatcca aaagcaaact caacctttta gctccttctt
    17461 ctgtatttat ataatcatca tcatattcag aaaaaagcgt tacatatgtt cccttgccat
    17521 taattgtttt agcaattccc aattcattta gctcattata ggcacttcta actgttggaa
    17581 gtgatacatt atatctatta attatcgaag taattgatgg tagacaatct cctattttaa
    17641 tattgccttc aaaaatttga caaattacat ctgaaacaat taagtcatat aaataacatt
    17701 tttccaacgt tacagaatta aaactacttg tatctatact ttgtggagca cgattttcta
    17761 ccattttaag tatggattct ctacaagctt tatacatata tgttaatagt tttttaaatt
    17821 caattagatt cccatccaat ccatataagt aagtttttct tacctgctct atgtatttat
    17881 tacgaaaaaa gtctatacaa caattatcca agttatccaa gttatcgaaa ttataggcca
    17941 attgtgaaat aatgacatca tgctgaataa tctcacaaaa atggtgaatc aggaaattat
    18001 ttgttttact tattagttta tttatatatt ttagcctttg ttctttaaag actaaataat
    18061 tagaactatt tttttccata caatcgataa tctcgtttaa ttcttcaaag tctttagatg
    18121 taaatctttt aatattgtac atagcaatag aaggaaatat taaactaaaa atcttatata
    18181 tttctgatat ttgtaaaatc ttctcatata ataagtcaga ttctattgat tgtttactcg
    18241 tactctggat taaaactggt ctagaaccag cttttgtctc tataaagccc ttttctgaga
    18301 gcatttttat tacagttttt atagtatttt ttgataccat atattcttct gacatgcttt
    18361 ttatagaatc aagcctatct ccaatagtaa ttttaccagt ataaatttgt tgaattatat
    18421 gctcaaaaat aattaaatat tgtggttttc tcttcatatt tttcctcttc gataaattag
    18481 atttattgtt ttttgtaagg tatatttact tttatttaat agggcaaaat agttgcttat
    18541 tttttcctca taatctataa ttaatataaa ccatttatat atatggtcta agttttataa
    18601 tactgtaatg cagtaaaata gcatgttgta gctatactac agcaaattaa cataccattg
    18661 tagtatatta attggaataa ttttaagtac ttcaaaattc cagcaaaaca tatatgtgtt
    18721 tttgatatta tgtatattcg ttaatagaat agctatactt gttttacata ataaattata
    18781 tgatacttgc tatatgtaat cactatattt aatacacata actattatac ttgctatatg
    18841 taattactat actttataca catagttatc atatatgcta tatgtaatta ctatacttta
    18901 tacacatagt tatcatatat actatatata attactatac ttggacacat agttatcata
    18961 catgctatat gtaattacta cacttggaca cataactact atatttacta tatgtaatta
    19021 tactatactt ggacatatag ttatcataca tactatatgt aattactata cttgaacaca
    19081 taactattat atttgctata tgtaattata ctatacttgg acatatagtt atcatacata
    19141 ctatatgtaa ttactatact tatacacata attatcatac atgctatatg taattactat
    19201 acttatacac ataactatca tacatgctat atgtaattac tatacttata cacataacta
    19261 ttatactttc catacataat tactatattt ggacacatag ttatcataca tactgtatat
    19321 taagatataa tactttttaa attttatata acacagacac atgcaataaa aaagaaggta
    19381 tccataataa gctctttgca tgtacctaaa taaaaactgt aaaatagaat atataaaatc
    19441 taatctattt taagtaaata caatttcact ttaaaagagg atgtactatg aaataccata
    19501 tatttttaat cataactact atattaataa tcgaactatg taacatttac atatgcaaaa
    19561 tagcatcttt tggaaacaaa aatataacta tacataagaa ttacaaatat atttttttaa
    19621 taaaaccatt aaccttcttg ataataatat tcacaaaatt accattacca ctatattata
    19681 tattgtttta catagtaagt cataaattgc tcttaagcag aaaaagttct actaacaacc
    19741 attttattcc caatatggca gtaataagtt tttgtatttt acaccttatt actgtaagta
    19801 caatatcact tgttaaaaat acaagtccag atataatatt tgcaaatatg acctataagt
    19861 taattagtat tttaatagct tctattttag attttatctt atggtactct atgaataaaa
    19921 taaaagagca tatttatata ataactcaaa atcaaataga gttcagtcta tttttaaaat
    19981 ttatctggtt cactttagga tatatattat ttgatagtat acaaattaca tttgctccac
    20041 caagttctct aacttcctac tttatattgg gaagtaacat attattaatc ttacaactaa
    20101 ttatattcat caatcatata tattccattg aaaaaaatat ttatttagaa aaagaacata
    20161 atagactaaa aatgataaaa caagaacaat tactaaaagt aaatttatta aagaaaaaag
    20221 ctaacattga tgaattaaca tcagcatata atcgaaaatt tgcttttgaa aaaatacagc
    20281 attacattga taacaattta ttattttcat tgatatatat cgatttggat aaattaaaga
    20341 cgataaatga tacatatgga catttagctg gggataacta tattattaac ttctcaagta
    20401 tagttattga aaacttagga atagatgaca tatttgctag aataggagga gatgagttta
    20461 tagttattat gcctaaatct aatgaaaaca ccacaaaaga atttatagag aaaataagta
    20521 aaattatgga taatacgata tcttttagct atggtattgt agaagtttct agcgaaaaca
    20581 aaatgactgt agaagaaatt attaatattg ctgatattag aatgtacact aataaacaaa
    20641 ataatcataa aaggaacaat aactaaaatg aatatttaca tgagcttact tgtagtctca
    20701 ctatgttttt tatcttatta tctctatcat tataattttt ttaaatatct ggacataatg
    20761 attaataact ctaaaaataa atacacagta t
//
LOCUS       DAEHWO010000075        20646 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEHWO010000075 DAEHWO010000000
VERSION     DAEHWO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20646
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.075"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            365..1258
                     /locus_tag="KNP54_003051"
     CDS             365..1258
                     /locus_tag="KNP54_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBF0893916.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1258..2652
                     /gene="gltA"
                     /locus_tag="KNP54_003052"
     CDS             1258..2652
                     /gene="gltA"
                     /locus_tag="KNP54_003052"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBF0893917.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3018..5237
                     /locus_tag="KNP54_003053"
     CDS             3018..5237
                     /locus_tag="KNP54_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0893918.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5384..6130
                     /locus_tag="KNP54_003054"
     CDS             5384..6130
                     /locus_tag="KNP54_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893919.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6130..8010
                     /locus_tag="KNP54_003055"
     CDS             6130..8010
                     /locus_tag="KNP54_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0893920.1"
                     /translation="MDFRKFAYNNIVKNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGVII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAQITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8129..9520
                     /locus_tag="KNP54_003056"
     CDS             8129..9520
                     /locus_tag="KNP54_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0893921.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9627..10667
                     /locus_tag="KNP54_003057"
     CDS             9627..10667
                     /locus_tag="KNP54_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBF0893922.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11156..11809
                     /locus_tag="KNP54_003058"
     CDS             11156..11809
                     /locus_tag="KNP54_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBF0893923.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKAAEKIDGIIDGMKF"
     gene            11885..12094
                     /locus_tag="KNP54_003059"
     CDS             11885..12094
                     /locus_tag="KNP54_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893924.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12234..12800)
                     /locus_tag="KNP54_003060"
     CDS             complement(12234..12800)
                     /locus_tag="KNP54_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBF0893925.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            12961..13614
                     /locus_tag="KNP54_003061"
     CDS             12961..13614
                     /locus_tag="KNP54_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBF0893926.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGFSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13772..13948)
                     /locus_tag="KNP54_003062"
     CDS             complement(13772..13948)
                     /locus_tag="KNP54_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893927.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
     gene            14476..15420
                     /locus_tag="KNP54_003063"
     CDS             14476..15420
                     /locus_tag="KNP54_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBF0893928.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            15442..16068
                     /locus_tag="KNP54_003064"
     CDS             15442..16068
                     /locus_tag="KNP54_003064"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBF0893929.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            16102..17151
                     /gene="hisC"
                     /locus_tag="KNP54_003065"
     CDS             16102..17151
                     /gene="hisC"
                     /locus_tag="KNP54_003065"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBF0893930.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            17154..17732
                     /gene="hisB"
                     /locus_tag="KNP54_003066"
     CDS             17154..17732
                     /gene="hisB"
                     /locus_tag="KNP54_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBF0893931.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            17734..18339
                     /gene="hisH"
                     /locus_tag="KNP54_003067"
     CDS             17734..18339
                     /gene="hisH"
                     /locus_tag="KNP54_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBF0893932.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            18336..19058
                     /gene="hisA"
                     /locus_tag="KNP54_003068"
     CDS             18336..19058
                     /gene="hisA"
                     /locus_tag="KNP54_003068"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBF0893933.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            19040..19798
                     /gene="hisF"
                     /locus_tag="KNP54_003069"
     CDS             19040..19798
                     /gene="hisF"
                     /locus_tag="KNP54_003069"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBF0893934.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            19826..20494
                     /locus_tag="KNP54_003070"
     CDS             19826..20494
                     /locus_tag="KNP54_003070"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBF0893935.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDVIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         8198 a         1941 c         3642 g         6865 t
ORIGIN      
        1 ttattatgaa aacctaagtt aatttattaa ataaataatt gaataaaaaa attttattat
       61 gtatttataa aatttttgtt acaaatttgg cataatatag tatactttaa gtgtgtatta
      121 ggttaaatct ataacaaatt agacgtatga tatagactta gtgtttattg gcatttacaa
      181 gaaatttgtt aatatcaact atttgtagtt tgggcagtta taattattat aggggggatg
      241 tccaatacaa aacaatcaac caagaactaa tattatatta taaagagtta tagttttgtg
      301 tgtttatgtt tttaattaaa tttaaagtgg gaaaaatata tttgttagaa tggagaatag
      361 cgagatgagt aataaaatag ttagtaagag acaattaaca gatagtattt atttaatgga
      421 aatagaggca cctagagttg caaaatcttc tcaaccaggt caatttataa taattaaaaa
      481 tgatgaaaaa ggagagagga ttcctcttac aatagctgac tatgatagag aaaaaggaac
      541 agtaactatt gtattccaaa cagttggtgc ttcaactaaa aagttagcaa tgtttgaaga
      601 aaacgatttt gtaatggatt ttgtagggcc attaggacaa gcaagtgaat ttatacatga
      661 agatatagaa gaattaagaa ataaaaagat attatttgta gctggtggag ttggttctgc
      721 tccagtttat ccacaagtta aatggtttaa agagcatgga ttagatgtag atgtaataat
      781 tggtgcaaga actaaagaat taattatatt agaagatgat atgaaaaaag tagctaaaaa
      841 tgtatatgta tcaacagatg atggtacata tggatttaat ggaagagtta cagacctatt
      901 aaaagattta gttgataatc aaggtaaaaa atacgaccaa gcaatagtaa ttggaccaat
      961 gataatgatg aaatttatgt gccaattaac taaagaacta aatataccta ctatagtaag
     1021 tttaaataca ataatgatag atggaacagg tatgtgtggt ggttgtagag ttagtgttgg
     1081 aaatgaaact aagtttgcat gtgtagatgg tcctgaattt gatggtcatt tagttgattt
     1141 tgatcaagca atgagaagac agtctatgta caagactcaa gagggaagag ctatgctaaa
     1201 acttgaagaa ggcgatagtc atcatcatag taattgtgga tgtggaggta acaaataatg
     1261 gatgctaaaa aagtaaaagt accagttaga gaacaagaac ctgctgtgag agcaacaaat
     1321 tttgatgaag tatgcttagg gtataataaa gaagaagcta tggcagaagc taatagatgt
     1381 ttagcttgta aaaaaccaaa atgtgtgggt ggatgtccag taggaatcga cataccaggg
     1441 tttataacaa aaattaaaga agatgatata gaaggtgctg ctaaagtaat agctaagagc
     1501 agttcattac cagctgtttg tggtagagta tgcccacaag aaagtcaatg tgaaggtgta
     1561 tgtatacttg gaataaaatc agatgctgta tcaataggta aattagaaag atttgtagca
     1621 gattggtcaa aagaaaatga cataaattta tctgatacag agcctaagaa aaatcaaaaa
     1681 gtagcagtaa taggaagtgg tccagcgggt ctagcttgtg ctggtgattt agctaaaaaa
     1741 ggctatgatg taacaatctt tgaagcaatg catgagccag gtggagtttt aacttacgga
     1801 atacctgagt ttagacttcc aaaacaagct gttgttcaac ctgaaataga caatataaga
     1861 aaattaggtg taaaaataga aactaatgta attgttggta aaacaattac agtagatgaa
     1921 cttatagaag atgaaggatt tgaagctata ttcataggtt caggagctgg tcttccaatg
     1981 tttatgaata taccagggga aaatgcaaat ggagtatttt ctgcaaatga gtttttaact
     2041 agagtaaact taatgaaggc ttatagagat gattatgata cacctattag ttctggtaaa
     2101 aaagttgctg tagtaggtgg tggaaatgtt gctatggacg ctgctagaac tgcattaaga
     2161 ttaggttcag aatcatatat agtttataga agaagtgaaa aagagcttcc agcaagagct
     2221 gaagaagttc atcatgcaaa agaagaaggc attatattta atacattaac aaatcctaag
     2281 gaaattttag tagatgaaaa tggatatgtt aaaggtatgg tttgtataag aatggaatta
     2341 ggagagccag atgattctgg aagaagaaga cctatagaaa tagaaggttc tgaatttgta
     2401 cttgatgtag acacagttat aatgtcactt ggaacaagcc caaatccact aatatcttct
     2461 acaacaaaga gtcttgatat aaataagaag agatgcttaa taacagatga aaatggtcag
     2521 acttctaaag agggtgtatt tgcaggtgga gatgctgtta ctggagcagc aacagtaata
     2581 tctgcaatgg gtgctggtaa aacagcagca gcatcaatag atgaatattt aaaagcaaaa
     2641 gttaatgctt aatttgtaaa ttaaagagag ggtgtctcaa aatgaacttt ttagttcatg
     2701 aggcactctt tttgtacaaa atcaaatatg ttttaatcat ttcaacaatg aaaatttcat
     2761 tcctgtagaa agtctaactt ttaggtctta gtacaatctc tattttgatg tagccacttt
     2821 tttagatggt ttaataattt atcagttatt attgtaatat ttgatactaa gtaacataac
     2881 tttgtctaac tatgataaaa tagttataca ataaaggtct tgtaaggagt gaataatgtg
     2941 tggctaataa aatcagattt gtcaaatcta acattaaata atagaaaaat aaattgtgta
     3001 attaatggta ttttaatatg aaaaaaagag aaaaagtatt tgatgggcta gtttttaagc
     3061 atatattaat cttattaata ctattagttt tgattgattt aacaagtacc atcatatatg
     3121 caagtaactc tatggaaatt acttctagaa atatgattga ggcatcaaaa agagaacttg
     3181 aaaactattt agaagtaaac atatctttat taaaagctct tagtcaagat gatagatttt
     3241 ctaatggtga aacatcacta attgaaaagg gaaaattatt aagtccatat caaaaggaat
     3301 ataatctttt tatgattggt ataacagata caaaaggaaa tgcttcaagt acatataggg
     3361 aaaatgttaa ctcaataaaa gataagccta gttttgagaa agcaattaaa acaaagcaag
     3421 tagtagtttc agatattgaa gtcagtaatg taacaggtga caaagtattt atcatatatg
     3481 taccaattgt aaaaaataat gagatgattg ggaccatttt tgcttctttt tattttcaag
     3541 atgtaaataa tttaataagt agaagcaatt ttgatgattc tattaaattt ctaatgatag
     3601 ataaagatta tactattatt tctcatccaa acaaaaaata tgtaaatgat aaaagtaaga
     3661 tgcttgattt agaagggaat attataggaa ccactaaaag tgaaatctta aaaaatataa
     3721 ataaaaaatg tcaaggtgat tttttatctt gggataattg gagattatat aatgtaaaat
     3781 atacgaacat aaagtggact aattggactt tagtatcaaa atgtaatata tttaagaact
     3841 ttaaaaatct aatagttaat tttatgataa agttgtattt ttatatagta atatttatga
     3901 tattgtggaa attaagtaat gctaaattaa tagaacaact taaaaaattg gcttattatg
     3961 attctttaag tggaataaaa aataaagaaa agtttagaaa agattctatg tatattttaa
     4021 agaattatta tcaagataat ttttacttag tacaattgga tgtcaataaa tttaaatata
     4081 taaatgagat gtttggatat gctgaaggga ataagatatt aattcatata tcacaggttt
     4141 taaataataa tacaaataaa tatgaaattt gtgctaggat ggataatgac cattttatat
     4201 tgttgattgc ttgtaacact gaagatgaac ttttaaatag attatctaaa ataaataaag
     4261 aaatttgtaa cttaaatact actaactcat ctaagtataa aattgttatg tcaagtggaa
     4321 tatataagat tactaaaaag gatgatatta aaaagattga cttgttaatt gatagagcaa
     4381 atattgcagc aaaaagtaaa aaggaaaaat atgaacattc atattcattt tttaatgaag
     4441 atacaagaaa tcgattgtac aaggaaaaac gattggaaga taatatgaat aaagctttag
     4501 aaaaaggtga atttatagta tattatcaac ctaagtatag tttagatgat gtaaatgaaa
     4561 ttgaaggagc agaagccttg ataagatgga atagtccaga atttgggttt atttcaccta
     4621 tagattttgt acctttattt gaaaagaatg gttttattgt aaatattgat atgttcgtgt
     4681 ttgaagaagt atgcaaaaca ttaaacaagt ggataaataa agggtatact cctgtaccaa
     4741 tctctgtaaa tatgtctaga gttcatttat atagggataa ttttatagaa aatataactg
     4801 atttgataag taaatacaat atatctcctg agtttattga acttgaacta acagaaagtg
     4861 ttgtgtttga taatttaaat atattgattg atataatgaa aaagattaaa gagataggat
     4921 tccttatatc aatggatgat tttggttcgg gatattcatc tttaaatctg ttaaaagacc
     4981 tttcttttga tattttaaaa ttagatagag gatttttaat cgaaacaaca gatacaaaac
     5041 gtggaaaaat tattatttct aagattgtgg aaatggcaaa agcgattgat attaaagtaa
     5101 tctgtgaggg cgtagaaact tatgaacaag tagagttctt gaaagagata ggttgtgata
     5161 aggttcaagg atacttattt gctaaaccta tggtattaga tgaatttgaa aaacacttaa
     5221 actttaaatt tgattaatca ttaataatta ttagactata atatacccta acaacttact
     5281 tacaaatatg taagttaatt gttagggtat ttttatggtt aaagtagtat attcacgata
     5341 ttatggtatt gtagtaaaaa taaaaaatta tggagaatat aaaatgaaca tattgagtat
     5401 tagaaatata tcaaaaacat attgcggaaa tattccattt aaagcattag ataaggttag
     5461 tctaaatata gaaaagggag aatttgtgtc tgttatggga ccatctggaa gtggtaaatc
     5521 tactctttta aatataatat ctacagttga tagacagagt gaaggtgagg ttgtattaga
     5581 tggatatgat gtaagtaaat tgaaaggaga aaaacttgct gaatttagaa ggaaacaact
     5641 tggttttgta tttcaggatt ttaatttgat tgacacttta actgttggcg aaaatattat
     5701 gttgccactt acactagagg gggcaagtat caaagatatg aatatacaaa ctaaaagtat
     5761 atctaaattt ttaggaatag ataaaatttt agatagaaaa acctatgaaa tttcaggagg
     5821 tcaagctcaa aggtgtgcta ttgctagagc tattataaat aaacctgcca tacttcttgc
     5881 agatgagcca actggaaatc ttgattcaaa atctactgat gatgttttga aattatttac
     5941 taggataaac aaagaacaaa aggtaacaac acttatggta actcatgaag catatagtgc
     6001 aagttattca gatagagtaa tttttataaa agatggttgt atatatacag aaataaaaaa
     6061 atctgaaagc agtaattctt tctattctga tatactagct gttttgtctc aaataggagg
     6121 tgtaagatag tggattttag aaagtttgct tataataata tagttaaaaa tttcagggca
     6181 tatttagcat attttttaag ttctgttttt tctataatga tattttttgt ttttgcagtg
     6241 tctatgttcc atccaattat aacaaaatct ggaatgcaga gtggttctac tgcatttatg
     6301 gctcttatga cttcagaatt aataatattc ggttttagtc tactttttat attgtactct
     6361 ttaggaaatt tcttgaaata tagattgaaa gattttggag tattgatgat aattggaatg
     6421 agtaacagac aactgaaaaa attgatatta attgaaaatt tgataatagg atttttagca
     6481 gtgatgttag gaatattact tggtttatca atttcaaaat tgtttttatt gtatttaagc
     6541 aaactgtttt atatgaattt aactgaattt tattttccag taaaagcaat gctattgact
     6601 attgtatcat ttatgatttt atttttgata acaggaccaa tgagcttaaa attattgagt
     6661 aaaaagagca ttttagagct tttagtaggt acaaaaaagc ctaaaaaaga gataaaatct
     6721 tcaaagctat ttggaataat tggtgtaata tgtcttatat taggatatgc tatgatacta
     6781 tttggcaata agttaaaaat aaatggaggt atgtatacaa cagcactatt aattactttg
     6841 gggatatttt tatttttttc tcaatttact attttgatat taaagtattt aaaaaataaa
     6901 gaaaaatttt ataagaacaa agtaaatatg ttacttataa gtaatttgat atataaatta
     6961 aaggataata cacgattgtt atttttaata acaatacttt tatcggctac tttagtagca
     7021 tttacaacaa cttcaacact tgtaagttct caaggagaag cttctaaaaa taattttcca
     7081 atggtttact catatttttc agagcataat aatgaaaaag aatatgaaga actacaacaa
     7141 attagagaag caatcaaagg atatgattat aaggagttaa gttttcctgt acttaaatat
     7201 aatagggaag tcttactaag tgtaaagaat tataacaaat tatcaaagga attgggatta
     7261 gataaaatta gttcaaagtt agaaaaatat gaaggggtta taattcctag tagcaattca
     7321 caagaacata taaattcttt aaaacaatta aaaaattata gtataaaaaa tttaaatata
     7381 gaagtaaaaa aatcaaaaaa taaaataatt tttcctacag gactgtttag taaagttgta
     7441 gttataagtg atgacttata caatgaagta aaaggtgaat tttcaaaaat taattttcat
     7501 ggatttgatt ataaaaactg gcaaagcagt gcacagataa ctgaaaattt aaaagaaaaa
     7561 cattttaatt tggatagaga atataacagg tcatattttt taacattacc agatatgtat
     7621 ttagtagagt tacaacaaag taaaattctt caatttatgg gtgtttttat aggagtgata
     7681 ttatttatag cagtttttag ttttttatac tttagattat atacagacga gatagaagat
     7741 aatgtaaagt acaaaaaact atcaaaaata ggtctatctt ttaaaaatat gaataagatt
     7801 gttagtatag agataggtac attgtttttt ataccgtatt ttatagcaat tataaatagc
     7861 ataatttctt tactgttttt aaatcaagta ttaaataata gttttaagtt agaaaatttg
     7921 ggtatattac tactgatatc atctatatat tcactttatt tttacttatt aaaaaaaatt
     7981 tatactagaa aagtttggtt ttttgattaa agtggtatat aatagatata taaattaata
     8041 tttaaaaagt agttaatatt aggggagggc atttgcacct cccttgtaat atgtggaaaa
     8101 ttgaatatta gaagaaggag gagacttgat ggaaaatcaa caattattag gaacagaacg
     8161 aattagtaaa ttactactaa aatattctat accagctata ataggtatgt tggtaaatag
     8221 tttatataat gtagtagata gaatttttat tggaaatata ccaggggttg gaccacttgc
     8281 aataacaggt cttggtgtaa caatgccaat aatgacaata atacttgcat ttgggatgtt
     8341 gataggtata ggaactacta ctaccatatc aataaaactt gggcaaggta aagtagaaga
     8401 ggcaagaaaa cttataggaa atgcaatgac gttatctgta ataacaggaa ttatcataat
     8461 gatacttgga atattatttg caaataaaat acttacattg tttggagcaa gtgaaaatac
     8521 tttaatatat gcaaaatcat atatcaatat tatattatta ggtacagtag taaatcttct
     8581 ttccttttct ttaaaccact caataagagc tgatggtagt cctaaaattt cagcaggaat
     8641 aatgatagta ggatgtttaa ctaatatagt tttagactgg atattaatat ttggattcaa
     8701 tttgggaata caaggagctg caattgctac agtaacttct caggctctta cagctatttt
     8761 aactataggg tattatataa gtggaaaatc aaacttacga ttcagtaaat ctaatctaaa
     8821 attagataaa aagctaataa aagcagtgtt tgcaataggt atgtcgccat ttgctatgca
     8881 acttgcagca agtttagttc aagtaatatc aaatattgca cttaaaactc atggtggaga
     8941 tttagctata ggggctatgg ctactatttc ttctattgca atggtatttt tgatgcctat
     9001 ctttggaata aatcaaggag cgcaacctat tataggtttc aattatggag ctgaaaaata
     9061 tgatagggtt aaaaaagcat atttaggttc attagtagta gctactataa ttttatgtat
     9121 gggtatggta gtagttatgc ttttcccaga agctattata ggtatattta ataaagaccc
     9181 tgaacttatg aatatatctg ttaatggatt aagaatatac ttacttatgt tgccaattgt
     9241 aggcttatca gttacaggaa caaactttat acaatctata ggaaaagcaa aaatggctat
     9301 gttattgagc cttttaagac aagtaatttt attgatacca gcagtattaa ttcttcctac
     9361 attcttaggt ttacagggtg tatggacagc tcaaccagtg tctgatttta tagctacagt
     9421 aattacaggt atagttgtat ttagagaatt aaaaagatat actcctaaaa ctgaaaaatt
     9481 aaatgaaaat gaaagactaa acgagataac tactgagtaa aaatataaat tcagataatt
     9541 gagcaagaaa ttgcaaaaaa tacgattata tgataaaata aaaccgctgt caaggataag
     9601 agaaattcta attatggagt gattttatgg aatttacaaa gaaaagcaaa ttaaaaaata
     9661 tgtatgtaaa catgaatgta gctagaatgt tgtctaagat aaatgagtat aagggtagac
     9721 aactgcttta caaaaaacaa ccaaaagaaa ttttagaaaa cttagaaaaa aaatctttag
     9781 tagattgttc tgaatctaca tacattggaa atcaaagaga tagtagtaat tttaatctag
     9841 aaaagttgat aagtaatgaa gttacaccta gaagtagaga ggaattgagt attgttgaat
     9901 acagagatgt ggtaaaaact attaacagtg cttatgagag tattcccatc agttcacaaa
     9961 cgattcttga gcttcatgga tacttatata aattttcatc tactagagga ggaagttata
    10021 agtcagataa tgattttatt gaacacaatt taaaacctag cgaatttata agtattgatt
    10081 caagtgtcaa taaagttgaa aaagctgtag aagaaatatg tgaagcttat aatacattga
    10141 tagaggaaga tgaaattgat atattaatat taatttctgc atttgtgtta gatttcatat
    10201 tgatacatcc attcaaagaa ggtaatataa aaatggcgag agtacttatc ctattgttac
    10261 taaataaaaa tgggtatgaa gttggaagat atataagttt aggaaagata tttgatgata
    10321 gttcatatga atattatagt aatttaaatt atttgaaagc ctcaataggt agtgaaaaag
    10381 cagatatgaa tgcatggatt gagtattttt tagagacgat attaactgca tatgagaagc
    10441 tggatgatag tttaaatata tctgataaga aaagacaaac aaaaactagt agaatagaga
    10501 aaataataaa ttctaccctt ggatatttta caaaagaaga tataagagat ttatgtcctg
    10561 acattccaga acctactata aatagagttt ttaataatct aagaaaacaa gataagatag
    10621 aagttgttgc aagaggaaga agtgcaaaat ggaagaaaaa atattaaaaa atgtttagat
    10681 aactaaaatg gtatagtgtt ttacactata ccatttttaa tgtcattagc atgagcaata
    10741 atttaacaac ttaagcaata tcaattttat ttattgatta tttttgaact gaaaaatggc
    10801 gttatatggt atacctcagt ggtaattaat tttggatgag aagatataat attacagaat
    10861 atattaggag tatatgtaga aaaaatataa taaaagtgtg aggcttagta attaacaaat
    10921 tatgtggctt cacacttttt tataaaataa agatacttag cagaagaata ttttagttga
    10981 tatgtttata agatggtact tgtttgggta aaagtataaa tagtaaaaaa gtagaagtaa
    11041 tgtgtataaa aacgtaagtt acattctgta ataatagtta ttttataatt caacaaaaga
    11101 atagaatggg tatatttgtg aaataataat ataaaataat cttaggagtg agcttatgaa
    11161 gaaaaaatta ttatatataa atgtaaattc aaaacctgaa gacttatctt caagtaaaac
    11221 tgtagcaaga aaatttataa ataaatttat ggaaaaaaat aaagattttg aggttgaaga
    11281 gatagacctt tataaagaac atataccaag acttgagtat cagtactttg aaaaaagaaa
    11341 tagcatagtt agtgaagaaa atgctaaaaa tttagacgat aaggatagaa aagaacttac
    11401 aaagattaga aatctttgtg accaatttgt gagtgcaagt gtatatgtaa tagcagcacc
    11461 tatgtggagt ttatcttttc cagcaccact taaagagtat atagattgta taattcaaga
    11521 tggaaaaact atatcttttg aaggcaatga taaaccacaa ggaattttaa atgatattga
    11581 tagaagtatg gtatatatac aatcttctgg tggacacata ccatgggtgt tgaagccagt
    11641 tatgaataaa gggttaaatt atgtggaaag tattatgaaa tttataggaa ttaaaaaatt
    11701 tgatgaattg ttagtagatg gaactggaac tagtgaagaa gaaagacaag ctgctataga
    11761 aaaagcagct gaaaaaatag atggtataat agatgggatg aaattttaat tataatattt
    11821 tattaaaaat ataaaggaaa aacctctttt aatgtagaaa cttatattga aggaggcgag
    11881 aatcatgcga gaagaaaaaa gtaatgaaaa gtatgattgt tattggtgta atcaagagaa
    11941 taatttctgt gtagaaataa aagataatat agtcatgata gatgatggca ctggtacgtt
    12001 aaaacaagcc gttttcatag ggtataaaca aatccaaatt aatttaaact gttcacattg
    12061 tcaaaacttg aatagaataa aattaaattt gtagaatttt aaaatggaaa ttattgaagg
    12121 aattaaaaat agaaagtgtt aatatttaga ctgaaaatta tattttatac aataaaagtt
    12181 tatttaaata acattgtatt ttaatattta ttttcagtct tactttatta aaattatttt
    12241 ttggttatgt ctggaaaata tctgtctact aatttttctg aaatattttt taattggtca
    12301 gccattgaag tcagacttaa taaggctatc aataaatcat ctttattttc tggatttata
    12361 ctaatatttt caaaattaga ctctataaag tccggtatat tctttctttg attttctttt
    12421 attaacatga atttttcgta acatgaaact aaatcttttt cactgaaatt atccttttca
    12481 tacacaccat gtaagattct tttaatttct tgtattgtaa gtgtattttt catagaataa
    12541 ataattatca tctgtaaaat ttgttcttta gtatactttt ttcccttaac tggtttgatt
    12601 aatccctctt tgctgtaatt atttatcatg gttttagtaa gaattttatc actttcaaat
    12661 cttttattgg cagaaagctt attgtcaatt agagaaataa tttgatccat atataagtca
    12721 atagatggaa tatcgtttga agttatatct gcattattta gtgtttctag tattatagta
    12781 ttaagttcat tattcatcat atgttacctc cataatatat ataatacact aaattagaaa
    12841 gtaaaacaat attaaggctt gtaaaaaaaa cataaagtgg tataattaaa tatataatat
    12901 agtaatggaa actatatttg tgaatctgat ttttaaaata cataattgta ggaggacgaa
    12961 atgtatcaat tttttttaaa gggtagagac ccaataagca gtttaactca ttttataggt
    13021 gcttgtttat ctcttttagc aactataatt ttagtttttc aatctgttac attacaggaa
    13081 acttctctct tgatgatagt atctgtatcg gtatttggat tttcactaat tgctttatat
    13141 agcgcaagtt cgtattatca ttttttaaag gggacaccag aacaagaatt gttttttaga
    13201 aaagtagacc atgcaatgat ttacgtattg attgctggct cttatacacc aatatgtctg
    13261 aattttatgg aaaaaaaaga aggcataata tttgttacag caatatggat agttgcattt
    13321 attggtataa taataaaaat attttggatg gatgcaccta gatggttatc taccagtata
    13381 tatttactta tggggtgggc aattgttttt gatataaatg cattcaattc aattcctaag
    13441 gattgcctta gactattaat tatggaaggt gtatcttact ctataggtgc aattatttat
    13501 ataattaaaa agcctaatat aagtcctgag tttggatttc atgaaatatt tcatattttt
    13561 attatgatag gttctttatt tcacttttta gcagttttat tgtatgtttt atagttttaa
    13621 aagatttgat taattgatac taaaattcta caatgaataa aatggaactg ccttatatag
    13681 attatatctt cgacaataag acagttcctt attataaata ttaaattcta cttataataa
    13741 aattttgata aaaatagtcc attcaaaatg cctattccat aattccttta atgtactttt
    13801 catttacgac atatagtttg aatttatgta ctataattat atcctctaaa ttctctgaaa
    13861 cactaacaat tctgacacat ttgtttctaa tttctacagg taaatctaaa tcatttgtta
    13921 aattcacata gtcatcatat ttatacataa aatcatccct ttacattaag atatacttat
    13981 tatactatat tttaataagt ttttttaaat tattacaatt tttcccgaaa tttcattttt
    14041 tatacataaa atttccaaat taggtaaaga ttaaattttt tattgtataa acaaaagtta
    14101 catataaaat attttattca attttttaaa taactattgc caatttttga aaaatatatt
    14161 attattaata gtaacaaaaa actgtaaatt tagaatatta ataaaaatta tttgggagga
    14221 aattatcatg gtgagattaa atatagtaaa attaaataca aaattaaatc atcaccatca
    14281 tcatagatta aagggattgt aatatgaaat taattcatag acacaagccc tgtttttagt
    14341 gtaattggtc ttgtatctat gatgggaagt aattttaaga gaaaattata gccatatagg
    14401 tataaagcct atgtggcttt tttattgttt taaatttgca aatataagag taaatttaat
    14461 gaagagggtg agaatgtgaa atttttgagg attgaagatg aggttattta ttctaaaaaa
    14521 agatataaat taaaaaggga aatagataaa ctttttttgg atgaagaata ttttcaaata
    14581 gaaccacaat tatttgaaga atatgatgaa tttacaacta taaataataa aattccagaa
    14641 gaatctatgg taaaggttgt aaatggaaaa gtaatggtac ttagagctga tataactaca
    14701 agtataataa aaagccttgt accaagatgg gaagatggtt taaagcttaa gcttttttat
    14761 aattcatcaa tatataaaaa taaaaataca gttggaataa aagagataag acaaataggt
    14821 tgtgagtatc taggagaagc ctctgtagaa gcagatagag aagtagtgaa attagctctt
    14881 aagatacttg aaaaatacaa taataatttt attctagagg ttgggagtag caagtatatt
    14941 catggtttgt tagaagaatt aaatttaaat aagaattgtg aaaatcaaat taaaaattta
    15001 ctatatacga agaacactca tgaactaaaa gtatatattg aagaattaaa aattaagcgt
    15061 gaagtaaaag agttattatc aaatatttta agtttacaag ggaatttata taatgttatt
    15121 gaaaaatcaa acaagttcta ttgtaataat aagatgaagc aagctcttga agaattaaag
    15181 caagtaaata atttaattga ggaatgtaat tttttagata aggctagatt tgatttatca
    15241 atgattacta tgcttgacta ttatgaagga attatgttta gaggatacta cccaaactca
    15301 tataaagaaa ttcttagtgg cggaagatat gattctttaa ctaaagagta tggaaaagaa
    15361 attccagcca ttggatttac actaagtgtt gatgagttaa tgaagtatgt atataagtaa
    15421 agtttagaag gagggattgc tttggattat ttgactatag cactagcaaa aggacgaatt
    15481 gaaggggaat catttaaaaa atttaaaaaa atgggtctag gagacagtat agacacagat
    15541 acgagaaaac taatttttaa agatgaagaa aataaaatta tatatataca tgtaaagcca
    15601 tcagatgtag ttacatatgt tgaaaaagga gtcgctgacc tcggtatagc aggtaaagat
    15661 actattttag aaaatgagac agatgtatat gaaatatatg atttaggttt tggaaaatgt
    15721 aaatttgctg tagcaggatt aaagggagat agcatatata gagaagatga atatttaaaa
    15781 gtggcaacaa agtatcccaa tatagcaaaa aagtatttta aagagaaagg tcaaaaaatt
    15841 gaaataataa aattaaatgg ttctgtagaa ctagctccaa tagtagggtt gtcagatgta
    15901 attgtagata tagttgagac tggcaataca cttaaagcaa atggtcttga aatattagaa
    15961 gacatatgta atataagtgc tagaattata tcaaatagag ctagctatag atttaaatat
    16021 gaacaaattc agaatataat tcgtttattt gaagaacttg ataattaaaa tataattgag
    16081 ctttataagg agggatttaa gttgagagaa aaagaaagca taagagagtt aaggggatat
    16141 gaaccaaatc acgtaaactg taaagtaaaa cttgatgcaa atgaaggaag taagaggttg
    16201 tttaaatacc ttattaaaga aatttcagat agtgatatag atttaaattt atatcctgaa
    16261 gattcttata gtgatttgaa agaatctata atagattaca taaatatttc tggagtaaat
    16321 aagaaaaatc ttctagtagg aaacggttca agtgaaataa ttgatttaat aatacatact
    16381 tttgtagata aagatgaagt aatattgagt ttctctccaa gttttagtat gtattctata
    16441 tatagtcaga taaatgggtc taaatttata ggtgttgaaa gtgatgaaaa tttagttata
    16501 aatatagata atgtgattga aaaagtaaag gagaataatc ctaaaatagt aattgtatgt
    16561 aatcctaata atccaactgg aacaatatta aagagggaag agataataaa gcttttagat
    16621 tcaactaata gtctagtggt tttagatgaa gcatatatgg attttggaga agaaagcatg
    16681 ttaagtgatg tttttaagta tgataatcta atagttctta gaactttatc aaaggcattt
    16741 ggattggctg gaataagaac aggatatatg ttatctaata gtagtttaat aaattctgtt
    16801 gagaaagtaa gacctccata taatttaaat tcattatcag actttattgc tacaagagca
    16861 cttagaaata aagatgtggt aaaggcttat ataaaggaag taaaagagga aagagaagtt
    16921 ttatatgaag aaatgattgg tatgggaatt aaagcataca aatcacaagc aaattttata
    16981 ttattttatt ctgaaatcga aaatttatca caaaaactta ttgatagagg tgttttaata
    17041 agaaaatttg gtggaaagtt agaaaattat tacagagtta caattggtga taaagaagaa
    17101 aattctatgt ttgttggagc tataagagat attttgaaaa aggagaaata ggtatgagaa
    17161 tttggaaggt agaaagaaat actcttgaaa cacagatttt agtagaatta aatattgatg
    17221 gttctggtaa agctgaaata gatactggaa taggattttt agaccatatg cttaccttaa
    17281 tgtcatttca tggcaagttc gatttaaaag tgatttgtaa gggtgataca tatgtagatg
    17341 accaccatag tgtagaagat ataggtatag ctataggtga agcatttaaa aatgcactag
    17401 gtgacaaaaa aggaatacga agatattcta atatctatat acctatggat gaatctctat
    17461 caatggtagc aatagatata agcaatagac cttatcttgt atttaatgct aaatttgata
    17521 cccaaatgat tggtagtatg agtactcaat gctttaaaga attttttaga gcttttgtaa
    17581 atgaatcgag agtaacatta catatcaatc tcttatatgg ggaaaatgac catcataaga
    17641 tagaaagtat ttttaaagca tttgcaagag ctttaaaaga gggtagtgaa atagtttcta
    17701 atgagatagc atcttcaaag ggggttttgt agaatgaata taatagtaga ctatggtctt
    17761 ggaaatatag attctgtgtc taggggtttt agaaaagctg gaatagaaac taaaatttct
    17821 agtgatatag atgaaataaa acaggcagat tcacttatac ttccaggtgt tggagctttt
    17881 agagattcta taagtgcctt agataaacta ggattgatac caataataaa ggagcatgtt
    17941 tctaagggta aatttatgat aggtatatgt ctaggaatgc aattacttta tgaaaaaagt
    18001 tatgagtatg gagaatatga aggattagga cttataaaag gaagtattga taaactggat
    18061 ataagtttaa aagtgccaca tatgggatgg aataatctaa aatttaataa ggcaaatgat
    18121 gatatactta aatatataaa tgaagatgat tatgtatact tcgttcactc atattatgca
    18181 aattcatcaa atgaagaact aattgcattt tcagaatatg aaaagaaaat ccctgctatt
    18241 gttagaaaag gcaatgtata tggtatacaa tttcatcctg aaaaaagtgg agaagtaggg
    18301 ttaaatatat taagagcata tggggagatg ataaaatgat aatatttcca gcaatagata
    18361 taaaagataa taagtgtgta agactcacac aaggagaatt tgacaaagta aatgtatatt
    18421 atgataatcc attagaagta gcatataaat ggaaaaatga aggagcagaa tatatacata
    18481 tagtagattt aaatggtgct agaagtgaat ttggtgtaaa tacaaaaata attgaggaca
    18541 tagcaaacaa tatagatata cctattcaag ttggcggtgg agttagggat aaggaaaaag
    18601 tcaaaagttt aataaatgct ggtgttacta gagtaatatt aggtagtata gcgattgaaa
    18661 atttgaattt agttgaagaa ttggtcaatg aatataaaga gaaaattgta gtttctatag
    18721 atgctaaaga tggaaaagta gcagttaggg gatgggaagt tgtaagcaat gtagactcat
    18781 taacattatg taaacaactt gaaaagatag gtgtacaaac tattgtttat acagatatat
    18841 caaaagatgg gatgttgcaa ggtccaaatt ttgacatata tgaaagaata gcaaaggaaa
    18901 catcactaaa tgttattgct tctggaggcg taacttctat agaagacgta aaaagactaa
    18961 aagctatgaa cttatatggt gcaataatag gtaaagcgct ttatgataaa aagatagact
    19021 ttaaggaggc acaacaatta tgcttactag gagaataata ccttgtctag atgtgagaaa
    19081 tggaagagtt gtaaagggga aaaaatttaa agatatagta gatgttgata gtccagaagt
    19141 acttggaaaa ttttatagtg attgtggtgc agatgaactt gtattctatg atataactgc
    19201 atcaaatgaa gagagaaaga catctttaga atttgtgaca aaagttgcag aaaatataaa
    19261 tataccattt tgtgttggtg gaggagtaaa taaattagaa gatttcactg atattttaag
    19321 aaaaggtgct gataaagttt ctataaattc atcagcagtc aaaaatcctg aattaataag
    19381 ggaagcttca ttaaaatttg gagcacaatg tgttgtttta tcgatagatg caaagaaaaa
    19441 tgaagagggt tcatggagcg tatacgtaaa aggtggaaga gaaaaaacta atctggatgc
    19501 aattgaatgg gctgttaaag gtgtagaact tggagcagga gaaatcgttg taaatagtat
    19561 ggatgaagat ggaatgaaaa atggatatga tatagaatta ttatcaaaga taacttcttt
    19621 agtaaatgta cctgttatag catctggagg cgctggaaaa aaggaagatt tttatgaggc
    19681 ggttaataaa tccaatgtag atggaatttt agcagcatct gtttttcatt ttggcgagat
    19741 aaaaataaac gatttaaaga aatatttaaa agacatgggt gtagaagtaa gattataagt
    19801 taaatactaa aaggagatta gaaatatgga taataagtgt aacaatgtat acagtgatga
    19861 agtagagaaa tttataagaa gtataaagtt tgatgataaa gggttagtcc ctgttgttgt
    19921 tcaagaggta gttagcaaag atgtactgat gttagcatat atgaataaag atgtgataaa
    19981 gaaaacctta aaagataaag tagcttgcta ttttagtaga agtagacaag aactttgggt
    20041 taaaggtgag acatctggta atactcaaaa agtagttaag atgtcttatg attgtgatgt
    20101 agatactata ctactttttg ttgaacaaac tggtgtagct tgtcatacag gcaattattc
    20161 ttgtttttac agagacttgt ttgatgatag ttcaaaaatg gagcttgaag tacaaacaaa
    20221 tatattgaaa gaattatatg atttaatcaa tgaaagaaaa aataatccag ttgaaggttc
    20281 ttatactaat tatctttttg aaaaaggaat agataagatt cttaaaaaag taggtgaaga
    20341 gagtagtgag gtaattatag catcaaaaaa tactgataaa agtgaactta tttacgaaat
    20401 tagcgattta gtatatcata cattggtttt aatgatagaa aaaggtgttg aaattgatga
    20461 aataaaaaaa gaattactta aaagaagaaa atagaataag atagattaat gggtaataag
    20521 aaaatatacc acttttaata aaaagtggta tattttttat tttatatttt gatttataga
    20581 ataatattta aattacttga taaaattaac tatatatata atttattgat aaaataattc
    20641 tagtac
//
LOCUS       DAEHWO010000076        20551 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEHWO010000076 DAEHWO010000000
VERSION     DAEHWO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20551
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.076"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            69..3017
                     /locus_tag="KNP54_003071"
     CDS             69..3017
                     /locus_tag="KNP54_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0893936.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            2995..3459
                     /locus_tag="KNP54_003072"
     CDS             2995..3459
                     /locus_tag="KNP54_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0893937.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            3572..3874
                     /locus_tag="KNP54_003073"
     CDS             3572..3874
                     /locus_tag="KNP54_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0893938.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            3936..5300
                     /locus_tag="KNP54_003074"
     CDS             3936..5300
                     /locus_tag="KNP54_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBF0893939.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            5335..5808
                     /locus_tag="KNP54_003075"
     CDS             5335..5808
                     /locus_tag="KNP54_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893940.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            5980..6630
                     /locus_tag="KNP54_003076"
     CDS             5980..6630
                     /locus_tag="KNP54_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBF0893941.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            6804..7736
                     /locus_tag="KNP54_003077"
     CDS             6804..7736
                     /locus_tag="KNP54_003077"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBF0893942.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            8010..8723
                     /gene="ispD"
                     /locus_tag="KNP54_003078"
     CDS             8010..8723
                     /gene="ispD"
                     /locus_tag="KNP54_003078"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBF0893943.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            8720..9205
                     /locus_tag="KNP54_003079"
     CDS             8720..9205
                     /locus_tag="KNP54_003079"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBF0893944.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    9300..9508
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9572..11287
                     /locus_tag="KNP54_003080"
     CDS             9572..11287
                     /locus_tag="KNP54_003080"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBF0893945.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFNRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            11409..12854
                     /locus_tag="KNP54_003081"
     CDS             11409..12854
                     /locus_tag="KNP54_003081"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBF0893946.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            13292..14773
                     /locus_tag="KNP54_003082"
     CDS             13292..14773
                     /locus_tag="KNP54_003082"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBF0893947.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            14994..15149
                     /locus_tag="KNP54_003083"
     CDS             14994..15149
                     /locus_tag="KNP54_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893948.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            15294..16691
                     /locus_tag="KNP54_003084"
     CDS             15294..16691
                     /locus_tag="KNP54_003084"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBF0893949.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGESGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            16676..17089
                     /locus_tag="KNP54_003085"
     CDS             16676..17089
                     /locus_tag="KNP54_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBF0893950.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEVEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            17195..17953
                     /locus_tag="KNP54_003086"
     CDS             17195..17953
                     /locus_tag="KNP54_003086"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBF0893951.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            17966..18703
                     /gene="rlmB"
                     /locus_tag="KNP54_003087"
     CDS             17966..18703
                     /gene="rlmB"
                     /locus_tag="KNP54_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBF0893952.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            18706..19233
                     /locus_tag="KNP54_003088"
     CDS             18706..19233
                     /locus_tag="KNP54_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBF0893953.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            19298..19945
                     /gene="sigH"
                     /locus_tag="KNP54_003089"
     CDS             19298..19945
                     /gene="sigH"
                     /locus_tag="KNP54_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBF0893954.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            20019..>20551
                     /locus_tag="KNP54_003090"
     CDS             20019..>20551
                     /locus_tag="KNP54_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBF0893955.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSAL"
BASE COUNT         8499 a         2149 c         3850 g         6053 t
ORIGIN      
        1 taagtacaaa aaaaacaata tatggcatat aagttgctat ataaataata aggagggaac
       61 aattataaat gaggcaaaga ataaaaaact taattgaaaa tgaagataag aaaaatcctt
      121 taacagatga agcgatttca agtaggttaa atattcgaag agaagatgtt acctttttga
      181 gaaatgagtt aaaaatagaa gattcaagac aaagaagaaa agttgtttta attaaagcta
      241 taaaagatat tttaaaagaa gaaaaaacta taaataaaaa tgatataaca agaagattaa
      301 acagcattgg gtttacagta tcaagattta cagtcataca atacttaaaa gagattcaag
      361 attctggtga cctaaaactt gataaagaga gtgatgataa aaaagaagaa ataatcaata
      421 atagagaaaa taaagatata gcatttgata aactcatagg tagtagtggt agcttaagta
      481 caattataaa actagccaaa gcagcaattc tttatccacc tcatggtctt catactatta
      541 ttatggggcc aactggtgtt ggaaagagtg agttagcaga gtgtatgtat aaatttgcag
      601 tagaatcatc cagattccct aagaatgcac catttatagt ttttaatgca gcagattatt
      661 cagagaatcc acagcttttg ctatcacagt tatttggaca cgttaaaggt gcttttacag
      721 gagctgatga gaacaaagaa ggattagtat caaaggcaga tggaggaata ttgtttatag
      781 atgaaataca tagattacct catgaaggtc aagaaatact atttcaactg attgataaag
      841 gtatggtcag aaagttagga gaaacaagac taacacataa aatagatgta atgattattt
      901 cagcaacttc tgagccaata gattctcatt tacttaatac atttaaaaga cgtatacctg
      961 taacaattga aataccagaa ttagttgcaa gaccattaaa tgagaggttt gacattataa
     1021 ataatttctt cttaatagaa gctcaaagaa tgggagcaaa catacatata aagtcagatg
     1081 tattaaaagc tcttatgctt tacgattgta taggtaatgt aggtcaactt agaagtgata
     1141 ttcaagtagc ttgtgctagg ggactattaa accaacttac aaacaaacta aaagaagtaa
     1201 atataagcat atcagatgta cctggatatg taaaacaagg tcttataaaa atcagaaatt
     1261 gtagaggaaa aatagaaaat tatgtagatg gggatttaat tatagactca aatcttcaag
     1321 gtgagataga aaagaaaaat gaagatatat atacttttcc agatgaaata tacaaactta
     1381 ctgaaagaag acatattgat ttattggaac aaggtttaga ttttgatgtt ataaatagaa
     1441 tcattggagg agaattagaa agttgcattc aaaaatacat aaaacaagtt aaaaaagttt
     1501 ctattagtaa caatcttcca gatataagtc caattgttgg aaaatatatc gtagagctaa
     1561 cttatgaagt aatcaaaata gcatcacaat acctaagttc actagaaccg aatctacatt
     1621 tatgtttagc agttcaccta aaagcagctt ttgagagatt aaaagaagga aaagtaatat
     1681 caaatgctca tttgaaagaa ataataggaa attatccact agaatattct gtagcagaaa
     1741 aggtagctca atatttaaag gaaagatata acataaactt accaaaagaa gaaataggta
     1801 taatagcaat atattttaaa atgagtagta gaagagatat gtctgaacaa aaaaagatag
     1861 gtgtacttct tatggctcac ggaagagtag catcttctgt atgtgaggtt acaaataaac
     1921 tattaggaat taatcacgca aggtatttag atatgccatt tgagaagaaa ccggaagaaa
     1981 tgattgaaga agctactaca ataataaaag atattgatga aggtagaggt gtgattatat
     2041 tagtagatat gggttcactt tcatattttg gagatattat ttctggaaag actggaatta
     2101 atataaggac aatatctaga tttgatacat tgctttctat agaggttata cgaagagcag
     2161 ttttaccaga tttaacaata gacgagatag ttgatgaagt taaaggtata gagccacaag
     2221 taaaagaaaa ggttagtaaa tgtaataata caaaagtaga ttttagaaaa cctataattt
     2281 taacattatg tattactgga ttagggggag cttgtaagat aaaaaaaatc ctagaggaaa
     2341 atattaaaag tataactgaa aaggttgata tagaacctat aggtatgatt gaatatccaa
     2401 gtcttgattt agagataaaa caaataagca atgataaaaa tgtaatcgcc atagttggaa
     2461 caattgaccc tcagatagca aatatccctt tttttagtct agtagacata aatgataaag
     2521 caaagttaaa tcaaataaat aacctaattg atacaaatca aattggtgaa acaaataaaa
     2581 aatatgaatt atcagattta atacataaag aagatatatt tgtggattta caggttaaat
     2641 caaaagaaga agttctaaaa tatatgagta aaaaacttag agagaaaggt tatgtgacaa
     2701 aaaatttcta taaaaaagta gtggaaagag ataacttatt tccaactgaa ttatcagatg
     2761 aaatagcaat acctcacaca gatggaatag atgtaattag gccagctata agtatagcca
     2821 tcttaaagaa gcctattgtg tggagtaaaa gtaaagtaaa aataatactt ttattagctg
     2881 tagaccaaaa gtgttttaat ccattaagca ctctactctc atttatagaa acagatgaat
     2941 ttaagaagat aaaaaacatt aaagatagag attttattag ggagatgata ttagatggag
     3001 tcaatgaaaa taattagtag caatttaatt tttaaaaata ttgaagtgtc taacaatgaa
     3061 gatgcattaa agtttttggg acaacgtttg tttgacgaac agtatgtaaa agaaagctac
     3121 atacaagctg ttgtagcaag agaaaaaaag tatgctacag ggttaccaac agaaatatac
     3181 ggagtggcaa taccacatac agatatagta catgtaaatg agccaggaat agcaattgga
     3241 atactgaata aacctgtaaa atttataatg atgggtacag acgatactga aattgatgta
     3301 aaagttgtat ttatgttagc agtgaaagag ccacaagaac aattgcaact attagaaaaa
     3361 cttatgacta tatttcaaga taagaatata ctaaataata ttgttgactt aagtgaagaa
     3421 agtgtgagtg atttattaaa ctctaaattg aaaaattaaa catgtaaagt atattaaaaa
     3481 tgtaaaatta aacatgcaaa gtatgttaaa aaatataaaa agattattaa agatttctaa
     3541 ctatagatat ctttaaaata aaataatttc aatgggggtg actaatgtgg ctaaaaagat
     3601 attagttgca tgtggaacag gagtatgtac ttcaacaatt gctataaaca aattaaagaa
     3661 agcacttcaa gacattggta aattggatat ggttaatatt acacaatgta aagtagtaga
     3721 agttgcatca aaagcacctg attatgattt aataatttgt actacacaag tatctagtag
     3781 tataaaaaca ccagtgataa atggattacc ttttttaact ggtgtcggaa tggataaatt
     3841 aatcaatgat gtattagaag agttagaatt ataattaaaa aaattaagga acatggtctc
     3901 taaaatcata agttttagag acttaaaatt aaataatgga gggtctttat atggagatat
     3961 taaatttcat tgttggtcta ggtgcacaag taatgatgcc aataataata tgtatttttg
     4021 gtttgatatt aggtacaaaa ctaggaaaat ctttaagagc tggtttaact gtgggagttg
     4081 ggtttatagg tcttaacact attatagctt tgctaacaga taatttaggt ccagctacac
     4141 aacaaatggt taagaattta gggctaagtt tatcaataat agatgtagga tggccagcag
     4201 catcagctat agcttttgca tcaacagtag gggctttaat tattccaata ggtcttgtgg
     4261 taaatatagt tatgctaatt accaatacta ctcaaactgt tgatgtagac atatgggatt
     4321 actggcattt tgcttttaca ggagctttag tggcaggggc tactcaaagt gtaatgtggg
     4381 gagtatttgc agcagtagca aatatggtaa ttgtattggt aatggcagat ttaactgctc
     4441 caggtataga ggaatattta ggtatgccag gtatatctct tcctcatgga tttacacagg
     4501 catttgttcc aattgctata gtagtaaata aattattaga cttaatacca ggcataaata
     4561 agattgagat aaatgctgat acattgcaga aaaaatttgg attatttgga gaacctttaa
     4621 taatggggtc tgtaataggt gtaataattg gtattgctgc gaaatatgat ataaaaggaa
     4681 tattacaatt aggtgtaact atgggagctg tattaatatt aattccaaag atggcagcat
     4741 tattaatgga aggattatta ccagtatcag aagctgcaca ggaatttatt gagaagagat
     4801 ttaaaaacag aggcaagatt tatataggct tagattcagc agtaggaata ggtcatcctg
     4861 ttacattatc agttgcacta gtgttggttc ctttgactat acttatagca gctatattgc
     4921 caggaaataa agttttacca tttgcagatt tagcagtaat tccatttgca cttgtattaa
     4981 tcgtaccaat tacaaaggga aatgtgttta gaacattaat aataggaata attataatta
     5041 cttctggatt attaatcgca actaacttag ctccattatt tacccaaatg gctttaaatg
     5101 ctagttttaa aatgcctgaa ggagcaacta tgatttcaag tatttgtgat ggtgcgaatc
     5161 cattaagttg ggtatttgta aaagttatga actataaagt tattggagga gtagtttttg
     5221 gagttatagc tttaggaatg gctatttaca ataggaatag aataataaat gaaaataaaa
     5281 agctatctat agaagaataa ggttaaaaca attttattaa ggagtgtata ggttatgaaa
     5341 aaatataaat atgattctaa aagatactta ctcagtgtta caataccagg attttttatg
     5401 attttaatat tgatttatgc actgtttaat aactatacaa attttaattt gaatatatat
     5461 agtttgttaa taattgtctg tacttatggt atattcaata cttttatatc atcaagtaat
     5521 cctaaaaaaa ttattattga tagcaaatgt atacatttta cctcatttat gactacacat
     5581 aagtatgaaa ttaaagatat agaaaagata agaataagag aattttataa taaaaaaatt
     5641 tatctaaaaa ttaatgatgg aaaacttttc aaaggtaggt attggataag aacaaatatg
     5701 tttaataata gtatagcatt atatagctat ttcattgagt tggaagagtg cttatatcca
     5761 gattcactaa aatttagaaa taaaaaattt gagaataaga acatataaaa ataaaaaatt
     5821 gaattgaagc ctagcttaat cttttttgat aagatataag tttgaacttt atactaaatt
     5881 tttagaattt tcaatcaaga caataacata atagctaagc aattagaaca caactaagat
     5941 gtataaggca tgtatatgat gaatgggagg atttaattaa tgttattaga gaaattaaga
     6001 aaagaagtat tacaagcatc tttagacctt ttaaactata atttagtgac attaacagga
     6061 ggaaatgtaa gtgggagaga tgaacaaact ggctatatag caatcacccc aagtggaatg
     6121 gattatagaa atcttacacc aagtgatatt gttatagtag atgtagatgg aaatattata
     6181 gatggaaaat ggaaagcatc agtggattta tcagaccact tgtatatata taagcataga
     6241 gaagacataa atagtataat tcatacacat tctacatact caagttgttt tgctatttta
     6301 aatgaaccta tagaatgtgc aagtacaact cttgcaaatg aagtaggggg ttcagtacca
     6361 gttgcaaaat tttcgccacc aacatctaaa aagatgggaa aatgtgttat tgaagcaatt
     6421 ggtgacaaaa gagcatgtct tttagcaaat catggcgtaa ttgcagttgg tccatctgta
     6481 ggacatgctc ttacagccgc tgtaatgtta gaagattcag caaaagtata ttacttagca
     6541 aaatcaattg gcacaccagt gctactgcct gatgaagaaa ttcaaagagc gagagatgta
     6601 ttttttaatg tctatggtca ggataaataa attagataaa attttaaaag taatatgaaa
     6661 atatagatat tcaatgatat taaggagatt tataatgata taataagttt aatagttaag
     6721 aagtaaaata tgaaatgtaa tagtatataa attcatttaa gactaaaaag aataagataa
     6781 aataaaaagg agtctgtatt tctatgtatt acttattaaa caaaagcaca aatccttact
     6841 ttaatttggc attagaagaa tatctatttt taaatgataa atataatgat gatattataa
     6901 tcatatggag aaatgaagaa tccattttta taggtaaaaa tcaaaatcca tatcaggaag
     6961 tatatcatga tgttattgaa aagggagaaa ttcctatttt aagaagaata tctggaggag
     7021 gaactgttta tcatgactta ggtaatatca atatgtcatt catacaaaaa gataggcaac
     7081 ttcatgagat agattttttg gagcatacta agtttatgca aaagatgctt tcaaccttag
     7141 gactagatgt atctataact gaaagaaaag atttattttt aaatgggaaa aaaatttcag
     7201 gctctgcaca gtctataaaa agaaaaaatt ctctttatca tggaactctt ctttacgatt
     7261 cagatttaaa taaattaact aaatatttaa attcaaataa agcaactgaa tcaaatgcaa
     7321 ctaaatctgt ttcaagtaaa gttacaaata ttaagttttt actcgaaaaa gatataaatt
     7381 actttttaga ttattgtgtt gaatatttaa aatctaatat aaagaatata aaagaacttg
     7441 aattggatga agaagatatt aaaagtgtat acaatatagg agaagataaa tataaaaaga
     7501 tagagtggac atatggtaaa acgccgaaat ttcaagtagt gctaccattt aataatgaaa
     7561 gtaaaataaa tatacatgtt aacagatgga aagtatcaaa attttttatt tcttatgatg
     7621 ataatgtaat taatatggac aagttgttag atttgaattt ctttaaagaa gaaataaaag
     7681 agagtatttt agaaaattat ccacattaca tagatttaat caatttaata ttttaatata
     7741 aaacctctaa tttgataaaa ttgtcttata tcaaactaga ggtttttaat attcttgcat
     7801 attaacaacc attacaaaat tgtaaaatta aaaacaacac tattgaaaaa tcaatatata
     7861 ttgtaataaa tatatgtgtt tttcattagc aaatagacat taactattta tacaactgaa
     7921 aatttaatat ataattaatc agatggttaa aataaaaata ttaaaagttt taataaatga
     7981 tggttaaaaa taaaatacga ggtgatacca tgtatagtgt tataattgtt gcagcgggaa
     8041 gcggaaggag aatgaactta gatataaaca aacagttcat aaaattaaga gaaaaagaaa
     8101 ttattgctca tacaattcaa gttttttatg aaaatataaa tatagatgaa atagtggtat
     8161 gtataaaaaa agaagaagaa gattttttta aagaaaatat aataaataag tataacttta
     8221 aaaatataaa aatagcatat ggcggaaaag aaagacagga ctcaatatat aatggtttaa
     8281 aaaaattaga taaaaattgt gatatagtac ttatccatga tggagcaaga ccatttgtcg
     8341 accatagaat aatcaatgaa tctataaagg tagctaaaga aaaaaaggct gtggttgtag
     8401 gtgttccagt aagtgatact ataaagatag tgtcagatgg aacagtacaa gaaactccag
     8461 aaagaaattt gctgtgggca gcacaaaccc ctcaaacctt tgaatataat ctcataatag
     8521 atgcttatga acaagcatat aagaacaatt attatggtac tgatgattca atgttggtag
     8581 aaaatatagg tcaaagtgtc actatggtaa tgggttctta tgaaaacata aaaataacta
     8641 gtccagaaga tttaaatata gcagaacaaa tattaaatat ggaaaaaaga gatgaagtta
     8701 acagtagaag gagaattata tgagaatagg attaggatat gatgtacaca aattaacaga
     8761 ggatagaaaa cttataatcg gtggtgtaga gataccacac gataaaggtt tgttgggtca
     8821 ttctgatgct gatgtattga tacatgcaat aatggattct attttaggtg ctctagcatt
     8881 aggagatata gggaagcatt tcccagatac agatgaagaa tataagggag cagatagtat
     8941 gaaattatta gaacatgtgt ataatctaat aacaagtaaa ggatataaaa ttggtaatat
     9001 agacagtact ataattgctc aaagccctaa gatggctcca tatattgaga gtatgagaag
     9061 taatatatca aaagttttaa acacagacat tgataatata aacataaagg caacaacaga
     9121 agaaggtctt ggttttacag gagcaaaaca gggaatagct tcacaaagta tttgtttatt
     9181 attgttgaca agtcagaata attaatatat tattagtaat aagtttaatg gatatcaagt
     9241 aataggccta tatagaatat ctataatgta tgaatttaag tgaaattaat ataaatataa
     9301 aattagctat gataaagaaa tagtaaaatg atgaaatctt cacagagaga aaacggtggt
     9361 gagagttttc aagaggaagt ctttgaacct gtcttttagc ttaaaggtat aaaaatcttt
     9421 acggtaggaa ccgttatatt cccaaaagag agctattcat atagctaact agagtggtac
     9481 cgcggaaatt aaacctttcg tctctatact tgtatagaga tgagaggttt tttatatttt
     9541 caggaagtta atattcagga ggaatctatt aatgaaaatg tcaaaaatgt ttatgccgac
     9601 attaaaagaa atcccagcag atgctgagat tacaagccat caattaatgg ttaggtcagg
     9661 catgataaaa aaaatgactt caggtgttta taaccaatta ccaatggggt taagagtgtt
     9721 caaaaaaatt gaacaaataa ttagagaaga attaaataaa aaagattgtc aagaaatact
     9781 ttgtgcagcc ttacttcctt ctgaattatg gaaagagtct ggaaggtgga ctgctatggg
     9841 tgaagaaatg tttagactaa aagacagaac agaaagagag tactgtcttg ggccaacaca
     9901 tgaagaagca ttcactgata taataagaca agaaattact tcatataaac aattgccact
     9961 gaacttgtac caaatacaag taaaatatag agacgagaga agaccaagat ttggtgttat
    10021 gagaactaag acttttacaa tgaaggatgc ctatagtttt gatgtagatg ataaaggttt
    10081 agataagtca tatcaagata tgtttgatgc atatgtaagt atatttaata gatgtggatt
    10141 ggagaatagc cctgtacagg cagattcagg agctatagga ggttctacat cagccgaatt
    10201 tatggttaag tcagaagttg gtgaagatga agttgtattt tgtagtggat gtgattatgc
    10261 agccaatgta gaaagagcag aatcttgtaa tctagcatca caaaaagaag aaatgaaaga
    10321 attagaagag gttcatacac caggagcagc tacaataaaa gagttagaag aatttttaaa
    10381 aacttctcca gataagtttg ctaaaacttt agtatatgag gcagatggaa aaacagttgt
    10441 agtcgttgta agaggagata gagaagttaa tgaaatcaaa gtatctaatg ccataggttc
    10501 tgttatagaa tttgctcttg ctacagatga tgtagtgaga aaagtaacta atgcagaagt
    10561 aggatttgca ggtccaatag gtataaatgc tgactatgta tttatagata aagaaattgt
    10621 tgaacaaaga aacatagttg ttggggctaa taaaactgag taccatataa aaaatgctaa
    10681 ctatggaaga gattttgaag gaatagttgg agactttaga aatgttcaag aaggcgacaa
    10741 gtgtatagta tgtggtaagc cacttgaaat agctagaggt gttgaagtag gacatatatt
    10801 taaactagga actaagtact cagaatctat gaatgcaaac ttcatagaca aagatggaaa
    10861 atcaaagcct atagtaatgg gatgttatgg aataggtgtt gaaagaacag cagcagctat
    10921 aattgaacaa cataatgatg agaaaggtat aatatggcct ttgtcagtag ctccatacca
    10981 tgttgtgata gttccagcaa atatgaaaaa tgaagaacaa atatcaatag ctgaaaatat
    11041 atataatgat ttgcaagcta tgggtgtaga agttttatta gatgacagag atgaaagaat
    11101 aggtgtcaaa ttcaatgatt cagaattaat aggaatacct atgaggatta cagtaggtaa
    11161 aaatattaat gaaggtaaag tagaatttaa acttagacat aaagaagata aagagataat
    11221 tgacatagaa gaaataaatg aaaaagtaaa ggcagagttt atcaggaata atgttaggtt
    11281 aggataataa cttaaataag atattgtata gataatcaaa gttgtacttt atagacacca
    11341 ttttatctat atataaggat ataaaatggt gtttttttat aaaacaaata aatgaggagg
    11401 taattaaaat ggcaaaaaat gaaaaacaat ttgttgaaga aataacaaag atggaagatg
    11461 attttccaca atggtacaca gatgtaataa ctaagactga cttagttgat tatgccccag
    11521 taaaaggttt tatggttgta aagccatatg gatatgcatt atgggaaaag atgcaagaat
    11581 ttatggataa aaaatttaaa gaaactggac ataaaaactg ttattttcca ttattaatac
    11641 cagagagttt attaaacaaa gaagcagaac acgttgaagg ttttgctcca gaagttgcat
    11701 gggtaacaca tggaggaaat aaaaaattag aagaaagatt atgtgtaaga cctacttcag
    11761 agactataat atgtacaatg tatgcgaaat ggttaaaatc atatagagaa ttaccatatc
    11821 tttataatca atggtgctca gttgttagat gggaaaaatc aactagacct ttcttaagaa
    11881 catctgagtt tttatggcaa gaaggtcata cgttacatga aacagcagaa gaagcacaag
    11941 aagaaacaat acaacaatta gaagtatata aagcgctatg tgaagaatta cttgcaatgc
    12001 cagttgtagc tggtcaaaaa agtgaaagtg agaaatttgc aggtggtgaa agaacatata
    12061 ctatagaagc tatgatgcat gatggtaaag cattacaatc aggtacaagt cacttcctag
    12121 gtcaacactt tactaaggct tttgatatta cttttgcaga tagggaagga aatttagcta
    12181 atccatacca tacatcttgg ggagcatcta caagacttat aggtggactt ataatgactc
    12241 atagtgataa cagaggttta gtattaccac caagagtagc tccaattcaa gttgttatag
    12301 ttcctatagc tgctaaaaaa ggaaatgtaa tggagactgt tgataaaata tatgctgatt
    12361 taaaagctaa gggagtagct gtagaagttg atgatagaga taactataca actggatgga
    12421 aatttaatga gtgggaaatg aaaggtgttc cagtaagagt tgaaattgga ccaaaagata
    12481 tagaaaataa tcaagctatg gtatttagaa gagatacttt agaaaaggat tctatgcctt
    12541 tagaaggatt agctgatgct atatgtgatt tatttgatgt tatacacaat gatatgtttg
    12601 aaaaagcaag aaaacataga gaagacaata catctatagt tgaaaatatg gatgagttta
    12661 gaaaagcttt agaagaaaag ccaggattca taaagactat gtggtgtgga gatgcagaat
    12721 gtgaagctaa gattaaggaa gaaacaggag caactataag atgcttacct tttgaacaag
    12781 aaaacttagg tcacaagtgt gtgtactgtg gaaaagaagc agatagtatg gtagtaatgg
    12841 caaaagctta ctaaaataca tttaaataaa aactggggta gaaagtattt aatactttat
    12901 cccagttttt tgttttttat gagtaataaa atgtatttgt aactatgtca taagataagt
    12961 catagatact tatattaaaa agaatataat agagaactat ttttaataat tacatattaa
    13021 tgaaagcaaa atattttgtt atatagattt tcaataaagc aaacaataaa tataaatgaa
    13081 tattaataag gagtgctttt aatttttaga aaataaatga cttaaaagaa agatttatga
    13141 aattaaaact aggattttct gatataataa acatgtgtat ttttaaataa aaaggatatt
    13201 attattagat ttgattaaaa ataaacttgc aaaacaatgt actagtttaa tattatagtt
    13261 atattgaata aaatatcagg aggaagtaaa aatgaatgta agagtaaggt ttgcaccaag
    13321 tccaacagga tttgtacata taggtagttt gagaactgct ttatataact atttatttgc
    13381 aaaaaaaatg ggcggagaat atatattaag agtggaagat acagaccaaa gtagattagt
    13441 agaaggtgct atagagaata tgcttaatgc tatgaaatgg gctggggtca accatagtga
    13501 aggtgttata ttagatgata gtggaaaagt agtacaaaaa ggagaatatg gtccatatat
    13561 tcaatctcaa agattagata tataccaaga atatataaag caacttttag atagtggaaa
    13621 agcttattac tgtttctgta caaaagaaag actggatgaa gtaagagatg ctcaaagagc
    13681 agcaggagaa acagctaaat atgatggtca ttgtaagaat ctttctaaag aagaagtaga
    13741 agcgaatata aaagcaggaa taccatatgt tataagatta agattgccag agaatcatac
    13801 aattaagttt acagacttag ttagaggaga tatggaattt aatactaatg acttagatga
    13861 ccaagtatta atgaaaacag atggatttcc aacttatcat tttgcagtag ttgttgatga
    13921 ctatttgatg aaaattacac atgttataag aggagaagaa tgggtatcat ctactccaaa
    13981 acatgtttat ttatatgaag cttttggatg ggaagcacct gtatttgtgc atttaccaaa
    14041 tatacttaat aaagaaaaga aaaaattaag taaaagacaa ggtgatgtag ctgttgaaga
    14101 ctttaagaaa aaaggatatt taccagaggg attagtaaac tatgtagcat tagttggttg
    14161 gtctcctgaa gataatcaag aattgtttac aatggaggaa ttagaaaaag ccttctctgt
    14221 agaaagagta tctaaaagtg gtggagtatt tgatactgaa aaattaaatt gggttaatca
    14281 gcactatata aaagatggtg atgatgctta tctaacagac ttagcaatac catttttaat
    14341 agaagatgga tttataacag aagaagaagc tactaataaa tatgatttct taaagagtat
    14401 gatatcagta cttaaagaga aattacaata tgtaaaagaa gttactgaac atgcaagtat
    14461 attttttgga gataaaatag aggtagaaac tgaagaggga agagagttct taagattaga
    14521 acatatacct actttaatag atgctttgag agaaaaaata gaaaaaacag aggtattaaa
    14581 tgctgagttt gttcaagcta tgcttaaaga aatacaaaaa gagtacaaaa taaaagggaa
    14641 aaatttattt atgggctcaa gaataatttt gacagggcaa atgcatggtc cagatttacc
    14701 aaaagtaatg gaagttttag gaaaagaaac ttgcttaaat agaatagctt atgtaaaaaa
    14761 taatatatta tagtcataaa agtccgctaa tttagaagcg gacttttttt gtgttagtat
    14821 ttggtgaaaa tatctgctta agaaaatgaa ggtatttaag gtaataaatt taatatataa
    14881 aaagcaaagc aaaaatataa ataaaatatg aataataaac taataaaata ttaagcatag
    14941 aagaagggaa tctattattt tagtttgatt taattattaa gggggtaatt actatgtata
    15001 gtaatattga tgatgttaaa aaggaattaa aggagctatg cttagaatat gttacaattt
    15061 tagaaaaatt aaaagatgaa aaaatgatta cagaagaaac ttttgaaaag tgctcttctc
    15121 aaaaaaaaat atttttagaa gaacaataga ggatggtaat agtattatta ttatgtagtt
    15181 tgaaagatag tacgaaaaat gatagtaata ctattattta ttgcaatttt caactataat
    15241 ataatatata atgttaagaa gataatttat aaaaatacag tgaggtgatg agtgtgaaag
    15301 tttataatac attgactaga acaaaagaag aatttgttcc attagaagaa ggaaaggtaa
    15361 aaatgtatgt gtgtggtcca acagtttata actatataca cataggtaat gcaagaccat
    15421 ttataatatt tgatactcta agaaggtatt tagagtatag aggatatgat gtaacttatg
    15481 tacaaaactt tacagatgtt gatgataaga ttataaatag aagtcatgag gagggaatat
    15541 ctcctgaaga agttgcggct aagtatataa aagaatattt tgtagactgt gatgggctag
    15601 gaataaaaag agctactgtt catcctcagg ttacagataa tatacaacag attatagagt
    15661 ttataaaaga gttggaagat aagggatatg catatgcagt aaatggtgat gtatattttg
    15721 atacaaataa gtttgaaggt tatggaaaac tttcaggtca aaaacaagaa gatttagagg
    15781 caggggctag aattgaggtt aatgaccaaa aaagacatcc tatggacttt gttctttgga
    15841 aggcaaaaaa agaaggtgag tcaggatggg atagcccttg gggagaaggt agaccaggat
    15901 ggcatataga atgttctgtt atgtctaaga gatatttagg tgaaacaatt gatatacatg
    15961 caggtgggca agatttaaca ttcccacatc atgaaaatga aatagctcaa agtgaagcta
    16021 gaagtggaaa aacattctca aaatactgga tgcataatgg atatataaat ataaatgatg
    16081 aaaagatgag taaatcaaaa ggtaatttct ttacagtaag agatatatca aaattatatg
    16141 atttagagat agtaagattt ttcatgttat cagcacatta tagaaatcca gtaaacttta
    16201 gtgatgagat gttaaatcaa gctaaagcag gtcttgaaag actatataat actaaagaaa
    16261 aattagaatt tacgctaagt aatttagtag aatctccttt aacagaaaaa gaagtagagc
    16321 ttgttaaaga attagatgac tttagacaaa aattcataga tgctatggat gatgatgtta
    16381 atacagcaga cgcagtaagt gtaatatttg aattagctaa gttaataaat tctaatgtag
    16441 atgaaaattc ttctttggag tttgctaaaa aatgcttaga tgaatttaat gaacttacag
    16501 gagtattaaa tattgtaaat aagaaaaagg atactgtatt agataaagac attgaagaat
    16561 tgatacaaaa aagaactgat gcaaagaaaa ataaagagtt tcaattagct gatgatatta
    16621 gacaacaatt actagatatg ggaattgtat tagaagacac aagacaaggt gttaagtgga
    16681 aaaggatata aaaatggaaa aaactgaatt agttactatg tcaccattag ttttagcata
    16741 cttaggtgat acagtgtatg agacatatat aagagaatat ttaattagac agaatacaca
    16801 aagaaaagtt aatgatttgc ataaactagc tataaagtat gtaaaagcta aagctcaggc
    16861 aactataatt catgaagttg aaattgagtt aactgaagaa gagagtaaaa tttataaaag
    16921 gggaagaaat caaaagtcaa atacttctcc taagaatgca gatattatag actacaaaca
    16981 tgcaactggg tttgaggcat tagttggata tttgtattta aataatgaaa tagagagact
    17041 tcaatatatt atcaataaag gaatcaaaat tattgaaaga gatatgtaaa tattaaagag
    17101 tgttgtctta ataataagta ataaggcaac acttttttta taactaatgt ataataaata
    17161 tatagaaatt agtaatgaga aaggataaaa agttatgaaa gtaaaattaa tatcacatac
    17221 acctgaacca gaaaaagtaa tagctatggc agctaagcta tgttattcac cagttgggac
    17281 agacgaaata gaaaaagact taacagatga aagtatagag aaatttttaa atatgttatt
    17341 aagtataggt catgggtcaa tattagaaca tgcttcattt acattttcaa tagaaggtat
    17401 ttcaagggca tgttcacatc aaattgttag acatcgtata gctagttttt cacaacaaag
    17461 tcaaagatat gttaaattag aacaatttga gtacataatt cctccagaaa tagaaaaaat
    17521 agaaaaggca aaagagttat ttatagactc catgaaaaaa gaccaagaga attatgataa
    17581 gttagttgaa atattgtttg aaaatcatta taatgaccta ataaaaaacg gtaaaaatga
    17641 gaaaacagct aaaagacaag ctgagaagaa agcaatagaa gatgctagat acgtatttcc
    17701 aaatgcatgt gaaacaaaga tggtatttac tataaatgct agaagtttgt ttaatttctt
    17761 tgaacataga tgctgtgaaa gagcacagtg ggaaataaga aatttagctg tggagatgtt
    17821 aagagaggtt aaaaaggttg ctcctatatt atttaaaaag actggtccaa gttgtgtaaa
    17881 tggaagttgt ccagaaggaa ctatgacttg tggagatata gttcaagtta gagaaaaatt
    17941 taaggccttg taggaggtga ataatttggc gagtatagaa ggaagaaatc cggtaataga
    18001 agcaataaaa agcgacagag aaatagataa aatattaatt gcaaattcag ctaaagaagg
    18061 ttcaattaag aaaataatag gaatggctaa agataagaat ataattattc agtatgttga
    18121 taaacataag ttagatgaag taagtacaag tcattcacat caaggtgtaa tagcttatgc
    18181 aagtgagtat aagtattatg aattagatga gctaatagat ttagcaaaga ataaagatga
    18241 agacccattt ttcattatat tagatgagat aacagaccca cataatttgg gttcaataat
    18301 aaggacagca gatgcagtag gagcacatgg agttatcatt ccaaaaagaa ggtctgtaca
    18361 cataactcct gtagttgcca aagcatctgc tggagcagta gaatatatgc cagtttgcaa
    18421 ggtaaccaat atagttaata caataaaaag actcaaagaa gaagggctgt ggattgctgc
    18481 agctgatatg gatggagaaa ctttttataa acaaaatctt actggtcctc ttggtgtagt
    18541 aattggaagt gaaggttttg gaatatctag attggttaaa caaaactgtg actttatagt
    18601 aaaaatgcca atgataggta atgttacatc tttaaatgca tctgtagcag gtggaatact
    18661 tttatatgag atattcagac aaagactgga taaaagtaaa taggcatgaa aaaaaatata
    18721 aatcattact taataataga tggctacaat attataaatg cgtgggacaa tttgaaagaa
    18781 ctggctaaag aggacttaga agattctcga gaaaagctta ttgatgacat tatagaattt
    18841 tctgagttta tgggttataa gactataata gtttttgatg cttataatgt taaaaattct
    18901 cgagaaaaag ttgaaaaaag aaaacacata acaatagttt atacaagaga acaccaaaca
    18961 gcagatagtt atatagagaa atttataact tctttatcaa agtatgatga tgtaaaagta
    19021 gccactaatg actatgcaga acagcaaatg attttaggaa aaggtgctac tagaatgtct
    19081 gcaagagaat taaagttaga gttagatcgt tccaagaata aaatgaagga aaaaaatatc
    19141 ggtttgagga aaaaaattca gcgaaattgg ttggaggaaa ggttagataa agaaacattg
    19201 tcgaaacttg agaacattcg tagaaagcgt tgaaattact aggttcttta gactataata
    19261 tacctataaa tttgttttat atatggggga gatttacatg ttggtagcaa aagaaaaaag
    19321 ttatgagtta gtggacaatt gtcagcagga tgagtataac attgtattaa gagcaagtga
    19381 aggggataaa atagcactag agtacattat tactaaatac agaaattttg taaaggcaaa
    19441 agcaaagtca tattttttaa ttggagcaga taaagaagat ataatacaag aaggaatgat
    19501 aggcctttat aaggcagtta gagattttga tggaagtaag accaattcat ttaaatgttt
    19561 tgcggagata tgtataacaa gacaaataat aactgctata aaaactgcaa caagacaaaa
    19621 acatatacct ttaaattcat atgtttcttt gaataaacca atatatgatg aagagtcaga
    19681 cagaacactt ttagatatta tagctacaag tatagtaaca gatccagaag agcttataat
    19741 tagtaaagaa gagttaaaaa atatagaatc aaaaatgaac gaattgttaa gtgacttgga
    19801 attagaagta ctagaattat atttaaatgg aaagtcatac cagtttatag cggacaagct
    19861 taaaagagat gtaaagtcaa tagataacgc tttacaaagg gttaagagaa aattagaaaa
    19921 acatcttgaa aacagaaatg attaatagta aaatacttac cataagctta ttgtgagcaa
    19981 aattaattta tatcgaaaga taagggagga aattcaaaat ggctaaagct aaatacgaaa
    20041 gaacaaaacc tcatgttaat atagggacaa taggacacgt agaccacggt aaaactacat
    20101 taacagcagc aataacaaaa acattatatg acagatatca attaggagaa gcagtagatt
    20161 tcgcaaacat agataaagct ccagaagaaa gagaaagagg aatcacaata tcaacagcac
    20221 acgttgagta tgaaacacca aatagacact atgcacacgt tgactgccca ggacatgctg
    20281 actacgttaa gaacatgata acaggagcag cacaaatgga cggagcaata ttagtttgtt
    20341 cagcaacaga tggaccaatg ccacaaacaa gagagcatat actattatca agacaagttg
    20401 gagtaccata tatagtagta ttcttaaaca aatgtgacat ggtagatgat gaagagttat
    20461 tagagttagt agagatggaa gtaagagatt tattaacaga atatgatttc ccaggagatg
    20521 acactccaat agtaagaggt tcagcattaa t
//
LOCUS       DAEHWO010000077        19876 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEHWO010000077 DAEHWO010000000
VERSION     DAEHWO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19876
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.077"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            122..1315
                     /locus_tag="KNP54_003091"
     CDS             122..1315
                     /locus_tag="KNP54_003091"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBF0893956.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1521..2639
                     /locus_tag="KNP54_003092"
     CDS             1521..2639
                     /locus_tag="KNP54_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBF0893957.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            2770..3015
                     /locus_tag="KNP54_003093"
     CDS             2770..3015
                     /locus_tag="KNP54_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBF0893958.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            3002..3748
                     /locus_tag="KNP54_003094"
     CDS             3002..3748
                     /locus_tag="KNP54_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBF0893959.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            4033..4908
                     /gene="hslO"
                     /locus_tag="KNP54_003095"
     CDS             4033..4908
                     /gene="hslO"
                     /locus_tag="KNP54_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBF0893960.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            5299..6099
                     /locus_tag="KNP54_003096"
     CDS             5299..6099
                     /locus_tag="KNP54_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBF0893961.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6627..8867
                     /locus_tag="KNP54_003097"
     CDS             6627..8867
                     /locus_tag="KNP54_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBF0893962.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNICEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            9281..10816
                     /locus_tag="KNP54_003098"
     CDS             9281..10816
                     /locus_tag="KNP54_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBF0893963.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVIIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            10832..11593
                     /locus_tag="KNP54_003099"
     CDS             10832..11593
                     /locus_tag="KNP54_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0893964.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            11931..12800
                     /locus_tag="KNP54_003100"
     CDS             11931..12800
                     /locus_tag="KNP54_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0893965.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            13129..13380
                     /locus_tag="KNP54_003101"
     CDS             13129..13380
                     /locus_tag="KNP54_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBF0893966.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            13492..14271
                     /locus_tag="KNP54_003102"
     CDS             13492..14271
                     /locus_tag="KNP54_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBF0893967.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFINYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(14406..15056)
                     /locus_tag="KNP54_003103"
     CDS             complement(14406..15056)
                     /locus_tag="KNP54_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893968.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(15053..15556)
                     /locus_tag="KNP54_003104"
     CDS             complement(15053..15556)
                     /locus_tag="KNP54_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0893969.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(15605..16120)
                     /locus_tag="KNP54_003105"
     CDS             complement(15605..16120)
                     /locus_tag="KNP54_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBF0893970.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            16400..16927
                     /locus_tag="KNP54_003106"
     CDS             16400..16927
                     /locus_tag="KNP54_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0893971.1"
                     /translation="MHEQIDYCERKKIRTIDIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            16911..18314
                     /locus_tag="KNP54_003107"
     CDS             16911..18314
                     /locus_tag="KNP54_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0893972.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(18697..19008)
                     /locus_tag="KNP54_003108"
     CDS             complement(18697..19008)
                     /locus_tag="KNP54_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0893973.1"
                     /translation="MKKIIKSFTSWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(19064..19657)
                     /locus_tag="KNP54_003109"
     CDS             complement(19064..19657)
                     /locus_tag="KNP54_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0893974.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT         7571 a         2154 c         3524 g         6627 t
ORIGIN      
        1 ggaaataaaa aataaatttt atgagaattt aataactaat aattaatata tttaggttat
       61 aataaatatg tgcgtaaaat ctaacaataa gcaataatac cgtaaattta ggaggaataa
      121 tatggatact ttaaaggaac tttttaaaat aggaagtgga ccttcaagtt ctcatactat
      181 gggaccacaa agagcagcag agagatttaa gaatgaaaac ccagatgcag aaagttttag
      241 agcaatatta tatggtagtt tggcagctac agggaaaggt cacttaactg actatataat
      301 tgaaaaaact atagcaccta aaaaagtcga aattgtttgg gaagaagata ttataaaaga
      361 ttttcaccca aatgggatga agtttgaagc tttagataaa gataaaaatg taacagctga
      421 atggactgta tattctgtag gtggagggac tatagcagaa gaaggtcaaa gaaacagtaa
      481 aagcaatagt atatatcact tagatactat ggatgagata gtaaaatggt gcaaagaaaa
      541 taataagact ttggtagatt ttgtgttgga atgtgaacca aaagacataa aagattatat
      601 aaaaactata aaagatgcta tgagaaaatc tattgatgat ggactaagta cagatgaaat
      661 aataccaggc aagttattat taaaaagaag agcaagtaca ttttataatg catataaaaa
      721 agataagagc ttctcaacac ttgtatatgc atatgcacta gcagcttcag agcaaaacgc
      781 ttctggtaat ataatagtta cagcaccaac ttgtggttct gctggagtaa taccaggaat
      841 attctttgca atgcaggatt tctataatta tgatgacgaa aaaataattg aagcactact
      901 tgtagctgga ataataggta atataataaa aactaacgct tcaatatctg gagcagaggt
      961 agggtgtcaa ggtgaagttg gagccgcttg ttctatggca gcagcagcag tagcatactt
     1021 aaaaggtgga actatagacc atattgaata tgcggcagaa atagcacttg aacatcattt
     1081 aggaatgact tgtgaccctg tatatggata tgttcaaatt ccatgtatag aaagaaatgc
     1141 aatggcagct caaagagctt atgatgcagc taattatgca ttattaactg atggctcaca
     1201 ttctgtctcc ttagaccaag ttgttgaaac aatgaaagaa actggtatag atatgatgga
     1261 taagtacaaa gaaacagcta agggtggact tgctaaacat ttcttctctt gctaaaaata
     1321 aaattttcca ataataattc ctctgttttg atttatgaaa caggggaatt attattaatg
     1381 gtgaattatt taataatgca aaatattttt atattcaatt tagcttttta tttttaatta
     1441 gtataacatg ctatataata ttttaattat aaagaaatat agaaatattt tttaataaat
     1501 tagaaattgg aggagattac atgagagagg catcatattt acaagaacaa ctttataaac
     1561 ataggaagtc attaaatcct attgcagaga ttgggagaaa agagtataag acttcaaaat
     1621 atataagaga ttatcttgat aaattaggaa ttgagtatga agtttattta gaaacaggta
     1681 tagtaggtgt aatagaaggt aaaagaccta aaaaagatat tgcttttaga gctgacatag
     1741 atggtcttca tagtgaagaa ggggtaaaac atttatgtgg tcatgatgga catgctacta
     1801 tattacttgg attaattgag tatttaaatg ataataaaga agacttaaat gataatatag
     1861 tatttatatt ccaaccagca gaagaaggtc ctgggggagc aaaagcttta atagatgaag
     1921 gagtgcttag aaaatacaat attgatgaaa tatatgggct tcatatatat ccagagttac
     1981 cagaaggtta tgtaggtaca agagagggct attttatggc tcaaatagga gatattgaca
     2041 tagaaatagt gtctaaaagt ggacatgggg ctatgccaca aaatggtatt gatggtatag
     2101 tgatagcttc aaactttgta agctcacttc aaactatagt gtctagaaat ataagcccaa
     2161 tagacaatgc agtgttgact attggtagaa ttgaaggggg agctagaaga aatataatag
     2221 ctgaaaatat aaagatggaa ggtactatga gatgtttcag cccagaagtg tatgagaaaa
     2281 tgaagcttag agttagagaa cttgctagag ggtttgaatt ggcttataac tgtaaggtta
     2341 atataaatat tatagatgat tatattgctg ttaaaaatga caaggatttg tatcaagagt
     2401 ttgtagaggc tattggaagt gatactgttg tagagttaga gccacttatg atatcagaag
     2461 atttttctta ttatcaaaaa gaagttccag gattattttt tatgttgggt tcaagaaacg
     2521 aagaaaaagg atttgtaaat ggtcttcata atataaactt taattttgat gaaaagatat
     2581 gtgtaaatgc attgaatgtt tattcaaaat tattaaaata caaagaagca atagattagg
     2641 aagataagtt ataaagatta aaaagcataa atacctaaat ttaaaaaaag tgtattaata
     2701 aatacccctt acatatttgt ataaatttat tttaattgac aaaaatacaa ataagaaggg
     2761 gtgatttttt tgaaagaaaa agtacaaaga gaaaagaaga taactaatgg caagaatact
     2821 aaaatattga caaatgatga tataatgaaa tatgagatag cctcagaact aggtcttatg
     2881 gataaagttg gtgaacgtgg atgggcagga cttacagcta aggaagcagg aagaattgga
     2941 ggtatgctta catcacgcaa aaagaggctt aaaaagattg tggaggagca gaataaaaag
     3001 gatgagtcaa tatagtgatt ttgcgtttgt atatgatgaa cttatgaatg aagttgatta
     3061 taatggttgg gttaaatata tagaagatat aatagatagt gaaggtgtaa aagtaaaaaa
     3121 tatattggaa ttggcatgtg gcacgggtaa tcttacaatt ccattgacta aaaaaaatta
     3181 cgatatagct ggtatagata tatctgatga gatgcttagt gtagcaagag aaaaggcaga
     3241 aaaagaagga gtagaattag ttttacttca acaagatata tcagagcttg attttgaaat
     3301 atctgatttg gactgtgtac tttgtgcttg tgatggattt aattatataa cttatgatga
     3361 tgatttggaa aatgtatttt caaagacata tgaattatta aagaaagatg gaatattcat
     3421 atttgatata agttcttttt ataaattagc caacatattg ggaaataaca tgtatggaga
     3481 aaatagagaa gatatagcgt atatgtggca aaattacttt gatgaagaag agaatctaat
     3541 tgaaatggaa cttacattct ttattaaaga tgaatgtgga aagtttgaaa gatttgaaga
     3601 gatacaccaa caaagagcat atactgaaga tgagatagtt gatatgcttg aaaaatctgg
     3661 atttaaggat ataaaatatt atggggattt tacatttgac aaacctagtg aagaaagtca
     3721 aagaatcttc tttgtatgta aaaaataaga tattcttgac tatataagat aattattaaa
     3781 aataaccatg atataaaaat atataaaatg cagttttata gattaaaagt aaagtgatga
     3841 tattttatga tttttatttt ctaataatta taaagtttta tagataaaaa ttaaaatata
     3901 ataactattg cttagtaaaa ttaaaataaa atgggttttg cccaaggtta agatagataa
     3961 gtatttatag attaaaatta aggtagtaat ataataaaaa taagacaatt aacgggacat
     4021 ggaggaatat taatgagaga ttatgtacta agagcgacat caggaaatgg tcaagttaga
     4081 gcatttgtcg caactactag aaatacagta gaagaagcta gaagattaca tgaaactaca
     4141 aaagtagcaa cagcagcact tggaagaaca ttaacagcca catctataat gggattaatg
     4201 atgaaaaatg atagtgataa attgactgta ataataaaag gtggaggtcc aattggaact
     4261 attatcgcca catcagactc taagggaatg gtaaaaggat atgtaggaaa tccacaagta
     4321 gaggttgaag actatccaaa tggaaagtta aatgtagcag cagcagtagg tacagaaggt
     4381 gttgtaaaag ttataaaaga cttaggtctt agagaaccat ataatgggac ttatccattg
     4441 gtaagtggag aaattgcaga agactttact tattattttg ctgtatcaga gcagactcca
     4501 tcagtagtag ctttaggtgt tcttacaaaa gaagatgaag tagagtttgc tggaggattt
     4561 atagttcaat taatgccaga tgcagaagaa gagactattg ctaagttaga ggaaaatgta
     4621 gctaaattac cttctataac taacatgtta aaagaaggaa aatcaccaga ggatatatta
     4681 aatattgttt tggatggttt ggaacctaaa atacttgata cctgtgaagt tgggtttatg
     4741 tgtgaatgtt caaaagaaag agtaaaaact gctttggttg caattggtaa aaaatcattg
     4801 gctcaaataa tagaagaaga taaaaaagca gaagttggtt gccagttctg taataagaag
     4861 tatatgtata gtgaagaaga gttgcttgaa attttaaagg aaatgtagac tataaaaata
     4921 gttgtattga tataagtaat gttatagtaa tatagtaaag tcgtattgat atagtaatta
     4981 aagtataatt tattaataat agacatattt atattaaaaa ataagtttaa taaattttta
     5041 agcttaataa attttaagaa ttaagaagct ttctggctgt aatgtttgca atgttgcagt
     5101 tagaaggctt ttttatttta ttatagttcg tgtcaaagat tgtatgaaac aataaaatat
     5161 tgtaaaataa tttgtatatt tagacctgat tgacacaaag gtttataaga tatttgagtt
     5221 gattatacga aattctatga agtagtaacc ctgtgacttt aatcatggga ggttcagaag
     5281 aaggagaaaa ttttaaatat ggaaagtaaa acgaagtaca taggaataag tatattaata
     5341 ttattgatga tatttttaat tgcaaagaat tttaacggaa aacttgaaat acctattcct
     5401 gagagtaata gtagaaaatt taaatcagca gcagtgtttt atcctcaaca tcaagatgat
     5461 gaggttttat ggggaggaag tgccattgta gatgctataa aacagtgtgg tgttgataat
     5521 gtatatgtgg tattagtatc agatggttct ggagttaacg ttttcaaagc taacacaaaa
     5581 tttagaaatt taactaggaa gcaaaaggaa gaacttagaa ataacgagtt taaatcagct
     5641 ttgagagagc ttggagtgaa acctcaaaat gtgattatac ttgcagatat agataaaaag
     5701 gaaggcacac attatgaatt aatggaaaag actatattgg attttgaaca taagtttaaa
     5761 ggcaatgtga cccatatagc ccatcactat aagtatgatg accatataat gcatagaaag
     5821 aatggggaag ttttaaagaa acttaaacgt gaaggtaaga taaaagatga cttgtatttt
     5881 gttaagccaa aatatgtaaa gtatatacca agaaatgaaa gagctatcta taaagcaatg
     5941 gattttgatg actacaataa ggttaagagt gcttgttatg aatataaggt tgtaaattca
     6001 aagcgtaaaa tgtatggtat aggatatatt tcggcacata gttattttga acatcttcta
     6061 aatgaccctg aacttacgtc tgtattaagt gaagattaat ttcttataag tagtaagtta
     6121 tgtttgataa gttgattgga attttctata gttttgaagg tattggaaat ttagttttat
     6181 ttaaagattt aaagatagag gtttttagtg tttaaaattt taaagttaag ttgaataatt
     6241 gtatagaatt atttgtgaaa gaagaaacag tgtaaaacat agtatcttat ttatggtttt
     6301 aaaatcatag gcaagatact ttttttatgt aactaatacc attttgagat tattaactta
     6361 agaattttat ataatttaac actcatatat aatgatgata tttaggtaga atagatgtaa
     6421 ttacgcttaa ataaaataac tgtatttttt ataaaaatcc aaaccctaca ctatactacc
     6481 agataaaatc tacatgctat aatttgacct gtgtttataa aaaaaggagt aatctaataa
     6541 aatagtattt cacttatgta taactaacaa ctattattac gattttctct aaataattta
     6601 aagaaaaata atgcaggagg taaaatatga acaatgaatt tataatttta aaaggttgca
     6661 aagagaacaa tttgaacaat atttccttaa aaataccaaa aagaaaaata accatattca
     6721 caggggtgtc gggttctgga aagtcatcta ttgtatttga gacaattgca aaagaatcac
     6781 aacgccaact aaatgaaagg tttagtacat ttgtaagaag ttttttacct aagtatggag
     6841 aggttaaagc tgattgtata gaaaatttgt caacaccaat tatcatagac caaagtagac
     6901 ttggtggaaa ttcaaggtca actctaggta ctattacaga tgtaaattcc tttttaagag
     6961 ctttatattc aaggtttggt agtgagtata taggtaatgc caatatgttt tcttttaata
     7021 atattgatgg tatgtgccca cactgtcatg ggcttggaaa aaagctagtt cctaatatga
     7081 accaaattct tgatatgaat aaatcattaa atgaaggtgc tatattgctt tcagggtttg
     7141 gagtgggttc ttggcattgg aatatattcg ctgaatcagg attttttgat attaataaga
     7201 ggatatgtga ttattcagaa gtagaattgg aaaagttttt gcatggtaaa gcagaaaaga
     7261 ttaagataga aaatgctggt caaactaaca tgacatatga gggattaatg gttaaattta
     7321 atcgcctata cttaagtaga gagggagaaa tatctgaagc tactaagaaa aaattgagta
     7381 aacttcttat agaagataga tgtcctatat gtgatggaag aagacttaat gaaagagtat
     7441 ataggtcttt aattaatggt tataatatag cagatttaac tagtatgcaa attgatgaat
     7501 tggctgaagt tattaaaagt atagatgagc cagaagcaca acctttaatt aaaggaataa
     7561 tagaaaagtt aaacagtatc atagatatag gtcttggata tttaacacta gatagagaga
     7621 catcttctct atcaggaggg gaatctcagc gtataaagat ggttaagtat ttaaatagta
     7681 atcttgttga tttaatgtat atttttgatg aaccaagtgt aggacttcat ccaaaagatg
     7741 tgtataaatt aaataatctt ttaaaaaaat tgcgtgataa agggaataca attatagttg
     7801 ttgaacatga cccagatgtt attaagattg cagaccatat tgtagatgta ggaccaaagg
     7861 caggtaagta tggtggagaa gttgtgtatg aaggcagtta tgaaaatcta cttacaagtg
     7921 gtactttgac agggaatgct ttaagtaaat ttcttcctat taaagaaagt gtaagagaac
     7981 atagtggata tttagaagtt aaaaattgta ataaaaacaa tttaaaaaat gtatctatta
     8041 agatacctaa aggtgtattg actttagtta ctggagtagc aggagcaggt aaaagtacat
     8101 tgattaagga tgaattttta aagcaaaatc ctagtgctgt acttatagac caaagccctg
     8161 tttcagcaaa ttcaaggtcg agtttggcaa catatagtgg aattatgaac aacataagaa
     8221 gcatattttc aaaaacaaat ggcgtaaatg cttctttatt cagttcaaat tcagaaggag
     8281 cttgtgataa ctgtaagggt tctggaatag tagaaatgaa tcttgctttt atggagagta
     8341 taaagagtac ctgcaatatt tgtgaaggta aaaaatttaa aaaagaagtt ttagaatata
     8401 ggtttcaagg gaagaatata attgaagttc ttgaaatgtc tgttttagag gcaattgagt
     8461 tttttaattt aaaacagatt aaaacgaaat tacaatgtat tgaaaaaatg ggtattggat
     8521 accttacttt aggacaaact cttgatactt tgtctggagg agagtgtcaa agattaaagc
     8581 ttgctagtga attaaataag gaaagttcag tgtatatatt agatgaacca acaacaggtc
     8641 ttcatatggc tgatattgag aattttataa gtataattga agagattgta gataatggaa
     8701 atacggtcat aataattgaa cacaatatag atgtaattaa aagagctgat tggattattg
     8761 agctgggacc tgaaggagga acaaaaggcg ggagagtaat atttgaaggt attccaaaac
     8821 aattatgtaa caataaaata tcattaacag caaaatatat agtataataa ataaaatata
     8881 ataaaattat aatgatattt taataaatat aatgggtata taaaatgata attaaactta
     8941 acagtaataa ataatgtgag aaatattcaa atttaattaa ataaagtgtc agaaatttgt
     9001 ttaaatttta gtattttaac ggttctgacc ttttttctta tttttatgga gaatatcgag
     9061 gatggagtct ctaatagtta cttttttgtg tctacttgca agtttgatta aaaaatggct
     9121 atacacactt gtgacttcag tcatgggagg ttcagattat aatcttaata tataatttgt
     9181 gaaataattt gatgacgatt tgctgatgta taaacaataa agattaacta cattaaaatt
     9241 taaatcttgt taagtaaaac ttataaaagg agagagatgg atgataaatg atattctaac
     9301 cttattatct gaaagaagtg atttttttat aaagctatcc atagaacatt tgatgatttc
     9361 tattatttct ataataattg cgattgtttt gggtggtata attggtatta ttgtaagtga
     9421 atttcataat tcttctaaac ctatattggg aactatcaat tttctataca ccattccatc
     9481 tatttctatg ctaggatttc tgataccatt ttccggaatt ggaaatacta ctgctgttat
     9541 tgcacttacc atttatgcat tattgccaat ggttagaaat acatatactg gaattactaa
     9601 tgtggataaa aatattcttg aagcagctag gggaatggga agtacagatt ttcagatatt
     9661 gtataaaata aaacttccgt tagccctacc tgttattatg tctggtatta gaaatatggt
     9721 gattatgaca attgcattag ctggtatcgc ttcatttata ggtgctggag gcctaggtgt
     9781 agccatatat agaggaatca cgacaaataa cacaataatg acaattactg gaagtatact
     9841 tattgctcta ttagctttaa tatttgattt tattttaggg ctggtagaaa aattttttca
     9901 acgaaaaaga aaaaagaaaa ataggaaaaa agtttttgcc attctaggaa gccttattct
     9961 tatagtaatt atctttacgt cttatttatt taatccttca aagactcaaa ctattcatat
    10021 tgctactaaa cctatgactg aacaatatat tcttggtgag atgttggata ttttaattga
    10081 aaaaaacaca ggtctaaacg tggaaattac acaaggtgta ggagggggaa catctaatat
    10141 ccagccagct atggagaatg gagaatttga catttatcca gagtatacag gtacaggctg
    10201 gaatatggta cttaagaaaa atgaattata tactgaaagt atgtttagta aactacagtc
    10261 ggaatacaaa actaaactta aaatgcaatg gactggtatg tatggttttt ctaatagcta
    10321 tgcattagca gttagaaaag aagttgcaga taaatacaat ttaaaaaata taacggactt
    10381 aaaagatgta tcttctaaat tgacatttgg agctgaatat gacttttatg agagagagga
    10441 tggatatact ccattgtgta atacatatgg actgaacttt aaagatacag ttgatttaga
    10501 tattggatta aaataccaag ctatcaatga aggtaagatt gacgtaatgc ctatatttac
    10561 aactgatggt cagtatagtg tttcagatgt tgtagttcta aaagatgata aaaatttcta
    10621 cccatcttat caatgtggaa atgttgttcg tttggaagta ttagaggaaa atccagaact
    10681 atcaaaggta tttaagatgg ttggagatat tttgactgat aaagaaatgg ctaaaatgaa
    10741 ttatgacgta gaaaacaaca atttagaacc tagagaagtt gctcgtgagt ttctgaataa
    10801 gaaaggtctt ttataaattg gaggaaatat aatgacacct attatacaat ttaaaaatat
    10861 taaaaaacaa tataatgata aaactataat agataatctt aatttagata tagaaaaagg
    10921 agagtttttg actgtaattg gttcgtctgg ttctggtaag acaacactct taaaaatgat
    10981 taatggtctg attttgccag atggaggaaa tattttgata aaccaaacag atatcaaaaa
    11041 cgaggactta attaaattaa gaagaagaat aggatattgt gtacagggaa gtgttctttt
    11101 tcctcatatg actgttgaag aaaatatttc atatgtacca aatctcctaa gtaaaaagaa
    11161 taaattagaa gtaaaaagtg ctgtaaacaa gtggatggaa atagtgggat tgccaaatga
    11221 tatgaaagtg cgttacccat cagaattgtc aggtggtcag caacaacgtg tagggattgc
    11281 aagagcttta gcttcttctc cagaaatttt attaatggat gaaccttttg gtgcagttga
    11341 tgagattaca cgaaagcaat tacaaaaaga gataaaagaa attcataaaa aaacaggagt
    11401 tacgattatc tttattacgc atgatattta tgaagctttg attttgggaa caaagacttt
    11461 ggtattaaat catggagttg ttcaacagta tgatactcct gagaatattt taaatactcc
    11521 tgctaaccaa tttgtagacc agttattgaa tataagaaaa tctataatag atgatgataa
    11581 tttaaaagaa taaatttaaa tttaaaatca aattgttgtg ataaaaacta ttgatttaga
    11641 gctaacttca agttgtatac ttgaagtgga aaagttagat taaggtatag aagggcattt
    11701 agcagttggc tgtagacgag gtaactgctg aaggtgcttt caataaatgg ctagaacctg
    11761 tatctgttga agattataat aaattgaaat aagaagctca atatacagag tagataggca
    11821 cttcaaatag aagtgtcttt tgtgtgccat aaaataaatc aaaatattag caaagaatgt
    11881 gaaaaacaaa ataaaataat atgctatctt taaaatagga gggatgctat atggataaca
    11941 atttgattac cattgaaaaa actttagatt atatagaaaa acatctttta gatgagatgt
    12001 tagatttaaa tgtaatttct aaagagatag gctattcaaa ataccattta catagaatgt
    12061 ttacatcagt tgtcggattt agtgtacata attatataca aagacgtaga cttactgaag
    12121 cagcgagaat gctaattttt acagaaaaac caattattga gattgcttta atctcggggt
    12181 atgatacaca acgctctttt tcaagagggt ttaaaaaaat gtttaaacgt agtcctaatt
    12241 tttttagaag acatcaagat tttttaccac tacaattaaa atttgatatt cataatagaa
    12301 aaaaattacg tggagatatg gttttagatg ttaaaaaagt taattgtgca gatataaata
    12361 ttgttggcta ttctggtaaa gtaagaaaag gatttcatat tattggaaaa tgctggaggg
    12421 atttgcataa aaataaagag atgatagaaa ataaggtaga tttaggtttt ttaattggag
    12481 ttagtgatta tagcaatttt aaagagattg agaatactcc tacatttaca tacattgcag
    12541 gtgctcaagt agctactttt ggcaaattac ctaatggaat ggaaaaattc gtattaccga
    12601 aaagtaatta tattgttttt acttttattg ggaaaaatga ggatagtatg caaaatgttg
    12661 tagaatatat ctatcaagaa tggttcccta attcaagttg ccagtttaat gaaaataatt
    12721 tatatgactt tgtaaaatat ggagaaaaaa ctgatgagaa tggtttgagt gaaattcagt
    12781 tttgggttcc aatcatttaa aagaaggtat tatgtataaa gtagatggat ttatataggc
    12841 aaagttttac agcagtatgt atttataaat aatttatagt ttgtaggaaa gaaataattt
    12901 tactataaga ttatgataaa atacacaata ctatgacaaa atagtgttaa ataatagatt
    12961 taattttgca taggaaaagt tctataatgg tgtgtattca taaataattt ataatctgta
    13021 ggaaagaaat agttttacta taagattatg ataaaataca caatactatg ataaaatagt
    13081 actaaataat agatttaatt ttgcaaagga taaggtgttt taataaaaat gaatgtagaa
    13141 aacgaattac ttaaaaacct agatagattg catacaacag agttaggcgt tgtaagaatt
    13201 aagaaaaatc tttctttgga gacaaatgat gtagtgaact ggtgtaaaac taaaatagaa
    13261 tctccaaatg ccattattaa tagaaaggga aaaaactggt atataagtgt atatgattgt
    13321 attataacag taaacgctca cagttataca attattacag ctcataaaga aaagaaatga
    13381 attgcaaaat acaaaggtca aaagcatttt ccactgtttg tagtacctat gaagaagtat
    13441 ataaaataat attacttttg aataataatt taaattttgg aggttgaaaa aatgaatgat
    13501 actgtaaaag aaaaattggc agagtcacta acttctgata ctactgatat tttaccttat
    13561 ttgccttatt tattacaaga tttttgggaa ttaggaagtt caccagaaca aatgttacaa
    13621 ttatttagaa agcatatacc ttttaatgag gatacaaaag ttttggattt agcttgtgga
    13681 aaaggtgctg tatctgtgaa gcttgcaaaa gagttgaata tacatatcaa aggtattgat
    13741 ttgatacctg aatttattaa ttatgctaga agaaaggcta ttgaatataa ggttgatgct
    13801 ttgtgtgatt ttgaaatgaa tgatgctaat agttctgtaa aaattgagca tgattatgat
    13861 tgtgtgattt ttggagctgt aggggatatt ttaggtaatt ataaagaaac tataagtaag
    13921 ctattaccta caataaaaag taaggggttc attttaattg atgatgcata tgtagtagat
    13981 aaatctacaa atgaacagct taattttgag agggtgtatc ccacttacaa tgagtggtgt
    14041 atattgttca aagaattagg tctgaagcta attgaatgta taccatgttt agaacttgaa
    14101 aatgatgttg aagaggaaat gaattggatt ataactcgtg caaatgagct aattaaaaaa
    14161 tatccttctc aaaaagatat gtttgaacaa tatgttatta gccaaaaaaa tgaatatact
    14221 gatttacagc aggaccttgt tggagcaact tggattttac aaaaagaata agataaatat
    14281 tagactagat aatcaatgtt atagtgaatt atcccatgtc tagtgaatat aaataacata
    14341 aaaaaccgtc aagatgaata gtttattcgt gcttgacggt ttttagtatt tgttgaagta
    14401 aaattttatt tctttagtat atcactttta gtcaatccat ttgatttagc ttgagtattc
    14461 cattgatgat tccccataag tttatatagg aatctaggga agttaggtga aataaaaata
    14521 gtacttttgt tggaatcatc tatatgtata ttatcactaa gtatattttt tgaaagttct
    14581 tttaatgcaa ttcctaaatc ttttttaggt cctttaccca aaggtacgga ttctagtgaa
    14641 ccaaacatct ccccagctcc aattccaata ccttgaaccc atgtaaagtt gattttttta
    14701 caccaatgct ctatcatttg aattgccaaa tgattatgtt caccttcatt gaatccacag
    14761 ttaactattg catacactgg aataggtttt ttattttgtg tttttaaaaa tttttcacat
    14821 ttctctaaaa aatgaagtaa atgagatgga ataccatcta cataaagagg agatgcgatt
    14881 attaatctat cacaattaag tatggcatta agagcgtcag gatacttaga tgtgctatct
    14941 actttaaatg taaaaacttt attatcattt tgaataagtt gttttaattc agataaaaaa
    15001 tactgtgaat tatttttatt tacttttgga ctaccattta tcattactat attcatatgg
    15061 attcacctct tatatcttgt atattttcat agaaacaaac agagtgttct tttatattga
    15121 aatttatagc atttccattt actaatttcg tagcagtttc tttttcagct tctgtaatac
    15181 aatctccata gaatatagct tttaaattta tctgtttatc atatctgctt ttatgacgca
    15241 tcatattatc ttttattaca aagtatggaa gaatataatt aatgctttta tcaagtacgt
    15301 ttttgacaaa agggctaaac cctccgtaac agcatctgct tattataata attccatcag
    15361 agtcatttat aagtttaccc atgttgctgt aataatcttt tacaacacat tcagaaggag
    15421 ttttaatcca gcaaccaaaa caaccaatac atttgtggat ttcttttgtg tttggaagta
    15481 tttttatatt gtcatcaagt ttgggtaata acttttctaa ttctttgtca gttaaatcat
    15541 gtattaaaag cctcataaag tccatctcct tttattatgt atgtttactt ctaaaaatta
    15601 tatcttatag atttttcagt aaatctttac accaattaat aacaaaatta taatagtcaa
    15661 ctccataaat cattgttgca tacatatatg tatattggtc aacgcaatga ttttcttctg
    15721 catcattttt ttgtttactt aatttattta gaagtaattc tacttcagtt attaacattt
    15781 ttaagtttgt ttcaattatt tctttgggta gatacttgta aaagaatata ttaacaaggt
    15841 ggtcttgctt tgttttagaa aaatttatag gtttctttaa ccattcaaga aatacttctt
    15901 taccagtatt agttatggaa tataattttt ttaatttgct accatctata acttcgtgat
    15961 agtgtatata tccttttgtt tctaatcttt taagtgcagg atagatactt ccaaagctgg
    16021 cgtcaaaaaa gtacgaggta ctttctgaca ttatttgttt taagtcgtat ccacttaatt
    16081 ctttttccat taaaaatcct aaaataatgt attctaacat attacctcct ggtatcaatt
    16141 agatatatat cgattcgata tatttattat tacagataat aaatcttacg tcaagatgct
    16201 ttttaagata agctaaaaag aattaggagt tattgataaa tatgcaaaaa aattaatata
    16261 aaaggtaatt aaatatcaat gaagatttaa aaatagttaa atcaaagtaa gagtctaata
    16321 tataaaattt atagtaactt tatggtttaa atataaactt gcgtgctatt gacaaagtat
    16381 aaaattagca gtaaaataat tgcatgagca aatagattat tgcgaacgca aaaaaataag
    16441 gacaatagat attaaaggag agaatatgag agagctatta aaatgggttt ccattataaa
    16501 tagatacaat acaaattata ttgacaggaa attggcggat attggaatca ataatagcca
    16561 atatttttat gtattacaca tatgtaataa tccaggtatt acacaggaca ctatatttga
    16621 gaaaattctt gtgaatccta gtaatataac aagagctttg gcaaatttag aaaaagaagg
    16681 ctttataaca agagaaccag gtgtaaagga taaaagaaca tggcatttat atcctacaga
    16741 aaaatcttta ggatgttatg atgaaatact aaaaataaca aatgggtatg ttgaggagtt
    16801 gttgagttca tttgagaaag aagagcaaga gttgtttatg tcaatgttaa agaaagttgc
    16861 atttttggct attgatatga atgaagaagc aaaattggag gcgaaggaaa atggaagaaa
    16921 aatataagga gccattggaa tatgaaaagg tttcaaagtt attaactaag tacgcaattc
    16981 ctagtattat agcaatgtta gtaagtgctt tatataacat tgttgaccaa atatttattg
    17041 ggcaaggtgt tggtgtattg ggtaatgctg ctacaaatgt cacttttcca ctaacaacaa
    17101 tatgtactgc aattgcatta ttgttaggaa ttggaggagc gtctaagtgt tcattggaat
    17161 taggtgctaa aaattcagaa aaagctacaa aagcagcagg aaattctata tgcttgatgg
    17221 ctgtttttgg aataagttta tttatagtag tatcaatatt tttaacacca ctattaaaat
    17281 tctttggctc tacatcagaa atactacctt atgcacacac atatacaaaa attacatcaa
    17341 ttggattacc atttcttata atgtccactg gaatgagtaa gttgatactt gcagatggga
    17401 gaccaaaagc ttctatgttt tgtatgttaa taggagcagt tattaataca attttgaatc
    17461 cattattcat ttttgttttt aatatgggaa ttgctgggtc tgctttagca actgttattg
    17521 ggcaacttat atcttttgga ataagtgttc attatataaa gaattttcaa catattaaat
    17581 tacataagaa aagttttaaa ttagatagta taatttataa acatatattt gcgctaggtt
    17641 caagctcatg ttttaatcaa ttagcaatga ctgtaacaca gatagttatg aataatacat
    17701 tggcatatta tggggctagg tcagtttatg gaagtgagat tccacttgct tgtgtcggta
    17761 tcattattaa agtaaatatg atttttatat ctataattat tggtatatca caaggtatgc
    17821 aaccaattat agggtataat tatggggctg aaaagtataa tcgtgtaaaa gaagcatata
    17881 agtttgcagt gggaagtgca actattatat ctgttattgc attcttatgt ttccaattct
    17941 tcccaagaca aattacgtct atatttggta acggaaatga gacttatttt atatttgcag
    18001 aacattattt tagaactttc ttgttcttaa catttataaa tggtgttcaa atagtatcat
    18061 caactttctt tacatcaatt gggaaatcag tgttgggact ttttacttct ttgactcgtc
    18121 aaattttatt tttaattcca ttgatagtaa ttttaccaat gtttatggga attgatggag
    18181 taatgtttgc aggaccaata gcagatgcag cagcggcaat ggtatgtata tactttgcag
    18241 ttcatgaaat gaaatcattg actataaagc aaaataattt gatgagtaac cataataaga
    18301 ttgcagaggt ataagacaat atttaagaag tatagaaaat taatttaaaa aatataataa
    18361 attaatttag gaagtgtaga aaattaatct aaagaagtat aataaactaa tttaggaagt
    18421 atagaaaatt aatctaaaga agtgtaataa actaatttag gaagtataga aaattaattt
    18481 aaagaagtat aataaactaa tttaagaaat atagaaaatt aatttaaaga aatacaatac
    18541 attaattttt aagtaacatt aaattaatgt aagtaaaata atgttcatat gaatatttaa
    18601 aggtgcattt tctgaagcta agtatatgtt gtagagtgtt atgtctctct atcctgtgaa
    18661 gtttaatagc tcaagaaaat gcactattta tgatgattat tttgttttat ttccaatttt
    18721 ggaaataact attctaatta aatctaaaat tataccataa ataagaaaag aaagtataga
    18781 tgctatgtac caataaatcg aaattgaccc tgtaattgtt ctacatggga tttgcatacc
    18841 tgaatccata aaaacaaaaa aactatcaac tctggaaata atagacaaaa taggatttaa
    18901 acctattaga acaatacttt ttgagtcttg accaatttga tgcatataaa tctcaaataa
    18961 tgcaattaaa aaaaaccaag atgtaaaaga tttaataatt tttttcatca aaatacctca
    19021 cataatataa attctgtttg cactatttgc ttactacaac tatttatctc cattcagtca
    19081 catcacttaa ttgtaatcta ggtcttcttg atggttcttc atcaggataa cctaaagata
    19141 ttgctgccac taattgacta tctgtattta accattcaca taattcacga tatgcaaagt
    19201 atacatcaca aatccaaaga ctacctagac ctaattccac agctgtaagc gacatattct
    19261 gaattgcagc tccaattgat tgcatatttg ccatttcata gaatcgttct tcaggggata
    19321 gcttttctaa aggtgattta cctaatatat ttaaaataaa aattgttact ggagcttgtt
    19381 tcatgatttc aactgtgtaa tttgcaccag cgatatgttg acgacttcct ggaagaagcc
    19441 cattatcatt aatttcattt tgaatacctt tgctcatggc tttaagcata gattcttttt
    19501 ccttttcagt gatgacaaca aaacgccatg gttgcctgtt tttagatgaa ggtgcattta
    19561 ttccagcttc aattattttc tctatagttt catgtgaaat gctttgattt ttatattttc
    19621 tgatacttcg tctttttgat atagaatcac ttatcatttt aagtaacctc cgtttatttt
    19681 ttggaaaaat ctatttaatt tttattttct attttaatta ttttagcatt aatcagaaaa
    19741 aaagtcattg attttagtat acaattatta atgattatat taagaattgt atcaaaaagt
    19801 atgtgattat actaagggat tatattaaac attatattta aaattgtatg aaaggttgta
    19861 tttaatatta tattga
//
LOCUS       DAEHWO010000078        19650 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEHWO010000078 DAEHWO010000000
VERSION     DAEHWO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19650
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.078"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            12..1079
                     /locus_tag="KNP54_003110"
     CDS             12..1079
                     /locus_tag="KNP54_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBF0893975.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            1249..3150
                     /gene="cooS"
                     /locus_tag="KNP54_003111"
     CDS             1249..3150
                     /gene="cooS"
                     /locus_tag="KNP54_003111"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBF0893976.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            3143..3616
                     /locus_tag="KNP54_003112"
     CDS             3143..3616
                     /locus_tag="KNP54_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBF0893977.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            3591..4817
                     /locus_tag="KNP54_003113"
     CDS             3591..4817
                     /locus_tag="KNP54_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBF0893978.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRILKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(4956..6143)
                     /locus_tag="KNP54_003114"
     CDS             complement(4956..6143)
                     /locus_tag="KNP54_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBF0893979.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRIVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            6416..7240
                     /locus_tag="KNP54_003115"
     CDS             6416..7240
                     /locus_tag="KNP54_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0893980.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GSNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            7369..8634
                     /gene="gluD"
                     /locus_tag="KNP54_003116"
     CDS             7369..8634
                     /gene="gluD"
                     /locus_tag="KNP54_003116"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBF0893981.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            8847..9437
                     /locus_tag="KNP54_003117"
     CDS             8847..9437
                     /locus_tag="KNP54_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBF0893982.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            9768..10901
                     /locus_tag="KNP54_003118"
     CDS             9768..10901
                     /locus_tag="KNP54_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBF0893983.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKGMEEKDVTNSAIVTMIEF
                     TYAEAPKSMREEHKINCEFLGLIPKDSDKIGVGIEYYDSLLND"
     gene            11817..12839
                     /locus_tag="KNP54_003119"
     CDS             11817..12839
                     /locus_tag="KNP54_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBF0893984.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            13135..14055
                     /gene="pyrB"
                     /locus_tag="KNP54_003120"
     CDS             13135..14055
                     /gene="pyrB"
                     /locus_tag="KNP54_003120"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBF0893985.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            14094..14786
                     /locus_tag="KNP54_003121"
     CDS             14094..14786
                     /locus_tag="KNP54_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBF0893986.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            14779..15681
                     /locus_tag="KNP54_003122"
     CDS             14779..15681
                     /locus_tag="KNP54_003122"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBF0893987.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            15766..16350
                     /locus_tag="KNP54_003123"
     CDS             15766..16350
                     /locus_tag="KNP54_003123"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBF0893988.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            16564..17490
                     /locus_tag="KNP54_003124"
     CDS             16564..17490
                     /locus_tag="KNP54_003124"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBF0893989.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(17542..18432)
                     /locus_tag="KNP54_003125"
     CDS             complement(17542..18432)
                     /locus_tag="KNP54_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBF0893990.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            18620..>19650
                     /locus_tag="KNP54_003126"
     CDS             18620..>19650
                     /locus_tag="KNP54_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBF0893991.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
BASE COUNT         7716 a         2081 c         3491 g         6362 t
ORIGIN      
        1 ggagatttac tatgaaaaat aaattagttt acatatgtat tatgagtcta ttgctatttg
       61 tagtaggatg ttctaataat ccaaataagg aaagtaccat taaaaaagac tctaagaata
      121 accaaagcca agttaaagaa gaaaaaagag aacctgtgaa aaaagatata actataagtt
      181 tcgctggtga tgtaactatg gggaactata aaggttcatc atattatggc agttttgacc
      241 atgaatttaa aagacaagga gaagattaca attattttct taaaaatgta aaacctgtat
      301 ttgaaaaaga tgacttaaca gtggttaatt tagaaggtcc acttactaca gcgtcaaatg
      361 caaaagaaaa aaaatttgca tttaaaggaa agcctggata tgtaaatatt ttaaaatctg
      421 gaagtgtaga ggcagtaagt attgcaaata atcattcaga agattatttt gaagaaggaa
      481 tgaaagatac acagtttata ttggacgaga ataaaataaa ttattttgga ttagggaaag
      541 atgctgttgt agatgtcaaa ggaattaaag tgggtctatt agggtataat ggattatcaa
      601 ctgaatataa tgaaaaaaat ttaaaacaaa tggaagatga tattaagtcc ttaaaaaaga
      661 aatcggatgt tgttgtagtg tactttcatt gggggataga attagattat tatccagata
      721 aaaaacaaaa agattttgct cattatgcta tagacaaggg agcagattta gttatggggt
      781 ctcacccaca tgtgattcaa ggaatagaaa agtataaaaa taagtatata gcttatagtc
      841 tagggaattt ttgctttgga ggaaataaga atccttctga tacagatagt tatatatatc
      901 aacaaacctt tactttttca gataataaat taacttcaat taaagagcca aatataatac
      961 caacttcaat aacatctagt aactccagaa ataattatca accaaaaata ttggatggaa
     1021 gtgagaagga tagagtttta aataaacttg aaaaaataag caaagattta aataaataaa
     1081 atgtaaaaaa aaataaatat atatatttat tttaataatt tatattttgt ttagggtatg
     1141 gtaaatcgtg gtattaaata agtagatttt aatagttaaa ttatagtcaa ttataataaa
     1201 gctatttaat ctactttttt aatataaaaa tataaggggg aatttgtaat ggcttgtaac
     1261 acttgtaaaa tgtgcgaaag tgcagacaag aaattagaaa gttttgtagc ttcaaaggat
     1321 gttgaaacag catttcatag aacagaagat cagaaagtta agtgtggttt tggacttcag
     1381 ggggtttgtt gtagactctg ttcaaatgga ccatgtagag taactcctaa atcaccaaga
     1441 ggtatatgtg gagcagatgc agacactata gtagcaagaa actttttaag agcagtagca
     1501 tcaggagcag cttgttattt acatgtggta gaaaatacag ctaagaattt aaaaaatgtt
     1561 ggaataacta aaggtgttgt taaaggagaa aaaacattaa atcaattagc agagatgttt
     1621 ggaatagaaa gtgatgaaaa gtatgataaa tgtataaagg ttgcagacaa agttatcaac
     1681 gatttgtata aatcaagaga tgataaaatg gaattagtag aaaaaatagc ttatgcacct
     1741 agagtgaaaa agtggaaaga gttaggtata atgcctggtg gtgcaaagtc agaagttttt
     1801 gatgcaatag taaaatcatc aacaaattta aatagtgacc cagtagacat gctagttaat
     1861 tgtttgaact taggtatatc aacaggatta tatggtctta cactaactaa tcttttaaat
     1921 gatgttatgt tgggagaacc agttataaga atggctcctg taggatttaa tgtaatagac
     1981 ccagactaca taaatataat gataacaggc catcaacatt caacatttgc aaatttccaa
     2041 gatagattaa aagatgaaga tgttataaaa ttagctcaat ctgttggtgc aaaaggcttt
     2101 aagctagtag gatgtacatg tgttggtcaa gatttacaat taagaggaga acattatcaa
     2161 gaagtatttg ctggacatgc aggtaacaat tttacaagtg aggctgtttt atcaactgga
     2221 gcaatagata tagttctttc agaatttaac tgtactatac cagggcttga accaatagca
     2281 gataaatata aagtaaaaat ggtttgttta gatgatgttg ctaaaaaagc gaatgcagaa
     2341 tacataggtt tagacagaag taaattagat gaacttagta acactttaat agaaaaagca
     2401 ttggagtctt ataaggagag aagaggaagt attgaaatag atataccaaa agaccatgga
     2461 tttgaacaat ctttaactgg tgtaagtgaa aagaacctga aagcgttttt aggagattca
     2521 tggaaacctc ttattaattt aattgcagaa ggaaaaatta aaggtgttgc agctgttgta
     2581 ggatgttcaa atatgacagc aggaggacat gatgtaaata ctgttgaact tactaaagaa
     2641 ttgattaaaa aagatataat agtactatct gcaggatgtt ctactggagg attagaaaat
     2701 gttggtctta tgtcacctgg agcagaagaa ttagcaggag aaaacttaaa agaagtatgt
     2761 aagactttag gaataccacc agtattaaac tttggaccat gtctagctat aggaagacta
     2821 gaaatagtag caacagaatt agcagctgaa cttggaattg acctaccaca attaccatta
     2881 gtgctttcag ctccacaatg gttggaagaa caagcattag ctgatggagc gtttggtctt
     2941 gcccttggct tacctcttca tttagcttta cctccattta taacaggagg aaaattggtg
     3001 acagaagtat taacagaaaa attaaaagac ttaacaggag gacatgttat agtgaatcca
     3061 gaccctaaat cttcagctaa tcaattagaa gaaataataa tagatagaag aaaaaattta
     3121 gggttaaagg atgtggaatg caatgcatag aatttttata aataaagatt tatgtacagg
     3181 atgtaagagc tgtgtactag catgtatgct aaaacacaat aaagattatg acatgtacac
     3241 tcttgattta gaaaatatag ataatgatag tagagggcat atagaattag atagtaaaca
     3301 taataatcca gttccaattc tttgtagaca ctgtgatgaa cctgaatgtg tattagcatg
     3361 tatgagtggt gcaatgcata aagatagtga aagtggaatc gtttcatatg atgaagagaa
     3421 atgtggttca tgttatatgt gtgtaatgtc ttgtccatat ggattattaa agccagatga
     3481 tagaagcaag cagaacatac ttaaatgtga tttatgtaaa gatgaggagt atcctagatg
     3541 tgtagctaat tgcccaagtg gagcaattga attacagaag gaggaaaatg atgaattatg
     3601 tagtgttagg ggctagtgca gctggtataa atgcagtaaa aacattaaga gaattagata
     3661 aagattcaaa tatagtagta atttctaaag atgaaaacgt atattcaaga tgtatgttgc
     3721 atcacgttat atctgaacac agaattttaa aacaaataaa ttttgttgat gaagatttta
     3781 tggagcaaaa taatgtaaaa tggattgcag gtaagactgt taaaggtata gacataaata
     3841 aaaaggtagt tcagacagaa gacattactg taaattatga taaactttta atagctacag
     3901 gtgcatcttc tgctattcct cctataaaaa atttaagaga tggaaatttt gtatattctg
     3961 tgagaaacat agatgatatt tataaaataa aagaaaaagc acaaaattct aaaaatgtag
     4021 ttataatagg tgctggttta gttggtatag atgcattagt gggattattt aaatatgagc
     4081 agttaaatat ttctgtagct tttatggaaa agtacatttt agatagacaa ttggatgaat
     4141 atacagcatc agtgtatgaa aataagttca aagaaaaagg tgtaaaattt tacccaagtg
     4201 catcaataca agaaattgta ttggataaca gtaaaaatgt tacaggtgtt gcattttcaa
     4261 atggtgaagt tttagatgca gacatggtaa ttgttgctac aggggttaaa ccaaatgctg
     4321 actttttaga tggaacagga atagaatatg atagaggtat aataatagat gatatgtgcc
     4381 aaacaacaca aaaagacata tatgcagcag gagatgttgt aggtaaaaat gctatttggc
     4441 ctctggcagt aaagcaagga attgtagctg cctataatat ggttggaaaa gataagaaga
     4501 tagaagatga atttgctttt aaaaacagta tgaatttcat ggatatacca actatttcta
     4561 taggaatgaa tacacctgta gatgatagct ataaagtgct aactagacat ggaattaatg
     4621 attataaaaa gtttgttttt aaagataatg taatctatgg agcagttata caaggagata
     4681 tttcatatgt aggtgtatta acttatttaa taaaaaataa agttgaaata tatgatttag
     4741 aaaataggat atttgatata tgttatgcag acttttttaa tataaaagaa aatggagaat
     4801 tttgttatag tgtatagtat atacgtggag taaggtttat aaatacagta aatcaataaa
     4861 tagagttatt ctaaaataag aaaaatgaca aatcttattt agaaatagct ctattttttg
     4921 taattaaatt taaattatat tcaatttgta aaatattatt ttgaacaatt atacatatac
     4981 tctctagtta gaggtaaatc attttttata cctttagtga aaagtatttg atgtatatct
     5041 ataataccag tgttgaaagc agcagcacaa gaacaaaggt ataaatccca cattcttata
     5101 aacttatcat caaacatttc tttaatcttt ggaagattct cagagaaatt tttttgccag
     5161 tatagtaagg tttttacata atgtaatctt agactttcta cgtctatagt atgatatttg
     5221 taatcactac aaatatgtat catttctctt aggctaggaa taactcctcc tgggaaaata
     5281 tattttttta tccaagggtc tccataagat tcctgcaatc cacttatata gtgaagtaaa
     5341 aacaatccac catcttttaa aacagcattt acgtttttaa tgaaaagttc atagttttct
     5401 ctaccaacat gttcaagcat cccaacgctt acaattctat caaacataag gtctgatttt
     5461 tttaattctc tatagtccat aagtcttact tcaagatagt cttgaaggtt ctcttcttta
     5521 attcttgcgt taaattcctt aaattgctct tcgctaagtg taattccaac gccgtgaatt
     5581 ttatattttt ttgcagcttc tattagtaaa aatccccaac cacaaccaat atcgagaagg
     5641 ctcatacctt cctctaaatt tagtttagtt aatatgtggt gaactttatt gacttgagca
     5701 tcataaagag tatcattatc atttctaaag tatgcacaag aataactaag tgtcttatct
     5761 aaccataagc tataaaaatc gttgccaatg tcatagtggg catgtatttc tttcttttga
     5821 tgtctcattg aatttgatga gtgcaataga tgttttacag ctgaattatc aatattgaat
     5881 ttgtctattt gttttaaaag tagatttaaa gttaagaata aatctccctc aacttcaatg
     5941 tctctattta tgtaggcttc tccaagtgct aaagatgtac tttttaatag ttcagacttg
     6001 ctaatatcat tatttactat aactttgaac tgaggggagc cctctccaat tagaaattct
     6061 tcctcatctt taagcctaac tagaaatggt gtttcaccaa atttctctaa atagtctttt
     6121 aaaaaatttt ttgtaatatt catattacca gctccttcta atgtaaatcc agtaagtttc
     6181 cctgcttaaa atatattata gtcctttttt taaaaaagta aaattttttc aataaatttt
     6241 ttatttaaag gaaatttatt ttttataaag aaatttcatg ttgtagtata ttttttgctt
     6301 ataaattttg gtactggata taatattaaa ctgttaatga tataataaat ttaatctata
     6361 aagtaaataa aattttgtaa taaatagtta aagctatttt ataaggagat atatgatgga
     6421 agtatatgct ttggttgggt caagtggcac agggaagagc tttaaggctt tagagttcgc
     6481 atatgaaaat gatatagaat atataattga tgatgggatt ttaatataca aaaacaaggt
     6541 tttagctggg atatcggcaa aacaagcaaa tactactata gaagcagtta aaagggctat
     6601 tttttataat ctggagcata gacaagaagt tagagaagca attaaaaaag aaaatataag
     6661 aaaaattctt attattggga catcaaaaaa aatggttaat caaattgtag agagattgtc
     6721 aattggaagg gtttgcaagt ttataaatat acaagatata agtactaaat atgaaataga
     6781 aatagcaaaa caagctagaa aagaaggaaa tcatgtaatt cctgttccag cagttgagat
     6841 aaaaagtatg gcaagtggtc ttagtataaa ttctttgaag agacttttta gaaaaggaag
     6901 taataggaat atggtagttt tagaaaaaac aattataaga ccaactttta gttatatagg
     6961 aaagttttat attagtgctg atgtaattaa acagattatt gaatatgaag tatacaactt
     7021 tggaagcatt gatagaataa ataaaatcaa tatagagaat tgcaataatt ttatgaatat
     7081 ttttgtaagt ataaatatca atgatttaga aactataaaa aaaattgaag acatacaaca
     7141 gacaataaaa aagtctattg agaaaatgac tttagttaat gtacaaaaaa tagatattaa
     7201 cattcataaa attaaaaaaa taaacttcct ccaatgttaa aaaataaact gagaaaatga
     7261 tatactaatt tgcaataaag tgtgctataa ttaaactgta aatttaggaa atggtttttt
     7321 ctaaatggag tatacataat tataacgtat ttataagggg gctttcaaat gtcaggaaaa
     7381 gatgtaaatg tcttcgagat ggcgcaatct caagtaaaaa atgcatgtga taaattaggt
     7441 atggaaccag cagtttatga attattaaaa gaacctatga gagttataga ggtttcaatt
     7501 ccagtaaaaa tggatgatgg ttctataaaa acttttaaag gatttagatc acaacataat
     7561 gatgcagtag ggccaacaaa aggtggaata agattccatc aaaatgtttc aagagacgaa
     7621 gtaaaagctt tatctatatg gatgactttc aagtgttctg taacaggtat accatatggt
     7681 ggaggtaaag gtggaataat agtagatcca tcaactttat ctcaaggtga attagaaaga
     7741 ttaagtagag gatacataga tggaatatat aaattaatag gtgagaaagt tgacgttcct
     7801 gcaccagatg taaatactaa tggtcaaata atgtcttgga tggttgatga gtacaataaa
     7861 ttaactggac aaagttctat aggtgttata actggtaagc cagttgaatt tggtggttct
     7921 ttaggaagaa cagctgctac tggatttggt gttgctgtta ctgcaagaga agctgctgct
     7981 aaattaggaa tagatatgaa aaaagctaaa atagctgttc aaggtatagg aaacgttggt
     8041 tcttatacag ttcttaactg tgaaaaactt ggtggtactg ttgtagctat ggctgaatgg
     8101 tgtaaatcag aaggttctta tgctatatac aatgaaaatg gtttagatgg tcaagctatg
     8161 ttagattata tgaaagaaca tggtaactta ttaaacttcc caggagctaa gagaatatct
     8221 ttagaagagt tctgggcttc agatgttgat atagtaatac cagctgcatt agaaaactct
     8281 ataactaaag aagttgctga atctataaaa gctaaattag tttgtgaggc tgctaatgga
     8341 ccaactactc cagaggctga tgaagtattt gctgaaagag gaatagttct tactccagat
     8401 atattaacta atgctggtgg agttacagtt tcttacttcg agtgggtaca aaacttatat
     8461 ggatactact ggtcagaaga agaagtagag caaaaagaag aaatagctat ggttaaagca
     8521 tttgaatcta tttggaaaat caaagaagag tacaatgtta caatgagaga agctgcttac
     8581 atgcattcaa ttaagaaagt tgctgaagct atgaaattaa gaggatggta ctaagattta
     8641 ctcttaataa ataataggat ataattattt aagatataaa ggggctgtac atagtacagc
     8701 ccttaaatta tgtggcttac aatgaagtaa gctatttttg ttttaactta taaaaaactt
     8761 gataaattat gtaatttaga atgtattttt taccaccaca tgattacaaa ttagaagagt
     8821 tagattagat ttttagacat gaacttatgc attttaaaag caaagacctt aatttaaagt
     8881 atctagtatt atttttaaaa atagtatatt ggtttaatcc atttatatat ataatggaaa
     8941 aatatatgga tttggattgt gaactttatt gtgatgagag agttttaaaa aattgtactg
     9001 tacaacaaaa gcaagaatat gctctaacta ttgtaaattc aatgaaaaga agtacaaatt
     9061 tttcaaataa atttgtagct ggattaaata aacaatctga tattagaaaa agagtaataa
     9121 acatgttcag tgaaaaacat aaaaatggta tcttaagggc tttgattata agcttgtttt
     9181 cttctattac attttttaaa ttcgattcaa ctagtattat tgaagagaat gatttcttag
     9241 agaggtcaag atatacgttt gaaggaaggc aagaagacat gtttgtaaca atagatttta
     9301 tatatgcaga tgtacctata aaacttagaa aagagcatga agaaaactgt agagtcaatg
     9361 gaatagtacc aaaagattca gattcaatag aaattattcc tagattttat aaagattgta
     9421 tggatttaaa aaaataagtt agacttaata ttgatgttga tattatgaat tttttatatt
     9481 taagcaattg aaaattttat tatagattca attttatatg tgtttaagta tgaaatttat
     9541 agatagttga aataattaaa tatgattgat gcataggaat cattactaag ctataattaa
     9601 ttataaggga gtttaaataa attatgagtt acacaattat aaaatgataa aaaatagtta
     9661 tctgttacaa aaaatgtatc tttttaatta ataaagataa tatgaaaact taaaaggcaa
     9721 ataaacttaa acataaaata ctcttaaata agataggaga aaaatgtatg tctaacttta
     9781 ttctaaatgg gatttttaga acagttatag taagtagtct aagcattctt atgatattga
     9841 ttttcaagaa aaatgtattt aaaagattta gcaaaaaatt taattattat atatggatga
     9901 tagttgttat taaattattt ttaccattta catattatac ttttacaata aatatcttga
     9961 gaagtaaaaa acacattaat attaataaca taaatttaga gggatttaat aatgtttcaa
    10021 ctataagtaa taatattata ttgtacactt ggattataac tgtagtagtt tatttaattt
    10081 acactatatt taaatatata aaacttaaaa atttaataaa tgacttatct tatgatgttg
    10141 atgatggaga gattgtaaat ctttataaaa atatattaga agaatttaat ataacaaaag
    10201 atataaaact caaatactct tatgaagttg aaacaccagc attttttaat tcatgtgtgc
    10261 ttttgccacc acatgagtat aaattgaaag agttagactg gatttttaga catgagctta
    10321 tgcattttaa gagtagggac ctttatttaa aatatgtaat cctgttttta aaaacagtat
    10381 attggtttaa tccatttata tatataatgg ataaacatat agatttagat tgtgaacttt
    10441 attgtgatga aagagtttta aaaaatcgaa attcagagga aaaaaaggat tatgctttaa
    10501 caattctaaa tgcaatgaga aaaggttcaa atacttcaaa taaatttata gctggactcc
    10561 ataagcaatc tgatattaaa aagagagtta tgaatatgtt taatgaaaag tacaagaatg
    10621 gtatattaat ggcattaact ttatgtttat tatcttctat tacttttttg aaggttaatt
    10681 caacgagtat tgttaatctt aatatattgc caaaaggaat ggaagaaaaa gatgttacta
    10741 atagtgcaat tgttacaatg atagaattta catatgcaga agctcctaaa agtatgagag
    10801 aagaacataa aataaattgt gaattcttag gtttaatacc taaagactct gataaaatag
    10861 gtgttggtat agaatattat gacagtctat tgaatgatta aataaatatt attttaacag
    10921 atattaatta taaagttttg aatagtaatt tgttgagaaa taaatatatc cttataaaaa
    10981 tagatactta tataccaaga ataaaaaata gtcaagatag tacacaagga tatacttata
    11041 aagaactcaa ataagtgaaa taaattatta attataaggt ttataatttt aaaaaattag
    11101 ataaattcag gtgtaaaata ctataaaaca caattcggaa aagtgtatgt tgaacttcat
    11161 ttaaaatgga atttcaaagt tgctatagta agtagtttaa gcattcttct tatattaatc
    11221 tttgagaata atgtatttaa aaaagttagt aaaaaattta actattgtat attaatgata
    11281 gttgctattg atatattatc taaaaaaatt aagtatgaaa agattactgc taggacaatc
    11341 ttttcatact taatttttaa tatttatatt atccaaaatt ttcatctttt taacttagaa
    11401 tttgagaatc actattagga aataggcttt gatttatgta gggttaaaaa tttcacagaa
    11461 tatctaactt tatactaaat ccatcaaaaa atatacgcca tataaaagcg cataaaaaaa
    11521 cacataaaac aatatttatg cgcactttaa cctcgaatgg tacaaaattc tttactttta
    11581 cagacccata ttatataatt aagtaaataa tgtatattta ggtgacatat tggataagct
    11641 aatttattta ttttattaat ataatgatac tataaaagtt atataaagtg gtttacaaaa
    11701 aagttacaga tagagctttt attaatgtat tgtgtattag tattttatcc ttaggtacac
    11761 ttcacctaca aaatagaatc ataagataat tatgggaaaa ttttaggagg tttatcgtga
    11821 agaaaaagat attaatacca gtatttgcat cagttatggc attatcagta agttcaattg
    11881 taaatgcaga tgaagtaaat gattcatctc aaaataagga tgataaaaca aatactgaat
    11941 taaatttagg tgaatataaa gaagtaaaat ataaagttgc aaaaataaaa gatggagtag
    12001 ctataaagat aagagaagaa ggtcaagttc aaaacatagc ttattctgga gatgaattta
    12061 cggttttagg aactcaagga gaatgggtta aggttaaagt tgaagatggc gaaggttggt
    12121 tagctactag atatgtagat atatctgaag gtgtaggata tactaacgct gataaagtaa
    12181 acttaagaaa agataagagt gaaagttcag aagtaattga agagctggaa aaaggaagtt
    12241 ctttattggt tttggaagat aatggagatt ggttaaaagt taaagatggg gaaacagaag
    12301 gatatgtaaa atcatcttat atatctgata aagctcctgt aatagaagag ccacaagtaa
    12361 acccaagtat tgaccaaaat gtagattcta caaataataa tcaacaaaac aatgcaaata
    12421 ctaatcaaca aaataataat tcaaatgtgc caacagctaa ctctaatgca gttcaagctg
    12481 tacttaactt ggcatattct aagcaaggtt gtccatatgt ttggggagca gaaggaccaa
    12541 acacttttga ctgttctgga tttacacaat atgtgtatag aaatgcagta ggaaagaata
    12601 taccaagaac atctaaagca caatctaaat atggacaaac tgtaagtaaa gcaaatttac
    12661 aaccaggaga cttagtattc ttcacaacta atggttctgg ttctgttagt catgttggaa
    12721 tatatgtagg tgggggtaat atgatacatt caccatcaac aggaaaaaca gttagtgtaa
    12781 ctagtataaa ttcatcatac tatacagcaa gatttgttac agcaaaaaga atattataat
    12841 cggtttgtaa tatgacaaat tgataaatac ataaatatat ataaacgctc tatattatat
    12901 ttaatttaat catggaaaca aaaaatgatt atattttaaa tgtactatag agcgtttttg
    12961 tatcacttta aatctaatca agattcaagt taatatgact gttaaatagg agccttttca
    13021 tatgatgatt atttgcgcaa tcccttgaca ggatagggca aaggtggtaa gctactaaca
    13081 gtacaaaaat acttttaatt ttagttcaga gaggctaaaa aaggaggacg aaagatgtta
    13141 aaatcaagaa atttaatcca gccagaagac ttttcaatag aagaaataga tgaaatatta
    13201 gaattagctc aaaaaataat tgacaatccg tcaaaatatt ctcgtatatg tgaaggaaaa
    13261 ctattagcta cattatttta tgaaccatca acaagaacaa gattaagctt tgaatctgct
    13321 atgaacagat taggaggacg tgtagtaggc ttttcagagc caaattcatc ctctgcatca
    13381 aaaggtgaaa ctctaggaga tacaatgagg atagtatctg gttatgttga tataatagct
    13441 atgagacatc ctcaatcagg tgcagcttca gaagcagcta gatatacgga agtgccattt
    13501 ataaatgcag gagacggcaa aaaccagcat ccaactcaaa cacttacaga cttacttact
    13561 ataaaatcat taaaaggaac tttagaaagc catacaatag gattatgtgg tgatttaaaa
    13621 tatggaagaa ctgtgcattc tttggttaag gctatggcaa gatataaaaa tacaaagttt
    13681 gtatttatag cgcctgaaga gttaaaaatg ccagattata taaaagaagc tataaaggga
    13741 catgcatatt atgaaactaa taatttggat gatgttatag gaagcttgga tgttttatat
    13801 atgactagag ttcaacaaga aagatttgaa gataaatcag agtatgaaag acttaaaaac
    13861 tattatattt taaataaagc taaattagaa aaggcatcta aagatatgtt agtaatgcat
    13921 ccattaccaa gagtaaatga aatagacata gatgtagata gtgatgatag agctgtatat
    13981 tttaaacaag ctaaatatgg aatgtatgtt agaatggctt taataataaa acttttaggt
    14041 ataaatgaag actaatagtt atcatataat agtaaaacaa aggagatttt gggatgtata
    14101 aaattctgga aaatatatat ataggcgaag atatgtatag aatgaaagta aaaggtaatt
    14161 ttgaaggtaa aatgggacaa ttctatatgt taagagcatg ggatacttat ccagtacttt
    14221 caagacctat aagtatacat gatatagatg aagaagggat aacttttctt tataaagtag
    14281 taggagaagg aactcaaatt ttgagtaacc taaaggtaaa tgataatata aaattagaag
    14341 gcccttatgg taatggatat gctaaggttg atggaaaggt agctctagta ggaggaggaa
    14401 tcggtgtagc tccactatat ttggttgcta aaaatataaa aaattgtgat gcatatcttg
    14461 ggtttagaga agatgttata ttagaagatg aatataaaca agtatgtaat aaagtctata
    14521 caacagtagg aaatactttt gtaacagata taattgatgt tgagaaatat gattatatat
    14581 taacatgtgg tccaactcca atgatggaaa aattagttaa gatggtagaa ggtactaaaa
    14641 cgagaattat ggtatctctt gaaaaccata tggcttgtgg agtaggtgcc tgtttagtat
    14701 gtacgtgtaa aactaatgga ggaaataaaa agacttgtaa agatggtcca gtgttctggg
    14761 gagaggacgt gatttttaat gggtaattta agtgtgaaat ttggaagtgt agaatttaaa
    14821 aatccagtaa taatggcgtc tggaactttt ggatttggaa aagaatataa tgagatttat
    14881 gatatacaaa aacttggtgg tataagtagc aagggtctta ctttaaataa aaaacctggt
    14941 aacaatggta tgagagttca tgagacatca tccggtatga tgaatagtgt tgggcttgaa
    15001 aaccctggag ttcaaggatt tatagactat gaattacctt tttttagtaa actagactta
    15061 gtcagaatag ctaatgttgg aggtgggaca ttagaagact acttattagg ggttcaaatg
    15121 ttaaatgaca agcctataga cattattgaa ttaaatatat cttgcccaaa tgtcaaagct
    15181 ggtggaatgg cttttggtat aaaaaatgaa gtggcaagag aagttgttcg tgaggtaaga
    15241 aacataacga aactgccttt agtaataaaa ttatcaccca atgcagaaga tattgtagga
    15301 atggcaaaag tttgtgaaga agaaggtgct gatggagttt cattagttaa tacttttaaa
    15361 gcaatggcaa ttgatataaa aaatagaaga ccagtatttg aaaatgtata tgctgggtta
    15421 tctggaccag ctataaaacc tatagctttg agaatggtac atgaagtgtg taaaaatgta
    15481 aatatacctg taatgggaat gggcggaata actaaagcca cagatgctat agagtttata
    15541 atggcaggag ctacttgtat ccaagttgga actgcaaatt ttatgaatcc tagaataggt
    15601 attgaaataa tagatggaat taatgaattt atggatagag aaggaataaa aagtttagac
    15661 gaaataagag gaattatata aggtagaata aatagtattt taaagataaa aaatatagat
    15721 taaataaaca ataattttat aacattaaca tggaggaaaa ataatatgag taaagtagat
    15781 gtagtggata tattaaagaa aagtgatgca ttgttggagg gacatttttt attatcttca
    15841 ggaaaacaca gtaatagata cgtacaatgt gcaaaagtat taagatttcc agaatatgct
    15901 gctgaggtat taagtacagt tgttgaacaa ataaaagact tagatataga cttagtagta
    15961 ggaccagcta tgggtggagt aatagtttct tatgagttag gaagacaatt aggaaaagaa
    16021 gctgtattta ctgagagaaa agacaataca atggagttaa gaagaggatt tgaagttaaa
    16081 aaaggagcaa agataataat tgctgaagac gttgtaacta ctggtaaatc aactatggag
    16141 acaaaaagag tattagaagc cttaggtgga gaagttgtag gtgttgcatg tatagcagat
    16201 agaactaatc atgatatagg tatgcctata tatagtgcta taaaacttga tattcaagtt
    16261 tatgaatctg atgagtgtcc tttatgtaag gaaggaaaat taccagttgt taagcctgga
    16321 agtagagagt tcaaggaatt agggatgtaa taaaaactta attatttata gtgttactta
    16381 aaaaatgtaa attttttaga gtaaaaattt gtaatataac atataactta aaaataaaaa
    16441 gcagttagcc ttataaatga aggttagctg tttttttgtt aaaaatatat ttacaaaata
    16501 agagatagta gcagtacaat ataagtataa ggtaaaagta ttatatatta gggaggggta
    16561 agtatgaaaa atcaattaaa tgaaaatcat aaaaaggttg tattttttgg agtaggtgct
    16621 gtaggagcta cttttgcaga acaatttttt aactctaaat atgattttaa aattctttgt
    16681 gataatgaaa gaaagaaaag atatttagaa gaaggattta taataaatgg aaaaaggtat
    16741 gattttgatt atgtaactaa agatgagtat aaacaagagg ctgattttat aattataggt
    16801 ctaaaatata ataatttaaa agaaaatata aaagaattag atggattagt tggaaaaaat
    16861 acagttataa tgtctctgct aaatggagtt gatagcgaag agataatagg agaaagattt
    16921 ggaattgaaa aaatggtata ttcatatgtt accaatatag atgcaaagaa aatcaataat
    16981 aatattatac acactactaa tgggataatt gtatttggta acaaagataa tagtgaagat
    17041 agaaaaacta atataataac cgaagtcttt gatgatgtaa atatagaata tactttatca
    17101 aaagatattc aacgagatat gtggtggaag tacatggtta atattggtgt aaatcaaact
    17161 tcagctatac ttggtgcacc ttatggagtt tttcagagtt ctgagcattt aagagaatta
    17221 gcaaaatctg caatgaggga agttgttgct atagcacaag caaaagacat atctcttaca
    17281 gaagatgatg tggaacattc attacataga atactagaac attcaaaaga aggaagaaca
    17341 tcaatgcttc aagatgtgga agctcataga cttacagaag tagatatgtt ttctaagaat
    17401 atctgcaaac ttggaaaaaa atataacata cctactccta taaatcagac tttcttttat
    17461 atgataaaag taattgaaag tagattttaa agggtctttg taagaaatat tgataattat
    17521 tgattttaaa ttttattaat gttatatact atttaagtta ctaaatattt ttaactcttc
    17581 aatgaaaata gttgctgctt ttgataaagt tatatctttt ggaaatatat atgagaaatg
    17641 tctgttgtag ctgcttccaa gctctatgac agacagctca ttgtttagaa caggtaagct
    17701 tgtcactaga ttagagacta ttgtaattcc taaattattt ctaacagatt ctttgacagc
    17761 ataattactt ccaaaaacca tcatactttt tggaataatt tctttaacac ttaaaaacat
    17821 atctaaataa tctctggttc cagaaccatc ctccctgact atccattttt ggttttgaag
    17881 tttatcaaaa ctaaaatctt ttaataaatg actcttgtat ggaagtgcta aaaccatctt
    17941 atcttcaaaa aaatattctt gaataaatga aggggaagag caagtgcctt caataagacc
    18001 aatgtctaaa atataatcct taacatgaga agatacgatt gatgtatttt ttataaaaac
    18061 ttctacatct atgtcaggat actttttaga aaataatgct agaaaatttg gtaaaatata
    18121 ctctccaata gttaaacttg caccaatctt taagtgacca gttatagcat ctgaaacttg
    18181 gcttacatca tgataagtaa tatttaaaag atttaatatt tctttagctc ttttgtacaa
    18241 gatttgtcca ctttctgtta taaaaatggt tttttgttta atagacctgt ttataagcac
    18301 aactttaaaa taattttcta gattttttat gtgtttactt acacttggtt gtgatagatt
    18361 taaatattcc ccagctttag taaagttttt gtattcaaca acagctacaa atgtttttaa
    18421 ttcttcaaac aattttttgt ctcctttacc taatgaaatt ttacattttt tatatacttt
    18481 ctacagataa ttatactata tataataacc attaaaaaca ttaatcatta cgatattata
    18541 tatttatttt acttatggtt attacaatta tatactattg ctatgaagaa aactatatta
    18601 attataaggt aggtatatta tgttaaagaa aaaaagcagt ttgacattaa aaactataag
    18661 ggaaatatta ccaggactgt ttgtatcagt attagtaggt tatattagta tatttatttc
    18721 tattttaatt cctaaggtag gggcagcatc aatttctata tttttaggta tgtttgtagg
    18781 aaacctattt ttaaatcaaa aggtatttca aaaaggttat aaattttcag agacagattt
    18841 gttatcatat tcaatagtac tattaggagc aacactcagt gtatctacct taatagactt
    18901 aaaagtttca ggaattttat ttataatatt gcaaatgaca ataacaataa tagctgcact
    18961 ttatataggt aaaaaactag gatttgaaga aaactttaga tttctaatgg caagtggaaa
    19021 tgcagtatgt ggttcttctg caataggagc aacagttcca gtggttaatg cgacagataa
    19081 agaaaaggga attgcagtaa ctattgtaaa tgttactggt atatttctta tgtttttact
    19141 tccaataata tctcaatttt tatatagcca tgaacttgta aaaacttcag caatgatagg
    19201 tggaactttg caatcaattg gtcaggttgt agcaagtgga gcaattgttg gagaaaatgt
    19261 aaaagatttg gctactattt ttaagatagt aagagtaata tttctagttg ttgttgtatt
    19321 agtatttgga catatgaaaa atcaatctaa tagggaaatt cttgaagaag aaaaggatga
    19381 gataaaaaag aaaaaagtga ctataccatg gtatgtaatt ggattcttta taacttgtgc
    19441 acttttttca atgaacatta taccaaaaga agtatctgtg ttgtgcaaag aaataagtaa
    19501 caaactagaa ataatagctt tagcagcaat tggattaaag gttaatgtaa aagatttagt
    19561 gaaacaaggg aaagaagttt ctttatatgg tttatttgta ggtatagtac aagttgtatc
    19621 agctgtagtt ttaataaaaa tatttatata
//
LOCUS       DAEHWO010000079        19332 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEHWO010000079 DAEHWO010000000
VERSION     DAEHWO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19332
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.079"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(216..1466)
                     /locus_tag="KNP54_003127"
     CDS             complement(216..1466)
                     /locus_tag="KNP54_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBF0893992.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1498..2439)
                     /locus_tag="KNP54_003128"
     CDS             complement(1498..2439)
                     /locus_tag="KNP54_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBF0893993.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2679..3755)
                     /locus_tag="KNP54_003129"
     CDS             complement(2679..3755)
                     /locus_tag="KNP54_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBF0893994.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4128..4643)
                     /locus_tag="KNP54_003130"
     CDS             complement(4128..4643)
                     /locus_tag="KNP54_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBF0893995.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5006..6076)
                     /gene="leuB"
                     /locus_tag="KNP54_003131"
     CDS             complement(5006..6076)
                     /gene="leuB"
                     /locus_tag="KNP54_003131"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBF0893996.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(6083..6574)
                     /gene="leuD"
                     /locus_tag="KNP54_003132"
     CDS             complement(6083..6574)
                     /gene="leuD"
                     /locus_tag="KNP54_003132"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBF0893997.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6589..7866)
                     /gene="leuC"
                     /locus_tag="KNP54_003133"
     CDS             complement(6589..7866)
                     /gene="leuC"
                     /locus_tag="KNP54_003133"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBF0893998.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7823..9565)
                     /gene="leuA"
                     /locus_tag="KNP54_003134"
     CDS             complement(7823..9565)
                     /gene="leuA"
                     /locus_tag="KNP54_003134"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBF0893999.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTTQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9689..9935)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10083..10529)
                     /locus_tag="KNP54_003135"
     CDS             complement(10083..10529)
                     /locus_tag="KNP54_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894000.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10550..11269)
                     /locus_tag="KNP54_003136"
     CDS             complement(10550..11269)
                     /locus_tag="KNP54_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBF0894001.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11387..12661)
                     /locus_tag="KNP54_003137"
     CDS             complement(11387..12661)
                     /locus_tag="KNP54_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBF0894002.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNVKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12861..14228)
                     /locus_tag="KNP54_003138"
     CDS             complement(12861..14228)
                     /locus_tag="KNP54_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0894003.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14478..14942)
                     /locus_tag="KNP54_003139"
     CDS             complement(14478..14942)
                     /locus_tag="KNP54_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBF0894004.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14947..15576)
                     /locus_tag="KNP54_003140"
     CDS             complement(14947..15576)
                     /locus_tag="KNP54_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBF0894005.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(15610..16497)
                     /locus_tag="KNP54_003141"
     CDS             complement(15610..16497)
                     /locus_tag="KNP54_003141"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBF0894006.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16526..17764)
                     /locus_tag="KNP54_003142"
     CDS             complement(16526..17764)
                     /locus_tag="KNP54_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894007.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(18148..19290)
                     /locus_tag="KNP54_003143"
     CDS             complement(18148..19290)
                     /locus_tag="KNP54_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBF0894008.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         6211 a         3544 c         1974 g         7603 t
ORIGIN      
        1 taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat tatagcatag
       61 aatatgacta tctatatcct aaaattatcc atttctaaaa aaaaggtaac tattattaag
      121 aatatcaact tatagaattt atattccaca tacgattttc aatcaaaaaa acaagggcta
      181 aaaagtgaat tgtgcacttt ttagcccttt attaattatt catttatttc atgtaagaat
      241 agaccacatc ttactttagg ttcaaaccat gttgacttag ctggcattat cttatttgca
      301 tctgctactc ttattaaatc ttcaatacta gtaggataca ttgcaaatgc tactttcata
      361 tcttcattaa ctcttttttc taattcttca agacctctaa ttccaccgat aaaatcaatt
      421 cttttatcta ctctaggatt atcaattcct aaaatagcat caataacata gtcttgtaat
      481 atagaaatgt ctaatgagtc aacagggtct tctatttcta ataaattttt atttgctttc
      541 attttatacc acttatcacc taggtacatt ccgaaagttc cttttttgtc aggtttatat
      601 ttttcttttc cttctatttc ttctagttca aaattttctt ttattttatt tataaattct
      661 tcctcgctta aaccatttaa gtctttgata accctattat aatccaaaac cattaaattc
      721 tcatctggtg caatcattgc tatgaagtaa ttaaattctt cttttccagt ataatttgga
      781 tttttagctc tcatttcttt ggctacattt tctgctgaag ctgtcctatg atgaccatct
      841 gcaatgtata gataatctaa tttttcaaat ttatctacta ggttatctat tatatcatca
      901 ttatcaatct tccatactgt atgctctatc ttgtcatctg ttatgaaatc atataaaggt
      961 tcattattat ccataaaatc attgattata tcatctatca ccctttgatg tttgtaagtt
     1021 acaagtatag ttcccgtatt agcatcacag tattttatgt gtttagttct atcaatttcc
     1081 ttttctggtc gagtgtactc atgttttttt attgttccat tcaagctttc atcaactgat
     1141 atacatgcta ctataccaac ttgagctcta ccatccatga tttgtttata tatatatata
     1201 cactctttgt catcttttac tagaatttct tgttttcgaa actcatctaa attttctcgc
     1261 gcttttaaat aaactttttc atcatataaa tctatatttt catctaaatc aatttctgat
     1321 ttatctatat gcaaaaatga atatggattc ccttctgcaa ttcttctagc ttctttacta
     1381 ttcataacat cgtaaggaag tgctgctact ttatctacta tatatttatt tggtctaatc
     1441 gccttaaatg gtttaatcgt tgccattact aatttcctcc taattataca aaatatttta
     1501 taatgctacc cctattagat tgttgaagtc aagaaagaaa tcttgaatca catttactat
     1561 ttcgtctcct attctttctt gagcttctac tgtagatgcc ccaatatgag gtgtaggaga
     1621 aactcttgga tgatttacta agtctaaatt taatgtaggt tcttgttcat aaacatctat
     1681 agcagctgct gataatttac cttcatctaa tgcttttagt aaatcttttt catcaactaa
     1741 accgcctctt gcacagttta ttaaataagc ccctttcttc atcttattta tttctttttc
     1801 agttattact gcccccttat tcttatcaaa tggtatgtgt aaagataaga aatctgcatt
     1861 ttctaaaact tcttccatat cacagaattt ataattgtta aagccttgcg cctcacccat
     1921 tatgtcagta tatataacat tcatacctaa taattctgct ctctttgcaa cttcttttgc
     1981 aattcttcca aaacctataa gtccaagtgt ctttccatta atttctgtac ctttatactt
     2041 tttcttctcc cattttccat ctctcatagt tacatttgca gtatttatga atcttgcaag
     2101 aacaaataat tgacctattg taagctctgc aacagatata ctgcttgcat ttggagtatt
     2161 cataactttt atgccattag cttgagcata tttaacatct atattatcca gacctactcc
     2221 acctcttact atcaacttca actttttacc ctctaatgct ttatctatta catctttagt
     2281 aactttagta gctgaacgta ctacaagtac atcaacatct ttaagtttat ctcctaaaac
     2341 atctttttca taaaactgct ctatcacatt aaaatctaac tctctcaatt ttctcgctgc
     2401 ttctttctct attccatcag taactaatat attatacata acaaactcct ccaattttta
     2461 ttcacttaat ttttccaatt tttatttttt aaagtatttt catcaataaa aaactttact
     2521 taatttaact ttctgtttat ataattttca aaatattttt ttattaaagt catatcaaat
     2581 ttttctattg tttgttaaaa atttaatatg taatttttat aaaatattat ttattatata
     2641 ttctaaattt atcttaaaac atacatattt ttacaatatt atttattaaa acctaatata
     2701 tcatcaatat tatctaataa ttcttgtaca tcttcgacag tatagtcacc catatgtgaa
     2761 attctaaaag ttttttcttt taaatctcca tagccatttg ctatttggaa tcctcgttct
     2821 tgtaattttg aatttaaatt tgatacacta ataccttgag tattttctat aacagtaagt
     2881 gtattggata agtgattttc attggtaaaa atttggaagt gttttttagc ccagtttcta
     2941 actaagtttg ccatgtcttc atgtctgttg aatctgttat ctaggccttc atctaatata
     3001 ttatctaatt ggaaatctaa agcgaacatg tgagaaagag atggtgttga agggtattgg
     3061 tagtttttct tgattaagta ttcatacatt gctaacaaat caagatatac tcctctaaaa
     3121 ggtacttgct tagctctatc gattgctttt tgagaaaatg tgcaaataga cattcctggt
     3181 ggtaatccca gtgctttttg tactgatgtt atacaaatat ctattccaat cttatcaacc
     3241 tcgactttta ttccaccggc tgaacttaca gtatctacac agtagattac atcctcatac
     3301 tttttaacaa cttctccaat ttcttctatt ggatttctta ttccagttga agtttcattg
     3361 tgagttacag ttattaaatc gtattctccg gtagaaagca ccttatcaac catttctggc
     3421 gttgttgcct ctcctaattc aactttaaat atatccgctg ggacattatt agccactgcc
     3481 attttgtacc atctatcacc aaaggatcca caggaaaata ctgctgcctt tttggatgta
     3541 caggaacgaa tggagccttc cattaaacca gttccggatg acgtggataa aagtatcgtg
     3601 ttgtttgtat agaatagttt ttgcatcttt tcacttatac tcttttggag catagatgca
     3661 tcttttcctc tatgtcctat cattggtgta gccatctttt gcaagacttc ttctttaaca
     3721 tcaataggac caggaataaa taatttctta ctcattataa ttcccccctt tttagtttgt
     3781 aatatggata gcgtttttac tgtccttatt tttaataact ataatatcaa gctgaattaa
     3841 ctatgtcaac ataaaattta ttttttatat ataatttatt ttatatattt tatgaaaaca
     3901 ttcattttct accttttcat aagtctgaat tttctgaatt attccctcaa aaaaaatata
     3961 ctttttatct atataaatta atttttttag tatgtaaatt ttacgctatt acgataaatc
     4021 tttttagtat aactaattta tttttatctt gtatttttat tgtatttttg aattttattt
     4081 tttctaaata taaaatttat gttttaaaat ataaaatttt tatttaatca aagttcaata
     4141 tattccactt tttctttcga ttcttcaaaa aaccattctt cattagaaaa atcaccttct
     4201 gcaatttgtc caataggcat tttcatatac tttccagttg ctgtcactgc tatatctcca
     4261 tttggtagaa ttatttctcc tgtaccttca aataattttc tgttttcttt agttattctt
     4321 ccaacaactt ttatagtagc atctgttggt actggtttct tatatttcaa ctctaaagat
     4381 actgttactc cccatatttg gtcatcattt atacttacag ctcttccaat agtctcatcc
     4441 aatattgcag cagacatacc tccatgaact ctcccaggat aactttgatg ccaatccttt
     4501 gtattacaaa ttgatacaag ctctccattt tcaagttcat aaaaatctgc tttaagtcct
     4561 agctcatttt gtgttccaca aactaaacaa gatttactac tattttgctt cttcaaaact
     4621 ttatactttg ccaaaaaatc catctcctaa ccgacattag tagtcgctta atattaaata
     4681 attctaaaat atattatata atattaataa aatccctgca aacttctaat aataaaaata
     4741 ggctacttca atatgataag tttaatttaa agtattattt tccaaaaaat aactttatca
     4801 aaatagaaac tcaaagtaga tataaacctc tttttcgtta ttaaaatagt aaaaatatat
     4861 ttgacttaat ataaaaaaga gtgtctcatt aactaataaa gtttattttg agacacccct
     4921 cataaaacaa attatactac aatagatttt tactaattct acaagttata tatttaaatt
     4981 atattattca aattaaacta taattctaaa tttcatttac tattaattcg cccatttccc
     5041 ttgttcctac aacatttccc acaccattat agatatcaat agttctataa cctttattga
     5101 gtacactttg tacagcatct tcaatacact tagcttcttc ttctaagtta aaactatgtc
     5161 ttaacatcat gcttacagat agaatagtcg caattggatt tacaatatct tttccagcta
     5221 tatcaggtgc acttccatgt attggttcat acataccaaa actatcttct ctaagtgatg
     5281 ctgatggtaa catacctata gaacccgtaa tcatagatgc ttcatcagat attatatctc
     5341 caaatatatt attagtcact attacatcaa attggctagg gtcttttaca acttgcatag
     5401 cagcattatc aacatacata tgtgacagtt ctacatcttc aaactcttta gctaagtctt
     5461 ccattatact tctccaaagt cttgaactct caagcacatt tgccttatct acacttataa
     5521 gttttttatt tctatttctg gctatttcaa aagctctctt accaattctt cttatttcat
     5581 tttcgttata tatttctaca tcataagcat tttcgatacc atcaatgatt tttcttccac
     5641 gttctccaaa ataaatgccc cctgttaatt cccttacaac aacaaaatca atgcctttct
     5701 caactatatc cgttctaagt ggtgaagctt cttttatact ttcatacatt gtagctggtc
     5761 ttaaatttgc aaataaaccc aatgactctc ttaattttaa aagaccagac tctggtcttt
     5821 tatctccctt acatttatcc cactttggtc ctccaacagc accaagcaat acagcttcgt
     5881 tttttcgaca agtttcaaca gttttattag gtagaggttc tccagtttca tcaatcgcgc
     5941 atcctccagc taatacatat tcacaatcga atctatgatt aaatttacaa caaattttat
     6001 ttagaacctt tataccttca tctataattt ccggtccaac accatcacct tttatgactg
     6061 ctatattaca attcatactt cactaccccc tatttgcttt tattgagtta attaagcctt
     6121 catttaatat aatattttgc ataaactcag gaaatggttc tgctttatat tcttttcctt
     6181 ttgttatatt ttttatcaca cctgtagaaa aatctacttc tatattatcc ccttcatcta
     6241 tgttattggc agcttcttca cattcaagta taggaagccc tatatttata gagtttctaa
     6301 aaaatattct agcaaaagta gaagcaatca cacaggatac tccactttct tttattacaa
     6361 ttggtgcatg ttctcttgat gaaccacaac caaagttttt agttgcaact ataatatctc
     6421 ctttttttac cttagaaata aatttatcat caatatcctc catacaatgc gttgctagtt
     6481 ctttataatc agctatattt aaatatctag ctggtattat tacatctgta tctatattgt
     6541 caccgaattt aaaaacactt ccattggcaa tcataaattt tacctccctt aaattatttc
     6601 tgatggtttt gatatttttc cagttatagc tgatgctgct gctacagctg ggcttgcaag
     6661 atacacctct gaatcaacat gccccattct tcctacgaaa ttcctatttg ttgttgaaat
     6721 ggatttttct cctgctgcaa gtatacccat atgtccccct agacatggac cacaagttgg
     6781 tgtagaaact gctgctcctg cctctataaa agtggtaata tacccttttt ctatagcttc
     6841 aagatatact ttttgagttc caggaaatat cataactcta actccatctg ctactttttt
     6901 gcctttcatt atctcagcta ctacttcaag gtctgatatt cttccatttg tacaagagcc
     6961 tattacaact tggtctatct ttatatcctt atctatctca tctactgttc tagtattttc
     7021 aggaagatga ggaaaggcta ctgtttcttt tagttcagct aaatctattt cgtatacttc
     7081 atcatagact gcatcttcat ctgcttcata tatatttaca tcttttgtca tagttgaaca
     7141 cttatgtgaa tttatatatt ccatagtctt atcgtctact ggaaaaattc cattttttgc
     7201 tcctgcttct attgccatat tacaaatagt aaatctatca tccatagata agtattctac
     7261 tccatctcca caaaattcca ttgacttgta aagtgctcca tcaacaccta tctcccctat
     7321 tatatgaagt attatatctt taccacttat ccatttattt ggtttattct tcaaaacaaa
     7381 ttttattgct ccaggaacct taaaccaaca ttttcctgta gccatacctg ctcccatatc
     7441 agttgaacct acaccagtag aaaatgctcc taatgctcca tatgtgcaag tatgagagtc
     7501 agcacctata attacatctc cagcagttac tatacctttt tcaggaagaa gaacatgctc
     7561 tattcccata tctcctacat caaaaaaatt tacaactcct tttgattttg cgaaacttct
     7621 tgtaaattta cattgttctg cactctttat atctttatta ggtgtaaagt ggtctaaaac
     7681 catcactact ttagtcttat cataaacatc ttcaattcct aatttttcaa attctctaat
     7741 ggctactggt gatgttatat cattacctaa aactacatct aaatctgctt cgattaattg
     7801 ccctttctta acttcattta atttagcatg tttggctaat attttctgcg tcatagtcat
     7861 ccccattttt tatttcctcc tcaatataac ttttatttat tgcattcata agtgcattaa
     7921 tagctgctgt atttatgttt tccgatatac ttacaccaaa atagacttca ttattgtgct
     7981 ctattcctac ataagctacc cctcttgaat gtgacccttc ctctaatgca tgttcccagt
     8041 aatatctaaa tttataatct ttcatgccac attgctttag tgcattatta aatgaatcta
     8101 caggtccatt tcctatacca acaatccttt gttcatttcc catataactt attcttgcag
     8161 tcatctcaat catgttagta tcattagaat catcattttc atagtttaat tcatccattg
     8221 attttatttt atacttctta actttataag ggctctcaac ttcaatatat tctttcttaa
     8281 acaaattaaa tattgcttca ctactaagtt cttccccaat tctatcagat tccattttga
     8341 ctacatttcc aaaatcagaa tgcatattct taggtatcat aaatccataa tctgtttcca
     8401 ttatataaac agctcctcct tttccagatt ggctatttat ccttataatt tctttgtatt
     8461 ctcttccaat atcatgaggg tctattggta aatatggaac ttcccagtaa tcattatctc
     8521 tgtttttcat tgctatcatg ccttttctaa tagcatcttg atgtgaacct gaaaaagcac
     8581 aatgtacaag attacctgca tatggatgtc tatcatgtac cataagtttt gtacaatctt
     8641 catatatacc tattatctta tctatattgc taaaatctag ctctgggtct attccttgtg
     8701 tataaagatt aagtcccaca tttactatat ccatattccc agttctttca ccatttccaa
     8761 atagtgttcc ttcaagtcta tcggcaccag ccaataatcc aagttcactt gcagccgtac
     8821 aagttcctct atcattgtga gtatgcaaac ttagtataat agaatcccta caacttatat
     8881 ttttacaaaa ccattctatt tggtctgcat atacgtttgg tgttgccatt tcaactgttg
     8941 atggaagatt tattattact tttttttgag tagttggttt ccaaacatct atcactgcct
     9001 cacatatttc aagtgcataa tccatctctg ttcctgtaaa actctctggt gaatattcaa
     9061 aagtaaattc tgtttctgga tattttttta cttcttcatt aaataatttt gctccttcaa
     9121 ctgctatatc tattatttct tgtttactca tattaaaaac cacatctctt tgaagaacag
     9181 atgtagagtt atataaatgt ataattgctt ttttacatcc ccttattgat tcaaatgttt
     9241 tttctataag atgagcccta gattgtgtaa gtacttgtat agttacatca tctggaatca
     9301 tattctcatc tattaatttt cttaaaaatg tatactctgt atttgatgct gatggaaatc
     9361 ctacctctat ttctttaaat cctgtatcaa taagcatttt gaacattctg actttttcat
     9421 ttacactcat aggtgttggc agtgactgat ttccgtctct taaatcgaca ctacaccaaa
     9481 ttggagcctt aaatatttca ttatctggcc atttacgatt tactatttgc attttatcat
     9541 attttttata ctttccacac ttcatgttat ttcccccttt ttctgttttt tgtattcagt
     9601 atacctcata tcgacgcaat cctgcacaat tcataaggat aaatgtcaat tttatcatta
     9661 gaataaaaaa aacctcatct ctaataaaat tagagacgag gttttgctcg cggtaccact
     9721 ctatttagct ttctaaaaag ctcccttagt aatagccaat acaataatta taatgactat
     9781 atttcctata acgtggaatt actccgatta ttctaagatt taaatcttag aaaacagctc
     9841 ctagacaagt tcagaactat caactactaa atcacaccat cctttagctc tctgaaagtt
     9901 tcattgttct tactacttct attcatcact tttttaatca tttaaatttt ctaaatattt
     9961 tgatttaata gttattatat acacattaaa atgtattgtc aacacaaaaa ataattatct
    10021 caatttttta tttttgataa gcaattctat aaaacatgct aactattgaa aacagtatga
    10081 tattatgcct taaacttttt catcttttca tctatgatat tcaataattt tttttcatct
    10141 tccaaactca atgcccttaa tctaatttta taattagatt cgtcagtgta tatatttaat
    10201 atatttttta ctacttctat tttttctatt atcttataat taaacttttg actttgttta
    10261 gattttatac tgaatataca ttgattattt attaatattg aatgattatc gagagtaata
    10321 tatacttttc cctcatattt atttgaaaaa tcacgacctt gtttaaatag aaaaactgct
    10381 gttattatac ataaaatata taatattgtc gttgaatata taaaaattgt agctaaaatt
    10441 ataagtgcta aaaccatata tatagtcatt ccttttttaa aataaccatt gtcataataa
    10501 ttcatataga taaacttatt tttactcaaa ttttttcact tccaagattc taaaaattta
    10561 tatcaaaaaa ttctataatt tcatcttcat gataatttat gactaattca tctggaaaat
    10621 ctactgcttc taaaactttt tctgcatttt caaattctcc tatagaataa catatatgag
    10681 agtcagtacc aagaattact cttgcaccat atgttttaca caatgtcaac atatgactta
    10741 cattttccca agtacccgtt ctatgagagt ttgaacttaa tgatgaatta tttatttcta
    10801 aaaggatatt tttatcttta gcttttttta ctataggttc ataatctaaa ggatacctac
    10861 tgtcatctgg atgtccaatt atttttacct taggtttatc cataactttt aaaatagcat
    10921 ttgtattttc ttcttttgta ccagaagcta tacaaggtct atgcaaactt gcgattatat
    10981 aatccaaatg ttgcaacata tcttcttgaa catctaaatt accattataa tccattatat
    11041 ttccttctat tcctctaaga atctttacgc cttgcacttc acgtggaagc aaatgcaaat
    11101 tataaaaata gaatggatgt ggtcctcctg gcatattagg tccatggtct gatattccta
    11161 agtattttat attcttctta ctcgcctctt cgacattttc cttgaaagta ctatgtgcat
    11221 gtccacttat tagagtgtga caatgtacat ccataataga ctttttcatt aaatttcctc
    11281 ctaatatttt acataaattc gtgaaaatag ctaaagggct atttcaaaac taaagctgtc
    11341 ataatagaca gtgtaacgtt ttaaaacagc cccattttca attattttac acttctaaat
    11401 ctttaaattt atctttaaat aattctccaa tacttcctaa agattcctct acttctaggt
    11461 attctgttat atcctcttct ggctctctag ttgcttcttt tattgaaacc aacattctct
    11521 tagtctttgg tttaaaatca agaatcttaa ctttaacctc atctccaata ttaacaacat
    11581 tagtaacttt agccactcta gtatcactca attcagatat tggtaaatac gcatctacac
    11641 cttctttaat ttgaacaaaa gccccttttt ctattattct aagaacttta acattgacaa
    11701 catcatcaat ttgtacttct tttgctatta aatcccaagg gtcattattt atgtctttta
    11761 atgccaaggc aattttttta gtctctttat ttacatccaa cacataaact tctacttctt
    11821 gtccctctga aacaacatct tcaacacttt caactcttgt ccaagctaaa ttatttatat
    11881 gtgctaatcc ttcaatccca ccaatatcca caaatgcacc ataaggcatt atctttgtca
    11941 ccttaccatc tcttttttgt ccaacttcaa gagaattaaa taagtcttct ttagctgctt
    12001 tgatacgagc tttttcttct tctctttctt gcttaattct tgctctttca gcttcttttt
    12061 ctgccttaat ttgagctctt ctttcttctc tctctttatt tatacgctct tgtaatacat
    12121 ctctatgaga tgctacaagt ctattttttc taacatccaa ttcttttata taaacttcta
    12181 agttaagacc aacaaattta gatgtatctg taataaattt tgtatcaagt tgagaaattg
    12241 gtataaaaaa tgtatatgta ttgtaattag caaatacacc tttatctata ttcttttcaa
    12301 catttacagt tattattcta tgttcatcat aagccttttg taactcggca aaatcatttc
    12361 ttttgtcaag ttgtaattta gataaagtta ttgtaccatc tttttgagat acttttgtta
    12421 ttacagcagt tatttcatca cctatgtggt atatatcttc tatatattga tttttttcta
    12481 tgttcaattc acttataggt attattccat caaacccata gtctaatcct aattgtactt
    12541 catcatttct cactgcagtt atttttccag ttgtcaattc tccaactttc actttgctga
    12601 atacttgttc ttgctggtca agtaattctt gcattgttaa atcattttcc attataaaca
    12661 tcctttcctc ttattgatta tcatatctgt aaatattata ccattaatat tgcaaatact
    12721 tacatttttc ttactataat ttttaaaata aattcaactt catatattta tacattatag
    12781 aaaatatctt attaaattaa aatacaaatt ctaattttta tctaataaaa tattttcata
    12841 aaaaatttat attgtatatc ttattctttt attgctttag gttttgatag aaaacattta
    12901 taaaatataa agaaagaaat tgctgttata gtagcggctg ttatatctgc aactggctct
    12961 gctaaaatta ctgcaaaaag tttttcatta aagaatgttg gaagtataaa tattaaaggt
    13021 attaaaagta caatctttct aagtagagct aaaaccaaag atattgttgc ttttccaagt
    13081 gctaaaaatg tctgttgaca agctatttga atcccaaaca taaaagcacc agcaaaatat
    13141 atttttatac tccaactagt catactaagt aactgcggat tcttattaaa tatactaaca
    13201 aaaaatgcag gaaatatcat taataaaagc cataaaatag tagaatatgt aaaacatgac
    13261 aataaacaca acttaaatgt cttttttact ctatcaagtt gacctgaacc ataattataa
    13321 cttattattg gttgtgctcc ttgtgtaacc cccatattag gaagcataag aatttgcatt
    13381 atactgctca ttatggccat tgaacctact gctaaatctc ctccatacat ttgtaattta
    13441 ctatttaagg ctataagtac taaactttct gtagattgca ttataaatgg agagattccc
    13501 aagccaagca ctggtaagat gatacttgct tttggtatca tatacttctt ttttatttta
    13561 agtatacttt tctttccaaa gagaaacata agtacccaaa tagcagaaac gccttgtgca
    13621 attatagtag ctaatgcagc tccttttaca cccatattaa agccaaatat aaaaatcggg
    13681 tcaagtatta tgtttattaa agcacctata gcaactgtca tcattccagt tgtagcaaac
    13741 ccttgggtat ttataaaagt attcataccc attgaaatct gaacaaacac tgtacctatt
    13801 aaataaatat ttaaatagtc cattgaatat ccaattgtag attcacttgc tccaaacatc
    13861 caaagtaaag gctcttttcc aatcttaaaa cctatagtca aaagtattgc taaaatcacc
    13921 aatacagaaa aactgttact cattattttc tctgcctcat cattgttttg ctcacccatt
    13981 tttatagcag ctaatggacc tcctcccata ccgattaaat aactacatgc agttattata
    14041 attattattg gaaatgccac tccaacacca gccatagcaa cttctccatt ttccattcta
    14101 ccaataaaaa tcctatcgac tatgttgtat aaaacattta caatttgtgc gataatagca
    14161 ggtgtagcaa gtttaaataa taatttaccc acactttcac tacctaagtt agtgtttgaa
    14221 ttttccattt taaaacctcc tcaatccaat aattaaaatg tatcactaaa attttattct
    14281 atataaaaat ttcattttat tagcagacaa atttagagta ctttccctac aagtaatact
    14341 atactatatt tcttttgcca tagtaaacat tttagaacta actgaagtta aatactttat
    14401 ctcatttttt atttattatt aaaaattttt cacatatact cataaaaaaa ctatccaagt
    14461 atattactta gatagtttta tattatatgt aaagaaagag ctgaaactat aacccctgat
    14521 aacaaattgc caagaaatac tcccataaaa gcatctttta ttctcatttt taatatggaa
    14581 gctatagcag atgcagtcca tgttcctgta gttggcagtg gtatacctac aaatagtatt
    14641 ataccaatta tcgaaacact ttttaatttc ttcattcttg agtttatttt tctatcaatt
    14701 acatcagcaa tccctttaaa tagtttcttc cctcttaaaa attgtaatac atgtctgaat
    14761 gtcaatatca agggaatcga taccaatgta gaacctatta cactaaatac ataaacccat
    14821 ataggattta agcccattgc aatacctata ggaatggctc ccctcaattc tgttacagga
    14881 accatagata aaattaatat gtgtaaatat cccaaactat tccctcctat tctaagtgac
    14941 attaagttat gaatttattt gctctataac ctcaccatcc tttttactaa ctaaaaatgc
    15001 atttttagtc aatgaaagca ttggtaaatc actcttagag tctgaatatg catatgaatt
    15061 ttcataatca atctctatcc caagtttacc taatacagcc tttattcttt ttactttttc
    15121 aattccctta cagttttctc caatgaattg atttttatat cttgaatttt cataaaaaaa
    15181 ctccgtgcct ataacctcgt ctgcaagacc ataatactta aaatatttca tatatgcata
    15241 tggagatgca gttatcataa ttataacatt atcttcttct ttatttttgt aaataacctt
    15301 tttcatagat tcgttaattt ttttcattat gcaatcatca aaaaactttt ttaaatcttc
    15361 ttcactaaaa tctactattg gataaaagat tgcctctttt gccttcttca agggtatcat
    15421 tctaattaaa tacataaata gaataaaaat aatgtatggc aactttataa tagttttaaa
    15481 ggttttattt tttaaagagt aaataaaaaa atctatcatg ctatcagtat ttataacagt
    15541 ataatctaca tcaagtaata atacactttt tttcataagt atttccccat cctatcacta
    15601 aaaatatcac taaaaaatca atattattaa acatgtaatt atccataaga ttacgtttat
    15661 ttttaaagca ttatctttta ggacaatatc agtaggatta ttttcatttg tagtgttaat
    15721 tatataatta tatctaagta caccataaac tacaaatatt gttgtaaata tcatatgtgg
    15781 cttttctgga ttacttgtag aatacaatgc ataacataca attgtagaac ttaatataac
    15841 tatcatcatt tgatttagat tttctatgtc ataatcttcc aatatttttc tatgttcaac
    15901 tgcatcatct cttagagttt ctatttcttt tttacgtttt ccaagagcta agtacagaga
    15961 taagaaaaat gtacataaaa ttatccaatt tgataaacta acacttatgg ctacacatcc
    16021 tgcataaacc ctaagtataa aaccaagaga tattgaaaac acatctaata gtattatatt
    16081 ctttagttta agagaatata atatattgtt tatcaaatag agactgagaa ttatagaaag
    16141 attaaaacta acaactgttg ataaacagac tgaaattaac gctaatacta caaatagtat
    16201 attagcactt tttttgctta ttcttccact tgccactggt ctattacatt ttttaggatg
    16261 ttttttatct ttatccatgt ctatagcatc attcagtgca tatactgatg atgacattag
    16321 gcaaaaacac acaaacgcaa taaacgtatt taaaaataaa tttatattta gtatgttgtt
    16381 tgaaaaaatt atagctgaaa atacaaagaa attctttata tattgcttta ttctcattaa
    16441 ctttatataa tctgaaattt tagtaagaag ccttatactt gtattggtct gtttcataaa
    16501 cttactaccc tttcaatatt attttttaaa caggatatga ttttatccct atgtttaaaa
    16561 tttctataaa tccattgaca ttactgatta ctatagtaac caataacagc gatagaaata
    16621 tattatacat attcttttca ttttttctaa gggctttcgt aaagtaagcc aataaaatta
    16681 taactgcaaa actaaaattt atagccataa tacttgaatt gactagatta tatcctacta
    16741 taccatgtaa agttagattg aatataatta ttcccataca tagcttagga actctttttt
    16801 ctgaattttc aataactgat aaaacacaaa aacataaagc taataatgta agaattactg
    16861 gtattgtagc aacttctcca ttttgcaaaa ataacccttt tttaatactt gctccaggaa
    16921 aataaaaaac cgaatacaat aatctctcta taatcattgc aatcttttcc aaaattggtt
    16981 ctccacttat aaatttcgta tcatactgta ttacatttcc aaggttcata aaactctcat
    17041 aagacttcgt tgaaactaca caaatatatg ccattaggat aaatgtaatt aaatgtttta
    17101 acatttttcc tatttttaat ttaaactcaa atatcatatt aaaaaaatac aaatatatat
    17161 tactaatagt tattccaaat agaggaatag ctgctaattc taccaaataa gaattttttc
    17221 ctttcatctt atttgcaata actatgaaaa atattaatga aaattggcta tatataaatc
    17281 tctctacatt taaagtcata aataactgtg gaaaagaaaa tatcattatc atagtaagta
    17341 aaattaaagt taatctctgc atttttatct ttttaatatg attaaagact aaagttattg
    17401 acatagcact agttattatt tgtagacaaa ttagtccaaa cccataggca ctattaaaat
    17461 ctgttgtccc aggatttgct attgaagtac aaaataggta tattggatat gcaaaaattg
    17521 atataattgc tgaaaacaat atatgcttac tattgtcttg acttatagca aatacattta
    17581 aattgaataa aactcctgta tctgtatcta acaatacatc ataagtattg tttaaatcat
    17641 aaaatatagt agtcttagaa aaaaatatct tagttattat taagtaagtt attacaacta
    17701 atataaacaa aaacatctcg tttttatatt ttaatatttt actcatcaat atatcaccat
    17761 ccattcatta tataggattt gctgacacct acaatttatt ccttatattt aatagccatc
    17821 ttcataatgt tcttacttgt tttattgtaa ttgaataact ctttatttac aaccacaata
    17881 tttactttat tgatgttata atcagtcaag tattgtttat ataacataga ttagtgttgt
    17941 ataaaatgag aatttgtaag caatattaat gtaaaatatt tgaaaaactt tatataaaaa
    18001 tatacaatgt tacttatgga attaaactat aacaaattaa agcataattt aaggagacaa
    18061 aattataatc tgtctcctta aatattaaaa ctatatttta aaacattact aaatactata
    18121 caaatttcaa atatagtata aaattaatta gactttaaca ctattagctc catcttcttc
    18181 ccatttttta atttctttta atctatctat tataggtaaa tgctgagtac attcaacttc
    18241 acattttcca caagatatac attctttagc ttttgcctta ctattcattg tgtaattcca
    18301 atgtcctaag ccataaacta actttgtcat ttcttcatca ctctttttaa acatctgctt
    18361 ttcattataa aaaagcatat aggctggggt attaatacct tttggacata ctttacaata
    18421 accacaacct gtacatattt cgttcatatt cttatttaat ctagtctcaa tatcatgtat
    18481 atcctcatct gaataaattc tattttcgtc tgcaatttta catgcatcat ctatatcttg
    18541 ttttttatta aaccctatca aagatatact tatttgtgaa attcctatgt tgaatcttaa
    18601 agctgattct atagtacttt cgccatcttt tgatagaaaa gaaagttctt tattatactt
    18661 tggaatagtt ccaccactta atggattcat tgccacaaca ccatatccat tatcaacagc
    18721 atatttggca ccttttagcc tatatggaaa gtttaatata tttattccca tagttacacc
    18781 ttcaaactta ttttcactta gaatatctat aacctcatct cctggttgat gagatgaaaa
    18841 tactatatgg tctatcaatc cttcttcttt acatttcaat aatccttcat attgacctcc
    18901 aggtctcatt gctagttcgt aatgttccat ctttctaata ttccaaacat gataaaaatt
    18961 tattttagat acgcctaatc gttctattga tttttttaca gcctctatag ctttttctga
    19021 tgtatcacat gcttttggct tttctttagt tgatacataa aaatcggtct taccttcctt
    19081 tatcatttgt ctaaaggcta gtccaaatat atcttcactt ctgtcatcac aataccctgg
    19141 tgctgtatca aagtaattaa tacctttttc atacgcatat ttgactaaat cagcattttc
    19201 ttgattactt ttttctaaat caaaccttaa tcctccatag ccaactactg aaaccatttt
    19261 ccctgtcttt ccatattcaa cgtatctcat tgtaaattcc tccttagata tattaagact
    19321 taatttcttt at
//
LOCUS       DAEHWO010000080        19256 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEHWO010000080 DAEHWO010000000
VERSION     DAEHWO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19256
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.080"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            335..913
                     /locus_tag="KNP54_003144"
     CDS             335..913
                     /locus_tag="KNP54_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBF0894009.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            952..1530
                     /locus_tag="KNP54_003145"
     CDS             952..1530
                     /locus_tag="KNP54_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBF0894010.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1616..2245
                     /locus_tag="KNP54_003146"
     CDS             1616..2245
                     /locus_tag="KNP54_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBF0894011.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            2235..4994
                     /locus_tag="KNP54_003147"
     CDS             2235..4994
                     /locus_tag="KNP54_003147"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBF0894012.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     LKKTA"
     gene            5081..6643
                     /locus_tag="KNP54_003148"
     CDS             5081..6643
                     /locus_tag="KNP54_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBF0894013.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6644..7780
                     /locus_tag="KNP54_003149"
     CDS             6644..7780
                     /locus_tag="KNP54_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBF0894014.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7844..8920
                     /locus_tag="KNP54_003150"
     CDS             7844..8920
                     /locus_tag="KNP54_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBF0894015.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDFMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8898..10136
                     /locus_tag="KNP54_003151"
     CDS             8898..10136
                     /locus_tag="KNP54_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBF0894016.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            10190..11278
                     /locus_tag="KNP54_003152"
     CDS             10190..11278
                     /locus_tag="KNP54_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBF0894017.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11306..12097
                     /locus_tag="KNP54_003153"
     CDS             11306..12097
                     /locus_tag="KNP54_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBF0894018.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKCDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(12212..12766)
                     /locus_tag="KNP54_003154"
     CDS             complement(12212..12766)
                     /locus_tag="KNP54_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBF0894019.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12962..14164
                     /locus_tag="KNP54_003155"
     CDS             12962..14164
                     /locus_tag="KNP54_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBF0894020.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            14221..15201
                     /locus_tag="KNP54_003156"
     CDS             14221..15201
                     /locus_tag="KNP54_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBF0894021.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLSEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            15444..16397
                     /locus_tag="KNP54_003157"
     CDS             15444..16397
                     /locus_tag="KNP54_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBF0894022.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            16387..17343
                     /locus_tag="KNP54_003158"
     CDS             16387..17343
                     /locus_tag="KNP54_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBF0894023.1"
                     /translation="MKLSLNQKIYFVSILLFISMALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            17340..18095
                     /locus_tag="KNP54_003159"
     CDS             17340..18095
                     /locus_tag="KNP54_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0894024.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            18187..19152
                     /locus_tag="KNP54_003160"
     CDS             18187..19152
                     /locus_tag="KNP54_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0894025.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAETLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         7604 a         1961 c         3452 g         6239 t
ORIGIN      
        1 ggtagtagtg gcgaagacac cgtccgaagt agcttggctt tgtaaccacc tctgttgtac
       61 tgtttaagta taaataagtg tgttagccac caagaatccc cttgctttag ctatggggag
      121 tgtgtcaaat attaaacata gcttttatac atttaataag gtatgtaaaa tctatgtaaa
      181 aagtaagaaa tataaacatt tttttaatta tattttaaaa atatcaagca agttttcttc
      241 acaaatgaat aaaaaatgtt ataatatgat taaagaaaaa gataaataat tagcaagatt
      301 tgtttagcta aaattaacaa gggagcgata aattatgggt ataacattat caaaaggcca
      361 aaaggttgat ttaactaaag gaaatccagg tcttaaaaat attttagtag gtttaggatg
      421 ggatactaac aagtatgatg gtggatttga ctttgattta gatacagcag catttttaac
      481 aggagcaagt ggaagtgtta ctaatgatgg agattttgta ttttacaaca atttaaaaca
      541 tacatctgga gcagttgagc atctaggaga taacagaact ggcgaaggtg atggagatga
      601 tgaacaaata gttgttgatt tatctaagat tcctggagaa ataagcaaga tttcttttac
      661 tgttacaatt catgatgcaa cagaaagaag acaaaatttt ggacaagtaa gtaattctta
      721 tataagaata gtagataaag acacaaatga agagttaata aagtatgaat taggagaaga
      781 ttttagtata gaaacagcta tagtagtagc tgaaatatat aagcacaatg gagaatggaa
      841 gtttaatgca ctaggttctg gctttgaagg tggtcttgct gcattatgtg gaaactttgg
      901 aataaactta taatttcaac tataacaata aactaaaggg ggatattttc catggctata
      961 gtattaaaaa aaggacaaaa aatcgattta actaagggaa atccaggtct taaaaatata
     1021 aaacttggac taggatggga tacaaattca tttgatagtg gctatgatta tgatttagat
     1081 gtaagtgttt tcatggttgg agaatctcaa agagttgaaa aagatgaaga ttttatattc
     1141 tacaataact taaaacatcc atctggagca gttgaacact taggtgataa tagaactggt
     1201 gaaggtgatg gagatgatga ggaaatatta gtgaatttag agacaatgcc aaagcatata
     1261 caaaagatag ctgtaacagt tacaatatat gaggctgctg aaagaagaca aaattttgga
     1321 caagtaagta actcatatat aagagtatta aattctgaaa atgatgaaga aatattaaga
     1381 tatgacttag gtgaagaatt tagtatagaa actgcaatta cagtatgtga gatatataag
     1441 tataatggag aatggaagtt tagtgcagtt ggagcaggat ttgaaggtgg cttagaagca
     1501 ctttgtagaa actatggctt aaatgtttaa tttaagcaat ataatatatt aaatataaat
     1561 aacctataca aataatgtat aggttatatt atataaaatt ttgtggaggt ttagtatgtc
     1621 gattaattta tcaaaaggtg ataaaataga tttaaaaaaa tctaacccag gactgagtaa
     1681 catacttgta ggtctaggat gggaccctgt gcaacaatct ggtggaggtt tttttaaatc
     1741 gttatttggt ggaggacaag ctgatataga ttgtgatgca tctgtattta tgcttaatca
     1801 agaaggtaaa ttaagtggaa taaaagattt aatttatttt ggaaatctaa aaagtgcctg
     1861 taaatcagtt ttgcatacag gagacaatct aactggtgag ggtacaggtg atgatgaaca
     1921 aatcctagtt aatttggata aagttccatc aaatattcat aaattattgt ttgtagtaaa
     1981 tatatacaat tgtgtagata gaaaacaaca ctttggaatg atagaaaatg cctatataag
     2041 agttgaagac caaggtaata agaaagagat agcaaaatac aatctatctg ataattattc
     2101 tgaaaaaact actcttatag taggagctat atatagaaaa gatggaagtt ggcaatttaa
     2161 agcaattggt gaaggaacaa aagatgcggg tcttaaagaa gtaatgcaaa atttagacag
     2221 gattgagtgt gcatatggaa tttaataatg atatcaaata ttataatgta gataaagaag
     2281 aagttacaaa agacttatct gttaatcctg aaaaaggttt atcagaatca gaagtcaaga
     2341 ctagaagaga aaaatatggt ttgaatgaat ttactccaaa agaagagggt agtttttggg
     2401 atgatttaaa ggaaagttta agtgaaccaa tgatagttat cttgattatt gcagcagtag
     2461 taagtgcagt aattggggaa actcatgatg caatagggat tgtaggtgct atagcaatag
     2521 gtatagcaat aggtatgatt acagaaggtc gttctaagaa agcagcagag gctctttcta
     2581 agttgactga aaacatagaa gtaaaagtat tgagagatgg ggaagtacat caaatttcta
     2641 agagtgaatt ggtaccaggt gatatagtat atattgaaac tggtgacatg gtacctgctg
     2701 atggtagact tatagaaagt ataaacctta aaattagaga agatatgtta acaggagaat
     2761 ctgatgacgt atctaaaaag tgtgatgtag tagtttctat ggaagagata gaatctaaag
     2821 gagcagtagt agtacaggag ccaatacctg caaaacagat aaatatggtg tttggtggca
     2881 cacttgtagc ttatggtaga ggagctctag ttgtaacttc aattggagat aatagtgaaa
     2941 tgggtaaaat tgctcaaaac ttatcagaaa cagatgagca aactccactt cagataaaac
     3001 ttggaaattt aggtggtttg atagccaaag tttctagtgc agtagcagga ttactattta
     3061 tatttatggt tttccaaatg ataagtaaga atgtattaaa tgtagatatg tctggaatat
     3121 taccgttttt agaatcaata gacccagtta aaacagcatt tacagtatgt gttgcgttga
     3181 tagttgcagc agtgccagaa ggtcttccaa ctatgataaa tatgacactt gcaataacaa
     3241 tgcaaaaaat ggctaaaata aatgcattgg ttactaaaaa agaagcttgt gaaacgatag
     3301 gttctgtttc tgtaatatgt tcagataaaa ctggtacatt aactgaaaat agaatgactg
     3361 tagaagttgc atatgttgat ggcagatata ttgaaagttc agaagaggaa ataaatagtt
     3421 attttgaaga aaactgtatg ataaactcta cagctgatgt agagcacaat gatggtgata
     3481 ttaagtattt aggaagtgct actgaatgtg cattgctttt atattacaaa aacgtagatt
     3541 atagacaagt tagaaaaaat tctaatatag tagctcaaaa tccttttact tcagattcaa
     3601 agagaatgac ttctgttata ggtcaagata atcatcatgt actattatca aaaggagcac
     3661 cagaagtctt acttgaatta tgttcacata ttcaaagagg aaaagacata gttccattaa
     3721 ctgaaaatat aaaacatgag attttagaag aaataaagaa attgcaaata aaatcaatga
     3781 gaactttagg gtttgcatat aaagaaatct cacaagctga agaagaagca gcagtaactg
     3841 ctgaaagtga tgctatgaat gtaagtgcaa tggaaaacaa tttagtattt agtggttttg
     3901 ttggtataag agacccactt agaaaagatg ttatagagtc tgtaaataca gcaaataaag
     3961 ctggtgtttc tgtaaaaatg cttacaggag ataatataaa tacggcaaga gctataggtg
     4021 aagagttagg cctattaaaa aataatatga gagtggttga agcttcatat atagatactt
     4081 tagatgatga agaattaaaa caagagatac aaagtatttc aatcgtggca agaagtaaac
     4141 cagatagtaa aatgagaata gtttcagctc tgcaaaagag cggagatgtt gttgcagtaa
     4201 caggtgatgg tataaatgat gctccagcac tttcaaaagc agatgttggt atagcaatgg
     4261 gtatatctgg tacagaggta tctaaaaacg cagcagacat aattttaact gatgatagtt
     4321 ttagtaccat tgtaaaaggt attaaatggg gtagaggaat ttatgataac ttccaaagat
     4381 tcgttcaatt ccaattaact gtaaatgtaa ttgcattttt agtggctata atatctcaag
     4441 ttatgggaca agagatgcca tttactacaa tacaattatt atgggtaaac atcattatgg
     4501 atggaccacc agcactagca ttaggtttag agccagttag ggaccatgtg ttaaatagaa
     4561 aacctgttga tagaaaagcc aatataattt ctaagtcaat ggtgtataca atagtattaa
     4621 atgcatttta tataacagca atactaatgt tacaatctac atttaatttc ttaggagttg
     4681 atgaagcgca taagggaaca gtaatgtttg cgttatttgc ttttagtgca ctgtttaatg
     4741 catttaactg tagagagttt aatgcagata gtatcttccc taattttaca cataacaaat
     4801 tagcactaca aataatagtg ttgacaggaa ttgcacaagt aatatttact cagctattcc
     4861 aagatttctt taactctgta gcaatggatt ttatgacatg ggtaaaagtt ttatgtgtag
     4921 cagcaagtgt aattgtggtt aatgaagttg taaaatgtat aataagactg gtaaaactaa
     4981 aaaagactgc ttaaaacaaa ttttttagaa gaaaacagac tgactcaaaa tatgaatttt
     5041 gggtcagttc tgaataaaca tttaaattgg gaggatagtt atgggtgact caaaggtatt
     5101 tgaaaaaata ttctccagcc aatcagatag aggaaattac actccttcaa agggatatct
     5161 aagttatttt atttcgtata ttggtttaga agatgaagtt ttgtacaatc tcgagatatt
     5221 taagacaaaa caaaatattg atagcaaaaa agatattgct ttatttactg atgttatagc
     5281 aaatcctagt gattttgata ttataaatta ttttaaaagt ggacttcaaa aatatagaac
     5341 tagcatggaa gatgtagata taaatatttt gggatttgaa gagattgatt ataaaataaa
     5401 gcaagcaatg gatagagtgt taaaagaaga ggaaaaagaa tttactaatg atagagttaa
     5461 acaaaatttt atagtgaaaa taatggcatg gataaaaatt tatatcggtg ctttagatat
     5521 aaataaaaat gaagctccaa aagtaatatt ttatggagat ataaaaaaac atgaagttta
     5581 tttactctta atattatact tggcaggttt tgatgtttta tatcttaatc caaattcaaa
     5641 gagtaatata gatattttaa aatcagaaag atacaatata gagtttgaag aagccaacat
     5701 aatagaagaa aaaatttctt ttgaagaaag ggttatttta ggggaaaaaa tagataaaag
     5761 ttctgtaaaa aaagctttta ctgttggggc agaagcatca aagcgtataa gtgaggaatt
     5821 gttaaatgat gcaggattta taaaaccttg gcaactccaa gatagaaaaa taaaaaatct
     5881 acttctaagt tcaactgttg atgaaatatc aatatactgg aatcaaccac ttaaattaag
     5941 accaggattt aagtttaatg atgctattgt agaagctcca aattttcttt ctaagattaa
     6001 tggaatatat aacgataaga atgaatatat taagttttta gatttattaa gagattcgga
     6061 aagttcaaca tttattgaat ttaatggaga tgtagataga ttttcaaaag cttttacaag
     6121 agaagctttt agtttatcct ttttattgga ttcaaaaggt gcaatagata aaaactctgt
     6181 tttaaataat aaagattatt ccatatcaac actagcattg aatcaacaaa ttatgatttt
     6241 agagaaagtg gaagagttgt tagaaggaag tatgtttttg aatggtttaa gtggagaaga
     6301 caagataaaa ggtctattta cagtacttca catggataag aaatttgttc atatgatgaa
     6361 caatttcgat tactcactta taaacccaaa attgattata tacatgtaca agagtattgt
     6421 atttgataaa gaaatagttt ttcttatgct tttacttagt aagattggat ttgatattat
     6481 catattatgt ccaggaggag aaaacaatat agagaatgtt ataaataacc aattgattga
     6541 tgtacacaga ttggataaaa tggtatatga ccttaaatta aattcgcttg aaaatgatat
     6601 acctttactt aaaaaaattt ttggaaagag gagacgattt tagatgggga taaatataaa
     6661 tagtttttca aaagataaga actctgtaga ggttactgaa aatttgccta cagcagttca
     6721 agaagaaaac ttcgatataa tggaatatac aaataataaa aaaaatgaac tgagaaagtc
     6781 taaggaagtt gaggcattga catctcttat agaagtagaa aatccagata cgattttaca
     6841 gtttggtagg aaagcatctg aaggagtagc aagagtttct gatagccttt taaatacaat
     6901 aaaattaaat agaaatgaag aaaattctaa aatgttggtt catttaacta aaataatgga
     6961 caagtttgat ttagacgatt ttcaagaaac taaggaacca aatttcgttc aaaaactttt
     7021 caaaaaagct aataatgcca ttgaaatgat gtttcaaaag tatgaaacat tgggaggaga
     7081 agttgagaaa attcaaattg agcttgaaca atacgaaaga gatatagcac tttctaataa
     7141 gcaaataggt gctatgttaa atgaaaactt tgagttttac aatgaacttc aaaaatatat
     7201 tgttgctgga gaaatggcaa tagaagaaat ggataatgaa atactacctt tctttaaaca
     7261 aaaatcagag actagtggag accaaatgga tgttgtcaat tatcaagaac tattaaaagt
     7321 ttatgatatg ttaaatcaaa gagtctatga tttaaggata gcagaaaata tagctatcca
     7381 aacaatacct atgcttagag gtatgcaaca taataattat ggtttaatta gaaaaataaa
     7441 tagtgcattt gtcgtaactt taccagtatt taaacaatgt ttatctcaag ctatattact
     7501 taaaaagcaa gaattacaag caaaatctct aaaagcactt gatgacaaaa ctaatgaatt
     7561 attgcttaga aatgcacaaa atgtaagtac tcaaagtgca caaatagcta gaatggctgg
     7621 aacaagttct gttcaaatag aaacattgga aaaaatgtac aatactatca agtctggtat
     7681 agatgaaact atgagaatag aagaaaacaa tagagcttta attaaggata atacaaagag
     7741 attggaagaa ttaaatacga ctataattta taataagtag tattatatta agggctaatt
     7801 tgtataaagt tggccctttc tatgtatatg aggaggctag acattgaaat atttcgatta
     7861 tatctgcaaa gatgatttgg agagaatttt tttgaaggag ccagaagatt ttagtgctaa
     7921 gactgaaaaa gatgtgttga aatatgcact gggcgctttt ttatacgttc cagctactca
     7981 atataatatg atttataaga gtattatagg ggatgttaag ggagttagac cattagctat
     8041 ttgtttagaa gatgctgttg gagtaaatgg agagttggag gctatagaaa atcttagatt
     8101 aattttaaaa aatattagca atgaaagtat aactaataaa gatggaatac cactaatttt
     8161 tgtaagaata aaagatgtgg agcaactgtt gagaattaaa gagattataa ttaaaaatag
     8221 tcattttata acaggaatat taattcctaa agcaaattcg gagttaattg aaaattgtat
     8281 agaagcttta gattttatga atcttcaaga tatgtatgtt attccgatag tagagacaaa
     8341 agaatttata tataatgaaa aaaaagaact tagttttact aatttgtaca atgctatttt
     8401 aagacataag tcaagaatat taagcattag agtaggcata actgatatat tagggatgta
     8461 tggtataagg agagataaaa acttttctat atataataat ttgatttgtt cttcatttat
     8521 attagatata atcacatatc ttcaaagacc agagttagat atacctataa gtggtggagt
     8581 atcagaattt tttgatatga cgaataagga tataagaaat aagtatatag aagaaatatt
     8641 attggataaa tatcatggat taattggaaa gaccgtaatt catccaatgc aaattcaaat
     8701 tgtacaagcg ctatctacag tatcatatga agattttact gatgctttgg atatactgga
     8761 tagtacagac agtaagtatg gtgtgagcaa gggtgtatta ggagagagaa tgaatgaaac
     8821 aaatccacat tttttatggg ctaaaaaaac attgattcta tctaaaatat atggtgtatt
     8881 aaataaagga gtagactatg aagaattgct taaattttaa ttgtgagatt gacattattg
     8941 ataatccatt gaatttagaa ctaaatgatt ttttagacgt aggaataaga aataatagca
     9001 aaagacgttt tttgtttatc tcaaagaaac tcggtaaaca tttagcatgt aagccaagtg
     9061 agatggataa tttgggaaaa ttaatggcta caatttataa tgaaaaaaat aaggaagaat
     9121 caaatggtac tgttatagct tttgctgaaa ctggtacagc tgttgggcat agtttttttg
     9181 attacttatg tggagattat gaatttattc atactactag agagcagttt gacgagttag
     9241 aaaatctgga atttttagag gaacattccc atgcaacaga ccagaattta tactttggta
     9301 tgcttaacaa ctttaaattt ggagatgaga taatattggt tgatgatgag attaccacag
     9361 ccaatacatg catgaatata attaggaaaa ttcaaagcat ttatcctaaa aagaaataca
     9421 ctatatgctc aatactcaat tgggtaagtg atgaaaattt aagtaaagtt actcgtttag
     9481 aaagagagct agattgtaag atagattttg tatacttatt taaaggaaac tttaaatttt
     9541 atatagatga agatattatt tcaaattaca acgataatta tagtattact aaattagaga
     9601 ctatttcaag tgataaagta aatttagtag taaatcatat ttatgttgat ttagaagatt
     9661 atattggaaa taagaaatat gtaaaatata caggaagatt tggaattaat agaagagaac
     9721 aatttagatt aaaagaaatc gttaagagag aaagtaaaaa aataactatg gccagtaaag
     9781 aatctttaaa aaatgaaaaa gaaaagattc tatttttagg tactgaagaa tttatgtata
     9841 tacctatgct gtttgcaaaa gaaaaagaaa atcaatatga tatatactat cattcaacaa
     9901 caagaagtcc aattattaat attgataaga ataattatcc tattaaaagt aaatttatgc
     9961 taaagagttt ttataatata gatattcaaa attatattta caatatagat aaacataatt
    10021 tttctaagtg ttatttattt gtagagctga ataaaagtga aaattcttat ctagaattta
    10081 ttgatataat taaaaaaaca agtataaaag aattaactat agtatgttgt agctaaagtg
    10141 ttttaacagg ataaaatata tcacgatttt aagataggag ttgagtcata tgagagattt
    10201 tagcacgtat tctaaagatg atgttatttt tttattaaaa gatatatcaa atttaattga
    10261 agaagaagga aataaagaaa gagaattaaa aatacaaaat ggtagacatt attcagaaat
    10321 gataccaata gagtatgaag ttagtgaaga ttatctgaat ttatatcatg agaaactaag
    10381 agaaaataaa gataaacttg cattttctat aggagttatg tgtgaaaaaa taattaaaaa
    10441 aaatggaaat gatgtagtac tagtttcact tgctagagca ggaacaccta ttggtatttt
    10501 ggcaaaaaga tatataagaa gcaagtataa tataagttta cctcactata caatctctat
    10561 aataagagat aagggaatag atatgaatgc aattgaatat atagtaaaga atcatccgag
    10621 ctcaaaaatt caatttttag atggatggac tggtaaggga actatatcaa aagaacttga
    10681 aaaagcatgt gatgaactta atgttaaatt taaaaaatat tttgactcaa cacttgctgt
    10741 attagctgac cctgctggat attcaggact ttatggaatt agagaagatt tcttaatacc
    10801 aagtgcatgt ttaaattcaa cagtttctgg tttagtaagt agaactgtac taagagagga
    10861 tttaattggt aaaaatgact tccatggagc taagttttat agacatttaa aagataaaga
    10921 tgaatctatg aactatatcg aaactataga agaatgtttt aaaaatcaat ttaagaatat
    10981 atctgatgaa gttgaaaact gggaaagtga cattataaca agagatggat actttgatgt
    11041 tttaaatata aaagaaaagt ataacataac agatattaac tttatcaaac caggtgtagg
    11101 ggaaacgaca agggttttac ttagaagagt tccgtataag attcttgtta aagacttaaa
    11161 tgataaatct ttagaccata tattcatatt agctaaggag aaaaatgttg aagttgaaca
    11221 aatggattta aaagcctata aatgttgtgg aataataaaa aatatgaaag atatttagga
    11281 aatatattag acaggagaat attgaatgat tgttttttca gatttagaca ggagtatcat
    11341 ttactccaat aaatttttaa atgctgatag taaatatact aatatagaaa tttataggga
    11401 aaaagaaata tcttatatat ctttagatac tataaattta ataaagcaaa tacaatatta
    11461 tggtatgttt atacctacaa ctactagaac agtggagcaa tttaagcgta tagaatttaa
    11521 taaatatggg atttattttc cttggagtat aacttcaaat ggaggagtta tacttaaaga
    11581 taatgaaata ttgaaatcat ggagtgaaaa aatagataaa ctaaaatgtg attatgagcc
    11641 cattgaaagt atgattcata aatttaaaga ctatttgaat gtagatggaa taactaattt
    11701 taaagttgca gaagatacat ttttttatat agttgttgat ttatcaagat ttaatttgga
    11761 ttcaatcaaa gaatatacaa atatattgga atcaaaaaat tggaagtttt atgtgagtgg
    11821 cagaaaaata tattttatac caaaagaaat ttcaaaagaa aatgctataa aatacttgac
    11881 taaagaatta ggaatagaat atttttatgc agttggagat tctattatgg actatggtat
    11941 gcttaatatc tcaaataaat cctatgtatt gaagcatggt gatataaata aaaatgaaat
    12001 agaaaattca tttatatcaa gttctttcaa tggaatgagt ggaactgaag agatactatc
    12061 taacatttta gacgagaact gcctacttaa tatataatga ctgatatata aataataaac
    12121 tagaaaaatc tgaaataaat tatagtaaag tttatcatac taatttattt cagattttta
    12181 tcaatttata tttaagtaag aactcaatat gttaaaatga aggtggagtc attgcccaga
    12241 ctgagataca tacctcatca tcataatttt catacacatg tggtatagta ctgttaaaat
    12301 aaaaactatc tccttcctcc aatagatatt ccttatttcc aagtgttatc ttcattttac
    12361 cttttattat atagccacat tcttctcctt cgtgtgtcac aaattcactg tttttttgtg
    12421 tatgaccatc tagtgtaaca agtataaatt ctattttttt cccagataaa ttaggaacaa
    12481 gaagttcata aaattttgta gaatcattag ttactatttt ttttcgatta tttttcttta
    12541 ctactatatc agagtcttct cttccaatct cttcaaaaaa ataacctata tttatatcaa
    12601 gagcttttga tattttccac attgctacaa tagatggaac aaccatatta cgctcaattt
    12661 gacttattaa gcctgtactt aaatctgaat tttttgctaa agtagagata cttatatttt
    12721 tagattttct aagagatcta attttgcttc caacatctat attcattaga tacaaacccc
    12781 ctcagacatg attataacat ataatttata aagattaata aaataaaaaa aaagttttac
    12841 aatacaagta ttttttatgc tatattgaat tttctgaaaa gatgcattat aatagtatta
    12901 atattcaata tattgaatat tgataacgat attttaattt aatgaaatgg aggtaattaa
    12961 gatgaagagt tttgtaagtc ctgataatat ttgggtatta tgggcagttg taactggatg
    13021 ggcagcattt agtatttatt tggaacaaaa gtacaattgg gcatcaaaag tgtcgggagc
    13081 aataatagct cttgtaggag caatgttatt atcaaatcta aatattatac cagtagagtc
    13141 tgttgtatat gaccaagtat ggggatatgt tgttccttta gccatagctt tattgttata
    13201 tcaatgtaac attaaaaaga tatggaaaga aagtggaaga ttgctcatta tatttcttgt
    13261 aggttctgta ggaactgtac ttggagctat gattggattt ttagcattaa aaaatgtagt
    13321 accagattta aatattgttg cagctatgat gacaggttct tatataggtg gaaatgtaaa
    13381 ctttgctgct atgtcagggg cgtttgatgc gccaggagaa ttagtatcag caacagttgt
    13441 agcagataat cttttaatgg cattatattt ctttgtctta atagctatac catcaattgg
    13501 attttttaga aaacatttta aacatccaca tgtagatgaa atggaaagta taggtataac
    13561 tgaaggagaa acagtagcag caaattattg gggaagaaaa gaaatatctt taaaagatat
    13621 agcaatagcc attggtagcg cctttataat tgttgcagta tctgtagaac tatcaacttg
    13681 gtttaaagct ataataccat tatcaaatcc ttttttagca atgttaaata ctttatttgg
    13741 aaatcaatat ctaataataa ctactttgac tatgttgttt gccacattta tgcctaattt
    13801 ctttggtgat ataaaaggag cacaggaatt gggtacattt ttaatatata tattctttgt
    13861 tgtagtaggt gttcctgctt caataacatt aataattcaa aaatcaccat tactactttt
    13921 atactgcgga ataatggtac taataaacat gctagttaca tttatagttg caaaaatatt
    13981 taagtttagt ttagaagaag ctattcttgc atctaatgca aatattggtg gtcctacaac
    14041 agcagcagct atggcaatat caaaaggatg gtctaagcta gtagggccaa tacttatagt
    14101 tggaacattt ggatacatag tcggtaatta ttttggtctt ttagtaggaa atattttgat
    14161 ataattttac gtgaaaaaaa gttgtttatt agaaagattt ttatttaatt ggaggttgtt
    14221 atgattttcg atggacattc agatacttgg gcagatgtaa caataagaag gcttaacggg
    14281 gaaaaagatg tatttagaag aatccatctt gataatttta aaagagcaaa tatagaagga
    14341 gctatttttg taatatggat agacccacca tatgataaag agcctgaaaa aagagttaaa
    14401 caaattataa gttctataaa agatgaaatt gaagatatga aagatgttgt aaacatagta
    14461 aaaaaatatt cagatataga taaaggtata agtgaaaaca aaataaatat tttaattggt
    14521 cttgaaggat taagccatat tggaagaaat atagatttac tagattattt ttataaagaa
    14581 gttggtgcaa gacatgcatc attaacttgg aatgaacaga atgaacttgc tacaggatgt
    14641 ttaggggatg aaaatcgtgg tttaagtgaa ataggcaaaa aagcagtcaa taaaatggaa
    14701 aaattgggca tgatagtaga tgtgtcacat ttaaatgaaa aatcattttg ggatttaatg
    14761 tctgttgcaa gtaagccagt tatagcttct cattctaatg ctaggagttt atgtgatgct
    14821 aaaagaaatc ttacagataa tcaattaaaa gaaatttcaa atacaggtgg attagttgga
    14881 ataaatagtt ttagaggatt tactaatagt aatcctaaga agcaagattt aatacatttg
    14941 gttgaccata tagactatat ggtaaatctt ataggtatag aacatgtatc ttttggtttt
    15001 gattttagtg attacttagg gaaagagact ataggttctt ttactggaaa tgctagtgtg
    15061 ccaagtgtag atggtcttga aagcacacat acagcacaga acatagtagt agagcttgaa
    15121 aatagaggtt ataaaaagaa agatatagag ttaatctcta gtggtaattt ttataggctc
    15181 tttaaagata tactaaaata atataataaa gaacttaaat ttataaaata gtatatttat
    15241 acaaataata tctacatatt taaattggcg ttcataattt attaaatttt aatgttacta
    15301 gaagtttcaa ttctagtaac attttttatg ttaaaaacag atatagatat gtattgacaa
    15361 tgataattat tattgataaa ctataaaagt gaaaatgata ataattttca ttttaattaa
    15421 taaaagattt ttaaggaggg agaatgaaga aaaggtattt agtcatagga ataataattt
    15481 tgtcttattt ttctttattt ataggagctg aagatataaa tataatgcat atatttgcca
    15541 aaaatcagca taaacttatg atatttatca tgagtagaat accaagatta ataagtatat
    15601 tgattgctgg tgtaggaatg agcatagcag gtcttataat gcaacagata agtaagaata
    15661 aatttgtatc acctacaaca ggtgctacaa tagatgcagc acaatttggg atagtaatat
    15721 gtatgctttt agtaccaact gcctctattt ttacaaagac aataatagca tttgtatttt
    15781 ctcttgtagg gacttttacg tttatgaaaa taatagggaa gttacaattt aaaaatataa
    15841 tctttgtacc attagtaggt ataatgtttg gaaatataat agggtctatg acggatttta
    15901 tcgcgtataa atacgatttg agtcaaaatg ttagttcttg gatgcaaggt gacttttcta
    15961 tgatacttaa aggaaattat gagatattat atatcacaat accccttata atattagcat
    16021 atatttatgc aaataaattt actgttgttg gtatgggtat ggattttgcg acaaacttag
    16081 gtcttagtta caaaagaatt gtcaatatag gtctgataat agtagcactt gttacagtat
    16141 gtgtagtcgt tacagctggt aatatccctt ttataggtct aatagttcca aatatcgtat
    16201 ccttgtacat gggtgataat ataagagcaa gcatatggta tactggttta cttggagcga
    16261 tatttgtact tatatgtgat atttttggaa gaattattat ttatccatat gaaatatcta
    16321 tagggcttac agttggagtt ataggaagta tactattcct ttatttaata ttaaggagga
    16381 atgtgaatga agcttagtct caatcaaaaa atttactttg taagtatatt actattcata
    16441 tcaatggcac tttttataat ttatggaata gacatgaatc atttagaata tgcattatca
    16501 caaagaatac caaaaatatt tgctatggta ttaggtggag gatgtatagc atttactact
    16561 gtagtgtttc aaacaattac aaacaatcaa atattaacac caagtgtact aggtttagat
    16621 tcattgtatg taatgattca aactataata gtattcatat ttggttcaag cagtagtctg
    16681 attataaatg aaaattataa ttttattatt aatgtagcta tgatgattgg agcttcattg
    16741 ttattatata agacgttatt tgaaaaaaat aaaaataata ttttcttttt aatcctagta
    16801 ggaatgatat ttggaacctt atttaaaagt gcaacaacat ttattcaggt aatgatagac
    16861 cctaatgaat ttttagcttt acaaactagt ataatggcaa gtttaaacaa tataaacact
    16921 aatgtattgt taatagcatt tataataatt attgccataa taccttttat atatgatgaa
    16981 ataaagtatt tagatgtatt gtcgttaggt aaagaacaag caattaattt aggtgtagat
    17041 tttgataaag cagttaaaaa aatgataata ttaatagcaa ttttagtctc aatatcaaca
    17101 gcacttattg gacctatgac atttttagga cttttacttg ctaatataac aagagaaatt
    17161 tttaaaacat ataagcatac atacttgatt tcgggttcta tgttgatagg gatgattaca
    17221 ttgataatag gtcaattttt tatacaacat gtatttaagt ttgatacaac tttaagtgta
    17281 gtaataaatt ttataggagg aatttatttt attcaattac tattaaaggg ggcaaataga
    17341 tgatagagat aaaaaatata tttaaaagat ataagaataa aaatgttgta gatgatgtct
    17401 cttttagtat agaaaaggga aagataacat cttttatagg accaaatgga gctggaaaaa
    17461 gtacagtact atcaatagtt acaagactta taggaggtga tggtggagaa gtaataatag
    17521 aaggaaaaag cttgactaat tatagcaata aagaattagc aaaaaaaata gctattctta
    17581 aacaatctaa caatataact ttaaagctta caataagaga attagttgga tttggaagat
    17641 ttccatatag tgaaggtaat ctaactaaag aggatgaaaa ttatattgat gaagcaatag
    17701 aatatatgaa gttgactgat atacaacata agtatttaga tgaattgagt ggaggtcaaa
    17761 gacaaagagc ttatatagca atggtaatag ctcaagatac agagtacata ttacttgatg
    17821 aaccactgaa caatttggat atgaaccatt ccgtacagat gatgaaggta cttagaggtc
    17881 tttgtgatga attagataag actatagtat tagtaatgca tgatataaat tttgcatcat
    17941 gttattcaga taatatagtt gcattaaaaa atggaaaagt tgaaaaagta ggtcgtacag
    18001 atgagatagt aaatgaaaaa gttttagaag atatttatga gatgaatttt aacattaaga
    18061 atataaatgg aaatcgaatc tgtatttatt tttaaaatat tgtatatgaa aataaacttg
    18121 ctatatgatt ttttataaag tttttaaatt aaaataaaga ttaataggag agaggaaaat
    18181 attgatatga ataaaaaagc agcaatagta gcagcagtag ctattatagg attagtgaca
    18241 gtgtttgcat taggtggaag taaaaagaat gaatcaaaaa catcagaaaa ttcaaataat
    18301 actatgaaga taactcataa cttgggagaa acagatgtaa aattaaatcc taaaaaagta
    18361 gtggtatttg attattcggc tttagataca atggatgcat taggtgtagc tgagacttta
    18421 gtaggacttc caaaagcgag tttaccagca tccttagaaa aatataagga tgacaagtat
    18481 gcagatttag gaggattaaa agaaccagat ttagaaggta taaagtcggc aaatccagat
    18541 ttaattataa taaatggaag acaagaagat ttttatgagc aattgtcaaa aatagcacca
    18601 acaataagta caagtaaaga tgataagaag tacttagaat ctgttaaaaa taatatagac
    18661 aaaatagcaa aaatatttgg agtagaagaa aaagcaaatc aagaatttag taaaattgaa
    18721 aagaaaatag aaactttgaa taaaaaagta acagataaaa atttaaatgc tttaactata
    18781 atggtaaatg aaggtaattt aagtgtattt ggtgaagaat caagatttag tatattatac
    18841 aatagttttg gatttgaaaa taaagataaa aatataaaag aatcaagtca tggacaaaat
    18901 attacttttg aatatatagc taaacaaaat ccagaagtta tgttcgttat agatagagga
    18961 atagctactg gcagtgatgt aaaagaaagc tcaactgcaa aatctgtttt gaacaatgat
    19021 ataataaaat ctatggatgc atataagaat gataatataa tatatttaga ttcaccaaca
    19081 tggtatgtaa atgatggtgg tctaacatct ttaaataaaa tgatagatga tgcttcaaaa
    19141 gcggtaaatt aataatccga tataaccaaa atgtattttt tataaaatga ttatcaaata
    19201 aactaggagt ttttaagaac tcctagttta ttttttgcat aaaaaagata tagttt
//
LOCUS       DAEHWO010000081        19149 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEHWO010000081 DAEHWO010000000
VERSION     DAEHWO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19149
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.081"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            104..859
                     /locus_tag="KNP54_003161"
     CDS             104..859
                     /locus_tag="KNP54_003161"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBF0894026.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            complement(1366..3042)
                     /gene="bclA2"
                     /locus_tag="KNP54_003162"
     CDS             complement(1366..3042)
                     /gene="bclA2"
                     /locus_tag="KNP54_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBF0894027.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(3420..3959)
                     /gene="hpt"
                     /locus_tag="KNP54_003163"
     CDS             complement(3420..3959)
                     /gene="hpt"
                     /locus_tag="KNP54_003163"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBF0894028.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(4287..5594)
                     /locus_tag="KNP54_003164"
     CDS             complement(4287..5594)
                     /locus_tag="KNP54_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBF0894029.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(6019..7794)
                     /locus_tag="KNP54_003165"
     CDS             complement(6019..7794)
                     /locus_tag="KNP54_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0894030.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLERMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(7791..7928)
                     /locus_tag="KNP54_003166"
     CDS             complement(7791..7928)
                     /locus_tag="KNP54_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894031.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(8006..8575)
                     /locus_tag="KNP54_003167"
     CDS             complement(8006..8575)
                     /locus_tag="KNP54_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBF0894032.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(8759..9394)
                     /locus_tag="KNP54_003168"
     CDS             complement(8759..9394)
                     /locus_tag="KNP54_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBF0894033.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(10062..10943)
                     /locus_tag="KNP54_003169"
     CDS             complement(10062..10943)
                     /locus_tag="KNP54_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBF0894034.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGAKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(11063..12070)
                     /locus_tag="KNP54_003170"
     CDS             complement(11063..12070)
                     /locus_tag="KNP54_003170"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBF0894035.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(12090..12572)
                     /locus_tag="KNP54_003171"
     CDS             complement(12090..12572)
                     /locus_tag="KNP54_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBF0894036.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            complement(12590..13057)
                     /locus_tag="KNP54_003172"
     CDS             complement(12590..13057)
                     /locus_tag="KNP54_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBF0894037.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(13072..13830)
                     /gene="prdD"
                     /locus_tag="KNP54_003173"
     CDS             complement(13072..13830)
                     /gene="prdD"
                     /locus_tag="KNP54_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBF0894038.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(13910..14635)
                     /gene="prdB"
                     /locus_tag="KNP54_003174"
     CDS             complement(13910..14635)
                     /gene="prdB"
                     /locus_tag="KNP54_003174"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(14183..14185),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBF0894039.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(14673..14957)
                     /locus_tag="KNP54_003175"
     CDS             complement(14673..14957)
                     /locus_tag="KNP54_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894040.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(15038..16918)
                     /gene="prdA"
                     /locus_tag="KNP54_003176"
     CDS             complement(15038..16918)
                     /gene="prdA"
                     /locus_tag="KNP54_003176"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBF0894041.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(17347..19107)
                     /gene="prdR"
                     /locus_tag="KNP54_003177"
     CDS             complement(17347..19107)
                     /gene="prdR"
                     /locus_tag="KNP54_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBF0894042.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
BASE COUNT         5595 a         3693 c         2304 g         7557 t
ORIGIN      
        1 tgtaagctta ttatcactaa tattatttta tataaattat attagtgata aaataaactt
       61 atagaaatat aacaaatttt tattaatttc ataggaggaa tttatgttga aagttataat
      121 tagtggctat aatggaacaa tgggaagagt tttagcagaa tgtgtaaaaa aagataatga
      181 attagagttg gtttgtggtg tagctaggtc tgctgatgaa aaaggtcatc atagtgatac
      241 aaagctttac aaaacaatga ctgatgtaac tgaaaaaact gatgtaataa tagacttttc
      301 acatcatgag actttagagc caatattgtc atatgctcta aaaaataata cacctgtagt
      361 attagctact actggatatg atgaaaatga cttaaataaa atagaagaag catcaaaaaa
      421 cattcctata ttattatcat caaatacatc tcttggagtg aatatattaa taaaattagt
      481 taaggatgct tcaaagatgt tagaaggttt tgatattgaa atcatagaaa aacatcacaa
      541 tagaaaagaa gacgccccta gtggaactgc tactatgata gctaatgcaa ttagagaagt
      601 cttgcctgaa agtgaaaata cacatggtag atatggtaga gattgtaaaa gaaaaccaaa
      661 tgaaattgga atacactcta taagaggtgg caatataatc agcgaccatg atgttgtatt
      721 tgcaggtgat aatgaagttc ttacattaag ccatcattct caatctgatg aagtatttgc
      781 aaacggttct atagttgcag ctaaattttt aattggtaag caatctgggc tttataaaat
      841 gtcagatata ttaggataag ttttgtacat aataaatctc aatctattta ggtattcata
      901 ttcatcaatt tgaatatcta attgattgag atttctattc taaaagttta taaattttat
      961 gtttaccttt taaatataat catttttctt aaagattatc ttatttattg gtatatggaa
     1021 ttatattgtt tattatttta taatctcttc atcatataaa cctattaaat attatcctat
     1081 ttattggtat atggaatcat attgtttatt attttataat cttttcatca tataaaccta
     1141 ttaaatatta tcctaattta ttggtatatg aaatcatatt gtttattatt ttatagtctt
     1201 ttcatcatat aaacctatta aatattatcc tatttattgg tatatgaaat catattgttt
     1261 attattttat agtcttttca tcatataaac ctattaaata ttattctatt tattggtata
     1321 tgaaatcata ttgtttatta ttttataatc ttttcatcat ataaactatt gtattctata
     1381 aactgataca tatccagctg cagaagtacc tgtcgtgcct gaaccaaatg taaaacttaa
     1441 agtaacagct gctgctctag catcaactaa aaagcttaaa cttacactta catctgatga
     1501 agtaagtgta tttactgctt ttgcaataaa gttattttga gctactccat taaagttagt
     1561 agtaattgac ataaatcctg caagtgaaag tgtggcacgt ataccgaaag atacattgta
     1621 tatccctcca actgcaagat ttatagtact acttgttgga aaagttatat tagttccatt
     1681 tataaatgat gaattaaatg tcactaatgt attattcact aaacttgaag aggacactgt
     1741 aaattgtgca ttgtttgctg ctaacactcc tgttgctccg gtcgctccgg ttggacctgt
     1801 tgctccattt gctcctgttg ctccggtcgc ccctgttgct cctgtcgctc catttgctcc
     1861 agttgggcct gttggtccta tcgctcctgc tactccattt gctcccgttg ctcctactgc
     1921 tccggttggg cctgttgctc catttgcccc tgttgctcct gtcgctcctg ttgctcctgc
     1981 tactccattt gctccggttg gacctgttgg acctattgga cctgctactc cattcgctcc
     2041 ggttgctcct actgctcccg ttgggcctgt tgctccattt gcccctgttg ctcctgtcgc
     2101 tccggttgga cctactgctc catctgctcc cgttgggcct gttgctccta ctgctcctgt
     2161 tggacctatt gccccagcta ctcctgttgc tcctgtcgct cctgttggac ctaccaaacc
     2221 atttgctcca gttgctccgg ttgggcctgt tgggcctacc aaaccatttg ctccagttgc
     2281 tccggttggg cctgttgggc ctgttggacc taccaaacca tctggacctg ttgctcctac
     2341 tgctcctgtt ggacctacct ctccatctgc tcctgttgct ccggttgctc ctattgggcc
     2401 tgttgcccca gttgttcctg ttgctcctgt cgctcctata cttccggttg gacctgttgc
     2461 tcctgtattt cctgttgggc ctgtagcacc tgttactcca tttgctccgg ttgctcctgt
     2521 atttcctgtt ggacctgtta ttccatttgc tccggttgct ccggttgctc cagttagtcc
     2581 ggttggacct gttgctccag ttgctcctgt attccctgtt ggacctgtta ttccatttgc
     2641 tccagtcgct cctgtatttc ctgttggtcc tgtagagcct gttattccat ttgctccagt
     2701 tgctcctttg tttcctgttg gacctgttat tccatttgct ccggttgctc ctgtattccc
     2761 tgtcggacct gttattccat tcgctccagt cgctcctgta tttcctgttg gtcctgtaga
     2821 gcctgttgtt ccatttgctc cagtcgctcc catatttcct gttggtcccg ttattccatt
     2881 cgccccggtt gctcccgtat ttcctgttgg acctgttatt ccatttgctc cggtcgctcc
     2941 agttgcacct ctaggccccg tcggtcctgt tggaccagta gcacctgttg gccctgttgg
     3001 acctacatct tgatataaac ttggacctga aatatcactc atataattaa tcctcctttt
     3061 ttaaagttag agtattactc tataaatatt gagtattact ctatataatt atatgaatcg
     3121 acaatttctt atgtgataat gtatctattt gcttatatca acatatatgc tttgattctt
     3181 gaatttcatt acttttttgt aaaatctttt acaattatta gtactctttt acaattatta
     3241 atacaattaa aaaactcatt ttccatcaat tatttaaaat ttttttatta tgttataaaa
     3301 aatagataat taaattgcat aaaattaatt taatactact ttaattactt tgtaaataaa
     3361 aaaacctcaa cacgattaat aaaaatcata ttaaggcatc cacaaaatta tataattgct
     3421 tatctatctt catcagtaac attgaatata taaggaacat ttctataata atcaccaaaa
     3481 tcaaacccat atccaaccac aaacttatct tctatttcaa atccacaata atctggcact
     3541 aaatcgactt ttcttctgct tggtttatcc aaaagaacac aacattttaa actagcagga
     3601 tttttagctt ttaaatgttt taacacaaaa tccatagtaa gtgcagaatc agtaatatcg
     3661 tctacaacca aaacatcata tcctgctata tcagtagtca catctgaaac tactttaacc
     3721 cttccagtac tttcttcatt gtttccataa ctagatgtag tcataaaatt aactctaagt
     3781 ggtaaattta tatttctaac taagtctgca caaaatataa agctaccttt taatagagaa
     3841 actaccataa gatttttatc tttataatct ttttctataa ttgctcctaa ttcccttaat
     3901 ttatctttaa ttttttcttc tgaatacaat acttcccatt tttttgtttc tatatccata
     3961 aaaagacctc caattgtaat aatccttctt aattttataa gagattgctc actttttcaa
     4021 tactcttatt caatattagt caatattatt gagtttttat gttcattcaa caattattaa
     4081 caatgtatct tatattttaa gtagttcata tatccacact aaattacata ctatatattt
     4141 tagacaaaaa aagaaaaaac ttgcactaac aagttttttc tattatacat aaatttatac
     4201 ataatcatat tttattagag ggtactaatt aaatttattt atgctatttt tgttatacct
     4261 cataatacaa aacatattat aaagtactag tcaactttat tcatatcatt cattacattt
     4321 aagattatct catctgttat agacatacct ttgtcactta ctctacctaa gttttgtata
     4381 ctttgctcaa cacttgaacc aactatacca tttagtggtg gtacaaaaca atcttgctta
     4441 gctattatag cactttgtat agctgcagat gctgcagaag ataattttaa tgcacaacca
     4501 gctttcgcac cgtcacatat cattccactt aagtcagcta tcatattttc tatagctcct
     4561 tctatttgct tttcagtacc attcataagc caagagatac cagcagttgc tccagtagaa
     4621 gcagcaacac cacatccaca tacagcagat aatcttcctg tatagttctt aatataacca
     4681 gttactagat gagatatagc taaagctttt gctagtcttt catcagattg tgggaatttt
     4741 ttattataag caacgattgg aagaattgct gttaatccat gatttccact tccatttgaa
     4801 ctcataacag gcatttttac ccctgccatt cttgcatctg aagctccagc agttaacatc
     4861 attgcataat ttataacatc attacctaaa agaccttctt ctatagactt tttaattcca
     4921 tacccgacac caataccagt tttttgtttt aatccatatt cagccatctc ttcattcatt
     4981 tttactccat ctagtaaaaa ttctatatct ttaaaatcaa tttcttctac attttttatt
     5041 aattcttgta tagttactgt atccattaaa ctttcagctt tttctgccgc atcatttgaa
     5101 gctgatactt ttggttcatt gtctaataat acttctccat ctttttctaa gaacgtaaaa
     5161 ttatcatgtt tagttcttat tctcacttta gcaatatgat tttttccttt taacacaact
     5221 tctataaata ctttctctct tgtatcagca ggtgttattg atagtggagt attatccata
     5281 taatcctcag ctattttaac ttcctctttt gttagagttt ctaacacact taatccattt
     5341 tcagaatgtc cacctactat acctagagct gctgcaattt ttaatcctaa tctttcagta
     5401 cctggtatac ctacacacat accattttta tagatactag gactaactaa catacgattt
     5461 tcaactattt cttctcctaa taattccttt gcctttgcac atgctagagc taaggctact
     5521 ggttcagtac accctactgc tggtttaact tctgccttta acatttccac taattctttt
     5581 cttatatctc tcattatata taaacctccc aattaagttt agatttagta ctcaaataat
     5641 tagttaaata atttcttatc tatatttata gcaaaataca tgccatattt tttatatctt
     5701 tttatatttt tagtcttata ttctataacc attggtatga ctgcctctat ttatgtattt
     5761 tttttatttg tatagagtat ttatattctt taaaatggag aaacatatga caatttcgca
     5821 aaaagacaaa aaaaagtctc aaaatgagat tctatatcat tttgagacgg ctcaaatata
     5881 ttatttttta acttataaaa accatttttt aattcataaa aaaagattct gcaaaacact
     5941 tatagtataa gtttaaagct ttctttaaag ttatgaattt agaaaaattt aaattttata
     6001 tagcttttta ttatattact atgaaattat attgtatttt tcaatttttc tatataatgt
     6061 agctcttgat attccaagtg ctttagctgt taattcttta tcttttttat aatctttata
     6121 cttatttaaa gcttttatta tctcaatctt ctctagttca tcaagtggaa ttatcctatc
     6181 gcttttaact tctaactctt ctacagaggt attcttaatt ttttgaggaa ttacattcat
     6241 tgtgattatt gaagaagaag acatattcac actatattca ataatattct gcaactctct
     6301 tatattccct ggccacttat attccatcat agcatcaaca accctgctat ctatgtcaat
     6361 aacattttta tctaattttt ttgaatactc tttaaccata tgcttgatta taagtgggat
     6421 atcttctttt ctctctctta aacttggtaa ttttataggt ataacattta atctataata
     6481 taaatcttct ctaaaagtgc cattttgaac cattctttct aaatctttat ttgtagcagc
     6541 aataattctt acatctattg aaacatttga tttacttcca attttattaa gttccttttc
     6601 ttgtaatact ctcaataact ttgactgtaa atgcaaactc atatctccta tttcatctaa
     6661 aaatatactt cccttatgag ctacttcaaa cattccaagc tttccacctt ttttagctcc
     6721 agtaaaagct ccctcttcat atccaaataa ttcactctct aataaattat ccggtatagc
     6781 agcacagttt acagctataa aaggattatc tactctattg ctatggttgt gtatggctct
     6841 tgcaaatagc tccttacccg ttccactttc cccagtaata agtactgttg atgttgattt
     6901 agaagctatt agggcttcct ttttagaatt tcttatagct acactttctc caattatgtt
     6961 ttccaatttt attctataat ctttattcat cttattgtag ttttttatag catctctttt
     7021 atctataaaa tcaataacat atccctttaa ctcatttttt aatactattt tattgatgtt
     7081 gtatattccc ttcgaatcat atccgtatct tttataaaaa aaactacagg atttgtcctt
     7141 cttaaagtta tttatagaag gtttctttat aaaatctaac tcgacaaata tgtttttgcc
     7201 agttatacta tcttttatat tgaaaagctc tttaaatttt gaattatatt tatcaatttt
     7261 tccatccaca tcaatagaca caacagcttt gtccatattg tttaatagtg tctctaattt
     7321 tttcttttct aattcaagct cataagtttt aatttgtgct tttaatttat tagatattag
     7381 gtctgccatt ttgcctaaaa agtttataag accactttta ttattttcta taatttgtgc
     7441 ttgttctttt gtaaaggcta taaggcctat aacaccatga gaatcgccat cacatataat
     7501 aggacaacac acctctgcaa actctacaca agccccactt ttatagcatt ccctacatat
     7561 atcactactc tttgggtcat caattagtat tgtaatctgt tctgtaagtg attttttaaa
     7621 agccgtatat ttatctactt tctcacctat tttgtctata tatactcctg tacctgcaat
     7681 cctaaataac tccttattta ctatagttac atctatattg agtactgata ctatagcttc
     7741 agctatattt tgaatatcag attttatata ttctaaacct atcataatca tcattcctta
     7801 tttttcttta gcataagtat ttgtcttatt tctttaagaa tcaagtatat cttatttaaa
     7861 gtaaattgga ttgacatcag gattacaaag agcataacaa ttattattaa ctcataattt
     7921 atttccatct aaacatctcc ttataacaaa agactaggct taacctagtc ttttatatta
     7981 tatccatatt tatattttaa ctcatttatc ttctttttcc cacataaata tattttaatt
     8041 tatttgactc tttaatcata ccatcaaagt ttaatcttga aaatatatta aatacttcat
     8101 gtggatagtg aatctttgca acagaaccac aaaatttatg tttaagatag tttaacttaa
     8161 cttttaaatt ttttaaattt aaatcctcta atataacctc tccattgccc tttaacactc
     8221 tttgtatttc agatgaagct ttttcacaat ctgtaataac attaaattgg tcaactatta
     8281 ttatcttgtt gaactgatta tcatcaaatg gtagaaactc taacttacct ttaactacat
     8341 tgcaattttc attatacact agagaataac agacatcttc ataattacta ttctccagta
     8401 tagttacaga agttccaaga cctctcaatc tcttgcctag gtttcctata tgaccaacaa
     8461 gcaatatttt atcacctaca ttatactcaa ttgtatccaa aaaacattct aattcatcag
     8521 atgtatattt agctttaact ggctgtttat ttatctgaca taatatgctt ttcacaatgc
     8581 ttcacctctt catttcctca attataaatt atgtacagat tacattataa taaatggcga
     8641 gcaactattc aagagatatt tcattagtat ttttttaaac aatctttata cattttaata
     8701 tgatattata ccaaatttat taggatttta ttcataaaaa tcagtctatt ttttatgttt
     8761 attcattgtt attttcatcc aattttttta ttttcgatat ggatacttca tatgccattt
     8821 ttttgaccac attattttca tctatttttt tctcatattc tctactttga accctacccc
     8881 aaagctgtat tctatcacca acctttagat tctttgcaaa tttagcattt ctaccccaaa
     8941 ctattgatgg tatataatca gatttattat aaggtctgtt tatagcaact aataaatcgg
     9001 ttatttccct tcctaaaggt gtcttcctat acacaggttc cttacataca tatccatcta
     9061 aaaatatact attagggtct ttattttcct cgtctatact ttttatttct ctgacaaaca
     9121 ctgtaagcac taatctattt ttattattta atgttttgtt atatgatctt aattggccta
     9181 cgacattgac taaattttgt ttatcaaggt caatatcttg gagaagtctt tctgatacag
     9241 tcattggaag tatatcaaaa gaatcgctta gtctgtttat ttttattttc atattataaa
     9301 atttttctcc aaatatctca tggctaaatt ctagcttatt gtctaactcc cctcttaagt
     9361 ttactacgtt attctcatct ttaacagcta tcatatttta tccctccaca attgttaatt
     9421 cttatatttc tggtatcagc ttatataata aatatattta taagggatgt attttattac
     9481 aaatctttga ttgctgttta aaagttttta tttagttata aatttcattt aatatttcac
     9541 ttttataatt ataaaattat tatctttttg taccacatat actaattaaa ctacctattt
     9601 cagttttgta ttaattataa aaatcctatt atataattaa taagtcatat ataacttaaa
     9661 tttattcact ctatataagc aacttcaacg aattaaattt attgaaataa ttcagatgaa
     9721 tattgagtca ttataaactt atttttctta attataagtt atattagact tattacaggt
     9781 tatattttta ttaatctgta ttaatatatg aacatttatt gaacttattg attataaaat
     9841 ttaaatattt agctttaaat tatgctttat tctttaaaaa tacaacgttt tttagattaa
     9901 atctactaaa tcactatata tattacataa ttggcatgtt aattgcttta tattaattta
     9961 gtaaataaaa aactgcccta aaatattaat tcaatatttt aaagcagttt ataatcttta
    10021 ttattagctg taatatttaa taaacactaa gtagtcttta actaagcagt ctttttgttt
    10081 ttatttgcag ccattatcat tgtagcagaa gtataagcta taactactat tactaatgct
    10141 tttaatatat ccattggtag agtttttact atatatgcag ctacgaaaac tcctattaaa
    10201 ccacatatag ctattataac tgatgctttt ttagtatatg catcttcttt tatgaatttc
    10261 atacttgcaa ctggcattaa taatgcacaa gaacccataa ctattgggaa tgcaactttt
    10321 gcagacattc ctaagaaata aaccattgcc atacctggag catatagacc tataccagct
    10381 gtcattaaag ctcctagtat aaagttacct attacaccta ttactaattt agcaccagta
    10441 agacctaatt catttcctcc acctggtaat acgttaatcc aaggatgacc taataacatt
    10501 aatattgctg ttaatgctaa agttacaccc ataacaagtt gtatttttct ctcgtccatc
    10561 ttagctatta ttcctgcacc tatatatgaa ccaactgctg ctgccacaac catagatact
    10621 aaagtaacac catctactgg gataattgat gtaaatatga atgcttctgt aacaactgga
    10681 atagtatgtg ctacgtttaa tgtaccaggc atttttttat ctggtatatt taactttaaa
    10741 gcctttgaca ttgctattgt tggagcaaat gaccctattc ctaatgtatc aaagaagtct
    10801 gttataaatc ctgttacagc aacttttgga gtactttgtt cttctagttt cccctctttg
    10861 tttgctttag ctacgtcttt accaaacaca actgcaaaga ttgctgcgaa tactacatat
    10921 aatgccttta agattgctac cataatccat cctcctattt ttttattttt tcatatattc
    10981 tgaatcttat agcctaaaag ctatagaata gcaaccgaca agtggctact attctatttt
    11041 aatttcctaa tttatttatt acttatttaa gaataaatcc atgtttaagt gggtcttctt
    11101 catctattac aaaatgatta aatccagtta tataagcaga accagttatt ttaggtacta
    11161 cagcattgaa atctgcaact ttagtttctt caactatttc acctttgaat aaagttccta
    11221 atatactttc atatacgaat ttttctccta cttttaattc acctttagca tgtaaagtag
    11281 ctaatttagc acttgttcca gttccacatg gagatctgtc aacttgacct tgaccaaata
    11341 taactacatt tttgtaagta gcttctggat gagttggctc atcatatatt tcaactaagt
    11401 ctacagtttt tatatgagct aaagttggat gttgtatttc tattttctca tttattatat
    11461 ctctaagttt catagctagt tcagttaatt taccagcatt ttgaggttcg atttttaaac
    11521 ctaattgact tgcatgtatt atagcaaaga agcttccacc aaatgatatg tcaaatttaa
    11581 cagttccaac acctggtaag tcaacttcaa caccttcttt atataagaaa gctggtacgt
    11641 ttaagaatga tacttcttta gcttttccat ctacaactgt aacgtctcct cttattattc
    11701 ctgctggagc ttccataact acatgagtta caggctctac tgctggaact acacctgttt
    11761 ctatagctgc tgtcatagct cctattgtac catggccaca catgttaagg tatccgccac
    11821 catccatgaa gattattcca aagtcagcat ctgggcaaca aggttgagtc attacagaac
    11881 caaacatatc attatgtcct cttggctcta acattatagc agttcttaaa taatctagat
    11941 tttcctctaa atattctttt ttctcaggca tagaatttcc ttttatgtta ggtattccac
    12001 ctacaactat tctagtcgct tcacctgctg tatgagagtc tatagcttgt atacttctgc
    12061 taaatttcat atcaaattcc cccttaggtt tattttgcgt ctttacgcat ttttaatttt
    12121 aggaaagcca atgctttttt aacatcaact tcatccatgt gattgtctcc aactacttct
    12181 gtttctatgt agcctgttgt ctttttataa tcaattatgg tagctttatc caaatatgga
    12241 ttggtaatta ctaatccatc tgctcccata atagtaagac ctactgtagg tatatctgat
    12301 tttacaaact ctgctatagc atttgtaaaa tcaatatgct ggtttcctgc catatctaaa
    12361 gttataatca ctccatcagg tcgcaatgat tcaatccatc ttccaagtct agttgctaaa
    12421 aatgttttcc attcattgtg ctctgatgtc ccaactacaa ccactcctaa caagtctatg
    12481 tcagaatcat tatctatcaa atctagtaac gggtctctaa atatatgaag tgatgtgttt
    12541 ttcattgatg tagaaattcc cacaaaactc attcccttac ttaaattttt tatccatgtt
    12601 ttctcatttt aagttttaaa aatgccaaag cttttttagc atctatttca tttgtgttgt
    12661 tttctccaac tacttctgtc tcaatacctt cttttgattt gttcatatca actatggtat
    12721 ccatatattg attgcttaca acaaacttag cttgagtccc attaaatgta actccaacta
    12781 caggtatatc tctttttcct atttcctcaa atgtgttagc gtagtcaaca tgtgagtttc
    12841 cccaaccatc tgatgaaact atagctccat ctactctcat ggcttccagc caagcggccg
    12901 ttctttgtcc cacaaaggtt ttattttcat ttccatctgg agttcctact actattactc
    12961 caagtaaatc tacatcctta tcactttcaa ctatgtctaa aagtgggtct ctaaagtgat
    13021 gaagagatgt ttcttttgtt gaaggtccta ttcccataat atccacctct cttaagtcat
    13081 agctctaagg gcaccatctc tgtattcatt aggagatata atcataggta catttcccat
    13141 atctataatt gatgttcctc cttcaaatcc actaggttcc tttgagaata actgattgtc
    13201 atacatagca ccttgacctg ctatttgttt tactatgaca accttttttg catttggtcg
    13261 aattttgtca aaatattcac gaacttgagt agcatttctt ccgtcttcca ttttcaaaga
    13321 cgctcttatt tcttgtataa aatcatcaca tgctctgaat gctgcaagtg gaagtgttct
    13381 ttcaaaaggt aaacctccct ttaaagttac atctacatgg attatataat cttcaactga
    13441 tggagttcca tatctcccaa ataccatttg gtctttcaaa attccttctg aagaaccaaa
    13501 ttcatgcatt tgatttccat cttcatctgc accagttaac attacatata cacccgttaa
    13561 agtatgtgta ataccctctc ccagtctgcc taaaactttt gttgatattg gtataatgtc
    13621 cataatagta ttaatttctc tgtcataatc tccaggtttt ataatgtcta cttttatgtc
    13681 tgttattaac tcttctcttt cttttatttc atctatactt gataaatcta ttgtaagtac
    13741 atctttcttt atagaagttt ttgaaccgaa attaacttca ttcatatgaa acggttttat
    13801 aacaagtctt ctcattattt tttcttccat aatatccacc tttgttctta aaacccctct
    13861 cctaaccgtg taggagaagg gttctatatt ttcaaatata aattacattt taaacgtgag
    13921 ctttatattc gtatggtaat ggaactatct taccagcaga tggtattgca actaattgct
    13981 ctaatgtatc tcttaatata tgtgtttgca tttctatatt atgtggttca ccagcattag
    14041 cacccattgg aactaatgga gcaactgctc taggagttcc gttttgtcta actactggag
    14101 gaagagctgc tattattatt gtaggtattc cagcttcctc tattgctctc tgcacgatca
    14161 cggcagttct atggcaagta cctcagccag ctgtcataac tacaccgtct actccctctt
    14221 ccttaagttt agcagcgata gcaggaccag tttcttcagt gaagacatgt tggtttcctc
    14281 caccacccat gaatgcatag tgcataggag ctactccttt gataaatcct tctgcagcta
    14341 attcatgtaa tctatctata gggaacatac agtttatatc tttgtttaca tctccattgt
    14401 catatccacc atgtgatacc atcatttcat caactgtagc tgtattaggt atagctctaa
    14461 atgtagtatc tcctgctaga ttaaatctct tgtcagattt taaatgaaca ccagctgctg
    14521 tagctaaagc tatagtcata tcttttaatt ctttagttac aggagtccaa actggaggag
    14581 gtgttattgg aacgaatatt tcagattgaa gtccttgtac tgttgtaagg ctcatatatt
    14641 tcctctccct tctattttca aacgattatt tattattttt cttcttgttt tgattgcatt
    14701 tctgcttgtt tttctttttc tctcctaata ttttctacat actcttgatt aggctctgga
    14761 cttaatacct caggatagct tagcatgaat ccaacttctt gacctatctt aagttcgtag
    14821 tcagttataa gcattctatt aggtatttta aattgtccaa gtctaccttt taggtctata
    14881 gtcactccac cgcctttgat gtcaactata ataccttcat aaaaagtctc tgatgagata
    14941 tattttaacc tatccattat aattctacct ctctatactg ttttaaactt ggatctaaat
    15001 ttatgttatt gtctaaatct tagttagtat ctaaatttta gttttcgtct ttttcgtata
    15061 tttctcttct cttcttactc attggtagag attgctcatt ctcttctaat actatttttt
    15121 ctcctgtaac tttttctata gcttctatgt tatttaattt aacatttgga ttccattttc
    15181 tttcaggagc tttaacttct acaccttcta tagcattttt aagcatagcc attattctaa
    15241 cagcatcttc tggagctaaa gtgttgttag ataatatttc attctctata ccttgcttag
    15301 acttattgtt gtctaccatg tgagtcatgt atttattacc aacaactaga gcaccttgaa
    15361 cagctgagaa acttacacca actactggta tacctctcat acctatttgc tctatgtgag
    15421 atgcgaaatc tatatggttg tttccgaaac cttcagtagt tactacagct ccatcaactt
    15481 ccatagcttc aactaacata cctaatctct tagatacata gaatttctca gcatttactt
    15541 gtggagaacc aacaaataca acacctacta aatctatttc ttcgtcttcc atagctctta
    15601 ttactaatgg ctctctccag taatgtcttg acatttcttt tgatgcaggt cctatacaag
    15661 ttaatgcatg gataccacca tctaatactt caagtggaga taatacaact ggcatgtttc
    15721 ctaagtcaac gtttggttga gctcctaatg taccaactgg ctcaactggt aatattaggt
    15781 tatcatgcat tgcaccttgt cccattattt cttttataac aacaactttc tttttacctt
    15841 ctcttctgta ttgctctatt acttcttcat caactactaa agagttgtca actttcttta
    15901 atgcttctct tatttcttga gttacatagt caaatgcacg gtgagcagct aaaggtcctg
    15961 gtctttccat gttagttcct gcttttattg ttacttgacc tttgatgaat atttcacctt
    16021 tgtcagcagc acctggtcta ccccacatta tagtagtatt taactcacct tctgaagaac
    16081 caaattcacc tatttgaact ccatcttcat ctgtaccagt taataccatt acagctccat
    16141 ctataactct agttatacct gaacctaatt cgccttcttc tttagtagcg attggttgta
    16201 tatctaatac agcttcactg taagtttcat atttatcagg agttattatt tctaacttca
    16261 tatctacaac taactcttga gtttcattag cttctttaca tatttcttct gcgtttctga
    16321 tgtataaagt agttccttct attttagttt catcagcaaa ttcaacttta tctattttaa
    16381 agtgtttttt agttaagctt cttaaaagtt tcttttcttc aacttttgga gctacttctg
    16441 ctgctgcact tgccactgga gcagcaacgt ttgctactgg agcagcaact cctgcttgac
    16501 cagctactga taaaggtatc tctaagctta tgttcttacc ttcacctatg tgtattttaa
    16561 ctgtttcacc tgcaactcct gtgcttactg gaactactgc tgcttctgat actggagctg
    16621 cttcttctac tgtttcttct actacttctt ctttagcctc tcctgctttg tatccttcta
    16681 cgttatctgt agtcattgga gaaagtgcat ctaaagtttc ttttaactta gctcctagta
    16741 cttgacctat agttaatcca ttttctggta ttgttaataa tccagaatcc tctaagtctg
    16801 caaatattgc tggatcttct aagttttctg gcgctataat tgttcccgct tcaaatctac
    16861 aacaacaaac tgctgggtca tttgcatggg cttgagctgt ttctaaagtt attgacatag
    16921 tataaaatac ctccttacat tattttctta tttattattt taaatctcaa ttcctcaaca
    16981 ggtaacccct taactgagaa attaagtaaa ttaaaaccta cataatttgt tatgattaat
    17041 attatttttt tctcacttaa agtcacttta tattataagc aattcctatg ccaacttatt
    17101 aacaaaaaga ttttttctat aatagattct tcatctatcg ctatttttag ccaaatatta
    17161 tataaatatt tatttaaaat atgttatttt ttgtatttgt aaacattttc tcaaacaaaa
    17221 aaagtgtcaa ttaatcaaca ctttttcatt ttttttaaca catctatata cacaacactt
    17281 atataagcgt tggctttact aggttttaaa ttaaagttta tcattttgtc aaaatttagt
    17341 catgtgtcat attttagaca catctatttt gtattggtct atcttataat acaaagttgt
    17401 tctgggtata tttaatatct tagctgcttt agctttattt ccattagaca ttttaagtgc
    17461 cttggttata ttctttattt caattttttg agttgccttc gttaaatcta aaggatactc
    17521 ttcttcttca gtactattat ttgtagaatc catcatataa cttggtacat catccacatc
    17581 tattttagaa ttttgtgaca atacaacaat attttcaatc gtatttttta attctctaat
    17641 attacctttc catctataat tctgaaatat atctattaca tctttgctaa ttgtaagaac
    17701 aggcttatta ttttgtttac atatctcctc taaaaagcta tgaaccaata atcctatgtc
    17761 ttcttttctc tctctaagtg gaggaatctt tatttcaaca acatttaatc tatagtataa
    17821 atcttctcta aatttttctg cctttaccat tttactcaaa tctttattgg tagctgatat
    17881 tattctagga tttattttta ttgtggtatc tccaccaact cttcttattt ctttttcctg
    17941 taatactcta agcaactttg cttgcatact aagaggtaaa tcggcaattt catctaaaaa
    18001 tacagttcca tcttttgcaa gttcaaatat acctattcga ccctttttac ttgctcctgt
    18061 aaacgcacct gattcatacc caaaaaactc actttcaaat aactcatttg gtatggcact
    18121 acagttaaca ggtataaatt gaccttttct ctcactataa tcatgaatag ctcttgcaaa
    18181 tacttcttta cctgtaccac tttcgcccca aataaatatg ctactatttg ttctagccac
    18241 ttgttttgca atcgctttcg atttttccaa tttataactt ttacctaaaa tcttatcaaa
    18301 actaccttta gataaatttt tgacttcgtt ctttagatat tttaatgtat catttacttt
    18361 ttcaagttca agagctaata tcttagcttc tgtaacatca acttctgtac atacaacacc
    18421 gataaattct tctttataaa atataggatt tgcatgaact aatgcataca tattttcttt
    18481 tttatctgta aaatacaagt cactcattcc aactttacta tttagtactt tttctgaaat
    18541 agtattttcc aaaaattcat tcatcggtcg accaactata tcttcagact ttatatcata
    18601 cctttcctcc ataaacttat tccacaagat aacaacacct tcgttattta tagcacaaat
    18661 tccttcttta atttgaccta taatatactt caaagttaat ccataatctt ctaaatgcat
    18721 atatagatag tccctaatgt gctcttgttt tagaactcca ataattttat tatctctaag
    18781 aacaggaaga atccctatat tttttaatat cattatatct ctacattcat ctaaggttaa
    18841 accttcgttg acatatatta catccttctt cattataagt tttactggtt gaccttcata
    18901 ctttttatgc atctcataaa gattatgtat atccgtcatg gatataatgc cttttaattg
    18961 gtcagatgaa tctattacca ttagagtttt tgtgttgctt tttatcattt cttttattgc
    19021 atcttcaatt cttgtgtctt cgtctatagt tgtaaatttt gtatccatta cctcttctac
    19081 tttttttact tctggtatcg aaaacataaa gtcccccctt tatagtagta cctcatcaaa
    19141 acttattta
//
LOCUS       DAEHWO010000082        18621 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEHWO010000082 DAEHWO010000000
VERSION     DAEHWO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.082"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            277..1263
                     /locus_tag="KNP54_003178"
     CDS             277..1263
                     /locus_tag="KNP54_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBF0894043.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1432..1580
                     /locus_tag="KNP54_003179"
                     /pseudo
     CDS             1432..1580
                     /locus_tag="KNP54_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1599..3080
                     /locus_tag="KNP54_003180"
     CDS             1599..3080
                     /locus_tag="KNP54_003180"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBF0894044.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGAIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3106..4077
                     /locus_tag="KNP54_003181"
     CDS             3106..4077
                     /locus_tag="KNP54_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBF0894045.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4333..4935)
                     /locus_tag="KNP54_003182"
     CDS             complement(4333..4935)
                     /locus_tag="KNP54_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBF0894046.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPTLWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDNSIEVDNC"
     gene            5216..6427
                     /locus_tag="KNP54_003183"
     CDS             5216..6427
                     /locus_tag="KNP54_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBF0894047.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKYNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6495..6692
                     /locus_tag="KNP54_003184"
     CDS             6495..6692
                     /locus_tag="KNP54_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBF0894048.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILSLYIKQLGVTDVSLI
                     QQYSGIVFGCTFVVAAFFSPI"
     gene            6726..7697
                     /locus_tag="KNP54_003185"
     CDS             6726..7697
                     /locus_tag="KNP54_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0894049.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7884..8261
                     /locus_tag="KNP54_003186"
     CDS             7884..8261
                     /locus_tag="KNP54_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0894050.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            8792..9451
                     /locus_tag="KNP54_003187"
     CDS             8792..9451
                     /locus_tag="KNP54_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBF0894051.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
     gene            9745..10086
                     /locus_tag="KNP54_003188"
     CDS             9745..10086
                     /locus_tag="KNP54_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBF0894052.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            10237..10650
                     /locus_tag="KNP54_003189"
     CDS             10237..10650
                     /locus_tag="KNP54_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBF0894053.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            10852..11493
                     /locus_tag="KNP54_003190"
     CDS             10852..11493
                     /locus_tag="KNP54_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBF0894054.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            11517..12770
                     /locus_tag="KNP54_003191"
     CDS             11517..12770
                     /locus_tag="KNP54_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBF0894055.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLNTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            12816..13466
                     /locus_tag="KNP54_003192"
     CDS             12816..13466
                     /locus_tag="KNP54_003192"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBF0894056.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            13517..14113
                     /locus_tag="KNP54_003193"
     CDS             13517..14113
                     /locus_tag="KNP54_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBF0894057.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            14126..14965
                     /locus_tag="KNP54_003194"
     CDS             14126..14965
                     /locus_tag="KNP54_003194"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBF0894058.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            15210..16364
                     /locus_tag="KNP54_003195"
     CDS             15210..16364
                     /locus_tag="KNP54_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBF0894059.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            16670..18367
                     /gene="ade"
                     /locus_tag="KNP54_003196"
     CDS             16670..18367
                     /gene="ade"
                     /locus_tag="KNP54_003196"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBF0894060.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMEVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT         7572 a         1831 c         3065 g         6153 t
ORIGIN      
        1 tatcgataag gctatggttg taaaaatcat agccttattt ttatattata aataaattag
       61 agtatttatc aattcatagt agataaaatt gaaattaaat ataacaacaa aaaatgaaaa
      121 ttacaattaa tttaatgtta aagactcaat tatttggatg tggaatggat agtacaagta
      181 gtatataaaa agtattgact ggacaaataa ctatatttta ttttaaatat ataatataat
      241 gtaataaaat atatcaaatg tagaaggtga taacctatga aaaaaataac aataaatgat
      301 attgctaact tggcaggagt atctaaaagt actgtatcaa gatatctaaa taataaagat
      361 atcagtgatt ctactaaaga gaaaataaag acaataatag atgaatatgg atatgagccg
      421 aatgcatttg ctcaaagttt gagagctaaa aaaacatact ttattggtat tataacaccg
      481 tgtttagatt cttttgtaaa atctaaaatt atgatggcaa tagatgaaga actcaaagaa
      541 ttaaaatata catcactaat tattaatact aatagaaaaa taaggtcaga aatagatagt
      601 atatcaaaat tagctagtct aaaagttgat ggaataatac taattggtac cgaaataact
      661 aaagaacata agaatgaaat tgaaaagtta gatataccga tagttgtagt tggacaaaaa
      721 gttgatggta tcaatagcat agtgaatgat gattatggag caggatataa aatgggtcaa
      781 tatattgcta ataaaggtta caaaaacatt gtatatttag gtgttgatga aagtgatata
      841 tcagttggtt taaatagaaa aaatggagta cttaatgggt taaaagataa agggtatgat
      901 gcaaaagtat tttatactga ctttgaccaa gaaacgtcta tacaaagaag tggagaaatg
      961 ctagaaagtg aaaatccaga tataataata tgtgcaactg ataatatagc aatagcaaca
     1021 atgaaagaaa tcaataagag aggtaaaaat ataccacaag atatatctgt agctggattt
     1081 gggggatatg atgtattgtc tattataagc cctaaactta caacaataaa gtttgaaaat
     1141 aaaaatgcag gtaaagtagc agcaaatacg atagtaaatt taatacaaga aagaaaagaa
     1201 ccactattaa aggagattaa atttgaatta atagaaggtg aaagtacaat aaataaaaat
     1261 taagatacac attacatata ttagtaatgt gtattttttt actaaaaaaa ctataattct
     1321 aaaaattagg aaaacttttt tgaaagaaat attgcatctg aaataaattt atgctaatct
     1381 ttaattaaac cggtttcgaa accggtttaa ttaaaccgat agaatagcaa aatgagtgca
     1441 aaaataactg attgtaacaa agtatcaaag taattattag agtacatagg aataaacaaa
     1501 atataaaaga tgtagcacat tgtgtaataa gactaagaat tgttttagat agcaataata
     1561 aagcaaatat aaaattataa aagaaaagga ataaaaatat gtacaaagag cctaaatata
     1621 gaaccatatt agaatcgaca aaagaagaat taaataaatt aagaaatata tctttaaatg
     1681 ataaatataa accactattt catatacatc cacaacatgg actacttaat gacccaaatg
     1741 gattagcata ttataatggt aagtatcatg tattttatca atggtatcca tatgatgcaa
     1801 ctcatggaat gaagcattgg gcttatgtaa gttctgatga ttttgtaaac tggaatagag
     1861 aagatgtagc attaatacca atcgaaagtt atgaatctca tggagcatat tcaggtaatg
     1921 cgatagaggt agatggaaaa ttgcatatgt attatacagg gaatataaaa tatagtgcag
     1981 aagatagata tgcatatcaa aacttagcta taatgaacaa ggatggtaaa ataactaaat
     2041 atgaaaataa tccaatagta agtgaaatac caaaaggata tacaggacat gtaagagacc
     2101 caaaagtatt taaaagaaag gataaatact ttatgttact tggagcacaa acaagtgata
     2161 aaaaaggagc tataatagta tatgaatcta aaaactctat agattggaat tttaaaggag
     2221 aattaaatgt aaaaaatata gatgaagatt ttggttacat gtgggaatgt ccagattata
     2281 ttaatataga tgaaaaagat atattaatat tttcaccaca aggagtagaa cctaaaggat
     2341 ttgattatca aaatatatat aatgtagtat atgctattgg taatatggat ttagataatt
     2401 taacatttga aatagataca atgaaagaac tggaaaaagg atttgatttc tatgctccac
     2461 aaacatttat aaaggactca caaataatac tatttgcatg ggctggaatg ggagaagttt
     2521 tataccctac agataaaaac aaatgggcac attgtctaac tgttccaaga aaattaaata
     2581 taaaaaataa taagctattg caaatgccag tagatgaatt aattaaatta agatatgatg
     2641 aaacaagtgg gcaaaatact ataaagaata atattaatat tatagaaaat gatgaaaatg
     2701 tatatgagct taatattaat ataaaaaata ttgacagcaa taaatttggg ctggaattat
     2761 tttcatcaca agatgaaggt gtaaaattag aatttaacaa attaggaaac attgtaactt
     2821 tagacagaag caactttaaa aaagttttcg gtgttgaata tggaacaaat agaaaagaat
     2881 atataaatat tgatgaaaat actaatatca aagtactagc ggatagaagt attttagaaa
     2941 tttttataaa tgaaggagaa gtagtattta ctagtagaat atttgctaaa gaaaattcta
     3001 atcaaataag ggtttatagt gataaaatag tagagtatga gtatactaaa tttaaattaa
     3061 agcaaggtat tgaattataa aaacacatta taaggggtag aaaagatgaa aaaagtaatt
     3121 agcataggag aagctttaat agactttata ccgaatcaaa atggtggtaa attaaaaaat
     3181 gtatcagaat ttagaagagt agcaggagga gctccagcaa atgttagtgc tgttgtagca
     3241 aagcttggag gaaaatcgag ttttatatct aagttaggaa aagatgcatt tggtgattat
     3301 ataatagatg tattaaatga agtaaatgta aatactgatt atgtattgag aacaagtaaa
     3361 gcaaatacag gacttgcttt tgtatcatta aaagaagatg gtaatcgtga tttctcattt
     3421 tatagaaatc caagtgcaga tatgctttta gaagctgatg aagttaaaaa agagtggttt
     3481 aataattgtc atatcctaca tttttgttca gtagatttaa tagatagtcc aatgaaatta
     3541 gcacataaaa aagcaataga atacgcactt gaaagtaata gtataataag ctttgaccct
     3601 aatataagat tacctttatg ggatagtgag caatcttgta aaaaggcaat atcagaattt
     3661 ttaccttttg ctcatattgt taagatatct gatgaagaat tagaatttat aacaggagaa
     3721 aatgatatag aaaaatcatt acataaactc tttgtgggga atgttgaact agtattatat
     3781 acaaaaggaa aagatggagt agatgcatac actaaaaaag taaaaggtat gtgtaaaggg
     3841 gttaaagtaa atgcaataga tacaaccgga gcaggagatt cttatatagg ttcattttta
     3901 tacaccttat tgtataaaca aataacattg aatgatataa aagaaatgaa acaagaaacg
     3961 ttaaatgagt atttagaatt ttctaattat tatgcagctc gtagtacaac tattaaaggt
     4021 gcgataagtt catatgcaac aaaggaagaa ataactgaat ttataaaaaa tttatagtag
     4081 gaatgagtaa taggttttga aggaagtaac atgtaaagag tttttaagga tgtttactat
     4141 gaaaataatt aacatataaa aagcaataaa gaggctgtct caaaatagag ataagcctct
     4201 ttatcattgt tgaaatgata aaaaatattt taattattgt tactttttag aagaatatat
     4261 atcttatttt aaataagcaa attatgtaag atttatttat attatcaata ctttacttgg
     4321 agtattatgt ctttagcagt tatctacttc aattgaatta tctaaaatat aataaatttg
     4381 ttttgcaaat tgacgagaat gttcttcttt ttctttattc ataaaattag gtttacctaa
     4441 atcacgttca acaagcattc ctatatattt taactgtgaa tgcttacagt agcgcttcat
     4501 accattttcc caaatatcag cacccttttc aggtctatat ccacatgttg taataagtgc
     4561 tactggtttt cctgcccata gagtggggcc tttctcatta ccatagtatt tattcattcc
     4621 atacaccaat ctatcaagta gtgctttcat tggagaagtg cagtaccaag aataaattgg
     4681 agtagcaaaa acaattaaat cacacataag aattttcttg aaaattttct gaacatcatc
     4741 tttacaataa catccaaaat caaataagtt atcctgacat tttttacaag caatacatgg
     4801 ctctatttta caatcatata accatattac ttcaatattt gaattataat tttctaattc
     4861 ctcaataaaa ggttttaaaa tagcagcagt attacctttt ttcttaggac ttcccataag
     4921 aatgcatact tccatattga tacctccaca gtattttaaa atagttttta gtgcttaata
     4981 tagttttagg atactatgag aatacgttaa caacaataca ctttgtatat ttgtaataaa
     5041 attgaaacaa attgttttat caataaaagt tggaatgtat ctataattaa aaatatttta
     5101 ggtatgtttt tacatatatg tgtgtagtta actatggtaa tttattgtaa aattatctta
     5161 taggattata attgcttaat ttatgattat atttaaaatc ttggaggtaa aaaatatgta
     5221 ctcaaatgaa gactataaat ttatagaaga aaatgcacca tgttatatat atgatgagac
     5281 taatataatt gaaaaatgta aggaattgaa aaataatatt ttaggttttg attttttata
     5341 ttctataaaa acaaatccat ataacaaaat tgtaaaaagc attgcagagc aaggttttgg
     5401 agcagatgct tcttcaacta atgaagttat gatttcatca gaatgtggag tttctaaaga
     5461 tgatatttat tattcatcac caggcaaaac agagattgat atagaaactg ttttagataa
     5521 atgcataatt attgcagata gtattacaga aatagaactt ataaataaga tatctaaaaa
     5581 gtataatcag aaagttaaaa taggaataag aataaatcct gattttacta tggatgatga
     5641 tagtgctaaa tcaagcaaat ttggtataga tatagaagat atgagcagtg tttttaagat
     5701 gttaagtatg tgtgattatg tatctgtagt tgggattcat atacatatta aatctcaggt
     5761 attggatttt gaaaagttag gacattatta tgaaaaatgt ttttttatag ctttaaattt
     5821 aaataaaagt aagtatatta atattgaatt tataaatttt ggtagtggac ttggagtagc
     5881 ttatgataat cttagagaaa atccacttaa tcttaaagag ctttcaaaat taactcaaaa
     5941 gattgctttt actaattcaa acacactaaa atcaagactt cttattgaat caggacgttt
     6001 catagtttgt aaatcaggta attattatgt taaaattgta gatattaaag tatcaagagg
     6061 gaaaaaatat cttattgtaa aaaatggact taatggattt atgagaccta ttatttctaa
     6121 tttaattgaa aatattactt gtggagtaga attagaaggt caagagccat tatatacatc
     6181 aaatcatgcc ttttctcttt cagtattaaa taatttaaaa gaagaagagt atgtaaatgt
     6241 tgttgggaat ctctgtacat cattagatgt aattgcaaat aatgttaaat tgaaaaaagc
     6301 aaacatagga gatttgattt caattagtaa tgctggaagt tactcctatt ctttatcacc
     6361 gctattattt tcaagttatg aatttcctaa acaatattat aaaagaaaag atggatatat
     6421 tgagtaaaca atagcataaa ttaataaact tagtattatt gaaaaaattt aaaatgcagg
     6481 gggtgtaatt ctatatggaa ttgtggaaaa gaaatttatt tgtatgttgg ataggtatgt
     6541 tttttagttc tatagggatg agccaaatag cacctatact ttcattatat attaaacagt
     6601 tgggggtaac tgatgttagt ttaatacaac agtattcagg tatagttttt ggatgtacct
     6661 ttgtagtagc agcattcttt tcgccaattt gagggaaagc tgctgataaa tatggaagaa
     6721 aatcaatgct tttacgtgca agtattggga tgggaatagt tatatttacc atggcgtttg
     6781 ttcaaaatgt ctatcagtta ttaggattaa gaatacttca aggagttttt acgggttatg
     6841 ctactgcatg tactactctt attgcaacac agacagataa aaatcattca ggatgggctt
     6901 tgggtactct tgcaactgca tcaactactg gctcattaat tggtccaaca gtaggaggat
     6961 atatagaatc aatcttaggt cttaaaagta catttattat aacaggagga ttgttgtttg
     7021 tatcatttat catctctatt ttatttgtag tagataattt taaacctaaa gaaataaaag
     7081 aatcaatttc tatacctaaa gaacaattaa atatattgcc aaataaattt ttaattgcat
     7141 ctatttttgt aaccacattc attactcaac tagctttata ctctatagaa ccaattgtaa
     7201 ccatatatat atcacaactt acaaattttg catcaaatgt agctttaata gctggattga
     7261 cattttctgc atcaggatta gcaaatttat tagcagctca aaaacttgga aaaatgtcgg
     7321 ataaaatagg tcctcaaaaa gtattgttaa tttcactttt atgggctggg attatattta
     7381 taccacaagc ttttgtaaaa actgcatggc aactgatgtt gttgagattt ttattagggt
     7441 tgtcagttgc agggcttaat ccttctgtta acagcttgct taaaaaaatt gcaccagaag
     7501 aatatgtggg aaaaatattt ggatataatg catctgccca gtatataggc tgttcatcag
     7561 gagcattttt agggggacaa atatcagcac atttaggtat tagaacagta tttttttcaa
     7621 caagtttatt gttgtttatg aatgcacttt ggatgtataa atttactgga ttgtttatta
     7681 aagataagac taaataatca tactatttac atttctaatt ttatgatgta aaataaatat
     7741 tttttatgta atttatcata gaattatata aaaaataacc ctatggtaaa aattggaaaa
     7801 tattattatc gacaaaatct ttgacttaaa aactatattg cgatagtatt aatttaataa
     7861 aagtttgaga ggggcgtaag gttatgacaa tttcaaaaat accacaagca gaattaaaag
     7921 ttatgaagtt tatttgggaa aaaaatgata cagtaacatc aaaagaaact attgaagcta
     7981 tggaacgaaa atatggttgg aaacaaacaa ctacattgac acttttatca agacttgtta
     8041 aaaaacattt tttaagtgca gaaaaaatag atagatacac tcattataca atagttgttg
     8101 gacataagga gtatttaagt gttgagacaa aagatttttt aagcaatata cacgacaatt
     8161 ctttacagag tttaatttca gcactacatg atgatgaagt tgttgataaa gatatgttgg
     8221 atttatttga aagtcatttt aaaaatttag aagaagagta attatatcag gatagaactc
     8281 taagaattta attaatctat ggctgaaaac cataaatggt attatttaat cagctactca
     8341 ctattcataa agtaatatta aataggttct ctaattagta aaatgcctaa aataattgga
     8401 atagggagta tcaagttaaa tgataccact tatttaaata agaaatgatt tttaaaattt
     8461 aaaataattt tataacttgt caatattcat taatctaaag tattatttct atttaaccat
     8521 atcaaaatat attttactat ttttaattat tacaatataa acctgtcttt tgttattata
     8581 ggtaaactaa aagtaagaaa tgatttttat atttttaaac tttattattg gtaacttatc
     8641 tgtaaatatt ttaaaatgta ctatagaaag ttgttaaaaa tattaaataa ttatattaaa
     8701 tttaagtgtg ttttttatgc tataattagt atgtattttt tatgatatat tttataaaaa
     8761 atataattta atcatttttg aggatattat tatgttagat gcatttataa caattgtttc
     8821 ttctattata gaaatatggt catgtaaaaa agtttttgat tatactagtc agtcaaagac
     8881 cgacttaaaa aaactaaata tgtattttct cttttctgtt tttctcatta tttcttcttt
     8941 atatataaat ataggagcta atagtagaat cttgatatgt atatttgtaa tgttcgtttt
     9001 ctataagtct aactataagg ttaatatata taaatgtctg gtaatctcat ttttttattg
     9061 gttaatatta ataggtataa atggattaag tatgttatta gtagcaacag taagcaattt
     9121 ggataatatg aatgttttac ttagtggcag tttatataga tatgaagcaa tattcttggg
     9181 aaagataatg ttaggtatat tactttatgt ttataaggct tcttttaaaa attttaaaat
     9241 aagtaaaaaa gagatataca tatgtattcc tatgatagca aatttattgt cattttttgt
     9301 actttatgat tatattatta atcttgtaaa aatctctcct gaaagaagaa ctgctttttt
     9361 agtaatagtt ttactattaa tattatctaa catttcaatc tttgtattaa tacatataat
     9421 acttaagatt aaaattagga aaataagata aattttaata cgattcattt aaattaaaag
     9481 ttaataatta cttttttatg tataatttta catgaatttc tataaaagtt attttattaa
     9541 agatagatat acttatatat acggatataa ttaaaaaaag tctttttaac tttaaaaatt
     9601 aatgttaaaa aataaactta tacattaata ttaataataa ttatttaaat atcttaagta
     9661 aatcagtctt acatatattt ccgatagatt atattgataa aaaacactaa aattaaatta
     9721 ataaaagtac ttggagggat ggaaatgaaa gaggaaaatt ttattaatgt tgaatacgag
     9781 gataaacgtt tttcaattaa tagtaaagaa gttttgtaca tagaaaagca agagtatgaa
     9841 gtaaagattt atactgaaag tggtaattat gaagttggag aaaatgctcc ttgtataaga
     9901 aaactattga aagaagaaaa ttttttcaaa tgcagtaata gttatattgt aaatctagac
     9961 aagtgtgaat tttatctcag caataattgt atttttgtga ataataattt tataagaatt
    10021 ttaggttcag aaagaaaaaa gaaattaaaa aagaaattag aaaaattata tgattatgaa
    10081 gattaatatt gggaggctgt attttataca gcctctttat ttattgattg tattattaat
    10141 aaattttaaa ttatgataaa atataaaaca agtaacttat ttcagaataa aatacttttt
    10201 aaaagaaagg gacgagatat gggagattat aataaaatgc ttgaattaaa gaataactta
    10261 ggtatcagtg aaagaaagtt aaaatatcct tgtatctata aacatttcaa agggaaatat
    10321 tatgctacaa tgggtcttag caaggctatt gatgatatag aaaacatatg tgaaatatat
    10381 ggtaaagaaa atttaatcca aaacagaaat aaatataaat tagttattag acatactgaa
    10441 agagaagaag atatctatgt ttatagggat ttagatggaa acttttatca taaaaaagaa
    10501 gaagatacta atgatttagt tttatacaag accttatatg atgatacagg aatatttgca
    10561 agacctttgg atatgttttt agaaaaagta gatacagata agtatgtcaa ttcaattcaa
    10621 gaatacagat ttgaagaagt atataaataa tataagagaa atatgtttat aaatttagaa
    10681 aaattcttta acagtacaat aatttgcaga aatacaaatg agatttattg taaataatat
    10741 gttagattag attataaaat agaaacaaag taaagtatta tatgatataa ttaagttttg
    10801 agaagtgata atttatattt aataaaaaat aggcatatat taggaggaca tatgggaaat
    10861 actttttata tagtaagaca tggacaaacg gattggaata tattgggaaa aacacaaggt
    10921 catggtaatt ctgaccttac gcctcaaggt atagaacagg caaaagaact ttctgaagat
    10981 attggcaagt attcaattga ttatattttt agtagcgacc ttgggagagc aatgcaaaca
    11041 gctcaaattt taggagataa gctcaatatt gaagttcaaa aaactgaggc acttagagaa
    11101 atgggattcg gagtttggga aggcctttta ataaaagaaa ttcaaaaaga ttattcagat
    11161 atatatgcaa catggagaaa tgaaccacac ttagtaaata taccagaagg cgaaactctt
    11221 aagattataa aggaaagagt agatgctttt ataaaggaac taaatgaaaa atatgataat
    11281 aaaaatataa ttcttgttac acattcaatt acattgaggg ttatgttgtt gtcattttta
    11341 gaatcaggta tggaaaatat atatagaatt aagcaagata atactgcttt aaatatagta
    11401 gaatttaaag attatgggcc tgttatagta aaaatgaatg atacaagtca tataaaaaat
    11461 catgtaaaga taaataattc tgcactggag taggaatcaa ttataaggag aaatttatga
    11521 gtaaagttat agtagttggt ggaggagctt ctggaatgat ggcagctttg tcagcttcaa
    11581 aaaacaataa tgaagtaata ttagttgaga gaaatggaga attaggaaga aaacttaggg
    11641 caactggtgg cggtagatgc aattttacca ataatagaga gatagaagat ttttttgata
    11701 aagttgtcag taataaaaaa tttctctata gtagttttta tacatttaca aataaagacc
    11761 ttatttcgta ttttgaaagt agaaatttgg aatataagat tgaagaagaa aatgaccaca
    11821 aagtatacac taaaaatgat aaatctatag aagtaataga agtattaaat aaagatttac
    11881 tcaatcacaa tgtaaagata atgtataata agaaagttat agatattata actgaagaaa
    11941 ttgctctaaa agatgattct aataaggaca agtcaaagta tctaataaaa gggattattt
    12001 tagataatgg agataaaata ctaggagaca aggttattat atcaactgga ggagtgagtt
    12061 attcaaagac gggttcagat ggttcaatgt ataagattct taaaaagcat ggacatacat
    12121 taaacaaact atatcctgct ttagttccac ttacaataga ggaaaaatgg attaaagatt
    12181 tacaaggaat atccatgaag aatgtggaaa tatcttgtaa gattaagaaa aggaaaatat
    12241 caaaatctgg agacatgcta tttgcccatt ttgggataac aggaccttgt gttcttataa
    12301 tgtcttctta tattaacaag attattgaaa aggaaaaggt agaattaaat atagatttct
    12361 taccaaattt aaatactgat gaaatctcta gtataatcag agcatttcca aataaaaatg
    12421 ttctaaataa tcttaagcaa atactacctc aaaatttctt aaaagagatt ttttctctat
    12481 tatctttagt tgataaaaag gcaagtgatt tgtctaaggc agatgaaatt agaattattg
    12541 agtatataaa aaatatgaag ctaacttgta atgggactac aggtataaac actggtatgg
    12601 ttacttctgg tggtatttca gttaaagaaa ttaattcttc tactatggaa tctaaattag
    12661 ttaagaactt attttttaca ggtgaagtaa ttgatataga tgcagaaact ggtggatata
    12721 atttacaaat agcattttca actggatatc ttgcgggtat aagtgtataa atataatttt
    12781 ttaataatta aatatgaata aatagaggtg tatatatggg taatttagtt atagctgtag
    12841 atggtccagc aggagctgga aaaagtacaa tagccaagat agtagcaaaa aagctaaata
    12901 taaattatat agatacaggt gctatgtaca gagcagttac ttataagtgt ttaaaaagtg
    12961 gtattgatgt caataatgaa aaagaagtta ttcaaatagc tgaaaattcg gatatagatt
    13021 ttaaagataa caatatatat ttggacaaag aagttataaa tgaagaaata agaacaatag
    13081 aagtaagcaa taatgtttct aatgtagcaa aaataaaaga agtaagacag ttgatggttg
    13141 aagttcaacg aaaaatagga atgaaaaatt cagtaatact agatggtaga gatataggtt
    13201 catatgtttt cccagatgca gattacaaat tctttttagt agctactcca gaagaaagag
    13261 gaaatagacg ctataaagaa ctttgtaata aaggatataa tactacttta gaagaagtaa
    13321 ttgaggatat aataagacga gatgaaattg attcaaatag agaatttgca ccattggtaa
    13381 aagctaatga tgcactagaa atagatacta caggaaaaac tatagaagaa gttgtagaag
    13441 aagttgtatc taaaataaat ctttagtttt ttatgcatca taatgaaaat aaatgtagtg
    13501 ttgaagggag ataaacgtga atttttatag atttgtaata aatattttta agggtttttc
    13561 taaaatattt tttaaatatg aagttatagg tgcagagaat attccagata gaggaaatat
    13621 agtaatagca tcaaatcata aatcgaatct tgaccctata ttcttggctg ctgccataga
    13681 aaatagagaa atagctgcaa ttgcaaagaa agaattgttt aaagtaaaac cattgggatt
    13741 tatattaaaa aaattgcatg ttatgcctat aaatagagaa aaaccagatg tatctacaat
    13801 aaaaactatt ttaaggtcag ttagagacgg ttatgtatta ggaatatttc cagagggtac
    13861 tagaataaaa ggagattctt ttggtaaggc taaggcaggt ctttctgtat ttacaataaa
    13921 aagtaaatct aaagttgttc cagtatcaat aatatctaaa tataaacttt ttagtaaagt
    13981 aattgtatat attggagaac caatatcatt tgaagaacat tttaaggaaa aattgagtaa
    14041 tgatgaccat gaaaggatat cacaagagat tttagaagtg ataaaacaaa attactttaa
    14101 atattcaaaa taagggggta aagttatgaa cataaaaata gcaaaaaatg ctggcttttg
    14161 ttttggagta aaaagagcaa tgaaaatggc atgggatgaa gttgaaaaaa atgattctgg
    14221 catatatgct ttaggtcctc ttattcataa caagcaagca gtagcaaaat atgaagaaaa
    14281 aggtcttaag actgtgaatg aaattgatac aataccaaat catgaaaata tgataataag
    14341 gtctcatgga gttcctgaaa atatatataa ggaagccaaa gataaaaaat taaaaattgt
    14401 ggatactaca tgtccatttg taaagaaaat acatacagta gtaagtgaat atcataataa
    14461 aggctatgaa ataatagtta ttggagatat gaagcatcca gaagttatag gtataaatgg
    14521 atggtgtgaa aattcagcta taataataaa gaccttagaa caaatggaaa atatggaatt
    14581 tgataactcc aaaagatatt gtcttgttgc acagactaca ataaatccag agttgtatat
    14641 aagtatagtt aataaactat cagataaatt agaagaaata gtatttaatg atacaatttg
    14701 ttcagctaca aaaacaagac aagaatcagc taaagagtta gctaaagaag ttgattgtat
    14761 gatagttata ggaggtaaac acagttcaaa tactcaaaag ttagtaaagg tttgtgaaga
    14821 cttagtacca acttttgcaa tagagactaa agatgaattg gatgtaaata cgcttaaaaa
    14881 atataaaaat ttgggtatta cagcaggggc atctacacct aattggataa tagaagaagt
    14941 tgtaacattc cttgaaaatt tataatttga taggtaataa aaataggtgg acattgttat
    15001 aatttatcat aatatccacc tttgatttca tattacatgt ggtaaataga taacctaata
    15061 tcaaaaagtg tgtatcttaa gatgaaaaac taagagtata agatgcgcac tttttaatat
    15121 tagaaattca aaagaaatat tgatattgat tatcaataga aaatagaata taatataatt
    15181 gttgcaaaat tagtctagga ggtaaattaa tggaaatgtt gatatccgct tctgaagagg
    15241 cgtttttaca tgtaggttct atgattggat tttttatttt gttatttgga tatattaatt
    15301 ataaaactag tggaaatttt actaatatca tatcaaaaaa cagaaaattt caacccttaa
    15361 taggtgcttt aattggagct ataccaggtt gtggcggaag tttggcaata atgccattgt
    15421 atataaatgg aaaattaagc tttggagcaa taattgcaag tttaatagct agtatgggag
    15481 atgcagcatt tgtacttatt tcatcaaata ttaaaatgta tttttttgtc actatagtta
    15541 gtacaattac aggaataata actggacaat tagtggatta ctttaaacta gaagaaaaat
    15601 tagggttaaa aaaccgtaga aaatcagata aatatgatat aagtaaaaat aaccctaaag
    15661 aaaataaaga acaacataat catgatgaaa taattttaga cactctagct aaatctcatg
    15721 gaaatacaaa tagacttgca tttataataa cacatggaaa gggatataaa atttatatag
    15781 gaattatagt aatcggtttt atatttatgt cacttgctca ctctggactt aatcttccta
    15841 taattgagaa gttacattca ttggaagaag taatagcagt gattggaata ttattttcaa
    15901 taatttatat gtggtgtttt aaaaaggtat ttaaaaattc taatcaaaaa gaggaagaaa
    15961 ataaaaagat ttctttgcga gaaatgctta tccattctgt tggagaaata tcatttgtaa
    16021 ttacatggat ttttattgca tatcttattt acgatttgat aatattaatt ttaggtggag
    16081 atgaatactt agttaaatta gtattatcaa caggtgtaat aagtgtattt ataggtgcag
    16141 gtcttggact tattccaggt tgtgggatac aaattgtgct tatgtcattt tatttgaagg
    16201 gaactatacc acttggtgca gtgatagcca actctatttc tcaagatgga gatgcacttt
    16261 tcccactttt agcaatggat aaaaaatctt ctttatgggc tatgattatt actactatac
    16321 cagcaatact tgtaggtatg atagtttatg catttttagg ttaaatataa ttatgaataa
    16381 agaagtatta aaaaaataat aaagcacata aatttattta taagaatagt gaagattaaa
    16441 tataaaaata aaaaattcaa tatgaattaa attattgctt aaatattaat gagaacatgg
    16501 gagataatat tattcctcat gttctctcta tttaattaaa ggaattatgg aacaaatttc
    16561 aagtgatact ttctatcaaa actcatatat aatatatatt aataaattaa actataatac
    16621 gtaatacagt cagtatattg atataaaaaa cttaggagga gttgtaaaaa tgggtaattt
    16681 aaaaagacag tgtgatgttt caagtggaag agaaaaagct gacattgtac taaaaaatgg
    16741 gacaatcata aatgtattta cagaagagtt aataacagga gatgtagcaa tagtaggaga
    16801 cactattgtt ggaattggcg attacaaggg caatgtagaa attgattgta gtaacaaata
    16861 tatatcacct ggctttattg atgcacatat gcatattgaa tctacaatgg taatgccaat
    16921 tgaattatcg aaaaaattat taaaatcagg tacgacaact atcatagccg acccacatga
    16981 gttggtcaat gtaaaaggag ttagtgcaat agatttttta ttagaatcga caaaagatat
    17041 accacttaat gtatatatta tggtgccttc atccgtacct gcaacaagtt ttgaaactaa
    17101 tggagttggt aaatttagtg caaaagacat ggagagttat gtaaataatc ctagaatttt
    17161 aggtttagga gaggtaatgt gttttaatga tgttataaat tctgaaaatg aaatcttgga
    17221 taaactagag ctttttaaaa ataaagttgt agatggacat gcacctaata taaatggtaa
    17281 atcacttcag acatatgtat gtgcaggaat agaaaatgac catgaatgta taacttttga
    17341 tgaagtatat gaaaaattga gagcaggatt aaaaatttta ataagagaag gaagcgcagc
    17401 aaaaaattta aagtctatag taagtggtat gctaaagcat aacttgccaa ttgaagaatt
    17461 tatgttttgc acagatgata agcacttaga tgatatagaa aaacaaggtc acataagatg
    17521 gaatataaaa tgtgcgattg atttaggtat ggaacctgtt agggctataa aagttgcaac
    17581 ttataattct gcaaaagcat atgggttaag gaaaattgga gcaataggtg cgggttataa
    17641 ggcagatatt gttgtattga atgatttaga caaaatggaa gtggatagtg tatataaaga
    17701 tggtaatttg gtaaacgaag agatgttttc taattacaat tatgagatta aagataaaga
    17761 attgcttaat acagtcaagt ttaaatatat taataaagaa aaaatacagt taaaagtaag
    17821 tgaaaaaaat tatgtaatgg agattgtacc ttatcaaatt ttgacaaata aggtatatga
    17881 atctttacca tgtgcagatg gatattttgt tccaaataaa gagtattcaa aactttgtgt
    17941 tgttgagaga catagaatga ctggaaatgt agcaattgct ccactaaaag gatttggcat
    18001 aaaaaatgga gcaattgcta ctactgtggc ccatgattct cataatatta tagttgcagg
    18061 ggataatgat gatgatattc tagtagctat aaattactta aaggaaatac aaggtggtta
    18121 tgtaattgta tcaaatggaa aagttcttgc acacctaagt cttcaagtag ctggattaat
    18181 tagtactttt acagctgaag aagtacaaga aattactgat aatatgttgg agatagcaag
    18241 aaaaatggaa gttccagagt atgtagaccc ttttattaca ctttctttta tggcacttcc
    18301 agttgttcca caaataagac ttacagattt aggtctattt gatgttgagg aatttaaatt
    18361 tatatagata gtataaaagt aataataaat gaggctttct caaaatagag ataagtctct
    18421 ttttattgtt gaaatgatga aaatatattt gatttcatac aaaaaagagc atctcatgaa
    18481 ctaaaaattt tatttttaga tatccttatt ttaattaatc tatcatttaa cattgtttta
    18541 agcatagata tcttaataaa actattttca gtctatttta acatataaat acatgaaaat
    18601 tatatattta tgaaacttta t
//
LOCUS       DAEHWO010000083        18584 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEHWO010000083 DAEHWO010000000
VERSION     DAEHWO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.083"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     regulatory      93..195
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            289..1665
                     /locus_tag="KNP54_003197"
     CDS             289..1665
                     /locus_tag="KNP54_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBF0894061.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(1779..2924)
                     /locus_tag="KNP54_003198"
     CDS             complement(1779..2924)
                     /locus_tag="KNP54_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBF0894062.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIILDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            3177..3884
                     /locus_tag="KNP54_003199"
     CDS             3177..3884
                     /locus_tag="KNP54_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894063.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            3931..5526
                     /locus_tag="KNP54_003200"
     CDS             3931..5526
                     /locus_tag="KNP54_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894064.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLMVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            5629..6711
                     /locus_tag="KNP54_003201"
     CDS             5629..6711
                     /locus_tag="KNP54_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBF0894065.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            6860..7021
                     /locus_tag="KNP54_003202"
     CDS             6860..7021
                     /locus_tag="KNP54_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBF0894066.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            7362..8630
                     /locus_tag="KNP54_003203"
     CDS             7362..8630
                     /locus_tag="KNP54_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBF0894067.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            8825..9613
                     /locus_tag="KNP54_003204"
     CDS             8825..9613
                     /locus_tag="KNP54_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBF0894068.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSIRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            9613..10062
                     /locus_tag="KNP54_003205"
     CDS             9613..10062
                     /locus_tag="KNP54_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBF0894069.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            10066..12330
                     /locus_tag="KNP54_003206"
     CDS             10066..12330
                     /locus_tag="KNP54_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBF0894070.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            12470..12781
                     /locus_tag="KNP54_003207"
     CDS             12470..12781
                     /locus_tag="KNP54_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894071.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            13067..13567
                     /locus_tag="KNP54_003208"
     CDS             13067..13567
                     /locus_tag="KNP54_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBF0894072.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            13624..14610
                     /locus_tag="KNP54_003209"
     CDS             13624..14610
                     /locus_tag="KNP54_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBF0894073.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            14660..15382
                     /locus_tag="KNP54_003210"
     CDS             14660..15382
                     /locus_tag="KNP54_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBF0894074.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            15411..17345
                     /locus_tag="KNP54_003211"
     CDS             15411..17345
                     /locus_tag="KNP54_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0894075.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            17338..>18584
                     /locus_tag="KNP54_003212"
     CDS             17338..>18584
                     /locus_tag="KNP54_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBF0894076.1"
                     /translation="MSKNIYVKETYEWIRIGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKK"
BASE COUNT         7113 a         1832 c         3166 g         6473 t
ORIGIN      
        1 tataatcgaa tattaataca aaatcaatac aatatatacg tatatattga caaaattaat
       61 tatataaatt aaaataatat tcgtaaagaa aaattcatgt tttgtactgt ataacatata
      121 attttgacaa tatgggtcat aagtttctac cggaataccg taaatattct gactatgtat
      181 actattattt agttaattaa atatttaatt aactgaatta tgaaggatac ggctcagctt
      241 atcaactact gtgtcgtttt tttgtaaaat ttaataggag gtgttgttat gcaaacaaca
      301 aacagtagta ctatgcagaa actttttcca attttgacta ataaaaatgt cgacatgaag
      361 aaggaaataa ttgcaggagt aactactttt ttaactatgg cttatataat agctgtaaat
      421 ccaaatattt tatctgagac aggcatgcct gcaggtgcac ttgttacagg tacttgttta
      481 gcagcagcat ttggatgtat tttaatgggt gtagttgcta accttccttt tgctttagca
      541 tcaggtatgg gtcttaatgc attttttgca tatacagtag ttttacaaat gggtgttcct
      601 tgggaagtag ctcttacagc agtatttgta gaaggtatta tttttatagt attatcagta
      661 agtggagttc gtgaggctgt tgtaaatgcg ataccaaaaa atatgaaatt agctgttaca
      721 ggtggtatag gaatatttat tgcacttata ggtctagtta acagtggaat tgttattgga
      781 gaccaagcca ctcttatcaa aatgggtaga tttacaccag cagtaataat aacttgtgta
      841 ggattaataa ttattgctgt attagataaa aaaagagtta aaggttctat actttttgga
      901 atagtagtga gttcattact tgcttgggca tttgctttta taaatccaga gtatgcacaa
      961 aaattaggta tatatttacc tggtggatta tttaaattcg aaagtttagc accaatagca
     1021 ggtaaaatag atttaggata tgtactacat ccaacaaata taggtggttt tttagtagta
     1081 gtttgtacat ttttatttgt tgattttttt gatacagtag gtacattagt tggtgtttgt
     1141 tctaaagcaa acatgttaga tgaaaaaggg aatgttccta atgtaggtag agccttactt
     1201 acagatgcgg ttgcaactac agttggtgca ggacttggag tatctacagt tacaacttat
     1261 gttgagagtt caacaggagt tatcgcaggt ggaagaactg gatggacagc aataacagtt
     1321 ggaattttat tcttagctgc aatgtttttc tctcctgtat ttatagcaat tccatcatgt
     1381 gctacagcac cagctttaat atatgttgga tatttaatgc ttggtacagt taaggatata
     1441 gagtttgata atataactga aggtgttcca gcttttgtta ctattgcttg tatggcatta
     1501 acatatagta taggtgatgg tttaacttta ggtatattaa cttatgtttt cgtaaatata
     1561 ttttataata tatttggagc taaaaaggca gaagacaaaa aacatgtttc tgtagtaatg
     1621 attgttctgg caatattatt tataataaaa ctttggctac tataataggt attatttaaa
     1681 attttaattt aatataaaat aaagggctgt aatttattat caattgtgat gataaactac
     1741 agctcttttg tatttgttgt atttttgtat ttattgtatt atttaataat gtctattagt
     1801 tctccatttt gtaaagtttt aggtgtaatt actatattga actctttttg caaatctttt
     1861 ataatatcta attctttttt tgttattatt gagattgtgt taccacttcg atttcctcta
     1921 gcagttcgac cacatctatg caggtattca tttttacttt ttggaaaatc caagttaaaa
     1981 acatgactta catccacaat atctagtcca cgagcagata aatcagttgt aattaaaatc
     2041 tttgctttac caagtttaaa tttatttatt gcattctttc tatcttcttt ttccatattt
     2101 ccaaaaattc ctattgcttt gtaattatga taatttagtt ttgatactag gacttctata
     2161 tttttttcat tatttacaaa tacaatagct ttttttggat ttgtagctgc taatgccttt
     2221 ctaagaaaag taaatttatc ccttatctca cctaataaat atgagtgatt gatgttagga
     2281 tttatttgtg atttttcctt tgtttttatt atttcaaact ccttcataag tttatcacaa
     2341 atttttatag tgctatcagt aagacttgca gagcatccta taatttgtct atctcttaac
     2401 gttgttctta ttatgtcttc tatacaagtt atattttttc cattcaatag attgtccact
     2461 tcatctaaga taatagtttt tatattatgt gattttagtt tcttttgttt tatcaagtct
     2521 aaaactcttc cacaagagcc aattactatg tgtggtttta ctgcttttat attttttatt
     2581 tgtttttgta tattgacctc cccaattaaa gctaaagaag taacggagag ttctgcattt
     2641 ttagccaata attcaacctg gtttgtaatc tgcattacta attcatgcgt aggtgcaagt
     2701 ataagagctt gtgtttctct ttttgatgta tcaatttttt caaatatagg taaaaggtat
     2761 gctagtgttt ttcctgttcc agtctgtgaa ttaatcaata aatccttatt ttgaattata
     2821 ttccctataa caagtgactg aacttctgtt ggagaagtta tgtcttgttt tttgagtcca
     2881 tctattagag tggaacttat ttttaattgt tcaaatgtat tcatatttta ctccttatat
     2941 tttaataatt atagtcaact attttttatt atacattgtt tattcaaatc gaactatata
     3001 ttcttttata attatgtgta atttgaaagt aaatatcaat tatatttata cctttatatt
     3061 tctgatacct ttgcatttta tagatttcta aaataaacaa ataaaagttg taattgtttg
     3121 atatttgtta tatattatat ataacaaata ttaaaactat aatatggagg gaaattatgt
     3181 taaaagtaat caatgtatct aaatcatata aaaataaaaa agtagtaagt agtgtctcat
     3241 ttgatgtaaa tgatggagag ctttttgggt ttataggaca taatggagca ggtaaaacta
     3301 ctactattaa agcaattgtt ggaatacacg attttgaaga gggagaggta ctaataaatt
     3361 ctaaatctat aaaaaaacag cctgttgaat gtaaaaagga aatggcatat atacctgata
     3421 atccagattt atacgagtca ttaactggta tacaatacct taattttata gctgacatat
     3481 ttgaagttgc caaagataaa agagaagagt taataaaata ttattcaaat aagtttgaac
     3541 tcaataaagc attaggagat ttaatatctt catattcaca tggtatgaaa caaaaattag
     3601 ctataatttc ggctttgata cacagcccaa aaatcttaat tcttgatgaa ccttttgtag
     3661 gtcttgaccc aaaagcttcc tttatattga aggaaattat gagggagttt tgtgacaaag
     3721 gtggttgtat atttttctca acacacgttt tagaagttgc tgaaaaaatt tgtgataaga
     3781 ttgccataat aaaagatgga aatataattg cttatggaac tacagaagaa gttaagggaa
     3841 gtaattcact tgaaagtatc tttatggaat taatagagaa ataaaatgtt ttttatacaa
     3901 tatagtgtct aaagtgagga atgataaaat atgagcaatc taagtatatt aataaaaact
     3961 aatataataa atgaatttaa attaaatgcg ttaaaaaaag ctgatggtag agaaaaacaa
     4021 aaaataatgg gaatgatgct ttcagttgtt ataatagcgg gtctattaat tttttatgta
     4081 acaagcttaa gtctctcttt agttgatatc ttaaagcaaa taaatcaact ggaaatgcta
     4141 ctgatatttg gttttggatt atcaacatta acaactattg ttacatcatt atataaaacg
     4201 tcatcatatc tatttcaagc aaaagattta gaccttttga ctagtttacc tataaaagaa
     4261 tctactgtac tagcaagtaa gatattaatg ttggttggag caaactattt attttcttca
     4321 atatgtatga ttatacctgc agtggtttac tttttaaatt ctgatgtaag tataacttat
     4381 ttcccttatt tgatattgct atttttagct ttaccattat taccgatagt tgcttcatca
     4441 ataatttttc tatttatagg gcagatatca tcaagaataa aatacaaaaa tttagtatta
     4501 atcataggta gcattatatt gatgttgctt tataccctac ttatgtcaag acttaattct
     4561 atgtcagttg aaatgctaaa gaatagtgtg tctatttcag agacaattag aaaagtatat
     4621 cctcctatat attattttgt tgatgctctt aaaacaggaa gtatagtttc atttttagca
     4681 tttatagcca tctcaataat accatttttt atgtttgtaa ctctatttgc aaaaaaattt
     4741 aaagatataa atgctaagat gagtgaagga tataagtcaa aaaattatga atttaagggt
     4801 caaaaaactt caagaccttc aaaagcttta ttaaaaaaag aatttaagag atatacttct
     4861 tcgtttatat actttttaaa ttcatctgca ggtttgttat ttctaatggt aggtacaatt
     4921 ttaatattat tatttggagc agataaagtg ggtgagttac tgaaattgaa tatagatttt
     4981 aatcttataa aaatacaatt attgggagta ttcttcttta taatagtaat gaattgtaca
     5041 acatactgtt caatttctct tgaaggaaaa aacttatgga tactgaaatc ttctccaata
     5101 gatgaaagag aaatattctg gtcaaaaata ttgatgaatt ttttattgaa tgcaccacta
     5161 tctattttat gtctaatatt agtatctata agattagact ttgaaattca gtttattatt
     5221 gtatcaatct gtttgattgt aagtttttca atgtttgtag cattgatggg attattatca
     5281 aatttattat acccaaacct tgattggaaa aatgaggtgg ctgtagtaaa aagaagtgca
     5341 agtatgatag ttacaatgtt agtatcatta gcttatgtaa ttatacttgg aggtatatat
     5401 gtattacttg gaatttcgtt tttaaatata tatattattt tggcaagtat acttactttg
     5461 atattagatt ttatgatatg gagaattatt tctactaaag gagtaagaat atttaaaaat
     5521 ttataggtgt atttatgtca aataaagact tatctttttt agtcttgcaa ataataggtt
     5581 aagtagtata ctatgtatag tgatatgaaa aaatttagga gaaaataaat gagaaaatta
     5641 tccaaaagag aaaaagattt tattcaatat ggatttttat tatttttgat atgtattact
     5701 acttatttag tattaactac tttagatata aaactaatac ctaaaattat aaggctagta
     5761 aataagactt atatatttct tggcatattg acaattatag tatatatgat aattgaatct
     5821 attgtaactc atttgataat aaatgcagtt caaaaaacaa aagtaaaatt tattggtatt
     5881 aaaatggcta caatgggatt ttactataac ttagttactc catttgcatc tgggagtcaa
     5941 ccaatgcaaa tatatgcact tacaaaatat gatgtaagcc ttagtaaatc agtggctata
     6001 gttactaata aaactgtagt atttcaaagt acagttactg tattttgtgg aattttaatt
     6061 ttgctaaata agtcattact gatggagcaa gtacattctg tgaaagtctt gataactttt
     6121 ggaatgatta tgaatgtaag tatgttgtta ggtggactac taatagtatt tagtccaaaa
     6181 caagtaaaaa tgatagcaga agttttgatt aattttttat ctaaatttaa aacatttaaa
     6241 tttttagatt caaaacgtga tagaataaat cattatattg atgattataa ttattctata
     6301 aaaatattta ttaaaaatgt aagaatctta gttttaagta tattacttac tgtgttacaa
     6361 ttaatcgcat atttcagtat agtttattgt gtgtataaag cctcaaattt aagaggagtt
     6421 tcatatgtac atataatgac attacaggtc tttttatata tggctatatc accaattcca
     6481 acaccaggaa atgttggagc taatgaggtt acatttttta ctatgttctc caatataatt
     6541 ccaaaagaat tattggggta ctctgtactc ttatatagtg ggtttgtata ctattttata
     6601 ttaatagttt caggtttatt tacatttgga acgcattata cattaaattc ttggaaaaag
     6661 gaaaataaag taaattctaa tttagataag gttattgaaa aattaaatta ataaaataat
     6721 tagggaaatt ctatatataa atatggtgtt gaataagcta tattatattg agatatttcc
     6781 cttttttgat taaaattata gaaatttgaa ataataagta ataaacagaa aaagtgatat
     6841 tgttttgaaa ggagaaacta tgaaacaaga taaacaaaat gaaaaacaaa gtgagatttc
     6901 taagataaaa caaagcaatg ataataaact tgaaatagct caagaattac atgtaagtaa
     6961 aaatataggg aatatgcttg gatatagaat agataagaaa aaaatgaata gaccaagtta
     7021 atgaaaatgt tgaaaatggt acattttaaa aaatatatat aatgaaatgt tttattgtta
     7081 aatttaaact tattttaatg ggggaaaaag tcgaaaaata tctaaaaaga tatggatata
     7141 aaaaatatta atatatatat actataaact tgacaaaatc aaccttttaa taactagcaa
     7201 aaaatagcaa aattatataa gcgttattta attgtcaaaa atgaaagcta aattgcatgt
     7261 cctaaaaaaa atgattgata acatttattt gtgtgctata attatatagt aaaacaataa
     7321 gtatattgca taatgtatgc aaatcgggag gagagacgga catggaagca tctatacaca
     7381 caattgccag caataattta ttgataattt ttgctattgt aagtataact ggaataattt
     7441 gtagtaagct tagtgaaata ataaaggttc cagatgtagt gttatattta cttgtaggta
     7501 ttttaatagg accatcattt ttaaaattta tagatattcg tggatttcaa atagaaaatc
     7561 aactaatact tacatttggt tctgcattta ttttatattt aggtggaaaa gaaataagtt
     7621 taaaagtatt gagaaatgtg aagatatctg tattcttatt agctacttta ggagttgtga
     7681 tatctgcttt tataatgcaa caagtaatag gatttacttt tgggataagt gcaatgactg
     7741 ctttactagc aggaactata atagcatcaa cagacccagc cactcttgta cctatattta
     7801 atcaggtaaa gataaaggat agggtaaaac aaactgtaat aagtgaatca gcttttaatg
     7861 atgcaacagg agctatacta acatcagcag tgttggctgt aattttgtca aataaatttt
     7921 cattaggtga aaatatttat gaactgggga caatggttat tgtcggagtt ttagttggtt
     7981 taattacagg aatactgctt ttgaaattag ttaatgataa accttatgga atatttaaag
     8041 attttgcacc aataatatct gttatttcag ttgtagttgc atatgaatta tctacaaaat
     8101 taggtggaag tggatatatg tcttgcttta ttgtaggtat aataactggt aacaagaaaa
     8161 attttaaaat ttggttaagt caaaaatctt atgatgcaga tttttatgtt gctgaaactt
     8221 taggtactat ttgtcgtatg gcaatattta taatattggg tagccaagtt aatttggctc
     8281 agttaagtaa atattttatg ccatctgtaa ttacagtatt agtattaatg tttatagcaa
     8341 gaccactttg cgttttagtt tgtacacttg tagacaggga agcaaaatgg agtaaaagtg
     8401 aaatattatt tatgatgtgg gtaagggaaa caggcgtaat accagcagca ctttgtggta
     8461 ttatttcagc aatgaaagtt cctggatacg aagtgatttc atctgtagta ttcatgacta
     8521 tactaattac attagtaata caaggaagta ctacaaaatt agtagctaaa aaacttggat
     8581 tattagaaga agaagtgata aatataagtg aaaaagtatc aactttttaa agttttgctt
     8641 taaaatagta cctgttaatg gctattttaa tattgtctaa tgatgattat tgaaatagtc
     8701 atttttttat gtataagtaa tttacagaat ttacatatta gacatattta ttatcaaaat
     8761 ttgttgaagc tatgatataa ttagttgtat ttaaaataag aatagcaaat aagggaggaa
     8821 atttatgttt acggttatgg atattgtaca gccagataca gtagaagaag cgtactcaat
     8881 tttaaataaa agaaaaacta accaagtaat tggtggaagt gcttttttaa gaatggggaa
     8941 aaaaagaata ggaacaggaa tagaattatc taaattaaat ttagattata taaaagagta
     9001 tgaagattac gttgagattg gttctatgac tacttttaga acattagaaa caagttccat
     9061 aataaaaaat aattttggaa gaataataga agattcagtt aaaaatataa taggagttca
     9121 gtttagaaat gtagtaacag ttggtgcaac agtattttct aaatatggtt tttctgactt
     9181 gatagtagca ttactttcat tagatacgga agtagaatta tataatattg ggagaattag
     9241 tcttgaagag tttctaaata gagattatga gaaagattta cttattaaga tatacataaa
     9301 gaagacaaat aagaatgctt cttataaatc aattagaaat gcaaagagtg attatccaat
     9361 tctaaatgta tctgtatcaa aacatatgga acaatttaag ttatgtgtag gagcaagacc
     9421 gcagaaagct acgattgcaa aacaagctag tgaatttcta tctaacaatg aaatcaatga
     9481 aattaatata gataaagcag tagaaatagc atcagaagaa ctaacttttg gttctaacat
     9541 gagagcatct agggagtata gaaaagctat gagtaaagta cttttaaaaa gagctataat
     9601 ggaggttatt taatgttagt aaagattaat ataaatggga agaaaaaaag tgttgatata
     9661 gaaccagaag aatatctggt tgatacttta agaaaagttg gtaatttaag tgtgaaaaga
     9721 ggttgtgaca caggttgttg tggtttatgt acagttttaa ttgacaagaa acctacatta
     9781 tcttgtgcaa cactgacatt gagagcttta gataaagaaa taactacaat tgaaggttta
     9841 gaaaatgaag ttaaagaatt tagtgaagtt ttggtaaaag aaggagctga gcaatgtggt
     9901 ttctgttctc ctggctttat acttactgta cttgcaatga aggatgagct tgaaaatcct
     9961 acagatgatg aaataaagca ttatcttaca ggaaatctat gtagatgtac agggtatatg
    10021 ggacagttaa gagctatcaa aacttatctg gaggtaaaat agaacatgaa tatagttgga
    10081 aaaggaatca agaaaataga tggaatgagt atcacaacag gaaagcctgt atatacagat
    10141 gatttatcag caaaagatgc tttggtggta aagatactta gaagtcctca cgcttatgca
    10201 aaaataaaag atatagatac atcaaaggca gaaatggttg atggtgttga atgtgtttta
    10261 acatataaag atgtaccaaa atctcgattt acacttgctg gtcaaacata tccagagcca
    10321 tctccatatg atagattaat tcttgaagat gttgtaagat atgtaggtga cgaagtagct
    10381 atagtggcag ctatagatga aaaaactgca attaaagcaa tgaatcttat caaagtaaag
    10441 tatgaagtac ttacacctgt tttggatttt gaagaggcaa taggaaataa aactatggta
    10501 catgatgaag atagacattg taactttgat ataggtatgc aaagagaaaa aaatatagta
    10561 tcccatcatg attatacaaa aggtgatgta gaaaaagtat taagtaattg tgatgtagtg
    10621 attgaagaaa cttattatac tcaagctcaa gcacatgcaa tgatggagac gtatagggca
    10681 tacaattatt tagaccatat gggaagattg gttgtagtaa gttcaactca aataccattt
    10741 catgtaaaaa gacatttatc tcgtgcacta gaaataccag ctagcaaaat tagggttata
    10801 aaacctagaa ttggtggcgg atttggtggt aaacaaactg catgtgttga gattttttct
    10861 gcaattgtta ctttaaaaac agggaaacca gctaaaataa tttatgatag aaaagaaact
    10921 tttaattgtt caacaagtag acatgcaatg agattaaaag ttagactagg tgctacaaat
    10981 gatggcataa taaaggcaat agatataaaa gcactttctg atacaggagc atatggagag
    11041 catgcttcta caactattgg tttggttgga gaaaaaactt taccaatgta taataaagtt
    11101 gaagcaacaa gatttattgc agatgtggta tatactaata agatgccagc aggagcactt
    11161 agagggtatg gagcatcaca aggatgtttt gctgttgaat caactataaa tatgcttgct
    11221 aataaattaa aaatggaccc aacagattta aggttaaaaa atgtggtaac agaaggtgaa
    11281 actacatttg catatggtaa aactttaaat agtgtcgatt taataaaatg tataaataaa
    11341 ggcaaagaac ttattggatg gaatgaaaaa tatccttgta aacatcttga taatggaaaa
    11401 attagaagtg tgggtatggc aattactatg caaggttctg gtatacaagg tcttgataag
    11461 tcttcagctg aaataaaatt gaatgactgt ggagattata ctcttatgat aggttctact
    11521 gatatgggta caggaagtga tacaatttta gctcaaatgg ctgctgaggt tcttgataca
    11581 agcattgaaa atataacagt tatatcagct gatactgact tagttccata tgacccaggt
    11641 tcatatgctt caagtactac ttatgtaaca ggtatggcag tagttaaggc agctcaagac
    11701 ttaagagaaa aaataatttc tgctggagca actaaactag gtgttgagaa ggatgaagta
    11761 gaatttgatg gtataaaatt aactagtaaa aaaggtagca ctttattatt cgatatagca
    11821 gttgattcta caattggtcc agatactaat caattaatag gtcttgcttc tcatggtagc
    11881 ccagtatctc ctccaccttt tatagcaggt tttgcagaaa ctgaaattga cacagaaact
    11941 ggaaaagttg atttagtaaa ttatgtagct gtagtagatt gtggaacggt tataaataaa
    12001 aatctagcta agatacaagt tgaaggtgga attgttcaag ggattggaat ggcattattt
    12061 gaagaagtta gatacacaga aaaaggaagc atggacacaa atacatttat gcaatacaag
    12121 attccagcta gatgtgatat tggaaatgtt aaagtagatt ttgttgaaac ttatgaacca
    12181 actggaccat ttggtgctaa atctgttgga gaagttgtta taaatacacc tttaccagca
    12241 atacaagaag ctgtgtttaa tggaattggt gtaagaataa atacactccc tattacacct
    12301 gaaaaagttt ttatggaaat gaataaataa ttatttatga aaatttagac tagttttaca
    12361 tgttaaacaa ccagttatgt catacctgtt gaaagatatt taataagtag ttattataat
    12421 attatgaatt ttacttataa aatacaaaat taaataaggg gatgatgttt tggctggtaa
    12481 tctaaataat atgagagcag taaataattt tagaggagat aagaacattt tagaatgttt
    12541 agtcagcttt gagggtcgtt caataagtca gagaaaagta agggtatttt ttaaagaaaa
    12601 acaaaatcaa atagaaattg attttgcaga agaggaaatt tctaaattgg ttgaaaatgt
    12661 tgttttaaat acatcatatc aagaaatgtt atatgatgaa atagagaaac aactggaaat
    12721 tgattgtata ggtacttgga tgatattatc taaattaaaa gatggtagta gagttcactg
    12781 attttaaaat aaattattag agcctaattt taaggctctt ttttgctgtt tttaattaac
    12841 aatagaaaat ttatctttag tttgtatata attttaatat catatattct atatatataa
    12901 aattgaattt gtatgtatta tattgtataa tataaaatga attgggaaaa tagttcgcta
    12961 aaataatttg tttttataaa attactgttt aagtttatag attttgtata aaataaagtt
    13021 atgttattaa tttttttaaa aataaaactt ttactaggag acagatatga gaaaaaatag
    13081 tattaatata gcactaactg cagcaattac agcaatctat gcagttttaa cattatcatt
    13141 gggatttata agttatggac caatacaatt tagggtagca gagattatga tgcttttggc
    13201 atttttagat aaaggatata tagtaggtct tacattaggt tgttttttag caaatgtaat
    13261 aggaccatat ggtgtacctg atataatttt tggaacatta gccacattta taagtgcaag
    13321 tatgatttat attactagaa agttaggtaa acaaaataaa agtactttag ttatagcttc
    13381 tttatggcca actgttataa attcgattgt ggttggtcta atgttaaatg tattctttgg
    13441 gcttccatta attctatcta tgatacaggt aggttttgga gaatttgtag tagtaacaat
    13501 tgtaggagta ccatttttct gctttttaat gaaaaaatat aaaaatgtca ttaatattaa
    13561 attttaaata gtgtatagta atttaattaa ttgagagtat tattagtgaa aagaggtgtt
    13621 tatttgtcga aggtaaaaag attgactgat gtttggatat atattaatga taagcaaaag
    13681 tttacaataa aagagttgtc agaggaattt aatctttcag ctaaaacaat acaacgatat
    13741 ttaaaagaat taaataaaat gggacttcca attcaagcag aacaaggtag aaatggaggt
    13801 tatagggtgc taaataatag ctatatacct cctgttatat ttacagaaaa agaagttatg
    13861 attatactat ttgcacttaa gtcacttcag atttataatt ataagttaat ggaaatagaa
    13921 attaattcta taatgagaaa agtaagttat gaacgtaaaa gcagtataaa agtaggtata
    13981 gaaaatatta aaagatacat tggctttgta gctaatgata ctaatgatgg agattttaag
    14041 agtagtaatg taactgagtt ttttagagct tcttcagaat ctctaatttt aaatattaag
    14101 tataagtgtg gtaatcagat tttggaaaaa aacgtatgcc ctataggtat atatttaaat
    14161 aagggagcat ggttttcacc agcatatgat tgtaaaagtg ataaaataat attagttcat
    14221 atagataata taattgatat aaaaagaaca ggagaaagta aaaaaataca tataaacttg
    14281 gaagaatggt tacatgaagt atataacaat ttatatggaa atagttcaac tactaaaaaa
    14341 tttggtgaaa ttatttatct aaatgtatta ttaactaaag aaggtgtttc taaaataaag
    14401 gacagttctt ggaatttaga tatggagcta aatgaagatg gtagtggaat aattagtaca
    14461 ttcataaagg ttgaagatat agattgttat gcttcgattt tattttttat tggaaataat
    14521 gctaaggtta tagagccaaa atttttgaat aagctacttt atgataaggc caatgagtta
    14581 agatattttt atgaagaaaa tatggtataa tatttagaaa tgttgaaatt aaataattat
    14641 taaggagata tacgttataa tggaaaattt taataagaat gctaaaataa ttggtattgg
    14701 agctgaaggt attaatataa taaatgaagt agaagaaaaa ataaaagcaa atatggatat
    14761 agaaaaaata aacataaatc aagagattga aaaagaatat gttagaagtc ttttagatgg
    14821 tgtagatata ttatttttga tatattcatc tgaagataaa catattagag atattataaa
    14881 agctgtttca tatatgtcaa acgaaagaag agttctatct ataggaatgg attgttcaga
    14941 gaaggaaaat aaagaagatt tagagcttgg gagagagttt aaaatcaata atgatagtat
    15001 atttaaattt gttgatttaa tgaatatcat ggtagagtct atttctgatt cttgcatgat
    15061 aaatatagat attactgatt taaaagaagc tattgtagga gataaaggaa ttaagtattc
    15121 ttttgaagag tttgaagata caaagtcata tagcgagata gctgacattt tatttgacag
    15181 gatggaatat attggtgagg aatttataag taagaaagga attgtatttg ttgaaggaag
    15241 tccagaattt tctataatgg aattgaatga tttaataagt aatattcaga gcaaggtaga
    15301 agaaagctat gaagtaatat tttctttata tataaaggaa aatttaaatg gaaatattag
    15361 agtaggctta ttgtataatt agtatatttt agatattaag gagagtgtat atgtctgaaa
    15421 atataagagg tacagagtat tggttaatgg aagaattttt ttatcaggaa acagacacac
    15481 cacagatttt tagagaagaa agcataattg cacttggatt tgatataaaa ataaatttaa
    15541 aaaaagtatt cagtatgggg aaaaaatcag aaaagtatat taatgagaat tgtaatgata
    15601 aagattttat aaaaaagttt atgtcgatta aaaaaggaga ttatttttta tataaagcat
    15661 atcaaaatat agaagaaaaa gttaaatgta atgtgtctat tggcatagtt gaagaagatt
    15721 ttgaaaatgg atatgaatta agtcatattt tagggcatac actaccagta aaatggatgc
    15781 ataattttga tacagtttca aattgtaaag tatatacaag tgaattttat aaattaaata
    15841 ataatgatat tagttcatat ttagaaatta ttaagtcaca agataagaaa ttattgagaa
    15901 aaagaataga agaaagtgaa aataataaat ggtatttaaa aaactattat tataaaaatg
    15961 tagataagtg tgtagatgat gaagaattat ttattcagcc cattaatcta gaacaattag
    16021 aaagcctaaa aaatataaag acagatgatt atattttatt gtataatagc gagaaagtaa
    16081 tttgtgaaaa tgaccataca atgaagagtc tatttggcgt atgtcaagtt atggaagggt
    16141 tcgataaaga gaaagtaagt gctttggagg gtggatattt ttttcctgtt agatggatag
    16201 agtatgaaaa ggagaatata gacggaaatg catgggttat atttgaaaat aatagtatag
    16261 ttgaaaagta tgtaaaaaga tttactaata aaatgccatt aaatactata ctttatggac
    16321 caccaggaac tggtaaaaca tacaatacaa aacagatggt ttacaatcta gtaagtgaaa
    16381 ccagtctaag aaacagatac tatacaggtt acttagatta taaaaataat gtagaatttt
    16441 gtacatttca tcaatcatat ggatatgagg aatttataga gggccttaag tctgatggtg
    16501 aaggcaattt taagccagaa gatgggatat taaaggatat atctatagaa gcatgttata
    16561 atgcattgaa atttgaaaaa aagatgagct ttgagttgga aaaagatagc ttgactttag
    16621 aaactataaa agacaggaaa aagaaattag tattagaaaa tatagaatat agtgagagtt
    16681 ttaattttga agaatcagaa aactatgttt taataataga tgaaattaat agagggaatg
    16741 tatctaaaat atttggtgag ctaataacat tattggaaga tgataaaaga cttactaaat
    16801 caaatcaaac tattgtcaaa ctaccatatt caaaggaaaa attttctcta cctccaaatt
    16861 tgtatatagt tggaactatg aacacatcag ataaatcaat agcactttta gatatagctt
    16921 taagaagaag gtttaatttt gaagaaatta tgccagatta tgatttattg tctattgtag
    16981 atggtataga tattagaaaa atgctatata caatcaataa aaggatagag tttttatatg
    17041 atagagacca tgttattgga caagcttatc tacttgctgt agaaaatatt aatgatatag
    17101 tagtagtatt tagaagtaaa ataataccac ttcttcaaga gtatttttat tatgattcag
    17161 aaaaagtagg tttgatttta ggaggaattg gaagaaatga aaaagataaa tacattgttt
    17221 ataaagaaaa acttatagct tctgagttat ttaaaaataa taatgcctca ataatggaga
    17281 gtaaagttaa ctattgtata aaacaaaaca tatctagtga ggagctaaaa aatatatatg
    17341 agtaaaaata tatatgttaa ggaaacctat gaatggataa ggataggtaa tggtgaaaat
    17401 gagcttacag aaattgaata tgaaaaattg cttaagtatc tagagaacaa taatgatgta
    17461 ttaaaaagta atataataga tattaaatac aaaaaactta gatttataaa ctatgtaggc
    17521 atcatatgtt ttgaaaatgt aatacttgaa atacttccta aattgtcatt aagtgataat
    17581 cttgtaaaag atagagagat actattacag atgctttcta tatgtaataa aattccaatt
    17641 acaatgaatg aaaaaataag attgagtttg aaaaattata atctcttaaa tttttttgtt
    17701 atgtatttca ttgagagtat gcaaacacag atgaaaaaag gtatttattt tgaatatata
    17761 aataaaatag agaacttaaa tgttatgagg ggtaaaatat tattaagtac atatgcaaaa
    17821 gaaaaaggca tttctccaat gaaaataaga tgtgaatatg atgagtatag tgaaaataat
    17881 ttcttgaatc aagttcttaa aaaagcatgt atatctattt tatgtagaat aaatgacaat
    17941 tcaattcaag gcaagattaa aaaaatttta agctattttc aaaatgtaga tttaatttat
    18001 atagatagaa aaaaactgtt ggattataaa ttttataaaa acaatgatag atttaaagat
    18061 tgttatttac tagctagact tctactttta aatttgtcta tggataatag tcaaaataat
    18121 caagaggcat tttctatatt atttgaaata aatactttgt atgaagaata tataggaatt
    18181 ttaatcaaaa gtatatggga caattcattt agagaaacat atatacaaga taagagtaaa
    18241 tttcttttga aaaatgaaca aactggtaag aaaaacttta atttaagacc ggatatagtt
    18301 ttatatgact taaaaaatga atatgaaatt ataattgaca ctaaatggaa agctattgaa
    18361 gtagattcaa atgtttttta taggtcaagt gatatatacc agatgtatgc atatataaca
    18421 gcatatgaaa atgcaaaaag atgtatatta ttatatcctt gtattcaaaa agataagaat
    18481 tatagttcct ggaaattatc agaatcattt aagggtaagt ttatagaagc aaaaactgtg
    18541 aggttagatg atataaaaaa cacaaaaaat gatttaaaaa agat
//
LOCUS       DAEHWO010000084        18496 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEHWO010000084 DAEHWO010000000
VERSION     DAEHWO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.084"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..252
                     /locus_tag="KNP54_003213"
     CDS             <1..252
                     /locus_tag="KNP54_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBF0894077.1"
                     /translation="NDDGVIVETRKMQGVTVLARVKSFEGLVGKNLEYIEKSDLTVYN
                     KLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            281..841
                     /gene="srlA"
                     /locus_tag="KNP54_003214"
     CDS             281..841
                     /gene="srlA"
                     /locus_tag="KNP54_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBF0894078.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            905..1273
                     /locus_tag="KNP54_003215"
     CDS             905..1273
                     /locus_tag="KNP54_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HBF0894079.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            1298..1864
                     /locus_tag="KNP54_003216"
     CDS             1298..1864
                     /locus_tag="KNP54_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBF0894080.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            1905..2270
                     /locus_tag="KNP54_003217"
     CDS             1905..2270
                     /locus_tag="KNP54_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBF0894081.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            2371..3144
                     /gene="srlD"
                     /locus_tag="KNP54_003218"
     CDS             2371..3144
                     /gene="srlD"
                     /locus_tag="KNP54_003218"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBF0894082.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            3493..5637
                     /locus_tag="KNP54_003219"
     CDS             3493..5637
                     /locus_tag="KNP54_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBF0894083.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKGNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            5725..6060
                     /gene="spoIIAA"
                     /locus_tag="KNP54_003220"
     CDS             5725..6060
                     /gene="spoIIAA"
                     /locus_tag="KNP54_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBF0894084.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            6074..6502
                     /locus_tag="KNP54_003221"
     CDS             6074..6502
                     /locus_tag="KNP54_003221"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBF0894085.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            6525..7289
                     /gene="sigF"
                     /locus_tag="KNP54_003222"
     CDS             6525..7289
                     /gene="sigF"
                     /locus_tag="KNP54_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBF0894086.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAIKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            7569..8006
                     /gene="spoVAC"
                     /locus_tag="KNP54_003223"
     CDS             7569..8006
                     /gene="spoVAC"
                     /locus_tag="KNP54_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBF0894087.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            8173..9186
                     /gene="spoVAD"
                     /locus_tag="KNP54_003224"
     CDS             8173..9186
                     /gene="spoVAD"
                     /locus_tag="KNP54_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBF0894088.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            9200..9562
                     /gene="spoVAE"
                     /locus_tag="KNP54_003225"
     CDS             9200..9562
                     /gene="spoVAE"
                     /locus_tag="KNP54_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBF0894089.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            9745..10761
                     /locus_tag="KNP54_003226"
     CDS             9745..10761
                     /locus_tag="KNP54_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBF0894090.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            11136..11978
                     /locus_tag="KNP54_003227"
     CDS             11136..11978
                     /locus_tag="KNP54_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBF0894091.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            11993..12457
                     /locus_tag="KNP54_003228"
     CDS             11993..12457
                     /locus_tag="KNP54_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894092.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            12444..13616
                     /locus_tag="KNP54_003229"
     CDS             12444..13616
                     /locus_tag="KNP54_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBF0894093.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            13660..14595
                     /locus_tag="KNP54_003230"
     CDS             13660..14595
                     /locus_tag="KNP54_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBF0894094.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(14869..17562)
                     /locus_tag="KNP54_003231"
     CDS             complement(14869..17562)
                     /locus_tag="KNP54_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBF0894095.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDGGGNNGGGSTTPPDGGGTPAT"
     gene            17776..18474
                     /gene="yunB"
                     /locus_tag="KNP54_003232"
     CDS             17776..18474
                     /gene="yunB"
                     /locus_tag="KNP54_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBF0894096.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
BASE COUNT         6927 a         2196 c         3370 g         6003 t
ORIGIN      
        1 aatgatgatg gtgtgattgt cgagactaga aaaatgcaag gtgttacagt attggcaaga
       61 gtaaagtcat ttgaaggttt ggtaggaaag aacttagagt atatagaaaa atcagattta
      121 actgtttaca ataaactact taaaaaagca atactagatg cagtcaaaca gtacataaca
      181 tttgagaaaa ataaatgtga agatacaaat aatctgagta ctgatgaaga gtgtaggatg
      241 gaagtagttt aaaaaaatat atttataagg aggagttaat atgacgcaat tttttcaagt
      301 attagcaagt ggtgcagata gttttatgaa tttatttagg gcaggtgggc aacaatttgt
      361 aggttttgta acagatatag taccactttt agtagcatta ttagttacaa tgaatgcaat
      421 tatcaacttt attggtacag atagagtcga gagacttgca aaaaaatgtt ctgcaaatat
      481 atttactaga tatttgatat taccagtcct tggtacattt gtatttgcaa acccaatgac
      541 actatcatta ggaagattct tgccagaaaa gtttaaacct agttactttg cagcagcaag
      601 cttttcatgc catacaatga atggattatt cccacatatc aatccaggtg aactatttat
      661 atatctagga attgcaaatg gtataacaac tttgggattc tcaacagcag atttagcagt
      721 tagatatttg ttagtgggta tagttgcaaa ctttattaaa ggtgtagtta ctgactatac
      781 aacaaaattt gtagagaaac aacaaggaat agcattaaat tcagatataa agattggata
      841 attactttaa ggtataaata aatttttcaa ataaaaagat agtgtataga ggaggataaa
      901 ttatatggca tttaacaaag ttaaaatagt aaaaggttct ggaggatggg gtggaccatt
      961 gataatagaa ccaacagaaa agaagaataa ggtagtatat gtgactgggg gagcaaagcc
     1021 agaaactgca gtaaaaatag ctgaacttac aggatgtgag ttaatagatg gattttcaca
     1081 gggtgttaaa gatgatgaaa tcgcatgtgt aataataaat tgtggtggaa cattgagatg
     1141 tggtatatat cctcaaaaga aaataccgac tataaatata atgaaaacag gaaaaagtgg
     1201 accattagca atgtttataa aagaagatat atatgtttca ggggtaaaac caacaaatgt
     1261 agagcagtta taattgaggt agtaggaggg aagaaatatg gcttatgata ctaaaaagaa
     1321 gataagtgag cagagtcaag gaattgttgc aaaaataggt atagcactag gaaatgtgac
     1381 aagtactctt tttcaagctg gtagggatac tatagataca ttaatacata ctatactgcc
     1441 ttttatggct ttcgttgcag tcctaatagg tataataaat caatcaggta taggaaattg
     1501 ggtagccaat ttacttactc cattaatcgg aaatgttgga ggtttagttg tcttatcaat
     1561 aatatgttca tttccgttgt tgtctccgtt tcttggacca ggagctgtta tagctcagat
     1621 agtgggagta ttggttggta cagaaatagg aaaaggaaat attccaccaa gtttagcatt
     1681 accagcattg tttgcaataa actcacaagc agcttgtgac tttataccag taggtcttgg
     1741 tcttgcagaa gctgaacctg atacagttca agtaggagtt ccgtcagttt tatattctag
     1801 atttttaaca ggtgcaccaa ctgttctatt agcatggtta gcaagctttg ggttatataa
     1861 atagaagaat actttataaa taattagaga gaggttcagt tgatatggaa ttaatataca
     1921 gtactcaaat aaataaaata ggagataatg caaatgaatt tttacaacat aatatgtttg
     1981 taactttcaa agataatgct cctcaagagt tagaaaatta ctgttatata cattctgaaa
     2041 ataatttagt aaaagaaata cttacggatg atgtgctatc aataaataat gttgattaca
     2101 aaattacttc tgttggtgag ttagtaaacc aaaatctttc agaattaggt catataacat
     2161 ttaagtttac aggtgaaaaa gatggagcaa ttggaggaac cttatatctt gaagaaaaag
     2221 aaatagcacc tattggcgta ggtactatac taaaaataat tagaaaataa aatttaaaac
     2281 gaatctaatc atattataag taaattatag ataaaagtca atttaactaa tcaagttaac
     2341 ttttaatgtg ataaaaaagg ggaaatgaaa atgagaaaag tggctttagt cgttggagga
     2401 ggaagaagtt taggtgaata tttatctaaa catttagcta aagtaggtta tgatgttgct
     2461 attgcagatt taaatgaaga caacgcaaaa aaagtagctg aagaaataaa aactgaattt
     2521 ggttgtaaat ctgtaggata tagttgtaat gccatagatg aaagacaggt tataagtact
     2581 gtcaaagcta ttgaaaatga ttttgataga atagatttat tagtgtacaa tgcaggagtg
     2641 gctgtaagta aaaaaataac tgattttgga tacaaagatt ttaaatttat tgtagacgta
     2701 aatttaaatg ggtactttct atttgcaaga gaagtatcta aagtcatgat agcaaaaggt
     2761 attgagggta gaataataca gataaattca aaatcaggta gagtgggaag caagcataat
     2821 tcaggatatt cagcaggtaa atttgctgga gtaggactta ctcaaagttt agcgctagat
     2881 ttggcagaac ataagataac tgtaaatgca ctgatgctcg gtaatttact tgattctgat
     2941 atgtttgaaa gtttaattcc tcaatatgca gtaaaattgg gaatacctga atcagaagtc
     3001 aagcaagttt atatagataa agtaccttta aaaagagggt gtagatttat agatgttgca
     3061 aatatgctta cattttatgc ttcaaaggaa gctgaatact gcactggtca atctataaat
     3121 attactggtg gacaagttat gtaaggtttt tatggagtgt ctcaagatga actctttagt
     3181 tcatgaggca cttttttgta taaaattaaa tatattttca gcatttaaac aatgaaaaag
     3241 aggtttatct ttattttgag atagcctcat ttttgtaatt aaaaaacata gtgtttaagt
     3301 aaacatataa gattgttagt tttttaaaag agaatttttt aataatatta tatttatgaa
     3361 gtatttttaa acttattttg ataaaatata gctatgtttt atatactgta gttttgaaca
     3421 tagaaagttt aataaattat agtatatatg ttaattttta ataaggtaag aaagtagaaa
     3481 gaaggatatt ttatggatat aataaaaaaa ttaagtcatg ggtgtacatt agattgtcat
     3541 gactgttgta aattcaatgt ttatactaaa ggaaataatg tagtaaaaat tgaaggagat
     3601 aaaaatcatc cttatacaaa aggttttata tgcaaaaaag ggatggccca tttagataga
     3661 ttaaatcata aagatagaat aaagactcct atgcttaaag ttgatggagt atggaaagag
     3721 atttcttttg ataaagctat agaaataatg gcagaaaagc ttacatacta taaagaaaag
     3781 tatacatcaa agtctgtcat gcattatgac caatatggaa gtgggtctgt gctaaaatac
     3841 ataggagata tattttttaa tttttatgga ggtgttagca gacataaagg tggtccctgt
     3901 tggagtgcag ggatgcatgc tcaaaaatat gattttggag tagctaagag tcatgctata
     3961 gaagatatgt taaatagtaa aagtatattt gtgtggggaa aaaatccagc atatactaca
     4021 attcatacta tgcaaataat taaaaaagct aaagaaaaag ggataaagat agtagtgatt
     4081 gaccccatat atacaaaaac agctcaaata gcagataagt atgtacaagt aaatcctgga
     4141 acagatggag ctttagctat agctatggca aaaattatag tagaagataa attatatgat
     4201 gaagaatata taaactcgta tgttattggt tttgaagaat ataaaaaata tttatcttca
     4261 ttggaattaa gttttttaat tgatgaatgt ggtgttaaag agaatgatat aagagagtta
     4321 gtggatttat atactaacaa atattcaagt ataaatgttg gatatgggct tcaaaaatat
     4381 aaaaatggtg gaaacacaat aagagcaata gatgctttag gtgctataac tggtcaaata
     4441 ggatttagtg gtggaggggt aaactatgct aataaagttt atccgagtgt tataaattct
     4501 gacccttaca atagccaatc atatggtgaa gatagggagt tttatgtaag taatatcagt
     4561 aaatttatag aagaatcttt aaaaaataca tcaaataaag taaattatgc atcagatgaa
     4621 cttgatatga catcaaataa agtaaattat gtatcagatg aacttgatat aacatcaaat
     4681 aaaacagatt atatatcaaa tgaattgtat aatttatcta ataagtcaat caaaggtaat
     4741 attcctataa agatggctgt aataactaaa agtaatatgc tgaatcaact gccagattta
     4801 gtagaattgg agagggtgtt ttcaaaaatt gaatttaaag tatgttttga tatgtttata
     4861 actgatacag ctactttatg tgacatgttt ataccgtgta caaatacact agagagtgaa
     4921 gatataattt atagctcaat gaccaatcca tatataacct ataatgaaag agctgtaaag
     4981 ccagcacata aattgatgga tgaatattac ttctttatgg agctagctaa aaagatggga
     5041 ttaaatgatt atccttttgt agaaaagaga acttatttag aaaaagtgat tgaaccactt
     5101 aagcgttttg acaaaaatct ggatatagaa aaacttaaaa acaattactt tactatacat
     5161 aaccctgttg cttgggaaga taagaagttt gagactccat ctggaaaata cgagctttat
     5221 tcagaaagta taaaaaactt gggaataagt ccaacacctg tatatataag caataaatat
     5281 aaagaaatag aagataaaaa tatttctttt agattattaa ctaatcatca tgcagatact
     5341 ttatttagtc agcattttat ggacaaaaaa tctatagctc aagcatatat aaatcggaga
     5401 atggctaaaa aagtaggtat tgaggacaaa gatattgtga tattgaggtc aaaaaaagca
     5461 aaaataaatg tacaaataaa tatagatgat ggagtaggta attatatagt aaaaatgtat
     5521 gttggttggt ggaagaaaca tggaaatcct aatagtttaa cagacactgg tatatcagat
     5581 tttgggggtc aggtaacata taatgaaagt atggtagaaa taatacgaca aaactagtta
     5641 aatttcattg aaggaataaa aatataatta tagaattgat taaaagttac tatttttaca
     5701 aaactattga aggagggatt tttgatggta aattattcct tagaacataa gaatctatac
     5761 atagaattta tgtgctcaga actagaccac catgtagcca atgaaataag ggaagaaata
     5821 gataacttat taagtgtaaa tcaagtaaaa aatgttgtat ttaattttga aaatattaat
     5881 tttatggatt cttcaggtat aggcgtcatc ataggtagat ataaaaagat ttctaatgaa
     5941 gggggacgag tttcagtaat taatataagt tcacgagtta agaagatttt tgatttatct
     6001 gggttaaata aaattattgg catttatgat acgtatgaag aagctctaag ttctttgtag
     6061 ggaggagtat gtgatgaata atattatgga agttaaattt tcggcaatat ctgaaaatga
     6121 aagtttagca agagttatag tagcatcctt tgcagctaag ttagacccaa cagtagatga
     6181 gttagtagat ataaaaactg ctgtctctga ggctgttacg aatgctataa tacatggata
     6241 tgaagaagac agttctaagt ttgttttctt aagatgtgag atagaaggaa atactataaa
     6301 gattatagtt gaagatgaag ggtatggaat agaaaatgtg gagaaggcaa tggaaccact
     6361 ttatacatca aaaccagaac ttgatagatc aggaatggga ttcacagtaa tgaaaagctt
     6421 tatggacgat gtagaggtaa gttctgtaaa agataatggg actagaattg aaatgactaa
     6481 aaaaataaat gtgcctaaat aaagtccaaa agtgaggttt tattatggaa gtaactgttg
     6541 ccagagaaga aaaaaaacct cttcttagtc atgaagagac tctagaactt attgaaaaag
     6601 ttcaaaatgg agatgaagag gcaaaagaaa tattaatatc aagcaattta ggtctagtta
     6661 ggagcgttgt atctagattt ttaaatatag gatatgatag agaagattta tttcagttag
     6721 gttctatagg cttaataaaa tcaatatata aatttgaccc aaaatttaat gtaaaattct
     6781 ctacttatgc agtaccaatg attttaggtg aaataaagag atacttaaga gatgatggta
     6841 tgataaaagt atcaaggtcg ttaaagcaaa tagctataaa ggcaaagatg gaaagtgaag
     6901 ctttaactaa aaaattaggt agagagccga gtatagaaga attagctaaa gcaatagatg
     6961 tagaaaaaga agatttagta atggctatgg aagctaattt caatgttgag tatttgcaag
     7021 gagttattca tgaagaggaa ggttctccaa tatgccttat tgataaaata agcatgaaag
     7081 gagaaagtga agaagaaaaa gtagtggata acatattgtt aaaagacata cttggaagac
     7141 tggataagag agagcgtcaa ataatagttc tcagatactt tgaagacatg actcaaagtg
     7201 aaataggaga gatgctcaat atatcacaag ttcaagtatc taggatagag aagaaagtat
     7261 tgtctaagtt aaaagaatat atatcgtgat aatacttatg atatgtagaa taataaaata
     7321 taataaatat attactaaaa taaaatgtaa taacttttta tgttaagttt ttaaattatt
     7381 aaaagatatt aaaataataa aaagcattaa aaaagtaaaa atataaaaac aaggtgtctt
     7441 tatggaaaaa tagatttttt ctttattagg catctttttt attttttgac caaactttag
     7501 atagtcaaaa taaataatag gtttattttt ttaaaattaa caaataatac tttagagagg
     7561 tgtttagtat ggataaaaat tataaaaaat atgtagacca aataagccca aaacctacat
     7621 atttaaaaaa ctatacactt gcatttattg taggtggaat tatttgtatg atagggcaag
     7681 caataaatga tttgtatatg aaagttggag gtcttgataa actaggtgct agttctgcaa
     7741 catcaataac attaatattt ataggggcat ttttaactgg attaggagtt tacgacctaa
     7801 taggaaaaag agctggagct ggttctataa ttccaataac aggttttgct aactcaatag
     7861 tatctccagc aatggagtat aaaagagaag gctatgtatt aggtgtaggt gcaaacttat
     7921 ttaaaattgc aggaccagtt ttagtttatg ggataggttc ttctatttta tgtggaatta
     7981 tttattatat ttttaagatg ttttagatga tttttattta atttaaattt tattaattat
     8041 gaagaaggta taaaatctga aaatagctac taaagtaact aattgaaaaa taattctgca
     8101 gatttaatta atatttttaa ttaatattaa aaatttgaat agtaaaatgc aaaattaaaa
     8161 aggtgtgaaa atatgaaaaa taaaagaatt ggaaaaagaa cagtcaagtt agaaaataaa
     8221 ccaaccataa tatcaactgg aactatagta ggtcctaagg aaggtgaagg accactaaag
     8281 gactattttg atatgattat gactgacgat ttatatggtg aaaagacttg ggaattagct
     8341 gaaagtaaaa tggtagagac tgcatctcaa caagctatcc aaaaggcagg taaaaaattg
     8401 tcagatgtaa attatatgct aggtggcgat ttaataaatc aaatagttcc agcatccttt
     8461 gcagcaagag aactggctat tccattttta ggtatatatg gagcttgttc tacaatggca
     8521 gaaggtcttt gtataggttc tatgcttata gatggtggtt ttgctgattt agtactgtca
     8581 ggtacatcaa gtcactattg tacagcagaa agacaattta gattcccact tgaacttgga
     8641 aatcaaaaac caatgacagc ccagtggaca gttacaggag caggaagtgt attattagct
     8701 cctaatggag acggtccaaa agtaaagtat gttactgttg gtaaagtaat agatgagggt
     8761 attgatgatg gtaataatat gggaccagct atggctccag cagcaataga tactatctac
     8821 tcttactttg aagatactaa tgatgaccca aatagctttg atataattgc tactggagat
     8881 ttaggtactc ttggaaaaca gatagcagaa gactttctaa aagaaaaagg tgtagatata
     8941 tcaaaagttt atactgactg tggtatagag atgtttaacc ttaaagaaca agatgtccac
     9001 tgtggtggaa gtggatgtgg gtgttcagct acagtgtttg caggatatat atatgataag
     9061 ttgagaaaaa aagaatttaa caaagtaatg cttgtatcaa caggagcact actttcaccg
     9121 acaagtacac tacaaaagca gacaatacca tgtgttgcac atgcagtagt aatagtaaat
     9181 gagtaggaag tgatataata tgttaatgga ctatgtaaga gtatttattg taggtggaat
     9241 tatatgttta atagcccaag taatgatgga ttatttcaaa atgcaaactc catatgttat
     9301 ggtaacgtat gtaacaactg gtgtagtttt aacttttcta ggactttatg agccattagt
     9361 taagtttgca gcagcaggtg caacagttcc tataatagga tttggatatt cacttgctac
     9421 aggagtaata aaatcaattc aaagtgatgg ttttttaggt atttttttag gaggtacaac
     9481 tgctacagct ggtggaatag cagcagctat attctttgga tatattatgt cagtagtatt
     9541 tactccaaaa gcaaaaccat aaatctttat taaaagaata ataagttttt gaaataataa
     9601 ctttttataa agcaggtgga tatcttttag attccacctg ttttttatat aaagaagcgt
     9661 ttacataatt gaagttgaca attatttaca acatagtgta gtattatatt atcaaaataa
     9721 aatgaagtga agtaggggat aaagatggta actattaaag atattgcaag gaatctaggt
     9781 atcagttatt caactgtttc taggtgctta aacaataatc ctaatgtatc tgaaaaaaca
     9841 aaaaagaaag tggtagaaga ggcaaataga ctagggttcc attttaatgt aaatgcaaga
     9901 aatttagcaa aaaaagaaac taacaggata ggggtaatct tttcaaataa ttttaatcat
     9961 caagatacta gaaagttttt tagtgatata atggatagtt ctataaattc tattgagact
    10021 aataaatacg attttataat acagcctaat aataacatta gtggtgatag taatgtatat
    10081 aaaatggtaa atggacaaat ggttgacgga ttagtaattg tgtctcaatc aataaaaaaa
    10141 gaagagtatg attttttaaa agacaataat tttccacatg tatttatata ttttaaacca
    10201 tcttttatag gagaagtaga taatttcttt tgggacgata acgtgtatgg aggttatata
    10261 gctaccaagc atttaattga ccatggtcat aaagatataa taacagtaac ttcagatgat
    10321 aagagttcaa aaatgcatga agatagaacc aagggatatt tgaatgctat ggaagaagca
    10381 aatttaaaga cagaagtcat taaatctaaa atggattttg aatctcaagt tgaattttta
    10441 gaaaaataca ttgataaaat aaaaaaagct tcagctatat ttgtacaaca agatgtacca
    10501 gcgatttcta taatacaaga gttaaaaact acttatggta taaatgtacc agaagatatt
    10561 tccataatag ggtataataa tattgaatta atatcatatt ttaggtcgca tttatcaaca
    10621 atagatgacc caagagagca agttataaaa aatggagtag atagtttagt aaatataata
    10681 aataaaaaga gtacagaaca cattccaaga aaattatatc caaggttaat aatacgaaat
    10741 agcgttaaaa gaataaagta gtaagctttt aagtatcaaa cgtttattaa aaatattata
    10801 gattatgtga agttttttaa caaataatat aaataaaaat taaaaggagt aggtgtatat
    10861 aagtacattg tactccttta tttattgaga tagtttttat aatatgaatg aataatttta
    10921 ttcaattatt tgaaaatccg ttattttaac aatataaatt aataaattat ttgtatttta
    10981 tatcatgaat ctataatatt tttttgattc ataactaaaa gtatataaaa atgatgaata
    11041 aatatatatt atacattatc aatgataggt tatataataa aatcactaac aattatatta
    11101 taagaaaatt ataaaaatta caaggaggta tagaaatgaa agaaaaagca gggattagaa
    11161 atgccataat agcagccttt ataatcacaa tattggcaga attaattgga cctatttcat
    11221 ttaaagttat gggaattaat gtaactttac ttagtatact atgggctata ttcataggaa
    11281 tggctgtttc tcctcattta ttagggagag ttataccagc cttaaaaaag tttatagggg
    11341 ataatgaaat aaatgtatct ccatatttat tatctttgac actatatcca ttagggataa
    11401 tgtttggaat taatgcaggg cctaaagttg gtatattact tcaagcagga ccagcacttt
    11461 tattacaaga atttggtcat atgggtacaa tgttgatagc attacctgtt ggagtagcat
    11521 taggtcttgg aagaagtgca ttaggtggta ctttttcatt atgtcgtgac acagcactag
    11581 gaattattgg agataagtat ggattaaact caccagaagg tataggaaca ctaggaactt
    11641 acataagtgg tagtatattt ggaacattat tattttcatt tttagcacca gtgggtgtac
    11701 ttttaggatt tcatccatat gctttagcaa tggcatcagg aatgggtagt ggttcaatga
    11761 tgggagctgc aacagcatca ttaatgaata cagttccaca aatgtcagag cagattttag
    11821 catattcagc tactagtgga ttgattacag ctgttactgg aatatatata gaattattct
    11881 tatctttacc agtagccaac tactattata gcaaagtagc tccagttatt gaaagattta
    11941 gaggaagaaa aacaagaaga acaagtaata aattgtaaag gaggatatat atatggaaaa
    12001 aacttttaag actattatgg agcagataaa aatagtattg tttatatata ttattatttg
    12061 ctttggacaa atgatagcac ttaagactca ggctcaagat ttgttgattg gaagtgtatc
    12121 tggatttttg ttggtgataa ttgctattat aataaagaat tttgttaaaa aacctaattt
    12181 accaggtttt gcatgggcta cattagttgc atttgtttta tcgcttccaa tatctccagt
    12241 gggggatatc atagcaacaa atgtagggaa aatcaatttt atgtctacag taacaccatt
    12301 attagctttt gcaggaatct ctgtaggtaa tcaattagat atattaaaga ctttgagttg
    12361 gaagttagta gttatatcat ttatagttat gacatctact tactttggtt ctgcttttat
    12421 atctcaaaca gttttaagat taaatggaat gctttaagga ggtagtaaat atgaatgaat
    12481 taaaagcaaa aattaaagag gaaataaagt tattatctga agagaaaaag acatcatttg
    12541 aaaaagtttc tgactattta ttttcaaatc cagaattagc atttgaggag tataagtcac
    12601 aaaaagcatt atgtgatttg ttagaagaaa atgaatttaa tgtaactaaa ggtgtaggag
    12661 gattagaaac atcttttgaa gctgtgtatt caaatggaac taatgggaaa acagttgctt
    12721 ttttagctga atatgatgca cttccaggaa tgggacatgc atgtgggcac aatatcatag
    12781 ggacaagttc tgttggtgca ggtatcatat taaaagaaat catgaaaaaa cataatatag
    12841 aagggactgt aaaggttttt ggaacacctg cagaagaaag agtaggtgga aaaataacta
    12901 tgattaaaga aggtgtattt aataatgtag atgctgcatt aattttacat ccaagtgatg
    12961 cttcaatgcc tgatgatata tcatttgctc aagttaattt aaaatttgat tttactggta
    13021 aggcatcaca tgctgctgct tttccttggg aagggaaaag tgccttaagt ggagtaatag
    13081 cactatttaa cagtgtaaat agcatgagat tacatcttaa agattatgca agagtacatg
    13141 gaattataac tgatggaggt agcatacata atataattcc tgaaaaatct acagctatat
    13201 ttaatgtaag agccttaagt atagaatatt taaatgagat ttgtgaaatg cttaaaaatt
    13261 gtgctaaagg agctgcaatt tctactggaa ctaatgtaga aatagttcaa ttagatgaaa
    13321 tatacaaaga gattaagaat gattctgaat tagtgaatat agttagacaa aattttgaag
    13381 ttttgggtga agactatgtt gaaagagatt taagtcaagg tataggttca actgatacag
    13441 gaaatttaac tcatgagata cctgcaatac aagcatatat aaaattaaaa gaaaatactg
    13501 caactcatac agatgaattt gctgttgcag ctggtggtga agaaggcaga gtagcactta
    13561 taaaagcaat taaggtgtta gcaatgtgtg gagtagatat tttgtatagt aaataatata
    13621 taattttaaa atatattaag aaaggaaatc ggattagaca tgatattaaa acaagtaata
    13681 gaggtttatg acattttaga taaagcaaat gctaatgggg aagaagtaaa aacttactta
    13741 caaggttatg gtgaagtaga tgtaactgta aaagaattgt cttcaagtaa aggttcaaca
    13801 gatttagtaa agcttacaat tcctggaaaa aatggaaaat taaaaggtgg agatgctcct
    13861 actcttggta ttttaggtag actaggaggg attggagcaa gaccagaagt tataggtttt
    13921 gtctcagatg gtgatggagc attggtagca attgcagtgg ctgctaaact tttggatatg
    13981 caacgaaaag gggatatatt agatggtgat gttgtaattt caactcatat ttgcccagat
    14041 gctccaacta aagaacacta tcctactcct tttatggatt ctccaattga tatgatgact
    14101 atgaatgaaa atgaagttga tagtagttgt gatgcaatac tttctataga tactactaaa
    14161 ggaaatagag taatcaatac tagaggattt gcaatatcgc caactgttaa agaaggctac
    14221 atattaaaaa ctagtgataa ccttttagat attatgcaga ctgtaacagg gaaatctcca
    14281 tttgtattcc ctttgtctat tcaagatata acaccatatg gaaataatct gtatcactta
    14341 aatagtattt tacaaccagc agtagctaca gatgcaccaa tagtaggagt agcaattaca
    14401 acagagatgc ctgttgctgg atgtgctaca ggtgcaacta attttagtga tttagattca
    14461 gctgggagat ttgcaattga agttgccaag ctatttggta gaaataagtg tgatttctat
    14521 gataaagaag agtgggaaat gcttattaag agatatggca aattaaatag atttcaaaca
    14581 tttggtatac agtaattaga aaaatattaa gtttatataa tttgtgatat aactatttaa
    14641 gaatatataa acaattagga ataaaagtaa gaataaagca cttagttaaa aactttaaaa
    14701 ataaaatatt tatttgttta tataaaaagg aggattctgg ttattgggat tctctttttt
    14761 atgaatacaa ataatatatt gtaattataa aaaaaggagc gtttcaaagt gattttttta
    14821 atcaccttga gacaactcct tatattttta tttaaattct attttttatt aagttgctgg
    14881 agttccacca ccatcaggag gagtagtaga gccaccacca ttatttccac caccatcagg
    14941 aggagtagta gagccaccac cattgtttcc gccattatca ggaggagtag tagagccacc
    15001 accattattt ccgccattat caggaggagt agtagagcca ccaccattgt ttccgccatt
    15061 atcaggaggt gtagaaccgc caccattatc acctgtgtta ttattgttat tattattttc
    15121 ttctggttgg ttattgtctg gtttttttgt atcttcagat gatggttgag aacttacttt
    15181 agtaggagca gtaccttcaa taaatgctgc tttagagcca gaagattgct ttcctccatc
    15241 ctctaaatta atttttgtaa aatatacatt tttaggaact tcaaattcag taaccgttaa
    15301 attagcatgt attttttcca taattttttc ccatagtttt gcagtactag tacttccatg
    15361 tggtacttct ctacgtttta tagtgttacc agaatcatct tttctaccag catcatctcc
    15421 aatataagtt gcaccaacat aataaggagt gtaaccgaca aaccaagcat catatgcact
    15481 atttgtagta cctgttttac ctgctacagg cattcccttt ggaagtgtag caacaccacc
    15541 agtaccttca gtaattacgc tttctaacat atctgtaaca acataagcta cttcagggtc
    15601 tacaacttta tgttcttcag gagcattttt aactaataat tgaccatcaa aggtagttat
    15661 agtagtaaaa atagaaggtt ctacataaat accgtgattt gccaatgtac cataagcagc
    15721 agccatttga agtggagtaa taccattcgc cataccacct agtgtcaatg atgggaattt
    15781 tctatcactt gcttcagatg aacctgagtg attattcttt aaagttgtta taccaaagtt
    15841 ctttaagtaa tccatcatta tatctacaca ttcatcataa gagtctccaa gcatttcagc
    15901 agttttgaca gctatcgtgt ttgaagattt agcaagtgct ttacgtaaac tcatagaacc
    15961 atgaccagca gtagtagttc ttggattcca tttattattt tcttcaaact tatatcctcc
    16021 tcgagaatca cttagagcag ttgcttgtgt tatttttaga gtatcaatag ctggcgtata
    16081 tattgctaaa ggttttatag aagaacctgg ctgatgaggg ttagtagcac gatttaaagt
    16141 ttttctacca cttatatttc ttcctccagc tagtgctctt atttcaccat ttttataatc
    16201 taagattacc attgcagctt gcggttggct aactccatca ggaccgacca tatgtcctgg
    16261 gaaattgcta tttctatcaa attcttcttc taaagcatct tgcattttag ggtctatagt
    16321 tgtgtttaca attagaccac cattgtagaa taagttttga gcttcatcat ttgtatgtcc
    16381 ttgttccatt aaagcattta taacttcact ttcgataagg tcttctacag atgaagaaac
    16441 tttatctgat gattgaggca attttatttc tattttagct ttgattgctt catcatattc
    16501 actttgtttt atatatttca attctaacat tttctttaaa acaatttctt gtcttttttt
    16561 agcttcagga ttacttacag cctttctaac aactaatgta cctgctttta attgtctata
    16621 agtatcatta gatataagct cccaagattt tattttttca atcatatcaa agtccacttg
    16681 agtagggtca tctaaatcat catcagttgt gttaacaaaa aataataatt tattctctaa
    16741 atcctcctta gtttcatttc cctctaactt agaagtttta taggctgaaa atcttgatgg
    16801 atttttagtt gaaccagcaa gaagtgctga ctctgctaga gtaaggtcag ctgcagactt
    16861 atcaaaataa ccacgtgcac cagcctcagc acctgctaga cctctaccaa cgaagaagtt
    16921 atttaaataa gtttctagta ttttatcttt acttactgtt ttactcatct catgtgcata
    16981 gtaaatatcc tttattttac gaggtatagt ttgctgttca gttgttaaca gcattttgga
    17041 tacctgcata ggaatagtac taccaccttg cttagtacct gtaagggtct ttaatactga
    17101 cctaaataaa cctttaatat cgacaccctt atgctcataa aaacgctcat cttctattgc
    17161 aattacagca tgttgaagat aaggggaaat cttatctaat ggaacgggtg tctttttatt
    17221 tacacttgga gctgtagata atgtttttcc attagcgtat ttaatagtag ttgtttggtt
    17281 cgtctgttta tctaaaacag cttctgtaac tggagttaca tctcttagtg acgcaaatac
    17341 tagaccagca gtacctgctg taccaacaac tagtaaaact aaaaatacta tcccaaatac
    17401 tcttagtttt ttaaatttat cgcttttttt agattttttc ttgttttttg ttgaacgagt
    17461 cttgttagct gaagttctat taattggttt atttgtatta ccagatgagc taactttttt
    17521 tctcctgatt ttatttccat ttttatcatt atcgttattc ataagatttt aacctcctta
    17581 cttaatgcaa tattataaca caaataggag tagttttgta attaatagaa aaaatgaatt
    17641 tgctataata ttctgtacat tgtatatgta taaacgtaat atattaaaaa gtctatattt
    17701 ttattttatt tatttttgac aaatattata aaaattatgc caaagctaca tataaataaa
    17761 taggagggga taattttgaa tagaatagta gatagaaaaa caaaaaatga atttagaaaa
    17821 atcatagcta tttttttagt aattcttttc ttgtctgtat ttataggcag ttttatatat
    17881 atagataaaa ctttaagacc gacaataaca gttttagcag agactaaagc tcttgaacta
    17941 gcaaataggt cgataaataa agctgttgct gagatggtag aaggaaaaat aaattatgaa
    18001 gatttaatgg atatacaact tgataataat ggtaaaataa ctatgataca agcaaacact
    18061 ataatgatga atgaaattgc atctgcaata gctttagaaa tacaagatga attaaaaaag
    18121 gataagacag caagttctta catacctata ggaacagcat taggaagtcc tatattagct
    18181 aaatacggtc ctaaacttga agtatctatt gaacctatag gaacagtatc agtaaacttt
    18241 aaaacggaat ttgagtcttc aggtataaat caaactagac atagaatata tttagaagct
    18301 caaacacaag ttaaagtagt aataccactt ataacttcaa caaaacaaat taaagctcaa
    18361 atacctattt gtgaaactat aatagtaggt gatgttccag aaagttatgt aaatattcca
    18421 gaaaaaaatc taggaaatgt tttacctaac actggaaaga ataccaacaa gtaatgtaaa
    18481 gttgtatatt tttaaa
//
LOCUS       DAEHWO010000085        18222 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEHWO010000085 DAEHWO010000000
VERSION     DAEHWO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18222
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.085"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(122..973)
                     /locus_tag="KNP54_003233"
     CDS             complement(122..973)
                     /locus_tag="KNP54_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBF0894097.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            complement(1022..2191)
                     /locus_tag="KNP54_003234"
     CDS             complement(1022..2191)
                     /locus_tag="KNP54_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBF0894098.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            2662..3579
                     /locus_tag="KNP54_003235"
     CDS             2662..3579
                     /locus_tag="KNP54_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBF0894099.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            complement(3708..4637)
                     /gene="pfkB"
                     /locus_tag="KNP54_003236"
     CDS             complement(3708..4637)
                     /gene="pfkB"
                     /locus_tag="KNP54_003236"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBF0894100.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            4906..5631
                     /locus_tag="KNP54_003237"
     CDS             4906..5631
                     /locus_tag="KNP54_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0894101.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            5714..6868
                     /gene="nagA"
                     /locus_tag="KNP54_003238"
     CDS             5714..6868
                     /gene="nagA"
                     /locus_tag="KNP54_003238"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBF0894102.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYVPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(7577..8047)
                     /locus_tag="KNP54_003239"
     CDS             complement(7577..8047)
                     /locus_tag="KNP54_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBF0894103.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIY"
     gene            complement(8651..9808)
                     /locus_tag="KNP54_003240"
     CDS             complement(8651..9808)
                     /locus_tag="KNP54_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBF0894104.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            9962..10531
                     /locus_tag="KNP54_003241"
     CDS             9962..10531
                     /locus_tag="KNP54_003241"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBF0894105.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            complement(10713..11129)
                     /locus_tag="KNP54_003242"
     CDS             complement(10713..11129)
                     /locus_tag="KNP54_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894106.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(11355..12449)
                     /locus_tag="KNP54_003243"
     CDS             complement(11355..12449)
                     /locus_tag="KNP54_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894107.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            complement(12872..13813)
                     /locus_tag="KNP54_003244"
     CDS             complement(12872..13813)
                     /locus_tag="KNP54_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBF0894108.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEVIIAKRM"
     gene            complement(13806..14633)
                     /locus_tag="KNP54_003245"
     CDS             complement(13806..14633)
                     /locus_tag="KNP54_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBF0894109.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            complement(14804..15187)
                     /locus_tag="KNP54_003246"
     CDS             complement(14804..15187)
                     /locus_tag="KNP54_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBF0894110.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            complement(15156..15443)
                     /locus_tag="KNP54_003247"
     CDS             complement(15156..15443)
                     /locus_tag="KNP54_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBF0894111.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            complement(15476..16633)
                     /gene="alr"
                     /locus_tag="KNP54_003248"
     CDS             complement(15476..16633)
                     /gene="alr"
                     /locus_tag="KNP54_003248"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBF0894112.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEKSVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            complement(16648..17238)
                     /locus_tag="KNP54_003249"
     CDS             complement(16648..17238)
                     /locus_tag="KNP54_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894113.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQDDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            complement(17259..17720)
                     /locus_tag="KNP54_003250"
     CDS             complement(17259..17720)
                     /locus_tag="KNP54_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBF0894114.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            complement(17735..18115)
                     /locus_tag="KNP54_003251"
     CDS             complement(17735..18115)
                     /locus_tag="KNP54_003251"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBF0894115.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
BASE COUNT         6105 a         3034 c         2090 g         6993 t
ORIGIN      
        1 aaaagctgat atttttcatc aattaaatga aaaaaataca ccatttacat ataattaata
       61 taaatttttc atataataaa tatcctaaac ttatctaaaa taaatttagg atattttatt
      121 tttatactct atttacagac ccacacactt taatcttttc tttcacaaaa tcctttactg
      181 attgaagccc tgctaatcca tactttttag ggtctataac ctcagaatct tcatctaaaa
      241 cttttttaac ccctttacta tatgcaattc ttaattcagt tgcatagtta acttttgcaa
      301 tacctctttt tatagcttct tttataatat catcatgtat tcctgaacct ccatgcaata
      361 ctaaaggtat tgaaactaca tttttaattt ctgataacct atctaaatct attttaggtt
      421 cacccttata caatccatgt gcagtaccta tagcaatagc caatgaagat attcctgttc
      481 tatcgacaaa ctcttttgcc tcttttggat ttgtataatc attactattc ccgccatcta
      541 aatcatcttc ttttccacca actttcccaa gttctgcttc cactggtata agagaaggac
      601 tacatgcttt tactactgat ttagatatag atatattatt ttcaaagctt tcatgagaac
      661 catctatcat tattgatgta tatccacttc ttaaagcttt cattgcaagg tcaaaacttg
      721 aaccatggtc cagatgcatt gctacaggta tatttactct ttctgcagca acctttgcat
      781 ttgctagata ataatcaaga cctgcatatt ttacagtaga tggagtagtt tgtaatatta
      841 ctggagaatt taactcctca gcagcttcta taacagcaat taccatttcc atattttcta
      901 cattaaatgc tcctactgca tacccttcat cttgtgcctt tttaagcatt gatgttgttg
      961 ttactaatgc cacattgata ccctcccaaa ttatttagtt ataatatttt aatcttatct
     1021 tttaatattc atatattgtt acacctttta ctactcgatt tactgttcct gtagctgatg
     1081 gagtatctgg cttatttcca acctttactg atacaaacaa tgctatagtt tgtgcaaaca
     1141 atatgtatgg cattgcaaga tacacatctg gtaatttatt atacttttct ttaaactcaa
     1201 actttgttcc tgagaagtta ttttcatttt ctactgacac tgcacaagtg aatttagcaa
     1261 ttttatccct ttttatctcc tctaaaacat ctaaatcata ttttcttgta tataaacagt
     1321 tagatacaaa ttcaaataca agtgtatttt catcaataaa tgattttggt ccgtgtctaa
     1381 accccatagg agaatcatac actgtagata tttttcctgc tgtaagttct aaaagtttta
     1441 gttgtgcttc ttgtgtcaaa ccacctaatc ctcctgaacc taaatataca actctatcaa
     1501 aatctttatt tattaactca tgtatttcat cttttctatc tataacattt cttcccattt
     1561 caattattgc atttatatat gacttttcta catcatcttc taaactatcg aatattaaca
     1621 tagcagataa catcatacac gaaaaacttc ctgtcatggc aaagccttca tcatttgatt
     1681 ttgatggcat taataacaag taattatttt cgtcgttttt agtcatctta gccagttctc
     1741 cttctggatt acaagttata gctaaatgat aaaaattatc tacaatctta ttccctaaat
     1801 ttaaagctgc taaactttca ggactatttc cacttcttgc aaatgaaatt aataatgttg
     1861 gtatatcttt ttttaagtaa tcatatgggt ttgaaactat atccgtagta ggtattgctt
     1921 caaatatgta ttttcttatg tcatttttat ttttaaggta aggaagtatt gaatttccta
     1981 tgtaagctga agttccagca cctgtaaata taactctaaa ctgcccatga ttattactta
     2041 ttgtatctat gaatctactt aatttttctt tgttagattt atatatttca taagtttcta
     2101 accataattc aggctgttgt tttatttcat tagttgttat tattgcacct aaatctttta
     2161 gtttttgttc ttctaattta aacattttca ttctcctttc atacttgtaa cgtttacatt
     2221 tggtaatgag gttataacca ctttaaacta taaaaaaata tactctttta taattttttg
     2281 cttagatttt ttagtactac ttaaactcac tataaaatat acactataga ttttaattaa
     2341 ttttatagtt tatctttaaa aatttaataa aatcatactc tatatacttt agtattttta
     2401 ttttacgata aaagcttgtt cagaccaaag tggtaattac cactaatcca aatataaatt
     2461 aatttgaatt ttttgtcaat acataaaata tttatatcaa tcaattttat ggatatccta
     2521 caaaattact ttatcaatat ttcttatttc gctaatttac ttatataagc tttaaattta
     2581 ttttttgata caaagtttac aaatttatgt gtctgaatta taatcaattc tgtaaatata
     2641 aaaaccttag gagaaagtat tatgaaaaat ataaaaatgg gaatgatagg tcttggctcc
     2701 atagctcaaa aggcatattt acctatatta actaagtctg agagatttga gtttgtagga
     2761 gcttttactc caaataaagt taaaagggaa aaagtctgta gtgattatag aatcatgcca
     2821 ttcgattcta ttgaatccct agctaaaaaa tgtgattgta tttttctaca tagctctaca
     2881 gaaacacact acgaaattat aaaaatatta ttaaatttag gtgttcatgt atatgtagac
     2941 aaacctcttg cttcaacagt aagtcaagga gaagaactta tcgagttaag tacgaaaaaa
     3001 aacttaaatt taatggttgg attcaaccgt agattctgtc ctatgtacaa agaaattaaa
     3061 aataatgcta cagaaattgt atctatcaat atatgtaaac atggattaaa ttccttaaga
     3121 aatgttagat tcgacagtac tcttatagat gactatatac atgttattga cactgcttta
     3181 tggttagcaa atgaagatgt tgaaattagt ggagaggatt tatttttaac agacaataag
     3241 aatcttatat ttgtaagtca taaacttaaa ggtaaaaatt tctctataaa cacctctatg
     3301 catagagatt ctggaacaaa gttagaacaa gttgaaattc tttcaaaggg taagattcaa
     3361 agagttaaga atcttaatgt actggaaata gaagaaggtg gaaacctaac tttaaagcaa
     3421 agtggtgcat gggtaaatat attaaaacaa aagggttttg aggatatatc aaatcatttt
     3481 attgattgta tagaaaataa tataaaacca gctattaatg gagaagagtg tatcaaagct
     3541 caaagattac tagagaaaat tataaattca gtaaaataga tatttattat aaaaataggt
     3601 taaaaatgaa tttttctaac ctatttttat ataagactat atcttttata ttaaaattaa
     3661 aatctattac aacaacatta aatttattat attcccatta aatgtattta acttaacttt
     3721 tttacttcaa ctaaatcttg atatttatca atttctccca aatctacaaa tccagtttcc
     3781 atatttaaag cattacttat accacaagca tttgcaaatt taagtaaatt ttctatttta
     3841 taacccctta aaatacctac actaaatcca gccactgtgc tatctccact acctacagta
     3901 tttatacact ttacaactgg tacttttaca tcatatacat tatcttcgtt taaatacacc
     3961 ataccatctt ttcctaaaga tatacataca ttctctgcac ccatttcaat aagttttttt
     4021 cctgacaaga taatttcctc tcttgattct atattcattc ctaataaatg tcttatttca
     4081 tctatatttg gttttattaa atatggtttt gattttaaag ctatttttaa tgcttctcct
     4141 gatgtatcta atataaactt tatattattt gctctacata tatttcctat cttttcataa
     4201 tagtctatcg gcatattctc acaataacta ccagaagcta ccagtatttt agtatttttt
     4261 agtacttcct ctatatcatt ttcaaatctc tctaaatcgc ttttttctac tattggtcct
     4321 ttttctaaaa attctgtact aactttattg tcctcaatta tgtttaagca atttctagtt
     4381 tcctgctcta tttttgtaaa tttattttgt atatctagtt ttctaagttc attttttata
     4441 aattctccat taaatccgcc tagaaatccc atagctaaag gattttcttt taaaatttta
     4501 cataccttag ctacgtttaa tcctttacct ccagcagttg cattcttact tactaccctt
     4561 tgcacctcac ctatgtttat attattcact ctatacattc tatctataga tgggttgaat
     4621 gttattactg taatcatact agattctcct cattattaat ttttactttt ctaaacaata
     4681 aattaatctg taaaataaaa aatacctcat ctataatata cccaaagtgg ttattaccaa
     4741 tttgaatata aattatttta cttgttttgt caatgtacca taattttata ataaattaat
     4801 aaccttactt attgaatttt gattaaactt tattcattga cataaataat tctatattct
     4861 ataatcaaat tgtggtaata accacttaga aaggactata tttttatgat aaaaagaaat
     4921 gataaaagac caatatatga ccagcttgtt gagatattaa gaactaagat tgaaaatgag
     4981 atggaaccaa acgatagaat gctttccgaa agaaaaattt gtgatgaata tggagtaagt
     5041 agaaccacag ttagactagc tatggctgag ttggaacata tggggtatat atacaaaaga
     5101 catggaaaag gaacttttgt tgctgcacta agtcaaaatt ctcaaaactt aatggaaagt
     5161 tatagtttta cagattatat gagaacacaa ggaaaaaagc caggtacaaa ggtattatca
     5221 tttgaggtag tagaaagtac aaagtatttc tctgaaaaat taggtataac tcctggtgaa
     5281 aaaatgataa aaataatgcg tttaagactt gctgatgacc ttcctatgat gcttgaaaga
     5341 acatatcttc ctatgaaaga atttatagga ttgacaaaag aaaaaatcga acaaaaacct
     5401 ttatatgaaa tatttagaga agattatggc gagattatta aagttgctga tgaagaattt
     5461 tcagctggaa taatctctga taaggaagct aagttattgg aagtaccagg agattcacct
     5521 tgtctgaaat tacttcgtac cacatataat gatgacaata tagttattga atttactttg
     5581 agtgttgcta gaagcgataa atttgtatat agagtaagac atgtaagata gtaagttaaa
     5641 taactttcaa gaaaatagaa tgatattata aacgtcaatg ccacaatgat agtataatta
     5701 taaggaggtt attttgaaaa gttttattta tgcagataaa ttttttatga aacatggaat
     5761 caaagaaaaa ggttacctta gtataattaa tggcaaattc ggtgaatttc aacaagaaag
     5821 acctaatgtt actgataatg ttatagattt ttcaggtaaa tatattgctc ctggcttagt
     5881 tgatactcac attcacggtc ttttaggtgc agatgtcatg gacaatacat ttgaagcaat
     5941 aaacacaatt tcaaaaggct tattaaaata tggagtaaca tctttcctac ctacaacttt
     6001 aactgattct gtagatacac taagtgattc tgtagaaaat ataagcaata gcttcaatcg
     6061 agttgagggt gcaaaaatac aaggtattta tttagaaggt ccatttttta cagaaaaata
     6121 taagggcgct caaaatgaaa aatattttaa agaccctgac atcaatatat taaaattatg
     6181 gcaaaaaaaa tcgaaaaatt taataagaaa aatagcaatt gctccagaac gtaaaggttc
     6241 aatagaatta acaagatatg caactaaaaa taatatatca gtttctcttg gtcatagttc
     6301 agctacattt gagcaagtta aacaagtcgt taattcaggt gctaaagtgt ttgtacatac
     6361 atataatggg atgagtcctt taaatcatag agaacctgga atggttgggg ctgctatggt
     6421 actaaaagat acttatgctg aattaatttg tgatggtcat catgtaagcc caatagctgt
     6481 taaaataatg atggatgcga agtctagtaa taacatagct ttaattacag attgtatgag
     6541 agctggtgct atggaggatg gaaaatatac tcttggtaag tttaatgtaa atgtaaaaaa
     6601 tagtgttgca agattaaata gtgggagttt agctggaagt gtattaacta tggacaaggc
     6661 tgtgagaaat atagttgatt ggaacatatc aactttagaa gatgcaataa aaatggctac
     6721 atatgtccct gctttaagtt gtaatattga taatgtctgt ggctctatat atcaaggtat
     6781 ggatgcagac tttatagtaa cagataatga ctttaatata cacgaaactt atataaatgg
     6841 tatctgtaag tacaaagtta ataaataggt tcaatataag gttatggagg ctgtctaaaa
     6901 agagtctgga aatatttaaa gttatttctc caaaatctga tttaacactt ttatttccat
     6961 atcgttaata aactattgcg atagaggtta ttttaaacaa atatatatta taagtatttt
     7021 tgtgataata ttttcgataa tatgtacatt taaagtaact tttctattat tatttgtaag
     7081 tttttatctt gagcaaacat ataaattttt aataaagcat gagataaacc ctatatttca
     7141 attactaatg atgagatttt gattgataac agatatattt tcaaatgtaa aaatactaaa
     7201 aatcatatca attttaaaga tattgtaggt gtaaataaac aagataatac tatagaaatt
     7261 tttacaaatg aaagcactta ttgtatatat ctaaaagttt taagcattga gagcgaagaa
     7321 tatctaatag atagactaaa atcattttgt tgattttata tattttatgt taaatataaa
     7381 gcagagtagt taaaactacc ctgcttttgt aattaaaatt taaaaataat aactcataat
     7441 acattgaatt tgagcttaac agtaactatt gtaataatag tatcaatctt ttgtgttgaa
     7501 tataatttat ttacactata gttaagcatg atttctaatg ttattttctc taatttacaa
     7561 ttatgattaa aattcattaa tatatatatt tataagttgt attgtttata ttgtttatta
     7621 cttttttaaa tccactagct gtaataataa atgtcttttc tggtatccct ggtgaaaaga
     7681 ttattttatc atggttaaat atatcttgat ctattacaag agagatattt ttctcatatc
     7741 caaaaggaga tacacatcca ggcaaacatt gtgttttttg tgttaattct tcttttgaac
     7801 atatagatac ttttccacct aaaacatttt ttatagtttt tggatctaat ttttttcctt
     7861 ctgtggttac aaatatatag taatttccag atctatcttt tataaataaa cttttacttt
     7921 ctactccagt atattgtaat ttttctctta tttctttagc tttttcaaat gataaaatag
     7981 gttcatggtc atattcttca aacgttatat gattttcttt taaaatattt ttgatattgt
     8041 tgtacatata ttttcctttc tatatttaaa ttaatttata tataatattc aattataaag
     8101 tgattttata atttcttcaa actatcataa aaaacattca catgttttag gaataaatta
     8161 tataaaatag gttataagat aatgaacatt tatattataa cctattttta tatcgataag
     8221 tatgaaattg tttaaccaag tcaaaatgat atataaattt atatttaaat gtgtttagag
     8281 tttaatttat tttcaatgtt taaaaaagtt attctatgca tctaatttaa ttagtaaact
     8341 gaggttctag ttagataaat tatattataa tgaatatata gtatgcagtt tacgatattt
     8401 taaaagtaaa tgatataata tttggaacaa ctgggttgca atgtgttttt aaaaaatatc
     8461 aaaataaggc tatgattttt aaaaccatag ccctgtctgt aaaaatttaa ttatcactta
     8521 aaaaataaat ttttatttaa agaatacaca taaatatttc cagactccct catgaactaa
     8581 aaagttcatt ttgagacatc tcttttataa tgttctttat tttatagtat aagtttataa
     8641 aaattaaatc ctatttatca atctgttctc taagccactt agttgctaca tctaactgtt
     8701 tattttcatc tttttcttca atagtaggct ttataccttt ttcattgata taatctccat
     8761 taggtgtaaa atattgagca gtagttaact tgtatcctgt tccatccttc aatcttacaa
     8821 ctgattgtac caacccttta ccaaaagttg tagtccctac agaaatacct tctttattat
     8881 caacgattgc agctgttaat atttcagcag cagaagcact ttctccatta gttaacacta
     8941 ctattggaag tcccaatttt tctttatcag atttcaagta ctcagtattt cccttattat
     9001 cttttgtata tactatagtt ccttcaccaa ttaactcatc agcaacttct ttacatatat
     9061 ctagcattcc accaggatta tttctaaggt ctattactaa tcccttgata ttttttgctt
     9121 ttaattcttt taaagcttta tcaaagtcag tatatgtact tgatataaat tgggtaattt
     9181 ctatatatcc taaatcatta tcaattactt tactttctat actcttctca attatctggt
     9241 ctgtttttac tttaaagttc aattgtttat cttctcttaa tatagtcagt tcaactgttt
     9301 tacctttttt acccttcatc atacgaacag cttcatctga atttttatat gagacagatt
     9361 ttccattgac ttttactaat ttatcccctg attttacacc tgctttctct gctggagaat
     9421 ctttcatggg aactactact aagccaccat cttttgatgc ccctatatac atacctacac
     9481 caacataaga accttcacta tcattaatta gattctccat ttcatcttta gtataataac
     9541 cagaatactt atcatttgtt cctagaaata gaccttttgc tgctccattt accaaatcag
     9601 tatctgatac ttttttataa aaatcttgtt ttataataga ttctagtcct aacaacttat
     9661 catatttttt atagtcttca tagagttctt tcgatattac aactttattc cccaatgtca
     9721 actgaaatgc tgatgtaacc atagctgtta taattactaa aatcacccct aaaaaaatag
     9781 ctttcttctt tgaaatcaca agatacatct ccttttacat aaactattat tattatatga
     9841 ctagctgtta tttttattac atttacccaa atatattgct ttattacaat aaattatact
     9901 aaaatttata ttaaatacaa ttgctgtaca cattataaca tattaaggga ggaattattt
     9961 tatgaaaaaa gaatttagaa aaaaagttat tgaatcaaga aaaaataaga gtgcaaactt
    10021 cgtacttagt aattcaaatt taatcactga aaaattactt caaatggaag atataagaaa
    10081 tgcaactaat ataatgcttt atctaaattt taacaatgaa gttcaaacag ataatttaat
    10141 caaaaaactt ttgtctctaa agaaaatagt atcaagtccc atcacaataa aagaaaatca
    10201 tacattaatc cctactcaaa taacagattt aaaagaggga ttgagaattg gagcatatgg
    10261 aataagagaa cctaacgaaa aatcacctac aattgatatt aaggccttag atgttgtaat
    10321 tgtaccagct gtagcatatg atatacattg ctatagatta ggatatggtg gaggatttta
    10381 tgatagattt ttagaaaact taagaaaaga tgctataact atcggcatag catttgactt
    10441 ccagatattc gattctattc caaaagaaac tcatgatgca caattagact acatagttac
    10501 tgaaactaga attatcactc caaataatta gaatattaag tatttccaga ccccatttaa
    10561 tatagtaata aatactactg ttaatatctt actttataag cattttaagt catggctttt
    10621 acaacaataa gaaccatata caatttactt acattaataa aaaccatgac tttattgtac
    10681 aatatgcagt tatttaatta taaaatacct tcttatttcg tcgcatttaa ttctattcta
    10741 tctggaagtt cactcatatt tgtttcaaca actatgtatg gaaaagaatc ttccttatct
    10801 ttatacttta tcttgactct caaaacatcc tttccttcct caaccacact ttctattttg
    10861 tccatttcta taccatattt attatttcct ctagtcacta taatgtatat tttgttatcg
    10921 attttagccg ctaatgctct ttcttcattt gtatacttat ccatcacatc taatatcttt
    10981 tctggtattg aatttctttg taatactgta taatctatgg gtttagattt ctctacaaac
    11041 atacttggta tgaatataaa tccccctata acgaatacaa gagctataac tccataaatt
    11101 atacctttaa tattaaactt tacattcaat cttatcactc ctcccatata ttctaaatat
    11161 atgatttata aacttatctt agactctaaa ttattgatta gtatatattt atacataatt
    11221 ataaatatat gtaatgtaac taaaaaacat gttttttcta tttcataata aacgagctaa
    11281 aaaataaaaa gagctatatg aaaacatttt cattgttttc atatagctct tgagtttaca
    11341 atattaaaaa atacttattt gtcactgatt ccttcttgat atccagatgt ttttgtaatc
    11401 tgtctataaa gaacacaaac cagtattatg acgcccatat atccagtata tggatataaa
    11461 ataccaacca gcttatcaaa tggtaggaag ccacctataa gacctaatat agctgctatt
    11521 aaagttatta atttaaactt aggatgttta tcatctacaa atctattagt tactgaccat
    11581 aataaaggta cagctgttgt atatatacct aatataagaa ttattgagaa taaaactcca
    11641 attactggtg aaatcttatc tgctaagaat aatgatggta ttgcttttga atataagttt
    11701 cctatatcag aaagaatagc taagtgcatc attatagctg cagccataag tgctactcca
    11761 cctaatatac caccacaaat agcttctttt ttgttagcag cacttgctcc taatccagtt
    11821 aagaatgcca taacaacaat tgtgttataa gtagtatata ttacaccaga tagataggca
    11881 tttggaactg gtttagctat ctttacagtg ctaagaactt gtgcagcttc tcctatatta
    11941 cctatgtttt tagctaaact tataccacca actaaaagtg taaagattat tattataggc
    12001 cctattccac ctagtatctt tgataattta tcaagaccta gtgaaacagt taataatgct
    12061 actactgcca tacctactct acctacaaat ggatttaatc catagtattc agttaaagtt
    12121 gctcctgctc ctgaaatcat tactacgaaa acaccaaata agaataaagg tccaaaccat
    12181 tcaaagaata ttcctaaata cttaccacaa taaacacgat aaattttgat aggttcttta
    12241 agttgaagct ctttaccttt tgacataact gaagcaccca tccatgagaa taataccatt
    12301 gaaattatcc caccaataat acctgcaaaa ccataaaaag agaagaattg cattatttcc
    12361 tgtcctgttg caaatccaga accgattact gttgctacat acgcacctgc gaaactgatg
    12421 actgttttaa catttacttt ttctgacata tctcagttac ctccccatgt gaaatttttt
    12481 cttctgatta aacaattcga taaactacct acaatttcct ttaacataaa atacatgata
    12541 actgttttat agctttttag tataataact taaaacttat aatctgattt tataccctac
    12601 tcctcctctc ataatttttt tagattcttt tatctaagta gtcattatat ataaaattag
    12661 tttctctata aattatatat tagtcatatt tttctgaata gtcaatatat atttgaatat
    12721 tttctctatt tttgtaaaaa tttgaatatt ttattacatt tttgatatat tgatatcata
    12781 taaaaaaaag agagatataa attaatataa cactttatac ctctctttta aatatattat
    12841 attattaaca aacatgaata atttatatct cttacattct ttttgcaata ataacttctt
    12901 taacagtctt tattatgtca tcacaagtta attcatattt ttttaacaat tcatttggag
    12961 taccagattc tccaaatgta tctttaattc caactttctt tacaatggtt ggacaagact
    13021 ctcctactac ctcacttaca gcagaaccta atcccccaat tatgctatgt tcttctacag
    13081 ttacaatagc attcgtttct tttgctgatt ctaatattaa atctttgtct ataggtttta
    13141 tcgaggacat gtttataact ctagcactta taccttcttc ttgcaacttt tcttgtgcta
    13201 atagagcttc atttaccata attccacaag ctataattga tacatccttt ccttctctta
    13261 agactgtacc ttttcctatt tcaaatttat aatcttcatc aaataaaact ggtactgaac
    13321 ttctccctaa tctaacataa acaggtccat tatacttagc tatttcaaaa ataatttttt
    13381 ctgtttcaac tccatcagct ggaacaagaa ctgtcatatt tggtatagct ctcattatag
    13441 caatatcttc cacactttca tgagatgctc catcctctcc aacagtaaga cctgcatgag
    13501 tagcacatat ttttacattt agctttggat aacaaactga atttcttata atctcaaaag
    13561 cccttcccgt agcaaacata gcaaaagtac ttgcaaaagg tattttacca gcagttgata
    13621 atccacaagc agcgcctatt aaattttgtt cagctatacc catattaaaa aatctatctg
    13681 gaaatgactt gtaaaaatca tgtgtttttg tagactttga taaatctgca tctaatacta
    13741 caacattgtc atttatttga cctaatttta ctaatgcttt accatatgct tctctcgtcg
    13801 ccattttact cattgtcagc acctcctaat tcaagcaaag ctttttctag ctcctcatca
    13861 cttggagctg tcccatgcca tcctgcttga ttttccataa aagatattcc tttgcctttt
    13921 atagtttttg caactatcat tgtaggtttt ttaactgttg atttagctat atcaagagcc
    13981 gcaaatattt ggtcaaaatc atgtccatct atctcaatta cattccaacc aaaagcttta
    14041 aatttatcaa ctattgaacc taaactcatt acgctttcta tatctccatc tatttgaagt
    14101 ccattattat ctaaaaaagc aattaaatta tcaagtttat aatgtgcagc actcatagca
    14161 gcttcccaaa caattccttc ttgaacctca ccatcaccaa gcaaagtata cacattccac
    14221 ggagcattat ccaactttga tgccatagcc ataccacatg caactgaaaa accttgacct
    14281 aaagaaccag tagatatttc cacacctggc gtgcctttca tgtctggatg accttgtaac
    14341 atccttccta tcttccttaa tccattcagt tcttccttat caaaatagcc tttttcagcc
    14401 aatgtagcat ataatgctgg tgcagcatgt ccttttgata atacaaatct atctctatcc
    14461 tccattttag gatttgaaga atccacattc atttcatcaa agtataacgc agtaagtatt
    14521 tcaactactg ataatgaccc tcctggatgt ccagatttgg ctctatgtat cattgaaact
    14581 atatctcttc ttatgatacg cgcaatctca tttaatcctt tatggtctct catgcaatta
    14641 cctcccttga gttcgtaatt ttatatcaat tccatattat tatatcactt ttatgctatt
    14701 tttttgcgtt atttttaatt ttattaacat agtacattaa aattaaacct taagagatat
    14761 ttaaaagaaa aaagggattg tctaataaaa gacaaatccc tctttaaaaa gtaaacaatc
    14821 ctaaacttat ttgaagtcca tcatctactt ttatcatcat attttcatct agacaaccaa
    14881 ttttttccct cagtctcttt ttatcgatag ttctaatttg ctctaaaaga attactgagt
    14941 ctttattaag cccatattca ttggaactta tctctacatg agtaggtaat ttggctttat
    15001 taatctgaga tgttatagct gatactataa ctgtaggact atatttatta cctacatcat
    15061 tttgtattat cagaacaggt ctaacgcctc cctgctctga accaacaact ggacttaaat
    15121 cagcgtaata taaatcacca cgctttattt cacaattagt actcaccttg ggcaatcttc
    15181 ccttcatttt tatcatcaga agatacttct tcaactgtca tacctaattc agctagtgac
    15241 agattaattt gacccatttc tctataaccc gttttcatag attctttaat atgaattttc
    15301 tttttctgag ttatatagaa ctgaaaagca gcttttgcaa aatcttctct gttactgttc
    15361 tccatctgaa ctatactatc aacttcagaa atcagagagt caggtaaagt aacttctatt
    15421 ttttctttac tcttatcgta cacaaaatcg cctcccagat tataatatca tggttttatt
    15481 ttagcaaata actgtttatt tgtacaagct cattattttc catataaaca cggtcaactc
    15541 ttcttgatat catacataac acttcatagt ttatagttcc taagtcttta gctatacgct
    15601 cagctgtaac ttcgccttct ccaaatagta taacctcatc tccaactttt atgtctatat
    15661 ctttgtcaat tctaaccatt atttgatcca tacatattct accaactaca tcaaacactt
    15721 ctcccttaat aagaaccttt ggattttttt ggattctagt aaatccatct gcgtatccta
    15781 ttggaactgt agctattgtt tctttacctg tagttgtgta ttttagtcca taacttattc
    15841 ctacacctgg ttcaacttgt tttatatgtc cgatttttga ttttaatttc atggctggtc
    15901 ttaattctaa tctatcttta aatacatcat cagatggata atgaccatat aatattattc
    15961 ctgctcttac catatttaat cttaaatcag ggcaatccat aatagctgca ctgtttgata
    16021 catgttttat agctattttt acaccagcct catctaattt atcagacata aatttataat
    16081 tattagcttg tttataagtg tactctttac ttacttcatc agctgtagca aaatgagtaa
    16141 acataccttc taaatctata tattctaatt tatttaattc tattatttcc tgtactgact
    16201 tctcattagg ttggaaacct attctagtca tccctgagtc tattttaaca tgaacacagg
    16261 ctttttctcc taaagatttt gcaatttcat ttatcttttg tgctgtttct aaagaataaa
    16321 ctgtcatagt tattttattt tttatagaat cttcaaaagc ttcgtctgga gtatatccca
    16381 agttcaaaat aggaagtgtt atgccatttt gtctaagttc aattccttca gcagttcttg
    16441 ctactgctaa gtaatctact ttttcttttt ctagcaattt tgcaacttct actgcaccat
    16501 gtccatatgc atcagctttt attactccac aaatcttaat atcttcttct aataaatttt
    16561 taatattatt taagttaaat cttaagttat ctagatttat ctctgcccat gtaggcactg
    16621 ttattttttg catgtcttta gtccccctta gtttctgtat tcaaaatctt tgtattttac
    16681 tgtaaatctt ggcactccct ctttatctaa cacttccatt ttttcaggat tttttgtgtc
    16741 agcatttaca tataatactt gcttgttaaa atatttatta tccccaggaa taaaagtctc
    16801 taaaaccaaa tgtcctttgg ataactttac tttcatctcc tcattttgaa gatagttttt
    16861 tataaagtct cctacaaaaa gatattgatt attttttcct gtattaggta actccactac
    16921 atcactaatc tttggatttt taactaatat tttatcatct tgatattcta tacttttccc
    16981 ttttaaatgt tttggggaaa ttacttctaa tttatagtta tcggtttttt tataagtatg
    17041 aattaaaaca taattgtgtg ggcttttatt tccaactact tctacttcag ctttacaact
    17101 gtaataattc atatcagaaa tctgcttttg aaaatctttg tatacttctt cttttgtgga
    17161 ctgtcgtttt tggcatccta ttacaattat aaccagtgcc aagaacataa tacatactat
    17221 ggtccacttt tttctcacat cacacctcct acttcagttt attcattgta taaagctttt
    17281 attatatcat atctacaaat tataccttta agtttgttgt catcatctac tacaggaact
    17341 ctgtttattg attttttaat cattacatta gctacatcat caaacttatc atcttcatga
    17401 acctttatta tatctttaga cataagttct ccaaccttat aagcagctac ttgttttata
    17461 tctttttcaa ctttttttaa gtcatctaag aaaatcaatc cttgtaatag atttatatag
    17521 agaggtgctt ctatatattt ttctttttta agaatatctg tttcagaaat tattccaaca
    17581 actctattct ctgaatctac aactggcaga cctcctattt tttctgcaat tagcatatta
    17641 gctacatctg ctatactatc atcttgtttt gctactatta catctgttgt cattatttct
    17701 tttgctgttt tatccatcat aatgtaatca ctccttagtc cttaattatg gttatcgcat
    17761 ttgctatagc ataatctttt gaatgtgata ttgaaacttt tatttctaaa acattataat
    17821 ctatgcacat ttttgctaga ttattataag tttttactat tggttttccc atttcatttc
    17881 tgagaacttc tatatcttta aaattaaaca atctaattcc tgtacctata gatttactta
    17941 tagcttcctt ggctgcgaaa ttacctgcta tactttctgc tttaaaattc ttagaattaa
    18001 aatactctat ttctctatct gtaaatatct tctccaaaaa cctattattt ttgtctacag
    18061 cctttcttat tctatcaatt tcaattatat ctacgccaat atcaaatata ttcattgttc
    18121 ctccagaaaa tttataatac ttctttcaat aattaataat gaatttataa atttactatc
    18181 gataatacac attattattt agtttatgtt acttatctta at
//
LOCUS       DAEHWO010000086        18153 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEHWO010000086 DAEHWO010000000
VERSION     DAEHWO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18153
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.086"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            357..7457
                     /gene="tcdB"
                     /locus_tag="KNP54_003252"
                     /gene_synonym="toxB"
     CDS             357..7457
                     /gene="tcdB"
                     /locus_tag="KNP54_003252"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBF0894116.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            7579..8079
                     /gene="tcdE"
                     /locus_tag="KNP54_003253"
     CDS             7579..8079
                     /gene="tcdE"
                     /locus_tag="KNP54_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBF0894117.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8158..8319
                     /locus_tag="KNP54_003254"
     CDS             8158..8319
                     /locus_tag="KNP54_003254"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894118.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            8384..8590
                     /locus_tag="KNP54_003255"
     CDS             8384..8590
                     /locus_tag="KNP54_003255"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894119.1"
                     /translation="MKLFKNTKIRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKT
                     LKKYKICLQITIRQSPYLIEESIN"
     gene            8807..16939
                     /gene="tcdA"
                     /locus_tag="KNP54_003256"
                     /gene_synonym="toxA"
     CDS             8807..16939
                     /gene="tcdA"
                     /locus_tag="KNP54_003256"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBF0894120.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17274..17972)
                     /gene="tcdC"
                     /locus_tag="KNP54_003257"
     CDS             complement(17274..17972)
                     /gene="tcdC"
                     /locus_tag="KNP54_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBF0894121.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
BASE COUNT         7168 a         2028 c         2818 g         6139 t
ORIGIN      
        1 aaaataaaaa aagactatga aaattatttt aacttgtaat taatgagttt aaagaaatat
       61 ttacaataga aatcaaattt tataattaac tttattgtaa aattaataac ttaatctaag
      121 aatatcttaa tttttatatt ttatatagaa caatgtttac atatttattt cagacaacgt
      181 ctttattcaa tcgaagagca aattaatcaa ctgagtgtct taaatttaaa atgttaggaa
      241 gtgaatgtat atgaaaacct aagtagatat tagtatattt tataaataga aaggaggata
      301 tataaaagag ttttagcatt tagatgtaaa aatattatag taaaggagaa aattttatga
      361 gtttagttaa tagaaaacag ttagaaaaaa tggcaaatgt aagatttcgt actcaagaag
      421 atgaatatgt tgcaatattg gatgctttag aagaatatca taatatgtca gagaatactg
      481 tagtcgaaaa atatttaaaa ttaaaagata taaatagttt aacagatatt tatatagata
      541 catataaaaa atctggtaga aataaagcct taaaaaaatt taaggaatat ctagttacag
      601 aagtattaga gctaaagaat aataatttaa ctccagttga gaaaaattta cattttgttt
      661 ggattggagg tcaaataaat gacactgcta ttaattatat aaatcaatgg aaagatgtaa
      721 atagtgatta taatgttaat gttttttatg atagtaatgc atttttgata aacacattga
      781 aaaaaactgt agtagaatca gcaataaatg atacacttga atcatttaga gaaaacttaa
      841 atgaccctag atttgactat aataaattct tcagaaaacg tatggaaata atttatgata
      901 aacagaaaaa tttcataaac tactataaag ctcaaagaga agaaaatcct gaacttataa
      961 ttgatgatat tgtaaagaca tatctttcaa atgagtattc aaaggagata gatgaactta
     1021 atacctatat tgaagaatcc ttaaataaaa ttacacagaa tagtggaaat gatgttagaa
     1081 actttgaaga atttaaaaat ggagagtcat tcaacttata tgaacaagag ttggtagaaa
     1141 ggtggaattt agctgctgct tctgacatat taagaatatc tgcattaaaa gaaattggtg
     1201 gtatgtattt agatgttgat atgttaccag gaatacaacc agacttattt gagtctatag
     1261 agaaacctag ttcagtaaca gtggattttt gggaaatgac aaagttagaa gctataatga
     1321 aatacaaaga atatatacca gaatatacct cagaacattt tgacatgtta gacgaagaag
     1381 ttcaaagtag ttttgaatct gttctagctt ctaagtcaga taaatcagaa atattctcat
     1441 cacttggtga tatggaggca tcaccactag aagttaaaat tgcatttaat agtaagggta
     1501 ttataaatca agggctaatt tctgtgaaag actcatattg tagcaattta atagtaaaac
     1561 aaatcgagaa tagatataaa atattgaata atagtttaaa tccagctatt agcgaggata
     1621 atgattttaa tactacaacg aataccttta ttgatagtat aatggctgaa gctaatgcag
     1681 ataatggtag atttatgatg gaactaggaa agtatttaag agttggtttc ttcccagatg
     1741 ttaaaactac tattaactta agtggccctg aagcatatgc ggcagcttat caagatttat
     1801 taatgtttaa agaaggcagt atgaatatcc atttgataga agctgattta agaaactttg
     1861 aaatctctaa aactaatatt tctcaatcaa ctgaacaaga aatggctagc ttatggtcat
     1921 ttgacgatgc aagagctaaa gctcaatttg aagaatataa aaggaattat tttgaaggtt
     1981 ctcttggtga agatgataat cttgattttt ctcaaaatat agtagttgac aaggagtatc
     2041 ttttagaaaa aatatcttca ttagcaagaa gttcagagag aggatatata cactatattg
     2101 ttcagttaca aggagataaa attagttatg aagcagcatg taacttattt gcaaagactc
     2161 cttatgatag tgtactattt cagaaaaata tagaagattc agaaattgca tattattata
     2221 atcctggaga tggtgaaata caagaaatag acaagtataa aattccaagt ataatttctg
     2281 atagacctaa gattaaatta acatttattg gtcatggtaa agatgaattt aatactgata
     2341 tatttgcagg ttttgatgta gattcattat ccacagaaat agaagcagca atagatttag
     2401 ctaaagagga tatttctcct aagtcaatag aaataaattt attaggatgt aatatgttta
     2461 gctactctat caacgtagag gagacttatc ctggaaaatt attacttaaa gttaaagata
     2521 aaatatcaga attaatgcca tctataagtc aagactctat tatagtaagt gcaaatcaat
     2581 atgaagttag aataaatagt gaaggaagaa gagaattatt ggatcattct ggtgaatgga
     2641 taaataaaga agaaagtatt ataaaggata tttcatcaaa agaatatata tcatttaatc
     2701 ctaaagaaaa taaaattaca gtaaaatcta aaaatttacc tgagctatct acattattac
     2761 aagaaattag aaataattct aattcaagtg atattgaact agaagaaaaa gtaatgttaa
     2821 cagaatgtga gataaatgtt atttcaaata tagatacgca aattgttgag gaaaggattg
     2881 aagaagctaa gaatttaact tctgactcta ttaattatat aaaagatgaa tttaaactaa
     2941 tagaatctat ttctgatgca ctatgtgact taaaacaaca gaatgaatta gaagattctc
     3001 attttatatc ttttgaggac atatcagaga ctgatgaggg atttagtata agatttatta
     3061 ataaagaaac tggagaatct atatttgtag aaactgaaaa aacaatattc tctgaatatg
     3121 ctaatcatat aactgaagag atttctaaga taaaaggtac tatatttgat actgtaaatg
     3181 gtaagttagt aaaaaaagta aatttagata ctacacacga agtaaatact ttaaatgctg
     3241 cattttttat acaatcatta atagaatata atagttctaa agaatctctt agtaatttaa
     3301 gtgtagcaat gaaagtccaa gtttacgctc aattatttag tactggttta aatactatta
     3361 cagatgcagc caaagttgtt gaattagtat caactgcatt agatgaaact atagacttac
     3421 ttcctacatt atctgaagga ttacctataa ttgcaactat tatagatggt gtaagtttag
     3481 gtgcagcaat caaagagcta agtgaaacga gtgacccatt attaagacaa gaaatagaag
     3541 ctaagatagg tataatggca gtaaatttaa caacagctac aactgcaatc attacttcat
     3601 ctttgggggt agctagtgga tttagtatac ttttagttcc tttagcagga atttcagcag
     3661 gtataccaag cttagtaaac aatgaacttg tacttcgaga taaggcaaca aaggttgtag
     3721 attattttaa acatgtttca ttagttgaaa ctgaaggagt atttacttta ttagatgata
     3781 aaataatgat gccacaagat gatttagtga tatcagaaat agattttaat aataattcaa
     3841 tagttttagg taaatgtgaa atctggagaa tggaaggtgg ttcaggtcat actgtaactg
     3901 atgatataga tcacttcttt tcagcaccat caataacata tagagagcca cacttatcta
     3961 tatatgacgt attggaagta caaaaagaag aacttgattt gtcaaaagat ttaatggtat
     4021 tacctaatgc tccaaataga gtatttgctt gggaaacagg atggacacca ggtttaagaa
     4081 gcttagaaaa tgatggcaca aaactgttag accgtataag agataactat gaaggtgagt
     4141 tttattggag atattttgct tttatagctg atgctttaat aacaacatta aaaccaagat
     4201 atgaagatac taatataaga ataaatttag atagtaatac tagaagtttt atagttccaa
     4261 taataactac agaatatata agagaaaaat tatcatattc tttctatggt tcaggaggaa
     4321 cttatgcatt gtctctttct caatataata tgggtataaa tatagaatta agtgaaagtg
     4381 atgtttggat tatagatgtt gataatgttg tgagagatgt aactatagaa tctgataaaa
     4441 ttaaaaaagg tgatttaata gaaggtattt tatctacact aagtattgaa gagaataaaa
     4501 ttatcttaaa tagccatgag attaattttt ctggtgaggt aaatggaagt aatggatttg
     4561 tttctttaac attttcaatt ttagaaggaa taaatgcaat tatagaagtt gatttattat
     4621 ctaaatcata taaattactt atttctggcg aattaaaaat attgatgtta aattcaaatc
     4681 atattcaaca gaaaatagat tatataggat tcaatagcga attacagaaa aatataccat
     4741 atagctttgt agatagtgaa ggaaaagaga atggttttat taatggttca acaaaagaag
     4801 gtttatttgt atctgaatta cctgatgtag ttcttataag taaggtttat atggatgata
     4861 gtaagccttc atttggatat tatagtaata atttgaaaga tgtcaaagtt ataactaaag
     4921 ataatgttaa tatattaaca ggttattatc ttaaggatga tataaaaatc tctctttctt
     4981 tgactctaca agatgaaaaa actataaagt taaatagtgt gcatttagat gaaagtggag
     5041 tagctgagat tttgaagttc atgaatagaa aaggtaatac aaatacttca gattctttaa
     5101 tgagcttttt agaaagtatg aatataaaaa gtattttcgt taatttctta caatctaata
     5161 ttaagtttat attagatgct aattttataa taagtggtac tacttctatt ggccaatttg
     5221 agtttatttg tgatgaaaat gataatatac aaccatattt cattaagttt aatacactag
     5281 aaactaatta tactttatat gtaggaaata gacaaaatat gatagtggaa ccaaattatg
     5341 atttagatga ttctggagat atatcttcaa ctgttatcaa tttctctcaa aagtatcttt
     5401 atggaataga cagttgtgtt aataaagttg taatttcacc aaatatttat acagatgaaa
     5461 taaatataac gcctgtatat gaaacaaata atacttatcc agaagttatt gtattagatg
     5521 caaattatat aaatgaaaaa ataaatgtta atatcaatga tctatctata cgatatgtat
     5581 ggagtaatga tggtaatgat tttattctta tgtcaactag tgaagaaaat aaggtgtcac
     5641 aagttaaaat aagattcgtt aatgttttta aagataagac tttggcaaat aagctatctt
     5701 ttaactttag tgataaacaa gatgtacctg taagtgaaat aatcttatca tttacacctt
     5761 catattatga ggatggattg attggctatg atttgggtct agtttcttta tataatgaga
     5821 aattttatat taataacttt ggaatgatgg tatctggatt aatatatatt aatgattcat
     5881 tatattattt taaaccacca gtaaataatt tgataactgg atttgtgact gtaggcgatg
     5941 ataaatacta ctttaatcca attaatggtg gagctgcttc aattggagag acaataattg
     6001 atgacaaaaa ttattatttc aaccaaagtg gagtgttaca aacaggtgta tttagtacag
     6061 aagatggatt taaatatttt gccccagcta atacacttga tgaaaaccta gaaggagaag
     6121 caattgattt tactggaaaa ttaattattg acgaaaatat ttattatttt gatgataatt
     6181 atagaggagc tgtagaatgg aaagaattag atggtgaaat gcactatttt agcccagaaa
     6241 caggtaaagc ttttaaaggt ctaaatcaaa taggtgatta taaatactat ttcaattctg
     6301 atggagttat gcaaaaagga tttgttagta taaatgataa taaacactat tttgatgatt
     6361 ctggtgttat gaaagtaggt tacactgaaa tagatggcaa gcatttctac tttgctgaaa
     6421 acggagaaat gcaaatagga gtatttaata cagaagatgg atttaaatat tttgctcatc
     6481 ataatgaaga tttaggaaat gaagaaggtg aagaaatctc atattctggt atattaaatt
     6541 tcaataataa aatttactat tttgatgatt catttacagc tgtagttgga tggaaagatt
     6601 tagaggatgg ttcaaagtat tattttgatg aagatacagc agaagcatat ataggtttgt
     6661 cattaataaa tgatggtcaa tattatttta atgatgatgg aattatgcaa gttggatttg
     6721 tcactataaa tgataaagtc ttctacttct ctgactctgg aattatagaa tctggagtac
     6781 aaaacataga tgacaattat ttctatatag atgataatgg tatagttcaa attggtgtat
     6841 ttgatacttc agatggatat aaatattttg cacctgctaa tactgtaaat gataatattt
     6901 acggacaagc agttgaatat agtggtttag ttagagttgg ggaagatgta tattattttg
     6961 gagaaacata tacaattgag actggatgga tatatgatat ggaaaatgaa agtgataaat
     7021 attatttcaa tccagaaact aaaaaagcat gcaaaggtat taatttaatt gatgatataa
     7081 aatattattt tgatgagaag ggcataatga gaacgggtct tatatcattt gaaaataata
     7141 attattactt taatgagaat ggtgaaatgc aatttggtta tataaatata gaagataaga
     7201 tgttctattt tggtgaagat ggtgtcatgc agattggagt atttaataca ccagatggat
     7261 ttaaatactt tgcacatcaa aatactttgg atgagaattt tgagggagaa tcaataaact
     7321 atactggttg gttagattta gatgaaaaga gatattattt tacagatgaa tatattgcag
     7381 caactggttc agttattatt gatggtgagg agtattattt tgatcctgat acagctcaat
     7441 tagtgattag tgaatagata aaaatatgtt aaatatatcc tcttatactt aaatatataa
     7501 aaataaacaa aatgatacac tacataaagt gttctatcta atatgaagat ttaccaataa
     7561 aaaggtggac tatgatgaat gcacagtagt tcaccttttt atatttctaa tggtaacaaa
     7621 atattttttt atataaacct aggaggcgtt atgaatatga caatatcttt tttatcagag
     7681 catatattta taaagttagt aattttaact atatcatttg atacattatt aggatgttta
     7741 agtgcaataa aaagtcgtaa atttaattct agttttggaa tagatggagg aatcagaaaa
     7801 gtagcaatga tagcatgtat atttttttta tcagtagttg acattcttac aaagtttaac
     7861 tttttattta tgttaccaca agattgtatc aattttttaa gactaaaaca tcttggaata
     7921 tctgaatttt tctctatttt atttatttta tatgaaagtg taagtatatt aaaaaatatg
     7981 tgcttatgtg gattaccagt acctaagaga ttaaaggaaa aaatagcaat tttactagat
     8041 gcaatgacag atgaaatgaa tgctaaggat gaaaagtaag taatggtaga tataataaag
     8101 atattaacaa ataaaaagtg ttatccaaat aagaatagct gaaagttatc ataattcatg
     8161 aaactaataa tgaaaacgag ggagcagatg ccaagagaca cacaagtatt aaatacatat
     8221 aatttcgaag caagtgttca ttactatata gatgacaagg tagtatatca aacattggtt
     8281 cacaaagatg gtgcatggtc agttggtaaa atctattaag ctacattagt tacagatatc
     8341 acaaactata atagttaaac atagaaatat gtgtaaattg tgattgaaat tattcaaaaa
     8401 cacaaaaata cgtgatgaag gacaaaatga tatagaaaat aagtatcaaa ccttaataaa
     8461 tgatttaatt gatagtttaa aagttatagg aaaaatatat aaagaaataa aaacattaaa
     8521 aaaatataag atatgtttac aaattactat cagacaatct ccttatctaa tagaagagtc
     8581 aattaactaa ttgagtatct ttaaattgaa atgttaggaa gtgatttaaa tatgaaaact
     8641 taaattataa aaaatcaata ttaatttatt tttaaaaaat agaaaggagt gtataagatt
     8701 tattttcaaa gtttaaaaac aagaaaatca atttaaattt cagaaggaat aaatgtggtt
     8761 atagaagtgg atttattatc aaaaataata atactaggag gtttttatgt ctttaatatc
     8821 taaagaagag ttaataaaac tcgcatatag cattagacca agagaaaatg agtataaaac
     8881 tatactaact aatttagacg aatataataa gttaactaca aacaataatg aaaataaata
     8941 tttacaatta aaaaaactaa atgaatcaat tgatgttttt atgaataaat ataaaacttc
     9001 aagcagaaat agagcactct ctaatctaaa aaaagatata ttaaaagaag taattcttat
     9061 taaaaattcc aatacaagcc ctgtagaaaa aaatttacat tttgtatgga taggtggaga
     9121 agtcagtgat attgctcttg aatacataaa acaatgggct gatattaatg cagaatataa
     9181 tattaaactg tggtatgata gtgaagcatt cttagtaaat acactaaaaa aggctatagt
     9241 tgaatcttct accactgaag cattacagct actagaggaa gagattcaaa atcctcaatt
     9301 tgataatatg aaattttaca aaaaaaggat ggaatttata tatgatagac aaaaaaggtt
     9361 tataaattat tataaatctc aaatcaataa acctacagta cctacaatag atgatattat
     9421 aaagtctcat ctagtatctg aatataatag agatgaaact gtattagaat catatagaac
     9481 aaattctttg agaaaaataa atagtaatca tgggatagat atcagggcta atagtttgtt
     9541 tacagaacaa gagttattaa atatttatag tcaggagttg ttaaatcgtg gaaatttagc
     9601 tgcagcatct gacatagtaa gattattagc cctaaaaaat tttggcggag tatatttaga
     9661 tgttgatatg cttccaggta ttcactctga tttatttaaa acaatatcta gacctagctc
     9721 tattggacta gaccgttggg aaatgataaa attagaggct attatgaagt ataaaaaata
     9781 tataaataat tatacatcag aaaactttga taaacttgat caacaattaa aagataattt
     9841 taaactcatt atagaaagta aaagtgaaaa atctgagata ttttctaaat tagaaaattt
     9901 aaatgtatct gatcttgaaa ttaaaatagc tttcgcttta ggcagtgtta taaatcaagc
     9961 cttgatatca aaacaaggtt catatcttac taacctagta atagaacaag taaaaaatag
    10021 atatcaattt ttaaaccaac accttaaccc agccatagag tctgataata acttcacaga
    10081 tactactaaa atttttcatg attcattatt taattcagct accgcagaaa actctatgtt
    10141 tttaacaaaa atagcaccat acttacaagt aggttttatg ccagaagctc gctccacaat
    10201 aagtttaagt ggtccaggag cttatgcgtc agcttactat gatttcataa atttacaaga
    10261 aaatactata gaaaaaactt taaaagcatc agatttaata gaatttaaat tcccagaaaa
    10321 taatctatct caattgacag aacaagaaat aaatagtcta tggagctttg atcaagcaag
    10381 tgcaaaatat caatttgaga aatatgtaag agattatact ggtggatctc tttctgaaga
    10441 caatggggta gactttaata aaaatactgc cctcgacaaa aactatttat taaataataa
    10501 aattccatca aacaatgtag aagaagctgg aagtaaaaat tatgttcatt atatcataca
    10561 gttacaagga gatgatataa gttatgaagc aacatgcaat ttattttcta aaaatcctaa
    10621 aaatagtatt attatacaac gaaatatgaa tgaaagtgca aaaagctact ttttaagtga
    10681 tgatggagaa tctattttag aattaaataa atataggata cctgaaagat taaaaaataa
    10741 ggaaaaagta aaagtaacct ttattggaca tggtaaagat gaattcaaca caagcgaatt
    10801 tgctagatta agtgtagatt cactttccaa tgagataagt tcatttttag ataccataaa
    10861 attagatata tcacctaaaa atgtagaagt aaacttactt ggatgtaata tgtttagtta
    10921 tgattttaat gttgaagaaa cttatcctgg gaagttgcta ttaagtatta tggacaaaat
    10981 tacttccact ttacctgatg taaataaaaa ttctattact ataggagcaa atcaatatga
    11041 agtaagaatt aatagtgagg gaagaaaaga acttctggct cactcaggta aatggataaa
    11101 taaagaagaa gctattatga gcgatttatc tagtaaagaa tacatttttt ttgattctat
    11161 agataataag ctaaaagcaa agtccaagaa tattccagga ttagcatcaa tatcagaaga
    11221 tataaaaaca ttattacttg atgcaagtgt tagtcctgat acaaaattta ttttaaataa
    11281 tcttaagctt aatattgaat cttctattgg tgattacatt tattatgaaa aattagagcc
    11341 tgttaaaaat ataattcaca attctataga tgatttaata gatgagttca atctacttga
    11401 aaatgtatct gatgaattat atgaattaaa aaaattaaat aatctagatg agaagtattt
    11461 aatatctttt gaagatatct caaaaaataa ttcaacttac tctgtaagat ttattaacaa
    11521 aagtaatggt gagtcagttt atgtagaaac agaaaaagaa attttttcaa aatatagcga
    11581 acatattaca aaagaaataa gtactataaa gaatagtata attacagatg ttaatggtaa
    11641 tttattggat aatatacagt tagatcatac ttctcaagtt aatacattaa acgcagcatt
    11701 ctttattcaa tcattaatag attatagtag caataaagat gtactgaatg atttaagtac
    11761 ctcagttaag gttcaacttt atgctcaact atttagtaca ggtttaaata ctatatatga
    11821 ctctatccaa ttagtaaatt taatatcaaa tgcagtaaat gatactataa atgtactacc
    11881 tacaataaca gaggggatac ctattgtatc tactatatta gacggaataa acttaggtgc
    11941 agcaattaag gaattactag acgaacatga cccattacta aaaaaagaat tagaagctaa
    12001 ggtgggtgtt ttagcaataa atatgtcatt atctatagct gcaactgtag cttcaattgt
    12061 tggaataggt gctgaagtta ctattttctt attacctata gctggtatat ctgcaggaat
    12121 accttcatta gttaataatg aattaatatt gcatgataag gcaacttcag tggtaaacta
    12181 ttttaatcat ttgtctgaat ctaaaaaata tggccctctt aaaacagaag atgataaaat
    12241 tttagttcct attgatgatt tagtaatatc agaaatagat tttaataata attcgataaa
    12301 actaggaaca tgtaatatat tagcaatgga ggggggatca ggacacacag tgactggtaa
    12361 tatagatcac tttttctcat ctccatctat aagttctcat attccttcat tatcaattta
    12421 ttctgcaata ggtatagaaa cagaaaatct agatttttca aaaaaaataa tgatgttacc
    12481 taatgctcct tcaagagtgt tttggtggga aactggagca gttccaggtt taagatcatt
    12541 ggaaaatgac ggaactagat tacttgattc aataagagat ttatacccag gtaaatttta
    12601 ctggagattc tatgcttttt tcgattatgc aataactaca ttaaaaccag tttatgaaga
    12661 cactaatatt aaaattaaac tagataaaga tactagaaac ttcataatgc caactataac
    12721 tactaacgaa attagaaaca aattatctta ttcatttgat ggagcaggag gaacttactc
    12781 tttattatta tcttcatatc caatatcaac gaatataaat ttatctaaag atgatttatg
    12841 gatatttaat attgataatg aagtaagaga aatatctata gaaaatggta ctattaaaaa
    12901 aggaaagtta ataaaagatg ttttaagtaa aattgatata aataaaaata aacttattat
    12961 aggcaatcaa acaatagatt tttcaggcga tatagataat aaagatagat atatattctt
    13021 gacttgtgag ttagatgata aaattagttt aataatagaa ataaatcttg ttgcaaaatc
    13081 ttatagtttg ttattgtctg gggataaaaa ttatttgata tccaatttat ctaatactat
    13141 tgagaaaatc aatactttag gcctagatag taaaaatata gcgtacaatt acactgatga
    13201 atctaataat aaatattttg gagctatatc taaaacaagt caaaaaagca taatacatta
    13261 taaaaaagac agtaaaaata tattagaatt ttataatgac agtacattag aatttaacag
    13321 taaagatttt attgctgaag atataaatgt atttatgaaa gatgatatta atactataac
    13381 aggaaaatac tatgttgata ataatactga taaaagtata gatttctcta tttctttagt
    13441 tagtaaaaat caagtaaaag taaatggatt atatttaaat gaatccgtat actcatctta
    13501 ccttgatttt gtgaaaaatt cagatggaca ccataatact tctaatttta tgaatttatt
    13561 tttggacaat ataagtttct ggaaattgtt tgggtttgaa aatataaatt ttgtaatcga
    13621 taaatacttt acccttgttg gtaaaactaa tcttggatat gtagaattta tttgtgacaa
    13681 taataaaaat atagatatat attttggtga atggaaaaca tcgtcatcta aaagcactat
    13741 atttagcgga aatggtagaa atgttgtagt agagcctata tataatcctg atacgggtga
    13801 agatatatct acttcactag atttttccta tgaacctctc tatggaatag atagatatat
    13861 caataaagta ttgatagcac ctgatttata tacaagttta ataaatatta ataccaatta
    13921 ttattcaaat gagtactacc ctgagattat agttcttaac ccaaatacat tccacaaaaa
    13981 agtaaatata aatttagata gttcttcttt tgagtataaa tggtctacag aaggaagtga
    14041 ctttatttta gttagatact tagaagaaag taataaaaaa atattacaaa aaataagaat
    14101 caaaggtatc ttatctaata ctcaatcatt taataaaatg agtatagatt ttaaagatat
    14161 taaaaaacta tcattaggat atataatgag taattttaaa tcatttaatt ctgaaaatga
    14221 attagataga gatcatttag gatttaaaat aatagataat aaaacttatt actatgatga
    14281 agatagtaaa ttagttaaag gattaatcaa tataaataat tcattattct attttgatcc
    14341 tatagaattt aacttagtaa ctggatggca aactatcaat ggtaaaaaat attattttga
    14401 tataaatact ggagcagctt taactagtta taaaattatt aatggtaaac acttttattt
    14461 taataatgat ggtgtgatgc agttgggagt atttaaagga cctgatggat ttgaatattt
    14521 tgcacctgcc aatactcaaa ataataacat agaaggtcag gctatagttt atcaaagtaa
    14581 attcttaact ttgaatggca aaaaatatta ttttgataat gactcaaaag cagtcactgg
    14641 atggagaatt attaacaatg agaaatatta ctttaatcct aataatgcta ttgctgcagt
    14701 cggattgcaa gtaattgaca ataataagta ttatttcaat cctgacactg ctatcatctc
    14761 aaaaggttgg cagactgtta atggtagtag atactacttt gatactgata ccgctattgc
    14821 ctttaatggt tataaaacta ttgatggtaa acacttttat tttgatagtg attgtgtagt
    14881 gaaaataggt gtgtttagta cctctaatgg atttgaatat tttgcacctg ctaatactta
    14941 taataataac atagaaggtc aggctatagt ttatcaaagt aaattcttaa ctttgaatgg
    15001 taaaaaatat tactttgata ataactcaaa agcagttacc ggatggcaaa ctattgatag
    15061 taaaaaatat tactttaata ctaacactgc tgaagcagct actggatggc aaactattga
    15121 tggtaaaaaa tattacttta atactaacac tgctgaagca gctactggat ggcaaactat
    15181 tgatggtaaa aaatattact ttaatactaa cactgctata gcttcaactg gttatacaat
    15241 tattaatggt aaacattttt attttaatac tgatggtatt atgcagatag gagtgtttaa
    15301 aggacctaat ggatttgaat attttgcacc tgctaatacg gatgctaaca acatagaagg
    15361 tcaagctata ctttaccaaa atgaattctt aactttgaat ggtaaaaaat attactttgg
    15421 tagtgactca aaagcagtta ctggatggag aattattaac aataagaaat attactttaa
    15481 tcctaataat gctattgctg caattcatct atgcactata aataatgaca agtattactt
    15541 tagttatgat ggaattcttc aaaatggata tattactatt gaaagaaata atttctattt
    15601 tgatgctaat aatgaatcta aaatggtaac aggagtattt aaaggaccta atggatttga
    15661 gtattttgca cctgctaata ctcacaataa taacatagaa ggtcaggcta tagtttacca
    15721 gaacaaattc ttaactttga atggcaaaaa atattatttt gataatgact caaaagcagt
    15781 tactggatgg caaaccattg atggtaaaaa atattacttt aatcttaaca ctgctgaagc
    15841 agctactgga tggcaaacta ttgatggtaa aaaatattac tttaatctta acactgctga
    15901 agcagctact ggatggcaaa ctattgatgg taaaaaatat tactttaata ctaacacttt
    15961 catagcctca actggttata caagtattaa tggtaaacat ttttatttta atactgatgg
    16021 tattatgcag ataggagtgt ttaaaggacc taatggattt gaatactttg cacctgctaa
    16081 tactcataat aataacatag aaggtcaagc tatactttac caaaataaat tcttaacttt
    16141 gaatggtaaa aaatattact ttggtagtga ctcaaaagca gttaccggat tgcgaactat
    16201 tgatggtaaa aaatattact ttaatactaa cactgctgtt gcagttactg gatggcaaac
    16261 tattaatggt aaaaaatact actttaatac taacacttct atagcttcaa ctggttatac
    16321 aattattagt ggtaaacatt tttattttaa tactgatggt attatgcaga taggagtgtt
    16381 taaaggacct gatggatttg aatactttgc acctgctaat acagatgcta acaatataga
    16441 aggtcaagct atacgttatc aaaatagatt cctatattta catgacaata tatattattt
    16501 tggtaataat tcaaaagcgg ctactggttg ggtaactatt gatggtaata gatattactt
    16561 cgagcctaat acagctatgg gtgcgaatgg ttataaaact attgataata aaaattttta
    16621 ctttagaaat ggtttacctc agataggagt gtttaaaggg tctaatggat ttgaatactt
    16681 tgcacctgct aatacggatg ctaacaatat agaaggtcaa gctatacgtt atcaaaatag
    16741 attcctacat ttacttggaa aaatatatta ctttggtaat aattcaaaag cagttactgg
    16801 atggcaaact attaatggta aagtatatta ctttatgcct gatactgcta tggctgcagc
    16861 tggtggactt ttcgagattg atggtgttat atatttcttt ggtgttgatg gagtaaaagc
    16921 ccctgggata tatggctaaa atatatgttt gataaaaaat tattcctgtg ctactaagaa
    16981 attattttta tataataaat attgagattt aattaaaagt catgtgttat tgtaatacat
    17041 gacttttagt taaaattttt ctatcattta ataatctatt attcttgact attttataat
    17101 aaaattcata tatggaaata ttaatactaa ataattaata gttgataaaa aatagataat
    17161 atgctaaaag caaaaactaa tttagagcct tgtaactgtt tatttgcaat tataaaaaca
    17221 tctttaaaca tattgactat aatataaaat attaactata atacaaaaca atattaatta
    17281 attttctcta cagctatccc tggtatagtt atatttccac ccatagttga ttcataagtt
    17341 atagttccag cacttatacc tcttatagtt atgtaatcat cctctaatac tcttgaagga
    17401 gttattgatt ttttataact acatagtaca accttatcat aatttccaga cacagctaat
    17461 cttatttgca cctcatcacc atcttcaata acttgaataa ccttaccttc aaattttacc
    17521 tttttgtact tataatcatc aggtgttcta gctaattggt cataagtaat accagtatca
    17581 tatcctttct tctcctcttc ttcttttttg cgttgttctt cagccttttt agcttcttca
    17641 gcttttttag cttcttcagc tttacgttga ttttcagctt caatagcttt cttttcgtcg
    17701 tctttcattt tgaaccatgg ttcagcatca gacaatttgc tatttaaagt ttctatttct
    17761 gttttttgag aatctataac tgatgtttgg ttagaaatga cctcctcatg gtcttcagaa
    17821 caagctggtg aggatatatt gccaaaaaac acgcctaaaa taaatgccag tagagcaata
    17881 ccctttgtgc tcttaaagaa tttaattatt ttcttagagc ttccttttcc ttcattacta
    17941 aattcgttac cctcattttt tttagaaaac ataatacaat ctccctttta ttagatatat
    18001 tttattttaa aagttaaaaa cttaaaataa ctagttgact aaaaattata tattcatatt
    18061 ttcctaaaat atatttcccc taagcataat tttacaaaat aaagtaagaa gattcaatat
    18121 attttgaaaa aataagataa aaatgtcaga tta
//
LOCUS       DAEHWO010000087        18053 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEHWO010000087 DAEHWO010000000
VERSION     DAEHWO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18053
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.087"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            487..1347
                     /locus_tag="KNP54_003258"
     CDS             487..1347
                     /locus_tag="KNP54_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0894122.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKTLNIKASDYLSLTLLDHLEF
                     LLKRCKKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSE
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1337..3208
                     /locus_tag="KNP54_003259"
     CDS             1337..3208
                     /locus_tag="KNP54_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0894123.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQSTTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3228..4682
                     /locus_tag="KNP54_003260"
     CDS             3228..4682
                     /locus_tag="KNP54_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBF0894124.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYEMPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLGKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5707..6915
                     /locus_tag="KNP54_003261"
     CDS             5707..6915
                     /locus_tag="KNP54_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894125.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            6946..8325
                     /locus_tag="KNP54_003262"
     CDS             6946..8325
                     /locus_tag="KNP54_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0894126.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8431..9621
                     /locus_tag="KNP54_003263"
     CDS             8431..9621
                     /locus_tag="KNP54_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0894127.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIREETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEVLLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9749..11077)
                     /locus_tag="KNP54_003264"
     CDS             complement(9749..11077)
                     /locus_tag="KNP54_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894128.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCIGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(11695..12909)
                     /locus_tag="KNP54_003265"
     CDS             complement(11695..12909)
                     /locus_tag="KNP54_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBF0894129.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            13335..14051
                     /locus_tag="KNP54_003266"
     CDS             13335..14051
                     /locus_tag="KNP54_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBF0894130.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            14186..14812
                     /locus_tag="KNP54_003267"
     CDS             14186..14812
                     /locus_tag="KNP54_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBF0894131.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(15012..16556)
                     /locus_tag="KNP54_003268"
     CDS             complement(15012..16556)
                     /locus_tag="KNP54_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0894132.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(16582..17223)
                     /locus_tag="KNP54_003269"
     CDS             complement(16582..17223)
                     /locus_tag="KNP54_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBF0894133.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            17493..17684
                     /locus_tag="KNP54_003270"
                     /pseudo
     CDS             17493..17684
                     /locus_tag="KNP54_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
BASE COUNT         6681 a         2131 c         2994 g         6247 t
ORIGIN      
        1 tttaaatgaa actaaatttg aagctttacc tattaatata tcttaatagt gattaaataa
       61 aactaaactt aagactttat atgttaatat atcttaagaa tttatttgtt aaaatacagt
      121 tcattatatt taaaagcatt actatgataa ttcataatag taaaatagat aatggttcag
      181 acaatattat aaatactagt gacggtaaaa tagtatcaat ttagtatata aaccttgtca
      241 gataatcgca taacagagct tgtagttata gaataaaaaa atatctagga aaccgttgac
      301 agatttatat ggatagtata acatatagaa tatgaaatta aacaaaaaag aattttaatt
      361 atggcgacgt agtcataatt ttgagtatgt tactgattag caggcagaac tcaagtatat
      421 atgtgaaaaa tagagggata ctctatacat atatgcttga gttcttttta ttgaagggag
      481 gaatatatga aaataattca gattttaaat aataatgtag ccttagtaaa aagaggtaaa
      541 aatgaaatta ttgtatttgt taaaggaatt ggctttaaaa aaagagtggg acaagtaata
      601 aatgaaaatg aaatagagag aacatatata ctagattcat acgatatgct agaacacttt
      661 agttatctac tacaaaactc agactccaat aatatagttc ttattaatga aataattgaa
      721 tatggtgaga aaactttaaa tataaaggca agtgattatc taagcttaac cttactagac
      781 catttagagt ttttacttaa aagatgtaaa aagaatcaat ttataaaaag tcctttggta
      841 tggaatgtta aaagatttta tccaaagcat tttgaaattg gaatgcatgc actaaaatta
      901 attggtgata gtaagggaat taatcttcct gatgatgagg cagtatcaat agcacttcat
      961 tttgtaaata tggaggtaaa taaagagtct catgatagta caattgtaga gttgagaact
     1021 ttagcagata tagtttctat aataaaatat cattttaatg tagagctaga tgaaacttca
     1081 acaaattata tgagatttac tactcatcta cagtacttta tccaaagaat tatgtcagag
     1141 gaagcttcaa tagatgaaga taattctata gatttatata aacaagtaag tcaactttat
     1201 ccaaagtcat ttggaagtgt tcaaaagata agaaaatata taaaatcaca atttaatgtc
     1261 gatatatcta taagtgaaga aacttattta atgttgcata taaatagggt gactcaaaga
     1321 ctggaggcaa aatcagatga aatataaaga tttaaatgaa aatataataa aacttatagg
     1381 gggaaaagaa aatataaagt cggtagcgca ttgtgttact cgtttaagat ttactttaaa
     1441 tgataggagt atcgctcaaa cagaagaaat taaaaaatta aaaggagtaa ttgatgtagt
     1501 ttctaatgat gttgcttatc aaattataat aggtactcat gttgtagatg tatataacga
     1561 gtttatgtct atgataggtt taagttcaag tgaatcaagt ataaaaagtg aaagaaaaaa
     1621 gggaattaga ggtatcaaag gtatatttaa ttccatcttt gtggtagtct cagagactat
     1681 gacttcagta attgaagtac tacttgcagc tggtatactt gcaagtatat tagcactttt
     1741 aaatatgtct ggcatacttc agagtgacag tcctacatat caaatattag atacattaag
     1801 aagtgctaca tttcacttct taccagtatt aattgcaata gcatcagcaa aaagacttaa
     1861 tgtaaatcca tatatagcag tagtattagc agttacgtta ttatcttcat caatagatgg
     1921 tgtagaagga ttaagtttat ttggtataaa tttacagtct acaacttatg caaacagttt
     1981 tattccaata cttttaggag tatgggcaat gggaattata attgaaggtt tgaaaaaaat
     2041 attacctaaa gcactacact attttttagt tccagtatta tctttaataa taactctatc
     2101 agttacatta actgtatttg gacctattgg tatgtggatt ggtgatggat taaactatgc
     2161 atgtatgttt ttaattgata cattgggtaa ttggagtgtt gttgcactgt atgcagcttt
     2221 acaaccactc ttaatagtct ttggtgcagc aaactttact atgcctatat ctttaaattc
     2281 tgtgacaaca ttggggtatg acccaatttt tatgggcgct gcaacaatat ctgatattgc
     2341 agtttgtggt gcaatgtttg gatatttctt aaaaactagg aataaagaac aaaaacaatt
     2401 atttggtaca gtaagtttta gtgcacttat gggagttaca gaaccttcag tgtttggtgt
     2461 gtttatgaaa tatagaagac catttgtagc agtaatgata ggtggaggta taggtggttt
     2521 aatagcaggt ttagctcaag ttaaaacata tggaatggtt tggggattag ctgcattacc
     2581 aacgtatctt gttggaggag aggtatctaa ctttacattt atgataataa gtgtagtagt
     2641 atcatttgta gcagcaacag cagcttccta tttactagga ataccttcag atgaaaaaga
     2701 agaagttaag ggtgataatg aaaaagaatt agaactaata atcaacgaga acaattcaag
     2761 aactattagt attggaaatg ttgcaaaagg tcaggtaatt gcacttgggg aagttaatga
     2821 caaagcattt tcctctggag cattaggtaa aggggttgga gttataccta gtgaatcaaa
     2881 atcaactgtt atatctcctg tagatggaac tataactata gtatttccaa ctaaacatgc
     2941 atatggtata gtgactgatg aaggattaga aatattaatt catattggga tagatactgt
     3001 aaacttagat ggaaaattct ttgaaagtct tgtaacacaa aatcaaaggg ttaaaaaagg
     3061 agatgcttta gcagtatttg aatctgataa aattatagag gaaggctttg attctactat
     3121 aataactgta gttacaaata ctagcgatta tttagatgta atctcatcaa atgatgaatc
     3181 agaagaatta ttaactgtaa tagtataaat tttaggaggg aaaattcatg aatattaaag
     3241 atacattttt ctggggagga agtattgcag cccatcaatg tgaaggttca tgggatagtg
     3301 acaacaaagg acctgcaatt atggattttg taactaaggg ctcttatgaa atgccaagag
     3361 taattactga taaaatagaa gaaaaattgg attatccatc tcataatgga atagattttt
     3421 ataatagata taaagaagat atagctttat ttaaagaaat gggatttagt gcattaagaa
     3481 tatctataga ttggtcaaga atttttccaa atggagatga tgaaaatcct aatgaattag
     3541 ggattaaata ctatgaaggt ctgatagata cattaataga aaataatata gaacctattg
     3601 taacactata tcattttgaa ttacctatga atttagtaca taaatatggt tcatggaata
     3661 acagaaaact tatagatttg tatttaaagt acagtgagac tgtaataaga agatttgatg
     3721 ataaggtaaa gtactgggtt acatttaatg agatgaacca tattgaccct caaacagagc
     3781 actcggatat ttttacttat atgatagcag gtattaagta tagtgaaata gaaaataagg
     3841 ttcaaacatt ggcaaatgta gggtataata tgactttggc gggtgtaaag gttgcaaagt
     3901 tggctagaga aatcaatccc aacaataaag ttggatgtgt atttggacta aatccaattt
     3961 atccatacaa ttgtaatcct agtaatgtgt taaatgcatt tttagataat gaccgtgatt
     4021 attatcaaat tgatgcaatg tgcaatggga agtttccaca atataaatta aaagaatatg
     4081 aaaaaaataa tataactatt gaagtgactg atgaagacaa aaaagcattt aaagaaggta
     4141 agttagattt tataggactt aattattatt tttcaagtgt atctactcca aaagaaaatt
     4201 tatcaggtga taaatcttta tttggtggga ttcaaaatcc atatttggaa caaagtaagt
     4261 gggggtgggc aatagaccct ataggtttaa gatttacctt gaactatatt tacagaaagt
     4321 atcaattacc tatcttaatt acagaaaatg gtttaggggc atatgataaa atcgaagaag
     4381 atggaactat aaatgatgat tatagaattg aatatttagg taagcatcta tctcaaatga
     4441 agtctgcaat tgaagaagat aatgttgaat gttttggata tttgatgtgg ggaccaattg
     4501 atttagtcag tgcaactaca ggtcagatga gtaagagata tggatttatc tatgttgact
     4561 tagatgatga aggcaaagga agttttaaga gatataagaa aaaatcattt gattggtaca
     4621 aagaagtaat aaaatctaat ggagaagttt tagatttttc tacggatata gtagtagggt
     4681 aggaataaga taaatagaag ttaggaacta atgttaatta gtgtctagta aagcatttaa
     4741 aatagagtat agggtcttta aagtaaagtg tgtattcttc ttaaaagtaa tggcaactaa
     4801 aattactata aaaaggagaa tacacatttt ttatgtttat acttaagtaa atatttagac
     4861 atattcatag tataatttac tcattatata aaaatagtat gatttactca ctatataact
     4921 ttataaattt tctggaaaaa tgtcagaata tattgacaaa gaaaagattt aaaattataa
     4981 tctatattaa gaatagtttg acaatataaa aacaagtatt tttataaata gtgaaattat
     5041 ttttattgtc aatttaagaa taatttagga ctactataaa gataaaggta tagatgtcat
     5101 tatatgataa attatacttg tatagaaaga attttaaagt atggcttatc attgatttaa
     5161 tataataaat aatttttgtt tctagtaata gttcctagga ataagatatc taaattcgtt
     5221 tagaaatagt ctaatttaca aaggagggga tgcactaata gataaaattt ctatataaag
     5281 aagacttaaa gtgaagtata ttctgataat attggtttaa tgggtatatt attatttcgt
     5341 tttagatatt ttaagaataa tttaagacgt ttataaaaat gtattctata tctaatattt
     5401 aaataaatat aagtcttcca acatgtatac taatatagag agtagttgaa gtacaattct
     5461 aactcgtaaa attatgtaga aagtaaaaat caaaaagaaa tctagtaagt tgataactat
     5521 agttaatatt tagagagtta actctagtta tatttattta gatattttag gaataattta
     5581 ggacgtatat aatatcatca aaaaatatca agctatacca tatgtagtta agaataactg
     5641 cataatatac attttataat tattgtttta ttgataaaaa attattatat ttaggaggaa
     5701 acaacaatgg aaaatttttg gaatccactt acttgcttta ctgtatgtgt aatgatttat
     5761 gcttttagtg agtttttatc taagaaaaca aaaggtgcaa tttcaacatt gttatttgta
     5821 tgtattatat ttttactagg attttggaca aatattttac caaaagacat tacaggagca
     5881 tcagggatat tagctgcaat gagcaacttt ggtatagctt tattaataac taacttagga
     5941 acacttataa atcttgaaga cttatgtcat gaatggaaaa cggttgtaat tgcattagta
     6001 ggtattgtag gaataggagt tggctgttta acagtgggta gtatgttatt tggcagagag
     6061 tatgctttaa tagcagcacc tccaatagca ggttctactg ttgctgggat tatcgtaaca
     6121 actgttgcag aagctgcaaa tagacctgaa cttgctgcat ttgtaattct agtattatca
     6181 tttcaaaagt tctttggtat tccgataact acatattgta taaataaaga attaaaattt
     6241 aaaagagata acggggattt tttgaaagat gagtcaaaaa gtaattttaa acttccaagt
     6301 atgagaattt ttaaagaaga tttaggtaaa aaatcatcta ctctagtgta tcttgcaaag
     6361 ctttcatttg ttgctatgat tggtaatttt gtaggattgg ctactttaat accaggattt
     6421 acccctgcaa actattattt aaatcctaat atagcatgtt tgttagtagg gttgattttt
     6481 acacgaatag gttttttaga aaaaggaatt ttagataaat ctcaatctaa tggaattata
     6541 atgtttggtt gtatgttgat gttacctgga ggacttgcta aggtaactcc aacagcattg
     6601 tttgggatga ttgttccaac tataggaata cttgttgtag gttctgtatt tataatatta
     6661 tttactgcaa ttgtaggaaa actattggga tattctccaa gaatgtcagc tgcaattggt
     6721 gtaacttgta tgctagctta tcctgcaaca cagataattt ccaacgaagg tattgatgct
     6781 atggaaggaa ctgaagaaga aaaacaaagg gcaacagatt atttattacc aaagatgatt
     6841 ataggaggat ttgttactgt aaccattgca tcagtggcat ttgctagtat aataggtcca
     6901 attatatttg gttgatagta aatatactta taggaggaat aggaaatgat aggaagtata
     6961 tctataaatg agatagataa aaaaagattc aaacttgatg atttaagtaa gaaaatatgg
     7021 gaaaatccag aaaaagcatt taaagaattt aaagcatgtg aaaatacagc aaactttcta
     7081 agaagtgaag gatttgatgt ggaagtaggt gtaggaggtt tagccacggc tattagagct
     7141 agttttggtt caggtaaacc agttataggt tttatgggag aatttgatgc attacctggt
     7201 ttaaatcaaa aagtttcaac aaagcaagaa gcatttgaat tgggtgcata tggtcatgga
     7261 tgtgggcata atttattatg tacagcacat gtaggggcag tagtagggct taaaagagag
     7321 atgatagaaa ataacttaag tgggactata gtattttatg catgtccagg agaagaacaa
     7381 ttaacaggta aaggatttat ggctagaggt ggagcgtttg aagggttaga cttagctata
     7441 aattttcatc caaataaaat tagtgaagct acaattggta cttcaacagc tgttaactct
     7501 gtaaagtttc actttaaggg aaagactgca catgcagggt cagaccctca aaatggaaga
     7561 agtgcactag atgctgtgga acttactaat gtgggagcta attatttgag agaacatgtt
     7621 acttctgatg taaggattca ttatacaatt acagatggag gagtagcacc caacatagtt
     7681 cctgataaag catcagtatg gtattataca agagctttaa gtagagaagc tgtagaaagt
     7741 acatatgaaa gacttgtaaa ggtagcaaaa ggagctgcaa tgatgactga aactgaagtt
     7801 gaagtagagt ttttaggagg gtgttataat actttaaaca atcatgtttt agcaaatctt
     7861 gtatcagaat gtatgaatga gattaaacaa gagccttgga ctcgagagga attggatttt
     7921 gcagctgaat tagatagaca aagcccacaa caatataagg ctatgataag taaatataat
     7981 ttgccagaag gaactcatct atattatggt ggaggaaatg ttacaaactt taatagttat
     8041 ggctctactg atattggaga tgtaatgcat atagttccga cagcatactt ttttacaggg
     8101 tgtacgaatc taggagcacc aggtcatagc tggcagttta catcttgtgc aggaagttct
     8161 ataggagaaa aaggtatgat atatgcatca aagattatgg ctatgtttgg agctaaaata
     8221 ttaaataatc cagagatagc taaaaaggca aaagaagaat ttgataaatc tatgaatggt
     8281 aaaacatata aatgtcctat tccagatgat attccaactc cttaaaaaga catgaaattt
     8341 aatatataaa attataattt ttatatcagc atcatttcat tactaaaaga aagtgagatt
     8401 ttgctgacta tctgattagg aggaaggaat atgaaaaatt tttttaaaga agcgcagtca
     8461 atagaagggg aaattattag atggagaagg tatttacatg aaaatcccga aattggttgc
     8521 aatctaccga aaacagtaac ctttgttacc agtactttag aaaaaatggg atattctccg
     8581 aaattgacgt ctaataatgg aatagtagct gttttagaca gtgaaaatgg tggaaagacc
     8641 ttattattaa gggcagatat ggatgcactt cctattaggg aggagacgga tttacctttt
     8701 aaaagtaaga ataaagatgc atctcatagt tgtggacacg ataatcacac agcaatgctc
     8761 ttaggagcag ctaaaatact tatggataat aagcacttac ttaaaggtag agtaaagttt
     8821 gtatttgaac cagatgaaga gactaccaga ggtgcaaaat caatgattga tgatggtata
     8881 ttagaaaatc ctcaggtcga tgcagctatg gcatttcaca gtatggtggg taaatttctt
     8941 aacacaggtc aagtagctta ttcacgtggt ccagctatgg catctgcgga tatatttgaa
     9001 ataacagtag aaggaaaagc aactcatgga gcaagccctg aatttggagt ggacccaata
     9061 aacataatgt cgcatataca aatagcatta aacactatac tttcaagaga aaaacctcag
     9121 aaagagcctg tagttttaac tattggtatg tttaatgcag gaaacgtacc aaatgctata
     9181 ccaaataaag catctatgtc aggaacttta agaacatttg accaatttgt tagagaaaaa
     9241 ttaaaaaata gaattattga aatatctaca ggaatagcta aatcatttgg aggaaatgct
     9301 aaagtggagt ttaaaatggg gactcctgca gttataaatg atttggatgt aggagatgag
     9361 attgtatctt atgttaaaga agttatagga aatgaaaatg taatagactt tccatctgca
     9421 atgggttcag aagatttttc agaggtttta ctaagggttc caggagtatt tttatggatt
     9481 ggaatgggaa gtattagtca gggatataat tttggtatgc ataatcctaa agcaattttt
     9541 aatgaagagg gattagttta tggttcagct ttatttgctc attgtgcagt aaaatggtta
     9601 gaaaataatt ttagtagata ataacataaa atattattaa atatcataaa aggtatatct
     9661 taaaaagatg caaagatata ccttttagaa agtcatatat aattttactt aatattagat
     9721 gataaaatat ttttatgcat tttggatttt aatatttatt ttctgatata aataatttgt
     9781 ataccctttc aggtctgcct tttgttgagt tttgtttttc atataatata gtagcgtttc
     9841 cagactttaa gagactactt agaaatctat tagcagttct aactgttaca tttaaacatg
     9901 aagataattc cttaggagta acttcatctc tttgtagaat ttcagtaaca gatataatct
     9961 tttgaatagt aagagtagac aatttagaac ttttggcaat tgtatttata tgtggagtta
    10021 ctttatttga aacagtaagt aacttatcac acagtaaagg tcctattgtc tcataatttt
    10081 cgttaactaa gaaactgtaa tttaaaggat ttattttaga ttccttatta gcacttatgg
    10141 cactagacat agcttgcttt atatcattac caattccata tccaatacat actttaatat
    10201 ttgtactatt ttcaatagat tcttttatat aacatgcagt aaaattttta gttaatgatt
    10261 taatcgtttc acatttagtg aaaattttaa aagaattact atttttttca attataaaat
    10321 cggttaattt atctttttta atactattta atattttata aacttggtct agagtagagt
    10381 catcataatt tgtatcttta actgttatat atattacact tggttgattt cccttcattc
    10441 tatgtaaatg aatatctttt attaagttat taaaagtatt ttttaataaa tctatatcag
    10501 ggtatatgaa atgaaagttt actcctgcat tttgtaacat aggaacaata ctactaaaac
    10561 gagtagtaga aaaatcgatt ttcccttcat tccatagatt aatatgtttt tttgcaatct
    10621 ttttttcaag ttttgctatg tcagataaac tcattttaga tgcattttca tcaatactat
    10681 ccattaagtc tccaaatgtg ccatttgata aataatatga tatatctttt ggattatctg
    10741 cccagtctgt taagtcaaag tatgctctgg aaaaatctaa tgtattatat ttaaagataa
    10801 gctttagaaa catatcatag taactttgta agtcagtacc aaaatcaact agaggttttt
    10861 taatagttcc agcctttttt gtaatagctt ttttggggat ggggccacta actgcaaatc
    10921 catcaaacct atcttctatt tctaaatata aatctccaac atgagaaaaa tctctataga
    10981 tatatatttc aatttctgca ttaatattta acttttttat agaattatct acaaactctt
    11041 ttaaaaattc ggttgttatg actgctattt tcatcataga ttacttcctt ttcaattatt
    11101 ataattattt tatattaaat attacattaa tctattgttc tagttaaaat cgtatttcaa
    11161 ttaaattcaa ttaaaataaa taactcttta taaaaagcaa ttatttaggt agaggaatat
    11221 ttgctaactt taatagtctt tgttaacttt aattttattt aagttattat agtcttacta
    11281 attttataat tgtagattta actactttat gttcttttat tgtttatgta gttgatttag
    11341 aagttatttt aaccatttat tttaattgaa gttgtttgac ttttaaatcc tttgtgtaat
    11401 ctttgttttt ctagccatga taaaagtatt tctatttgta tcactatata taataatatc
    11461 atgacaaaat atttattgtc taactaatta taatctatcc aaaatgaaaa tgggtgtgag
    11521 atattattac aacaaattgt attagtatta aaaagattaa aaaattaaaa aactaaacag
    11581 ttaaataatt aaacgattaa gtgactgtca tataacaatt tataatttta tttaacagcc
    11641 acttaggtat ttaagagcga tagaattgag tgtatatcaa attataataa tttcctagta
    11701 aataattgaa aaataaggta gtccattttt atatttgata tctggtttac cttgaataag
    11761 tggatataga taatttaggg cttcatcagt tatataatta cattcttcat ttatccactc
    11821 tttaggaaaa tattttgtct tgttagctat tttagaaata tcagtatgac taacttcata
    11881 cttataagga ttattgcatg ttctattaat gatagccata actcctgtat atcctttttt
    11941 agatagttct atcccatatg caccaacttc agctgcttgt tttaaatcag tatctgaagc
    12001 taaatgcata gcacatcttt gtattacacc aagttctaag gtttttactc ttgttgtaat
    12061 tgatgatgat actataagat tctttagata gttgcttact ccacctaatt gggaatgacc
    12121 aaatttatca tgagcagaag ttttttgttc gcatataaag ttgccgtatt tatcccttat
    12181 accttctgat gcaactatat aagccttatt tttttcttta aatatttttc taacatcttc
    12241 tataaactta tcttcataga aatcaatttc tggaaggtat attaaatcaa caagtggagt
    12301 atcattaagt ctagctagtg aagaagaagc tgctaaccat ccagtatctc tacccatagt
    12361 ttctactata aatataccat tatttttgta tatagaaaaa tctaagtatg tttccattat
    12421 tagtgtagaa ataagctttg cagcagaacc aaatccagga cagttgtcag ttcctaataa
    12481 atcattatct attgttttag gaatacctat aaattttatt ttacaagtag tgtttttgca
    12541 gtattgagaa aatttcatca ctgtgtccat agaatcattt ccgcctatat aaaataatgt
    12601 atctatttta tattcatcta gtatatttat aactctatca taatcataag aatttatttt
    12661 ataatcagcc agtttgtatc tacaagaacc aagaccagac gaaggtgttt gctttaaatt
    12721 taatacatta tctttgttta aggagtctga atctattata tttttgttta atataccttc
    12781 aatcccattg ataccaaaat atactttatc aaagtattta gtttctaaat ttttttcata
    12841 aataccaact gcagaagcat tgataacagc tgtagggcct ccagattggg caataataca
    12901 gtttctcatt ttacatctcc ctttcattaa tattgttatg aatggtactt tttatcgagt
    12961 aaatttatat ttatagtctg attatatatt aaatgaacta gctatatcaa ttgagttagt
    13021 atagacaata aatgccataa gaatgtggta aaaaactaac tttttatata caattaatgt
    13081 ctataattta ccacaatata aaggtacttt taaggagtag tcaaagtgtt gtgaaaaaaa
    13141 atatatcagt gtaatattaa tttacaaagc aaaataagtt cacagttaac aaaagcagaa
    13201 taagttcata aaagaaatat atacagcaat aaaagtaatg ctaaataaaa gtaatactgg
    13261 attaaaaaat attaaaaaaa tattaaaaac taatatttaa tactaattaa agtaaaatat
    13321 ggaggtatac aaatatgaaa cacataaaaa tagcagcagg attagcacat gtaaattacg
    13381 gtcatatatc agccgtagtt aaagaagcaa tggatgcagg tgtagactac gtacattcag
    13441 atgcagcaga tatgcatgac ttaaaaaata tgcaacttat gggtggtcat caaataatag
    13501 aagcaataag accggtgaca gataaaccaa tagaatgcca tatatacaca agagattgtg
    13561 atagattatt tatagaaaaa atagcagcag caggatgtaa cttgttgata ataccagcag
    13621 aacatttttt aggtgctcct cttgcataca taataaatta ctgtagagaa tttggtatga
    13681 aagtaggatt aacaattgga tgttacacac cactatgttt tgttgatgaa gctatatatg
    13741 atatagatag attgcaaata gtcgttcatg gtgttgatga aactgatgga aaagataact
    13801 ggggatggag aaagagtgct gttgatttag taaaaagagc tagaaaaatg atagacgaaa
    13861 agaatcctaa gtgtgaatta gcaatagatg gtggactaag agcagacaat atggagccat
    13921 taatagaatg taatccagac gttgtaatat tatcttcagc aatattcaag gataaagatg
    13981 gtataacagc aggtgttaag aattgtagaa aagctataga tgaagcagct acaaagtttg
    14041 gtttagaata agataataaa ctatgataaa agagatgctt tcttaatgtt ttaaggaagc
    14101 attaatttta tgaaaaacta caggaagcta gactaattta attgattttt tatactgaaa
    14161 caatataatc ataggaggtt attaaatgaa aaaagaaatg ataaaagatt atttactgat
    14221 aacaatatca gcatttttaa tggcattagc agttaatttt ttctttgcag aacatacatt
    14281 agctccagga gggataacag gattatcagt cgtacttagc acattcttat caatgcctgt
    14341 tgagaatata tcattaggaa tatctatgcc acttttagta atgggattat tatttttagg
    14401 gaaaggtttt ggaataaaaa cattatatat aactcttatg ggcccattat tcttaaaagt
    14461 aataccacaa actcacataa ctgacaatct attagtagca ggagtgatag gtgggttatt
    14521 ggtaggaact gctataggga tagcaataat aaggggctgt agtactggtg gaactgattt
    14581 agttgcaatg cttattaata aggtaattaa gtttctgaag ttgccagtta tattatttat
    14641 gctagatgga tttataatag tagcgtctgg aataataagt aagaatttta tgatatctat
    14701 atattcattg atatctttat tactcataat aaaaacaata ggatttgtaa ctacaaagtt
    14761 tggtaagaat actgaagaaa ttaataatat aaataatgct tgtgctcaat aaaaataata
    14821 aaatttactt taaatataaa agtttaaaaa atataaaagc ttaaataaaa agattaaata
    14881 taaaaaatga aggtgtctca aaatgaattt tttagttcat gaggcacttt ttctatgaaa
    14941 tcaaatatat ttttatcatt tggacaatga aaaataggtt tatctctatg ttgagacaag
    15001 cctatttttg tttatttata agataatatt ttattttttt cagaatatag tttttttata
    15061 attgtactaa gtctagaaat atcattctta cttaaaagag catttatatt tatcagttca
    15121 gcattatgtt caaagtctac aggagcagtg gttagtatta agtccacatc atcaaagttc
    15181 gtaaatgaaa tagaagatag aggtatagat ttaactatat taatctgatt aaattcaaaa
    15241 cttaactttt ggactaataa attagataca ccatcactac agtgacatat taaaatagta
    15301 tttaggggag atttgcttct atctattgct gatattaaat ataaagcaag atatcctatt
    15361 tcgtcatcat tgacttcata attcatcaac tgtttgataa cagtattaga ctctttagca
    15421 gccttataag tgtaaggaaa tgttctcttt atatcattta atatgggatt tgtaatagta
    15481 aacccatagt ttattctgtg tagaactgat ttaaggtgat tagcaagaga ctttattaat
    15541 attaaatcat cctttaagtt taaatttagt atacttcccc aatgaacagc tattgcttca
    15601 gatagattat actctgtaat ttcttcattt ttaagaggtt caagagtagt agttttcttt
    15661 attgatttaa gtaatccttc tatatgaaga aggatataac agacctcttc atcaataaat
    15721 tctacgtcaa aagcttcact taggttagca cataaaattt ttgatttttc aaagtattca
    15781 tgttctaata attctctaaa aaaaccttca gataagttaa tatatctttt aattgaaatt
    15841 cttttaatac atatagctat atgtattaag aagtttatat aatactcatc actaaggtta
    15901 cttttttcta cttgtaaggt gtgtagagtg atttgagata atttctcaaa atcatagtta
    15961 aatagctcct taaatatttt tgttgatggg gtatctttgc attcattaga tttcgagaat
    16021 aatatttctt taagttcagt ataactttta ttaaccgtag caagttcaaa aattgctttt
    16081 cgaatatctt tctcttttcc ctctaaatat actccattat tggtttttct aactagagtc
    16141 actttaaagt tttgcaaaaa attttgaata actaccaagt ctttatgcac agtagctcta
    16201 ctaacatgta gttcattgca aatatcacga atcctaaact tagaattttt aataaataat
    16261 ttacttagaa tatacctttt tctatcttca ggagagtatg catatataca atttgattta
    16321 tcattgatat ctctaataac tttaagtttt atatcttcat tacctagaat aataacccct
    16381 gaaccagttt ttttatctag ggataaatta aactctaaaa gccattcatc taaaataaca
    16441 aggtcattac gaatagtttt attactaact tttaattctt cggcaatagt atctacagta
    16501 atatagtctg agctgttgag taataattca gcaatatcta ataatctttt gttcaatgca
    16561 aaccctccta aatcttagtt actatttatt aaccttggac caatctcttt caaaagtatt
    16621 ggcaccatct attgtaagct ggttaaaaga agctttttta aataaatcat atgttacagc
    16681 tgcataatca catccacaaa gagatgcttg agttaagtgg aatacatttt taatagaagc
    16741 tgcaacaact ttagtattat atccatttat tgatataagg ttacatattt ctgtaaggtt
    16801 ttttatacca tcattcccat tttcatcatt tctacctata aaagggaata ggtaatcagc
    16861 acctgcattt atagctaatg atgcttgatt tacattgaaa atcaaggtac atgcagtttt
    16921 tacaccttta ctatttaata tgtttataag ttctaagcca acttcagaga aatttatttt
    16981 tattatagtg tttttattta tatttaatat cttatcacat gaattaatta attcgtataa
    17041 attatttcca atgacttcag cagttaatat ttctggattt aaattagcac atgtctcaat
    17101 aaattcatgg aagtttactt tctctttaag atacatagat ggattagcgg ttattccctt
    17161 aaatccatac tttagacact tttgaatttc atcaagatta gcactgtcta tcaaatattt
    17221 cataatttaa ttctccttta agctatttgt cataaaaaag tgtatatact ctatttttat
    17281 tattaagtca attatacaat aagattgatt ataaaattat aacatgggta cttaataaaa
    17341 tttacataat gatatggtaa taataaaaca ttgattgtct aataattacc ataagcttta
    17401 gtaaataaga gttaacagtg aaggtattgc cttaaaaatc ctatgatatg tataatttga
    17461 atatgaaggc aataatttaa gggaggaaaa atatgattaa cttttatcaa ccatcaagaa
    17521 taaattttgg acaaggaact ttaagtgaat tacctagaat aataggaaaa tatggaaaga
    17581 aatgtttgtt agttactact ccaaatgtag agccattaga caagttatat aaaagagtta
    17641 cattgaattt aatagaaaaa ggtatagaag ttgtacactt tgattaaaaa atagctacgc
    17701 acactcgtga ctttagtcat gagttaatag ctaaaatagt cagcatatag ggaaacctat
    17761 atgtagagat aggatagaac ctatccaata ctacttgaat tgctggaaac ccctaaagct
    17821 aaccaaacta aaacataagg atgaaataaa cctaagtgtg aaagttacga aagtagaaaa
    17881 aattggttag atggtataag gttaaatcct aagtacttta aaatgggcaa tcagcaggta
    17941 agctccgaat aggagaaact tcaacgacta ttcctcttga gggaagtaca ctacaagtta
    18001 tcggtagtgg aagtgggtag accttaacgg ataatgccga aggataagat ata
//
LOCUS       DAEHWO010000088        18006 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEHWO010000088 DAEHWO010000000
VERSION     DAEHWO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18006
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.088"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(391..1066)
                     /locus_tag="KNP54_003271"
                     /pseudo
     CDS             complement(391..1066)
                     /locus_tag="KNP54_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(1614..3143)
                     /locus_tag="KNP54_003272"
     CDS             complement(1614..3143)
                     /locus_tag="KNP54_003272"
                     /inference="COORDINATES: protein motif:HMM:NF012862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HBF0894134.1"
                     /translation="MKSLKALIVGVSKYSIVKNKDLLFCKNDIIEINNVLHKRLGITS
                     NNIRTLGMEYEVRKDLFFKTFQEISDSIGDDDTFIFYFSGHGCICNNGVHYLVLSDEL
                     VSIQFVIDFIEGLNCKNKIVFIDCCFAGKFNVSDKQKINIKDIFSLFDRKGCAVLVSS
                     SEYQESFSLPDSSISRFTSLLSEALRNEYIVRKGELSLRAISKYINLRMSILNKNYIN
                     CKQNPIFRSNILGDIYFNVKDYKSYIKKKVFQEHDDYIIYNVKSLHISIIKRYSVEVI
                     LKNKFSYCDISEISKEVFDIVKSVEVYNSEIGEDRLKGKDANIIWVYFGKDEIDMING
                     IYMCKTTWIDKYQEKDIWYSVNGKNKFFINGVHTETYDNYESLKSYISQNTITKEKAV
                     YEVKEILTNMINISEEIISFYNEYENKKICEDNIFQIIDSRKKKMDECYNKVINLDFP
                     PIEIKDWFDKCINLVSTIQNFGVYWDHSRTEENRKQCMEMNIEDYYKDLREVIRLSEE
                     I"
     gene            complement(3842..5272)
                     /gene="dcm"
                     /locus_tag="KNP54_003273"
     CDS             complement(3842..5272)
                     /gene="dcm"
                     /locus_tag="KNP54_003273"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007157505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBF0894135.1"
                     /translation="MKKITIDKNRVRKIMKEKNIRSQNQLALNMGITKNQLSAILSEK
                     FTPIKSNVEKLCEVLDIGFDEIMCLEDVNEKQLKFTNICSSNKDYIEHRDCTYKELSE
                     YELNPRERNKNNKHIDISNVLAKRAYTCVELFAGAGGLALGLEKAGFKEVGLVEWDKY
                     ACDTLKLNRPDWNVIQGDIVKIAENGIKNYIDNNIEIDLLSGGYPCQAFSYAGKKLGL
                     EDVRGTLFYSYAKILEELKPKVFLAENVRGLVSHDGGKTLKTMIDVFSEIGYNVKYEI
                     LKAVNYGVAQKRERVIIIGTRKDLSHVDFKFPKSFEYVATLRDALKNVPKSEGARYPE
                     RKKKVLDMVPPGGCWIDLPDEVARDYMGKSYYSGGGKRGMARRISWDEPCLTLTCSPA
                     QKQTERCHPDETRPFTTREYARIQSFPDEWEFTGSVSQVYKQIGNAVPVKLGKAIGLS
                     IVDYLNKIEKIYVTEEVAITEEEYVI"
     gene            5485..6201
                     /locus_tag="KNP54_003274"
     CDS             5485..6201
                     /locus_tag="KNP54_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002601887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HBF0894136.1"
                     /translation="MTELEKQEILDKAKDFFTNILVANHKKNTIKLNLKAFNINPFLV
                     KYLASFLTGSNKPEDIAKALIYPRVLGTSINTSFGTNLQKFCITTLDGFASTTSGIDI
                     EFIDCIDGRRKFCQIKAGPNTINKDDVKTIIDHFSSVKRLARTNGLSLSYNDLIVGVF
                     YGTENELNAHYKRINEEYPVVVGQDFWYRLTGDENFYFDLIDTIAQSALEEDCTVLLK
                     KTISNLADEISKDKSLFNQK"
     gene            complement(6446..6724)
                     /locus_tag="KNP54_003275"
     CDS             complement(6446..6724)
                     /locus_tag="KNP54_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894137.1"
                     /translation="MYDEIIEIYFDYWINEHMYRKVLEKDEYYNDRCKEIKKVNKLLE
                     KNLSEEKKMDVLIELNDLFNSVIEIERELGYKLGFKAGARFMIELLNS"
     gene            complement(6972..8306)
                     /locus_tag="KNP54_003276"
     CDS             complement(6972..8306)
                     /locus_tag="KNP54_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0894138.1"
                     /translation="MDNMSNLVKNTEAEQSILGSILLDSRKIEEIEILISEDMFYHQE
                     HKHIFNSVKDIHKRDEPIDIITLTEDLKKKGLIDYVGGISYLTKLSTIVPTIGNVSHY
                     IEIVIEKYKNRNIIDKFNKFKLGEIDDNTLIYQLEKYVNEVNQKLVKKDSSITAISER
                     AFEYINDEIEEGIDIGIKFLDETIGGLYSGELITIAAKSGRGKTALALQIMRNVVFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNEEEIIKYINALSTLNQENNLY
                     INDSVNTISGIKREIKSIKPDVVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPIIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALDYCKTMGIE
                     DIKELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGSLFSFKECKKVKEV"
     gene            complement(8319..9062)
                     /locus_tag="KNP54_003277"
     CDS             complement(8319..9062)
                     /locus_tag="KNP54_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894139.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNKSTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNVNNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKANFDWIMSPNNFIK
                     ILEGNYQDKSINVKVDAEAYSPDDSQLKW"
     gene            complement(9083..9397)
                     /locus_tag="KNP54_003278"
     CDS             complement(9083..9397)
                     /locus_tag="KNP54_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894140.1"
                     /translation="MADTNNLEVLKTLQATLNILVKQEQEAQEKEKGYKEIQTYRRDK
                     AQLITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDNWFIENANGI
                     KL"
     gene            complement(9401..9595)
                     /locus_tag="KNP54_003279"
     CDS             complement(9401..9595)
                     /locus_tag="KNP54_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003450825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894141.1"
                     /translation="MKLKLKRIEKGIKQYELAEKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKEE"
     gene            9879..10595
                     /locus_tag="KNP54_003280"
     CDS             9879..10595
                     /locus_tag="KNP54_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0894142.1"
                     /translation="MIKKISTALSIPINRLIIDESDLDTSTNNYTNLKELDLVVKTFD
                     NYSAKLIGNNISKFRNINNISLKELSEKINCSENEIINYENGTKMPRIEILKKIALAT
                     YTKIEDLFGFPLEEIKIDNQTILYRNPQTGYIIDNFLIDFINKDINIDNTPVSYYIDK
                     SEFDLVIHILKNYGYDVKTDYKTKFEIADNADTIKPISLSFSDFKDFSKNLNWVINGL
                     VENFIQENSNGLIEDEDEEY"
     gene            10692..11444
                     /locus_tag="KNP54_003281"
     CDS             10692..11444
                     /locus_tag="KNP54_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBF0894143.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVSDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDEYNYKSYKELFKNGN"
     gene            11434..12600
                     /locus_tag="KNP54_003282"
     CDS             11434..12600
                     /locus_tag="KNP54_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBF0894144.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNSDILKAGELYRNDNYVFCNELGAPIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKIEAVEKLDKIFSL"
     gene            complement(12717..12947)
                     /locus_tag="KNP54_003283"
     CDS             complement(12717..12947)
                     /locus_tag="KNP54_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894145.1"
                     /translation="MEANKTLLQSLYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGISDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(13196..17767)
                     /locus_tag="KNP54_003284"
     CDS             complement(13196..17767)
                     /locus_tag="KNP54_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007062489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBF0894146.1"
                     /translation="MTFEEIMEFNKPYNQKNFDELVNAIKDGYVVPYIGAGMSMLFKD
                     IYPSWSTFLNNTSEEYLEDEDKILFEKIEDYEKKAEFLYEELAKVRFSKHLKKVFGAG
                     YLDAKDKDDFIDKCVYLIPIIFGSGLIITTNYDKVLEKNYGLHNKTVLVSHPGHFEAL
                     NNALRNNELVLYKIHGDITEPTTSIVLTKEQYEKAYSNDELRKMLTQVYTSKELLFLG
                     CSLEKDRPLELLQQVSEAGTGHYAIIPVSSEKKKHRRIELENEYYIQTIMYPEGKHEC
                     VRIILERILEIVLPDEYRRLKDRSLKESRLTNLSCRLTEKWFQNQNNIQIKNLGDRYL
                     PELNVELSLENTFNALGKNEEFKQRFDEKTDKVLSSIKKQKINEVEVDVLVIEEIIQQ
                     FYDKANERLDIKLLKKHFEKISAALDDRINNFKNIIINEDCEKSKKREDEIYKLKQTQ
                     KDIYVYIKYLDSKEIKVVNSPYILLHSAGGMGKSHIIAHTIEKRNMDGHKSILFLGQH
                     FKLDKTPIKHMLEILEIECEFEELLEILNEIGEKEQQRVILFIDALNEGQGKELWKYY
                     LNGIVEQIKKYPWIGLILSIRSEYIPSLIDNNNKIKENLVFIEHQGFSSIEHKAMKKY
                     FDYYGIPYSNIPMPNQEFRNPLFLRIMCETFKGEEINLDTISFTDIYKNYLNILNLRI
                     SESCNYSRHANVVTEVLNEMIKYKYGDGLGNNLIPANKSVEIIINIASKYKINNVIID
                     ELIANGIVNKTVNLNDEEYMHVTYEKLEDYLYANLLVKELKEIGVVDFSHKYKYLVEY
                     EDILEVLAIVLSEETGSDIPNEIFEVFKNKETNYNVISAFINALKWRKKSTITEKTLD
                     YINKIVLGKSYYKIDFYNVLILISTKVNHTLNADYIVKYILQNTMADRDAIFIPIFNE
                     VYEEEESSIKRLLGWCFDFEGFDNTSNETIRLSAMMIATFLISSNRDLRDKSTKALVN
                     LLTGKMDIVIDLLKTFEDVDDPYIIERLYAVAFGCVVSEQSEEMIEALAVYVYNKIFD
                     VDYVYPNILLRDYAKNIVDYAKYKIDSSVLKDMNVEPPYKSIFPKVPTDEEIEGYKYD
                     YKASDFKDYYWSQNTILNSMEVEYTRDGQPGWYGDFGRYMFQHYFHKWKGLDYNDLKN
                     IAIKKVFDMGYDVNKHGKFDRTVQNGRLRDSKYERIGKKYQWIALYELAAQAADNYKI
                     EVYTDAYGTKKEIYCKGTFEPDIRNIDPTVMTVINNNNNKRVHNQLFQFSPIPNNEWL
                     GDFSDLPSINDMVNSVYKNQDFLLLNGWYTWKEENDFKNKNYKNPEKDMWVLINSYII
                     KNDQLEPIVNALKGKDFMGRWLTEPNSNYTLYNKEYYWADGYYFFQNSYYCGEEWVQI
                     DEHKNILEKDYKVLLPTYSYTTEREGDIFQEDFSGTWHKPCSTLFYGLKLRYGQGDSI
                     LYNDYGEVVCFESSELLNEEIGFFINKEIFLKYLNEQGYSVFWTMLAEKRVLEEPYMD
                     RKYIQPTISGVYTLNGENRLVGETIESEY"
BASE COUNT         6070 a         2846 c         1823 g         7267 t
ORIGIN      
        1 agagcttcct ctgatgatat tacattactt gtaactacaa aaaataaatt tatagatata
       61 acatctttta ttaaagggtg atatacgtca aataagaaaa atgaaactat atatttaaca
      121 attcctatct tataaaaata attatagtaa gttcccaagt aataaatatc aaataataga
      181 ttatatcata tagatttttc ttcatattat aatcatgggt cttatcaaca ttaaataata
      241 taatgatctt agttataaga taagctaata atacagtaaa aaaagatatt ttcttagtct
      301 tatctgtatc tttatcgtaa gttaatatac tttttagtat cattattggt gtaaacaatg
      361 ataatattaa taatatttta tttatatggt ttaacatatt ctatcaccaa taaattttag
      421 aaacccctct tttatatctt tatatctata tctactaata ggtacttctt cttgactgtc
      481 taatattgca gtatttgact ttatattttc tacatagttt aagttagtta tataactttt
      541 atgacatctt acaagttcct ctatatttaa atctttttct attttttcta ggatacatat
      601 agcatcaaga gttttatttt ttgtatgtat tagcatgttc tttttttgaa cttctatata
      661 tttttttgct agattagatt ttgtatgtgt tagatttatt tttatttttt tcaatttttt
      721 tggtacatgt taatatgtgt ttttctagtt cttgaaaatt tattggcttt aataagtatc
      781 aataagctct tacttcatat ctttcctgta cataatttat tagagatgtt ataaatatta
      841 ttatctactt ttcttatgtt tcttgcgata tctatactat ttagttctgc catttttata
      901 tctaagagta gtgtatcctc tcaattaact ttgtaatgat tcttcttttg agctatattt
      961 ttttaattcg atattctttg tttttatttt ttaatatatt atcaacttga ttttttatta
     1021 cgatttgtat ttctttttca tcatcacaag ctgttattgt aatgataacc tctcctaata
     1081 ttgtattttt atttagattc ttcactttag gttaaaactt tttaaatgta tttatcaata
     1141 atatttaaat taaaaatgta taaaaatacc tatatccaat tggatatagg tattcgtgga
     1201 tttcaatggt ggagacgagg ggagtctata agtggttatt tgattgtttt gttgtttttt
     1261 gcaagtgtag gtatatagct atttagttat gatgttaaac tgattttttc ggatattttt
     1321 tattgtttat ttttgtagtt ggggtattat tggggggggg tggatgatat aatcttttaa
     1381 ttttataaaa gttccattaa cagcatatta tacgttttta aatatttact agactttttc
     1441 aaaataaata tctaattatt taaatcaata ccaatataat ttataaatgg atttataatt
     1501 gtatcttcta tcatgtttag tgtaaacaac ttattttaat ttaaattcgt aaccaacaaa
     1561 gtaccaatct gacttataat tctatattag tacaactatg gaaaaattta attctatatc
     1621 tcctcactta atcttatgac ttctcttaaa tctttgtaat aatcctctat attcatttcc
     1681 atacattgct ttctattttc ctcagttcta ctatgatccc aataaactcc aaaattttgt
     1741 atagttgaca ctaagtttat acatttatca aaccaatctt taatttcaat tggtggaaaa
     1801 tctaaattta taactttatt gtaacactca tccatttttt tctttctact atctataatt
     1861 tgaaaaatat tatcttcaca tattttctta ttttcatatt cattatagaa ggatataatt
     1921 tcttcagata tgtttatcat atttgttaaa atttctttaa cttcgtatac tgccttttct
     1981 ttagtgattg tattttgact tatatatgat tttaagcttt cgtagttatc atatgtttca
     2041 gtgtgaacac cgttgataaa aaatttattt ttcccattta cactatacca tatatctttc
     2101 tcttgatatt tatcaatcca agtagtttta cacatatata ttccatttat catatcaatt
     2161 tcatctttgc caaaatatac ccatattata ttagcatctt ttccttttaa tctatcttct
     2221 cctatttcac tattataaac ttcaacagac ttaactatgt caaaaacctc cttagatatt
     2281 tctgatatat cacaatagga gaatttattt tttaatataa cttctactga atatcttttt
     2341 attatactta tatgtaaaga tttgacattg tatattatgt aatcgtcatg ctcttgaaaa
     2401 actttctttt ttatataaga tttataatct tttacattaa aatatatatc tcccagtatg
     2461 ttagacctaa agataggatt ttgtttacag tttatataat ttttgttcaa tatactcata
     2521 cgcaaattaa tatacttgct tattgctctt aaagataact ccccttttct tactatgtat
     2581 tcatttctta acgcttctga taataaactt gtaaatctac taattgaact atctggaaga
     2641 gaaaatgatt cttgatattc gctacttgat actaacactg cacatccttt tctatcaaac
     2701 aaggaaaata tgtctttaat atttattttt tgtttgtcac ttacattaaa tttacctgca
     2761 aagcaacaat caataaatac aattttattt ttacaattta atccttctat aaaatcaatt
     2821 acaaattgaa tagaaactaa ttcatcactt aatactaagt aatgcactcc gttattacat
     2881 atgcatccat gccctgaaaa gtaaaatata aatgtatcat catctcctat agaatcgctt
     2941 atttcttgaa aagttttaaa aaataaatct tttctgactt catactccat acctaaagtt
     3001 cttatattat tcgaagtaat ccccagtctt ttatgtaaca cattattaat ttcaattata
     3061 tcatttttac aaaatagtaa atctttattt ttaactatac tatatttact tactcctaca
     3121 attaatgctt ttaagctttt catattccat tcccccttta taatttttca atttaatata
     3181 cttaaaatga tgttttaatt gttttattga ttttataaaa gctagtatca cactactttt
     3241 ttgacttttt cattatttac ttttgtagtt ggattataat ttttcaaggt aagtatatat
     3301 atatttattt acatcgcacc catataattt atatctctga tttatctgac ctgaacttag
     3361 tgtaatttaa accaatgtaa aatcatctat ctcttcacca tatatttttt aaaattcccc
     3421 aaaatattga tgttaataga atttcatgtg ttttttgtat tctactatcc ataagaattt
     3481 taaagtgagt aaatatttcc aatcatttat atcttattta atatcatttt attccctcaa
     3541 gtatttattt aaattgttat gctttattta taaaattata catacatttc taaagttaga
     3601 catacatctt taaaaacctt taatttgtgc tacttttttt ctaaaaataa taaatatata
     3661 aaaattatat atacaaaaaa ttaagttatg actagtttat aaataagtac ataataaaat
     3721 taaagagagc aatttttttt gctctctttc aaaatttata ttaaattgta ataataaaaa
     3781 taaaaacgct agttatctaa ggctaatatt ttcaacgatt atataaatat ctacataaca
     3841 gttaaattac atactcttct tcagttattg caacttcctc agtgacatat attttttcta
     3901 ttttattaag ataatctact atacttaatc caatagcctt tcctagctta acaggaactg
     3961 catttcctat ctgcttgtac acctgactaa ctgaccctgt aaactcccac tcatcaggaa
     4021 aactttgaat tctagcatac tctctagttg tgaatggtct agtctcatct ggatgacacc
     4081 tttcagtttg cttttgtgca ggactacatg ttaaagttag gcatggttca tcccaactta
     4141 ttcgccttgc catacctctt tttccgccac cgctataata actttttccc atataatctc
     4201 ttgccacctc atctggcaaa tctatccaac acccacctgg tggtaccata tctaacactt
     4261 ttttcttcct ctcaggatat ctagctcctt ccgattttgg aacattttta agtgcatctc
     4321 ttaacgtagc aacatattca aacgacttag ggaacttaaa atccacatgt gacaaatctt
     4381 ttcttgttcc tattataata actctttccc tcttttgtgc aactccatag ttcacagcct
     4441 ttagtatctc atattttaca ttgtatccaa tctcgctaaa tacatctatc atagtcttta
     4501 atgtttttcc accatcatga gatacaagac ctctaacatt ctctgctaaa aacaccttag
     4561 gctttaactc ttctagaatt ttagcatatg aataaaacaa tgtccctctt acatcctcta
     4621 accctagctt cttacccgca tagctaaatg cttggcatgg ataaccacct gatagcaaat
     4681 ctatctctat attattatca atataattct ttattccatt ttccgctatt ttaacaatgt
     4741 caccctgtat aacattccag tctggtctat ttaattttaa tgtatcacaa gcatatttat
     4801 cccattctac taatccaacc tctttaaaac cagctttttc aaggcctaat gctaatcctc
     4861 ctgctcctgc aaataattca acacatgtat atgctctttt agctagtaca ttacttatat
     4921 ctatatgttt attattttta tttctctctc taggatttaa ttcatattca ctgagttctt
     4981 tatatgtaca gtctctatgc tctatataat ctttattact gctacaaata tttgtaaatt
     5041 tcagttgctt ttcatttaca tcttccaaac acataatttc atcgaatcca atatctaaca
     5101 cttcacataa tttttctaca ttacttttta taggtgtaaa tttttctgat aatattgcag
     5161 ataactgatt cttagttatg cccatattta atgccagttg attctgactt cttatatttt
     5221 tctctttcat aatttttctc actctatttt tatcaatagt tatttttttc atttagttca
     5281 cctcttaata aataatatac ccttaaatag ttaataaaat acattaacta tttaaggata
     5341 tattatcata attctaattt ttatgtaagt agttataaaa acttaaaata aaatatctgt
     5401 aaacaaccta atattacctc ataattttac acattatgga atatattgta taattacatt
     5461 aatacttttt agggggatta ttttatgact gaattagaaa aacaagaaat actagataaa
     5521 gccaaagatt tttttacaaa tattttggtt gctaatcata aaaagaatac tattaagtta
     5581 aatttaaagg catttaatat aaatcctttt ttagttaaat acttagctag tttcttaaca
     5641 ggatcaaata aacctgaaga tattgctaaa gcattgattt atccaagagt tctaggcact
     5701 tcgattaata cgtccttcgg aactaattta caaaaattct gtattaccac tttagatggt
     5761 tttgcctcta caacttctgg cattgatata gagtttattg attgtattga tggtagaagg
     5821 aaattctgtc aaattaaagc tggaccaaac actattaata aagacgatgt taaaactata
     5881 attgaccact ttagctcagt taaaagactt gctagaacaa atggactttc attatcttat
     5941 aatgacttaa ttgttggtgt tttttatgga acagaaaatg agcttaatgc tcactataaa
     6001 agaattaatg aagagtatcc agtagttgtt ggtcaagatt tttggtatag gcttactggt
     6061 gatgaaaatt tttattttga tttaatagat acaattgctc aatctgcttt agaagaggac
     6121 tgtactgttt tacttaaaaa aacaatatcc aatctagctg atgaaatttc taaagataaa
     6181 tctttattca atcaaaagta atataaaaat gattaaatag cataatttac atttttagat
     6241 atttaaaaat aatattcacc aaacaaaatt attaagtaaa atgaaatgta tcttataaaa
     6301 gctgagctat aagtaaatct ttgtaaaaac aaatttactt atagcttttt tatgttcaaa
     6361 aaacacaaat tatatactat ttaatatatt ataaactttt atttgttaat actctctact
     6421 aaatttctaa catctcttat ataaattaac tatttaataa ttcaatcata aatctagctc
     6481 ctgccttaaa accaagctta taaccaagct ctctttcaat ctctataact gaattaaata
     6541 aatcatttaa ctctatcaat acatccattt tcttttcttc tgataaattt ttttctagta
     6601 atttattaac tttcttaatt tctttacatc tatcattata atactcatct ttttctagta
     6661 ctttcctata catgtgttca tttatccaat aatcaaaata tatttctata atttcatcat
     6721 acatgttagt acctccttga ctttcatctg gtacttaata tatacttaac ttgtgtagat
     6781 tagtgtacat taagtaccta atttataaag gtagttgtta tatttatatg gcaactacct
     6841 ttttctaata aatttttcaa tctaaatact atatatttta aatcttcatt gcttactatt
     6901 gaggattata tacttttctt ctaacactcc ttaaacaata gtttatatat cacttaataa
     6961 attatatttt ttcatacctc ctttaccttc ttacattcct taaaagaaaa caaacttcct
     7021 atataccaat aaggtctaaa gcctgattcc ccatctctat ttttagcaac tataatttca
     7081 cttaaattag ctccaaaacc tttttctcta cgtcttaatt cttttatatc ctctattccc
     7141 attgtcttac aataatcaag agcctctttc tctgtaggtc tatgaatata tatgactgaa
     7201 ttagaatcca tatatatctg ttttgaactt ctcattactc tatctccttt tggcctttca
     7261 tccttcaatt catcatttaa ttgagccaac tgtataattg gaatattaaa gtctaaagta
     7321 atctttttta tttgccttga taaatcagca aacttagctt ctccaacttc tttaccttcg
     7381 taatccaaaa tctgaagata atcaattata acaacatctg gtttaatact ttttatttct
     7441 ctcttaattc ctgatattgt attgactgaa tcattaatat agagattatt ttcctgattt
     7501 aaagtactta aagcatttat gtatttaatt atttcttctt catttagatt tctattcttc
     7561 atttttacaa ctgatattcc agttaaagaa gctatgtttc taaacaaaat ttgtatatca
     7621 ctcatttccc cacttataaa aagtactttt ttaccttgaa ataccacatt tctcattatc
     7681 tgtaaggcta gtgctgtttt tcctcttcca cttttggctg ctattgtaat taattcacca
     7741 ctatatagac ctccaatagt ttcatctaaa aattttattc ctatatcgat accttcttca
     7801 atttcatcat ttatgtattc aaaggctctt tctgatatag ctgttatact agaatccttc
     7861 ttaaccaatt tctgattaac ttcattaacg tatttttcta attgatatat aagtgtatta
     7921 tcatctattt cacctaattt gaatttatta aatttatcaa ttatatttct atttttatat
     7981 ttttcaataa ctatctcaat ataatgggat acattaccta tagttggaac tattgttgat
     8041 agttttgtca aataacttat acctccaaca taatctataa gccccttttt ctttaaatct
     8101 tctgtaagag ttattatatc tataggctca tcccttttat gtatatcttt cactgaattg
     8161 aatatatgtt tgtgctcttg atgataaaac atatcttcac ttattaatat ctcaatctct
     8221 tctattttcc tagaatctag taaaatacta cctaatatag attgttctgc ttctgtgttc
     8281 ttaactaaat tactcatatt atccataata taaactccct accactttaa ttgtgaatca
     8341 tctggactat atgcttctgc atctactttg acattaattg atttatcttg ataattgcct
     8401 tctaatatct taataaaatt atttgggctc attatccaat caaaatttgc cttccaacct
     8461 ttttcattgc ttccatttaa aaagctagtt ttactaacta tatgaataat ttctaataca
     8521 gtctctttat catattcttt tattctagca ttaattactt tttttctagc ttctgtaagt
     8581 ttctttactt ttgatagttc tgtacaagta atattgaatt tttctataat ttcactgtat
     8641 attttacttt tttcattatt tacattcttg ttagttgtta gttgcttgtt aattgcatgt
     8701 tgattagtct gttgattttc ttcattagat tgatatagct cccagttttc aatagttata
     8761 agcctatttt tgtttgttga tttatttgtt agaaatccat atctttcaaa tttctttaaa
     8821 gcagttctta cattctgaat acttacatct tttgaacaca tatttgctat actttccaaa
     8881 gatgttatta actgtcctga tttaacttca tattctttac ctccataaac ccatttatta
     8941 ggcttatgat taactgacag taataggttt atgagtatat ctctttgttt ggaattacaa
     9001 tctttatata gtgggctttc ttttatcttt ctatgaagct ttatccaacc tagattactc
     9061 aaatactatc acccacttaa gtctataatt ttataccatt tgcattttca ataaaccaat
     9121 tatctagttt attttttatt atatacactc tattatctat ccatatacaa ggaaatcctt
     9181 tatttttaga atgacataac tgtctaaatt ttgattcccc tatgggataa attttagaag
     9241 cttctttaca agtgataagt tgagctttat ctcttctata tgtctgtatc tccttgtacc
     9301 ctttttcctt ttcttgtgct tcttgttctt gcttgacaag tatattcaat gtagcttgta
     9361 gtgttttaag aacttctaga ttatttgtat ctgccataca tcattcctcc ttatcaaaaa
     9421 ataattcttc tacacttgta tctagttctt gagccaattt taacatcaac atattacttg
     9481 gattttttga tttacctctt tctaaagaag ataaataata tcttgagatg ccaacttttt
     9541 cagctaattc atattgcttt ataccttttt caattctttt taatttgagt ttcattgatt
     9601 tcctcctttc tttcataccc attttgtgta tcctcatttc tataaaatat tctaacaccc
     9661 atttggtgta ttgtcaatat atttaagtgt atcaatagac ccatttagtg ttataatgta
     9721 tttgaggtga aattatgata gataatacaa ttggaaaaaa gattaaacaa tatagaaaat
     9781 ctataaatat gtcaagggat gagttagcta ataagattgg ttgctcagtt tatgctgtag
     9841 ctaaatatga gcaaggccaa agaaagccta gtttagatat gataaaaaaa atatctactg
     9901 cattatcaat tcctataaat aggcttatta ttgatgaaag tgatttagat acttcaacaa
     9961 ataattatac taatttaaaa gaattggatt tagttgtaaa aacatttgat aattactcag
    10021 caaaactcat cggaaataat ataagcaaat ttagaaatat aaataatata tctctcaaag
    10081 aactctcaga aaaaataaat tgttctgaga atgaaattat aaattatgag aatggaacaa
    10141 aaatgcctag aattgaaata ttaaaaaaaa tagcacttgc tacttatact aagattgaag
    10201 acttatttgg atttccatta gaagagataa aaatagataa ccaaacaatc ctctatagaa
    10261 atccccagac tggatatatt atagataact ttcttatcga ttttataaat aaagatatta
    10321 acatagataa tactccagtt tcttattata tagataagtc agaatttgat ttagtaattc
    10381 atatattaaa aaattatggt tatgatgtaa aaacagatta taagacaaag tttgaaattg
    10441 cagataatgc agatacaata aaaccaatta gcttaagctt ctctgacttc aaagacttct
    10501 ccaaaaatct aaattgggtg ataaatggtc ttgttgaaaa ttttatacaa gaaaactcta
    10561 atggtcttat tgaagatgag gatgaagaat attagtattg cacattttca aaatatgagt
    10621 ttacctatta acttttatac attcatagtt aataaataaa aattagatat gatatgaaag
    10681 gagctaaaat catgaataaa tcatatatac caaaatacac acataaattc cctactaatc
    10741 tacctcatgg agataaaaaa tatactttaa catacattag aagaatgata agtgaatttg
    10801 tatatgatat gggtaaccta gaaaataacc cctttacatt cccagaagta caaacattac
    10861 ttgatggtat aaccgtaggt ggacataaat taagtgacca aaatcaaata ctaaatataa
    10921 aatcatcatg ggattatgta ataaaattaa gtaacaaaga aaacttatct ttaaataaag
    10981 atacaatttg ctctatacat aaaatagttg caaaagatga agctctaata gttggagatt
    11041 ttagaaatgg taacataggt atagctggta ctactcaata tgaatgcata gaagccactc
    11101 tattaaatga tttatttgta agcgacataa atatcataaa taaaataact aaccccttag
    11161 aaaaggctat aataataaat ttatggttgt cctattgcca attcttctat gatggcaaca
    11221 aaagaactgc tagacttacc tcaaacctaa tacttataag taatgatata ggagttctat
    11281 caataccagc taaacataaa caagaataca acacattaat gctaaacttt tatgaaacac
    11341 tagaagctga tgaagttata aaattcttat tagagaaatg tattacattc tttgatgaat
    11401 ataactataa atcatataag gagctgttta aaaatggcaa ctaaaagagc taatggagaa
    11461 ggctctatcg gaaaatataa agatggttgg cgttcccgta taatgattgg ctataatgaa
    11521 gatggtaaac caataagaaa agaattttat ggtaagactc aaaaggaagt taaagataaa
    11581 cttgatgctt ataaaaaaca atattattta agctctgata tttcagatga taaaataact
    11641 ttagagcatt ggttttacaa ttggttattt gaatatagaa taaaagattt aaaacctaaa
    11701 tcatttgaaa gatatgaaag catctatcgt aattatatta aagatactga tttaggcaat
    11761 gttaaattaa aggacttaag agtatctcac atacaaaaat attacaatag attgcttgat
    11821 tccaataaaa gtatacctac tataaggcaa ataaacacta aactgaaaac ctgcttatca
    11881 gaagctgaaa aacaaggtct tatacaacgt aattattgta ctatggtaaa tataccagtt
    11941 gagaaaaagg agaataagct tgaaatattg actcttgaac aacaaaagag ttttataaaa
    12001 gctatagatg gacataaatt agaggtatta tttttacttg ctcttggtac tggacttaga
    12061 ttaggagaat tattaggact taaatggttt gatattgatt ttaaaaagtc taatttaaca
    12121 gttaaaagaa cccttcaaag aacatatttt atagataaaa ccggaaatag agagcttaaa
    12181 gtattagagc aagagccaaa gacatcaaat tcttacagaa ctgtacctat tccaaaagat
    12241 gttttaaata aattgaaaga gcataaagta aatcaaaatt cggatatatt aaaggctgga
    12301 gaattatata gaaatgataa ttatgtattt tgcaatgaat taggtgcccc tattgatgat
    12361 aaaagacctt taaggaatct aaaatctata ttaaacagct tagatataga gcctataaaa
    12421 tttcatggtc ttaggaaaac ttatgcgact agactttttg agaatgatgt ccctcctaaa
    12481 actgtacaag ttttaatggg tcattatgat atatcaataa ctttaaatat atatactcaa
    12541 gttatggaag ataagaaaat tgaagctgta gaaaagttgg ataaaatatt ttcattgtaa
    12601 aaatcaaata tataaaaata ctctgatttc atatagttaa ttacaaaacc aaaataagga
    12661 tacaaattaa ttttatatta tcttgtatcc ttattcttgt ctagtttttt aaatatttat
    12721 cttggatagc ctttatgata cattaatcca ttttctaaca ttagttcttg ggctaaatat
    12781 atatgaccct tacagtgcat atctgatata ccctcactta taagtttata tgtttcagaa
    12841 gtatataaat aatccatact ttcttccaag ctcttacctg tttgtttaga aaattctaat
    12901 atgatttttt tatatagcga ttgtaacaat gtcttattag cttccataaa agctatacct
    12961 cctctttcaa atatttgttt atcctatttt gactaactat atatttatta gttatttaat
    13021 tagccataat aattcggcta taagatattt ataatctaat ctcaattata taaatctttt
    13081 tgccaatatt taataatcaa aatattgcac ttaattaact atcttataag tattgataat
    13141 aaaatctgtc ttcttaaata tacttaaata aaacttctat aattatatca aagtattaat
    13201 attcactctc tattgtctct cctacaagtc tattttctcc atttagggta tatactcctg
    13261 atatagttgg ttgtatgtat tttctatcca tatatggttc ttctaaaact cttttttctg
    13321 ctagcatcgt ccaaaataca ctatatcctt gttcattaag atattttaag aaaatttcct
    13381 tattaataaa gaatcctatc tcttcattaa gtaattcact actttcaaaa caaacaactt
    13441 caccataatc attatataga atcgaatctc cctgaccata tctcaatttc aacccataaa
    13501 atagagtact acaaggttta tgccatgtgc cagaaaagtc ttcttgaaat atgtcacctt
    13561 ctcgttcagt agtataacta taagttggca ataatacttt ataatccttt tctaagatat
    13621 tcttatgttc atctatttgt acccactctt ctccacaata atatgaattt tgaaaaaagt
    13681 aatatccatc tgcccaataa tattccttat tataaagagt ataattacta ttaggttcag
    13741 taagccatct acccataaag tcttttccct ttagagcatt cactattggt tctagttggt
    13801 catttttaat tatatagcta ttgattaata cccacatgtc tttttcagga tttttatagt
    13861 tcttattttt aaaatcattt tcctccttcc aagtatacca tccattaagt aataaaaagt
    13921 cttgattttt gtaaacacta tttaccatat catttatgct tggtaaatca ctaaaatctc
    13981 ctaaccactc attattaggt attggagaaa attgaaataa ttgattatgt actcttttat
    14041 tgttattatt atttattact gtcatgacag ttggatcaat attcctaata tctggctcaa
    14101 atgtaccctt acaataaatt tcttttttag taccataagc atctgtatac acttctatct
    14161 tataattatc agcagcttgc gctgcaagtt catataatgc aatccattga tatttctttc
    14221 ctattctttc atatttacta tctcttaatc taccattttg tactgttcta tcaaatttac
    14281 catgtttatt tacatcatat cccatatcaa aaactttctt aatagctata ttctttaaat
    14341 cgttatagtc tagacctttc catttatgga aatagtgttg gaacatatat cttccaaaat
    14401 ctccatacca tcctggttgt ccatctctag tatattctac ttccatagaa tttaagatag
    14461 tgttttgact ccaataataa tctttaaaat ctgatgcctt atagtcatac ttatatccct
    14521 caatttcttc atcagttggt actttaggaa aaattgattt atatggtggt tcaacattca
    14581 tatcttttaa tactgaacta tcaattttat attttgcata atctacaata ttttttgcat
    14641 aatctcttaa taaaatattg ggataaacat aatctacatc aaatatttta ttataaacat
    14701 aaactgccaa tgcctctatc atctcttctg attgctctga tacaacacat ccaaatgcaa
    14761 ctgcatataa tcgttcaata atatatgggt catctacatc ttcaaatgtt ttaagtaaat
    14821 ctattacaat atccattttc cctgttaata gatttacaag agcttttgta cttttatctc
    14881 ttaagtctct atttgaagaa attaaaaacg ttgcaatcat catagctgac aatctaattg
    14941 tttcatttga agtattatca aaaccttcaa aatcaaagca ccatcctaat aatcgcttaa
    15001 tagaagactc ttcttcttca taaacttcat taaatatagg tataaagata gcatctctat
    15061 ctgccatagt attttgtaaa atatatttta ctatataatc tgcatttaat gtatgattaa
    15121 cctttgtaga aattaagata agtacattat aaaaatctat tttataataa gatttaccta
    15181 aaactatttt attaatataa tctagtgttt tttcagtaat tgtagatttc ttacgccatt
    15241 ttagtgcatt gataaatgca ctaataacat tataatttgt ttctttattt ttaaaaactt
    15301 caaaaatttc attaggtata tctgagcctg tctcttcaga taaaacaatt gccaatactt
    15361 ctaatatatc ctcatattct actaaatatt tatacttatg tgaaaaatct actaccccaa
    15421 tttcttttaa ctctttaacc aacaaatttg catataaata atcttctaac ttctcatatg
    15481 tcacatgcat atattcttca tcatttaaat tgactgtttt attaactatt ccatttgcta
    15541 tgagttcatc tattatcaca ttgttaatct tatacttact tgcaatattt attataatct
    15601 ctacactctt gtttgcgggt attaaattat tcccaagacc atctccatat ttatatttaa
    15661 tcatttcatt aagtacttct gtaactacat tggcatgtct actataattg catgattcag
    15721 atattctaag attaagtata ttcaaataat ttttataaat atctgtaaaa ctaatagtat
    15781 ctaagttaat ctcttctcct ttaaaagttt cacacataat tctcaaaaaa agagggtttc
    15841 taaattcttg atttggcatt ggaatattag aataaggtat tccataataa tcaaaatact
    15901 ttttcatagc tttatgttct atactagaaa atccttgatg ctctataaaa accaaattct
    15961 cttttatctt gttattatta tctattaaag atggtatata ttcacttctt attgataata
    16021 ttagtccaat ccatggatat ttctttatct gttctacaat accatttaaa taatatttcc
    16081 aaagttcttt tccttgacct tcattcaatg catctataaa taatatcaca cgctgttgct
    16141 ctttttctcc tatttcatta agtatttcta ataattcttc aaactcacac tcaatttcta
    16201 atatttctaa catatgttta attggtgttt tatccaactt aaaatgttgc cctaaaaata
    16261 atatagactt atgcccatcc atatttcttt tctcaatagt atgtgcaatt atatgagatt
    16321 tccccatacc acctgcacta tgtaataaaa tataagggct attaactact tttatttcct
    16381 tagaatccaa atattttata tatacataga tatctttttg agtctgcttc aatttgtata
    16441 tttcatcttc tcttttttta cttttttcac agtcttcatt tataattata tttttaaaat
    16501 tatttattct atcatcaagt gctgcactta ttttttcaaa gtgctttttt aacaacttga
    16561 tatctaatct ttcattagct ttgtcataaa attgttgtat tatttcttct ataactagta
    16621 catctacttc cacttcattt attttctgtt tctttatact tgatagaact ttatctgttt
    16681 tttcatcaaa acgttgttta aattcttcat tttttcctaa tgcattaaac gtattttcta
    16741 aactcaattc tacattcaat tctggtaaat atctatctcc aaggtttttt atctgtatat
    16801 tattctgatt ttgaaaccat ttctctgtta atctacaaga taaattagtt aacctacttt
    16861 cctttaaaga cctatccttt aatcttctat attcatctgg caaaactatt tccaaaattc
    16921 gttcaagtat tattcttaca cactcatgct taccttcagg atacataatg gtttgtatat
    16981 aatactcatt ttctaactct attcgtctat gtttcttttt ctcactacta actggaataa
    17041 tagcataatg acccgttcct gcctctgata cttgctgtaa taattccaac ggtctatcct
    17101 tttccaaact acatccaaga aataacaact ctttacttgt atatacttgt gtaagcatct
    17161 ttctcaattc atcattacta tatgcttttt catattgttc ttttgttaac acaatagatg
    17221 ttgtaggctc tgtaatatcc ccatgaattt tatacaatac taattcatta tttctaagtg
    17281 cattatttaa tgcttcaaag tgacctggat gtgacactaa aactgtttta ttgtgtaatc
    17341 cataattttt ttctagtact ttatcataat tagtagttat aattaatcct gagccaaaaa
    17401 ttataggaat taaatagaca catttatcaa taaaatcgtc tttatctttt gcatccagat
    17461 aacctgcccc aaaaactttt tttaaatgtt tagaaaatct aactttcgcc aattcttcat
    17521 ataaaaattc tgcttttttc tcataatcct ctattttttc aaataaaatt ttatcctcat
    17581 cttctaaata ttcttcactt gtgttattta aaaatgtact ccatgaagga tatatgtctt
    17641 taaataacat agacatgcct gctccaatat atgggactac ataaccatct ttaattgcat
    17701 ttaccagttc atcaaaattt ttttgattgt aaggcttatt aaattccata atttcttcaa
    17761 atgtcattat tccctcctaa actatctctt aataatttca accataattc ctattttata
    17821 attttattat atcattccat tccatttttt tactacaatt ctatgttata gaatgaattc
    17881 acttacttac atttgttaat aatataaaac tttcttttaa gataattaaa atttatactt
    17941 ttaaattatg gataaaaatg gaatgttata acttttaatg tattactaat attaacaatt
    18001 ttaaaa
//
LOCUS       DAEHWO010000089        17761 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEHWO010000089 DAEHWO010000000
VERSION     DAEHWO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17761
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.089"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            47..382
                     /locus_tag="KNP54_003285"
     CDS             47..382
                     /locus_tag="KNP54_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894147.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            519..1796
                     /locus_tag="KNP54_003286"
     CDS             519..1796
                     /locus_tag="KNP54_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBF0894148.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1917..3305
                     /locus_tag="KNP54_003287"
     CDS             1917..3305
                     /locus_tag="KNP54_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBF0894149.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEEL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3676..4389
                     /locus_tag="KNP54_003288"
     CDS             3676..4389
                     /locus_tag="KNP54_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBF0894150.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKSKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4507..5376
                     /locus_tag="KNP54_003289"
     CDS             4507..5376
                     /locus_tag="KNP54_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBF0894151.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5531..6676)
                     /locus_tag="KNP54_003290"
     CDS             complement(5531..6676)
                     /locus_tag="KNP54_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBF0894152.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(7009..7785)
                     /locus_tag="KNP54_003291"
     CDS             complement(7009..7785)
                     /locus_tag="KNP54_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBF0894153.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8367..9341
                     /locus_tag="KNP54_003292"
     CDS             8367..9341
                     /locus_tag="KNP54_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBF0894154.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9439..9744
                     /locus_tag="KNP54_003293"
     CDS             9439..9744
                     /locus_tag="KNP54_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBF0894155.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9900..11060
                     /locus_tag="KNP54_003294"
     CDS             9900..11060
                     /locus_tag="KNP54_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBF0894156.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNLD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            11110..12012
                     /locus_tag="KNP54_003295"
     CDS             11110..12012
                     /locus_tag="KNP54_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBF0894157.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            12092..12985
                     /locus_tag="KNP54_003296"
     CDS             12092..12985
                     /locus_tag="KNP54_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBF0894158.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      13038..13219
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13447..14577
                     /locus_tag="KNP54_003297"
     CDS             13447..14577
                     /locus_tag="KNP54_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0894159.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTQEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14649..15674
                     /locus_tag="KNP54_003298"
     CDS             14649..15674
                     /locus_tag="KNP54_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBF0894160.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            15677..16873
                     /locus_tag="KNP54_003299"
     CDS             15677..16873
                     /locus_tag="KNP54_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894161.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(17001..17726)
                     /locus_tag="KNP54_003300"
     CDS             complement(17001..17726)
                     /locus_tag="KNP54_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBF0894162.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEYATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSVDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
BASE COUNT         6818 a         1981 c         3087 g         5875 t
ORIGIN      
        1 ataaaagttt gtttaataaa ttaaataaag aaaagaggag aataaaatgt acaacataga
       61 tgatatgata tataattgtc cagtagaagc tttatcaaat attttaggta aaaaatgggt
      121 ggctataatt atatggaaaa tacaagaaga taaaaaacga tttggagagc tacaaagagc
      181 tataccagac tgtagtaaga aaatgttagt tcaacaacta gattttttaa ttgaacaggg
      241 gattatagtc aaccaaaaaa agttggttaa taatgttgta gagtcaacat attttttaag
      301 tgaatcagga ttacgattgc ttcctgtcat ggaaaaaatg attatgtgga gcaataaaaa
      361 tttaaattgt gataaatact aaaatttact ctgtaagtaa tgaaaattta attaagctat
      421 gagtagaaaa atgtattaaa attacataat tttttagtta gattttaatt tagaaatggg
      481 attgtaatat tggaaataaa ataaggagga attttaattt gcaaaatgta aatttatttt
      541 tagtatttat agaaggtata gtatcattct tttcaccatg tatactgcca attttgccta
      601 tttatttgag tatattgtca aatagtagtg tagaaaattt aaaagaagga aagacgagtt
      661 ttataggaag ttctttattt aaaaatacta tattttttgc tcttggaatc tcaacaacat
      721 tctttatatt gggttcatca gtaaaagtat tgagtatgtt ttttaatgaa aataaagatt
      781 taataatgtt tattggtggg attataatta ttatcatggg attattttac atgggaataa
      841 ttaaatcttc aatattgaat agagaaaaaa gatttaatgt taagtttaaa gaaatgaaag
      901 caataacagc ttttatatta ggttttacat ttagttttgg atggacacct tgtattggtc
      961 caatattggc atctgtatta gtcatggttt caagttcaag taatcatctt agtgcgaatc
     1021 ttttaatagc agtatatact attggtttta ttttgccatt cataattaca gctatgtttt
     1081 acagtaaact atttaaaact atagataaga taaaatctaa catggaaatt attaaaaaaa
     1141 taggtgggat tatacttata gtatcaggaa tattaatgat ggtaaatgga tttggaagta
     1201 taagcaaaca ctttaatacg tcacaaaata gtaaaattga aagcaagcaa gaagaaaata
     1261 agcgagaaaa ttctactgat aaagaagaaa attctgatgg taatgatagt caaaaagact
     1321 ctaataatga caataatgat aaagggtcta atgatgaaga tagaataaag tctattgatt
     1381 ttactttaac agaccagtat ggtaaaacac ataaattaag tgattatgaa ggcaaagttg
     1441 tattcttaaa tttttgggct acatggtgtc ctccatgtaa agaagaaatg ccttatatag
     1501 aacaactgta taaagactat aataaaaata atgatgatgt agtaatttta ggagtagctt
     1561 cacctaattt aggtagagaa ggttcaaggg aacatgtagt taacttctta aaagaccaag
     1621 gttatacatt ccctgttgta cttgatgaag atggagcatt agcatatcaa tatggaatta
     1681 atgcttttcc aactacattt ataattgaca aggaaggata tgtaactcag tatattccag
     1741 gagctatgga taaggcaact atggcatcat ttattgaaaa tcagagaaat aaataaaagt
     1801 atttaagtat aagtttataa atcaatttaa ggttacaaaa aagtgcctaa ttgtaccacc
     1861 taaataatct tgttatagta aaagtataaa caatacaaga aagggttgaa ttttatatga
     1921 aaaaaacatt tgatgctata ataataggat ttggaaaagg tggaaaaaca ttagcagggg
     1981 atttggcaaa caggggatta aaagtagctt taatagaaaa gtcaaacaag atgtatggtg
     2041 gaacatgtgt aaatgtggca tgtataccaa caaaaagctt agaaaattca gcaaacagcg
     2101 taaaaacaaa gaatataaat tcttgggatg aagtacaagc tgaatatgag aaagctatag
     2161 ataaaaaaga aactttaatt acaaaactca gagaagctaa ctataataaa ttaaattcaa
     2221 atgagaatgt aactatattc acaggaatgg gaactttcat tgatgaaaaa acagttcaag
     2281 tcaaaactga aaatgaaatt tatgagttag tagcagataa tatatttatt aatactggtt
     2341 caagaccatt tatacctaat attaagggaa ttgaaaataa gaatatagta tatgatagtg
     2401 agtctcttat gaatctaaga actttaccta aaaaaatgac aattatagga gctggattta
     2461 taggtttaga atttgctggt atttatagtt catttggagc agaagttaca atattaaact
     2521 ctaataatgg cattttacca aatgaagatg ttgaggattc agaagaaata ataaaattac
     2581 ttgcaaagag aaatgtaaaa attgttaata atgcaaatat aaaagagatt aaagaagttt
     2641 ctgaattagc aatagtagaa tatgaagtag atggtaaatc taaagaatta acaagtaata
     2701 tgatacttgt agctacagga agaaaagcaa atactgagga gctagggcta gaaaatgcag
     2761 gtatagaatt aaatgaaaga ggatttatta aagtctcaga aactcttaag actaataaag
     2821 agcatatatg ggctatagga gatataaatg gaggtccaca atttacttat atctcattgg
     2881 atgattatcg catagttatt aatcagttgt ttggagataa gactagaaca actaatgata
     2941 gaaagaatat cccaaattct atatttataa gtccagcatt ttcaagagtt ggtcttaatg
     3001 ttaaacaagc taaagaaaag ggatatgaag tattagtggc aaagatgcca gtagaagcaa
     3061 ttccaagagc taaacagatt ggcaaggcag atgggtttat aaaaatagtg atagataaaa
     3121 aatccaataa gatacttgga gctagtatga tatgtgaaaa ttcaagtgag attatccatc
     3181 ttattcaatt agctgtagat ttagaagtag agtatacata tttaagagac cgtgtttatg
     3241 cacatccaac tatgacagaa gctcttaatg atattctatc tcctaatatg ataaaagaag
     3301 tataacataa gtttaatata taaacctaaa attatcatta taagtagatt ttagaaagag
     3361 gctatctcaa aaaatagaga taagtctctt ttttactgtt taaatgataa aaatatattt
     3421 gattttataa aagaagatta tcttatgaac taaaaagttt attttaaaac actacctatt
     3481 tatgttataa acttataaat ataatataga atctattatt ctgtattatt aagtggggtt
     3541 aagcgttata attaattata aatattgaat aatctaaatg gataagataa tggtattaaa
     3601 aattatctta aaaggtgaaa taatctgtat ttaatgtagt acagttatat ctttaaagca
     3661 aggtggtgaa atgatataaa taagatatct aaaagagggt ttgatgatag tgataaaaga
     3721 tggttttcaa gtaaagaatt aacaagactt ataaagtcta aagaagaaat agaatggtta
     3781 ttaaataggg attacaaaat agacccagtc gttacttttg ttggtgatag atatcagttt
     3841 tctataagac aaagagatgc attaaaaagg gcagtctgta ctgatgaaaa aaatattata
     3901 agacaatcaa aaaggctttc tctagataaa atcaaagaag ataccgtaaa tatagatggc
     3961 tttaatttga taatatccat agaggtagca ttatctggtg gtactctagt aataggaagt
     4021 gatggcaata taagagattt agcaggtctt aggggaacct ataagattat agataaaaca
     4081 gaagaagctt tgaatctgat aggtaaattt tttaataaat acaatgcaca gaatcttaaa
     4141 ttttatttag atgctccagt ttctaattca ggaaatttaa agtataggat attagagcat
     4201 gccaaaactt ggggaattga aactgaagta gaattagtaa aaaatgcaga tgttgtattg
     4261 gaaaaattag atagagtagt tagtagtgat gcagtcatag ttgacaagtg tataagttat
     4321 tttaatgtgg ctagaggtat aattgaagag tatattaaag aatgtaatat cataaattta
     4381 aataaataga taaatatagg tgagaatata taagtatatg tagcaatatt cttagtaata
     4441 caagtaaagt ttgaaaatag gagaacgaat acatatcgaa tttcataaaa tgttgtaaaa
     4501 agacatatga gaggatggat atgtgtgaaa ttaactaaac taaatattaa aaaatataga
     4561 gcacctatat ataaatatgc tttagcaaat gtaaatttga ggtctgctaa atctactaat
     4621 tcaagtatca taacagtaat acctcaggga gccaaaatgg aagtattgga tgaagaagat
     4681 gactggatta aggtgatgta caattctcaa gaaggatatg tgtataagga tttggtatca
     4741 gtaagcgaat atgcttggag taacttaaac ttaagagaag ataaatctac aacttccaat
     4801 ataattacag taattcctga aaaatctagg gttgaagtcc ttcaagtaga tggagattgg
     4861 agtaaggttg tatatgatga taaaatagga tatgttttta attatttttt atcaattgat
     4921 gggaataaac caaatgaatt agattataag tatttttata ctgacatgat taaatttgtt
     4981 aacgaaaata acattaaaag tactagcgat tatctaattg taacagacct tagaaataaa
     5041 tatacttata tttttaagaa agataatgga ggatggggac aactttacaa gtggcaatgt
     5101 actataggca agcctgagac tccaactata acaggtatat tttatataag tggaagaaaa
     5161 ccttcttttg gaacggatga gtattcagtt aagtatgcta ctagaattaa aggtggatat
     5221 tactatcatt ctgtactata tgattcaaca ggaagttata taatagatgg cagacttggt
     5281 gaagctctta gtcatggatg tataagatta agtacggaaa atgcaaagtg gatatatgat
     5341 aatataccag atacaacaac agttataatt cattaagaaa aattttgagt tttttattgg
     5401 gataataatt cttaaattaa tagaattata tattaacttc tcataaagag tactatttaa
     5461 aaagtgtaat aagagagtgc tattaacaaa acaaagatat tttgaggcac tctcttataa
     5521 atatacataa ttaagatatt ttcataaaca attctataat cttatcttta tcaaagaaaa
     5581 caggattagc accagcacaa gcatctttca tagagttttc tgcaagcaat tcaaaattag
     5641 gattatcaac acctacatct tttaaagatt ttgggattcc aacctcttca gaaagagctt
     5701 ttatcttatc tattacaaag tcaacacact ctttatctga tttattattt acatccattc
     5761 caataacttc agctattggt cggaatttgg caggggctga tttagcattt tcctcctcaa
     5821 ctattggaag tagcatggca ttacatactc catgaggtaa atcatataaa cctcctaatt
     5881 gatgagccat agcatgtaca tttccaagac ctgcattact aaaggcaatt ccatttaaaa
     5941 aacaagcata acacatttgt tctctagctt ctatgtcatt accattttta acagctcttg
     6001 gaaggtattt aaatatctgc tttatagcat ataaggcagt tgaatctgta acatcataag
     6061 caccattagc tactacagct tctatagcat gagttagtgc atccatacca gttgctgctg
     6121 ttaaattaga tggtttgcta atcattaatt ctgggtcatt tactgtcatt gtggctagtg
     6181 aattggtatc aaccattatc atctttacat gtctgtcttc atcagttata acatagttta
     6241 ttgtaacttc agcagatgta ccagcagtag tagttatagc tatgatagga agacattttt
     6301 tagaagtttt gttgatacct tcatagtctc taatatctcc tccattagtg gctaatatag
     6361 agatagcttt accacagtct tgtggagaac cacctcctat agttataacg aagtcgcaat
     6421 tttctgattt taatatttta agtcctttat tcacattagt tacagttgga ttttgtttaa
     6481 cttcatcata aacaacaaag tctacatcta tctgagataa aatatctgtt acttttttta
     6541 cagtaccatt tgaaactaga aatttatcac taacaataaa tgctttttta gttcctaatg
     6601 atttaattga atctttagct tcattaagac atcctttccc aagtaaattt attggtggta
     6661 cataataaat gctcataact aaaatctcct tttattttca ttgattttta tgtaaaaata
     6721 tatatctaac aattttcact aacttactca taatatatcg tatcttagat tgagatagga
     6781 ttgttggttc ttatataaga acttaattcg taattacgat tatgattaga atttaacata
     6841 gtatttttat catgtcaata aaaatataaa aaatattata aaaaaaacaa agttactgta
     6901 gttaaatcag caactttgtt tttatagtat aaatcaaata aatacattag tttaaaacaa
     6961 aatttttaat tattatgttt tgatatcttc catatacaga atattaatct aatttattac
     7021 aatgtcttca ttacgttctt ccatcattga ttgaatattt ttctgagcat ttaagagtaa
     7081 tttttttatc agttctattt tttcgtcatt agctctaaat aaaggcagtg ttacactaac
     7141 agcagctctt atacatccat tttttcttat tggtacggca agacatttta ggtgttccat
     7201 tgattcctca cactctgaag ctatttgtgt tctttgaact tcaagaagct ggtcgtataa
     7261 aacatcaaaa tctgtaattg atttttctgt aaaacctttt agaccatctg gatataagct
     7321 tattagtttt tccttgtcaa aatcacataa aagagctttt ccaagacctg tacaattagc
     7381 aggtattttt tttccaacat aagaaataag tctaattggt tctggagaat ctacttttcc
     7441 aatataaaga acttcattat tgtcaagtat accaagctga caagtttcag aacaggaatt
     7501 aactatatta gtcatttcgt caattatata gttaaaaata gttctttttt caaaaaatga
     7561 agaccctaat gtgtaagaac gtatccctat agaatatttg gatgtgtttt tatcaatagt
     7621 aatgtatttt ctagcattaa gtgtatgaac tataggaaag atgctacttt ttggagcatt
     7681 gataacatct gctatttctg taagagtata tccattttcg gattctgcta atgcttctaa
     7741 aatatctaat atcctagctg ttgggcgatg attatctgaa gtcataaatt tccccctctt
     7801 tttattaatt taaagtatta gaatatgttg attttagcac actatacgat attttacaat
     7861 gtagaaaata aatatgtaaa tttatatata aataagctct tgatttagat acagatagat
     7921 atttttttag actgtacatt aaggaataac taatttccaa aatgtaccta aagaaagtaa
     7981 gtgatattta gttatataat ttaagtaaat atatgcaata gttattttta tatgtaaata
     8041 tcaaaatatt atgaacttat attttatcta ttttttacac tgtataaaaa ctttatagtt
     8101 ttgaatacta tataatttta aatacgctgt atttttgcat ataaggaagt catttgataa
     8161 tatacaaggt attatcagaa agtttgaaaa aattttgaca aaaatttatt ttttttattg
     8221 actcataaat aggaaaatgc tatcattaat tcaaagattc gtaattaaaa acttagttct
     8281 taaatacgaa ccgaaacggc cgttagaatt aaagctaaaa acttaataag agtaattaaa
     8341 tatcatgttt taggaggatt aactttatga taatggattt tattaaaaaa attcctgcag
     8401 gtatgatgat agtgccaatg tttatagcag ctttcattaa taccttttgc ccagatattg
     8461 tacaaatagg ttcgtttacg acagcagtat tttcaagtgt tgggtctgca actataattg
     8521 gggttcaact ggtatgcttg ggaactcagc ttcaatttag agaaatgcca aaagttttaa
     8581 agagaggtgg tatacttctt ggttctaaat ttgctatagg tgctttgata ggtatactta
     8641 taggaaagct atttggaatg gatggtgtcc ttggtcttac aacattggct gttataagtg
     8701 cagttacaaa tagtaatggt agtatatatc tttcattgat gacttcatat ggagatgaaa
     8761 cagattgtgc aactatgagt ttacttactt taaatgatgg accatttttt acattaatag
     8821 ctcttgggac ttcaggtctt gcaaatgtac cattgttgtc attattggct gcaatagtgc
     8881 caatacttgt tggtatgata ataggaaatt ttgacaaaaa aatgaaagag tttttagagc
     8941 cagggtgtaa tttactcgta ccttttgtag ggtttgcact tggtagtagc ataaatcttg
     9001 caagtatact aaaaggaggt ttatcaggag tattacttgg attaatatct gtatttgtag
     9061 gaggtatatt tatagtattc tgtgataaat ttataggaaa acgtccagga tatgcaggat
     9121 gggctgtagc tacaactgct ggaaatgcaa ttgctgtacc tgctgctgtt gcattagttg
     9181 acccatcatg gcaaccatat gttgcaacag ctacaacaca agtggcagcc gcagtagttg
     9241 tcactgcaat attagtacct cttataacta gttggtgggc taagaagtat ggatgtccta
     9301 agttcccaaa acaaaatgag gatggtacaa taacagctta atttatatta cagtgagttg
     9361 ttggtaaaat aataaattct ttaattagat tttaggatat taataaaatt atattattta
     9421 taaaggagag caagaataat gataaatgca gtgataattg atgaaaaaga taatgttgca
     9481 gtagctattg aagcaatagc taaaggtagt gaaattagtt ttaaattaaa agacaaaaca
     9541 gtaaaaacga ttacagcact agatgatata actatttatc ataaattggc tataaaagat
     9601 atggcccaag gtgataaagt tactaaatat ggtgaacata taggagaagc aaatcaggag
     9661 ataaaaagtg gtcaacatgt acatattcat aatgttagaa gtgttagaga ggatttggat
     9721 aaacaagtta tgactaatat ataaaataat atttatagag ttataaaagt tgtattcatt
     9781 gattttagtg tcaaatagtt tttaaatagg tttttagctg tttgattagt gagtgtaata
     9841 aaaattataa tatataaaaa ttatagaaag tatatagact attttaggag gaaatcagta
     9901 tgaaatttta tggatataaa agaccagatg gaagagttgg tataagaaac cacatattaa
     9961 tattgcctac gagtgtgtgt gcatcagata caactagaat aatagcatca caagttcaag
    10021 gggcagttac ctttaataat cagaatggat gttcacaagt acattcagac caacaattaa
    10081 ctatggatgt tatggctggt tatgcagcaa atccaaatgt atatggtgta atagttgtat
    10141 ctttgggatg cgaaaattgc caaaatgatt tggtagttga tgcaataaaa gagagaacaa
    10201 ataagccaat aaaaactctt gtaatacaag aagaacatgg aactttaaaa actatagaaa
    10261 aagctgttcg ttatgctaga gaaatggcac aagaagcttc tttgcttaga aaagaagaat
    10321 ttccaatatc tgaacttata ctaggaactg aatgtggtgg gtctgaccca acaagtggat
    10381 tagcagcaaa tccattaata ggtgaattaa gtgataaact tgtcgattta ggagcaacat
    10441 caattttaag tgaaactact gaatttatag gtgcagagca tatactagct aggagagcag
    10501 taaatgaaga agtaaaagaa aaaatattac atatagtaca tagatatgaa aattcattaa
    10561 aattggttgg agaagaagtt agagaaggta atccatctcc tggaaatata gctggtggtt
    10621 taacaagttt agaagaaaaa tcacttggtt gtatacataa aggtggtcat agacaaataa
    10681 gtgaagtata tgattatgcc aaacaaattg ataagaaagg tcttgttata atggataccc
    10741 ctggaaatga tgcttcatct gttgctggta tggtagcagg aggagcacaa atagtggtat
    10801 ttagtacagg aagaggaaca ccatcaggaa atccaatagc accagtaata aaaataactg
    10861 gaaataaaat aacttttgca aatatggaag ataatctgga ttttgatgct agtccagtta
    10921 tatatggtcc acaaacaatg gaagaattaa cagatgattt gttaaatatg gttgtagatg
    10981 tagcaaatgg aaaacaatca aaagcagagt cccttggata tactgaaatg gcaatagcta
    11041 gagtatgcaa ctatgtataa tctttaagta agaaaataaa tacatagaat tttaataaag
    11101 ggtgagatta tgaagtttgt aagttttact gaaggagaaa atgaatgtaa aagaactgga
    11161 gttttttcta aagatgaatt atttattata gatgttaact ctttaaatct cagtagaaat
    11221 tttaaggatt taaatgaatt aattcaaaat gtatctagtg aagatattat taagttgaaa
    11281 actattataa atgaaagtac attctataat tatgatgttt ttaaaagaga gagatgtact
    11341 gtacatgttc ctatagaaaa accaatacat gatatcttat gtgtgggagt gaactataaa
    11401 gaccatcttg aagaaactca aactcacttt gatgatagtt ttgaagaacc acaaaaaacg
    11461 gtttatttta caaaacgtgt gacaaaggca ataggtccag aagatgagat agatggtcat
    11521 tttgagataa ataatcaact agactatgaa gttgaacttg gagtagtaat aggtaaaaca
    11581 ggtgttaata ttagaaaaga agaggtagaa gattatatct ttggttacac tgttataaat
    11641 gatatttctg ctagaaagtt gcaaaaagaa catgttcaat ggtttagagg aaaaggatta
    11701 gatacattta cctctttagg tccatgtatt ttacataaaa gtgcagttcc ttttcccata
    11761 aaacttaaag tatgtagtag ggtaaatggt gaagaaagac aaagttctaa tacagggtta
    11821 ttcatatcag acgtttcaga catagtttca gaactttcaa aaggtatgac tttagaggct
    11881 ggagacatta tagctactgg aacaccttct ggagtaggga tgggattttc acctcctcga
    11941 tatatgagta gtggagatgt agttgaatgt gagattgaga gtattggaat tttaaaaaat
    12001 tacattaagt aactgtttta atataattaa tattaaagct aaatctgatg tattaatgaa
    12061 catattaaaa taaattttag gagtttaaat tatgaaagca gaatttttga caccagttgt
    12121 tacaatattt gatgaagaag gaaatttaga taaagaaggt aataaaaaag tgtatgacca
    12181 tcttatagat ggaggtgtag atggactagt cataatggga agtactggag agttctttaa
    12241 tatgtctatg gatatgcaaa aagaacttat agatttagta actagtcatg taaataagag
    12301 agtaaaagtg tttataggta caagtcgtat gtgtataaat gaatctatag aactttcaaa
    12361 ctatgcacat aatagtggag cagatggtgt tatgataata agcccttatt atttctctct
    12421 tgatgatgat agtattgagt tattttatag tgaaatagct aagaatacag aggctgaaat
    12481 atatttgtac aattatccag atagaactgg ttatgattta agtccagaac ttacattaag
    12541 acttgcaaga aaacataaaa acatagttgg atataaggat acagtaactt tgatgggaca
    12601 taccagagat ttaataaata ctatgaaaat agagttccca gaatttaagg tttatagtgg
    12661 ttatgatgaa aactttatac ataatctaat gtctggggga gcaggttgta taggggggtt
    12721 atcaaattta attccagaag tttgctccaa atgggctgaa gcttacaata atagagatat
    12781 ggagaaggtt atagaaattc aaaaatatat taataaagca atggattttt acttaataac
    12841 caatccattt ataccagcaa tgaaaaaagc tatgaatatc agagggttac aaataagtga
    12901 ttatatgact gctccatttg taaaaccaaa tgaaaaacaa gtatgtgaaa ttaaaaaatt
    12961 gatgaatgaa ttaaatatat gttaaatcaa ccttgcaaag aggtcaacaa taaattacaa
    13021 ttatcttaat aaaaattaaa ttaaaataat actagggtac tatattagtt taatagggaa
    13081 agtgatgaaa attcactaca gcccccgcta ctgtatacgg atacgaaatc aaaatccact
    13141 gaaatttata aaaattttgg gaagggtgat ggaggaaaag ccgtgagtca ggagacctgc
    13201 ccagtattat ataagttcaa tttagggtgg agattgtaat ttataataaa atgaagtatc
    13261 aattcgtttt tgtaaagttg atatatgaac ttctccttat taaattagga gaagtttttt
    13321 attttattaa aaggttatac ttattaaaga tgactttagg ataactttaa taagtatact
    13381 ttaaaaagca tatattatta aagtttttta gccactcata aaaaataaga tattggagtg
    13441 aaagagatga aatttaaatc aaatgtttta aagcagtttt ttttaattgc tatggtaatt
    13501 tttatggtag gaggtcttat agggtgtagt aaaagtgaca aagagaataa acaagctagt
    13561 actggtaaga aattagaatt aaaatatgct agtggattta gtgttgaaga tttagaagat
    13621 ggaattaaaa aagtaactga tggagataat cgagaactga ttttaatccc aaagaagatt
    13681 aaaattcctg aaaaatataa aaatgctaat atagttagaa cgcctgtgga caatgtatta
    13741 atagcatcta caacacaggc ttgttctcta agaacaatag atgaactaga tagtataaaa
    13801 gccgtaacaa cacaagagca gtactggact attaaagaaa ttaaagattt aatgaaagat
    13861 ggaaaaatac attacgttgg ttcaaattta gcaccagatt atgaaaaaat agtagactta
    13921 aatcctgact taactatagt gagtagtggt ttatcagagg ctgatacaaa atttattgac
    13981 aaattaaaag aattagggct taattatgtt gtagacaatg agtataaaga gcaaaatcca
    14041 tttggaagaa tggagtggac aagtttaata gctgcatttt atgataaaga agatatggct
    14101 actagtgaac taaataaaac tgtacaaaag gtagaagaag taagtaaaaa aataaaaaac
    14161 aaagctaaac ctaaagttgt atgggcatct gtatatgaag gaagtgctta tatagctcct
    14221 aaagattcat atgtggataa tatgataaaa atggctggtg gaataaatgc atgtgcttca
    14281 atagattcaa atgaagggcg agtaagtatt gaacaattgc atgaagttgc aaaagatgca
    14341 gatatatttg tatactcatc aagttcagat tatgcaccaa atttagattc tataaaatct
    14401 agtgcacctg tattggctga tttggatgtt gtaaaaaacg ggaacctatg ggtgtttgct
    14461 ccagattatt atcaatcagt agataagaca gacgaattaa tagtagattt agttgagatg
    14521 ttccacccag gtactacagg tgaaaaaatc aaacattata taaattatga taaatagtac
    14581 agagaggaca caaaaagata ggttttatag attttagtta atatagcttt gctaaaagga
    14641 gtatacaaat ggattttatc aataaaatga gaataaggaa tacgacaata tttatagtat
    14701 taattataag tatgatactt acttttttag tgtgtgtagc atttggctct gtaaaaattg
    14761 aatttaaaga agtaatagat gttgtattaa gaggtatgga taatacagaa cattataaaa
    14821 taatatacaa tataagaatc cctagagtac ttgcaaccat ggtaggtgga gcatgcctag
    14881 cagtatcagg tattttatta cagatatttt ttaaaaaccc aatagttgaa ccgtatatat
    14941 taggagtatc ttcaggttct actttatcag tagctctcat gattttggga ggatacacat
    15001 tgggatttga gagtgtaaat tcaatgagta tatttgtagc agcttttata ggagctttaa
    15061 ttgtaatgtc tatagtcatt ttatttgcaa ataaggtaaa gaatataaca actcttttaa
    15121 taataggaat tatgaccgga tatgtatgta gtggtataac aaatgtgtta caatcatttg
    15181 caaatagtga taaattaaaa gaatttacta tgtggtctat gggaagtttt tctggattta
    15241 catgggaaaa ggtagaaata cttataatag ttggtatatt aggtcttttg atgactgtat
    15301 tcataataaa acctttaaat gcttttttac taggagaaga gtatgcaaaa agtattggca
    15361 taaatataag attttttaga gttttgatag tatttatatc tagtatatta gcagcaatag
    15421 tatcagcatt tgcaggacct atagggttta ttggacttgc agtgccacaa atttcaaaaa
    15481 tgatatttaa aacatcagat aatagagttt tgataccagt agtaatattt ttaggcagta
    15541 tagttacagc tctttgtgat ttaatatcaa gagtaatttt atcaccagta gaattaccaa
    15601 taagtacaat aacatcttta ttaggagctc caattgtagt aatgttattg gtgaaaagga
    15661 aggatagggc ttagacatgt tgaaaactaa taatttaagt gtaggataca ataacaaagt
    15721 tgttataagt aatataaatg tagaagtaaa aaatggagaa atactatgtc ttttgggaag
    15781 taatggagct ggaaaaacta ccctattaag gtccttatct aaacttatat caccaataaa
    15841 aggtgaaata tatttgaatg gtgtaaacat aaattgtata tcaagaaaag cattatcaaa
    15901 aaaaatggct ttagtactta caaatagatt attaggtgat ttaatgactg tacaagatat
    15961 agtcaatata ggaaggtatc catatacagg attttttggg agtctatcta agaaagattt
    16021 aataatggta gatgaagcat tggagtctgt agatgcctta catttaaaga aaagatattt
    16081 tgatgaacta agtgatggag aaaaacaaaa ggtgttggtt gcaagggctc ttgttcaaga
    16141 accagaaata attatattag atgagcctac aactcacttg gatataaaac atagattgga
    16201 actcataaac atactgaaaa aattaagtaa agaaaagtca atatcagtaa tactttcatt
    16261 gcatgaaata gacatagcat taaaaagttg tgataaagtt gctcttataa aaaataataa
    16321 agtcatagct tatggccagc ctgaagatgt agtagatgag gatattataa attcgcttta
    16381 tgaattggat gataaaaact ttaatagtct tttaggttca gtagaaatta gtaataaatc
    16441 taaaaatgaa gtttttataa ttggtggtgg gggtaaagca acaccaattt atagagcttt
    16501 tactaaaaaa ggtataggtc tgtattctgg aataatacat gaaaatgata ttgattatga
    16561 aattggtaga actatgggga taaagatgtt tacagaaaat ccatttgagc ctataagtga
    16621 tgagagtttc gatttggcta ttagaaattt aaatgattcc aagattataa tagatacagg
    16681 atttagtgta ggagagacaa ataagaggaa tatagatatt ataaaagaag ctttaaaatt
    16741 ggataaaaaa gtttattctt ttagaaatag agatgagagt aagaagtatt atgacagttt
    16801 ggatagtaag atagaacata tagataaagt ttctcaaata atcaatagtg cagatataaa
    16861 taatttatta taatttatga aataaaatgt acttatgtgt tatagaaaaa agagtataga
    16921 ttataatttt tttgaaatta caatctatac tcttttgtta ttttgtttat gtatttatat
    16981 atttataaaa ctttagcatt ttatagataa ccaatagctt cctctctagt taaaaaaaag
    17041 tgaatccctg tagtcgattc tttccatcta ttttcattaa aatcttcagc tacaatcgtt
    17101 tctcctactc tatatataaa attttcatca gcatatgcac gagcactttt aaaagattct
    17161 ttaccatcta cactagtaat tgacagtact tttgccttat cacatctaca agcatttgat
    17221 gtagcagaca ctctttttgc gtcgctgggt attaataatt gtaccattct aaaattaaaa
    17281 cattttttat agcctataaa tgctcctgtt tcaggacaat acaatttaaa aaaacgagta
    17341 ctttcatctg atattactcc atttaaagta gcatattcta aattggaatt ttctaaatta
    17401 gctcctctaa tatctgagtt agataagtca caaaatctaa aacttgcacc acttaagtct
    17461 gcatttttta atatagaatt ttttaatgaa caatccgaaa gataagaatt attaaaaata
    17521 gagttttcta aatctgcttt ttctaaattt aaattgataa ggtcagacca cgaaaagtca
    17581 atattactta agcagtatcc tcttaagtcc atattttcta atcttaattc ttttaaatct
    17641 gccttttctc cagcattatt gtttttaagc cataaataat gtttctcaag tgttttttct
    17701 aattcttgtt tagaaatagt tttcattaaa atcaccttca taaatttatt tttatatatg
    17761 t
//
LOCUS       DAEHWO010000090        17410 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEHWO010000090 DAEHWO010000000
VERSION     DAEHWO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.090"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(261..785)
                     /locus_tag="KNP54_003301"
     CDS             complement(261..785)
                     /locus_tag="KNP54_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBF0894163.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(850..1602)
                     /locus_tag="KNP54_003302"
     CDS             complement(850..1602)
                     /locus_tag="KNP54_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBF0894164.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1633..2931)
                     /locus_tag="KNP54_003303"
     CDS             complement(1633..2931)
                     /locus_tag="KNP54_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBF0894165.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2948..5212)
                     /locus_tag="KNP54_003304"
     CDS             complement(2948..5212)
                     /locus_tag="KNP54_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBF0894166.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5467..6285)
                     /locus_tag="KNP54_003305"
     CDS             complement(5467..6285)
                     /locus_tag="KNP54_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBF0894167.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6278..6976)
                     /gene="cbiQ"
                     /locus_tag="KNP54_003306"
     CDS             complement(6278..6976)
                     /gene="cbiQ"
                     /locus_tag="KNP54_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBF0894168.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASINMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6979..7263)
                     /locus_tag="KNP54_003307"
     CDS             complement(6979..7263)
                     /locus_tag="KNP54_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0894169.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7253..8005)
                     /locus_tag="KNP54_003308"
     CDS             complement(7253..8005)
                     /locus_tag="KNP54_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBF0894170.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8187..8379)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8511..10283)
                     /locus_tag="KNP54_003309"
     CDS             complement(8511..10283)
                     /locus_tag="KNP54_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBF0894171.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDVILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10297..11226)
                     /locus_tag="KNP54_003310"
     CDS             complement(10297..11226)
                     /locus_tag="KNP54_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0894172.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11447..11632
                     /locus_tag="KNP54_003311"
     CDS             11447..11632
                     /locus_tag="KNP54_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBF0894173.1"
                     /translation="MKYGCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKNA
                     EKPVDGRTKRRKEVQYE"
     gene            11625..12326
                     /locus_tag="KNP54_003312"
     CDS             11625..12326
                     /locus_tag="KNP54_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894174.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12328..13251
                     /locus_tag="KNP54_003313"
     CDS             12328..13251
                     /locus_tag="KNP54_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0894175.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13408..14331
                     /locus_tag="KNP54_003314"
     CDS             13408..14331
                     /locus_tag="KNP54_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894176.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHAKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSEYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14324..15061
                     /locus_tag="KNP54_003315"
     CDS             14324..15061
                     /locus_tag="KNP54_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894177.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANTALGRRK"
     gene            15072..15845
                     /locus_tag="KNP54_003316"
     CDS             15072..15845
                     /locus_tag="KNP54_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894178.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16386..16994)
                     /locus_tag="KNP54_003317"
     CDS             complement(16386..16994)
                     /locus_tag="KNP54_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBF0894179.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(17172..17288)
                     /gene="rrf"
                     /locus_tag="KNP54_003318"
     rRNA            complement(17172..17288)
                     /gene="rrf"
                     /locus_tag="KNP54_003318"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         5621 a         3013 c         2195 g         6581 t
ORIGIN      
        1 gtgttttcca catattttat atatttattt aatacattat tatttaaaaa taaatatata
       61 aacaatcata ataaaatttt tttaataaaa ctttattttt tagttaaaat catacaatat
      121 atagatttcc acaatacaaa taaattaaaa agtgaaatgt atttgtctaa aaacataata
      181 acatttcact ttatcctcat ttttaagtaa tatatatttt taatttttat ttataactaa
      241 atctagtttt tatataaatt ttagtttttt tctacatctg agtaatctat tccaaaagtt
      301 tctacagtaa cagatttcat aacttgtgga gtttgtggct tatcagctga atctgttcta
      361 actgatgcta tttcatcaac tgtatccata ccttctatca ctctaccaaa acctgcatac
      421 tgaccatcta agtgtggtga gtttttatgc attatgaaaa attgagaacc agctgaatta
      481 ggtgccatag ttctagccat tgatatgact cctctttcat gttttaaatt gttagtaaat
      541 ccattaccac taaattcacc ttttattgag tgacctggac cacccattcc tgtaccattt
      601 gggcatcctc cttgtatcat aaatcctggt attactctat gaaatattat tccattgtaa
      661 tatccttcat ttactaatga tacaaagttt ttaactgtat ttggagctat atttggatat
      721 aactcaattt tgatttcttt tccattttcc atttctatag ttactatagg atttttattt
      781 tccataattt attaccttcc ttttcattag ttaaattaca taattacatt tattatatta
      841 tactctaaat taaagtctat caagtatatt ttttcctatt tcatatcctt cttgataaat
      901 agttttacaa aactcatcat caaagttaag cgtgtcttta ggagcaaatt gagtattagg
      961 tctaactact attattttat cttcatcata tactttttta atatcttctg gcaactcata
     1021 attatatttt gtggatatta aaataatttt atccacatta tccccaatta atggttcaat
     1081 taatgcactc ctaattaaac ctccatctaa tttgaaacca tcataaattc cttcttgcac
     1141 atctttcaca aattgttctt taaatccaag agttgcgttt ggatttgatg gtaacaaccc
     1201 actgtatgaa atgctgataa tggcttcatt acgaggcatt tttgatacgt caacaatctt
     1261 ttctgatact actttattat caacttcaac ataattaaca taaaagttca tttcttctat
     1321 attactatca tctagttccc ttaggttgtc tatagcagga gaattatcca cagtattatt
     1381 tactattttt acatttccat tctggatatc ttttatattt gtccacattt tctccaagtt
     1441 atcaacattc cctgtgtaca aataatatcc atttattgct cctattgatg tccctgaaat
     1501 cgaataaaat ttatttattc ctccatcata caaggcttta actactcctg cttgataagc
     1561 cccttttgct cctccacctt ctaaacataa tcctaatttc atagtctcat ctccaaattg
     1621 tttatcttat atttatattt caaaaaactt actaaatgtt ttatatatac tatagtggtc
     1681 ctcaacattt cctaattctc ttatagaatg cattgctaaa attggacttc ccacatccac
     1741 agatggtata tctatatgag tagaagatat tggacctata gtacttcctc ctctttcatc
     1801 tgacctatta acaaattctt gatactcaac attagcttct ctacatatat ttttataaat
     1861 agctatagaa tatccatcac tagtatatgc ctgactagca tttatcttta taaccggacc
     1921 ttttcccatt attggtttat tagttgggtc atgcttttct ggaatgtttg gatgaatagc
     1981 atgagctaaa tctgatgata tcataaaaga tgaataaata gactcaaaga atccctctct
     2041 atccttaccc attgatatgc aaattctctc caatatattt aacaacatgt ttgaatctgc
     2101 accttgttta gtagagctac caacttcttc attgtcaaat acagccatta catttacacc
     2161 atgttgacct ttagtattaa caagagcatt caaactagca tgtaccattg caagattatc
     2221 ttgtctccca atagatataa attcatcatt agcccctatt aaacttcctt tttcaaattc
     2281 atataaaaat aaatcaaaat ctataatatc gtccatattt acatctaagt tagatgctat
     2341 ttgctttata agaaaattat ctttttctaa tgtatcattt aacatcccaa ctaaaggtaa
     2401 catatctttt tgcttattat atgagtgacc atcatttata cttctattta aatgtattgc
     2461 tagatttggt attatacaaa ttggcttttt aaagtctata agcctttcat ttggttttaa
     2521 tatactatca ccttttaaaa ctactctacc agctatccca agaggtctat ccaaccatgt
     2581 acttaatatt gctcctccat agcattctgt atttaacttc aaataagatt tttcagcttc
     2641 tatttctgca tttggtttaa tactaaatgt aggagaatct gaatgagagc ctattattct
     2701 aaatccatct ctttctatac cttctgaatt tactacaaaa gctactatag ctgataaatt
     2761 cttagtaaca taatactttc caccaactct tagattccat ctttgattca aaactaattc
     2821 ttcaaatcca tttttatcta agatttcctt agtactctcg actgcatgaa aagacgacgg
     2881 actatcatat atgaagtcta ttaagttttt agcaaagttt atactatcca ttcctcattt
     2941 acctccatta taaaatattt agtgttgtat attctttatt tattttttta attccctgtt
     3001 ggtcaaaagc tatagtaaca tctgtaccaa ttatagaaac cactgtccca accccaaatt
     3061 taggatgatg taccttagaa ccaagtttta tatcatctgg attagtttct ttattagaat
     3121 cttttattgt agcattaact ttatctgcaa ctttagattt gcttatagta ctcatatact
     3181 ttttagtata tttatctaac atattataac ttgctttaga atagcttagt tcttttttta
     3241 ctttgtacaa tctttctata cattcttctg gcagttcttc cataaatctt gaagctattg
     3301 caacatttgt tttaccatat aatgttctct tctctgtcaa tgacatatat agctcttctt
     3361 tagctctagt tataccaaca taacaaagtc ttctctcttc ttctatttgt gaatcactca
     3421 tagattttat agctcttgat ataggaaata acccttcttc catacctgtt aaaaacacaa
     3481 cagggaactc taaacctttg gatgtatgaa ttgtcataag cgaaacccta tcattgtctt
     3541 cttcatcatt tgattcagat gtaagtgcta tacttgttag gaatgtctct aagtctttat
     3601 tttcataagt atcatcatta ctactttcaa actccaaagc tatagaaata aattctctca
     3661 aattatcaat tctgtcttga gcttcttcac ctttgcctgt taaatctttt tcatttttat
     3721 ttcttatctc tacaagctcg tccatatatc ctgtagtatc caagactttt tctataagtt
     3781 tgctaacagg ataaacttct tttatagttc taagagtccc tataatatca acaaatccac
     3841 ttatacttgc ccttgcctta gtagatatat ctgaatttgt ttctatatca attaatactg
     3901 agtatatact ttcctgtttt aagttagctc tatcttcaat tttttctata gttctaagcc
     3961 ctatacctct tctaggaaca tttataatcc tttttataga tatatcatct tgtggatttt
     4021 gaataactct taaatacgcc aacaaatcct ttatttcttt tctctcatag aattttgtac
     4081 caccatatat attgtatgga atttgacttc tatttaaagc gtcctctaca ggtcttgcct
     4141 gtgcatttgc tctataaagt actgcaaaat ccttataagg tctattttct tttctagcta
     4201 tttgtgcaat tgaatcagca atgaaatcag cctcttctat ttcactacca gttaattgta
     4261 tctttataag ttctccttct tttttttcac tccaaagctt ttttcttttt ctttctatat
     4321 tattagatat aactttatta gctgcatcta atataacttg tgtagaccta taattttgtt
     4381 ccaactttac aacatgtaca ttgtcataat ctttctcaaa ttcaagtatg tttcttatat
     4441 ctgcacctct ccatccataa atactttggt catcatctcc aacaacacaa atattttgat
     4501 gttctcttgc taataatttt atcaattcat attgagcttt acttgtatct tggtactcat
     4561 ctaccattat gtatctaaat ctacttctgt aatatgctaa cacttcatca ttagccttga
     4621 aaagttctac agttttaagt attaaatcat caaagtcaag tgcactattt ctttttaaac
     4681 ggtcttgata tagcgcataa atatctgcaa tcttaaccat tctattatct gccatattga
     4741 tatctttaaa ctgctttgga gtataaagtt tgtcttttgc tcctgaaatt gcacttataa
     4801 ctgcttttgg ttcaaacact ttatcactta aatttaattc ttttagacag tctttaacca
     4861 atgtaacttg gtctgctgaa tcataaatta caaaacttct attgtaacca atcttattta
     4921 tatcttttct tagtatacga acacagcaag aatggaatgt acttatccac atatccttag
     4981 tttcaggacc tatattttgt tcaactctct ctctcatttc atttgcagct ttgtttgtaa
     5041 atgttatagc taatatattt ggtgcttgta cacctttatc ttctataaga tatgctattc
     5101 ttgttgttaa taccttagtt ttacctgaac cagcaccagc cagtataagt actggacctt
     5161 cagtcttttc tactgcttct ctttgagcag gatttaatgt atctaaattc atatttctcc
     5221 tcctgttaac agccataaat atattttaat ctaaaatatg aattacttca aattataatt
     5281 atgtattata ttaatagatt atttccaata tattacaatt aaataacatt tttccatata
     5341 atttatttca ttgtttaata aaaaaaataa ccttatgatt tggggaatca taaggcacct
     5401 ttaaggggtc taggttaagg gttattatat ataaatctat ttttttaaaa taggtttagg
     5461 gcttaattat ttatttgtat taagttctct ttccttccaa tacttataca aatcttcttc
     5521 tttcttaaat aagggtaaat tcatatttct atgtactttt actaaccatg gggattctag
     5581 gccagcttgt ataatattat tttcatttat aaacacattt tctgcttttc cttcatcaat
     5641 caaaatcccc ttatccaata catatatgta atcacatatt tcatacatta aattcatatc
     5701 atgactggat attactattt ttatattatt tttatttaat ccctttatta tatctacaat
     5761 agacctagta cttactgggt ctaaaccagc tgtaggttca tcaagtaata caatttcatt
     5821 ttccattgct ataactgatg ctattgccac tctttttttc tgtccatagc taagaaaatg
     5881 tactggcctg tctataaaat ctattccatt aacagctact agagctttgt ttattctctc
     5941 tttaattgtt ttttcatcca taccaatgtt tctcattgca aaggctatat catcatatac
     6001 ttttgaataa aaaatttgtt tttctgggtc ttggaagaca atacctacat tttttctaag
     6061 gttgtataaa cttctcttat catattttaa cttttcttct ttaaaaagaa tttctccaga
     6121 tgtaggcttt aatataccca ttaaattcat aaataatgtt gattttcctg aaccatttga
     6181 acctattata cctataacat ttccctttga aaaatccata ttaatgttta atagtgcatt
     6241 ggtatttttt tcatattgat acgttaaatt atttatttta aacatcatta tcccctacta
     6301 tgtgaaattt accatcatac aattttatgt ctaatgatat acacatatca tcataccttg
     6361 tcataagtct tttgtacagc atacttccaa gaatacctaa ggatttatat gaagttttta
     6421 aatttatata tccaaatctt agctcttgtg acttgtatat ttctgaaaat tcttctaaaa
     6481 atatgaatat aaacctatat attaacattg ataactcgac aaaagtgtca ggtaaatgaa
     6541 gttttttaaa aaagaatatt aattgattaa aaggtgttgt aagtatacaa aaatacacac
     6601 aagtcaaaca agacatcgct ctaaataaca catgaataga catgttaata gacgcctttg
     6661 atattcctac attaaaacta aaaaattcaa aactatataa taaatctgct ttattaaaag
     6721 atatatttac aagagttatt cctatactaa gaaataaaaa gtacattggt attctaagta
     6781 attttaaata attttttaaa tctattccag ccacacaaac aaccaaaata ctcattaaaa
     6841 tcataattcc acttaaaata aatatatttt gtattaccat agaagcaatc agaaaaatta
     6901 ctcctatggc tacttttttg tttggattta ctttactcaa tctatttgta tatgcatatt
     6961 tatcaattat aagcatgatt aacttctctt tcctttttga agacctaata tgtatcctat
     7021 tacaccagcc cctaaagctg cttgtgcaga gaataataaa ctttctattt ctccacttgg
     7081 tggctcatat ggactgctaa accatggttt gtaatttgga tttatcttag taatttcact
     7141 ttcagcttga ccatctgctc ctccatattc agcacctgag ttgacaagta atgggaatat
     7201 aataagagct actactaata aaagtaataa tatgttagtt tttgtttttg ttttagcact
     7261 cattagcttt aactccttta tcattatttt ctagtatgct tttttctccg ttttctgtaa
     7321 ttaaattata tacaattaca gtaagtatac cttctgctat tgctattggt atttgagtca
     7381 taaagaaaat tcctaaaaat ttaattgctg aagccattac cccacctgat gggtctggga
     7441 aagccagtgc taattgtatt gaagttattg tatatgtggc taagtctcct attgctgctg
     7501 caagaaatac tggaatagca ttatttccat cttttttctt taaagcctta aatattagga
     7561 atgatacgat tggccctatt atcgccattg aaaaagcatt agctcctaaa gtagttattc
     7621 ctccatgtgc taataacaat gcttggaata ttaaaactat agttccaaga acaaacatta
     7681 cgcttggtcc aaacattatt gctccaagac ctacaccagt aggatgtgaa caacttcctg
     7741 ttactgaagg tatttttagt gctgataata caaacacaaa tgctccacat aaagctaata
     7801 atactttctt tttagggtct tgctttacta ttttacctat tgattttaat ccgaataaga
     7861 aaaatggtat aaatataact ccccatgcta tagaccattt tactggtaag taaccttcca
     7921 ttatatgcat tgcatttgat gtaactggag ttaaaatgat taacataagt gcagctataa
     7981 cccctaattt aatattctgt ttcatcttag tatccctctc tccctttcta ataattaaaa
     8041 cataataata catgtctgat ttatttaata aaataaaaaa gcctaactcg atggttaggc
     8101 ttctaatttt ccacaatcta aatacaaaca cataaaacaa acatatctgt ataattatta
     8161 taagaaactt tctccatccc cgaagaaatt actttaatat tttaggcagg tctcctgact
     8221 tagcttcatc ctactccttt tccttcccat gagatataaa aaatatcatc atagtggcta
     8281 acaaaagttt cgtctgcatc acagtagcgg gggctgtaaa ggaatttaac ctttttccct
     8341 attaatcttg cttaaagaac ctataatatt atatatttaa tttttaaatt attcttaaat
     8401 cattttctat ataaatcatt gtataccttt tctgtgaaaa tttctacatt ttttataaat
     8461 tttattcatt tttatatttt tatgtatata aattcttttt tgtaagttta ttaatttcta
     8521 attatcttct ttaaatacat tgaaactaca tcagaaaatc tagttatatc tcttgaatat
     8581 ataaaatcat ttccatatat taatctttca gcttcaagtt ctgattcttt tcctgtaaat
     8641 actcctaata ctaatatatt ttgctttcta gcttttctca cttcattggc tgtatctctc
     8701 aaaccaacta tacccctata agccttttct cctcttaatg ttctctcact actttttcct
     8761 atctttacat catttggtct tccatcgctg agaactatca ggattttatt ttcttcatct
     8821 ctatttatta gaccactaca tatagatttt attgccaaac catctctatt attaccagca
     8881 caaaaatatt caaatatatt ttcactattt tttatactat catcataatc tttaaatctt
     8941 tttaatattg tatagtctaa aaaactagaa aatcccatca ctctatttgg tatgccaact
     9001 tctgttagag catttgcaat tatgtaagct tgaattgcca catttccctg atttctactt
     9061 tgagagccac ttgcatccaa taatatatca ataacgtatt tccctttttc attttctata
     9121 tctttataaa atattttatt attattactt ctaccaactc tccaagctct attggctaat
     9181 atagtaccac aatcagaata tactctactt ttagcatttt cttctattaa aattcttgac
     9241 agactttctt ttaatctctt tatttgctgt ctatacattc tagcatgttc tctaaatttt
     9301 cctaaattat tttctttttg tcttgttaca tattttagtt gaaatacatt attacactca
     9361 cttctaagaa ctccatctgt aaagtgtatt ctacaacctt catgaacatt tctacaattt
     9421 tgtgtctcaa tttttttaat ttcaccttta ctcaaataag tttttccata ataatgttct
     9481 atttttgaat atatcttatt tgcagtgtct tcatcaacat atataactcg gtctgctgaa
     9541 ttgctacatt tagaatcatc aaaatcccct acaccttcta caagcatgga tgaagatatt
     9601 gaatctatat cactttcaat aatattttct tcttcatcac tataaagttc ttcatacatg
     9661 aaatcagcaa atgtatcaaa atttacttct acactttcta cattattttc atcaataaga
     9721 ctattttctt ctccatttaa tatgtattca aaataagtta aatatataac atctaatgct
     9781 tttaaaatct ccataatatc ttgattggta tctatatttc ttatatcatt aactattctt
     9841 ctagtcatac tatctaatgc tgggtgcttg tccatactat aaagtacaaa tgtgtattta
     9901 attttatcca taatattatc attgtgtatt ttggtaaaac gtgaaacaat atctttataa
     9961 gcattccttc ttatgtcttc tatccctggc ctgtctttaa tgaccttttc ttcaactatt
    10021 gtatttaata taacttgaat tagacctagt ataacatctt tgttgtatcc ttttcttatt
    10081 ctatttgtaa gatatttttt aactatatcc caatctacat actttcttct agcacctgca
    10141 attattgcga aatatagacc tatttctttt gaagagtaat ctttttctga tatatctata
    10201 ctttcattgt aatcaccagc tattgtccat gataggttat tagctctatt ttcaaattca
    10261 taatcatcat atatccattt cataatctca cctatattaa atatgactta ttggaaacac
    10321 atctatactc tcccatttat taggtattct agttttaatt acatctccaa ccatttcttt
    10381 ctcatataca tcaaaagtct ttcctgtaag tcccatatta attgcaagag ttggttttaa
    10441 tcctcttctt atagtcttaa gagatgccat aagaccacgt aaatcaatag ctttactaga
    10501 tatctctcca ttttgagact tcaattgtaa atctaaaaat attcctgcaa agtgtattaa
    10561 tttttcttca tcagcatctg aaaattcatt ttttaaaatc atcattaact tatcttcttc
    10621 tataggagga atatctatta ccataaatct agataccagt gcttcattaa gttcttttgt
    10681 tcctgcatat tcataattca tagtcccaat aaatcttgtt gctggatgta gattgactct
    10741 ctcataccca ggtacatcaa ttattcttct atagtctaaa gctgaatgta ccacaactat
    10801 agcatcattt tttgccatat taatttcatc aaacacccca aaacctccat taatagcaca
    10861 ctcataaact gagcctcttc taagtttaac ttcattgtct ataaatgtat ctgtacctat
    10921 aagtgttgaa ctgtctgtat ttatatgaaa tgatgtattc cactgaggtc tattaaatat
    10981 ttcccctaga ttatcagcaa gtaagttttt tcctgttgcc tttggtcccg ataataatat
    11041 attttcttct tctaaaatag ctgctataca catagacaag atatctttac cataaaaata
    11101 agttttagac tttgttactc tgtattctaa atctttttct aaaccataat aatttctaaa
    11161 atacagtaca tcttcaataa gtttttcatc taccccttgc acccttagat tatctattat
    11221 atccatattt ttaccccttt tatataaata gtatttgttt catttcttat caccatttta
    11281 gcataaaagg atataagcta aaattgattt tttaatctcc ccattttaag taaaaccatg
    11341 caccatttta tcactacaaa attaagagta ctacttactg atatttcttg attttgttcg
    11401 tctatacgta tataatatat gctgataaat tatgaggaaa ggatgattga aatatggatg
    11461 cccagaagta gcaaaaaaat ggggtatttc tgaaagaaga gtacaaaaac tatgtgaaga
    11521 aagtcgcata ccaggagttt caaaactcgg gtatatgtgg ctgataccaa agaacgcaga
    11581 aaagcctgtt gatggtagaa caaaaagaag aaaggaagta caatatgaat agcgttttga
    11641 ttatagatga tgacaaagaa ctttgtgctc ttatgaaaaa atgtgttgag caagaaaatt
    11701 tatctgctat tactgcacat tgtggtgcag aaggtctaca tttggtcgat aaaaatagac
    11761 acacactctc tcttgtaatt ttggacataa tgatgccaga tatagacggt tttcaagttc
    11821 tgaaaaaaat tagagaaaca agtaatattc cagtaattat gcttactgct aaaaatgacg
    11881 aggatgataa agtttccgga ctacgtttag gtgctgacga ttacctaaca aaaccgttca
    11941 gcataaacga acttatggct cgtgtcaatt ctcttattcg tcggtatact atgttaaacc
    12001 ctgcttttat aacagacaca gattgcataa taataaatgg catgattatt gacaagacaa
    12061 accgaattgt ttctgtcaat aatattcctg ttcaacttac aagcaaagaa tttgatttac
    12121 ttgcttttct ggcttctaat aagggacggg tgtttaccaa aaaacagatt tatacacaag
    12181 tatgggaaga agaatatgct tttgacgata gtaacatcat gtctttcatc agtaaattga
    12241 gaaaaaagat tgaaccagac cccaaccatc cattttatat tttgacagtt cgtggtgtcg
    12301 gttatcgttt taataaggag gcttaacatg aatacaagtg tctatctgct tttgatattg
    12361 gttcttagcc tgattattat agcgtacctt gtttctgtcc tgctacgtgt ccgaatacaa
    12421 cttacactta taaaagatgc tttagaggat ataaaaaatg gaaaccttaa tcgacgtatt
    12481 ttaacagatg aaaacgacat tacaaaacaa atttgctatg atattaacga aatagcaatc
    12541 aatagccaat ttcaacttat tcagcaaaaa caatcagaac aagcctacaa acagctaatg
    12601 acaagtctct cccatgatgt aaaaactcca cttgcttctt tggtcggtta tttggaagca
    12661 gtagaaagta aaattgttgt aggagaggaa aaagacgagt atatccatgt tgcgtctaat
    12721 aaggctcatt acttaaagaa ttttgtagaa aatctatttg aatgggtaaa attggattct
    12781 aaggaacaag tttttcattt tgatattttt gacttgaatg aattatcccg taatattata
    12841 tctgattgga tacctgtttt agaaagcagt cattttgaat atgaatttga tataccagaa
    12901 atagagtact tcttacgtat agacgcaaat gcatataccc gtatcattaa taacctatta
    12961 caaaatatta ttacccatag tagtggcaac aaaatgacat tgagaatttt tgaaaacaaa
    13021 gagcaagctc aaattataat aacagataat gggaaaggta tatcttcaga caatctccca
    13081 catatttttg aaaggttgta ccaatgcgac cattcacgag cttcaaaggg aaatggttta
    13141 ggcttggcga ttgcaaagga acttattaac gctcataagg gaaatattac cgccaacagc
    13201 actcccggta tgggaacaga atttacaata ttgcttccta aagccctgta aaagtacgag
    13261 gctttcttac tctaaaacaa gataaaagca agattatggc aaggttttgg caaggttcat
    13321 gttttataat tctaattgta gttgattttg acgttgtatc aactatcttt tgtagaaaca
    13381 aatttattaa aagtgaggaa attatatatg aatgattttg tgattgaaac aaagcaactt
    13441 acaaaaattt atgggaatca aacagtagtt gacaaagtca atctccatgc aaaaaaaggc
    13501 cgaatatatg gtctgttagg acgcaacgga gctgggaaaa ccacaattat gaaaatgatt
    13561 ttaggattga cttcaatcac gtatggcgag gtagatgtat ttggagagaa tattaaggga
    13621 cgtgaaaaac aagtatatcc ccgtatcggt gcaattatcg aaacgccagg attttatcct
    13681 aatctgacag gaacggagaa cttggagatt tttgcaaaac tgcgtggtac agccgcccct
    13741 aattctgtaa aaagagcatt ggaaattgta ggcttacctt ataaaaataa aaagctgttt
    13801 agtgaatatt cacttggcat gaaacagcga cttggtattg ccaacgctat cctgcatgac
    13861 ccagaactgt tagttttaga tgagccaacc aatggtcttg accctattgg tattgcggag
    13921 atgagaaagt ttattaggga cttgagcgtt gagcatggaa agacaattct tatttccagt
    13981 catattcttt cagaaatctc attgttggct gatgatattg gaattatcga ccacggtgtt
    14041 cttttggaag aaagtagtat gagtgaacta gaaaagaaaa acagtaaata tatcctgcta
    14101 caagtttcag atattccgaa gacatcactt attttagagc gtcaatttaa cacgaaggat
    14161 tattccgttc aagatgacta cacgttacac ctttataaca ctaatctgga tatgggtgaa
    14221 atcaataaag cacttgtaat gcagaatgta actgttatta gttctcaact ttgtaatgat
    14281 actttagagg actactttaa aaaaatcaca ggaggagagg gcattgctta aacttattca
    14341 aacagaattt cttaaactgc gtcgtaggaa acttatttgg ctgatgttgt tgtctgctct
    14401 cattatgccg tttttcgcac tactatactt caattatttt ggtaaaacag gtgttgagcc
    14461 aataaagttt tataaatggt ctgcatttgg ttatacactt tggattattt tgcctgttgt
    14521 tttgggtata ttttgcacca tgcttataca cgaagaaaac cagtatgata tgctcaaaca
    14581 gctttggatt gtacctatta gtaaaatggg atactttttt agtaaatttt tcgttgtttt
    14641 gatttactct atttgtttta tgctgattac agccgttgct tctgtgttat ttagtgtact
    14701 ttctggatat gtcgtattta gctgggcaag cattttatat ttgttgaaaa aatgtttaga
    14761 aattggtgta atcactgctt ttgtaatgtt gccgattttg gcaatcgcta catctcaaaa
    14821 aggatacatt ctcccaattt gtatcacatt ggtatatgcc ttttccggtt ttgttataat
    14881 gacaataaat atgtatttac acccattatc cagtatggga gttattatca tgagaaataa
    14941 agacattcca ggtcttatat tttcacagga aattaatgtc ccattagcat ttctttgtat
    15001 ttgtatttgg agtattgtat cagtattgtt tgcaaacact gcactaggaa gaagaaagtg
    15061 aggtgtagat aatgtggaaa ttactttggg ctgaatgtca aaaaattcgt cgttcaaaaa
    15121 ttgtttggat tacagttttt gcatccatta tgatagcagt catagttttt gcaggagggc
    15181 aggatgtata taatgaccca gatttacatt atggcttaaa gagcgtttat gacggttcac
    15241 ggtatataga caatgcaggt tggtatatgg acgcagtaca accttggtca actttttttg
    15301 ttcttcctgc tgtcattgcc ctattaggaa gctatattat ttgtcgtgaa gaagaggagg
    15361 acactattaa atccctgcgt cttattccca taaatgaaac aaaattaacc atagcaaaaa
    15421 tgattattac ttttatattc agtatacttc tttatttgtt actctttact ataacatttt
    15481 tgactgaatc cgttttacat ttttccgatt tatcgacaaa actggtttta agttgcatga
    15541 aagagtattt tcttgatggc ataggtgtat tctttgcaat ttctcccatt attgccttgg
    15601 tatcgcgcat gaaaaaagga tattggcttg cattagtatt cacagaagtt tattctattg
    15661 ctggactatt tgcgggtatg tcaaatgtct tacaaacctt ttttcctatt gcggcaatat
    15721 ttaatatttc tggatactat ataactactg gagaaaaaat tatggggagt atcataagtt
    15781 tattactttg tgcctgcctt tctgcattta tacttaaagg gctaaaacac aatgaaaaaa
    15841 attgaaatag gtatatcaaa atgaaaaaga taaaaaaact gattattcta attgtattct
    15901 tgtttctttt tggcatgtta cactgttata ctgaatggaa attcaacaat aacccaccta
    15961 aaggggtaat agaaagaata aatgaatgga ctgataagat tggactggat tagtaactta
    16021 tgttaattat agtgaatgta atattagcaa gttattgttt cgtattttaa tactataact
    16081 ttaaatattt ggttttaatc ttccaaacga atataaaaaa actgtcacag aggcaacata
    16141 tttttgaata tttataaagt ggtagttttg attttcaaag ctgccgcctt ttcttctata
    16201 taagcaaact tatcctcaac aaagtgtaaa acatggtaca ttttaagaaa aaagtaccac
    16261 agacacaagc aataaaagaa acgccgagaa cctacaaaaa cgtagtgctt atgcagattt
    16321 acgacgcctt ctattttctc aaccgtctta atgaccttgt acaaaagaaa tttttctaat
    16381 attttttata atcttatctt gtgatgtttt ttatgtataa atgacttaat aacaaatcca
    16441 ataaaaatta tggatattgg tataattaga acgaggaatt tataatcatt ataatgtgac
    16501 attattctta cccaactctc agaaaaaata tatcctatac tgattaatga agtattccat
    16561 atggttattc ccacgataga tgatattaca aaagttataa tattttgacc tgctatacct
    16621 gctataaaag atatgtatgt tctacataaa gggattaatc tacatacaca aacagaaata
    16681 gaagagtatt tgttaaaata atcttgagat gcaaatattc ctttctttgc ctttggacat
    16741 atctctatta ttttatttat gatagattta cctccccaat ttcccactgt ataacaaaat
    16801 atcgaaccaa gtatacctgc aattatactt aaaattaaaa ttgtcagaaa tccaaaatga
    16861 tttcttgcag caattgctcc acataaaggt aaaacaactt cgctaggtaa tggaaaacaa
    16921 gcatactcaa tcataattaa tacaaataca gagattaatc catattgtaa aataaaacta
    16981 ttgattacag acacttactt atctatctcc tttcttattt aaaggtttta agggtacatg
    17041 ttctaaggat tctcacccta tatttaaaga atcaatctct ttaaactatt atatgtattt
    17101 acacaaagca tttataacat actttaaaaa tagtacctta aaataagaaa cttaataaat
    17161 aaaaaaagat tacgtggcta cgtcctactc tcccaggcag tttcccacca agtaccatca
    17221 gcgctagaga gcttaacttc tgtgttcgga atgggaacag gtgtatcctc tctgctattg
    17281 taaccacata atctttatgc ttaatatttc tattaagttt ttaataagtt tatagaacct
    17341 agtaatacta gtttctttag agttagcact ctaaaaacta cacatatatc ttaatgaatg
    17401 aacatcaaat
//
LOCUS       DAEHWO010000091        17318 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEHWO010000091 DAEHWO010000000
VERSION     DAEHWO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17318
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.091"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            262..1074
                     /locus_tag="KNP54_003319"
     CDS             262..1074
                     /locus_tag="KNP54_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBF0894180.1"
                     /translation="MYLERPELYKQSEINFWDDEYISEQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPVNYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            2123..2884
                     /locus_tag="KNP54_003320"
     CDS             2123..2884
                     /locus_tag="KNP54_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBF0894181.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            2949..3731
                     /locus_tag="KNP54_003321"
     CDS             2949..3731
                     /locus_tag="KNP54_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBF0894182.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKCKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            3998..4417
                     /locus_tag="KNP54_003322"
     CDS             3998..4417
                     /locus_tag="KNP54_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBF0894183.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(4520..4786)
                     /locus_tag="KNP54_003323"
     CDS             complement(4520..4786)
                     /locus_tag="KNP54_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBF0894184.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            5013..5714
                     /locus_tag="KNP54_003324"
     CDS             5013..5714
                     /locus_tag="KNP54_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894185.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            5796..6404
                     /locus_tag="KNP54_003325"
     CDS             5796..6404
                     /locus_tag="KNP54_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBF0894186.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            6728..7192
                     /locus_tag="KNP54_003326"
     CDS             6728..7192
                     /locus_tag="KNP54_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HBF0894187.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTYETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            7829..8845
                     /gene="gap"
                     /locus_tag="KNP54_003327"
     CDS             7829..8845
                     /gene="gap"
                     /locus_tag="KNP54_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBF0894188.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            9240..10409
                     /locus_tag="KNP54_003328"
     CDS             9240..10409
                     /locus_tag="KNP54_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894189.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYSPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            10789..15042
                     /locus_tag="KNP54_003329"
     CDS             10789..15042
                     /locus_tag="KNP54_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBF0894190.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            15191..15685
                     /locus_tag="KNP54_003330"
     CDS             15191..15685
                     /locus_tag="KNP54_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBF0894191.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            15801..16178
                     /locus_tag="KNP54_003331"
     CDS             15801..16178
                     /locus_tag="KNP54_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBF0894192.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            16384..16824
                     /locus_tag="KNP54_003332"
     CDS             16384..16824
                     /locus_tag="KNP54_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBF0894193.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
BASE COUNT         7061 a         1666 c         2996 g         5595 t
ORIGIN      
        1 tgaaaggatg atgttgttcg gtgatatttg atatcataaa atcgttgata taagtattgc
       61 tggaaaagag tgaataaaat caaatttaat aagcaaacaa agtaaagcta tagttttatt
      121 gttgtgctta aaaatatttg gttctatttt actcttattt aaactcatct ttttgaagtt
      181 aaaccacaga gtaaactctg tggttttttt attttaaaaa taaattttaa ggagtggtat
      241 gttttgttaa acaaattatg tatgtattta gaaagaccag agctttataa acaaagtgaa
      301 attaattttt gggatgatga gtatatttca gagcaattat taaaagcaca cttagacact
      361 aattttgaag gagcaagtag aaattttaac tttatcgagg attctgtaaa ttggatagtt
      421 acagttgcaa atccagttaa ttatcctaaa ttacttgatt taggttgtgg tccaggttta
      481 tatgcagaga aatttgcaca aaaaggttat aaggtaactg gaattgattt ctcaaaacgt
      541 tctattaact atgcacaaaa tagaaataag gagactaatt taaatataaa ttacttgttt
      601 caaagttatt taaatatgaa ctataatgag gaatttgatt tggctacctt aatttattgt
      661 gattatggag ctttgtcaac tgaaaataga aggttattaa tggaaaaaat ttatgatagt
      721 ttaaaacctg gaggaaaatt aatattagat gtatttacaa taaataaata caataatttt
      781 gaggaaatta aatattggga aataaatgaa gatggaggat tttggagtaa tgaaaaatat
      841 atgtgtctac aagataattg taaatacaat gattataata cattagaaca aactcttgta
      901 ataaccgaaa aagatgaaaa tgtattttat gtttggaatc actatttttc aaaagaaagt
      961 ttcttattag aagttgaaaa tattggattt aagtctgttg agttttttag taatgttaag
     1021 ggtgaagcat attctgacga tagtatgact atgggattag ttttacaaaa ataataattt
     1081 ttttaaaatg aataaataaa aacttgaaac ctttaacaat aaaataacat aagaaaagct
     1141 tacatattga aaaatggaaa cttttatgtt atttttagta cattacaaat ttgtttatat
     1201 aaaaatcaat acttgaatta ttatttttat gtgaaattta tctatagtat atttttataa
     1261 acaagtaatg ttattaaaat taagtatata gttaaaagtg tatagcaaaa aggctgttat
     1321 attaatgtta gaggttcagg gaaaatatat aaagcaaaga tatttacaga taatgtagat
     1381 tgcacagcta taagttagat aatagaatta tgtaatcaag aatttacaac aaagtataag
     1441 ataaggataa tgctaaattg ccatacaggt gctagatgtg taaatggatt taattaatac
     1501 tattgataaa gtgcaacaag cacataaacc aattgatgag attattgaaa ctataagaga
     1561 tatagttgac ataattaaaa tattggaacc tgtttataat tttaaatcaa atcaataatg
     1621 attaagatta aaataatatt aaggcatcaa tgttataaga gtacaatata aggagtacta
     1681 tatagtactc cttacttata catattaggc aatagggaat ttttttatag ttaaattttc
     1741 aaatattttt tagggaactt tataattgag aattaagggt atagtatgtg atgaacttac
     1801 taaatttata attaggttat ataatggaat aatcatcaat agttttactt tagggaaaat
     1861 atatgcttaa ggaagtatag cttactaata ttattaaaat gtatatttaa aatgataaaa
     1921 aaagaattag acaagtattt agtaaattga ctatgcaaaa ttctatcaag caggaacact
     1981 atgactttag tcatgggagg ttcagtaggt aacttgttga attaagttta tattatttaa
     2041 ataaactact taatttagat aatataaaaa gtcagaattt taagaataga gctatataat
     2101 cttagctatt aggagaagta ctatgatagg aatatatttt agtggaacag gaaattcaag
     2161 atactgtgta gaaaaatttt tacaagaata tgatataaca gcaaattctt attctattga
     2221 agataatgaa cttttacagc acatcaataa tcatgagaat attattttta gttatcctgt
     2281 gcaatatagt aatgtgccaa aaatattgaa agattttata ataaatcatt caactttgtg
     2341 gaatggtaaa cgtgttttta ttattgcaac tatggctcta tttagtggag atggctctgg
     2401 tgtgttagct agaatattaa aaaaatacgg tgctataact gttggtggat tacatgtgaa
     2461 gatgccagat agtataggag atgaaaaggt attaaaacat tctttagagt ataatagaaa
     2521 gcttgtaata aaagcagaaa agaaagtaac taaagctgct aaaaaactga aacatgggtc
     2581 accaccaaaa gaagggttgg gttttttgag tcatattgta gggttatttg gacaacgatt
     2641 gtattttatc aataaaacaa atatgtatac agataaacta aaaattaata ctgaggaatg
     2701 tattgtatgt ggtaaatgcg ttaatttatg tccaatgaag aatctagtaa ttaaaaattg
     2761 tatgattgtt gcaaatgggc aatgtacaat gtgttatcgt tgtgtaaata attgtgccaa
     2821 aaaagcaatt acattgttag gtaaaaaagt tgttgaacag agtaatatta aaaaatatat
     2881 gtaagaaatt taaagtttta ttgaatgtaa attgatgtat attttatgtt agaaagagag
     2941 gttaaataat ggaatactac atagttgatt catttgcaac taaactattt aaaggaaatc
     3001 ctgctggagt ttgtgttctt gacagaagaa tacctttaga gttaatgcag aaaatagcag
     3061 aagaaaacaa tttaccagaa acagcatttg tagttaaatg taaaggaaat tatgaattac
     3121 gatggtttac tcctaaagca gaaattgatt tatgtggtca tgcaacttta gcagcagctt
     3181 atgtaatatc aaattttatt gatgttaatg taaaaaggat agatttcttt actcaaagtg
     3241 gaaagcttga agttacacga aatggaaatc tatatgaaat gatatttcca gaaataatgc
     3301 ctattgaaat agagttatca ccacaacaag ctaatttgat aggctgtgta ccaagtgctg
     3361 tttattcttc aagagattta atcttattgc taaacagtga acaagaagtt ataaattata
     3421 aacctaatta cgcacaattg cgtaaattga cagactggtt aggtataata atcacagcac
     3481 aaggaagtaa tacagatttt gtatcaagat atttttgtcc agaattagat tcagaagacc
     3541 ctgttactgg ttcatcacat tgtaatctta ttccatactg gtctgaaaag ttgggaaaac
     3601 acaaaatggt agctgctcaa ctttctaatc gtggtggtat aattcagtgt gaagtgttga
     3661 aggataatac tgtaaaaatt tctggtgaag cagtcttgtt tatgcaggga acaataaaga
     3721 ttgatattta aataagtata ataactaatt tattatgaaa aataattaat tttcttagtg
     3781 ttaacaataa taaagtagag ttaaaaagct tgatttcact taaatcaata tgatagatgt
     3841 tgatactaag attgacaagc atgattaaaa aagataatat ttaatctata aagataaaaa
     3901 cacagtctgg ttggtagtcc agacgcagca atagctgtca gtaacctgcc tccttggttg
     3961 tccgttcttt agaaagtaat ttaaggagga actagcaatg gacaaaatta gtggaaaatt
     4021 aacagtttta tttgaagaac cattttgggt aggtatattt gaaagacaag atggtaaaaa
     4081 atatgaagca tgtagggtag tttttggagc agaacctaaa gaagtagaag tgtatgaatt
     4141 tatacttgaa agatttttct cattagattt tggtagcatt aaattagaaa aaaatgtgac
     4201 caaagacaac attggataca aaagaatgca gagaaaagta aaaaaggaac aagaaaaaga
     4261 aactataggg actaaggctc aaaatgctct taagcttcaa tatgaagaaa gaaaacagga
     4321 tagaaaaaac ctagctaaaa atagaaaaga agaagaaaaa gaaagactat ttaatttgaa
     4381 acaagaaaag agaaaagcta aacataaggg tcattaattt taattaaata tctttttaat
     4441 aattgctaga aaaaggtgta taaaattttt aattttatac accttaattt attgaaaaga
     4501 ataaggtttt atatttcaat tactttaaaa tataaaaata tactaataaa aattgtaaaa
     4561 atagtataaa tggtatacca aatgtaaatt taatgtgttt agttttatgt ctaaaagaat
     4621 acattccaat tatagaacct atactacctc caattactgc tatagacata agagtagctt
     4681 cttttattct ccattcgttt ctaattgctc ttttcttatc tatgtacatt gaaaagaaag
     4741 caatagaatt aatcactata aaatatatta gaataaaatt tttcacagtc ttgcctccat
     4801 aaaaatatat tatacattat aaaacaagat atttgttttg gaaagttaaa tttgtaatta
     4861 gtacatataa aatatttgat aagaacaaat ataatattaa ttggaaaatt taaaaaaatt
     4921 aaacaattag caaatagggg gtatatttat aagacacaaa gtgataaaat ctatttagaa
     4981 aataatgtaa aataacagga ggataaagca aaatgaaatt tatagtagaa aaagaagttt
     5041 ttgataaatt agaaaatgta tgctttggtg tagtagttgc aaaaggaata gataatacta
     5101 aagaaataga aagaataagc aaccttttag atataagtat agatagagta gaagattact
     5161 tcaaagataa aaaagtaaag gaatcagaag aaattatacc atatagagag gcatttagaa
     5221 gtctaggcat gaacccaaat aaatttatga gttcgataga agcaatgaca acaagggttg
     5281 ctaagaataa gaaacttcct catataaatc ctattgtaga tttaggaaac tctatttctt
     5341 taaaatattt acttccaatg ggtgctcatg atatggattt tagaaatgat gatgtatatg
     5401 ttagattttc taaaaaaggg gataaatttg taccatttgg agaaactgat gttgaattaa
     5461 tggaagaagg agaattaatt tattcagttg gagacatggt aaaaactaga agatggatat
     5521 ggagacaagg agaggaagga aaaattacta atagctcaaa aaatatattt tttcctatag
     5581 atggttttac tgatgctaat ttagataagg taatgagtgc aagagaagaa ttagcaaaat
     5641 tgttaaagga aatatttaat tgtgaaatta aagtaggttt tgtagataaa gataatcctg
     5701 aaatggaaat ataataagtt gttgaatact tgttaagata ttatatttac ttaatgatgt
     5761 taaaaaggta ttaaaaaaga aaggtcgtag taaatttgaa aaaaactata ataaagaatg
     5821 taaatccaat gattgaaaat aagtttatag gactttttga aatagagtat aaaaacaaat
     5881 tagatgaaga taaggtttgg atggtagcat caagaaaaag tagtgagcaa ttaaaaaata
     5941 tttatttgaa gaatgaagaa gatagtgtag atgcagttgt aatagttggg cttcataaaa
     6001 gtagtaaaaa attaatttta ataagacaat ttagagtacc tattaatgga tatatatacg
     6061 agttaccagc aggtcttgtt gatgaaggag agtctataga tatttccgtt gaaagagaac
     6121 ttagagaaga aacaggactt actcttttag aaattaaaaa aaataaaagt attgataaag
     6181 tttatttatc tcctggaatg agtgatgaat ctgttgcctt tgtttattgt atatgtgatg
     6241 gtgatataac agatgaattt ttagaaccag atgaagagat tgaagcgctt ttaatttcgc
     6301 aagaagatgc aaaagagatt ttacaaagta atcataagat agacacaaaa gcatttttga
     6361 ttttacaaat gtttgtgagt ttaggagcta aattatttga atagatatat agaaaagagg
     6421 ttatatagaa gagtaaaata ataaagttta ttttacttgt ataaattata atctcttttt
     6481 ttatacaata aagtataatt ttgtgtattt ttaaataagt gacttgactc ttaaattttc
     6541 ataatatgtt ataaaccaat ttaagatact acaataatta aaattccaaa attatttaac
     6601 atatttgcaa ttaaaatgag aaaaggtaaa ggttgaatga ttgaaaaatt tgatgtaaaa
     6661 tagtagctta gtttaatatt atagtttgta gggttaaaaa ttagaaattg taagggagat
     6721 aaattctatg aaaaaattag ttattatttt aattagtatc attagtatgg ttagcttgac
     6781 agcttgtaaa aaaagcaatg aaagtaaata taataattta aacaacaaag aatccggaca
     6841 aacaaccatt gaaatggact tagataaaaa ttatgatact tcagacccat ttgttaatgc
     6901 acgtttgttt tgtgtgtcta atgatataga tgttttagac acagagattt cttttaaaat
     6961 ggatggagat agtggtattg tggaaataaa ggacaataaa acatatgaaa ctttatggag
     7021 taatacatgg catggaagcg ttgataatga tacattcaca atttctcttt ctaatataca
     7081 aaaagagaaa gagtatgcta tatgctttac tggaattaaa ataaatcatg cagttgtaaa
     7141 ggttactttt gaaagcaatt tagttaagga gaaagaaaaa ccctcaaaat aaattccaga
     7201 ttgtctataa cttgatattc agtacataaa agcagttgat atttatgatt gactgctttt
     7261 tcttatcaaa aaggagagtt tgtgcatttt tacttgaaat agtttatgca catcaaaagt
     7321 tggtgagcat gatattggaa atggtaagca tgaaatcttg ataagacaag gaaataaatt
     7381 taagttttca attaagtata tttccataat ttagttaaca ataagctaat tattatttat
     7441 attttgatat ataaataata attgtagcaa atttcaaaaa atcatatatt ttttgaacta
     7501 aataaaaatt tatttttatt attttaaatt agaggagatt cttgaagata tattattttt
     7561 aaaaataagt atagtttaaa aattcaaaaa aaagatggca aaatatgtcc caagggacat
     7621 tgagtaaaat aaatgatttc agcttattta cactaaaaag tacatactaa atgaggggta
     7681 aaataaagaa aaatgatata ctaattgtct tttgataata aaaaaacatg gaatttgatt
     7741 atttaatcaa gaaaaagtat tgaacaaatg atttatttag tgtacaataa tcatgtaaaa
     7801 acatagtaat ggagggagac atttcataat gaaaattaag gtaggaatga acggatttgg
     7861 aagaatagga agagctgtat taagaatagc tcaagaagaa ttaggagata atatagaaat
     7921 tgtagccata aatgcaagag caacaacaga atctttggca catttattta catatgattc
     7981 atgctatgga acttttagag gtgaagtaga ggcaaaggat gaagacactc tagtagtaaa
     8041 ctctaaagag ataaaaatat taagatataa tgacccagaa gaattaccat ggaaagaact
     8101 gggggttgat atagtaatag aatcaacagg attatttaca caaagagaaa aggcagaaaa
     8161 gcatattaaa gcaggagcaa aaaaagtaat tataacagct ccaggaaaaa atgaagatat
     8221 aactatagtt atcggagtta atgagaaaga atatgataat gaaaagcaca atataatttc
     8281 aaatgcatct tgtactacaa attgtctagc tccttttgct aaagtattgg acgaaaaatt
     8341 tggtatagta aaagggttaa tgactacagt acattcatat actaacgatc aaagaatatt
     8401 agataaaagc cataaagatt tgagaagagc aagagcagcg gctgaatcta taatacctac
     8461 cactacagga gcagcaaaag ctgtgtcaag agtactacca caattagaag gaaaattaaa
     8521 tggtttttca cttagagtac caacaccaac agtttcactt gttgatttag tgtgcgaact
     8581 taaagaaaac gttacatctg agcaagttaa ctctgtgtta aaagatgctg ctgaaggaga
     8641 attaaaaggt gttttaggat attgtgacaa gccacttgtt tctatagatt ataaaggaga
     8701 ttcaagatca tctattatag acgctctatc cacaatggtt atagaagaca atatggttaa
     8761 ggtagtttct tggtatgata atgaatgggg atattcttca agaactgttg acttagtaaa
     8821 atatgtagct gaaaaattaa aataatatat atttcttaaa gcaaatttta aaaaaatttt
     8881 ttaaaaaaat tatataaaac taaaaaaaaa gattatgaaa aatattgaag gaaaaatttt
     8941 ttcataatct tttttctttc atgcaaaaag atacaagtta caacttatat ttgcatatta
     9001 ggtcgttaga gaagtatata tatatttagt aaggaatcat actttttata aaatgaaaga
     9061 taagatgtcg aaaacttgca taaatctgaa aaatttttat tattaaaata ctgatttcca
     9121 ttttaaaaat gataaaaaaa tgacaaataa agttgcaaat agtaatactt ataagtataa
     9181 ttaaaaaaga gaaaaggttt tgttaaactt tataacaaaa aaagaaggga tgattcaaaa
     9241 tggagaagtt aacagacagg agacaggtta aggcagtaag catggaaacc ttcattttcc
     9301 taatattact agtagttggt tttgggtatg ttggtagtat tatgggagca ggaatgatgt
     9361 tcaaagtaat aatgagtaca gcacatgctt tactattgga gacagttttc ttaattatgg
     9421 ctatggcagt tcttgcaggc gcattaagcg cactactttc agagtttgga gtaatagcgt
     9481 taattaataa aattttcgct gtatttatga agcctttata tggactacct ggtgctagta
     9541 tagcaggagc tataacaact tatttatcag ataatccagc tattatacct tttgctaaag
     9601 ataaaacatt cacacagtat tttaaacaat accaagttcc agcattatgt aacttaggaa
     9661 cagcctttgg tatgggactt atcttaacaa catttatgat ttctcaaggt acagaatatg
     9721 tacttccagc attaattggt aatttaggtg caattatagg tagtgtcata agtgttagaa
     9781 taatgttgac atttactaag aagttttata aatacagtcc ggaagaagat aaagcaacag
     9841 gaacattaga gaaaaaggat gaatttagag aaatcagaga aggaaatgta tttcaaagag
     9901 ctttagatgc aattcttgaa ggtggtaaaa tgggggtaga tatgggaatg gctataattc
     9961 ctggagtcct agtagtatgt acattggtga tgttattaac ttttggacca tctacagacc
    10021 ctgttacagg tcaagaagtt tatacaggag ctgcatatga aggaataaaa ttacttccag
    10081 ttattggaga taaacttgga tttatattag aaccattatt tggatttaca tcaccagagg
    10141 caatagcatt ccctataact tcattgggag ctgttggcgc agcaatgtct ctagttccag
    10201 agtttataaa gtcaggagct ataactccta atgatatagc agtatttaca gctatgggta
    10261 tgtgttggag tggatattta agtacacata ttggtatgat ggatgcatta aatgctagac
    10321 agttggcagg taaagctatt ctttctcata caataggtgg tttatgtgca ggagcagctg
    10381 ctcactttat atttacactc gtaggataaa tgtaatcagc taagataaaa aataatatac
    10441 aaaaaatggt tgttgatatg taataagaat ttacatatca acaaccattt ttttctgact
    10501 aaagataatt tataatacat aaacattaag tggatattag agttaagtta tatttatgta
    10561 aaaagtaaca aaaatctgta gaaatttatg acaaaattta gtacactaac tatatgttct
    10621 tatttaaaat ttaaggttag aattaggaat tacctagtag agtaagcttt gattaataaa
    10681 agaatcataa aataaaaata ttagtcataa agattataaa taacttactt aaaataaagc
    10741 catagaactt acaaaaatta aaaaagcata taaatatgga ggggtacaat ggatgaatta
    10801 tttcatatag gaattgatgt aggttctaca acggtgaagg ttgtggtact taataatagt
    10861 aataatatag ttcataaaga atatagaaga cattattctg atgtaaaaaa atcagttaaa
    10921 gaagtactaa atggtatata tgaaaaattg ggagatataa atactaccat tataataact
    10981 ggttcaggtg gaattggaat atcaaaaaaa ttaggtgtaa aatttgttca ggaagttata
    11041 tctagtacaa aatcaataga gtattttcat cctgagactg atgttgtcat agaacttggg
    11101 ggtgaagatg caaagataac atatctaagt ggaggaatag accaaagaat gaatggaata
    11161 tgtgcaggtg gcactggagc attcatagac cagatggcat cactcttaaa gacagatgcc
    11221 agtggattaa atgaacttgc taaagggtat aatgttatat atcccatagc ttcaagatgt
    11281 ggtgtttttg ctaaaacaga tattcaacct cttataaatg atggagccaa tcagactgat
    11341 atagcaatga gtattttcaa tgcagttgtc gtacaaactg tgagtgtcct ttcttgtgga
    11401 agaaaaatag aaggaaatgt tgcgtttttg ggtggtccat tgtacttttt atctgaactt
    11461 agagaagcat ttaaaagagt attagattta aaagatgaaa acataatctt cccagaaaat
    11521 gcacaacttt atattgctat tggagcagga ttattatcag tagatgaaga taatatacaa
    11581 ctaaaatctc taatagaaaa attggatagt ataaagaata ttgaagatgg agaagtaaat
    11641 ttattagaac ctttatttaa agataaaaat gagtatgaag aattttcaag aagacatgaa
    11701 aaagaaaaaa taaattatgt ggacataaat tcaataaaaa gcaattgtta tttaggaatt
    11761 gatgcaggct caactacaac taaagcagca cttattgatg aggatggaag acttgtatat
    11821 tcttattata atagcaatga aggaaatcca ttaaaaacaa ccattaaagt tataaatgaa
    11881 gtatatgata tattaccaaa aaatattaaa atattgagtt caactgtaac tggatatgga
    11941 gaaggtctta ttaaaaaagc tcttaaaatc gataatggag agatagagac tatagcacat
    12001 tacaaagctg ctaaattttt caacaaagat gtagatttta tacttgatat tggtggtcaa
    12061 gatatgaagt gcctaaaaat aaaagatgga gtaattgata atataatatt aaatgaggct
    12121 tgttcatcag gttgtggctc atttttagag acatttgcaa gttctttatc tatgacaata
    12181 gaagaatttg cgcatgaagg tatttattct caaaatcctg tagatttagg ttcaagatgt
    12241 actgtattta tgaattctag agtaaaacaa gctcaaaaag aaggtgcaag tgttggagat
    12301 atatcagcag ggctatctta ttcagtaata aaaaatgctt tatttaaagt aataaagatt
    12361 agagatttaa atgagattgg taataatatt gttgtacaag gtggaacctt ttataatgat
    12421 ttggtgctta gaagctttga aaaactaatt ggaaaaaatg taattagacc taatatttca
    12481 ggaattatgg gagcttttgg ttcagcactt atagctaaag aaaaatatga aagtggatac
    12541 aaaacatcct tgttatctaa ggaagagttg aataatatca agctagaagc aagtgtaact
    12601 agatgtaaag gttgttcaaa tcattgtctt cttacaataa ataaattttc tgataatgaa
    12661 atttttattt caggtaatag atgtgagaag ggtgaagcta tttatggtga taaaaaaata
    12721 ggattagaaa agaaaaaacc aataaattta tttaagtaca aatacaatag aatttttaga
    12781 tacaaaccat tggaaaaaga agaagcaaaa aatggggaaa tagggatacc aagagtatta
    12841 aatatgtatg aagattatcc attttggttt acttttttca atgctatggg ctttagagtt
    12901 gtactttcag ataggtcatc aaaacagtta tatgaaactg gtataactag tattgcatct
    12961 gaaacagttt gttatccagg aaaattagtt catggacata tagaaaattt aattgcaaaa
    13021 ggtataaaaa atatatttta tccaagtgta acaaatgaaa ataaagagga ttcaaatgca
    13081 gataattatt ataattgtcc tgttgtaata tcatattctg aagtaataaa aaacaatgta
    13141 gagaatataa gaaataagaa cataaattat ataaatccat ttataagtct aaatgataag
    13201 gaaaaattga agaaaagact ctatgatgaa ttatcaagac atttttctga tataaaaata
    13261 actaaagaag aagttaatca tgcagttgat aaagctactg atgaacagaa tttatttaaa
    13321 atggagatac aagcagcagg tgaaagagca cttaaagaaa taaaagaaag aaatatgaag
    13381 gggattgtgt tatgtggaag accatatcat atagacccag aaataaatca tggaatgcca
    13441 gagcttataa attcattaga tatggcagtg cttactgaag actctatatg tcatttagcc
    13501 aatgtacaaa gaccacttag agttgtagac caatgggtat atcattcaag attgtataaa
    13561 gcagctagtt ttgtaagaga taaaaactat ttggaacttg ttcaacttaa ttcatttggc
    13621 tgtggattag atgcagtaac tacagaccag gttcaagaaa tacttaatga aaaatcgaag
    13681 atatatacta ttataaagat tgacgaaggc aacaatttag gagcagctaa gataaggatg
    13741 aggtccttaa aagcagctat gtttgagaga gaaagcaaaa atatagatgt aaaaaatata
    13801 aaggtaaaca ggatacagta tgctaaaaat aatcagataa cgaacaaaca tactatatta
    13861 gcaccacaaa tgtctccaat acatttccaa ttccttgaaa aagctgttaa cttaagtggt
    13921 tataatatag aaattctaaa agatactgat agtagtgtaa ttgaagaagg gttaagatat
    13981 gtaaataatg atgcatgtta tccagctata atagttgtag gtcagctaat aacagcatta
    14041 aaatctggca aatatgattt aaataacact tctgttacta taactcagac tggtggaggt
    14101 tgtagagcta caaattatat tggattctta agaaaggcta tatacgatgc tggatttaaa
    14161 gatgttcctg tcattgcact tagtgtaaat ggaatagaag atagtggtat aatggataat
    14221 atatcactaa aattaatcaa tagactcttt atgtctgttg tttatggtga tttgctgatg
    14281 aaagtactat atagagttag accatatgaa aaagttactg gaagtgcaaa tgctctatat
    14341 gaaaaatggg ttgatatatg caaatcttct cttgttaaag caaaaatttc tgtatttact
    14401 agaaatataa aagatatagt aaaagaattt gataatttag agatactaga tatcaaaaaa
    14461 ccaaaagtag gtttggttgg agaaatattg gtgaaattcc atccaattgc aaataataat
    14521 ttagtagata tattagagcg agaaggtgct gaagcagtcg tgccagacct tacaaatttc
    14581 ttcttaagtt gtgcctttaa tactatatac aaacacactc atttagaagg aagtagaaag
    14641 agtagaatga taggagaggc atttatatac ataactggaa tatatcaaag agtatataaa
    14701 aaagcacttg ataagagtga gagattttat gctccagcca atataaaaaa tgttgctaaa
    14761 agtacagaac cagtagtgtc attaggtaat caaactggag aaggttggct tttaacaggt
    14821 gaaatggttg aattattaaa tgaaggtgta gaaaacatta tttgtatgca accttttgga
    14881 tgtttaccta atcacataat tggtaagggt tctataaaag aattaaagag gttgtataaa
    14941 aatgcaaata taatacctat tgattatgac ccttctgcaa gtgaggtaaa tcaacttaac
    15001 aggataaaac ttatgctttc taaggctttt aaaaatatat aagatttata ttttgatatg
    15061 ttaaaagtta atgaatttaa aaatatactc tatattaagt atctataaaa aagagttatc
    15121 ctatttttta gggtaactct ttattagtta aaaaattata tgtatactga tattaaaggg
    15181 gggaagtaat atgagtttag tatatgatgt ttataaatca aaattaggaa atttgtacat
    15241 attaagtgaa gatggtttta tagttagtat atacatagga gatgaaaaat ttaataattt
    15301 aaaaaatgaa tgtattaaaa aaggaattga tataaagaga agtaaggaag atttaaagga
    15361 agcaataagc cagatagatg attactttaa tggaaaaaga aaagtcttta atttaaatat
    15421 tcgtattgaa gggactgaat ttcaaaaatc agtttatagg gaaatgttaa aaatacctta
    15481 tggagaaaca ttgtgttatt cagatatagc aagaaatata aacaatccaa aatcagtaag
    15541 agcaatagga caagcaagta aaagtaataa aattccaata ataatacctt gtcatagagt
    15601 agttggcaaa aaagatattg gtggatatat ggggaatcat tctgatttga aagagatact
    15661 attaaattta gaaagacaga gttaacttag aaagaaatgt ttttattgtt aatatttgat
    15721 ataataatag taaaaagaag tattttttac aaaaacaatg aagaatttat tttaatttac
    15781 aaaaatgagg gggaatttta atgtgtgata aagttatagc atcaaaatat catgagaagg
    15841 gatttaattg tgcagaatca gttataaaag catataatga ggaatttaat acagatatac
    15901 cagtttgttt aggaagtgga ctgggttcag ggtgtggggt tgctagttta tgtggtgcag
    15961 taaatgcatc aaatataata attggatatg taaaaggcag aaaccacgaa gatgaaagta
    16021 ctaaagctaa agtatatgct aaagatttaa ctacaacagt aagaaaagag tatggttcag
    16081 agttatgtat agacctaaaa aaagatttag ttgcttgtag agaaataatg gatttcgcat
    16141 atgatagtct aaaggaaact ttaaaaaaag aattataaga aaataagcta tcaaatataa
    16201 attatttgat agcttatttt tatagccgat actaaataaa tcaaatatat tttagaatta
    16261 ttatttgtaa ataaacagca aataatttta ggctttttat ttaatatagt ttttatttat
    16321 atttattttt gaatatgtta tactttgttt aaataaatat ttgtaatgag ggagatgaga
    16381 agattgaaga atctcaattt acttattaat aaattatatt caaaaaatca taatgaagca
    16441 tataaaactt ttttattctt agaaaatgaa agtttaaaat caaatattac atattgtttt
    16501 tttgactcat tcctagaaat gattgataac gaaaactcat atattcgaac aaggggattg
    16561 ttattaatct ctgcaaatgc tcagtgggat attgataata aaattgaaat aaatatagat
    16621 agtatactaa gtcatatcgt agataaaaaa ccttctgtat caagaatgtt tattaaatcc
    16681 atacctaata ttacaaagta taaagaaaat cttattaatc gcataaaaat ggaattaagt
    16741 aatgcagata taagtattta taataataat atgaaaccat tagtagaaaa ggatataaac
    16801 gatacattat ctaatattag ttaaatatta atatagaaat tgaatattat ctagttacaa
    16861 ttatttataa ctaagataat aaaacaacaa tggtgctaat ttatatgtat aaattaatta
    16921 tgaaaaattt atataagtaa aatatattaa cataaaggta aaattttgta tactaaaagg
    16981 gaatatttac agtttaatgg cagttttaaa ataataaatt aaagctgtca tttttattta
    17041 aaaattttta gaaaaagtac aatagtgtta atgtgtgaat tagataaggt gtatataata
    17101 gtttagatga tatgatataa aatatgttgt aaattaaatg ttttctttga caatatatac
    17161 acaaggatga taatatctat atgaataaaa gatagtgtgt aatttgataa tatgtaatta
    17221 taacattatg atataattac aataaagtat gtaataatct gtagaaattt caagctagtt
    17281 atctaagttt tcggataact aaatctaaac ggaataca
//
LOCUS       DAEHWO010000092        17114 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEHWO010000092 DAEHWO010000000
VERSION     DAEHWO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17114
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.092"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            110..739
                     /locus_tag="KNP54_003333"
     CDS             110..739
                     /locus_tag="KNP54_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894194.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            740..1522
                     /locus_tag="KNP54_003334"
     CDS             740..1522
                     /locus_tag="KNP54_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894195.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1515..2393
                     /locus_tag="KNP54_003335"
     CDS             1515..2393
                     /locus_tag="KNP54_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894196.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            2426..3385
                     /locus_tag="KNP54_003336"
     CDS             2426..3385
                     /locus_tag="KNP54_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBF0894197.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFYEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3700..4392
                     /locus_tag="KNP54_003337"
     CDS             3700..4392
                     /locus_tag="KNP54_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894198.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4402..5406
                     /locus_tag="KNP54_003338"
     CDS             4402..5406
                     /locus_tag="KNP54_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0894199.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            5674..6525
                     /locus_tag="KNP54_003339"
     CDS             5674..6525
                     /locus_tag="KNP54_003339"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBF0894200.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6629..7375
                     /locus_tag="KNP54_003340"
     CDS             6629..7375
                     /locus_tag="KNP54_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894201.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALLRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7375..9291
                     /locus_tag="KNP54_003341"
     CDS             7375..9291
                     /locus_tag="KNP54_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894202.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVIMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKSISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFFIVR
                     NNYLKEIRLNLVNF"
     gene            9571..9804
                     /locus_tag="KNP54_003342"
     CDS             9571..9804
                     /locus_tag="KNP54_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBF0894203.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSIFISTKW"
     gene            10000..10428
                     /locus_tag="KNP54_003343"
     CDS             10000..10428
                     /locus_tag="KNP54_003343"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBF0894204.1"
                     /translation="MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKNFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(10882..11652)
                     /locus_tag="KNP54_003344"
     CDS             complement(10882..11652)
                     /locus_tag="KNP54_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894205.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLSL
                     NKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTFYCCGNCDSEISLSQREHFKI"
     gene            11976..12521
                     /locus_tag="KNP54_003345"
     CDS             11976..12521
                     /locus_tag="KNP54_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBF0894206.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            12553..13689
                     /locus_tag="KNP54_003346"
     CDS             12553..13689
                     /locus_tag="KNP54_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBF0894207.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            13693..15084
                     /locus_tag="KNP54_003347"
     CDS             13693..15084
                     /locus_tag="KNP54_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBF0894208.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIINIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            15160..16035
                     /gene="dpsA"
                     /locus_tag="KNP54_003348"
     CDS             15160..16035
                     /gene="dpsA"
                     /locus_tag="KNP54_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBF0894209.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            16038..16628
                     /locus_tag="KNP54_003349"
     CDS             16038..16628
                     /locus_tag="KNP54_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBF0894210.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(16835..17035)
                     /locus_tag="KNP54_003350"
     CDS             complement(16835..17035)
                     /locus_tag="KNP54_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894211.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT         6674 a         1757 c         2826 g         5857 t
ORIGIN      
        1 tagataaaaa ttgttttatt aagaaaaaat taatatattg acaaaattta agtgctcatt
       61 taaactatta attgataata atattcaata ttaaataata ggaggcgtta tgaataaata
      121 tcttctaata aatccagtgg cagaaagaat gtatggagaa aagtttcacc ttattaaagc
      181 aaatttgata aaaaaggggt acataatagc agaatgtgaa ccacagttag aatatgtaaa
      241 aaagcagtac aaagagtata caaaaaagac tgaaaataca atgttggatt gtagatgtcc
      301 agaaagtata agtcttttaa aaagaaataa tttgataaat gattttgaag tacctatgat
      361 agaaccaata ttagtaagga cttgtagggt tttatacgat aaatatataa aaagtaaaga
      421 tgatatgttg gtagtaacct gtccatgtac acaattaaga gactttgcaa gtgaaaagtt
      481 taaggataag ggtaatgcta tgttttatac atggaaagag tttgctgaac aagaaggtgt
      541 aaaatcactt ggaaaaatag atgaatcacc aattccatta ggatatttca aagatacttt
      601 tgaaaaagtt cttgaagtat caagtgaaga cgaaatatta agtgaaatac aaaaaataag
      661 aaatggcttt gaagataagt atgacatagt agaaatgttt tattgtaaag atggttgtaa
      721 taatggagat ggtttgtaaa tggtcaataa atttaataat aagtttttaa ggctagtaaa
      781 gagtgttttg atatttttta taattctttt attatggaaa attacaaatt atcttggtat
      841 ttggagtgat tatatattac catcacctga aaaggtatat agtacatttt taaatatgat
      901 aagtgatggt tcaatattta ttaatgtata tgcaagtatg aaaagagttt tgataggttt
      961 tgcaataagt actgctatag gtgtgccttt agggatattc tttggaattt atagtggagt
     1021 atacgaatac tttaaatctc taataaattt tttaaggaat acacctcccc ttgctttaat
     1081 accaatgctt atattatggt ttggtatagg agaggaatca aaaattataa ttatagtttt
     1141 agcatccttt ttcccaatct ttacaagcac attgaaaggg attaaaaatt gtgactcaaa
     1201 actgattgaa gtgggtagag tatttgagtt ttcaaagctt cagataatat ttaaaataat
     1261 aataccaaat gccattcttg atattgctgt tgggttaaag ttagctcttg gatatagctt
     1321 tagagccatt attggggcag aacttgtagc agcttcatct ggtcttggat acttgatatc
     1381 tgatggaaaa gaaatgtcta gaacagatgt tgttattgta ggtataatcg taattggact
     1441 tttaggaata attacagatt acatattttc gattattgtg aagaaggtaa gtaagggaaa
     1501 gatggtggaa gcatatgaat aatttagtat gtgactctgg atatataatt agaaatttat
     1561 ataaaagtta taaagttgac aatgaagaac atgtagttct tagtgatatc tctttaaaca
     1621 tagatagaaa ccatataaca gtaattttag gtgaaagtgg ttgtggaaag actaccttgc
     1681 ttagagcaat tgcatcactt gaaggtataa atagtggtga aattaggttt attaatgata
     1741 ataaagagta tagacctaat gttggttttg tttttcagga gagcagatta atgccttggt
     1801 taaacgtaag tgaaaatata gcttttcata atcaaagaaa aaatactatt ttaaacaagg
     1861 tgcttagaaa atttaaacac aataaaagaa ttagcagtaa aattataaat gataatttta
     1921 gaagcttaga aacaaatgat aatttgaaca aatcaaataa atataatagg aaaagtaata
     1981 ttgatgtaga aaaatatctt aagatgatga acttgcagaa atttaaaaac tcttatccaa
     2041 atgaattgtc aggaggtatg gcgcagagag taagcatagc tagagctctt tctttcaatc
     2101 cagatatgtt gcttatggac gagccttttt cggcattaga ttattttaca aggattgata
     2161 tgcaaaatga agttataaga atacataagt caactaataa aggcgtgata tttgtaactc
     2221 atgatattga tgaagcgtta aagataggca agaaaatagt tgttttcaca gacgaaagaa
     2281 aagtaaaaga atttaatata gaagatggtt ataatagaga tttaacttca gattactata
     2341 ttaaattaaa aaaagatatt ttaatgacaa tgaaatcaaa taaaggcatt taaagaaatt
     2401 aataatattt taaggagtaa agtaaatgaa attaaaaaag ctattgatag gtataacaat
     2461 attaacactt gcaacagcat ctttagctgg atgtgctaaa aaaaataatg gagaaaaact
     2521 ttcagaaata aatttaactt atgtaaaatc accattaaat gttccttcta taattcaaaa
     2581 acaggatgat ttatttggaa aggaatttaa aaaggataat ataaaagtta atttctacga
     2641 aattactaca ggtccagagc aaacacaagc tttagctgct ggagaaatag acttcttaca
     2701 tgcactaggt ggtacatcag ctttaatagc tgcatctaat ggagtagagt taaagatatt
     2761 aaacacttat agcaggtcac caaaaggatt tatgattttg actaataata attcaataaa
     2821 atcagcagca gatttagtag gtaagaaggt ggcaggccca aaagggacta tattacatca
     2881 ggtattgatt tcagcacttg ataaagaagg attaagtatg gatgatgtgg aatttgttaa
     2941 tatgggtatt ccagaggcat cagcagctct ttctgatggc agcgtagatg ctgcattgat
     3001 tgctggtcca gcagctctta aagctatgaa gtcaggtagt aaacttgtag caaatggtga
     3061 aggtttagta gatggtataa tagtaactgc tgttagcaca gactttgcag agaaacatcc
     3121 agaaatagtt gaaagattta tgaaggttga aaaggaaact ttagaatatg taaataataa
     3181 ttttgatgaa gctatggaaa aagtagctaa agaagttgat ttaagtcttg aagaaactaa
     3241 agaattatat gcttggtatg attttagttt agatataaca gataaagaca tatcttcgct
     3301 tgaagataca caagacttct taataaaaaa taagttacaa gagaaaaaag tgaacataaa
     3361 agaattaatc tataatgcta agtagaaact atgataaaat aatactaagt aagaaatata
     3421 gtaaaagttt aagttacctt attaaggtaa ctttttctat tttgaattag taatttcaat
     3481 ttattttaga atgattagtt gataataatg attaattaat cataaaaaga tactttttta
     3541 tagagtttta ttaagatgtc taataatatg gttatactta tgaagtcagt aattgtgaag
     3601 ttagtaatat gattaaattt atatattgta aaaagattat aatatattaa aattggactg
     3661 ttaatatgat gagtaaatag gtatattagg aggaattata tgagttataa agtatatatt
     3721 gtggaagatg atatatcaat aagtacatta cttaaagatt atattgagaa atatggattt
     3781 gaagtgattg ttgaagaaaa ctttgatgat ataatgatta catttgaaag ttttaagcca
     3841 cacttagttc tattagatgt aaatttacct aaatttgatg gtttctactg gtgtagatgt
     3901 attagacaac agtcgaattt acctataatt tttatatcag ctagagatgg taatgtagac
     3961 caaattagag ctttagaaag tggagcagat gattatataa caaaaccttt ttactatgat
     4021 gtagtaatgg caaaaataaa gagtcatata agaagggtat atggtgaata ttcacctaaa
     4081 atagacgaaa gaatagtgga gctagatgga ttaaagtttt atccagagag gttagaacta
     4141 gaattaaatg gtgagaatct aattataact aaaaaagaag gtatactgat tgaatgtctt
     4201 atcaagagat acccaaaagt agtaagtaga gattatcttt tagaaaagat atgggatgat
     4261 attgagtttg tagaggaaaa tactttaaat gtaaatgtta gcaggataag gaaaagattt
     4321 gaggaattag gtatagataa tgctgttcag actgtccgag ggttaggata taaattaaat
     4381 aagaattggt aaggagaaag tatgaagtta tttttaaaag attataaagg ttatattttt
     4441 atatattata taggcatagt tatgacaatt atttactgta atcttatgaa gtttattagt
     4501 tttggagaga gtttatatat tcttttattt agttctttta tattgttatg ttttttaata
     4561 tataagtatt ataaaaatag agaagtatat aatctgtttg aaaaaggagt acattctttg
     4621 gaggagtcat ttttgtattt aggaagctca ttcttgggga gaaatatatc agttatttta
     4681 aaacaacaac ataaattgta tcaatcaatg atacaagagc ataaaaagat acatagtgaa
     4741 catttaactt tcatcaacca atggattcat cagatgaaaa caccaatatc agttataagc
     4801 cttcagcttc aagattatga gggagaagaa gtaactgaaa atataagaaa agaaatagat
     4861 agattaaata aagggttaga tatggctatg cattttgcaa gggcagataa ttttcagaaa
     4921 gactttatag ttgaaaaagc caaattaaat gaaattgtat ctagtattgt aaatgaagaa
     4981 aaaaggttat ttataaaaag tggaatgatt cctaagattc aagtagacaa atttacttat
     5041 gtttatacag atgtaaaatg gatgaaattt ataataggtc aattaattac aaatggagtg
     5101 aaatattcta aagattatag taactaccta actataaaat ctgaagaaaa taataaatat
     5161 gtaattttaa gtataataga tgaaggaatt ggaattgttt ctaaagattt aaaaagggta
     5221 tttgacccat tttttacagg agaaaatggt cgtaagtttg gagaatctac aggtatgggt
     5281 ctttatctag taaaaaaggt atgcgatgat ttaggtcata aagtaagtat aaaatcagaa
     5341 gtaggaaaag gtacagaagt ttcaatctac tttaataaag atgtaaatag tttaataaag
     5401 gtgtaaatag tttgataaag atgtaaatta tctgttacaa tagggttttt agttaattgt
     5461 acttttttat tatacaattt attaaatgaa atattcatag ttaaataatc aaaatttaag
     5521 agcgtttatt tgcaaacctt acatagatgt aaggtttgtg taatgtttgc agatagttaa
     5581 attttctaat ctaaattaca attaatataa gaaataacat aagagaaata acataaaaaa
     5641 agaaattttg taaaaaagga aggatgttta ttgatgagtt tagatgttat ttttatattg
     5701 aaatcagtca taatagctat agtagagggg cttacagaat ttattccagt ttcatctaca
     5761 ggtcatatga ttttggttgg taatttaata gattttaagg ggcaatttgc tgaaatgttt
     5821 gaggttgtaa tacaacttgg ggctatatta gcagtagtag tactttattg gaaaaagata
     5881 aaagatagcg ttatagaatt ttttaaattt atatttactg gtggaaaaga aggaaagatt
     5941 ggttttagat ttggaatgaa tgtaattata ggttgtatac catttgcgat tataggagtt
     6001 ctattttacg ataatataaa atcattgttt aatttacaat ctgtaattat aggatttata
     6061 gtgggtggga ttttattatt agtagtagaa actttgttta gaaaaaagaa tcattccaca
     6121 gataatatag ataaaattac tccaatacaa gctttaaagg ttgggacatt acaagttttg
     6181 tctgcatggc caggtatgtc aaggagtgca tctactatta tgggtggatg gatagcagga
     6241 cttaattctc ctacagcagc tgagttttct ttctttttag cagtaccagc tatggtggct
     6301 tcttcaggaa aagatttatt tgaatttgat tattcaataa tgacaccaac attgtggatt
     6361 gctttggtag ttgggtttat agtagctttt attgtatcaa taatagttat ggaaaaattc
     6421 gtgaattttt taaagaaaaa accaatgaga gtgtttgctg tatacagaat aataatgggt
     6481 gtagtacttg cagtattagc ttttactaac ataattagtg tatagaaaaa atagatttat
     6541 catctataaa aattaaacta agataaatta taattaacaa ttatatatat gttatttcaa
     6601 aaattaaatt aggaaggata gttaaataat gaaaatttta actgtaaata atttaagtaa
     6661 agtatatggt aaaaaaataa ttttcaacgc attaaatgac ataaatttta gtatagaaga
     6721 tggagaattt gtaggaatta tgggtccatc tggtagtgga aaaactactc ttttaaatat
     6781 gatttctact attgacaagc caactacagg aactatggaa ttaaagggca agaatccttt
     6841 attgttaaga ggtgaggaac ttgcattact tagaagaaga gagttaggtt ttgtatttca
     6901 ggattttaat ttattggata cattaactat aggagaaaat atagtattgc cattgacatt
     6961 agataaggtc agtgtaaaag agcaagatga gagattgaat gaagtatcta caatattagg
     7021 tataaaagat ttattaggaa aaagaacttt tgaagtatca ggtggtcaag ctcagaggac
     7081 tgctattgct agagcattga ttaacaatcc atcaatactt ttagcagatg aaccaacagg
     7141 taatttagat tcaaagtcat caaaggttgt aatggagcta tttcaaaaga taaataaaga
     7201 aaataaagtt actactatga tggtaactca tgacccatta gcagcgagct actgtagtag
     7261 aatcttattc ataaaagatg ggtctatata taatgaaata tataagggta gtagtagaga
     7321 gcagttttat caagagataa tggatgtact tacattattg ggaggcgata actaatgaat
     7381 ataaaacagt ttgctattaa caatatttca agaaatatta aagcgtattt aggatactta
     7441 gcaagtattg ttatatcatc ttcactgcta ttttctttta ttatgtttac aagtcatcca
     7501 gatttagatg tatctcaatt tcctgattat ttaaaagaag gtctcaagat gagtaagata
     7561 attgcatatc tattcttatt cttctttgtg ttttattcag ttagtgtgtt tcttaaaagt
     7621 agatataaag aatttggaat actttatatt acaggtatat caaagcgcca agtaatgaaa
     7681 ttaatcttta tagaaaatat gataataaat atagtatctt ctgtaattgg aataataata
     7741 ggcttaatct ttgcaaagat atttttagtg attatgtcta cttttttaga attatcacca
     7801 ttaaaattct atataccatt taatgcgata ttgtctactt taatctattt tatgatttta
     7861 gctgtattaa catcaatatt tacttctttt atagttaaag aaaatcaggt gttgaagtta
     7921 cttaaaggta caaaaactcc aaaaccagag cctaaaacat cactaatgct tgctatatta
     7981 agtatttgtt tgtttataat agcgtattat aatgctatta cctcaaccga ccaatataca
     8041 acatatctgc gcttagttcc agttacatcc cttactatag tagcaactta cttgttcttt
     8101 tctcaattta gtgtattttt tatgaagaag ctaaaactaa acaagagatt ttatagaaaa
     8161 aatacaaata tgctttggat ttcgaacttg atttataagg taaaggataa tgctagaata
     8221 tttttcttga taactataac ttctgcagta gcatttactg ctataggtac agtttattcc
     8281 ttttggaaag atgtagagcg tcaaattaat ttaatatatc ctaacacaat atattattca
     8341 acaatgacat tgcataatga ccctaaaaag cctgatagca aagaaaaaga caaggaaaga
     8401 atgatgttta tagaaaataa tctaaaaaaa gagaatgtag actatacaag gactaatggt
     8461 gaatttaaaa ctgtatttcc caagaaaagt gattttaatg tcagaattat gaaagaatct
     8521 aagtacttag aaattacaga aactataggg gttaagtcta taagttttga agataatgaa
     8581 tgtatatcat tattatcatc aagtttacca ggaaataata acgtcaaaga aaatattatt
     8641 gtagggaata ggggtttaaa ggtggcaaaa caagtggaag aatgtgttat gccagcatat
     8701 tacaaaaata tgtatgtggt aaaggataat ttttatgata gtatagaatc aaaatttata
     8761 gtggatagat ttactgcatt tgaagtagag gattcaagta aaactataga gatatgcaga
     8821 gaatttgaaa ataaatttaa taatgagtca gggatgcaac catatttgtt tttctctaaa
     8881 gaattaatga taggaactgg gaaattaatg tattctacat ttatattttt agcaatattt
     8941 ataggtttaa ttttctttgt tactacaagt agttttttat ataataaatt ttatatggat
     9001 tgccaagttg ataagaaaaa gtatgaacag ttaaataaat tgggtatgac atataatgag
     9061 attaaaaaag cttcaacaat tgagattgga atagtatttt tgtttcctta tgtagtggct
     9121 gttatacatt caatatttgc acttactgca cttaaaaatt cttttgatat agaagtagca
     9181 tcatcagctg ttttggtaat gggaagcttg ttcttggttc aaatagttta tttttttatt
     9241 gtaagaaata attatttaaa agagataagg ttaaatttag tcaattttta gttactatta
     9301 ttaaatgata ataaaaaggg tttaaaatta attaatatta ctggaattat agatgtttat
     9361 tttttcagta atatttttta ttgtattaac tattaaaatt ttgtacaaat ataaaatata
     9421 atatggtaaa tgtcaaaatt ataaaaaaat tctacttata taaaatataa agaggttata
     9481 tgtacatatg tgtagaaata aataataaaa atatcaatta atgttattag gggggggtta
     9541 ctcattagta aattagctaa tacacttaga atgatgatat taattcaaag cagaggcaaa
     9601 atgaaatgca aagaattatc agaagagttg gaagtaagtg aaaggcaaat aaaaagttac
     9661 aagatgtatt tagagcaagc tggtatattt ataaattcaa cacctgggat ttatggtggt
     9721 tatgaaatag ataaatgtaa tagcatatca ttaattaaat tattagatag tgaagtttca
     9781 atttttatat caactaagtg gtagataagt agaatattag caatatcaac gagtatttag
     9841 aaacttattt tatattaata aagcagtata taaaattgta gaatcaacaa tagcatatac
     9901 taaaacatcc accttatatt aactaaatca tatctaaata aaatacactt acctacaaac
     9961 attataaaat caatacaaaa atgaggtgaa acaaaattta tgataaagaa attaaacagt
    10021 aaagacataa ataaaatcat ggaaatatgg gaaaaaagta caatcaaagc acatgacttt
    10081 ataagtaaag aatactggca aaataactat aatactgtta aaaacgaata tatacctata
    10141 tcagatacat ttgtatatga tgatggagat gaaataaaag gatttataag cataatagat
    10201 aaaaacttta taggagcttt atttataaag cccaaatacc aaaatctagg tatcggaggt
    10261 aaacttttag attatgcaac taaaaaatat aaaagtctaa gcttagcagt atataaagat
    10321 aataaaaaag cagttgtgtt ttataataaa aaaggtttta atatagtaaa agaacaagta
    10381 aatgaagatt caggatttaa agagtacata atggaatata gtaaataata tgattacatt
    10441 ctattaaaag gataattaat ttattttcta gttgattttt taagagtaat ttttaaaata
    10501 gactatatga agataaagat atttattata gatgtaagtt aatcagaatt gatatagcta
    10561 caaaagagga aaataaaatt gtatggtgta tttcagattt aacaaattta ctatttaaag
    10621 ataataagtt tgatataata ttaaagatac tttcacctat aaactataga gtattgaaag
    10681 aattttaaat aattatggaa tgctaataaa ggtttgttaa aatttaataa ttattagatt
    10741 atagaaaatt gccatgaaat tagttcatca agaactagtt tcatagcaat tttaattctt
    10801 ataagtgtat ttatttttac agatttaaaa aacttataca gtatctaata atgtaatctt
    10861 attactttag cctataaata tttaaatctt aaaatgttct ctttgagata agcttatttc
    10921 agagtcacaa tttccacaac agtaaaatgt tgagacatct ttaaattttt cagtattctc
    10981 atcaaagttc atttttttct ttgcaataat tcctacctta gttaaattag aaccacaatt
    11041 attacagttt tgaattttgc ataggttata tagtttatca agtgtaatat cttctaataa
    11101 ttcatcacaa ttacaacatc tgatagaaga aacttcacta cacatttcaa taggttcagc
    11161 ttctttagaa gaaaatttat atgttatgtc atttgatact ttataacctg tatcaaatat
    11221 attagaatta caacttggac ataagtactt tggaagatat atatcttttt tttcaaaagt
    11281 atcactacta atattacagt ttaattcatc taaaattggt ctttcatcta ggttattacc
    11341 tttatttaag cttagaagat aattataaat ttttttatct tcattctgtt ttgatgtatc
    11401 taacaaatgc tccattatat tagtgtattt tttgtttttt gaaggcatgt ttaaatccag
    11461 ataattgttt tcaatagcaa agcatactat attgaaatag ttatatttaa ctgcaaaaaa
    11521 taataacatt tcatcaaata ctttatctat tattttgtca gaaatactta tccaaaaatc
    11581 tggtgactct aagtaaactt tcctactaag ttcatctaac tcttcatcta tattattttc
    11641 attaactttc atatcatcac ttccttttaa atatcttgtg tataaactat ttgttactat
    11701 tttttatata aaataaaatc ttatataaaa atatatcata ttataattta caagtatagt
    11761 ctaaatagag ctgtttttaa gcaaagtttt ataaatgact attaaaatat aaagtaacag
    11821 tataaagttt acttataaat taaatgtaaa cctaaataat tataatagtt gacaaaaaaa
    11881 cgtctttatt ttatactaaa acaaagcttt aatagaagct ttgtatatgt acatataaac
    11941 taaatgaaat aagacatatg aagggaatta taaaaatgaa aaatactaaa gtaaatattc
    12001 aagatttaac taaaatgtca atatgtgtag cattattgtg tatatcatct tacatatata
    12061 taccattgcc atttactcca gcaggagtaa cagcacaaac aataatgata aatttaatag
    12121 ctttgatttt aacaccaaga caagcattta gtacagttgg tgtatatata atgataggtt
    12181 taattgggat tccagtattt ggtggaggta catctggtat tggaaagtta ttaagcccaa
    12241 caggtggttt ttattttggg tttttgtttg cagcactaat tattagttta ttaaaaggac
    12301 gaaataatga tattaagaga tatatattaa taacaatttt tgttggaatg cctattatat
    12361 attttatggg aacagtattt atgtgctatt ttaatcaaat gacagtagaa gcagcacttt
    12421 ttgcagcagt agtaccattt ttaattggag atacaataaa gtcagttatt gcatcttttt
    12481 taggcactaa actgaacaat gtactcagaa gaaatctatg ataaatctat aatataagga
    12541 agggtgtaat gtatgaagga agtttttata ttaggaggat tgagaagtca tataggtcta
    12601 aaaaatggaa tttttcaatt tgttcaacct gaattactag gagcaagtgt tttaaaagat
    12661 ttaattaaaa agtatgaaat tgacaaaatt gatgagatta tatgtggaaa tgcagttggg
    12721 acaggaggga atatagctag attaatgact ttaacagcag gagtgtcaaa tgaagtacct
    12781 gcttttactg tggatatgca gtgtgcttct gctatgatga gtatagacat agctttttca
    12841 aaggttaaat ctggtcagtg tgatttaatt attgcaggtg gttttgaaag tagttctctg
    12901 caaccaatgc gcacatatca taagaatgat aagcgatata atacaaataa tccaaattat
    12961 acagttgctc aattttctcc tgatgataat agccaaaata gtatgctcga aggtgcggaa
    13021 agagtagcag agttatatca aattgagaaa gcagacttgg atttttgggt aaaggaaagt
    13081 cataaaagag caaaagaagc aagagaggaa aaaatacttg aagatattat atctcctata
    13141 aataatagta cctatgatga aggtatacgt gataagatga gtcaaaggtt attagatagg
    13201 atgccatcaa ttttaggaaa agaaactatt acaaatgcag caaattcatg tcttattaat
    13261 gatggagctt catttattat aatatgttct aagaagtatt tagaacatgt aaaaaagaag
    13321 cctaaagcaa aaattattaa cacatgcacg ataggaacag atgcaacctt aagtccaaca
    13381 tcagcgatac aagcaatgga taaactttta gagatagaaa gccttaatta tttagatgta
    13441 tctgctgttg aatttaatga agcatttgca gttatagatg tgttgtttca aagaaagtat
    13501 ccagagttaa tagatagata taatatattt ggtggagctt tagcgtatgg acatccatat
    13561 ggtgcttcag gtgcaattat tgcattacat cttttaaaag cattagaaaa gactaagggt
    13621 agatatggaa tttgctctat agctgcagct ggtggtctag gttcagcttt actgcttgaa
    13681 agggtgtaga ttatgaacta ttatgaactt ttaagaataa aaaaagagag gcataaaaat
    13741 aaaaattttt taattataga tggagaaaaa tatacttatg aaaatatatt gagttatagt
    13801 gaggaactag gaaagcaaat ttctttaggt gaaaatatcc caattttaat atattctaaa
    13861 aatataatgt ttcagttgat tagttttttt gctattaatt attcaaaaaa tattcctatt
    13921 atttgtcatt ataatctttc taaaaaagta ttagatgata ttttattaaa aaataatatt
    13981 tcaatcatta tatctgatga atctatggac gttattgatt tatatgatga taacaataat
    14041 gaagtagcaa aaaaagttaa tttttctatt tttaatccta aatttaatat atatatgtat
    14101 caatataaga agcttataaa ttatttagat aaaagtattt gtatgggagc tttatcttca
    14161 ggttctacaa gtgttccaaa ggtattatat agaacatatg agagttgggc tggatttttt
    14221 cctatacaaa atggtatttt taatatctct ggggaatcaa tcttgtttgt taatggaaca
    14281 cttagtttta cagggaatct aaattctata atgtcagtat tatatgaagg aggtagtatt
    14341 gtaataagtt caggtcttaa ttgtaaatca tggataagga caataaaaca atataatgta
    14401 actaacatat accttatacc tacaaaactt caacttttgg ttaaacactt aaaagaacca
    14461 gtactcaaag ttgtaagtat ttttacaggg tctcaattat tatttgaaga tactgcaaga
    14521 aatctaaaaa aatatatgcc aaagtctgaa attattttat actatggggc aagtgaatta
    14581 aattatatta catatttatg ctatgatgaa ctaattgaaa aacctctaag tgtaggcaga
    14641 ccatttccag gaatagatat atatattaga gaaggaaaaa tttttgtgaa tacagaatat
    14701 gcagtatata atgcaaccaa accttattct gtcaatgata ttggatatta tgataatgat
    14761 ggatacttaa tatttgaagg aagaagtgat gacattataa atattggagg atttaaagtt
    14821 agttctacta agattgaaaa tgaagttaaa aaaattcctc aaattgaaga tgcaattgta
    14881 ttgccgtact cagacactat aagaggaaat caaattgtat tatttgtaat aactatagac
    14941 aaaattacga agaaagattt gttgattaaa atgaaagata atctaatgaa aaatgaaatc
    15001 ccaaagaaaa ttatcttttt aaattcattt ccatatacct cttctgaaaa gatagataga
    15061 ttagcattat taaaaatgtt ataagtataa tatttagtaa ttttagtgaa ccaatgtatt
    15121 gataaaaaca tattgtatat agtaaaggag gcttacaata tgtcaaatca atacgatata
    15181 actgttattg ggggagacct gcgacaagtg tacatggtaa aaaaactaat taataaaggg
    15241 tattctgtag tcacttatgg gatatcaaat gaaattataa atggaatcgt tggaaaatca
    15301 acttcactag ctgaagcact atccaaaagt tccattattt tatgtccaat tccatttaca
    15361 aagaatcaag ttaatattga aaatacggat gattgtcttg atgctactat tgataacttg
    15421 ctaattaatt tatctcctaa tcaaatatta tttggaggta acataccaac taaagtttgt
    15481 aaattttgcg agcaacactc tattcagatt tatgatttta tgaaaatgaa tgatgttgct
    15541 attttaaatg cagttgctac agctgaaggg gctatagcag aagctattaa aagaagtata
    15601 atcaatatac atcaaagtaa ctgtttagta ttaggttatg gaagatgtgc acaaatactt
    15661 gcaaaaaaat tatacgcttt ggatgcaaat gtatgtgttg gcgcaagaaa taatgatgca
    15721 agaagtacgg ctaatgcatt tggatattcc agtatttctt taagtcaact tgatgaaaaa
    15781 cttttacaat ttgattatat ttttaacacc ataccagagt gtattttaac gaaagaaagg
    15841 ttagaaaaag tatcacaaga agtaactatt atagatatag cttcttctcc tggaggagta
    15901 gattattctg ttgttaaaga agcagggatt aatgcgactc tttgccttgg gcttcctggt
    15961 aaatattcac caaagacatc tggtgaaatt cttgttaacg ctatagaaaa tattataaat
    16021 gaaagaaggg attagaaatg agacttgaag gacttacaat tggagtagga tttactggtt
    16081 cgttttgtac ttatgataaa atatttatag agttagagaa tttggttaaa gaaggagcta
    16141 atgtacacac tatattttca gatgtatcac aaaatatcga ttgtagattt ggaaattctg
    16201 aagagtttat gaaaaaagca tatgaactta caggaaataa acctatagtt acgattgaag
    16261 aggcagagcc atttggacct aaaggaattg ctgatattat aataatagct ccttgtactg
    16321 gaaatactgc tgcaaaatta gcaaatggta ttacagattc accagtatta atggcagcaa
    16381 aaggtcatct tcgtaatgat aaaccactag taatatcaat atcaacgaat gatgctctaa
    16441 gctttaattt caaaaatatt ggcattctcc ttaattctaa aaatatatat tttgtacctt
    16501 ttggtcaaga taattgcaaa gcaaagccta attctatgat tgcacatact gagctaataa
    16561 ttccaactat agaacttgct ctagagaaca aacagctaca gcctgttata aaaagtccac
    16621 atcaatagaa ttggttctta taatattatg tattagatac aatactagca aagaggctgt
    16681 ctcaaaatag agagaagcct ctttttcttg ttgaaatgat gaaaatatat ttaatttcat
    16741 acaaaaaaat gcctcatgga ctaaaaagtc tattttgagc taatctccgt aatttttgct
    16801 atattaaaat tatttactta atccaatttt taaattagaa tttatatcgt tttgactctt
    16861 caaatatcaa tctaactgtt gttgatacaa aagaagagga cataattaaa acaaatactg
    16921 atagtcctct aataaacaaa ttatctacat aataagttac tattccaata cctccaatcg
    16981 ttaaaattac acttataatc aaagaaaaaa cgctaattgt ttttaatttt tccatgctta
    17041 tcctccttct tataaacttc aaatttatct atataatatt aaatatattt tatttcatat
    17101 tatataaaaa tcat
//
LOCUS       DAEHWO010000093        17084 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEHWO010000093 DAEHWO010000000
VERSION     DAEHWO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17084
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.093"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(216..1259)
                     /locus_tag="KNP54_003351"
     CDS             complement(216..1259)
                     /locus_tag="KNP54_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBF0894212.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(1280..1726)
                     /locus_tag="KNP54_003352"
     CDS             complement(1280..1726)
                     /locus_tag="KNP54_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBF0894213.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(1900..3480)
                     /locus_tag="KNP54_003353"
     CDS             complement(1900..3480)
                     /locus_tag="KNP54_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBF0894214.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            4279..5181
                     /locus_tag="KNP54_003354"
     CDS             4279..5181
                     /locus_tag="KNP54_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894215.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVLGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            5168..5923
                     /locus_tag="KNP54_003355"
     CDS             5168..5923
                     /locus_tag="KNP54_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0894216.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            6020..7057
                     /locus_tag="KNP54_003356"
     CDS             6020..7057
                     /locus_tag="KNP54_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0894217.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            7866..8768
                     /locus_tag="KNP54_003357"
     CDS             7866..8768
                     /locus_tag="KNP54_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894218.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIISFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            8755..9510
                     /locus_tag="KNP54_003358"
     CDS             8755..9510
                     /locus_tag="KNP54_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBF0894219.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            9641..10663
                     /locus_tag="KNP54_003359"
     CDS             9641..10663
                     /locus_tag="KNP54_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0894220.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(10827..11384)
                     /locus_tag="KNP54_003360"
     CDS             complement(10827..11384)
                     /locus_tag="KNP54_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBF0894221.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPIKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(11390..12466)
                     /locus_tag="KNP54_003361"
     CDS             complement(11390..12466)
                     /locus_tag="KNP54_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBF0894222.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(12467..13150)
                     /gene="modB"
                     /locus_tag="KNP54_003362"
     CDS             complement(12467..13150)
                     /gene="modB"
                     /locus_tag="KNP54_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBF0894223.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(13299..14111)
                     /gene="modA"
                     /locus_tag="KNP54_003363"
     CDS             complement(13299..14111)
                     /gene="modA"
                     /locus_tag="KNP54_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBF0894224.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            14304..15233
                     /locus_tag="KNP54_003364"
     CDS             14304..15233
                     /locus_tag="KNP54_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894225.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(15394..15843)
                     /locus_tag="KNP54_003365"
     CDS             complement(15394..15843)
                     /locus_tag="KNP54_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894226.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(16046..17026)
                     /locus_tag="KNP54_003366"
     CDS             complement(16046..17026)
                     /locus_tag="KNP54_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0894227.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDRPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         5891 a         2727 c         2090 g         6376 t
ORIGIN      
        1 ttttatataa tattatataa cactttttac attagtaaag gataaattgt ataaaaattc
       61 tgttaattta tttttataat ttcatctttc taataaaaac aaagaagaag acttaaaaat
      121 ttataagtcc tcttcttttc aacgtgcatt tttgtgctat atttaattaa ttcgaccttt
      181 aatttccata tccttcctat gataacaaaa ctcttttatt tttttaatga ttcattatca
      241 tttaaaactt cttttatatc aagtacttct ttgttatcat cactcataac ttcctttatt
      301 cctttgaatg ttcctaggaa attaactgct tctgaaggta aaaccagttt tgttgactta
      361 ccttcagcca ttttttcaag agcttccata gattttaatg ctagaatatt attgtctata
      421 tcagcctctt tcattgctga aaaaactaat tttaaacctt ctgctgttgc catttgagtt
      481 ctttttatca tttcagcttc accttgtgcc ttagcaatag ctgtctgtct tatagcttca
      541 gcttcacctt ctgccactaa tatagcagat tctttttcac cttctgctac acgtaccata
      601 gcttcttttt tggcttctgc tgttaatata gcagattgtt tttcaccttc agcttgaagt
      661 attgcagctg acttattacc ttctgcttga agtattgcct ctcttctttc tctttctgct
      721 ctcatttgtt tttccattgc aacttgaata tcctgaggag gcattatatt ttttaactct
      781 actctattta cttttatacc ccatttatct gttgcttcat caagaatagt tctcattttt
      841 acatttatta tatctcttga tgttaatgtt tcatctaaat caagttcacc aattatattt
      901 cttagtgttg tagctgttaa attttcaata gcagctattg gattagctat ctcaaacaca
      961 tatctaactg ggtctgtaac tttataatat acaactgtat caatctgcat agttacatta
     1021 tctttagtta taactggttg aggtggaaaa tctattacaa tttctctaag gtcaattaca
     1081 tatgccattt tatctaaaaa tggtattaag aaatgtacac ctgtttcagc cactttttga
     1141 aacttaccaa gtctcattat tatacctact ttagattgtt ttataactct tatacaagtt
     1201 aaacttattg ctacgactac tactattaat acaatactta aaacaatttt agtacccata
     1261 ctataaatcc tcctttattc tattggtttg tcacattaac tgtggcgtct acttttttaa
     1321 caactaattt taccccttca atttttaata cttctactgt agaacctttt tctatctttt
     1381 caccatctat agaaatagcc gtccatgttt catgttcaac tacaactaga cctgtgttat
     1441 ttggagaaat ctcttctgta acaatacctt ttttagacat cattgcttgt aaattagtgt
     1501 tagatttata gcctttatct ttttttacta tttttttagt agctacgact aacattgcta
     1561 tagaaattac tgcaaatatt aaaatttgta agaaaatact ctctataaag ctacttaaaa
     1621 atataagtat tacagctcct acactaaacc atatcaatgt taagcttggt gttaacattt
     1681 ctgctattcc aaataagact gctactatca accatattag cttcatacta tctaccctct
     1741 tttcatatga attataaaac cctatataaa ttatatgttt atacaatgtt tttgaatata
     1801 aatttaaatt acaaaacaat aaaataaatt aattaattaa tagtattata tcaacatact
     1861 ttgttaaaat tgttacaaag tagtatcaaa tatcaccaat tatatatcca acaactcttt
     1921 cattgttaat gaaatgttac ttattaaatc cgtagcattt accgtataca ttgctttgct
     1981 caatttatct cctatatagc catgtatata tgctccacta actgtagctt ccaatatatc
     2041 cataccttga cctataaatg aagtaatcat tccaagcaaa caatcaccca ttccaccagt
     2101 tgccatacag ctatttcctg taggatttat atatgttttt ttaccatctg ttatgacagt
     2161 ttgataacct tttaaaagca ccaccagatt atatttttga gcaaattctt ttgcaacatc
     2221 tactctatgt tctcttatat acccaattga atctcctgtc aacctggcca tttctcccaa
     2281 atgaggtgta attacaaatc tatttttcca ttctaaaaac ttataacatc tgtccttcat
     2341 aacgttcaat ccatctgcat ctaatactat tgggcaatta gaattttcta ctatcttaag
     2401 taatttatca aatgtttgac tattatctcc catacctgga ccaaaaccaa ttgcatcact
     2461 agaattaagt aatttattta atctttcttc ttcaaaattt aaagtcattg cttctgtaag
     2521 tctaatagat accttttctt gcacatcttc actactaatt aatgttacaa gtccactccc
     2581 actcttaaca gcagattcag ttgctatgaa acttgcacca taaaatcctt ttgaacctgc
     2641 aactatagat acttttccaa aatcactttt aaaaccatgc ttatctcttc ttctaatatt
     2701 attttttaca aaagtcttat cagttatgaa ctcttcatca tggtattttc ttgtaataaa
     2761 atctggaaca cctatctttt ctacaactac atcacctata agtgcgctag tgtcatagtt
     2821 tagaaaacct cttttataaa actcaaagct aatcgttttg tttgctctaa tacaagttcc
     2881 taatacattt ccattatcgc tatctatacc tgaaggaata tctatagaat acgtattttt
     2941 gctattatcg tttactatgt caataacttc tttaaaaata ccagttatat cacgttttaa
     3001 tccagtccca aatatagcat ctactacaac atcactttta gatactctat ctttaaaaat
     3061 tgttaaattt ttatttttta taatattttg tttctcaact ttaataattt tatctacttc
     3121 attttcctct ccataatttt tttcacttaa atcattttta ttaatattta taatattaat
     3181 tcccatattt aaaagtacat tgtaatttat tttagagcat tcacttagtt tttcaagatt
     3241 acctactaaa aatacgttta cttcttttcc atatgtattt agatgtcttg ctattccaag
     3301 accatctcct ccattatttc caacaccaca tacaactgta taactattat acatgtctat
     3361 atccatattt ttcattgcag atataaccgc attttccatc aatacaatca ttggaatccc
     3421 tacttcttct acacatgcag tatcaacatt tctgcttaat ttagatgtac ctattagcat
     3481 aaattatcac tcctataaag ttaaagactt cttaaatact taccaaaaat atctattgaa
     3541 atctttttaa tcccataaat atcataaata aaatcactaa aactaagagt tttgaaataa
     3601 tttaaaataa caaaaaattt tgaattaaaa caattattta atttattata ccatataatt
     3661 taagttatta tgttgattta aaacctattt acactaatta tctaaatatc tctttatttt
     3721 tataatcttt tataacttat ttatattttt catttttata aaaaaacaat aattaagaat
     3781 ataactatat tctacatgta aaaatttttt tatttaaact caattttctg ataatttgat
     3841 aatttttcaa aatttatagt tgacttttat tttttactgt attaaactaa ttactataca
     3901 aaacagaaaa caaaattttc aaaattatta aattaaaagg agaggtaaat atgaagactt
     3961 tattaaacaa acaagtacga ttttttagta gccaatttag ttagggtttg tacctaagtt
     4021 aagacaaatt gtcataacat agatacaagc cccttaggat tatgattttt aaggattgta
     4081 tctatgttgg ctatagtaat tgttgttaaa gtttttattt tatcatcata atatagagcc
     4141 acatggatta tactgtgtgg cttattcgaa tttttgccat acagttatat atactgtgtg
     4201 gtttttttat atcaaaatca ttttttaaaa ccaaatttta aaaaccattt aaaatatttt
     4261 caaaggggtg ttttatttat gtcaggtatt atatctgtaa tgacgcaaag tttaatttta
     4321 tcgattatgg cactgggggt ttatataact tacaaaatct tagattttcc agatatgtct
     4381 gctgatggta gctatacaat gggtgcttct attgtagcat tttctcttac taatggtatt
     4441 tctcctgtag tagcaacttt aatggctatc ttatgtggtt gtactgctgg tcttgttaca
     4501 gggattcttc acattaagtt taagatatct aatttacttt ctggtatttt agttctggga
     4561 atgctatact ctatcaattt aagaataatg ggaaaatcaa atattcctct atttagcttt
     4621 aaacacttat tcaatgggga aatatctcct atagttttag ccttagcttt tgtattcatc
     4681 tgtaaagtcc ttttagattt attcctaaaa acaggtcttg gatacacttt aaaaggtgtt
     4741 ggtgataact ctcaaatgat taaatctcta ggtataaata taggttctat aaaaatacta
     4801 ggacttatga tttcaaatgg acttatagct ttatctggta gtcttatggc tcagttcttg
     4861 ggattctcag atgtaaatat gggtatagga actttagttc ttggaattgc ctctatcata
     4921 attggtatta cactatttaa gaaatttact tttatcaaag atactactgc aataattgtt
     4981 ggctctttta tataccaatt cactatatac tttgcaatga gtttaggaat gttatcaact
     5041 gacttaaaac taataactgc catagttata atagctttcc tagctactgg taacttaaat
     5101 atttcactaa aaaaaaacaa atgcaaagct agtaccaaaa ataaatcaga aaaaagaggt
     5161 gttgtagatg ttacaaatta aaaatctttc aaagagtttc cctaatccat atggtgaacc
     5221 taatactatc tttgaaaatt tatcaatcga tatagaagat ggtgaatttg taagtatcat
     5281 aggtagtaat ggaactggta aatctacttt attaaatata atatctgggc ttataaaaga
     5341 atcttctggt caaattactt tagatagtac tactataaca aatttagctg agtataaaag
     5401 aactcaaata gtaagtagag tttttcaaga cccaagcctt ggaacttgtc cttctatgac
     5461 ggttagagaa aatttatctc tagcacttaa taaagggaaa ttattgaact taaaaaaatg
     5521 tcttcgtcat aaaacgaatg acttggaaca cttacttgaa ggaatttctt tggatttaaa
     5581 aaaatattta gatattaaag tacaatatct ttcagggggt caaagacaat cactatcact
     5641 aattatgtct agcttagcaa gtcctaaggt cttattacta gacgaacata cagcagcact
     5701 tgacccaaaa acatcaaatg aagtaataga gttaacagat aaaatcgtaa gagagaaaaa
     5761 tataactaca cttatggtta ctcacaactt gaaacacgct cttcaatatg gagataggtt
     5821 gataatgctt cataagggtg aagttgtatt agatgtaaaa gataaagaaa aaaaagattt
     5881 aacagttgaa gaaatcttag aaaaatttga atatgcagta taagaaatta aaatcttagt
     5941 tttaatcaga aatatttata atctatcata tgaatatatg aacaaatata attattaaat
     6001 tttaagggag gaaaataaaa tgataaaaag taaaaaaata ttaagtttaa ttatagcagg
     6061 agtacttggt gtatcaatgc ttactggatg ttctcaaaat gatggctcca atgcttcaaa
     6121 tgaaaataaa gaaacagata gcaaaaaaca aaaaaatata ggtattactc aattagtgga
     6181 acatccatct ctggataaag caaagaaagg attcatcaaa gcacttgaag ataaaggcta
     6241 taaagatgga gataatataa aaatagattt ccaaaatgca caaaatgata tgcctactac
     6301 acaaagtatt gctagtaagt ttgtatccga caaaaaagat ttgatatatg ctatatctac
     6361 tccatctgca caagcagctt ataatgctac taaagatatt ccaataataa tgactgctgt
     6421 tacagaccct gtagaagctg gacttgttaa atctcttgaa aaaccaggtg gaaatgtttc
     6481 tggtacatct gattatcttt caattgataa aacattagaa ttggttaaaa cattgactcc
     6541 aaaagcaaag aaaatagggg ttatatacaa tactagtgaa gttaattcaa aaatccaagt
     6601 tgattctcta catgattatg ctaagaaaaa taattatgaa gtagttgaaa aaggaatcag
     6661 ctcttcaagt gaagttaacc aagctatttc tagtttagtt ggtaaaatag atgttttata
     6721 tgtccctact gacaatttaa tagtttcttc tatgccaata gtttctaaag ttgctaatga
     6781 aaacaagatt cctataatag cctctgaaga aggttctgta tcttctggtg ctttagcttg
     6841 ttgtggaata gattatgaaa aactaggtta taaggctgga gaacttgcta ttgaagtatt
     6901 agaaggaaaa tctgttggcg atataccagt tactacatta gatgaaactg aaataataat
     6961 taacgaagat acactaaaag cacttgacat gcaaaagtta tcagcagata atataaagta
     7021 tataaagtca gatgaaaatg caaaatctac aaaataaaac ttattaattt caaaaaatag
     7081 gtaatatgaa gtaggtaata tgaaaacttt atataataag tactcttatc caccctaacc
     7141 ctttgaaaat tgtgcttatt gtagcaattt gaatattgca tataaagtta ttcattttcc
     7201 ataaaagtcg tctatattga cgactgatta tgaaagttat ataactttct aatcactact
     7261 tgagctgtcc aaaagaattt taatattctc cagacagctt ttttttatga tatttgattg
     7321 atatacatgt ctagttattc catatttagt aaatattttg ataaaatttc cacattcact
     7381 tataacttag gataacgttt ttttcaaaca atacattaat ttaaaagtat tctgagtata
     7441 cattatttag tattttaatt aaatttagca gttgactttt attattgtat aatttataat
     7501 ttataacaag tcgagaatac atataatttt ctgactaatt aaaatattaa aagggagaga
     7561 taattatgaa tactttatta aacaatagaa aatattatta ttattatagc cactattttt
     7621 agggtttgta cctacgtttt aacatagata cagacccctt aagactacta aaattttggg
     7681 attgtatcta tgttggctat attgtttata aagttttcat ctaactatat aagagccaca
     7741 tagattaaac tatgtggctt attcgtgttt ttaccacata gttttgtaca ctatgtggtt
     7801 tttttataca caaaattagc aaataattaa aattataaaa atattttcaa aggagtgttt
     7861 tatttatgtc aggtattata tctgtaatga cgcaaagttt aattttatcg attatggcac
     7921 tgggggttta tataacttac aaaatcttag attttccaga tatgtctgct gatggtagct
     7981 acacaatggg tgcttctatt gtagcatttt ctcttactaa tggtatttct cctgtagtag
     8041 caactttaat ggctatctta tgtggttgta ctgctggtct tgttacaggg attcttcaca
     8101 ttaagtttaa gatatctaac ttactttctg gtattttagt tatgggaatg ctatactcta
     8161 tcaatttaag aataatggga aaatcaaata ttcctctatt tagctttaaa cacttattca
     8221 atggggaaat atctcctata gttttagcct tagcttttgt attcatctgt aaagtccttt
     8281 tagatttatt cctaaaaaca ggtcttggat acactttaaa aggtgttggt gataactctc
     8341 aaatgattaa atccctaggt ataaatatcg gttctataaa aatactagga cttatgattt
     8401 caaacggact tatagcttta tctggtagtc ttatggctca gttcttggga ttctcagatg
     8461 taaatatggg tataggaact ttagttcttg gaattgcctc tatcataatt ggtattacac
     8521 tatttaagaa atttactttt atcaaagata ctactgcaat aattgttggc tcttttatat
     8581 accaattcac tatatacttt gcaatgagtt taggaatgtt atcaactgac ttaaaactaa
     8641 taactgccat agttataata tctttcctag ctactggtaa cttaaatatt tcactaaaaa
     8701 aaaacaaatg caaagctagt accaaaaata aatcagaaaa aagaggtgtt gtagatgtta
     8761 caaattaaaa atctttcaaa gagtttccct aatccatatg gtgaacctaa tactatcttt
     8821 gaaaatttat caatcgatat agaagatggt gaatttgtaa gtatcatagg tagtaatgga
     8881 actggtaaat ctactttatt aaatataata tccgggctta taaaagaatc ttctggtcaa
     8941 gtattattaa ataaacataa cttgtctaat ttagctgaac acagaagaac tcaaatagta
     9001 agtagagttt ttcaagaccc aagtcttgga acttgccctt ctatgactgt tagagaaaac
     9061 ttgtctttag ctcttaacaa aggaaaacta ttaaatctaa gaaaatgtct tcgttacaaa
     9121 agagatttct tagaaaattt attggaaggt gtatctcttg atttaaaaaa ataccttgat
     9181 gttcaagtaa aatttttatc aggaggtcaa agacaatcat tatcactaat tatgtcgtgc
     9241 ttaacaaatc catcagtttt attacttgat gaacatacag cagcacttga cccaaaaaca
     9301 tcaaatgaag taattgaatt gactaataag attgtaaggg aaaaaaatat aactacactt
     9361 atggttactc acaacttaaa acacgctctt cattatggtg atagattgat aatgcttcat
     9421 aagggtgaag ttgtattaga tgtaaaaggt aaagaaaaag aacaattaac agttgaagaa
     9481 atcttagaaa aatttgaata tgcagtttaa aataatatat ctattgtatt aaactcggct
     9541 ttaaaataaa gttaaaatta caataattat ggttactttg taataattca tatgaatata
     9601 tgaacatata taacaataaa tttttgaggg ggatataaaa atgattaata aaaaaagatt
     9661 ggcaagtttg attttagctg gtgctcttag tatatctatg cttacagggt gttcacaagg
     9721 aggagactct ggtaattcaa aacaagaaag taattctaaa ggtaaagaag ttaaaaaaat
     9781 tggtataact caactggttg aacatccagc attagatgcc actaggacag gttttgtaaa
     9841 agcattagaa aagaacggat ttaaagatgg agaaaatatt gatatagact tccaaaatgc
     9901 tcaaaatgac atgcctacta cacaaagtat tgcgagtaaa tttgcatctg ataagaagga
     9961 cttaatattt gctatatcta ctccatcagc tcaggcagca tttaatgcta ctaaagatat
    10021 acctatactt attactgctg tgagtgaccc tgttgctgct ggattagtta aaactcttga
    10081 aaagccaggc acaaatgtat ctggaacatc agattttgtt tctgtagaca aaggtttaga
    10141 acttcttaaa atatttgctc ctaaggcaaa aactatagga gttatgtaca atactagtga
    10201 agtaaattcc aaagttcaag ttgatgcttt aaaagaatat gcatctaaaa atggatttaa
    10261 agttgttgaa aaaggtataa ctacttcaaa tgaagttaac caaggtattt ctagtttagt
    10321 tggcaaaata gacgtattat atgtccctac agataactta gtggcttctt ctatgcctat
    10381 agtctctaaa atagctactg agaataaaat acctgttata gcagctgaat ctggtccagt
    10441 tgaaaaaggt gctcttgctt gtcaaggtat caactacgaa aaactaggtt acaaaacagg
    10501 tgaaatggca gttaaaattt taaatggcga atcagtatct gatatgcctg tggctacatc
    10561 agatgataca gatatcattg ttaatgaaga tatattaaaa gctttaggta tggaaaaacc
    10621 ttctaatgaa aatatttctt atgtaaagac taaacaagaa tagaaagata ttttctatat
    10681 acgattaata tgcctgtttc tataaattaa tttatagaaa caggcatata tttttatttt
    10741 aatgtattat ctatttaaag attatatgta aatgctctta atttgtttgt ataaatttta
    10801 cttgtataaa ctttatacaa tcatatttat tcttctattt tctttattac tctacatgga
    10861 tttccaacag ctacagtatt tggtggtata tcttttgtga ctacacttcc tgcacctatt
    10921 actacattat cacctatagt aattcctggt gttatgatta ctcccccacc tatccataca
    10981 ttatcaccta tttttatagg agaaccatac tctatgcctg aatttctaag ttgtgcatca
    11041 attggatgat aggctgtata gatttgaacg tttggagcta acattacatt gtcacctatt
    11101 tcaattttac atacatctaa aaaaatacaa tcataatttg caaagaaatt ttcgcctaca
    11161 tgtatgttat atccataatc acacctaata ttttgttcta catttatttg cttgccaact
    11221 gaaccaaata gttgtcttaa aatatcttct cttttttcat attcatcctc taaagtatta
    11281 ttaaacaatc tagttaattt tttacaatac tctctttctt ttactaacaa ttcatcattt
    11341 gcatagtatc ctttcccaga caacattttt tctttttcag tcatatagtt tactcctttt
    11401 tgttataatt gtatctaaag caaaataaat attcctgtgg aaaatctaaa tatattctgt
    11461 cacctttctt aaatctcatt ttactttttt ccaattctat ttgaataggt acacattcgt
    11521 tagataaatc agtttttcta acatatatag tatatgtaaa aggattttct acaatgttaa
    11581 tcaattcgaa acataacttt tcatttaaat cttcattaga atccaagacc ttaatatgat
    11641 gctccctgat tcccacatat tctatattat cacctatttc tctatttaat gtcaactcgc
    11701 atccccagtc tgtagcataa atagtatttt tatccagtct atttaatttg gatatatttt
    11761 tacaccctgt tatcttagct tctataaggt actttggaga ttcaaagagc tcttttttag
    11821 gtctctttgg aagaccttct cctttgttgt acactataat atcatcacaa actcggtaag
    11881 cttcttcaat atcatgagta acaaatagta tatctccctt gtaatctttt aacatattca
    11941 taagttcttt ttccatattg cttcttaaat gatggtccaa tgctgagaaa ggttcatcta
    12001 aaagtaatat atctggagat gttgccaatg ctctagctag tgctaccctt tgttgttgac
    12061 caccagataa ttgccaaggg tatctcccct caaacccatt taatttaagt atatctaagt
    12121 accttgctac tatttccttt ttttcactct tacttagttt taaaagccca agttctatat
    12181 tttgacttac agtcatatgt ggaaacaaag catagttttg aaataaaaat cctacctttc
    12241 tatcttgtgt tgataaattt atcttctttt cagaatcaaa tagaactcta tcatttaata
    12301 caattttacc tcttgttggt ttctcaagcc ctgctataca ttttaatgtc atactttttc
    12361 cagaaccaga ttctcccaaa aaccccagag tacctttttc ttgtttaatt tctaccttta
    12421 gtttaaaaga ggataaatct ttttcaatat ccacgtataa gctcaactat ccacacctct
    12481 ttcctataat tttctgctga aattccgacc aataatttag taataaaatc attgctatag
    12541 atattgctac aataatcata acccacatca tagctttatt catatctccg ccttcaacag
    12601 caaaaaatat agctattggc atagtttgag tttttccagg tatatttcca gctatcataa
    12661 gtgtagcacc aaattctcca agagctctgg caaacgacag caccaatcca ccaattattc
    12721 caggccatgc taatggaact gcaatcttaa aaaatacttt ccattcatta agacctaatg
    12781 ttctagcagc tgacaacata ttattatcaa tctgttcaaa agctgacctt gaagttctat
    12841 acatcatagg aaaagacacc actactgctg aaattacagt tgctgtccaa ctaaatatta
    12901 aagtcctatc gaaatttaat aaaaactttc ctataaatcc attcttccca catagtaata
    12961 ataaaaagaa acctacaact gttggtggca aaattagtgg aagtgtaaat agtccatcta
    13021 taagaccctt ccacttacct ctatagttag ccataatata tgacacaaat attcctatta
    13081 caaaagttat tattgttgac aaaatagatg tcttaagtga tatccataag ggtgaccaat
    13141 ctgttcccat ctttccctcc ttaattttaa atggaaatag tgaaactaat aactctatta
    13201 atttcactat ttccatttta ttataataca caattatttt caattttcat ttatttatat
    13261 ataatttata cttaattaca cataatttat ttctaagttt attctacttt tttatatcca
    13321 aattcttcaa aaatcttttg tcctgactca cttaataaaa attcttcaaa tttcttagca
    13381 gcatctacgt ttttactagc tttaattact gaaactggat atgtaatagg cgaatgagtt
    13441 ttttcgtctg ttttttcaac tacttttatc ttatcattat tgacagtatc actgaagtaa
    13501 acgaatccaa catcagcatt tcctgattgc acccatgcta aaacttcttt tacatctttt
    13561 gcaaatacta gcttatcttt taacttatct tttaaattta aattagttaa cacctcatct
    13621 gcatacttac cagctggaac actttcagct tcaccaacag caattttctt cactttatct
    13681 gtagtcaaat ctttcatacc tgatacacta ctgtcagcag aagaaataag aactaaatca
    13741 ttttttacta aatctttcat agtatcagaa actaataact tctcttcatc caaagctttc
    13801 atttgttttt gacctgctga aataaataaa tcacaaggtg ctccttgttc tatttgttgt
    13861 tgtaatgagc ctgatgctcc atagttaact gtaagtttta catttgaatc aactttttta
    13921 tattcttctt caatctttgc cattgcttct tttaaacttg cagcagccga tatatttaac
    13981 tctactgaat cactactttt agttgttttt tcttgttttc catcatcttt tttgtcttca
    14041 ttactattgc acccaactgt ccccaaagtt aaacatgcaa ctaatcctaa tattcccaat
    14101 atttttttca taacaatctc cctttttgta aatttgatac acattttaac atgttttatt
    14161 atgttttatc atgttttgtt atatatagtt taattatata tacatgataa taaattttca
    14221 agtaatttat ttacactact tttaaatatt ttgctacatt ttcctttttt taatgttaaa
    14281 ataaccttat atggaggtgg attatggact cattatcatc tttgacacct gtcgaggtag
    14341 ctgaattatt aaagataaca aaaaatactg tatatgaatt aatcaaaaga ggtgaacttc
    14401 cttcttataa agtagggaaa aaaataagag ttgatactaa agatgttgaa gaatatatca
    14461 acagccaaaa aactggtaaa gtaaaggata cacatttcaa caataaaaat atagatataa
    14521 ataataattt caaaattatt atttctggtc aagatgtaat attagacatt ttagctaggt
    14581 ctgttgaaaa aaaattggat ggaataagta catttcgctc ttatataggt agttataatg
    14641 ctttgtatga gttatataat ggcagagttt ctatagcatc atcccatcta tgggatttcg
    14701 aaacggatga atataatagc acttttgtta aaaagctatt gccaggaata ccatgtgtac
    14761 ttataaatct agcttataga atgcaaggtt tctatgttgc taaaggaaat cctaaagaga
    14821 taacaacctg ggaggattta acaaaaccaa gtataaccat tgtaaatagg gaaaaaggtt
    14881 ctggaactag ggttttacta gatggtaaac ttagacttct aaactttaat ggtaaacata
    14941 taaaaggtta tgataatgaa gaattatcac atcttggagt tgcaagtact gtttctcgtg
    15001 gaatagcaga tgttggtttg ggaaatgaaa aagctgcttt acaagtaaat aatatcgact
    15061 ttattcctct tcacaaagag cgctatgatt tagttattaa aaaagaagac ttacaaaatc
    15121 cagtttacca aactataatt aacataataa actctcctga gtttaaagct gaacttcaag
    15181 gtcttggcgg atatgattta actgatactg gaaaaactat agcaaaagtt taagattaaa
    15241 atcgcaatct attttataag atttataatt tttcacaaaa tttataactt aaacacgaaa
    15301 taaattgcga ttttagtgtc tcaaaaaatt tatgtctttc attttatcat ccaatacaaa
    15361 atataatata attaattgtg caatcatatt atattaatat atatttacat aatagtattt
    15421 ttctttaatg tagattaaca tatgatatgt tttaaacatc aatccccttg ctttcttata
    15481 tatatttggc aacacatatg agtttaataa attatataca atgttgcttt cttcttgtat
    15541 tttttcaacc aacaagttat ttataaaatt acctttctca ttttcaataa tctcactcca
    15601 atttatctta acttttaata tatatcttcc cactaggtat acacactcta caataaataa
    15661 taaaaataca atgcagtcag tacctgttgt cttatataaa ttacccgata ctaatggctt
    15721 tgcgaagaaa ttataaaaat tcaaagtatc acccgtataa tcaaaaagta ttaatagcac
    15781 tcctagaact ctcaatactt taatattcaa catgttttta tctttattat ttttgttttt
    15841 catatatact acctctcttt tctttagatt tgattgtaat ctaatactaa ctcttttatt
    15901 tgaggtataa atgaatttaa ttggtagtta ttttcatttt tactagaaat taattcacat
    15961 tactaaacaa aacttatatt taaacataaa aatagcctat ctatttttta ataaatacaa
    16021 aaataaataa gctactaata ttcaattaac ttttatcact taaaacatta ctatctataa
    16081 atttaaatat tttattgaag tatactgtac tatcatgttc aaatccatca acatgaccaa
    16141 taccttctat aagccatagg tcttttttat catgtttaac taaatcatac attttcttgc
    16201 tattttgata attacaaaca gtatcttttg ttccatgtat aaacagtatg ggtacattag
    16261 atttctcaac tgactcatat ggttttacat cactgtacca aaatccagat ttaaacttat
    16321 tatataaatc tccacaagtc accacataat tgattaatat atctggtatt cgtttttcta
    16381 gtactcccat tctaattgca tctttcattt cagaataagg agaatccagt atataaaaat
    16441 cgaccttatc atcttttgaa tttatctctg aatgcatagc agctgtccct gcccccatgg
    16501 aaaatccatg cactcctaat cttccttcag gaaatttatt ttttacaaat ttaactagac
    16561 tatctaaatc atacctttca taaagaccaa atgtgtaatt atctccacca ctattaccag
    16621 tatttctttg attataaact aatacgttat aacctttatc taaatatcta tatgctacct
    16681 ttaacatttc atagtaacta cttccaattc catgaacaag tatcatagta tctcttgtct
    16741 ttatatttga agttataaaa agactttcaa gcttgtaatt attagaactt tgtatcatta
    16801 attcagatgt cttgtagttt tttaatttct ccagtggtct atcttttctc tcagaaaata
    16861 tttttactat atcttcgttt tttattaact gctctaaacc aactgaacta ttatacacta
    16921 atttgccaaa tatataagat acaattaata ggattaatag aaacacaatt gatataatta
    16981 taaatttatt tcttaaacta atacaatttt taaaactatt tttcatattt atttaccata
    17041 caattttcct atattatatt ttctaagtaa tagcataatt gatt
//
LOCUS       DAEHWO010000094        16909 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.094, whole genome shotgun sequence.
ACCESSION   DAEHWO010000094 DAEHWO010000000
VERSION     DAEHWO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16909
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.094"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..286
                     /locus_tag="KNP54_003367"
     CDS             <1..286
                     /locus_tag="KNP54_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBF0894228.1"
                     /translation="KDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFEKLEVYFVTN
                     TKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQLT"
     regulatory      379..471
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            571..1365
                     /gene="thiD"
                     /locus_tag="KNP54_003368"
     CDS             571..1365
                     /gene="thiD"
                     /locus_tag="KNP54_003368"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBF0894229.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            1389..2177
                     /gene="thiM"
                     /locus_tag="KNP54_003369"
     CDS             1389..2177
                     /gene="thiM"
                     /locus_tag="KNP54_003369"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBF0894230.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDALSKNSNIEFLN"
     gene            2200..2832
                     /gene="thiE"
                     /locus_tag="KNP54_003370"
     CDS             2200..2832
                     /gene="thiE"
                     /locus_tag="KNP54_003370"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBF0894231.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            2971..3273
                     /locus_tag="KNP54_003371"
     CDS             2971..3273
                     /locus_tag="KNP54_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0894232.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(3339..4094)
                     /locus_tag="KNP54_003372"
     CDS             complement(3339..4094)
                     /locus_tag="KNP54_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894233.1"
                     /translation="MGMLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMN
                     NININNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQL
                     LEAILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLP
                     NEIVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETI
                     LIGDIMPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(4082..5044)
                     /locus_tag="KNP54_003373"
     CDS             complement(4082..5044)
                     /locus_tag="KNP54_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894234.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(5048..5506)
                     /locus_tag="KNP54_003374"
     CDS             complement(5048..5506)
                     /locus_tag="KNP54_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBF0894235.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            5862..6218
                     /locus_tag="KNP54_003375"
     CDS             5862..6218
                     /locus_tag="KNP54_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0894236.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            6290..7006
                     /locus_tag="KNP54_003376"
     CDS             6290..7006
                     /locus_tag="KNP54_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894237.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            6999..7823
                     /locus_tag="KNP54_003377"
     CDS             6999..7823
                     /locus_tag="KNP54_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894238.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            7835..9034
                     /locus_tag="KNP54_003378"
     CDS             7835..9034
                     /locus_tag="KNP54_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894239.1"
                     /translation="MKLKSKISIFIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            9043..9855
                     /locus_tag="KNP54_003379"
     CDS             9043..9855
                     /locus_tag="KNP54_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894240.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            9866..11134
                     /locus_tag="KNP54_003380"
     CDS             9866..11134
                     /locus_tag="KNP54_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894241.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIIDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            11500..12681
                     /locus_tag="KNP54_003381"
     CDS             11500..12681
                     /locus_tag="KNP54_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBF0894242.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(12823..13740)
                     /locus_tag="KNP54_003382"
     CDS             complement(12823..13740)
                     /locus_tag="KNP54_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894243.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            13993..14787
                     /locus_tag="KNP54_003383"
     CDS             13993..14787
                     /locus_tag="KNP54_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894244.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            14788..16848
                     /locus_tag="KNP54_003384"
     CDS             14788..16848
                     /locus_tag="KNP54_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBF0894245.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         6675 a         1810 c         2713 g         5711 t
ORIGIN      
        1 taaagatgat tctctataca ctggatatac cagtaatata gttagaagaa tgaatgaaca
       61 taaattagga attaattcaa aatacacaag agcaaaggga tttgaaaaac tagaagttta
      121 ttttgtgacc aacacaaaaa gcaatgctat gaagttagaa tactatataa aaaaattaac
      181 tagaaataaa aaattgtcta taataaaaaa cccaagtata cttataaatt taattgataa
      241 taaagaagat tatattattg gtaaggaaat agaacaatta acataaatat ttatagtaac
      301 attataatgg gtgcatatgg tgtaaaaact tgacaataaa tactattgta atataatgaa
      361 gttataaata tagtaaatta aaatagctag gggagccaag agctgagagg tataccgacc
      421 cttacacctg atctggataa taccagcgta ggaaagctta gtaaaaattc aagtatgtat
      481 tatttgtgat atatgctatt tctaagctat acctattgta ggtatagctt ttttaattaa
      541 gttatttaaa ttaaacttta ggaggcaaca atgagtaatt ataaaatacc aacacttaca
      601 atagccggct ctgattcatc tggaggagct gggattcagg ctgatttgaa aacgtttagt
      661 gcaattggta cttatggtat gagtgtaata acagctataa cagcacagaa tactaaagga
      721 gtttttgctg tagaggattt aaataagaaa ataataaaaa aacaaataga ggcagtcttt
      781 gaagatatac ctccaagagc tgtaaaaata ggaatggttt caagtcctga gattatactt
      841 gaaatagttg agaatctaaa gaaatacaat ccaaaatatt tggttgtgga cccagtaatg
      901 atatctaaaa gtggatatta tctattaaag ccagaggcaa aagaaaactt aattaagtat
      961 ttgataccac ttgcatacat aattacacca aatataccag aggcagaaga aataacagga
     1021 ataaaaatac ataatgtaga tgatatgaag agagtaggag aagaaatact acaacttgga
     1081 cctaaatttg tacttatgaa aggaggtcat ttagatggag aagcagtgga tattttagtt
     1141 ggtaaaaata tatttaaagt ttataaaagt gaaagaattg ataaaaaaaa tacacatgga
     1201 acagggtgca cattatcttc tgcaataaca tcttatctag cattaggata tgaaataaca
     1261 gaagcagtaa atctaagtaa aatctatata acagaagcaa taaaaagaag ttttgatata
     1321 ggtcatggag taggaccagt acatcatttt tataaatttg agtaataaaa aaatattgga
     1381 ggtagaatat gtataattta attaaagatg taaaaaaatt aaatccattg gtaattcatt
     1441 atactaataa tgtaactata aatgattgtg ctaatgtaac tttagctgta ggagcaagtc
     1501 ctcttatgag tttttcatat gaggaagtag aagaaatggt aagtgtagca aactctgtag
     1561 taataaatat aggaactatg aactcaaata tgttggattt attcctatta gctggaaaag
     1621 cagcaaataa gtacaataaa cctgttgttt tggacccagt tggagtattt gcaagcaaag
     1681 cgagagcaga acttacaagt agacttttaa atgaagtcaa atttagtgtt gttaaaggga
     1741 atgtatcaga aataaagttt ataggtggct ttaatgtaag gggtaaaggt gtagattcat
     1801 ttgatgaaga agaagattct actgagataa taagaaagat tgctgaaaag cttgaatgtg
     1861 tagttgtagc aactggaaaa atagatataa taactaatgg taaaggtaca tataaaataa
     1921 acaatggaac tgataaatta aaaggaatta caggaactgg atgtatgact gctagcttga
     1981 ttgcaagttt tatggctgtt actgagaata tattagaagc agcaacaatg ggtgttctta
     2041 caatgtcttt aagtggggaa ttagctaatt taaataatcc accaataggt acatttaaag
     2101 aaaatcttat gaatgctatt tatcaaatgg atatagatgc tttaagtaaa aattctaata
     2161 ttgaattttt aaattaataa agagtaaggg agacttaaaa tgattgataa agaatcttta
     2221 aaaaaatgtt taaagttgta tttagtaact gactctgaaa tgcttaaagg tagagacttt
     2281 tataaatgtc ttgaagatgc aatatcttct ggaataacaa ctgtacaact tagagaaaaa
     2341 aatgcttctg gaagagagtt tttaagaaaa gctatgaaac ttagagaaat aactaaaaga
     2401 tatggtgtta agtttataat aaatgataga gtggatatag cacttatttg tgatgcagat
     2461 ggagtacatg taggacagag tgacattgat gttagagagg ttagaaagct tataggaaac
     2521 aataaaattc taggagtatc agcaagaact ttagaagaag ctatttgtgc aaaaaatgat
     2581 ggcgcagact atttaggtgt agggtctata ttcacaacat ctactaaatt agatgcaaaa
     2641 tcagcttcgt ttgaaactgt taaagaaatt aaagaaaaag tagacatgcc atttgtacta
     2701 attggaggta taaatttaga caatatagat aaacttaaat gtttagaaag tgacgggtat
     2761 gctataatat cagctatatt aaaagctgaa gatatctcta aagaagtgga aaagtggaca
     2821 ttaaaaatat aaaattggct ctggtagtga aaaaaatgga aaaatttgat ataatctaag
     2881 agtaaaattt aagcaattat aaatgataaa cttttctaca tatacttttt aatcaagata
     2941 tatgtagatt tggttaaaaa ggagctataa atgattagga tattgttagt gtgtgttgga
     3001 ggcatgtctt ctaccctatt ggtaaataaa atggagaagg atgcaaaaaa aagaaatata
     3061 gactgtaaaa tatgggcagt tggagaagga gatataaaat cggagcttga taactttgat
     3121 attttacttc ttggaccaca acttagattt atgcttgatg acgtaaagtc tatagttgga
     3181 gatagagctc cagtatctat aatagatatg gtaaactatg gcacttgtaa tggtcatgct
     3241 gtgttaaatt cggttttaga aatattaaaa taaataataa aagtggattc tatataatag
     3301 agtccatttt tattatttgt tattaatagg cttaaaactt agcttaccat ttcttttttt
     3361 aatctccaca tagcaagtga aaaacttgaa cagcacaata ttaaaaatag taggataaca
     3421 ggcattatat ctccaataag aatagtctca ccaaatatta agctacgtaa agcgttaata
     3481 acatgggtaa atggattgag catcactgct acttttaatc ctccagataa actttctata
     3541 gggaaaagag ctgaacttaa aaagaaaata ggaagtacaa ttgcagtcat aattgtttca
     3601 taaactattt catttggcaa taataaactt atagaataag ctagacttga taaaaagaag
     3661 gctgtcataa atatcagtac tatcataagt aggattccac caatgccaga ttctatcctt
     3721 actgagaaga atatacttac tatacacaaa atagttactt ctatgaaaga aactaagata
     3781 gcttctaata attgaccaag gacgattgaa tacctgctga taggtgcaat taagactcta
     3841 tagaaacttc cactgttctt cattataaag tttataatac caccactact acaagaagaa
     3901 aacacaacca gtacaatgat acctggtagt ataaaagcag tataattatt gatatttata
     3961 ttattcatag tttggtttgc aatagaacta taaagcacaa gccaaagaaa aggttgtaat
     4021 atagtaacta caaatgagat tggattttta aaacgccact tcatactacg ccataagata
     4081 tttaacattc ccattcctcc tttaagcttt ttttagaact tgtaagtgct aaaaatacat
     4141 cttcgagact tggctctaca atttctattg catcaaattc tatatcatgt tctaaaagcc
     4201 atttatttat taaagtaaaa gcagttctac tatcgtttac acttataaaa attgaatttt
     4261 ctcgtacgct cataaacttt actaaaccag tacttttaat tgaatcttta tattttttta
     4321 tatcttcagt attatgaaaa gttatacgta gtatattttg tctaatgtaa ctacgtaaac
     4381 ttgatggtgt tccttgtgct aaatcctttc cattcttcat aatacaaata ttatcactca
     4441 attgttcagc ttcttcaaga taatgagtag ttagaaatat agttgtgcca tactcatctc
     4501 taatttttaa taacatatcc cacatagatt ttcttgaatc gacatccata ccaacagttg
     4561 gttcatctaa aaataggatt ttaggagatg ataccatatt catagctatg tccaatctac
     4621 gttttacacc ccctgaatat gatgaagtag gatattttaa gtaactagat aagtcaaact
     4681 tatcaattaa agagtctatt ctttgttttg caatctgtgg ttctacttta tacattttac
     4741 tttgaaatac catattttcc ataagggata aatgttcatc aatagagatt tgctgtgcta
     4801 cacaagcaat ttgagtacgt atccaagaag gattatctac taaatctttt ccaaacattg
     4861 ttacatttcc agatgtaggt ttgtaaaagg tagtcaaaat atttataaga gaagatttac
     4921 cagcaccatt aggaccaagt aaagaaaaaa tttctccagc atttacatta aagcttagac
     4981 catttaaagc tttcacacca tttttatatt cttttactaa attgtctatt tcaatcgcta
     5041 acatatatta ttcctcctct ttaagtggaa atattatctc tgtaatatag ttatctgggt
     5101 ttccttttat caacatacct ggtcctttaa taaatacttc tctccaagga gtttgtattt
     5161 ttatattatt ttcatgaata tatttaaata tcatttcata cgtttttggc aaattactat
     5221 aagagcctgt gtgagtaaaa aataaagctt ttgttttagg aaattctttt gtagttatac
     5281 ccatacgatt tggagtttca gcagttggaa cacataattc catttctgca acaccagttt
     5341 tttggtcaac atcatagtag caaaagaatg gtgcaccgtt agactttcct tttatagctt
     5401 taaatacatt tggaaaatac tttgttgcct cagtcatagg tccattataa cgcatggtag
     5461 ccactgtgac tgattcgata tttttgattt caattttgca attcatttgt ttacctccta
     5521 atgtgtgttc atattcttac tagattttta agcattaata catataagat tttgattagt
     5581 tgaaaacata taatcttatc tcgtttgctt gttttcaagt ctaacataac ataaaatata
     5641 tatcctctca tttgatgctc cattttgtaa agttattatt taagctttac tttagatttt
     5701 ttagcaaatt aaaataaagc aatttataaa ataagtattt acaaattaag tgtattaatc
     5761 gtataataca cttaatagga tactagataa agtctgaaat aaaggcgtat ttttttaaag
     5821 taagtgtact atcgtattaa tacactagaa taggaggaat catgaatttt gaattagata
     5881 atacaactcc catttatttg caaatagtaa agtatataaa gagacaaata gtaacaggag
     5941 agttgaaacc aggagagaca ataccatcaa gaagagaaat ggcacttaat ctaaaagtaa
     6001 acttaaatac agttcaaaga gcatataagg agatgggtga tatgaatata ataaatactt
     6061 ttaaaaatta tcaaagcagt gtaacagttg atgaaaatat attaaaaaat ttaaaattag
     6121 agcttataaa tgaatcacta tctgttttta tagaagatat gaaagcaata aatgttagca
     6181 aagaagaagt tttaaaaata atagaagata agtattagtt ttttaacaaa tagaaaactt
     6241 agtttagaaa gtttatttat aagcatattg gatgtggagg atagtaaata tgatagaaat
     6301 aaagaatgtc agcaaaacat ataaaaggat gcaagggctt aaaataagaa agatagaagc
     6361 tttaaaaaat gtaagtttta atatagaaaa gggaaaaata actgcattac ttggtataaa
     6421 tggtgttggt aaatcaacta tgttaaaagc aatagcagga cttataaaca ttgatagtgg
     6481 agaaattcgt atagatggag aaaaaataaa tgaaaaggta tacaataaat tggcttttgt
     6541 tccagatgta caatctcact ttagcaatac aacaataaaa gaaacatttg aatttatgga
     6601 aattttttat tcaaagtgga ataaagaaaa atcaaaagaa atgatggaca tatttaaatt
     6661 ggatgaagat gaaataattg ataacttgtc aaaaggaaac attgcaagag taaaattaat
     6721 acttggattt tgccaagacc cagagtacat acttcttgat gaaccattta caggaattga
     6781 tttgtttaag agggaagagt ttataggagt aatagcgcaa tatatggagg aaaatcaagc
     6841 cattattata actactcatg agatagtaga gatagaaagt ttagttgatg aggttgtaat
     6901 tcttgatgaa gggcagatta taacttcatt taatgcagaa gaattaagag aaagagaagg
     6961 taaatctata ttagataaga tgagggaggt atataagaat gaataaactt ctatatctaa
     7021 taaatgtaga tttgagaaga agcaataagt tttatatagc ttatatatca tttttttcat
     7081 taattacact tagtttaaat ttattcgaaa ttaataaatt taaaaattct aaatttatta
     7141 tgaacttagc aatagaagat tttggaggta tattttatgg actagggata cttagtaatc
     7201 ttggttttat ccaaagtata ttgttctttg ggatattggg actttttata tactatattt
     7261 ttatgtggaa aagagagttc ttttcaaata atcaaagtat ttatacactt atgatgttac
     7321 ctcaaaataa gtttaagatt tgtatatcta aatcaatagc cttgataaca atgatatatg
     7381 gttttttgat aagtcagaca gcaacattat ttatatgtaa atatatattt aatttcattt
     7441 ttagaaatat gcctataatc aatatgaact ttgccaaaga tttatattat ttaaacttga
     7501 agagtatacc aattgatttt atctctttta tggctattta tgtattttta ctacttatag
     7561 ctatttctat tgtaaattgc tgtatattat ttatcttttc ctatataaat aaattttatg
     7621 taattttaat cactttgctg attatagcag gcttatattt ttcaacaata tatataaata
     7681 taatcacttt atttagaaaa tattataatc ttataggatt tcaatttaac aatttagtag
     7741 cagggttatt aagtttttta attataatgt ttattctaaa tggaatatct tatttgctaa
     7801 ttaaaaagaa agtatctctt taaggagggg tggtatgaaa ttaaaatcta aaatatctat
     7861 atttattata tttttgactt tagcaatata ttttagtata ggtttattaa ataatgaaga
     7921 taatttaaag ataaaaacta taaaaggtga ctctaatgaa ttagaccata taaacataaa
     7981 ttttggatat gctttgaatg gatatataaa ttcatattat acaataaatg gaagcaacaa
     8041 aaccaaaaag actgaattaa taaaactaca aaaggatagt aagaacacaa ataatttaat
     8101 tgatgtatct agtggttcag atttaattgc tcatgttgga tttgaaatga atgaggagtc
     8161 aaaagatata aactttgtga tagatgagaa aaaagaagat ttagaaaaag gtgtatttcc
     8221 atcagaaggt agtgataaag aaattgaata tgaaaaatta gatatgaata attttacaag
     8281 gacaagatat aaagtagata aaagtacaga tgattattat gcaaagatac tagcatcaaa
     8341 aagatataaa aaatacttat atgtatctgt actttatgct acaagtgatt catcagaaaa
     8401 taacaaagaa tattcaagta ctatagatat aataaaaatt aatccagaaa ataaaaaaat
     8461 caagactata aaaagtataa atttaagtaa ttatttttcc gaaaaatacc aaaacataga
     8521 gaacataggt gtaagttatg ctagcaaata tgaggataag atgtatattt tagtaaatgt
     8581 actaaataca aacataggtg ataatagtaa ttctaaattt catttacttg agtataatct
     8641 tgaagaaaat aaggaaagca taatggaatt aaaaactgat agcaaaatgg ctttagcaaa
     8701 agcaaagtta gaagctaata aattatatat ggtaatgtcg aatgattatg ataatagttc
     8761 aattacagag ttaaatttac ttacctataa tatattagat aaaagcttag atgaagataa
     8821 atatgtttta gataatagag aaaaaagagg aattagaagt attgaaattg attcaaataa
     8881 aatcgttgca tatacatcaa ggctaaactc tatattatct tgggatgata aatttatgct
     8941 atatataata aataaaaatt ctaaggaaat tgtatatgaa ggagaattac aatttaacag
     9001 ttcaaatagt atgttagaat ttgaaataaa gtaggtgagt tgatgaaaga tttaataaga
     9061 ttattcgaat ttgaattaaa aagaaatata aagaattata tatttataat aatttgttgt
     9121 tgttcttttg taattttaaa catagtaaaa aatttaaatg actataatta cataatagaa
     9181 aatgcagtta aaagtgaaca gttaacaaaa atcggaaata cgatagaaac ggtaaatgtt
     9241 acaggtttct caagctttag aaatataatg ggttctacag aatcgtggtt tatgtttggt
     9301 ataattgcat gtatttgcta tgcttttttt atttggtata gagactttaa tggtagaagt
     9361 aaatctatat atacacttat aatgctacct aaaaatagaa tcaatattta tatatctaaa
     9421 ttattaaata tattatttct agtgtatagc tatacagtag tacttacaat atctttgttt
     9481 attgcaagta agttgttgcc tagacatatg cttggtaatg tcacaaacta tggttttgta
     9541 caagaaacaa tatatgagtt aaaaatgtta cttccatata gctttgaaat actatttgta
     9601 gagtatatat ttttattgat aggatttgta tctgtagtat ttacatcaat tcttataaat
     9661 aaatctattt ataaagtaag cactttaata agttttctat ttttagttat agaaatttta
     9721 gtgtttataa tttctataga atttattata ccttacgaat acagtgatgt atttactgtt
     9781 ctatattcaa gtataaacat atttgtatgt agtcttatat ctaataaact tttgaagcaa
     9841 aagattgact tttaggaggg atattatgaa agcaaaaaat ataggaaaat atacaatatg
     9901 ttttataata gtatgttttt taatgattac tatgacctta atattgagtt attttaataa
     9961 ggataaacta tctgtaaaaa ctttaaaagg caatgtaaaa gatataggga gagtaagtgt
    10021 agtatataca cctaatataa gcaaattttc ttatgaggag gtaattataa gtaaaaatgg
    10081 agtaagaaat aatacaaacc caaaatcaag aattagaaat gattatttaa atattgacaa
    10141 aaaatacagt gactttgtta atgataaagg aaaagaattt atatataaag atgatttgaa
    10201 tataggagaa gcgtatacct ctgttaagtc tgatttagta caaggaatga atgctttaaa
    10261 tgattgtata aaggtttcaa ataaaaattt aaaaagtggg gtagaagaaa attttgatat
    10321 taatttaaat aagtctgatt ttaaagaaaa tagttggaaa accttattta acaaaatata
    10381 taaaggtaat ttatatatgg taattagtga aactaatatt tcaggttcta aagtcaataa
    10441 tatttgtata ttaaagatag atataaaaaa taagtcttat aaattattaa atagatttaa
    10501 tttaggatta cagaatggag aacaacaaaa tatcaatgaa attaaatttt ctattggaag
    10561 taaattatac ttagaaatag taaataataa aagtaaaaat ggatatattg aaggacatga
    10621 tagttactct aactttatta tatatgatat agaagataac acttttaata taagtaataa
    10681 atttatggat aatctaaaca aagaaaagaa tgcaaatcca aaggagattg gcttattaag
    10741 taaaactaag ctagattata tggtaaaaaa caataaattg aatcttatag ttacggatat
    10801 gagtaattcc ataactaatc ttgtttatga tattaattct aatgagatta aattagaaga
    10861 ttatgagata cttgatttaa aagtagatta taatgaagca tcatctggag ttaggaaagt
    10921 taagctactg gatgataaga tatattctat ttcaggtatt aagaacagta tatcaggaga
    10981 attaaaagga tttaaaggga ttattgatgt agtcggaact aagccagtaa aatttcaagt
    11041 atttgatatg aaacttaaaa agaatattta tgaagctgag ctaataaatg gagatataag
    11101 tttacaagaa aagttatttt ttgttgcaaa ttaagtgtta gaattaattt tagaacttta
    11161 aacttttata tgtatcacag ataagtataa gtaagggagt gtctcaaaat aaacttttta
    11221 gctcatgaga cacttttttt atatgaaatc aaatatattt tcattgttta gatttatttt
    11281 gataatgaaa aaaagattat ctttatttta agaaagacat ttatttataa ttatatacaa
    11341 aaatattttt taatgttttt gtgtataatt ataacaattt aatttatatt aatgcactta
    11401 aatttgaaat agaatgctta tagtggtaaa attaattatt agaatattag aaataataaa
    11461 taaataatac attgtactta aaagggggag aaatttaaga tgaacaaaaa atatattaaa
    11521 gcagggaatt taattgatgg aaccggaaat agtattatgc aaaataaggg tataattatt
    11581 gatggagata ctatagttga aattgaagat ataagagatg atttaaatgg atatgatgtg
    11641 tacgattact tagataaaac tgttatgcca ggcattatga attgtcatgt tcacttgaca
    11701 atggagccag ttggaaatcc aaagatatat tatgataatg tatcagatgt agagcttgta
    11761 gtaaatacga taaaacaact tgatgcttat ttggattcag gagtaacata tattagaagc
    11821 ttaggttgtc ccaaatatgt ggatgtacaa cttaaaaatc ttatagacaa agggtctata
    11881 gatggtcctg gtatagttac ttcaggtcca gttatatgta tgacaggagg gcatggatat
    11941 tattttggta ttgaaagtga tggagtagat gaatgtagaa aatcagccag aacagtttta
    12001 aaaaatggag tagattgtgt aaagataatg gcaactggag gtgtaacaac tgatggagtt
    12061 gagccagggt caccacaatt aactttggag gaaatgaagg ctgctgtaga tgaagctata
    12121 aaagcaggta aaataactgc cacacatgca caaggaagaa ctggtataaa aaatgcagtg
    12181 cttgcaggaa ttacttctat agaacatggt gtttatttag atgatgaaat aattgatttg
    12241 atgcttgaaa gaggaactta cttagttcca actgtggctg caccatattt tattctaaat
    12301 gcaggaaaag aaagtggaat aactgaagct actcttagaa agtgtgagat tgttgccatt
    12361 ccacacaaag agtcattcct aaaagcatat aaaaaaggaa ttaaaattgc agttggttct
    12421 gatgcaggaa cttcttataa tgaacatgga aaaacatatt atgaaatgaa actaatgtca
    12481 gattatggta tggataatat ggatataata gttgctgcta caaaaacagc atctgaactt
    12541 ttaagaattg ataaaaatta tggaactcta gaaaaaggaa agaaagcaga tgttatagtt
    12601 gtaaatggaa atccagtaga gaatatagac gtacttgcag atgtgttagc agtatttaaa
    12661 cttggtaaaa aagttagata aatagtataa aaataaaaaa gagtgtctaa agaaattttt
    12721 aaataattat agacactctt ttttattagt aataattaaa tcttttatac tttagaaaat
    12781 agattctatt ttatatttag atataactct ttaaaatcat tcttatgcaa tataatctat
    12841 agaatctaca catacaaagt atattcttga atcattagaa tttccaagta ctataacatc
    12901 atttttctta cctagaactt caacaccagt tagaaccaaa ctaccagcta ctacagtaac
    12961 ttgattattt atatttgaca tataaagatt atctaggata cctttattac aacagcaatc
    13021 atcacaatcg cagttgcaat tacattcttt gtaatgtttt ttatcaagat agtaacctaa
    13081 agatgctatg aaatcttcat aatctgcagg tgtaatatca aatgcaacag ctttaagatt
    13141 acacaatgat gctaaatcta cgtttgctaa tggagtagat gcagcaagta taaaatcaat
    13201 tatagcagca agtattgcat ctaatatagc cccaaggtct atcgtaggag gaataactgc
    13261 atcaataagt gcaattaatt cagctactcc tggtatagtt cctatagtat taattaatcc
    13321 ctcaagagtt aaagggactg gaataggata agatactcta ccagctatat ctattaaatc
    13381 acagttacaa gcagaaaatc tttcaaaagt accatcaagt ccagataaat tatcttttgg
    13441 aggagctgaa agatctatac ctaccaaatt agcacctact ataaagaaat ctgagataaa
    13501 agcaaattga ttaaagttta caaaaggtct tagagcatca tatcttagaa gttctaatgc
    13561 ttctctcata ctttttttac aacaacattg ttttatttta ggttctttat atttatttgg
    13621 ataattatag tatctatcag ctacttgata attttcatag tatctttcat ttgtatttgg
    13681 ataatcttcc tcatattctt gtgtaaatct aaagtcctct ctacatttat tattttccac
    13741 taaatacact ccttttatat tttaatttaa atgtatagat aattaagctt atctatatag
    13801 taatattata tttataatgt aaaaaaatgt tacaaaagat attataaacg aataaaaaat
    13861 aataatttgt cagataaact tgtaaatttt tatgaataat ccattctaaa acaaaaaact
    13921 gtgtataaaa aaggtttata tgttatattt atataaatat aacatatgaa cgagaaagga
    13981 gtggtttgat aaatgattga ggtagataaa ttgtgtaagt cttttacaag ggttgtaaaa
    14041 gatgataaga ataaaagttc aataagaaag ctaaagaaag taaaaactaa aaaagaagaa
    14101 ttttttgctg taaataatgt ttcatttaaa gttatggaag gtgaaattgt tggaatatta
    14161 ggtccaaatg gtgcaggaaa gactacatta cttagaatgt taggtggcat attaacacca
    14221 acatcaggaa gtataaatat ttctggatat gattattcaa tagatagaaa ttcagcaaaa
    14281 aaagaaatag gttatctctc tggaaataca aaactatatg gaaggctttc tccgagagaa
    14341 cttctaacaa cttttgcaag tctatatgag atgtcaaaag aagatataga agaatcaatt
    14401 gaaaatattg taaaaataat ggatatgagt gaatttatag ataatagaat tgaaaatcta
    14461 tcaactggtc agactcaaag aacatctata gctcgttgtt taatacattc tccaaaagta
    14521 tatatttttg atgagccaac actaggtctg gatgttttaa gtagtgcatc tattatagat
    14581 tttatgaaga atgaaaaact aaggggaaaa actgttcttt actcaactca ttatatggaa
    14641 gaagcagaaa ctttatgtga caagattttt atgattcaca atgggaaaat aattgcatca
    14701 ggaacaccac agagtttaaa agaggaatct ggagtaaata atttgagaga tgtattcata
    14761 aaacttgcca gaaaggagga catttaaatg agaagtaaga ttgtaaaata catatttaaa
    14821 aaagaaatgt tagacatatt gagagataaa aagactttat ttatgatgat tgttgtgcca
    14881 cttcttttat atcctttact tatgttatta atgattcaag taatgaatat gtctgcaagt
    14941 agtatgaata gtaaggacat taatatagct tttaataata aacctaataa ggtgttagta
    15001 tccatgattg aagatgataa tttagaaaaa gatactaaaa atacttcaaa tgataaaggc
    15061 aaaataagag tgttagatgt agataactat aaaaagtcat tagaagaaaa taaaattgat
    15121 gcttatataa agatggaaga aaaaaaatca tctataaatt atcaaatata tataaattct
    15181 tctcaagaaa attcttctaa tgcactaaaa agaattgaaa ctgttttgga taaatataaa
    15241 agatttacca tagaaaaaac tttatctgaa aaaggattag atgtacaagc tactttagaa
    15301 ccaataacat atagcactgt agatgttgca aagacggaag aagtggcagg atacttttta
    15361 ggtcagatac ttccatttat attaataata ggagttttac taggttcaat atatccagca
    15421 atagatgtta tggctggaga aaaggaaaga ggtacattag aaacattatt tacactgcca
    15481 atatcaaact tagaactggt tatgggaaaa tatatggcag tttctcttag tgcaatagta
    15541 acagcaattt taaacatttt atctatggga ctgactatgg catttatttt agttagtgga
    15601 ggtattagta gccaatttgg ctttggaaac tttaattatg gagacttagt cttaccaatt
    15661 ataactactt taatttgcat atgtcttttt tcaatggtag tttcagcaat aagtatgtgt
    15721 gtatgttcat tagcaaaaag ttttaaagat gctcaaaact acataacacc tcttatgtta
    15781 attattatga taccatcata tgtttctatg ataccaaata tagtattaga tagagtgaca
    15841 gctgtaatac ctgtagtaaa tatatcttta cttataaaaa gtgtattatc ttttaaaagc
    15901 gatttaaatt taatagcctt agttttagca tcaaatgtag cctttgttat attggcaatc
    15961 atactactgt ctaagatgtt caattctgag gaaatacttt ttggtaatag taagagtttt
    16021 tctttcttag agaaaagaag taatataaaa aaagggtcta taccaactgt aagtgatggt
    16081 gttattttat atgcagtagg attagttcta ttgatttatg ttggttcttt agttcaaatt
    16141 aaatttggta tggcaggtat tataatgaca caattcatga taatttcttt accattatta
    16201 tttgcatact atattaaagc tgattttaaa gaggtattta gcttgacagt tcctaaatta
    16261 aagcatgtgt ttgggagcat tgttctttgg attggtggat acatacttat tatgattata
    16321 acacagctaa ttttattctt atttcctcaa aatatggaag ttgctgaaag tttaaataag
    16381 gctcttttta tcaaagatag tgttttactg aatttactag caatagcttt attaccagct
    16441 atatgtgaag aaatgttttt taggggattt atattttctt catttagtaa atcaaaagat
    16501 aaaaataagt ctatcaaact cgctataata tgtagtgggg tactatttgg tattatgcat
    16561 atggatttta ttagaataat tccaacatca atattaggta ttatatttgc atacagtgtg
    16621 tataaatctg gttcaatatt tgtatcaatg ttattgcatt ttttaaataa tagtgtagca
    16681 gttgtgttaa atcattatac aactggaaat ataaccaact tatataaatt tgttgaagtt
    16741 gatttttcga acttaaatgt gcttaaattt gccttaattc ttctaataag tcttatatta
    16801 attatgttag gattaagagt tttagataga aagtctttaa gaaattaagt ataaagttat
    16861 tatatagatt aaaatattaa taagcactaa agtatatgga tatatcttg
//
LOCUS       DAEHWO010000095        16656 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEHWO010000095 DAEHWO010000000
VERSION     DAEHWO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16656
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.095"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            276..2135
                     /locus_tag="KNP54_003385"
     CDS             276..2135
                     /locus_tag="KNP54_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBF0894246.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2427..3026)
                     /locus_tag="KNP54_003386"
     CDS             complement(2427..3026)
                     /locus_tag="KNP54_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBF0894247.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3129..3926)
                     /locus_tag="KNP54_003387"
     CDS             complement(3129..3926)
                     /locus_tag="KNP54_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBF0894248.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(4039..4144)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4236..5222)
                     /locus_tag="KNP54_003388"
     CDS             complement(4236..5222)
                     /locus_tag="KNP54_003388"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBF0894249.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5706..7436
                     /locus_tag="KNP54_003389"
     CDS             5706..7436
                     /locus_tag="KNP54_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBF0894250.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLSIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7546..7626
                     /locus_tag="KNP54_003390"
     tRNA            7546..7626
                     /locus_tag="KNP54_003390"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7580..7582,aa:Leu,seq:tag)
     gene            7961..8476
                     /locus_tag="KNP54_003391"
     CDS             7961..8476
                     /locus_tag="KNP54_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBF0894251.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8968..9072
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9282..11756
                     /gene="gcvPA"
                     /locus_tag="KNP54_003392"
     CDS             9282..11756
                     /gene="gcvPA"
                     /locus_tag="KNP54_003392"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBF0894252.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11756..13213
                     /gene="gcvPB"
                     /locus_tag="KNP54_003393"
     CDS             11756..13213
                     /gene="gcvPB"
                     /locus_tag="KNP54_003393"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBF0894253.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13636..15993
                     /locus_tag="KNP54_003394"
     CDS             13636..15993
                     /locus_tag="KNP54_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBF0894254.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(16079..16396)
                     /locus_tag="KNP54_003395"
     CDS             complement(16079..16396)
                     /locus_tag="KNP54_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBF0894255.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         6306 a         1924 c         2712 g         5714 t
ORIGIN      
        1 tataataata tataattata atgatataat tttaataggt ggtttgtaat taaaaagttt
       61 ataaattata ttaatagtaa taatctataa gaacttatat attagaaaaa aatttttgta
      121 tatataaagg actctaaaga tgaactatgt aaaacaaggt ttatatattc taattgtata
      181 gaaaaattta ttgtaaacgc atgtatatta ttagaaaaaa tagtttggag gtattcaata
      241 aacataaaaa acaatatagg ggataaaggt gttttatgaa gagatttttg aggagaatta
      301 tcttagtttt atttattttg ttgattttta taagttttat ttctattaaa ttaattcata
      361 atgttggaga ttatggaaaa ttgattaatt atgttgggat tgttcgtgga gctagccaac
      421 gtctaactaa actagagatg aatcatcaac caaatgatga attaatagaa tatattgatg
      481 aaatcctaca ggagttgatt acagggcatg gagattatgg tttagtaatc actgattgta
      541 atgaatacaa tgaggactta cttttattag aaaaaaagtg ggaagattta aatattgaaa
      601 ttaaaaaagt aagaatgaaa gaacagaata accagttatt aagtataagt gaagagtttt
      661 tttctcttgc aaatgataca gtgtttaaaa tagaaaactt ttctaaagaa aaaagtaatt
      721 acttaatgac tttaataata attatatcta ttataggtat attagcatgt atcatattga
      781 ttttacaata tagtaaaaaa atggttagac tggaaaaatt aaatgtagat ttaaaaaata
      841 ttgcatataa agatgaacta acaggagtaa atactataga aaaatttaaa ttggatgcaa
      901 atcaaaatat ttgtatacat aaggataaga aatttgctgt attctatatt gattttgaaa
      961 actttaaata cattaatgat atatttggat atgattatgg tgacatgata ctgaaaagat
     1021 atgctaatct tatgatgaat gacataggga aatatgaaat atttgcaaga gaaattgcag
     1081 atagatttgt tgcgttaaga tgctatgtag ataaggaaga tttagtggta agacaacgag
     1141 atgtagacaa tgaactaatt aatataacaa atgaaattaa aaataaacat agtattactg
     1201 ttgttagtgg aatttgttgt attgaagatg taaatgaaaa attaagtata gatggtttaa
     1261 taaatagagc aaattttgca caaaaaactg ttaagaataa accaggtact aattatgctt
     1321 tttataatga cagtattcgt aaaaaaatga ttgaagaaaa tactatcaaa agtagaatac
     1381 atgaagctat tgaaaaaaga gaatttatag tttatttaca gcctaaagtt aatttacata
     1441 gtcaaaaaat aaattgtgca gaagctttag ttcgttggct tactccggat aaaggtatta
     1501 tatctccagc aatatttatt ccagtacttg agaagaattt ttttattgcc ttagtagata
     1561 agtatgtttt tgaggaggtt tgtaaatgga ttagaaagag gttagatgaa aataaacctt
     1621 ttgttcagat atcagttaat gtttcaagaa tacaatttta taacactaaa tttgtagaaa
     1681 cttattccaa tatacaaaat aaatacagga tacctaaaaa tactatagaa attgaattta
     1741 cagagagtgt tgcttttgag aatcaaaaac atcttttgga aattatacat gatttgcatg
     1801 aaaatggatt tacttgttct ttagatgatt ttggaaaagg ttattcgtct ttaagtgttt
     1861 taaaagattt accatttgat gttttaaagc ttgattctat gtttttcaag gctagtttag
     1921 ataaagataa agagaaaata gtaataaaaa atattgtaca tatgttaaaa gaacttaata
     1981 tcacaactgt tgctgagggc attgaatgca aggaacaagt tgaatttctt agggatattg
     2041 ggtgtgattt agttcaggga tttgtatttt ataaaccaat gccaatatta gaatttgaaa
     2101 aaatattgga taaagagttt gtttataata gctaaaatgt actttataaa atatgaacta
     2161 attaagtaaa attattttgt actgaataaa tttttacttt atttacagaa taatgattat
     2221 ttacagaaaa gcgcgaaaag tgtattcctt taagtgtggg atggatagca caaatagagg
     2281 agaaaaaata ttggccatat aagaatgcat aataatataa atatttaaaa ggtcagcatt
     2341 atataaaaat taaaaagaaa ataaataatt tttctataaa aaagagacta tgagaaaatt
     2401 tactcatagt ctcctaaata atgtatttat tttcttcctg caacccattt taatccccaa
     2461 tgaaattcag tatccatttc tctatgacct ttgaagtatt taactacttt ttcaacactg
     2521 aatgtctcat catttacatt ttctatcaat gctattgaac acatattata gccattttta
     2581 tgttcatcaa gtttgacaac taagtctgaa tcttgttttt gtttgattgt tacaattcca
     2641 tcagcttcag accagttagc tacaccttcg tatataaaag cataaataag tattcttttt
     2701 atatctttta ttttattacc atttattctt aaattttctc cttgtgtatt acttcctgtt
     2761 ctgtcatctc catctaattg agcaaaaggt ggattgtcta aactaccaaa ggcatttcct
     2821 aatgcttgaa cagcaccttt tacaccattt ttcatctcaa ataggcaacc caaatctaaa
     2881 tctatattac tgcttcttaa agagccaaaa aaaccctttt tttgtacttt ttgattccaa
     2941 tttaaattaa ctaaaatttc acctaaatcg ctattttcct tttttgtaag gtttattttt
     3001 tgtccctttt ttaattctat agccatagta atcttcctcc acaaacatag atttatttaa
     3061 atggtagcac ttaataagtc aatattcaac aagattagaa taataatatt aaaattatac
     3121 taaatatact aaaaagtagg aatcacaata cctttgtatt tttcttcaat taagcttctt
     3181 gctttatctg atgtaagaac atcttgtaga actttaatct tttcactgtc tttatcttca
     3241 gttctaaatg ctaaaagatt tgcatactcg tcatttatag gagctgtata aattccgttt
     3301 ttcttggcat caagaccagc aggtacagca taagtagtat ctataaatgc agcagtcaca
     3361 tctggaagag aagatggaat ttgagcaata tctaactctt tgaattgtat tccctttgga
     3421 ttttctatta tgtccttagg actaactaat ccatcccctt taggtaacgt taaaagtcca
     3481 atactttcaa ggtatctaag gttcttagaa caagaagatg ggttattgct tattgcaatt
     3541 gtatctcctt ttttaaattc atcaacagat tttatcttat aagagtaaag tattgctggg
     3601 catacatata gttttttacc agccattatt ttgtaacctt tggccttaac agcttctttt
     3661 agataaggtt catgttgaaa tagatttgca tcaatttcac cattatttaa agcttcgttt
     3721 ggaagtatgt aatcatcaaa gtttttaact tctaaagtat atcctttttc tttaataagt
     3781 ggttttaatt cttctaataa ctctcctcct ggaactaaag tagcaccaac aacaattttt
     3841 ttatcatctt tagctttaga acatccaacc acagctaaag ttagtactag acataataac
     3901 aaacataata attttttgaa tttcatataa attccctcct gaatataatt gattagttaa
     3961 aaataaaata ccattcttta tcacactgca aaataaaaat aagcctgagt ttaaactcag
     4021 gctttaaaag ctaatttaga ctcatctttc agtataatac tgcaggattt agcaccaatg
     4081 tatataaaaa tatactggtt gctgggtttc atagggccag tcccttcacc actctggata
     4141 agaagtatca atttttaatt atgttataaa tattatcatg attttttacg tctgtaaaca
     4201 taattttata aatattttaa aatctttaat gtattttatt taacacctaa aattccagaa
     4261 actagaatat cagtatcagc acctaagaaa tagtcattta tttcaataga atccagagta
     4321 tttctcaaag cattttcttc atgccttata ccaataagtt tattttctac aaatgcaaca
     4381 tcacattttc caaaaaaatc tccaaaaaat tttatactag ttattatgcc tttatcaaca
     4441 tttaaattaa actcaacatt tccaccagaa tattttaatt catttgaaag agtatatttt
     4501 ggtgaattac caaaattcca atcccaagtt tcgtattttg atttagtaag cttttctatt
     4561 tgttttatat catgctcact caaacaataa ttagtattat cagtatttgt tttagaaaga
     4621 taatccatta tagcatcttt aaattctaat atgtccattt ttgaatgtaa atgttcactt
     4681 atattggtta cacgagattt tacagatttt attccttttc cttcaaattt tataggttta
     4741 acctttaatg cttttgagag gtcatttatt tcagatgaaa ataaaagagt cccatgatgc
     4801 attactttgt ttttgtagtt gtattgagca tttccagaaa atttcttgcc atctataaga
     4861 aggtcatttc ttccagaaaa ttcggcattg acatctagtg ttttaagtaa atctattatg
     4921 ggctgagtga atcttctgaa atcactaaaa ttattattgt tacaagctat aaatgtaaaa
     4981 tttatatttc ccaaatcatg aaatacagct ccaccaccag actgtctcct aacgacaggt
     5041 atagaatatt cttttatata ttctaaattt atttcagaaa gtgtgttttg gttttttcca
     5101 acaattatag aaggttcatt cctccataaa ataaataagt cttcatcaaa attttttaga
     5161 agatattctt ccattgctaa attaaaataa gggtttgttt tttcattata aattaataac
     5221 attaaagtag ttcctccata gaattgataa aatttttatt atgaatacaa ttaattttat
     5281 aattcgacaa taatataaaa actcctttaa attagaaatt ttaaaaacta ccttgcaaag
     5341 tttaaataaa taatatatac tcaaaatatg tttaataaaa gtgaatagaa gggtagaggc
     5401 gcaataatct atcagtacta ataaggagtt aagcacagag agttattagg aaaggagata
     5461 ttgccgaagt tttataatcg atgctttaag attatattgc tgggggtaca tagaaaatat
     5521 gtacaactgt cacaggttta tttgtggtga gctatcattt aaggaattat attatattta
     5581 tttttactat tgttgatata ttgtaatgtt taagccttga gtgtttacca ctcaaggctt
     5641 ttttagtttt attgtaacat aataccctgt acagttcaca aaattaaaag gagagggaga
     5701 tttatatgag gaacaaaaaa attaatatta tttttctgac gacaatcatg ttcataatgt
     5761 caacagtaat ggtttttgca gaagaagata tagacactat tgcactagcc aatgcagaaa
     5821 aatttgggat tttaacttta ataccaccat tagttgctat aatactcgca tttataacta
     5881 aaaacgtaat aatttcttta cttataggta ttctttctgg tagttttata attaaagcta
     5941 gtggtattaa tgtttttgcg acatttatac aggcattttt agatttagta gatagagctt
     6001 tagtatcttt agcagaccct tggaatgcgg ggataatact acaggttttg tcaattggag
     6061 gagtaataaa tcttgttgct aaaatgggag gagctaaagc tatagctgaa gcacttgcta
     6121 aaagagcaaa gtcagcaaaa gggacacagc ttataacatg gtttttgggg cttttagtat
     6181 tctttgatga ttatgccaat tcactaatag taggtcctat gatgagacct gttgcagata
     6241 aaatgaaaat atcgagagaa aagctagcat ttataataga tgccacagca gcaccagttg
     6301 ctggtttagc tataatatct acatggatag gtcttgaggt tggtttaata catgatgctt
     6361 ttgaaagtat aagtatagat gtagatgcat ttggtatatt tttaaataca ataccattta
     6421 gattttacaa tatattaata ttagctttca ttgtaatatc agcattatta ttaaaagaat
     6481 ttggtccaat gagaaaagct gagataaaat ctagaagtag aaaaattagt atagaccttg
     6541 atgaaggcgt agaagagttg gatgatttag ctccaaaaaa tggagtaaaa ttgagtgtat
     6601 ggaatgctat aatcccaata ggaacattga taatagttgc attagcatca ttttattata
     6661 gtggatatac atctataatg ggaggagacg ataaggctct gatacaacta tttacaaatt
     6721 ctccatattc ttttgaagca ataaaagaag catttagtgc atctgatgca tctagagcat
     6781 tattccagtc tgcacttgtt gcaagtttag ttgctattat aatggctgta gtaaaaaaga
     6841 tttttacaat atcagaagca attgatgttt ggatagatgg aatgaaaagt ttagtaatca
     6901 ctggtgtaat attaatactt gcatggtcat taagttcagt aataaaagag ttaggtacag
     6961 ctaaattttt aatacaccta ctatcaggtt cactaccacc attcttatta ccaagtttaa
     7021 tatttggttt aggagcaata atatcttttg ctactggaac agcttatgga acaatgggta
     7081 tacttatgcc acttgcaatt ccattagcat actcattaaa tcctgatatg tcttatgtaa
     7141 tagtaagtac tagtgcagtt ttaacaggtg caatatttgg agaccattgt tctccaattt
     7201 cagatacaac aatactttct tcaatgggag ctggctgtaa tcatatagac catgttaaca
     7261 ctcaaatgcc atatgctata tttacagcag taatcactat tgtatttggg tatataccag
     7321 ctggacttgg attgccaata tatatagtat taccagtggc aatagctgct atatttgtag
     7381 gtattcaaat aattggtaag aaagttgatg aagcggaaat agaacttgta gaataaagat
     7441 ataaataagt ttcacctttt attatcacta ttttgttagt ttttagataa ttttaaaaag
     7501 ttattgaaaa taatggcgaa atatagtaaa ataaaagagt gataagcgga tgtggcggaa
     7561 ttggcagacg cactagactt aggatctagc gccattggcg tgggggttcg actcccttca
     7621 tccgcacttt acagtactta attgtactga aaaaaactgg ggttgctggc tttcggagtg
     7681 ggctatcccg tttttatttt tttgtatata taatagattg gcactttagt ataaggtgct
     7741 ttttttatag gcaaaaacag tacatttatt tctgttttat tatcattcat ctattagaat
     7801 atactttagt taagaatgtg ttaataagca gtgttcacat tcttgataaa atgtggaata
     7861 atatgtattt ttactaagac ggaaatgaaa taattaaacc attaaataat attataagat
     7921 gatgaataag tagataaatc aaattttgta ggaggatatt atggaaaaat atatatggtt
     7981 gtttccatta ctttttattt ttcatgatat ggaagagata ataggttttg gaatatggct
     8041 taaaaaaaat aaatcaatgc ttgataagaa gtatccattt atcagtaaag tttatgaaaa
     8101 ttatagtact gaaggcatgg catttgctgt gtttgaagaa tttattttat gcattatttt
     8161 ctgtatactt acagttataa cagagaatca gtatgtatat ctactatggt taggtagttt
     8221 tatagcatat accttacatt tggtaattca tatagggcag tcaatcataa taagaaaata
     8281 tataccttca cttattacca gtatcatatg cttaccaata agcatttggt gtataagtaa
     8341 gagtatttat atagttgatt gtgaaatgag tacaacaatt ctgtacagta taattggcat
     8401 tataattgta gcattgaatt taaagtttgc acagtcgctg attggaaaat ttacaaagtg
     8461 gatgtcaaac atataaattt tagtttattg gacagttcaa ggaatcagaa attggaattt
     8521 tatagtatta atattttatg gtattaatat aatgtataaa attttatagc aatgtatttc
     8581 ataagtataa agtgactaga attttaagaa atatacaaat tctataaaaa ctaaataatt
     8641 tcaagtatat tttaaaaatc ttatttttca caagtttaaa attgtaaacg atttcatcaa
     8701 gtctatgaat atacttttaa catgttatag taaatctcaa tataaattta catttggttc
     8761 tttgtgtgtt attttaataa taaattaagt gaaaatgtta ttttacatta atatataata
     8821 tctttgcata agagtgaata atataaaaga gaaataattg ataataaaaa cttaacaaaa
     8881 aaattaatac ataaaaaaaa ataaatataa tgtgttgaca tttaattgaa atattcatac
     8941 aataaaattg aaaataaata tttccaaatg agattagcga gagagtcctt tatacgaaaa
     9001 ggcgccgaag aagaaattta agaaatgcca atttttagag aagctttcag gcaaaaatat
     9061 cgctaattga tgggactctg gagagactta agttaagata ctataagtca ccgaagaagc
     9121 aaaataatat taaattatta aatctttcag gtatacaaac agggatatat aggctaggat
     9181 tattttccat gctgatatat ctttttttta tgaaaaagta caggaaataa tatcaaagtt
     9241 acttaaatac agtaggtcta attttctagg gagggttata tatgaatgaa ttgaaaagag
     9301 tatctttgta caatatacac aaagagcttg gagcaaaact tgttgaattt gctggttggg
     9361 aaatgccttt agaatatgag ggtataaata aagagcatga gaaggtcaga aaaagtgcag
     9421 gtatatttga tgtatctcat atgggagagg tacagataaa gggagcagag tcagaaaaat
     9481 ttatacaaaa cctagttaca aatgatataa gcgcattaaa gataaatgat attatatata
     9541 cacctatgtg ttatgaaaat ggtggagtag ttgatgattt attaatatat aaatttggtg
     9601 aagaagatta tttattagta ataaatgcag gtaatataga taaagatgta gcatggataa
     9661 taaaacaaag tgaaggatac aatgtagata taaaaaatat atctagtgaa gtgagtcaat
     9721 tagcaattca aggacctaaa gcagaagaaa ttcttcaaaa aatcacagat atagacttaa
     9781 actcaataaa attttataag tcaattccat caacaaaagt atgtggttgt ccttgtttag
     9841 tttcaagaac aggatatact ggggaagatg ggtttgagat atactgtaaa aataaatatg
     9901 tagaaataat ttggaatgaa gttctaaagg ttggaggaga agatatatgt ccagctggtc
     9961 taggttgtag ggatactttg agatttgaag cagctctacc tctatatgga catgaaataa
    10021 atgaacacat atctccaatt gaaggtggtt tatctatctt tgtgaaaaca aataaagaat
    10081 catttattgg caaatcaatt ttatcaaaag aaaaagaaag tggagctaaa agaaagttag
    10141 taggatttga aatgcaaggt aaaggaatgc ctagaaatgg atatgatata aggattggtg
    10201 ataaaacagt tggatttgta acaacaggat gtgcatctcc aacgacagga aaaattttag
    10261 gtatgggaat tatagattct gaatatgcaa aagtaggaaa tgaaataggt atagcaatca
    10321 gaaaaaaagt tgttcctgct gtgatagtta agaaaccttt ttataaaaaa caatataaaa
    10381 aagataatat tatattaaac aaagaaaata aattttcata tatacctgct acaagtgaag
    10441 ataaatcaaa aatgttaaaa gtagttggat taaattcagt tgatgaatta ttttcagata
    10501 taccagaaga agtaaaatta aaaagagatt taaatttgga aattggaaaa tctgaattag
    10561 aggtaagcaa aatagtaaaa agattgtcag aagaaaattt aagtttagaa gacttgactt
    10621 gttttcttgg tgctggtgca tatgaccatt atataccatc aattataaaa catataactt
    10681 caagatctga attttataca gcatataccc catatcaagc tgaaataagt cagggaactt
    10741 tacaagtagt ttttgaattt caatctatga ttgcagaaat tacaggtatg gaaattgcaa
    10801 atgcatcaat gtatgatgga gcaactgctg caatagaagc atgtataatg gcaatgaatc
    10861 agactagaaa aagtaaaata gtagtgtcaa aaactattca tcctgaaact ctgtcagtat
    10921 taagaactta cttacaatat aaagattgtg agatagtaga aattgacttt tgtaatgaat
    10981 atgggactac agatatagaa aaattaaaag cttctgtaga caaagataca gcatgtgttc
    11041 ttatacaaac tcctaatttc tttggaatta ttgaagaaat ggaagaaata gaaaagataa
    11101 ctcatgaaaa taaggctatg ttaattatga gtgtagaccc aatatcatta ggagttttaa
    11161 aaacaccagg tgagataggt gcagatattg ttgttggaga agctcaatca cttggaaacc
    11221 ctcttaattt tggaggtcct tatgtaggat ttttagctag caaatctaaa tatactagaa
    11281 aaatgccagg aagaatagtt gggcaaagtt tagatgtaga aggtaaaatt gcatatgtat
    11341 taactttaca aactagagaa cagcatgtaa gaagagaaaa agcaacttct aatatatgtt
    11401 caaatcaagc tttaaatgct cttgtagctt caatatatat ggctactatg ggtaaagaag
    11461 gatttaaaga ggttggtatg cagtctatga aaaaagcaca ttatacctac aataaacttg
    11521 tacaaactgg aaaatataag ccaatattta aaggtaagtt tttcaaagaa tttgctgtac
    11581 aaggaaatct taatatagaa actataaatg ataaactctt agaagaaaat atattaggag
    11641 gttataattt agaatacaat tatccagaat taaaaaattc aactttgctt tgtgtgactg
    11701 agaaaagaag caaagaggaa atagataagt tagttggaat aatggaggga ttataatgaa
    11761 agaatacaat agtttgttga tagatatatc taaaaaaggt aggaaagcat actcacttcc
    11821 aaagttagat atagatgata taaaaataga aaatatgatt gaccaagata tggcaagaca
    11881 aagtgagttg aatttgccag aagttggtga attagaatta gttagacatt atacattatt
    11941 atcaaataaa aactttggag ttgatacagg tttttatcct ttgggttctt gtactatgaa
    12001 atataatcct aaaataaatg aagatatggc agcacttcca aactttactg gaatgcatcc
    12061 ataccaatct tcggatacag ctcaaggttc tctttctttg atgtatgatt tatcaagaag
    12121 acttgcagaa attacaggta tggatgaagt tacactacaa ccttcagcag gttctcatgg
    12181 tgagtttaca gggcttatga ttataaaagc atatcatgaa aatagaggtg accataagag
    12241 aaccaaagtg ataattccag attctgcaca tggaacaaat ccagcaagtg cagctatggc
    12301 aaactttgat gtgattcaaa tagcatctga taaaaatgga gctgtagaca taaatgcatt
    12361 aaaagaggtt ttgaatgatg aagtagcagc tcttatgctt actaatccaa gtactcttgg
    12421 tttatttgaa aaaaatataa aagaaatagc tactcttgta catgaagcag gaggactttt
    12481 gtactatgat ggtgcaaaca tgaacgctat tatggggata acaagacctg gagatatggg
    12541 gtttgatgtg gttcatctta atcttcataa gactttttca actcctcatg gaggtggagg
    12601 tccaggagct ggtcctgttg gagttaaaaa agaattagta ccttttttac caataccagt
    12661 aattgaaaga aaagaagata agtatgtact aaattatgat agagaaaaat ctattgggaa
    12721 aattaaaaat ttctatggta attttggagt tcttgtaaga gcttacacat atatactaac
    12781 tatgggaagg gatggactta aagaggctag tgaaatggca gttttaaatg ctaattatat
    12841 aaaggaaagt ataaaagatg attatatttt gccaatagat accttgtgta agcatgagtt
    12901 tgtattaggt ggattgccaa gaggagaggc caatataaaa actatcgata ttgcaaaaag
    12961 actactagat tatggatacc atcctccaac aatgtacttt cctcttatta taaatgaggc
    13021 acttatgata gaacctacag aaagtgagag tatagagaca ttagatagtt ttatagaagc
    13081 tatgaaaagt gttgctaaag aggcaaagga agaaccagaa ctattgaaaa ctgctccaca
    13141 taatactttg gtcaaaagag tagatgatgc aagggcagta aagaaaccta tactaacatg
    13201 gtcacaaaga taaatagtta aaaagtagag atttaaagta taaagagaat taaatttgta
    13261 agaaaaagct atctaactta atctagttta gatagctttt ttgtatatta gtatgtatgg
    13321 tattttctat ataaagtttt aaattatatt agtgcttata tagaatattg atatgatgat
    13381 tatgtataga tattaataag aattgttgaa tttatcttgc cttaacttta tttactcttt
    13441 tatattaaga aaaacttaac taaaatatag cgaaattcat aaaaatttag gaaatcttaa
    13501 gaattataat atttaaatct ttagatttat attttattat ataaactata gaataataaa
    13561 ataaaaaaat tgagaatttt ataatatatt tgtagatttg agtataaaaa agtgctaagt
    13621 tgaaaggagt aaaatatgga taaggttaat ttagaaaggt atagttgtga tataaatgtt
    13681 ggtttaaata aaaatcaact tcaaagtaga atagatgata atttaattaa tgcatttgat
    13741 aatggaaaaa ccaaaacata taaacaaatt tttaaagaca atatatttac actttttaat
    13801 ctcataaata ttgttttagt ctgtttatta gtttcagttg gttcttttaa aaatacctta
    13861 tttatattta ttgctgtaat taatactatt ataggagtaa tacaagagat aagagctaaa
    13921 agattattgg acaatctatc tgttatagtt tcaaataagg tatctgtcat aagagaaaaa
    13981 gagaaaaaag agattgatgt acaagaatta gtattagatg atattatgat tttaaaaaca
    14041 ggtaatcaaa tttgtgcaga ttcaaaagtt ttaaatggaa aattagaggt aaatgagtct
    14101 ttggttacag gtgaatctga tattattata aaaaataaag gcgatttttt atattctgga
    14161 agttttgtag tttctggaga agcttttgta agagttgaaa atataggaaa agataactat
    14221 gcaaataaga tagctaatga tgcaaagatt tctaaaaaac ataattctca acttagaaat
    14281 tcattaaatg caatattaaa aattgtaggt ataataataa ttcctttagg aattatattg
    14341 tttgcaaaac aacattttgg aaatggagat tctatagcta catctgtagt aggtacagtg
    14401 gcagctgtaa atggtatgat accagaggga ttaacattac ttacgagcat tgctctagct
    14461 gtaggaacta taaaacttgc tagtcataaa actttagtgc aagaactgta ctgtgtagag
    14521 actcttgcta gagttgatac actatgtctt gataagacag gtacaattac agaaggtaaa
    14581 atgcaagttg atgatatagt aatgttggaa gaagtggata ttaatgaaat aatggggaat
    14641 atatgtaatt ctctcaaaga tgataatgca acactaaatg caataagaga taagtataat
    14701 gttttagata cgtataaagc taagaattta ataccatttt cttcagaaag aaaatacagt
    14761 ggggttacct ttgaaaataa aggtacatat ttattaggtg catttgaatt tatatttaag
    14821 gaaaaaaata aaaaacttag gatagaagtt gaaagatatt ctaaaaaagg aaacagagta
    14881 atagttttag ctcatagtga ttcttatatg gaagataata atattcctga agatataaag
    14941 ccactagctt ttatattgat attggataaa attagagatg aagctaagga aactttagaa
    15001 tttttttaca atgaaggtgt agatataaaa attatatctg gtgacaatcc tataacagta
    15061 agtgaggtag ctagaaaagc aggtcttaaa acagctagta attttattga tgcaacaaca
    15121 cttaaaaatg atagtgatat atacaaagca gttgataaat acagtgtttt tggaagggta
    15181 agcccacaac agaaaaaaca aatgatttta gcattaaaaa aacaaaatca tacagtagct
    15241 atgactggag atggtgtaaa tgatgtgcta gcacttaaag aagcggattg tagcattgcc
    15301 atggcatctg gaagtgatgt tactaagaat gtgtctaatt tagtcttatt agattcaaac
    15361 tttgcatcaa tgccaaaggt tgttatggag ggaagaaaag taattaataa cattcaaaga
    15421 gcatcttctt tgtttttagt aaagacaatt ttttcattct tcttgtcgtt attaacatta
    15481 ttcttcttca gtagacagta tccatttgtt cctatacaat tatcactcat tggggctgta
    15541 acagtgggta taccatcatt cttcttagct cttgaagcaa acaaaagtag aatttcagga
    15601 aattttttac tcaatatatt aaaaaatgct ttaccaggag cactatgtgt gacagtaaat
    15661 gtaattattg tttacaatat agttgaatat ttaggttata gttcaagtgt attttccaca
    15721 atgtgtgcta tattaactgg tgtatgtggt cttttaatat taagacaaca atgtttgcca
    15781 tttaataaag aaagattatt tttaatagta agtatgacta ttgcatttgt tattgggatt
    15841 ctatttttag gtggattatt ctcatttgta gcattgagta gagaattaat tctcataact
    15901 atggcattag caatattaat gccaattatg ataaaagtta tgttatttgt cttagatgag
    15961 atattagaga caattgttcc agatttaaat taattttaaa atgatataaa taagagcagt
    16021 tttagttgaa ctgctctttt tagatgtgtt taattttatg taagaatatg tatttttatt
    16081 aatcagctat atatgagcaa cagtagtcaa caacttcatt aacctttaag tcaaaacttg
    16141 aatcactagg aacattaaat ttttgccctt ctttataagt tacaaactca ttgcttccag
    16201 gcagttttac atccatactt ccagcaagca tctccattat ttcttcttct ctagtagaaa
    16261 aagtgtattc tcctggcaac attaatccta aagtttttct ttctccatta ggcagtatta
    16321 ttactctgct acttacctta ccatcaaaat aaacgtttgc cttctttact gcagtaacat
    16381 tcttaaattc actcattaga taaaacctcc aaaattattt gtacatatat attatataaa
    16441 aataatgtaa aaaatgctat atatttacaa aaaaatttag tatttattaa aaaaattaat
    16501 aagaataaaa aagagatgaa attgcttaaa ttgataaaaa atataaaata aattgcaaag
    16561 taagcaagaa aagaataagt tgaagagtta tatattataa atattaaaaa ttttagtatt
    16621 aataaaaaag atattacatt aatatgaaaa tatagg
//
LOCUS       DAEHWO010000096        15978 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEHWO010000096 DAEHWO010000000
VERSION     DAEHWO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15978
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.096"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="KNP54_003396"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="KNP54_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBF0894256.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="KNP54_003397"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="KNP54_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBF0894257.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="KNP54_003398"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="KNP54_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBF0894258.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1245..1670
                     /gene="rplK"
                     /locus_tag="KNP54_003399"
     CDS             1245..1670
                     /gene="rplK"
                     /locus_tag="KNP54_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBF0894259.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1741..2439
                     /gene="rplA"
                     /locus_tag="KNP54_003400"
     CDS             1741..2439
                     /gene="rplA"
                     /locus_tag="KNP54_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBF0894260.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2491..2619
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2662..3168
                     /locus_tag="KNP54_003401"
     CDS             2662..3168
                     /locus_tag="KNP54_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBF0894261.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3226..3591
                     /gene="rplL"
                     /locus_tag="KNP54_003402"
     CDS             3226..3591
                     /gene="rplL"
                     /locus_tag="KNP54_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBF0894262.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3982..4770
                     /locus_tag="KNP54_003403"
     CDS             3982..4770
                     /locus_tag="KNP54_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBF0894263.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5241..8957
                     /gene="rpoB"
                     /locus_tag="KNP54_003404"
     CDS             5241..8957
                     /gene="rpoB"
                     /locus_tag="KNP54_003404"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBF0894264.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            8999..12484
                     /gene="rpoC"
                     /locus_tag="KNP54_003405"
     CDS             8999..12484
                     /gene="rpoC"
                     /locus_tag="KNP54_003405"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBF0894265.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12773..13195
                     /gene="rpsL"
                     /locus_tag="KNP54_003406"
     CDS             12773..13195
                     /gene="rpsL"
                     /locus_tag="KNP54_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBF0894266.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13319..13789
                     /gene="rpsG"
                     /locus_tag="KNP54_003407"
     CDS             13319..13789
                     /gene="rpsG"
                     /locus_tag="KNP54_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBF0894267.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13838..15904
                     /gene="fusA"
                     /locus_tag="KNP54_003408"
     CDS             13838..15904
                     /gene="fusA"
                     /locus_tag="KNP54_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBF0894268.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6257 a         1989 c         3249 g         4483 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttatgct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa ataatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttgtttggat
      481 acttaaaaga aactaaacaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaagta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gttttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtgccat taagtgaaga cgaagtcaaa gctatgggga tagacacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagatacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atattataga aaaatctgag gaggtgcgct caaaatggct aaaaaagtta
     1261 taggtcaaat aaaattacaa atacctgcag gaaaggctac tccagcgcca ccagttggac
     1321 cagcattagg acaacatggt gttaatataa tgggattcac aaaagaattt aatgctaaaa
     1381 ctgcagatca agctggaatg ataataccag ttgttataac tgtatatcaa gatagatcat
     1441 tcagttttat aacaaaaact ccaccagctg cagttttaat taaaaaagca ttaaacttaa
     1501 aatcaggttc tggagaacca aacaagaaaa aagttgctaa aatgacttca gctcaagtaa
     1561 gagaaatagc tgaattaaag atgcctgact taaatgctgc atcagtagaa gctgctatga
     1621 gtatgatagc tggtactgct agaagcatgg gtgttgtaat cgaagactaa ttaaaagata
     1681 cacttttttt tataaagtgg gaggctagaa gccgaaatta accacgagga ggaaaataaa
     1741 atggctaaaa aaggtaaaag atatgcaggt gcattacaaa aagtagatag aactaaattt
     1801 tatgatgcat cagaagcatt aacattagtt tcagatatag ctggagctaa atttgatgag
     1861 acagtagaag cacacattaa attaggtgtt gactcaagac atgctgacca acaagtaaga
     1921 ggtgcagttg tattacctca tggaactggt aaaacaaaaa gagttttagt ttttgctaaa
     1981 ggtgaaaaag ctaaagaagc tgaacaagct ggtgctgact ttgtaggagc tgaagaatta
     2041 gttcaaaaaa tacaaggtga aaactggttt gactttgata tagtagttgc tactccagat
     2101 atgatgggtg tagtaggtag attaggtaga gtattaggac ctaaaggttt aatgccaaac
     2161 cctaaatcag gaacagttac atttgatgta gctaaagcta tagatgaaat aaaagctggt
     2221 aaagttgaat acagattaga caaaactaac ataatacacg ttccagtagg aaaagtatca
     2281 tttggtggag aaaaattaac tgaaaacttt actgcattaa tggatgctat aataaaagct
     2341 aaaccagctg ctgctaaagg acaatattta agaagtataa cagtagcttc ttcaatggga
     2401 cctggagtta aaataaaccc agcaagaaca gctgaataat aaaactgttg acacaggttg
     2461 acaaaaatgt tattatatca cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg
     2521 ggtgcgaaag cttaatatcc cgccgaggtt ttagataaat tgagattact aaagcttttg
     2581 atgtctactt ttggcaacaa aagcttttta taatgttgcg gtaaatacta agcctatttg
     2641 gtgaaggagg tgcacatcta tatgagaaaa gctatagaaa ttaaatcaga agttgtttct
     2701 gagatagttg aaaagttaca aaaatcttct gctgctgttg ttgtagatta caaaggatta
     2761 acagttgaag aagtaactga gttaagaaaa caaatgagag aagctggtgt agattacaaa
     2821 gtatacaaaa atactttagt tagaagagca gctaaagaag ttggtataga gcaatttaat
     2881 gatgaattat tagttggaac taatgccata gcatttggat atgatgatcc agttgctcca
     2941 gctagaatat taaaaggatt catggattct catccaaaaa tgaaattaaa gatgggtatt
     3001 gtggaaggtg cattctatga tgaatctaag attgttgaaa tggctaacat accatcaaga
     3061 gaagttctta tcgctaaatt acttggtagc ttaaaagctc cagtatcaaa cttcgcatac
     3121 ttaatagatg caatagcgaa aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa
     3181 aaaattataa atattaattt gaaataaaat tcggaggtgc taaaaatgac aatagaacaa
     3241 atattagaag ctatagaaaa tatgaaagtt ttagaattaa atgaattagt taaagctgct
     3301 gaagaaaaat tcggtgtatc agcttcagct ccagtaatgg tagctggtgc agctgctggt
     3361 ggaccagctg ctgaagaaaa aactgagttt gatgtagtat taactgacgt tggttcttca
     3421 aaagttggag ttataaaagc agttagagaa ataacaggat taggattaaa agaagctaaa
     3481 gaagtagttg acaatgctcc taagacagtt aaagaaggag cttctaaaga agaagctgat
     3541 caaataaaag agaaattaga agctgctgga gctaaagtag aagttaagta gtttctttaa
     3601 aaagataccc attgggtatc tttttttatt tataaaaaac tataaagaaa gtatttggaa
     3661 ttataaagaa agtattttta taaaataaaa aaaatttata taatagtact aaattaaggg
     3721 tatcatatat ggtgtaatgg tattttaatt taacattatt atcaaattaa aatataaaca
     3781 attgttgtaa tgtctgtata taaagtatat aattaaacta aaatgtaaaa ttttacattt
     3841 tagtttaaaa aaatacacga gtgtttataa ataaaatgta ataaataatt aattaacaaa
     3901 tataaatttt aaaataagtt agatatttag aaaaatcgaa atttgtagga tttaaaggac
     3961 atattcaagg aggagttaat aatggaaaaa ttacaaggaa aaattgcagt agttactgca
     4021 gcaacaaaag gtattggatt agcatcagca gagatattag caaaaaatgg agcaactgtg
     4081 tacttagcag ctcgttcaga agaattagct aatgaagtta taaataaaat aagtgcagaa
     4141 ggtggttgtg ctaagtttgt ttactttaat gctcgtgaag aagagacctt tacctcaatg
     4201 atagaagagg tagttaaaaa agaaggtaag atagatatac ttgtaaacaa ttttggttca
     4261 acaaaccctt ctcttgacaa agaccttgta actggggata cagataattt ctttgacaca
     4321 gtaaatacta atttaaaaag tgtgtattta ccatgtaaag cagcaattcc tcatatgata
     4381 aagaatggaa aaggaagtat agtaaatata tcaagtatag gttcagtatt acctgattta
     4441 tctagaatag cttactgtgt atcaaaagca gcaatcaact cattaactca aaacatagct
     4501 acacaatatg ctaaagacaa tgttagatgt aatgctgtac ttccagggct tattgcaact
     4561 aaagcagcat tagacaatat gtctccagag ttcataaaag aatttttaaa gcatgttcct
     4621 ttaaatcgta taggggaacc agatgatata gcaaaagctg ttctattcta tgctagtgat
     4681 gactcatcat ttataacagg ggatttactt gaagttgcag gaggatttgg tttacctact
     4741 ccacaatttg cagataatat attaggataa ttaaattact aatatgcaat gaaagcttat
     4801 gcattagtta tagtagaaat gatattttta taaaggccat agatataatt tatattggaa
     4861 aggtttgagg ttcaaaattc caagttaaat ttatttatgg tctttatttt gtatatttta
     4921 ataaattgta tatatttgta taaatgtaat tatttacaat cattttaata tggaattata
     4981 attaaatagg ggggatggta cttgtataaa attttttata gaaaattaga cctataaatg
     5041 aaaaatatgg attttatatt ggaaaattgt acataataca taatatatgc ttaaaataat
     5101 ttacaaaaaa tcaaaaataa tgcatagttt acatataaga taaaaaatat attgaaaaat
     5161 acttgacatt atgctaaaat tattagatgc gttagaatga actattgttt tatttttaat
     5221 tattgagagg tgaaaagtga atgccacatc ctgtcacgat aggtaaaaga actagaatga
     5281 gcttttctaa aattaaggaa atagctgatg tgccaaatct tatagaaatt caagtagatt
     5341 cctatgagtg gtttttaaaa gaaggtttaa aagaagtgtt tgatgatatt tcaccaatag
     5401 aagattatac tggtaatctt atattggaat ttgtcgacta ttctctagat gataaaccaa
     5461 agtacgatat agaagagtgt aaagagagag atgctacata ttgtgcacct ctaaaggtta
     5521 aggtaagact tataaataaa gaaacaggtg agataaaaga acaagaagtg tttatgggtg
     5581 acttcccttt aatgacagaa agaggaactt tcgttataaa tggagcagaa agagttatag
     5641 taagtcaatt agttagatct cctggtgttt actatgcgga agaaagagat aaaacaggta
     5701 agagattgat ttcatctact gtaattccta atagaggagc atggttagaa tatgaaacag
     5761 attctaatga tgtaatatct gtaagagttg atagaacaag aaaacaacca gttacagttt
     5821 tacttagagc tttaggaata ggaacagatg cagagataat tgacctttta ggagaagatg
     5881 agagattatc tgctacatta gaaaaagata atactaagac agtagaagaa ggtcttgtag
     5941 agatatacaa aaaattaaga ccaggtgaac ctcctactgt agaaagtgca tcatctttat
     6001 taaatgcttt attctttgac ccaaaaagat atgacctagc aaaagttggt agatataaat
     6061 tcaataagaa acttgcttta tgttatagaa taatgaataa aatttcagca gaagacataa
     6121 taaatccaga aactggagaa gtatttgtaa aagctggaga aaaaataagc tatgatttgg
     6181 ctaaagccat acaaaatgca ggtataaatg tagtaaatct actaatggat gatgataaaa
     6241 aagttagagt tataggaaat aattttgtgg atattaagtc tcacattgat tttgacatag
     6301 atgatttaaa cataaaagaa aaagtacatt atccaacttt aaaagaaatt ttagatggat
     6361 atagtgatga agaagaaata aaagaggcta taaaatcaag aattaaagaa cttataccaa
     6421 aacatatatt attagatgat ataatagctt caataagtta tgagttcaat atattctata
     6481 atataggaaa tattgatgat atagatcacc taggaaacag aagaataaga tctgtaggtg
     6541 aattgttaca aaatcaagtt agaattggtc tttcaagaat ggaaagagtt ataaaagaaa
     6601 gaatgacggt tcaagatatg gaagctataa cgcctcaagc gttagttaac ataagaccag
     6661 tttcagctgc aataaaagaa ttttttggta gttctcagtt atctcagttc atggatcaaa
     6721 caaatcctct atctgagtta acgcataaga gaagattatc agcccttggg cctggaggtc
     6781 tttcaagaga aagagctgga ttcgaagtgc gtgacgttca ccattcacac tatggtagaa
     6841 tgtgtccaat agagactcca gagggaccaa atatcggtct tataaactct ctaggaactt
     6901 atgcaaaaat aaatgaattt ggatttatag aatcaccata tagaaaattt gataaagaaa
     6961 catcaacagt tactgatgaa atacattatt taactgctga cgaagaagat ttattcgtaa
     7021 gagctcaggc aaatgagcca ttaacagaag atggtaaatt cgtaaaccat agagttgttt
     7081 gtagaactgt aaatggtgct gttgaaatgg ttcctgaaag tagagtagat tacatggata
     7141 tatctcctaa gcaggttgta tctgttgcca ctgctatgat acctttctta gaaaatgatg
     7201 atgccaaccg tgcccttatg ggagcgaaca tgcagcgtca ggcagtgcct ctagttagaa
     7261 gagaagcacc aattatagga actggtatag aatacagagc agcaaaagac tctggagcag
     7321 ttgttgttgc tagaaattct ggtatagcag aaagagtaac agcagatgaa ataattataa
     7381 aaagagaaga tggaaacaga gatagatata atctacttaa gtttaaacgt tcaaactcag
     7441 gtacttgtat aaatcaaaca cctataataa ataagggtga ccagataata aaaggtgatg
     7501 ttatagcaga tggtccagca actgatttag gagaagttgc acttggaaga aactgtctta
     7561 tagcattcat gacttgggaa ggttataact acgaggatgc tatattaata aatgaaagat
     7621 tagttaaaga agatagatta tcaacaattc atatagaaga atatgaatgt gaagctagag
     7681 atacaaaact agggccagag gaaataacta gagatatacc taatgttgga gatagtgcaa
     7741 ttaagaactt agatgacaga ggtataataa gaataggtgc agaagtagac tcaggtgata
     7801 tattagttgg taaagtaact ccaaaaggag aaactgaact tactgctgag gaaagattac
     7861 ttcgtgcaat atttggagaa aaggctagag aagttagaga tacttcactt aaagtgcctc
     7921 atggtgaatc tggtataata gttgatgtaa aagtatttac tagagaaaat ggagatgatt
     7981 tatctccagg agtaaatgaa ttagtaagat gctatatagc taaaaagaga aaaataaaag
     8041 ttggagataa aatggctggt cgtcatggta ataaaggggt tatctcaaga gtattacctg
     8101 aagaagatat gccattcatg gaaaatggaa caccactaga cataatactt aacccacaag
     8161 gtataccatc acgtatgaac attggtcagg ttttagaagt tcatttagga cttgctgcta
     8221 agacattagg atggtatgta gcaacatcag tattcgatgg tgctaatgag tatgacataa
     8281 tggatgctct tgaagaagct gggtatccta gagatggtaa attaacttta tatgatggta
     8341 gaacaggtga gtcttttgac aacagaataa ctgttggata tatgtactac ttgaaactac
     8401 atcacttagt agatgaaaaa ctacatgcaa gaagtactgg accatactca ttagttactc
     8461 aacagccact aggtggtaaa gcacaatttg gtggacaaag atttggagag atggaggttt
     8521 gggctctgga agcatatgga gctgctcaca tacttcaaga aatacttact gttaagtctg
     8581 atgacgttgt aggtcgtgtt agaacatatg aagctatagt taaaggtgaa aatatacctg
     8641 aaccaggaat cccagaatca tttaaggttc ttataaaaga acttcaaagt ttatgcttag
     8701 atgtaaaagt attgacagat gaagaccaag aaatagaagt aagagaatct gtggatgaag
     8761 atgatacaat aggtgaattt gagctagatg ttgtaaatca tatgggagaa gttgaagaaa
     8821 gtaatataat agaagaaatt gaagatgatt ttgcagaaaa tgcagaagat gaggatatag
     8881 agaatttaga agaattcact gaagatgatt tatttgaaga agaaatagat tttgatagtg
     8941 atgactttga tatgtaaatt taattaatgt aaatctcaaa tagaagggag agaactcctt
     9001 gtttgaatta aacaatttcg agtcgataaa aatagcattg gcttctccag aaaaaataag
     9061 acaatggtct aggggagaag ttaaaaagcc agaaactata aattaccgta ctttaaaacc
     9121 agaaaaagat ggtcttttct gtgaaagaat atttggacca caaaaagact gggagtgcca
     9181 ctgtggtaaa tatagaagag ttagatataa aggtgtagtt tgtgatagat gtggagtaga
     9241 agtaactaaa tcaaaagtaa gaagagagag aatgggacat atagagctag ctgctcctat
     9301 gtctcacatc tggtacttca aaggtatacc aagtagaatg ggacttttac ttgatatgtc
     9361 accaagatcg ttagaaaaaa tattatactt tgcctcatat gtggtagttg atccaggaga
     9421 gactggatta aacgaaaaac aattgcttac agaaaaagaa tacagaactg ctcttgaaaa
     9481 gtatggatat acttttactg taggaatggg tgctgaagct gtaaaaacat tactacaaaa
     9541 tatagattta gagcaacaaa gtaaagacct aagagcggag ttaaaagata gtacagggca
     9601 aaagaaagtt agaacaataa gaagattaga agttgtagag gcatttaaaa agtctggaaa
     9661 taaaccagaa tggatgattt tagatgcaat accagtaata ccaccagatt taagaccaat
     9721 ggtacaactt gatggtggaa gatttgcgac ttcagaccta aatgatttat atagaagagt
     9781 tataaataga aacaacagac ttaaaagatt attagagctt ggagctccag atataattgt
     9841 aagaaatgaa aaaagaatgc ttcaagaagc tgttgatgca ttgatagata atggtagaag
     9901 aggtagacct gtaacaggac ctggaaatag accacttaaa tctttatcag atatgttaaa
     9961 aggtaagcaa ggtcgtttcc gtcaaaactt acttggtaag cgtgttgact actcaggacg
    10021 ttctgttata gttgttggac cagaacttaa attttatcaa tgtggacttc caaagaagat
    10081 ggcattagaa ttattcaagc catttgttat ggataaatta gttaaagaag gttatgcaca
    10141 taatataaaa agtgcgaaat ctatagtaga aaaagttaag ccagaagttt gggatgtttt
    10201 agaagatgtt ataaaaagtc atccagttct tcttaaccgt gcaccgactc tacatagatt
    10261 aggtatacaa gcatttgaac caatcttagt tgaaggtaag gctataaaac tacatcctct
    10321 tgtatgtaca gcttataatg cagactttga tggtgaccaa atggcagttc atgtaccttt
    10381 atcagtagaa gcacaagcag aagcaagatt cttaatgctt tctgtaaata atatacttgc
    10441 tcctaaagat ggttcaccta taactactcc atctcaggat atggttttag gttgctatta
    10501 tctaacaata gaagcccaag atggagctaa aggaacaggt atggtattta aagactttaa
    10561 tgaactatta cttgcttatt acaataaatc agttcatcta catgcattag tgaaacttaa
    10621 ggtaacactt gaagatggaa gaagttcatt ggttgaaagt actgttggta gatttatatt
    10681 taatgaaaat atacctcaag acttaggttt tgtagataga aaagaaaatc catttgcact
    10741 tgaagttgat ttcttagcag ataaaaaatc tcttggtaaa ataatagata aatgctttag
    10801 aaaacacgga aatacagaaa cagctgaatt actagattat ataaaagctc taggatttaa
    10861 atattctaca ttaggtggca taacagttgc tgttgatgat atgagtgtcc cagaagaaaa
    10921 gaaagtattt atagctgagg cagaagctaa agttgataag tatgaaaaag catacagaag
    10981 aggtctaatc tctgatgaag aaagatatga aaaagttata gagacatgga cagaaacaac
    11041 tgataaagtt actgatgctc ttatgggtgg actagataga ttaaataata tatatataat
    11101 ggcacattca ggagccagag gttctaaaaa ccaaattaga cagctggcag gtatgcgtgg
    11161 tcttatggca aatgcatctg gtaaaacagt tgagatacca gttaaatcta atttccgtga
    11221 aggtttatca gtactagaat actttacatc ttcacatggt gccagaaaag gtcttgccga
    11281 tacagctata cgtacagctg aatctggata tttaacaaga agacttgttg atgtaagtca
    11341 agatgttatt gtaagggaaa tagattgtgg aacagaagat actacagaga tttatgctat
    11401 aaaagaagga aatgaagtta tagaagagat atatgataga attgtaggaa gatatactat
    11461 agaccctata ttaaatcctg aaactggaga agttatagtt gaggctgatt caatgataca
    11521 agaagatgaa gcagaaacta tagtagcttt aggaattgaa aaaattagga taagaacagt
    11581 tcttaactgt aaaactaatc atggagtttg ttctaagtgt tatggtagaa acttggcaac
    11641 aggaaaagaa gttaatatag gtgaagcagt tggtataata gcagctcaat ctatcggtga
    11701 gccgggtact cagcttacaa tgcgtacatt ccatactgga ggagttgcag gagctgatat
    11761 aactcaaggt ctaccaaggg ttgaagaatt atttgaagct agaaaaccaa aaggattagc
    11821 tgtaataact gaagtatctg gtagagttga aattgatgaa acaggaaaga gaaaagaagt
    11881 aaatgtaata ccagaagaag gcgagactca aacatatgta attccatatg gttctagatt
    11941 aaaagttaag caaggtcaaa tgctagaggc tggagaccct ctaacacaag gatttataaa
    12001 tcctcatgat atagtaagag taaatggtgt taagggagtt caagaatata tagttaaaga
    12061 agttcaaaga gtgtatagac ttcaaggggt tgatgttaat gataagcata tagaagttat
    12121 agtaagacaa atgctatcta aagtaaaagt tgaagaccca ggagatacag atttattgcc
    12181 aggtggatat gaagatgtat taacattcaa tgaatgtaat aaagatgcta tagataaagg
    12241 tctaagacca gcagttgcta aaagagtttt acttggtata actaaagcat ctcttgcaac
    12301 tgattcattc ttatcagcag cttctttcca agaaacaaca agagtattaa cagaggcagc
    12361 aataaaaggt aaagaagacc acttaatagg acttaaagaa aatgttatat taggtaagtt
    12421 aataccagca ggaacaggaa tgaagaaata tagaaatata gctgttgaaa aaattgaaga
    12481 ttaatagcat atagagtaaa gaaatcttga caaccattat ttgtggtgtt aaaatagtaa
    12541 agtgtgttgt ttaaaagtac actaagggct tgaacaagtt cttagtgact tttagatggc
    12601 aataaatgag aactaaaaag catcaagcta gaaaagtgct aatatcacat atttatgtgt
    12661 tatagacatt aaattgtaag taacgaatgt tacaatcagt cagtatgaat attcatattg
    12721 atgtagttgg cggtcactga taagatcgaa aatttggaag gaggtgcaga tgatgccaac
    12781 aattaaccaa ttagttcgta aaagtagaaa agcgctagag aagaaatcta ctgctccagc
    12841 attacaaaaa ggttacaact ctttaaataa gaaagtaact gacgctagtg ccccacaaaa
    12901 aagaggggtt tgtacttcag taaaaacagt tactcctaag aagcctaact cagctttaag
    12961 aaaagttgcc agagttagat taactaatgg tatagaagtt tctgcttata taccaggaga
    13021 aggacacaac ttacaagagc atagtgttgt tcttataaga ggaggaagag taaaagacct
    13081 tccaggggtt agataccata tactaagagg tactctagat acagcaggtg ttgataagag
    13141 aagacaatca agatctaaat acggtgcgaa gagacctaaa gaagctaaaa agtaaaaaca
    13201 attaatgatt gattatagtt cggtgcttta aatatatata tatttacggc atcacggcat
    13261 taaatgattt atgtcgagta cctatgattt aagttaaata attaaggagg gaagcgaaat
    13321 gccaagaaaa ggtaatattc caaaaagaga agttttacca gatcctatgt atgggagtaa
    13381 ggtagttact aaattaataa ataatctaat ggtagacgga aaaaaaggaa agtctcaaag
    13441 aatagtttat gatgctttcg caattgttgc tgaaaagaca ggagaagaag ctttagaagt
    13501 atttaataaa gcaatggata atataatgcc tgttttagaa gtaaaagcaa gaagagttgg
    13561 tggggcaaac taccaagtgc caatcgaagt tagacctgaa agaagacaaa cattaggttt
    13621 aagatggcta gtaaaatata ctagagctcg tggagaaaaa ggaatggttg aaaagctagc
    13681 taaagagata atggacgcag ctaacaacac tggagcttca gttaagaaaa aagaagatac
    13741 tcataaaatg gcagaagcta ataaagcatt tgctcattac agatggtagg atatatagat
    13801 atcttataaa attgaggata tcataaggag gataaccatg gctagaaagt ttcctttgga
    13861 aagaactagg aatataggaa tcatggctca tatagatgca ggaaaaacta ctactacaga
    13921 aagaatcctg ttttatactg ggcaaactca taaaatagga gaaactcatg aaggagcttc
    13981 tcaaatggac tggatggagc aagaaaagga aagaggtata acaataactt ctgccgctac
    14041 tactgcttca tggaaagacc atagaataaa cataatagat actcctggac acgtggactt
    14101 cacagttgag gttgaaagat ctctaagagt tcttgacggt tcagttgctg tattctgtgc
    14161 aaaaggtggg gttgagcctc aatcagaaaa tgtatggaga caagctgaaa cttatggagt
    14221 acctagaata gcttttgtaa ataaaatgga tatattaggt gcagatttct acaatgttgt
    14281 aagcatgatg aaatctagat taaattctaa tgcagttcct atgcaattac caataggtaa
    14341 agaagattca tttataggta taatagactt attaaaaatg gatgctgtta tatacaaaga
    14401 cgacctaggg gttgaaatgg aagaaacaga tataccagaa gatatgaaag aattagctgc
    14461 tgagtggaga gaaaaattag ttgaatcagt agctgaaact gatgaagaat taatgatgaa
    14521 ataccttgaa ggtgaagaac ttactataga tgaattaaaa gttgctataa gaaaagctac
    14581 tatagcttgt gaaatgaacc cagttttctg tggtacagct tatagaaaca aaggtgttca
    14641 gttagtaata gatgcagttt tagattactt accagcgcca actgatatac cagctataaa
    14701 aggtatatta gcagatggag aagaagctga aagacattct tctgatgaag agccattctc
    14761 tgcattagca ttcaaaataa tgactgaccc attcgttgga aaactagcgt tcttcagagt
    14821 ttattctgga acattagaat caggttctta tgttttaaat gcaactaaga ataagagaga
    14881 aagaattggt cgtatattac aaatgcatgc taatacaaga gaagaaataa ctaaagtgta
    14941 tgctggagat atagcagcag cagtaggatt aaaagatact actactggag acacattatg
    15001 tgaccctgct aatccaataa tacttgaatc tatggaattc cctgagccag ttatatctgt
    15061 tgctatagaa ccaagttcta aagcagctca agaaaaaatg ggtatagctc ttcaaaaatt
    15121 agctgaagaa gacccaactt tcacagttaa gactgaccaa gaaacaggac aaactataat
    15181 atctggtatg ggtgaattac acttagagat aatagtagat agattattaa gagaatttaa
    15241 agtagaagct aaagttggtg caccacaagt tgcatataga gagactataa ctcaaccagt
    15301 tgatgttgaa tacaagtact ctaagcaatc aggtggtaga ggacaatacg gtcacgttaa
    15361 gattagagtt gctcctcaag agccaggtga aggatacaaa ttcacaaaca aaactgttgg
    15421 tggatcagta ccaaaagaat atgttggtcc agttgacatg ggtatacaag gagctatgca
    15481 atctggtata gttgctggat atccagttgt agacgttgct gttgagttat atgatggttc
    15541 ttaccatgag gttgactctt ctgagatggc gtttaagatg gctggttcaa tggcattcaa
    15601 agatgctatg aagaaaggta atgcagttct tttagagcct tacttcaaag tagaagttgt
    15661 tactccagaa gattacatgg gagatgttat gggtgactta aactcaagaa gaggattaat
    15721 ccaaggtatg gaagctagaa gtggtgcaca agttataaat gcattcgttc cactttcaga
    15781 aatgtttgga tactcaacag acctaagatc ttcaactcaa ggtcgtgcaa cttacacaat
    15841 gatattcgat cactatgagc aagttccagc ttcagttgct aagaaaatag ctgaaggaaa
    15901 ataatttaaa aataattaat aatataaata taaaaaataa tcagctagat gagagatatc
    15961 tctcatctag cacaagat
//
LOCUS       DAEHWO010000097        15898 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEHWO010000097 DAEHWO010000000
VERSION     DAEHWO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.097"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            421..1344
                     /locus_tag="KNP54_003409"
     CDS             421..1344
                     /locus_tag="KNP54_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBF0894269.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTDIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1319..2146
                     /gene="panB"
                     /locus_tag="KNP54_003410"
     CDS             1319..2146
                     /gene="panB"
                     /locus_tag="KNP54_003410"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBF0894270.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIIKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            2165..3013
                     /locus_tag="KNP54_003411"
     CDS             2165..3013
                     /locus_tag="KNP54_003411"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBF0894271.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSIFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3424..3606
                     /locus_tag="KNP54_003412"
     CDS             3424..3606
                     /locus_tag="KNP54_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894272.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            4433..5347
                     /locus_tag="KNP54_003413"
     CDS             4433..5347
                     /locus_tag="KNP54_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBF0894273.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            5737..6384
                     /locus_tag="KNP54_003414"
     CDS             5737..6384
                     /locus_tag="KNP54_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBF0894274.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(6551..7120)
                     /locus_tag="KNP54_003415"
     CDS             complement(6551..7120)
                     /locus_tag="KNP54_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894275.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(7125..8024)
                     /locus_tag="KNP54_003416"
     CDS             complement(7125..8024)
                     /locus_tag="KNP54_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0894276.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIIFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(8035..8184)
                     /locus_tag="KNP54_003417"
     CDS             complement(8035..8184)
                     /locus_tag="KNP54_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894277.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(8177..8761)
                     /locus_tag="KNP54_003418"
     CDS             complement(8177..8761)
                     /locus_tag="KNP54_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBF0894278.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            9150..10475
                     /gene="cdeA"
                     /locus_tag="KNP54_003419"
     CDS             9150..10475
                     /gene="cdeA"
                     /locus_tag="KNP54_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBF0894279.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIFALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(10570..11364)
                     /locus_tag="KNP54_003420"
     CDS             complement(10570..11364)
                     /locus_tag="KNP54_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894280.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMIIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(11365..12240)
                     /locus_tag="KNP54_003421"
     CDS             complement(11365..12240)
                     /locus_tag="KNP54_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894281.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLSFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSESDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(12244..12612)
                     /locus_tag="KNP54_003422"
     CDS             complement(12244..12612)
                     /locus_tag="KNP54_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0894282.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(12795..13454)
                     /gene="deoC"
                     /locus_tag="KNP54_003423"
     CDS             complement(12795..13454)
                     /gene="deoC"
                     /locus_tag="KNP54_003423"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBF0894283.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(13490..14677)
                     /gene="murJ"
                     /locus_tag="KNP54_003424"
     CDS             complement(13490..14677)
                     /gene="murJ"
                     /locus_tag="KNP54_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBF0894284.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(14754..15872)
                     /locus_tag="KNP54_003425"
     CDS             complement(14754..15872)
                     /locus_tag="KNP54_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBF0894285.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPKGRILNATISKEPSGR
                     YYVSLCCIDVDIEVFENTNNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKN
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         5684 a         2317 c         1905 g         5992 t
ORIGIN      
        1 acttggtact aatcttgaca aattgtccac aaaaataaat tatatatttt attattgttt
       61 taaattttta taaaaaatca gtattattga tactattgaa gttaaaaagc attaatttct
      121 aaaaacatca taatttttct aatagactta atcactttta atatatatag taaaacaaaa
      181 aacttatatt ttataaatat cataattttt ttactgatat tttattatat aaattttata
      241 gaattaattg tcaatttttt atgaaaatgg taagatattt atggatggta tcttgttata
      301 agaactatac tttaaatgtt tttaattatt ttgtcttatg taactcatat cctcaggaat
      361 gagattagaa attaagatgt tgtatcacaa agtggaggtg atactattaa aataggcttt
      421 attggttctg gaaaagttgg aacatctttg gcaaattatt ttttatcaaa aggttattgt
      481 gtttcaggct tttatggaag gaatcaatta tctttattag aatcaacaaa tttaacaaaa
      541 acaaagattt acagcaattt gaaagatata atttatgaaa acgatatatt atttattaca
      601 acatcagatg attctattga aattatagac aaaaaacttt ccaaatttaa tttaaaacat
      661 aaatacattt gccacacaag tggctcttta aaatctagta tattgttctg ttcaaaaaaa
      721 gcaggtgcat taatttattc tatccatcct atatttgcat tttccaataa aaatactgac
      781 ataaaaaaaa tgaaagacat ttgtttttcc atagaaggtg ataatgaaca agatgattta
      841 gttattcaaa atttcataga tgatttggga aaccaatttt ttataagaga taaggatact
      901 tcatccactt atcatttagc taatgtttta gtttcaaatt tagtattatc tttactagat
      961 ataggagtaa gttactttat taaattaggt ttatctgaag aggaatcttt aaaagctatc
     1021 agtcctttag taaaaaaaaa catagaaaat atacttgata atggctttac taaagctctt
     1081 actggtcctg tttctcgtgg agatataaca ccaataagga aacatctatc tgtattggat
     1141 aaaaaagatg aggatattta caaaatacta tccttaaacc tactaaaaat aattgcctta
     1201 ggaaatgaca attcattaaa aggtataaaa aatattacta tagaaaatgc aatcgaaaat
     1261 ttaataagta aatctgaaaa atacaaagaa atttacaaac ttttaggagg aaaaaacgat
     1321 gaaaaatacc atacagactt ttaagaatgc taaatatgaa ggaaaaaaac tatctatgct
     1381 tactgcttat gactactcaa ttgcaaaaat aatggatgag tgtgatataa atggtatttt
     1441 aataggagat tcattaggaa tggtcataaa aggtgaagaa aacactctat ctgttaccat
     1501 agacgaaatt atatatcata caaaagctgt aaaaaatggc gtaaaaaatg ccttaatcgt
     1561 aagtgatatg ccttttctat cttaccatgt ttctatagaa gatgcagtta aaaacgctgg
     1621 tagacttata aaagaaggag gagctcatgc tgtaaagtta gaaggtggct caaacgttat
     1681 aaagcaaata gaaagcattg taaatgctca aatacctgta atggggcatt taggattaac
     1741 tcctcaatca gtaaattcat ttggtgggtt taaggttcaa ggaaatacca gtgaaacagc
     1801 aagacaactt attgaagatg ctaaattaat agaaaaagca ggtgcattct ctattgtcct
     1861 tgaaggagtg cctacgaaaa tagctgagat ggtaactaat tctatttcaa ttcctacaat
     1921 aggtataggg gcaggaatta actgtgatgg acaaatttta gtttatcaag atatgttggg
     1981 aatgtttgga gattttgttc ctaagtttgt aaagcagtat gcaaatatag gagatataat
     2041 aaaagattca attaaaaatt acatcctaga agttaataca ggtgcatttc cacaagaaaa
     2101 acacagcttt tcaataaatg aatctgagtt agaaaaatta tactaatatt aaggatggta
     2161 caaaatgctt gtaaaagaaa ttaaattact aagaaatata atcaaagatt ggagaaaaca
     2221 tggctattct ataggccttg ttacaacaat gggattttta catgaaggac accaaagtct
     2281 tataaaaaaa gctgtaaaag aaaatgataa agtagtagtg agtatatttg taaatccaac
     2341 tcaatttgga ccaaatgaag attttaatag ctatccaaga gatatagata aagattttaa
     2401 atattgtatg gatagtggag caacagtagt ctttaaccca tcaccagaag aaatgtattt
     2461 aaaaggtaat tgtactacca ttaacgtttc tggacttaca gattttcttt gtggagctaa
     2521 aagacctgtt cattttggag gtgtctgcct agttgtttca aagtttctaa atatagtaac
     2581 acctgataaa gcttattttg gagagaagga tgcccaacaa ttagctgtaa ttaaaagaat
     2641 ggtcaaggat ttaaacatag atacagaaat aataggctgt cctataattc gtgaaaatga
     2701 tggattagca aaaagttcga gaaatacata tctctctgag gaagaacgaa aatctgctct
     2761 aatattaaat aagagcttaa gtttagcaaa agaagaatta gtaaaaggca atctaaatcc
     2821 agagaatata aaagaattaa taacagctaa aataaattct gaacacttag caaaaataga
     2881 ctatgttgaa attgtagata gtgagacatt acaacctgtt aagcaaatag aacattctat
     2941 acttgtggca attgctgtgt ttataggaaa aaccagacta attgataatt ttacatttga
     3001 gttaaatata tagtctataa ttttatataa tatatctaaa aaataataga atacctaaaa
     3061 agtaataaat tacctaaaaa ataataaatt gcttagaaaa taatagatta caataactaa
     3121 aattttaaaa ttaaattcct taaaagtatg attaattata attatataag tatattctta
     3181 ttacacttat attaatttat attaaatatc tactaactca aatattcata attaaacttt
     3241 aaactggata aattttcttt taagaatgaa agtttatcca gttttgcgat tataataacc
     3301 agttttacat atccacttgt aaaatatatc taagcaatat atcatactat atagatttat
     3361 gagtgaaata atatctgcta tttactgaat atttttattt ttcgtttttt agggggatta
     3421 gttgtgttta aagataagat tgatgaatgt gttcatataa tgactgcata tattgctagt
     3481 ttaaaagaat actattcatt catagaaact caaattggtg attttattaa aaaatatgga
     3541 gaagatgttg tagagttatg tctccataga gtgatgattc tactatgcga atgtggtttg
     3601 gcataaaatt aaatttatta aaatgggtaa gaagaatcct atataatatt cttcttaccc
     3661 attttaatat atcaatttca tagcttatcg tttaaaatat tttacatcca ttactagaca
     3721 actttacatt ctctttttaa ttctagtata tttaaatcat tttagttgct ccttatttat
     3781 tcttattact tgttttattt ataaaataat tctttttaat aatgtttttt gttgatattc
     3841 ctatcacaca tccaattatt tatcattgtc ttgaaattgt ttgcatactt aatttaatcc
     3901 aattgaaaca ccccagcata gaatcccctg taaaatagaa gttggattaa atcctaacat
     3961 ctatacagaa aatactactc caagcacaag caatataatg gaatatattt atcacttaat
     4021 tttttatact ttttaaatcc catacctaaa acattaagtg cagctattag aattaataat
     4081 tgttgtggta taaaattatg cttgcttcat atttattcat tttttgctat aaaagttctt
     4141 gttttacaaa aaacatttgt tttgtatcaa aataatactt ataaattaca taattctcat
     4201 aaaaatttct agtattactt gtactcttaa taaataatag ccaacaagta ccttaaatca
     4261 ttatatctat atctaataag aaacacagta agataatctt ttcgcccata acttaataaa
     4321 aactgttgat attagtagca attgaattta gttaatttat ttataatata cataaattta
     4381 aatattacga ataaagtatt ataaatagga tactttctaa ggggaggaaa ttatgataga
     4441 taatcaaaaa tatgttattt tatcactaga attacattta tttttttcaa gaattatgaa
     4501 agagcatgct ctttttttag aagcaggatt cacaaataaa aattataatc ttgctatgga
     4561 agctgaccac tataaaaagc aatttgaaga tttattatca tacactgtta gtgctagtaa
     4621 tggtataatt agacctgata tattatattc agaagagctt gtaactactc tcacatcagt
     4681 tgcagaacaa aaaacagaag agtttacagg gatagaaata aacaaaaaca tcactacaag
     4741 agaattaaat ctacaaagtg gtgtaaaccc acaagttggt caagacttag tgaactatgt
     4801 agctcaactt aactctgatg caataagatt acttgatggg cttattaatt ttaaagaaag
     4861 agtcttagat ggtgtactat catgtactat atttacatca aactaccctc tacttcttga
     4921 acatataata catgaagcaa atttatatcg ttcttatgta gttgaccttg aaaataaaat
     4981 agatattgag tcaaaaaacg ctaaagaaat agaattattc tgggaccata ttatgatgga
     5041 acatgctctg tttatgagag gattactaga cccctcagaa ggtgaactaa taaatacttc
     5101 aaatgatttt gctataaaat ttaatgaatt aattgaaaaa acaaacgaaa tgactgattc
     5161 taatatcaag aacattacag aagaaactct aaatgaaact gttgagttta aagattttaa
     5221 agaagcagga gcatcaggaa tagaacagtg taagataaaa tctataatat taccactttt
     5281 agcagaccat gttttaagag aggcaaatca ttatattaga atattggaga gttataaaaa
     5341 catgtaatta aaaattactt ttaaaataat ctttgcatat ttagataaaa taaaggtaca
     5401 gttaactgta cctttatttt ttataaactt ataaaattta aacaagttat tcataaaata
     5461 aaataataat catctataac ccacaacttt attttatatt aaataaaaag tattagtggt
     5521 tatgttttat aagtatttct ttattcagtt atttattaaa aactaatagt aaatcttata
     5581 ctaatcgcat atttatgtta taactatatt gtaactattt tcgtaatctt aggaaaagat
     5641 tacttataaa attaacctta tacaataata tatcgtataa tcttaattag cataatagtt
     5701 acaatattaa aatttaaata tgggagtgat tttagtatga taagacaaac accattagag
     5761 aaacgatatg acaagctagg tcctcatatt gtaacagcac tcaaaaaacg ttattttgat
     5821 gcttattact gtaaaactag aaatgaagct ttgcaacaaa ttttagattt aattcctcaa
     5881 aatcatgtag tatcatgggg aggatctgaa acacttaaag aaatgggcgt acaaactgct
     5941 gttagagaga aaggatttaa agttattgat agagatttag caaaaactcc agaagaaaga
     6001 actgaaatta tgcgtcaagc acttctatgc gatacttttt tgatgagtag caatgcaatt
     6061 agtgaagatg gacaactctt taatattgat ggaaatggca atcgtgtagc tgcaatgata
     6121 tttggtccaa aaaatgttat agttgtagct ggtatgaata aaattgtaaa aaacattgat
     6181 gatgcaatac aaagaactag aacaattgca tctccagcag ttgttcagcg ttttcaagat
     6241 gtcaatacac catgctatat taatggaagt tgtatagatt gcacaagtcc tgaaagcatt
     6301 tgtgcataca tggttactac aagaatcagt cgtccagcaa aaaaaataaa ggtaatattg
     6361 gtaggagaaa atcttggtct ataaaatata catacatgta aatagctcta taaataataa
     6421 aatcatatga aataacttat ttctaaaagt ggtagaataa aagcttctac aagactttca
     6481 ttctgccact tttatattct tttaatttgt gtttctatat tattaattgc tccaattttc
     6541 atatatatta ctaactattt ttattttcat aatttttttg ttcttcatca agctgtttat
     6601 aataatcttt attatagtca gctagataat ctataccacc tcctgtaatc acatttaata
     6661 atttcattgc agattcttga ttaactttac aaacataatt atcaccagat ttaacaagct
     6721 ctaatgtaat attaaattct tttttctttg cagaatcaat atctttcata gttggatttg
     6781 gcatcatttc tcctagttta ggaggattct tttttaaaat agaaaccata tcagtattgt
     6841 taatttttaa atctacagtc actttatcct tattattttt tatatctgaa atttcccaag
     6901 tcatattttt agaatacatt ttaaatcctt ctttatcttc gtatataaga ttacctaacc
     6961 ctgattttgg gaaatactta tcaacagtat ctgcatcttg tgtttttatt gaattaaaca
     7021 tactatccac ttcatttttt atcttattat cattagtaca accagctaac accagtactg
     7081 atattgcaaa cattataata catagaataa atttcttcat taaattatat ccccctatac
     7141 ttttttgcac aaatattatt ctctttttta tcttttgaaa aagttgtagt aattgcattt
     7201 tgtggacaaa cttttataca ttcaccacac ctaatacagt ctggactatt tacatcttta
     7261 tatattggta tatcaagctt acattttgtt tgacatgctg tacaatttgt acatttatct
     7321 ttatcaattt taaatctata tattgaaata ggattaaaaa aaccatagat tgctcctaaa
     7381 gggcatatat acttgcaaaa tggcctataa gtaatgattg acatcaataa tatcaataac
     7441 aaaatactta acttccagct aaataaaaat cctattgatt ctcttaaatt ctcatttcct
     7501 aaaataagtg gtattcctcc caaaagtgtt cctgaagggc aaatccattt acaaaaccaa
     7561 ggatttccac cccctgctac atttacaata gcaactggca aaataattac aaatattatt
     7621 aagactatat actttagata ttttagatat ttatcaccat aaactttttt tatctttact
     7681 ggaaagggta ctttatgtag taaatcttgt acaagtccaa agggacaaag ccaaccacaa
     7741 acaaatctgc caaaaaaagc accaaatgcc attaaaaaac caacaacata aaatgagaat
     7801 ttatactctc tgcttgataa aactgcttgt aatgaaccta ttggacatgc tccaagtgca
     7861 cctggacatg aataacaatt caatccaggt acacataatt ttttactttc tcctccatat
     7921 atagttcctt ctaaaaatcc atttacatat ccatttgtta atgctgtaaa tgcaacttga
     7981 gtaataagtc ttatattatt atttacttta gataataact tcattcctct tctcctaacc
     8041 aataccaata cactcaagac aaatcataat tgctttagtt aatactgtat ttgtttctcc
     8101 acgatatgta cctaatgcaa taaatataat actaattgca ataatagaaa tgcctttttt
     8161 attatcttta ataaagttac tcattggctt ttaccatttt tagtctttca tctataattt
     8221 ttttccaatc ttccttacta tttgcaccta caaccttctc acccacaaag tttcctttct
     8281 tgtctacaaa ataagttgtt ggaaactcca taactctttt aaaatcagtt tttttaagtt
     8341 cttcagatac agtcaattgt tggtaagttg catctgactt tttcataatg tctttaacta
     8401 aatttttctc ttcatttgaa agaccagttc tcatatcagt tttatcaact tctacaacta
     8461 atccctttat agctacattg gaattattac tctcatattc ttttgataat gcttcaagct
     8521 ctggcatttc acccacacat ggtccacacc aagtagtcca gacattaata agagtaagtt
     8581 ctttatttga aaatatctct tttgttacct tatttccatc aacatcctcc gtatctaaat
     8641 tactaaacca ttcactatta ttcttgtttt tttctactgg cttagattct tttttgctac
     8701 atccagaaat catacctaaa acacaaatac atcctaaaac tactatgaaa aaccttttca
     8761 tatctcacac tcctagaatt tatatagtat ataaaatcgc tgcttgaaat aaaaataact
     8821 tatcttctat attaaagtaa ttatatttaa taaataagag ctaatttaaa aaaagatata
     8881 cagttaaaat ctatttcttt tcagacaaaa tcttatatat atataatagc ttgtaaatct
     8941 taagattata tacatatatt tctaaagatt ttcttaagaa acagttagat tttactaata
     9001 taagtttatt aattagcatt atactaattt atcttaatat gattttttgt tgattttaag
     9061 ctgtttatcg tataaataaa atttttcttg actatatagt tactatatag cttattatat
     9121 atagagagta ataaaaggag gtaaaattta tggaaaattt atttacaaga aaattcacta
     9181 cttttgaatt tctaaaattt gtttctcctg caattatatc catgatattt atatctttgt
     9241 acacaataat agatggcatc tttgtatcga cattagttgg ttctgatgct cttgctagta
     9301 taaatattgt actacctata attaaccttg tttgtggatt tggaataatg atggcaactg
     9361 gtggaggtgc tatcgtttct atacgtatgg gtgaaaatag acaggatgaa gccaactcta
     9421 cattttcttt tatagttttg ttttcattga ttgttgggat tttattcaca gtaatctcat
     9481 atttctttat caaagaaata tctattttgc ttggtgcaac agataagtta ttaccatatt
     9541 gtataactta tggtaaagtt atgattttat gtacaccatt ttatatttta aaatttatat
     9601 ttgagtactt tgcaagaact gatggaaatt ctaaatttag tttatttcta tcagtcattg
     9661 gtggtgtaac aaatataata ttggattatg tatttattaa atattttgga atgggtcttt
     9721 taggagctgc agttgcaact gctataggta ttattttaac ttgtgtttta ggtattattt
     9781 acttcttatc taataaatct acactaaaat taagaaaacc aaaaaccgat tttagactta
     9841 taagagatac tatgataaat ggttcttctg aaatggttac agaattatct acaggaatta
     9901 caacattctt atttaatgta gtagctttaa aattagcagg agaaaatgga cttgctgctc
     9961 ttactatagt attgtatgct cattttttaa tgacatcagt ctatctagga ttcgctgctg
    10021 gagtgtctcc attaataagc tataattttg gtgctgaaaa cagtgataaa ttaaaagaaa
    10081 catttaaaca ttctctaaaa tttatatttg tttcttctct tttagtgttt atttttgctt
    10141 tagtatttgc accatttatt gttagggtct ttgtaagtcc agataacaca gtatttaaac
    10201 tagccttaca aggattaaaa atatttgcat ttgctttttt gtttgttggt ataaatatat
    10261 ttgcatcagg attttttaca gcatttcaca atggaaaaat ttcagctatt atatctttta
    10321 gtcgtgcctt tgtttttata atcataggaa tcataattct tcctcctatg ttaaacatga
    10381 ctggattatg gcttacagtt ccatttgctg aggttataac catatttata tctattctat
    10441 ttataaaaaa atataaatgt agatataagt attaaaaatt aatacttaaa atcaacattt
    10501 attaaaacta ataaacctgc tttaaaatac aaatttacaa atttgatttt taagcaggtt
    10561 ttattttagt tataataagt catttgcata ctctttaatt ggtgcttttc taagtaataa
    10621 aattataaat attatgcaaa taactataat tcctactttt gttccaaata aaataaaagg
    10681 attctgaaat gaataaataa ttttttctaa atacaatagc attttatgca tatttttagt
    10741 tgcaaaatta actatataaa ttatcattaa tatcggtaat cctatcaata tagtaatact
    10801 agtaactttt ctaactctat atgtaaaagc tccaagtaac actcctataa aacctataca
    10861 tatttcattt atacatattt gtacaaaata atttaaataa gttagtggca tacttgatgt
    10921 tgaaggatct atcagtgctg atatagatgt ccaaatcata tctctcttta gtaaaactga
    10981 tagttctata ctgtaacctg ttataatttc tataaataac ttcgataaaa aaatcaaaac
    11041 tatacctaaa atagaaatca caaagcttaa aataattaaa tctatgacaa tagcttttat
    11101 acaacttttt ctatctgctc ttatacttaa agctcctgaa aagtctttat ttgctatatt
    11161 tactccatac acaaatagca gtatagttat atatgttaaa ataggattca caatcgtgga
    11221 taaattagtt ttagatgctt ctccaaaaat cttgagaata aacactggca aaatattcat
    11281 aacaattccc acaatcataa atataattat atacaattta gtatttttat taaaaaattt
    11341 tatatatggc tttaattcat tcaattacaa ttcctccttc ttagtcatgt taacaaacat
    11401 atcttgtagc cctatgtatc ctacatcaat atttgaattt ttaagtattt tttcatcact
    11461 ttcactaaaa tcaccatagt aaaaataagc aactgcattt ccaaatgcct ttttaggttt
    11521 tatatttttt atacattcta atttttctaa ctcttcttta tttccagtaa tataatgagc
    11581 tttttgtttt atgacatcaa tttcttcatc tataataatt tttccctcat ttaatattat
    11641 tacatgctcc agtaaatcat ctatttcatc aatcaaatga gttgatatta ttattgtcct
    11701 tggatttttt atataactat ctaaaattat gttataaaac tcttgtctat ttactgcatc
    11761 cagaccaatt gttggctcat caaatatggt gatagctgaa ttagaacaaa tacctattat
    11821 atttgaaagt atagttttca tacctcttga cagttgttta tacttttttt tagtatttaa
    11881 atcaaaatat ttgcataatt cttcttctaa gcctttatca taacttttat aaaaactaga
    11941 agaaaattca aatatctgac ctactttaaa atctggacta taaaattctt tttccctaac
    12001 gatacaaact tcttccaaaa cttttatatc ttcttttggg ttctttccta atatttctat
    12061 ctcaccttca ttttgaatta actgatttac cattatattt aataatgttg tttttccagc
    12121 tccattctta cctaataaac catatatctt atttttttca aagcttagag acatattatt
    12181 aaaaatattt tgcttcttaa aactgtgaga taaattttct atcttaatag aactactcat
    12241 atattaatcc tccttgaaat taattataat atcaaccaat tcttctctat ttatttctaa
    12301 tttgttagct tcttgaagta ggttttttac aaaattatgt ttaaaatttt cttttctagc
    12361 ttcttttata atagtttttg caccatctga tacaaacatc cctatccccc tcttcttata
    12421 taaaatattt ttatcaacca atatatttat accttttaat actgtagctg gattaatttt
    12481 ataaagcttt gaaagctctg ttgttgatgg aacctgttct tcttctttta ttccatttga
    12541 tagtatctca tcttcaattg ctcgtgctat ctgaataaat ataggttctt cattatttaa
    12601 tactaatttc ataggttcct cctttctcca tcagttagtt actcaactaa ttaactatat
    12661 aacttataat atcttgaaaa atattttctg tcaatactaa ataaaaaaca gagggaaaat
    12721 tccctctgtt ttttgttctt tatatttata attaaatttt gatttttgta atcctatccc
    12781 ataagttaaa aactttaata atctgttgta tcttcatttt ttaatatttt acatattgag
    12841 ctagttccta acctttctgc tcctgcctct ataaattttt ctgcatcaga aattgattta
    12901 actccccctg cagcttttat ttttacattt tttccaacat gctctttcat aagttttata
    12961 tcttctaaag tagctccacc tgttcccatt ccagtagatg tttttataaa atctgaacct
    13021 gacattgtta ctatttcaca catttttatt ttttcatctt catctaaata acatgtctct
    13081 ataatgactt ttaatacttt atctcctata gcttttttta tttcttttat ttcttttcct
    13141 atattatcat aatctttatt ttttatatct gaaatgttta caaccatatc aacttcatct
    13201 gctccatttt caatagcatc ttttgcttca aatacttttg tagcagtagt ttgatatccc
    13261 aaagggaacc ctatcactgt acatatcttt attttacctt ttagatattc tgatgctctt
    13321 ttcacatatg atggtggtat gcaaactgat gctacactca tatctacagc ttcatcacat
    13381 aaaattttaa tatcttccca tgtagttgta gcttttaaaa tagtatggtc tactgttttt
    13441 aatatatgtt tcataaaatc ctcctaaatt tataattaat ataattagat tactttttta
    13501 aatgcaattt tctctttgca atgtttagta tcatatcaac ctcttcaact ttaaaaataa
    13561 tcattagtag tgtataaatt ccacctccaa ctataactga aatagctagt gatacaaact
    13621 cattaaatgt tcctactccc aaaattccaa atataaattt atacgtaaag tatgataaaa
    13681 cacccataat taaagatgca actaccgatt tcaaagttgc ttttattatt ttatcttgtc
    13741 caaaatatcc aacttttctc tttaggttca agaagagtaa caatatacat gcaattgatg
    13801 atgaactagt tgcaagagca agaccaccat gagccattgg ttttattaaa actaagtcca
    13861 atactatatt tacccctaca gatataatcc catttaccat aggtgttttt gtgtcttgta
    13921 atgaataaaa aacctttccc aaaatatctc ttaagccaaa tgcagtcata ccaactgcat
    13981 aaaaaattaa ggcagttgct gtcatttggg ttgccctcgc atcaaaagca cctctctcaa
    14041 aaatgattct aacaacagga gttgcaaaaa aaatagaagc aactgaaata ggaatcatag
    14101 aaattattat catatttata ctggatttaa ctgaactagt aaacttcttt tgattatttt
    14161 ctgcacttaa cttagataac ataggataca taacagatac tattgaagct gtaaatgtcc
    14221 ctgtaacaaa accatttaat ctatctgcat aagtaagtgc tggaatgctt cctttaacta
    14281 atgttgaggc taaagttgta tctaccaatg agttcacttg attaacagca acacctataa
    14341 atactggtga aagtaatgct agtaatttaa taaggctatc atctttaaag tttaagtagt
    14401 ataagtattt gtagttcgtt tttttaacaa aaaacatgta aaagagcagt tgaactacca
    14461 tagcaaccac agcaccaatt ggaagtatgt atggtccaaa tatggtactt aacattattg
    14521 aaataattat tactatatta tagggtatac ttccaaatcc aactacaata aagttctctt
    14581 taatttgtaa aaatgctgac ataacactcg taatacctat gaatattatt cctgttctga
    14641 acctcccatg actaaagtca cagggttcct gcttcataga attttgcata ctaaaatatg
    14701 tcttactaat tctccacagg ctatccccgt agttcctacg gttcttacat acgttattta
    14761 ttttgaattg ttattagtct taatccttct tttaatatat ttatacttgc atttatatct
    14821 ctatcgtgag tttcattaca actaggacaa atccattctc ttatatttaa gttcttaact
    14881 tcctcgtttt tatacccaca tttattgcat atttgtgaac ttgcaaagaa tttacctacc
    14941 tttacaattt gtctaccata ccaattagcc ttgtattcta attgacgaat aaactctgac
    15001 catgatacat cagaaattaa gcgagatagt ttacgatttc taatcatatt ctttacttgt
    15061 aaatcttcta tgcaaataat atcgttctct tttattaatt tagtagatag tttttgtaga
    15121 aaatcatttc tttgattagc tatatgttct tgaagtcttg caacttttaa tcttgcttta
    15181 tttctattta aactaccgat tgtttttctc gataattctc tttgtaattt agcaagtttg
    15241 tttaatgact tcttaagata cttaggattt tctataaatt ctccacaact tgagatacaa
    15301 aattctttaa ttcccaaatc taaacctata tgattattag tattttcaaa tacttcaata
    15361 tctacatcaa tacagcataa tgatacataa tatctaccac ttggttcttt agatatagta
    15421 gcattaagta ttctcccttt aggtacttgt ttatccctta tcttaaccat accaagttta
    15481 ggtagtttta tatgttgacc acaatacata atgtttccat ttgtaaagtt agttttatat
    15541 gaaaatctat taattttctt tgatttaaat ttaggaaatc ctgctttttc tttaaagaat
    15601 tttttatatg cattatctaa atcttttaag gcgttttgta gtgaaaattt gtcaggttct
    15661 ttaagccatt ttaattcttt ttttaaattg gtcaaatcag aactacactg tttataagta
    15721 aaagtttctt tatcgttttt ataaacatct attcttttag caagatactt attatataca
    15781 aatctacaac atccaaaagt tttgttaatt aactcttgtt gttttttatt tggatacatt
    15841 ctaaacttat aagctttttt cactgctatc acctcacttt aattgttttt tgatacac
//
LOCUS       DAEHWO010000098        14951 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEHWO010000098 DAEHWO010000000
VERSION     DAEHWO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14951
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.100"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            89..655
                     /locus_tag="KNP54_003426"
     CDS             89..655
                     /locus_tag="KNP54_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBF0894286.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            960..1421
                     /locus_tag="KNP54_003427"
     CDS             960..1421
                     /locus_tag="KNP54_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0894287.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1489..3735
                     /locus_tag="KNP54_003428"
     CDS             1489..3735
                     /locus_tag="KNP54_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894288.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3728..5560
                     /locus_tag="KNP54_003429"
     CDS             3728..5560
                     /locus_tag="KNP54_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894289.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6279..7556
                     /gene="hflX"
                     /locus_tag="KNP54_003430"
     CDS             6279..7556
                     /gene="hflX"
                     /locus_tag="KNP54_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBF0894290.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7789..8286
                     /locus_tag="KNP54_003431"
     CDS             7789..8286
                     /locus_tag="KNP54_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0894291.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8336..8860
                     /locus_tag="KNP54_003432"
     CDS             8336..8860
                     /locus_tag="KNP54_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBF0894292.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            9172..10536
                     /locus_tag="KNP54_003433"
     CDS             9172..10536
                     /locus_tag="KNP54_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBF0894293.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            10675..11841
                     /locus_tag="KNP54_003434"
     CDS             10675..11841
                     /locus_tag="KNP54_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBF0894294.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            11958..12740
                     /locus_tag="KNP54_003435"
     CDS             11958..12740
                     /locus_tag="KNP54_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBF0894295.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(12859..13512)
                     /locus_tag="KNP54_003436"
     CDS             complement(12859..13512)
                     /locus_tag="KNP54_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0894296.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(13536..14900)
                     /locus_tag="KNP54_003437"
     CDS             complement(13536..14900)
                     /locus_tag="KNP54_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBF0894297.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         5796 a         1660 c         2538 g         4957 t
ORIGIN      
        1 ataaatataa attaaattat atgtgtatat attgtacttt aatagtgata taataataaa
       61 aaaattttta aagagggtga tattacatat gagaaaactt gaagagatat tagaatataa
      121 taaatcattt gtagagaaca aagaatatga acaatatgtg acatcaaaac atccaaataa
      181 aaaaatagta gtcttatctt gtatggatac aagattaact gagcttttgc ctaaggctat
      241 gaatttgaaa aatggagatg tgaaactaat aaaaaatgca ggagctacta taatgcatcc
      301 ttttggaagt attatgagaa gtgttttagt tgcaatttac gaatttgatg tagatgaggt
      361 tatggttgta gggcatcatg gatgtggtat gtgtaatgtt gatacggata agttacttgg
      421 taaaatttta gatagaggaa tatctaatga tgtaatactt acacttcgta gtgctggaat
      481 tgatacaaaa caatggttac atggattcga ttctgcagaa gaatctgtaa aagatagtat
      541 tgatttaata aaagggcatc ctttaattcc agatggtatt attgtacatg gtctaattat
      601 atcacctgaa actgggaagt tagacgttgt tgtaaatgga tatgaagata agtagagtat
      661 cataatgtta tataatcaag atactgttga atatgatgtt gtttcaaaat ttattttggg
      721 acaacttttt tatttgaaaa tatatgaaaa ggtttatttt aagctttaca ataaaaaata
      781 taagtagctg actaattaaa aatcttacta ttatttatta aaattataac tatatgatat
      841 aaaaatattt aataaatgaa atttatatga attttttata aatatattga aaaaatgcat
      901 gcagtatagt aaaataatgc ttagccgact aagtaatata aaaaataagg agggcaagta
      961 tgaatagcaa ttctgaagaa aaattaaatg atgttttctt gcaattaatg cgaatatatt
     1021 ttataagaac tcatttttat tttgataaat taggcttata tcatggtcaa ccccaaatac
     1081 ttttttcttt aaagatgaaa gatgggcaaa gtcaaaaaga attagcagat aaaaggaaag
     1141 taaaagcatc tacaactaca gttatgataa agaggatgga aaaagctgga cttgtggaaa
     1201 gaaaacaaga tgaaaaggac caaagagtat ctaggatttt tttgacagac aaaggtttag
     1261 aaatatgtaa taaagttgaa gaatttaaca aggaattgga aagagagttt tttttaggat
     1321 ttagtgaaga agaaaaaata gtacttagaa gacttctaat gcaagtacga gataatttaa
     1381 aagcaggatg tcataagcat gaagatgaaa aatattttta aagtttaaaa taatgttttt
     1441 caatttaatg ttattagact aattaatatt acagaaggga agaaatgtat gtttaaatta
     1501 attaaatatt taaagaaatc ggcattatca atagtaataa tagtctgtct attggtaatt
     1561 caagcggtat gtgacctttc tttaccagaa tacacatcca atatagtaaa tgtaggtata
     1621 caacaaggtg gagtagaaaa ctctgttcca tctgtgatta gagagagtga attaaataaa
     1681 attactttat ttatggataa aagtagtaag gataaagtac tagataatta tactttgctg
     1741 aataaaaagg attatgttaa gtataaagat aagtatccag gtctaaaaga tgaatctctt
     1801 tatgagttaa atactaaaga caaagacact atagatgatt taaatgttat ttttggtaaa
     1861 gctattttaa tagtatcagg gcttgagggc gatagtaaag aggtaaaagc tatgaaagct
     1921 cagttaatga gcaaacttcc accacaagct actcaaagtg gagatgttga tatatttaaa
     1981 ttgttatcag caatgccaaa ggaacagtta gatacattga ctaaagagat gagcaaaggc
     2041 tttgaaagta tgccagagag tatgataaca caaagctctg tttcatatgt aaggtcagaa
     2101 tatgagaaaa taggtattga tacagaaaaa actcaaaata attatatatt atttactggt
     2161 gctaaaatgc ttggtatagc aatgattagt atggtagcta caataacagt aggattttta
     2221 gcagcaagag tagccgcaag tgtaggtaga aatttaagaa gtggagtatt tagaaaagtt
     2281 atgtcatttt caaatactga aatgaatgaa ttttctacag cttcattaat tactcgtagt
     2341 acaaatgata ttcaacagat acaaatgttg atggttatgt tgcttagaat agtattctat
     2401 gcacctataa tggctatagg tggagtgata aaggttttaa acacaaatac ttcaatggcc
     2461 tggattatag cagtagcagt agttgctatc ttatcattaa ttgtagtgtt attctcagtg
     2521 gttatgccta agtttaaact ggttcaaaag cttgttgata agttaaactt agtaagccgt
     2581 gaaataatta ctggtattcc agttatcaga gcttttagta ctgaaaaaca tgaagaagaa
     2641 agatttgata aagcaaataa aaatttaact aaaacaaatc tttttgtaaa tagagttatg
     2701 acatgtatga tgcctgctat gatgcttata atgaacctta tcacagttct tatagtttgg
     2761 agaggtgcat acagtgttga ttctggagca atgcaagttg gagatatgat ggcatttata
     2821 caatatacaa tgcaaataat aatgtcattc ttaatgatat caatggtatc tattatgctt
     2881 ccaagagcat ccgtttcagc tacacgtata gatgaagtat tagtgtcaga tataagcata
     2941 aaagacccag aaaaatcaga ggcacaagag tttaaggaag ataaaaaggg tcttgttgaa
     3001 tttaaaaatg tttcgttcat gtatccagac gcagaagaac ctatattaac aaatatatct
     3061 tttacagcaa agccaggaga aacaactgcc tttataggaa gtactggtag tggtaagtca
     3121 actcttataa atttaattcc tcgtttcttt gatgttactg aaggagaaat attacttggt
     3181 ggagttaata taaaaaatgt ttctcaacat gatttaaggg aaaaaattgg atatgtacct
     3241 caaaagggag tattgttttc tggtactata gaatccaact taaaatatgg tagaaaagac
     3301 gcaacagatg aagaaatgag aacagcagct gaaatagctc aagctacaga atttatagat
     3361 tctaaaccgg aagcttttaa aactgaaatt tctcaaggtg gaacaaatgt atctggaggt
     3421 caaaaacaaa gactttctat tgcaagagca atagcaaaaa atccagaagt ttatatattt
     3481 gatgatagtt tttcagcact tgacttaaaa actgatgcag ctcttcgtaa ggctttaaaa
     3541 tcaaaaactg ctgaaagtac agttctaata gttgcacaaa gaattagtac tatcttaaat
     3601 gcagaacaga taattgtttt aaatgagggc gaaatagttg gaataggaac acataaagag
     3661 cttctaaaaa attgcgaagt ttatgagcaa atagctttat cacaactttc aaaggaggag
     3721 ctagctaatg agtagaatgg gaagaggtcc tatgggaaaa tctatgggag caggacaaaa
     3781 agcaaatgac tttaaaggga ctatgcgaaa actaattgca tatttatcta aatttaaaat
     3841 atcaataatt ctagtaattg tatttgctat tggtagtgcg tcgttttcta tagtaggtcc
     3901 aaaaatttta ggaaaggcaa ctacaaagat atttgaaggg ctagtgagta aagtttctgg
     3961 aggaaacgta ggtatagatt ttaatgcaat tggaaaaatc ttaacctttt tacttttcct
     4021 ttatttgata agtgcactgt tctcttttat acaaggattt ataatgagtg gaatttctca
     4081 aaaagtatcc tataatttaa gaaaagagat ttcagcaaaa ttggatagat tgccaatgaa
     4141 gtattttgat actaagacgc atggtgaaat attatcgaga attacgaatg atatagatac
     4201 tttaaatcaa agtttaaatc aaagtatgac acagcttata acatcagtaa caactatgat
     4261 aggtgttttg ataatgatgt tatctataag tggaattatg acattagtgg cagttttaat
     4321 attaccaata tcaatgtttg taatttcaag aataataaag aaatcacaaa aatactttag
     4381 atatcaacaa gaatatttag gaaatgtaaa tggtcaagtt gaggaaactt acagtggcca
     4441 aacaatagta aaagcattta atcgtgagga tgaagtaatt gaagagtttg ataaactaaa
     4501 tgatagcctg tataattcag cgtggaaatc tcaattttta tcaggtataa tgcaaccact
     4561 tatgatgttt attggaaact tgggatatgt aatggtatca atcttaggag gttggcttgc
     4621 aattaagaaa acaattgagg ttggtgacat acagtcattt atacaatatg taagaaactt
     4681 tacacagcca atgactcaga ttgcacaggt tgccaattta ttgcaatcaa cagcagcagc
     4741 ttctgaaaga gtatttgagt ttttagaaga ggaagaagaa gtccaaattg ttgaaaatgc
     4801 agtttcaata gatggtttag aaggtaaaat tgattttgaa aatgtcaact ttggatataa
     4861 cccaaacaag actataataa atgatttctc agtaaatgtt aaacctggtc aaaaagttgc
     4921 tattgttgga cctacaggag caggtaaaac tacaatagtt aaactgttaa tgagatttta
     4981 tgatgttaat agcggttcaa tactgattga tggtcataat attaaagatt ttaatcgtag
     5041 tgagcttaga gaaatgtttg gtatggttct tcaagataca tggttattta gtggttcaat
     5101 tatggaaaat ataagatatg gtaagttgaa tgctacagat gaagaagtta tagaggctgc
     5161 taaatctgca catgttcata gatttattaa gacattacca gatggatata agatgaaatt
     5221 aaatgaagaa gcaagtaatg tttctcaagg tcaaaaacaa ttattgacta tagctcgtgc
     5281 tattttagct gatcctaaaa ttttaatatt agatgaagct acaagttctg tcgatactag
     5341 aacagaagta ttgattcaaa aagctatgga taatcttatg gaaggtagaa caagttttgt
     5401 tatagcccac agattatcaa ctatacgtga tgctgatatg attcttgtaa tgaatgaagg
     5461 agatatagtt gaacaaggaa atcacgagga acttctaaag aaaggcggat tctatgccaa
     5521 tctttacaat tctcaatttg aagaagatga agcaatgtaa caaaaaacta tcttagcata
     5581 gacatgtaat taataagata aaataaatga gggtgcctta aaatgaactt tttaattcat
     5641 aaggcactct tttgtgtatg aaataaagtg tatttttatc attttaacaa tgaaaaagag
     5701 gattctctat attttgagat agccacataa ttttatgtct ttacaaagtg tttattttat
     5761 tataatatgt agtaaggaaa atgttggagg tgattatcaa aatgtatatt taattttatt
     5821 ctttaaattt tattataaat agaatttaat tttaatagtt gatgattata ttgaagtata
     5881 tgtttttatt acttttatta atcatgcaaa taactactta aatttaagaa tagggttaaa
     5941 tataaaatga taattacata taagttaatt aaactaatgt atttttaata tatatttaga
     6001 attttaatcc ttcttatgat ataagtagct tgttttgtat tacttagatt tgtaaggagt
     6061 ttttttattg aaaaaactgc ataatatatt tgggaggagg tgtaagaaag tgatttttta
     6121 tataagattg agaaaataat gcacgattat ggttattata atagtaaata agaagtgtca
     6181 tttaaggata agataaaaag caaaattctt gatgaattta attatagagc cataatctcg
     6241 tgctatagat taaataaaaa atagcagata aggagaatat ggatatggcg aaaaaaggaa
     6301 taacagtagg attaaacata aataataaat ctgaggactt taatgaacta atgattgaac
     6361 ttgaaaactt atgttcagca tgtgatattg atgttgtagg gagtataact caaaatgcaa
     6421 agcaggttaa tagagcattt tacattggga caggtaaagt tgaggaaata ttaaacttaa
     6481 taaagaaaga aaatatagag atagttatat tttacaatga actttctaca tcacaactaa
     6541 aaaatcttga agaaaagctt aattgtgaaa ttatagatag aacggcattg atacttgata
     6601 tatttgcaca aagggcaaaa actagagaag ctaaacttca agtagaagta gcaagtttaa
     6661 aatatatgtt accaagactt ataggttcaa atgaaaattt aggacgtcaa agtggtggag
     6721 ttggtactaa aaatagaggt tctggtgaga aaaaattaga acttgaccgt agaagaatag
     6781 aagaaaagat aacatcttta aatagggagt tggatgattt aaaattccaa agagaaactc
     6841 aaagaagtat gagaagaaaa tcaaatcttc caaatgtagc tctagtcggg tatacaaatg
     6901 ctggtaaatc ttcaataatg aataaactag tagatatatt taaaaactct gaagaaaaga
     6961 aagtgtttga gaaaaacatg ttatttgcta cacttgaaac ttctgtcaga aatatagttc
     7021 ttgcaaataa caaagaattt ttattatctg atactgttgg ttttgtaagt aatctaccac
     7081 atgacttagt aaaagcattt aggtcaacat tagaagaagc atgtgaggca gacgtactgt
     7141 tacatgttat tgatatttca aatccaagct ataaaagtca tattaaagtg acagaagata
     7201 ctttaaaaca aataggtgca gatggtatac ctatgataca tgtgtataat aaaattgatt
     7261 taatagatgt agaagtattg gatagaattt tagatagtat cgataaagaa ggtatatttg
     7321 tttcagttaa aaaagatata aatatagata aaatgataaa atgtatttgt gatagcatat
     7381 ttaaagatta tgtaagatgt aagttcttaa ttccatatga taaaggtcat gtagtttctt
     7441 attttaacga aaatacgagc attataaata cagaatacag agaagatgga gctattttag
     7501 atgtagaatg tagcaatata gaatataata agtataaaaa gtatgcttta gagtaaattt
     7561 tgaaaaactt attatagcct aaaatatatt taatttataa tttattataa attgattgta
     7621 aatatgattt tatgaaacgg tatagccata atgctatgcc gttttgccgt ttataataaa
     7681 aataaattta ttgacataat agtaactaat tactataata taaagtaatt agttactatt
     7741 taaaattatc aaaaaattaa aatctaagat aaagagaagt gtataataat ggatgcagaa
     7801 agtttaatga aaaaatatat ggtagatgat gatagtagaa aacaagctat atttgcaagt
     7861 atatttgtaa tgcaaaataa acttcaaact acatgtgata aattagaccc agaattaaca
     7921 atgaaacaat ggttactttt agctattgcg gactctgtag atgaaactct tacattaacc
     7981 aaacttggag aattaatggg gtgctcaaga caaaatgtaa aaaaactagc tattgcttta
     8041 gaaaagaaag gttttataca aattgagcag aatgaaaaag attcaagagc tatctgtctt
     8101 gtgacaaaag atagagtgca agagtattct aaaaaagtaa gaggtatgca ggaaaaagta
     8161 ttacagcttt tatttgaaga ttttacagag aaagaagtgg aacagttatt ttttggaatt
     8221 atgaaattaa gtataggaat tgaaaatgtg aaaaattatg tagaaaataa tgacgttgga
     8281 gaataagcaa gtatcaaatc aactttgtat gacatcagag agggggataa tttatatgaa
     8341 aaatgtagta gtgatttata agagtaagta tggttcaaca aaaaaatatg ctaaatggct
     8401 ttcagaatta ttgtcttgtg atatttttga aactaagaat attaatatag aaaaggttat
     8461 gaagtatgat acgattattt taggaggagg tctttatgct tgtaatatag cgggaatttc
     8521 tttcttaaaa aaaaattata aagaattgca gaaaaaaaat ttagtagtat ttggcgtagg
     8581 agctgctcca tatgatgatg aagtaataaa gaaattaaga gaagtaaatt ttaaggatga
     8641 attaaacaaa attccttgct tttattgtcg tggggcatgg gatgagacaa aaatgtcttt
     8701 tatagattat actctttgta gtttttttaa aaaatctata gctaaaaaag aacgtcaagg
     8761 tcttaaacca gcagaagcac ctttattgtc tggagaagcc tttgattggt gtaataaaga
     8821 aaatttaact ccaatacttg attatataag agaactttaa gaggtatata tttgtaatta
     8881 tttattatct aaagttagat ttcatagaaa cttactagac attatttata aaataatatt
     8941 attaaagatg gataatttaa ttgtttcaat aaggttataa ttttaaaaaa tgtttatttt
     9001 aaaataaact attttataag cttacttata cttaataagg ggcttttttt attggaagat
     9061 ttatgttata ttgagatgaa tttattatga tataaaaaat aatgttagga taaatttaaa
     9121 tctttttcta aaaatgtatt agtataattc ttaaagaaag gatttttaac aatggatata
     9181 aaagagttag ttaaaatgca aagaaaatat tataatacag gtaaaacaag agatatatcg
     9241 tttcgtatag aacagttgaa gaaacttaag ttagttgtat cacaaaatga agaaaaaata
     9301 cttttagcac taaagaaaga tttaaataaa tcggattttg aaggttttat gacagaggta
     9361 ggcatgtttt atagtgaatt aaactttgct ataaagaata taagaaaatg gagcaaaata
     9421 aaaagagtta aatcaagtat ggttaatttt ccatctatat ccaaagttgt tccacaacct
     9481 tatggtgtta ctctcataat gtcaccttgg aattatccat ttcaattagc acttatacca
     9541 ttagtttggt cattagcagc agggaattgt gttatattaa aaccttctga atattctgtg
     9601 tcaacatcta gtgtagttaa agacatagtt gaagatactt tttcaaaaga atatgttgca
     9661 gttgttcaag gaagtcaaga agaaagtgaa aagttactat tggaaagatt tgattatata
     9721 ttttttacag gaagtactaa tgttggtaaa ataatcatga aatcagcatc agagcattta
     9781 actcctatta ctttagaact tggaggaaaa agtccttgta tcattttaaa agatgctaat
     9841 atagacctta ctgccaaaag acttacttgg ggaaaactaa taaatgcagg acaaacctgc
     9901 gtggctccag attatgtttt agtgcatgaa gatagaaaaa atgagttaat agagaaaata
     9961 aaatattata ctaataagta ttttggggat aatgcatgta ataatgagca atttcctaaa
    10021 atcataaatc agagacattt taatcggata ttatctctta ttgataaaga taagatagtc
    10081 tatggtggaa attataataa ggagacatta aagatagagc caactatagt agacaatgtt
    10141 aattgggatg ataatataat gaaggaagaa atatttgggc ctatatttcc cattttaaca
    10201 tataaagatt tagatgaagt aatacaaaaa attatacaaa tgccaaatcc attggcactt
    10261 tatattttta caaaaaataa gtacctagaa aataaacttt tagaaatgat tccagcaggc
    10321 ggatgttgta tcaatgatac agttactcat atagctacga attacttacc ttttggtggt
    10381 attggtgaaa gtggtatggg ctcatatcat ggaaaagctg gattcgatac atttactcac
    10441 tataagagtg tgttaaaaaa attaaatttg gatgtcccta ttagatatgc tccatacgat
    10501 aataaattaa ttaaggttct taaaaagata atgtaggtta tattgtagaa taataaatat
    10561 aaataaaatt gagtatttgt attctgaata tattttattt ttaatttggt atatttgtta
    10621 taaaagtggt gattttgtga taaaatttaa ttatatagaa ataaggagga aaaaatgaaa
    10681 attaattgga atacaaaata cacaacaata gcaatttata catttataat agctgctagt
    10741 agtattatat tttatctagt atcatcacaa attgatgtat tttctaataa tttagatgct
    10801 atatttacaa cattacaacc ttttataata ggatttgcta ttgcatatct tcttaatttt
    10861 attttaaagt tttatgaaga cagaattttt ataaaaagtg agaaattaaa aaaactaaaa
    10921 caaagttcaa aaagaggctt gggtctttta ttaacatatg caacagctac attgatactt
    10981 tacttattta tgcatttcgt attgccacaa gtaattgaga gtattgttgg actagcaaat
    11041 gatataccta tgtatgtaaa caatgcaact aagcttattg ataaattaat gactgattta
    11101 aatcttgatg agcaatactt taatttggca gttgataagt ggaatgaatt tgttacatat
    11161 attataaagt ttgtaacaga tttaatccca atattaggaa gtatgttaaa gaatgtagcc
    11221 tctagtatat ggaatattgt actaggatta attgtttcag tgtacttatt aattgataaa
    11281 gaaaaattct atggattaag caaaaaaata acttatgcag tatttacaga aaaacaagct
    11341 gccagaattt tagaattaac tcatagaagt aactatacat ttggaagatt tttaggtggc
    11401 aaaatattag attcattcat tataggtatt ctaacatttg taatacttac gttagttaaa
    11461 atgccatata cattattaat atcagttata attggtatta caaatattat ccctttcttt
    11521 ggacctttat ttggagctat accatctacg ctaatagtga tgtttgtatc tcctataaaa
    11581 gctttctggt tattgttgat tatattaata atacaacaga tagatggaaa tattatagga
    11641 cctaaaatac ttggagattc aattggtata tctgcatttt ggattttgtt ctccttattg
    11701 gttgcaggaa aattattagg ttttattgga atggttatag gagttccaat gtttgcagta
    11761 atttattcta taattaagga tattgttgaa agtaaattgg acaaaaaggg attaccgaca
    11821 gatacttccg attatatgta gctaaaaaat attatgtata attaaaaata tataaattaa
    11881 gcaatattta aagcactgag aaagttaaac tcttggtgct ttttagatat aaaattatta
    11941 tagaagaggt gttttttgtg gcatttatag aatgtaaatt taaatctaaa tatactggag
    12001 gagaaactga tataattgta attttgcctg tagcaaatgg aaaagaactt tttagtggta
    12061 aagagatata tgattttgaa ggtaaattta aaacattata cttatttcat ggtttagaag
    12121 atgaccaaag ctcatggatt agatatacta atgtagagca ttatgctaaa aataaaaata
    12181 tagccctagt aataccaaga gtagaaacta gtttttatac tgatatggcg tatggacacc
    12241 aatattttac ttttgtaagc gaggaattac ctaaatttgt tagagctata tttcctttat
    12301 cagataaaag ggaagataac tttgtagctg gtatgtctat ggggggatat ggagctttaa
    12361 aattagcgct ttcaaaacca aaagagtttt cggcagttgc aagtttttct ggttcgcctg
    12421 atatgattca tgagttagaa aatcaacaaa tagaaaccaa tgcagacatt ctatttcacg
    12481 attttggtag accagaagac gctagaaata gtgagaatga tttactttac atacttaaga
    12541 accttaaaga aagaaatgaa gatattccta aaatttatca attttgtggt gatagagatt
    12601 ttttatataa aaataatcag atgtttaaaa aatatgcaga ttctctgggt gtagatgttg
    12661 aatatgaaga gtgtgtaggg gggcatgaat ggcgtctttg gaatttatgg ataaagaaat
    12721 ttatagatat aattggatag tacacttatg gtattaacag gtatactata aaatatcttt
    12781 aaatatgata aagactgaaa tcctaaaatc aaattatgat tttaaaattt cagtctctaa
    12841 gaatttaata aaattttatt aagttcttac acgagttatt attggagtaa aattgtcaac
    12901 tatatctata tagtatttac tcaattcctc taaaatctct tcgcataaat ccgtactatg
    12961 accaagatta ataagaaact gttttgtaaa atgctttatt acagcttgag aagatatatc
    13021 gtacttgtgt gaagtataaa ctctaattat ttcaggtttc atagcaagta taccaataca
    13081 agaaagtatt aattcatcat gttctataga ttctttatca ttaacatatc ttttcatgac
    13141 catttcggtt acacttcttt gatagcttaa aatagcttct tcataagcta tatccaaata
    13201 aaaatttcta tatgcttcgt tttttagaag gaaacaaagg tcagcattca tagcaagaaa
    13261 gaacatcatc atagtacctt cttcatggta gttatagatt aaagactgca tttcatttct
    13321 tatatcttca tatattatag ctcctatttc gcttttactt gagaagtaat agcttattag
    13381 acctaaattt atattagctc tttctgcaat ttgcctagtt gttgtcttat gataaccttg
    13441 ctcaaaaaat aattctctag cagcacttat aatactagct tttgtttctt tgcccttttc
    13501 tgattttgac atatttactg tgtatacctc tcttttcaat ctttttttga aaatttgcta
    13561 actataaata ttgtaataga accacctatt ataggaacca aaattctgtc aaatacagta
    13621 agaataccaa tcatatttaa taatgccaat ataacactta ctataacagc atagatagct
    13681 cctttttttg tagcaccttt ccagcaaaga ccaattacaa atggtgcaaa tattacacct
    13741 gtacataatg gagctggcca aaacaataat tctaataaac tatcaaattt aagtgctatg
    13801 attgcaccta ttatagctgt caaagctgat gcaatttgag aatactttag agtatttttt
    13861 aaatcattaa attctatatt aggatgtaat aatttgttat aaatatctct tgatataata
    13921 gcactcattg aggtcattaa tgaatcggca gtagacatta tggcagccaa tatagcagct
    13981 aagaataata cagatattaa aggtggcaaa gtagtcgata tcatttgagg taaaacctga
    14041 acagatgata tatttggaaa taaactacca ccaatagctc caattattcc tatagggaaa
    14101 gcaagaaata atagtataaa tcctgcaatt acactacttt taactgcatt tttagcatta
    14161 tcagcacatt gatatcttaa aaaactttca taagaaaata ttgagcctaa aactaatggt
    14221 aaaactgtat acataaaatc actaatcgat ttatttcctg gaaagaatgg ttcttttacc
    14281 attgattgta acataagtaa agggttgtcg ccaactaatt ttaagcttat ataagctact
    14341 attggcaaaa acactataca aatagcaagt tgaataaatg ctgatactgc aactccccac
    14401 attcctgatg tataagtata tataatgata actataactc ctataattac agctatatca
    14461 taaggaatac caaatgcagt agatacagaa ccaaaagaaa tcaattgact acccataata
    14521 gctagtatag atattggtgt tacaagactt tgataagctc ttaaaaatac actatgacca
    14581 tatctagttt caatataatc agcaggtgtt atatcacaag ataagcttct taattttcct
    14641 gcgaaaaatg catttataaa gcaagctaaa gctgcaccta tagtagaata cattccaacc
    14701 caaagtcctc tttcagctcc ccattgaact ccaccaacta agcaccctcc tccaaaagat
    14761 gtagcagcaa tggttgcagc tagtataggc aaaggcagat ttctacctgc gattaggaaa
    14821 tcggatgctg ttttaacttt ttttgaaaaa taaaaaccaa tccatatgta tattgcacac
    14881 gtaacaatta aaagtaacat agtcttttct cctttataaa atattttaat aaaatataca
    14941 aaatatattt a
//
LOCUS       DAEHWO010000099        14414 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEHWO010000099 DAEHWO010000000
VERSION     DAEHWO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14414
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.101"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..995
                     /locus_tag="KNP54_003438"
     CDS             <1..995
                     /locus_tag="KNP54_003438"
                     /inference="COORDINATES: protein
                     motif:HMM:NF025159.1,HMM:NF037393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4179 domain-containing protein"
                     /protein_id="HBF0894298.1"
                     /translation="KKKMNRRKSITVTLISFFILGLIALNSETTWAYIRDTTKQIESF
                     FGREKNIFDKYKFEGEQIIESNGLKFSLGEVILDDRQLIVSMSADYTDFKIKFKNIGK
                     VGISPSFPTIYIDDLVFPGQSYSTITEKVKGEKKYNILLKVSLLQIDTNKDGIADTEY
                     EILNKINSNKNYSLKISFTDIDYGIKNGIENNVGNWKFNTTINASNIIKDTKVYEVDK
                     EIKIDEKEYKGTLNIKEVRVSPISIKVKYNYDSYTEIGPAKRSDPYLIIKDENGKKLN
                     NGTGAGGILQNKKNYINGEFELRGSEKKITIIPCIYVNDKEKCLFNKTVNLNID"
     gene            complement(1050..1643)
                     /locus_tag="KNP54_003439"
     CDS             complement(1050..1643)
                     /locus_tag="KNP54_003439"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894299.1"
                     /translation="MNKDKFNELDISEQIEYINNQLENNETLTYICKNIGIGRSTVRD
                     RFKKANYSYSKDLNKYIHECITDVLQEPSIKNNRCITTDIQKEKNNISNTNITQSDAV
                     REVINKSDKEIKDNLLDIVSNYDVLKEIIELHKCNTSVIKQQIVIDLEDSDSKLTTLR
                     VNSKELELFNRFCDDNKYFKKIDLISQALKEFREKYS"
     gene            2659..2940
                     /locus_tag="KNP54_003440"
     CDS             2659..2940
                     /locus_tag="KNP54_003440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin VbhA family protein"
                     /protein_id="HBF0894300.1"
                     /translation="MKDYSIKNTTKEQRKEIVNSALGLGSIDSHEPSIVVLELLDRYV
                     EGELEIKEIQDIVLNSYKRKYLDGDEEGIEKMMDEIIDQNIDALKKLSE"
     gene            2955..3179
                     /locus_tag="KNP54_003441"
     CDS             2955..3179
                     /locus_tag="KNP54_003441"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894301.1"
                     /translation="MYIVAKKIDKVGCIASEVESGERIGALIEYLSLTMLDKGIEIVV
                     LDKPNMYGEYAPYEFLSEVEFVCSVLSMSH"
     gene            complement(3399..3665)
                     /locus_tag="KNP54_003442"
     CDS             complement(3399..3665)
                     /locus_tag="KNP54_003442"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894302.1"
                     /translation="MDDKRNPLLKQLIVIEEFYGEEKITDIKKFIEFLKNNNLEFINL
                     QGCSIEINLKKEMISIIQNITNERVLEFTYEYLKQIDNKTKTYI"
     gene            3877..4068
                     /locus_tag="KNP54_003443"
     CDS             3877..4068
                     /locus_tag="KNP54_003443"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894303.1"
                     /translation="MLFSNREKRDKYIQIRLTETEKQNLKDIIDRLNEDSSKKISLTD
                     FILNAIDYYIEHECKNYKK"
     gene            4088..5128
                     /locus_tag="KNP54_003444"
     CDS             4088..5128
                     /locus_tag="KNP54_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBF0894304.1"
                     /translation="MKGIKKLTSLGLVGLLFSMSVFHSNAFTLERIQGKNKYETAGLV
                     ADKQQYTTAILINADSTMSDGLSASGLAGVNNAPILLTQKNNIPKETLERVERAKKVY
                     IIGGENSIDKSTEGILKDKGKEIKRLQGDDRIKTSYSVAKEINAIKKVNTIMLTNAFK
                     GEVDTMSIAPIAIMKNAPIILTNGSTIPFKFDKTITSYVVGGNKSMTDDLLIKTNSQR
                     LTGVDRYATNRNIIKSFYNRAVEEFYIASGTDLVYPLIASTIVKDKPMVLVNESNNKE
                     ILRNASKITVVGDLDESIIKKCLDVKDGKSETKTKKEKIYVEGFGWVEPTDSEGEEGN
                     SDGDFNKIVANM"
     gene            5495..6073
                     /locus_tag="KNP54_003445"
     CDS             5495..6073
                     /locus_tag="KNP54_003445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894305.1"
                     /translation="MKFKEIKKKNYVIGGVLLIMISVSIFIFKDSSNKGESLTNQVKN
                     ETGHKIKEEVKNVDVPKINMDEGSSESKMKMAEKINKENNITQEDYRNFREGIEKKEN
                     EPIKKPNKPNKPNKPNSNIINPEVKPSNNENSVKNNNPEENKNNESENKSEENKKEKV
                     YVEGFGWVEPSESQGKEGTSNGDFNKVVGQMD"
     gene            6093..7868
                     /locus_tag="KNP54_003446"
     CDS             6093..7868
                     /locus_tag="KNP54_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008423834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894306.1"
                     /translation="MKKRLLIVFLCVTLFIPILVFADGSGNVDGGGGSTGSGGDKKNY
                     WTAGDEGVRITIIDNKTQKPVSTPIDFTNRNINVKVHFGKVSKISYREGKTLNLDSGK
                     YNYINPKNKLPVIISSKTYGKSDIKKIKEYFCNDWTQRIIAKEANFNYEEMQNGEYKL
                     LLEPVAYFTFNGNKMAMTATEAALYNKKLGGNKLRNKFASISHKNLPLAMFLEKDDLG
                     FKAWKGISDTDKAKAKDDDTIIKMLGLGIVYFNNEPTKDDEVTIPPVEPSTPENPDKP
                     SIDGKEYEYHTDTDVISSVKIKGSNRSPDNPVTVKFKIKNQTYNMNNIYLPEEGGEQY
                     AWVKWHTPKTPEKIIIEVSSNATTDKAKIIADVVELEEKTPPDPVAKDKRPNNFKVPT
                     LPKKEETKTLEWGKWDCNWKAVWVYYSDGEGGGEWVDEGYWVWKWIPYSATINATMDT
                     IPSEHCMTQKKTRDVYEMKSAYGIETLVNSKITFNAPEDSVTGGQNVIVTFPEFGYEK
                     YNRVLQNTKIGYDSSFEFKKNKYSTYNAKTHFTPLWYLDGKYSTYATVIDSWTPAGQL
                     KTNIYNDKITIKGNVYDDWHIGPVK"
     gene            7890..9299
                     /locus_tag="KNP54_003447"
     CDS             7890..9299
                     /locus_tag="KNP54_003447"
                     /inference="COORDINATES: protein motif:HMM:NF013258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBF0894307.1"
                     /translation="MAFFVYHLAKYSKNNIVGIQKHNQRQNKSYKNKDIDMSKSKLNI
                     DFENKDRIKYLEKVEKIIKENRTKGKVIRKDAILMCESVISASPEFFLGMEQSEKEKY
                     FKYSYEFLKDRYGEKNVISATVHFDETTPHMHFSFVPITSDGKLSARDLITRIELKKI
                     QDELPIYLQSKGFDIKRGREHSEARHMQPEDYKKQQIQELRELENKLEYVKKLFKGFE
                     KPLNSFNELEPANIKKNLITGKETVYKNDYDEVIDILKGTMKENLELKEKLHNEQLKT
                     RNLEVKLNTVNEYERLTHEKEKKLKLEKEEFEEQKQLISEREKNIEKVLENKDKNNKK
                     ILDEKEVEINELEKQYKNLSRKYNNTIREYEKVIEEFSNNDIYIIFNKSSTKEIQEND
                     TYKFKDANNFIKELNKMCFTNNETREIGFQMSFGINNGVFMEKNIILGQYRDMDLKRE
                     IISINKSNNKVLSKDLFRY"
     gene            complement(10086..10730)
                     /locus_tag="KNP54_003448"
     CDS             complement(10086..10730)
                     /locus_tag="KNP54_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBF0894308.1"
                     /translation="MIIVYERVSTRKQDNSRQERVLENEGIKFDKIYRDKITGATKER
                     KALNRMLLEVNEGDVVYCESISRLGRNLKDLIDIIDTLVQKGVMVKILKEGIDTGNNT
                     YKLLLGIFGAVAEMERETIQERTQQKIDQLKEDKKKGEINTKTGKWFGRQKVTKELLE
                     TNKEFIKYYNKILDGNLKKNEVAKILNIGRTTLYEWIKIFEGGEIKRSNRSDKN"
     gene            complement(10936..11373)
                     /locus_tag="KNP54_003449"
     CDS             complement(10936..11373)
                     /locus_tag="KNP54_003449"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894309.1"
                     /translation="MKLKLKKSFIFITTLSFIFTNLSISLPVFADSLQENIMTIQEPR
                     YTNISKATSELSISGSNAIIKTTLLGKLGITKTTITSTLQKKVNNNWQTVDSWTVSKN
                     DKLCTLSKTKSISKGTYRVSSVVIAYKGSTSERDTLISASKTY"
     gene            complement(11436..12137)
                     /locus_tag="KNP54_003450"
     CDS             complement(11436..12137)
                     /locus_tag="KNP54_003450"
                     /inference="COORDINATES: protein motif:HMM:NF025643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HBF0894310.1"
                     /translation="MNDFKITDEELRKALENVELILISKVPKEDDIDYTFSKSFENKM
                     EKLIKQETKKTLRKNTYSYSKNIVAALLIIIIGLFAMTMSVDAMREQFFNVIKEVYTK
                     FTTYKFSINENIDIGKFNELNLSYLPKGFKEINKTNISNETFVFFSNDDGDEIVFNYS
                     KIADTTMKIDTEEAIIENVKINGINAEYIIKNNDFSLIWNDNTYSYYITLSYIEYIKL
                     QDTKNEIIKIAENIK"
     gene            complement(12140..12670)
                     /locus_tag="KNP54_003451"
     CDS             complement(12140..12670)
                     /locus_tag="KNP54_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBF0894311.1"
                     /translation="MILYLNLLESENDISKFELLYNTYKKTMFYIANEILKDECLAED
                     AVHESFLKIIKNLNKINDIKSYKTKAFVIIIVKNTSKDIYRKRKRENEKIKSLEKEFQ
                     SDKFHIDEYSIGYLEEAIMKLSEKHRDVLLLKLQHELNDKEISQILDIKPENVRKRLS
                     RAREELKYIFIKDVGV"
     gene            12810..13577
                     /locus_tag="KNP54_003452"
     CDS             12810..13577
                     /locus_tag="KNP54_003452"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894312.1"
                     /translation="MFLKKLKKSTVIALTGLMLISSTGNLAFALDNKNEGAKNVSENS
                     IVEPRVVSNSKTFSVGGKSYTNYTSANITLSSGAYGSTTIKSNSGAVGENRLYAHANL
                     YNKNGQVVKTADWKSNGSSTSTLTNTTGNSFSKGTFYTKGTTKVYNGNGYTTQSANQS
                     PNVVVNNLGTRISKEELKERMDLYEIKNMLPAVGIDNISGYISMDDLYDEPNFPETPE
                     EAITYQKIRAKASYRMIPLYDNDGKTIIGEYRIDSAN"
     gene            13774..14352
                     /locus_tag="KNP54_003453"
     CDS             13774..14352
                     /locus_tag="KNP54_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0894313.1"
                     /translation="MRKLSSFKNLINQNQNDNDNMVISAINGNKHAIEQLINEQKEYL
                     YKTAFLYTKDENEAMDICQETIYKTILNIHKLREPSCFKTWMTKILINNVNEVNRNKI
                     KIFDNDFQIELIKDISYEKLEEKLDLYSAIDLLEEKFKTPIIFQYFQDMTIKEIAEVL
                     ECNENTVKTYLRRGKKKLYEILMRGEIDEKVR"
BASE COUNT         5727 a         1670 c         2098 g         4919 t
ORIGIN      
        1 aaaaaaaaaa aatgaataga agaaaaagca taacagtaac attaataagc ttttttattt
       61 taggattaat agctttaaat agtgaaacaa cctgggcata tataagagat actactaaac
      121 aaattgaatc tttttttggg agagaaaaaa atatttttga taaatataaa tttgaaggtg
      181 aacaaattat tgagagtaat ggattaaaat ttagtttagg tgaagtaatt ttagatgata
      241 gacaattaat agttagtatg agtgctgatt atacagattt taaaatcaag tttaaaaata
      301 taggtaaagt aggcatttct ccttcattcc caactattta tatagatgac ttagtatttc
      361 caggacagag ttattcaaca ataacagaaa aggtaaaagg agaaaagaaa tataatatac
      421 tattaaaagt tagtttattg caaatagata ctaataaaga tggaatagca gatactgaat
      481 atgaaatttt aaataaaatc aattctaata aaaattatag tttgaaaatt tcttttacag
      541 atattgacta tggtataaaa aatggaattg agaataatgt aggtaattgg aaatttaata
      601 ctacaattaa tgcatcaaat ataattaaag atactaaagt atatgaagta gataaagaaa
      661 ttaagataga tgaaaaagaa tacaaaggga cattgaatat aaaagaagtt agagtatctc
      721 caatatcaat taaagttaaa tataattatg atagttatac agaaattggt cccgctaaaa
      781 gaagtgatcc atatttaatt ataaaggacg aaaatggaaa aaaactaaat aatggcactg
      841 gagcaggagg aattcttcag aataagaaaa attatataaa tggggaattc gaactaagag
      901 gaagtgagaa aaaaataact ataatacctt gtatatatgt taatgataaa gaaaaatgcc
      961 tttttaataa gactgttaat ttaaatatag attaaatcaa aataaaacca taggttatta
     1021 acctatggtt ttattttgat ttaataattc taagaatact tctctctaaa ctcttttaag
     1081 gcctgactaa ttagatcaat ttttttaaaa tatttattat catcacaaaa tctattaaat
     1141 aactctaatt ctttactatt aactcttaga gtagtaagtt tactgtcaga atcctctaaa
     1201 tctattacta tctgttgctt tataacggac gtattacatt tgtgtaactc tataatttct
     1261 tttaatacat cataattaga aactatatct aacaaattat cttttatctc tttgtcagat
     1321 ttattaatta cttctcttac tgcatccgat tgtgtaatat ttgtattact aatgttattt
     1381 ttttcttttt gtatatcagt cgtaatacat ctgttatttt ttatgcttgg ctcttgtaat
     1441 acatctgtta tacattcatg tatatacttg tttaagtctt tggaataact gtaattagcc
     1501 tttttaaatc tatcccttac tgtacttctg cctattccta tatttttaca tatgtatgtc
     1561 aaggtttcat tattctctaa ttgattattt atatattcta tttgttctga tatatctaat
     1621 tcattaaatt tatccttgtt catattacac ccccacaatt ataacagatg tataacgtct
     1681 gttatttgaa attatatcat aatattattt taaataaatt tggagtttta aaatataatt
     1741 agcaaaaatt acaaaaaata tgttgttata tcctcagaaa gaatttatac ttaaatatat
     1801 aaaaactaaa taaaaaagca cttacaaaaa gtaagtgctg tctgtaactt cagttcttta
     1861 aatcgcctag gaaacgattt aaggtaacaa ctggtataca aagtaccaag aagttaagga
     1921 ataatccaat cgcaagatag gctaaatcta tcaaggagag ttgacccaac tgaaattatt
     1981 tacaaaatat aattatagta tataaagtaa aataatttta gtcaaggaga aatgttgtac
     2041 acctaaagta tagatataga ctttaggtgt tttttaatgc aataaatgag gttatatgtt
     2101 acctatatga catatagtgg gacagccctt aaccacttaa aaaaaaggtc aggtgagttc
     2161 agccaatgca taaagtgaac ctctgtacaa tgtagctaat ccctttttgt agctagtaca
     2221 ggattgagtg gtgacgacaa cctaaaggtc gggtgtggga gttctaggag cataagtgct
     2281 tgggaactat gaacagaatc attgcattag gatagaacca taatgtagaa agtttatagg
     2341 tgtttacacg taataaaaag ggtacagatg ataaggtgac cgaagtatac ggtttataga
     2401 tttgtaatta cttccttatg atagtcaatt taaaagtaat gactattata agggaataat
     2461 tacgtccaat ttcagttccc tcgtgccggt ttattatttt agtgaacttg tcaagataaa
     2521 atttaaatag ggataacaaa attcgatata ggacaagccc ctctggcttg gcatatggag
     2581 aatgcgttag taaccactta aagcctaagg ttaaagtggt tactaaccgt taggttcaat
     2641 aaaaggaagg tgaaaattat gaaagattat tcaattaaaa atacaactaa ggaacaaaga
     2701 aaagagattg ttaattctgc acttggatta ggctcaattg attctcatga acctagtata
     2761 gttgttttag aattgttaga tagatatgtt gaaggagaat tggagataaa agaaattcaa
     2821 gatatagtgc ttaattctta taagagaaag tatcttgatg gtgatgaaga aggtattgaa
     2881 aaaatgatgg atgaaataat agaccaaaat atagatgctt taaaaaaatt atctgaatga
     2941 tatgaggtga actaatgtac attgttgcaa aaaaaattga caaagtaggt tgcattgcat
     3001 cagaggtaga aagtggagaa aggataggtg cattgattga atacttatca ttaacaatgc
     3061 ttgataaggg gattgaaatt gttgttttag ataagccaaa tatgtatgga gaatatgctc
     3121 catatgagtt tttgagcgag gttgagtttg tatgtagtgt tttatcaatg agccattagt
     3181 ggtctaaata gaccactagg gcgttccaaa agtgaccact tttggtatat aggtttttaa
     3241 tgcctcgcag agcttaccac tttgccaaca tagtgcaaag tatagtaagt tagacttata
     3301 tatataaata tgttgtttta aattacattg gtaatttaaa acttccagaa catggacagt
     3361 acatttgtaa gtacatccat gttctggaag tcatattttt atatataagt cttggttttg
     3421 ttatctattt gtttcagata ttcgtatgta aattctaata ccctttcatt agtaatgttt
     3481 tgaattatag aaatcatttc tttttttaag ttaatttcta ttgagcagcc ttgtaaatta
     3541 ataaattcta agttgttgtt ttttaaaaat tctatgaatt ttttaatgtc tgtgattttt
     3601 tcttcaccat aaaattcttc aatcacaatt aattgtttaa gtagtggatt tcttttatca
     3661 tccatattat cctccttttt gactataact caaaaaagat atatactgta cttgcgatgt
     3721 atagtgctat atgctccttt ggggctatag tgcttttttt attataataa caatgcaaat
     3781 acgatttgtc aatacagaaa gtaattattg aatgtattga catgaacggt attctgtgtt
     3841 attttataaa tataaaatta taaaaggaga aattaaatgt tattttcgaa tagagaaaaa
     3901 agagataaat atatacaaat acgtcttaca gaaacagaaa aacagaattt aaaagacata
     3961 attgatagat tgaatgaaga tagttctaaa aaaataagtt tgacagattt tatattaaat
     4021 gctattgatt actacataga gcatgaatgt aaaaattata aaaagtaaaa aagagggggt
     4081 attttttatg aagggtatta aaaaattaac atcattaggt ttagtcggat tattattttc
     4141 aatgagtgta tttcactcaa atgcttttac tcttgaaaga attcaaggaa aaaataaata
     4201 tgaaactgct ggtcttgttg cagataagca acaatatact actgctatat taattaatgc
     4261 agatagtaca atgtcagatg gtctttcagc aagtggactt gcaggggtta ataatgcacc
     4321 aattttatta acacaaaaaa ataatatacc aaaagaaact cttgaaaggg tagaaagagc
     4381 caaaaaagta tatataattg gtggagaaaa ttctatagat aaatcaacag aaggtatttt
     4441 gaaagataag ggaaaagaaa ttaaaagact tcaaggtgat gatagaataa aaacaagcta
     4501 tagtgttgcc aaagaaatta atgcaataaa aaaagttaat acgataatgc tgactaatgc
     4561 ttttaagggc gaagtagata caatgagcat agcaccaatt gcaataatga aaaatgcacc
     4621 aattatactt acaaatggaa gtacgatacc atttaaattt gataaaacta ttacaagtta
     4681 tgttgttgga gggaataaaa gtatgactga tgatttactt ataaagacta attcacaaag
     4741 actaactgga gttgataggt atgcaactaa tagaaacata ataaaatcat tttataatag
     4801 agcagtagaa gaattttata ttgcaagtgg aacagattta gtatatcctc ttattgcttc
     4861 aactatagtt aaagataaac caatggtttt agttaatgaa agtaataata aagaaatatt
     4921 aagaaatgca tctaaaatta ctgtagtagg agatttagat gaatctataa taaaaaaatg
     4981 tttagatgtt aaagatggaa agtcagaaac caaaactaaa aaagaaaaaa tctatgtaga
     5041 aggatttgga tgggttgagc caacagactc agaaggagaa gaaggtaact ctgatggaga
     5101 ttttaataaa attgtagcta atatgtagtt gtatactata cattaaaaga atataatagt
     5161 attaagagat ttattaggtg tcccaaaatg taataaatgt aataaaaacc aaataactct
     5221 atatttatgt tcattttgga atgtttgtta aatgtcccaa aatgtccgga atgtccgaaa
     5281 tgtccgaaat gtaataaaat tcaaataact ctatatttgt gttcatttta aggtatttgt
     5341 tgaatgtctg aaatgtctta aaaatgaaaa aacactaaag gtttgtaaat ttttagaaca
     5401 aatattttta taaaataaat aagtttaaat taagagagca gataatatct gctctctttt
     5461 ttaatacaaa aaattattta ggaggtaaaa atctatgaaa tttaaagaaa ttaaaaagaa
     5521 aaattatgtt attggaggtg ttctattaat tatgatttca gtttcaattt ttatttttaa
     5581 agattcttcg aataaaggag aatccttaac taatcaagtg aaaaatgaga caggtcataa
     5641 gataaaagaa gaagtaaaaa atgttgatgt tccaaaaatt aatatggatg aaggaagtag
     5701 tgaatcaaaa atgaaaatgg cagaaaaaat taataaagaa aataatataa cacaggaaga
     5761 ttacagaaat tttagagaag gtatagaaaa aaaagaaaat gaacctataa aaaaacccaa
     5821 taaacctaat aaacctaata aacctaactc taatattatt aacccagagg taaaaccaag
     5881 taataatgaa aattctgtta aaaataacaa tccagaagaa aataaaaata atgagagtga
     5941 aaataaatca gaagagaata aaaaagaaaa ggtctatgta gaaggatttg gatgggtaga
     6001 accatctgaa tcacaaggca aagaaggtac ttctaatgga gattttaata aagttgtagg
     6061 tcaaatggat taagaaagag agggtaagga ttatgaaaaa aagattatta attgtatttc
     6121 tttgtgtaac tttatttatc ccaatacttg tttttgcaga tggtagtggt aatgtagatg
     6181 gaggtggtgg aagcacaggg agtggtggag ataagaaaaa ttattggaca gctggtgatg
     6241 aaggcgtaag aattacaata attgataata aaactcaaaa acctgtgtca actccaatag
     6301 attttacaaa taggaatata aatgtaaaag tacattttgg aaaagtatct aaaatatcat
     6361 atagagaagg gaaaacatta aatcttgatt caggtaaata taattatatt aatcctaaaa
     6421 ataaattgcc tgtcataatt tctagtaaaa cttatggaaa atctgatata aaaaagatta
     6481 aagaatattt ttgtaatgat tggacacaga gaatcatagc aaaagaagca aattttaatt
     6541 atgaagaaat gcaaaatggc gagtataaat tattattaga gcctgttgca tatttcactt
     6601 ttaatggtaa caaaatggct atgactgcaa cagaagcagc gttatacaat aaaaagttag
     6661 gtggaaataa attaagaaat aaatttgcaa gtatttctca taaaaaccta cctttagcaa
     6721 tgtttttaga aaaagatgat ttaggtttca aggcttggaa aggtatctct gatacagata
     6781 aggcaaaggc aaaagatgat gatactataa taaagatgct agggttaggt attgtatatt
     6841 ttaataatga gcctacaaaa gatgatgaag ttacaatacc accagtagaa ccatcaacac
     6901 cagaaaaccc agataaacct tctatagatg gcaaagaata cgaatatcat acggatacag
     6961 atgttatatc ttctgtgaaa ataaaaggct ctaatcgctc tccagataac cctgtaacag
     7021 ttaaatttaa aataaaaaac caaacttaca atatgaataa tatatatttg ccagaggaag
     7081 gtggagaaca atatgcatgg gttaagtggc acacacctaa gacaccagaa aaaataatta
     7141 tagaagtaag ttcaaatgca accactgata aagcaaaaat tatagctgat gttgttgagt
     7201 tagaagaaaa aacccctcct gatccagttg caaaagataa aagaccaaat aattttaagg
     7261 taccaacttt gccaaagaaa gaagaaacta aaacattaga atggggtaaa tgggattgta
     7321 actggaaagc agtttgggtg tattatagtg atggagaagg tggtggagaa tgggtagacg
     7381 aaggttattg ggtttggaag tggataccat atagtgcaac tataaatgca actatggata
     7441 caatcccaag tgagcattgc atgacacaga aaaaaacaag agatgtatat gagatgaaat
     7501 cggcttatgg aatagaaact ttggtgaata gtaaaatcac ttttaatgct ccagaagata
     7561 gtgtaacagg ggggcaaaat gttattgtta cttttccaga gtttggctat gaaaaatata
     7621 atagagtttt acaaaacaca aagataggtt atgattctag ttttgagttt aagaaaaaca
     7681 aatattctac atataatgca aaaactcatt ttacaccact ttggtattta gatggcaaat
     7741 actctacata tgccaccgta atagattctt ggacacctgc aggtcaatta aaaacaaata
     7801 tttacaatga taaaattact ataaaaggga atgtatatga tgattggcat ataggtcctg
     7861 taaaataagt tgaagaaagg atttttttta tggcattttt cgtttatcat ttggcaaagt
     7921 atagtaaaaa taatattgtt ggtattcaaa aacataatca aagacaaaat aaatcttata
     7981 aaaacaaaga tattgatatg tcaaaaagta aactaaatat agactttgaa aataaagata
     8041 gaataaaata tttagaaaaa gtagaaaaaa ttataaaaga gaataggaca aaaggaaaag
     8101 ttataagaaa agacgcaatt ttgatgtgtg aaagtgtgat ttcagcaagt ccagaatttt
     8161 tcctaggtat ggagcaatca gaaaaggaaa aatattttaa atactcatat gaatttttaa
     8221 aagatagata tggtgaaaaa aatgtaattt ctgctacagt acactttgat gaaacaacac
     8281 cacacatgca ttttagtttt gttccaataa catcagatgg gaaactaagt gctagagatt
     8341 taataacaag aattgaatta aaaaaaatac aggatgaatt accaatatac ttacaatcaa
     8401 aggggtttga cataaaaaga ggacgtgagc atagcgaagc aaggcacatg caaccagaag
     8461 attataaaaa acaacaaatt caagaactta gggaattaga aaataaatta gaatatgtaa
     8521 aaaaactatt taaaggcttt gagaagcctt taaatagttt taatgaacta gaacctgcaa
     8581 atatcaaaaa aaaccttata acaggcaaag aaacggtata taagaatgat tatgacgagg
     8641 taatagatat actaaaggga acaatgaaag aaaatctaga acttaaagaa aaattacata
     8701 atgagcagtt gaaaacaaga aatttagaag ttaagttaaa tacagtaaat gaatatgaaa
     8761 gattgactca tgaaaaagaa aaaaaattaa aattggaaaa agaagaattt gaagaacaaa
     8821 aacaactaat atctgaacgt gaaaaaaata ttgagaaagt actagaaaat aaagataaaa
     8881 ataataaaaa gattcttgat gaaaaggaag tagaaataaa tgagctagaa aaacaatata
     8941 aaaatttatc aagaaaatac aataacacaa taagagaata tgaaaaagtg attgaagaat
     9001 ttagtaataa tgatatatat attattttta ataagtctag taccaaagag atacaagaaa
     9061 atgacacata taagtttaaa gatgccaata atttcattaa agaattaaat aaaatgtgtt
     9121 tcactaataa tgaaacaaga gaaatagggt ttcaaatgtc atttggaatt aataatggtg
     9181 tttttatgga aaaaaatatt attcttggac aatatagaga tatggatttg aaacgtgaga
     9241 ttattagtat aaacaaatct aataataaag tactttctaa agatttattt agatattagt
     9301 aataatttag gcttagaata tataattatg caacttctaa gcctagcgaa atttaactcc
     9361 ttaaactatt tcgttgttta taaagaatta gcccaactgt aagaatagcc aataataata
     9421 tggtttttat aatttcagca tatatcgtag tgttgaatgc tataccatta atagtaaaca
     9481 tatactttct attaatcatt gtatagatac atatgagtaa aaataaaata tttttttatg
     9541 ctttgaaaga aagtattttc ttaaaaaaaa tatttcaagt attataaata ataaaaataa
     9601 acctatatcg tttacaccta ttttaattcc cacaatatca cttccccccc gtaatatatt
     9661 tatacttact ttagagttta tcaaatattt ctgaaaattt atatatacat attttcaaat
     9721 taaactagtt ctaaaattga cgtttagaaa ccatgagatg agatgtagca attctaatat
     9781 tttaataatt tatattttat aactattttt ttagttatgc taaacgaagg cgttaaacta
     9841 aatttattta aggtatattg ataacaactt ttttcttctg tagtattaca taaaaaaata
     9901 ttataattta ttatttttat tagttctttg ttatgaaata aatagcttat taaacaaaat
     9961 ctaaaatcac ttatattgac taatcatctt tgtttatttt tatacattaa tctggtcacc
    10021 caaaaaataa aattaaatat tctaagccat catcattcta aaataaaaaa gaactagcta
    10081 taactctagt tcttatctga cctattactt cttttaattt ctccaccctc gaatattttt
    10141 atccactcat acaatgtagt tctgccaata tttaatatct ttgccacttc attcttcttt
    10201 aagtttccat caaggatttt attgtaatat tttataaatt ctttgttagt ttctaaaagt
    10261 tccttagtta ctttttgtct accaaaccat ttgcctgttt ttgtatttat ctcccctttt
    10321 ttcttatcct cttttaactg gtctattttc tgttgagttc tctcttgtat tgtttctctt
    10381 tccatttctg caactgcccc aaatatacca agtaataact tataagtatt gtttcctgtg
    10441 tctatacctt cttttaatat ttttaccatt acaccttttt gaactaatgt atctataata
    10501 tcaattaagt ccttcaagtt cctacctaga cgacttatag actcacagta aacaacatct
    10561 ccctcattta cttctaataa cattctattt aatgcttttc tttcttttgt agctcctgta
    10621 attttatccc tatatatttt atcaaactta attccctcgt tttctaaaac tctttcttgc
    10681 ctactattat cctgttttct tgtgcttact ctttcatata ctattatcat aactataccc
    10741 ccgtttattt tgttataata attatacaat atattttttg tccgtttaaa ctatattttt
    10801 tgcattttaa ataccgaaca tatcttgata cttattgcca acacttttag tttaaatcta
    10861 tataaaatat tacagtacgg ttaaacgttg gtttattcaa acataattat gcaataatat
    10921 gactatttat ataatttaat atgtttttga agcacttatt aacgtatctc tttcagatgt
    10981 agatccctta tatgctataa ctacagatga aacacgatat gttcctttac ttatagattt
    11041 tgttttactt aacgtacaaa gtttatcatt ttttgaaacc gtccaactat caacagtttg
    11101 ccagttatta ttaacttttt tctgaagtgt agatgttata gttgtttttg taattccaag
    11161 ctttcctaga agtgtagttt ttataatcgc attacttcca gatatactaa gctcactagt
    11221 agctttactt atattagtat atctgggctc ttgaattgtc ataatatttt cttgtaaact
    11281 atctgcaaaa actggtaaag atatagataa attagtgaaa ataaatgata atgttgttat
    11341 aaatataaaa ctttttttta attttaattt catagaaatt acctcctaat aatatttata
    11401 tatataacga tataaaaagt aattttgtga catttttatt ttatattttc tgctattttt
    11461 attatttcat ttttagtatc ttgtaattta atgtattcaa tataactcaa tgtaatataa
    11521 tatgaatatg tattatcatt ccatattaaa gaaaagtcat tattttttat gatatattct
    11581 gcatttattc cattaatctt tacattttcg ataatagctt cttctgtatc tattttcata
    11641 gttgtgtcag caattttaga gtaattaaaa actatttcat ctccatcgtc attactaaaa
    11701 aatacgaatg tctcatttga aatattagtt ttgttaattt ctttaaaacc ttttggtaaa
    11761 tatgaaagat ttaattcatt aaattttcca atatcaatat tttcattaat tgagaatttg
    11821 tatgtggtaa actttgtata tacttctttt attacattga aaaattgttc tctcatagca
    11881 tcaacactca ttgtcattgc aaataaacca attataatta ttaataatgc agctactata
    11941 ttttttgaat agctataggt attttttctt aaagtttttt ttgtttcttg ttttattaat
    12001 ttttccattt tattttcaaa actttttgaa aaagtatagt ctatatcatc ttcttttgga
    12061 actttactaa ttagaatcaa ttcaacattt tcaagtgctt tacgaagttc ttcatctgtt
    12121 attttaaaat cattcaatat taaacaccca catccttaat aaaaatatat tttagctctt
    12181 ctctagctct agatagtctt tttctaacat tttcaggttt tatatctaat atttgactaa
    12241 tttctttatc atttaattca tgttgtaatt ttaagagcaa tacatctcta tgcttttcag
    12301 aaagcttcat tatagcttct tctaaataac ctattgaata ttcatcaatg tgaaatttat
    12361 cagattgaaa ttctttttca agggatttta ttttttcatt ttctcttttt cgttttcgat
    12421 agatatcttt ggaagtattt tttactatta tgataacaaa agctttggtt ttataacttt
    12481 tgatatcgtt tattttattc aaatttttaa ttatctttaa aaaactttca tgaacagcat
    12541 cttctgccaa acattcatct tttaaaattt cattcgctat ataaaacata gtttttttat
    12601 atgtattata taataattca aatttggaga tatcattttc agattctaat aaatttaaat
    12661 ataatatcat gtataaattt tccccttaat catatatata ttttccttat acattatact
    12721 cttttaaata aaaaatttaa aaaaattgtc acaagattaa tttatataac gttttatatt
    12781 atgaaaacaa taataaaggg ggaaaaacta tgtttttaaa aaaattaaaa aaatctacag
    12841 ttattgcttt aacaggacta atgctaataa gttcaacagg aaatctggct tttgcattag
    12901 ataataaaaa tgaaggggct aaaaatgtat ctgaaaattc aatagtagaa ccaagggttg
    12961 ttagtaattc aaaaactttt tctgttggag gaaagagtta tacaaactat acatcagcta
    13021 atattaccct ttcaagtggt gcctatggtt caactactat aaaatctaat tctggagcag
    13081 ttggagaaaa tagattatat gcacatgcca atttatataa caaaaatgga caagttgtta
    13141 aaaccgctga ttggaaatct aatggtagtt ctacttctac acttacaaat acaacaggaa
    13201 atagcttttc aaaaggtaca ttttatacaa aaggaactac taaagtatat aatggaaatg
    13261 gatatactac acaatctgca aatcaaagtc ctaatgtagt ggttaataat ctaggtacta
    13321 gaatttcaaa agaagagtta aaagaacgta tggatttata tgaaattaaa aatatgctac
    13381 cagcagtagg gattgataat ataagtggct atatttcaat ggatgaccta tatgatgaac
    13441 ctaattttcc tgaaactcca gaagaagcta ttacatatca aaagataaga gctaaagcta
    13501 gttatagaat gattccactt tatgataatg atggtaaaac aataatagga gagtatcgta
    13561 ttgattcagc taattaatgt aatgttacaa aattttatta atttataaat taaaaggcta
    13621 tgaattatag aaataaaatt ctattttcat agctttttat aaaattatat aagttaataa
    13681 atatagagtt aattaaaatt attttactta aactgaaact atatatgttt ctaattaatc
    13741 taattaatat agaatacagt aaaggagatc tacatgagaa aattatcatc atttaaaaat
    13801 ttaataaatc aaaatcaaaa tgataatgat aatatggtaa taagtgccat aaatggtaat
    13861 aagcatgcaa ttgaacaact tataaatgaa caaaaagagt atctatataa aacagcattt
    13921 ctatatacaa aagatgaaaa tgaagcaatg gatatatgtc aagagaccat ttataaaaca
    13981 attctaaata tacataagtt gcgggaacca agttgtttta aaacatggat gacaaaaata
    14041 cttattaata atgttaatga ggtaaataga aataaaatca aaatatttga taatgatttt
    14101 caaattgaat taattaaaga tatatcatat gaaaaattag aagaaaagtt agacttatat
    14161 agtgcaattg atctattaga agaaaaattt aaaacaccta taatctttca atattttcaa
    14221 gatatgacta taaaagaaat agcagaggta cttgagtgta atgaaaatac agtcaaaaca
    14281 tacttaagaa gaggtaaaaa aaaattatac gaaatattaa tgagggggga gatagatgaa
    14341 aaagttagat aatataaaaa tgcccgataa ttttgatctt gctatacaaa catctataag
    14401 caaagctttg aatg
//
LOCUS       DAEHWO010000100        13878 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEHWO010000100 DAEHWO010000000
VERSION     DAEHWO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13878
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.102"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            478..1128
                     /locus_tag="KNP54_003454"
     CDS             478..1128
                     /locus_tag="KNP54_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBF0894314.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            1342..2013
                     /locus_tag="KNP54_003455"
     CDS             1342..2013
                     /locus_tag="KNP54_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894315.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            2010..3140
                     /locus_tag="KNP54_003456"
     CDS             2010..3140
                     /locus_tag="KNP54_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0894316.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKLEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3560..4405
                     /locus_tag="KNP54_003457"
     CDS             3560..4405
                     /locus_tag="KNP54_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894317.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4405..5433
                     /locus_tag="KNP54_003458"
     CDS             4405..5433
                     /locus_tag="KNP54_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894318.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDDYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5436..6449
                     /locus_tag="KNP54_003459"
     CDS             5436..6449
                     /locus_tag="KNP54_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894319.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLYYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLF
                     FSR"
     gene            complement(6966..8216)
                     /gene="cme"
                     /locus_tag="KNP54_003460"
     CDS             complement(6966..8216)
                     /gene="cme"
                     /locus_tag="KNP54_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBF0894320.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8302..9048)
                     /locus_tag="KNP54_003461"
     CDS             complement(8302..9048)
                     /locus_tag="KNP54_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0894321.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9163..10185)
                     /locus_tag="KNP54_003462"
     CDS             complement(9163..10185)
                     /locus_tag="KNP54_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBF0894322.1"
                     /translation="MNKNNCLDLIFEKVNPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTYSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGAGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10185..12605)
                     /locus_tag="KNP54_003463"
     CDS             complement(10185..12605)
                     /locus_tag="KNP54_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBF0894323.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSYNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEVRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(12691..13611)
                     /locus_tag="KNP54_003464"
     CDS             complement(12691..13611)
                     /locus_tag="KNP54_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0894324.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
BASE COUNT         4890 a         1802 c         2184 g         5002 t
ORIGIN      
        1 aattaagagt gataagatta tatactttat aaatgtaaat atgacggata aaaatgataa
       61 atataataat atatatattt acattaggag ttttctatac tataattatt taaaactaaa
      121 tataaatgtt ggaattattt aggacttgaa attgtctaaa aataaatata agtgatgaag
      181 aggtgatgtg atgagattag atatggatag tatgttatat gtactaattt atatgacatt
      241 attggtatct atcattggaa gtatatttta tttttgtaaa gacctcttaa atcataaaat
      301 taagtatgtt ttaataagag acatatttgt aaatagaatt acatattctg aagaacggtt
      361 gcctaaacag tatatagttt ttcagaaata tgatatttgg aggtattgta gtttgtttta
      421 atttgaaatg aatctattat aaattctaaa gtttaaaaat aaaaaggaga gaataaaatg
      481 gatttcattt caagtatatt gcaaggatta ttaagtatat tatttaattt tacaggtgat
      541 tttggaattt ctattgtact tataacttta atagttaaat tagtacttat gccactatca
      601 ttaaaacaaa gattttctgt aaaaaaacag caagaattag ctgaaaaaat ggaacatata
      661 aaagaaaagt ataagaatga tactaaagaa ttggaaaagc aaatacaagt aagttctgta
      721 gaaagtatga agagtatgct gggatgtctt atagttttgg ttcaaatgcc agtagtatat
      781 gctttatatc atgtatgttt agatatgaca aaggaattta caacaattat aattccatgg
      841 attgctaatt taggtacatt tgataatttg tttatattac cttgtatata tacattaatt
      901 atgttagctt caaatttagt gaattatata ccatatttaa aaataaattc tcaagtaaag
      961 tttaacaaac aaatggctgt ggtgactacc ataacaagtc ttatactaac tgttagaact
     1021 ccagtagcca taggtctgta ctttataaca agtgcaattt attcattaat tgaagatatt
     1081 tgttttagaa tatattttaa tcgaaaaaat agaatagtga caaaataata taattattat
     1141 tagaaatatt ttagcctgct aacatagaaa aagttagtag gctattttta tctatgatat
     1201 caattccatt aagaatagtc taaaaaatac tatcaaaatg ctataaaaaa tactatcaaa
     1261 atactataaa aaaatagttg aaaaataaat aaattaatat aaactaaaat aaagcctaca
     1321 aaaaagaggt gataaataga aatggctaaa atactaattg tagaagatga aaaaaggatg
     1381 caaagtatta ttgtagaata tatgcaaaag ggaggatata cttgtataac tgctgatgat
     1441 ggagtcgagg cacttacaat attaaagagc aacaatatag atttaatgat attggatatt
     1501 atgatgccgt atttagatgg attttcagtg tgtagagttt cacgtgaaat gactaatata
     1561 cctattatta tattgacagc taaaggtgaa gaggaggaca aattaaaggg ttatgaatat
     1621 ggcgcagatg attatataac aaaaccattt agccccaaag tacttttagc aaaagttaat
     1681 gccttgttac gtagatacac tactgatatt cccaaaaatt cattgagttt aggaaagatt
     1741 tttattatgg tagcatcaag gcaagtgtat gtagaagata aattgattga tttaacatat
     1801 aaagaatttg aattattgcg tttatttatg gaaaacccta atcaagtttt ttccagagag
     1861 aaacttttaa attgtatatg gggatatgat tttgaaggaa acacacgaac tgtagataca
     1921 catataaaaa ccttacgcaa aaagcttggt agtgaaggac accatatagt tacattaatt
     1981 cgttcaggat ataagtttga ggttaaggaa tgaatagttt aagaaagatt atagaaaaac
     2041 tgaaaaatgt agatatttca aattggatta aacaaaattt tggactatat tcagttagaa
     2101 aaaaagtgtt tttactttct aaattatcag gagcgttaat tatattattt tatctggttg
     2161 ttgaagaatt ttcgataaac tctaaattag aattttggat ttggtttata atactggtta
     2221 tatttattat gagtattgat ttcttattgg gaaaatttat ttcagaacca atcacatcta
     2281 taaataaatc tgcaaaaagt atgtcccaac ttgatttttc taatccatgt actgtaaata
     2341 ctaatgatga atttggagaa ctttctagga gcctgaatac aatgtctaca aatctacaac
     2401 aggcattatc agacctagaa agtgcaaata ttcaacttga aaaggatgta aataaggaaa
     2461 gaatgctatt ggaacaaaga aaggagttgg tagatacaat ttcacatgaa atgaagactc
     2521 cacttggcat tatacgtgcg tatacagagg ggcttatgga tgaagttgat gaagaaaaaa
     2581 agaaaaatta tatgaatgtt ataatagaag aaactgatag aatgaacaat atgattgtat
     2641 cattattaga cttatctgca ttggaagcag gagtttctaa acttaaccca gagcgttttg
     2701 attttataga gtttgttgaa actgtggcag gtcgtctttt aattgatata ccagatgcca
     2761 atttttattt tacatatgat ttgccagagt atgaagtttt tgtagtggca gataaaatga
     2821 gaatggaaca agtagtagag aatctagtta ttaatgcaaa gaagcatgtt gtatataatg
     2881 gtaatttaga tttatcgatt acatgtgaaa atggcttgct tttatttgaa atttataatg
     2941 atggtaggtt tatagagcaa gatgagattt caaagatttg gtctaagttt tatcgtagtg
     3001 ttcaatctca gcgtacagga ggttcaggtc tagggcttgc aattgtttca caaatactta
     3061 caatgcaagg gttagaatat ggagtgaata atcgtgatag aggagtagag ttttatttta
     3121 tgattccaat tgatgaataa tttagtatta atttataaat tataagtatc tgatgtaaaa
     3181 tatttttctt tgtatatgta agcatttaaa gagaataaaa taaaaaaact taatgaaaaa
     3241 agcttaatga aaaagtctaa taaaaagctt aatgaaaagt cttgtttttc tgatgaaaac
     3301 aagatttttt attaagcttt ttattatttc acttcgattt cacaagagag acactctgat
     3361 ttcaccaaat agaaataaaa taggttaaat aaattaaaaa atagaagcgt aattaaataa
     3421 ggttacaagg gggagtactt atgaaatggt atacatggtt gactattata ttgataatat
     3481 tgctttctat tccgcttaaa attaaattta taaaatggtg ggatagacga caaaaaaatg
     3541 ataaaggagg ttatgataga tgataaaagt aggagagtta aaattttctt atggaaaaga
     3601 taaacagata ttgcatggac ttaattttga agtaaaagaa ggagaaatct ttggattcct
     3661 tggacctaat ggttcaggaa aatccacaac acagaaaatc ttaaatggtg ttttaaaagg
     3721 ttacaatggt cacgtatccc tttttggtaa ggaagttaaa gcatacacag aatctttata
     3781 tcaaaagatt ggtgttttat ttgaatttcc ttatttatat accaatttaa gtgcaattga
     3841 taatttagaa tatttttcgt ctttttatcc taaaaatcaa aggagagata tatatgaact
     3901 cttagatttg ttagagttta agaaagagtt tataaataag cctgtatcat cctactcaaa
     3961 aggtatgaag caacgtatta gtatggcaag agcattggta agtaatccaa agttgttatt
     4021 tttagatgag cctactagtg gacttgaccc atctggagct gtactatttc gtaagattat
     4081 tgaagaagaa cgaaaaaaag gaacaactat ctttttgact actcataata tgctagatgc
     4141 agatttaatg tgtaacaatg tggcttttat tgcagatgga aagattatgg taatagataa
     4201 acccaaaaat ttaaaaatga aaaatagcaa taataaagtt gaagtggaat ttgtatataa
     4261 tggaaatcga gatattgaaa ttgtagatat acaagagtta gaatctggaa taacttttaa
     4321 atatgatgaa atcttaagtg tacattcaaa agaacctaca ctagaagaag tttttattaa
     4381 atacacagga aggatgttag tgtaatgtac tctaaatttt ttaccttagt aaaaaaagat
     4441 ttttggatga tgatttatgg taaatttttt gtgctgacac ttggctctct catactttat
     4501 tcgtgttata ttaattttgg ttatgtaaag tttatggatg aagatagtta tcacaataat
     4561 gtatatctat ataatccaga gaatataagc atgagtgcat ctccattaat taatcaagtt
     4621 tcttctatag gtgaattaaa agcaaaactt gatgaagata caagtgcagt ttgtattgat
     4681 atgagttcca gtaagccgaa agtaatttta catgaaagta ttaaaggagt tgacgattat
     4741 agagctgact atgcattgtc attattatca tcagaaaaag accacaatag caaaatatca
     4801 gacaacaatg caataattca aattaatgat aaggatacat ctgagataaa acaaagaaaa
     4861 gacatgactt gtgagatttt attctttgaa attgtagcta ttggattttt agggattgcc
     4921 tctttattat ttaaagaaaa gcagatggga gtaatgcgta ttactggtat tttacctgta
     4981 aaaagaagtc tttttatatt atcaaagata tttgcttttt tgatatgtga cctatgtttt
     5041 acagttcttt tagtagtatt taatattgga ttttttgaag gaataaaaat acttccacaa
     5101 gtattagttc aagctagtat tttatcaatt attatgtctt tgattggaat aggatgctca
     5161 atgttattga gagattttaa gcaattttct cttatatatc ttgtggttgc tgtattcata
     5221 actacaccta tatttctatc tgcaaataca tcttttgaaa tagattggat taaatatcat
     5281 cccttctatc atgtttatag tcagcttaaa aatgcgtttt tcatgaattt ttcaaaagaa
     5341 ttagtttatt ttgtagtgtg ttctttgaca ataatagttc tatttttact tgtaaaatat
     5401 atttttaata aagagttggt tagggaggga taatcttgat aggattacgt taccagttaa
     5461 agagtataaa aaaagataaa atgtgtataa tttccttctt tttaccagtt gttatggcga
     5521 ttttaataaa ttttatggga acaattgata tatcttcatt aggagagata cgttttggta
     5581 tagtgaagga tacacttcct gtacaaacag agcagtggtt gaagaagtat ggtatggtaa
     5641 gtgtatatga cacaaaaatg catttaatac gtgaaattaa ggatattaaa acagacacaa
     5701 ttggagttgt tagagatggt aaagggataa aaactgtgct ttatggaaat gagattaatg
     5761 ctataaaaaa tgttggaaag acattgccag agatgtttag actaaagggt gatttaaaag
     5821 atgttgaggt tacaatattg cctaaagata gtattttaaa agagtttcaa aatgttttta
     5881 ttgccatgat tttaattact gctatgttta tgggatgcac ctttaatgca atgaatatta
     5941 tatctgaaaa agaagatgga atatcattta taaatgaagt tttgccacag agtagaagtc
     6001 agtatattat acaaaaagta tttttgggtc ttttatgtgg gtgtttatct tcaatgataa
     6061 ctgtatttat atgtttggat atttcaatat tagatatgat aatgatgttg ttactcgttg
     6121 tattttcagc atttatttca tcacttatag gtttatttat tggaaagttg tcagaaggtc
     6181 ttatggtagg aattgtttat attaaaatag taatgatttt atttataggt actcctttgt
     6241 taatatatct tctaggggtt aataccagtg gtatagggaa tttatactat ataatgcctt
     6301 cagttgctac atttaatggt attatggaga ttattaatgg taatgtcatt attatcaaag
     6361 atattgtaat tttggctgta cattgtgtag tatggtttat gatatatatt attttagata
     6421 aaaaaagaaa gttatttttt agtagataac tcagtataat tataattggg acaatttaat
     6481 aggtgattta atatactttg tatagtgtaa tttatgtagt gcaatttgta tactttaatt
     6541 tatgtagtgt aatagttagt tttattttat aattattcaa tataatttag taagaagttc
     6601 agtacaatta gagctactta gtggaaaact taataggtac ttaaactata taaatacttt
     6661 attttcctcc atttgtacta taaatttaat ttatgatata aatggaggta ttattatatg
     6721 atttgataaa tttcatcatt ataacctaca agtaaaggta ttattatata aagttaataa
     6781 agatagtatc aaaatattat ttgctataaa gagaggggct caaaataaag ataaacctat
     6841 ttttcaatgt tgaaatgata aaatatattt gatttcatat aaaaaatttt cttcataaat
     6901 taaaaagtcc attttaagcc ccctcatttt taaccagata aatcgagtta aactatttaa
     6961 atatattact cggattcatt tgacttagat attccttgct tgtaaaattg ttttgaatag
     7021 gggatagcca aagcaaaaaa taaaagtata atccctgcta tgattattaa attattaata
     7081 gaaattacat ctgccattgg tccgaaaatc atcataccaa gaggaataaa accagtatat
     7141 ataataatag gtaagctaag aactcgacct agcatttgtg gtgctacatg ctcttgcaac
     7201 atagtcatag ctgatgcttg aatgattgga attgaaaaat tcgtaaaaaa cataaatata
     7261 aaaaattgcc aagcttgtgt tacaagacct agaataattg aaaaaatagc ataggataat
     7321 attgctagaa aaaaggtctt atttctattt ttaaaaccac caaaaactcc tataatcaat
     7381 ccacctaaaa ccatacctaa aaatccaatc atttcaataa tagacaggta tatataaccc
     7441 ttgccaaatg ttcgttcaat aagaagtcct ataagaaatc ctgatggaac acaaagaagc
     7501 atgaatgctc cataagtaaa aagcactttt ctaatgaact tatctgaaaa acagtacttt
     7561 atccctgata ccatatctgc aaaaaatgag actttttcag tttgttttgg tatatcatgt
     7621 ttaggaattt tgatgaatat caataataca atagcaataa ttgcagtaaa tacatcaatt
     7681 aaaagaactt gatttatttt attaccaaat ccaagtattg cagcagctac aataggaact
     7741 ataaattgta ctatagattg taggctacta tttataccat taaaacgcat taaatgttct
     7801 tctggtacaa gttgaggaat cattgcgttt acagcaggtg tttgtacacc acttcctagt
     7861 gaacgtataa cagatattac tgatatggct attaattcac ttgttgtgcc atttgatgac
     7921 atcataaata gaattagaac taatgtagat atagcaattg ttgaatctga tacaattatg
     7981 agtacctttc gattgtagta gtctgcccat acaccagcaa aaaaagaaat tatcatttga
     8041 ggtataaagg agcatacagt taaaactgtt acccatacac ctgatgatgt ctgaagtgtg
     8101 acataccata tcattgccat ttgtacaagt gatgagccaa ataaggaaat atattgactt
     8161 gctaaaaaaa gaatgacttt tttcttccat gtagaattag tatttttgtt ttccatccta
     8221 ttcctccttt gatttgtgtg ttgaattttt cttgctctta aggataacac acaaatcaaa
     8281 gtctggagtt agagtggagg gctaggaaaa ttgttttttc ataatttgaa gatgagattt
     8341 catggttttt gcattatgtt cagcttcttt caatgaagtt atcagtttgt cacacactga
     8401 gataatttcg tcatcatctt ttggagtgtc aaggacagtt ttaatattag tattaggatt
     8461 agaagataaa gcatttaaca ttcgtaaaat agctgaaaga gaatagtttg cacaacgaag
     8521 tgcgcttata attttaagtc gttttatatc ttcatcagta tatacacgat aaccattttg
     8581 ttttcttttt acttttaaca aaccattcat ttcccaattt cttaaagtat ctattgtaac
     8641 gtttaagtgt tctgcagttt cttttctagt taaaaagagt ttatttgttt ctggagtatt
     8701 tccatttaaa atctgtgcaa caatagtaag tgcttcctcg gcattagatt tttctatttc
     8761 taattgttgc aagtattgat ttacaagact aatagcctta tcaaagtccc tattcgctga
     8821 tgttcttaca atctcaaggg catcttttct taatcccctt tgtaccactt caattttcaa
     8881 ggctgtacga gcaaatctaa attgttctat atgaaaatca ttaaagatac gataaccatt
     8941 ggtattacgc ttaggtttag gtattaagtt tagttcttca tataaacgta ctgtattagg
     9001 atgtacacca attaaatctg ctacctctga tgtcgtgtaa gtgtccatta gtattcaact
     9061 ccttttagat atatagtatt agtcataata acaccaaaca aaagtctggt gttataatgg
     9121 agggtttggt tatctaagag taattaattt atgaaagagt aattaatcta ttatagaagt
     9181 aagtatatat ttttcaataa actcccatct atcacgaggt ttaaacacta ttttagatgg
     9241 tatggctatt actaagtcat attgtggaat acaacaaata gcatttcctc cagctcccat
     9301 tgctgaatac cacaaaacac catctttttt acatagccac cacagataac cgtattcatt
     9361 actattcatt ttaactgatt cttcaatcca cgatttagat ataatacgtt tattattcca
     9421 aataccatca tttaaataca gaaaaccaaa tcgcaacata tctctagcac tcaatgtaag
     9481 tccccagcca cctatagaat aaccctgtct atcttttgcc caacccttaa gattttttcc
     9541 aaagaaatct tcaaaaccaa aatctttcat atcataatct ggtataactt tcataccaat
     9601 aggtttaaat aagtattcat tagcaaattc acgagcagat tttccagtag tttttgttat
     9661 aatagctgaa agtaggtgcg ttccagctga agaatatttg aaagtaccaa tttcgccttt
     9721 ttgaccaagt tgattcaagg tatattttat ccaatctttt tgtttgcaaa gtctttctaa
     9781 agactcagtc atatttttaa aagggtatgg tgcagtcatt gtaagtaggt gacgtatagt
     9841 tactgctttt ttacatattt cagaaggact ataagtatat tcagggaaaa aatcaacaac
     9901 cttttggtca acatctttta tatatccttt atctattgca atacctatta aggctgatat
     9961 aatacttttt gtaactgatg caacatgaaa agtatcatca gcattatatc cattatagta
    10021 cttttcaaag acaacttttc cttttcttgc aataattatt ccatttatat tactatattg
    10081 tgagattatt aaaggttcaa gttgtgagag tttttctgaa ctcatgccaa cacttgaagg
    10141 atttactttt tcaaatatta aatctaagca attgttttta ttcattaaag atacctccct
    10201 gttatagatt ttggattttc ttttagagtt tttggagaac cttctgcaat tatataacct
    10261 cctttgtcac caccttctgg accaagctca acaatccagt cacaaacatt taatacatct
    10321 atatcatgtt caacaacaat tacagaattt ccattttcaa ccaattcatc taataattga
    10381 atcaacttag aagtatcgta tagacttaga ccagtagttg gctcatccaa tacataaagg
    10441 atattaccat ttcgtttttt accaatttct tttgcaagtt tgattctttg ggattcacca
    10501 ccacttaaag ttggtgtagg ttggcctaat tttatatacc ccatacctat ttgttctaat
    10561 acatttaagt gtgaaacaat atttggaata tccttgaaga aatgtacaga ttcagaaaca
    10621 ctcatattta aaatatcatg tatattttta tttttatatt taatagataa agattcatca
    10681 ttaaatcttt ttccctgaca ttcactgcat atatggtcta tacttagatt atttcccaac
    10741 cagacctttt catatccact accactacat ttaggacaag cccctttgga gttaaatgag
    10801 aaatgaccag ctgtaaatcc tcgttctaac gattctggct gacctgcaaa tagtgtacgt
    10861 atcttatccc atataccaat ataagaagca ggagttgagt tcatattttt gccaatagga
    10921 gattgagata tctctgaata tccagaaata tgtttagtac caatcagtct atctgcaata
    10981 gtttcaacaa ctgcataatc gtcttcctca cctatttcac tctctgaaga atttatttga
    11041 ttattgatag tatggttatt aaattggctt ctaagaagag gaagtagggt gtctgatata
    11101 agtgaactct tgccactacc tgattttcca gatattccaa ccatagcacc caaaggtaat
    11161 gatacagtta catttttaag attatttgta tttgcatttt gaatagttat acaaggtatt
    11221 ttatcagtat gtgtaatgtt tttattgctt gttctattag gcattggata ttttccagat
    11281 agatactgtc cagtgagtga tttgtcggat tgaagtagac cttctaaatc tccttgatat
    11341 actaattgac caccttcaac accagctttt ggaccaatat caataatatg ttctgccatt
    11401 ttaattgtgt ttttatcatg ctcaactact atgaccgtat tgcctaaatc tttaagtttc
    11461 tttattgatt ttaagatgtc tattttttct gattcatgca atccagctgt tggttcatca
    11521 agcacataaa ttaatgagtc catctctgaa tcgagatgtg aatttaaaaa tagtctttgc
    11581 atttccccac cactcaaagt tgacatttct cggtataagg atagatgacc taatcgtgat
    11641 tctattaaat gttgagtttt ggataaaata tcatttacaa gatttgtacc aaatgtgttt
    11701 aaattacctt gatttattaa gagtttaagg aaatcatcaa tttctaaaat cgtcattttt
    11761 ccaagttctc caatatgttt tccgtttaaa agtactctac gtgcttcttc accaatttta
    11821 aaaccattgc aatctgaaca ggcagtcata gtataaactc catttaaatc ttcgcccctt
    11881 ttgtaacgat tgtgaaatac ctttgataaa gaggaacttt ttttaccatt ttcataatga
    11941 ccatagagta cttcatttct tacttcttca ggtagttgta agaattgtat gtctaaataa
    12001 tcattgaatt ttttagaaaa tactctcaaa tatccaggtg taatctttgc tctatctaag
    12061 acttgtttta gggtatcatg cttatcaagg actaattttt caatattaat ctcaaaatat
    12121 gcaccatgtc cagagcactt catacacatt ccatctgaag agttgtatga gaaataactt
    12181 ggtcttaatc gttcttcctc atatccacaa ttattgcaaa ttagattata gcttacagga
    12241 gtatcacaca tagtacacat tatttgacct tccactgaat acaatagtgt aagcatgttg
    12301 agaatattgg ttcttgtgcc tactgttgaa cgaggattgc tctggcgaat aatattttgt
    12361 tgaacagcta tagtgggagc taaaccttga atattatcaa acttatcttc actatcaata
    12421 cctgcaagta tacctaaaga ttgcagatat tgtttacgcc cttcctcaaa tacaatgtca
    12481 aacataaggc tagacttacc tgagccactg acacctgttg caacaacaag cttatctttg
    12541 gggatagaaa catctatatt tttaagattg tgtatctttg ctccattaat ttttatttct
    12601 ttcattggtt cacctcattt tatcaatttt atcaaaccgt aaaataggga tatattaatc
    12661 cttaatacaa gaatagatta ggtgaggtta ttaaaaaggt tctataggta aatatatatc
    12721 gaccaagtgt ctattttgag ggtgattgtg tgggttgtta agatatactt caaaagggaa
    12781 ggaggcacgt agcttataat taccatttga tagccattca ttatacataa aatcccacgc
    12841 atcactatat tcagattttg aaatatcaaa atgtcccaca agatattttc cagaaggtat
    12901 tatcatattg ccaagattgt cattctcttt gacaacaatg ttatctggaa tggtcatgca
    12961 aatactagtc cttaattgat gctcctgtgt aaattgtgga ttatcatgat aaatggctaa
    13021 tatttgtgtg ttttcaagtc caagtagatt ctgctcactt gcatatgtga ataaccgttc
    13081 taaaagtttt gggaaagtac tggttagatt accatatgaa ccagtatacc tagtgtaaat
    13141 agtattcata ttatcaagtt ctagaatttc aatttcacct ttaacctctc tagtattctt
    13201 acatttaggt tttgatatgc ttctattgta ctgagaaatt ttatatggtt ctttgcaatt
    13261 cttgctataa ttgtttctat attttatagg gcttatttta tagtaatttt taaatgctct
    13321 tgagaaaact gctgaatcag taaagccaaa gtagtgtgca atatcagtaa cagtcatgtc
    13381 agttctatga ataagaaaag cagttgcatt ttctagtttt agcctattta catattgtgc
    13441 caaagtttct ttttctattg ctttgaagat tctatgaaaa tgaaattttg aaaaacctgc
    13501 tatattagaa agttcatcaa gagaaagagg ttcatgtaaa tgttcttcta tatagtcttg
    13561 cactttgcaa atacgattta gatattcttt tttactttta gcatttgtca tatatagccc
    13621 tccttattgt gtaaaatgtg tatcaattaa tttatagcaa tatagtaata aaattttatg
    13681 tttttgtaat ttatgataaa taagatagcg tttaattttt tataattgat aaaagatatt
    13741 tataattaat aaaagatatt tataattaat aaaagatata agatgcctta tatttgtctt
    13801 tgcatataag tatagtcttc gtaataatta gtataccata gtgatttatt tttaattgtg
    13861 tatttatata aatacaca
//
LOCUS       DAEHWO010000101        13476 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEHWO010000101 DAEHWO010000000
VERSION     DAEHWO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13476
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.103"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            202..1278
                     /locus_tag="KNP54_003465"
     CDS             202..1278
                     /locus_tag="KNP54_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBF0894325.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1381..2223)
                     /locus_tag="KNP54_003466"
     CDS             complement(1381..2223)
                     /locus_tag="KNP54_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBF0894326.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2407..2979
                     /locus_tag="KNP54_003467"
     CDS             2407..2979
                     /locus_tag="KNP54_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0894327.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3142..3414)
                     /locus_tag="KNP54_003468"
     CDS             complement(3142..3414)
                     /locus_tag="KNP54_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894328.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3541..4413)
                     /locus_tag="KNP54_003469"
     CDS             complement(3541..4413)
                     /locus_tag="KNP54_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBF0894329.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4709..7816)
                     /locus_tag="KNP54_003470"
     CDS             complement(4709..7816)
                     /locus_tag="KNP54_003470"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBF0894330.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7909..8141)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8316..8843)
                     /locus_tag="KNP54_003471"
     CDS             complement(8316..8843)
                     /locus_tag="KNP54_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBF0894331.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8878..9663)
                     /locus_tag="KNP54_003472"
     CDS             complement(8878..9663)
                     /locus_tag="KNP54_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBF0894332.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9673..9930)
                     /locus_tag="KNP54_003473"
     CDS             complement(9673..9930)
                     /locus_tag="KNP54_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBF0894333.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9949..10407)
                     /locus_tag="KNP54_003474"
     CDS             complement(9949..10407)
                     /locus_tag="KNP54_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBF0894334.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10447..11151)
                     /locus_tag="KNP54_003475"
     CDS             complement(10447..11151)
                     /locus_tag="KNP54_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBF0894335.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11161..11796)
                     /locus_tag="KNP54_003476"
     CDS             complement(11161..11796)
                     /locus_tag="KNP54_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894336.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12177..13217
                     /locus_tag="KNP54_003477"
     CDS             12177..13217
                     /locus_tag="KNP54_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0894337.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
BASE COUNT         4306 a         2267 c         1587 g         5316 t
ORIGIN      
        1 tagacttaat ttattacttt tatagaattt tcacaataaa aagtcatttt acttccgtat
       61 ttaatgcaaa agtagaaatt aaacttaata taaaaaatat ataacaaatt ttttttatat
      121 ttctagaaga aaagtatact cttttttgtt taataatgct aaaattgatt tgtattgaat
      181 tttgattagg aggaaattat tatgaaagct caaagattaa atgctgtact tgaacaaatg
      241 aaaaaagatg atatttctca aatgttagta agtgacccta cttctatatt ttatcttaca
      301 ggagtactaa tccatccagg cgaaagacta ttagcattat acttaaattt aaatggcaat
      361 aataaattat ttataaatga attattccca gtttcagaag atttaggtgt tgaaatggtt
      421 tggtttaatg atactcaaaa tccagtagaa ataataactg aacatataga caaaaatgct
      481 actatgggtg ttgataaaaa ctggccagct agattcttat taaacttaat agaattaggt
      541 ggaggaagta agtttgtaaa ttcatcttat ataatagata ctttaagaat gtgtaaagat
      601 gaagaagaaa aagagttaat gagaatagct tcaaaattaa atgacaaggc tatggaacaa
      661 cttaaagcta ctgtttctgg tgaacttaca gaaaaacaac ttgttggtaa attatctaaa
      721 atatatgaag acctaggtac tgatggattt tcatttgacc ctattatagg ttttggacct
      781 aatggagcta atccacatgg tgaacctgga aatgcacttg tgaaaccagg agatgcaata
      841 atcttagata taggttgtat aaaagataac tattgtgctg atatgacaag aactgtattc
      901 tataaagaaa tacctgaaaa aggtagagaa atatttgaaa tagttcttga agctaataag
      961 agagctgaag ctattgtaaa accaggtgtt agattctgtg atatagatgc tgctgctcgt
     1021 gactacataa ctgaaaaggg atatggacag tacttcactc atagaactgg tcactctata
     1081 ggacttgaag ttcatgataa aggagatgta tcttctataa atacagatac tgtacaacca
     1141 ggaatgatat tctctataga gccaggtata tatttaccag gtgagttcgg agttagaata
     1201 gaagatttag tacttgttac tgaagatggt tgtgagatat taaacaaaca tgacaaagaa
     1261 atatgtgtag ttggttaatt ctaaaatcaa tttgataaaa ttaaaaagcc atataaaaat
     1321 gttttaaaca tttttatatg gctttaattt ctcaatctat gatttatttc aatccattat
     1381 ttatattgca gttattaaga ttgcaccctt tgaagtatat gtccccatca ctgaaccaat
     1441 ttcacagatt acaacatctt tgtattttac atccttttcc ataacttccc ttaccttttg
     1501 agccttttct gggcaattag catgtcctat aaataaaacc ttttcttctt tatctttaat
     1561 ttttgactct actaaagtaa tcagcttttt caaactgttt ccttcacctc ttgccttatc
     1621 tataggagtt acaacgccat ctgcaacttg tattatcgcc ttaaaattta aggtatttat
     1681 aatttttcct gctattggat ttattctacc acccttaata gcattttcta aagtttcaag
     1741 tgttccaaaa aatggaggat tatctttata tttatttatt attgaaacaa tctcttcaat
     1801 ttcttttcct tcttttatta atattgctgc ttttaacact aattgtccta ttccaattga
     1861 cccactaagt gaatctataa cctcaacttt cttgttattt ccttcctttt caaacatatc
     1921 ttttgctaaa agtgcactat tataagtccc agataatcct gaacttatat taatcactaa
     1981 tacactttct tcctgacaat ggtatgcttc taaaaattta tcaggagaag gacatgatgt
     2041 ttttggtagt actttactct cactcatttt tctatagaaa gtttcattat ctatttcctt
     2101 tccagatata taactttctt ctccaaaaga tacatttaaa ccaacaactt ctatgttgta
     2161 tttttctatt atatcatcag gtaagtcaca tgcactgtcc actatcaatt ttattttatc
     2221 catattaacc tcactataag atattatttt atttattcag tcggtcgtac gaccgattta
     2281 attattattt tatatattga atgaaaaaaa gtcaatagat atagattctc gctttattga
     2341 caataaatat ccataagctt ataatgttat taatttgtta taaatataca tggaaaggta
     2401 ggttttatga aaacaaataa tatgaaacag gctattttat catctgcaac caatttaata
     2461 gccaaaaatg gagttcaaaa tactagcctt gctgatattg caaaagatgt aaatataagt
     2521 aaaggtactt tgtattatca ctacgcatct aaagatgata ttatatatga tattgcggat
     2581 actcatttag aagttataac tagtgctata ctaaactgtg taaaaaatgt caaatcaaaa
     2641 aattctcaaa tagaaatggt taacttaatc ttagagaaaa tatctactat agaaagtcgt
     2701 ggtagggtac atatgtatct tatttgtgag gcaattactt caaataatga tttaaaggaa
     2761 agaataagat taaaatatat tgaatggaga actactctta aatctgaaat tgttgaatca
     2821 ctagaaaaat ataatagtag cgaaaatgaa caggatgctg aatcattttc ttttttactc
     2881 atgtcaatag ttgatggttt agttgtccaa agtttattaa aaacagaaaa aataccttat
     2941 gaaaatatag cttctttttt agttaatcat tggatttaaa cttaatactt agataattaa
     3001 taaaagtgaa ctatttaagt tatctacttt aacagttcac tttcttattt attctcaata
     3061 atttttactt aaaacattca atttttattt aaaccttcat ggaatcacaa aataaaaatc
     3121 tcttataaat ttaaaatgtt tttatttatg ttcatgtgta tgcccatctg aatgttcatg
     3181 accatgtgta tgtgtatgct catggctatg ctcatgagta cctgaaaaac catcatcatg
     3241 attatggtcg tgacctacac catttacatg ctcatgttca tgcccatgac tgtgagaatg
     3301 ttgatgtgaa tgttcatggt tatctcctcc acagcatcct tctcctccag tcccacaaca
     3361 cccacttgta tgtggattat gatgatttct tactacaaat ctctctctta acataattct
     3421 tatacctcct agtatattat tgagtacttc atgtacccca ttaactacag tatacatcta
     3481 actaggtata atctcaatac atatggcatt ttttaacata tataattaac atatataatc
     3541 ttaaagaaat ttatccttaa aacctccacc ttttacttct tcaacgttat tgacagaaat
     3601 aaaagcttca ctatccatat cataaattaa atctttaaat ttacctattt catttgcaga
     3661 tattatgcaa taaatcatct ttttcttatt ttgtgtatat gcaccttctg cctccaaaaa
     3721 agtgactcct ctacccattt tattcattat cactttggat atttcatcat atttatttga
     3781 tattaaaagt atagattttt ttctatcaaa gcaatctttt cctatatcca tagtaaaaga
     3841 aattatatac attgtaatta aagtgtacat caccaattta gctccaaata aaaaagctcc
     3901 tgcacatact acaaaaaaat taataaataa aaatgtattt ttcataggta tatcatactt
     3961 tcttttcatt atggctgcta ttatatcaag tcctccagca gtagctcttg ctttaaaagt
     4021 taaccccata cctataccag ttaatgcacc accataaata cactgtagca tagtatcatc
     4081 tattgggaaa tatttagcaa tatcttgtgt tagccccagt gctagagaaa atagtaacat
     4141 attgacaaaa cttattagca aaaatttatt atcaaaatac tttctagcta taataaatat
     4201 tggtatgttc atcaagaaac ttgatattcc ctgattaata ccaaataatt tgtataatat
     4261 aacacaaatt ccagctactc ctccacttaa taacttggct ggtgctagat ataaatttat
     4321 tcctaaggtt gatagaatca tacccaatat aataagacaa tattgtaaaa atatattatt
     4381 atcaatactt agctttttac tttcaccata catcaaaacg cacccctttg cataataaat
     4441 aaaccaccct gcataacaca cgataaattt acaaataaat ttatcagaag tagtttccta
     4501 aaaatattat tcatcctcac ttaaacgttt attcattaat attctatcac atgacataaa
     4561 taatttatat gatttatata gatttattta ttgtaaattt tggaatatta aaacatttta
     4621 ttgaatagat aattatatta cataaaaaat ccctatagaa atctataaac taatttctat
     4681 agggattttg gttaactaac tattattttt atttttttat aacttttata cctgtcatat
     4741 ggtcatttaa gttttgttcc tctaaagatt tatcatctac tctgtttatt tctaaagcta
     4801 aagtttcaga cttgatatat tcattaaaat ggtcaacagc cttagcaatt tcatcatcac
     4861 cacagtattc tattactata ttatctaata cttcaaagtt attagatttt cttaattgct
     4921 gtactttaga tataaattct ctagcataac cttcattaat taactcttca gttagcttag
     4981 tatctagtat aacaaaaaga ttgttttcaa cagatacatt aaatccttcc ttagcagtta
     5041 tacctattaa tactaaatcc ttattaaatt caaaagcttc accatctaaa tcaactgtta
     5101 aagtctcacc tttttcaagt ttattagcag tttcatgagc atttaattta cttaatgctc
     5161 caacgaataa attcatctta gaacctaata atggccctgc ttccttaaag tttggtttta
     5221 aactaaagtt catatactca tctaaatcct tagcaaatat tacctcttta acattaagct
     5281 cttcttttat taaatcaact acatcactta ttgtatcttc aaacttacca tctactaaca
     5341 ctttttgtaa tggttgacga acttttattc tttctacttc tcttgaagct ctacctaaag
     5401 taactaagtt tttagctaaa tccatttttt cttctaattt agtatctact aactcttcat
     5461 tacatttagg atattcagct aaatgaacag atacttctcc tgttaagttt ctatacattt
     5521 cttctgacat atatggtgca aatggagcta tagctctaca aagaccatgt aacaattcat
     5581 aagttgtatt gtacactgct tttttatctt ctgttaattc agttgcccag aatcttcttc
     5641 ttgaacgtct tatataccag ttagataaat catcatttat aaaatcttgt atcattctta
     5701 aagttttatt taactcaaat atagctaaat tttcttctac atctttcatt aaattattga
     5761 acttagataa tatccatcta tcaagttctg gtctatcttt atattctaca aaaaattcag
     5821 ttggatttat atcatctgtg tttgcatata aagtaaagaa gttatataca ttcttcatag
     5881 tacctataaa tttactttgg atttctttta atccatccat atcaaattta gttggagtcc
     5941 atggtggaga aacatatagt aaataccatc ttaatgcatc tgctccatat tggtcaaata
     6001 attccattgg atttactgta tttcctcttg atttactcat tttcttacca tctttatcaa
     6061 gtacaagatc tggaactaaa acactcttat atggtgcttt tcctaataca aatgttgata
     6121 ctgcaagtaa tgagtagaac caacctctag tctggtctat accttctgat atatagtcag
     6181 ctgggaacaa ttggtcaaag ttttccttat tttcaaatgg atagtggtgt tgagcaaatg
     6241 gcatagcccc actatcaaac caacagtcta taacctctgt tactcttgtc attggttttc
     6301 cacatttttc acattttaag tgtatatcat ctacatatgg tctatgaagt tcaactgttt
     6361 ctggatttac atcttctata gctttttcag ctaattcagc tcttgaacca actgaatctg
     6421 tatgaccaca ttcacatctc catataggaa gtggagttcc ccaatatcta gttcttgata
     6481 ttgcccagtc atttagattt tctaaccagt ttccaaatct cttctctcct acaaaacttg
     6541 ggaaccattt tacaccatta ttattttcta ttaatttatc tttaagttta gtcatctcta
     6601 tataccagct tggttttgca tagtatacta atggagtttg acatctccag cagtgtggat
     6661 aattatgaac tactttttct ttgctatata atttattttc agaagctagc cattttatta
     6721 tttcaacatc tagcccatct tccattacaa atctaccttc ccaaggagta gatgtaaatt
     6781 taccagtttc atctactggt tgaataactg gtaaatcata tcttttacct gtgttgtagt
     6841 catcttcacc aaatgctggt gctgtatgaa ctataccagt tccatcttca gtagttacat
     6901 aatctcctac tgtaataaaa aatgcttttt tgtcaacttc tacaaaaggc attaattgtt
     6961 catattctaa accttctagg tctttacctt tcatttcttc taaaacttca taatcttcac
     7021 ctagtacttt atcagctaaa ggtttagata cataatatac ctcatcacct tttttaactt
     7081 ttaaataatc tacatcagca tttactgtta atgaaacgtt tgatggtaaa gtccatggag
     7141 ttgttgtcca tgctaagaag tattcatcag catctttttt cttaaattta gctataactg
     7201 tattagtttt tacttcttta tatccttgtg caacctcatg actagcaaga ccagttccac
     7261 atcttgggca ataaggaagt attttatgtc cttcatatat atatccttct ttgttgaatt
     7321 tgtttagtat ccaccataca gactctatat agttattatc taaagttata tatggattat
     7381 ctaaatcaac ttcataagcc attctctcag tcattattct ccattgtttt tcaaatgaga
     7441 aaactgactc tctacatttt tggttaaatt cagctattcc atattcttct atttgttgct
     7501 tgctagtaag acctaactct ttctctactt gtatttcaac tggtaatcca tgtgtatccc
     7561 aaccagcttt tctctttact tgataaccag acattgtttt atatctacaa actgaatctt
     7621 taagcgttct agataaaaca tggtgtactc caggatttcc attagctgtt ggaggtcctt
     7681 catagaatac gaaacttggg tcatctttcc ctttttctaa agttttttca agtatattta
     7741 tgtctttcca ataatcaaaa acttgtgctt ctgcttgttt tacagaactg tctaccaatg
     7801 gcttaaattt cgccatgtaa atcacccttt cctactaaat attataattc caaaattttt
     7861 tattctttca cataaattta aatactaaaa aactcgcccc ctttaaacca aagggacgag
     7921 ttataaatcg cgttaccacc ctaattctat atgtaaacta aatactagct acatataaca
     7981 ctctaatagt ataacggtac taaccggcac agcttagtag aatttaatcg ttcagcctgc
     8041 agctcaagag tgatttttat ctttataaat tcattggttc tcagcatacc caattctctg
     8101 taaaattatc taaagataaa tgtctctatc aacgctttta aaaatttatc tgtgtttata
     8161 tgaaattcta taacaaataa tttgaatagt caatatattt ttgaaaaata taataatttc
     8221 tatttttctt acatttttat cctattttta atctttgtta tagatttctc aaactcacac
     8281 aattattcta cataaaaaat aaacaaatta caagcttatt ctaaagttgt agcagcttca
     8341 tcattactat aattatacac tgttgttcct tcaaatgcat ttacacattt ttcatctaca
     8401 tcataaaaaa tctcatcaac acttcttatt tcatcttcta acagtgattt aaatttattt
     8461 ctaaatatct taaattcttt gactaaagca tcatactctt ttcttatctc tataacacgg
     8521 ttattagctt gttctataat ttgtctagct tttaaatcag cttcttcaac aattatctta
     8581 gcctttttat tagccgcgct acaagtgtct tctgctgcac tttgagcagt tattaaagta
     8641 gcttttagtg tttcttcaat attttcatac ttgtttactt ggtcttgata taaccctaat
     8701 ttttctttaa gagctgtatt ttccctacat agagattcat aatcttcctt gatgatatct
     8761 aaaaattcat caacctcttc atctctatac cctcttaaac cttttttaaa ctctttattt
     8821 tctatctcaa ttggagttag cattacattt cctcccagct ataatttaaa ttagtcctta
     8881 tacaattaat cttgcttgaa cttttatttt tcctttttta gtaatatctc ctatttgtgt
     8941 taccttagct cttcctttgc ctctaataga aatcaaatca tcgtttttta ctattttaga
     9001 agttgaagtt atcttttcat aattgacatg gactttttct ccatttatgt attttgcact
     9061 atcttgtcta gatatattgt aaataccact tatcacacaa tctaacctat ctgaagatac
     9121 tgtaaatgat acttctttat attttgaaga actattaaca atattttctc tggaaatttc
     9181 ctttacaatt acattatttc ttgaaacctt ttctaagttt acaattataa aatcgcaaat
     9241 atcactactt acaactactt gacaaaagct atcatgtata attatatctc caattttttc
     9301 tctttttata cctagaccca gtattgaccc taagtaatct ttatgagata tatttttaaa
     9361 tttgaaattc ccttctattt gtaaaaatct aagagtatct tctatatctt catattccat
     9421 gtaaaatgga taaataaata cagtgcttct ttcagcttgt tcataacctc catccacact
     9481 gtattttatt tcatttgtag aatttaatat tgctacagca tttttcactt catatggatt
     9541 aagaaactcc gtagacttaa catcatagtt ttttatacaa ctattagcct tgtctatcac
     9601 tttaaacatt ttatttttca agtctatatc ctttatgtga tttgttagtt ttaatttatc
     9661 catcctatca ccttagaata taaccaatac taattgtctt aggaacatca ataatactat
     9721 tgcaattaaa ggagaaaaat ctataggtcc atttgtatat ttatacatta tagaccttat
     9781 tggcccttct attggctctg taagattttc caaaatatca aaaattttac tttgtcttcc
     9841 atttggaaac caagtcatca agctttttat aactatcatc catgctatta tatctaaaag
     9901 ataataaagt gcaattctta ttgttcccat atattaaccg cctttttact atttattttg
     9961 ccaagggaag aatgctttac tttctaattc ttttttcata tttgcatcta tatccacatt
    10021 attaggagct agtataaata ttgatttaga aaccttttgt atacttccat ctaagacata
    10081 aactgcccca ttcataaagt taaatataga tttacgaact tcagaattag tcaatccttc
    10141 caaattcact ataactgccc ttctttgttt tagatggtct gctatagttg cagcttcatc
    10201 ataaacctta ggttcaacta ttacaacttt catttggcta gttgtatgta aatttacaat
    10261 tttatttgct tttgcagtac taaagccact gttcatttct tcttcttgaa ctatatcgtc
    10321 catgccactt tcatattcat cttcaatgta atcttcttct tcatcaacta tccaattctt
    10381 aaatttagat attattccat ttgacattat taacttcctc cttaaaattt attcaaattt
    10441 gagtaattat tttttattgt agtttctttc tccaaagatt gatgttccaa ctctaacaat
    10501 ggtagcccct tcctctatag caatttcata atcgtgactc attcccattg acaaaacatc
    10561 catccctaca ttagggatgt ttagttcttt tatttgtttt gataaatctt taagaccttt
    10621 aaatacacct cttatctcat cttcatcttc tataaaaggt gccattgtca ttagaccctt
    10681 tatttttata tttttatatt tttctgacac ttctttgaca aagtctacaa cttcttctct
    10741 atcaagtcca tgcttagact cttctttaga tatattcact tgtactaagc aatctatttc
    10801 tctgtttatt tgttctgcac gtttttgaat ttcttcgcat aatgcaattc tatctaaaga
    10861 gtgtatcata caaactttat cgattatgta cttaacttta ttggtttgca aagttcctat
    10921 caggtgccag tttaatttat cacctataat atcatacttt ctagctaatt cttggggttt
    10981 attttcacca acagaagtga ttccttccct cattgcctca ttaactaagt ctacatcaac
    11041 agtctttgtg actgccaaaa gggtaatctc tttgctgtct ctatctactt tttttgcagc
    11101 tttatcaatt ttgtttctta tctcagacaa attatcttta atagaaccca ttattatcac
    11161 ctactttatc cttatatttg tgtttatact gttaggtctt aaaattattt tgtcatatag
    11221 attaacactt gtaactccat ttatgtcatt tttataataa tccacaaata cagaagattc
    11281 attctcataa gttattcctt ctaatatgac aaattttaca ctttgtgatt gttcatcaat
    11341 tacatataca ccacgtttat tgtcttttgt ttttatagaa gttttaggta tttttaaaca
    11401 ttccatctga ttatatatta tatcaaattc ttcgacactt gtatcctgat ttgcaacaat
    11461 ttggttactt atttttaatt ttaccattat tttattatta ttttcatata ttttgtaaac
    11521 ttttgcatct agtttttgct catgatattc aattattaca ttttgatttt tttcaaagtt
    11581 attagaatct tctttactga tgtatgtaga tagataatta ctttggtcat tggcatcttt
    11641 ttctatagtt ccttttacat gaatctttgc atcaactttt tcatttttta acaccaacgt
    11701 atctacattt ttgctaatta tcattactaa tatattaaat actaaatata taagaatacc
    11761 aagtatcact aatctggtat attttacctt tttcaaagac tctcccccta taaaattact
    11821 ttcattataa gtacttcttc taaaaaatgt ttattccttt tttataagat aatattttac
    11881 gttctaataa ttattttttc catattaaat ttatttttta tcaatcttcc tatacaagac
    11941 tgcattattt atatataatt gtattataaa gtataagttt aatttacatt ttatacgtta
    12001 agcttacttt atatattttt atagttattt ttatttttag atgcaatata aaaccaatta
    12061 agatttaaaa taacttttgt tatgttgaca tttatttagg taatcattta tgaattagga
    12121 taacgttatc acaacaaaag tttatgtcct aaaaaaaata caaggaggat tttcttatgt
    12181 cagaaatttt attaggaaca ggtttacttt tattggttct atgttgtttc acaattttta
    12241 gttacaaggc cccatatggt atgaaggcta tgggagctct agcaaacgct gcatgtgcta
    12301 ctttcttagt agaggcattc aacctttctt tacttggtga tgttttaggt atggaatttt
    12361 ttagaagtgt tggagctgct aatggtagtc ttggtggagt tgctgctgct atacttgtgc
    12421 ctttagcctt aggtgtatct ccagtttatg cagttttaat aggattatct tgtttagatt
    12481 tttctatatt atctggattc gttgctggat actttgtttc tttcttaatt aagtttatag
    12541 agaaaaaagt gccacctgga gtggatttag tggttgtaat tcttctatgt gcaccactat
    12601 ctcgtcttat agcatcaaat gtagacccat tagttaatag tacactacta caaattgggc
    12661 aagttttgat agaagctacc aacattagcc ctataataat gggaattata ctaggaggtc
    12721 taataacagt agttggaacg tctccactta gttcaatggc tcttacatct ataattggtc
    12781 ttactggtct tcctatggca ataggagcat taggtgcttt tggttcagct tttatgaact
    12841 caacactatt tgcaaaattg aaattaggtt ctaaaaaaga tattatatct gttgctattg
    12901 aaccattaac ccaatcagac ataatttcag ctaatccaat acctatatat tctactaatt
    12961 tctttggagg agccttttct ggtatcattg tagccttgat gggtcttgta aacatgacac
    13021 caggtacagc tacacctgtg gctggttttg ctataatgtt tgcttataat ccagttcaac
    13081 aagttcttat aacagctggt ttatgtgctt tattcaatgt aattgcagga tttttaggtt
    13141 caaaaatatt cagtaccttt aaagttctta ctgctggtga aatacgtggt actgatgtag
    13201 aagaagaaat tgcttaaaaa acaataagat ttataaattt atatctcaag tagtagagtt
    13261 ttatattgta ggcaatttta ttaattgcaa acgttttatt ttttatttat gtttatgatt
    13321 attatgtgtg ttgaatattt agataaattt ttatttatta tttttattta gatttttgtt
    13381 tagtttttta tttggttgat atattaggaa taaaaattag tatagtttat tactagttag
    13441 atggcataac tttttagata cataaaaaat tttata
//
LOCUS       DAEHWO010000102        12912 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEHWO010000102 DAEHWO010000000
VERSION     DAEHWO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12912
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.104"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(25..462)
                     /locus_tag="KNP54_003478"
     CDS             complement(25..462)
                     /locus_tag="KNP54_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBF0894338.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSIPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(719..868)
                     /locus_tag="KNP54_003479"
     CDS             complement(719..868)
                     /locus_tag="KNP54_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBF0894339.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(881..1111)
                     /locus_tag="KNP54_003480"
     CDS             complement(881..1111)
                     /locus_tag="KNP54_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBF0894340.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(1970..2191)
                     /locus_tag="KNP54_003481"
     CDS             complement(1970..2191)
                     /locus_tag="KNP54_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBF0894341.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2771..3028
                     /locus_tag="KNP54_003482"
     CDS             2771..3028
                     /locus_tag="KNP54_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBF0894342.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            3497..4735
                     /locus_tag="KNP54_003483"
     CDS             3497..4735
                     /locus_tag="KNP54_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBF0894343.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYITYDG
                     SVRERKKYENVRYWNPICEI"
     gene            5519..6820
                     /locus_tag="KNP54_003484"
     CDS             5519..6820
                     /locus_tag="KNP54_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBF0894344.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            6896..7171
                     /locus_tag="KNP54_003485"
     CDS             6896..7171
                     /locus_tag="KNP54_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBF0894345.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            8506..8736
                     /locus_tag="KNP54_003486"
     CDS             8506..8736
                     /locus_tag="KNP54_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0894346.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            8729..9310
                     /locus_tag="KNP54_003487"
     CDS             8729..9310
                     /locus_tag="KNP54_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0894347.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(9889..10566)
                     /locus_tag="KNP54_003488"
     CDS             complement(9889..10566)
                     /locus_tag="KNP54_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBF0894348.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(10755..12119)
                     /locus_tag="KNP54_003489"
     CDS             complement(10755..12119)
                     /locus_tag="KNP54_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0894349.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYVARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            12247..12768
                     /locus_tag="KNP54_003490"
     CDS             12247..12768
                     /locus_tag="KNP54_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBF0894350.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         5012 a         1392 c         2058 g         4450 t
ORIGIN      
        1 ttaataaatt actttagatt tttattaaat gtttagcttt tctttaatat tttttatata
       61 acgacgattt ataataactt tttcgttgtt ttttaaagta gcttgcatgc gattatgtga
      121 tattactttt atacttttta tgtagtccat atttaaaatc atggatttag atattcgtga
      181 gaaagatgta ttagctaata attttgataa tttatatatt tttaaatcaa tttcaaatac
      241 atcatcttca taataagcaa atgttttatt tccaactgtc tcaaagtata aaatatcaca
      301 gacattgagt ttataaatct ctcctgattt tttacctttt atatcaagta acggtatact
      361 caataatgaa attatttttt caatgttatt atctagagca gaacatttta tggttatttc
      421 aatatcatca caattaatac cttgttcgac atgtattttc attaatcatc acctcatttt
      481 attactgtca ttagaatagc attatatctt attgagtcca actagatgcg ttctaaattt
      541 caaattaagc atagtgaaat tcaaaaataa aacagtgaaa ttcaaatttg aggtggtaaa
      601 attcaaaaaa atactatgga tatttggata aattatccaa atatcctagt atttcacata
      661 gaatatgtct aattatttta caaatagacc tattttatga cttacatata ttgtcaaatt
      721 acttcttaaa tatcaaaata tttttggata atgtatcaat actgtttgat aaagtattta
      781 atttaccctc aattctaacc aacaagtaca tggatagagc tataggaaaa ccaacattgg
      841 ttattaacag ttgtaaacta tcatccataa aattagcccc ctattctata actaagtcat
      901 aaggagtggt atttgtttcc acaaccttgg cttcaacaac agaagctagg tcaaatcctc
      961 caaccgaaaa aatattttta gatactatca aatccatgac agattttata ttttcttcag
     1021 ttaaatcatc ctttggattt tctatagaaa aagaaacttg tttatccttt acatttttaa
     1081 agctcatgac taattttttc ttaatttcca tataattacc tccgatataa taatttatat
     1141 tttaattgtt tgcttgttaa tattggtatt ttaattatca atattaatgt tttgcttgtt
     1201 agtattaata tttcaattgt caatattaat gttttgcttg ttagtattaa tatttcaatt
     1261 gtcaatatta gtgtcttgct tgttagtatc agtgtttcaa ttgtcaatat tagtgttttg
     1321 cttgttagta ttaatatttc aattgtcaat attagtgttt tgcttgttag tattaatatt
     1381 tcaattgtca atattagtgt cttgcttgtt agtattaata tttcaattgt caatattagt
     1441 gttttgcttg ttagtattag tatttcaatt gtcaatatta gtgttttgtt tgttagtatc
     1501 agtgtttcaa ttgtcaatat tagtgttttg cttgttagta ttagtatttc aattgtcaat
     1561 attagtgttt tgcttgttag tattagtatt tcaattgtca atattaatgt tttgcttgtt
     1621 agtattagta tttcaattgt caatattagt gttttgcttg ttagtatcag tgtttcaatt
     1681 gtcaatatta gtattttaat tgttgactct agttattgct gatatagaaa atatttaatt
     1741 tatttcaatt aattagatta aagtagggta gcatctaaaa tagctaacat gtttaagttg
     1801 aaatacgttt aatatattaa tttttcaaag cgttaatata ttaaagttat aaccaaaatt
     1861 gaagttataa tctgccaaat ctatagcgta ttaagtgcat tatataactt aatcttttat
     1921 ataaagagtt aattttttaa tttgtaaagc agagtacgtt taaaagacac tatttagata
     1981 gtgatgtact atctaatttt aaaatatcta caatagggtt ctcttgaaga cttgctattg
     2041 cttctgcaac agcataaaca tcttcattta atgcctctgc ttttacattt gcaaatgatt
     2101 tacttttaac aactgcctta cccttatcat caaaaccagc atccaatttt agttttatac
     2161 tagataaatt ttttgttgaa acaacttcca taaaattacc tcctaaaaat ttaatttcaa
     2221 agatttgtcg actttctttg ttagctataa tactatcatc taagataata tcggagttaa
     2281 acagtaattt ctaaagattt tttgtgtaaa tttttatagg aaaaatttta cttttttgct
     2341 gatgaaaaag tttacaagtt atttgtgaag atatgttctt agtgttttga aatagtattt
     2401 gtatatattc atgcttagtt gagatagttt tgtatggatt ttcatatgtg tagagttaaa
     2461 tgttaggtac taaagtttat gttaaattaa atgttaaagc ttatgttaaa aattttatta
     2521 aatttaatct gtaaataaaa aagttaaaag tccaatatta acattttact tttaaaccat
     2581 taaaatcttt attaaagcta acaaagttat aagttatgag aaattttatt gaagttaata
     2641 caaaaattaa ttttaaagct aagaaatttt ttattagatt caataaaact aataaatata
     2701 gtttagtcaa taatgtatta aataaaaact ttgttaagtc tataaaaata tcttaaagga
     2761 ggtgtaactt atgaagataa aagtggagga tataccagtt caatttcatg caatggtaga
     2821 aataatcgga attgataagt tcatagaggt tgccaagttg tatggaggaa caaatactta
     2881 tatacctacg tataaggggc tttttagata tgctagaaat agggatatag taaaacaatt
     2941 taatggagtc aaccacaatg aattggctat tagatataat atgtgtgtaa gcaatattaa
     3001 gcgaatactc aatgaaaata gtgtttaaat ataataaaat aatgtttaaa cataatgaaa
     3061 atagccttgt taaacgtaag agtaaagaca aagaagatgt tttataaagt ttttttagac
     3121 aaattaacta aatttactac ttattaattt aaatacattg tatattctat aaaaaaattt
     3181 gttaaatact ggagatatat tgagaataca aagaaaatgg tcgaaaatat ttgttggcta
     3241 aaaaatagat aaaatgatac aattgcttgt ataaagggga aaaataaata aataaactat
     3301 ataaataaag aaatagcaat taatatgaca taatatattt ataaaattaa gaatataaat
     3361 agatatttta agggattagt tgttaaatta ggaaatatta aaaaaaatat atatttatat
     3421 ttaaactatt ttgttattta tataaaaata cttatctagt tactagcaat tattagtaga
     3481 aatgggggaa atagagatga ataagggatt ttacaaatta aattcagtgg tattgaactt
     3541 tgatattaag aatgatgtta acaagataag atttaatcat tatataatga gaaaagaaaa
     3601 catacaaaga cttcaaggaa ctctgccaaa cggacaattt tatatgacag tgagaagagc
     3661 tgctacagat ttacaacttt ctatttctac tataagtagg cttgtaaaag agtttttgga
     3721 tttagggata ataagattag tgtctaaggg tgtaaaaggt aatcgttctg tatatagtta
     3781 cgtaagtata gagtttaatg gaagtttatt tgatgatagt aaatatatgg aacttgactg
     3841 tgtatgtaat gatgaattta ttgataatag tggcatagag tttgattgtg atagcaaaga
     3901 taattctttt aatggagata taaatgtaga aactgtgcat tgcattaatg agtatttctc
     3961 tgatgatgat gtagagcata attataacaa tttccataac aaagatacta taaaggataa
     4021 agccatttct aatattagca ctatcaaaaa atatattgat gaatcttttg atacaaataa
     4081 atcagaaaat tctaacttac aacaggagtc aataaatttc aactttaatg atacatgcaa
     4141 tgaaatagat aaaagaacga ataatagtat agaaaataat caaaataaaa ggcctatgag
     4201 attgagtgac atcagtcttt taagtgataa aggtatgaca aataaaaaga attactttaa
     4261 tcataatcat ggtatacaaa aagggactaa atctgtaaca aagaaaaaag aatccttaaa
     4321 taaatttaat aaaaaaaata tacagcaaag cattataaat atgctaaata aaaaatcagg
     4381 taagaatttt aaaatcgatt ctccaataag cataaaactt atcaatgaaa ggctaaagga
     4441 aggctatgtc ttagaagatt tctacaaagt tattgaggta aaagtggcta agtggaaaaa
     4501 taccataatg gaaatgtata taagaccaga aactttgttt agctataagt ttgaatccta
     4561 tgtaaatgaa aacatatcta tgaaaagtca aagtaatgtt cacccatgta aagaaggcaa
     4621 tagtaatgat agcagtaatt atatacattc tgattatata acatatgatg gcagtgtgcg
     4681 tgagagaaaa aaatatgaga atgtaagata ctggaatcct atatgtgaaa tttaattagt
     4741 ttaaaaatgt atttatgata aataagatat taatagagaa tagtgagcta tagcaaatga
     4801 tatatcaata gttggtagta agttatatta agtaagatat tactatcagg tagtgaatta
     4861 tattgaacga tatattaata attggcagta agttatatca aataagatat tactatagag
     4921 taatgaatta tattgaacga tatattaata attggcagta aattatatta aataagatat
     4981 tactatagag taatgaatta tattggacga tatatcaata gttggtagta agttatatta
     5041 agcaagatat tactatcagg tagtgaatta tattgaacga tatatcaata attggtagta
     5101 aattatatta agtaagatat tactatcagg tagtgaatta tattgaacga tatattaata
     5161 attggcagta aattatatta aataagatat taatatcgag taatgaatta tattgaacga
     5221 tatatcaata attggcagta agttatatca aataagatat tactatcgag taatgaatta
     5281 tattgaacaa tatattaata attggcagta agttatatca aataagatat tgctattatg
     5341 tagtaaatta tataaaacaa tgtatcagaa taaatagtat attaataatt tgtagtatat
     5401 catgacgaat aatacagtca taacaaatag tgagtcataa caaataatgt atttataatt
     5461 gataatgtat ttaaaaatca aaatataaaa acttataagg aaagagagat taatttatat
     5521 gggtaaatca aaagatgttg aaatagagaa gtctatttta ggcacaattc ttttagacaa
     5581 taaattaagc tataagctag atgaattaaa tgaaaacatg tttatgaatg atatatgtct
     5641 tgagatattt aaaattatga aagaacttaa aaaagaaaac atagtgattg atgtggccac
     5701 tgtgaaatca aagatagata gaaaatctct agcaataaaa acaagtgatg tgactaatct
     5761 aattacttgg ggtcagaatt ttggtcttga tggtcatatt aaaattttaa aagaaaattt
     5821 agctagaaga agcataaatc aaaactgcca aaacctttta cacagcctaa accttggaga
     5881 aaatatcgat acttgtattt acaaatttga aagtaatata aaggagattt tggacaagga
     5941 tacttatgaa aatgatgatg taaatagtat agcagggaag gtgcttgatt ttttagaaaa
     6001 caaaaaagat attggattta aatttggtat aaaattactt gataccacta taggaggtct
     6061 ttttaaagga gagctaacca caatagcagc taaatcgggg gttgggaaga ctgctttggc
     6121 acttcaaata atgttaaatt catttaagca aggtaaaaaa actttattta taagtagaga
     6181 aatgaccagt gagcaagtat ttatgagaaa tatatgcaga gtaactggtg taagtacaag
     6241 gaatatgaaa tctaaagaaa tagatgaaaa tgattggaaa cttattgtaa atgcgatagg
     6301 tgatttaagc gaaaataact taatttatat caatgataag atagatacaa ttagtgcaat
     6361 tagaaagagg ataaggcagg taaagccaga tttattaata gtggattatg tgcaactcct
     6421 tacatctcag aaaagcatgg ataagagaga aagggaggta gctacttttt cgagagaact
     6481 taaaaatatg actttagatt ttaatatacc tgtaatccaa ttaagtcagt taaatgatga
     6541 aatgaaagat tcaagacctt atggagatag acctatgagg gatagcaaag ccatctacca
     6601 cgatagcaac aatgtggttt atatacatca attaaagggg agtgattatg aagaagcagt
     6661 gagagatatt ggagaaagtg aggaggcagt tagagcatca gaatacaggg gaattaagat
     6721 ggttgattta atagttgcga agtgtagaga tggacagact aggcataagc atttttgtta
     6781 ctttggggat aagttacatt ttcaagaact aaattattag gtcaataaag tagtaataac
     6841 aagcttatta aaagtcggga aatagcaaat agattataaa atatgaggtg aaaatatgtt
     6901 ggaattaaga aaaattatag aattacttga agaacacaag atagaagtaa gtattccaaa
     6961 ggagttacat aagtatagtt tattggaata ccttgaattg tgtcaacaaa gtgggggaac
     7021 atatttttat attaaaacac tggaaggggc tttaaaagag gctagaaatg agcttatgat
     7081 taaattgttt aatgggaaaa attatatgga attagcgagg atgtttgaaa tgagtgttat
     7141 taatgtcagg catattgtta gaaaaaaata gatatttttg gagaatacaa gtgtgatata
     7201 cttctgaaat agaagttatt ataagaggag tataagtgtg attaacaaca tgattttgtg
     7261 aataaaattg aggatatata tgagttaaat gtgtgattaa taaggtaaga ttgtgtataa
     7321 gattatgagt atttaaaagg aggggctata attaatagtg tagagttgtg tgtttgctta
     7381 agattatata ataatttaat agattaaact atactaataa ggtaaaatcg tgtgtttagt
     7441 taaagcttat tataaaatct tgatatgtga ttaatgatgc aatatgtgaa taaagttaag
     7501 attataatag atttaacctg tggctaatag aataaaattg tgaataaagt taagattata
     7561 ataggtttaa attgtgacta atagagtaag agtgtaaata gagataaact tcaatatgag
     7621 cttaacctat gattaataga gtaagaatgt aaatagagat aaacttcaat atgagtttaa
     7681 cttgtggcta atagagtaag agtgtaaata gagataaact tcaatatggg tttaacttgt
     7741 ggttaataga gtaaggtgta actaaagata aacttcaata tgagcttaac ctatgattaa
     7801 tagagtaaga atgtaaatag agataaactt caatatgagt ttaacttgtg gctaatagag
     7861 taagagtgta actaaagata aacttcaata tgggtttaac ttgtggttaa tagagtaaga
     7921 atgtaaatag agataaactt caatatgagc ttaacttgtg attaatagag taagagtgta
     7981 aatagagata aacttcaata tgggattaac ttgtgattaa tagagtaaga gtgtaactaa
     8041 agataaactt caatatgagc ttaacctatg attaatagag taagaatgta aatagagata
     8101 aacttcaata tgggtttaac ctgtggttaa tagagtaggg tgtaactaaa gataaacttc
     8161 aatatgagtt taacttgtgg ctaatagaat aagattgtga ataaagttat agttttagat
     8221 gggtattaac ctgttactaa tagaatatga ttaggtgtaa aattatagag ctgcataaga
     8281 aaatattata gatatattaa atattagata ataaatattt atatagatac acaaaagaaa
     8341 aggcgatatg aagctaaact taatgacttc atatcgtttt ttatttgaaa ctcctttgta
     8401 tttagagtgt gatttttaat attgaggttt tatgtgatta agtcacagat aaaaagtaag
     8461 tatcttgata taattcttat agattaataa tatagggagg ttattatgtc taataaaaaa
     8521 aagaagtatg caaatatttt agcaaatgag tgcgttgctt gtggtagctg tataaaagca
     8581 tgtccaagaa gtgctatctc agttccatgt ggcattagtg caaaaattaa tagagattta
     8641 tgtgttggat gtgggatttg tgaaaagata tgtccagcat ctgtaattga gattataaca
     8701 atattaaaag aggaagaagg taagtgtcat gaataataaa aaacattggt atgactattt
     8761 atggattttt tcttcaatat atttgatatt gggatttgta aatattattt tcgcttggat
     8821 tgggctaatt tgtttctttg ttccactagc tatttctatt gttaagggaa ataaagctta
     8881 ctgtaataag tattgtggaa gagggcaact gtttaatttg cttggaaata aattgaagct
     8941 gtcaagaaat agagatattc ctaaatttat tagaagtaag tggtttagat atgggttttt
     9001 gacatttttt atggtaatgt ttgccaatat gcttttttca acttatttag tgtttgaagg
     9061 aagtagaaat tttaaagaag tagtgacttt gttgtggact ataaaaatgc cttggcaatg
     9121 ggcgtatcat ggaactttag tttcaccttg ggtggtacag tttgcatttg gtttttatag
     9181 tgttatgctt acatcaactg ttcttggttt gattactatg atattgttta aacctcgttc
     9241 atggtgtgtt tattgcccta tgggtactat gactcagatg atatgtaagg caaagagtaa
     9301 gtctgtatag aaaggcctta tgtgatattt acagttttgt tcaagtagag atgagtagta
     9361 ggtttgaata tatatgacaa atatatgagt ataggggcat agatttagtt tgtgtaaggt
     9421 aaactgattt atgcttcttt tttatgtctt agattattgg ctaagtggaa acaatgaatt
     9481 tagatattaa gaattattca gttatttgaa gaaaatagaa taataattaa cattatatta
     9541 atggatattc attacatata agccagttaa tagcaagatt tatttaatat gatataggtc
     9601 aagtatttaa actaaataag gtcatgacaa ttaatataag tatagatata aaaagattag
     9661 aagttataac ttataaaagg tattctatat aaatagtatg gggaaaatag tcaaattaac
     9721 ttattagaaa caaaaaatat acataaaaaa taaatgtaaa tatcaaataa gatactatat
     9781 caaaatagat ataagtatct tttttattat tgaaattatg aaaatatatt tgattttaca
     9841 caaaaaagag tgcctcatga actaaaaagt tcattttgag acacactttt acagtgtcaa
     9901 agaacgaagt ttatccttat ccaatacctt tataccacca cgagataaag acacaatacc
     9961 ttctctagca aaatatttca acattctcga tacaacttct ctggcactac ccatatactt
    10021 agcaatttgc tcatgagtca tatttatagt gctactgcca tttttagcta tctcatcaat
    10081 taaaaaagat gccaaacgct tatcaaaact cataaaaaga atttgttgca tagcccacat
    10141 aacatcagaa aaacgttcag tagctaattt atatgaaaat aactctgcat gaatattttc
    10201 tgtagataat tttgcaaaaa cagaggaact aatctgtata atatcgcagt ccgtttcagc
    10261 atctacatag acatcaaaag ttattgtttt tagaatacag gaagctgata aaatacatac
    10321 atctccatca tcaagtcgga acagtgtaac ctctcgacct tcatctgaaa gtatgtatgt
    10381 acgcactgtt ccagatttta taatcaaaat accaatacag tcactatcac cacaatgtac
    10441 tggattccct tttttgtaat gcgaggtatt tgctgaagaa attaataatt ctttttgtaa
    10501 gtcagtaagt ttatcccaaa aaggcaagct atgtgtaagt atatcaattt cattttgtga
    10561 aatcatacaa tatctccttt cttaaattgt tataatccca tgatacaagt gaatagataa
    10621 attgacaagt agtttgttaa gaggattatt tagtcagata gtaatagtat gatttatgta
    10681 gaaaaaatat gataatatat attcttgcta ttaatgagaa agtaatatgt tttgatgata
    10741 gtaggtttgt ataactaatg cataccgttt atttttaaaa gattaagttc cttatgtaac
    10801 cttatagaca taaaaccagc aattatagca gccatcaaat cagctattgg ttgtgcatat
    10861 aagataccat ttaacccata gaatacagga ataatcaaaa ttatagggat aaaacagaca
    10921 ccttgtctac acatacctaa aaatccacct tcctttgctt ttcctagtgc gaggaataat
    10981 gtagaataca ctgtatagaa tccaaatagc ataaatgaaa acccatttgc cctaagagct
    11041 ttactaccat tttctattaa taaaatgtca ccacttgtaa attgtgaaat tatagatttt
    11101 gggaagagta tcaatataag accaagcact acacaaaata ctgtagtcca taatatggaa
    11161 gtttttattg ctatatgtaa tctatcgtag ttctttgaac caaaattata accagcaatt
    11221 ggttggaaac cttttataaa accaaataca acaagactac ctaaagacgt tattcgtgtt
    11281 acagcaccca ttccagctat cacagaatca ccatactttg tagcctccat attagttaat
    11341 gtaatagcaa gactagtcaa taattgaaat attaaggtag gtatgccaat ttttaggatt
    11401 tctgaaaaaa tttcttttga aaaacagcat tcgttaattc taaaactaaa tatacttttc
    11461 ttgcttaaaa tatatcctac ataaacaagt gttgaagcaa tctgtgagat agctgttgca
    11521 atagaagcac cccttacccc cagaccaaaa gtataaatga atatcgggtc taaaatcata
    11581 ttaagcaaag cacctaataa catagcacac atagttgttt tagcagctcc ttcacttgtg
    11641 acaatattag tcatagtgac attgaatata ttaaaaatag atgacacgac ataaatgcta
    11701 gcataagata ttgcataagg cataatactt tttgtagctc ctaacaattt taaaattgga
    11761 ttgagaaaaa tcataatcac aataataact aatgtaccca ctataatact actgtaaata
    11821 gatgtactta ccacttttcc tgctttttca ttatcaccat ggcctaaaag tctggcaaca
    11881 tatgaagcag ctccatttcc aaacaataat cctaatccca caacaagctg acctaatgga
    11941 aatgcaacgg atatagctcc catttgactt gttccaagtc cacccacaaa gtatgcatca
    12001 accaaattgt ataatgcagt tatcatcata cctatcatgg taggtaatcc catagataac
    12061 aatgcttttg agattggggc agaccctaat aattcaattc ttttgttact ttctttcata
    12121 cttaacactc ctcttctatt gacattaagt ctaaattata atactataaa ttatagtaag
    12181 tatggaaaat agtactataa tttatagtat ttgtcaatag taagaaaact aaaggagatg
    12241 atttttatgg ctacaataga tttaattgta ttgggaatag taaagcaaca acccaagagt
    12301 gcttatgata ttcaaaaggc agtggaatac aggaatatat cacgttgggt taaaataagt
    12361 acaccatcaa tttataaaaa agtaattcaa ttagaacaaa agggatatat tgaaagtaaa
    12421 actgtgaaga atggaaaaat gccagaaaaa gcagtttatt cattaactga attaggtgag
    12481 acacattttt tagatttaat gtttgataca tctagcaaac caataaatat tcttttagat
    12541 tttaatgctg ttatagtaaa tttaaatagc cttacaccag aaaaacagaa attatgtctc
    12601 aataatattg aagagaatgt tcaagagtta aagaaaacta ttgaggaaaa tataagtata
    12661 aagacagaag taccagacac agcaaaagca gtgttggagc aacagttggt gctagcacaa
    12721 gcattggaaa cctggataaa ttctttaaaa gataatatgg gaaattagaa ttagagaagc
    12781 taacttaata atcattaaac aaaaaccagc atatttaata atgagatatt agaaaaaata
    12841 aaacaaatga tataaactga aaagtatatt taaaataaag ctcacttaat tgagggagaa
    12901 tgttaaactt tt
//
LOCUS       DAEHWO010000103        12885 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEHWO010000103 DAEHWO010000000
VERSION     DAEHWO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12885
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.105"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            113..301
                     /locus_tag="KNP54_003491"
     CDS             113..301
                     /locus_tag="KNP54_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBF0894351.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(461..613)
                     /locus_tag="KNP54_003492"
     CDS             complement(461..613)
                     /locus_tag="KNP54_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBF0894352.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(711..1187)
                     /locus_tag="KNP54_003493"
     CDS             complement(711..1187)
                     /locus_tag="KNP54_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBF0894353.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1406..2167
                     /locus_tag="KNP54_003494"
     CDS             1406..2167
                     /locus_tag="KNP54_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0894354.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLCYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2427..4355)
                     /locus_tag="KNP54_003495"
     CDS             complement(2427..4355)
                     /locus_tag="KNP54_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBF0894355.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSENSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4589..5041
                     /locus_tag="KNP54_003496"
     CDS             4589..5041
                     /locus_tag="KNP54_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0894356.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5044..5352
                     /locus_tag="KNP54_003497"
     CDS             5044..5352
                     /locus_tag="KNP54_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBF0894357.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5466..6572
                     /locus_tag="KNP54_003498"
     CDS             5466..6572
                     /locus_tag="KNP54_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBF0894358.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6647..9325
                     /gene="mngB"
                     /locus_tag="KNP54_003499"
     CDS             6647..9325
                     /gene="mngB"
                     /locus_tag="KNP54_003499"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBF0894359.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDKYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIVKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9642..11975)
                     /locus_tag="KNP54_003500"
     CDS             complement(9642..11975)
                     /locus_tag="KNP54_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBF0894360.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11950..12666)
                     /locus_tag="KNP54_003501"
     CDS             complement(11950..12666)
                     /locus_tag="KNP54_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894361.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         4802 a         1795 c         1672 g         4616 t
ORIGIN      
        1 ttcaatatgt gtaaggcaaa tatatatttc tattgcaaat ttttgttatt tatgataata
       61 taaatatgtt tttagtcttt aaatagttat cattttaagg aggtgtgcgt agatggcaaa
      121 agtatgtagc gtatgtggta aaggtaaggt ttctggaaac caagtatcac actcaaataa
      181 acataataaa agaacatggt cagctaactt aagaagcgta agagcgatta tagatggagc
      241 tcctaagaga gtaaaagttt gtactagatg tttacgttct ggtaaaattg aaagagctta
      301 gtaaccacgt ttaaaagcct acttccgtaa gtaggctttt taatttaatc atttttactc
      361 tttctcataa attttaggat tatacttgaa atccattttg gtaattttat tgttactact
      421 ttcatcaata ctcaccccac actttatagt taaaactatt ttaacaaaaa aataataatg
      481 ctccacatcc aataagtatt aatgcggtaa gtgctgacca aatccagcca ggaagcaaca
      541 ttgacagaat tacagccatt cctgttgcta gacaaagtat tcctagcaat accttagact
      601 tgttatttct catggaacac ctccacatag aacctgtatc tataaatatt ttcatattca
      661 agtttatgcg acagttttcc attttagacc aataaacaca ttatgtaatt ttaatttttc
      721 atactagaat tattactgaa ctccgatata gattctacaa tatccaaaat tccttttttt
      781 ctacttaacc tttcaggtcc actatataaa acaactggta taactttagg aagtttaaaa
      841 tttttatctt ctatttcttc aaggcttttt ttcataataa aacttttcca aatttgttct
      901 ctatacgatt tcaatcttgg gacaatttca gtatccattt ctgtttgaaa ttctaacact
      961 atataatgtg atactttgcc gcttttagaa aataccttat aaattatatc aacttctttt
     1021 cctttatatt cacatataaa agatgtttct aactctatat ttttaagagt taattctttt
     1081 gctattgaga cacttgtaaa attttgaatc aaacttaaaa aactttcttt atctgaatac
     1141 attcttctgt actcttctcg tttttcattg cttcttttta aattcataca gttcctccta
     1201 gactatagac cttctatttt ttagtaaaga tagtctataa attttatttt ttaattttca
     1261 ctagtgagta ttgacagttg tgtgtaaaat atccagtaaa gatatttttt tatattttta
     1321 ttaaaagata taaattttta tattttaatg tattgacatt tacgttgcgt aaaagtgtat
     1381 atttaattta taggaggtac tacttatgga atatacagtt caaaaattaa gtaaactagc
     1441 tggtataagt actagaacac ttagatatta tgatgaaata ggtcttctta agccacttaa
     1501 aataaattct tcaggttatc gtatatatgg tcaaaatgaa gttaataaac ttcaacaaat
     1561 acttttttat agagaattag gaattaactt agaaaatata aaaaacatta taaattcacc
     1621 aaacttcgat agtttaagtg cgttaaaaga acaccataat aaattactag ccaaaagaaa
     1681 gcaaattgat ttactaatag aaaatgtaac taaaactata gctctgaagg agggaaaata
     1741 cactatgaca gatatagaaa aatttgaagg ttttaaagaa aagatgattg atgaaaatga
     1801 aaaaaattat ggaactgaaa ttagagagaa atatggtaaa gatattatag atacatcaaa
     1861 taaaaaactt aaaaatatgt ctaagcaaga ttatgaaaat tggcaaaacc taaatatcga
     1921 aataattagt aaacttaaaa aagcttttaa aactggtgat gcctctagtg aactggctca
     1981 ggaagttgca aaattacatc ataaatggtt gtgttacact tggaacacat actctaaaga
     2041 agctcattcc tctctagcac agatgtatgt atatgatgaa cgttttacat catattatga
     2101 tagagaacaa cctggattag ctaagttttt aagggatgct atagtaatat atacaagaga
     2161 taaataatat aaaataataa aggtggtgtc tcaaaatgaa ctttttagtt catgagacac
     2221 tcttttttgt atgaaatcag atatattttt atcattttat caatgaaaaa caggtttctc
     2281 tctctatttt gagacagaat ctttattgta taataattat aatcaataca aaataataac
     2341 aaattataca aaacttactt atactattta tgctaaaaac aaaaaatatt ttattaaagt
     2401 ttttaaaact tatgtaatat aaaaatctat actatagact tgattatgga aagaaaatta
     2461 tcaaaatcat tacaattaga tatactatct ctaatatcat tgtcatgaat tatctttaaa
     2521 aggatatcat aaatggagtt tatttttata taatcatctt tatttatagc caacatcatg
     2581 attaatttaa cagtagaatt ttcactccaa tatattggtt cattcaatat ggaaatacaa
     2641 atcttagttc ttatagagct taattccata ggatgaggta tagctaaaaa atcatctata
     2701 ttggtagaag ataaactttc tctgtaaaat acagattcag caaatgatgg aaatacaatt
     2761 tcactttgag ttaatttgtt gcacatcaac tttataagct catctttatc tttgatttta
     2821 ggattaacaa taaataaatt tttatcaaag aaattgtcca aaagattact ataaatatgg
     2881 gaattattag tgattgactt agatatattc tctatatctt tttttaatag ttttaaatcc
     2941 actaatacaa taggaatact atcatgattt aaaggaattg tcgatattat tatatctaca
     3001 tctgacaatt cactagctaa aaattgatta aatgatagac attgaagtat atttatttta
     3061 tcatgaaaaa ctttgtttaa ttgaacctct aataacctac ttgaaccata ccctgaacca
     3121 catactaata ctacgttttt acacttaata ttactttgaa aaaatctctc tattccagca
     3181 cctatatgca gggatacata tccaatttca tcttctgtta aagagtaaat actattttta
     3241 aaaacttttt ctatagcatt taaagttatt tcaaatgcta aaggataatt actctttatt
     3301 gtatttataa ggggattcac cttatttaaa ttataagatt tagaattgag aattgattta
     3361 aagtgcagta ctaaatcatc aaataataca ctatcatttc taaggtcaaa agtatattga
     3421 ttgttgatta cttctaaaat ttcttcaaca tactctataa ttttagtatc taccctattg
     3481 gaaacgttat ccaaaagaga acttttagtt ataaaatgat tatatagata aactctgtct
     3541 gcctttgaaa taattatagt atatttactc tcaatataat taaatatatt ttcaacagtt
     3601 gtattcgatt gaaaatctgt taaaacaaca tctaaaacat tatctaagca gtaaccatca
     3661 agtattctac ttacagtaat agctaaatgg ataataaagt tttttagatt aaaatctagg
     3721 aaattgatat taaatttatt aatttcactt aacactaccc tttgaagctc tattaaatct
     3781 acattattaa ataattctat ttctctatct gtaattccaa ttatatagtt ttcaaaattc
     3841 ctatttatca tattattaga aatacatctt cgaatatcta tttccttacc ttcaacttta
     3901 actccataat atggcttaga aactaatatt aaattatact ttgacaaaat aggctttatt
     3961 ctttttatgt catttagtat tgtaaattta ctcacataca agctattagc taaatcttct
     4021 agttttatat atgtattgtt atagagaata tattttaaaa tatattgatt tctttctata
     4081 ggagaatctg gtatttcact tgaatccata atatcatcag atattaatgc tagatactgt
     4141 tggtataatg ctaaattaag aatatctata taatatcctt ctcctttttt tattttaata
     4201 atagcaccat ttttctctaa agttccattt atagaagtaa tatcatttct tatagttctc
     4261 tcactcactt ttaaatgatt acttaaagtt ttacaagtaa ttttatcatc actttcattt
     4321 aataatttaa acaacgtgag caatctcttg tgcataaata tcccccctta tagaatttct
     4381 tctaaattat actatttaca ctcatataat acaattactc taataaaatt gtattataat
     4441 aatttatttc cacttctata tggaaattag ttattatcat aatataaatt tccatgtcga
     4501 agtggaaatt agttatattt aatttaatta ggataatgat tacaatataa atataagtta
     4561 agacattatg aatggagtgg aaaaatatat ggtactacaa gaaaaatata tatttataga
     4621 taaagactta aaaagcaaag aagaagtatt aaattttatt gcagatagtg cttatatact
     4681 aggtattaca actaataaag aggctctttt aaaagacctt ctaaaaagag aaaatgaatt
     4741 tccaacagga ataaaagatg gatttgcgat acctcataca aagagtgtaa atgtaaagga
     4801 agcttccata ctctatatta aaacaactaa cgagttagaa tggaaaactt tagatgatag
     4861 taaggttaga tatgtattta gtttgttagc cccacataaa aatgaaggaa atatacattt
     4921 gaaaactcta tctaaattag ccacatgttt aatggaggat gattttacaa gtgaagttaa
     4981 aaatgctagt gatgcaagtc atttagtaaa atatataact aataaaatga aggaggaata
     5041 attatgaaaa tagtagctat aacatcatgt atagcaggat tagcacacac acctatggca
     5101 gcaaaagctt tagaacaagc tgcatcaaaa atgggtcatg aaatcaaagt agaacaacaa
     5161 ggtgctatgg gacgagtaaa tactataaca aaagaagaag cacaagatgc ggactttata
     5221 cttatagcat ctgaccaaac tatatctgga atggaaagat ttgatggtaa aaaagtgata
     5281 aaagtcaaaa taggtatagc gttaaaaaaa ccagaagctg tcttaacaaa gtgtatagaa
     5341 gctatttctt aataaaaaaa tctcactcta atatagaatg agaaaaatca aaaattaaaa
     5401 aattgtctaa tgtaattata acatattatc aaaaaatata acaaacttat ataggaggat
     5461 taaaaatgag taaaaaaaat aaatctcttt taagtgaact taagggacac ttaatgacag
     5521 gtatctcata tatgttgcca cttgtaatag gctcatcttt agttgtagct atcccaaagc
     5581 ttacagcttt agcagtgggt ataacaagtt tagatgctta taaaaatgta tctggttttt
     5641 atcatattct ttacttaatg gaacaagttg gttggactgg cataggtcta ttaaatacgg
     5701 tattagcagg atttatagca ttttcaatag gtgagaaacc agctatgggt gcaggtttta
     5761 ttggtgggct catagcaagt aatactaatg caggattctt aggagcagta atagcaggtt
     5821 tctttgctgg gtatgtttgt aagtttttaa agaaaaaaat taaaatatct gggtcagcat
     5881 caggaatgat gccacttata ataatgccac ttataacagt tggattaact ggttttttaa
     5941 tgagtgttgt attagcagga cctttaggaa acataaatac ttcattaaat gcttgggtag
     6001 ctgaaatgtg tcaaaatgga acaaattcgg tggtattggc tttaatttta ggcgcaatga
     6061 taggattcga tttaggtgga ccagtaaata aagcagcttg gatggcagga aatgcattat
     6121 tgttagaggg aatctatcta ccagcgatat tggtaaactg cgcaatagtt atacctccac
     6181 taggatatgg tttagctaca ttcataagaa aatcaaaatt ttccaatgca ttagctgaaa
     6241 caggaaaagg caatatagtt atgggtataa ttggaataac agaaggtgca attcctttca
     6301 ctttaacaaa tccattaaaa ttagttcctg ttaatatgat aggatgcgct ttgggtgtag
     6361 gattatcagc tttgttaggt gtacatgcta taatgcctcc agttggtgga ttatatggat
     6421 ttatatcaat aggttctgga tgggcttact tagtaggtgc aatatttgga gctttagtaa
     6481 tagcaatatt atcaacaact ttagtagact tcaatgaaga tgaaactacg gaaaatacag
     6541 aatttgatga aatagagtta gatataatgt aaattaaaaa cttaatttta gataattgag
     6601 aattgagtgt actctcaatt ctcaattaaa ttttgggagg atttttatga aaaagacaaa
     6661 agtacatgta gttccacaca gtcattggga tagagaatgg tattttacaa catcaaggtc
     6721 aaaaatatat ttaatgaaag attttcaaga tatattagac atattggaag aaaaagaaga
     6781 ctttaaatac tttactatgg atgcacaagc ttctctctta gatgattatt taaaatggag
     6841 acctcaggat aaatatagaa taagagattt agttcaaaga agaagattag ttattggacc
     6901 ttggtatact caaacagacc aattggttat atcaggagaa tctataatta gaaaccttta
     6961 ctatggaata gatagatgca atgaatttgg tgaacctatg agggttggat atgtaccaga
     7021 ttcttttggg caatcagctc aaatgccaca aatatacaga ggttttggaa tagatagttc
     7081 attattttgg cgtggagttt ctgatgatat ggtagataca acagagttta tatggaaagg
     7141 ttctgatggt tcaaaagtat tagcagttca aataccattt ggttattact atggaggtaa
     7201 tataccagaa gatgattcag atttaaaaga atatttaaaa gatataatcg taaaacttaa
     7261 ggttaaagct tctactaata acgtatattt tccaaatgga tttgaccaag caccaataag
     7321 aaaaaacctt cctgatatat taaaaaaagc taatgaaata gataatgaaa atgaatacga
     7381 aataagtgat atagaaaact atatagattc agtaagaaat gaaagaaatg aatttacaga
     7441 gcttaaaggt gaatttttaa atgctaaaca tatgagaata cacaaatcca tattctcctc
     7501 aaggtcagac cttaaaataa tgaataacaa attagaaaat tatattacaa atgtacttga
     7561 accgttatta acattaagtt attcacttgg aaatgaatac cctcacctag ttataaaaga
     7621 tatatggaaa cttatgtttg aaaatgcagc tcatgacagc ataggttctt gtaatagtga
     7681 cacaacaaat gaggatgtat acacaagata caaacaagcc agagatttga gtataaattt
     7741 attagatttg catatgagac ttataagtac tcaaatcaaa aataataatg aagaaataac
     7801 attaacagta ttcaatggat tcccagaagt cagaaatgaa gttgtagaat ttgatactta
     7861 tattccaggt caagattttg tgataaagaa taaaaatgga aaaattctta attatataat
     7921 aaaagaaaaa gaagatatta caaattatat attaactcaa acaataagat taaacccaag
     7981 taaaaaaata tatataccca aaactgtata tagagcaaaa attgcacttt cagtaaaaga
     8041 tataccacca atgggatata ctcaactagt ttttgaattg gatactaaaa ataaatgtga
     8101 aatagaaaca agtaattgca aggaaataga aaacaaatac tacaaaataa cagccaataa
     8161 aaatggttca ttagaaatat tagataaaga atctaataag acttataaaa accaagctgt
     8221 aattgaagac aatggagatg atggagattc atacaactat tctcctccaa gaaaagatat
     8281 ttatgtttca tctttagatt ctgtatcttc agtagaagtg ctaaaatcaa acattcaaga
     8341 agaaatgata cttaaatatt cattgaccat accagcttca ctggaagaaa gggctatagg
     8401 taaagtttct gtgaaaatgc cagtaacaat gaaaatcacc ttagaaccta aagaacaaat
     8461 aattaagttt aatgttaata taaaaaataa ccaagcacta tctcatagag taagagtttt
     8521 atttaataca gaaatagcat ctaagttttc tatagcagat caacaatttg gaataataca
     8581 aagaccaaca gtattagaaa aagaccttgc attgtggaaa agagacaatt actcatggca
     8641 agaaaaacct ataactatcg aaccaatgca aagttttgtt actttagagg atggacaaag
     8701 aggaatagca ttaataactg gttgtgtaag agaatatcaa atagttggtg ataatttaga
     8761 tacaatagca ttaacactat tcaggtcatt tggatatatg ggaagagaaa atttacttta
     8821 tagaccagga agagcttctg gagaaaaaat aatagcaaca ccagatgcac aattacttaa
     8881 agagttaaac tttgactttg gtctttacat atataacaat aaatttgatg aagcaaatgt
     8941 agctaataca gctaagagat tcttaacacc tatacaaata tatgaatatg ctgatttttt
     9001 aaatggtaga cttatatttg cattcaatga cgaaaaacaa atatatgaaa atgaatttag
     9061 tttgatgaat gtaaataatt caaatttcac agtaagtgca ataaagaaag aagaaaaagg
     9121 agatggaatt gtagttagaa tcttcaatgg tatgaaaaat gaggatgcta agggaagtct
     9181 taacatcaat aaaaatgtca atgatgctta tagtgcaatg ctcgacgaaa tctatgataa
     9241 tactagcaag cttaaagtaa atactaaaac tgtagaggta aattctttat cacattgtaa
     9301 agtacaaaca atagtaatta aataatataa aatagcttat acaagatttc aaaataaatt
     9361 gctagtacca tgttaatagt aaagccagat attatgctat ttataagctc tgtaacacta
     9421 aataacattt tgtaaaataa aaaggtgaac cttgtatatt aggattcacc ttttttaaat
     9481 aaatcaacat tctgttttaa aataacattt ataagctgtt ttgaaataat gcttacaaat
     9541 tattttaaaa caatacctat aaatttttat ttaaagaata cacataaata tttccagact
     9601 cttttatcct atagacttta taattattaa agaagtctaa tctaattttt gttaaaagta
     9661 attgtaactt taaataaatc accatccaca cttatattca tcttaccacc ctgtaattct
     9721 ataaaacttt ttgctatcgc taaaccaaga ccagaacctt ctgtgttacg tgatttatct
     9781 cctcttacaa atctctccat tatatcatct acactaaaat caatctcaga tgcagacata
     9841 tttttaagca taatatttac tttattatct gtttctaaaa tatcaatata cactcttgaa
     9901 tttggcattg catatttgct tatatttatt ataagatttt caaatactct aaatgtacgc
     9961 tgactatcta atggtaatat tattttttca ttagaaaagt tattctttac tattagagat
    10021 gaatctgcaa gtttgtcatc taattctaaa agtgtctgct tcattagaga tacaatatcc
    10081 acatttacta tattcaaata aacatctcca ctatttgcct tgcttacttc aaacaaatct
    10141 tctattagat gttgcaatct ttgtgacttt ctgtctaatg tatcaatata caacttacga
    10201 ttttcatctg ttatactttc atcttttaat aaatctatat aagtgattat agatgttaga
    10261 ggtgttttta agtcatgtga tacatttgat ataagctctg ttttcatctt ttgactctta
    10321 acctcttcgt caacagcttt tttaaatcca gtttgaatat ttcctaattc gtcttttata
    10381 ggattaaaaa atcctaaatc tttttccata tttacatcta agtttccatc tgaaattttc
    10441 tttgtaacat ctaaaagttg attatattca tatattgtct ttttagagta atctgacagt
    10501 attttaaata atactactga atatattaat gcgagtatta ttccaaagaa ccacatacta
    10561 cacattataa ctataatcaa taaatttatt cccaaaattg taactatagt tttatttggc
    10621 ttttctttta gatttattgt tctaatttga ttaataactg tttttcctgc tttttttagc
    10681 catacaaaaa acattcctgt cacagtatgt tttgtaaaat actctcttat tccaacattt
    10741 aaaatatgtt ttaaaagtat tataaataca aatattattg agaatattac aaaccaataa
    10801 gttaaattca ttaaacttac caatatacta gccattttag cacttatgtc attgtttata
    10861 aggtactcta cataattccc actcaaggta ttacttatta taacagtagg atataaatct
    10921 acaagcccct gtataatagc aagagcaata aagagtatct ctaacggtat tcttgataat
    10981 gtatcaaatc ctagcaactc tttagatttt ctatatggga atgctaaagc tacaataaca
    11041 actatagcta atataatttt taaaatcatt ccagaaatct tataataaga attattttct
    11101 acattgctta tatatgaaat tataccatca tcaaaataag tatttccata accatactct
    11161 acactatcac ctttacttat tactttaggt acagcatata ctaatgttat attttttatt
    11221 ggagataact tatatgaaat tgaatttcct cctaaacttg tatccattaa atcttctctt
    11281 gctttagata acaacatttg attaataatt ttttgattta ctccataaga atccacaata
    11341 tttacttttc catctttatc aaaattcatt acaacgtaga atctatagtt ttcttttata
    11401 tctgtaatct gcttttgtct ttcctcatca ttcatttctg tattttttga ctgattttca
    11461 tcagaatttt cttttgaagc atcatttttt gttgtatcaa gtactcctaa ttctttatta
    11521 tcattaaaaa attcaaaatt gctttcttta tcaactaaat agtactttaa attctttcct
    11581 gacgctttaa tgaaatgctc ccaattttca aagttttcat taaaatctgc attaatacta
    11641 tcatctgtat agtaagtttc tgaaccatca taagtatctt tttctttact tacatttttt
    11701 atatagttca tagtttcttc attgataaat agttttgatg gttgtatcat cttaccttct
    11761 tgttcttcct tcatattatg atataaaaca taacttcctt tatatatact atctacaaag
    11821 ctttcctgtt caaatggatt ctctgctcca cctttagcac ttgcttgtat agtagaatat
    11881 tgactaatca tacctaatga tgctgataac ataagtataa aaactataat agtaactata
    11941 tatttatctt taaatttttt caattttgta tccaacaccc cacaccacct ttaaatattt
    12001 aggatttttt gggtcaattt ctatcttttc ccttatattc ctcacatgta ccataactgt
    12061 atctgtattt acagcattct cattccaaac tctttcatat atttcatcag cagaaaaaac
    12121 tcttcctgca tttctcataa gtaaacttag tattttaaat tctataggag ttgtttttat
    12181 atactttcca tcaatactaa cttcttttgt attttcattt aattctaatc cgcctattgc
    12241 aaacacacta tcgtcacttt ctaccttttg ctctttattt ccaaccatgt ttagatactt
    12301 agtgtacctt ctaagttgtg aattaactct agccaatagt tctaatggct taaaaggttt
    12361 tgttacataa tcgtctgctc ctatattaag ccccattatt ttgtcaactt cctctgattt
    12421 tgcagatagc attattactg gaaaattata gttttctcta agcttcattg taagtgttat
    12481 accatccatt ttaggcatca ttatatcaac tatagctaaa tgtatttctt ggttttctat
    12541 aaccttaaga ccttctaatc cattgtatcc cttaaaaaca ttatatcctt gatttaatag
    12601 atatatttct atagcatctg ctatctcctt ttcatcttct accaccaaaa tattatatga
    12661 attcattcta atctccttta tattaattta taaattttct ttacatatat gattatacaa
    12721 tatgatagaa gtttttccat ttatatatat atttatatct tttgttctgg ttatttgtat
    12781 ttaatgtcca tcttagaaac ctccttctag tttaaattta atattttttc attttgtttt
    12841 atatacttaa tattaaaatt aaaaacttaa gatattacat atact
//
LOCUS       DAEHWO010000104        12250 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEHWO010000104 DAEHWO010000000
VERSION     DAEHWO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12250
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.106"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            170..865
                     /gene="cas6"
                     /locus_tag="KNP54_003502"
     CDS             170..865
                     /gene="cas6"
                     /locus_tag="KNP54_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBF0894362.1"
                     /translation="MIKCLEMSVKVYLLENISLDNTSKEIRKLIDDTLIIEEKYKEFH
                     NKAGFKNYSFNLLYPLEKDKVYKKDCIYTFIIRTVDSELGMYFMNNLKNQHSDKIKVI
                     TMSKKVIPKKHIESIYSVTPIIAKFEDGYWRSNKTVEDLEKRIRENLIKKYNEFTNSK
                     IDEDFELFQVIKFINRKPISTKYKNISLLGDKISFKVSENDMAQEIANFALGVGVGEI
                     NSRGFGFVNYRWL"
     gene            856..2616
                     /locus_tag="KNP54_003503"
     CDS             856..2616
                     /locus_tag="KNP54_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cse4"
                     /protein_id="HBF0894363.1"
                     /translation="MVIGGENLLKDCLEIFEKEYKSLGNRLITDSYVLSYGTYILVKN
                     FSNIDILEVSKNNVDSTEDIYHKFCELDYLSKLVSIDKSVDSKKIIHSNNYLSFFVKK
                     ENLRPDKNNNVKLTEEIIDNYYDALLNPRIKYKSDKRKKEIYDSIENKYGKVDENKLN
                     KIRLWIKTNIFDLVESVKKDKNYLKIFFDEKIELYNDENQKYLYPNIYNKNDFNVIID
                     GKNYGLPNDNMQLNEKKPFLKLKTRIRNSTPYLISDDEVLLQKAFFDYLTNKAANGEE
                     VIYISSEKGIHRKTDIPNEFSGYILRIKKGKELEIHDFDTVVNLNTKIKRINVECIIP
                     IEYERHNLKPNLEIGYINNLIKLEKTIDTVFFNKFMCNSYFKEIKNINLSDLVLRDIL
                     IRHREGLYTWFYKGRDSIVKQTFSNYSMGIIENSIKNNNYIRAKEQYNLRIAIINYFH
                     GGSNMADKIKVISESLFEKINSIKTKCIQSDEEYYFAVGQLASYFISKNKSKNKNHSL
                     INPILNAQNRKKIMLEIEKLFKKYNYDISYDNNRRFKNLYSMIVGYEVEEKKVNRDLL
                     IGGYLYYNLIYTKSEENENE"
     gene            2603..3598
                     /locus_tag="KNP54_003504"
     CDS             2603..3598
                     /locus_tag="KNP54_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I CRISPR-associated protein Cas7"
                     /protein_id="HBF0894364.1"
                     /translation="MKMNRRVYGVLGIKSIMSNWNADFSGYPKTTSTGEVFGSDKALK
                     FPMKKMWENEGEKVLYVKSLKIDESKKGEIKIRPKSLKERYEELFDIEDLKLEKNQQK
                     VLENLFKAIDVKNFGATFAEEGNNIGIMGAVQIGQGFNKYEDINVEEQQILSPFRDPK
                     AKDKKKSTNEEEKEDANSTTLGKKIVSDEAHYFYPFSINPKAYEVFVNMGVTDGYTKN
                     DYKKFKEAALVSATAFNTNSKLGCENEFALFVETDEELYLPDLAQYITFEKREKSKDL
                     ICINIIHLIAELKDDIKSVEIYYNPYKIEIKPFKDEILPKIDKVKFMNIFTRKEV"
     gene            3600..4340
                     /gene="cas5b"
                     /locus_tag="KNP54_003505"
     CDS             3600..4340
                     /gene="cas5b"
                     /locus_tag="KNP54_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBF0894365.1"
                     /translation="MEVLKFNLSGKTAFFKKPDVNSIIYFTYGNIHKIALMGILGACL
                     GLGGYNQQSKEDEYPEFYSLLKDIKMSIVPKHEFGYINKKVHIFNNSVGYASKEEGGN
                     LIIKEQWLENVSWDIYIQLEDSTTSRELKRRFLSNKFVYIPYLGKNDHIANISEIEII
                     TDFYKTEDINRVDSFFIREDFEFEKSYFDDNDDYKEPFKYQEKLPYRLHRMTNQYILE
                     TIIFTNMSVKLINKKEVYQVKGLNLIFI"
     gene            4364..6922
                     /locus_tag="KNP54_003506"
     CDS             4364..6922
                     /locus_tag="KNP54_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBF0894366.1"
                     /translation="MYFKKVELFDISNNINNCKNIYAHINKDRKPETLKEHSDLSYSY
                     LMKLCVKKDLSSCLERIENKFFKKDSFLSKNFYREIILNMVYMHDIGKINSSFQFVKM
                     QNKNFKKISLRYTKHSFISSMLYFDYYFEKLKKYDFEEKKILSLFLMINTYTISKHHG
                     VLKSFKEFLFLFKDEFINIKENFKDLFKNNYNLELKSVPKTIEKMVRGVEAYLDDSHI
                     KDNLAIDLYIYSKLMFSIVTSCDFYATSEYNSGNSIDDFGTIDNYNKYYDVLKKSEIY
                     KGMKKYREYLNNNSECPYKENDINRLRTEMSIEAEDAITHNTRKRIFYLEAPTGSGKT
                     VTSINLALKSIELNQSLKKIFYIFPFNTLVEQTKDVFINEIFNSVKDIQKDVVVINSI
                     TPIQTEDKEEDNKNVEYCVTKQEIDYDKSLLNRQFLHYPIVLTTNIGFFNYLFGVSRE
                     ECFPLIHMINSVIILDEIQNYKNEIWKEIILFLEKYADILNIKFIIMSATLPRLNKLG
                     CNDDNFAYLVKNREKFFKNHLFKDRVNISFEMLNSEINDIEEISEKVIEEAEIYNKIL
                     IEFIKKSSALKFYKNIKEKLKYKLEDVFLLTGDDNKLERKKIINKIKDMNSVILVATQ
                     VVEAGVDIDMDLGFKDISTIDSDEQFLGRINRSCKKLNSKVYFFNLDDASKIYKKDVR
                     KERHLTLNEESNRKIILDKDFEKYYDKIIARIEENKHKHNDKNIEVFIKDIVGNLNFT
                     EVKKWMALIPDLKEYTIFLNTIVKDESGNMIVGSDVWYEYISLLKNDNVEYSEKRVKM
                     SEIMEKLDYFTYKVQKFDNSFNDLVGDIFYIDDGSKYFTEGKFDRSKFNQNEFL"
     repeat_region   7112..9851
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7112..7141
                     /rpt_unit_seq="gttaaacagtaacatgagatgtatttaaat"
     gene            9936..10430
                     /locus_tag="KNP54_003507"
     CDS             9936..10430
                     /locus_tag="KNP54_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBF0894367.1"
                     /translation="MKITGTLINYYFHCKRQCWLLGNRINLEENSEDVKIGRLLHELK
                     EEKTKYKEIAIENIKIDKLTREYLVEVKKSDADIEAVKWQVLLYLKKLKEKGIVRKGK
                     IEFIEKNKTNKKIVFVDLSEVSEEQLISIEREIVNLINSDKAPCPDLKKGCKKCAYYE
                     YCYI"
     gene            10465..11463
                     /gene="cas1b"
                     /locus_tag="KNP54_003508"
     CDS             10465..11463
                     /gene="cas1b"
                     /locus_tag="KNP54_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBF0894368.1"
                     /translation="MGKTKYITSMGELTRKDNSICFRKNGRNVYIPVENTSEIFCLNE
                     VSLNSKLLDFLSRANIVVHFFNYYGGYSGTFYPKEYLISGKVTVAQVKTFEDRREEIA
                     KSIVNGIRINAINTLSHYYKHGNSEIQPLLSHLKKDSINKLEKSNNIKEILSVEGDIW
                     QTFYTSFKYILREEFIFNKRVKRPPDNPLNAMISFGNSILYAKTVTAIYNTHLNQSVS
                     FLHEPSESRFSLSLDLSENFKHVITFKTIFDLVNNRKINIEKHFDKNLNYCVLNDEGK
                     QIFINSLEERLESVKEHPKLKRKVSLKTCIKLDAYKMLKCIMEEKSFIPYNIKDGL"
     gene            11674..11964
                     /gene="cas2"
                     /locus_tag="KNP54_003509"
     CDS             11674..11964
                     /gene="cas2"
                     /locus_tag="KNP54_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBF0894369.1"
                     /translation="MKKKNNLNYNYVFVVYDVGEKRVSKVFKVCKKYLSHFQKSVFRG
                     EITPSKIMSLKRDLENIIDKDNDFVCIIKLMNSNTFEEEILGNNSNCENMIL"
BASE COUNT         5265 a         1070 c         1855 g         4060 t
ORIGIN      
        1 ttttttgaaa ctttgtgatt ttatttgtcg aataaaaaat aaaaaatttt aaaggaaaaa
       61 gttaaaaaat aaagaatttt ataactataa attatatttt agagtttatt gttattaaat
      121 agatgaaaaa atcctaatat ggattatcag aaaatgagga ggttgttaat tgataaaatg
      181 tcttgaaatg tctgtaaaag tgtatcttct tgaaaatatt tctttagata atacatcaaa
      241 agaaatacgt aaattaatag atgatacatt aattatagaa gaaaaatata aggaatttca
      301 taataaagct ggatttaaga attattcttt taatttatta tacccattag aaaaagataa
      361 ggtttataag aaggattgta tatatacttt tattattaga actgtagata gtgaattagg
      421 aatgtatttt atgaataatt taaaaaatca gcattctgat aaaataaagg ttattacaat
      481 gagtaaaaaa gtgatcccta aaaaacatat agaaagtatt tactctgtca ctccaataat
      541 agctaaattt gaggatgggt attggagaag taataaaaca gtagaagatt tagaaaaaag
      601 aatcagagaa aatttaataa aaaaatataa tgaatttact aacagtaaaa tagatgaaga
      661 ttttgaatta tttcaagtta ttaaatttat aaataggaaa cctatttcta ctaaatataa
      721 gaatatatct ttacttggtg ataaaataag ttttaaagta tcagaaaatg atatggctca
      781 ggaaattgca aattttgcac ttggagttgg agtcggagaa attaattctc gtggatttgg
      841 ttttgtaaac tatagatggt tataggaggt gaaaacttgt taaaggattg tttagagatt
      901 tttgaaaaag aatacaaatc tttaggaaat agattgataa ctgatagcta tgtcctatcc
      961 tatggaacat atatattggt gaaaaatttt tcgaatatag atatattaga agtttctaaa
     1021 aataatgtgg atagtacaga agatatatac cataaatttt gtgaactgga ttatttatca
     1081 aaactggtgt ctatagataa atcagttgat tccaaaaaaa taatacatag taataattat
     1141 ctttcatttt ttgtaaaaaa ggaaaactta agacctgata aaaataataa tgtaaaactt
     1201 acagaagaaa ttattgataa ttattatgat gctttgttaa acccaagaat taaatataaa
     1261 tctgataaaa gaaaaaaaga aatctatgat tcaatagaaa ataaatatgg taaagtggat
     1321 gaaaataaat taaataaaat aagactatgg ataaaaacaa atatatttga tttagttgaa
     1381 tctgttaaaa aagataaaaa ttatttaaaa atattttttg atgaaaaaat agagttatac
     1441 aatgatgaaa accaaaaata tttatatcca aatatatata ataaaaatga tttcaatgta
     1501 attattgatg gtaaaaacta tgggttacca aacgataata tgcaattaaa tgaaaaaaag
     1561 ccatttttga aattaaaaac aagaattaga aattcaactc cttatttgat tagtgatgat
     1621 gaagttttgt tacagaaagc tttttttgat tatctaacga ataaagcagc gaatggagaa
     1681 gaagtaatat atataagtag cgaaaaggga attcatagaa aaactgatat accaaatgaa
     1741 tttagtggtt atatactgag aataaaaaag ggtaaagaat tagaaataca tgattttgat
     1801 actgtggtaa atttaaacac taaaataaaa agaataaatg tagaatgtat aataccaata
     1861 gaatatgaaa gacataattt aaaaccaaat ttagagatag gatatattaa taatcttata
     1921 aaattggaaa aaacgattga tactgtattc tttaataaat ttatgtgcaa tagttatttt
     1981 aaagaaatta aaaatataaa cttaagtgat ttagttctaa gggatatact tattagacat
     2041 agagaaggtt tatatacctg gttttataaa gggagagata gtatagtaaa gcaaactttt
     2101 tcaaactatt ctatgggtat aattgaaaat tctataaaaa acaataacta cataagagca
     2161 aaggagcaat ataatttaag aatagctata ataaattatt ttcatggagg aagtaatatg
     2221 gcagataaaa taaaagttat tagtgaatct ttatttgaaa aaataaattc tataaaaacg
     2281 aaatgtatac aaagtgatga agaatattat tttgcagttg ggcaattagc atcgtatttt
     2341 atatctaaaa ataagtcaaa aaataaaaat cattctctga ttaatcctat actaaatgca
     2401 caaaatagaa aaaaaatcat gttagagata gaaaaattat ttaaaaaata taattatgat
     2461 ataagttatg acaacaatag gcgatttaag aatctatatt ctatgattgt aggatatgag
     2521 gtagaagaaa aaaaagttaa tagagattta ttaattggtg gatatctata ttacaattta
     2581 atatacacaa aaagtgagga gaatgaaaat gaatagaaga gtatatggag tattaggtat
     2641 aaaatctata atgtcaaact ggaatgctga tttttctgga tatccaaaga cgacatcaac
     2701 aggagaagtt tttgggagtg ataaagcact taagtttccc atgaaaaaaa tgtgggaaaa
     2761 tgaaggtgaa aaagttttat atgttaaatc attaaaaata gatgaatcta agaaaggaga
     2821 aataaaaatt agaccaaaat cattaaaaga gagatatgaa gaattgtttg atatagagga
     2881 cctaaaacta gaaaagaatc aacaaaaagt actggaaaat ctatttaaag ctattgatgt
     2941 taaaaatttt ggtgcaacat ttgcagaaga aggaaataat ataggaatta tgggcgcagt
     3001 acaaattgga caaggattta ataagtatga agatattaat gttgaagaac aacaaatatt
     3061 atccccattt agggatccaa aagcaaaaga taagaaaaag tcaacaaatg aagaagaaaa
     3121 agaagatgca aattcaacta cattaggaaa aaaaatagta agtgatgagg ctcattactt
     3181 ttatccattt tcaataaatc caaaagctta tgaagttttt gttaatatgg gtgtgactga
     3241 tggatatact aaaaatgatt ataaaaaatt taaagaagct gctttagtaa gtgcaactgc
     3301 attcaataca aattcaaagc ttggttgcga aaatgaattt gcattatttg ttgaaactga
     3361 tgaagagtta tacctaccag atttggcaca atatataact tttgaaaaga gagaaaaatc
     3421 aaaagattta atttgtataa atataattca tcttatagca gaattaaaag atgatataaa
     3481 gagcgttgag atatattata acccatataa aatagaaata aagcctttta aagatgaaat
     3541 attacctaag atagataaag ttaaatttat gaacatattt acaagaaaag aggtataata
     3601 tggaggtttt gaaatttaac ttaagtggaa aaactgcttt ttttaaaaaa ccagatgtaa
     3661 atagcataat ttattttacg tatggaaaca tacataaaat tgcacttatg ggtattttag
     3721 gagcttgttt aggacttggt ggatataatc aacagagtaa ggaagatgag tatccagaat
     3781 tctactcttt acttaaggat ataaaaatgt caatagttcc aaagcatgaa tttggatata
     3841 taaataaaaa agtccatata tttaataatt ctgtaggata tgcatcaaaa gaagaaggtg
     3901 gaaatttaat aataaaagaa cagtggcttg aaaatgttag ttgggatata tatatacaat
     3961 tagaagattc aactacaagt agagagctta aaagaagatt tttatctaat aaatttgtat
     4021 atatacctta cttaggcaaa aacgatcata tagctaatat aagtgaaata gagataatta
     4081 ctgattttta caaaacagaa gatattaaca gagtggacag tttctttata agagaggatt
     4141 ttgagtttga aaaatcttat tttgatgata atgatgatta taaagagcca tttaaatatc
     4201 aggaaaaact tccttataga ctgcaccgaa tgactaatca atatattttg gaaactatca
     4261 tatttactaa tatgtcagtt aaattgatta ataaaaaaga ggtatatcaa gtaaagggtt
     4321 taaatttaat ctttatttaa atttataggt ttaggagaat tatatgtact ttaaaaaagt
     4381 tgagttgttt gatataagta ataatataaa taattgcaaa aatatttatg ctcatataaa
     4441 taaagacagg aagccagaaa ctttaaaaga acattcagac ttatcatact catatcttat
     4501 gaaattatgt gtaaaaaaag atttaagctc ttgcctagag agaatagaga ataaattttt
     4561 taaaaaagat tcttttttaa gtaagaattt ttatagagag attatcttga atatggttta
     4621 tatgcatgat ataggtaaga ttaattcttc atttcagttt gtaaaaatgc aaaataaaaa
     4681 ttttaaaaaa atttcactta gatatactaa acattctttt atctcttcaa tgctatattt
     4741 tgattactat tttgaaaagc ttaaaaaata tgattttgaa gaaaaaaaaa tattgagttt
     4801 atttttgatg ataaatacat atacaatatc aaaacatcat ggggttctga agtcatttaa
     4861 agaattttta tttttattta aagatgagtt tataaacatt aaagaaaatt ttaaagattt
     4921 atttaaaaac aattataatt tagagcttaa atcagttccc aaaactatag aaaaaatggt
     4981 aagaggtgta gaagcgtatt tagatgatag ccatataaag gataacttag ctatagactt
     5041 atatatatat tcaaaattga tgttttcaat tgttacatct tgtgattttt atgctacatc
     5101 agaatataat agtggtaatt ctatagatga ttttgggaca attgataatt ataataagta
     5161 ttatgatgta ttaaaaaaat ctgaaatata taaggggatg aaaaaatata gggaatactt
     5221 aaataacaat agtgaatgcc catataaaga gaatgatata aacagattga gaacagaaat
     5281 gagtatagaa gctgaagatg caattacaca taatacgaga aaaagaatat tttatttaga
     5341 agcaccaact ggaagtggaa aaactgttac atctataaat ctagcactga aatctataga
     5401 gttaaatcaa tctttaaaaa agatatttta tatatttcca tttaacacat tagtagagca
     5461 aacaaaagat gtatttataa atgaaatatt taattctgtt aaagacatac aaaaagatgt
     5521 tgtagttata aattcaataa caccaataca aacagaagat aaagaagaag ataataaaaa
     5581 tgttgaatat tgtgttacta aacaagaaat tgattatgat aaatcattgt taaatagaca
     5641 atttttacac tatcctatag tacttacaac taatataggt ttttttaact atttgtttgg
     5701 tgtatcaaga gaagaatgtt ttccattgat acatatgata aatagtgtaa ttatattaga
     5761 tgaaatacaa aattataaaa atgagatatg gaaagaaatt attttgtttt tagaaaaata
     5821 tgcagatata ttaaatataa aatttattat aatgtctgca actttaccta gattaaataa
     5881 attaggatgt aatgatgata attttgcata tctagtaaaa aacagagaaa aattttttaa
     5941 aaatcacctt tttaaagata gagtaaacat aagttttgag atgttaaatt cagaaattaa
     6001 tgatattgaa gaaatatcag aaaaggttat agaagaagca gaaatatata ataagatact
     6061 gatagagttt ataaagaaat catcagcact aaaattttat aaaaatatta aagaaaaatt
     6121 gaagtataag ttagaagatg tttttttatt aacaggtgat gataataaat tagaaagaaa
     6181 aaaaataata aataaaatta aagatatgaa ctctgtaatt ttggttgcta cacaagttgt
     6241 agaggctgga gtagatatag atatggattt gggatttaaa gatatatcta caattgattc
     6301 tgatgaacaa tttttgggaa gaataaatag atcttgtaaa aaattaaatt caaaagtata
     6361 cttttttaat ttagatgatg caagtaagat atataagaaa gatgttagaa aagagagaca
     6421 tttaactctt aatgaggaaa gtaatagaaa aattatttta gataaagact ttgaaaagta
     6481 ttatgataaa ataatagcca gaatagaaga aaataagcat aaacataatg acaagaatat
     6541 agaggttttt ataaaagata ttgtgggaaa tttgaatttt acagaggtaa aaaaatggat
     6601 ggctttaata ccagatttaa aagagtatac aatcttttta aatactatag ttaaagatga
     6661 atctggaaat atgattgtag gaagtgatgt atggtatgaa tatatatcac tactaaaaaa
     6721 tgataatgtt gagtattctg aaaagagggt gaaaatgtct gaaattatgg aaaaactaga
     6781 ttattttacg tataaagttc agaaatttga taattcattt aatgatttag ttggagatat
     6841 tttttatatt gatgatggaa gtaagtattt tacagaggga aagtttgata gaagtaaatt
     6901 taatcaaaat gaatttctat aatgtattta gattatatag agaatattta tcccaagtta
     6961 attaattaga attagtttaa aactattgaa atatagatat tttatagctt atatattttt
     7021 tctaggatta gctgggataa aaaatctgta tattagtgtt ttcagtgtat ttaaggggat
     7081 tatattttta agaagtactg attttaaagt ggttaaacag taacatgaga tgtatttaaa
     7141 tttttactac ataattaaat cgtagtcaat accgtacagg ttaaacagta acatgagatg
     7201 tatttaaatc tctgaatagc caatcaactt tgctgcatta ctcttgttaa acagtaacat
     7261 gagatgtatt taaatgataa tagttatata tattttttac aatatattat tgttaaacag
     7321 taacatgaga tgtatttaaa tttacttctc ctgttttgaa atctatatat tcatcatgtt
     7381 aaacagtaac atgagatgta tttaaatata atattgatac aaatattttg ggtaaatgga
     7441 cttgttaaac agtaacatga gatgtattta aattcgatat ggtaacaaat ttataaaaga
     7501 tatagaatgg gttaaacagt aacatgagat gtatttaaat tagtaaaacc agatggaact
     7561 gttgtaatac caccaaagtt aaacagtaac atgagatgta tttaaattta aaaacatctt
     7621 gaggaatatc tttaacagta attgttaaac agtaacatga gatgtattta aatgcatttt
     7681 caggtgcatg ataaataggt aaattagatg ttaaacagta acatgagatg tatttaaatt
     7741 ttttgtaatt agccagatta tcaactccca aaatagttaa acagtaacat gagatgtatt
     7801 taaattaaat atcgtccttc gtagttaaag caacaccaga aggttaaaca gtaacatgag
     7861 atgtatttaa atcgtaaaca aaatttatca agagaagaat ttctaaggtt aaacagtaac
     7921 atgagatgta tttaaattta tatttgataa gagtatcaaa tcgacttaaa atagttaaac
     7981 agtaacatga gatgtattta aattcaatct taatacacag acatttttaa aaacaaaacg
     8041 ttaaacagta acatgagatg tatttaaata aatagacaaa tattgaatag ctctgtcttc
     8101 atcaagttaa acagtaacat gagatgtatt taaatatatt tacaaaatct ctaacatatt
     8161 ttttaacttc tgttaaacag taacatgaga tgtatttaaa ttcttttaaa gagtcctcgg
     8221 gagcctcgaa aacttcagtt aaacagtaac atgagatgta tttaaattac tcaaataaat
     8281 ttctaatttg tttatctact aacgttaaac agtaacatga gatgtattta aattagaatt
     8341 tacaacaata taagcctctt taaccataag ttaaacagta acatgagatg tatttaaata
     8401 tgtttttagt agtacattta ataaaacttt ttaaagttaa acagtaacat gagatgtatt
     8461 taaatgaagg aaccgtacct tgataaatca cgaccgtacc cgttaaacag taacatgaga
     8521 tgtatttaaa ttgtatattt gatgttgtta tttctcctgt gtataatgtt aaacagtaac
     8581 atgagatgta tttaaatgaa gttccacccc caccaccccc actactttga gaagttaaac
     8641 agtaacatga gatgtattta aattaacaat agagtaaata taataaacaa gcatacaaag
     8701 ttaaacagta acatgagatg tatttaaatc cccttttgca tggtactaga cacgcatata
     8761 tggtggttaa acagtaacat gagatgtatt taaatacgcc tatatgcgga gtaacagatt
     8821 tttgcctgga tggttaaaca gtaacatgag atgtatttaa atactgtttt gggatagact
     8881 ggaattaaat ggtctgtgtt aaacagtaac atgagatgta tttaaatttt tggaatgaag
     8941 catcaacaga taataaagaa aaagttaaac agtaacatga gatgtattta aatcaaggaa
     9001 acaaaagaga agtgaaaaga aatataatgt taaacagtaa catgagatgt atttaaataa
     9061 tcttttaaat ggaaattaag taataaaaga gagggttaaa cagtaacatg agatgtattt
     9121 aaattcaatt aaataagcat taatcttagt aaaatcaaac gttaaacagt aacatgagat
     9181 gtatttaaat tttcttgtgt taattgaacc cccattttaa gctccagtta aacagtaaca
     9241 tgagatgtat ttaaatcaga atacagcttc tatatctgga tacatttgtc ttggttaaac
     9301 agtaacatga gatgtattta aatgtgaaaa gtaatacagg tatagagtct aaacgctcgg
     9361 ttaaacagta acatgagatg tatttaaatc aatgtatcct cttttttagt tttggagcct
     9421 cttttgttaa acagtaacat gagatgtatt taaattagtt agcacatttt atttcaagcc
     9481 ttaaaacatt cgttaaacag taacatgaga tgtatttaaa ttaatttgca cacttaacct
     9541 ctaatcttaa agtattagtt aaacagtaac atgagatgta tttaaataac acaatattat
     9601 ctttaataga attaaacaaa tgagttaaac agtaacatga gatgtattta aatttttgtt
     9661 ggtcttgtgc ttcttttaaa agctgattag ttaaacagta acatgagatg tatttaaatt
     9721 taaaaagttc tgttattaaa acatccaaac caatcgttaa acagtaacat gagatgtatt
     9781 taaattctgt accatctagc caaaccgttt ttgaagttaa agttaaacag taacataaga
     9841 tgtatctaaa ttactctatc ataaaatttt aatatattaa acaaactaat atgtgatata
     9901 cttatgtata aataacaaaa taaataggtg atgttatgaa aattacagga actttgataa
     9961 attactattt ccattgtaaa agacaatgct ggttgcttgg taatagaata aatttggaag
    10021 aaaatagtga agatgtaaaa ataggtagac ttcttcatga actaaaagaa gaaaaaacaa
    10081 aatataaaga aattgcaatt gaaaatataa aaatagacaa attaacaaga gaatatttag
    10141 tagaggttaa aaagtctgat gctgatatag aagctgttaa gtggcaagtt cttttatatt
    10201 taaaaaagtt aaaagaaaag ggaattgtaa gaaaagggaa aattgaattt atagaaaaaa
    10261 ataaaactaa taaaaaaata gtctttgtag atttgagtga agtatctgaa gaacagctta
    10321 tatctataga aagagaaatt gttaatttaa taaatagtga taaagcacca tgtcctgatt
    10381 taaaaaaagg atgtaaaaaa tgtgcctatt atgaatattg ttatatataa agaggtataa
    10441 gaaacatata aggaggtgtt aatattggga aagacaaaat atattacctc aatgggtgaa
    10501 ctcacaagaa aagataattc tatatgtttt agaaaaaatg gaaggaatgt atatatacca
    10561 gtagaaaata ctagtgaaat attctgtcta aatgaggtat ctttaaattc aaaattactg
    10621 gattttttat caagagcaaa tattgttgtt cattttttta attactatgg tggatatagt
    10681 ggaacttttt atcctaaaga atatttaata agtggaaaag taacagtggc acaggtaaaa
    10741 acctttgaag atagaagaga agaaatagca aaatccatag tcaatggtat aaggattaat
    10801 gcaataaata cattatcgca ttactataag catggaaatt cagaaataca accattatta
    10861 tcacatctaa aaaaagattc tataaacaag ttagaaaaat caaataatat aaaagaaata
    10921 ttatcagtcg aaggagatat ttggcaaaca ttttatactt cctttaagta tattttaaga
    10981 gaggaattta tttttaataa aagagttaag agaccaccag ataatccctt aaacgcaatg
    11041 atatcatttg gtaacagtat tttatatgct aaaactgtaa ctgctatata taatacacat
    11101 ctaaatcaaa gtgtaagttt tttacatgaa ccaagtgaaa gtagattttc tttaagtcta
    11161 gatttaagtg aaaattttaa acatgttata acttttaaaa ctatatttga tttagttaat
    11221 aatagaaaaa taaatattga aaaacatttt gataaaaatt tgaactactg tgttctaaat
    11281 gatgaaggaa agcaaatttt tataaattct ttagaagaaa gattagaatc agtcaaagaa
    11341 catccaaaat taaaacgaaa agtaagttta aaaacctgta taaaattaga tgcttacaaa
    11401 atgttaaagt gtataatgga agaaaaaagt tttattccat ataacataaa agacggatta
    11461 taatttaaac ataaagtaag tattttaata tagaactttg atatatataa gaatgataat
    11521 tatgctatta taagtataca taatatatta ttgaaataat ataagttttt agaagtattt
    11581 taagatgaga aaggagaaaa tactgaaaaa taattattct attataattt gccaaggttt
    11641 tgtatatttt tcagtttaaa tattatatta catatgaaaa agaaaaacaa tttaaattat
    11701 aattatgtat ttgtagtcta tgatgtagga gaaaaaagag taagtaaagt ttttaaagtg
    11761 tgtaaaaaat atctctcgca ttttcaaaaa tcagttttta gaggtgaaat aactccatct
    11821 aagattatga gcttaaaacg tgatttagaa aatattatag ataaagataa tgattttgta
    11881 tgtataataa agttgatgaa ttctaataca tttgaagaag aaatattagg gaataatagt
    11941 aattgtgaaa atatgatatt ataaatctaa ttactatatt tgtaaaaaat aatagcttat
    12001 taaagagtag taaaattggg atataattta tgatagagac tgcaagtaga tttttgtgaa
    12061 aaggatttac ttgcagtatt tttgttatgt ataactgtta acattagtgt acaaaacatt
    12121 atcaatagca tttttctata atgaagaaat actattataa tgggaaaatt ttattaatac
    12181 taggtaataa tatatttaca caagtctata tatattataa ttttcattat aattattcag
    12241 tatttctaat
//
LOCUS       DAEHWO010000105        11777 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEHWO010000105 DAEHWO010000000
VERSION     DAEHWO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11777
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.107"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(348..893)
                     /locus_tag="KNP54_003510"
     CDS             complement(348..893)
                     /locus_tag="KNP54_003510"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0894370.1"
                     /translation="MRVEPIENKKDIEKLKRYFKNKGKIRDLTLITLGLNIGFRIEDI
                     LKLKVKDVYKKREINIKESKTGKRIRKPINDSLKEILDIYCKDKPTNEYLFKSQKGEN
                     EAISTTQAYRIIKKASKACRIKLNIGTHSMRKTHGLHIFKDKGIEVAQRALNHANQID
                     TLTYIGVVQKQADDAIMKLNL"
     gene            complement(909..1157)
                     /locus_tag="KNP54_003511"
     CDS             complement(909..1157)
                     /locus_tag="KNP54_003511"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894371.1"
                     /translation="MEGTKRSYRKIPKLDLRKVKLADVFEKNEPGVFRVKESDEQLLY
                     DCLEETQNIRQEKHIAYAIRFRGKSVYCVFYESPFWDL"
     gene            complement(1513..2148)
                     /locus_tag="KNP54_003512"
     CDS             complement(1513..2148)
                     /locus_tag="KNP54_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBF0894372.1"
                     /translation="MIIGYERVSTRKQDNSRQERVLENEGIKFDKIYKDVITGATKER
                     EALSRMLVEVNKGDTVYCESISRLGRNLKDLIDIIDTLVQKGVRVKILKEGIDTNNNT
                     YKMLLGIFGAVAEMERETIQERTQQKIDQLKEDKKNTGEINTKSGKWFGRQKVTKELL
                     ETNKEFIKYYNKILDGSLKKNEVAKILNVGRTTLYEWIKIYEGGEIKRNRS"
     gene            complement(2738..3106)
                     /locus_tag="KNP54_003513"
     CDS             complement(2738..3106)
                     /locus_tag="KNP54_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004068822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894373.1"
                     /translation="MELDFKFIGQRIKIARIKKKLTQEVLSEKINVSPQHVSNIETGN
                     SSVSLPTLVAIANTLGVSVDELLCDTILSSKAVFENELEEVLRDCNEYEIRFITDIVK
                     ASKKSIRDIKLFQSNLNDRY"
     gene            3222..3554
                     /locus_tag="KNP54_003514"
     CDS             3222..3554
                     /locus_tag="KNP54_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0894374.1"
                     /translation="MDIPKIPQTELKVMKFIWSKNDIVTSKEVAKAMELEYSWKMTTT
                     LTILSRLVIKHFLASERIGRMTHYTILIAKKDYKISETKRFLNDIHSNSLESLLNSLK
                     DCNITHKK"
     gene            complement(3702..4139)
                     /locus_tag="KNP54_003515"
     CDS             complement(3702..4139)
                     /locus_tag="KNP54_003515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894375.1"
                     /translation="MRVKNIISIFVCALIIIMSVNVVSFAEQFNSSDIIFMEDGKEEI
                     NPFSVYILNGRCNLSFSNGKANVNASVVGKSGVTRTSIVTKLQELKGGSWVNLKTSTK
                     KTGGKTCSVLNSYSVTKGHTYRAVAIITAENESKTLISTSQKY"
     gene            complement(4208..4909)
                     /locus_tag="KNP54_003516"
     CDS             complement(4208..4909)
                     /locus_tag="KNP54_003516"
                     /inference="COORDINATES: protein motif:HMM:NF025643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HBF0894376.1"
                     /translation="MNKDKLDIEKLLYEQLPKIEEKILYELPCDEDIDYEFSIEFESK
                     MDKIIKENEKKVKKNTYKNLKKIAIVFIIILSSIVTITTIKTEAFPENLIRIMKKVYK
                     EFTDYNFINPHKSNVSFKYIEPKYISTGYKEVERIEEENYLSILYKDKLDNYIIYQMM
                     LYSRDVIVLDTEDAFVENIKFNNQYAQYVEKGNTQQLLWHDKNNIYMLSKELPTKKIT
                     KKDKKEFIKIAKNIK"
     gene            complement(4902..5447)
                     /locus_tag="KNP54_003517"
     CDS             complement(4902..5447)
                     /locus_tag="KNP54_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0894377.1"
                     /translation="MLIYLAIIDSKEERIKFEEIYIKYKKLMFYVANQILKDDVLAED
                     AVHSSFLKIIDNLDKVNDVNSPKTKGFVVIIVKRISINIYNRRKKEEISNINDDNYKF
                     SSLDLSIEKLGECSYLGEALKKLSETDLQVILLKYSHGFSIREISKLLNIKEVNLYKR
                     NKRALEKLKKILSEMEALSNE"
     gene            5583..6311
                     /locus_tag="KNP54_003518"
     CDS             5583..6311
                     /locus_tag="KNP54_003518"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894378.1"
                     /translation="MKSKRINKMLATTMTMAMLAIPAVTATSYAMESTGLGTEYTYNN
                     ESKQQEEWVKSFDTETGKEILLNKTTNEKVSEVYENVNGKLVKLSINEALEKFNLNEE
                     IITKSPKSIFGVSSVKKITGSARKISQDVSGGKQGATISIGNSTTVTESFTVGGTTEA
                     IKAAVRANAGFTWSKSLTRSVTTTHKVPAGKIGYVAFKPYYKEVRGTVNGILAGTSIT
                     QKIVAKSPLKAGKVCDGLEYLAYK"
     gene            6337..6585
                     /locus_tag="KNP54_003519"
     CDS             6337..6585
                     /locus_tag="KNP54_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004035436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894379.1"
                     /translation="MENKNMYLRVSLILAVLGFIILFFNNDLALSLKATYLADKGFED
                     IVENQILKNYSYMFLIIGGVLFSIGIYNLTKLKQINKK"
     gene            complement(6771..9380)
                     /locus_tag="KNP54_003520"
     CDS             complement(6771..9380)
                     /locus_tag="KNP54_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBF0894380.1"
                     /translation="MKIDIKQLIDIIKNANIDELYLRDIGVDTTQKRNVPCPIHGGKD
                     KNFQFDLNKRIYTCYSHNCVVGADIIELCRTYERFERPIEAILFLANKYNISLPINKS
                     KTNIKKTNNTIKNIYIKKKDINSFIEEKKQEAFKNNDIELAFEFECMTDKDKRKYYLD
                     NNIKIKSMLEKQNYSSYKADSIINIDKYISENLKGIRESIKHATEGKNVLMVAPTGSG
                     KTYSIINTLKELDIKALFIFPNSANVQQAIVEYKIAGAYDKIPTKHALEGNKLVAMTW
                     DKTEQLLKEDLSEYIIVIDEIHQTYTDAFRSKAIKSLNNITNKCRGRLDITATPSKLE
                     FEIYNKVIEYKQNIQTEYKVKLYDKINIGKVIEILNNSNNSMLLKDSISTLNYISKKV
                     NKKSGVVISDTKDTSKLYDRIVSYSDMEGYEVLLNTSVITAGVNINNPNVTDIIVIGE
                     KDVGKIKQYVARARGAKSINVHIFNSYKTTNEDSNVYSVEWCINENIKDVESLTNIYN
                     KASKRDLPYRAIGIDISPINIKNIDSNIYYDKKDMCYKTDKLYIKSNAYNNYYQTRTI
                     NSFKVLLEEYFNKIEIVETEKETKKIEEEIKEHEEAIKEFKKSAIEQLEGHKKYLVGY
                     SEIKKSMTSSNLLKYHHDMRIDNNICLKYYMEHDLYSLIINNNCRKTIDLFSDFVLDN
                     SYSIDLSWKLATMSDEKRNLFFEQINTTIYRKINKKYANSLLNDDNIGTYTYNYINFN
                     FGVGTSYTKEHLEALAVDLQTFLATKKKLTIKKISLILQSIFVIEVKQHRGVTGLPYK
                     YYKNILPNPVTDKKVIRVYTIKKHIDIEDIKKELGLIDNDLSIEHLVEARINKLLNAI
                     DETEKEVLLEGLI"
     gene            complement(9710..10012)
                     /locus_tag="KNP54_003521"
     CDS             complement(9710..10012)
                     /locus_tag="KNP54_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894381.1"
                     /translation="MLKDDLLRIGFDTYGVNLEDKLLENNEIYLNDKKESERIMNRLL
                     EILEEKEHKKMLIDFEEKVFGNSVIEKEYAYRMGVLDGLDLAEFIDLNKKLCLKRN"
     gene            10181..10384
                     /locus_tag="KNP54_003522"
     CDS             10181..10384
                     /locus_tag="KNP54_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894382.1"
                     /translation="MDIQINKLLENQNKTRYWLAKQIGMTHQNLTKLANNNTNSIKFD
                     SLEKICMALKCSPNELFGWEQDK"
     gene            10464..11009
                     /locus_tag="KNP54_003523"
     CDS             10464..11009
                     /locus_tag="KNP54_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894383.1"
                     /translation="MDRYTFDNLPIKEQIQYINNKLLEGNTLTNTCKDIGIGRTTIRN
                     RFKQHGYEFNPTKKLYISIIEVVELESSSKVVAGDTSNDNTLVDATNIDFNNILSKFN
                     DMNNKLNEVYSWYESQSSNKVVGADKLNIDDFKGNIVVRSYKVYEDIQKEFVAFCEAN
                     KKYRVQDIISQALRDFMDKYK"
BASE COUNT         3901 a         1821 c         1281 g         4774 t
ORIGIN      
        1 aaaaaaaaat aaccatacgc attgatttta cttaaattaa aagtgttttt cgagttgttt
       61 tttcacttag tttagtaatt ttgaaatatt ataatattaa gcttcaatat gtatctatta
      121 tcatttaata atcaattaat aatagatatt ttttctaaac aagataaaaa caatatctat
      181 accagtaata gcaatagata gaagtatata aaaaaatgta cgattactat aaactattac
      241 atttatttta gttatcttta tccattgcaa ttacttatac ataagcttat ttacttaatc
      301 attaactata aaatgtaaaa acaacaaaga aaatcataca tttttaacta taaattaagt
      361 ttcataatgg catcatcagc ttgtttttgt actaccccaa tataagttaa tgtatctatt
      421 tgattagcat ggtttaaagc tctttgtgcg acttcaattc ctttatcctt aaatatatgt
      481 aaaccatgtg ttttcctcat gctatgagta cctatattta attttatcct acaagctttt
      541 gaagcttttt taataattct atatgcttgt gtggtgctta ttgcttcatt ctctcccttt
      601 tgacttttaa ataagtattc attagttggt ttatctttac aatatatatc taatatttct
      661 ttcaaactat catttatagg ctttcttatt cttttccctg tcttactttc ttttatattt
      721 atttctcttt ttttgtatac atctttaact tttagtttta aaatatcctc tatcctaaag
      781 ccaatattta accctaaagt tattagggtt aaatctctta ttttaccttt atttttaaaa
      841 tatcttttaa gcttctctat atctttttta ttttcaatag gttctactct catttaactc
      901 actcctattt ataaatccca aaatggactc tcataaaaaa cacaatatac actttttcct
      961 ctaaatctaa tcgcataagc aatgtgcttt tcttgtctaa tgttttgagt ttcttctaaa
     1021 caatcatata agagttgttc atcactttct tttactctaa aaactcctgg ctcattcttt
     1081 tcaaatacat ctgctaattt tacttttctt aaatctaatt ttggtatttt cctataactt
     1141 cttttagttc cttccataat ttcccctctc atttttctat ttatataaat tattttaata
     1201 tatttttaca atccaaaagt ctctattttg ttcaaaatat gtagtttttt attacttgtt
     1261 aatttacaaa atcatttgat gtgattttat cattctatct actataccaa aaaaaatctt
     1321 attttcttaa gtaaatcaaa atttaatatt tataataaaa aaaagagcct aaaaaattag
     1381 actcttgttt gcaaaagcta ttaaattgta aagctttcaa taatataatt atactatata
     1441 ttttgttctt attttgtcta attttgttca atttttgttc aaaataataa cacttaaata
     1501 tattataatc aattagcttc tattcctttt tatttctcca ccttcatata tctttatcca
     1561 ctcgtaaagt gtagtcctac caacatttaa tatttttgcc acttcattct tctttaagct
     1621 tccatcaagg attttattat aatattttat aaactctttg ttagtttcta aaagctcctt
     1681 cgttactttt tgtctaccga accattttcc actctttgta tttatctcgc cagtattttt
     1741 cttatcctct tttagttggt ctattttctg ctgtgttctc tcttgaattg tttctctctc
     1801 catttctgca actgccccaa atataccaag taacatcttg tatgtattat tatttgtgtc
     1861 tataccttct tttaatattt ttactcttac acctttttga actaatgtat ctataatatc
     1921 aattaaatct tttaaattcc ttcctaaacg gcttatagac tcacagtaaa cagtatcccc
     1981 cttatttact tctactaaca ttctgcttaa tgcttctctt tcctttgttg ctcctgttat
     2041 tacatcttta tatattttat cgaacttaat tccctcattc tctaaaactc tctcttgtct
     2101 gctgttatct tgttttcttg tacttaccct ttcatatcct attatcataa ccctaccccc
     2161 atttgtcttg ttataataat tatacaatat attttttgtt cggtcaaact atatttttca
     2221 tttttgcaat gccgaacata ttttattgtt gatttccaat gattctatgt aaaaatcata
     2281 caaatattgt gtgtacggtc aaacgttggt ttttccgaac acgaacatat cacctttttt
     2341 atatcaacta ttccttaaat attttatata aaatcgccaa aatcttttta tattttttag
     2401 gcaaccaagt ttttaaaaca aaaatggtat atcagtaaga attatgtttt cacacaatat
     2461 aattcttaat gatataccat ttaagaacct cataagaggt agatagagat aattacataa
     2521 tcatcacata cgttttatca aatctgtttt gtaatagggt ttatacttaa ataataacaa
     2581 aaataccgta ttttttctac atttatactt tttttgttga tagtaaaata tggaaattag
     2641 tcatattttc agttattaac tcataagttt atacaacttt tatttaaata taataaaaac
     2701 atcaataata attaaattat tgaagcatat atttatatta atatctatca tttaaatttg
     2761 attgaaacag ttttatatct ctaatggatt ttttagaagc ttttacaata tcagttataa
     2821 atcttatttc atactcatta caatccctca aaacttcttc taactcattt tcaaagacag
     2881 ctttagaact taagattgta tcacataata attcatcaac cgacacccca agagtatttg
     2941 caatagcaac gagcgttggc aaacttacac ttgaatttcc cgtttcaata ttgctgacat
     3001 gttgtggact aacattgatt ttttctgata aaacttcttg tgttagcttt ttcttgattc
     3061 ttgcaatttt tatcctttga cctataaatt tgaaatcaag ctccatatgc gtattccctt
     3121 cctacaagta ttcacacata ttgtaacctt tcccaaagta tattataata aattaataga
     3181 atgtttcatt atgatagtta tagtgtatag aaaggaatta tatggatata ccaaagatac
     3241 ctcaaacaga actcaaagtc atgaaattta tttggagcaa aaacgacatt gtaacatcta
     3301 aagaagttgc aaaagctatg gaacttgaat atagttggaa aatgacaaca accctaacaa
     3361 tcttatcaag gcttgttatt aaacactttt tagcatctga acgaataggc agaatgacac
     3421 attatacgat actcatagca aaaaaagatt ataaaatatc tgaaacaaaa agatttctaa
     3481 atgacataca ttcaaattca ttggaaagcc ttttaaactc tttgaaagat tgcaatatta
     3541 cacataaaaa atagtacatg agtataaatt atattattat acctatgtac tatttaagtt
     3601 tttctataat gttcctatat ctatctaatt ttgattgatt tagatacttc tgtagtagtt
     3661 ttcaaaacgt ttcttaactc ttgtaagtgt attttctttt tttaatattt ttgagatgta
     3721 cttattaatg tttttgactc attttcagca gtaattattg caacagctct ataagtatgt
     3781 ccttttgtca cagaatatga gtttaaaaca gaacaagttt ttcctccagt tttctttgta
     3841 gatgttttta aatttaccca acttccgcct tttaattctt gtaacttagt tacaatagat
     3901 gttctagtta ctccagattt tccaacaaca gaagcattta catttgcttt tccattagaa
     3961 aatgataaat tacatctacc atttaatatg taaactgaaa aaggatttat ttcttcttta
     4021 ccatcttcca taaaaataat atcagatgaa ttaaactgtt cagcaaaact aacaacattt
     4081 actgacatta ttattatcaa cgcacataca aatattgaga ttatattttt tactctcatt
     4141 aagtacctcc ttataaaatc ttatatattc aatataacaa ctaactagca ctattttaga
     4201 caaaaattta cttaatattt tttgcaattt taataaattc ttttttatct ttcttagtta
     4261 ttttttttgt aggtagctct ttagataaca tataaatatt atttttatca tgccacaata
     4321 attgttgagt atttcctttt tcaacatact gtgcatactg attattaaat tttatattct
     4381 caacaaaagc atcctctgta tccaagacta taacatccct agaatataac atcatttgat
     4441 aaattatata gttatctaat ttatctttat ataatattga tagataattt tcttcctcaa
     4501 ttctctcaac ttctttatat ccagtagaaa tgtatttagg ttctatatat ttaaatgata
     4561 catttgattt atgagggttt ataaaattat agtctgtaaa ttctttatat accttcttca
     4621 ttattctaat taaattttct ggaaaagctt ctgtttttat agtagttata gtgactatac
     4681 ttgataaaat tattataaaa acaatagcaa ttttttttaa gtttttatag gtgttctttt
     4741 ttactttttt ctcattttct tttataattt tatccatttt actttcaaat tctatagaaa
     4801 attcatagtc aatatcttca tcacaaggta attcatacag tattttttct tctatttttg
     4861 gaagctgttc gtataataat ttttctatgt ctaatttatc tttattcatt tgataatgcc
     4921 tccatttcgc ttaaaatttt ttttaatttt tctaatgctc ttttatttct cttatacaaa
     4981 ttaacctctt ttatattcag tagtttagaa atttctctga tagaaaaacc atgactatat
     5041 tttaagagaa tcacctgtaa atctgtctct gacagttttt ttaaagcttc tcctaaataa
     5101 ctacactcac ctaacttttc aatcgataaa tctaaagagc tgaatttata gttatcatca
     5161 ttaatattac ttatttcctc tttttttctt ctattatata tatttattga aatccttttt
     5221 actataataa caacaaaacc tttagttttt ggactattca catcatttac tttatcaaga
     5281 ttatcaatta tttttaaaaa tgaactatga acagcatcct ccgctaaaac atcatctttt
     5341 aaaatttgat tagctacata aaacattaat ttcttatatt taatatatat ttcttcaaat
     5401 ttaattcttt cttcttttga atctataata gctaaatata ttaacataaa ttattctccc
     5461 ttaaaaaata ttatccttaa aaaaattata tacaatttat aaaaaattat atataaatgt
     5521 ctaaaaataa aaacttcatt tgttatatat ataaataaaa acataaaagg atggtgtttt
     5581 atatgaaatc aaaaagaata aacaaaatgt tagcaactac aatgacaatg gcaatgctag
     5641 caataccagc agtaacagca acatcatatg caatggaatc aacagggtta ggaacagaat
     5701 atacatataa taatgaatct aaacagcaag aagagtgggt taaatcattc gatactgaaa
     5761 caggaaaaga aatattatta aataaaacta ctaacgaaaa agtttctgaa gtatatgaaa
     5821 atgtaaatgg aaaattggtt aaattaagta ttaatgaagc actagaaaaa tttaatttaa
     5881 atgaggaaat tatcacaaaa tctcctaagt ctatttttgg agtatcaagt gttaaaaaaa
     5941 ttactggttc tgcacgcaaa atatcacaag acgtatcagg tggaaaacaa ggtgctacta
     6001 tatctatagg aaattcaaca actgtaactg aaagttttac tgttggtgga actacagaag
     6061 caataaaggc agcagtaaga gcaaatgcag gatttacatg gagcaaatct ttaacaagaa
     6121 gtgtcacaac tacacacaaa gtacctgcag gtaaaatagg atatgtagca tttaaaccat
     6181 attataaaga agtaagaggt acagtaaatg ggatacttgc aggaacttct ataactcaaa
     6241 aaatagtagc aaaaagtcct cttaaagcag gaaaagtttg tgatgggtta gaatatcttg
     6301 catacaaata ataaataata gaaagagttg attaaaatgg aaaataaaaa tatgtactta
     6361 agggttagtt taatattagc agtattaggc tttataatat tattttttaa taatgactta
     6421 gcattatcac taaaagcaac atacttagct gataaaggct tcgaagacat agttgaaaat
     6481 caaatattaa aaaactattc ctatatgttt ttaataatag gtggtgtact attttccata
     6541 ggaatctata acttaaccaa actgaaacaa attaataaaa aataaataaa ataagaggac
     6601 ttataaatta taagtccttt tattttacac ttataagcta ctttcaacct ttcatgattt
     6661 aacctttatt tatacaacac ccaaaactcg acctcaaaaa gagaacagga cttcgtcccc
     6721 cttaatacaa agcaacattt tttagtacta ttcgtactta agattagcta ttagattaat
     6781 ccttccaaaa gaacctcttt ttccgtttca tcaatcgcat ttaaaagttt atttattcta
     6841 gcttcaacta aatgctctat gcttaaatca ttgtctatta gtcctaattc tttttttatg
     6901 tcctctatgt ctatatgttt cttaatagtg taaactctaa ttactttttt atctgtcaca
     6961 gggtttggaa gtatattttt atagtattta tagggcaacc ctgtgacacc cctgtgttgt
     7021 ttgacttcaa taacaaaaat tgattgtaat attagactta ttttcttaat agttagcttt
     7081 ttcttagttg ctaaaaacgt ctgtaaatca acggctagag cttctaagtg ttcttttgta
     7141 taacttgtac caactccaaa attgaagttt atataattgt aagtataagt accaatatta
     7201 tcatcattta gcaaagaatt tgcgtatttt ttattaattt ttcgataaat tgttgtattt
     7261 atctgttcaa aaaatagatt tcttttctcg tctgacattg tcgcaagttt ccaagatagg
     7321 tcaatactat aactattatc taatacaaaa tcactaaata agtctatcgt ttttctacaa
     7381 ttattattaa ttattaggct atataaatca tgttccatat aatattttaa acagatatta
     7441 ttatctatcc tcatgtcatg atgatatttt aataagttac tgctggtcat tgacttctta
     7501 atttcactat agccaactag atacttttta tgtccttcta gttgttctat agctgatttc
     7561 ttaaattcct taatagcttc ctcatgctct tttatttctt cctctatttt tttagtttct
     7621 ttttcagttt ctactatctc aattttatta aaatattcct ctaatagcac tttgaagctg
     7681 tttattgttc ttgtttggta atagttattg taagcattac tttttatgta taacttgtcc
     7741 gttttatagc acatatcttt tttatcatag tatatattac tatcaatgtt ttttatgttt
     7801 atagggctta tatcaattcc tatagctcta tatggtaagt ctctcttaga agctttattg
     7861 tatatatttg ttaggctctc aacgtctttt atgttctcat ttatgcacca ttcaaccgaa
     7921 tatacattgc tatcctcatt tgtcgttttg taactattaa aaatatgtac atttatactt
     7981 tttgcccctc tagctcttgc aacatactgt tttatttttc ctacatcctt ttctccaatt
     8041 acaataatat ctgttacatt aggattattt atgtttacac ctgccgtgat tacagacgta
     8101 tttaaaagca cctcatagcc ttccatatcg gagtaactaa caattctatc atatagtttg
     8161 ctagtgtctt tagtatctga aataacaact ccactctttt tattaacttt ctttgatata
     8221 tagttaagtg ttgatatact atcttttaaa agcattgaat tatttgaatt atttagtatc
     8281 tctattactt tcccaatatt gattttatcg tataacttaa ctttgtattc cgtttgtata
     8341 ttttgtttat attcaataac tttgttatat atctcaaatt ctaatttaga gggtgttgca
     8401 gttatatcta gtctacctct gcacttatta gttatattat ttaagctctt tattgctttg
     8461 cttctgaacg catctgtgta agtctgatgt atttcatcaa taactattat gtactcgctc
     8521 aaatcctctt ttagaagctg ttcagtctta tcccacgtca tagccactaa cttgtttccc
     8581 tctaaagcgt gtttagtagg tatcttatca tatgcaccag ctattttata ttcgactatt
     8641 gcttgttgca cattcgcaga gttggggaat ataaagagtg cttttatatc cagctctttt
     8701 aatgtattta taattgagta tgtttttcca cttcctgtag gagctaccat taatacgttc
     8761 ttaccttctg tagcatgttt aattgactct ctaatacctt ttagattttc acttatgtat
     8821 ttatctatat taattatcga atcagcttta taacttgaat agttttgttt ttctagcatg
     8881 gattttattt taatattgtt atctaagtaa tactttcttt tgtccttatc agtcatacac
     8941 tcaaattcaa aagctaactc aatatcattg tttttaaaag cttcttgttt cttttcttct
     9001 atgaagctat ttatatcttt tttctttatg taaatgtttt taatagtatt atttgttttt
     9061 ttaatatttg tcttactctt gttaattggt aatgagatat tatatttatt ggctaggaat
     9121 aaaatagctt ctataggtct ttcaaagcgt tcatatgtgc gacataattc aattatatca
     9181 gcaccaacaa cacaattatg gctatagcat gtatatattc ttttgtttaa atcgaattgg
     9241 aagtttttat ccttaccacc atgaattggg caaggaacat tccttttttg agttgtatcg
     9301 actcctatat ctcttaaata tagttcatct atattggcat tttttattat atcaattaat
     9361 tgttttatat ctattttcat ttgtaaaaat cccccttttt tagttagggg ctaatcaagt
     9421 tttatcaagc tatgtattta cattctgccg taaatctcgt ataattaaca tataaaagaa
     9481 taaggaaata tatattttat atgttaatta agcctaagtg attagctcct agtattaacc
     9541 cctagtggct aactcctaat cttgattaac ccttaaatgg aaagaatgag tggatgccgt
     9601 caaacaaata ctcgttcttt ttcgtttttt ttgttattag tattatatca ctattaaagt
     9661 tataattcat tgtttagaat tatttttctg acggttttaa tatatatttt taatttcttt
     9721 tcaagcataa ttttttattt aagtctataa attcagctag gtcaagccca tctaaaaccc
     9781 ccattcggta tgcgtattct ttttcaatta cactgttacc aaatactttt tcctcaaaat
     9841 caattagcat ttttttatgt tctttttctt ccaatatttc taacaatctg ttcattattc
     9901 tttcagattc ttttttgtca tttaaatata tttcgttatt ttctagtagt ttatcttcta
     9961 aatttactcc gtatgtgtca aatccaattc ttaataaatc atcttttaac attactttta
    10021 acactccttt ttatgcacac ttaaatcttt tgcaccccta aatatggtaa tatattctat
    10081 ttattattat gtaattattt actatgtatt gtcaagcata tatattgttt ttggtacata
    10141 tttccgatac tatataataa aaaaggtggc gattaaattg ttggatatac aaataaataa
    10201 attattggaa aatcaaaata aaacacgtta ttggttagca aagcaaattg gaatgactca
    10261 tcaaaactta actaaactag ccaacaataa tacaaattct attaaatttg attctttaga
    10321 aaaaatttgt atggctctaa aatgttctcc taacgagctg ttcggttggg agcaagacaa
    10381 ataaaaaaat ataaatccta aagggtttat ttataactac tagaaaacta ctttagtagt
    10441 tattttattt tggaggttta aacatggata gatatacatt tgataactta cctatcaagg
    10501 agcaaataca atatattaat aacaagctct tagagggcaa tacattaact aacacatgta
    10561 aagatattgg tattggtcgt acaactataa gaaatagatt taaacaacat ggatatgaat
    10621 ttaatccaac taagaagcta tatatatcta ttattgaggt tgtcgaatta gaaagtagtt
    10681 caaaagtagt tgcgggcgac actagcaatg acaatacttt agttgatgca accaatattg
    10741 attttaataa cattttatct aaattcaatg atatgaataa taaactaaat gaagtatata
    10801 gttggtacga atcacaaagt agtaataaag tagttggggc tgataaacta aatatagacg
    10861 attttaaagg caatatagtt gttagaagct ataaggtcta tgaggatatt caaaaagagt
    10921 ttgtagcctt ctgtgaagct aataagaagt acagggtaca agatattatc agccaagctc
    10981 ttagggattt tatggataaa tataagtagt tttacttact ttctgatatt ctaaaaactt
    11041 ttcaatgaaa atctcatttt ttggcttcct gtgaaaaata tgtactcctt ccagtcctct
    11101 atctttattt actttattaa tccgataggg ggcgtattat atatatttct atcgagcata
    11161 tactcatcaa aacatagcat tagtttgatt attatatttc tatttatttt aagattatat
    11221 atacaatttg ccccttaata cattgcaatt actaacttct ttagttttga tattaatatt
    11281 taaatcattc ctttttaaag gtgctataag tgctatatag gcattgcaac ctatatactt
    11341 tttaggggtg cagttgcata tgcaagctct ttatttccca acacttaacc agttataaat
    11401 atttatatcc tttattagcc aaatatagca ttttaaacaa ctccgactat ctttagtagt
    11461 aacattttac atagctttat taatgtattt ttgcatctgc aaccatgttt ttaagttgca
    11521 acaccccacc cccacacctt acacaaaaca atacttatct ccgaagccat atacctacct
    11581 cggttcacat atttttcttc aacagcgtta ttttcagcaa ggggggctaa acattatact
    11641 ttttttcagt gcattaaata gccttacatg tattggtata actttatttc aaacccttaa
    11701 ttgaattgtt tcaatctaaa ttaagtaaat tttaataaga taaaatatat agtttgtaac
    11761 tttatttcaa aatacag
//
LOCUS       DAEHWO010000106        11453 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEHWO010000106 DAEHWO010000000
VERSION     DAEHWO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11453
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.108"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(89..1036)
                     /locus_tag="KNP54_003524"
     CDS             complement(89..1036)
                     /locus_tag="KNP54_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894384.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGYIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            complement(1064..1555)
                     /locus_tag="KNP54_003525"
     CDS             complement(1064..1555)
                     /locus_tag="KNP54_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894385.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            complement(1998..2891)
                     /locus_tag="KNP54_003526"
     CDS             complement(1998..2891)
                     /locus_tag="KNP54_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBF0894386.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            complement(3116..5401)
                     /locus_tag="KNP54_003527"
     CDS             complement(3116..5401)
                     /locus_tag="KNP54_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBF0894387.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHIKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLLYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYGKKYILEKCIKIDK"
     gene            complement(5398..6078)
                     /gene="pgmB"
                     /locus_tag="KNP54_003528"
     CDS             complement(5398..6078)
                     /gene="pgmB"
                     /locus_tag="KNP54_003528"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBF0894388.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            complement(6302..8185)
                     /locus_tag="KNP54_003529"
     CDS             complement(6302..8185)
                     /locus_tag="KNP54_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBF0894389.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            complement(8443..9264)
                     /locus_tag="KNP54_003530"
     CDS             complement(8443..9264)
                     /locus_tag="KNP54_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBF0894390.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            complement(9455..9808)
                     /locus_tag="KNP54_003531"
     CDS             complement(9455..9808)
                     /locus_tag="KNP54_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894391.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            complement(9850..11292)
                     /locus_tag="KNP54_003532"
     CDS             complement(9850..11292)
                     /locus_tag="KNP54_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBF0894392.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
BASE COUNT         3724 a         1956 c         1054 g         4719 t
ORIGIN      
        1 tcatttatat atatgataaa tatatcaata tctattttcc tttaaccaaa tgctatttta
       61 ataagtttaa gttttagctt taaaatactt aataatacaa taaaagtgat gtatttacaa
      121 ataattcttc tggatttaat tcatttattg atgtatgttc aatttttata tttatatttt
      181 tcatatcttc ataaataatt ccaactggag aacaaatgaa acaagaaaat ccaaaagttt
      241 ttgttatttt ttttacctta ttatcaccaa aacttatttg ctttttacaa tcgtttatat
      301 tttcattgtt attttgtata tcatttttat aatacttatc ttttttaatg tcattagact
      361 tatttactgt tttaaaatta ctcctatttt tacaactata gtctatttca acttctatat
      421 acccaaaaac tatcaagtta cataatttca aattactacc tttgtttata agatttttca
      481 taggtttaac atcaaatatt ttactattta catttacttt taatatatct cttagatttt
      541 taggagcttt taaagtatta cttatattca attgtttgaa tacaatttta tttacattag
      601 tataaactct attactttct attgatattc ttgttgggaa tttatctaga ttacacttat
      661 aataatagta tatattagca ctattcttta taatcctatg tgcagaattt ggtaaaacta
      721 cactcttaaa agatattatt tttttacaac ttgcatctat tctccctatg taaaaacctt
      781 gctgtgggtc taatccacgt tttataatgc cattaacttt taccgtatta tttataaact
      841 ctatatattt agaaatataa tctttgaaaa atatatttcc agttttgtac ctacttgtat
      901 ttgtaacaat aatagtgtag gtcaaaatct caaatacaga tgcacatttt ttatcaacat
      961 atttttctac ttttataata cttccatttg catcatttga aaatacatca ttaaaagtag
     1021 ttttcgttat tctcattgca tccacctttc tataatttaa agattactct atcttggaac
     1081 tattttcata acttataatt gcagtaacac taataaataa attatcatct aaaatagatg
     1141 aagtaatatc ttgtataaga tactttaaat taattttatc tttattttct atctttctag
     1201 gcatttgtat aaatgtacta aagggtattt ttaatttaaa tgtatttttt ttactagaat
     1261 ttctatttct tttattgcct gcataatcta atattgcatc aatatctata tcaccaacta
     1321 aaatcaactt ctttcctgta agttgttcat cttctaatga tatacattct atagtatcaa
     1381 caagacttat attgttaata ttcatattgt aaacatatgt ctctaatgaa tttattacag
     1441 tttttttaga agctaattta aaatttttat atgtattaaa ttgagataaa taaagagtct
     1501 tttctagttt ttcacatctt tcaaggttgt atattacctt attattttca tacataatcg
     1561 catcaatctc cctgtatcta tatattaata ctattcataa aaattatttc aaattaccat
     1621 tttttattat tcactatcta gttgttattt acttttaaga aagaatcctt ttttacttca
     1681 ttgatttcaa tttacaagta aaagtctttc tgaaaaaaaa atatatatat ctctattcac
     1741 ttttttataa gtaattataa tttttataga ctaacggtca gccttaaggg aaaaggtgtt
     1801 ctttaagtgc agaatttaga taaagtaaat aatcctttta taaataattc caagttttaa
     1861 cttaaataat ttgatttaca gtataaagta aattttgaaa gataatgata tcgatttaat
     1921 aattacaagt aaaagcatgt caaaataagg ctatgatttt aaaaatcata gccttatcaa
     1981 taaaaattta atcaaagtta catttcactt tgaatttcac tgtctattaa ttgaagatta
     2041 tactgttgaa ttaattctat tagacgagct gcatatatac tattgccatt ttcatccttc
     2101 gcagtactat aacctgcctt ttctaatgct ttagcttgat atatatacgt ttttgcatca
     2161 aatacaccat tgtttttata ccttttattt gtggctaaaa attttgcatg gtcttttata
     2221 gattcatttt tatcatcata tattctaaat ttatcatcta taattgtatc taaatgttct
     2281 ttcgtttcta aagtcactga cttgcctttc caataagcgt cagcctttat accaaataga
     2341 ttgttatatt gttttgccaa agttgacttg ccccagctag attctattat agcttgtgca
     2401 atagttatag atggaagtat tttataatcc ttataatttt gtattgcttc tgttttaatt
     2461 tcatcaataa acttcatata ttttgtatca gacttcaatc tttctggttt tataccataa
     2521 tccttaagat tgtctatata attatcaacc aatctttttt gtctattact aaattctaac
     2581 tcatccaaaa tatcacttaa cttatttatt ttattatttt tagaaaaatt cttaacaaat
     2641 aaatctgata cttcttgtat ctgtgaatcc ttaacgtttt ttaagttatt tttatttaac
     2701 acagcaacaa tggaagctac atacttccag ttaacttgtg cattattttt acttgctaaa
     2761 tcagcatatt ttatatactt actgacattt atatcatcct tttttatctc tctagatgaa
     2821 tattccttca ctaatacacc tattaaaatt gatattatca gtattataac aatgaatttt
     2881 ttattcttca taaatattgt cctcccttat actatctgct gaatataata taccttactt
     2941 ttgtgacata ttctttacga aattttgaaa attttatgaa gatttatgaa atatatttaa
     3001 ttaaaagcac tactattgtt ataatatata gttttctatc acacaaaata gttaaaataa
     3061 ataaataatt agatagctta ttttaactat ttatataata aaaatattat taaatctatt
     3121 tatcaatttt tatacatttt tctaatatat attttttccc atatacaata atttttattg
     3181 gtttaccttt taaattttct attttaatta aatcactaca tacatctaca ttaataatat
     3241 tatctctata atttatattg aaagaataat ttttccactc ttttggcaac ttagggtcaa
     3301 aagatagagt ttcattccat gttctcatgc ctgcaaatcc atgtacaatg gaaagccatg
     3361 aaccagacat tgaagttatg tgcagtccat catttgtatc attattgtaa ttatctaaat
     3421 caagcctagc tgttcttgaa tataattcat aagccttttc taggttatct atttctgagg
     3481 caataataga ataaatacta gaagataaag aagattcatg tacagtatat ttttcataga
     3541 agtcaaaatt tctctttttt tcttctttag taaatctatt tccaaaatag taaattccct
     3601 gtaatacatc tgcttgtttt ataaaacacg acctaagaat cttatcccaa gaccaatttt
     3661 gattaagagg aaaattttct tttggtaaat cctttacttc tacaaattct ttatctaaaa
     3721 aattatcatt ttgaattatt atttgtagtt cctcatcata cagcagatac attttatttg
     3781 atattatttt ccaaaactca acttcttccc tagtcacatt atttctgtca atacattcat
     3841 tacactcttt ctctaatcgt aagatatttt ctacagcata atctaaacac catttagcta
     3901 tataattagt ataccaatta ttattgatat tgttttcata ctcgtttgga cctgttactc
     3961 catgtatcat atacaaatct ttttttgtag acaaatgaac tctacttgcc caaaatctag
     4021 ctatttctat tattacatct attccttttt cttttatata tttatagtca cctgtataat
     4081 ttgtatagtt atatattgca tatactatac ttccatttcg gtggatttcc tcaaatgtta
     4141 tctcccattc attatgacat tctactccat caaatgttac cattggatat aaagcacctt
     4201 taagacctag tttttttgca ttatcctttg cctgttctaa ctgattgtac ctatattcta
     4261 aaagatttct agttacctcc ttatctgcta cacctagata tactggaaca caaaacgctt
     4321 ctgtatccca ataagtagct cctccatact tttcaccagt aaatcctttt ggacctatat
     4381 ttaatcgcga atcttctcca taatatgttg aaaatagttg gaataaatta tatcttatac
     4441 cttgttggct acttttatct ccatttattt ttacatctgc actttcccat cttttattcc
     4501 ataactttat atgttcattt aatatatcat cataactttt agatagttct ctatttaaaa
     4561 tgtcttcaca ttttcttaat agctcacttt ccttataatc tctagttgag gttatagata
     4621 catatttttc tatacttgca acctcatttt ttaaaacatc cattgttatc gaattttcac
     4681 agtaattata atcactctca tgagatacag cttctacatc accatttgtc ttaatataca
     4741 tcattgaacc cacagtgaat actggtgtat taaatgcatt ctcctttgtt cgagaaagaa
     4801 tactcccttt atattctaaa gaacttgaag aaattccatt ccaaaacttt tcctcatagt
     4861 ttgaatcttc attttttata tttgaatcta aatatggtac aaattttatt ttagtattag
     4921 aatttaatga ttttatactg tatttaatta ctgcaagttc cttaacagat atacttaaaa
     4981 acctagtaac cctaacttca aattttttat catttatatt tacaataaac ctacgattta
     5041 aaataccatt tttcatatct aattctctat gaaaatcttc tactttacat tttgctaaat
     5101 ctaattctac atcatctatg aaaattctta cacctatata gttgactgaa ttaggaattt
     5161 taccaaagta ttctggatac ccatttttcc accaaccaac acgagtttta tctggaaacc
     5221 atactccagc tatataagac cccttgtgtg tatctccact ataattttcc tcatagtttc
     5281 ctctcatacc catatatcca ttgcctatac tcattatgga ctctgctaat ctattttctt
     5341 tgatttcaat cttatcttgt ataatcttcc actcatctac attactaaat aaacatttca
     5401 tataattctc ctaactatat actcattata cttttcttgt atatattcaa actttaattg
     5461 atttgttgaa tctacaacta aatttgcttt ttttaagttt tcataatttc caacaccaac
     5521 agaaaacata ttagctgagt ttatagcgtc tatacctgca cttgcatcct ctatccctat
     5581 gcaattttgt ggatttacat taagcccttt cgctgacata agaaatatct ctggatgtgg
     5641 tttattgttt ttacattttc ctgcatcagc tataaaatca aatttgtcac ttatacccaa
     5701 atgatttaat acatttattg cattcttact tgcagaagat agacctatct ttatattatt
     5761 agattttaca tcaattaaca agctttctat gcctggcaaa atatcatttg aagttatctc
     5821 atctatcaat gatacatagt aattattttt ttcttcagcc attctcactt tttcttcttc
     5881 tgaaaatgaa tatttcttat ttccaaattc taatatcctg tccaatgact ccattctact
     5941 tatgcctttt aaagattcat taaattttgt gtctatatct atcccaactt tatgagctag
     6001 ttttctccaa gccatatagt gataatatgc agtatctgta attacaccat ctaaatcaaa
     6061 tataaatgct tcaatcattc ttatttcctc tttctacaag aaatttttag actaataatc
     6121 aatttatttt ctatcttgta tttaagatat tatttataaa attatctact ctaactcagt
     6181 ctttaattta aaatctactt tcaattcact cacttgtaga ccatattttt tatcgtttat
     6241 aaagacttgt ttaaactgta taataattta acatgaaatc taaaataaat acttttttgt
     6301 attattttaa aataatgaac ttgtatttct ctaacattag ttcttctttt aaatcaacta
     6361 tttcttcttc atataaatct tttacttttt tatttgctaa ataatctggt aacgtcaaaa
     6421 ttatattttt agatgaatta tttattatta tagaaataga ttcttttttc aatataatcg
     6481 ttccattttc cttatctgct aacacccatt catttgatat agacctaagt tctttatttt
     6541 ctttacgaag tctaataatc ttcttcataa aatcaaatat atccttattc catttttctt
     6601 cattccattc catacatttt ctttgacctt cagatattga acttaattct ccttccattc
     6661 cgatttcatc accatagtat atacaaggac atcctgtttg tacaaacata aacatatatg
     6721 caagtttaaa tctatcaata tttccattag cataagtcaa tattcttgta gtatcgtgac
     6781 ttccaagtaa attaaaaata acttcactaa cttgtattgg ataacttacc attacatcat
     6841 ttatcatata cttaaattct tcggcgttta tctcatctgt acaaaagaat tttttcatgg
     6901 cttctgacat caagtaattc ataactgaat caaattggtc acccattaac catggtaaac
     6961 taccatgcca aatttctccc aatatataaa tgtctggttt tacttttttg acttcttctc
     7021 taaactttct ccaaaaaaca tggtctactt catttgaaac atctaatctc cacgcatcta
     7081 tatcaaattc ctgtatccag tacttgccta catccaataa atattttatt acttctgaat
     7141 tttctgtatt aagtttaggc atatattttt cacacccaaa ggtttcataa ggtatatttt
     7201 tttcatctat ttgttctatt ggagtatcaa ttttactcat atcttttata taaaaccagt
     7261 ttttatatcg agaattttcc ttattttgaa ctacatcttg ccactgttta gaataatatc
     7321 ctatatgatt aaaaacagca tccaacatta tttttatatt tctcttatgc gcttcttcta
     7381 ttagtttttt taaagtctct ttatctccta atgtagggtc tacctccata taatctaccg
     7441 tatcatatct atgattggtt tttccaattg taatagggca aaagtaaatt ccgtttattc
     7501 ccaaatcact caaataatct aagtgttcta tcacaccttg taaatctcca cctgtaaaat
     7561 tatctctggt tggaatagct ccccatttat ctactccttc tgggtttata gacgggtcac
     7621 catttgcaaa tctatctgga aatatctgat accaaacagt atctttcacc caatttggca
     7681 ctttaggtat atctatataa tttaaatatg gatatccaaa aaaattacct atttcacata
     7741 attccttttc atcattttca tttcccaact ctattattct tttttctgta aataaaagtt
     7801 tttcctcttg accttctatt ataaagccat atcgtgagcg tttatttaaa ggcttacact
     7861 tagctatcca atagtcaaat aattcagttt ctacttcttt actcattact atatttgttc
     7921 caccagacca accaactcca gatgcattta aatttcctcc tcctgcacct cctttatccc
     7981 acacatattg gtctcctatt cgtaaaatta ctcttttcgc ttcatttttt ttagttctaa
     8041 gtcttatatg tagtgtttct ctatcataac cataggcata attgctcatt ggtatatgta
     8101 atatagcttc ttttgttaaa ctattttgaa ttgttccttt gatttgatta cttaaagtta
     8161 tattttcttt atttttatta gacattttaa aatttccctc ctttataata atttatataa
     8221 tctaaagata ggttaatata ttttactatt atatcacaat aaaaatatat aatagtaaaa
     8281 tatatcaaca ataaactatt caatttaaaa taagctatac tatttaaatt taattctatt
     8341 tagttatttt agcaaaataa aaacctctag tatttttcta gaggatacaa tactataact
     8401 attaactttt taactatcta ttaatttact tcaaaacaca ctctaagcta tattgttaga
     8461 tttaactttt tctatattta caaaataggt ttctctttct ttaaataaag atacatattt
     8521 aaagtcaaga tacttaagca tatcataggc cacatcaaaa tctttgcata tatcttctac
     8581 cctatgagaa tcagaaccta cagtaactat aaatcctcca agttctttat atctttttag
     8641 aatatcttca tttggatgta tagcatttag tccatatcta taaccagaag tatttagctc
     8701 tataccactc ccattattga ttattgactt taagacctca tcaataacat ctttaaagtc
     8761 attgtatata actctattat ctgaatatat tccataccta gatatataat ccaaatgacc
     8821 atatatattg taatctccaa attcacgatt agtttcaagt atgctattaa aatatttata
     8881 atacgcatct tctttgctaa gacctttaaa atacgccttt gatggaacag gtacattgtc
     8941 aattgtatga gttgagcaca atacaaaatc aaaaggatta gaatttatta tttcttctat
     9001 ttcatttttt agatgttttc tgtaacccac ttcaacacct agtaataact ctatgtcctt
     9061 tttatatttt tctttaaact tattaaatac tggaacatag tcattataat ttatgcaaaa
     9121 tcctctatct tcatcatgtt ctaaatggtc tgtaaaagtc aaatatctaa caccaatact
     9181 tatagctttt tttattgtat cttccatgga atcctttcca tcacttgaaa aattagtatg
     9241 aatatgatta tctattaaat tcatattatc cctcccttta ttttatctat cttaattata
     9301 caacaagttt attgtataca tttgttaaaa gaaaattata atggttaaat tttatttaca
     9361 tacttttatt tttacaaaaa agagaagcac ctatttctga ttttagaaaa tcattaagga
     9421 tacttctcct aatgttactt ttatatactt caatttaatt tttaaaagtc ttaattttgt
     9481 aatagagttt agctgttata tgtccaatca tataaaaagc tgtataaagt aaaacatata
     9541 tatatgcaga atcatttaaa aatatataca ttaatactat ataagttact aaagaaacaa
     9601 taagagataa aatccaatta gtcttattta atacacaaat tatcccttgt atcaaaaaag
     9661 aaattggaaa aatcaaaacc attcccacaa caaaaatact tttagattga atatctggaa
     9721 tattaaatat atctgtagca aaagttaaaa acattagcac cattatgact gtaggaaata
     9781 tgatactaaa aatattactc tttttcataa taatcaatcc ttatttattg gatatttgat
     9841 aatcttcaat tattttgttg cctcaatttc tcccatcatt cttactaaat cttgtccata
     9901 ttgacctcca gcccaattat tagataaact ttcaactgtt ttagccttac caaataaaga
     9961 tttttcatgt ctagggtcta ctggatttga aagtgggtaa ccatcttgtc ctgcatataa
    10021 gcataaatgt tgaatttgag ctaatattcc ttcttcccaa gtatcaaatc ttgaatgggc
    10081 attcttatca gtatcagaac cacctacaga agttttaagt ccacaaggat tcttaaatga
    10141 tgcatctaat actccaccaa aattacaaaa accagtttct tttgcagatt gagctactgc
    10201 caaaacagga ttaacacctt cctgaacagc agtatcatat aatattggta ttaactctat
    10261 aaataaatca ttagcttttt tagattttgc ccattttaag cacgcttcta aactagctgt
    10321 tggctgacct aatatgcttg tctcattttt cataggtgac tcaccttttg tagacgaatc
    10381 gccattattt tgtgcagcag aaacacactt attatacaca ctgtcactta ttgaacctaa
    10441 tctagtaatc ttatctgctc ctgctaatat agacttatca ctactttctg acaccaatac
    10501 aattggattt tccttagcaa ttgtagaacc tgtaagtgca tttactaaat catatccatc
    10561 actcaaataa aattctgatg catctggata aaactctttt ataactttct tatttgtatc
    10621 atatctatct gaaccaccaa gtcttttagc attagtttta ttaactaaac tagtgctcat
    10681 tgatatactc ccacctactg catatgtttt tacattgctt gttgaaaaag gcacactctt
    10741 tccatctgta agtactatag gagctatatc tcttactgat acgggtgcag cacttattgt
    10801 atctgcttct cctttatatg cattagttaa tatcacttca tcaacttttt tgataccatt
    10861 tacctcttta gcaacactat aactagtctt tattctgtca tctccaccca atctagttac
    10921 ctgtgcccct gtgtttttta gttcagtttc tactgactta cttattgata attctttacc
    10981 tattatgtat atctttttaa cattttttaa tctttgtttt gtttcatttg gtatcttatt
    11041 tttttgtgca agcaaaattg gagcatcaac agcacctgca agaccacttg ctgaaagacc
    11101 atctgctata gaattatcca tatttaccat aattgctgta tcataactct ttttatctgc
    11161 tattaatcca gccgtctcat atatattgtt acctttaatt gtatctgatg ttaatgcatc
    11221 tacattaggt acatttatta gaaatatagc taatgttaaa cctaatgcta aaactcttct
    11281 aattgttctc atattcttcc cccttgatat atcaagttta attcaaaaat gactataaca
    11341 tagtattaca tctacgctat agtcatttat tataatttaa taattatata tttgttatta
    11401 tatcataaat tacaaaaagt ttccataata ttgtatagat taaaggaaaa att
//
LOCUS       DAEHWO010000107        11109 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEHWO010000107 DAEHWO010000000
VERSION     DAEHWO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11109
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.109"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            194..2206
                     /locus_tag="KNP54_003533"
     CDS             194..2206
                     /locus_tag="KNP54_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBF0894393.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            2575..3795
                     /locus_tag="KNP54_003534"
     CDS             2575..3795
                     /locus_tag="KNP54_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0894394.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKVDYIFGLHVMPHIETGFIEIKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3832..5181
                     /locus_tag="KNP54_003535"
     CDS             3832..5181
                     /locus_tag="KNP54_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBF0894395.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKFFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            5295..5857
                     /locus_tag="KNP54_003536"
                     /pseudo
     CDS             5295..5857
                     /locus_tag="KNP54_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5965..8298)
                     /locus_tag="KNP54_003537"
     CDS             complement(5965..8298)
                     /locus_tag="KNP54_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBF0894396.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSRLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(8295..8978)
                     /locus_tag="KNP54_003538"
     CDS             complement(8295..8978)
                     /locus_tag="KNP54_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894397.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            complement(9049..10290)
                     /locus_tag="KNP54_003539"
     CDS             complement(9049..10290)
                     /locus_tag="KNP54_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0894398.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            complement(10301..10987)
                     /locus_tag="KNP54_003540"
     CDS             complement(10301..10987)
                     /locus_tag="KNP54_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894399.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKNLLTVR
                     RMGYKWNVIK"
BASE COUNT         4102 a         1566 c         1448 g         3993 t
ORIGIN      
        1 tttaagtttt aagcaacaat tagggggatt tggtgacaag atttttaatt ataagaaaga
       61 aagtgtctta atgcaacttt tataaagtca ttatagacac tttctttttt atttgataaa
      121 tttaaattat caaaattata ttgctttata caactatttt gttggaaact atttattata
      181 taaggagaaa taaatgaaaa aatcagtagc tctggtaaat gatagtagaa aagatttaat
      241 agacttttta gaaaataatt tgaaattagt ttttggagat tctataaata ttaatagata
      301 cttcataaat gaaataaatg ataatgatat tataaatgat gatgtgatat tagtaatgtc
      361 agtagaaaga ttagacaaaa ttataaataa tatactagat aagaaaaaag tgattgtggt
      421 aagaagaact tttagggaag ataaaattta taatctacta tctttaccac agggtacaaa
      481 tgttctaatc gtaaatgatt ctgatgaaac tactctagaa actataagtt tattttataa
      541 aattggagtg actaatatta gaccaattcc atatatgaat gataataact ataaaaatat
      601 aaaaatagct ataactccag gagttccaga aaaagtacct agctttatct cagatatatt
      661 tgatttaggt cacagatata tagatatttc tacatttata gaaataataa atttattaca
      721 aattgattca aaggaaatac aatctaatct agttaaatac tcagaagaaa taataagttt
      781 agatactggt ataaaagata aatataagga attattttta aaaatagaag aattagatac
      841 aatattgaat ttatcaaaag atggtatatt atttacttca aaagatggtg aaataaatac
      901 atataatagt aaagtaaaag atattttaga cataaatgag gatatatatg gaaaatacat
      961 tgaggatata tttgtagata gtttaaaagt tttattgagt gagaaagaga tactagataa
     1021 agttgtcgta ttcaataaga aatatataaa tgtaaataaa aaaaacatat acaatagaga
     1081 tgaaaaaatg ggcacatatt atagtttaca agaaataaca tacataaaaa aattagaaca
     1141 aaatctcact aaaaaattaa gagaaaaagg acaaatagca aaatatacat ttaaggatat
     1201 aaaaacaaat agtcctaaaa tgtttgaatg tatagattta gctaagaagg tttctaaatc
     1261 tgacttaagc atacttatca gaggtgaaag tggaactggt aaagaactca tagctcagtc
     1321 tatacataac aactcaaata gaaaaaatca accctttata gcagtaaatt gtgcagccgt
     1381 tcctgaaaat ttattagaaa gccagctatt cggatatgac aagggaactt ttactggagg
     1441 tctaaaagat ggaaaacaag gattatttga acttgctaat aatggaacaa tattcttaga
     1501 tgaaataggc gatatgcctt tagaattaca aacaaaacta cttagagttc ttcaagaaaa
     1561 gcagataatg cctgttgggt ctcacaatgt aattaatata gatgttagaa tcatatctgc
     1621 tacaaataag aatttagaac aaatgattga taatagccaa tttagagagg atttatatta
     1681 tcgattaaat acaattccaa taaatatacc tcctctaaga gaaagaaaag aagacatatt
     1741 aattattatg gaagatttaa ttaataagaa attagtaatc acaccagaag caaaaaaact
     1801 tatacaaaac tatatgtgga aaggtaatat aagagaactc caaaatgtta catcctattt
     1861 aaacattatg tgtgaagata ttgtattaga gaaagattta cctccaaact taaggtcttc
     1921 agataacaaa aatacatcat taaaactaaa atatagtaag aatgatatat tgaatatatt
     1981 agagatacta attttaaata aggaatcaga tgttggtatt ggtagaggat taattttaaa
     2041 agcactactc gataagaacc ttcaaattac agaaggaaaa attaaaaaaa tatttgaata
     2101 tctaaaaaaa gaagaactta taatttgtag ttcaggaaga tatggaagta aaataactca
     2161 aaaaggagaa gatttttaca ataaattaaa atataaaggt ctataaaatt ataatttatc
     2221 aaacaaagaa atctattcag gattaaagta ctccttcaat aggttttttt atttttcaag
     2281 taccctgaaa ttataattta ttttgtacat aaataatagg aattaatagg aataggataa
     2341 tttttttatt tcctattttt tttatataaa ctagcatata aaatatattt tcttcaaaat
     2401 aatatttttt actgaaaatt gaaactatgc aatcattttt tatactatac atatagataa
     2461 atgattatat ttattcaata ttcttataaa aaacaaagtt ctccatcgaa aattatggca
     2521 taataattgc ttattatatt aataaaacaa taaaaagcaa ttggaggaat aaaaatgcaa
     2581 caggctttga aattaaaata tcaaaccaaa gaattaggaa aagattttgt aatagaaagt
     2641 tgtaattcta taaaaccatg gcttataaac ataagaagag aattacataa aattccagaa
     2701 ttagctcttg aagaaaatct tactaaacag aaggtaattt cttatttaaa agaaatcgga
     2761 attgattata tggaatttac aaaacacaat ggaattatgg catatatttt aaaagaaagt
     2821 gcagataaaa cgatttgtat aagagcagat atggatgctc ttcctattga agaagaaaac
     2881 aacatacctt ataaatcaat acattctgga aaaatgcatg cttgtggcca tgatgcacat
     2941 acaaccatgc tacttggagc atgtaaagtt ttacattcaa taaaagataa acttaatgta
     3001 aatgtaaaat tcttatttca accagcagaa gaaggttttg gaggagcaaa attcttagtt
     3061 gaagatggat gtttagaaaa tcctaaggtc gattatatat tcggacttca tgttatgcca
     3121 catatcgaaa caggatttat cgaaataaaa tatgatacat taaatgctag tgtagacact
     3181 ataaaaataa gtatcaaagg taaaagagct catggtgcat atcctgaaaa tggtattgat
     3241 gcaatagtta cagcttcaca aattgttaca tcattacaaa ctataataag tagaaactta
     3301 gaaccaaata atgctgctgt tttgactata ggtaaaatat atggtggtga tgcacacaat
     3361 gtaatatgtg aagatgtaaa actagaaggc actttaagaa ccttaaatag caaaacaaga
     3421 aactttatga ttgataaaat agctaaaatt gttggagaca ctgcatctgc atttggttgt
     3481 gttgggactt tacatgtaag tgatgaaaac tatcctgctg ttataaatga aaaagaatta
     3541 gtagatacag ttatatcaaa tactaaagaa ttacttggag aggaaaaatt tatattgaga
     3601 ccaaacccgt ctttaggtgg tgaagacttt tctttttaca cagaacattg taaaggagca
     3661 ttcttccatt taggatgtaa aaatgaggaa aagggcttaa tttcacctct tcatacctct
     3721 agctttaata tagatgaaga ttgtttacca ataggtgtta tgatgcatgt aatgaatact
     3781 ttgtatttta attagtacag taattaataa aagaatagga gataaattaa tatggaaaaa
     3841 gctaagaaat taggtctatt tagtatgata ttattaggga ttaatagcat aataggttca
     3901 ggtatattct tactaccagg taaagtttat aatctagcag gtcaaaacag tatgtttata
     3961 tacatttttg ctacactctt agttctatca atacttttat gttttgcaga agttggaagc
     4021 atgtttgata agaatggagg agcatatcta tactccaaaa aagcttttgg agattttata
     4081 ggatttgaag ttggtacaat gtcttgggtt attagaatta tatcatggtc tactctagca
     4141 gtaggatttg caacagcttt aggttcattt tggccagaat ctgccactga atacaaaggt
     4201 tatatagctg caatactcgt aacactactt tcaataaata gcttatttgg aattaaaagc
     4261 acaaagataa tgaataatgt aataactata gctaaattag taccattaat agtttttata
     4321 atagttggaa tattctttat aaaatttgta aatattgttc cttcaggaaa tgtagttaac
     4381 tctagtatgg gtccagccat tatattagta ttttacgcat ttaccggctt tgaatcattt
     4441 attgtggcaa gtggagaaat ggaaaatcct aaaaaaaatc ttccagtcgc attaataacc
     4501 acaatattta tatgtgcaat aatttatata ttaattcaaa ttgtctgtat gggtatactt
     4561 ggagatagac tatttgaaaa cagtattcca attgcagatg cttcaagtgt atttttaggc
     4621 aattatggta aatttttcat atctgtagca acattaatat ctatatttgg tataaatata
     4681 ggttcatcaa tagtaactcc taaatgtggt tcttctctag cagaagaagg ttctcttcct
     4741 gcatttatag gaaaaacaaa taaatatggt gctccatatg tagcaataat aatatcttta
     4801 atttgttgta taccacttgt gctaactgga agttttgaac aacttgcagt aatgagtgta
     4861 attgcaagat ttgctcagta cataccaact tgtttatcag taatagtttt aagaaaaaga
     4921 acagatgtta aggcctcttt taagattcca tttggtcctg ttataccaat ggtagctatt
     4981 ttaggtagct tatggttgtt acaacaagct tgggcagaag atatttcaaa acctataact
     5041 caaaatagag ttttaatagg attaggggca atgttgttaa tagctcctct atatatattt
     5101 atgaaaaaaa ataaggaaat cgagcataaa aataaatcag aagattctaa attatatatt
     5161 tcgagagaaa aaattcaata atattttaca aactatttaa aaattatttt tctaatacta
     5221 tagaaataat tagaaatgga gatgttacgt atctaaaagt agttgataac acggatattg
     5281 gtacttttat agatatggga cttacaaaag acatactagt tccttttaaa gctaagactt
     5341 atccattgtt tagagatgaa aaatatttat tctatatata cttggataaa agcggaagaa
     5401 tagctgctac tacagacata gattcatatt tagaaacaga ccatacttac aatgtaggag
     5461 atgttgtaaa tggagttgta tatggattcc aaaccaacaa ctctgctatg atatgtgttg
     5521 acaataaata tgctggtgta atccttcata atgaatactt tacagaatta aaagctgggg
     5581 atgttcttga aaatttacat gttataaaaa tatacgatga tggtaaatta ggactttctc
     5641 ctagaggaaa cagaaaagat gaacttgata ccttagaaaa taagatttta agctatttag
     5701 aaggttcaga tggatatatg agattcaatg ataaatctga tcctaaagat atttctatct
     5761 tatttaattc aagtaagaaa attttaaacg tgctcttgga gtacttatga agaaagactt
     5821 aatttatcaa gatgaagatg gaacttatct aaagtaaatt atataacaca aaaatcgaag
     5881 taaattatga aagatatttt ctatttcata tttacttcga ttttttattt aaattactac
     5941 ctctatttaa attactactt atatttattg tgcatttact acctctatta tgtctaattc
     6001 acaaatcttt ttaattggtt ttcttactgc aagcaaagtt attattatca tagttactac
     6061 aatgataaac agtaaatcaa aaggtatttg ccagtctata tggaatttta atgttactaa
     6121 ggatacaaat atatatctat gtaatattaa tccaagtaca ctccccaata aacagccact
     6181 tacagcatat gtacttgatt ctactattac catttttctt aattgcttat tggacatgcc
     6241 tattgcacgc ataataccat agtaatttat tctacttgta acgcttatat tcatactgtt
     6301 tatgatatta aacatactta taatcgcaat tataaataca aacccatata caaaaactgc
     6361 catagtgtaa aatgaatttt tagcctctaa gttaccttgt cgcttatctc gaacctctaa
     6421 attatcatct agaacatttc ttatattttg gattaaatct tcaggagcat cttcatcaac
     6481 ttgagtatca attattatat agtcttttat atctgttata ctagtaaaag tattttcaga
     6541 tgttataata tttccaatat atttgtcttt aacatcaaat gaaattgaag aaagtatacc
     6601 tgctacctct atctctttct tagaatttcc atttttaata tatatcttat ctccaatatt
     6661 aaacccatga ccttcttcta ccaatccgat attttctgac tctaatttat cttcattgat
     6721 ttcccctttt actagatact ttttggccca gtcaaattga tttttttcat aagaaattag
     6781 ctgagatgtt gcctccttat tattgtatgt agcctctaca tccgtcatca ttctactgta
     6841 tacttttttt attcctttga tattacttat ttcattaata tcgtctttag taagaacaga
     6901 cttaaagtca gcgtcaacaa tagatatatg agcagcttct ggttttatag gtttaagtgc
     6961 ctgatacata aagtctataa atacactaaa acctaaaaac aatacaatac taatagcaaa
     7021 tgaagaagtc ataagtataa aagatttttt tcttgaaaag gcatgattta ttcccataga
     7081 aacatcaatt ttagaacttc ctgcgttagc aattttactt gcttttccac tagttaaaat
     7141 ttctttgaac attagattac cacgtatagc acttagtgga gacaccccag aagctttttt
     7201 tgctggaaca atagctgata atattactgt taaaaatcct actattattc caaacacaat
     7261 accaataaag ctaaccttta aaattggcat cgaaccaaat aactctgtat tcacatattt
     7321 gagaaatata gaggatataa tggttacaat acatcctaat aacaatccta gtggaatagc
     7381 ctttacactt agaattaaac tttctaaaac aacaaatttt ttgacttgga gttttgatgc
     7441 tcccaagcaa cgtaatagtc caaaaaactt tattctctct attacaccca tattaaagct
     7501 attatatatc atgataatac ttgctattaa cacaagtata aaaagtcctc ctgctgttaa
     7561 gtaaagtggt ttagaataat cagagtcacc ttgacctata atagaaagta atttttcatt
     7621 tttaccgatt tgtttatcac ttaaattgaa ggtattctta atatcagaag tagcttttct
     7681 aatattaacc ttgtctttaa atgtaatata ataataatca tatgtttctg attttttgat
     7741 agcttgtgta cctaatattg aaagcattaa tccatgctta tctgaggctc ttaatcttga
     7801 taatgatgaa tattcaccta ctatcttata atttttattt ctaccatctg ctaattttat
     7861 tttgataaaa tctcctactt ttagattaaa gcttttaact gcatctacat ctattaaagt
     7921 ctcattctcc acaacaggat aacgaccttt tattatttct agacctaatt gttttgctaa
     7981 atcttcatct aaaccttgta tcaaaatctc ctttgattta aactctccat tatcaatgac
     8041 ttgtcctcta ccatagtgag ctatatctac tctactactt atttctgata tagcttcttc
     8101 attaagattt ttaagtacta tgtgccaatt tccatcatct tttataaatt gtactttttg
     8161 acattgtata gccatgtctg ctagtccaaa aatagcagta actaaacata ctgcaatgac
     8221 aatacataaa attgtagttc tatttttttt cttatgtacc tttgcatatt gtggtactag
     8281 ttctaaatag cttctcattc tctattcacc cctaggtctt taagcattcc atcagaaacc
     8341 tgtagtatcc tatctgctgt agaagctata tttgtattat gagttatcat aataatagtt
     8401 tggttatatt tttctgctgt cacttttaaa agtgaaatta catcactgct atttttactg
     8461 tcaagatttc ctgttggctc atctgccaat ataattgatg gctttgtaat caatgctctt
     8521 ccaattgcaa ccctttgttg ctgaccacca gataattgat ttggaagatg actttttcta
     8581 tctttaagac ctaaaattgt caatacttca tctagataaa tagtgtctgg ttttttgtaa
     8641 tctagtagta aaggaaatat tatattttgt tccacagtta attcgggtat aagattatat
     8701 gattgaaaga taaaacctat attacgacgt cgaaaaatag tctgtttttc ttctttcatt
     8761 gaacatattt ctttaccatc aacaaatatt tttcctgagg ttggagtatc aagacctcct
     8821 aaaagattta ataatgtact cttacctgag ccagattctc caactacagt aacaaactct
     8881 ccctttgaaa ctgtaaatga tacatctttt aatgcctcta cttttgtata tccatttcca
     8941 tatgttttac ataaattatt aaccacaaga atatccattt gctctatctc ctttctgatg
     9001 attaatataa gaataattca tacaccttac tgtaagatgt atcctatctt acatattagt
     9061 aagctttaaa aaacttagag taaatgtact tccttgtaaa aaattacttt ctacagttat
     9121 ggttccattg tgctgttcta tgatagattt aactagtggc aaccctaatc caaggccttg
     9181 attacttttt gaaaacttac tcctataaaa tcttttaaat atatgatgta tatcttcaat
     9241 atgaattcca tttccggtat cactcactga aataatagtt gttataggtg tttcaaccca
     9301 ttctatcatt attttatcgt tctcttttgt attatctaat gcatttttta taaggttgct
     9361 taaagcttct gatatccatt cataatcgca aaacaagttt gtattttcta gacctcttat
     9421 agagatactc tttccttctt tttctgctct agtttcaaaa ctatataaaa ttttagtaat
     9481 caactttttt acgttaacac tagctttgtt aagaattatt gtctttgaat ctatctttgt
     9541 aatctttaac aagttttgta tcaatgattc tatacgctct aattcatttt gactcttctg
     9601 cacaaaattc tcaacaattt cactattatg actctcttcc tgcaatattt gattatacat
     9661 catcaatgct gtaagtggag tttttagttg atgtgatata tctgaaattg tatttttaag
     9721 aaattcttta ttctgctttt ctttcaatat atgtgtgttt agagatgttg acatagcatc
     9781 tattgaacca aataactttg ataaactacc ttcttcataa gtatttaacc gtacatttat
     9841 atttccattc ataaatgaat caattttata actagcttct tctatcttgt tctgttgcct
     9901 aaaaaaatac acatacaata taaaaataat catagtaaag aacacaaata aatacaaaaa
     9961 catagttttt atatatttac cttgaaacaa tttcacactt ggcataaaac tatcatctgt
    10021 accaaagtca tatctagctg tatttaagat ttcttttcct tttaaagtat atttatcttc
    10081 attagtagta aatactgctg gtatttttga tttatcaaca cccatactat ttaagtatcc
    10141 agctatatta taatcatgtt ctaacagtgc acttttataa tcattagtta tatttataac
    10201 tactatttga cctactacta taaacatcaa taaaacggat ataatcacca aaaaaaatat
    10261 ttttatgtct ttattagaaa ataccttcat attaacaccc tcactttata acattccatt
    10321 tgtaacccat tcttctaact gttaatagat tttttggatt ttcaggatta tcttcaatct
    10381 tatttcttaa ccttcttaca tatactgaca gagtattatc atctacaaaa ctaccatttc
    10441 catcccataa cttatccaat atattttttc ttgtaagtac aatattttta tttttcataa
    10501 gtaagcataa taatttatat tctgctgtag taagttcaag ctcaatttca tttttaaaaa
    10561 cacgattttc aagtaattta acagtaatat tatttgattt tagttcagtt acattttcac
    10621 ttgtaaaatt ataacgtcta agtaaagctt ttattcttga aattaactca tttaatttaa
    10681 aaggttttgt tatgtaatca tctccaccca tatcaagtcc catcactaca tttacttctt
    10741 catcagaagc agttaaaaat atgattggta cattagaagc ttctcttacc cttttacaaa
    10801 tatcaaaacc atcaccatca ggtaaggata catccaaaag cagtaaatca taattttttt
    10861 ctttataaat ttgcaatgct tcttctactg ttcttgctac atcaacacta aatccattct
    10921 tttgtataga atattctaat ccatatatca aacttaaatc atcttcaacc aacaatatac
    10981 tactcatctc aatcacttcc atttttttat tttttacttt atatatatta tatacctaac
    11041 ttattatatt tttactcttt taaaaataca ataccttgaa atcaatgatt taaatatttt
    11101 aaaattatt
//
LOCUS       DAEHWO010000108        11046 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEHWO010000108 DAEHWO010000000
VERSION     DAEHWO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11046
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.111"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(201..1097)
                     /locus_tag="KNP54_003541"
     CDS             complement(201..1097)
                     /locus_tag="KNP54_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0894400.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            1238..2665
                     /locus_tag="KNP54_003542"
     CDS             1238..2665
                     /locus_tag="KNP54_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0894401.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2861..5455)
                     /gene="clpB"
                     /locus_tag="KNP54_003543"
     CDS             complement(2861..5455)
                     /gene="clpB"
                     /locus_tag="KNP54_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBF0894402.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNNFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5492..6088)
                     /locus_tag="KNP54_003544"
     CDS             complement(5492..6088)
                     /locus_tag="KNP54_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894403.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNLDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6105..6509)
                     /locus_tag="KNP54_003545"
     CDS             complement(6105..6509)
                     /locus_tag="KNP54_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBF0894404.1"
                     /translation="MDKTLKKDLNQEYTESKSLIMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            6876..7250
                     /locus_tag="KNP54_003546"
     CDS             6876..7250
                     /locus_tag="KNP54_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0894405.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7247..8110
                     /locus_tag="KNP54_003547"
     CDS             7247..8110
                     /locus_tag="KNP54_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894406.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8110..8748
                     /locus_tag="KNP54_003548"
     CDS             8110..8748
                     /locus_tag="KNP54_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBF0894407.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            9240..9653
                     /locus_tag="KNP54_003549"
     CDS             9240..9653
                     /locus_tag="KNP54_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0894408.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            9844..>11046
                     /locus_tag="KNP54_003550"
     CDS             9844..>11046
                     /locus_tag="KNP54_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBF0894409.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDN"
BASE COUNT         3799 a         1545 c         1356 g         4346 t
ORIGIN      
        1 ttttttctgc tattcttatt tttccaattt tagtttcata ttaaaatata cttttcatag
       61 acactacatt ctttcatact cattttcaca tttaactata caagtagtct tactcattta
      121 tgtactatac tttattaata tttattaaga aaaactcaaa gatttaaaaa tatatatttt
      181 ctataaagta tatttatgaa ttatttcata tcttctttta aaataacatt actaacttct
      241 ttatgttcat ttctatactt agttggagat atattataat tccttttaaa taagcgacta
      301 aaataattta tgctatcaaa gccacatctc atagcaattt ctgtcatatt taaatctgtt
      361 tcctttaaat aatatatagc tttatcaagc ctgattccat ttataaaatc gattgtagtc
      421 ttacctgtta tttgcttaaa tgttctacaa aagtgatgtg cactcaagtt cacatgacta
      481 gcaagttctt ttaatgtaat tttatccata tatttttctt ctatcaaatc aaagatacat
      541 tcaaattttt ctaaagaata ctttcttttt ataaattcat cttcagaata tattttatca
      601 atatgacttc ttaataagag tactattaat tgatagatat tagcttttat agataactca
      661 tatccaactt ctttattgtg atattcatca agtatagttg taatacattt taaaatcaga
      721 gaatcatttt gaattaaatt attaaataca atatgattta aagccaatgg tgctaagtac
      781 ttggtttgta acaaatcaac ttgattacta aaaaggaatg tgggttcaat acgaatacta
      841 tagaatttta aattatctga taagctttct aaataatgta attcattact gtttgctatt
      901 acaatatttc caggcactac cttaaaatta tccaatccac attcaagata tgctatacca
      961 tcaataaaat aatatatttg tagatgctca tgccaatgtc ttttaaagtt tgctcctttt
     1021 ttaatgtcat cctttaaaaa aatatctata aagttttctt gacctttcct gttaaaatat
     1081 gtatttttat ccttcattat tcccccctca tcaaaatagt gctaattata agcaatatag
     1141 ttattgtatt cattatttca tatcgctatt atataaaatg taactatcat tgtaaacatt
     1201 aacataatgc agtcattata ataaggaggt aataaaaatg acaaactctt ttaaaaaaga
     1261 tgataataga aaaaaaatca cagttttatt tgtagtcatt gccatgactt ttatggcaac
     1321 attagattct agtattataa atgttgctct cccagttctt gcaagcaaac taaatgtatc
     1381 tctagcatct attgaatggg taatagcaag ttactcaatt attatttgtt caacactatt
     1441 attttttgga agacttggag atattattgg taaatcaaga gtatttcaag taggtactat
     1501 tctctttaca tcagcttcat tactatgtgg attaagtaat tctttaactt tacttatagt
     1561 ttgccgcttt attcaaggaa taggcgcttc tgcctacatg gcaaacaatc atggaattat
     1621 cacagaacta tttccaaaag aaagcagagg aaaagcccta gggattttag ttactgcagt
     1681 tgctattgga aatatggttg gaccatctgt gggaggattt attttgtcaa tatttgattg
     1741 gaatgttata ttttttataa atattccaat cggtcttatt gtaatctttt taaatacaaa
     1801 atttcttcct aatagtaaaa aatcttcaga aaatatggat aaaactggtg ctatacttca
     1861 atttttagga acaacattat tttttagtgc tctaattagt gctcaacaaa caggattact
     1921 aaatccatat atattaattg cactattatt atcaattatt tttattatat tatttttgat
     1981 attagaaaaa aaacatcctc aaccgcttct tgaccttgaa atttttagaa attttaaatt
     2041 ttcattgaat ttaatttgtg ctcttacatc attcatttgt attgcatcat caagtatttt
     2101 aattccattt tatttacaaa gtactatgaa acttccccct attcaagcag gtttatttat
     2161 gatactatca cctttgattt tagccatttt ttcacctata tttgggaata tatcagataa
     2221 aattaagtca gaaaaaatta ttttaattgg tcttctcgtt atgagttttg gattctttct
     2281 aatgtcaaga ttgaaagaaa gttctgccct tattttattt gtaatttata tatcgataat
     2341 atcaatagga caagctatat ttcaacctgc taacaatgct ttgataatgt caagctgttc
     2401 tagaagtaag ctaggagttg taggaagcat aaattccctt gtaagaaatt taggacaagt
     2461 tataggtatt actatttcta caacactttt atataatttt atgagtatta aagctggata
     2521 tagggtcaat gattatgtga ttaataatga taaaatattt gtatttggaa tgagaaatgt
     2581 ttatattatt gttacacttg tttgcttaat aggtgcaata ttaattggct tttatttatt
     2641 taaatataat aaaaatgaac aatagttttt ataattatat tcaaattatg attatattat
     2701 aagaaattta ctaaaatact tcctttgagt taaatttaat ttggacatat tgacttaaaa
     2761 atgttttatt aatttgataa aatatttctt ttcctatagt ttataaataa aaatcagctg
     2821 agcaaaatat ttagtatatt atgctcaact gattctttta ttatttaact aaaacttcaa
     2881 tattttcatc ttttccatct ataactatag tacatccatt atacacatct ccagcaataa
     2941 gtttctttgc aattatagtt tctaatgtat ttcctatata tctcttaaga ggtcttgctc
     3001 catatacagg gtcatatcct tctctcacca taacatcttt tgctgaattt gtaacttcaa
     3061 tagtaatatc tttttctttt aatctatttt ttaaatcttt cataaatata tctataattt
     3121 tcttgatatt ttcttggtct aaaggcttaa acattataat atcatctact ctgtttaaaa
     3181 actcaggttt aaatctatgc ttcatttcat tcattactaa attgttagta gtctctgtta
     3241 tatttcctcc tgcttctaat agataattac ttcctatatt agaagtcatt attataagag
     3301 tatttttaaa gtctactgtc ttacctttat tatcagtaag tctaccatca tctaatatct
     3361 gtaagaacat gttaaataca tcctcatgtg ctttttctat ctcatcaaat agtattacag
     3421 aataaggagc acgtctaact gcttctgtaa gttgaccacc ctcttcatat cccacgtacc
     3481 ctggaggagg tccaactagt cttgatacag catgtttttc catgtattca gacatatcta
     3541 ttcttattat attatcttca ctatcgaata aatttctagc aagagttttt gcaagttcag
     3601 ttttaccaac acctgtaggg cctaagaaaa taaatgaacc aattggtttt ctttcatctt
     3661 ttaatcctgc tcttgcacgt attactgcat ttgaaactgc tgtaactgct tcatcttgtc
     3721 caataactct tttatgaagt tcatcttcta gtttaagtaa tttttctctt tctccttcaa
     3781 ctagtttagt tactggtata cctgtccact ttgatacaat gctagatatt tcttcttcag
     3841 taacttcttc ttttaaaaga gaattttcag aaccatcatt catattttct tcgtactgct
     3901 ttatttgttc ttctaactta ggtatttcac catatttaac ctctgctgct ttgttgaaat
     3961 catattctct ttcatacttt tcagctttac ctttagcttc gtctaattga gcctttaagt
     4021 ttttaatatc taatatttga ctcttttctt tttcatattt tgctgtcatt tcatcatttt
     4081 tagattttaa ctctgctatt tctttttgaa tatcatccaa tcttgattta cttttatcat
     4141 cattttcttt aagtaatgct tctctttcag tttctaatgt aaataacttt cttctaacaa
     4201 catctaattc tgttggcaat gaatctattt cactacgaat catagctcca gcttcatcaa
     4261 ttaaatcaat tgctttatct ggtaaaaatc tatcttgtat atatctatga gaaagttttg
     4321 ctgctgctac aatagcatta tcatgtattc ttactccatg atgtatctca aatctttctt
     4381 ttaaacctct aagtatagat attgtatctt caacagtagg ttcttctgca attacaggct
     4441 gaaaacgtct ttcaagagcc ttatcttttt ctatatactt tctatattca tcaaaagtag
     4501 ttgcaccaat acagttcaat tcacctcttg caagcatagg tttaataaga ttacctgcat
     4561 ccattgaacc ttctgtttta ccagctccaa caatagtatg aatctcatct ataaacagta
     4621 taatttttcc atcagaactt tgaacttctt ttaaaactgc ctttaatctt tcttcaaatt
     4681 cacctctata ttttgcacca gcaattaaag ctcccatatc aagtgagaat acaatcttat
     4741 cttttaaacc ttctgggaca tctcctctta ctattctctc tgctaaccct tctacaattg
     4801 cagttttacc tacacctggc tcaccaatca atacaggatt attttttgtt cttcttgata
     4861 aaattcttat aatccttctt atttcttcat ctctcccaat tacagggtct aatttatttt
     4921 tcttggctaa atctactaaa tttgttccat atctagcaag tgcatcatat gtgccttctg
     4981 ggtcttgtgt ttctactctt tgactacctc tcacttgtga taaaatattt aaaaagttat
     5041 tcttatttat attatattgt tttaatattt taccaacagc tgattttgat tctgtttcca
     5101 tcattgcaag cataacatgc tctacactta tatatgaatc tttaaattct ttagaaatac
     5161 tctctgcctt tataagcacc tcatttattt ttctagtagc tgatactcct tgtgagtcag
     5221 caccttctcc atataccttt ggaagcttat caatttcaaa gtttacagta tttctcaaag
     5281 aatcaattga tatattcatt ttttcgatta tatttggtat caatccatcc tcttgattaa
     5341 taagtgctga gaaaagatga attacatcta cttgttggtt atgatttttt actgcttcgt
     5401 tataagcctc atttaaactt ttttgaactc ttaaagtcat tttttctacg tccatataaa
     5461 tccctccatt ttaatattat atccaaataa attaaattct ctcatttata attattgatt
     5521 ttctaagctc taaaagacta tcaagtaaat tctcgttttt ttgtatatcg aaactcaatg
     5581 ttaaattaaa tgttccatct aaattaaaaa aatcgaatac ttcttttgat tttgctatta
     5641 aatacaagtc ttcatctata agtctttttt cacctattaa taaatactga catttatcta
     5701 taaaactctt tttaaaatca atagtgtata gattttctaa aatattatat tgataaatag
     5761 caatattatt aaacactttt aatatgtttg aatttacaaa attgtaaatt tgattattgt
     5821 tatacagtga tatttgttcg tatatatatt ccctaaataa aggatgaatg ttttgcttaa
     5881 gttttaaagt aacttcagct ggtatttcaa aataaagctt ccagtactta gagttatttt
     5941 tttctaaaat aaaagctact ttgttcaaac tggtagaact aatctccttt agtgtacaat
     6001 taaaattata gtgtctcaaa ctagtttttt cattctcaaa tacatagtca aaccactgta
     6061 gaacatttct atcaagtttt aaactcatat aaaaaccttc ttccttattt actaacctta
     6121 ttaggtcttt ttatctgatt atattctgct aataaacttt ctttatcagc tctactacct
     6181 ttatatgcta tatgtggatt tatcatatac tcaccatttt tcactctttg taaaaaatcc
     6241 atttttttca gctccgtaaa caatgaagat aaagaagttt ttggatattc aaattcacaa
     6301 gataattcat ataatgtttt tctaatctta ttatttttat ccatagagtt tattaatttt
     6361 aatggaatta aatccctctt agtatacatt ccttctacta ctttaatata attcttaaaa
     6421 caaacattca tatacttact tttattcata attaaacttt tgctctctgt atattcctga
     6481 tttaaatcct tttttaatgt cttatccaaa ttaaatatct cttctcactc tccttatctc
     6541 taattgataa tataaatata ttacaaaaaa atatgtatgt caaaactgaa aatgcaaaaa
     6601 gttcacctta taagtaaact tttatttagc tataagctaa actttattat ttttttaatt
     6661 tagtatttcc aatttattgg caggattttt gaacaatatt tataaatttt ttaaaaaaat
     6721 ttaaatctat ttaatatggc agactttcat aaaatacatt acatttatta aatgtataat
     6781 attggtaatt agttttttct aaaatcagtt gacatattat atatatattt atataatgtg
     6841 tatatactat atatacaatt taaggaggtg tcttattgaa tatagttatt agtaattcga
     6901 gtgggaagcc aatatatgaa cagattacta cacaaattaa aagtatgatt ataagtggag
     6961 agttaccaga aggctcagct cttccaagta tgagactatt ggcaaaggaa cttagaataa
     7021 gtgtaattac tacaaaacga gcatatagcg atttagaacg agacggattt attgagacag
     7081 ttactggtaa aggcagtttt gtatctagta aaaacatgga ttttgtcaaa gaagaacaat
     7141 ttcgtttaat tgaagaatac ctacaaaaag cagttgatac agcaaaaagt agtgatatta
     7201 catatgacga attaaaagat attttatttt tattatataa aggagaatga taagtatgga
     7261 tgcaataact ataaaaaatt taaataaaac ttataaagat tttagcctac aagatatatc
     7321 tttttcagta ccaaaaggga gtgtaatggg atttgtaggt gaaaatggtg caggaaaaac
     7381 aactacatta aaagcaattt taaatttaat atcttatgat agtggaaata tagaaatctt
     7441 tggtcttgat agtaaaaaaa atgaaaaaga aattaaagag caaattgggg ttgtatttga
     7501 gggaagcaac tttcatgaaa atttaaacac tgaccatgtt tcaaaaatca tgagtaaaat
     7561 ctataaaaat tggaatgaca cattatttaa agactactta aaaaaattga gagtaccaga
     7621 caataaatta attaaggagt tttcaaaggg gaataagatg aaacttagta ttgctgtagc
     7681 cttatctcat aaaccaaaat tattaatact agatgaggca actagttcac ttgaccctat
     7741 cgttcgtgaa gaaatactag atatattttt agattttata caagatgaag aacactctat
     7801 tatcttatct tcacatatta caagtgattt agataagata gcagactata ttacatttat
     7861 acataaagga aaaattgtat ttagtgaaaa taaggatgaa ttaattgata ctatgggagt
     7921 tttaaaatgt aaacctagtg attttgataa cctttcaaga gaggattatt catattatcg
     7981 taaaagccaa tttggatatg aagtacttct taaagataag catagattta tctcaagaca
     8041 tccaaactgt attgttgata atacgtctat agaagaaatt atgttatttt atgtgagagg
     8101 tgataaataa tgaaaggtct aattttaaaa gatttactta atttgaaagg aaatataaag
     8161 tttatacttt tattcatcat tatgtttggc tttatgtctt ctttaggaga tggaaatgtt
     8221 aataacttta taggtgttat tatagtttta tgtactacaa tgattgtttc aacattttca
     8281 tatgatgatt tgaataaatg ggatagttat gtacttacaa tgcctattaa tcgcaatgat
     8341 attgtattaa gtaaatattt aactatgtta atatttagct ttataggtgt tcttgtttca
     8401 cttattgtta gtgtaactat tggttatttt aaaaatacac ttatattaaa tgaaacacta
     8461 cttattaatg cactaatctt atcaatttca gtatgttttg gtagccttat tctaccactt
     8521 atttataaat ttggtacaga aagagctcgt ttattaatga ttttatgctt tttagttcca
     8581 acactagctt tattagtttt taaaagtatt ttagaaaata ttagttcacc tatttctata
     8641 gaaattatac ttaatacact agtatattct cttccatttg ttgctatttt actatttgtg
     8701 atttcatatt ttatatcatc aaaaatctat agtaaaaaag aagtataaaa tatactatat
     8761 atgtttctgt atttaagtat ttaaataaaa tactatcgag tttattttgg tagtatttta
     8821 ttttttaatt attaatctct actaggtatt tattatttta ttacttatat ttaataagac
     8881 tatttactac tttctaatct tatttatata atttattcat tttataaatt gaactactaa
     8941 tgatattatt gaacatagca atagaataac atctaaaata gtttttatgt attaaattaa
     9001 cttattttaa tattcaacaa tttaggttta ctaaatttat tgatgatttc tttttatata
     9061 acttaaacta catttttatt taaaaaaatt taatatcaac aatataaaat taagaataag
     9121 tattattagt ttgacattag cataaatgcc tattagaata atgttaaact atattctttc
     9181 tactgatttt attaaaaaat accaatatac aaaagattat acaaggagaa agttcaaata
     9241 tggaattaga aattacagaa aaaatagaaa aacaagatga agatactatt tttcaaggat
     9301 tattaaaata taatcttgct agacttgaag ataaaaaccc agtggattta ggaatatata
     9361 ttcgagataa agcaggtaaa attgttgcag gttttatagg tgttactcat ggtaattggc
     9421 tttctataaa atacttatgg gttagtgaga agcttagata taaaggtact ggaagtcaac
     9481 ttttatataa ggctgaaaaa attgctaaag aacgaggttg taaatatgtt tttttagata
     9541 cattcagttt tcaagcacct aaattttatg agaaatttgg ataccataaa gtattttcac
     9601 ttgaaaatta tcctctaact ggaaagagat attattatag aaaaatacta taataataaa
     9661 aatcatattt catattttta aattaaaact tctgctcttc gtctacagac tttatgtttt
     9721 tatatcatta ttaatactaa aatagtattt tactatacat acaaaattat ttgaaagttc
     9781 aaaaattata agtataaaag ctaatcttag cttaaataaa aattatattt ttaggaggta
     9841 aatatgttag gaaaaaaatg tatggattat ctacaaacat taggaaaaat aagttcaaca
     9901 acaaatggtc ttacaagact tatcttgact caagaacata aaaaatctat tgatttaatt
     9961 agttcatgga tggaaggttt aaatcttgat attgaaattg atgacattgg aaacgttata
    10021 ggtacatata aatcaagctt tccaaatgct cccacattag tagttgcatc tcatcaagat
    10081 agtgtaaagt gtggaggtat atttgatggt atgttaggta taatagtgcc tctagttggt
    10141 cttgaagaag caaaacacaa taataggtct tatcctttca atattaagct aattgctttc
    10201 gctgaagagg aaggaactag atttgaaact tctttaatgg gaagtaaagt ttttgctggt
    10261 acttttaaag aggaacttct taaatctgtt gatgaaaatg gaattacact tgaagaagct
    10321 gtaacaaagt ttggatttaa tacaaaaaac ttaacaaatt tgcatcctag aaaagatgta
    10381 gatgcatatt tagaatttca tattgagcag ggtcctgttt tagaaaatga atctcttcct
    10441 gctggaattg tatcaagtat tacaggattt aaaagtttta agatatcagt aaatggtaag
    10501 tctggacatg ctggtacact tccaatgaat atgagacttg atgctggatg ttgtgcctgt
    10561 gaatgtgtat tagctatcga aaaagtagct aaaacgacta ctgatttggt tgctactgta
    10621 ggaaagatga atttctatcc atcttcatca aatgtggtac ctgaaagagc tgaatttaca
    10681 ctcgatgtac gctcttgttc acaagaaatt cttgataatt ctgtagaaaa gatatttaat
    10741 gaaatatcac atatatgtga aaatagaaaa cttaattata caagtgaact tgcttttgaa
    10801 aatgttcctg taccatgttc taataaaata acaaaaatca tagaaaaaag ttttatagat
    10861 ttaaatctta atccttttta tatttatagt ggtgctggcc atgatgctca ggaaatggat
    10921 aatataactg atattggtat ggtatttata agatgcgctg ggggcgtaag tcataatcct
    10981 aatgaaagtg tctctgtaga tgacttggat actgctgtaa aaatattttt aaaaatacta
    11041 gataat
//
LOCUS       DAEHWO010000109        11024 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.112, whole genome shotgun sequence.
ACCESSION   DAEHWO010000109 DAEHWO010000000
VERSION     DAEHWO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11024
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.112"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(<1..568)
                     /locus_tag="KNP54_003551"
     CDS             complement(<1..568)
                     /locus_tag="KNP54_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBF0894410.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDW"
     gene            complement(640..993)
                     /locus_tag="KNP54_003552"
     CDS             complement(640..993)
                     /locus_tag="KNP54_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBF0894411.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1071..1274)
                     /locus_tag="KNP54_003553"
     CDS             complement(1071..1274)
                     /locus_tag="KNP54_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBF0894412.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            complement(1664..1894)
                     /locus_tag="KNP54_003554"
     CDS             complement(1664..1894)
                     /locus_tag="KNP54_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0894413.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(1896..2303)
                     /locus_tag="KNP54_003555"
     CDS             complement(1896..2303)
                     /locus_tag="KNP54_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0894414.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            complement(2663..3112)
                     /locus_tag="KNP54_003556"
                     /pseudo
     CDS             complement(2663..3112)
                     /locus_tag="KNP54_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(3126..4052)
                     /locus_tag="KNP54_003557"
     CDS             complement(3126..4052)
                     /locus_tag="KNP54_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894415.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            complement(4177..4959)
                     /locus_tag="KNP54_003558"
     CDS             complement(4177..4959)
                     /locus_tag="KNP54_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBF0894416.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(5115..5735)
                     /locus_tag="KNP54_003559"
     CDS             complement(5115..5735)
                     /locus_tag="KNP54_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBF0894417.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5823..6521)
                     /locus_tag="KNP54_003560"
     CDS             complement(5823..6521)
                     /locus_tag="KNP54_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0894418.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            6622..7437
                     /locus_tag="KNP54_003561"
                     /pseudo
     CDS             6622..7437
                     /locus_tag="KNP54_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            8109..8876
                     /locus_tag="KNP54_003562"
     CDS             8109..8876
                     /locus_tag="KNP54_003562"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBF0894419.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9204..9881)
                     /locus_tag="KNP54_003563"
     CDS             complement(9204..9881)
                     /locus_tag="KNP54_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894420.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10031..10348)
                     /locus_tag="KNP54_003564"
     CDS             complement(10031..10348)
                     /locus_tag="KNP54_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894421.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10370..10708)
                     /locus_tag="KNP54_003565"
     CDS             complement(10370..10708)
                     /locus_tag="KNP54_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894422.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3661 a         1740 c         1565 g         4058 t
ORIGIN      
        1 gccaatccca ccatttaatt tctaataatt ttgaaattgt atcattatta aatctctttt
       61 ttataatttt tgcaggtact cctccaacaa tagaatacgg tggaacgtca ttagtaacta
      121 ctgctcttgt tccaataatt gcaccatcac caatatttac acctgacata attatagaat
      181 cataacctat ccacacatca tttccaatta taatgttacc cttattgtcc caagcgtccg
      241 ttatatggtt gatatcgagt ttccattctt cataaaagat gggaaaagta tatgtggatt
      301 ttgatttcat tgagtgattt ccactagtca ttagaaattt tgcattacat gctattgagc
      361 aaaacttacc aattattaat ttatcattgt ttatagggta atgatacaat acattgtttt
      421 tctcaaaatc tcttgggtca ttataaaagt cattatatat tgtgtaatct ccaacttcta
      481 tattttccct tgttattaca tttttaagat atacagtttg ataatcatta cttcttggat
      541 ataccttatt tgaacttgga atagtcatat ttaaatctct cctttaatat atattatgtt
      601 tttgactatt ccactactac aatacatctc ttcacagaat cactccttgt taagaatctt
      661 cataagataa tggcgtcctt ttttagtgtt aagtcggata ttctttctta gtccattctt
      721 tttagcgtat aactgacaaa ctgtcatttt cttaccaata gtgtcaatgc tatcatcaag
      781 gtcattttgt attgcttttt ccttatccct taatgatata tcatcacgtt ttccctttgg
      841 gggtttatca gtaggtacaa gtttccaaga gtaaacaaat tgtggtttac caaatgaata
      901 tacatactta tatgcgtatc ttccatcttt tctctggctc tctccagttc ttaaaattct
      961 atctttatta tctcgtcttt tttcagttga catgataaga agctcctctc aataaccgaa
     1021 ttgagcttga tacgtcatat gaatattata acatataagg ctcaatttca ttagataacg
     1081 tcaagtgtat caacgatttt ctcaaattgt tttctcttta tttgaatgcg attgctattc
     1141 ataatgaccc agccagaatc aaggttttca tcagcacgtt tacgtaattt tttctctcca
     1201 atacgaaagt attttgacgc ttcttcaatc gtcaaggtat atttttccca aataggtaca
     1261 tcagtattgt tcatataatg tatcactcct ttctatgttc gtagttcaga agtagataga
     1321 tggctttgat aagctccatt ggtatttcaa ccaatcccat tcttatggac agaaccgtgt
     1381 catacaggtg tatcattata ctgtggtaca ggttacggca aaacaaccgt tccaaaggtt
     1441 attcacaaat cactatatag tagctctctt gattaaggtc atggcgtata gtatttgttg
     1501 gctatctgta tcacaaacgt atctatctac tttattcagt tgtcaaagaa cagtcggcat
     1561 tgatttgcct ataaaaaatc acaatagctt gtgggctttt atagacaaat aattagtgat
     1621 tctccatgta ccaaatagct tgatacatgg agagagggcg agattaagac aaattaaatc
     1681 tcaaaatagc agtgattagt tttgttccta gcattcgctt tgtttcttct tctacatgaa
     1741 tatagggatt tccgtattca tcaaataaag ttttctgtga aagacgaatg atatagtgtt
     1801 caaaatgttt aagtattacg tttattgcat ttacatcgcc atgtacagca agtaaaataa
     1861 ttgtaaaagg taatacttct ttagtaggtt tcatttcaat gttcctgcat gagttctttc
     1921 aactctttta gtgcatttgt tttgtgataa tgtatggtat tttctgctaa atccatcaat
     1981 gttgctatgt cagcatttgt catgttgaaa aagaatgaaa gtagaattat atcttgtttt
     2041 ctttttgtaa gttttccgat tgcttgcgcc attaatacat cttcaattcg tatgttgtag
     2101 tcgtaagaaa ccatacagat gtagttagaa tcataatcat ctaaaatact caatttactt
     2161 aattctgcaa gtgacaaaga ttcgagagat accaaataat catttctgcg tttattttcg
     2221 tcataaatat ctctagcata gttacgcaaa actgttttac agaaactgtc gaattgatgt
     2281 tcaattgtct tttcatcaac cataagattt caccctcttt ccatcgcaag gagttaaata
     2341 accttgctta ctcctatcac ggtgggaggg cgttaaatct tcgataaatt tcaaaaaaaa
     2401 gagaaaaaaa tacacactct gcctataggg caaaaatgtg tattctttaa aacgtattta
     2461 atttatattg gttgtaagcc accaccatat tgatgtatgg aaatatgcat tggctagctt
     2521 ttcataaaaa tacaaagatg cataagaaat taatagaggg gaaaaactta ttctgttatt
     2581 aaaaagtagg ttaattctaa taaatgctat tgcggtcgaa ttaaactata tacatggcaa
     2641 tcaatcatgt ttctattctt tattatgaat tgtgacagta ttcttcaatc ttaaagccac
     2701 atttttccaa tactttactt gactctctat tgtaggaata tacattagca tgaattttgt
     2761 taaggttgta tttttcaaag gcaattttgc atatttcttt tactgcattt gttgctatcc
     2821 ctttgcctca atagttccta gcaagccagt aacctaattc agcattttta ttaatagagg
     2881 tatcttcttc aaatgttagg ctgatacttc caatagccct ttcttgataa aaaatagcat
     2941 agctaagttg tttaacatct gaagttgcca aacaaaaact aacaaaatct ctagcgtttt
     3001 gctccctata agggtggggg aagttgtcac gaagattctt tgcaatttct ttatcattcg
     3061 caaactcaac taaatcggta atataagcat aattccactc tataagttcc atttttcttc
     3121 tccttttatg aaacagctac aagaaatctt tctaagccaa taccacttat caaacagcgt
     3181 tctcttttat ttccaagcat ttgataagtc cagtcaacaa atccaccgtc aactatttca
     3241 acggtttcat ttccttgttt gaccgataat ttgaaattga tacctttata ataattatta
     3301 tcaacatcat cattatgaat tgataactct atattaggaa aaataagttt gatagtttca
     3361 accattctgt cgaaaaatcc gtcattatct ttgtatccgt ttcttttgcg tagaataata
     3421 gagaaacgaa cattttctat ttcacttaat atatctttat aatagtttaa gtgcttttct
     3481 aacaacattt tttcacaagt gtaagaccct gtatctatac cagatgaaac catacaatat
     3541 aagccaaaat gtgaatataa acctttacct acaaaatttt gtgctcttat taccctagca
     3601 gtagtagcca tgtggatagg tatggtatta ttttcttctt ttctttttaa tttatcagca
     3661 ataattattg ccaacatatt tgaggggtct gcaagtgttt ctgtccctcg tagagcactt
     3721 actacgttat attgatctac ggagccaaaa acgctacagc tacctaatgg ggcagaggga
     3781 gaaagcataa tcgtcttgat atccatattg aatgcttttc tcaataattt tgattccaaa
     3841 gcatgaattt cttctggatc tataccgcta gggatagtaa atctatttag ttggtatgac
     3901 tttagaatat cagttgcagt taaagtattt gcttgtctat caaacacttc taatagaagt
     3961 gagttcaaat ctgattttga tagagctgat aacttatcaa ctatattctt atccccaatt
     4021 ttatttgtaa ttctacttaa aatatcactc atagttatcc tccatactgt tactttcaaa
     4081 ataattatag aattgttaca acaactaatc taggtcattt gaccaaaaat gaaaaaacac
     4141 tgaatattta ctattcaata tttttttact ttgggtttat ttgattaaat cttgaaaata
     4201 ctgtaatgca accctttcag cttcaacctt tcggacaata ggactttgtg ataattcctc
     4261 tcttaactca agatacaggt tgatagtagc ctgcaatgca ttaacacagc ttttatattc
     4321 atggttagca accgtctttt ctaatgcttc aatatattgg ggtgcgtcca attcaatttt
     4381 tctaactcca cgaggtaatt tacctaagag aagctgtatt aatggggcaa gtactgattg
     4441 tcttaaaaaa gataaaaaat caattgtttc aaatagttct ctacgtccaa tcttagtgca
     4501 agcgtaatga acccaaatcc aaaatctatc ttcaatccac tgtaagtctg gagttgggaa
     4561 gtatgcttct tttttagaat aaatttctgt tatgcagttg ttttcttcat agagaatagc
     4621 tgaatcttca accctatcta gtaaaccatc taaggttgta aacttaaaat caacatgaag
     4681 aacaggggaa tcatagaggg aaattatcaa tcgaggttct ccaacgtgtt cgccagtaaa
     4741 agcagaaact aatgttccaa actgttccac aataagtaat ctctcttcga taacttcttc
     4801 ataggattta tcatctgcta caatcagaaa atccaaatca gaatattcat ctaacgattt
     4861 tgtgatataa gaactgctaa ttgcaagtcc tattatccta ctatctcttt ttgaaaattc
     4921 taatacgttt tgtatcattt tctgttgtgt tttagtcata atataacacc tctcactgtc
     4981 ttttattagc tatcaatcca acataattat gcataggagt attatataat gaagaaataa
     5041 aaaaaaatag gtcacttgac ccgaaataaa aaagcattga ataattatta ttcaatactt
     5101 ttttgaaatt atacttatgt tgtaggaaga ttctttaata cctctcgctg attaattaca
     5161 ctaaatcttt tgttttcata agcaattaga tgttcttgta cacattcatt tatagcacga
     5221 ttaatgcttc taattggagc gtttacttcg ctagcaagct gttttttggt aagcagattt
     5281 aattcacttc tataatagtg taaggatata cacctcagaa gtcgttcttt aacacttaaa
     5341 gatgataatt cttcaattaa ttcagcattt acaactaatt tactagatat ttctcgaatc
     5401 agaaattttg tagcttcaaa atctcccctt aaccagttta aaaaatcatc tctatgaagt
     5461 ttatatacat tacaatctgt gaaagcgaca atttcaacgg gttttttccc atcattaaat
     5521 tgttccattt ctccaaaaaa actaccactt ctataaagat gaatcgttga gatgtttcct
     5581 ttcacattta agatgaatgc ttctgcaata ccgtcaatca taagaattac atattcattt
     5641 tcttgctcag caaaaagaat agtctctttc tttttatacg tttttttaac aagcttcttt
     5701 ttaatatctt cattcataaa atcaattaaa tgcatattca tccctcctta ccaaatcttt
     5761 gattaaatta tatcatcttt caattagtta ggtaagatag taaaaatata tttacataga
     5821 aactattcca ttattatttt ccagttgtca tttttctgca aaaacttatc actgtcacga
     5881 ctggagatac cagtaaggaa tgttaggata tcaatcgcta aactttcaga atccttttta
     5941 cggctcaaaa tgacgtaagg gtcaagcaat cctttgtttt catcattact ggttaaattg
     6001 acaatgttta tctcatgggc tatttctggt agcgtttctt tccatttgcc gcgttctgct
     6061 ttagggtcaa ctatgaccgc ctgtccgccg aatagtaccg catagtaaac aagcatattg
     6121 ttactgaata atttaccacc acccaatgaa ccgataaacg cagacgctaa cgcattggta
     6181 atagaaccct ttaccccttg actagcaagg gcaggtttta gatagacatt ctttccagtg
     6241 tccagattgt agccaagata gatatcctca tgttcgccaa gggtttgtgt cgctccaaaa
     6301 ccaagtccag ccaaaaaatc cgaagtgaca tattgaatat aatcattgat gtaacgtttg
     6361 ctgacaggaa taaattcgcc atgcaatccc aacatatccc caaagggacg cacgagcttg
     6421 attgataagt cgtcgtaaaa gtctttgact tcatcacaac gcctttttag ctcgtcaaga
     6481 ttctttgtag atacacggac aacatagcta agtttataca tagattcttt acagttaaaa
     6541 gtctgttttt aaaaaaatgt ataaattata aatcaaaata tagatactat caatgaccca
     6601 ctaggtgcaa aaagcattga tatggttaaa ttatcagacg ctaaaagctg ggctatccga
     6661 atgagtgaag atgggtgtgc ttataaatcc attgacaatt ataagcgctc actgaaagcg
     6721 tcgtttttca tggcaattca agacgactgt attagaaaga atccatttaa tttttagtta
     6781 agtgatgttt tggaagatac aacagaacca aaaatcgctc taacaccaga acaggaaatg
     6841 ggcttattat cctttatggg gagcgataag acttattgta aatattatga tgatgttgtt
     6901 atcctcttag aaacaggact acgcatttct gaattatgcg gtttgacttt agaattggat
     6961 atgaaaaata aagccattat ggtagaccat caattgttga gtgatactaa gattggctat
     7021 tatgtagaag ttccaaagac cacacagggt aagcgagaaa ttccaatgac tgaaagagct
     7081 tatcaatcat ttgaacgtat cgtggaacgg cgtaagaacg ctaaagcaga accaatcatt
     7141 gttgatggtt accagaactt cctatttctt aaacaagatg gattaccaaa acaagcaact
     7201 cattatcaaa gcatgttaag agcgttagtc aagaagtata ataagaccca tgaggacaag
     7261 ctaccaaaga ttacgccaca tacctttagg catacactct gtacaaatat ggctaacaaa
     7321 ggaatgagtc ctaatatatt gcaatatatt atggggcata aaaacattac tatgacgctt
     7381 ggctattatg cacatggttc atttagttct tcgagagctg aaatggaacg gttataatcc
     7441 tagtagtatg actagagttt actacttatt tactactttt gatggcattc ttatacggtt
     7501 aaatgccaac ttatgcaaag tatcttccaa aaagaaaatg ccgatactcc ttgtagatac
     7561 aggatatatc gacatttacc aacttatgaa aagataatca aatttaatat aagtttttca
     7621 aataaaaaga taccaaattc tttttcgaga atctatataa cattacttaa gcttggttgg
     7681 ggtataaaca attgagtagc tacttttgta tggtgttcaa ctttagtcaa aactcttaag
     7741 taatgcaaat gatttagatt cattaatatt caatctcttc ataagtagtg aaattcgagt
     7801 tatttctgca taattatact atgatttata gattaattct attagcatcc agaataatat
     7861 tgtttatatg agtaaaattt aaagaatatt gtgaaaatta taggatgtta aaataaattt
     7921 aggtaaaaaa gaagtgtttg tatattatag agtacctttt ctaaaatatg tgggattgtt
     7981 ttaagaatta gaataaaaat tatttttaaa ttagtatttt tataatgtat agtattttta
     8041 atgtataatt aaattgtgca gaaaatagaa tttaaagtcc tatagaattt ctgattatgg
     8101 aggagaatat gaaaagaaaa gttcaagtaa aaaatattac tattggagaa ggtagaccta
     8161 aaatttgtgt accaattatt gggaaaaata aaaaagatat tataaaagag gctaaagagt
     8221 taaaagatgc atgtttggat attatagagt ggcgagttga tttttttgag aatgtagaaa
     8281 atattaaaga agttaaggaa gttctctatg aattaagaag ttatatacat gatatccctt
     8341 tattattcac atttagaagt gtagtagaag ggggagaaaa attaatatca agagattatt
     8401 atactacttt gaataaagaa atttctaata caggtttagt agatttaata gatgtagagt
     8461 tatttatggg agatgaggtc atagatgaag tagttaattt tgctcataaa aaagaagtga
     8521 aagtaattat atctaatcat gattttaata aaactccaaa aaaagaagag attgtatctc
     8581 gtttatgtag aatgcaggaa ttgggcgcag atttacccaa aatagctgtt atgccgcaaa
     8641 atgaaaaaga tgtgttagtg ctacttgaag ctacaaatga aatgtttaaa atttatgcag
     8701 atagaccaat aataacaatg tcaatgtcag gaatgggtgt tataagtaga ttgtgtggtg
     8761 aaatatttgg ttctgcattg acttttggag ctgcaaaaag tgtttcagca ccagggcaaa
     8821 tatcatttaa agagttaaat tcagtactta atctattaca taagagtatt aattaaatta
     8881 attatataga aatattagac ggtatttttg aagatataaa ttaaatataa aaaacttttc
     8941 agatagtaaa atttaaattg ggcaattata tctgaaaagc aactatttag tgtgtatttt
     9001 gaaagtgata tagaaaatct tataaatcaa ctatggcata tttaaaatat gccattaaaa
     9061 cctactagac attagattat agatggtata ctagcatttc tattatttat agatagtaag
     9121 ttttcataat aactgtttta tctaaagtag aagatatatt tgtattatgt atatttgtca
     9181 ttattttttt gtaattatgt atattaatgg ttatatatgt aatataatat tatcactcta
     9241 ttttttgtat attgtacatt acaacattta tatctatcat catcaattac agtagaatgt
     9301 atgggatact tattttcact taaccaatat ttttgcatat tctttgtcca agactttgga
     9361 aacttcaata ctttcttgtt tattataaca tcctcatctt caaaaatatt aacttctctt
     9421 tctattttta tttttctgtt gtatatctta ttgatagatt ctttgtcgag ttttatgtct
     9481 ctatacatat cagggcaata gcaacaaaca taatttcttt tttttcgacg tttaaatttc
     9541 acaactttct ctatgctaat ttctaatttt tttgtaccat cttttataaa tttaatatct
     9601 tctatgttct cgcttgaaaa aatttctgtc aatcttaaag tatctacagt ttctctaatt
     9661 atttgctttt tataagaaga gaatccatat ccaaaagaaa ggtttaattt attagggatg
     9721 tagccatttt tatatttaaa catcttaatt ttttccaatt cagcattatc tttaaatttc
     9781 aacttttcat acctaaaagt tactttgcta aaaagagtat attctacatc aatatattct
     9841 tttgcaatct taaatttatc gctaccttca atcacaatca tagcctatct ccaatcgttt
     9901 tatattaaaa taaggccata gaacatggtc taatagtact cattagcact ataagacaat
     9961 gttaacacaa aaagacaaaa aaaggttatt tatttcaaat aacctttttt tttatataaa
    10021 atataaagaa ttatatttta ttctttttta tgatgtctat aatctgtgat atcagattta
    10081 gttctcttga atttaagtct tttaactctt catttatatc attttctaaa tatgtttttc
    10141 cagtggaagt aatatctttt ataagaacat ctgcagaaat atttaatata tttacaaatt
    10201 ttatgaatgt tttaagactt ggattctttt taccactttc gatttgagtt atataccaag
    10261 gcgatactcc aaccatattt gcaaattctt ttgaagttaa atttgctttt ttccgttctt
    10321 ctttaagtct tttacctata taattcatta ttgttactat ttccctcact tatatttctt
    10381 tgtatttaat gatgcacttt attaactcta gcattgcaat ttgttctttt tcagttaatt
    10441 tattaatcat ttcataacat tctaaaggta cagagttatc aacgccttct gttgtaataa
    10501 tatttgcaaa taacaattca agtggtatgt ctaaagcagt agcaattttc attataatat
    10561 tgatagatgt atttgtctca gctctttcaa tctgaccaat atatgttgga tgtaaacctg
    10621 ccttttctgc tagaaactct tgactatatc ccaattttgt tctatagact tttattctat
    10681 ctcctattat ttttcctata tttgccaatt attatccctc cactttagat tatattcata
    10741 gtttaagttg ttttatatag actatttata cttttttagt ctaaatatag actatatatg
    10801 tttttatact gaaataagtg ctatttattt ttgtatagtc tgtatctaca ataaacaaat
    10861 atggataaat catattttta attagagaaa tattttcata atttcatagc catactacaa
    10921 taataaaacg aattaataat atgttaatta tagcattttt tattgtaatt acatattaga
    10981 tatgtagaat atattttgaa aattaaaaaa attttctatt ttat
//
LOCUS       DAEHWO010000110        10995 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEHWO010000110 DAEHWO010000000
VERSION     DAEHWO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.113"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            139..1635
                     /locus_tag="KNP54_003566"
     CDS             139..1635
                     /locus_tag="KNP54_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBF0894423.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            1769..2695
                     /locus_tag="KNP54_003567"
     CDS             1769..2695
                     /locus_tag="KNP54_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0894424.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINGAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            2813..3004
                     /locus_tag="KNP54_003568"
     CDS             2813..3004
                     /locus_tag="KNP54_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894425.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            3227..3577
                     /locus_tag="KNP54_003569"
     CDS             3227..3577
                     /locus_tag="KNP54_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894426.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            3838..5343
                     /locus_tag="KNP54_003570"
     CDS             3838..5343
                     /locus_tag="KNP54_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBF0894427.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            5733..6830
                     /gene="dinB"
                     /locus_tag="KNP54_003571"
     CDS             5733..6830
                     /gene="dinB"
                     /locus_tag="KNP54_003571"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBF0894428.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            7093..8229
                     /locus_tag="KNP54_003572"
     CDS             7093..8229
                     /locus_tag="KNP54_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894429.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            8222..9769
                     /locus_tag="KNP54_003573"
     CDS             8222..9769
                     /locus_tag="KNP54_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBF0894430.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            10104..10970
                     /locus_tag="KNP54_003574"
     CDS             10104..10970
                     /locus_tag="KNP54_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBF0894431.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
BASE COUNT         4255 a         1154 c         1983 g         3603 t
ORIGIN      
        1 ttacatatat aatattttgt atataactta acaaagtata tgcctatgtt ataataattt
       61 atagaaataa ataaaaaata caatatacat aatagtagaa atatagcaaa aaggtgtgat
      121 ttatagggag gattacttat gtttgaattt gaaacgcaac taaaaaggtt aaaacatgaa
      181 gttttaacag cagtagcaag actatctatt gaagaaaatt taacaaaaga aaatatagaa
      241 aaaattccat atgaaataat taaaggagaa aaggcgagat atagatgttg tgtttataaa
      301 gagagagaag tagttcttga aagggcgcaa cttgcattaa gtttaactcc aaatagtaaa
      361 tatggagata taaatccaga ttcagttagt ttggacacag atgagcaaat tatatatata
      421 gttgaagcag catgtgatag atgtccaata aatgaattta cagttacaga gctttgtaga
      481 gggtgtttgg ctcatagatg taaggaagca tgtaaatttg gggcaatttc ttatataaat
      541 gggagagcat atataaatca tgatttatgt aaggcttgtg gaatgtgcaa aagttcatgt
      601 caatatgatg ctatatcaga agttgtaaga ccttgtaaaa gcgtttgtcc aacaggagct
      661 ttggatttta atagaaacac tatgaaagca atgatacatg aagataattg tataaattgt
      721 ggagcatgta tgtcagcatg tccttttgga gcaatatctg ataagagttt gatagcacct
      781 gttgcaaaaa aacttgcaaa gaaagaaaat atgtatgcaa tagtagctcc agctataaca
      841 ggtcaaatag atagtaatat tacatatggt cagttaaaaa atgctataaa atcactggga
      901 tttgtagata tgatagaagc ttcttgtgga gcagatgcag ttacagttca tgaaagcaat
      961 gaacttattg aaagaataaa atcaggagat aattacatga caaattcatg ttgtccggga
     1021 ttttttaagt atatagagaa gatgttccca gatgaaaaag atagaatatc atctacagtg
     1081 tctcctatgg tagcaacagg aagattagta aaaaaaatag attctgatgc taaagttgta
     1141 tttataggtc catgtacagc taaaaagagt gaggcaacag agaaaagttt aaaagattca
     1201 gtagattatg tacttacttt tgaagaacta atggcattat ttgaagcatt taatatagat
     1261 ttatcaaaat gttcaaatga agatataaat gatggttcga tttttggaag gggatttgga
     1321 gcatctggtg gacttgccaa atcagtacag aactatattg ctgaaaaggg gcttagtttt
     1381 gattttgaac ctataaaagt atctggtcca agacaaatta aaaagacaat gacaatggct
     1441 aaattgggaa gattagaagg taattttata gaaggaatga tgtgtgaaga aggttgtatt
     1501 aatggagccg gtaagttttt atcaggtgta aaagccaaaa atacttttga tagaaaaaat
     1561 ggacaatcta ctaaaaagag tgttttatct aatgataaga ttaaagaatt tgaagatgta
     1621 aatttagaaa gataattgtt ttggtacagt cattttttta ttatgccaca aatatgccta
     1681 aaatttgccc tttttatatg tgtattttac agagttaagg ttgctatact ataaatatgt
     1741 aataaataaa atttatagga gcttttggat gaggaaaata gtattaaaag atatcctgtt
     1801 tttagttact acattatcta taatagtaat attattgctt gtaacaaata taactactaa
     1861 tagtaagata aaatcaacaa gtgaatctta tttaaaaagt gacaaaaata gtgtgaggca
     1921 aaatggtatc cagaggagca caaagagtag cacaaaaaat actgcattta agactactat
     1981 actaaacact ggaaagtctg attgcatatt ggttgagata ggtaacaaag tcataatgat
     2041 tgatacagga gaagataaaa atggaaaaca aatagtggat aggttaaaag aaaaaggaat
     2101 aaatacactt gactatttga ttttaactca tttagataag gaccatatag gtggagtaga
     2161 tagtgtgtta tctagtgtta aagtaaagaa tattatacaa gcaaattata agaaagatag
     2221 taagcaatat gatgaatata ttgactcact taaaaaagct gatatagaac cagtgctact
     2281 aaaagataat atgaatattg taatcaatgg tgcagaaata aacatacatc cggcttcaaa
     2341 aagcaagtac gagagttcaa atgattattc aataatcact aatataagct atggagcaca
     2401 taagttttta tttgcaggag atgcagagga agaaagattg tcagagttta taaatggaaa
     2461 tactttaaaa tatgattttg ttaaaatgcc tcatcatgga agatatgaca aattaactga
     2521 aacattttta gagtctattt cacctcaata tgctgttatt acatgttcag agaaaaaaga
     2581 accagaggaa ggtgttttaa aaatattgga aagattgaat ataaaaacat ttttgacttc
     2641 taatggagag gtagttatca atagtgatgg taagacattg agtgtgaatc aataattttt
     2701 ttaaaaatat ctaaaaaaat ttaaaaaaat cattagcaaa tattacccct taaacatagt
     2761 atattttagg agctgaaact ccacatacaa aatgactagg aggtaacata ttatgttgga
     2821 tagatttttt ggtgaaggcg gatttggtgg atgtgcttgg tggataataa tattattctt
     2881 cttattctta gcattccaag attgttgggc tgaaatggac ttatgtgcat ggataccttt
     2941 cttaatatta ttattaatac tttgtgaatg tggtgacgtt tttgatggag gatgtggatg
     3001 ctaaaaaaat caatttagat gatttaataa agcttatggt gggtataaat aaaataccaa
     3061 accaatcaca atctagtgtt tgaaggtagt cggaaatccc ccgctacctt ctttttttta
     3121 ttgttaaaat ttatttttga attatttcat ttacatataa taatttttac gataaagtct
     3181 gatataatta aaaagaaaat aaaatttatt tataggagat gtaaaaatgg ctatagtgga
     3241 taagattttc aatgagataa aacttatggt tgcaagactt ttattgggaa aaaaatacag
     3301 tgaatatgaa gaaaaagatt tagtgtataa tacagaagaa gaagttatac ttataacttt
     3361 aaaaagatta gtttttcagg gaaatgtaaa cgaagcagaa gaaattttat ttgataaagc
     3421 taagagtgta aatagtgaaa atatgcagta tatagcaata gaattttata ctatgcttat
     3481 ggaaaagact gatgaagaat tagaagctat gaatttttct aaacaagaag tttatcaagg
     3541 tatagaagat attagaaaag tattgaattt agaataaaag atatatgaaa atattgaaat
     3601 aaattaatgc taaggtgaga atattatact tatatataaa aatatagtat tcttatttta
     3661 ttagttatat aggtatatct tatttaccat aaaactatct tgaaaaaaat taatcttaat
     3721 tgtataatat tactttgagt gaaaaagtat taacattttt ttataagatg ttttactaaa
     3781 aaaatatata taaatatact gttatcaaca agaaatttaa tttagtgagg tgttaagatg
     3841 aaagtaggat ttgaccacaa aaaatattta gaagagcagt ctaaatatat cttagaaaga
     3901 gtaaataatt ttgacaaact ttatttagag tttggaggaa aattgatggg agaccttcat
     3961 gcaaaaagag tacttccagg atttgatgaa aatgcaaaga taaaagtatt acaacatatg
     4021 aaagaaaaag ttgaagttgt aatttgtgtc tatgcaggag atatagaaag aaacaaaata
     4081 agaggagact ttggtatcac ttatgatatg gaagttttaa gattaataga tgatttaaga
     4141 ggttatgaac tagatgtaaa tagtgtagta attactagat ttgaaggaca acctgctaca
     4201 actgtattta taaataaatt agaacgtaga ggaattaaag tttataagca ttatccaaca
     4261 aagggatatc cgtcagatgt tgagactata gttagtgatg agggatatgg agcaaatgaa
     4321 tatatagaaa ctacaaagcc aatagtagta gtcacagcac caggacctaa tagtggaaaa
     4381 cttggtactt gtctaagtca gttgtatcat gaaaataaaa gaggtaatgt agttggatat
     4441 tctaagtttg agacattccc agtttggaat gtacctgtaa aacatccttt gaatatagct
     4501 tatgaagcag ctacagttga tttaaaagat gtgaatatga tagattcatt ccaccttgaa
     4561 acgtatggtg aaatgtcagt aaactacaat agagatttgg aattatttcc agtgcttaaa
     4621 aaaataatag aaaagataac tggaaaagaa tcaattttcc aatctccaac tgatatgggt
     4681 gttaatagag ttggctttgg aataatagat gatgaagtaa taagaaaagc ttctatagaa
     4741 gaaataataa gaagatactt taaaactgcc tgtgagtata aaaagggaca agttgataaa
     4801 ggtgcttatg atagaatgaa aatgattatg gaagagctta acttaaagcc agaagataga
     4861 aatgttgtat tacctgctag aaactacagt aataaattga aagaaagtgc cgacaagaat
     4921 gatacttgtc ctgtagttgc attagaatta gaagatggta caatattaac tggtaagggt
     4981 tctgatttaa tgaatggaac tgcagcagta gtattaaatg ccattaaaca tttagccaat
     5041 atatctgatg atatgcactt aatatcacct gtaatattag aacctatcat aaacttaaaa
     5101 acaaagactt tagctagtag aaatgtttca cttagttgcc aagaggtgtt aactgcactt
     5161 agtatttgtg ctgtaactaa tccaactgca caatttgcta tggaaaagtt agcattatta
     5221 aaagggtgtc aagctcattc tactactata ttaaatagag atgatgaaca aacatttaga
     5281 aaacttggta tagatgtaac ttgtgaccca gaatatcctt cacaaaatct ttactatagt
     5341 taaaattata taaaaaaata tgggctgttt taaagtaata gtttgagcag tccattacaa
     5401 ttataataaa atcagtaggc tgtcttgtat aagacagtct tttgttttta aaacatccca
     5461 taaattaaat atatatactg ttatccataa ggaattttaa atttagttcc ttggaatacc
     5521 tattgtaaag cttttatata gtttttgcaa gtgtttttaa ggatttttta taaattatat
     5581 tgaagttaat ggattataga tggttttatt tatggaaaat atgaatatat aaagaaaata
     5641 atgaaaaaat accaaaaaga aacataagtt tggtataatt aaaaagtaat ataaataaaa
     5701 ttaatctatt tatactttaa aaggtgataa taatgaaaca ttatagaaaa ataattcata
     5761 tagatatgga cgctttttat gcatctatag aacaaagaga taataaaaaa ttaaaaggaa
     5821 gacctgttat tgtcggtgga aatccacaaa gccgaggtgt ggttgcaacc tgttcttatg
     5881 aagctagaaa atttggtatc cattcagcta tgccatcagc tgtagcttac aataggtgtc
     5941 catatgcagt ttttgtaaga cctagatttg atgtttataa gagtgtgtca gagcaaataa
     6001 gagatatatt ttatagatac acagatttag ttgaaccatt atctttagat gaagcttact
     6061 tagatgtaac aaaaaataaa aaaaatattg attcatcaat tgagatagca aagcaaataa
     6121 aaaaagatat atttagagaa gttggtctta cttcttcagc tggtgtgtca tacaataagt
     6181 ttcttgctaa gattgcatca gacttaagaa agccaaatgg gttaactgta ataaccgaag
     6241 aaaatgccca ggacttttta gataaattac ctgtgaataa attttttggt gttggaaaag
     6301 ttacttcaaa tactcttaaa aatttaggta taaaaactgg atatgattta aggtgtttaa
     6361 atttatttga acttgaaaat atattcaaaa aaagaggtta tgaattatat aaatttgcta
     6421 gaggaataga cgatagacca gtggaaccaa atagggttag aaaatctgtt ggggctgaga
     6481 ctacattaag tcataatttg gatattgatg aagaagaaac acgcaacatt cttgatgaac
     6541 tttgtgaaga agtatgtcat agattaaaaa actctgagaa gtttggaaaa acattaacat
     6601 taaaaattaa atatgaggac tttacaaaga taactagaag ccttagttta gaacactata
     6661 ttgacgaata taatgatata agaagtggtg tagataattt gttgagaaat gttgaggtta
     6721 atggaaaaca aattaggcta ttgggagtta caatatcaaa cctaagtgat aaaaaagaaa
     6781 cttataaaga tattacatta tttgaataca tggatagtat ccaaatgtga gttttgttta
     6841 aatgaaataa cactagcttt aatactatat aattgaggct agtgttattt tatgaatatt
     6901 tttatatttt ttgttttttg acattgtata ttatatacta tatataaata ctttatattt
     6961 gtagcaatat tcagacaaat agtgacctaa aaatcgtact ttgtttacat aaataaaata
     7021 gtatgatata attataaaaa caacttataa tattggagaa ggttgcttgt tcgaaaaagg
     7081 ggatgataaa ttatgataga gataagaaat gtaacaaaaa aaataggaaa taatgttata
     7141 ttagatgata tttctctagt tgtagaaaca ggtacattgg tagttttgat tggttcaagt
     7201 ggttgtggaa agactactac tttgaagctt ataaacaaat taataaaacc tacatctggt
     7261 gagatatata ttaatggcaa accaatttct caggaaaatg aaatagagct tagaagaaaa
     7321 ataggatatg ttatacagaa cacaggccta ttccctcatc ttacaataaa agaaaatata
     7381 gagctaattc cacgcctaaa aaaggaaaaa tccgttgaag aaattgaaaa aagaacgttg
     7441 caactacttg agatggtagg acttgatagt gatgaatttt tgaataagta tccttcagaa
     7501 cttagtggtg gacagcaaca aagaatcggt gttgcaagag ccattgctac tgatgctgaa
     7561 ataatattga tggatgagcc ttttagtgct ttagacccaa taacgagaac atctttacaa
     7621 gaacaattat tttctcttca agatgaattg aaaaaaacta taatatttgt aacgcatgat
     7681 atggatgagg ctttaaagat agctgataaa atttgtatta tgaaggatgg aagaatagca
     7741 caatatgata ctcccgaaaa tatacttaga aagcctgcaa atgactttgt aaaagatttt
     7801 atcggagaag atagagtttg ggataatcca gaatatataa aagcaagaga tattatgata
     7861 aaaaatccta ttgctgttaa ttctactaga actgtaactc aaggaataga aattatgaga
     7921 acgagtaagg ttgatagctt actaattata gatagagcaa aaacattaaa aggtattgtt
     7981 actgtaaaag atatgaaaga tattgatgat aagtcaatat tacttgctga tattatgtca
     8041 agtgagcctt tgcatgtaaa tgaaggggat aatttagtag aaatactaaa tgtaatgaat
     8101 cgtaattcgg ttggatatat tccggttatt tctgatgaaa ataaactggt agggcttatt
     8161 actagaagta gtttactttc tgttttaagt gaacaattct tagaaatgga ggtgagtgtt
     8221 cttggctaat ttttttaact ttatactatt acaaaaagat aagattatag agcttttaat
     8281 acaacatatg agtctaactg ttacatctat tttaatagct ataatagttg gtgttcctct
     8341 tggaataatt atttcaagaa tctcatctct tagaaagttt gtacttggat ttgtaaactt
     8401 agtccaagca gttccgtcta tggcactttt gggtcttctt gtacctatac ttggtatagg
     8461 aagtaaacca gccatattta tggtagtggt ttattcatta ctaccaattg taaaaaatac
     8521 gtatataggt ataacaagta ttgacccagt agtattagaa tcagctaaag gtattggtct
     8581 tacaagaaat cagacattat ttaaaataca attcccttta gcacttccta taataatggg
     8641 tggagttaga atatctgcag ttacagctgt tggtttgatg actcttgcag catttatagg
     8701 tgctggtggt ttaggatatt tagtattttc aggggttcaa actgtaaata ataatatgat
     8761 tttagcaggg gcaatcccat catgtataat tgcactgtta gttgattatt tatttagtaa
     8821 aattgaagtt gcagttactc caaaaggatt aaatccaaaa gcacctaaga agaattatat
     8881 agcacttaaa gtaatatctg tagtggttgt tgtttcaatg ttgttcgttg tttttagttc
     8941 tagtttttca agtaaaaaag atacaataac tattggttct aaagattata cagaacaact
     9001 tatacttggt aatgtttatg ctgaattagt agaaaaaaat acgaatctta aagttaagaa
     9061 gaatttaaat ctaggtggtt catctgttgc gtttaatgca attaaatctg gtgagttaga
     9121 catgtatgtt gactatacag gtacactttt ggtaaatgta atgaaacatg ctccgattaa
     9181 agatgctgat gaagcatata atgttgtaaa agatactatg gaaaaagaaa atcagttaac
     9241 tttacttgac cctcttggat ttaataatac ttacacatta gctatgatgc ctgaaactgc
     9301 tgaaaagtat ggaataaata ctatttctga tttgactaaa tatggtaaag aatttacatt
     9361 ctcaccaact ttggagtttg aaaatagaga agatggtctt gtagggcttt ctagagatta
     9421 tggtttaaaa ttcaaagatg taaaagcaat gaatggaagt ttaagatata cagctttaga
     9481 taataatgaa tctcaggtta tagatgcatt tttaactgat ggtcttatta aaaagtttaa
     9541 tcttaagata ttagaggacg ataaaaattt ctttgtacca tattatgcag caccattagt
     9601 aagagaagat actttgaaga aatatcctga gttagaaaaa gttatgaata tgctttcagg
     9661 aaaaataaat gaagaaacta tgagagaact taactatcaa gtggatgaac ttggtaaatc
     9721 accagaagaa gttgctcatt cattcttagt taaagaaggc ttagtataaa aaattaatag
     9781 tttatatcaa aaaatttaag agagtgtctc aaaatgaact ttttagttca tgaggcactc
     9841 ttttttatat gaaatcaaat atattttatc atttcaacaa taaaaaagaa gattatcttt
     9901 attttgagac agtctcttat ttttatgtat accaaaacca tacctacgat ttttatttat
     9961 aattaagttt caaatagaat gaacaagtac aaccaatttt gaatataaat atagtaaatg
    10021 tgcttatata cgattttatt gtctggttga ttgatattga tagatagctt tctttattga
    10081 atcgaaggga gggggaattt gttatggata actataagaa agtgaagcaa gtattgtgga
    10141 taattttatt tgctaatttt gcagtagcat tattaaaaat cattattggt aatcaaataa
    10201 aaagctatag tatgacagca gacggatttc attctttgtc agatggagca tctaatatag
    10261 tggggcttat aggtattttc tttgcatcta aaccaaaaga taaaaatcat ccttatggac
    10321 ataaaaagtt tgaaattata accagtttat ttataagtgg tatgttgttt gttatagcaa
    10381 ttaagataat tcttagtgca gtgttaagaa tagctaatcc agttgtacct gctataacta
    10441 tagaaagttt aattgcttta attattacac tttttataaa tatttttgta tgcatgtatg
    10501 aatatagaat tgggactaaa ctaaatagtt atgttttgat ttcggattca ttgcatacaa
    10561 gaagtgatat atttgtgtct ctaggtgtat tggttacttt agttggtgtt aagttaggat
    10621 ttccagtaat aatagaatct atagttccta ttattatttc tgcattcata atttattcgg
    10681 cttatggaat atttaggcca tctattggaa ttttggtcga tagagtggct gtagatgagg
    10741 attatataaa agaaattgtg tttgaattta atgaggtaag ggatgttcac aatatcagaa
    10801 gtagaggtag caaaagttct atttatattg acatgcatgt aatggtagac ccatttataa
    10861 gcgtagagca atctcatgat ttaacacata aaattgagaa acaaatacaa gaagaaatta
    10921 atgaaaatgc tcaagtaata gtccatattg aaccttttta tagtttttaa cttagctata
    10981 aaatacaagt tataa
//
LOCUS       DAEHWO010000111        10840 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEHWO010000111 DAEHWO010000000
VERSION     DAEHWO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10840
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.114"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            430..1209
                     /locus_tag="KNP54_003575"
     CDS             430..1209
                     /locus_tag="KNP54_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBF0894432.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(1519..2340)
                     /locus_tag="KNP54_003576"
     CDS             complement(1519..2340)
                     /locus_tag="KNP54_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HBF0894433.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADILIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIVTHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(3350..4168)
                     /locus_tag="KNP54_003577"
     CDS             complement(3350..4168)
                     /locus_tag="KNP54_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBF0894434.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4336..4917
                     /locus_tag="KNP54_003578"
     CDS             4336..4917
                     /locus_tag="KNP54_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0894435.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            4914..5102
                     /locus_tag="KNP54_003579"
     CDS             4914..5102
                     /locus_tag="KNP54_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894436.1"
                     /translation="MKIITIGSSLITVLLFLSTMICGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYI"
     gene            complement(5272..7014)
                     /locus_tag="KNP54_003580"
     CDS             complement(5272..7014)
                     /locus_tag="KNP54_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloendopeptidase"
                     /protein_id="HBF0894437.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            7443..8819
                     /locus_tag="KNP54_003581"
     CDS             7443..8819
                     /locus_tag="KNP54_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBF0894438.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            9130..9801
                     /locus_tag="KNP54_003582"
     CDS             9130..9801
                     /locus_tag="KNP54_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBF0894439.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            9990..10787
                     /locus_tag="KNP54_003583"
     CDS             9990..10787
                     /locus_tag="KNP54_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBF0894440.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         4028 a         1321 c         1605 g         3886 t
ORIGIN      
        1 taatactact ttttataata taatcaatac tgattctaca atataattaa cactactttt
       61 ttaaatataa tcaatattga ttctacaata ttattaatac tactttttac aatataatca
      121 atactgattc tacaatataa ttaacactac tttttaaata taatcaatat cgattctata
      181 atattaacac tactttttat aatataataa atactgattc tataatataa ttaacactac
      241 tttttaaata taatcaatac cgattctata atattaacac tattttttat gctatataac
      301 aattattgaa aatgatataa atataatatc tcaaataata tgaatataac atctgaatag
      361 agggtgtttt atttgtaaaa aataagttta cagtttgagc gtataaactt atggtaaagg
      421 agaataatta tgagttataa gaagattgca attataacgg gtgctaatag tggttttggt
      481 aaagagtttc taaagttatt aataaatgaa gaagaaataa cagaaatatg ggcagttgca
      541 agaaacaagg cgagattaaa tcaattagta gatgaatttg gaagtaaggt aaaaattttt
      601 tcaaaagatt tatcaaaaat agaagaagta aaagaaattg gtacattttt aagtaaagaa
      661 aatgtatgta taaaatacct tataaacaat gctggttttg caaaattctg ttcatacaat
      721 gatttaagta tagatgaatc tattaatatg attgatttaa atattagtgc tgttgtagca
      781 ttgggactta tatgtattcc atatatgcaa aagggaagcc atatcatgaa tatttcttca
      841 caagcatcat tccagccatt gccatatcaa aatatttata gttcaactaa agcgtttata
      901 agaaattata caagagcatt aaatgttgaa cttaagagta aagggataaa tgcaattgct
      961 gtatgtccag gttggatgag tacaaatcta tttaagagag gtatagttgt agctgaaaaa
     1021 gggacaaaaa atttcccagg catagtgtct ccagacgttg ttgccaaaaa agcattgaag
     1081 gatgcaaaga aaaataagga tatttctgtg tatggtataa atacaaaatc cagtcattta
     1141 ttagcaaaac tattgccaca aaaaatgatg atgaaggttt ggttaatgca acaacatatt
     1201 aaggaataag agttttggta attaagtatc agttggagat tcaatctgtt atatattatg
     1261 agaagttttg ttgagcaaat aataattgtg acaaaacggc ttatctagtg acgataagcc
     1321 gtctataatg tatataaaat atatttttga ttttacttta tttagatatt gaagtattaa
     1381 aatatgtagg acttgaaatt ttataaagat aaatactatg atattttgta aaaactgcga
     1441 tatgttgata tcacatagtt tgactatact gttaaattga agttttctta ttttgcatta
     1501 tgcttattac ttaatgattt agactataat ttccatacca tcatatgcaa aataaatgtt
     1561 atcaagtttc ttttctaatt cactgtaata accatatgat tttccccaca tttcgtcaat
     1621 atgtgtaaca ataatttttt taattctata atagttttta atttcaacaa tctcatctaa
     1681 agtaaatatt tcatctttaa atggtgtgtc tttaagtttt gtaccatcat ttaatatacc
     1741 atcatcagaa actagactta ttattaaaat atcagcatca aagtacatat cactatgagt
     1801 aaatggcttg ggattacagc aggcatatat gacttttttt tcattctctt tgataacata
     1861 gaaggttata ttcctgtctg ggttattgtt aatcaaatca atatcaaaat tatttatctt
     1921 tacatgcgaa gtttcattaa tagaaatgca atttataaca tcaccataat atttaagaca
     1981 atcgagattc gttcggttta tatcttcaat tacttcagga agcgcataaa agccaattgg
     2041 attattttct cctgtgataa agtcacatcc tattttttcg acaattctaa tacccttaac
     2101 atggtctggg tcatggtgag aaattgaaat atgttttact tccgatattt tttgtctgtt
     2161 acaagctact gcaatgtctt caggtgtgtc tatcagcatt tttatatcat caatatataa
     2221 acttggtcct aatcgttcat atcttccgcc tttttgcctg gcttcttcac atattttgca
     2281 tttacaaaat gaacttggaa taattgacat accgccacta ccaacaattt ttaatttcaa
     2341 agttattaca ccaccttcta aaaatattag attatataaa taatatacaa gcacaactga
     2401 ttaacaaaat tatgagttaa taaattatat cacatgtaaa tatgaaagaa tagtatgaaa
     2461 tttttataaa catatattaa atgtttctca atgaaattga ctttgtatat gaactgaatg
     2521 acttattcaa tatggataag acatttttct tgtaataaga tatgattgtc ctataaggtt
     2581 tatgtaattt tgatataatt tgatataata tattgattaa caacatacat gttattggtg
     2641 agcatatttc tatagaatgg aatatataat tttttatatt tatcattgta ttattgtaca
     2701 aagaaagtta aaaagagtag agtacaaagg aattatttgt actttactct tttattgttt
     2761 tgttaaaaaa actaatttat attagtgatt aaaatatatt taactagagt ataaggatag
     2821 tatataatct tataattgat ttatctgaca aattaagata atatcctaat caaattctag
     2881 tcatttaaac ataaaatcat aattgattta tctgacaaat tgagataata tcctaattaa
     2941 attgtaggta tttaaacata acattataaa taatttatct gacaaattaa gataatatcc
     3001 taatcaaatt ctagtcattt aaacacaaca tcacaattga tttatctgac aaattaagat
     3061 aatatcccaa tcaaattcta gtcatttaaa cataacatca caagtgattt atctgacaaa
     3121 ttaagataat atcctgatta aattctagtc attcaaacat aacatcacaa gtgatttatc
     3181 tgacaaatta agataatatc ctaattaaat tgtagatatt tatacataac actaaaagta
     3241 atttgtttaa caaattaaga taatatccta attaaattgt aggtatttat acataacact
     3301 aaaagtaatt tgtctaacaa attaaaatat tatccaatta atataaaaat tacttctttt
     3361 taactgggaa gcatacctct gttacccaat tatcaggatt actatcgttg ccaggactta
     3421 catgataaat attaaacata ggaccatcca catcatagtt attatctgat atccaattac
     3481 caatagcctc acaagcgtct gcaacttgat tgaaatttcc attaacaatt gcagttgcag
     3541 cagtcacact tggaacagtc ttaaatttaa catgttcagt atctttatac tttccagata
     3601 cagcaacttg tacttcaaca tctacataat cttctttata tccagtatca taaaaaactg
     3661 ctttagaata ctttgggggt tcaatttgaa cattctggtc ttttgtctct aaaaatgctt
     3721 gatgccataa cattccttcg tcttgataag ttggtataac ccttctaagt gtcatcatat
     3781 attttggtgc aaaattcttt atagttacat cataattttt cataatatca tttcctccaa
     3841 ttcttttaat agtggtttct atttttaata gttttttctg tgtatcttct aattgttctt
     3901 ttacttgaga atggtggata tttagatatt ttatgagact ttctttatcg ttatattctg
     3961 tcaaaatttc ttttatagaa tacaagccaa agcccatatc ttttagtgca tggattctgt
     4021 ttgtagtaga aagttggtct gcactatagt atctatatcc attagtttta ttcgtatgag
     4081 aaggagttaa aagtcctatt tcatcataat gacgtaacat acgaatacta attttactta
     4141 gctttgaaaa atcgcctatc ttaaacatgt ttttgtctcc tttataaagg tacttttagc
     4201 ttaatattaa tataaaccat atcataatgt tagagtcaac taaaattata attaaattat
     4261 attgacatat gatgaaaaaa atattatact gaacatgttc agaactgaaa atgttaattg
     4321 ttttggaggt ctattatgaa aagtaatgat aaagatgcta gagaacgtat aattgaagtt
     4381 acattgaatc ttttaaatga agtagatgat attgaggaga ttacagttag aaaaattgct
     4441 gagcgtgcaa atgttggagt tggtttaata aattatcatt ttaaaacaaa ggataatttg
     4501 ttgagtactg ccataggaga tgtgatgtca aatataatag cagagctata tgacgatagt
     4561 gtatatactc taagacctat tgaagattta aaaaatttat taaaaaaatt gtgtgatact
     4621 ggattacatt atgaaaaagt gcttcctttt gtattgaatc aatgtataac caatggagat
     4681 atgcaagcag aacttgatat tgtccctatg cttcgtaaaa tttttggaaa taaaaaagat
     4741 gaaatgagtc taagaattat tgccctgcaa attattttac caatacagat ttctgcttta
     4801 tctacagaat catttcagtt atacagtggt ataaatataa agaataaata tgagcgagat
     4861 aaattcattg atattttaat agaaaatatt attggagagg atgttgatgt aagatgaaaa
     4921 ttataactat tggttcaagt cttatcactg ttttactttt tctttcaact atgatttgtg
     4981 ggttctggat taagaataat aaggtaacag atgcaagttc tattaagttc catatgaata
     5041 gtgctatttt tacagggata tttttattga tttccacaat ccttttaatt atatatatat
     5101 aaaaataata atattattaa taaataaagt atcagaaatt ataaagacaa gagtcttaaa
     5161 aatttctgat actttaccat ataattttat taaacattaa ttgtgtgtga aaaaatatca
     5221 cttatttcaa tctaatacta aatcttaaga gtgagtataa agtattagaa attaagaagc
     5281 attttttagt tcaagcggat tatctatacc aaaataatca tataaagtag agcttatttc
     5341 ctctaaattt ccatcttgga aaggtaattg taaatttacc ttttctacca catctttaaa
     5401 tccagcatca gtattttgat ttaaaaaatc catatataca tcaacagctt ttctgtaatc
     5461 ttcttgtgat aattgccata tctgaagtga tacatcagat gcaagaccat aactcaagta
     5521 ataaaaagga acttggaagt tatgagatac aagtatccaa aaaggagcat ttttttctct
     5581 aagtatatta ttggaaactc catattcttc ctctaaatca aaaaacaatt tattgatatc
     5641 atttagactc atatatggat tcttgtatat aatttcttga aattcatcat aaagacaagc
     5701 atcaataata gtatttaaaa caatcgataa gtgttctttt tttatagctt cagattgttt
     5761 accaaaaaaa tcatcaaaat atttataaaa tagaatttct aaagatgttg aatgaacttc
     5821 acatacatct atacttggtt gcatcttatt gtttaagtta atactgttgt agtaattata
     5881 aaaatgacca aactcatgag caaaactagt aacacctaaa aaagaattat cccatgtatt
     5941 aaacaagaaa ggtgctttat atttatttat ataagtagta tatcctccag gtgatttgtt
     6001 ttttccagaa gaataatcgt acaagtcata ttttttcata tagtcgaagc tctcttttag
     6061 ttttggagat atatcttcaa gtactttatc aaacttccta aatgagcgat ttttatatac
     6121 tttaatataa atagaagaat cagatggttt agatgaaatc tctctatata atggaactat
     6181 gtaatctttt acatcttgtc taaatttttt agcttcttct tgagaatagt ctttgtttag
     6241 gttcatatag gcataatcta tataattctt aaatccttgc ttacttgcta tttcagttct
     6301 tgtctgtata agttctaaga atatgttacc aaatatagga ttgtattttt ttaagtaatc
     6361 tgaataaatt ttcacatatt cttcagggct aagatttggt cttgacaagg cttcttcaaa
     6421 gtctacctct ataccatcta ttgatactgt agatttagct aataagtctt catattttac
     6481 aactaggtct tgctcttttt taagcaaacc ttcaacttct ttagaattaa gttttccaat
     6541 gttctttaga taattaaatg tatcctttcc aagttctttt tctaattctt tagagaattt
     6601 agaagttaca aatctatctt gaaagtcttt gtatgacatg tcaacatcta ctgatttact
     6661 cataagatac ttatattcct tagagtaaaa ttcgtctgat gaatctatgt tatttctaat
     6721 ttttgctata gtaagtgtac tgtaaaaatc ttgataaatt ttatcaactt cattaaataa
     6781 atttaattgt tccttagctg ttttagctgt taaaagtttg tcgttgcact tgttaatgtt
     6841 ttcgcaaatt gactgtatat taggacgctt atattccatt ttttcaaaag gaatagttcc
     6901 tctaacagaa tctttttttg tatcattagt ataatttctt atgtatgatg caaatataat
     6961 aaaaactgca attaaaatta gaaaaacaaa tattttcttc ttggatttaa ccataaaaat
     7021 cctccaatca tggatatagt tattaattat tttactatat taaatataaa aaatgcatgt
     7081 taagaaaatt taacataaag atatagataa gattataaat aatataaaaa atttaacttc
     7141 aaaaaagtat atgaaattta tactggtaaa atgataaata aattttaagt acaaaatagt
     7201 aaaagctatg atagttttag acctattata tgtaaaaaat atagatgttt ttggtgcaat
     7261 ttaaattaaa agatatatat aaaaatttaa aatattccaa acagaaatta taaaaattac
     7321 tatcattgtc tttatacaat atttatacta taatagaata ataatttaga ggaaagctct
     7381 aaaaataaac aaattaaggg tcttaacagt agtgatttta tgttaaggag gtataaagaa
     7441 agttgaaaac aatagttaga agacttattc tctacgcaga tggaatgcgt cctactcaaa
     7501 taatggtatc tgggtttgct gcgattattg taatcggagc attgttgtta acactcccga
     7561 tagcgtcgca gagtggagag agtataggct tattaaatgc tctatttacg gctacttcag
     7621 cggtttgtgt tactggtcta gttatggtag atacagcaac ttattggagt ttatttggac
     7681 agatagttat aataacattg atacaaattg gtggtcttgg atttatgacc gtagccacaa
     7741 tgttttcact tatggcacga aaaaaaatac aactaagaga aagattatta atacaagagt
     7801 cattaaatca agctgattta tcgggacttg taagacttac aagatttgta ttaataataa
     7861 ccataacaat agagggaata ggtgcactgg ttttatcaac tgtctttatt ccacaatttg
     7921 gtttgtctaa agggatatgg tatagtgtat ttcacgcaat atcagcgttt tgtaatgccg
     7981 gatttgactt gatgggcagt gtaagtggcc catttacatc gttaaattct tatgtaaaca
     8041 actttacagt atcaatgact gtttgcgcac ttatagtgct tggagggcta ggattccctg
     8101 ttgtacttga tattgtaaga aaaagaagat tttcaaaatt aaatgtgcat tctaaggttg
     8161 tattgttttc aactgctaca cttatttttg tgggtgcatt atttattttt cttatagaat
     8221 ttaatcaaaa agctactatg gcggacttgc ctttaaaggg aaaagtacta tcagcaatat
     8281 ttcaatcagt aacagcaaga actgctggtt ttaatacgct tgatttagct actttacgag
     8341 aaagtagtgt atttgtaatg ataattttga tgtttattgg agcatcacct gcatcaactg
     8401 gtgggggtat aaaaacaaca acactagctg ttttaatcat tacagttaga agttttctat
     8461 caggaaaatc agatatagaa gcttttgaaa gaagattagc tccatcaact ataaaaaaat
     8521 ctcttggtat atttgtaatc agtatatcag cagttatttt tggaacattg attatttcaa
     8581 taactcagcc taattttaca ttagttcaat cagcttttga ggttacatca gcacttgcta
     8641 cagttggttc aagtttagct ggaactccaa acttaaatgc tttaggtaag attataataa
     8701 taatctttat gtttatgggt agagttggtt ctcttacttt atttatggct atactttctg
     8761 gtggtagaag aaagagtcaa ccaatcagat atgcagaagg taaaattatg gttggttaag
     8821 ttaccaagga gtagtataaa tttataatgg gtttagagta gcactgtaaa tctgttgata
     8881 aaataaatga gcctagatgt aattatatga agaaataaaa tcaactaatg aacaaaatta
     8941 attaatgaaa taaaaaaaca gggaaataaa atacaaataa aaaggtaaat caaaattaaa
     9001 ttaatctgtg tgtataaaat tatatattgt gtataagttt tgtatgtgta aagtatataa
     9061 gttttgtatg tgtaaacaat taatttaaga gatattatat aaattgtgta ttagggagga
     9121 agtttcgaga tgaagcaata tatagtcatt gggtgtggga gatttggaag ttcagttgcg
     9181 tctactatgc atcttttagg acatcaagta atggcaatag acaaaaatga agattcagtt
     9241 caaagtatat ctgacaaggt aacccattca cttatagtgg atgttactga tgagcaagcg
     9301 ttaaggtcat taggtttagg taactttgat gtagcagtag ttgcaatagg ttctgatata
     9361 agggcatcta taatggcgac tcttatagcc aaagaaatgg gtgtagagtt gataatatgt
     9421 aaggcaaagg atgaattaca agctaaagtt ctttataaaa ttggtgcaga tagagttgta
     9481 tttccagaaa gagatatggg agtaagagtt gcacacaatt tagtttcgga taatatatta
     9541 gaccatattg aacttgaccc agagtattca attgttgaaa tcgtaactcc aaatagttgg
     9601 gttggcaaga cacttataga gcttgaatta agagctagat atgagataac tgtacttgct
     9661 ataaaaacag gtaaaaatat aaatgttaca ccttctccag atgaggaact tacagccgga
     9721 agtatcctag ttataatcgg tcaaaatact agtataacag cgataacatc tggaaataag
     9781 gggataatta gaagaagata atttactatt taatatatat ttaattgcaa tgaaagcaga
     9841 tagtatcata taattatgaa tagttatatg atactatttt tttaatcgaa ggtagtattt
     9901 atttgtaaga ttagataaag agaagttaaa ttaaaagtaa ggaggctgtg ctaatataaa
     9961 aatttataag ttattagcat ttagataaaa tgattacaaa tataaacagt aaggataatg
    10021 aaaagttaaa gtatacaaga gcactattaa aatcaaagaa taggaataaa gagtcaaagt
    10081 tcataataga aggatacaga atagtaatgc ttgcacttga atgtatggca aaccttgatt
    10141 atgtatttat caatgaagaa tttgaaaata agaaagaaca tgtaaaacta ttagaagatt
    10201 tggataaaaa aaacacaaag atatacaaga ctactaataa aaactttaaa gaattagtgg
    10261 atacagaaaa tactcaagga ataataggtg tagtttcatt taagaaaaaa aaattaagtg
    10321 aaagtataaa taaaaaagat aaatttgtat tgattttaga cagaatacaa gacccaggaa
    10381 atatggggac tataataagg actgctgatt ctgctggagt agatgccata atagcactaa
    10441 agggatgtgt cgatatatac aacccaaaag taattaggtc tactatgggt tctatttttg
    10501 atatgaatat aattgatgct tcacaagatg aaactgtgga catgcttaaa tcattggatt
    10561 ttaatatagt ttcaagttac ttaaatacag aaaattttta tgacaaaata gattatggct
    10621 caaaagtagc attggtgata ggaaacgaag caaatggaat aaatgaagaa cttgtatcaa
    10681 agtctgatat tttggttaag atacctatat atggtaaagc cgagtcgtta aatgctgcga
    10741 taagctctgc tatactgatg tatgaaataa aaaaatactt aatttaatgt attgtaataa
    10801 atataatgtc atgttataat cttgaattaa atagtagagt
//
LOCUS       DAEHWO010000112        10832 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEHWO010000112 DAEHWO010000000
VERSION     DAEHWO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.115"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            295..1455
                     /locus_tag="KNP54_003584"
     CDS             295..1455
                     /locus_tag="KNP54_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBF0894441.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1797..1958
                     /locus_tag="KNP54_003585"
     CDS             1797..1958
                     /locus_tag="KNP54_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894442.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2151..2780
                     /locus_tag="KNP54_003586"
     CDS             2151..2780
                     /locus_tag="KNP54_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBF0894443.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            3019..4278
                     /locus_tag="KNP54_003587"
     CDS             3019..4278
                     /locus_tag="KNP54_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBF0894444.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4537..5532
                     /locus_tag="KNP54_003588"
     CDS             4537..5532
                     /locus_tag="KNP54_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBF0894445.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5778..6845
                     /locus_tag="KNP54_003589"
     CDS             5778..6845
                     /locus_tag="KNP54_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBF0894446.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFAEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7379..9289
                     /locus_tag="KNP54_003590"
     CDS             7379..9289
                     /locus_tag="KNP54_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBF0894447.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNVGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9352..9975)
                     /gene="ytaF"
                     /locus_tag="KNP54_003591"
     CDS             complement(9352..9975)
                     /gene="ytaF"
                     /locus_tag="KNP54_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBF0894448.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10163..10807
                     /locus_tag="KNP54_003592"
     CDS             10163..10807
                     /locus_tag="KNP54_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0894449.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4446 a         1063 c         1763 g         3560 t
ORIGIN      
        1 aaataaatac aaaacaaaat aaataaataa taaaatattt agtttaatta tctttacaaa
       61 taaaaatttt agtaataaaa taattgttga aaaagatttt aaattcagat tattcatttc
      121 taaagtaatt aatgtgcaaa tctttattaa tatatgtcaa tagttaggta tatatgtatt
      181 taattagcat gatatagata aaagtattta ttttaattgt ctattatctg aaaaagtctt
      241 tacttagaaa tcataaaaat caaattaatt aggaaaagaa agggtgtgta taatgtgatt
      301 gagactggat ttgtatattg tagtttcttg gttgtattcg taggtgtaat tttttttatg
      361 gttgataaat tgaaatggaa ggtatttgat gttattaatc caatgctttt aatatactta
      421 ggttcagcta tacttggatc atttggttta tttgcacaga atgaagatgt tggaacgtat
      481 caaaacataa taacagtgaa cttccttcca ttaatgttag tgtttttgtt aattcaatgt
      541 gatttaagaa aaatattaaa gatggggcct aaaatgttat tatcattttt ctgtgctaca
      601 tttacattta tgcttggatt tgttatagca ttcataattt ttaaaaattc aatgggtgca
      661 gattcatgga aaattcttgg ggcagcatct ggttcatgga taggtggctc atcaaatatg
      721 attgcagcag ctaatgctct aggagttgca gaagaaggac ttagttatgc aatacttatg
      781 ggttctatag gatatacagt atggatgtct gtttgtctaa tgtctgtgaa atttggacct
      841 aaatttaaca aatggacaaa gtgcgataca agttttatag atgaggttac atcaaaactt
      901 gaaaaagaaa ataaagataa tacagcacct acgtttgtag aacttatgat tttactttct
      961 gttgggtttg gagttgcgtc ttttgcacaa attgtatcca agatacttcc aacttcaggt
     1021 atacttaatg aaactatgtg ggtagtactt gttgcatcta cagtatcaat attattgggt
     1081 atgacaaaaa tatcaaagct taaagggagt acactggtag gaaatgtgtt tatgtattta
     1141 ctccttgcag ctacaggtag taaagcaaat ttctttggat tgtcagaagc acctgtttac
     1201 ataatgtttg gattggtagt agtccttgta catgctattt catttatagg gcttgctaaa
     1261 ctatttaaac ttgatttatt tacttgtgaa gtaggaagta tagctaatat aggaggagta
     1321 actacagctc caatgattgc tggggttcac aatcctgtat taataccagt aggtgtactt
     1381 atggggcttc taggaaatat tatagggact tattgtgctc ttatggtaac tcaaatatta
     1441 catatgttag cttaataaaa atatggtata aaattaataa tttaaataag aaaagtcatt
     1501 tcaatttaag cagaagcttt tactgaaatg gcttttttgt ttgacaagat aatctatttc
     1561 aagaagatgt tttgacatat ttagtgtata atattgtaaa atttactaaa aacgagatat
     1621 atttaatttt tatattgaat cgaacgtctg tatgatgtat aataaatata cagaacgaat
     1681 gtttgcagaa cgggtgtttt ttgaatttat tttaataatt tatgaatata tatcagaatg
     1741 cataaatata tttaaatata aagattaaaa agaatttaaa ggagtgttga taacttatga
     1801 taattccatc aagaagaata caagatataa cattaacaaa tttaaaaaat ggtgaagtaa
     1861 ctttaattga attggatgaa atatacaaga agatgggatt tttatttgtt gttagtgaag
     1921 gcaaattgaa aaagataaaa aaggagaatc atcattagaa atgaatgaaa taataaatat
     1981 tataatagtt tataaaacct aacttatgta gaatataaat acttaagtta ggtttttttg
     2041 tgataaagtt tataagtact caattttata agataaataa tggtcttaag tgaaaagtaa
     2101 ataagtttaa attttagtaa gtattatatt gcataagagg tgatattatt atgaaaatag
     2161 taacctacaa tattcataaa ggtatggatt caaataatag attaactcta actaaaatgg
     2221 ggttatattt aaaacaattg gattgtgatg taatttgttt gcaagaagta ttatatcctc
     2281 aatttttagc tttaaaagct gttttaaata tggatggtgt ctttgcgaca aatgtaaaaa
     2341 aagtaaatat gatatatggt atttgtacat ttacaacatc taaaatgtta aacagtaatc
     2401 attttttctt aactagcaaa aaagaacaac ggggagctct ttgtataact atagatgcat
     2461 atggaagaat tataaatgta ataaatactc acttgggact tgataggcag gagagagcaa
     2521 aacaattaga cgaaataata gactatagga acagattagt ggggatagtt attttatgtg
     2581 gtgattttaa tgagaaaaat gtctttttaa gtatgtttaa tgatatggct atttcactaa
     2641 acaagtctta cttaccaaca tttgaaaaat caaactctag aatagattac atttttgtta
     2701 ataaaaatac tgaactaaaa ggatacacag tagaaaaaat ttacctgtca gaccattatc
     2761 ctgtaatagg ttacatttaa atttcaatat aaatgaaatt agttgttata aaataaacaa
     2821 ttttttgtta agaaatagta aaagaaatat aataaaaaat atcaaaaata aaactaatta
     2881 taagacataa atttacaata aagttacatt tgattaaatt ccttgtttaa caaaagctat
     2941 tcaaatataa tctaaggtag ttttgaaatg ggaactctat tatgcaaatt taagctagtg
     3001 ttaaaatgag gtgaagttat gggcagaaga acaacaagag tttcaagatt aggtaaagaa
     3061 aaaaaacgaa gtgttttaat tgtattggca gctttagttc taataatggg tggatttact
     3121 tattttttta acagtaaatt tctgtacaat gggaaaatcg ctaaaaatgt atatatagaa
     3181 ggagtaaatg tatctgatat gactaaagca gaggcattaa aagctataac agataagtat
     3241 actccagaag atttaaatct tgcttatgat gggaaaaaat atacaatatc accaaaagat
     3301 attgatttaa aatatgatac agaagatgtt gtaaaagatg cttatgaaag tacaaaaaaa
     3361 gggtcctatt ttcaaaactt aaaaaaatat attgatataa gagtgaataa ggcaaatatg
     3421 aagataaaag ctgaatatga tgaggcaaaa cttagttcca aagtgtcttc tatagcagat
     3481 agtataaatg ttaagatgaa aaatgcttct attagtgttg gaagtggtgg actaagttat
     3541 acagactctg ttgtaggtag agaatttgat ttggcagcaa ataaagagtc tatatataat
     3601 atgataaaaa ataaagagca taaaacttta gaacttaaag taaatcttca aaaaccagat
     3661 ataacaactg aacaagtaaa aactgtaaat tctgttatag gtcaatattc aactacttat
     3721 tcacaagctg tagagggtag gtcatataat gtaggattat cagcaagaaa aactagtgat
     3781 gtattattaa tgccaggtga agaattttca tacaataaac ttacaggacc tagtaataaa
     3841 gcaaatggtt acaaagatgc acctgttata gtttatggta agctagaaca atcagcagga
     3901 ggaggtgttt gtcaaacatc ttcaacagtt tataatgcgg ctcttctttc gggtatggag
     3961 ataactcaag ttacaaatca ttcatctgca tctacttatg tgcctaaagg gagagatgct
     4021 actgtgagcg atggaggatt aaacttaaag tttaaaaatc catataagca tcctgtatat
     4081 attaaaaatt atgcaggtgg aggaagtgta tcatcagtaa tctatggtaa ttctggtgac
     4141 aaaccaaata tatctataga ggtaaaacaa actggtcaga ataaatattc tacatatcga
     4201 atatttaaag attcaagtgg aaaggtcata aaaaaagaac atatatcaaa tagttcttat
     4261 aaagaattaa aaaaatagat aattttttag agaaatattt gtaatataaa agggagtgtc
     4321 tcaaaatgaa ctttttagtt tatgagacac tctttttctg tgaaatcaaa tatattttca
     4381 tcatttcaac aatacaaaag aagcgtatct ctattttgag acagcctttt ttgtaaaaat
     4441 taacactatt agttcttgtt ttaatattac aatcattaat atatagaaaa tattcctata
     4501 tattggtata attgtaaata gatttagtta tataaaatgt atgaggaggt gacatggttg
     4561 aattttatag gcaatagata tgaggtagta aattctgacg acgttttaga aattaacaaa
     4621 atctataaag ctagagatgt tttttacagg aaaaatgtgt taataaaagt tataaagcac
     4681 aataattata tctgtgaaga ttttgtttca aatttaattg atgaaagtac tgctttagat
     4741 gagataaact ctccttatat actaaaaata atagatgttg ggattcactg tacagaagaa
     4801 acaacattat attatgttgt aagtgaagac tttaatggta tcggactaga tgaattaatt
     4861 ctaggtaatt atcttcattt agaagcaatt gtaaacataa tgatacaagt tttaaaagct
     4921 ttagaaatga tacataggaa tcattcatat catggtagtt taaaatcgag tagtataata
     4981 gtagatacag aatacaatat aaaaatttgt gattttggaa ttacaaaagc aaataatggg
     5041 gttaatacaa gaagctatgg aaacaggaga tatttatgcc cacatcaact atgtataaat
     5101 tatactgata aagaaagtga tttttttgca acaggtctta ttctatttga atctatattt
     5161 aaaaaattgc cttttggaga atcaaattca gaagaaaaaa tgctacaatc tattgataag
     5221 ggattagatt ggaatagtat aaaagcaatt aatggaaata ctgaacttat aaatgttata
     5281 aaaaggcttc ttggaagaaa taataagtat actagagcca atgatattat tattgattta
     5341 agtaaagtaa tgtatgaaaa agcatatata gaagttgaag atgagaaaga agaagagcag
     5401 aaacaagaca aagttataca agttaaaaaa gaatataaaa gtaaaatgag aaaaaaatta
     5461 cataaaaaac ttgttgttgc cggtctagct atagtcatga tttcaatgat tattattagt
     5521 tccataatat aaaaattgta tattaagtat tttaaaatca atgtctataa aggatataca
     5581 tagaaatttt agtgtagtct taaattatga aaggaagtgg ttattatgtt aacaaaaaat
     5641 aatgaggtat taaacgtcta ggagtatttt aacaaatagc cacctgcttt tacagtttag
     5701 aataaaaaag ctgtggctaa aggtcacagc tttttgctac tttttaaagg caggagaata
     5761 ttaaaaagga gcaaattatg agcaatataa aaataatagc aagtaataaa tgttggattg
     5821 aagatatagc aaggaaacaa cttgaagata tttcaaagtt aaatggaatt ttaagagtag
     5881 taggattacc tgacttacat gcaggtaaaa tacctgtagg tttagcagtt gagactaaaa
     5941 atattattta tccacatata attggaaatg atataggatg cggaatgact ttatttaaaa
     6001 ctggggttct aaaaaagaaa tttaaaaaag acaaatggat taagtcactt agtaagatta
     6061 aagatttgtc tgatatagaa ataaaaaaca catataaaga agaatgtcca attttaaatt
     6121 taggaactat agggagtgga aatcattttg cagaaattca atgtataagt gaaatttata
     6181 ataaagaaca atttgaacaa ttaaaatttt catctgatga tattatgatg ttagttcact
     6241 gtgggtcaag aaattatgga gaagatattt taaaaaaatt ttatgataaa gatggacttg
     6301 aagttgaaag tgagaaagct atagattata ttaaaaaaca tgataatgct ttaatgtggg
     6361 cagagcgtaa tcgtgaagct atcagtaaaa aaattatgca gtcaataggt acatctggag
     6421 atgttgaaac aatattctct ataaatcata attttataga gaaaagggaa gataaattta
     6481 tacatagaaa aggtgctgtt tcaagtgaaa gaggagctgt gattatacca ggttcaagag
     6541 gcagtctatc atatatagtt atgcctactg aaaatacaga gatatcttta tattctctat
     6601 cacatggagc aggtagaaaa tggtctcgtt cagtttgtaa atctcgcctt aaaagtaagt
     6661 atagtaaaga tactataaaa caaactaaat ttaaaagtca gattatatgt aatgatgtaa
     6721 atttattatt tcaagaagct ccagaggcat ataagaatat agagcagatt attgaaagtt
     6781 tgatagaata tgaacttatt caagtagtgg caactatgaa gccattgatt acttataaag
     6841 gataattttt aaagttaaaa aagattaaaa ttatattata aatagctaat tttatggaac
     6901 atttaaaagt gttttattat tagctatttt tttattttgt agagacgata atttatagag
     6961 ctaaattctt tgatatataa tgattacaaa gttagactgt attggaaact gcacatacat
     7021 gaattgatga caatataagt gattcccaaa tataaatgaa agtataagct tatttttact
     7081 ataaaaattt tcactgtaca aaaacattaa tgacattatt tttattgaca taaatatata
     7141 atttatggaa taatattaga agcactgata taagtgttta aataagaata gaaaaggaga
     7201 agtgttttat gaaaaaaaat actaacatta atgagtccgg agttaaactt cttaataaat
     7261 aaggagtttg atatataata actccttatt tattaagttg ttcgcaaaat aactattatc
     7321 aaagtaaatg atagggtgat ttaaaagacg atgacttata aataaaggag aaaaaataat
     7381 gaatagtaat acatttgaaa gattacaact aaatgaagtt aaagacttaa taaaaataca
     7441 ttgtgtaagt tcgctaggaa aaaatttaat agataaatta actcctagtg ggaatattgg
     7501 agtagtaaga aggaaattag cagaaaataa agaagctaga aagataattg aaaatagtaa
     7561 tcacatacca cttgaaggat tgtttaatgt aggttctaca atagataaaa ttgaaaaagg
     7621 aatgataata gaacctgttg aacttgtaaa tattgaagat tttttaagag gttgtaggaa
     7681 gatgaaagct tttatgttag aaaaagaatt ttattcacct acattaagtt cttatgcctt
     7741 aaatataaca gaatgtaaaa gtatagaaga tgagataaat tactgtataa aatctaataa
     7801 agttgattct aatgctagta aagaattaaa aaagataaga cgaaatatag aaattacaga
     7861 aggaaagata aaagatagat taaataaatt tataacatca actgtaaata aaaagtatat
     7921 acaagagttt ataataagta aaagaaatga tagatatgta ataccaatta aatcttctta
     7981 taaaaatgaa gttaatggta ctatattaga tacatcatca aaaggaaata ctgtatttat
     8041 tgaacctatt agtgtttcaa atttaagtac agagttaact atgctaaaag ctgatgaaac
     8101 tattgaagaa tacaaaatat tatcttattt aacagaactt atatttgaga agataagtca
     8161 gataaaatta aatatagaga tactttcaga atacgatatg gtatttgcaa aagctaagta
     8221 tagtcaaaaa ataaaaggaa ttactccaaa aataaataat aatggctata taaaaataat
     8281 taaaggtaaa catccacttc taacaggaga tgcagtacct ttagattttg aaataggcaa
     8341 aaattataga agtcttataa taacaggtcc taatgcagga ggaaaaactg taacccttaa
     8401 gactgttggt ttactaactt taatggttca atgtggattt gatatttctg caaaagaagg
     8461 tagtgaattt agtgtatttg aaaaagtttt tgtagatata ggggataatc aaagtattga
     8521 aaatgcctta agtacttttt catcacatat aaaaaatatt gcagagatta tgagtttatc
     8581 aaataattct actcttgttc tgtttgatga aataggaagt ggaactgaac ctaatgaagg
     8641 agctggttta gcaatatcat tattagaaga gttttacaaa atgggatgta taactatagc
     8701 atcaactcat tatggagaga taaaaaagtt tgctacattg catccagaat ttgaaaatgc
     8761 tggtatgatg tttgataaag aaacgttaga accattgtat aagttaacta ttggaaaatc
     8821 tgaagatagt aatgctcttt ttatttctaa aaaaatggga ataaaaaata gagttttaga
     8881 tagagctaaa gaatatgtaa ttgatagaaa ctacaattta gatttagtta aaagaagtaa
     8941 gctacaatct aatattgaag ataaaaatag ttctgaagtc attttaaact atacagatta
     9001 taatgtaggg gataaggtaa aattactaga tgaagatgat tttggaattg tatataaacc
     9061 tatggacaag tttaataatg tagaagtatt gtttaatgat aattttattt cagtaaatat
     9121 aaaaagatta caacttagca taaaagcatc agaattgtat ccagaagggt atgatttaga
     9181 tgtattattt actagtttta aagaaagaaa attagaaaaa gatattcaaa gaggttcaaa
     9241 aaaagctctt aaaaagattc agaaagaaat tagagagaat agaaaataaa tataaaaagc
     9301 acaaaagaaa gcaatctaaa gagaaaagtt tatctttaga ttgctttctt attaacatat
     9361 cttcataaat ccaatgacta acaagattaa accacttaac caagataagt ttaaatttac
     9421 gtttttaaca aacatatttc ctagtaaaca accaagtaat actgcaatta tatttgatat
     9481 taaagaaaat agaataactt gtatataatt cacacctaca aggccactac caaaaccgat
     9541 agctaatcca tctaaactta aagcaagtgc aagtgtaaat gcttcagcag atttaagcac
     9601 tttagattta cttgtatcta agacatcagg ttcgatactt acattaaaat ttaatttaag
     9661 gtctaacata ttaaaattat aattctttga gtgtatagat tttttcttaa aataagattt
     9721 aaaaaaactt tcaattagtc tagcacttcc taataaaaat aaaataaaga aacatattaa
     9781 cattgttata ttttgaggta aaaagtctct aactattgta cctgcaaaaa gcgatattgc
     9841 taaaatagct gaacaaacta cgctgataat tatatttgaa tataagggaa ctttaacttt
     9901 atttacgcca tatccaaagc ttgtcacaaa ggcatctata caaagagaag taactaataa
     9961 aattgattca atcacagtag attaacatcc tttctcttaa attttgtact tatattagtt
    10021 atagtattgt aaaaatggat aaattgttac agataatcca ataaattgtt gataaaattc
    10081 caacatcata caacacctaa ataacaaaag aatcatatca tataataata taaaaccaat
    10141 cataataaag cgggtgaaaa taatggaaca aaataataag gttgggaatt tcggtgattt
    10201 gttgaagatt ttattagatg aaaaagaatt atcaatggga gaactaagta aaaaaagtgg
    10261 aattgataaa tctactatat ctcgtatagc taataataaa caaaagccaa atataaatca
    10321 tttagaaaag atggcaatac atttaaatat taacctagaa gaactgttga aagcttcagg
    10381 atatgaattt agaaacagca ataatcaaat atttaatgca gatagtgatt ttagtaactt
    10441 tgatgatatt cttggatttg caaatttaat caatgataag aactttaatg gaaatattga
    10501 aaaagagtta agtaagtgta agttatatgt ccaaacagat gaaggtaaaa aattactttt
    10561 tgataatttt aataaaaaaa tagattctat tgaaaaacaa ggtcaattta cagatagatt
    10621 aagacaaatg tatgctgatt tttgtacaga tggacttaca ataaagaaat atttattgat
    10681 tggaagtatg ctactttatt ttgttatatc aacagatgtg attccagact tcgtattccc
    10741 aataggattt atggatgatt tagtagcatt aaatatagtt acaaaattac ttaaaaatga
    10801 taagtaagtt ttagaatcat atttaatata ta
//
LOCUS       DAEHWO010000113        10721 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.116, whole genome shotgun sequence.
ACCESSION   DAEHWO010000113 DAEHWO010000000
VERSION     DAEHWO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10721
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.116"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            305..763
                     /locus_tag="KNP54_003593"
     CDS             305..763
                     /locus_tag="KNP54_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0894450.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            824..1099
                     /locus_tag="KNP54_003594"
     CDS             824..1099
                     /locus_tag="KNP54_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0894451.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1158..2432
                     /locus_tag="KNP54_003595"
     CDS             1158..2432
                     /locus_tag="KNP54_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBF0894452.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2562..3614
                     /locus_tag="KNP54_003596"
     CDS             2562..3614
                     /locus_tag="KNP54_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBF0894453.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3614..4645
                     /locus_tag="KNP54_003597"
     CDS             3614..4645
                     /locus_tag="KNP54_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBF0894454.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4737..5549
                     /locus_tag="KNP54_003598"
     CDS             4737..5549
                     /locus_tag="KNP54_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBF0894455.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5552..6472
                     /locus_tag="KNP54_003599"
     CDS             5552..6472
                     /locus_tag="KNP54_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBF0894456.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6647..7093
                     /gene="rpiB"
                     /locus_tag="KNP54_003600"
     CDS             6647..7093
                     /gene="rpiB"
                     /locus_tag="KNP54_003600"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBF0894457.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7123..7788
                     /locus_tag="KNP54_003601"
     CDS             7123..7788
                     /locus_tag="KNP54_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBF0894458.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7898..9400
                     /locus_tag="KNP54_003602"
     CDS             7898..9400
                     /locus_tag="KNP54_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBF0894459.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9712..>10721)
                     /locus_tag="KNP54_003603"
     CDS             complement(9712..>10721)
                     /locus_tag="KNP54_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBF0894460.1"
                     /translation="LAIVFLISIVVQAIIQYLVLIFFMYIYYAEAIAIVILFTLVNTV
                     FHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVIGDDEISTLAKSINNITGGLE
                     TAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDMLKNNDFDRETINDYINILDKK
                     SQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQSIVEFEDKIQNSSLDFIIETP
                     EYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDMFIKEENIILTFKNISNDKLN
                     LKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENAHMEIIIDADLFKVMLTFRRV
                     N"
BASE COUNT         4281 a         1219 c         1971 g         3250 t
ORIGIN      
        1 tataaaatag ttgttaaaca taaaaaacca tttgtaaaaa acaaaaaaat catttctcta
       61 acaaaaaaaa ccacaaaaaa tataaaaaag tatggctagt taagtgatta acaagtaaaa
      121 attaaaataa aaatcaaaaa aaatttatca atgaaagtca gctaaaatcc tggaagagag
      181 cattattttt gggaaaacat tttcttttgt ttcacaaaaa aagccacttt ttggcacaca
      241 acatgcttta tataaagtca agaaaaacta aggtataaga caaaggcaat taggaggtgt
      301 aaatatggag tttataaatt ttgtaagtga taaagttata gaccttaaaa tggattgtaa
      361 aacgaaagaa gatttcttta aagaaataca taataaagtt tttgatttag gctttgtaaa
      421 agaagaattt ggagaaaaaa tattagcaag agaaaatgta tttccaacag gtttaaattt
      481 aggtgattat ggagtagcaa taccacatac agatgcggaa tatattaaag agcaatttat
      541 atcagtctgt acttttaatg aaccagtagt atttagttct atggaagacc aagatgaaaa
      601 agtacctgta aatttggctt tcgtattagg acttaatcaa ccacacagtc aattatctgt
      661 attaacagaa ttaatgggaa ttatgcaaaa taaagagtta gttgataagt tgatgagttc
      721 tactgataaa gaagaagttt taaagacact aaagtcttta taaaaataaa aaagtactaa
      781 aaataaaaaa tataaaaata aaaattatta ggaggaaata aaaatgaaaa aaatattagt
      841 agcatgtgga gcaggaatag caacatcaac agtagtttgt gacaaggtag agagattagt
      901 taaggaaaat aatatacaag cagaagttat acaatgcaaa atagctgaat gtgcaacaaa
      961 gcaagaagga gcagatttaa tagtatcaac aactatacta ccaacaactt ataatatacc
     1021 agcaataaaa gcaacagcat atataactgg agtaaataca gcagcattag ataaaaaaat
     1081 attagatgct ttaaaataat cctatcatag atacattgaa ataatatttt ataaaacaga
     1141 aaaaggagga tttataaatg gataaattat tagcagtagt acaatacatt ttaaatatgg
     1201 gaccgacagt aatactacca ataacaattg tagtactagg aatgatattt agaattaagt
     1261 ttacaaaagc tttaaagtca ggtcttacaa ttggtatagg atttgtgggt ataaacttag
     1321 ttgtaaacct attaacatca acactagggc cagcggctca aggaatggtt gaaagattcg
     1381 gacttaattt aacagtaata gatgttggtt ggccaacaac agcatcagca acatgggctt
     1441 caccagttgc accaatatta ataccagttt gtttattagt aaacttacta ttattatact
     1501 tcaataaaac aaagatatta aacgttgata tatggaatta ttggcacttt atagtagcag
     1561 gtgcagttgg atatatagta acaggaagtt atgtttgggc tatattctgt gcaatactaa
     1621 tggagttatt agtactgttt attgcagaaa agacagcaaa aaatgttcag gagttttatg
     1681 atttagaagg tatagcatta ccaactggtt caacagcttc atttgctcca cttggatatt
     1741 tagtaggtaa atttgttgaa aaaataccag gaataaataa aatacaagca gacccagact
     1801 ctatacaaaa aagatttggt atatttggag aaccaatgat gatggggatt atactaggta
     1861 taatacttgg agcacttgcg ggatatgatg tagcaggaat attcaatgta ggtatatcaa
     1921 tgggtgcagt aatgttactt atgcctagaa tggttagaat attaatggaa ggtttaattc
     1981 caatttcaga atcaataaga gatttcttac aagcaaaata tggagacaga gaactttata
     2041 taggtctgga tgcagcagta gcaactggac atccagcagt tatatcaaca gctcttatac
     2101 ttgttcctat aactttgttc ttagcagtta tactaccagg aaacaaagtt ttaccatttg
     2161 gagacttagc gacaatacca ttttatatgg catttatagt gtgttttaga aaaggtaata
     2221 tagttcaatc agttataaca ggaacaatag taatagctat atcactttat atggctacaa
     2281 actttgcaga tgttcataca caattattac aacaagcaaa tatgatgcca gaaggaacaa
     2341 caatggttac aagtatagat acaggtggaa acttgctaaa atggggaata ttgaaattat
     2401 ctcaattagt ttcttcattt ggaatattct agtatgtagt taatagagat tactcttttt
     2461 tagtaaagta tgcgaaaatt taacatttag cagctactaa aaaagagtaa tattttttat
     2521 aaatttttaa aaatacaaaa tacaagagga ggagatttat cgtgaaagca gcagtattac
     2581 atggcacaaa tgatatgaga tttgaagata tagaaataaa accatgtgaa agtgatgaag
     2641 taaaaataaa agttatggca gcaggaatat gtgggtcaga tcctccaaga gtattaaaac
     2701 attggaaata tccagttcca gctataccag gacatgagtt ttctggagta attgctgaag
     2761 ttggtaagga tgtaaaaaat gtaaaagttg gagatagagt agttgcaatt ccttttatac
     2821 cttgtaatga atgtgaatat tgtaaaagag gattattttc attgtgtgat gaccatggaa
     2881 tgttaggagc taaaagtttt ggagcttttg cagagtatgt aaatataaaa gctacaaatg
     2941 tacttccaat aggagatatg aactttgaag atgctgcaat gatagagcca ctagcagttg
     3001 ctatgcatgg agtacttaat ataggtgttc aagttggaga cactgtagct gtaatgggta
     3061 gtggaacaat ggggcagttg gtaatacaag gacttaaaat agcaggggca ggaacaatta
     3121 tagcagttga tatatctgat aataaattaa gagaatcaaa ggaattaggg gctgatataa
     3181 taattaatgc taaagatatt aacccagtag aaaaaataaa agaacttact ggtggaaaag
     3241 gtgttgacat agctcttgaa tgtgcaggtt caaaaataac tcaagaacaa tgtttactta
     3301 taactaaaaa gaaaagtaag ataggatttt tagggatagc atattcagat ataactttat
     3361 cagaagaagc atttgaaaat atatttagaa aagaactaga attaaaaggt ttttggaact
     3421 cttattctgc accatttcca ggacaagaat ggactaaggg aatcaatcta gttaatgaag
     3481 gaaagataaa attaaaagaa atggtatctc atagattctc acttgaagat acttacaaag
     3541 catttgaaat gataagagat agaaaagaag aatttaacaa aatattaatt ttaccacaag
     3601 gggttgaaaa ataatgaaag cagtagttaa aactaaacca ggctatgata atgtagaagt
     3661 tttagaagta gaagaaccaa aagctacagg agacaaggtt aaaataaaag tagaatatag
     3721 tggtatatgt ggttcagata tacattcatt taaaggtgaa tatgcaaata taaaagcccc
     3781 agtaacatta ggtcatgaat tttctggaat tgttgtagaa gtaggagaag atgttaaaaa
     3841 tataaaagta ggagatagag ttacatcaga gactactttt gcaacttgtg agaaatgtat
     3901 atattgtgaa actaaagatt ataacttatg cccaactaga aaaggtattg gtactcaagt
     3961 aaatggaagt tttgctgagt atgtattatc aagagaagaa agcatacatg tacttcctga
     4021 aaatgtatct ttattatcag cagcccttac agagccacta gcttgttgtg ttcatgcagc
     4081 tcttgaaaag actactatag aaagttctga tacagtttta ataataggac caggaccaat
     4141 tggtttatta ttagctcaag ttgttaaatc tcaaggtgct acagttataa tgtctggtgt
     4201 tacaaaagat aaggaaagat tagaaatagc taaaaatctt ggagtagata gaactgtaaa
     4261 tgtaatggaa gaaagtttgg cagatgtagt gaatgaaatg actgatggaa atggagtaaa
     4321 caaaggattt gattgttctg ggtttatgcc agcagttaac gaagccttaa gactgcttag
     4381 aaaaaaaggt actttcgtac aagttggaat ctttgctaaa aaattaaatg aaatggacca
     4441 agaagcaata atccaaagag agttacaata tataggaagc aggtctcaaa agccaagttc
     4501 ttggattaca gcattagatt taatggcaaa tgggaaagta aatacagaag ctttagttac
     4561 tagaactgtt ggtttagacg aatttaaaga aggtattaca gctttaatga acggggaaga
     4621 aataaaagta gcagtaaaat cttaaaaaaa catttgtatt attttaaaaa aaattgtaaa
     4681 atctactgta ggataaaaaa atgtaaggtc ttaaaaaata acaggaggaa gaaagtatga
     4741 gcactcttag agatcattct aataatatta gaaaaaacat aataaaaatg gttgcagaag
     4801 ctaaaagcgg acatccaggt ggttcattat caatagctga tatgttgaca gtattatatt
     4861 ttgataagat gaacgtatgt gcagaaaatc caaaaatggc tgatagagat agatttgttc
     4921 tatcaaaagg tcatgcagca ccagctttat atgctacatt agcagaaaaa ggatttttcc
     4981 cagaagaaga attaataaca ctaagaaaat ttggttctaa gttacaaggt cacccagaca
     5041 tgaaaaaagt agcaggaatc gatatgtcta ctggttctct tggtcaaggg ctatctgcag
     5101 caaatggtat ggcacttgca ggaaaattag ataacaaaga ctatacagta tatactatat
     5161 taggtgatgg agaaatccaa gaaggtcaaa tatgggaagc tgcaatgaca gcatcacatt
     5221 acaaattaga taatttaatt gcatttgttg acttaaatgg attacaaata gatggttcta
     5281 atgaagaagt aatgaatgta agtccagtag atgacaaatt caaatctttt ggatggaatg
     5341 taatagtaat aaatggacat tcttttgaag aaataggaaa tgcagttgat gaagctaaaa
     5401 aagttacagg aaaaccaact gtaataatag ctaaaacagt aaaaggtaaa ggtgtttcat
     5461 ttatggaaaa taatgctgca tggcatggaa cagctccaaa tgcagaacaa gcagagcaag
     5521 cattgaaaga tttagaagga ggtctatagg aatgggaata gcaactagag aagcttacgg
     5581 acaagtgtta aaagaacttg cagaaaataa agatatagta gtattagatg cagatttagg
     5641 aaaagctaca aaaagtatat catttaaaga agttgcccca gatagatttt ttgacatggg
     5701 gatagcagaa ggtgacatga ttggtacagc agcaggtctt gctacttgtg gaaaaatacc
     5761 ttttgcgagt acttttgcaa tatttgcagc aggaagaggc tatgagcaaa taagaaactc
     5821 tgtagcatat ccaaatttaa atgtaaaaat agcagctact catgcaggtg taacagtagg
     5881 tgaagatggt ggtagccatc aagctataga ggatatatct ctaatgagag gtataccaaa
     5941 tatggttgta ttaaatccag cagatgcttt agaagcaaga caagctattc ttacatctat
     6001 tgattataat ggacctgttt atataagatt aggtagagct gcaactcctg atgtaaacag
     6061 tgaaaattat aaatttgaaa taggaaaagg aactgtttta agagaaggtt ctgacataac
     6121 agtaatagct acaggaataa tggtagcaaa agccttagaa gcagcagaag aacttgctaa
     6181 agaaggtata aatgtagaag ttgttaatat atctacaata aaaccattag atgaagcatt
     6241 aataaaagaa actgctaaga aaactggaaa agtagttaca gcagaggagc acagtataat
     6301 aggtggttta ggttcagctg tatgtgaagc tttagcagaa actaaagatg tagtagttag
     6361 aagaattggt gttaaagatg tatttggtca atcaggtaca ccagctgatt tattaaaaca
     6421 ctatggttta actacagaag atatagtaaa aaatataaaa gagttgttat agatataaat
     6481 atatctaaat aacaaattga tttgacataa gtcaattaaa gctgtcttaa aaatagaaag
     6541 aaatttctac aatgggacag ctttattttt acaatacttt atttttatga taattataaa
     6601 atagtctgaa agtaatcaaa aaaattataa aaagaggtgc tatttaatga aaatatctat
     6661 tggatgtgac catggtggtt atgaattaaa ggaatatata aaggaaaatt taataaataa
     6721 aggtatagaa gttgaagatg tgggtacaaa ttcaaaagaa agtgtagatt ttccaatata
     6781 tgcaaaaaag gtaagtcaaa atgttcaaag taaaaaatct gatttaggca tactttgttg
     6841 tggaacagga ataggtatgt ctattgcagc aaataagttt aaaggaatca gagcagctgt
     6901 tgtttctgac tgtttttcag ctaaggcaac tagagaacac aataatacaa atgtactttg
     6961 tttaggagaa agagttattg ggaaaggatt agcaatgaga attgttgaag aatggttaaa
     7021 ttcaagttat aatggagaaa gacatgcaag aagattacaa atgattgatg atatagaaaa
     7081 agaaaattta taaatatata atttataaca agggggagcg ttatgtctat tatttgtgct
     7141 tcaataatgt gtgcagacca aatgaagtta aaagaggaat tagaagctct tgaagaagca
     7201 ggtgtaaaat tacttcattg tgatgttatg gatggaatat ttgttaaaaa cttggctatg
     7261 ggaccagagt tattaaaatc aataagtgaa aatacaacaa tacctttaga catacactta
     7321 gccacagaaa ctccagataa atatattgat atgatgtctt atataaagcc aaaatatatt
     7381 tcttttcatg tagaatcaag tacaaatgta aaagctgata tacaaaagtt aagaaattat
     7441 ggtatagggc cagtgttagc aataagccct caaacaagtg tggataaaat agaagaatat
     7501 ataagtttag ttgagggtat cttagtaatg acagtaaatc cagggtttgc aggtcaaaag
     7561 tttaatcttt ctgtattgga taagttggat aaacttacag agatactaaa agattatgat
     7621 aatcctccat ttatagaggt tgatggaaat ataaataagg atactattaa acttatgaat
     7681 ggtaaaaaag tagatatata tgttgttggt acttcagctt tatttaatga taagcctcca
     7741 atttcatata aagataaaat agaagaacta aaagaaagta taaagtaacc atgtaataaa
     7801 attataatat gtttctgttt aatagtaaaa atttaggtgg aaacaagaaa ttttataata
     7861 tttaataaaa attttggttg agtaaggaga attttttatg ggagacctat ataaactaca
     7921 aaatggtact gatattagag gaatagcgta tgaaaatgat tctaaagaag ttaacctaac
     7981 tgtagaagaa gtaaaaaaaa tagctaaagc gtttcatatt tggttaaaag aaaagactaa
     8041 gaaagataaa gtaactgttg ccataggaac tgattctagg ataacaggaa gccaatttag
     8101 aagtactgtt attgaaactt taactaatga cgattgtaat gtaattgatt gtgagattgc
     8161 cacaactcca gctatgttta tgacaactat tatggatgga tacaattctg atggggcgat
     8221 tatgattaca gcaagtcact taccttatta ctataatggt ttaaagtttt tcacagaaag
     8281 tggaggttta gaaaaaactg atataaaaga gatgttggat atagctgtta aaaatgatag
     8341 tgtagactat gaggaagtaa ataaaaaagg tgaagttata gtaaaaaatt taatagaaga
     8401 ttattctaat ttattgatag ataaaattag aaaaggtgta aattcaagta aaaattatga
     8461 aaagcctttt tctgggctta agatattggt tgatgcagga aatggggctg gtggattctt
     8521 tgctgaaaaa gttttacaca tactgggagc agatacgaca ggtagtcagt ttttgaaccc
     8581 agatggtatg ttcccaaatc atatacctaa tcccgaaaac aaagaagcaa tggaaagcat
     8641 atgtaaagct gtgttagata ataagagcga cctaggaata atctttgata cagatgtaga
     8701 cagagctgct attgtaggta aaaatggcaa accaataaat aaaaatgctc ttatagctgt
     8761 tatatcatca atagtattag aagaacatcc aaaaacagct atagtaacag attcgattac
     8821 ttctgaagga cttgctaaat ttataaatga attacaagga agacatcata gatttaaaag
     8881 aggatataaa aatgtaataa atgaagctat aagattgaat agtgaaggtg aagagtgcca
     8941 tttagctata gaaacgtctg gacatgctgc tttaaaagaa aattatttct tagatgatgg
     9001 ggcatattta atagctaaaa ttttaataaa agtagcaaag ctatccttgg aaggaaagac
     9061 tatagaagaa ttgatagaaa accttgaaga agctcaagaa gagaaagaag ttagaatagg
     9121 cattaataaa gaagatttta gaccatatgc agaggatata ttaaaagatt tagattctca
     9181 tgtcaagagt attgatggat ggtctgtagc accaaataat tttgaaggca taagagttaa
     9241 ttgtgatgaa tcaaatggag atggatggtt tttacttaga atatcactac atgaaccatt
     9301 attagcttta aatattgaat caaataaaat tggcggagca gaacaaattt attctaagtt
     9361 aaaacttttc ttagaaaaat atgatttaaa aggtctttag ggtaaataga aagaatatat
     9421 ttatattgaa gaataaatgt aaatttgtac ctaagattac aaatattaca aaattgtaat
     9481 cttaggtaac agagatgtaa ctgattatgg aaacactatg tgatattata gatacagaga
     9541 gatgaaatat gtgatgaatt atagagaaat ataatttaaa atgtattaat atcacaccaa
     9601 aaaggtataa tcaaaaaata tgtaaatata aaccccaaca tttagaagaa gacctctaag
     9661 gaggtttttt tcttgtttaa ataacttaaa atatattttt atatcaatat atcaattaac
     9721 tcttctaaaa gtaagcatta ccttaaataa atcagcatct ataattattt ccatgtgtgc
     9781 attttctaat tcaattatat tttgagcaat tgataaacca agaccagagc catctgtttt
     9841 tctagatata tcaccccttc taaatctttc tattaactct tctggcttta gatttagttt
     9901 atcatttgaa atatttttaa acgttaatat tatattttct tcctttataa acatatctat
     9961 gtagacccta gtgttaggca tagagtattt tagtatattg caaattagat tctcaaaaac
    10021 tctccaagtt tttttaccat ctatcatggt aaaaacagca tattcaggtg tttctattat
    10081 aaaatctaaa ctgctatttt gaattttgtc ttcaaactct acaatacttt gaattaaaag
    10141 ttctcttata tcggtttttg ttatattaaa ttctacatct ccactactta gcttagatgc
    10201 ttcaaatatg tcatctatta ataattttaa tctttgtgat tttttatcta aaatatttat
    10261 atagtcattt atagtctctc tgtcaaagtc attatttttt aacatatcaa catagcttaa
    10321 tatagatgta agtggagttt ttaagtcatg agatacgttt gtgataagct ctgccttcat
    10381 cctttcattt tttatattag catctacagc agtttcaaga ccacctgtta tattatttat
    10441 acttttggct aaagtagata tttcatcatc tcctataact tctaatttat actttaaatt
    10501 gccattttct atatttttta tattttttga tatgttattt atgtaattaa acttaacaga
    10561 taaaaagttg tatatataaa aatgaaaaac tgtgtttaca agtgtaaata aaattactat
    10621 agctattgcc tcagcataat atatatacat aaagaatatc aaaacaagat attggataat
    10681 agcttgtaca actatagata ttaaaaatac tatagctaat t
//
LOCUS       DAEHWO010000114        10695 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEHWO010000114 DAEHWO010000000
VERSION     DAEHWO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10695
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.117"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            201..1385
                     /locus_tag="KNP54_003604"
     CDS             201..1385
                     /locus_tag="KNP54_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894461.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1762..2871)
                     /locus_tag="KNP54_003605"
     CDS             complement(1762..2871)
                     /locus_tag="KNP54_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBF0894462.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3334..4527
                     /gene="nifV"
                     /locus_tag="KNP54_003606"
     CDS             3334..4527
                     /gene="nifV"
                     /locus_tag="KNP54_003606"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBF0894463.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4552..6477
                     /locus_tag="KNP54_003607"
     CDS             4552..6477
                     /locus_tag="KNP54_003607"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBF0894464.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6499..7494
                     /locus_tag="KNP54_003608"
     CDS             6499..7494
                     /locus_tag="KNP54_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBF0894465.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7819..8292
                     /locus_tag="KNP54_003609"
     CDS             7819..8292
                     /locus_tag="KNP54_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBF0894466.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8326..8820
                     /locus_tag="KNP54_003610"
     CDS             8326..8820
                     /locus_tag="KNP54_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0894467.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8917..9438
                     /locus_tag="KNP54_003611"
     CDS             8917..9438
                     /locus_tag="KNP54_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBF0894468.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            9627..9938
                     /locus_tag="KNP54_003612"
     CDS             9627..9938
                     /locus_tag="KNP54_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBF0894469.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9966..10652
                     /locus_tag="KNP54_003613"
     CDS             9966..10652
                     /locus_tag="KNP54_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBF0894470.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
BASE COUNT         4088 a         1165 c         1941 g         3501 t
ORIGIN      
        1 ttaaaaaaca aagtgaattt gaatactatt taaaaaataa aataaatata taaaaaatat
       61 ttaatataaa ggtggaaata agttgaaaat gtaaagtcat tggaaaaata tagttgaatt
      121 taatgagcaa aaatgttatt gttttatcaa taaagtgtta aaataaaaac tttcaatatc
      181 attttaggga ggatgatttc atgcaaaaaa gtgtaaagaa agcaaaagta acgggctcta
      241 tgttagctat ttttggtgtt gcaagcgttc tttttagttc acatgcagga ggaggatttg
      301 ctacagggaa tcaagaaact cagtactatg tgcagtatgg atggacagca ccacttatgg
      361 caattttagc aatgattata cttactgcta ccatgagaga agttatcata atgtataata
      421 ataacaattg taggaattat aaggatttat tttgtgagct ttggagacca tatccaaaac
      481 ttgaaataat atgggagata tattactatc taatggtttt aatagctgta agtgctgtta
      541 tagcaggtgc agcagcagta tttcaaagta taggagtaaa ttattttgta gctgtattta
      601 ttattggagt tgtacttctt gtctttacta tatttggtgc tatgcttgta tctaaagcag
      661 ctacagcaat gacaatagct attctagtat gtactcttac tatttttatt gttggtataa
      721 aagctaaagt accagaaata actgaaatat tatcaaatag aacgagtttc acacctggct
      781 atatcaagcc aatacttaat acttttattt atgcaggttt tcaatcggtt gttataccta
      841 cacttgcagg atgttcaaga ccacttctta agaactcaaa agaagctact aaggcaatga
      901 taatttcatt tgttatgaat gcaattgcat taggacttgc tgtaactatg ctaatgggat
      961 ggtatagaga aattattgct gctgggcaaa caacactccc tactctttat gttgcaggtc
     1021 aatctggaaa tcatactata tacataattt ataatgttgc attattcctt tgtttaatgt
     1081 ctacaggagt aactactata tttggtcttg taaatagatt tgaagaccat aaagcacttt
     1141 ctttcctttc ttcaagaatg aaaagaaggg tatttacagc ttgtgcaata atggtagtgt
     1201 caatgcttat atcacttaca ggattaagta atattgttaa atatggatat ggatattgtg
     1261 gttatcttgg tctattcact atagtaattc catttcttac actaggacat tataagaata
     1321 agaagtttgc aaaggaaaat ccagaagcta aatggccagc ggaattaaat gaaaatgtaa
     1381 attagatgta gtagcaaaaa atattgctaa agagaatact ataaataaga atactataga
     1441 taatatatct gcatgtttat taagattatt tgcaaaatct aatattaaac aactataaac
     1501 aagcaatata aaactaagaa taaaagataa aaagagggta tctcaaaatg gacttttagt
     1561 ttataaggca ctctttttta tatgaagtca aatatatttt cattattttg acaataaaag
     1621 agactaatcc tactttggat agcctctttt ttctttaata taaaatagta taacagcaaa
     1681 gtatagattg atacatgttt tctgtagctt tctatatatt acagtgtttg tgtggcattg
     1741 gtattttaag caatctataa attataattc tataattctt ctactaattt tagattctat
     1801 agccgtctct atttcactta acattcgttc atttttaggg tcaataaaag cacatgtata
     1861 gccttcttca ccagctctac cagttctacc aatacggtgg atgtagtctt ctggtgtttc
     1921 tggtaaatcg taattatata tatgacttac tccagatata tcaagaccac gagaagctac
     1981 atctgtagct attaagtatt gtatatctaa atttctaaat gatttcatta ttctttctcg
     2041 ttttgattga gcaatatcac tatgaagttt ttgacaatta tatcctctta tagcaagagc
     2101 ttcttcaaga ttgtcaaccc ttctcttagt tctacaaaat attattgcca taaaaggatt
     2161 atcttcatct agtaccttac ataaggcatc taattttttt ctatctgtag tttctactac
     2221 ttcttgtttt atattattaa gagtgatttc ttctttttga atagaaacta caacaggatt
     2281 ttttgtgtat ctataagcta atttttttac ttgagaattt atagttgcag aaaagcatag
     2341 tgtttgcttt ttgtttgaag tctcttttaa aatagcttcc acttcatttt taaatcccat
     2401 aagcaacatt tggtctgctt catctaaaac aaaagtcttt aacttactaa ggtctattgt
     2461 ttttctattt agatggtcta aaagcctacc tggtgtagct ataatcatat gaatatttcc
     2521 ttttagtttc tttatttgag aaccaatatc ttttcctcca tatgctgcaa gaatacttac
     2581 atctttagat tctttaagtt tcatagcttc ttctgttatt tgaatagcta gttctcttgt
     2641 aggagaaagt ataagtactt gtatatcatt tatatctaat gatatatttt caaatatcgg
     2701 aagtaaaaaa gctagtgttt ttcctgttcc agtttgagct tctgctatta catcttttcc
     2761 ttcttttatt agtttaatac tttctttttg tataggtgta ggtgttgtta ttcctgattt
     2821 ttttagaata tttattgtat tttcactaat ccctaagctt ttgaaatcca ttgttatctt
     2881 acctttcatg aaaaattttc ttttttatta accaattaat aatatcatat ttgtaagtat
     2941 ttttagtaaa ttttttaatt attatttata tagcttaaaa atatattaag atactttaaa
     3001 atggaatgta acttaaatta aattttagta ggaattttat aggtttattt ttaaaggttt
     3061 tttgaaaata aatctattta aaaattaaat taaaatgcaa gaaaaacata ataactttca
     3121 tttttaagaa gttttcacaa aaaagaaaaa atatagtgca ataaatgata caaagtaata
     3181 taatagatta caagatatga aaagctaaaa aaataaattg caaatgaaat taaaatgaat
     3241 aaaaaataaa aaaataatca taagttagaa gtatcaatga aaaataagac ttaatgtttt
     3301 taaaattaaa agtatactaa ggggggcatt aatatgtgcg ttatatcaaa agatagagca
     3361 aaggaaataa aaatagtaga tactacttta agagatggag agcaaacagc tggggttgta
     3421 tttgcaaata gagaaaaaat aatgattgct gaaatgttaa gtgacctagg tgttgaccaa
     3481 attgaagttg gtatacctac tatgggtgga gatgaaaaaa atgtaataaa gcacatatgt
     3541 agtagaaatt taaaatcaga tataatggct tggaatagag cagtaataaa agatgttgaa
     3601 gaatctattt cttgtggtgt tgatgcagta gctatatcaa tatcagtatc tgacattcat
     3661 atagaaaata aattgagaac ttctagaggc tgggttttag aaaatatggc taaaacagtt
     3721 gaatttgcaa agaaaaatgg attatatgtt tcagtaaatg gagaagatgc ttcaagagca
     3781 gatatagact tcttaactga atttataaat gttggaaaac aagcaggggc agatagattt
     3841 agatactgtg atacagtagg agttatgaat cctttttcta taaagaatgc aatagaaact
     3901 ctttatgaaa gaactaattt tgatatagaa atgcatacac ataatgactt tgggatggca
     3961 actgcaaatg cacttgcagg aatagcagca ggagcaaatt atgttggtgt tacagtaaat
     4021 ggattaggtg aaagagcagg aaatgcagca ttagaagaag ttttaatggc acttaagtgt
     4081 gtttataaat gtgatttaaa taatatagat actagaaaat ttagaggaat atgtgagtat
     4141 gtagcacagg catcaggaag aatacttcct acatggaaac cagtagttgg ggataatatg
     4201 tttatacatg aatctggtat acatgcagat ggagctttaa aagacccaca taactatgaa
     4261 ccatttgacc caagtgaagt aaatcttgaa agaaaaatag taataggtaa acattcagga
     4321 agagctgcag ttgtaaataa gttgagtgaa tatgaaatgt atatttctcc agaaaacgct
     4381 accaagctat taaatgctat aagagctaca tctataagat taaaaagaag tttaatggat
     4441 aaagaaattc ttcaattata ttgtgatata ctagcacatg agaaaggcac aacagaagaa
     4501 gaagcagtta gaggttcata tatttaagat ataattgttt aggaggaaaa tatgggagat
     4561 aatatagttt ataaaataat taaaaaacat atagtagatg gagaagctgt tgctggaagt
     4621 tcaattggta taaaaataga ccaaacttta acacaagatt ctactggaac aatgacatat
     4681 cttcaactag aagctatggg aatagataaa gtaaagacta aaagaagtgt ggcatttgta
     4741 gaccataata tgttacaaca aggatttgaa aatgcagacg accataagta tatacaaaca
     4801 gtggcagata aatatggagt ttatttctct aagccaggaa atggtatttg tcatcaagta
     4861 tttttagaaa gattttcaac accaggagat acacttttag gttctgatag ccacacacct
     4921 actgctggag gtgtgggcat gatggctatt ggagctggtg gattagatgt tgctttagcc
     4981 atggcaggag gagcatacta tataaaagca ccaaaagtct gtaaggtgaa tctagttgga
     5041 aaattaaata atatggtatc atcaaaagat ataatattag aagtgttaag aaaacaaact
     5101 gtaaaaggtg gagtaggtaa agtttatgaa tatggtggag aaggtgtcaa aagcctatct
     5161 gttccacaaa gagctacaat aacaaatatg ggggctgaac ttggagcaac tacttcaatc
     5221 ttcccaagtg atgaaaaaac actagaattt tttaagagtc aaggaagaga agacgcatgg
     5281 gtagagctaa aaccagatgc agatgcagtt tatgatgaag agattactat aaacttggat
     5341 gaattaaaac cattagctgc aaaacctcat agcccagaca atgtagatga agttgaaaat
     5401 ataggcaaga ttaaaataga ccaagtggca ataggaagtt gtacaaattc ttcttatgaa
     5461 gacttaatga aagtagcaca aatcctgaaa ggaaataaag tacataagga tgtgagtttg
     5521 gtaatagcac caggttcaag acaagttatg gagatgattg ctagaaatgg ggctttggca
     5581 gatataataa gtgctggagc tagaatacta gaaaattctt gtggtccatg tattggtatg
     5641 ggtcaatctc caggtactga ctctgtgtct ttaagaactt tcaatagaaa tttctatggt
     5701 agaagtggga ctttgtcagc acaagtatat ttagtaagtc cagaagtggc agcagtaagt
     5761 gcaatcaagg gagtgcttac agacccaaga gaatttgata ttaaatttac aaatttagat
     5821 gtaaatgagt ttttgataga tgatagcatg ataattaaac ctgctgatgt aggaagtgat
     5881 gtagaagtag ttagaggacc taatataaaa cctttccctc ttaatacaga gctaagtcag
     5941 tctataggtg gaaaagttat attaaagaca gaagataata taactactga ccatataatg
     6001 ccatcaaatg ctaagttact tccttttaga agtaatatac cgtatcttgc aaactattgt
     6061 ttcaatactg tagatacaga atttcctcag agagcaaaag acaataatgg tggatttata
     6121 gttggtggag ataattatgg tcaaggttca agtagagaac atgcagcttt agcaccatta
     6181 tatctaggtg ttaaaggggt aatagttaag agctttgcaa gaatccacaa ggctaacttg
     6241 ataaatagtg gtataattcc aatggagttt tgtgatgaga aagattatga aaatatatct
     6301 cttttagata atctggagat accaaatatt ttagacaatc taggtagtgg aattttagaa
     6361 gttaagaata caactaaagg aacttctttt aaggtcaaag tagaattgtc agcaaaagaa
     6421 gttgatgtat taaaagctgg tggaaaatta aactacacta aaaatcaagc taattaatat
     6481 gaaaagaggg aatattgaat gtataaagtg acacttatac caggagatgg aataggacca
     6541 gaagttgcga aagctatgaa aaaggtagta gaagctactg gagtagaaat agaatgggaa
     6601 gaagttaatg caggagaggc agttattgaa gagtatggta ctccacttcc tgaatatatt
     6661 atagatagta taaaaaagaa caaaatagct ataaaaggcc caattactac tcctgtaggt
     6721 aaaggattta ggagtgtaaa tgtaacttta agacaggcat tagatttgta tgtcaactta
     6781 agacctatta aaagttttaa ggggataaaa tcaagatatg aagatgttga tttagtggtt
     6841 gtaagagaaa atacagaaga tttatatgct ggaatagaac ataaaatagg tgattatgca
     6901 gctgaaagta taaagataat aacaagaagt gcaagtgaaa gaatcgttga ttttgcatgt
     6961 aactatgtta aagataataa gagaaaaaaa gttacagcta tacataaggc aaatataatg
     7021 aaaatgtctg atggattgtt tttagatgtg tttagagaag ttgcatcaaa acatggtgta
     7081 gaatatgatg atttgattgt agatgcagca gctatgaact tagttttaaa tccagaaaat
     7141 tatgatgtaa tggtaatgcc aaatctttat ggagatatac tatcagattt aggtgctggg
     7201 cttgttggag gtttaggtat aattccaagt gcaaatattg gtaaagattg tgcgatattt
     7261 gaagctgttc atggaagtgc tccacaaata gcaggtcaaa ataaggctaa tccaacagca
     7321 cttattcaat catcagtaat gatgcttaga tacttaggtg aatatgaaaa tgcacaaaaa
     7381 atagaaacag ctttagaaaa agtatttctt gaaggaagta aattgactgt agatttaggt
     7441 ggctcagctt ctactacaga gtttgcggat gaggtgtgta agtatattgt atagatttta
     7501 tttagggaaa aagtaaaata tagattgaag aaaagaggct ttctcaaaat agagataagc
     7561 cttttttatt ggaatgataa aatatatttg attttataca aaagagagtt cctcataaac
     7621 gaaaaagtta attttgggat atccatttta attttaaaat taattgatta atacgcaaag
     7681 aaagattaaa taaatttatt atttttaatt gaactttcaa ccaaaatatg gtaaaattta
     7741 aaaagttgaa ctttcaacta aaaatgaaaa tattgattat gtgaaattct ataaaacaga
     7801 aactatttga ctttagccat ggtagtttca gtggaggtgt gtttgattaa gactttagat
     7861 agtaatatat taagagaagt aggtacttta tctagagcag taaattcaat aaatgatatt
     7921 aagtacaagg aattaaagtt acaaaaagga caatttacat ttttgacaag aatctgtgaa
     7981 aatcctggta taaatcttgt ggaattatca aatatgttaa aggtagacaa ggctacaaca
     8041 accaaggcta tacaaaaatt aataaaggca ggatatgtag ataaaaagca ggataagttt
     8101 gataaaagag gatataattt aactccaact gataaatctt tggaagttta tgagttgata
     8161 attgaagaag agaatagaag tatagagata tgttttgata attttacaga tgaagaaaaa
     8221 caagtggtaa ctaagttatt agaaaaaatg agcaaaaacg tagaaaatga atggtttaaa
     8281 gtaaagagat agtaaataaa tacattaact taaggagata tttttatgat tagaaaagcg
     8341 aatatgaatg atttagaaag cattatgaaa attataaaat ctacagtgga agaaatgaag
     8401 acttataata atacacaatg ggatgaaaac tatccattag aaaaagactt tgtttcagat
     8461 attaagaaac aagatttata tatttatgaa gtggatggag aagtagcagg gtttatatgt
     8521 cttaattatg aagagccaga agaatattta ggcttaaatt ggtcatctaa taaaaaagca
     8581 atggtaatac atagaatggc tgtaaatcca aactttagaa agacaggaat agcatctaag
     8641 ttagttgatt ttgctgaaaa attagctgta gaaaacaatg tatcatactt aaagagcgat
     8701 acatattcaa taaactcaaa aatgaattta ttacttacaa agtgtggttt tataaaaatc
     8761 ggagaaatga gttttttagg aaaggagaaa tctttctact gttatgataa aatattataa
     8821 agagcattta taatacaagg ggtaaataat agattttcag cattagtaag ggcataatat
     8881 aacctagtat atgctattat gaaagggatg atttatatga ttggatttct aaagaaaaga
     8941 agaagtatta gaaaatacaa ggatgttgaa gtagaaaaag aaaaattaga taaaatatta
     9001 aaagctgctc ttttagctcc atcatcaaag gggcttagaa catgggaatt tatagtggta
     9061 gatgataaag aaaagctaat taatttatct caatgtagaa ctaaaggtgg tggatttttc
     9121 ttaaaaaatg cacctttagc tattgtaatt attgcagata aagaaaaaaa tgatgtttgg
     9181 atagaggatg caagtatagc tgcttcatac atacaacttc aagctcatga actaggttta
     9241 ggttcttgtt ggatacaagt aagaaataga atgcatgatg ataatataga agctgataag
     9301 tacattagag aagaattaaa agtacctagc aagtacagtg tagaatgtat aatttctata
     9361 ggatatcctg atgaagaaaa gaaagcatac ggtgactctg atttagacta taaaaaggtt
     9421 cattttaaca acttttagta tataatatgt tgtattaaga cattatattt ttttctattg
     9481 ttaatatata cttaaaattg taaaaatata tctgaatttt actaacttat ctaggggtta
     9541 tgtacaagga ttttaaagat aaatatagaa attaatgttt ataatcgata cataacttga
     9601 gtaacaaaat ttaaggaggt taaagtatgg gtatatttaa aacaaaaatg gatgaggact
     9661 ggaaagtaaa ctacattaaa gagtttaatg aaatgagaga ttcttatgag agtaaacttc
     9721 aaaaaaaaca gtttgaggta gatagtttga aatcagaatt ggatagacta agaagctata
     9781 aaaatagcct taagccaaaa gaaaaacaaa ttactgatga tgatataaat aatataaaga
     9841 gtttaagaag agatggctta agctataaag aaatttcaaa tcaaacaagt tggagcaaag
     9901 caactgtaag tagggtatta aatggacttt acgattagca tatacatggg gtgatttaaa
     9961 ttgggatgaa gtatagttac aaaaaatgca taatagattc tattttattg atgtttatag
    10021 ttcaaatatt aaggatgatt ttgaattatg tacttctaag tcaatttgaa tttactcttg
    10081 aaaattttaa tattataaac ttaatttctt ttacattagt tggtttatcg ttaattttat
    10141 ttttaaaaga taattctttg tataacaagg ttagaaatag aaaaatcaca gaagcttttg
    10201 aagaaaataa aaacaatata cttattgaaa agtgtaagct gatacttttt gttgtggttt
    10261 tatctttagc aataattgta acttattgta ctaagggata tgtacttttt aatgtaacta
    10321 tgatgacttt gtctgtattg atagtcccaa tatttgaaga gttatttttt agagaatata
    10381 tatggaacta tctaagtaat tttataaagt caaagagtaa aattatctgt ataacatcta
    10441 tactatctgg aatttataat ataggataca tagatgttat aagaaattat gtaatattgt
    10501 ataacaattc aagctacacc tttgaagtta ttatttcaaa aattatgata ggtactgttt
    10561 ttggtattgt acttggatta gttaagtata ggtttagaga tgtagggttt tgtatattat
    10621 tgaggagctt atttgctata tttattaggt agatagtata atcggtttat aaggttgttt
    10681 taaatttaat tttaa
//
LOCUS       DAEHWO010000115        10655 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEHWO010000115 DAEHWO010000000
VERSION     DAEHWO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10655
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.118"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(618..1352)
                     /locus_tag="KNP54_003614"
     CDS             complement(618..1352)
                     /locus_tag="KNP54_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0894471.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            complement(2363..3001)
                     /locus_tag="KNP54_003615"
     CDS             complement(2363..3001)
                     /locus_tag="KNP54_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBF0894472.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFTLWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            complement(3004..3861)
                     /locus_tag="KNP54_003616"
     CDS             complement(3004..3861)
                     /locus_tag="KNP54_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894473.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            complement(3863..4237)
                     /locus_tag="KNP54_003617"
     CDS             complement(3863..4237)
                     /locus_tag="KNP54_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0894474.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            complement(5399..6589)
                     /locus_tag="KNP54_003618"
     CDS             complement(5399..6589)
                     /locus_tag="KNP54_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBF0894475.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(6605..8560)
                     /locus_tag="KNP54_003619"
     CDS             complement(6605..8560)
                     /locus_tag="KNP54_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBF0894476.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            complement(8577..10643)
                     /locus_tag="KNP54_003620"
     CDS             complement(8577..10643)
                     /locus_tag="KNP54_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBF0894477.1"
                     /translation="MKEVVGSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGEIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYVDKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
BASE COUNT         3604 a         1866 c         1227 g         3958 t
ORIGIN      
        1 tttaaacatt tttcttcact ttgcattatg atatatggtt taaataatct tctttacttt
       61 gtattatgat acatgcttta aatattttta cgcactttat attataatac atgctttaaa
      121 taatcttatt cgctttgtat tataacacat tatttaaata tttttactca ctctgcatta
      181 tagtacatta tttaaatatt tttcttcgct ttgcattatg atacattatt taaatatttt
      241 tactcacctt gtattatggt acattatcta aatatttttc ttcactctgt attatgatat
      301 ataacttaaa tattttacct cactctacaa tattatatat aatttaaata tttttcttca
      361 ctttgtatac taaagtttat ttaaagtatt ttctttccca ttatactatg ctgttaaata
      421 tttttcaact gaagtattgt agaaccttaa aattactata aaaaactata ttctaaaata
      481 cttgtaatac tacgtatcac ccttaacact taagtataat tttaaagcaa aattcttatt
      541 acttatattt aattttgatt ctacatcttt agatataatt ttaagtaatt taagaaatta
      601 ttgtaaatca tatagtacta ctcaataatt aggtttttca atgttccaat tatgtttctt
      661 tgatataatc caccatgact aaaaactatc gtttctatat cataattact tatattttta
      721 atagcatctt ttaactcttg tttgttgctg tgcattacat caacaggctt aagttctcca
      781 ttttctacct gtaacaaatc tccagcaata agtactttag actcttttaa ataaagacat
      841 atgtgacctc tagtgtgacc tcctgtatgt ataacttcta tttcctcacc tagattcaat
      901 ttttcatggt tatctaatga cacatctact ttagtatatg atgatttaaa tccaagtccc
      961 ataacattta gcatactaag catcttatca tcaattttat ctaccatttg ttccaacata
     1021 taaagtttaa aaggagtttc ttctcctgtt atatagctga tttcactttt gtatgcatat
     1081 actttgatat tattcttaga tttttctctt agataattta tgtttcctat atggtctata
     1141 tcatgatgag taattattat attttttaac ttatcaaagc tcgtgttact tttattaaga
     1201 gcatcaatta ttaaatcacc ttgacccgga agacctgtgt caataagtgt tgcatcatct
     1261 tctgtgtaga ttacaggaat atacataact ttatcttcac cgaatacatt tgatgaaatt
     1321 tttaaaacat ctaatccctt tgctaaattc ataatttttc tccttataat tacttaatta
     1381 gaggtcaatt taattaaaga aattgagaaa atgtagattt tcctctagtt atattttatt
     1441 aattaaaaat tattaatacc tagtatatca cttaagttga aggattactc gacttgattt
     1501 ttttgttatt ttatggtata gtaattaata tagaagtaag taattgcaag ctttgcaatt
     1561 acttttattt ttttctaata actattttat ttttgataat tcgtataaaa ttaaaagtaa
     1621 agtaatatgg aaaatatgaa tatagaaaaa ctttaataag aaaataaatt atgaataaat
     1681 aaaagaaacg caatactgta tatagatgat tatttagaaa aataaaatct cttttaataa
     1741 aaataagctt caaaataaac ttttagttca taaagcttag gaggaactaa attgagtgca
     1801 agtgtatcta ctgttcaaaa taaatagttc ataaagcact cttttttata ttaaatcaat
     1861 tatattttcg tcatttcagc aatgaaaaag aaacttatct ctattttgag acagcttctt
     1921 tttattaact tcctactttt tattagtttt ctaaaattga aaagctttat ttataggatt
     1981 ccttagattt atattttgac gatataattt tttaaaaaca tcttaaaaga tggtatacaa
     2041 tacacacaat catactcata attgaaaaat aatcaatgga aaataaaatt actggatatt
     2101 atctattaaa aaatacaaat tgattcacaa gaaacatata atctataata ttatgatgtt
     2161 actctctcgc accaagtaac tttattttca agtaaccttt taaattcata ccatctaact
     2221 tcactcaata aaaatggcaa tataaatatg tactctattt tttactttta aatatctgac
     2281 aagctttata tactattgga agtaaaatac aaagtaaaac agcccaatct ggtaaatgtg
     2341 gcatataaaa gtccccctta ccttatacaa gctccttatt actaaaaatt ttaatagaaa
     2401 taaacattga agctaacagt ataattaaac ttaaaaggaa caatacaata ttcactatca
     2461 tggatggata ctgatatata aatggaattt caaaattgct gtgagctata gttaatggta
     2521 atacaaatga tgaagccatg attatcacca cgaaaaagaa ttttgttgtt tcatatccta
     2581 atttatattg aataggcata taaactccat aaataataga acttattaat aaaacaatca
     2641 aaatatatgt taagtcaaaa gttcctattt gtggaataag taaattttca atccagtaaa
     2701 ctaatgtaca atagataaat accattgcaa ataaaacata cttagattga actaagccac
     2761 gtctaggata aggagttgaa caaagtaata cagatgcttt tgaatattga ctctccttta
     2821 ataatagata ctggcacagc ataaattctg aaaatataat ggatagtaca aatcccaata
     2881 tttgtgcaaa tggaggtaaa cgccacaatg taaataatgg gattcctatt gcaataaaca
     2941 atatcaacaa tacatatttt tttacaatca gaatatcttt tttaactaaa tgaatcaaca
     3001 taattactct ctcctttcaa tatatgcaag cataatatct tcaattgtag gacgctctat
     3061 taaaatatct ggcatatttt tttgcacttc attaattttt gaggtaatcc ctataaaacc
     3121 ataacctgta atttctaaat ttaaaaataa ttttttgatt tcatcattta gaaattgaat
     3181 atcccctttt acttttctat gttcgtccaa tagagtatct ttttcacgct ctaatataat
     3241 acgtccattg tcaatcataa caatcatatc tgctattttg tctaaatcag atgttatatg
     3301 agtggaaaag aaaacaccac gaccacattt tttcatatat cctgttagta tgtcaagtat
     3361 ctgactacgg attagtgggt ctaaaccact tgtaggttca tccataatta aaaactcagc
     3421 tttatgcgat aatgctaatg ctaatgcaaa tttcattttc attccttttg aaagtgtatc
     3481 aatcttttgt tttgggttaa gattaaaacg cttcatattt tgttgataat cttcttcaca
     3541 ccaattatca tatgaaggtg caataatact tttcatttct gccattgaca actcctcata
     3601 gaaatatgaa tcatcaaata caactccaat tcgatttttt aattccttct catttccatc
     3661 gaaatcttta ccaaagattt ttatttttcc actatcacgc tttacgacat ccaatatcga
     3721 acggattgtt gttgtttttc ctgctccatt aacacctata aatccagtta tacaatcttc
     3781 tggtaatgca aagcttatat tagataatga aaaatcggta taagtcttat ttaagttata
     3841 aacttctaaa atattttcca tattaatcct cctgatatag aatatccatc atttcttgta
     3901 actctatctg tgtaattcct agtgcttttg catccttaat catatctgcc attttttgtt
     3961 caactatacg tctctttgag tctcttagta tttctaaatt tccagttgaa ataaatgttc
     4021 ctattccaac ttggcgtgta agaaagcctt cattttcaag ttcttcatac actcgtctaa
     4081 tagtcaaaat actaactttt aaatcattag caaaatttct tatggatggc attgcatccc
     4141 cttctttcag ttcttcagta aatattgctt ctttaatttg ctctttaatt tgttggtata
     4201 atggcttatc tgatgtgtta gaaatgagca ctttcatttt ttatcacccc ctttttatca
     4261 ttttcagtgt gatgttgtta tatacacact atacacttag agcacttttt tgtcaatata
     4321 aaagatgtaa aatattacta tgacaaaata aatatgaatg aaatattaga gattgttgat
     4381 agctataaac actttttaaa accacataag atagaatgta ttaaatattt attaaaagta
     4441 agaattgaat atctaaaaaa aagaggaatc ctgtatgaat gatttgtttg atgataaatt
     4501 aagttataaa ctatttataa aaaacataaa ggaataaatc catttctaat tacaaacata
     4561 ctaaaaaatt tagatagtaa taaatagata gtaataaata gatagtaata aatgggatga
     4621 atttataaga atttggatag aggaaagagt tattcaagag tgtagactag aggtaaactc
     4681 tatattaaaa aaatttaaat ttggatatta tgatgcatgg aatatttgca gaagtaacct
     4741 tgctataagt atagaagatt tttttgatta caaaagataa tactctaaaa tgtgaggatt
     4801 tcaacattca atactgtact ttaaataata tcactgcaaa ataccatcca ccttttacca
     4861 taattgaata ccctaattat tttaaaaaag aaaacattag aaacagaaaa ccttggatat
     4921 ataaaataaa aaatactaac ttctaaaaca cggatactct ttgataaata aaacaaaaaa
     4981 taattttaat aattaaaatt ggctatctca aactagagat aagtctcttt ctcactttta
     5041 aaacgttgaa aatatattcg atttcgtaca aaaaagagtg ccttagaact aaaaagttca
     5101 ctttgtggca ctcccttttt tctcctcttt ttaatttttt ataaaaattc ttcaaaaata
     5161 ttattaaata ccctatatta tacataaatc aaattaaagt tgcattttag caaataaaaa
     5221 caaattataa ctattagcat agcaaataaa aaatctgctc tcttataaaa tcaaattata
     5281 attataaaaa gaaaatattc ttataacaaa ttagctaata taaaattatt ttataaatta
     5341 atactacttt ttagcttctc ctataaatta ataccacttt tttaactttg aaacctatct
     5401 acaacattgg taccataaga ccagctacca caatagaaat catacaagcc ataccaccaa
     5461 ctaccagctt aggcataatc ttagacatca aatatgctct ttcttcttcc gtttctccaa
     5521 cagcattaca cacttcattt gaaattaaat atgtagttgg gaatcccaac atctgacaaa
     5581 accctactcc aaaagcaaga ggtttagaac cgataatttt ccaacctggt aacaccttca
     5641 tcataaggaa tataccaatg atagaagctg caaacatacc cacaattggt acaaaaagac
     5701 taattaaatc tgtcaaagaa acttttgcta aagaaggaat aacagctgca aacacaacca
     5761 tgttgataaa tcccttgatt tttccttttt ccaaaatgtc ttttggcaca ataccaatac
     5821 gtgttacaat aacaccaaca acaagacata caatagaata atttacatga ataatctctg
     5881 aaagttcata ccctagataa gagaataatg ctataaaaaa tatacaaaca tttgtagaat
     5941 aatatttatc gtatttttca cagaaagctt gttttacttt tgtgcctgta ttctctgctt
     6001 ctttcttatc agtatcaaca tttgctaaat caatgccttt tgattttgct tcatgatatt
     6061 ctactaaaag acggtttgcc tcttgtaacg ctgctcttga agctattggt gtaccaataa
     6121 acttctgaat tgcaaataca actgttgctg tagctgctgc aagtgtcagt cctttttcta
     6181 gtgctgcttg tgtcataata gtagtagcag gtaaagctcc atttataact ggtatgcttg
     6241 tcaatactgt tgattttcca aacaaaggaa tacataatga gacacagact ataactgcta
     6301 caattccaag ccatgctgtc aatactgttc tccattcgtc tataaattgt ttaacattca
     6361 acattgttcc catactaaac ataatcattg gaacactcca actagctgct gcggtcatac
     6421 ctgctttttc aataatatca gctggtattg cttttgtgac aaatagaatc aaaaataaaa
     6481 gtagtgtaac aaatacagct gatacttttg cttttgtttt gcttgcaatt aaatccccaa
     6541 tagcaaataa aactaatacg acactaaacc ataataacat atcactcata gaataacccc
     6601 cttattataa atatctttca aaccaatcta caatagcatt tgctcttgca attctattag
     6661 atggtcttcc atttctagac aatccatgtg tatctccgtg gaacaaatac atttctgtat
     6721 ctacaccaag ctgttttaat gctgtaaaca tttggaaagt atcccccata aaacatctat
     6781 aatccctatc actatgtaag aacaatgttg gtgtcttaac atttttcaca tatttaatag
     6841 gtgaatgatt ccaaagaacc tcctcatgat tccaaggcgt cttatctcca caagtctgct
     6901 tcataattct atccccaaag tcaataatta aagaagctgt aatcaagtta ctaatacctc
     6961 tttgagaaac tgctgctttg aaacggtctg tatgaccaat tatccagttt gtcatataac
     7021 caccgtaact tccccctgca acccctaagc ggtctgcatc aatcccagga tatttttcaa
     7081 tacaagtatc tacaaattcc ataagatgct catagtcaac atacccccat ctttctacca
     7141 tttctaagaa tttttcacca taaccgtcac caccatgagg gttacaataa atcacataca
     7201 ttccctttga tgttacacac tgcttcaagt gtgtaaacat atagccatat gcccatttag
     7261 gcccaccatg aatgaacaat acagcaggat atttttcgcc ttctttagca tctataggtg
     7321 gtataacaaa accatcaact tcttctttat tttttgctac aaacgtcaat ttttcaggta
     7381 atgaaacctt atgagtatct aaatatggtt tagaaaaagc agtcattttt ttcattgtac
     7441 ctgtagtcat atcaatgcta tatatttctg ctaactcata atctttcaac attactgtgt
     7501 acatggtgtt gtcgtaaata tcaaaagatg taaaagcatc tacttttgtg atgatacgta
     7561 tattacctgt ctttgtatca aactcattaa attctgtcat agttctgcaa attcttgcac
     7621 caataaattt atctcctata actttattac tacgtccacc accatatact gcatctacat
     7681 ccagtaatgt agcatacata ccatctggac tagcaatcat atttatttca ctagtactca
     7741 aatcaagtat aaaaatatca tgattctgtg taatagaacg gtctaatgtt gaagcttgca
     7801 acattacttt atctttgcca atatattttg ccaaacttat ttggtacttt ccttgtggta
     7861 caagttcttt ggtttcacca ctgtctatat gatactccca aagtccagaa aaaggagttg
     7921 cacaatcttc ataaatctga ccagtatata aaattctgtt tttatccgaa gaaacatcta
     7981 tacctgctac ttcacaaaat tttggtgtaa tggcttttgt tatattttca ccttcttgat
     8041 ataattctaa tgttacacgt cttctttgag aaaaattttc tccatctctt ataaaaggtt
     8101 tatctgtaaa tgtccaataa tctacaccct ctactgccct atctggttct gattttttag
     8161 aatccgttgg attttttgtt gtcagtaacc acaatttatt tccaagtgat acaggtacgc
     8221 tacaagcttt tggaatagaa aatgcttttt ttgcttctcc tccttctata gaaatagtgt
     8281 aaaaatctgt tgtacctgct tttggcttat ttcttttaga tgtaaaaagt agttctgtat
     8341 tagaaatcca actaaatgat gttacatctt ttgtttgagt catatgtatt tgtttttctg
     8401 ttttgatgtc catcacatat aagtcatgtt catagcagtc tttttcctcg ttgatatttg
     8461 atataatata agcaatatgc tttccatcag gtgaacaaga aatatcatga gggaatatat
     8521 attcaaaaat atctgaactt tcaatcttta ttttttccat ttttatattc tcctttctac
     8581 tgtcctatgt tatctttttt tatatatacc gaaaaccaat ctagcatttc aactaatctt
     8641 tgtagctttt gttttggtct accagaacga gacagttcat ggttttctcc ttcaaataga
     8701 caaagttttg taggacaccc atgaattttc aatgctgaaa acatctggaa tgcttcttgc
     8761 atatagcatc tatagtcttt ttcaccatgt aaaaataaag tcggtgtaac acatttatca
     8821 acataagcaa gaggtgactg tttccattga agctcgtggt tttccatatg agaagcacct
     8881 gtttgtcctt tgcagaaata ataaccaatg tctgttgtac cctccatgcc actccagttt
     8941 gcaatagaac gctgagcaca agcaacagca aaacggtttg tatgaccaat tatccaattc
     9001 gtcataaatc caccataact tccaccttca acagccaatt ttgttttatc aatgtctgta
     9061 tatttttcaa gtacagtatc tgtaaattcc ataaaatcta tataatcaat ttctccaaac
     9121 tgtttcctaa tatctgcaaa agcattgcca cgaccttcag acccccttgg gttacagaag
     9181 aatacaaagt aacctgcact tgtaaatacc tgtatctcat gcataaaata tggtccatat
     9241 gtcaatcttg gtcctccatg aatcgccaat acagctggat attttttccc cacctcataa
     9301 tctactggtt tatatacgta tccttgtatt tcccatttag aacttccttt tgactctatg
     9361 tattctggca cagaaatttt atattcctct aaaatatggt catttaaatg tgttttctta
     9421 cacaatgttc cattctctac tgtataaact tctggtaatc catttcctaa acaacccaca
     9481 catacaatat tgccatcttt tacatctata aaatcaactg aacctgtctg tgttactttt
     9541 tcctgttttc ctgttggaat atgtattctt tcaataatgc agtccatatc tactgtagaa
     9601 gtgtaataaa tatattctcc atctaccttt gttgtctgac cagcacccat tttaacatca
     9661 gatgttactg tatttccaat acaatgatgt tgatgccctg aaagaagttt catttctttc
     9721 gtatcaatat caatagtata aaaatctcca ttttctccat ttccataaga taaagcatca
     9781 gttaggttta gtatcacttg attttgatat aattcaaaac cttttataat atacttatct
     9841 ttttctaata tacagacatt tgtgtttgtg tttgtatcaa atacatagac cccatttttc
     9901 aaacctttta catctttaaa ttcttgccct atatataaga tttttccatc acttattttc
     9961 atacctacaa cattaaacat aggtgctgta attgccttca actcatttat attactatcg
    10021 tatacatata ggcgttttct ttttctgcta atatatccct ccccattgac agcataagga
    10081 atttctttga aatgttcata atgtcttttg ttataagcat ttattttttt ctgttgttct
    10141 tcttctggca atccctctac aataggtcgg tcattgtcat aagaatcaat aactgcatac
    10201 aaaccttttc ctataggatt caatttacca cctttgatag ggagtctaaa aagttcttct
    10261 gcttctccac catttaaaga taaagcatag taactcatgc attgcttacc gtttttgaca
    10321 gcttctttta ctttttcatt tcgcaaagca gggaacaaga tagtattttc atcttcccag
    10381 gcatatgctc caacagagtt tatagacgtt atttgtttta attcgccagt tttattgttt
    10441 aatatataaa cttggcttgt gtaaccattc tctttgatat cagctttttt tacaataaat
    10501 gctgtatatc ctccatctgg tgatatttgg caatcactta taaattgata ttccaaaaat
    10561 gtttcactcg taaatagctt tttcatagta ttttctatcc tttctttagt aatttttttc
    10621 aaactcccta ccacctcttt cattttttat tttaa
//
LOCUS       DAEHWO010000116        10548 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEHWO010000116 DAEHWO010000000
VERSION     DAEHWO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10548
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.119"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            534..1964
                     /locus_tag="KNP54_003621"
     CDS             534..1964
                     /locus_tag="KNP54_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0894478.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            2067..3170
                     /locus_tag="KNP54_003622"
     CDS             2067..3170
                     /locus_tag="KNP54_003622"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBF0894479.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENRKFVAVLKEILNIKGEPSIG"
     gene            3185..3421
                     /locus_tag="KNP54_003623"
     CDS             3185..3421
                     /locus_tag="KNP54_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0894480.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            3438..4487
                     /gene="vorB"
                     /locus_tag="KNP54_003624"
     CDS             3438..4487
                     /gene="vorB"
                     /locus_tag="KNP54_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBF0894481.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4489..5229
                     /locus_tag="KNP54_003625"
     CDS             4489..5229
                     /locus_tag="KNP54_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBF0894482.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            5232..5771
                     /locus_tag="KNP54_003626"
     CDS             5232..5771
                     /locus_tag="KNP54_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBF0894483.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            5895..7994
                     /locus_tag="KNP54_003627"
     CDS             5895..7994
                     /locus_tag="KNP54_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBF0894484.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMEKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8261..8776)
                     /locus_tag="KNP54_003628"
     CDS             complement(8261..8776)
                     /locus_tag="KNP54_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBF0894485.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(8868..10079)
                     /locus_tag="KNP54_003629"
     CDS             complement(8868..10079)
                     /locus_tag="KNP54_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBF0894486.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKFLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
BASE COUNT         4010 a         1267 c         1902 g         3369 t
ORIGIN      
        1 gatattagat ggaaattacg taaaaataga aaattgaaaa ttctgaaatt tttgcatatt
       61 gatatttatc tcatagattc ttttttgtaa ttgtaacacg cttttatttt taaatcaata
      121 gtacatgtat aaaaataaaa ggaatttaaa taagaaaaag atatttttaa tatctggatg
      181 tagtatagaa atatcttgaa taaattattc ttgaataaaa ttataaaaaa ttaaaatcac
      241 tagaaatatg ataaaataat ttaaaatacg catttcaatg acatttcaaa acaagaaaat
      301 aataaaaaac aaacctaaat taagtctaaa tagcttttta gttaatttta gtagtaaaaa
      361 ataaaactta aaaagtgttt gacaattatg aattttgaga atataattaa attaaaatta
      421 tacacatata aaaatatact cctgaatcaa gaatgagata tttaagattc aaaatatata
      481 ttattatacg tgaataataa aaagtaagta aattttataa gggaggggta gatgtgagta
      541 gtcaagaaag caaaccaaaa ggaaatctta tatcaaattt tagagatgat atgagagacc
      601 ctaagaaaag agcaatatac acatattcaa gttctataaa tttagcgtac aattttatag
      661 gttactttgt atcaactgtt acaaatattt ttttaactga tgtggcaaaa cttggtgtaa
      721 ttatggcagg tggtatgcaa attatacaat ctttcataaa aattgctgta gctcctataa
      781 caggtacagt atttgacaaa caaccattca aaaaaggaaa gtattatcca tggcttagat
      841 atgcaccagc agcgttagca ttaacatatg gaatattttt catagttcca ttaatgaaaa
      901 taagtccagc attactttta cctttgatga cagctttatt attaatagca tcttgtgctc
      961 agcaagtagt tttcactata atttatgcta tttaccctgt agttgctaag acacctagag
     1021 accgagttat aggctcaact actacgaata tatttaaaga agttggtaaa ttcttagtag
     1081 gtttttcata tccgttatta ttagttttat ttgcagatgt attaggtgga gaaggaatgg
     1141 gttatttagg tacctactta ttctttgcag caggatgcct tttagtattt tggttttctt
     1201 caacagagat aataaaatct ggagcagaag aagaagttct tcaaaaagaa gagaagccaa
     1261 agattaaagc aagtgaaatg gcaaaagctt tattcactaa tgtaccactt atgatggcat
     1321 tttgtttaga atttcttata tgtataagat ctataggatt aggacctttg gctccatatt
     1381 attttaaata tgtaatagaa gatgaacgtg gattagcagt atttttatca atcatgcctt
     1441 tggtaagtgt agcattcatg tttttcgcac cagtgtttat aaaaatctgt agagagcaaa
     1501 aactagcttc aataatttct ttttctatat gtgcactatg ccacttattg gttgcatgga
     1561 ctccttgggg gaaaactact ttaggagtaa ctatgttgtt ggcaattggt ggaggttttt
     1621 caaatgtagt atcaataata aatcttaatt tctttgccgg ttcttgtgat tatgggcatt
     1681 ggaaatcagg aaaagactta cctggcttaa gtatgtcact atatccagtt gcaatacaag
     1741 taggagtatt acttgcaact actataagaa cagttttaat gaactcaatg ggatatcaag
     1801 ctgatatggt agtcacagaa gcagttaaat caggttttat aaatatgatt tcttattcta
     1861 tggcaatacc tttaataata gctgttgtta tagcaatact atatccagta agtgacaaga
     1921 aattaaacca aataagagaa gagttaaatc aaagaaatgc ttagttaaaa gaaagttgag
     1981 tagatggtta atttaagcta ttaaagtaag tagacgcaat agcgtttata taaatgaaaa
     2041 tacatataca gagggggctt ttaaaaatga tagaaaaatt attgagaaat accgtaaaag
     2101 aattacatca atatgttcca ggtgaaccaa tagaaaaagt taaggaaaaa tatggtgtaa
     2161 aagaaataat aaaattagct tcaaatgaaa atcctctagg accatcacca aaagcaatag
     2221 aagctatgat tgaaatgtta aaacaaggtc aactttatcc agagccagaa gctaacgaac
     2281 ttagaagaaa attagctgaa aagctagatt taaaaccaga aaattttatt gttgctaatg
     2341 gtgcagataa cgttatcact ctaataggtg aggcttttat aaatagagga gatgaagtta
     2401 tatattgtaa cccaacattt ccatcatata gaactgcaac tataaaaaat gaagggatac
     2461 cagtagaagt acctttaaca gaagattata agtatgattt acaaggtata ttagataaga
     2521 ttacagataa aacaaaatta atatgtgtat gtaaccctaa taatccaaca ggaacaattg
     2581 tggatgataa agagttagaa gaatttttaa agaaagtccc tgaaaatatt ataactatat
     2641 tggatgaagc atatatagaa tttttaacag ttcctaatta tgtggatgga cttaagtatg
     2701 taagggaaaa ttataacgtt atagtaacaa gaactttctc taaaatatat ggtcttgcag
     2761 ggcttagagt aggatatggt attgctaaag atgagataat aagaacttta tttacagtaa
     2821 aagagccttt ctctgcaaat cgtgttgcta taagtggagc aacagcagca cttgatgatg
     2881 aagagtttat aaaagaaaca tatgaattaa atagagttgg aatggcttac tttaaagaag
     2941 agtttacaaa aatgggattt gatgttgtag attcacaatc aaatttcctt tatgtagata
     3001 tgaaaacaga tatacctaag ttatttgaag acttgaaaaa aagagggttt gtaataagac
     3061 caagtgctac acatgcacgt gtaagtattg gaactatgga agaaaatagg aaatttgtag
     3121 cagttttaaa ggaaatatta aatattaaag gagagccaag tattggataa tagatagaaa
     3181 tattatgaaa cggggtgtag atatgaactt aaaaataaac gcagagagat gtaaaagttg
     3241 tgaatactgc gttatatctt gtaaaaaagg agcattaaaa atatcaagta agataaataa
     3301 agaaggttat gctcatgtag aagttgatga gagtaaatgc atactttgtg gaatttgcta
     3361 tcaggtgtgt ccagataatg tttttgaaat aattaaagaa gaagcatgtc aagaggctta
     3421 gaaggagttg ggataatatg aaaaagatgt ggaaggggaa ccacgccatt gcagaagcag
     3481 ccctaagagg aggttgtgaa ttttatgcag gatatccaat tacaccacaa acagaggtaa
     3541 tggaattttt atcacataga atgtctgaac ttggaagaac ttttatacag tccgaaaatg
     3601 agatggctgc tatatatatg gtatatggag catatgcaag tggaatgagg tctatgacga
     3661 gttcttcagg accaggaata tctttaaaac aagaagggat ttcttactta tgtgcaaatc
     3721 attacccttg tgtaatcgta aatgtacaga gatgggggcc tggtcttggc tcattggact
     3781 cagcacagac agactatcta agagatacta gagggggagg aaatggagat tatcatttga
     3841 tagtttatgc accaaacagt attcaagaga ctgtagattt gatgtataac tcatttgatg
     3901 tagcggagaa gtacagagtg cctgtcgaaa ttttgacaga agcagcttta ggtcaaatga
     3961 tggaaccagt agaatttcca gagtttaaga agagagaagg agatttaggt tggacttatg
     4021 atggaagtaa tagagaccat gcaaaggttg cagataacca aaagccaact ttttgtatgg
     4081 agaaacgtat gagaataact gaaaatgaac aacaatggga agattatcaa gtagaagatg
     4141 cagaatatgt gtttgtagcg tttggtatac catcaagaac aactatgaat gctgttagaa
     4201 gacttagaga acaaggtgaa aaagttggaa taataagacc aataacagta tggcctttcc
     4261 catataaagc atttgaaaag gtaagtaaag atgtaaaagg atttatctca gtagaatcaa
     4321 cagacacagg tcaattagta gaagatgttg ctttagcctc aaagaaagta tgtaaagaaa
     4381 atgtacctgt gtatggttta tttagtggaa atcatatacc aaaaacattg caagtaatgg
     4441 acacttatag caaaataaaa tctggcgaaa tcaaggaggt gttctaatat ggctacagaa
     4501 aaattaacac ctagcgttgt ttcaatacca aacaagtttt gcccaggttg tggtcatgga
     4561 atagtaaatc gtataatagc agaggtaata gaagaacatg gatatgaaaa aaatcatgta
     4621 ttaacattag gagttggttg tgtctgcaat atgaatttta gctggaatgg tgataagatg
     4681 caaactgcac atggtagagc ttcatctaca gctataggag ttaaagtagc acttccagat
     4741 acattagtaa tgacttacca aggtgatgga gatgcttatg ttataggtct ttctgaaact
     4801 ttaaatacag catatagaaa tcataatgtg actgtatttg taataaacaa taataatttt
     4861 gcaatgactg gtggacaaat gtcatggacc actatgccgg gtcaagtcac aacaacaagt
     4921 gtaaatggaa gagatataaa gactactggt agtccactga aagttcctga gatggtggca
     4981 aacttctttg atgtagcata tgtagcaaga ggttcagttc atagcccaaa ggaaataatt
     5041 aatctaaaaa aatatataaa aaatgcaata gaagctcaat taaatggaga gggatattcc
     5101 ttagttgaaa tattagcacc ttgcccaact aactggggtg tatcactaga gaaatctatc
     5161 aaatggatgg aagaagaaat agtgccatat tatgctcttg gcgaatttaa gcaaagggat
     5221 ggtgaatagt tatggaaaaa gagctagtat ttgcagggtt tggtggtcaa ggagttttaa
     5281 ctcttggtct gattgtagct gagtcagcac ttgaattggg gaaacaagta acttggatgc
     5341 ctgcatatgg tccaactatg agaggtggaa aagcctatag tgtagtaaag ttttctgatg
     5401 agagtatagg tgggcctgat atggaagaaa tagatgtttt agtagcaatg aataaaccat
     5461 ctttagatta tataaattta gttaaagaag gtggaacagt agttattaat acatctgcaa
     5521 tagatgagaa tgtaacatta agagaagata taagtgtagt taaaataaat tgtcaggaat
     5581 tagctcaaaa agtaaacaat ccaaaagcag caaatatagt agtacttgga gcattaattg
     5641 ctaaaactgg gttatttgaa aaagaattag ctttaaaaac tatgtgtgat ttctttgagg
     5701 aaaaaggaaa aggaaagttt aatgttcaaa atgaagcagc attcatggaa ggctataata
     5761 acgccatttg ataaattacc cttatcttaa gtgatttatc tcaagattta ataatcttta
     5821 gtgccaagag aaacttcatc ttgagataaa attcacttaa aatcacaact ataaacatat
     5881 aggagcgtga atttatgagt ttggaaaaac ttattagacc aaaaagtatt gctatagtag
     5941 gagtgactga taaacttggt tttggaagaa gtgcagcact tagtatagta aaaagtaagg
     6001 aaacagatag agtatattat gttaatccca aaagagaaga attgtttggg agaaaatgtt
     6061 ataagacgat acaagaagtt ccagaagtag tagactgtgt agtagtatgt acgcctagaa
     6121 atgtagttcc atctgtatta aaagattctg gagagttagg aacaaaggca gcagtggtat
     6181 atgctagtgg atttgcagag gaaggtacag aggaaggtac agatttagaa aatcaactta
     6241 tagaaatatc aaatacatac gatatgaaaa tattgggtcc aaactgcatg gggttgctaa
     6301 attgtataga taaggttaat ctatgggcag gaggttctaa atgggattta gatactaaaa
     6361 aacctggtat aggaattgta ggtcaaagtg gatttataac tgctgaaatt gtttcaagtg
     6421 attattttaa tatatcttat ggtttttcaa caggaaatgg aaatatagtt acactagaag
     6481 atgcagtaga tttccttgta gatgatgatt atgcatcagt aatagcaatt taccttgaag
     6541 gtttaaaaaa tcctcaaaaa tttatagatg ctttaaaaag ggcagcacaa aaaagaaagc
     6601 cagtaataat attgaaatca ggaaggtcag aaaaaggtgc tatttctgct gcttctcata
     6661 caggaaattt agctggttcg agtaaagctt ttgaaagtat ttttgaaaaa tatggagtaa
     6721 tttctgtgga aaatttagaa cagtttatgt gtttagcaca agcttttagt gttttagatg
     6781 gtaatttacc tgcaaattct aattttgcag caataaactt ctcaggagga gaaaatacta
     6841 tttgtgcaga tttagcagaa gaaaatggtg tagaacttgc agaaatatct tctgaaacta
     6901 aagaagaaat ggaaaaatat cttccaggat ttgcaacacc taaaaatcca ctagatgcta
     6961 caacagcatt attccatgaa aaggatatga tagtaggttt attacatacc tttgaaaagg
     7021 atgatagtgt tggatttact atggtaggtg caaatataag agatgaagaa aatgaaatgc
     7081 atgaaaccct ttgtaaagct gtaagtgaag ctagagaaca aggattgaaa aaacctgtgt
     7141 ttgcagttcc tacacttgaa ggaaatagat atttagatta taggactaga ttagaagata
     7201 atcaagtgcc tataatgtca tcagttggaa ctacatttac ttgttttaat aaaatggcta
     7261 agtttataga ttatgattat tcaaaaagaa ctttagaatt taaagctgtt aagaaaagag
     7321 agtcaaataa tgtagtagca ttatcagaat tagatagtaa gattgagatg aaaaaatatg
     7381 gagtaccagt tccaggacaa ggtaatgcaa aaagtattga tgaattagat gaaatcttaa
     7441 aatatattaa gtatcctgtt gttttaaaaa taaattcttc tgaaatattg cacaaatctg
     7501 atgttggagg agttaaaata ggaattaaga atagagatga ggcagtagat gcatataatg
     7561 agattttaac taatgtaaaa aaagcaaaac cagatgctaa tattgatggt atattagttc
     7621 aagaaatggt agaaagtggt atagaaatta ttattggtat aactaatgat gaccaatttg
     7681 gaccaatgtt attagtcggt ttaggaggag tatttgtaga ggtatttaaa gatactacat
     7741 tatatccatt acctataaat catgatgaag ctattatgat gcttaaaaaa ctaaaatcat
     7801 ttaagctttt aaatggctat agaggaagtg agccatgtga tattgatgct cttgcagata
     7861 tgatggtcaa gttaggaaaa tatgcttatg aaaataagga tgaagtcaag gaaatagact
     7921 taaatccagt gtttgtatat cctaaaggaa aaggcgtatg tgcagtagat gccttaatag
     7981 ttaaatataa atagtttata agttttggta ttcaaccata attaaagcac caactgaaaa
     8041 tcacattttg taagttagat agtgtgattt tcagtcaccc caaatttaat ttaaaaatat
     8101 tttaaaatga aagtatagtt ttaagtttca ttgtgaaata gcactgtata aacaataaaa
     8161 tactacgtat aaaacgaata ataaaaggtg ttttaatgat aagaatcaat cttgattttc
     8221 attaaaacac cttctttatt atattaaaaa tttttaaacg ttatattgtc acaggtgggt
     8281 ttgttggagc tgcatatgta cgattagcaa attcttggtc aacaaagaat agcccaccct
     8341 ctccagcaag tttaacacgt tttatattgt cttcacaatt tgtttcttct tctgcttgtt
     8401 cagatataaa ccaaagtaag aattgagaag ttctaaagtc tgattcagag tttgctacag
     8461 ctgctaagtt gtttattaaa gctgtaacct ttttttcatg agctaacgta cgctcaagaa
     8521 tatccattgc agaagtaaag tctgaatctg gcattgggat agcatcaagc tgaacctttc
     8581 ctcctacatt atgtaagtat ttgtaaaaaa acatagcgtg gtctgtctct tctttatatt
     8641 gaacataaaa ccaattagaa aatcctttaa gtccttctgc ttcaaggtaa gaagacatag
     8701 aaagataaag atacgcagaa tataattcat ggttaatctg ctcattaagt aatttttcca
     8761 ttttagctga aatcattttt atacctccaa attttaaatg ctcttataaa atataataat
     8821 attaaatgga aaaatattca ataaaagtgt ttaaatattt tacatattta ataaaaattt
     8881 atactaccat taaaaaaatt ataacttaca atggctatag agccaattaa tggtgcattt
     8941 gctccaaaat ttgaatgcct tacacttatt tttttatatt tagaaaaact tgctgaagca
     9001 gtcaattttt ttaataatgt attttctata aatgtaccag gtatattaaa gtcatagcct
     9061 attattatag aactacaatc aatcaatgta agtgtattaa ctaatgcata tgatacgtat
     9121 gtacaaaatt catcaagcaa aaacatggca agactatctt tattatttgc ctcatctatt
     9181 aacttgacta aagaaaaatc tttacagtta attaatgggg agttaggata aatatggctc
     9241 aatgattcaa ttcttttaat tagattactg acacttgtat aataatctaa acatccattg
     9301 ttaccacaac tgcacaatgg tccactaaaa ttaattgatg tatgtcctat ttctccactt
     9361 tgtcctaggt tgccagtatg aagtttattt tctagaacta gaccagctcc aataccattc
     9421 attatgtgta ggtatatata atttgatata tttttaccta aaccatacat tttttctgct
     9481 aatgcacccg aattagcatc atttatcaaa aatattggca aatcagacat ttcttttata
     9541 aaatctacta tatttaggtt tgatacattt ccaaaatctg ggggatttag tatggtacca
     9601 tttatatcat ctactggacc tattgaagaa ataccaattc caattatatc tctcttgttg
     9661 attttcatta ttttagtaaa cattcttttt attatatctt ttaaaacatc atttgataga
     9721 aatttagggt aagtttcaga aagttgtttt acaatattac cttttaaatc tgaaataatt
     9781 accttacata tatttcttct tattaggatt ccacaaatac aaggcgatat attagaaata
     9841 tctaataaaa taggtttacg acctgatgaa tgtgcattta aagttgatga ctctatttcc
     9901 ctaatcatat tttcattaat aagttcagta actagatttg ataaagtcat tttagtaagt
     9961 cctgtagact tagctaaatc aactctggac ataggtgtat ttgtagaaag taatttcaat
    10021 attattaact tatttttaat ttttacatct ttgatgttag aaccttgttt gttactcatc
    10081 ataaatctcc ttaaataaag ttaagtgttt tatttatttt caagtatact atcaccttat
    10141 aatagagtaa cattttttta cttgaaaata tcattaatta gaatatatca cattatatat
    10201 cataaaacat ataaaaaaat attagaatta aattaaaagt gaaaagtaga ttgatatata
    10261 aatagtaaat acttaattaa aaaaagataa tgatagcaat aattattgtt accaagaatc
    10321 tactacttca agtgttacct taggtattta agttgatagt ggtttgcacg taataaactt
    10381 gatgtaatat atattcttaa taatatcgat aaaagattta cttaaaaata atatagatta
    10441 tgtaaacata taatctattt attgtataca ataaaatttc attttgtaaa acagtgaatt
    10501 aaatatgtaa tatagatatc gatttttatt acaaattgtt actaaata
//
LOCUS       DAEHWO010000117        10400 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEHWO010000117 DAEHWO010000000
VERSION     DAEHWO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.120"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            132..2633
                     /locus_tag="KNP54_003630"
     CDS             132..2633
                     /locus_tag="KNP54_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBF0894487.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVKNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            2793..3461
                     /locus_tag="KNP54_003631"
     CDS             2793..3461
                     /locus_tag="KNP54_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894488.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            3445..4722
                     /locus_tag="KNP54_003632"
     CDS             3445..4722
                     /locus_tag="KNP54_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBF0894489.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            5123..5344
                     /locus_tag="KNP54_003633"
     CDS             5123..5344
                     /locus_tag="KNP54_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894490.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(5633..6397)
                     /locus_tag="KNP54_003634"
     CDS             complement(5633..6397)
                     /locus_tag="KNP54_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBF0894491.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            6671..7345
                     /gene="fsa"
                     /locus_tag="KNP54_003635"
     CDS             6671..7345
                     /gene="fsa"
                     /locus_tag="KNP54_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBF0894492.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVGKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(7467..8861)
                     /locus_tag="KNP54_003636"
     CDS             complement(7467..8861)
                     /locus_tag="KNP54_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBF0894493.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(8939..10285)
                     /locus_tag="KNP54_003637"
     CDS             complement(8939..10285)
                     /locus_tag="KNP54_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0894494.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
BASE COUNT         4227 a         1234 c         1611 g         3328 t
ORIGIN      
        1 ttgatttaat atacctatag ggggtataat aaaaatatag atttctaaat aagtaattta
       61 tcaatattac atatcaaaat aaaacgttac aaattagctg aaaatatatt gaaagaaagg
      121 aagattttat tatgagttca aataaagtgg tagaaagtta taaaattaca ggtatgacat
      181 gtgcagcttg tgcaaaggca gtagagagag taactaagaa gatggatgga gtatatgacc
      241 aaagtgtaaa tatagctact gaaaaactta aaatagaata tgataattct aaggttaatt
      301 ttgatgatat aaagcaggtt gtagaaaaag caggatatgg aattataaag gaagaaagta
      361 ataaaaaaat tgatatgaaa attgatggaa tgacatgtgc agcttgtgca aaagctgtag
      421 agagagtggt aaaaaaattg gatggagtag aaagtattag tgtgaatatt gcaacagata
      481 aagctaatat agactatgac ccatcaaaag taaaattatc tcaaataaaa gcagctattg
      541 aaaaagctgg atataaacca atagaagagg taaaaaataa ggttgatgtg gatgaagata
      601 aattgagaaa agaaagagaa atgaagtctt tatttgttaa atttatagtt gcaatagtat
      661 ttgcagtacc tctgttttat atagcaatgg gacctatgat aataaagcct atagggccat
      721 ggcctttgcc agaaattata aatcctatga caaatacttt taattatgca ttaattcagt
      781 taattttagt aataccagta atgatagctg gttataaatt ttatataaat gggtttaaat
      841 cacttttttc tttaagccct aatatggatt ctttagttgc aataggaaca ttagccgcat
      901 ttttatatag tctatatacg acactacaaa tagccaatgg acaaattcaa ggtatgcacc
      961 atcatcagtt gtattatgaa agtgcaggaa taataatagc acttatctta cttggtaaat
     1021 atttagaatc aaaatcaaaa ggaaaaacat cagaagcaat taaaaagctt atggggctac
     1081 aacctaaaac tgcaatagtg ttagttgatg gtaaagaagt tgaaactcct atagaagaag
     1141 tagagatagg agatatacta ttagtaaaac caggaactaa aatacctgtg gatggagttg
     1201 taatagaagg atatacatca gttgatgaat caatgcttac aggtgaaagt ataccagtag
     1261 aaaagaatgt tggaagtaag gtgacaggag ctagtattaa taaaaatggt gttattaagt
     1321 ttaaggctga aaaaattggt ggagatactg ctcttgccca aataataaag ttagttgaag
     1381 atgcacaagg tacaaaagca cctattgcta aacttgccga tactgtatct ggatattttg
     1441 taccaatagt aattgcaata gctgtagttg catcattatt gtggttttta ataggaggaa
     1501 aagatatagt atttgtactt actatattta tatcagtact tgtaattgct tgtccttgtg
     1561 cattaggatt agcaacacca actgctataa tggttgggac tggaaagggc gcagaaaatg
     1621 gaatcttgat aaaaggtgga gaggcattag aatctgcaca taaagtaaat acagtgatat
     1681 ttgataaaac aggtactata acagaaggaa agccaaaagt aacagatata gtattaaata
     1741 ataatgtaaa agaagaatat cttatcaaga ttgcttcaag tgcagaaaaa ggttcagaac
     1801 atcctcttgg agaagcaata gttaagtatg gagaagagaa gaatataaaa tttgaaaaag
     1861 ttgataattt taaagccata ccaggtgctg gtatacaagt tactattaat gatgaaagta
     1921 tattacttgg aaatagaaag cttatgaatg acaataatat aaagcttggg gatttagaag
     1981 aaaaatcaaa tatattggca agccaaggta aaacacctat gtatatagct gtagatggaa
     2041 atttatcagg tataatagca gttgcagatg tagtcaaaga aagtagtaaa aaagcaatag
     2101 aaatacttca tgatatggga ataaaagttg caatggtaac tggagataat gcgaaaactg
     2161 caaatgctat agcaaatcaa gtcggtatag atatggtttt ggcagaggtt ttaccagaag
     2221 ataagtcaaa agaagttgaa aaactacaaa atcaaggaaa gtttgttgca atggtagggg
     2281 atggaataaa tgatgcccca gctcttgcaa aagcagatat agggatagca ataggaagtg
     2341 gaacggatgt agccattgaa tctgcggata tagtacttat gaagagtgat ttaattgatg
     2401 ttccaacagc aattaaactt agtcatgaaa ctataaaaaa tataaaacaa aacctatttt
     2461 gggcatttgg atataataca attggtatac ctgtagcagc aggaatatta tatgtatttg
     2521 gaggaccttt attaaaccca atgattgcag cagcagcaat gagcttaagt tcagtttcag
     2581 tcgtatcaaa tgcacttaga cttaaaaact tcaaggcata taagagagat tagattaata
     2641 aattaaataa aatgtatcca aaagagctat ctttaaatta aaaggattaa tttacaaatt
     2701 aagatagctc ttttttcatg taaaattcac aacaataaga taaaatataa gtaatatacg
     2761 aaattttaaa taaaatagaa aggattgata gaatgaattc gtcaatactt gtaattgaag
     2821 atgattcaaa tatacaagag ttaatatcag aatttttaag tgcagaaggt tatcaagttg
     2881 atacagcaaa tgatgggttg gaaggtatac aaaagtttaa gcaaggaagt tatgatttag
     2941 taatattaga tataatgatg ccaaacttag atggttatgg agtttgtaaa atgataagaa
     3001 agtcatcaag cgttccaatt atatttttaa ctgctttaaa tgatgaagga gaccaactta
     3061 aagggtttga cttagaatgt gatgattata taacaaaacc attttcattt aatcttctta
     3121 taaaaagagt agaagcaatt ttaaggcgaa gtaacaagac tataaatgac aaatttatag
     3181 tttttgaaaa attaaaatta gatttaaaca catatattgc agagatagat ggagaaccta
     3241 tagaacttac actaaaagag tttaatatat taaaagcttt gatagaaaag tatccacaag
     3301 ttataactag ggaaggtctt ttggatagta tatggggtta tgactattat ggagatacta
     3361 ggattgttga tgcacatata aaaaatataa gaaaaaaaat atcattacca tatattaaaa
     3421 ctgtaaaagg aataggatat acacttgaga aggatatttg ataagtggga aaagttaagt
     3481 ataaagtata agttattttc aataacgaca tcattattaa tagcattagc tttaataata
     3541 tatctaattt tatatttttt attgccatca tattatcatg agtataaaat tgagtctctt
     3601 caagaaagtt tgaaatcttt agtagatagt tcaattcatt tcgatacata tactttagaa
     3661 gaaagacttt attatatggc taaagaccaa aatttggcta ttttattaaa agataaccaa
     3721 ggtaaaattg tatatggtaa gaatgaagta gttattttaa gatatagtaa gtacatgatt
     3781 aatagtcttg aggatgagta tagaacttct atacctatat atactaaaga tgcaaaagat
     3841 ggtccatata ctttagaact cgttatgcca ttacaaccaa ttgacgaagc aaacgaagtt
     3901 ataagaaaac taatgccata catcatatca atagcaatat tgatagcgat tattggagca
     3961 tatatatatt caattgtaat aacaaagcct cttataaaca taatagagag tgagagagaa
     4021 caggaatata gaaggaagga ttttgttgct acaatatcac atgaactaaa aactccaata
     4081 accataataa gtggtcaaat tgaaggtatg atttatagtg taggtaagta taaggatagg
     4141 gatacttatc tgaaaaaatc gtatgagtgt acacaagaat taaaagattt agtaaatgaa
     4201 atgatagagg tttcaaaatc agaaatactt gaaaaagatt tgaaattggt atcaataaat
     4261 ataagtgaat tattaaatag acttgtaaag agacaagtat ttttaataga agaaaaacat
     4321 atgaaaacta ttttaaaaat agaagaaaat ttggaaatta aagcagacca agagagaata
     4381 actaaggcaa tcaataatat aataaataat gccataaaat attctcctga agaatcagag
     4441 cttataatta gactctatga taaaaataaa cgaataagta aaaagacttc taatcaaaga
     4501 gtggttttag aaattgaaaa tactggtgta actatcgaga aacgttattt agaagaaata
     4561 tttaatccat tttatagaat agaaaaatct cgttcgagaa aaactggagg aagtggactt
     4621 ggactttata tagtcagcca aatttttaaa agtcatgggt ttgattatag cataaaaaac
     4681 aaagaaaact ctgtagtatt cacagtagaa tttaaaaatt aattacttat tataaagaat
     4741 atataacttt caataatagt tcattttaaa atcacaaaaa attcataatg aaactgtatt
     4801 atataaatat aaataagctt aaaaccataa aatacaccaa ctataatgat gagatttcct
     4861 tacatcctcc atataagtca tcattatagt aacccaacaa ttaagttact atgaatttaa
     4921 aaaataacac cgagcatata atctatgctt agtgttattt ttattttgaa ataaaaaata
     4981 tttaatttat tgaaatgtat agatttagat agtttaaact atatttaaga cttaaaaatt
     5041 ataattgata ttacaaataa atatatgtac tttgggaaaa ataaatatag gaagtattat
     5101 atttacagag gaggtagttt tgatggatag attaaaaaga gatatgaaaa atatgaaaga
     5161 agatttaaaa gaaggtgtta aaaagacagc ttatgttatg aaaaatacag ctgaagattt
     5221 gaaagatgat gcacaaggtg ctatggtaaa cttagaaatg aaaaaagatg agatgatgga
     5281 aagatatgaa caaaagaaat tttctaaaga attagagaag caaatgaaga atgaaatgaa
     5341 ataagctttt atttatgaat aacaaattat tgtattcata taaaaagtag ccagtaatat
     5401 taaatagttt atttaaggaa atagactttc taaaaataac tgtattagat ttagaaagtc
     5461 tatttcaaat tagttttata aatagacata aggataaagt agatgttata gaactagatt
     5521 ttaaaaaata gatactaagg ataaaataaa tattatagaa atatgttttt aagaatattt
     5581 atcaaataaa aatttatatt tataagaaat cctataaaac atataattaa acttataaaa
     5641 catttacatt aaattctgat aaaatatcta ctatatcagg agtaggcgtt ttttctgtaa
     5701 ttatagaact aatatcttct aaatgagcaa acttgaaatt tccatcaaat ttaaactttt
     5761 tatcttccat aactataaat acttttttac ttgaatttat tatagccttc ttcgtaagac
     5821 catcttcaat ttcaaaagtt gtaagtgaag agttgaatac atctactcca caacttccca
     5881 taaaagtctt atcaaactta tatttcgata taaactctat agttggagta ccgacaaaac
     5941 cgtctaaact gagatttaat aaacctccag tggaaattat atttaaatta tttggttttg
     6001 aagtaactac atttagtata tccagcatat ttgtaacaag tgttactttt ttattacttt
     6061 cagctaacaa cttcgcaagc aagatgttaa ttgtagagat atctaaaaat atagtttctc
     6121 tatcttcaat taaattaaat gctttttctg ctattatttt ctttgttgga atattaattt
     6181 cttttctgtc ttttgtatcc tgattctcta gtgtttctct agctagtaca gctcctccat
     6241 aaattcttct tattgaagaa atcttttcta tattttttaa atcttttctt atacaatctt
     6301 ctgtaacatt aaatttagaa ctgagctctt tgacagtaac tctaccttct ttttttagga
     6361 tatttaatat agcttggatt ctttcttctg caaacatttt ctacctcttt tcgcaatata
     6421 gtattatagt aaatattata agataaaata caatatatca actattttaa catgaaatac
     6481 aaaattaatt taatataaaa agtatgtttt ttctaactat atatttagaa tttagtaaat
     6541 aaaaaaatta taaaactaag aaggaaaagt aaaacaataa taaaaaataa aaaacaataa
     6601 gcaaaatgtt gaaaataata ccaaatcaat atataataag aataaagaaa gattaaaggg
     6661 ggatatttta atgcaactaa tcttagatac aggtaatgtg gaggagatta aggagttatg
     6721 tacttgttta ccaatagatg gtgtaactac aaatccaagt attgtttcaa aagaaaaaaa
     6781 gaattttaag caacttataa atgaaattgg tgagattata ggtgaggata tgcctataca
     6841 tgctcaagtg ttaagtacaa agtatgaaga aatattagaa gaagcattat atataagtag
     6901 tttgagaaaa aatatatatg taaaaatacc tgtaacacaa gatggtttaa gagctataaa
     6961 agaccttcac agaaaaggtg taaaaataac tgctactgca atattcactg ctcatcaagg
     7021 ttttttagct gcaaaggctg gagcaaatta tattgcacct tatgtaaata ggcttgataa
     7081 tatatctggt gatggagtag ctatggtttc agaacttata aaaataatag atacttataa
     7141 aatggataca aaagtacttg cagccagttt taaaaatgca caacaagtta tagaattaat
     7201 gcaacatggg gtgcatagtg ttacagtacc atatgatatt tgtaaatcta tgatgaatca
     7261 tccattaact gattggagtg taggtaagtt tatagaggat tgggagaata cttttggaaa
     7321 aggaagtaaa acaaataata tttagtatta tggtaaaaga gtagttttgt ccaatttcac
     7381 aagaacttat ataaaaagat gaaaatatga attttctttt taataatttc gttattatct
     7441 taagttaatt catattttca tcttttttag atttctagtc ctataaattt ccaccaaggg
     7501 aatgttatac atattattat aaagtaggtt aaaggaatca aagttaaacc gtatttgaaa
     7561 ataaccttgc tattatacag attttcacca tgaccaacca ttattgtagc atgatgaaat
     7621 ggtaatatgt actgtatgct tactataatg tagacaaata gacataaagt aacactattt
     7681 tcctttagta tatgtaaact tccaagtaac ggtattacta cagatgatgt agtgacagca
     7741 cttccaagac atatattcaa gattattgtg agagttatca aaaacaatat tgaaataatt
     7801 tctgaagagt ttggtataaa ctttatcaaa taatttccca ttatatctac aactccagag
     7861 tactttaaca ctcctccaat tgaaaatgct gctataaaaa aaataaggac cttccaattt
     7921 atttctttta aagtactaaa tccaactatt tttcttagta ataaaagaag tacacaaatt
     7981 gacattataa ttaatgtgtt tatgttatgt atgaactgag ttaaaaacat aaaaaacatt
     8041 attcctaggc ataaaaatac gtgtttttgc tctttgttta gcaaattaaa ttcttttttt
     8101 aaattagaat atgaaaaatg aagtttatta ccctcaagat tttcattaga aataaatttt
     8161 attgaatgca attctttttt aaagacaaag ataaataaaa aataagttat aaaacaagta
     8221 attatagttg gaacagacat ataaaaagcc cattgacccc aatttatatt acaatttcca
     8281 agttctagta caacataatt tagaagggtg tctccattta caaaaaacat tgatgtaaag
     8341 gtagatgctg taaatatact aaataaaagt atagattttg aatcttcagt tatctgttgt
     8401 tcttttaaaa actccttgta aaaagcagat acaagaataa cccttggaaa tggttgtggg
     8461 ataaaaaata ttaaaagtat acctaaaata tacgataaaa gaatcatttt tttaggggta
     8521 tttacagtat ttaaaattaa cttctcagaa ataatttttg cgacacctgt ttttgtaact
     8581 gcattagtaa ttatgtatgc aagaattatt atgtaaaaat tttctgtaaa taaaaactgt
     8641 aaaataacct ttattggtgc aatgttaaat ataaacgcta gaattacaaa aaacaatgca
     8701 acaaaagttt tttcaactga gtctacagcc catatcaaga tagttaaaaa agataagcat
     8761 atagaaaatt ttatgttgaa actgtaatta agagagaagt agagaattat ggtagctata
     8821 acagtcatat aaaattgttt tggcttaaga ataataccca tttttatatt cacctccata
     8881 atttattata tcataatgga ggtgaataca atgaatgtga atacatttta taaaaagatt
     8941 attcattgat tctatgattt acaatagctt tagttttcca atgtcctttc ttatagtaga
     9001 taactgtaac aataagacct aaagtccaac caaaaggaat acccatccaa attccgtctg
     9061 ttccaaaaaa tttagaaagc atataagaag ctggaagtct tccaagccat aaagatacta
     9121 ttgagcttat aagtgcaaac atggaatcac cagcaccttt cattgcactt gaaagtacaa
     9181 aagaagttcc aataaataag aagaatggtc ctattataaa taagtaagaa gagccaattt
     9241 taatgacatc tttatcagta ttgaatagag caattagatt ttccctaaat agcaaaatta
     9301 aagcaataac tgtaactgct aaaactaagg tcatttttat agattctcga atgccttttt
     9361 taactctttc attttctcca gcacctatgt tttgagcaac aaaagtagaa acagcagaac
     9421 caagattcat aataggtaag cttataaaat tttctatcct aagaccagca ccaaaagctg
     9481 ccatagcaga tgtaccataa ctattaacta aaaattgaag agccatattt ccaattgaaa
     9541 acaacatttg ttgaactcca cttggaagtc ctaatctaag tccatcttta aatattttgt
     9601 tatcatatac aattcctttg attttaaatt taagcacttc atgtttttta tttaaataaa
     9661 ttatacttat tataaatgat actgcctgag ccattatagt ggcaagtgca acgccctcaa
     9721 cacccattct tagcactaca ataaaagtta agtctaaaac tatatttaga attgtggcta
     9781 ttatcagaaa ataaagtgga gttactgaat ctccaagtcc tctaagtatt gcacttactg
     9841 aattatatcc agcagaaaat aatattccac taaatattat agtaagatac aattttgatt
     9901 gagcaaaaac ggattctggt gtattcataa gcttaagcat tgggccacca aatactattc
     9961 caagaatact tattaatata gaaccaataa ataaaagtat atatgtagta tcaatagtag
    10021 cttttacctt ttttaaatct cctgagccat aaaattgtga cactaaaata gaaaatccaa
    10081 ggctaacacc cataagcgct gccaccaata aaaacattat agggttagct ccagagactg
    10141 ccgccattgc ttcttttccg ataaatctac caactattat actgtcagct gtattgtata
    10201 gttgttgaaa taaactacca ataagcatag gcatggcaaa aaagaatatg gactttccct
    10261 catgacctgt agttaaatct ttcaccttat tcctccaaat aaaaaaatta ttaatttatt
    10321 atagtataat cttaacataa actttatatc caaactataa ataaattgta tcaaaatatc
    10381 atatattttt ttaaaatgta
//
LOCUS       DAEHWO010000118        10251 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEHWO010000118 DAEHWO010000000
VERSION     DAEHWO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.121"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            374..1534
                     /locus_tag="KNP54_003638"
     CDS             374..1534
                     /locus_tag="KNP54_003638"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBF0894495.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            1536..2666
                     /gene="glgD"
                     /locus_tag="KNP54_003639"
     CDS             1536..2666
                     /gene="glgD"
                     /locus_tag="KNP54_003639"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBF0894496.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            2695..4137
                     /gene="glgA"
                     /locus_tag="KNP54_003640"
     CDS             2695..4137
                     /gene="glgA"
                     /locus_tag="KNP54_003640"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBF0894497.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            4151..6571
                     /locus_tag="KNP54_003641"
     CDS             4151..6571
                     /locus_tag="KNP54_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBF0894498.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRVLL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            6576..8441
                     /locus_tag="KNP54_003642"
     CDS             6576..8441
                     /locus_tag="KNP54_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBF0894499.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIRIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            8686..9339
                     /locus_tag="KNP54_003643"
     CDS             8686..9339
                     /locus_tag="KNP54_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0894500.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPMEEMKKEKLL"
     gene            9435..10034
                     /locus_tag="KNP54_003644"
     CDS             9435..10034
                     /locus_tag="KNP54_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HBF0894501.1"
                     /translation="MYPNKEIAIEELEVAGKMNPGPWIKHSYNVANVAKLIAEQCENL
                     NSEKAFVCGLLHDIGRRTGISSVRHIIDGYDYVISKGWDEVARVCLTHSFPVKDIEAD
                     IGNKDISKEQYDFINHYLNNLEYNDYDKLIILCDALADANGFCILEKRFVDTTRRYGI
                     YPFSVERWNKTYEYKEYFEKIINKSIYTLLPNIEKSIYY"
BASE COUNT         4117 a         1003 c         1866 g         3265 t
ORIGIN      
        1 ccttggataa ttatttaaca aatattagat tatattttgc tattacgaat ttaacaaatt
       61 aaaaaataag catgttcata tgacacaaag gatttataaa aaatgttttt atatttataa
      121 aataaaattt gtattatttt ttaaccgata attgaatatt aataaatact atagtgctta
      181 tggaaaataa tgtatacgtc ggtaagtcca ttatggggta tacattatat caattgtata
      241 gttgatatta ttttattttt attaaggtat tatttaagca acatttatac acgacattta
      301 ttgactgata aagtttataa aagtaaaaat gcaattataa atattaatta ctagatgagg
      361 ggagtgtcat taaatgaaaa aagagatgtt agctatgatt ttggcaggag ggcaaggttc
      421 aagattaggt gtttttacaa aaagaattgc caaaccagct gtatcatttg gaggtaagta
      481 tagaattata gattttgtgt taagcaattg ttcaaactct ggtattgata ctgtaggtgt
      541 tttaactcaa tatagaccgt tgatattaaa ttcacatata ggcatgggaa gtcattggga
      601 tttggacaga ataaatggtg gtgtctatgt tttacaacca tttatgaatg aaaaagaagg
      661 aaattggtat aatggtacag cacatgcgat atatcaaaat atggactttg tagataccta
      721 taatccagaa tatgtattga tattatctgg tgaccatata tacaagatgg attatagcaa
      781 aatgttaaaa tttcataagg aaaaaggctc taaagctaca atagcagtga ttgaagttcc
      841 ttgggatgaa gcttcaagat ttgggataat gaatacaaat gaagattcaa gtatctatga
      901 atttgaagaa aaaccaagtg aacctaagag caatttggca tctatgggag tatacatatt
      961 tgattggaaa atgttgagaa attattttaa ggaagcagaa aaaaatccag aaataaatta
     1021 tgatgatttt ggaaaaaatt taatacctaa aatgttagaa gataatgttg gaatgtatgc
     1081 ttatccattt aaaggatact ggagagatgt aggaactata caaagtctat gggatgctaa
     1141 tatggatata ataaaatctc cagaaacact tgatttagca gaccctaagt ggaagatata
     1201 tacaaatact atggcaatgc ctccacaata tataggtaaa aatgcaaatg ttcatagatc
     1261 aatgatagct gatggttgta gaattttagg tgaagtaggt aactctgtat tatcacatgg
     1321 agttgttgtt ggtaaaggaa gtaaagtaat tgattcagta ataatgccaa atgttgtaat
     1381 aggtgaaaat gtaactatag aaaaagctat gataggtgag tgtgcaacta taaatgataa
     1441 tgttcagata aagaatgtaa ataatgaaat aaatgtagtt tctgagtatg aaaatatcga
     1501 acctagatgc gtattaatag aaggaggtct ttaagatgag aaatgaatgt ttagggataa
     1561 taaatttaaa caaaaaagga gacccagcaa taaacaaact taactatgga agaccaatag
     1621 catctacacc aatagctgga agatatagaa taatagactt tgctttatct aatatgataa
     1681 attcaggaat cactaaagtt ggaatattcg caaaagaaaa atacagatca ttaacagacc
     1741 atataggtag tggtaaagat tgggatttaa gtagaaaaaa aggtggccta tcaattttta
     1801 gtccagaaaa cactaagtat agaaatactt actcacatag agaaggtgat atatatacta
     1861 tcttagctaa tctagattat atagaaaaga gtgaagaaga atatatttta atagctccaa
     1921 gctatatgct atgcaattta aattattctc aagcattgga ataccataaa aaatctcata
     1981 atgatataac tataatatat aaaaatgtaa ataatgcaaa taaagatttt gctggtaact
     2041 taactctaaa tttagatagt aacaataggg taataaatgt aggaaataat ttaggtaagt
     2101 tccctagagc aaacatatgt atggagacat atattatgaa gcgtgaagat tttgttgaat
     2161 gtatatataa cattgtaaat aaaggcaatt attgttattt agaagaattt attattgaag
     2221 aagcagaaaa catgaaaata ggagcctatg aatatacagg atatctaaaa tgtgtaaatt
     2281 ctgttgaatc atattttgaa atgagcaaag atttattaaa tttagaagtt gcagatgaat
     2341 tattatattc tgaaagaaag atatttacaa aagaaaagaa tgaatcacct acaatttata
     2401 cagatagtgc taaagtagaa aatagcttta tagcatctgg ttgtttaata gaaggtactg
     2461 taaaagatag tatcatattt agaaaggtaa atgttgaaaa aggaacagtt atagagaact
     2521 caatagtaat gcaaaattgt gtaataaagt caaatgcaaa actatataat gcaatattag
     2581 ataaaaatac aagtgtatca aatgggaaag aattaagagg agatgaaaaa tatcctcttg
     2641 tagtggaaaa gaatacaaat atataaataa attttttaga agggggaatg actaatgaag
     2701 gttttttatg taacagcaga gtgttggccc tttgcaaaaa ctggaggatt aggagatgtt
     2761 tcttatgcat tgcctaaaga attaaaaaaa gaaggtgtag atgtaagggt aataatgccc
     2821 aaatattcaa ctataccaag ttatttaaaa gatcaactaa aagaaatagc tgtgtttagt
     2881 gtacgtgttg gatggagaaa tcaatactgt ggtcttttag aaatggaatt ggatggtgta
     2941 aaattttact ttatagataa tgaattttat tttagaagag aagatgaaag aaagagtatc
     3001 tatggatatg gagatgatgc agaaagatat actttcttta cagatgcagt tttagaagct
     3061 ataagtagaa ttgattttta tccagatgta atacatataa atgattggca tacagggatg
     3121 ttaccattaa ttctaaaaga aagatatgca acccttgagg ggtataaaaa tataaaaact
     3181 atgtatacta tacataatct ccaatatcaa ggtgtatttg ataagcatgt tttatatgat
     3241 atattggact taccacaaaa atactttgat aatggagata tagagtatta tggctcaata
     3301 aattttatga aagctggtat aaattttgca gataaaatta taactgttag tcctacttat
     3361 gcaaatgaaa tacaaacatc tttttatggc gaacaattag atggattact tagaaaagag
     3421 tcaggaaaat taaaaggtat attaaatggt atagattatg atttaaatga ccctgcaaaa
     3481 gataaagata tatttgttca ttatgatgta gactcaattg acaaaaaagt agaaaataaa
     3541 ttgagattac aagatatatt gggactaaaa aaagattcat ctattccgtt gataggtata
     3601 gtttcgagat tagtttctca aaaaggattt gatttaatag catacatgat gccagaactt
     3661 atgagagaag atttacagat tgtcgtttta ggaactggag aacatcaata tcaatcaatg
     3721 ttcaactatt acgattctaa tttttcagat aaagtatcag ctagaattac ttttaatgca
     3781 tcattggctc aacagatata tgctgcaagt gatatgttct taatgccatc attatttgag
     3841 ccttgtggta taggtcaaat gttagctatg agatatggtt ctttaccaat agttagagag
     3901 actggagggc ttagagatac agtaacacct tataataaat ttactggaga aggcaatgga
     3961 tttagtttta aaaattacaa tgctcatgag atgtttttct gtttgaaaaa tgcaatcaaa
     4021 gtatttaagg acaaagaaaa atggattaaa ttagttgaaa atgcaatgaa aacagataat
     4081 agttggaaaa aatcagctaa ggagtatata gaaacatata gagacatatg tgattaaagg
     4141 agtggttttt ttggtaacaa taagcaaaaa gaaattcaag caaaaatttg aagtaaaaat
     4201 gtatagctta tatgcacaat ctatcaagga agctactgat gaacaattgt taaatgtatt
     4261 atgtagtcta ttgaaagatg agatagcaaa aaaatgggtt gctacaaagt tagataagaa
     4321 aaaagaagtt tattatttta gtttagaatt tttaataggg agacagttaa aatctaattt
     4381 attaaattta aatattgaag aagaagttag agaaggttta tctgaattag gaatcaactt
     4441 ggatgattta attgaagctg aagtagaccc agccttagga aatggtggac ttggtagatt
     4501 agcagcttgc tttttagatt ctatggcatc tttgaacata agtggtcaag gatatggaat
     4561 aaggtataaa tatggtctgt ttgaacaaaa atttgtaaat ggttatcagg tagaagtgcc
     4621 tgataactgg cttacagaag gacgatatgc atgggaaact gtaagaccaa atgaagcaac
     4681 aatggtgaag tttggtggtg aggtagaatt aatcaaggaa ggtagtcatt taaaagtaat
     4741 tcataaaaac taccttcctg taatggcaat gccttatgat ataccaataa tcggatacca
     4801 aaaccaatgt ataaatactt taagattgtt taagagtgaa ataccaaaga gagattttgg
     4861 tgaacttacc tcaaatgctc taaattattc tggtagctat gaagaggctt taaaacataa
     4921 gtattatact gaggaaatat cacaggtatt atatcctgat gattcaaact atgcaggtaa
     4981 gttgttgagg ttgaaacaag aatacttttt tgtaagtgca gggatacaag atataataag
     5041 aaaatataaa aagaacaaat taaatattaa taatttattc gataaggtag caattcatat
     5101 aaatgataca catcctacct tatgcatacc agaacttatg agagttttgc ttgatgaaga
     5161 aaatttatct tgggatgaag catgggaaat aactaaaaaa acagtgtcct atactaatca
     5221 tactataatg tcagaagcaa tggaaaaatg gcctgtaagt atgatgaaag aactattacc
     5281 aagaatttat atgataatag aagaaataaa tagaagatat gtagaggaat taaataataa
     5341 aggatatgac caagatagaa taaaaagaat gagtataata gactgtgaca atatcaatat
     5401 ggcaaactta tgtattgtca caagtcatag tgtaaatgga gttgctaagc ttcatactca
     5461 tattcttgaa acagaggtat taaaagattt ctatcaagat gaaccaaata aatttaataa
     5521 taagactaat ggaattgcac ataggcgatg gcttataagt tcaaatcctc aacttagcaa
     5581 tttaattaca gatttaattg gtgattcatg gaagaaagat acattacaat taaaaaatat
     5641 tgaaaaattt aaaaatgatt cctctgtttt acaaagactt gatgatataa aatacaataa
     5701 taaagcaaat ctagcaaagt ttataaaaga taaatacgat ttaaatgtag acccaagttc
     5761 gatatttgat gttcaagtta agagattgca tgcgtataaa agacagttac tgaatatatt
     5821 taatgtactt catatgtatc atgaattact tgataatcct aatttgaatc ttgacccaag
     5881 aacttttata tttggcgcaa aagcagcacc aggatattat ttggctaaat gtataattaa
     5941 atttataaat tctgttgcaa gtactataaa taatgatgtt agagtaaagg acaagttaaa
     6001 agtagtattt ttagagaatt atggagtatc attagcagaa ataataatac cagcagcaaa
     6061 tgttagtgag caaatttcaa ctacaactaa ggaagcatct ggaacaagta atatgaagtt
     6121 tatgatgaat ggtgctataa ctttggctac acttgacggt gcaaatgtag agatatgtga
     6181 acaggttggt aaagaaaata tgtttttatt tggacttagt gcagaacaag tactaaatta
     6241 taataaatat ggtggatatt cttcacttga cctatatcat tctaatatgg atataaaaag
     6301 ggtagtagat gatttaataa atggatttat tcctaatctt ggcgaagaag gaagaagtat
     6361 ttataattca ctcactactt acaatgatga gtattttgta ttgagagatt ttgaaaatta
     6421 tggtcaagct caagcagata taaacaggtt atatagagat aaagaaaaat ggaataaaat
     6481 gtctttagtt aatatagcta attctggatt tttttcttct gatagaacaa tttctgagta
     6541 tgcaaaagac atttggttta aaagggtgtg attaaatgca aagtgtaata gaatataact
     6601 cttgggataa aaattttaag gctccgtttg gagctttaaa atttgatgag gaattgacca
     6661 tttgtgttaa agtaaatgag ggatacaata tcaagtctat ttccctagaa ataaatagag
     6721 aagaagaaat gagaacaata actttaaatg aagaattaga taatgataaa cttggaaagt
     6781 gcttttgtgg taagattgaa aagtttgatg gtacaggtgt ttatttttat tactttaaag
     6841 ttgatgttga aatggatggt cagataaaga ctttatttta tggaaaaaac agagataatg
     6901 gatattcttg tgaatataat tatagtgata ttaataaata tcaaatcact gtttacaaag
     6961 attttaaagt accaacatgg tacaaagaag gaatacttta tcatatattt gtagatagat
     7021 tcaataatgg aaatcgtagt ggtaaggttg ataatcctaa aaaaaatagt ttcatatatg
     7081 gaaattggga agatacacct atgtacataa aggatagtca aggggatgtt ataagatggg
     7141 atttccatgg tggaaattta agagggataa tcaataaact tggatattta aaaaaattag
     7201 gtgtaagtat actatatcta agccctatat ttgaagcctc tagtaatcat aagtatgata
     7261 caggtgacta taaaaaaatt gacccaatgt ttggggatga agatacattt aaagaactta
     7321 ttgataaagc aaaagaaaaa ggtatatcaa tagtattaga tggagttttt agtcatactg
     7381 gagcagatag taaatatttt aatatgtatg gaaactataa tagtttaggg gcatatcaat
     7441 ctaaagaatc tccatattat tcatggtata tgtttgaaga atttcctcaa aaatataaaa
     7501 gttggtggga tgttaagaca ttgccaaata taaatgaatt agaacatagc tatatggatt
     7561 atataatata tgacaatgat agcgttataa ataaatgggt aaatatgggt attaagggct
     7621 ggagactaga tgttgcagac gaattaccaa ctaagtttat aagagagtta aaaaaggaat
     7681 taaaaaaggc agatgatgac tcaattctta taggtgaagt atgggaagat gcatcaaata
     7741 agattagcta tggtcagaga agaagttatt tattaggtga agaattagat tctgttatgg
     7801 gttatccttt tagaaataac atgttttctt tcttaaaagg agaaattaat tcatatgaac
     7861 tttgtaatag atatatgcag attaaagaaa attatccaaa agaatcattt aggtctaatt
     7921 taaatttaat tggaacacat gatgttacaa gagctaaaac ggaattaaat gatgatgtag
     7981 atttagtgaa gcttgctgta gctatacaga tgacatttga aggagtacca tatatatatt
     8041 atggagatga agcaggtctt tgtggaggtg ttgacccaga taatagaaga acttatccat
     8101 ggaaaaatga agacgaagat atgcttaatt tttatagaga tgttataaga attagaaata
     8161 agaataaact tttaagttct ggaaatacag aatttatata tactaataat gattctgtat
     8221 tttcttttat tagagttaat gaaaataatg atagaatgtt aattttagta aatagaagtg
     8281 aaaatgtgga aagtatatca ttatgtatag agagtagttt tattgaggaa atacctataa
     8341 agtatagtct taaaaatgca aatagtacta tacaaattga aaataatgag ttgaaagtag
     8401 atttagactc taaatcattt agaattttta gagtaaatta aatatctttt tttagaaaaa
     8461 taaatagaaa ataaggtgaa tgtggaaaga gttttgtttt atcaaaactt tttctacttt
     8521 ttttgtataa attatcataa gaattttagt atttcaaaat attacaaaga agtataaaaa
     8581 atatcataat tgtgatatta tataaattag taagataaaa ctgaactctc taccaaagtt
     8641 gtagggagat ttaactttta taatcttaat atggaggaac gtcttatgaa ggtagatcca
     8701 cttacaactc aagtatatga ctatatatca aagaaaatcc aaaatggaga atatgaagct
     8761 aatcagagaa ttactgaatc tgagatttgt aaatctatcg gagttagtag aacaccagcg
     8821 agagaagcat taactaggtt agcaggtgaa aatttactag aaaaaatacc taataaggga
     8881 tttgtagtaa aagaatttca ggaaaaggag aaattagaca cctattccgt aattggagta
     8941 ttggatgcgt tagccggttc ttcagcatta caaaatttaa ctgaatcaga cctagtaaaa
     9001 atggaagaat taacagaaat gatggcggtc tctataaagt ataaaaatta caatagctat
     9061 ttaaaattaa gtaatgaatt tcacgatata tacataacta aatcagataa tcaggtgtta
     9121 gtaaatctat tgaactcttt aagatataat tttatgtcaa agtcatatac tagtgataat
     9181 gaagatgagt tatataaaat gttgacatac agcaataatc aacatattga agtagtaaaa
     9241 tctatgaggg agaatgattt agaaaatgtt gaaagaattt tgagagaaca ttggaaaacg
     9301 atacctatgg aagagatgaa aaaagagaag cttttataaa gtttctcttt attttttata
     9361 ccattttatc actatttttt tgaattatta agtagaaaat aataattaat ttaaacttga
     9421 ggaggaaaac taatatgtat ccaaataaag aaattgcaat agaagagtta gaagtggctg
     9481 gcaaaatgaa tcccggtcca tggataaaac attcttacaa tgttgctaat gtagctaaat
     9541 tgattgcaga gcaatgtgaa aatttgaata gtgaaaaggc ctttgtatgt ggattattac
     9601 atgacattgg aagaagaact ggtatttctt ctgtaaggca tattattgat ggatatgatt
     9661 atgttatttc taagggatgg gatgaagtgg cgagggtatg tttgacacat tcttttcctg
     9721 ttaaggatat agaagctgat attggaaata aagatattag taaagaacag tatgatttta
     9781 tcaatcacta tttaaacaac cttgaatata acgattatga taagttgatt attctttgtg
     9841 atgcattagc agatgcaaat gggttttgta ttttagaaaa aagatttgtt gatacaacac
     9901 gaagatatgg aatatatcca ttttcagttg aacgatggaa taagacttat gagtataaag
     9961 aatatttcga gaaaataatc aacaagtcta tatatacatt gttacccaat attgaaaaat
    10021 ctatatatta ttaaatccta agttaataat ttaatatcca gtatcaccag cagttggtca
    10081 ttatgattga ctgcttttat tatgcttata ttaaaaaaat acactatggt ttgtgtatat
    10141 caaagttata tggaatgaaa agagaattta ttttatcaat taaaaaattt aataaatttt
    10201 atattaaaat taaaatacaa aaataggaaa attatttagt ccaactaaac c
//
LOCUS       DAEHWO010000119        10104 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEHWO010000119 DAEHWO010000000
VERSION     DAEHWO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10104
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.122"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            172..1053
                     /locus_tag="KNP54_003645"
     CDS             172..1053
                     /locus_tag="KNP54_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBF0894502.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            1038..1411
                     /locus_tag="KNP54_003646"
                     /pseudo
     CDS             1038..1411
                     /locus_tag="KNP54_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(1671..4238)
                     /locus_tag="KNP54_003647"
     CDS             complement(1671..4238)
                     /locus_tag="KNP54_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBF0894503.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYMSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(4241..4846)
                     /locus_tag="KNP54_003648"
     CDS             complement(4241..4846)
                     /locus_tag="KNP54_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0894504.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLNGIMNDGGE"
     gene            complement(5220..6680)
                     /locus_tag="KNP54_003649"
     CDS             complement(5220..6680)
                     /locus_tag="KNP54_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBF0894505.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRGNIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            7050..7628
                     /locus_tag="KNP54_003650"
     CDS             7050..7628
                     /locus_tag="KNP54_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0894506.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            7919..9169
                     /locus_tag="KNP54_003651"
     CDS             7919..9169
                     /locus_tag="KNP54_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBF0894507.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            9330..9899
                     /locus_tag="KNP54_003652"
     CDS             9330..9899
                     /locus_tag="KNP54_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBF0894508.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3388 a         1736 c         1478 g         3502 t
ORIGIN      
        1 aagtttcatc taattataaa ttggacaatt tttatgttga ttttattcat acaaattaaa
       61 gtaacttata aaatctccac aataaaaaac attttttatt cactaaactg ctccatcatt
      121 ggtttagcaa taaatatatt ttttaggtct ttaatgtcaa tagtgttaaa tatgccagca
      181 tatttatttg atagtaattc tattgcaaat atttacagag tatttcctat atcatttagc
      241 tttatagtta caggactata tttcagttat aaaaataata aaaataataa gattaacttt
      301 gaggcagttt tagaggacaa aaaaaactta attttcttat tgagccttat gtttggaatg
      361 tacttgtatc tatgtttgag tttgtcaata tactatactg ttggaaatgt attgatttta
      421 aaattatatg gaatcaagtc tgccataata gttttggtag gtaactatat tgcagaaaga
      481 tatagcttta gaattactca aataaaaggt tatgatatta aaaatcaaat agaatatgta
      541 gaaagtgtaa agacagaata tgagattaat aaattgaatg atattgtata tacagattta
      601 ctgacaggtt tctacaatag accttttgtg aatcaaaaac tatcagaatg gacatcaaat
      661 cactacaaat ttaccttatg ttttactgat ttaaatagct taaaacctgt aaatgataaa
      721 tttggacacc aatttggtga taaatacata tccactactg ctcaaataat aaaaaaactt
      781 ataaatgtag aaaattcctt actatttaga tatggtggag atgaattttt attcctttta
      841 cagaatacaa gttgtgtaga agcagaaaag ataatgatta atataaatta tgaattatca
      901 aaattaagta atactgacga gtatccttat gctctttcca taagctatgg attagttgag
      961 tgggatggaa tatccgatat tgaaacttta atatcaaagg cagattcttt gatgtatgaa
     1021 aataagctta aaaataaatc tactttaaac tagctagtta agatattcta caaaatatat
     1081 gttataagag agtactaaga atatcaaaat atatagattt tgcaaatatt gaatacagtt
     1141 tactaatgaa tgcactggat gtaagtgtta gtaaacacct attagatgaa cactttactg
     1201 ttgtttgggc taatgaccgt tattatgaaa tgttcagcta tacctagcta aaaagttaaa
     1261 aatgaccact gtagccgagg gaatagagac cagttttcaa aaagatttct tgcaagaaat
     1321 aaactgtgat atgttacaag gatacgtgtt ctctagacct ttaccaataa aagactttga
     1381 aaaacttatg tttcaaaact cctccaatta acaatataaa attgcttatt ataagtgata
     1441 ttattgtatc aacaaataaa ggaattgtct caaaattgat tttttctaat caaattttta
     1501 ttttgagaca ttctcatttt tttgcataag aaaataccca ccaagctacg gtttttctta
     1561 ccgctgttcg gtgggtatta gtagtattat gaaatctgaa aactttaagt attactactt
     1621 ccgctaacgc aatcacaaag gtcgaaagct tcaaagcgaa aataggcttt ttactcatca
     1681 aacgtcaccg tacctgccaa cccgtccacc gttatcattt gtccgctctt aatagttcgt
     1741 gtggcaatgt gtgtagccat aacggctggg atgccatatt cacgtgcgac aatgcttgaa
     1801 tggctaagag gaccaccaat gtccgttaca atcgcacttg cagatgaaaa taatggtgtc
     1861 catgctggag ttgtggtaac tgcaaccaaa acacttccag gttgaaagct ttcaaaatct
     1921 gctggactat tcagtacaca agctggagcc gtcacaacac cagtactggt accaatgccc
     1981 gtcaacacaa ttttcccatc tttctgcttc tgttgtgctt gtgatatagt ttttttgttt
     2041 ttctctggca acttggatgg tgacatataa cccatgtatt ttttaagttc agcttttcga
     2101 acaggtatta tcccgttcat atcagataga gacttgtttt tatccaactg ctctataagt
     2161 acctccaatt ccgattttgt gagccaataa atatcatcta aatgtgaaat agctcctcct
     2221 cgtatgaatc gttctgagat ttcctgaaac atacaacgaa tcagaggatg tcccattccc
     2281 atcaaataaa tagcattttc acgcatagga gaggtttcct gtgcccaatg gagcaactta
     2341 aaaaatagtt ttttacgcaa tccacctatg tgttgtaaaa tctcttcttc tgcatgtttt
     2401 ctacgctttt caaacgtggt ctggcgtaaa aaaggacttt ccccttttcc ttccacaaat
     2461 gtttttacgg attcaaaagt tggtgtaagt gtttcctgcg gtgtggaatg cgcaaaatca
     2521 aactcataag cggtacgacc aaactcttta aagtacttat tgattcgatt tttccattct
     2581 atccatactt cctgtgaaac tccaacaggc acaactgaag acatgaaatc ttctgctatc
     2641 tttattgcag gactgttttg cagataaagg ttgatgctgt tattttgctt tacccattct
     2701 gaaatacccc acaactcctt ttccgattgc agaacaatcg tatcaaaccc aagcaggaaa
     2761 acggaagtat ccgttatacc agcacgtcga actgctcctt gaaataattt tgtaaataat
     2821 gtttcactga tagaagcagc aggcaatgta agctgaatcc ttgtgaaata aatacatgcg
     2881 gcataaaata ttgtctgaat accctccata atttgatggg cgttcatagt atgcaggggc
     2941 ttttcttccc attgtttaat agcatcctca tatccttttc gtgccgtttc ccagcgtgca
     3001 acgctgttca taagtgtcct acgtaaagag cgtggggaaa gggatttgat agcaatcaaa
     3061 agtggctttg atttagcaga aagataaaca tatccattaa taaccgtata tgccccgttt
     3121 tttggtaata attttttcgc acttttacca aacatatcta tccataaaag ctctgatgca
     3181 cggtttacga tttcaagacc aagtgtggcg aacaaaggtg taacaggatt tggcaaatgt
     3241 tctgccaaac ttccctttgt gtatacaaca tcctgttctg gcaataccca ttctggtggc
     3301 agaacagtaa ttggacgagc ctgaacaatg tacaatttat ctttttccag tgcccactct
     3361 acatccatag gcatttgata atacttctca attttctttc caagctgtat cagttgcatt
     3421 acctgattac gagtaagagc atattttttt ctcaaccttt caggaaccat ggtttcttct
     3481 gttccttctg aagtacgaac cgtcataatc tctttatttg ccacttcata cgatataatt
     3541 cgttcggagt ccttatccac tacgattgta tcgggtgtaa ctaagctaga aaccaccgct
     3601 tcaccaagcc cccatgcagc gttaataatc atttcgctac gtctaccatt gattgggttt
     3661 aacgtaaaca taataccaga tgaatcggaa aatgcaagct tttgtactac aacagcaagt
     3721 gcgacaatct cgtgctttat attattcttc acacgataag caatagcacg agctgtccat
     3781 aaggaagccc agcatctctt tacagagtca ataactttat cttcaccttg tatgttaaga
     3841 taagtttcct gctgacctgc aaaagaagcg tcaggtaaat cttcagcagt cgcagacgaa
     3901 cggacagcca ccgatatgtt ccctaatcca gcataagcca ttttaattgc gtccgacact
     3961 tcctgtggca tttctccatt atggaaaagc tcccctattt tcttagatac atcttcaagt
     4021 tggctggtat tattggaatc aataccatct agcagtttat taattcgaga ctgaatatgg
     4081 ttcgtctcaa caaaaatctg gtatgaagca gtcgtaacat gaaaaccgtc tggcacaggg
     4141 atgcctgctg tcaatagttt tgataaagac atcccttttc caccaacaat ttcaatggtt
     4201 gcttgtttat gttccagtgg caagacataa taaatcataa tcattcacct ccatcattca
     4261 taattccgtt cagaaatata ttcattgttt catccaacat tttttccgaa ctatccaatg
     4321 gtcgtgacgt gtagctgatt gataacatgg agttaattaa caaacgtgtc acaagagcgg
     4381 tatccgtttt gcgaaagatg cctgtggtca caccattatc aattaccgat tttataatat
     4441 cttgatatgc ataacgagca tctttaagtc tctttcgata ctcttcttct aaataatcag
     4501 attctgtatt taaccacatc agtacagttc tatactgctc tggaaatcta agatgattaa
     4561 gcatgatttt tctaaggcac tgttgtggtg aaggttcacc atcaataatc ctatgaactt
     4621 gttggatagt tttttctatt tctttctcaa ctgcatatac aacaatctcg tctttcgttt
     4681 taaaaaaatc gtatagactt gactttccca tgttggctaa aactgcaatt tctctcattg
     4741 atgttttttg gaatccattt tcagccatga gactcaaagc aacagcaact attttttctc
     4801 ggcgttctgc ttgttgttcg ggtgtaagca caattccttt tggcatagtg cgatacctcc
     4861 ttttagcgac cactggtcgt ttctttttta tttatcatac agcaaccaac ggtcacttgt
     4921 caaggttaat ttttttcatt gtatatggta ctcgagataa aaatgttcat tttagaaatt
     4981 actctattta agtagaaata ggcttcatca ttagaaagca agactataaa tttgagatat
     5041 ttatcatgtt caaatttcat caatatcaaa gtttaaaata ttaataaaaa aagaattact
     5101 aagaaataac atataaagat tcaaaaaagg agttgaactt aaaattcaat tacaaaaaat
     5161 caaatttaag acaactcctt tattctttat ctctactatt ctttatctct atttatttat
     5221 tacaactccc taacatttac cactactgcc ttaggtctag tcatagcctc aattgaatac
     5281 ttaacacctt gagttcccat accagatgcc tttacaccta aaaatgggaa gtggtctgga
     5341 cctctttcag tcttattatt tatttgaaca gtaccaactt caagtttatc agctatataa
     5401 aatgccttat caatatcact tgtaaatact gatgattgaa gcccatactc tgattgatta
     5461 gcaatttcaa ttgcttgatt tatatcttta actcttataa ttggaagtac tggaccaaat
     5521 ggttcttccc aagcaatttt catatcaaca tttacattat ctaacaatgt tggatagaat
     5581 aaattatttt ttctaacatt gcctgttatt aactttgctc ctttatgtaa tgcatcatca
     5641 accaaccctt gaacaaaatc agttgcttta ttatctataa gaggagtgat aactacttca
     5701 tccattggat ttccaattgt caacttctct accaatggct ttatttttcc gactaattta
     5761 tccgccacac tctcttgtac taaaattctc tttactgccg tacatctttg tcctgaatat
     5821 gaatacgctc cagatactat attcttagct gcaaaatcta agtctgcatc ttctaatact
     5881 atagccgcat cttttccacc aagctccaat aataatggta ccattccaga tattttagat
     5941 atatgctgac caacttcagt actaccagta aagttaataa aattaattcc tttatgcgtt
     6001 acaacataat cccctatctc actaccccta cctgtaatag tattaagtac tccatctggt
     6061 atcccagctt ttctcataat ttctaccaca tgaagtgcgc taatagcccc ttgtgtagca
     6121 ggttttaata cgactgcatt tccaccaata agtgctggag caatctttga cattgataaa
     6181 tttacaggat aattaaaagg agatatagct aaaacagtac ctaatggaac ccttgaaaca
     6241 taagacatct tatttcttgt tccaccaggg aaattatctc cactaatggc ttctccctcc
     6301 atattttttc ccacatcagc tgtgtatctt aaaaaatctg ctgttctctc aacttctgcc
     6361 cttgcagatt ttatgtcttt ggctatttca agtaccagta tattagctat ctcatctata
     6421 ttttctaaca ataaatcagc agccttatga aatatattgc ctctcttgta tacaggcatt
     6481 tcagcccata cttttatact ctcttttgtg ttttttataa cctcatctac ctcatgtttt
     6541 gtcatagatt gtactttccc aacaagagaa ttatctattg gtgagtaaat ttctattggc
     6601 tttctcgaat tagattctac ccattttcca tttattaaat ttttatatac attttctttt
     6661 gttttaagtt cattaaacat atttttattc ctctctctga tataactttg tgtatttaaa
     6721 ttatagccat ttattcgtta tgtaaacatt tctttttttc ataaacgttt acctataaaa
     6781 aaattttaag ttaacgtttt tctacattct tctattttaa taacatactc gctccaaatc
     6841 tatataggtc acactttaat actaatatat caatatacca atataccaat ataccaatat
     6901 accaatatac caatatacca atataccaat ataaatatta taaacataaa tcacttgaca
     6961 aatttataag tagacaatat tatatatcta tgactcaaaa tatttttaaa gtcatatata
     7021 tcatatatag acagaaagga ttgataaaaa tggctaaaag ttttacagaa atagaaaaag
     7081 acaatataag aaaaagacta atttcagaat gtgaaatcaa ctggtctaaa tatggataca
     7141 aaaaaactaa tattgatgaa ctttgttcaa aatcaggaat tgcaaagggt tctttctata
     7201 cattttttga ttcaaaagaa aagttatttt ttgaagtatt aaatggaatc caaaacagac
     7261 ttatatcatc agtagatgaa attttaagta acatgcctcc aaaagaaggc tttgcaaaat
     7321 ccttaaaaat gttatatcga ttatatgata aaaatccatt tttatattca ccaaataatc
     7381 ctgatttcat cagcctaata aataaactac ctcaagatat gtttttacaa cttgagtcca
     7441 ataacataca aagtttttac gacttaattg agagacacaa tctcaagttg aagatagaaa
     7501 aagaaaaagt ttttggtgtt tgtaatgctc tactatcaag tctgttggta aaagaaaata
     7561 ttgaatataa ctatattgaa gtgtttgact ttatggtgga taatcttgta gaacacatac
     7621 ttgaataaca atttaaaata atttttctaa gtattttttt atactaaata ggattaatat
     7681 gattgaatta atgcaaaaaa taaacaatat aatttataaa ataaatgata aactaaatat
     7741 cacacaaaac ttatagaccc tagagcaaac ccattccact ctactctaag ccatctataa
     7801 tagtttgtat atttctaata atattagata ttaaagtaag aaaaaaattc cttataataa
     7861 ttgctattat atcaattatt gtaaatgttt taataatctt agataggtag gtacatatat
     7921 ggtaaaatcc tcgaacactt ttaataaaaa cttcaacttg atgatattag gtcaaataat
     7981 ctcattgttt ggtgcatcaa tacttaaatt tgctttatct ttatacatac ttgatataac
     8041 tggtaaagca gaaatatttg ctactatact agcagtatct tcaatcccaa ttatagtatt
     8101 ctcccctatt ggtggagcta ttgcagatat attcaacaga agaaacttaa tggttatttt
     8161 tgatttttca agtagtctta cagtactaat cttagcagta ttcttattca acaataatgg
     8221 ttcaatatta cttgtaggaa ttattatgac catattatca gtcataagca caatgtatca
     8281 accaactgtt cagtcaagta cacccctttt agttgataat gagcatttaa tgaatgcaaa
     8341 tggtattgta gctggagttg catctcttac aaatattgca ggacctgtat taggaggtgt
     8401 cttgtatggt gtgattggaa ttaatgcaat tatagttata agttgtgtaa gtttctttct
     8461 atctgcaatt atggagatat ttatacagat tccttttatc aaacaagagc aaaacagcaa
     8521 cattataaaa actatattta ctgatataaa ggatggtatt gttcatatat gtaaagaaaa
     8581 tagatttata ctaaaaatac tttttttagc tatagcaata aacttatttt taagctctat
     8641 gttaatagtt ggtatcccct atatagtaaa aatcactatg ggagctagta acttcttata
     8701 tggtctagca gaaggagcaa tttcttttag ttcactggta gctgctgtta gtattggtat
     8761 tttctcaaaa catctaaaaa tcactaattt gcatatttcc tttattatat gtgcagttat
     8821 gttcatacca atggcggttt cagtatatcc atttatatta aacacaggat ttccagttcc
     8881 atttttaatc tttatagtat catctatgct aatatttttt acaacgactc ttatctcaat
     8941 atatgttata acagtcacac aattaaaaac tccaaatgaa ctcttaggaa aagtaatgtc
     9001 aattcttttt gcaggaacag caattgcaat gccccttggt caggttatgt atggtaaact
     9061 ttttgattta ttatcagata gagtgtacat cattatacta ggagttggat ttattacatt
     9121 acttatagca tttgtatcaa agataacatt gaggaacgaa aatctttaga tacaaagaat
     9181 ttagatataa agatttaatt ttcactaatt tctgaattta aatgcaaaat tgtgtatcag
     9241 tatgttgacg ttttagaaat tgattgatat aatcaatgga aaataaactt tataaaaatt
     9301 caaaatattc agctagagga gtgataaaaa tgagttacat gccaacttta gaacaagcat
     9361 gggaaatatt aagaaaatac aataaggaag aatttcatat aagacatgct caaattgtat
     9421 ctggagttat gagatactat gcaaaggagt acgaccctga aagagtagaa ttttgggaaa
     9481 tagttggact tttacatgat ttagattttg aaatgtatcc tgatgaacat tgtgttaaac
     9541 aaagagaatt aatgacagag cttgatttag ataaatcaat aatcgattct acaataagtc
     9601 atggatatgg attaactggt tcagatgtta aaccagagca atttatggag aaagtattat
     9661 ttgctgtgga tgaacttact ggtttaattg gtgctgctgc aataatgcgt ccttcaaaga
     9721 gcgtttctga tttagaatta aaatctgtta agaagaaatt taaagataaa tcatttgctg
     9781 ctggctgttc tcgagacgtt ataagaagtg gtgcagaaat gcttggatgg gaacttgata
     9841 agcttatcca aacaactata gaagctatga gaagcttgat tccagagatg gcaatatagc
     9901 tcctccatac atataccata gaagttacat ctttaaagag catttctctt tttgatgcaa
     9961 cttcttttta tattttgtag aataaaaagt ttaatatttt aaactcacta tataataaat
    10021 aatataatgt ataatagtca taaactttct aaccttaaaa gtttctaata atcaataaac
    10081 aattctaata tacaaatgtc atta
//
LOCUS       DAEHWO010000120        10076 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEHWO010000120 DAEHWO010000000
VERSION     DAEHWO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10076
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.123"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(76..546)
                     /locus_tag="KNP54_003653"
     CDS             complement(76..546)
                     /locus_tag="KNP54_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBF0894509.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
     gene            complement(1416..1805)
                     /locus_tag="KNP54_003654"
     CDS             complement(1416..1805)
                     /locus_tag="KNP54_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0894510.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
     gene            complement(3566..4972)
                     /locus_tag="KNP54_003655"
     CDS             complement(3566..4972)
                     /locus_tag="KNP54_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0894511.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQTLNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(5017..5724)
                     /locus_tag="KNP54_003656"
     CDS             complement(5017..5724)
                     /locus_tag="KNP54_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894512.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            5895..6809
                     /locus_tag="KNP54_003657"
     CDS             5895..6809
                     /locus_tag="KNP54_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894513.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            6809..7570
                     /locus_tag="KNP54_003658"
     CDS             6809..7570
                     /locus_tag="KNP54_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894514.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            7582..8319
                     /locus_tag="KNP54_003659"
     CDS             7582..8319
                     /locus_tag="KNP54_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894515.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            9197..9466
                     /locus_tag="KNP54_003660"
     CDS             9197..9466
                     /locus_tag="KNP54_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBF0894516.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(9684..9929)
                     /locus_tag="KNP54_003661"
     CDS             complement(9684..9929)
                     /locus_tag="KNP54_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBF0894517.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
BASE COUNT         3394 a         1563 c         1089 g         4030 t
ORIGIN      
        1 aatactagtc ctatatatta tcttgaatta gttctattac aattaatttc tactaaataa
       61 ttataattta aacaatcatt ccttactatt ttcacactgc tttacaaatt taattggatg
      121 ttgaattatt ttagaagttt cttctacaga gtatccctca gataaatatc ttctagctat
      181 aacttccata gactctccta tctcaataat atgcttatcc gggtcataaa tacgcactac
      241 tctttgttgc cattcatgtt ttagtggctt atggacaaac tctacatctt tataataatt
      301 gagtttttca ataaattcgt caaaatcatc aacctcaaaa taaagttcca tattatttga
      361 tttttgtata attgtatctg gattaatccc tgtaagccat gcgaagtctt cttgtatagc
      421 aaatcctcct ttaaatgtta catttttgcc taagtccaat tcaatttctt gctcaaataa
      481 ttctttataa aatttttttg atacttcaat atccttcact gctaataatg aaacctgata
      541 tttcataaat tttcctccta attttttatt tctatttttt cagtatcttc tattaacatt
      601 tttttctcta tctcttcagt accttttatt aatcctttat ttttactttt ttagcatctt
      661 ctattaacac ttttgtttct acctattcag tatcttatat caatctttta ttttttcaat
      721 atcttctatt aacactttta tctctatcta ttcagtactt tctatcaatc ttttgttttt
      781 atgttttcaa tatcttctat taacactttt gtttctacct cttcagtatc ttatatcaat
      841 cttttatttt ttcaatatct tctattaaca cttttatctc tatctattca gtactttcta
      901 tcaatctttt gtttttattt tttcaatatc ttctattaat acttttgttt ctacctcttc
      961 agtatcttat atcaatcttt tattttttca atatcttctg ttaacacttt tatctctatc
     1021 tctttaatat cttatattaa tcctttattt ttattttttc aatatcatca ttaattccta
     1081 tttattttat catcttaaat acgaaaacac tgtgtcatat ttgcaaaata tatattatca
     1141 tctatattaa agcttcacaa tttatattta aaaattctct ttaattacac tacctctatt
     1201 taaaaagcta ccttaattat acttataagt aaaggtagct ttttaaattt aattaaatag
     1261 aatatccact attaatttat atttaattta tttagattca cattatagta tcataatcca
     1321 cttataatca tttgtcatat tacttaagta gactaatata ttacataaat acacttacat
     1381 acactttata ttgatgctat aagaaatacg tttgcttata cgtctttctc ctcttctttt
     1441 agatttttta tccactcttc aataagtaaa atatcatctt tgctcaaatt aatattttca
     1501 tgtaatgaca acaataaact ttttatagaa gaatcatgaa tatttctaaa aaaatctctt
     1561 gtctcaactc ctatgtattc cttttcttta attaaaactt cataatgcgt atatttatct
     1621 atcttttgag aatttagaaa tctttttact actaatctag ataaaagagt caaagttgtc
     1681 gtttgtttcc attgatattt ttgctccatt cctaaaacaa tatctctaga tgttactttg
     1741 gaatctgatt tccatataaa tttcattatc tttaattctg attgtggcaa cttttttata
     1801 gtcatgataa aaccttgcta ctcagaatat agacaagcaa tatccataat aaaatttttc
     1861 gattaaatac atcttatacg gatttatata agctcagact tataagatat ttttcaatct
     1921 taatcctaaa tttagctatt tgtacacggt aaatatatat aaataatgtc aaaattctct
     1981 tgtattatat tgcttaattt tatgaaatat tttgtactca gctatctatt ttggatactt
     2041 gtccagtagc tctcctttct tttaaactct ttgattttaa atatttgtat ttcagtaaat
     2101 cctacttcct aaatttttta tttactacaa cttattactg aacttcctac ttcctaaact
     2161 ttttatttac tacaacttat tactgaactt ctcacttact aaatttctta cttactataa
     2221 attataacta aacttctcac ttactaaatt tcttacttac tataaattac tactaaactt
     2281 cctactttct aaatttctta cttgctacaa attattacta aacttcctct ccctaaattt
     2341 cttacttgct ataaattatt actaaacttc ctactttcta aatttcttac ttactataaa
     2401 ttattactaa acttcctact ccctaatttt cttacttact ataaattatt actaaatttc
     2461 ctactttcta aatttcttac ttactacaaa ttattactaa acttcctact ccctaaattt
     2521 cttacttgct ataaattatt actaaacttc ctactcccta agtttcttac ttgctacaaa
     2581 ttattactaa acttcctact tcctaaattt cttacttgct ataaattatt actactaaac
     2641 ttcccacttc ctaaatttct tacttactac tacttataac taaacttccc acttcctaaa
     2701 tttcttactt actaccactt ataactaaac ttcccacttc ctaaatttct tacttactac
     2761 cacttataac taaacttccc acttcctaaa tttcttactt actaccactt atcactaaac
     2821 ttcctacttt ctaaatttct tgcttcttaa gaataatgtt aattttaatt ttaagattat
     2881 agtttttacc ttgtttaatt gaaacattct atataattat atccttctat tttagagttt
     2941 ttttatttat atattacaaa gtttaaattt tttcattaat tatattataa attttccata
     3001 tatttcaaca taaatacata tatatatatg ttatttctaa aaatactaca caaaaactct
     3061 actttagtag aactcaatgg cgcaaaatac ttcaatttaa aacatttatc gtactttaaa
     3121 taaataacta taataaaata tacttacaat agttacatag aagctattat aactacacag
     3181 aacagcttat aattaaaact tttttaggat gtcattatat tttttcttaa aattaaaaaa
     3241 cactatacca taattctatt ttagtagaat ttttttgtca ataataaaat taaatattaa
     3301 ctaaaaaata aaaaaaatgg aattatctaa agaatttaat aaccttacaa taattccaaa
     3361 atattatttc tatgaaaatt ttgataccat gagtaactca gccataagcg cataaagcac
     3421 aagttactct ttactttaat aaaacttgac aagaaaagaa tttatcctta ttctactcta
     3481 atagagttaa tttgtcaata aagaataaaa ttattttcaa aatattttca ttcttcattc
     3541 ttatctgtta ttattttata aaatatcact taattagagg taattttagt attgttttta
     3601 gtccctgact atcaatgctc gtaatatcta atttacctct atgtgcatta ataatgccag
     3661 atactatcaa aatacctaga ccatgatttt gacctttggc atatgcctca cttagtccat
     3721 tttggctctt taataaacta ttaattcttt cttgactcat accttttcca tcatcttcaa
     3781 caattatata gcaaaaatct aaatcagact tagaggtaac ccttatatta catccttgtt
     3841 ggttatgagt tatactattt tgtattaaat tactaatagc cctttttaat aattttttat
     3901 ctgcatctat aataatatct tcatttagta tatcaagttc aacgtaaaag tcattatcca
     3961 aattattatt tataaactca gaaataagct ctctcaaaaa cgcagaaact ctaatcttat
     4021 cacaattcaa tgtttgcata ttatattcaa gtttagacac taaatttagg tcatttacta
     4081 attctctgat tttaatccct tgattgcata taatagacac ttgctcttgt tctctatttg
     4141 aaaggctact gctttcttca agttctccag catatccaat tatcattgaa agtggagttc
     4201 ttatatcatg agatattcct gcaatccagt tagacctagc ttcctctttc ttcctaagtt
     4261 tttcatcttt catttgcaac tctttagata cagtattaat agattttgaa atatcactta
     4321 gtattccttt ttcttgtaaa agtactggtt ctccttttga cataagcttt atgccagtaa
     4381 taattggttt tatagatttc accattttta aacctatgaa tagagctatt aaaaaagtaa
     4441 ctattgcatt aaccagaaac atacctatta ttaacatagg aaattgttct atttccttaa
     4501 ccgtataagt aaggttaaac ttagtatact tgtcttttgg ataacctgtt actaatattc
     4561 catttggatg ttcccataca tacacaggat agtcctttaa aaagaacctt gaaaactttg
     4621 ctacatctgt caaagtataa tgacttggaa tttcttttgg taaatcaaat ccccatattc
     4681 tatctccatt gttatcaatt aacattgccc aaactttatt tttatgtagt acttccttac
     4741 tagaatcatc taaaataaac tttccatctc ttaaaatcaa attatcttca atcataatca
     4801 agtttgattt tatttctcta ctatcacttg tatctaaatt atcagagtat ttagatacaa
     4861 ataacatata tgaaaacaga agaaaacctg ctatatttaa tacaataaaa agtaatgaaa
     4921 tcaagatact tgaacctata aatcgcctca atatgtactt tacactatcc aaaattaaat
     4981 cactcctctt gatttctttt attctaatat ctaaaattaa ttaatcatca acttatatcc
     5041 aagacctctt actgtaataa gatgtttagg tgtagatgga gttttttcta tcttctctct
     5101 aacccttcta acatgaacca taagggtatt ttcatatcca tacatatcat ctccccaaat
     5161 ggcttgacat agtgaatcat tagtaacaat tctcccttta ttttcataca actttaaaag
     5221 caacgaatgc tctttagctg ttaaagaaat ctcttgccca tctttctcaa cacatgcact
     5281 atttaaattc acaacaacag aatctcccag tttaaatact ggcaactcct cttcttctat
     5341 aggcacatat acacgattta atatacccac aagccttaaa gtaagttcct ttggtaaaaa
     5401 tggctttact atataatcgt cagcccctaa gcccaaacca atcaatctat cttcatcttc
     5461 acctcttgca gagagaaaaa tcactggtat tttagatgtc tctctaattt ttctcataat
     5521 agaaaaacca tctccatctg gcaatacaac atctaaaatt gcacaatctg gctttacatt
     5581 tctaaatacc ctaacagctt cctcataact tgatgctaaa aatactctac taaatccctc
     5641 ttttctcagg atttcatcta tcatttttaa taattccttg tggtcatcaa ccacaagtat
     5701 ttttttatct tttattgact ccataatcat caccctcctt tagtatacca tatacccatt
     5761 ttcacaactt tgcctaaata gacttttaag gttattgtaa ggtaaatttc agctaattga
     5821 aatgtaacca agttattata ctgatataag ttaaaagaat caataagcac agattaaaaa
     5881 aggggatgaa acatatggaa atgataatta gaacacaaag actttcaaag gaatacaata
     5941 aaatatttag agtaaaggat atagacctaa gagttccaca aggagctgta tatggttttt
     6001 tgggtcctaa tggagctgga aaatctacca ctcttaaaat gcttcttgga cttgctaaac
     6061 ccacacaagg aaatattaat attttaggta aagagttaaa tgaaaaaaat agaatatcaa
     6121 ttttaaaaga tataggttct ttgatagaat ctccatcata ctatggtcat cttacagggc
     6181 ttgaaaacat gaccataatg caaagactct tagatttacc taaaaaaaat gtaaatgaag
     6241 cattaaaaat tgtaaggtta gaaaatcaaa aaaataaaaa agttagtcaa tattctttag
     6301 gtatgaagca acgtcttggc attgctatgg caataatgaa gtttcccaaa ttattaatac
     6361 ttgatgaacc tacaaatgga ctcgacccag cagggattga ggaaattaga gaattaataa
     6421 aatctctacc agaaaaatac gggatgactg ttctaatctc tagccatctt ttaagtgaaa
     6481 ttgaccaaat tgccacatca ataggaataa taaatcatgg cgaactggtt tttcaagata
     6541 gcataaaaga acttcataat agaggtcaaa gtcagattgc tatcaaaact aagaatgttg
     6601 tatctgcaca aaaactatta aatactaaag gatatatgtc acttatacaa gatgggtact
     6661 tgactattga aaatttaaaa gactcagatg tcgctaaaat aaatggtatg cttgtccatt
     6721 caaatataga tgtatttaga atagaagaac ataaaaaaag cttggaagat atattcttag
     6781 aacttactgg taaggcggtg actttataat gaaatacctt ggtctagaat tttataaact
     6841 taaaagaaag aagattattc tgatgacctt tttatttgca gctgttgaaa taatgtggtg
     6901 tatcgtaaat tcaaatagag ctattacacg taatccagat atgttaggtg gatttgaata
     6961 ttcctatatg cttatgagtt ttgcaagttt aaatggtcta ttctttccta tcttaatatc
     7021 aataattaca tcacgtataa gcgatataga acataaagga gatacatgga agcttttaaa
     7081 atcttctgtg acatctttaa atagtattta tttatctaaa tttttatgtt ctgctatttt
     7141 ggtatctata cctgtattga tgcaagtgtt atctattgtg ttgtttggac attttagagg
     7201 ggttattgag tcaatttctg tatctttact tttaaaatac acattaggaa caattcttgt
     7261 aagtattgct atcattgcac tacacctatg gattgcaact gtaattccaa atcaaatgat
     7321 tgcaattaca tttggcatga ttggtagttt tataggtttg acatcaggtt tgttttatca
     7381 aggtattcgt agattgttta tatggtctta ttacctagag ttatcacctt taagttatgc
     7441 ttatgataat gttttaggtt catctgtcta tagaattgat atgaattttt ctattacgat
     7501 tttagttttc ttaattggaa tgctaattta ttatattgga agaaatcatt tattaaaaaa
     7561 agaagtatag gagggattta aatgttaagg aagtcagttt tgggagaaat tctaaagtta
     7621 aaaaattctt ttatatggta tgtattatta gctttgccac ttataagtgt gttgattggt
     7681 tctggtaatt tttatctaaa tcaaggcata ctcaaaaaag aatggtacag cttatggact
     7741 caagttagtc ttttttatgg ggaatttttc tttcctatct taatcgcaat cttttgtgca
     7801 tatatttgta ggcttgaaca tatgaatcat aattggaata atgtaatgac actgccagtt
     7861 aatttaaaaa atatcttttt atctaaactt acagtagttt caatacttac agctattaca
     7921 caagttttct ttgttatctt ttatatagtt gcaggaaata tgtttggttt ttctggtagt
     7981 gtacctaaag aattgactgg ttggattgct aaaggttgga ttatttctat ttcaatagct
     8041 tctatacaat tatacatgtc tataaagatt agaagttttg caactcctat tggtattagt
     8101 ctttgccttt ctctatttgg tatgggatta atagtagcaa aacctgctgt tggtatattt
     8161 ttcccttatt ctatgttagg tagtgctatg ggggttataa agcaatctgc tttaaatgtt
     8221 aatgacacta tagttacaat atgtgttgca tttattacta ctatagtatt ttctgaaatt
     8281 gccaatagaa attttagaaa gaatgatgtt atttcttaat ggtaaatgct agatattttt
     8341 gggtttgaaa tttatattct ttttagttga aatctatatc cattttattt aaaaatatat
     8401 atcttttatt tgaattttat atgttttatc tactcgctat ataatagata tactcctaaa
     8461 atttaaaaat atataataat gttattattt aaaattatta tgtattatat taaaacttaa
     8521 tgcaaaaaca atttttatat tatataatga aacttaatta aatataggta aaaaatcatt
     8581 caatatatta aataaatatt taactttaat aatctatatt taattatagc tataacatag
     8641 aattatcaaa tatattgaat gaatatttga ctcttggaat gtgtaattaa attaagtttg
     8701 gttattcgat ggaaggcaaa tttgatataa aactccattt aaagtgccag ataaaaactt
     8761 tatggttata taaaagttaa aagtaattta tagtgttata gaacattcaa agggatttaa
     8821 agtaatctat ggtgttttga aatattcaaa gggatttaaa ctaatctata gtcttgtaga
     8881 atattcaaag agatttaaaa caatctataa tgttgtaaaa tatattcaaa gggatttaaa
     8941 ctaatctata gtcttgtaga atattcaaag agatttaaag caatctataa tgctgtaaaa
     9001 tatattcaag gggatttgaa gtaatttatt gtgttttgaa atattcaaaa agatttttgg
     9061 aatagttttt ataaatttac cagtactaat aattttatgt ttaacattta gatgacctaa
     9121 aatcaactat ttgcactttt gtattcatct aaaatcattt tataatattt ttaaataatg
     9181 gaaaggatgt ttgaatatgt ttgaatcaag atgtggtgtc tgttgtgaca gttgtacaaa
     9241 aaaagaacaa gtaaattgca ctggttgccc aactatggaa aaaccatttt ggggtggaga
     9301 atgtaaggtt aaaacttgct gtgaaagtaa ggaacttaat cattgtggtg aatgtgatac
     9361 tttcccttgt gatatgcttt taaataaggg aaaagaccaa ggttttgacc ctatggtaaa
     9421 tattgagcaa tgtagaaaat ggcttgaaga aacagtttct aattaattgt tttagaatgc
     9481 tttgttaagg aatttattta atcctttgtt aggtagtatg tttagtcatt tgttgattag
     9541 tatatttata catttattga tgggtatatt tagccataca aatagattta cataaaattt
     9601 acgactaaaa aagagttgag tattagtttt tattatttaa aacggatatt caactctttt
     9661 ttatgtctaa cttttttgat tttttaatct ttccaatacc accactttaa tttttctggt
     9721 tctggatttt cagttgatgc aaaatatact gcacatctgt atacatataa ctgacatctg
     9781 tctatgtgct gtccacgcat taaacattcc ttttcataca tttgtgctgg gtttgcatct
     9841 ttaagtgatt taatagttgt atatcctaac atgattaaag atttttctgt tgctttccct
     9901 acccctggaa ttttttgtag ttctcccata cttcaccttc tttctggtat attcttttta
     9961 tattatacct attaccagat atttttttat tatagttaat atttaatatt taatttttta
    10021 ttatatcaat ttatttatgc tctttcatat atatatattt taccacctct aaatca
//
LOCUS       DAEHWO010000121         9596 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEHWO010000121 DAEHWO010000000
VERSION     DAEHWO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9596
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.124"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            60..794
                     /locus_tag="KNP54_003662"
     CDS             60..794
                     /locus_tag="KNP54_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894518.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            1005..2186
                     /locus_tag="KNP54_003663"
     CDS             1005..2186
                     /locus_tag="KNP54_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBF0894519.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVISDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            2170..2742
                     /gene="mobB"
                     /locus_tag="KNP54_003664"
     CDS             2170..2742
                     /gene="mobB"
                     /locus_tag="KNP54_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBF0894520.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            2861..3136
                     /locus_tag="KNP54_003665"
     CDS             2861..3136
                     /locus_tag="KNP54_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0894521.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            3379..5079
                     /locus_tag="KNP54_003666"
     CDS             3379..5079
                     /locus_tag="KNP54_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894522.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            5442..6629
                     /locus_tag="KNP54_003667"
     CDS             5442..6629
                     /locus_tag="KNP54_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894523.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            6689..7852
                     /locus_tag="KNP54_003668"
     CDS             6689..7852
                     /locus_tag="KNP54_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBF0894524.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGDNPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            8003..8806
                     /gene="zupT"
                     /locus_tag="KNP54_003669"
     CDS             8003..8806
                     /gene="zupT"
                     /locus_tag="KNP54_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBF0894525.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            8901..9461
                     /locus_tag="KNP54_003670"
     CDS             8901..9461
                     /locus_tag="KNP54_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBF0894526.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
BASE COUNT         3733 a          953 c         1756 g         3154 t
ORIGIN      
        1 ataactgtaa attgagatat agataaatac tataaaattt aagaaaggag gattgattta
       61 tgaagttaaa aaggtcatta gtttgtgtaa ctattttagg tattatactt gttggatgtc
      121 ataaagaaaa tactaaagag aaaaatcaag tagcaagtaa agcaacacag caaaaaacta
      181 tgacaaaagt tcaaaatgat gttaatgaaa ttatgaataa agattataag tacattataa
      241 agaatatggg tataccttat aatacatttt attatataaa acctaaagtt ttaaaagaat
      301 caaatacaat gcaagatata aatacatcaa gttatatgac attagtttat ccaaaatata
      361 ctggaaatga tgaactagat ggaagtgctt tatatgttga tattaacgaa aataaagttg
      421 tcaatgttga aaccaattct ttctcatcac aaggtatatc agtcattgat gctgaatcta
      481 gtatagtgat tgaaaaaagt gaccatgaaa aatcggctgt atcactagaa aattttagac
      541 atattgacct gggagagtat gttggtgttg aagattccag aataaatgaa attgtaggag
      601 atgcgaatta tgatttaaca gcatataatc atgaaggcag taaagtagtt aagagttata
      661 gattgaaaga agataacaaa atattaaaaa aagaggtact tacaataagt attgtggata
      721 acaaaataaa atctataaaa actattgaaa gtgataaaat tgtaaaaata ataaaaggaa
      781 ctttattaga ataaaatatt ctaaagcata tgatgctgtt tcaagataga aggaaatttc
      841 tagctgggaa cagttttttt attagattta taaaatttga actgcactta tagataacta
      901 ttagttataa ttaaatataa gataaaagta tttccaactt ttataatcta taatatatta
      961 catagaaata tcttaaataa aaaatatatt ggggagtatt taaaatgata gaattagaag
     1021 atgccataaa aattattgaa aaaaatgttt taccaataaa cagggtcaag atagtaaatc
     1081 ttatagatgc agtaaataag gtagttgcag aagatatata ttcaacaatt gatagtcctc
     1141 catttgatag gtcaccctat gatggttatg catataatgc aaattctgaa aatagaaatt
     1201 taaaggttat agggactttg tatgcaggag atgtatttaa tagggtatta aataaaaatg
     1261 aagcagtgaa gataatgact ggtggaaaga taccacaggg tgcaaattgt gtaataaaaa
     1321 aagaagatgt aacagttata agtgatatga taactttaaa tataaaatta aaggaatacg
     1381 ataattacat atttaagggt gaggatataa aaaaggggca attgattatt aataaaaatc
     1441 agaatatagg atatgatggt attggagtat tagcaagtct tggaatatcc aaagtaactg
     1501 tttatgatga tttaaaagtt ggaattttga atacaggtac agaactacaa gatataaatg
     1561 agactttaga gaatggtaaa atatacgata gtaatagata taccttatat tcaagattat
     1621 taaaacttgg aatacaagca gatacaatat gcaattgttc tgatgatata ttggagttag
     1681 aaaaaaaggt aaagaatatg ttacagagtg tagatttttt aattaccaca ggtggtgttt
     1741 ctgttggaga taaagattta attccagatg tattcaaaaa aataggggca acagaattat
     1801 tttggaagat aaacattaaa cctggtggag cttgttatgt aggtacattg ggagaaaagc
     1861 tattatttgg tctttctggt aatccacatg cagcaatagt ggtatttgat aatgtgatag
     1921 ttcctgttat tgagtattta acatataaga agggaacaca tcatataaaa gctatattta
     1981 aaggagaatt taataaactt tcaaataaag atagatttgt aagtggaaaa ctatatacaa
     2041 gtgaaggtaa attgtatgta gagctaaatg ataagaaaga tgcaaaagct agattatctg
     2101 caactctaag aagtaattgt atgattaaga ttaaaaagaa tgagacaata aaagaaaatc
     2161 aattagtgga tgttgttatt agatagtttt atgaaaggac acaattttat gtataatata
     2221 ttgtcagttg tctcatattc aggagtaggt aaaactacat tgattgaagg cataataaaa
     2281 gaattaaata aaaaagggta tcgtgttgga gttattaaac atacctgtca tgattttgat
     2341 atggatgagg aaggaaaaga tacttataaa catagaaaat ctggggcgag aaaagtctgt
     2401 ataatatcag ataaacgagt agcatatatt gaagaactaa aagagaagaa tccattatat
     2461 aaaatgattc aattatatga agatatggac ttgattatca tagaaggata taaaaattat
     2521 agatttaaaa gattggaagt aactagaaaa ggtaagtatg aggatatttt atctaataag
     2581 tctgatttga taggtattgt cagtgatata gaatataaat tgaatattga acagtttaat
     2641 ttaaatgatt ataaaaatat atcaaagtac atagagtctt gtataaaaaa tgaaatttta
     2701 agtataagca atgttgaaat aaaaaacata ttaaaagaat aattttaaga tgttcttctt
     2761 atataaaatg atataattat ttatataaat aaagatataa gaaatttatc aattttattt
     2821 tgagttataa aatattaaag aaattgtagg aggacaatat atgaaaaaaa tattagtagc
     2881 ctgtggagca ggaatcgcaa catcaacaat agtttgtgac agagtagaaa gattggttaa
     2941 agaaaataat atacaagcag aagttgagca atgtaaaatt gctgaatgtt caacaaaaca
     3001 agaaggtgct gatttaatcg tatctactac tatactacca acaacttatg atatacctac
     3061 aataaaggca acaggatata taacaggtat aaatacaaca gcattagata aaaagatatt
     3121 aaatgcattg aagtagtttt gtatttataa aaaaaattta gtattaaata tagagttgta
     3181 tctttataaa attttaaata tagagatata gctcttttta tgttgtttca agtatacaac
     3241 tatatgatat aaatcttcaa ttttatgaaa aagattgtta ttactttgta agtttataaa
     3301 agatttaaag ttattgttat gttatactaa tttatgggta ttttttagaa gtactaataa
     3361 aggagggatt taatacttat gataaaacaa tttgtcaaat attataagcc atataagaaa
     3421 atttttacac tagaccttat agcagctttt ctattttcct tatgtgattt agtttatcct
     3481 atgataacta gaaatataat ggatgacgtt gttccaaata aaaacttaag aatgttagta
     3541 gtttttgcag tagcacttat acttatattt atagcaaaag cagggcttaa ctattttatg
     3601 cagtattggg gacatgttat tggtgtagat atgcaagctg atatgagaaa tgaggtattt
     3661 acacacttac aaagacttcc aaatacgtat tttgataata acaaatctgg agtaactatg
     3721 tctagaatag taaatgattt aatggatata acagaacttg cacatcatgg gcctgaagat
     3781 ttattcattt ctatagtaat gttggttggt tcattcttta tacttataga tataaatatt
     3841 cctcttacgc ttataatatt tgctatatta ccgtttataa tttggtttgc aatagctaaa
     3901 aaagataaga tgaatattgc ttttatgaag agtagagtta ctataggtga tgtaaatgct
     3961 actttagaaa atagtatagc aggtatgaag gtaactaagt ctttttgtac tgagaaagaa
     4021 gagttaaata agtttgtaag aagcaataaa ttatttagaa gagcaagaca agattcttat
     4081 aaggtaatgg cagaatatta ctctggtatg aatttataca tggatatctt agagtgggta
     4141 gttgtaatag ctggtggtta ttttacttat ataggaaaga ttactttggg tgattttgct
     4201 gcttatatac tatatgtaaa aatgtttata caacctatga aaaaattaat aaactttaca
     4261 gagcaatatc aaaatggtat gacaggtttt aaaagattca tagagataat ggaacaagac
     4321 catcaaaaag aagctaaaaa tcctattgaa cttgaaaatg taaaaggtga cattgagata
     4381 gaaaatatat ctttcacata tgaagataag actcaagttt tggataattt aagtttatct
     4441 ataaaagctg gtaagactat agcattagtt ggaccttctg gaggaggaaa gactacatta
     4501 tgtaatctat tgccaagatt ttatgaattt gataagggtg atataaaaat tgatggaaag
     4561 agtataaaag atgttagttt aaaatcattg agaaaaaata taggtatagt tcaacaagat
     4621 gtatttttat ttacaggaac tataagagat aatattcttt gtgggaaccc taatgctaca
     4681 gatgaagaaa tgatagctgc tgctaaaaaa gctagaatac atgactttgt agagactttg
     4741 ccagatggat atgatactta tataggagaa agaggcgtaa aattatcagg tgggcaaaaa
     4801 caaagaattt caatttcaag aatcttttta aagaatcctc caataataat attggatgag
     4861 gctacatctg ctttagacaa tgtaacagaa agagaaattc aagagtcttt agaggaatta
     4921 agtaaagata gaacaaattt agttgttgca catagattga ctactataaa aaatgctgat
     4981 gaaatcatag tattgacgga taaaggaatt gaagaaagag gtactcatga agagctagta
     5041 aacaaaaatg gagtatatag taggttacac aataactagt atacaaattt tacaccatag
     5101 ctaacataca cattaaactt acaaacatag gatatattaa gattcataaa gacaattcat
     5161 tttatattta taagatgttt tatgaataaa atgtatccta tgttttattt tttgcaaatt
     5221 acatttaatt ctctttgtaa gaatagagtt aaatagccaa tggtcgggat aacgttttta
     5281 caaaaagaat aatttagaaa actaacttta atttatggaa tttatcgaat tttatgaaaa
     5341 aaatcgaatt ttgacttgaa atgtttttca aaagtagtaa aataatggat aactatacat
     5401 acattttata aaaatatatt tattatgagg ggggattttg tatggaggca ataacagctt
     5461 tttgtctagt tttagtatca ctgacgatag gagatatagt ttcagcaaaa actaaagctt
     5521 ttgttccgtc ggtttttgta tcagcaatta tatttatagt aggattttgg acttttttcc
     5581 cagaaaatat tgtggactta gccgctttag gaacaccatt agctcaatta ggtatgcttt
     5641 tgttaataac tcatatggga actatgatga gtattaagga attagcaggt caatggaaaa
     5701 caatagtaat agccttggca ggaatagtag gaatatgtgt aggtgctttg gcattaggga
     5761 cagtagtatt tggatgggat acagcagtaa tagctacacc tcctcttact ggagggctag
     5821 ttgcatctat aatgatggca gatgctgcta cagcaaaagg tcttgcaagt ttatcagtac
     5881 ttgcaatttt gatgtatgtt gcacaaggat ttgcgggtta tcctattaca gcattaatgc
     5941 ttaaaaaaga aggaaaaaga cttttatcag actttagaag tggaaaagta actgtaaata
     6001 cagatgaaga aaaagttaag gatttacctg aacaaaaaag cagatttaag ataataccag
     6061 acttaccaga aaaatatgat acgacatata tgataatact tagattagga tttgtagcat
     6121 ggttagcagt acaatttaca aatcttacaa atgaagttgt atcaagatat gttatatgtt
     6181 taatatttgg tgtaatagca tcagaacttg gaatagttga tagaaaacca cttaataaat
     6241 ctggttcatt tggatggtta atgacatcat tgatggcttt tatatttgca gggttagcaa
     6301 aagctacacc agcaatgctt gttgaaatgg cagttcctct tgtaggaatc ataatatttg
     6361 gtgtaatagg tatgggaatt ttctctatta tagtaggtaa gcttttaggt gaaagtaaag
     6421 aaatggcttt ttcagtttcg cttacatcac tttatggttt tccaccaaac tatatattaa
     6481 ctgaagaggc agtaaaggct ttggctgaaa caccagaaga aaaagaattt ttaatggata
     6541 aaatgcttcc aaagatgctt gttggaggat ttactacagt tacaatagct tctgtagtaa
     6601 tagcaggtat ctttgtaaat ctaatatagt atttaattga taaaaagtat tttaaataag
     6661 aagaatgtgt actacttgga ggtatagaat ggatattaaa gaaataacaa agagttataa
     6721 agactatgta attaagctta gaagggaatt tcatgaaaat cctgagaaaa gtatggaaga
     6781 agttagaaca tcaaagagag ttaaagaaga acttgataaa atagggatac catatgtatc
     6841 agctggaggt acaggtgtaa ttgcaactat aaaaggagat aatccaggaa agactgtagc
     6901 acttaggggt gatatggatg ctctacaagt tgttgaatgc actgatgtag aatacaaatc
     6961 taaaaatgaa ggacttatgc atgcttgtgg tcatgatggt cacacatcaa tgcttctagg
     7021 ggcagcaaaa gtgttaaatg atattaagga tagtatcaat ggaactgtaa aattattttt
     7081 tcagccagga gaagaagttg gtaaaggtgc aagagctatg attcaagatg gtgctatgga
     7141 aggtgtagat agtgtgtttg gaatacatct ttggactgat gtagaatctg ggaccatatc
     7201 ggtagaagaa ggaccaagaa tggcttctgc tgatttcttt aaaattactg taaaaggtag
     7261 aggtggtcat ggttcacttc ctcatcaagg tgttgatgca gtgcttgcaa gttcagcaat
     7321 agttatgaat ctacaatcta tggttagtag agaagtaagt cctctggaac cattagttgt
     7381 gagtgttgga gttttaaatt ctggaactag atttaatgta attgcgagtg aagctatctt
     7441 agaaggtaca ataaggctat ttaatccaga gcttagaaag caaattcctg gaattttaga
     7501 acgtatagca aaatctacag cagaagcata tagagcagat gctgaattag agtatgggta
     7561 cttaacacca gcagttataa atgacaaaga atgttcaaag atagctacag atgcagcaat
     7621 taagctattt ggagaagact gtataacact atttgaaaaa gtaacaggag cagaagattt
     7681 agctgagttt atgaatatag cacctggtgc actagcattt gtaggagcta gaaatgagtc
     7741 aaaaggtgct tgttatcctc atcatcatgg atgctttaat atagatgaag atgctctaga
     7801 aattggaact gctttatatg tgcaatatgc agtggatttc ttaaataaat aattttaata
     7861 tactataaag aaaaagcaga gactaagttt atatctctgc ttttttattg tgtatatttt
     7921 ttataaatat tgactatata aaatatatat gatagcataa agaaaatgat aatcaatatc
     7981 aattaaaaag aaggtgattt atttgaataa tgtaatattt gcatttttga taacattatt
     8041 ggctggttta tctactggta taggaagttg tatagcattt tttgctaaaa aaacaaatac
     8101 taagtttctt tctataagct taggattttc tgctggtgtt atgatttatg tttctatgat
     8161 agaaattttt cctaaagcac aagatgcttt gacaaaatct atgggagaga aattaggaag
     8221 ttggtcaact gtaatagctt tttttatagg tatggctatc attgctgtta ttgataagct
     8281 aattccacaa gaagaaaatc cacatgaaat aaagaaaatg gagaatatag aagaaaagaa
     8341 tatcaaaaaa aataagtctc ttttaagaac aggtatattt acagcaatgg ctatagcaat
     8401 tcacaatttt cctgaaggat tagctacatt tatatcagct cttgatgatg ttacaatagc
     8461 tattccgata gcaattgcaa ttgcaataca caatatacca gaaggtatat ctgtatctgt
     8521 accagtttat tatgccacag gagataaaaa gaaagctttt tattattcct ttttatctgg
     8581 tatgtctgag cctttaggag cgattattgg atatgtactt cttagaaatt ttttaaatga
     8641 tataactctt ggaattgtat ttgcaattgt aggaggaatt atggtattca tatcactaga
     8701 tgaattattg ccatcagcta gagagtacgg ggaacatcat ttatctattt atggattgat
     8761 tgcaggaatg ggtgttatgg ctattagttt attactattt aaataacttt taaatatatg
     8821 attgtaacct aaaattagta tcaaaatgat ataattattt aaatagattt ttaagctatt
     8881 taaaaatatc attttggaga atgagtgcta tggaaaagaa aataaaattc aaatttgact
     8941 ggtatagttc acctgataag atagagaaat ggttagaaga tattgaagct aaaggatata
     9001 atttatataa gataaataaa tttggaggaa tattttattt tcataaggga agtccaagaa
     9061 aaataaaata cactgttgat tactactatg atgtagagaa taattatttt gatgaacata
     9121 aatcaaatgg ctggaatctt gtatttagga gtattggtag ttttatgggt acatctgcat
     9181 ggtatatatg gtcgaaagaa tacaaagaca tacctcctaa attatatagt gattctgata
     9241 aaacaaataa agtaaagtca attttattta tgaatatgtt tatattcttt atgttagtag
     9301 taatatttat atatttattg aatattgaaa taagaaattt atatagtggt tatggagcat
     9361 ctgtaactgc tattgtacta cagattatat tgttgatttt atatgcagta caattatata
     9421 ggagattaat gtattattta aggcttaaaa agtttaaata aataaaagaa ggtgtcctaa
     9481 aattattttt ttaatatttt aagacatctt cttttgtcag taagtactgt ttttaattat
     9541 agtaatttct gtctttaaat tgaaatatca aataatagtt gtatgggatt gagtat
//
LOCUS       DAEHWO010000122         8974 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEHWO010000122 DAEHWO010000000
VERSION     DAEHWO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.125"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            176..1381
                     /locus_tag="KNP54_003671"
     CDS             176..1381
                     /locus_tag="KNP54_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBF0894527.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKG
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1452..1673)
                     /locus_tag="KNP54_003672"
     CDS             complement(1452..1673)
                     /locus_tag="KNP54_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894528.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(1814..2413)
                     /gene="recR"
                     /locus_tag="KNP54_003673"
     CDS             complement(1814..2413)
                     /gene="recR"
                     /locus_tag="KNP54_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBF0894529.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2426..2776)
                     /locus_tag="KNP54_003674"
     CDS             complement(2426..2776)
                     /locus_tag="KNP54_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBF0894530.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(2835..4472)
                     /gene="dnaX"
                     /locus_tag="KNP54_003675"
     CDS             complement(2835..4472)
                     /gene="dnaX"
                     /locus_tag="KNP54_003675"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBF0894531.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4549..4813)
                     /gene="ffs"
                     /locus_tag="KNP54_003676"
     ncRNA           complement(4549..4813)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KNP54_003676"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(4851..4942)
                     /locus_tag="KNP54_003677"
     tRNA            complement(4851..4942)
                     /locus_tag="KNP54_003677"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4906..4908),aa:Ser,seq:gga)
     gene            complement(4943..5398)
                     /locus_tag="KNP54_003678"
     CDS             complement(4943..5398)
                     /locus_tag="KNP54_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBF0894532.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5719..6990)
                     /gene="serS"
                     /locus_tag="KNP54_003679"
     CDS             complement(5719..6990)
                     /gene="serS"
                     /locus_tag="KNP54_003679"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBF0894533.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7116..7321)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7449..8330)
                     /locus_tag="KNP54_003680"
     CDS             complement(7449..8330)
                     /locus_tag="KNP54_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBF0894534.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8342..8851)
                     /locus_tag="KNP54_003681"
     CDS             complement(8342..8851)
                     /locus_tag="KNP54_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBF0894535.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2877 a         1572 c          963 g         3562 t
ORIGIN      
        1 tttttaatat aacatatttg ataaaattaa tttacatttc tttcacttgt aatttttgca
       61 atcttgtatt agattaatat taaaaataat ttatcaataa ccttattcac aaagacagtt
      121 tttatatatc aaaatataat ataaatacta tgctacattt taggaggatt ttattatgag
      181 caaaaaagta ttaataatgt ctgcttccac tggtggtggg cataataggg ctgctctagc
      241 tattaaagaa gaacttactt ccaaaacact tgatggagag ccaattgaat gtgaaataat
      301 agatagtttg aaattagtta ataatacaat ggataaaata atttcaagag gatacgaaaa
      361 atctgctata tatactccca aagcctatgg aagtgtatat agattatctg aaacaaatct
      421 tttatcaaaa aatgaattta aagataatct actaataaca ttcatggcta aaaaatttaa
      481 aaaacttatt agaagcgaaa aaccagactt gattatagga acgcatcctt ttccaatgat
      541 tgctctaagt acattgaaaa aaaactttaa tttacataat aatgaatcaa atgcttacac
      601 agagcatttt tataaacatt atacaaatac cattaatgtt cctccgctta tttctgtatt
      661 aaccgattat actactcatt ctacatggat acaaaatgaa attgattact atattgttgg
      721 tcatgaatat gtaaaagaat tattggtgtt tgatggagtt gaaccgagta aaattagaac
      781 atttggaatc cctgttgaaa aatcttttct ctctcacaga gataaaggta ttgttctttc
      841 tgagttgaat ttatctcctg ataaattaac tgttttactt atggggggta gctttggggc
      901 tggaaatata aaagagacac ttgatgaatt actggatact gatagagact ttcaaatact
      961 tgtaattact ggtaagaatg aaagcctaaa agaaaaaatc gaaaaaaaac ttatgtctcg
     1021 ttatcatgat aaaaatgtat gtgttcttgg atacactgat aagatgaatg atattttagc
     1081 ttctatagat gtattagtaa gcaaacctgg tggacttact acaactgagg ctcttttaaa
     1141 agatgtacct atgatagttc cttattatat accaggtcag gaagaagaga atcttgattt
     1201 cttatctaat tgtggtgcag cacttagaac tacaaaaaaa tataacttgt caatattact
     1261 aaaagtttta atagatgacc ctagcagatt agaaatgcta aaaagaaata ttaaatcaat
     1321 aagaaagtca aattcagccc aaaatatagc taatttaatt ttaaatataa tttctggttg
     1381 ataaaataaa taaaatccct atagtatata tattatctat tagggatttt ttattttcta
     1441 attatttaat attaaattgg ttcataaaag tcttcttcat aatcatactg ataattttta
     1501 taattatttc taaattcagc atttttattt cgtacatttt ttttagtttt tttcttatta
     1561 gaaaaactta tatcctcaaa atcatcatat ttaggtttat cttttgattt cattttttta
     1621 actctttttt ctttcattgc attatgttct tctaagttca taattggttt catgttgcac
     1681 ccctatcaaa atttttaaat gatttataca acaaattata caatacagaa gaaatttatt
     1741 caataaatct aaatcaaaat taatttgaat ttaactcaaa aaattacaaa aatcgaggta
     1801 ttaacctcga tttttatatt tctcttctgc cttctagtgc ttttgatatt gtgacctcat
     1861 ctgcatactc taaatcgcct ccaacaggaa gaccatgagc tatccgagtg actttgattc
     1921 ccattggttt tactaaccta gcaatataca tggctgtagc ttcaccttca atagtaggat
     1981 ttgttgccat tattatttct ttgacttcct gattgccaag tctttggata agttccttta
     2041 tttttaacat atctggtcca attccatcca ttggagaaat tactccattt aatacatggt
     2101 actgtccttt aaactctctc gttctctcca tagctgctac atctcttgga tcttccacaa
     2161 cacatataac acttgaatct ctacttttat ttgaacacat gctacatggg tctgtatctg
     2221 ttatattaca acaaattgag caatatctta tttctctttt tgcatctata atcgctttag
     2281 ataaagcttc cacatcatta gtattcatat taataatatg aaaagccaat ctttgagcag
     2341 tctttcttcc tactccagga agctttgaaa attcctctat aagtctcgtt atgggacctg
     2401 tataaacttg cataaatacc acctactaga ataacccagg tatattcata cctccagtta
     2461 ccttactcat ttgacttgct tgtatatcat caatatttct caatgcttga tttactgcac
     2521 ttaaaactaa atcttgtagc atttctatat catctggatc aactacttct ggcttgatag
     2581 ttatatctat aacttctttt ttaccattaa cttttacagt aactgctcct ccaccaactg
     2641 aagcttctac ttctttactt tctaactctt gttgagcttt ttgcatattt tcttgcattt
     2701 tttgagcctg ctttaacaag ttgttcatat ttccaccacc aggcatcatt ccgcctccaa
     2761 aacctttttt agccataaac actattcctc ctaaacttat tttcatttta ttattatatc
     2821 ataatagtat tttattattt actctcattt tcatcaatac tatcttttat ttctaatatc
     2881 tcttcactca ctatgttctt taatatttcc tcaccaatgt cctttttctc tttaacttca
     2941 agatttatat ctttaacttc tgatgtcagt actattttta cattaaaact tctatttaaa
     3001 acatctctta ttgttttttc taaataattt attgtatctt gagagctcag tctagttttt
     3061 gcaaaatcaa atttatcatc aaatataaca tacaacatat tagaatatac attaaaactt
     3121 tttacttcac ttaagagtgc gtatattggc atttttttat cttttttaat ttgtttaagt
     3181 atattcttcc aagatgactc tataagtata acgtcctcat tttttacatc ttcataaact
     3241 acattttctt gttttacatc tatttctcta tcgacctcat actctttttc tttattattc
     3301 ccaatttttt cagacttaaa gttccccagt tcaatcattt tttctaagtt ctcaactctt
     3361 tttataagag cttctttact ttcatcaaac attggttgag caattttcat tatggttatt
     3421 tccactaaaa cccttggatt tgaagatgac tttatatcat cctgagttat tgataatata
     3481 tttaaaatcc ttattaaatc atttatatct atatttttag actgaatttt aagttgttct
     3541 atagtttctt ctggtaatga aattatttca tccaattctg atgaaacctt acataccatt
     3601 aaatttctaa aatgatcaat taagtcattt ataagatttc ttatatcttt gccccataag
     3661 acaaattcat ttaatatctc aagagacttt ttagtgtcct gctctactat acattgagac
     3721 aattcaaata attgttctat atttacgctt cccattaatt caacaacatc tttataatct
     3781 atcttacttt ctccaaaaga catacattgg tctaatatac taagtgcatc tctaagagct
     3841 ccttgagaat ttctagctat taaattaaga gctttatcat ctatatcaat tccttcatct
     3901 tcacaaatct ttttcattct aagggtcata tctttaactg taactctttt aaaatcgtat
     3961 ctttggcatc ttgataaaat ggttgcaggt attttgtgag gctctgtagt tgctaatata
     4021 aaaattacat atgatggagg ttcctctaag gtctttaata atgcattaaa agctccttga
     4081 gacaacatat gaacttcatc tattatatat actttatatt tagcattggc tggagaatat
     4141 ttcacacttt ctctaagctc tcttatatca tctacactat tatttgaagc tgcatctatt
     4201 tctacaacat ccattgtatt atcttttaat acagattcgc atatctcaca ctcattacac
     4261 ggttcttcat ttattttatt caaacagttt actgctcttg aaaaaatctt tgcagtagat
     4321 gttttaccag tacctcttgt tccacaaaac aaataagcat gtcctatatt atcactatat
     4381 atttgattct ttaaagtctt aataatatga tcttgaccaa taacatcttc aaatttttgt
     4441 ggtctatatg ctctatataa tgctttatgc atctttttac ctctctttag caaaattaat
     4501 aaaaaaatcc ctcattatct aagggattag tcttttatat attaaatgct gtacaccatc
     4561 tatcgactta attccatagg cgttaccaaa acagttagct caacttaggc acccccacgg
     4621 cacacaaaag tgatcactta ccgctgcttc cttccggatc tgacggggtt catgagcttt
     4681 cattgcgcag gacctaagca tcaacaccac ttatttaggg cggccctaca gaaaataagc
     4741 ctttagatgg aattcaatcc tgctatagcg gattgcaggt tacagggcac cgctacctcc
     4801 ccatctagta cagcaaaatt acaaccatat ttaattactt tcattgtttc tggcggagag
     4861 agtgggattt gaacccacga tacagtttta cccatatact cgctttccag gcgagcgcct
     4921 tcgaccactc gaccatctct ccttaatctc tttttctcaa tgccttaaaa aattcttgca
     4981 atatgatcga gcattcttct tgcaaaacat caaaagctac ttttacatta ttattattaa
     5041 aataatctaa tttaaactca tgctgttttt ctatatatga attttttaca tgtcttgtcc
     5101 ctattataag cttttttatt ctagaattaa ctattgcgcc actacacatt atgcaaggtt
     5161 ccattgtaac atataaatca caatcagtca acctccaacc acctaatttt tctgatgctt
     5221 gttttatcgc taaaatttct gcatgtgccg tagagtcttt taacgtttct gtaaggttat
     5281 gagctctagc tattatttga ttatctttaa ctataatagc acctattggt gtttcttttt
     5341 tattatatgc tttatatgct tcttttaatg cttctttcat ataaaatgaa ctttccataa
     5401 ttcctcccaa aacttataac aaacttatct tatcataatt cattttataa ttcaacttaa
     5461 ttttattttg tttatttaat tattactata tatagctata tttttttaaa attagttcta
     5521 aaataatttt tagatattca tacaagagtg ttttataaaa atatttagtg ttttatgatg
     5581 aaaattctgc tgtgtaaatt aacataaaaa aactatgaaa ttaatattta taataatttc
     5641 atagtttttt tatttattgt ttactcataa tatattctct tcatcaaagc atactctata
     5701 tatacaatta atataaattt attttataac atcaacaccc atataaggtc ttaattcttc
     5761 tggaactact acagaaccat ctgcctgctg ataattttct aatatagcag ccaaacatct
     5821 tcctattgct aatccagaac catttaatgt atgaacatat tctgcttttg attttttatc
     5881 tcttttaaat cttattcctg ctcttcttgc ttggaaatct tcaaaatttg aacaagaaga
     5941 tatttctaca tatctattgt aacttggcat ccaaacttct aaatcatatt taaatgcagc
     6001 tgtaaatccc aaatctcctg tacatatttt tacaactcta tatggaagac ctaacatttg
     6061 taacatagtt tcagcatcat gagttaatga ttctaattca ttataagaat cttctggttt
     6121 aacaaattta actaattcaa ctttattaaa ttgatgttgt ctaactaaac ctcttgtatc
     6181 tcttcctgct gaacctgctt cagatctaaa acaaggagta tatgcacagt atttaattgg
     6241 aagctctgca acatctaata tttcattagc atgtatatta gtaacaggaa cttcagctgt
     6301 tggtattaag aaatactcta atccttctat tttaaacata tcttcttcaa atttaggaag
     6361 ttgaccagtc cctataaaac tatttctatt ggccataaat ggaggtaaga cttccgtata
     6421 gccatgctta gctgtatgag tatttaaaaa gaaattcatt aaagatcttt ctaatctagc
     6481 tcctaatccc ctatataaag taaaccttga cccagttatt ttccctgctc tttcaaaatc
     6541 taaaatacct agacctgtac ctatatccca atgcgcttta tgctcaaaat caaatttagt
     6601 aggttctccc caagttctta tttgaacatt gtcttcatct gtttcacctt gtggtacctc
     6661 tggatgagga acatttggta ttctcattaa tgtatattcc atttttgctt ctacttcttt
     6721 tactttctca tcaatacctt ttatcttatc tgataactct ttcaatcttg ccttttcttc
     6781 tgttacatct tttccttctt ttattaattg aggtattttt ttagaattta catttaactc
     6841 atttttcata acttcaactt cttgaagtat ttctcttctt ttattatcta attccactac
     6901 agcatcaagg tcaaattctc tttcacctct tctttccata gcttttttga tatcatctag
     6961 attttctctt attcttttaa tatctaacat attaattcct cctaataatt ttgataatat
     7021 aagttataat tccaacttaa tttacaaaca ttatacttgt aaactcttag tttaaacaaa
     7081 ttttaaaaat aaaaaaagac ctccgtttac cctataaaag ggacgaaaat cttttatccg
     7141 cgttgccacc ctaattgact atactaaaat gtataatcct ctcagaccta taacgtaggt
     7201 aaacgtctag ctttaactag aagctctaga gtagattcaa aaaccattgt aatgagtttt
     7261 caccatccac tcattctctg aatacaatct gttttttact attttccttc acagcttttt
     7321 aactaattgt tttatttgat aatcattata ttatatatat taacatcttt caatactatt
     7381 attcaaattt ttttagaatt ttctttaatt ttttatatta aattcatttt ttctatttaa
     7441 ttaaaacctt atcttttatc cattgtattt agattacctg tattattaaa taataatgaa
     7501 gaaggaacaa atggaacttt tatatcattc tcatcaaatt tattttttac cttttccatt
     7561 acatcaaaat atacatccca gtaatcatca gtttttaccc aaggtctagc aactatttgc
     7621 atggtgttat ttcctataga gtttaaacct attataggct ttggatcatt taatattctt
     7681 ttttcgtttg taaaaatttc atttaatata gacttaacta catctatatc actatcatat
     7741 gaaatattat atgaaaaatc tattcttctt ttgttttgat gtgtgtaatt aattatatta
     7801 ttacttgtca gttgaaaatt aggtataatt atagttttat tatctggcgt cttaagaaca
     7861 gtgctaaata tttgtatgtc agaaactgta ccttctacac ctgaaccttg aatataatca
     7921 cctatattaa atggcttaaa aaataaaata atcataccag agcctaaatt tgataatatt
     7981 tctttaaaag ctaaacctat actaaatcca gcagctccta acacagctac aactgatgta
     8041 gtttgtatcc ctataatacc taagcttatc aatgatataa tagataacat agatatatat
     8101 attccatata caataaaatt atttacacct ttactcattc catatttgat tagaaacttt
     8161 gaaaccatcc ttcttactat tttagatata taaataccta tcacaaatac aattattgca
     8221 tatataatat ttggtatatt atcactaaaa ttatcgagca tattttctaa agttctctta
     8281 gttatattgc tatttgttga ggcagtctta gccaatgata aaaaattcat tcaactcctc
     8341 cttatgataa tattccgttg tcctttaact cttttactat agcttctata gtttcttctt
     8401 ttattgcctc aattgtatga atatggctac attctgtcag aaccgataat tgtttaaatt
     8461 catttgtctc aactttcttc ataaagttgt ctatatccat tttagaataa atattaagtt
     8521 ctgcagttat ctgaccatat gttggatgat ttacgatgac atcttttata ataccaccta
     8581 aatccacaat tatctttaat tcatcataaa tttctttaga atccttatga tttttacact
     8641 ttatttgttt tgtaaaatac ggttgattat atattatata tccttgaggt gtagctatta
     8701 tttcaaatcc tctagctctt ataagggcta tatcttgaac tattacttgc ctacttacat
     8761 ttaatagttc agctagtgtt ccacctttta caggatgctt agattctttt aaaatatcta
     8821 ttaatttact tcttctttca ttagaattca tattacacct tctttccaaa taaaaacttt
     8881 acctatacta tataatttta tattttatct tattataaat caatattgac tttatattct
     8941 atttaatctt aacttttata ataaataaaa aaga
//
LOCUS       DAEHWO010000123         8792 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEHWO010000123 DAEHWO010000000
VERSION     DAEHWO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8792
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.126"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            129..896
                     /locus_tag="KNP54_003682"
     CDS             129..896
                     /locus_tag="KNP54_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HBF0894536.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPYF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     misc_binding    1114..1327
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1581..2615
                     /locus_tag="KNP54_003683"
     CDS             1581..2615
                     /locus_tag="KNP54_003683"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBF0894537.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2656..3873
                     /gene="argJ"
                     /locus_tag="KNP54_003684"
     CDS             2656..3873
                     /gene="argJ"
                     /locus_tag="KNP54_003684"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBF0894538.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3888..4748
                     /gene="argB"
                     /locus_tag="KNP54_003685"
     CDS             3888..4748
                     /gene="argB"
                     /locus_tag="KNP54_003685"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBF0894539.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKETE"
     gene            4778..5965
                     /locus_tag="KNP54_003686"
     CDS             4778..5965
                     /locus_tag="KNP54_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBF0894540.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVILKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            6074..7096
                     /gene="argF"
                     /locus_tag="KNP54_003687"
     CDS             6074..7096
                     /gene="argF"
                     /locus_tag="KNP54_003687"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBF0894541.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7223..7840
                     /locus_tag="KNP54_003688"
     CDS             7223..7840
                     /locus_tag="KNP54_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBF0894542.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(8060..8758)
                     /locus_tag="KNP54_003689"
     CDS             complement(8060..8758)
                     /locus_tag="KNP54_003689"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBF0894543.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
BASE COUNT         3536 a          856 c         1580 g         2820 t
ORIGIN      
        1 ataatcttaa aataatatta tgtaaaataa aaatatatat gacatgatgt tgttgtattc
       61 aaaatattaa gataaaaata tatagaatat atttaaaaat tattatgcaa ttagaaaagg
      121 agataagtat gcagattatt gatataaata taaataatat tgacaatgaa catatatgtt
      181 gttcaatttc tgaaaaaaaa ggagaaaatt gtgttttttc taaaaaagct tggatgaaaa
      241 ataattttga taaaggtcta gtctttaaac gatttgatgt aagaggtaaa gcttttatag
      301 aatatattcc agcagaaaat gcatggtgtc ctattactgc ggacaattat atatttatta
      361 actgtttttg gatatctgga aaatttaagg gtcaaggata ttctaatcta ttgctacaag
      421 agtgtgttga tgatgcaaaa tcaaaaggta aatatggatt agttgtgctt tcgtctagta
      481 aaaaaatgcc ttttttatct gatgctaaat atctaaaata taaggacttt tgtttagcag
      541 atacatcaga accaaattat gagctattat attttccttt tactgataat gctcctattc
      601 catattttaa gaattgtgta aaaaaaagaa aattaaatga gaacggtata gttttatatt
      661 acagtaatca gtgtccacat acggaaaaat atgctcctat tttgaaaaaa attgcaaatt
      721 ctagaggtat tgatgtaaat cttataaaat tcgaaacagc aaaagaagca caaaatgctc
      781 ctgcaccatt tactacatac agtctttttt ttaatggtga atttgtaacc aacgagatac
      841 tttctgagaa aaagattgag aaatttttag ataccaacat taaaaaattt aactaaaaag
      901 agatgtaaat attgtatttt gaaaatatat tattttataa tttaatatat tttggatgtt
      961 ttttaaattg acgaatgaaa tataaaaatt atatcgcaat ttagatacaa aatgctggaa
     1021 attaaccata tagaaaatat ttccaaaaat ttaaaaatta tattgacaaa gttaaaaaaa
     1081 taaactatca tataaaacaa taagaaaata aattgaaatc ctgtgaaaaa gagagtagca
     1141 taaagctagt tgatagagag ctgggaatgg tggaagccta gtaacgaatt ttattgtgaa
     1201 tagagctttg gaggagatta ccagaagtaa tagtatggta attggtgaat ctcgccttaa
     1261 gagattagag tgggtaagat tatcttatca attagagtgg taacgcgggt gtatattcgt
     1321 ctcttggtct ttgaccaaga ggctttttta attttaaatg tacattttgt agatactttt
     1381 taatttgagt tttaatgatt attgtaattt taccaataag agtggtaccg cggaaaatcg
     1441 cctcttagta tttataatgc taaggggttt tttgttttaa ttagagtatt ttaatctacg
     1501 tattatcaaa tgattatcat atagtaaagt ggaaagatag gattttaaga ctatttgaat
     1561 ataaaaatgg agggaacaaa atgaataaaa taaaagttgg tattattggt gcaactggat
     1621 atgtcggggc agagttgatt agattattaa tgaatcatga taaagtcgaa gtgacagcga
     1681 taggttcaaa ttcgtatgtt ggaaaagata tagttgatat atatccaagt ataggatata
     1741 aaaataacat gatatgtata gaaaatgaaa aagttataga tatgtgtgat gttgtattta
     1801 cagcccttcc acatggagtt agtgaaaagt ttgtaataaa ggcaattaaa tcgaaaaaga
     1861 aagttataga tttaggtgct gactttagaa taaaagatga agaagtatat agtaaatggt
     1921 atggagtatc ttttatagat aaaatcttac ataaaaaagc tgtatatgga ttaagtgaaa
     1981 tatacaaaga agatataaaa gatgcagata taattgcaaa tcctggatgt tatccaacta
     2041 gtatttcttt accattgatg ccattactaa gttctaaatt gataaaaaat aataatataa
     2101 taattgattc taaatcaggt cttacaggtg ctggtagaga attatcgatt agtagtcact
     2161 ttacggaggt taatgaaaat atcactgcat ataaaatagg gaagcacaga catactccag
     2221 aaatagaaca aaatttaagt gaatcctgca aagaaaaagt aagtgtagtt tttacaccaa
     2281 acttaatccc agtaaatagg ggaatcttat caactatata ttgtacaaaa gaagataata
     2341 tttctataaa tgatatacat aggaaattaa ctgattatta tgaatttaaa gaatttatag
     2401 aaattcttcc attagataag gtagcttctt taaagaatgt tagattctca aataaatgtg
     2461 taatatcatt acatgaaaat ggagatacat tgataatctg ttcagctata gataatatga
     2521 ttaagggagc agcaggtcaa gctatacaaa acatgaatat aatatttggt attgaagaaa
     2581 atacaggttt aaaaaatatt gcaccatcat tttagaaata aaaaatacta aactcatata
     2641 attaggagga taaatatgga gattataaag ggtggagtta cagtttcaga aggatttttt
     2701 gcttcaggga ttcactgtgg cttgagaaaa aataaagaaa aaagagattt agctttggtt
     2761 tattcagatg ttttatgtga tgcagcagca gtagtaactc aaaataaagt aaagggcaat
     2821 cctgtttatg ttacacagga acacattaaa aatggaaaag cacaagctat catagtaaat
     2881 agtgctaatg ctaatacctt taatggaaaa gaaggactta taaatgctta taaaatggct
     2941 aaattcacca gtgataaatt aaatattaaa gaaagtgatg ttttggttgc atctacaggt
     3001 gttataggaa agccattaaa tatagattta atagaagaaa atatggatga attagtgaat
     3061 aatctaagta aacaaggtca tattggagca agagaagcta ttatgacaac tgatattata
     3121 aaaaaagaaa tagcagtagc aataatgtat ggagataaaa aaataactat tggaggtatg
     3181 gcaaaaggtt ctggcatgat acatcctaat atggcaacaa cgttaggatt tataactaca
     3241 gatgcaaata ttgatggagt tttgctaaaa gaagctttaa aaattgctgt tgacaaaagt
     3301 tttaatagag ttagtgtaga tggagataca agtactaatg atatggtaat gattctagca
     3361 aatggaaaag caaaaaatga tagaataaac aaaaaagatg aacattatca agtatttttg
     3421 agtgcactta catatgtctg tatagaactt gctaaacttg ttgcaaaaga tggagaagga
     3481 tgtacaaaac taattgaatg ctatataaat ggagcattaa gtgaagaaca tgcagtaaaa
     3541 ttagcaaaaa cagttatatc ttcttcatta gtaaagacag ctgtatttgg agctgacgca
     3601 aattggggta gaatactgtg tgctttaggt tatgcaggtg aagaaataga tatggaaaaa
     3661 gttgatatta tttttgagag tatgaaagga tatattgaag tatgtaaaaa tggaaatgga
     3721 ttagatttta atgaggaaaa agcaaaaaaa atccttgaag atgacgaaat aagtatatta
     3781 gtagatttaa atatgggcaa tgccagagga aatgcatggg gatgtgattt aagctatgat
     3841 tatgtaagaa taaatggaag ttatagaaat taggaggata tactttaatg attaatatag
     3901 aaaaagcaaa tacacttata gaagctttac catatataga aaaacatcag ggaaagacta
     3961 ttgtagttaa gtatggtgga agtgcaatga aaaaagatgg tctaaaagaa tctgttatgg
     4021 aagaccttgt gttaatgagt tatgttggaa tcaatatagt tttagtacat ggtggagggg
     4081 cagaaatcaa taagatgcta gcaaaagtgg atatagaaag taaatttgta aatggtctta
     4141 gatatacaga tgaagagacc atggaaattg taaaaatggt acttgctgga aaggttaata
     4201 aagacttagt aaataaaata catacaaaag gtggaaaagc agtagggctt tgtggaatag
     4261 ataataatat gattttatgt gacccatata aaaattatga acttggattt gtaggagaaa
     4321 tcaaaaaagt aaatgttgag cttatagaat cttgtctaaa gtcaggttat atttcagtaa
     4381 ttgcaactat aggtgttgga gatgatggag agacttataa tataaatggt gacacagcag
     4441 cttctgctat agctaaagag ttaaatgcag ataaattgat acttcttaca gatgtccctg
     4501 gtttgttaag agagccagat gaagaaaaat cattaataac agaagttata ttagaggatg
     4561 ttgataaatt atttgaagaa ggtataatta ctggaggtat gatacctaaa atagagggat
     4621 gcgtagatgc cttaaataac ggagtaaata gggtacatat tttggatgga agagttccac
     4681 attctataat aacagagcta tttactgata gtggaatagg tacattaata agaaaagaaa
     4741 ctgaataaaa ttataagttt aagaggggag aataagaatg aataacgaca atacaatttc
     4801 aaaatggaat gaatatttta tagatacata taaccaaccc aattttgtca tagattatgg
     4861 tgaaggaagt tgtttttttg atactaatgg caataaatat atagatttta caagtggata
     4921 tggagtatct tctcttgggt atagtaatag taatttaaag aatgctctaa aagagcaagt
     4981 agataaatta ttacatactt caaatttata ttttaatgag ccagtgttgt attcaggaga
     5041 gaaaataatt aattcaagtg gaatggctaa agtatatttt tgtaattctg gaacagaagc
     5101 aaatgaaaca gcattcaaaa tagcaagaaa gtatagtagt gacaaatatg gtaatggtag
     5161 aggaactatc ataagtttaa aagactcttt tcatggtaga acaatgatgt ctttaatggc
     5221 aactggtatg gacaaatacc ataagtattt ttatcctctt cccgaaggtt ttaaatatat
     5281 agaaagaaat aatattgaag atttaaaaaa taatcttgat tccacagttt gtgcaataat
     5341 tcttgaagcg attcaaggcg aaggtggagt taatgttctt gaaaaagatt atgttttgga
     5401 aatagtaaaa atatgtcaag aaaaggatat tgtagtgatt tttgatgaag tccaatgcgg
     5461 tataggaaga actggtaaac tttttggcta tgaatatttt gatgtaaaac cagatatagt
     5521 taccgtagca aaagggttgg gagcaggaat accagtagga ggagtattgg taaataaaaa
     5581 actttcaaaa gtactaggaa aaggagacca aggtacaact tttggaggta atttattagc
     5641 tatggtggca gcttcagttg tattagatga gatatctaaa gatggctttt ataatgaagt
     5701 attagaaaaa ggaaattata taagaaaatc tattgaaagt tttaataaca aagttatatt
     5761 aaagacaaaa ggtattggtc taatgatagg aattgaaact aatattgaat ctagtattat
     5821 agaagagaaa gctagaaaaa aaggattgct tattttgact gctggaaaaa atgtattgag
     5881 atttttacca ccattaacaa tcagttataa ggaaatagat gaggctcttg aaatcctaaa
     5941 agatatatta ctagaaatta actaaatatt caaaaaatag ttgattaaag ataaaaatta
     6001 gaagtaaata aaaaagtaaa gtgctaacaa gtttaattga atttaaaaag tttataagaa
     6061 ggggcgaatt aatatgaata atataagttt aaaaggtaag agttttttga cattaaagga
     6121 ttttacaaaa gaagagatta gatatttatt aactttatca agttatttaa aaactaagaa
     6181 aaaagttggt ataaaaggcg atttgctaca aggaaaaaat atagctttat tatttgagaa
     6241 aacatcaaca agaactagat gttcatttga agtagcagct catgatgaag gagcacatgt
     6301 aacttatcta ggtccaaatg attgtcatat gggtaaaaaa gagtctgtat cagatacagc
     6361 aaaagttcta ggaagattct atgatggaat agaatttaga ggctttaaac aagaaacagt
     6421 tgaaagtcta gcaaaatatt ctggtgtacc tgtttggaat ggacttacag atgaatatca
     6481 tccaacacaa atactggcag attttttaac agtaattgaa aatgtagata aagatttgaa
     6541 taaagttaaa tttgtatatg ttggtgatgc tagaaataat atggggaact cactgatgat
     6601 aggatgtgct aaaatgggaa tacatttcgt agcactagca cctaaggaac tttggccaaa
     6661 tgaagaattg gttaaggaaa tgaaggaaat agccaagaaa tccaaaggag atataatgtt
     6721 gactgaaaat attgatgatg ttaaaggtgc agatgttata tatacagatg tatgggtttc
     6781 tatgggagaa gaggagcaat atgaagcaag aataaatcaa cttaaagatt atcaagtaaa
     6841 tatggatatg ataaagaaaa ctgaaaatga aaatgttata tttttacact gtcttccagc
     6901 atttcatgat ttagaaacta aggttgctca ggagatttat gaaaagttcg gattatcaga
     6961 attagaggtt acaaacgagg tatttaattc aaaatattca aaggtatttg aagaagctga
     7021 aaatagaatg catacaataa aagctgttat ggtttctact atgactgatg taaatatgaa
     7081 caataattta atatagatat gttttaatat agactttact ttaatgaaaa tttataaaat
     7141 attttaaata tattattcaa aaactctcat tatatgttaa aataacttat gtatcaacaa
     7201 attaagaggg aggatttgag atatgaaaaa aatcatatta gctttaacaa cttttttatt
     7261 agcaatatct ttaacagcat gttcaagtgc aaaaccagaa gatacaattg atagtttttt
     7321 taacagtgcg aaaaagtttg actttgaagg catgaataag gtaatggaaa ataatgacga
     7381 aaaatataag gatatattaa aggaattaga tacaaaagac ccaaatgccc aatatgtttt
     7441 agattatcta aaacagaatg catctaaaat cacatataca ataaaagaca gcgaggttaa
     7501 aggtgataag gctacaatca aagtagaatg taaatttata gattcaacac cattacttca
     7561 agaaatagta gctgaggcat ttacaaagat gattggtatg agtttttcag gacaagactt
     7621 aactgatgag aaaacaactg aaatgttagt atcaattatg aaagaaaaac aaaaaagcgt
     7681 taaagagact tatgttacaa aaaatgtaga gtttgaatgt tctaaaaagg ataataaatg
     7741 gataataagt tcagtaaatg atgcagtagc tgatgtattg ttatctaatc ttgttacagc
     7801 aggacaagaa ttttctaact ctatgaatac acttgaataa tattgtttag gtgtagtaaa
     7861 gtaataaata tatgattatt tttataaata aacatataaa tatttatgaa ggataccatt
     7921 tttggtatcc tttttattaa tataatgaaa tacatggtta atttctatat tgtcaagaaa
     7981 ctatgatata tgttataagt ctatactatt taaaataaac ttataacata tattttttat
     8041 aatatagtgt atgaaaaatt tatttaacta attttagata tttattgaca actgattcag
     8101 ccaagcattt tgatgaatca acaatattta ttgaaggata tgatttttct aaaactacat
     8161 ttaaatcagt acaagcaatt actatatttt ctatagattc atttttaaca tcttcaataa
     8221 gtttattcca aatatcaata ttgtgtggat tttctttatc catttttata ttttgaataa
     8281 gattgtttaa ttttatttgc cattcatctt taaatataaa ttcatgtcca ttatgtatta
     8341 taccattctg gtaaattgta gactcaaaag ttgaactagt cgaaaaaaga gttacttttt
     8401 gtgagatagt aggtaatttt ttaactgttt cttctacaat atttaatatt ggtatattaa
     8461 tagactcttt taattcttta aagtatatat gtgctgaatt gcatggcatt gcaataaaat
     8521 ttacaccagt tgattcaagc ttttgtaatc catcaattat agtttctttc ataaggtcat
     8581 gatttattgg acggtcaata taaaatgggg taggtaatga atatatcatc atctttggaa
     8641 attcatcatc atattttgct ccatattgag attgacactc atcaataatt aaatcaacaa
     8701 aaggggctgt tgaccttgga cccattccag ccaaaatacc aattaatttt tcattcataa
     8761 aaattatctc ctttatatat aaatatattt at
//
LOCUS       DAEHWO010000124         8609 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEHWO010000124 DAEHWO010000000
VERSION     DAEHWO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.127"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(69..452)
                     /locus_tag="KNP54_003690"
     CDS             complement(69..452)
                     /locus_tag="KNP54_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0894544.1"
                     /translation="MLNRKLPDAELKIMKYIWNTGYKTVISKDVADEIEKTYGWKHTT
                     TITLLARLTKKGFLISQRIGKHVHYTVLVKEREYLKLEGKRIFGGLHNNPLSELISKL
                     HDGEEITEEKIIEIGNWIKSWKDED"
     regulatory      681..778
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(981..1124)
                     /locus_tag="KNP54_003691"
     CDS             complement(981..1124)
                     /locus_tag="KNP54_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894545.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
     gene            1383..1571
                     /locus_tag="KNP54_003692"
     CDS             1383..1571
                     /locus_tag="KNP54_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894546.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            2273..2794
                     /locus_tag="KNP54_003693"
     CDS             2273..2794
                     /locus_tag="KNP54_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBF0894547.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDDSFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            2770..4356
                     /locus_tag="KNP54_003694"
     CDS             2770..4356
                     /locus_tag="KNP54_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894548.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYPIIWYH
                     NKGKNNDIEFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKALDKILID
                     RNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKILIAKRS
                     DNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQPIPLAI
                     YQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENTVPDFKE
                     TLKLAFKKLNENQLQESTNM"
     gene            complement(4420..4938)
                     /locus_tag="KNP54_003695"
     CDS             complement(4420..4938)
                     /locus_tag="KNP54_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894549.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(5104..5466)
                     /locus_tag="KNP54_003696"
     CDS             complement(5104..5466)
                     /locus_tag="KNP54_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894550.1"
                     /translation="MEDLCMDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRA
                     ANNLHELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDI
                     IREYETYRGRYLTFNWKR"
     gene            complement(5547..6359)
                     /locus_tag="KNP54_003697"
     CDS             complement(5547..6359)
                     /locus_tag="KNP54_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0894551.1"
                     /translation="MKICITVGHSILKSGACTSADGVINEYQYNKSLAPVLADTFRKE
                     GHKVDVIICPEKQFKTKNEEKSYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICDKLGTVFKNRGAKLDKRLYILNSSKPTAVLIESFFCDNKEDYDKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKILANVLSWGYSPSKVLVCD
                     IKDYVPGQTENLYVVGGGACEKISSITKEKFIMIKGNDRFDTLYKALDFINR"
     gene            complement(6359..6850)
                     /locus_tag="KNP54_003698"
     CDS             complement(6359..6850)
                     /locus_tag="KNP54_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBF0894552.1"
                     /translation="MHLKDLDNSRSFLIQKLGGNMNLTIVFLATNIFIKLVILAIAFD
                     TLLGCLRAIKTHQFNSSFGINGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWIDF
                     LRLNHLGISEFFSILFILYESVSILKNMYLCGLPVPKKLKEKIGNLLDTMTDELNIKG
                     GNK"
     gene            complement(6858..7076)
                     /locus_tag="KNP54_003699"
     CDS             complement(6858..7076)
                     /locus_tag="KNP54_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894553.1"
                     /translation="MKKIIVICILVLMLIIPTMGEIFIMVENIKLEGLEQNPTSCYIS
                     NPGIMGEAKCDAAYFIIAADFVNNLKVK"
     gene            complement(7174..7356)
                     /locus_tag="KNP54_003700"
     CDS             complement(7174..7356)
                     /locus_tag="KNP54_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894554.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFELDDVTNTEYRKAVED
                     YIIRESGVVEGAEPTK"
     gene            complement(7356..7649)
                     /locus_tag="KNP54_003701"
     CDS             complement(7356..7649)
                     /locus_tag="KNP54_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894555.1"
                     /translation="MNVPNRVIYDQTGKIIFETGESCGDVLPHNKITELDYIDIPYGS
                     IDYIKNRIIGINIETKQPILEEIPVYVSEEKKRIQELENQVLLNENEKVGGLL"
     gene            complement(7665..>8609)
                     /locus_tag="KNP54_003702"
     CDS             complement(7665..>8609)
                     /locus_tag="KNP54_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894556.1"
                     /translation="LITLLQALPFLTVSSYNSTQATFKADHTDPTLLTKIEVFIDDVL
                     KETITTDLTTEKTINYTLEDNALHTLKIVVTDSNNATAEKVLSISKNIMPLPENVNLN
                     DISTKLVEVNAGFKVGKTSIINTLALKNIEASLNNTLVELSEKIKQSFDSGDASLQDL
                     MNQLTQANNTISQLNSKYKVASGTVTSFADSAKIAYPYLTDRTFKPGTWVKISNLDFK
                     PNIFFADFDYYDTEYKNNYKLFLFACRGVATQRGVDFSSVTAFIRKNSDENFHANGWL
                     YNNSEGDVYFNNTGVQIPAYNFDSTQRHIYKWYAIKFI"
BASE COUNT         3095 a         1237 c          990 g         3287 t
ORIGIN      
        1 acaacttatc cccaatatta tccacaagaa aaaaggtagc acttatatta gtagctacct
       61 tttatttatt aatcttcatc tttccagctt tttatccaat ttcctatttc tattattttt
      121 tcttcagtta tttcttctcc atcatgcaat tttgaaatta gttctgacaa gggattgtta
      181 tgtaaacctc caaaaattct tttaccttct aattttagat actctctttc ttttactaat
      241 actgtatagt gtacatgttt cccaattctc tgcgatatta aaaaaccttt tttggttaat
      301 ctagctaaaa gtgtaattgt agttgtatgc ttccaaccat atgttttttc tatttcatct
      361 gcaacatctt ttgatattac agttttataa ccagtattcc atatgtattt cataattttt
      421 aattctgcat ctggtagttt tctattcaac ataatatatt ccttctttca atttatgtca
      481 cttcttcaaa tttatctagc ttaaattaat aataggagct ttttaggaca aaaactatag
      541 gtaattttta ccatatattc tactgtttta gtttgttttc ttagaagaaa aataactttc
      601 atatctataa aattattcaa ctttcaaact atcctgttga ataataacta attctattgt
      661 attattttag ttgtagaata aaactaaatc ggcaaaacta gagaaattta gtgacgcaaa
      721 gctataggga ctaagactta tataaatatc ttatgagtta tgtcagccag ttgccaaaaa
      781 gatagtgttc tttttgtttt tatgaaagtt ttttaggggg ataataatat atatacttag
      841 agataaaata aaatatattt ctagcattca cagttttatt ttttcttaaa atgcgatata
      901 ataaagatgt aaattcgtat caaaaacaaa aaaagaaact acaatctatt agcctagagt
      961 gaagtttcat taactaaata ttaatgtcgt tttttattaa acttgatttt tacatcaagc
     1021 tcaaagtcac tcctgccaga gtggcttttt acttttctgg aaataatata tgtaataaag
     1081 ctagctgtta aactagctaa cactcctagt aaaaattcgc tcatttctcc acctccttcc
     1141 ttttaaggga tggaatgtag aaaatgaagc tccactctta gattgtagtt ccacaagatt
     1201 attcttgcat tttaattata acataatttt acaattatca aatatccatt ctccatattt
     1261 ttttatttat acaatatatt ctatattgca ataaaaaaca ttgttttaaa tatatataca
     1321 taggtatata ctaaatatgt taaacttaat tatggaaaat ataaaatgaa aggaataaaa
     1381 atatgactaa gactatatta tgtgattact gtaataaagg aataaataaa gatgataata
     1441 agtatattac ttttcataag aaaagtcata tgaaaactaa catttgtatt aattgtgcat
     1501 taaatttgat agataaagat aaattaaatg aaaatattat aaataatcaa catgattatt
     1561 caaagaaatg aaaaagcact ctccataatg aagaatgctc tatataataa tgtttgactt
     1621 agtaaagatg tgttggggtt acatatttac ttttttatta tatcatataa ctttgtgtat
     1681 gaaaaagaat ttaaatcaat tttaaggtgt gttgagtaat gttcttgata gtttatatgt
     1741 tgatgaattt caaaaaaata agcactctta taaaaagagt acttttggta tatattcaag
     1801 catttatcta atacaattat agcatgtatt atgttttagt atgataattt tcgttcgttt
     1861 tattattaca acttctacta tagttttcat actttaacat caactaaatg aatttaatta
     1921 agattactag ttaatcgttt tttggttctt tcatattctg aaatctaaaa ttttattatt
     1981 tgtttattgt tattatttaa cacatgttgg tatttcaacg atttatctta ttgttaatat
     2041 tcttattgct tccaaagtat atctaattat ttttaagata atttactaat ttttattttt
     2101 tcaaacatac attcgacaaa aaacagtttt tatatggtat aattatattg tataatacaa
     2161 aaggttaatg aaaataatta atattaaatg taccaaaaaa aatagttttt gatataatga
     2221 atattataat aaataattat ttaaataaaa tattatataa ggatgtgatt ttatggattt
     2281 caaaatcaga gagctaatta atgatataac ccaagatatt atccaaacat acaaaatcca
     2341 aattccaata gtaaatataa atcaagttgt tgatgcttta ggaggcaagg taatagaaga
     2401 tagttcttta agtggatact ctgatggatt tattagaaaa gttgatgatt catttgaaat
     2461 agtggtatct ccttatcaac cagataccag aaagaatttt accattgctc atgaacttgg
     2521 acatttattt ttacacatgg gttatggcat tgatgatgaa ctatggaata gtcaagatgg
     2581 aaatcagtat tttagaagtg gcaataccaa taaggagtat caatccaatg aatttgcagc
     2641 agccttgttg atgcctaaac atgaatataa aagaattatg gatgaaaaca cagtaggtaa
     2701 taaggtcgac acttcaaaaa ttgcagaata ctttaatgtt tcctcttatg cagcatctaa
     2761 tagagggaaa tggttaggat atttacaatg gtagatgata aagaatataa aactcaaaat
     2821 gtaaataatg ttcataattc agctaaaaac gaaaacgctt ttaatcttaa aaagtataag
     2881 gaaaaacttc aagaaaatat taatactgat atttatgaaa aagaaaaaga acctaatcat
     2941 ccagaagtga ttttgttctt ttcttttgat atagctaatt catcattata taaaaatata
     3001 aattatagcg gatgggctaa ggtattatca catataattc gtaagttaca atatagagtt
     3061 tatgaaaacc ttaaagcaca actttggaga gttcttggtg atgaggtaat tttcattatc
     3121 gtactaaaaa attatgatga aatttataaa tacatagata taatctttga tattttaaca
     3181 agcactgcta aagatataaa aagtggtaat atattctcta cactagaagg attttctgaa
     3241 tctgaaaaat acttaatgaa acttcaaaat attatttcat taaaaggagc ggcctggatt
     3301 gctatagtat caagaaatcc taattttaat gctttagaaa ataatgaaca atatgaaaat
     3361 atttctgcta tgtacgattt atccaataat tataaaatat ttgagttctt aggaaatgat
     3421 attgatgctg gtttcagaat atcaaagcaa acatgcccag aaagacttgt tcttagtttt
     3481 gaactagctt atatattatc aagaaaaact gatattttat ctaaattaca tataattaca
     3541 tataaaaaat taaagggtat ctggaaagat aaactatacc ctatcatttg gtatcataat
     3601 aaaggaaaaa ataatgatat agaatttgat gatagttttt cttttgatga aatagaagaa
     3661 aatgaattgg ttcgagaata tttttttaat aaaaaaggag aaagtaaatt actaattgat
     3721 tcttttatgt ttaattctgt agacaaggct ttggataaaa tacttataga cagaaacctt
     3781 agtgataaga ttgaaaaaat aggtgacgta atttctaaaa caaaccccag ttatgataaa
     3841 aatacaatag ataaagacta tataaaagta gatttaatgg aattacactg tgttgcggtt
     3901 tgttataata aatcaacttc aaaaatatta attgcgaaaa gaagtgataa tagaaataat
     3961 aatgcgagta aatgggaatt tggttgtgct aaggcaagtc tagaaacttc aattataaat
     4021 actattaaag atgaatatga aaaagatttt aatataaaca ttgaacctat tactgattgc
     4081 acaagaaaag atgattgcca acctatacct ctagcaattt atcaagttaa aaaaagtgat
     4141 ggtttacaca aaggcattat aactctcgca gaaataataa atgattatga tatttctaaa
     4201 tttgaaccca catcaaaaca taatgaactt gcatggatag gagaggatga acttgaagat
     4261 tttaatgaaa acacagtacc tgattttaaa gaaactttaa aactagcatt taaaaaatta
     4321 aatgaaaatc aattacaaga atctacaaat atgtaaatag tattcttcta tgatttgatt
     4381 ctatcttcat agaggaatac taaccaaata aaacattttc taaatagcat taaaaactac
     4441 tacaagtata tatataaaca atataatacc acctaaaata aaagcttcta ctgacttttt
     4501 tacattatac attttcttat cacagattaa agataattct tttatttgaa caagtgcatc
     4561 attaatcaag ttttcttcgt ctttaaatgc attttcaaat gcttctttgt actgttcatt
     4621 atttaaagat gctatctctt tataataaaa aatagattta tattcatttt ctattttaga
     4681 attccttggc tttaaaacca taatcgaaaa ataaattgaa ataacaaata tacataatat
     4741 aacaatgtaa aatagcatct ctaaacatct gatattactt atacttaagt gattcattat
     4801 tttttccttc cctgaaaata aaaaacctat aattgcgcta tttaataata gtaaaaaact
     4861 agctttatta tctgattttt caatatagta atcaattcta tttactataa acttcgctat
     4921 gtctattttt ttatccatga ttttactacc tcatttcatt aaattttata ttgattcaaa
     4981 attttatttt ctacttatta tcattgaata aattattatt tggaaataat cttattgaaa
     5041 taataaaaat atgtgaaaga aagtaataac taactataat tactacttcc taacttaaac
     5101 attctatctc ttccaattaa aagtaagata tcgtcctcta taagtttcat attctcttat
     5161 aatatccaat atttcctccc tagaagttgc aattaaactt ctatcaaata gttcaatcat
     5221 tctattgcta tcattatcag aaacattaca agactctaat atctcattat taaatattgc
     5281 aatagcatac ccagtaccta tttttatctc atttaattca tgtaaattat ttgctgctct
     5341 aaagatatca gcttcagcca atccacctaa atcttcgctt ctattaatca agttattaag
     5401 tttaatacta aaagctgctc ttacaaatct ctcataaacc aatgcatcca tacataaatc
     5461 ctccattatc acaataatat atttacatta tattacaata atagagttat cacaacaaac
     5521 aaccacttct agttgataac ttttatctat ctattaataa aatccaatgc tttataaagt
     5581 gtatcaaatc tatcattacc ttttatcata ataaattttt ctttagtaat agaacttatc
     5641 ttttcacatg cgccacctcc tacaacatat aaattttccg tctgacctgg tacgtaatct
     5701 tttatatcac aaactaaaac tttgcttgga ctatagcccc aactaagcac attcgcaagt
     5761 atcttatcaa cttctccatc ataaacaatt gtatgtttgt acatctgttt aactccctca
     5821 ttatttatat ttttatttaa tacaccttct acaattaact tagcaatacc ttcatgacct
     5881 agtttcttag ctttatcata atcttcttta ttatcacaga agaaactttc aattaatact
     5941 gctgtaggct ttgaactatt taagatatat aatcttttat ctaatttagc acctctattt
     6001 ttaaatactg tacctagttt atcacatatt ctagttgcat actctaagcc tttattacta
     6061 taatatagga cttctgaacc tttaccttga ccgttacttg catttaaatg taactctata
     6121 agtaaatcat atcctccact attaactcta ggtattttat aagacttttc ttcattctta
     6181 gttttaaact gcttttctgg gcatattatt acatctacct tatgcccttc ttttctaaat
     6241 gtatctgcta atactggtgc aagagatttg ttgtattgat actcgttaat tactccatca
     6301 gcagaagtgc atgctccact ttttaaaata ctgtgtccta ctgtaataca tattttcatt
     6361 atttattacc tcccttaata tttaattcgt ctgtcattgt atctagtaaa ttgcctattt
     6421 tctcctttaa ttttttggga actggtaatc cacataagta catatttttt aatatactta
     6481 cactttcata caaaatgaat agaatagaga aaaattcaga tattccaaga tgatttaatc
     6541 tcaagaaatc aatccaatct tgtggcaaca taaataaaaa gttaaacttt gtaagtatat
     6601 caactactgc tagaaaaaat atacatgcta tcattgcaac ttttcttatt cctccattta
     6661 ttccaaaact tgaattaaac tgatgtgttt ttattgctct taagcaacct aacagtgtat
     6721 caaatgctat tgctaatatt actaatttta taaatatatt tgttgctaaa aaaactattg
     6781 ttaaattcat atttcctcct aatttttgta ttaaaaagga cctagaatta tctaagtcct
     6841 ttaaatgtat taatttatta ttttaccttt aaattgttaa cgaaatctgc agctataata
     6901 aagtatgctg catcacattt tgcttctccc ataatccctg gattagaaat gtaacaactt
     6961 gttgggtttt gttctagccc ctctagcttt atattttcta ccattataaa tatctccccc
     7021 atagtaggta taattaacat tagaactaga atgcaaatta caattatttt cttcattttt
     7081 taatctcctt ttaatagaat ttttttatta tagataaaaa taaaaaatat ataactaaaa
     7141 aaggaaatta tttttaattt atataaaaaa aacctatttt gttggttctg ctccttctac
     7201 tactccactt tctctaatta tataatcctc tactgctttt ctatactctg tgttagttac
     7261 gtcatctaat tcaaattctc gattttttag agggtttaat cctccgttta atatcctctc
     7321 tgctaatatt cttactacaa cattatttat attcattata ataatcctcc tactttttca
     7381 ttttcattta ataaaacttg attttctaat tcttgtattc tctttttttc ttcacttaca
     7441 tatactggta tttcttccaa aattggttgt tttgtttcta tatttatgcc tataattcta
     7501 tttttaatat aatctatact tccatatgga atatcaatat aatctaattc agttatttta
     7561 ttgtgtggta acacatcccc acaggactca cctgtttcaa aaattatttt gcctgtttgg
     7621 tcatatatta ctctgtttgg aacattcata tttttttctc cttcttaaat aaatttaata
     7681 gcataccatt tataaatatg tctttgagtt gagtcaaagt tataagctgg aatttgaaca
     7741 ccagtattat taaaataaac atccccttcg gaattattat agagccaacc attagcatga
     7801 aaattttcat cactgttttt tctaataaaa gctgtaacgc ttgaaaaatc aacacctctt
     7861 tgtgtagcga caccacgaca agcaaaaagg aaaagtttat aattattttt atattcagta
     7921 tcatagtaat caaaatcagc aaagaaaatg ttaggcttaa aatctaaatt actaatttta
     7981 acccaagtac caggtttaaa agttctgtcg gttagatatg gataagcaat tttagcacta
     8041 tccgcaaaag aagtgactgt tccactagca actttatatt tagagtttaa ttgcgatata
     8101 gtattattag cttgtgttaa ctgattcatc aaatcctgta aactagcgtc tccactatca
     8161 aaagactgct ttattttctc tgataactca acaagtgtgt tattcaaact tgcttctata
     8221 ttctttaatg ctaaagtgtt tataatactt gttttcccaa ctttaaatcc tgcattaacc
     8281 tcaactaatt ttgttgatat atcatttaaa tttacatttt cgggcagtgg cattatattc
     8341 ttacttatac ttaaaacttt ttcagcagtt gcattattgc tgtctgtaac aactatttta
     8401 agcgtgtgca gtgcattatc ttctaatgta tagttaattg ttttctctgt tgttaaatct
     8461 gttgttatag tttcttttag tacatcatct ataaatactt ctatcttagt taatagtgta
     8521 gggtctgtgt ggtcagcttt aaatgttgct tgtgtggagt tataagagga tacggttaaa
     8581 aaaggtaatg cttgtagtaa tgttattag
//
LOCUS       DAEHWO010000125         8531 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEHWO010000125 DAEHWO010000000
VERSION     DAEHWO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8531
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.128"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            231..1310
                     /locus_tag="KNP54_003703"
     CDS             231..1310
                     /locus_tag="KNP54_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBF0894557.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIVKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="KNP54_003704"
     CDS             1634..2002
                     /locus_tag="KNP54_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBF0894558.1"
                     /translation="MNVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKSLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="KNP54_003705"
     CDS             2119..2922
                     /locus_tag="KNP54_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0894559.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDRQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYMGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3314..4204
                     /locus_tag="KNP54_003706"
     CDS             3314..4204
                     /locus_tag="KNP54_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBF0894560.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDSCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
     gene            4767..5210
                     /locus_tag="KNP54_003707"
     CDS             4767..5210
                     /locus_tag="KNP54_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0894561.1"
                     /translation="MIEIKTIEINKKSRIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5382..5552
                     /locus_tag="KNP54_003708"
     CDS             5382..5552
                     /locus_tag="KNP54_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894562.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5925..7022
                     /locus_tag="KNP54_003709"
     CDS             5925..7022
                     /locus_tag="KNP54_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBF0894563.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIAKGKREEKFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            7227..7715
                     /locus_tag="KNP54_003710"
     CDS             7227..7715
                     /locus_tag="KNP54_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBF0894564.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7801..8208
                     /locus_tag="KNP54_003711"
     CDS             7801..8208
                     /locus_tag="KNP54_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894565.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8209..8427
                     /locus_tag="KNP54_003712"
     CDS             8209..8427
                     /locus_tag="KNP54_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894566.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
BASE COUNT         3326 a          848 c         1508 g         2849 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagccttta
      601 tcatcaagga cgaagagcgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggct gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacccg tactgcctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgtaaagg attggtacgg taaaaataaa tccactaact
      901 ggattgtaaa gcatggttgc agaactctac taaaaaaagg caatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagcc atataaatta gaatttgtag
     1621 aggagaaata taaatgaatg tatatagttt ttggaatgac actttggcac aagatgctgt
     1681 taagataaga aaatattttc atgaagatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaagg gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaatca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtgtttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccag atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gatagacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaattgttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gttacgaaaa aaaagaactg tgtcatctca tgtatatggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaactaca tactcattag
     2941 gtaaattatg tagtatatgt gtttacagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat atataaattt
     3061 ttaagcgaaa tacatcaaaa gaaggattag aattagtgga gacagaacag ctattataga
     3121 ttataaataa atagttttaa aggagaggta ctacgaatat agaggaaggt aaatcatacg
     3181 ttattcaagt attataaatg attagtttaa aagtactatc ggataggagt ctccatattt
     3241 aaaccttagt aaaggtagtt aaagtagtag tttaaaaact aaaaaattat ataaaggaat
     3301 taggtataag aaaatgattg agagtatacc agcaaaacaa attttacaaa aagtgaaatt
     3361 tgacaataca agatggtttg gaattgacta taatatgaat ctctatcgtg gttgttctca
     3421 tggatgtata tattgtgata gccgtagcac aatatacaac atagagaatt ttgacaaagt
     3481 tagatataaa gaaaatgtga tagaaatttt aagtaaagaa ttgcgttcaa aaagaaaaaa
     3541 aggtgtagta ggcattggag ctatgtctga cacatataat ccttttgaaa agcaactttg
     3601 tattacaaag caagcactag atttgatttc ggaaaatcat tttggagtgt ctattgatac
     3661 taaaagtagt ttggtggtta gagatatacc gattttgcag aaaattaaaa aaaataattc
     3721 tgctattgta aagttgacta taaccactgc aaatgatgaa ttatcaaaga aaatagaacc
     3781 ttatgtaaat ccaagttctg tacgatttga cgcagtgaaa gaacttaatg attctggaat
     3841 tttttgtggc atattattga ctcctatgct tccatttttg actgataata aagatgaaat
     3901 acgagcaatt gtagaaaaag cacacaaggc taatgcaaaa tttatttatt gcatgtatgg
     3961 tgtaacaatg cgtagtggtc agagagagtt tttttatgag catttaagag atatatcacc
     4021 aaaattggta cttaaatatc agaaaacata tggtttaaac tatgtatgta ctgtacaaaa
     4081 taaagattct tgtgagaagt tgttaagaga agaatgtgca cgttatggta ttttgacgga
     4141 tatgaaagat attataaaag cgtacaagag gtcggagtca tatactcaaa taaaattttt
     4201 ttaagatagg ctttggatga gatataatag tgttgattga tgtgttgata ttatagttga
     4261 ttgttagaga ggatattata gatgaatatt agtattgata ttttaggtaa ttgttagagc
     4321 tgatattata gatgaatatt agtattgata ttctaggtaa ttgctagagt tagtattata
     4381 gatgaatatt agtattgata ctctaggtaa ttgctagagt tagtattata gatgaatatt
     4441 agtattgata ttctaggtaa ttgctagagc tgatattata atttattatt agtattgata
     4501 ttctaggtaa ttgctagagc tgatattata atttattatt agtattgata ttctaggtaa
     4561 ttgctagagt tagtattata gatgaatatt agtattgata ttctaggtaa ttgctagagc
     4621 tgatattata atttattatt agtattaata ttctagggaa ttatcactat attttaaaaa
     4681 gtaaaaatat atatcaaaat gaattaaata agtactgtaa gaagtttgtt aaattaaggt
     4741 ttgaataaag tgagggtgga gaacttatga tagaaataaa aactatagaa ataaataaaa
     4801 aaagtcgaat tgacctttta atgttagccg acccatgtga agaaatgatt gataaatatc
     4861 tcaataaagg aactatgtac gcattgtatg ataataaaga acttacttgt atagcagttg
     4921 taaatgaaat ttccaaagaa atatgtgaat taaaaaacat tgctacatat gagcattttc
     4981 aaaatatggg ttatgcctca aagatgattt atcatctttt agatgtttat agtaaaaaat
     5041 attcatcaat ggttgttggt acatctgaaa gcggagttcc tttttatgag aagtttggat
     5101 ttgtttattc acataaaatt aaaaactttt ttgtagataa ttatccagaa ccaatctttg
     5161 aaggagaatt acaatgtgtt gacatgttgt atctatcata taacttttag ataggataat
     5221 atttttaggt taatataatt aattaattca tataattatc ggaattataa tttataaatt
     5281 atgtataata agagtataat ttatttagaa gctgttatat tgtattatat tcaaataaga
     5341 tatataataa cttgtttatt ttgaattttg gaggattaat tatggattca aataataata
     5401 ctataaaatc aactgttaaa aagggtattt cttttggttc ttgtttagca atgattattt
     5461 cttatactgc atggaaatct attccatggg ctatttttca tggcttaatg agttggatat
     5521 atgtacttta ttattgggtt aagtatgcat agattaaatt aataaataag tatgtaatat
     5581 tgtaaagttt aagaaacaaa atgtaaggga gtgtctcgaa gtgaactttt agtttataag
     5641 gcactctttt ttgtattaaa taaaatatat tttcattatt taaacaatga aaaagatgag
     5701 tatctctatt ttaatacata cccttatatt cattcattta tcaacaatag ttttaaaaag
     5761 aaagctatct aaaatctatt gtaatctaag tgcttctctt taaagtctta actttagtaa
     5821 tgatatataa gtttataagg ttcttatttc aataatgcaa attttactta gaagttcaga
     5881 ctttggtatg aagaaatggg taataataaa aaagaggtgt tgatatgaaa gaaaaattag
     5941 aagaaaaatc taagattatt aaaacatcaa aagagtataa acgaactata attgaagaaa
     6001 aggacagaga atggaccaaa aaattaaatg acatacttag tagaggtgat ttttctaatg
     6061 aaaaattaga taaaatcaag gatttaattc caaaagaaat attgactagt gaaaatgttg
     6121 gagaagttgt aactgaagat gggtatgcta agcctgagta tgatgaggta tttaaatcat
     6181 tgtttacttt aaataatgat tacgatttac ttgcaaattt tataaatgat atcctcaaag
     6241 atgctccata tgctaatagg aatatcaaac agttcactca aataaaaaga ataattaagg
     6301 ttgaaaccga cccaacaatt aattacattg gtgagaaaag acctagactt gatattttgg
     6361 ctgaagatga agaacgtaac catataaata ttgagatgca aagagctctt gaagaggatt
     6421 atttggaaag agctgaatat tatcttagtc gtgtacatgg tagaaagtta gaagaaggta
     6481 aagaatataa agaaattgga aaaactgttg gaatacatat actaaatcat gtaaaatata
     6541 atcacataga agattatgta aattgcctga gattaacaat ggacgggcat ccagatattt
     6601 attctagtaa aactgcatta tattttatag aacttccaaa aattcgtaaa tccagttgta
     6661 tagcaaacag agttctaata tggggtaaac ttattgataa tccttctcat atagatatta
     6721 gaatactatc taaaacggat tatgttatta aaagagcact tgatagatta aaagaattag
     6781 gtagtaatga ggactattta ttaaatttaa agagaggtgc gtatattatg aataaaagta
     6841 gaaattttaa agaagaaatt tttcaagaag gtattgaaaa aggtattgca aaagggaaaa
     6901 gagaagagaa atttaatatc atcataaaat taaaaaataa aggatacaat ttgagtgaaa
     6961 tatgcgatat tatagatgat ttgaataaat cagaggttga aaaagtctat aatcaaaact
     7021 aatactatga ttgagatggc actagataaa tacaaagctt cctcttttaa atttaaatta
     7081 atataaaact ttgttattta aatatggtag atataaagag atatataaat aataggtaca
     7141 aagaggtgta taaataaagg agataattca aaataaaagt ttgaaccatc tccttcttat
     7201 agaaaaacaa aggggttgat ttatatatga aattttatac tatacagact ttagaatttt
     7261 ggaataacaa taaaaacaat aaatatctat caaatgatta ttcttttata ttagaagact
     7321 ttgatattcc atacaaatgg atgtatagtc aaatgacaaa tagaatatat gaatttgatg
     7381 atagtatgat atgggtttgg acgaagagac ctgatttaag atgtagtggt tatttagaaa
     7441 aaggaaaaaa aggtgtttta cttgaaatag aaataagtga agacaatgtg ttattatcag
     7501 aatttgattt atggcattta cctttaatgg atattactgt agagctttat gaagatgaac
     7561 aaattgaaaa gaaggtaagc tgggaaagaa tatttgactt agaactgtgt tcaaaattaa
     7621 atgaagttaa tatagaagat ttgacattgc aaggagtgac atctaaagtg cctctatcta
     7681 atgtaaaatt aataaaagaa tttgttgcaa aataatattt ttattgaaat ttattcaaaa
     7741 aagttatata tttataacaa gaggtgttat aaatacataa ctttttaagg gggattttat
     7801 atgtctaaac aacaaactgg tattaaatca acacttattt cagaaatatt gggaatttct
     7861 tattgtattg gagctacatt agtaaataag tattttttta aaggaagtag tattgaatat
     7921 cttcctataa ttatttgggt attagctatg ggagctcagt gggtctataa taaaaagtat
     7981 gatgatttaa ttgatgaggc atcaaaatgt atactatcaa gagttaatga tattgcaata
     8041 aaagtattgt ttttttctgt agctatagta tctatatttc ttgtaacttt ggacataaat
     8101 gtgtcaaatt taaatatagg aatgtcttta ttagtcattt tgtttattca atccttgttg
     8161 aagttaattc tatttatata ttttgacaga aaggggatat acaattaggt gtcagtatta
     8221 ctaaagacaa aaattaaatc ctatagagaa aagaacctta tgacacaagg tgaacttgca
     8281 aagtcagtag gagtaagacg tgaaactatt gtacatttag aaaatggtcg ctacaatcct
     8341 tctttaaaac tggcaatgga tattgctaag gtatttgata caactgtaga agagttgttt
     8401 gaatttattg aagaaaataa tatttaaatt tcatgtatta cttatgcatt agagaatgaa
     8461 ttaattatag gtaaaaaacc aagcttatag attagagaat aaatgactta tagatgaaaa
     8521 accaagctca t
//
LOCUS       DAEHWO010000126         7982 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEHWO010000126 DAEHWO010000000
VERSION     DAEHWO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.129"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..1395
                     /locus_tag="KNP54_003713"
     CDS             <1..1395
                     /locus_tag="KNP54_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894567.1"
                     /translation="DIRLVGGAWDNEQGLLSRIIVAGGGGGSYSPYTGGAGGGLAGGT
                     GYSANDRHRPGGTQYQGGIGRVSTENGSFGKGCSAKDSTGEGGGGGWFGGAGMNGVGA
                     GGGGSGYVLTKDSYKPTGYTPTSEYYFDNVVMESGGNTAGAYGYAKITLLQALPFLTV
                     SSYNSITATFKADHTDPTLLTKIEYFIDDILKETITTDLTTEKTINYTLEDNALHTLK
                     IVVTDSNNTTAEKVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALK
                     NIEASLNNTLVELSEKIKTSFDSSDASVQDLMNQLTQANNTISQLNSKYKYATGTAYA
                     RENSSLIACVYDPNTSHTVTETSPYWLDLNGIGFIPDIFFAECEYEPHSNAFYKYFVF
                     AIKNTFPISNNTGFVVNIAFNKEYGDESFKLRGALYTLGKRHVSMDNNGVRVPSLSTL
                     NDFRAYKWHAIKFK"
     gene            1409..1702
                     /locus_tag="KNP54_003714"
     CDS             1409..1702
                     /locus_tag="KNP54_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894568.1"
                     /translation="MNRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGN
                     IDYSKQYIESINPITKEPILKDIPIYLSEEEKRIQELENQILLNENEKVGGLL"
     gene            1702..1884
                     /locus_tag="KNP54_003715"
     CDS             1702..1884
                     /locus_tag="KNP54_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894569.1"
                     /translation="MNINNVVVRILAERILSRGLNPLKNRPFELDDVTNEDYRKAVED
                     CIIKESGVVERVETTK"
     gene            1912..3813
                     /locus_tag="KNP54_003716"
     CDS             1912..3813
                     /locus_tag="KNP54_003716"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894570.1"
                     /translation="MIYKDLLKKVNDIENLKEVDNIKCSTDTGEYTIENSKKGYLTNF
                     NVEGKTLIDLWGKTSSDFSLWKATFVDGKINILTENDIRYSNFFTINYTSYKPDTIYT
                     IIVDVDKNTLPSTSGIYIHSLGEENSVFIPNLTNIAIPGGVIGKFKYTFTTISDLNDC
                     NVVLRSVLDNDTLTSGYEISLKITILEGDYTDINIDYSNELLSVGQRDKIEFLSYQYS
                     GINIFNKNADFKDNYILQYLSGEELISEASNHKYTLDYIEIEPDTEYTFYNCSRNICW
                     YDINKNFIPASLNERIIGDKDIFYIARSPKNAKYLRVTIIKDLHDNGNKTIITKGNKY
                     DKKTIPYTLRSLPNGVKDEIVYKNDKYYLIKRCEEHTYTDIGNLNLSHVYDNTLQFMG
                     TLTPQAVVDSLDTAYVLCNNLNGKSRNDFNNNDIEGCSTTGSGDIAFKILKSKLTTQD
                     GNGFSEWIKNNPITIIYQLSKPQEIELTSLNLEQYNNQTKFICNTGIVIPDISFESTQ
                     NLGSHIEVIRNNIKNYNVRTDFPFSINFLNGWQPYLGYASSVGNYCTNNNLVTINATI
                     NGGITTAGTIIGKIPSKYAPRKGIIVIFQTTDGKYYNGIIRTNGEIEIYYNDITYRSW
                     LYLYVNYLI"
     gene            3828..4148
                     /locus_tag="KNP54_003717"
     CDS             3828..4148
                     /locus_tag="KNP54_003717"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894571.1"
                     /translation="MDIEKKIEILIEYGFENDLNNIDNYFIAEGKKIFTPVIKNGELI
                     KTGEQVYNEWIELQNNPPKPSIEEINADKITILIENQKQQDSLLVDNAYRIAMLELNT
                     NNVL"
     gene            4174..4344
                     /locus_tag="KNP54_003718"
     CDS             4174..4344
                     /locus_tag="KNP54_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894572.1"
                     /translation="MYNILKRMIEQKNYETREELQTKLDVFYAMNRIKESEYTELTNL
                     LNKEDTLVEPII"
     gene            4425..5240
                     /locus_tag="KNP54_003719"
     CDS             4425..5240
                     /locus_tag="KNP54_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0894573.1"
                     /translation="MNIKTLTIHAGHNPDNKIGSGAIGNIKESTEARNVLKELLPLAQ
                     KECKVYDCTCNNGTSQSDILNKIIAKCNSYNTDLNVSIHFNSGGGRGVEVLVYNLNDK
                     ETVEIASRICKKITETYHAKGDKDFKNRGVKEKKTLAFLRRTKAKSILVECCFVDTSD
                     TKKYNTKDMAIDIYEGIFNKSVAGKPQDNKVKYAIVYEGDVDKVIAQLMAMNYKTNEV
                     SVCDLKNYVPGHCENLYVIGGASSKIKTSERFTKLQGDDRWATLHKVLDFIGK"
     gene            5252..5869
                     /locus_tag="KNP54_003720"
     CDS             5252..5869
                     /locus_tag="KNP54_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBF0894574.1"
                     /translation="MNILDKSTATLEQVFSYLDTLKNNSNPPHFLCRAIVPIIYKEAE
                     KKGVNPVIAIAQAFVETGYFNFGRVLNPSYCNVCGLKGNKGGGDLDPTAHTRFNCWED
                     GVSAFIDHLALYAGAKGYPKYNELVGKVEYKVNGTTLDPRHFSYLHGEAKTVESLSGK
                     WCPDTNYGQNIINICNKISSMKVENNDIKLEQIKTKVKELNEILG"
     gene            5881..6132
                     /locus_tag="KNP54_003721"
     CDS             5881..6132
                     /locus_tag="KNP54_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBF0894575.1"
                     /translation="MDIMQFIPENLIMLIGGLYILGTFIKESNIKNKYIPFILLVIAM
                     ISSCLFMKELSIEAVFEGILCWGASIGINQIQVQNRKDK"
     gene            6133..6444
                     /locus_tag="KNP54_003722"
     CDS             6133..6444
                     /locus_tag="KNP54_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894576.1"
                     /translation="MLSKEMVELLSQYGYTAILLMVLMLWLGKYLEKNRQLEQDDRKK
                     ERAYFSREIKEQRTLFGNTIDKFDDKLDKFAEALNTNNSRLERVETDITKIKDKLETR
                     D"
     gene            6478..7413
                     /locus_tag="KNP54_003723"
     CDS             6478..7413
                     /locus_tag="KNP54_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBF0894577.1"
                     /translation="MAKQRSKRISINGEPNPENIKLWKQYKRAKQIAGKSEKTIYNYE
                     CDIMQFFKFLNIECFDTLLTDINEEEIEAYIGYCMEQGNNEKRIRRRISSISSLLSFL
                     KKKRKITDNWCEMIERPGTGEEVQKRTFLTEEQLRKLKEKLSEQDNLQLEVYINLGLA
                     TMARSNEISQFRWDNIDLDNRWIHGITAKGGVSRDFRFSEEVQHLLIEWKDYLSQNNI
                     DYPYIFFTRYGGKYNQVNSNVLSSWVKKAFRLIGIEGGYNHDLRHSMSNLLKDRGVPI
                     TTVSKLLGHSGVDVTINHYTIENKNKLAEEYDKFM"
BASE COUNT         3288 a          864 c         1383 g         2447 t
ORIGIN      
        1 gatataaggc tcgttggtgg tgcttgggat aatgagcaag gtttgctatc tcgtataatt
       61 gtcgcaggtg gtggcggtgg ttcatattct ccttatactg gtggtgcagg aggaggatta
      121 gcaggaggta ctgggtatag tgctaacgac agacatcgtc ccggcggtac tcaatatcaa
      181 ggtggtattg gtcgtgtaag cacagaaaac ggaagttttg gaaaagggtg ttctgctaaa
      241 gattcaactg gcgaaggcgg tggaggtggc tggtttggtg gtgcaggaat gaatggtgtg
      301 ggagcaggtg gaggtggaag tggctacgta ttaactaaag atagttataa gcctactggc
      361 tacacaccaa catctgaata ttattttgat aatgttgtta tggaatctgg tggaaatact
      421 gctggtgctt atggttatgc taaaataaca ttactacaag cattaccatt tttaacagta
      481 tcttcttata attccattac agctacattt aaagctgacc acacagaccc tacactatta
      541 actaaaatag aatactttat agatgatata ctaaaagaaa ctataacaac agatttaaca
      601 acagagaaaa caattaacta cacattagaa gataatgcac tacacacact taaaatagtt
      661 gttacagaca gtaataatac tacagcagaa aaagtattaa gtataagtaa gaatataatg
      721 ccactacccg aaaatgtaaa tttaaatgat atatcaacaa aattagttga ggttaatgca
      781 ggatttaaag ttgggaaaac aagtattata aatactttag cattaaagaa tatagaagca
      841 agtttaaata atacacttgt tgagttgtca gagaaaataa aaacaagttt tgatagttca
      901 gacgctagtg tgcaggattt gatgaaccag ttaacacaag ctaataatac tatatcacag
      961 ttaaattcta agtataaata tgcaacagga actgcttatg ctagagaaaa ttcatcctta
     1021 attgcatgtg tatatgaccc taatacttct catactgtta cagaaacgag cccttattgg
     1081 cttgatttaa atggaattgg atttattcct gatatatttt ttgctgaatg tgaatatgaa
     1141 ccacattcga atgcttttta taagtatttt gtttttgcaa ttaaaaatac ttttcccatt
     1201 tctaataata ctgggtttgt agttaatatt gcttttaaca aggaatatgg tgatgaatct
     1261 tttaaattac gaggagcttt atataccctt ggcaaaagac atgtttccat ggataataat
     1321 ggagttagag taccttcact aagcactcta aatgatttta gagcatataa atggcatgcg
     1381 ataaaattta aataaatgag gtgataaaat gaatagagca aatagaataa tttacgacca
     1441 aactggtaaa atattactcc aaacaggaga agcaacagga gatatattag agcatgatac
     1501 aataacagaa ttacattata ttgatgttga atatggaaat atagactata gtaaacagta
     1561 tatagaatct ataaatccaa taacaaaaga acctatttta aaagatattc caatctattt
     1621 aagcgaagaa gaaaagagaa tacaagagtt agaaaatcaa atattactaa atgaaaatga
     1681 aaaagtagga gggctattat aatgaatata aataatgttg tagtaagaat attagcagag
     1741 aggattttaa gtagaggatt gaatccttta aaaaatagac cttttgaatt agatgatgta
     1801 actaacgagg attatagaaa agcagtagaa gattgtataa ttaaagaaag tggagtagta
     1861 gaaagagtag aaactacaaa ataggggttt tgtgaagaga ggtgttttaa tttgatatat
     1921 aaagatttac ttaaaaaggt caatgatata gaaaatctca aggaggttga caatataaaa
     1981 tgtagtactg atacaggaga atatactata gaaaatagta aaaagggcta tttaactaat
     2041 tttaatgtag aaggaaagac attaattgat ttatggggaa aaactagttc agatttttct
     2101 ttatggaaag caacttttgt ggatggaaaa ataaatatac taacagaaaa tgatataaga
     2161 tattctaatt tttttacaat caattacact tcatataaac cagataccat atatacaatc
     2221 atagttgatg ttgataaaaa cactttaccg agtacaagtg gaatatatat tcatagctta
     2281 ggcgaagaaa attcagtatt tattcctaat ctgacaaata tagctatacc aggaggagta
     2341 attggtaaat ttaaatatac atttacaaca atatcagact taaatgattg taatgttgtt
     2401 ttaaggagtg ttttagataa cgatacactt acatctggtt atgaaataag tttgaaaatt
     2461 accatattag aaggagatta tacagatatt aatatagatt actctaatga actattaagt
     2521 gttgggcaaa gagataaaat agaattttta agttatcaat atagtggaat taatatcttt
     2581 aataagaatg ccgattttaa agataattat attttacaat atcttagtgg agaggaactt
     2641 atttctgaag ctagtaatca taaatatacc ctagactata tagaaataga accagataca
     2701 gagtatactt tttataattg cagtagaaat atttgttggt atgatataaa taaaaatttt
     2761 ataccagcat cattaaacga aagaataata ggagataaag atatttttta tattgctaga
     2821 agccctaaaa atgcaaagta tctaagagtt actataataa aagatttaca tgataatggg
     2881 aataaaacaa ttataactaa aggaaataaa tatgataaaa agacaattcc atatacatta
     2941 agaagtttac caaatggagt aaaagatgaa atagtttata aaaatgataa atattactta
     3001 ataaaaagat gtgaggaaca tacttatact gatattggaa atcttaattt atcacatgta
     3061 tatgataata ctctgcaatt tatgggaaca ttaactcctc aagctgttgt agatagttta
     3121 gacacagcat atgttttatg taataattta aatgggaaaa gtagaaatga ttttaacaat
     3181 aatgacatag agggatgctc aactactggt agtggtgata tagcatttaa aatattaaaa
     3241 agtaaactta ctacacaaga tggaaatggg tttagtgaat ggataaaaaa taatccaata
     3301 actatcatct atcaactttc aaaaccacaa gaaattgaat taacatcact aaatttagaa
     3361 caatataata atcaaactaa atttatttgc aacacaggta ttgtgatacc agacattagt
     3421 tttgaaagta cacaaaattt aggaagtcat atagaagtta tcagaaataa tataaaaaat
     3481 tacaatgtta gaactgattt tccattttca ataaactttc ttaatgggtg gcagccatat
     3541 cttggatatg ctagttctgt tggaaactat tgcacaaata ataaccttgt aacaattaat
     3601 gcaactatta atggaggtat tacaacggca ggtactatca ttggaaagat accttcaaaa
     3661 tatgcacctc gtaaaggcat aatagtaata tttcaaacaa cagatggaaa gtattataac
     3721 ggaatcatcc gtacaaatgg agaaattgag atatattata atgatataac ttatcgtagt
     3781 tggttgtatt tatatgtaaa ctatttaatt tagaaaggaa aaataagatg gatatagaaa
     3841 agaaaataga aattttaata gaatatggat ttgagaatga tttaaataat atagataatt
     3901 actttattgc agagggtaaa aaaatattta ctccagtgat aaaaaacgga gagctaatta
     3961 aaacaggaga acaggtttat aatgagtgga tagaattaca aaataatcca cctaaaccaa
     4021 gcatagagga aataaatgcg gataaaatta caattttaat agaaaatcaa aaacagcaag
     4081 acagtttatt agtagataat gcttatagaa ttgctatgtt agagcttaac acaaataacg
     4141 tgttataaaa ttataaaaaa tggagggaac aacatgtata atattttaaa aagaatgatt
     4201 gaacaaaaga attatgaaac tagagaagaa ttgcaaacta agttagatgt attttacgct
     4261 atgaacagga taaaggaaag tgaatacaca gagttaacaa atttattaaa taaagaagat
     4321 acactagtag aacctattat ctaaagtata aaggttcttt ttttatgtca attttagagg
     4381 attgattaat ttcaattctc ttttaattaa aaggagtggt aattttgaat ataaaaacat
     4441 taacaattca tgcaggacat aatccagata ataagatagg ttctggagca ataggaaata
     4501 taaaggaatc tacagaagca agaaatgtac taaaagagtt attaccttta gctcaaaagg
     4561 aatgtaaagt ttatgactgt acttgtaaca atggaacttc tcaaagtgat atattgaata
     4621 aaattatagc taaatgtaat tcatataata ctgatctaaa tgtaagtatc catttcaaca
     4681 gtggtggtgg tcgaggagta gaagttttag tttataattt aaatgacaaa gaaactgttg
     4741 aaatagcatc aagaatatgt aaaaaaataa ctgaaactta tcatgcaaaa ggtgataaag
     4801 attttaaaaa tcgtggagtt aaagaaaaga aaactctagc atttttaaga agaacgaagg
     4861 caaagtcaat tttagttgag tgctgttttg tagacacatc tgacactaaa aaatataata
     4921 ctaaagatat ggctatagat atttatgaag gaatatttaa taagtctgta gctggtaaac
     4981 cacaagataa caaagtgaaa tatgcaatag tttatgaggg tgatgtagat aaagttatag
     5041 cccaattaat ggccatgaat tataagacta atgaagtctc tgtgtgtgat ttgaaaaatt
     5101 atgttcctgg acattgtgaa aacctatatg tgattggtgg agcatccagt aaaattaaaa
     5161 ctagcgagag attcactaag ttacagggcg atgatagatg ggctacactt cataaagtgt
     5221 tagattttat aggcaagtag gaggtaatga attgaatata ttagataaat caacagctac
     5281 attagaacaa gtcttttcgt atttagacac attaaaaaat aactctaatc caccacattt
     5341 tttatgcaga gctatagtac caattatata taaagaagca gagaaaaaag gtgtaaatcc
     5401 agttattgca attgctcaag catttgtaga aactggatat tttaattttg gtagagtttt
     5461 aaatccttct tattgcaatg tgtgtggtct taaaggaaat aaaggtggag gagatttaga
     5521 cccaacagct catacaagat ttaattgttg ggaggatgga gtatcagcat ttattgacca
     5581 tctagcatta tatgctggag ctaagggata tccaaaatac aatgaattag ttggtaaagt
     5641 tgaatataaa gtcaatggaa ctacattaga ccctagacat ttttcatatc tacatggaga
     5701 agctaaaaca gttgaaagct tatcaggtaa atggtgtcca gatacaaact atggtcaaaa
     5761 cataataaat atatgcaata agataagttc aatgaaggta gaaaacaatg atataaaact
     5821 agagcaaata aaaactaaag taaaagaatt aaatgagatt cttggatagg aggaaatcac
     5881 atggatataa tgcaatttat acctgaaaat ttaataatgt taataggtgg gctttacata
     5941 ttaggaacat ttataaaaga atctaatatt aaaaataaat acataccttt tatattgtta
     6001 gttatagcaa tgataagtag ttgtttgttt atgaaagagc tgtcaataga agctgtcttt
     6061 gaaggtattt tatgttgggg tgcatctata ggaataaatc aaatacaagt gcaaaacaga
     6121 aaggataagt agatgttatc aaaagaaatg gttgaattac taagtcaata tggatataca
     6181 gctatacttt taatggtact gatgttatgg cttggaaaat atttagagaa aaatagacaa
     6241 ctagaacaag atgatagaaa aaaggaaaga gcttattttt caagagaaat taaagagcag
     6301 agaactttat ttggtaatac aatagataag tttgatgata aattagataa atttgctgaa
     6361 gcattaaata ctaataacag tagacttgaa agagttgaaa cagacataac aaaaattaaa
     6421 gataaattag agactagaga ttaatttctc tagtcttttt ataaggaagt gaagtatttg
     6481 gcaaaacaac gcagtaaaag aataagcata aatggagaac caaatccaga gaatattaaa
     6541 ttatggaagc aatacaaaag agcaaaacaa atagctggga aaagtgaaaa aacaatatat
     6601 aattatgaat gtgatataat gcaatttttt aagtttttaa atatagaatg ttttgataca
     6661 ttactaactg atataaatga agaagaaata gaagcttata taggttattg tatggaacag
     6721 ggaaataatg aaaaaagaat tagacgtaga ataagttcaa tttcatcatt gctatcattt
     6781 ttaaagaaga agaggaaaat tactgacaac tggtgtgaaa tgatagaaag accaggaaca
     6841 ggcgaagaag ttcagaaaag aactttttta actgaagaac agttacgcaa attaaaagaa
     6901 aagctttcag agcaagacaa tttacagtta gaagtttata taaatttagg attggctaca
     6961 atggctagaa gtaatgagat aagtcaattt agatgggaca atatagattt agataataga
     7021 tggattcatg gtattacagc caaaggtgga gtttcaagag attttagatt ttcagaagaa
     7081 gtccagcatc tattaataga atggaaggat tatctatctc aaaataatat agattatccg
     7141 tatatattct ttacaagata tggaggcaaa tacaatcaag tcaattcaaa tgtcttaagt
     7201 tcatgggtta aaaaagcttt caggttaatt ggtatagaag gtggatataa tcatgacctt
     7261 agacatagta tgtctaatct tttaaaagac agaggagttc caataactac agtttcaaaa
     7321 ttgcttggcc acagtggggt tgatgtaact ataaatcact acacaataga aaataaaaat
     7381 aaattagctg aggaatatga taagtttatg taaattgaaa ggaagtggta tcatggcatg
     7441 taaaggtcgt aaaaaaggta agaaaaagag atagataaat aataaagccc tctagggatt
     7501 actcttaatt gagttttctt tagagggctt tattttttta tatatgttta tataaattta
     7561 taattatata taatgctaaa ccacttaaaa tacttttcaa aaaaaatgat tttatttgaa
     7621 attttttaaa taaaacatca gaaacataaa atacagcaca tgctataaaa aaatataaaa
     7681 attcattatt aattcctgcc aatctaatat gtatgatagt aaataatatt ataataatca
     7741 aaaacgtatc tataaaattt ttgtgttttc attcaatata ttaaacttat tttaattagg
     7801 tatctatctc aagtctatcc taatagtata gaatatgtaa gaaattatta attaataatt
     7861 cttaactatc aataaactaa tcttaattat ttattaatat ttcttaatta tatatatgaa
     7921 tgcataacta taataaaagt attaaaaaac aatctaaaaa tcgatttaaa taaatattta
     7981 tc
//
LOCUS       DAEHWO010000127         7720 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEHWO010000127 DAEHWO010000000
VERSION     DAEHWO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.130"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            18..1076
                     /locus_tag="KNP54_003724"
     CDS             18..1076
                     /locus_tag="KNP54_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBF0894578.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRSIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1180..2364
                     /locus_tag="KNP54_003725"
     CDS             1180..2364
                     /locus_tag="KNP54_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBF0894579.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMIVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2571..3284
                     /gene="rpsB"
                     /locus_tag="KNP54_003726"
     CDS             2571..3284
                     /gene="rpsB"
                     /locus_tag="KNP54_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBF0894580.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3363..4274
                     /locus_tag="KNP54_003727"
     CDS             3363..4274
                     /locus_tag="KNP54_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBF0894581.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4359..5063
                     /locus_tag="KNP54_003728"
     CDS             4359..5063
                     /locus_tag="KNP54_003728"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBF0894582.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5089..5646
                     /gene="frr"
                     /locus_tag="KNP54_003729"
     CDS             5089..5646
                     /gene="frr"
                     /locus_tag="KNP54_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBF0894583.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDALLSKKEKDIMEV"
     gene            5649..5852
                     /locus_tag="KNP54_003730"
     CDS             5649..5852
                     /locus_tag="KNP54_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894584.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5881..6615
                     /locus_tag="KNP54_003731"
     CDS             5881..6615
                     /locus_tag="KNP54_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBF0894585.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6628..7407
                     /locus_tag="KNP54_003732"
     CDS             6628..7407
                     /locus_tag="KNP54_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBF0894586.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3176 a          785 c         1458 g         2301 t
ORIGIN      
        1 ctggaggata tatatttatg aattgtaaat ggatatctaa aatagatgag agaaaaaaat
       61 gtcatagaga agcagattct tctggatatt gtatctttca taaagaaaat aagtctgatg
      121 aagaaataca gttgatgatg gatactattc ataaagaaga gataagtgaa tttaatggat
      181 ttgtttttga aaatgaattt aatgcggaag aaatattaac ttacaattat aaaatactgg
      241 atttttctga atccatattt aaacaaaaag caaattttaa aaaatatatt tttaaaaaga
      301 atattatttt taactataca gaatttagag ataaagtttt atttaatggt tgtgtattct
      361 tagaaaactg tgattttaat agaagcatat ttagtaaaaa ctatataaat gaccgtatat
      421 ttgaaaaagt gaaatttaaa ggacctgatt tggtagttaa taaagtagaa aattttccaa
      481 gaatggatgg aataattttt agcatgtgta caaaatttgt gttaaagaat gttgaatatg
      541 gaaaaagtga gtatgagcat ggcaagataa attatagaat agctagaaat caagcaacaa
      601 aaattggaga atatgagatg ataggatttt actattataa ggaaagaatt tatagtagta
      661 aaataatgaa acgttctaat tatcctactt tcagtgatta tttagttgaa aaattttttg
      721 accaaatagc acgttacaca acaggttatg gagaaaagcc atggaatata ttattagtta
      781 ttatagcaat aataagtgtt tttgctttat tatacttatt tgtaggcata gaaagttcaa
      841 atagcacact tgtagcttta gatataaata atataggtga ttactcacta agtgagattt
      901 tcaaaatgta tatggattta tggtatttta gcatggctac atttagtaca gtaggatatg
      961 gagatatggt tgctacaagt ttgattggga aagcattggc aggtatagaa gtattttttg
     1021 gagttacaat aggagcaatt tgggcatctg tgattattaa aagaatgata aggtaatatt
     1081 tgtgtaaata tggataggta ttaattacta gatataaatt ggactaaata gggaaaattt
     1141 aaatataaat atacttaata atccaagaag gtgaaaaatt tgaaaaatgc actaaaaaaa
     1201 attatatcat tagccatgat tctagttttt ataataccaa attattcata tgcagatgat
     1261 aaatctgtag acaagtattc aaaaacatct atacttatag accaagaaac aggtagagtt
     1321 ttatatagta aagaacctga tatgaaggta ccattagcta gtttaagtaa gatgatgact
     1381 tttttacttg caatagaagc tattgaaaat aaagaagtaa aagaaactga taaagtaaaa
     1441 atagacaaat ctattgcatc agtaaaaggg tcaagttata aacttaaaga tggtgaagaa
     1501 gtgccactta tagagcttat gagaggtctt atgattgtat caggaaatga tgcggcaatt
     1561 gctatagcaa aacatatttg taaaacgaaa gaagcatttg tagatagaat gaataaaaaa
     1621 gcaaaagaaa taggaatgag taatacacat tttctaaatc caaatggtct tccaatatac
     1681 gatttaagca accccaaaaa accagcaaaa gaaaatatct ctactgcaaa agatatagct
     1741 attcttggaa aatacatgtt tgaccattat gaaaaacaag taacagctat aactgatatg
     1801 gagacatata caaattcaga tagaagtttt gaaaaaagca atacaaatgc attattaaga
     1861 attataccag aagtagatgg tataaaaact ggatatactg gcaatgctgg atattgctta
     1921 tcattttcta tgattgtaaa taaaaatgat aaaaatgaga aaaaacgtag agtaataggg
     1981 gttgtattag gtactaacca taaaaataaa agaacctctg cttcattagc tctactgaaa
     2041 tatggaaaag aaaatttcaa tatgaaaaaa gtaattgata aagatagctt tattggtaag
     2101 aaatatataa aaggaatgaa agagttagag gttacattaa aagcaaaaga tgaactttat
     2161 acaatattaa aagatgatga aagtataaaa tcagaagtta agattaaaaa tatagagtac
     2221 cctgttaaaa aaggtgatac tatgggtatt ataaaatatt atactaattc aggtgactta
     2281 cttggaagtg tagatatagt aagtaataat agtatagata acgtatcatt aaaaacaaaa
     2341 ttaaaaatga aatttgcaaa ttaaattcaa aaaatggtat aaaatacaca aaaaaatata
     2401 aaaatagaaa atatggaaaa aatattgtta tttcttcacc tctgtgatat actactagag
     2461 gtgaaaaaat aaaataaatc acacacagca ttgggatcct taaaaggtgc ctattacatg
     2521 gttttttagg gagaagatca agctggaggt ataaaaccag gaggtaagat atgtcagtaa
     2581 tatcaatgaa acaattatta gaagcaggtg ttcactttgg tcaccaaaca agaagatgga
     2641 accctaaaat ggctaagtat atattcacag agagaaatgg aatatatata atcgacttac
     2701 aaaaaacagt taaaaaagtt gaagaagctt acaagttcac taaagaagta gctgaaacag
     2761 gaaagccaat cttattcgta ggaactaaaa aacaagctca agatgcgata aaagatgaag
     2821 ctgaaagatg tggaatgtac tttgttaatg aaagatggtt aggtggaatg ttaacaaacc
     2881 acaaaactat aaaaacaaga ataaataaat taagagaatt agaaaaaatg gaagaagaag
     2941 gcgtatttaa tgttcttcct aaaaaagaag ttataaaatt aagagctgaa aaagaaaaac
     3001 tagaaaaata cttaggtgga ataaaagaca tgcctgaatt accaggtgca atgttcgtag
     3061 ttgacccaag aaaagaaaac atagctattc aagaagctca tagattaggt ataccagtag
     3121 ttggtatagt tgatactaac tgtgacccag aacaattaga ctttgctata ccaggaaatg
     3181 atgacgctat aagagccgta aaattaataa ctggtgctat ggcaacagct gtaattgaag
     3241 gtagacaagg tgctgaggaa gaagtagctg aagaccaaga ataataattt gacaattaaa
     3301 tggtaagggt cgcccttacc atttataata tggaatagaa taagtaggag gaaacttaaa
     3361 aaatggctaa tataactgct caaatggtaa aagagttaag agaaagtaca ggcgcaggaa
     3421 tgatggactg caagaaagct ttacaagaag ctgaaggaaa catggaaaaa gcagtagatt
     3481 tattaagaga aaaaggatta tcaaaagctg ctaaaaaagc tggtagagtt gctgctgaag
     3541 gtctagttgc aatagaaatg aatgatgata atacagttgc ttctatggta gaagttaact
     3601 cagagacaga tttcgttgct aaaaacgaag acttcaaagt gttcgttaaa gatgctgctt
     3661 gtatggcatt agctactgat aaagaagata tagcttcttt attaggtgaa actcataaag
     3721 agggaataac tttacaagaa gttttaaata atagagttgc aaaaataggt gagaaattag
     3781 actttagaag atttgctaaa gttgtaacta atggacaagt tgctggatac attcacggtg
     3841 gtggaaaaat aggtgttctt gttgaaatgg aaacagaagc tagagatgct aaagttttag
     3901 aattaggtaa agatgtagct atgcaagttg ctgctatgaa tcctaagtat gtttcaagag
     3961 atgaagtaga tgctgaatac atagcacatg aaacagaagt attaactcaa caagctttaa
     4021 atgaaggaaa accagctaat atagttgaaa aaatggttaa aggaagatta gaaaaagaat
     4081 taaaagaggt ttgtttatta gagcaaactt tcgttaaaaa tccagatata actgttaaac
     4141 aattagttgc tgatgttgct aaggcagtag gttctgatat aaaagttgtt aaagttgtga
     4201 gattcgaagt tggtgaaggt atacaaaaga gagaagaaaa ctttgcagaa gaagttgcta
     4261 agcaacttaa gtaataacca aagagagaac acgcaggtgt tctctttttt aaaaaataga
     4321 aaaaattgga tatgaaggat tgaaatagga ggtttctgat ggataaacca atgtacaaaa
     4381 gggtattgtt aaaattaagt ggagaagcat tagcaggaga aagaggtttt ggtataaata
     4441 atgatgtagt taatgatatt gctattgcta taaaaaaaat acaagaaata ggtgttgaag
     4501 tagctgtagt agtaggtgga ggaaacttct ggagaggcag aaccagtgaa ggaatggaca
     4561 gaactactgc tgactatata ggaatgttag ctacagttat gaatgcaatg gcgctacagg
     4621 atgcactaga aaatatagat gttgctacaa gagttcaaac tgctatagac atgagacaaa
     4681 ttgcagaacc atatataaga agaagagcag ttagacactt agaaaaggaa agagttgtta
     4741 tatttggtgc aggaacagga aacccttact ttacaacaga tacaactgct gctttacgtg
     4801 ctgctgagat ggaagcagaa gttatattgt tagctaaaaa tgttgatgca gtatatgaca
     4861 aggatccaaa agtacatgca gatgctaaga aatttacaga attaagttac atggaagtta
     4921 tacagaaaga attaaaagta atggattcta cagctacatc tttatgtatg gataataaaa
     4981 ttccaataaa ggtatttgag cttacaacag agaatataat aagagcagta aaaggcgaaa
     5041 atataggaac tactgtaaaa taatgaagaa tgaaggagga gtaaaattat gaaactggaa
     5101 atacataagc aattagaaga gaaaatgaat gggacaattg atgctttaaa gtttgaattt
     5161 ggaactataa gagcaggaag agctaatgca caaatgctag acaaaataag agttgattat
     5221 tatggaactc caactccaat aaatcaaata ggtgctatat ctgtaccaga accaagaata
     5281 ttaatgatat ctccttggga taaatctgct atgcatgaaa tagaaaaagc gatagctaac
     5341 tcagacttag gattaaatcc atcaaatgat ggtgaggtta taagactttc tgtacctgct
     5401 ttaacagaag aaagaagaaa agaattagct aaaaaagcta gtaaagctgc agaagaattt
     5461 aaagttagaa taagaaatga aagaagagac gccaatgaga aaattaaaaa gatggaaaaa
     5521 ggcggagaat taactgaaga tgaattaaaa aaagcacaag atgaagttca aaaaatgact
     5581 gataaattta taaaagaaat agatgcatta ttatctaaaa aagaaaagga cataatggag
     5641 gtataatatt gaaaaaatat tataaccttt taggtcttca tgtagatgag gtaaaacaat
     5701 attttgatga gcaaaatata aattataccg taaaatctat tgaaggtaaa aaggataaag
     5761 aaaaacttgt agttcctaga gttataaaaa tatctgagat aggtgatagt gtagaactga
     5821 taatcacata cttttctgac tccttagttt aaggagtcag aacaatattg gaggcaaaat
     5881 atgaataaca acattatata tgatatagac ttaaataaca tacctactca tattgctatt
     5941 ataatggatg gaaatggaag atgggcaaaa gctagatttc ttccaagaac tgcaggacat
     6001 aaggctggag tagaaactat aagagatata gtaaaagaat gctcaaaatt aggtgttaag
     6061 cacttaacat tatatgcatt ttcaacagaa aactggaaaa gaccgaaact tgaagttgac
     6121 acacttatga acttattatc tacatactta agaaatgaaa tagctgaact tcaccaaaac
     6181 aatgtaaaag taactgctat aggagatata agtgctttac caaaaacttg tataagagaa
     6241 ttaaactcag ctaaggaact gacaaaaaac aatacaggag ttaacttaaa tttagcatta
     6301 aactacggaa gtagagcaga tataaaaaat gctcttatag atatagtaaa aaattgtgaa
     6361 agtggtaaaa tagatataaa caatattgat gaagatatta taaaaaacta tttaagcaca
     6421 aagtctatac cagatccaga cttggtaata agaacaagtg gtgaacaaag attgagtaac
     6481 tttttacttt gggaagttgc ttattctgag ttttacttta ctgatataca ttggcctgat
     6541 tttaaaaaag aagaactaca gaaggctata tacgtatatc aaagaaggga tagaagattt
     6601 ggaggactta agtaaggaga ttattttatg cttacaagaa ttattgcttc actagctctg
     6661 gttccattat ttctatttgt tgtatatgga ggtattcctc tatatatagc tgagacagca
     6721 atagtttata ttgcattgca tgagttttat aaggcattta aaataaaaga tgtacatcca
     6781 atattcatta taggatattt attttctatt tatttagctg taaaaaatat ttttaattta
     6841 ccattagaat atacttatgc agtaattttt attttatttt tagcaagtat aatttatatg
     6901 ttgatgggca aaaacaatgt tatagatgtt tcgattacgt ttttaggagt tttttatata
     6961 ggagtatttt tagattttat aattataact ataaatggat ttgaaaaagg tagtatatat
     7021 gtatggctta tatttgtgat atcttttatg acagatatat ttgcatattt tagtggttat
     7081 ttacttggaa aacataagct aattcctaaa gttagtccta aaaagactat agaaggagct
     7141 attggaggaa taataggaag tacactttgt tgtattttat ttggatattt atttggcatt
     7201 gatttgcttc aattagcgat aataggaagt ataggaagtg taatagctca attaggagat
     7261 ttatttgcat cttctataaa gagatatgta gggataaagg attatggaaa gataatacct
     7321 ggtcatgggg gtatattaga tagatttgat agtgttatat tagttgcacc ttttgtatat
     7381 agtgcgatta aattttttat tagataaaga ttggttggat ttaaaagagc aatctataat
     7441 tgctagtaat gaaaatagct atgtaacttt taaatgcaga gatattctgc agttattagt
     7501 tacatggcta ttttcattgt tcaaaaattt agaagacctt ggggaattgt ataagaatag
     7561 gtattacttt ataatagtat actatatttg tagtgagtat attttttata ctgtaactat
     7621 cattaaaaaa tatttttttg tttaataatt tcgatatttt tagctttatt atatatttat
     7681 aatatatatg tataaatgta actaatttat tatccattta
//
LOCUS       DAEHWO010000128         7430 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEHWO010000128 DAEHWO010000000
VERSION     DAEHWO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.131"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            61..1038
                     /locus_tag="KNP54_003733"
     CDS             61..1038
                     /locus_tag="KNP54_003733"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBF0894587.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            1031..1999
                     /locus_tag="KNP54_003734"
     CDS             1031..1999
                     /locus_tag="KNP54_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBF0894588.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            2182..2772
                     /locus_tag="KNP54_003735"
     CDS             2182..2772
                     /locus_tag="KNP54_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBF0894589.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTATSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            2791..3561
                     /locus_tag="KNP54_003736"
     CDS             2791..3561
                     /locus_tag="KNP54_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBF0894590.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            3698..4666
                     /gene="dusB"
                     /locus_tag="KNP54_003737"
     CDS             3698..4666
                     /gene="dusB"
                     /locus_tag="KNP54_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBF0894591.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRATEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            4775..5254
                     /gene="greA"
                     /locus_tag="KNP54_003738"
     CDS             4775..5254
                     /gene="greA"
                     /locus_tag="KNP54_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBF0894592.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            5269..6798
                     /gene="lysS"
                     /locus_tag="KNP54_003739"
     CDS             5269..6798
                     /gene="lysS"
                     /locus_tag="KNP54_003739"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBF0894593.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            7107..7301
                     /locus_tag="KNP54_003740"
     CDS             7107..7301
                     /locus_tag="KNP54_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894594.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
BASE COUNT         2959 a          755 c         1506 g         2210 t
ORIGIN      
        1 tgtataatta tttattagaa gaaaataagt catgaaatta tgtcatatta gaggtgaaat
       61 atgagagata aaataataga gattatatta aataataaat ctgaatttat ttcaggagaa
      121 gaattatcaa aacaattagg ggtgtcacgt gcagctatat ggaaacatat gaaagcctta
      181 aaagaagagg gatataatat agaatctgta aataaaaaag ggtatcgatt agcggaaaat
      241 ccaactgatt tattaagccc acagaatatt tactataaat tagatacaga gtttattgga
      301 aaaaatattg aacatcttga cactatagat tcaacaaatg aacatgctaa aaggatagct
      361 ataaatagtg tagatgggac tgtgatttta agtgaacatc aagatatggg gaaaggacga
      421 ttgggaagaa gatgggattc aaaacctcat gaaggaatct ggatgagtat tatattaaaa
      481 ccagatatgg aaccattcaa agccccattt ataactttaa tagcaggagc aagtgtaacg
      541 aaagctttaa acaatctagg agcaaataca ttaataaaat ggccaaatga tgttatttta
      601 aatggaaaaa aaatatgtgg tatattaaca gagttatctg ctgaaattga aagaacaaat
      661 tatgttgttc ttggaattgg aataaatgtt aaaataatgg attttgaaca agaaatagct
      721 gacaaagcca catcattgta taaagaagga tatatgttat ccagagtaga tattgttagg
      781 aatgtattaa ctgaatttga aaaattatat ttagattata ctgtaaataa ttccaaagaa
      841 aaaaccttaa aaatatgtag agattattct gcaattatag ataaaaatat atatgtatta
      901 aaaggagata atagagaact agtgaaatgt ttagacataa atgaagaggg aaatttatta
      961 gttcaaagaa gtgatggaag tataaaagaa attatttcag gtgaagtttc tataagagga
     1021 gaaaaaggat atgtataata atattttgga tatagaaggc ttaaaggttg ggcaggttga
     1081 ggatagaaat ggtcttactg ggtgcacagt agtaatatgt gaagaaggag ctacttgcgg
     1141 tgttgatgta aggggctctg ctccaggtac tagagaaacc gatttattag accctgtaaa
     1201 tatggttcaa aaagttcatg cagtagtttt ggctggaggt tctgcatatg gtcttgaatc
     1261 cacttgtggt gtaagtagat acttagaaga aaaaggaatt ggctttgatg taggtgtagg
     1321 taaagtgcct atagttgtag gagcagtttt atttgattta ggagtaggga gctttaaatg
     1381 tagaccagat ttaaagatgg gttatagagc ttgtgaagtt gcaaatactg atattttaaa
     1441 tcaaggaaat tatggagcag gttgtggagc cactgttgga aagataagag gtcaggaata
     1501 tgctatgaaa ggcggaatag gtagctattc tataaaatta gataatggtc taattgtatc
     1561 tgcattaatt gctgtaaatg ctcttggaga tgtttatgaa aatggtaagg ttatagctgg
     1621 tgctttaaat gataaaaaga cagaaacaat tgatacatat aaattaatga aacaaggtga
     1681 aagtaaaggt ggatttagtg tagataatac tacaattggg ataattgcaa caaatgctaa
     1741 gttaaccaaa gctggatgta aaaagatatc tcaaatggga catgatggat atgctaagtc
     1801 tatttttcct atccatacac ctcatgatgg agatacaata ttcacaatat caacaggaga
     1861 aatagaagca gatataacat tagtaggttc attggctgta gaggttgtgg aaaaaagtat
     1921 aataaatgca gtaaaaaaag cggatagtgt agaaaatata atggcatata aagatatagt
     1981 aaaaaaacga gaaatatgat gaaattagca tatttttctt gtcaaattgt tgacaatggc
     2041 aactcatctt gataaaatta ttcttgttag agcgggcatc ctacaatggt agcttgactc
     2101 atagttataa gaaaaaacga aaaaaattaa aaaattaagt agtccggcat cttaatgagc
     2161 tggaacggag gtgtattttt tatgatgaac acaagtgcat cagtaagaaa agtaaatgta
     2221 agaaagatga ctataatagg agtactatca gctatttcta ttatgctatc tatgactcca
     2281 ttgggattta ttccagttgg acctacaaaa gcaactataa tgcacatacc agttattatt
     2341 ggagctatta tggaaggacc aatagttggg gcagcaatag gatttatatt tgggatatca
     2401 agtctcttaa atgctataac aaacccaaca gcaacatctt ttgtttttat aaatccatta
     2461 gtttcaatat taccaagagt tatgataggt gtattagctt attatgtata tcagttaata
     2521 attaaggcta caaataaggt atacatatca ggtttaatta caggggcaat aggttctctg
     2581 ttaaatacag ctggagtttt aggaatgata tatgtcttat atgctgacaa gtatcttcat
     2641 gcaatgggta aaagtggttc agcaggaaaa gtaataatgg ctcttgccgc agcaaatggg
     2701 gtgccagaag caatagtagg ggctttagta gtagctgctg ttgccactgt acttaagaaa
     2761 agcaaaaaat agaaagaagg ttaatgacat atgcttctag tatttgatgt tggaaatact
     2821 aatatggttt taggtatata taaaggtgac aaattagtta attactggag aattaaaaca
     2881 gatagggaaa aaacgtctga tgaatatgga atcctgataa gtaacctatt tgattatgat
     2941 aatgtgaata taagtgatat tgatgatgtt ataatatcat ctgtagttcc gaatgttatg
     3001 cattctcttg aaaacttttg tataaagtac tgtaaaaaac agccattaat agtaggtcca
     3061 ggcataaaaa caggtctaaa tataaaatat gataatccaa aacaagttgg ggcagataga
     3121 atagttaatg ctgtagcagg gatagaaaag tatggagcac caagtatact tgttgatttt
     3181 ggaacagcaa ctacattttg tgctatctct gaaaaaggtg aatatttggg tggaacaata
     3241 gcaccaggaa taaaaatatc tagtgaggcg ttatttcaaa gtgcgtctaa attacctaga
     3301 gtagaattag ctaagccagg tatgactatt tgtaagagta ctgtatcagc catgcaatct
     3361 ggaataattt atggatatgt tggtttagtt gacaaaataa taagtatgat gaagaaagaa
     3421 ttgaattgtg atgatgttaa ggttatagct acaggtggat tagctaaact gattgcttca
     3481 gagacgaaaa gtatagatta tgtagatggt tttttaacac tagaaggatt gagaataata
     3541 tatgaaaaaa accaagaata attaatatac agggaattgg gttatatatc caattccctt
     3601 tttatgatag atttctagct atatgtggta tattataatg aggaaataag aatttaaagt
     3661 taaatcacaa aataaaggca aaaataggag aaaaacaatg aaaataggaa atttagaatt
     3721 gaaaaataaa gtttttctat cacctatggc aggtgtaaca gaccttccat ttagattaat
     3781 ttgtaaagaa caaggatgtg ggcttttata tacagaaatg ataaatggta aggcactttg
     3841 ctatgatgat gaaaatacta aaaaaatgct taagatagaa gaggaagaac atcctgtagc
     3901 agttcagata ttcggttcag aaccagagtt tatgggaaga gcaacagaga taatgaatga
     3961 ttattcaaat gagattctcg atataaatat ggggtgtcca gctccaaaag tagttaaaaa
     4021 tggagatggt tcagcactta tgaaaaatcc taagcttgca gaagaggtat tgagggcagt
     4081 agtgaagaac tcaaaaaagc cagtgacttt aaagattcga aaaggctggg atgataatag
     4141 tgtaaatgct gttgaaatag caaagatagc agaggattgt ggaataagtg ctttagcaat
     4201 acatggaaga actagagaac agttttatac aggcaaagca gactgggata taattgcaga
     4261 gattaagaaa aatttgagta tacctgttat aggaaatggt gatgtattta caatagaaga
     4321 ttcaataaat atgttagaca aaactggttg tgatgctata atgataggta ggggtgctca
     4381 aggtaaccct tggatattta aaagaataaa ccattatatg aatacaggcg agattttgcc
     4441 agagccaact cttaacgaaa aaataagtac tgccattaag catttaaaac ttgcagtaga
     4501 agaacatgga gagtatgtag ctgtaaggga aatgagaaaa cacatcgctt ggtatttaaa
     4561 aggacttaga aactctgcaa aattaaggga tgaaattaac aaaatagaag actatcaaga
     4621 agttgtgtcg aaattggagt actatatgga agactccttg acataaaaat aatagtgact
     4681 tataatatag cgcataaatt aaaaaaagat tataaaattt ttaaaatata attaggaaaa
     4741 ttcctaagaa atttgtgaag gagttgtatt tataatggaa gaaaataaag agtttttatt
     4801 gacacaagag ggatatgata aattagaaga agaattagaa aacttaaagg ttgtaaagag
     4861 aaaagaagtt gcagagagaa taaaagttgc tatatctttt ggtgatttat ctgaaaatgc
     4921 tgagtatgat gaagctaaaa aggaacaagc acaagttgaa gaaagaattt taaaattaga
     4981 aaatatggtt agaaaagctg ttatcataga tgaaagcaaa atagacctta atgttgttac
     5041 aataggatca atagttaaag ttaaggattt agaatttgat gaagaggttg aatatactat
     5101 agttggttcg acagaagcag acccatatga tggtaaaata tcaaacgaat ctcctgtagg
     5161 gaaagcactt ttaggtagag ctgcgaaaga agttgtggaa gtgcaagttc ctgatggagt
     5221 tgctaagttt gaaatattag aaataagaag ataatttgga ggaaaaaaat gaaaaataat
     5281 caacaaagca atgaagaagc gcaaattcaa gaagacctta gtgaagtact tcaagtaaga
     5341 agagataaac taaaaaaatt acaagagtca ggtagagatc cttttaaaga aagtagatat
     5401 gatagaactc attattctat ggatataaaa gataactttg attctcttga gggtaaaact
     5461 acaaaaatag caggacgtat aatgagcaag agaatacaag ggaaagctgg ctttatagat
     5521 attcaagacc aagagggaag aatccaatct tatgtaagac tagatgctat aggagaggaa
     5581 gaatatagtg tattttcaac atatgatatt ggagatatag ttggaattga aggagaaatc
     5641 tttaaaacta aaaaaggtga aatatctgta aaggctaaat ctgtagtatt actatgtaaa
     5701 tctttacaag ttttaccaga aaaatatcat ggattaaaag accaagaact aagatataga
     5761 caaagatatg ttgacttaat agtaaatcca gaagtaaaaa atgctttttt aattagaaca
     5821 aaagcattaa aagcattaag agcatactta gatgatagag gatttttaga agttgagact
     5881 ccaatattaa atactatagc aggtggggca aatgctagac catttataac taatcataat
     5941 actttacata taccaatgta tttaagaata gcgaatgaat tgtatttaaa aagacttatt
     6001 gttggtggat ttgataaagt ttatgaaatg ggaagaatgt ttagaaatga aggtatggat
     6061 ttaaaacata atcctgaata tactgcaata gaattatatc aagcatatgc agactatact
     6121 gatatgatgg aaataacaga aaatgttatt gcacatatgg ctgaagttgc tacaggaagt
     6181 atgatagtta actatcaagg aacagaaata aactttacac caccttggaa aagaatgagt
     6241 atggaagatt gtgttaaaga atattctggt gtagattttt ctactataaa tacagatgaa
     6301 gaggcactag aagttgctag agaaaaaggt atagagataa aacctggaat gagaagagga
     6361 gaagtaataa atgctttctt tgaagaattt ggagaagata aattaatcca accaacattt
     6421 ataactcacc atccagttga agtatctcca ttatctaaga gaaatgttga agacccaaga
     6481 agaactgata gatttgaggc atttgctaat aagtgggagt tagctaatgc attttctgaa
     6541 cttaatgacc ctattgacca aaaaggaaga tttatagacc aattgagaaa aagagaatta
     6601 ggtgatgatg aagcttttga aatggatgaa gatttcttaa aagcattaga ggtaggtcta
     6661 cctcctacag gaggactagg aataggtata gatagagtaa ttatgttatt aactaactct
     6721 ccatctataa gagatgtatt attattcccg actatgaaac ctattgataa caatccaaat
     6781 aaagaagaag aaaactaaga aatattagca ttctactaag ttttaaataa agtttagcta
     6841 ttaaattatc aataaatagc taaattttat ttaaaatgtc agtgtggaat gctttttata
     6901 tgcttcaaag attcttttag atatttaatt tataaattac caacaaacgt tagaaattga
     6961 tattagtttt tgttgattga gactttatat ttagaaaata tgattgaaag taatttatta
     7021 tgaaaatatt tagaataatt tatgagaagg taaaaagaat aatttatgag aatactatat
     7081 ataaaaaatt attgggggaa tgtctgatgt ttcaagtaat taatttttta tgtttatttt
     7141 gtgttggatt tttggttctt gatgttatga tatatttttg taaggatgca atggatattt
     7201 ttgagggtac aactaatgtt aataaagtta agagtataaa tgtttgggca gatagagtga
     7261 gagctaattc atattcttat gaaaataaaa ttgcaaaata ggtaaaatta tatatgcatg
     7321 tattgtttgt aatatcaagg gttatatcta ttagttttaa ttatatttat taaaaaaacc
     7381 aaaagttata acctttttta aaataaaaaa caaaaaaagt attgacgaaa
//
LOCUS       DAEHWO010000129         7255 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEHWO010000129 DAEHWO010000000
VERSION     DAEHWO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7255
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.132"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(192..1031)
                     /locus_tag="KNP54_003741"
     CDS             complement(192..1031)
                     /locus_tag="KNP54_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBF0894595.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1055..1813)
                     /locus_tag="KNP54_003742"
     CDS             complement(1055..1813)
                     /locus_tag="KNP54_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBF0894596.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1860..2333)
                     /locus_tag="KNP54_003743"
     CDS             complement(1860..2333)
                     /locus_tag="KNP54_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBF0894597.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2362..2778)
                     /locus_tag="KNP54_003744"
     CDS             complement(2362..2778)
                     /locus_tag="KNP54_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBF0894598.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIVINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2825..3877)
                     /locus_tag="KNP54_003745"
     CDS             complement(2825..3877)
                     /locus_tag="KNP54_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBF0894599.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4273..4953
                     /locus_tag="KNP54_003746"
     CDS             4273..4953
                     /locus_tag="KNP54_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBF0894600.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5086..5406)
                     /gene="sugE"
                     /locus_tag="KNP54_003747"
     CDS             complement(5086..5406)
                     /gene="sugE"
                     /locus_tag="KNP54_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBF0894601.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5788..6615
                     /locus_tag="KNP54_003748"
     CDS             5788..6615
                     /locus_tag="KNP54_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBF0894602.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
BASE COUNT         2456 a         1316 c          843 g         2640 t
ORIGIN      
        1 cctcattctg attaaaaatc tttctgagat actttttaaa atattaaata ctacatatag
       61 cttacataag tttaaaattt aatctattat aaaattaccc taattgccaa actttttaat
      121 ataaattttc caacatccta caaatataat caatagatat agaatcctaa cttacaccaa
      181 tatatattta tttaaaatag tcctaaaata cctgtaatag ctcccactac tatcagtata
      241 aacattattt ttattggaga aagacctttt tttaatgcaa agagtactaa taaagtaagt
      301 accaaaggaa ttaatcctgg aaatatctta tcaagtaaat ccgtttgaag actaaattta
      361 aaatcaccac tagtataact tattggtgta gataaattga taaacctacc tacaagcccc
      421 cccatgacta aggtacctag tatagaagcc ccttctataa ccttatttac tattccacct
      481 tgaagtatac tttcaacagc ttttttccca tacttatatc catttgtcca cattccaaaa
      541 gaaattgaag tcattattat atattgagct attacaaata atataggtcc tgcaattgat
      601 gctcctccct cagttaaacc aatacaaaca gctaacacta taggagttat aactccttga
      661 gttaaagtat ctccaattcc cgctagtgga cccatcaagc ctgttttgat agcattcata
      721 ccatctccac ttatttcatc tgctccatta gctttttctt cttccatagc tattgttatt
      781 ccatgtataa cacatccaca tataggttct gtgttaaaaa atgctagatg agtctccact
      841 tcttgtttta actcttcctt atctggatat aattttttaa gtactggcaa cattgaatgt
      901 gaaaaagctg ttgattgcaa tctttcataa ttgtaattag attgtgcaaa gaaaaaccat
      961 cttaaccatg attttattac atctttcttg cttaacgttt tcttagatac ttcatttttt
     1021 atatctgaca taatattttc cccctcacat gtatttaaga tgtagcacta tcttttccgt
     1081 acttaattga agtaattgta agagcaagta ttactccaat aacagatatt actattatat
     1141 ctactttaaa ataaacagcc attagtattc ctaatatgaa aaagggcata gtaaacttat
     1201 ttccaatcaa ttttaaattc atagcaatcc caagtgctgg caacatagcc ccaattacat
     1261 taaatacatg taacacatta tcattcatta cttccaacat accatctatc gcatttggac
     1321 caaaataaac aactaataat gctggtataa aactcattgc aaataacagt atctgtggtg
     1381 gtactatatt tataaatgct actctatcaa cattcccttt ttgaacctct ctatcagccc
     1441 aatgtgcaaa aaaagaattt actgtcatct ttccaatcca aagtacagtt gcaacagttc
     1501 ccaatggtac agctattgcc attgcagtac ttacatctag cttagatgct atagctaaag
     1561 cagtacctac atatcctgca aaagctgggt cccccatctg agctccccct gctgatataa
     1621 aacctagata tatcatattt atacctgctc ctataattgc tccttgaaca gggtctccta
     1681 atataattcc cgttacaaat ccagccaata gaggtctatt ccatgtaaaa aatccaacat
     1741 aagtcaacca cggactccaa gaaagataat aaaaaattgc tattaatact gcttgaatta
     1801 gtgaaatgtg catattcttc ctccctattt tcttttaaag atttacaaga tagtcttctt
     1861 tacaataatg ttcctacatc aattttcttt gcatctggta ctatttgtat aaagcattta
     1921 acatcttttg atattagctc tctaaatatt tctttttctt catctgacac agatatattt
     1981 ttataaaaac tttttctacc aagccctgct cccatacctc caacattcaa ttcctttaaa
     2041 tctaccccac tatttactaa acctaagaca gttttagggt atttgaccaa tactattaaa
     2101 ttttcatctc cattatgtga ttttaagact tcagcacctg attctacatc atgtacttca
     2161 accttaacag ttgatggagc tgccatttgt aaaacttgaa ctataaatgg gtcctttact
     2221 actaaatcat ccacgattac tatccttttt gctgatgtaa tcttacacca agcagtaata
     2281 acttgcccat gtattaatct atcatcaatt cttgttaatg ctatattact cataattatt
     2341 cctccagatt tttaatttat tttacaactt taaaacagtt ttaacatctt tgattcctga
     2401 tatcccaact tcctcacata aattcttcaa gtcttttaac ttcatagtat ctctgtttaa
     2461 aaataactct aaaagcatag gtaaatttac acctgtcaaa cattctaact cacatacctt
     2521 agcaaattta tttattacaa tagcagatgt attaaatgga gttccgccat aaaaatcaag
     2581 caatactaaa accccttcat ccttatattt ctcaattcca tcttctaact ttctactaaa
     2641 ctcatctatg ctgtcaccat ggtttaatcc taaagtttct acattttcct gtttgcctac
     2701 tattaattca gcactttcta acattgcttt agccatattt ccatgtgtgg ctataattat
     2761 tcctgccata tgaatcatac ctttcttaac cttttttata tggattatta tttagtactc
     2821 taatctaatt atctatatta atcattatct taccaaagaa aatatccctt ttgtatactt
     2881 tttcaaaata agctggtact tcttctaaat ttattctatg tgttactaat ttttcaacat
     2941 tcatatcacc cttttgcata tgatacaatc cagcactcca ttcttttcct gggaatggaa
     3001 aggagtttcc aaaccaagtt ccctttacag ttaattcact tcttactatc ttttcaaatt
     3061 gctctctagt caaagctaca tccccatatg gtacacctgc atacaatact gtacctccct
     3121 ttttagctag caacagtact tgaccacatg tcagtggagt accagccgat tcaataacaa
     3181 tatctgcacc atctccatca gttaaccttt ttatttcttc tacaatattc ttttcttttg
     3241 catttataca aatatctgcc cctaactctt ttgccaagtc taacttctca tcaaatacat
     3301 ccacagctat tatttttgta gaaccaaata tttttgccca ttgtattgaa aataatccta
     3361 ttggacctgt accaagtact acaacagtat ctccaacttt agcttctgac ctaaaaagac
     3421 catgtcctgc tatacatact ggttctagcg cagcggcagt ctcataactt atctcatctg
     3481 gtatttttat taaatttctc tctttcacct ttgtatactc tgcaaaacaa cctccaagtt
     3541 ctttatttcc tattattgct acattattac atcttgaata caagcctttt ttacattcat
     3601 cacattcaaa acatggcata gctggacaaa cagcaactct atctcctatt ttaaaactcc
     3661 ttacttcttt accaacctgt gccacttctc cagaaaattc atgccctaaa atttctccaa
     3721 ccatatgtgg acctgtcttt gaatattttg atatatcaga accacatatt ccagctactt
     3781 ttactttaat tattacatca tctttttcta atatttttgg tacatccaca tcctccactc
     3841 ttgtgtctct tataccatag aatctaactg acttcactat taaccacccc tactttttat
     3901 ttgagaatat atccctattg tttatatgtt aaatatctaa agcaactttc atgccaatat
     3961 atgtaagcat tgtattcatg cattttataa aattatcatt aaatgtgtgt caaagtgtgt
     4021 caaaagtttc ttatattaaa acttatgtgt gtcaatataa acgacactaa cattttatat
     4081 tagttctctt attataagtt ttataaaatg tacttttttt gttattttta taaaattgtt
     4141 cggaaatttc ccttctattt gtgatataat attaaatata aggtatcaat ataaattttc
     4201 atgcgaatat cagaactttt ttgacactaa tgccttattc aatataataa tttaactttt
     4261 tggaggttgt ttatgaaaaa agtgtatcaa ggaaagacta aagatgtttt tgaattagat
     4321 aatggaaatt acttacttaa atttaaagac gatgtaactg gtaaagatgg agtatttgac
     4381 ccaggcgaaa atagtgtagg tctaagtata gatggaattg gtagagctaa tttagagaca
     4441 tctgttaagt tctttgaaat tctaaacaat gctggaatta aaactcatta tgtaagtgct
     4501 aatttagaag aagcaactat ggaagttcta ccagcaaaag tttttggtaa tggattagaa
     4561 gttatttgtc gttatagagc tgtaggtagt ttcttacgtc gttatggttc atgtgttgaa
     4621 gaaggtgcta aactagattg ttacgtagaa gcaactttaa aagatgatga ccgttgtgac
     4681 cctcttataa catctgaagg tttagaagct ttaaacatta tgactcaagc tcaatttgat
     4741 tcaatgaaaa gcatgactca aaaaatttct aacatagttc gtgatactat agctgaaaaa
     4801 ggtcttgagc tttatgatat taaatttgaa tttggattct acaatgatga agtaatctta
     4861 atagatgaaa tagcatctgg aaatatgcgt gtttataaag atggtgtaat agttgaccct
     4921 atggatttaa ctgctctttt attagataaa tagtatatac atataattta caaatataat
     4981 aaacttataa ataagataag ctatgaagta aagacttttt aaatgttgat tatttttaaa
     5041 cattttctcg cctttaattt catagcttat ttaaattaat atactctaat tagtagataa
     5101 tagctttaac cctacaattc ccaccacaat aaaacctata catgcaattc ttgatatact
     5161 aataggctca tttaaaatag ccatgcctac aatagctgta ccgacggtac caattccagt
     5221 ccatattgca tatgaagttc caagtggaag atgttttagt gctaatgaca aaaaataaaa
     5281 acttacaatc attccaacaa cagtaagtat acttggagtt aatttagaaa atccatgtga
     5341 attttttagt tgaaaagccc aaaacacttc aaacaaacct gcaacaaaca aaaataacca
     5401 tttcataaat tcatccctct tttcaaatat gtctcttatt tttccaataa aataacctga
     5461 gaaatattat aaaatatctc ccaggttttt gtccttccgt gttcacaaca aaaactatgt
     5521 tgtgggtttt atctcggacc agaccaatca ttaataattg cggaacccta taaaactcta
     5581 ttaattattc tattttatct ataataatac tatcaacata tataaaaaaa gtcaatatat
     5641 gggttccata tataataaaa ataactttta tatacctttt aatattctta ttcacttctc
     5701 tccataccca tttgggtcaa tctaagaata tctaattttt atttaatatg ttataataac
     5761 ataaaaatat tgaaaggagt aatttctatg aatttctata aaattgcagt atgtcagatg
     5821 attactacag aaaataaaat tgaaaatatc aatcatgctg tagatatggt aacagaagct
     5881 gccatcaatg gagctaaaat tgtagttttg ccagaaatgt ttaactgccc atatgaaaat
     5941 aaatattttc ctaaatttgc tgaagaatat ccaggtgaaa caacaacgat attaagtaaa
     6001 ttagctgaga aacatggaat ttatctagtt tctggtagta ttcctgagtt agaagatgga
     6061 aaaatctata atacttgcta tgtatttgat aaaaatggag ctctaattgg aaaacatcgt
     6121 aaaatgcact tatttgacat tgaagttaca ggaaaagtta gttttaaaga atcagatact
     6181 cttacagctg gaaatgatgt cactgtaata gataccgaat atggaaaagt tggtatagct
     6241 atttgctatg atattcgttt ccctgagtta tcacgtttaa tggctcttaa aggtgctgaa
     6301 atcgttatct tacctgctgc atttaatatg actactggtc ccgcccattg ggagttatct
     6361 ataagaatgc gtgctttaga taatcagata ttctatgttg gtgctgcacc tgctagaaat
     6421 atgaatgctt cttatatagc ttttggaaat tcaagaattt cagacccttg gggaagaata
     6481 attgctcaag ctgatgaaaa agaatgtatt atttatgctg acattgatag agatttaatt
     6541 cctgacataa gacaacagtt accacttctt aagcacagaa gaactgattt atatgaactt
     6601 aatactttga aataaaacag aacataaccc cataaatcat aaattaagtg ttaaaaaaat
     6661 ttatggggtt ctcattaatt tgatttaaaa ttaatttcat aaaaataatg ctaatattaa
     6721 tttaattaaa taatactaat aattactaat gattatgcta attatcagca tttactaatt
     6781 taatcactat tagttatttc ttttattaaa tatctttact tttttactta ttatgtcttc
     6841 tagctttaca tttggattat ggtatttctt tctattttta gtcacatctt tctattgaat
     6901 tacttgctta aaacaccaat gcacacatgc cagataatgt tcacaattat ttagaaatct
     6961 tgctctacct tcttcaatgt tgatattatc tctcctagtt gatattatct ttcctaaaat
     7021 ttcttttaat taaaaaacaa cattagttga tatatcaagt atattttaag caactgaaaa
     7081 aaacaataat aattgatata tcaactaatt aatgtagatt aattcatttt tataatttat
     7141 atacttttta attaatctac cttatttaat taaaatcctt cctttctatt tatccatttt
     7201 caacttaaat tataagattt catcagctat atttttgcat accaataatt attaa
//
LOCUS       DAEHWO010000130         6974 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEHWO010000130 DAEHWO010000000
VERSION     DAEHWO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.133"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            15..548
                     /locus_tag="KNP54_003749"
     CDS             15..548
                     /locus_tag="KNP54_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBF0894603.1"
                     /translation="MTEVIIVNDARIISQIKAGKKELFDTLIKKYYDSIYCYCYRHVD
                     NKMTAQDLTQDVFVTVINNIENYKHYGKFENYLYVIAKNKCKDFWKKKQPIYLESLDK
                     EISNQELSDIENKMFIKEALTKLPELEFEVIILRYYHDLRFKDIAKIMESSVSVTKYR
                     MSRALKKLELYLEGGKL"
     gene            545..1306
                     /locus_tag="KNP54_003750"
     CDS             545..1306
                     /locus_tag="KNP54_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894604.1"
                     /translation="MNNKEIKRSLQKYKVPKYDSSALEKTIKTIHELTLSNTYKRMNN
                     KDFFISQIGFIRKRTWIMQFLILCTICIFLFSTSADSNSFYNSLSLISIASPLFVLTN
                     IEELTKVYNSSILEIEFSTKNTLHKIIATRMLIFGISDLLFMIIILVSAKQIIDVNIL
                     YIIIYILVPFNLMCIGCMEIINRNKGKHTNYYCMIYGISLVLLIVTLSNFRDNLYQFE
                     AINQWLIVFLVTAVTLIYEIRKTWRHLCSFENIII"
     gene            1344..2210
                     /locus_tag="KNP54_003751"
     CDS             1344..2210
                     /locus_tag="KNP54_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894605.1"
                     /translation="MELSVERLTKQYNNKIIVDKIDFKLNEGIYGFLGENGAGKTTLM
                     RMICGILSPTSGEVKVDGKNNLDMGEDFRDMIGYLPQNFGYYPDFTAKEFMLYIASLK
                     GLMPSYAKRKTQELLEMVGLSEVINKKIRTFSGGMKQRLGFAQTLLNDPKILILDEPT
                     AGLDPKERVRFRNLISEFSKEKIVILSTHIVSDVEYIADKILIMKKGRFVLTGSIEEV
                     TSKIKDKVWKCVVNENEIDYMSDRYCLANIHHSGGVANLRIVSDIKPHDNACNLKPTL
                     EDLYLYCFNEVL"
     gene            2231..3472
                     /locus_tag="KNP54_003752"
     CDS             2231..3472
                     /locus_tag="KNP54_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894606.1"
                     /translation="MSTLIKFELKKIIKRKSTIAVILGSLFLSIILFALMPIQEKAND
                     ESGKEYRGLQAIELKKQQSKLNEGYITDKKVKNSIRDYQKMFNNPNNITTDEGGFSNF
                     KPDIYWKFFYPNKAFYNFIIESYSNPNDYNPEIIKSMPLEDGVNFYKFRNEKVNTILN
                     MEYPDKNYTQKEKDFWLSKNKDIEEPYLNGYYQGWNYFLLARDLLIFTIVAVCISTAS
                     VFSGEYQSGADSIILSSKYGKTKVITAKIVSSFLFGTIIFTINTIVSIGILLLSFGID
                     GWNLPLQLTTSSIPYPYTFLQAILLSVLIIYMILILLISFTLLLSSYMKSPFPVLITN
                     IILLFVPIFLKYSETNKLYNQILNVLPSNAISFSFTNYVDYKFGNLIIALPTMIIFTC
                     LVLTVVFLPFIKNNFKKHQVN"
     gene            complement(3696..4268)
                     /locus_tag="KNP54_003753"
     CDS             complement(3696..4268)
                     /locus_tag="KNP54_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBF0894607.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKGESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQKSV"
     gene            4654..5388
                     /locus_tag="KNP54_003754"
     CDS             4654..5388
                     /locus_tag="KNP54_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBF0894608.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGTNLHWPVDGYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(5531..6022)
                     /locus_tag="KNP54_003755"
     CDS             complement(5531..6022)
                     /locus_tag="KNP54_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBF0894609.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            6371..6754
                     /locus_tag="KNP54_003756"
     CDS             6371..6754
                     /locus_tag="KNP54_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894610.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYNG"
BASE COUNT         2710 a          791 c         1006 g         2467 t
ORIGIN      
        1 aatcgttata tataatgacg gaggtgataa tagtgaatga tgctcggatt atatcacaaa
       61 taaaagcagg aaaaaaagaa ttgtttgata ctctaataaa aaaatactat gatagcatct
      121 actgttattg ttatcgccat gtagacaata aaatgactgc acaagattta actcaagatg
      181 tatttgtaac agttataaat aatatagaaa attataaaca ttatggtaag tttgaaaact
      241 atttgtatgt tattgcaaaa aacaagtgta aggatttttg gaagaaaaaa caaccaatat
      301 atttagagtc attagataag gagatatcaa atcaagaatt atctgatata gaaaataaaa
      361 tgtttataaa agaagctttg actaaattac cagaattaga atttgaagtg ataattttac
      421 ggtattacca tgatttaaga tttaaggata ttgctaaaat tatggagtca agcgtctctg
      481 tcacaaagta caggatgagt agggcattaa aaaaactaga attatatctg gaaggaggta
      541 aattatgaat aataaagaaa taaaaagaag tctacagaag tataaggttc ccaaatatga
      601 ttcttcagct cttgaaaaga ctattaaaac tatacatgag ttaacgctta gtaatactta
      661 taaaagaatg aataataaag acttttttat atctcaaatt ggttttataa gaaaaagaac
      721 ttggattatg caatttctaa tactatgtac aatatgtata tttttattta gtacatcagc
      781 agatagtaat tcattttata atagtttatc cttgatttct atagcatcac cactttttgt
      841 actgacaaat atagaagaat taacaaaagt gtataatagt agtattttag agatagaatt
      901 ttcaacaaaa aatacattac ataaaattat tgctactaga atgcttatat ttggaataag
      961 tgatttattg tttatgatta ttattttggt atctgcaaaa caaatcattg atgtaaacat
     1021 tctgtatata ataatttata tactagttcc ttttaaccta atgtgtatag gatgtatgga
     1081 aattataaat agaaataaag gtaagcatac aaattattat tgtatgatat acggtatatc
     1141 tcttgtatta ttaatagtta cactgagtaa ctttagagat aatctatatc aatttgaagc
     1201 aataaatcaa tggctaattg tttttctagt cacagcagta acattaatat atgaaataag
     1261 aaaaacgtgg agacatcttt gttcatttga aaatattatt atctaagtaa aaaataagaa
     1321 tacacagtat caggaggaat agtatggagt taagtgtaga acgtttaaca aaacagtata
     1381 acaataaaat tatagtagat aaaattgact ttaaattaaa tgagggtata tatggatttt
     1441 taggagaaaa tggagctgga aaaacaactc ttatgagaat gatttgcgga atattaagtc
     1501 ctacatctgg agaagtaaag gtggatggta aaaataattt ggatatggga gaagatttta
     1561 gagatatgat tggatacctt cctcaaaact ttggatacta cccagatttt actgccaaag
     1621 aatttatgct atatatagca tcattaaaag gattaatgcc tagctatgca aagagaaaaa
     1681 cacaagaatt attagaaatg gtaggattat cagaggtaat taataaaaaa ataagaacat
     1741 tttctggagg tatgaagcaa aggctaggat ttgctcaaac actacttaat gaccccaaaa
     1801 ttttaatatt agatgagcca acagcagggc tagaccctaa agaacgagtt agatttcgca
     1861 acctaatttc agaattttct aaggaaaaga ttgttatatt gtctactcat attgtgtctg
     1921 atgtagaata tattgcagat aaaattttaa taatgaaaaa aggaagattt gttttaactg
     1981 gctcaataga agaagtaact tcaaagataa aagataaggt atggaaatgt gtggtcaatg
     2041 agaatgaaat agattatatg tctgatagat attgtttagc aaatatccat cattctggtg
     2101 gagttgcaaa tcttagaatt gtaagtgata taaagccaca tgacaatgca tgcaatttaa
     2161 aaccaacatt agaagattta tatttatatt gtttcaacga agtactataa atatacataa
     2221 ggagataggt atgtctacat taattaaatt tgagttaaaa aaaataataa aaagaaagtc
     2281 tacaatagca gttattttag gaagtttatt cttaagcatc attctttttg cattaatgcc
     2341 aattcaggaa aaagctaatg atgaaagtgg aaaagagtat aggggtttac aggctattga
     2401 gctaaaaaag caacaatcta aattaaatga gggatacata acagataaaa aagtaaaaaa
     2461 ctcaatcaga gattaccaaa aaatgtttaa taatccaaat aatattacaa cagatgaagg
     2521 tgggttttca aattttaaac cagatattta ttggaaattc ttctatccaa ataaagcttt
     2581 ttataatttt ataatagagt catatagtaa tccaaatgat tataatccag aaataattaa
     2641 atcaatgcct ttagaagatg gagttaattt ttataaattt agaaatgaaa aagtaaatac
     2701 aatattaaat atggaatatc ctgataaaaa ttacacacag aaagagaaag atttttggtt
     2761 gtctaaaaat aaggatatag aagagcctta tttaaatgga tattatcaag gatggaatta
     2821 ttttctattg gctagagatt tactaatttt tactatagta gctgtctgca taagtacagc
     2881 ttctgtattt tcaggagaat accaatccgg tgctgattca ataatattat cttctaaata
     2941 tggaaaaaca aaagttataa cagctaaaat agtaagttcc tttttatttg gtacgattat
     3001 ttttacaata aatacaattg tgtctattgg tatacttctt ttatcttttg gaattgatgg
     3061 atggaattta ccattacaac ttacaaccag ttcaattcca tacccatata catttttaca
     3121 ggcaatatta ctaagtgtgt taattattta tatgatatta atactattaa ttagttttac
     3181 acttttatta tcatcttata tgaaatcacc ttttccagtt ttaattacaa atataatatt
     3241 actatttgta ccaatatttt taaaatatag tgaaacaaat aagttgtata atcaaattct
     3301 caatgtttta ccatcaaatg ctatttcatt ttcatttact aattatgtag attataaatt
     3361 tggtaattta ataatagctt tacctacaat gattattttt acatgcttag ttcttacagt
     3421 tgttttttta ccttttatta aaaataattt taaaaaacat caagttaact aaaatatata
     3481 ttataaaaag aaggtgtctt aaaatgaact ttttagctta ttaggcactc ttctttgtat
     3541 taatttaaat atattttagt attagattaa atatgttttc atcattttaa caatgaaaaa
     3601 gagctttatc tctattttga gatagctctt ataaagttaa atattaaatt gataactata
     3661 aaatatgtag tttgaattta taatttgtgt tataatcata ctgatttttg tacatcagtt
     3721 cttacattaa cattgcctgc ttttagattt tctccaatag taagaccttt ttcttttaga
     3781 acatattcaa aagtcattag tggaactcca ccttttctac cacctaatat ttcggttcct
     3841 tttaaatcat tgtaagagaa attaggcatt tttttcctag caactagaaa actaccatct
     3901 ctttttgtca attgagcaaa gttcactgca taatcgtttt tgttttgatt atatacatat
     3961 atagatgctt caggacccat taaacctacg tttgcttcac ctgaaatcaa agctgccata
     4021 gttttatctg caccttgggt atttataagg tcaatcttta taccttcatc ttcaaagaat
     4081 cctttcgtaa tagcagcata ctgtggagca taaaaaacag agtgagtaac ttctgctata
     4141 gttactttat ccagattttt agacgaagaa gattcacctt ttttgtcatt agagttaaaa
     4201 tcacatccag ttagacatat tgtacttaca atgatagagc ttgctattgc gactattttt
     4261 ttaaacataa taaatacctc ccataagaca tacgaatagt atatagtatt aaaaatttat
     4321 tgtagttgtt acaaaaatgt atctatgctt ataatatttc tacaaaaact taataataat
     4381 tttcagcttt atgtttagtt ttttcagtaa tgtgtaatat tggataaatt atattgatta
     4441 tttataaact aagtaataaa attaaaataa tatcactttt ttgtctatta tatataagga
     4501 aaaatttttt aataatataa atcatattca tttatattat taaaaaattt gtttatagaa
     4561 acttttatta ttttatataa aagtgataaa aacttatatt ttgtatttaa tagagtgttg
     4621 ctaagtgaat atatttaaaa tggaggaaac tttatgaaac aaaataaata tgatgatgat
     4681 agatttttta ataaatacag taaaatggaa cgttctacaa atggattagc aggtgctgga
     4741 gagtggcatg ttttaaaaaa aatgttacct gatttcaaag gaaaaagagt tttagattta
     4801 ggatgtggat ttggatggca ttgtcaatat gcagttgaga atggagcaat ttctgctgtt
     4861 ggagttgata tttcagaaaa aatgttaaaa gaagctagaa acaaaacgca acttgataat
     4921 ataaattaca tatgtatgcc tattgaagat attaattttc caaaagatag ttttgatgta
     4981 gttattagtt ccttggcatt tcattatatt caatcatttg aagatatatg taagaatata
     5041 agtaattgtc tttcaaataa aggtaatttt gtattttctg ttgaacatcc tatatttact
     5101 gcatatggaa gtcaagagtg gtactgtgat aaagatggca ctaatctaca ctggccagta
     5161 gatggatatt ttgaagaagg agtacgtaag tcaaattttc taggagaaga ggttataaaa
     5221 tatcataaaa cattaacaac ttatttaaat acgttaatga aaacaggatt tgaaatatta
     5281 gaaattattg aacctcaacc agaagaaaaa ctgttagata caattcctga tatgaaagat
     5341 gagctacgta gacctatgat gttacttgta tctgcaaaaa aaagataagt aaatataaat
     5401 aatcattatt gtagaaaaaa agttgtagaa aataattaca ctaatggaga tgattatacc
     5461 agtggtatta attacaccag tagtaaggag gcaaaagcat tcgttgcttt tgccattttt
     5521 taagttgcaa ttatacttct acgtagtata tttcgtttcc attttcttct ataagctttt
     5581 tcatatcttc aaattttaaa aatacagtag cagtattatc atttggatgt atacctattt
     5641 tatccatttt taataaatct ttatcaaata caacttttac aacagcctct ttatcattta
     5701 atataccaaa aggagtcaca gctcctttag taagtttcaa gtatttttga agtctttctt
     5761 ccgatgcaaa actaagaggt ttactatcaa tttgttgacg aatatctttt aaatctgctt
     5821 ttttgtcttt acctaataca actaaaaaat gttcttttcc tttagcatca cgaagaaata
     5881 ggttttttac aacaaattcc atatgtaatg tttttaattc ttccatttct tcaattgtat
     5941 aaactggtgg atgatttaca gcctcataag gtatgcttaa ctcatctaat tttttatata
     6001 cttcctgttg ttgattgttc atgatttcct cccattagaa atttatttta tatataaata
     6061 atattatcac agaaaacttt aaaagaaaac gttttatata atatagacaa tagattatat
     6121 ttttataaag aagcaagaat actcaataaa acttaaagaa attaaacaat ttctaaaaat
     6181 accttgaaaa tagaacctta tttgccattt ataaattata taaaaaggga ttatataaag
     6241 tcatatatga aaaaactata ttatactatc ttttcttttt ggaataaact atactttaaa
     6301 tatagatatt taatttaaat aaattttaca gtattaatag taaattatct tagaaaggaa
     6361 tgtgctttat atgtctacag acaaagttgt tggaatcata gatgaagaaa cggcagaact
     6421 tgcaggaatt gaatatactg gtaaaattta tgcttcttct ggtgttataa aacatataaa
     6481 gaaaaaacat agatgtcaac tgagtaagga tatttttaat gatataatag acactataaa
     6541 aatggtatta aagtcacctg aatatatagg aagtcatcct aaaaaacctg gaaaaagtgt
     6601 ggagtttata aaaaaaattg atgattatat tttagtagct acagaattag atacaaaaaa
     6661 aggatattta tatgtatctt caatgtatgc tataaaagaa gcaaaattag aaagtagagt
     6721 aaacagtgga agagtaaaac aatataatgg ttaacataat attattaatt ttccctaaaa
     6781 tattgaaaaa tattattata taagttataa tattaatata cacgtagata tttattagtt
     6841 agatttgagg ttggaaaagg cacccaatac gctactatag agtagttaat agagatgcag
     6901 gatacgccgc cctgccaaat ctaattaaat taaaaagaga ggattaattc ctctcttatt
     6961 gtttttttga gata
//
LOCUS       DAEHWO010000131         6905 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEHWO010000131 DAEHWO010000000
VERSION     DAEHWO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.134"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            252..1241
                     /locus_tag="KNP54_003757"
     CDS             252..1241
                     /locus_tag="KNP54_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBF0894611.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(1693..2409)
                     /gene="dapD"
                     /locus_tag="KNP54_003758"
     CDS             complement(1693..2409)
                     /gene="dapD"
                     /locus_tag="KNP54_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBF0894612.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(2633..3382)
                     /locus_tag="KNP54_003759"
     CDS             complement(2633..3382)
                     /locus_tag="KNP54_003759"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBF0894613.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(3449..4336)
                     /locus_tag="KNP54_003760"
     CDS             complement(3449..4336)
                     /locus_tag="KNP54_003760"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBF0894614.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(4453..5454)
                     /locus_tag="KNP54_003761"
     CDS             complement(4453..5454)
                     /locus_tag="KNP54_003761"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBF0894615.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(5879..6760)
                     /locus_tag="KNP54_003762"
     CDS             complement(5879..6760)
                     /locus_tag="KNP54_003762"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBF0894616.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
BASE COUNT         2355 a         1116 c          918 g         2516 t
ORIGIN      
        1 tgacttcata ccaaaaagag tgccccatga actaaaaagt taattttgaa ataccatatt
       61 catatatcat atgatttatt tggaaatcaa tattaataca ttaaaataac taaatacatg
      121 tatgcataaa gatgtataaa aaatatataa acatatagta ttaattttaa attcaacaat
      181 ttaattgtta aaagtgttat tattaaatta gaaatatctt aacttaatat actgagatgg
      241 gagtgataga tatgttaaaa gaagaaaaaa cttatcaaga gaaagacgca aaagtattca
      301 atggagtggc agctttgata atgattttat tatttttagt agtttcaata ggtatcatgg
      361 tttttgggat agtaaaactt gatagtggat ttactggaat aggttcactt atgttaattt
      421 tgggacttgt atttatagta gtagatttta tcctattttt tgggctaaaa atgattaatc
      481 ctaaagaagc tatagttcta gttttgtttg gtaactatta tggaactata aaaaaagaag
      541 ggtactattg ggtgaatcca ttttgttcag caataaaccc agcagtatca agaattaatg
      601 tatcgaaatc ttcatctgat gaaaaggtag atatatcaac taattcaagg ggcaaaaaag
      661 tatctttaaa aacaatgact cttaataatg aaaagcagaa agtcaatgat ttattgggaa
      721 atccaattat aataggagtg gttgtaattt ggaaggttat agatgcaaca aaggcagtat
      781 ttaatgtaga taattataat acattcttat ctattcagtg tgattctact attcgcaatg
      841 tttcaagact ttatccatat gatgtatctg aagatggaga tgaaaaatct cttcgtggta
      901 gtagtcagga aatagcagat agattaaaag atgaattaca atcaagggtt gatattgcag
      961 gaattgaagt gtgtgaagtg agaattactc atctttctta tgcaccagag attgcagcag
     1021 caatgttaca acgtcaacaa gcagaggcta taatagcagc acgtaaaaag attgttgagg
     1081 gggctgtaag tatggtagag atggcattga ctaatttaag tgaaaataat gttgtgactt
     1141 tggacgaaga acgtaaagca gctatggtaa gtaatctgtt agttgtgctt tgtggcaata
     1201 aagatgcaca accagtggta aacagcagtt ctatttatta aattataaaa agtttaatag
     1261 tttattttat tgatatatag aaaatttagt agttcatttt attaaattat agaaagatta
     1321 atggtttgct ttattgaatt ataaaaagtt taataattta ttctattgat atatagaaaa
     1381 tttagtagtt cattttatta aattatataa agattaatgg ttttcacttt attaaattat
     1441 aaaaagttta atagtttatt acattgatat attgaaaaat tgaaggaaat aaaaatactt
     1501 gtcagcaaga aataaaaatg atataagaat gaataagaga attgtaaaaa aataaaatga
     1561 ttataaataa aagataaaaa tattgtaaaa aagagggtgc ctctggtgaa ttaaattcac
     1621 acagagacac ctttttaatt aattttttaa attagtatat tattgtttaa ttaatagtat
     1681 agtactattt aattaatcta aatttctaag gtcttccata agcttagttt tgtcagccgt
     1741 tttttcatct ttcattttta taactttagc aggagaacca gcaacaacgg caccagcttc
     1801 tacatcagta gttacaacag caccagctgc aacaacagca cctttaccga ttctaacacc
     1861 ttcaagaata actgcattag ctcctattaa aacatcatct tcaactataa caggagtagc
     1921 agaaggtggc tctaaaacac cagcaacaac agcaccagca cctaagtgaa catttttacc
     1981 aagagttcct ctagctccaa taacagcatt catatctacc atagaacctt caccaataac
     2041 agctcctata tttataacag ctcccatcat tacaacagca tttttttcta tagtaaccat
     2101 gtctcttatt attgcacctg gctcaattct tgcatgttca cttaaagtat tttttagagg
     2161 aatagcagaa tttcttctat catattctac atgagtatct gttatatcat ttccatgttt
     2221 atctaatact tccattatat cctcatagtc acctacaaat atataagaac cattacttcc
     2281 gaatacctta aatttatcag ttgattggaa gtgtaaagag ttagtattta catatacctt
     2341 aacaggtgtt ttctttttaa cttcttttat ataccttgct atttcataag catcgtttaa
     2401 atttaccatt tgttaattct ccttgtattt cattatattt cttttattat atacttattt
     2461 gtcaatttta gtatatactt acttcttatt atttatattt tattttagtt agtttttatt
     2521 gtatagacat agtattaaat aaatttatta tatatgtttg atttgtattg cgtattatta
     2581 tatctatatt gcatatgttt aatttatatt gtgtattatt atatttatgc tattatccca
     2641 acatgctgtc catattataa aatcctggtt tttgcttaac taagtatttg gcagcagcta
     2701 tagaaccact tgcaaagata ccacgagatt gagcttgatg gcttattgta agaacctcat
     2761 tgtctccagc aaatagagca tcatgttcgc caacaatatt tccacctctt atagcatgaa
     2821 taccaacttc atttggttgt ctttttgcac tacgaccata tctaccataa ttattttcaa
     2881 cgtttggcaa aacctctttt atagcgttag caatcataac agctgtgcca cttggggcat
     2941 ctacttttct gttgtgatgt ttttctatta tttctatatc aaatccttct agtaatttag
     3001 ctgcatcttt aaccaatttt actaatacat ttacaccaag agacatatta tatgattgga
     3061 atacaggaat aactttagcc gcttcacgta ttttgttcat ttcgtcatca ttatatccag
     3121 tagtagcaat tactaaaggt gttttagtct ttaaaacgta agataagata ttatctaaat
     3181 tagagtgatg agaaaaatct ataactacat cagcttcctc aactatagta ctcatatctt
     3241 cataaatttt aaggtcgcct tcatagctat ccagacctct agctgcaaca caaaccaatt
     3301 ctaattcatt atcttctctt atagtatcgg ctaaaatctt acccattttt ccatcataac
     3361 cagttgctat aacttttaac ataatttcct cctatgatta agggctaact tttgaccaaa
     3421 cttacttttt accatgcatt aatctttact atgcattaac ttttagccca aagttaacta
     3481 attctttctt taatacttct aaatttgctg ggtccatttc tgctagaggt aatcttaaat
     3541 ctccaacatt gaatcccaat aaattcattg cagtcttaac tggtatagga tttacttcta
     3601 taaataaagc tgcgattaga gcatccatac caagttgtaa ttttctagaa ccttcaatat
     3661 cgccttcaaa gaatttagct accaaatcgt gagtttcttg agggcaaaca ttagcaagta
     3721 ctgatataac tccttgacct cctaaagata ataaaggaag tatagtatca tcattaccag
     3781 agtagatagc aaagtcatct ggaactaaac tagctatttc tgcaacctgt cctaggtctc
     3841 cactagcttc ttttacagca actatgttat caattttagc aagttcaact ataaggctag
     3901 gacttatatt tacacaagtt cttccaggga cattgtaaag tataattgga agtttaacac
     3961 tgttagctat tgtttcaaaa tgacgcttaa gtccagcttt attagcttta ttgtaataag
     4021 gtgttattat taatagagca tctactccta atttttcagc ttcttgactt aagttaactg
     4081 agtgcatagt atcattagaa ccacttccag ctataacagg aactctttta ttaacttttt
     4141 caacaacata cttaatagta gcaagttgtt cttcatcagt catagtatta gcttcaccag
     4201 tagtaccaca agatactata gcatcagtac cattagctat ttggtattca actaattcac
     4261 ctaatttgtc aaaatcaact ttgttatcct ttgtaaatgg tgtaactaga gcaacagcag
     4321 aacctttaaa tatcatataa aatcaatccc ctctttttta tttttgtgtt ttatattaca
     4381 gttacttcta atgcttgttt ttgagttact attaatattt tacaaaatta tatatttata
     4441 caagtttgta tattatacta aatcgtatga taaagccatt tcagctattt gaattgcgtt
     4501 agttgcagca ccttttctta tattatcagc aacaacccaa agatttacac cattatcaac
     4561 actaaaatct cttcttattc ttccaacaaa cacttcatct ctatcatcaa attctacagc
     4621 agttggatat tcgtttttag caggattatc aactactaca acacctggag cttcttcaag
     4681 tgtttttact aaatcatcta actcaaatgg attgttaaac tcaacattta tagattcact
     4741 atgaccattt tttactggaa ctcttacagt agttgcagtt atttttaaat cgtagttatc
     4801 aagtattttc atagtttcat ttaccatttt catttcttct ttagtgtatc cattttcagt
     4861 gaatgaatct atatgaggaa gacagttgta agagatttga tgagggtaga atccagtagg
     4921 attaccgttc attcctttct ctaaatcttc aacaccttta acaccagaac cagatacagc
     4981 ttggtaagta gagtaaacaa ctctcttaat tttgtattta tcatcaagag ctttaagggg
     5041 aaccatagct tgtatagtag agcagttagg attagctatt atacccttat gattttttat
     5101 ggcttctgga ttaacctcag gaactactaa aggcacatct ggattcattc tccattgact
     5161 agagttatct actactaaga ttccatttga agcagctatt ggagcatact tttcactaat
     5221 acttccacca gcagagaata atgctatttg tatgcctcta tcagtaaatg aagtttcctt
     5281 taattcttct actatatatt ctttaccaca aaacattact ttagaaccag ctgatttaga
     5341 agaagagaat aaaaatagat tttctattgg aaaatttctt tcttctaata cttttaaaaa
     5401 tgttctacct accattccag tagcaccaac tattgctaca tttacttttt tcatataaat
     5461 tcaccccaat tttaaattat taaaacatta ttttatttta gttatacaag taagatatgt
     5521 taatattttt atatatccaa aaactttaat attatattaa caactttaat tatatacaaa
     5581 aaacgtacaa aggtatactt tgtacgtcta atttatcact caaagtaaac cctgtagctc
     5641 atcacctaca aaaataagtg acagtattac acatgttatg tgcaatccca gaaaatatta
     5701 ttgcaagaaa tattttcttc ggctgtaaat cctttttcca atcattaaca cctgccagct
     5761 actattggat actcttagtt acagctacct ctaccctagg ttaataggat attaaaattt
     5821 gattattcta ataataatac atatttaaga aaaaatcaac ttatttatat aaatattgct
     5881 aaaatttaaa tccaaaattt gtcaattctt gttttaacac attaagatta gtttcttcca
     5941 tttcagctag aggaagtctt aaatcaccaa cattaaaacc taaaatgttc atggcagttt
     6001 taacaggaac tggatttact tctataaata aagcagcaat taaagcatcc atatcaagtt
     6061 gtaatttttt tgagccttca atatcacctt caaagaattt agttactaaa tcatgtgttt
     6121 ctttaggaca tatgttagca agtacagaga taacaccact tccacctaat gataatagtg
     6181 gtagtatagt atcatcatta ccggagtata tagcaaagtc tttaggtact aatttagcta
     6241 tttctgcaac ttgagctaag tctccacttg cttccttcac agcaactata ttatctattt
     6301 tagcaagttc agccacaaca gatggcttta tattcacttt agttcttcct ggtacgttgt
     6361 ataaaataat tggcaactta acgctatttg ctattgtttc aaagtgaagt ttaagacctt
     6421 tctcattagt cttattatag taaggagtta ttattaaaag accatccacc cctaattttt
     6481 cagcttcttg actcatatga acagacaaca tagtattgtt tgaaccagta cctgctataa
     6541 caggtattct cttattaact ttttcaactg tatattttat tacagcaaaa atttcagatt
     6601 cactcatagt agtcgcctca cctgttgttc cacaaacaac tagtgcatct gtgccattct
     6661 caatgtgata ttcgattaat tcacctaatt tttcaaagtt gacattatta tcctctgtaa
     6721 atggggtaac taaagcaaca gcagaacctt taaataacat ataatcaaat ctcctttttt
     6781 atctaaattt aattttttaa gtacaataat aattatagta caaattaatt aattttaata
     6841 ggtatagtta atatcttaac tgtttaaata agatatttat attatattaa tattagaaaa
     6901 atttt
//
LOCUS       DAEHWO010000132         6588 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEHWO010000132 DAEHWO010000000
VERSION     DAEHWO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.135"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            436..1710
                     /locus_tag="KNP54_003763"
     CDS             436..1710
                     /locus_tag="KNP54_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBF0894617.1"
                     /translation="MQFMDVSKYIEGANLKVKTKSGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPLLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1917..2234)
                     /gene="trxA"
                     /locus_tag="KNP54_003764"
     CDS             complement(1917..2234)
                     /gene="trxA"
                     /locus_tag="KNP54_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBF0894618.1"
                     /translation="MVKIVNNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2501..3253
                     /locus_tag="KNP54_003765"
     CDS             2501..3253
                     /locus_tag="KNP54_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBF0894619.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3240..4121
                     /locus_tag="KNP54_003766"
     CDS             3240..4121
                     /locus_tag="KNP54_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBF0894620.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDTSNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNNITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4347..5702)
                     /locus_tag="KNP54_003767"
     CDS             complement(4347..5702)
                     /locus_tag="KNP54_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBF0894621.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2538 a          949 c          824 g         2277 t
ORIGIN      
        1 aaaattatta tacttgcaca tcttttataa catataaaat ctttttttct aattatatac
       61 aatatatttt ccattatgtt ctaatcaatt tctttactat ttttacaact ttattagtca
      121 tattcataat tatttctaat tagtgtttaa cattttatgt aaaatttata aaaaaatgta
      181 tataaattaa aataagtgac tatactaaaa atatgatacg gataaacaat aagttcaacc
      241 tatctccccc aaaatcaagt gagctacagt ttcccccaac tgtagctcat tttcgtgtaa
      301 tttaataaac atctcaacaa gaattaatta acaaaacccc ttataaaaac ataacatata
      361 ttaaacaagc tcttgattaa aacttgagct tttttaataa aaaacagaat agtttattag
      421 ataaggggtt tttttatgca attcatggat gtatctaaat acattgaagg tgcaaacctt
      481 aaagttaaaa ctaaaagtgg tgaaactgtt aaaagaatat attttaacaa ctctgccact
      541 ccattagttt taaaaaacgt agtggataac ttaaactgtg agattccttt gcttacttat
      601 attaatgctc caggaataat ctcagaaaaa aatactttaa aatatgaaaa tgtacgctct
      661 actatcctca aacttattga tggagacgaa gaaaaggatt ctgttattta tgtcaaaaat
      721 gctacagaag gaataaactt cttagcaaaa ttttttaaag atgaaaatcc agataaattt
      781 gttattacca cagcaatgga gcatatggct aattacctgc cttttaaagt taattttcct
      841 acaaaagttg ttggaattac agaaaaagga gaacttgatt tatgtcaatt agagaatata
      901 cttaaaaatt atgctggtaa tgtatctctc gttacagtta caggagctag taatgtcaca
      961 ggtataacca ctcctatata tgaaatagca agaatagctc ataagtatgg tgcaaagata
     1021 ttggtggata ttgtgcaagt aattcagcat aaaccttttt caatgatgcc acatgaatgt
     1081 gatgagcata tagattttgt tgtttttagt gctcataaat gttattctcc actaaatgga
     1141 ggagctctgg taggacctaa aaaattcttt gaaaaattta atcctgtact atatggctca
     1201 ggttctacca aatttgtaaa tgataacaaa atactatatg caaacgtacc ccaacgtttt
     1261 gaagcaggat acccagagta ttttggaact cttgcaatgg gaaaagcact gaacacttta
     1321 aataaaattg gtctaaacag aatttcaaaa tacgaaagag aattattttt atatgctaaa
     1381 gaagaaatga gtaaaatacc taatataata atatatggag ataaatcaaa taatgtaatt
     1441 atcccaaata tatcttttaa tataagtaat atgtattaca aagatgtagc aaaatattta
     1501 gttgataact ttggaataga aactggagct ggagtagtag gtgcagatat ttatgtacaa
     1561 aaattattag gtataagtcc aaaagaagca tatgtcagat ttatgaggga aaatcctgta
     1621 ggtcttgtta ggataagctt aggaatgtac aatacttttg atgaggtgga tagctttata
     1681 catgctatta aaactttggc ttttaaataa gttttttcta ttctttttta tcaataaata
     1741 gagagtagtt ttgttttcac aaaaaagcaa attatatcaa cagtcaattt cattagcaat
     1801 tagacactca tttgtaacta tacaaactat tttacactat acaaacaaaa aactcattac
     1861 aatgagtttt tttgtttata tatgagattt attttaatta cttcaattta ctttaattac
     1921 atatatgatt caattttgtt ttttaaattc tccttaggca taaaacctat taatctatct
     1981 acaggttttc catccttaaa tattagcata gttggtactg tagatacttc aaatttctga
     2041 gctaattcta tactttggtc tatgtccacc ttcaagaagt ttgctttttc aaccatctca
     2101 tttcctaaag cttcatatat tggtgatagc atcttacaag gtccacacca agtcgcaaag
     2161 aaatctacaa ctactaaacc atctttattt tctacttcat ttataaattc attattattt
     2221 actattttta ccataatata catctccttt attatcttct tgatattaat atactacgac
     2281 ctatataaca gttcaattag gcactttttt gtaaccgcct atttttaata gatttaatat
     2341 tatgataaat agatttataa gattaaatat ttataagact aaatatttct aatatatttt
     2401 atttttttct taatatagtt gacatttttt cccttaaatt ataaaatcaa attaataact
     2461 acataggtag ttactaatct tttatcaaag gagtttctat atggataata ttattaatga
     2521 attacaaaat ataggattta ctaaatacga atctcaaata tacatatcat tattaaagga
     2581 aagcccttta acaggatatg aaataagtaa attatcaggt gtaccacaat caaaagtcta
     2641 tgaaaatata acaaagctat taaacaataa tataattatc aatgttggaa ctgaccctat
     2701 taagtacata ccaataaacc ctaatgaatt attaaaaaat aagaaaaaag aatttgacaa
     2761 ttctatggat aatctaaaga atagcttaca gatattaaat aaaagtaaaa gtgtagaata
     2821 cgtattaaac ataaaaggag ataaaaatat attaaaaaaa gcaatagaaa tgataaaaaa
     2881 tgcaaaacaa gaaattataa tttcttgccc ttatgaagaa attcttgaat taaaaaaaga
     2941 actcctaatt gcttacaaaa aaaatattaa tattgaaata ctacttttag aaaacaaaag
     3001 tctgaaaggt cttgataata ttcatattca tggaggtaat aaaactacac ttgaaaataa
     3061 aatgctttac aaaggaatta ttttgattgt agataatgat gaaatattga caggaaactt
     3121 atcagaaggc agtgaggcca tttcaatttg gacaaaaaac tctaacattt tatatattgg
     3181 agttcaatac ataaaacatg aaatttatat ttcagaacaa ataaaaggag gttataaaaa
     3241 tgaacaaaat taagattaaa caagttgatg cttttacaac tatacctttt ggtggaaatc
     3301 ctgctggtgt cgttactgat acctctaaca tttctgatga aattaagcag aatgtggcta
     3361 aagaaatgaa tttatcagaa actgcatttg tttcagagtc aaatattgca gattttaaag
     3421 tacaattttt cacaccaggt ttagaagttg atttatgtgg tcatgcaaca ataggtactt
     3481 tccatgcact tttggaagaa gggaagctta atactaataa aagtatattt tatcaagaaa
     3541 caaaagctgg tgtattatct gtagagctta agaaaataaa taatgaaaat atatttatga
     3601 tggaacagaa tacacctgaa tttgaaaatt tagataattg cagaaaagaa cttgcacaaa
     3661 tgataggtgt gcatgaagat agacttcttg aatatcctat tataaaggta aatactggac
     3721 tttggtggct tgtatttggt ctaaaatctt tagatgattt aaaaaatatc tctccagatt
     3781 taaataaaat caaaaaattt agtggtgata ataatataat tggtataact ccattttgta
     3841 tagaaactat agataaaaag tgtgactacc atttaagatc tatagcacca tatgttggag
     3901 ttacagaaga ccctgtatgt ggaactggga acgcttgcgt atcatcttat atagtacatc
     3961 acaatatttt agataaaact agttttattg gtgagcaagg taactttata aacagacctg
     4021 gaaaggtata tgtaaatata actagagaaa acaataacat aacttctgta aaaattggag
     4081 gaagtgctta tactgtctta agtggtgaaa ttatgtatta atcccatacc taataaaaac
     4141 aaataaaaat actagctaac taaagctagt atttttattt gttattttta tttaataatc
     4201 atactctaac aaatattata attatatata tcataatatt gtatttagaa gtaaaatttt
     4261 atttttatta ttaattagtt ataaatcaat ctaatacaac ataattacag tagattaacc
     4321 tataaaacat aataattgct tactgattat ttatcgtcct caacaagtct acttaatgtc
     4381 ttatcagata agaataataa tatcgctgca acaaatagta ttactggaat tatagtatat
     4441 actttaatca tatcaaattt aagagtaaat gcatatatat atccatatcc tttaccagct
     4501 ataaaagtag caaatgtcca tactcccata agaacaccta gaagcttctt aggtgcatac
     4561 ttacttacaa aagagttacc aagtggtgag aataacattt caccaagact taaaagaata
     4621 ccaaacatga ttatccatag tatactagct ttagcagttt caggagctcc aactcctctt
     4681 gaaaattctg caccaacaag cattaagaat gcaagaccta agaatattaa tccaagacct
     4741 gtctttttaa ataaactcat atctccttgt ggtctactag caagtttaaa ccataatgct
     4801 ccaagaactg gtcctaatac tatacataca agtgaattta atgagtcaaa ccaagcaaga
     4861 ggaacatcaa atcctccaac attcatgttt acaaatgctg caccataatc ataaactgca
     4921 agataagtta gataccagaa tacccagaaa attacagaga agaatgatat aagtataata
     4981 gcccaaattc tcttcttatc catgcttgta agaggagact tatctttttc ttcaattttt
     5041 tcagcaacta caccttcttt aaaaggtctc tttcctgcat tcccaaggaa tctccatcca
     5101 tatatgaacc atattgcacc tattacacaa agtacagctg ctataaagaa acattgagaa
     5161 aatccaagta caccattttt tgcaaatgtt ttaaggtaaa gaataccaac tgctatagta
     5221 ccaataaaag aacctatatt aacaaaagaa tattgtactg aaaatgctgt atcaagttct
     5281 tcttgactat caaaaagctg tccatttacc gcagatacgt tacctttaaa gaatgcagta
     5341 ccaattgaaa ctaagattat cattgcattt accatagaaa ctgtagttgc aatagaacca
     5401 agatagtatc ctacccccat gataagcata cctataggta tagtatatct agctcctatc
     5461 catctatctg atatataccc cccaattata ggtgcaaggt atgtgaatgc aacaaggttg
     5521 gcttgcatta tagcagcttg tcctttatct attccaagac caccatgaac tatagctgtt
     5581 gtaaggaata tatatattaa gtactttgaa gcataatatg ctgctctttc aaatgagaaa
     5641 gttgttgagc agatataaaa tcccatagga aatttaccct tcttttttac tgttgagctc
     5701 ataattttaa atcctttctt aattgtattt ttatttttta cgttttgtcc aaattctttc
     5761 ttttatgaaa gatataatat tattattttg taaaacaatt tgtaattatt attaagataa
     5821 ttgcgcattt atttgtagag tacatattct catggaataa aattaataca cttcttaatc
     5881 ataaatttaa attatataaa ttcactattt tcagatatag ttataaatta atatattctc
     5941 atctaatacc atgaaaaaac cttcgccata tgcaattctt attttttacg tgatagtatt
     6001 ttacaaacta aaatccccct tttgtagcaa cttatgtaat tacattttag tgctttttta
     6061 aaggagtctc gaataaagca acatatattt tgttcaaata atgtttttat ttatttttta
     6121 aatttatata ttacttcacc caaccaattc tcaacttaaa taactaaact actatctatt
     6181 cacagattag gcttatttct tacacattag tttataataa acactgtgaa tctaaacata
     6241 aaaactgtta ttttaaagta attacccata tattcgcttt gatactattt attgaggcta
     6301 tactctttat gtataatata ttatttataa aatacctcaa aatatattat tcataaaata
     6361 cctcaaactg aaaacttttt cacgaatatt tatttttcac ctcccctttt ttatttcacc
     6421 atgtaaatcg taccataaat atgcacttat atgcaagaaa aaaatctatt aatcgacagt
     6481 aaataattag aaaaattcaa attatattta tcaattatat tatataaaat atttcctatg
     6541 aaaatataaa ttaaattaat gttcagaata gtttttagat atgaaatc
//
LOCUS       DAEHWO010000133         6584 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEHWO010000133 DAEHWO010000000
VERSION     DAEHWO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.136"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(619..1179)
                     /locus_tag="KNP54_003768"
     CDS             complement(619..1179)
                     /locus_tag="KNP54_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBF0894622.1"
                     /translation="MLKKLKKMLLITCCLFMMSSTAFAETQNSEGKSFTISGYTFMYE
                     NAPQEIKDKYKENCLDIGVEPQPNDEIFITPSELKTYSNIDMYSARSSSFTVTYHYSY
                     YKVTGDKNYTVNTSTIVKYGNSGNPVHLVQLLLKKVGYALEVDSQFGNTTLSKVKSFQ
                     GSYGLTVDGIVGSATWKKFASATNLD"
     gene            complement(1225..2208)
                     /locus_tag="KNP54_003769"
     CDS             complement(1225..2208)
                     /locus_tag="KNP54_003769"
                     /inference="COORDINATES: protein motif:HMM:NF017390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBF0894623.1"
                     /translation="MSNLILTDILRTSITSSLVICFLLLLRTTIFRIFNKGFNYYIWL
                     IVIVRLLFPFSYFTYTISDSKFQYKPILNEVDYSNTVLIIYLTIVILLAIYRFIKYLK
                     FKSLVIDLSYDIENLEINNLYNNLLKELNIEKHIKLKYTYEINTPSFFGLFDNYILLP
                     PHNYNLNELHWILKHELIHYKSKDLYIRYLVLFLKCVYFFNPFIYLLDRIIYHSCELH
                     CDEVVLKGCSLENIKSYANTILDSIERSSRDSNNYTTGLHRKSNFEKRVYDMFKNKGK
                     SGILIALILCLLSSFTYFKFDSIISKPINHSLDAPLPVNTGKEKSFTITID"
     gene            complement(2221..2583)
                     /locus_tag="KNP54_003770"
     CDS             complement(2221..2583)
                     /locus_tag="KNP54_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0894624.1"
                     /translation="MIEKIPRAELKVMMLFWDTDKVLTSRDIVNIMSEEWKQTTTLTL
                     LSRLSKRGFLEPTKKPTHTTYKILIDKKSYLEFATSDFVKNVHNDSIVSLVDSVNKEK
                     IGKDELASLRAFIKKLKK"
     gene            3826..4473
                     /locus_tag="KNP54_003771"
     CDS             3826..4473
                     /locus_tag="KNP54_003771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894625.1"
                     /translation="MNKKLEKPFVYKREYDLTGYDVEILQKYELEQAIYVYVGSSCAY
                     NMRARSSKWRYHIRTNNKSICCNIKNFIHNLELFYKMELKLSDNIINDKLYYSNIAEF
                     EEFETLEKAREVESTIISQYQFLDSINHMLKQKIILLSNKDSVLNITKNGNTNYLKVK
                     NKYIEKHKNKPIMRYHINCQFNTDGSVKSITQEFEPILELNKKNTLSRPSRVFLK"
     gene            4748..6385
                     /locus_tag="KNP54_003772"
     CDS             4748..6385
                     /locus_tag="KNP54_003772"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894626.1"
                     /translation="MEQLDSKYKLKKFLMAVFRDGIGQGNNLIDNEYVRVFQNNKSNS
                     KQLELGEEFKEYSKTTFFKNIDDIVEFTFAKNIYYENTFFNLCTTDGKAGTNENLINR
                     YALGFDFDKKELGQGFNYKDIINLFTKIGLHYHILVDSGNGFHVYVLINKTNNIKLVS
                     EVTNTLINKLGADKQANLSTQVLRVPYTYNIKNTTKQVKIIHQDKNIYRYDIEKLAKK
                     YCKDVKTVGNTNTKYILDSKLPNCIVDILKNGSKDGHKNLDLQKIVVTLRLRNKSLSQ
                     VISVAREWNYISQNSLSNSELEYQVKYMYEKLKTVNFGCTGCEFNSDCWNKIESDFIY
                     SDEDTLFNMPHKHSKDLKYKNRKGVKIMTGNQLFIYNVLLNNKDRELNIDDIMELITY
                     KRKKKVKNIVMSEKTLRETLKELQHNDYITKTKGVTKLGIKDTYNVKEVRCNIDKQYT
                     ISYFVTMAVIWGIISTEELRLYTHMRYKQDLLVKDDKIKGNILRINQEELAKDLGVTQ
                     QRISNMIESLLDTKILDVWETKINDRGFMYYTYRLNK"
BASE COUNT         2683 a          692 c          917 g         2292 t
ORIGIN      
        1 ctaattagta ggtgcttttt taaaacaagt taaaaatcaa aaatagtatt agtaagcatt
       61 ggaaatgcta gattctaaaa tagaaaagta aaaaattggt gcactatcta aacttatcta
      121 tatcgctttt tccgtcgttt ggttctctag ttacgataca ggggatatgc ttatattgag
      181 ttatagtact aatcagtgct taatatagtt aataaaatta tagttaccat agtttagtaa
      241 ctatgatgta tgttagttag aaacttgcat ttcatgagtt gtaatatctt aaagtcagta
      301 gttttgattt taaaatatta attgcactgt tacaaatgac tttattaata aaaaattagg
      361 cagcttaaaa aaagtttaga ataaatttgc taggctttgc taagctattc ttttaaaaat
      421 aactttacaa aacaaacaaa taaggactta taaatataga taaaaaaaga aaattgaaaa
      481 ggattataga gacttacaag gctttaaata tatattctta attgtaaaat tatgtaatta
      541 aaatatttac tttattataa aaagacatga taaacttatt atcatgtctt ttgttaaact
      601 tatttatatg taaaaattct aatcaaggtt tgtagcagat gcaaattttt tccatgttgc
      661 actaccaaca attccatcta ccgttaagcc ataactgcct tgaaaacttt taactttgct
      721 aagtgtagtg ttcccaaatt gactgtctac ttctaaagca tatccaactt tttttaatag
      781 caattgtact aaatgaacag gatttcctga atttccgtat tttacaatcg tagaagtgtt
      841 gacagtatag tttttatctc cagtaacttt gtagtatgaa taatgataag ttactgtaaa
      901 tgaacttgac ctagctgaat acatgtctat gttgctataa gtttttaatt cactaggggt
      961 aataaaaatt tcatcattag gttgtggctc tacacctata tccaaacaat tttccttata
     1021 tttatctttt atttcttgtg gtgcattttc atacataaat gtgtaacccg aaatagtaaa
     1081 gctttttcct tcactatttt gtgtttctgc aaaagctgtg ctactcatca taaataaaca
     1141 acaagtaatt agcaacattt tttttaattt ttttaacata attcctccct ataattttga
     1201 atatatttga ataccagcaa atatttaatc tattgttata gtaaaagatt tttctttgcc
     1261 tgtattaact ggcaatggtg catctaagga gtgattaatt ggctttgata taattgaatc
     1321 aaatttaaaa tatgtaaatg atgacaataa gcataaaatc aatgctatta aaataccact
     1381 cttaccctta tttttaaaca tgtcataaac tcttttttca aaatttgatt ttctgtgtaa
     1441 tccagtagtg tagttatttg aatctcttga acttctttca attgaatcta aaattgtgtt
     1501 agcataactt tttatatttt caagggaaca accttttaat acaacttcat cacaatgtaa
     1561 ttcacagcta tgatatataa ttctatcaag tagataaata aaagggttaa agaaataaac
     1621 acactttaaa aataaaacca aatatctaat gtataaatct ttacttttgt aatgaattaa
     1681 ttcatgtttt agaatccaat gcagttcatt taaattataa ttgtgtggtg gcaaaagtat
     1741 ataattatca aataatccaa aaaatgaggg cgtattgatt tcataagtat attttagttt
     1801 aatgtgcttt tctatattta gttcttttaa taaattatta taaagattgt ttatttcaag
     1861 attttcaatg tcatatgata agtcaataac caaactctta aactttaaat attttataaa
     1921 cctataaatt gcaagtaaaa taacaattgt tagatatatt attaatactg tatttgaata
     1981 atcaacttca ttcaaaatag gtttgtattg aaatttagaa tcagaaatag tataagtaaa
     2041 ataagagaat ggaaaaagta atctaactat tacaattagc caaatataat aattaaaacc
     2101 cttattgaaa attctgaata tagttgtcct taaaagtagc agaaaacaaa taactagact
     2161 acttgtgata ctggttctta aaatatctgt tagaattaaa ttagacatat atagtaccta
     2221 ttatttctta agttttttta taaaagctct caaagatgcc aattcatctt ttcctatctt
     2281 ttctttatta actgaatcaa ctaaacttac aatagaatca ttatgtacat tctttacaaa
     2341 atcagatgtt gcaaattcta agtagctctt tttatcaatc aaaattttat aagtagtgtg
     2401 tgtaggtttt tttgtaggct ctaaaaaccc tcttttagaa agcctagata atagtgtaag
     2461 tgttgtcgtt tgtttccatt cttcactcat tatatttaca atatctcttg atgtcaatac
     2521 cttgtcagta tcccaaaata gcatcattac tttaagttca gcacgtggta ttttttctat
     2581 cataatatgt tcctccatcc taatgttaaa aaaattaata aatgtaattt tattctattg
     2641 aaatagagta ggacagtcaa ttgttttttg attaatgatt tacatatgta gagtaaatta
     2701 aaagaagtat atcacttgaa aagttttaca tacgtagagc atttttatca aatctcttaa
     2761 tttttttaat tgaattatat atgtgaatat aagagtaaat caacttaaaa catgcaaaaa
     2821 attaatattt actgacatgc aactgacaaa tcaacaaaaa taggaattga taaaataagt
     2881 gtatatattg aaattgctat aatacataca aaaatggcat aaaatactaa tttttatgtc
     2941 cttttctact gacatgtaaa aaagtcttgt aagtattgga attactagat tacataggtt
     3001 ttagatgcaa aattgtcgtt ttgtaaaaaa ggctactaaa atttataaaa acaattatta
     3061 attgatataa attatcacaa aaaaagacat ctatttctat gaaaaaaaaa ttttcgtctg
     3121 catgtaaaaa tagctatagt aatgcgtacg aatgttctat tattacagaa ttatttgtat
     3181 gtaaattata ttgaaaatat ctatcagaat tagaatttta tatggataaa acagaactat
     3241 caaataggag tatatagtaa agatttatat aatatgatga cctcgtacaa gcctgtaaga
     3301 gccgtttaaa agttgcttta gtattaatta tctttgaaaa tttaaaatag gtttaaatgg
     3361 cttgttaaat atgatgtatt actattatgt ataggggggt agttatgtag ttacatgttg
     3421 ttttaaaaaa taaatttaac tatagttctt tcacttccac attacaaaaa ataaattgag
     3481 tgtgtatgtt tttaagtaaa aatgatgttt aaatattgaa aaatagagat atagtgtatg
     3541 taaaatttag aatagtgtat gtaattttag gcataaaaat atgtgattaa accttaaaaa
     3601 ccaggaatat agtgtatgca tttttaaaaa taaaaattgt aacctttttg taatctttta
     3661 ttaaaatact tactttaagt ctaaaaatta ggggagatgt aaggatttgg gaaaaataga
     3721 agatgttata atcataaata tggtattcgt aggcttaaag tcaaaaagga ggtgaaatat
     3781 aaatagattt ttagctaaat taagtaagaa ataggaggag atttattgaa caaaaaatta
     3841 gaaaaaccat ttgtatataa gagagagtac gatttgactg gatatgatgt tgaaatttta
     3901 caaaaatatg agttagaaca agcaatatat gtttatgttg ggagtagttg tgcatataac
     3961 atgagagcta gaagtagtaa atggagatac catataagaa caaataataa gtctatatgt
     4021 tgtaacatta aaaattttat acataacttg gaattgtttt ataaaatgga attaaagttg
     4081 tcagataata ttattaatga taagctatac tatagcaata tagcagagtt tgaagaattt
     4141 gaaacactag aaaaagctag agaggtagaa agtactatta taagtcaata tcaattttta
     4201 gattctataa atcatatgtt aaaacaaaaa ataattttat tgagtaataa ggatagtgtg
     4261 ttaaacataa ctaaaaatgg aaatacaaat tatttgaaag taaaaaataa atacatagaa
     4321 aaacataaga acaagccaat aatgagatac catatcaact gtcaattcaa tacagatgga
     4381 agtgtcaaaa gtattacaca ggagtttgaa ccaatattgg aattaaacaa aaaaaatacc
     4441 ctaagccgac caagcagagt atttttaaaa taatatttta agataacaac aaaatgagat
     4501 aatactacta gacaatgaca actcaactac caattgagtt tatggagcta ccaactccaa
     4561 tatcggtcta actgattaag tatctgtagt tatataataa tattgctatc aattttagca
     4621 tcttaacaat attattatac atactaagct aaaattattc aatagttgta aaagttgatt
     4681 agtcaataag tatatattta atgtagtgtt atctcttaaa aaaactagat aaggagataa
     4741 taaatatatg gaacaattag attcaaaata taagttgaaa aaatttctaa tggcagtatt
     4801 tagagatggt ataggacaag gaaataatct tattgataat gaatatgtta gagtatttca
     4861 aaataataaa agtaatagta aacaattaga actcggagaa gaatttaaag aatatagtaa
     4921 aacaactttt tttaaaaata tagatgatat agtagaattt accttcgcaa aaaatattta
     4981 ttatgaaaat acatttttta acctatgtac aactgatgga aaagcaggaa ccaatgaaaa
     5041 cttaataaat agatatgcat taggatttga ttttgacaaa aaagaattag gacaaggttt
     5101 taattataaa gatataatta atttatttac taagatagga ttacattatc atatcctagt
     5161 tgatagtgga aatggattcc atgtttatgt gctaattaat aaaactaata acattaagtt
     5221 agtatcagaa gttacaaata cattaataaa taaattgggt gcagataaac aagcaaattt
     5281 atctactcaa gtattaagag taccttatac atataatatt aaaaatacta ctaaacaagt
     5341 aaaaataata caccaagaca aaaatatata tagatatgac atagaaaagt tagctaaaaa
     5401 atattgcaaa gatgtaaaaa cagtaggtaa tactaataca aaatatatat tagatagtaa
     5461 gctaccaaat tgtatagtag atattttaaa aaatggtagt aaagatggac ataaaaacct
     5521 agatttgcaa aaaatagttg tgactttaag attgaggaat aaaagtttaa gtcaagtaat
     5581 atccgttgct agagaatgga actatatatc acaaaatagt ctttcaaata gtgagctaga
     5641 atatcaagtc aagtatatgt atgagaagct taaaacggtt aattttggtt gtacaggttg
     5701 tgagtttaat agtgattgtt ggaataaaat agaatcagat tttatatata gtgatgaaga
     5761 tactttgttc aatatgccac ataagcactc aaaggatttg aaatataaga ataggaaagg
     5821 ggttaaaata atgactggta atcaattgtt tatctataat gtgttactta acaataaaga
     5881 tagagaatta aacatagacg atataatgga gctgataacc tataaacgta agaagaaagt
     5941 taaaaacatt gttatgagtg aaaagacatt aagagaaaca ttaaaagaac ttcaacataa
     6001 tgattatatt acaaaaacaa aaggtgttac aaagctagga ataaaagata catacaatgt
     6061 aaaagaagtt agatgtaata tagataaaca atatactatt agttactttg ttaccatggc
     6121 agtaatttgg ggaataattt caactgaaga attaagatta tatactcata tgagatataa
     6181 gcaagattta ttggtcaaag atgataaaat aaaaggaaat atattaagaa ttaatcaaga
     6241 ggaattagca aaagatttag gagtaacaca gcaaagaatt tcaaatatga tagaatcttt
     6301 attagatact aaaattttag atgtatggga aactaaaata aatgatagag gatttatgta
     6361 ctatacatat agattaaaca agtagatttt tgataggatt agaattgatt ttctagtcct
     6421 atttttatgc aaaaaaacta attaataaaa atttcttttg gtaaaataat tgtacgagaa
     6481 ttgcaaaaaa aaaatggcat caaagtattg aaattaagcc gttttaaaaa tttcttttgg
     6541 taaaataatt gtacatatat atgtagtata tatatatatg tttt
//
LOCUS       DAEHWO010000134         6525 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEHWO010000134 DAEHWO010000000
VERSION     DAEHWO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.137"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            220..1623
                     /locus_tag="KNP54_003773"
     CDS             220..1623
                     /locus_tag="KNP54_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBF0894627.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1714..1954
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1997..2695
                     /locus_tag="KNP54_003774"
     CDS             1997..2695
                     /locus_tag="KNP54_003774"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBF0894628.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2718..3719
                     /gene="trpS"
                     /locus_tag="KNP54_003775"
     CDS             2718..3719
                     /gene="trpS"
                     /locus_tag="KNP54_003775"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBF0894629.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4371..5938)
                     /locus_tag="KNP54_003776"
                     /pseudo
     CDS             complement(4371..5938)
                     /locus_tag="KNP54_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(5913..6056)
                     /locus_tag="KNP54_003777"
     CDS             complement(5913..6056)
                     /locus_tag="KNP54_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894630.1"
                     /translation="MYVYYFESPEKFAFNKVIRTKNQNEISLEKFNEFKETIQDKLLP
                     YNR"
     gene            complement(6274..6456)
                     /locus_tag="KNP54_003778"
     CDS             complement(6274..6456)
                     /locus_tag="KNP54_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894631.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
BASE COUNT         2314 a          775 c         1002 g         2434 t
ORIGIN      
        1 caattttaaa aatttagtat cattagaatt aaagtggtaa aacttttaaa tttatcattt
       61 ttaataagat ttgatttcaa agtatttaag gtttattatt aaaactgttt ttgaatatgc
      121 aaatattttg aaaaatatca gtttaataat aatgaatcta ttttattaat tttgaaatta
      181 aatttaaaat aattaataga gaggggaaat taaattagga tggaaaagaa aaaaataggc
      241 ctatggagtt tggtatttat gaatgtatca gctttatatg gtataagatg gatagctaaa
      301 tctacagcat caagctttgg tttaggatta ggtgcaatac ctatgtggtt attattctca
      361 tttatatact ttgtaccagg agctttaatt tgtgctgaat tagcttctac atatcaaaaa
      421 ggtgatggag gtctttacga ttgggttaag gaagcctttg gagaaaagta tggattttta
      481 gtttcttggt taaactggac agctaaaata ttttggtatt cttcattttt aactttctta
      541 gcagtaaatg tttcttatac aataggaaat ccagcccttg ctgataataa gatgtttgta
      601 cttatattat ctttaataat attctgggca ttatctctta tagcaactaa aggaataagt
      661 tttacaaaaa tatttactaa tacaggtgca ttaggttcaa caataccaag tgctatactt
      721 ataatatttt catttgtagc agtatttgtg ttgaaaaaac atgatatagc ttctacatac
      781 acaatagctt caatgactcc aaaacttaat atggatgcat ttgttgctat atcagctata
      841 atgtttggtt tagcaggagc agagactgct gctaacttca taacagaaat agataagcct
      901 gaaaagaact tccctaaggc aatattaata tcagctggaa tagtagcttc attatatgta
      961 ttaggttcaa ttgcaataac aatgataata ccaccagacc aaattactgc ttctaaaggt
     1021 gtattagatg cactttctgc tgtttgtgcg tctttaggaa ttggttcttg gttggttcaa
     1081 ttaatagctt ttggtatagc tttttcagta ttaggagcaa tagttcttta catagcatca
     1141 ccaataaaaa tgttatttgg tagtgttaaa aaaggaatat ttccagatag tttagtagag
     1201 gtaaatgaac acaagatacc ttctaaagca gttatacttc aagcaataat agttactata
     1261 atactattgg tgactacatt aatgccttct gttgatgcta tatacaatgt tcttgtaact
     1321 atgacagcat taactgcatt attcccatat gtattgttat atgcttctta tattaaacta
     1381 agaaaagaga gaccagatga aattagacct tatactatgg caaaatcaac aagtacttgc
     1441 ctaggtttag caaaaatggt tttagttgta actgtagtgg gtatattatt atctgcagca
     1501 ccagttatgc ctacatttgc tgaaaatgtt atatatgaga tagagatgat tggtggaggt
     1561 cttctagtta tattatctgg tctatggtta tggaatagat atgaaaagaa aacagctaaa
     1621 taaaatgtat tttaaaaatt tcttttggat attataatat atagttgaca atttatagtg
     1681 taaggaatat tataaaataa agaaattaat aaattaaatc ctgagataag aaatagtaaa
     1741 taaatatatt tttgcacaga gaattaagga tgctgagaac ttaataaaaa gtatttattg
     1801 aatgggtctt tgaggagtaa aatgaaatgt aatttaatat tacagagtat ttgatatcgt
     1861 gtatgcacgt tatagcatat attaagatat atatattcaa ttttgagtgt atataaattt
     1921 aggtggtacc acggaaaata tatccgtcct attgatttag gacggatttt ttaatataga
     1981 aaatttagga ggaaaaatga acgtaatagg aattataggt gcaatggatg aagaagttag
     2041 tattttagtt gatttaatgg atattagaga gactataaaa aaagctagct tagaatttta
     2101 taagggaatt ttggaaggta agaatgtagt gttagtaaag tgtggcatag gtaaggttaa
     2161 ctctgctctt tgtgcccaga tactaataag cgaatttaag gttgatgcta ttgttaatac
     2221 aggtgttgca ggagctttaa acgaaaaact tgatgttaat gatatagtaa tatcaactga
     2281 tgctatacag tatgatgtag acactacagc atttggagac cctaagggag ttataccaag
     2341 aatgaagact tctgtattta aagcagatga aagacttata gatgctgctt acaaatcttc
     2401 tgtggaagaa gtaaagactc ataaagtatt aaaaggaaga gtagttacag gagataaatt
     2461 tataaattct aaagaattaa aagaagaatt agtaaatgat tttggtggat attgtggaga
     2521 aatggaaggt ggagctatag ctcatgtatg ctatttaaat aatactccat ttgtaataat
     2581 aagagcaatg tctgataagg cagatggaag tgctgatgtt acttatgatg tatttgtaca
     2641 tgatgctgcc aataactcta aagacatagt tttaaatatg ttaaaatcaa tataaatata
     2701 taaggaggta caaaaaaatg agtgaaaaaa aagttatatt tagtggtgca cagccatcag
     2761 gcaaaatgac tttaggaaat tatttaggag ctataaaaaa ctggactgaa cttcaagaca
     2821 attatgattg ttattatagt atagttgatt tgcatgcaat aacagtacct caagacccta
     2881 aagttttaag agccaatact atagaattac ttgctcaata tatagcttgt ggattagacc
     2941 cagaaaaaaa tactatattt atacaatcac atgtcaaaga gcatgttgaa cttatgtggg
     3001 tattgaatac tatgacttat atgggtgaat taagtagaat gactcaattc aaagataaat
     3061 cacaaaagag tgaagcaaat ctaaatgcag gtttattcac atatccagtt cttatggctg
     3121 ctgacatatt gttgtatcaa actgacctag ttccagttgg agatgaccaa aaacaacatt
     3181 tagaattagc tcgtgattta gcaaatagat ttaataatag attttcacct acttttgtag
     3241 ttccagaagg atactaccca aaaggtggag caagagtgat gagtttgcaa gagccaacta
     3301 aaaaaatgag taaatccgat tcaaatgaaa atgcatttat actattagca gatgattcag
     3361 attctataaa gagaaagata aaaagaagtg ttactgattc tttaggtgtt gtaaaataca
     3421 atgatgaaca accaggtatt aaaaatctaa ttgatatata ttctaattta agtaaaaaga
     3481 gtgtagaaga gattgtaaac atgtatgaag gaaagggtta tggcatattt aaagaagatg
     3541 tggctgaagt agtatcagaa gctttaagac ctataagaga aaaatatgtt gaccttctta
     3601 ataataaaga ttatttagaa aaaatatata gtatgggagc agaaaaagcc gaaaaacaag
     3661 ctagaaaaac tcttagaaaa gtttataaaa aagttggatt tatagagaga agatactaat
     3721 tattagctat ctttacttga taaataaatt ttaaagttat taaaaaggta tatgatatga
     3781 aagagagagt ctcaaagtga acttttgttc atgaggcact cttttttgta tgaaataaaa
     3841 tatattttaa tcatttcaac aatgaaaaag aggattatct ctattttgag acagcatctt
     3901 ttgataataa aaaaagatga gcttttgctc atctcaaagg ggttagatta ttcttacttt
     3961 ggggaaagta gaataaaggt aaaagttaac tgatgtcaac tttgtctttt ttgcatatca
     4021 ctactgagca taaaaaaatc agaaaaccat agccttctga aacaacttct aacatacatt
     4081 gtattttata cccaatatgt aatttatgag ttaattttaa ctcttataat gaaaattgtc
     4141 aataatatat caaaaaaata ttttttaaat ttatataatt aaatgaattt atgtttatat
     4201 ataggtgata tgatacagat aattatcttt ttaatacaat atagttctaa aaaagaatat
     4261 attagaagaa gataatattt aaataaaaaa taccttataa agttaatttt ttaatacttt
     4321 ataaggtaaa tacatattgt attgtgggga taaatttaaa tcatttgata ctaatcaaca
     4381 ctaagaacca ataactctct atcatcttga gtaattgtat atattcttaa tttcttgtat
     4441 gtcataatat tttctccacc tgtaaaataa ctcctaagat taacacaatc agttttaggt
     4501 tgatttgtat ctcctaaata attacgcaat tctttatctt tagtttcaat atctttaaat
     4561 ccaaaatatt gtaaagtagc ttcaactcta tatttttgga cataatcgag agcttcttta
     4621 ttagtttatg ttggtgtaaa atacatacca tttatataag cctttattgt acttggatta
     4681 aatttaaaat ctgcagaata tattttatgt gtaactatta tttcttgaac agttggaatt
     4741 ttaacttctg gttcatcaag tatttcagga gtactattta gctctgtaat agataagtta
     4801 tctaagtata ttgtatcact atcaattaat gctatattta tattagaaga atctttttca
     4861 gtagtttcaa attcataact aaattttgta tatccttgtt ctagtaccaa ataatccgtt
     4921 ttttcttctt ttacttttat atttacaatt attgaattat atgttaaagg attttttgaa
     4981 ttttactaaa aacataacgt ttataaggtt ttagttcaga cataggtatt ttaatcttcg
     5041 tctcaccatt taatctattt gctgagcctt ttaaaccatc ttgatttgta gtattaacat
     5101 tactccatat actagggtaa ttattgtaat catcaaaatt agtaaagtaa gttggtgttt
     5161 ttataagtat attcattcct ctttcaagtt taacattaca tatttgttta tcagacaaag
     5221 tttttaaact gtctttaatc ttattgccta tattatcatc aaatatgagt tcaacacaac
     5281 tttcatctat tggtatatta ttaaaatata acaaaccatc ttttttagta gtgccaaaag
     5341 ttttttcaat tgcttctcca attgtaagtt caggtgtttt atcttctggg acctgtaaac
     5401 ttttagcagt aattcttctt ttgtaagatt cattttctgt atctaatata atagatacag
     5461 aaatactgtc aatttgacct atatcgtctt accaactatt tcattctgtt actatttgtc
     5521 cagaaccatt ttttgtacca aaatttccac ttacttgtgt tgtttctaat ttaatttgct
     5581 ttccatcatc taattttttt aattaattat aatttatagg aatcagtcta gaactaaatt
     5641 gatacattgt gttaagagcc ataggtgaaa atcctttttt gagataagta tttccaggag
     5701 atagattatt gccaatttga ttttcttgtg ctttgatagt tgataatgca tctccatcta
     5761 acactaaatt tgttgttggt gtcactttgt acataggtgc agtacctgtg ttgtagtatc
     5821 taatatttgc atttatatat gcagattctc ctttgtttat acttaatcca gtatttcatg
     5881 attatccatt gctattttga acagcagttg aattatctgt tgtatggtaa taatttgtct
     5941 tgtatagttt ctttaaactc attaaatttt tctaatgaaa tttcgttttg attttttgtt
     6001 cttattactt tattaaatgc aaatttttct ggagattcaa aataatatac atacataggt
     6061 ttatctattt tattttttga tatagcattt cgaagttctc tatattcttt ttctcaagaa
     6121 tttgcttcta tttgataatc ataaaaataa tttcttgtct gagaatattt gcttatctct
     6181 atagaatctt ttttatatga tcctaatact tctttttcag atttttcaag tttttgatct
     6241 tttctttctc attctttagc cttttcttta tctttaaaaa aatccttctg atctttctat
     6301 aggagccttg taagtagtat tacaaacttt tccactatag ctttgtaaat cttgtgcata
     6361 aatgttatta ggtaacaaac tacctaaagt tagatataat atcaacaata tagatataca
     6421 attactaata cttttatgtt tcctaaattt tttcatttat tctccctaca aatattagtt
     6481 tagttaactt ttgaatttta atttatttag attatataat ctaaa
//
LOCUS       DAEHWO010000135         6391 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEHWO010000135 DAEHWO010000000
VERSION     DAEHWO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6391
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.138"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(370..777)
                     /locus_tag="KNP54_003779"
     CDS             complement(370..777)
                     /locus_tag="KNP54_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894632.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1251..2135)
                     /locus_tag="KNP54_003780"
     CDS             complement(1251..2135)
                     /locus_tag="KNP54_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0894633.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2426..2902)
                     /locus_tag="KNP54_003781"
     CDS             complement(2426..2902)
                     /locus_tag="KNP54_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBF0894634.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3168..4343
                     /locus_tag="KNP54_003782"
     CDS             3168..4343
                     /locus_tag="KNP54_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBF0894635.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4424..5227)
                     /gene="proC"
                     /locus_tag="KNP54_003783"
     CDS             complement(4424..5227)
                     /gene="proC"
                     /locus_tag="KNP54_003783"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBF0894636.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5267..5851)
                     /locus_tag="KNP54_003784"
     CDS             complement(5267..5851)
                     /locus_tag="KNP54_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894637.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2107 a         1090 c          720 g         2474 t
ORIGIN      
        1 aagcacagac tatatcttat ccttcagcat tatccgttaa ggtctaccca cttccactac
       61 caatagcttg tagtgtactt ccctcaagag gaatagtcgt tgaagtttct cctattcgga
      121 gtttacctgc tgattgccca ttttaaagta cttaggattt aaccttatac catctaacca
      181 attttttcta ctttcgtaac tttcacactt aggtttattt catccttatg ttttagtttg
      241 attagcttta gggatttcca gcaattcaag tagtattgga taggttctat cctatctcta
      301 catataggtt tccctatatg ctgactattt tagctactaa ctcatgacta aagtcacgag
      361 tgtgcgtagc tattttttaa tcaatatttt agtaaatttt acggtaagta aaaacctctc
      421 tccttcaaat cctatagcaa atatacttac aagttgcttt gagaaaataa ctcctaatat
      481 agctacaact atgcatatac caactattat atttaaaaca ttgtttaaaa actttagtgc
      541 ttgcttttca ccttgtttac tacttatatc ttgatacatt ggaataaaag tagtaactat
      601 agcagtacct attgctgcaa atataatatt tggtatattc atagctgtta aataactctc
      661 tgtatataag cctgtaccat aaattgatga taatactaat tctctaccca ttccaagaat
      721 cttagagatt atagtaacta tcatcaaata aaaagttgct ttagctacct tgctcatttt
      781 atcactccac ttctaacata cctcttttta atcaagtaaa atttagctca ttagatataa
      841 ttctatcaac taatttgcct tgcttagccc tatcaaaata taattaacac ctatttctta
      901 atatatcaca aactacatta ttcttcatat ttttttattt ctccaataag ttttacattt
      961 ttcctatata aattgtatag cttcaattat attcaaagaa atggagttgc tacccgataa
     1021 ctttaaaagt aaaaaacaga ttttattatc tttttaaact atattctaac atattttgtc
     1081 catattgaga aattttacta aactattatg tactttatta aataaataaa ataacagcac
     1141 acctataaaa tacaagtgtg ctgttcataa acagatttta taaaaaaata attcctaagt
     1201 agagattaac atgctttctc atactctcat atataatgtg tctaaaaata ttaataaaaa
     1261 tgctttaatt gttttaactt acttggatgt cttaattttc ttattgcttt agcttctatc
     1321 tgtcttattc gttctctggt aactccaaat acctttccaa tctgttctag tgttttaggg
     1381 tcatcatcat caattccaaa tctcattctt aaaacttgct gttcttgctc tccaagacct
     1441 gtaagtagtt cttctatctt ttcttttaaa ttatgctgtt caacttcgtg tattacaaca
     1501 tctttaaaat cagcatctga tggtataaat tcaactaaac tactatcctc atcttctttt
     1561 aatggagtat ccaaagatac aacattttta tctcttctta ataattccaa cactttgtca
     1621 acttctaagc cacatgcatc tgcaatctca tctatagttg gctctcttaa taatacattt
     1681 aaaagttctt gtttcttttt ctttacaaaa tttattctct gatgaagatg tataggtatc
     1741 ctaatagtat tttcgcaatc gtcgatatat cttgttatac tttgttttat ccaccaagtt
     1801 gcataagtgc taaatttgta tcctttttta taatcgtact tttctacagc ttttataagt
     1861 cctatatttc ctgcttgaat taaatccaac atatcaatac tatctctttt atatctcttt
     1921 gctatgctca ctaccaacct ataatttgaa tttataaatt tttcttttgc tactgaagat
     1981 gagttgatta tttccttagc cagctctacc tcttctcctg ctgacaacat tttgtattcc
     2041 tctatttcct ttaaatacat tttcatcgca ttcgatacat ttgatgaacc cacacaaata
     2101 taattttcat aattattttc ttttttagta tccataatca aaccccttct attcatagaa
     2161 tttgctaaaa caaaaataaa taatttaaac ctacataatc tacaattaca taatatccca
     2221 ttctttaaat gaattgtttt gtatattatg tatacaaatt tataaaaact atacctataa
     2281 tattattcta cttctaacag caatatcctc cttatatata taatttattt tattatatgt
     2341 tgttatattc ttagtttttt gaatgatata tgtctaaaaa aagactgttt actaaacagt
     2401 ctttttttat atatatgctc aatatttaat tttcatgatg atgattacat ccacatccac
     2461 aattttcatc atggtgatga tgttcttcta aatcttttac ctgttgttcc atttcatgaa
     2521 actcttttac cattatatca taagttggaa gagctgcctc agtatcgtat tcttcccctc
     2581 tccaatcagc gtacatcata gcatctccat tagttaaaac caatctacct gacatagtta
     2641 tattatccac ttcttctaaa aattctattt gtttttgtaa aacttctcct tctaactcca
     2701 catcttcatc taaacattgc actatcatta caggtgcata ataatcttct tcatctttaa
     2761 catttacaac aatatctaaa attccttctg caccttcttc aaattctgcc aactcaacat
     2821 ttgtatcaat catatcttga ggtactaata aatcttctat taaatatttt attactctat
     2881 cttttactaa ttcttttgac atttattttt ctccttccga ttctataaca ttatcataat
     2941 catttctata ttatagtata ctacattaat tgttttttca atctcttaca aaaattattt
     3001 tttattatct tccttatatt ccctttttta ttacaaagtt gtaatcgcat tgatttaaaa
     3061 aatagtttat atttagtata atagaaatgt agcacatatt tttattcaat atattaataa
     3121 aaaaatatat tgaaaatgta atgtatgtta aatctaggag gaatattatg aagtttaaaa
     3181 aacaaattag ttctattgtt gtgtctacta tgcttgtact tgggagtatg aacctttctt
     3241 atgcagacgg tacaaatgta gttacacttg gagctaactt atcagagtct caaaagcagc
     3301 aaatgcttaa ttactttgga gtaaaaaaag accaagtctt agttttagat gtaacaaatg
     3361 cagaagaaag acagtattta caaggtgttg caacagaggg tcaacttgga aaagttacta
     3421 tctcttgctc atacgttgaa cctactaaaa aaggaaatgg aattaatgtt aaaacagcaa
     3481 acttaacttg ggtaactagt tcaatgattg cttcaaccct tacaacagct ggtcttgaag
     3541 atgcaaatgt tattgctgct gctccatatc ctgtaagtgg tactggagca ttgacaggaa
     3601 tcatgaaagc atttgaggat gcttcaggaa agaaacttga tgaaactaag aaagaaattg
     3661 cttctgaaga attggtagtt acaggtgact taggagatga tatagggcaa gaaaaagcaa
     3721 caggtgtaat gaatgatata aaaacagaaa ttgtaaagaa tggtacaaaa gataccaatc
     3781 aaatagcaaa tacaataaat aatgttgtaa ataattacaa tattactatt acaccagaac
     3841 aaaaagaaca aattaaaggt gtaatgaaaa aaatagctga ccaaaattac gattacaata
     3901 gcatgaaaaa tacactagat aatgtatcag ataatgtaaa tgaacaatta aagaaattag
     3961 gtgaaagtgt taagggttct ggtatactag atactattgg tggatggttt agtggaatag
     4021 gagactggtt ctctggttta ttctcaggcg gagataaaaa agatttggga atcttaaata
     4081 atactaatga tgagtctctt ggctctgatg ctgtaataaa ttctacagaa ggtgttcaaa
     4141 taaatccaca aaataatact aattctaaca atgatagtga tacaaatagc tcaaaaaatg
     4201 atacttcaag taataatgaa aataacgata gttctcaaac aaatgaaaac aacacaacaa
     4261 ataattcaga aaatcaatca aataataatg actcagttgg tttctttgaa aaaataaaaa
     4321 attggctttc aggcttattt tagaaattaa acaaataaaa agaattgcct aaaatggaaa
     4381 ttttctataa aaggcaattc tctttattta caataaattt ttattactca ctcatttttt
     4441 tagatttttc tatacatgca catattgctt ttatcacaga agctctaaaa ccttcttctt
     4501 caagtacttt aactgcttct atagtagttc caccaggtga acataccata tcttttaatt
     4561 caccaggatg ttttcctgtc tcaagtacca tttttgcaga acccataaca gcctgtgatg
     4621 caaacttata tgcttgtggt cttggcattc ctgcaattac tgctgcatct gctatagctt
     4681 ctataaataa aaatacatat gctggtgcag aaccacttgc accaattaca gcttctataa
     4741 gatactctgg tactacctca gtatttccaa aagaattaaa tacttctgta actgcttcta
     4801 agtcttcttt gtttatattt ttatttatcg aaagagaaga catggcttca tttacaagag
     4861 ctggagtatt tggcatagtt ctaactattt ttttatcttc tcctataata gactctatat
     4921 cttttataga ttttcctgct gctattgtaa ctataatttt attgtcatct ataaagtctt
     4981 ttatctcttc caaaatatca tcatatatat ctggtttaac agctacaatt actatatcag
     5041 aggttctagt tacttccttc gagtcttttg tagtatttat tccaaaattt gcatctattc
     5101 tatcgagagt tccttgacta tatgctgatg ctataaccat attaggttca actaattttg
     5161 aatttactat tccccctatc atagcgcttg ccatatttcc tgcacctatg aatccaattt
     5221 ttttcacttt agtacctcct tattgactaa tagtaatcgt taaaatttaa gcttctttaa
     5281 ctgcatcaga tttttcaaat ggatttggta tacttactac caaaattttc actaccttat
     5341 tagtatagtt gacccaatta tgattgttct tttcactatt atagtgtatt gtgtctcctg
     5401 gatacatttc tatttgttca tctcccaaaa acactgtaag agtaccctct aatacataca
     5461 caaattcctc accttcatgt acgtaacaac aaatttcctc actactctta cttggaagaa
     5521 tttcaattaa tcttggtagc attgtttttt cctttaaact agatgataaa tgataatgta
     5581 taaatgttga gttttctaca tcaaatactt ctttttcata acttcttaat acagctcttt
     5641 tatgctcttt tggcttcata aaaaagtaag ttaattctac atctagtaca cttgctattt
     5701 ttcctaagga atctgttgcc acacttgtta atcctctttc aagttgtgat aaaaaaccaa
     5761 ttgacaagtt tgttttttca ctcatatcct tcagcgtcat ttgcttttga gttctgagtt
     5821 gctttatttt tgctcctatg tccttattca aaaccatcac ccctaaataa ttttaatttt
     5881 ttcataatat aaatacaaaa atataaatat aggtactgaa cccatcttta tttcatttaa
     5941 aaaaattttt ataagtatta ctataattta tcaatctttt tttgtctaca tttttacgat
     6001 tatttacgat ttatttttca catatgtata tttaatcttg ccaactaaag atacattttt
     6061 tataagcatt tactctttat ataataaaac ttaagttgtt catgtagtct tcttctggtt
     6121 taattattaa aatttcaaat tatattatta tttctacaca ttattacatc ctttagtaca
     6181 attataacat aattttacaa tttaatgata tctattcaat gtcttttttt actctacaac
     6241 atattttatt ttagagttta atactatata tattttttat atacagcctt gtcatttttt
     6301 agattgtcaa gagttattga agtattttat gtagatttag attttatttc ctaatttctc
     6361 atttaacaag aattgcttat gataaaaaat a
//
LOCUS       DAEHWO010000136         6262 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEHWO010000136 DAEHWO010000000
VERSION     DAEHWO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6262
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.139"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            223..570
                     /locus_tag="KNP54_003785"
     CDS             223..570
                     /locus_tag="KNP54_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBF0894638.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(720..1220)
                     /locus_tag="KNP54_003786"
                     /pseudo
     CDS             complement(720..1220)
                     /locus_tag="KNP54_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(1247..2752)
                     /locus_tag="KNP54_003787"
     CDS             complement(1247..2752)
                     /locus_tag="KNP54_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBF0894639.1"
                     /translation="MNVAIYLRKSRADEEAEHRGEFETLSRHKTTLLKLAREQNLNVI
                     EIKEELVSGESIEYRPKMLELLGEIKNNNYDAVLVMDIDRLGRGNMQDQGLILDTFKK
                     SKTKIITPRKTYDLNDEFDEEYSEFEAFMARKELKLISRRMQRGKIKSIEEGKFIAQA
                     PPYGYDIKYLNNKERVLVINEDKATVVKIIFDMYLKGDGACKISNYLNELGYKTTTGR
                     TWYEKGIRDIIKNKVYCGYIVWNKVERKRNSSRTRGIEEQIEVKGKHEPIISEDIWNK
                     AQNIRKKRINSPTPNNKITNPLAGIVKCGYCNHTLIAKSNTTSNGYEKYMVCTNCKNK
                     ATKLYILENKILEVLNKWLVNYRLSLKDEKDNSKPENTLEHTLINLNKELDTLEKQKE
                     RLHDFLEQGIYDSNTFGERLKILLSRIENAREAINKTNIDIEMQKERNTVKTQIVPQL
                     EKILSEYTEEKEPYLKNILLKSVINYAVYKKEPNQKSDDFSLILYPNIPRD"
     gene            complement(2951..3805)
                     /locus_tag="KNP54_003788"
     CDS             complement(2951..3805)
                     /locus_tag="KNP54_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBF0894640.1"
                     /translation="MEWIERLNKAINYIEENITKEIEYEQVAKIACCSTYHFQRMFAY
                     MADVPLSEYIRRRRMSLAAVELQNDDKKIIDVALKYGYSSPTAFNRAFKSIHGVAPSV
                     IKKREITTLKAFPPISFKISIKGAEEMNYRIEKKEAFRIVGVSQPLHNELEKNFEIVP
                     QMWQKVALDGTLQKLIPMMDSQLQGVLGISICNNSEEWKYFISVSSTKSIDNTLEEYT
                     VPAFTWAIFSGEGQCPQAIQELEKRIVTEWLPTSGYEYDNGPDIELYLNPDPQNAKFE
                     VWIPVVKK"
     gene            4190..4471
                     /locus_tag="KNP54_003789"
     CDS             4190..4471
                     /locus_tag="KNP54_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894641.1"
                     /translation="MPNIEKDLDGTTTITYLNDDIGVPTDENGYKISMTILHGKTICH
                     VVSPETILGRKFTLEEKQEKDTIIYGAIEKIMVDRQLQIKNSNKEVASH"
     gene            4621..5469
                     /locus_tag="KNP54_003790"
     CDS             4621..5469
                     /locus_tag="KNP54_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HBF0894642.1"
                     /translation="MIKSFLMLGQSNMAGRGFISEVTPIYNERIQMLRNGRWQMMTEP
                     INYDRPVSGVSLAASFADAWCCENQEDRIGLIPCAEGGSSLDEWNIDGILFKHAISEA
                     KFAIQSSELTGILWHQGENDSNNGNYKFYYKKLLSIIETLRKELNIPDIPIIIGGLGD
                     FLGKVGFGKSCTEYVFINQELQKFAFEQDNCYFVTATGLTSNPDGIHIDAISQRKFGL
                     RYFEAFHKKKHIMEALANESELIIPSNSKTYTKTEKIYINSMDLALGKISYDEFESKL
                     IKLNDN"
     gene            5521..6042
                     /locus_tag="KNP54_003791"
     CDS             5521..6042
                     /locus_tag="KNP54_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003442791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894643.1"
                     /translation="MIPLLILGLLKQNPNSYGYELLALMEKKHYKYIVNFTKGSFYYN
                     LQQLEEKKFIEKVENKQSNKNRETHNYIITELGCQEFEKLMYKYGSKTEYINLSFYAT
                     LLFANDYKNEKLIELLETQIKQTQVRISLLNESIENDKTNSHYFNRMLENSRSHHLVN
                     IEWFEKLLNDIRD"
BASE COUNT         2232 a          857 c          822 g         2351 t
ORIGIN      
        1 atttatatta aagtttagat atctaaaaat acttttagaa tttattatat tatgttaatt
       61 ttttatatct tataagaatt gtatttttct aactataaaa atagtattat acttatattt
      121 aaaaataaaa gaattttatt cctattgtgt aaagtgagaa tactattttc ttatattggt
      181 ataataatag taaatctaat atagaaaaga ggtatttcta gtatgcatga aaataaaaaa
      241 aatctattag acggaagctt agctcaatat aatgatacag cagttccaaa aataccagta
      301 tttgctggta acgatataac ttcagaagtt tattatttta aacctaatca agttcttaat
      361 gctcatagac accctaatgg tgaacaaata tttgtgttcc taaaaggaga aggtaaaatg
      421 aaacttggtg agcatgaatg tgatgtaaaa aacggcgata ctgtatttgt accaacagga
      481 gagtggcatg aaattactaa tggaagcaat gaagaaatgg tagccgttca aattacaaaa
      541 attaatgctg gagcagaata cagaggatag atatataagt acagttagta ctttaatatc
      601 tattttatta tataaacttt aatctcaaat ataaaaagag tcttttaaaa ggctcttttt
      661 atatttttgt taattttcat tataaaaaca agaaaatatc tagctaaaac taatatattt
      721 tatttaatat tttttatagc attgtttgca aactcagtat ttacgatatc tttataaggt
      781 gcttccttat ctagttcttt agcttctttc ataacagtca tcaatttctt caaaccttcc
      841 tcttttaata caggattttg agaccatgca tctattgatt tatatctatc tacaactgtt
      901 gttaaatctt ctaaagatat atcttcaaag aaaggttgca tagccttagc tacttctttg
      961 ctagatgctt gttgaatcca taattgacct ttataaacag catttgtaaa tctttgaatt
     1021 aaatctttat tgtttttcat gtatgatctc gtagtagagt atgctgtaaa aggtatttct
     1081 ccagaatctt ttcctataga tgtaactata tatccactac cttctttttc cattgctgtt
     1141 gctgtaggtt caaatgctgt tgtaaagtca ccctctccac ctgcaaaagc tccagccatt
     1201 acaccaaatt ggtaatcagt ctatttataa catttaaaac atataattaa tctcttggga
     1261 tattagggta aagtattaaa gaaaaatcat cagatttttg attaggttct tttttataga
     1321 ctgcgtaatt tattacactt ttaagcaata tattttttag ataaggttct ttttcctctg
     1381 tatattcact taaaattttt tcaagttgag gaacaatttg tgttttaact gtatttcttt
     1441 ccttttgcat ttcaatatct atatttgttt tattaatagc ttctcttgca ttttctatac
     1501 gagataagag tatttttaaa cgttccccaa atgtattact gtcataaatt ccttgttcta
     1561 aaaaatcatg tagtcgttct ttttgttttt ctaaagtatc caattcttta tttaaattta
     1621 tcaaggtatg ttctaaagta ttttcaggtt tagagttgtc tttttcatct tttaaagata
     1681 gtctataatt tactaaccat ttatttaaga cctctaatat tttattttct aatatgtata
     1741 gtttagtagc tttattttta caattagtac aaaccatata tttctcatat ccatttgatg
     1801 tagtattaga tttggctatt aaagtatgat tacagtatcc acattttaca attccagcca
     1861 atggatttgt tattttattg tttggagtag gggaattaat acgttttttt cttatatttt
     1921 gtgccttatt ccatatgtct tcacttatta ttggttcatg ctttcctttt acctcaattt
     1981 gttcctcaat tcctcttgtt ctactagaat ttcttttcct ctcgacttta ttccatacta
     2041 tatatccaca atacactttg ttttttataa tatctcttat acccttttca taccaagttc
     2101 tacctgttgt ggtcttataa ccaagttcgt ttaaataatt ggatatttta catgcaccat
     2161 ctccttttaa atacatatca aagattattt taacaacagt tgctttatct tcatttatta
     2221 caagtactct ttctttatta tttaaatatt taatatcata cccataagga ggagcttgag
     2281 ctataaattt accctcttca atacttttga tttttcctct ttgcatacgt ctagatatta
     2341 attttaattc cttacgagcc ataaaagctt caaattcaga atactcctca tcaaactcat
     2401 catttaaatc atacgttttt ctaggagtaa taattttcgt tttagatttt ttaaatgtat
     2461 ctagtattaa cccttggtct tgcatattac cacgacccaa acggtcaata tccatcacta
     2521 aaacagcatc atagttatta tttttaattt cacctagtaa ttctagcatc ttaggtctat
     2581 attctatact ttccccagaa acaagttctt ctttaatttc aatgacattt aaattttgtt
     2641 ctcttgctag ttttaaaaga gttgtcttat gtctacttag agtttcaaat tcacctctat
     2701 gttctgcttc ttcatcagct ctgcttttgc gtaaataaat tgccacattc attaaatcac
     2761 accccttgaa tatattatat tcagtaacag attgattata tttaaaacac aaaaataaac
     2821 cttcaaaata caagatatat tttttaggtt tatttttata cagtaaattt tatagtatat
     2881 ttaaaagctt gtaatctaag taaatattta tactattaat tttatgcttt cttcattttt
     2941 taattttaaa ctattttttt actacaggta tccatacttc aaatttagca ttttgagggt
     3001 ctggatttaa gtacagttca atatcaggac cattatcata ttcataacca gaagtaggta
     3061 accattctgt tacaatacgc ttttctagtt cttgtattgc ttgtggacat tgtccttctc
     3121 cagaaaatat tgcccaagta aaagctggaa cagtgtattc ttctaatgta ttatctatag
     3181 attttgtact tgaaacagat ataaaatact tccattcttc tgaattatta caaatactta
     3241 tacctaatac accttgaagt tgactatcca tcatagggat taatttttga agcgttccat
     3301 ctaaagcaac cttttgccac atttggggaa caatttcaaa attcttttct agttcattat
     3361 gaagtggctg agatacacca actatacgaa atgcttcttt cttttcaatt ctataattca
     3421 tttcttcggc tcctttaata ctaattttaa aactgattgg aggaaaggct tttaaagttg
     3481 ttatttctct tttttttata actgatgggg caacaccatg aatactttta aatgcacgat
     3541 tgaatgctgt tggagaagag tatccatatt ttaaagccac atcaattatc tttttatcat
     3601 cattttgtaa ttctacagct gctaaagaca tccgtctacg acgaatatat tcagaaagtg
     3661 gtacatctgc catataagca aacattcttt gaaaatgata tgtagaacaa caagctattt
     3721 ttgccacttg ttcatactca atttcttttg ttatgttttc ttcaatatag ttaattgctt
     3781 tgtttaatct ttcaatccat tccataaaat cagctccttg taatttatat aatatctatt
     3841 ttaaaatagt taatcctctc tttctatgca ctaattaact agcttaataa agaatgaaca
     3901 tgagaaagtc tgtaattaac tacaaaaatg aacaaatagt attgtttttc acattaaagt
     3961 atatcacaaa ttagtatcta atttttatat aagataacag ttttaattta ttatgaaatt
     4021 tttataatat tttagcttag acatttaatt atatataaca ttttatttat agttaactat
     4081 ttttgaagtt tacccttaat caagcaacac ttagttattc aattataaat aatgattgag
     4141 aataggacaa tttttaagat acataaaata taaagaggag gggatttaaa tgccaaacat
     4201 agaaaaagac ttagatggta caactactat aacatacctc aacgacgata taggtgttcc
     4261 aacagacgag aatggatata aaatatctat gacaatacta catggaaaga caatctgcca
     4321 tgtagtatct cctgaaacaa tcttaggaag aaagttcaca ttagaagaaa aacaagaaaa
     4381 agatacaata atatatggag caatagaaaa aataatggta gacagacaat tacaaataaa
     4441 aaattcaaac aaagaagttg ctagtcatta gcacttcttt aataagtaaa gtaggacaag
     4501 tattttttat aatattattg acttatagtc taattagact ataatataaa catagatagt
     4561 ctaattagac tactattaaa aataaataca ataagaattt aagaaaggat aataataata
     4621 atgattaaat catttttaat gttaggacag tccaatatgg ctggaagagg attcataagt
     4681 gaagtgactc caatttataa tgaaagaata cagatgttac gtaatggaag atggcaaatg
     4741 atgacagaac ctattaatta tgacagacca gtttctgggg taagtcttgc tgcatcattt
     4801 gcagatgcat ggtgctgtga aaatcaagag gatagaattg ggctaattcc ttgtgctgag
     4861 ggaggcagtt ccttagatga atggaatata gatggtatac tttttaaaca tgctataagt
     4921 gaagctaaat ttgccataca aagcagtgaa ttgacaggaa ttttatggca tcagggagaa
     4981 aatgacagta ataatggcaa ctataaattt tattataaaa aattactttc tattattgaa
     5041 actcttagaa aagaattaaa tattccagat ataccaatta ttattggtgg attgggagac
     5101 ttcttaggaa aagtaggttt tggaaaaagt tgtactgagt atgtatttat caatcaagag
     5161 ttacagaaat ttgcttttga acaagataat tgttactttg ttacagcaac aggtcttaca
     5221 tctaatcctg atggtattca tattgatgca atatctcaaa gaaaatttgg attacgttat
     5281 tttgaagctt ttcataagaa aaagcatatt atggaagcat tagctaatga aagtgagttg
     5341 ataataccga gtaattccaa gacatataca aaaacagaaa aaatatatat aaatagtatg
     5401 gacttggcac taggaaagat atcatatgat gagtttgaat ctaaacttat taaacttaat
     5461 gataattaga taaaatattc attaatatac taataaatat agattgaaag aggtgatttt
     5521 ttgataccat tattaatttt aggattatta aaacaaaatc caaattctta tggatatgag
     5581 ttattagcat taatggaaaa gaagcattac aagtacatag taaatttcac taaaggttct
     5641 ttttattata atttacagca acttgaagaa aaaaagttta ttgaaaaagt tgaaaataaa
     5701 caatctaata aaaatagaga aactcataac tacataatta ctgaacttgg atgccaggaa
     5761 tttgaaaaat taatgtataa gtatggttct aaaacagagt atataaatct atcattttac
     5821 gcaacactat tatttgcaaa tgattataaa aatgaaaagt taatagaatt attggaaacg
     5881 caaattaagc aaactcaagt aagaatttct ctattaaatg aatccataga aaatgacaaa
     5941 acaaattcac attattttaa tagaatgcta gaaaattctc gttctcacca tttagttaat
     6001 attgaatggt ttgagaagtt gctaaatgat attagagatt gattttaata ataaaaaaac
     6061 atacatatat attttatata aatgtatgat atatagatta aaaataaggc agataatttt
     6121 caattgaata tctgtctttt tgttatataa gatgttaaaa gaaacttata ctatgtaagt
     6181 aaaatttata aatataaagt tgttcattgt tgaattacag acacttaaga tgaaaagtat
     6241 gacatttgat ataataaaat tg
//
LOCUS       DAEHWO010000137         6257 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEHWO010000137 DAEHWO010000000
VERSION     DAEHWO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.140"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(145..567)
                     /locus_tag="KNP54_003792"
     CDS             complement(145..567)
                     /locus_tag="KNP54_003792"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894644.1"
                     /translation="MDNKFNEVITKYEVKKKQFLNTRVDSFTIKDIEILLNEIEILNS
                     EITKTNDTIDTLNKNIKYLKYLNKKAKNIIKIYREELEEFKTKAFIPKRKKQQITQKD
                     IDKIKKLSQDGLSYSKIQKITKWSKCTISKVINGYYDK"
     gene            complement(668..2521)
                     /locus_tag="KNP54_003793"
     CDS             complement(668..2521)
                     /locus_tag="KNP54_003793"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012493.1,HMM:NF016724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBF0894645.1"
                     /translation="MEKLNLEWVTDIIGEDYKKWNMEDRHIINNRNNVFIETQTGTGK
                     TKFIIDKIVPLVNQSIRNKRKLNLLIICNRINLKRQVKLELLKSNLDLYEFDKDIKKI
                     CNSDNTENNIKETFQILDKLSKITNGITIMSYQQLGEIIYYNNFYCNQHKNNLNFFDF
                     IVFDECHFMLSDLEFNTKCNLIFNELVLKEYSNSFRIFLSATLYELKNAIDFNARLEN
                     SRGEARKNNCNFNIYTFFNQYISLNHTNNFKEKTNLNNEYEFSTGRDYSYLDVKYFKN
                     IEDIIILLKNHFSANKDKWLIFVSKIKDAQYIKERLKSEKISIEIFKSGSNTKEAENI
                     VHNSSFECDVLISTKVLDNGINLKDKSIRNLVVMELDKTTFIQEIGRIRVDIKNPHKI
                     NLFIPMKNKKTFSFLKRRYDYKVKKIEKFSNSTTEFYREHNLNFQSVPQELFYLYGYA
                     NTQLIWAINPLGLYKLAESIKFTDEMIKKFTGEPKVIEHSKNVKVNNPNPTPPDNFAF
                     VKKQLEWLGLENTFNEANLINLDSEIVDSKEITILKNYLDKNLDKKLYKDEQQELSNF
                     ITEELKTVYTKKDYRTKKLNLKTINKILLENNLLYKIERSKGCSYWIIYKS"
     gene            complement(2690..3262)
                     /locus_tag="KNP54_003794"
     CDS             complement(2690..3262)
                     /locus_tag="KNP54_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBF0894646.1"
                     /translation="MSTTRPLEVEEYNQILNLLDTGFTYTNDDGKQKIFRPNIKVKLA
                     LILEANLGLRISDILRLQVKNFKNDKLEITEKKTDKLQYRDINSAITNLIKDYAILNK
                     LSPNDFLIDIGERAIQKQLKIMCNFLNIQNISTHSFRKMYATQQFKNNNNNLYLVKEL
                     LNHTSIATTQRYIRVSQKDIDKASKDFLLI"
     gene            4006..4290
                     /locus_tag="KNP54_003795"
     CDS             4006..4290
                     /locus_tag="KNP54_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBF0894647.1"
                     /translation="MAGYRDNWFDNNDSKHGWYTCVRCGKKLRKGNVDIDHIIPQKYG
                     GKDNLNNLQCMCKSCNRSKKDSLNNTVTDYSKNTIKNTKKTLDGLFKKLK"
     gene            complement(4611..5471)
                     /locus_tag="KNP54_003796"
     CDS             complement(4611..5471)
                     /locus_tag="KNP54_003796"
                     /inference="COORDINATES: protein motif:HMM:NF013235.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBF0894648.1"
                     /translation="MKNEYIIKKSNYFIMNCKYDLSIQEQRIILTLASMIKPTDEEFK
                     EYKFSTKEFKELLNLKGQSAYSEIPKITKKLLGKIIEIEEENEIIQCAWISTAKHLKK
                     EGVIILKIASDLKPYMLQLNTLYTSYKLKNVLSMKSKYSIRIYEILKCHEFKQQGFID
                     ISILELRKLLKAEHIYPKYANFKQKILEVVKTELEEQTDISFEYEEFKTGRTITNLRI
                     FINKKDVIVNNFKEECVTKVKEQTKTKKIIGDMPRQKTKFHNFNETFTQYTNDELDDI
                     IKKSQKEKFK"
BASE COUNT         2192 a          753 c          654 g         2658 t
ORIGIN      
        1 aaaaaaaaca agcttcaaaa ggctttttag aagcttgttc actccttaga ttgatttcat
       61 gtatgcttaa ggtaaatcca ttaagaccac tcataaaaac cttctaaaaa gccttttgaa
      121 gcttgtagga tatgattaag tacattactt atcataataa ccatttatta cttttgaaat
      181 agtacatttt gaccattttg ttattttttg tatttttgaa tagcttaaac catcttgtga
      241 taacttttta atcttgtcaa tatctttttg tgttatttgt tgtttttttc tttttggtat
      301 aaaagcttta gtcttaaatt cctctaattc ttctctatat attttaataa tgttttttgc
      361 ttttttattt agatatttta aatactttat atttttattc aaggtatcta tagtgtcatt
      421 tgtttttgta atttcactat ttagaatttc aatttcatta agtaatattt ctatatcttt
      481 aatagtaaaa ctatccactc tggtatttaa aaattgcttt tttttaactt catatttagt
      541 tataacttca ttaaatttat tgtccatatt gcaacctcca aaaatcgtta tttattaatt
      601 acgtaactag aataacaaat aacaaatgag attacaaatt taattttttt aaacttgaat
      661 atataagtta agacttgtat attatccaat aactacaacc ttttgacctt tcaattttat
      721 ataaaagatt attctctaat aaaatcttat ttatagtttt cagatttaat tttttagtcc
      781 tataatcttt tttagtatag acagttttca actcttctgt tataaaatta gatagttctt
      841 gttgctcatc tttataaagt tttttatcaa gatttttatc aagataattt tttaatatag
      901 taatttcttt tgaatcaact atttcactat ctaaatttat taagttagct tcattgaagg
      961 tattttctag ccctaaccat tctaattgtt tttttacaaa agcaaagtta tctggtggtg
     1021 ttgggtttgg attattgact tttacatttt tgctatgctc tataacttta ggctctccag
     1081 taaatttttt aatcatttca tcagtaaatt ttatagattc agctaactta tacaatccta
     1141 gagggttaat tgcccaaatt aattgagtat ttgcatatcc atataaataa aataattctt
     1201 gtggaactga ttgaaaattt aaattgtgtt ctctataaaa ttcagttgtt gaatttgaaa
     1261 atttttctat ctttttcact ttataatcat atcttctttt taaaaatgaa aatgtctttt
     1321 tatttttcat aggaataaat aagtttattt tatgaggatt tttaatgtct actctaattc
     1381 taccaatttc ttgaataaat gtagttttgt caagttccat gactactaaa ttcctaatac
     1441 tcttgtcttt taaattaatt ccattgtcta atactttagt tgatatgagt acatcacatt
     1501 caaaactgga gttatgtact atattctctg cttccttagt gtttgaacca ctcttgaata
     1561 tttcaatgct tattttttca ctttttaaac gctcttttat atactgtgca tctttaattt
     1621 tagaaacaaa aataagccat ttatctttat ttgctgaaaa atgatttttt aaaagaataa
     1681 taatatcttc aatattttta aaatatttta catctaaata actataatct ctaccagtag
     1741 aaaactcata ctcattattt aaatttgttt tttctttaaa attatttgta tgattaagag
     1801 aaatgtattg attaaaaaaa gtataaatgt tgaaattaca attatttttc cttgcttctc
     1861 cccttgaatt ttctaagcga gcattaaaat ctattgcatt tttaagttca tataatgttg
     1921 cacttagaaa tattctaaat gagttactat attcttttaa aactaactca ttgaatataa
     1981 ggttacattt tgtattgaac tctaaatctg ataacataaa atgacattca tcaaaaacta
     2041 tgaaatcaaa gaaatttaga ttatttttgt gttgattaca gtaaaaatta ttataatata
     2101 taatttcccc taactgttga tatgacataa ttgtaatgcc atttgttatc tttgacagct
     2161 tatctaaaat ttgaaatgtt tctttaatat tattttcagt attatcacta ttacaaattt
     2221 ttttaatgtc cttatcaaat tcatataaat ctaaatttga ttttaatagt tctagtttta
     2281 cttgtctttt caaattaatt ctattgcaga taattaaaag atttaatttt cttttgtttc
     2341 ttatactttg attaactagt gggacaattt tatcaattat aaattttgtt ttgccagttc
     2401 cagtttgtgt ttcaataaaa acgttatttc tattatttat aatatgtcta tcttccatat
     2461 tccatttttt ataatcttct ccaataatat ctgtaaccca ttctaaattt aatttttcca
     2521 ttatataaac tccatgattt taataattat ttgcaaatga tatgataatg ataatcctat
     2581 aaaaattaat aaataataaa tatagtatat attcaaattc atattactat ttcactatat
     2641 catagagatt attatttttg aaaaattacc taaaaaatat ctgaaatatt taaatcagta
     2701 aaaaatcttt agaagcttta tctatatctt tttgtgatac tcttatgtat ctttgtgtag
     2761 ttgctattga tgtatgattt aataactctt ttactaaata tagattatta ttattatttt
     2821 taaattgttg agtagcatac attttcctaa aactatgtgt tgatatattt tgaatattaa
     2881 gaaaattgca cattatcttt aattgttttt gaattgctct ctccccaata tcaattaaaa
     2941 aatcatttgg agatagttta tttaaaatag catagtcctt gattaaattt gttatagctg
     3001 aattaatatc tctgtattgt aacttatctg ttttcttctc tgtgatttct aacttatcat
     3061 ttttaaagtt tttgacttgt aatcttaaaa tatctgatat tcttaaccct aaattagctt
     3121 ctaatatcaa agccaattta acttttatat ttggtctaaa tattttttgt tttccatcat
     3181 cattggtata tgtaaatcca gtatccaaca aattcaaaat ttgattatat tcttcaactt
     3241 ctagtggtct tgttgtagac atttttaaaa cctccataat agataaatat tttatataat
     3301 aatactatta tagcacagta gttcgtgttt tatgataaat aagttcgtat tattgtttgc
     3361 ttatttttaa atttttttga aagtattgca attactaaaa ttcctgcaat agttcgtgtt
     3421 ttatagaaaa tacgaactat ttagttttgc aatttttttg gcatcataca cctaaaaatt
     3481 ataatctcta tacctatttt ctatactgca aggaatagaa aagggaggtg tatatatgct
     3541 taaaataata ataagattag tgttattatt agtcgagata tatttatatt taagataata
     3601 ttttaaaaca tattttatat tttaaaataa aagtctaaag gtgtcggaac atcataataa
     3661 aatttattat tatatttata tacatttttc ataaatgtat tcgttcctca tgtgtcggtt
     3721 taagggaggg tatgtctttt ttaaaaaaag acttttttat aataaatttt actatagtaa
     3781 ttttcttagt aaccaaaata gattttgaat taaatatagt aattattact atatctatca
     3841 tatttcctgt atataattaa ttaaaattaa gttactacta gaaacaataa gagtattttg
     3901 tataatgtat atcaaattac tatagtagat tttaagatat ttagaggtaa atactgaata
     3961 tttgtctaat tatatttaaa aaataaaaag taggtgaata aaataatggc aggatataga
     4021 gataactggt ttgataataa tgattcaaag catggttggt atacatgtgt tagatgtggt
     4081 aagaagttaa gaaaaggtaa tgtagacata gaccatataa taccacaaaa atatggtggt
     4141 aaagataatt taaataactt acaatgtatg tgtaaaagtt gtaatcgttc aaaaaaagac
     4201 agtttaaata atactgtaac ggattacagt aagaatacaa taaaaaacac taagaaaaca
     4261 ttagatggct tattcaaaaa actaaaatag agatactcaa atgagtatct ctattttagt
     4321 tttttattgt taaattttat aaaaatctta ttctataggt ttaataattt cttcaagatt
     4381 gcctaactta taaccaaaat tatcatctga tttattttca attttgacta ccattaatat
     4441 tttaatttga ctctaaatct ttaatcaatt ctacatttga cttttcaatt tcattcaaaa
     4501 tagatgtatc tgcacttata ccttctttat caaattgatt agatacaatt tgatacatgt
     4561 ttttatataa aaaatacgaa aatatggcta actaacttag taagttagat ttacttaaat
     4621 ttttcttttt gactcttttt gattatgtca tctagttcat catttgtata ttgagtaaat
     4681 gtttcattaa agttgtgaaa tttagttttt tgtctaggca tatcaccaat tattttttta
     4741 gttttagttt gttctttaac ctttgtaaca cattcttctt taaaattatt tactataaca
     4801 tcttttttat ttataaaaat tctcaaattt gttatagttc ttccagtttt aaattcttca
     4861 tactcaaagc taatatctgt ttgttcttct aattctgtct ttacaacttc aagtattttt
     4921 tgtttaaagt ttgcatattt aggatagata tgttctgctt tcaataattt tcttaattcc
     4981 aaaatactaa tatcaataaa accttgttgt ttaaactcat ggcattttag tatttcataa
     5041 attctgattg agtacttact tttcattgat aaaacatttt ttagtttata gcttgtatat
     5101 aatgtgttta attgtagcat gtaaggcttt aaatcggatg ctatttttaa tataataaca
     5161 ccttcttttt ttaagtgttt agccgtagaa atccatgcac attgtattat ttcattctct
     5221 tcttcaattt caataatttt tccaagcagt ttttttgtta tctttggtat ttcagaatat
     5281 gcagattgtc cttttaaatt taataattcc ttaaattcct ttgtactaaa tttatattct
     5341 ttaaattctt catctgtagg ttttatcatg gatgctaatg tcaaaattat tctttgttct
     5401 tgtatagata aatcgtattt acaattcatt ataaaataat tagatttctt aattatgtac
     5461 tcatttttca tacatacacc cctataaaat tataatctat aactataacc tagtaaagtt
     5521 atagttagca ccaaaaaagt tatatttcgc accaaaaaag ttatatttcg caccaaaaaa
     5581 gttatatttc acaccaaaaa agttatattt cacaccaaaa aagttatact tagaaaatat
     5641 ggacaagtaa ttccaacggt ttaatacccc tctaaaatag tttaaaataa ttaaaatatt
     5701 tatttaaaat aataaaagac aaaaaataaa aaataaaaag aaggattttt ttagtgcaaa
     5761 tggaaattat acagtaccca aattaaaaaa cattaaaaga catttataag tttgacaata
     5821 ttctataaaa actcataagg ggtgaatagg atgacaccta aagttttaga catgtttata
     5881 acgaacaaca tttataggtt tgaaagttgt ttttttctag ttgttaattg ttaaatacaa
     5941 ctttcagact tattatttaa atataaattt gaagaagcta taataaatca taattttata
     6001 agactatttt caatatacat aaacctatat tgttactaaa taccccatag aatcatttct
     6061 aaggggtatt tatacgttta tgtcaatata atgcataaat caagtttaaa cgcttctgga
     6121 agccatttaa atggcttaga atagcatagg aatgtgtttg taaaagttgg aaattttaat
     6181 tgcatattat caataaaagt aaatatctta tatagaatat atgtttgcaa cataatatta
     6241 cttataatca aggacat
//
LOCUS       DAEHWO010000138         6176 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEHWO010000138 DAEHWO010000000
VERSION     DAEHWO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6176
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.141"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            178..1200
                     /locus_tag="KNP54_003797"
     CDS             178..1200
                     /locus_tag="KNP54_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBF0894649.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            1260..2267
                     /gene="gap"
                     /locus_tag="KNP54_003798"
     CDS             1260..2267
                     /gene="gap"
                     /locus_tag="KNP54_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBF0894650.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2489..3691
                     /locus_tag="KNP54_003799"
     CDS             2489..3691
                     /locus_tag="KNP54_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBF0894651.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3717..4460
                     /locus_tag="KNP54_003800"
     CDS             3717..4460
                     /locus_tag="KNP54_003800"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBF0894652.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4469..6001
                     /locus_tag="KNP54_003801"
     CDS             4469..6001
                     /locus_tag="KNP54_003801"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBF0894653.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTILDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         2455 a          728 c         1247 g         1746 t
ORIGIN      
        1 aaaatactgt gatttgaaaa tggtggagaa atattttata aaataaaaaa ataaaaaagt
       61 ttttgaaaaa ctattgaaat ctatacgcaa atcctataaa ataaaaatat cttgtgggac
      121 ttaaataaac actagggaca aaaaaagtcc cgaaaggaaa gcaataagga gtatgttatg
      181 aagaacttat tagaaattca aaagaaattg attccacagg caattgaact tatggaaaga
      241 agatactcta ttttaagaca aatatcttta agtgaaccaa taggtaggag aacattatca
      301 aatgtattag agattagtga aagaataatc aggtcagaaa ctgagttttt aaaagaacaa
      361 ggacttatag acgtagctgt atctgggatg actatcacta aagaaggttc tgatttgtta
      421 gataaactta aggacatcat gagtgacatc atgggattgt ctaagttaca agatagagtc
      481 agagaaaagc ttggaataaa aagggtaata ttagttcctg gaagctgtga tgaaaatgga
      541 agtttactaa aagatgtaac tagatatgga tgcgaatatt tcttaggcat tttaaaagat
      601 ggagatatcg tttcaataac aggaggaagc actatgttgg agttttcaaa cgttattaaa
      661 actgataaga gatatccaaa ctctacaata gttccagcta gaggaagtat gggaactgat
      721 gtagagatgc aatctaacaa tatagttgct tcaataagta agaaattaca ttctaattgc
      781 aaacttttac atataccaga tgagttggat gaaagtgcaa tgaaaactct tagccaagtg
      841 ccagagatta agacaacttt ggagtatatt aaaagaacag acattttagt ttttagtata
      901 ggtagagcag atgtcatggc aaagagaaga aaacttccag aagacaaggt tgatgagata
      961 ttatctaaaa atgcagttgg agaagcattt ggatattatt tcaacaaaga tggagaaata
     1021 gtttacaaac tgaacactgt tggaattgat ttagaaacag ttaaacaagt aaaagaaact
     1081 attgcaatct ttgcagggac tgaaaaagta gaagccttat tagctatatc aaatatgcat
     1141 aaaaacatgg ttcttgtaac agatgaagaa agtgcttata agatattgtc attattataa
     1201 aagtcaagac ctagcacaga gctagaaaac atacatttac tttataggag gtagcgaaaa
     1261 tggttaaagt agctataaat ggatttggaa gaataggaag attagcatta agaaaaatga
     1321 tggagcaaca agataagttc gaagttgttg caataaacga cttaacagac gctaaaatgt
     1381 tagctcattt atttaaatat gatacagctc aaggaagatt taacggagaa atagaagtta
     1441 aagaaggtgc ttttgtagta aacggaaaag aaataaaagt aacagcagaa agaaatcctg
     1501 ctgacctacc atgggctgaa ttaggagtag atatagtatt agaatgtaca ggattcttta
     1561 catctaaaga taaagctgaa gctcatatac aagcaggggc taagaaagtt gttatatctg
     1621 caccagctac tggagattta aaaacaatag tattcaacac aaacagtgac atattagatg
     1681 gttctgaaac agttatatca ggagcttctt gtactactaa ctgtttagct ccaatggcta
     1741 aagtattaaa tgataaatac ggtatagaaa aaggcttaat gactactata catgcataca
     1801 ctaatgacca aaatacttta gatggtcctc atccaaaagg tgatttaaga agagctagag
     1861 ctgctgctgg aaacatagtt ccaaacacta caggagctgc aaaagcaata ggcttagtaa
     1921 taccttcatt aaaaggaaaa ttagatgggg cagcacaaag agtaccagtt gtaactggtt
     1981 caataactga attagtttgt acattaggaa aaaatgttac agttgaagaa ataaatgcag
     2041 ctatgaaaga agcttcaaac gaatctttcg gatatactga agaaatgtta gtatcttctg
     2101 acataatcgg aataagctac ggttcattat ttgacgctac tcaaacaaaa gttatggaag
     2161 tagatggaaa acaattagtt aaagttgttt cttggtatga taatgaaatg tcttatactt
     2221 ctcaattaat aagaacttta ggatactttg cacaattagc aaaatagtca gttttgagaa
     2281 aatagaaaag tagattgaca aagtccgagt ttgtagttta atactacgga ctcaggactt
     2341 tttttaagaa aaaatatata aaatacacct aaataatgtt acatactata tataaaaata
     2401 tgataatatg atatatttaa tagggtaaaa gtatgtacta tattatactt ggcaataaaa
     2461 aattacttta ttaaaaggag agatatttat gtcaatgctt aacaaaaaaa ctatagaaga
     2521 tattgatgtg tgcggaaaaa aagtattagt aagatgtgac tttaatgtgc cattacaaga
     2581 tggtgtaatt actgatgaaa atagattgaa cggagcttta ccaactattc aatatttaat
     2641 ttctaaaggg gcaaaagtta tattatgctc tcacttagga aagccaaaag gagaagctaa
     2701 accagaatta tctttagcac cagtagcaaa gagattatct gagatgttag gaaaagaagt
     2761 tgtatttgca gcagacgata atgttgtagg agaaaatgca aagaaagcaa ctgaaaaaat
     2821 ggaaaacgga gatgtagtat tattagaaaa tactagatat agaaaagaag aaactaaaaa
     2881 cgaagagaat ttctctaaag aactagcatc acttgctgaa atatttgtaa atgatgcatt
     2941 tggaactgct catagagcac attgctcaac agttggtgca ggcgagtttt tacaagagag
     3001 agtttgtgga tacttaattc aaaaagaatt aaaattctta ggagaagctg ttgcaaaccc
     3061 tgtaagacca tttacagcta tacttggagg agctaaagtt tctgataaat tagctgttat
     3121 aaacgaatta ttagaaaaag ttgataatct aataataggt ggaggaatgg cttatacatt
     3181 cttaaaagct cagggttatg aagtaggaac ttctttactt gaaatagata aagttgaata
     3241 tgctaaagaa atgatggaaa aagctaagaa taagggtgtt aacttattat taccagtaga
     3301 cgttgttatg gcagaccact ttgcaccaga tgctactcca atagtaacag aagatgctaa
     3361 tgtaaaagaa gattacatgg gactagatat gggacctaag actatagcaa actttgtaaa
     3421 aactataaaa gaatcaaaaa ctgtagtatg gaatgggcca atgggagtat ttgaatttga
     3481 aaactttgca aatggtacat tatcagtagc tagagctatg gcagagttga ctgatgcaac
     3541 tactgtaatt ggcggtggag atagtgcagc agcagttaat caattaggat ttggtgacaa
     3601 gatgactcac gtatcaacag gtggaggagc atcactagaa tttttagaag gtaaagaatt
     3661 accaggtatt gcagcattag ataataaata aactaatata tagaggagat tgtaaaatga
     3721 gaaaacctat aattgcagga aactggaaaa tgcataaaac aataaaagaa gctttagaat
     3781 ttgtaaatga agttaaagat aaagtaaatt ctgataaagt agaagctgtt atatgtgcac
     3841 catttacttt attaaaggat ttaaaagaag ctactaaggg tacaaatata aagataggtg
     3901 ctcaaaatat gcactttgaa gaaaaaggag catttacagg agaagtttca cctcttatgt
     3961 taaaagaaat agatatggac tatgttgtaa taggacattc agaaagaaga caatacttca
     4021 atgaaactga tgaaactgta aacaagaaag ttttaaaagc attagaagta ggaatagacc
     4081 caatattatg tgttggagaa actttagaac aaagagaagc tggaaaaact aaagatgttt
     4141 gtaaagttca agttgaaaaa gctttagaaa atgttcttaa agatgattta gcaaaagtag
     4201 ttgttgcata tgagccaatc tgggctattg gaactggtaa aactgcaact gctgaagatg
     4261 ctaatgacgt tatatcttat ataagagaag ttataaaagg attatatgga gaattagcta
     4321 atgaagttag aatacaatac ggtggaagtg ttaaaccttc aaatgtagcc gaaataatgg
     4381 gtcaaagtga tatagatgga gctttagtag gtggagctag tttagctagt aatgattacc
     4441 tagaccttgt taatttctaa ggagtgaaat gatgaaaaaa ccagttgctt taattattat
     4501 ggacgggttt ggatacaata aggatgttaa gggaaatgca attgctgagt ccaaaactcc
     4561 taatttagat agaataaaaa aagagtatcc aaacacattg ataaatgcta gtggtcttga
     4621 tgttggtcta cctgatggtc aaatgggaaa ttcagaagtt ggacacacta acataggtgc
     4681 aggtagaata gtatatcaag atttaactag aataacaaaa tctataaaag atggtgactt
     4741 ttttactaat aaagttttat gtgaagcaat ggataatgca aaagaaaact ctcttcatgt
     4801 aatgggactt ttgtctgatg gaggagtaca ttcacatata gaccatctta aggctataat
     4861 caaaatggca aaagataaag gcgtacaaaa ggtgtatgtt cacgcattta ctgatggtag
     4921 agatactgac cctcaaagtg cattagaata tgccaaagaa gtacaagcta gtatggatga
     4981 aattggagta ggtgaatttg ctacagtttc tggtagatac tacgctatgg atagagataa
     5041 gagatgggaa agagtagaac ttgcatacaa tgccatggtt agaggtattg gtgaaaaagc
     5101 aaattctatt gaggaagcta ttcaaaactc ttatgatgat ggaaaaaatg atgagtttat
     5161 aatgccaaca gttattatga aagatgataa accagttgga agtataaagg aaaatgattc
     5221 aattatattc ttcaacttta gaccagatag agctagacaa ataactagag ctttagtttg
     5281 tgaagagttt gatggattta aaagagaaga tattaaaaac ttctttgtat gcttaacaga
     5341 gtacgatata actatagaga atgtgcatat agcatttgga cctcaatctt tagccaacac
     5401 tctaggtgag tatctagcta aaaatggaaa aactcaactt agagctgctg aaactgaaaa
     5461 gtatgcacat gtaactttct tcttcaatgg tggagtagaa gagccaaata aaggtgaaga
     5521 aagactattg ataccttctc caaaggttgc aacttatgat ttaaaaccag aaatgtcagc
     5581 atatgaattg acagataaag ctttagataa attaggagaa gataagtttg actttatagt
     5641 attaaacttt gcaaatcctg atatggtagg tcacacagga agtatagaag cggctataaa
     5701 ggctgttgaa actgtagata cttgtgtagg aagattgata gataaaatag tagagttagg
     5761 tggaagtgca ataataactg ctgaccacgg aaatgctgaa tatatgttag acccagaaac
     5821 aggaaaaact gtaacggctc actctattaa tccagtacca tttattgtag ttggtcaaga
     5881 atatgaaagt gcaaaattat tggatggagg aagattatct gatatagcac ctactatttt
     5941 agatatgatg aagttagaaa agccagaaga aatgactggt cattcactta tttcaaaata
     6001 gtcgattctg ataagtagat aataatatat aaactacaat ataaatttaa aaataatgca
     6061 gtttaggttt attttgtaaa gtttagactt tatgacataa ggtttaaatt ttgtaagttc
     6121 tggatattgt aaggtgtaga tgaagatata ttttataaaa tttacaagat agacaa
//
LOCUS       DAEHWO010000139         6165 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEHWO010000139 DAEHWO010000000
VERSION     DAEHWO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6165
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.142"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            76..726
                     /locus_tag="KNP54_003802"
     CDS             76..726
                     /locus_tag="KNP54_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBF0894654.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(866..2242)
                     /locus_tag="KNP54_003803"
     CDS             complement(866..2242)
                     /locus_tag="KNP54_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBF0894655.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2258..4171)
                     /locus_tag="KNP54_003804"
     CDS             complement(2258..4171)
                     /locus_tag="KNP54_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBF0894656.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4307..4939
                     /locus_tag="KNP54_003805"
     CDS             4307..4939
                     /locus_tag="KNP54_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBF0894657.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5078..5617
                     /locus_tag="KNP54_003806"
     CDS             5078..5617
                     /locus_tag="KNP54_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBF0894658.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(5793..5963)
                     /locus_tag="KNP54_003807"
     CDS             complement(5793..5963)
                     /locus_tag="KNP54_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBF0894659.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
BASE COUNT         2285 a          857 c          858 g         2165 t
ORIGIN      
        1 tttattaaaa ataatataaa ttaaaacata taaataaaat attttataca atatattgta
       61 aaggaggtaa ctttgatgaa agcagaaaaa acaagtatat atccaattat taaaaataat
      121 ttaaacaaaa tatcaattgt tgaatataaa aagggtcaaa gatttgtagc atcagataaa
      181 gacttacaag aagtgttctt tataatagag ggagttgcat tagtggagtg tactactaga
      241 ggaggaaata aatttcttgt tgacattgta cctgaaaatg aatttatagg caaaattagt
      301 tacatatatg aacataattt gaaatgtgat atatttgcaa agaccaatat aaaattattt
      361 cgatttgaaa aaaatgtatt tgaagagttt tatctcaaac cagattttat tgcactattt
      421 cacagaaaat gtacaagaag aatatatgaa ttatataaaa ccagaatggt aagagaacta
      481 ttttcttgca cagaagttat tgcctattgt atatcaaata aacaagaaaa taatgtctgc
      541 aatataaaag ctattcgtaa tttcagtgaa atctattcaa ttagtagaaa aagtagatac
      601 cattctctgc taaagttaac tgaaaaggag atagtaaaaa aaatgggtaa tacatatgaa
      661 attttaaact atgatgaatt acataaattg gcatttgaag taaaagaatt tttggaagat
      721 gagtaaaaat tgttacttaa tcaaaataaa gtataataat ttctgtaaaa aatagaaata
      781 gtctcactga aaatcaaaaa tactttagtt attttcaatg agactgttta gaaatattgt
      841 atacttataa tgtatagtat aattattaat caatttcctt tactatatta atagcccatt
      901 ttttagataa tgctctagga acaccaaata taaacttaac cacttcttca ctataagtga
      961 gcaaaacgag tacaaatata ggtgcacctt taaatgcagc tataaaagtt agaggaatag
     1021 aagctaacca catacatcct aattctaaaa atagagcata tttagtatct cctccacttc
     1081 ttaaaatacc aattataacc aatgtattaa aagatttaag agccattagt attcccatta
     1141 taaagaatat cttagttata tcagaagcta agctatcaga aacactaaac atttttaata
     1201 ataatggtat atttaaaatt aaaataattc caagtattaa accagctgaa aatacaagta
     1261 tagaaaactt tttagcatat tcaatggctc ttttaatatg gtcagctcca agttcatttc
     1321 caagcataat agatgcacca gatgcaatac atacagctgt cattatgaag aaattacctg
     1381 tactggttgc tatctggcta gctgctatag cagaagtacc agctcttgca tatgcaacag
     1441 aatacaggac agttccaatt gcccatacag agtcatttac aaatatagga aagctttttg
     1501 atgaaaaaga ttttataaaa attttatcaa tagcttttag attttttaga ccaaacttta
     1561 atatatagtc ttttttataa aggtaaacat aagtaatcat taaaattaat tcacatattc
     1621 tagcaataac agtagctaga gcagcacctt ttacacccaa tgcaggaaga ccgaagttac
     1681 caaatataaa tccataattt aaaataacat ttgttacaag tgcaaatgca ctacaaatca
     1741 tacctaactt aggatttcta acacctcttg aaccagtgct aaatacagta cttacagcaa
     1801 ttaatggata actaaatact gcaatactaa agtaatctat acaaagtttt accacctcag
     1861 aatcatacga aaatatgtgt ataattggct ttggtgttag taaagcagga ataacaaata
     1921 caaaacttaa aacaattgcc aatacacaag taagacctgt gacttttctt atattactca
     1981 catccttctt tccataaaac tgtgaaataa aaactccagc acctcctgtg ataccagata
     2041 aggacatatt aaaaagaaag aaaaattggt ttgcaactcc aactgaagct acagatgttt
     2101 cccccaaact acttatcata attgtatcta ttacatttac agaagtagaa attaagttct
     2161 gtatgataat aggtatacat aaagatagaa gtattttata aaatctttta ttttcgtctt
     2221 ttaaagaaaa tagttcttgc aaataatcct ctccttttta cataaattct tcccactcat
     2281 catatagaga ggcaaggtta ttttctaaat taattttttc ttggctaact tctttagctt
     2341 tatctggatt agagtatact tcttcttgac ataaaagtat atctaatttt tcaatttcaa
     2401 tctctaactt ttcaatttct ttttctatat tttgtctttt tattctattt ttcttttcta
     2461 tttctctttg ttctctctct tttctttttt catcttttat ttgagttcta gttttttctt
     2521 ctttttcttc tataatactc atctcttgga tttgcctttt tttatctata taataatcat
     2581 aatttcccag atattcagta attccatttt catctaaaac taaaatttta tcaacaacag
     2641 tatttagaaa gtatctatca tgtgatattg taaatatagt cccatcataa ttagttaatg
     2701 cctcttcaag gacttcctta gaatcaatat ctaggtgatt agtaggctca tctaataaca
     2761 ataagtttgc atttgatagt ataagtttaa gtatggcaac tctagctctt tctccaccac
     2821 tcaatgtaga aatcttctta aaaacttctt catctacaaa taaaaatgcc cctaacatat
     2881 ttctcaaagt agtttgagta agatgagtat tattttccca aatctcatca attattgtgt
     2941 tatctaaatt aagagttttt tgttcctgat ggaagtagga aacatgtaca ttagttccaa
     3001 atttaatatt gccactaaga ggttgtagtt cattagttat tattttaaat aatgtagatt
     3061 tgccaacacc atttgcacct ataagtgcaa ctttttcccc tctatatata tctaaatcca
     3121 agtctttaaa aagtattctt tctccataac ccatagatac atctctaatt tgaagaacat
     3181 cattaccact ctggacagaa ggcgtaaatt gtatacgagc ttttttccta taagcttctg
     3241 gtttatctaa aacgtctacc ttgtctaatg ctttttcttt acttcttgca cgctttaggt
     3301 gtttttctct accataagct tttagtcttt caattgattc ttcttgcttt tttatttctt
     3361 tttgttggtc ttcaaatttc ttaagctcta gttctttttc tattttagat aactcaacaa
     3421 atttagagta gttaccatta tatactttaa gttttttgtt gtgaacttca aaaattctat
     3481 ttacggattg gtctaagaaa tatctatcat gagatattaa catgacagtc cctttatatt
     3541 gttttaaaaa tacttctaac cattctattg cttcagagtc taagtggtta gtaggttcat
     3601 caagtaacaa tagagttggt ttcttaagaa gtaattttcc taaaagaact ctagtttttt
     3661 caccaccaga aagtatgctt attggcttat ccatatcatt gtcactaaat cctaatccct
     3721 ttagaactcc tttggcttca gatttatatc catatccatt taaatctgaa aataattcta
     3781 gtttatgtga atattcatcc atgatttttt ctataattgg agagtttgtt tttgtacttt
     3841 cttcagatat tttaacctcc aattctctta aataggattc catttctatc aaatttttaa
     3901 aaacttctag tacttcttcc aaaatagtat tatccgaata aaaattggta ttttgttcta
     3961 aatatccgat ttcacaatct ttagaagtgt aaatatctcc actatcatat ccataaattc
     4021 ctgaaattat tttaaataaa gtagtttttc cagtaccatt aacaccgatt ataccaattt
     4081 tatcgccttc atttactgta aaactaatat tttctaatat agaatctata ccaaaacttt
     4141 tatttaagtt attacatgac aaaacaatca taaatttcta cctccttgaa ctatctaaaa
     4201 ttataatgtt ttgatataat ataatcaagg ttatatgtat tagttttgaa aaagaaatat
     4261 tttattgtga atcaaacaaa aaagaggaca cttttaggag gtgaagatgt tgggaaataa
     4321 aaatatatca atggcagtta taagaaggct cccaaaatat catagatatc ttggagactt
     4381 attagatagg gatatacaaa gaatatcttc taaagaattg agtgatataa tagggtttac
     4441 cgcttctcaa ataagacaag atttaaacaa ctttggtgga tttggacaac aaggatatgg
     4501 ttataatgta gaagctcttc atactgagat aggtaaaatt cttgggttgg atcgaccata
     4561 caacgcagtt cttgtaggag caggtaactt aggacaagct atagccaatt atgcaggatt
     4621 tagaaaagct ggattcgaga taaaagcttt atttgatgca aatcctagaa tgataggttt
     4681 aaagataaga gagtttgaag tattagattc agatacttta gaagacttta taaaaaacaa
     4741 taatatagat attgctgtat tatgtatacc taaaaatgga gcacaagaag ttattaatag
     4801 agttgtaaaa gctggaatca aaggtgtatg gaattttgca cctttagatt tagaagttcc
     4861 gaaaggtgtt atagttgaaa atgtaaactt aacagaaagt ttatttacct tatcgtattt
     4921 aatgaaagaa ggaaagtaga caacttaaac atattaataa tgagcagttg tgaagagtat
     4981 tgagaaagtc agaagattta atattaaatc ctctggcttt ttgaaatatt aggataaaaa
     5041 tttaaataat gtatggaaat aaacaatatt aaggagagtg gtttttgtgg aggaattatg
     5101 gaaaaaggca attgaatttc atggtcatga atgtccaggg ttagctatag gatttaaagc
     5161 agcacttgca gcaagagaat atttaggatg taaacagtca ggagatgagg aaattgtatg
     5221 tatttctgaa aatgatgctt gtggaataga tggtatacaa gtcgtgctaa gttgcacaat
     5281 gggtaaagga aatttactac ttaggatgac tgggaaatca gtatatcatt tctttaatag
     5341 ggaaaatgga aaatctataa gaatatatgt aaagtcaaag ccatttcaaa tggatagaga
     5401 aggatacaaa aagtacttat tagaaagtga ttttgaagaa atatttgaga ttacagatac
     5461 taagttaaga cttcctgaaa aagcaagaat atttaaatct cttaaatgtg aagtgtgtgg
     5521 tgaatttgca tctgagcaat atataaggat tgaagaagga aagaaagtat gtcttgattg
     5581 ctttaataaa tatgaaagat tttatgagga gtattaaaat tataaattag attaaagtta
     5641 aaagtattag atatgtgcta acagtatttt aagatgaatt aggtagcaac ataataaagt
     5701 atataaataa tattaattga atcatacata attaaaaaga ggctgattag tatttataaa
     5761 ataaaatcag tctctttatg aataacgaat tattattctg gttgaggtgc atctacagga
     5821 caagctcctg cacaagaacc acagtctata caagaaccag catctataac atatgcgtcg
     5881 tctccagctg atatacagct aacagggcat tcagcctcac aagcaccaca gcttatacaa
     5941 gcgtcagtaa ttttatatgc cattttgaaa tcctcccttt tatatgtatt gtaattcaat
     6001 aacattataa caaatattat tgaatataac aattaaatta attctacaac aaaaacttta
     6061 ttatgatatt cttgttttaa agttttacaa taaagtttaa tctgcttata tttttattta
     6121 ttttaaagaa gtttatttta aaaataaaat taaatttaaa aagtt
//
LOCUS       DAEHWO010000140         5665 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEHWO010000140 DAEHWO010000000
VERSION     DAEHWO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5665
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.143"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            897..1202
                     /locus_tag="KNP54_003808"
     CDS             897..1202
                     /locus_tag="KNP54_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894660.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            1610..2299
                     /locus_tag="KNP54_003809"
     CDS             1610..2299
                     /locus_tag="KNP54_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894661.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            2299..3216
                     /locus_tag="KNP54_003810"
     CDS             2299..3216
                     /locus_tag="KNP54_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBF0894662.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAMLQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLVNSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            3289..4215
                     /locus_tag="KNP54_003811"
     CDS             3289..4215
                     /locus_tag="KNP54_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894663.1"
                     /translation="MNYIIETNQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            4212..4892
                     /locus_tag="KNP54_003812"
     CDS             4212..4892
                     /locus_tag="KNP54_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894664.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4990..5325
                     /locus_tag="KNP54_003813"
                     /pseudo
     CDS             4990..5325
                     /locus_tag="KNP54_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
BASE COUNT         2253 a          573 c          882 g         1957 t
ORIGIN      
        1 aaaaccaagc taatagatta gagaataaat gactcataga tgaaaaacca agctaatgga
       61 ttaaagaatg aatgatttat agatgaaaaa gaaagcttat agattagaga ataaatgatt
      121 tataggtaaa aaccaagcta atagattaaa aaatgaatga tttatagatt aagaagtaag
      181 cttatagatt agagaataaa tgacttataa ataaaaacca agctaataga ttagagaatg
      241 aattaattat aggtaaaaac caagctaata gattagagaa taaatgactt ataaataaaa
      301 accaagctaa tagattagag aatgaattaa ttatagataa aaatcaagct catagattaa
      361 aaaataaatg atttatagat gaagaactaa acttatagat taaaaaataa atgacttatt
      421 tatagatgaa aaaccaaact tatagattaa aaaataaatg atttatagat gaagaactaa
      481 acttatagat taaaaaatga cttatttata gatgaaaaac caaactcata gattaaaaaa
      541 taaatgactt atagatgaaa aatcaagctc atagattaaa gaataaataa cttattagat
      601 gaaaaaccaa gcttatagat aagaagtcca tgcttataag ccagaaaatg aatactttaa
      661 tagattaaaa aatacatatt tgtgaattat agaatgaatg actccataaa ctagaaaatt
      721 tataataata tctatataaa aattagaagt attttatcac aaaaaaatta agttaaataa
      781 atatgaaatt acttccaaat atacttccaa aaacatgtaa tcgcatatat aatataatta
      841 taaaaataat aaatattttt atagtagtag ttaattatta ataaggaggg gtcaaaatgc
      901 ctagcatgat tatggaagtt gtaggagtac tatttatagc tattggatta atcttgacat
      961 tcattgaaat aaaaggaaat ttcccttctt tttatggttt tggtcaaaat tctataggga
     1021 aaaatgctgt aggtattata gcagcaggaa ttgctttaat tttctttaga aatggcatag
     1081 atagcataga ttctatagct acttatggtg tatttttagc aatagaactt gttgtaatag
     1141 ttgcatattt cttaataaga aaaaaattta ctaaagaaga taaacattta agaactaatt
     1201 aactaaatta tctactataa aattggaaaa ttaaaaacaa ataaaagttt gtttttaatt
     1261 atttaaaatc caaatttgat tatttttaaa gaaactatgt tctgtataaa actagaatgt
     1321 ggtttctttt ttatgtataa aatatttttt agcaagagtt aaaaggtgtt ttataatata
     1381 aaatagttaa ttgtagatgt taataaaaga aaattatgta tatttcagat aaagataaga
     1441 gagtatacta tattttaatt attttttcaa taaagcttat tgaaaagaac tttaacttag
     1501 aagagtatca ccaaattgca gatacaatat cataagcagt tatttattga caaccctttt
     1561 taataaatat atcatttgaa gtatactgac gaaaaggagt tgaataataa tggacatctt
     1621 attggttgaa gatgataaga atattcgaga aatggtatac gattttctga ttagtgagaa
     1681 ttactctgtt aaaactgcca ttgatggaaa tacagctatt gaaatattta aaaattattc
     1741 atttgatatt attttactgg acttgatgtt accaaagtct agtggttttg aagtattaaa
     1801 atatatacga agtgtgagtg ttgttcctgt tattattact actgcgaaag atagtgacac
     1861 agataaaatg ctagggctta atcttggtgc agatgattat attacaaagc ctttttcaat
     1921 cgtagaattg cttgcaagaa ttaaagctaa tattagacgt gcaacagtgt acagcagttc
     1981 aagaaactct gaagatatgg ttattcagta taaagatttg attataaata tatcaaaata
     2041 tgtagtttca aagaatggaa ttgacttaaa cttaacacat acagaatttg aaattgttaa
     2101 attactagcg actaatcaag gacgtgcttt ttcaaaggaa caattataca acgctatttg
     2161 gaaagaacct tattatggaa atgaaaatgt gctaaatact catattaaca ggttaagaaa
     2221 taaattgtct gatggtatag aaaaaaataa ttatattaaa actctttggg gaattggcta
     2281 caaaatggag gaagaataat ggagttattt ttagttgtaa tttcgattgt actatttgct
     2341 ctctacttaa aagaacgaaa taaatcaaag aaaatggaaa gtgattataa gtatatcaat
     2401 tcaagacttc gtgacataac aaatgatgat gaaattaatt atattttagt accatctgat
     2461 atttcgattg taaaagaaac agcagtagat ataaataaac ttcttgaaaa gttttacagc
     2521 aggcaaatta attataatag aagtgaaaaa gcgatgttgc aaatatttac aaacatatca
     2581 cacgatttac gaactcccat cacagtatta aagggttata ttgaaatgtt atatcttcaa
     2641 agtcaaaaag aagaattatc ttcttcaatg agagcaactg tggaaaaaat gcaaacaaat
     2701 tcaaatgagc ttgttaattc aataaataac ctgtttaata tggcaaaaat ccaatctgga
     2761 gatatgatat taaatcttca aaaatccaat ctaacacaat tatgtcatga gattatttta
     2821 gagttttatg atttgctaga taaagaaaac tttaatgttg aagttaatat tgaagataga
     2881 cctatatatg caaatgttga cacagaagca ttacaacgta tactcaaaaa tttaattgat
     2941 aatgctataa aatatggttc agatggtaga tttttaggga tttcactata tgaaaaggaa
     3001 aaacatgttt ttatagatat tgaggataaa ggttcaggta tttctgaaac tgaaaaagag
     3061 catattttca caagagctta tactgctgac agaaaaaaag gcaatggttt aggtttggct
     3121 atttctcaag ggcttgtaaa ctctatggga ggttcaattt atgtaaatag tagacctaat
     3181 gtaaaaacag tttttacagt aaaattgaaa agttagaaaa aagttagatt taaaagagag
     3241 aaaagataat tttattttgt atactgtttt tagaaaggag ggagtatgat gaactatatc
     3301 atagagacca atcaattaaa gaaaatatat aaagataaag ctgttgttaa tgctgttaat
     3361 attcatgtga aaaagggaga aatttatgga tttgttggac caaacggggc aggtaaaagt
     3421 acagtaatga aaatgttgct aaatcttgtt aagccaaatt ctggagaaat agttatgttc
     3481 ggtaagaaag tggcagaaac tgattttgaa atattaaaaa agattggtac tattattgaa
     3541 aatccgtatt tatatgagaa tttgactgct aaacagaatc ttgatttaca ctgtgaatat
     3601 atgggttatt ataacaaaga acatatatca gaggtattgg aatgtgtcgg attgtcaaag
     3661 caatcaaaca agaaagtttc aaaatattct ttagggatga aacaacgtct tgcaatagct
     3721 agagcaattc ttactaaacc agaattattg attcttgatg aacctataaa tgcactcgac
     3781 ccagagggga taagagaaat gcgagaatta ttccgtaagt taaatacaga ttatggaata
     3841 actatattta tttctagtca tattctttca gaggtagaac aaattgcgga cactattgga
     3901 attattcaag atggtaaact tattaaagaa atttctatgt cagatataca caaatatcaa
     3961 acagattatg ttgaagtaga tgtagataat gtggagcttg ctggatactt gttagaaaaa
     4021 gaatttggaa taaaagactt taaaattact tcggaaagtt gtattgaaat atatgattta
     4081 cgaaaagatg taaaagaaat atccaaaata tttattcaaa atcaaattgg tataaatagc
     4141 attggacgta aacaaagttc tttagaagat tacttcttcc aaactacagg tacaggaggt
     4201 aaagaaacac tatgatacat ttaatgaaac tagagctaaa aaaagttggg ctaaaaagat
     4261 attttttatt ttcaatgctg gggattttct tatgtatgtt ttttgtcttt actggattga
     4321 atgataaatc tacttcaata tatgattatg atgttacatt taggacaatc agtttatttt
     4381 tctgttttta ctatattata ttatttgctg tgttgaatgt ggcatatata ataaatgaat
     4441 atacaaataa aacaatcttg attttattct cttatccact tgaccgtaaa aaacttattt
     4501 tatcaaagtt acttttgatt acgactctta tgatatcatc aatgatagtt ggatatatct
     4561 gttgttttac attcgttgtt gtgttggata agtattttaa tttagttatt ggagattttc
     4621 atatttcaat tttatcttat tggataccag gagcaattaa aagtattatt gtattttgct
     4681 cattaggtat atggacattc gttgttggaa tgataagaaa atcaatacct gttacccttg
     4741 tcagttcaat tatttttatc aatttaagac aatttatttt agctggtaca aatacaactc
     4801 aagacagttt gatttctgtt tttattatag ttggtataac tgtgattggt atatattata
     4861 tactaaatca taaagttact gaaattgact agatactgtg gataggaagg tagttattaa
     4921 ttgtatcttc tcgggataat aatgatttgc tattatatca gctattatta atattattag
     4981 agttttaata atattgcaca accatttgaa gttgagccaa agcttgatga attaattgaa
     5041 tggtactata gtcagagtga agtatctatt aaagttataa ctgaatttca ttatagattt
     5101 gaattgatac atccatttca agatggtaat ggtcacatag gtagatttgt tatgctaaaa
     5161 cagatgttag aaaataatct tcctataaaa attgtatctt gggatagtga ggaattgtat
     5221 agaaactcct taaattcttg tagtttaggt aattatgtcc ctttaattga atatttatca
     5281 agtttagaag attttagaga agtatataaa atgttatgga aataattgtt tgcagcaaaa
     5341 aaagtttata tataaatgta tttttatcta tgctatttaa cgctaatttc ttagttattc
     5401 ttagcttgga ctatacccac tattttaact atataaaata gtggatatag tttaactatc
     5461 tctttataac tatttttatg tatcttagtt gtttcttaat atggggacag ttcataaaac
     5521 taaaagtgat ttttaatttt atcatttata atttaccatt acatcagaaa aatgcttatc
     5581 attagaattt tcataaaagg tacctatttt tttcaattaa ctgaatcaat tctattagtc
     5641 ttaatctttc atatttcaaa ttgat
//
LOCUS       DAEHWO010000141         5631 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEHWO010000141 DAEHWO010000000
VERSION     DAEHWO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5631
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.144"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            235..741
                     /locus_tag="KNP54_003814"
     CDS             235..741
                     /locus_tag="KNP54_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBF0894665.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            1154..1822
                     /locus_tag="KNP54_003815"
     CDS             1154..1822
                     /locus_tag="KNP54_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894666.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            1981..2487
                     /locus_tag="KNP54_003816"
     CDS             1981..2487
                     /locus_tag="KNP54_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBF0894667.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            2615..3631
                     /locus_tag="KNP54_003817"
     CDS             2615..3631
                     /locus_tag="KNP54_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBF0894668.1"
                     /translation="MGYYNDNDNNKIRRKKISNSKDSNKKSKHSYTPANKKNKSSKTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            3985..4689
                     /locus_tag="KNP54_003818"
     CDS             3985..4689
                     /locus_tag="KNP54_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBF0894669.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            4984..5463
                     /locus_tag="KNP54_003819"
     CDS             4984..5463
                     /locus_tag="KNP54_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBF0894670.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         2349 a          475 c          929 g         1878 t
ORIGIN      
        1 ttgtatattg ctttaggttt aaaaatatat tatatacttt ataatcaata tattttatct
       61 atattttaca cttataaaat atgaaaacta cttattgcga aagtaattga tttgttgtat
      121 tataatttac atgaattatg taggacaatc aaaagtcagt attataagag tacatatatt
      181 caaattttta acaattaatt tatataatta aaaaatgaag ggtaggatga agtcatgggt
      241 tttagagaag taaaaattga ggaattacag tttaatccat ttactaagat tggcaaagaa
      301 tggttactta taacagctgg tgattcagaa aagtttaaca caatgactgc tagctggggt
      361 ggtgttggag tctattgggg taaaaatgtt gttacaactt acataagacc acagagatat
      421 acaaaagaat ttgtagatag taatgataca tttacagttg ccttctttga tgaaacgtat
      481 agagaggctt taaatatttg tggtactatt tctggtagag atataaataa aatagaaaaa
      541 gcaggactta caccatattt tgtggatgat acagtagctt ttgaagaagc taatatgatt
      601 atagtatgta aaaagctata tcatggtaat atgccaccag aaaactttga tgctaaagaa
      661 aatgataaaa aatggtatcc agagaaagac taccatacta tgtacatttc agaaattata
      721 aaagttcttg taaaagaata attataataa aaaatatatg aaaagaactt attataagta
      781 aatgactgtg ctttcttatc tgatatctaa gtagatgcta gtaactaaat aaatattaat
      841 tttaaataaa tactattata aaaaagatga actatattta ctatagttca tctttttatt
      901 tatataagca cttatataag tagagattta tttgaataaa agtatttatt tgaaatattt
      961 gagtatactt tataagtatt tttatgctaa ctagaaacac ttaatttatg gcatttgtat
     1021 ttgatttatt ttaatgtaaa taatttcaaa gttaatttta ttcaatatag tactataaaa
     1081 gtataaataa catttaataa aaatatatat tatattaggt attttaaata aattttttaa
     1141 agggtgattt tttatggaaa atataactag ttattttaca acaatactat gtgtatttat
     1201 atgcttatca tctgtattta tatttactca actagctaga gtatttatta ataagaagaa
     1261 gattaatcaa aaaattaaat caagaaacgg atttaggtat gatagagatt ttattgaagc
     1321 cagaagagaa gaaatacata taaaggataa caataataat aaaaataaga gtaacaataa
     1381 gaaattaaag ggagaaaaag tatttaaata cgataatggt gatttatata aaggtgagtt
     1441 tgttgatgga aagaaaaatg gatttgggat atatattttt tcaagtaagg aaaagtatga
     1501 aggattatgg aaagatgaca agatgcatgg aataggaaaa tatacttata gagatggttc
     1561 aatatataca ggtgaattta aatacggatt aaaaaatggt ttgggaaaat taacatatcc
     1621 caataatgac atttataagg gatatttttt agataataag aaaaatggta agggtgtatt
     1681 atataaaaat gatggaaata aacaagcagg aatatgggaa gatgatgaac aatgtaaaag
     1741 tttagatttt aaagatttaa ataataataa aataaataat gtttatcaaa atagattaaa
     1801 taacaataaa ttaaaagttt aattattcta ataaaaaaat ctttatttat gatggaatat
     1861 aggatatatc tatgttgtaa tttgtaaaat cttcctatat catataaaat taagtattga
     1921 ttagtctatt acataaatat agaatataaa tatatccatt taataataag gagaagagat
     1981 atgaaagagt atgtagttgt ggatttagaa actacaggat tagatccata taaaggttgt
     2041 gaaataatag aaataggaat aacagaaata aaaaatgaac aaattgtaaa aaactattca
     2101 aggttgataa aacctaaggg gataatttct tcatttataa cagaattgac acatataagt
     2161 aatgaaatgg tagaaaatga agaaccacta gaattagttt tacctagatt tagaaaatac
     2221 ataggtgata gaactataat tgcacacaat gcgaaatttg atttaaaatt tttaaattac
     2281 tatcttagaa tgttagattt agaaccaata aacaattata tatgtacagt agagttatta
     2341 aaaaaatgta aaagttataa aggaaaaaac aagaaacttg aaacagcttg tgcttattac
     2401 aacatagaga atataaatgc tcatagagct gacagtgata cattagcaac tgcaaaacta
     2461 tttttgaaaa taaaagatga atattaatta taaatataga gaaaattagt gaaaatatcc
     2521 tttataaaat tgacccttaa gcttacaatt ttgttctttg atttattttg tagaacaatg
     2581 tataatgtac cttatatgaa gaagggagac taaaatgggt tattacaatg ataatgataa
     2641 taataaaata agacgtaaaa aaattagtaa cagcaaagat agtaataaaa aatctaaaca
     2701 ttcttatact ccggcaaata aaaaaaataa aagttctaag acaagttcta gtaaaagaat
     2761 gagtgaaaaa gtagattcac agaatcttat aaaaagagat agagatagtt ttacaagaga
     2821 taatgtaaga cctttaaata cagattacaa tcaaagagaa agaagaagag tcgagtataa
     2881 acaaagagag aaaaaattaa aaagtaaaaa aagaaaaaaa caaaaaagga ttagaatagt
     2941 tagagcatta ttatctatta tgttagttgc actaattata ttttcagtgg caggtgcaat
     3001 atttacagtt tcagctataa aagggtcacc agaagttact aaaaagttaa ttaggtctaa
     3061 atatataagt agtgaggttg taagtataaa acaaatgcca aatgatttaa aacatgcaat
     3121 agtttccata gaagatgaga gattttataa gcataaagga gtagatgtta tttctctagt
     3181 taggtcagta ttaaacaatg tgtttacaga tacaacacaa ggtgcaagta ctatagatat
     3241 gcaagtttca aaaaacctgc ttactagtaa tgataaaact atgaagcgga aaataaggga
     3301 tatgtataat gctaagcaga tgaataagat tatgactaag gatgaaattc ttgaagcata
     3361 tttaaataat atgtatctag gtaaaaatgc atatggagct gcaaagggag ctgaagtcta
     3421 ctttggtaaa aaagttagtg aattaaattt agctgagtgt gctatgttag ctggtatgac
     3481 aaataatcct gcaaggtata ttgaccatgg agaggctaag aagagacaag tgattgtact
     3541 gtataagatg catcagcttg gttatataac tgataaggag tatagaatag caaaagctga
     3601 tgacactcca tttaaatcag aaattgatta aaattgtaag aatatagtat tttcaatagt
     3661 ttaaacaaac aaaaatgtaa taaaaaaggt gatttgccac ccatttgcca ccataattat
     3721 aatctaatgg caaattgttt taatgtacaa actagataat agaatattgt cttaaatgct
     3781 atattatgct aaaatttaat tgtattttgt aaattaaaaa acttataatt tagttttcta
     3841 gggttccgca ttttataatg gtcaggtcca agagaaaacg cgcaattgtt gtgtacacgg
     3901 aaggataaaa gcctgggaga tatttaagaa tatttctata ggctttttta tttttacata
     3961 ttttaaattt gaggaggttt tctaatgaaa aaatttgtta ttgaggatgc attttggaat
     4021 ctatttccta gtgcaaaaat tggagttgtt atttgtaatg atatagataa ctctataaaa
     4081 gatgaagact ataagaaaat aattttgaag ggagaagaag aagcattaaa atacttggag
     4141 gactcagaat ttagcaacaa ccaagtgatt aaagtatgga gagaagcatt taaaaaattt
     4201 aaaacgaaaa aaggagcaag gtcttctatt gaagcattat taaaaagagt tcataatgga
     4261 aataatatag gaactattaa ccctttagtg gatatctaca attttatctc attaaaatat
     4321 gcattacctt gtggagggga ggatatagat aaatttatag gagatattag gctaactaga
     4381 gcaattggta atgaggagtt tatcccacta gggacagatg aaaattcatt tccatatgaa
     4441 ggagaaataa tttataaaga tgatggtgga gcaatttgta gatgttggaa ttggcgtgaa
     4501 gcagtgagaa caatgcttac tgaagatact aacaatgcct ttttatgcat tgaattagta
     4561 gatgaaagta gatttaaaga atttgaaaat gctttaaatg aattagctaa aatagttcaa
     4621 gaaaaattgg gtgggaattg taaaatttca attttagata ttgataataa agaggtatca
     4681 gtggattaat atggaggtgc tgttgtaatg gactattcta gttataaaga tacttatatt
     4741 tagggtaaga aggtctattt tagatataac gattatcaaa ggatataata tagaaaataa
     4801 aaatgtagaa tataaaaagc ctttaaaata agaaaaaaat gtattttaaa ggcttttatt
     4861 atactctttt ttatttgcat aattaacaat aaaaatatat tgttaattat aatattttta
     4921 ttgaaaaacg atataatata atgtattata ctatatataa aatattttaa aggagttggc
     4981 atgatgtcta ataaacttat aaaaaattta ctaagtggta tattacaaat tttatttttt
     5041 cttttaggat tagtaattgt tgcaggagga tttaaaagtt ttatgtacct ctgttttagt
     5101 ggagaagcaa ctctacaagg tactatttat ggaatattaa tgtttatttt aggtgtatca
     5161 tattttatca ttataaaatc attgatagaa gtattaggta gttctgaata tagcctattt
     5221 gtaaaagaga atgtaaaaag atttaggatt attggatatc ttttgctttt aaactctcta
     5281 attgagttta tttcaacttt tggtactact ggaaaaggaa tgagatttct agatttagga
     5341 tttggatttt attttactgt tccagtattt gtatatttta taacttctct tatgagtttt
     5401 gtaattgcag atggatttgt aaaggcaata aagataaaag aggataatga tttaactatt
     5461 tagatgtgac actttaatat ataggagata aataacccga aaagagtgac taactagtaa
     5521 tttaaaataa aatatattag ggtataatac ataaactata atgctaaaat taaaagatta
     5581 taatactaaa atataattat gttttaatta aaataaagaa ctttattagt a
//
LOCUS       DAEHWO010000142         5525 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEHWO010000142 DAEHWO010000000
VERSION     DAEHWO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.145"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            47..163
                     /gene="rrf"
                     /locus_tag="KNP54_003820"
     rRNA            47..163
                     /gene="rrf"
                     /locus_tag="KNP54_003820"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(377..1561)
                     /locus_tag="KNP54_003821"
     CDS             complement(377..1561)
                     /locus_tag="KNP54_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBF0894671.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMVKLVNAVPVFIDTKKENGFKLTKDELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1934..4285
                     /locus_tag="KNP54_003822"
     CDS             1934..4285
                     /locus_tag="KNP54_003822"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBF0894672.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4307..4846
                     /gene="nrdG"
                     /locus_tag="KNP54_003823"
     CDS             4307..4846
                     /gene="nrdG"
                     /locus_tag="KNP54_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBF0894673.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2155 a          626 c          889 g         1855 t
ORIGIN      
        1 tataaactta ttaaaaactt aatagaaata ttaagcataa agattatgtg gttacaatag
       61 cagagaggat acacctgttc ccattccgaa cacagaagtt aagctctcta gcgctgatgg
      121 tacttggtgg gaaactgcct gggagagtag gacgtagcca cgtaattttt ttgttataat
      181 aaatttagaa tttaacttat atagtttaat ttgataattt gatgaaaaaa ataaaagact
      241 tactgatttt taaatctata ggtcttttat tttttatcta acatttaaat taagttgttg
      301 aatatatctt atattactta ccttatatat taattaccat taatacatta tatctaatta
      361 ctattcatct aaattattat gccattattt tatatacaaa ttcttttaat ttatctaatc
      421 cagataagaa agtattttca ctgcaagcat aggatatacg aatatattta tccataccaa
      481 atgctatgcc aggaacaact gcaacattat attcttctaa aaattgatta caaaattcta
      541 tagaaaaact atctttatat tcaaatttct cagatacttt agaaagatct ataaatatat
      601 agaatgcgcc atttggattc acatatccta cattatcaat agagtctagt tttgatttaa
      661 ttaaatctct tcttgattta tatgttttaa ccatattgtc tatgtcaatt gagcaatctt
      721 tcaaggctcc ataggctatg tattgtgctg ttagacttgg gtgagatata agatgtcctt
      781 gtatagaact cattgcttta gcaatcgttt tattagatgc agtatatcct aatcttaatc
      841 cagtcattgc agctgactta gaaaaaccat ttatagttat tgttatatct ttagcttctt
      901 cgcttaatga tgcaattgat gtaaattcac cagtgtagca tattttttca tatatttcat
      961 ctgctaaaat atatatttta ttttgtatgc atacatctac tatttctatt aattcatctt
     1021 ttgtataaac actaccagta ggatttgaag gattgtttat tacaagaatt tttgttttat
     1081 ctgttataga tttttcaagt tcatcttttg ttaacttaaa tccattttct tttttagtat
     1141 caataaaaac tggaacagca ttaactaact taaccatttc aggataacta acccaataag
     1201 gctttggtaa taagacttca tctccttcgt ctgttaaagc tagtaaagta tttgttattg
     1261 agttttttgc tccacttgat acaactattt catctattga atagttacag ttattttctt
     1321 caataagttt tttacagatt tcctctctaa gtatttttaa tcctggaact aaatcatatt
     1381 tagtgtaatc tttatttaaa gaatcaatac cataagattt tgcgttatta ggtacattaa
     1441 aatcgggttc tcctatacta agatttatta ctttaactcc attactttcc atttctttaa
     1501 ctttagaact aatacctatt gtgtaggatg gtgttataaa gtttagtctt tttgataaca
     1561 taaaatgcct ccttttaaat tattatttat attatacgac aaatttaaag aatttacata
     1621 aggaaatttg tagatatata cattaatata tataatagcc tacacttttt gcctaaaatt
     1681 agtgtaaaaa aaagagaaaa aaattttaac tttcaaagtt gttagaaacg ctactgttca
     1741 aaatatccac atagtatttg caatgatttg cgcaagtttg actattatgt acaaatttgg
     1801 taatcttaat atagcaatta ttaagataat ccctttaact tagttgaagg ggattttttt
     1861 agacttaaca tactacatat agtggtatgg ggattaataa aatacaatat atagtaacag
     1921 gaggtttttt taattggttg aattcgtaaa aaaaagagat ggaagagtaa ttccatttaa
     1981 tgaagataga ataacaagag ctatattttt agcagcaacg aatgttgcag aaagagaagg
     2041 aatagtacct gattataaat tatctgagca attaactcaa gaagtaataa agtttttaaa
     2101 tcataaatac tcagaatcag ttccaagtgt tgaagatata caagattctg tagttaaggt
     2161 tcttatagaa actggccatg caaaaactag tgaagaatat ataatataca gaactgaaag
     2221 aagtagaata agaaattcaa aaacaagatt gatgaaggca atagaggaaa ttacctttga
     2281 agatgcagaa gatgctgata taaaaagaga aaatgcaaat attaatggta atacagcaat
     2341 gggaactatg ttacaatatg gaagcactgt atctaaagaa ttttgtaaaa cacatatatt
     2401 aaaaccagag cattcttttg ctcatgataa tggagatata cacatacatg atatggattt
     2461 tttaaatatg ggaacattaa cttgttgtca aatagatgtt aaaaaactat tcaatggtgg
     2521 attttcaaca ggacatggct ttttaagaga gccacaagat ataataagtt atggtgcatt
     2581 agctgcaatt gctatacaaa gcaatcaaaa cgatcaacat ggaggtcaaa gtataccatt
     2641 tttcgattat ggattggctg aaggtgtata taagacattt aagaaattct acataggaaa
     2701 tttagctaaa gcattgaagt tatttaaagg aattgaaaat aatgatgtga taaagaacat
     2761 agtatataat acagagaaag aaacaaatca aaaagttggt cttaagagag atgaattgta
     2821 tctaaactta gaaaaagaga aattaataca gacttttgat atagatgatg aacttgtaaa
     2881 taagatgcaa aactttgcat ttgaagaatc gtatagagaa actgataaaa aaacatatca
     2941 atctatggaa gcatttatac acaatctaaa tacaatgcac tctagagcag gtgcacaggt
     3001 accattttca agtgtaaact tcggaacaga tacttctgaa gaaggaagaa tggtaactaa
     3061 gaatcttcta ttatctcaag aaagaggttt aggtaatgga gagacaccaa tttttccaat
     3121 tttaatattt aaggtcaaag aaggcataaa tttaaatcct gaagacccta attatgattt
     3181 atttaaatta tcatgcagag tatcagctaa aagactattc cctaatttta gctttttaga
     3241 tgcgcctttt aatgcaaaat attataaaaa aggtgaacca gatacagagg ctacatatat
     3301 gggttgtaga acaagagtac ttagtaatgt gtgtggttca gaaacagtta gtggtagagg
     3361 aaacatatct tttactacag taaatttacc aagattgggt ataaaacatg gtattataaa
     3421 taatgaaaag gctaatttag atggtttctt tgaagaatta gatgagaaga taaacttaat
     3481 tatagaacaa ttattggagc gccttgaggt acaaggaaat aaaaagatga agaattttcc
     3541 attcttaatg gggcaaggtg tatggaaagg ttctgatgat ttaggaccag aagatacact
     3601 aaaagaagta ataaaacaag gaacattgac aattggattt ataggtttag cagagtgcct
     3661 tattgctctt ataggtaaac atcatggaga aagtaaagaa gctcaagaat taggattaaa
     3721 aatagtgtca catatgagac ataaaatgga tgaagcaacg gacaaatata aattaaattt
     3781 ctccttaatg ggtactccag cagaaggtct ttcaggtagg tttactaaaa tagataaaaa
     3841 agtttatgga gaaattaaag gtatcacaga taaagaatat tatactaatt cattccatgt
     3901 accagtttat tacaatataa gtgcatatga taaaattgag atagaagctc cataccatga
     3961 attgactaat gcaggtcata taacatatgt agagttagat ggagatccat ctgataattt
     4021 agaagctttt gaaactgtta taaaagctat gaaagatttg ggtataggat atggaagtat
     4081 aaatcatcct gtagatagag acccaatatg cggtttttca ggtgtaataa caagtaatat
     4141 atgccctgta tgtggaagaa atgaagatga aagtgacatc aaattcgaaa gaataagaag
     4201 aataacagga tacttagttg gtacagttga tagatttaat aatgctaaaa aagcagaagt
     4261 aagagataga gtaaaacata gatagtttta tttgggggaa taagttatga aaataagaat
     4321 gtcatctact ataagttatg acagcatagt tgatggacca ggattaagaa tggtaatatg
     4381 gactcaagga tgtattcata attgtaaaga gtgccataat cctcagacac atgatttatg
     4441 tggaggattt tatatggata cagaagaaat tataaataaa gtcaaatcat tgaaattaca
     4501 aaaaggcatt acgctatcag gaggagaacc atttttacaa ccagaaccat tagaagaaat
     4561 agcaagagaa gctaaaataa atgggttaga tgtatggtca tatactggat ttacgtttga
     4621 acaactgtta gataaaaaaa atagagcgta ttttaaaaat ttaaatttac taaagcaaat
     4681 tgatatttta gtggatggaa aatttatagc tgaaaaaaaa gatataagct taaagtttag
     4741 agggtcatca aatcaaagga taattgatgt tcaaaaaagt ttgaaatata aaaaagtgtt
     4801 tttggttgag caatatatga aggatgattt atctatagca gaataaaata taaataaaca
     4861 ggattaaata tatgcatata tttaatcctg tttattttca tataatattt caagcttgta
     4921 taatgtaaca attaaaccaa aagactcatt gtatatttga aattaagttt tttatagttt
     4981 ataggtgttt tatgtggatt acgaatgata tagtattgat acattattta atagattctt
     5041 atgccaagaa acaattaatt tatagaaatt cttaattgtt acaatataaa tatctagata
     5101 agttataaga tactgataaa taatttataa agtttattaa tctaatattg tgtgtgaata
     5161 ttaagtggtc aagtagtcta aaaaatgaaa aagatttaaa aaagtgtttt aactaaacac
     5221 ataagtgtta aattcatgta taagtatagg ttagatacat aagaaataat tatgtaatat
     5281 ctatctttgt aaaaaaatat taaattttgt aatttgtgga taaatatgtt tataatgtgg
     5341 ataatattta atgtaataag ttaaagcaat atgaatcaac tgtttataat gtggataata
     5401 ttataaatgt atgaataatt gcagtattta aaaacaaaaa aagttaaaaa agttgttgac
     5461 tctaaaagaa aaagttggta tagtaatact tgtcctcaag aaaagggcaa acaaataaag
     5521 cataa
//
LOCUS       DAEHWO010000143         5519 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEHWO010000143 DAEHWO010000000
VERSION     DAEHWO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5519
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.146"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            218..1489
                     /gene="serS"
                     /locus_tag="KNP54_003824"
     CDS             218..1489
                     /gene="serS"
                     /locus_tag="KNP54_003824"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBF0894674.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            1767..3272
                     /locus_tag="KNP54_003825"
     CDS             1767..3272
                     /locus_tag="KNP54_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBF0894675.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            3386..4084
                     /locus_tag="KNP54_003826"
     CDS             3386..4084
                     /locus_tag="KNP54_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBF0894676.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            4369..5457
                     /locus_tag="KNP54_003827"
     CDS             4369..5457
                     /locus_tag="KNP54_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894677.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
BASE COUNT         2212 a          555 c          929 g         1823 t
ORIGIN      
        1 atgaagttaa atctagcaat attctcctaa aattaaatta catttattta attaaatata
       61 atttgacaat ggacaaaaaa gtgagtaaaa tataaataaa ataaaaataa caggttcgga
      121 taaagaaaaa ggtttcttaa cctcaagcat aaagtatatt atctaagtta tttgagatta
      181 agagataaat ccaatcttag gtactgagga ggaaaaaatg cttgatataa aaagaataag
      241 agaaaattta gattgtataa aaaaagcaat ggaaagaagg ggcgaaaaag actttaacct
      301 tgatgaagta gttaagttag atgatgaaag aagaaagatt cttcaagaag ttgaagttat
      361 gaaaaatgaa ttaaatacag catctaaaaa tataccaaat cttataaaag aaggtaaaga
      421 tgtagaaaat gaaaagatta aactaaaaga gttatctgat aaaattaagg taatagacca
      481 aaatcttaaa gaagtagaag ataagatgga atacctatta atgagaatac caaatgtacc
      541 acatccagaa gtaccacaag gtgaaactga tgaagataat gttgaagtaa gaacttgggg
      601 aaagactact acctttgatt ttgaatctaa ggctcattgg gaaattggaa cagaattagg
      661 tatacttgat tttgaaacag ctagtaaaat aactggttca agatttactc tttacaaagg
      721 attaggtgct agattagaga gagcattatt aaatttttac ttagacacga atacaaaagt
      781 aaatggatat acagaagtta ttccaccatt tatggcaaat agaaatagtt ttttaggtac
      841 aggacagtta cctaagtttg aagaagatat gtttaaaata gaaggtatgg actattttat
      901 gattccaaca tcagaagttc ctttaactaa tatacatgct aatgaaatac ttaaatttga
      961 acaattaccg ataaattata cagcttatac tccatgtttt aggtcagaag ctggttctgc
     1021 tggaagagat acaagaggtt tagtaagaca acatcagttt aacaaagtag aaatggttaa
     1081 aatagttgca ccagaagaat cttacaatga gttagaaaag cttactaaca atgcggaaac
     1141 tatgctacaa ttattgaatc tgccttatag ggtagtaaag atatgtacag gtgatttagg
     1201 atttacggct tcttttaaat atgatgtaga agtttggatg ccaagttaca ataggtatgt
     1261 tgagatttca tcttgttcaa actgcgaaga tttccaagct agaagagcag gaataagatt
     1321 taaaagagat aaagattcta aagctgaata tgtacacaca ttaaatggct ctgggttagc
     1381 tattggaaga agtgttgcag ctatattaga aaattatcaa caagaagatg gttctgtggt
     1441 tgttcctgaa gttttaagac catatatggg agtttctgtt attaagtaag agttaaatta
     1501 tgtattttta agcaatacaa taatatagag gtaataaaaa ataattaata taaaagtgat
     1561 acaataatat agaagtaata aaaaaatagt taatataaaa gtgatacaat aatatagaag
     1621 taataaaaaa aaataattaa tataaaaatg tgtacaaact aatgaatatt gatatagtaa
     1681 gctatcatat gaaagagtat gtacacattt tttttactaa tttttcacaa tatgaacata
     1741 aataatttac aggaaaggaa tcttttatga aaattcaaaa tactgagtgg ggatatattg
     1801 aatggaaaca tacttatgat gaaaataatc caaaacaagc tatgaatata tacattgcag
     1861 taactatgcc tggtaagaaa cattttaatc atgttcatta tggtcaagag cagatgatat
     1921 atattttaga gggagagggt ttgtatatta taaatggagt ttggaagcca ttttatcaag
     1981 gtatgatttt ttatatagaa tctggtagca cacatgaaac tataaataca ggtgatagag
     2041 aaataaaaga acttattgtt tcaaataatg tagatgatgt aggagagagt gaagttatag
     2101 atattaatcc taataattat ttaaagaaga ccttgataaa ttatagtgaa agtacattaa
     2161 atttgtatgc agcagtagaa tcaattcgtg gtcaatttat agacccgttt aaaattccat
     2221 taattatata tgatgattca tggaatatag ttttaaaaaa tccttatttt ccactttttt
     2281 gttttgaaaa atgtaatcct atgaaatttc ctcaaaattg tgattgtatg aatcaaaaaa
     2341 gtagcaatca atttgtatgt gaatatggga taactatata taatatacca atactgtaca
     2401 aaagcaatag cataggtgtt ataagaggag ggtatgtact attatctgat ttgaatttag
     2461 atacagagca taataattta tatgatattc cagagggagc tgctagaagt ataaaacgcc
     2521 tcttgaaaca aatatctaaa aatataataa atttttgctc ttttaatgat ataagaaagg
     2581 atttacaaga aaaagagaag actatagcaa gaacatatca ttatggagag caacttgaaa
     2641 tgaatttaaa agtagctcaa gatatggtta ctaatttaag aataaatcat cactttttat
     2701 ttaatacatt aaattcaatg gcaagcatag cactagatga tggtagttat gatttgtata
     2761 gtgcaataat agatttatca agaatgttta gatatacaat gaggtctgat ttaagatttg
     2821 tagaattaga atctgaaata ttatacatta aaaattattt gaatttacag aaattacgtt
     2881 atggagatgc acttaaagta aaatatctta ttccagagaa gttatataac ctttctgtgc
     2941 cttttaactt tattcaacct attgtagaga atgcatttac acatggattt agagatattg
     3001 acacagaaaa gcgaattgaa ataattgcaa gattagattc tcagtatgct attatagaga
     3061 ttcataataa tggaactatc ttagatggaa ataatataga caaaataaag gcaggtattc
     3121 gtagtaataa tggtcatggt ttgtctttaa tatatacaaa attcacatct gcttatggaa
     3181 ataattttga tatggatata aagtcgagtg ataatgaagg aacttacata atgattaaaa
     3241 ttcctattga aaattataag gagtatgtat agaacttgtg aaaaattaat aagttttata
     3301 aatgttaaga aatatattag atgtttttat gttgttttat atatcttact tttttatatt
     3361 attaagctaa aagggaggta ttctcatgag aagagcacta ataatagatg atgaagaagc
     3421 tgttctaaaa ataataacac attttataga aatgaaagat atgccaataa aaattgttgg
     3481 taaagcaaca tctggtgatg aagcagtaga taaaatcatt ggtttagagc cagacatagt
     3541 ttttatagat attcaaatgc caatatacaa cgggttagaa gtaatagaaa aaacatctca
     3601 tttatctaaa aaaataaact ttgtagtaat aactgcattt aactattttg aatatgctca
     3661 aaaagctttg agattaaatg taaaagatat actccttaaa ccattggata tgaaagaatt
     3721 tactaagtct gtagaaaaaa ttattggata tcaatatacc aataatgatt tattaaatga
     3781 gatactggaa tatataaatc taaactatag caatgactta aagttaaatg attgtgctag
     3841 attattttta accaatccat ctaatatatc taggattttt aaaagtaatt taaatacaac
     3901 ttttatatca tatctaaatc atataagaat agaaaaatct attgagttac ttgaaaatac
     3961 tacaaaaagt ataaatgaga ttgcagaaat agttggatat aatagcctaa ataactttta
     4021 taaaaacttt aagatagaaa aaggaatgac tccaaaagtt tataaactga acactaaaaa
     4081 ttgaaattga taaataaaaa gtcaatatag ataattgttt gagtgtgtct gaataagtat
     4141 actttaatta tgataaaaat taaagcgctt taaacatatt taataatatt aaaccttata
     4201 aaagctgtac ctatttatat aaaaaaatat atataaataa aaagaaaaag atatacaaaa
     4261 taaaaaaagt gaattaaata ctgtttcaaa aagacagaat tttcatttaa tttactgaga
     4321 gtttatattt cttaaaggaa ggtaacttta taatggaggt aatttaatat gtcagacaaa
     4381 gtgaatatga aaaatattat ctgtattgca ggcgcttatc tagcaacagc aattggttct
     4441 gggtttgcta ctggtcaaga aattctacaa ttttttgcct cacaagggta tatgggttta
     4501 attggagcat taatatcaat ggtattgttt tcatttcttg gtgctgaagt tataactaga
     4561 ggtagagaat taaaacttaa agaaccaaca agaatttaca ctttttattg tgggaagatt
     4621 ttaggaaaat tttacgaatg gtttagtcca atatttttat ttgggattct tatagtaatg
     4681 atttcaggtg caggctcaac tttaactgaa tactatggta taaatcctta cttaggaaga
     4741 gtattgatgg ctgttgctac tttaattaca gtgtctatgg gtttagaaaa attagtaagc
     4801 atacttggac gtattggacc agtgatagca gtatttacaa ttgctgttgg attaataagc
     4861 ttgtttaagc attttgatgg tttatctatg gttggagaag ctatgaaaaa tattgaagtt
     4921 acaaaagcat cagaaagtcc aatcgtttct ggtgtaatat ataatacatt aaatattatt
     4981 gtaatgattg tttttttaac aggaatggga gcttctattg aaagtaaaaa ggatgctttt
     5041 tggggaggtt tattaggtgg aatagtgttt atgactgctg gtatagttat gtatttggct
     5101 atgatttcag atataggaaa tttgtatatg aaagaaatac catcacttta tttagcagat
     5161 aatatatctc ctattgtagg tgtatgtttt tcagttgcat taatattagg tatctacaca
     5221 acagctgttc cacttttatg gtctgtaacc aatagaattg ttgaagatga acatcctaaa
     5281 tttaaattgg taacaacagt aatagctatt ttggcttgta taggaggttt tttaccgttt
     5341 ggtaaactag taaacatttt atatccatat acaggttata tggggctttt aattttagtc
     5401 tgtatggtgt ataaagcaat tacatgtaga aaaaaatcaa cacaaagtca ggaatagagc
     5461 cacttattaa tagtttttat ttaaagaaat tttttatata atccgaattt aaaaagtca
//
LOCUS       DAEHWO010000144         5410 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEHWO010000144 DAEHWO010000000
VERSION     DAEHWO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5410
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.147"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            52..2283
                     /gene="pflB"
                     /locus_tag="KNP54_003828"
     CDS             52..2283
                     /gene="pflB"
                     /locus_tag="KNP54_003828"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBF0894678.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPGALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            2443..3177
                     /gene="pflA"
                     /locus_tag="KNP54_003829"
     CDS             2443..3177
                     /gene="pflA"
                     /locus_tag="KNP54_003829"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBF0894679.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNIDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3299..4969)
                     /locus_tag="KNP54_003830"
     CDS             complement(3299..4969)
                     /locus_tag="KNP54_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBF0894680.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
BASE COUNT         1919 a          785 c          796 g         1910 t
ORIGIN      
        1 attaatttta atagtattat ttatcattta aatctaagga ggaaatactt aatgaatgca
       61 tggcaaggat ttaaaacagg aagatggact aaagaaataa atgttagaga gtttatacaa
      121 ttaaactatt ctccatatga gggaaatgac tctttcttag ctggtgccac tgaaaatact
      181 aaaaaattat gggacgaagc aatggtccta tttaaaaaag aaagagaaaa tggtggtact
      241 ttagatgttg atacaaaaac tgtttctgga atagctgcat atgctccagg atatttagat
      301 aaagaattag aaacaatagt tgggttacaa acggatgccc ctttaaaaag agctgtcatg
      361 ccatatggtg gtataaagat ggttgaaaat tcatgtgaag cttttggata tgaattagac
      421 ccagaaataa aagatatatt tactaaatac agaaaaacac acaaccaagg agtttttgat
      481 gtttatactc cagaaatgag agctgctaga aaatctggta taataacagg tcttccagat
      541 gcttatggta gaggtagaat aattggtgac tacagaagag ttgctctata cggtgttgat
      601 gctttaatag aagataaaaa tgagcaaaag aaatcattag aagtttcttg catggatgag
      661 gaagttatca gattaagaga agaaataact gagcaaatat cagctttaaa tgaacttaaa
      721 aaaatggctg aatcttatgg atttgatata tcaaaaccag caactaactc aaaagaagct
      781 gtacaatggt tatactttgg ttatttaggt gctgttaaag accaaaatgg tgctgcaatg
      841 tctttaggta gaacatctac tttcttagat atatactttg aaagagattt aaaagctgga
      901 atcgtaacag aagaagaatt acaagagtat atggaccatt ttgttatgaa attaagaatg
      961 gttaagttcc taagaactcc tgattacaat aacctattct ctggagaccc aacttgggta
     1021 actgagtgta taggaggtat gggaatagat ggtagaacat tagttactaa aaactcattt
     1081 agaatgttaa atactctata tacattagga ccttctccag aaccaaactt aacagttcta
     1141 tggtcaacta aattacctca aggattcaaa gatttctgtt ctaaagtatc tatagataca
     1201 agttcagtac agtatgaaaa tgatgattta atgagagcat actggggaga tgactatggt
     1261 atagcttgtt gtgtatctgc aatgagaatt ggtaaacaaa tgcagttctt tggagctaga
     1321 gttaacttag ctaaaacttt attatacgct ataaatggtg gtgtagatga gaaatctggt
     1381 gttcaagttg gaccaagatt tgaacctata acttctgagt acttagatta tgatgaagtt
     1441 atgagtaaat ttgaaccatt cactgattgg ttagcaacat tatatgtaaa tactttaaat
     1501 gtaatacatt atatgcatga taaatattct tatgaagcat tagaaatggc attacatgat
     1561 agagatatat ttagaactat ggcttgtggt atggctgggt tatcagtttg tgcagactca
     1621 ttatctgcta taaaacatgc taaggttaaa actattagaa atgaacaagg aatagctgtt
     1681 gattttgaaa tagaaggaga ttatccaaaa tacggaaata atgatgatag agttgatagt
     1741 atagctgtag agttagttga aagctttatg aataaaataa gaaagaataa aacttataga
     1801 aattcttatc caactcaatc tatacttaca ataacttcaa atgttgttta tggtaagaaa
     1861 actggtaata caccagatgg tagaagagct ggtgctccat ttgctcctgg tgctaaccca
     1921 atgcatggta gagatactaa tggtgcttta gcttcattat cttcagttgc taaattacca
     1981 tatgaacatg ctcaagatgg tatatctaat actttctcta tagtacctgg tgctttagga
     2041 aaagatatga ctgaaagaat aaacaatctt tctgcaatga tggatggata cttcgctcaa
     2101 aatgctcatc acttaaatgt aaatgtattt gatagagcta ctttagaaga tgctatggaa
     2161 catccagaag aatatccaca attaactata agagtatctg gatatgcagt taacttcata
     2221 aaattaacta aagagcaaca attagatgtt ataaacagaa cattccacgg taaaatggct
     2281 tagtctttaa atttttatac tttaactaag attactactg tgtaaaaaat aaaaataaaa
     2341 ggctatctta tatttgaatt atttctggta taagatggcc ttttttagag aaatattata
     2401 actattgata aggttattaa aatatattgt gaggtgaact ctatgattaa gggaaagata
     2461 cattctatag aaacgtttgg tactgtagat ggaccaggaa taagatatat attatttttt
     2521 caggggtgtc ctcttagatg caaatactgt cataacaggg atacatggga tattaaatca
     2581 ggaaaagaat acacagttga tgaaataata acggatgctc ttaagtatac ttcttttatg
     2641 aagttttctg gtggaggtat aactgcctct ggtggtgaat ccactcttca accagaattt
     2701 ttaagtgaat tatttaaaaa agcaaaagaa aatgatatac acacttgctt ggatacatct
     2761 ggatttgtag atatagaaac tatagaccca gttttagata atattgattt ggttttactt
     2821 gatttaaaac atatggttga ggaaaaatct attgatttga ctggtgttgg tatggataag
     2881 gcattaaaac ttgctagaca cttagaatca agaaatattc ctgtatggat aagacatgtt
     2941 ttagttcctg gcattactga tgatatagat aatttagaaa aactaggtca atttgtagct
     3001 acattgaaaa atgtagaaag atttgaattg ctaccatacc attctatggg aatacacaaa
     3061 tgggaaagtt taggtatcga ttatgaacta aaagatgttc ctgatgccac taaggaagat
     3121 gtccaaaaag ctagtgaaat aatctctaaa tttggagtga aagtatataa tagttagtgt
     3181 agtatattaa tcctttatag aagacataac aaaatagggt aaagtgtaaa tttttaataa
     3241 acttcaaaac ttccactttg ccctattttt atatactata tatctcattt tatatacatc
     3301 actttgatag ctgaaattta taaaattcag aggcacttac aggtcttcca aataaaaaac
     3361 cctgaataat atctacacct aagcttttta ctatatcata ctcttcataa gactctattc
     3421 cctcaacaca aacttttaaa tttataatat gagctaattt aataatatat tcaagaaaag
     3481 tatattcata actattatat gtaatattct taacaaaact tctttcaatt tttattatat
     3541 taacagacag ttctttaagg taatttaaag atgaatatcc tgtaccaaag tcatctattg
     3601 caatatatac tcctataccc tttaaactaa taaatttatc atttagtaaa tttatatctg
     3661 gtatccaaca attctctgtt aattccaaaa ttaaaaattc aggtcttaat tgatactcta
     3721 ctaaacattc tactataaaa tctctaaaaa aatcttcctt taactgaata tacgatacat
     3781 ttacagatat tttaaagtct ggatttattt tatgccattc tttacactgt tttacagctt
     3841 cttttataat ccacttccca actggtataa ttaaattact ctgttctagt attggtataa
     3901 attcaacagg agatacttct ccataagtac tcgaatgcca tcttaaaagt acctctgccc
     3961 ctattacctc ttttgtaaca gcatttacct ggggttgaaa aaacaactca aaatcattaa
     4021 aattattttc aacgcactct cttagttttt gttgcattga aattaccttt agtttatttt
     4081 catagagctc ttgtgaaaaa aacttaattc tatttttacc actaattttt gctatatcca
     4141 atgcaatatc agcatgttta aataaatcta aataattatc tccatcttct ggatacatag
     4201 caacgcctgc agtcactgtg caatagtact tatttgattc aatttcatgc tgagtatttg
     4261 tatacatctg tatcttttca tatattttct ctatagtttc tttagtacac atagggtaaa
     4321 aaaatgcaaa ttcatctcca tctaacctat acaatcttac atcttttgga agatattcta
     4381 atacttcagt agcaattgca cgcaatactt tgtcaccata agaatgtcca tatttttcat
     4441 ttatattttt aaaattatca atatccataa taaacatagc accattttta taaattttct
     4501 cttttataag ataattcatt ctatgttcaa attgttctct attccacgtt cctgtgatag
     4561 aatcaaattt atttttttca ccaatattct ttattctccc gactagaaat atagtttttg
     4621 ggtcatccga cacataaact ttacctctac aagaaatcca tactatttct ttatatttat
     4681 taatcaacct atattctaaa ttgtgctcac ctttttttcc atgtagtaat tcttgtatat
     4741 catctttcca tatttgaaca tcatccggat aaacaatttt actccaacaa ttgaccaaat
     4801 cagattctat ctctttactt aagttaaatt catcaaaaat tgctgaagaa attttaaatt
     4861 tattcctatt tatatcccaa aaaaatatat aatcttctgt actttgagat aaaagttcaa
     4921 agaaaatttc tatatggtct aaacttaaag agttcgattc ttctctcatc ttttccccct
     4981 acaatattac tattagtgta gtttaatcaa caaaatatcc ttatttagat tatactattt
     5041 tactaatttt ttgtctcatc aaacacattt ccccaacttt agttatctta tcaaatctct
     5101 tactcttaac taagtttttt gagattcata aagtaatttt tctataatca ttactggtga
     5161 tttattttta cctgctaaaa caccatgtta aatcatttat taaatcattt tctcttaaaa
     5221 ttctattttt cgttatataa agagttatca gttctttatt ctataaaact tttctattac
     5281 tcttgaattt attttatttt tttcttcgcc tattctcttt ggatttggta ttgcttttct
     5341 atagattttg gcaaagaagt gtctcttcct ataatataag attttgatat ttcttcatca
     5401 tctataaatt
//
LOCUS       DAEHWO010000145         5366 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEHWO010000145 DAEHWO010000000
VERSION     DAEHWO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5366
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.148"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            162..1223
                     /locus_tag="KNP54_003831"
     CDS             162..1223
                     /locus_tag="KNP54_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBF0894681.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            1314..2927
                     /locus_tag="KNP54_003832"
     CDS             1314..2927
                     /locus_tag="KNP54_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBF0894682.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            3202..5187
                     /locus_tag="KNP54_003833"
     CDS             3202..5187
                     /locus_tag="KNP54_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBF0894683.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            5192..>5366
                     /locus_tag="KNP54_003834"
     CDS             5192..>5366
                     /locus_tag="KNP54_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBF0894684.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVL"
BASE COUNT         2217 a          519 c          952 g         1678 t
ORIGIN      
        1 tatacataaa aaataaaaaa ttgtcgcttt aaagtataaa acagattata tgttaataat
       61 gtggtgaaat tatacccata tataaataaa ataaaacaaa taaatagcta attaaggaga
      121 aaatattttt tattttttgt ttaggataaa taaattttat tatggaaaaa agaaaaagca
      181 tacatcttca caaactgaat atttatttaa tagggggagg tgatagattg tttatcacag
      241 tggtattatt tttagtaggt ttcctattaa ttactaaagg cgcagatatc tttataaatt
      301 gtactgtaga gataggtaaa aaaacgaata tatcagaaat tatacttgga gctactatag
      361 ttagttttgc aacaacatta cctgagttta cagtgtctct acttgcttct attgatggtc
      421 atactactat gagtttagga aatgcagttg gttctataat atgtaataca gggttagcat
      481 tagggttggt tgtttttata agtccattta atgtagataa aaaaatgttt ttttctaagt
      541 ctttactatt aatagtatcc gttatagttt taattttatt gagtttagat ggagttataa
      601 caagaggtga ttcattatta cttataataa tattaatctt ttatatggtt aataattata
      661 gaagtgtcgt tggaaaatct gatactaaaa atagaaatat taaaaataac actattaaag
      721 acatatctac taaaaaaggg aaaaattata gaggtttttc cgtattagaa attgtaaaaa
      781 tactattact ttttgctaca ggattgataa tgatgataat aggttcacaa atccttatag
      841 agagtggagt aataatagct agttttttaa atatacctca aggtatagta agtttaacta
      901 taatagcact tggaacttct ctgccagaga tagtttcgtc gattactgct ataagaaaaa
      961 atcatcatga aatatcagta ggaaatattt tgggtgcaaa catattgaat atagtatcag
     1021 taatagctgt atcagcaata ccaaataaca taccaatact atctcaaaat agacaattgg
     1081 atataccatt catgatatta ttattattaa tagtaataat accaacactt aaatctaata
     1141 aacttagtag aatacaaggt atattgatgt tattcacata ttttctgtac atatcaattt
     1201 tgtatttcat gtatattatt taactatact gtttaaaata ttaattgcag aatatcctaa
     1261 aaaagtatat aatggatagg ttaagattaa ttgataacgg agaggaataa tatatgaata
     1321 taacaaagtt tgaagattta ccaataagtg agggaataaa aaaagctata gctgaaatgg
     1381 ggtttgaaga accatctcct atacaagcac agtctatacc tgcgattttg tcaggtaaag
     1441 acgttatagg acaagctcaa actggtacgg gaaaaacagc tgcttttagt atccctatac
     1501 tagaaacaat agacccaaat aatagaagtt tacaagctgt agtgctttgt ccaacaagag
     1561 aactggcaat acaagtatca acagaaataa gaaagttagc taagtattcg cacggaataa
     1621 agacattacc tatatatggt ggtcagccaa tagatagaca aataaaatct ctaaagagtg
     1681 gtgtgcaagt tgtaataggt acaccaggac gtacaataga ccatatcaat cgtaaaacat
     1741 taaagatgga taatgtaaaa atgattatat tagatgaagc agatgaaatg ctagatatgg
     1801 gatttagaga agatatagaa atgattttaa gtaagattcc agaagaaaga caaacaactt
     1861 tcttttcagc tactatgcca agaggaattt tggaattaac taagagatat caaaaagacc
     1921 cagagcatat aaaagttgtt agaaaagaac ttacagtttc aaatacaaag caatactata
     1981 tagaaactag gtcatcaaat aaattagaag tattatgtag attagtagat gtatatgacc
     2041 ctaaactatc tgttgttttc tgtaatacta agagaaaagc agacgaattg gtaggagatt
     2101 tacaagcaag aggatatttt gcagatgcat tacatggtga cttaaaacag actcaaagag
     2161 atatagtaat ggataagttt agaaatggta caatagatat acttgttgct actgatgttg
     2221 cagctagagg tatagatgtt gatgatgttg aatgtgtatt caactatgac ttaccacaag
     2281 atgaagaata ttacgttcat agaattggta gaactggtcg tgctggtaga gaaggtatgt
     2341 catttacttt tgtatttgga aaagaaatga gaaagatgaa agatatagaa agatatacta
     2401 aatctaaact aataaagcat aatataccaa caataactga tgttgaagag aaaaaagtag
     2461 gtactttctt tgcacaagtt aaacaaacta tagaagaagg tcacttaact aaacaattac
     2521 aatggttaga aggtttctgt aatgatgaag attatgcaat ggttgatata gctgctgcac
     2581 ttgtaaaact atctctaggt gaagaaatga aagaagaaat aatagaagaa aaacctagaa
     2641 gagagcgtgg agatagaaaa ggtggtactg gagctaaaga tggtatgatt agattattta
     2701 tcaatattgg tagaaatcaa agagtacaag caaaagatat agttggtgcc atagctggag
     2761 aagttggaat accaggtaaa gtagtaggta ctatagatat atatgataag tatacttttg
     2821 ttgaaatacc taaaaaagat gcaaaaacag taattgaaaa gatgaaagat attaagataa
     2881 aaggtaataa gattaatata gaaaaagcaa ataagaagaa aaaataacgt atagtataca
     2941 aaactataat tagaaaatat ataaaataat atattggata tttaaaaagc ctgatgtgtt
     3001 ttcaaaacag atagtagata atctgtaaga gttaacagca taaggctttt cttgttttat
     3061 atgatgttat aattttccag attgttgtga aaaatgtata ttagttcctt tttttcaaat
     3121 ctgatttgaa aaagagaata ttaattatct atatagttta gattataata aaaaatgtaa
     3181 gataacaaag gggagaaaaa gatgtcaatg acttatatgg accctagggt ttttttgatt
     3241 ttagaaatgg tgttagaaga agacacaaat actctagaac aattttcaaa tgttttgggt
     3301 gttagtacta ggactatcag aaactatata aaccagatta atcgagaatt aaaaggtggt
     3361 attgctaaaa tagttaaaaa tgaaaaaggt acatatagta taagaattga ggatgaaagt
     3421 aaattaattg agattgtaaa ttttaataga ggaaagctat caaattttat aaatttaaat
     3481 tcacctgatg aaagaataaa ttatgttctt gatattttaa ctatgaccaa caatccaatt
     3541 accatagatg atttggctga agagatatgt ataggaagaa caacattaat aaaggattta
     3601 aaaaaagcag acagaatttt agctgaatat gatttagaat taaaaaggaa gccaaatata
     3661 ggtatgattt tagttggtga agaaatggat ataagattat taatccttga tagattgtat
     3721 gaaaattata ttgatgtctt ggaaaacgtt aatcagataa atttagttaa agattatgat
     3781 attgaatgtc ttagagatga attaaaaaag ttatttaaaa aagaagaact ctacataaca
     3841 gaacaggtct tgagagatgt tgaaagatat ataatcatgt ctgtcttaag aaatctaaat
     3901 gggtacaaat ttgaaaagat agataagaga tttgaagtga taagatgttc agatgaatat
     3961 actttaggat taaagctcaa agctttattg gaaaagatat ttaatatagt tttaaatgaa
     4021 aaagaaacca tatttttgac aatgccatta ataggtagaa aagctcctag tacaaaatta
     4081 gcacttagca gtataaagat aaatgatagc gtaaaggaag ttgtagatga agtaactagt
     4141 tttttattag agacctcagg gattgatttt aaagaagata aaaagcttat agaaaatttg
     4201 gaatatcact tgtattttgc acttaataga atgagattca acataagggt aaaaaatcct
     4261 cttttacaag aaataaagga aagatataca tttccatata gtgttgcaaa gatagctgca
     4321 atgataattg aggaaaagtt tgacttgaaa atatgtgacc acgaaatagg atatatagca
     4381 ttacattttg gaagttattt tgaaaaaaat tcaagaaaag ttctaaatgt aaatagggta
     4441 gctgttgttt gtggaacagg tcttgggact gcacaactta ttagaataaa gataggaaaa
     4501 atacttggag aaagtgtaga agtaaatact ttttctgata tagaagctaa agctaattta
     4561 gatttattaa agtattatga tttagtattt acaacagtag atttcaaaac agacttagat
     4621 gttccaattt ttagagtaaa tgcgttattt aatgaagaaa gtataaagaa agagatagaa
     4681 aatgcaatac ttttgaaaaa tagtataaat cttaagtcta taaaaaagat tgaaaaaaat
     4741 atccctttta taggtaaatt aattgaagag gataagttct ttatattgaa taagagtacg
     4801 tttatggaaa atttagaaga tatgttagaa aaattagttc ataaaggaat tattgatata
     4861 gagttcaaaa aaaaggtatt aaaaagagaa aagaaatctt caacagcatt agataattat
     4921 atagcattgc ctcactcagt taatactaat ggggaaaatc tttatctggc atttggaata
     4981 ttagaaaaac cagtgatttg ggatacaaag gaaattagaa taataatatt gatgataatt
     5041 ccagataaga atgtagatag tacagacctg ataataaaaa gttatgaaga agtacttgaa
     5101 gtagggagag ataaaaagat ggtagaagaa cttgctaagg caaaatcatt tgatgaattt
     5161 tataaaataa ttaccaagag gaggtaataa tatggaccca gtaattttta ttatagcatc
     5221 acttattaca gtgtatttat taaatatttt tcttggatac ttacagctta aagattttaa
     5281 taaaaattat attgaactaa aaagaaaagg aagagtggca attggcagaa aaaaaggaag
     5341 aatttcatcg ggtacaattg tgttga
//
LOCUS       DAEHWO010000146         5365 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEHWO010000146 DAEHWO010000000
VERSION     DAEHWO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5365
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.149"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            106..1083
                     /locus_tag="KNP54_003835"
     CDS             106..1083
                     /locus_tag="KNP54_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894685.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTIGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            1084..2055
                     /locus_tag="KNP54_003836"
     CDS             1084..2055
                     /locus_tag="KNP54_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBF0894686.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            2207..4249
                     /locus_tag="KNP54_003837"
     CDS             2207..4249
                     /locus_tag="KNP54_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBF0894687.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            4510..5352
                     /locus_tag="KNP54_003838"
     CDS             4510..5352
                     /locus_tag="KNP54_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBF0894688.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
BASE COUNT         2146 a          548 c          931 g         1740 t
ORIGIN      
        1 agaaaaaaat aataaaatgt aagaaaatgt tgtaatttaa atttttataa aatacaatca
       61 aaaggtgtat gttatcttaa gtaattttgc tgagaggaga aaataatgag taaagcacta
      121 attgaggtta aagatttaaa agtttatttt catacagata aagggattgt aaagagtgta
      181 aatgaagtaa gttttaatat aaatgaaggt gaaactattg gaatagttgg agaatcagga
      241 tgtggtaagt ctgtaacagc catgtctttg atgaagttac ttccaacatc aaaaatagaa
      301 ggtggagaaa taatctttcg aggcaaagat attttaaaga tgaatgaaga tgaacttatg
      361 ggaataagag ggaatgagat atcaatgatt tttcaagaac caatgacatc tttaaaccca
      421 gcgtttacta ttggaagtca aatcattgaa ggtattatga tacatcaaga tttatcaaag
      481 gaagaagcta agaaaaaggt aatcgatatg ataaaactgg tagaaatacc aagagctgaa
      541 gaaatatata attcatatcc acatgaatta tcaggtggaa tgagacaacg aataatgata
      601 gctatggctt tatcatgtaa tccaaaatta cttatagctg atgaaccaac aacagcttta
      661 gatgttacta ttcaagctca gattttagat ataatgaaaa atataaaaga aaaattaaac
      721 acatctataa tgatgattac acatgatttg ggagtagttg cagaaatgtg tgacaaagta
      781 ttagtgatgt atgctggcaa aattatagaa gtggcagagg ttgttgaatt atttaaaaat
      841 ccaaaacatc cttatactat tggacttcta aaatcaaagc ctgctcttgg aaaaaacaaa
      901 gataaaagat tgtattcgat tccaggacaa gtaccaaatc caattgggat gccagattca
      961 tgttatttta gtgatagatg tgaaaaagta tgtgataaat gtagaactca gatacctcct
     1021 ttaatagaat tgaatagtgg tcatagtatt gcatgttggt tatataaaaa ggaggagata
     1081 taattgaaaa aagaagagag tttattaaaa gtagaaggtc ttaaaaagta ctttgaagtt
     1141 aaatctggat tatttgataa ggaaattaaa tgtgtaaagg cagtagatgg aatttctttt
     1201 gatttaaaaa aaggagaaac tttggctata gttggagaat cgggatgtgg aaaatcaact
     1261 gcaggaagaa ccattcttag attaattgaa aaaactgaag gtaaagttga atttaatggt
     1321 gtagatatat ataagttaga gaaggaagaa cttagaaagt taagacccaa aatgcaaatg
     1381 atatttcaag acccatatag ttcattaaat ccaagattaa atgtggaaca aataatatcc
     1441 gaggcagtta tagaacataa tttagtgcca aagaatgaaa taaaagataa tatattaaat
     1501 gttgtagaaa gttgtggtct ttctaagtac catttaaata gaaaaccagg tgagttttct
     1561 ggaggtcaaa gacagagaat aggtatagca agagcattag cattaaatcc agaatttata
     1621 gtttgtgatg aacctgtttc tgcactagat gtttctattc aatctcaaat tataaattta
     1681 cttatggatt tacaggataa atataaactt tcatatttat ttatatctca tgatttgagt
     1741 gtagtaaatc atattgcaca tagagtttgt gttatgtatc taggttctat aatagaaatt
     1801 gcaactaaag gagaacttta cttacattct caacatccat atacaaaagc gcttatgagc
     1861 gcagtaccaa tacaagaccc tacaattaag aaaaatagaa ttatattaaa aggagacata
     1921 ccatctccaa caaatccacc aagtggatgt aagtttcata caagatgccc ttattgtaag
     1981 gaaatatgca aaaaagagat tccagtttta aaagaaatat caagaaatca ttttgttgca
     2041 tgtcatctag tatagatatt tcaaaaatta aatttgatgt atataataag aataatagaa
     2101 taaactgaaa atttttttga ttaagatggg atttcatgct gttaatatta agttagttga
     2161 tatataagtt taatctataa tattattatt gaaaagagag gtagttatgt caattttagt
     2221 aacattgttg ggattattgg tttgtacaac gatttcaact gtatttagca aaaagtggag
     2281 taatattcct cttgcaatat atcaaattgt actagggatt atattgtcta ttttgccatt
     2341 taaattctca ttttcattta atccagaaat atttgtaata tgtatcatag ctccattact
     2401 attcagtgaa ggacaaaatg tatcgagaaa agagctatta gagctcagaa aaccaatttt
     2461 gcttcttgca tttggtttag ttttaataac cgtgtttgca ggtggaatct ttatacattt
     2521 tcttattcct gggatgccat tatctgtttc atttgctttg gcagcagtaa tatctccaac
     2581 tgatttagta gcagtaaaat caattacaca aggattaaat tttcctaaaa atatgatgag
     2641 tatacttgaa ggtgaatctt tattaaatga tgctgctgga gtagtagcat ttaaggttgc
     2701 agtacttgcc acagttacag gagttttttc aatagaagag gcagggattc aatttatgat
     2761 tacagctttt ggaggaataa tagtaggaag tattttagga tacataatta taaaaataag
     2821 acttagttta cacaagtgga atttggaaga aattccaatg gtaatagtta tacaaataat
     2881 gactccactt tttgtatatt ttgtagcaga agaaatagga gtatctggaa tcctagctgt
     2941 tgtaatggca gggatagctc atggaattga aaaagagcat ttacaaaata caactactaa
     3001 attaaggata atatcagaca atacttggta tgttttggag tatgtattga atggatttgt
     3061 ctttacactg cttggttttt tgttaccaag tatatataca ggacttagta gtaaaaatga
     3121 aaatatggca ttggaattga cttttatttc tactttaatt gtacttattt tatttgttat
     3181 aagatttata tgggtatatt tatggcataa ttcttttata aaacctaaaa agaatccttt
     3241 aaataatttt tttgtaggtt ttttaggttt taaggatgaa gaagttgtaa aagagagtat
     3301 ttctaaatgt aaatactcac taatagttgc tacttgtggt gttcatggta catttacact
     3361 agcaactgcc ttatctatac ctttttattt ggctgataaa gatgtatttc caatgagaga
     3421 tactgtttta tttatatcat cagaagttat tcttataagt ttagtattgg caacagtttt
     3481 actgccaaga ttattaaaaa ataacgtaca agagtcagaa cctttattat ctgataaaga
     3541 ggcatataaa ctaattttga aagaagccat tttaaaactt agtaatgaaa aagcacaaga
     3601 agtacaacca gttatacatg atttaaatga acagttggta gactcagaaa aaggaatact
     3661 aaatactcca gataataaac ttataagtat gatgattgca gaagcagacc aacagggatt
     3721 attagctgtt ttgaaactat tagaagatgg taaaatttct gatagagcct ttaaattgta
     3781 tagattttat attacaaaat caagaaaatc tgttcaaaaa tctatattta aaattgtaaa
     3841 attaaaaata agcatgtgga ttataaatag aaaagtaaag aaagaagtaa aagaaaaaat
     3901 tacaaaaata gtatctgaga ataaagaaat aatcaaagag tttcaccatg catatgcact
     3961 ttctactaaa actgctatat catttataaa taaaaatact gatgaagata acagacatga
     4021 ggccttaata gcaatcagat tctataatcg ttatttgaat tggattacta gaaagattca
     4081 aaatgatgat aagtttgagg caagagtaga atactacaga gtaatggcga tacaaagtca
     4141 aagagacagt gttcaacaat tagttgaaac taagcaaata tcaagagaag tggctaaaga
     4201 gttattggaa aatattctct atgatgaaat gatgatgata gaatcataaa tataatggaa
     4261 taaaatttga tttttgatgt taaaattaat actaaaaaat aggaaatagt tttcaataat
     4321 ttacttgaca tatatattta tttataatag aataaaacca taaattgaat acaatatata
     4381 agcgttaaca agctggattg ttactggtaa gcaggcaata cctaggttaa ggtatacagg
     4441 tgaattgtat cttaatttag gtattttttt atgaataagg gaaattgtat tttgggagag
     4501 atattgatta tgattattca acaaatttat aataataatg ttgtattagt tttagatgaa
     4561 aatataaaaa aagaattaat attaacagga tgtggaattg ggtttcaaaa aaagaaaggt
     4621 caagaaatag ataaaagtaa aattgaaaga acttttgtaa tacaagatga aagcttttta
     4681 gataaaatta gtaaactagc aagccaggtt gatgagaaat tttttgaggt tagtactgaa
     4741 ataattgctt atgcagagga gaatttgaat actaaacttt atgaatatat ttatgtagca
     4801 cttactgacc atattgcatt tgcaattaaa agatatcatg aaaacataac tataaagaat
     4861 gatttactac atgagataaa aagaatacat aaaaaagaat atgagattgg gaaatgggct
     4921 gtagattata taaataaaga atttgatgtg aaatttccag tagatgaagc tggttttata
     4981 gcaatgcata tagtaaattc aaactataag ggaagttcaa aggaatcact gttaattact
     5041 aaaattgtaa aagacatact aaatattata agatattatt atagagttga atttaaagaa
     5101 gatgatataa attatgatag gcttctgact catttaaaat tctttgcaaa acgattagta
     5161 aaaaaagaaa aaatcaatga tacaaataat gaaattatag atataattaa agtaaagtat
     5221 gaaaaggatt atgattgtgc atataaaata aaaactcatg tagaaaagaa ttatgattac
     5281 tatgtaagtc aagatgaact actttattta acattacata tcaaaagagt tatatctgta
     5341 ctgaatttat aataaagagt agttt
//
LOCUS       DAEHWO010000147         5333 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEHWO010000147 DAEHWO010000000
VERSION     DAEHWO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5333
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.150"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            444..908
                     /locus_tag="KNP54_003839"
     CDS             444..908
                     /locus_tag="KNP54_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0894689.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIIGLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(1175..1819)
                     /locus_tag="KNP54_003840"
     CDS             complement(1175..1819)
                     /locus_tag="KNP54_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894690.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMVPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(1749..3038)
                     /locus_tag="KNP54_003841"
     CDS             complement(1749..3038)
                     /locus_tag="KNP54_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894691.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(3035..3907)
                     /locus_tag="KNP54_003842"
     CDS             complement(3035..3907)
                     /locus_tag="KNP54_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894692.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(4437..4928)
                     /locus_tag="KNP54_003843"
     CDS             complement(4437..4928)
                     /locus_tag="KNP54_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBF0894693.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT         1925 a          779 c          591 g         2038 t
ORIGIN      
        1 ttttttgtaa ctactagaat agtaatttag tagttattgt atctctaaag tttaagcatg
       61 gatagatata catttgataa tttgcctata atttacctac tacttggatt attggagcaa
      121 atacaatata ttaataataa gttcctaaaa ccaataaatt aactaataca cataaagata
      181 ttgatgttga ttatacaact ataagaaacg gatttaacag aatttaatca agctaagaaa
      241 ttatatatat atcgtgatgt ttttgaatta gaaggtaatt caaaattagt ttatagtctt
      301 ctgtcaatcc aataaaaagt acagggtaca agaattgtta gtaaaatttt taaagatttt
      361 atggataaat ataaatagtt ttacttattt tctaaaactt taaaatacca ttaattacct
      421 taaatatttt aataggagga catatgaatt taaataaagt taaatttact gaagaacatg
      481 ctattgaagt tactaattgg aaatatgaag gtaaatattc aatatacaat ctacctccat
      541 gggaggaaat taaaaagaag aatttttcac tagcaaaaga agataaaaga aaaaatttta
      601 taagttttat aaatgacaat aaagaattga taggttttat aaacttatta gatgaaggaa
      661 gctctgtatt ctttggtatt ggtatgaaac cgaattattg tggaatggga attggtaaag
      721 aaataattgg cctaggatta caagaatgta gaaataaata tagtactaaa ccaattgtat
      781 taaatgtaag aacctggaac atgagagctg taaaatgtta tgagtctcaa ggatttaaaa
      841 tagttgagac taaggtacaa aaaacgcatt taggagatgg agaatttttt gttatgaggt
      901 atcaatagtt tataacaata gtcttattgt taatacaaca attaaaatga aaaaatacat
      961 atgtgtaggt catagcaata agtgtctttg aaatataaat ttgagagctt ttgataaaat
     1021 tttgtataca tatatatttt atactacgga tatataaatc tatctacata tataaagaga
     1081 ttgtaagtag gtttgtgtat ataaaaatag atttatattt cataaatgta ctttttattt
     1141 gtattacctt tattttatct aagctctcat tttattatct aatcttcctt tttactggtt
     1201 ttattaagag agatgcaatt atcaacacaa cacttccaag tatcagccaa tatttctcat
     1261 caaaactacc ttgactcata gacattataa aaaattttcc aacatacttg cctttagtca
     1321 tcatatttaa aattaaatat cctatagata tcatataacc tatgattgta ttattaaata
     1381 aatttgagaa aaacattcct aaacttccta taaacatagc tgatgcgaaa cttccaataa
     1441 tatactcaac tactggaaaa ttacatccaa gatatattaa aacatttaca aaacctatga
     1501 ttaataccac tatacctata attgacatca gtatcctaat taattgtaca ataacttgag
     1561 ataatgcttt tgaagatact atctcatcaa tttcttttga ttgctctagc gaaaatacag
     1621 gtaccaacat tactatccct attattgcaa cataattttc taaacatata gctgttgaaa
     1681 ttctgtctaa attagctact ccttgtatta gaggaaccat acatagcaat ataattgaac
     1741 atattaaatt agttaaagtg cttaatttga agttttcttt tattagaact aaacagtttt
     1801 gaaaactttg cccaaacatc aagattcccc cttctttttt gctcatataa gaatatagct
     1861 aacaaaacaa gcaccaatgc tcccaagctt atcacaattc tattaatcat aatttgattg
     1921 aagttttgta taataatatc cccatttaat acactattat gtcttatcat tagccccatt
     1981 gttgaataat cacctttgag tcctgtagaa tttatactgt aaagccacca aattaattgc
     2041 acaataattg ctactggtgt atctgttaat atagtaatac tcattcctac agctgtaact
     2101 atcataagag ttggtagtat ccaccataat gtatatttta taaatgctaa gttatcaata
     2161 gatatacctt tatctttagc aaagaaaatc aaaggaagta aatctttcat acctaaaatt
     2221 aatacaggca atatcatcat aaagacaagt gcaaaatatc ttgataaaac tattttgcat
     2281 gaagatactt gttttgaata aataatctct ctcattcttg aacgcttatc tttaagtgac
     2341 ataaaaactg ccacaaatac tggaaatata cttaaaacta tacctatata atcgcaaaaa
     2401 attcttgcat acccattact aactttatct ttttgtattg tatagttgta attcttcata
     2461 gcttcatcat aggtaactgg aactactcca aatctttgta acttgtcaaa agcatatgca
     2521 gaccctcctc ctaaaatgtc gtctactctt tgcattattt cttcaaatct ttcaagagat
     2581 actttagaat aatctatttt tatactttca tcagttttcc aaagtgaatt tatttcgcta
     2641 atacttttac cagttatttc ttctatatat ttttctatgg tcttcgtttt attttggtct
     2701 aattttatat acttaactac ccctgttgga tacgttgtat atgtgttttt ttgatattct
     2761 ctaattaggt ttatagttgc atttggaatg accttttctg ttttcataga ttctttttga
     2821 ccatatggat attgattgtg tacagaataa tattcctcaa tattctctac tttttgtgga
     2881 gcaactaatg gatttccatc attaggaata tttttactta catcatttga aactgaactt
     2941 ccaagttgag aaatatagaa aaaaactaaa actacaataa aaatataata taccatactc
     3001 tttaatatat ttttacattc ttttataaat agattcatat attatctcct cccattataa
     3061 gcatatagcc atcttcaata gttggattac aatttactgc tgtctcaaaa ggtttatcat
     3121 ctgatataat cctaagtata gcctttccac catgagtcaa cattcctata actataaatc
     3181 tactttttat attttcaatg tcttttttat ctacttcaat actatatact ttcccttcag
     3241 ctagttttgc taatgcttct gttgagccat tgtatatgac ttttccacta ttcaatatag
     3301 ctacgttttc acatgtagct tctatatctc caacaatatg tgtagataaa ataacgattc
     3361 tatcatttgc aatttcgcat agtaaatttc taaatcttat acgttcttct gggtcaagac
     3421 ctgctgtcgg ctcatctact attaaaactc tgggattatg aattaatgct tgtgctatcc
     3481 caagccttct attcatacct ccagataaag attttacttt cacattttga taattagtaa
     3541 ggtttacttt gcttaataac tttgctataa tttttcttct ttttcttagt ggtatatccg
     3601 ataaaactgc taaataatcc attgctttat atactgtcat gttaggatac attgaaaaat
     3661 cttgtggcaa ataaccaacc atatttctaa tttccttagt attctcaata ggaactccac
     3721 acatatgtat tgaaccttct gtttttgata ataaagtggc taaaattctc ataaatgtgg
     3781 tttttcctgc tccatttctt cctaaaagac caaacatacc actgtcgatt tcaagattta
     3841 tattatcaag agcttgtttt ttcccaaatc ttttactaag attggatact gctattttca
     3901 tttccatata taaatacacc cccagaaaca attttataga attttatttt tataaatttt
     3961 tactgtattt tcataataaa ttctaaaact taagatatta tttataaatt tctaaatttt
     4021 ttctaaagat tttaattttt ctgtttttaa ttaaattaaa gtatctttgt ttctgaaatt
     4081 ttttaagttt atgaagttat aatttaatat atatttattt tatttgtgag tctattttta
     4141 tatataatga aaaatgtgat aagtatccaa aagaattact ggatataata ggatagggta
     4201 tttagccttt taagataaat aaaaatatct acaactatat attgcaaaaa tttaaaacta
     4261 atttatatat gctaatataa atatttataa agacataaga caaatttacc tacagattta
     4321 aatttaactt atatatttta aaaggctaat ataatatgta ttttcttcta tacaatcaaa
     4381 aggcttcata tctaagatat gtgatgacac taatattcac aattttttag taattatcac
     4441 attataaaaa atattacagc tagtccatca tcagatgctt cttgtataaa ctttttaagc
     4501 tcaattagat ttgcccatac atattcaaaa aaatcatctt cactctcatc attcataaca
     4561 ggataaatat tattttctaa catctcatta atattaaatc tttttctaaa tgcttgttct
     4621 tccaaactgt tcattgcttt tgatagtttt tttacatcat ttgctgtaat caacatgaca
     4681 ggaaattctc catcaatttc cataagtatg tttccactta gtactaattt gctaaatata
     4741 ttatcatcat ctccaccaaa aggacaacct gtcaaagtaa agtgaatggc atgccatgct
     4801 ttatcaatat tgatagtact attttcgttg gcatcttcaa aaacaaaatc ttgtaagttt
     4861 tcttctgctt gctgtaattt aaaaacattc tcttcactta ttttagtata acatcctatc
     4921 atccccataa ttacattcct cctaagtagc gtttttttaa ttgtaactta taattaaact
     4981 tagttacaat aaaatatatt gagaaaagta ttatttcatc ttaaatttaa atacctatat
     5041 tatcaactaa aattctgtgt ttatagcgta agtattatta ttttttccta aaaattaaat
     5101 gaatcagaag ttctataggc aatattgact ataaataaga actattactt ttaaaaaaaa
     5161 atttaagaaa ttatactgta gaatcatgct ctacttatta gctttaaata aaaaataaat
     5221 catgttctca aattaaataa taaataacaa taaatttaaa ttttaaacta taagagtttc
     5281 tgaagtgtta ataagcatac caataattat atgtgtaaga atttgattta ata
//
LOCUS       DAEHWO010000148         5317 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEHWO010000148 DAEHWO010000000
VERSION     DAEHWO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.151"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(121..1035)
                     /locus_tag="KNP54_003844"
     CDS             complement(121..1035)
                     /locus_tag="KNP54_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HBF0894694.1"
                     /translation="MELVKNIHKNKSKDEIFKELLENLKGTIASWDYYVNWNKALENT
                     RKIEVQLNILNYLIGKEDIENETKNLLKEYPEVLSVIPIVIASRDNEFKILDPSDEDM
                     FKYKLFNFKKRKSISDEESELATEFLKKIKFLDLLKQKNIKNLVDYVFGVEVGLDTNA
                     RKNRTGSSMETLVERYVKNMCEKNNWSYLTQATVKKISEKWSIEVPTDKSKRKYDFAI
                     NNNGKIVLVEVNFYNGGGSKLKSVANEFTKLDKYIKDGGFTFCWITDGLGWLESSIPL
                     RDAFDKMDYIFNLDMVDKGSLEYIIKNL"
     gene            complement(1054..1968)
                     /locus_tag="KNP54_003845"
                     /pseudo
     CDS             complement(1054..1968)
                     /locus_tag="KNP54_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008909111.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
     gene            complement(2396..2745)
                     /gene="ssrA"
                     /locus_tag="KNP54_003846"
     tmRNA           complement(2396..2745)
                     /gene="ssrA"
                     /locus_tag="KNP54_003846"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2903..3358)
                     /gene="smpB"
                     /locus_tag="KNP54_003847"
     CDS             complement(2903..3358)
                     /gene="smpB"
                     /locus_tag="KNP54_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBF0894695.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            3978..4805
                     /locus_tag="KNP54_003848"
     CDS             3978..4805
                     /locus_tag="KNP54_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBF0894696.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
BASE COUNT         1814 a          848 c          570 g         2085 t
ORIGIN      
        1 tattattgat attttataaa tataattata cttatatctc atactcaaat attttatata
       61 atatataagt ctaaattaac ttgcaatata aaagcgcctc ttaatatagg cgctataatg
      121 ttataaattt ttaattatat attccaatga acctttatca accatatcta aattaaatat
      181 ataatccatc ttatcaaatg catctcttaa tggaatactt gattcaagcc atcctaaccc
      241 atctgtaatc caacaaaatg taaaacctcc atcttttata tacttatcta acttagtaaa
      301 ctcatttgca acagatttta acttagaacc tccaccatta taaaaattaa cttctactaa
      361 aacaattttt ccattattat ttatagcaaa gtcatacttt cttttactct tatctgttgg
      421 aacttctata gaccatttct cacttatttt tttcactgta gcttgtgtta aataactcca
      481 attattcttt tcacacatat tctttacata tctttctaca agagtttcca tactacttcc
      541 agttctattt tttctagcat tcgtatcaag cccaacctct actccaaaca cataatctac
      601 taaatttttt atattttttt gttttaataa atctaaaaac tttatttttt taagaaattc
      661 tgtagctaat tcgctttctt catcacttat actctttctc ttcttaaaat taaacagttt
      721 atatttaaac atatcctcat ctgatggatc tagtattttg aattcattat ctctactcgc
      781 tattactatt ggtatcacac taagaacttc tggatactct tttaataaat ttttagtttc
      841 gttttctata tcttcttttc ctataagata gtttaagata tttaactgaa cctctatctt
      901 tctagtattt tccaaagctt tattccagtt aacataataa tcccagctag ctatagtacc
      961 ttttaaattt tcaagtaatt ccttaaatat ttcatcctta ctcttatttt tatgaatatt
     1021 cttaaccaat tccatttgat tccccacctc ttcataatta gtaattagca attcagttat
     1081 aaaacctctt ccattcccct tagaatttat gaatctttta gcatgtactc tttttatatt
     1141 aaaatctgaa tacaaatcat caaagaaagt atcttcttca tctaaaactt ttggatcaga
     1201 attacttaac atcaattttg tatctatttt atctagaact ttataaaatt tacttaactc
     1261 aatttgacta tcatcattaa aattaccttt gttataggaa ttaaatcctc ctatagttac
     1321 tggtctatat ggtggatcta gatacacaaa acaattttta tctattatat tttctagatt
     1381 taaataattc ttatttaata tttttacttt tagctctcct cgagaatctc ttttatttaa
     1441 aagcatggat aatttttcaa gttcattttt atcaaaaaaa ctaggatttt tatatcttcc
     1501 aaaaggtaca ttaaattcac ctcgagaatt ttctctatat aatccattaa aacatgtttt
     1561 atttaaaaat ataaaatatg aagcttgctt tatacaatct tcattttcta tatttttttc
     1621 atttgtaagt atattaaatc tatctctaat atcatagtac atcttttctc tatctgaaga
     1681 accttcttcg taagatatgt attgttcttt taaattagtt agttctgtta ttaactcttc
     1741 caaatcatct ctgactttaa tatataaatt aattaactta ctatttatat cattaattac
     1801 atacttgttg aaaatgtcct cttctaacaa atatagaaat agtgcacctg cacctacaaa
     1861 aggttctata taagtcatgg aactaaaatc acaacctgta ggcatttgtt ttcttagaat
     1921 atcaagtagc tgtgttttac ctccagccca ttttaaaatt ggtttcatgc aacacctctc
     1981 tcagttatat tgttatataa ttatataaaa taagattcta aaatacaagt actcatcaga
     2041 acactatatt tatatcaaat ctttccaaaa tctaagtatt attttatcct aacacttttc
     2101 aaaacctcta aataatatac aatattctct aatatttact tactaaaaat ttaaatctat
     2161 ctttaagtat aacctaaaac agattataag ttacgtagtt tttaatataa aatatacttc
     2221 tacaagtaaa gctttaaata tcaattactt atttcataat taatgactat gtaccctcaa
     2281 aaaaacctca ttttctatgg ttggggtacg gttggtggat ttcatcacca aaataaaaaa
     2341 tactagtcaa taaagactag tatttccaag tatttcatca ttcttttttc aaaattggtg
     2401 gagacgaggg gagtcgaacc cctgtccgca aatcttttcc ttgctgcatc tacatgctta
     2461 gccaacttca ctaatatctc acctcacata gcgccaagtg gcaggctcta tgcttagcca
     2521 gtcccaatta atctacttca ggtcgagaca cccctaaagt agttccctgc ataatgacgt
     2581 ccagtcttag tcggcaggag gactaagagg gacgagcagc aactaggctg ctatcgcgaa
     2641 attatcgtct gcgtttattt taaagttccc cagtttttac gtgacccaga gtaacacgac
     2701 atgcagcctc aagttccaaa cccacgtcga aacctttacg cccccttgag tagtttatag
     2761 tccagtagac ttttcgcaaa ctttatcacc atttttatta aatttttaat gtatatataa
     2821 tataatactt ttaagaataa aaatcaatgt tatgttctag ataataaaga attttattct
     2881 aaaaaataca gttttatcta gtttaatact tacctgtcat ttctctttct atacgtcttt
     2941 gtgcatcttt cttagccata tcttgacgtt tatcatatag ttttttacct tttgctaagg
     3001 caatctctac tttaacttta ccgtttttta gatacaaact aagtggtata agtgaatacc
     3061 cctttatagt agttgctcca ataagctttc ttatttcatg cttatgaagt aatagttttc
     3121 taactcttaa agaatcaaca ttgaatatat ttccttgctc atatggactt atatgaactt
     3181 gttttaaaaa tacttcgcta ttatctacag atgcaaatcc atcacttagg ttaactttgc
     3241 cttgtcttat tgattttact tctgttcctt ttaattcaat tccacattca taagtttctt
     3301 ctataaaata ttcatgtctt gctcttttgt ttgttgctaa tattttttta ccagccatat
     3361 aaatctcacc ttctttgcta gaaatttatt ccataaatat tagaaattta ctaaatattt
     3421 aatgttgcca aattatttga ctaacttgta tgataacata tttaggcatt ttagtcaata
     3481 tttcactgat atattaagtt agttaggcta tatataatta agtaatataa atgtatgaaa
     3541 atagctaaaa aactacttcg aatatactta atactaaact aactctaacc agtaatacta
     3601 atttataaat ttcaaaacaa aaatattaca tattataaat cttctatctt ctatcttcta
     3661 tcttctatct tctatcttct atcttctatc ttctatcttc tatcttctat cttctatctt
     3721 ctatcttcta tcttctaaat aattttaaca tgcccataaa atataatacc cacaaatgat
     3781 aaataatact caaaatgtct attgaaataa ctatacatcc ttaaataact taacttaaat
     3841 ctaaacattt caaaaacttc ttaaaaatat gtaaaaattt gatgataaag tagcgatttt
     3901 ttcaaaaaaa atgtaatata gagttatatc ttataatatt ttagagataa attttatcat
     3961 agtggggaga aatttgtatg gatttaagca aaaaagtaaa aattttagaa aatgcatcag
     4021 atggcaaaag cgaatttgag atattagaat ttgaaaaact tgagggagct tctagcccat
     4081 taatggcaat gggattatat tttgctagag aagctggttt gaaagctaga caaattaaga
     4141 taaaattaaa taattcatca ataaaaacag aagctggtgc attatactat tataaaggaa
     4201 atatatcttc tgaaactaag attggtggtg ttggaggtct ttttaaaaaa ggaatatcag
     4261 gagcacttac taatgaatca atgatgaaac ctgtatacaa aggtactgga gaagtttatt
     4321 tggaaccttc ttttagacat tatttattta tgagtcttga taatgattct ataattgttg
     4381 ataaaggatt attctattgt tgctctgata caatagaagt aaaagcattt acacaaaaga
     4441 acttctcatc tgctttactt ggtggtgaag gcttcttcca aatagaatta agtggtactg
     4501 gtgtaatcgt tctggaatgt gttgtacctc aaagtgaaat tgtagagtat gaattgaaaa
     4561 atggtgaaga attaaaggta gatggtaact ttgcaatagc aagaacatct ggtgttaatt
     4621 tttctgttac aaaatcagat aaatctttaa ttggttctgc tttaaatggt gaaggtttct
     4681 taaatacatt tactggtaat ggtacagttt ggctagctcc aactcaagta atgtatgaaa
     4741 aactaagttt tggagcaatg cctactaatg ataatatgaa taataaagtt tctaagcaaa
     4801 aatagttgtt ttataaatat ttattaaatc attattgatt ttataaagtc actataaatt
     4861 ttattagatt attattataa aatcagagtg tggaaatgtt tatgtgtatt ctttaaataa
     4921 aaatttccac attctgtaag gttattatac ttgatatata aaattcaatt taggaacata
     4981 gtctaacatt tataaacata ttaaggtaat gatttctctt ggtaattatt ctcatatctt
     5041 attctttgat tatatttatc ttattcctag cccttatgtc atattatatt tcttatctta
     5101 ttacttataa ttagcattaa cttatctaaa atcttgtatt tttttaatag taaagtttac
     5161 atctatatta aaaagtttac atctatatta atttcataaa acaatcaagg tagtcaagag
     5221 attcaacttt acttgatttt aaaaatttaa gtgaatttgt tcttatacac atctttttaa
     5281 aattatatct gtagaaaata tcatttagag ctataat
//
LOCUS       DAEHWO010000149         5115 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEHWO010000149 DAEHWO010000000
VERSION     DAEHWO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.152"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(541..2676)
                     /gene="rnr"
                     /locus_tag="KNP54_003849"
     CDS             complement(541..2676)
                     /gene="rnr"
                     /locus_tag="KNP54_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBF0894697.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3269..3883
                     /locus_tag="KNP54_003850"
     CDS             3269..3883
                     /locus_tag="KNP54_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBF0894698.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3901..4263
                     /locus_tag="KNP54_003851"
     CDS             3901..4263
                     /locus_tag="KNP54_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894699.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4369..4866
                     /locus_tag="KNP54_003852"
     CDS             4369..4866
                     /locus_tag="KNP54_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBF0894700.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1682 a          759 c          617 g         2057 t
ORIGIN      
        1 gaaaagttat cttaaataaa aaataagtgt atcttaaatt ttaaatgata cacttatttt
       61 tatattgaaa ttatattttt taatatctat tcttaattag gtatttttaa attatctgtt
      121 tacattaaat atttcttaat tacttatctt tcagctagct ttttctatta aatgtttctc
      181 aattacttat ttttcaatta gccacttata ttaagcattt cttaattact tatttttcaa
      241 ttagccactt atattaaaca tttcttaatt atttattttt cagttggctt tttctattaa
      301 atgtttctta attacttatc tttcagttag ctctttctat taaacatttc tcaattactt
      361 atttttcaat tagctacttt cattaaatat ttcttaatta tttatctttc agttaactat
      421 ttccattaga tatttctcaa ttacctattt ttatcattta ttttatagag tattgtgcac
      481 tatatattta tacatatcat aaatactaca acttgttatc tcttatttta gctgttttat
      541 ctactcctct attttttcaa ctatctcaaa gtcaatttct ttaaaatcta cattaacact
      601 ttcaaccttt atcttaacaa ggtctcctat cttatatgac ttcttagttc tttctcctaa
      661 aacactataa gaactctcat cataaatata gtaatcatca ttcatatttg caagtcttat
      721 caatccttct atggtattat ccaactcaac aaatattcca aatgaagtta cgctagatac
      781 aacaccctca aattcttgac caactttatc cttcatataa agagccttat agaaatcatg
      841 tacatctctt tcagctaact ctgcctttct ttctttctcg gatgattgaa cagatgcata
      901 atccactata gtagtaagct gttcttgtct ttttccactt attttattat ttaaagattc
      961 ttttattatt ctatgaattt gaaggtcagg atatcttctt attggtgaag taaagtgaca
     1021 gtagaattta gctgctaatc caaaatgtcc actacattct ggtgagtact tagcttgttt
     1081 taaagaacga agcattatag tactgatagc tccttcttct tttttgccct ttattttctc
     1141 tattatacct tgtaatgctt ttggatgtac ttcctcttta tcacctttta ttatatatcc
     1201 aaatgtagat ataaacttac tcaattcttc cattttttcc aaagatggtg tctcatgtat
     1261 tctatacaca aacggtattc ccatccagta aaaatgttcg gcaattgtct cattacttat
     1321 aagcataaat tcttctatta tcttattaga tattcttctt tcatatggct ttatatctac
     1381 aacttcgcct tttccattta gaattatctt tgcctctggg aaattgaagt ctatagctcc
     1441 tcttttttcc cttcttgaca taagaatcct agctaaaatt tcagcatttt taaaatcttc
     1501 aacaacatgt tcaaaagtct ttttaagttt ttcatcatcc ttttctaata tatcagatac
     1561 ttctgtataa gtcattctag cttttgaatt tattacagat tcacatattt catgtttaac
     1621 cacatttcct ttatggtcta tttccataaa tatagaaaga gttaatttat cttcaaatgg
     1681 atttaagcta catactccat ttgaaagagt ttttggcaac attggaatta ctttatctac
     1741 taaataaact gatgtagctc tttttaaggc ttccttgtca agtttatttt tctctcttac
     1801 ataatgtgta acatcagcta tgtgaactcc tagtttgaag tttccattag gtaatacttc
     1861 tattgatatg gcatcatcta agtcttttgc gtcatctcca tctatagtaa atatgtttaa
     1921 atctcttaaa tctcttcttc tttttatctc ttcttgagga atctcaacag ctacagcttc
     1981 tgcttcttgc aatactttct ttggaaattc ttctggaaga ccatgttctc ttattataga
     2041 atctatttct acgcctcttt cacctttttg acctagtatc tctataattt tgccttctgg
     2101 ttttctatcc tcttgtggcc atactgtaat ttcacatact accttatcat tatctactgc
     2161 tccactaaaa tgttttttag gtatatatat atctttagta aatttcttgt tgtctggtgt
     2221 tacaaatcca aaagttttac ttgattggaa agtacctact attctagtta tttctctctt
     2281 tattactttt actattcttc cttctgctct cttttcttca gttgcaggta ctactatttc
     2341 tgccataact ctatcattat gcatagcacc atttatattg tcacttgaga taaataaatc
     2401 ctgtgtatat tcaacatcag attctacaaa tccaaaaccc tttttgtgtg atacaaattt
     2461 tccaacaaag tatcccattt gattgggaga tactattttt ccttttttag taaagcagat
     2521 ataaccatct tcttctaatt catttaaaaa attataaaac attggcattt ctgatgaatg
     2581 tatatcaaat atttctgcta attcttcttt ttttagagga ttatatgcac tttcatttat
     2641 taatcctagc aaactttctt taagtcctgg tatcattttt ccctcctgtt ttacttttca
     2701 ttatattatt atttatattg tcttttatat ttcttcagac aaaacatttt ttaattatca
     2761 cataattttc tatattttct tattattata agttaaaatt acttatttat atttttgatt
     2821 taatgtaagc tttgtcatac taacttcaaa caaattatga tgttttataa attatttgta
     2881 aatatcatta taattactta agttattctt tatcataatt gcttaaatta ctctttatca
     2941 cctaattata caccatcaaa taggattggt aaaatattca tctcatataa gtattactat
     3001 ataataattt attctattag tatactcaaa tcatgtaaaa tttatataac tcaattaatt
     3061 ttttaaatac aactttataa tataaaactt ataataaaag taaatttata tgttaaatga
     3121 ggttgatttt ttattatttt ttatttatgc tagtactaaa gacttgcaaa cgttttttga
     3181 caagtcttta ttttgtctaa attaaacaaa cttttttaca aataaataca taaaatttaa
     3241 actaatctat ttattggagg agataaaatt ggaagaagta attgcaaaaa ttattactat
     3301 agaaaatgga ttcaaagaaa ttgaaaacat tgctaaaaaa attgtaaaaa ataatgactc
     3361 aaaaaagtgt tattatctat caatctactt atataggtca gaatattatc aagtaagaga
     3421 attggctgtg tttatacttg gttttatatc agtaactatt tctgaagctt tgttattttt
     3481 aaaagataat gtgagtaaag atgaaaactg gagagtacaa gaaatactag ctaaatcatt
     3541 tgattattat tgcagtgaag taggatatga aaaggctctt cctgttataa aagaatggct
     3601 taattctgat agtccaaaca taaaaagggc tgtgacagaa ggtcttcgaa tttggactag
     3661 tagagactat tttaaatcta atcctgacgt tgctatatca ctactttcta gtttaaaaga
     3721 agatgatagt gaatacttga gaaagtctgt aggtaatgct cttagagata taagtaaaaa
     3781 atatccagat ttagtaaaaa aagaattaga ttcatgggat atatcaaata aaaaagttga
     3841 gtttgtatat aagcttgctt caaaatgtat cttggcaaag taaaatggag gtgaacttat
     3901 ttgaaacttc gtgatgagta tacttgccca ttagaactaa cacatgatat gataaaaggc
     3961 aaatggaaat ctattatatt atggagatta cgcataggac caacttcctt atcaaaactt
     4021 gaaaaggaaa tcaatggtat taatcaaaag atgttacttg aacaacttaa agaattaatt
     4081 gaatttggtc ttgtagataa aaagacatat gaaggttacc cacttaaagt tgaatactca
     4141 cttacaccta ttcgagggaa acaaatattg gatgctttgg ctataatgca agatatagga
     4201 attagcttta tgttggataa tggtatggaa gatattctta aggaaaaagg tgttttaaaa
     4261 taaatagata cccacaaaaa agtaagtaat ttaccattat tttcaactgg tatataatta
     4321 aattatagat atattctatt aatttattat aataggaggt aaattattat gaaagtaact
     4381 agtacaggta tagtaaatgg tgttatagaa gataaatacg gtaaaagagg aactcagttc
     4441 aatgaaggtg gtatgcctac atattcacta cctctaaagt ttgaagatgc tccaaagaat
     4501 acagtatcct ttgctgtatt tttagaagat aaagactctg ttcctgtatg tgggtttgca
     4561 tggatacatt ggttagctgt aaatataaca aaagatgagt taaatgaaaa tgaaagtgta
     4621 acagctactg attttgtaca agggactact agttggcatg gcaaactagg aggtcttgac
     4681 agattagagg ccagtgtata tggtggaatg gctcctccag acagacctca tgtctatgaa
     4741 atacatgtat ttgcacttga tactatcctt gaccttgaaa aaggattcta tatgaatgaa
     4801 tttttcaaag ctattgaagg gcatgtttta gatacattta cactaaaagg aagttattct
     4861 aattaattag gttgactata gctaatcatt aattaaatgc tacatttaat tgatgattag
     4921 cttaattgtt attagaatat tttctgcact ttatcttaat atatatttta gttgactggt
     4981 attttaattt ctattagatt attatcaatt tatataaatt gattttagct taaaacttac
     5041 ttatctattt cagtttctat tagaattatt attagactca ttaaaataaa agcactaata
     5101 taactaataa tatat
//
LOCUS       DAEHWO010000150         4970 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEHWO010000150 DAEHWO010000000
VERSION     DAEHWO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4970
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.153"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            9..812
                     /locus_tag="KNP54_003853"
     CDS             9..812
                     /locus_tag="KNP54_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894701.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESALKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            824..1954
                     /locus_tag="KNP54_003854"
     CDS             824..1954
                     /locus_tag="KNP54_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0894702.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            1958..3367
                     /locus_tag="KNP54_003855"
     CDS             1958..3367
                     /locus_tag="KNP54_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBF0894703.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYIIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            3578..4087
                     /locus_tag="KNP54_003856"
     CDS             3578..4087
                     /locus_tag="KNP54_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBF0894704.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
BASE COUNT         2071 a          426 c          856 g         1617 t
ORIGIN      
        1 ggcacattat ggaaaaattg agagttattg aaatgataaa aaataatccc aatattatag
       61 ctacaataga taatccaact gatgaaatga aattgttagc tattaaagaa aatgggcttg
      121 tactagaata tataaataat ccaaccagag agatgcaaga actagcaata gataataata
      181 ttagagcaat taaatttata gataatccaa cagaagatat gatgataaaa gcagtaaatg
      241 agggatggag tatactggat tatatcaaaa acccaactga taaagttatt gaaatggcta
      301 taaatcaagc aggatgggca attaaatatg ctaaaaatcc aagtgaagaa ttacaactgt
      361 tagcagtaag aaaaaattat gattcgataa agtttataaa acaaccttat gaaagtgtac
      421 aagaggaggc agtgagaata agttatgatg ccttgagata tatagattca cctagttata
      481 atgcagaact tatagctata aaaaataatg aagcagctat tagctttata actgatttag
      541 ataaaaataa aatgttggaa tttttaaaag tgaatatttt agtgattaag tacattctga
      601 aaaaagtatc taaagatgaa ttagagagtg cattaaaaga agtattatcc aaagaagatg
      661 ttgaggaaaa gtatattaga gattttttga attgtagtgt tatagataga aatagcgaaa
      721 gtataccaat agataaaatt atgtttattt ataaatatgg aagtaagaca gcaaaaaaaa
      781 tagctgtaga tgagaaatta aagattatgt aggagagaga aaaatgaatt ttatagacac
      841 attaaaaagc gttgacttaa tattatccac tggagaagta cctttaatag taggtgaaag
      901 tggaatagga aaaacagctt tagcaaataa gcttgccaaa gaaaatgatt ggagtttaat
      961 tgttattgat ggaaacttac ttaaagaggg tgaaataggt ggtcttccaa ctatagaatc
     1021 ttatgtagga gttaattcta atggatataa gactgaaaag aaaacaacag tgtatgctgt
     1081 tcataacaaa ttaagagaaa ttgatgaaga gatatctaaa agtaagacag ttcttttatt
     1141 tatagatgag ataaatcgtt gtgagcatac agtacagcaa gaacttatga atttaatttt
     1201 aaatagagaa attaatggat ataaactgca tgatgatgta aagattttag cagcaatgaa
     1261 tccatcaagt aaatatggtt cagattttga ttatcaagtg gtagatatgg atgcagccca
     1321 agaaaatagg tttgtttggt taaatatgga gagtgaccat acacaatgga taaaatgggc
     1381 aatagatgag ggtattgaaa gaaaagttat cgagtttatt tccacttttc cagaatatct
     1441 gcataaaata aatgaagatg atgtaagagc cactcctaga agttatgaga gagtatctaa
     1501 aatttataaa gtttataaag aaaaaaataa ttctattcct agagcagtat ttttaaatgt
     1561 tgtaaagggt aatgtaggta aagttattgc agaagaattt ataagtttta ttgaatcaaa
     1621 ctctgaacca ttaatatcct atgaagatgt ttttttagga gaatctattg atgagtctat
     1681 tgtagaaaga gtaaaaaatg agagtcatac aagactttat ctatcagcta tgaacattct
     1741 aaaagactta gaattaaata ttaagaatga taaatatgaa tcaaaccact atattaatag
     1801 atttattgaa tttttaaaaa tgtatcctgt agatttaatg ataggtatta tgaaggatat
     1861 tagaaacagt tatattgaag tatataaaaa agctatagaa aatgaagagt ttgtaaaatc
     1921 atattttgaa tcttatagtt taataagggg ataatgtatg gaaaattatt ttgataaaca
     1981 agcaaaagag ctttataata aagcaagtga aattataaat actcattcta tgctaaaggc
     2041 aaatcgtgct aatgagaaat ttgatataga tataccacaa gattttaagt atgagttttt
     2101 tagtcttgta gataaagtga atttaagtct tatggaagaa gaagataatt tttatggata
     2161 ttttttgttt cagatgtcaa gagaaataag atttgatata agtagtccta caggtgtgaa
     2221 ttttaaggga gctaaatata ttatatattt taatccaata atctttttaa cgcttgacat
     2281 aaagcaaatg gagactacaa ttaaacatga aattcatcat atattatcta tgcatttgat
     2341 gagagcaaag gagttaaaag gaaagtatag tacattagca attaatatgg caatggatat
     2401 agtagtaaat aaatttctaa acaatttacc accatatgca actaccttag agtgggtaaa
     2461 tttaaaatat tccttaaaac ttgaaccata tgaacctttt gaatattatg tagaaaagat
     2521 tcagactgaa ttagatttga tggaagtgga tgaagatggt gaggaagatg atagtgataa
     2581 atatggagat atagaaattg attatagccc cgaaagaact catgatatat gggatgaatc
     2641 caatgagata gatgaaaata cccttagaga atttactgaa aaatttatta acagttctca
     2701 aaaaggtaaa gttcctgctt atttagaaag tatgatatca tcacttaaaa atagtaaggg
     2761 tgaattgcca tggaatttat atcttaatag aataatggga acagttgaaa ataataaaaa
     2821 gaagactata acaagaagaa atagaagaca accaaatcgt ttagatttga ggggagaact
     2881 tagaagtcat aagtcagaaa tagcagttgc acttgatgta agtggaagta ttagtgatga
     2941 agagtttaaa caagctatta aagaagttct tagtatagtg aaaaactata atcatgaaat
     3001 tacaattata gaatgtgata atgaaattag acgtgtatat aaagtgagaa ctgaaaaaga
     3061 tataaaagat agaattagga taggtggagg tactagattt tctccagtct ttgagtatgc
     3121 taataataaa aagattaatt tgttagtcta ctttactgat ggtaaaggtg aaaataaact
     3181 acaagtaata cctagagggt acaaaatttt atgggttatt tctggaagag gagataaaat
     3241 ttcattaaaa gaaccttatg gagcagttaa aaaacttact aaggttaaaa caaatgatga
     3301 aatattagaa ataaatgatg taagaaatga tgggtactca atgaatagcc aagcaccaat
     3361 tttataggta ttcacaggag ataagctgta ttaatttatt ttgatatgct tgttataaaa
     3421 atctaaaaaa tacattaatc aatggttaat gtatttttta attttaataa tataagtttt
     3481 acttacattt aagtctcaaa atgtgttaaa atataatata tagcagatag ttttggcaag
     3541 gtggatttag ttgtcaaaac tatttttttt attaaggatg gtgatgtttt tgtttaagat
     3601 tgatgattat ataatgtatg gtatgacagg agtctgcaaa gtcatggata taacaaatga
     3661 acgatttaca aatggaataa aaaaagagta ttatgtattg agtcctattt attctaataa
     3721 tacagtaata aaaattcctg tagataatga aaaagtacca atgagaaagt tactttctaa
     3781 aattaatgtg ctttcattaa taaatgatat tcctaatatg gatacatcat ggatagataa
     3841 tgaaaaattg agaagtgagc aatttaaaaa aatactcaga ggtggtaaat gtgaagagtt
     3901 aataaaatta gtaagaagta tagataataa cagagagtat gtaaaatcta ttggtaaaaa
     3961 aacacatcaa gcagatgata atataatgaa agaagctgaa aggttattaa atgaagaatt
     4021 tgcaactatt ttagatattt ctcctaatga agttagttca tatatttcaa gtcatatacc
     4081 tcaataaagt gttttagtat cctttattta atctatttta agtattattt atgtatgctg
     4141 gttttggtaa aataaaatat ataattaaat tatataaaaa ataataatga ttgtattgaa
     4201 gaattacaga atagtgcgga gagcctactc ctttaggtgt gagatggata tcacttaaag
     4261 atttaaattg ttattgtaga tgtttttaat ataaaacaag attaataagt gtattgtaag
     4321 ctttaagtga aattgatact ataatgagtt acttagattt taaaatatat aatattataa
     4381 aaaatccttt taggttttga atgaataaga tggatactat gttgaataga atccatctta
     4441 tttaagtttt atttatgttg tttatttgta agcattattt ttgtacatga aaacacagtg
     4501 taaaaatatg cttagaatta tgaagtttta ttaaaaagat attcgacaaa ataagactaa
     4561 aaatattctt aaacttataa ctaagataaa tattgtatat ttatagtgta gcctgaaaaa
     4621 ttgtggatgt acgaaattta tttagtattt tattgaaaca aagtagaaga agtactatag
     4681 tttatctttg aatagattgt tattttttag tgaaaaagtt attaggttaa tacataaata
     4741 taatagctta taaatagttt aagcatgtta aaaaagtagt tattagagat atatagttac
     4801 attgcttata agatacttaa aatgatagca ttcacttata ttcagaagat taagataaaa
     4861 aatcattttt atatagtaaa gcatacctaa atttagaaaa taattgaatt tataaaatta
     4921 attaaataca taaaaaagta ttcaatcaac ttaacaaatt ttcttaaatt
//
LOCUS       DAEHWO010000151         4932 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEHWO010000151 DAEHWO010000000
VERSION     DAEHWO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.154"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(567..1208)
                     /locus_tag="KNP54_003857"
     CDS             complement(567..1208)
                     /locus_tag="KNP54_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBF0894705.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            complement(1451..2254)
                     /locus_tag="KNP54_003858"
     CDS             complement(1451..2254)
                     /locus_tag="KNP54_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBF0894706.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            complement(2410..3585)
                     /gene="thiI"
                     /locus_tag="KNP54_003859"
     CDS             complement(2410..3585)
                     /gene="thiI"
                     /locus_tag="KNP54_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBF0894707.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEESTILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            complement(3631..4782)
                     /locus_tag="KNP54_003860"
     CDS             complement(3631..4782)
                     /locus_tag="KNP54_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBF0894708.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
BASE COUNT         1534 a          931 c          473 g         1994 t
ORIGIN      
        1 ttataaaaaa gttactattt attgaaaatt tagatatttt tctaaaaatt atctatgtta
       61 atagttaaat ttatgaacat tttttgtttt tatgttagga tatttcttag aaatgaaata
      121 cttcttaatt tgatttgata tgtatatttt tatagctatt ttattataaa aaaaaagaac
      181 ccttttataa ctaagggtta ctttttttct ctattttttc ttattatatc actatttttt
      241 ccctatttca atattttgac attttttcca ttatactgaa aagatatctt aaatttttaa
      301 cttggataaa ttttaaagca tatacttaaa attaacatac ttgttttcta ttttattaca
      361 cttaatcctt atttttatca ttctacaaaa caaaaataaa aaagaataag ataataaata
      421 aaatacttat caccttattc tttatttaat tattttacaa cgaaaaatct aaactacttt
      481 ttaaatagct tcctcttcca tcaatttatt tgtatattac tgatttaatt cttcaagtaa
      541 ctgattggtt cttgcaatac tttatcctaa actctggaaa ctttgtaaac tacctctcta
      601 gcatttggta aatttccatc tggaatacct acagcaatac caaatggtac agaataccct
      661 tctggtatat caagtagttc tctgtatttt ttatttgtat caaacttcat ctttattgac
      721 tctgattctt ttacatcttc tttatccaat acactcacaa gaccttcaat atccccttgt
      781 tcaacaggtg taaataaacc tctaaccatt cctattatac aacttccaag ccctagtgct
      841 tgtgcagctg ttgttatatt ccctgtaagt attcctatat catatggagc ccatgaacta
      901 ctttcatcat aagaaataaa taaaacggtt ggagcaccat aaaataactt aaagttttta
      961 tttatctcaa cattactcac ctcatgaatc ctagataaag tatcatcact aatctctttt
     1021 aaaagtttct ggtcttgcac aacagttatg tgccaaggct gtttattaca tcctgaaggt
     1081 gctgcaaatg cacagtgtaa taatgtgttt acttgctcat cactaatttg ttctgtcgta
     1141 aattttcgta tacttctacg actttgtatt aaatttattg tttggttgtc ttgaaaatta
     1201 ttattcatat ctattcccct ttttatgtat ttcttagtac aaatactaaa tcttcagaaa
     1261 attaatctta taattaaatt tctttacaat attattataa ttatttttag cttgtatgtg
     1321 aagacttaaa aatataaaca cttttaatat atctcaatta tatatataaa tgaaaatctg
     1381 gtattcgtca tctatagaaa ctgctctttt ctatagttta atcaatacca gattaataaa
     1441 acatgatata ttaatttaaa ggaccccatc cctctttaga atgaatctct gtttttacag
     1501 acttaacact atctgtgtca acatcccatg acctacctgc aacagaaata ccatttttac
     1561 ctttatacca tctaccttca tcataatcgt aaactaggga agtataccaa ttacccccag
     1621 tcttattatt tgcaaataca actacagtag catcagattt agtaggatta tatgcatatg
     1681 gttgtatata tagtgtatcc ttacttaatc catattttgc cttaaattca tctggaattg
     1741 taggccaccc atttttatat ttattgtcta ataaatattt tctaaaatca tcattaccct
     1801 ttgaggctcc tggtattata gaagggtctt gtgcaaatga tgcaatcaaa tctttcatac
     1861 tttgatgtat atccctagcc atttcaacac catctggatg ttttgtacaa gtaacataca
     1921 cttttgcaat gctttctatt ccagttattc catcataacc atcatcaaac gttgctgaat
     1981 atattccacc tgacttacac tttggttctg tttcaaagta cttaccatct ttgttttcta
     2041 atacctcttt catgacttca ttcttgcctt tacttgattc ctcagccatt gcaataacaa
     2101 tttgagtctt tatattttct ctattagaaa gacatgtaac tgctttactt ttttctatat
     2161 ttctaaacaa tgctggaaca gctactataa ctaaaatgcc tattatagat ataactacta
     2221 acaattcaat tagtgtaaaa ccctttttat tcataataat cattcccatt aaataaaatt
     2281 atagtactta tttttaaata ctacatatta ataaattgtc tacataaatc ctttcaacag
     2341 aactactaat atacttacag aactactaat atactcaata ttcaatttag taattaaata
     2401 acttgtatgc taaaactcaa tatcctctac ctctattttg tcaatagcat cctgtactaa
     2461 tttttcaatg tcaagtgctg tttcagattt ttctattttc tctaatctag gtttagtgac
     2521 gggctttcta ggagaaaata cactacaaca atcttcttca ggcactatag atgtttcaaa
     2581 agtccctatt tttttggcta tatcaactat atctgattta tccattgcta taagtggtct
     2641 aaacactggt aagtctacaa cggcattagt acaagtaagt ccttgtatag tttgagatgc
     2701 aacctgccca atactttcac ctgtaattaa agcatcacaa tgtctttttt cagaaagtct
     2761 ctgcgctatc ctcatcataa atcttcttga aagaatagta gattcttctt cattacaatt
     2821 ctcgccaatt gctttttgta tttctaagat attaacttta tgaagcctta ctctaccaca
     2881 gtattttgcc agtattttag ctaaatcctt aactttttcc tgtgaccttt cacttgtaaa
     2941 tggataacta tgaaagtgaa ctgcctctac ttccatacct ctttttgcaa ccatccatgt
     3001 agctactggg ctatctatac ctcctgataa aagagacata gctctaccat tcgttccaag
     3061 tggcaatcca ccatatccag gtatagtatc actatagacc atagtatgaa attctctgta
     3121 ttcgcacttt attttaactt ctggatttct tacatcaaca ttaatcctat ctcctacctt
     3181 tgataataag tatccaccta tatccatact catttcttga gaagtcaatc cgaaagactt
     3241 atctcctctt cttgactcta ccttaaaagt tttatatcca gcctctattt tttcttctaa
     3301 catttttaaa gctatttctt ttaatgtatc ataatctttt ttagctctta ctccagggca
     3361 cacacccact atcccaaata cttttctaac ttcttcaatt acttcttcat aatcatagtc
     3421 ttctaaatca acatatattc ttccatactc tttatataca ttaaatcttc caattggttt
     3481 taacatattt cttatatttc ttataagcct attctcaaat atatatctat tctttccttt
     3541 tactccaatt tctccatact ttactattaa tatattatac accatttcac ctcttaaact
     3601 aatttattat cactatttat acagtattct ttattttctt ttcattattg accttaagtc
     3661 acaaattgat tctttcaaaa ctttcacagc ttctaacatt tcttcttctg tattcatatc
     3721 agataaacta aatcttattg ttccatttat ttcttcattt gtaagaccta tagcatttaa
     3781 tacgtaacta cctttctttt tagaagaaca tgcagagcca gttgatacat aaataccttt
     3841 ttgctctaag taatgaagta aaacttctcc ttttgtccct ctaaatgata catttaatat
     3901 atgacatact ccgtcttctg gagaattgat ttttatatct tctatattat caattatttc
     3961 attttttaat atatttttta agttatctac tttcgaaata acagcatcta aatctttgtt
     4021 tagtattcta acagcttctc caagaccata tattccaggt acattttctg ttcccgacct
     4081 aattccaatt tcctgaccac cacctgttaa cataggctta aggcgattat tttcttttat
     4141 atacataaat ccaattccct ttggaccatg aaatttatgt gcacttacac tcataaaatc
     4201 tatattgtat ttagatggtc taaagttaat ttttccatat gactgaatag catcaacatg
     4261 gaaataaatt ttttctttta aacccttcaa atactttcca acttcaccta ttggctgtat
     4321 agttcctatt tcattgttaa catgcatcat gcttactaag catgtagttg actttatcgc
     4381 attttttaaa tcctctatat ttattttccc atcttttccg acctctaaat aagttacttc
     4441 aaaaccatct tcttctaaat cttttaatgt atttaaaaca gaaggatgtt ctatgttagt
     4501 agatattatg tgattttttc tttttttatt taaactagta atacctctta ttatagtatt
     4561 attacactct gtaccacctg atgtaaaata aatctccttt tctttcgctc ctagagattt
     4621 agctatatct tgtcttactt cttttatagc tttttcaact tctacacctt ttctatggac
     4681 agaagaagga tttccatatt ccgtattaag tgcataaacc attttatcta taacttcttg
     4741 ataaggtttt gtagttgcgc tattgtctaa gtatatttcc aacttaatta cacctacctt
     4801 tatttaaaat cttcaactct aactattata ccactaatta tagtattttt tttgttaatc
     4861 tttattaaaa agacaatctt aaattataaa atattatttc atgaaaagct agttttttca
     4921 ctttattaca aa
//
LOCUS       DAEHWO010000152         4801 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEHWO010000152 DAEHWO010000000
VERSION     DAEHWO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.155"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(205..1008)
                     /gene="proC"
                     /locus_tag="KNP54_003861"
     CDS             complement(205..1008)
                     /gene="proC"
                     /locus_tag="KNP54_003861"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBF0894709.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEKFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(1333..3702)
                     /locus_tag="KNP54_003862"
     CDS             complement(1333..3702)
                     /locus_tag="KNP54_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBF0894710.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(3707..4615)
                     /locus_tag="KNP54_003863"
     CDS             complement(3707..4615)
                     /locus_tag="KNP54_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBF0894711.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
BASE COUNT         1425 a          913 c          518 g         1945 t
ORIGIN      
        1 ttcacaatga tatatctcaa atatagttaa aaatatatct atttaattat taatatttaa
       61 gtaataaatt atcactcaat cattaaattc ctttttatag taaattactc ttattttact
      121 tataccaaat acatttatgt atagatataa ataagcacta aaaaaacaat tcaagaaacc
      181 atatagtaaa cttaattaca tctgttattt gctcatatct ttagacttat ctatacaagc
      241 aacaatagat tttataactg ctgctctaaa gccttcttct tctaatacct taacagcttc
      301 tatagtagtt cctgctggag aacaaaccat atcttttaat tcacctggat gttttccagt
      361 ttcaagaacc atcttagctg accccattac tgcttgagat gcaaatttat aagcttgttg
      421 tcttggcatt ccagctaata ctgctgcatc tgccatagct tctataaaca taaatacata
      481 tgcaggagaa gaaccactaa tacctgtaac tgtatccatt aaatattctg atactatttc
      541 tgcctcacca aaagattcaa acagagcctt aatcatattt aactcttcat ctgttacatt
      601 actattttta caaagagctg acattccttc gccaacaagg gctggagtat taggcattac
      661 tcttactatt tttttatctg aacctataaa actttccaga ctttctatag ttttacctgc
      721 tgctatagat actattattt tatttgcatc tattaattct ttaagtggag ttaaagcctt
      781 ttcgcatata ttaggtttaa gtgctactat taccacatca gaatttgtaa cagctacctt
      841 tgaatcagtt gtagtattta ctccaaattt ttcttttact ttatctaagg caacttggct
      901 taaatctgat acagttatat cttctgcctt tactaatcct gactgtacta tgccacctat
      961 cattgcactt cccatattcc ctgaaccaat aaatcctaaa gttttcatat caaatctcct
     1021 tttttctatt agttttattt taaagtagct aaattgactt tattttaact gcttaaaatt
     1081 atcttatttt tataaaatat aaccttatta taactataat aaattattct tttgtatgta
     1141 ttacttacta atatgtgtat gatttactaa atataaattt aacgattttt tcattaaact
     1201 taacgagcta acttcctatt tagaaagtta gctcataatt aatctaaaat tttaaaaatg
     1261 gaatcaaacc atttatactt tattatatca gttacgattt tatatagtaa gaagttttat
     1321 ttacaagcaa acctagaatg tttgctcagt tcttcctatt atctcatctt gtagtgttct
     1381 acttaaatta ttgaaatggt cactatatcc tgcaactcta actattaagt ctttataatc
     1441 ctgaggattc ttttgagcct ctaacagtac atttttatca aatacattaa attgtatatg
     1501 atgaccatcc atattaaagt atgctcttac tagattagcc atattatcta accctttttc
     1561 tccttgaact actgatggtg caaatctttg atttaataat gttccaccag tttttatgtg
     1621 gtccatctta gcacaagatt ttataactgc tgtaggtcca ttagtatctc cacctttttc
     1681 aggtgaaatt ccctctgaaa ctggttttgc acaaagtcta ccatttggac ttgctcccat
     1741 aatttctcca aagtatatat gacaagttgt tggtaacata tctactctgt attctccacc
     1801 acaaacagtt ggtctaccag ttacctcatt gtaatatgca ttgaatatct cttgcattat
     1861 ttcatcagca taatcatcat catttccata tttaggagtc ttatttgaaa ctaaattaag
     1921 tatagcttca tatccttcaa aattagcatc aagtgcttta agcaatgtat ccatatcgaa
     1981 ttttttctta tcaaatacat tatattttat tgctgttaaa ctatctgtta tagttcctat
     2041 accaacacct tgtatatatc tagtgttgta tcttgctcca cctctttggt aatccttgcc
     2101 tttttctata caatcatcaa ctattgtaga cataagtgga caaggcatgt gttttgcaca
     2161 tatattttct atcacagcat ttccttctat ttttatgtca atcatataat gtaattgctt
     2221 tttaaatgct tcaaatagtt cctcataaga ttggaaattt ctagggtctc cagtttcaat
     2281 acctatttgt tttttactaa ttgggtcata tccattattt aatgttaatt caagtatttt
     2341 tggaatgttc atatatccag ttagaacata tgcttcttta ccaaaacatc cagtttcaac
     2401 acaaccactg gttccaccaa gtcttgcatc ttctatagtt tttccagctt ccataagctc
     2461 ttgaactatt gcttcagtat tataaaatgc tggttgaccc catccttttc ttgatatttc
     2521 acaagctctc tttaagaatt tttgaggagt ctttttactt atttgaacat ttgaactagg
     2581 ttgtatcaat ttcatttcat ccataacatc aagtattata taactaactt cattaacacc
     2641 atcttgacca tctggattta ttccaccagt gtttatattt gcaaaatctg tatatgtgct
     2701 actttctttt aatgttatac caacttttgg tggtgctggc tgattgttaa atttaaccca
     2761 taaacattca agtaattctt gtgctctatc tctatctagt attccatttt ctacatctct
     2821 ttcatagaaa ggatttagat gttggtcaag tcttcctgga gtaaaagcat cccatatatt
     2881 aagttcagta gtaaccccta tatgaacaaa ccaatacatt tgtatagctt gatgataagt
     2941 ttctggtttg tgagctggta caacatcaca agtttcagca attagtaata aatctttttt
     3001 cttagcttca tctgtttctt cttctgccat ttgtcttgct ttctcagcat atcttttacc
     3061 taatataacc attgcatcac aagctattgc catagcttct aaatctgctt ttttattata
     3121 tgcatctaaa tcattaagaa aatctagctc ttttaatctt gcttctatgt ctttctttaa
     3181 atctaaaaat ccttttttat atattgtatc tccacaaact gtatgtcctg gagctctttg
     3241 ttccataaac tctgtaaaca tacctgcttc atatgctgct aaccactcag gtgtcattgc
     3301 atttattatc ttatctcttg tttgtctctt tttccaaaaa ggaattattt cttctttatg
     3361 tatttttcta gcttcttctg atacgctaaa atttattata tctctattgt gcattacttc
     3421 taaatcttcc attgtatgac aacaaatttc tggatatgtt ggtgctccat taggagaatc
     3481 acctttttca cctactatta attctccatc atttatgcta agagttctat tctcaatata
     3541 atgcttaaat gataaagcac gaagtacagg aatctctaca cttccctcat attttttata
     3601 agcttctgtc ataagtactg ctctttcaat agatatgtgt ggttctgcat taatactttc
     3661 ttctcttaat tttttagttc tctcaaaagt tcctcttgcc attttattac cctccaatct
     3721 tagtattgaa attacttgct tcaaacagtc tttttatttc ctctaatttt tcttctgatg
     3781 gtctttgtag ttcttctcct tcatactttt tataaatttt atcatacttg tgtttaccaa
     3841 tattatgata tggaagaaga cttactgctt gtatattcaa aggctttaaa aactctatca
     3901 tttttttaac ctctaaattt tcatcatcta catttactcc tacaattaat ggtattctta
     3961 tatttatgtt agcccctaat tcacttaaaa tcttaacatt tttcagtatt aagtcatttg
     4021 attttcctgt aaattttatg tgcttatctt catcaataag cttaatatca tataaaaaca
     4081 aatctgcaca tttagcaact ctttcataat tttctgactt tgcatagcca catgtatcaa
     4141 ttgctacatg gattcccttt gatttgcaca tgtttattac tccacaaatg aagtccatat
     4201 cttgagccat tacttctcca cctgatagag ttactccacc acctgattct tcatagaaaa
     4261 ttctatcctt ctctatctct ttaaccaaat ctcttacaga atactcttga ccaacaatct
     4321 ctcttgcatt gtttacacaa tagtctaagc aagtttcaca aaactcacac ttatcttggt
     4381 ctaagcatat ttttgtttca cctttgtaaa ttgccttatg agggcatata tttatacatg
     4441 cttcacattt tgaacatctt tcttcattat acaaaacttg ttttgtatat gtttgactct
     4501 ctggattatg acaccaaaca cattcaagtg gacacccttt aaaaaatact gtacttctta
     4561 tccctggtcc atcatgtatg ctacattttt gtaagtttat aactaatgga ttcatgattt
     4621 ttcaccccta aataatatcc attccatttt ttcattttta tgcaattcat cttcatagaa
     4681 tatacctatg aaaagcattt ctacaattac ataatactat attcgttatt attttgtcta
     4741 tatattttta gtaatattaa aaaattttat tttattatga tatttatatt gtttttgtaa
     4801 a
//
LOCUS       DAEHWO010000153         4654 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEHWO010000153 DAEHWO010000000
VERSION     DAEHWO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.156"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            768..1430
                     /locus_tag="KNP54_003864"
     CDS             768..1430
                     /locus_tag="KNP54_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894712.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            1439..3946
                     /locus_tag="KNP54_003865"
     CDS             1439..3946
                     /locus_tag="KNP54_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894713.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQVMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            4277..4621
                     /locus_tag="KNP54_003866"
     CDS             4277..4621
                     /locus_tag="KNP54_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894714.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKHLTVKGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
BASE COUNT         2057 a          414 c          692 g         1491 t
ORIGIN      
        1 ataatcgtta ttaaagacca aaaatcccac cttagaagtt tgtatcatat gaaaccttta
       61 tagattatga aagcaataat atagtgtatg atatataaaa taagttataa aagtattttt
      121 ttagatattc aaaaagacat tgtaagttat attaataata tgggtatcaa cgaattttgg
      181 atataatgag tttttcaact taaagttatg taataatgaa tgtaaagaat atttaatgaa
      241 atcattttgt tggttatgtc tagctgaata caataatctt ttagataaag attttatatt
      301 tgaagatagg tgtgaaaaaa ttaagaagat attaacatca gcagtttaga ggcaaagcat
      361 gtaaagtaaa gtctgggtaa ctaaaagtag taatttagat tgtaactatt gttataaata
      421 tgaaaatgag gaaacaggaa atataagtta ggatgtagaa aataggttac taaataaaaa
      481 gcttaattat ataatcaaag aaataggtat atactgtaca atttcatggt gaagaacttt
      541 tcctaaataa aaaggttggt aaaagagata taagaaataa aattcaatta taagatatgg
      601 tatgataact aaaggcacta tatggagtga ataggcggaa gaattttttg aaaattataa
      661 aaatagtttc tgttgctaca tatcaataag tatagataga gattgcaaaa tccatagcaa
      721 aaatcgaatt tataagtgta aataacatgt aagacaagga gtaaattatg agtattttag
      781 agataaaaaa cctaaataaa atatatggta aatcggaaac agaggtgaaa gcgttaagtc
      841 aaataaatct aaaaataaat agtggagaat ttgttgtgat agtaggtaaa agtggaagtg
      901 ggaaaagtac tttactacac ataatggcag gacttgaaac tccaacaaat ggtgatgtga
      961 ttattgataa tataaatata tcatctcttg atgaaaagaa aagatctgca ttacgtaaag
     1021 aaaagttggg attaatattt caatcatata atttgattcc agttttaact gttgaagaaa
     1081 atataaaact accaactata aatataaaaa ataaagatga agcttatatt aatgaattga
     1141 tggagttact aggaataaaa gatagaagaa tgtatttgcc aaatcaatta tcaggtgggc
     1201 aacaacaaag agtagcaata gcaagggctc ttgtaaataa accatcaatt gtatttgctg
     1261 atgaacctac tggaaattta gacacaaaga cagagtcaga tgtattaagt ttattaaaag
     1321 aatctcaaaa aaaatataat cagacaataa taatgataac acataatata gatataacaa
     1381 aatatgctga tagagttata gaaatagaag atggatttat aagagagtag gtagatttat
     1441 gaaacttaat tatattgtaa aaaaatatat aatgggaaat aagaaaaata cattattaat
     1501 aattgtaagt attgtaattt caacagcgtt gtttttaatt atgaatataa taagtgaaga
     1561 tgcgacaaac ttaatgataa atcaagctaa aaatgaattt acattaaaac atgcacaata
     1621 tatcaatcca aaagacgaag aaataaaata tatagaaaat aacacaagta tagataaagt
     1681 tggaaaatca atgcttttag gaattagtga tattggtaaa ggtcaaacac tacaaattct
     1741 atctcaggat aaagttgctg aagaactaaa tgatatttac acactagaaa aaggtaaatt
     1801 accagtagct gaaaatgaaa tcgctataga ttcatggtat attaaacaaa aaaagataaa
     1861 aaaccctata ggaaaaagga taacattaga ttatagaaga caagggatag atcaagaaga
     1921 tttatatact ggggaaaaag aatttaaaat aactggtatc ttaaatagta atcctatttt
     1981 aaaagctcaa ggaacatcaa ttggccttat aagtaacgat tgtgctatca agaatattcc
     2041 tactaaaaat aaatatgatc aagttatgtt tacttttaaa aaggaaaaaa atatacagag
     2101 acaatcacaa aaacttatta aaaatggaaa tttgaatgag aataacattt attttaataa
     2161 tgaattatta atagctatat ctgatagtat gaatttaaaa ataccttata taatagttaa
     2221 tatagtacta gcactagcaa ctatattatt aatttataat attttttata tattagtatc
     2281 aaatagaata aaggattttg ggatatttag ggctttaggg tttaatccaa atgatatttt
     2341 taaaataatg attttagaag tatctatata ctctattata agtatttcta taggtctaat
     2401 tttaggtggg ataatagcta gtttatcaag ggagtatgtt ataggagtaa tatacaatgt
     2461 caactatata aattctataa aaaaccagaa ctatataaac acatacataa tttctatatt
     2521 attaagttta ggaactataa taatatcagt ttcaaaacct cttatgttat cagttaaaac
     2581 tgatccaatg atttgtataa gaagaaataa tgaaaaagtg gatataaaac aaaattcctt
     2641 tataaataaa tttatgataa aacttttcaa agactatggt aacatagcat caaaaaatat
     2701 acaaagaaat aagaaacgta caaatttatc tatagcatca atggtaatta tatttttctt
     2761 aatggcaaca atatacacaa agtctactag taacttttta agtgatggtg tattaaaata
     2821 ttggatacaa ggagattatt tattacataa tattgatata agtactatac gttcaaataa
     2881 taaaggttat gataaaaatg tactacaaga gataaaggca attgatggtg taacaaaagt
     2941 aaactcatat aggcataagt ggtttaatat aaaaattgat gataaaagta taaataagaa
     3001 ctctgattat tggaaaaaaa ataaagataa tattgaagct agatcagaag taaaagatgg
     3061 aattaaggta tataataatt cttttgaatt tttaggaata gaagatacag atatactaga
     3121 ggatttcttg ataaatggaa aggaaaatat agataaattt agtaaacaac catatctgta
     3181 tataacaaag aaatccagtg attcgcttaa tataaaaaaa ggagatagaa taaaagtata
     3241 ctttgatatt atagattcaa aaacaaataa ttttaccaaa acaatatctc aagaatttat
     3301 agtatgtgga attataacta cattaccagt aacctcacaa gtgggagctg aatttggcgg
     3361 agtaatatca acaaatcaat ttaataagtt tacaggaata tcatcttatg aaagatttga
     3421 catatggacg agtaaactag ccaatgataa atatgttgaa agtgagttaa acaaaataac
     3481 agaaaaaaca aataaaggaa ttttaattcc atacaaagct gaaacagctg aatatgaaaa
     3541 aattgataat caaaaaacac taattatggt attagtaact ggaattatag ttatattatc
     3601 tttatttaat tgttgcaata ctatagttac tagtattaat agcagaagta gggaatttgc
     3661 actatttaga ggaataggaa tatcaaaaca tgaaataaat aaaattgtta aattggaaag
     3721 ttatatatat attatagtaa gcttttgtat atctataata cctattttaa ttgtaagaag
     3781 tataataata aaaccttttg aaagtatcaa tttaataaat tggaaattta taggggctat
     3841 tatactaata gtatttattt tagtatctat aatcatgata actacactaa aaacattgaa
     3901 taaaattcaa aatgaaaatt ttatggaaga aataaagact ttatagtgaa cagcctataa
     3961 attaaagagg ttttatatga atttaattgc aattatcgat aatggtgtag atattgattt
     4021 taaataattt agaaataaaa ataaaataag ttatccaagt tatatgtatg atgtaatagg
     4081 ggtacaatgt atagcaaata taaatattgg cttaataaaa ctctactctt aagtctactg
     4141 tcgttttaac acaagactaa taataagtgt aacctaaaaa ttattgataa tacaataacc
     4201 ttgtttatga taaataacaa atattaagtg ttgtaaagat agtaagttta aaaaaatatc
     4261 aaagatttca atcacaatgt attgtttatc tgtagtgtta gctatttatg gtatatatgt
     4321 atttataaat tgtactgaat atatatatac tatgctatct acaaaacatt taacagtcaa
     4381 aggaaatgaa tataccatta taaattatta tatgagtaac tttagtcagt atataatatt
     4441 tgctatttta cttgcatcaa tgggatttgt aatacaaaag atagtgcata tgcatttcag
     4501 tgagatagaa cttagtggta actattcaac aactgttaga aatataagtg atatctcttt
     4561 agataatgat aatgaaatgt ttaatagagg caatattgaa aatagtattt taaaaaaata
     4621 aataatataa atatataaaa tgtgattgaa taaa
//
LOCUS       DAEHWO010000154         4593 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEHWO010000154 DAEHWO010000000
VERSION     DAEHWO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4593
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.157"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            271..1746
                     /locus_tag="KNP54_003867"
     CDS             271..1746
                     /locus_tag="KNP54_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBF0894715.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1833..2246
                     /gene="speD"
                     /locus_tag="KNP54_003868"
     CDS             1833..2246
                     /gene="speD"
                     /locus_tag="KNP54_003868"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBF0894716.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2276..3127
                     /gene="speE"
                     /locus_tag="KNP54_003869"
     CDS             2276..3127
                     /gene="speE"
                     /locus_tag="KNP54_003869"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBF0894717.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3117..3995
                     /gene="speB"
                     /locus_tag="KNP54_003870"
     CDS             3117..3995
                     /gene="speB"
                     /locus_tag="KNP54_003870"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBF0894718.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4175..4375)
                     /locus_tag="KNP54_003871"
     CDS             complement(4175..4375)
                     /locus_tag="KNP54_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBF0894719.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1847 a          504 c          771 g         1471 t
ORIGIN      
        1 taaaaaaaac aaaataataa aaaataagaa agtttataaa tactaagttt taaaaaaatt
       61 aatataaaca acaaaaaaat aaaaagttta taaatattga tatagctaat gtatatgttt
      121 ttgagtaact tcaaaaaaac acttgtaaaa atgctgagat gttaatataa taaatatcat
      181 gagtttaata aaagtaaaaa taaaaaatag aaataataaa taataaatat taaaaatatt
      241 tgaatataga gaggagatga atttgaaatc atggatagcg agtttgcaaa tgcagttgaa
      301 ttaagctatg agtgtgctcc attattagag tcgttaaagg aatactcaga gaaagatata
      361 gcttgttttg atgtgcctgg acatgtaaaa aatagaggtg tagctatatt aaataaatat
      421 ctaggtgaaa gtctcatgaa aatggatata aattcatcac caactatgga taatgtatct
      481 gcgccaaatg ggattataaa aaatgcacaa gatttgctag cacaagcata tatggctgat
      541 gaggcattct ttataacgaa tggcacaact caagcaatac atgcaatgat tttgagtgtt
      601 ataaaaccag gtgaaaaagt attacttcca agaaatatac ataaatcagt aataaatgcg
      661 ttaatacttt gtggaggaat accaatattt atacaaccag aatttgatga aaaactaggt
      721 ataagtttaa atattactct tgaaaaagtt agaacagaga tagaaaaaga ttgtaatata
      781 aaagcattat ttttccttaa tccaacttac tatggagttt gtgcagacct tgagagtatt
      841 atagaactat gccataaaaa taatgtttta gtgttagttg atgaagctca tggtgcacat
      901 tttccatttc atttagattt acctccttct gcaataagtt tgggagctga tatggtagct
      961 gtaagtatac ataaaactgg aggagcattg acacaatctt cagcactctt attgaataga
     1021 gataatgtaa gttttgaaaa ggttcttcaa tcaatcaata tgctacaatc aacatcagca
     1081 tcttatttgc ttatggcaag tatagatggt gctagagtta atctagttga gaatggtgaa
     1141 aagcaactgt caaaagcatt aaatctatct aggtatgcaa aatctaaatt aaacaaaatt
     1201 gatggaataa aagttttatc tacagaaata ttgaaacaaa aaggtgttaa atttatagat
     1261 gaaacaaaat tgtgtataaa tgtaaaagaa ttaaatttga ctggatttga agtatacgat
     1321 ttattatata aaaatttttc aattcaagta gaattgggag attcatataa tatactggca
     1381 cttgtgtcca ttggaacaaa taaatcagat atagatagat tagtaaaagc actttctata
     1441 attgcaaaga tttatagaaa agaatcaaca ttaaatgaat ttaatatggt tcaaataaat
     1501 ccaattatta aacttaatcc aagagaagct ttttatgcac caaaggaaag tgtagaaatc
     1561 aattcatgta tagatagaat ttgtggagaa tcaataatgg catatccacc aggtataccg
     1621 attattgctc caggagaatt gataacagaa gaaattatgg agtatattat tttcttaaaa
     1681 aatagcaatg catatcttac agatgtacaa gataaaaact tagatagaat attagtaata
     1741 aaataaatta ctttattttg caagggcaag tatttgttaa gtagagttta tcaaatagaa
     1801 cttattaaaa gtataaagga gttggggttg aaatgaaatt tgaaacacta ggaagacata
     1861 tactagtaga atactataat tgtgatgaaa acgtacttaa agacccacgt cttatagaaa
     1921 attttatgaa tgattcagca ttaaatgcaa aagcgacaat tgtggattct gtattccacc
     1981 attttaatcc ttggggggtt tcaggagctg ttataattgc tgaatctcat ttgacaatac
     2041 atacatggcc tgaatatggc tatgcagcag cagatttttt tacttgtggt gatatagacc
     2101 catggaaaag ttttgaatta ttagagcaac ttttaaagtc tgaaagaagc gagtctacag
     2161 aaattccaag aggcttaact acaaaaatta aaaaatattc aaaaaaagat ttaggtaaga
     2221 ttactcataa accagaagca gtataaaaca tacaagagaa agtgaggatt attatatgga
     2281 actttggtat acagaagaat ggacagaaaa tgtaagattt tctataaaag taaataaaca
     2341 tctatttgaa ggaaagtctc aatttcaaag gatagatgtg tttgatagtg atgaatttgg
     2401 aaaatttcta acaatagatg gattaatgat ggtaacatat aaagatgaat ttatatacca
     2461 tgagatgata actcatgttc ctatggctac aaatttaaac ataaagaaag tattagtcat
     2521 aggtggaggt gatggaggta cagtaagaga attaagccgt tatcctcaaa tagaaaagat
     2581 tgacatggtt gaaatagata aaatggttgt agatgtatct aaggagtata tggatatatg
     2641 ctcatgtaaa ttagatgata aaagagtgag tttatatttt gaagatggtg ttaattttgt
     2701 taagtgtgca catgataaat catatgacct gataatagta gattcaactg acccaatagg
     2761 accaggtgaa gggcttttct caactgattt ttataaggat tgttatagaa tactgactga
     2821 tgatggaatt ttagtaaatc aaagtgaaag tccgtatttt gactttaatg ctaaagagat
     2881 gaaaagagct aataaaaaat taaaacagat atttccaata tcagaagttt atcaagcaca
     2941 tataccaaca tatccatctg gtcactggtt gtttggattt gcttcaaaaa aacttaatcc
     3001 agtaaaaaat caagatagaa atggatggga gaaattaagt ttaaaaacta aatattataa
     3061 tagtgatata catttaggtt cgtttatgtt acctcaatac gtgaaggaga tgctagatga
     3121 agaataattt ctatcatatg aacactttta tgagtatgga caaaaattat gaagaatcta
     3181 atcttatagt atttggtgtt ggatttgatg gaactacttc taacagacct ggggctagat
     3241 ttgcaagtag ctctatgaga aaagaatttt acggtcttga gacatatagt ccttttttag
     3301 atttggattt agaggattat aatatatgtg attatggaga tttagaaatt agtgttggaa
     3361 gtacagaaca agtcttaaaa gaaatctatc aagagacata taagattgtt agagattcaa
     3421 aggtaccctt tatgattgga ggagagcatt tagttacatt accagccttt aaagcagtac
     3481 atgaaaagta caatgatata tatgtaattc attttgatgc ccatactgat ttgagggaag
     3541 aatataataa tagtaaaaat tctcatgcaa cagtaattaa aagaatatgg gatattgtag
     3601 gtgataataa aatatttcaa tttggtataa ggtctgggac aaaagaagaa tttaaatttg
     3661 ctacagaaga aaaacacaca tacatggaaa taggaggaat agatacgttt gaaaatatag
     3721 ttaatatgct aaatggaaag aatatttatc taactataga tttagatgta ttggatgcat
     3781 ctgtgtttcc aggaacaggt acaccagaac ctggtggtgt aaattataga gagtttcaag
     3841 agatttttaa gattataaaa aactctaata taaatatagt tggttgtgac attgtagagt
     3901 taagccctga ttacgataca acaggtgtat cgacagttat agcttgtaaa atcttaagag
     3961 agttatgctt aataatatct gataaaatta aatagagtat tttatataaa tagtatatat
     4021 tataatataa gaagttattt taaaaaagtt agtttaagtt tgacgctttt ctaaagtaac
     4081 ttcttatttt tgtaattaaa aataaatata ataaacaaca aaaaagagcc ctcgatagct
     4141 ccttttctaa aatatatata tttaaattaa ataattatat tctatttacg ttttcagctt
     4201 gaggtcctct attaccttga gttatatcaa agctaacctt ttcgccttct tctaaagttt
     4261 tgtatccatc attttgtata gctgagaaat gtacgaaaac atcatcttct ccctctacag
     4321 atatgaaccc aaatcctttt tcattgttaa accattttac tattccgttt ttcattataa
     4381 gaaaacctcc gcattattaa aaaatacaaa ctaaaaaaat aagtctgttc tattaatata
     4441 acataaattt taaataaaag caaataaaat ttttaaaaaa attaattact tttagaattt
     4501 aataaaaatt gttaaattat acagtgagaa gtattgtaaa atttgacgaa aatgtaaatg
     4561 tagataataa atttaatatc aaaaaatgta aca
//
LOCUS       DAEHWO010000155         4546 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEHWO010000155 DAEHWO010000000
VERSION     DAEHWO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4546
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.158"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            54..2465
                     /locus_tag="KNP54_003872"
     CDS             54..2465
                     /locus_tag="KNP54_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBF0894720.1"
                     /translation="MRKYKLKKLSKLLVLLTVCFLIVSTIPVSAEKNKILTGVETAEY
                     SESYLQYLEDVKNGDIAKYNGVIPTPYEMEGTTLKTNVRSSLPASYKSSVSYDPRKLD
                     LTTPAKDQGKLNTCWAFSGMSTLEAYLKLKGYGTYDLSEEHFRWWSTGGIHGWNLTDM
                     TGSSNVTAIGYLTAWAGPKLEKDIPYNFKSEDEGATRPQNMDTAPTQFNVTDVVRISK
                     DKTSVKNAIMQYGAVTSGYAHYSAYLSDDENSYNCNDKSEPLNHSVSIVGWDDNYSKD
                     KFKPSVRPESNGAWLVKSSWGEFNSEKGFFWISYEDKTLLKDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            2762..4339
                     /locus_tag="KNP54_003873"
     CDS             2762..4339
                     /locus_tag="KNP54_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBF0894721.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT         1837 a          525 c          844 g         1340 t
ORIGIN      
        1 ctagatttag aaatctgata taataaaaat taaatacata caagggggta aatatgagaa
       61 agtataaatt aaaaaaattg tcaaagctac tggtgttgtt gacagtttgt tttttaattg
      121 tgtcaacaat acctgtctca gcagaaaaaa ataaaattct gactggagta gaaactgcag
      181 agtattctga atcatatctt caatacttgg aagatgtaaa aaatggagat atagcaaaat
      241 ataatggagt aataccaact ccttatgaaa tggaaggaac aacacttaaa actaatgtaa
      301 gaagtagtct tccagcatca tataaatcaa gtgtatcata tgatccaaga aaattagatt
      361 taactacacc agcaaaagac caaggaaaac ttaatacatg ttgggctttt tctggaatgt
      421 caacactaga agcatatttg aaattaaaag gttatggaac ttatgatctt tcagaagagc
      481 attttagatg gtggtcaact ggaggaatac atggatggaa cttaactgat atgacaggta
      541 gttcgaatgt aactgcaatt ggatatctta cagcctgggc aggacctaag ctggaaaaag
      601 acattccata taattttaaa tcagaagatg aaggagcaac taggcctcaa aatatggata
      661 ctgcacctac acaatttaat gtaacagatg ttgtaagaat tagtaaagat aaaacttctg
      721 ttaaaaatgc aataatgcaa tatggtgcag tgacatcagg atatgcacac tattcagcct
      781 acttaagtga tgatgaaaat tcgtataatt gtaatgataa aagtgaacct ttaaatcatt
      841 ctgtttcaat tgtaggatgg gatgataatt attcaaaaga taagttcaaa ccaagtgtta
      901 gaccagaatc aaatggagca tggttagtaa aaagtagttg gggagaattt aactcagaaa
      961 aaggcttttt ctggatttct tatgaagaca aaactctttt aaaagataca gataactacg
     1021 caatgaaatc agtatcaaaa ccagatagcg ataaaaaaat gtaccaactt gaatatgctg
     1081 gtcttagcaa gataatgtca aataaagtaa cagcagcaaa tgtatttgat tttagcagag
     1141 attctgaaaa acttgactct gttatgtttg aaacagattc tgtaggagca aaatatgaag
     1201 tatattatgc accagtagta aatggagttc ctcaaaacaa ttcaatgaca aaacttgcaa
     1261 gtggaacagt atcatattct ggatacataa atgtacctac taattcttac agcttaccaa
     1321 aaggtaaagg agcaatagta gtagttatag acaacacagc aaatcctaat agagaaaaat
     1381 caactttagc atatgaaact gatatagatg gatactatct atatgaggct aaagcaaact
     1441 taggtgaaag ctacatactt caaaacaata aatttgaaga tataaataca tatagtgaat
     1501 tttctccttg taactttgtt ataaaagcta taacaaaaac atcttctgga caagctactt
     1561 caggagaatc tttaactgga gcagatagat atgaaacagc agttaaagtt agtcaaaaag
     1621 gatggacttc ttcacaaaat gcagtattag taaatggaga tgcaatagtg gatgctttaa
     1681 cagctacacc atttacagca gcaattgact ctccaattct tttgacagga aaagataact
     1741 tagattcaaa aactaaggca gagttacaaa gattaggaac taaaaaagtt tatctaatag
     1801 gtggagaaaa ttctttaagc aagaatgtac aaactcaact tagtaatatg ggtatatcag
     1861 tagaaagaat ttcaggtagt gatagataca agaccagtat atctctagct caaaagttaa
     1921 atagtataaa atctgtttca caagttgcag tggcaaatgg tgtaaatgga cttgcagatg
     1981 caataagtgt tggtgcagca gctgctgata acaatatgcc aataatactt actaatgaaa
     2041 agagtgagtt gcaaggtgct gatgagtttt taaattcatc taaaataact aagtcttata
     2101 taattggtgg aacagctact ttatcatcaa atttagaaag taagctttca aatccaacaa
     2161 gacttgcagg aagtaataga aatgaaacta atgctaagat aatagataaa ttctatccta
     2221 gctcagattt gaaatatgct tttgttgtta aagatggttc aaagagtcaa ggagacttga
     2281 tagatggact agcagtagga gcattaggtg ctaaaactga ttcaccagta gttttagttg
     2341 gaaataagtt agatgaaagt caaaaaaatg tacttaagtc taagaaaata gaaactccta
     2401 ttagagttgg tggaaatgga aatgaaaatg cttttaatga actaaatact cttttaggaa
     2461 aatagtgaat ggaaagatag taaggatata cattttatta ttaaaaaata ttcaatagaa
     2521 gtttataaat ataaaataac aaaacggggt gtctcaaaat gaacttttta gttcatgagg
     2581 cactcttttt tgttgtttta tatttttatc atttaaataa tgaaaaatag gattgtctat
     2641 atttttagat agttttctta ttattgatga aaaatgtaat aattttaaac tgtaaaatag
     2701 tgtaaagtta ttttataata taaatatagt aagattttaa acaaaataag ggggaataat
     2761 aatgaaagca ccaaaaacta ttttaacaat actgacaata gcgcttactt taagtagcat
     2821 ttctataata ccatcatatg cacttacaga ggaaaaatta ataggtaatg gtagatatga
     2881 aactgctgta aagataagtc aaaaggcata cagttctagt cctaatgtag tgctagttaa
     2941 tgacaattca ttagctgatg cactttcagc tacaccattt gcaaaggcta aaggagcacc
     3001 aatacttttg acagaaagtg ataagctaga tgataggact gaaaaagaga taaaacgtct
     3061 aggagctaaa gatatttatt tgataggagg tactgctgta cttaataaag atatagagaa
     3121 caagttaaaa agtaatggac ttaatgtaga aagaattaat ggtaaggata gatatgaaac
     3181 ttcactgatt ttggctaata agcttaagga tataaaagat attaaggaag ttgctgtagt
     3241 aaatggtgaa aaaggattga gtgatgctgt tagcgttggg gcaccagcag ctcaaaataa
     3301 gatgcctata attttgtcta gtcctaagga cggagtagaa gcatttgata aatttataag
     3361 ggatgagaaa gttataaaag catatgtaat tggaggtaca aattctgttt caagagctgt
     3421 agaaaagagt cttcctaatg cagaaagagt gagtgggaaa gatagaaatg agactaatgc
     3481 taaggtcata gaaaagtttt acactgatac aaatttaagt aatttatatg taactaagga
     3541 tggtagtaaa aatgagaatc aactaataga ctcgttagct gttggagtat tggctgcaaa
     3601 aaatgagtct cctgttgttt tggttggtaa taaattaaac acaaaacaaa gggacatact
     3661 tagtactaaa aaattaaata ctataacaca ggtaggtgga aatggaaatg aagaagcttt
     3721 tgatgaaatt aaaagtctac aagaaaaaac tgtgtttgaa gcaaaaactg ttgaggaatt
     3781 aactgatatg ataaatatag caagtcctaa tgatattata aactttaaac caaaagagaa
     3841 tactgtaaat gaagctttta gaatggtaac aaataaacca ataactgtga atataaaggg
     3901 tgattgttca aagactctta cagtagatat gcctaatggt gaagtgaata actatgctac
     3961 tttggtaaat gttatagtta gaaatattgg agaaggtgga tttaataacc atgatacaat
     4021 cactatattg tcagttcgtg acaaaaatgg tagagttata gaaaatacta gaaattcaga
     4081 tatagatacg ttgatgatat tagcttctgc taatgataca aaattgatta atgatggata
     4141 tataggaaaa cttatagata attcatctaa tagtgatata actaataatg gtactataga
     4201 taaaaaagtt aatcaggttg aagatttaga ggctaaagta gattcaattg aaaaagctat
     4261 agattctata agtcaaaaag tcaataaaat acaagatata ctagataagc ttggatttct
     4321 aaagaaattt cttagctaag aatatatata tttaagtgaa gtgtttgttg taattgttct
     4381 aaagttatgt agttaaacag gtttatatac aaatagattt atagataaat atgtagttta
     4441 gtatatattt gaataagctt tggggaggta acatggggat tggaattgaa tgtaacaaaa
     4501 aaataaataa aagtattgac aaaactagaa taaagaaaaa taatct
//
LOCUS       DAEHWO010000156         4397 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEHWO010000156 DAEHWO010000000
VERSION     DAEHWO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.159"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            371..2470
                     /gene="nrdE"
                     /locus_tag="KNP54_003874"
     CDS             371..2470
                     /gene="nrdE"
                     /locus_tag="KNP54_003874"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBF0894722.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDKWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            2483..3454
                     /gene="nrdF"
                     /locus_tag="KNP54_003875"
     CDS             2483..3454
                     /gene="nrdF"
                     /locus_tag="KNP54_003875"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBF0894723.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            3530..4156
                     /locus_tag="KNP54_003876"
     CDS             3530..4156
                     /locus_tag="KNP54_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBF0894724.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         1763 a          463 c          798 g         1373 t
ORIGIN      
        1 tcttgaaagt acttttttca atatatcaga atatattttt aagctattta gagataattt
       61 aaatttttaa acaggacata ataagcttgt attgttttat atttgagttg ataaaaattt
      121 ctttaaataa aaataatgtc aattataaag taataaaagt ttagatataa aaaaatttgt
      181 gtatatacta tatgtagtat ataatagata aagcactgac tatatgtagt gcttttgttt
      241 ttgaaaaata cttattgcat ttctataatt atagattaat tttgggattt caactgataa
      301 gtaccaaaag aaataataag caaattaagt gaaattatgg cacaagatta tgttaaaagg
      361 acggtaaata atgaattgga tagagcttaa caatcaagtg ataattaaaa atgaacaagg
      421 caagtaccaa ttggaaaagg ataaggaagc cttaagtagt tacatagaag aatttataca
      481 gccaaagttg agaaaattta ataacctaga agaaagattg aagtatttaa tagatgaagg
      541 ttattattca aaagaagtaa taaatcagta tagcatagat gttattaaaa atatatatga
      601 tatgattgat aaacataagt ttgaatttca atcatatatg agtgcaaata agttttatca
      661 aaattatgca ttaaagagca atgatggaaa ggaaatatta gaaacatata atgataaagt
      721 gttaattgta gctttgacac taggaaatgg cgataaagat ttagctttaa acttggcaga
      781 taaaatagta aaacaagaat ttcaaccagc tacacctact tttttaaatg ctggaagaaa
      841 aagggctgga gaaatggtat catgtttttt actatctgta gaagatagta cagaaggtat
      901 atcgtatgct atatcttcat caaatcactt atcaaagatt ggtggaggag ttgcactaaa
      961 tttatctaaa cttagagcat ctggcgaatc tatcaaagat atagaaggtg cagctggagg
     1021 tgttgttgga gtagctaaaa tgttagaaca atcatttagt tactttaatc aaatgggagc
     1081 tagacaaggt tctggtgcgg tgtaccttac tgtattccat cctgattttg aattgttgat
     1141 ggatactaaa aagataaatg cagatgaaaa aataaggctt gctacattat cattaggagc
     1201 tataatacca gataaattta tggagttggc agaaaaaaat gaagtagcat atgcatttta
     1261 tcctcatact gtgtataaga aatatggagt ttctcttgat gagatagaaa tggataagtg
     1321 gtatgataaa ctggttaatg atagtgatat aagaaaaaaa gaaataaatc ctaggcagat
     1381 gttgacaaaa atagcacaga tgcaacaaga aagtggatat ccatatgtag tgtacataga
     1441 tacagctaat agagaacata cattaaaaga tgttggaatt attaaaatgt ctaacttatg
     1501 ttgtgagata tttcaatatc aaacaccttc agaaatagag gggtatggag gaaaaaatga
     1561 atggggacaa gatataagtt gtaacctagg ttctttaaac atagccaatg taatggataa
     1621 taaaactata gaaagtacag ttgaaacagc aataagagca ctgtcatttg tagcagatag
     1681 cacagatata aaaccagtgc caacggtaag caatagtaac agcaagtctc attctatagg
     1741 attaggagct atgaatttac atggatactt agtaagagaa aatattttat atacttcaga
     1801 tgatgctata gatttttcta atgtattttt tgcaatggtt agatactatt caattaaagc
     1861 ttctatgaaa atagctatag aaagaaatca aacttttgaa ggatttgata aatcagaata
     1921 tgttaaggga agaaatagca aggttttatc aaaatactat gaacaatctt atctacctaa
     1981 gtcagaaaag gtaagagcat tatttgaagg gatttatata ccaacaaaag aagactggac
     2041 aaaattattg gatgaggtaa aagaaaaagg gatatataat gcatatttaa tggcagtagc
     2101 accaactcaa agcattagtt atgttcaaaa tgctacatca agtataatgc caattactga
     2161 gccagtagaa gtaagaacat atggagactc tactacaata tatccaatgc catttttaac
     2221 aaatgataat atgttgtatt atcaatcagc atacaggatg gatatgagaa aggtcataga
     2281 tttagtggca acagttcaaa accatgttga ccaaggtata tcaacaacac tgtttgttac
     2341 agatgaaaag acaactagag atatagctag acattacata tatgcctata aaaaaggttt
     2401 gaaaagttta tattacacaa gaacaaagat gacaagagat actcatgagt gtctagtgtg
     2461 ttcagtatag ggagagaaat atatgacatt taatttacat aaaatacata atgcagttaa
     2521 ctggaataga gaagaagatg gatttacaca agctttttgg gaacaaaatg taaaacaatt
     2581 ttggcttcct gaagaaatat ctgtttctaa agacataaag gtatggaatg aactaagtaa
     2641 taaagaaaag gaattatata aaaaagtatt gggtggttta acattactgg atacaaaaca
     2701 ggggaataat ggaataccat ctatgatgag tttaacagaa aacctacaaa gaaaagctgt
     2761 cttgtctttt atggggacta tggaagaaat acatgcaaaa agttattctt ctatatttat
     2821 gactctactt tctaatttag aaatagatga attatttgaa tggatagaaa cagaaccaac
     2881 attacaaaga aaggctgatt tagttttagc tcaatacgaa aatactacaa atcaagaggg
     2941 attataccta tcaatggtta caagtgtatt tttagagagt ttcttgtttt attcaggatt
     3001 cttttatcca ttgtatctat ctggtcaagg aaagatggta gctagtggag aaataatatc
     3061 gcttattctt agagatgagt ctttacatgg taagtatata ggattgctag cacaagaaat
     3121 atacgattca tttgataaaa tggataagga gatgttagaa gagaagatgt attctatact
     3181 ttatagcctt atggagaatg agatagagta tacaaatgtt atatacagag aaagtgggct
     3241 tgaaaaagag gttgtgaact ttttaaaata caatgcgaat agagctttag aaaatctagg
     3301 gtttgagaag ctatatactg tagatgctat aaatccaatt gtattaaatg gtcttagcac
     3361 tgaaaccaaa acacatgatt ttttttcaac taagggtaat ggataccaaa aaggagtgta
     3421 tgaggaatta gaggatgaag attttataat ataatttata attatgacac actgttgtca
     3481 cttttagcgt gataatatca atgtataaaa tatatatgga ggtattttta tgaaatatga
     3541 atggagaaaa agagataaag agttatattt acctaaaaag aatcctgtaa tagttgaaat
     3601 accagaacag aaatttatca tgttaaaagg gagtggagac ccaaattcta aagaatttac
     3661 tgaagcaata ggagtacttt attctttggc atatgcaata aaaaccatgc ctaaaaaagg
     3721 aattgtacca gaagggtatt ttgactatac ggtttttcct ttagaaggta tatgggataa
     3781 gggagaaaaa agtaaaggct tagatgtact tattaaagaa gatttaattt acactataat
     3841 gatacgtcag ccagattttg ttacacaaga cctgttggat aaagctactg atatagtaaa
     3901 gaagaaaaaa cctcataatc ttcttgaaaa agttagattt gggtctatta atgaagggct
     3961 atgtgttcaa atgcttcata taggttcata tgataatgaa ccagaaagct ttgacattat
     4021 gaacgaattt tgcaaaaaaa ataaacttat aagaaaatct tacacacatc gtgaaattta
     4081 tataagtgat gctagaaaag tatcgcctga atcattgaag acggttttac gttttgaagt
     4141 agaaagggaa gtataaatat tttgaataat ttataagagt tataaaaagt gaagtctgtt
     4201 gagacttcat tttttgatgc aattttaaaa ttaaatttga tgtttcataa tattttaaaa
     4261 actttctact tttattagtg tgaataactg ttgctattaa ataataatac taattatata
     4321 agtattatta tataatattt atagattatt atataaatag attattagta agatgtatgc
     4381 attattaatt aaaataa
//
LOCUS       DAEHWO010000157         4373 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEHWO010000157 DAEHWO010000000
VERSION     DAEHWO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.160"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            81..1220
                     /locus_tag="KNP54_003877"
     CDS             81..1220
                     /locus_tag="KNP54_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBF0894725.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDELYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLEPLKIYDFISKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            1246..1434
                     /locus_tag="KNP54_003878"
     CDS             1246..1434
                     /locus_tag="KNP54_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894726.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            2218..4002
                     /locus_tag="KNP54_003879"
                     /pseudo
     CDS             2218..4002
                     /locus_tag="KNP54_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
BASE COUNT         1888 a          483 c          714 g         1288 t
ORIGIN      
        1 gataattata aaacaaataa tcaaaaatag tgtaaaaatt aatacttttt gttaatatta
       61 atagataaag ataatctaag gtggtgatta aactgacaat agaagaatac aaaaacaaat
      121 actttactgg aaataaaatc gtactttcta taaatagttt tgataataaa gaactatact
      181 atcatgaaac tgaaaatata ttaaatttaa taaatgaaat agataaatta acatcaagta
      241 agatatttaa aacaatagaa gataaaaatg atttggcact agagtcttat tattctagtg
      301 taatagaagg tgctttttca actagaaaga ttgcaaaatc tataattaga ggaaagatga
      361 aaccaagtaa taaaagtgaa tatatgattt acaataatca tagagcctta gaatatggat
      421 tagataactt agatgaattg tatagtcaca aatttatata tgatttgcat catatattgg
      481 gcgaaaactg cttggattca gaagaatatg agtatagaac tgaaaaagta tatgtatgtg
      541 attcaaaagg tgagattata catacagggc ttgaaccttt gaagatatat gactttatta
      601 gtaaattaat agattttatg gaaaatagca aagtaagtaa tttaattaaa agtgctataa
      661 ttcattttta ctttgtatat gttcatcctt ttagtgatgg taatggaaga acatcaagag
      721 ccttatcata tctatatttg attgataaag gatatgatac tttcaaggat ttttcaatat
      781 catatatgat atctaaaaac agaactaagt attataaggc tatacttgat gtagaaaaca
      841 aaggaaataa tttaactgta tttatagaat ttatgctcaa gtctataata caatctatta
      901 atgagatgcg taatatgcat gatagaaaat ctttagaaag tatattaaaa gaagaattgt
      961 ttgaaaatga cataactcta tcagcaacag aagaacatat attaaaatat atttgcaata
     1021 aagataacta ttctatgaca ttagaaaatt atataaaaaa gaataaaagt agatacttaa
     1081 aggctggaat aaaggaaatt gaattagttg accagttgat ggaagtgttt aataatcttg
     1141 aagagataga gattttgtct aaagaaaaaa atatatataa agttaatgat aagtacttaa
     1201 aaatgcttga tatagactaa tttagataat ctggagaggg aatatatgaa taataagaaa
     1261 aaggcatttt tgatttctgg ggctataaac gtaatttcat taattattgt tttttcattg
     1321 tttcattata atattataga aaatagtaca caaaatatga taataactgt aatcttaatt
     1381 tttatttttg aaatgataaa aataaaaatc atagagaaat actataaact ataaacaaga
     1441 aatatctttt ctaagagcat attgtacaat atgctcttaa tttagttata tagatttaat
     1501 ataaataatg tattttttgt agatgattta tgtaagattt atgaccaatt tgtgtatgat
     1561 ttgtgttctt taatcatgac aatattatat tgtaaaaaat aaatttaata aaaaatgact
     1621 tggaatttat attctaggtc ttttttatat aaaaatttaa taagtttcaa atgttggtaa
     1681 ctttgacagt agaaaacgtc tattgagata acgaggattc taattgaggt ggagagatat
     1741 tagcacttaa agtagtatat gcaacagata taatctttac aaaagtaatt tgaattaaaa
     1801 tgtaaatata aagaataatt aaaaaaatat cgcaattatt tgtttttcat atggataaaa
     1861 ttggttattt aatatataat tacaagtata aataataaaa tttatttgta aaaagagtag
     1921 cacttttaat tctaaaggct acttttttta tacaaaaccc tattttttat aacaattcat
     1981 taacataaaa atcaaactta ccttaaaata taaatttaca aatttttcaa tcaataagaa
     2041 aatttcttta ttccttacat aatgactgca atgtaacaaa ataattacaa attaattatg
     2101 aaatcattat agttagaaac ctctttaaaa ttagatatta agtatccttt agaattagaa
     2161 cgggaacaaa gttaaaaaat taagtaatat caaatggaca agggggaaga aaataaaatg
     2221 aaaataccaa agaagattgc tgcaatgctt acagttacaa tgatagctgg aagttcaaca
     2281 gcaggcatag ctagtgcaca aactgtggca acaaatttaa cagggcaaga aagatatgaa
     2341 actgctgtta aaataagtca agatggatgg aaaaatgctg atgaggtagt aatcgtaaac
     2401 gactcatcta tagcagatgc tctatctgca acaccatttg caaaagcaaa aaatgctcca
     2461 atacttttaa caagtaaaga taaattaaat gataagacga aagcagaaat acaaagatta
     2521 aaagctaaaa aagtatactt aataggtgga acttctgtat taagtacaaa tatagaaaaa
     2581 gaaataaaag atttaaaaat atcttttgag agaatctctg gagctgagag atatcaaaca
     2641 tccttagaat tagcaaagaa attagatgct ataagtgatg ttaagaaaat agctgtagtt
     2701 aatggtgaaa aaggacttgc agatgctgta agtgtaggag caccagctgc acaaaacaat
     2761 atgccagtaa tacttgctga ttctaaaaat ggaacagcag ttgcagacaa atttataaag
     2821 gatgctggaa taactcaatc ttatgtagta ggtggagaga gttcaatttc tgaagctgtt
     2881 aaaaataaac taccaaatag tacaagacta ggtggaacag atagaaatga tacaaatgca
     2941 aaagtaataa aagaatttta taaaaagaca gatttaaaaa atgcttatgt aactaaagat
     3001 ggtatgaata aacaagacca acttatagat gcactagcag taggtgtatt aggtgctaaa
     3061 aatcaatcac cagtagtttt agttggaaag aacttatcag cttcacaaaa atctctagtt
     3121 aactctaaga gttttgataa gataactaaa gttggtggga atggtaatga gacagcattt
     3181 aatgaaatga agtcattaca agaagtaaaa acagttgaag ctaaaacaat ttctgaatta
     3241 aaatcagcta tagataaagc tactgctaat gatgttataa actttaagcc aactagtgag
     3301 gttaaagaag catttacaat acaaactgat aaagcagtaa cagtaaactt aaatggtaca
     3361 tatacaaaga ctgtgactat caacatgcct aatggtgatg taaataacta tgcaaaagtg
     3421 gatgatgtag ttatagatga tgtaaaagat ggaacttttg ttaattatgg aaaaataact
     3481 aacttaaagg ttaatgataa aaatggagcc aagatagaaa ataattctaa aggtgagatt
     3541 ggtagtttaa cagtagcatc tggagcaagt caagtaaaag tgactaatgg tggtaagata
     3601 actacagtta caaataattc taaagggact actatagata ataaaggtac aataagtagt
     3661 gttaagggag ataattctcc aacaataagt ggaaatagtc caagttctaa ctcttcagga
     3721 ggaagttcat caagtggagg ttcttcacat ggaggaggct catcttcagg aggaagttct
     3781 tctaatcaaa catcagtaaa taatgaagca gcaaaaataa caagcgtgcc tacaccagca
     3841 aaagatgcaa ctagattaac tatgccatca gtatcaagtg gatatactat agcaataaaa
     3901 acatcaagta atgagagtgt tataaaaaaa gatggaacaa taatacctcc aaatacagca
     3961 acaacagtaa aattagtatt tacggtaaca catacatcaa gtggtaaaac agcagataca
     4021 aaagaattat ctgtaacagt accagctaaa tcaacagatg aagaattaca agcagcatta
     4081 gacaatgaag tggcaaaaat aacaagcgtt cctgcaccag caaaagatgc aactaaatta
     4141 actatgccat cagtatcaag tggatatact atagcaataa aaacatcaag caataagagt
     4201 gttataaagg aagatggaac aataatacct ccaaatacag aggaaacagt aacattggta
     4261 tttacagtaa cacaagaatc aagtggtaaa acagcagata caggagaaat agatgtagta
     4321 gtaccagcca aatcaacaga tggggaaata caagcagaag tacaagctga ggc
//
LOCUS       DAEHWO010000158         4219 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEHWO010000158 DAEHWO010000000
VERSION     DAEHWO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4219
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.161"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            651..1907
                     /locus_tag="KNP54_003880"
     CDS             651..1907
                     /locus_tag="KNP54_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBF0894727.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNACSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASSVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            1970..3163
                     /locus_tag="KNP54_003881"
     CDS             1970..3163
                     /locus_tag="KNP54_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBF0894728.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            3364..3744
                     /locus_tag="KNP54_003882"
     CDS             3364..3744
                     /locus_tag="KNP54_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBF0894729.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT         1499 a          428 c          756 g         1536 t
ORIGIN      
        1 atatttaaat catgtatcat aatataagca gagtgaagaa aatatttaaa tcatgtatca
       61 taatataagc agagtgaaga aaaatattta aataatatat cataatgtgg agtgaggaaa
      121 aatatttaag ttatgtatca taatgcaaag taaagaaaat catttaaatt atatatcata
      181 aaaataatat gaaatattga acactcataa tattagaggc tttactattt taattgatag
      241 gttatattat ttataacatt aaaaatacaa tttacataaa atagacatat gaaaaataaa
      301 aaattatata ataattatgg gaatgaggtt ctcccttgga tgataatatc ctaaactgcc
      361 aatgagctga tgacttctat gatatcatag atgccaccag ctttttttgt tgtttaaatc
      421 aataaaatgg aggtgaagta cttactaaat ttttattttt taaatttgaa gaaatattta
      481 attaatagaa aaaatagtag attatatgtt aattatttta ttaagaatgg gttaagagtg
      541 tacctatatc ctatcaattt aaaaaacaat tatgatagtc attacattga ctacagttga
      601 tgtaataaaa ctttcaaaaa atcttatgat gcaaatagaa aggaattaaa atgatagaaa
      661 aatttaaaac tttaatatgg attaaaatga taataagaat taaaagcgtt tataaaacat
      721 atggtggact atttttttta ggactcatag gtataccagt tggtgcaatt ataggtctta
      781 tagacaccat atttggaacg gttcttctaa aagttacaga tattcgagaa acatatccaa
      841 tgtatctgat accattttta gcagtagtag gagttgttat tgcttattgc tattttaaat
      901 ttggaggaaa aagtagtaaa ggaatgaatc taatatttga ggtagggcat ggagaagaag
      961 aaattattcc tttaagattg gttccattta taatatcagg tacatggtta acccatttat
     1021 ttggtggtag tgcaggacga gaaggagttg ctgttcagat tggtgcaact ttttcacatt
     1081 gggtaggtaa aaggttgcct ataaaaaatg cttgtagtat ttttctagta actggtatgg
     1141 cagctggttt tgcaggatta tttgagacac caatagcagc aatactattt gctatggagg
     1201 ttttggtagc tggttcactg gagtatcaat cgctttttcc tgcgtttact gcttctttta
     1261 cagcaagttc agtatcaaaa gctttagggt tagagaaatt ttcttttgca ctttcttcta
     1321 aagttgtatt tgacttgtca atattttgga agcttattgt tttaggaatt atttttggaa
     1381 tggttggtgg agcatttgca tggtgtctga aattgtcaaa aagaaaaata ggtaatagat
     1441 taaaaaatcc tatgataaga attgctatta ttggagtatg tcttagtgta ttattccttt
     1501 tattttataa aggaagatat tcaggtttag ggacaaattt aattcaaaat agtttctatg
     1561 gtggagaaat ttattcattt gattggctgt taaagtttat acttacaata ctgactttgt
     1621 cagcaggttt tcaaggagga gaggttacac ctttgttttc cattggagct agtcttggtg
     1681 tattgttagc aggatttttt aatttgccaa ttgaattagt tgcagcgctt ggctatgcta
     1741 gtgtctttgg tagtgctaca aatacttttt ttgcacctgt atttataggg gcagaagttt
     1801 ttggatacag ctatttacct tatttctttg tagtatgcgc tatttcatat atatttaata
     1861 tggataaatc tatttattca ctacaaaaaa tttcaacaaa acaataaata aaacaacata
     1921 atgtatgatt agaagagaaa gaatattaga gaaaggatag ggtaggaata tgttgacaag
     1981 tttagctttg atttttttat taggaatggc ctcgggaggt atttttaaga ggataaagtt
     2041 acctaactta ttgggaatgt tacttacagg aattatatta ggtccatatg ttttaaattt
     2101 gattgataat tcaatactag atatttcttc tgaccttaga aagattgcat tgattattat
     2161 attaacaagg gctggattat ctttagatat aaacgatttg aagaaagtgg gaagacctgc
     2221 tgtacttatg tgctttattc cagctacttt tgaaattatc ggaatgatag ttttagcacc
     2281 aaaattacta ggcgtttcta tattggaagc agcagtcatg ggtgcagtag taggagcagt
     2341 ttctcccgca attattgtac ctaaaatgct taaattaatg gaagaaggtt atggtacaga
     2401 aaaaagtatt ccacagatgc ttttagcagg aacttctata gacgatattt tcgtaattgt
     2461 gatgtttaca gtattcacag gattggcaca aggaaatagt atatcagcta ttagtttttt
     2521 acaaattcca gtatcaatta tattaggtgt aatagttgga gcagtgattg gaatctgttt
     2581 agcagtattt tttaagaagg ttcatatgag agattctgct aaaggggtgt tgcttttaag
     2641 tatctcattt ttaatgataa gtttagagac tgctttagag ggtattgtgc cattttctgg
     2701 attattagca gttatgagta ttgggatttt ccttcagata aaatatcgtg tagttgcaag
     2761 aagattgtcc ataaagtatt caaaactatg ggttggcgct gaaattctct tgtttgtttt
     2821 ggtaggggca acagtagata taagttatgc atttaaagca ggaattggag ctgtaatttt
     2881 aatatttgga gttcttttat tccgtatggt aggagtattc ttctgcctta ttaagacaaa
     2941 tttgacaata aaggaaaggt tgttctgtat gattggctat attccaaagg ctacagtaca
     3001 ggcagcaata ggaggtgtac cacttgcaat ggggatggca tctggacaac ttattttgac
     3061 gttagcagtt ctagctatac ttataactgc acctcttgga gcttttggaa ttgatgtaac
     3121 ttataaaaaa ttattaactt ctgtaaaagg cgagagtaag taaaaataaa gattatttta
     3181 actggtaagt tatattttgg aaaaggatta tactattgaa tacaatataa aaaaatcatt
     3241 tgggagatta agaaggtaga agttaagaac agattttaag gtatgttatg attattagaa
     3301 ttgattttgt gaaattatta ttgtaatatt taattatata gataaagaag cggagtgata
     3361 actatgtgtt taaaaaaatt atcaaaatta gagttagtta ttatgaaatt tatttggaat
     3421 ttagatataa aaaccaattc atatgagatt attgattata tgaaagaaga acataattta
     3481 ccagaaaaag tagctttaaa aactttatca aaactatcaa agaaaagatt cttatatgtt
     3541 caagaaacag gcaagtgtat gtattataca gttgcaataa aagaaaaggc atatttagag
     3601 tttatatcaa gaaatgtgca aaatcttttg aagaataatt ttataaggaa tttattagta
     3661 tcatttcacg aagaggagct aacagaggaa aagataaagt cgttagaaaa ctgggtagta
     3721 aattgggaag aagcttatgt ataaatgtta ttatttttat tacaatttag ataattttgg
     3781 ttttgtaagc tctgcaacta tttttagatg gttgcagagt ttatttttat tttttattcc
     3841 cttaagcaat acttaaaagt aaacgcattt atatttacta acttcaatta cttctaatac
     3901 ttaaattact ttttaaaaat attttgatat gtcatctcta tagtaatcta gaacttgttt
     3961 ctattcttta tataaagttt ttatgaatga tatatataat attcgttcat ttgattaaaa
     4021 ataacaaaat attaaataat tctactctga tagtttgtta aaaaaataat aaaaaatatt
     4081 aataaacaaa aaaaaaatta tcttaagaga ggagaatgtt ctaaaatata aaaaggtttc
     4141 tagatttcat aaaagatact attttagtct tgaaaatatt tagtttgaaa agattttaat
     4201 ttaatgattg attaagtta
//
LOCUS       DAEHWO010000159         4070 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEHWO010000159 DAEHWO010000000
VERSION     DAEHWO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.162"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(<1..1028)
                     /locus_tag="KNP54_003883"
     CDS             complement(<1..1028)
                     /locus_tag="KNP54_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBF0894730.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCV"
     gene            1234..1533
                     /locus_tag="KNP54_003884"
     CDS             1234..1533
                     /locus_tag="KNP54_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBF0894731.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(1772..4000)
                     /locus_tag="KNP54_003885"
     CDS             complement(1772..4000)
                     /locus_tag="KNP54_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBF0894732.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT         1421 a          588 c          537 g         1524 t
ORIGIN      
        1 ttgacacaat cccaccctaa accatatcca agtatagagt cttctccttc aggccataga
       61 ccatttaaat attctttgtt ttccatagct tttactgaag caggagaaag aataccattt
      121 gaatttttca taaatgtttg tgcaaatgta catagatttt ctgcacttga atataaacca
      181 cctgcaccta tagcattaag gttatcttgc ggaactgcat cttcccaata aggcacgtat
      241 gcttttgcta gttttgaact atcaaaacta ttttctgtag tttttgtatt ttgtaagtta
      301 agtggattat ttatgtattt atcaagaaaa ttagtaaatg acataccaga tactctttct
      361 actaaaattt cagctaaagt aaatccatca ttacaataaa cggaaaaagc tcctggttta
      421 gcttttaatc tttgtttttg taattctttt aagaaattat catgaccata agaatcattg
      481 tctgctaata aaatagtgtt tttaaaacta cttcccatca accctgatga atgatttaat
      541 aacattcttg gagtgatttc cttgtatcta tcatcagcca ttttaaattc aggtatatac
      601 tttacaacag gagtatctaa atttaatttt ccatcatcaa ccaacttcat aacagctgtt
      661 gtagtaaaca ttttactgat agatgcgata ctatacatat tatccttatt taagtttttg
      721 ttatcctgtt tgctgtaaac tccaccatta ccagaaatct caattttgcc attatcaatc
      781 aaagcatatt gagcacttac agcaccatac tttgatagca aagtttggat tttctcttta
      841 gcaagagctt tagtttttgt gtaagattcc gcgtttttac tataatcatg taattctata
      901 tcagaacttt gatatttttc ggaattatct tttgtattat cagcaaaagt aatatttgga
      961 gcagcagtaa ataacatact caatactaat gtactagata ataatttaga gagcctttgc
     1021 ttaaacatat tacattacct ctttcccttt ttaataattt ataattagca taacattctt
     1081 aattatttta atcaacagat tattatcaat aaaaaaagct tttataagta tagcttttta
     1141 tataacagag aaaaatataa aaataatatt tgttgttgta taaagaataa agggtatagg
     1201 taatatataa ataaaatgga ggaattttag acaatgtata agaatataaa taaaaagcaa
     1261 cttaaagaaa tgatgaaaaa tgaaaaggat gttttattat tagatgtaag aactaaagat
     1321 gaatttaagg aatataaaat agaaaatgct ataaatatat ctttacaaga gttaatcaat
     1381 aatatagatg aaatttacga ttataaagat aagaaagtag tagtttattg cagaagtggt
     1441 catagaagtg ttactgcatg taatttgtta gctgaagaag gttttgagca tttatataat
     1501 ttaaattcag gaataattga ttatatgagt taaataatgt aagttataca ttaaatacta
     1561 tgtatagctc tgcttattaa gtaggaatat atctaaatat ttataagata aatttaggaa
     1621 agaacgaatt ttttcgtttt tttctatgac agtttttgta gtaaatatta gtttttaagt
     1681 tggaaaaagg tagtagcttt ttagctacta ccttttaata tgaacttaga atattattaa
     1741 aaaaaatata tttaaagaca gaattaattt tttaatgacc agttaaatta ctatcgccga
     1801 atttatcatt aaatggtttt ataactctat ttataggtcc ttttagaagt acatttaaac
     1861 aaatagacag aatcataaat agtaatagaa ctagtatatc tttagttaga tttggagcat
     1921 atataccacc aactgcttcc cttgtagcac ctattgcata ggtaaatggc attatagggt
     1981 ttattctttg gaagaatgta ggtgtaacct gtatagggaa tgtaccacca gaagaaccaa
     2041 tctgaacgac taatagtact attgcaattg cttttcctac atttccaaat acagaaacta
     2101 aagaatacac tataaagtta aataccatac tagtaaacat aagcagaact atcaataaaa
     2161 ttggatgttt tgctgttact cctaacaata atatatctcc agttcctatt ataaaacctt
     2221 ggacaagagc tatacttaaa aaagtaaggc ctcttccaaa gtaaatttca taaggtttat
     2281 agtttccatg tacagatgta gacaatagtg ctgaaataag taatatacca acccatgtag
     2341 aaagaacact ataaaatggt gtcattgcag aaccataatt ttcaattgga tataatttct
     2401 ctgttttcac ctcaacaggt tcttttaaga aattagactt tgtcaatata tcactttcaa
     2461 gcaagctgac taattttttc atatcttcac cattactaat tttgcttaaa gtatcaatca
     2521 aatcatccaa cattcctttt gctaaaggaa gtctttctct tatcaatgat atactttcct
     2581 gtgcatttcc tgaaagtttt agagaagtag taagtatttc ttcaaccttt ggaagttttg
     2641 cttctgcctt atctaaaaca gtaattatat catttgctac ttttatactg tttgcaaata
     2701 tactatttat aggttttgat atttttgagt caaaattatt taaaatattt aaattaattc
     2761 ttccaatacc atttgataga cttaaaacat tattcaaagc acttatagat ggttgttgtc
     2821 cagatataac tttgttttta atatcattta atgttgatat agatgaatct attttattgc
     2881 tagagtcttc aagattatct attacatcat ccaatctatt atttgatgta agttggttta
     2941 atttagttaa aaagtccacc aaagtatcgt ttaaagattg caaattagaa agtttttctg
     3001 ataaattatc tatcaactta ggtacatctt cactgccact atttactgca tcaattaaat
     3061 ttaatgtaag agaagaagca gaagatgaaa ggtcaaccat taaatttaag tcagacttaa
     3121 taagaggaga aagttcgtct aaattatcat ttgtatcctc taagaatttt tttaagtcac
     3181 ttgataatag ttttgtatca ttcagagtct ttttaattgt aggtaaatca gatttaatat
     3241 ctttaactgt atcagataat tttgaagtag catcagaagc taaatcaaca gtcttattta
     3301 tatggtcaaa tctcttttga aggtcaataa gggaattttc aacttttgtc aattttggaa
     3361 gactgtgttc aattcctgca ccaactccgt ttgatatacc aagaacgatt tcactaactg
     3421 tttttactat agtctgatta acctgtagtt gtattgtaga agcaccttta tctgtaatct
     3481 ttggtgcaac tgcatttatt ttttcattaa cagtatagat aatttcgcct tttttaacat
     3541 catctgtaat taaagatgtc aaatcttttg taaaattttt tggaatctta agtgatgcat
     3601 aataagtacc ttttttaaca ccttcaagag cagttttttc atctacaaac tgccaaccta
     3661 aactcttgtt atctttgagt tgttcaatta attggtctcc tacattaatc ttttgtcctg
     3721 ctatttcatt tcctttatct tcatttgtta ctgctacaag catattagca gtgcttccat
     3781 aagggtccca agatgccttt atattgaacc aagcatacag agatggtaaa aaagcaagac
     3841 ctaaaactat tacaagtacg gcataattgc cacgtatatc ttttaggtca cttttaaaaa
     3901 tttctaatat attttttaaa ccctttgaag gtcttaaatt cttgatatta ttccagttta
     3961 aaatttcttt taaactatta gtttttttca aatgtctcac ctcctaaaat attttgataa
     4021 agaaaaaagt tagatttata atcaatttta aattatatta ctttttacac
//
LOCUS       DAEHWO010000160         4047 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEHWO010000160 DAEHWO010000000
VERSION     DAEHWO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4047
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.163"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            63..461
                     /locus_tag="KNP54_003886"
     CDS             63..461
                     /locus_tag="KNP54_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBF0894733.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            449..1387
                     /locus_tag="KNP54_003887"
     CDS             449..1387
                     /locus_tag="KNP54_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBF0894734.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1771..1995)
                     /gene="secG"
                     /locus_tag="KNP54_003888"
     CDS             complement(1771..1995)
                     /gene="secG"
                     /locus_tag="KNP54_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBF0894735.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2588..3880)
                     /gene="eno"
                     /locus_tag="KNP54_003889"
     CDS             complement(2588..3880)
                     /gene="eno"
                     /locus_tag="KNP54_003889"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBF0894736.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1391 a          649 c          457 g         1550 t
ORIGIN      
        1 tatataaaat ttaataactt atataaattt aactaattta tataaaatct taaggagttg
       61 ccatgataaa aaaaatagaa catgtggtca ttactaataa taatatagaa aattatatca
      121 atttttataa aaaatttggt ttttcatcta aagaaatgag caaaaattat aaacttaatg
      181 ctagaaatgt taagataaat cttaacataa aaggttataa atttttacct tatgttaaaa
      241 attcaaaagc aagtagagat aacttatgtt ttaaaataaa cacaaatatt gatgagccaa
      301 aaaaatactt agaacaaaat gagattcaaa ttaagagagg aattgtagaa tgtacaggtg
      361 tctttggtaa tatgaaatct atttatttga aaaaaactaa tggaaattta attgaattat
      421 caaatcatag aatcacggag agtaaacctt ggaaaattta atcctatcaa taaatgttgt
      481 tcttcctttg tttctcacaa tgtcacttgg atatgttcta aaaaaattag gtctatttga
      541 tactcatact ttaaataaaa tgaataatgt ttgcttcaag tctttcttgc cattattatt
      601 attttttaat atatacaata cagatttaga tggttctctt aattttaagc ttatggctgt
      661 agctgttata attatttttt caatcttctt aatcttagtc tttattattc ctaaaattga
      721 aaaagataat aagacaaggg gtgcattaat acaaggtgta tttcgtagca atttcgttat
      781 atttggtatt cctgtgacaa tttcactatt tggcgataag agtattggag tcacatcttt
      841 attaattgca gttattgtac ctatgtttaa tgtattatct gttgtaattc ttgaaatttt
      901 tagaggtggc aaagtaaata taaaacatat gattaaaagc gtcttaacaa atccactcat
      961 aatcgcctct tttataggat tgacaatgct aattttaaat attaatatac ctacattttt
     1021 acacaaaact attggtgata tttctaaaat agctactcct ttatcactta taattctagg
     1081 cggctctttt agtttttctg ctataaaggg gcatataaaa cccattatat tgggcgtatg
     1141 tggaaaactt atacttgtac ctgctatatt tttaccaatt agcatttttc ttggatttag
     1201 aaatgtagaa ttagcttcac ttatgataat gttatctgct ccaactgcag tttcttcatt
     1261 tacaatggca caacagatgg attctgacag tgaattagct ggacaaattg tagtatttac
     1321 ttctggattt tctataatta cagtattttt aataatattt attttaaagc agaataatct
     1381 tatttaatga tatttgataa cacaaattgg tattataaga aacatatata aaactgattt
     1441 aatcgcgtaa aaacatatta ttatactatt tttactatat aatataactt tgtgtatatt
     1501 atctcattaa acatggtgaa agtagtgttg ctatatattt tttagtttga agaaaatata
     1561 taaatacaaa caatatataa atacaaataa taaacgccac caaatagtca atctataaaa
     1621 taaaaactgg actaatcata taaaatcatt agtccagctt ttattttacg tactttttat
     1681 gttgatgtac ttttattaaa aactaaattt aatttttaaa tgtctagcaa atgcactaat
     1741 taaataatgg ccagttattc aacaatatca ctacttctta actataagta atgccaatgc
     1801 atttataaaa aataatactg ctgttatctt tgtaactcta gcaagaaatg cttgttttcc
     1861 ttttggttta aagtaagctt gacttccttc tccaccaaat tctgaaggta aagcattctt
     1921 agaatcttga ggcattatgc taattactag taaaatccct agtactactt gcacacccat
     1981 taaaatgttg ctcattcttg cccctcctat ctgtttatta cttaaatttc attactcttt
     2041 agtgtatcac aataatatag ccatttcaag actattatgc tataaataac atacaaaaaa
     2101 atatattgtt actataatat attactatat tctcaatata aaaatgaata aaacttagaa
     2161 gagaaaacta tttaaattaa tacataaatt aacacttaaa ataatctact ctcattgtat
     2221 atattataaa tagccaccaa aataaaacaa tcattttaaa atattgatat aacttttaat
     2281 ttcaacataa tttaaaataa ataatccaca tttagcaata atacttcaat gacaattatg
     2341 attaaatcaa aatatgtctt cacttttatt ttttaataaa aacctcctat gcaattagat
     2401 aaaaatgaga tagaaacatt tattcatatt ttttctgaat ctatgaataa aattaagtaa
     2461 taaaatataa aaaaggataa gtgaattgaa aaatcaatta acacttatct cttttatatc
     2521 ttataagatg agcttaaata tcttatattc tctcttcatt aatctttttt agtaaccatt
     2581 ttaataacta tttttttaag ttatagaaag attttaatcc acaatatcta gcttgctctc
     2641 caaccatttc ttctattctt aataattggt tgtacttagc aactctatca gttcttgatg
     2701 gagcaccagt ttttatttga ccagcattta ctgcaacagc taaatctgct atagtagaat
     2761 cttcagtttc tcctgatctg tgagatataa cagcagtata tcctgctctc ttagccattt
     2821 ctatagcatc taaagtttca gttattgtac ctatttgatt aactttaact aatatagagt
     2881 tagctactcc attttcaatt cctttttcta atctctctgt gttagtaaca aataagtcgt
     2941 caccaactaa ttgtaattta tttcctaatt tttcagttaa taatttccat ccatcccaat
     3001 cttcttcgtc taaaccatct tctatagtta ttattgggaa gttgtttgac caatcttcat
     3061 ataaagcaac catttcagca gcagttaact cttttccttc tcctgctaaa acgtattttt
     3121 tagtttcttt gttgtacatt tctgtagcag caacgtcaag acctaacata acgtcttcac
     3181 ctggcttata tccagctttt gttatagctt caactattaa ttctaaagct tctctgtttg
     3241 aacctaagtt tggagcaaat ccaccttcgt cacctacacc acaagctaat cctttttctc
     3301 ctaaaacttt ctttaacgaa tggaatactt ctgctcccat tcttaaacct tctttgaaac
     3361 aacaagctcc tactggtaat atcataaatt cttgaacatc aacgttgtta tcagcatgct
     3421 ctccaccgtt taatatgttc atcattggaa caggtaattg tttagcattt actccaccta
     3481 ggtattggaa taatggtaaa cctatttcat cagcagctgc tctagctact gccattgaaa
     3541 cacctaatat agcattagct cctaatttac ctttgtttgg agttccatct aattctatca
     3601 tgattgcatc tatagctggt tggtcaaatg catccattcc ttctatttca ggtgctatta
     3661 tttcatttac gttagcaaca gctgtttcta caccttttcc taagtatctt cccttatctc
     3721 catctcttaa ttcaacagct tcaaaagctc ctgtagatgc tcctgatgga actattgctc
     3781 ttcccattgc tccatcttct aatactactt caacttctac agttggattt cctcttgagt
     3841 ctaatacttc tctagcatat actaattcaa taactgacat ttgtatatct cccttcgatt
     3901 ttctattagt taaattttca tttactgtaa acatccgtct actattttaa tctactttct
     3961 atattatagt acataaagtt gcttttgaaa attaggtaca aatttatttg atgggtaaat
     4021 ttgtaaaagt tcctattttt attttat
//
LOCUS       DAEHWO010000161         3815 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEHWO010000161 DAEHWO010000000
VERSION     DAEHWO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3815
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.164"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            438..2249
                     /locus_tag="KNP54_003890"
     CDS             438..2249
                     /locus_tag="KNP54_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBF0894737.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVATVLSKTFNIKETCARICSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSMMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2337..2918)
                     /locus_tag="KNP54_003891"
     CDS             complement(2337..2918)
                     /locus_tag="KNP54_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894738.1"
                     /translation="MSYLLKINQFERSYDIGIFKNEQSIYKFIEKIPFVKKDSSNFNY
                     TNYYMEFEAIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(3354..3560)
                     /locus_tag="KNP54_003892"
     CDS             complement(3354..3560)
                     /locus_tag="KNP54_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894739.1"
                     /translation="MNQSQEKDLEFIKNHWDLTIIEKERNVTRIIRYSLIILAIIAFF
                     LPTKIKFSIYIFISLFCWLMYLVL"
BASE COUNT         1460 a          376 c          518 g         1461 t
ORIGIN      
        1 tttaagtaat ataccaaaaa aaaggaatat atttacataa tatgataaaa taaattcaaa
       61 gagttaaatt gtaggtaaat agtattttaa ttatttatta aaatatagat tatgtatatg
      121 ccaaatttaa aaagagacat aaagacatta tacaaatata ttattggggt gatattttgt
      181 aagaaaagaa gtgatgcagt aaattaattg agtaatttaa aaatgattta atgataatgt
      241 tgatgaatgt ttaaaaagaa attttagaaa aacgtatatt gctgtttgtg ttggaggtga
      301 tgaatttgta gaatttatag ggtataaatg attaaactat ttaagataaa tacatatcac
      361 tgtaaaatat tgataatcat tttttataag agattgatta tttgcaaatt atatatatta
      421 caaatgaggt aacaataatg aagaaaaaat atgatttttt aatttattct gctatttggc
      481 tagttattat tattcttttt atattttctc tatatcatag tatagagcat attaaaatta
      541 taagtcacac tggtactatt cgcagtgaaa ctcaaaaggt tgttaagcaa gaattgaata
      601 atgaaagaaa tgatgacttg ataaaacgac tggataatat tctgataaag ctaagaacag
      661 gtaatggaga aaatggattt caaagatgtg ataataaaga atttcaacaa aaactaaatc
      721 aaatggattc tatgtgggaa tctatgaaga aagaaattat aaaagttaga aatggtgctt
      781 caggtgataa attatataaa ttgagtgaag agtattctgt gttgtctaat caaattgttt
      841 ttatatctga aaaacactct aatgcaaaat tgtattcttt tgctactgca ctatttattt
      901 atcttatatt ctcaacaata agtcttttaa tttgggaata ttataataaa aaaaggttta
      961 aaagaatatt ttatactgat aatttaacaa aaataaaaaa tcaggttgca tttgaaaaca
     1021 gagcgattga aattttgcac aatgcatcta acaaagagta tgtactgcta aatattgata
     1081 ttgacaattt taaatatatt aatgatacac atggatatga atatggagat aaagttctaa
     1141 taatagttgc aactgttctt tctaaaactt ttaatataaa agaaacttgt gcaagaattt
     1201 gttcagataa ttttgtaata cttgcaaaat atagagattc tcttttagag gatattcggg
     1261 aaatgctaac taatgctata atctctgaat tagatatgaa tgtaactcaa actatatctt
     1321 attgtatagg agcttactta gttgaaattg ataatttagg ttataaatct atcaattcta
     1381 tgatggataa ggcaaatatt gcacacaagg taagtaaaac aagaggaatt tcctccacag
     1441 tatggtataa tgaaaatctg ttaaaacagt tacaaatgga aaatagtatt tataattata
     1501 tgtataaagc gatagaaaat gaagaatttc atatgtattt gcaacctaaa tttcaaatat
     1561 cttctttaaa tgttgtgagc gcagaagctc ttgtaagatg gttttctcca gaacttggtt
     1621 ttttatcacc agatgaattt attccattgt ttgaaaaaag tggatttatt attgaattgg
     1681 acttttatat gttaaaaaaa gcgtgttcat ttgtaaaaaa aacgtttatg aaaaaaaatc
     1741 aatatacata tccgattgca gttaattttt caagggttac tatttaccaa aatagttttt
     1801 atcaaaggtt tttagatact gttaaagaat atgaaattcc ttttaagtat atagagatag
     1861 aggtaactga aagtgctttt aatgaaatat ctcaaccagt tatttcaatt ttagaggaac
     1921 ttaaaaagtt aggattttta atttctatgg atgattttgg atcaggatac tcttcattaa
     1981 gtcttttatg ttctctatct attaatggat tgaagttaga taaaagctta cttaaagaaa
     2041 catttaaccg ggagaaagta tatagtatta ttcagtgtat tattgaaatg tcacatcgta
     2101 taggcatgtc tgttgtatgt gaaggtattg aaactaaaaa agacttggaa tttttaaata
     2161 cagttaaatg tgatgtagga caagggtttt atttttctaa accgatagaa gaaaaagaat
     2221 tttttaacaa atatgtaact aaaaaataat ataattattt ttatcagtct atacattgag
     2281 tcattttata tctcgttaaa tgactcaatg cactgttatg tattttaaaa tataaattat
     2341 ttaaaacgtt ttttatactt atatagaaat tcttctatat tttttgattg ttctcttatt
     2401 tcaactgctt ctatatctag taaataaagt atagaatcat ttgtaagttc aacatattca
     2461 ccatcttctg aaccgagtgc atgtctctca atttttaatc ctttttcttc ataatatttt
     2521 tttgtttcta tatataatga ttctcgcttt tgtatgtagt ctttcacttc attatttgga
     2581 aagttatatg aatccactaa tgtttcgcca tttataaaag ttttctcggt agcaactttt
     2641 tcatcccaac aatggatttc ttcccaagta aaaaatatct cagttccatc tggaatgaat
     2701 gaaaacctgg taataatata taaataatta ttgaaattta cttcataata ttcaggaata
     2761 gcttcaaatt ccatatagta atttgtataa ttaaagttac tactatcttt ttttacaaat
     2821 ggtattttct caataaattt atatattgat tgttcatttt taaaaattcc tatatcatag
     2881 cttctttcaa attgattaat ttttaataaa tatgacatat attctcctta tttgttgaaa
     2941 tataattttt ataactctac taattttaaa catttttaaa taaatatttg tatatacctt
     3001 atataatatt atagtaatta gttttaaatc aatagaatag tatgtattta tctaatgcgg
     3061 caatataatt taaagctggt gttgtagaaa aactaagagt gaatatagca aagagaagca
     3121 atagtatttt aaactttgtc tctcttattt tttgaaaact aacattaaaa cataaggtat
     3181 aaataatatt atcatataaa tgaaaacaaa tttgaatttt tctctggtcg atgtatatag
     3241 taagtttgtt gatatgagaa aaattattat tgataatata catgcataga aaggaaatgg
     3301 tatataatat tttcttaagt ttctttttta ggcatttcta ttggcatttt aggctatagt
     3361 actaaataca ttaaccaaca aaataatgaa ataaatatat atatagaaaa cttaattttc
     3421 gtgggaagaa aaaaagcaat aatagcaagt attattagag aataacgaat aatacgagta
     3481 acatttcttt ctttttctat gatagttaaa tcccagtgat tttttataaa ttcaaggtct
     3541 ttttcttgac tctgattcat ttaatcatct cctgttaata gtataatttt aaagctatta
     3601 ctttgtttta ttttaacata tttatacact aaagtgaatt ttatgattag atttatttaa
     3661 ttatttctga attaaaactt attagaattc tctattttga taatttcaaa ctctattgat
     3721 tgtatgataa ttgaaactat aggatatgta ggataacaag tttcaaagta gttaaaataa
     3781 aaaagataat gatattatta atttagaata aattt
//
LOCUS       DAEHWO010000162         3708 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEHWO010000162 DAEHWO010000000
VERSION     DAEHWO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3708
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.165"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            38..691
                     /locus_tag="KNP54_003893"
     CDS             38..691
                     /locus_tag="KNP54_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBF0894740.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            832..2103
                     /gene="brnQ"
                     /locus_tag="KNP54_003894"
     CDS             832..2103
                     /gene="brnQ"
                     /locus_tag="KNP54_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBF0894741.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            2305..3492
                     /locus_tag="KNP54_003895"
     CDS             2305..3492
                     /locus_tag="KNP54_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBF0894742.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
BASE COUNT         1369 a          401 c          674 g         1264 t
ORIGIN      
        1 aatatcaaaa ataatataat ttatagtgga ggggaaaatg actaaaatta ttaaagtgca
       61 aaaacctaaa tttacaggag aattagaaat tattgaaaat cttgaagata tacttgaaga
      121 tatatttaat gatgaaaaaa tatttaataa aattatagaa aatgaagtta taagtgattt
      181 agattctgta agagttagct ttgaatcttg tatatttaga aatgtgtctt ttgaaaattg
      241 taatttaaaa aagattgatt tacttgatgt ggtatttgaa aactgcaatt tatcaaatac
      301 attttttgat ggaggaagta tatacagagt tgaatttaaa aatagtaaat tgataggagt
      361 tagatttgat gattgtatac ttaaaaacgt tttgttcaag gatgttttag gtaagtattc
      421 taacttttca ttctctaaat ttaagatagt ttctatctta gattcaaatt ttgaaaattc
      481 tgtatttcaa gaagtaaaag gtgacaatct agtatttgag tatacaaatt taaaaaaagc
      541 aaactttaat ggaactaaac tttctggcat agattttact actaataata ttgagggaat
      601 tgagattggt atagatgata ttagaggagc aatttttgat gtgtcacaag caattgattt
      661 aacgaaattg atgggaatta tcataaaatg aaaaaaatat tcataaaata aattgggaaa
      721 acgttaacaa tgtgtgaatt tttaccagat tgacattttt ctgaaaataa agtaagatta
      781 tcttaatatt caaaatattt tcaaaggggg taatttagtg tgagtaagca gatgagagat
      841 atttttatag ttggttttgc tttattttct atgttctttg gtgcaggaaa tcttatgttt
      901 cctccatttt tagggatgga atccggcaaa gactggttaa ttcctcttat tggatttgtt
      961 gttgcagatg ctggtatagc aatgcttgtt attatagcaa cagcaagatg taagggaagc
     1021 atggatgatg tacttaggag agctggtaaa gggttagcaa gagtaatgag tgtagctgct
     1081 ctagcatgtt tagcacttct tgtaatacca agaacttgcg caacaacata tgaaatgggt
     1141 attatgccta tatttggaga ccatggtcca gtagctaaag ctgtattttc aataatcttc
     1201 tttgggctaa ctttagcatt tactattagg tcttctaagg ttatagacat aataggtaag
     1261 tatttaactc cagcgttatt attagtatta tttgttttaa tagtaaaggg tataatttct
     1321 ccagcaggac ctatgagtcc tgagcatatg atagataaaa atctatttgg tgaaggtata
     1381 tcacaaggtt atcaaacaat ggacgctcta ggtgcagcat ctatggcaac tataatgttg
     1441 atgtctataa tagctaaagg atatacatca gataaagacc aaataggaat gactattaaa
     1501 gctggttttg tagcctgtgt atttctagca gtagtatatg gtggtcttac ttatttaggt
     1561 gcaacagttt caactttata tgatactagt atacctcaag catctttatt agttgaaata
     1621 actagtatat tgttatatgg tcaagtagga aaggtaattt taggtgtaat tgtggcactt
     1681 gcctgtctga ctacttctac aggtttaaca gcatcaatat caacttattt tgaaggaata
     1741 agtaaggcga gttataaaca actggttata ggtatatgtg tagctagtat gcttatatca
     1801 aatttaggtg ttgattctat aatagccata tcagttccaa tcctacaaac tatatatcct
     1861 gttttattag caatagttgt tatggagttg gctggtaaac atataaagaa tgataatgct
     1921 tttaaaggtg cagcatatgt tacattagtg attagtttat tatcagctat aaatggaatg
     1981 acaggagctg ttccatttat acaaagcttg ccacttgcag gtttgggctt taactgggta
     2041 ataccagcta tattgggtgg aatagttggt aactttataa aaagcaacaa acaagtagca
     2101 taataatttg taattaattt aattttataa tatattaatt tttagtacta tgggtaggtt
     2161 taatctaaac ctaatctacc catagtactt tttagattgg attataatag catgtatata
     2221 attttttata atataatttt tctttgaagt atgataaaat tagtaatagt gataagaatg
     2281 tacaaattta ggaggtttta attaatgctt agaaaaataa cagcatttat gctatccata
     2341 tgtttaatta ttggacttac aggttgtagt ttacttgtag gcaagaaaga taaagagaaa
     2401 attatagatg attttaaagt tgcagtggta actcaaccat tatctgaaaa taaagtacaa
     2461 tacaatatgg tggaagagat ggcaaaagaa tatgaggaag agaataaaat tgataaagac
     2521 aaagatggtc aaactaaagt taaacaaact ataaagcatg ttgtattgcc agagaatttt
     2581 acttctaata tagacagtgc tattaataag atagtaaagt tggctgacga taaagaagtt
     2641 caggctattg tagtttcaac tgaccaagca gggcttttac ctgctttaca aaaggtaaag
     2701 gaaaagcgtc cagaaataat aactatttct gcccctatgg gagatgataa aaaccaatta
     2761 agccaatttg ttgatgtgaa tctaggggtt agtgcagagg aaagaggaaa agtattagct
     2821 gaacgttcaa aagaaatggg agcaaaagct tttattcatt atgcctctac agatgatttg
     2881 aaagatgtta atatagccaa aagattagaa atgattaaag agacttgcaa aaatatagga
     2941 ttgccatttg tacaagttaa tactccaaat ataaatactg aagaagacaa aaacaaagtt
     3001 aagcagtttt taaatgaaga tattgaaaaa caagttaaaa aatatggaaa agatataaat
     3061 gtatttggtg taaatgagta tatggatgaa gttatattga ctaaggcttt agaattaaag
     3121 tatatagttg cagagcaaag caatccatca ccaatacaaa catatcctag tgttatgggt
     3181 ctaaaaatat ctgaaaaaga tgctcaaaat tatgataaaa taaacgacat gataagtgaa
     3241 aaggctaagg cttttggcat gtcaaataga cttggtggat atcctatgcc aatggatgct
     3301 tttctaccat cagtagcaat ttatcttgct actgaaatgg tgaaacaaga tttaacacaa
     3361 gaagatgtat gtgacccaga ttatttagag gcgtttacag aattaagatt tggaatcggt
     3421 tcagaattta ctcctttaac agaggtactt tataattatc aatcagtaat tttaagccaa
     3481 ttaatttatt aatattaagg acgtgtctca aaatgaactt tttagtttat gaggcactct
     3541 ttttctgtta aatcaaatat atttttatct ttttaacaat taaaaagaag cttatccata
     3601 tgttgagata gcttcgtttt taatataaat aagttttatt attttataaa aaatttatag
     3661 aaaaataaaa aattataatt atatataaat tttgataaag taaagatg
//
LOCUS       DAEHWO010000163         3357 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEHWO010000163 DAEHWO010000000
VERSION     DAEHWO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.166"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            40..984
                     /locus_tag="KNP54_003896"
     CDS             40..984
                     /locus_tag="KNP54_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBF0894743.1"
                     /translation="MKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMS
                     IDNNSKEKAIKLIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAIL
                     NELIIDVANPLDVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKK
                     DDLSSKLFYEQKLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQN
                     IKQEIYNLYKAHRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVF
                     ENEDWINGFSVFCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            1038..2162
                     /gene="wecB"
                     /locus_tag="KNP54_003897"
     CDS             1038..2162
                     /gene="wecB"
                     /locus_tag="KNP54_003897"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBF0894744.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            2240..3214
                     /locus_tag="KNP54_003898"
     CDS             2240..3214
                     /locus_tag="KNP54_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBF0894745.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNGKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT         1405 a          331 c          594 g         1027 t
ORIGIN      
        1 aaagatagga gtctagtaaa taatcaatat aaaggtaaga ttaaatcggc caatttatct
       61 gtagattatg aaataaatca agttatgaag gatatagata aattgggatt gaatacagta
      121 aatgtaccta taattataaa tgtagagtcc attaattctg atattatgtc aatagataat
      181 aatagtaaag aaaaggcaat taagttaata aaaaaattaa ataaaaaagg tatttcaaca
      241 atattagagg catatccatg gattgaaaat ggaaaattgt atgagactga ctggaaccct
      301 ataaataaaa aaagattttt ttatacttgg caaaatgcca tattaaatga acttataatt
      361 gatgtagcaa atccactgga tgtaaatgtt ttaaatattg gttctaattt tgtacatttg
      421 gaagaatatc aacaaaattg gggtgaaata atagattttg tacaatccaa atttgacggt
      481 cttgtaacgt acagaactaa ttggtggtat acaaaaaaag atgatttaag tagtaagttg
      541 ttttatgaac aaaagctgaa caataatttt tttgataagt tagattttat atctatagca
      601 gcatattttg agttaagtaa taaacctgtt aatacagtgg atgaattaat ttctgcctta
      661 cactcatcta ctgtaaacaa tagaggacaa aatataaaac aagaaatata taacctttat
      721 aaagctcata gaaaacctat attttttgga gaattaggtt tttcaaatag agaaagtgca
      781 agttctcagc cgtggaatca tactccttca aaagctgtaa atggcgaaga acaagcaagg
      841 tgttttgagg catataagaa agtttttgaa aatgaagact ggataaatgg tttttctgtg
      901 ttttgtgtag gtaaaataga tgacgaaaaa aatttttacc catcaaaaga gagtataaaa
      961 gttattaagt cttggtatga ataattttga aagtgtagaa tttatataga ttaaatagat
     1021 gattaggaga gatataaatg aatgacatca aggttatgac tgtatttgga actagacctg
     1081 aagctatcaa agtagcacct ttaataaagg aacttgaaaa aagagagaat ataaaaagta
     1141 ttgtttgcgt tacagctcaa catagagaaa tgcttgacca agttatagaa acctttaata
     1201 taaatgtaga ctatgatttg gatataatgg aaaaaggaca aagcctgaat gatataacat
     1261 gtaagatttt aaataaactt cccttgattt taaacaagga aaatccaaat ataatattgg
     1321 tacatggaga tacaaccaca actctagcta caagtttgac tgcattttat aataaaactc
     1381 ttgttggtca tatagaagct gggcttagaa cctatgataa atattctcct tttccagagg
     1441 agctaaatag acaacttaca ggtattattg ctgatatgca ctttgctcct actaatttgg
     1501 ctagaaaaaa cttgatttct gaaggaaaac ctaataataa tatatttgta actggtaata
     1561 ctgctattga tgctttaaag atgacaataa aagaaaacta taatcatcct ataattgatg
     1621 agattggtaa cgataggatg attttgttaa cctctcacag aagagaaaat ttgggtaaac
     1681 ctatgaaaaa tatattcaga gctataaagc gaatagtaga tgactttgaa gatgtacaga
     1741 tagtatatcc catacattta aatcctaaaa tacgaactat agctgatgag atatttggaa
     1801 aatttcctga aaaaattcat attatagagc ctttagatgt agctgatttt cataactttt
     1861 taaataaatc ttatatgata atgactgata gtggaggaat acaggaagaa gctccatcat
     1921 taggtaagcc agttcttgtg ttgcgtgata aaacagaaag aacagaagga attgaagcaa
     1981 agacacttaa attagtaggt actaatgaag atagaatata taattcagtg agcgatttat
     2041 taataaataa agataactat gttcagatga gtaaagcatc taatccatat ggagatggaa
     2101 atgcaagcaa atatatagtg gatataataa ttaaaaaatt taattgcaaa tatttaaatt
     2161 agataaggcc taaaacatta actaattgat ataagattta tgataatatt aaggaataca
     2221 atttttaagg gggagtaata tggctagaaa attaataaaa aatttgggta aaagtaaaag
     2281 tgtaaagaga gtgaaacttt tatttaagaa gatttttatt actgtattca tagtagcaag
     2341 tatagttgct atttttaata taacgaaata ttttgaggaa ttatacaaag taagggattt
     2401 aaaaagtact aaaattgaat actatatgga tgtggctgat gaagcaggag atggaaaggt
     2461 ccaattaagt tggaaggcct tacttgctat agacatggta atacatgatg aagatttaag
     2521 taatataaaa aagaaagaca cattggatat aggggaaaag tttatagtag aagataaaaa
     2581 tggtaaaggc gaaaaggtgt ataaggtaaa aaagtttaat aaggtattaa gcgaattgaa
     2641 atttgactct tctcaaaaaa gtagagcaag aaaatacatg aaagatttag aatacacata
     2701 ccttggaaat aaacaattag atagtagtga tgaaaaaatt aaatttataa agaagttaga
     2761 agactcagct ataagagaat atattgatta tggaatattg ccctctataa caattggaca
     2821 agctatatta gaatctggtt ggggaaattc taaacttaca aaacagagta ataatttatt
     2881 tggtataaaa gcagataaag catggaaagg aaaaagtgta gaaatttcaa cttcagagca
     2941 ttataatgaa aaaattgtag ctagttttag gtcgtataat tcattacaag attctgtcaa
     3001 agaccacagt ttatttttaa ttaataataa aagatataga aaacatgggt tgtttgaggc
     3061 aaaagattat attagtcaag ctcaagcatt agaaaatgca ggatatagta cagcagaaga
     3121 taaaaaagga aatcgtatat atgcagagct attaatagat gttattagga gttataattt
     3181 gcaattgata gataataaag ttgagacaaa ataattgtta actttatatg aggagataac
     3241 aagataagat ttttttctac aaaaagaata gaaaaattgt aaaaaaaact aaaaaaatgt
     3301 attgacttgt tatttaaaag gtgatattat tattactgta ctcgaaagag aacaaaa
//
LOCUS       DAEHWO010000164         3307 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEHWO010000164 DAEHWO010000000
VERSION     DAEHWO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3307
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.167"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            696..941
                     /locus_tag="KNP54_003899"
     CDS             696..941
                     /locus_tag="KNP54_003899"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894746.1"
                     /translation="MKRIKKVFRDLVENYKEEKFEKQEAIEMQEAIEAIRQEIGRHDP
                     TINTPKDSAGNVGDEPPFISNPLVANQPIKNPKYKGN"
     gene            1380..3221
                     /gene="ltrA"
                     /locus_tag="KNP54_003900"
     CDS             1380..3221
                     /gene="ltrA"
                     /locus_tag="KNP54_003900"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011989152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBF0894747.1"
                     /translation="MYNTDTKSIIKQDLQPLKKDKLRYNEYYNLQNTFDNLYKQSLEG
                     SKFTKLFNLISSEENILLAYRNVKTNTGSKTAGTNRHNINYWKTKDTKIFVQYIQNRL
                     MNYKPQKVRRVEIPKPNGKMRPLGIPCIEDRIIQQCIKQVLEPICEAKFHPHSYGFRP
                     NRGTEHALAYVVKKINFEHMYTVIDIDIKSFFDNVKHSKLLKQLWSIGIHDKKLLSII
                     SSMLKAEIDKVGIPNKGVPQGGILSPLLSNIVLNELDWWISNQWQTHKTHYQYSTTSH
                     LYRALRKTNLKEMYIVRYADDFKIMCKNVSEANRIFIATQKWLKERLGLEISQEKSKI
                     TDVRYSNSEFLGFKIKAYKKRNKYIVYTKMTDKAKEQVSHNIKEQLIAIQHFPTTKNI
                     NMLNRIIAGSHNYYKIVANVYQDFKNIKYNLSFSLYNRLKNLRTSTGNLTHEYESKYS
                     KYNLKKQYILNEIMYPLTGIKTTPPFLFNQTVSNYTKEGRKIIHTRLGCIDNNILNYI
                     AHNPILNKSVEYNDNRLSKYSAQKGTCIISGYPLVENMEAHHITPVNKGGDDKFRNLI
                     LVIPEIHKLIHATNIEHIQYYIKELNLDNQEIKKLNKYRKKIGNEII"
BASE COUNT         1382 a          456 c          552 g          917 t
ORIGIN      
        1 aaaagattag ccaataatga tttattaatt attgaactga taccttgaac tgtcgaatga
       61 tagagtaacg tcttgaaagg cagtcgctga tacttcgaat agcgttcaat tgattgggaa
      121 ttgaaggtta taagctcgat aaagacagct gagagtgtac cctaaggctc tatatgattc
      181 gctatgtcat gtgactaggt tctacaggtc tgaaccttac ttatagaatc tatagagaaa
      241 caggaaatgt aactagaggt agttaagtac atgataggct gggcgtctat aaaatagtca
      301 tggttagaat agtaggtaaa aactactgac gaatctccga atgtacggct ctaaacacaa
      361 acattataga aatgtaatgg gacttaaaca gtagaccttg aagtagagta aaatttgttg
      421 atatgaaata ctttataatg ttaaaggcat tatcaagagg tcagggtcag aggagaaacc
      481 taaaactata tggtaaaaga taaaggtatt ggaacttggg aagggagcaa cgctgagata
      541 agcctaatac aaagtcaatg aagcgttcag aaggaaattt agaatatttt gatgtaatat
      601 attgacaaat tttggtaaat atgttaatct atccttaagt ataaaatgct ttaatgggtt
      661 ttttatgcaa aaatataata aggaaggtta aagccatgaa acgaataaag aaagttttta
      721 gagatttagt ggaaaattac aaagaggaaa agtttgagaa acaagaggct attgagatgc
      781 aggaagctat agaagcaata aggcaagaaa ttggtaggca tgacccaaca ataaatactc
      841 caaaggattc agcaggaaat gttggagatg aaccaccctt catctccaac ccgttggtcg
      901 ctaaccaacc cataaagaat cccaaatata aaggtaatta acctttatat taatagttaa
      961 atctttgtaa tagtacatag ggaaaaaaat agagaaaata ttaaatattt tctctaaacc
     1021 ctaactaaaa aaaaaaggaa acaaacacat aattctcaaa aacttacttt taatatatat
     1081 tacaaaacat tatataaaga atacacacta tataatgcta aagcatatta aggaggatga
     1141 gttctctatc ctccttatac aacatcaaaa tatgtacaaa tctaatataa cttctgttaa
     1201 tgtctcctga aagcgaagcc atagtaccgt tgaagccatg ataataagtg gtggagggat
     1261 gggctttagc caacaatcta aaaattatct attatttcaa attacattag ggttcgagta
     1321 cgattaagaa agattatatt ccttataaat atatacaaag gagataatcg acctatacga
     1381 tgtataatac agatacgaag tcaataatta aacaggattt acaaccatta aagaaagaca
     1441 aactaagata taatgaatat tataacttgc aaaatacatt cgacaatttg tataaacaaa
     1501 gccttgaagg aagtaagttc accaaattat ttaatttaat atctagtgaa gaaaatatat
     1561 tactagctta tagaaacgtt aaaactaata caggaagtaa aacagcaggt acaaatagac
     1621 acaatataaa ttactggaaa acgaaagata ctaaaatatt tgtccagtat atacaaaaca
     1681 ggttaatgaa ttacaaacct caaaaagtta gacgagttga aattccaaaa cctaatggga
     1741 aaatgagacc tcttggaata ccctgtatag aagatagaat aattcagcaa tgtataaagc
     1801 aagttctaga accaatatgt gaagcaaaat ttcatccaca tagttatggt tttagaccta
     1861 atcgtggtac ggaacacgct ttagcatatg tagttaagaa aattaacttt gaacatatgt
     1921 atactgttat agacattgac attaaaagtt tctttgataa tgttaagcat agcaaattat
     1981 taaaacaact ttggtcaatc ggtatacacg ataagaaact cctaagtatt atcagttcaa
     2041 tgttaaaagc tgaaatcgac aaagttggga ttcctaacaa aggagtccca cagggtggaa
     2101 tactttctcc cctactatca aatatagttt taaacgaatt agactggtgg ataagcaacc
     2161 aatggcaaac acataaaact cattatcaat actctactac aagccattta tacagagcat
     2221 tgagaaaaac taacttaaaa gaaatgtata tagttagata tgcagatgat tttaaaatta
     2281 tgtgtaaaaa tgttagcgaa gctaatcgaa tttttatagc tacacaaaaa tggttaaaag
     2341 aaagattagg attagagata agccaagaaa aatccaaaat cacagatgtt agatattcta
     2401 actcagagtt tttaggattc aaaatcaaag cttataaaaa gcgaaataaa tatattgttt
     2461 atacaaaaat gactgacaaa gctaaagagc aagtcagtca caatataaaa gaacaattaa
     2521 tagctataca gcattttcca acaactaaga atatcaatat gttgaataga attattgctg
     2581 gttctcataa ctattataaa atagtagcga atgtatatca agactttaag aacattaaat
     2641 ataatctttc tttcagttta tataatcgct tgaaaaatct aagaacttct acaggaaatt
     2701 taacgcatga atatgaaagt aaatatagta aatataactt aaagaagcaa tatatactaa
     2761 atgaaatcat gtatcctcta actggaatca aaacgacccc accgtttcta tttaaccaaa
     2821 cggtatcaaa ttatacgaaa gaaggtcgga aaataataca tacaaggtta ggttgtatag
     2881 ataataatat actaaactat atagcacata accctatact taataaaagt gtagaatata
     2941 atgacaatag gttatcaaaa tattcagcac agaaaggaac atgtattata agtggttatc
     3001 cattagtaga aaatatggaa gcacaccaca tcacaccagt caacaaagga ggtgatgata
     3061 aatttaggaa tttgatttta gttataccag aaatacataa acttattcat gcaactaata
     3121 ttgaacacat acaatattat ataaaggaac taaacttaga caatcaagaa attaagaaat
     3181 tgaataaata tcgtaagaaa atcggaaatg aaataatatg attgatagat tcttggggga
     3241 acgccgtatg aggtgaaagt ctcacgtacg gtgtggagca ggggaaaaga cggagatagc
     3301 atcaaac
//
LOCUS       DAEHWO010000165         3039 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEHWO010000165 DAEHWO010000000
VERSION     DAEHWO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3039
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.168"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(948..1499)
                     /locus_tag="KNP54_003901"
     CDS             complement(948..1499)
                     /locus_tag="KNP54_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894748.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1690..2652
                     /locus_tag="KNP54_003902"
                     /pseudo
     CDS             1690..2652
                     /locus_tag="KNP54_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
BASE COUNT         1198 a          304 c          471 g         1066 t
ORIGIN      
        1 aaaataaaaa ttaaaaaata tttaatgcta ctacaatagg aactagaact acacttaata
       61 aatatacaga aattagattt ggctcaatat aaaatacaaa tatagaattt aggtgttttt
      121 tatgaaaaaa tttttatatg ctttatatag tttcattgtt attatagcta attttagatt
      181 aaaagaaaaa aattataact ttattttatt agcaatcttt tttatattgc tgttaattca
      241 aaatggagtt ttaaaaacag gttatcaaaa tagagctaca ttttatcaag ataattattt
      301 taatagagag gataaaaatg ataagataaa atttatgact ataaagattt ttatattttt
      361 gtcattacca ttatgtttta atatactatt caattattta acctcttaaa ttatatttag
      421 atataggagt cttatgataa aagtaagctt atgtgttatt tgtagtaaat ataaagtgca
      481 tatagtgata aaacaaaagt ttcatataaa tgaagaaaaa aatataaaat aatttattta
      541 actacttaaa aataaactaa aagggataat aaaatagctt ttaggttatg gtaataaagg
      601 tatttaaaaa gagtgcataa gcactccaat tgtgagaaat acatacacaa atcattatta
      661 caacaatgaa aaatgtacat ataagagacg ttttgtattt gttttaagtg ataatatttt
      721 aatactaact aaataattat cacaatagta aaaaagaaaa aggagtattt tgtactccat
      781 ttgtcaaaaa tataaaactt ttatataagc ttattataac ataattgata aaagtgtaaa
      841 gatatataat gaatttataa agaaaaataa aataaaaaag ataaatccta atcaaaggat
      901 ttatcttttt gtatagaaaa taattattct attattaaat ggcatggcta aactggataa
      961 taatttatta ttactgcttt caatgttttt tctccttgat tatggtatgt atgaattgat
     1021 tcagctgaaa aacaaataga gtcattttct ctaagttgat aaatagagtc atttacttct
     1081 aattttaatt gaccttctat aatcataata tattcctgtg atttttcaga atgaccaaca
     1141 gatgtataac tatgaccttc ttctaattcc atttgaaata attcgaagtt tctagttggt
     1201 gtattgggat aataacaata aagacgataa tctttatttt ctgaaacttg tacatctata
     1261 tcagtttttg atacaataaa agtttcattt tgaggttgtt ccagtattgc agtatatgga
     1321 acatttagtc cacttgcaat tttccaaatt gtgtttactg ttgggtttga gtctcccttt
     1381 tcaatttgcg aaagcattac tttacttacg ccagataatt cagcaagttg acctagactt
     1441 aagttacgtt cattacgtaa tctatttaaa tttttagcaa taacagtatt aatactcata
     1501 gtagctcctt aaaatgtaaa ttattgacaa atataattta cgaatgtata atttatttaa
     1561 cattatttat aatttacaaa tgtataatat aatgaacgtt aaatacactg tacatccgta
     1621 atataaatta tactgcataa agagttgttt ttcaacggat gatagttgag agattaaggg
     1681 ggaattgtaa tgcgtgtact taataatgtt acagaggcta taggcaatac tcatatgtta
     1741 catttatcca aaatagcaga tgaatttgga gttcaaggta atatttatgc aaagatggaa
     1801 tacttaaatc cgggatttag taaaaaggac cgtgtagcat tacaaatgat taccgaagca
     1861 gaaaatgcag gtttattagt tccaggtcaa gcagttgtgg aattaacaag tggtaatact
     1921 ggaacaggac tagcaatagc ttgtgcatgt aaaggatata aatttatagc gtgtatgtca
     1981 aaaggaaatt ctatggaaag agcaagaatg atgaaagctt taggtgctga agtagttctt
     2041 gtagaccaaa tgcctaattc agttcatgga caggtatctg gtgaagattt ggcacttgta
     2101 gaaattgagg ctcaaaaaat agcaaaagaa agaaatgcat ttagagcaga ccaatttaat
     2161 ttagaagctt gtaatcatgc acatgaaaag tatacagcag aagaaatgtg ggaataattg
     2221 gatggaaata ttgatgtatt tgtagatttt cttggaagtg gtagtacttt tgcaggatgt
     2281 tcaaaaacac ttaaaaaaca taattcttct atcaaatgtt atgttgttga acctgaaaca
     2341 gcagcaattt attcaggtaa agaaataact gaccaagggc ataaaataca aggtggagga
     2401 tattctatgg atttgccatt agtagacaag aaacttattg atggttatat tcaagttaca
     2461 gacgaggagg caactgatgt agcaagaaaa ttagctaaat tagaaggtgt atttgcagga
     2521 ttttcttcag gggcaaatgt atgtgcagca attaagttgt taaagagcag tgaaaaagga
     2581 aaaaatatag ttttaactct taatgatagt ggtttaaaat atttaagtac tgatttatat
     2641 gaagaattgt aataatagca caatagttat gcaatgtttt ttaaattaag tatatagatt
     2701 taaattataa aaagtatctc aatgtaattt ttgaaagtta taaaggagat acttttttat
     2761 tttgtaaata tggagtatcc tacttataag tattaagcta tatagatatt gatgattagc
     2821 tatgcaataa aaaagagtat gtgtttttgc atttatacat cataacttgg aataatacat
     2881 attaatgttc taaatgtatt taaaacatat gataaaatta gaacaaatag atacaaggag
     2941 ataaaaatgc aaaagagaat tttaagaaat tttatattta cgggtaaaaa tattttaagt
     3001 aaacttgttt ttataataaa atataatttt agtacatta
//
LOCUS       DAEHWO010000166         2936 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEHWO010000166 DAEHWO010000000
VERSION     DAEHWO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2936
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.169"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..1636
                     /locus_tag="KNP54_003903"
     CDS             <1..1636
                     /locus_tag="KNP54_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBF0894749.1"
                     /translation="FIKVLTNPMSIVLIILSVIILAFYAFFEFTSVIICFNKSIKYEK
                     IGLFELFKISFKNSIKLLYPKNILLFIFVILIIPLVNTVLISGFIGKIQIPEYILDYI
                     KSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESVNLIKGKIIRTII
                     YSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCIAFEEYFRLILSI
                     FIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILLISYIESVAFSSH
                     INGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEIDVQETKDGELIV
                     LHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKY
                     SKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKTILQKVKKLDENL
                     LTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKM
                     LDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            1958..2542
                     /locus_tag="KNP54_003904"
     CDS             1958..2542
                     /locus_tag="KNP54_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBF0894750.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKGLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         1144 a          279 c          447 g         1066 t
ORIGIN      
        1 ttttataaaa gttttgacca atcccatgtc aatagttctg ataatactat cagttataat
       61 actagctttt tatgcatttt ttgaatttac ctctgtaatt atttgtttta ataaatcgat
      121 aaaatatgaa aaaatagggt tatttgaact ctttaaaata tcatttaaga actctataaa
      181 attgttatat cctaaaaata tactattatt tatatttgtg atattaataa ttccattagt
      241 aaatacagtt ttaatttcag ggtttatagg aaaaatacaa ataccagagt acatactaga
      301 ttatataaag tctgatataa ttttaaatat aatctatatg atttttcttt taataatata
      361 tatttcggtt attagatgga tttttagcat tcatgagata actttaaata cagaaaattt
      421 taaaagagca agaaaagaaa gtgttaatct tataaaggga aagattataa gaacaattat
      481 ttattcatta atattatctt tagtagtagc tattattgga tatgcgattt atcatagtgg
      541 aattatattt ataggcatat ggactaaata ttgtactgat atggaatttt tgaagaatgt
      601 atttataaat agatgtattg catttgaaga atattttaga ttgattttat caatattcat
      661 ttttatattg gacattggat ttatctcagc aacttattat caatataaag gagtaaatat
      721 ttctaaaaat aatattaaaa aagagaaaaa atctatatca aaaattgttt ttaatttagt
      781 attaatatta ttgatttctt atatagagtc agttgcattt tcttcacata taaatggtat
      841 gtttaatacg tcattttcat tttatacaac agcaattgct catagagcag gagctgaaat
      901 ggctccagag aatactttgg cagcaataga agaagcttca catgctaaag ctgattatgc
      961 agaaatagat gttcaagaaa ctaaagatgg agaacttatt gtacttcatg attcaaactt
     1021 taagagaact acaggagtag ataaaaatgt ttgggatgta aattataatg aagtaaagac
     1081 atatgatgcg ggaagctttt attattatgg aaaaggttat tatgatgaaa agtttgttgg
     1141 ggaaaagata ccaacactca aagaaatgat aaaatattct aaaggtaagg tgaaattatt
     1201 aatagaaata aaacttaatg gacatgaaaa gggagacgta gtaaaaaaag ttgttcagtt
     1261 aattaaagaa aataattttg aaaatcaatg tatagttgca tctatggata aaactatatt
     1321 acaaaaagta aaaaaactgg atgagaattt attgacatgc tattttatgg caattgcata
     1381 tggtgatttt tcaaagttaa attatgttga tatatatgga attgaatcaa cttttgttaa
     1441 taaaacagta gtagaaaaga ttcataaaat gaacaaaaaa atcttcgttt ggactgttaa
     1501 tagtgacagt ttaattgaga aaatgcttga cctaaatgta gatagtatta ttacagataa
     1561 tccatacctt atagagagtg caatttattg gaagaaaaat ggatttatta gtcaagtgtc
     1621 agattattta ttttaaatat tctataattg tattatccag taaaagagat attattaaaa
     1681 tcaataatat ctctttttaa cataaataag gttgttaaat taaggttatt cttataaaaa
     1741 ttgtgcttat cagctataaa caaggaataa aagtgaaaaa attgctctga gattattaca
     1801 gttaaaagag ttttaagatg acagagagat agattgtcaa ctgtatattt aataaatctt
     1861 gttatttatt aaattttata taagtaaaat atataaatta ataaatctta tgctagaata
     1921 tatatgaaaa acaatataaa tttggaggat taaaaacatg acagagcgag aaaaaatgtt
     1981 ggcaggagaa ctttacgatt gtggtgatat tgagttgtta actcaatggc ataaagcaaa
     2041 aggcctagta agagattata accaaacaga ttcctcggat ttggaaaaaa aagaaaaaat
     2101 attaaatgag ttacttggtg gtaagggtaa aaacttatgg attactgcac cgtattatgt
     2161 agattatgga aataatattt attttggaaa taattgtgaa gtcaatatga attgtacgtt
     2221 tttagatgat aataaaatta tcattgggga taatgcacta atcgcaccaa acgtacaaat
     2281 atatactgca tttcatccaa ctaatgctgg tgatagattt ggtaatgcca aagaagatgg
     2341 ttcatttgaa ttttgtaaaa ctcaaacagc tccagttact attggagata atgtttggat
     2401 tggcgggggt gctattatca tgccaggtgt tactattgga gataatgtag ttataggtgc
     2461 aggaagtatt gttacaaaag atattccaag taatatgatt gcatacggaa atccatgccg
     2521 tattattcga gaaaataaat aaagttaaat tttcttgcaa aatctcaaaa aacacctttc
     2581 ttactttata catagggtat tttctaatac tttcacatcc atattcattt gttaaatttt
     2641 tgtggaatgt agtttttatc acttctatct tacatttcca ccattttttt ataaaagtca
     2701 ttcctttata gatttattta taatagtata tattctattt gatgtttgaa taagcactta
     2761 tttttaagta aaatactaac ttttaggtta gtattttgct atagtatgat gattaagtaa
     2821 gaataaaata ctataataca taaagcttaa taaatataat ttttatttta cttagatatt
     2881 ttcttttgat tagcaatcaa aagtagttat aattttttta attaataaga gtaaca
//
LOCUS       DAEHWO010000167         2673 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEHWO010000167 DAEHWO010000000
VERSION     DAEHWO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.170"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            1103..2374
                     /locus_tag="KNP54_003905"
     CDS             1103..2374
                     /locus_tag="KNP54_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBF0894751.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIMLEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
BASE COUNT         1049 a          332 c          345 g          947 t
ORIGIN      
        1 ggtaattatt tactacaaat gataaaaaat aattatattt taaaggataa aatgctgtat
       61 aaattattgg ggtattttac ctatacttgt tacaaattta cataccactt agttaatata
      121 aaacaaattt caaagagatt ggacaacgaa taaaaattgc aatttatata ccatatagtt
      181 aatataaagc atatttgtgt cgatatatag ttctaactaa gtataagatt tacatacctc
      241 atagttaata taaaacacat attttacatg tttgaagatt ttatcagaaa ccctatttac
      301 ataccgcata gttaatataa aactattaat agtgctatgt tgtttatttg cattaacaag
      361 atttacatac cacatagtta atataaaaca tgtttagcag gagttatgat gataaaacac
      421 attatttatt tacataccac ttagttaata taaaacccca aaataaacta agtattttca
      481 gtacttacac acatacaact ctctcaaatt tgcagtgaac catgagtagt gcaattgata
      541 acatttatca tacaccctca atcccttaca ttgcaactgt taaaccctac tttatcaaaa
      601 atatcgctca ctgcaaaatt tatatatttt tattatatca taaaattcaa actataaaat
      661 taaaatggaa taatttatca atttaagaac acctacatat ttgtaaatac ttactatatt
      721 atctattcta atagttcttc ttctagctag aactaatata aaaatcatct ctgaaagatt
      781 aggacatact aatataaaaa taactatgaa tagatatttt cttgttttaa acgatatgga
      841 taaaaaaact tctgaaaata taatcaaagt tctctttaaa taacattcca ttttatgtaa
      901 gtaggcatta tatttttctt aaatgtcact taaatgtcag ttatatataa taatagtaaa
      961 caactgtatt tcactaatat ttgctattat ctaatagtat ttatagttta gatttgatat
     1021 aatacatgtg gtaaaatttt gatttgtaaa acaaaatttt acctacatat attaaaacaa
     1081 atttaaaact aaggagacct atatgttaaa agtactaaaa ggaaatataa tttttacaaa
     1141 aacttcagaa actttcacag tatttgaaaa tagttatatt atgctggaaa aaggtaaagt
     1201 aaagggaata tttaaagaga tacctaagga atacaaaaac ctaaaagtag tagattacac
     1261 tgataagctt ataatacctg gtatgaatga cctccatgcc catgcctctc aatttaaaaa
     1321 tcttggaatg gctatggata aagagctttt gccatggctt gaaacttata catttccaga
     1381 agaatcaaat tataaagata tagaatatgc aacaaaaatg tataaaaaat ttgtaaaaga
     1441 actttggaaa tctggaacta caagaatagc agtgtttgca acagtacata aagaagcctc
     1501 tatgaaactt atggatatat tcaaagaagt tggtcttgga gcatacgttg gtaaagtaaa
     1561 tatgaatatg aattgccctg atactttatt agaaaacact caggattcta ttactgatac
     1621 agaagaaatt ataaataagt atagtgatac agattctatt gtaaaaccaa taataacacc
     1681 tagatttata ccaagctgta caagtgaact tttaaaaggt ttaggagatt tatgtttaaa
     1741 atataatatt cctattcaat cacacttatc tgaaaattat gatgagattg aatgggttag
     1801 aagtctagaa cctgaatcta aattctatgg agatgcatat aatagatata atttatttgg
     1861 tcaaactcct actttaatgg ctcattgtgt tcattgttct caggatgaaa tagatttaat
     1921 gagagaaaat aatgttatgg cagttcactg tccagcttct aactttaatg ttggtagtgg
     1981 tgctatgcct atcagaaaat taatcgataa taatattaga ttagcacttg gatcagatat
     2041 aagtggtgga catacattgt caatatttaa agcaatggta tctgcaatac aattatctaa
     2101 attatattgg gttaactctg gtaagaagta taatttctta tctttatctg aggcttttta
     2161 tattgcaacc aaaagtggtg gaagtttctt tggaaaagtt ggtagctttg aagaaggtta
     2221 tgattttgat gcattgatta ttgatgattc aaatttaaat catgacaatt attctatact
     2281 tgaaagactt gaaagattta tatatgttgg tgatgataga aatatcattc atagatatgt
     2341 atgtggaaaa ctaattgaag aacctaatat ataattataa taaaaatttt aattatatat
     2401 tatggttaat ttatacaact ataattaata aaagagtata ttttaaatct aaaagctata
     2461 ggttgaaaca tactcttttt attttgttta tttatagctt tagttattaa tcatatataa
     2521 atctacaaaa cgtattccta gtaacttaca ttttttgata tctacaatca taagactata
     2581 ttattattgg attcagacct caaaaatatt gccttctgaa cattattata ttcaaagcta
     2641 tgttaattta caatgatata tctaacatgt act
//
LOCUS       DAEHWO010000168         2642 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEHWO010000168 DAEHWO010000000
VERSION     DAEHWO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2642
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.171"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            467..946
                     /locus_tag="KNP54_003906"
     CDS             467..946
                     /locus_tag="KNP54_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0894752.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            943..1722
                     /locus_tag="KNP54_003907"
     CDS             943..1722
                     /locus_tag="KNP54_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894753.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFIPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(1972..2472)
                     /locus_tag="KNP54_003908"
     CDS             complement(1972..2472)
                     /locus_tag="KNP54_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0894754.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
BASE COUNT         1035 a          362 c          318 g          927 t
ORIGIN      
        1 gttcatctct atctaaaata atgacatttc taactcttaa ttctcattta agtttcattg
       61 ttttttctta aaagcctact tttagtcaag atactgttat ctttactcat tatttaaaga
      121 acttatttta aatctgtaca tgaagtaaat aatccaaaag cattgttatt ctaactactc
      181 aacattaaat acttactatt ttctaattac tcaatataaa gacttactat aaaactaaat
      241 acataaatgg cttctaaagt ttaatatatc tacatggctt tatatatgac aggaaaaata
      301 ctagaaaaaa tatattatag aatacttgta tataataggc aaaactttca aacttaaatt
      361 tatcaaataa tcataaaaaa agtgaaccat ctatagtaaa attttatcta ataagtgaaa
      421 ggcaaaaaag tagcgctacg atttgcatag aagggaagga acttagttgg ataaaactac
      481 atttacaaac aatatacttg aatcagaaca gactttgtat cgagtatcta agtctattct
      541 aggaaatgac caagactgtg aagatgccgt caacaatgct attttaaaag catatgaaaa
      601 gttggattct cttaaggaag aacaatactt taaaacatgg ctgattagaa tagtcataaa
      661 tgaatgtaat tcattaagac gcaaacgatt aaaatctcta tcatttgaag atgtcttcaa
      721 aaacaaaaaa attgatgaaa aagatgacta tagcgatttg tatactgcta ttcaaagtct
      781 acctaaaaaa attaaaattc caatagtcct ttactatatt gaaggttatt cagtagatga
      841 agttaaggaa atattagata tacctcaagg aactgtaaaa agtagattat caagaggaag
      901 aagattatta aaaactaaat tagaaaacac agaggtaatc atatgaataa aaatatatta
      961 aataattcgt ttccagaagt tccagaaagt tttcataata gtttaagcaa aacactaaat
     1021 agtttaccag aaagagagga aaattataaa atgattaata ataaaacaca caaattacca
     1081 tttagaaaag gcttagttgc aactttagcc attactttga tattgagcac aacagccctt
     1141 gcagtaggac atatatatag tttagttgga aaatcaagta ctaaggctac ctatacatct
     1201 atcccaacta cagaacaagt aaaaaaagac tttaacttta cccctaatat agtttctgaa
     1261 tttagtaatg gatataaatt taaaggagca tatactgtaa ataaaaaagc atttgacaaa
     1321 gaaaataatg ttttaggaaa atcaaaagca cttagttttg aatataaaaa tggcaatgat
     1381 gaaatatctc ttgacacagc aaataatgta cttgggaaga gttctgacaa tctaaaagtt
     1441 gtagatactt acaaagatat taatatttct tatgaagcat tcgcacaaaa gtttatacca
     1501 gaaggttata aaatgacaga acaggataaa attgatgaaa aatcaggcaa atacacattt
     1561 agtgtggggc caaataatga atcagacaaa gttgaagtta atgaatttaa gtttttgaca
     1621 tggaaacaag atggagttta ctattctttt acagttcaag actcaaattt atctatgaat
     1681 gacttagtta aaatggctca tgaagtaata gatgcaaaat aaacataagt aataataagt
     1741 tgtttatgag tttattattt atgactttaa tttttttatt agtaaacatg gttgtatctt
     1801 ccatctttat attttcttta aatttaatat ataaaatttt agatatttag ctaccttcaa
     1861 aagaagcatt attaaaaagc ccttaaaaat atttctttta tatggaattt taagggcttt
     1921 aactttattt tatacaagtg tatatggaat tttaaagact ttaactttat tttatataag
     1981 tgtaagctcc atttgaatta cttcttcttt tacaggtcta tcattccatg taaaaccact
     2041 agatattgta tttacctcta caaaccctaa agatttataa acatgaatag ctctactatt
     2101 acttttaaat acatcaagct caattttttc atacccatat tcttttgata aatcaataat
     2161 ttgttttaaa agactacttc cgataccttt ttccctatac tctttaagaa tacccatgcc
     2221 taaataacca actttttcag ttttaggtaa aacgtcacac caaccaatac agttatctga
     2281 ttctaaatca attataaaca gttgtggtaa gtttttattt ataatatttt ttataaattc
     2341 aactgtttct tcaaaaggaa aggcttcatc catagctaga tatttcctct cttttgctat
     2401 tttatcaaaa gtttgccaat acgaataaat atacttttct tctgccttta taaattttat
     2461 gccttctatc aacttaacat ttcccctttt taatttttga ttgtagttaa cttattttat
     2521 atgattctag tttataatgc tatataaatt actatatatt agcttaaaat atctttgtat
     2581 atttctataa aattaaaacc aatatatcta tctcttgcat ctctattaaa ataattttta
     2641 at
//
LOCUS       DAEHWO010000169         2605 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEHWO010000169 DAEHWO010000000
VERSION     DAEHWO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2605
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.172"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            262..2280
                     /locus_tag="KNP54_003909"
     CDS             262..2280
                     /locus_tag="KNP54_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBF0894755.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIR
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
BASE COUNT         1076 a          306 c          432 g          791 t
ORIGIN      
        1 ttgtattaaa tttaataaac ctacaattgt tatatgtttt tatttgtctt ttatagattt
       61 ttttggcaat aaatgatata gtgaagataa ttaaatatat tcaatatatt taattttttt
      121 attttttgtt tttataattt ttttagaagt ttatttttta tgtacttatt tataattttg
      181 ggtaaaaaca ctttgatata atttcaaaaa ttaaaaggtt aaaaaacaaa gtagaaattt
      241 atgttaaata aggagattaa tatgagaaga aatacaaaat tattaacaac agggattctt
      301 tcaatggcaa tcgtcgcacc tacaatggca tttgctactg aatctaatgc tatggaaaat
      361 aacgctgatt taaatataaa cttagagaaa aaaagtatcg ttttaggtag tacctcaaaa
      421 gtcagtgtta agtttaaaga aaaaccagat gcagatagca ttacattaaa gtataaatgc
      481 tatgatatgc cattggatac aactttaaac tataatcaat caactgagtc atatgaagga
      541 actatcaatt ataataaaga cccagaatat ctaaatgttt gggaactaca agggataaca
      601 ataaacagca aaaataatcc taaaacttta aacaaacaag aactagaaaa gatgggatta
      661 aatttaaaag actataatgt aacgcaggaa tgtataattg aagatataac ttctagaaaa
      721 gatgtaaata aatatttaag aaaaacttct gcacctatta cagaacttac aggaagtgat
      781 agatacgaaa cagcagttaa aataagtaaa gaaggctgga aaaatggttc agataaggta
      841 gttataataa atggggatgt aagtatagat ggcattatat caactccact agcaactaca
      901 tataatgcgc caatactttt ggttgaaaaa aacaatgtac ctaatagtgt aaaatcagaa
      961 ttaaagcgtt taaatcctag agatgtaatt ataattggag atgagaatgc tatttctaaa
     1021 actactgcta atcaaattaa atcgactgta aatgctagtc aaacacgtct aaagggctct
     1081 aatagatatg agacatcttt attgatagca aaggaaatag ataaaaatca tgatgtggaa
     1141 aaagtataca taacaaatgc taatggcgga gaagtggatg cacttactat agcagcaaaa
     1201 gcaggtcaag acaagcaacc aattatatta actgataaaa atagtattac agacaacaca
     1261 tataaatggt taaagagtga ggatttacaa aatgcttatt ttataggtgg ccctcaaatg
     1321 atatcaacaa atgttataaa taaggtaaat gatataacta aagataatgt tactaataat
     1381 agagtatatg gagcagatag acacgaaaca aatgcaaacg taataaaaaa attctataca
     1441 gatgatgagt tagaggctgt tttagtagct aaatcagatg tacttgttga tgctttagca
     1501 gcaggtccat tggctgcgaa cttaaaatct ccaatactta taacaccaaa gacatatgta
     1561 tctgcatacc ataaagaaaa cttagaagct aaatcggcaa ataaggtata taaaataggt
     1621 ggaggattga cttctaaggt aatgagctct atagcatcat cattatctaa acacaataca
     1681 actccaacag aaccaggaaa tagtgggggc aagacagtta tgattgaccc aggacatggt
     1741 ggttcggaca ctggaacaac aggtaaacca ttagggggta ttagagaaaa agactataca
     1801 ttaaatactt cacttgcgac aactgaatat ttacgttcaa agggattcaa tgtaataatg
     1861 acaagagaca cagataagac tttatctctt ggaaatagaa ctgctttatc taactctttg
     1921 agaccagatt tatttacgag tatacactat aatgcatctg atacaactgg gaatggtgta
     1981 gaagtatttt ataagcttaa agataaagat ggagggacta ctaaaactgt agctacaaat
     2041 atattaaata gaatcttaga gaaatttaat ctaaaaaata gaggtgcaaa aacaagaaca
     2101 ctatcaactg accctacaaa agattattta tatgttttaa gaaataatga tatgccagct
     2161 gtacttgtag aatgtgcatt tttggataat gagaaagata tgagtttact taatacatca
     2221 aataaagtaa aagaaatggg tacacaaata ggtaaaggca tagaagattc attaaaatag
     2281 tctacaatga gagcatagaa aaatttaaaa taaattaatc tgcaatttta aatttaaact
     2341 aaagctataa gataagaatg taattataat agtaataaag actgtatata cattgtgcat
     2401 ataagtgcga aatgaggtat atacagtctt tttatgatta attgtaaaag gatttatatt
     2461 atatgaagaa tttacatatc ttaaggctac agttaattgt caagagttgg agtattcatt
     2521 tgtaatacac aataaaagct taattactat attttattgt gtgtttgtgt gttttttgtg
     2581 gatttttatg tcaataaatg atata
//
LOCUS       DAEHWO010000170         2494 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEHWO010000170 DAEHWO010000000
VERSION     DAEHWO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2494
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.173"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            46..519
                     /locus_tag="KNP54_003910"
     CDS             46..519
                     /locus_tag="KNP54_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBF0894756.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDTAVEQIVDGIRFTPMKLLI"
     gene            complement(888..1445)
                     /locus_tag="KNP54_003911"
     CDS             complement(888..1445)
                     /locus_tag="KNP54_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0894757.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
     gene            1703..2401
                     /locus_tag="KNP54_003912"
     CDS             1703..2401
                     /locus_tag="KNP54_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBF0894758.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT          928 a          322 c          304 g          940 t
ORIGIN      
        1 agatatataa ttataattaa aataataata aaggtgttgt ttataatgtt caaagaatac
       61 ttaataagag aattaaaaga agatgatatt aaaaatgcat tagacttaat ctggaacgta
      121 tttgaagaat ttgaatctcc agattattgt gatgaaggaa ttacgacatt tcatcaattt
      181 atagaatata actctattat tgaaaaaatc aaagaaaaaa ctctcttctt ttggggttgt
      241 tttgactcta aaaaacttat tggagtctta gctattagaa atttaaatca tatatgtatg
      301 ttatttgtag ataaaaacta tcataaacat ggtgttgcaa aaaaattaat gactacaggc
      361 atacaatact gtatttgtaa taaatttaat ttaactgaaa taactgtaaa ttcatcacct
      421 tatgctgttg aagtttatca taaattagga tttaaagata ctgctgttga gcaaattgtt
      481 gacggtatac gttttacacc tatgaaattg ttaatataat aaattaaata aaaagcaaag
      541 tctcttaaat attttatagt tactttgctt ttaaaccaag atttaaaata atactatctt
      601 ttttgttttt taataatata ctttaaaatc cttactaata tgaactataa tttatttttt
      661 gatatccttt ttgattaaca tataaattaa ttcaattatt aaacataaac tatgttgttt
      721 ctctttatat ctcttctttg taaacaatat tgggcatttg aaaataaata ttcttaaaat
      781 atactgttct cctgttgatt ttcctttggt acaaatgata aaaatttaat ttacatgccc
      841 cataatgaag tgttcaataa ataagttaaa ataatttatt tacctcctta atcatatttt
      901 ttatgaatac ctaataacac agtatcaata gaatcggcta aaccttttat agcttcttct
      961 ttactcaaaa gtgatttccc aagttgcaaa gtcgaataac catgaagtac actcattatt
     1021 aagtttaata cttcacctgt attctttgta tttagattac aagaaagaat aagtttttct
     1081 aataaggatt tatattcatc aaagatttct aatgtttcat tatttccatg ccaagtagcc
     1141 cactgaattg tttcataaac accaggatta gaaattataa aattaaagta tgctatactt
     1201 atacacttta tagctgtatc tccaaaattt ccaatagtcg cctttatcat ttgactattc
     1261 atctctctca ttcctttatg agctacttca agtaataaat catctagact ttctatatga
     1321 ttgtacaaag atggtgtacg tattcctagc ttttctgcaa taacttttaa agaaactttg
     1381 ttaagcccat ctttattaac tatatctgat gtagcttgta taactatttc tctactaaca
     1441 cgcatgattt tccctctttc atttaaaatt aattacttta ttagtttagc taatctaatt
     1501 agtttcgtca attattgtaa tttataaaat tctttatact attataaaat cttgacagtt
     1561 taattataat ttaatataat actaattgaa ttagttttaa tactaatata attagtatta
     1621 tattaaattc tatattacaa cattatttta tagtttgatt aatttaacaa tcactaatat
     1681 atcaaactga aaggagattt ttatggaaaa aaaatatttc gaaattcatg gagttccttc
     1741 aatcctttgg ggaaatcctt caagtaaatt atatatttac atacatggac aatgtggcaa
     1801 taaagaggag gctgaagctt ttgctaatat tgcagttcca catgagtgtc aagttttaag
     1861 tgttgatttg cctgaacatg gagaacgtaa aagagaaaaa aattcattta acccatggca
     1921 tgttgttcca gaattagtat ctattatgga atatgcaaag tgccactgga atcaaatttc
     1981 gttatatgca aatagcattg gagcatggtt tagtatgtta agctttgaaa aagagaactt
     2041 aagagagtgt atttttgtat ctccaattct agatatgcaa cagctcattt caaatatgat
     2101 gctttgggca aatgtatcag aagaacagct taaacatgaa ctaattatcc caacttcatt
     2161 tgggcatact ctttcatggg aatatctaca atatgtaaaa caacatccta tcactcaatg
     2221 gaatgtacca acaaaaatat tatatggtaa acatgatgaa cttactgaaa tcggtgttgt
     2281 agagaaattt gtagaaaagt ttaattgcaa ccttactatt atagaaaatg gcaaacattg
     2341 gtttaacaca ccacaagaat taaattcatt atatgaatgg ttaaatactt tagttaaata
     2401 aaaaataatt atattattaa tatgattaaa ttatttataa atgttattta attaatttta
     2461 ttttagcatt attaaaataa ctacataaag aata
//
LOCUS       DAEHWO010000171         2200 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEHWO010000171 DAEHWO010000000
VERSION     DAEHWO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2200
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.174"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(101..2146)
                     /gene="bclA1"
                     /locus_tag="KNP54_003913"
     CDS             complement(101..2146)
                     /gene="bclA1"
                     /locus_tag="KNP54_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBF0894759.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGNTGVTGSIGPTGVTGPTGNTGEIGPTGATGPTGVTGSIGPTGATGPTGEI
                     GPTGATGATGVTGSIGPTGATGPTGATGVTGEIGPTGEIGPTGATGPTGVTGSIGPTG
                     ATGEIGPTGEIGPTGATGPTGVTGSIGPTGATGPTGATGEIGPTGATGPTGNTGVTGE
                     IGPTGATGPTGNTGVTGEIGPTGATGPTGVTGEIGPTGNTGATGSIGPTGVTGPTGAT
                     GSIGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIG
                     NSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTT
                     EPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
BASE COUNT          464 a          530 c          354 g          852 t
ORIGIN      
        1 ttattttatt cattctaaaa taggtaaaac tcaatatata aaaatacttt tgtcatttaa
       61 ataaagccta aatagttttt aagattattt tagacacgtt ttaagtcata acagtatcag
      121 ctattctaaa tatcgtcaaa gtagccgcag ttcctgctga ttgcccattt cgtatcccta
      181 ctgttgtaga tgaaaaatta tttattgtaa aagtagtccc accaaataaa aaaccagcaa
      241 aatatccaga aagtactcct ccgcctcctg gctcagtagt aagccctgcc aaatcttttc
      301 ctcctaaaat tgggaatagg atagcgaaag aatattgatt tatacttgat gaacctggtt
      361 gtaatgctac tgaaactgat atataataca caccattttc ttgtactgta aacgtaccat
      421 ttgcatctac tgttatactt gaactatttc ctattattgt ttgccaacct gttatagcat
      481 ctccattatt tagtgtttgt ggagatggtg catttacgag gaagttagca actggctgag
      541 aggaattgcc tgttgctcct gttggacctg ttgggcctgt tactcctgtc gctcctgttg
      601 ctcccgttgg tcctatactt cctgtcgctc ctgttggacc tgttactccc gttggcccta
      661 tacttcctgt cgctcctgta tttcctgttg gccctatttc tcctgtcact cctgttgggc
      721 ctgttgctcc cgttggtcct atttctcctg tcactcctgt atttcctgtc ggacccgttg
      781 ctcccgttgg tcctatttct cctgttactc ctgtatttcc tgttggacct gttgctcccg
      841 ttggtcctat ttctcctgtc gctcctgttg ggcctgttgc tcccgttggt cctatacttc
      901 ctgtcactcc tgttgggcct gttgctcctg ttggtcctat ttctcctgtt ggtcctattt
      961 ctcctgtcgc tcccgttggt cctatacttc ctgtcactcc tgttgggcct gttgctcccg
     1021 ttggtcctat ttctcctgtt ggccctattt ctcctgtcac tcctgtcgct cctgttggac
     1081 ctgttgctcc tgttggtcct atacttcctg tcactcctgt cgctcctgtt gctcccgttg
     1141 gtcctatttc tcctgttggt cctgttgctc ctgttggtcc tatacttcct gtcactcctg
     1201 ttggacctgt tgctcccgtt ggtcctattt ctcctgtatt tcctgttggg cctgttactc
     1261 ctgttggtcc tatacttcct gtcactcccg tatttcctgt cgggcctgtt gctcccgttg
     1321 gtcctatact tcctgtcact cccgtatttc ctgtcggacc tgttactcct gttggtccta
     1381 tacttcctgt cgctcctgta cttccggttg ggcctgttac tcccgttggc cctatacttc
     1441 ctgttgctcc tgtatttccg gttgggcctg ttggtcctat gcttcctgtc gctcctgtac
     1501 ttccggttgg gcctgttact cccgttggtc ctgtacttcc tgtcgctcct cttggtccca
     1561 ttggacctgt aattctaatt ggaagacact cacatttagg ataacaatta tctataattc
     1621 tatcttcaaa tgttacaagt atatacggtt tgttacaacc tctactagat gtaaattcaa
     1681 gaatctgata agggtaattt aaagataaag ctaacccata attaggatat ttattcattg
     1741 cccatgcttt tatagttccc gtaatattta aacaaatata gttggatgta tcacttatcc
     1801 caactggtaa atatccccta atattttcca tagacactct atcattccat gttatagttc
     1861 gtaaattata atattcactt attcttttaa tttcaatatc tactttttct ttaaaaatat
     1921 gattcttatt tgaatcaata tgaataaata actctgcttt taatatactt ttgtctttta
     1981 atatatctgg tattctcact ttaaaaaaag taatcaactt ttcttttaca aaactatttg
     2041 aacatttact tcctattaag caataatcta aattactaaa gtttttatct ggatattttt
     2101 tagatataaa agtatcatca tttaaataaa gtataatatt tctcatttat aatccctcca
     2161 ttttgggtct atatcatact atgtttaaaa tacatgctta
//
LOCUS       DAEHWO010000172         1965 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEHWO010000172 DAEHWO010000000
VERSION     DAEHWO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1965
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.175"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     misc_binding    781..1044
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1195..1746
                     /locus_tag="KNP54_003914"
     CDS             1195..1746
                     /locus_tag="KNP54_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBF0894760.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          824 a          191 c          284 g          666 t
ORIGIN      
        1 agcattataa atccattaca agtagaagca gaagctatta ttgagtctag tgtatacatt
       61 tcttcaataa aagagaatta tacatatgat aatactaaat ttaaaactat taaatctaaa
      121 agtagacata aaagtaggaa atataataaa agtaaagtaa agttgaaaaa acgaagtata
      181 agaactaaaa agtatggata tcaaactata aataaatata aaagacaaaa cgcaagaaga
      241 cataatatcc taacaaaatt aatattgtcc ataatagtca tatttttggt tatagtttta
      301 gtagtgctaa tatttattaa aagaaagaag aaaaaatttt actaaaaata attaaaagaa
      361 tatcattttt ttaatcattg gtatctattt aataatatga tgtaattaaa atggagtaat
      421 attctgtttc aaaggaggca tataaataca ggaatgagta ttaaatgatg gttaattaag
      481 taaatttatt gataaatgta cttaattaac tttgaagaat ttaattcctc atgaatcaaa
      541 atataaaatt acatcaacag ttattcacaa aattaatata agaagaatta gagccaaaga
      601 gcagactatt agaccattaa agtaattatt catagaattt tgtatatgaa aagaaatgta
      661 tagtataatt tacttttttt ataaaaaata gattacaaaa tatatttttt ataaaaaggt
      721 attgacattt tttagaaaaa agaatatcat tattttaaca acaaaattca atacaataaa
      781 ttaaatccta tgacaaggaa gagtagttaa atttaggttc agtatagaga gctgaggatg
      841 gtggaatctt agcaagaaaa aatttgatga atggccctta gaggaataaa ttgaaatcat
      901 agttttgaga gtagacttta tcgtcagtcg cacgttatag cgaataaggt atgtaagtac
      961 ctgataatga gatgtatgaa aattgaattt tatattaatt tttatataat ttaggtggca
     1021 acgcggataa tctccgtcct attagtttag gacggagttt tttattttac tgaaaattta
     1081 aaagatagaa ggtggtgaga aagatgttat gaatttcaaa agctaaagat gatgatatag
     1141 taggttggca aaaaaataaa ttgaaaatta aaaaaatagg aggaagtaca aaaaatgaaa
     1201 acaaatacaa aaaaattaac tttaaatgca atacttttag cgatgggatt attaatacat
     1261 caaatcacac cagctatagg attaccaatg aagccagatg taccactagc aatgttattt
     1321 gtaatattgg ttttaaatag agatgattat aaaacttgtt tgatagcggg tatagtaaca
     1381 ggaatattta cagcacttac atcaagtttt ccgggaggtc aaattcctaa tgtaatagat
     1441 aaaactctta cagcaaatat agtattttta ttaatgaata ttagttataa tatgcctttt
     1501 ataaaaaaat tagctaagaa aacacaagat actgtagtag ttgcaataat aatgccaata
     1561 ggaactcttg taagtggaac tatcttttta ttagcagctc aagctatagt tggtcttcca
     1621 ggggcttcat ttacagcttt attcttagca gtagtattac cagctgtttt aataaatcta
     1681 gttgcaggaa tatttttatt caagattgtt agtctatcaa taagaagagt tagttatcaa
     1741 gcttaaacac gaaataatat tttactttat aaagcattat aataactaaa taacataaga
     1801 ataaagtaga ttataactat tttattctta tgttgtttaa agatttggta ttatatattt
     1861 atttttaata aaatatttat atagtaccaa ttacacttaa tttaacagat aaattatcat
     1921 acctatataa tattcttata tgtatctcat ttgtagttat taaat
//
LOCUS       DAEHWO010000173         1925 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEHWO010000173 DAEHWO010000000
VERSION     DAEHWO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.176"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            119..235
                     /gene="rrf"
                     /locus_tag="KNP54_003915"
     rRNA            119..235
                     /gene="rrf"
                     /locus_tag="KNP54_003915"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            242..316
                     /locus_tag="KNP54_003916"
     tRNA            242..316
                     /locus_tag="KNP54_003916"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:274..276,aa:Asn,seq:gtt)
     gene            321..395
                     /locus_tag="KNP54_003917"
     tRNA            321..395
                     /locus_tag="KNP54_003917"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:354..356,aa:Glu,seq:ttc)
     gene            401..476
                     /locus_tag="KNP54_003918"
     tRNA            401..476
                     /locus_tag="KNP54_003918"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:434..436,aa:Val,seq:tac)
     gene            482..558
                     /locus_tag="KNP54_003919"
     tRNA            482..558
                     /locus_tag="KNP54_003919"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:516..518,aa:Asp,seq:gtc)
     gene            569..643
                     /locus_tag="KNP54_003920"
     tRNA            569..643
                     /locus_tag="KNP54_003920"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:601..603,aa:Thr,seq:tgt)
     gene            658..742
                     /locus_tag="KNP54_003921"
     tRNA            658..742
                     /locus_tag="KNP54_003921"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:692..694,aa:Tyr,seq:gta)
     gene            752..825
                     /locus_tag="KNP54_003922"
     tRNA            752..825
                     /locus_tag="KNP54_003922"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:784..786,aa:Gly,seq:tcc)
     gene            836..912
                     /locus_tag="KNP54_003923"
     tRNA            836..912
                     /locus_tag="KNP54_003923"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Arg,seq:tct)
     gene            922..997
                     /locus_tag="KNP54_003924"
     tRNA            922..997
                     /locus_tag="KNP54_003924"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:955..957,aa:Gln,seq:ttg)
     gene            1009..1084
                     /locus_tag="KNP54_003925"
     tRNA            1009..1084
                     /locus_tag="KNP54_003925"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1042..1044,aa:Lys,seq:ttt)
     gene            1087..1175
                     /locus_tag="KNP54_003926"
     tRNA            1087..1175
                     /locus_tag="KNP54_003926"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1121..1123,aa:Ser,seq:tga)
     gene            1193..1283
                     /locus_tag="KNP54_003927"
     tRNA            1193..1283
                     /locus_tag="KNP54_003927"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1227..1229,aa:Ser,seq:gct)
     gene            1292..1368
                     /locus_tag="KNP54_003928"
     tRNA            1292..1368
                     /locus_tag="KNP54_003928"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1326..1328,aa:Pro,seq:tgg)
     gene            1454..1529
                     /locus_tag="KNP54_003929"
     tRNA            1454..1529
                     /locus_tag="KNP54_003929"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1487..1489,aa:Trp,seq:cca)
     gene            1590..1666
                     /locus_tag="KNP54_003930"
     tRNA            1590..1666
                     /locus_tag="KNP54_003930"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1624..1626,aa:Pro,seq:tgg)
     gene            1673..1749
                     /locus_tag="KNP54_003931"
     tRNA            1673..1749
                     /locus_tag="KNP54_003931"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1707..1709,aa:Ile,seq:gat)
     gene            1753..1828
                     /locus_tag="KNP54_003932"
     tRNA            1753..1828
                     /locus_tag="KNP54_003932"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1786..1788,aa:Phe,seq:gaa)
     gene            1836..1912
                     /locus_tag="KNP54_003933"
     tRNA            1836..1912
                     /locus_tag="KNP54_003933"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1870..1872,aa:Met,seq:cat)
BASE COUNT          484 a          442 c          524 g          475 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgttaactc taaaaaaaaa taaaaaaagt
       61 attgacaaaa atagtaaaaa atgttaatat tatacttgtc ctagcaacaa gaaaaaaatg
      121 tggttataat agcggagaag atacacctgt ttccattccg aacacagaag ttaagttctc
      181 tagcgctgat ggtacttggt gggaaactgc ctgggagagt aggacatagc cacgtgaatg
      241 ttccaaggta gctcaacggt ggagcaaccg gctgttaacc ggtaggctgt gggttcgagc
      301 cccacccttg gagccattat ggctcgttgg tcaagaggtt aagacaccgc cctttcacgg
      361 cggtaacagg ggttcaattc ccctacgagt caccatttgt gggatcatag ctcagctggg
      421 agagcacctg ccttacaagc agggggtcac aggttcgagc cctgttggtc ccaccatttg
      481 cggcctggta gttcagttgg ttagaatgcc agcctgtcac gctggaggtc gagggttcga
      541 gccccttcca ggtcgccaaa ataaaaatgc tggtgtggct caacggtaga gcagctgact
      601 tgtaatcagc aggttgtagg ttcgattcct atcaccagct ccatgtaaaa ctaatacgga
      661 ggatttcccg agcggccaaa gggggcagac tgtaaatctg ttgtcatcga cttcggtggt
      721 tcgaatccac catcctccac caattaaata tgcgggtgta gctcaatggt agagttctgg
      781 ccttccaagc cagctgtgag ggttcgatcc ccttcacccg ctccaaagaa agcgtgggtg
      841 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      901 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      961 catgtatgcg taggttcgag tcctgcatcc ccagccaaat aaaaatatgg tctattagct
     1021 cagtcggtag agcacctgac ttttaatcag ggtgtcccgc gttcgagtcg cggatagatc
     1081 accaatggag aggtgtccga gtggtttaag gagctggtct tgaaaaccag tgacttcgaa
     1141 aggggccgtg ggttcgaatc ccaccctctc cgccaaaaaa atgactgaat ttggagaagt
     1201 actcaagtgg ctcaagagga tcccctgcta agggattagg ctgggtaacc ggtgcgaggg
     1261 ttcgaatccc tccttctccg ccattcaaaa acgaggtgta gcgcagtttg gtagcgcaca
     1321 tggtttggga ccatggggcc gggggttcga gtcccttcac ctcgaccaac ttaagctttt
     1381 agttcagttg gttagagtgc ccaactcatg gctagtaatt ctagggtttg agtccatgaa
     1441 ggttattctt cataggggtg tagctcagtt ggtagagcgt cggtctccaa aaccgtgcgc
     1501 cgggggttcg agtccctcca cccctgccaa ataaaaagga cttgaaaaaa gttggatttt
     1561 agagtagtat aagatagtaa ataagatttc gaggtgtagc gcagtttggt agcgcacatg
     1621 gtttgggacc atggggccgg gggttcgagt cccttcacct cgaccaagaa aagggcctat
     1681 agctcaggtg gttagagcgc acgcctgata agcgtgaggt cgctggttcg agtccagcta
     1741 ggcccaccat ttgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc
     1801 ggtggttcga ttccgcctct gggcaccagg aatacggcgg tatagcttag ttggctagag
     1861 cgttcggttc atacccgaaa ggtcataggt tcgactccta ttaccgctac catctaacta
     1921 tatca
//
LOCUS       DAEHWO010000174         1919 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEHWO010000174 DAEHWO010000000
VERSION     DAEHWO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.177"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            342..1670
                     /locus_tag="KNP54_003934"
     CDS             342..1670
                     /locus_tag="KNP54_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBF0894761.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIIIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
BASE COUNT          669 a          213 c          339 g          698 t
ORIGIN      
        1 cagaaagaag ccaaaatgtt tttgaaaaaa atgaaatttt attgcaaaaa aatcaaaatg
       61 aatttaactt aatagttata atctattttt agtgttacaa atatacaatg tatattatac
      121 aatataaaaa atacatttac ttagaagtat tattatattt ggatttttgg tttttataat
      181 ttttttatat ttaaacataa ctaaaaataa aagattacta aagctaagta gagtttattt
      241 tattttaata aataataaag ctatttttct atatattggc ataatatatg cttatttaac
      301 tatgaaatta aaattaaata ggattaatga ggaggaaaaa aatgggaagt aatgaactga
      361 aaaagactct tggcgtatca gcagcattat caactgttgt tggttccgtt ataggagcgg
      421 gcgtattttt taaaccacaa gcagtctata cattaactgg aggagctcca ggtcttggta
      481 tattggcatg gttaatagct ggaatcataa ctataacagc tggtcttaca gctgcagagg
      541 tatcagttgc gataccaaaa actggtggaa tgatggtata tataaaagaa atttatggag
      601 aaaaattagg ttttttaact ggatggatgc aaattgtatt attttatcca gggatgatgg
      661 cagcattagg tgttatattt ggagaacaag catcggcact aattggtagt ccatcacttt
      721 tacttccaat agcaattgga attataataa tagttgcagg gcttaatatg ttaggttcaa
      781 aaactggagg agtcatacaa actgtttcta caatttgtaa gttaatacca cttattttaa
      841 taatggttgt tggatttatt aaaggtggtg gaaataatcc aatacttaca cctatggttg
      901 gtgaaggatt aagcctgggt agtgtactag gtcaagtttt aattgctata ttatttgctt
      961 ttgatggatg gatgaatgtt ggtactttag ctggagaaat gaagaatcct ggaaaagacc
     1021 ttccaaaagc tataataggt ggattgtcag ttgttatggc tgtttatttt ataataaatt
     1081 tagcgtatct ttgggtatta ccagctaatg aattagcaaa ttatgcttct cctgcatcag
     1141 cagttgctga agttatattt ggttcaatgg gtggaaaaat aatatctgta ggtatattaa
     1201 tttcagtgtt tggagcatta aatggatttt tactaactgg ttcaagggtg gcatatactt
     1261 tagctacaga taagacttta ccaaagtatg gtatattttc taaattaaat tctgctcaag
     1321 ttccagcaaa tgcaatagca ttagtatctg ttattgcatc tatatatgct ttgtcaggtc
     1381 aatttaattt attaactgac ttagctgtat ttgctacttg gatattctat gtattaactt
     1441 ttataggggt tatgaaactt agaaagactc atccaaatat accaagagag tataaagttc
     1501 cattatatcc tattgttcct ataatagcta tagcaagtgg tatatttgtt gtagttaatc
     1561 aattgtgttt tgcaggtatg aaaactacta tgatatctat aggaggtctt gtaataacag
     1621 ctataggctt accagtgtat gcttatatga ctagaggagt aaaaagataa accaagtagt
     1681 ttacaaatgc ttcataatta aaataaaaga gactgtctca aatagagata agtctctttt
     1741 ttattgttaa aatggtaaag atatgtttaa ttttacaaaa aaagagcgtt ccatgaacta
     1801 aaaagtttat tttaaggtat tcattttatt tttagttttt tgattataaa attaaacatc
     1861 taaaaaatta tttattttaa aatactttat tttaaagtgt tttttatcaa actaagtgg
//
LOCUS       DAEHWO010000175         1898 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEHWO010000175 DAEHWO010000000
VERSION     DAEHWO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.178"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            95..379
                     /locus_tag="KNP54_003935"
     CDS             95..379
                     /locus_tag="KNP54_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894762.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(536..709)
                     /locus_tag="KNP54_003936"
     CDS             complement(536..709)
                     /locus_tag="KNP54_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase"
                     /protein_id="HBF0894763.1"
                     /translation="MKRKLSTYFKGYILGLCIAFLLFTFILKKLIIENIIGIIIGTGI
                     AFLLIYLFNKKRK"
     gene            complement(1150..1365)
                     /locus_tag="KNP54_003937"
     CDS             complement(1150..1365)
                     /locus_tag="KNP54_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894764.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(1376..1843)
                     /locus_tag="KNP54_003938"
     CDS             complement(1376..1843)
                     /locus_tag="KNP54_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBF0894765.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
BASE COUNT          771 a          203 c          235 g          689 t
ORIGIN      
        1 tataaagtaa tttgaagaat atggaaaaac ttgattagta cattattaat tagggtataa
       61 aatggtgtaa atagaatgat aaggggtgga tgaaatgctt gtatataata aaagttttta
      121 tcctaatgac atatttccaa gattagattt ttcaaaaata aaaaaacagt taaaattgat
      181 agataatgac ctgtcagatt ttggaagcat atgtataata gaaaaagaac attatacaat
      241 aagtgtaaac agtataggtg aaataaatgt gtattatgat ttagagtacg aaaataaggt
      301 gtatagaata gtttatgaga ttgaaaagtt atttaaatct caagttggaa ggtttagcat
      361 atctacatac agaaattgat aattaaaaaa gtagaaatta aaaaacttaa tactaaagat
      421 atagataaat atatgaggta acagctagag agagttgtta ccctttttaa atactaagta
      481 tatattattc ttattaattt tttgtaaatt cactaaaaga cctttttata gaatattatt
      541 ttcttttttt attaaatagg taaatcagta aaaatgcaat tccagttcca attattattc
      601 caatgatatt ttctataatt aattttttta atataaaagt aaataataaa aatgctatac
      661 ataaacctaa aatatatcct ttaaaatagg ttgaaagttt tcttttcata taatcaccaa
      721 cttgtatcag atttagttta cttaattaga gtataacagt gttgtaactt caaagagtat
      781 ctaaaagatt acaaatgtta gataaaatca tcaataatgt aatttataac acgtagctat
      841 aaactatgca ataatataaa tggaggtata agtaaatgaa aaagttccat gttttgctaa
      901 cagtttaaat aaatattagg tagaaaagaa tgtatatagg aatctgtggt aaaattatca
      961 atttaaaagt attatttagt gtgatacagt tcttataggt aatggataac aaatagataa
     1021 aggaacagtt tctttcttag aacatatttt gttatgactt taaacaaagt taatattaat
     1081 gtcaataata tagtaaaaga ataaaaatca tatagtataa taaaaaagag tgtttctaaa
     1141 cactcttttt taatcatttt catcttctac atattcaagt atatcacctg gctgacagtc
     1201 taaagctttg caaatttcgt ttagagtggt aaatctaata gcttttgctt ttccagtttt
     1261 taaaattgat aaatttgcat ttgtaatatc tattttttct gccaaatctt taagtgatat
     1321 tttccttttt gccatcatta catctaggtt aactactatt gccataacat cacctctata
     1381 tcgttaaatc attatcttct tttattttta tagctttatc aaatgtttct gcaattacaa
     1441 agcacattag tgcaaatata aaagagataa tcataagtgg tgagataccg ccactatcag
     1501 ttccaaaaat tcttatatta ttagtattta aattataacc attgatacat tcaattatag
     1561 tgtttatcaa taaacaaaat cccattacct taaacctttt tacattttca agtacgaatg
     1621 gggaatactt agtactatta attataaata tcaagaataa gatgactata aagtagtcag
     1681 aaaaatatag tattcttgca attaaagcga ttactttgtc agaactaaaa tcatataaaa
     1741 acataggtat catacataag aatattatac cagcaactcc taaaagtgat aatagaaaat
     1801 atagaaatac tgataatata ttactaaaaa attttgtaat cataaaatat catctccttt
     1861 atataaagta tattattgat tataatatac aatttatt
//
LOCUS       DAEHWO010000176         1793 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEHWO010000176 DAEHWO010000000
VERSION     DAEHWO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1793
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.179"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            200..1540
                     /locus_tag="KNP54_003939"
     CDS             200..1540
                     /locus_tag="KNP54_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBF0894766.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKINKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT          721 a          127 c          285 g          660 t
ORIGIN      
        1 atatagttat tattaaaaaa agcaataaaa agtttaattc aatttagcaa atttagtgat
       61 ataattaaaa aagaaaagaa atatggactt atttggaata attttgacaa tctatttact
      121 acatgtgtag agtcgtatat aattaaatta tacataaaat ataaaaaaat aatttagtaa
      181 tacgttagga gaaagtatta tgataaagtc aagcttattt tggaatattt tcattgcgat
      241 atcctttatg atagaatggt ttctttgtaa gaaaatgcta gattatacaa gtgagaaaag
      301 gatttctaac aaaaaaataa acttttgtat ggtaggtatt attgtttttg ctgacataat
      361 atattttttt gatgtacctc caaatataag agtaattata tctatgataa ttactattgc
      421 attttataaa atctcatatg atgtggggtt tataaagtct gtattaatat ccttaattta
      481 ttggatgtta ctaatcgcca cagatgcttt gagtatatct ttaacagttt ggcttaattc
      541 tataaatgac atgagtagta tggggacggg agatatatac agaattgagt ctataatatt
      601 gggaaagata cttttgattg tgtctttgct tttatataga gccttaaaga taaaacttaa
      661 tatagaaata aataaaagga cattatttta tatagttatt cctatagtcg ctaatatagc
      721 atcttttttt gtaatttttg aatacatatt taatccaggg tctggtagct taatacataa
      781 tttccaattc gttatgattt ctgttgtatt gcttatatca agtatcactt tagttttaat
      841 tgctaaaaaa ttacagcaat ataatacttt agttgtagaa aacaatatga ttaaaaatac
      901 tttgaagtat gaaaatgagt attatgaaga tatagaaaag aaatatttaa aaactagatt
      961 actaagtcat gatatgaaaa atcacatatt gtgtataaat gctatgatta aaaaaggtat
     1021 tgatgttact tcttatttaa ataatttgca ggtagaaatt cagagtaatg acttgttatt
     1081 taatactggt aattttatat tagatgctat attaagtgaa aagaaagagg tttgtgataa
     1141 gaatgatata gaactaaaaa taggaataaa ttttagttgt tgtgaagctg ttgaattagt
     1201 ggatatatgt catatatttt caaatatttt agacaatgca attgaggcat gtaataaaat
     1261 tgatagtgga aatagagtta tttgtgttaa aggtgatgtt atgcaaaatt tttatttaat
     1321 aagagttgaa aatactaaga taaataagat tattactaaa aatggagata ttttgacaga
     1381 caaaaaaggt tctcttcatg gacttggaat aaaaagtgta aaaaactctg taaataagta
     1441 tggtggtaat gttgtaattg aatatgatga taaaaaattt gtagttaaaa ttgctattcc
     1501 acttagaaat gtgaagaaag cagttaatca tgtgatttaa atgtatataa atttgatgtg
     1561 tagaaattta atatataaga attaatgtat aaaagtgatg catagaagtt taatatataa
     1621 gaattaatgt ataaaagtga tgcatagaag tttaatatat aagaactaat gtataaaagt
     1681 gatgcataaa agtttaatat ataagaattt aatatgtata aaagtgatgc ataaaagttt
     1741 aatatatagg aatttaatat gtataaaagt gatgcataga aatttaatat ata
//
LOCUS       DAEHWO010000177         1769 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEHWO010000177 DAEHWO010000000
VERSION     DAEHWO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1769
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.180"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            147..1745
                     /locus_tag="KNP54_003940"
     CDS             147..1745
                     /locus_tag="KNP54_003940"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBF0894767.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
BASE COUNT          680 a          216 c          274 g          599 t
ORIGIN      
        1 taaatttgta gtatttatgt aagaaataaa ttttatataa tattttttca ctaaattttt
       61 ttctttttac aacaaatact cactaccttt tgatataata tttttatcaa ttattattat
      121 attcaagttt tgaaaggagt attaaaatga gtttattagt tttcggacat aaaaatccag
      181 atacagattc aatatgttct gcaatttcat tagcacattt aaagaacaaa ctaggaataa
      241 aagcaacagc ttatgcttta ggagatatca gaaaagaagc taaatatgcc ttggattact
      301 ttaaggtaga tgcacctgaa attttagata atgttagaat acaagttaga gatttaaatt
      361 atgataaagt agtaccttta acaccaactt catctatatt agaggcttat aaccttatgg
      421 atgaaaaaaa tgttaaaaca ctacctgtaa cttatgatga tggaactttt gctggtatca
      481 ttactatgaa agaaatagct aaaaatctac ttcatcaaca ctttacaact atacacacat
      541 cactatcaaa catttgtaaa aaccttaatg gtactattct tgtggactgt ggtgaagata
      601 taaaaggtag agtagtcact ttatcatttg gaatggagac tctaatagag actttaaaag
      661 aaggagacat agctattgtt ggagatagat atgatagtat tgaatatgct attgatacaa
      721 aagttaaact tttaatactt actaatcata cagagatttc aaaagatttg ctagctcttg
      781 ctaagataaa tggagtgtct gttgtttctg ttgaaagtga caattataaa acttctaatg
      841 taataaatca atgtagtttc ttagactcta tagaagctac agaaaattta attacattca
      901 aagaagatga ttatatggat gaaataaaag agattatgct agaaacaaac ttcagatctt
      961 atccaatatt agatgatgat aataagtttt taggtttagt ttcaaaaggt catctattaa
     1021 acccatctaa aaagaatgtt gttttagttg accataacga atatgctcaa agtgctgatg
     1081 gaattgaaca agcaaacata gttgaaataa ttgaccatca taaacttggt ggtatttcta
     1141 ctgatgttcc tatgtcattt agagttatgc ctgttggatg caatagtact ataatttatc
     1201 aaatgtacaa agaaaataat gttgagatac cttatgaaat agccgggctt cttttatctg
     1261 ctatattatc agatacatta ttatttaagt ctccaacaac aactgatata gataagaaag
     1321 cttgtgaaga attaagtaaa atagcaaaag tagacatgga aaaatacgct atggatatgt
     1381 ttaaatgcgg tacttcttta gatgaatata ctatagaaga aatagtaaat atggacttta
     1441 aagaatttaa tatgagtgga catagagttg gtattggaca agtatttacc ttagacatag
     1501 actctatatt tgctaaaaaa gatgagtttt tatcttatat aaattcgact gattatgaca
     1561 aactaattct tgcggttaca gatataatca aagaaggttc ttatttaatc tataaagcag
     1621 aagacagctt aattgctaac gcatttggtg ttgaaggtgt tcaaggtaca tttgcaccag
     1681 gtgttgtatc aagaaaaaaa caattagtcc ctaatttaac tactgcaatc aaaaatttta
     1741 aataatataa aatttttaaa taacgaaaa
//
LOCUS       DAEHWO010000178         1730 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEHWO010000178 DAEHWO010000000
VERSION     DAEHWO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1730
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.181"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            159..1649
                     /locus_tag="KNP54_003941"
     CDS             159..1649
                     /locus_tag="KNP54_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBF0894768.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
BASE COUNT          670 a          185 c          351 g          524 t
ORIGIN      
        1 tcagaaatat caataatatt atataataaa acaaaaaaac actatatata ttcgataaaa
       61 taaaatttaa acatataata ttttatgtat atattaataa aaggacatat tgtgttataa
      121 tggtatcgta taaaatcatt tacgggggtg gtattaaaat gtttcaattt gaaacacaaa
      181 tacacaaatt aagacatgat gttttaactg caatagctag acttggaaaa gaagataacc
      241 ttaccagaga agcaatggat aatattcagt atgaaataat aaaaggtgag aaacctacat
      301 acagatgttg tgtttataaa gaaagagcta taatatctga gagagtaaat gtaagtatgg
      361 ggttacaacc aggtcaagat aagatagatt tagatacaat ggatatagaa gaagatgaac
      421 aaattatata tattttggaa gctgcatgtg acagttgtcc aataaatgaa tttacagtaa
      481 cagatatttg tagaggatgt ctagcacata gatgtaaaga agcttgtaaa tttggagcta
      541 taacacatgt cggaggaatg gcctatataa atcatgaatt atgtaaggct tgtggaatgt
      601 gtaaaaaagc ttgtcaatat gatgccatct cagaggttgt tagaccatgt aagagtgttt
      661 gtccaactaa tgccttagga tttgatagag aaaatatgaa agctatgata catgaggata
      721 aatgtttaaa ctgtggagca tgtatgtcag catgtccatt tggagcaata tctgataaga
      781 gtttgatagc tcctgtagct agaaagttag ttcaaaaaga gaaaatgtat gcggtggtag
      841 ctccagctat aacaggtcaa gttgaagcaa atgttacata tggtcaaata aaaaatgcta
      901 taaaatcact aggatttgtt gatgtattag aagcagcttg tggagcagat gcagttacag
      961 ttcatgaaag cttagaattt gctgaaagaa tggaaaaggg agaagctttt atgacaaatt
     1021 cttgttgtcc aggatttgtt ggttatatag aaaaaacata cccaaatcat gtagggaaaa
     1081 tatcttctac agtatctcct atgatagcta gtggtagatt tataaaaagt catgaaccag
     1141 atgctaaagt tgtattcata ggaccatgta cagccaaaaa gagtgaggca gctaagaaag
     1201 aattaaaagg agctgttgat tatgtactta cttttgaaga aataatggca ttatttgagg
     1261 catttgatat agacttggct aagtgttcaa atgaagatat agatgatgca tcaatttttg
     1321 gaagaggttt tggagctgct ggtggtctta caaaagctat agaaaattat cttgctgaaa
     1381 aaggtattgg tgttaatttt gaacctgtaa agatttctgg ttcaagagaa atcaagaaaa
     1441 ctatgactat ggctaattta ggaaagctag aaggtaattt tatagaagga atgatgtgtg
     1501 aaggtggttg tataaatggt tctggtaaat tcttatcagg tgcaaaggtt aaagccactt
     1561 ttgatagaaa aaattctcaa tcaactaaga aaagtgtctt agcaaataca aagataaaag
     1621 attttagtaa tataaattta gaaaaataaa gataatacaa agcaacaaaa atacatattg
     1681 ttaatagagt tgttctaagt tgaggtttaa cttttggaca actctatttt
//
LOCUS       DAEHWO010000179         1709 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEHWO010000179 DAEHWO010000000
VERSION     DAEHWO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1709
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.182"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            178..1614
                     /locus_tag="KNP54_003942"
     CDS             178..1614
                     /locus_tag="KNP54_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBF0894769.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          697 a          169 c          282 g          561 t
ORIGIN      
        1 agttgatttt taatataaat gtaaatacaa ttatagctaa atgaataatt gtattaatat
       61 ttatttgtaa tatgcttaat ataatttgca attttacata agtttgttaa gtacataact
      121 aatttaagaa tatgtattta tatattaaaa atttattatg agggggacaa ttttattatg
      181 aaattctata aaagaatatt aacattgact ttaagtattt cttttgtatt tgcaaatatt
      241 caattagtag atgcaatatc atctgtagaa aaaatacaag gaaaaaataa gtatgaaatc
      301 gcaggtaaaa tagcagataa aaatgcatat aaaactgcta tattaattaa tactagtaac
      361 tctattgcag atggattaag tgcaagtgga ctagcaggag ctttaaatgc ccctatacta
      421 ttaactgaaa aaaatactat accaactgag acatctgcaa gattaaaaaa tgtatcaaaa
      481 gtttatataa ttggaggaac atattctatt agtacatctg tcgaaaattc attaaaatct
      541 aagaaaatga aagttgtaag aattaaggga aatgacagaa taaaaacaag ttataatgtt
      601 gcaaaagaaa taaattcaat aaaaaaagtc aatactgtta tgctaaccaa tgcatataaa
      661 ggagaagcag atgctataag tattgcatct gtagcagcaa gagataaagc accaataatt
      721 cttactaatg gacaaagtat acctttttca actagtggtt taaagtctta tgtaatagga
      781 ggaacagctt caatgagtac cactttagta aacaatacta aatctactag actagggggg
      841 agtactcgtt ttgaaactaa taaagcaata ataaataagt tttataagga tgctagagag
      901 ttttatatag ctggagctta tgaattaaca aatgcacttg taggatcttc tttatcaaaa
      961 catggtccaa tggttttagt taatgatggt agcaataaaa gcattttaaa aaatgctaag
     1021 aagataactt ctataggata tatagattca aatatagtac aacagtgttt aaatataaca
     1081 aatggaattg gagatattaa tactggggtt gtaaaaaatg ttaaacctac tacaaagact
     1141 ataaaagatg gaatgtataa ggttggaaaa gatatctcag caggtgaata cttaataact
     1201 tcaaactcag gaagttatgc ttcttattat gaagttacaa gtgatagtac aggtaatgct
     1261 gatagtatac tttcaaatga tatttttagt gggactagat atatcacctt aaagaatggt
     1321 caatatatta aaattgagga ttcaacaatg acattagcaa agtatgctaa agcccagaag
     1381 gccaagaatg gtaagtttgg aaatggtatg tataaaattg gattagaaat tcctgctgga
     1441 gaatatatta taatgtcaaa ttcttctgat gcatattatg aagttagaaa tgatagctta
     1501 ggtaatgcag agggaatagt tactaatgat actttttcag gaagaagata tataacggtt
     1561 gaggaaggtc aatatttaat attaaatgat tgttatttaa ttgaaaatga atagatgtaa
     1621 ttgtatttaa tagtaaatca tatattttat ttaaggaaag gtgttttaag ttttaattta
     1681 aaacatcttt ttattattat aataattat
//
LOCUS       DAEHWO010000180         1556 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEHWO010000180 DAEHWO010000000
VERSION     DAEHWO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.183"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(331..1038)
                     /locus_tag="KNP54_003943"
     CDS             complement(331..1038)
                     /locus_tag="KNP54_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBF0894770.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
BASE COUNT          493 a          276 c          132 g          655 t
ORIGIN      
        1 aatttttaat cttcatcaat accttttttg ctttcattgt taaaactatt ttttctatta
       61 gtttatttct tataaaacaa acatttagta ttaaaatata tatcacacaa tagtatttgc
      121 aatttaactt taaaaaaata aaaataccca actgacctaa gcaactcgat tgggtataaa
      181 taatctaaaa aatcattttt gtataaactc tttatttaac ttacattttt atttaccttc
      241 tactttaatt caacttatat ttctatgctt cttatactct cattcaactt atatttctac
      301 ttatcttata cttttataaa ttcatcacaa ttatttagtt ctcgctatca aagaaattgt
      361 attaaaatac tttccattct ctacttccat catttttttg tcatttatag catatgaatt
      421 atcacaattt atccaatcct tccaagcttc atcatgacaa tttaaagctt cacatttctc
      481 tacaatcaca gactccgatt cagaccaaag tttattccac catgtaattg aatggaagtt
      541 catattatct tgccaaaatg gaatgagttc atctggtata caatccacga aatcttcttt
      601 taatccaggc attgccatag caagtattcc cccctctttt acaagaggtg atatatgatt
      661 gtctaaaaat ccttctttgt ttccaaaata gtgataagaa tcgatactta tcaccgcatc
      721 aaagaaacct tctgcataag gtagttcatg tgcctctgcc tgtattggaa atattttatc
      781 atccaattta aactctttaa atcttttata gttttcagtt ggttctatcc ataaatctgt
      841 tgcaaataca gtagcatcaa attcctttgc taaaaatatc gaagatatac ccttaccaca
      901 acctaagtct aaaatacgca ttcccttttc tagttttatc ttacttgtta attcttccaa
      961 tatttttata caattaggtc ccatcatatt tttcatgaga aagtccttat cgtatttatt
     1021 actttttgta aatatcattc tatctttcct ttccctatca gttattattt attaaatttt
     1081 atacgtttga ttttttattt tttatctgct tcttatattg agcaatctct tttttattca
     1141 ttctttaaca gacaatttta atgtgtaatt ttatccactc tgtgatagta actttaatga
     1201 ataatcttat ctactgtgat agttatttta gtgagtaatt ttatctactc cacagcaatc
     1261 gctttaatga gtaatcttat ccactctatg atagttattt tagtgagtaa ttttatctac
     1321 tccacagtaa tcgctttaac gagtaatctt atctactcta taatagtcac tttaatgagt
     1381 aatcataatt tttatatcat tttagatact tactctaata agaattcatt ttctaatact
     1441 taataagttt taattacttc cactttaacc tatatactaa ttaacttatt taatttagtg
     1501 catatttgac actttacctt ttattatacc atttattatc ataaatataa taattc
//
LOCUS       DAEHWO010000181         1448 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEHWO010000181 DAEHWO010000000
VERSION     DAEHWO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1448
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.184"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            527..1177
                     /locus_tag="KNP54_003944"
     CDS             527..1177
                     /locus_tag="KNP54_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBF0894771.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
BASE COUNT          624 a          130 c          224 g          470 t
ORIGIN      
        1 atagtttaat ttgtagtaca ctagcatgat ttgcagaaca atgaattaat ctatagtata
       61 atagtttaat ttaaagtaca acgatttaat ctatagtaca ataacttgat ttgaagtaca
      121 acgatttaat ctatagtaca ataacttgat ttgcaataca atgaattaat ctatggtata
      181 atagtttaat ttgaagtaca atgaattaat ctatagtata atagtttaat ttgaagtaca
      241 acgatttaat ctatagtata atagtttaat ttgaagtaca atggtttaat ctatagtata
      301 atagtttaat ttgaagtata acgatttaat ctatagtaca ataacttgat ttgcaataca
      361 atgaattaat ctatagtata agagcatgat ttacagtaca ataatttaaa ttgtagtaca
      421 aaagtactat caaataagaa tttctacttt aaaaatatta ctaaaagtaa ttaaagtcca
      481 gtaattcaat ataatatggc aaaagaatag aaataaggtg agagtagtga aagtaaagtc
      541 aaatttagat gaaattttat atcataagat tattgaaagt cttattcgtg gtgaatactc
      601 tgtaggtcaa aaaatattac taaatgacct ttgtgaaaaa tttgaagtaa gcagaacacc
      661 agttgtacaa gcagtaaaaa tgctaaataa agatggagtg cttactatta tgacaaatgg
      721 taaagtgtac gtaccagagt atgaatatga tatggtaaaa caagtttgtg aaacgagaac
      781 actgattgaa acatatgctt tagaaaaaat gatgcaagaa gaggaagagg tttttcaaca
      841 aaagctagat gtaataaaaa gatactctga taaatgcgag gagtactatc gtcaagaaaa
      901 atctgtagaa cttgcactag cagatttgga attacataaa gccattgtag aaggggcaaa
      961 taatgagatt ttaaatgatg tatatgttgg tatacaagga agatttatag tagtgaacta
     1021 tttaattcga ccattaaaaa atcgtaatta tgaaggaaca gtacaagacc attttgaaat
     1081 attaaaattc attgaagaca gagatacaaa aaaagcagta gataaactaa gaaatcatat
     1141 tcaaggaact attaaaagat tctgtgaaga tgaataataa gttttgaagt tactatatat
     1201 acttatctat taagttgcta aatgtagtct aagtataatc taattatagt ttaaacataa
     1261 tctaaatata atctaataaa tataatctaa taaatataat ctaataaata taatctaaat
     1321 atagtgtaaa taagtctaag tatgaattaa atatagatta agtatggact aagtatagat
     1381 taagtataga ttaagtatag attaagtatg aattaagcat gaattaagca tggattaaat
     1441 atacttta
//
LOCUS       DAEHWO010000182         1337 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEHWO010000182 DAEHWO010000000
VERSION     DAEHWO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.185"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            27..101
                     /locus_tag="KNP54_003945"
     tRNA            27..101
                     /locus_tag="KNP54_003945"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KNP54_003946"
     tRNA            116..200
                     /locus_tag="KNP54_003946"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KNP54_003947"
     tRNA            210..293
                     /locus_tag="KNP54_003947"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="KNP54_003948"
     tRNA            323..399
                     /locus_tag="KNP54_003948"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="KNP54_003949"
     tRNA            407..482
                     /locus_tag="KNP54_003949"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="KNP54_003950"
     tRNA            571..659
                     /locus_tag="KNP54_003950"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="KNP54_003951"
     tRNA            663..738
                     /locus_tag="KNP54_003951"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="KNP54_003952"
     tRNA            745..818
                     /locus_tag="KNP54_003952"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="KNP54_003953"
     tRNA            833..909
                     /locus_tag="KNP54_003953"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="KNP54_003954"
     tRNA            933..1009
                     /locus_tag="KNP54_003954"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="KNP54_003955"
     tRNA            1017..1093
                     /locus_tag="KNP54_003955"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="KNP54_003956"
     tRNA            1102..1177
                     /locus_tag="KNP54_003956"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="KNP54_003957"
     tRNA            1185..1258
                     /locus_tag="KNP54_003957"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="KNP54_003958"
     tRNA            1265..1336
                     /locus_tag="KNP54_003958"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          352 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAEHWO010000183         1194 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEHWO010000183 DAEHWO010000000
VERSION     DAEHWO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.186"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..>1194
                     /locus_tag="KNP54_003959"
     rRNA            <1..>1194
                     /locus_tag="KNP54_003959"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          338 a          240 c          358 g          258 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tactaccgat aaccgtttga gagaagggat
      781 gacacagtag gataagctaa gcacactgtt ggttatgtgt gcccaagcat tgaggcagtc
      841 aaagtaggca aatccgcttt gataatgctg ggatgtgatg gggagcgaaa tttagtagcg
      901 aagtagctga tttcacactg tcaagaaaag tctctatcga ggttaaaggt acccgtaccg
      961 caaaccgaca caggtgggtg aggagagtat cctaaggcca gcgagagaac tgttgttaag
     1021 gaactcggca aaatgacccc gtaacttagg gataaggggt gccaccatta ggtggccgca
     1081 gagaataggc ccaagcgact gtttaccaaa aacataggtt tctgctaagt cgcaagacga
     1141 tgtataggag ctgacgcctg cccggtgctg gaaggttaag gggatctgtt agag
//
LOCUS       DAEHWO010000184         1135 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEHWO010000184 DAEHWO010000000
VERSION     DAEHWO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.187"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(217..1086)
                     /locus_tag="KNP54_003960"
     CDS             complement(217..1086)
                     /locus_tag="KNP54_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBF0894772.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT          429 a          175 c          107 g          424 t
ORIGIN      
        1 aataatctaa aatacatcaa aaaataaact aaaaaatatc gaaaaataat ttaaaagaca
       61 tcaaaactaa atcttctaat cagcaattaa aagtctattt tcttagttta aaaaataaag
      121 atagattttt tcaaaacact ggataaatag gtaaaaaaat aaacagttag taaaataaat
      181 ttttactaac tgtttatttt tattgtttaa tatgtcctat aaatcctcta agtaatattt
      241 tccttgcaaa aattctgatt ctaaacctag atttttaaaa taatcaacca tgcccataca
      301 cgcaaatttt tctgtagaat aatgagtagc acctataaca ttaattaaat tatcttttgc
      361 tatttgatgg aactctaata ctggttcaaa atgttttaaa ggcttagtaa acccagtaat
      421 atatagattt ataccaagtt cagcaacttc tcttgctaca aatggataac ttcctccccc
      481 tgctgcaata gcaactaaac catcttttaa tacagaatct ccataatcat acaatttcac
      541 atcatgacca acagattttt taattaattc cttaatctct tctattgatt ttagtgatgt
      601 tttacatata actcctacct caattttatc gtcatattta caaaatggtt tgactatttc
      661 taaacccata gcttttgcaa aactaacaga agttgaatag tcactatagt tgtctagtgg
      721 agaatgtaat acataaaaag aaattctacg atttttcatc tcttccatat aagatagtgg
      781 tatgtcgtga aatggaaaac cttcatctga tgctatgtat cccattgcat gatgtgaaaa
      841 aattaaaata tctttttcat ctttatctat aacttgctta attatttctt tatcaggaaa
      901 agtagttgtg tatactttat taatattttg agcattatct aatactaatc ctatgtattt
      961 ttttctaaat tctggagtaa taaaatcatt ttcaaaattc ataaaactcc aatcatcatt
     1021 aatattttta atattaaatt ctaaatctaa ttttttataa agttcaattg ccttaataat
     1081 aaccactcct ttataataat attgaattac tacatattaa tatagaaatt tccga
//
LOCUS       DAEHWO010000185         1079 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.188, whole genome shotgun sequence.
ACCESSION   DAEHWO010000185 DAEHWO010000000
VERSION     DAEHWO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1079
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.188"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            146..826
                     /locus_tag="KNP54_003961"
     CDS             146..826
                     /locus_tag="KNP54_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894773.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
BASE COUNT          485 a           63 c          164 g          367 t
ORIGIN      
        1 gataataaat atatataaat aataaagaaa atggatttat agtatttaaa atttcttata
       61 agggtaaaaa atgctattag aaaatgtact aaaaatattt ttccaattct ttatagaaaa
      121 ataatgatat ttaggagaga ttgtaatgca aattgatgta ttgataattg atggagataa
      181 gaatagttct caagagctga aaaatttttt agaaggaaag gggataaatg tctatttagc
      241 atataattgt aaagatgcta ttataaaaat atttagcaag aaatttgact taatattttt
      301 agagataatt ttagttgatg gtgatggttg ggatttttgt aaaaaaatta gaaatataac
      361 tacttgccca attattcata taacttatat aaatgaaaat caaagtattt taaatgcttt
      421 aaattctgga ggagatgatt atttaataaa gcctttaaat ttagaaatat tatatgcgaa
      481 agttaaagct attttaagaa gaagagattt atttttaaat aataataaaa ataatataaa
      541 actagaagat tataatagag ctagtggagt aataaagtta gaaaataaaa tgataaagtt
      601 aactccaaca gaaaatagat tattaaatta ctttatagag aatgctgaaa agactctaac
      661 tattaaggag atatatgaac atgtatggat gaatgagtat ttagatgata attatagtgt
      721 agtggttgct gtgagtggat taagaaagaa aatagagaaa gattataaaa atcctcaaaa
      781 aattataacg ataagagaag tagggtatta ctttaacaag atataaagct ttataaacag
      841 aatgaatgat aaggcataga taatatgtta gtatattata agagtttttg ttctaacgat
      901 atatttgtaa aattagattt aatttactta attaaattat agcagtagaa taaatataaa
      961 aaatgtctga aatattatag acatcagtaa aatatataaa actataatat aagtcgtaat
     1021 aataaaacaa atgaatatta attaataaaa agatagtagc tatttttata tagctatta
//
LOCUS       DAEHWO010000186         1074 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEHWO010000186 DAEHWO010000000
VERSION     DAEHWO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.189"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            109..1071
                     /locus_tag="KNP54_003962"
     CDS             109..1071
                     /locus_tag="KNP54_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBF0894774.1"
                     /translation="MQAISDKFDANRKTISELRKKGNTKAKYPYKTKKFYIIPFKASA
                     INRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNELNGVVAKGTN
                     TVGVDLGEIHSIASVTNKGVGLILSNREGRSIKQFRNKMYAYISKRLSKCKKGSRQSK
                     KLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVEKDTKKKKRL
                     NRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKKHKPTGRTYS
                     CTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
BASE COUNT          475 a          110 c          185 g          304 t
ORIGIN      
        1 tacatagtta acttatctaa agaatactat tttgaacata aacaatggat taaaaagaat
       61 gatatacaaa agttaatcaa aggtaagtac aatcttcata gtcaaactat tcaagctata
      121 tcagataaat ttgatgcaaa tagaaagact atatcagaat taagaaaaaa aggtaatact
      181 aaagcaaaat atccatacaa gactaagaaa ttttatataa taccttttaa agctagtgct
      241 attaatagaa atgctaaagg caacttaaaa ttatcaatgt caaaaggcag gtatttagaa
      301 ttagatttta atgttgagaa tataaaaact gctgaaatag tatggcgaaa tggatattat
      361 ttatactaca cttttgacaa tgaattaaat ggagttgtag ccaaaggcac taataccgta
      421 ggtgtagact taggggaaat acattcgata gctagtgtaa caaataaagg tgtagggctt
      481 attctatcta atagagaagg cagaagtatt aaacaattta gaaataagat gtatgcttat
      541 atatctaaaa gattaagtaa atgtaaaaaa ggtagtagac aatcaaagaa gttatggaga
      601 ttaaaaaata agataagaag taaaacagat aatcagttaa tgaatttata tcatcaaaca
      661 actagaaagt ttatagactt ttgtgtagag cagaaggtat gtgaaatagt tcttggggat
      721 ataaaagggg ttgaaaaaga tactaagaaa aagaaaagat taaacagagt taatagacag
      781 aaaatatctc aaatggagta tggtcgaata aaggactata taaaatataa agcaaaagag
      841 caaggtattg aagttaagtt agttaaagaa aactacactt ctcaaacttg cccaaagtgt
      901 tctaaaaaac acaaaccaac tggtagaact tatagttgta cttgtggtta tgaaactcat
      961 agagatatag ttggtgcttg gaatatttta aataaaaagc ataaatatgg tttagtagat
     1021 tttagaataa atcataagca accaataaat ttaaaagtat ctaccgtttg agcc
//
LOCUS       DAEHWO010000187          973 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEHWO010000187 DAEHWO010000000
VERSION     DAEHWO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.190"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..668
                     /gene="cdtR"
                     /locus_tag="KNP54_003963"
     CDS             <1..668
                     /gene="cdtR"
                     /locus_tag="KNP54_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBF0894775.1"
                     /translation="GFDNDVVRLYHNANLLLKELTEKNKVRIYFIVVDAKYKISNELC
                     DGLWIAQKIRESDYISPIIFLTNHIEMILGIFDYRLEVMDFILKHDMEIAESKIKACI
                     KIAHKRYIKEKNYRSNFFTIYSDFSLWKISFDEVIYFETSTIPHKIKLVTTSRIFEFY
                     KSLKSLPDLDACFIRVHKSFVVNKYHIVSLDLKKNNIKMSNGHICRISNTYRNILKNI
                     IKT"
BASE COUNT          401 a          106 c          118 g          348 t
ORIGIN      
        1 aaggttttga taatgatgtt gtaagattat atcataatgc aaatttgtta ttaaaagagc
       61 ttactgaaaa aaataaagta agaatatatt ttatagttgt agacgcaaaa tataagataa
      121 gtaatgaatt atgtgatgga ttatggatag cacaaaaaat tagagaatca gattatatta
      181 gtccaatcat atttcttaca aatcatatag aaatgatttt agggatcttc gattataggt
      241 tagaagttat ggactttata ctaaaacatg atatggaaat tgctgaaagt aaaataaaag
      301 cttgtattaa aattgctcac aaaagataca ttaaagaaaa aaattatcgc tctaattttt
      361 ttactatcta ttcagatttc tcactatgga aaatttcatt tgatgaagtt atatattttg
      421 aaacaagcac tattccacat aaaataaaat tagtgactac ttctagaata tttgaattct
      481 ataaaagttt aaagtcttta ccagatttag atgcatgctt tatccgtgta cataaatctt
      541 ttgtagttaa taaatatcat attgtttctc tcgacctaaa gaaaaataat attaaaatga
      601 gtaatggcca tatatgtcgt atatctaata catatagaaa tattttaaag aatattatta
      661 aaacataata aatagaaaaa ggagatgtct caagataaaa atttgaacca tctctttttt
      721 atacaaaaag agtaatccct aagaatcctc tatataataa tcatattgtg aaaaaacaca
      781 tactgactat atcatatata actactatta gatattataa caattgttcc tagattatga
      841 ttcgataaga tagctcatta aatcataaaa gtacgaaata gtctctttaa aatattcagt
      901 tgttattttg tactgacata tcatataaat acatattttt atgatatata cctacatatt
      961 ttatgaaatt tat
//
LOCUS       DAEHWO010000188          930 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEHWO010000188 DAEHWO010000000
VERSION     DAEHWO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.191"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     regulatory      <1..91
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            174..659
                     /locus_tag="KNP54_003964"
     CDS             174..659
                     /locus_tag="KNP54_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBF0894776.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          422 a           76 c          138 g          294 t
ORIGIN      
        1 agatataggc aatattagat aaatctaatg acgcaaaact atagggacta aaatctttat
       61 gtaataaagg tcatgtcagc cagttgccaa aaagataata attctttttg ttaaaagtat
      121 ttttagagtt atatatttta ataacttaat atttggcaag aggagggctt aagatgatat
      181 ctgaattaat gttaaaaaat tttcgcaaat ctagcatcaa ttttaagact aaaattaaat
      241 tgaatttaag agaaaaacca gacataaata gtttgaaatt aaaaagtata ccagaaggta
      301 aaattgttaa gttaaagtgt gtagatggaa tatgggcaga agttgagagt aattatgaca
      361 aaggttggtt actttataaa tatttagaaa gattaagtaa tgctaaaaac aatagtaatg
      421 atacaataaa aaatagaaaa aagaattaca taggaaatat aagaacaaat ggattaagtt
      481 tagaacttag aaatgataga acattagaat ctaaagttat aactacaatc cctgatggtt
      541 ttaaagttga agtatgttat agcgttggaa aatgggcaag agttaatatc aataaaaatg
      601 aaaaacgata ttctggatat gtatataatc aatacataga agagcattta agtttataat
      661 acgatactag caagctttaa atatattaat aaatcgcaaa aaagaatccc attaatggga
      721 ttcttttttg tagaaacatt ataacagaac taaagagaat aaattaacta atttattttt
      781 attataaagt aattataaat ggtaaattta attgaaagta gatttaactt atactttata
      841 caccaagtat cataaattaa tactactttg aaaaatctta aaaaaagtaa aagttatgat
      901 aataaaaata atattaaaga taataagata
//
LOCUS       DAEHWO010000189          847 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.192, whole genome shotgun sequence.
ACCESSION   DAEHWO010000189 DAEHWO010000000
VERSION     DAEHWO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.192"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..489
                     /locus_tag="KNP54_003965"
     CDS             <1..489
                     /locus_tag="KNP54_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBF0894777.1"
                     /translation="DTTKTELNTRIDTENEKQNIKIDQLIAGGSNVSHTHIIEIDDWI
                     LNNETNMYEVTINHPLLTKRILIALYDEIGEALTPNARAIDDNSILVRNEENIKMYVY
                     LINGNAETHFINATVDDNRVSEMTTYSSKKIEDRFLNLEEKVNGGLSSIATSVNELIT
                     YC"
     gene            506..>847
                     /locus_tag="KNP54_003966"
     CDS             506..>847
                     /locus_tag="KNP54_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894778.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWHTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQVMGTYYSMY
                     GGGATDIRLVGG"
BASE COUNT          316 a           98 c          169 g          264 t
ORIGIN      
        1 gatacaacta aaacagagtt aaatactaga attgacacag aaaatgagaa acaaaatatt
       61 aaaattgacc aattaatcgc aggtggttca aatgtatctc atacgcatat tatagagatt
      121 gatgattgga ttttaaataa tgaaactaat atgtatgaag taactataaa tcatccacta
      181 ttgactaaaa gaatactaat agctttatat gatgaaattg gtgaagcact tacaccaaac
      241 gctagggcta ttgatgataa tagtattctt gttagaaatg aagaaaatat taaaatgtat
      301 gtatatttga taaatggaaa tgcagaaact cattttataa atgcaactgt ggatgataac
      361 agagtgtctg aaatgactac ttattcatct aagaaaatcg aagatagatt tcttaattta
      421 gaagaaaaag taaatggtgg tttatctagt attgcaacaa gtgtaaatga gttgataact
      481 tattgttaga gaggagagtg agaaaatgca gacagaatgg aactttgggt acaatggttc
      541 gccacaaagt gttatattga aacctggcaa atataaattt gaatgctggg gttcttctgg
      601 aggtatcaac aattcttctt ggcatactga tgctaaaggc ggatattcta aaggtgaaat
      661 tacattaaaa aaacaaacta cattatatgt ttacgtcggc gaaagtggtt ttgcttcttc
      721 atctacgagt aataacacta aaagtggttt taatggcggt ggtaaaggtt atttaaatca
      781 acaggttatg ggtacttatt attctatgta cggtggtggt gctaccgata taagacttgt
      841 tggtggt
//
LOCUS       DAEHWO010000190          834 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.193, whole genome shotgun sequence.
ACCESSION   DAEHWO010000190 DAEHWO010000000
VERSION     DAEHWO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..834
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.193"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(178..645)
                     /locus_tag="KNP54_003967"
     CDS             complement(178..645)
                     /locus_tag="KNP54_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBF0894779.1"
                     /translation="MKFLNVLVVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          325 a          151 c           53 g          305 t
ORIGIN      
        1 tctaaattta aactttagta taaatatata agaaatatca taatattttt aaaaactcaa
       61 ataaagctaa acaagtatta tattctttat tttagaaaaa taaaaactgt aagcaaattt
      121 gttttcacac aagtttactt acagccttca cctcaatttt actttaatat aatccatcta
      181 ttctaaaact gattcaatat attcgacagt tacatccatt cttttagcta cctcatctat
      241 tgaaagacca ctatctaaaa aacgtctaca cacagatgac atagtttctc caacctcaat
      301 aatatgccca tctaaatcat aaaatctaat tgctctttga ccccacctat gctctatagc
      361 tagatgaaca taatctatat ctttcattgt actcaatctt tcaacaaaag tatcaaaatt
      421 atcttcctca aaatataact cagcatcatt tccattgaac ttaacttcac tgtcactctt
      481 attaataaat tctaaccaaa gctttttttc ttgtaatgat atattacctt ctaatacaac
      541 attttctcca aaatcacaga ttacctttaa ccccaaaaca tcataataaa acttttttga
      601 tttctcaata tcttcaacta ctactaaaac atttaaaaac ttcatattac ctccttaata
      661 tacacatact ttatttataa tatataatta gaattaaact ataaaggttt caataaggtc
      721 tagtataaag aaaaaaatta taagtcttat tgaaatagtt aagttaattt tatcatataa
      781 tataaatttt aatcttgtaa aaaacagaca tgttcatact tttaggttta aatc
//
LOCUS       DAEHWO010000191          787 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.194, whole genome shotgun sequence.
ACCESSION   DAEHWO010000191 DAEHWO010000000
VERSION     DAEHWO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.194"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(<1..>787)
                     /locus_tag="KNP54_003968"
     rRNA            complement(<1..>787)
                     /locus_tag="KNP54_003968"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          238 c          182 g          195 t
ORIGIN      
        1 cgtccatccc ggtcctctcg tactaaggac aggtcttctc aaatttccta cgcctgcgac
       61 ggatagggac cgaactgtct cacgacgttc tgaacccagc tcgcgtacca ctttaatggg
      121 cgaacagccc aacccttggg acctactaca gccccaggat gtgatgagcc gacatcgagg
      181 tgccaaacct ccccgtcgat gtggactctt gggggagata agcctgttat ccccagggta
      241 gcttttatcc gttgagcgat ggcccttcca cgcagaacca ccggatcact aagtccgatt
      301 ttcatccttg ctcgacctgt atgtcttgca atcaagctct cttttgcctt tacactctac
      361 gtacgatttc cgaccgtact gagagaacct ttgagcgcct ccgttacctt ttgggaggcg
      421 accgccccag tcaaactgcc cacctgacag tgtcccaaga ccagattcat ggcctatggt
      481 tagagtccca gtactacaag ggtggtatcc caaggatggc tccgccaaaa ctggcgtcct
      541 ggtttcaaag cctcccacct atcctgtaca tgtagtacca agacccaatg tcaagctaca
      601 gtaaagctcc atggggtctt tccgtcctgt cgcaggtatc cggcatcttc accggaatta
      661 caatttcacc gagtctgttg ttgagacagt gcccaaatcg ttacgccttt cgtgcgggtc
      721 ggaacttacc cgacaaggaa tttcgctacc ttaggaccgt tatagttacg gccgccgttt
      781 actgggg
//
LOCUS       DAEHWO010000192          754 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.195, whole genome shotgun sequence.
ACCESSION   DAEHWO010000192 DAEHWO010000000
VERSION     DAEHWO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..754
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.195"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..261
                     /locus_tag="KNP54_003969"
     CDS             <1..261
                     /locus_tag="KNP54_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894780.1"
                     /translation="HLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNYMNF
                     GITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            273..>754
                     /locus_tag="KNP54_003970"
     CDS             273..>754
                     /locus_tag="KNP54_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBF0894781.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     "
BASE COUNT          299 a           92 c          148 g          215 t
ORIGIN      
        1 catcttgaaa gtgatgctag aaatcaagat tggtttgagg aagttcattc ttttgtaagt
       61 aatattaagc catgtaatat gactttagat tacactagag tgcttataag caaagacaat
      121 tatatgaatt ttggtataac aaccctaatg ggtcaagaaa taactatata cccttggagt
      181 ccaccagata tagaaactta tggagaaatt gatgtattaa ctggcaatgg agttggatac
      241 caagagataa caatatttta ggaggtgata tattggctat agataaaagt tattacacta
      301 taattacaga tgtaggaaaa gcaaagatag caaatgcaag tgtcacaggt aataaagtgg
      361 gatttgtaaa aattcaactt ggtgatggag gagggagtga atatactcca actgagagtc
      421 agacagctct caaaaacgtg gtatgggaag gcaatattgg aaatacaact acagatgaaa
      481 ctgcaccaaa ttgtataata ttagagagtt taataccatc aagtgtaggc ggatttatga
      541 taagagaaat aggatattta gatgatgaaa ataatttaat tgccatttct aaatacaaag
      601 agtgttataa accttctata gaacaaggtg cagtggtaga catgaaggtt aaaactgtgc
      661 ttattgtatc taatgtaaat aatatagaac ttaaaattga cccaacaata atctttgcaa
      721 cactcaaaga tatacaagac ttagaaacta aaat
//
LOCUS       DAEHWO010000193          664 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.196, whole genome shotgun sequence.
ACCESSION   DAEHWO010000193 DAEHWO010000000
VERSION     DAEHWO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.196"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(<1..>664)
                     /locus_tag="KNP54_003971"
     rRNA            complement(<1..>664)
                     /locus_tag="KNP54_003971"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAEHWO010000194          636 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.197, whole genome shotgun sequence.
ACCESSION   DAEHWO010000194 DAEHWO010000000
VERSION     DAEHWO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.197"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            complement(<1..634)
                     /locus_tag="KNP54_003972"
     rRNA            complement(<1..634)
                     /locus_tag="KNP54_003972"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          140 a          175 c          117 g          204 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtcccg tggtactctg gatcatatct
      241 aaagtcttct cgtttaacat acaggactat taccttctgt ggtgggtctt tccaaacctc
      301 ttcaattacg atacctcttc gttatgatat gtccgcaacc ccaataaaga aaactttatt
      361 ggtttgggct aatccgcgtt cgctcgccgc tacttacgga atcgaatttc tttctcttcc
      421 ttcaggtact tagatgtttc agttccctga gttcccctca ttaagctatg tattcactta
      481 atgatactta gacattactc taagtgagtt tcctcattcg gaaatcttcg gatcaaagtt
      541 tacgtgcaac tccccgaagc ttatcgcagc ttatcacgtc cttcatcggc tcctagtgcc
      601 aaggcatccg ccctgcaccc ttaataactt gaccag
//
LOCUS       DAEHWO010000195          577 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.198, whole genome shotgun sequence.
ACCESSION   DAEHWO010000195 DAEHWO010000000
VERSION     DAEHWO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.198"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..>577
                     /locus_tag="KNP54_003973"
     rRNA            <1..>577
                     /locus_tag="KNP54_003973"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAEHWO010000196          562 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.199, whole genome shotgun sequence.
ACCESSION   DAEHWO010000196 DAEHWO010000000
VERSION     DAEHWO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.199"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..522
                     /locus_tag="KNP54_003974"
     CDS             <1..522
                     /locus_tag="KNP54_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBF0894782.1"
                     /translation="DTTKTELTNNLETAKTELNTRIDTENEKQNIKIDQLIAGGSNVA
                     STQTITIDDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENVVTNFKIIDDNTIEI
                     RSETRSELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKLSGGLS
                     NIATSVNELITYC"
BASE COUNT          245 a           60 c          106 g          151 t
ORIGIN      
        1 gatacaacta aaacagaatt aacaaataat ttagaaactg ctaaaacaga gttaaacact
       61 agaattgaca cagaaaatga gaaacaaaat attaaaattg accaattaat cgcaggtggt
      121 tctaatgtgg catctactca aacaataaca attgacgatt gggttgagga tgcagaaaat
      181 ggattcaaag caactgtaac acatagtttg ttaacacaga gaatagttgt aaatattata
      241 gatgctacta caaaagaaaa tgtagttaca aactttaaaa ttatagatga taatactata
      301 gaaattagaa gtgaaacaag gtcagaatta aacgtttatg tgataaatgg aaatgcagaa
      361 actcatttta taaatgcaac tgtagatgat aacagagtgt ctgaaatgac tacttattcg
      421 tctaagaaaa tagaggatag attggttaat atagaagaaa aattaagtgg tgggttatct
      481 aacattgcaa caagtgtaaa tgaattgata acttattgtt aaaggagagt gagaaaatgc
      541 agacagaatg gaactttggg ta
//
LOCUS       DAEHWO010000197          551 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.200, whole genome shotgun sequence.
ACCESSION   DAEHWO010000197 DAEHWO010000000
VERSION     DAEHWO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.200"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
BASE COUNT          219 a           43 c           67 g          222 t
ORIGIN      
        1 tggtaaattt atataaaaaa gaatatgagt tgtaaaatat taaataatat tgtactaatt
       61 ggaataattt taactttatt atagattatt ttaataccat tagtactgat ggtgtatttt
      121 aaaattggta taagcattac aaatacgaat atgccaactg taatatgtaa tataagtagc
      181 tatatacata tgtgctgtcc catatattgt atcattgttt atattaaaaa gattatgtaa
      241 attggtatca atcaataaat cattttcaga agaaatacct aaaaacttaa aaaataccta
      301 tatgtgtatt tagttagatt tgagattttt acatttaatt ttatagtgac aatattatat
      361 tatttttatg atgtctattt atatgcaatt actataatat cagaacttat agtatcattt
      421 gtttcattat caataaggtt ttttacttta gttttgtcaa ttttattaaa aaaagttatt
      481 gatataaaag ataagaagga taaaactata tgacggattt caaacataag agtggatatt
      541 tatataatag a
//
LOCUS       DAEHWO010000198          520 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.201, whole genome shotgun sequence.
ACCESSION   DAEHWO010000198 DAEHWO010000000
VERSION     DAEHWO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.201"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            188..304
                     /gene="rrf"
                     /locus_tag="KNP54_003975"
     rRNA            188..304
                     /gene="rrf"
                     /locus_tag="KNP54_003975"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            310..398
                     /locus_tag="KNP54_003976"
     tRNA            310..398
                     /locus_tag="KNP54_003976"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Leu,seq:taa)
     gene            410..486
                     /locus_tag="KNP54_003977"
     tRNA            410..486
                     /locus_tag="KNP54_003977"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:444..446,aa:Ile,seq:cat)
BASE COUNT          170 a           93 c          112 g          145 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgctaactc tatattttta aacttgtcaa
       61 aacttatgaa tttttaatag ttttataagg caaaaaatcg aataaaaaaa gtattgacac
      121 aataagacaa agatgttatt ataatacttg tcttagaaaa aaagttaaat gaaaatttag
      181 acaataatct ggttataata gcagagagga tacacctgtt cccattccga acacagaagt
      241 taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      301 aggtgatgtg ccgaagtggc ggaactggca gacgcacagg acttaaaatc ctgcgggact
      361 tacctctcgt accggttcga ttccggtctt cggcaccaca aattattgtg ggccattagc
      421 tcagttggtt agagcgcccg gctcataacc ggtaggtctg gggttcgagt ccctgatggc
      481 ccaccacaat aatttaaaga actttgaaaa ttaaacagta
//
LOCUS       DAEHWO010000199          496 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.202, whole genome shotgun sequence.
ACCESSION   DAEHWO010000199 DAEHWO010000000
VERSION     DAEHWO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.202"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            <1..>496
                     /gene="tuf"
                     /locus_tag="KNP54_003978"
     CDS             <1..>496
                     /gene="tuf"
                     /locus_tag="KNP54_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBF0894783.1"
                     /translation="GTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLD
                     QAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFD
                     GYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRT
                     VASGV"
BASE COUNT          213 a           61 c          125 g           97 t
ORIGIN      
        1 ggaacagttg caacaggaag agtggaaaga ggagtactaa aagtacaaga cgaagtagaa
       61 ttagtaggat taacagaagc accaagaaaa gtagtagtaa caggagtaga gatgttcaga
      121 aaattattag accaagcaca agcaggggat aatataggag cattattaag aggagtacaa
      181 agaaacgaga tagaaagagg acaagtacta gcaaagactg gatcagtaaa ggcacacaca
      241 aagtttacag cagaagtata tgtacttaaa aaagaagaag gtggaagaca tacaccattc
      301 tttgatggat atagaccaca attctatttc agaacaacag acgtaacagg agcttgtaag
      361 ttaccagaag gaatagagat ggtaatgcct ggagataacg taacaatgga agtagactta
      421 ataaactcaa tagttgtaga agagggatta agattctcaa taagagaagg tggaagaaca
      481 gtagcttcag gagttg
//
LOCUS       DAEHWO010000200          446 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.denovo.203, whole genome shotgun sequence.
ACCESSION   DAEHWO010000200 DAEHWO010000000
VERSION     DAEHWO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.denovo.203"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            2..400
                     /gene="tnpA"
                     /locus_tag="KNP54_003979"
     CDS             2..400
                     /gene="tnpA"
                     /locus_tag="KNP54_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBF0894784.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
BASE COUNT          179 a           52 c           80 g          135 t
ORIGIN      
        1 tatgtataaa tctaacaaaa atatagttta tgattgcaaa tatcatattg tattttgccc
       61 taagtatcgt aaacctgttt tagttggcga agttgaaaag atgttaaaag aaatactacc
      121 atataaagca gatgaacttg gagcagaaat aatagaaatg gaaactgata aagaacatgt
      181 gcacttatta atatcttgtg accctcaata tggaattcat aaagtagtaa aaggtttaaa
      241 aggctttagt tcgagagtat taagagagaa ctttccacat ttaaagtcta gtatgcctag
      301 catgtggact aatagctatt ttgtaggtac tgttggttct gtgagtttag aagtagttaa
      361 acaatatata gaaaatcaac aagttaggac aaagaaatga taaaaactca tagagtgaaa
      421 ttaaacctaa ctagaacaca atttga
//
LOCUS       DAEHWO010000201        15554 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.guided.098, whole genome shotgun sequence.
ACCESSION   DAEHWO010000201 DAEHWO010000000
VERSION     DAEHWO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15554
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.guided.098"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            246..863
                     /locus_tag="KNP54_003980"
     CDS             246..863
                     /locus_tag="KNP54_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBF0894785.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="KNP54_003981"
     CDS             971..3502
                     /locus_tag="KNP54_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBF0894786.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="KNP54_003982"
     CDS             3936..4637
                     /locus_tag="KNP54_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBF0894787.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5769
                     /locus_tag="KNP54_003983"
     CDS             4687..5769
                     /locus_tag="KNP54_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0894788.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            6030..7130
                     /gene="vanG"
                     /locus_tag="KNP54_003984"
     CDS             6030..7130
                     /gene="vanG"
                     /locus_tag="KNP54_003984"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBF0894789.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="KNP54_003985"
     CDS             7127..7933
                     /locus_tag="KNP54_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBF0894790.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="KNP54_003986"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="KNP54_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBF0894791.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..11023
                     /locus_tag="KNP54_003987"
     CDS             10403..11023
                     /locus_tag="KNP54_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBF0894792.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11189..11725)
                     /locus_tag="KNP54_003988"
     CDS             complement(11189..11725)
                     /locus_tag="KNP54_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBF0894793.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11838..12512)
                     /locus_tag="KNP54_003989"
     CDS             complement(11838..12512)
                     /locus_tag="KNP54_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBF0894794.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12715..14589
                     /gene="asnB"
                     /locus_tag="KNP54_003990"
     CDS             12715..14589
                     /gene="asnB"
                     /locus_tag="KNP54_003990"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBF0894795.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14681..>15554)
                     /locus_tag="KNP54_003991"
     CDS             complement(14681..>15554)
                     /locus_tag="KNP54_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBF0894796.1"
                     /translation="QELFFLYFLSQLGCDILYINPNKDILDLYPECSKFSTLFELSRK
                     TPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLTSKKIVQDEEVELSY
                     EDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVVNDGYSFLVRFENDD
                     KVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIVAIGSPLGLFNTVSD
                     GIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAGYDDGQNLNLAVESS
                     LVKIFANNFIEIVN"
BASE COUNT         5942 a         1695 c         2639 g         5278 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga ggcttgtttc cattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actaaggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatg acacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatagt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 gcttgaccct gatttaagag tatttgacat aattatgtat acaccttatg gaactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgtt gtaagtcata ctgaaccaga ccatgcagga agcgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataaaagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aagattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattatat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggc catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggtagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtc gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgatag aggtattgtt gtagataaga cattacagac
     3121 aaatgttaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtctcaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattgttt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatagt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattctttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgggt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt ataaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt atctttaagg ttattattcc gattgtagga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attataccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattc
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtgtttc ctgtactgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tataggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acgatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtagatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggat
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagagg aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtgccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgattagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc tacctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaga ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggt
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtataa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcatgta gtatatcgaa tgaattattg agcagagtag gaagaaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttactctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agttataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ctacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttgaa aatcataatt atgatttcca
    10981 tcataaaaaa catcacaatg ataaagatga taaaatgatt tagcttgtac gaaataaaac
    11041 gtatcttaaa atgatttagt actaaattat tttaagatac gttttatttt ttgtattaag
    11101 gtacaaaatt tttagttctt ttgtaaacta aaatatataa aacttattta tacttagttc
    11161 aaaatattgt tatttatttt ttctacaact ataataaaat ataaaattga tatccaatca
    11221 aaaaaataac tatgaaattt aatagcttag atatgaattt ttctgttttt gagttagttt
    11281 ttataggtag taaagaaatg tttatggtaa tgggataaaa caattcaata ccttctttag
    11341 taataaggtc aagacacaag tgagatagat atcctattat aaacccactg gacaaacatg
    11401 agaaaactat attattgtta gtgaagattg tcagagattt aaaaaaacta taaataagta
    11461 ataaggcaat tagactgtga gtaaaccctc tatgtctaaa cctacttcca aataatttgt
    11521 atattaacat aaatttttta cttatgtaag aacctctcat atctatatct ggaaataaag
    11581 aacctaaata tgcaaaataa atataaatta taattaatac tattttatat gcaatatcgt
    11641 atttaactag gtatagattg tttataaagg ggagtatcaa aagtgcgaat atataacctc
    11701 ccctttcatg tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta
    11761 tattggtaaa tttagactat cttttattat attatatagc aaacataagt ttttttcaaa
    11821 aggattttaa tatttaatta atcttgagat tttaaatttt tgtaattttc taaagcacca
    11881 ttccaattta ctacattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt
    11941 aaatagtaag catgctccca aacatcaagt cctattatag gagttaggtt tttacttaca
    12001 gggctatcct gatttggagt agtcataata gataatttgc catctttagt agctacaagc
    12061 caagcccaac cagaaccaaa gacatctaaa gcagattttt ggaactcttg cttaaatttt
    12121 tcaaaagaac caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt
    12181 tctggcgtca ttatatcaaa aaagaattta tgattataag ctccacctgc attatttctt
    12241 acagttgtag caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa
    12301 taattataaa gctcaggata tttttcaaga gcagcattta atttatcaac ataagcttga
    12361 taatgcttat catgatgcag tttcattgtt tctttatcta tataaggttc aagtgcatca
    12421 tatgcataag gtaatggttt aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa
    12481 gttatgcact gtgagattat aaataaagac ataataactg gtattaatat ttttttcttc
    12541 ataaaaatca cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag
    12601 ataatttata agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag
    12661 acaaaactat gaaatataga ataagactaa aggacagaaa ggaattttga ttatatggac
    12721 ggcaatattt caatttatta taaaggtgat atatctaaaa aagaagatat taaatttaaa
    12781 ataaaagaat ctgtaaataa tacaagactt tctagtagaa tagagtataa ggatgaggaa
    12841 aaaacttttg attttgaaag atttaatgta attgatgcta tttatggaaa taaaccattt
    12901 gaaaaagatg gaaaagttat tgtttttaat ggaaatatat ataactatca tgaaataaaa
    12961 gaagaattaa ttaaaaaagg acacaatttt actacaaatg atgatattga agtcttatta
    13021 gcatcttata tagaatttgg taagaattgt gtacataaga ttaaaggaat gttcaacttt
    13081 ataatctatg atagagaaaa tgaaagtata tttggagcaa gagatttatt tgggataaaa
    13141 ccactttatt atataaataa ggaaaatgca ataatttttt cctcagagta taagttttta
    13201 cttgaatata tgaaaaattt aaatataaat gaaagaagct tacaaagtta tttttcattt
    13261 caatatgtac ttcctgaaga tactatgata caaggaataa ggctgatacc agcaggtcac
    13321 tattttaggg tagaaaatgg tatactatct ttaaagagat ataataaact tgagtttaga
    13381 agtagtacaa aattttttta tactaaaaat cacttaggca atagagatgt gaatgaggat
    13441 gatataagaa atatagtagt agattcaata gtaactcata tggaagagga gaaagaaatt
    13501 ggaacatttt tgtctggtgg aatagattca tctattataa ctactgtggc ttcacaaatt
    13561 aatccaaata taaaatcttt ttctgcaggc tttagtgtca aaggatatag tgaattagaa
    13621 gtagcaaaga aaacagctga taagttaggt atagaaaata tccagattaa tataacacaa
    13681 gatgaatata taaaatcatt accgaatgta atttattctt tggatgaccc tatagcagac
    13741 ccttcagaag taggtcttta tttcttaatt aaagaggcag gtaaacatgt taaagtagca
    13801 ttgtctggag aaggagcaga tgaattattt ggaggatata atatatataa agagtatagt
    13861 actatgaaat cagttgtcaa ttcacctact tatattaaaa gtatattagg aagagtttca
    13921 gaacttatgc caaacataaa aggaagaaat tatctttata gagctacaac accattagaa
    13981 aaaagatata taggaaatgc aaaagttttt gaaaacagcg aagtaaaaag attctttttt
    14041 aagtataagg aaaagaatat atatgaatac ctgttgtcta atttgtatag agatgcacaa
    14101 aaaaataatt acgattatat aagtaaaatg caacatatag atgtgaatac atggcttcaa
    14161 ggcgatatac ttcaaaaaat tagcaaactt tctacagctg agcaggttga acttagagta
    14221 ccatttttat ataaagatgt atttgatgtc gcaaaaaatt taagaatgga gcaaaaaata
    14281 aataagaata atacaaaagt tttacttaga gaggcgttta gagaaatagt cccagaacat
    14341 gttgttcaaa ggaaaaaatt aggatttcca actccaataa gagtttggtt aaaagattct
    14401 ctaggggata ttgtaaagga aactatttat aattcaaatg tagatgaatt tatagataaa
    14461 aaatatgcaa taaaactttt agatacgcat cttaaaggtc atagagataa ttcgagaaaa
    14521 atatggacta tatttacatt ttgtctatgg catcaattat ttattgagca taaaaatgtc
    14581 gagtattaat acttttttca atattaatca gagggcaaaa gcatgcaatg ttttcaccct
    14641 cttgattatt atggaatagg ataagtagaa ttttgattga ttagtttact atctcaataa
    14701 aattattggc aaatattttg acaagactac tttcaacagc taaatttaag ttttgtccat
    14761 catcatatcc agcggaaatc aatcctagta agtttccaaa catatctaaa agagctcctc
    14821 ctgaactacc actagagatt ggagctgtaa attgtatcat ttgaaccgtt tcaaaatcac
    14881 gaaaagctga aataattcca tctgaaactg tattaaaaag acctagaggg cttccaattg
    14941 caactatttt ttgacctctc acaggttttt tactgacttt aacaggtatt ggcttgcatt
    15001 ttctatcaac ctttatcaca gctaaatcat aatctgaatg gtattttata atttggtaag
    15061 atgtataaac tttatcatca ttttcaaatc taactaaaaa tgaataccca tcattgacta
    15121 catgaagatt cgtaagtata taaccttcat tatttattac tactccagaa ccgctcttaa
    15181 acggtttatt ttcgttattg cacacaacaa tcataacaac agaagctgat aactttgcaa
    15241 ggtcttcata agaaagttct acttcctcat cttgtacaat ttttttagat gttagatttg
    15301 tgttattaag tgtattttta gagttaggtt tattcgtagt aggagaagtc ttattggtat
    15361 tttcactgta atttatattt gtaatatgcc tttcaaaagg tatttctaat atatttggag
    15421 tcttcctaga aagttcaaat agagtagaaa attttgaaca ttcaggatat aaatcaagaa
    15481 tatctttatt tggatttata tataaaatat cacacccaag ttgtgataaa aaatataaga
    15541 aaaaaagttc ttgc
//
LOCUS       DAEHWO010000202        15199 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.guided.099, whole genome shotgun sequence.
ACCESSION   DAEHWO010000202 DAEHWO010000000
VERSION     DAEHWO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.guided.099"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="KNP54_003992"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="KNP54_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBF0894797.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="KNP54_003993"
     CDS             1575..2258
                     /locus_tag="KNP54_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBF0894798.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="KNP54_003994"
     CDS             2255..4915
                     /locus_tag="KNP54_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBF0894799.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIKLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="KNP54_003995"
     CDS             complement(5096..6277)
                     /locus_tag="KNP54_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBF0894800.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="KNP54_003996"
     CDS             complement(6277..6939)
                     /locus_tag="KNP54_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBF0894801.1"
                     /translation="MAKILLLEDNDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            complement(7071..7709)
                     /locus_tag="KNP54_003997"
     CDS             complement(7071..7709)
                     /locus_tag="KNP54_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBF0894802.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="KNP54_003998"
     CDS             7888..8493
                     /locus_tag="KNP54_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBF0894803.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            8997..9746
                     /locus_tag="KNP54_003999"
     CDS             8997..9746
                     /locus_tag="KNP54_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0894804.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9743..10507
                     /locus_tag="KNP54_004000"
     CDS             9743..10507
                     /locus_tag="KNP54_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBF0894805.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVINDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10606..11427
                     /locus_tag="KNP54_004001"
     CDS             10606..11427
                     /locus_tag="KNP54_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBF0894806.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKNREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11441..13105
                     /locus_tag="KNP54_004002"
     CDS             11441..13105
                     /locus_tag="KNP54_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBF0894807.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            13110..14984
                     /locus_tag="KNP54_004003"
     CDS             13110..14984
                     /locus_tag="KNP54_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBF0894808.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLASIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT         5709 a         1744 c         2526 g         5220 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacttaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaataa taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtactacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataaa
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggagatag aatcctaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcaattagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctgtagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggt tgactgaaaa agatgcttca aaagaacttg cgaaaaatgg
     3901 aggatttaaa aatatagctt catctaaaaa gtactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 aatttctgta gacccaaagt tattttatga tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtgcagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaggtaa
     5701 ttggagtctt aagttgatga gcaatatctg caaggttatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatac aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ttgtcctcca ttctatatcc
     6301 tatgcctctt aatgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggattgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca ttatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttc atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcctta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatatttatg taaatataat atttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggaa aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagatgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatgatgaa atctataaga gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 gtagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 aattttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtagtagtaa
     8701 ttattaaata agataaaaaa taaatggcag atgaattaaa gtaatttcta ccatggaaaa
     8761 tacttttgag ttagaaaaaa ctctatttta gagtatgaag agatgaagct tccgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat accgtaattt ttcgtgtgaa aaaattgcaa
     9121 atgaatgtaa tgtttctaga gctactttat taaggctttg tagaaaaatt ggattagatt
     9181 cattctctga tttaaagtat ttacttaaaa ataatcaact agaatttgtt aataatgata
     9241 ataattttca tgatgtttgc gagaattatc gactattaat gaatgaatta caaaaaatat
     9301 catttcaaga tatttgtaaa ataatatatg atgcagaaac aatttatatt tatgggacag
     9361 gtaatgaaca gaaaagttta gctcaagaaa taaagagaat atttctttca gtaggtaaat
     9421 gtgttattga cttatttgat ataggtgaaa ttgaatttat gagagaatca tttcaaaaaa
     9481 gtgatttatt tattatcatt tctttgtctg gagaaacaaa agcaggaatt gaaattgcaa
     9541 aatttatcaa caatcatata catacgattt ctttaactag gcttgataat aatacaattg
     9601 caacactttg tgagtataat ctgtatgttg aaactcaaaa acttgataca ttacaagcta
     9661 tatcttatga agtcgtagga gcattttatg ctctattaga tttgcttcat atgaattaca
     9721 tagagtatag aaggagaaaa gaatgaaaat tgaaggactt ttcaataaat attataattc
     9781 atttacagca aatgataagt atatctgtga gtgtattctt aatcataaag aagattgtat
     9841 taaactttct atagatgaat ttgcagacaa ataccatata tctacaagtg cactttctcg
     9901 ttttgctcaa aaactacaat tacctggata tagtgaatta agagttatta tacgcttaaa
     9961 tgaaacagaa gtagaatata aaaatcaaag taaacaccaa ttaatggatt gctataataa
    10021 ggtgataaat gatatagaga agaaggattg ttcgattatg tttgaaagaa tgaaaaaggc
    10081 aaatcgtata atcgtctttg gagaaggtta ttctcaggaa agagttgcta aagagatgaa
    10141 aaggattttc ttaccaacag ggaaaattat atatgatgtt tatggttatg atatgattca
    10201 ggcacttaat cattttataa aaacagatga tatgattttc tttatttcat tgaatggaga
    10261 tgcatctaca attattgatt ttgctaaaga aatgagaatg aaaggaattt atatggtttc
    10321 tattacaaaa atgataagta atcctttagc aagattatgt gatgaaaacc tgtatattca
    10381 atctatatct atttctgtag ataaacaact ggactacgat gtaacaacac cttattttat
    10441 tttaattgaa ctgctttata ttaaatacaa gatgtattta gaaagtgaac atattccccg
    10501 aaaatgaaaa tttgtgctaa aaatgaacat attttttaaa agatatcaaa atattgatat
    10561 cttttttttt gaatgctatt atgattttga tagtaagaaa ggaagatgaa attgtacaaa
    10621 ttattaatac ttgatataga tggtacgctt agagatgagg tatatggaat cccagaatct
    10681 gcaaagcatg ctatacgttt atgtcaaaag aatcattgca gtgttgttat ttgtactgga
    10741 agaagtatgg gtacaataca agatgatgtt ttatcattag gagttgatgg atatattgca
    10801 ggaggaggta attacattca atatcatggt gaattacttt ataatcaatc ttttaatcaa
    10861 agattgataa aggaagttgt ttgtttatta aaaaatagag aagttgcttt ttcgattgag
    10921 agtcaggaaa aagttttcat gaatcaaaaa gccaaagaaa tatttgaaac aatgaatcag
    10981 ttgaaaggaa ctaattcttg tataaataaa caacatatcc aagaaaaaat aacatatgaa
    11041 aataacattg aagagtataa gtcacaagat atacataaaa tttgtttatg gtcaaatgaa
    11101 aaggtatttg acgaagtgaa agatatacta caagataaaa tggaattagc acagagagat
    11161 atttctagtc agtattatga aattattcaa aaagattttc ataagggcaa agcaattaag
    11221 agattacaag aaagattagg agtaactcaa aaagaaacca tatgttttgg tgatggtcaa
    11281 aatgacattg tcatgtttca agcatcagac gttacaattg caatgaaaaa tagtcatcaa
    11341 caacttaaag atatagcgac atctatatgt gaggacatat tcgataatgg aatttataaa
    11401 gaattaaaaa gaagaaatat catataaaaa ggagtaattt atggaaaaga aatggtggca
    11461 aaaagaaatc gtttatcaaa tttatccaag aagctttcaa gatagtaata atgatggaat
    11521 tggagattta cagggaatta tttctcgttt agattattta aaagatttag gtattacatc
    11581 attgtggtta tgtccaattt ttaaatcacc tatggatgat aatgggtatg atattagtga
    11641 ttatttggat attgcaagtg aatttggaag tatggaagat ttaaaagagt taattaaaaa
    11701 aagtaaagat agaggaatca aaattatatt agatttagtt cttaatcata caagtgatga
    11761 acatccttgg tttcaagaag cattaaaaaa tccagaaagt ccttatcatg attattatat
    11821 ttttaaaaaa ggaaacgatt tgccaaataa ctggaggtct gtttttggtg gaagtgtttg
    11881 ggaaaaggta gagaatagag acgaatatta ttttcattct tttggaaaaa aacaacctga
    11941 ccttaattgg gaaaatccaa tattaagaag tgaactttac caaatgatta atacctggtc
    12001 tcaaatggga gtggcaggat ttagagttga tgctattaca ttcatcaaaa agaatttaag
    12061 ttttcaaagt ttagaaagtg atggtgttga tggtcttgtt aaatgtacaa aaacagttag
    12121 aaatcagcct ggaatagaaa aaatgcttta tgaattaaaa gaaaatacgt ttaaaaaata
    12181 tgattgtatg actgttgctg aagcagcagg tattagctat gaccagttag gtgattttat
    12241 tggagaagat ggtttctttt caatggtctt tgactttaaa catgctgact tagatgttgc
    12301 ttctggtagt gagtggttta aaagaatttc atggacaatt ccagatttaa gaaaatgcat
    12361 tttagatagt caaatgtatg ttcaggaaca tggatgggca gctaatttta ttgaaaatca
    12421 tgaccaacca agagctacaa caaagtatct tttgcaatac gaaaggaatg atgatgcagt
    12481 aaaaatgttg ggagcaatgt atttcttttt aagaggaacc ccatttattt atcagggaca
    12541 ggaattagga atgacaaatt ttaaaagaga taccataaat gattttaatg atttatctag
    12601 cattgaccaa tactatcgtt caatagatga aggttactca gaagaagaag cgttagaatt
    12661 tgtgaattta agaagccgag ataatgcaag aacgccattt ccatgggcag ataaagaaaa
    12721 tgcaggtttt tcagatacaa caccatggtt aaaggttatt gaaaattata aagatattaa
    12781 tgcacagagt cagattaaca attcagagag tattttagaa ttttataaaa agatgataaa
    12841 gttgagacaa gatagtgagt attctgattg tttgatttat ggttcaatag aacctattga
    12901 tatagaaagt gatgatatta ttgcgtatag aaggcaatta gatttggtag ttattgattg
    12961 ttattataat ttttctgata aacctgtaga aataagagta gaagaaaaat atgatattgt
    13021 attccaaaat ttagatgata taaatctatt aaataaaaca gtgcgtttga aaccatttca
    13081 tgcagtatta ttgaaagtga ggtagaaaaa tgaataaata taataaaata gcaaatgagc
    13141 ttattaaaat tattggtgaa gataatatta tttctattac acattgtgcc acaagattaa
    13201 gagtgatggt taaagataga gaaattatta atgataagaa agttgaaaaa gttgatgagg
    13261 ttaaaggggt tttctttact tctggacagt atcaaattat tttaggaaca ggaatagtta
    13321 ataaagttta tgcagaagtt gaaaaaatgg gattaaaaac tttatcaaaa aaagaacaag
    13381 atgaattagt taaaaataat gaaactggat ttaagaaagt tatgagaact ctagcagata
    13441 tatttgttcc tattattcca gttattgcag caacaggatt attcttggga ttaaagggtt
    13501 gtttgtttaa tgataatgta cttggattat ttggaatgtc ttctgcaaat attccattgt
    13561 atattcagac acttgtttcg gttcttacag aaacagcatt tgctttttta ccagcaatta
    13621 ttgtatggtc agcatttaaa gtatttggag gaacacctgt tattggactt gttattggac
    13681 ttatgttagt ttccccaata cttcctaatg catattctgt tgctgaccca tcaaatgaaa
    13741 ttgaagcaat tatggcattt ggatttattc ctattgtagg ttgtcaagga agtgttttaa
    13801 cagctattgt tacagcattt attggagcta atcttgaaaa atggttccgt aaacatatgc
    13861 ctaatgtatt agaccttatt ttcacaccat tttttgttat gctaataaca atgttagtta
    13921 ttttgttagg tgtaggccct ataatgcata caatagaatt aaaaatggtt gatatcatca
    13981 gcttattgat tgatttgcct ttaggaattg gaggatttat tattggattt acatatccat
    14041 tagctgttat tactggctta catcatactt atgtaatgat tgaaacatca ctattagcaa
    14101 atacaggatt taatgccctt attactcttt gtgcaatgta tggatttgcg aatattggaa
    14161 catgtctagc atttatgaaa aaatctaaaa ataatcaagt taaacaaact gcagttggag
    14221 caatgctatc tcaacttttt ggtataagtg agcctgtttt atttgggatt cagcttcgat
    14281 ataatttaaa gcctttgatt attatgtgtg catcttcagg tttaggagca gcaatattat
    14341 caattttaca tattcaatct aattcatatg gattagcagt tttaccttct tatttaatgt
    14401 atatctatga tggatataat ttaatcacat acttattagc atcaatattt gtggttgcat
    14461 tctgctttat tgtaacatgt ttatttggag tgcctaaaga agctataaat gaagatgaag
    14521 acgaagaatt agtgtttaat gaaaataatg aaaactttgt gtctccagct aaggggaaaa
    14581 ttgttgcatt agaaaatgta ccagatgaaa cattttctaa aaaaatgtta ggtgatggtt
    14641 ttgctattga tattatagat ggaaaaattg tttctcctat ttcaggtaaa ttagaaacag
    14701 tggtttcaag tggacatgca tttgggatta aaggaactaa tggagaagta ttaattcatg
    14761 ttggaattga tacagttgca ttaaatggag atggctttga tattgctgtt aaacaaggag
    14821 atatggttaa acagggagat gttcttgtta atgttgattt aaagagaata catgaattag
    14881 gaaagtctac tttaacaatg gtattgtttc cagatggtaa gaaggtaaat attttggata
    14941 taaacaagga tgtaaaaata ggtcaaagaa tatgtgttga gtagtaggtg atatgtaatg
    15001 actacaaaag aagattatca agagtaattc aatcttttta aagtatgaga aataattcat
    15061 aaactctaaa acaattaaag aggttgtttc aaaatagaga ttgtattgca cccaaattgt
    15121 tgaaatgatg aaaatatatt taacttcata caaaaaatta aatagtggca acaattgagg
    15181 atgtgaggga gagttgcca
//
LOCUS       DAEHWO010000203        11059 bp    DNA     linear   BCT 02-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain Symptomatic Infection 2476
            SAMN04459219-rid12358333.guided.110, whole genome shotgun sequence.
ACCESSION   DAEHWO010000203 DAEHWO010000000
VERSION     DAEHWO010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04459219
            Sequence Read Archive: SRR3338981
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001055432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001055432.1
            Genome Coverage       :: 68x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/01/2021 06:30:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,018
            CDSs (total)                      :: 3,933
            Genes (coding)                    :: 3,884
            CDSs (with protein)               :: 3,884
            Genes (RNA)                       :: 85
            rRNAs                             :: 5, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 14 of 49
            Pseudo Genes (incomplete)         :: 24 of 49
            Pseudo Genes (internal stop)      :: 20 of 49
            Pseudo Genes (multiple problems)  :: 8 of 49
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11059
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04459219-rid12358333.guided.110"
                     /strain="Symptomatic Infection 2476"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collection_date="2012-05-21"
                     /collected_by="Leeds Teaching Hospitals NHS Trust"
     gene            323..661
                     /locus_tag="KNP54_004004"
     CDS             323..661
                     /locus_tag="KNP54_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894809.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            683..1000
                     /locus_tag="KNP54_004005"
     CDS             683..1000
                     /locus_tag="KNP54_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBF0894810.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1150..1827
                     /locus_tag="KNP54_004006"
     CDS             1150..1827
                     /locus_tag="KNP54_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894811.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2155..2922)
                     /locus_tag="KNP54_004007"
     CDS             complement(2155..2922)
                     /locus_tag="KNP54_004007"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBF0894812.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3594..4409)
                     /locus_tag="KNP54_004008"
                     /pseudo
     CDS             complement(3594..4409)
                     /locus_tag="KNP54_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            4510..5208
                     /locus_tag="KNP54_004009"
     CDS             4510..5208
                     /locus_tag="KNP54_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBF0894813.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            5296..5916
                     /locus_tag="KNP54_004010"
     CDS             5296..5916
                     /locus_tag="KNP54_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBF0894814.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            6072..6854
                     /locus_tag="KNP54_004011"
     CDS             6072..6854
                     /locus_tag="KNP54_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBF0894815.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            6979..7905
                     /locus_tag="KNP54_004012"
     CDS             6979..7905
                     /locus_tag="KNP54_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBF0894816.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            7919..8368
                     /locus_tag="KNP54_004013"
                     /pseudo
     CDS             7919..8368
                     /locus_tag="KNP54_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8728..9135
                     /locus_tag="KNP54_004014"
     CDS             8728..9135
                     /locus_tag="KNP54_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBF0894817.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            9137..9367
                     /locus_tag="KNP54_004015"
     CDS             9137..9367
                     /locus_tag="KNP54_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBF0894818.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            9757..9960
                     /locus_tag="KNP54_004016"
     CDS             9757..9960
                     /locus_tag="KNP54_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBF0894819.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            10038..10391
                     /locus_tag="KNP54_004017"
     CDS             10038..10391
                     /locus_tag="KNP54_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBF0894820.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10463..>11059
                     /locus_tag="KNP54_004018"
     CDS             10463..>11059
                     /locus_tag="KNP54_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBF0894821.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIK"
BASE COUNT         4078 a         1570 c         1741 g         3670 t
ORIGIN      
        1 caatatataa aatagaaaat ttttttaatt ttcaaaatat attctacata tctaatatgt
       61 aattacaata aaaaatgcta taattaacat attattaatt cgttttatta ttgtagtatg
      121 gctatgaaat tatgaaaata tttctctaat taaaaatatg atttatccat atttgtttat
      181 tgtagataca gactatacaa aaataaatag cacttatttc agtataaaaa catatatagt
      241 ctatatttag actaaaaaag tataaatagt ctatataaaa caacttaaac tatgaatata
      301 atctaaagtg gagggataat aattggcaaa tataggaaaa ataataggag atagaataaa
      361 agtctataga acaaaattgg gatatagtca agagtttcta gcagaaaagg caggtttaca
      421 tccaacatat attggtcaga ttgaaagagc tgagacaaat acatctatca atattataat
      481 gaaaattgct actgctttag acataccact tgaattgtta tttgcaaata ttattacaac
      541 agaaggcgtt gataactctg tacctttaga atgttatgaa atgattaata aattaactga
      601 aaaagaacaa attgcaatgc tagagttaat aaagtgcatc attaaataca aagaaatata
      661 agtgagggaa atagtaacaa taatgaatta tataggtaaa agacttaaag aagaacggaa
      721 aaaagcaaat ttaacttcaa aagaatttgc aaatatggtt ggagtatcgc cttggtatat
      781 aactcaaatc gaaagtggta aaaagaatcc aagtcttaaa acattcataa aatttgtaaa
      841 tatattaaat atttctgcag atgttcttat aaaagatatt acttccactg gaaaaacata
      901 tttagaaaat gatataaatg aagagttaaa agacttaaat tcaagagaac taaatctgat
      961 atcacagatt atagacatca taaaaaagaa taaaatataa ttctttatat tttatataaa
     1021 aaaaaaggtt atttgaaata aataaccttt ttttgtcttt ttgtgttaac attgtcttat
     1081 agtgctaatg agtactatta gaccatgttc tatggcctta ttttaatata aaacgattgg
     1141 agataggcta tgattgtgat tgaaggtagc gataaattta agattgcaaa agaatatatt
     1201 gatgtagaat atactctttt tagcaaagta acttttaggt atgaaaagtt gaaatttaaa
     1261 gataatgctg aattggaaaa aattaagatg tttaaatata aaaatggcta catccctaat
     1321 aaattaaacc tttcttttgg atatggattc tcttcttata aaaagcaaat aattagagaa
     1381 actgtagata ctttaagatt gacagaaatt ttttcaagcg agaacataga agatattaaa
     1441 tttataaaag atggtacaaa aaaattagaa attagcatag agaaagttgt gaaatttaaa
     1501 cgtcgaaaaa aaagaaatta tgtttgttgc tattgccctg atatgtatag agacataaaa
     1561 ctcgacaaag aatctatcaa taagatatac aacagaaaaa taaaaataga aagagaagtt
     1621 aatatttttg aagatgagga tgttataata aacaagaaag tattgaagtt tccaaagtct
     1681 tggacaaaga atatgcaaaa atattggtta agtgaaaata agtatcccat acattctact
     1741 gtaattgatg atgatagata taaatgttgt aatgtacaat atacaaaaaa tagagtgata
     1801 atattatatt acatatataa ccattaatat acataattac aaaaaaataa tgacaaatat
     1861 acataataca aatatatctt ctactttaga taaaacagtt attatgaaaa cttactatct
     1921 ataaataata gaaatgctag tataccatct ataatctaat gtctagtagg ttttaatggc
     1981 atattttaaa tatgccatag ttgatttata agattttcta tatcactttc aaaatacaca
     2041 ctaaatagtt gcttttcaga tataattgcc caatttaaat tttactatct gaaaagtttt
     2101 ttatatttaa tttatatctt caaaaatacc gtctaatatt tctatataat taatttaatt
     2161 aatactctta tgtaatagat taagtactga atttaactct ttaaatgata tttgccctgg
     2221 tgctgaaaca ctttttgcag ctccaaaagt caatgcagaa ccaaatattt caccacacaa
     2281 tctacttata acacccattc ctgacattga cattgttatt attggtctat ctgcataaat
     2341 tttaaacatt tcatttgtag cttcaagtag cactaacaca tctttttcat tttgcggcat
     2401 aacagctatt ttgggtaaat ctgcgcccaa ttcctgcatt ctacataaac gagatacaat
     2461 ctcttctttt tttggagttt tattaaaatc atgattagat ataattactt tcacttcttt
     2521 tttatgagca aaattaacta cttcatctat gacctcatct cccataaata actctacatc
     2581 tattaaatct actaaacctg tattagaaat ttctttattc aaagtagtat aataatctct
     2641 tgatattaat ttttctcccc cttctactac acttctaaat gtgaataata aagggatatc
     2701 atgtatataa cttcttaatt catagagaac ttccttaact tctttaatat tttctacatt
     2761 ctcaaaaaaa tcaactcgcc actctataat atccaaacat gcatctttta actctttagc
     2821 ctcttttata atatcttttt tatttttccc aataattggt acacaaattt taggtctacc
     2881 ttctccaata gtaatatttt ttacttgaac ttttcttttc atattctcct ccataatcag
     2941 aaattctata ggactttaaa ttctattttc tgcacaattt aattatacat taaaaatact
     3001 atacattata aaaatactaa tttaaaaata atttttattc taattcttaa aacaatccca
     3061 catattttag aaaaggtact ctataatata caaacacttc ttttttacct aaatttattt
     3121 taacatccta taattttcac aatattcttt aaattttact catataaaca atattattct
     3181 ggatgctaat agaattaatc tataaatcat agtataatta tgcagaaata actcgaattt
     3241 cactacttat gaagagattg aatattaatg aatctaaatc atttgcatta cttaagagtt
     3301 ttgactaaag ttgaacacca tacaaaagta gctactcaat tgtttatacc ccaaccaagc
     3361 ttaagtaatg ttatatagat tctcgaaaaa gaatttggta tctttttatt tgaaaaactt
     3421 atattaaatt tgattatctt ttcataagtt ggtaaatgtc gatatatcct gtatctacaa
     3481 ggagtatcgg cattttcttt ttggaagata ctttgcataa gttggcattt aaccgtataa
     3541 gaatgccatc aaaagtagta aataagtagt aaactctagt catactacta ggattataac
     3601 cgttccattt cagctctcga agaactaaat gaaccatgtg cataatagcc aagcgtcata
     3661 gtaatgtttt tatgccccat aatatattgc aatatattag gactcattcc tttgttagcc
     3721 atatttgtac agagtgtatg cctaaaggta tgtggcgtaa tctttggtag cttgtcctca
     3781 tgggtcttat tatacttctt gactaacgct cttaacatgc tttgataatg agttgcttgt
     3841 tttggtaatc catcttgttt aagaaatagg aagttctggt aaccatcaac aatgattggt
     3901 tctgctttag cgttcttacg ccgttccacg atacgttcaa atgattgata agctctttca
     3961 gtcattggaa tttctcgctt accctgtgtg gtctttggaa cttctacata atagccaatc
     4021 ttagtatcac tcaacaattg atggtctacc ataatggctt tatttttcat atccaattct
     4081 aaagtcaaac cgcataattc agaaatgcgt agtcctgttt ctaagaggat aacaacatca
     4141 tcataatatt tacaataagt cttatcgctc cccataaagg ataataagcc catttcctgt
     4201 tctggtgtta gagcgatttt tggttctgtt gtatcttcca aaacatcact taactaaaaa
     4261 ttaaatggat tctttctaat acagtcgtct tgaattgcca tgaaaaacga cgctttcagt
     4321 gagcgcttat aattgtcaat ggatttataa gcacacccat cttcactcat tcggatagcc
     4381 cagcttttag cgtctgataa tttaaccata tcaatgcttt ttgcacctag tgggtcattg
     4441 atagtatcta tattttgatt tataatttat acattttttt aaaaacagac ttttaactgt
     4501 aaagaatcta tgtataaact tagctatgtt gtccgtgtat ctacaaagaa tcttgacgag
     4561 ctaaaaaggc gttgtgatga agtcaaagac ttttacgacg acttatcaat caagctcgtg
     4621 cgtccctttg gggatatgtt gggattgcat ggcgaattta ttcctgtcag caaacgttac
     4681 atcaatgatt atattcaata tgtcacttcg gattttttgg ctggacttgg ttttggagcg
     4741 acacaaaccc ttggcgaaca tgaggatatc tatcttggct acaatctgga cactggaaag
     4801 aatgtctatc taaaacctgc ccttgctagt caaggggtaa agggttctat taccaatgcg
     4861 ttagcgtctg cgtttatcgg ttcattgggt ggtggtaaat tattcagtaa caatatgctt
     4921 gtttactatg cggtactatt cggcggacag gcggtcatag ttgaccctaa agcagaacgc
     4981 ggcaaatgga aagaaacgct accagaaata gcccatgaga taaacattgt caatttaacc
     5041 agtaatgatg aaaacaaagg attgcttgac ccttacgtca ttttgagccg taaaaaggat
     5101 tctgaaagtt tagcgattga tatcctaaca ttccttactg gtatctccag tcgtgacagt
     5161 gataagtttt tgcagaaaaa tgacaactgg aaaataataa tggaatagtt tctatgtaaa
     5221 tatattttta ctatcttacc taactaattg aaagatgata taatttaatc aaagatttgg
     5281 taaggaggga tgaatatgca tttaattgat tttatgaatg aagatattaa aaagaagctt
     5341 gttaaaaaaa cgtataaaaa gaaagagact attctttttg ctgagcaaga aaatgaatat
     5401 gtaattctta tgattgacgg tattgcagaa gcattcatct taaatgtgaa aggaaacatc
     5461 tcaacgattc atctttatag aagtggtagt ttttttggag aaatggaaca atttaatgat
     5521 gggaaaaaac ccgttgaaat tgtcgctttc acagattgta atgtatataa acttcataga
     5581 gatgattttt taaactggtt aaggggagat tttgaagcta caaaatttct gattcgagaa
     5641 atatctagta aattagttgt aaatgctgaa ttaattgaag aattatcatc tttaagtgtt
     5701 aaagaacgac ttctgaggtg tatatcctta cactattata gaagtgaatt aaatctgctt
     5761 accaaaaaac agcttgctag cgaagtaaac gctccaatta gaagcattaa tcgtgctata
     5821 aatgaatgtg tacaagaaca tctaattgct tatgaaaaca aaagatttag tgtaattaat
     5881 cagcgagagg tattaaagaa tcttcctaca acataagtat aatttcaaaa aagtattgaa
     5941 taataattat tcaatgcttt tttatttcgg gtcaagtgac ctattttttt ttatttcttc
     6001 attatataat actcctatgc ataattatgt tggattgata gctaataaaa gacagtgaga
     6061 ggtgttatat tatgactaaa acacaacaga aaatgataca aaacgtatta gaattttcaa
     6121 aaagagatag taggataata ggacttgcaa ttagcagttc ttatatcaca aaatcgttag
     6181 atgaatattc tgatttggat tttctgattg tagcagatga taaatcctat gaagaagtta
     6241 tcgaagagag attacttatt gtggaacagt ttggaacatt agtttctgct tttactggcg
     6301 aacacgttgg agaacctcga ttgataattt ccctctatga ttcccctgtt cttcatgttg
     6361 attttaagtt tacaacctta gatggtttac tagatagggt tgaagattca gctattctct
     6421 atgaagaaaa caactgcata acagaaattt attctaaaaa agaagcatac ttcccaactc
     6481 cagacttaca gtggattgaa gatagatttt ggatttgggt tcattacgct tgcactaaga
     6541 ttggacgtag agaactattt gaaacaattg attttttatc ttttttaaga caatcagtac
     6601 ttgccccatt aatacagctt ctcttaggta aattacctcg tggagttaga aaaattgaat
     6661 tggacgcacc ccaatatatt gaagcattag aaaagacggt tgctaaccat gaatataaaa
     6721 gctgtgttaa tgcattgcag gctactatca acctgtatct tgagttaaga gaggaattat
     6781 cacaaagtcc tattgtccga aaggttgaag ctgaaagggt tgcattacag tattttcaag
     6841 atttaatcaa ataaacccaa agtaaaaaaa tattgaatag taaatattca gtgttttttc
     6901 atttttggtc aaatgaccta gattagttgt tgtaacaatt ctataattat tttgaaagta
     6961 acagtatgga ggataactat gagtgatatt ttaagtagaa ttacaaataa aattggggat
     7021 aagaatatag ttgataagtt atcagctcta tcaaaatcag atttgaactc acttctatta
     7081 gaagtgtttg atagacaagc aaatacttta actgcaactg atattctaaa gtcataccaa
     7141 ctaaatagat ttactatccc tagcggtata gatccagaag aaattcatgc tttggaatca
     7201 aaattattga gaaaagcatt caatatggat atcaagacga ttatgctttc tccctctgcc
     7261 ccattaggta gctgtagcgt ttttggctcc gtagatcaat ataacgtagt aagtgctcta
     7321 cgagggacag aaacacttgc agacccctca aatatgttgg caataattat tgctgataaa
     7381 ttaaaaagaa aagaagaaaa taataccata cctatccaca tggctactac tgctagggta
     7441 ataagagcac aaaattttgt aggtaaaggt ttatattcac attttggctt atattgtatg
     7501 gtttcatctg gtatagatac agggtcttac acttgtgaaa aaatgttgtt agaaaagcac
     7561 ttaaactatt ataaagatat attaagtgaa atagaaaatg ttcgtttctc tattattcta
     7621 cgcaaaagaa acggatacaa agataatgac ggatttttcg acagaatggt tgaaactatc
     7681 aaacttattt ttcctaatat agagttatca attcataatg atgatgttga taataattat
     7741 tataaaggta tcaatttcaa attatcggtc aaacaaggaa atgaaaccgt tgaaatagtt
     7801 gacggtggat ttgttgactg gacttatcaa atgcttggaa ataaaagaga acgctgtttg
     7861 ataagtggta ttggcttaga aagatttctt gtagctgttt cataaaagga gaagaaaaat
     7921 ggaacttata gagtggaatt atgcttatat taccgattta gttgagtttg cgaatgataa
     7981 agaaattgca aagaatcttc gtgacaactt cccccaccct tatagggagc aaaacgctag
     8041 agattttgtt agtttttgtt tggcaacttc agatgttaaa caacttagct atgctatttt
     8101 ttatcaagaa agggctattg gaagtatcag cctaacattt gaagaagata cctctattaa
     8161 taaaaatgct gaattaggtt actggcttgc taggaactat tgaggcaaag ggatagcaac
     8221 aaatgcagta aaagaaatat gcaaaattgc ctttgaaaaa tacaacctta acaaaattca
     8281 tgctaatgta tattcctaca atagagagtc aagtaaagta ttggaaaaat gtggctttaa
     8341 gattgaagaa tactgtcaca attcataata aagaatagaa acatgattga ttgccatgta
     8401 tatagtttaa ttcgaccgca atagcattta ttagaattaa cctacttttt aataacagaa
     8461 taagtttttc ccctctatta atttcttatg catctttgta tttttatgaa aagctagcca
     8521 atgcatattt ccatacatca atatggtggt ggcttacaac caatataaat taaatacgtt
     8581 ttaaagaata cacatttttg ccctataggc agagtgtgta tttttttctc ttttttttga
     8641 aatttatcga agatttaacg ccctcccacc gtgataggag taagcaaggt tatttaactc
     8701 cttgcgatgg aaagagggtg aaatcttatg gttgatgaaa agacaattga acatcaattc
     8761 gacagtttct gtaaaacagt tttgcgtaac tatgctagag atatttatga cgaaaataaa
     8821 cgcagaaatg attatttggt atctctcgaa tctttgtcac ttgcagaatt aagtaaattg
     8881 agtattttag atgattatga ttctaactac atctgtatgg tttcttacga ctacaacata
     8941 cgaattgaag atgtattaat ggcgcaagca atcggaaaac ttacaaaaag aaaacaagat
     9001 ataattctac tttcattctt tttcaacatg acaaatgctg acatagcaac attgatggat
     9061 ttagcagaaa ataccataca ttatcacaaa acaaatgcac taaaagagtt gaaagaactc
     9121 atgcaggaac attgaaatga aacctactaa agaagtatta ccttttacaa ttattttact
     9181 tgctgtacat ggcgatgtaa atgcaataaa cgtaatactt aaacattttg aacactatat
     9241 cattcgtctt tcacagaaaa ctttatttga tgaatacgga aatccctata ttcatgtaga
     9301 agaagaaaca aagcgaatgc taggaacaaa actaatcact gctattttga gatttaattt
     9361 gtcttaatct cgccctctct ccatgtatca agctatttgg tacatggaga atcactaatt
     9421 atttgtctat aaaagcccac aagctattgt gattttttat aggcaaatca atgccgactg
     9481 ttctttgaca actgaataaa gtagatagat acgtttgtga tacagatagc caacaaatac
     9541 tatacgccat gaccttaatc aagagagcta ctatatagtg atttgtgaat aacctttgga
     9601 acggttgttt tgccgtaacc tgtaccacag tataatgata cacctgtatg acacggttct
     9661 gtccataaga atgggattgg ttgaaatacc aatggagctt atcaaagcca tctatctact
     9721 tctgaactac gaacatagaa aggagtgata cattatatga acaatactga tgtacctatt
     9781 tgggaaaaat ataccttgac gattgaagaa gcgtcaaaat actttcgtat tggagagaaa
     9841 aaattacgta aacgtgctga tgaaaacctt gattctggct gggtcattat gaatagcaat
     9901 cgcattcaaa taaagagaaa acaatttgag aaaatcgttg atacacttga cgttatctaa
     9961 tgaaattgag ccttatatgt tataatattc atatgacgta tcaagctcaa ttcggttatt
    10021 gagaggagct tcttatcatg tcaactgaaa aaagacgaga taataaagat agaattttaa
    10081 gaactggaga gagccagaga aaagatggaa gatacgcata taagtatgta tattcatttg
    10141 gtaaaccaca atttgtttac tcttggaaac ttgtacctac tgataaaccc ccaaagggaa
    10201 aacgtgatga tatatcatta agggataagg aaaaagcaat acaaaatgac cttgatgata
    10261 gcattgacac tattggtaag aaaatgacag tttgtcagtt atacgctaaa aagaatggac
    10321 taagaaagaa tatccgactt aacactaaaa aaggacgcca ttatcttatg aagattctta
    10381 acaaggagtg attctgtgaa gagatgtatt gtagtagtgg aatagtcaaa aacataatat
    10441 atattaaagg agagatttaa atatgactat tccaagttca aataaggtat atccaagaag
    10501 taatgattat caaactgtat atcttaaaaa tgtaataaca agggaaaata tagaagttgg
    10561 agattacaca atatataatg acttttataa tgacccaaga gattttgaga aaaacaatgt
    10621 attgtatcat taccctataa acaatgataa attaataatt ggtaagtttt gctcaatagc
    10681 atgtaatgca aaatttctaa tgactagtgg aaatcactca atgaaatcaa aatccacata
    10741 tacttttccc atcttttatg aagaatggaa actcgatatc aaccatataa cggacgcttg
    10801 ggacaataag ggtaacatta taattggaaa tgatgtgtgg ataggttatg attctataat
    10861 tatgtcaggt gtaaatattg gtgatggtgc aattattgga acaagagcag tagttactaa
    10921 tgacgttcca ccgtattcta ttgttggagg agtacctgca aaaattataa aaaagagatt
    10981 taataatgat acaatttcaa aattattaga aattaaatgg tgggattggc catataaaaa
    11041 aattcaatca aacattaag
//
